# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- HSP20 PF00011.16 EPY49146.1 - 2.8e-22 78.4 0.4 3.4e-22 78.2 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY49146.1 - 0.005 17.3 0.6 0.43 11.1 0.0 2.2 2 0 0 2 2 2 1 CS domain BON PF04972.12 EPY49146.1 - 0.046 13.4 0.3 0.32 10.7 0.1 2.1 2 0 0 2 2 2 0 BON domain PIH1 PF08190.7 EPY49146.1 - 0.092 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 adh_short PF00106.20 EPY49147.1 - 1.1e-11 44.8 0.2 1.2e-11 44.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY49147.1 - 7.6e-06 25.8 0.1 1e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY49147.1 - 9.1e-06 25.4 0.1 1.1e-05 25.2 0.1 1.0 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPY49147.1 - 0.0074 16.0 0.5 0.013 15.2 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPY49147.1 - 0.0075 15.3 0.5 0.012 14.6 0.3 1.4 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EPY49147.1 - 0.025 14.5 0.3 0.029 14.3 0.2 1.1 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EPY49147.1 - 0.049 13.0 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 EPY49147.1 - 0.055 13.0 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.13 EPY49147.1 - 0.058 13.0 0.1 0.062 12.9 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2620 PF10941.3 EPY49147.1 - 0.064 13.2 0.7 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2620 adh_short_C2 PF13561.1 EPY49148.1 - 8.3e-13 48.6 0.0 8.9e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Amidohydro_1 PF01979.15 EPY49150.1 - 4.9e-40 138.1 0.1 6.1e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPY49150.1 - 2.4e-18 67.1 0.0 4.9e-17 62.8 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPY49150.1 - 5e-14 52.3 0.1 9.9e-11 41.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPY49150.1 - 2.6e-10 39.9 0.0 9.1e-10 38.2 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase GST_C PF00043.20 EPY49153.1 - 4.5e-12 45.7 0.1 1.1e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPY49153.1 - 4.8e-09 36.0 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPY49153.1 - 5.3e-08 32.9 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPY49153.1 - 2.5e-07 30.4 0.3 6.8e-07 29.0 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPY49153.1 - 1.5e-06 28.3 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPY49153.1 - 0.0035 17.7 0.1 0.0075 16.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Oxidored_FMN PF00724.15 EPY49154.1 - 3.5e-151 503.0 0.0 3e-87 292.7 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EPY49154.1 - 0.016 14.7 0.0 8.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Tautomerase enzyme Pentaxin PF00354.12 EPY49154.1 - 0.088 12.2 0.0 18 4.6 0.0 2.5 2 0 0 2 2 2 0 Pentaxin family GST_C PF00043.20 EPY49156.1 - 8.5e-11 41.6 0.1 2e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPY49156.1 - 1.8e-10 40.6 0.0 3.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPY49156.1 - 1.8e-09 37.5 0.0 3.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPY49156.1 - 6.8e-07 29.4 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPY49156.1 - 0.001 18.8 0.0 0.0032 17.3 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY49156.1 - 0.04 14.4 0.1 0.15 12.5 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Oxidored_FMN PF00724.15 EPY49157.1 - 3.7e-146 486.4 0.0 2.8e-87 292.9 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EPY49157.1 - 0.015 14.8 0.0 8.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Tautomerase enzyme Pentaxin PF00354.12 EPY49157.1 - 0.079 12.3 0.0 16 4.8 0.0 2.5 2 0 0 2 2 2 0 Pentaxin family HSP20 PF00011.16 EPY49159.1 - 3.7e-23 81.3 0.5 4.4e-23 81.0 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EPY49159.1 - 0.033 13.7 0.3 0.05 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) BON PF04972.12 EPY49159.1 - 0.035 13.8 0.1 0.33 10.7 0.0 2.2 2 1 0 2 2 2 0 BON domain CS PF04969.11 EPY49159.1 - 0.042 14.3 0.6 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 CS domain Glyco_transf_8 PF01501.15 EPY49160.1 - 0.041 13.2 1.6 0.1 11.9 1.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 8 Helicase_C PF00271.26 EPY49161.1 - 1.2e-12 47.5 0.0 2.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY49161.1 - 5.2e-10 39.0 0.0 1.4e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPY49161.1 - 0.00034 20.5 0.0 0.024 14.4 0.0 3.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPY49164.1 - 1.1e-15 57.2 0.3 5.8e-15 54.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY49164.1 - 6.7e-09 35.4 0.2 3.2e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase BUD22 PF09073.5 EPY49164.1 - 0.00071 18.7 6.9 0.00071 18.7 4.8 5.6 6 0 0 6 6 6 2 BUD22 RNA_pol_Rpb1_1 PF04997.7 EPY49167.1 - 5.8e-125 417.0 0.0 9e-125 416.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EPY49167.1 - 6.1e-108 360.2 0.1 9.7e-108 359.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPY49167.1 - 1.9e-70 236.1 0.0 4.7e-70 234.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EPY49167.1 - 1.3e-66 223.8 0.9 2.7e-66 222.8 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 EPY49167.1 - 2.2e-50 169.8 3.2 4.1e-50 169.0 2.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 EPY49167.1 - 9.5e-50 168.3 0.0 1.9e-49 167.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPY49167.1 - 6.8e-39 131.9 0.1 1.6e-38 130.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EPY49167.1 - 2.1e-05 24.2 228.3 0.36 11.0 10.6 13.0 4 1 11 17 17 17 13 RNA polymerase Rpb1 C-terminal repeat HMG_box_2 PF09011.5 EPY49168.1 - 8.4e-17 61.3 2.5 2.5e-16 59.7 1.7 1.9 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EPY49168.1 - 4e-15 55.8 2.0 9.4e-15 54.6 1.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_5 PF14887.1 EPY49168.1 - 0.0063 16.2 0.4 0.0063 16.2 0.3 2.3 2 1 0 2 2 2 1 HMG (high mobility group) box 5 Ada3 PF10198.4 EPY49169.1 - 3e-32 111.1 10.2 5.5e-32 110.2 6.2 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 TFIIA PF03153.8 EPY49170.1 - 3.6e-65 221.3 0.4 4.3e-65 221.0 0.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Sel1 PF08238.7 EPY49171.1 - 6.9e-17 61.4 8.3 0.0072 16.9 0.1 9.1 9 1 1 10 10 10 4 Sel1 repeat TPR_8 PF13181.1 EPY49171.1 - 0.00026 20.5 4.4 0.002 17.7 0.2 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPY49171.1 - 0.014 15.0 0.1 0.014 15.0 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPY49171.1 - 0.89 9.2 18.8 0.051 13.2 0.7 4.0 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.1 EPY49171.1 - 3 8.4 12.0 15 6.2 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPY49171.1 - 3.3 7.8 8.3 1.6 8.7 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Mei5 PF10376.4 EPY49172.1 - 9e-32 110.3 0.0 1.6e-31 109.5 0.0 1.4 1 1 0 1 1 1 1 Double-strand recombination repair protein Cauli_AT PF03233.8 EPY49172.1 - 0.0021 17.7 0.2 0.0042 16.7 0.1 1.4 1 0 0 1 1 1 1 Aphid transmission protein Lzipper-MIP1 PF14389.1 EPY49172.1 - 1.3 9.2 6.3 0.68 10.0 0.6 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF2404 PF10296.4 EPY49173.1 - 2.4e-05 24.3 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) Aldo_ket_red PF00248.16 EPY49174.1 - 8.3e-43 146.2 0.0 1.1e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BCAS2 PF05700.6 EPY49175.1 - 7.9e-38 130.1 0.4 8.7e-38 129.9 0.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ATG16 PF08614.6 EPY49175.1 - 0.011 15.5 2.2 0.014 15.2 1.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Kinetocho_Slk19 PF12709.2 EPY49175.1 - 0.07 13.2 0.5 0.14 12.1 0.4 1.6 1 0 0 1 1 1 0 Central kinetochore-associated Pro_isomerase PF00160.16 EPY49176.1 - 5.2e-47 159.9 0.1 5.7e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1675 PF07897.6 EPY49177.1 - 5.5 6.7 15.3 1.9 8.2 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) ATP-sulfurylase PF01747.12 EPY49178.1 - 4e-86 287.7 0.1 5.8e-86 287.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EPY49178.1 - 1.7e-50 170.5 0.0 2.8e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Romo1 PF10247.4 EPY49179.1 - 1.7e-27 95.3 6.8 2.2e-27 95.0 4.7 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Uds1 PF15456.1 EPY49180.1 - 2.4e-25 88.9 3.0 2.4e-25 88.9 2.0 5.9 4 3 1 5 5 5 1 Up-regulated During Septation UPF0300 PF08594.5 EPY49181.1 - 0.00022 20.2 0.0 0.00052 18.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0300) YgbB PF02542.11 EPY49181.1 - 0.03 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 YgbB family DASH_Ask1 PF08655.5 EPY49182.1 - 4.3e-30 103.3 0.1 7.8e-30 102.5 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF2890 PF11081.3 EPY49182.1 - 0.21 11.6 5.1 0.14 12.1 1.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2890) PGA2 PF07543.7 EPY49183.1 - 2.7e-36 124.4 0.9 3.3e-36 124.1 0.6 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF3698 PF12479.3 EPY49183.1 - 0.59 10.2 3.2 0.85 9.7 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3698) DUF2183 PF09949.4 EPY49184.1 - 1.6e-26 92.1 0.0 4.9e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DNA_topoisoIV PF00521.15 EPY49185.1 - 1.8e-24 86.3 1.1 2.3e-24 86.0 0.8 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TFIIE_alpha PF02002.12 EPY49185.1 - 0.093 12.2 1.9 0.65 9.5 0.3 2.5 2 0 0 2 2 2 0 TFIIE alpha subunit DUF1057 PF06342.7 EPY49185.1 - 0.1 11.3 1.6 0.95 8.2 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Kri1 PF05178.7 EPY49185.1 - 1.3 9.2 4.5 0.9 9.8 1.2 2.1 2 0 0 2 2 2 0 KRI1-like family KOW PF00467.24 EPY49186.1 - 4.7e-07 29.2 1.4 5.5e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 KOW motif OPT PF03169.10 EPY49188.1 - 1.5e-197 657.8 50.5 1.8e-197 657.6 35.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Aft1_HRA PF11786.3 EPY49189.1 - 3.1e-21 75.4 9.6 3.1e-21 75.4 6.7 2.9 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EPY49189.1 - 2e-12 47.9 2.3 2e-12 47.9 1.6 3.7 3 0 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 EPY49189.1 - 9.9e-11 41.4 4.2 1.6e-10 40.7 2.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EPY49189.1 - 9.8e-08 32.4 6.3 9.8e-08 32.4 4.3 5.1 5 2 2 7 7 7 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EPY49189.1 - 2.7e-07 30.2 4.7 5.3e-07 29.3 3.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF3469 PF11952.3 EPY49189.1 - 0.0013 18.3 0.2 0.0021 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) bZIP_Maf PF03131.12 EPY49189.1 - 0.057 13.7 3.7 0.11 12.7 2.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor CENP-R PF06729.7 EPY49189.1 - 0.25 11.0 5.9 0.31 10.6 3.2 1.9 1 1 0 1 1 1 0 Kinetochore component, CENP-R C2 PF00168.25 EPY49190.1 - 1.3e-12 47.3 0.0 2.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF600 PF04634.7 EPY49190.1 - 0.092 12.7 0.2 0.092 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF600 MBF1 PF08523.5 EPY49191.1 - 3e-24 84.8 1.6 3e-24 84.8 1.1 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EPY49191.1 - 5.4e-11 42.1 0.1 9e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EPY49191.1 - 7e-07 29.3 0.3 1.4e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EPY49191.1 - 0.0045 16.9 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3808 PF10300.4 EPY49192.1 - 1.3e-120 403.1 0.0 2e-120 402.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EPY49192.1 - 4.3e-05 23.0 0.7 2.9 7.5 0.1 3.7 3 0 0 3 3 3 3 TPR repeat DUF2892 PF11127.3 EPY49192.1 - 0.00088 19.0 0.9 1 9.2 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2892) DUF4217 PF13959.1 EPY49192.1 - 0.89 9.1 5.1 1.3 8.5 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4217) UPF0300 PF08594.5 EPY49193.1 - 0.046 12.6 0.0 0.097 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) Rep_fac_C PF08542.6 EPY49194.1 - 2.3e-17 62.7 0.2 2.1e-16 59.6 0.0 2.5 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPY49194.1 - 7.8e-14 51.6 0.3 1.2e-13 51.0 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPY49194.1 - 4.2e-07 30.2 0.5 2e-06 28.0 0.2 2.2 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPY49194.1 - 2.5e-05 23.2 0.1 0.0028 16.4 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EPY49194.1 - 0.00084 19.3 0.4 0.0033 17.4 0.3 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPY49194.1 - 0.0017 18.5 1.9 0.016 15.3 0.2 2.7 1 1 2 3 3 3 1 AAA domain DNA_pol3_delta PF06144.8 EPY49194.1 - 0.0025 17.3 1.5 0.0044 16.5 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ABC_tran PF00005.22 EPY49194.1 - 0.0047 17.2 0.1 0.01 16.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Bac_DnaA PF00308.13 EPY49194.1 - 0.03 13.9 2.6 2 7.9 0.1 2.8 1 1 0 2 2 2 0 Bacterial dnaA protein AAA_10 PF12846.2 EPY49194.1 - 0.052 12.9 0.0 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EPY49194.1 - 0.097 12.4 0.1 0.87 9.3 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Mito_carr PF00153.22 EPY49195.1 - 1.4e-29 101.6 4.0 2.4e-16 59.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EPY49196.1 - 2.2e-33 113.8 4.5 3.2e-16 58.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.11 EPY49197.1 - 4.8e-35 120.4 7.8 4.8e-35 120.4 5.4 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPY49197.1 - 6.2e-10 38.4 20.0 3.5e-09 36.0 13.9 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPY49197.1 - 1.4e-09 38.0 33.1 1.5e-05 25.0 6.5 3.0 2 1 1 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EPY49197.1 - 0.0011 17.9 11.9 0.073 11.9 0.1 3.1 3 0 0 3 3 3 3 Eukaryotic protein of unknown function (DUF914) Multi_Drug_Res PF00893.14 EPY49197.1 - 0.031 14.7 1.9 0.031 14.7 1.3 3.7 4 1 1 5 5 5 0 Small Multidrug Resistance protein DUF2012 PF09430.5 EPY49198.1 - 9.3e-24 83.6 0.2 1.4e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EPY49198.1 - 0.00045 20.2 0.1 0.00094 19.1 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain EMP24_GP25L PF01105.19 EPY49198.1 - 0.011 15.4 0.1 0.015 15.0 0.0 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Cna_B PF05738.8 EPY49198.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Cna protein B-type domain GYF PF02213.11 EPY49199.1 - 2.5e-08 33.3 2.0 6.5e-08 32.0 1.4 1.7 1 0 0 1 1 1 1 GYF domain DUF1870 PF08965.5 EPY49199.1 - 0.1 12.2 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) TIP49 PF06068.8 EPY49200.1 - 2.8e-179 595.9 2.1 3.3e-179 595.7 1.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPY49200.1 - 1.5e-08 34.9 0.1 1.1e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPY49200.1 - 5.4e-07 28.8 0.9 0.00088 18.3 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EPY49200.1 - 4.7e-05 22.4 0.2 9.7e-05 21.3 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 EPY49200.1 - 5.9e-05 22.3 0.9 0.00085 18.5 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EPY49200.1 - 0.00026 21.0 0.0 0.0017 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY49200.1 - 0.00068 19.7 0.1 1 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EPY49200.1 - 0.0043 16.1 0.0 0.0094 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EPY49200.1 - 0.0056 16.1 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EPY49200.1 - 0.0057 16.3 0.1 0.97 9.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) CPT PF07931.7 EPY49200.1 - 0.013 15.1 0.5 0.085 12.4 0.3 2.2 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 EPY49200.1 - 0.021 13.7 0.4 0.52 9.1 0.0 2.3 1 1 1 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 EPY49200.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EPY49200.1 - 0.028 13.3 0.1 0.07 11.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Mgm101p PF06420.7 EPY49200.1 - 0.043 13.1 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 AAA_25 PF13481.1 EPY49200.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain JmjC PF02373.17 EPY49201.1 - 4e-28 97.9 0.1 1.1e-27 96.5 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 EPY49201.1 - 5.4e-08 32.2 0.0 1.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 jmjN domain Ribosomal_L36 PF00444.13 EPY49202.1 - 1.9e-19 69.3 7.3 2.4e-19 68.9 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 RNA12 PF10443.4 EPY49203.1 - 4.1e-130 434.1 0.0 8.4e-130 433.1 0.0 1.5 1 1 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 EPY49203.1 - 1e-06 28.2 0.0 2.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EPY49203.1 - 2.5e-06 27.3 0.0 9.1e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EPY49203.1 - 0.0023 17.9 0.1 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RRM_6 PF14259.1 EPY49203.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 EPY49203.1 - 0.058 13.3 0.0 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Apc15p PF05841.6 EPY49204.1 - 1.5e-10 41.8 6.0 4e-10 40.5 4.3 1.8 1 1 0 1 1 1 1 Apc15p protein DUF4200 PF13863.1 EPY49204.1 - 3.6 7.5 7.1 3.9 7.4 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Ribosomal_L37ae PF01780.14 EPY49205.1 - 6.4e-38 128.5 7.6 7.1e-38 128.3 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EPY49205.1 - 0.033 13.9 3.8 0.053 13.3 2.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EPY49205.1 - 0.035 13.5 1.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EPY49205.1 - 0.11 12.8 0.9 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EPY49205.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 EPY49205.1 - 0.26 10.8 0.2 0.26 10.8 0.2 2.0 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Lar_restr_allev PF14354.1 EPY49205.1 - 0.31 11.3 4.3 0.77 10.1 3.0 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-C2H2 PF00096.21 EPY49205.1 - 0.5 10.8 3.7 0.73 10.3 0.3 2.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type EF-hand_4 PF12763.2 EPY49206.1 - 4.1e-24 84.2 0.1 2.1e-09 37.0 0.0 3.7 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EPY49206.1 - 3.3e-07 30.3 0.0 0.00026 21.0 0.0 3.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EPY49206.1 - 8.7e-07 27.8 0.6 0.0048 16.0 0.2 3.2 3 0 0 3 3 3 2 EF hand UBA PF00627.26 EPY49206.1 - 1.8e-05 24.4 0.0 4.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain IncA PF04156.9 EPY49206.1 - 2.3e-05 24.1 13.8 5e-05 22.9 9.5 1.5 1 0 0 1 1 1 1 IncA protein EF-hand_6 PF13405.1 EPY49206.1 - 5.7e-05 22.6 0.7 0.68 9.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EPY49206.1 - 0.0008 18.9 1.3 0.078 12.6 0.1 3.0 1 1 1 2 2 2 1 EF-hand domain pair GAS PF13851.1 EPY49206.1 - 0.0012 18.0 9.6 0.0012 18.0 6.6 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EPY49206.1 - 0.005 14.6 10.1 0.008 13.9 7.0 1.2 1 0 0 1 1 1 1 Myosin tail DivIVA PF05103.8 EPY49206.1 - 0.01 15.8 5.2 0.035 14.1 3.6 1.9 1 0 0 1 1 1 0 DivIVA protein BRE1 PF08647.6 EPY49206.1 - 0.019 14.9 0.4 0.019 14.9 0.3 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 EPY49206.1 - 0.026 14.4 16.5 0.71 9.7 0.0 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EPY49206.1 - 0.1 12.3 11.7 0.34 10.6 8.1 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein LXG PF04740.7 EPY49206.1 - 0.26 11.0 9.7 0.16 11.7 4.5 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily V_ATPase_I PF01496.14 EPY49206.1 - 0.38 8.5 5.8 0.66 7.7 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EPY49206.1 - 0.46 9.4 8.8 0.98 8.3 6.1 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 4HB_MCP_1 PF12729.2 EPY49206.1 - 0.59 9.4 9.4 0.092 12.0 3.4 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction CENP-F_leu_zip PF10473.4 EPY49206.1 - 1.1 9.0 16.7 5.1 6.9 8.3 3.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EPY49206.1 - 1.9 7.5 12.6 0.055 12.6 3.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EPY49206.1 - 2.3 8.6 11.0 9.2 6.6 0.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) LMBR1 PF04791.11 EPY49206.1 - 8.7 4.8 5.8 31 2.9 2.4 2.3 2 0 0 2 2 2 0 LMBR1-like membrane protein NatB_MDM20 PF09797.4 EPY49207.1 - 1e-65 221.8 12.5 1e-65 221.8 8.6 1.8 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF3802 PF12290.3 EPY49207.1 - 0.097 12.9 0.2 0.097 12.9 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) SURF1 PF02104.10 EPY49208.1 - 5e-56 189.8 0.0 6e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Histone PF00125.19 EPY49209.1 - 4e-22 78.1 0.1 5e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY49209.1 - 0.0051 16.8 0.0 0.007 16.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 EPY49210.1 - 2.1e-74 249.9 0.0 2.4e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49210.1 - 1.9e-30 105.7 0.0 2.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49210.1 - 7.4e-06 25.1 0.0 0.00011 21.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EPY49210.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPY49210.1 - 0.0028 16.5 0.0 0.0059 15.4 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 WW PF00397.21 EPY49211.1 - 0.057 13.3 1.0 0.057 13.3 0.7 2.4 3 0 0 3 3 3 0 WW domain CDC50 PF03381.10 EPY49212.1 - 4.6e-91 304.8 0.5 5.7e-91 304.5 0.4 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.3 EPY49212.1 - 1.2 8.9 5.0 3.3 7.5 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DnaJ PF00226.26 EPY49214.1 - 4.2e-18 64.8 0.3 1e-17 63.6 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S15 PF00312.17 EPY49215.1 - 7.7e-20 70.4 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 PA28_alpha PF02251.13 EPY49215.1 - 0.014 15.5 1.9 0.023 14.8 0.3 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit EF-hand_like PF09279.6 EPY49215.1 - 0.34 10.9 2.4 2.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like Dor1 PF04124.7 EPY49216.1 - 1.2e-61 208.0 18.1 1.5e-61 207.8 12.6 1.0 1 0 0 1 1 1 1 Dor1-like family Peptidase_C11 PF03415.9 EPY49216.1 - 0.048 12.6 0.1 0.076 11.9 0.1 1.4 1 0 0 1 1 1 0 Clostripain family CENP-F_leu_zip PF10473.4 EPY49216.1 - 0.35 10.7 5.6 0.16 11.8 2.3 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Aminotran_1_2 PF00155.16 EPY49217.1 - 4.8e-64 216.5 0.0 5.8e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EPY49217.1 - 0.0031 16.2 0.0 0.0046 15.6 0.0 1.1 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.15 EPY49217.1 - 0.0065 14.8 0.0 0.026 12.7 0.0 1.9 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Glycos_transf_1 PF00534.15 EPY49218.1 - 1.8e-24 86.1 0.0 4.4e-24 84.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPY49218.1 - 1.5e-07 31.3 0.1 3e-06 27.0 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EPY49218.1 - 9.1e-05 22.6 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EPY49218.1 - 0.00017 21.7 0.0 0.0012 19.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EPY49218.1 - 0.0014 18.9 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EPY49219.1 - 3.7e-19 69.2 0.1 6.5e-17 61.8 0.0 3.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPY49219.1 - 4.3e-14 52.5 0.2 7.4e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPY49219.1 - 4.8e-08 32.6 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 tRNA_bind_2 PF13725.1 EPY49219.1 - 0.074 13.1 0.0 0.32 11.1 0.0 2.1 1 0 0 1 1 1 0 Possible tRNA binding domain Glyco_trans_4_4 PF13579.1 EPY49219.1 - 0.43 10.7 0.3 1.5 8.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Actin PF00022.14 EPY49220.1 - 6.6e-158 525.2 0.0 7.5e-158 525.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EPY49220.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fork_head PF00250.13 EPY49221.1 - 8.7e-34 115.4 0.1 2.2e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 Fork head domain Pkinase PF00069.20 EPY49222.1 - 6.9e-69 231.8 0.0 9.7e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49222.1 - 1.4e-33 116.0 0.0 2.1e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY49222.1 - 0.027 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPY49222.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY49222.1 - 0.076 11.9 0.1 0.34 9.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.27 EPY49223.1 - 0.0002 21.0 2.1 0.24 11.3 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat eIF2A PF08662.6 EPY49223.1 - 0.00026 20.7 0.1 0.013 15.2 0.0 3.1 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EPY49223.1 - 0.012 15.2 1.9 0.63 9.7 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_transf_15 PF01793.11 EPY49225.1 - 1.9e-121 405.0 11.1 2.4e-121 404.7 7.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 EPY49226.1 - 7.8e-46 152.3 20.0 2.3e-10 39.9 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPY49226.1 - 0.0011 18.7 0.1 0.3 10.7 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A TPR_11 PF13414.1 EPY49227.1 - 7.1e-08 31.9 1.1 7e-06 25.6 0.3 1.9 1 1 1 2 2 2 2 TPR repeat TPR_9 PF13371.1 EPY49227.1 - 0.00037 20.2 0.1 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPY49227.1 - 0.00043 19.9 0.4 0.048 13.5 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPY49227.1 - 0.002 17.6 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat FUSC PF04632.7 EPY49227.1 - 0.11 10.9 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2423 PF10338.4 EPY49228.1 - 8.6e-19 67.2 1.0 8.6e-19 67.2 0.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Laps PF10169.4 EPY49228.1 - 3 8.0 10.3 5.9 7.1 7.2 1.5 1 1 0 1 1 1 0 Learning-associated protein Fcf1 PF04900.7 EPY49229.1 - 5.3e-38 129.1 2.2 8.9e-38 128.4 1.5 1.4 1 0 0 1 1 1 1 Fcf1 Cdd1 PF11731.3 EPY49229.1 - 0.019 14.8 0.3 0.032 14.1 0.2 1.4 1 0 0 1 1 1 0 Pathogenicity locus Abhydrolase_5 PF12695.2 EPY49230.1 - 2.3e-23 82.5 0.0 3e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY49230.1 - 4.3e-16 59.5 0.0 4.8e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPY49230.1 - 7e-12 44.4 0.2 0.00077 18.0 0.1 3.1 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EPY49230.1 - 1.1e-08 35.0 0.1 3.4e-07 30.2 0.1 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EPY49230.1 - 1.8e-08 34.2 0.1 2e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPY49230.1 - 3.3e-07 29.7 0.0 1.1e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EPY49230.1 - 1.7e-05 24.2 0.0 0.0003 20.1 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.7 EPY49230.1 - 7.4e-05 21.6 0.0 9e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 EPY49230.1 - 0.0032 16.9 0.0 0.0068 15.8 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 EPY49230.1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EPY49230.1 - 0.014 15.0 0.1 0.025 14.1 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPY49230.1 - 0.019 14.3 0.6 1.1 8.7 0.1 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EPY49230.1 - 0.022 14.1 0.0 0.045 13.1 0.0 1.5 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EPY49230.1 - 0.031 13.6 0.0 0.056 12.8 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EPY49230.1 - 0.056 13.0 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EPY49230.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_C48 PF02902.14 EPY49231.1 - 6.4e-33 114.1 0.3 1.5e-32 113.0 0.2 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Vfa1 PF08432.5 EPY49232.1 - 1.9e-14 54.0 0.0 2.5e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CENP-N PF05238.8 EPY49233.1 - 5.2e-64 216.7 0.0 6.4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Ribosomal_S13 PF00416.17 EPY49233.1 - 0.11 12.9 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 S10_plectin PF03501.10 EPY49234.1 - 2.7e-42 142.5 0.0 3.2e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain WD40 PF00400.27 EPY49235.1 - 5.2e-53 175.1 11.4 6e-09 35.4 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPY49235.1 - 0.02 13.0 5.7 3.9 5.4 1.2 4.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 AAA_18 PF13238.1 EPY49236.1 - 2.9e-08 34.0 0.2 1.7e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPY49236.1 - 5.7e-07 30.3 0.1 1.3e-06 29.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EPY49236.1 - 2.8e-06 27.0 0.1 8.4e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EPY49236.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPY49236.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain YfiO PF13525.1 EPY49236.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.4 2 0 0 2 2 2 0 Outer membrane lipoprotein ABC_tran PF00005.22 EPY49236.1 - 0.097 12.9 0.0 0.41 10.9 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Amidohydro_5 PF13594.1 EPY49236.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase AAA PF00004.24 EPY49237.1 - 3.2e-46 156.8 0.0 1.1e-41 142.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPY49237.1 - 2.2e-06 27.6 0.0 7.6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPY49237.1 - 2.8e-05 24.1 0.2 0.0002 21.3 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY49237.1 - 4.3e-05 23.6 0.0 0.018 15.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EPY49237.1 - 0.00025 20.5 0.0 0.00085 18.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 EPY49237.1 - 0.0031 17.2 0.0 0.022 14.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPY49237.1 - 0.0033 18.2 0.5 0.018 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPY49237.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPY49237.1 - 0.01 15.2 0.0 0.029 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPY49237.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EPY49237.1 - 0.015 15.4 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TIP49 PF06068.8 EPY49237.1 - 0.021 13.5 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EPY49237.1 - 0.049 13.9 0.0 0.049 13.9 0.0 3.4 4 1 0 4 4 2 0 AAA domain Sigma54_activat PF00158.21 EPY49237.1 - 0.06 12.8 0.0 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain RuvB_N PF05496.7 EPY49237.1 - 0.076 12.0 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPY49237.1 - 0.086 12.8 1.5 0.18 11.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 EPY49237.1 - 0.12 11.4 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EPY49237.1 - 0.13 11.5 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TMEM223 PF14640.1 EPY49238.1 - 7.6e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Transmembrane protein 223 DUF2179 PF10035.4 EPY49238.1 - 0.043 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) RRM_1 PF00076.17 EPY49240.1 - 8.8e-62 204.6 0.6 3.9e-19 68.0 0.0 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49240.1 - 1.2e-52 175.7 0.4 1.3e-15 57.1 0.0 5.8 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49240.1 - 1.4e-33 114.4 0.0 3.5e-10 39.5 0.0 5.6 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Anoctamin PF04547.7 EPY49241.1 - 3.6e-84 283.0 23.3 4.5e-84 282.6 16.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DEAD PF00270.24 EPY49242.1 - 3.2e-38 130.8 0.0 9e-38 129.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY49242.1 - 1.4e-20 72.9 0.1 4e-20 71.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY49242.1 - 3.8e-05 23.6 0.0 8.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EPY49242.1 - 0.0065 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EPY49242.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Adaptin_N PF01602.15 EPY49243.1 - 3.9e-103 345.5 17.5 4.8e-103 345.2 12.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EPY49243.1 - 7.5e-32 109.6 0.0 2.6e-31 107.9 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EPY49243.1 - 4e-09 36.7 0.3 3.6e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Adaptin C-terminal domain RINT1_TIP1 PF04437.8 EPY49244.1 - 5e-82 276.0 19.1 6.6e-82 275.6 13.2 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family zf-DHHC PF01529.15 EPY49245.1 - 3.6e-27 94.8 6.8 3.6e-27 94.8 4.7 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Cytochrom_B_C PF00032.12 EPY49245.1 - 4.5 7.5 10.0 1.4 9.1 1.1 2.3 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD zf-RING_2 PF13639.1 EPY49246.1 - 1.6e-09 37.4 12.8 3.5e-09 36.3 8.9 1.6 1 0 0 1 1 1 1 Ring finger domain Pex2_Pex12 PF04757.9 EPY49246.1 - 2.5e-08 33.6 7.2 3.6e-08 33.1 5.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 EPY49246.1 - 3.6e-08 32.9 11.9 6.6e-08 32.0 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY49246.1 - 2.7e-07 30.1 7.7 4.9e-07 29.3 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY49246.1 - 3.9e-07 29.9 12.5 8.2e-07 28.9 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY49246.1 - 5.7e-07 29.1 9.3 1.1e-06 28.2 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPY49246.1 - 6.4e-07 29.1 9.9 1.4e-06 28.0 6.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPY49246.1 - 0.00027 20.9 11.2 0.00063 19.8 7.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPY49246.1 - 0.00046 19.8 4.2 0.0012 18.5 1.5 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EPY49246.1 - 0.017 14.9 4.0 0.038 13.8 2.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EPY49246.1 - 0.067 12.9 3.9 0.13 12.0 2.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 EPY49246.1 - 4.9 6.7 6.8 9.3 5.8 4.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit BPL_LplA_LipB PF03099.14 EPY49247.1 - 6.2e-21 74.6 0.2 9.8e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TatD_DNase PF01026.16 EPY49248.1 - 8.5e-54 182.4 0.0 1.1e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EPY49248.1 - 0.061 12.8 0.0 0.36 10.3 0.0 2.1 1 1 0 1 1 1 0 Amidohydrolase Pyr_redox_2 PF07992.9 EPY49249.1 - 6.5e-40 137.1 0.1 9.6e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EPY49249.1 - 6.5e-33 113.0 0.1 2.1e-32 111.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EPY49249.1 - 3.2e-21 75.5 1.0 3.8e-16 59.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPY49249.1 - 3.3e-11 43.6 0.3 4.3e-09 36.7 0.2 3.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPY49249.1 - 3.6e-09 36.2 0.2 4.8e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPY49249.1 - 5.6e-06 25.4 2.3 2.2e-05 23.4 1.5 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EPY49249.1 - 8.3e-06 24.9 0.7 8.3e-06 24.9 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPY49249.1 - 1.7e-05 24.7 2.8 1.7e-05 24.7 2.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPY49249.1 - 1.7e-05 23.8 1.9 0.00023 20.1 0.7 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EPY49249.1 - 2.2e-05 24.2 0.4 0.0031 17.1 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EPY49249.1 - 0.00033 19.7 0.0 0.00051 19.0 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EPY49249.1 - 0.00044 19.4 0.4 0.001 18.2 0.3 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EPY49249.1 - 0.0015 17.0 0.9 0.0015 17.0 0.6 2.6 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.1 EPY49249.1 - 0.0021 18.2 0.0 0.26 11.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EPY49249.1 - 0.0022 17.5 0.3 1.8 8.1 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EPY49249.1 - 0.0049 16.6 0.1 0.25 11.0 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EPY49249.1 - 0.027 13.5 0.2 0.54 9.2 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EPY49249.1 - 0.037 13.1 2.1 1.6 7.8 0.0 2.8 3 1 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EPY49249.1 - 0.094 11.6 0.3 0.25 10.2 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EPY49249.1 - 0.25 10.6 1.6 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 EPY49249.1 - 1 8.3 2.8 1.1 8.2 1.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DSPc PF00782.15 EPY49250.1 - 3.1e-34 117.4 0.1 4.8e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPY49250.1 - 4.9e-05 22.7 0.0 6.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TAP35_44 PF07265.6 EPY49250.1 - 0.045 13.5 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 CDKN3 PF05706.7 EPY49250.1 - 0.075 12.4 0.1 0.24 10.8 0.0 1.9 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) zinc_ribbon_5 PF13719.1 EPY49250.1 - 0.59 9.7 6.3 3.8 7.1 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPY49250.1 - 0.66 9.7 6.3 4.8 6.9 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EPY49250.1 - 3.4 7.5 9.9 3.2 7.6 3.3 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DnaJ PF00226.26 EPY49251.1 - 5.1e-24 83.7 3.4 5.1e-24 83.7 2.4 2.1 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.6 EPY49251.1 - 4.7e-19 68.6 1.0 4.7e-19 68.6 0.7 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 EPY49251.1 - 0.012 15.4 0.0 0.051 13.5 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1980 PF09323.5 EPY49251.1 - 0.31 10.7 4.2 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CBFB_NFYA PF02045.10 EPY49251.1 - 0.45 11.1 6.4 0.13 12.8 1.0 2.6 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B tRNA-synt_1g PF09334.6 EPY49252.1 - 4.1e-144 480.0 0.1 5.8e-144 479.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPY49252.1 - 2.9e-08 32.2 0.7 1.4e-05 23.3 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Y_phosphatase2 PF03162.8 EPY49253.1 - 8e-51 171.6 0.1 1.1e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EPY49253.1 - 1.2e-11 45.1 0.0 1.2e-10 41.8 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family UvrC_HhH_N PF08459.6 EPY49253.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal Y_phosphatase PF00102.22 EPY49253.1 - 0.0028 17.0 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EPY49253.1 - 0.032 13.8 0.1 0.095 12.2 0.0 1.8 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EPY49253.1 - 0.066 11.9 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.8 EPY49254.1 - 8e-51 171.6 0.1 1.1e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EPY49254.1 - 1.2e-11 45.1 0.0 1.2e-10 41.8 0.0 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family UvrC_HhH_N PF08459.6 EPY49254.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal Y_phosphatase PF00102.22 EPY49254.1 - 0.0028 17.0 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EPY49254.1 - 0.032 13.8 0.1 0.095 12.2 0.0 1.8 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EPY49254.1 - 0.066 11.9 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF2416 PF10315.4 EPY49255.1 - 2.4e-29 101.7 1.2 2.7e-29 101.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) DUF999 PF06198.6 EPY49256.1 - 2.5e-06 27.3 0.9 8e-06 25.6 0.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF999) DUF3675 PF12428.3 EPY49256.1 - 0.086 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) TcpE PF12648.2 EPY49256.1 - 2.6 8.2 9.7 1.3 9.1 4.6 2.1 1 1 1 2 2 2 0 TcpE family NIF PF03031.13 EPY49258.1 - 8e-44 149.1 0.0 1.2e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WD40 PF00400.27 EPY49259.1 - 3.2e-12 45.8 13.7 2.5e-05 23.9 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EPY49259.1 - 5e-06 26.3 0.7 5e-06 26.3 0.5 2.9 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EPY49259.1 - 0.0023 17.7 1.0 0.0074 16.0 0.0 2.4 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 TPR_19 PF14559.1 EPY49259.1 - 0.014 15.6 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EPY49260.1 - 1.9e-62 210.7 0.0 3e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49260.1 - 4.7e-36 124.1 0.0 8.1e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPY49260.1 - 0.022 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY49260.1 - 0.027 13.4 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EPY49260.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AdoHcyase PF05221.12 EPY49261.1 - 1.9e-142 472.9 0.0 2.2e-142 472.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EPY49261.1 - 5.2e-85 283.2 3.4 5.2e-85 283.2 2.3 1.5 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPY49261.1 - 6.1e-06 25.4 0.2 1.2e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EPY49261.1 - 1.5e-05 24.4 0.1 2.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EPY49261.1 - 0.0074 16.2 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EPY49261.1 - 0.0088 16.4 0.2 0.018 15.4 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 EPY49261.1 - 0.021 14.4 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4448 PF14610.1 EPY49261.1 - 0.035 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) 3HCDH_N PF02737.13 EPY49261.1 - 0.072 12.7 0.4 0.13 11.8 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_34 PF05637.7 EPY49262.1 - 1e-62 211.7 0.2 1.2e-62 211.5 0.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PE-PPE PF08237.6 EPY49262.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Methyltrn_RNA_3 PF02598.12 EPY49263.1 - 5.8e-58 196.5 0.0 6.6e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Radical_SAM PF04055.16 EPY49264.1 - 8.6e-14 52.0 0.0 2.1e-13 50.7 0.0 1.6 1 1 1 2 2 2 2 Radical SAM superfamily Syntaxin PF00804.20 EPY49265.1 - 4.7e-13 49.1 9.0 4.7e-13 49.1 6.2 2.9 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 EPY49265.1 - 1.3e-12 47.2 0.9 1.3e-12 47.2 0.6 3.1 3 0 0 3 3 3 1 SNARE domain Sed5p PF11416.3 EPY49265.1 - 5.4e-08 32.1 0.6 5.4e-08 32.1 0.4 2.7 3 0 0 3 3 3 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 EPY49265.1 - 0.00025 20.8 1.3 0.00025 20.8 0.9 3.2 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin-6_N PF09177.6 EPY49265.1 - 0.00035 20.9 11.8 0.003 17.9 2.2 3.2 2 1 2 4 4 4 2 Syntaxin 6, N-terminal KdpD PF02702.12 EPY49265.1 - 0.016 14.3 0.4 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DUF1664 PF07889.7 EPY49265.1 - 0.059 13.1 8.5 0.44 10.3 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.4 EPY49265.1 - 0.088 12.7 15.0 0.32 10.9 4.2 2.9 2 2 1 3 3 3 0 Golgi transport complex subunit 5 EB1_binding PF05937.6 EPY49265.1 - 0.57 10.5 8.2 12 6.1 0.0 3.1 1 1 1 3 3 3 0 EB-1 Binding Domain Baculo_PEP_C PF04513.7 EPY49265.1 - 2.3 8.0 15.9 3 7.6 6.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EPY49265.1 - 3.6 7.1 12.0 2.9 7.4 0.7 2.6 2 0 0 2 2 2 0 IncA protein DUF1515 PF07439.6 EPY49265.1 - 6.2 6.6 6.0 4.4 7.1 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) Cluap1 PF10234.4 EPY49265.1 - 10 5.2 17.4 0.83 8.8 6.1 2.2 1 1 0 2 2 2 0 Clusterin-associated protein-1 SHQ1 PF04925.10 EPY49266.1 - 2.4e-61 206.4 0.2 3.9e-61 205.7 0.2 1.3 1 0 0 1 1 1 1 SHQ1 protein Transcrip_reg PF01709.15 EPY49267.1 - 4e-67 225.7 1.9 4.5e-67 225.5 1.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator ATP12 PF07542.6 EPY49267.1 - 0.095 12.6 0.2 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 ATP12 chaperone protein Bromodomain PF00439.20 EPY49267.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain DUF4472 PF14739.1 EPY49268.1 - 0.078 13.4 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Ribosomal_L35p PF01632.14 EPY49269.1 - 0.00023 21.0 5.2 0.00029 20.6 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Methyltransf_31 PF13847.1 EPY49270.1 - 1.1e-14 54.3 1.5 3.4e-13 49.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EPY49270.1 - 4.1e-13 49.1 0.1 9.9e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EPY49270.1 - 1.4e-12 48.1 0.4 9.6e-12 45.4 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY49270.1 - 2.2e-10 40.5 0.0 4.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY49270.1 - 1.6e-09 38.1 0.7 1.5e-08 35.0 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EPY49270.1 - 2.9e-08 33.2 0.0 6.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EPY49270.1 - 2.6e-07 30.9 0.1 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY49270.1 - 2.7e-07 30.4 0.3 1.2e-06 28.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EPY49270.1 - 7.7e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.13 EPY49270.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.4 EPY49270.1 - 0.00033 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase zf-C2H2_2 PF12756.2 EPY49270.1 - 0.00046 20.2 2.4 0.0011 19.0 1.7 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Ubie_methyltran PF01209.13 EPY49270.1 - 0.00067 18.8 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EPY49270.1 - 0.0009 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EPY49270.1 - 0.0014 19.0 0.0 0.0048 17.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EPY49270.1 - 0.0043 16.0 0.1 0.0054 15.7 0.1 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 EPY49270.1 - 0.0058 15.3 0.0 0.0085 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 EPY49270.1 - 0.0079 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPY49270.1 - 0.01 14.9 0.1 0.054 12.6 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_15 PF09445.5 EPY49270.1 - 0.015 14.8 0.2 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.15 EPY49270.1 - 0.021 13.8 0.0 0.21 10.5 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase zf-Di19 PF05605.7 EPY49270.1 - 0.036 14.1 0.5 0.036 14.1 0.3 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PCMT PF01135.14 EPY49270.1 - 0.057 12.9 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EPY49270.1 - 0.096 12.0 0.2 0.19 11.1 0.0 1.5 2 0 0 2 2 1 0 Conserved hypothetical protein 95 RRM_5 PF13893.1 EPY49271.1 - 5.6e-12 45.3 0.8 7.3e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY49271.1 - 4.6e-08 32.5 0.2 1.1e-07 31.3 0.2 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49271.1 - 0.0001 22.2 0.2 0.00027 20.8 0.1 1.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPY49271.1 - 0.0048 16.6 0.1 0.0084 15.8 0.0 1.5 1 1 0 1 1 1 1 Limkain b1 TFIIIC_delta PF12657.2 EPY49272.1 - 7.9e-24 84.2 1.1 7.9e-24 84.2 0.8 3.0 3 2 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EPY49272.1 - 7.6e-19 67.4 6.2 7.6e-19 67.4 4.3 2.0 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex Npa1 PF11707.3 EPY49272.1 - 0.011 14.8 0.4 0.011 14.8 0.3 1.6 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal tRNA-synt_1 PF00133.17 EPY49273.1 - 8.4e-221 734.1 0.0 1.7e-220 733.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPY49273.1 - 6.2e-29 100.7 0.2 1.7e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPY49273.1 - 6.6e-18 64.5 1.5 2.7e-06 26.2 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EPY49273.1 - 0.013 14.6 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Sfi1 PF08457.5 EPY49274.1 - 2.7e-78 263.8 80.4 2.7e-78 263.8 55.8 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Histone PF00125.19 EPY49275.1 - 6.8e-32 109.4 0.1 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPY49275.1 - 6.3e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPY49275.1 - 0.0024 17.8 0.2 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPY49275.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EPY49276.1 - 7.2e-15 54.8 0.4 8.7e-15 54.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY49276.1 - 7.1e-06 25.9 0.1 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPY49276.1 - 5.8e-05 23.1 0.1 8.2e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EPY49276.1 - 8.5e-05 22.4 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 EPY49276.1 - 0.012 14.8 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EPY49276.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated DUF1819 PF08849.6 EPY49276.1 - 0.1 12.0 0.6 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) TFIID_20kDa PF03847.8 EPY49276.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UPF0220 PF05255.6 EPY49277.1 - 6.1e-57 191.4 6.4 6.8e-57 191.3 4.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.3 EPY49277.1 - 2 7.5 7.6 1.1 8.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Pkinase PF00069.20 EPY49278.1 - 2.2e-65 220.4 0.0 2.6e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49278.1 - 3.4e-27 95.1 0.0 4.6e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49278.1 - 6.3e-07 28.6 0.0 9.1e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPY49278.1 - 0.0019 18.0 0.0 0.014 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPY49278.1 - 0.09 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Porin_3 PF01459.17 EPY49279.1 - 2.8e-80 269.5 0.0 3.3e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin CorA PF01544.13 EPY49280.1 - 5.1e-46 157.0 0.0 7.9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ESSS PF10183.4 EPY49280.1 - 0.51 10.7 3.0 0.84 10.0 0.0 2.9 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CBP4 PF07960.6 EPY49281.1 - 2.4e-10 40.1 0.0 2.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 EPY49281.1 - 0.0057 16.3 0.0 0.006 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4574) G6B PF15096.1 EPY49281.1 - 0.1 12.0 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 G6B family Tom7 PF08038.7 EPY49283.1 - 6e-18 64.0 0.7 6.8e-18 63.8 0.5 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 EPY49284.1 - 2.3e-58 193.9 7.2 1e-18 66.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF1640 PF07798.6 EPY49286.1 - 6.9e-12 45.7 3.2 6.9e-12 45.7 2.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) LppC PF04348.8 EPY49286.1 - 0.0075 14.8 1.1 0.01 14.4 0.8 1.1 1 0 0 1 1 1 1 LppC putative lipoprotein DivIVA PF05103.8 EPY49286.1 - 0.023 14.7 3.1 1.1 9.2 0.6 2.4 2 0 0 2 2 2 0 DivIVA protein Phosphodiest PF01663.17 EPY49287.1 - 3.8e-14 52.8 0.3 6.4e-14 52.0 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EPY49287.1 - 1.1e-06 28.1 0.0 2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EPY49287.1 - 0.016 14.3 0.0 0.052 12.7 0.0 1.7 1 1 0 2 2 2 0 Sulfatase CRT10 PF08728.5 EPY49288.1 - 5.2e-15 54.5 6.2 2.5e-07 29.1 0.1 3.2 2 1 0 2 2 2 2 CRT10 WD40 PF00400.27 EPY49288.1 - 3.2e-08 33.1 2.9 4.7e-08 32.6 0.0 2.8 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF3402 PF11882.3 EPY49289.1 - 3.2e-63 214.1 8.6 5e-63 213.5 5.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EPY49289.1 - 3.7e-40 137.6 5.9 8.8e-40 136.3 1.8 2.3 2 0 0 2 2 2 1 N1221-like protein FA_hydroxylase PF04116.8 EPY49290.1 - 8.3e-11 42.2 20.3 8.3e-11 42.2 14.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2404 PF10296.4 EPY49292.1 - 0.00015 21.7 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RNase_T PF00929.19 EPY49293.1 - 5.4e-18 65.8 0.0 7.8e-17 62.0 0.0 2.1 1 1 0 1 1 1 1 Exonuclease SAP PF02037.22 EPY49293.1 - 0.0022 17.4 0.6 0.0051 16.2 0.4 1.6 1 0 0 1 1 1 1 SAP domain DUF2666 PF10869.3 EPY49293.1 - 0.04 13.9 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Tfb4 PF03850.9 EPY49294.1 - 1.2e-97 326.5 0.6 1.4e-97 326.3 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EPY49294.1 - 0.0051 16.9 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain GIDA PF01134.17 EPY49295.1 - 3.5e-145 483.7 0.0 4.2e-145 483.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EPY49295.1 - 8.2e-15 54.6 0.0 2.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EPY49295.1 - 2.4e-07 30.8 0.2 4.8e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPY49295.1 - 6.5e-06 25.4 0.0 8.7e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EPY49295.1 - 0.00054 18.9 1.7 0.48 9.2 0.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EPY49295.1 - 0.00095 18.7 0.3 0.0018 17.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EPY49295.1 - 0.00097 19.5 0.3 0.0026 18.1 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPY49295.1 - 0.0018 17.1 2.0 0.0041 16.0 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EPY49295.1 - 0.063 13.0 0.6 0.25 11.0 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPY49295.1 - 0.21 10.4 1.1 0.64 8.8 0.7 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EPY49295.1 - 0.46 8.8 3.3 0.42 9.0 0.5 2.1 3 0 0 3 3 3 0 HI0933-like protein CAS_CSE1 PF03378.10 EPY49296.1 - 9.5e-154 511.8 2.0 9.5e-154 511.8 1.4 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EPY49296.1 - 6.7e-149 495.4 7.6 1.1e-148 494.7 5.3 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EPY49296.1 - 1.1e-14 54.1 0.0 4e-14 52.2 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPY49296.1 - 0.001 19.0 0.1 0.031 14.1 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein ARID PF01388.16 EPY49297.1 - 3.3e-18 65.3 0.0 3.3e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Mcm10 PF09332.6 EPY49297.1 - 0.032 13.6 5.9 0.056 12.7 4.1 1.3 1 0 0 1 1 1 0 Mcm10 replication factor LIM_bind PF01803.11 EPY49298.1 - 6.3e-61 205.5 0.2 6.3e-61 205.5 0.1 1.6 2 0 0 2 2 2 1 LIM-domain binding protein G-patch PF01585.18 EPY49299.1 - 1.3e-07 31.2 0.4 2.7e-07 30.2 0.3 1.6 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 EPY49299.1 - 0.0067 16.1 0.7 0.059 13.0 0.0 2.5 2 0 0 2 2 2 1 R3H domain DUF3654 PF12376.3 EPY49299.1 - 0.081 12.7 12.6 2.5 7.9 2.9 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3654) WSC PF01822.14 EPY49300.1 - 6.2e-10 38.8 6.6 6.2e-10 38.8 4.6 2.6 2 1 0 2 2 2 1 WSC domain TMEM154 PF15102.1 EPY49300.1 - 1.8e-06 27.7 0.0 1.8e-06 27.7 0.0 2.2 1 1 1 2 2 1 1 TMEM154 protein family SKG6 PF08693.5 EPY49300.1 - 4.4e-05 22.6 1.1 4.4e-05 22.6 0.8 2.7 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EPY49300.1 - 0.00016 20.0 0.0 0.00029 19.2 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF605 PF04652.11 EPY49300.1 - 0.0014 18.1 13.7 0.0017 17.8 9.5 1.1 1 0 0 1 1 1 1 Vta1 like DUF4448 PF14610.1 EPY49300.1 - 0.0048 16.3 0.1 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 EPY49300.1 - 0.0067 16.1 0.0 0.0092 15.6 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family PAP1 PF08601.5 EPY49300.1 - 0.031 13.9 18.3 0.04 13.5 12.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Adeno_E3_CR2 PF02439.10 EPY49300.1 - 0.13 11.8 5.2 0.23 11.0 3.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 EPY49300.1 - 0.17 11.5 0.2 0.35 10.5 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain CytochromB561_N PF09786.4 EPY49300.1 - 1.7 7.0 20.6 2.4 6.5 14.3 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal COQ7 PF03232.8 EPY49301.1 - 0.12 11.8 0.1 0.13 11.6 0.1 1.0 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Thioredoxin PF00085.15 EPY49302.1 - 1.3e-30 105.1 1.9 1.4e-17 63.2 0.2 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 EPY49302.1 - 8.9e-20 71.2 8.6 1.6e-10 41.0 0.1 4.1 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPY49302.1 - 4.6e-06 26.6 7.8 0.11 12.6 0.0 4.5 4 1 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EPY49302.1 - 6.3e-05 23.1 6.4 0.46 10.6 0.3 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPY49302.1 - 0.003 17.3 0.2 3.4 7.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin domain HyaE PF07449.6 EPY49302.1 - 0.11 12.3 0.0 16 5.4 0.0 2.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE WD40 PF00400.27 EPY49303.1 - 4.8e-70 229.1 21.4 1e-08 34.7 0.0 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EPY49303.1 - 1.6e-18 66.6 0.1 3.3e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EPY49303.1 - 1.7e-05 23.7 0.3 1.1 7.9 0.0 4.7 2 2 1 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 EPY49303.1 - 0.00029 19.1 3.6 0.82 7.7 0.0 4.9 4 1 0 4 4 4 2 Nucleoporin Nup120/160 zf-C3HC4_3 PF13920.1 EPY49304.1 - 5.7e-11 41.9 6.4 9.5e-11 41.2 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY49304.1 - 7.8e-11 41.6 6.5 7.8e-11 41.6 4.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EPY49304.1 - 5.9e-10 38.6 8.0 1.2e-09 37.6 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY49304.1 - 9.4e-09 35.1 8.2 9.4e-09 35.1 5.7 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY49304.1 - 3.3e-08 33.1 7.4 6.1e-08 32.2 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPY49304.1 - 0.00012 21.8 0.5 0.0002 21.1 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPY49304.1 - 0.00065 19.5 9.2 0.0014 18.4 6.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPY49304.1 - 0.0028 17.1 5.0 0.0061 16.1 3.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EPY49304.1 - 0.014 15.0 3.0 0.014 15.0 2.1 2.3 2 1 1 3 3 3 0 RING-type zinc-finger zf-Nse PF11789.3 EPY49304.1 - 0.031 13.8 2.7 0.053 13.0 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4393 PF14337.1 EPY49304.1 - 0.06 12.7 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Baculo_IE-1 PF05290.6 EPY49304.1 - 0.075 12.7 2.7 0.12 12.1 1.9 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.1 EPY49304.1 - 0.075 12.8 4.7 0.14 11.9 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EPY49304.1 - 0.082 13.0 5.0 0.26 11.4 3.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EPY49304.1 - 0.19 11.2 6.6 0.99 8.9 4.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 EPY49304.1 - 0.37 10.6 6.3 0.75 9.6 4.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon Exo_endo_phos PF03372.18 EPY49305.1 - 2.2e-19 70.4 0.0 3.1e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EPY49305.1 - 1.1e-12 47.5 0.0 3.5e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EPY49305.1 - 7.6e-06 25.7 7.7 9.9e-05 22.1 2.8 3.4 2 1 0 2 2 2 1 GRF zinc finger CBFD_NFYB_HMF PF00808.18 EPY49306.1 - 1.6e-10 40.8 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPY49306.1 - 3.6e-05 23.7 0.0 6.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PUA PF01472.15 EPY49306.1 - 0.051 13.2 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 PUA domain Bromo_TP PF07524.8 EPY49306.1 - 0.068 12.9 0.2 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Bromodomain associated Lge1 PF11488.3 EPY49306.1 - 2.8 8.2 7.1 6.7 6.9 4.9 2.0 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 LSM PF01423.17 EPY49307.1 - 1.1e-14 53.7 1.0 1.5e-14 53.2 0.7 1.2 1 0 0 1 1 1 1 LSM domain PIGA PF08288.7 EPY49308.1 - 1.2e-44 150.5 1.5 1.2e-44 150.5 1.0 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EPY49308.1 - 2.3e-31 108.5 0.0 3.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPY49308.1 - 5.9e-15 55.4 0.3 1.2e-14 54.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EPY49308.1 - 8.7e-15 55.0 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPY49308.1 - 2.9e-13 50.2 0.0 4.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EPY49308.1 - 0.00055 19.7 1.1 0.0098 15.7 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EPY49308.1 - 0.0026 17.9 0.0 0.0065 16.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyl_synth PF14572.1 EPY49309.1 - 5.5e-39 133.8 3.1 2.3e-33 115.5 1.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EPY49309.1 - 4.7e-33 113.3 0.0 6.9e-32 109.6 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EPY49309.1 - 2.3e-11 43.5 0.2 5.3e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPY49309.1 - 0.0046 16.1 0.2 0.0085 15.3 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CTP_transf_1 PF01148.15 EPY49310.1 - 1.4e-20 74.1 7.6 3.8e-18 66.0 3.6 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family MAD PF05557.8 EPY49311.1 - 7.5e-111 371.4 75.5 8.8e-111 371.2 52.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein VRR_NUC PF08774.6 EPY49311.1 - 0.037 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 VRR-NUC domain bZIP_1 PF00170.16 EPY49311.1 - 0.13 12.2 0.1 0.13 12.2 0.1 10.1 7 2 3 10 10 10 0 bZIP transcription factor MxiH PF09392.5 EPY49311.1 - 6.4 7.4 9.1 14 6.3 5.3 2.5 1 1 1 2 2 2 0 Type III secretion needle MxiH like Ribosomal_S25 PF03297.10 EPY49312.1 - 1.3e-34 118.3 1.2 1.5e-34 118.2 0.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EPY49312.1 - 0.14 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Ftsk gamma domain Lactamase_B_2 PF12706.2 EPY49313.1 - 5.1e-32 111.0 0.2 9e-32 110.1 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPY49313.1 - 5.2e-09 36.0 0.0 9.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EPY49313.1 - 6.1e-08 32.0 0.0 1.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_3 PF13483.1 EPY49313.1 - 0.068 12.8 0.3 0.15 11.7 0.2 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain But2 PF09792.4 EPY49314.1 - 2.8e-34 117.9 1.5 4.9e-34 117.1 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Peptidase_S3 PF00944.14 EPY49314.1 - 0.065 12.6 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Alphavirus core protein Reticulon PF02453.12 EPY49315.1 - 3.1e-31 108.2 4.7 4.5e-31 107.7 3.2 1.2 1 0 0 1 1 1 1 Reticulon Patched PF02460.13 EPY49315.1 - 0.0038 15.2 0.4 0.0058 14.6 0.3 1.2 1 0 0 1 1 1 1 Patched family DUF1098 PF06497.6 EPY49315.1 - 0.066 13.2 3.4 0.53 10.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Pex24p PF06398.6 EPY49315.1 - 0.39 9.4 6.0 0.057 12.2 1.3 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin MutH PF02976.10 EPY49316.1 - 0.017 14.9 0.8 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 DNA mismatch repair enzyme MutH Adap_comp_sub PF00928.16 EPY49317.1 - 1.4e-46 158.7 0.2 2.1e-46 158.1 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Nse5 PF08691.5 EPY49318.1 - 9.3e-06 24.4 2.0 9.2e-05 21.1 0.0 2.4 2 1 0 2 2 2 1 DNA repair proteins Nse5 and Nse6 Lentiviral_Tat PF02998.9 EPY49318.1 - 0.027 14.2 0.2 7.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Lentiviral Tat protein ENTH PF01417.15 EPY49318.1 - 1.2 9.0 4.5 8.3 6.2 0.0 2.8 3 0 0 3 3 3 0 ENTH domain Plus-3 PF03126.13 EPY49319.1 - 7.5e-35 119.2 0.0 2.2e-34 117.7 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain FAP PF07174.6 EPY49319.1 - 0.0037 16.6 5.5 0.0055 16.0 3.8 1.2 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) CHD5 PF04420.9 EPY49319.1 - 2.8 7.5 5.6 0.5 10.0 0.8 2.1 2 0 0 2 2 2 0 CHD5-like protein FUSC PF04632.7 EPY49319.1 - 8.3 4.7 6.2 13 4.0 4.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family RNA_pol_Rpb1_1 PF04997.7 EPY49320.1 - 6.1e-98 328.1 0.0 8.7e-98 327.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EPY49320.1 - 3.5e-95 318.4 0.7 5.5e-95 317.7 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPY49320.1 - 5.8e-67 224.7 0.0 1.1e-66 223.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPY49320.1 - 5.7e-40 136.6 0.0 1.1e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPY49320.1 - 2.6e-32 110.7 0.0 6.7e-32 109.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 EPY49320.1 - 0.0095 15.4 0.1 0.026 13.9 0.0 1.7 1 0 0 1 1 1 1 InsA N-terminal domain Med11 PF10280.4 EPY49321.1 - 0.0051 16.8 2.0 0.0057 16.6 0.4 1.8 2 0 0 2 2 2 1 Mediator complex protein IncA PF04156.9 EPY49322.1 - 0.25 10.9 2.8 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 IncA protein EAP30 PF04157.11 EPY49324.1 - 2.8e-49 167.2 0.0 3.2e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4279 PF14106.1 EPY49324.1 - 0.0075 16.1 0.1 0.022 14.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4279) DUF4116 PF13475.1 EPY49324.1 - 0.056 12.9 0.0 0.18 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) RabGAP-TBC PF00566.13 EPY49325.1 - 1.6e-27 96.4 5.1 2.1e-27 96.0 3.5 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CN_hydrolase PF00795.17 EPY49326.1 - 6.2e-28 97.4 0.0 1.3e-27 96.3 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NOGCT PF08155.6 EPY49327.1 - 3.8e-28 96.9 0.2 8e-28 95.9 0.1 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EPY49327.1 - 1.6e-26 91.8 0.2 3e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EPY49327.1 - 1.2e-15 57.4 0.0 2.5e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY49327.1 - 8e-09 34.9 0.1 1.6e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 EPY49327.1 - 0.007 15.4 0.2 0.05 12.6 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EPY49327.1 - 0.0089 15.8 0.8 4.9 6.9 0.0 2.9 2 1 1 3 3 3 2 Dynamin family Miro PF08477.8 EPY49327.1 - 0.015 15.7 0.0 0.045 14.2 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EPY49327.1 - 0.019 15.1 0.6 2.2 8.4 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF258 PF03193.11 EPY49327.1 - 0.043 13.0 0.0 0.44 9.7 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EPY49327.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_pol_I_TF PF04090.7 EPY49328.1 - 5.7e-36 123.6 0.1 7.4e-36 123.2 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Apc3 PF12895.2 EPY49328.1 - 0.00091 19.3 0.4 0.34 11.0 0.1 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPY49328.1 - 0.035 14.7 1.5 1.2 9.8 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY49328.1 - 0.043 14.4 0.5 18 6.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY49328.1 - 0.093 13.2 0.3 1.5 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 EPY49329.1 - 5.7e-14 52.2 2.4 3.4e-08 33.6 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPY49329.1 - 3e-12 46.7 2.5 0.00011 22.6 0.0 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EPY49329.1 - 2.3e-10 39.7 2.8 1.9e-06 27.3 0.3 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EPY49329.1 - 5.9e-08 32.2 3.1 0.00022 21.1 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 EPY49329.1 - 9.7e-08 32.0 4.5 0.0055 16.9 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EPY49329.1 - 5.2e-05 22.8 0.1 0.00038 20.0 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Pribosyltran PF00156.22 EPY49330.1 - 4.7e-15 55.4 0.0 7.9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPY49330.1 - 0.023 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF619 PF04768.8 EPY49331.1 - 3.3e-53 179.5 0.0 7.4e-53 178.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Sld5 PF05916.6 EPY49332.1 - 5.4e-21 74.9 1.9 9.4e-21 74.1 1.3 1.4 1 0 0 1 1 1 1 GINS complex protein Lant_dehyd_C PF04738.8 EPY49332.1 - 0.015 13.5 0.3 0.02 13.1 0.2 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus Nbl1_Borealin_N PF10444.4 EPY49333.1 - 6.7e-19 67.0 1.1 1.2e-18 66.2 0.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DNA_binding_2 PF13724.1 EPY49333.1 - 0.083 13.0 0.3 0.29 11.3 0.2 1.9 1 0 0 1 1 1 0 DNA-binding domain CBFB_NFYA PF02045.10 EPY49334.1 - 6.8e-29 100.1 6.3 1.2e-28 99.4 4.3 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TspO_MBR PF03073.10 EPY49335.1 - 2.9e-33 114.4 10.8 3.4e-33 114.2 7.5 1.0 1 0 0 1 1 1 1 TspO/MBR family BAR PF03114.13 EPY49336.1 - 2.9e-58 197.1 0.5 3.6e-58 196.7 0.3 1.1 1 0 0 1 1 1 1 BAR domain ARS2 PF04959.8 EPY49337.1 - 1.7e-10 41.4 0.6 4.2e-10 40.1 0.1 2.0 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.3 EPY49337.1 - 1.9e-07 31.0 2.8 7.4e-07 29.1 1.9 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) TPR_11 PF13414.1 EPY49338.1 - 5.8e-17 61.0 4.7 1.4e-09 37.4 0.0 4.4 2 2 2 4 4 4 3 TPR repeat TPR_2 PF07719.12 EPY49338.1 - 3.6e-13 48.3 4.0 0.00018 21.1 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY49338.1 - 2.5e-12 45.8 5.4 0.00032 20.1 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPY49338.1 - 1.1e-10 41.2 0.1 0.13 12.9 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPY49338.1 - 2e-09 36.8 3.6 0.0076 16.3 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY49338.1 - 3.4e-09 37.1 0.2 0.0043 17.6 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY49338.1 - 3.6e-07 30.0 2.7 0.00039 20.3 0.0 4.3 2 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY49338.1 - 4.5e-06 26.8 1.5 0.29 11.5 0.0 4.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPY49338.1 - 5.9e-06 26.0 0.0 0.33 10.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EPY49338.1 - 9e-06 25.7 3.8 0.0082 16.2 0.4 3.3 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EPY49338.1 - 0.00011 21.7 6.4 0.96 9.3 0.0 5.5 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY49338.1 - 0.002 17.8 1.4 10 6.1 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EPY49338.1 - 0.0023 18.0 0.2 4 7.6 0.0 3.5 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPY49338.1 - 0.015 15.6 1.2 0.7 10.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 EPY49339.1 - 1.8e-51 174.7 0.0 2e-31 109.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49339.1 - 2.2e-19 69.5 0.0 9e-13 47.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EPY49339.1 - 0.0051 16.5 0.0 0.26 10.9 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY49339.1 - 0.0067 15.4 0.0 0.42 9.5 0.0 2.5 2 0 0 2 2 2 1 Kinase-like TPP_enzyme_N PF02776.13 EPY49340.1 - 2.8e-45 153.8 0.3 1.4e-44 151.5 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPY49340.1 - 9.6e-33 112.8 0.0 2e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPY49340.1 - 7.9e-23 80.7 0.0 1.5e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPY49340.1 - 0.12 11.2 0.1 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Phosphodiest PF01663.17 EPY49341.1 - 3.2e-85 286.6 0.5 3.9e-85 286.3 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPY49341.1 - 7e-08 32.0 0.2 7.5e-06 25.3 0.1 2.4 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EPY49341.1 - 0.033 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily VWA_2 PF13519.1 EPY49341.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Pyridox_oxase_2 PF12766.2 EPY49342.1 - 1.2e-19 70.4 0.0 2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Hpt PF01627.18 EPY49343.1 - 5.8e-14 51.8 0.0 9.1e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Hpt domain DUF2779 PF11074.3 EPY49343.1 - 0.025 14.6 0.4 0.079 12.9 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) RPOL_N PF14700.1 EPY49343.1 - 0.054 12.7 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal LXG PF04740.7 EPY49343.1 - 0.11 12.3 3.2 3 7.5 0.1 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily Aminotran_1_2 PF00155.16 EPY49344.1 - 4.1e-75 253.0 0.0 4.8e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II KH_1 PF00013.24 EPY49345.1 - 4.6e-38 128.6 2.3 5e-13 48.4 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPY49345.1 - 1.6e-28 97.8 3.6 1.3e-08 34.2 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPY49345.1 - 1e-12 47.4 0.2 0.00026 20.4 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPY49345.1 - 3.2e-07 29.8 0.1 0.35 10.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EPY49345.1 - 3.3e-06 26.7 0.3 4.2 7.2 0.0 4.3 4 0 0 4 4 4 3 NusA-like KH domain AAA PF00004.24 EPY49346.1 - 1.2e-41 141.9 0.0 2.3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPY49346.1 - 6.9e-07 29.3 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPY49346.1 - 1e-06 28.9 0.4 0.00024 21.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPY49346.1 - 2.1e-06 27.4 0.1 7.9e-06 25.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EPY49346.1 - 1.1e-05 24.4 0.0 1.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EPY49346.1 - 3.4e-05 23.9 0.2 9.3e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EPY49346.1 - 0.0002 20.5 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPY49346.1 - 0.00023 21.1 0.4 0.0011 18.9 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EPY49346.1 - 0.00095 19.0 0.0 0.003 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPY49346.1 - 0.0017 19.1 0.5 0.0065 17.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPY49346.1 - 0.002 17.5 1.2 0.22 10.9 0.3 2.6 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 EPY49346.1 - 0.0037 16.4 0.9 0.41 9.7 0.1 2.6 2 1 1 3 3 3 1 KaiC IstB_IS21 PF01695.12 EPY49346.1 - 0.0049 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EPY49346.1 - 0.0061 16.4 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPY49346.1 - 0.0064 16.2 0.3 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EPY49346.1 - 0.0097 15.3 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EPY49346.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPY49346.1 - 0.015 15.6 0.1 0.044 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EPY49346.1 - 0.016 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EPY49346.1 - 0.025 14.7 0.0 0.086 13.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.17 EPY49346.1 - 0.03 13.2 0.0 0.056 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 EPY49346.1 - 0.037 12.7 0.0 0.071 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EPY49346.1 - 0.049 12.7 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EPY49346.1 - 0.054 13.0 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPY49346.1 - 0.079 12.6 0.8 0.33 10.5 0.1 2.3 3 0 0 3 3 3 0 NACHT domain Sigma54_activ_2 PF14532.1 EPY49346.1 - 0.084 12.9 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 EPY49346.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) His_Phos_2 PF00328.17 EPY49347.1 - 5.6e-36 124.5 0.0 6.9e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-UBR PF02207.15 EPY49348.1 - 1.4e-13 50.3 14.7 1.4e-13 50.3 10.2 3.6 2 1 1 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EPY49348.1 - 6e-06 25.8 7.0 6e-06 25.8 4.8 2.9 2 0 0 2 2 2 1 PHD-finger DUF692 PF05114.8 EPY49348.1 - 0.025 13.5 0.1 0.044 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF692) MCM PF00493.18 EPY49349.1 - 4.1e-138 459.7 0.0 5.5e-138 459.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EPY49349.1 - 4.1e-31 108.0 24.2 4.1e-31 108.0 16.7 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EPY49349.1 - 2e-18 67.0 0.0 5.1e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPY49349.1 - 6.3e-09 35.2 0.0 2.4e-07 30.1 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPY49349.1 - 1e-06 28.5 0.0 2.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPY49349.1 - 0.00019 21.0 0.1 0.001 18.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPY49349.1 - 0.0017 17.8 0.1 0.0083 15.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EPY49349.1 - 0.019 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sec23_trunk PF04811.10 EPY49350.1 - 3.7e-64 216.4 0.0 5.2e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPY49350.1 - 2.2e-18 65.5 0.2 4.2e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPY49350.1 - 3.3e-17 62.7 0.0 8.1e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPY49350.1 - 1.2e-14 53.5 1.3 2.3e-14 52.6 0.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPY49350.1 - 3e-08 33.2 0.0 7.6e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DUF2410 PF10307.4 EPY49351.1 - 3.3e-64 215.9 0.2 4.5e-64 215.4 0.1 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Botulinum_HA-17 PF05588.6 EPY49351.1 - 0.019 14.8 0.6 8.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Clostridium botulinum HA-17 protein Fig1 PF12351.3 EPY49352.1 - 6.5e-13 48.9 19.3 8.6e-13 48.5 9.3 2.4 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Clc-like PF07062.7 EPY49352.1 - 0.43 9.7 6.5 0.28 10.4 3.3 1.6 1 1 0 1 1 1 0 Clc-like SUR7 PF06687.7 EPY49352.1 - 0.83 9.1 22.0 16 4.9 15.2 2.5 1 1 0 1 1 1 0 SUR7/PalI family WD40 PF00400.27 EPY49353.1 - 2.4e-23 81.0 18.1 8.5e-09 34.9 0.0 9.6 10 0 0 10 10 10 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPY49353.1 - 0.044 13.2 0.0 72 2.9 0.0 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.22 EPY49354.1 - 6.7e-58 195.2 0.4 6.7e-58 195.2 0.3 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPY49354.1 - 2e-32 111.2 0.0 5e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EPY49354.1 - 1.6e-31 107.9 0.0 3.5e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EPY49354.1 - 1.4e-22 79.3 0.0 5.6e-22 77.4 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPY49354.1 - 1.3e-11 44.4 0.2 4.1e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Sec66 PF09802.4 EPY49355.1 - 1.2e-42 145.4 0.2 1.4e-42 145.2 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SHR3_chaperone PF08229.6 EPY49356.1 - 5.5e-45 152.7 4.3 7.1e-45 152.3 3.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 AA_permease_2 PF13520.1 EPY49356.1 - 0.014 13.9 8.4 0.014 13.9 5.4 1.3 1 1 0 1 1 1 0 Amino acid permease Tom37_C PF11801.3 EPY49357.1 - 2.6e-18 66.4 0.2 2.6e-18 66.4 0.1 2.2 3 0 0 3 3 3 1 Tom37 C-terminal domain Tom37 PF10568.4 EPY49357.1 - 5.7e-15 55.3 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EPY49357.1 - 3.3e-05 23.6 0.0 8.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY49357.1 - 0.00045 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAP2 PF01569.16 EPY49358.1 - 3.2e-24 85.0 0.4 5.3e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EPY49358.1 - 0.047 13.2 0.0 0.089 12.3 0.0 1.4 1 1 0 1 1 1 0 PAP2 superfamily DUF4131 PF13567.1 EPY49358.1 - 0.05 13.0 3.2 1.3 8.4 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF1769 PF08588.5 EPY49359.1 - 7e-22 77.1 0.3 1.3e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Saw1 PF11561.3 EPY49360.1 - 1.1e-05 24.9 4.2 0.016 14.5 0.2 3.0 1 1 2 3 3 3 3 Single strand annealing-weakened 1 WGG PF10273.4 EPY49361.1 - 4.2e-24 84.4 0.4 7.8e-24 83.5 0.2 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 EPY49361.1 - 0.0034 17.4 0.9 0.0083 16.1 0.7 1.6 1 1 1 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Ribosomal_S17 PF00366.15 EPY49362.1 - 2.3e-14 53.1 1.1 2.8e-14 52.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DMRL_synthase PF00885.14 EPY49363.1 - 2.2e-44 150.6 0.0 2.6e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Stn1 PF10451.4 EPY49365.1 - 1.9e-23 82.6 0.2 2.7e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 EPY49365.1 - 5.9e-06 26.1 0.0 4.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Telomere capping C-terminal wHTH RseC_MucC PF04246.7 EPY49365.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC SAICAR_synt PF01259.13 EPY49367.1 - 1.8e-89 299.1 0.0 2.1e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase MIS13 PF08202.6 EPY49368.1 - 1.1e-57 195.3 14.3 1.6e-57 194.8 9.9 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF2951 PF11166.3 EPY49368.1 - 0.064 13.1 0.9 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) GrpE PF01025.14 EPY49368.1 - 0.7 9.4 4.2 12 5.3 0.3 2.4 2 0 0 2 2 2 0 GrpE DUF4482 PF14818.1 EPY49368.1 - 2.1 8.9 14.6 0.15 12.7 1.3 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4482) MFS_1 PF07690.11 EPY49369.1 - 2.8e-35 121.6 33.7 2.8e-35 121.6 23.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY49369.1 - 3e-08 32.6 29.7 1.7e-07 30.2 20.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3464 PF11947.3 EPY49369.1 - 0.16 11.3 2.0 4.1 6.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) Pkinase PF00069.20 EPY49372.1 - 9e-56 188.8 0.0 1.2e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49372.1 - 1.2e-37 129.4 0.0 1.6e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49372.1 - 1.8e-06 27.1 0.0 5.5e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EPY49372.1 - 0.0081 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EPY49372.1 - 0.079 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPY49372.1 - 0.19 10.4 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_C12 PF01088.16 EPY49373.1 - 6.1e-68 228.1 0.0 8.8e-68 227.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1542 PF07564.6 EPY49373.1 - 0.0071 16.3 1.7 0.013 15.5 0.3 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1542) Skp1 PF01466.14 EPY49374.1 - 8e-38 128.3 1.7 9.1e-38 128.1 0.2 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EPY49374.1 - 9.1e-26 89.7 0.2 2e-25 88.6 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4160 PF13711.1 EPY49374.1 - 0.087 12.6 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) DUF4375 PF14300.1 EPY49374.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Mis12 PF05859.7 EPY49375.1 - 1.7e-33 115.4 0.2 3e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Mis12 protein GAS PF13851.1 EPY49375.1 - 0.08 12.1 4.3 0.34 10.0 3.0 2.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TcdA_TcdB PF12919.2 EPY49375.1 - 0.086 11.3 0.5 0.12 10.8 0.3 1.3 1 1 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Swi5 PF07061.6 EPY49376.1 - 8.4e-25 86.3 1.6 8.9e-25 86.2 1.1 1.0 1 0 0 1 1 1 1 Swi5 Tropomyosin_1 PF12718.2 EPY49376.1 - 0.0068 16.2 3.5 0.0073 16.1 2.4 1.3 1 1 0 1 1 1 1 Tropomyosin like Mei5 PF10376.4 EPY49376.1 - 0.013 15.0 0.8 0.015 14.8 0.5 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein ORF11CD3 PF10549.4 EPY49376.1 - 0.022 14.4 1.0 0.049 13.3 0.7 1.7 1 0 0 1 1 1 0 ORF11CD3 domain YlqD PF11068.3 EPY49376.1 - 0.027 14.4 4.5 0.03 14.3 3.1 1.1 1 0 0 1 1 1 0 YlqD protein TipAS PF07739.8 EPY49376.1 - 0.032 14.5 0.2 0.037 14.3 0.1 1.1 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain KNOX2 PF03791.8 EPY49376.1 - 0.057 12.7 0.5 0.1 11.8 0.1 1.5 2 0 0 2 2 2 0 KNOX2 domain DUF892 PF05974.7 EPY49376.1 - 0.072 12.9 0.9 0.085 12.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF892) bZIP_1 PF00170.16 EPY49376.1 - 0.12 12.3 2.7 0.18 11.8 1.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor HrpB7 PF09486.5 EPY49376.1 - 0.17 11.8 2.9 0.63 9.9 1.1 1.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) M PF02370.11 EPY49376.1 - 0.22 11.9 9.7 0.28 11.6 3.8 2.5 1 1 1 2 2 2 0 M protein repeat Prefoldin_2 PF01920.15 EPY49376.1 - 0.22 11.2 5.8 0.13 11.9 2.4 1.7 2 0 0 2 2 2 0 Prefoldin subunit Cortex-I_coil PF09304.5 EPY49376.1 - 0.28 11.2 5.3 0.22 11.6 2.6 1.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil MSC PF09402.5 EPY49376.1 - 0.31 9.7 2.5 0.36 9.5 1.7 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain IncA PF04156.9 EPY49376.1 - 0.39 10.3 3.7 0.47 10.0 2.5 1.1 1 0 0 1 1 1 0 IncA protein DUF2681 PF10883.3 EPY49376.1 - 0.51 10.5 3.4 0.69 10.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Spore_SspJ PF09575.5 EPY49376.1 - 0.67 10.2 3.7 1.1 9.5 2.6 1.4 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Med4 PF10018.4 EPY49376.1 - 0.67 9.3 4.3 0.62 9.4 1.8 1.5 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4600 PF15372.1 EPY49376.1 - 1 9.6 5.1 2.3 8.4 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) bZIP_2 PF07716.10 EPY49376.1 - 1.3 8.8 5.7 2.4 8.0 4.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Nfu_N PF08712.6 EPY49377.1 - 2.7e-29 100.6 0.0 6.3e-29 99.4 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EPY49377.1 - 2.1e-22 78.6 0.0 3.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain IF4E PF01652.13 EPY49378.1 - 2.7e-54 183.1 0.3 3.2e-54 182.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mur_ligase_M PF08245.7 EPY49379.1 - 4.4e-06 26.8 1.1 0.0032 17.5 0.8 3.2 1 1 0 1 1 1 1 Mur ligase middle domain CPSF100_C PF13299.1 EPY49380.1 - 8.8e-35 120.2 0.1 2.3e-34 118.9 0.0 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EPY49380.1 - 2.4e-23 82.4 0.0 5.8e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EPY49380.1 - 1.4e-06 27.9 0.0 3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EPY49380.1 - 0.00034 20.2 0.1 0.00073 19.1 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPY49380.1 - 0.0027 17.4 0.1 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Transglut_core PF01841.14 EPY49381.1 - 2.9e-13 50.0 0.8 5.6e-13 49.0 0.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 EPY49381.1 - 1.3e-10 40.8 0.3 2.3e-10 40.0 0.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PhnA_Zn_Ribbon PF08274.7 EPY49381.1 - 0.0032 17.2 4.9 0.0099 15.6 3.4 1.8 1 0 0 1 1 1 1 PhnA Zinc-Ribbon SET PF00856.23 EPY49382.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Leu_zip PF15294.1 EPY49382.1 - 0.058 12.5 0.1 0.095 11.7 0.1 1.3 1 0 0 1 1 1 0 Leucine zipper Drf_GBD PF06371.8 EPY49383.1 - 1.7e-14 53.5 3.1 3.9e-14 52.4 1.9 1.8 1 1 1 2 2 2 1 Diaphanous GTPase-binding Domain ING PF12998.2 EPY49384.1 - 3.2e-14 53.0 0.0 3.2e-14 53.0 0.0 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EPY49384.1 - 2.2e-09 36.8 8.1 5e-09 35.7 5.6 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EPY49384.1 - 0.00015 21.8 0.2 0.00044 20.3 0.1 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain GCD14 PF08704.5 EPY49384.1 - 0.012 15.0 0.2 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DegQ PF08181.6 EPY49384.1 - 0.13 12.0 0.0 0.75 9.5 0.0 2.2 1 1 0 1 1 1 0 DegQ (SacQ) family ORC6 PF05460.8 EPY49384.1 - 0.72 8.9 6.3 1 8.3 4.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PHD_2 PF13831.1 EPY49384.1 - 2.1 7.7 7.8 0.22 10.8 2.3 1.7 2 0 0 2 2 2 0 PHD-finger RRF PF01765.14 EPY49385.1 - 7.6e-24 84.0 4.9 7.6e-24 84.0 3.4 2.1 2 0 0 2 2 2 1 Ribosome recycling factor SF-assemblin PF06705.6 EPY49385.1 - 0.013 14.6 7.3 0.15 11.2 1.2 2.2 2 0 0 2 2 2 0 SF-assemblin/beta giardin YlqD PF11068.3 EPY49385.1 - 0.018 15.0 10.6 0.023 14.7 1.3 2.2 2 0 0 2 2 2 0 YlqD protein Apolipoprotein PF01442.13 EPY49385.1 - 0.058 12.8 3.1 0.37 10.2 0.2 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain MutL_C PF08676.6 EPY49385.1 - 0.067 12.7 0.5 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 MutL C terminal dimerisation domain PIG-L PF02585.12 EPY49385.1 - 0.11 13.0 0.3 0.42 11.1 0.2 2.1 1 1 0 1 1 1 0 GlcNAc-PI de-N-acetylase Baculo_PEP_C PF04513.7 EPY49385.1 - 0.18 11.6 1.2 0.61 9.9 0.2 2.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tenui_NCP PF04876.7 EPY49385.1 - 0.33 10.4 5.2 0.63 9.5 0.7 2.3 2 1 0 2 2 2 0 Tenuivirus major non-capsid protein FCH PF00611.18 EPY49385.1 - 6.3 7.0 15.8 17 5.6 0.8 3.6 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain HMA PF00403.21 EPY49386.1 - 6.4e-09 35.8 0.5 7.4e-09 35.6 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Tox-PL-2 PF15643.1 EPY49386.1 - 0.0003 20.7 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 Papain fold toxin 2 DUF2100 PF09873.4 EPY49386.1 - 0.018 14.4 0.1 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) MafB19-deam PF14437.1 EPY49386.1 - 0.066 12.8 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase DUF1364 PF07102.7 EPY49386.1 - 0.077 12.8 0.0 0.086 12.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) Ras_bdg_2 PF14847.1 EPY49386.1 - 0.12 12.2 0.1 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Ras-binding domain of Byr2 CPSF_A PF03178.10 EPY49387.1 - 1.4e-85 287.2 0.1 1.4e-84 283.9 0.0 2.6 2 1 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EPY49387.1 - 4.3e-17 61.4 0.0 8.4e-17 60.4 0.0 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RNase_P_Rpp14 PF01900.14 EPY49388.1 - 0.00038 20.3 0.0 0.00047 20.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family adh_short PF00106.20 EPY49389.1 - 9.8e-08 32.0 0.0 1.9e-06 27.8 0.0 2.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPY49389.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KR domain LGT PF01790.13 EPY49389.1 - 0.046 12.6 0.1 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase Dus PF01207.12 EPY49390.1 - 1.6e-46 158.5 0.0 2.6e-46 157.8 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EPY49390.1 - 0.088 11.9 0.2 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI HSP70 PF00012.15 EPY49391.1 - 2.6e-239 795.1 9.0 2.9e-239 795.0 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPY49391.1 - 1.4e-17 63.3 0.9 1.6e-16 59.8 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPY49391.1 - 0.0081 15.7 0.0 0.025 14.2 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EPY49391.1 - 0.017 14.0 0.1 0.05 12.5 0.0 1.9 2 0 0 2 2 2 0 StbA protein Hydantoinase_A PF01968.13 EPY49391.1 - 0.024 13.7 0.2 0.066 12.3 0.1 1.8 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DDR PF08841.5 EPY49391.1 - 0.049 12.4 4.2 0.11 11.2 0.1 2.8 3 1 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Ribosomal_L14 PF00238.14 EPY49391.1 - 0.053 13.2 1.2 0.78 9.5 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein L14p/L23e FtsA PF14450.1 EPY49391.1 - 0.24 11.2 5.1 2.2 8.1 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Pro_isomerase PF00160.16 EPY49392.1 - 6.8e-48 162.7 0.2 7.6e-48 162.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3844 PF12955.2 EPY49393.1 - 2.5e-32 111.0 4.1 4e-32 110.3 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EPY49393.1 - 3.7 7.8 9.5 7.5 6.8 6.6 1.6 1 0 0 1 1 1 0 EGF-like domain tRNA-synt_1 PF00133.17 EPY49394.1 - 2.1e-214 712.9 0.4 1.6e-213 710.0 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPY49394.1 - 1e-33 116.2 0.7 2.4e-33 115.0 0.5 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPY49394.1 - 1.8e-19 69.6 3.3 5.5e-11 41.7 0.0 5.2 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EPY49394.1 - 7.6e-11 41.6 3.4 4.2e-07 29.4 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EPY49394.1 - 4.9e-05 22.3 0.7 0.0048 15.7 0.0 2.9 2 1 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EPY49394.1 - 0.00027 20.1 0.1 0.4 9.7 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.16 EPY49394.1 - 0.11 11.1 0.0 0.11 11.1 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Chitin_synth_1 PF01644.12 EPY49395.1 - 2e-51 174.0 0.2 3.5e-51 173.2 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPY49395.1 - 9.9e-16 57.2 0.0 2e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal PAH PF02671.16 EPY49396.1 - 3.7e-39 132.1 13.1 2e-15 56.1 0.0 4.7 4 0 0 4 4 4 4 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EPY49396.1 - 2.4e-22 78.5 0.1 6.8e-22 77.1 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Bromodomain PF00439.20 EPY49397.1 - 2.2e-43 146.0 7.1 1.3e-22 79.5 1.2 2.7 2 1 1 3 3 3 2 Bromodomain CKS PF01111.14 EPY49398.1 - 4.4e-33 112.9 0.1 6.1e-33 112.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ATP-synt PF00231.14 EPY49399.1 - 2.7e-67 227.1 7.4 3.1e-67 226.9 5.1 1.0 1 0 0 1 1 1 1 ATP synthase Vps53_N PF04100.7 EPY49399.1 - 0.015 14.1 1.6 0.13 11.0 0.0 2.2 2 1 0 2 2 2 0 Vps53-like, N-terminal DASH_Duo1 PF08651.5 EPY49399.1 - 0.11 12.1 3.2 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Duo1 Glyco_transf_22 PF03901.12 EPY49400.1 - 6.9e-33 114.2 33.4 9.7e-33 113.7 23.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Inhibitor_I78 PF11720.3 EPY49400.1 - 5.2e-09 35.7 0.0 8.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family DnaJ PF00226.26 EPY49401.1 - 2.3e-26 91.2 0.8 1.4e-25 88.8 1.2 1.8 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 EPY49401.1 - 3.1e-16 59.0 0.0 2.1e-15 56.3 0.0 2.4 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPY49401.1 - 3.9e-14 52.4 17.2 8e-14 51.4 11.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EPY49401.1 - 0.018 14.6 10.4 0.059 13.0 1.8 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family HECT_2 PF09814.4 EPY49402.1 - 4.4e-38 130.9 1.1 5.2e-38 130.6 0.8 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding UAA PF08449.6 EPY49403.1 - 1.1e-87 293.7 18.5 1.3e-87 293.5 12.9 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPY49403.1 - 4.2e-06 26.5 6.6 4.2e-06 26.5 4.6 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EPY49403.1 - 1.6e-05 24.9 27.2 0.00021 21.3 7.5 3.1 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EPY49403.1 - 0.0014 17.8 11.4 0.028 13.5 6.0 2.7 2 1 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EPY49403.1 - 0.0035 17.5 18.8 0.04 14.1 3.2 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter RE_ScaI PF09569.5 EPY49403.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 ScaI restriction endonuclease DUF4231 PF14015.1 EPY49403.1 - 2.2 8.3 7.3 0.12 12.3 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) VHS PF00790.14 EPY49404.1 - 6.1e-34 116.6 3.2 1.4e-33 115.4 2.2 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EPY49404.1 - 5.5e-17 60.8 1.6 9.4e-17 60.1 0.0 2.2 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EPY49404.1 - 2e-14 52.8 1.2 2.6e-14 52.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EPY49404.1 - 2.7e-12 45.9 0.1 1.7e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain UIM PF02809.15 EPY49404.1 - 0.00042 19.6 1.2 0.00042 19.6 0.8 2.5 3 0 0 3 3 3 1 Ubiquitin interaction motif DUF775 PF05603.7 EPY49404.1 - 0.031 13.8 0.3 0.089 12.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF775) TRAPPC-Trs85 PF12739.2 EPY49405.1 - 1.5e-81 274.2 3.6 2.1e-81 273.7 2.5 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit B2-adapt-app_C PF09066.5 EPY49405.1 - 0.031 14.1 0.3 0.12 12.2 0.2 2.0 1 1 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain zf-RING_2 PF13639.1 EPY49406.1 - 2e-08 33.8 16.5 3e-08 33.3 8.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPY49406.1 - 4.6e-08 32.9 11.9 4.6e-08 32.9 8.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EPY49406.1 - 6.5e-08 31.8 0.0 1.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.20 EPY49406.1 - 5.6e-07 29.1 10.7 5.6e-07 29.1 7.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY49406.1 - 6.7e-07 28.8 14.6 1.6e-06 27.6 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY49406.1 - 7.8e-07 28.7 15.9 2e-06 27.3 6.9 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EPY49406.1 - 1.4e-06 27.9 2.7 1.4e-06 27.9 1.9 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Sgf11 PF08209.6 EPY49406.1 - 2.3e-05 23.5 1.1 4.4e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C3HC4_4 PF15227.1 EPY49406.1 - 0.00016 21.4 11.5 0.00016 21.4 7.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PRP21_like_P PF12230.3 EPY49406.1 - 0.0011 18.5 0.7 0.0026 17.3 0.5 1.6 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein zf-rbx1 PF12678.2 EPY49406.1 - 0.014 15.5 10.5 0.019 15.0 4.6 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EPY49406.1 - 0.022 14.3 4.4 0.022 14.3 3.1 2.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SSFA2_C PF14723.1 EPY49406.1 - 0.04 13.6 1.6 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus zf-Di19 PF05605.7 EPY49406.1 - 0.042 13.9 0.3 0.042 13.9 0.2 2.9 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding Eapp_C PF10238.4 EPY49406.1 - 0.16 11.8 2.9 0.78 9.6 0.3 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-RING_UBOX PF13445.1 EPY49406.1 - 0.25 11.0 10.3 0.14 11.9 3.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger DZR PF12773.2 EPY49406.1 - 0.72 9.7 7.3 10 6.0 2.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.3 EPY49406.1 - 0.73 9.3 12.5 0.12 11.8 3.9 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zinc-ribbons_6 PF07191.7 EPY49406.1 - 1.4 8.7 10.0 4.3 7.2 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-C2H2_2 PF12756.2 EPY49406.1 - 7.7 6.6 7.2 2.2 8.4 0.1 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF1272 PF06906.6 EPY49406.1 - 8.4 6.3 9.6 2.9 7.8 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DnaJ PF00226.26 EPY49407.1 - 1.6e-12 46.9 0.1 3.6e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Anp1 PF03452.9 EPY49408.1 - 1.5e-112 375.1 0.0 2.2e-112 374.6 0.0 1.2 1 0 0 1 1 1 1 Anp1 Pterin_bind PF00809.17 EPY49409.1 - 2.6e-71 239.3 0.1 5.6e-71 238.2 0.0 1.6 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EPY49409.1 - 1.6e-41 141.0 0.0 3.2e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EPY49409.1 - 7.3e-33 113.1 0.0 2.5e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase CDC27 PF09507.5 EPY49410.1 - 2e-50 172.2 23.6 1.1e-28 100.7 12.1 2.0 1 1 1 2 2 2 2 DNA polymerase subunit Cdc27 DUF1507 PF07408.6 EPY49410.1 - 0.14 11.9 0.2 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) PEMT PF04191.8 EPY49411.1 - 6.3e-28 96.9 3.7 8e-28 96.6 1.6 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase NUC153 PF08159.7 EPY49412.1 - 1.5e-12 46.8 14.0 3.2e-11 42.6 0.8 3.8 3 0 0 3 3 3 3 NUC153 domain COQ7 PF03232.8 EPY49413.1 - 3.5e-72 241.4 0.0 4.1e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ldh_1_C PF02866.13 EPY49413.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain RNA_pol_Rpb4 PF03874.11 EPY49414.1 - 4.6e-23 81.4 0.0 5.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Gtr1_RagA PF04670.7 EPY49416.1 - 3e-99 330.8 0.4 3.7e-99 330.5 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EPY49416.1 - 2.1e-08 33.6 0.4 4.7e-08 32.5 0.0 1.8 3 0 0 3 3 3 1 Ras family MMR_HSR1 PF01926.18 EPY49416.1 - 1.6e-07 31.2 0.0 4.7e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EPY49416.1 - 1.6e-06 27.4 0.0 2.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPY49416.1 - 2.6e-06 27.9 0.0 9.1e-06 26.1 0.0 1.9 2 1 1 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EPY49416.1 - 2.5e-05 23.7 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF815 PF05673.8 EPY49416.1 - 0.0036 16.2 0.2 0.013 14.3 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 EPY49416.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EPY49416.1 - 0.014 14.9 0.1 0.032 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Imm42 PF15601.1 EPY49416.1 - 0.032 13.6 0.1 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 42 ABC_tran PF00005.22 EPY49416.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter zf-CCCH PF00642.19 EPY49417.1 - 1.6e-07 30.8 29.4 0.00017 21.1 0.8 5.2 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EPY49417.1 - 0.015 14.7 1.8 0.015 14.7 1.2 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 EPY49417.1 - 0.64 10.1 0.1 0.64 10.1 0.1 4.6 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type CIAPIN1 PF05093.8 EPY49418.1 - 2.3e-33 114.2 4.2 3.6e-33 113.6 2.9 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Erg28 PF03694.8 EPY49419.1 - 7.8e-39 132.1 2.3 9.7e-39 131.8 1.6 1.1 1 0 0 1 1 1 1 Erg28 like protein ubiquitin PF00240.18 EPY49420.1 - 1.3e-58 194.3 5.0 1.7e-34 117.0 0.6 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EPY49420.1 - 7.9e-33 111.9 2.8 6.2e-20 70.6 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPY49420.1 - 1.2e-09 38.2 0.8 2.5e-05 24.4 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPY49420.1 - 4.7e-07 29.6 0.1 0.0097 15.7 0.0 2.5 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EPY49420.1 - 1.4e-05 25.0 0.0 0.14 12.1 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2870) DUF2407 PF10302.4 EPY49420.1 - 2.3e-05 24.4 0.2 0.023 14.8 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 EPY49420.1 - 3.4e-05 23.6 0.2 0.00056 19.6 0.0 2.0 1 1 1 2 2 2 1 Telomere stability and silencing IGR PF09597.5 EPY49420.1 - 0.0018 18.1 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 2 IGR protein motif Plexin_cytopl PF08337.7 EPY49420.1 - 0.026 12.8 1.2 4.2 5.5 0.2 2.7 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain TUG-UBL1 PF11470.3 EPY49420.1 - 0.11 12.4 0.2 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Phage_pRha PF09669.5 EPY49420.1 - 0.13 12.5 0.1 2.4 8.5 0.0 2.1 1 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Peptidase_M14 PF00246.19 EPY49421.1 - 5.7e-64 216.4 0.0 7.6e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Cwf_Cwc_15 PF04889.7 EPY49422.1 - 4.6e-68 229.5 37.5 1.6e-67 227.7 26.0 1.7 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF663 PF04950.7 EPY49422.1 - 0.054 12.4 8.5 0.075 11.9 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF663) SR-25 PF10500.4 EPY49422.1 - 4.8 6.5 31.8 0.32 10.4 16.3 2.4 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein Astro_capsid PF03115.9 EPY49422.1 - 5.4 5.1 11.5 6.3 4.9 8.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 EPY49422.1 - 6.8 4.5 25.6 11 3.9 17.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Cpn60_TCP1 PF00118.19 EPY49423.1 - 6.8e-134 447.1 6.1 7.7e-134 446.9 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_5 PF07728.9 EPY49423.1 - 0.12 12.1 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.20 EPY49424.1 - 2.9e-42 144.6 0.0 3.5e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49424.1 - 4.1e-20 71.9 0.0 6.2e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49424.1 - 3e-05 23.1 0.1 0.3 10.0 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 EPY49424.1 - 0.021 13.8 0.0 0.056 12.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPY49424.1 - 0.11 12.1 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family CTD_bind PF04818.8 EPY49425.1 - 7.1e-18 64.6 0.5 5.8e-17 61.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EPY49425.1 - 0.012 15.2 0.4 0.028 14.0 0.0 1.9 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 Adaptin_N PF01602.15 EPY49426.1 - 1.3e-88 297.6 13.4 2.3e-88 296.8 9.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EPY49426.1 - 2.9e-57 191.9 0.0 7e-57 190.7 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EPY49426.1 - 3.4e-53 179.0 0.1 9.6e-53 177.6 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EPY49426.1 - 6.7e-09 35.9 1.2 6.6e-05 23.1 0.0 4.7 3 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.2 EPY49426.1 - 6.2e-06 26.1 4.0 0.014 15.2 1.1 4.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EPY49426.1 - 0.00026 20.7 0.0 0.89 9.7 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat ParcG PF10274.4 EPY49426.1 - 0.093 12.6 1.5 11 5.8 0.1 2.8 3 0 0 3 3 3 0 Parkin co-regulated protein Myosin_head PF00063.16 EPY49427.1 - 3.7e-225 749.1 4.1 5.9e-225 748.4 2.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EPY49427.1 - 1.2e-51 174.8 0.2 2.5e-51 173.8 0.1 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EPY49427.1 - 2.3e-13 49.3 1.0 9.9e-13 47.2 0.1 2.5 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EPY49427.1 - 2.1e-12 46.3 0.0 5.6e-11 41.8 0.0 3.2 4 0 0 4 4 4 1 Variant SH3 domain SH3_2 PF07653.12 EPY49427.1 - 1.4e-08 34.0 0.0 4.3e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EPY49427.1 - 0.0047 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPY49427.1 - 0.0094 15.0 0.0 0.027 13.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 EPY49427.1 - 0.012 16.4 0.0 0.037 14.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain SH3_3 PF08239.6 EPY49427.1 - 0.016 15.3 0.6 0.053 13.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Hpr_kinase_C PF07475.7 EPY49427.1 - 0.017 14.4 0.1 4.1 6.6 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TrwB_AAD_bind PF10412.4 EPY49427.1 - 0.042 12.4 0.0 0.069 11.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IQ PF00612.22 EPY49427.1 - 3.2 7.6 8.8 1.9 8.3 3.9 2.3 1 1 1 2 2 2 0 IQ calmodulin-binding motif FAD_binding_3 PF01494.14 EPY49428.1 - 5.2e-24 84.9 0.0 8.1e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EPY49428.1 - 1.3e-05 24.1 0.0 2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EPY49428.1 - 0.00012 21.0 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPY49428.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPY49428.1 - 0.0061 16.3 0.0 0.028 14.2 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPY49428.1 - 0.04 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPY49428.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPY49428.1 - 0.055 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Fasciclin PF02469.17 EPY49429.1 - 2.8e-06 27.3 0.5 4.8e-06 26.6 0.4 1.4 1 1 0 1 1 1 1 Fasciclin domain Sec23_helical PF04815.10 EPY49430.1 - 0.057 12.8 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Amino_oxidase PF01593.19 EPY49431.1 - 1.5e-43 149.5 0.0 3.9e-37 128.3 0.0 2.8 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.12 EPY49431.1 - 1.3e-12 47.6 0.0 4.5e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.14 EPY49431.1 - 2.6e-05 24.4 0.3 6.6e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box NAD_binding_8 PF13450.1 EPY49431.1 - 6.5e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPY49431.1 - 0.0022 16.9 0.0 0.0068 15.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPY49431.1 - 0.0026 17.8 0.0 0.5 10.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPY49431.1 - 0.0064 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPY49431.1 - 0.0066 16.2 0.1 0.44 10.2 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding HMG_box_2 PF09011.5 EPY49431.1 - 0.007 16.7 2.9 0.14 12.5 0.5 2.6 1 1 1 2 2 2 1 HMG-box domain Malic_M PF03949.10 EPY49431.1 - 0.062 12.8 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain RRM_1 PF00076.17 EPY49432.1 - 4.4e-27 93.5 4.1 6.7e-19 67.3 0.3 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49432.1 - 2.9e-19 68.8 0.4 3.2e-10 39.8 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49432.1 - 3e-19 68.6 0.2 4.2e-09 36.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EPY49432.1 - 0.00048 19.8 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4092 PF13322.1 EPY49432.1 - 0.038 13.7 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) RNA_bind PF08675.6 EPY49432.1 - 0.054 13.4 0.0 0.9 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain eIF-1a PF01176.14 EPY49433.1 - 3e-18 64.9 0.1 3.9e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3567 PF12091.3 EPY49433.1 - 0.047 13.6 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) VRR_NUC PF08774.6 EPY49434.1 - 1.5e-15 56.9 0.0 3.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain CWC25 PF12542.3 EPY49435.1 - 1.5e-20 73.4 3.6 1.5e-20 73.4 2.5 3.7 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EPY49435.1 - 2.9e-14 52.7 12.4 2.9e-14 52.7 8.6 5.5 3 2 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Evr1_Alr PF04777.8 EPY49436.1 - 2.6e-13 49.6 0.0 4.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family RPAP1_C PF08620.5 EPY49438.1 - 8e-29 99.3 0.0 1.7e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EPY49438.1 - 1.2e-08 34.4 3.2 2.3e-08 33.5 2.2 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 EPY49438.1 - 0.24 11.5 0.7 2.7 8.3 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat DUF4168 PF13767.1 EPY49439.1 - 1.2 9.8 14.3 6.2 7.5 0.0 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4168) V_ATPase_I PF01496.14 EPY49439.1 - 8.9 4.0 14.3 13 3.4 9.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA PF00004.24 EPY49440.1 - 2.6e-07 30.9 0.0 6.9e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY49440.1 - 0.0034 17.5 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY49440.1 - 0.047 13.6 0.0 0.16 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain zf-RING_2 PF13639.1 EPY49441.1 - 4.1e-11 42.5 6.5 1e-10 41.2 4.5 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPY49441.1 - 6.2e-09 35.8 2.3 1.2e-08 34.8 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPY49441.1 - 1.5e-06 27.7 4.7 3e-06 26.7 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY49441.1 - 1.2e-05 25.2 8.0 1.2e-05 25.2 2.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY49441.1 - 1.7e-05 24.4 7.5 0.005 16.4 4.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY49441.1 - 3.5e-05 23.4 8.7 0.00019 21.1 6.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPY49441.1 - 0.02 14.6 7.9 0.11 12.3 5.6 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EPY49441.1 - 4.8 6.7 6.6 11 5.5 4.6 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPY49441.1 - 5.2 6.8 9.6 30 4.4 6.6 2.4 1 1 0 1 1 1 0 RING-type zinc-finger HUN PF08729.5 EPY49442.1 - 7.5e-13 48.1 0.3 2.6e-12 46.4 0.2 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Mitofilin PF09731.4 EPY49442.1 - 7.4 5.0 23.5 8.7 4.8 16.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SURF6 PF04935.7 EPY49443.1 - 5.9e-43 146.6 58.5 9.9e-43 145.9 40.6 1.3 1 0 0 1 1 1 1 Surfeit locus protein 6 Lentiviral_Tat PF02998.9 EPY49443.1 - 0.44 10.3 8.9 0.078 12.8 2.5 2.3 2 1 0 2 2 2 0 Lentiviral Tat protein Adaptin_N PF01602.15 EPY49444.1 - 3.1e-141 471.2 10.4 4e-141 470.9 7.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EPY49444.1 - 6.6e-22 78.2 2.4 5.4e-21 75.2 0.0 3.2 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPY49444.1 - 2.5e-15 56.5 0.0 0.00036 20.7 0.0 4.6 2 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EPY49444.1 - 5.7e-10 38.4 0.4 0.023 14.7 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EPY49444.1 - 1.4e-06 28.5 0.6 0.2 12.1 0.0 4.8 5 0 0 5 5 5 2 HEAT-like repeat CLASP_N PF12348.3 EPY49444.1 - 0.035 13.4 1.3 1.3 8.2 0.0 3.0 3 1 0 3 3 3 0 CLASP N terminal AAA PF00004.24 EPY49445.1 - 2.5e-38 131.2 0.0 5e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPY49445.1 - 4.1e-08 32.9 0.0 3e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EPY49445.1 - 1.8e-07 31.3 0.2 1.5e-05 25.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPY49445.1 - 3.9e-06 26.0 0.0 6.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EPY49445.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EPY49445.1 - 0.00043 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EPY49445.1 - 0.00045 20.2 0.1 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 EPY49445.1 - 0.00049 18.9 0.1 0.0011 17.7 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 EPY49445.1 - 0.0008 19.1 0.1 0.0023 17.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPY49445.1 - 0.0021 18.8 0.0 0.0038 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPY49445.1 - 0.0029 16.5 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EPY49445.1 - 0.003 16.7 0.1 0.0059 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPY49445.1 - 0.0033 16.8 0.2 0.081 12.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EPY49445.1 - 0.0038 16.8 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPY49445.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EPY49445.1 - 0.0056 16.5 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPY49445.1 - 0.0099 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPY49445.1 - 0.018 14.6 0.1 0.11 12.1 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 EPY49445.1 - 0.03 14.6 0.1 0.092 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EPY49445.1 - 0.069 13.1 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 EPY49445.1 - 0.085 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EPY49445.1 - 0.11 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EPY49445.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 EPY49445.1 - 0.17 11.0 0.1 3 6.8 0.0 2.1 1 1 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EPY49445.1 - 0.18 10.8 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin polyprenyl_synt PF00348.12 EPY49446.1 - 5.9e-52 176.0 0.0 8.6e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Coatomer_WDAD PF04053.9 EPY49448.1 - 1.6e-136 455.6 10.5 1.6e-136 455.6 7.3 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EPY49448.1 - 2.4e-75 253.6 0.1 3.6e-75 253.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EPY49448.1 - 1.9e-57 189.2 13.3 8.4e-12 44.4 0.1 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPY49448.1 - 0.0021 16.2 3.7 0.45 8.5 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EPY49448.1 - 0.023 14.3 2.1 0.15 11.6 0.2 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS Prok-RING_1 PF14446.1 EPY49448.1 - 0.044 13.5 2.0 0.097 12.4 1.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 EPY49448.1 - 0.076 12.5 0.6 0.21 11.1 0.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Far-17a_AIG1 PF04750.9 EPY49449.1 - 2.1e-39 134.8 15.6 2.4e-39 134.6 10.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein UDP-g_GGTase PF06427.6 EPY49450.1 - 1.2e-56 191.3 0.1 4e-56 189.6 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EPY49450.1 - 4.9e-07 29.3 0.9 1.4e-06 27.8 0.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 Rpn3_C PF08375.6 EPY49451.1 - 2.7e-25 88.5 2.6 2.7e-25 88.5 1.8 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EPY49451.1 - 4.1e-20 72.0 0.2 1e-17 64.3 0.0 3.0 3 0 0 3 3 3 2 PCI domain PCI_Csn8 PF10075.4 EPY49451.1 - 0.0082 15.9 0.0 0.13 11.9 0.0 2.4 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 UQ_con PF00179.21 EPY49452.1 - 2.4e-52 176.0 0.0 2.7e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPY49452.1 - 8.6e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPY49452.1 - 0.0031 17.3 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EPY49452.1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain SCO1-SenC PF02630.9 EPY49454.1 - 1.4e-55 187.6 0.0 1.8e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EPY49454.1 - 0.00043 19.9 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Pkinase PF00069.20 EPY49455.1 - 7.3e-22 77.7 0.0 1.4e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EPY49455.1 - 7e-09 35.0 9.8 0.24 11.5 0.2 5.9 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 EPY49455.1 - 2.4e-08 33.4 0.0 3.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EPY49455.1 - 7.2e-07 29.3 0.1 0.034 14.4 0.0 4.6 2 1 1 3 3 3 2 HEAT repeats BBS2_N PF14781.1 EPY49455.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal APH PF01636.18 EPY49455.1 - 0.14 11.8 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EPY49456.1 - 4.7e-68 229.1 0.0 6e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49456.1 - 1.5e-31 109.4 0.0 2e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY49456.1 - 0.027 14.2 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mitochondr_Som1 PF11093.3 EPY49457.1 - 0.14 11.9 0.3 0.56 10.0 0.1 1.7 1 1 1 2 2 2 0 Mitochondrial export protein Som1 ORMDL PF04061.9 EPY49458.1 - 2.3e-58 195.5 6.9 2.7e-58 195.3 4.8 1.1 1 0 0 1 1 1 1 ORMDL family Arm PF00514.18 EPY49458.1 - 0.053 13.3 0.1 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Asn_synthase PF00733.16 EPY49459.1 - 3.5e-69 233.1 0.0 5.2e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPY49459.1 - 1.7e-39 134.4 0.0 2.7e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EPY49459.1 - 2.2e-33 115.0 0.0 4.2e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EPY49459.1 - 2.1e-08 33.6 0.0 4.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EPY49459.1 - 9.6e-05 21.2 0.0 0.02 13.5 0.0 2.5 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EPY49459.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Ribonuclease_3 PF00636.21 EPY49460.1 - 3.4e-20 72.5 1.2 9.4e-20 71.1 0.0 2.3 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPY49460.1 - 1.1e-18 67.3 0.0 2.1e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EPY49460.1 - 5.1e-09 36.5 0.0 1.1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif GRAB PF10375.4 EPY49461.1 - 2.4e-07 30.1 1.1 5.4e-07 28.9 0.7 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EPY49461.1 - 0.0015 17.8 15.0 0.018 14.2 5.6 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EPY49461.1 - 0.035 14.0 1.3 0.035 14.0 0.9 5.9 3 2 3 6 6 6 0 bZIP transcription factor Gp58 PF07902.6 EPY49461.1 - 1.4 7.0 17.2 1.8 6.6 7.3 2.1 1 1 1 2 2 2 0 gp58-like protein Nop PF01798.13 EPY49462.1 - 9.2e-47 158.1 0.0 2.1e-46 156.9 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EPY49462.1 - 5.2e-46 156.1 1.9 5.2e-46 156.1 1.3 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 EPY49462.1 - 7.3e-17 60.9 0.0 1.9e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain UPF0203 PF05254.7 EPY49463.1 - 5.4e-28 96.6 3.1 6e-28 96.4 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EPY49463.1 - 0.036 14.0 1.6 0.18 11.8 1.1 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EPY49463.1 - 0.064 13.0 3.6 0.41 10.4 2.5 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF19 PF01579.13 EPY49463.1 - 0.085 12.8 1.6 0.098 12.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF19) UCR_hinge PF02320.11 EPY49463.1 - 0.12 12.3 2.0 0.31 10.9 1.4 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Rad52_Rad22 PF04098.10 EPY49464.1 - 5.8e-59 198.2 0.0 8.4e-59 197.7 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ATP_bind_1 PF03029.12 EPY49465.1 - 1.9e-84 282.9 1.1 2.8e-84 282.3 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EPY49465.1 - 5.7e-08 32.4 0.1 7.7e-07 28.7 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EPY49465.1 - 6.4e-06 25.7 0.1 2.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EPY49465.1 - 9.3e-06 26.4 0.5 5.5e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EPY49465.1 - 1.2e-05 24.8 0.0 0.00019 20.9 0.0 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EPY49465.1 - 1.7e-05 24.3 0.0 0.0008 18.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 EPY49465.1 - 3.7e-05 24.2 0.5 0.08 13.4 0.0 2.8 3 0 0 3 3 2 2 Miro-like protein Arf PF00025.16 EPY49465.1 - 4e-05 22.9 0.0 0.017 14.3 0.0 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EPY49465.1 - 0.00011 22.3 0.0 0.00053 20.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPY49465.1 - 0.00012 22.0 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EPY49465.1 - 0.00026 19.8 0.1 0.36 9.5 0.0 2.5 2 1 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EPY49465.1 - 0.00037 20.4 0.1 0.00096 19.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EPY49465.1 - 0.0005 19.5 1.5 0.003 17.0 1.0 2.1 1 1 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 EPY49465.1 - 0.00058 19.5 0.1 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPY49465.1 - 0.00062 19.8 0.0 0.0019 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 EPY49465.1 - 0.00064 20.0 1.5 0.0034 17.6 0.0 2.7 3 1 0 3 3 2 1 AAA domain FeoB_N PF02421.13 EPY49465.1 - 0.00079 18.7 0.0 0.03 13.5 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.7 EPY49465.1 - 0.0008 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ras PF00071.17 EPY49465.1 - 0.0015 17.9 0.0 0.61 9.4 0.0 2.4 2 0 0 2 2 2 1 Ras family Zeta_toxin PF06414.7 EPY49465.1 - 0.0016 17.5 0.0 0.0046 16.0 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.5 EPY49465.1 - 0.0019 17.4 0.0 0.22 10.7 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.17 EPY49465.1 - 0.0022 16.9 0.4 0.0065 15.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain T2SE PF00437.15 EPY49465.1 - 0.0028 16.6 0.0 0.0073 15.2 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 EPY49465.1 - 0.0029 17.9 0.8 0.021 15.1 0.4 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EPY49465.1 - 0.0031 16.8 0.4 0.66 9.2 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_14 PF13173.1 EPY49465.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPY49465.1 - 0.0064 16.2 0.3 0.17 11.5 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase G-alpha PF00503.15 EPY49465.1 - 0.0066 15.1 3.8 0.0078 14.9 0.0 2.6 2 1 1 3 3 3 1 G-protein alpha subunit MobB PF03205.9 EPY49465.1 - 0.0069 16.1 0.1 0.018 14.7 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EPY49465.1 - 0.0069 15.8 0.1 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 EPY49465.1 - 0.0071 15.6 0.0 0.018 14.3 0.0 1.7 1 0 0 1 1 1 1 Poxvirus A32 protein Dynamin_N PF00350.18 EPY49465.1 - 0.0073 16.1 5.3 0.023 14.5 0.2 3.2 2 1 0 2 2 2 1 Dynamin family AAA_24 PF13479.1 EPY49465.1 - 0.008 15.7 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EPY49465.1 - 0.0086 15.5 0.1 0.079 12.4 0.0 2.5 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 EPY49465.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EPY49465.1 - 0.015 14.3 0.1 0.026 13.4 0.1 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 EPY49465.1 - 0.018 15.3 0.1 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter KTI12 PF08433.5 EPY49465.1 - 0.02 14.1 0.1 0.051 12.7 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EPY49465.1 - 0.024 14.3 0.0 0.14 11.8 0.0 2.1 1 1 0 1 1 1 0 NTPase AAA_25 PF13481.1 EPY49465.1 - 0.025 13.9 0.1 0.12 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPY49465.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 EPY49465.1 - 0.053 12.7 0.0 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 EPY49465.1 - 0.056 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EPY49465.1 - 0.5 10.3 2.2 0.97 9.3 0.0 2.5 3 1 0 3 3 2 0 AAA domain DUF2347 PF09804.4 EPY49466.1 - 8.2e-39 133.5 1.7 1.5e-38 132.7 1.2 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EPY49466.1 - 0.032 13.9 0.2 0.087 12.5 0.1 1.7 1 0 0 1 1 1 0 Stabilization of polarity axis M16C_assoc PF08367.6 EPY49467.1 - 3.6e-73 245.4 1.5 1.2e-72 243.8 0.3 2.1 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EPY49467.1 - 1.5e-32 112.7 1.5 4.1e-22 78.7 0.0 3.2 4 1 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPY49467.1 - 1.7e-07 31.0 0.0 1.2e-05 25.0 0.0 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Ribosomal_L38e PF01781.13 EPY49468.1 - 2.6e-35 119.9 2.9 2.9e-35 119.8 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.1 EPY49469.1 - 2.4e-22 79.6 0.0 3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPY49469.1 - 6.9e-09 35.7 0.0 1.2e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY49469.1 - 4.5e-08 32.7 0.0 9.6e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EPY49469.1 - 6.8e-07 29.2 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPY49469.1 - 0.003 17.5 0.1 0.025 14.5 0.0 2.0 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPY49469.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.7 EPY49469.1 - 0.038 12.4 0.0 0.08 11.3 0.0 1.4 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit Acetyltransf_10 PF13673.1 EPY49469.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FimP PF09766.4 EPY49470.1 - 1.3e-15 57.3 13.2 1.3e-15 57.3 9.2 1.3 2 0 0 2 2 2 1 Fms-interacting protein DUF91 PF01939.11 EPY49470.1 - 0.016 14.3 0.5 0.025 13.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF91 UxuA PF03786.8 EPY49470.1 - 0.02 13.4 0.2 0.023 13.2 0.2 1.1 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) EcKinase PF02958.15 EPY49470.1 - 0.1 11.6 6.3 0.13 11.3 4.4 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase FUSC PF04632.7 EPY49470.1 - 2 6.7 5.1 2.1 6.6 3.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C3HC PF07967.8 EPY49471.1 - 0.17 11.6 5.7 0.24 11.1 2.9 1.9 1 1 1 2 2 2 0 C3HC zinc finger-like SBDS_C PF09377.5 EPY49471.1 - 0.18 11.5 1.7 0.22 11.2 1.2 1.2 1 0 0 1 1 1 0 SBDS protein C-terminal domain ACOX PF01756.14 EPY49471.1 - 0.36 10.1 4.0 0.67 9.2 0.8 1.9 1 1 1 2 2 2 0 Acyl-CoA oxidase Phage_Mu_Gam PF07352.7 EPY49471.1 - 0.54 9.7 9.3 2.6 7.5 1.9 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Exonuc_VII_L PF02601.10 EPY49471.1 - 0.54 9.3 11.4 0.56 9.3 7.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RNA_GG_bind PF10258.4 EPY49471.1 - 0.59 9.8 4.4 0.87 9.3 0.4 2.5 1 1 2 3 3 3 0 PHAX RNA-binding domain OmpH PF03938.9 EPY49471.1 - 1.5 8.7 11.9 1.9 8.4 8.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 EPY49471.1 - 3.6 6.4 12.6 4.5 6.1 8.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4510 PF14971.1 EPY49471.1 - 3.8 7.6 8.6 2.4 8.3 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) DUF4140 PF13600.1 EPY49471.1 - 7.6 7.0 7.5 8.2 6.9 3.4 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PI3_PI4_kinase PF00454.22 EPY49472.1 - 9.4e-40 136.5 0.0 2.9e-39 134.9 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EPY49472.1 - 4.1e-18 65.2 0.0 1.3e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UCH PF00443.24 EPY49473.1 - 8.3e-29 100.5 0.4 1.3e-28 99.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPY49473.1 - 3e-11 43.2 0.7 3e-11 43.2 0.5 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EPY49473.1 - 0.00043 19.8 0.2 0.001 18.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PITH PF06201.8 EPY49474.1 - 2.8e-43 147.2 1.0 3.8e-43 146.8 0.7 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EPY49474.1 - 8.9e-26 89.5 0.0 1.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPY49474.1 - 3.2e-06 27.3 0.1 1.2e-05 25.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPY49474.1 - 7.3e-06 26.0 0.0 3e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Sad1_UNC PF07738.8 EPY49474.1 - 0.00053 19.7 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Thioredoxin_7 PF13899.1 EPY49474.1 - 0.003 17.5 0.1 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EPY49474.1 - 0.012 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.16 EPY49474.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family DSBA PF01323.15 EPY49474.1 - 0.089 12.3 0.7 0.45 10.0 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain F5_F8_type_C PF00754.20 EPY49474.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain HyaE PF07449.6 EPY49474.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE WD40 PF00400.27 EPY49475.1 - 1.5e-30 103.9 27.0 7.2e-12 44.7 0.7 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EPY49475.1 - 2.9e-05 23.8 0.1 0.0014 18.3 0.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPY49475.1 - 0.00033 18.9 0.8 0.3 9.1 0.0 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Proteasome PF00227.21 EPY49477.1 - 3.2e-23 81.9 0.0 3.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit MVIN PF03023.9 EPY49477.1 - 0.12 10.7 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 MviN-like protein 2-Hacid_dh_C PF02826.14 EPY49478.1 - 8.8e-54 181.3 0.0 1.3e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPY49478.1 - 4.6e-15 55.2 0.0 5.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPY49478.1 - 1.2e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EPY49478.1 - 1.9e-05 24.1 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EPY49478.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 EPY49478.1 - 0.002 18.5 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EPY49478.1 - 0.0049 16.9 0.0 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EPY49478.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EPY49478.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ParcG PF10274.4 EPY49478.1 - 0.093 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Parkin co-regulated protein Oxidored_FMN PF00724.15 EPY49479.1 - 7.2e-101 337.5 0.0 9.1e-101 337.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3074 PF11274.3 EPY49480.1 - 5.1e-26 91.4 0.0 8.6e-26 90.6 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) ATP_bind_4 PF01902.12 EPY49481.1 - 2.9e-39 134.7 0.0 8e-39 133.2 0.0 1.7 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EPY49481.1 - 1.6e-18 66.6 0.0 7.3e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Syja_N PF02383.13 EPY49482.1 - 9.7e-48 162.5 0.1 3.8e-47 160.6 0.0 2.0 2 1 1 3 3 3 1 SacI homology domain Exo_endo_phos PF03372.18 EPY49482.1 - 1.1e-21 77.8 0.1 1.9e-21 77.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ODC_AZ PF02100.12 EPY49483.1 - 2.1e-20 72.1 0.0 3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme SHNi-TPR PF10516.4 EPY49484.1 - 1.6e-13 49.6 4.4 1.4e-12 46.6 0.4 3.2 3 1 1 4 4 4 1 SHNi-TPR TPR_11 PF13414.1 EPY49484.1 - 1.3e-06 27.9 6.6 0.00041 19.9 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EPY49484.1 - 0.00044 19.9 9.6 0.007 16.2 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY49484.1 - 0.00044 20.1 6.0 0.34 10.8 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPY49484.1 - 0.0094 15.5 4.5 0.091 12.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Dabb PF07876.7 EPY49484.1 - 0.022 15.1 0.1 0.068 13.6 0.0 1.8 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain TPR_16 PF13432.1 EPY49484.1 - 0.033 14.8 2.8 5.4 7.8 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPY49484.1 - 1.1 9.6 8.2 14 6.0 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat H-kinase_dim PF02895.9 EPY49484.1 - 1.7 9.0 6.8 0.34 11.2 1.3 2.5 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain RabGAP-TBC PF00566.13 EPY49485.1 - 2.2e-52 177.6 0.6 3.2e-52 177.1 0.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1242 PF06842.7 EPY49486.1 - 1.8e-16 59.3 1.1 2.5e-16 58.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) BAG PF02179.11 EPY49487.1 - 1.8e-15 56.7 0.1 3.9e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EPY49487.1 - 0.0056 16.0 0.2 0.061 12.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Fungal_trans PF04082.13 EPY49489.1 - 5e-27 94.3 0.6 8.8e-27 93.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY49489.1 - 2.3e-10 40.2 13.2 2.3e-10 40.2 9.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLU PF13236.1 EPY49490.1 - 3.2e-76 255.6 0.0 6e-76 254.7 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EPY49490.1 - 5.9e-35 120.6 0.1 2.5e-34 118.6 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EPY49490.1 - 7.8e-17 60.9 8.5 5e-08 32.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat CLU_N PF15044.1 EPY49490.1 - 1.7e-16 60.1 0.5 4.5e-16 58.7 0.3 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EPY49490.1 - 1.9e-09 37.1 3.9 0.0027 17.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY49490.1 - 4.6e-05 22.8 1.5 0.91 9.2 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPY49490.1 - 0.00082 18.9 2.4 0.093 12.3 0.0 3.1 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 EPY49490.1 - 0.025 14.3 5.1 3.2 7.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TENA_THI-4 PF03070.11 EPY49491.1 - 3.7e-10 39.9 5.0 1.9e-06 27.7 0.0 2.1 1 1 1 2 2 2 2 TENA/THI-4/PQQC family Fungal_trans PF04082.13 EPY49492.1 - 1.3e-22 79.9 1.8 1.3e-22 79.9 1.2 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY49492.1 - 2.5e-10 40.0 14.6 4.6e-10 39.2 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CIMR PF00878.13 EPY49493.1 - 5.2e-12 45.7 0.1 2.8e-06 27.1 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EPY49493.1 - 6e-10 38.6 0.0 7.7e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EPY49493.1 - 0.11 11.7 1.3 0.72 9.0 0.4 2.3 2 1 0 2 2 2 0 Autophagy-related protein 27 Mito_carr PF00153.22 EPY49494.1 - 1.7e-67 223.1 3.4 3e-23 81.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EPY49495.1 - 9.1e-23 80.4 2.1 1.7e-22 79.5 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Palm_thioest PF02089.10 EPY49496.1 - 1.4e-44 152.0 0.0 2.2e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PAP2 PF01569.16 EPY49496.1 - 1.8e-15 56.7 1.8 4.6e-15 55.4 1.3 1.7 1 0 0 1 1 1 1 PAP2 superfamily Cyclin_N PF00134.18 EPY49497.1 - 1.2e-16 60.4 1.8 8e-11 41.6 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPY49497.1 - 0.026 14.4 0.9 0.43 10.5 0.0 2.3 1 1 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.14 EPY49497.1 - 0.046 13.5 1.4 0.13 12.1 0.2 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Pkinase PF00069.20 EPY49498.1 - 6.4e-43 146.7 0.1 1.4e-23 83.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49498.1 - 2e-14 53.3 0.1 4.2e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EPY49498.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 EPY49499.1 - 1.9e-37 128.8 43.6 1.9e-37 128.8 30.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY49499.1 - 5.6e-12 44.9 11.5 5.6e-12 44.9 7.9 3.0 2 2 1 3 3 3 2 Sugar (and other) transporter DUF1689 PF07954.6 EPY49499.1 - 4.3 7.1 6.8 11 5.8 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF1689) MFS_1 PF07690.11 EPY49500.1 - 3e-29 101.8 28.4 3e-29 101.8 19.7 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.7 EPY49500.1 - 3.5 7.1 8.5 0.2 11.2 0.1 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC zf-RING_2 PF13639.1 EPY49501.1 - 3.2e-10 39.6 6.1 5.9e-10 38.8 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPY49501.1 - 6.1e-07 29.0 4.6 1e-06 28.3 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPY49501.1 - 1.6e-05 24.4 6.1 2.8e-05 23.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY49501.1 - 0.00018 21.4 6.6 0.00033 20.6 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY49501.1 - 0.00072 19.1 2.8 0.0013 18.3 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPY49501.1 - 0.0026 17.8 1.5 0.0055 16.7 1.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPY49501.1 - 0.19 11.5 0.9 0.38 10.6 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EPY49501.1 - 0.82 9.4 3.9 1.4 8.6 2.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EPY49501.1 - 1.9 8.5 5.3 4.8 7.2 3.7 1.7 1 0 0 1 1 1 0 RING-like domain HA2 PF04408.18 EPY49502.1 - 2.8e-16 59.4 0.0 2.8e-16 59.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPY49502.1 - 1.2e-15 57.1 0.3 3.3e-15 55.6 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY49502.1 - 5.9e-11 42.1 0.1 1.8e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EPY49502.1 - 1.3e-08 34.6 0.1 3.8e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EPY49502.1 - 0.00011 22.3 0.0 0.00055 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EPY49502.1 - 0.0021 16.9 0.0 0.0052 15.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EPY49502.1 - 0.2 11.4 0.0 0.49 10.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AA_permease_2 PF13520.1 EPY49503.1 - 6.9e-65 219.2 53.1 8.5e-65 218.9 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPY49503.1 - 5.8e-14 51.2 45.2 7.5e-14 50.9 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease GDI PF00996.13 EPY49504.1 - 3.5e-47 160.7 0.1 5.5e-47 160.0 0.1 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor ABC1 PF03109.11 EPY49505.1 - 6.3e-34 116.5 0.0 1.1e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family TPR_11 PF13414.1 EPY49506.1 - 6.7e-07 28.8 1.4 3.6e-05 23.3 0.2 2.9 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.23 EPY49506.1 - 0.0018 17.7 3.6 0.015 14.8 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPY49506.1 - 0.006 16.4 4.5 0.015 15.2 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPY49506.1 - 0.0091 15.7 1.2 0.18 11.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPY49506.1 - 0.013 15.2 4.3 0.15 11.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Prolamin_like PF05617.6 EPY49506.1 - 0.021 14.9 1.3 0.33 11.1 0.1 3.0 4 0 0 4 4 4 0 Prolamin-like TPR_16 PF13432.1 EPY49506.1 - 0.022 15.4 0.0 0.18 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY49506.1 - 0.18 12.5 0.5 2.6 8.9 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 EPY49507.1 - 4.3e-16 58.0 9.8 5.2e-07 29.3 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1510 PF07423.6 EPY49507.1 - 1.3 8.3 32.5 0.57 9.5 10.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 EPY49507.1 - 4.9 7.0 14.9 3.3 7.5 1.6 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain Bot1p PF12298.3 EPY49508.1 - 1.2e-30 106.6 0.2 2e-30 106.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein HTH_28 PF13518.1 EPY49508.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydro_lipase PF04083.11 EPY49509.1 - 5.9e-21 73.5 0.0 1.1e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EPY49509.1 - 1.4e-17 64.0 0.0 2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPY49509.1 - 1.4e-10 41.0 0.0 7.4e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY49509.1 - 1.5e-10 41.3 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPY49509.1 - 2e-07 30.6 0.1 2.9e-05 23.6 0.0 2.6 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EPY49509.1 - 1.5e-05 24.5 0.2 0.0085 15.5 0.1 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 EPY49509.1 - 0.0016 17.7 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 EPY49509.1 - 0.0026 17.4 0.1 0.035 13.7 0.1 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF2974 PF11187.3 EPY49509.1 - 0.053 12.8 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DNA_pol_phi PF04931.8 EPY49510.1 - 5.2e-208 692.5 22.8 7e-208 692.1 15.8 1.2 1 0 0 1 1 1 1 DNA polymerase phi SRR1 PF07985.7 EPY49511.1 - 1.3e-10 40.9 0.1 2.2e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 SRR1 Epimerase PF01370.16 EPY49512.1 - 0.00011 21.7 0.0 0.00027 20.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPY49512.1 - 0.0003 19.7 0.0 0.0028 16.6 0.0 2.4 3 0 0 3 3 3 1 Male sterility protein DUF1886 PF09171.5 EPY49512.1 - 0.0055 15.7 0.1 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1886) Semialdhyde_dh PF01118.19 EPY49512.1 - 0.012 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EPY49512.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EPY49512.1 - 0.063 11.9 0.0 0.096 11.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPY49512.1 - 0.17 11.8 0.0 0.56 10.1 0.0 1.8 1 1 1 2 2 2 0 short chain dehydrogenase RNA_pol_Rpb8 PF03870.10 EPY49513.1 - 2e-41 141.3 2.2 1.8e-40 138.2 1.5 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb8 Ribosomal_L28 PF00830.14 EPY49514.1 - 1.3e-17 63.3 0.2 2.3e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family UPF0029 PF01205.14 EPY49515.1 - 4.1e-16 58.6 0.0 1.1e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Rootletin PF15035.1 EPY49515.1 - 0.011 15.6 4.7 0.019 14.9 3.3 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Muted PF14942.1 EPY49515.1 - 0.029 14.2 1.5 0.029 14.2 1.1 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein P16-Arc PF04699.9 EPY49515.1 - 0.068 13.1 1.1 0.1 12.6 0.7 1.4 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Viral_env_E26 PF11050.3 EPY49515.1 - 0.19 10.9 3.1 0.27 10.3 2.1 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 SMAP PF15477.1 EPY49516.1 - 6e-11 42.4 4.1 6e-11 42.4 2.9 3.1 2 1 0 2 2 2 1 Small acidic protein family ABC_tran PF00005.22 EPY49516.1 - 0.055 13.7 1.9 0.083 13.1 1.3 1.3 1 0 0 1 1 1 0 ABC transporter DUF1043 PF06295.7 EPY49516.1 - 0.081 12.5 5.0 0.14 11.8 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) BTV_NS2 PF04514.7 EPY49516.1 - 0.28 10.0 10.2 0.32 9.8 7.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1299 PF06975.6 EPY49516.1 - 0.8 9.6 6.5 2.5 8.0 4.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) TMPIT PF07851.8 EPY49516.1 - 2.5 7.0 5.2 3 6.8 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein NARP1 PF12569.3 EPY49516.1 - 2.8 6.6 14.4 3.5 6.2 10.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 EPY49516.1 - 9.3 4.1 14.6 11 3.8 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 EPY49517.1 - 7.4e-14 52.0 0.0 1.2e-12 48.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPY49517.1 - 1.5e-12 47.8 0.0 1.4e-11 44.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY49517.1 - 1.2e-10 41.6 0.0 3.1e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 EPY49517.1 - 1.5e-09 37.4 0.2 6.9e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 CDC6, C terminal NACHT PF05729.7 EPY49517.1 - 1.8e-05 24.4 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EPY49517.1 - 0.00021 20.2 0.0 0.00038 19.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 EPY49517.1 - 0.00033 19.7 0.0 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EPY49517.1 - 0.0036 17.0 0.1 0.073 12.7 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase Sigma54_activat PF00158.21 EPY49517.1 - 0.0057 16.1 0.0 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.9 EPY49517.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPY49517.1 - 0.011 15.4 0.1 0.038 13.7 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EPY49517.1 - 0.017 15.0 0.1 0.06 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EPY49517.1 - 0.019 13.8 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EPY49517.1 - 0.026 14.6 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EPY49517.1 - 0.048 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EPY49517.1 - 0.049 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.14 EPY49517.1 - 0.052 12.9 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GvpD PF07088.6 EPY49517.1 - 0.066 11.5 0.0 0.095 10.9 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein UvrD-helicase PF00580.16 EPY49517.1 - 0.067 12.4 0.3 0.71 9.1 0.1 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 EPY49517.1 - 0.22 11.0 3.0 3.3 7.2 2.1 2.4 1 1 0 1 1 1 0 AAA domain Pol_alpha_B_N PF08418.5 EPY49517.1 - 0.27 10.7 5.9 0.66 9.4 4.1 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal WD40 PF00400.27 EPY49518.1 - 6.1e-19 67.1 9.6 9.6e-08 31.6 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat DPPIV_N PF00930.16 EPY49518.1 - 0.012 14.1 1.3 3.4 6.1 0.3 3.3 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Rax2 PF12768.2 EPY49518.1 - 0.022 13.9 0.2 0.084 12.0 0.0 2.0 3 0 0 3 3 3 0 Cortical protein marker for cell polarity Glyco_hydro_15 PF00723.16 EPY49519.1 - 1.6e-73 247.8 0.0 1.8e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Reovirus_M2 PF05993.7 EPY49519.1 - 0.17 9.6 0.0 0.24 9.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) ALS_ss_C PF10369.4 EPY49520.1 - 4.5e-20 71.1 0.0 1.3e-18 66.5 0.0 2.5 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EPY49520.1 - 1.6e-12 46.5 0.3 3.1e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EPY49520.1 - 2.7e-10 39.9 0.1 5.8e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain Peptidase_M24 PF00557.19 EPY49521.1 - 1.2e-42 145.9 0.1 1.6e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.9 EPY49521.1 - 6.2 4.7 12.1 8.5 4.2 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim44 PF04280.10 EPY49522.1 - 1.1e-31 109.8 0.0 2e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain Enolase_C PF00113.17 EPY49524.1 - 8.2e-146 484.5 0.0 1.1e-145 484.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EPY49524.1 - 4.4e-56 188.4 0.0 7e-56 187.7 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EPY49524.1 - 0.019 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like HAD PF12710.2 EPY49526.1 - 1.3e-10 41.7 0.0 1.7e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPY49526.1 - 0.00099 18.3 0.0 0.86 8.7 0.1 2.2 1 1 1 2 2 2 2 Putative Phosphatase CPSase_L_D2 PF02786.12 EPY49527.1 - 8.1e-79 263.7 0.0 1.3e-78 263.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EPY49527.1 - 3.4e-60 202.8 0.0 6e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EPY49527.1 - 1.5e-34 118.3 0.1 3.1e-34 117.3 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPY49527.1 - 6.7e-28 96.7 0.0 2.2e-27 95.1 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EPY49527.1 - 1.1e-22 80.8 0.0 1.9e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EPY49527.1 - 6.5e-19 68.3 0.1 1.2e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EPY49527.1 - 1.1e-17 63.4 2.5 2.5e-17 62.2 1.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EPY49527.1 - 4.2e-16 58.6 0.0 2.3e-15 56.1 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EPY49527.1 - 3.1e-15 55.5 0.9 6.5e-09 35.3 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EPY49527.1 - 4.7e-10 39.1 0.0 8.5e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPY49527.1 - 8.4e-08 31.7 0.0 1.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EPY49527.1 - 9.2e-06 25.0 0.1 0.00089 18.4 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD PF00529.15 EPY49527.1 - 1.5e-05 24.4 0.4 0.0062 15.8 0.0 2.9 3 0 0 3 3 3 1 HlyD family secretion protein ATP-grasp_3 PF02655.9 EPY49527.1 - 4e-05 23.5 0.0 9.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EPY49527.1 - 0.00015 21.3 0.0 0.00073 19.0 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.1 EPY49527.1 - 0.00071 19.2 0.9 0.0028 17.3 0.6 2.0 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 EPY49527.1 - 0.0019 18.5 0.2 2 8.8 0.0 2.8 1 1 1 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.4 EPY49527.1 - 0.017 14.7 0.2 0.08 12.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.6 EPY49527.1 - 0.081 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 EPY49527.1 - 0.13 11.8 0.7 0.41 10.3 0.2 2.1 2 0 0 2 2 1 0 Glycine cleavage H-protein Ribosomal_L5_C PF00673.16 EPY49528.1 - 3.1e-23 81.3 0.0 4.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPY49528.1 - 4e-20 71.3 0.1 1e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 GTP_EFTU PF00009.22 EPY49529.1 - 1.3e-40 138.8 0.1 2.1e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EPY49529.1 - 2.2e-36 123.7 0.4 5e-36 122.6 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EPY49529.1 - 1.2e-13 51.0 0.6 2.6e-13 49.8 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPY49529.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPY49529.1 - 0.058 13.2 0.3 0.32 10.8 0.2 2.4 1 1 0 1 1 1 0 Dynamin family YdjO PF14169.1 EPY49529.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Pro_isomerase PF00160.16 EPY49530.1 - 3.1e-31 108.6 0.0 5.2e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EPY49530.1 - 2.8e-17 62.0 0.2 4.8e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49530.1 - 4.3e-13 49.0 0.1 7.9e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49530.1 - 2.4e-11 43.2 0.2 5.2e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_8 PF13523.1 EPY49531.1 - 2.5e-46 157.3 1.7 3.5e-46 156.8 1.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPY49531.1 - 0.017 15.3 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ArfGap PF01412.13 EPY49532.1 - 1.6e-32 111.7 0.6 1.6e-32 111.7 0.4 2.6 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf PH PF00169.24 EPY49532.1 - 1.4e-13 50.8 0.5 6e-13 48.8 0.1 2.2 2 0 0 2 2 2 1 PH domain Ribosomal_S24e PF01282.14 EPY49533.1 - 4e-34 116.2 0.0 6.1e-34 115.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e SLAC1 PF03595.12 EPY49534.1 - 3.7e-56 190.1 42.8 6.3e-52 176.2 26.8 2.0 2 0 0 2 2 2 2 Voltage-dependent anion channel Nucleopor_Nup85 PF07575.8 EPY49535.1 - 3.1e-118 395.4 8.3 3.6e-118 395.2 5.7 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin tRNA-synt_2 PF00152.15 EPY49536.1 - 5e-89 298.3 0.0 7.4e-89 297.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPY49536.1 - 1.5e-10 40.7 0.0 2.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPY49536.1 - 1.2e-06 27.8 0.0 0.0091 15.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPY49536.1 - 0.025 14.1 0.1 8.2 5.9 0.0 2.6 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) CDC73 PF05179.9 EPY49537.1 - 9.1e-89 297.4 0.2 1.1e-88 297.1 0.1 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family LRRNT_2 PF08263.7 EPY49537.1 - 0.0045 16.9 0.7 0.67 9.9 0.1 2.7 3 0 0 3 3 3 2 Leucine rich repeat N-terminal domain HA2 PF04408.18 EPY49538.1 - 1.4e-26 92.4 0.0 6e-26 90.4 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPY49538.1 - 1.8e-22 79.3 0.0 4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPY49538.1 - 4.2e-14 52.1 0.0 9.8e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY49538.1 - 4.7e-08 32.7 0.1 1.9e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPY49538.1 - 2.8e-05 24.2 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EPY49538.1 - 9.1e-05 22.3 0.4 0.24 11.1 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SRP54 PF00448.17 EPY49538.1 - 0.0015 17.9 0.1 0.0046 16.4 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EPY49538.1 - 0.0016 17.3 1.1 0.0056 15.6 0.8 2.0 1 1 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EPY49538.1 - 0.003 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.4 EPY49538.1 - 0.0034 16.4 0.6 0.0062 15.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.9 EPY49538.1 - 0.0054 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain NB-ARC PF00931.17 EPY49538.1 - 0.044 12.6 0.2 0.076 11.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EPY49538.1 - 0.047 13.9 1.8 0.14 12.4 0.1 2.5 2 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EPY49538.1 - 0.071 13.0 0.2 0.52 10.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EPY49539.1 - 9.6e-33 110.8 15.6 1.2e-09 37.6 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat RNA_pol_3_Rpc31 PF11705.3 EPY49539.1 - 0.11 12.4 27.9 0.099 12.5 2.6 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CRT10 PF08728.5 EPY49539.1 - 0.49 8.3 5.2 1 7.2 0.0 2.4 2 0 0 2 2 2 0 CRT10 Hid1 PF12722.2 EPY49539.1 - 3.2 5.2 9.4 5.3 4.5 6.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Phage_int_SAM_2 PF12834.2 EPY49540.1 - 0.0096 16.2 3.8 0.0096 16.2 2.6 2.3 2 1 0 2 2 2 1 Phage integrase, N-terminal Myosin_tail_1 PF01576.14 EPY49540.1 - 0.021 12.5 15.9 0.028 12.1 11.0 1.2 1 0 0 1 1 1 0 Myosin tail NAS PF03059.11 EPY49540.1 - 0.022 13.8 1.1 0.029 13.5 0.8 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein Integrase_DNA PF02920.10 EPY49540.1 - 0.034 13.5 2.2 0.047 13.1 0.6 1.8 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase zf-C4H2 PF10146.4 EPY49540.1 - 0.085 12.8 13.0 0.15 12.0 8.5 1.7 1 1 1 2 2 2 0 Zinc finger-containing protein Dna2 PF08696.6 EPY49540.1 - 0.3 10.3 10.9 0.14 11.4 3.7 2.1 1 1 1 2 2 2 0 DNA replication factor Dna2 Raptor_N PF14538.1 EPY49540.1 - 1.2 8.9 9.3 0.11 12.3 2.0 2.0 1 1 1 2 2 2 0 Raptor N-terminal CASPase like domain DUF1664 PF07889.7 EPY49540.1 - 1.5 8.6 9.7 0.86 9.4 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rabaptin PF03528.10 EPY49540.1 - 2.5 8.0 15.8 1.1 9.1 8.4 2.0 1 1 1 2 2 2 0 Rabaptin DUF4473 PF14747.1 EPY49540.1 - 4.3 7.6 12.6 5.7 7.2 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4473) DUF2400 PF09674.5 EPY49540.1 - 4.4 6.9 11.7 7.8 6.1 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) Rox3 PF08633.5 EPY49540.1 - 5.9 7.1 15.7 4 7.6 0.8 2.1 1 1 1 2 2 2 0 Rox3 mediator complex subunit TEX13 PF15186.1 EPY49540.1 - 6.4 6.3 11.5 0.43 10.1 1.4 2.2 1 1 0 2 2 2 0 Testis-expressed sequence 13 protein family Histidinol_dh PF00815.15 EPY49541.1 - 4.4e-163 542.7 0.7 5.2e-163 542.4 0.5 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Peptidase_S9 PF00326.16 EPY49542.1 - 7.1e-55 185.5 0.1 1.1e-54 184.9 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPY49542.1 - 3.4e-08 33.3 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPY49542.1 - 5e-07 28.5 0.1 9e-05 21.1 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PX PF00787.19 EPY49543.1 - 3.2e-21 75.2 0.8 3.2e-21 75.2 0.6 2.4 2 1 1 3 3 3 1 PX domain CCDC-167 PF15188.1 EPY49543.1 - 0.015 15.2 1.2 0.07 13.0 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF842 PF05811.8 EPY49543.1 - 2.4 7.6 8.6 6.3 6.2 0.1 3.5 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF842) GST_N PF02798.15 EPY49544.1 - 1.6e-15 56.9 0.0 3.6e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPY49544.1 - 1.3e-14 53.9 0.0 2.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPY49544.1 - 5.2e-13 49.0 0.0 8.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPY49544.1 - 1.9e-12 46.9 0.1 4.4e-12 45.8 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPY49544.1 - 5e-06 26.3 0.0 1.6e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY49544.1 - 0.0024 18.3 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NPL4 PF05021.10 EPY49545.1 - 2.7e-101 338.7 0.0 3.6e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EPY49545.1 - 4.9e-68 227.4 0.1 9.1e-68 226.5 0.1 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EPY49545.1 - 2.8e-08 33.9 0.0 9.4e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 SNARE_assoc PF09335.6 EPY49546.1 - 3.6e-08 33.6 2.9 3.6e-08 33.6 2.0 2.3 1 1 1 2 2 2 1 SNARE associated Golgi protein YtpI PF14007.1 EPY49546.1 - 0.071 13.0 3.4 5.1 7.1 0.1 2.6 2 1 0 2 2 2 0 YtpI-like protein Aha1_N PF09229.6 EPY49547.1 - 4e-30 104.4 0.1 5.5e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal WD40 PF00400.27 EPY49548.1 - 3.5e-20 71.0 4.7 7.3e-08 32.0 0.4 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPY49548.1 - 3.3e-16 58.9 0.0 8.3e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EPY49548.1 - 0.00086 19.0 0.3 0.0043 16.7 0.2 2.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1772 PF08592.6 EPY49549.1 - 3.4e-18 65.7 0.6 4.1e-18 65.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PHO4 PF01384.15 EPY49549.1 - 0.12 11.0 2.3 0.054 12.1 0.2 1.5 2 0 0 2 2 2 0 Phosphate transporter family LSM14 PF12701.2 EPY49550.1 - 9.4e-35 118.3 0.0 1.9e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EPY49550.1 - 1.3e-10 41.7 8.6 1.7e-07 31.7 0.3 2.5 1 1 1 2 2 2 2 FDF domain SM-ATX PF14438.1 EPY49550.1 - 6e-05 22.8 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 EPY49550.1 - 0.38 9.2 5.0 0.5 8.8 3.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gcd10p PF04189.8 EPY49551.1 - 2.6e-77 259.9 1.3 1.4e-75 254.2 0.3 2.8 2 1 0 2 2 2 2 Gcd10p family IL2 PF00715.12 EPY49551.1 - 0.11 12.2 0.2 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Interleukin 2 EF_TS PF00889.14 EPY49552.1 - 9.2e-22 77.4 0.8 2.2e-21 76.2 0.0 2.0 2 1 0 2 2 2 1 Elongation factor TS Brix PF04427.13 EPY49553.1 - 5e-40 137.2 0.5 7.8e-40 136.5 0.3 1.3 1 0 0 1 1 1 1 Brix domain Tubulin PF00091.20 EPY49554.1 - 8.1e-70 234.9 0.0 1.1e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPY49554.1 - 2.7e-49 166.4 0.0 4.6e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPY49554.1 - 0.0006 19.3 0.0 0.0016 17.9 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L37ae PF01780.14 EPY49555.1 - 6.4e-38 128.5 7.6 7.1e-38 128.3 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EPY49555.1 - 0.033 13.9 3.8 0.053 13.3 2.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EPY49555.1 - 0.035 13.5 1.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EPY49555.1 - 0.11 12.8 0.9 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EPY49555.1 - 0.18 11.7 0.1 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.10 EPY49555.1 - 0.26 10.8 0.2 0.26 10.8 0.2 2.0 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Lar_restr_allev PF14354.1 EPY49555.1 - 0.31 11.3 4.3 0.77 10.1 3.0 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-C2H2 PF00096.21 EPY49555.1 - 0.5 10.8 3.7 0.73 10.3 0.3 2.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type ATG_C PF09333.6 EPY49556.1 - 8.8e-26 89.9 0.0 1.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 ATG C terminal domain ATG2_CAD PF13329.1 EPY49556.1 - 2.1e-16 59.8 4.2 4.7e-16 58.7 1.1 2.9 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.2 EPY49556.1 - 1.1e-08 34.6 1.5 5.9e-08 32.2 1.0 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter E1-E2_ATPase PF00122.15 EPY49557.1 - 9.4e-78 260.3 0.3 2.2e-77 259.1 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPY49557.1 - 5.4e-46 156.4 4.3 5.4e-46 156.4 3.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPY49557.1 - 1e-29 104.5 0.2 4.9e-29 102.2 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY49557.1 - 3.5e-17 62.1 0.0 6.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPY49557.1 - 7.8e-16 57.2 0.0 2.2e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPY49557.1 - 1.1e-14 55.0 0.0 5.5e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPY49557.1 - 9.8e-07 28.6 1.7 6e-05 22.7 0.8 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ubiquitin PF00240.18 EPY49558.1 - 6.1e-06 25.5 0.1 2.6e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EPY49558.1 - 5e-05 23.4 0.0 0.00024 21.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EPY49558.1 - 0.044 13.4 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SNARE PF05739.14 EPY49559.1 - 2.2e-16 59.2 3.9 6.4e-16 57.7 1.3 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EPY49559.1 - 1.1e-11 44.6 2.5 1.1e-11 44.6 1.8 2.8 2 1 0 2 2 2 1 Syntaxin-like protein ABC2_membrane_3 PF12698.2 EPY49559.1 - 0.0043 16.1 1.4 0.0058 15.7 1.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein DASH_Dad2 PF08654.5 EPY49559.1 - 0.09 12.7 7.3 0.28 11.1 0.0 3.0 2 1 1 3 3 3 0 DASH complex subunit Dad2 Dispanin PF04505.7 EPY49559.1 - 0.14 11.7 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF1664 PF07889.7 EPY49559.1 - 0.16 11.7 8.1 2.9 7.6 0.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF930 PF06059.7 EPY49559.1 - 0.18 12.0 2.1 14 5.9 0.9 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF930) Acyl-CoA_dh_2 PF08028.6 EPY49559.1 - 0.24 11.6 4.6 0.67 10.2 3.2 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Lipoprotein_7 PF01540.11 EPY49559.1 - 0.3 10.1 7.0 2.7 6.9 0.3 2.3 1 1 0 2 2 2 0 Adhesin lipoprotein TMPIT PF07851.8 EPY49559.1 - 1.3 7.9 8.8 1.6 7.6 2.4 2.2 1 1 1 2 2 2 0 TMPIT-like protein TraH PF06122.6 EPY49559.1 - 1.7 7.3 11.1 0.29 9.8 3.1 2.4 2 1 1 3 3 3 0 Conjugative relaxosome accessory transposon protein DUF912 PF06024.7 EPY49559.1 - 3.1 7.8 6.8 0.33 11.0 0.2 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GLE1 PF07817.8 EPY49560.1 - 1.6e-69 233.7 0.0 1.6e-69 233.7 0.0 1.8 2 1 0 2 2 2 1 GLE1-like protein Borrelia_P83 PF05262.6 EPY49560.1 - 0.22 9.7 19.6 0.27 9.4 13.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein MAP7 PF05672.6 EPY49560.1 - 0.34 10.2 45.6 0.58 9.5 31.6 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family CAF-1_p150 PF11600.3 EPY49560.1 - 0.52 9.6 43.9 1.4 8.2 30.3 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 EPY49560.1 - 1.2 7.6 6.2 1.6 7.2 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF663 PF04950.7 EPY49561.1 - 4e-93 311.6 0.1 4e-93 311.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPY49561.1 - 4.1e-29 99.9 0.0 1.3e-28 98.3 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EPY49561.1 - 7.3e-08 32.0 0.0 1.5e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EPY49561.1 - 4.5e-05 23.5 0.0 0.00019 21.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EPY49561.1 - 0.00017 21.6 0.0 0.0005 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EPY49561.1 - 0.00033 20.5 0.3 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPY49561.1 - 0.00034 20.5 0.1 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EPY49561.1 - 0.00056 20.1 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPY49561.1 - 0.0006 20.6 0.0 0.0006 20.6 0.0 3.4 2 1 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 EPY49561.1 - 0.0013 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EPY49561.1 - 0.0016 18.9 0.2 0.0064 16.9 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein MobB PF03205.9 EPY49561.1 - 0.0017 18.0 0.1 0.011 15.4 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EPY49561.1 - 0.0017 18.3 0.9 0.024 14.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPY49561.1 - 0.002 17.8 0.1 0.0073 16.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EPY49561.1 - 0.003 17.8 0.0 0.003 17.8 0.0 3.1 3 1 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EPY49561.1 - 0.015 14.7 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EPY49561.1 - 0.027 13.8 0.0 0.075 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPY49561.1 - 0.033 14.5 0.0 0.033 14.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EPY49561.1 - 0.038 14.1 0.5 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 EPY49561.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EPY49561.1 - 0.093 11.4 0.0 0.31 9.7 0.0 1.8 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 EPY49561.1 - 0.095 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPY49561.1 - 0.12 12.1 2.7 2.1 8.1 0.0 3.5 2 1 0 3 3 3 0 Dynamin family Viral_helicase1 PF01443.13 EPY49561.1 - 0.14 11.6 0.1 0.36 10.3 0.1 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EPY49561.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Adeno_IVa2 PF02456.10 EPY49561.1 - 0.16 10.5 0.0 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein NTPase_1 PF03266.10 EPY49561.1 - 0.31 10.7 3.4 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 EPY49561.1 - 0.5 9.9 0.0 0.5 9.9 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.12 EPY49561.1 - 0.95 9.2 5.4 2.3 7.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Whi5 PF08528.6 EPY49562.1 - 8.7e-10 37.9 0.3 1.7e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 Whi5 like Hist_deacetyl PF00850.14 EPY49563.1 - 6.2e-92 308.2 0.0 1.1e-91 307.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EPY49563.1 - 1.5e-42 145.0 0.1 2.4e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain Trehalase PF01204.13 EPY49564.1 - 6.7e-186 618.8 2.0 7.9e-186 618.6 1.4 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EPY49564.1 - 3.4e-17 61.4 0.1 3.4e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Neutral trehalase Ca2+ binding domain Phasin PF05597.6 EPY49565.1 - 0.07 12.8 0.3 0.07 12.8 0.2 2.4 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Osmo_CC PF08946.5 EPY49565.1 - 0.19 11.7 4.3 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF536 PF04394.9 EPY49565.1 - 3.7 7.3 8.4 6.8 6.5 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function, DUF536 PhaC_N PF07167.8 EPY49566.1 - 0.068 12.5 0.1 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus GTP_EFTU PF00009.22 EPY49567.1 - 1.6e-57 194.0 0.0 2.5e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EPY49567.1 - 2.5e-22 78.5 0.0 5.3e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EPY49567.1 - 6.3e-13 48.3 0.3 3.5e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPY49567.1 - 9.2e-10 38.4 0.2 1.8e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPY49567.1 - 0.00079 19.3 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EPY49567.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EPY49567.1 - 0.033 14.6 0.0 0.14 12.6 0.0 2.2 1 0 0 1 1 1 0 Miro-like protein RRM_1 PF00076.17 EPY49568.1 - 1.5e-30 104.5 0.1 6.4e-16 57.7 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49568.1 - 1.9e-21 75.7 0.0 4.3e-11 42.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49568.1 - 2.5e-12 46.4 0.0 4.6e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4264 PF14084.1 EPY49568.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Aminotran_5 PF00266.14 EPY49569.1 - 1e-22 80.4 0.0 1.3e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPY49569.1 - 0.00093 17.5 0.0 0.0013 17.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPY49569.1 - 0.0024 16.8 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 EPY49569.1 - 0.011 14.2 0.0 0.02 13.3 0.0 1.5 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pyridoxal_deC PF00282.14 EPY49569.1 - 0.15 10.4 0.0 0.26 9.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Rep_fac-A_C PF08646.5 EPY49570.1 - 1.7e-51 173.7 5.4 1.1e-49 167.9 1.9 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EPY49570.1 - 4.1e-30 103.5 0.2 8.5e-30 102.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EPY49570.1 - 2.5e-17 62.4 1.0 6.6e-14 51.5 0.0 3.5 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 EPY49570.1 - 0.00013 22.0 0.2 0.00051 20.0 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF223 IBR PF01485.16 EPY49570.1 - 0.64 9.9 5.1 0.19 11.5 0.5 2.1 2 0 0 2 2 2 0 IBR domain Pkinase PF00069.20 EPY49571.1 - 1.9e-49 168.1 0.0 2.8e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49571.1 - 5.2e-32 110.9 0.0 7.8e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49571.1 - 0.033 13.1 0.4 0.092 11.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EPY49571.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.17 EPY49572.1 - 5.7e-38 128.3 0.2 1.5e-17 63.0 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49572.1 - 1.3e-31 108.3 0.1 4.6e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49572.1 - 2.7e-12 46.3 0.0 8.6e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY49572.1 - 0.0077 15.9 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif 6PGD PF00393.14 EPY49573.1 - 1.4e-130 434.7 0.0 1.8e-130 434.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPY49573.1 - 5.8e-51 172.5 0.0 9e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase YfhO PF09586.5 EPY49574.1 - 0.28 9.1 11.4 0.38 8.7 7.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pirin PF02678.11 EPY49575.1 - 2.2e-14 53.2 0.9 1.2e-12 47.5 0.6 2.4 1 1 0 1 1 1 1 Pirin Peptidase_M20 PF01546.23 EPY49576.1 - 3.2e-28 98.5 0.0 5.1e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPY49576.1 - 2.3e-16 59.5 0.0 6e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain tRNA-synt_2 PF00152.15 EPY49577.1 - 1.4e-66 224.6 0.0 7.1e-66 222.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) Myb_DNA-binding PF00249.26 EPY49578.1 - 7.2e-23 80.3 8.0 1.1e-10 41.3 0.1 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY49578.1 - 2.5e-16 59.4 11.7 2.9e-12 46.4 1.0 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain TFIIF_beta PF02270.10 EPY49579.1 - 2e-80 270.5 0.2 2.7e-53 181.5 0.0 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit Sec23_trunk PF04811.10 EPY49580.1 - 4.8e-14 52.3 0.7 1.1e-13 51.1 0.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPY49580.1 - 4.8e-09 35.5 0.0 1.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPY49580.1 - 1e-06 29.1 0.3 3.1e-06 27.5 0.2 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPY49580.1 - 2.6e-06 26.8 4.1 8.5e-06 25.2 2.8 2.0 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec3_C_2 PF15278.1 EPY49580.1 - 0.011 15.8 0.1 0.011 15.8 0.1 2.6 4 0 0 4 4 4 0 Sec3 exocyst complex subunit WD40 PF00400.27 EPY49581.1 - 1.8e-24 84.6 11.3 9.6e-07 28.4 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPY49581.1 - 6.2e-07 29.3 0.1 0.0059 16.3 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Glyco_hydro_76 PF03663.9 EPY49582.1 - 1.3e-122 409.8 27.4 1.6e-122 409.5 19.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 VKOR PF07884.9 EPY49582.1 - 0.086 12.6 2.4 7.8 6.3 0.1 2.7 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Glyco_hydro_76 PF03663.9 EPY49583.1 - 2.8e-113 379.0 19.3 3.6e-113 378.6 13.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Guanylate_kin PF00625.16 EPY49584.1 - 3.2e-59 199.4 0.0 3.8e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_17 PF13207.1 EPY49584.1 - 7.6e-06 26.7 0.1 1.4e-05 25.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY49584.1 - 3.4e-05 24.1 0.3 0.00015 22.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY49584.1 - 3.7e-05 23.7 0.1 8.4e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EPY49584.1 - 3.9e-05 23.4 0.6 0.00023 20.9 0.4 2.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EPY49584.1 - 4.3e-05 23.6 0.2 0.00038 20.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPY49584.1 - 4.3e-05 23.4 0.3 0.00076 19.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPY49584.1 - 0.00013 21.1 0.0 0.00029 20.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPY49584.1 - 0.00064 19.6 0.0 0.00082 19.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EPY49584.1 - 0.0011 19.3 0.0 0.0015 18.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 EPY49584.1 - 0.0014 19.1 0.0 0.0028 18.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EPY49584.1 - 0.0017 17.9 0.1 0.0052 16.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 EPY49584.1 - 0.0038 16.7 0.3 0.0038 16.7 0.2 1.4 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 EPY49584.1 - 0.0047 17.0 0.0 0.0078 16.3 0.0 1.6 1 1 0 1 1 1 1 RNA helicase PTS_IIB PF02302.12 EPY49584.1 - 0.0074 16.7 0.0 8 7.0 0.0 2.9 2 1 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA_29 PF13555.1 EPY49584.1 - 0.0089 15.5 0.1 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EPY49584.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EPY49584.1 - 0.011 15.4 0.2 0.048 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EPY49584.1 - 0.013 15.1 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 EPY49584.1 - 0.016 15.0 0.0 0.035 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EPY49584.1 - 0.022 14.4 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EPY49584.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPY49584.1 - 0.032 14.5 0.7 0.081 13.2 0.5 1.7 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EPY49584.1 - 0.052 13.3 1.2 0.9 9.3 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EPY49584.1 - 0.07 12.9 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.1 EPY49584.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EPY49584.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Fungal_trans PF04082.13 EPY49585.1 - 2.7e-33 114.9 7.9 2.7e-33 114.9 5.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EPY49585.1 - 5.7e-08 32.5 13.0 2.3e-05 24.4 2.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPY49585.1 - 6e-08 32.5 13.8 8.8e-05 22.6 3.0 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPY49585.1 - 5.7e-05 23.1 8.5 0.00015 21.8 2.1 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-Di19 PF05605.7 EPY49585.1 - 0.0028 17.7 0.3 0.011 15.8 0.2 2.0 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EPY49585.1 - 4.3 7.5 6.7 27 5.0 0.7 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4646 PF15496.1 EPY49586.1 - 1.6e-34 118.5 0.2 4.6e-34 117.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 EPY49586.1 - 1.5e-05 24.8 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF624 PF04854.9 EPY49586.1 - 0.1 12.4 0.5 0.82 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 ADH_N PF08240.7 EPY49587.1 - 3.5e-24 84.6 2.2 3.5e-24 84.6 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPY49587.1 - 1.1e-11 44.3 0.0 2.9e-09 36.5 0.0 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EPY49587.1 - 3.4e-06 26.5 2.9 6.4e-06 25.7 0.0 2.8 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 EPY49587.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_3 PF00202.16 EPY49588.1 - 4e-91 305.3 0.0 4.7e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPY49588.1 - 0.00027 19.9 0.0 0.00057 18.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II AAA_26 PF13500.1 EPY49589.1 - 1.2e-54 185.0 0.1 1.4e-54 184.7 0.1 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EPY49589.1 - 0.0018 17.7 1.3 0.0088 15.4 0.9 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain VIT1 PF01988.14 EPY49590.1 - 2.7e-56 190.4 10.9 3.1e-56 190.2 7.6 1.0 1 0 0 1 1 1 1 VIT family Claudin_2 PF13903.1 EPY49590.1 - 1.9 8.1 7.4 1.7 8.2 0.4 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction FAD_binding_8 PF08022.7 EPY49591.1 - 9.4e-30 102.5 0.2 5.5e-29 100.1 0.0 2.4 3 0 0 3 3 3 1 FAD-binding domain NAD_binding_6 PF08030.7 EPY49591.1 - 2.2e-15 56.9 0.0 1.4e-14 54.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPY49591.1 - 2.4e-12 47.0 10.9 2.4e-12 47.0 7.5 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPY49591.1 - 0.022 15.3 0.0 0.066 13.7 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF21 PF01595.15 EPY49591.1 - 0.072 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF21 Hydrolase_3 PF08282.7 EPY49592.1 - 1.5e-52 178.7 0.0 1.7e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EPY49592.1 - 3.9e-11 42.7 0.0 1.8e-05 24.2 0.0 2.3 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_6 PF13344.1 EPY49592.1 - 0.064 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY49592.1 - 0.14 12.5 0.0 2.3 8.5 0.0 2.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.1 EPY49593.1 - 1e-17 64.3 0.1 1.3e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY49593.1 - 9.7e-15 54.4 0.1 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY49593.1 - 2.3e-12 47.2 0.0 6.5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY49593.1 - 2.4e-12 47.1 0.0 4.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY49593.1 - 1.5e-08 35.1 0.0 2.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY49593.1 - 8.3e-08 32.5 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY49593.1 - 4.6e-06 26.1 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPY49593.1 - 4.8e-06 26.5 0.0 9.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPY49593.1 - 7.2e-05 22.0 0.0 0.00023 20.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EPY49593.1 - 0.0028 16.5 0.0 0.0051 15.7 0.0 1.4 1 1 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EPY49593.1 - 0.0041 16.1 0.0 0.0067 15.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EPY49593.1 - 0.0044 16.6 0.0 0.063 12.9 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain NodS PF05401.6 EPY49593.1 - 0.052 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) FmrO PF07091.6 EPY49593.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 EPY49593.1 - 0.095 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) HMG_box PF00505.14 EPY49594.1 - 0.0021 18.2 0.7 0.021 15.0 0.0 2.6 1 1 1 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPY49594.1 - 0.018 15.3 0.7 0.05 13.9 0.5 1.8 1 1 0 1 1 1 0 HMG-box domain Homeobox_KN PF05920.6 EPY49595.1 - 8.9e-14 50.9 0.7 1.7e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPY49595.1 - 1.9e-06 27.3 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EPY49595.1 - 0.0096 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF4496 PF14908.1 EPY49596.1 - 0.0043 16.9 0.5 0.0047 16.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) HMG_box PF00505.14 EPY49597.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Filament PF00038.16 EPY49598.1 - 0.0083 15.6 5.4 0.0083 15.6 3.7 1.8 1 1 1 2 2 2 2 Intermediate filament protein Rsa3 PF14615.1 EPY49598.1 - 0.039 13.2 0.5 0.091 12.0 0.4 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Atg14 PF10186.4 EPY49598.1 - 0.095 11.6 9.1 0.11 11.3 6.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 EPY49598.1 - 1.7 8.5 7.1 2.1 8.2 4.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TEX13 PF15186.1 EPY49598.1 - 2.3 7.7 7.9 0.46 10.0 2.1 2.0 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family IncA PF04156.9 EPY49598.1 - 2.8 7.4 10.9 4.1 6.9 7.5 1.3 1 0 0 1 1 1 0 IncA protein Ribosomal_60s PF00428.14 EPY49599.1 - 3.1e-25 88.3 10.5 3.5e-25 88.2 7.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SSF PF00474.12 EPY49600.1 - 2e-21 76.1 21.7 2e-21 76.1 15.1 1.8 2 1 0 2 2 2 1 Sodium:solute symporter family AAA PF00004.24 EPY49601.1 - 5.4e-44 149.5 0.0 9.9e-44 148.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPY49601.1 - 1.1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPY49601.1 - 2.1e-06 27.5 0.0 1.1e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPY49601.1 - 5.1e-06 26.6 0.1 0.0003 20.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY49601.1 - 5.9e-06 26.3 0.1 2.7e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPY49601.1 - 3.7e-05 24.5 0.0 8.8e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPY49601.1 - 0.00013 21.0 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPY49601.1 - 0.00035 20.2 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EPY49601.1 - 0.00064 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EPY49601.1 - 0.00089 18.0 0.1 0.002 16.8 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 EPY49601.1 - 0.001 18.9 0.0 0.0036 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPY49601.1 - 0.0011 18.4 0.7 0.18 11.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 EPY49601.1 - 0.0014 17.7 0.0 0.0034 16.5 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 EPY49601.1 - 0.0019 18.0 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY49601.1 - 0.0022 18.2 0.3 0.0099 16.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPY49601.1 - 0.0029 17.6 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPY49601.1 - 0.0037 16.8 0.0 0.0094 15.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EPY49601.1 - 0.0039 16.3 0.0 0.0088 15.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EPY49601.1 - 0.0087 15.2 0.0 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EPY49601.1 - 0.0088 15.2 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.17 EPY49601.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EPY49601.1 - 0.029 13.7 0.0 0.11 11.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EPY49601.1 - 0.03 13.8 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EPY49601.1 - 0.031 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPY49601.1 - 0.044 13.4 0.0 0.74 9.4 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EPY49601.1 - 0.051 12.4 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EPY49601.1 - 0.059 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2072 PF09845.4 EPY49601.1 - 0.082 12.8 0.6 0.19 11.6 0.4 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NB-ARC PF00931.17 EPY49601.1 - 0.098 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.1 EPY49601.1 - 0.12 10.8 0.2 2.5 6.4 0.3 2.1 2 0 0 2 2 2 0 AAA domain HhH-GPD PF00730.20 EPY49602.1 - 6.1e-18 65.0 0.0 9.2e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RhoGAP PF00620.22 EPY49604.1 - 1.5e-44 151.2 0.3 6.7e-44 149.1 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EPY49604.1 - 8.5e-09 35.4 1.0 8.5e-09 35.4 0.7 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain CMS1 PF14617.1 EPY49605.1 - 2.8e-74 249.3 8.1 3.4e-74 249.1 5.6 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EPY49605.1 - 9.7e-07 28.4 0.6 3.5e-06 26.6 0.3 1.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase TFIIF_alpha PF05793.7 EPY49605.1 - 0.61 8.3 14.9 0.79 8.0 10.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3490 PF11995.3 EPY49605.1 - 0.65 9.5 0.0 0.65 9.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3490) CTNNB1_binding PF08347.6 EPY49605.1 - 5.5 7.1 10.3 8.5 6.5 7.1 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding DUF2404 PF10296.4 EPY49606.1 - 1.9e-25 88.8 0.0 4.4e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) SUI1 PF01253.17 EPY49607.1 - 1.1e-29 101.9 1.2 1.5e-29 101.6 0.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Yqai PF09466.5 EPY49607.1 - 0.045 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein Yqai Ctr PF04145.10 EPY49609.1 - 2.6e-25 89.1 10.0 3.5e-24 85.4 6.9 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.15 EPY49609.1 - 0.043 13.2 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 ATPase_gene1 PF09527.5 EPY49609.1 - 0.086 12.6 5.7 0.76 9.6 0.1 2.4 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Abi PF02517.11 EPY49609.1 - 0.4 10.8 6.7 4.4 7.5 0.3 2.1 1 1 1 2 2 2 0 CAAX protease self-immunity IF3_C PF00707.17 EPY49610.1 - 2.3e-10 40.0 0.0 4.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EPY49610.1 - 0.00079 18.8 1.3 0.0013 18.0 0.9 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF3378 PF11858.3 EPY49610.1 - 0.036 14.1 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) Peptidase_M16_C PF05193.16 EPY49611.1 - 2.3e-37 128.4 0.0 3.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPY49611.1 - 5.1e-35 120.4 0.0 1.3e-34 119.0 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_5 PF07728.9 EPY49611.1 - 0.049 13.3 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YjeF_N PF03853.10 EPY49612.1 - 1.1e-24 86.9 0.0 1.9e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EPY49612.1 - 8.9e-11 42.2 8.4 8.9e-11 42.2 5.8 2.1 2 0 0 2 2 2 1 FDF domain ORC6 PF05460.8 EPY49612.1 - 0.004 16.3 13.7 0.013 14.6 8.9 1.9 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) SM-ATX PF14438.1 EPY49612.1 - 0.023 14.6 0.0 0.082 12.8 0.0 2.0 1 0 0 1 1 1 0 Ataxin 2 SM domain Complex1_51K PF01512.12 EPY49613.1 - 3.9e-30 104.5 0.0 6.3e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit SLBB PF10531.4 EPY49613.1 - 0.00032 20.5 0.0 0.00074 19.3 0.0 1.7 1 0 0 1 1 1 1 SLBB domain NADH_4Fe-4S PF10589.4 EPY49613.1 - 0.0011 18.0 0.0 0.0037 16.3 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Acetyltransf_3 PF13302.1 EPY49614.1 - 3.2e-19 69.4 0.0 3.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPY49614.1 - 4.2e-10 39.5 0.0 7.2e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPY49614.1 - 1.9e-05 24.5 0.0 9.7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPY49614.1 - 0.0007 19.5 0.1 0.0039 17.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3210 PF11489.3 EPY49615.1 - 7.3e-24 84.4 52.0 1.2e-14 54.0 10.3 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3210) Ribosomal_S21e PF01249.13 EPY49616.1 - 2.4e-40 136.3 0.1 2.7e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Elong_Iki1 PF10483.4 EPY49617.1 - 8.2e-65 218.9 0.0 9.8e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Ribosomal_L16 PF00252.13 EPY49618.1 - 1.2e-31 109.1 0.2 1.5e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CENP-K PF11802.3 EPY49619.1 - 1e-27 97.0 7.5 1.3e-27 96.7 5.2 1.1 1 0 0 1 1 1 1 Centromere-associated protein K DUF2315 PF10231.4 EPY49619.1 - 0.19 11.6 3.9 0.41 10.5 2.6 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) Lzipper-MIP1 PF14389.1 EPY49619.1 - 0.34 11.0 11.3 4.2 7.5 3.1 3.4 3 1 1 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DnaI_N PF07319.6 EPY49619.1 - 1.4 9.2 9.3 0.39 11.0 1.6 3.2 2 1 1 4 4 4 0 Primosomal protein DnaI N-terminus DUF4164 PF13747.1 EPY49619.1 - 6.1 7.0 9.2 0.92 9.6 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF972 PF06156.8 EPY49619.1 - 7.1 7.0 11.5 5 7.5 4.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Aminotran_1_2 PF00155.16 EPY49620.1 - 1.3e-36 126.3 0.0 2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPY49620.1 - 0.00019 19.8 0.0 0.00029 19.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Lactonase PF10282.4 EPY49621.1 - 4.2e-68 229.9 0.0 4.6e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.16 EPY49621.1 - 0.026 14.4 0.7 1.9 8.5 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Arylesterase PF01731.15 EPY49621.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Cytochrom_C1 PF02167.10 EPY49622.1 - 2.5e-82 275.7 0.0 4e-82 275.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EPY49622.1 - 0.0022 18.1 0.0 0.0063 16.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EPY49622.1 - 0.11 13.3 0.6 1.2 10.0 0.4 2.5 1 1 0 1 1 1 0 Cytochrome c RhoGEF PF00621.15 EPY49623.1 - 1.2e-26 93.7 5.4 8.1e-26 90.9 0.6 2.3 2 0 0 2 2 2 2 RhoGEF domain BAR PF03114.13 EPY49623.1 - 0.031 13.7 0.3 0.28 10.6 0.0 2.5 2 0 0 2 2 2 0 BAR domain RRS1 PF04939.7 EPY49624.1 - 3.5e-55 185.9 5.2 3.9e-55 185.7 3.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) ig PF00047.20 EPY49624.1 - 0.051 13.7 0.3 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF3315 PF11776.3 EPY49624.1 - 0.48 9.9 2.1 0.44 10.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3315) DAP3 PF10236.4 EPY49625.1 - 3.1e-60 203.6 0.0 4.3e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Telomerase_RBD PF12009.3 EPY49626.1 - 2.1e-36 124.8 9.3 2.1e-36 124.8 6.4 3.1 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EPY49626.1 - 3.3e-11 42.9 4.8 6.5e-10 38.7 1.8 3.0 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PWWP PF00855.12 EPY49627.1 - 1.8e-18 66.4 0.3 1.8e-18 66.4 0.2 2.3 2 0 0 2 2 2 1 PWWP domain DUF4616 PF15394.1 EPY49627.1 - 0.00074 18.6 5.2 0.0063 15.5 0.3 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4616) DUF4537 PF15057.1 EPY49627.1 - 0.05 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Cut8_N PF14482.1 EPY49627.1 - 9.8 6.2 11.8 0.34 10.9 1.3 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Ribosomal_S4 PF00163.14 EPY49628.1 - 9.6e-30 102.8 1.3 1.5e-29 102.1 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPY49628.1 - 7.1e-11 41.3 1.0 7.1e-11 41.3 0.7 2.4 3 0 0 3 3 3 1 S4 domain Mito_carr PF00153.22 EPY49629.1 - 2.9e-41 139.0 0.2 2.3e-17 62.4 0.0 3.8 1 1 2 3 3 3 3 Mitochondrial carrier protein ATP_sub_h PF10775.4 EPY49630.1 - 2.7e-14 52.6 0.5 4.2e-14 52.0 0.4 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ABC_tran PF00005.22 EPY49631.1 - 3e-46 157.1 2.4 2.6e-22 79.6 0.0 3.1 4 0 0 4 4 2 2 ABC transporter ABC_tran_2 PF12848.2 EPY49631.1 - 2.3e-23 81.8 7.2 2.3e-23 81.8 5.0 2.4 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 EPY49631.1 - 1.8e-14 54.4 4.3 0.0088 16.0 0.0 5.1 3 2 1 5 5 5 3 AAA domain SMC_N PF02463.14 EPY49631.1 - 4.9e-10 39.0 0.4 0.18 11.0 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPY49631.1 - 3.9e-09 37.3 1.5 0.008 16.9 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPY49631.1 - 5.7e-08 32.1 0.2 0.013 14.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPY49631.1 - 2.5e-07 30.8 0.0 0.013 15.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPY49631.1 - 1.7e-06 28.1 0.6 0.079 12.9 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPY49631.1 - 2.9e-06 27.2 0.1 0.037 13.9 0.0 3.2 2 2 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EPY49631.1 - 5.1e-06 26.2 0.3 0.043 13.5 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EPY49631.1 - 2e-05 23.5 0.2 0.18 10.5 0.1 2.4 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EPY49631.1 - 2.1e-05 24.1 0.0 0.1 12.0 0.0 3.5 3 0 0 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EPY49631.1 - 2.9e-05 24.3 6.3 0.16 12.2 0.0 4.5 5 1 0 5 5 4 2 AAA domain AAA_30 PF13604.1 EPY49631.1 - 3.8e-05 23.3 0.0 0.021 14.3 0.0 3.5 3 1 0 3 3 3 1 AAA domain Miro PF08477.8 EPY49631.1 - 4e-05 24.1 0.0 0.47 10.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_14 PF13173.1 EPY49631.1 - 8.2e-05 22.5 0.0 1.1 9.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain NACHT PF05729.7 EPY49631.1 - 0.00013 21.6 0.0 0.42 10.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 EPY49631.1 - 0.00015 21.0 0.1 0.44 9.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EPY49631.1 - 0.00016 21.4 0.1 0.21 11.5 0.1 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EPY49631.1 - 0.00026 20.7 0.0 0.84 9.3 0.0 3.0 3 0 0 3 3 3 2 NTPase AAA_33 PF13671.1 EPY49631.1 - 0.00033 20.5 0.0 0.26 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPY49631.1 - 0.00036 20.5 0.7 0.18 11.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 EPY49631.1 - 0.00046 20.3 0.1 0.67 10.1 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPY49631.1 - 0.0007 19.7 0.0 0.41 10.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 EPY49631.1 - 0.001 18.8 4.5 0.72 9.6 0.0 4.0 3 1 1 4 4 3 2 Dynamin family AAA_25 PF13481.1 EPY49631.1 - 0.0051 16.2 0.6 3.3 7.0 0.1 2.9 2 2 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EPY49631.1 - 0.0086 15.0 0.0 0.45 9.4 0.0 2.8 3 0 0 3 3 3 1 KAP family P-loop domain T2SE PF00437.15 EPY49631.1 - 0.013 14.4 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EPY49631.1 - 0.014 14.8 0.4 2.3 7.6 0.1 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EPY49631.1 - 0.024 14.9 21.3 0.26 11.5 0.0 4.6 5 0 0 5 5 5 0 AAA domain ATP_bind_1 PF03029.12 EPY49631.1 - 0.033 13.7 0.0 0.64 9.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EPY49631.1 - 0.038 13.7 0.1 14 5.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EPY49631.1 - 0.045 13.5 0.0 0.045 13.5 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function DUF87 GBP_repeat PF02526.9 EPY49631.1 - 0.046 13.1 0.7 0.41 10.0 0.1 2.3 2 0 0 2 2 2 0 Glycophorin-binding protein ATP-synt_ab PF00006.20 EPY49631.1 - 0.089 12.2 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EPY49631.1 - 2.6 7.4 10.9 0.6 9.5 0.0 3.8 3 1 1 4 4 4 0 FtsK/SpoIIIE family AAA_15 PF13175.1 EPY49631.1 - 8.6 5.2 17.6 1 8.3 0.0 5.2 4 2 1 5 5 5 0 AAA ATPase domain Elongin_A PF06881.6 EPY49632.1 - 2e-25 89.2 1.8 3.1e-25 88.6 1.3 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A MUG2_C PF08593.5 EPY49632.1 - 7.7 6.8 7.5 20 5.5 0.2 3.0 3 0 0 3 3 3 0 Meiotically up-regulated glycoproteins C-terminal RRM_1 PF00076.17 EPY49633.1 - 2e-16 59.3 0.0 3.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49633.1 - 2.6e-11 43.3 0.0 4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49633.1 - 4.2e-10 39.3 0.0 7e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S51 PF03575.12 EPY49633.1 - 0.032 13.9 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 DUF3791 PF12668.2 EPY49633.1 - 0.076 12.6 0.1 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) WD40 PF00400.27 EPY49634.1 - 1.8e-17 62.4 1.6 9e-07 28.5 0.0 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat PQQ PF01011.16 EPY49634.1 - 0.013 14.9 0.0 1.3 8.7 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat zf-HIT PF04438.11 EPY49635.1 - 2.2e-08 33.6 8.3 5.2e-08 32.3 5.7 1.7 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EPY49635.1 - 0.1 12.5 11.8 0.2 11.5 8.2 1.6 1 0 0 1 1 1 0 MYND finger PolC_DP2 PF03833.8 EPY49635.1 - 0.45 8.1 3.9 0.53 7.8 2.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-B_box PF00643.19 EPY49635.1 - 1 9.3 8.6 4.7 7.1 0.1 2.3 2 0 0 2 2 2 0 B-box zinc finger zf-ribbon_3 PF13248.1 EPY49635.1 - 6.7 6.0 8.4 11 5.3 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Ribosomal_L7Ae PF01248.21 EPY49636.1 - 1e-23 82.6 1.2 1.8e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L7Ae PF01248.21 EPY49637.1 - 1e-23 82.6 1.2 1.8e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sld5 PF05916.6 EPY49639.1 - 4.1e-11 43.1 0.0 5.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein DUF1752 PF08550.5 EPY49640.1 - 5e-07 29.1 5.3 1.1e-06 28.0 3.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AAA_18 PF13238.1 EPY49641.1 - 1.2e-07 32.0 0.0 7e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EPY49641.1 - 4e-07 29.8 0.0 5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EPY49641.1 - 4.2e-07 30.8 0.0 1.2e-06 29.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPY49641.1 - 1.4e-06 27.5 0.0 5.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EPY49641.1 - 0.0011 18.7 0.2 0.0058 16.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EPY49641.1 - 0.0019 18.2 0.1 0.0032 17.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EPY49641.1 - 0.0021 17.7 0.1 0.0044 16.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EPY49641.1 - 0.0027 16.6 0.0 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ArgK PF03308.11 EPY49641.1 - 0.0032 16.2 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_33 PF13671.1 EPY49641.1 - 0.0035 17.2 0.4 0.042 13.7 0.0 2.5 2 1 1 3 3 3 1 AAA domain KAP_NTPase PF07693.9 EPY49641.1 - 0.0038 16.2 0.0 0.0044 16.0 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_28 PF13521.1 EPY49641.1 - 0.0039 17.1 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EPY49641.1 - 0.0059 15.5 0.0 0.0089 14.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 EPY49641.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPY49641.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EPY49641.1 - 0.041 13.3 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EPY49641.1 - 0.051 13.7 0.1 0.12 12.5 0.0 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EPY49641.1 - 0.054 13.7 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EPY49641.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EPY49641.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KTI12 PF08433.5 EPY49641.1 - 0.094 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 EPY49641.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPY49641.1 - 0.1 12.7 0.6 0.44 10.6 0.2 2.1 1 1 1 2 2 2 0 AAA domain CoaE PF01121.15 EPY49641.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase RNA_helicase PF00910.17 EPY49641.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 EPY49641.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Thymidylate_kin PF02223.12 EPY49641.1 - 0.12 11.6 0.0 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.12 EPY49641.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Tom7 PF08038.7 EPY49642.1 - 0.074 12.5 0.7 0.14 11.5 0.5 1.4 1 0 0 1 1 1 0 TOM7 family TatC PF00902.13 EPY49642.1 - 0.35 10.2 4.2 0.45 9.8 2.9 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) CCDC-167 PF15188.1 EPY49643.1 - 0.016 15.1 0.1 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3784 PF12650.2 EPY49643.1 - 0.075 12.9 0.3 0.075 12.9 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) NifU_N PF01592.11 EPY49644.1 - 4.2e-52 175.4 0.1 5.6e-52 174.9 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain WD40 PF00400.27 EPY49645.1 - 7.2e-56 184.2 22.7 2.3e-09 36.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EPY49645.1 - 1e-09 37.5 0.1 1.8e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EPY49645.1 - 3.5e-09 36.6 0.0 0.0019 17.9 0.0 3.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PRKCSH PF07915.8 EPY49646.1 - 1.5e-07 32.0 2.0 1.1e-06 29.3 0.3 2.8 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 EPY49646.1 - 0.0041 16.4 0.1 0.0058 15.9 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Prefoldin_2 PF01920.15 EPY49647.1 - 1.1e-25 89.4 10.0 1.2e-25 89.2 6.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit Mnd1 PF03962.10 EPY49647.1 - 0.0061 16.2 2.7 0.0093 15.6 1.9 1.3 1 1 0 1 1 1 1 Mnd1 family DUF479 PF04336.7 EPY49647.1 - 0.028 14.5 3.0 0.25 11.4 1.7 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF479 V_ATPase_I PF01496.14 EPY49647.1 - 0.049 11.5 2.2 0.067 11.0 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.6 EPY49647.1 - 0.057 12.8 11.9 0.71 9.2 2.7 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 DASH_Dad3 PF08656.5 EPY49647.1 - 0.062 12.9 3.6 0.36 10.5 0.6 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Cortex-I_coil PF09304.5 EPY49647.1 - 0.083 12.9 6.1 0.14 12.1 3.5 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil ATG_C PF09333.6 EPY49647.1 - 0.089 12.9 0.8 5.2 7.2 0.1 2.1 1 1 1 2 2 2 0 ATG C terminal domain Prefoldin PF02996.12 EPY49647.1 - 0.11 12.1 6.6 30 4.2 4.6 2.1 1 1 0 1 1 1 0 Prefoldin subunit DUF4618 PF15397.1 EPY49647.1 - 0.12 11.7 7.4 0.14 11.4 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) RepL PF05732.6 EPY49647.1 - 0.14 11.3 3.0 0.39 9.9 2.1 1.7 1 1 0 1 1 1 0 Firmicute plasmid replication protein (RepL) adh_short_C2 PF13561.1 EPY49647.1 - 0.15 11.8 0.3 0.17 11.6 0.2 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF1706 PF08020.6 EPY49647.1 - 0.17 11.3 2.0 0.37 10.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) DUF3585 PF12130.3 EPY49647.1 - 0.24 11.2 4.0 4.5 7.1 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3585) TSC22 PF01166.13 EPY49647.1 - 0.28 11.1 3.4 6.5 6.8 0.1 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family YgaB PF14182.1 EPY49647.1 - 0.33 11.2 7.4 0.99 9.6 0.4 2.7 1 1 1 2 2 2 0 YgaB-like protein DUF2205 PF10224.4 EPY49647.1 - 0.37 10.3 5.6 5.7 6.5 0.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Tho2 PF11262.3 EPY49647.1 - 0.47 9.4 5.0 0.22 10.5 1.0 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF948 PF06103.6 EPY49647.1 - 0.61 9.9 3.6 3.4 7.6 0.1 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EPY49647.1 - 0.75 9.6 3.7 13 5.6 2.5 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FTA4 PF13093.1 EPY49647.1 - 0.77 9.1 6.8 1.7 8.0 4.5 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF904 PF06005.7 EPY49647.1 - 0.8 10.0 8.4 1.3 9.4 0.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EPY49647.1 - 0.8 10.0 7.0 7.6 6.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 EPY49647.1 - 0.81 9.5 7.4 1.8 8.4 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin like IncA PF04156.9 EPY49647.1 - 0.82 9.2 9.7 3.2 7.2 6.7 1.8 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EPY49647.1 - 0.98 9.2 6.1 5.2 6.9 0.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EPY49647.1 - 1.3 9.1 7.4 2.4 8.3 1.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2935 PF11155.3 EPY49647.1 - 1.6 8.8 4.9 3.1 7.8 3.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Spc24 PF08286.6 EPY49647.1 - 1.6 8.4 6.5 1.7 8.3 0.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EPY49647.1 - 2.2 7.8 9.1 4.8 6.7 2.1 2.2 2 0 0 2 2 2 0 Septum formation initiator RasGAP_C PF03836.10 EPY49647.1 - 2.7 7.6 7.8 9.2 5.9 5.4 1.8 1 1 0 1 1 1 0 RasGAP C-terminus Snf7 PF03357.16 EPY49647.1 - 2.8 7.3 9.6 1.4 8.2 1.0 2.1 1 1 1 2 2 2 0 Snf7 ADIP PF11559.3 EPY49647.1 - 3.1 7.6 8.9 8.9 6.1 2.4 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EPY49647.1 - 3.3 7.4 10.2 39 3.9 7.1 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.8 EPY49647.1 - 3.3 8.4 8.1 13 6.5 1.5 2.2 1 1 0 2 2 2 0 Occludin homology domain DUF4337 PF14235.1 EPY49647.1 - 4 7.2 6.7 16 5.2 4.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Mur_ligase_M PF08245.7 EPY49648.1 - 2.5e-09 37.4 0.4 8.6e-09 35.7 0.3 1.9 1 1 0 1 1 1 1 Mur ligase middle domain zf-CCCH PF00642.19 EPY49649.1 - 6.6e-16 57.5 20.6 2.4e-07 30.2 0.4 4.3 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPY49649.1 - 0.026 14.5 0.2 0.026 14.5 0.2 4.3 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Viral_cys_rich PF08008.7 EPY49649.1 - 0.19 11.3 2.8 2.3 7.8 0.6 2.4 2 1 0 2 2 2 0 Viral cysteine rich LUC7 PF03194.10 EPY49649.1 - 3 7.2 5.3 7.3 6.0 0.1 2.4 2 1 1 3 3 3 0 LUC7 N_terminus WD40 PF00400.27 EPY49650.1 - 9.2e-11 41.1 1.7 0.42 10.5 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Yip1 PF04893.12 EPY49651.1 - 7.9e-12 45.0 11.9 1.5e-11 44.1 8.2 1.5 1 1 0 1 1 1 1 Yip1 domain Prefoldin_2 PF01920.15 EPY49652.1 - 2.2e-19 69.1 8.3 2.6e-19 68.9 5.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 EPY49652.1 - 0.019 14.7 1.9 0.019 14.7 1.3 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fusion_gly PF00523.13 EPY49652.1 - 0.14 10.2 0.4 0.15 10.0 0.3 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 DASH_Spc19 PF08287.6 EPY49652.1 - 0.32 10.5 5.3 0.58 9.7 3.4 1.7 1 1 0 1 1 1 0 Spc19 DUF4047 PF13256.1 EPY49652.1 - 0.66 9.9 3.8 0.39 10.6 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Tropomyosin_1 PF12718.2 EPY49652.1 - 0.8 9.5 9.7 1.3 8.8 6.7 1.3 1 1 0 1 1 1 0 Tropomyosin like XhlA PF10779.4 EPY49652.1 - 3.8 7.4 6.3 1.2 9.1 1.0 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Autophagy_act_C PF03987.10 EPY49653.1 - 7.8e-08 32.3 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Mito_carr PF00153.22 EPY49654.1 - 2.2e-64 213.1 0.9 4.6e-23 80.7 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Rrp15p PF07890.7 EPY49655.1 - 6.3e-29 100.6 3.6 6.3e-29 100.6 2.5 2.0 2 0 0 2 2 2 1 Rrp15p DUF1454 PF07305.7 EPY49655.1 - 0.019 14.0 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) MADF_DNA_bdg PF10545.4 EPY49655.1 - 0.58 10.3 3.1 1.8 8.7 2.1 2.1 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EXS PF03124.9 EPY49656.1 - 2e-66 224.3 26.1 2.3e-66 224.1 18.1 1.0 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.8 EPY49656.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA SLX9 PF15341.1 EPY49657.1 - 1.6e-20 73.7 12.0 1.6e-20 73.7 8.3 1.7 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 Minor_capsid_1 PF10665.4 EPY49657.1 - 0.033 14.0 0.2 0.054 13.3 0.2 1.3 1 0 0 1 1 1 0 Minor capsid protein Med2 PF11214.3 EPY49657.1 - 0.3 11.1 6.5 0.31 11.0 0.3 2.6 1 1 2 3 3 3 0 Mediator complex subunit 2 Syntaxin-6_N PF09177.6 EPY49657.1 - 3.9 7.9 9.3 5.9 7.3 5.8 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Dopey_N PF04118.9 EPY49658.1 - 4.6e-96 321.2 0.2 2.9e-95 318.6 0.1 2.5 1 0 0 1 1 1 1 Dopey, N-terminal MBOAT PF03062.14 EPY49659.1 - 1.4e-45 155.8 43.5 1.9e-45 155.3 28.1 2.3 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Vma12 PF11712.3 EPY49659.1 - 3.8 7.2 8.4 0.54 9.9 2.5 2.1 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-DNL PF05180.7 EPY49660.1 - 3.2e-29 100.4 2.5 6.1e-29 99.5 1.8 1.5 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EPY49660.1 - 0.0097 15.5 1.3 0.017 14.8 0.9 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like HypA PF01155.14 EPY49660.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 EPY49660.1 - 0.15 11.7 0.9 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 EPY49660.1 - 0.33 10.6 6.8 15 5.3 4.6 2.4 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EPY49660.1 - 1.4 8.8 4.8 4.6 7.1 0.2 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.17 EPY49661.1 - 1.4e-154 515.8 18.2 1.8e-154 515.5 12.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPY49661.1 - 6.8e-30 102.7 4.0 4.4e-29 100.1 0.9 3.3 3 0 0 3 3 3 1 Cullin protein neddylation domain Hexokinase_2 PF03727.11 EPY49662.1 - 6e-95 317.0 0.0 7.8e-95 316.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPY49662.1 - 3.5e-79 264.9 0.0 5.1e-79 264.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Rhodanese PF00581.15 EPY49663.1 - 6.3e-14 52.2 0.2 2e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 Rhodanese-like domain SLD3 PF08639.5 EPY49664.1 - 6.6e-37 127.2 25.8 6.6e-37 127.2 17.9 2.1 2 1 0 2 2 2 1 DNA replication regulator SLD3 RhoGEF PF00621.15 EPY49666.1 - 1.7e-34 119.2 0.0 5.1e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain DAHP_synth_1 PF00793.15 EPY49667.1 - 1.7e-103 345.0 0.1 2.1e-103 344.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Sulfate_transp PF00916.15 EPY49668.1 - 4e-54 183.5 2.7 6.8e-54 182.7 1.9 1.4 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EPY49668.1 - 6.2e-13 48.3 0.0 1.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EPY49668.1 - 8e-09 34.9 0.2 1.6e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 STAS domain ThiF PF00899.16 EPY49669.1 - 5.4e-37 126.6 0.6 1.1e-36 125.6 0.0 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EPY49669.1 - 1.3e-22 79.1 0.6 2.8e-22 78.0 0.4 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPY49669.1 - 7.8e-16 57.1 2.7 7.8e-16 57.1 1.9 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E2_bind PF08825.5 EPY49669.1 - 1.4e-13 50.4 0.4 3.4e-13 49.1 0.3 1.6 1 0 0 1 1 1 1 E2 binding domain MoeZ_MoeB PF05237.8 EPY49669.1 - 0.0015 18.0 1.9 0.0033 16.9 0.0 2.3 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EPY49669.1 - 0.0041 17.2 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Prolamin_like PF05617.6 EPY49669.1 - 0.054 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Prolamin-like DUF221 PF02714.10 EPY49670.1 - 4.5e-101 337.9 17.5 4.5e-101 337.9 12.2 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPY49670.1 - 1.9e-44 150.9 2.8 1.9e-44 150.9 2.0 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPY49670.1 - 3.6e-19 68.4 0.0 1e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EPY49670.1 - 2.2e-14 53.7 4.3 2.2e-14 53.7 3.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) AKNA PF12443.3 EPY49670.1 - 0.12 12.3 4.0 0.087 12.8 0.7 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor Arrestin_N PF00339.24 EPY49671.1 - 4.2e-06 26.6 0.0 7.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF2477 PF10631.4 EPY49671.1 - 0.024 14.8 1.1 0.024 14.8 0.7 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2477) UPF0227 PF05728.7 EPY49671.1 - 0.2 11.3 0.9 0.47 10.1 0.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Amino_oxidase PF01593.19 EPY49672.1 - 3.9e-27 95.4 0.0 3.7e-20 72.4 0.0 2.9 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.12 EPY49672.1 - 1.6e-12 47.3 0.0 7.5e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.1 EPY49672.1 - 6.5e-06 26.0 0.0 2.1e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EPY49672.1 - 0.00013 22.1 0.7 0.00049 20.3 0.5 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box NAD_binding_9 PF13454.1 EPY49672.1 - 0.0086 15.8 0.0 1.4 8.6 0.0 3.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EPY49672.1 - 0.024 13.5 0.1 0.065 12.1 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPY49672.1 - 0.03 14.3 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GATA PF00320.22 EPY49674.1 - 2.3e-30 103.6 19.4 1.2e-16 59.6 2.4 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EPY49674.1 - 0.0095 15.2 8.6 0.43 9.9 0.2 2.8 2 0 0 2 2 2 2 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 EPY49674.1 - 0.11 12.1 10.8 0.5 10.0 0.7 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 HypA PF01155.14 EPY49674.1 - 2.7 7.7 5.3 3.2 7.4 0.3 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Mre11_DNA_bind PF04152.9 EPY49675.1 - 5.9e-54 182.5 0.4 5.9e-54 182.5 0.3 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EPY49675.1 - 4.9e-29 101.1 1.1 4.9e-29 101.1 0.8 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPY49675.1 - 6.5e-07 29.3 0.0 3e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ABC_sub_bind PF04392.7 EPY49675.1 - 0.038 12.9 0.6 0.057 12.3 0.1 1.5 2 0 0 2 2 2 0 ABC transporter substrate binding protein PGM_PMM_I PF02878.11 EPY49676.1 - 2e-15 56.4 0.0 1.4e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 EPY49676.1 - 1.1e-11 44.5 0.2 3.2e-11 43.0 0.2 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 EPY49676.1 - 7e-10 39.1 0.0 2.4e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EPY49676.1 - 9e-05 22.4 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III GATase PF00117.23 EPY49677.1 - 4.2e-13 49.1 0.0 5.6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPY49677.1 - 0.0046 16.4 0.1 0.024 14.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 EPY49677.1 - 0.0068 16.0 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Tht1 PF04163.7 EPY49678.1 - 6.9e-57 193.0 25.7 8.8e-57 192.7 17.8 1.0 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein UPF0118 PF01594.11 EPY49678.1 - 0.0032 16.5 1.3 0.0032 16.5 0.9 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF20 WW PF00397.21 EPY49679.1 - 5.2e-14 51.7 7.2 6.1e-07 29.1 1.2 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.14 EPY49679.1 - 5.3e-11 42.3 3.8 9.2e-11 41.5 0.0 3.1 4 0 0 4 4 4 1 FF domain Proteasome PF00227.21 EPY49680.1 - 1.6e-58 197.1 0.0 1.9e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPY49680.1 - 3.9e-14 51.6 0.2 7e-14 50.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RhoGEF PF00621.15 EPY49681.1 - 8.6e-30 103.9 0.6 2.9e-29 102.2 0.4 2.0 1 0 0 1 1 1 1 RhoGEF domain DUF2036 PF09724.4 EPY49682.1 - 6.1e-38 130.7 6.5 1.6e-37 129.3 4.5 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF3337 PF11816.3 EPY49683.1 - 5.3e-49 167.4 0.2 1.8e-45 155.7 1.9 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EPY49683.1 - 2.3e-22 78.0 27.5 2.1e-08 33.6 0.1 7.2 6 1 0 6 6 6 4 WD domain, G-beta repeat SNARE PF05739.14 EPY49684.1 - 0.12 12.1 0.0 0.99 9.1 0.0 1.9 2 0 0 2 2 2 0 SNARE domain Arrestin_C PF02752.17 EPY49685.1 - 8.9e-24 84.1 0.0 3.9e-21 75.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPY49685.1 - 2.3e-20 72.9 0.0 5.8e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EPY49685.1 - 0.00027 20.5 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Copper-fist PF00649.13 EPY49686.1 - 1.5e-19 68.9 1.8 1.5e-19 68.9 1.3 3.0 3 0 0 3 3 3 1 Copper fist DNA binding domain Ran-binding PF05508.6 EPY49687.1 - 1.5e-89 299.9 0.5 2.6e-89 299.1 0.3 1.3 1 0 0 1 1 1 1 RanGTP-binding protein Endotoxin_M PF00555.14 EPY49687.1 - 0.059 13.2 4.0 0.36 10.6 2.8 2.1 1 1 0 1 1 1 0 delta endotoxin Mem_trans PF03547.13 EPY49687.1 - 0.099 10.9 2.2 0.14 10.4 1.5 1.2 1 0 0 1 1 1 0 Membrane transport protein WD40 PF00400.27 EPY49688.1 - 4.8e-15 54.7 2.4 2.7e-07 30.2 0.0 4.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Vps16_N PF04841.8 EPY49689.1 - 6.6e-129 430.0 0.2 1.8e-128 428.6 0.0 1.7 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 EPY49689.1 - 1.4e-113 379.0 6.2 1.4e-113 379.0 4.3 1.6 2 0 0 2 2 2 1 Vps16, C-terminal region DnaJ PF00226.26 EPY49690.1 - 3.9e-08 32.8 0.0 6.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EPY49690.1 - 3.6e-07 30.0 0.2 1e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EPY49690.1 - 0.057 12.7 0.4 0.15 11.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Lactamase_B PF00753.22 EPY49691.1 - 4.5e-27 94.9 0.3 5.7e-27 94.6 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPY49691.1 - 7.9e-07 28.8 0.2 1.4e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPY49691.1 - 0.00046 19.9 0.2 0.00086 19.0 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EPY49691.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family GDA1_CD39 PF01150.12 EPY49692.1 - 1.2e-95 320.5 0.0 1.6e-95 320.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EPY49692.1 - 0.25 10.4 0.3 1.7 7.7 0.1 2.0 1 1 0 2 2 2 0 Ppx/GppA phosphatase family DUF2034 PF10356.4 EPY49693.1 - 2.5e-31 108.2 0.0 5.9e-16 58.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EPY49693.1 - 5.3e-12 45.5 0.0 7.8e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease PGAP1 PF07819.8 EPY49694.1 - 1.8e-77 259.9 0.0 2.7e-77 259.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPY49694.1 - 0.00033 20.4 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY49694.1 - 0.015 15.1 0.1 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY49694.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PI3_PI4_kinase PF00454.22 EPY49695.1 - 4.5e-38 131.0 0.2 8.9e-38 130.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-C3HC4 PF00097.20 EPY49696.1 - 5.3e-06 25.9 7.1 4e-05 23.1 4.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY49696.1 - 5.8e-06 25.9 9.8 9.5e-06 25.2 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPY49696.1 - 4.1e-05 23.5 9.0 0.00011 22.1 6.0 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY49696.1 - 4.2e-05 23.1 9.3 0.00042 19.9 6.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY49696.1 - 0.00067 19.4 7.9 0.0011 18.7 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EPY49696.1 - 0.0074 15.5 0.9 0.0095 15.1 0.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 EPY49696.1 - 0.0086 15.9 3.2 0.0086 15.9 2.2 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPY49696.1 - 0.012 15.7 3.4 0.019 15.0 2.3 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPY49696.1 - 0.034 13.8 4.1 0.034 13.8 2.8 2.8 3 1 1 4 4 3 0 RING-type zinc-finger Nairovirus_M PF07948.6 EPY49696.1 - 0.06 11.4 1.9 0.075 11.1 1.3 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like DZR PF12773.2 EPY49696.1 - 0.3 10.9 7.6 5 7.0 5.5 2.3 1 1 2 3 3 3 0 Double zinc ribbon zf-RING_4 PF14570.1 EPY49696.1 - 0.37 10.3 4.1 1.3 8.6 3.1 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EPY49696.1 - 0.38 10.6 4.0 0.7 9.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.1 EPY49696.1 - 2.5 7.9 5.2 7.4 6.4 3.6 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 EPY49696.1 - 3.3 7.6 8.7 14 5.7 6.1 1.9 1 1 1 2 2 2 0 FYVE zinc finger IBR PF01485.16 EPY49696.1 - 6.5 6.7 11.0 23 4.9 6.2 2.6 1 1 1 2 2 2 0 IBR domain WD40 PF00400.27 EPY49697.1 - 1.7e-16 59.3 9.0 1.8e-05 24.4 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Aconitase PF00330.15 EPY49698.1 - 2.6e-71 240.5 0.0 5.3e-44 150.4 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPY49698.1 - 7.2e-25 87.6 0.0 1.3e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain IPPT PF01715.12 EPY49699.1 - 8.5e-64 214.9 0.0 1.7e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 EPY49699.1 - 1.6e-06 28.9 0.0 5.5e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 EPY49699.1 - 4.6e-06 25.9 0.1 3.3e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Isopentenyl transferase AAA_18 PF13238.1 EPY49699.1 - 6.9e-05 23.1 0.3 0.001 19.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EPY49699.1 - 7.7e-05 22.5 0.4 0.00054 19.8 0.0 2.5 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 EPY49699.1 - 0.0039 17.3 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPY49699.1 - 0.0039 16.2 0.0 0.0097 15.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin zf-met PF12874.2 EPY49699.1 - 0.0097 16.0 1.0 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRK PF00485.13 EPY49699.1 - 0.015 14.8 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 EPY49699.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EPY49699.1 - 0.12 12.2 3.2 0.12 12.2 0.0 2.6 3 0 0 3 3 3 0 Shikimate kinase Hpr_kinase_C PF07475.7 EPY49699.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain zf-C2H2_jaz PF12171.3 EPY49699.1 - 0.14 12.3 0.2 0.14 12.3 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding IF-2B PF01008.12 EPY49700.1 - 1.8e-69 233.8 0.0 2.2e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Orbi_VP3 PF01700.11 EPY49700.1 - 4.4e-05 21.1 0.0 5.5e-05 20.8 0.0 1.1 1 0 0 1 1 1 1 Orbivirus VP3 (T2) protein Lum_binding PF00677.12 EPY49700.1 - 0.04 13.8 0.2 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Lumazine binding domain GatB_N PF02934.10 EPY49701.1 - 4.7e-101 337.4 0.0 6.5e-101 336.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EPY49701.1 - 5.4e-27 94.3 0.0 8.3e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 GatB domain Ferritin_2 PF13668.1 EPY49702.1 - 8.1e-13 48.4 0.8 5.6e-12 45.7 0.5 2.1 1 1 0 1 1 1 1 Ferritin-like domain PLU-1 PF08429.6 EPY49703.1 - 2.2e-66 224.0 18.5 6.5e-61 206.0 11.3 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EPY49703.1 - 7.1e-27 93.9 0.0 6.7e-26 90.7 0.0 2.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.24 EPY49703.1 - 9.2e-20 70.0 46.4 4.4e-08 32.7 6.6 4.2 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.11 EPY49703.1 - 1.2e-10 41.2 0.4 1.2e-10 41.2 0.2 3.4 2 0 0 2 2 2 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 EPY49703.1 - 0.0029 17.2 3.1 0.0029 17.2 2.1 4.4 5 0 0 5 5 5 2 Prokaryotic RING finger family 1 C1_1 PF00130.17 EPY49703.1 - 0.0074 15.9 32.1 0.51 10.1 2.1 4.5 4 0 0 4 4 4 3 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EPY49703.1 - 0.42 9.8 19.7 1.1 8.5 0.8 3.6 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_3 PF13922.1 EPY49703.1 - 8.4 6.7 15.1 0.28 11.4 0.3 3.3 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx MTHFR PF02219.12 EPY49704.1 - 1.7e-111 371.9 0.0 2.4e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase SEP PF08059.8 EPY49705.1 - 4e-25 87.9 0.1 2.7e-24 85.2 0.0 2.4 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EPY49705.1 - 1.2e-10 41.2 0.1 2.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EPY49705.1 - 3.4e-05 23.2 0.6 7.1e-05 22.2 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain Ribosomal_S6 PF01250.12 EPY49706.1 - 1.9e-10 40.4 0.0 3.4e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S6 RRM_1 PF00076.17 EPY49707.1 - 8.6e-27 92.5 0.5 9.5e-13 47.5 0.2 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49707.1 - 9.6e-23 79.9 0.1 6.5e-10 38.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49707.1 - 1.2e-14 53.8 3.7 4.8e-07 29.5 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Scramblase PF03803.10 EPY49708.1 - 7e-73 244.3 0.0 8.7e-73 244.0 0.0 1.1 1 0 0 1 1 1 1 Scramblase ATP-synt_ab PF00006.20 EPY49709.1 - 8.1e-114 378.4 0.0 1.1e-113 378.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPY49709.1 - 1.6e-23 83.3 0.7 3.4e-23 82.2 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPY49709.1 - 8.6e-15 54.7 0.9 2.3e-14 53.3 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EPY49709.1 - 0.082 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EPY49710.1 - 1.4e-42 142.0 14.3 9.3e-09 34.8 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EPY49710.1 - 0.0005 19.8 0.1 0.41 10.3 0.0 3.3 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF249 PF03158.8 EPY49710.1 - 0.015 14.8 0.2 0.043 13.3 0.0 1.8 2 0 0 2 2 2 0 Multigene family 530 protein BBS2_Mid PF14783.1 EPY49710.1 - 0.072 12.8 0.0 1.8 8.3 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region zf-Apc11 PF12861.2 EPY49711.1 - 9.8e-46 153.5 10.3 1.1e-45 153.4 7.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EPY49711.1 - 1.1e-30 105.5 10.2 1.2e-30 105.3 7.1 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPY49711.1 - 1.9e-07 30.7 13.4 1.9e-06 27.5 9.3 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPY49711.1 - 1e-05 25.4 5.0 1e-05 25.4 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY49711.1 - 7.7e-05 22.3 9.9 0.0022 17.7 7.1 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EPY49711.1 - 0.012 15.1 3.4 0.022 14.2 2.4 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EPY49711.1 - 0.013 15.0 11.8 0.069 12.8 8.2 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EPY49711.1 - 0.073 12.8 0.5 0.073 12.8 0.4 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-HC5HC2H_2 PF13832.1 EPY49711.1 - 0.29 11.1 7.2 0.52 10.3 5.0 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EPY49711.1 - 2 8.4 16.1 9.4 6.2 10.6 2.6 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 EPY49711.1 - 3.2 7.8 10.5 0.83 9.7 4.2 2.2 2 1 0 2 2 2 0 RING-variant domain Ribosomal_L19 PF01245.15 EPY49712.1 - 4.9e-23 81.0 0.0 6.9e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 GHMP_kinases_N PF00288.21 EPY49713.1 - 1.5e-10 40.9 0.5 4.1e-10 39.5 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPY49713.1 - 6.1e-06 26.3 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GIY-YIG PF01541.19 EPY49714.1 - 4.1e-08 33.4 0.0 2.8e-07 30.8 0.0 2.2 1 1 1 2 2 2 1 GIY-YIG catalytic domain DUF1900 PF08954.6 EPY49714.1 - 0.035 13.6 0.3 0.12 11.8 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1900) zf-RING_2 PF13639.1 EPY49714.1 - 4.8 7.0 11.2 9.7 6.1 7.7 1.5 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 EPY49714.1 - 8.9 6.0 15.0 0.73 9.5 6.5 2.2 3 0 0 3 3 3 0 PHD-finger Nop10p PF04135.7 EPY49715.1 - 2.3e-22 78.4 1.1 2.6e-22 78.2 0.7 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Hid1 PF12722.2 EPY49716.1 - 9.6e-124 414.0 29.5 1.9e-123 413.0 20.5 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EPY49716.1 - 8e-31 106.8 0.2 2.3e-30 105.3 0.2 1.7 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Pkinase PF00069.20 EPY49717.1 - 2e-67 227.0 0.0 2.7e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49717.1 - 1.3e-25 89.9 0.0 2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49717.1 - 8.6e-07 28.1 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPY49717.1 - 0.0027 16.8 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_VP8_L4R PF04498.7 EPY49717.1 - 0.063 12.5 0.1 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Poxvirus nucleic acid binding protein VP8/L4R UQ_con PF00179.21 EPY49718.1 - 4.2e-48 162.3 0.1 5.5e-48 161.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EPY49718.1 - 6.9e-05 22.5 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EPY49718.1 - 0.001 18.9 0.1 0.0018 18.1 0.0 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EPY49718.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B SPRY PF00622.23 EPY49719.1 - 5.3e-28 97.5 1.1 9e-28 96.8 0.8 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EPY49719.1 - 7.5e-16 58.1 5.4 1.6e-15 57.0 3.7 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPY49719.1 - 0.00015 21.3 0.0 0.00045 19.8 0.0 1.8 1 0 0 1 1 1 1 LisH RabGAP-TBC PF00566.13 EPY49720.1 - 1.1e-40 139.4 2.0 1.1e-40 139.4 1.4 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 EPY49720.1 - 8.1e-11 41.2 1.9 9.8e-11 41.0 0.3 1.9 2 0 0 2 2 2 1 GRAM domain Peptidase_M22 PF00814.20 EPY49721.1 - 3.7e-67 226.6 0.0 4.5e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family UPF0075 PF03702.9 EPY49721.1 - 0.032 13.1 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) MutL PF13941.1 EPY49721.1 - 0.061 11.6 0.0 0.09 11.0 0.0 1.1 1 0 0 1 1 1 0 MutL protein Biotin_lipoyl PF00364.17 EPY49722.1 - 8e-21 73.4 0.7 1.7e-20 72.4 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EPY49722.1 - 0.00046 19.7 0.0 0.00098 18.7 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EPY49722.1 - 0.00093 18.8 0.1 0.0039 16.8 0.0 2.0 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EPY49722.1 - 0.063 13.6 0.3 3.7 7.9 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein DUF2457 PF10446.4 EPY49723.1 - 2.1e-17 63.0 5.3 2.1e-17 63.0 3.7 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) SDA1 PF05285.7 EPY49723.1 - 0.00088 18.6 9.9 0.0031 16.8 6.9 1.8 1 1 0 1 1 1 1 SDA1 Rxt3 PF08642.5 EPY49724.1 - 5e-22 78.3 8.5 9e-16 58.1 0.1 3.2 3 1 1 4 4 4 2 Histone deacetylation protein Rxt3 LCCL PF03815.14 EPY49724.1 - 0.0002 21.2 0.0 0.00064 19.6 0.0 1.9 1 0 0 1 1 1 1 LCCL domain Mitochondr_Som1 PF11093.3 EPY49725.1 - 0.04 13.7 0.2 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial export protein Som1 GAGA PF09237.6 EPY49725.1 - 0.68 9.5 3.1 3.8 7.1 0.1 2.2 1 1 1 2 2 2 0 GAGA factor TAF8_C PF10406.4 EPY49726.1 - 2.3e-18 65.9 1.2 3.8e-18 65.2 0.9 1.3 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Methyltransf_22 PF13383.1 EPY49726.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ino80_Iec3 PF14612.1 EPY49728.1 - 3.1e-11 43.7 0.1 5.9e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling TFIIS_C PF01096.13 EPY49729.1 - 3e-17 61.9 1.1 3e-17 61.9 0.8 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPY49729.1 - 6.2e-17 60.9 8.1 2.4e-13 49.5 0.4 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.2 EPY49729.1 - 8.1e-06 25.5 9.2 0.0016 18.2 0.5 2.7 2 1 1 3 3 3 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EPY49729.1 - 1.8e-05 23.7 9.8 0.78 9.0 0.0 3.8 3 1 0 3 3 3 3 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EPY49729.1 - 0.00016 21.0 14.8 0.28 10.7 0.8 3.5 3 1 0 3 3 3 3 zinc-ribbon domain Lar_restr_allev PF14354.1 EPY49729.1 - 0.00026 21.2 1.2 0.00026 21.2 0.9 2.8 1 1 1 2 2 2 1 Restriction alleviation protein Lar C1_1 PF00130.17 EPY49729.1 - 0.00076 19.1 5.6 0.0011 18.7 0.4 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIB PF13453.1 EPY49729.1 - 0.0019 17.3 8.3 0.002 17.2 0.6 2.3 2 0 0 2 2 2 1 Transcription factor zinc-finger Terminase_GpA PF05876.7 EPY49729.1 - 0.0019 16.6 0.4 0.0019 16.6 0.3 1.4 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) zinc_ribbon_4 PF13717.1 EPY49729.1 - 0.002 17.8 9.3 5.1 6.8 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPY49729.1 - 0.0035 16.8 9.7 4.5 6.9 0.4 4.2 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 EPY49729.1 - 0.004 16.8 7.9 0.24 11.0 0.2 3.0 2 1 0 2 2 2 1 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EPY49729.1 - 0.011 15.3 8.9 0.63 9.7 0.5 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 EPY49729.1 - 0.014 15.0 14.4 0.087 12.5 0.2 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 VP_N-CPKC PF11475.3 EPY49729.1 - 0.027 14.0 3.8 2.7 7.6 0.1 3.0 3 0 0 3 3 2 0 Virion protein N terminal domain Prok-RING_1 PF14446.1 EPY49729.1 - 0.027 14.1 6.1 0.92 9.2 0.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.1 EPY49729.1 - 0.031 13.9 2.9 1.5 8.5 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-DNA_Pol PF08996.5 EPY49729.1 - 0.034 13.5 6.2 0.04 13.2 0.7 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF3797 PF12677.2 EPY49729.1 - 0.061 12.9 10.6 0.58 9.8 1.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3797) Ogr_Delta PF04606.7 EPY49729.1 - 0.062 12.9 1.4 0.062 12.9 1.0 2.9 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Ribosomal_S27e PF01667.12 EPY49729.1 - 0.08 12.4 8.6 0.086 12.4 0.0 3.3 3 1 1 4 4 4 0 Ribosomal protein S27 Nudix_N_2 PF14803.1 EPY49729.1 - 0.081 12.6 11.1 2.7 7.7 2.4 4.1 3 1 0 3 3 3 0 Nudix N-terminal Zn_ribbon_recom PF13408.1 EPY49729.1 - 0.093 13.0 6.5 3.5 7.9 0.2 2.8 2 2 0 2 2 2 0 Recombinase zinc beta ribbon domain CNP1 PF08750.6 EPY49729.1 - 0.11 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CNP1-like family TF_Zn_Ribbon PF08271.7 EPY49729.1 - 0.12 11.6 14.5 1 8.7 3.2 3.4 3 1 0 3 3 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EPY49729.1 - 0.12 12.1 11.0 0.13 12.0 1.9 3.3 2 2 1 3 3 3 0 Transposase zinc-ribbon domain DUF164 PF02591.10 EPY49729.1 - 0.13 12.0 3.1 9.2 6.1 0.0 3.7 4 0 0 4 4 4 0 Putative zinc ribbon domain zf-AN1 PF01428.11 EPY49729.1 - 0.17 11.7 9.3 3 7.7 0.8 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger DUF2387 PF09526.5 EPY49729.1 - 0.19 11.6 0.3 0.19 11.6 0.2 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc-ribbons_6 PF07191.7 EPY49729.1 - 0.21 11.3 9.2 0.34 10.7 0.5 2.9 2 1 1 3 3 3 0 zinc-ribbons Rubredoxin PF00301.15 EPY49729.1 - 0.22 11.4 8.3 7 6.6 0.1 3.6 4 0 0 4 4 3 0 Rubredoxin zf-FPG_IleRS PF06827.9 EPY49729.1 - 0.24 11.0 13.5 3.7 7.2 0.4 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Baculo_LEF5_C PF11792.3 EPY49729.1 - 0.26 10.6 7.6 0.6 9.5 0.0 3.7 4 0 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain zf-C2H2_4 PF13894.1 EPY49729.1 - 0.28 11.6 12.9 0.7 10.3 0.9 3.8 4 0 0 4 4 3 0 C2H2-type zinc finger zf-MYND PF01753.13 EPY49729.1 - 0.3 10.9 7.9 1 9.3 1.2 2.7 2 1 0 2 2 2 0 MYND finger YhfH PF14149.1 EPY49729.1 - 0.33 10.7 9.5 3.2 7.6 0.9 3.3 3 0 0 3 3 3 0 YhfH-like protein zf-ISL3 PF14690.1 EPY49729.1 - 0.36 10.8 8.5 4.4 7.4 0.1 3.7 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PolC_DP2 PF03833.8 EPY49729.1 - 0.41 8.2 6.0 0.22 9.1 0.4 2.0 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 GFA PF04828.9 EPY49729.1 - 0.47 10.4 10.3 1.6 8.7 0.6 3.4 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EPY49729.1 - 0.49 10.2 6.8 1.1 9.2 1.2 2.9 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RecR PF02132.10 EPY49729.1 - 0.67 9.4 13.2 0.2 11.1 2.0 3.5 3 1 0 3 3 3 0 RecR protein Zn-ribbon_8 PF09723.5 EPY49729.1 - 0.73 9.8 17.3 3.7 7.5 0.4 3.8 2 2 1 4 4 4 0 Zinc ribbon domain DUF2072 PF09845.4 EPY49729.1 - 0.74 9.7 7.0 2 8.3 0.1 3.1 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) zf-RING_3 PF14369.1 EPY49729.1 - 0.82 9.7 9.3 9.3 6.3 0.0 3.7 3 1 0 3 3 3 0 zinc-finger Nop10p PF04135.7 EPY49729.1 - 0.87 9.3 0.1 0.87 9.3 0.1 2.8 3 1 1 4 4 3 0 Nucleolar RNA-binding protein, Nop10p family RNHCP PF12647.2 EPY49729.1 - 0.9 9.4 6.2 2.5 7.9 1.9 2.7 1 1 1 2 2 2 0 RNHCP domain DUF2082 PF09855.4 EPY49729.1 - 0.96 9.3 0.1 0.96 9.3 0.0 3.5 3 1 0 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) IBR PF01485.16 EPY49729.1 - 1 9.2 10.9 0.75 9.7 0.9 2.6 2 2 0 2 2 2 0 IBR domain zf-LITAF-like PF10601.4 EPY49729.1 - 1.2 9.0 9.5 5.2 7.0 0.1 4.0 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain zf-C4_Topoisom PF01396.14 EPY49729.1 - 1.3 8.5 15.6 0.35 10.4 1.1 4.0 3 1 1 4 4 4 0 Topoisomerase DNA binding C4 zinc finger Stc1 PF12898.2 EPY49729.1 - 1.5 8.9 7.0 0.7 9.9 0.5 2.2 1 1 1 2 2 2 0 Stc1 domain PhnA_Zn_Ribbon PF08274.7 EPY49729.1 - 2.4 7.9 11.6 31 4.4 2.1 4.0 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zf-C4pol PF14260.1 EPY49729.1 - 2.5 8.1 7.5 46 4.0 4.2 2.6 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-CHY PF05495.7 EPY49729.1 - 3 8.0 9.1 4.4 7.5 0.3 2.8 2 1 0 2 2 2 0 CHY zinc finger zf-C2H2 PF00096.21 EPY49729.1 - 3.2 8.2 15.1 0.58 10.6 0.8 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2HC5 PF06221.8 EPY49729.1 - 3.3 7.5 8.2 7.6 6.3 0.3 2.9 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type DUF2296 PF10058.4 EPY49729.1 - 3.6 7.3 7.2 14 5.5 0.0 3.4 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C2H2_6 PF13912.1 EPY49729.1 - 3.8 7.5 17.1 0.61 10.0 0.3 4.2 4 1 0 4 4 4 0 C2H2-type zinc finger PADR1 PF08063.7 EPY49729.1 - 4.4 6.7 10.6 2.5 7.5 0.1 3.4 3 1 0 3 3 3 0 PADR1 (NUC008) domain CpXC PF14353.1 EPY49729.1 - 4.5 7.2 10.9 10 6.1 1.7 3.4 2 2 1 3 3 3 0 CpXC protein RRN7 PF11781.3 EPY49729.1 - 5.5 6.5 10.7 31 4.1 0.1 3.9 3 1 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 C1_4 PF07975.7 EPY49729.1 - 5.7 7.0 12.4 11 6.0 1.6 3.3 2 2 0 2 2 2 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.6 EPY49729.1 - 6 6.7 13.3 3.2 7.6 0.1 3.6 2 2 2 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like ADK_lid PF05191.9 EPY49729.1 - 6.1 6.6 8.5 36 4.1 0.0 3.7 4 0 0 4 4 4 0 Adenylate kinase, active site lid Opy2 PF09463.5 EPY49729.1 - 7.1 6.8 12.9 22 5.2 0.0 3.5 3 1 0 3 3 3 0 Opy2 protein Elf1 PF05129.8 EPY49729.1 - 8.2 6.2 9.0 0.51 10.0 0.7 2.7 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like Peptidase_M28 PF04389.12 EPY49730.1 - 1.8e-28 99.4 0.0 2.8e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPY49730.1 - 0.058 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Ribosomal_S13 PF00416.17 EPY49731.1 - 2.8e-40 137.0 2.8 3.4e-40 136.8 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPY49731.1 - 0.00072 18.2 0.0 0.0011 17.5 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EPY49731.1 - 0.0094 15.9 0.2 0.027 14.5 0.0 1.8 2 1 0 2 2 2 1 Helix-hairpin-helix motif PWI PF01480.12 EPY49732.1 - 6.1e-28 96.7 0.1 1.3e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 PWI domain Acetyltransf_1 PF00583.19 EPY49733.1 - 2e-12 46.9 0.0 3.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPY49733.1 - 3.8e-08 33.4 0.0 4.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPY49733.1 - 1.1e-07 31.9 1.6 1.2e-07 31.8 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY49733.1 - 9.2e-06 25.3 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EPY49733.1 - 0.00016 21.6 0.1 0.00036 20.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY49733.1 - 0.00057 19.7 0.0 0.00098 18.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain ATE_C PF04377.10 EPY49733.1 - 0.027 14.5 0.4 0.04 13.9 0.3 1.2 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Acetyltransf_CG PF14542.1 EPY49733.1 - 0.064 13.1 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EPY49733.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acyl_transf_3 PF01757.17 EPY49733.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase family SNARE PF05739.14 EPY49734.1 - 5.5e-17 61.2 2.5 5.5e-17 61.2 1.7 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EPY49734.1 - 1.3e-15 57.3 8.4 8.4e-15 54.8 2.6 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EPY49734.1 - 8.3e-06 25.4 6.4 0.0035 16.9 1.8 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.6 EPY49734.1 - 0.0017 15.9 0.2 0.0017 15.9 0.2 2.0 1 1 1 2 2 2 1 Prominin BLOC1_2 PF10046.4 EPY49734.1 - 0.012 15.7 1.5 5.3 7.2 0.1 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med4 PF10018.4 EPY49734.1 - 0.018 14.4 0.2 0.018 14.4 0.2 2.7 2 1 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.7 EPY49734.1 - 0.021 15.0 6.2 0.23 11.7 0.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Vac_Fusion PF02346.11 EPY49734.1 - 0.034 13.5 1.3 2 7.9 0.0 3.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Vps51 PF08700.6 EPY49734.1 - 0.039 13.7 1.0 0.43 10.4 0.0 2.9 2 1 1 3 3 3 0 Vps51/Vps67 Allexi_40kDa PF05549.6 EPY49734.1 - 0.045 13.0 4.8 0.048 12.9 0.7 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein V-SNARE PF05008.10 EPY49734.1 - 0.059 13.5 0.6 0.059 13.5 0.4 3.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF4094 PF13334.1 EPY49734.1 - 0.064 13.6 3.5 0.091 13.1 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Skp1 PF01466.14 EPY49734.1 - 0.36 10.8 3.0 0.22 11.5 0.5 1.9 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Herpes_US9 PF06072.6 EPY49734.1 - 0.44 10.4 2.1 1.1 9.1 1.4 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3732 PF12532.3 EPY49734.1 - 0.49 9.8 5.3 0.26 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3732) DUF3647 PF12363.3 EPY49734.1 - 0.55 10.3 2.6 1.9 8.5 0.1 2.7 2 1 0 2 2 2 0 Phage protein PRKCSH-like PF12999.2 EPY49735.1 - 3.8e-64 215.4 7.9 3.8e-64 215.4 5.5 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EPY49735.1 - 8.7e-54 181.1 1.2 1.7e-53 180.2 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF3585 PF12130.3 EPY49735.1 - 0.022 14.6 10.4 0.017 14.9 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) DUF948 PF06103.6 EPY49735.1 - 0.35 10.7 4.3 1.8 8.4 0.0 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Ldl_recept_a PF00057.13 EPY49735.1 - 0.37 10.7 24.9 0.47 10.3 8.2 2.9 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A Snapin_Pallidin PF14712.1 EPY49735.1 - 2 8.7 9.3 5.1 7.4 0.0 3.6 3 1 0 3 3 3 0 Snapin/Pallidin MscS_porin PF12795.2 EPY49735.1 - 3 7.1 15.1 1.4 8.1 4.5 3.0 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain ABC_tran PF00005.22 EPY49736.1 - 2.2e-40 138.1 0.0 5.9e-21 75.2 0.0 4.0 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 EPY49736.1 - 4.4e-18 66.2 14.6 3.5e-06 27.2 0.0 5.3 5 0 0 5 5 5 4 AAA domain ABC_tran_2 PF12848.2 EPY49736.1 - 1.8e-08 34.1 7.9 1.8e-08 34.1 5.5 4.9 3 1 2 5 5 4 1 ABC transporter AAA_29 PF13555.1 EPY49736.1 - 8.3e-07 28.4 0.1 0.02 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EPY49736.1 - 4.2e-06 27.0 0.0 0.03 14.5 0.1 3.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EPY49736.1 - 8.3e-06 26.2 1.5 0.061 13.8 0.0 4.0 4 0 0 4 4 2 2 Miro-like protein AAA_22 PF13401.1 EPY49736.1 - 1.6e-05 25.0 0.1 0.024 14.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPY49736.1 - 4.6e-05 23.0 0.1 0.18 11.5 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain SMC_N PF02463.14 EPY49736.1 - 5.3e-05 22.5 23.6 0.0004 19.6 0.1 5.3 5 2 1 6 6 5 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EPY49736.1 - 0.00011 21.4 0.0 0.019 14.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EPY49736.1 - 0.00013 21.6 0.1 0.015 14.9 0.1 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPY49736.1 - 0.00014 21.7 0.2 0.012 15.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPY49736.1 - 0.00018 20.9 0.1 0.58 9.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPY49736.1 - 0.00043 20.3 1.9 0.033 14.1 0.1 3.2 2 2 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EPY49736.1 - 0.00043 20.1 0.3 0.61 10.0 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EPY49736.1 - 0.00068 20.0 0.5 0.022 15.0 0.0 5.5 5 2 0 6 6 5 2 AAA domain FtsK_SpoIIIE PF01580.13 EPY49736.1 - 0.00089 18.7 0.0 0.029 13.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EPY49736.1 - 0.0013 18.4 0.0 0.27 10.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EPY49736.1 - 0.0036 17.2 0.1 2.1 8.2 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EPY49736.1 - 0.004 17.1 0.0 0.28 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPY49736.1 - 0.0046 16.4 0.1 0.1 12.0 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EPY49736.1 - 0.0049 16.3 4.7 0.47 9.8 0.0 3.9 4 1 1 5 5 4 1 AAA-like domain NTPase_1 PF03266.10 EPY49736.1 - 0.0088 15.7 0.4 0.28 10.8 0.1 2.6 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.18 EPY49736.1 - 0.01 15.7 0.0 0.58 10.1 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EPY49736.1 - 0.012 15.3 0.1 0.87 9.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPY49736.1 - 0.033 15.0 0.0 0.033 15.0 0.0 4.3 4 1 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 EPY49736.1 - 0.039 14.1 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EPY49736.1 - 0.087 13.1 0.0 0.087 13.1 0.0 4.8 5 1 0 5 5 4 0 AAA domain HA2 PF04408.18 EPY49737.1 - 3.4e-14 52.7 0.7 1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) RWD PF05773.17 EPY49737.1 - 2.3e-12 46.8 1.1 7.8e-12 45.0 0.8 2.0 1 0 0 1 1 1 1 RWD domain Helicase_C PF00271.26 EPY49737.1 - 3.1e-12 46.1 0.1 9.2e-12 44.6 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPY49737.1 - 1.8e-11 43.8 0.1 4.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EPY49737.1 - 1.7e-07 30.8 0.5 6.2e-07 29.0 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase UBA PF00627.26 EPY49737.1 - 0.00028 20.6 0.4 0.012 15.4 0.0 3.1 3 0 0 3 3 3 1 UBA/TS-N domain AAA_22 PF13401.1 EPY49737.1 - 0.00041 20.4 0.1 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EPY49737.1 - 0.0028 16.6 0.0 0.005 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EPY49737.1 - 0.014 15.3 0.1 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Zot PF05707.7 EPY49737.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EPY49737.1 - 0.028 14.1 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EPY49737.1 - 0.063 12.3 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.1 EPY49737.1 - 0.09 12.3 0.2 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HEAT PF02985.17 EPY49739.1 - 6e-08 32.1 0.3 0.046 13.8 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat DUF3091 PF11291.3 EPY49739.1 - 0.019 14.9 0.2 0.063 13.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) TAN PF11640.3 EPY49739.1 - 0.021 14.5 0.1 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.1 EPY49739.1 - 0.23 11.9 2.2 12 6.4 0.0 4.1 3 2 2 5 5 5 0 HEAT-like repeat Carla_C4 PF01623.12 EPY49739.1 - 0.33 10.7 3.0 1.7 8.4 0.4 2.4 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein DUF904 PF06005.7 EPY49739.1 - 9.9 6.5 17.7 0.96 9.7 4.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) WD40 PF00400.27 EPY49740.1 - 4.5e-55 181.6 14.4 3.3e-07 29.9 0.0 11.5 12 0 0 12 12 12 7 WD domain, G-beta repeat CPSF_A PF03178.10 EPY49740.1 - 0.11 11.5 0.1 0.46 9.5 0.0 2.1 3 0 0 3 3 3 0 CPSF A subunit region eIF2A PF08662.6 EPY49740.1 - 0.16 11.7 4.0 33 4.1 0.0 4.4 4 2 2 6 6 6 0 Eukaryotic translation initiation factor eIF2A FH2 PF02181.18 EPY49741.1 - 3.8e-52 177.4 0.1 3.8e-52 177.4 0.1 2.4 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EPY49741.1 - 3.8e-19 68.8 0.4 1.3e-18 67.1 0.3 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EPY49741.1 - 2.2e-07 30.3 0.2 2.2e-07 30.3 0.2 2.5 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Syntaxin-18_N PF10496.4 EPY49742.1 - 5e-09 35.8 0.7 2.9e-08 33.4 0.0 2.5 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EPY49742.1 - 0.0058 16.3 0.9 0.027 14.1 0.7 2.2 1 0 0 1 1 1 1 SNARE domain Suppressor_APC PF11414.3 EPY49742.1 - 0.34 10.7 7.9 2.1 8.1 5.5 2.4 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein AIP3 PF03915.8 EPY49742.1 - 0.61 8.9 11.2 2.2 7.0 7.8 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 KIAA1430 PF13879.1 EPY49742.1 - 0.98 9.8 7.8 0.44 10.9 1.0 2.6 2 1 0 2 2 2 0 KIAA1430 homologue Fib_alpha PF08702.5 EPY49742.1 - 5.7 7.0 9.1 1.4 9.0 1.3 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Sua5_yciO_yrdC PF01300.13 EPY49743.1 - 2e-51 173.7 0.0 3.1e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EPY49743.1 - 1.8e-29 102.3 0.0 2.9e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding LRR_8 PF13855.1 EPY49743.1 - 0.066 12.9 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Leucine rich repeat Mad3_BUB1_I PF08311.7 EPY49744.1 - 3.9e-45 152.7 2.3 8.1e-45 151.6 1.6 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 DUF4573 PF15140.1 EPY49744.1 - 0.0078 15.8 0.4 0.015 14.8 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4573) Troponin PF00992.15 EPY49744.1 - 0.015 15.3 0.4 0.025 14.6 0.3 1.3 1 0 0 1 1 1 0 Troponin TPR_8 PF13181.1 EPY49744.1 - 0.45 10.4 3.1 1.3 8.9 2.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Na_Ca_ex PF01699.19 EPY49745.1 - 2.5e-42 143.7 39.5 1.3e-22 79.9 9.3 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1109 PF06532.6 EPY49745.1 - 0.0044 16.4 5.1 0.0044 16.4 3.5 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1109) ATP-synt_8 PF00895.15 EPY49745.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.5 3 1 1 4 4 4 0 ATP synthase protein 8 Nuc_sug_transp PF04142.10 EPY49746.1 - 8.9e-92 306.5 14.3 8.9e-92 306.5 9.9 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 EPY49746.1 - 2.5e-10 39.7 15.3 3.2e-10 39.4 10.6 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EPY49746.1 - 2.3e-06 27.8 2.4 2.3e-06 27.8 1.7 2.5 2 0 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EPY49746.1 - 2.6e-05 23.8 25.9 6.7e-05 22.5 1.7 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EPY49746.1 - 7.3e-05 22.8 2.8 7.3e-05 22.8 2.0 3.3 2 1 0 2 2 2 1 EamA-like transporter family DUF2534 PF10749.4 EPY49746.1 - 9 6.2 11.0 7.5 6.5 4.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2534) Proteasome PF00227.21 EPY49747.1 - 1e-45 155.3 0.0 1.2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPY49747.1 - 1.7e-09 36.8 0.4 3.5e-09 35.8 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ADK PF00406.17 EPY49748.1 - 1e-39 135.7 0.0 1.2e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EPY49748.1 - 7.3e-11 42.4 0.0 1.6e-10 41.3 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EPY49748.1 - 2.1e-06 28.5 0.0 3.1e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EPY49748.1 - 8.2e-06 25.3 0.1 0.026 13.8 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EPY49748.1 - 0.00011 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPY49748.1 - 0.065 12.3 0.0 0.076 12.0 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EPY49748.1 - 0.11 12.4 0.1 0.48 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain DIM PF08194.7 EPY49749.1 - 0.03 14.2 0.5 0.044 13.7 0.4 1.2 1 0 0 1 1 1 0 DIM protein Ribosomal_S13 PF00416.17 EPY49750.1 - 8.1e-28 96.9 0.0 1e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPY49750.1 - 0.013 14.0 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HSA PF07529.8 EPY49751.1 - 1.2e-18 66.6 2.2 2.2e-18 65.8 0.2 2.4 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 EPY49751.1 - 4.6e-12 45.8 0.3 1.7e-11 44.0 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPY49751.1 - 0.005 16.8 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Asp PF00026.18 EPY49752.1 - 7.3e-30 104.3 3.8 9.6e-30 103.9 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPY49752.1 - 2.3e-05 24.3 0.0 0.0024 17.8 0.0 3.0 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Erv26 PF04148.8 EPY49753.1 - 2.4e-50 170.8 8.9 2.8e-34 118.3 0.8 2.0 1 1 1 2 2 2 2 Transmembrane adaptor Erv26 DEAD PF00270.24 EPY49754.1 - 1.4e-44 151.5 0.0 8.3e-44 149.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY49754.1 - 4.3e-27 93.7 0.1 9.5e-27 92.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY49754.1 - 0.036 13.9 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EPY49754.1 - 0.052 11.9 0.0 0.11 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) PBP1_TM PF14812.1 EPY49755.1 - 0.023 14.9 0.1 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EPY49755.1 - 0.086 12.6 0.4 0.1 12.4 0.3 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2362 PF10154.4 EPY49756.1 - 0.13 10.8 2.3 0.16 10.5 1.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) cobW PF02492.14 EPY49758.1 - 3.9e-26 91.5 0.0 5.3e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Sigma70_r4 PF04545.11 EPY49758.1 - 0.07 12.4 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 Methyltransf_4 PF02390.12 EPY49759.1 - 2e-51 173.8 0.0 2.6e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPY49759.1 - 4.7e-05 23.9 0.0 8.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EPY49759.1 - 0.0004 19.4 0.0 0.001 18.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_25 PF13649.1 EPY49759.1 - 0.00098 19.4 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY49759.1 - 0.0011 19.4 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY49759.1 - 0.0015 17.9 0.0 0.0031 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EPY49759.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY49759.1 - 0.003 17.1 0.0 0.0064 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY49759.1 - 0.01 16.3 0.1 0.031 14.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EPY49759.1 - 0.044 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase AICARFT_IMPCHas PF01808.13 EPY49760.1 - 1.7e-118 395.2 0.0 2.2e-118 394.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EPY49760.1 - 1.7e-24 85.5 0.0 3.5e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF999 PF06198.6 EPY49762.1 - 1.3e-10 41.2 4.4 1.1e-09 38.2 2.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF999) Pox_A9 PF04835.7 EPY49762.1 - 7.3 6.5 7.8 1.8 8.5 0.1 2.5 2 1 0 2 2 2 0 A9 protein conserved region PH PF00169.24 EPY49763.1 - 4.3e-22 78.2 2.2 3.6e-10 39.9 0.5 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EPY49763.1 - 0.00051 20.2 6.7 0.71 10.1 0.3 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EPY49763.1 - 0.01 15.7 0.7 0.86 9.5 0.1 2.4 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology CPSase_L_D3 PF02787.14 EPY49763.1 - 0.021 14.5 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DNA_pol_A PF00476.15 EPY49764.1 - 1.5e-89 300.3 0.0 2.2e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EPY49764.1 - 1.7e-05 24.3 0.0 0.0027 17.2 0.0 2.6 2 0 0 2 2 2 2 3'-5' exonuclease TIM PF00121.13 EPY49765.1 - 1.1e-86 289.8 0.5 1.3e-86 289.6 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CENP-K PF11802.3 EPY49765.1 - 0.13 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Centromere-associated protein K DUF2462 PF09495.5 EPY49767.1 - 9.2e-13 48.7 10.5 1.1e-12 48.5 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Lum_binding PF00677.12 EPY49767.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 Lumazine binding domain BRF1 PF07741.8 EPY49767.1 - 1.5 9.0 5.5 2.4 8.4 3.8 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain EMP24_GP25L PF01105.19 EPY49768.1 - 1.2e-43 148.9 0.4 1.2e-43 148.9 0.3 1.3 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD PIN_4 PF13638.1 EPY49770.1 - 1.4e-23 83.4 0.0 2.5e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 PIN domain XLF PF09302.6 EPY49771.1 - 4.9e-22 78.5 1.2 5.8e-22 78.2 0.8 1.1 1 0 0 1 1 1 1 XLF (XRCC4-like factor) SH3_9 PF14604.1 EPY49772.1 - 1.2e-10 40.7 0.1 2.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPY49772.1 - 2.8e-08 33.0 0.0 5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPY49772.1 - 0.00057 19.3 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CGI-121 PF08617.5 EPY49773.1 - 4.4e-43 146.7 2.0 4.9e-43 146.5 1.4 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 THOC7 PF05615.8 EPY49774.1 - 1.3e-16 61.1 8.4 1.3e-16 61.1 5.8 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 DUF1049 PF06305.6 EPY49774.1 - 0.0092 15.4 2.4 0.14 11.6 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) XRCC4 PF06632.7 EPY49774.1 - 0.0099 14.7 1.7 0.0099 14.7 1.2 2.0 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Streptin-Immun PF11083.3 EPY49774.1 - 0.028 14.3 10.5 0.22 11.5 0.3 2.7 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein CENP-Q PF13094.1 EPY49774.1 - 0.093 12.7 22.4 1.3 9.0 2.2 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ax_dynein_light PF10211.4 EPY49774.1 - 0.11 12.2 14.3 0.032 14.0 4.1 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1189 PF06691.6 EPY49774.1 - 0.19 11.0 1.1 0.29 10.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Mnd1 PF03962.10 EPY49774.1 - 0.32 10.6 13.3 0.64 9.6 9.1 1.6 1 1 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 EPY49774.1 - 0.44 8.8 6.8 0.56 8.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 EPY49774.1 - 0.63 9.9 17.9 2.2 8.1 6.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EPY49774.1 - 0.68 9.7 13.2 0.61 9.9 1.1 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.1 EPY49774.1 - 1 8.2 5.4 1.4 7.8 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) E2R135 PF11570.3 EPY49774.1 - 1.1 9.3 7.9 0.19 11.8 1.0 2.2 2 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 CASP_C PF08172.7 EPY49774.1 - 3.7 6.4 12.5 37 3.2 8.6 2.2 1 1 0 1 1 1 0 CASP C terminal OmpH PF03938.9 EPY49774.1 - 5.4 6.9 20.1 11 5.8 1.4 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GrpE PF01025.14 EPY49774.1 - 5.8 6.4 14.3 0.23 11.0 1.0 2.5 2 1 0 2 2 2 0 GrpE BTV_NS2 PF04514.7 EPY49774.1 - 8.7 5.1 9.9 15 4.3 6.8 1.4 1 1 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AAA PF00004.24 EPY49775.1 - 2.8e-38 131.1 0.0 7.3e-38 129.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY49775.1 - 9.8e-08 32.2 0.4 4.8e-05 23.4 0.2 2.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EPY49775.1 - 4.3e-07 29.2 0.0 1.3e-06 27.6 0.0 1.8 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPY49775.1 - 1e-06 28.8 2.3 0.00068 19.6 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 EPY49775.1 - 1.4e-06 28.1 0.0 3.3e-06 27.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EPY49775.1 - 1.7e-06 27.7 0.2 9.5e-06 25.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPY49775.1 - 5e-06 27.3 0.0 2.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPY49775.1 - 3.7e-05 23.2 0.6 0.04 13.3 0.1 2.4 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EPY49775.1 - 0.00016 21.1 0.0 0.00042 19.7 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EPY49775.1 - 0.0002 21.2 0.1 0.001 18.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPY49775.1 - 0.00029 20.0 0.2 0.0008 18.6 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EPY49775.1 - 0.00066 19.8 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EPY49775.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EPY49775.1 - 0.00083 19.3 0.0 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EPY49775.1 - 0.00089 19.5 0.0 0.0029 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPY49775.1 - 0.001 18.2 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 EPY49775.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 EPY49775.1 - 0.0013 18.3 0.1 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EPY49775.1 - 0.0029 17.2 0.0 0.0067 16.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial dnaA protein NACHT PF05729.7 EPY49775.1 - 0.0031 17.1 0.1 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain DEAD PF00270.24 EPY49775.1 - 0.0043 16.5 0.0 0.14 11.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ATP-synt_ab PF00006.20 EPY49775.1 - 0.0052 16.3 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EPY49775.1 - 0.0057 15.4 0.0 0.0082 14.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 EPY49775.1 - 0.006 16.0 0.0 0.024 14.1 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain KaiC PF06745.8 EPY49775.1 - 0.009 15.1 0.0 0.61 9.1 0.0 2.4 1 1 1 2 2 2 1 KaiC AAA_21 PF13304.1 EPY49775.1 - 0.0099 15.8 1.1 2.6 7.9 0.3 2.3 1 1 1 2 2 2 1 AAA domain CPT PF07931.7 EPY49775.1 - 0.01 15.4 0.0 0.077 12.6 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 EPY49775.1 - 0.014 15.1 0.3 0.15 11.7 0.0 2.4 2 1 1 3 3 2 0 Archaeal ATPase Guanylate_kin PF00625.16 EPY49775.1 - 0.015 14.7 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase ABC_tran PF00005.22 EPY49775.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 EPY49775.1 - 0.022 14.2 0.0 0.077 12.4 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EPY49775.1 - 0.026 14.2 0.1 0.097 12.4 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain AAA_3 PF07726.6 EPY49775.1 - 0.027 14.0 0.1 0.096 12.2 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EPY49775.1 - 0.028 14.2 0.1 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase CDC37_N PF03234.9 EPY49775.1 - 0.05 13.9 0.4 5.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Parvo_NS1 PF01057.12 EPY49775.1 - 0.05 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EPY49775.1 - 0.052 13.1 0.2 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 EPY49775.1 - 0.059 12.2 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EPY49775.1 - 0.093 11.4 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 EPY49775.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EPY49775.1 - 0.13 11.6 0.1 0.83 9.0 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain Ribosomal_S17e PF00833.13 EPY49776.1 - 1.6e-61 205.4 1.0 1.8e-61 205.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S17 PdxJ PF03740.8 EPY49776.1 - 0.036 13.2 0.1 0.044 12.9 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ DIRP PF06584.8 EPY49776.1 - 0.07 12.9 0.2 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 DIRP Cryptochrome_C PF12546.3 EPY49776.1 - 0.11 13.1 0.1 0.16 12.6 0.1 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Myb_DNA-binding PF00249.26 EPY49777.1 - 7.2e-13 48.3 0.0 2.3e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EPY49777.1 - 9.2e-11 41.1 5.2 1.6e-10 40.3 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EPY49777.1 - 2.3e-08 34.0 1.2 6.5e-07 29.3 0.0 3.0 3 1 1 4 4 4 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EPY49777.1 - 1.5e-06 28.2 0.0 1.2e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.6 EPY49777.1 - 0.0011 18.7 2.6 0.0025 17.5 1.8 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Pkinase PF00069.20 EPY49778.1 - 1.5e-68 230.7 0.0 2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49778.1 - 3.7e-30 104.8 0.0 5.9e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPY49778.1 - 6.7e-10 39.3 1.0 1.9e-09 37.9 0.7 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPY49778.1 - 0.001 18.0 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EPY49778.1 - 0.064 13.1 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 C2 domain Choline_kinase PF01633.15 EPY49778.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-Tim10_DDP PF02953.10 EPY49780.1 - 8.7e-17 60.1 3.5 1.1e-16 59.8 2.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L50 PF10501.4 EPY49781.1 - 4.5e-05 23.3 0.0 0.00052 19.9 0.0 2.2 1 1 0 1 1 1 1 Ribosomal subunit 39S PEX11 PF05648.9 EPY49782.1 - 0.18 11.0 0.7 0.2 10.9 0.2 1.4 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) NAD_kinase PF01513.16 EPY49783.1 - 1.1e-51 175.3 0.0 1.4e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MCM PF00493.18 EPY49784.1 - 1.2e-139 464.8 0.4 1.7e-139 464.2 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPY49784.1 - 1.5e-25 90.0 1.1 1e-24 87.3 0.1 2.9 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPY49784.1 - 5.5e-06 25.6 0.0 0.00048 19.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPY49784.1 - 2.8e-05 23.8 0.0 7.5e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPY49784.1 - 9.3e-05 22.0 0.0 0.00094 18.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HHH_5 PF14520.1 EPY49784.1 - 0.028 14.5 0.2 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Elf1 PF05129.8 EPY49784.1 - 0.035 13.7 0.8 0.079 12.6 0.5 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Sigma54_activat PF00158.21 EPY49784.1 - 0.057 12.8 0.7 2.6 7.4 0.0 3.2 4 0 0 4 4 4 0 Sigma-54 interaction domain Proteasom_Rpn13 PF04683.8 EPY49785.1 - 1.4e-28 98.7 0.1 3.4e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor SNF5 PF04855.7 EPY49787.1 - 2.5e-63 213.7 0.7 1.7e-61 207.8 0.2 2.4 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EPY49787.1 - 3.8e-10 38.9 5.3 3.8e-10 38.9 3.7 2.7 2 0 0 2 2 2 1 GATA zinc finger LUC7 PF03194.10 EPY49788.1 - 4.8e-85 285.1 11.6 5.9e-85 284.8 8.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Snf7 PF03357.16 EPY49788.1 - 0.0026 17.1 2.9 0.004 16.5 1.5 1.7 1 1 0 1 1 1 1 Snf7 MAT1 PF06391.8 EPY49788.1 - 0.0075 15.8 3.7 0.0075 15.8 2.6 1.9 2 0 0 2 2 2 1 CDK-activating kinase assembly factor MAT1 MCPsignal PF00015.16 EPY49788.1 - 0.034 13.6 0.7 0.052 13.0 0.5 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0242 PF06785.6 EPY49788.1 - 0.31 9.6 8.6 0.27 9.8 4.4 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) Occludin_ELL PF07303.8 EPY49788.1 - 1.3 9.7 6.9 1.2 9.8 2.2 2.4 1 1 1 2 2 2 0 Occludin homology domain FliT PF05400.8 EPY49788.1 - 8.6 6.8 11.1 0.28 11.6 2.0 2.6 3 0 0 3 3 3 0 Flagellar protein FliT UCH PF00443.24 EPY49789.1 - 2.2e-74 249.9 0.0 4.6e-74 248.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY49789.1 - 2.2e-17 63.4 1.0 7.1e-08 32.2 0.2 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EPY49789.1 - 4.3e-12 46.2 1.5 9.1e-12 45.2 0.0 2.4 3 0 0 3 3 3 1 DUSP domain USP7_C2 PF14533.1 EPY49789.1 - 0.0011 18.4 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal PSRP-3_Ycf65 PF04839.8 EPY49789.1 - 0.017 15.1 0.0 0.054 13.5 0.0 1.9 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) DUF3785 PF12653.2 EPY49789.1 - 0.49 10.2 8.8 3.9 7.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3785) L31 PF09784.4 EPY49790.1 - 7.9e-42 141.5 0.4 8.9e-42 141.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cyt-b5 PF00173.23 EPY49791.1 - 2.8e-24 84.7 0.0 3.7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PGA2 PF07543.7 EPY49791.1 - 0.05 13.3 0.1 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Tim17 PF02466.14 EPY49792.1 - 1.9e-27 95.8 3.8 2.3e-27 95.5 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2953 PF11167.3 EPY49792.1 - 0.23 11.4 2.0 0.97 9.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) PX PF00787.19 EPY49793.1 - 3.7e-20 71.8 0.2 1e-19 70.3 0.1 1.8 2 0 0 2 2 2 1 PX domain Polyketide_cyc PF03364.15 EPY49794.1 - 9.5e-23 80.6 0.0 1.1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EPY49794.1 - 0.0013 18.9 0.0 0.0016 18.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Rbsn PF11464.3 EPY49794.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Glyco_transf_22 PF03901.12 EPY49795.1 - 2e-98 330.1 33.0 2.3e-98 329.9 22.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EPY49795.1 - 0.00023 21.0 10.2 0.00023 21.0 7.1 3.5 2 2 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ferric_reduct PF01794.14 EPY49796.1 - 0.00081 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Claudin_3 PF06653.6 EPY49796.1 - 0.0083 15.8 3.5 0.0083 15.8 2.4 1.4 2 0 0 2 2 2 1 Tight junction protein, Claudin-like DUF4153 PF13687.1 EPY49796.1 - 0.038 13.5 4.9 0.049 13.1 3.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) DUF4064 PF13273.1 EPY49796.1 - 0.063 13.3 5.0 0.32 11.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF1182 PF06681.8 EPY49796.1 - 0.086 12.0 4.7 0.041 13.0 1.9 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) DUF912 PF06024.7 EPY49796.1 - 6.7 6.8 6.9 1.3 9.1 1.4 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DIM1 PF02966.11 EPY49797.1 - 2.7e-68 227.6 0.5 3e-68 227.4 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EPY49797.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin 7TMR-DISM_7TM PF07695.6 EPY49798.1 - 0.011 15.3 1.6 0.015 14.9 1.1 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling YjgP_YjgQ PF03739.9 EPY49798.1 - 0.026 13.2 0.1 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF3169 PF11368.3 EPY49798.1 - 0.034 13.3 0.1 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2346 PF09803.4 EPY49798.1 - 0.075 12.8 0.3 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) Fig1 PF12351.3 EPY49798.1 - 0.092 12.6 0.9 0.11 12.3 0.6 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3671 PF12420.3 EPY49798.1 - 0.17 11.8 2.4 0.42 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function PXA PF02194.10 EPY49799.1 - 3.5e-36 124.5 0.2 3.5e-36 124.5 0.1 3.0 2 1 0 2 2 2 1 PXA domain PX PF00787.19 EPY49799.1 - 1.7e-19 69.6 0.4 1.7e-19 69.6 0.2 3.2 3 0 0 3 3 3 1 PX domain RGS PF00615.14 EPY49799.1 - 4.3e-18 65.5 0.8 4.3e-18 65.5 0.6 2.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain Nexin_C PF08628.7 EPY49799.1 - 0.00095 19.2 0.1 0.0046 17.0 0.0 2.3 1 1 0 1 1 1 1 Sorting nexin C terminal Pox_Ag35 PF03286.9 EPY49799.1 - 0.0029 17.1 1.0 0.006 16.1 0.7 1.5 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Spectrin PF00435.16 EPY49799.1 - 0.28 11.4 9.1 1.8 8.8 2.6 3.1 2 0 0 2 2 2 0 Spectrin repeat MRC1 PF09444.5 EPY49799.1 - 0.8 10.0 5.4 1.7 8.9 3.2 1.9 1 1 0 1 1 1 0 MRC1-like domain TMF_DNA_bd PF12329.3 EPY49799.1 - 1.2 9.0 9.5 3.1 7.6 0.3 3.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2009 PF09418.5 EPY49800.1 - 2e-193 643.3 0.2 2.2e-193 643.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) WD40 PF00400.27 EPY49801.1 - 2.5e-83 271.2 22.4 2.2e-11 43.1 0.1 11.7 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp13 PF08625.6 EPY49801.1 - 2.8e-42 143.7 0.0 4.6e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EPY49801.1 - 4.1e-06 25.2 10.1 0.23 9.5 0.0 5.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY49801.1 - 2.9e-05 22.9 4.6 0.61 8.7 0.0 4.5 2 2 2 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 EPY49801.1 - 0.0014 17.7 0.1 0.029 13.5 0.0 3.0 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EPY49801.1 - 0.0015 16.8 0.4 0.025 12.8 0.0 2.8 3 0 0 3 3 3 1 Cytochrome D1 heme domain Frag1 PF10277.4 EPY49802.1 - 2.9e-29 102.1 20.1 3.7e-29 101.7 13.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MARVEL PF01284.18 EPY49802.1 - 0.036 13.8 20.5 1.1 9.0 0.0 3.1 2 1 1 3 3 3 0 Membrane-associating domain DUF754 PF05449.6 EPY49802.1 - 0.061 13.3 7.0 1.2 9.2 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF754) DUF3671 PF12420.3 EPY49802.1 - 0.25 11.3 4.6 1.2 9.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function Tetraspannin PF00335.15 EPY49802.1 - 0.45 9.7 15.2 2.7 7.2 4.6 2.1 1 1 1 2 2 2 0 Tetraspanin family DUF1980 PF09323.5 EPY49802.1 - 0.55 9.9 2.2 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) NfeD PF01957.13 EPY49802.1 - 1.4 9.0 11.0 0.33 11.0 0.9 3.0 2 2 2 4 4 4 0 NfeD-like C-terminal, partner-binding Glycos_transf_4 PF00953.16 EPY49802.1 - 2.1 8.1 11.6 0.29 10.9 2.5 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 4 DUF3812 PF12757.2 EPY49803.1 - 5.8e-09 36.0 21.6 5.8e-09 36.0 15.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3812) Tom37_C PF11801.3 EPY49803.1 - 0.62 9.9 14.6 1.3 8.8 9.0 2.5 1 1 0 1 1 1 0 Tom37 C-terminal domain DnaJ PF00226.26 EPY49804.1 - 1.4e-20 72.7 0.2 2.6e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EPY49804.1 - 0.011 15.7 0.2 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Proteasome PF00227.21 EPY49805.1 - 9e-41 139.2 0.0 1e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CTP_transf_1 PF01148.15 EPY49806.1 - 5.9e-08 32.6 10.0 5.9e-08 32.6 6.9 3.2 1 1 2 3 3 3 1 Cytidylyltransferase family Pkinase PF00069.20 EPY49807.1 - 2.4e-58 197.3 0.0 4e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 EPY49807.1 - 1.9e-41 141.8 6.5 3e-41 141.2 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 EPY49807.1 - 3.3e-41 141.0 0.0 4.8e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY49807.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY49807.1 - 0.027 13.4 1.3 4.8 6.0 0.0 3.5 4 0 0 4 4 4 0 Kinase-like Thg1 PF04446.7 EPY49808.1 - 5.2e-47 158.8 0.1 7.4e-47 158.3 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EPY49808.1 - 1.6e-45 153.6 2.4 2.6e-45 153.0 1.7 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain WD40 PF00400.27 EPY49809.1 - 1.3e-09 37.5 2.2 7.4e-05 22.4 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat TAP42 PF04177.7 EPY49810.1 - 1.1e-72 244.8 21.9 1.8e-72 244.1 15.2 1.3 1 1 0 1 1 1 1 TAP42-like family Glyco_transf_5 PF08323.6 EPY49811.1 - 3.8e-16 59.3 0.1 6.4e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPY49811.1 - 5.4e-10 38.9 0.0 1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3395 PF11875.3 EPY49812.1 - 1.8e-32 112.0 1.4 1.8e-32 112.0 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EPY49812.1 - 7e-22 76.9 0.6 1.7e-21 75.7 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain Mod_r PF07200.8 EPY49812.1 - 0.72 9.7 10.3 0.02 14.7 2.4 1.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Alpha-amylase PF00128.19 EPY49813.1 - 4e-60 203.8 5.1 4e-60 203.8 3.6 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPY49813.1 - 1e-12 47.9 0.0 3e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) MRP-S31 PF15433.1 EPY49814.1 - 0.13 11.6 11.3 3 7.1 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF2076 PF09849.4 EPY49814.1 - 1 9.3 11.9 2 8.4 8.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pox_Ag35 PF03286.9 EPY49814.1 - 7.8 5.9 20.5 2.6 7.5 11.9 1.8 1 1 0 2 2 2 0 Pox virus Ag35 surface protein RP-C_C PF11800.3 EPY49814.1 - 8.7 5.9 9.7 12 5.5 6.4 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region Complex1_LYR_1 PF13232.1 EPY49815.1 - 2.9e-07 30.5 0.7 2.9e-07 30.5 0.5 3.3 3 1 0 3 3 3 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPY49815.1 - 1.2e-06 28.1 6.5 1.8e-06 27.6 0.8 3.2 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Cytochrom_B562 PF07361.6 EPY49815.1 - 0.05 14.0 3.1 0.062 13.7 0.7 2.1 2 0 0 2 2 2 0 Cytochrome b562 DUF1318 PF07027.7 EPY49815.1 - 0.076 13.2 0.8 4.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) DUF848 PF05852.6 EPY49815.1 - 0.78 9.5 4.5 0.77 9.6 0.1 2.3 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4441 PF14536.1 EPY49815.1 - 2.1 8.3 11.0 1.1 9.2 4.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4441) Sugar_tr PF00083.19 EPY49816.1 - 4.3e-41 140.9 13.3 3.6e-21 75.2 0.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPY49816.1 - 9.4e-22 77.1 27.2 1.2e-19 70.3 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF89 PF01937.14 EPY49817.1 - 2.2e-119 398.4 0.0 2.5e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF883 PF05957.8 EPY49818.1 - 0.019 15.3 0.6 0.019 15.3 0.4 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GlutR_dimer PF00745.15 EPY49818.1 - 0.046 13.6 0.2 0.065 13.1 0.1 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain MRP-L20 PF12824.2 EPY49819.1 - 6.2e-24 84.8 2.4 7.8e-24 84.4 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Toxin_YhaV PF11663.3 EPY49819.1 - 0.041 13.6 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 Toxin with endonuclease activity YhaV Sugarporin_N PF11471.3 EPY49819.1 - 0.45 10.1 3.2 0.81 9.3 2.2 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ctr PF04145.10 EPY49820.1 - 1e-32 113.1 8.0 1.7e-32 112.4 5.6 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Ten1 PF12658.2 EPY49821.1 - 5.2e-13 48.8 0.0 6.6e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EPY49821.1 - 0.00092 18.7 0.0 0.0036 16.8 0.0 1.8 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 EPY49821.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Replication factor A protein 3 DUF999 PF06198.6 EPY49822.1 - 1.3e-10 41.2 4.4 1.1e-09 38.2 2.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF999) Pox_A9 PF04835.7 EPY49822.1 - 7.3 6.5 7.8 1.8 8.5 0.1 2.5 2 1 0 2 2 2 0 A9 protein conserved region RWD PF05773.17 EPY49823.1 - 3.4e-18 65.5 1.7 3.4e-18 65.5 1.2 2.1 2 1 1 3 3 3 1 RWD domain DUF445 PF04286.7 EPY49823.1 - 0.00052 19.6 1.5 0.00063 19.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) IL28A PF15177.1 EPY49823.1 - 0.039 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Interleukin-28A VSG_B PF13206.1 EPY49823.1 - 0.073 12.1 3.3 0.094 11.8 2.3 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain SAMP PF05924.6 EPY49823.1 - 4.1 6.6 5.2 1.6 8.0 0.3 2.5 2 0 0 2 2 2 0 SAMP Motif Epimerase PF01370.16 EPY49824.1 - 2e-21 76.5 0.2 5.2e-21 75.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY49824.1 - 2.2e-14 52.8 0.0 4.3e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPY49824.1 - 1.6e-12 47.8 0.0 5.5e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPY49824.1 - 3e-08 32.9 0.1 3.2e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPY49824.1 - 3.6e-06 26.9 0.3 9e-05 22.4 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EPY49824.1 - 0.0001 21.6 0.5 0.00066 19.0 0.1 2.2 1 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EPY49824.1 - 0.00033 19.6 0.1 0.00053 18.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EPY49824.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.18 EPY49824.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EPY49824.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus KR PF08659.5 EPY49824.1 - 0.09 12.4 0.4 0.59 9.7 0.1 2.3 2 1 0 2 2 2 0 KR domain GATA PF00320.22 EPY49825.1 - 8.3e-29 98.6 15.8 5.9e-15 54.3 2.2 2.6 2 0 0 2 2 2 2 GATA zinc finger ArfGap PF01412.13 EPY49825.1 - 2.1e-05 24.2 2.9 0.015 15.1 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.12 EPY49825.1 - 0.0012 18.4 5.4 0.028 14.1 0.5 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EPY49825.1 - 0.0023 17.2 1.5 1.1 8.6 0.2 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 EPY49825.1 - 0.11 12.3 9.1 24 4.8 6.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 EPY49825.1 - 0.31 10.9 6.9 1.1 9.2 4.8 2.0 1 1 0 1 1 1 0 FYVE zinc finger NMD3 PF04981.8 EPY49825.1 - 0.41 9.7 5.4 4.1 6.4 0.4 2.1 1 1 1 2 2 2 0 NMD3 family Elf1 PF05129.8 EPY49825.1 - 0.76 9.5 7.2 0.082 12.6 0.3 2.5 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 EPY49825.1 - 1.2 8.4 8.1 1.2 8.4 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EPY49825.1 - 1.6 8.4 7.5 9.2 6.0 0.8 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RRN7 PF11781.3 EPY49825.1 - 6 6.4 9.2 0.19 11.2 0.2 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ipi1_N PF12333.3 EPY49827.1 - 4.1e-25 87.7 0.1 3.5e-24 84.6 0.0 2.7 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Rota_NSP4 PF01452.11 EPY49827.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non structural protein FTA4 PF13093.1 EPY49829.1 - 1.2e-32 113.0 14.7 1.4e-32 112.8 10.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Poty_PP PF08440.5 EPY49829.1 - 0.42 9.6 3.4 2.1 7.3 1.1 2.1 1 1 1 2 2 2 0 Potyviridae polyprotein AAA_23 PF13476.1 EPY49829.1 - 4.7 7.4 6.9 7.5 6.8 4.8 1.4 1 1 0 1 1 1 0 AAA domain Prefoldin PF02996.12 EPY49829.1 - 4.9 6.8 10.0 1.3 8.7 1.1 2.8 3 0 0 3 3 3 0 Prefoldin subunit Ribosomal_S19 PF00203.16 EPY49830.1 - 1.3e-30 104.7 0.1 1.8e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SPT2 PF08243.6 EPY49831.1 - 5.3e-25 87.9 8.5 5.3e-25 87.9 5.9 3.1 2 1 1 3 3 3 1 SPT2 chromatin protein DNA_pol_alpha_N PF12254.3 EPY49831.1 - 0.015 15.0 0.1 0.015 15.0 0.1 3.1 3 1 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal E1-E2_ATPase PF00122.15 EPY49832.1 - 7.1e-60 201.8 5.3 7.1e-60 201.8 3.6 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPY49832.1 - 1.1e-22 81.5 1.5 1.3e-22 81.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPY49832.1 - 6.3e-13 47.9 0.0 1.9e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPY49832.1 - 4.9e-12 46.4 0.0 1.3e-11 45.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPY49832.1 - 0.0035 16.9 0.1 0.0035 16.9 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY49832.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 EPY49832.1 - 0.036 13.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 DMRTA motif FixP_N PF14715.1 EPY49832.1 - 0.84 9.0 5.6 13 5.2 0.2 2.7 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Spc7 PF08317.6 EPY49833.1 - 1.3e-71 241.0 17.2 1.3e-71 241.0 11.9 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EPY49833.1 - 5.9e-05 22.6 0.1 0.00032 20.2 0.1 2.1 2 0 0 2 2 2 1 Spc7_C2 Cation_efflux PF01545.16 EPY49834.1 - 3.6e-41 141.1 4.5 4.5e-41 140.7 3.1 1.1 1 0 0 1 1 1 1 Cation efflux family RNA_pol_Rpb6 PF01192.17 EPY49835.1 - 7.9e-24 83.1 0.1 1.1e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Transaldolase PF00923.14 EPY49836.1 - 3.6e-98 328.2 0.5 4.1e-98 328.0 0.3 1.0 1 0 0 1 1 1 1 Transaldolase Metallophos PF00149.23 EPY49837.1 - 7.9e-15 54.7 0.0 2.1e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPY49837.1 - 2.2e-07 30.8 0.1 4e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Kelch_3 PF13415.1 EPY49837.1 - 0.025 14.7 0.3 0.079 13.1 0.2 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain TolA PF06519.6 EPY49837.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 TolA C-terminal HAD_2 PF13419.1 EPY49838.1 - 6.1e-18 65.6 0.0 7.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY49838.1 - 1.3e-08 35.4 0.0 6.3e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPY49838.1 - 0.00012 21.9 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPY49838.1 - 0.00043 19.9 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 EPY49838.1 - 0.0057 16.1 0.0 0.015 14.8 0.0 1.6 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Radical_SAM PF04055.16 EPY49839.1 - 2.6e-26 92.7 0.0 1.6e-25 90.1 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 EPY49839.1 - 4.2e-23 81.2 0.0 1.4e-22 79.5 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EPY49839.1 - 7.4e-14 51.9 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Pkinase PF00069.20 EPY49840.1 - 3.3e-60 203.4 0.0 6.6e-60 202.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49840.1 - 4e-21 75.2 0.0 6.4e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY49840.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY49840.1 - 0.16 10.9 0.0 0.32 9.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Rab5ip PF07019.7 EPY49841.1 - 6.7e-19 67.8 10.2 8.1e-19 67.5 7.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) XAP5 PF04921.9 EPY49842.1 - 2e-60 204.3 5.4 5.2e-60 202.9 3.7 1.8 1 1 0 1 1 1 1 XAP5, circadian clock regulator DDHD PF02862.12 EPY49843.1 - 2.1e-41 142.1 6.8 3.4e-40 138.2 3.6 2.5 2 1 0 2 2 2 1 DDHD domain FAM219A PF15260.1 EPY49843.1 - 0.013 15.8 0.3 0.037 14.3 0.2 1.8 1 0 0 1 1 1 0 Protein family FAM219A Abhydrolase_5 PF12695.2 EPY49843.1 - 0.02 14.6 0.0 0.046 13.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Nramp PF01566.13 EPY49843.1 - 0.2 10.4 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein UMP1 PF05348.6 EPY49845.1 - 1.9e-32 111.9 0.1 2.2e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Npa1 PF11707.3 EPY49846.1 - 1.2e-61 208.6 6.5 7.8e-61 205.8 3.7 2.8 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EPY49846.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Creb binding CoaE PF01121.15 EPY49847.1 - 2.3e-58 196.5 0.0 2.8e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EPY49847.1 - 8.5e-07 29.8 0.1 2.6e-06 28.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY49847.1 - 0.00057 20.1 0.1 0.0035 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY49847.1 - 0.00088 19.1 0.1 0.0036 17.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain ADK PF00406.17 EPY49847.1 - 0.036 13.9 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Adenylate kinase SKI PF01202.17 EPY49847.1 - 0.063 13.1 0.2 0.24 11.2 0.0 2.0 2 1 0 2 2 2 0 Shikimate kinase PRK PF00485.13 EPY49847.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EPY49847.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 EPY49848.1 - 6.7e-75 251.5 0.0 8.3e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49848.1 - 5.9e-37 127.1 0.0 7.6e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPY49848.1 - 6.2e-15 55.0 0.5 1.2e-14 54.1 0.3 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EPY49848.1 - 3.4e-09 36.0 0.0 8.3e-09 34.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EPY49848.1 - 5.1e-06 25.9 0.1 9.5e-06 25.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EPY49848.1 - 0.00054 19.7 0.0 0.25 11.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPY49848.1 - 0.0013 17.8 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.9 EPY49848.1 - 0.0065 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase WD40 PF00400.27 EPY49849.1 - 2.8e-31 106.2 19.4 6.6e-10 38.4 0.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EPY49849.1 - 1.5e-07 31.3 0.2 1e-05 25.3 0.1 2.8 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPY49849.1 - 4e-05 21.6 0.4 0.00018 19.5 0.0 2.1 3 0 0 3 3 3 1 IKI3 family Nucleoporin_N PF08801.6 EPY49849.1 - 0.0011 17.8 1.5 0.041 12.6 0.6 2.7 2 1 0 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EPY49849.1 - 0.0016 16.8 0.0 0.019 13.2 0.0 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain DUF2414 PF10309.4 EPY49850.1 - 0.072 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) tRNA-synt_1 PF00133.17 EPY49851.1 - 3.7e-154 514.0 0.0 4.9e-154 513.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPY49851.1 - 3.7e-25 88.4 0.0 9e-18 64.0 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPY49851.1 - 2.5e-22 79.2 0.4 4.5e-22 78.4 0.3 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EPY49851.1 - 0.00064 18.9 0.0 0.021 13.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 EPY49851.1 - 0.013 15.0 5.4 0.032 13.8 3.7 1.7 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Ran_BP1 PF00638.13 EPY49852.1 - 2.1e-20 73.0 0.1 5.5e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 EPY49852.1 - 8.7e-14 51.6 1.8 8.7e-14 51.6 1.3 3.7 5 0 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) VID27 PF08553.5 EPY49852.1 - 0.00039 18.8 0.3 0.00039 18.8 0.2 2.4 3 0 0 3 3 3 1 VID27 cytoplasmic protein CAF1A PF12253.3 EPY49852.1 - 9.8 6.3 12.9 0.64 10.1 1.7 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A eRF1_1 PF03463.10 EPY49853.1 - 4e-40 136.4 0.1 7.1e-40 135.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EPY49853.1 - 6.8e-32 110.5 0.2 1e-31 110.0 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPY49853.1 - 1.6e-23 83.0 0.0 3.2e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 DUF1938 PF09153.5 EPY49853.1 - 0.025 14.3 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Phos_pyr_kin PF08543.7 EPY49854.1 - 8.5e-59 198.7 0.3 1.1e-58 198.4 0.2 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 EPY49854.1 - 0.031 13.4 0.1 0.079 12.1 0.0 1.7 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Diphtheria_T PF02764.9 EPY49854.1 - 0.039 13.7 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Diphtheria toxin, T domain Ribosomal_S18 PF01084.15 EPY49855.1 - 1.1e-16 60.4 0.0 1.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.20 EPY49856.1 - 3.8e-49 167.1 0.0 5.5e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49856.1 - 3.1e-32 111.6 0.0 4.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49856.1 - 0.029 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EPY49856.1 - 0.057 13.1 0.1 0.26 10.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPY49856.1 - 0.34 9.6 0.1 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC2_membrane PF01061.19 EPY49857.1 - 2.7e-80 268.4 52.7 3.3e-42 144.0 15.1 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPY49857.1 - 5.2e-52 175.7 0.6 5.9e-18 65.4 0.0 4.4 4 0 0 4 4 4 3 ABC transporter PDR_CDR PF06422.7 EPY49857.1 - 1.1e-33 114.9 13.8 1.2e-29 102.0 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 EPY49857.1 - 1.3e-13 50.7 0.1 0.0002 20.8 0.0 4.2 5 0 0 5 5 4 2 AAA domain DUF258 PF03193.11 EPY49857.1 - 4.9e-12 45.3 2.1 0.00023 20.3 0.0 3.6 4 0 0 4 4 3 2 Protein of unknown function, DUF258 ABC_trans_N PF14510.1 EPY49857.1 - 1.2e-11 44.4 0.0 3.9e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EPY49857.1 - 3.4e-10 40.2 1.2 0.00066 19.7 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.7 EPY49857.1 - 5.3e-08 32.2 0.1 0.1 11.7 0.0 3.4 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.1 EPY49857.1 - 1.5e-07 31.6 0.8 0.052 13.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPY49857.1 - 4.9e-07 29.1 5.7 0.058 12.9 0.2 4.1 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EPY49857.1 - 7.4e-07 29.5 0.0 0.11 12.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EPY49857.1 - 1.5e-06 28.3 0.7 1.1 9.1 0.0 4.9 5 0 0 5 5 4 2 AAA domain AAA_19 PF13245.1 EPY49857.1 - 3.3e-06 26.7 1.4 0.32 10.7 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain cobW PF02492.14 EPY49857.1 - 4.8e-06 26.1 3.2 0.052 12.9 0.1 2.7 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EPY49857.1 - 8.1e-06 25.5 2.7 0.21 11.2 0.1 3.4 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 EPY49857.1 - 8.4e-06 26.5 0.0 0.97 10.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain UPF0079 PF02367.12 EPY49857.1 - 1.2e-05 24.9 5.9 0.11 12.0 0.2 3.4 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EPY49857.1 - 2e-05 24.7 0.1 0.5 10.5 0.0 3.1 3 0 0 3 3 2 2 RNA helicase ABC2_membrane_3 PF12698.2 EPY49857.1 - 5.2e-05 22.4 16.4 5.2e-05 22.4 11.4 3.4 3 2 0 3 3 2 1 ABC-2 family transporter protein AAA_23 PF13476.1 EPY49857.1 - 5.8e-05 23.5 2.0 0.43 10.8 0.1 2.6 1 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPY49857.1 - 7.1e-05 22.7 0.1 3.1 7.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EPY49857.1 - 8e-05 23.1 0.0 8.2 6.9 0.0 3.6 3 0 0 3 3 3 0 Miro-like protein GlgS PF08971.6 EPY49857.1 - 0.00012 21.9 0.0 0.91 9.4 0.0 2.7 2 0 0 2 2 2 2 Glycogen synthesis protein MMR_HSR1 PF01926.18 EPY49857.1 - 0.00012 21.9 0.6 1.5 8.7 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA PF00004.24 EPY49857.1 - 0.00015 21.9 0.0 4.6 7.4 0.0 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EPY49857.1 - 0.00017 21.2 2.4 2 7.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EPY49857.1 - 0.00057 19.4 2.9 3.5 6.9 0.1 4.2 4 0 0 4 4 4 0 AAA-like domain PduV-EutP PF10662.4 EPY49857.1 - 0.0014 18.1 2.7 1.8 8.0 0.1 3.1 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EPY49857.1 - 0.0026 16.8 1.2 2.3 7.1 0.0 2.8 3 0 0 3 3 3 2 Septin AAA_28 PF13521.1 EPY49857.1 - 0.0035 17.3 4.6 1.1 9.1 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EPY49857.1 - 0.0039 16.9 0.0 5.3 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF4243 PF14027.1 EPY49857.1 - 0.0044 16.5 0.0 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4243) AAA_15 PF13175.1 EPY49857.1 - 0.0044 16.1 0.0 2.8 6.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EPY49857.1 - 0.0074 15.5 0.3 0.33 10.1 0.0 3.3 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EPY49857.1 - 0.013 14.9 0.2 20 4.5 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family T2SE PF00437.15 EPY49857.1 - 0.018 13.9 2.1 2.1 7.1 0.1 2.5 1 1 1 2 2 2 0 Type II/IV secretion system protein Thymidylate_kin PF02223.12 EPY49857.1 - 0.02 14.2 0.0 8 5.7 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Dynamin_N PF00350.18 EPY49857.1 - 0.022 14.6 0.1 10 5.9 0.0 2.9 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.4 EPY49857.1 - 0.025 13.5 1.7 4.4 6.1 0.1 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EPY49857.1 - 0.025 14.2 0.0 9 5.9 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase PRK PF00485.13 EPY49857.1 - 0.028 13.9 0.1 8.8 5.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.4 EPY49857.1 - 0.035 12.7 0.7 5.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 EPY49857.1 - 0.036 13.7 1.2 15 5.2 0.1 3.2 4 0 0 4 4 3 0 NTPase DUF3080 PF11279.3 EPY49857.1 - 0.05 12.7 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) AAA_24 PF13479.1 EPY49857.1 - 0.13 11.7 0.7 24 4.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.7 EPY49857.1 - 0.45 9.5 2.0 19 4.1 0.1 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 EPY49857.1 - 0.6 9.5 4.6 11 5.3 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF373 PF04123.8 EPY49857.1 - 1.6 7.6 7.9 5.1 6.0 5.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF373) FeoB_N PF02421.13 EPY49857.1 - 1.9 7.7 4.1 27 4.0 0.2 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF87 PF01935.12 EPY49857.1 - 2.2 8.0 3.7 34 4.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 ABC2_membrane PF01061.19 EPY49858.1 - 3.3e-81 271.4 51.6 1.8e-42 144.8 15.0 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPY49858.1 - 4.5e-49 166.2 0.1 2.6e-18 66.6 0.0 3.4 3 0 0 3 3 3 3 ABC transporter PDR_CDR PF06422.7 EPY49858.1 - 2.8e-33 113.6 12.9 4.4e-27 93.7 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter AAA_25 PF13481.1 EPY49858.1 - 4e-13 49.1 0.1 0.00018 20.9 0.0 3.9 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EPY49858.1 - 1.2e-12 47.3 0.9 0.0002 20.5 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_trans_N PF14510.1 EPY49858.1 - 1.3e-11 44.4 0.0 3.7e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EPY49858.1 - 2.1e-10 40.9 1.6 0.00015 21.7 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EPY49858.1 - 1.6e-07 30.7 4.5 0.05 13.1 0.2 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EPY49858.1 - 2.5e-07 30.0 0.1 0.092 11.8 0.0 3.4 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.1 EPY49858.1 - 2.5e-07 30.8 0.9 0.036 14.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EPY49858.1 - 6.1e-07 29.7 0.1 0.094 13.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 EPY49858.1 - 3e-06 26.7 3.4 0.044 13.2 0.1 2.9 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EPY49858.1 - 4.8e-06 26.2 1.4 0.28 10.9 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_21 PF13304.1 EPY49858.1 - 5e-06 26.6 0.4 0.98 9.3 0.0 4.7 5 0 0 5 5 4 2 AAA domain UPF0079 PF02367.12 EPY49858.1 - 7.1e-06 25.6 5.9 0.1 12.2 0.2 3.3 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EPY49858.1 - 1.2e-05 25.2 1.0 1.4 8.9 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 EPY49858.1 - 1.3e-05 25.2 0.0 0.44 10.7 0.0 3.1 3 0 0 3 3 3 2 RNA helicase AAA_17 PF13207.1 EPY49858.1 - 1.8e-05 25.5 0.2 0.83 10.4 0.0 3.7 4 0 0 4 4 2 2 AAA domain AAA_23 PF13476.1 EPY49858.1 - 2.7e-05 24.5 0.6 0.34 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPY49858.1 - 6.1e-05 22.5 0.6 2.4 7.5 0.0 4.0 4 0 0 4 4 4 1 AAA-like domain NACHT PF05729.7 EPY49858.1 - 0.0001 22.0 7.1 0.19 11.3 0.1 3.6 4 0 0 4 4 3 2 NACHT domain ABC2_membrane_3 PF12698.2 EPY49858.1 - 0.00015 20.9 16.8 0.00015 20.9 11.7 3.6 2 2 0 3 3 3 1 ABC-2 family transporter protein AAA_30 PF13604.1 EPY49858.1 - 0.00023 20.8 2.8 1.8 8.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 EPY49858.1 - 0.00036 21.0 0.1 7.3 7.1 0.0 3.5 3 0 0 3 3 3 0 Miro-like protein AAA_33 PF13671.1 EPY49858.1 - 0.00053 19.8 0.8 2.7 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EPY49858.1 - 0.00069 19.8 0.2 4.2 7.5 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) GlgS PF08971.6 EPY49858.1 - 0.00086 19.1 0.0 0.81 9.6 0.0 2.6 2 0 0 2 2 2 1 Glycogen synthesis protein AAA_28 PF13521.1 EPY49858.1 - 0.00096 19.1 2.7 1 9.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.4 EPY49858.1 - 0.0013 18.2 3.6 1.6 8.1 0.1 3.2 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EPY49858.1 - 0.0016 17.4 1.0 2.1 7.2 0.0 3.0 3 0 0 3 3 3 2 Septin AAA_15 PF13175.1 EPY49858.1 - 0.0032 16.5 0.0 2.5 7.0 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EPY49858.1 - 0.0048 16.6 0.1 4.8 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EPY49858.1 - 0.0071 15.8 0.2 19 4.6 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family T2SE PF00437.15 EPY49858.1 - 0.0088 14.9 0.5 3.6 6.4 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein SMC_N PF02463.14 EPY49858.1 - 0.013 14.7 0.6 0.52 9.5 0.0 3.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 EPY49858.1 - 0.017 14.9 0.1 9.3 6.0 0.0 3.1 3 0 0 3 3 2 0 Dynamin family Arch_ATPase PF01637.13 EPY49858.1 - 0.02 14.6 0.0 6.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase PRK PF00485.13 EPY49858.1 - 0.029 13.9 0.1 8.8 5.8 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 EPY49858.1 - 0.035 13.0 1.4 4.8 6.0 0.0 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EPY49858.1 - 0.049 13.3 1.6 13 5.4 0.1 3.0 4 0 0 4 4 3 0 NTPase ABC_ATPase PF09818.4 EPY49858.1 - 0.06 11.9 1.7 5.4 5.4 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.1 EPY49858.1 - 0.099 12.2 0.6 22 4.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF3080 PF11279.3 EPY49858.1 - 0.17 11.0 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Thymidylate_kin PF02223.12 EPY49858.1 - 0.18 11.1 0.1 8.7 5.6 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase FeoB_N PF02421.13 EPY49858.1 - 0.26 10.5 3.5 22 4.2 0.1 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B Pox_A32 PF04665.7 EPY49858.1 - 0.27 10.4 0.8 25 4.0 0.1 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein RuvB_N PF05496.7 EPY49858.1 - 0.37 9.8 1.9 17 4.3 0.1 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 EPY49858.1 - 1.2 8.8 2.3 36 4.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EPY49858.1 - 1.7 8.4 3.7 31 4.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 SRP54 PF00448.17 EPY49858.1 - 2.5 7.4 6.7 14 5.0 0.5 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Vps5 PF09325.5 EPY49859.1 - 4.1e-63 212.7 13.1 5.9e-63 212.2 9.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EPY49859.1 - 3e-24 85.0 0.5 6.4e-24 83.9 0.1 1.8 2 0 0 2 2 2 1 PX domain FGGY_C PF02782.11 EPY49860.1 - 3.1e-28 98.7 0.0 6.6e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPY49860.1 - 9.1e-19 67.7 0.0 1.8e-16 60.2 0.0 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF1546 PF07571.8 EPY49861.1 - 2e-35 120.7 0.0 4.6e-35 119.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EPY49861.1 - 2.3e-28 97.9 0.3 4.9e-28 96.8 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EPY49861.1 - 0.0059 16.7 0.3 0.015 15.3 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY49861.1 - 0.016 15.2 0.2 0.064 13.3 0.1 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HEAT_EZ PF13513.1 EPY49861.1 - 0.15 12.6 4.0 3.3 8.3 0.0 3.6 4 0 0 4 4 4 0 HEAT-like repeat DUF2414 PF10309.4 EPY49863.1 - 1.3e-21 75.9 0.0 2e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF2414 PF10309.4 EPY49864.1 - 2e-21 75.4 0.0 3e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Ribosomal_L2_C PF03947.13 EPY49865.1 - 4.5e-49 165.5 0.1 7.4e-49 164.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPY49865.1 - 5.9e-29 99.8 0.2 2.7e-28 97.7 0.1 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Toxin_39 PF15500.1 EPY49865.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin TPR_11 PF13414.1 EPY49866.1 - 2e-22 78.5 28.5 1.7e-05 24.3 0.5 8.9 5 2 3 9 9 9 5 TPR repeat TPR_8 PF13181.1 EPY49866.1 - 5.7e-15 53.8 15.3 5.1e-05 22.7 0.2 8.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPY49866.1 - 3e-14 51.6 29.1 0.0011 18.6 0.1 11.2 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY49866.1 - 4.6e-12 44.9 24.6 8.1e-05 22.0 0.3 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPY49866.1 - 3.4e-10 39.6 14.7 0.05 14.2 0.0 9.0 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPY49866.1 - 1.5e-09 37.6 28.4 0.00055 19.8 0.5 8.6 8 1 2 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EPY49866.1 - 1.8e-09 37.8 15.4 0.013 15.8 0.1 8.7 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPY49866.1 - 5.6e-09 36.4 15.1 0.025 15.2 0.0 7.2 7 1 2 9 9 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EPY49866.1 - 1.5e-06 28.2 3.8 0.028 14.8 0.1 5.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPY49866.1 - 0.00095 19.0 13.5 0.19 11.7 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPY49866.1 - 0.0046 16.0 13.2 0.0086 15.1 0.3 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPY49866.1 - 0.015 15.1 12.8 0.041 13.7 0.5 5.8 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPY49866.1 - 0.27 11.1 14.1 0.62 10.0 0.1 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPY49866.1 - 0.59 10.4 23.3 29 5.1 0.3 9.3 11 0 0 11 11 10 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 EPY49867.1 - 6.6e-17 60.7 0.2 1e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPY49867.1 - 3.2e-11 43.2 0.1 6.1e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Acetyltransf_1 PF00583.19 EPY49868.1 - 3.1e-11 43.1 0.0 4.2e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY49868.1 - 0.00024 21.1 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY49868.1 - 0.00039 20.1 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPY49868.1 - 0.0028 17.7 0.0 0.0038 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY49868.1 - 0.0044 16.8 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EPY49869.1 - 2e-75 253.3 0.0 2.3e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49869.1 - 7.4e-36 123.5 0.0 9.5e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY49869.1 - 0.00068 19.4 0.0 0.13 12.0 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY49869.1 - 0.018 13.9 0.0 0.06 12.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Glucosamine_iso PF01182.15 EPY49870.1 - 1.9e-61 207.2 0.0 2.3e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CBFD_NFYB_HMF PF00808.18 EPY49871.1 - 2e-13 50.1 0.2 2.3e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPY49871.1 - 1.6e-07 31.3 0.0 2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.8 EPY49871.1 - 0.0064 16.2 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TFIID-18kDa PF02269.11 EPY49871.1 - 0.011 15.4 0.3 0.017 14.9 0.2 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 EPY49871.1 - 0.017 15.4 0.7 0.022 15.0 0.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EPY49871.1 - 0.05 13.7 0.1 0.067 13.3 0.1 1.1 1 0 0 1 1 1 0 Kinetochore component CENP-S RNB PF00773.14 EPY49872.1 - 1.4e-48 165.8 0.0 2.1e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain WD40 PF00400.27 EPY49873.1 - 4.7e-19 67.4 9.0 4.6e-06 26.3 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPY49873.1 - 0.00014 20.7 2.1 0.066 11.9 0.0 3.0 1 1 2 3 3 3 2 Nup133 N terminal like BBS2_Mid PF14783.1 EPY49873.1 - 0.00017 21.2 0.0 0.0026 17.5 0.0 2.6 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.9 EPY49873.1 - 0.00053 18.9 0.2 0.00083 18.2 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region CDC45 PF02724.9 EPY49873.1 - 0.032 12.2 2.7 0.042 11.8 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PQQ PF01011.16 EPY49873.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat RRM_1 PF00076.17 EPY49874.1 - 2.2e-14 52.8 0.0 3.3e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49874.1 - 2e-05 24.4 0.0 7.8e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49874.1 - 0.06 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PseudoU_synth_1 PF01416.15 EPY49875.1 - 4.4e-20 72.0 0.3 3.3e-08 33.8 0.0 3.3 3 0 0 3 3 3 2 tRNA pseudouridine synthase RNase_P_pop3 PF08228.6 EPY49876.1 - 3.1e-20 72.5 0.2 3.7e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 RNase P subunit Pop3 Rotamase PF00639.16 EPY49878.1 - 1.3e-22 80.2 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EPY49878.1 - 2.4e-19 69.7 0.0 2.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EPY49878.1 - 5e-07 30.3 0.0 6.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EPY49878.1 - 5.4e-07 29.3 0.6 1.6e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 WW domain Neurochondrin PF05536.6 EPY49879.1 - 5.7e-90 302.1 2.4 7.4e-90 301.8 1.7 1.1 1 0 0 1 1 1 1 Neurochondrin ATG16 PF08614.6 EPY49880.1 - 0.0033 17.2 0.8 0.0037 17.1 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 EPY49880.1 - 0.017 15.0 5.9 0.022 14.6 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 EPY49880.1 - 0.072 11.7 1.3 0.085 11.5 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF155 PF02582.9 EPY49881.1 - 1.2e-52 178.3 0.9 1.7e-52 177.8 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Rpr2 PF04032.11 EPY49882.1 - 3.2e-13 49.3 0.0 7.1e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_5 PF13719.1 EPY49882.1 - 0.048 13.2 0.8 4.7 6.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-trcl PF13451.1 EPY49882.1 - 0.065 12.8 2.7 5.8 6.6 0.1 2.6 2 0 0 2 2 2 0 Probable zinc-binding domain zinc_ribbon_4 PF13717.1 EPY49882.1 - 0.083 12.5 0.4 4.9 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Mut7-C PF01927.11 EPY49882.1 - 0.11 12.5 0.1 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Mut7-C RNAse domain Ribosomal_L18e PF00828.14 EPY49883.1 - 7.4e-34 116.9 0.1 8.8e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 SMC_N PF02463.14 EPY49884.1 - 2.3e-28 98.9 0.0 1.1e-27 96.6 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPY49884.1 - 6.6e-17 62.5 1.8 6.6e-17 62.5 1.2 5.4 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 EPY49884.1 - 0.00034 20.0 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EPY49884.1 - 0.0038 17.2 5.2 0.02 14.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain Peptidase_C50 PF03568.12 EPY49886.1 - 5.2e-123 410.5 0.0 5.2e-123 410.5 0.0 2.2 3 0 0 3 3 3 1 Peptidase family C50 TPR_12 PF13424.1 EPY49886.1 - 0.44 10.5 6.3 3.1 7.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EPY49887.1 - 9.7e-27 94.3 0.0 1.2e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY49887.1 - 2.6e-19 69.4 0.0 7e-19 68.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPY49887.1 - 2.5e-16 59.2 0.1 6.5e-16 57.9 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EPY49887.1 - 1.6e-11 44.2 1.4 3.6e-09 36.5 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPY49887.1 - 0.00043 19.8 0.1 1.6 8.0 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 EPY49887.1 - 0.018 13.5 0.1 0.022 13.2 0.1 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_3 PF07859.8 EPY49887.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EPY49887.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Velvet PF11754.3 EPY49887.1 - 0.044 13.3 0.2 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Velvet factor DLH PF01738.13 EPY49887.1 - 0.13 11.4 0.1 4.1 6.6 0.1 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family WD40 PF00400.27 EPY49888.1 - 4.8e-60 197.4 14.1 6.7e-11 41.6 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EPY49888.1 - 3e-44 150.5 2.7 4.7e-44 149.9 1.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EPY49888.1 - 6.7e-06 25.6 0.1 2.4e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 LisH Nup160 PF11715.3 EPY49888.1 - 0.0068 14.6 1.6 0.79 7.7 0.0 3.1 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Exo_endo_phos PF03372.18 EPY49889.1 - 6e-22 78.7 0.1 1.2e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EPY49889.1 - 9e-17 60.2 1.2 5.4e-09 35.4 0.4 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPY49889.1 - 1.2e-09 37.7 13.2 3.9e-06 26.5 1.0 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EPY49889.1 - 4.5e-08 32.0 2.9 0.31 11.2 0.1 5.6 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EPY49889.1 - 0.00047 19.8 0.4 1.3 9.5 0.1 4.4 4 0 0 4 4 4 1 Leucine rich repeat Sec23_trunk PF04811.10 EPY49891.1 - 1.1e-80 270.5 0.0 1.7e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EPY49891.1 - 7.1e-32 109.8 0.1 1.3e-31 108.9 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EPY49891.1 - 2.7e-31 107.0 0.1 7.3e-31 105.6 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EPY49891.1 - 1.7e-15 56.2 5.4 3.1e-15 55.4 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPY49891.1 - 8.1e-12 44.6 0.0 2.9e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Metallophos PF00149.23 EPY49893.1 - 1.1e-44 152.2 0.4 1.3e-44 152.0 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L11_N PF03946.9 EPY49895.1 - 6.6e-17 60.7 0.2 1e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPY49895.1 - 3.2e-11 43.2 0.1 6.1e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SAP PF02037.22 EPY49896.1 - 1.2e-10 40.6 0.1 7.4e-10 38.0 0.0 2.1 2 0 0 2 2 2 1 SAP domain Hex_IIIa PF02455.11 EPY49896.1 - 5.9 5.4 11.0 7.9 5.0 7.6 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Bac_rhodopsin PF01036.13 EPY49897.1 - 3.9e-29 101.5 28.0 5.4e-29 101.0 19.4 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein GST_N_3 PF13417.1 EPY49898.1 - 5.7e-15 55.2 0.0 9.8e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPY49898.1 - 2.5e-11 43.4 0.0 3.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPY49898.1 - 4.8e-09 36.0 0.0 9.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPY49898.1 - 8.6e-09 35.4 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPY49898.1 - 2.6e-08 34.2 0.0 4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPY49898.1 - 0.00098 18.9 0.0 0.0037 17.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1972 PF09314.6 EPY49898.1 - 0.041 13.3 0.1 0.064 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) MS_channel PF00924.13 EPY49899.1 - 4.6e-19 68.5 1.4 8.5e-19 67.6 1.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Pmp3 PF01679.12 EPY49900.1 - 6.1e-16 57.8 8.1 8e-16 57.4 5.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator IncA PF04156.9 EPY49900.1 - 0.035 13.6 0.1 0.039 13.5 0.1 1.0 1 0 0 1 1 1 0 IncA protein DUF4585 PF15232.1 EPY49900.1 - 0.19 11.5 1.9 0.25 11.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Ribosomal_L1 PF00687.16 EPY49901.1 - 5.4e-50 169.7 1.1 6.3e-50 169.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family S1 PF00575.18 EPY49902.1 - 7e-83 272.7 33.9 3.3e-14 52.7 0.6 12.5 12 0 0 12 12 12 11 S1 RNA binding domain Suf PF05843.9 EPY49902.1 - 2.9e-10 40.3 0.2 1.5e-07 31.4 0.1 4.5 2 2 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EPY49902.1 - 8.8e-10 38.7 0.0 0.00063 20.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPY49902.1 - 2.9e-08 33.6 0.1 0.15 12.7 0.0 4.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY49902.1 - 8.4e-07 29.5 0.0 0.0043 17.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 EPY49902.1 - 0.0018 17.4 0.1 0.17 10.9 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPY49902.1 - 0.0095 16.3 0.2 1.5 9.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat UDG PF03167.14 EPY49903.1 - 1.9e-24 85.8 0.1 2.9e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sec2p PF06428.6 EPY49904.1 - 5.9e-08 32.4 12.2 5.9e-08 32.4 8.5 1.9 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Alpha-2-MRAP_C PF06401.6 EPY49904.1 - 0.016 15.1 10.6 0.018 14.8 7.4 1.0 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF3496 PF12001.3 EPY49904.1 - 0.14 12.3 11.0 0.035 14.3 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) DUF733 PF05306.6 EPY49904.1 - 0.21 11.9 16.7 0.38 11.0 2.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF733) Mu-like_Pro PF10123.4 EPY49904.1 - 0.23 10.8 4.9 0.27 10.6 3.4 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein DUF935 PF06074.7 EPY49904.1 - 0.31 9.7 6.5 0.35 9.5 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Atg14 PF10186.4 EPY49904.1 - 0.36 9.7 14.7 0.43 9.4 10.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FTCD_C PF04961.7 EPY49904.1 - 0.49 9.7 5.8 0.7 9.2 4.0 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase APG6 PF04111.7 EPY49904.1 - 0.52 9.3 14.3 0.61 9.0 9.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EPY49904.1 - 0.73 9.3 14.6 0.94 9.0 10.1 1.2 1 0 0 1 1 1 0 IncA protein Metal_resist PF13801.1 EPY49904.1 - 0.98 9.4 7.1 1.3 9.0 5.0 1.1 1 0 0 1 1 1 0 Heavy-metal resistance SPATIAL PF15256.1 EPY49904.1 - 1.4 8.9 7.3 1.7 8.7 5.1 1.1 1 0 0 1 1 1 0 SPATIAL DivIVA PF05103.8 EPY49904.1 - 1.4 9.0 15.6 1.6 8.8 10.5 1.3 1 1 0 1 1 1 0 DivIVA protein DUF4407 PF14362.1 EPY49904.1 - 1.5 7.7 6.2 1.9 7.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1266 PF06889.6 EPY49904.1 - 1.6 8.5 4.9 2.1 8.1 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) DUF342 PF03961.8 EPY49904.1 - 2.8 6.2 10.4 3.9 5.7 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EPY49904.1 - 3.2 7.5 7.0 4.3 7.1 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) KfrA_N PF11740.3 EPY49904.1 - 3.5 8.0 13.3 11 6.5 8.9 1.8 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF1640 PF07798.6 EPY49904.1 - 3.6 7.5 14.3 5.2 7.0 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GvpL_GvpF PF06386.6 EPY49904.1 - 3.8 7.0 10.1 3.2 7.2 6.1 1.5 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF SPX PF03105.14 EPY49904.1 - 5 6.8 12.6 6.2 6.5 8.7 1.1 1 0 0 1 1 1 0 SPX domain V_ATPase_I PF01496.14 EPY49904.1 - 5.6 4.6 10.2 6.3 4.5 7.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Orbi_VP5 PF00901.12 EPY49904.1 - 6.7 4.7 13.3 8.1 4.5 9.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF4404 PF14357.1 EPY49904.1 - 8.1 6.9 13.0 2.5 8.5 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) OmpH PF03938.9 EPY49904.1 - 9.4 6.1 17.1 13 5.6 11.9 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DNA_ligase_A_M PF01068.16 EPY49905.1 - 4.9e-51 172.9 0.2 1.2e-50 171.7 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPY49905.1 - 4.3e-40 137.4 0.0 1e-39 136.1 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPY49905.1 - 7e-13 48.8 0.0 1.7e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EPY49905.1 - 1.1e-05 25.4 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EPY49905.1 - 0.00025 20.7 3.8 0.00057 19.6 0.5 2.8 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain NOSIC PF08060.8 EPY49905.1 - 0.046 13.5 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 NOSIC (NUC001) domain DNA_ligase_A_M PF01068.16 EPY49906.1 - 7.6e-51 172.3 0.2 1.7e-50 171.2 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPY49906.1 - 5.8e-40 136.9 0.0 1.5e-39 135.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPY49906.1 - 9.3e-13 48.4 0.0 2.3e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EPY49906.1 - 6.9e-11 42.1 0.0 4.1e-05 23.6 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EPY49906.1 - 0.00047 19.9 4.0 0.00095 18.9 0.5 2.8 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.2 EPY49906.1 - 0.032 14.0 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 twin BRCT domain NOSIC PF08060.8 EPY49906.1 - 0.051 13.3 0.0 0.22 11.3 0.0 2.1 1 0 0 1 1 1 0 NOSIC (NUC001) domain Pet127 PF08634.5 EPY49907.1 - 9.1e-82 274.2 3.0 6.2e-60 202.6 0.1 2.5 2 1 1 3 3 3 2 Mitochondrial protein Pet127 Frataxin_Cyay PF01491.11 EPY49908.1 - 2.5e-34 117.3 0.0 3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain GST_C PF00043.20 EPY49909.1 - 7.8e-11 41.8 0.0 2e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPY49909.1 - 2e-08 33.9 0.0 4.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY49909.1 - 2.5e-05 24.6 0.0 5.1e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPY49909.1 - 5.1e-05 23.3 0.0 0.00013 22.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPY49909.1 - 0.00024 21.2 0.0 0.00052 20.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Sec15 PF04091.7 EPY49910.1 - 3.3e-70 236.8 0.6 3.3e-70 236.8 0.5 2.3 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 EPY49910.1 - 0.00066 19.3 4.3 0.0022 17.6 3.0 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Baculo_PEP_C PF04513.7 EPY49910.1 - 0.92 9.3 9.8 3.4 7.5 3.6 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EPY49910.1 - 4.9 6.6 12.0 11 5.5 8.3 1.6 1 0 0 1 1 1 0 IncA protein DUF410 PF04190.8 EPY49911.1 - 1.2e-67 228.2 0.0 1.4e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Chorion_2 PF03964.10 EPY49911.1 - 0.036 14.5 0.0 0.058 13.9 0.0 1.3 1 0 0 1 1 1 0 Chorion family 2 P5-ATPase PF12409.3 EPY49912.1 - 4.1e-33 113.7 0.0 4.1e-33 113.7 0.0 3.6 4 0 0 4 4 4 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 EPY49912.1 - 6e-30 103.9 0.1 6e-30 103.9 0.1 2.0 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 EPY49912.1 - 2.2e-23 83.4 0.0 3.7e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY49912.1 - 7.2e-12 46.1 0.0 4.9e-08 33.6 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY49912.1 - 7.9e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPY49912.1 - 0.00013 21.3 0.0 0.00034 20.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus RnaseA PF00074.15 EPY49912.1 - 0.13 12.5 0.3 0.25 11.6 0.2 1.4 1 0 0 1 1 1 0 Pancreatic ribonuclease Hydrolase_3 PF08282.7 EPY49912.1 - 0.15 11.6 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EPY49913.1 - 8.5e-39 130.0 7.9 2.1e-09 36.8 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPY49913.1 - 1.7e-31 107.9 0.6 3.2e-31 107.0 0.4 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Abhydro_lipase PF04083.11 EPY49914.1 - 3.2e-21 74.4 0.0 6.2e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EPY49914.1 - 1.5e-20 73.7 0.5 2.2e-20 73.2 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPY49914.1 - 4.7e-10 39.7 0.0 9.5e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY49914.1 - 3.8e-07 29.9 0.0 1.8e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPY49914.1 - 0.00018 21.0 0.6 0.23 10.8 0.0 3.0 3 0 0 3 3 3 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EPY49914.1 - 0.12 11.7 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TMA7 PF09072.5 EPY49914.1 - 3.2 8.2 6.0 6.8 7.2 4.2 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 TFIIE_beta PF02186.10 EPY49915.1 - 1.9e-25 88.6 0.9 3.7e-25 87.7 0.6 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain Utp21 PF04192.7 EPY49916.1 - 2e-69 233.3 1.7 2.8e-69 232.8 1.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EPY49916.1 - 7e-18 63.7 14.7 4.2e-08 32.7 0.3 9.1 10 0 0 10 10 10 3 WD domain, G-beta repeat Nup160 PF11715.3 EPY49916.1 - 1.7e-07 29.7 1.2 0.014 13.5 0.0 3.6 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EPY49916.1 - 3.5e-05 22.2 0.1 9.2e-05 20.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EPY49916.1 - 0.045 12.4 7.6 0.16 10.6 0.3 3.4 2 2 2 4 4 4 0 Nup133 N terminal like Hira PF07569.6 EPY49916.1 - 0.046 12.9 2.4 13 4.9 0.0 4.5 4 2 0 5 5 5 0 TUP1-like enhancer of split ALS_ss_C PF10369.4 EPY49916.1 - 0.047 13.4 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 Small subunit of acetolactate synthase His_Phos_2 PF00328.17 EPY49917.1 - 1.2e-117 393.1 2.4 1.5e-117 392.8 1.7 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EPY49917.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain tRNA-synt_1b PF00579.20 EPY49918.1 - 6.5e-69 232.2 0.0 9e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) YqzE PF14038.1 EPY49918.1 - 1.6 8.5 5.2 3.9 7.2 3.6 1.6 1 0 0 1 1 1 0 YqzE-like protein CHCH PF06747.8 EPY49919.1 - 1.6e-09 37.3 3.3 2.2e-09 36.9 2.3 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EPY49919.1 - 0.013 15.5 3.6 0.021 14.8 2.5 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EPY49919.1 - 0.029 14.1 1.1 10 5.9 0.1 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EPY49919.1 - 0.37 10.6 4.0 3.2 7.6 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EPY49919.1 - 0.53 10.3 3.3 2.2 8.3 1.4 2.3 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) Amidohydro_1 PF01979.15 EPY49920.1 - 3.2e-44 151.9 0.0 4.1e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPY49920.1 - 1.3e-07 32.0 0.1 5.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EPY49920.1 - 1.3e-07 31.2 1.9 1.2e-05 24.7 0.0 2.5 2 1 1 3 3 3 2 Amidohydrolase family A_deaminase PF00962.17 EPY49920.1 - 0.0056 15.6 0.0 0.013 14.4 0.0 1.5 2 0 0 2 2 2 1 Adenosine/AMP deaminase Amidohydro_5 PF13594.1 EPY49920.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase Nsp1_C PF05064.8 EPY49921.1 - 0.0006 19.4 3.9 0.0062 16.1 0.8 2.5 2 0 0 2 2 2 1 Nsp1-like C-terminal region Uds1 PF15456.1 EPY49921.1 - 0.0029 17.5 7.3 0.01 15.8 0.2 2.7 2 1 1 3 3 3 1 Up-regulated During Septation Seryl_tRNA_N PF02403.17 EPY49921.1 - 0.022 14.7 3.4 0.089 12.8 2.4 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phi-29_GP4 PF05464.6 EPY49921.1 - 0.057 13.3 0.3 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) DUF3408 PF11888.3 EPY49921.1 - 0.069 13.0 0.3 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Imm31 PF15595.1 EPY49921.1 - 0.085 12.6 0.8 0.24 11.1 0.2 2.0 2 1 0 2 2 2 0 Immunity protein 31 PilJ PF13675.1 EPY49921.1 - 0.089 13.1 0.5 0.22 11.8 0.1 1.9 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF837 PF05769.6 EPY49921.1 - 0.25 10.8 0.1 0.25 10.8 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF837) DUF4164 PF13747.1 EPY49921.1 - 1 9.5 10.1 1.3 9.2 0.7 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 EPY49921.1 - 1 9.6 3.8 2.1 8.6 1.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2408 PF10303.4 EPY49921.1 - 2.3 8.3 8.0 3.3 7.8 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Nup54 PF13874.1 EPY49921.1 - 2.9 7.5 9.0 2.9 7.5 1.1 2.8 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 PHP PF02811.14 EPY49922.1 - 1.8e-16 60.4 0.1 2.7e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 PHP domain zf-CCHC PF00098.18 EPY49923.1 - 1.1e-10 40.9 10.0 9.9e-06 25.2 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EPY49923.1 - 1.1e-05 24.9 0.1 1.9e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EPY49923.1 - 2.1e-05 24.0 0.2 4.4e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EPY49923.1 - 3.6e-05 23.3 5.5 0.0072 16.0 0.5 3.0 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EPY49923.1 - 0.002 17.7 6.0 0.27 10.9 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EPY49923.1 - 0.0058 16.2 11.0 0.081 12.6 0.6 3.2 3 0 0 3 3 3 2 Zinc knuckle FATC PF02260.15 EPY49923.1 - 0.034 13.5 0.7 0.066 12.6 0.5 1.5 1 0 0 1 1 1 0 FATC domain FUR PF01475.14 EPY49923.1 - 0.13 12.1 0.4 5.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Ferric uptake regulator family Zn_Tnp_IS1595 PF12760.2 EPY49923.1 - 7.6 6.4 6.7 21 5.0 0.4 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain XPG_I_2 PF12813.2 EPY49924.1 - 8.4e-48 163.0 0.0 1.1e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EPY49924.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region Ribosomal_L7Ae PF01248.21 EPY49925.1 - 1.9e-28 97.8 0.9 2.8e-28 97.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Snf7 PF03357.16 EPY49925.1 - 0.23 10.8 3.9 0.91 8.8 1.8 2.0 2 0 0 2 2 2 0 Snf7 Acetyltransf_7 PF13508.1 EPY49926.1 - 2.6e-14 53.1 0.1 3.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPY49926.1 - 1.9e-08 34.1 0.2 2.7e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPY49926.1 - 6.2e-06 26.3 0.0 7.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EPY49926.1 - 0.0011 19.5 0.2 0.031 14.8 0.1 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY49926.1 - 0.0071 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EPY49926.1 - 0.054 13.3 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EPY49926.1 - 0.11 12.4 0.2 0.25 11.2 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EPY49926.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Arm PF00514.18 EPY49927.1 - 8.4e-90 291.8 16.9 2.4e-13 49.3 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 EPY49927.1 - 2.3e-25 88.5 5.9 3.6e-25 87.9 4.1 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 EPY49927.1 - 5.5e-22 77.8 0.0 3.5e-07 30.3 0.0 5.5 2 1 3 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 EPY49927.1 - 3.1e-18 65.6 1.7 1.5e-07 31.7 0.0 6.0 7 2 0 7 7 7 3 HEAT-like repeat HEAT PF02985.17 EPY49927.1 - 4.9e-15 54.1 0.0 1.9e-05 24.3 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.8 EPY49927.1 - 9.2e-08 31.5 0.0 0.11 11.5 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Proteasom_PSMB PF10508.4 EPY49927.1 - 1.7e-05 23.2 0.1 0.12 10.6 0.0 3.2 2 1 1 3 3 3 3 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 EPY49927.1 - 3.5e-05 23.6 0.0 0.68 9.8 0.0 4.7 3 3 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.1 EPY49927.1 - 0.0013 18.6 4.6 1.8 8.5 0.1 4.6 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EPY49927.1 - 0.016 15.5 0.1 1.5 9.4 0.0 3.9 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat DUF3552 PF12072.3 EPY49927.1 - 0.058 12.6 6.6 0.1 11.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SEN1_N PF12726.2 EPY49927.1 - 0.07 11.1 0.0 8.5 4.2 0.0 3.1 3 0 0 3 3 3 0 SEN1 N terminal Neurokinin_B PF03823.9 EPY49927.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Neurokinin B BIR PF00653.16 EPY49928.1 - 1.7e-39 134.0 6.5 9.6e-21 73.9 0.2 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain C2 PF00168.25 EPY49929.1 - 5.7e-34 115.8 1.5 5.8e-14 51.6 0.0 5.1 5 0 0 5 5 5 4 C2 domain DUF2404 PF10296.4 EPY49929.1 - 0.017 15.2 0.2 0.16 12.1 0.0 2.6 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) Ribosomal_L35Ae PF01247.13 EPY49930.1 - 2.1e-39 133.1 0.4 2.3e-39 133.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EPY49930.1 - 0.00017 21.4 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain GTP_EFTU PF00009.22 EPY49931.1 - 1.2e-61 207.4 0.1 1.7e-61 206.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPY49931.1 - 1.5e-33 114.9 0.0 3.9e-33 113.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPY49931.1 - 6.4e-20 70.8 0.0 1.6e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EPY49931.1 - 1.5e-13 50.3 0.0 3.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EPY49931.1 - 7.4e-12 45.2 1.5 1.5e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPY49931.1 - 5.9e-05 23.0 0.1 0.00012 21.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAP_assoc PF03828.14 EPY49931.1 - 0.16 11.9 0.2 0.48 10.4 0.1 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase C2 PF00168.25 EPY49932.1 - 5.8e-26 90.1 0.3 2.3e-17 62.5 0.0 2.8 2 0 0 2 2 2 2 C2 domain Tyr-DNA_phospho PF06087.7 EPY49933.1 - 1.8e-100 336.6 3.3 3e-64 217.2 0.6 2.6 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EPY49933.1 - 0.0089 15.7 0.1 0.31 10.7 0.0 2.5 2 0 0 2 2 2 1 PLD-like domain DUF4448 PF14610.1 EPY49934.1 - 1.1e-28 99.9 0.1 2.6e-28 98.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EPY49934.1 - 0.063 13.7 0.5 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med31 PF05669.7 EPY49935.1 - 2.4e-38 130.0 5.0 2.9e-38 129.7 3.5 1.0 1 0 0 1 1 1 1 SOH1 Oxidored-like PF09791.4 EPY49936.1 - 1.1e-22 79.2 1.8 1.7e-22 78.6 1.2 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DnaJ PF00226.26 EPY49937.1 - 8.8e-22 76.6 1.7 2.2e-21 75.3 1.2 1.8 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EPY49937.1 - 0.00085 18.9 0.1 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY49937.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49937.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Chordopox_A13L PF05961.6 EPY49937.1 - 0.13 12.1 0.1 0.47 10.4 0.1 2.0 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DEAD PF00270.24 EPY49938.1 - 2.8e-44 150.5 0.0 1.5e-43 148.2 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY49938.1 - 2.8e-25 87.9 0.0 6.7e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPY49938.1 - 0.0023 16.7 0.0 0.004 15.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC4 PF02732.10 EPY49939.1 - 1.3e-24 86.5 0.2 6.1e-24 84.4 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain Yippee-Mis18 PF03226.9 EPY49940.1 - 7.5e-21 73.9 1.0 1.1e-20 73.4 0.7 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Glyco_hydro_76 PF03663.9 EPY49941.1 - 1.3e-140 469.0 16.7 1.7e-140 468.6 11.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPY49941.1 - 0.014 14.4 7.4 0.09 11.7 0.1 3.1 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 NAD_binding_1 PF00175.16 EPY49942.1 - 7.9e-30 103.6 0.0 1.3e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPY49942.1 - 2.3e-28 98.2 0.0 3.6e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EPY49942.1 - 4.6e-05 23.3 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EPY49942.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Mob1_phocein PF03637.12 EPY49943.1 - 2e-70 235.9 1.4 2.4e-70 235.7 1.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_L36e PF01158.13 EPY49944.1 - 8.7e-40 134.6 3.7 9.4e-40 134.5 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.1 EPY49944.1 - 0.055 13.2 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal LemA PF04011.7 EPY49944.1 - 0.069 12.2 0.1 0.073 12.1 0.1 1.1 1 0 0 1 1 1 0 LemA family SURF4 PF02077.10 EPY49945.1 - 1e-107 359.5 6.7 1.2e-107 359.2 4.6 1.0 1 0 0 1 1 1 1 SURF4 family YhhN PF07947.9 EPY49945.1 - 0.0038 16.6 4.7 0.0038 16.6 3.3 2.1 1 1 1 2 2 2 1 YhhN-like protein DNMT1-RFD PF12047.3 EPY49946.1 - 7e-14 51.7 0.2 1.2e-13 50.9 0.2 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain IPK PF03770.11 EPY49947.1 - 2.3e-52 177.4 0.0 4.4e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase Sec8_exocyst PF04048.9 EPY49948.1 - 1.5e-34 118.6 1.2 5.1e-34 116.9 0.1 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Zw10 PF06248.8 EPY49948.1 - 9.4e-06 24.0 0.5 2.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 BRE1 PF08647.6 EPY49949.1 - 5.1e-12 45.6 10.0 5.1e-12 45.6 6.9 5.5 6 0 0 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EPY49949.1 - 6e-08 32.5 10.1 1.2e-07 31.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY49949.1 - 1.7e-06 27.5 9.5 3.8e-06 26.4 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY49949.1 - 2.1e-05 24.0 9.7 4.1e-05 23.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY49949.1 - 0.00057 19.6 10.0 0.00057 19.6 6.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPY49949.1 - 0.00077 19.1 12.0 0.0018 17.9 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPY49949.1 - 0.00085 19.3 8.7 0.0018 18.3 4.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPY49949.1 - 0.053 13.2 6.4 0.21 11.3 4.4 2.2 1 0 0 1 1 1 0 RING-type zinc-finger DUF904 PF06005.7 EPY49949.1 - 0.08 13.2 0.2 0.08 13.2 0.1 7.1 4 1 1 5 5 4 0 Protein of unknown function (DUF904) zf-C3HC4_4 PF15227.1 EPY49949.1 - 0.34 10.8 12.2 0.17 11.7 5.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EPY49949.1 - 0.38 10.6 5.3 0.46 10.3 2.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPY49949.1 - 8.1 6.1 12.4 0.27 10.8 3.9 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FlaC_arch PF05377.6 EPY49949.1 - 9.7 6.1 16.2 1.6 8.6 0.4 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF3987 PF13148.1 EPY49950.1 - 4.6 5.7 9.2 6.7 5.1 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Es2 PF09751.4 EPY49951.1 - 1e-31 110.8 19.2 2e-18 67.0 4.6 3.2 1 1 2 3 3 3 3 Nuclear protein Es2 Ribosomal_L22 PF00237.14 EPY49952.1 - 1.1e-33 115.2 0.1 1.8e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CBF_beta PF02312.12 EPY49952.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit CASP_C PF08172.7 EPY49953.1 - 5e-44 150.1 15.1 5e-44 150.1 10.4 5.8 2 1 2 4 4 4 1 CASP C terminal KLRAQ PF10205.4 EPY49953.1 - 0.00038 20.4 7.9 0.00038 20.4 5.5 6.4 4 2 3 7 7 7 1 Predicted coiled-coil domain-containing protein CNH PF00780.17 EPY49954.1 - 1.8e-10 40.7 0.1 3.4e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 EPY49954.1 - 0.00042 20.3 4.0 0.0019 18.2 1.2 3.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EPY49954.1 - 0.014 15.6 0.0 0.045 13.9 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_12 PF13424.1 EPY49954.1 - 0.049 13.5 0.4 9.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPY49954.1 - 0.056 13.2 0.4 5.6 6.9 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat NAP PF00956.13 EPY49955.1 - 1.6e-80 269.7 7.7 1.6e-80 269.7 5.3 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) 2-Hacid_dh_C PF02826.14 EPY49956.1 - 9.8e-50 168.1 0.0 1.5e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPY49956.1 - 1.4e-38 131.3 0.0 1.9e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPY49956.1 - 0.0001 22.1 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EPY49956.1 - 0.0016 18.3 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HIT PF01230.18 EPY49957.1 - 7.5e-20 71.2 0.3 3.8e-18 65.8 0.2 2.3 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPY49957.1 - 0.0002 21.5 0.2 0.0044 17.2 0.2 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2415 PF10313.4 EPY49958.1 - 9e-12 44.4 0.0 6e-11 41.8 0.0 2.4 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EPY49958.1 - 2.2 8.3 10.0 0.56 10.1 0.1 4.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Ubie_methyltran PF01209.13 EPY49959.1 - 1e-84 283.3 0.0 1.3e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPY49959.1 - 8.5e-16 57.8 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY49959.1 - 1.6e-12 47.7 0.0 3.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY49959.1 - 1.3e-11 44.8 0.0 2.5e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY49959.1 - 2.4e-10 40.9 0.0 4.6e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY49959.1 - 1.3e-09 37.9 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY49959.1 - 2.5e-08 34.2 0.0 5.9e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY49959.1 - 1e-07 31.9 0.0 2.5e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPY49959.1 - 0.004 16.8 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPY49959.1 - 0.015 14.9 0.1 0.12 11.9 0.0 2.3 3 0 0 3 3 3 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EPY49959.1 - 0.036 14.8 0.0 0.077 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ERCC4 PF02732.10 EPY49960.1 - 6.6e-24 84.2 0.9 1.5e-23 83.1 0.6 1.6 1 0 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.1 EPY49960.1 - 0.036 13.8 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix MRP-L47 PF06984.8 EPY49961.1 - 2e-32 110.9 0.6 3.2e-32 110.3 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 EPY49961.1 - 0.12 11.6 0.1 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Clc-like PHD PF00628.24 EPY49962.1 - 3.8e-10 39.3 7.6 6e-10 38.6 5.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EPY49962.1 - 0.001 18.3 2.4 0.0026 17.0 1.6 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-piccolo PF05715.8 EPY49962.1 - 0.0098 15.8 2.7 0.0098 15.8 1.9 1.9 2 0 0 2 2 2 1 Piccolo Zn-finger Prok-RING_1 PF14446.1 EPY49962.1 - 0.018 14.7 2.6 0.033 13.8 1.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.11 EPY49962.1 - 0.019 14.8 0.5 0.034 14.0 0.4 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.1 EPY49962.1 - 0.068 12.4 7.5 0.29 10.4 5.2 2.0 1 1 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EPY49962.1 - 0.29 10.9 6.2 0.086 12.5 1.0 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EPY49962.1 - 0.53 10.1 4.0 1.3 8.8 2.8 1.7 1 1 0 1 1 1 0 Double zinc ribbon Tnp_zf-ribbon_2 PF13842.1 EPY49962.1 - 6.1 7.3 6.0 2.5 8.5 1.4 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Pkinase PF00069.20 EPY49963.1 - 2.9e-68 229.8 0.0 3.9e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY49963.1 - 3.1e-30 105.0 0.0 4.2e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY49963.1 - 1.1e-08 34.3 0.0 2.8e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EPY49963.1 - 4.1e-05 24.0 0.5 9.4e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EPY49963.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.13 EPY49964.1 - 4.9e-32 111.1 0.5 1.8e-31 109.3 0.0 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PSI_PsaH PF03244.9 EPY49964.1 - 0.018 14.3 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI BHD_3 PF10405.4 EPY49965.1 - 3e-29 100.5 0.1 5.7e-29 99.6 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EPY49965.1 - 1.2e-24 86.4 2.3 1.2e-24 86.4 1.6 2.6 2 1 1 3 3 3 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EPY49965.1 - 1.9e-16 59.2 1.3 4.1e-16 58.2 0.2 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EPY49965.1 - 1.9e-15 56.9 0.1 1.9e-15 56.9 0.1 2.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EPY49965.1 - 0.0019 18.4 0.0 0.0053 16.9 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF2418 PF10332.4 EPY49966.1 - 7.6e-27 93.5 2.4 7.6e-27 93.5 1.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) DUF1673 PF07895.6 EPY49966.1 - 0.35 10.3 9.5 0.039 13.4 1.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1673) Adeno_E3_14_5 PF04834.7 EPY49966.1 - 0.84 10.1 4.6 16 6.0 1.2 2.4 1 1 0 2 2 2 0 Early E3 14.5 kDa protein DUF3328 PF11807.3 EPY49966.1 - 3.2 7.3 7.5 1.2 8.7 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) zf-RING_2 PF13639.1 EPY49967.1 - 2.6e-13 49.5 8.3 2.6e-13 49.5 5.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EPY49967.1 - 1.2e-09 38.1 3.1 2.5e-09 37.1 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPY49967.1 - 1.4e-06 28.2 8.6 2.7e-06 27.3 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY49967.1 - 2.8e-06 26.8 7.8 6.4e-06 25.7 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY49967.1 - 2.1e-05 24.0 5.7 3.6e-05 23.3 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY49967.1 - 0.00022 20.8 7.6 0.00041 20.0 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPY49967.1 - 0.00038 20.2 2.7 0.00082 19.1 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EPY49967.1 - 0.002 17.6 3.3 0.004 16.6 2.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EPY49967.1 - 0.035 14.1 8.0 0.066 13.2 5.5 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EPY49967.1 - 0.22 11.5 6.8 0.42 10.6 4.7 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 EPY49967.1 - 0.68 9.7 5.3 5.7 6.7 4.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger PHD PF00628.24 EPY49967.1 - 0.74 9.5 6.3 1.4 8.7 4.4 1.5 1 0 0 1 1 1 0 PHD-finger CUE PF02845.11 EPY49968.1 - 3e-08 32.9 0.0 7e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain DnaJ PF00226.26 EPY49969.1 - 5.6e-24 83.6 4.0 1.5e-23 82.3 2.8 1.8 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPY49969.1 - 3e-23 81.4 0.0 3.1e-18 65.4 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPY49969.1 - 1.6e-11 44.0 12.8 3e-11 43.1 8.9 1.5 1 0 0 1 1 1 1 DnaJ central domain YcbB PF08664.5 EPY49969.1 - 0.19 11.4 0.4 0.47 10.2 0.1 1.6 1 1 0 1 1 1 0 YcbB domain Cytochrome_CBB3 PF13442.1 EPY49969.1 - 0.4 10.8 2.7 5.7 7.1 1.0 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III NOT2_3_5 PF04153.13 EPY49970.1 - 1.2e-34 119.0 0.6 1.8e-34 118.5 0.4 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family dCMP_cyt_deam_1 PF00383.17 EPY49971.1 - 1.3e-21 76.1 0.2 1.9e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Methyltransf_16 PF10294.4 EPY49971.1 - 2.4e-17 62.9 0.0 4.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase APOBEC_N PF08210.6 EPY49971.1 - 0.00034 20.3 0.1 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Methyltransf_31 PF13847.1 EPY49971.1 - 0.022 14.3 0.0 0.072 12.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Myb_DNA-bind_2 PF08914.6 EPY49971.1 - 0.028 14.2 0.0 0.089 12.6 0.0 1.8 2 0 0 2 2 2 0 Rap1 Myb domain HD_3 PF13023.1 EPY49972.1 - 1.1e-41 142.3 0.5 1.3e-41 142.0 0.4 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EPY49972.1 - 1.7e-06 28.0 0.5 2.5e-06 27.4 0.3 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 EPY49972.1 - 0.014 15.2 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme RIX1 PF08167.7 EPY49973.1 - 1.6e-42 145.0 3.9 1.6e-42 145.0 2.7 3.7 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis Ssl1 PF04056.9 EPY49974.1 - 1.2e-84 282.7 0.2 1.6e-84 282.3 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EPY49974.1 - 7.1e-18 64.3 17.0 7.1e-18 64.3 11.8 2.8 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EPY49974.1 - 3.3e-08 33.8 0.0 4.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EPY49974.1 - 0.0018 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc_ribbon_4 PF13717.1 EPY49974.1 - 0.14 11.8 12.8 0.63 9.7 1.3 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPY49974.1 - 0.46 10.1 13.8 1.5 8.4 1.9 3.6 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 EPY49974.1 - 3.6 7.5 28.0 0.023 14.5 8.2 2.9 2 1 0 2 2 2 0 IBR domain PUF PF00806.14 EPY49975.1 - 9.9e-39 128.6 8.7 4e-07 29.1 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Mito_carr PF00153.22 EPY49976.1 - 9.1e-26 89.4 1.8 2.7e-14 52.6 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein MitMem_reg PF13012.1 EPY49977.1 - 5.6e-37 126.3 0.8 1.1e-36 125.3 0.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EPY49977.1 - 5.6e-26 90.5 0.0 1.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Choline_transpo PF04515.7 EPY49978.1 - 9.5e-08 31.1 44.9 4.2e-06 25.7 18.9 3.1 3 0 0 3 3 3 2 Plasma-membrane choline transporter UCH PF00443.24 EPY49979.1 - 6.6e-61 205.7 0.8 8.8e-61 205.3 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY49979.1 - 1.3e-26 93.6 0.3 1.3e-26 93.6 0.2 1.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2296 PF10058.4 EPY49979.1 - 0.0052 16.5 1.5 0.23 11.2 0.2 3.3 3 0 0 3 3 3 1 Predicted integral membrane metal-binding protein (DUF2296) Peptidase_C98 PF15499.1 EPY49979.1 - 0.031 13.5 3.8 2.8 7.1 0.0 3.3 3 1 1 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase SWIRM PF04433.12 EPY49980.1 - 1.8e-15 56.7 0.0 5.5e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 SWIRM domain Ribosomal_L19e PF01280.15 EPY49981.1 - 2.3e-61 205.9 9.4 2.3e-61 205.9 6.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e PXA PF02194.10 EPY49982.1 - 4.4e-24 85.0 3.0 9.5e-24 83.9 0.2 2.8 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EPY49982.1 - 3.2e-06 27.2 0.0 0.00021 21.3 0.0 2.6 1 1 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EPY49982.1 - 0.034 13.9 0.5 0.14 11.9 0.1 2.3 2 0 0 2 2 2 0 PX domain DUF2633 PF11119.3 EPY49982.1 - 3.2 7.5 5.6 8 6.2 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) AAA PF00004.24 EPY49983.1 - 2.9e-43 147.2 0.0 4.5e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPY49983.1 - 4.5e-07 30.0 0.0 1.8e-05 24.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EPY49983.1 - 1e-06 28.5 0.5 5.1e-05 23.0 0.1 3.0 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPY49983.1 - 1.8e-06 27.1 0.0 3.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPY49983.1 - 2.3e-05 24.5 0.0 0.0028 17.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EPY49983.1 - 3.1e-05 23.9 0.0 8.5e-05 22.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EPY49983.1 - 5.5e-05 23.9 0.3 0.00014 22.6 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EPY49983.1 - 0.00023 20.8 0.1 0.00056 19.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EPY49983.1 - 0.00068 19.9 0.1 0.0021 18.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 EPY49983.1 - 0.00083 18.1 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EPY49983.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPY49983.1 - 0.0013 17.6 0.0 0.0029 16.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EPY49983.1 - 0.0029 17.0 0.2 0.019 14.3 0.1 2.1 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPY49983.1 - 0.0036 16.7 0.1 0.007 15.8 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPY49983.1 - 0.0038 16.4 0.0 0.0092 15.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EPY49983.1 - 0.0095 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPY49983.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPY49983.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 EPY49983.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EPY49983.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EPY49983.1 - 0.019 14.0 0.0 0.13 11.3 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EPY49983.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 EPY49983.1 - 0.028 14.0 0.4 0.052 13.1 0.1 1.5 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EPY49983.1 - 0.036 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EPY49983.1 - 0.039 13.4 0.1 0.2 11.1 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EPY49983.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EPY49983.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PRA1 PF03208.14 EPY49984.1 - 2e-31 108.4 0.2 2.3e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein Cnd2 PF05786.9 EPY49985.1 - 4e-159 531.4 15.5 5e-159 531.1 10.7 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 N-SET PF11764.3 EPY49986.1 - 1.9e-28 99.4 0.0 1.9e-28 99.4 0.0 3.5 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 EPY49986.1 - 4.6e-24 85.5 0.4 4.6e-24 85.5 0.3 3.2 3 1 0 3 3 3 1 SET domain SET_assoc PF11767.3 EPY49986.1 - 1.2e-19 69.3 1.7 1.2e-19 69.3 1.2 1.9 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 EPY49986.1 - 2.3e-11 43.1 0.0 1.5e-08 34.1 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY49986.1 - 3.5e-08 33.3 0.0 7.3e-06 25.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Atrophin-1 PF03154.10 EPY49986.1 - 0.039 12.1 19.8 0.06 11.4 13.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family NYN_YacP PF05991.6 EPY49986.1 - 0.068 12.9 6.6 0.14 11.9 3.9 2.0 2 0 0 2 2 2 0 YacP-like NYN domain Prog_receptor PF02161.10 EPY49986.1 - 0.31 9.8 5.4 0.57 8.9 3.8 1.3 1 0 0 1 1 1 0 Progesterone receptor TilS_C PF11734.3 EPY49986.1 - 0.5 9.6 2.6 1.4 8.1 1.8 1.8 1 0 0 1 1 1 0 TilS substrate C-terminal domain INSIG PF07281.7 EPY49987.1 - 2.7e-40 137.7 4.8 3.3e-40 137.4 3.3 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Sec7_N PF12783.2 EPY49987.1 - 0.058 12.8 0.1 0.099 12.0 0.1 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal O-antigen_lig PF13425.1 EPY49987.1 - 1.9 8.4 10.8 0.73 9.8 1.4 2.5 1 1 1 2 2 2 0 O-antigen ligase like membrane protein ATP-synt_S1 PF05827.7 EPY49988.1 - 7.9e-31 107.4 4.6 9.6e-31 107.1 3.2 1.1 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Ribosomal_L1 PF00687.16 EPY49989.1 - 4e-37 127.7 1.7 5.1e-37 127.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DnaI_N PF07319.6 EPY49989.1 - 0.61 10.3 3.3 17 5.7 0.1 3.2 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus Ldh_1_N PF00056.18 EPY49990.1 - 8.4e-40 135.8 0.3 1.4e-39 135.1 0.1 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EPY49990.1 - 9.9e-38 129.5 0.0 1.3e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EPY49990.1 - 3.8e-05 22.5 0.0 5.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EPY49990.1 - 0.0019 18.1 0.1 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPY49990.1 - 0.0022 18.3 0.1 0.0085 16.3 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EPY49990.1 - 0.011 14.8 0.1 0.1 11.6 0.1 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EPY49990.1 - 0.037 14.0 0.6 0.11 12.4 0.4 1.8 1 1 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 EPY49990.1 - 0.06 12.3 0.1 0.088 11.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase CAP_N PF01213.14 EPY49991.1 - 1.2e-97 326.9 12.5 9.4e-74 248.4 0.7 2.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EPY49991.1 - 4.2e-59 198.4 5.2 6.3e-59 197.8 3.6 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EPY49991.1 - 9.8e-05 21.7 4.7 0.00021 20.6 3.3 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF1040 PF06288.8 EPY49994.1 - 0.12 12.5 0.9 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) EF-hand_7 PF13499.1 EPY49995.1 - 2.9e-25 88.1 10.8 6.9e-13 48.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EPY49995.1 - 5.2e-25 84.8 17.2 1.8e-07 29.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EPY49995.1 - 1.3e-23 80.6 10.7 4e-08 32.4 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EPY49995.1 - 8.9e-16 56.4 14.2 0.00045 19.4 0.0 4.6 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 EPY49995.1 - 3.5e-14 52.1 14.8 7.2e-08 31.9 0.9 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EPY49995.1 - 1.4e-07 31.3 0.6 0.00028 20.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EPY49995.1 - 4.4e-05 23.1 6.1 0.014 15.1 1.1 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand PaaX_C PF08223.6 EPY49995.1 - 0.076 12.7 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Metal_resist PF13801.1 EPY49995.1 - 0.22 11.4 2.9 0.11 12.4 0.5 1.6 2 0 0 2 2 2 0 Heavy-metal resistance DUF3664 PF12406.3 EPY49996.1 - 0.29 11.7 7.1 0.69 10.5 4.9 1.6 1 0 0 1 1 1 0 Surface protein eIF-3c_N PF05470.7 EPY49996.1 - 1.6 6.7 12.3 2.5 6.0 8.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MCM PF00493.18 EPY49997.1 - 2.6e-126 420.9 0.1 3.8e-126 420.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPY49997.1 - 2.4e-18 66.7 0.0 8e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPY49997.1 - 7.8e-08 31.7 0.2 1.8e-06 27.2 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPY49997.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPY49997.1 - 0.01 15.3 0.0 0.044 13.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain UCR_UQCRX_QCR9 PF05365.7 EPY49998.1 - 4.8e-23 80.5 3.5 5.3e-23 80.3 2.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF3392 PF11872.3 EPY49999.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3392) PX PF00787.19 EPY50000.1 - 1.2e-15 57.2 0.9 2.7e-15 56.1 0.6 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EPY50000.1 - 1.1e-09 37.8 4.8 1.1e-09 37.8 3.3 2.2 2 0 0 2 2 2 1 SNARE domain PHD PF00628.24 EPY50001.1 - 1.7e-12 46.7 5.4 1.7e-12 46.7 3.7 1.9 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 EPY50001.1 - 0.0037 16.7 3.5 0.015 14.7 0.4 2.6 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain DUF3795 PF12675.2 EPY50001.1 - 1.3 9.1 8.4 3.6 7.8 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) DUF1295 PF06966.7 EPY50002.1 - 1.6e-60 204.3 7.7 2.1e-60 203.9 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EPY50002.1 - 0.024 14.8 0.0 0.024 14.8 0.0 2.5 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NAF PF03822.9 EPY50002.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 NAF domain DUF2456 PF10445.4 EPY50003.1 - 9e-33 112.0 3.3 9e-33 112.0 2.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) DUF1769 PF08588.5 EPY50004.1 - 1.9e-21 75.7 0.3 4.4e-21 74.5 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Pil1 PF13805.1 EPY50005.1 - 1.4e-136 453.9 0.2 1.8e-136 453.6 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 V_ATPase_I PF01496.14 EPY50005.1 - 0.087 10.6 1.2 0.12 10.1 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HEAT PF02985.17 EPY50006.1 - 0.00075 19.3 1.0 5.4 7.3 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat IncA PF04156.9 EPY50006.1 - 0.036 13.6 14.1 0.073 12.6 9.8 1.4 1 0 0 1 1 1 0 IncA protein DUF3800 PF12686.2 EPY50006.1 - 0.12 12.0 0.1 2.1 7.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3800) Troponin PF00992.15 EPY50006.1 - 1.9 8.5 11.4 3.5 7.7 2.4 2.5 1 1 1 2 2 2 0 Troponin adh_short PF00106.20 EPY50007.1 - 3.8e-14 52.9 0.0 6.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EPY50007.1 - 4.5e-06 26.2 0.3 6.4e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPY50007.1 - 1.3e-05 24.9 0.1 3.5e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EPY50007.1 - 5e-05 23.2 0.0 0.00012 21.9 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPY50007.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding YTH PF04146.10 EPY50008.1 - 2.9e-15 56.0 0.0 4.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Piwi PF02171.12 EPY50009.1 - 8.4e-96 320.4 0.1 1.5e-95 319.6 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EPY50009.1 - 9.5e-25 86.4 1.3 2.1e-24 85.3 0.9 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EPY50009.1 - 4.4e-18 64.3 0.3 1.1e-17 63.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF4491 PF14898.1 EPY50010.1 - 0.36 11.0 3.2 0.16 12.0 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) Pro_isomerase PF00160.16 EPY50011.1 - 9.8e-47 159.0 0.0 1.7e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EPY50011.1 - 3.2e-07 29.9 3.2 0.00056 19.6 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat AAA PF00004.24 EPY50012.1 - 5.6e-52 175.4 0.0 2.4e-39 134.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EPY50012.1 - 4e-15 55.6 0.0 8.9e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_14 PF13173.1 EPY50012.1 - 3.8e-09 36.5 0.0 0.00011 22.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPY50012.1 - 3.9e-09 36.7 8.0 0.0098 15.8 0.1 4.2 2 2 2 4 4 4 2 AAA ATPase domain NACHT PF05729.7 EPY50012.1 - 4.2e-08 33.0 3.3 0.03 13.9 1.0 4.7 4 1 0 4 4 3 2 NACHT domain AAA_22 PF13401.1 EPY50012.1 - 4.6e-07 30.0 2.0 0.2 11.8 0.2 4.7 2 2 2 4 4 4 2 AAA domain AAA_17 PF13207.1 EPY50012.1 - 6.9e-06 26.8 0.0 0.14 12.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPY50012.1 - 1.4e-05 25.0 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EPY50012.1 - 1.6e-05 24.3 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EPY50012.1 - 2.8e-05 23.9 0.5 0.18 11.4 0.0 3.7 2 2 2 4 4 4 1 Archaeal ATPase AAA_5 PF07728.9 EPY50012.1 - 9.2e-05 22.1 0.1 0.11 12.2 0.0 3.4 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPY50012.1 - 0.0001 22.6 0.0 0.11 12.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.22 EPY50012.1 - 0.00013 22.3 0.2 0.34 11.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter FtsK_SpoIIIE PF01580.13 EPY50012.1 - 0.00024 20.6 0.0 0.00078 18.9 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 EPY50012.1 - 0.00024 20.6 0.0 0.02 14.3 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EPY50012.1 - 0.00025 20.6 0.7 0.67 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPY50012.1 - 0.00047 19.6 0.6 3.9 6.8 0.0 3.6 3 1 1 4 4 4 1 AAA domain DUF815 PF05673.8 EPY50012.1 - 0.001 18.0 0.0 0.24 10.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EPY50012.1 - 0.0012 19.0 0.0 0.52 10.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase T2SE PF00437.15 EPY50012.1 - 0.0012 17.7 0.1 0.0062 15.4 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EPY50012.1 - 0.0015 17.6 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 EPY50012.1 - 0.0021 17.5 0.0 2.3 7.6 0.0 3.0 4 0 0 4 4 3 1 Sigma-54 interaction domain NB-ARC PF00931.17 EPY50012.1 - 0.0044 15.9 0.0 1.2 7.9 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_2 PF07724.9 EPY50012.1 - 0.0047 16.8 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) UPF0079 PF02367.12 EPY50012.1 - 0.005 16.4 0.1 2.3 7.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 EPY50012.1 - 0.012 15.2 0.4 0.3 10.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein MobB PF03205.9 EPY50012.1 - 0.015 15.0 0.3 0.22 11.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EPY50012.1 - 0.017 14.0 0.1 7.3 5.4 0.0 2.9 3 0 0 3 3 3 0 PIF1-like helicase AAA_29 PF13555.1 EPY50012.1 - 0.018 14.5 0.5 1.3 8.5 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EPY50012.1 - 0.025 14.3 0.2 2.9 7.7 0.0 3.2 4 0 0 4 4 3 0 Part of AAA domain RuvB_N PF05496.7 EPY50012.1 - 0.027 13.5 0.0 0.12 11.4 0.0 2.0 2 1 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EPY50012.1 - 0.034 13.3 0.0 8.8 5.4 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI cobW PF02492.14 EPY50012.1 - 0.038 13.4 0.5 0.21 11.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 EPY50012.1 - 0.045 12.9 0.3 0.9 8.7 0.1 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EPY50012.1 - 0.059 13.8 0.4 2.6 8.5 0.1 3.2 3 0 0 3 3 3 0 Miro-like protein ATP-synt_ab PF00006.20 EPY50012.1 - 0.07 12.6 0.1 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EPY50012.1 - 0.082 12.3 0.2 12 5.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.8 EPY50012.1 - 0.097 11.3 0.0 2.1 6.9 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus CN_hydrolase PF00795.17 EPY50013.1 - 2e-30 105.5 0.0 3.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EPY50013.1 - 1.1e-22 80.1 0.0 3.8e-22 78.3 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EPY50013.1 - 0.057 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase DUF2439 PF10382.4 EPY50014.1 - 2.6e-21 75.5 1.1 7.2e-21 74.1 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) tRNA-synt_2d PF01409.15 EPY50016.1 - 1.6e-47 161.7 0.2 2.7e-26 92.2 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EPY50016.1 - 4e-24 84.6 0.1 1.4e-23 82.8 0.1 2.0 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EPY50016.1 - 0.07 11.8 0.1 0.47 9.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Glyco_transf_34 PF05637.7 EPY50017.1 - 3.6e-79 265.6 0.1 5.1e-79 265.1 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Scm3 PF10384.4 EPY50017.1 - 0.14 11.6 0.2 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Centromere protein Scm3 tRNA-synt_2 PF00152.15 EPY50018.1 - 8.3e-115 383.1 0.0 1.3e-114 382.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPY50018.1 - 7.8e-07 28.8 0.2 3.9e-06 26.6 0.1 2.2 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EPY50018.1 - 3.5e-05 23.4 0.0 0.073 12.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) DUF4131 PF13567.1 EPY50018.1 - 0.064 12.6 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TFIIH_BTF_p62_N PF08567.6 EPY50018.1 - 0.077 12.6 0.3 0.85 9.3 0.0 2.2 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain DUF3835 PF12927.2 EPY50019.1 - 4e-10 40.5 2.2 4e-10 40.5 1.5 7.1 7 1 0 7 7 7 4 Domain of unknown function (DUF3835) TMEM171 PF15471.1 EPY50019.1 - 1.4 7.6 3.7 1.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein family 171 LAG1-DNAbind PF09271.6 EPY50020.1 - 3.6e-22 79.3 5.8 2.9e-21 76.4 1.4 2.9 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 EPY50020.1 - 5.6e-19 68.4 0.0 1.7e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Beta-trefoil DNA-binding domain Translin PF01997.11 EPY50021.1 - 1.3e-46 158.7 0.7 1.6e-46 158.4 0.5 1.1 1 0 0 1 1 1 1 Translin family Ribosomal_S8 PF00410.14 EPY50022.1 - 5.2e-23 81.3 0.0 6.7e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribophorin_II PF05817.9 EPY50023.1 - 2.4e-13 49.1 2.1 2.7e-13 49.0 1.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II NVEALA PF14055.1 EPY50023.1 - 0.27 10.9 2.9 1.7 8.4 0.6 2.5 2 0 0 2 2 2 0 NVEALA protein IMS PF00817.15 EPY50024.1 - 1.4e-42 144.9 2.1 8.1e-42 142.5 0.1 2.7 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 EPY50024.1 - 2e-16 60.0 0.3 4.5e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF2338 PF10100.4 EPY50024.1 - 0.0034 15.8 0.3 0.03 12.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2338) IMS_HHH PF11798.3 EPY50024.1 - 0.0041 17.0 0.1 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF2847 PF11009.3 EPY50024.1 - 0.044 13.3 0.4 1.7 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) GTP_EFTU PF00009.22 EPY50025.1 - 5.3e-53 179.2 0.0 9.2e-53 178.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EPY50025.1 - 2.3e-13 49.8 0.0 6.4e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPY50025.1 - 1.8e-09 37.5 0.0 4.8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPY50025.1 - 3.6e-08 33.1 0.0 9.7e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EPY50025.1 - 0.00024 21.0 0.0 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_IV PF03764.13 EPY50025.1 - 0.00027 20.4 0.0 0.0044 16.5 0.0 2.9 1 1 0 1 1 1 1 Elongation factor G, domain IV DNA_pol_E_B PF04042.11 EPY50026.1 - 1.6e-41 141.8 0.6 3e-41 140.9 0.4 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EPY50026.1 - 5.1e-38 131.0 5.4 6.3e-25 88.1 0.7 2.3 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal GPI-anchored PF10342.4 EPY50027.1 - 8.5e-11 42.1 3.4 8.5e-11 42.1 2.4 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CAML PF14963.1 EPY50027.1 - 0.38 10.0 3.2 0.6 9.4 2.2 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TFIIA_gamma_N PF02268.11 EPY50028.1 - 1.7e-27 94.6 0.2 2.5e-27 94.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EPY50028.1 - 2.9e-25 87.8 0.8 4e-25 87.3 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF3971 PF13116.1 EPY50028.1 - 0.08 12.3 0.0 0.096 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function Epimerase_Csub PF13950.1 EPY50028.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit MFS_1_like PF12832.2 EPY50029.1 - 3.9e-18 65.0 3.3 3.9e-18 65.0 2.3 3.3 3 1 0 3 3 3 1 MFS_1 like family RAI1 PF08652.6 EPY50029.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Malic_M PF03949.10 EPY50031.1 - 3.6e-83 279.0 0.4 6.2e-83 278.2 0.1 1.5 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.14 EPY50031.1 - 5.1e-60 202.1 0.0 8.2e-60 201.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ENTH PF01417.15 EPY50032.1 - 2.6e-45 153.3 0.4 3.8e-45 152.7 0.3 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EPY50032.1 - 3.8e-05 22.5 0.0 5.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EPY50032.1 - 0.048 13.2 0.1 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 VHS domain Asp_Glu_race_2 PF14669.1 EPY50032.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase UDPGP PF01704.13 EPY50033.1 - 1.7e-172 573.6 0.1 2.1e-172 573.3 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Hexapep PF00132.19 EPY50033.1 - 0.21 11.1 2.7 5 6.8 0.3 2.7 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) DUF2419 PF10343.4 EPY50034.1 - 5.6e-14 52.0 0.0 1.2e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) GTP_EFTU PF00009.22 EPY50035.1 - 6.3e-57 192.0 0.1 1.2e-56 191.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPY50035.1 - 2.6e-36 123.7 0.0 9e-36 122.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPY50035.1 - 2.6e-33 113.9 8.8 4.2e-16 58.8 0.8 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPY50035.1 - 1e-10 41.0 3.5 0.00022 20.8 0.1 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPY50035.1 - 0.0021 17.9 0.4 0.0059 16.5 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase 2-oxoacid_dh PF00198.18 EPY50037.1 - 1.9e-83 279.2 0.1 2.7e-83 278.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPY50037.1 - 5e-17 61.3 0.3 1.2e-16 60.1 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EPY50037.1 - 1.3e-16 59.8 0.0 3.5e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Med3 PF11593.3 EPY50037.1 - 0.021 14.0 2.0 0.034 13.4 1.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PadR PF03551.9 EPY50037.1 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DNA_alkylation PF08713.6 EPY50037.1 - 0.075 12.5 0.5 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 DNA alkylation repair enzyme SLAC1 PF03595.12 EPY50038.1 - 1.5e-72 244.0 40.3 1.7e-72 243.8 28.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MFS_1 PF07690.11 EPY50040.1 - 1.3e-34 119.4 31.6 1.3e-34 119.4 21.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY50040.1 - 1.7e-10 40.0 9.2 1.7e-10 40.0 6.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter FANCL_C PF11793.3 EPY50041.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain AA_permease_2 PF13520.1 EPY50042.1 - 5.8e-44 150.2 42.0 7.5e-44 149.9 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPY50042.1 - 9.5e-21 73.6 36.8 1.3e-20 73.2 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EPY50043.1 - 4.5e-39 134.1 20.0 4.5e-39 134.1 13.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY50043.1 - 1e-12 47.4 5.7 1e-12 47.4 4.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPY50043.1 - 0.00045 18.5 1.1 0.00074 17.8 0.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPY50043.1 - 0.00089 17.4 0.6 0.0015 16.7 0.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector UNC-93 PF05978.11 EPY50043.1 - 0.013 15.0 0.5 0.013 15.0 0.3 2.3 4 0 0 4 4 4 0 Ion channel regulatory protein UNC-93 OATP PF03137.15 EPY50043.1 - 0.35 8.8 9.6 0.89 7.5 3.0 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EPY50044.1 - 1.4e-122 409.5 25.4 1.4e-122 409.5 17.6 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY50044.1 - 1.5e-18 66.6 26.4 3.7e-15 55.4 9.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 EPY50045.1 - 1.4e-12 47.2 9.8 1.4e-12 47.2 6.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPY50045.1 - 5.3e-11 42.3 10.7 5.3e-11 42.3 7.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY50045.1 - 1.1e-09 37.8 11.0 1.1e-09 37.8 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY50045.1 - 2e-09 36.9 8.0 2e-09 36.9 5.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPY50045.1 - 4.7e-09 35.9 10.8 4.7e-09 35.9 7.5 2.1 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EPY50045.1 - 2.6e-08 33.4 9.3 2.6e-08 33.4 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPY50045.1 - 1.8e-06 27.5 3.8 3.8e-06 26.5 2.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EPY50045.1 - 7.8e-05 22.7 6.8 7.8e-05 22.7 4.7 2.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EPY50045.1 - 0.00061 19.5 6.5 0.0028 17.3 1.7 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EPY50045.1 - 0.0082 15.9 3.4 0.023 14.5 2.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 EPY50045.1 - 0.0092 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.1 EPY50045.1 - 0.014 14.9 9.0 0.014 14.9 6.2 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EPY50045.1 - 0.035 13.9 15.7 0.6 9.9 0.5 3.1 2 1 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EPY50045.1 - 0.053 13.3 15.1 0.49 10.2 5.2 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-Nse PF11789.3 EPY50045.1 - 0.055 12.9 6.9 0.14 11.6 4.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF983 PF06170.7 EPY50045.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF983) Na_trans_assoc PF06512.8 EPY50045.1 - 4.7 7.1 13.5 2.2 8.1 5.4 2.5 2 1 0 2 2 2 0 Sodium ion transport-associated Urm1 PF09138.6 EPY50046.1 - 8.4e-31 105.9 0.2 9.3e-31 105.8 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EPY50046.1 - 3.7e-07 30.4 0.0 4.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ThiS family DUF777 PF05606.6 EPY50046.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.2 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) DAGAT PF03982.8 EPY50047.1 - 2.8e-92 308.5 0.0 3.4e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Sugar_tr PF00083.19 EPY50048.1 - 5.2e-116 387.8 24.5 6.1e-116 387.6 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY50048.1 - 1.3e-18 66.8 29.6 2.2e-14 52.9 6.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ring_hydroxyl_A PF00848.14 EPY50049.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Sugar_tr PF00083.19 EPY50050.1 - 1.7e-118 396.0 28.0 2e-118 395.8 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY50050.1 - 9.2e-19 67.3 29.9 1e-14 54.0 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EPY50050.1 - 0.17 9.9 4.9 0.25 9.3 3.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector PRA1 PF03208.14 EPY50050.1 - 2.6 7.3 8.0 0.11 11.7 0.4 2.6 3 0 0 3 3 3 0 PRA1 family protein MPC PF03650.8 EPY50051.1 - 2.8e-38 130.5 0.2 3.5e-38 130.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Sec6 PF06046.8 EPY50052.1 - 2.2e-128 428.8 3.4 2.9e-128 428.4 2.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 WD40 PF00400.27 EPY50053.1 - 6e-26 89.3 11.6 3.4e-06 26.7 0.1 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat LisH PF08513.6 EPY50053.1 - 4.9e-10 38.7 0.1 1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EPY50053.1 - 6.9e-08 32.4 0.4 0.003 17.3 0.1 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EPY50053.1 - 0.071 12.6 1.8 21 4.7 0.0 3.8 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain CENP-Q PF13094.1 EPY50054.1 - 1.3e-11 44.7 13.9 1.3e-11 44.7 9.6 2.2 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Vma12 PF11712.3 EPY50054.1 - 0.4 10.3 4.0 0.77 9.4 2.7 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Exonuc_VII_L PF02601.10 EPY50054.1 - 4.9 6.2 9.1 8.2 5.5 6.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF904 PF06005.7 EPY50054.1 - 9.8 6.5 16.5 1.9 8.8 5.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF904) GET2 PF08690.5 EPY50055.1 - 1e-07 31.4 9.8 4e-07 29.5 4.7 2.2 1 1 0 2 2 2 2 GET complex subunit GET2 CAML PF14963.1 EPY50055.1 - 0.0008 18.8 1.3 0.002 17.5 0.9 1.5 1 1 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand VMA21 PF09446.5 EPY50056.1 - 7.3e-12 45.0 9.0 9.2e-12 44.7 6.2 1.1 1 0 0 1 1 1 1 VMA21-like domain MFS_2 PF13347.1 EPY50056.1 - 0.00013 20.5 0.1 0.00013 20.5 0.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DUF1634 PF07843.6 EPY50056.1 - 0.0052 16.3 1.0 0.0067 16.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1634) DUF4149 PF13664.1 EPY50056.1 - 0.0068 16.4 2.6 0.008 16.2 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) DUF2232 PF09991.4 EPY50056.1 - 0.014 14.4 1.2 0.016 14.2 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) LrgB PF04172.11 EPY50056.1 - 0.025 13.7 0.3 0.03 13.4 0.2 1.0 1 0 0 1 1 1 0 LrgB-like family DUF4293 PF14126.1 EPY50056.1 - 0.027 14.4 0.2 0.03 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF1772 PF08592.6 EPY50056.1 - 0.036 13.8 0.3 0.041 13.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF3784 PF12650.2 EPY50056.1 - 0.04 13.8 0.5 0.048 13.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) VIT1 PF01988.14 EPY50056.1 - 0.16 11.4 1.3 0.18 11.3 0.9 1.0 1 0 0 1 1 1 0 VIT family DUF3262 PF11660.3 EPY50056.1 - 2.1 8.4 8.1 3.8 7.6 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3262) SNF2_N PF00176.18 EPY50057.1 - 1.1e-65 221.3 0.1 1.6e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY50057.1 - 7.3e-15 54.5 0.0 5.2e-14 51.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY50057.1 - 1.8e-08 34.0 0.0 4.8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPY50057.1 - 2.3e-08 34.0 0.1 1.1e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPY50057.1 - 0.0071 16.4 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain PAPS_reduct PF01507.14 EPY50058.1 - 5e-35 120.8 0.0 2.3e-20 73.1 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Smr PF01713.16 EPY50059.1 - 7.7e-14 51.6 0.0 2.2e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Smr domain PMC2NT PF08066.7 EPY50059.1 - 0.08 13.2 2.1 19 5.6 0.9 3.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain BATS PF06968.8 EPY50060.1 - 3.5e-25 87.6 0.0 1.3e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EPY50060.1 - 6.2e-18 65.5 0.1 1.2e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fungal_trans PF04082.13 EPY50062.1 - 2.4e-13 49.5 0.5 6.3e-13 48.1 0.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY50062.1 - 6.6e-10 38.7 8.0 1.2e-09 37.9 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Miro PF08477.8 EPY50063.1 - 7.8e-39 132.8 0.0 1.9e-20 73.5 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EPY50063.1 - 3.8e-29 99.7 0.6 8.5e-29 98.6 0.4 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 EPY50063.1 - 3.2e-27 94.1 0.1 9.2e-27 92.6 0.0 1.8 2 0 0 2 2 1 1 EF hand associated Ras PF00071.17 EPY50063.1 - 4.7e-20 71.5 0.0 3.2e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EPY50063.1 - 7.9e-08 32.2 0.1 0.00014 21.8 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPY50063.1 - 1.4e-07 31.7 0.0 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EPY50063.1 - 1.4e-06 28.5 0.0 0.01 15.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EPY50063.1 - 1.9e-06 27.1 0.0 0.0036 16.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EPY50063.1 - 4.9e-06 26.4 0.0 0.018 14.7 0.0 2.6 2 0 0 2 2 2 2 Archaeal ATPase AAA_21 PF13304.1 EPY50063.1 - 6e-06 26.4 0.3 0.0012 18.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPY50063.1 - 6.3e-06 26.5 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RNA_helicase PF00910.17 EPY50063.1 - 1.3e-05 25.3 0.0 0.55 10.4 0.0 3.5 3 0 0 3 3 3 2 RNA helicase EF-hand_7 PF13499.1 EPY50063.1 - 2.5e-05 24.3 2.6 0.15 12.1 0.9 2.7 2 0 0 2 2 2 2 EF-hand domain pair MobB PF03205.9 EPY50063.1 - 2.7e-05 23.9 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPY50063.1 - 3.2e-05 23.6 0.0 0.073 12.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain EF-hand_1 PF00036.27 EPY50063.1 - 9e-05 21.5 3.5 0.036 13.3 1.2 3.3 3 0 0 3 3 2 1 EF hand GTP_EFTU PF00009.22 EPY50063.1 - 0.00014 21.3 0.0 0.32 10.4 0.0 3.8 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EPY50063.1 - 0.00016 21.1 0.1 0.17 11.4 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain EF-hand_8 PF13833.1 EPY50063.1 - 0.00016 21.2 2.6 0.0038 16.8 0.8 3.1 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.18 EPY50063.1 - 0.0003 20.6 0.4 0.028 14.2 0.1 2.7 2 1 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 EPY50063.1 - 0.00048 19.2 0.0 0.24 10.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EPY50063.1 - 0.00089 18.9 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_6 PF13405.1 EPY50063.1 - 0.00098 18.8 5.3 0.028 14.3 1.5 2.9 2 0 0 2 2 2 1 EF-hand domain AAA_23 PF13476.1 EPY50063.1 - 0.0011 19.3 0.2 1.4 9.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 EPY50063.1 - 0.0016 18.6 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) EF-hand_5 PF13202.1 EPY50063.1 - 0.0019 17.4 2.8 0.0052 16.0 1.9 1.8 1 0 0 1 1 1 1 EF hand cobW PF02492.14 EPY50063.1 - 0.0024 17.3 0.0 1.7 8.0 0.0 3.1 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EPY50063.1 - 0.0028 16.7 0.0 0.32 9.9 0.0 2.3 2 0 0 2 2 2 1 Septin DUF815 PF05673.8 EPY50063.1 - 0.0032 16.4 0.0 0.14 11.0 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 EPY50063.1 - 0.0064 15.3 0.0 0.2 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.1 EPY50063.1 - 0.0084 16.0 0.0 3.9 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPY50063.1 - 0.01 15.7 0.0 6 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EPY50063.1 - 0.01 15.3 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EPY50063.1 - 0.013 14.4 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein IIGP PF05049.8 EPY50063.1 - 0.015 14.1 0.0 4.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.12 EPY50063.1 - 0.018 14.5 0.1 43 3.5 0.0 3.8 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.10 EPY50063.1 - 0.02 13.5 0.1 2.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.13 EPY50063.1 - 0.021 14.3 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 EPY50063.1 - 0.027 13.5 0.6 4.7 6.1 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EPY50063.1 - 0.029 13.8 0.0 4.8 6.6 0.0 3.4 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EPY50063.1 - 0.031 14.5 0.0 1.9 8.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EPY50063.1 - 0.035 13.6 0.0 2.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EPY50063.1 - 0.038 13.9 3.1 1.8 8.4 0.0 3.4 3 1 1 4 4 3 0 AAA domain AAA_25 PF13481.1 EPY50063.1 - 0.039 13.3 0.0 18 4.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 EPY50063.1 - 0.041 13.3 0.0 4.6 6.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Arf PF00025.16 EPY50063.1 - 0.047 12.9 0.0 1.5 8.0 0.0 2.9 3 1 0 3 3 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 EPY50063.1 - 0.052 12.9 0.2 11 5.3 0.1 2.6 2 1 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EPY50063.1 - 0.053 14.3 0.0 16 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 EPY50063.1 - 0.063 12.7 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase TrwB_AAD_bind PF10412.4 EPY50063.1 - 0.068 11.7 0.0 1.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SMC_N PF02463.14 EPY50063.1 - 0.069 12.3 0.1 5.9 6.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_32 PF13654.1 EPY50063.1 - 0.13 10.9 0.0 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EPY50063.1 - 0.14 11.5 0.0 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EPY50063.1 - 0.14 11.8 0.1 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 NTPase Sulfate_transp PF00916.15 EPY50064.1 - 2.4e-42 144.8 14.3 4.5e-42 143.9 9.9 1.5 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EPY50064.1 - 8.7e-21 73.5 0.0 1.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sulfate_tra_GLY PF13792.1 EPY50064.1 - 1.8e-20 72.3 4.9 9.4e-20 70.0 3.2 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif R3H-assoc PF13902.1 EPY50065.1 - 2.5e-06 27.4 0.2 3.9e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain RRM_1 PF00076.17 EPY50066.1 - 1.1e-18 66.6 0.1 2.3e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50066.1 - 1.7e-06 27.9 0.0 0.074 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50066.1 - 6.6e-06 25.8 0.0 0.049 13.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF914 PF06027.7 EPY50067.1 - 7.6e-115 383.3 20.7 1.3e-114 382.5 14.4 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EPY50067.1 - 1e-06 28.8 12.3 1e-06 28.8 8.6 3.6 2 2 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EPY50067.1 - 2.1e-05 24.6 10.0 2.1e-05 24.6 6.9 2.9 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EPY50067.1 - 0.0076 15.2 20.1 0.77 8.6 13.9 2.1 1 1 0 1 1 1 1 UAA transporter family DUF3611 PF12263.3 EPY50067.1 - 0.022 14.1 0.3 0.022 14.1 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) TPT PF03151.11 EPY50067.1 - 0.33 10.5 24.4 0.039 13.6 5.0 3.3 2 2 1 3 3 3 0 Triose-phosphate Transporter family Ferrochelatase PF00762.14 EPY50068.1 - 3.8e-95 318.4 0.0 4.5e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase F_bP_aldolase PF01116.15 EPY50068.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II SRP72 PF08492.7 EPY50069.1 - 3e-12 46.7 3.7 3e-12 46.7 2.6 1.9 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_11 PF13414.1 EPY50069.1 - 0.0016 18.0 3.6 1.6 8.4 0.0 3.7 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 EPY50069.1 - 0.0035 17.8 0.7 65 4.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPY50069.1 - 0.004 16.8 1.3 3 7.8 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPY50069.1 - 0.018 15.4 4.6 3.3 8.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPY50069.1 - 0.076 13.7 1.9 6.2 7.6 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat bZIP_2 PF07716.10 EPY50069.1 - 0.11 12.2 4.1 0.35 10.7 2.8 1.8 1 0 0 1 1 1 0 Basic region leucine zipper TPR_2 PF07719.12 EPY50069.1 - 0.15 12.0 5.9 3.3 7.8 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50069.1 - 0.2 11.6 3.0 7.3 6.6 0.3 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat UPF0113 PF03657.8 EPY50070.1 - 8.1e-10 38.5 0.0 9.6e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PTPA PF03095.10 EPY50070.1 - 0.071 12.2 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein PUA PF01472.15 EPY50070.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 PUA domain EVC2_like PF12297.3 EPY50071.1 - 0.006 15.2 0.3 0.013 14.1 0.1 1.6 2 0 0 2 2 2 1 Ellis van Creveld protein 2 like protein Formyl_trans_N PF00551.14 EPY50071.1 - 0.02 14.4 0.7 0.59 9.6 0.3 2.5 3 0 0 3 3 3 0 Formyl transferase ApoC-I PF04691.7 EPY50071.1 - 0.039 13.6 0.5 0.097 12.3 0.4 1.7 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Cortex-I_coil PF09304.5 EPY50071.1 - 0.086 12.8 2.0 0.16 11.9 1.4 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Peptidase_M76 PF09768.4 EPY50073.1 - 5.3e-65 218.0 2.2 6.1e-65 217.8 1.5 1.0 1 0 0 1 1 1 1 Peptidase M76 family DUF2268 PF10026.4 EPY50073.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.4 EPY50073.1 - 0.42 10.2 5.6 0.99 9.0 3.7 2.0 1 1 0 1 1 1 0 SprT-like family Pkinase PF00069.20 EPY50074.1 - 1e-73 247.7 0.0 1.2e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50074.1 - 5.1e-48 163.3 0.0 6.5e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50074.1 - 6.1e-10 38.5 0.0 6e-09 35.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPY50074.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPY50074.1 - 0.019 14.3 0.2 0.042 13.1 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EPY50074.1 - 0.096 12.3 0.6 0.71 9.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L24e PF01246.15 EPY50075.1 - 7.8e-31 105.7 0.2 7.8e-31 105.7 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e ATP-synt_E PF05680.7 EPY50075.1 - 2.2 8.3 9.8 13 5.8 6.8 2.0 1 1 0 1 1 1 0 ATP synthase E chain Sin_N PF04801.8 EPY50076.1 - 1.9e-28 99.5 0.5 2.2e-28 99.2 0.3 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region Sdh_cyt PF01127.17 EPY50077.1 - 1.4e-26 92.7 1.3 1.8e-26 92.3 0.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit RCC1 PF00415.13 EPY50078.1 - 1.1e-25 89.6 0.1 4.2e-08 33.2 0.0 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EPY50078.1 - 5.1e-22 77.9 4.6 4.5e-13 49.1 0.0 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 EPY50078.1 - 1.2e-10 41.2 0.1 6e-05 23.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPY50078.1 - 1.5e-09 38.0 0.1 4.4e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPY50078.1 - 3.7e-09 36.8 1.2 9.3e-08 32.3 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EPY50078.1 - 2.4e-08 33.3 0.1 0.011 15.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.1 EPY50078.1 - 2.9e-08 33.1 5.4 3e-06 26.6 0.5 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EPY50078.1 - 4.6e-08 32.5 0.5 0.013 15.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Pox_MCEL PF03291.11 EPY50079.1 - 9.9e-97 323.7 0.0 1.3e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.1 EPY50079.1 - 7.2e-12 45.5 0.0 2.1e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY50079.1 - 1.1e-09 38.0 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY50079.1 - 1.1e-09 38.7 0.0 2.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY50079.1 - 2.6e-09 36.9 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY50079.1 - 4.4e-09 36.7 0.0 8.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY50079.1 - 1.2e-08 35.2 0.0 2.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY50079.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPY50079.1 - 0.0032 16.5 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.5 EPY50079.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NUC153 PF08159.7 EPY50080.1 - 2.3e-08 33.4 3.7 5.1e-08 32.3 2.5 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EPY50080.1 - 0.0063 16.3 0.1 2.6 8.0 0.0 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Epimerase PF01370.16 EPY50081.1 - 5.6e-15 55.4 0.0 8.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPY50081.1 - 6.7e-14 52.2 0.3 1.5e-13 51.1 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPY50081.1 - 6.5e-10 38.1 0.1 1.2e-07 30.7 0.2 2.3 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPY50081.1 - 2e-08 33.7 0.6 6.7e-08 32.0 0.2 2.0 2 1 1 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.7 EPY50081.1 - 2.7e-07 29.7 0.2 0.00014 20.8 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EPY50081.1 - 3.9e-07 29.2 0.0 7.1e-07 28.3 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EPY50081.1 - 2.3e-05 24.3 1.5 0.00016 21.5 1.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 EPY50081.1 - 6.5e-05 22.8 0.3 0.00018 21.4 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EPY50081.1 - 8.5e-05 22.9 0.2 0.00017 21.9 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EPY50081.1 - 0.00014 20.9 0.0 0.0025 16.7 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EPY50081.1 - 0.0053 17.0 0.6 0.022 15.0 0.1 2.2 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EPY50081.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 EPY50081.1 - 0.037 13.6 0.6 0.2 11.2 0.4 2.0 1 1 0 1 1 1 0 KR domain DFP PF04127.10 EPY50081.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.13 EPY50081.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MBOAT PF03062.14 EPY50082.1 - 2.4e-30 105.7 26.2 2.4e-30 105.7 18.2 1.7 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPY50082.1 - 0.00011 22.2 2.8 0.00011 22.2 2.0 2.8 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Pal1 PF08316.6 EPY50083.1 - 1.1e-35 123.1 3.8 1.5e-33 116.2 2.6 2.7 1 1 0 1 1 1 1 Pal1 cell morphology protein CENP-B_N PF04218.8 EPY50083.1 - 0.067 12.6 0.1 0.22 10.9 0.1 1.9 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Arrestin_C PF02752.17 EPY50084.1 - 4.9e-13 49.3 2.6 1.2e-12 48.1 1.8 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.20 EPY50085.1 - 3.3e-35 121.4 0.0 5.3e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50085.1 - 5.2e-27 94.5 0.0 7.7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50085.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPY50085.1 - 0.24 11.0 0.0 0.66 9.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family EXS PF03124.9 EPY50086.1 - 4.1e-59 200.3 30.4 2.9e-47 161.3 10.5 2.2 2 0 0 2 2 2 2 EXS family SPX PF03105.14 EPY50086.1 - 2.6e-11 43.8 2.2 2.6e-11 43.8 1.5 1.5 2 0 0 2 2 2 1 SPX domain Semialdhyde_dhC PF02774.13 EPY50087.1 - 5e-45 153.6 0.0 1e-44 152.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EPY50087.1 - 2.1e-32 111.9 0.0 4.9e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EPY50087.1 - 5.5e-05 23.7 0.0 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 EPY50087.1 - 0.0014 17.6 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EPY50087.1 - 0.025 14.4 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 EPY50087.1 - 0.08 12.3 0.1 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain RRM_1 PF00076.17 EPY50088.1 - 1.8e-11 43.4 0.1 5.2e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50088.1 - 1.9e-10 40.4 0.6 3.8e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50088.1 - 8.2e-09 35.3 0.3 6.3e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 EPY50089.1 - 5.3e-08 33.1 0.1 1.1e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPY50089.1 - 2.1e-07 30.9 0.1 8e-07 29.1 0.0 2.0 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EPY50089.1 - 1.3e-06 27.9 0.1 5.1e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EPY50089.1 - 3.3e-05 24.2 0.0 0.00036 20.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPY50089.1 - 0.0017 18.3 0.1 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat DUF971 PF06155.7 EPY50089.1 - 0.061 13.7 0.1 0.22 11.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF971) adh_short PF00106.20 EPY50090.1 - 9.7e-28 97.1 0.4 1.3e-27 96.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY50090.1 - 3e-20 73.0 0.2 3.8e-20 72.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY50090.1 - 5.2e-08 32.7 0.3 8e-08 32.1 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY50090.1 - 2.6e-06 27.5 0.3 3.3e-06 27.2 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EPY50090.1 - 0.00021 20.5 0.0 0.0013 17.9 0.0 1.9 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EPY50090.1 - 0.0022 17.4 0.1 0.0069 15.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPY50090.1 - 0.0084 15.8 0.1 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPY50090.1 - 0.016 14.3 0.4 0.37 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DLH PF01738.13 EPY50091.1 - 1.3e-15 57.2 0.0 1.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPY50091.1 - 8.2e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Viral_cys_rich PF08008.7 EPY50091.1 - 0.099 12.2 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Viral cysteine rich AMP-binding PF00501.23 EPY50092.1 - 6.3e-88 294.9 0.0 8.3e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPY50092.1 - 1.3e-15 58.0 0.2 3.9e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EPY50092.1 - 0.0012 17.4 0.1 0.0066 15.0 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter DUF1128 PF06569.6 EPY50092.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) CTP_transf_2 PF01467.21 EPY50093.1 - 5.9e-23 81.6 1.5 1.8e-22 80.1 0.0 2.4 3 0 0 3 3 3 1 Cytidylyltransferase CagX PF03524.10 EPY50093.1 - 0.012 14.9 0.2 0.018 14.3 0.2 1.4 1 0 0 1 1 1 0 Conjugal transfer protein DUF1253 PF06862.7 EPY50094.1 - 5.4e-164 545.8 4.1 8.9e-164 545.0 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) F-box-like PF12937.2 EPY50095.1 - 2.3e-05 24.0 4.2 2.6e-05 23.8 0.5 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPY50095.1 - 0.026 14.1 0.5 0.061 13.0 0.4 1.7 1 0 0 1 1 1 0 F-box domain TMEM171 PF15471.1 EPY50096.1 - 0.11 11.3 2.4 0.11 11.2 1.7 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF2406 PF10295.4 EPY50097.1 - 6.5e-17 61.8 0.1 2.4e-16 59.9 0.1 2.0 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Methyltransf_11 PF08241.7 EPY50098.1 - 4.7e-19 68.6 0.0 1e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY50098.1 - 8.8e-17 61.0 0.0 1.4e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY50098.1 - 5.1e-15 55.5 0.0 1e-14 54.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY50098.1 - 1.8e-13 50.8 0.0 6.5e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY50098.1 - 1.7e-11 44.6 0.0 3.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY50098.1 - 4.3e-11 43.0 0.0 8.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EPY50098.1 - 1.4e-08 34.1 0.0 2.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EPY50098.1 - 2.5e-08 33.4 0.0 4.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EPY50098.1 - 4e-08 32.6 0.1 2.2e-07 30.2 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EPY50098.1 - 9.9e-08 31.5 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EPY50098.1 - 4.9e-07 29.8 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EPY50098.1 - 1.5e-06 26.8 0.0 2.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.15 EPY50098.1 - 4.6e-06 25.8 0.0 1.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EPY50098.1 - 0.00013 21.7 0.1 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EPY50098.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.7 EPY50098.1 - 0.00054 18.9 0.0 0.0015 17.4 0.0 1.8 1 1 1 2 2 2 1 DREV methyltransferase DOT1 PF08123.8 EPY50098.1 - 0.00083 18.7 0.1 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 TPMT PF05724.6 EPY50098.1 - 0.0014 18.1 0.0 0.004 16.6 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.6 EPY50098.1 - 0.0022 16.7 0.0 0.003 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 EPY50098.1 - 0.0023 17.0 0.0 0.0037 16.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EPY50098.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EPY50098.1 - 0.022 13.7 0.0 0.051 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase N6_N4_Mtase PF01555.13 EPY50098.1 - 0.027 13.9 0.0 0.097 12.1 0.0 1.8 2 0 0 2 2 2 0 DNA methylase Methyltransf_5 PF01795.14 EPY50098.1 - 0.034 13.4 0.0 0.091 12.0 0.0 1.9 1 1 0 1 1 1 0 MraW methylase family Pox_MCEL PF03291.11 EPY50098.1 - 0.037 12.8 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme Thymidylate_kin PF02223.12 EPY50099.1 - 5.8e-51 172.5 0.1 6.6e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 EPY50099.1 - 0.00015 22.0 1.0 0.004 17.4 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPY50099.1 - 0.0008 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY50099.1 - 0.00082 19.2 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPY50099.1 - 0.00099 19.0 0.7 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPY50099.1 - 0.0032 17.2 0.3 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_35 PF14516.1 EPY50099.1 - 0.004 15.8 0.1 0.0055 15.3 0.1 1.2 1 0 0 1 1 1 1 AAA-like domain KTI12 PF08433.5 EPY50099.1 - 0.01 15.0 0.2 0.028 13.6 0.0 1.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 MobB PF03205.9 EPY50099.1 - 0.019 14.6 0.1 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EPY50099.1 - 0.02 14.9 0.0 0.035 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EPY50099.1 - 0.021 14.9 0.1 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 EPY50099.1 - 0.041 13.2 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTS_2 PF15448.1 EPY50099.1 - 0.054 13.8 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein ThiI PF02568.9 EPY50099.1 - 0.068 12.6 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ADK PF00406.17 EPY50099.1 - 0.083 12.7 0.1 0.24 11.2 0.0 2.1 1 1 0 1 1 1 0 Adenylate kinase Eno-Rase_FAD_bd PF07055.7 EPY50099.1 - 0.13 12.2 0.2 23 5.0 0.0 2.9 2 1 1 3 3 3 0 Enoyl reductase FAD binding domain SAC3_GANP PF03399.11 EPY50100.1 - 3.8e-51 173.5 0.2 5.1e-51 173.1 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPY50100.1 - 2.5e-07 30.5 0.0 1.2e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 NHS PF15273.1 EPY50100.1 - 0.057 12.0 1.1 0.078 11.5 0.7 1.2 1 0 0 1 1 1 0 NHS-like Pkinase PF00069.20 EPY50101.1 - 1.1e-48 165.6 0.0 1.7e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50101.1 - 3.1e-30 105.1 0.0 4.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPY50101.1 - 0.0017 17.4 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY50101.1 - 0.0027 16.7 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPY50101.1 - 0.071 12.4 0.0 0.51 9.6 0.0 2.2 3 0 0 3 3 3 0 RIO1 family TFIID-18kDa PF02269.11 EPY50102.1 - 1.1e-26 92.4 0.3 1.3e-26 92.2 0.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EPY50102.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EPY50102.1 - 0.072 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY50102.1 - 0.089 12.8 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UNC45-central PF11701.3 EPY50103.1 - 0.0019 17.8 0.6 0.37 10.4 0.0 3.1 2 1 1 3 3 3 2 Myosin-binding striated muscle assembly central RYDR_ITPR PF01365.16 EPY50103.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.6 1 0 0 1 1 1 0 RIH domain PDH PF02153.12 EPY50104.1 - 1.4e-13 50.3 0.0 1.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EPY50104.1 - 1.6e-05 25.2 0.0 4.4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EPY50104.1 - 3.8e-05 23.5 0.0 6.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EPY50104.1 - 0.00051 19.2 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EPY50104.1 - 0.00063 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EPY50104.1 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPY50104.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 EPY50104.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EPY50104.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UCH PF00443.24 EPY50105.1 - 6.7e-90 300.8 0.0 2.5e-89 298.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY50105.1 - 1.7e-24 86.7 0.2 2.5e-13 50.1 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EPY50105.1 - 5.9e-13 49.0 3.2 8.1e-13 48.6 0.1 2.9 3 0 0 3 3 3 1 DUSP domain Zn-ribbon_8 PF09723.5 EPY50105.1 - 0.05 13.5 1.7 1.6 8.7 0.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain UN_NPL4 PF11543.3 EPY50105.1 - 0.13 12.5 0.2 2.8 8.3 0.0 3.0 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 DEAD PF00270.24 EPY50106.1 - 6.9e-40 136.2 0.2 1.3e-39 135.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY50106.1 - 5.9e-22 77.3 0.0 7.6e-12 44.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EPY50106.1 - 0.0002 21.2 5.5 0.00064 19.6 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RNase_H2-Ydr279 PF09468.5 EPY50106.1 - 0.41 9.7 11.8 0.0093 15.2 2.5 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DUF2428 PF10350.4 EPY50107.1 - 1.7e-69 233.7 0.0 3e-69 232.8 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_EZ PF13513.1 EPY50107.1 - 0.091 13.2 1.8 1.8 9.1 0.1 3.7 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 EPY50107.1 - 0.85 9.8 9.7 8.4 6.7 0.0 6.1 7 0 0 7 7 7 0 HEAT repeat NT-C2 PF10358.4 EPY50108.1 - 4.5e-24 84.5 0.0 6.2e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF1221 PF06760.6 EPY50109.1 - 0.013 14.7 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Pro_dh PF01619.13 EPY50111.1 - 1.4e-44 152.3 0.0 3e-44 151.2 0.0 1.5 1 1 0 1 1 1 1 Proline dehydrogenase Acetyltransf_1 PF00583.19 EPY50112.1 - 1.6e-07 31.2 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY50112.1 - 3.7e-07 30.1 0.0 6.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY50112.1 - 5.8e-06 26.1 0.0 4e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPY50112.1 - 0.014 15.4 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPY50112.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IATP PF04568.7 EPY50114.1 - 3.8e-12 46.1 0.3 4e-12 46.0 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Bap31 PF05529.7 EPY50114.1 - 0.049 13.0 0.4 0.053 12.9 0.3 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4279 PF14106.1 EPY50114.1 - 0.16 11.8 1.2 0.27 11.1 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) PspB PF06667.7 EPY50114.1 - 0.23 11.4 2.0 0.34 10.8 1.4 1.2 1 0 0 1 1 1 0 Phage shock protein B Phlebovirus_NSM PF07246.6 EPY50114.1 - 0.23 10.5 1.8 0.25 10.4 1.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Myc-LZ PF02344.10 EPY50114.1 - 0.39 10.3 4.7 0.76 9.4 3.3 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain LisH PF08513.6 EPY50115.1 - 1.3e-09 37.5 0.6 3.6e-09 36.0 0.4 1.9 1 0 0 1 1 1 1 LisH EURL PF06937.6 EPY50115.1 - 0.055 12.8 4.2 0.14 11.5 2.9 1.7 1 0 0 1 1 1 0 EURL protein FAD_binding_6 PF00970.19 EPY50116.1 - 4.5e-11 42.7 0.0 8.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPY50116.1 - 2.9e-09 37.4 0.0 6.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EPY50116.1 - 6e-09 36.2 0.0 3.3e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 Globin NAD_binding_6 PF08030.7 EPY50116.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Nuc_N PF14448.1 EPY50116.1 - 0.01 15.3 0.0 0.27 10.8 0.0 2.4 2 0 0 2 2 2 0 Nuclease N terminal Protoglobin PF11563.3 EPY50116.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protoglobin MUG2_C PF08593.5 EPY50117.1 - 1.4e-14 54.0 0.0 3.8e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal DUF4030 PF13222.1 EPY50117.1 - 0.012 15.2 0.5 0.018 14.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) DAP_B PF07930.7 EPY50117.1 - 0.074 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B YvrJ PF12841.2 EPY50117.1 - 0.27 10.5 2.0 1.6 8.0 0.1 2.8 2 1 1 3 3 3 0 YvrJ protein family Vps51 PF08700.6 EPY50117.1 - 0.47 10.3 2.5 0.58 10.0 0.1 2.1 2 0 0 2 2 2 0 Vps51/Vps67 HSBP1 PF06825.7 EPY50117.1 - 5.2 6.7 7.1 26 4.4 4.9 2.1 1 1 0 1 1 1 0 Heat shock factor binding protein 1 adh_short_C2 PF13561.1 EPY50118.1 - 2.4e-34 119.1 0.0 2.9e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPY50118.1 - 4.6e-34 117.7 0.1 6.1e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY50118.1 - 9e-13 48.2 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY50118.1 - 2e-06 27.9 0.6 3.4e-06 27.1 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY50118.1 - 0.0015 18.0 0.4 0.0024 17.3 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPY50118.1 - 0.024 13.6 0.1 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EPY50118.1 - 0.076 12.8 0.3 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EPY50118.1 - 0.13 11.9 0.6 0.2 11.2 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 EPY50118.1 - 0.2 11.2 2.6 0.87 9.1 0.6 2.7 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.20 EPY50119.1 - 4.4e-34 117.8 0.1 5.4e-34 117.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY50119.1 - 1.2e-29 103.7 0.0 1.5e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY50119.1 - 1.6e-14 53.9 0.0 2.3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPY50119.1 - 3e-06 26.6 0.0 4.6e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EPY50119.1 - 0.00035 20.6 0.5 0.00064 19.7 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY50119.1 - 0.0014 18.1 0.4 0.0022 17.5 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPY50119.1 - 0.059 13.1 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 EPY50119.1 - 0.075 11.9 0.1 0.17 10.7 0.1 1.6 2 0 0 2 2 2 0 Male sterility protein THF_DHG_CYH_C PF02882.14 EPY50119.1 - 0.082 11.9 0.1 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EPY50119.1 - 0.12 12.0 0.7 0.2 11.3 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EPY50120.1 - 2.3e-25 89.4 0.0 2.9e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY50120.1 - 7.2e-25 88.1 0.0 9e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY50120.1 - 1.5e-08 34.4 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPY50120.1 - 0.029 14.1 0.2 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPY50120.1 - 0.039 13.0 0.1 0.07 12.2 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EPY50120.1 - 0.11 11.8 0.1 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPY50120.1 - 0.12 12.3 0.5 0.23 11.4 0.4 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EPY50122.1 - 1.5e-10 40.9 0.1 3e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPY50122.1 - 6.2e-10 38.7 0.0 9.3e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPY50122.1 - 3.5e-08 33.6 0.0 5.3e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPY50122.1 - 3.6e-05 22.6 0.0 0.007 15.1 0.0 2.3 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EPY50122.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EPY50122.1 - 0.0038 16.6 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 EPY50122.1 - 0.0068 15.3 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 EPY50122.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF3682 PF12446.3 EPY50123.1 - 0.11 12.7 5.1 0.15 12.3 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Sugar_tr PF00083.19 EPY50124.1 - 1.9e-21 76.1 35.6 1.3e-19 70.1 24.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY50124.1 - 6.2e-18 64.6 33.2 6.2e-18 64.6 23.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AbiH PF14253.1 EPY50125.1 - 0.07 12.7 0.5 0.079 12.5 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH GST_C PF00043.20 EPY50126.1 - 3.4e-23 81.4 1.0 4.3e-11 42.6 0.0 2.7 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPY50126.1 - 5.6e-14 51.7 1.4 1e-05 25.3 0.0 3.3 4 0 0 4 4 4 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY50126.1 - 1.7e-08 34.8 0.2 0.0043 17.5 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPY50126.1 - 9.4e-08 31.9 0.0 3e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPY50126.1 - 1.5e-06 28.3 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPY50126.1 - 1.6e-06 28.1 0.0 4.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3406 PF11886.3 EPY50126.1 - 0.00027 19.8 0.0 0.63 8.8 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3406) DUF4172 PF13776.1 EPY50126.1 - 0.00073 19.5 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4172) DOCK-C2 PF14429.1 EPY50126.1 - 0.059 12.9 1.2 6.7 6.2 0.2 2.2 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Nitrate_red_del PF02613.10 EPY50127.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase delta subunit 2CSK_N PF08521.5 EPY50127.1 - 0.12 11.9 0.2 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal CaKB PF03185.10 EPY50128.1 - 0.14 11.4 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit FA_desaturase PF00487.19 EPY50128.1 - 1 8.7 6.9 0.3 10.4 2.9 1.6 2 0 0 2 2 2 0 Fatty acid desaturase DUF2207 PF09972.4 EPY50128.1 - 1.6 7.1 3.8 2.2 6.7 2.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MUG2_C PF08593.5 EPY50129.1 - 4.2e-09 36.4 1.0 1.1e-08 35.1 0.7 1.7 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal MUG2_C PF08593.5 EPY50131.1 - 3.4e-05 23.9 0.2 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal Peptidase_C15 PF01470.12 EPY50131.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyroglutamyl peptidase MFS_1 PF07690.11 EPY50132.1 - 1e-44 152.7 25.3 1.3e-44 152.3 17.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY50132.1 - 3.2e-10 39.2 19.6 5.7e-08 31.7 8.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EPY50132.1 - 0.00022 19.4 2.8 0.00028 19.0 0.1 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EPY50132.1 - 0.026 14.5 2.0 0.13 12.3 1.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) NAD_binding_10 PF13460.1 EPY50133.1 - 2.5e-23 83.0 0.0 3.2e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY50133.1 - 3.4e-06 26.6 0.0 4.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPY50133.1 - 0.0037 16.5 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EPY50133.1 - 0.0071 15.3 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Arginase PF00491.16 EPY50134.1 - 1.5e-89 300.0 0.0 1.9e-89 299.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPY50134.1 - 0.0022 18.2 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain MFS_1 PF07690.11 EPY50135.1 - 8.1e-26 90.5 42.2 8.1e-26 90.5 29.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY50135.1 - 4.1e-07 28.9 38.2 1.8e-06 26.8 26.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TauD PF02668.11 EPY50136.1 - 7.6e-46 156.8 0.5 9.9e-46 156.4 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lipid_DES PF08557.5 EPY50136.1 - 0.053 12.7 0.3 0.12 11.5 0.2 1.6 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) OPT PF03169.10 EPY50137.1 - 1.1e-194 648.4 45.7 1.2e-194 648.2 31.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TPP_enzyme_N PF02776.13 EPY50138.1 - 7.4e-40 136.2 0.3 3.6e-37 127.4 0.2 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPY50138.1 - 1.6e-24 86.2 4.3 2.9e-23 82.1 0.0 3.2 4 0 0 4 4 4 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPY50138.1 - 8.7e-20 70.8 0.0 3.1e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EPY50138.1 - 0.00029 20.4 0.0 0.00079 19.0 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit XH PF03469.9 EPY50138.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 XH domain Glyco_transf_34 PF05637.7 EPY50139.1 - 6.4e-74 248.4 0.4 7.7e-74 248.1 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EPY50139.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF3808 PF10300.4 EPY50140.1 - 4.5e-75 253.0 5.1 5.4e-75 252.7 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) PhzC-PhzF PF02567.11 EPY50141.1 - 3.4e-60 203.6 0.0 3.8e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 EPY50141.1 - 5.1e-06 25.5 0.0 7.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Proline racemase CDKN3 PF05706.7 EPY50141.1 - 0.0065 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) HTH_psq PF05225.11 EPY50142.1 - 0.063 12.8 0.1 0.063 12.8 0.0 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain YyzF PF14116.1 EPY50142.1 - 0.43 10.5 2.1 6.8 6.7 0.1 2.4 2 1 1 3 3 3 0 YyzF-like protein Aldedh PF00171.17 EPY50143.1 - 9.6e-10 37.3 0.1 1.4e-06 26.8 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family FBPase PF00316.15 EPY50144.1 - 1.7e-120 401.7 0.0 1.9e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EPY50144.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family Abhydrolase_3 PF07859.8 EPY50145.1 - 4.5e-54 183.2 0.0 5.5e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPY50145.1 - 1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EPY50145.1 - 3.9e-05 22.4 0.0 5.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EPY50145.1 - 0.00033 19.5 0.7 0.053 12.2 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.16 EPY50145.1 - 0.019 14.2 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family SPC25 PF06703.6 EPY50146.1 - 0.02 14.4 0.3 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) AA_permease PF00324.16 EPY50147.1 - 3.2e-123 411.5 48.9 3.9e-123 411.3 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY50147.1 - 4.3e-30 104.6 51.7 5.6e-30 104.2 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3165 PF11364.3 EPY50147.1 - 5.1 7.2 11.2 9.6 6.4 1.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3165) Fungal_trans PF04082.13 EPY50148.1 - 1.5e-22 79.7 1.5 2.7e-22 78.8 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY50148.1 - 4.5e-09 36.0 10.0 1.1e-08 34.8 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EPY50149.1 - 4.6e-28 96.6 0.0 5.4e-10 38.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50149.1 - 4e-20 71.5 0.0 1.5e-06 28.0 0.0 3.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50149.1 - 2.9e-08 33.4 0.0 0.022 14.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPY50149.1 - 2.6e-06 27.0 0.0 0.0003 20.4 0.0 2.6 3 0 0 3 3 3 1 Limkain b1 Calcipressin PF04847.7 EPY50149.1 - 0.00055 19.5 0.0 0.0037 16.8 0.0 2.0 2 0 0 2 2 2 1 Calcipressin RRM_3 PF08777.6 EPY50149.1 - 0.027 14.3 0.0 1.9 8.3 0.0 2.8 2 1 1 3 3 3 0 RNA binding motif DUF968 PF06147.6 EPY50149.1 - 0.06 13.2 0.0 0.097 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF968) Ribonuc_red_sm PF00268.16 EPY50149.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain DUF4596 PF15363.1 EPY50149.1 - 0.33 10.8 1.9 0.42 10.5 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) WD40 PF00400.27 EPY50150.1 - 4.8e-41 137.1 4.6 5.5e-08 32.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPY50150.1 - 0.00081 17.6 1.5 0.015 13.4 1.1 2.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Gmad1 PF10647.4 EPY50150.1 - 0.059 12.7 0.1 1.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF1082 PF06449.6 EPY50150.1 - 0.72 9.7 3.2 15 5.5 0.0 3.0 1 1 1 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) LisH PF08513.6 EPY50151.1 - 1.8e-10 40.1 0.5 3.9e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 LisH Ndc80_HEC PF03801.8 EPY50151.1 - 0.012 15.1 2.6 0.013 14.9 0.3 2.3 2 0 0 2 2 2 0 HEC/Ndc80p family Cyt-b5 PF00173.23 EPY50152.1 - 4.3e-22 77.7 0.0 5.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TIM21 PF08294.6 EPY50153.1 - 2.6e-36 124.4 0.0 3.3e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 UDPGP PF01704.13 EPY50154.1 - 4.6e-41 140.7 0.0 6e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EPY50154.1 - 0.034 14.2 0.1 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain RNA_pol_A_bac PF01000.21 EPY50155.1 - 1.2e-28 99.4 0.0 2.7e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPY50155.1 - 6.3e-13 47.6 0.0 8.7e-13 47.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain V-ATPase_G PF03179.10 EPY50157.1 - 7.2e-30 103.3 15.1 8.1e-30 103.2 10.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Nop25 PF09805.4 EPY50157.1 - 0.0018 18.3 12.6 0.0023 18.0 8.8 1.1 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) ATP-synt_B PF00430.13 EPY50157.1 - 0.091 12.5 18.3 0.25 11.1 9.3 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) AIP3 PF03915.8 EPY50157.1 - 0.11 11.4 8.6 0.11 11.3 5.9 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF2870 PF11069.3 EPY50157.1 - 0.14 12.2 3.4 0.18 11.8 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) GA PF01468.12 EPY50157.1 - 0.23 11.6 0.2 0.23 11.6 0.1 2.3 3 0 0 3 3 3 0 GA module DUF3552 PF12072.3 EPY50157.1 - 0.36 10.0 17.5 0.13 11.4 6.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Prominin PF05478.6 EPY50157.1 - 0.41 8.1 4.5 0.46 7.9 3.1 1.0 1 0 0 1 1 1 0 Prominin HSP70 PF00012.15 EPY50157.1 - 0.46 8.3 9.4 0.54 8.1 6.5 1.0 1 0 0 1 1 1 0 Hsp70 protein Atg14 PF10186.4 EPY50157.1 - 0.48 9.3 9.7 0.53 9.1 6.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2252 PF10009.4 EPY50157.1 - 0.68 8.7 4.5 0.74 8.6 3.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF883 PF05957.8 EPY50157.1 - 0.98 9.8 8.2 7.8 6.9 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) SAM_2 PF07647.12 EPY50158.1 - 2.5e-15 56.0 0.0 5.4e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EPY50158.1 - 4.3e-11 43.0 0.1 2.1e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EPY50158.1 - 1.8e-10 40.9 0.0 1e-09 38.5 0.0 2.3 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 EPY50158.1 - 3.9e-10 38.9 0.1 9.6e-10 37.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SAM_1 PF00536.25 EPY50158.1 - 1.4e-09 37.9 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EPY50158.1 - 1.3e-08 34.2 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 EPY50158.1 - 0.0017 18.3 0.1 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 EPY50158.1 - 0.0032 16.9 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain S_layer_C PF05124.7 EPY50158.1 - 0.1 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 S-layer like family, C-terminal region IspD PF01128.14 EPY50158.1 - 0.25 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ras PF00071.17 EPY50159.1 - 1.2e-47 161.3 0.0 1.4e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY50159.1 - 9.1e-15 55.2 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY50159.1 - 8.4e-11 41.4 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY50159.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EPY50159.1 - 0.00023 21.3 0.1 0.0018 18.4 0.0 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EPY50159.1 - 0.023 13.3 1.7 0.97 8.0 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EPY50159.1 - 0.027 13.7 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EPY50159.1 - 0.047 13.8 0.1 0.26 11.4 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPY50159.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPY50159.1 - 0.16 11.0 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 KaiC RRM_6 PF14259.1 EPY50160.1 - 1.2e-14 53.9 0.1 2.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY50160.1 - 2.1e-11 43.2 1.4 0.00029 20.4 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50160.1 - 6.3e-07 29.1 0.1 4.5e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1985 PF09331.6 EPY50160.1 - 0.11 12.3 1.9 1.2 8.9 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1985) GIDA PF01134.17 EPY50160.1 - 0.31 9.8 4.3 0.13 11.1 0.2 1.9 1 1 0 2 2 2 0 Glucose inhibited division protein A DUF755 PF05501.6 EPY50160.1 - 7.6 6.6 19.8 0.46 10.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Sel1 PF08238.7 EPY50161.1 - 1.9e-20 72.8 15.5 0.00079 19.9 0.1 7.4 7 0 0 7 7 7 5 Sel1 repeat TPR_8 PF13181.1 EPY50161.1 - 5.6e-06 25.7 1.0 0.017 14.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY50161.1 - 1e-05 25.0 4.1 0.017 14.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY50161.1 - 9.3e-05 21.8 8.7 0.0061 16.1 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50161.1 - 0.0035 17.2 6.9 0.031 14.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPY50161.1 - 0.0081 16.5 2.1 2.9 8.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPY50161.1 - 0.018 14.7 7.5 1.5 8.5 0.2 4.1 3 1 0 3 3 3 0 TPR repeat TPR_17 PF13431.1 EPY50161.1 - 0.018 15.2 1.7 4.6 7.6 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPY50161.1 - 0.28 11.0 0.1 0.28 11.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPY50161.1 - 0.33 11.6 12.3 1.7 9.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop16 PF09420.5 EPY50162.1 - 2.6e-40 138.1 7.5 3.2e-40 137.9 5.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 WD40 PF00400.27 EPY50163.1 - 1.3e-07 31.2 8.0 0.44 10.5 0.0 6.0 5 1 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPY50163.1 - 0.022 14.5 0.0 1.3 8.8 0.0 3.0 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EPY50163.1 - 0.041 13.5 0.1 2.7 7.6 0.0 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A 2Fe-2S_thioredx PF01257.14 EPY50164.1 - 1.1e-23 83.3 0.0 1.6e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Homeobox PF00046.24 EPY50164.1 - 0.065 12.8 0.0 8.5 6.0 0.0 2.6 2 0 0 2 2 2 0 Homeobox domain Glyco_hydro_72 PF03198.9 EPY50165.1 - 2.8e-138 460.1 4.5 3.4e-138 459.8 3.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EPY50165.1 - 0.00011 21.5 0.5 0.00059 19.1 0.3 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Sec7 PF01369.15 EPY50166.1 - 5.1e-36 124.1 1.6 1.2e-35 122.9 1.1 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EPY50166.1 - 5.5e-10 39.4 0.0 1.8e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Reprolysin_4 PF13583.1 EPY50166.1 - 0.017 14.6 0.2 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like VanZ PF04892.7 EPY50167.1 - 1.3e-17 63.9 8.2 2.6e-17 63.0 5.7 1.5 1 1 0 1 1 1 1 VanZ like family TauE PF01925.14 EPY50167.1 - 0.083 12.3 6.2 0.2 11.0 3.5 1.7 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Y_phosphatase PF00102.22 EPY50168.1 - 5.7e-61 205.8 0.9 7.2e-61 205.5 0.6 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPY50168.1 - 4.3e-06 26.8 0.0 7.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EPY50168.1 - 2.6e-05 24.5 0.0 5.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EPY50168.1 - 0.0009 18.8 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EPY50168.1 - 0.0023 16.7 0.0 0.0038 16.0 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Nse5 PF08691.5 EPY50169.1 - 1.5e-12 46.8 22.0 2.9e-08 32.6 6.6 2.1 2 0 0 2 2 2 2 DNA repair proteins Nse5 and Nse6 vATP-synt_E PF01991.13 EPY50170.1 - 1.6e-58 197.2 10.5 1.9e-58 197.0 7.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TF_AP-2 PF03299.9 EPY50170.1 - 0.0045 16.5 1.4 0.0077 15.8 1.0 1.4 1 0 0 1 1 1 1 Transcription factor AP-2 SRF-TF PF00319.13 EPY50171.1 - 2.6e-17 61.7 0.0 5e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) WD40 PF00400.27 EPY50172.1 - 1.1e-10 40.9 16.9 6.1e-05 22.7 0.4 5.8 6 1 0 6 6 6 4 WD domain, G-beta repeat RWD PF05773.17 EPY50172.1 - 0.0026 17.6 0.0 0.036 13.9 0.0 2.5 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.1 EPY50172.1 - 3.9 7.3 11.8 0.51 10.2 5.1 1.9 2 0 0 2 2 2 0 Ring finger domain UQ_con PF00179.21 EPY50173.1 - 5.9e-47 158.6 0.0 6.7e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPY50173.1 - 0.00019 21.1 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EPY50173.1 - 0.0073 15.9 0.1 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EPY50173.1 - 0.0075 16.1 0.1 0.013 15.3 0.1 1.7 1 1 0 1 1 1 1 RWD domain Csm1 PF12539.3 EPY50174.1 - 1.1e-14 54.6 0.6 3e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF3186 PF11382.3 EPY50174.1 - 0.086 11.9 2.4 0.15 11.1 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DUF2315 PF10231.4 EPY50174.1 - 0.13 12.1 4.5 0.35 10.7 3.1 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) UPF0242 PF06785.6 EPY50174.1 - 0.7 8.5 8.6 0.89 8.1 6.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Nnf1 PF03980.9 EPY50174.1 - 0.75 9.8 17.2 0.68 9.9 3.5 2.5 1 1 1 2 2 2 0 Nnf1 ALMT PF11744.3 EPY50174.1 - 0.81 8.2 3.1 1.2 7.7 2.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DMPK_coil PF08826.5 EPY50174.1 - 0.92 9.4 11.9 0.051 13.4 2.7 2.9 2 1 1 3 3 3 0 DMPK coiled coil domain like SpoIIIAH PF12685.2 EPY50174.1 - 1.5 8.2 11.1 2.2 7.7 7.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Membr_traf_MHD PF10540.4 EPY50175.1 - 3e-26 91.8 0.0 1.1e-25 90.0 0.0 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EPY50175.1 - 2.7e-05 23.8 0.0 7.6e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain SNF2_N PF00176.18 EPY50176.1 - 5.5e-72 242.0 1.0 1e-71 241.2 0.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY50176.1 - 1.4e-14 53.6 1.6 2.4e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY50176.1 - 6.6e-10 39.1 0.0 6.6e-10 39.1 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.8 EPY50176.1 - 9.6e-06 25.2 0.5 9.6e-06 25.2 0.3 3.8 2 1 2 4 4 4 1 HSA DEAD PF00270.24 EPY50176.1 - 1.4e-05 24.6 0.0 4.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4131 PF13567.1 EPY50177.1 - 7.1 5.9 12.6 24 4.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PDZ PF00595.19 EPY50179.1 - 9.7e-05 22.4 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EPY50179.1 - 0.00056 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EPY50179.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF3276 PF11680.3 EPY50179.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Prefoldin_2 PF01920.15 EPY50179.1 - 7.6 6.3 9.7 6.3 6.6 3.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit Zn_clus PF00172.13 EPY50180.1 - 1.2e-07 31.4 9.9 2.5e-07 30.5 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_1 PF00018.23 EPY50183.1 - 1.4e-34 117.1 3.9 7.5e-17 60.4 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EPY50183.1 - 5.1e-33 112.4 6.1 2.6e-16 58.9 0.2 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EPY50183.1 - 1.6e-28 97.9 0.4 3.4e-13 48.8 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EPY50183.1 - 5.9e-10 39.1 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DPPIV_N PF00930.16 EPY50184.1 - 2.4e-57 194.1 0.2 3.1e-57 193.7 0.1 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EPY50184.1 - 1.2e-27 96.5 0.0 2.1e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPY50184.1 - 4.5e-07 29.7 0.0 8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY50184.1 - 0.0043 16.9 0.0 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EPY50184.1 - 0.11 11.7 0.0 0.61 9.3 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family ATP-synt_ab PF00006.20 EPY50185.1 - 2.5e-70 236.3 0.0 3.4e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPY50185.1 - 4e-25 88.4 0.0 8.9e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPY50185.1 - 4.2e-17 62.1 0.9 1.1e-16 60.8 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPY50185.1 - 0.055 13.3 0.2 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 HAS barrel domain Rad17 PF03215.10 EPY50186.1 - 2.9e-108 362.8 1.2 3.7e-108 362.4 0.9 1.0 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EPY50186.1 - 1.2e-07 31.9 0.1 8.2e-07 29.2 0.0 2.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY50186.1 - 4.8e-06 26.7 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY50186.1 - 0.00011 22.2 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EPY50186.1 - 0.00021 21.1 0.0 0.00069 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPY50186.1 - 0.00023 21.4 0.0 0.00077 19.7 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 EPY50186.1 - 0.00035 20.8 0.0 0.0041 17.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EPY50186.1 - 0.001 18.7 0.0 0.0025 17.5 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 EPY50186.1 - 0.0011 18.6 0.0 0.0031 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPY50186.1 - 0.0013 18.8 0.0 0.0044 17.1 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EPY50186.1 - 0.0029 18.4 0.0 0.0096 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPY50186.1 - 0.0032 17.4 0.0 0.0065 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPY50186.1 - 0.0068 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RuvB_N PF05496.7 EPY50186.1 - 0.0081 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Guanylate_kin PF00625.16 EPY50186.1 - 0.0094 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EPY50186.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPY50186.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EPY50186.1 - 0.027 14.2 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EPY50186.1 - 0.047 13.1 0.2 5.7 6.3 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 EPY50186.1 - 0.07 11.9 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EPY50186.1 - 0.07 12.6 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EPY50186.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SWIRM PF04433.12 EPY50187.1 - 7e-13 48.5 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain VTC PF09359.5 EPY50188.1 - 2.1e-79 266.5 0.4 2.1e-79 266.5 0.3 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EPY50188.1 - 5.5e-20 72.2 14.8 1.8e-09 37.7 1.5 3.9 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EPY50188.1 - 4.8e-10 39.5 1.6 4.8e-10 39.5 1.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ABC2_membrane_5 PF13346.1 EPY50188.1 - 0.057 12.7 0.6 0.086 12.1 0.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein NMN_transporter PF04973.7 EPY50188.1 - 0.08 12.4 1.0 0.13 11.6 0.7 1.2 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter NUDIX PF00293.23 EPY50189.1 - 9.7e-18 64.1 0.0 1.5e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DBC1 PF14443.1 EPY50189.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 DBC1 Glyco_hydro_71 PF03659.9 EPY50190.1 - 1.1e-114 382.8 5.9 1.3e-114 382.6 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF1506 PF07405.6 EPY50191.1 - 0.059 13.3 0.1 0.083 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) Spore_IV_A PF09547.5 EPY50191.1 - 0.097 11.3 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) MFS_1 PF07690.11 EPY50192.1 - 1e-16 60.6 20.0 2.8e-14 52.6 3.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily FhuF_C PF11575.3 EPY50192.1 - 0.31 10.7 3.7 0.22 11.1 0.4 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain NAD_binding_2 PF03446.10 EPY50193.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase EnY2 PF10163.4 EPY50193.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 MSC PF09402.5 EPY50194.1 - 3.4e-33 114.7 13.7 1.9e-31 109.0 9.5 2.2 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EPY50194.1 - 9.7e-15 53.8 0.1 3.3e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 HeH/LEM domain Pkinase PF00069.20 EPY50196.1 - 1.6e-62 210.9 0.1 4.1e-62 209.6 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50196.1 - 5.8e-28 97.6 0.0 1.1e-27 96.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPY50196.1 - 4.2e-11 42.8 0.1 1.3e-10 41.1 0.1 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EPY50196.1 - 8.1e-05 21.7 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPY50196.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Dad3 PF08656.5 EPY50197.1 - 9.5e-23 79.7 1.3 1.1e-22 79.5 0.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Spore_YpjB PF09577.5 EPY50197.1 - 0.014 14.9 0.2 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) SMC_N PF02463.14 EPY50198.1 - 6.7e-26 90.8 0.3 2.6e-25 88.9 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPY50198.1 - 1.6e-19 71.0 3.1 1.6e-19 71.0 2.1 5.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EPY50198.1 - 1.7e-06 28.2 11.3 1.3e-05 25.3 1.5 3.8 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPY50198.1 - 0.00052 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EPY50198.1 - 0.011 16.0 0.0 0.011 16.0 0.0 4.4 3 2 0 3 3 3 0 ABC transporter MobB PF03205.9 EPY50198.1 - 0.039 13.6 0.8 2.6 7.7 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Reo_sigmaC PF04582.7 EPY50198.1 - 0.31 10.1 13.6 0.023 13.8 0.6 3.8 2 2 2 4 4 4 0 Reovirus sigma C capsid protein FtsK_SpoIIIE PF01580.13 EPY50198.1 - 1.9 7.8 5.9 8.9 5.7 0.0 3.4 4 1 0 4 4 4 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EPY50198.1 - 2.1 9.1 7.7 0.52 11.1 1.0 3.5 2 2 0 2 2 2 0 AAA domain DUF1770 PF08589.5 EPY50199.1 - 1.6e-13 51.0 5.5 5.2e-13 49.4 3.8 1.9 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) TLP-20 PF06088.6 EPY50199.1 - 0.16 11.6 2.0 0.27 10.8 1.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nop14 PF04147.7 EPY50199.1 - 0.38 8.6 11.2 0.41 8.5 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family alpha-hel2 PF14456.1 EPY50199.1 - 3.2 6.4 6.6 5.3 5.7 4.6 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 CDC45 PF02724.9 EPY50199.1 - 3.4 5.6 7.6 4 5.3 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EPY50199.1 - 4.4 4.9 17.4 5.6 4.6 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2890 PF11081.3 EPY50199.1 - 5.9 6.8 12.6 9.3 6.2 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 EPY50199.1 - 6 6.0 6.0 7.5 5.7 4.1 1.1 1 0 0 1 1 1 0 NOA36 protein Aminotran_3 PF00202.16 EPY50200.1 - 6.3e-85 284.9 0.0 7.5e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPY50200.1 - 0.069 12.0 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II RAI1 PF08652.6 EPY50201.1 - 8.4e-24 83.1 0.0 4.7e-23 80.7 0.0 2.1 1 1 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Ctf8 PF09696.5 EPY50202.1 - 5.1e-17 61.7 0.9 1.7e-16 60.0 0.6 1.8 1 1 0 1 1 1 1 Ctf8 Ribosomal_S4 PF00163.14 EPY50203.1 - 1.1e-15 57.7 1.3 2.2e-15 56.7 0.6 1.7 3 0 0 3 3 3 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPY50203.1 - 1.4e-12 46.8 0.0 3.5e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 S4 domain DUF913 PF06025.7 EPY50204.1 - 1.3e-98 330.2 5.1 3.1e-96 322.4 1.9 3.3 2 1 1 3 3 3 2 Domain of Unknown Function (DUF913) HECT PF00632.20 EPY50204.1 - 3.6e-95 318.7 0.0 9.5e-95 317.3 0.0 1.8 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EPY50204.1 - 9.6e-58 196.0 9.5 9.6e-58 196.0 6.6 3.4 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EPY50204.1 - 2.4e-14 53.1 1.8 2.4e-14 53.1 1.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) PAP_assoc PF03828.14 EPY50205.1 - 8.8e-19 67.2 0.1 2.4e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPY50205.1 - 2.4e-06 27.8 0.0 5.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EPY50205.1 - 0.00026 19.9 0.0 0.36 9.6 0.0 2.5 3 0 0 3 3 3 2 Poly(A) polymerase central domain Peroxin-22 PF12827.2 EPY50206.1 - 0.0095 15.6 0.0 0.16 11.6 0.0 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family Y_phosphatase PF00102.22 EPY50207.1 - 1.2e-62 211.3 0.1 1.7e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EPY50207.1 - 1.4e-08 35.0 0.0 1e-07 32.3 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 EPY50207.1 - 0.00028 20.9 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EPY50207.1 - 0.0014 18.2 0.0 0.0062 16.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EPY50207.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Ribos_L4_asso_C PF14374.1 EPY50207.1 - 0.016 15.0 0.1 0.044 13.6 0.1 1.7 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain DUF543 PF04418.7 EPY50208.1 - 5.3e-25 87.1 0.2 5.8e-25 87.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Yippee-Mis18 PF03226.9 EPY50209.1 - 2.6e-15 56.2 0.9 3.1e-15 56.0 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Sec7 PF01369.15 EPY50210.1 - 1.3e-37 129.3 0.8 2.5e-37 128.3 0.6 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EPY50210.1 - 8.6e-12 45.1 0.2 7.9e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EPY50210.1 - 3.1e-06 27.3 0.1 1.4e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Pinin_SDK_memA PF04696.8 EPY50211.1 - 6.3e-19 67.8 22.9 1e-18 67.2 15.9 1.3 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region SOBP PF15279.1 EPY50211.1 - 2.3 8.5 6.3 2.7 8.3 4.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CPSF73-100_C PF11718.3 EPY50211.1 - 3.7 6.8 8.7 4.8 6.4 6.1 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term IncA PF04156.9 EPY50211.1 - 4.7 6.7 14.6 5.7 6.4 10.1 1.3 1 0 0 1 1 1 0 IncA protein E1_dh PF00676.15 EPY50212.1 - 6.6e-118 392.7 0.0 7.9e-118 392.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EPY50212.1 - 0.0039 16.1 0.0 0.0064 15.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase ADH_zinc_N PF00107.21 EPY50213.1 - 2e-14 53.2 0.0 3.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPY50213.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain His_Phos_1 PF00300.17 EPY50214.1 - 6e-43 146.6 0.0 7.1e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldo_ket_red PF00248.16 EPY50215.1 - 9.9e-55 185.3 0.0 1.2e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ALMT PF11744.3 EPY50216.1 - 1.4e-21 76.6 22.2 1.5e-16 60.1 7.4 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.1 EPY50216.1 - 1.8e-16 60.1 28.9 7.3e-14 51.7 9.3 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 EPY50216.1 - 3.1e-15 55.9 9.6 3.7e-09 35.9 0.2 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EPY50216.1 - 1.5e-11 44.3 0.8 3.3e-11 43.2 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EPY50216.1 - 5.2e-09 35.1 11.1 5.2e-09 35.1 7.7 1.9 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF939 PF06081.6 EPY50216.1 - 5.9e-06 26.1 4.8 5.9e-06 26.1 3.3 2.6 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF939) RabGAP-TBC PF00566.13 EPY50217.1 - 1.6e-39 135.5 0.6 1.6e-39 135.5 0.4 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Y_phosphatase PF00102.22 EPY50218.1 - 5.6e-64 215.6 0.1 8.4e-64 215.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EPY50218.1 - 1.9e-07 31.4 0.0 1.9e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain PTPlike_phytase PF14566.1 EPY50218.1 - 1.8e-05 24.8 0.0 4.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EPY50218.1 - 0.001 18.6 0.0 0.0031 17.0 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EPY50218.1 - 0.0019 18.4 0.0 0.0089 16.2 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family WTF PF03303.8 EPY50219.1 - 3.6e-10 39.6 8.4 7.6e-09 35.3 5.8 2.0 1 1 0 1 1 1 1 WTF protein DUF204 PF02659.10 EPY50220.1 - 0.11 12.6 0.6 0.11 12.6 0.4 2.1 2 1 1 3 3 3 0 Domain of unknown function DUF DUF383 PF04063.9 EPY50221.1 - 1.7e-69 233.2 2.9 5.6e-69 231.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EPY50221.1 - 6.3e-23 80.1 2.1 2.3e-22 78.3 1.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF384) GlgS PF08971.6 EPY50221.1 - 0.066 13.1 0.1 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein HEAT_2 PF13646.1 EPY50221.1 - 0.13 12.5 0.6 4 7.7 0.0 3.0 2 1 0 2 2 2 0 HEAT repeats tRNA-synt_1 PF00133.17 EPY50222.1 - 1e-43 149.2 0.0 1.1e-31 109.5 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPY50222.1 - 2.1e-19 69.4 0.0 1e-10 40.8 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPY50222.1 - 1e-13 51.3 0.2 3.2e-13 49.7 0.1 1.9 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EPY50222.1 - 1.3e-09 37.6 0.0 2.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain bZIP_1 PF00170.16 EPY50222.1 - 0.091 12.7 1.0 0.24 11.3 0.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor Pyr_redox_2 PF07992.9 EPY50223.1 - 9.6e-35 120.2 1.2 5.6e-33 114.5 0.8 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPY50223.1 - 2.5e-17 63.0 0.4 3e-11 43.5 0.1 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EPY50223.1 - 6.9e-12 44.7 0.0 1.4e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EPY50223.1 - 1.1e-09 38.7 0.0 1.6e-05 25.1 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPY50223.1 - 4.4e-06 25.8 0.0 0.075 11.9 0.0 3.2 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EPY50223.1 - 7.6e-06 25.0 0.0 0.98 8.2 0.0 4.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase Reductase_C PF14759.1 EPY50223.1 - 1.8e-05 24.9 0.0 5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.9 EPY50223.1 - 5.9e-05 21.7 0.0 0.094 11.1 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.1 EPY50223.1 - 0.0002 21.1 0.0 3.1 7.5 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding Rieske_2 PF13806.1 EPY50223.1 - 0.0006 19.4 0.0 0.0052 16.4 0.0 2.5 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_8 PF13450.1 EPY50223.1 - 0.0012 18.7 0.1 0.0079 16.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 EPY50223.1 - 0.0023 17.6 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EPY50223.1 - 0.0044 15.9 0.2 0.14 10.9 0.0 2.7 2 1 1 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 EPY50223.1 - 0.035 13.1 0.5 4.1 6.3 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.13 EPY50223.1 - 0.087 12.8 0.5 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.9 EPY50223.1 - 0.13 10.9 0.0 0.29 9.7 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.15 EPY50223.1 - 0.13 12.3 0.1 0.79 9.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase EF1G PF00647.14 EPY50224.1 - 1.5e-42 143.6 0.0 3.4e-42 142.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EPY50224.1 - 1.1e-11 44.6 0.0 3.9e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPY50224.1 - 1.5e-09 37.6 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPY50224.1 - 1.9e-06 27.6 0.0 4.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY50224.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPY50224.1 - 0.00014 21.9 0.0 0.0003 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_S9 PF00380.14 EPY50225.1 - 8.6e-37 126.0 0.3 1.3e-36 125.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DKCLD PF08068.7 EPY50226.1 - 9.4e-30 102.3 0.3 5.3e-29 99.9 0.0 2.4 3 0 0 3 3 3 1 DKCLD (NUC011) domain PUA PF01472.15 EPY50226.1 - 2.6e-22 78.2 1.6 4.9e-22 77.4 1.1 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.13 EPY50226.1 - 3.5e-20 72.6 6.0 5.1e-19 68.9 0.0 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) RNase_H2-Ydr279 PF09468.5 EPY50226.1 - 0.12 11.5 22.2 0.19 10.9 15.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RNA_polI_A34 PF08208.6 EPY50226.1 - 0.32 10.6 45.9 0.49 10.0 31.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1510 PF07423.6 EPY50226.1 - 1.9 7.7 30.2 2.7 7.3 20.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 EPY50226.1 - 4.4 7.1 25.7 6.1 6.6 17.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF-hand_1 PF00036.27 EPY50227.1 - 2.3e-16 57.7 0.1 4e-05 22.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EPY50227.1 - 2.2e-13 50.1 0.2 3.2e-09 36.7 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPY50227.1 - 4.7e-13 47.8 0.0 0.00037 20.1 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.1 EPY50227.1 - 6.3e-11 42.0 0.0 9.1e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EPY50227.1 - 5.3e-10 38.7 2.6 0.00072 19.1 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EPY50227.1 - 0.00011 21.3 0.3 0.15 11.4 0.0 2.9 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.5 EPY50227.1 - 0.029 14.3 1.2 0.066 13.1 0.8 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand RloB PF13707.1 EPY50227.1 - 0.051 13.2 0.8 0.076 12.6 0.6 1.6 1 1 0 1 1 1 0 RloB-like protein DUF2040 PF09745.4 EPY50228.1 - 1.8e-29 102.1 20.3 1.8e-29 102.1 14.1 3.9 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF4574 PF15141.1 EPY50228.1 - 2.2 8.0 12.7 5.7 6.7 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4574) Med22 PF06179.7 EPY50229.1 - 1.3e-19 70.1 0.7 1.7e-19 69.8 0.5 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Prp19 PF08606.6 EPY50230.1 - 1.5e-29 101.5 1.9 1.5e-29 101.5 1.3 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like BBS2_Mid PF14783.1 EPY50230.1 - 0.00014 21.5 0.0 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region U-box PF04564.10 EPY50230.1 - 0.00033 20.5 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain WD40 PF00400.27 EPY50230.1 - 0.00041 20.1 3.2 0.017 14.9 0.0 4.4 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF3312 PF11768.3 EPY50230.1 - 0.012 13.8 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EPY50230.1 - 0.015 14.8 0.0 0.063 12.8 0.0 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Nop25 PF09805.4 EPY50231.1 - 6.6e-27 94.2 25.2 6.6e-27 94.2 17.4 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF3333 PF11812.3 EPY50231.1 - 0.016 15.2 1.7 0.03 14.3 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Herpes_UL25 PF01499.11 EPY50231.1 - 7.3 4.7 8.5 11 4.1 5.9 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Atg14 PF10186.4 EPY50231.1 - 9.4 5.0 11.2 8.8 5.1 4.5 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 VAR1 PF05316.7 EPY50232.1 - 0.022 13.3 0.1 0.04 12.5 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) RhoGAP PF00620.22 EPY50233.1 - 1.7e-43 147.8 0.7 4e-43 146.6 0.5 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EPY50233.1 - 2e-16 59.8 21.8 1.2e-10 41.2 2.5 4.3 4 1 0 4 4 4 2 LIM domain C1_1 PF00130.17 EPY50233.1 - 4.9e-05 22.9 5.7 4.9e-05 22.9 3.9 4.4 3 2 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LAT PF15234.1 EPY50234.1 - 0.033 13.6 0.8 0.033 13.6 0.5 1.4 2 0 0 2 2 2 0 Linker for activation of T-cells G6PD_bact PF10786.4 EPY50234.1 - 0.036 13.4 0.2 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF4526 PF15029.1 EPY50234.1 - 0.23 10.9 2.3 0.1 12.1 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) UreF PF01730.11 EPY50235.1 - 5e-14 52.6 0.0 6.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 UreF Peroxin-3 PF04882.7 EPY50236.1 - 2.5e-14 52.8 7.9 1.9e-11 43.3 5.5 3.2 1 1 0 1 1 1 1 Peroxin-3 tRNA-synt_2b PF00587.20 EPY50237.1 - 7.5e-36 123.2 0.1 1.3e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPY50237.1 - 1.2e-26 92.8 4.4 1.2e-26 92.8 3.0 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 EPY50237.1 - 0.059 13.0 4.7 0.026 14.2 1.6 1.6 2 0 0 2 2 2 0 Mnd1 family GED PF02212.13 EPY50237.1 - 0.34 10.8 3.1 0.75 9.7 2.1 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain DUF948 PF06103.6 EPY50237.1 - 0.97 9.3 3.0 4 7.3 2.1 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 EPY50238.1 - 1.8e-63 214.1 0.1 4.1e-63 212.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50238.1 - 4.2e-28 98.1 0.0 6.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50238.1 - 0.0082 15.1 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FUN14 PF04930.10 EPY50239.1 - 4.4e-19 68.6 0.2 5.6e-19 68.2 0.2 1.1 1 0 0 1 1 1 1 FUN14 family WD40 PF00400.27 EPY50240.1 - 8.5e-33 111.0 7.9 5.5e-08 32.4 0.1 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPY50240.1 - 7e-20 70.7 0.0 2.1e-19 69.1 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex E1-E2_ATPase PF00122.15 EPY50241.1 - 3.7e-28 98.1 0.0 7.6e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EPY50241.1 - 2e-15 57.4 0.0 3.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EPY50241.1 - 5.8e-14 51.9 0.0 5.8e-14 51.9 0.0 3.4 3 0 0 3 3 3 1 P5-type ATPase cation transporter Hydrolase PF00702.21 EPY50241.1 - 1.9e-10 41.5 0.0 3.8e-09 37.2 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY50241.1 - 2.1e-09 37.1 0.0 5.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPY50241.1 - 6.4e-07 28.7 0.2 1.4e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPY50241.1 - 0.014 15.0 0.1 0.039 13.5 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Radical_SAM PF04055.16 EPY50242.1 - 2.2e-19 70.2 0.1 6.3e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EPY50242.1 - 3.2e-13 49.5 0.0 1e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPY50242.1 - 0.038 14.1 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPY50242.1 - 0.087 12.9 0.2 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNF2_N PF00176.18 EPY50243.1 - 1.9e-81 273.1 1.1 4.9e-81 271.7 0.8 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EPY50243.1 - 6.5e-21 74.0 0.4 6.5e-21 74.0 0.3 2.3 2 0 0 2 2 2 1 Bromodomain HSA PF07529.8 EPY50243.1 - 3.4e-17 62.0 14.0 3.4e-17 62.0 9.7 3.0 2 0 0 2 2 2 1 HSA Helicase_C PF00271.26 EPY50243.1 - 5.9e-16 58.0 0.3 3.2e-15 55.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EPY50243.1 - 1.1e-12 47.9 7.2 1.1e-12 47.9 5.0 3.5 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex DUF3144 PF11342.3 EPY50244.1 - 0.052 13.6 0.1 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) UQ_con PF00179.21 EPY50245.1 - 1.6e-43 147.4 0.1 1.8e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPY50245.1 - 0.00092 18.9 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B TFIIIC_sub6 PF10419.4 EPY50246.1 - 4e-11 42.1 0.0 5.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit DNA_binding_1 PF01035.15 EPY50247.1 - 1.2e-25 89.0 0.0 1.4e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ribosomal_L7Ae PF01248.21 EPY50248.1 - 7.1e-24 83.1 0.0 9.1e-24 82.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family APP_Cu_bd PF12924.2 EPY50248.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD Pkinase PF00069.20 EPY50249.1 - 1.7e-60 204.4 0.0 2.9e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50249.1 - 1.2e-28 99.9 0.0 1.9e-27 95.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50249.1 - 0.00028 19.9 0.0 1.2 8.0 0.0 3.2 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EPY50249.1 - 0.037 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.24 EPY50251.1 - 1.8e-44 151.1 3.3 2.5e-44 150.7 0.6 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY50251.1 - 8.6e-27 92.8 0.5 4.6e-26 90.4 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY50251.1 - 0.00084 19.2 0.1 0.0025 17.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EPY50251.1 - 0.0014 18.2 0.4 0.0038 16.8 0.1 1.8 2 1 0 2 2 2 1 AAA domain Fanconi_A PF03511.9 EPY50251.1 - 0.0028 17.4 0.3 0.0053 16.5 0.2 1.5 1 0 0 1 1 1 1 Fanconi anaemia group A protein DUF1253 PF06862.7 EPY50251.1 - 0.0091 14.4 0.0 2.7 6.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EPY50251.1 - 0.033 13.9 1.5 0.069 12.9 0.1 2.2 2 1 0 3 3 3 0 Part of AAA domain UvrD-helicase PF00580.16 EPY50251.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 EPY50251.1 - 0.07 12.6 0.2 0.16 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 EPY50251.1 - 0.074 12.1 0.0 0.24 10.4 0.0 1.8 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EPY50251.1 - 0.082 12.6 0.3 0.33 10.7 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.9 EPY50251.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase CNH PF00780.17 EPY50252.1 - 2e-73 247.1 0.5 3.3e-73 246.4 0.1 1.6 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.15 EPY50252.1 - 4.1e-37 127.7 0.1 8.1e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EPY50252.1 - 5e-30 104.1 0.1 1.3e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.16 EPY50252.1 - 1.5e-13 50.2 0.0 3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Gly_transf_sug PF04488.10 EPY50253.1 - 6.5e-15 55.3 0.1 1.6e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPY50253.1 - 0.021 13.3 3.0 0.023 13.2 0.0 2.3 2 1 1 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain Reo_sigmaC PF04582.7 EPY50254.1 - 0.0049 16.0 7.6 0.0049 16.0 5.2 6.4 4 1 0 6 6 6 4 Reovirus sigma C capsid protein DUF58 PF01882.13 EPY50254.1 - 0.064 13.4 0.2 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF58 zf-C3H1 PF10650.4 EPY50255.1 - 1.9e-09 36.7 1.6 2.9e-09 36.2 1.1 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain WD40 PF00400.27 EPY50256.1 - 4.7e-23 80.1 7.4 4.9e-06 26.2 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Peptidase_S8 PF00082.17 EPY50257.1 - 8.8e-50 169.4 7.6 1.3e-49 168.9 5.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPY50257.1 - 1.7e-15 57.3 0.1 3.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 PQ-loop PF04193.9 EPY50258.1 - 9.5e-29 98.7 10.4 2.6e-17 62.0 0.7 2.5 2 0 0 2 2 2 2 PQ loop repeat Sod_Fe_C PF02777.13 EPY50259.1 - 5.3e-13 48.7 1.1 1.4e-06 28.0 0.2 2.4 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPY50259.1 - 0.00061 20.0 0.1 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Nepo_coat_N PF03689.10 EPY50259.1 - 0.029 14.1 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain Alpha-amylase PF00128.19 EPY50260.1 - 1.2e-63 215.3 0.0 2e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPY50260.1 - 4.7e-12 45.8 0.0 9.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF1493 PF07377.7 EPY50260.1 - 0.041 13.9 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Abhydrolase_1 PF00561.15 EPY50261.1 - 1e-20 74.3 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EPY50261.1 - 4e-20 70.9 0.1 7.3e-20 70.0 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EPY50261.1 - 5e-08 33.1 0.0 1.1e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY50261.1 - 4.5e-06 26.4 0.0 4.1e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPY50261.1 - 0.00096 18.6 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) DLH PF01738.13 EPY50261.1 - 0.0085 15.3 0.0 0.031 13.5 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EPY50261.1 - 0.089 12.2 0.2 8.2 5.7 0.1 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase IMS PF00817.15 EPY50262.1 - 1.5e-40 138.4 0.0 3.1e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family Acetyltransf_13 PF13880.1 EPY50262.1 - 5.3e-23 80.5 0.0 1.1e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EPY50262.1 - 6.1e-12 44.8 0.2 6.1e-12 44.8 0.2 3.3 3 1 0 3 3 3 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EPY50262.1 - 0.036 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY50262.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Mss51 PF13824.1 EPY50262.1 - 0.07 12.9 0.1 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 IMS_HHH PF11798.3 EPY50262.1 - 0.072 13.1 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 IMS family HHH motif MBOAT PF03062.14 EPY50263.1 - 1.4e-60 205.1 5.1 1.4e-60 205.1 3.5 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Eaf7 PF07904.8 EPY50264.1 - 1.3e-17 63.5 0.1 1.3e-17 63.5 0.1 2.0 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 AA_permease PF00324.16 EPY50265.1 - 2.4e-102 342.7 41.3 3.1e-102 342.3 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY50265.1 - 1.8e-34 119.0 43.0 2.3e-34 118.6 29.8 1.1 1 0 0 1 1 1 1 Amino acid permease Stb3 PF10330.4 EPY50267.1 - 1.5e-23 82.2 0.0 2.9e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein ERG4_ERG24 PF01222.12 EPY50268.1 - 2.3e-142 474.5 16.6 2.8e-142 474.2 11.5 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EPY50268.1 - 0.0009 18.6 2.3 0.0015 17.8 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EPY50268.1 - 0.0036 17.3 0.5 0.057 13.5 0.0 2.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Fungal_trans PF04082.13 EPY50269.1 - 2.6e-32 111.7 2.5 4.4e-32 110.9 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY50269.1 - 6.8e-13 48.2 11.7 1.2e-12 47.5 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fork_head PF00250.13 EPY50270.1 - 2.8e-38 129.8 1.5 5.6e-38 128.8 1.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPY50270.1 - 8.3e-08 32.2 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Ribosomal_S3_C PF00189.15 EPY50271.1 - 1.9e-15 56.8 0.0 3.6e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EPY50271.1 - 3e-14 52.3 0.0 6e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 KH domain FrhB_FdhB_N PF04422.8 EPY50271.1 - 0.032 14.0 0.2 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term FAD_binding_9 PF08021.6 EPY50271.1 - 0.095 12.6 0.1 0.27 11.1 0.0 1.7 1 1 1 2 2 2 0 Siderophore-interacting FAD-binding domain UN_NPL4 PF11543.3 EPY50271.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF4474 PF14751.1 EPY50272.1 - 0.011 14.9 0.2 0.016 14.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4474) OPA3 PF07047.7 EPY50272.1 - 0.047 13.4 0.1 11 5.8 0.2 2.0 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) Topoisom_bac PF01131.15 EPY50273.1 - 1.1e-89 301.0 0.0 1.3e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EPY50273.1 - 1.3e-20 73.2 0.0 2.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Toprim domain BAG PF02179.11 EPY50274.1 - 4.8e-15 55.4 4.0 4.8e-15 55.4 2.8 1.9 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 EPY50274.1 - 9.3e-06 24.9 0.1 2.5e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPY50274.1 - 5e-05 22.9 0.1 0.00014 21.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EPY50274.1 - 0.0035 17.2 0.0 0.014 15.3 0.0 2.0 1 1 1 2 2 2 1 GLUT4 regulating protein TUG V-ATPase_C PF03223.10 EPY50274.1 - 0.026 13.4 3.2 0.55 9.0 1.9 2.1 2 0 0 2 2 2 0 V-ATPase subunit C Sialidase PF02973.11 EPY50274.1 - 0.061 12.2 0.1 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Sialidase, N-terminal domain STAT_alpha PF01017.15 EPY50274.1 - 0.065 12.9 3.5 0.079 12.6 1.8 1.6 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF1828 PF08861.5 EPY50274.1 - 0.12 12.0 1.7 0.2 11.2 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF1828 SAS4 PF15460.1 EPY50274.1 - 0.17 11.7 5.3 10 6.0 3.7 2.4 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 RNase_PH PF01138.16 EPY50275.1 - 1.7e-15 57.4 0.1 2.6e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_S10 PF00450.17 EPY50276.1 - 7.4e-106 354.7 1.3 8.6e-106 354.5 0.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPY50276.1 - 0.057 13.3 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glycos_transf_3 PF00591.16 EPY50277.1 - 1.6e-79 266.9 0.0 2e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EPY50277.1 - 9.8e-07 28.2 0.0 2.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Band_7 PF01145.20 EPY50278.1 - 3.1e-28 98.8 1.1 4.2e-28 98.4 0.1 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EPY50278.1 - 0.011 15.3 0.2 0.049 13.1 0.0 2.0 2 1 0 2 2 2 0 SPFH domain-Band 7 family PhyH PF05721.8 EPY50278.1 - 0.079 12.9 0.1 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) PE PF00934.15 EPY50278.1 - 2.7 8.1 8.2 0.26 11.3 0.4 2.6 2 1 1 3 3 3 0 PE family EphA2_TM PF14575.1 EPY50279.1 - 0.038 14.3 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EPY50279.1 - 0.054 13.6 0.3 0.81 9.8 0.0 2.3 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4614 PF15391.1 EPY50279.1 - 0.7 9.6 7.3 0.95 9.2 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DNA_pol_viral_N PF00242.12 EPY50279.1 - 5.2 6.0 6.2 6.5 5.6 4.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Motile_Sperm PF00635.21 EPY50280.1 - 3e-24 84.7 0.1 6.7e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Ribosomal_L13 PF00572.13 EPY50281.1 - 2.2e-44 150.5 0.0 2.6e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 zf-RING_2 PF13639.1 EPY50282.1 - 1.9e-08 33.9 6.3 3.5e-08 33.1 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPY50282.1 - 2.3e-07 30.3 4.3 4.5e-07 29.4 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY50282.1 - 1.3e-06 28.2 4.2 2.4e-06 27.4 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY50282.1 - 3e-06 26.8 6.5 4.7e-06 26.1 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPY50282.1 - 0.00012 22.0 5.5 0.00034 20.6 3.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPY50282.1 - 0.00076 19.1 5.1 0.0014 18.3 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPY50282.1 - 0.17 11.7 3.2 0.34 10.7 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPY50282.1 - 0.2 11.7 4.0 0.58 10.2 2.8 1.8 1 1 0 1 1 1 0 RING-variant domain DUF999 PF06198.6 EPY50283.1 - 0.016 15.0 1.2 0.025 14.3 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF999) PfkB PF00294.19 EPY50284.1 - 1.8e-65 221.0 0.4 2e-65 220.8 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPY50284.1 - 4.6e-08 32.5 0.3 7e-08 31.9 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase SAC3_GANP PF03399.11 EPY50285.1 - 5.3e-26 91.4 0.5 7.3e-26 90.9 0.4 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPY50285.1 - 4.2e-22 78.4 0.6 9.8e-22 77.2 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EPY50285.1 - 0.0013 19.0 0.6 0.074 13.3 0.1 2.8 2 1 0 2 2 2 1 PCI domain KAT11 PF08214.6 EPY50286.1 - 6.4e-62 209.6 0.5 7.6e-62 209.3 0.3 1.0 1 0 0 1 1 1 1 Histone acetylation protein Innexin PF00876.13 EPY50286.1 - 0.049 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Innexin BRCT PF00533.21 EPY50287.1 - 9.7e-09 35.2 0.4 3.1e-08 33.6 0.3 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad9_Rad53_bind PF08605.5 EPY50287.1 - 4.3e-06 26.5 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Rho_RNA_bind PF07497.7 EPY50287.1 - 0.0086 15.6 0.0 3 7.5 0.0 2.6 2 0 0 2 2 2 2 Rho termination factor, RNA-binding domain Toxin_57 PF15535.1 EPY50287.1 - 0.68 10.0 3.3 0.34 11.0 0.4 1.9 2 0 0 2 2 2 0 Putative toxin 57 Proteasom_Rpn13 PF04683.8 EPY50288.1 - 9e-24 83.3 0.0 1.9e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF1400 PF07176.6 EPY50288.1 - 0.039 13.8 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Glyco_hydro_72 PF03198.9 EPY50289.1 - 4.2e-136 453.0 2.5 5.4e-136 452.6 1.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EPY50289.1 - 9.2e-06 25.0 0.6 0.0001 21.6 0.5 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPY50289.1 - 0.011 14.7 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain tRNA-synt_1c PF00749.16 EPY50290.1 - 2.1e-105 351.8 0.0 3.3e-105 351.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EPY50290.1 - 2.9e-49 166.7 1.0 4.8e-49 166.0 0.7 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EPY50290.1 - 6.4e-34 117.1 0.1 2.3e-32 112.0 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EPY50290.1 - 6.1e-18 65.2 5.7 1.3e-17 64.2 4.0 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 NA37 PF04245.8 EPY50290.1 - 0.032 13.5 0.1 0.068 12.5 0.1 1.5 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein DUF1002 PF06207.6 EPY50290.1 - 0.1 11.8 0.6 0.2 10.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Stk19 PF10494.4 EPY50291.1 - 5.3e-41 140.6 0.1 5.3e-41 140.6 0.1 1.4 2 0 0 2 2 2 1 Serine-threonine protein kinase 19 POTRA_2 PF08479.6 EPY50291.1 - 0.004 16.7 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 POTRA domain, ShlB-type Endonuc_BglI PF14562.1 EPY50291.1 - 0.037 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI AAA PF00004.24 EPY50293.1 - 7e-52 175.1 0.0 2.1e-40 137.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPY50293.1 - 2.9e-11 43.1 0.0 6.6e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EPY50293.1 - 1.5e-09 37.3 0.1 1.4e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EPY50293.1 - 3.1e-09 37.0 0.5 0.00041 20.4 0.1 4.2 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EPY50293.1 - 2.5e-08 34.0 0.0 1.4e-06 28.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EPY50293.1 - 4.6e-08 32.1 0.0 0.0034 16.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EPY50293.1 - 4.2e-07 29.9 0.0 0.029 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPY50293.1 - 9.2e-07 28.7 0.3 0.85 9.2 0.0 4.1 2 2 2 4 4 4 1 Archaeal ATPase AAA_17 PF13207.1 EPY50293.1 - 2.2e-06 28.4 0.0 0.0017 19.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPY50293.1 - 3.3e-06 27.2 0.0 0.0067 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 EPY50293.1 - 6.8e-06 25.2 0.2 0.021 13.8 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EPY50293.1 - 2.3e-05 24.7 0.0 0.0048 17.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPY50293.1 - 6.6e-05 22.5 2.7 0.02 14.6 0.0 2.9 3 0 0 3 3 2 1 Part of AAA domain AAA_5 PF07728.9 EPY50293.1 - 9.1e-05 22.1 0.2 0.001 18.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPY50293.1 - 0.00019 21.3 0.0 0.089 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPY50293.1 - 0.00024 20.3 0.3 0.0046 16.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EPY50293.1 - 0.00053 19.6 0.1 0.69 9.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EPY50293.1 - 0.001 18.4 0.4 0.046 13.1 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EPY50293.1 - 0.0012 17.9 0.1 0.76 8.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 EPY50293.1 - 0.0018 18.5 0.1 0.015 15.5 0.0 2.4 3 0 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.21 EPY50293.1 - 0.0024 17.3 0.1 0.48 9.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EPY50293.1 - 0.0038 16.6 3.7 0.75 9.1 0.0 3.7 2 2 2 4 4 4 1 AAA domain KaiC PF06745.8 EPY50293.1 - 0.005 15.9 0.5 0.024 13.7 0.1 2.2 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.17 EPY50293.1 - 0.0076 16.4 0.0 0.063 13.4 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 EPY50293.1 - 0.018 14.6 0.9 0.11 12.0 0.1 2.5 3 0 0 3 3 2 0 AAA domain Parvo_NS1 PF01057.12 EPY50293.1 - 0.026 13.3 0.0 0.38 9.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 T2SE PF00437.15 EPY50293.1 - 0.027 13.3 0.2 4.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 EPY50293.1 - 0.028 13.6 0.0 1.4 8.0 0.0 2.5 3 0 0 3 3 2 0 PhoH-like protein Myc_target_1 PF15179.1 EPY50293.1 - 0.043 13.3 0.4 0.078 12.5 0.3 1.3 1 0 0 1 1 1 0 Myc target protein 1 AAA_28 PF13521.1 EPY50293.1 - 0.043 13.7 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EPY50293.1 - 0.062 12.2 0.0 0.31 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EPY50293.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EPY50293.1 - 0.079 12.5 0.1 4.3 6.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.7 EPY50293.1 - 0.11 12.1 2.3 5.1 6.7 0.0 3.7 5 0 0 5 5 5 0 NACHT domain HATPase_c PF02518.21 EPY50294.1 - 2.6e-20 72.1 0.1 5.4e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPY50294.1 - 6.6e-19 67.9 0.1 2.5e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPY50294.1 - 2.3e-15 56.3 0.1 4.6e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EPY50294.1 - 5.2e-15 55.6 0.0 5.2e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 EPY50294.1 - 4.2e-14 52.4 0.0 1.8e-06 27.9 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 EPY50294.1 - 5.3e-14 51.9 0.0 1.4e-08 34.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EPY50294.1 - 3.5e-11 43.1 0.0 2.3e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EPY50294.1 - 3.5e-09 36.2 0.0 8.1e-05 22.3 0.0 2.8 2 0 0 2 2 2 2 PAS domain Kinesin PF00225.18 EPY50295.1 - 3.2e-111 371.2 2.3 5.9e-111 370.3 1.6 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF745 PF05335.8 EPY50295.1 - 2 7.9 6.6 0.17 11.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Mo25 PF08569.6 EPY50296.1 - 4e-123 410.7 14.0 4.5e-123 410.5 9.7 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 EPY50296.1 - 0.027 14.7 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats DUF4423 PF14394.1 EPY50296.1 - 0.03 13.8 0.0 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Glyco_transf_22 PF03901.12 EPY50297.1 - 5.1e-106 355.1 31.1 5.9e-106 354.9 21.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Histone PF00125.19 EPY50298.1 - 6.8e-32 109.4 0.1 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPY50298.1 - 6.3e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPY50298.1 - 0.0024 17.8 0.2 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPY50298.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EPY50299.1 - 7.2e-15 54.8 0.4 8.7e-15 54.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY50299.1 - 7.1e-06 25.9 0.1 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPY50299.1 - 5.8e-05 23.1 0.1 8.2e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EPY50299.1 - 8.5e-05 22.4 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 EPY50299.1 - 0.012 14.8 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EPY50299.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated DUF1819 PF08849.6 EPY50299.1 - 0.1 12.0 0.6 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) TFIID_20kDa PF03847.8 EPY50299.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A EPSP_synthase PF00275.15 EPY50300.1 - 4.3e-127 424.0 0.0 6.1e-127 423.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EPY50300.1 - 3.3e-95 317.9 0.0 5.2e-95 317.2 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EPY50300.1 - 6e-64 215.7 0.0 8.9e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EPY50300.1 - 6.6e-34 117.0 0.1 4.5e-33 114.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EPY50300.1 - 3.1e-24 84.8 0.0 9.2e-24 83.3 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EPY50300.1 - 4.2e-13 49.5 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EPY50300.1 - 9.7e-08 31.6 0.0 2.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EPY50300.1 - 2.3e-07 31.6 0.0 6.5e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY50300.1 - 0.00051 20.3 0.2 0.0048 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPY50300.1 - 0.0058 16.5 0.0 0.13 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPY50300.1 - 0.013 15.3 0.0 0.056 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EPY50300.1 - 0.022 14.9 0.0 0.091 12.9 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EPY50300.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.1 EPY50300.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family eRF1_2 PF03464.10 EPY50301.1 - 2.8e-45 153.8 0.1 5.5e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPY50301.1 - 5e-38 129.8 1.1 1e-37 128.8 0.7 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EPY50301.1 - 9.8e-26 89.8 0.2 2.2e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 1 VanY PF02557.12 EPY50301.1 - 0.12 12.2 0.2 4.8 7.0 0.1 2.7 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase UAA PF08449.6 EPY50302.1 - 1.5e-13 50.3 22.5 2.1e-13 49.8 15.6 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPY50302.1 - 6.5e-10 38.8 5.7 6.5e-10 38.8 4.0 2.7 1 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EPY50302.1 - 0.0013 18.7 26.9 0.0015 18.5 4.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 EPY50302.1 - 0.0025 16.5 5.3 0.0025 16.5 3.7 2.5 1 1 1 2 2 2 1 Phosphate transporter family 6PF2K PF01591.13 EPY50303.1 - 9.3e-53 178.5 0.7 1.5e-52 177.9 0.5 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EPY50303.1 - 9.4e-07 28.7 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPY50303.1 - 5.3e-06 25.8 0.1 1.3e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 His_Phos_1 PF00300.17 EPY50303.1 - 9.3e-06 25.8 0.0 3.2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF59 PF01883.14 EPY50304.1 - 3.6e-09 36.4 0.0 6.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Vps51 PF08700.6 EPY50305.1 - 2.2e-13 49.8 5.3 4.8e-13 48.7 2.3 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Kinesin PF00225.18 EPY50306.1 - 1.9e-71 240.5 0.1 2.8e-71 239.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Rtt102p PF09510.5 EPY50306.1 - 0.013 15.5 0.9 0.027 14.4 0.1 2.0 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein TPR_MLP1_2 PF07926.7 EPY50306.1 - 0.018 14.7 3.7 0.05 13.3 2.6 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PSD3 PF07626.6 EPY50306.1 - 0.028 14.4 1.3 7 6.7 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1587) DUF4460 PF14687.1 EPY50306.1 - 0.26 11.0 0.1 0.26 11.0 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4460) WD40 PF00400.27 EPY50307.1 - 1e-32 110.7 13.0 2e-06 27.4 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPY50307.1 - 2.3e-06 27.4 0.3 0.00052 19.7 0.1 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Rib_5-P_isom_A PF06026.9 EPY50308.1 - 2.4e-54 183.2 0.0 3.8e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ribosomal_S17 PF00366.15 EPY50309.1 - 6e-31 106.2 1.0 9.3e-31 105.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 GWT1 PF06423.7 EPY50310.1 - 1.8e-37 128.4 1.6 1.8e-37 128.4 1.1 3.2 3 1 0 3 3 3 1 GWT1 DUF1129 PF06570.6 EPY50310.1 - 0.0011 18.3 7.2 0.038 13.3 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1129) DUF1104 PF06518.6 EPY50311.1 - 0.23 11.5 7.2 0.081 13.0 1.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1104) ALMT PF11744.3 EPY50311.1 - 0.53 8.8 2.9 0.61 8.6 2.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter zf-C2H2 PF00096.21 EPY50312.1 - 2.7e-31 105.9 79.1 1.4e-05 25.1 0.2 10.4 10 1 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY50312.1 - 2.1e-21 74.6 72.4 0.00061 19.9 0.4 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPY50312.1 - 5.3e-17 61.1 72.5 0.00015 21.9 1.0 10.8 11 0 0 11 11 11 7 Zinc-finger double domain zf-met PF12874.2 EPY50312.1 - 4.3e-06 26.7 17.0 0.17 12.0 0.1 6.3 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPY50312.1 - 0.018 15.2 0.1 0.018 15.2 0.0 7.8 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding IBR PF01485.16 EPY50312.1 - 1 9.2 33.8 0.23 11.3 1.9 6.3 2 1 2 4 4 4 0 IBR domain zinc_ribbon_2 PF13240.1 EPY50312.1 - 1.1 8.8 9.3 0.85 9.1 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF1610 PF07754.6 EPY50312.1 - 5 7.3 14.5 0.26 11.4 0.4 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) HSCB_C PF07743.8 EPY50313.1 - 1.5e-16 60.5 0.9 3.2e-16 59.5 0.6 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EPY50313.1 - 3.7e-09 36.2 0.2 6.9e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain ATP_bind_1 PF03029.12 EPY50314.1 - 2.2e-78 263.0 0.0 2.7e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EPY50314.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain CbiA PF01656.18 EPY50314.1 - 0.0079 15.6 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EPY50314.1 - 0.0092 16.2 1.6 1.4 9.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EPY50314.1 - 0.0094 16.7 2.6 0.017 15.9 0.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EPY50314.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPY50314.1 - 0.014 14.1 0.0 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein MipZ PF09140.6 EPY50314.1 - 0.018 14.1 0.0 0.23 10.5 0.0 2.0 1 1 1 2 2 2 0 ATPase MipZ MMR_HSR1 PF01926.18 EPY50314.1 - 0.019 14.8 0.2 0.19 11.7 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EPY50314.1 - 0.038 14.1 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.5 EPY50314.1 - 0.059 12.5 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 EPY50314.1 - 0.062 13.0 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EPY50314.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EPY50314.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Adaptin_N PF01602.15 EPY50315.1 - 6.7e-95 318.3 14.7 8e-95 318.1 10.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EPY50315.1 - 4.1e-07 30.0 6.8 0.0084 15.9 0.1 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPY50315.1 - 9.7e-06 25.7 0.3 0.0098 16.1 0.0 3.3 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EPY50315.1 - 9.8e-05 22.1 6.2 2.8 8.2 0.1 4.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EPY50315.1 - 0.0034 17.8 0.6 9.1 6.9 0.0 3.9 3 0 0 3 3 3 1 HEAT-like repeat SNF2_N PF00176.18 EPY50316.1 - 6.1e-56 189.4 0.1 6.1e-56 189.4 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EPY50316.1 - 6.9e-09 35.3 10.6 1.9e-08 33.9 7.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY50316.1 - 1.8e-07 30.7 8.7 1.8e-07 30.7 6.0 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY50316.1 - 2.7e-07 30.1 10.9 8.7e-07 28.5 7.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY50316.1 - 3.9e-07 29.9 12.2 3.9e-07 29.9 8.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY50316.1 - 1.9e-05 24.3 10.3 5.6e-05 22.7 7.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 EPY50316.1 - 0.00011 22.0 0.0 0.00029 20.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.1 EPY50316.1 - 0.00088 18.7 4.5 0.002 17.6 3.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.6 EPY50316.1 - 0.0059 16.3 2.1 0.022 14.5 1.5 2.0 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EPY50316.1 - 0.019 14.8 9.7 0.047 13.5 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GAD PF02938.9 EPY50316.1 - 0.047 13.8 0.0 2.1 8.5 0.0 2.9 2 0 0 2 2 2 0 GAD domain zf-RING_UBOX PF13445.1 EPY50316.1 - 0.1 12.3 6.2 0.72 9.6 4.3 2.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EPY50316.1 - 1 9.4 17.4 0.062 13.4 7.7 2.2 2 1 0 2 2 1 0 RING-H2 zinc finger SNF2_N PF00176.18 EPY50317.1 - 6.3e-56 189.3 0.1 6.3e-56 189.3 0.1 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EPY50317.1 - 7.2e-09 35.3 10.6 2e-08 33.9 7.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY50317.1 - 1.8e-07 30.6 8.7 1.8e-07 30.6 6.0 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY50317.1 - 2.8e-07 30.0 10.9 8.9e-07 28.4 7.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY50317.1 - 4e-07 29.9 12.2 4e-07 29.9 8.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY50317.1 - 1.9e-05 24.2 10.3 5.7e-05 22.7 7.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EPY50317.1 - 0.0009 18.7 4.5 0.0021 17.5 3.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.26 EPY50317.1 - 0.017 14.9 0.0 0.057 13.2 0.0 2.0 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EPY50317.1 - 0.02 14.7 9.7 0.048 13.5 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GAD PF02938.9 EPY50317.1 - 0.048 13.8 0.0 2.1 8.5 0.0 2.9 2 0 0 2 2 2 0 GAD domain zf-RING_UBOX PF13445.1 EPY50317.1 - 0.11 12.2 6.4 0.78 9.5 4.4 2.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EPY50317.1 - 1.1 9.4 17.4 0.063 13.3 7.7 2.2 2 1 0 2 2 1 0 RING-H2 zinc finger CDC45 PF02724.9 EPY50318.1 - 8.6e-214 711.1 0.4 9.8e-214 710.9 0.3 1.0 1 0 0 1 1 1 1 CDC45-like protein DHH PF01368.15 EPY50318.1 - 0.0067 16.0 0.2 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 DHH family Cation_efflux PF01545.16 EPY50319.1 - 3e-58 197.1 5.0 3e-58 197.1 3.5 2.3 2 0 0 2 2 2 1 Cation efflux family Nol1_Nop2_Fmu PF01189.12 EPY50320.1 - 3.3e-33 115.2 0.0 3.2e-18 66.1 0.0 3.7 2 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 EPY50320.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EPY50320.1 - 0.018 15.5 0.0 0.05 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Spectrin PF00435.16 EPY50321.1 - 0.0049 17.1 3.7 0.0049 17.1 2.5 4.0 2 1 0 4 4 4 1 Spectrin repeat WXG100 PF06013.7 EPY50321.1 - 0.096 12.7 6.6 1.4 8.9 0.1 4.3 4 1 0 4 4 4 0 Proteins of 100 residues with WXG Reo_sigmaC PF04582.7 EPY50321.1 - 0.12 11.5 5.6 0.34 10.0 0.7 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EPY50321.1 - 0.16 11.8 13.8 0.42 10.4 6.2 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EPY50321.1 - 0.24 11.3 22.7 0.39 10.6 1.0 5.6 4 3 1 5 5 5 0 Flagella accessory protein C (FlaC) HBS1_N PF08938.5 EPY50321.1 - 1.1 9.4 7.5 0.61 10.2 1.1 3.6 3 1 0 3 3 3 0 HBS1 N-terminus TBPIP PF07106.8 EPY50321.1 - 1.3 8.5 41.9 3.7 7.0 0.7 5.0 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2215 PF10225.4 EPY50321.1 - 7.1 5.9 6.4 0.84 9.0 0.9 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2215) Telomere_reg-2 PF10193.4 EPY50322.1 - 4.3e-25 88.1 0.0 1.1e-24 86.8 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein DLIC PF05783.6 EPY50323.1 - 1.3e-13 50.5 0.9 2.8e-11 42.7 0.1 2.9 2 1 0 3 3 3 2 Dynein light intermediate chain (DLIC) APG12 PF04110.8 EPY50323.1 - 0.015 15.4 2.5 0.99 9.6 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 PI3Ka PF00613.15 EPY50324.1 - 6.9e-68 227.4 0.8 1.2e-67 226.6 0.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EPY50324.1 - 2.7e-47 161.2 0.0 2.4e-46 158.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EPY50324.1 - 3.6e-17 62.4 0.2 6.2e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 EPY50324.1 - 0.0039 16.2 0.0 0.0079 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) WD40 PF00400.27 EPY50325.1 - 7e-10 38.4 0.6 0.061 13.2 0.8 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat SIN1 PF05422.7 EPY50326.1 - 9.1e-135 450.1 6.7 1.2e-134 449.7 4.7 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) TFIIE_alpha PF02002.12 EPY50327.1 - 1.9e-14 53.0 1.0 3.5e-14 52.1 0.1 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EPY50327.1 - 0.0032 16.7 1.0 0.013 14.7 0.7 2.1 1 0 0 1 1 1 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EPY50327.1 - 0.06 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4428 PF14471.1 EPY50327.1 - 0.15 11.8 4.9 0.34 10.6 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) zf-C2H2_6 PF13912.1 EPY50327.1 - 0.47 10.4 0.1 0.47 10.4 0.1 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger PH PF00169.24 EPY50328.1 - 4.5e-09 36.4 0.5 1.5e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 PH domain Anillin PF08174.6 EPY50328.1 - 4.6e-05 23.4 0.1 0.00021 21.3 0.0 2.1 2 0 0 2 2 2 1 Cell division protein anillin TFIIS_C PF01096.13 EPY50329.1 - 3.2e-13 49.0 9.9 7.7e-13 47.8 0.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPY50329.1 - 7e-11 41.6 1.8 7e-11 41.6 1.2 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 EPY50329.1 - 0.001 18.7 2.5 0.092 12.4 0.1 2.1 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like DZR PF12773.2 EPY50329.1 - 0.0052 16.5 8.0 0.065 13.0 0.3 2.8 2 1 0 2 2 2 1 Double zinc ribbon DUF3716 PF12511.3 EPY50329.1 - 0.0054 16.3 4.5 0.65 9.6 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) Lar_restr_allev PF14354.1 EPY50329.1 - 0.021 15.1 6.8 0.026 14.7 0.7 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar C1_4 PF07975.7 EPY50329.1 - 0.23 11.4 7.8 0.43 10.6 0.3 3.1 2 1 1 3 3 3 0 TFIIH C1-like domain Ribosomal_L44 PF00935.14 EPY50329.1 - 0.34 10.9 3.5 3.1 7.8 0.2 2.7 3 0 0 3 3 3 0 Ribosomal protein L44 Zn_Tnp_IS1595 PF12760.2 EPY50329.1 - 0.5 10.2 11.1 0.17 11.6 2.1 2.6 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Cytochrome_C554 PF13435.1 EPY50329.1 - 0.76 9.8 5.2 0.26 11.3 2.0 1.4 2 0 0 2 2 1 0 Cytochrome c554 and c-prime HypA PF01155.14 EPY50329.1 - 0.91 9.2 5.9 5 6.8 2.4 2.5 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C4pol PF14260.1 EPY50329.1 - 1.2 9.2 5.2 8.4 6.4 1.6 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF2082 PF09855.4 EPY50329.1 - 1.5 8.7 9.2 2.5 8.0 0.2 3.6 2 2 1 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF3268 PF11672.3 EPY50329.1 - 2.1 8.5 5.0 4.2 7.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) ADK_lid PF05191.9 EPY50329.1 - 2.1 8.0 7.4 12 5.6 0.2 3.8 4 0 0 4 4 4 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 EPY50329.1 - 3.1 7.8 9.8 3.2 7.7 0.0 3.5 3 1 0 3 3 3 0 Zinc ribbon domain zf-3CxxC PF13695.1 EPY50329.1 - 4.3 7.6 6.7 1.9 8.7 0.6 2.3 1 1 1 2 2 2 0 Zinc-binding domain OrfB_Zn_ribbon PF07282.6 EPY50329.1 - 5.1 6.8 7.0 7.2 6.3 1.2 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 EPY50329.1 - 5.6 6.8 7.2 1.1 9.1 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbons DUF3795 PF12675.2 EPY50329.1 - 5.9 7.1 8.6 4.8e+02 1.0 6.0 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Nudix_N_2 PF14803.1 EPY50329.1 - 9.1 6.0 11.1 22 4.8 1.9 3.5 3 1 0 3 3 3 0 Nudix N-terminal P5CR_dimer PF14748.1 EPY50330.1 - 7.8e-35 119.1 2.4 5.3e-34 116.4 0.8 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EPY50330.1 - 5.3e-10 39.5 2.8 1e-09 38.6 0.3 2.7 4 1 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent RnfC_N PF13375.1 EPY50330.1 - 0.086 12.5 0.3 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Peptidase_C97 PF05903.9 EPY50331.1 - 4.6e-34 117.3 0.0 7.2e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EPY50331.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase Ecm29 PF13001.2 EPY50332.1 - 1.5e-54 185.3 6.2 7.3e-29 100.6 0.1 3.0 2 1 1 3 3 3 2 Proteasome stabiliser HEAT PF02985.17 EPY50332.1 - 5.5e-08 32.2 1.8 0.29 11.3 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EPY50332.1 - 8e-06 26.1 0.6 0.52 10.7 0.0 5.6 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EPY50332.1 - 6e-05 23.2 0.3 4.5 7.6 0.0 6.3 7 1 0 7 7 7 1 HEAT repeats Ilm1 PF10311.4 EPY50333.1 - 1.9e-28 99.0 9.4 3.2e-28 98.3 6.5 1.3 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 YwiC PF14256.1 EPY50333.1 - 0.3 11.1 7.2 0.86 9.6 4.9 1.7 1 1 0 1 1 1 0 YwiC-like protein Proteasome PF00227.21 EPY50334.1 - 4.9e-33 114.0 0.0 1.5e-32 112.4 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit Glyco_transf_20 PF00982.16 EPY50335.1 - 1.9e-139 465.1 0.7 2.6e-139 464.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPY50335.1 - 1.6e-28 99.2 0.0 2.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase TPT PF03151.11 EPY50336.1 - 1.2e-07 31.5 32.4 2.1e-07 30.6 10.5 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EPY50336.1 - 0.002 18.1 34.2 0.022 14.7 8.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EPY50336.1 - 0.57 9.0 30.8 3.7 6.3 21.4 2.1 1 1 0 1 1 1 0 UAA transporter family FLILHELTA PF10306.4 EPY50336.1 - 0.94 9.5 4.3 0.53 10.3 1.1 2.1 2 1 0 2 2 2 0 Hypothetical protein FLILHELTA Actin PF00022.14 EPY50338.1 - 4.5e-119 397.3 0.0 5.6e-119 397.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPY50338.1 - 0.0057 15.2 0.0 0.048 12.2 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein STE2 PF02116.10 EPY50339.1 - 2.8e-53 180.7 29.6 3.6e-53 180.4 20.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF1771 PF08590.5 EPY50340.1 - 6.1e-19 67.7 9.6 1.1e-18 66.9 6.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EPY50340.1 - 7.3e-19 67.7 0.1 1.3e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Smr domain DUF3368 PF11848.3 EPY50340.1 - 0.016 14.7 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Transposase_24 PF03004.9 EPY50340.1 - 0.094 12.5 0.2 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Cut12 PF11500.3 EPY50340.1 - 0.93 9.1 3.2 1.4 8.5 2.2 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Vps23_core PF09454.5 EPY50342.1 - 5.2e-10 38.7 0.1 1.2e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Vps23 core domain XH PF03469.9 EPY50342.1 - 0.038 13.6 3.9 0.12 12.0 2.2 2.0 2 0 0 2 2 2 0 XH domain CCDC155 PF14662.1 EPY50342.1 - 0.074 12.6 8.8 0.15 11.6 6.1 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 ALMT PF11744.3 EPY50342.1 - 0.82 8.2 5.8 3.7 6.1 3.8 1.8 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF423 PF04241.10 EPY50343.1 - 4.9e-23 80.8 0.8 7.7e-23 80.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) APS_kinase PF01583.15 EPY50344.1 - 2.5e-72 241.6 0.0 3.1e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EPY50344.1 - 4.1e-07 29.9 0.0 5.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPY50344.1 - 9.2e-05 23.2 0.0 0.00016 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPY50344.1 - 0.0001 21.6 0.0 0.00011 21.4 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EPY50344.1 - 0.00067 19.9 0.1 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPY50344.1 - 0.0039 16.6 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain 6PF2K PF01591.13 EPY50344.1 - 0.0075 15.3 0.2 0.021 13.8 0.0 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase CPT PF07931.7 EPY50344.1 - 0.0095 15.5 0.4 0.2 11.2 0.3 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 EPY50344.1 - 0.048 13.9 0.0 0.069 13.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EPY50344.1 - 0.086 13.1 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EPY50344.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.18 EPY50344.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L7Ae PF01248.21 EPY50345.1 - 5.1e-27 93.2 0.9 7.5e-27 92.6 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DSPn PF14671.1 EPY50346.1 - 1.6e-52 177.2 0.1 1.9e-50 170.5 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EPY50346.1 - 3.5e-17 62.2 0.0 1.2e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPY50346.1 - 2.3e-07 30.4 0.0 4.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPY50346.1 - 4.2e-05 23.6 0.0 9.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 EPY50346.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EPY50346.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family UcrQ PF02939.11 EPY50347.1 - 5.8e-36 122.1 0.3 6.7e-36 121.9 0.2 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EPY50347.1 - 0.0095 16.0 0.0 0.014 15.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2741) RNase_T PF00929.19 EPY50348.1 - 2e-16 60.6 0.0 3.7e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EPY50348.1 - 0.00018 21.0 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Band_7 PF01145.20 EPY50349.1 - 5.4e-25 88.3 10.1 9e-25 87.6 4.6 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 EPY50349.1 - 0.025 14.0 1.5 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus PTPA PF03095.10 EPY50350.1 - 1.9e-110 368.7 0.0 2.2e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1713 PF08213.6 EPY50351.1 - 8.1e-13 47.7 22.1 1.1e-12 47.2 15.3 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EPY50351.1 - 0.00018 21.4 0.3 0.00031 20.7 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial protein Pet20 Prp19_bind PF06991.6 EPY50352.1 - 2e-66 224.0 27.3 2e-66 224.0 18.9 2.6 2 1 1 3 3 3 1 Splicing factor, Prp19-binding domain IGF2_C PF08365.6 EPY50352.1 - 0.26 11.0 3.6 0.35 10.6 1.5 2.0 1 1 0 1 1 1 0 Insulin-like growth factor II E-peptide FAM176 PF14851.1 EPY50352.1 - 0.5 10.0 0.0 0.5 10.0 0.0 3.5 1 1 3 4 4 4 0 FAM176 family Myb_DNA-bind_6 PF13921.1 EPY50353.1 - 2.1e-20 72.5 10.6 3.5e-11 43.0 0.1 4.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPY50353.1 - 3e-19 68.7 3.7 1e-08 35.1 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EPY50353.1 - 0.086 12.9 5.1 0.41 10.8 0.0 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rad60-SLD PF11976.3 EPY50353.1 - 0.087 12.5 0.0 5.8 6.6 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Sec23_trunk PF04811.10 EPY50354.1 - 4.9e-75 252.0 0.0 9.5e-75 251.0 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPY50354.1 - 7e-22 76.8 0.4 7e-22 76.8 0.3 2.3 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPY50354.1 - 1.2e-17 64.1 0.0 2.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPY50354.1 - 3.8e-14 51.9 5.4 7.3e-14 51.0 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPY50354.1 - 1.7e-08 33.9 0.0 4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Nop53 PF07767.6 EPY50355.1 - 2.4e-85 286.8 31.7 3.1e-85 286.5 22.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF382 PF04037.8 EPY50356.1 - 2.9e-59 198.4 0.1 2.9e-59 198.4 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.11 EPY50356.1 - 1.6e-24 85.0 3.5 3.3e-24 84.0 2.4 1.6 1 0 0 1 1 1 1 PSP PI-PLC-X PF00388.14 EPY50357.1 - 2e-59 199.1 0.0 4e-59 198.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EPY50357.1 - 9.1e-38 128.8 0.1 2.1e-37 127.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EPY50357.1 - 6.7e-10 38.8 2.7 2.8e-09 36.8 0.4 2.9 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EPY50357.1 - 1.9e-08 33.9 0.0 5.7e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.1 EPY50357.1 - 0.022 14.6 1.0 7.8 6.6 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EPY50357.1 - 0.035 14.2 0.9 0.14 12.3 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_10 PF14788.1 EPY50357.1 - 0.038 13.6 3.8 0.038 13.6 0.2 2.9 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 EPY50357.1 - 0.11 12.0 0.1 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Lge1 PF11488.3 EPY50358.1 - 0.0022 18.1 0.1 0.0039 17.3 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 DUF1295 PF06966.7 EPY50359.1 - 0.0094 15.2 0.0 0.01 15.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1385 PF07136.6 EPY50360.1 - 0.021 13.9 1.5 0.15 11.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1385) Bac_export_2 PF01312.14 EPY50360.1 - 0.044 12.6 1.7 0.053 12.4 1.2 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Cohesin_load PF10345.4 EPY50360.1 - 0.075 11.2 0.5 0.11 10.6 0.3 1.3 1 1 0 1 1 1 0 Cohesin loading factor DUF4064 PF13273.1 EPY50360.1 - 0.19 11.8 2.2 0.27 11.3 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) SLAC1 PF03595.12 EPY50360.1 - 1.3 7.5 10.4 0.093 11.3 1.8 2.0 1 1 1 2 2 2 0 Voltage-dependent anion channel DUF3753 PF12575.3 EPY50360.1 - 2 8.2 9.4 2.8 7.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Abi PF02517.11 EPY50360.1 - 2.5 8.3 5.4 7.9 6.6 3.7 1.8 1 1 0 1 1 1 0 CAAX protease self-immunity AsiA PF09010.5 EPY50361.1 - 0.072 12.9 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Anti-Sigma Factor A COMP PF11598.3 EPY50361.1 - 0.13 12.3 0.3 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein ABC_tran PF00005.22 EPY50362.1 - 2.3e-18 66.8 0.0 8.5e-18 64.9 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPY50362.1 - 4.7e-12 46.4 0.3 3.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPY50362.1 - 1.3e-06 27.9 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPY50362.1 - 3.7e-06 26.2 0.0 0.05 12.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EPY50362.1 - 4.2e-05 22.9 0.1 8.7e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EPY50362.1 - 0.00016 21.2 0.1 0.00028 20.4 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain DUF258 PF03193.11 EPY50362.1 - 0.00079 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRP54 PF00448.17 EPY50362.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SMC_N PF02463.14 EPY50362.1 - 0.0028 16.9 0.1 0.95 8.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPY50362.1 - 0.0029 18.3 0.0 0.0063 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EPY50362.1 - 0.0061 16.5 0.4 0.02 14.8 0.1 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EPY50362.1 - 0.0077 15.3 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 EPY50362.1 - 0.0077 15.7 0.1 0.023 14.1 0.0 1.7 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EPY50362.1 - 0.0085 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY50362.1 - 0.014 15.3 2.5 0.03 14.3 1.7 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.3 EPY50362.1 - 0.022 12.1 0.2 0.033 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_28 PF13521.1 EPY50362.1 - 0.027 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPY50362.1 - 0.044 13.3 0.2 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EPY50362.1 - 0.048 13.8 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY50362.1 - 0.055 13.3 0.3 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EPY50362.1 - 0.063 12.9 0.3 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EPY50362.1 - 0.087 12.5 0.1 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EPY50362.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 1 0 Miro-like protein ArgK PF03308.11 EPY50362.1 - 0.11 11.2 0.1 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 EPY50362.1 - 0.13 12.5 0.5 0.6 10.3 0.3 2.3 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EPY50362.1 - 0.14 11.6 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EPY50362.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FH2 PF02181.18 EPY50363.1 - 2.2e-72 244.0 4.4 5.3e-72 242.7 3.0 1.7 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EPY50363.1 - 6.2e-36 123.5 1.2 6.2e-36 123.5 0.8 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EPY50363.1 - 9e-07 28.4 0.3 9e-07 28.4 0.2 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain Pkinase PF00069.20 EPY50364.1 - 1.3e-36 126.1 0.0 7.5e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50364.1 - 5.4e-18 65.0 0.0 3e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase IL7 PF01415.11 EPY50364.1 - 0.041 13.5 0.3 0.14 11.7 0.2 1.9 1 0 0 1 1 1 0 Interleukin 7/9 family HALZ PF02183.13 EPY50364.1 - 0.053 13.2 1.4 0.12 12.1 1.0 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Hus1 PF04005.7 EPY50365.1 - 2.4e-92 309.0 0.3 2.7e-92 308.8 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein UPF0061 PF02696.9 EPY50366.1 - 1.2e-111 373.4 0.0 1.5e-111 373.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Cofilin_ADF PF00241.15 EPY50367.1 - 2.4e-44 150.2 0.2 2.7e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ERG4_ERG24 PF01222.12 EPY50368.1 - 1.2e-177 590.8 18.4 1.3e-177 590.6 12.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Brr6_like_C_C PF10104.4 EPY50369.1 - 0.57 9.6 6.6 0.51 9.8 2.5 2.0 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Baculo_PEP_C PF04513.7 EPY50370.1 - 0.00013 21.8 6.6 0.0013 18.5 2.8 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.3 EPY50370.1 - 0.011 15.8 0.7 0.12 12.4 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) HutP PF09021.6 EPY50370.1 - 0.14 12.3 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 HutP Peptidase_M18 PF02127.10 EPY50371.1 - 5.5e-176 585.2 0.0 6.3e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EPY50371.1 - 3e-05 22.9 0.0 0.00039 19.2 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase RabGAP-TBC PF00566.13 EPY50372.1 - 3.1e-34 118.3 15.5 1.3e-33 116.3 10.8 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EPY50372.1 - 2.7e-09 36.6 0.0 0.00014 21.2 0.0 3.6 3 0 0 3 3 3 3 Domain of unknown function (DUF3548) DUF2011 PF09428.5 EPY50373.1 - 2.8e-16 59.5 11.3 5.4e-16 58.6 7.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF604 PF04646.7 EPY50373.1 - 0.17 11.0 0.3 0.24 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF604 FA_hydroxylase PF04116.8 EPY50375.1 - 2.5e-16 60.0 21.4 2.5e-16 60.0 14.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sprouty PF05210.8 EPY50375.1 - 0.23 11.5 0.8 23 5.0 0.0 2.2 2 0 0 2 2 2 0 Sprouty protein (Spry) Zeta_toxin PF06414.7 EPY50376.1 - 5.8e-06 25.5 0.0 9.5e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EPY50376.1 - 1.9e-05 24.7 0.0 0.0001 22.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EPY50376.1 - 0.00011 22.9 0.0 0.00021 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EPY50376.1 - 0.00015 20.5 0.0 0.0002 20.1 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain ABC_tran PF00005.22 EPY50376.1 - 0.00042 20.6 0.0 0.00087 19.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 EPY50376.1 - 0.0013 18.3 0.4 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain PRK PF00485.13 EPY50376.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 EPY50376.1 - 0.0016 17.4 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_18 PF13238.1 EPY50376.1 - 0.002 18.4 0.1 0.0035 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EPY50376.1 - 0.002 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_14 PF13173.1 EPY50376.1 - 0.0062 16.4 0.0 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPY50376.1 - 0.014 15.0 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EPY50376.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 EPY50376.1 - 0.025 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EPY50376.1 - 0.033 14.5 0.0 0.074 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 EPY50376.1 - 0.035 13.0 0.1 0.39 9.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.9 EPY50376.1 - 0.038 13.7 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EPY50376.1 - 0.043 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EPY50376.1 - 0.047 13.5 0.1 0.13 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EPY50376.1 - 0.047 13.2 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 EPY50376.1 - 0.05 12.7 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EPY50376.1 - 0.051 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPY50376.1 - 0.061 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EPY50376.1 - 0.069 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EPY50376.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.12 EPY50376.1 - 0.1 11.9 0.1 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase T2SE PF00437.15 EPY50376.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EPY50376.1 - 0.15 11.7 0.2 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 NTPase S-AdoMet_synt_C PF02773.11 EPY50377.1 - 4.7e-74 246.6 0.1 7.8e-74 245.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EPY50377.1 - 1.3e-46 157.3 0.0 2.9e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EPY50377.1 - 3.2e-44 149.2 0.3 6.9e-44 148.1 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain SGL PF08450.7 EPY50377.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region AdoMet_Synthase PF01941.14 EPY50377.1 - 0.11 10.9 0.4 0.48 8.8 0.1 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ABC_tran PF00005.22 EPY50378.1 - 2.1e-32 112.2 0.0 1.5e-17 64.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 EPY50378.1 - 5.3e-14 51.5 4.0 1.3e-13 50.2 2.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EPY50378.1 - 3.1e-11 43.7 2.9 0.091 12.7 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EPY50378.1 - 2.9e-10 39.7 2.6 0.0049 16.1 0.3 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EPY50378.1 - 4.2e-08 32.4 3.2 4.2e-08 32.4 2.2 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_15 PF13175.1 EPY50378.1 - 1.8e-06 27.3 0.1 1.4 7.9 0.0 4.0 4 0 0 4 4 4 2 AAA ATPase domain Fer4_6 PF12837.2 EPY50378.1 - 1e-05 25.1 2.1 1e-05 25.1 1.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 EPY50378.1 - 1.3e-05 24.6 0.5 0.062 12.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPY50378.1 - 1.6e-05 25.0 0.0 0.0048 17.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPY50378.1 - 3.1e-05 24.1 0.1 0.025 14.7 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPY50378.1 - 6.5e-05 22.1 1.0 0.15 11.2 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 EPY50378.1 - 0.00023 20.8 2.1 0.015 14.9 0.1 2.3 2 0 0 2 2 2 1 NACHT domain Fer4_21 PF14697.1 EPY50378.1 - 0.00027 20.7 10.7 0.00052 19.8 7.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 EPY50378.1 - 0.00029 20.2 0.0 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EPY50378.1 - 0.00037 20.8 0.4 0.036 14.4 0.2 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EPY50378.1 - 0.00044 20.7 0.2 0.031 14.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 EPY50378.1 - 0.00045 19.8 0.5 0.013 15.0 0.1 2.7 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_2 PF12797.2 EPY50378.1 - 0.0006 19.5 12.2 0.00064 19.4 1.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 EPY50378.1 - 0.0009 19.5 1.6 0.0009 19.5 1.1 2.4 1 1 2 3 3 3 2 4Fe-4S dicluster domain AAA_16 PF13191.1 EPY50378.1 - 0.0019 18.2 0.0 0.46 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_9 PF13187.1 EPY50378.1 - 0.0021 18.2 2.0 0.0021 18.2 1.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Rad17 PF03215.10 EPY50378.1 - 0.0027 16.4 0.0 0.17 10.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_10 PF13237.1 EPY50378.1 - 0.0032 17.2 1.4 0.0032 17.2 1.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EPY50378.1 - 0.0035 18.0 0.1 0.0035 18.0 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 EPY50378.1 - 0.0061 17.0 5.0 0.0061 17.0 3.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.1 EPY50378.1 - 0.0079 16.0 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 EPY50378.1 - 0.0081 15.6 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E RNA_helicase PF00910.17 EPY50378.1 - 0.012 15.7 0.1 2.7 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EPY50378.1 - 0.015 16.1 0.5 7.5 7.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EPY50378.1 - 0.016 15.1 0.1 0.75 9.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EPY50378.1 - 0.018 14.9 0.0 5.5 6.9 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 EPY50378.1 - 0.018 14.1 0.1 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 KaiC Fer4_8 PF13183.1 EPY50378.1 - 0.021 14.8 8.1 0.048 13.7 5.6 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_5 PF07728.9 EPY50378.1 - 0.022 14.4 0.3 1.3 8.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EPY50378.1 - 0.022 14.2 3.1 0.35 10.2 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_17 PF13534.1 EPY50378.1 - 0.026 14.8 0.1 0.026 14.8 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 EPY50378.1 - 0.038 12.8 0.5 6 5.6 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain AAA_14 PF13173.1 EPY50378.1 - 0.05 13.5 0.1 5 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 EPY50378.1 - 0.066 12.9 1.9 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EPY50378.1 - 0.081 11.8 0.2 4.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.13 EPY50378.1 - 0.092 11.7 0.1 0.68 8.8 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_18 PF13238.1 EPY50378.1 - 0.1 12.9 0.0 7.7 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EPY50378.1 - 0.11 12.2 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Fer4_4 PF12800.2 EPY50378.1 - 0.14 12.5 13.5 0.044 14.1 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_24 PF13479.1 EPY50378.1 - 0.15 11.6 2.3 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPY50378.1 - 0.17 11.4 0.3 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EPY50378.1 - 0.39 10.4 2.4 17 5.0 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 EPY50378.1 - 0.47 9.8 2.9 17 4.6 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 EPY50378.1 - 0.49 10.3 1.8 5.1 7.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain Fer4_15 PF13459.1 EPY50378.1 - 5.1 7.7 8.2 0.11 13.0 0.7 2.0 2 0 0 2 2 1 0 4Fe-4S single cluster domain RINGv PF12906.2 EPY50379.1 - 1e-15 57.4 13.8 1.8e-15 56.6 9.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EPY50379.1 - 4 7.3 12.7 7.3 6.5 8.8 1.4 1 0 0 1 1 1 0 Ring finger domain Med7 PF05983.6 EPY50380.1 - 4.7e-47 159.7 4.9 4e-32 111.2 1.0 2.2 2 0 0 2 2 2 2 MED7 protein Lyase_1 PF00206.15 EPY50381.1 - 2.3e-23 82.8 0.0 3.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EPY50381.1 - 2e-14 53.3 0.0 5.1e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 EPY50381.1 - 0.018 14.9 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 Anti-Sigma Factor A Med18 PF09637.5 EPY50381.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Med18 protein LON PF02190.11 EPY50382.1 - 1.9e-17 63.6 0.1 8.2e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EPY50382.1 - 1.2e-12 47.5 22.4 9.9e-10 38.2 6.6 3.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY50382.1 - 1.1e-10 41.1 20.0 3.9e-09 36.1 6.3 3.1 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EPY50382.1 - 2.1e-10 40.1 13.7 2.7e-08 33.3 3.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPY50382.1 - 2.7e-10 39.9 20.4 1.8e-05 24.4 3.4 3.7 3 0 0 3 3 3 3 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EPY50382.1 - 4.1e-10 39.1 20.3 1.2e-08 34.5 5.9 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY50382.1 - 1.9e-08 33.9 7.6 1.9e-08 33.9 5.3 2.8 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPY50382.1 - 3.3e-06 26.7 8.9 0.00033 20.2 1.4 3.1 2 1 0 2 2 2 2 RING-type zinc-finger U-box PF04564.10 EPY50382.1 - 0.0002 21.2 0.1 0.0053 16.6 0.0 3.2 3 0 0 3 3 3 1 U-box domain zf-rbx1 PF12678.2 EPY50382.1 - 0.00063 19.8 2.5 0.0021 18.1 1.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EPY50382.1 - 0.027 14.0 14.0 0.29 10.7 4.7 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain Rsbr_N PF08678.5 EPY50382.1 - 0.055 13.3 2.2 1.7 8.5 0.5 2.2 2 0 0 2 2 2 0 Rsbr N terminal zf-RING_6 PF14835.1 EPY50382.1 - 1.1 9.0 12.1 0.1 12.3 3.4 2.7 2 1 1 3 3 3 0 zf-RING of BARD1-type protein PX PF00787.19 EPY50383.1 - 6.4e-18 64.5 4.8 1.1e-17 63.8 0.6 2.7 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EPY50383.1 - 0.003 16.8 7.5 0.055 12.7 0.3 2.7 2 1 0 2 2 2 2 Vps5 C terminal like Alk_phosphatase PF00245.15 EPY50384.1 - 1.3e-98 330.4 0.0 1.6e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EPY50384.1 - 0.0094 15.3 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Metallophos PF00149.23 EPY50385.1 - 5.1e-38 130.4 0.0 8.1e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EPY50385.1 - 8.2e-26 89.4 9.8 2e-19 69.0 1.3 2.5 1 1 0 2 2 2 2 TPR repeat PPP5 PF08321.7 EPY50385.1 - 9e-26 89.7 0.1 2.3e-25 88.4 0.1 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.12 EPY50385.1 - 4.2e-18 63.7 9.0 7.9e-06 25.4 0.6 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPY50385.1 - 1.5e-17 62.3 10.6 1.8e-06 27.2 0.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPY50385.1 - 1.6e-09 37.1 7.4 0.0025 17.8 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPY50385.1 - 2.8e-09 36.7 1.8 0.00026 21.3 0.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY50385.1 - 8.4e-09 35.8 5.8 1.1e-06 29.1 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPY50385.1 - 3e-07 29.7 6.0 0.043 13.5 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPY50385.1 - 9e-07 29.1 4.6 0.028 14.7 0.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.1 EPY50385.1 - 0.00011 21.3 1.0 0.069 12.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50385.1 - 0.00012 21.9 5.4 0.0088 15.9 0.4 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPY50385.1 - 0.00085 19.1 0.6 0.11 12.4 0.1 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPY50385.1 - 0.0014 18.9 1.2 0.28 11.7 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPY50385.1 - 0.0085 15.8 0.3 7.5 6.6 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EPY50385.1 - 0.14 12.2 4.9 3.7 7.7 0.5 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 3Beta_HSD PF01073.14 EPY50386.1 - 5e-68 228.8 0.0 5.9e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPY50386.1 - 9.4e-33 113.5 0.0 1.4e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPY50386.1 - 1.8e-16 59.8 0.0 2.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPY50386.1 - 2.6e-14 52.7 0.1 1.5e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPY50386.1 - 4.5e-12 46.3 0.0 1e-11 45.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPY50386.1 - 4.1e-10 39.0 0.0 8.6e-10 37.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPY50386.1 - 1.5e-05 25.0 0.0 3.7e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY50386.1 - 9.1e-05 22.2 0.0 0.00036 20.2 0.0 1.8 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 EPY50386.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EPY50386.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase FCD PF07729.7 EPY50386.1 - 0.074 13.3 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 FCD domain Pyr_redox_2 PF07992.9 EPY50387.1 - 6.1e-25 88.2 0.1 7.7e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPY50387.1 - 7.1e-17 61.5 0.1 1e-14 54.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPY50387.1 - 3e-08 33.9 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPY50387.1 - 5.3e-06 25.6 0.0 0.00014 21.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EPY50387.1 - 3.6e-05 23.9 0.0 0.015 15.5 0.0 3.1 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EPY50387.1 - 0.00024 21.2 0.0 0.36 10.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EPY50387.1 - 0.00047 19.3 0.1 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPY50387.1 - 0.00056 18.9 0.5 0.81 8.5 0.2 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPY50387.1 - 0.0013 18.7 0.4 0.082 12.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPY50387.1 - 0.0027 16.6 1.9 0.095 11.5 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 EPY50387.1 - 0.0057 15.6 0.1 2.1 7.2 0.0 3.1 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EPY50387.1 - 0.0093 14.8 1.0 0.32 9.7 0.1 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A HI0933_like PF03486.9 EPY50387.1 - 0.062 11.7 0.1 0.13 10.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EPY50387.1 - 0.1 11.1 0.4 0.22 10.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Nop14 PF04147.7 EPY50388.1 - 2.6e-228 760.0 35.0 4.9e-228 759.1 24.3 1.3 1 1 0 1 1 1 1 Nop14-like family RhoGAP PF00620.22 EPY50389.1 - 2e-36 124.9 0.1 4.1e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EPY50389.1 - 4.1e-27 94.0 39.6 8.3e-13 48.1 4.8 5.5 5 0 0 5 5 5 4 LIM domain Alg6_Alg8 PF03155.10 EPY50390.1 - 7.3e-162 539.4 43.4 9.2e-162 539.1 30.1 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RRM_6 PF14259.1 EPY50391.1 - 5.9e-14 51.7 0.1 0.0065 16.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY50391.1 - 4.1e-10 39.1 0.2 0.00097 18.7 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syja_N PF02383.13 EPY50392.1 - 3.4e-86 288.9 0.0 1.1e-85 287.1 0.0 1.8 2 0 0 2 2 2 1 SacI homology domain PolyA_pol PF01743.15 EPY50393.1 - 1e-25 90.3 0.0 1.9e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EPY50393.1 - 6.7e-10 38.3 0.0 1.7e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EPY50393.1 - 0.026 14.3 0.5 0.19 11.5 0.3 2.3 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DEAD PF00270.24 EPY50394.1 - 3.7e-45 153.4 0.0 6.6e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPY50394.1 - 6.3e-25 86.5 0.2 1.3e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPY50394.1 - 1.1e-21 76.4 0.0 2.8e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EPY50394.1 - 0.0047 16.8 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DHC_N1 PF08385.7 EPY50395.1 - 1e-113 380.7 19.6 1e-113 380.7 13.6 4.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EPY50395.1 - 2.5e-74 250.2 4.6 2.5e-74 250.2 3.2 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EPY50395.1 - 4.3e-53 180.2 0.3 1.4e-52 178.5 0.0 2.1 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 EPY50395.1 - 1.4e-25 89.6 0.0 8.4e-12 44.9 0.0 6.2 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.10 EPY50395.1 - 5.2e-22 77.6 0.2 5.2e-22 77.6 0.2 1.5 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 EPY50395.1 - 3.8e-21 75.2 5.6 7.2e-21 74.3 3.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.1 EPY50395.1 - 3e-12 46.7 0.2 0.00062 19.9 0.0 6.1 5 0 0 5 5 5 2 AAA domain AAA_9 PF12781.2 EPY50395.1 - 5.1e-11 41.8 0.2 5.1e-11 41.8 0.1 2.6 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA PF00004.24 EPY50395.1 - 7.7e-08 32.6 0.0 0.045 13.9 0.0 4.5 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPY50395.1 - 1.1e-05 26.2 0.3 0.36 11.6 0.0 4.9 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EPY50395.1 - 1.8e-05 24.8 0.0 0.8 9.6 0.0 4.8 5 0 0 5 5 4 1 AAA ATPase domain RNA_helicase PF00910.17 EPY50395.1 - 0.00024 21.2 0.0 4.9 7.3 0.0 4.1 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.1 EPY50395.1 - 0.0018 17.9 0.1 0.97 9.2 0.1 3.1 3 0 0 3 3 3 1 Part of AAA domain T2SE PF00437.15 EPY50395.1 - 0.0023 16.9 0.0 0.09 11.6 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.1 EPY50395.1 - 0.0055 17.0 0.8 17 5.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 EPY50395.1 - 0.0069 16.2 0.0 1.3 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EPY50395.1 - 0.05 13.0 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPY50395.1 - 0.057 13.0 0.1 10 5.6 0.0 3.2 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.7 EPY50395.1 - 0.07 12.2 0.0 19 4.2 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 EPY50395.1 - 0.14 12.1 0.0 35 4.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EPY50395.1 - 0.36 10.2 0.0 8.6 5.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EPY50395.1 - 0.54 9.3 0.1 8.2 5.5 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF917 PF06032.7 EPY50395.1 - 5.6 5.4 0.0 8.3 4.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) HEAT_2 PF13646.1 EPY50396.1 - 1.4e-35 121.4 0.0 2.1e-14 53.5 0.0 4.0 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 EPY50396.1 - 3.8e-25 85.7 0.0 0.00019 21.5 0.0 7.0 7 0 0 7 7 7 6 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EPY50396.1 - 4.2e-09 36.6 0.0 0.21 12.0 0.0 4.7 3 2 2 5 5 5 4 HEAT-like repeat HEAT PF02985.17 EPY50396.1 - 9.8e-08 31.4 1.4 0.87 9.8 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat DUF310 PF03750.8 EPY50396.1 - 0.027 14.6 0.1 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF310) Aconitase_B_N PF11791.3 EPY50396.1 - 0.052 13.3 0.1 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Aconitate B N-terminal domain Vitellogenin_N PF01347.17 EPY50396.1 - 0.092 10.9 0.1 4.9 5.2 0.0 2.8 1 1 0 2 2 2 0 Lipoprotein amino terminal region Ribonuclease_P PF00825.13 EPY50397.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease P tRNA_bind PF01588.15 EPY50398.1 - 1e-26 92.5 0.1 2.1e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EPY50398.1 - 0.00011 22.6 0.0 0.00011 22.6 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2201_N PF13203.1 EPY50398.1 - 0.09 11.9 1.8 0.13 11.3 1.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 EPY50398.1 - 0.49 9.7 13.3 0.79 9.0 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RP-C_C PF11800.3 EPY50398.1 - 1.1 8.8 6.2 2.7 7.6 4.3 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.7 EPY50398.1 - 1.9 8.3 12.6 3.5 7.4 8.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tom37_C PF11801.3 EPY50398.1 - 8.1 6.2 13.2 1.8 8.3 0.5 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain Cornichon PF03311.9 EPY50399.1 - 3.6e-44 149.9 10.8 3.9e-44 149.8 7.5 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 EPY50399.1 - 8.6 5.8 9.7 17 4.8 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Tubulin_3 PF14881.1 EPY50400.1 - 5.8e-35 120.3 0.0 9.6e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EPY50400.1 - 1.2e-19 70.4 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EPY50400.1 - 0.053 13.3 0.0 0.26 11.0 0.0 2.1 2 1 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain FNIP_N PF14636.1 EPY50401.1 - 0.00039 20.9 0.2 0.0062 17.0 0.0 4.8 3 2 1 4 4 4 2 Folliculin-interacting protein N-terminus DUF2408 PF10303.4 EPY50402.1 - 1.5e-61 206.3 10.3 3.8e-34 117.6 0.1 5.4 3 3 2 5 5 5 4 Protein of unknown function (DUF2408) TelA PF05816.6 EPY50402.1 - 0.047 12.3 0.7 0.089 11.4 0.1 1.8 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Vps51 PF08700.6 EPY50402.1 - 0.058 13.2 3.7 10 6.0 0.4 4.2 4 0 0 4 4 4 0 Vps51/Vps67 Laminin_II PF06009.7 EPY50402.1 - 0.22 11.2 6.6 1.1 8.9 0.0 4.1 4 1 1 5 5 5 0 Laminin Domain II DegS PF05384.6 EPY50402.1 - 3.3 6.9 8.3 0.69 9.1 0.1 3.3 4 0 0 4 4 4 0 Sensor protein DegS DUF3887 PF13026.1 EPY50403.1 - 0.0042 17.3 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3887) Phage_int_SAM_4 PF13495.1 EPY50403.1 - 0.065 13.5 0.4 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Porin_3 PF01459.17 EPY50404.1 - 1e-57 195.5 3.4 1.2e-57 195.3 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin TIP_N PF12457.3 EPY50405.1 - 0.044 13.8 3.0 0.044 13.8 2.1 2.0 1 1 1 2 2 2 0 Tuftelin interacting protein N terminal Mre11_DNA_bind PF04152.9 EPY50405.1 - 0.21 11.4 9.0 0.16 11.7 5.5 1.4 1 1 0 1 1 1 0 Mre11 DNA-binding presumed domain DUF1570 PF07607.6 EPY50405.1 - 0.63 10.0 2.8 0.55 10.2 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1570) zf-H2C2_2 PF13465.1 EPY50407.1 - 3.9e-09 36.3 4.3 5.8e-06 26.3 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPY50407.1 - 7.2e-06 26.0 16.6 9.5e-06 25.6 0.1 4.4 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY50407.1 - 8.4e-05 22.6 0.1 8.4e-05 22.6 0.1 3.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 EPY50407.1 - 0.022 14.9 0.1 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EPY50407.1 - 0.026 14.4 0.2 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EPY50407.1 - 0.048 13.7 3.4 5.7 7.1 0.4 2.9 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF3166 PF11365.3 EPY50407.1 - 0.12 12.8 1.3 2.5 8.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Adenylsucc_synt PF00709.16 EPY50408.1 - 6.3e-167 555.5 0.0 7.2e-167 555.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Orn_Arg_deC_N PF02784.11 EPY50409.1 - 2.1e-73 246.6 0.0 2.8e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EPY50409.1 - 3.9e-36 123.3 0.1 9e-36 122.1 0.1 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PNPOx_C PF10590.4 EPY50410.1 - 4.5e-17 61.2 1.8 9.4e-17 60.2 0.7 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EPY50410.1 - 9e-15 54.4 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EPY50410.1 - 0.011 16.0 0.5 0.022 15.0 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DDE_1 PF03184.14 EPY50412.1 - 4e-55 186.3 2.0 6.4e-55 185.6 0.6 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPY50412.1 - 1.1e-16 60.4 0.8 1.1e-16 60.4 0.5 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain PPR_2 PF13041.1 EPY50413.1 - 7e-37 125.1 17.8 1.6e-11 44.0 0.0 12.4 9 1 4 13 13 13 7 PPR repeat family PPR_3 PF13812.1 EPY50413.1 - 1.6e-32 109.0 2.5 0.00028 20.9 0.0 12.4 13 0 0 13 13 13 7 Pentatricopeptide repeat domain PPR PF01535.15 EPY50413.1 - 4.5e-25 85.8 11.9 0.0001 22.0 0.0 11.4 13 1 0 13 13 13 5 PPR repeat PPR_1 PF12854.2 EPY50413.1 - 1.1e-20 72.8 2.5 2.5e-06 26.8 0.0 9.1 11 0 0 11 11 11 4 PPR repeat RPM2 PF08579.6 EPY50413.1 - 0.00027 21.0 1.2 0.01 15.9 0.1 3.7 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) COX5A PF02284.11 EPY50413.1 - 0.00069 19.5 1.6 12 5.8 0.0 4.9 4 1 1 5 5 5 1 Cytochrome c oxidase subunit Va TPR_19 PF14559.1 EPY50413.1 - 0.0088 16.3 0.1 29 5.0 0.0 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY50413.1 - 0.031 14.7 0.7 28 5.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY50413.1 - 0.13 12.9 0.0 78 4.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1237 PF06824.6 EPY50414.1 - 2.5e-177 589.7 0.0 2.9e-177 589.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) RNase_H2_suC PF08615.6 EPY50415.1 - 2.9e-21 75.7 0.0 3.4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CLTH PF10607.4 EPY50417.1 - 8.2e-35 119.6 1.6 9.9e-35 119.3 1.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPY50417.1 - 0.0029 17.3 0.2 0.0074 16.0 0.0 1.9 2 0 0 2 2 2 1 LisH DnaB_C PF03796.10 EPY50417.1 - 0.085 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Rad4 PF03835.10 EPY50418.1 - 4e-29 100.8 0.0 7.3e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EPY50418.1 - 3.7e-24 84.2 0.0 9.1e-24 82.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EPY50418.1 - 5.2e-21 73.9 0.6 4.9e-19 67.6 0.2 2.5 2 0 0 2 2 2 2 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EPY50418.1 - 1.4e-10 41.3 1.4 2.8e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EPY50418.1 - 0.0023 18.1 0.0 0.006 16.7 0.0 1.8 1 1 0 1 1 1 1 Transglutaminase-like superfamily Cellulase PF00150.13 EPY50419.1 - 5.5e-11 42.1 0.2 5.5e-11 42.1 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Mito_carr PF00153.22 EPY50421.1 - 6.7e-49 163.5 3.8 4.5e-18 64.7 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein F-actin_cap_A PF01267.12 EPY50422.1 - 2.4e-63 213.7 5.2 2.6e-63 213.6 3.6 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Med1 PF10744.4 EPY50422.1 - 0.0071 15.1 0.1 0.024 13.4 0.0 1.7 1 1 1 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 SIMPL PF04402.9 EPY50422.1 - 0.42 10.4 4.6 7.1 6.4 3.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Peptidase_M24 PF00557.19 EPY50423.1 - 6e-47 159.9 0.0 1.4e-46 158.6 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EPY50423.1 - 1.8e-24 85.6 0.0 4.2e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Sdh5 PF03937.11 EPY50424.1 - 6.5e-25 86.6 0.7 8.5e-25 86.2 0.5 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase G-gamma PF00631.17 EPY50424.1 - 0.062 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 GGL domain TTL PF03133.10 EPY50425.1 - 9.8e-62 208.5 0.5 1.5e-61 207.9 0.4 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EPY50425.1 - 0.001 18.8 0.0 0.057 13.1 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EPY50425.1 - 0.006 15.4 0.0 0.013 14.2 0.0 1.6 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 EPY50425.1 - 0.0079 16.0 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPY50425.1 - 0.024 13.4 0.0 2.2 6.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPY50425.1 - 0.07 12.5 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus WD40 PF00400.27 EPY50426.1 - 2.6e-17 61.9 18.4 0.00019 21.1 0.1 6.7 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EPY50426.1 - 0.00038 20.2 0.1 0.25 11.0 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPY50426.1 - 0.0023 15.8 0.0 0.65 7.7 0.0 2.1 1 1 0 2 2 2 2 IKI3 family Acetyltransf_4 PF13420.1 EPY50427.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HECT PF00632.20 EPY50428.1 - 5.9e-84 281.9 0.0 1.3e-83 280.8 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UNC45-central PF11701.3 EPY50428.1 - 0.086 12.4 3.7 0.69 9.5 0.0 2.9 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central TFIIA PF03153.8 EPY50428.1 - 1.3 8.8 28.4 2.8 7.7 19.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EPY50428.1 - 1.5 7.2 33.3 2.8 6.3 23.1 1.4 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EPY50428.1 - 3.4 6.8 39.1 6.4 5.9 27.1 1.3 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.1 EPY50428.1 - 8.7 5.7 15.5 19 4.6 10.8 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Zds_C PF08632.5 EPY50429.1 - 4.2e-31 106.0 0.7 8.4e-31 105.1 0.5 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term PH PF00169.24 EPY50430.1 - 1.1e-05 25.5 0.5 7.7e-05 22.8 0.1 2.6 3 1 0 3 3 3 1 PH domain DUF4611 PF15387.1 EPY50430.1 - 0.012 15.7 0.2 0.034 14.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 EPY50430.1 - 0.024 14.2 1.0 0.024 14.2 0.7 2.6 3 1 1 4 4 4 0 Sigma-70, non-essential region PV_NSP1 PF12433.3 EPY50430.1 - 0.061 13.4 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein 1 MOZ_SAS PF01853.13 EPY50431.1 - 2.7e-89 297.4 2.7 3.7e-89 296.9 1.9 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EPY50431.1 - 1.2e-19 69.7 1.6 3e-19 68.4 1.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EPY50431.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Chromo PF00385.19 EPY50431.1 - 0.034 13.8 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Acetyltransf_7 PF13508.1 EPY50431.1 - 0.049 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease PF00324.16 EPY50432.1 - 3e-130 434.7 36.6 3.4e-130 434.5 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY50432.1 - 3.7e-36 124.5 43.3 4.9e-36 124.1 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease GST_N_3 PF13417.1 EPY50433.1 - 4.2e-15 55.7 0.0 6.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPY50433.1 - 3.3e-14 52.6 0.0 7.5e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPY50433.1 - 6.9e-14 51.7 0.3 1.6e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPY50433.1 - 9.2e-07 28.7 0.0 2.2e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Melibiase PF02065.13 EPY50434.1 - 4.5e-43 147.4 0.1 3.7e-23 81.8 0.0 2.1 1 1 1 2 2 2 2 Melibiase DAO PF01266.19 EPY50435.1 - 3.1e-50 171.0 0.0 4.2e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPY50435.1 - 5.8e-12 45.1 1.3 1.8e-11 43.5 0.9 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPY50435.1 - 4.3e-09 35.9 1.2 1.7e-05 24.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EPY50435.1 - 0.00015 20.7 0.7 0.0025 16.7 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EPY50435.1 - 0.00068 18.2 0.1 0.0014 17.1 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EPY50435.1 - 0.0014 17.8 0.4 0.28 10.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family 3HCDH_N PF02737.13 EPY50435.1 - 0.0015 18.1 1.3 0.0072 15.9 0.9 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EPY50435.1 - 0.0017 18.2 0.4 0.012 15.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPY50435.1 - 0.0089 15.1 0.4 0.021 13.8 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPY50435.1 - 0.069 13.1 0.3 0.23 11.5 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPY50435.1 - 0.078 11.8 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein RICTOR_M PF14666.1 EPY50435.1 - 0.1 11.5 0.0 0.28 10.1 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Na_H_Exchanger PF00999.16 EPY50436.1 - 3.2e-64 216.8 30.2 3.7e-64 216.6 20.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peptidase_M56 PF05569.6 EPY50436.1 - 0.61 8.9 3.2 6.3 5.6 0.1 2.6 3 0 0 3 3 3 0 BlaR1 peptidase M56 ApbA PF02558.11 EPY50437.1 - 4.2e-33 113.9 0.1 6.1e-33 113.4 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPY50437.1 - 1.6e-27 96.0 0.1 2.6e-27 95.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 EPY50437.1 - 0.00078 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EPY50437.1 - 0.025 14.5 0.0 0.091 12.7 0.0 2.0 1 1 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EPY50437.1 - 0.05 14.0 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EPY50437.1 - 0.11 11.3 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase MFS_1 PF07690.11 EPY50438.1 - 9.2e-32 110.1 35.3 9.2e-32 110.1 24.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY50438.1 - 0.013 14.0 35.1 0.066 11.7 24.3 2.0 1 1 0 1 1 1 0 Sugar (and other) transporter Fungal_trans PF04082.13 EPY50439.1 - 8.4e-38 129.7 0.0 1.5e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY50439.1 - 1.1e-08 34.8 13.6 2e-08 33.9 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EPY50440.1 - 3.3e-33 112.3 8.4 3.9e-09 36.0 0.1 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPY50440.1 - 0.0053 16.5 0.6 9.7 6.0 0.0 4.5 4 2 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Fmp27_WPPW PF10359.4 EPY50441.1 - 1.1e-123 413.2 9.5 3e-123 411.7 6.6 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 EPY50441.1 - 1.4e-120 403.3 1.3 1.4e-120 403.3 0.9 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.4 EPY50441.1 - 4.4e-73 246.4 32.7 4.4e-73 246.4 22.7 1.9 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.4 EPY50441.1 - 7.6e-49 165.6 0.1 1.6e-48 164.5 0.1 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EPY50441.1 - 3.8e-42 143.6 0.2 1.1e-41 142.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EPY50441.1 - 5e-23 81.4 0.0 6.8e-22 77.8 0.0 3.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.8 EPY50441.1 - 0.00053 19.6 0.2 0.0014 18.3 0.2 1.7 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Ribosomal_L32e PF01655.13 EPY50442.1 - 9.4e-49 164.0 1.3 1.1e-48 163.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 NAD_kinase PF01513.16 EPY50443.1 - 1.7e-70 237.0 0.0 2.7e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF4598 PF15370.1 EPY50444.1 - 1.3e-10 41.5 4.1 1.3e-10 41.5 2.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4598) DUF972 PF06156.8 EPY50444.1 - 0.82 10.0 6.0 0.31 11.4 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_L18p PF00861.17 EPY50445.1 - 2.5e-43 147.0 0.2 8.3e-43 145.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EPY50445.1 - 6.6e-30 103.5 3.9 6.6e-30 103.5 2.7 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EPY50445.1 - 0.065 13.2 0.1 0.27 11.2 0.1 2.0 1 1 0 1 1 1 0 Threonine synthase N terminus TruB_N PF01509.13 EPY50446.1 - 1.6e-41 141.9 0.0 1.4e-39 135.6 0.0 2.2 2 0 0 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) DUF2201_N PF13203.1 EPY50446.1 - 0.35 9.9 5.0 0.52 9.4 3.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain ResIII PF04851.10 EPY50447.1 - 3.9e-23 82.2 0.0 3.8e-22 78.9 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPY50447.1 - 1e-13 50.9 0.0 4.8e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY50447.1 - 3e-13 49.6 0.0 5.3e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPY50447.1 - 0.00099 19.2 0.0 0.0064 16.6 0.0 2.3 2 2 0 2 2 2 1 AAA domain cobW PF02492.14 EPY50447.1 - 0.0021 17.5 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Flavi_DEAD PF07652.9 EPY50447.1 - 0.0032 17.2 0.1 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_14 PF13173.1 EPY50447.1 - 0.02 14.8 0.0 0.11 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 EPY50447.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 Helicase C-terminal domain Rrn6 PF10214.4 EPY50448.1 - 1.8e-66 224.7 14.6 8.1e-66 222.6 10.2 1.9 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor NIF PF03031.13 EPY50449.1 - 6e-49 165.7 0.3 9.5e-49 165.1 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sas10 PF09368.5 EPY50450.1 - 5.7e-27 93.7 5.1 5.7e-27 93.7 3.6 2.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EPY50450.1 - 2.8e-12 46.6 0.0 1e-11 44.8 0.0 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Auto_anti-p27 PF06677.7 EPY50451.1 - 7.2e-16 57.6 2.3 1e-15 57.1 1.6 1.2 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF913 PF06025.7 EPY50451.1 - 0.047 12.4 0.1 0.052 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2387 PF09526.5 EPY50451.1 - 4.4 7.3 8.5 0.51 10.2 2.0 2.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) FA_desaturase PF00487.19 EPY50452.1 - 6.3e-26 91.3 19.4 8.9e-26 90.8 13.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EPY50452.1 - 6.4e-17 60.5 0.4 1.1e-16 59.7 0.3 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Ytp1 PF10355.4 EPY50453.1 - 1e-102 343.0 10.5 1e-102 343.0 7.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EPY50453.1 - 4e-26 90.6 10.5 4e-26 90.6 7.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) VIT1 PF01988.14 EPY50453.1 - 2.1 7.7 8.1 0.61 9.5 0.4 2.8 2 1 0 2 2 2 0 VIT family Diphthamide_syn PF01866.12 EPY50454.1 - 5e-113 377.3 0.0 6.1e-113 377.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribonuc_L-PSP PF01042.16 EPY50454.1 - 0.0062 16.2 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Endoribonuclease L-PSP SPX PF03105.14 EPY50455.1 - 6.1e-42 144.2 10.0 2.3e-41 142.3 6.9 1.9 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EPY50455.1 - 1.7e-28 99.7 36.3 2.1e-28 99.4 25.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EPY50455.1 - 2.1e-14 52.8 15.2 2.1e-14 52.8 10.5 2.4 1 1 1 2 2 2 2 Citrate transporter CENP-B_dimeris PF09026.5 EPY50455.1 - 0.0036 17.4 3.3 0.0092 16.2 2.3 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EPY50455.1 - 0.28 10.7 3.0 0.5 9.9 2.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EPY50455.1 - 0.71 9.3 6.6 1.1 8.7 4.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EPY50455.1 - 0.83 9.8 5.4 1.9 8.6 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Saccharop_dh PF03435.13 EPY50457.1 - 7.5e-127 423.4 0.0 9.3e-127 423.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EPY50457.1 - 0.00013 22.1 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EPY50457.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF2100 PF09873.4 EPY50457.1 - 0.022 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) GFO_IDH_MocA PF01408.17 EPY50457.1 - 0.027 14.9 0.0 0.23 11.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EPY50457.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EPY50457.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CBFD_NFYB_HMF PF00808.18 EPY50458.1 - 1.4e-16 60.2 0.3 2.2e-16 59.6 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPY50458.1 - 2.5e-10 40.3 0.2 3.8e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EPY50458.1 - 0.039 13.7 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pyr_redox_2 PF07992.9 EPY50459.1 - 1.4e-06 28.3 0.0 2e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPY50459.1 - 0.0041 17.1 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPY50459.1 - 0.0056 16.4 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPY50459.1 - 0.14 10.9 0.0 0.62 8.9 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein RRM_1 PF00076.17 EPY50460.1 - 4.8e-16 58.1 0.0 6.6e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50460.1 - 3.2e-10 39.7 0.0 7.6e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50460.1 - 3.7e-10 39.6 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.4 EPY50461.1 - 1.5e-12 46.2 5.3 2.2e-10 39.0 1.6 3.1 3 0 0 3 3 3 3 Nuclear pore component DUF2346 PF09803.4 EPY50461.1 - 0.093 12.5 1.3 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) CTP_transf_1 PF01148.15 EPY50462.1 - 5.4e-86 288.4 27.6 6.6e-86 288.1 19.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family AA_permease_C PF13906.1 EPY50462.1 - 3.9 7.4 12.7 2.2 8.2 0.2 3.7 3 1 0 3 3 3 0 C-terminus of AA_permease PTR2 PF00854.16 EPY50463.1 - 4.4e-59 200.1 15.4 4.4e-59 200.1 10.7 2.0 1 1 1 2 2 2 2 POT family Fumble PF03630.9 EPY50464.1 - 5.3e-141 469.3 1.8 6.3e-141 469.1 1.2 1.0 1 0 0 1 1 1 1 Fumble NCA2 PF08637.5 EPY50465.1 - 6.9e-86 287.7 8.2 1.2e-85 286.9 5.7 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Bromodomain PF00439.20 EPY50466.1 - 2.2e-26 91.5 4.0 3.6e-21 74.8 0.2 2.8 3 0 0 3 3 3 2 Bromodomain BAH PF01426.13 EPY50466.1 - 2.3e-20 72.4 0.0 5.4e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 BAH domain eIF2A PF08662.6 EPY50467.1 - 1.2e-78 263.2 0.0 7.7e-78 260.6 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EPY50467.1 - 0.014 15.2 1.4 0.6 10.0 0.1 3.8 4 1 0 4 4 4 0 WD domain, G-beta repeat CDV3 PF15359.1 EPY50467.1 - 0.02 14.9 0.4 0.094 12.7 0.2 2.2 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF1656 PF07869.7 EPY50467.1 - 0.22 11.3 0.0 0.49 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) LSM PF01423.17 EPY50468.1 - 1.5e-19 69.2 0.3 1.7e-19 69.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain RRM_1 PF00076.17 EPY50469.1 - 1.1e-23 82.6 0.0 8.7e-11 41.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50469.1 - 3.2e-18 65.3 0.0 6.1e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50469.1 - 5e-18 64.8 0.0 1.6e-08 34.3 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPY50469.1 - 0.018 14.7 0.0 0.046 13.4 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 ESCRT-II PF05871.7 EPY50470.1 - 1.4e-41 141.6 6.5 8.6e-41 139.1 3.8 1.9 1 1 1 2 2 2 1 ESCRT-II complex subunit TrmB PF01978.14 EPY50470.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sugar_tr PF00083.19 EPY50471.1 - 3e-117 391.9 24.7 3.5e-117 391.7 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY50471.1 - 6.8e-16 57.9 30.7 1.2e-12 47.1 13.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2763 PF10961.3 EPY50471.1 - 0.023 15.0 0.1 0.023 15.0 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2763) Pox_A14 PF05767.7 EPY50471.1 - 0.19 11.7 4.3 0.31 11.0 0.1 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 MFS_3 PF05977.8 EPY50471.1 - 1 7.3 12.2 0.091 10.8 5.2 1.5 2 0 0 2 2 2 0 Transmembrane secretion effector TPR_14 PF13428.1 EPY50472.1 - 6.6e-08 32.5 0.0 0.083 13.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPY50472.1 - 0.0011 19.5 0.0 0.025 15.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 EPY50472.1 - 0.0016 18.2 0.6 0.2 11.3 0.1 2.5 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 EPY50472.1 - 0.0031 16.4 1.5 0.12 11.2 0.0 3.4 3 1 1 4 4 4 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.1 EPY50472.1 - 0.16 12.3 0.0 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat APG5 PF04106.7 EPY50473.1 - 2.6e-49 167.3 0.0 4e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1833 PF08875.6 EPY50474.1 - 0.045 12.9 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) IGR PF09597.5 EPY50475.1 - 9.5e-19 67.0 1.1 1.4e-18 66.5 0.8 1.3 1 0 0 1 1 1 1 IGR protein motif DUF3650 PF12368.3 EPY50475.1 - 0.029 13.8 0.4 0.049 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) MFS_1 PF07690.11 EPY50476.1 - 5.5e-38 130.5 20.9 8.8e-38 129.9 14.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Syja_N PF02383.13 EPY50477.1 - 1.3e-87 293.5 0.1 2.6e-87 292.5 0.1 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EPY50477.1 - 3.8e-28 99.0 0.1 1.5e-27 97.1 0.1 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Sec61_beta PF03911.11 EPY50478.1 - 1e-18 66.7 0.9 1.3e-18 66.4 0.6 1.1 1 0 0 1 1 1 1 Sec61beta family Ribonuc_L-PSP PF01042.16 EPY50479.1 - 9.6e-41 138.3 0.0 1.2e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Adaptin_N PF01602.15 EPY50480.1 - 7.6e-121 404.0 9.3 8.9e-121 403.7 6.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPY50480.1 - 4.3e-12 46.1 0.1 3.5e-05 24.0 0.0 4.8 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 EPY50480.1 - 4.8e-07 29.3 0.0 0.6 10.3 0.0 4.7 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.2 EPY50480.1 - 6.7e-07 29.3 4.7 6.8e-07 29.2 0.2 3.0 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 EPY50480.1 - 0.0012 18.0 0.2 0.012 14.7 0.1 2.3 2 0 0 2 2 2 1 Armadillo-like HEAT_EZ PF13513.1 EPY50480.1 - 0.0023 18.3 0.6 59 4.3 0.0 5.4 5 1 1 6 6 6 0 HEAT-like repeat MOR2-PAG1_C PF14225.1 EPY50480.1 - 0.025 14.3 0.1 1.9 8.2 0.0 3.1 2 1 2 4 4 4 0 Cell morphogenesis C-terminal Ribosomal_L13 PF00572.13 EPY50481.1 - 1.6e-26 92.8 0.0 3.5e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 Mit_ribos_Mrp51 PF11709.3 EPY50482.1 - 6.2e-26 91.3 0.3 5.4e-25 88.2 0.1 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit FTHFS PF01268.14 EPY50483.1 - 8.7e-254 842.6 0.7 1.1e-253 842.2 0.5 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EPY50483.1 - 6.1e-68 226.9 2.3 6.1e-68 226.9 1.6 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EPY50483.1 - 1.4e-40 137.9 0.8 4.6e-40 136.3 0.5 2.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain PhnA PF03831.9 EPY50483.1 - 0.09 12.2 0.2 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 PhnA protein Cyclin_N PF00134.18 EPY50484.1 - 1.9e-08 33.9 0.3 3.1e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1074 PF06382.6 EPY50484.1 - 0.0062 16.5 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1074) XK-related PF09815.4 EPY50485.1 - 0.0012 17.8 0.1 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 XK-related protein DUF2919 PF11143.3 EPY50485.1 - 0.02 14.7 0.2 0.028 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) NMT_C PF02799.10 EPY50486.1 - 1.1e-74 250.0 0.0 8e-74 247.1 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EPY50486.1 - 6.5e-74 246.9 0.1 9.6e-74 246.3 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_7 PF13508.1 EPY50486.1 - 0.022 14.8 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_His PF13393.1 EPY50487.1 - 1.1e-40 139.6 0.0 3.8e-35 121.4 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EPY50487.1 - 2.7e-17 62.8 0.0 5.8e-17 61.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.15 EPY50487.1 - 1.5e-15 56.6 1.4 3.9e-15 55.2 1.0 1.8 1 0 0 1 1 1 1 WHEP-TRS domain HGTP_anticodon PF03129.15 EPY50487.1 - 3.8e-13 49.2 0.0 9.4e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EPY50487.1 - 0.0045 15.8 0.1 0.85 8.3 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EPY50487.1 - 0.031 13.4 0.1 0.076 12.1 0.0 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs ORF6C PF10552.4 EPY50487.1 - 0.1 12.3 0.1 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 ORF6C domain dCMP_cyt_deam_1 PF00383.17 EPY50488.1 - 1.5e-25 88.7 2.1 2.2e-25 88.2 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EPY50488.1 - 8.7e-05 23.3 0.0 0.0002 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY50488.1 - 0.0016 18.7 0.1 0.0061 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain XOO_2897-deam PF14440.1 EPY50488.1 - 0.018 14.7 0.2 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase AAA_33 PF13671.1 EPY50488.1 - 0.038 13.8 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cys_rich_CWC PF14375.1 EPY50488.1 - 0.052 13.4 11.0 0.1 12.5 7.7 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC KTI12 PF08433.5 EPY50488.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sugarporin_N PF11471.3 EPY50489.1 - 0.028 14.0 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension FtsJ PF01728.14 EPY50490.1 - 9.1e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EPY50490.1 - 0.0003 20.5 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY50490.1 - 0.0075 16.8 0.0 0.016 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPY50490.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EPY50491.1 - 2.7e-56 190.4 0.0 3.1e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EPY50491.1 - 2.9e-07 30.3 0.0 4.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY50491.1 - 0.00044 20.7 0.0 0.00092 19.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY50491.1 - 0.017 14.7 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 EPY50491.1 - 0.071 12.6 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) His_biosynth PF00977.16 EPY50492.1 - 2.4e-44 151.3 0.2 1.1e-43 149.1 0.2 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EPY50492.1 - 2.4e-27 95.6 0.0 4.5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EPY50492.1 - 2.2e-06 27.4 0.0 1.3e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPY50492.1 - 5.5e-06 26.0 0.0 9.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Rft-1 PF04506.8 EPY50493.1 - 6.9e-131 437.2 29.4 8.6e-131 436.9 20.4 1.0 1 0 0 1 1 1 1 Rft protein SPC12 PF06645.8 EPY50493.1 - 2.1 8.2 5.9 3.4 7.5 0.2 3.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) SAGA-Tad1 PF12767.2 EPY50494.1 - 3.7e-44 151.3 0.2 4.8e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Uteroglobin PF01099.12 EPY50494.1 - 0.00023 20.8 0.3 0.64 9.8 0.2 3.2 3 0 0 3 3 3 2 Uteroglobin family Xan_ur_permease PF00860.15 EPY50495.1 - 4.5e-26 91.2 33.8 1.4e-25 89.6 21.5 2.5 2 1 0 2 2 2 1 Permease family DUF3278 PF11683.3 EPY50495.1 - 0.26 11.2 0.0 0.26 11.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) FA_hydroxylase PF04116.8 EPY50496.1 - 7.7e-19 68.1 11.4 7.7e-19 68.1 7.9 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PIF1 PF05970.9 EPY50497.1 - 1.2e-62 211.9 2.3 1.5e-48 165.6 0.1 2.5 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EPY50497.1 - 7.4e-19 68.1 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPY50497.1 - 1.7e-07 31.4 0.1 5.7e-07 29.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Herpes_Helicase PF02689.9 EPY50497.1 - 2.7e-06 25.4 0.3 5.6e-05 21.1 0.0 2.2 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 EPY50497.1 - 5.2e-06 26.1 0.2 1.1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EPY50497.1 - 1.5e-05 25.0 0.1 0.00017 21.6 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 EPY50497.1 - 4.5e-05 23.1 0.8 0.011 15.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 EPY50497.1 - 8.4e-05 21.7 0.1 0.0035 16.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EPY50497.1 - 0.00012 21.3 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EPY50497.1 - 0.0003 19.7 0.1 0.00061 18.7 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EPY50497.1 - 0.00078 19.4 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EPY50497.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.11 EPY50497.1 - 0.0019 17.4 0.3 0.0053 16.0 0.1 1.8 2 1 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.13 EPY50497.1 - 0.0028 17.1 0.7 3.7 6.9 0.4 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EPY50497.1 - 0.0044 16.7 0.5 0.029 14.0 0.3 2.1 1 1 0 1 1 1 1 Archaeal ATPase Sigma54_activat PF00158.21 EPY50497.1 - 0.0045 16.4 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 EPY50497.1 - 0.005 15.5 0.6 0.0096 14.5 0.1 1.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 EPY50497.1 - 0.0068 16.6 0.1 0.018 15.2 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPY50497.1 - 0.011 15.4 1.0 0.057 13.1 0.7 2.1 1 1 0 1 1 1 0 NTPase Helicase_RecD PF05127.9 EPY50497.1 - 0.012 15.2 1.9 0.057 13.0 1.3 2.0 1 1 0 1 1 1 0 Helicase AAA_14 PF13173.1 EPY50497.1 - 0.012 15.4 0.4 0.061 13.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPY50497.1 - 0.013 15.6 0.1 0.06 13.5 0.1 2.2 1 1 0 1 1 1 0 RNA helicase MobB PF03205.9 EPY50497.1 - 0.013 15.2 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EPY50497.1 - 0.024 14.0 0.1 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 EPY50497.1 - 0.043 13.5 1.2 0.26 11.0 0.3 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EPY50497.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 DUF258 PF03193.11 EPY50497.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UvrD-helicase PF00580.16 EPY50497.1 - 0.066 12.4 0.9 0.13 11.4 0.1 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ABC_tran PF00005.22 EPY50497.1 - 0.087 13.1 0.2 0.3 11.3 0.0 2.2 2 1 0 2 2 1 0 ABC transporter cobW PF02492.14 EPY50497.1 - 0.11 11.9 1.0 0.15 11.4 0.0 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain HAD PF12710.2 EPY50498.1 - 1.5e-19 70.8 0.3 3.8e-19 69.5 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY50498.1 - 3e-14 53.9 0.2 4.1e-13 50.2 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPY50498.1 - 6.4e-14 51.5 0.0 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EPY50498.1 - 8.4e-11 41.6 0.0 2.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPY50498.1 - 0.0036 16.9 0.6 0.01 15.4 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ketoacyl-synt PF00109.21 EPY50499.1 - 1.8e-55 188.2 0.2 6.3e-55 186.3 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPY50499.1 - 3.2e-35 120.5 0.1 6e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EPY50499.1 - 4.7e-07 29.0 0.1 3.4e-06 26.2 0.1 2.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EPY50499.1 - 0.00082 18.9 0.5 1.1 9.0 0.3 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PseudoU_synth_1 PF01416.15 EPY50500.1 - 4.9e-20 71.9 0.0 1.3e-10 41.6 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 EPY50500.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Response_reg PF00072.19 EPY50501.1 - 5.2e-23 81.1 0.1 7.8e-16 58.0 0.1 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Dicty_REP PF05086.7 EPY50501.1 - 0.059 11.1 2.1 0.083 10.6 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_S19e PF01090.14 EPY50502.1 - 5.6e-60 200.8 0.1 6.3e-60 200.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Kinesin PF00225.18 EPY50503.1 - 2.6e-111 371.5 0.0 3.6e-111 371.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Surf_Ag_VNR PF07244.10 EPY50503.1 - 0.012 16.0 0.1 0.066 13.6 0.0 2.3 2 0 0 2 2 2 0 Surface antigen variable number repeat VID27 PF08553.5 EPY50504.1 - 2.3e-274 912.5 14.6 2.8e-274 912.2 10.1 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein MARVEL PF01284.18 EPY50505.1 - 2.1e-18 66.5 13.2 2.6e-18 66.2 9.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain FtsH_ext PF06480.10 EPY50505.1 - 0.39 10.9 1.8 0.89 9.7 0.3 2.0 2 0 0 2 2 2 0 FtsH Extracellular Yip1 PF04893.12 EPY50505.1 - 3.5 7.1 13.4 2.7 7.4 0.6 2.2 1 1 0 2 2 2 0 Yip1 domain AAA_17 PF13207.1 EPY50506.1 - 0.057 14.2 0.1 0.73 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPY50506.1 - 0.64 10.3 0.0 0.64 10.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain Ribosomal_S27e PF01667.12 EPY50507.1 - 5e-29 99.6 5.2 6.7e-29 99.2 3.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EPY50507.1 - 0.0086 15.9 1.3 0.01 15.7 0.9 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EPY50507.1 - 0.082 12.2 2.5 0.12 11.7 1.7 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Ribosomal_S14 PF00253.16 EPY50508.1 - 1.1e-17 63.1 1.6 1.2e-17 63.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Terpene_synth PF01397.16 EPY50508.1 - 0.029 13.7 0.0 0.029 13.7 0.0 1.0 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain PHD PF00628.24 EPY50509.1 - 6.3e-09 35.3 7.5 1.4e-08 34.2 5.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPY50509.1 - 0.0044 16.3 7.3 0.0083 15.4 5.1 1.4 1 0 0 1 1 1 1 PHD-finger Aa_trans PF01490.13 EPY50510.1 - 4.6e-80 269.0 36.4 5.6e-80 268.8 25.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAP_assoc PF03828.14 EPY50511.1 - 1.4e-17 63.3 0.4 3.7e-17 62.0 0.1 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPY50511.1 - 0.00058 20.1 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PDZ_1 PF12812.2 EPY50512.1 - 6.3e-33 112.4 0.0 3.7e-26 90.8 0.0 3.0 3 0 0 3 3 3 2 PDZ-like domain PDZ PF00595.19 EPY50512.1 - 1.6e-11 44.1 0.0 0.0066 16.5 0.0 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 EPY50512.1 - 1.3e-09 38.0 0.0 5.9e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EPY50512.1 - 2.8e-08 33.5 0.0 0.087 12.7 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Peptidase_S46 PF10459.4 EPY50512.1 - 0.12 10.8 1.4 0.84 7.9 0.2 2.0 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S3 PF00944.14 EPY50512.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Alphavirus core protein Peptidase_S7 PF00949.16 EPY50512.1 - 0.99 8.8 3.1 2.2 7.6 2.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease AAA_27 PF13514.1 EPY50513.1 - 0.0015 16.3 4.4 0.0018 16.0 3.0 1.1 1 0 0 1 1 1 1 AAA domain Fib_alpha PF08702.5 EPY50513.1 - 0.0037 17.4 4.9 0.015 15.4 0.4 3.2 3 0 0 3 3 3 1 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EPY50513.1 - 0.036 11.9 6.5 0.052 11.4 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1798 PF08807.5 EPY50513.1 - 0.044 13.4 1.4 0.1 12.3 0.3 2.2 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Gp58 PF07902.6 EPY50513.1 - 0.085 11.0 1.1 0.11 10.6 0.8 1.2 1 0 0 1 1 1 0 gp58-like protein DUF848 PF05852.6 EPY50513.1 - 0.12 12.2 8.5 0.19 11.6 4.8 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.10 EPY50513.1 - 0.18 11.3 6.0 0.32 10.5 0.2 3.4 1 1 2 3 3 3 0 Septum formation initiator DUF2130 PF09903.4 EPY50513.1 - 0.24 10.0 8.4 0.51 9.0 5.2 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) CENP-F_leu_zip PF10473.4 EPY50513.1 - 0.28 11.0 13.1 0.42 10.4 7.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EPY50513.1 - 0.33 9.9 12.5 0.57 9.1 8.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 EPY50513.1 - 0.46 10.2 12.1 0.13 12.1 4.9 2.2 1 1 0 2 2 2 0 Axonemal dynein light chain DUF349 PF03993.7 EPY50513.1 - 0.76 9.9 5.0 40 4.4 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) IATP PF04568.7 EPY50513.1 - 1 9.4 5.5 4.7 7.2 3.8 2.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Pox_A_type_inc PF04508.7 EPY50513.1 - 1.3 8.9 5.3 1.1 9.2 0.1 3.2 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat ZapA PF05164.8 EPY50513.1 - 1.5 8.8 5.2 0.83 9.6 1.0 2.4 1 1 1 2 2 2 0 Cell division protein ZapA Allexi_40kDa PF05549.6 EPY50513.1 - 1.9 7.7 7.7 4.1 6.6 2.1 2.7 1 1 3 4 4 4 0 Allexivirus 40kDa protein DUF4200 PF13863.1 EPY50513.1 - 1.9 8.4 14.6 1.4 8.8 7.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 EPY50513.1 - 2.2 8.1 15.6 0.087 12.6 2.5 3.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 EPY50513.1 - 3.5 5.9 8.8 3.5 5.9 4.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 EPY50513.1 - 5.8 6.6 17.1 0.88 9.3 8.1 2.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Selenoprotein_S PF06936.6 EPY50513.1 - 5.8 6.4 6.9 2.7 7.4 2.9 1.9 1 1 1 2 2 2 0 Selenoprotein S (SelS) XhlA PF10779.4 EPY50513.1 - 6.4 6.7 8.5 60 3.6 5.0 2.9 1 1 1 2 2 2 0 Haemolysin XhlA ATG16 PF08614.6 EPY50513.1 - 9.4 6.0 15.3 57 3.4 10.6 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ATP_synt_H PF05493.8 EPY50514.1 - 2.9e-21 75.2 3.5 3.1e-21 75.2 2.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 EPY50514.1 - 0.0094 15.3 2.2 0.01 15.2 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) UPF0104 PF03706.8 EPY50514.1 - 0.016 14.5 0.5 0.017 14.3 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Frag1 PF10277.4 EPY50514.1 - 0.05 13.0 2.1 0.053 12.9 1.4 1.0 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4199 PF13858.1 EPY50514.1 - 0.058 13.3 2.7 0.067 13.1 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Cation_ATPase_C PF00689.16 EPY50514.1 - 0.072 12.6 0.7 0.078 12.5 0.5 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus MFS_Mycoplasma PF07672.8 EPY50514.1 - 0.079 12.1 0.2 0.083 12.0 0.1 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter YibE_F PF07907.6 EPY50514.1 - 0.098 11.8 0.6 0.11 11.6 0.4 1.0 1 0 0 1 1 1 0 YibE/F-like protein 7tm_3 PF00003.17 EPY50514.1 - 0.12 11.7 5.4 0.14 11.5 3.7 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Hum_adeno_E3A PF05393.6 EPY50514.1 - 0.12 12.0 0.4 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF2207 PF09972.4 EPY50514.1 - 0.18 10.3 0.8 0.17 10.4 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 EPY50514.1 - 0.25 9.9 3.2 0.28 9.8 2.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily SdpI PF13630.1 EPY50514.1 - 0.74 9.5 3.9 0.85 9.3 2.7 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family ABC2_membrane_4 PF12730.2 EPY50514.1 - 0.77 8.8 5.3 0.85 8.7 3.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ARL6IP6 PF15062.1 EPY50514.1 - 1.4 8.9 3.9 0.51 10.2 0.2 1.8 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix ABC_membrane PF00664.18 EPY50514.1 - 5 6.4 5.8 37 3.5 4.0 1.8 1 1 0 1 1 1 0 ABC transporter transmembrane region Peptidase_S24 PF00717.18 EPY50515.1 - 6.4e-08 32.1 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Ribosomal_L7Ae PF01248.21 EPY50516.1 - 1.5e-28 98.1 1.0 2e-28 97.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RuvA_C PF07499.8 EPY50516.1 - 0.35 11.0 1.9 0.63 10.2 0.3 2.2 2 0 0 2 2 2 0 RuvA, C-terminal domain DSPc PF00782.15 EPY50517.1 - 5e-34 116.7 0.2 7.2e-34 116.2 0.2 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPY50517.1 - 0.0017 17.7 1.1 0.014 14.7 0.1 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EPY50517.1 - 0.066 12.0 0.2 0.081 11.7 0.2 1.3 1 1 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Dpy-30 PF05186.8 EPY50519.1 - 3e-17 61.8 0.0 4.1e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Radial_spoke PF04712.7 EPY50519.1 - 0.015 14.1 0.8 0.016 13.9 0.6 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF533 PF04391.7 EPY50519.1 - 0.1 11.9 0.2 0.15 11.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Dak2 PF02734.12 EPY50519.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 DAK2 domain vMSA PF00695.14 EPY50519.1 - 0.26 10.4 2.0 0.31 10.1 1.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Iso_dh PF00180.15 EPY50520.1 - 1.2e-96 323.6 0.0 1.4e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 EPY50520.1 - 0.035 13.9 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif RRM_6 PF14259.1 EPY50521.1 - 2.7e-10 40.0 0.0 6.6e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY50521.1 - 1e-07 31.4 2.2 7.3e-06 25.5 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50521.1 - 0.00033 20.4 0.2 0.0017 18.1 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1330 PF07045.6 EPY50521.1 - 0.0087 15.8 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1330) DUF1886 PF09171.5 EPY50521.1 - 0.096 11.6 3.1 0.17 10.8 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) SHIPPO-rpt PF07004.7 EPY50521.1 - 0.17 12.8 1.5 8.6 7.4 0.1 3.1 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat RRM_3 PF08777.6 EPY50521.1 - 9.4 6.1 9.7 3.3 7.6 0.0 3.3 3 1 1 4 4 4 0 RNA binding motif Spo7 PF03907.8 EPY50522.1 - 5.6e-24 84.9 8.9 4.4e-08 32.9 0.5 3.1 1 1 2 3 3 3 3 Spo7-like protein CytochromB561_N PF09786.4 EPY50522.1 - 0.011 14.2 5.0 0.012 14.1 3.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal AAA PF00004.24 EPY50523.1 - 2e-08 34.5 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY50523.1 - 6e-07 29.6 0.1 1.1e-05 25.5 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPY50523.1 - 4.9e-06 26.4 0.1 2e-05 24.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EPY50523.1 - 9.7e-06 25.2 0.1 2.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPY50523.1 - 2.1e-05 25.3 0.0 7.1e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPY50523.1 - 2.2e-05 24.2 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EPY50523.1 - 7.6e-05 21.5 1.0 0.16 10.6 0.0 3.2 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EPY50523.1 - 0.00013 22.0 0.1 0.00057 19.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EPY50523.1 - 0.00059 18.9 0.1 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EPY50523.1 - 0.00066 19.3 0.1 0.0019 17.8 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 EPY50523.1 - 0.0011 19.2 0.0 0.0045 17.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 EPY50523.1 - 0.003 16.7 0.1 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EPY50523.1 - 0.0041 17.0 0.0 0.0099 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPY50523.1 - 0.0053 16.3 0.3 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPY50523.1 - 0.0059 16.9 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 EPY50523.1 - 0.0083 15.2 0.0 0.049 12.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EPY50523.1 - 0.011 14.6 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DNA_pol3_delta PF06144.8 EPY50523.1 - 0.022 14.2 0.0 0.055 12.9 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.17 EPY50523.1 - 0.023 14.8 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EPY50523.1 - 0.04 13.0 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 EPY50523.1 - 0.044 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 EPY50523.1 - 0.047 12.9 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NTPase_1 PF03266.10 EPY50523.1 - 0.067 12.9 0.2 0.17 11.5 0.1 1.7 1 1 0 1 1 1 0 NTPase T2SE PF00437.15 EPY50523.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 EPY50523.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EPY50523.1 - 0.17 11.2 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Spc97_Spc98 PF04130.8 EPY50524.1 - 7.1e-98 328.2 21.8 1.1e-97 327.6 15.1 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family UTP15_C PF09384.5 EPY50525.1 - 9.3e-46 155.1 0.0 1.8e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EPY50525.1 - 4.7e-26 89.6 5.3 1.2e-07 31.2 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat CDT1 PF08839.6 EPY50526.1 - 4.5e-07 29.9 2.6 1.5e-06 28.2 0.3 2.6 2 1 0 2 2 2 1 DNA replication factor CDT1 like Avirulence PF03377.8 EPY50526.1 - 0.09 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA CYSTM PF12734.2 EPY50527.1 - 1.5e-07 31.3 38.9 7.8e-05 22.6 26.9 3.2 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance Cut12 PF11500.3 EPY50528.1 - 1.6e-20 73.2 0.3 7.6e-20 71.1 0.2 2.2 1 0 0 1 1 1 1 Spindle pole body formation-associated protein SecY PF00344.15 EPY50529.1 - 7.3e-90 301.3 15.0 9.3e-90 301.0 10.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EPY50529.1 - 9.2e-17 60.2 0.2 9.2e-17 60.2 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p RseC_MucC PF04246.7 EPY50529.1 - 0.22 11.0 0.1 0.22 11.0 0.0 2.4 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC MMR_HSR1 PF01926.18 EPY50530.1 - 5.8e-21 74.6 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EPY50530.1 - 8.2e-21 73.6 0.0 1.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EPY50530.1 - 1e-12 47.6 0.0 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPY50530.1 - 4.2e-05 23.4 0.2 0.041 13.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EPY50530.1 - 0.0021 18.5 0.0 0.01 16.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 EPY50530.1 - 0.03 14.2 0.1 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPY50530.1 - 0.087 11.5 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_29 PF13555.1 EPY50530.1 - 0.093 12.2 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPY50530.1 - 0.13 12.6 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.27 EPY50531.1 - 3e-54 179.0 20.2 1.3e-11 43.9 0.4 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EPY50531.1 - 2.8e-07 29.0 8.0 0.39 8.7 0.0 5.3 2 1 3 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY50531.1 - 0.00011 21.1 7.3 0.022 13.4 0.1 3.8 1 1 2 4 4 4 2 Nup133 N terminal like eIF2A PF08662.6 EPY50531.1 - 0.00023 20.9 0.3 0.43 10.2 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EPY50531.1 - 0.0024 16.7 0.1 0.29 9.8 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Nbas_N PF15492.1 EPY50531.1 - 0.033 13.2 0.3 3.3 6.7 0.0 3.1 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal HLH PF00010.21 EPY50533.1 - 1.1e-16 60.3 0.6 2e-16 59.3 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SF-assemblin PF06705.6 EPY50533.1 - 0.019 14.1 1.6 0.029 13.5 1.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin UPF0182 PF03699.8 EPY50533.1 - 0.092 10.6 0.2 0.13 10.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) HALZ PF02183.13 EPY50533.1 - 0.21 11.2 0.8 0.52 10.0 0.5 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Ribosomal_S16 PF00886.14 EPY50534.1 - 5.3e-24 83.7 0.1 6.4e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Oxysterol_BP PF01237.13 EPY50535.1 - 6.6e-79 264.9 0.1 1e-78 264.3 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein DUF221 PF02714.10 EPY50536.1 - 2.4e-76 256.6 23.1 2.4e-76 256.6 16.0 2.6 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPY50536.1 - 6e-32 110.3 9.1 6e-32 110.3 6.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPY50536.1 - 9.3e-14 51.7 0.8 1.7e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) TFR_dimer PF04253.10 EPY50537.1 - 7.7e-24 83.6 0.0 1.8e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EPY50537.1 - 3.1e-08 33.5 0.0 6.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPY50537.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 PA domain DUF4396 PF14342.1 EPY50538.1 - 0.037 14.1 5.6 0.053 13.6 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4396) Adipogenin PF15202.1 EPY50538.1 - 2.2 8.2 6.0 6 6.8 4.2 1.8 1 0 0 1 1 1 0 Adipogenin DUF373 PF04123.8 EPY50539.1 - 0.12 11.3 2.3 0.17 10.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2208 PF09973.4 EPY50539.1 - 0.21 10.8 3.4 6.6 5.8 1.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF999 PF06198.6 EPY50539.1 - 0.59 9.9 6.1 0.58 9.9 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF999) HlyIII PF03006.15 EPY50539.1 - 0.99 8.7 11.9 0.62 9.4 0.1 2.2 1 1 1 2 2 2 0 Haemolysin-III related TMEM171 PF15471.1 EPY50539.1 - 7.3 5.2 7.4 1.3 7.7 2.3 1.8 1 1 1 2 2 2 0 Transmembrane protein family 171 RTA1 PF04479.8 EPY50540.1 - 0.0097 15.4 1.4 0.013 14.9 0.9 1.1 1 0 0 1 1 1 1 RTA1 like protein CUE PF02845.11 EPY50541.1 - 3.6e-07 29.5 0.0 6.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain Gp_dh_C PF02800.15 EPY50542.1 - 2.4e-73 244.7 0.0 3.6e-73 244.2 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPY50542.1 - 1.7e-60 203.3 0.2 2.6e-60 202.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EPY50542.1 - 0.021 14.3 0.1 0.066 12.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DapB_N PF01113.15 EPY50542.1 - 0.036 13.9 0.5 0.14 12.1 0.3 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EPY50542.1 - 0.088 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RhoGAP PF00620.22 EPY50543.1 - 1.4e-16 60.4 0.0 5e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain MRP-63 PF14978.1 EPY50543.1 - 0.58 10.6 4.6 0.19 12.1 0.9 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Arm PF00514.18 EPY50544.1 - 8.5e-72 234.7 28.9 9.3e-09 34.7 0.3 11.8 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPY50544.1 - 1.7e-20 73.0 14.9 0.00095 19.4 2.6 7.9 1 1 5 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EPY50544.1 - 6.5e-11 42.3 21.5 0.038 14.5 0.1 9.2 6 4 5 11 11 11 4 HEAT-like repeat HEAT PF02985.17 EPY50544.1 - 3.9e-10 38.9 17.0 0.73 10.0 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat Arm_2 PF04826.8 EPY50544.1 - 9.5e-09 34.7 10.7 0.0012 18.0 0.2 3.8 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 EPY50544.1 - 6.3e-08 31.0 2.1 8.8e-08 30.5 1.5 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.15 EPY50544.1 - 4.8e-07 28.4 21.6 3.8e-05 22.2 9.1 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 EPY50544.1 - 7.7e-07 28.5 9.9 0.0022 17.1 3.7 3.9 1 1 2 3 3 3 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EPY50544.1 - 0.011 16.1 1.7 4.2 7.8 0.0 3.5 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EPY50544.1 - 0.63 10.6 13.2 16 6.3 0.2 6.9 8 0 0 8 8 8 0 PBS lyase HEAT-like repeat DAO PF01266.19 EPY50545.1 - 4.1e-48 164.1 0.0 4.9e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPY50545.1 - 3e-06 27.2 0.1 0.005 16.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPY50545.1 - 8.6e-06 24.8 0.5 0.0035 16.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPY50545.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPY50545.1 - 9e-05 21.4 0.4 0.018 13.9 0.0 2.7 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EPY50545.1 - 0.00078 18.5 0.2 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPY50545.1 - 0.0013 18.8 0.4 0.081 12.9 0.3 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPY50545.1 - 0.0022 18.3 0.2 0.046 14.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPY50545.1 - 0.0065 15.5 0.1 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EPY50545.1 - 0.019 13.4 0.1 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EPY50545.1 - 0.027 14.2 0.7 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Saccharop_dh PF03435.13 EPY50545.1 - 0.056 12.4 0.1 0.11 11.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Lycopene_cycl PF05834.7 EPY50545.1 - 0.066 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 EPY50545.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain SH3_1 PF00018.23 EPY50546.1 - 5.5e-06 25.6 0.0 1.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPY50546.1 - 6.5e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Dynamin_N PF00350.18 EPY50547.1 - 5.9e-16 58.7 0.3 1.3e-14 54.4 0.0 3.2 2 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 EPY50547.1 - 4.2e-10 39.3 0.9 2.3e-09 36.9 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY50547.1 - 1.1e-09 38.2 0.0 6.1e-09 35.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPY50547.1 - 0.00031 20.2 0.0 0.78 9.2 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EPY50547.1 - 0.00094 19.6 0.1 1.6 9.2 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein cobW PF02492.14 EPY50547.1 - 0.0026 17.2 0.5 0.032 13.6 0.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EPY50547.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EPY50547.1 - 0.008 16.4 0.2 0.34 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain FeoB_N PF02421.13 EPY50547.1 - 0.012 14.8 0.2 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B NBP1 PF08537.5 EPY50547.1 - 0.016 14.4 1.0 0.016 14.4 0.7 2.2 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 AAA_22 PF13401.1 EPY50547.1 - 0.087 12.9 0.0 7.9 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Arrestin_C PF02752.17 EPY50548.1 - 2.6e-14 53.4 0.0 5.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPY50548.1 - 2.2e-08 34.0 0.1 1.9e-07 31.0 0.1 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF3916 PF13079.1 EPY50548.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) Cullin_binding PF03556.10 EPY50549.1 - 2.1e-28 98.8 0.7 4.9e-28 97.6 0.5 1.6 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EPY50549.1 - 0.065 12.7 0.1 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain Ribosomal_L2_C PF03947.13 EPY50550.1 - 1.1e-37 128.7 3.9 1.2e-37 128.6 2.1 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPY50550.1 - 2.5e-15 56.1 0.0 5.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.13 EPY50551.1 - 1.1e-37 128.7 3.9 1.2e-37 128.6 2.1 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPY50551.1 - 2.5e-15 56.1 0.0 5.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.13 EPY50552.1 - 1.1e-37 128.7 3.9 1.2e-37 128.6 2.1 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPY50552.1 - 2.5e-15 56.1 0.0 5.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S17e PF00833.13 EPY50553.1 - 1.6e-60 202.2 0.5 1.8e-60 202.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 zf-CSL PF05207.8 EPY50554.1 - 0.053 13.0 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 CSL zinc finger E1-E2_ATPase PF00122.15 EPY50555.1 - 3e-60 203.1 2.0 6.4e-60 202.0 1.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPY50555.1 - 7.4e-33 113.5 4.3 7.4e-33 113.5 3.0 2.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPY50555.1 - 1.9e-27 97.1 0.0 1.6e-26 94.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY50555.1 - 2.8e-19 68.8 0.0 5.9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EPY50555.1 - 4.4e-15 54.8 0.0 4.4e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPY50555.1 - 4.4e-15 56.3 0.0 9e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPY50555.1 - 8.5e-05 22.2 0.8 0.0013 18.3 0.6 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OppC_N PF12911.2 EPY50555.1 - 0.67 9.3 3.8 78 2.7 0.0 3.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C PigN PF04987.9 EPY50556.1 - 8.1e-119 397.1 46.1 9.9e-119 396.8 31.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EPY50556.1 - 7.9e-09 35.3 0.4 0.00014 21.3 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPY50556.1 - 2.1e-05 23.8 0.1 4.3e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EPY50556.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Rhodanese PF00581.15 EPY50557.1 - 8e-16 58.3 0.0 2.2e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Alpha_E1_glycop PF01589.11 EPY50557.1 - 0.0078 14.5 0.0 0.009 14.3 0.0 1.1 1 0 0 1 1 1 1 Alphavirus E1 glycoprotein Ribosomal_S21 PF01165.15 EPY50558.1 - 2.3e-16 58.9 3.3 2.3e-16 58.9 2.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 PWI PF01480.12 EPY50559.1 - 2.4e-08 33.9 0.2 6.6e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EPY50559.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UAA PF08449.6 EPY50560.1 - 1.5e-84 283.4 20.1 1.8e-84 283.2 13.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPY50560.1 - 6.7e-09 35.8 10.5 6.7e-09 35.8 7.3 3.1 2 2 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EPY50560.1 - 5.1e-05 22.5 5.3 0.037 13.1 0.1 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 EPY50560.1 - 7.5e-05 22.4 11.6 7.5e-05 22.4 8.0 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 EPY50560.1 - 0.00022 21.3 23.8 0.0038 17.4 1.1 3.4 2 2 1 3 3 3 2 Multidrug resistance efflux transporter RNA_pol_3_Rpc31 PF11705.3 EPY50561.1 - 2.2e-40 139.0 10.5 2.4e-40 138.9 7.3 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CENP-T PF15511.1 EPY50561.1 - 0.062 12.5 4.9 0.074 12.2 3.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TT_ORF2 PF02957.10 EPY50561.1 - 0.19 12.4 4.7 0.36 11.5 3.2 1.4 1 0 0 1 1 1 0 TT viral ORF2 Ribosomal_L13 PF00572.13 EPY50562.1 - 1.8e-26 92.7 0.0 4.2e-26 91.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 Methyltransf_31 PF13847.1 EPY50563.1 - 3.2e-22 78.7 0.0 4.4e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY50563.1 - 1.7e-15 57.5 0.0 2.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY50563.1 - 5.6e-09 36.0 0.0 9.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY50563.1 - 8.3e-09 35.8 0.0 1.3e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY50563.1 - 4.7e-08 33.4 0.0 1.4e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY50563.1 - 8.3e-08 32.1 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY50563.1 - 1.5e-07 31.7 0.0 3e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPY50563.1 - 5.6e-06 26.1 0.0 6.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY50563.1 - 0.00019 20.8 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_20 PF12147.3 EPY50563.1 - 0.00048 19.0 0.0 0.00056 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EPY50563.1 - 0.0022 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EPY50563.1 - 0.0026 17.2 0.0 0.0037 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EPY50563.1 - 0.024 13.7 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EPY50563.1 - 0.037 13.0 0.0 0.069 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.12 EPY50563.1 - 0.083 11.9 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase GTP_EFTU_D3 PF03143.12 EPY50564.1 - 4.3e-37 126.2 0.1 8.8e-37 125.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPY50564.1 - 3.3e-08 33.5 0.5 5.5e-08 32.8 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.22 EPY50565.1 - 2.8e-57 193.1 0.1 3.6e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EPY50565.1 - 2.1e-16 59.8 1.2 2.1e-16 59.8 0.8 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPY50565.1 - 5.5e-05 22.7 0.3 0.00012 21.6 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPY50565.1 - 0.00095 19.1 0.7 0.0029 17.5 0.5 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FTHFS PF01268.14 EPY50566.1 - 2e-257 854.6 0.0 4.9e-257 853.3 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EPY50566.1 - 1.8e-67 225.3 2.7 2.6e-67 224.8 1.3 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EPY50566.1 - 2e-36 124.5 0.0 6.8e-36 122.8 0.0 2.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain FKBP_C PF00254.23 EPY50567.1 - 7.9e-33 112.3 0.0 9.2e-33 112.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AFG1_ATPase PF03969.11 EPY50568.1 - 1.7e-85 286.9 0.0 4.4e-80 269.2 0.0 2.9 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EPY50568.1 - 1.9e-05 24.7 0.0 0.0013 18.7 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain Bac_DnaA PF00308.13 EPY50568.1 - 0.0031 17.1 0.5 0.043 13.4 0.0 2.3 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.1 EPY50568.1 - 0.0044 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPY50568.1 - 0.0075 15.9 0.2 0.11 12.2 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EPY50568.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY50568.1 - 0.017 15.2 0.0 0.058 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPY50568.1 - 0.027 14.6 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase RNase_PH PF01138.16 EPY50569.1 - 8.2e-22 77.9 0.2 1.3e-21 77.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Rsbr_N PF08678.5 EPY50569.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.5 2 0 0 2 2 2 1 Rsbr N terminal Pyr_redox_2 PF07992.9 EPY50570.1 - 7.9e-26 91.1 0.0 2.8e-15 56.7 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPY50570.1 - 8.6e-11 42.0 0.0 3.8e-09 36.8 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPY50570.1 - 0.0074 16.3 0.4 0.38 10.7 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DFP PF04127.10 EPY50571.1 - 5.8e-21 74.9 0.0 1.8e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Cmc1 PF08583.5 EPY50572.1 - 6.9e-14 51.3 5.3 8.8e-14 51.0 3.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2099 PF09872.4 EPY50572.1 - 0.021 13.8 0.2 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) Pet191_N PF10203.4 EPY50572.1 - 0.073 13.1 4.5 0.99 9.4 0.4 2.2 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 EPY50572.1 - 0.093 12.6 2.2 0.14 12.1 0.6 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Ndufs5 PF10200.4 EPY50572.1 - 0.13 12.2 2.9 0.11 12.5 1.3 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa NDUF_B7 PF05676.8 EPY50572.1 - 0.26 10.7 2.5 0.41 10.1 1.7 1.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3128 PF11326.3 EPY50572.1 - 0.32 11.1 7.4 5.7 7.1 5.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) zf-CCHC PF00098.18 EPY50572.1 - 0.4 10.6 2.6 0.47 10.4 0.1 2.1 2 0 0 2 2 2 0 Zinc knuckle CHCH PF06747.8 EPY50572.1 - 2.2 8.2 9.3 1.1 9.2 3.2 2.5 2 1 1 3 3 3 0 CHCH domain Ubiq_cyt_C_chap PF03981.7 EPY50573.1 - 1.2e-32 112.6 0.3 1.7e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone TIP41 PF04176.8 EPY50574.1 - 2.3e-55 186.6 0.1 2.8e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family PH_7 PF15408.1 EPY50575.1 - 5.5e-19 67.9 0.0 1.3e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPY50575.1 - 3.7e-08 33.4 0.0 9.3e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PRCC PF10253.4 EPY50576.1 - 6.2e-13 49.8 3.0 6.2e-13 49.8 2.1 3.2 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting MatE PF01554.13 EPY50577.1 - 3e-62 209.0 28.9 1.1e-32 112.8 9.0 2.6 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EPY50577.1 - 5.9e-06 26.1 11.1 5.9e-06 26.1 7.7 4.1 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain SET PF00856.23 EPY50578.1 - 2.1e-10 41.1 0.1 3.6e-09 37.1 0.0 2.4 1 1 1 2 2 2 1 SET domain BolA PF01722.13 EPY50579.1 - 8.5e-09 35.2 0.0 1.1e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 BolA-like protein Orn_Arg_deC_N PF02784.11 EPY50579.1 - 0.018 14.2 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Cupin_5 PF06172.6 EPY50579.1 - 0.06 13.2 0.1 0.096 12.5 0.0 1.3 1 1 0 1 1 1 0 Cupin superfamily (DUF985) Ins_P5_2-kin PF06090.7 EPY50580.1 - 5.4e-40 137.3 2.1 8.4e-40 136.7 0.1 2.3 2 1 0 2 2 2 1 Inositol-pentakisphosphate 2-kinase BAR PF03114.13 EPY50580.1 - 0.038 13.5 0.2 0.068 12.6 0.2 1.4 1 0 0 1 1 1 0 BAR domain Syntaxin-6_N PF09177.6 EPY50580.1 - 0.18 12.2 2.2 0.34 11.3 0.2 2.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Ribosomal_L12 PF00542.14 EPY50581.1 - 3.5e-21 74.9 8.4 8.2e-20 70.5 2.8 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain CRAL_TRIO_2 PF13716.1 EPY50581.1 - 0.19 11.6 0.7 0.36 10.7 0.1 1.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Ribosomal_60s PF00428.14 EPY50581.1 - 0.38 11.1 9.1 0.059 13.7 2.3 2.3 2 1 0 2 2 2 0 60s Acidic ribosomal protein CTK3 PF12243.3 EPY50582.1 - 3.9e-50 169.1 0.0 6.2e-50 168.4 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EPY50582.1 - 7.9e-17 61.0 2.8 1.9e-16 59.8 1.9 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Nro1 PF12753.2 EPY50583.1 - 7.8e-66 222.6 3.6 1.4e-64 218.5 2.5 2.0 1 1 0 1 1 1 1 Nuclear pore complex subunit Nro1 Ephrin_lbd PF01404.14 EPY50583.1 - 0.017 14.9 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain URO-D PF01208.12 EPY50584.1 - 6.4e-130 433.0 0.0 7.2e-130 432.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) cNMP_binding PF00027.24 EPY50585.1 - 3.3e-36 122.9 0.0 4.1e-16 58.5 0.0 4.5 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EPY50585.1 - 3e-18 66.4 5.5 3.5e-17 63.0 3.8 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase NfeD PF01957.13 EPY50585.1 - 0.042 13.9 0.1 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF21 PF01595.15 EPY50586.1 - 3.7e-32 111.0 0.1 5.7e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EPY50586.1 - 0.012 15.4 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 CBS domain DUF972 PF06156.8 EPY50586.1 - 1.8 8.9 5.8 13 6.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Got1 PF04178.7 EPY50587.1 - 1.4e-18 67.0 12.9 1.6e-18 66.8 8.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3778 PF12620.3 EPY50587.1 - 0.1 12.2 0.3 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) CAAD PF14159.1 EPY50587.1 - 4.6 6.9 7.9 3.3 7.4 0.5 2.3 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF4405 PF14358.1 EPY50587.1 - 6.1 7.0 8.3 0.84 9.8 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4405) Rhodanese PF00581.15 EPY50588.1 - 8.6e-26 90.5 0.0 2.2e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain SNF2_N PF00176.18 EPY50589.1 - 2e-74 250.0 0.0 3.9e-74 249.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY50589.1 - 3e-14 52.6 0.0 8.9e-14 51.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY50589.1 - 0.00052 19.5 0.0 0.044 13.2 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase efThoc1 PF11957.3 EPY50590.1 - 5.4e-101 338.5 1.0 5.4e-101 338.5 0.7 1.9 1 1 1 2 2 2 1 THO complex subunit 1 transcription elongation factor CHCH PF06747.8 EPY50591.1 - 4e-07 29.7 5.6 5.9e-07 29.2 3.9 1.3 1 0 0 1 1 1 1 CHCH domain EHN PF06441.7 EPY50591.1 - 0.034 14.0 0.6 0.04 13.8 0.4 1.1 1 0 0 1 1 1 0 Epoxide hydrolase N terminus RRM_5 PF13893.1 EPY50592.1 - 2.9e-07 30.2 0.0 7.1e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY50592.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY50592.1 - 0.00036 20.2 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 EPY50592.1 - 0.0023 17.8 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPY50592.1 - 0.079 12.8 0.1 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif DSHCT PF08148.7 EPY50593.1 - 2.8e-56 189.6 0.3 6.5e-56 188.4 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPY50593.1 - 2.1e-20 72.9 1.5 5.5e-20 71.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY50593.1 - 6.7e-06 25.8 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pox_Ag35 PF03286.9 EPY50593.1 - 0.09 12.2 2.4 0.081 12.4 0.1 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GPI2 PF06432.6 EPY50594.1 - 2.2e-92 309.4 23.9 2.4e-92 309.2 16.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Cpn10 PF00166.16 EPY50595.1 - 3.2e-24 84.6 0.0 3.6e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit SMC_Nse1 PF07574.8 EPY50596.1 - 2.1e-14 53.6 0.1 1.2e-11 44.6 0.1 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EPY50596.1 - 0.093 12.7 16.5 0.19 11.7 11.4 1.5 1 0 0 1 1 1 0 RING-like domain Mga PF05043.8 EPY50596.1 - 0.098 12.9 0.1 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Mga helix-turn-helix domain DASH_Dad4 PF08650.5 EPY50596.1 - 0.14 12.1 0.5 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 Amidase PF01425.16 EPY50597.1 - 8.9e-112 374.1 0.0 7.9e-111 371.0 0.0 1.9 2 0 0 2 2 2 1 Amidase V-ATPase_H_N PF03224.9 EPY50597.1 - 0.16 11.0 0.1 4.9 6.1 0.0 2.1 2 0 0 2 2 2 0 V-ATPase subunit H Acetyltransf_7 PF13508.1 EPY50598.1 - 2.1e-06 27.7 0.0 5.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY50598.1 - 0.0019 18.0 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPY50598.1 - 0.0039 17.1 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPY50598.1 - 0.0061 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pex24p PF06398.6 EPY50599.1 - 2.9e-36 124.9 7.8 2.4e-35 121.9 5.4 1.9 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Aldedh PF00171.17 EPY50600.1 - 7.8e-158 525.6 0.0 9.6e-158 525.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPY50600.1 - 0.03 13.0 0.0 5.7 5.5 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) IBN_N PF03810.14 EPY50601.1 - 7.4e-19 67.4 2.2 1.1e-17 63.6 0.6 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 EPY50601.1 - 1.5e-10 40.2 0.1 1.1e-08 34.0 0.0 2.6 2 1 0 2 2 2 2 Cse1 HEAT_2 PF13646.1 EPY50601.1 - 0.0027 17.9 0.3 1.6 9.1 0.0 3.1 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EPY50601.1 - 0.0096 15.9 0.1 0.095 12.8 0.0 2.9 1 0 0 1 1 1 1 HEAT repeat DUF2435 PF10363.4 EPY50601.1 - 0.037 13.9 1.0 0.35 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EPY50601.1 - 0.31 11.5 3.9 2.2 8.8 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat Actin PF00022.14 EPY50602.1 - 1.6e-73 247.4 0.0 1.8e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Actin Dfp1_Him1_M PF08630.5 EPY50603.1 - 9.5e-40 135.2 0.0 3.5e-39 133.4 0.0 2.0 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EPY50603.1 - 4.8e-23 80.5 1.3 8.7e-23 79.7 0.9 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EPY50603.1 - 8.5e-06 25.8 0.1 2.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPY50603.1 - 5.2e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain zf-C2H2_2 PF12756.2 EPY50603.1 - 0.016 15.3 0.1 0.04 14.0 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) KH_1 PF00013.24 EPY50604.1 - 1.2e-94 309.9 54.1 6.2e-12 44.9 0.8 14.8 14 2 0 14 14 14 12 KH domain KH_3 PF13014.1 EPY50604.1 - 7.1e-60 197.8 39.6 6.9e-08 31.9 0.0 13.8 13 0 0 13 13 13 12 KH domain KH_2 PF07650.12 EPY50604.1 - 2.9e-06 26.7 38.4 0.1 12.1 0.7 10.2 9 2 2 11 11 11 5 KH domain zf-C2H2_2 PF12756.2 EPY50605.1 - 1.3e-36 124.7 12.7 2.8e-31 107.6 0.6 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EPY50605.1 - 2.1e-12 46.7 22.4 7.6e-05 22.7 1.8 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPY50605.1 - 1.3e-07 31.5 26.4 6.9e-06 26.0 1.5 4.7 5 0 0 5 5 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPY50605.1 - 5.3e-07 29.5 22.4 0.025 14.9 0.6 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type DUF629 PF04780.7 EPY50605.1 - 1.2e-05 24.1 4.8 0.002 16.7 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 EPY50605.1 - 0.0011 19.0 19.9 0.42 11.0 1.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPY50605.1 - 0.0012 18.6 19.6 0.0048 16.7 0.6 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger Pal1 PF08316.6 EPY50605.1 - 0.033 14.6 0.1 0.033 14.6 0.1 2.4 3 0 0 3 3 2 0 Pal1 cell morphology protein zf-LYAR PF08790.6 EPY50605.1 - 0.22 11.2 0.1 0.22 11.2 0.1 4.3 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger CCDC84 PF14968.1 EPY50605.1 - 0.25 10.8 11.9 0.11 11.9 6.4 1.7 1 1 0 2 2 2 0 Coiled coil protein 84 zf-C2HC5 PF06221.8 EPY50605.1 - 0.63 9.8 3.8 9.5 6.0 0.1 3.2 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-FCS PF06467.9 EPY50605.1 - 1.2 8.8 7.9 12 5.6 0.1 3.7 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif AKAP95 PF04988.7 EPY50605.1 - 3.4 7.4 11.9 2 8.1 0.3 3.8 3 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) STAG PF08514.6 EPY50606.1 - 8.4e-07 28.7 0.0 4.8e-06 26.2 0.0 2.3 1 0 0 1 1 1 1 STAG domain Cyclin_N PF00134.18 EPY50607.1 - 8.1e-38 128.8 0.2 1.4e-37 128.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPY50607.1 - 5e-28 97.4 0.1 9.9e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PGP_phosphatase PF09419.5 EPY50608.1 - 1.2e-55 187.4 0.0 1.4e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EPY50608.1 - 0.00021 20.9 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.5 EPY50609.1 - 1.3e-55 187.2 0.0 1.6e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EPY50609.1 - 0.00017 21.2 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Fe-S_biosyn PF01521.15 EPY50610.1 - 1.2e-19 70.2 0.0 1.6e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MCP_N PF05581.7 EPY50610.1 - 0.0073 16.4 0.0 0.75 9.9 0.0 2.2 2 0 0 2 2 2 2 Vibrio chemotaxis protein N terminus MAGE PF01454.14 EPY50611.1 - 6.9e-26 90.7 0.0 9.5e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 MAGE family SAM_2 PF07647.12 EPY50611.1 - 0.035 13.9 0.1 0.56 10.1 0.1 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Myosin_head PF00063.16 EPY50612.1 - 4.5e-250 831.4 3.7 4.5e-250 831.4 2.5 2.8 2 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 EPY50612.1 - 1.9e-08 33.8 0.5 6.4e-08 32.1 0.4 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 EPY50612.1 - 0.058 13.3 4.5 0.09 12.7 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 EPY50612.1 - 0.062 13.4 5.1 0.22 11.6 0.0 4.4 4 1 0 4 4 4 0 AAA domain IQ PF00612.22 EPY50612.1 - 0.063 12.9 1.6 0.16 11.6 1.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_19 PF13245.1 EPY50612.1 - 0.075 12.8 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain CNH PF00780.17 EPY50613.1 - 1.1e-47 162.7 0.0 1.6e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EPY50613.1 - 7.7e-34 117.1 0.1 1.3e-33 116.3 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EPY50613.1 - 3.7e-16 59.2 0.1 1.5e-15 57.3 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPY50613.1 - 1.5e-05 25.0 0.2 7e-05 22.9 0.1 2.3 1 0 0 1 1 1 1 PH domain CNH PF00780.17 EPY50614.1 - 2.2e-84 283.1 0.0 3.7e-84 282.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EPY50614.1 - 1.1e-36 125.7 0.0 3.8e-36 123.9 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EPY50614.1 - 1.7e-32 112.7 0.3 2.7e-32 112.0 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EPY50614.1 - 2.8e-12 46.2 0.0 5.2e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SNase PF00565.12 EPY50615.1 - 1.3e-53 179.8 0.0 9.9e-16 57.9 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EPY50615.1 - 9.8e-23 80.3 0.0 2.5e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Tudor domain Ribosomal_L37 PF08561.5 EPY50616.1 - 5.6e-19 67.4 3.2 1.2e-17 63.1 2.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 PolyA_pol PF01743.15 EPY50617.1 - 2.7e-21 76.0 0.1 4.8e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EPY50617.1 - 6.7e-06 25.5 0.0 3.1e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EPY50617.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative MU117 PF15474.1 EPY50618.1 - 5.8e-25 87.6 7.2 7.8e-25 87.2 5.0 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family TFIIS_M PF07500.9 EPY50620.1 - 2.1e-24 85.8 0.5 5.1e-24 84.5 0.4 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EPY50620.1 - 3.9e-14 53.1 0.0 8.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EPY50620.1 - 1.8e-09 37.1 11.0 3.1e-09 36.3 7.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 EPY50620.1 - 0.094 12.4 5.7 0.21 11.3 4.0 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.1 EPY50620.1 - 0.23 10.8 7.7 0.41 10.0 5.4 1.4 1 0 0 1 1 1 0 PHD-finger TPR_11 PF13414.1 EPY50621.1 - 1.2e-53 178.6 27.5 2.1e-19 68.9 1.8 6.3 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EPY50621.1 - 3.4e-40 134.0 31.3 4.7e-07 29.1 0.7 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EPY50621.1 - 5e-33 110.3 29.9 9.9e-06 25.1 0.4 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50621.1 - 2.4e-19 69.0 19.7 1.4e-10 40.9 3.3 6.1 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPY50621.1 - 6.9e-17 61.6 17.7 0.0032 18.1 0.1 6.4 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPY50621.1 - 4.8e-15 54.6 14.0 0.18 12.5 0.1 7.5 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EPY50621.1 - 2.7e-13 48.6 26.4 0.0062 16.2 0.0 7.9 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPY50621.1 - 2.9e-13 49.9 11.0 0.054 13.8 0.4 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPY50621.1 - 1.3e-12 46.8 14.3 0.016 15.3 0.1 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPY50621.1 - 1.4e-11 43.2 7.7 2.2e-05 23.9 0.0 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPY50621.1 - 2.8e-08 33.5 1.2 0.23 11.3 0.0 5.1 2 2 4 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EPY50621.1 - 0.0013 18.7 17.9 0.077 13.1 0.6 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EPY50621.1 - 0.0021 17.9 7.4 0.51 10.3 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPY50621.1 - 0.0051 17.1 16.7 0.52 10.8 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat MIT PF04212.13 EPY50621.1 - 0.039 13.8 12.0 0.43 10.5 0.4 4.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 EPY50621.1 - 0.16 11.3 7.4 2.7 7.3 0.0 4.1 3 1 2 5 5 5 0 26S proteasome subunit RPN7 TPR_4 PF07721.9 EPY50621.1 - 0.2 12.1 3.1 58 4.5 0.2 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPY50621.1 - 1.2 9.0 9.7 5.4 6.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Oxysterol_BP PF01237.13 EPY50622.1 - 5.3e-85 285.0 0.0 6.7e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Alb1 PF09135.6 EPY50623.1 - 7.5e-07 29.7 16.2 8.8e-07 29.5 11.2 1.1 1 0 0 1 1 1 1 Alb1 DUF1974 PF09317.6 EPY50623.1 - 0.093 12.1 2.1 0.11 11.8 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) MDFI PF15316.1 EPY50623.1 - 1.2 9.1 4.2 1.4 8.8 2.9 1.1 1 0 0 1 1 1 0 MyoD family inhibitor PI3_PI4_kinase PF00454.22 EPY50624.1 - 2.8e-42 144.8 0.1 8.7e-42 143.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EPY50624.1 - 7e-24 84.3 2.5 7.9e-23 80.9 0.8 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EPY50624.1 - 1.1e-07 31.1 0.0 2.9e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 FATC domain CRAL_TRIO PF00650.15 EPY50625.1 - 7.3e-40 136.0 0.0 1.3e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPY50625.1 - 4e-10 39.6 0.3 1.1e-09 38.3 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPY50625.1 - 0.00068 19.5 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Rep_fac-A_3 PF08661.6 EPY50626.1 - 2.7e-25 88.3 0.1 3.2e-25 88.1 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.1 EPY50626.1 - 0.11 12.0 0.1 9 5.9 0.0 2.1 1 1 1 2 2 2 0 Telomere-capping, CST complex subunit RNB PF00773.14 EPY50627.1 - 1.1e-52 179.4 0.0 1.5e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain DUF4558 PF15104.1 EPY50628.1 - 0.1 12.5 1.3 0.2 11.6 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) TRP PF06011.7 EPY50629.1 - 2.3e-54 184.6 35.9 9.3e-54 182.6 24.9 1.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPY50629.1 - 1.4e-10 41.3 0.0 2.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 ML-like domain UDPGP PF01704.13 EPY50630.1 - 6.4e-192 637.6 2.0 7.5e-192 637.4 1.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Peptidase_M1 PF01433.15 EPY50631.1 - 1.6e-78 264.5 0.0 2e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EPY50631.1 - 5.1e-46 155.8 0.0 8.5e-46 155.1 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EPY50631.1 - 2.4e-14 53.4 0.0 4.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EPY50631.1 - 0.084 12.8 0.6 0.57 10.1 0.4 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase IBN_N PF03810.14 EPY50632.1 - 6e-14 51.7 1.1 1.9e-13 50.1 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPY50632.1 - 6.5e-07 29.3 0.1 6.5e-07 29.3 0.1 5.0 5 0 0 5 5 5 1 Exportin 1-like protein EntA_Immun PF08951.5 EPY50632.1 - 0.099 12.8 1.5 4.3 7.5 0.1 3.1 2 0 0 2 2 2 0 Enterocin A Immunity Pkinase PF00069.20 EPY50633.1 - 1.8e-66 223.9 0.0 2.4e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50633.1 - 6.6e-28 97.4 0.0 1.5e-27 96.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50633.1 - 0.0001 21.3 0.5 0.12 11.2 0.1 3.1 3 1 0 3 3 3 2 Kinase-like DUF2413 PF10310.4 EPY50634.1 - 8.6e-86 288.4 8.3 1.2e-85 287.9 5.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) FTP PF07504.8 EPY50634.1 - 0.062 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Ndc1_Nup PF09531.5 EPY50634.1 - 0.17 10.2 6.7 0.17 10.2 2.8 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF1183 PF06682.7 EPY50634.1 - 1.8 8.0 4.9 0.54 9.7 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Allexi_40kDa PF05549.6 EPY50634.1 - 5.8 6.1 8.8 11 5.2 1.6 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein GPI-anchored PF10342.4 EPY50636.1 - 1.1e-11 45.0 3.5 1.1e-11 45.0 2.4 2.6 2 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EPY50636.1 - 0.32 10.4 2.7 1.6 8.2 1.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Ribosomal_L14 PF00238.14 EPY50637.1 - 5e-35 119.9 0.0 5.6e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Mad3_BUB1_I PF08311.7 EPY50638.1 - 8.6e-30 103.1 0.4 1.6e-29 102.2 0.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EPY50638.1 - 4.1e-12 45.8 0.0 7.4e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50638.1 - 8.3e-07 28.3 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ELFV_dehydrog PF00208.16 EPY50639.1 - 1.8e-60 204.5 0.1 2.9e-60 203.8 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EPY50639.1 - 8.5e-16 56.6 0.1 3.5e-10 38.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EPY50639.1 - 8e-05 22.2 0.0 0.00031 20.3 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SIR2 PF02146.12 EPY50640.1 - 2.2e-38 131.7 0.0 2.4e-34 118.6 0.0 2.4 1 1 1 2 2 2 2 Sir2 family CutC PF03932.9 EPY50640.1 - 0.0043 16.3 0.0 0.0097 15.1 0.0 1.6 1 0 0 1 1 1 1 CutC family MCPVI PF02993.9 EPY50640.1 - 0.034 14.2 4.0 0.051 13.7 2.8 1.2 1 0 0 1 1 1 0 Minor capsid protein VI RP-C_C PF11800.3 EPY50640.1 - 0.48 10.0 4.3 0.75 9.4 2.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region FbpA PF05833.6 EPY50641.1 - 1.8e-34 119.1 12.1 1.8e-34 119.1 8.4 3.4 2 2 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 EPY50641.1 - 3.1e-22 78.2 0.5 1.3e-21 76.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EPY50641.1 - 9.8e-20 70.2 0.0 2.9e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Band_7 PF01145.20 EPY50642.1 - 2.1e-21 76.6 0.2 2.8e-21 76.2 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_L34e PF01199.13 EPY50643.1 - 4.1e-38 129.5 1.1 5.5e-38 129.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e VTC PF09359.5 EPY50644.1 - 9e-100 333.3 0.5 1.4e-99 332.6 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EPY50644.1 - 1.9e-26 93.4 17.1 3.7e-12 46.6 7.6 3.9 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EPY50644.1 - 6.4e-08 32.6 4.5 6.4e-08 32.6 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ATP-grasp PF02222.17 EPY50645.1 - 2.7e-65 218.9 0.0 4.1e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.15 EPY50645.1 - 1.1e-64 216.2 2.1 2.2e-64 215.2 1.5 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp_4 PF13535.1 EPY50645.1 - 2.3e-12 47.0 0.0 4.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EPY50645.1 - 1.9e-06 27.3 0.0 3.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EPY50645.1 - 0.0001 21.7 0.0 0.00031 20.1 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPY50645.1 - 0.0061 15.3 0.0 0.99 8.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CoA_binding_2 PF13380.1 EPY50645.1 - 0.025 14.7 0.2 5.9 7.1 0.0 2.8 1 1 1 2 2 2 0 CoA binding domain Fic PF02661.13 EPY50645.1 - 0.092 13.4 0.1 10 6.8 0.0 3.4 2 1 1 3 3 3 0 Fic/DOC family Aldo_ket_red PF00248.16 EPY50648.1 - 3.4e-46 157.3 0.0 4.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RING_2 PF13639.1 EPY50649.1 - 9.7e-15 54.1 6.3 9.7e-15 54.1 4.4 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY50649.1 - 8.3e-10 38.1 10.7 1.5e-09 37.3 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY50649.1 - 1e-08 35.0 7.0 1e-08 35.0 4.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY50649.1 - 1.1e-07 31.4 5.7 1.1e-07 31.4 3.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPY50649.1 - 1.5e-07 31.4 1.7 1.5e-07 31.4 1.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPY50649.1 - 2e-05 24.1 7.1 2e-05 24.1 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EPY50649.1 - 0.013 15.4 5.6 0.07 13.1 3.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_3 PF14369.1 EPY50649.1 - 0.018 15.0 4.0 0.065 13.2 2.8 2.0 1 0 0 1 1 1 0 zinc-finger zf-Apc11 PF12861.2 EPY50649.1 - 0.02 14.7 3.6 0.073 12.9 2.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EPY50649.1 - 0.038 13.7 10.0 0.03 14.0 2.1 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EPY50649.1 - 0.039 13.6 2.5 0.15 11.7 1.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger HypA PF01155.14 EPY50649.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Baculo_RING PF05883.6 EPY50649.1 - 0.17 11.6 1.0 0.42 10.4 0.7 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zinc-ribbons_6 PF07191.7 EPY50649.1 - 7.6 6.4 8.8 0.29 10.9 0.2 2.4 2 1 0 2 2 2 0 zinc-ribbons Fis1_TPR_C PF14853.1 EPY50650.1 - 1.8e-05 24.4 0.4 2.8e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EPY50650.1 - 0.014 14.6 0.4 0.07 12.4 0.2 2.0 1 1 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EPY50650.1 - 0.027 14.3 0.1 0.09 12.7 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L18p PF00861.17 EPY50651.1 - 2.6e-43 147.0 0.1 8.3e-43 145.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EPY50651.1 - 7.2e-30 103.4 3.0 7.2e-30 103.4 2.1 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EPY50651.1 - 0.08 12.9 0.1 0.28 11.2 0.1 2.0 1 1 0 1 1 1 0 Threonine synthase N terminus RRM_1 PF00076.17 EPY50652.1 - 2.3e-12 46.3 0.0 3.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50652.1 - 9.5e-09 34.9 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50652.1 - 9.8e-05 22.2 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY50652.1 - 0.00075 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L18e PF00828.14 EPY50653.1 - 3.2e-28 98.6 0.3 3.2e-28 98.6 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 KRE9 PF05390.6 EPY50655.1 - 1.5e-07 31.6 4.6 3.1e-07 30.6 3.2 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 TFCD_C PF12612.3 EPY50656.1 - 2.5e-09 36.8 10.8 1.4e-08 34.4 0.1 4.1 5 0 0 5 5 5 2 Tubulin folding cofactor D C terminal HEAT PF02985.17 EPY50656.1 - 0.0025 17.7 5.4 2.1 8.6 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EPY50656.1 - 0.0066 16.9 1.0 14 6.3 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat Ndc80_HEC PF03801.8 EPY50657.1 - 2e-50 170.3 1.1 4.5e-50 169.2 0.0 2.1 2 0 0 2 2 2 1 HEC/Ndc80p family Reo_sigmaC PF04582.7 EPY50657.1 - 0.00014 21.1 11.1 0.0041 16.3 0.6 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Leu_zip PF15294.1 EPY50657.1 - 0.057 12.5 50.0 0.28 10.2 9.7 2.1 2 0 0 2 2 2 0 Leucine zipper Atg14 PF10186.4 EPY50657.1 - 0.096 11.6 42.6 0.028 13.3 6.2 3.1 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EPY50657.1 - 0.2 11.4 47.9 0.21 11.3 6.9 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.7 EPY50657.1 - 0.7 10.3 24.2 0.064 13.6 0.9 4.4 2 2 1 3 3 3 0 SlyX GDPD PF03009.12 EPY50657.1 - 3.6 7.0 9.5 0.46 9.9 3.3 1.9 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family MscS_porin PF12795.2 EPY50657.1 - 4.4 6.5 47.9 0.63 9.3 8.4 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FCH PF00611.18 EPY50658.1 - 9.8e-20 70.5 0.2 4e-19 68.6 0.1 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EPY50658.1 - 9.5e-12 44.1 0.2 1.8e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPY50658.1 - 2.2e-11 43.1 0.1 4.1e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPY50658.1 - 5.3e-10 38.6 0.1 9.6e-10 37.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CENP-F_leu_zip PF10473.4 EPY50658.1 - 0.55 10.0 6.3 4.2 7.2 1.1 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4110 PF13422.1 EPY50658.1 - 4.2 7.2 8.4 0.35 10.7 0.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) Tet_JBP PF12851.2 EPY50659.1 - 0.04 13.2 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily zf-MIZ PF02891.15 EPY50660.1 - 0.064 12.7 0.3 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger DEAD PF00270.24 EPY50661.1 - 9.9e-46 155.3 0.0 5e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY50661.1 - 4.4e-27 93.7 0.0 3e-26 91.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EPY50661.1 - 0.0035 16.4 0.0 0.0035 16.4 0.0 2.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Vfa1 PF08432.5 EPY50661.1 - 1.2 9.1 24.1 1.9 8.4 16.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.10 EPY50661.1 - 1.2 7.6 11.0 3.1 6.3 6.1 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF755 PF05501.6 EPY50661.1 - 1.3 9.0 22.5 2.6 8.1 15.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Neur_chan_memb PF02932.11 EPY50661.1 - 2.1 8.1 4.7 3.2 7.5 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 EPY50661.1 - 2.6 5.6 10.7 3.9 5.0 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN9 PF10680.4 EPY50663.1 - 9.3e-09 34.9 0.2 3.1e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RNase_PH PF01138.16 EPY50664.1 - 1.4e-25 90.1 0.0 2.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPY50664.1 - 2.4e-09 36.9 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Diphthamide_syn PF01866.12 EPY50665.1 - 3.9e-73 246.3 0.0 5e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MoeZ_MoeB PF05237.8 EPY50665.1 - 0.0031 17.0 0.0 0.0084 15.6 0.0 1.7 2 0 0 2 2 2 1 MoeZ/MoeB domain DUF3020 PF11223.3 EPY50666.1 - 8.1e-22 77.3 8.8 8.1e-22 77.3 6.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) DUF1675 PF07897.6 EPY50666.1 - 0.0024 17.8 3.8 0.0045 16.8 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) WD40 PF00400.27 EPY50667.1 - 7e-14 51.0 17.7 2.2e-05 24.1 0.4 6.0 7 1 0 7 7 7 4 WD domain, G-beta repeat PC_rep PF01851.17 EPY50668.1 - 4.6e-38 127.3 17.9 1.7e-06 27.9 0.0 9.3 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPY50668.1 - 3.8e-11 43.1 2.9 2.7e-07 30.7 0.1 4.1 2 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EPY50668.1 - 0.00023 21.5 0.1 5.8 7.5 0.0 4.6 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EPY50668.1 - 0.00038 20.3 0.4 0.79 9.9 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_PBS PF03130.11 EPY50668.1 - 0.07 13.6 0.4 7.1 7.4 0.0 3.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Rod_C PF10493.4 EPY50668.1 - 0.13 10.5 0.5 0.83 7.8 0.1 2.0 2 0 0 2 2 2 0 Rough deal protein C-terminal region Ank_5 PF13857.1 EPY50668.1 - 0.18 12.1 1.2 0.72 10.1 0.0 2.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) TPR_2 PF07719.12 EPY50668.1 - 0.53 10.3 2.6 0.68 9.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_primase_lrg PF04104.9 EPY50669.1 - 3.2e-87 292.0 0.0 4.9e-87 291.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PCI PF01399.22 EPY50670.1 - 5.4e-07 29.8 0.4 7.4e-06 26.2 0.1 3.0 2 0 0 2 2 2 1 PCI domain zf-HC5HC2H_2 PF13832.1 EPY50671.1 - 7.6e-27 93.4 22.0 1.2e-26 92.8 8.9 2.4 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPY50671.1 - 2.2e-20 72.6 8.8 2.2e-20 72.6 6.1 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EPY50671.1 - 2.6e-13 49.0 3.3 2.6e-13 49.0 2.3 3.2 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 EPY50671.1 - 6e-09 35.4 9.6 6e-09 35.4 6.6 3.3 4 0 0 4 4 4 1 PHD-finger EPL1 PF10513.4 EPY50671.1 - 8.3e-05 22.8 0.9 0.00018 21.7 0.0 2.0 2 0 0 2 2 2 1 Enhancer of polycomb-like C1_1 PF00130.17 EPY50671.1 - 0.0026 17.4 2.0 0.0026 17.4 1.4 3.6 4 0 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CMD PF02627.15 EPY50672.1 - 1.5e-07 31.1 0.0 3.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family zf-rbx1 PF12678.2 EPY50673.1 - 4.4e-12 45.9 1.9 9e-12 44.9 1.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPY50673.1 - 1.3e-09 37.6 9.6 1.3e-09 37.6 6.7 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY50673.1 - 8.5e-08 31.7 5.5 2e-06 27.3 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY50673.1 - 5.4e-06 25.9 5.1 1.1e-05 24.9 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY50673.1 - 8e-06 25.4 6.3 5.6e-05 22.7 4.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPY50673.1 - 1.4e-05 24.9 2.4 1.4e-05 24.9 1.7 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPY50673.1 - 0.001 18.7 5.6 0.001 18.7 3.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EPY50673.1 - 0.0015 18.2 6.6 0.011 15.6 4.6 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EPY50673.1 - 0.028 13.9 1.0 0.068 12.7 0.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Lsm_interact PF05391.6 EPY50673.1 - 0.12 11.8 0.5 4.2 6.9 0.1 2.5 2 0 0 2 2 2 0 Lsm interaction motif zf-RING_4 PF14570.1 EPY50673.1 - 0.15 11.6 3.1 0.14 11.7 0.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EPY50673.1 - 0.16 11.4 6.4 0.29 10.6 1.9 2.6 2 0 0 2 2 2 0 P-11 zinc finger FANCL_C PF11793.3 EPY50673.1 - 1.2 9.1 5.3 4.9 7.1 3.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EPY50673.1 - 1.7 8.5 8.8 0.17 11.8 0.8 2.7 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EPY50673.1 - 2.1 8.4 8.4 1.1 9.3 3.3 2.2 2 0 0 2 2 2 0 RING-variant domain Peptidase_C48 PF02902.14 EPY50674.1 - 7.3e-18 64.9 0.0 1.3e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cyclin PF08613.6 EPY50675.1 - 3.7e-42 144.2 0.8 6e-42 143.5 0.5 1.3 1 0 0 1 1 1 1 Cyclin LSM PF01423.17 EPY50676.1 - 5.2e-16 57.9 0.3 5.9e-16 57.7 0.2 1.0 1 0 0 1 1 1 1 LSM domain DUF2435 PF10363.4 EPY50677.1 - 7.2e-20 70.6 0.8 1.3e-18 66.6 0.1 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 EPY50677.1 - 1.3e-05 25.3 3.2 0.53 10.5 0.0 4.7 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EPY50677.1 - 0.0089 16.0 0.3 0.5 10.5 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat DUF4359 PF14271.1 EPY50677.1 - 0.076 13.4 0.0 0.42 11.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) GRAM PF02893.15 EPY50678.1 - 1.4e-20 72.5 0.0 3.2e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain HORMA PF02301.13 EPY50679.1 - 1.8e-41 141.9 0.3 2e-41 141.7 0.2 1.0 1 0 0 1 1 1 1 HORMA domain DUF2927 PF11150.3 EPY50679.1 - 0.0039 16.9 0.2 0.0057 16.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2927) ATG13 PF10033.4 EPY50679.1 - 0.024 14.0 0.1 0.08 12.3 0.1 1.8 1 1 0 1 1 1 0 Autophagy-related protein 13 NRDE-2 PF08424.5 EPY50680.1 - 2.7e-62 210.5 0.6 2.7e-62 210.5 0.4 2.5 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EPY50680.1 - 0.05 13.8 0.0 23 5.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Nse4_C PF08743.5 EPY50681.1 - 1.1e-26 92.6 0.1 4.3e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EPY50681.1 - 3.6e-08 33.1 0.0 6.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE IFRD PF05004.8 EPY50682.1 - 2.1e-64 217.5 4.3 2.8e-64 217.1 3.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF1741 PF08427.5 EPY50683.1 - 5.7e-41 140.5 0.6 5.7e-41 140.5 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) DUF4587 PF15248.1 EPY50683.1 - 0.048 14.2 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) Gar1 PF04410.9 EPY50684.1 - 1.3e-42 144.9 0.0 1.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EPY50685.1 - 5.9e-47 159.4 0.1 1.1e-46 158.5 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPY50685.1 - 4.4e-18 65.0 0.2 9.8e-18 63.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EPY50685.1 - 6.1e-15 54.8 0.0 1.4e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EPY50685.1 - 4.3e-12 45.7 0.0 8.9e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Vac14_Fig4_bd PF11916.3 EPY50686.1 - 2.9e-76 254.6 7.5 7.8e-76 253.2 5.2 1.8 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EPY50686.1 - 2.7e-45 152.7 6.6 3.3e-39 133.2 0.1 5.4 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EPY50686.1 - 6.9e-13 47.5 0.4 0.15 12.1 0.0 6.9 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 EPY50686.1 - 1.4e-06 28.4 0.0 2.9 8.2 0.0 5.3 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EPY50686.1 - 0.0011 19.4 0.1 17 6.0 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat ParcG PF10274.4 EPY50686.1 - 0.0042 16.9 2.5 0.15 11.9 0.1 3.0 3 0 0 3 3 3 1 Parkin co-regulated protein PSII PF00421.14 EPY50686.1 - 0.032 12.8 0.0 0.055 12.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein Tim17 PF02466.14 EPY50687.1 - 1.5e-40 138.1 3.3 1.9e-40 137.8 2.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 EPY50687.1 - 0.12 12.2 2.4 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) YIF1 PF03878.10 EPY50688.1 - 9.2e-96 319.6 3.8 1.1e-95 319.4 2.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EPY50688.1 - 0.00015 21.2 4.7 0.0003 20.3 3.3 1.5 1 1 0 1 1 1 1 Yip1 domain NAC PF01849.13 EPY50689.1 - 2.3e-16 59.0 1.5 8.6e-16 57.2 0.2 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EPY50689.1 - 0.00053 19.7 0.7 0.0011 18.7 0.5 1.6 1 0 0 1 1 1 1 UBA/TS-N domain eIF-1a PF01176.14 EPY50690.1 - 2.7e-27 93.9 0.2 3.9e-27 93.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CorA PF01544.13 EPY50691.1 - 1.4e-08 34.1 8.5 6.7e-08 31.9 5.9 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1690 PF07956.6 EPY50692.1 - 5.6e-36 123.6 6.3 6.3e-36 123.4 4.4 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.8 EPY50692.1 - 0.017 14.9 0.1 0.056 13.3 0.1 1.8 1 0 0 1 1 1 0 CHCH domain HDAC4_Gln PF12203.3 EPY50692.1 - 0.25 11.3 6.6 0.38 10.7 4.6 1.3 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 THUMP PF02926.12 EPY50693.1 - 7.7e-22 77.7 1.6 9.6e-22 77.4 0.5 1.6 1 1 1 2 2 2 1 THUMP domain EF_TS PF00889.14 EPY50693.1 - 0.045 13.0 0.0 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 Elongation factor TS Bromodomain PF00439.20 EPY50694.1 - 3.1e-18 65.4 0.1 1.1e-17 63.6 0.1 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EPY50694.1 - 1.3e-14 53.7 0.0 2.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Neur_chan_memb PF02932.11 EPY50694.1 - 1.1 9.0 12.1 0.28 11.0 3.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cpn60_TCP1 PF00118.19 EPY50695.1 - 1e-144 482.8 1.6 1.2e-144 482.5 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1744 PF08490.7 EPY50696.1 - 5.6e-141 469.6 6.8 8.7e-141 469.0 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EPY50696.1 - 4e-70 236.2 2.5 1.1e-69 234.8 1.7 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EPY50696.1 - 1.9e-24 86.2 0.0 6.3e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EPY50696.1 - 5.4e-10 39.1 0.1 1.8e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EPY50696.1 - 0.00039 20.2 1.9 0.0011 18.8 0.1 2.8 3 1 0 3 3 3 1 RNase_H superfamily zf-DNA_Pol PF08996.5 EPY50696.1 - 0.027 13.8 1.3 0.078 12.3 0.9 1.7 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger DUF3767 PF12597.3 EPY50697.1 - 1.5e-22 79.4 0.0 1.7e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3265 PF11665.3 EPY50697.1 - 0.34 10.7 4.1 0.54 10.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) UNC-50 PF05216.8 EPY50698.1 - 1.3e-79 266.7 16.9 1.5e-79 266.4 11.7 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1282 PF06930.7 EPY50698.1 - 0.096 12.3 11.4 0.23 11.1 7.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) PDCD2_C PF04194.8 EPY50699.1 - 1.2e-36 125.7 2.4 3.7e-36 124.1 0.0 2.3 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain VHS PF00790.14 EPY50700.1 - 4.3e-48 162.5 0.1 2e-47 160.3 0.0 2.2 3 0 0 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.15 EPY50700.1 - 2e-11 44.2 1.7 2e-11 44.2 1.2 1.7 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.9 EPY50700.1 - 2.3e-06 27.4 0.5 2.3e-06 27.4 0.3 2.5 3 0 0 3 3 3 1 GAT domain Ribosomal_S4e PF00900.15 EPY50701.1 - 7.4e-34 115.2 0.5 1.4e-33 114.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPY50701.1 - 9.2e-19 67.0 6.4 1.9e-18 65.9 4.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPY50701.1 - 6.9e-06 25.3 0.0 1.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPY50701.1 - 0.00074 19.1 0.4 0.00074 19.1 0.3 2.7 3 0 0 3 3 3 1 KOW motif Pkinase PF00069.20 EPY50702.1 - 5.6e-68 228.8 0.0 6.5e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50702.1 - 2.3e-28 98.9 0.0 4.2e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50702.1 - 7.7e-05 21.7 0.0 0.00031 19.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EPY50702.1 - 0.042 13.5 0.2 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPY50702.1 - 0.048 12.4 0.1 0.081 11.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Baculo_PEP_N PF04512.7 EPY50703.1 - 0.0094 15.9 0.2 0.041 13.8 0.1 2.0 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, N terminus AA_permease PF00324.16 EPY50704.1 - 2.7e-124 415.1 47.1 3.1e-124 414.9 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY50704.1 - 2.1e-37 128.6 49.0 2.6e-37 128.3 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease HPIH PF13323.1 EPY50704.1 - 0.02 14.6 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain with HPIH motif SNase PF00565.12 EPY50705.1 - 3.1e-25 88.5 0.0 4.1e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF1560 PF07597.6 EPY50705.1 - 0.56 10.2 2.3 34 4.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1560) ANTH PF07651.11 EPY50706.1 - 1.9e-66 223.6 0.1 2.6e-66 223.1 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EPY50706.1 - 4e-08 33.1 0.2 1.1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 ENTH domain Septin PF00735.13 EPY50707.1 - 2.3e-79 266.3 0.1 4e-79 265.5 0.1 1.4 1 0 0 1 1 1 1 Septin Pkinase PF00069.20 EPY50708.1 - 3.3e-71 239.4 0.3 5.6e-70 235.4 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50708.1 - 6.1e-50 169.7 0.0 1.3e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50708.1 - 0.0031 16.5 0.0 0.0067 15.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Arm PF00514.18 EPY50708.1 - 0.0091 15.7 3.1 1.3 8.9 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat ABC1 PF03109.11 EPY50708.1 - 0.023 14.6 0.0 0.093 12.6 0.0 2.0 2 0 0 2 2 2 0 ABC1 family Kelch_3 PF13415.1 EPY50709.1 - 4.6e-19 68.0 3.8 2.7e-09 36.9 0.0 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EPY50709.1 - 6.9e-19 67.1 5.5 6.5e-06 26.0 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EPY50709.1 - 2.5e-16 59.1 0.7 5.2e-08 32.5 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EPY50709.1 - 2.3e-13 49.3 1.8 0.00074 19.1 0.1 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 EPY50709.1 - 2e-11 43.2 8.9 0.0018 17.7 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EPY50709.1 - 2.3e-11 43.3 7.9 0.0018 18.1 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Med8 PF10232.4 EPY50710.1 - 1.4e-45 155.5 11.7 2.3e-45 154.8 8.2 1.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 EVE PF01878.13 EPY50711.1 - 8.7e-40 136.0 1.5 9.8e-40 135.8 0.1 1.7 2 0 0 2 2 2 1 EVE domain Peptidase_S49_N PF08496.5 EPY50711.1 - 0.52 10.0 3.3 0.75 9.5 2.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TLD PF07534.11 EPY50712.1 - 1.5e-21 76.8 0.1 1.4e-20 73.7 0.1 2.1 1 1 0 1 1 1 1 TLD AT_hook PF02178.14 EPY50713.1 - 0.066 12.9 2.7 0.21 11.3 1.9 1.9 1 0 0 1 1 1 0 AT hook motif Spc24 PF08286.6 EPY50713.1 - 2.1 8.0 8.0 0.24 11.0 1.7 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MAT1 PF06391.8 EPY50714.1 - 9.4e-60 201.6 20.0 1.2e-59 201.2 13.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EPY50714.1 - 0.0011 18.5 0.6 0.0011 18.5 0.4 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY50714.1 - 0.05 13.6 9.0 0.36 10.9 6.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3797 PF12677.2 EPY50714.1 - 0.097 12.3 1.4 0.21 11.2 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_4 PF14570.1 EPY50714.1 - 0.1 12.1 8.7 0.23 11.0 1.6 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EPY50714.1 - 0.11 12.3 8.4 0.82 9.4 5.9 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPY50714.1 - 0.14 11.8 9.1 0.99 9.1 6.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY50714.1 - 3.3 7.6 16.4 0.17 11.7 6.1 2.5 2 1 1 3 3 3 0 Ring finger domain RRP7 PF12923.2 EPY50715.1 - 6.5e-31 107.0 6.9 1.1e-30 106.3 4.8 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) DUF4250 PF14056.1 EPY50715.1 - 0.079 12.6 0.6 0.26 11.0 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Ribosomal_L14e PF01929.12 EPY50715.1 - 2.6 8.4 9.2 7 7.0 1.5 3.0 3 0 0 3 3 3 0 Ribosomal protein L14 DUF999 PF06198.6 EPY50717.1 - 0.078 12.7 1.2 0.17 11.6 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF999) EmrE PF13536.1 EPY50717.1 - 0.25 11.5 7.3 0.52 10.5 5.0 1.6 1 0 0 1 1 1 0 Multidrug resistance efflux transporter UCH PF00443.24 EPY50719.1 - 8.1e-43 146.4 0.6 1.2e-41 142.5 0.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY50719.1 - 6.1e-14 52.1 3.7 4e-12 46.1 2.6 3.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPY50719.1 - 8.2e-08 32.2 10.8 8.2e-08 32.2 7.5 2.8 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein TAF4 PF05236.9 EPY50720.1 - 9.7e-61 205.3 5.9 1.2e-60 205.0 4.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF1657 PF07870.6 EPY50720.1 - 0.061 13.0 0.2 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) DUF4337 PF14235.1 EPY50720.1 - 0.85 9.4 4.8 1.4 8.6 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.1 EPY50720.1 - 6.4 5.6 9.4 1.3 7.9 4.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SWIB PF02201.13 EPY50721.1 - 1.4e-22 79.1 0.0 4.3e-22 77.5 0.0 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain WGG PF10273.4 EPY50721.1 - 0.068 13.2 1.1 0.24 11.5 0.0 2.4 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 PCI PF01399.22 EPY50722.1 - 3e-21 75.7 0.2 3.2e-20 72.4 0.1 2.7 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EPY50722.1 - 6.9e-05 22.6 0.3 0.00022 20.9 0.1 2.0 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_16 PF13432.1 EPY50722.1 - 0.0022 18.5 5.8 0.16 12.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY50722.1 - 0.078 13.3 6.2 0.31 11.4 0.1 4.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPY50722.1 - 0.4 10.5 13.0 8.4 6.4 0.7 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPY50722.1 - 0.48 10.1 10.4 1.6 8.4 0.2 3.8 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.1 EPY50722.1 - 0.68 9.8 7.3 11 6.1 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPY50722.1 - 2.3 8.3 7.3 12 6.0 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50722.1 - 3.6 7.5 12.2 1.1 9.2 0.1 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat PDZ_1 PF12812.2 EPY50723.1 - 1.2e-41 140.4 0.0 6.8e-30 102.7 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EPY50723.1 - 6.2e-14 51.6 1.0 6.4e-06 25.9 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Trypsin_2 PF13365.1 EPY50723.1 - 2e-13 50.3 0.2 3.7e-11 43.0 0.0 2.8 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ PF00595.19 EPY50723.1 - 3.7e-07 30.2 0.4 0.072 13.2 0.0 4.0 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 EPY50723.1 - 0.0022 17.3 0.0 0.0053 16.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Tricorn_PDZ PF14685.1 EPY50723.1 - 0.0032 17.2 0.2 0.87 9.4 0.0 3.0 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S3 PF00944.14 EPY50723.1 - 0.069 12.5 0.1 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Alphavirus core protein DUF31 PF01732.11 EPY50723.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EPY50723.1 - 0.23 9.8 0.1 0.43 8.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 Baculo_VP91_N PF08475.5 EPY50724.1 - 0.036 13.4 2.6 0.049 12.9 1.8 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal YEATS PF03366.11 EPY50725.1 - 3.9e-26 90.6 0.5 6.2e-26 89.9 0.4 1.3 1 0 0 1 1 1 1 YEATS family Abhydrolase_6 PF12697.2 EPY50726.1 - 1.6e-29 103.4 0.0 2e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY50726.1 - 3.8e-21 75.6 0.1 3.4e-20 72.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPY50726.1 - 8.4e-15 54.7 0.0 1.5e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPY50726.1 - 3.8e-08 33.2 0.0 4.3e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EPY50726.1 - 2.7e-05 23.7 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF2048 PF09752.4 EPY50726.1 - 5e-05 22.3 0.0 0.00021 20.3 0.0 1.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2048) PAF-AH_p_II PF03403.8 EPY50726.1 - 0.0002 19.7 0.2 0.0032 15.7 0.0 2.3 3 0 0 3 3 3 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.3 EPY50726.1 - 0.00056 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 EPY50726.1 - 0.0006 19.1 0.1 0.0031 16.8 0.1 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase PF07224.6 EPY50726.1 - 0.0011 17.8 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Abhydro_lipase PF04083.11 EPY50726.1 - 0.0015 17.8 0.0 0.0034 16.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Acyl_transf_1 PF00698.16 EPY50726.1 - 0.03 13.6 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain Thioesterase PF00975.15 EPY50726.1 - 0.03 14.5 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.13 EPY50726.1 - 0.034 13.4 0.0 7.4 5.7 0.0 2.9 3 0 0 3 3 3 0 Dienelactone hydrolase family DUF915 PF06028.6 EPY50726.1 - 0.04 13.0 0.1 0.2 10.7 0.1 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.6 EPY50726.1 - 0.047 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 EPY50726.1 - 0.048 13.2 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EPY50726.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 EPY50726.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 EPY50726.1 - 0.13 11.4 0.0 0.88 8.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ribosomal_S3Ae PF01015.13 EPY50727.1 - 3e-78 261.6 5.3 3.5e-78 261.3 3.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ribosomal_S20p PF01649.13 EPY50727.1 - 0.054 13.8 0.6 0.57 10.5 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S20 DUF4168 PF13767.1 EPY50727.1 - 0.18 12.4 1.6 0.29 11.7 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Fasciclin PF02469.17 EPY50728.1 - 8.7e-30 103.3 0.5 1.5e-07 31.4 0.0 5.7 5 1 0 5 5 5 4 Fasciclin domain RNA_pol_L_2 PF13656.1 EPY50729.1 - 2.2e-32 110.3 0.0 2.9e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPY50729.1 - 9.5e-13 47.0 0.0 1.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Abi PF02517.11 EPY50730.1 - 4.7e-14 52.2 13.7 4.7e-14 52.2 9.5 2.4 2 1 0 2 2 2 1 CAAX protease self-immunity Rep_fac_C PF08542.6 EPY50731.1 - 7.3e-19 67.5 0.0 1.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPY50731.1 - 1.3e-13 50.9 0.1 2.4e-11 43.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPY50731.1 - 1.8e-11 44.3 0.1 3.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPY50731.1 - 3.9e-07 30.0 0.0 1.6e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPY50731.1 - 8.1e-06 25.0 0.0 0.00013 21.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EPY50731.1 - 2.8e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EPY50731.1 - 3e-05 22.9 0.0 0.06 12.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPY50731.1 - 3.2e-05 24.0 0.3 0.016 15.3 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPY50731.1 - 7.4e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EPY50731.1 - 9.6e-05 21.9 0.1 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EPY50731.1 - 0.00066 19.7 0.0 0.02 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EPY50731.1 - 0.00071 18.8 0.0 0.012 14.8 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EPY50731.1 - 0.0018 17.7 0.3 0.59 9.5 0.1 2.3 1 1 1 2 2 2 2 AAA-like domain AAA_11 PF13086.1 EPY50731.1 - 0.0023 17.5 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPY50731.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EPY50731.1 - 0.0053 16.4 0.4 0.084 12.5 0.1 2.3 1 1 0 2 2 2 1 NTPase AAA_18 PF13238.1 EPY50731.1 - 0.033 14.4 0.1 0.085 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain DNA_pol3_gamma3 PF12169.3 EPY50731.1 - 0.071 12.8 1.4 0.55 9.9 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III DEAD PF00270.24 EPY50731.1 - 0.11 11.9 0.1 0.99 8.8 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase IMS_HHH PF11798.3 EPY50731.1 - 0.15 12.1 0.1 16 5.8 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif Racemase_4 PF13615.1 EPY50732.1 - 7e-17 61.5 1.8 9e-17 61.2 0.3 1.9 2 0 0 2 2 2 1 Putative alanine racemase MCM_bind PF09739.4 EPY50732.1 - 1.3e-12 47.2 0.4 2.8e-12 46.2 0.3 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM PF00493.18 EPY50732.1 - 0.038 12.7 0.1 0.083 11.6 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family PINIT PF14324.1 EPY50733.1 - 1.6e-34 119.0 0.1 3.4e-34 117.9 0.1 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EPY50733.1 - 2.5e-23 81.3 5.0 4.2e-23 80.6 3.4 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EPY50733.1 - 1.5e-08 33.9 1.5 3.2e-08 32.9 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L28e PF01778.12 EPY50734.1 - 4.8e-35 120.4 0.3 5.5e-35 120.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.5 EPY50735.1 - 3.4e-37 127.0 0.4 6.9e-37 126.1 0.2 1.5 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Spb1_C PF07780.7 EPY50738.1 - 7.5e-74 247.8 25.8 7.5e-74 247.8 17.9 4.0 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 EPY50738.1 - 2.1e-53 180.9 0.0 4e-53 180.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EPY50738.1 - 1.8e-50 170.5 9.6 1.8e-50 170.5 6.6 5.3 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) Myb_DNA-bind_3 PF12776.2 EPY50738.1 - 0.0094 16.5 2.9 3.9 8.1 0.2 3.6 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Coq4 PF05019.8 EPY50739.1 - 4.3e-96 320.1 0.0 4.9e-96 319.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 JAB PF01398.16 EPY50740.1 - 9.3e-33 112.3 0.2 1.6e-32 111.6 0.2 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EPY50740.1 - 2.3e-07 30.3 0.0 3.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain EF-hand_7 PF13499.1 EPY50741.1 - 9.9e-10 38.4 0.9 1.3e-09 38.0 0.6 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EPY50741.1 - 4.9e-09 34.8 0.1 5.6e-06 25.2 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EPY50741.1 - 1.3e-07 30.8 2.1 2.4e-05 23.8 1.4 2.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EPY50741.1 - 1.9e-07 30.5 4.1 1e-05 25.0 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPY50741.1 - 3.1e-06 26.2 0.2 0.002 17.3 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 EPY50741.1 - 0.044 13.5 0.3 0.13 12.0 0.3 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 EPY50741.1 - 0.053 13.2 0.1 0.064 12.9 0.1 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB Pkinase PF00069.20 EPY50742.1 - 7.9e-64 215.2 0.0 9.4e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50742.1 - 2.1e-22 79.4 0.0 3.1e-22 78.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50742.1 - 1.3e-05 24.2 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPY50742.1 - 0.001 18.8 0.1 0.0054 16.4 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPY50742.1 - 0.009 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FA_hydroxylase PF04116.8 EPY50743.1 - 7.3e-13 48.9 20.9 7.3e-13 48.9 14.5 2.4 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily HCV_NS2 PF01538.13 EPY50743.1 - 0.036 13.5 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 DER1 PF04511.10 EPY50744.1 - 5.3e-35 120.7 13.8 6.3e-35 120.4 9.6 1.0 1 0 0 1 1 1 1 Der1-like family Cohesin_load PF10345.4 EPY50745.1 - 4.5e-76 256.3 26.8 2e-75 254.2 18.6 1.7 1 1 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.1 EPY50745.1 - 3.2e-05 23.7 2.1 4.5 7.2 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPY50745.1 - 0.012 16.2 0.1 13 6.7 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPY50745.1 - 0.05 13.5 0.2 13 5.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPY50745.1 - 0.12 12.2 1.9 4 7.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TGT PF01702.13 EPY50746.1 - 1.1e-87 293.3 0.2 1.3e-87 293.0 0.1 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CENP-I PF07778.6 EPY50747.1 - 2.6e-75 253.5 11.2 3.7e-75 253.0 7.8 1.2 1 0 0 1 1 1 1 Mis6 His_Phos_1 PF00300.17 EPY50748.1 - 2.1e-28 99.3 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 EPY50749.1 - 2.1e-28 99.3 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 EPY50750.1 - 2.1e-28 99.3 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PUF PF00806.14 EPY50751.1 - 2.4e-64 209.3 21.2 1.8e-08 33.4 0.0 8.8 8 1 1 9 9 9 8 Pumilio-family RNA binding repeat zf-Tim10_DDP PF02953.10 EPY50752.1 - 7.7e-22 76.3 0.5 8.7e-22 76.1 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EPY50752.1 - 0.049 13.0 0.4 0.086 12.3 0.3 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) YL1_C PF08265.6 EPY50754.1 - 6.2e-18 64.0 1.2 6.2e-17 60.8 0.4 2.2 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain TrmE_N PF10396.4 EPY50755.1 - 3.1e-38 130.2 0.0 1.1e-37 128.4 0.0 2.0 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EPY50755.1 - 6.8e-18 64.7 0.1 1.9e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EPY50755.1 - 8.8e-18 64.4 0.1 4.4e-17 62.2 0.0 2.3 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Dynamin_N PF00350.18 EPY50755.1 - 1.6e-07 31.2 0.4 8.1e-05 22.4 0.0 3.1 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 EPY50755.1 - 8.5e-07 28.3 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EPY50755.1 - 0.0001 21.6 0.1 0.039 13.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EPY50755.1 - 0.00015 22.1 0.0 0.00046 20.6 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EPY50755.1 - 0.00031 21.5 0.0 0.00095 19.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPY50755.1 - 0.0022 17.9 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPY50755.1 - 0.0069 16.6 0.2 0.065 13.5 0.2 2.5 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EPY50755.1 - 0.01 15.0 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPY50755.1 - 0.019 15.1 0.0 0.81 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3891 PF13030.1 EPY50755.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) AAA_18 PF13238.1 EPY50755.1 - 0.044 14.0 0.3 0.15 12.3 0.0 2.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EPY50755.1 - 0.046 13.1 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EPY50755.1 - 0.085 12.5 0.1 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EPY50755.1 - 0.15 11.5 0.0 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ribosomal_L28e PF01778.12 EPY50756.1 - 3.5e-30 104.7 0.2 3.5e-30 104.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EPY50756.1 - 1.9e-28 98.4 13.8 1.9e-28 98.4 9.6 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.13 EPY50756.1 - 0.04 13.3 0.7 0.073 12.4 0.5 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain SDA1 PF05285.7 EPY50756.1 - 0.21 10.8 20.9 0.3 10.3 14.5 1.3 1 0 0 1 1 1 0 SDA1 DUF2462 PF09495.5 EPY50756.1 - 0.91 10.3 9.5 0.23 12.2 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2462) Paf1 PF03985.8 EPY50756.1 - 2.6 6.6 19.2 4 6.0 13.3 1.2 1 0 0 1 1 1 0 Paf1 Daxx PF03344.10 EPY50756.1 - 5.7 5.2 21.6 7.9 4.8 15.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 EPY50756.1 - 6.2 6.8 18.5 13 5.7 12.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pkinase PF00069.20 EPY50757.1 - 5.1e-37 127.4 0.3 2.6e-22 79.2 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50757.1 - 2.6e-16 59.4 0.0 3.5e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase SNO PF01174.14 EPY50758.1 - 1.5e-37 129.0 0.0 3.9e-37 127.6 0.0 1.6 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPY50758.1 - 0.00018 21.1 0.0 0.00045 19.8 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EPY50758.1 - 0.0019 17.7 0.1 0.41 10.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 EPY50758.1 - 0.052 13.2 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_C26 PF07722.8 EPY50758.1 - 0.29 10.5 2.4 14 5.0 1.7 2.8 1 1 0 1 1 1 0 Peptidase C26 RRM_5 PF13893.1 EPY50759.1 - 9.7e-06 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY50759.1 - 2e-05 24.1 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50759.1 - 0.00029 20.7 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LRR_3 PF07725.7 EPY50760.1 - 2.1 8.2 7.0 2.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat Coprogen_oxidas PF01218.13 EPY50761.1 - 9.3e-124 411.7 0.2 1.1e-123 411.5 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ATP-synt_ab PF00006.20 EPY50763.1 - 2e-62 210.4 0.0 3.1e-62 209.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPY50763.1 - 1.5e-26 93.0 0.9 2.6e-26 92.3 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPY50763.1 - 1.9e-22 79.2 1.2 1.1e-21 76.7 1.1 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EPY50763.1 - 0.00088 18.7 0.0 0.062 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EPY50763.1 - 0.0037 16.4 0.2 0.0067 15.5 0.1 1.5 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 EPY50763.1 - 0.028 14.1 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EPY50763.1 - 0.035 13.7 0.2 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EPY50763.1 - 0.074 13.2 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EPY50763.1 - 0.075 12.2 0.1 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EPY50763.1 - 0.081 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EPY50763.1 - 0.092 12.7 0.2 0.54 10.2 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain NB-ARC PF00931.17 EPY50763.1 - 0.12 11.2 1.1 0.31 9.8 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain 6PF2K PF01591.13 EPY50764.1 - 6e-64 215.1 0.1 9.2e-64 214.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPY50764.1 - 2.7e-21 76.2 0.0 5.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EPY50764.1 - 1.6e-05 25.7 0.0 4.3e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY50764.1 - 0.00034 20.4 0.0 0.00084 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPY50764.1 - 0.027 14.3 0.1 0.16 11.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EPY50764.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RHD3 PF05879.7 EPY50765.1 - 3e-252 838.8 10.1 1.5e-251 836.5 7.0 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EPY50765.1 - 6.8e-07 28.6 0.2 6.8e-07 28.6 0.1 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EPY50765.1 - 1.5e-06 28.1 0.0 4.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPY50765.1 - 2.4e-05 24.2 0.6 6e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 EPY50765.1 - 0.00012 22.5 1.3 0.00084 19.8 0.1 2.8 2 1 1 3 3 3 1 Miro-like protein AAA_28 PF13521.1 EPY50765.1 - 0.033 14.1 0.1 0.075 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EPY50765.1 - 0.072 12.3 0.2 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B TBPIP PF07106.8 EPY50766.1 - 6.3e-46 156.0 5.2 8.1e-46 155.6 3.6 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EPY50766.1 - 7.6e-05 22.4 3.2 0.0001 21.9 2.2 1.4 1 0 0 1 1 1 1 Mnd1 family YjcQ PF09639.5 EPY50766.1 - 0.025 14.6 0.3 0.1 12.6 0.0 2.1 2 1 0 2 2 2 0 YjcQ protein Tropomyosin_1 PF12718.2 EPY50766.1 - 0.057 13.2 2.3 0.16 11.8 0.7 2.2 1 1 1 2 2 2 0 Tropomyosin like RseA_N PF03872.8 EPY50766.1 - 0.075 13.3 0.1 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain MethyTransf_Reg PF10119.4 EPY50766.1 - 0.076 13.5 0.0 0.47 10.9 0.0 2.2 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain Mod_r PF07200.8 EPY50766.1 - 0.42 10.5 6.0 0.91 9.4 0.4 2.8 1 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 EPY50766.1 - 1.8 8.0 5.6 4.4 6.8 3.8 1.7 1 1 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EPY50766.1 - 2.1 8.3 9.7 0.52 10.3 0.9 3.0 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PCI_Csn8 PF10075.4 EPY50767.1 - 0.057 13.1 0.4 9.7 5.9 0.0 2.3 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 PAP_assoc PF03828.14 EPY50769.1 - 1.6e-16 59.9 0.4 4.4e-16 58.5 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPY50769.1 - 1.5e-06 28.4 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain OAS1_C PF10421.4 EPY50769.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus JAB PF01398.16 EPY50770.1 - 1.9e-06 27.5 0.0 4.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Dec-1 PF04624.9 EPY50770.1 - 0.21 11.2 4.4 0.44 10.2 3.1 1.4 1 0 0 1 1 1 0 Dec-1 repeat Septin PF00735.13 EPY50771.1 - 1.1e-111 372.3 0.2 1.3e-111 372.1 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPY50771.1 - 1.1e-09 38.1 0.0 5.7e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPY50771.1 - 3e-06 26.7 0.1 6.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPY50771.1 - 4.7e-06 25.8 0.0 7.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPY50771.1 - 2.2e-05 24.5 0.0 3.8e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EPY50771.1 - 2.6e-05 23.7 0.2 4.4e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EPY50771.1 - 2.8e-05 24.4 0.2 5.1e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 EPY50771.1 - 5.1e-05 23.1 1.5 0.043 13.6 0.3 2.4 1 1 1 2 2 2 2 Dynamin family AAA_29 PF13555.1 EPY50771.1 - 6.8e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.11 EPY50771.1 - 8.4e-05 21.7 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 AIG1 family T2SE PF00437.15 EPY50771.1 - 8.5e-05 21.5 0.0 0.00017 20.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EPY50771.1 - 0.00015 21.6 0.0 0.00044 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EPY50771.1 - 0.00022 20.7 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EPY50771.1 - 0.00024 21.9 0.4 0.0024 18.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EPY50771.1 - 0.00034 19.8 0.1 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EPY50771.1 - 0.00049 19.9 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EPY50771.1 - 0.0012 19.3 0.0 0.0038 17.7 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EPY50771.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain GBP PF02263.14 EPY50771.1 - 0.0019 17.2 0.0 0.0042 16.1 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MobB PF03205.9 EPY50771.1 - 0.0047 16.6 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EPY50771.1 - 0.0055 17.0 0.0 0.0065 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPY50771.1 - 0.0084 16.0 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EPY50771.1 - 0.0094 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase SRPRB PF09439.5 EPY50771.1 - 0.011 14.9 0.3 0.033 13.3 0.0 1.9 3 0 0 3 3 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EPY50771.1 - 0.012 15.1 0.1 0.063 12.8 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 EPY50771.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 EPY50771.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPY50771.1 - 0.017 15.4 0.4 0.098 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 EPY50771.1 - 0.02 14.3 0.0 0.076 12.4 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase PduV-EutP PF10662.4 EPY50771.1 - 0.028 13.9 0.1 0.18 11.2 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EPY50771.1 - 0.048 13.3 0.0 0.14 11.7 0.0 1.9 3 0 0 3 3 1 0 Archaeal ATPase AAA_24 PF13479.1 EPY50771.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain IIGP PF05049.8 EPY50771.1 - 0.054 12.3 0.1 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.7 EPY50771.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Adeno_IVa2 PF02456.10 EPY50771.1 - 0.056 12.0 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein cobW PF02492.14 EPY50771.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EPY50771.1 - 0.064 12.4 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ras PF00071.17 EPY50771.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Ras family Sigma54_activat PF00158.21 EPY50771.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EPY50771.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zn_clus PF00172.13 EPY50772.1 - 3.6e-09 36.3 10.4 7.3e-09 35.3 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EPY50773.1 - 1.1e-25 88.5 9.8 4.3e-08 32.7 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EPY50773.1 - 6.5e-08 32.5 4.0 0.0004 20.1 0.2 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EPY50773.1 - 0.00057 19.6 3.5 0.97 9.1 0.1 3.5 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term Glyco_hydro_81 PF03639.8 EPY50774.1 - 1.8e-186 621.2 17.6 3e-186 620.4 12.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Carb_bind PF10645.4 EPY50774.1 - 4e-54 180.1 45.8 1.3e-22 79.3 8.3 3.4 3 0 0 3 3 3 3 Carbohydrate binding DUF3746 PF12562.3 EPY50774.1 - 0.2 11.4 6.6 0.37 10.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) IGFL PF14653.1 EPY50774.1 - 3.6 7.6 21.7 5.5 7.0 0.2 5.1 3 2 1 5 5 5 0 Insulin growth factor-like family Sod_Cu PF00080.15 EPY50775.1 - 1.6e-45 154.7 6.4 1.8e-45 154.5 4.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Staphylcoagulse PF04022.7 EPY50775.1 - 8.4 5.8 6.4 1 8.7 0.5 2.4 3 0 0 3 3 3 0 Staphylocoagulase repeat Aldedh PF00171.17 EPY50776.1 - 1.2e-21 76.6 0.3 2.1e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Pkinase PF00069.20 EPY50777.1 - 3.5e-57 193.5 0.0 1e-37 129.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50777.1 - 2.3e-27 95.7 0.0 2.1e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EPY50777.1 - 0.0002 20.5 0.1 0.00061 18.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY50777.1 - 0.00027 20.0 0.0 0.00051 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPY50777.1 - 0.005 16.5 0.5 0.061 13.0 0.3 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EPY50777.1 - 0.012 16.0 0.1 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EPY50777.1 - 0.043 12.6 0.1 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EPY50777.1 - 0.052 12.3 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase E1-E2_ATPase PF00122.15 EPY50778.1 - 1.9e-20 72.9 2.5 2e-19 69.5 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPY50778.1 - 6e-13 49.7 0.1 5.8e-11 43.2 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPY50778.1 - 2.1e-12 47.6 0.0 9.9e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY50778.1 - 3.1e-12 46.2 0.0 1.4e-11 44.2 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPY50778.1 - 0.00027 20.5 0.2 0.001 18.6 0.1 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FlgN PF05130.7 EPY50778.1 - 0.1 12.8 0.6 0.49 10.6 0.2 2.0 2 0 0 2 2 2 0 FlgN protein MKT1_C PF12246.3 EPY50779.1 - 1.5e-22 79.7 1.8 2.3e-22 79.1 1.2 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EPY50779.1 - 1e-14 54.5 0.0 4.6e-12 46.0 0.0 2.7 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EPY50779.1 - 4.8e-10 39.3 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPY50779.1 - 2.9e-09 37.0 0.0 7.3e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain Mito_carr PF00153.22 EPY50780.1 - 5e-54 179.9 4.4 1e-17 63.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EPY50781.1 - 1.4e-24 86.4 0.4 1.4e-24 86.4 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY50781.1 - 7.8e-09 35.3 10.7 1.3e-08 34.6 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EPY50782.1 - 1.7e-47 162.0 0.0 2e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPY50782.1 - 0.00032 20.6 0.0 0.68 9.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPY50782.1 - 0.00062 19.8 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPY50782.1 - 0.004 17.1 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPY50782.1 - 0.0075 15.1 0.2 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EPY50782.1 - 0.023 14.4 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.16 EPY50782.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.14 EPY50782.1 - 0.19 10.7 0.0 0.48 9.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Aldedh PF00171.17 EPY50783.1 - 1.3e-157 524.8 0.1 1.5e-157 524.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hat1_N PF10394.4 EPY50784.1 - 5.4e-20 72.0 1.1 1.2e-18 67.6 0.8 2.3 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EPY50784.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain VPS9 PF02204.13 EPY50784.1 - 0.11 12.5 1.3 0.32 11.0 0.2 2.2 3 0 0 3 3 3 0 Vacuolar sorting protein 9 (VPS9) domain DUF1900 PF08954.6 EPY50785.1 - 7.7e-51 171.1 0.0 2.7e-50 169.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EPY50785.1 - 2.4e-31 107.1 0.0 4.3e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EPY50785.1 - 3.7e-26 90.0 3.3 1.3e-08 34.3 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF3635 PF12330.3 EPY50786.1 - 2.8e-23 81.8 0.2 9.5e-23 80.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Ish1 PF10281.4 EPY50788.1 - 5.6e-29 99.8 15.3 4.7e-12 45.7 0.0 6.8 6 1 0 6 6 6 5 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EPY50788.1 - 0.00083 18.7 0.0 1.6 8.3 0.0 3.7 3 1 0 3 3 3 2 SAP domain SAM_2 PF07647.12 EPY50788.1 - 0.038 13.8 3.2 5.7 6.8 0.0 4.1 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Methyltransf_16 PF10294.4 EPY50789.1 - 1.1e-47 161.7 0.2 1.5e-47 161.3 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EPY50789.1 - 4.5e-07 29.3 0.0 7.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EPY50789.1 - 8.9e-05 23.0 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY50789.1 - 9.4e-05 22.8 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY50789.1 - 0.00061 19.4 0.1 0.00094 18.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EPY50789.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.8 EPY50789.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 EPY50789.1 - 0.062 12.8 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUSP PF06337.7 EPY50789.1 - 0.077 13.4 0.1 0.51 10.7 0.0 2.1 2 0 0 2 2 2 0 DUSP domain Ras PF00071.17 EPY50791.1 - 3.1e-54 182.7 0.0 3.6e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY50791.1 - 1.9e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY50791.1 - 1.7e-09 37.1 0.0 2.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY50791.1 - 0.00046 19.4 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPY50791.1 - 0.0032 17.4 0.0 0.0058 16.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPY50791.1 - 0.0057 15.8 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPY50791.1 - 0.028 13.8 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EPY50791.1 - 0.1 12.9 0.0 0.21 11.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter dsDNA_bind PF01984.15 EPY50792.1 - 3.8e-31 107.2 11.4 4.4e-31 107.0 7.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain SDA1 PF05285.7 EPY50792.1 - 0.78 8.9 8.2 0.097 11.9 1.7 1.8 2 0 0 2 2 2 0 SDA1 Sec2p PF06428.6 EPY50793.1 - 2.2e-25 88.4 5.7 2.2e-25 88.4 3.9 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF745 PF05335.8 EPY50793.1 - 0.00047 19.7 5.1 0.001 18.6 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF745) AATF-Che1 PF13339.1 EPY50793.1 - 0.0074 16.4 0.6 0.0074 16.4 0.4 2.7 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor IncA PF04156.9 EPY50793.1 - 0.12 11.9 20.7 0.2 11.2 14.4 1.4 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EPY50793.1 - 0.17 12.2 10.2 0.058 13.7 1.1 3.3 1 1 1 2 2 2 0 SlyX HSP70 PF00012.15 EPY50793.1 - 1.2 6.9 9.2 1.9 6.3 6.4 1.2 1 0 0 1 1 1 0 Hsp70 protein ATP-synt_J PF04911.7 EPY50794.1 - 1.7e-14 52.9 0.1 2e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 ATP synthase j chain Pkinase PF00069.20 EPY50795.1 - 1.5e-39 135.7 0.0 1.9e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50795.1 - 8.3e-16 57.8 0.0 9.7e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY50795.1 - 2e-05 24.4 0.0 0.00064 19.5 0.0 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPY50795.1 - 0.0075 15.1 0.5 0.011 14.5 0.3 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EPY50795.1 - 0.038 13.5 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EPY50795.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SNARE PF05739.14 EPY50796.1 - 4.2e-09 35.9 0.1 5.7e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EPY50796.1 - 0.00011 21.7 0.0 0.00014 21.4 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.8 EPY50796.1 - 0.01 15.5 0.2 0.014 15.1 0.1 1.3 1 0 0 1 1 1 0 Sec20 YycI PF09648.5 EPY50796.1 - 0.023 14.1 0.0 0.027 13.9 0.0 1.0 1 0 0 1 1 1 0 YycH protein Corona_S2 PF01601.11 EPY50796.1 - 0.076 11.1 0.1 0.083 10.9 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Syntaxin_2 PF14523.1 EPY50796.1 - 0.12 12.3 0.5 0.16 11.9 0.3 1.1 1 0 0 1 1 1 0 Syntaxin-like protein Glyco_trans_1_4 PF13692.1 EPY50797.1 - 1.2e-20 74.0 0.0 2.4e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EPY50797.1 - 9.8e-10 38.1 0.0 2.9e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EPY50797.1 - 2.2e-07 31.0 0.0 4.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPY50797.1 - 6.3e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Hydrolase_4 PF12146.3 EPY50797.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase RNA_pol_Rpb5_C PF01191.14 EPY50798.1 - 4.3e-35 119.1 0.6 3.3e-34 116.3 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EPY50798.1 - 4.7e-27 94.2 0.0 7.6e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EPY50798.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease DUF4480 PF13715.1 EPY50798.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) Lipase_3 PF01764.20 EPY50799.1 - 1.2e-08 34.6 0.1 4.1e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Coat_F PF07875.7 EPY50799.1 - 0.011 15.8 0.3 5.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Coat F domain Abhydrolase_5 PF12695.2 EPY50799.1 - 0.042 13.6 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nol1_Nop2_Fmu PF01189.12 EPY50800.1 - 1.2e-33 116.7 0.0 1.8e-20 73.5 0.0 3.9 1 1 1 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EPY50800.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PTCB-BRCT PF12738.2 EPY50801.1 - 6.9e-40 134.7 4.3 8.8e-19 67.1 0.0 4.5 4 1 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EPY50801.1 - 6.2e-38 128.8 2.9 1.1e-12 47.9 0.0 4.6 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain CTD PF12815.2 EPY50802.1 - 6.7e-34 116.9 53.4 1.9e-21 76.7 21.8 2.5 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EPY50802.1 - 1.1e-27 95.5 0.1 2.1e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EPY50802.1 - 2.8e-16 59.9 12.3 2.8e-16 59.9 8.5 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EPY50802.1 - 7.9e-14 50.7 22.4 1.2e-07 31.1 0.4 5.2 5 0 0 5 5 5 3 KOW motif zf-C2HC5 PF06221.8 EPY50803.1 - 3.6e-22 77.8 6.8 6.5e-22 77.0 4.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PH_BEACH PF14844.1 EPY50803.1 - 0.021 14.6 0.7 0.071 12.9 0.0 2.3 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH DUF2870 PF11069.3 EPY50803.1 - 0.72 9.9 0.1 0.72 9.9 0.0 4.2 4 2 1 5 5 5 0 Protein of unknown function (DUF2870) HSA PF07529.8 EPY50803.1 - 0.88 9.3 6.9 0.23 11.2 0.7 2.9 3 0 0 3 3 3 0 HSA WD40 PF00400.27 EPY50804.1 - 8.4e-05 22.2 10.6 0.032 14.1 0.3 5.1 4 1 1 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.1 EPY50804.1 - 0.00028 21.0 2.3 8.9 6.7 0.1 4.0 4 0 0 4 4 4 2 PQQ-like domain SDA1 PF05285.7 EPY50804.1 - 0.37 10.0 10.0 0.65 9.2 6.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EPY50804.1 - 0.7 7.7 10.8 0.99 7.2 7.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EPY50804.1 - 0.87 7.5 9.7 1.2 7.0 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EPY50804.1 - 0.98 8.9 6.4 2.3 7.7 4.5 1.7 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EPY50804.1 - 4.6 6.3 9.1 3.5 6.7 5.0 1.7 2 0 0 2 2 2 0 NOA36 protein PLA2_B PF01735.13 EPY50805.1 - 5.8e-200 664.6 4.6 7.3e-200 664.2 3.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 EPY50806.1 - 2.3e-177 590.0 8.0 2.9e-177 589.7 5.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3336 PF11815.3 EPY50807.1 - 9.2e-39 132.2 1.5 1.4e-38 131.6 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPY50807.1 - 3.2e-20 72.9 0.0 5.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.12 EPY50807.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 DUF572 PF04502.8 EPY50810.1 - 0.022 13.9 0.9 0.051 12.7 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF572) DUF2072 PF09845.4 EPY50810.1 - 0.038 13.9 0.1 0.36 10.7 0.2 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) TRAM_LAG1_CLN8 PF03798.11 EPY50811.1 - 1.1e-35 123.0 31.0 1.1e-35 123.0 21.5 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPY50811.1 - 3.9e-18 64.7 2.1 8e-18 63.6 0.5 2.3 2 0 0 2 2 2 1 TRAM1-like protein Multi_Drug_Res PF00893.14 EPY50811.1 - 0.076 13.4 3.6 0.21 12.0 1.1 2.4 2 0 0 2 2 2 0 Small Multidrug Resistance protein ThiF PF00899.16 EPY50812.1 - 1.3e-37 128.6 0.0 2.4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EPY50812.1 - 7.7e-05 21.8 0.0 0.00019 20.5 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase MRJP PF03022.11 EPY50812.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Major royal jelly protein ApbA PF02558.11 EPY50812.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EPY50812.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 EPY50812.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EPY50812.1 - 0.1 11.4 0.1 0.3 9.9 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase KH_3 PF13014.1 EPY50813.1 - 2e-06 27.2 0.1 0.0004 19.9 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_1 PF00013.24 EPY50813.1 - 3.8e-06 26.4 0.0 9.4e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 KH domain Sporozoite_P67 PF05642.6 EPY50813.1 - 0.013 13.4 0.1 0.019 12.8 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen UQ_con PF00179.21 EPY50814.1 - 4.5e-47 159.0 0.0 5.1e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPY50814.1 - 0.00094 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPY50814.1 - 0.05 13.4 0.9 0.07 13.0 0.6 1.7 1 1 0 1 1 1 0 RWD domain Ribosomal_L38e PF01781.13 EPY50815.1 - 7e-33 112.1 0.9 7.8e-33 112.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Alpha-mann_mid PF09261.6 EPY50815.1 - 0.048 13.8 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Alpha mannosidase, middle domain HlyIII PF03006.15 EPY50816.1 - 1.3e-54 184.9 28.2 1.7e-54 184.6 19.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.3 EPY50816.1 - 1.7 8.5 4.4 1 9.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) Rad52_Rad22 PF04098.10 EPY50817.1 - 6.6e-60 201.3 0.0 1.1e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MTHFR PF02219.12 EPY50818.1 - 1e-123 412.0 0.0 1.5e-123 411.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Radical_SAM PF04055.16 EPY50818.1 - 0.09 12.9 0.0 0.82 9.8 0.0 2.6 2 1 0 2 2 2 0 Radical SAM superfamily Methyltransf_8 PF05148.10 EPY50819.1 - 2.9e-87 291.9 0.0 3.6e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EPY50819.1 - 2.3e-09 37.6 0.0 6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY50819.1 - 0.00013 21.5 0.1 0.017 14.7 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY50819.1 - 0.00033 20.3 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPY50819.1 - 0.0064 15.6 0.0 0.12 11.4 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPY50819.1 - 0.017 15.4 0.1 0.26 11.6 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EPY50819.1 - 0.061 13.7 0.0 0.81 10.2 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Asp_protease PF09668.5 EPY50820.1 - 5.2e-60 200.4 0.1 9.6e-60 199.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF2781 PF10914.3 EPY50820.1 - 9.6e-27 93.6 13.0 1.4e-26 93.0 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Asp_protease_2 PF13650.1 EPY50820.1 - 1.2e-11 44.8 0.0 2.7e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EPY50820.1 - 4.1e-08 32.9 0.5 1.6e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 EPY50820.1 - 5.3e-07 29.2 0.0 1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 EPY50820.1 - 3.6e-05 23.7 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EPY50820.1 - 0.00016 21.5 0.0 0.00059 19.7 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EPY50820.1 - 0.089 12.3 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DIE2_ALG10 PF04922.7 EPY50821.1 - 3.1e-102 342.4 34.5 3.8e-102 342.1 23.9 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family UbiA PF01040.13 EPY50822.1 - 2.3e-34 118.7 11.2 2.8e-34 118.4 7.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GTP_EFTU PF00009.22 EPY50823.1 - 1e-32 113.0 0.0 8.2e-32 110.1 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPY50823.1 - 3.1e-18 65.6 0.0 8.1e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPY50823.1 - 1.2e-14 54.1 5.8 4.9e-09 36.1 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPY50823.1 - 6.5e-07 29.3 0.1 4.7e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EPY50823.1 - 0.0064 16.1 0.4 0.022 14.4 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_22 PF13401.1 EPY50823.1 - 0.0096 16.0 0.0 0.048 13.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY50823.1 - 0.15 12.0 2.9 0.32 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain SpecificRecomb PF10136.4 EPY50823.1 - 0.18 9.8 0.9 0.21 9.5 0.0 1.5 2 0 0 2 2 2 0 Site-specific recombinase Miro PF08477.8 EPY50823.1 - 0.38 11.2 0.0 0.38 11.2 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AMP-binding PF00501.23 EPY50824.1 - 4.7e-48 163.6 0.0 3.7e-17 61.8 0.0 4.2 4 1 0 4 4 4 4 AMP-binding enzyme DEAD PF00270.24 EPY50825.1 - 1e-42 145.5 0.1 2e-42 144.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY50825.1 - 2.4e-25 88.1 0.0 6.4e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Solute_trans_a PF03619.11 EPY50827.1 - 6.5e-85 284.7 10.3 7.9e-85 284.4 7.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Clat_adaptor_s PF01217.15 EPY50828.1 - 5.6e-54 181.7 0.7 6.6e-54 181.4 0.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HhH-GPD PF00730.20 EPY50829.1 - 1.7e-16 60.4 0.0 3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPY50829.1 - 1.2e-08 34.2 0.0 2.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EPY50829.1 - 0.02 15.0 0.0 0.64 10.2 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain MRP-S26 PF14943.1 EPY50829.1 - 0.065 12.7 2.8 0.12 11.9 1.9 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PHD PF00628.24 EPY50830.1 - 4.5e-10 39.0 8.1 7.9e-10 38.2 5.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPY50830.1 - 0.0074 15.5 3.8 0.036 13.3 2.7 2.1 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EPY50830.1 - 0.021 14.5 1.7 0.021 14.5 1.2 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EPY50830.1 - 0.094 12.4 6.5 0.027 14.1 2.1 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Neuropep_like PF15161.1 EPY50830.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide-like zf-PHD-like PF15446.1 EPY50830.1 - 0.26 10.5 3.1 0.32 10.2 1.1 1.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain CwfJ_C_1 PF04677.10 EPY50831.1 - 2.3e-38 130.6 0.0 3.6e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPY50831.1 - 2.8e-20 72.6 0.1 2.8e-20 72.6 0.1 2.8 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 SPC22 PF04573.7 EPY50832.1 - 2.7e-45 153.7 2.1 3e-45 153.5 1.5 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF2434 PF10361.4 EPY50833.1 - 4.3e-57 193.4 0.4 5.9e-57 192.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF4131 PF13567.1 EPY50833.1 - 0.016 14.6 8.1 0.28 10.5 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) HLH PF00010.21 EPY50834.1 - 8.6e-15 54.1 2.5 1.6e-14 53.2 1.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DRMBL PF07522.9 EPY50835.1 - 3.2e-26 91.5 0.0 6.6e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EPY50835.1 - 1.6e-10 40.8 0.2 2.9e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPY50835.1 - 7.6e-05 22.4 1.9 0.00015 21.4 1.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Clp1 PF06807.9 EPY50835.1 - 0.014 15.1 0.0 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 Ion_trans_N PF08412.5 EPY50835.1 - 0.057 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal EDR1 PF14381.1 EPY50836.1 - 0.022 14.3 0.2 0.032 13.8 0.0 1.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 PCI PF01399.22 EPY50837.1 - 3.2e-08 33.8 0.6 1.1e-07 32.1 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EPY50837.1 - 0.065 13.1 2.1 0.43 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50837.1 - 0.12 12.3 4.3 0.096 12.6 0.5 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPY50837.1 - 0.2 11.3 4.6 0.13 11.9 0.6 2.5 1 1 1 2 2 2 0 TPR repeat TPR_1 PF00515.23 EPY50837.1 - 0.7 9.5 3.6 3.7 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S8 PF00410.14 EPY50838.1 - 5e-27 94.2 0.2 6.7e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 TFIIS_C PF01096.13 EPY50839.1 - 5.9e-20 70.6 15.1 3.1e-19 68.3 2.8 3.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPY50839.1 - 5.2e-15 54.8 0.4 5.2e-15 54.8 0.3 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EPY50839.1 - 3.7e-05 23.4 6.9 0.012 15.4 0.4 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DZR PF12773.2 EPY50839.1 - 0.011 15.5 0.4 0.011 15.5 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-C4_Topoisom PF01396.14 EPY50839.1 - 0.03 13.8 2.9 0.2 11.1 0.0 3.1 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Baculo_LEF5_C PF11792.3 EPY50839.1 - 0.052 12.9 0.3 0.052 12.9 0.2 2.3 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DNA_ligase_ZBD PF03119.11 EPY50839.1 - 0.12 12.0 0.1 0.12 12.0 0.0 2.9 4 0 0 4 4 3 0 NAD-dependent DNA ligase C4 zinc finger domain C1_1 PF00130.17 EPY50839.1 - 0.17 11.6 7.4 0.19 11.4 0.4 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 EPY50839.1 - 0.17 11.5 4.6 0.27 10.9 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like C1_4 PF07975.7 EPY50839.1 - 0.18 11.8 9.6 2.9 7.9 0.2 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_2 PF13240.1 EPY50839.1 - 0.23 10.9 0.3 0.23 10.9 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EPY50839.1 - 0.4 10.0 5.5 6.1 6.2 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 EPY50839.1 - 0.47 10.1 5.6 1.5 8.5 0.2 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain C1_3 PF07649.7 EPY50839.1 - 0.54 10.3 0.2 0.54 10.3 0.1 3.0 3 0 0 3 3 3 0 C1-like domain zf-TFIIB PF13453.1 EPY50839.1 - 0.66 9.2 3.0 2.1 7.6 0.7 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger PhnA_Zn_Ribbon PF08274.7 EPY50839.1 - 0.67 9.7 4.2 18 5.2 0.1 3.2 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Nudix_N_2 PF14803.1 EPY50839.1 - 1 9.1 6.9 0.38 10.4 1.3 2.4 2 1 0 2 2 2 0 Nudix N-terminal zf-Mss51 PF13824.1 EPY50839.1 - 1.2 9.0 4.4 0.7 9.7 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PHD PF00628.24 EPY50839.1 - 1.8 8.3 8.5 7.3 6.3 1.8 2.6 2 1 0 2 2 2 0 PHD-finger NOB1_Zn_bind PF08772.6 EPY50839.1 - 2.7 7.8 5.8 1.6 8.6 1.6 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like IBR PF01485.16 EPY50839.1 - 5.4 6.9 11.7 4.9 7.0 0.5 2.6 2 1 0 2 2 2 0 IBR domain FSH1 PF03959.8 EPY50840.1 - 6.6e-36 123.7 0.0 1.8e-35 122.3 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPY50840.1 - 2.4e-05 24.0 0.0 7.7e-05 22.4 0.0 1.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family DLH PF01738.13 EPY50840.1 - 0.0046 16.2 0.0 0.11 11.7 0.0 2.5 2 1 1 3 3 3 1 Dienelactone hydrolase family PMT PF02366.13 EPY50841.1 - 1.4e-59 201.4 20.1 1.4e-59 201.4 13.9 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPY50841.1 - 9.6e-39 132.8 0.0 1.4e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 MIR domain Hydrolase_like PF13242.1 EPY50842.1 - 3.5e-22 77.9 0.1 1.9e-21 75.5 0.0 2.3 3 1 1 4 4 4 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EPY50842.1 - 6.5e-19 67.7 0.0 1.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CDP-OH_P_transf PF01066.16 EPY50842.1 - 3e-17 62.7 4.5 5.4e-17 61.9 3.1 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase HAD_2 PF13419.1 EPY50842.1 - 1.5e-05 25.3 0.1 0.0087 16.3 0.0 3.6 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY50842.1 - 0.0069 16.8 0.0 3.5 7.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PRP21_like_P PF12230.3 EPY50843.1 - 3e-60 203.5 3.1 5.8e-60 202.6 2.1 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EPY50843.1 - 1.5e-36 123.8 2.6 1.7e-20 72.4 0.2 2.3 2 0 0 2 2 2 2 Surp module CDP-OH_P_transf PF01066.16 EPY50844.1 - 1.8e-15 57.0 4.3 1.8e-15 57.0 3.0 2.7 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Dak1 PF02733.12 EPY50845.1 - 2.1e-138 460.3 1.7 2.9e-138 459.8 1.2 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EPY50845.1 - 8.4e-47 159.0 1.3 1.6e-46 158.1 0.9 1.5 1 0 0 1 1 1 1 DAK2 domain BSD PF03909.12 EPY50847.1 - 9.7e-15 54.0 0.9 2.8e-14 52.5 0.6 1.9 1 0 0 1 1 1 1 BSD domain PIG-P PF08510.7 EPY50848.1 - 7.6e-30 103.1 7.1 2.5e-29 101.4 5.0 1.8 1 1 0 1 1 1 1 PIG-P Cas1_AcylT PF07779.7 EPY50848.1 - 0.0083 14.6 0.6 0.01 14.3 0.4 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DPM2 PF07297.7 EPY50848.1 - 0.24 11.7 7.5 0.36 11.1 5.2 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF485 PF04341.7 EPY50848.1 - 1.8 8.3 6.5 0.26 11.0 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Adipogenin PF15202.1 EPY50848.1 - 2.8 7.8 9.8 4 7.3 1.7 2.4 1 1 1 2 2 2 0 Adipogenin HSP70 PF00012.15 EPY50849.1 - 1.2e-263 875.5 11.2 1.3e-263 875.4 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPY50849.1 - 1.5e-20 73.1 0.3 4.4e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EPY50849.1 - 0.00014 21.1 3.0 0.009 15.1 0.2 3.1 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase FtsA PF14450.1 EPY50849.1 - 0.64 9.8 7.7 0.59 9.9 0.2 3.4 2 1 0 2 2 2 0 Cell division protein FtsA ATP-grasp_2 PF08442.5 EPY50850.1 - 1.4e-09 37.6 0.0 2.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain adh_short PF00106.20 EPY50851.1 - 5.1e-32 111.0 0.3 6.2e-32 110.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY50851.1 - 6e-31 108.0 0.1 7.3e-31 107.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY50851.1 - 2e-16 60.1 0.1 2.7e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPY50851.1 - 0.0099 15.6 0.2 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPY50851.1 - 0.019 14.4 0.8 0.041 13.2 0.5 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family IcmL PF11393.3 EPY50851.1 - 0.026 14.4 0.0 0.68 9.8 0.0 2.4 2 1 0 2 2 2 0 Macrophage killing protein with similarity to conjugation protein Spore_IV_A PF09547.5 EPY50851.1 - 0.041 12.5 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) HGD-D PF06050.8 EPY50851.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Peptidase_C58 PF03543.9 EPY50851.1 - 0.12 11.8 0.5 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen RmlD_sub_bind PF04321.12 EPY50851.1 - 0.12 11.2 1.8 6.1 5.6 0.0 2.2 1 1 1 2 2 2 0 RmlD substrate binding domain RVT_1 PF00078.22 EPY50852.1 - 3e-20 72.5 0.2 9.4e-20 70.8 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAD_2 PF13419.1 EPY50853.1 - 1.1e-16 61.5 0.0 1.4e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY50853.1 - 4.4e-13 50.1 0.0 2.7e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPY50853.1 - 1.6e-05 24.5 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EPY50853.1 - 0.00025 20.8 0.0 0.071 13.0 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPY50853.1 - 0.13 11.9 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 Acid Phosphatase Ras PF00071.17 EPY50854.1 - 5.8e-60 201.3 0.5 7.5e-60 200.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY50854.1 - 1.6e-20 73.7 0.0 3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY50854.1 - 2e-16 59.7 0.5 2.5e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPY50854.1 - 1.9e-07 30.6 0.1 8.6e-07 28.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPY50854.1 - 7.9e-07 28.4 0.9 9.8e-07 28.1 0.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPY50854.1 - 1.8e-06 27.3 0.1 2.7e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPY50854.1 - 1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPY50854.1 - 0.01 15.9 0.1 0.31 11.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.18 EPY50854.1 - 0.01 15.6 0.5 1.9 8.2 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EPY50854.1 - 0.019 14.6 0.1 0.055 13.1 0.0 1.6 1 1 1 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EPY50854.1 - 0.07 12.6 1.3 0.35 10.3 0.5 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PQ-loop PF04193.9 EPY50855.1 - 4.1e-11 42.2 17.4 2.6e-09 36.4 0.5 3.1 3 0 0 3 3 3 2 PQ loop repeat MadM PF03818.8 EPY50855.1 - 0.0092 15.5 1.1 0.053 13.1 0.7 2.3 1 0 0 1 1 1 1 Malonate/sodium symporter MadM subunit PgaD PF13994.1 EPY50855.1 - 0.78 9.2 4.9 1.6 8.1 0.8 2.9 3 0 0 3 3 3 0 PgaD-like protein DUF2681 PF10883.3 EPY50855.1 - 9.9 6.4 6.1 0.8 9.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ThiF PF00899.16 EPY50856.1 - 4.1e-15 55.7 0.0 7.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family NIR_SIR PF01077.17 EPY50857.1 - 4.2e-46 156.1 0.0 4.8e-43 146.2 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 EPY50857.1 - 1.7e-30 105.9 0.0 3.4e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.12 EPY50857.1 - 9.8e-29 98.7 0.0 1.3e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain OB_NTP_bind PF07717.11 EPY50858.1 - 1.8e-27 95.4 0.0 4.2e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPY50858.1 - 1.9e-27 95.2 0.1 4.7e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) S1 PF00575.18 EPY50858.1 - 2.7e-14 53.0 0.1 5.7e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 EPY50858.1 - 4.2e-11 42.5 0.0 1.2e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY50858.1 - 1.4e-08 34.4 0.2 3.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPY50858.1 - 9.2e-06 25.8 0.1 3.1e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPY50858.1 - 0.0016 18.7 8.3 0.016 15.5 0.2 3.7 3 1 0 3 3 3 1 ABC transporter AAA_30 PF13604.1 EPY50858.1 - 0.0017 18.0 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EPY50858.1 - 0.0025 16.7 0.1 0.01 14.7 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 EPY50858.1 - 0.0033 17.3 0.1 0.062 13.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPY50858.1 - 0.0059 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EPY50858.1 - 0.023 14.4 0.1 0.071 12.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 EPY50858.1 - 0.028 14.1 0.2 0.092 12.5 0.1 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain CTP_synth_N PF06418.9 EPY50859.1 - 2.6e-118 394.0 0.5 3.6e-118 393.6 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EPY50859.1 - 4.8e-55 186.0 0.0 7.5e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPY50859.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EPY50859.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UQ_con PF00179.21 EPY50860.1 - 3.2e-27 94.6 0.8 3.8e-27 94.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPY50860.1 - 0.063 13.1 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 RWD domain CcmE PF03100.10 EPY50860.1 - 0.12 11.9 0.1 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 CcmE DUF2077 PF09850.4 EPY50860.1 - 0.18 11.1 0.5 0.32 10.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Ctr PF04145.10 EPY50860.1 - 1.2 9.2 6.0 5.5 7.0 1.0 2.4 2 1 0 2 2 2 0 Ctr copper transporter family RCC1 PF00415.13 EPY50861.1 - 7e-27 93.4 10.2 8.9e-11 41.8 0.0 7.4 6 3 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPY50861.1 - 5.3e-12 45.0 27.6 2.4e-07 30.1 0.1 6.9 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Reg_prop PF07494.6 EPY50861.1 - 0.69 10.1 10.0 3.9 7.8 0.1 4.4 4 0 0 4 4 4 0 Two component regulator propeller RRM_6 PF14259.1 EPY50862.1 - 8.1e-08 32.1 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY50862.1 - 4.2e-07 29.5 0.0 7.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 EPY50863.1 - 1.6e-11 44.3 2.9 1.6e-11 44.3 2.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPY50863.1 - 6.4e-05 23.2 2.9 6.4e-05 23.2 2.0 2.8 3 0 0 3 3 3 1 HMG-box domain PRA-CH PF01502.13 EPY50863.1 - 0.14 11.8 0.1 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase SMC_N PF02463.14 EPY50864.1 - 3.3e-56 189.9 51.5 2.6e-31 108.5 12.4 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPY50864.1 - 4.1e-31 107.4 0.0 1.5e-30 105.6 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPY50864.1 - 4.5e-11 43.2 21.6 1.6e-06 28.3 0.0 4.5 2 2 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EPY50864.1 - 1.4e-07 32.0 115.8 2.9e-07 31.0 35.3 6.8 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EPY50864.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_TATA_bd PF12325.3 EPY50864.1 - 0.0068 16.1 5.3 0.0068 16.1 3.6 8.8 5 2 3 9 9 9 1 TATA element modulatory factor 1 TATA binding FtsK_SpoIIIE PF01580.13 EPY50864.1 - 0.18 11.2 0.0 0.18 11.2 0.0 2.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family RIO1 PF01163.17 EPY50865.1 - 8.1e-75 250.3 0.2 8.1e-75 250.3 0.2 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EPY50865.1 - 0.0015 18.3 0.0 0.048 13.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family APG17 PF04108.7 EPY50866.1 - 1.3e-76 258.0 17.3 5.2e-76 256.0 12.0 1.8 1 1 0 1 1 1 1 Autophagy protein Apg17 TLE_N PF03920.10 EPY50866.1 - 6.3e-05 22.8 3.3 6.3e-05 22.8 2.3 1.9 2 0 0 2 2 2 1 Groucho/TLE N-terminal Q-rich domain RRF PF01765.14 EPY50866.1 - 0.0073 15.7 4.4 0.042 13.2 0.1 2.9 2 1 0 2 2 2 1 Ribosome recycling factor PLU-1 PF08429.6 EPY50866.1 - 0.015 14.1 0.4 0.015 14.1 0.2 2.3 2 0 0 2 2 2 0 PLU-1-like protein SEO_N PF14576.1 EPY50866.1 - 0.023 14.0 5.5 0.036 13.3 0.2 2.6 2 1 0 2 2 2 0 Sieve element occlusion N-terminus V_ATPase_I PF01496.14 EPY50866.1 - 0.23 9.2 5.6 0.28 8.9 1.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Bacillus_HBL PF05791.6 EPY50866.1 - 2 7.7 11.1 4.6 6.5 1.3 3.8 3 2 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ICMT PF04140.9 EPY50867.1 - 3.6e-28 97.6 1.2 7e-28 96.6 0.8 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EPY50867.1 - 2.3e-14 53.3 0.9 2.3e-14 53.3 0.6 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 EPY50867.1 - 1.7e-05 24.2 2.2 2.7e-05 23.6 1.5 1.4 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 EPY50867.1 - 0.0026 17.1 0.5 0.0041 16.4 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Sterol-sensing PF12349.3 EPY50867.1 - 0.0045 16.4 0.4 0.0045 16.4 0.3 1.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SSF PF00474.12 EPY50867.1 - 0.028 13.0 0.1 0.028 13.0 0.1 1.6 2 0 0 2 2 2 0 Sodium:solute symporter family Steroid_dh PF02544.11 EPY50867.1 - 0.16 11.7 5.7 0.11 12.2 2.6 1.7 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Aminotran_1_2 PF00155.16 EPY50868.1 - 1.7e-73 247.6 0.0 1.9e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ABC1 PF03109.11 EPY50869.1 - 1.1e-29 102.8 0.3 2.2e-29 101.8 0.2 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EPY50869.1 - 0.01 15.5 0.0 0.57 9.8 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.6 EPY50869.1 - 0.025 13.8 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) UPF0300 PF08594.5 EPY50870.1 - 1e-68 230.4 0.9 1.4e-68 230.0 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Endosulfine PF04667.12 EPY50871.1 - 7.5e-21 73.9 0.0 9.9e-21 73.5 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region PP2C PF00481.16 EPY50872.1 - 2.4e-42 145.0 0.0 3.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPY50872.1 - 2.4e-05 23.8 0.0 6.3e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_tran_28_C PF04101.11 EPY50873.1 - 6.6e-32 110.4 0.0 8.4e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EPY50873.1 - 0.00074 18.8 0.0 0.0009 18.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Recep_L_domain PF01030.19 EPY50874.1 - 0.00037 20.4 0.1 0.00037 20.4 0.1 1.1 1 0 0 1 1 1 1 Receptor L domain Aminotran_1_2 PF00155.16 EPY50875.1 - 1.1e-20 73.8 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPY50875.1 - 8.9e-07 27.8 0.0 1.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EPY50875.1 - 0.00068 18.7 0.0 0.0019 17.3 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family ACC_central PF08326.7 EPY50876.1 - 3e-257 855.3 0.0 3.8e-257 855.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EPY50876.1 - 1.6e-176 587.4 0.0 2.1e-176 587.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EPY50876.1 - 1.1e-53 181.6 0.1 2.4e-53 180.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EPY50876.1 - 6.1e-24 84.2 0.1 1.3e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPY50876.1 - 3e-20 72.2 0.0 3.5e-19 68.7 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EPY50876.1 - 2e-16 59.3 0.3 4.9e-16 58.1 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EPY50876.1 - 4.4e-12 46.1 0.0 1.2e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPY50876.1 - 2.1e-07 30.0 0.0 0.00091 18.0 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPY50876.1 - 2.1e-05 24.0 0.0 4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EPY50876.1 - 0.0024 17.7 0.1 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EPY50876.1 - 0.012 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF788 PF05620.6 EPY50877.1 - 3e-46 157.3 1.3 3.4e-46 157.2 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) ETRAMP PF09716.5 EPY50877.1 - 0.25 11.3 1.7 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) FA_desaturase PF00487.19 EPY50877.1 - 2.6 7.4 7.4 3.5 7.0 5.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF2101 PF09874.4 EPY50877.1 - 6.4 6.2 8.4 8 5.8 5.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) G_glu_transpept PF01019.16 EPY50878.1 - 1.7e-151 505.2 0.0 2.1e-151 504.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Acetyltransf_1 PF00583.19 EPY50879.1 - 2.9e-06 27.2 0.1 6.9e-06 26.0 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY50879.1 - 2.1e-05 24.5 0.0 6.2e-05 23.0 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY50879.1 - 5.5e-05 23.0 0.0 0.0006 19.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPY50879.1 - 0.029 14.4 0.0 0.046 13.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY50879.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EPY50879.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3295 PF11702.3 EPY50880.1 - 9.1e-31 107.4 46.6 2.5e-30 105.9 32.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EPY50880.1 - 3.5e-12 45.6 4.9 7.5e-12 44.6 3.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3531 PF12049.3 EPY50880.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) Cpn60_TCP1 PF00118.19 EPY50881.1 - 1.8e-147 491.8 2.7 2.1e-147 491.6 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PCI PF01399.22 EPY50882.1 - 9.8e-20 70.8 1.4 2.1e-19 69.7 0.0 2.4 3 0 0 3 3 3 1 PCI domain Rsm22 PF09243.5 EPY50883.1 - 8.6e-39 133.2 0.0 1.2e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 CtaG_Cox11 PF04442.9 EPY50883.1 - 6.6e-22 77.9 2.2 7.1e-18 64.8 0.4 2.5 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein CtaG/Cox11 Methyltransf_18 PF12847.2 EPY50883.1 - 0.0062 17.0 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY50883.1 - 0.037 13.7 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SIP1 PF04938.7 EPY50884.1 - 0.0011 18.3 0.4 0.072 12.4 0.3 2.3 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pex2_Pex12 PF04757.9 EPY50885.1 - 6.6e-21 74.7 8.1 9.3e-21 74.2 5.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EPY50885.1 - 5.1e-06 26.4 3.3 9.1e-06 25.6 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY50885.1 - 5.8e-05 22.6 1.7 0.00011 21.7 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY50885.1 - 7.6e-05 22.4 1.8 0.00013 21.6 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EPY50885.1 - 0.00013 21.7 4.3 0.00027 20.7 3.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EPY50885.1 - 0.0013 18.3 0.7 0.0022 17.6 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPY50885.1 - 0.092 12.8 1.8 0.28 11.3 1.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-LITAF-like PF10601.4 EPY50885.1 - 2.9 7.7 6.3 26 4.7 0.0 3.0 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain PCI PF01399.22 EPY50886.1 - 3.7e-16 59.3 4.4 3.7e-16 59.3 3.0 2.9 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EPY50886.1 - 3.6e-06 26.8 3.5 6.4e-06 25.9 0.3 2.3 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 YL1 PF05764.8 EPY50886.1 - 2.8 7.5 7.9 5.7 6.4 5.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L37e PF01907.14 EPY50887.1 - 2.6e-25 87.9 14.5 2.6e-25 87.9 10.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 EPY50887.1 - 0.0011 18.7 2.7 0.0017 18.1 1.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_2 PF13923.1 EPY50887.1 - 0.14 12.2 3.9 0.22 11.5 2.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY50887.1 - 0.14 11.8 3.5 0.22 11.2 2.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 EPY50887.1 - 0.22 11.2 1.1 0.31 10.7 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EPY50887.1 - 0.52 9.5 3.7 1.9 7.8 2.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-CCHC_5 PF14787.1 EPY50887.1 - 0.85 9.1 6.2 1.7 8.2 4.3 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C3HC4 PF00097.20 EPY50887.1 - 0.9 9.2 5.4 1.4 8.6 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_RNApol_7kD PF03604.8 EPY50887.1 - 6.1 6.4 6.8 4.5 6.8 1.0 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_4 PF13894.1 EPY50887.1 - 8.5 6.9 6.8 3.9e+02 1.7 4.7 2.6 1 1 0 1 1 1 0 C2H2-type zinc finger tRNA_int_endo PF01974.12 EPY50888.1 - 5.6e-18 64.5 0.0 9.8e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EPY50888.1 - 4.3e-05 22.9 0.0 0.41 10.2 0.0 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Tropomyosin_1 PF12718.2 EPY50889.1 - 0.0031 17.3 2.1 0.0031 17.3 1.4 2.8 2 2 1 3 3 3 1 Tropomyosin like Atg14 PF10186.4 EPY50889.1 - 0.01 14.7 10.6 0.075 11.9 3.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 EPY50889.1 - 0.034 13.5 18.6 0.2 11.0 7.4 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease COG5 PF10392.4 EPY50889.1 - 0.19 11.6 7.8 0.079 12.9 1.5 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Vac_Fusion PF02346.11 EPY50889.1 - 0.3 10.5 4.5 0.26 10.7 0.3 2.6 2 1 0 2 2 2 0 Chordopoxvirus fusion protein Prefoldin_3 PF13758.1 EPY50889.1 - 0.32 10.7 5.2 1.6 8.5 1.6 2.6 2 0 0 2 2 2 0 Prefoldin subunit TMCO5 PF14992.1 EPY50889.1 - 0.33 10.0 21.8 0.052 12.6 12.5 1.5 2 0 0 2 2 2 0 TMCO5 family ATG16 PF08614.6 EPY50889.1 - 0.38 10.5 23.5 0.56 10.0 1.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 EPY50889.1 - 0.39 11.1 16.3 0.096 13.0 1.5 3.5 3 1 0 3 3 2 0 SlyX Lzipper-MIP1 PF14389.1 EPY50889.1 - 0.44 10.6 16.5 0.35 10.9 5.9 3.2 2 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 RE_Alw26IDE PF09665.5 EPY50889.1 - 1.1 7.8 7.3 0.66 8.6 4.1 1.3 1 1 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF1664 PF07889.7 EPY50889.1 - 1.2 8.9 7.3 0.71 9.6 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Uds1 PF15456.1 EPY50889.1 - 1.6 8.7 14.9 0.25 11.3 6.2 2.8 2 1 0 2 2 2 0 Up-regulated During Septation DivIVA PF05103.8 EPY50889.1 - 2.1 8.4 18.9 0.48 10.4 0.5 3.8 2 1 2 4 4 4 0 DivIVA protein COG2 PF06148.6 EPY50889.1 - 2.5 7.9 11.5 5 7.0 3.6 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.1 EPY50889.1 - 3 8.3 12.9 14 6.1 1.1 3.6 1 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EPY50889.1 - 3.5 7.1 29.4 0.2 11.2 10.1 2.6 1 1 1 2 2 2 0 IncA protein Bap31 PF05529.7 EPY50889.1 - 3.5 7.0 14.5 0.17 11.3 1.4 3.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like KLRAQ PF10205.4 EPY50889.1 - 4.4 7.4 16.0 1.4 9.0 1.3 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF1003 PF06210.6 EPY50889.1 - 5.3 7.0 6.7 5.7 6.9 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) EOS1 PF12326.3 EPY50890.1 - 4.4e-46 156.2 9.6 4.4e-46 156.2 6.7 1.6 2 0 0 2 2 2 1 N-glycosylation protein FtsJ PF01728.14 EPY50891.1 - 7e-26 91.3 0.0 1.2e-25 90.5 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EPY50891.1 - 0.0076 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RBD-FIP PF09457.5 EPY50892.1 - 0.068 12.9 0.6 0.068 12.9 0.4 2.5 3 0 0 3 3 3 0 FIP domain bZIP_1 PF00170.16 EPY50892.1 - 0.47 10.4 8.1 6.2 6.8 0.1 3.5 3 0 0 3 3 3 0 bZIP transcription factor DMPK_coil PF08826.5 EPY50892.1 - 0.57 10.1 10.3 4.6 7.2 0.1 3.0 3 1 0 3 3 3 0 DMPK coiled coil domain like bZIP_2 PF07716.10 EPY50892.1 - 1.2 9.0 11.9 1.5 8.7 0.6 2.8 2 1 0 2 2 2 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 EPY50892.1 - 5.8 6.6 10.5 6.8 6.4 2.0 3.2 3 1 0 3 3 3 0 Sperm tail C-terminal domain IncA PF04156.9 EPY50892.1 - 7.7 6.0 14.0 16 4.9 9.7 1.6 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EPY50892.1 - 8.9 5.8 9.6 1e+02 2.4 5.7 2.7 2 1 0 2 2 2 0 Septum formation initiator OST3_OST6 PF04756.8 EPY50893.1 - 1.4e-18 66.9 2.5 3e-18 65.8 1.7 1.5 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EPY50893.1 - 4.6e-07 29.4 0.0 7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Mito_carr PF00153.22 EPY50894.1 - 2.9e-67 222.4 2.1 1.2e-22 79.3 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EPY50894.1 - 0.14 12.0 0.9 16 5.3 0.1 2.4 2 0 0 2 2 2 0 UcrQ family Ribosomal_L18e PF00828.14 EPY50895.1 - 1e-27 97.0 0.3 1e-27 97.0 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Pput2613-deam PF14427.1 EPY50895.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Pput_2613-like deaminase 6PF2K PF01591.13 EPY50896.1 - 7.4e-76 254.1 0.0 1.2e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPY50896.1 - 4.4e-22 78.8 0.1 3.8e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EPY50896.1 - 4.2e-06 26.7 0.0 4.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPY50896.1 - 0.0042 17.8 0.0 0.015 16.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EPY50896.1 - 0.011 14.9 0.0 0.026 13.7 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2313 PF10076.4 EPY50896.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) DUF3014 PF11219.3 EPY50896.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) adh_short PF00106.20 EPY50897.1 - 0.0014 18.6 0.0 0.0015 18.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase HIG_1_N PF04588.8 EPY50898.1 - 2.9e-05 23.7 0.2 5.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region RhoGAP PF00620.22 EPY50899.1 - 8.5e-23 80.6 0.4 1.4e-22 79.8 0.3 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 EPY50899.1 - 2.7e-19 69.5 1.9 2.7e-19 69.5 1.3 1.9 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain Sigma54_activ_2 PF14532.1 EPY50899.1 - 0.0018 18.3 0.2 0.0049 16.9 0.1 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain CRAL_TRIO PF00650.15 EPY50899.1 - 0.0078 15.7 0.3 0.017 14.6 0.2 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain SAM_2 PF07647.12 EPY50901.1 - 8.3e-15 54.3 0.1 1.7e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPY50901.1 - 2e-14 53.5 0.1 3.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EPY50901.1 - 2.4e-11 43.9 0.0 4.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain bZIP_1 PF00170.16 EPY50901.1 - 0.0093 15.9 1.1 0.021 14.7 0.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPY50901.1 - 0.019 14.7 1.0 0.046 13.5 0.7 1.7 1 0 0 1 1 1 0 Basic region leucine zipper FliD_N PF02465.13 EPY50901.1 - 0.026 14.8 1.9 0.13 12.6 1.3 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DDHD PF02862.12 EPY50901.1 - 0.048 13.4 0.2 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 DDHD domain DivIC PF04977.10 EPY50901.1 - 2 7.9 4.8 0.67 9.4 0.5 2.0 1 1 1 2 2 2 0 Septum formation initiator Ras PF00071.17 EPY50903.1 - 1.7e-34 118.5 0.4 2e-34 118.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY50903.1 - 1.1e-22 80.7 0.2 3.9e-22 78.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EPY50903.1 - 1.6e-08 34.0 0.5 1.8e-08 33.7 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPY50903.1 - 2.5e-08 33.3 0.1 2.8e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPY50903.1 - 1.3e-05 24.7 0.4 7.6e-05 22.2 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY50903.1 - 0.00096 19.0 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.6 EPY50903.1 - 0.0025 16.5 0.9 0.4 9.3 0.0 2.0 1 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EPY50903.1 - 0.003 16.2 3.5 0.02 13.5 1.4 2.5 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 EPY50903.1 - 0.0072 15.8 0.6 0.037 13.5 0.4 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TIP120 PF08623.5 EPY50904.1 - 3.3e-40 137.4 9.8 1.4e-38 132.0 1.2 5.0 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EPY50904.1 - 2.1e-17 63.1 5.9 1e-05 25.7 0.2 7.5 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.17 EPY50904.1 - 1.4e-09 37.2 4.5 0.093 12.8 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EPY50904.1 - 0.00012 22.4 1.2 17 6.0 0.0 6.8 6 2 2 8 8 8 1 HEAT-like repeat Arm PF00514.18 EPY50904.1 - 0.00018 21.1 0.6 0.59 10.0 0.0 4.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EPY50904.1 - 0.065 13.1 11.4 1.4 8.8 0.2 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) MRP-S33 PF08293.6 EPY50904.1 - 0.21 11.5 1.1 38 4.3 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit S27 AAA PF00004.24 EPY50905.1 - 4e-99 327.9 0.0 6.6e-49 165.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPY50905.1 - 6.2e-20 70.9 1.0 1.8e-19 69.4 0.7 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EPY50905.1 - 1.5e-14 54.2 0.0 8.7e-08 32.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPY50905.1 - 1.8e-13 50.1 0.0 7.7e-06 25.1 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPY50905.1 - 1.4e-12 47.6 0.0 6.3e-06 26.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EPY50905.1 - 1.4e-11 44.2 2.5 5.2e-06 26.2 0.1 4.7 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPY50905.1 - 2.7e-11 44.3 0.0 0.00054 20.7 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EPY50905.1 - 8.8e-11 42.0 2.8 0.0023 18.0 0.1 4.8 4 2 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EPY50905.1 - 6.4e-10 39.3 0.1 0.0021 18.0 0.0 4.0 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 EPY50905.1 - 1.2e-09 37.4 0.1 0.001 17.8 0.0 2.8 2 1 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EPY50905.1 - 1.1e-08 34.7 0.0 0.0011 18.4 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein CDC48_2 PF02933.12 EPY50905.1 - 2.2e-08 33.6 0.0 6.8e-08 32.0 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EPY50905.1 - 9.5e-08 32.0 0.0 0.0035 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EPY50905.1 - 1.6e-07 30.7 0.4 0.019 14.1 0.0 2.8 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EPY50905.1 - 1.8e-07 30.4 0.0 0.0063 15.6 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EPY50905.1 - 3.4e-07 29.8 5.0 0.079 12.3 0.1 4.4 2 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 EPY50905.1 - 5e-07 29.3 2.0 0.015 15.0 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EPY50905.1 - 7.2e-07 29.3 0.0 0.036 14.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EPY50905.1 - 7.4e-07 29.5 0.0 0.017 15.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EPY50905.1 - 4.8e-06 26.5 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EPY50905.1 - 4.9e-06 25.8 1.2 0.44 9.6 0.1 3.6 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 EPY50905.1 - 7.1e-06 25.0 0.1 0.03 13.1 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EPY50905.1 - 7.7e-06 26.2 0.0 0.089 13.0 0.0 4.2 4 1 0 4 4 3 1 ABC transporter AAA_28 PF13521.1 EPY50905.1 - 8.1e-06 25.8 0.2 0.15 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EPY50905.1 - 1.1e-05 25.0 0.0 0.29 10.5 0.0 3.6 2 2 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EPY50905.1 - 2e-05 23.6 0.0 0.024 13.5 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EPY50905.1 - 3.2e-05 23.7 0.4 7.8 6.1 0.0 4.5 3 2 2 5 5 5 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EPY50905.1 - 3.6e-05 23.8 0.0 0.32 11.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EPY50905.1 - 4.9e-05 23.0 0.0 0.27 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EPY50905.1 - 5.1e-05 22.6 0.2 0.18 11.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 EPY50905.1 - 0.00017 21.2 0.0 0.24 10.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EPY50905.1 - 0.00036 20.1 0.0 0.89 9.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EPY50905.1 - 0.00044 19.3 0.0 0.65 8.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 EPY50905.1 - 0.00049 19.8 0.0 0.62 9.6 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.7 EPY50905.1 - 0.0005 19.7 0.1 1.5 8.4 0.0 3.4 3 0 0 3 3 3 1 NACHT domain NTPase_1 PF03266.10 EPY50905.1 - 0.002 17.8 0.5 1.3 8.7 0.0 4.0 4 0 0 4 4 3 1 NTPase AAA_30 PF13604.1 EPY50905.1 - 0.002 17.7 1.6 1.7 8.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 EPY50905.1 - 0.0028 16.6 0.0 0.26 10.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EPY50905.1 - 0.0037 16.8 0.0 0.45 10.0 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Molydop_binding PF01568.16 EPY50905.1 - 0.0059 16.4 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain NB-ARC PF00931.17 EPY50905.1 - 0.0068 15.3 0.1 1.8 7.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 EPY50905.1 - 0.0074 15.7 0.9 1.4 8.3 0.0 3.6 3 1 1 4 4 4 1 AAA-like domain IPT PF01745.11 EPY50905.1 - 0.012 14.8 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EPY50905.1 - 0.026 13.5 0.3 0.9 8.4 0.0 2.9 2 2 2 4 4 4 0 KAP family P-loop domain SKI PF01202.17 EPY50905.1 - 0.033 14.0 0.0 4 7.2 0.0 2.9 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EPY50905.1 - 0.039 13.5 0.1 4 7.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EPY50905.1 - 0.048 12.8 0.4 4.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 eIF-1a PF01176.14 EPY50905.1 - 0.09 12.2 0.8 2 7.8 0.1 2.9 2 1 1 3 3 3 0 Translation initiation factor 1A / IF-1 Zot PF05707.7 EPY50905.1 - 0.1 12.0 0.2 12 5.3 0.1 3.6 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) zf-C2H2 PF00096.21 EPY50906.1 - 1.4e-11 44.0 3.6 4.2e-06 26.7 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY50906.1 - 8.4e-09 35.1 4.0 0.00027 21.0 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPY50906.1 - 4.4e-07 29.8 6.6 5.9e-05 23.1 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain DUF1644 PF07800.7 EPY50906.1 - 0.34 10.7 4.8 0.61 9.9 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) SNARE PF05739.14 EPY50907.1 - 3.6e-14 52.1 4.6 3.6e-14 52.1 3.2 2.9 3 0 0 3 3 3 1 SNARE domain Tropomyosin PF00261.15 EPY50907.1 - 0.00018 20.6 8.6 0.0034 16.5 0.4 2.1 2 0 0 2 2 2 2 Tropomyosin DUF3418 PF11898.3 EPY50907.1 - 0.001 17.5 1.8 0.0017 16.8 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) Tropomyosin_1 PF12718.2 EPY50907.1 - 0.0022 17.8 6.6 0.018 14.8 0.2 2.4 2 0 0 2 2 2 1 Tropomyosin like DegS PF05384.6 EPY50907.1 - 0.0061 15.7 0.2 0.0061 15.7 0.2 2.5 2 1 0 2 2 2 1 Sensor protein DegS DivIVA PF05103.8 EPY50907.1 - 0.026 14.5 1.4 0.026 14.5 1.0 2.4 2 1 0 2 2 2 0 DivIVA protein Sec20 PF03908.8 EPY50907.1 - 0.028 14.1 4.3 0.031 13.9 0.1 2.6 2 2 0 2 2 2 0 Sec20 ORF6C PF10552.4 EPY50907.1 - 0.038 13.7 1.7 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 ORF6C domain BCIP PF13862.1 EPY50907.1 - 0.04 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Use1 PF09753.4 EPY50907.1 - 0.066 12.6 6.7 1.2 8.4 4.6 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF3585 PF12130.3 EPY50907.1 - 0.081 12.7 7.9 0.079 12.8 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3585) MerR-DNA-bind PF09278.6 EPY50907.1 - 0.4 11.1 5.8 40 4.6 0.2 3.4 3 0 0 3 3 3 0 MerR, DNA binding DUF607 PF04678.8 EPY50907.1 - 0.52 10.2 2.6 5.3 6.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF607 Laminin_II PF06009.7 EPY50907.1 - 0.55 9.9 8.6 5.6 6.7 1.9 2.7 2 1 0 2 2 2 0 Laminin Domain II DUF745 PF05335.8 EPY50907.1 - 0.92 8.9 10.7 0.25 10.8 1.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Nop16 PF09420.5 EPY50907.1 - 1.5 8.9 9.1 2.6 8.1 6.3 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 MutS_IV PF05190.13 EPY50907.1 - 1.6 8.9 5.8 2.2 8.5 0.3 2.9 2 1 1 3 3 3 0 MutS family domain IV FlaC_arch PF05377.6 EPY50907.1 - 1.7 8.6 4.3 2.2 8.2 0.3 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EPY50907.1 - 1.7 8.4 4.7 8 6.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FliJ PF02050.11 EPY50907.1 - 2.6 8.0 18.9 3.5 7.6 2.8 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein SPX PF03105.14 EPY50907.1 - 3.5 7.3 8.6 5.3 6.7 5.9 1.2 1 0 0 1 1 1 0 SPX domain COG5 PF10392.4 EPY50907.1 - 4.4 7.2 10.2 0.23 11.4 0.6 2.4 3 0 0 3 3 2 0 Golgi transport complex subunit 5 COPI_assoc PF08507.5 EPY50908.1 - 4.3e-32 110.6 2.8 4.6e-32 110.5 1.9 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2371 PF10177.4 EPY50908.1 - 0.17 11.7 3.7 0.9 9.4 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Cg6151-P PF10233.4 EPY50908.1 - 1.2 9.1 6.7 3.9 7.4 4.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P TPK_catalytic PF04263.11 EPY50909.1 - 5.7e-34 116.3 0.0 1e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EPY50909.1 - 4.1e-15 55.2 0.1 8.4e-15 54.2 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NUDIX PF00293.23 EPY50909.1 - 1.6e-09 37.5 0.0 3.2e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Rho_GDI PF02115.12 EPY50910.1 - 1.4e-59 200.8 0.2 1.5e-59 200.7 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor MAS20 PF02064.10 EPY50911.1 - 8.4e-20 70.8 2.0 4.4e-19 68.5 1.4 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor TraI PF07057.6 EPY50911.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 DNA helicase TraI Vps51 PF08700.6 EPY50912.1 - 4.6e-05 23.1 1.7 0.00012 21.8 0.3 2.4 2 0 0 2 2 2 1 Vps51/Vps67 RdRP PF05183.7 EPY50913.1 - 1.2e-160 536.0 0.1 1.6e-160 535.6 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase GATase_5 PF13507.1 EPY50914.1 - 7.9e-94 313.3 0.0 1.1e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EPY50914.1 - 1.7e-45 154.7 0.0 1.9e-25 89.6 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EPY50914.1 - 9e-23 80.3 0.2 4.4e-22 78.1 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Tau95 PF09734.4 EPY50915.1 - 4.9e-60 203.4 0.1 7.5e-60 202.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit TFIIF_beta PF02270.10 EPY50915.1 - 0.038 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit B56 PF01603.15 EPY50916.1 - 1.8e-48 165.2 10.4 2.9e-33 115.0 1.2 3.1 1 1 2 3 3 3 3 Protein phosphatase 2A regulatory B subunit (B56 family) polyprenyl_synt PF00348.12 EPY50917.1 - 5.1e-72 241.8 0.0 6e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 EPY50918.1 - 2.7e-38 130.9 6.3 3.5e-38 130.5 1.8 2.5 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EPY50918.1 - 1.7e-30 103.3 17.5 1.6e-05 24.3 0.2 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 EPY50918.1 - 3.9e-26 90.4 20.2 1e-07 31.5 0.5 7.0 4 1 4 8 8 8 7 TPR repeat TPR_2 PF07719.12 EPY50918.1 - 2.4e-24 83.2 30.1 0.00016 21.3 0.2 9.5 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 EPY50918.1 - 2.7e-21 73.6 16.6 0.00052 19.5 0.0 9.2 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPY50918.1 - 3.7e-20 72.0 13.1 0.00047 20.7 0.0 6.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPY50918.1 - 7e-19 66.6 11.1 0.085 13.5 0.0 8.6 5 2 4 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50918.1 - 9.2e-17 60.7 19.2 0.00043 20.1 0.0 7.2 5 1 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPY50918.1 - 1.1e-16 59.1 10.0 0.0058 16.3 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPY50918.1 - 6.4e-13 48.8 13.5 0.00086 19.6 0.1 6.8 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPY50918.1 - 7.1e-10 38.2 16.1 0.026 14.6 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EPY50918.1 - 1.5e-09 37.8 17.3 0.0099 15.9 0.3 6.0 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPY50918.1 - 8.7e-08 32.1 23.8 0.8 10.2 0.0 9.2 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPY50918.1 - 2.5e-06 27.2 12.0 10 6.1 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 EPY50918.1 - 1.5e-05 24.7 8.9 0.28 11.0 0.3 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 EPY50918.1 - 0.0022 16.8 0.3 2.9 6.5 0.1 3.2 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.2 EPY50918.1 - 0.0096 15.7 1.1 0.82 9.4 0.1 2.9 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) BTAD PF03704.12 EPY50918.1 - 0.17 12.1 6.7 0.33 11.2 1.1 3.5 3 1 0 3 3 3 0 Bacterial transcriptional activator domain RPN7 PF10602.4 EPY50918.1 - 0.85 8.9 7.8 7.6 5.8 0.0 4.7 5 1 1 6 6 6 0 26S proteasome subunit RPN7 TPR_11 PF13414.1 EPY50919.1 - 2.1e-31 107.3 8.0 2.8e-12 46.0 0.2 6.7 4 2 3 8 8 8 5 TPR repeat TPR_1 PF00515.23 EPY50919.1 - 2.1e-28 96.6 1.7 2.5e-06 26.8 0.1 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPY50919.1 - 4.9e-26 88.5 9.0 0.00014 21.5 0.1 9.3 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPY50919.1 - 6.2e-26 90.1 11.0 3e-09 36.6 0.0 7.7 3 2 4 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EPY50919.1 - 6.1e-23 80.7 12.5 1.5e-16 60.3 1.8 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EPY50919.1 - 6.3e-22 75.6 1.3 5.9e-05 22.5 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPY50919.1 - 7e-15 54.1 0.7 0.0042 17.5 0.2 7.9 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPY50919.1 - 8.5e-15 53.3 11.4 5.6e-05 22.6 0.0 8.1 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPY50919.1 - 5.3e-12 46.0 0.1 0.018 15.6 0.0 5.4 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPY50919.1 - 2.6e-10 40.4 6.6 0.017 15.4 0.2 6.4 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPY50919.1 - 9e-06 25.5 0.1 16 5.9 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 EPY50919.1 - 1.4e-05 24.2 3.3 0.083 11.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPY50919.1 - 1.6e-05 24.6 0.1 0.45 10.5 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.2 EPY50919.1 - 0.013 15.3 0.0 4.5 7.0 0.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 EPY50919.1 - 0.015 15.6 12.4 7.2 7.3 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat rRNA_proc-arch PF13234.1 EPY50920.1 - 2.5e-89 299.0 1.3 4.6e-89 298.1 0.6 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EPY50920.1 - 5.9e-66 221.1 1.8 7.6e-66 220.7 0.2 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EPY50920.1 - 1e-21 77.1 0.2 4.1e-21 75.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY50920.1 - 6.3e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPY50920.1 - 0.017 15.2 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EPY50920.1 - 0.018 13.9 0.0 0.041 12.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Suf PF05843.9 EPY50921.1 - 3.6e-79 266.3 2.0 3e-74 250.2 0.0 4.3 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EPY50921.1 - 0.0023 18.4 4.2 10 7.0 0.0 6.0 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPY50921.1 - 0.11 12.3 0.5 10 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Nup35_RRM PF05172.8 EPY50922.1 - 7.5e-26 89.8 0.0 1.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EPY50922.1 - 5.8e-09 35.5 0.0 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EPY50923.1 - 7.5e-26 89.8 0.0 1.5e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EPY50923.1 - 5.8e-09 35.5 0.0 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EPY50924.1 - 8.5e-54 182.4 0.0 2.2e-53 181.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50924.1 - 2.6e-35 121.7 0.2 1.9e-22 79.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPY50924.1 - 0.00017 20.6 0.0 0.00056 18.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like ZYG-11_interact PF05884.7 EPY50924.1 - 0.76 8.8 2.8 1.4 7.9 1.9 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 APH PF01636.18 EPY50924.1 - 1.5 8.4 4.3 0.6 9.8 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cyclin PF08613.6 EPY50925.1 - 2.2e-22 80.0 0.5 2.2e-22 80.0 0.4 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EPY50925.1 - 0.086 12.4 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pkinase PF00069.20 EPY50926.1 - 1.8e-62 210.8 0.0 2.5e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY50926.1 - 1.3e-34 119.4 0.0 2e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY50926.1 - 0.00075 18.5 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pro_isomerase PF00160.16 EPY50927.1 - 1.5e-49 168.1 0.0 1.9e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RhoGEF PF00621.15 EPY50928.1 - 6.4e-07 29.4 5.4 0.00014 21.7 2.1 2.7 2 1 0 2 2 2 1 RhoGEF domain Sgf11 PF08209.6 EPY50929.1 - 2e-13 49.3 1.3 2e-13 49.3 0.9 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EPY50929.1 - 0.0058 16.2 3.0 0.0087 15.6 0.1 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.3 EPY50929.1 - 0.095 12.1 3.2 0.18 11.2 2.2 1.4 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Fer4_10 PF13237.1 EPY50929.1 - 0.28 10.9 5.5 0.45 10.3 3.8 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain WD40 PF00400.27 EPY50930.1 - 9.8e-62 202.8 22.9 4.2e-11 42.2 1.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EPY50930.1 - 1.1e-15 57.0 1.4 2.6e-15 55.8 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPY50930.1 - 3.6e-11 42.4 2.1 1.6e-10 40.3 0.6 2.5 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EPY50930.1 - 4.4e-07 28.4 8.2 0.063 11.4 0.0 4.9 1 1 3 5 5 5 4 Nucleoporin Nup120/160 DnaJ PF00226.26 EPY50930.1 - 0.0013 18.4 0.1 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PRANC PF09372.5 EPY50930.1 - 0.0067 16.3 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 PRANC domain BBS2_Mid PF14783.1 EPY50930.1 - 0.022 14.5 0.0 26 4.6 0.0 3.8 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF218 PF02698.12 EPY50931.1 - 7.2e-06 25.5 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Abhydrolase_6 PF12697.2 EPY50932.1 - 9.2e-28 97.6 0.0 1.2e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY50932.1 - 1.2e-20 74.1 0.0 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPY50932.1 - 4.9e-17 62.0 0.0 1.2e-16 60.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPY50932.1 - 8.1e-05 22.9 0.0 0.00095 19.4 0.0 2.4 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_2 PF02230.11 EPY50932.1 - 0.00013 21.5 0.0 0.1 11.9 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EPY50932.1 - 0.00017 21.2 0.0 0.0025 17.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EPY50932.1 - 0.00033 20.3 0.0 0.00085 18.9 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EPY50932.1 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF3530 PF12048.3 EPY50932.1 - 0.0018 17.3 0.0 0.0063 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3530) Lipase_3 PF01764.20 EPY50932.1 - 0.0031 17.1 0.1 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.8 EPY50932.1 - 0.0034 16.9 0.0 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase UPF0227 PF05728.7 EPY50932.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.3 EPY50932.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase BAAT_C PF08840.6 EPY50932.1 - 0.02 14.5 0.0 0.095 12.3 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EPY50932.1 - 0.11 11.9 0.2 0.78 9.1 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF900 PF05990.7 EPY50932.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) La PF05383.12 EPY50933.1 - 1.6e-23 82.2 0.0 2.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EPY50933.1 - 3.1e-06 26.7 0.5 5.3e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50933.1 - 0.00087 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 EPY50934.1 - 6e-23 80.8 0.4 6e-23 80.8 0.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPY50934.1 - 3.8e-16 59.2 0.5 3.8e-16 59.2 0.4 1.6 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 EPY50934.1 - 0.15 12.3 0.8 0.2 11.8 0.1 1.5 1 1 1 2 2 2 0 YABBY protein CHCH PF06747.8 EPY50935.1 - 5.7e-06 26.1 7.7 1.2e-05 25.0 5.4 1.6 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EPY50935.1 - 0.00069 19.6 2.9 0.002 18.2 2.0 1.7 1 0 0 1 1 1 1 GCK domain UNC45-central PF11701.3 EPY50935.1 - 0.058 13.0 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DHO_dh PF01180.16 EPY50936.1 - 1.3e-113 378.8 0.0 1.5e-113 378.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EPY50936.1 - 0.0031 16.8 1.1 0.16 11.2 0.0 2.6 2 1 1 3 3 3 1 PcrB family FMN_dh PF01070.13 EPY50936.1 - 0.0058 15.5 0.0 0.04 12.7 0.0 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EPY50936.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Dus PF01207.12 EPY50936.1 - 0.066 12.0 0.0 1.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Response_reg PF00072.19 EPY50936.1 - 0.1 12.5 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Response regulator receiver domain His_biosynth PF00977.16 EPY50936.1 - 0.13 11.5 0.1 2.8 7.1 0.0 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein DNA_ligase_A_M PF01068.16 EPY50937.1 - 6.3e-66 221.5 0.2 1.2e-65 220.6 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPY50937.1 - 8e-50 169.0 0.2 1.6e-49 168.1 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPY50937.1 - 3.6e-27 94.6 0.0 1.9e-26 92.2 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EPY50937.1 - 0.00086 19.0 0.2 0.036 13.7 0.1 2.5 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 EPY50937.1 - 0.016 14.8 0.2 6.4 6.5 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain DDHD PF02862.12 EPY50938.1 - 1.1e-49 169.3 4.5 2.1e-49 168.3 1.0 2.7 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.9 EPY50938.1 - 0.065 12.5 0.1 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Sugar_tr PF00083.19 EPY50939.1 - 1.7e-109 366.3 29.0 2e-109 366.1 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY50939.1 - 1.6e-25 89.5 21.7 1.6e-25 89.5 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EPY50939.1 - 0.0035 15.5 13.2 0.088 10.9 2.6 2.5 2 1 1 3 3 3 3 Transmembrane secretion effector ETF_QO PF05187.8 EPY50940.1 - 3e-37 126.9 0.0 5e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase Thi4 PF01946.12 EPY50940.1 - 3.5e-08 32.8 0.0 9e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EPY50940.1 - 3.2e-07 29.5 0.5 0.00064 18.7 0.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPY50940.1 - 1.1e-06 27.8 0.7 0.0025 16.7 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPY50940.1 - 1.3e-05 25.0 0.1 9e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPY50940.1 - 8.8e-05 22.6 0.1 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPY50940.1 - 0.00013 21.8 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPY50940.1 - 0.00018 21.4 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPY50940.1 - 0.00041 19.5 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPY50940.1 - 0.001 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPY50940.1 - 0.0014 17.1 0.7 0.0022 16.5 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EPY50940.1 - 0.011 14.6 0.1 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.2 EPY50940.1 - 0.017 15.5 0.6 0.039 14.3 0.4 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 EPY50940.1 - 0.29 9.9 1.1 0.42 9.4 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EPY50940.1 - 0.35 9.4 0.7 0.89 8.0 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase SH3_1 PF00018.23 EPY50941.1 - 1.1e-15 56.6 0.0 2.2e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.18 EPY50941.1 - 5.4e-15 55.3 0.2 5.4e-15 55.3 0.2 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EPY50941.1 - 1.2e-14 53.5 0.0 2.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPY50941.1 - 1.2e-10 40.6 0.0 2.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Seryl_tRNA_N PF02403.17 EPY50941.1 - 0.064 13.2 2.8 0.21 11.6 1.9 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1079 PF06435.6 EPY50941.1 - 0.13 12.1 2.6 0.79 9.7 0.0 2.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) Not1 PF04054.10 EPY50942.1 - 1.9e-108 362.7 6.0 1.9e-108 362.7 4.1 2.6 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EPY50942.1 - 3.4e-36 124.1 11.2 1.4e-35 122.1 7.8 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) ERG2_Sigma1R PF04622.7 EPY50943.1 - 1.8e-88 295.4 0.0 2e-88 295.2 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein SNF2_N PF00176.18 EPY50944.1 - 7e-59 199.0 0.1 7e-59 199.0 0.0 1.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY50944.1 - 3.2e-15 55.7 0.0 3e-14 52.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY50944.1 - 6.7e-08 32.1 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF775 PF05603.7 EPY50944.1 - 0.61 9.5 4.3 31 4.0 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF775) GNAT_acetyltr_2 PF13718.1 EPY50945.1 - 5.1e-77 257.6 0.0 9.3e-77 256.7 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EPY50945.1 - 1.5e-64 216.8 0.0 3.9e-64 215.5 0.0 1.7 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EPY50945.1 - 8.8e-40 134.3 0.1 2.5e-39 132.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EPY50945.1 - 2.8e-31 107.5 0.5 9.1e-31 105.9 0.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EPY50945.1 - 0.00012 22.2 0.3 0.95 9.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain Acetyltransf_1 PF00583.19 EPY50945.1 - 0.0031 17.5 0.0 0.0093 15.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY50945.1 - 0.0092 16.1 0.0 0.036 14.2 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain APG6 PF04111.7 EPY50946.1 - 6.3e-98 327.6 5.3 6.3e-98 327.6 3.7 1.4 2 0 0 2 2 2 1 Autophagy protein Apg6 CCDC155 PF14662.1 EPY50946.1 - 0.039 13.5 11.7 0.064 12.8 8.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF869 PF05911.6 EPY50946.1 - 0.37 8.9 16.6 0.54 8.4 11.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) zf-AD PF07776.10 EPY50946.1 - 0.41 10.6 3.0 7.2 6.6 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Transposase_22 PF02994.9 EPY50946.1 - 0.54 8.7 9.1 1.3 7.4 5.1 2.2 2 1 1 3 3 3 0 L1 transposable element IncA PF04156.9 EPY50946.1 - 0.62 9.6 17.5 1.7 8.1 12.2 1.7 1 1 0 1 1 1 0 IncA protein Spc24 PF08286.6 EPY50946.1 - 0.91 9.2 12.0 9 6.0 0.1 3.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.17 EPY50946.1 - 2.3 8.2 10.9 0.15 12.0 2.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pyrophosphatase PF00719.14 EPY50947.1 - 5.3e-46 155.8 0.0 7.9e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Integrase_Zn PF02022.14 EPY50947.1 - 0.0048 16.3 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain zf-RING_2 PF13639.1 EPY50948.1 - 6e-14 51.5 4.8 6e-14 51.5 3.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPY50948.1 - 8.3e-09 35.3 4.6 8.3e-09 35.3 3.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPY50948.1 - 2.8e-08 33.7 5.5 9.5e-08 32.0 3.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPY50948.1 - 5.6e-08 32.3 3.3 5.6e-08 32.3 2.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPY50948.1 - 6.3e-08 32.1 4.1 6.3e-08 32.1 2.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY50948.1 - 9.8e-08 31.5 1.1 9.8e-08 31.5 0.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPY50948.1 - 2.1e-05 24.2 5.1 0.00047 19.9 3.6 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EPY50948.1 - 0.00094 18.8 0.1 0.00094 18.8 0.1 2.1 2 1 0 2 2 1 1 RING-type zinc-finger RINGv PF12906.2 EPY50948.1 - 0.0011 18.9 1.9 0.0036 17.3 1.3 1.9 1 1 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 EPY50948.1 - 0.0088 15.6 5.7 0.0088 15.6 4.0 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPY50948.1 - 0.0091 15.8 4.2 0.0091 15.8 2.9 2.6 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 EPY50948.1 - 0.046 12.9 1.1 0.079 12.1 0.5 1.6 1 1 0 1 1 1 0 Rtf2 RING-finger FANCL_C PF11793.3 EPY50948.1 - 0.087 12.8 5.6 0.73 9.8 3.9 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EPY50948.1 - 0.15 11.6 4.7 0.58 9.7 3.3 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 EPY50948.1 - 0.18 11.8 3.5 0.4 10.7 2.4 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EPY50948.1 - 2.9 7.6 9.2 0.56 9.9 2.1 2.4 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_2 PF12674.2 EPY50948.1 - 3.3 8.1 8.7 0.82 10.0 1.8 2.7 2 1 0 3 3 3 0 Putative zinc ribbon domain RNase_P_p30 PF01876.11 EPY50949.1 - 4.1e-44 149.4 0.0 5.5e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Peptidase_M1 PF01433.15 EPY50950.1 - 1.6e-11 43.9 0.2 7.3e-05 22.0 0.0 3.3 2 1 0 2 2 2 2 Peptidase family M1 HEAT_2 PF13646.1 EPY50950.1 - 0.015 15.5 0.0 0.47 10.7 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats Na_Ca_ex PF01699.19 EPY50951.1 - 9.9e-50 167.7 29.6 1.9e-26 92.3 8.8 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MRP-L27 PF09809.4 EPY50952.1 - 7.3e-14 51.3 0.1 8.6e-14 51.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RNA_pol_L_2 PF13656.1 EPY50953.1 - 3.9e-25 87.0 0.4 5.3e-25 86.6 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPY50953.1 - 2.2e-12 45.8 0.1 2.9e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain 4HBT_3 PF13622.1 EPY50954.1 - 0.031 14.0 0.2 0.12 12.1 0.0 1.9 2 1 0 2 2 2 0 Thioesterase-like superfamily UreD PF01774.12 EPY50955.1 - 3.3e-48 163.9 0.0 3.8e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein DUF999 PF06198.6 EPY50956.1 - 1.8e-06 27.7 2.5 4.9e-06 26.3 1.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF999) HemY_N PF07219.8 EPY50956.1 - 0.38 10.3 1.4 1.9 8.0 0.4 2.1 2 0 0 2 2 2 0 HemY protein N-terminus RRM_1 PF00076.17 EPY50957.1 - 4.3e-10 39.0 0.1 1.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50957.1 - 6.6e-08 32.2 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50957.1 - 4.7e-07 29.6 0.1 1.4e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY50957.1 - 0.0021 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 EPY50957.1 - 0.032 13.7 1.1 0.21 11.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) zf-CCCH PF00642.19 EPY50957.1 - 0.045 13.4 1.1 0.077 12.7 0.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pox_H7 PF04787.7 EPY50957.1 - 0.13 12.1 0.9 0.31 10.8 0.6 1.6 1 0 0 1 1 1 0 Late protein H7 Ribosomal_L18ae PF01775.12 EPY50958.1 - 5.3e-55 184.6 0.4 6.5e-55 184.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain ATP11 PF06644.6 EPY50959.1 - 1.1e-67 228.4 4.0 2.6e-67 227.1 2.8 1.5 1 1 0 1 1 1 1 ATP11 protein DUF3306 PF11748.3 EPY50959.1 - 0.069 13.8 1.0 0.11 13.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF2852 PF11014.3 EPY50959.1 - 0.11 12.4 1.2 0.17 11.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) eIF3_subunit PF08597.5 EPY50960.1 - 1.2e-43 149.5 24.4 1.3e-43 149.3 16.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3235 PF11574.3 EPY50960.1 - 0.21 11.8 7.5 1.1 9.4 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Herpes_env PF01673.13 EPY50960.1 - 7.6 4.9 10.9 2.6 6.5 5.7 1.4 1 1 1 2 2 2 0 Herpesvirus putative major envelope glycoprotein EF-hand_1 PF00036.27 EPY50961.1 - 1.3e-39 130.4 8.2 5.5e-10 37.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPY50961.1 - 2.9e-35 120.2 2.5 4.1e-19 68.4 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EPY50961.1 - 2e-33 113.7 9.6 2e-14 52.8 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EPY50961.1 - 4.3e-30 100.8 6.2 1.9e-09 36.5 0.0 4.7 4 2 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EPY50961.1 - 7.2e-26 88.3 5.8 1e-05 24.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EPY50961.1 - 1.3e-14 53.8 0.1 5.4e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EPY50961.1 - 7.1e-09 35.3 2.1 0.0017 18.0 0.0 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EPY50961.1 - 2.3e-06 27.5 0.0 0.0085 16.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 EPY50961.1 - 6e-06 26.1 0.3 6e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 EPY50961.1 - 0.00043 19.8 0.0 1.6 8.4 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 EPY50961.1 - 0.00077 19.2 0.2 0.26 10.9 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF2267 PF10025.4 EPY50961.1 - 0.0042 17.1 0.0 2.9 7.9 0.0 2.3 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2267) Caleosin PF05042.8 EPY50961.1 - 0.005 16.4 0.1 0.33 10.4 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein DUF3349 PF11829.3 EPY50961.1 - 0.0061 16.9 0.3 5.1 7.5 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) LNS2 PF08235.8 EPY50961.1 - 0.017 14.6 0.1 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF3807 PF12720.2 EPY50961.1 - 0.096 12.8 1.2 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Vps53_N PF04100.7 EPY50962.1 - 2.4e-93 312.9 15.3 2.4e-93 312.9 10.6 1.5 2 0 0 2 2 2 1 Vps53-like, N-terminal Tim17 PF02466.14 EPY50963.1 - 5.2e-33 113.8 4.8 6.5e-33 113.5 3.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PALP PF00291.20 EPY50964.1 - 1.9e-58 198.1 0.0 2.2e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme G6PD_C PF02781.11 EPY50965.1 - 2.7e-114 380.9 0.0 4.2e-114 380.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EPY50965.1 - 9.6e-65 218.2 0.0 1.4e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.19 EPY50966.1 - 3.5e-11 42.9 0.0 5.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY50966.1 - 5e-08 32.9 0.0 7.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY50966.1 - 1.7e-06 27.7 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EPY50966.1 - 4.3e-06 26.5 0.0 4.9e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPY50966.1 - 0.0012 18.6 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPY50966.1 - 0.0029 17.4 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EPY50966.1 - 0.0046 17.0 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPY50966.1 - 0.0076 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sec63 PF02889.11 EPY50967.1 - 2.1e-184 611.9 0.3 8.2e-104 347.1 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPY50967.1 - 4.2e-49 166.2 1.6 5.2e-32 110.6 0.1 4.0 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 EPY50967.1 - 2.9e-17 63.1 0.0 2.9e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPY50967.1 - 8.3e-11 41.6 0.0 1.7e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPY50967.1 - 0.00069 19.7 0.1 0.071 13.2 0.0 3.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EPY50967.1 - 0.0011 18.2 0.0 0.68 9.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein DEAD PF00270.24 EPY50968.1 - 3.2e-20 72.2 0.0 1.1e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EPY50968.1 - 5.8e-20 71.8 0.0 5.8e-20 71.8 0.0 2.7 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPY50968.1 - 1.1e-19 70.0 0.2 2.9e-19 68.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPY50968.1 - 0.0079 16.3 0.0 0.042 13.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain Aldolase_II PF00596.16 EPY50969.1 - 8.7e-13 48.2 0.0 1.1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TGS PF02824.16 EPY50970.1 - 2.2e-21 75.4 0.0 4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EPY50970.1 - 1.5e-18 66.8 0.0 3.4e-18 65.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY50970.1 - 9.5e-11 41.2 0.2 3.1e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPY50970.1 - 0.00032 20.5 0.1 0.26 11.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EPY50970.1 - 0.0078 16.6 0.0 0.021 15.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EPY50970.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 EPY50970.1 - 0.082 11.6 0.2 0.17 10.6 0.1 1.5 1 0 0 1 1 1 0 ArgK protein CCD PF07860.6 EPY50970.1 - 0.09 12.2 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 WisP family C-Terminal Region Steroid_dh PF02544.11 EPY50972.1 - 8.9e-28 96.9 6.5 3e-21 75.7 2.4 2.4 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EPY50972.1 - 5.6e-07 29.0 7.2 1.5e-06 27.7 5.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Meth_synt_2 PF01717.13 EPY50973.1 - 4.9e-143 475.9 0.0 1.5e-137 457.9 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EPY50973.1 - 9.3e-125 415.9 0.0 1.4e-114 382.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EPY50973.1 - 5.5e-05 22.2 0.0 0.26 10.1 0.0 2.8 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) AA_permease_2 PF13520.1 EPY50974.1 - 1.4e-46 158.9 42.3 1.7e-46 158.6 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPY50974.1 - 3.8e-26 91.4 35.9 5.9e-26 90.8 24.9 1.2 1 0 0 1 1 1 1 Amino acid permease ATP12 PF07542.6 EPY50976.1 - 3.4e-31 107.7 0.0 5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein Nol1_Nop2_Fmu PF01189.12 EPY50976.1 - 0.0049 16.3 0.0 0.0072 15.7 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family DUF572 PF04502.8 EPY50977.1 - 4.5e-67 226.5 10.8 5.2e-67 226.3 7.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Lar_restr_allev PF14354.1 EPY50977.1 - 0.012 15.8 0.8 1.3 9.3 0.1 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-FCS PF06467.9 EPY50977.1 - 0.074 12.7 1.0 0.074 12.7 0.7 1.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RNA_pol_N PF01194.12 EPY50977.1 - 2.7 8.0 4.8 5.2 7.1 1.4 2.5 2 1 1 3 3 3 0 RNA polymerases N / 8 kDa subunit GPP34 PF05719.6 EPY50978.1 - 1.2e-63 214.9 0.2 1.5e-63 214.5 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Grp1_Fun34_YaaH PF01184.14 EPY50980.1 - 5.6e-60 202.2 14.9 6.7e-41 139.9 4.0 2.2 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family PXA PF02194.10 EPY50982.1 - 3.6e-28 98.3 1.7 3.6e-28 98.3 1.2 2.4 3 0 0 3 3 3 1 PXA domain Alg14 PF08660.6 EPY50983.1 - 8.4e-59 198.3 0.0 1e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Med18 PF09637.5 EPY50984.1 - 5.7e-30 104.6 0.0 7.1e-29 101.0 0.0 1.9 1 1 0 1 1 1 1 Med18 protein Mem_trans PF03547.13 EPY50985.1 - 7.8e-73 244.9 2.3 9.1e-73 244.7 1.6 1.0 1 0 0 1 1 1 1 Membrane transport protein SBP_bac_3 PF00497.15 EPY50986.1 - 0.041 13.1 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Ribosomal_S8 PF00410.14 EPY50987.1 - 5e-27 94.2 0.2 6.7e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 RRM_6 PF14259.1 EPY50988.1 - 3.2e-13 49.4 0.0 9.2e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY50988.1 - 8e-08 31.8 0.0 7.7e-06 25.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50988.1 - 0.00085 19.1 0.1 0.8 9.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-met PF12874.2 EPY50988.1 - 0.0061 16.7 0.2 0.018 15.2 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-RanBP PF00641.13 EPY50988.1 - 0.11 11.6 2.7 0.27 10.3 1.9 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF3354 PF11834.3 EPY50988.1 - 0.11 12.0 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) zf-C2H2_2 PF12756.2 EPY50988.1 - 0.21 11.7 0.1 0.21 11.7 0.0 2.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) HSP70 PF00012.15 EPY50989.1 - 2.9e-79 266.6 1.5 3.8e-79 266.1 1.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPY50989.1 - 9.8e-08 30.9 0.1 1.5e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Sigma70_ner PF04546.8 EPY50989.1 - 1.5 8.3 6.1 2.1 7.9 0.1 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region Raptor_N PF14538.1 EPY50990.1 - 1.2e-67 226.5 0.2 4.4e-67 224.7 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EPY50990.1 - 1e-10 41.0 9.8 0.00051 19.8 0.3 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 EPY50990.1 - 6.4e-06 25.8 7.0 0.18 11.9 0.1 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EPY50990.1 - 0.0056 16.9 0.5 0.059 13.6 0.1 2.8 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.2 EPY50990.1 - 0.0064 16.3 0.5 0.54 10.0 0.0 2.9 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3535 PF12054.3 EPY50990.1 - 0.086 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Adaptin_N PF01602.15 EPY50991.1 - 7.1e-115 384.2 2.2 1.3e-114 383.4 1.5 1.4 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EPY50991.1 - 1.6e-47 161.1 2.3 2.9e-47 160.2 1.6 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EPY50991.1 - 5e-14 52.3 0.9 0.0017 18.6 0.0 6.2 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EPY50991.1 - 0.00038 20.2 3.1 4.3 7.6 0.2 5.4 5 0 0 5 5 5 1 HEAT repeat RICTOR_N PF14664.1 EPY50991.1 - 0.0029 16.2 0.5 0.0078 14.8 0.4 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term DNase_II PF03265.10 EPY50991.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Deoxyribonuclease II HEAT_EZ PF13513.1 EPY50991.1 - 0.69 10.4 2.3 8.9 6.9 0.3 3.6 3 1 0 3 3 3 0 HEAT-like repeat zf-RING_2 PF13639.1 EPY50992.1 - 2.7e-14 52.7 6.0 4.5e-14 52.0 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EPY50992.1 - 5.1e-10 38.9 0.0 8.8e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EPY50992.1 - 3e-09 36.7 6.9 5.5e-09 35.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPY50992.1 - 6.8e-09 35.7 2.0 1.9e-08 34.3 1.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPY50992.1 - 6.6e-08 32.0 5.7 1.2e-07 31.2 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY50992.1 - 1.2e-06 28.0 4.1 2.4e-06 27.1 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY50992.1 - 8.6e-06 25.3 5.4 1.6e-05 24.5 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPY50992.1 - 0.00031 20.5 1.0 0.00072 19.3 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EPY50992.1 - 0.0091 15.7 5.4 0.077 12.7 3.9 2.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EPY50992.1 - 0.016 14.9 2.1 0.039 13.6 1.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.6 EPY50992.1 - 0.017 14.9 0.6 0.038 13.8 0.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EPY50992.1 - 0.06 13.2 4.3 0.12 12.2 3.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPY50992.1 - 0.15 11.6 4.6 0.31 10.6 3.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EPY50992.1 - 0.17 11.9 5.7 0.38 10.8 3.9 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EPY50992.1 - 1.2 8.8 5.2 2.8 7.7 3.6 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EPY50992.1 - 1.6 8.7 7.6 2.2 8.3 4.0 2.3 2 1 0 2 2 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EPY50992.1 - 8.7 6.4 7.5 4.6 7.3 3.7 1.7 2 0 0 2 2 1 0 RING-like domain Metallophos PF00149.23 EPY50993.1 - 1.2e-39 135.7 0.2 1.8e-39 135.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase S-methyl_trans PF02574.11 EPY50994.1 - 2.8e-24 85.9 0.0 4.5e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Utp14 PF04615.8 EPY50995.1 - 1.4e-182 608.7 84.9 1.4e-182 608.7 58.8 2.0 1 1 1 2 2 2 1 Utp14 protein DUF2422 PF10337.4 EPY50996.1 - 1.2e-68 232.0 6.8 5.7e-62 209.9 2.4 4.2 5 0 0 5 5 5 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EPY50996.1 - 1.9e-64 217.4 0.1 4.6e-64 216.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EPY50996.1 - 1.6e-08 34.5 18.0 1.6e-08 34.5 12.5 2.8 3 1 0 3 3 3 1 Fusaric acid resistance protein-like WhiA_N PF10298.4 EPY50997.1 - 0.099 12.5 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain RRM_1 PF00076.17 EPY50998.1 - 3.7e-88 289.1 4.7 1.8e-23 81.9 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY50998.1 - 3.1e-57 190.4 0.7 5.7e-16 58.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY50998.1 - 3.4e-44 148.4 0.1 7.7e-11 41.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EPY50998.1 - 4.7e-26 90.2 1.0 4.7e-26 90.2 0.7 2.8 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EPY50998.1 - 3.1e-06 26.9 5.2 0.99 9.2 0.6 4.2 4 0 0 4 4 4 3 RNA binding motif CbiG_mid PF11761.3 EPY50998.1 - 5.7e-05 23.2 0.2 1.2 9.3 0.0 3.9 4 0 0 4 4 4 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 EPY50998.1 - 0.00062 19.4 0.0 1.2 8.9 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EPY50998.1 - 0.0037 16.9 4.1 0.075 12.7 0.3 3.5 4 0 0 4 4 4 1 Limkain b1 DnaI_N PF07319.6 EPY50998.1 - 0.0054 16.9 1.8 0.61 10.3 0.5 3.3 3 0 0 3 3 3 1 Primosomal protein DnaI N-terminus OB_RNB PF08206.6 EPY50998.1 - 0.022 14.2 0.5 8.4 5.9 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.3 EPY50998.1 - 0.68 10.1 6.4 0.92 9.6 0.9 3.0 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF4407 PF14362.1 EPY50998.1 - 0.85 8.5 5.9 1.8 7.4 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HECT PF00632.20 EPY50999.1 - 4e-92 308.7 0.0 1.1e-91 307.2 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ftsk_gamma PF09397.5 EPY50999.1 - 0.091 12.4 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain Usp PF00582.21 EPY51001.1 - 3.6e-21 75.8 1.0 9.5e-21 74.4 0.1 2.1 2 0 0 2 2 2 1 Universal stress protein family Pam17 PF08566.5 EPY51002.1 - 6.7e-63 211.4 0.1 8.5e-63 211.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF3613 PF12266.3 EPY51002.1 - 2.1 7.9 4.5 0.38 10.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) SART-1 PF03343.8 EPY51003.1 - 1.7e-111 373.5 71.5 2e-111 373.3 49.5 1.0 1 0 0 1 1 1 1 SART-1 family Prenyltrans PF00432.16 EPY51004.1 - 1.1e-58 194.3 2.6 4.4e-13 48.5 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPY51004.1 - 1.1e-44 151.4 0.0 6.2e-14 52.3 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPY51004.1 - 1.4e-10 41.1 0.0 1.9e-06 27.8 0.0 4.0 3 1 1 4 4 4 1 Prenyltransferase-like Peptidase_M20 PF01546.23 EPY51004.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 A2M_comp PF07678.9 EPY51004.1 - 0.019 14.2 1.0 9.9 5.3 0.0 4.1 3 2 2 5 5 5 0 A-macroglobulin complement component Propep_M14 PF02244.11 EPY51004.1 - 0.23 11.1 0.1 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Pga1 PF10333.4 EPY51005.1 - 0.00033 20.3 0.3 0.021 14.4 0.2 2.4 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Ribonuc_2-5A PF06479.7 EPY51006.1 - 1.3e-46 157.6 0.0 2.4e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EPY51006.1 - 7.4e-41 140.0 0.0 1.1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51006.1 - 1.1e-21 77.1 0.0 1.7e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 EPY51006.1 - 8.4e-08 31.9 0.1 0.00037 20.0 0.0 3.2 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 EPY51006.1 - 4.2e-07 29.1 0.0 0.069 12.7 0.0 3.6 3 0 0 3 3 3 3 PQQ enzyme repeat Recep_L_domain PF01030.19 EPY51007.1 - 1.6e-13 50.6 4.8 4.1e-05 23.5 0.1 4.5 1 1 3 5 5 5 3 Receptor L domain Ecm33 PF12454.3 EPY51007.1 - 0.066 13.0 1.8 0.086 12.7 0.1 2.1 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein LRR_5 PF13306.1 EPY51007.1 - 0.3 10.8 5.5 1.8 8.3 0.1 3.0 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) 4F5 PF04419.9 EPY51008.1 - 2.5e-08 34.4 8.5 2.5e-08 34.4 5.9 2.1 2 0 0 2 2 2 1 4F5 protein family LTXXQ PF07813.7 EPY51008.1 - 0.52 10.8 8.4 0.57 10.6 5.8 1.1 1 0 0 1 1 1 0 LTXXQ motif family protein Bravo_FIGEY PF13882.1 EPY51008.1 - 3.7 8.5 6.2 3.9 8.4 4.3 1.0 1 0 0 1 1 1 0 Bravo-like intracellular region zf-rbx1 PF12678.2 EPY51009.1 - 1.1e-35 121.5 13.1 1.4e-35 121.2 9.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPY51009.1 - 3.6e-18 65.1 9.7 4.9e-18 64.7 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EPY51009.1 - 4.3e-08 32.8 11.7 4.9e-07 29.4 8.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPY51009.1 - 0.00016 21.2 11.4 0.0014 18.2 7.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY51009.1 - 0.00034 20.2 9.5 0.0014 18.2 2.7 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY51009.1 - 0.014 15.3 11.9 0.21 11.6 8.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4001 PF13165.1 EPY51009.1 - 0.13 11.9 3.6 0.19 11.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) zf-RING_5 PF14634.1 EPY51009.1 - 0.19 11.4 11.4 1.6 8.5 7.9 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EPY51009.1 - 0.32 11.1 10.3 16 5.7 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 EPY51009.1 - 0.4 10.6 9.1 1.4 8.9 6.3 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EPY51009.1 - 0.45 10.2 6.8 11 5.7 4.7 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EPY51009.1 - 0.62 10.0 10.2 1.8 8.6 7.0 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain Pkinase PF00069.20 EPY51010.1 - 4.8e-62 209.4 0.0 6.3e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51010.1 - 1e-29 103.4 0.0 1.7e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51010.1 - 0.00025 20.1 0.0 0.00053 19.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPY51010.1 - 0.068 12.9 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family FAM104 PF15434.1 EPY51010.1 - 0.085 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Family 104 GSCFA PF08885.6 EPY51011.1 - 0.036 13.6 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 GSCFA family DUF663 PF04950.7 EPY51012.1 - 1.5e-103 345.8 0.0 4.3e-103 344.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPY51012.1 - 1.3e-18 66.2 0.0 3e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Vps39_1 PF10366.4 EPY51013.1 - 8.7e-32 109.3 0.6 4.8e-28 97.3 0.1 3.1 2 0 0 2 2 2 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EPY51013.1 - 3.4e-27 94.7 0.3 7.7e-27 93.6 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EPY51013.1 - 7.5e-19 68.2 0.2 1.3e-18 67.4 0.1 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 EPY51013.1 - 7.9e-06 25.5 3.1 7.9e-06 25.5 2.2 4.2 2 1 2 5 5 5 1 Region in Clathrin and VPS TPR_19 PF14559.1 EPY51013.1 - 2.4e-05 24.6 0.0 0.97 9.8 0.0 5.6 6 1 0 7 7 7 1 Tetratricopeptide repeat PPR PF01535.15 EPY51013.1 - 0.0014 18.4 0.0 5.1 7.3 0.0 3.9 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.1 EPY51013.1 - 0.0068 16.3 0.0 1.3 9.0 0.0 3.5 3 0 0 3 3 3 1 PPR repeat family DUF4050 PF13259.1 EPY51014.1 - 6.6e-16 58.3 2.6 7.4e-16 58.1 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) SNF2_N PF00176.18 EPY51014.1 - 0.1 11.3 0.9 0.12 11.1 0.7 1.0 1 0 0 1 1 1 0 SNF2 family N-terminal domain Tropomyosin_1 PF12718.2 EPY51015.1 - 0.049 13.4 1.5 0.051 13.4 0.6 1.4 1 1 0 1 1 1 0 Tropomyosin like Iso_dh PF00180.15 EPY51015.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase MRG PF05712.8 EPY51016.1 - 4.4e-49 166.0 0.2 8.3e-49 165.1 0.1 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EPY51016.1 - 1.2e-10 40.9 0.5 2.6e-10 39.8 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF4544 PF15077.1 EPY51016.1 - 6.2 6.2 6.3 9.3 5.6 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Cnl2_NKP2 PF09447.5 EPY51017.1 - 8.6e-20 70.1 1.7 8.6e-20 70.1 1.2 2.4 3 0 0 3 3 3 1 Cnl2/NKP2 family protein DUF2115 PF09888.4 EPY51017.1 - 0.069 13.2 1.0 2 8.5 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) AAA_23 PF13476.1 EPY51017.1 - 0.085 13.1 5.5 0.11 12.8 3.8 1.2 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EPY51017.1 - 0.087 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IZUMO PF15005.1 EPY51017.1 - 0.11 12.4 0.8 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion NPV_P10 PF05531.7 EPY51017.1 - 1.6 9.0 4.9 1.2 9.4 1.2 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GAT PF03127.9 EPY51017.1 - 4.6 7.2 7.4 13 5.8 0.1 3.4 2 2 1 3 3 3 0 GAT domain HK PF02110.10 EPY51018.1 - 8.9e-91 303.4 1.3 1.3e-90 302.9 0.9 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EPY51018.1 - 1.4e-58 197.0 1.1 3.5e-58 195.6 0.6 1.8 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Peptidase_M24 PF00557.19 EPY51019.1 - 1.5e-26 93.3 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1762 PF08574.5 EPY51020.1 - 3.8e-08 33.6 12.7 1.6e-07 31.6 8.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1762) SPR1 PF15356.1 EPY51020.1 - 3.2 8.1 7.5 0.21 11.9 1.0 2.0 2 1 0 2 2 2 0 Psoriasis susceptibility locus 2 SRPRB PF09439.5 EPY51021.1 - 2.7e-31 108.1 0.1 3.4e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EPY51021.1 - 2e-11 43.4 0.1 1e-10 41.1 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPY51021.1 - 4.3e-09 36.0 0.0 1.4e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY51021.1 - 3.4e-06 26.9 0.0 6.3e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EPY51021.1 - 0.0012 18.4 1.6 0.067 12.7 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 EPY51021.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EPY51021.1 - 0.0015 17.8 0.0 0.0034 16.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPY51021.1 - 0.0016 18.2 0.2 0.11 12.3 0.0 2.6 2 1 1 3 3 3 1 Dynamin family NACHT PF05729.7 EPY51021.1 - 0.0047 16.5 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 EPY51021.1 - 0.0048 17.2 1.3 0.023 14.9 0.9 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EPY51021.1 - 0.0053 16.4 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EPY51021.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EPY51021.1 - 0.0094 15.4 0.6 1.6 8.1 0.0 2.7 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 EPY51021.1 - 0.013 14.2 1.5 0.09 11.4 0.0 2.1 1 1 0 2 2 2 0 G-protein alpha subunit Miro PF08477.8 EPY51021.1 - 0.019 15.4 0.0 0.034 14.6 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EPY51021.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EPY51021.1 - 0.023 14.8 0.0 0.037 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY51021.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPY51021.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPY51021.1 - 0.087 12.2 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 EPY51021.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Archaeal ATPase DUF2391 PF09622.5 EPY51021.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) SRP54 PF00448.17 EPY51021.1 - 0.19 11.1 0.8 16 4.8 0.0 2.8 1 1 2 3 3 3 0 SRP54-type protein, GTPase domain Gln-synt_C PF00120.19 EPY51022.1 - 2.1e-58 197.5 0.0 2.6e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EPY51022.1 - 6.5e-19 67.3 0.0 1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain tRNA_Me_trans PF03054.11 EPY51023.1 - 3.1e-118 394.3 0.0 3.6e-118 394.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EPY51023.1 - 8.1e-05 22.1 0.0 0.00038 19.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 EPY51023.1 - 0.00074 18.4 0.0 0.009 14.9 0.0 2.1 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 EPY51023.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Herpes_heli_pri PF05774.6 EPY51023.1 - 0.024 14.6 1.3 0.028 14.3 0.1 1.6 2 0 0 2 2 2 0 Herpesvirus helicase-primase complex component ATP_bind_3 PF01171.15 EPY51023.1 - 0.073 12.5 0.0 0.25 10.8 0.0 1.9 2 1 0 2 2 2 0 PP-loop family EMP24_GP25L PF01105.19 EPY51024.1 - 9e-36 123.2 0.3 1.1e-35 123.0 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 EPY51025.1 - 7.2e-66 221.9 0.0 1e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51025.1 - 1.4e-34 119.3 0.0 2.2e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPY51025.1 - 1.7e-05 24.0 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY51025.1 - 0.0043 16.0 0.0 0.0063 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Oxysterol_BP PF01237.13 EPY51026.1 - 2.5e-101 338.7 0.0 7.9e-101 337.0 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EPY51026.1 - 8e-36 121.9 0.0 1.9e-35 120.7 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EPY51026.1 - 0.00027 21.1 0.1 0.0029 17.8 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_11 PF13414.1 EPY51027.1 - 9.9e-10 37.9 3.3 6.3e-05 22.5 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EPY51027.1 - 1.1e-07 31.1 0.7 0.031 13.8 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY51027.1 - 5.5e-07 29.0 3.7 0.028 14.3 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY51027.1 - 6.8e-06 25.9 13.1 0.0034 17.2 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.1 EPY51027.1 - 6.9e-05 22.1 3.5 0.0055 15.8 0.2 3.0 1 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.1 EPY51027.1 - 0.00014 22.2 1.0 2.6 8.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPY51027.1 - 0.0013 18.3 6.3 1.1 9.1 0.0 4.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY51027.1 - 0.0013 19.3 0.1 1.5 9.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 EPY51027.1 - 0.008 15.6 1.4 2.4 7.5 0.1 2.7 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.1 EPY51027.1 - 0.026 14.2 0.1 2.6 8.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EPY51027.1 - 0.04 13.7 2.4 4.1 7.3 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_5 PF12688.2 EPY51027.1 - 0.053 13.5 0.0 3.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat D123 PF07065.9 EPY51028.1 - 1.1e-82 277.5 0.0 1.2e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EPY51028.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) PsaD PF02531.11 EPY51028.1 - 0.04 13.1 0.0 5.4 6.2 0.0 2.7 3 0 0 3 3 3 0 PsaD dCMP_cyt_deam_1 PF00383.17 EPY51029.1 - 3.2e-10 39.5 0.7 5.5e-10 38.8 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EPY51029.1 - 0.29 11.0 2.3 0.81 9.5 1.0 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase Clathrin PF00637.15 EPY51030.1 - 1.2e-14 54.1 0.1 1.2e-14 54.1 0.1 3.2 3 1 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 EPY51030.1 - 0.00071 19.3 0.5 0.09 12.6 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EPY51030.1 - 0.009 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Clat_adaptor_s PF01217.15 EPY51031.1 - 5.8e-53 178.4 1.4 7.6e-53 178.0 1.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3610 PF12272.3 EPY51031.1 - 0.11 12.1 0.3 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) MinE PF03776.9 EPY51031.1 - 0.2 11.2 2.2 0.85 9.1 0.2 2.4 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE Pkinase PF00069.20 EPY51032.1 - 3.4e-08 32.9 0.0 4.7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EPY51032.1 - 1.5e-07 30.9 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EPY51032.1 - 1.9e-07 30.3 0.0 6.9e-07 28.5 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EPY51032.1 - 1.3e-05 24.5 0.0 4.9e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EPY51032.1 - 4.4e-05 23.3 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EPY51032.1 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA_anti-codon PF01336.20 EPY51033.1 - 0.00023 20.9 0.1 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain GTP_cyclohydro2 PF00925.15 EPY51034.1 - 5.6e-59 198.1 0.5 3.1e-54 182.7 0.1 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Nup188 PF10487.4 EPY51035.1 - 5.8e-51 173.4 15.9 1.1e-50 172.5 11.0 1.4 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 adh_short_C2 PF13561.1 EPY51036.1 - 2e-30 106.3 0.0 2.5e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPY51036.1 - 2e-30 105.8 0.4 2.5e-30 105.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY51036.1 - 1.9e-10 40.6 0.1 2.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY51036.1 - 0.00014 21.9 0.8 0.00025 21.0 0.6 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY51036.1 - 0.0066 15.9 0.3 0.0096 15.3 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPY51036.1 - 0.017 14.2 0.1 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EPY51036.1 - 0.027 14.2 0.3 0.07 12.9 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EPY51036.1 - 0.12 12.0 0.5 0.19 11.3 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lung_7-TM_R PF06814.8 EPY51037.1 - 1.6e-05 24.0 12.3 2.6e-05 23.3 8.5 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3311 PF11755.3 EPY51037.1 - 1.4 8.5 7.1 0.47 10.0 1.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) GST_C PF00043.20 EPY51039.1 - 1.7e-11 43.9 0.1 4.1e-11 42.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPY51039.1 - 2e-08 34.0 0.0 4.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPY51039.1 - 6.5e-08 32.3 0.2 1.4e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPY51039.1 - 1.2e-06 28.6 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPY51039.1 - 2.4e-05 24.4 0.2 5.3e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPY51039.1 - 0.0027 18.1 0.0 0.0055 17.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.1 EPY51040.1 - 4.5e-24 84.7 0.0 5.8e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY51040.1 - 3.3e-23 81.9 0.0 5.2e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPY51040.1 - 1.4e-18 66.8 0.0 1.9e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EPY51040.1 - 8.5e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY51040.1 - 1.1e-13 51.2 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY51040.1 - 1.3e-13 51.1 0.0 2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY51040.1 - 6.3e-11 42.8 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPY51040.1 - 2.6e-08 33.6 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EPY51040.1 - 3.9e-08 32.8 0.0 7.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.7 EPY51040.1 - 2.8e-06 26.8 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_26 PF13659.1 EPY51040.1 - 5.3e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EPY51040.1 - 1.2e-05 24.1 0.0 1.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EPY51040.1 - 3e-05 23.1 0.0 6.5e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 EPY51040.1 - 3.4e-05 23.5 0.0 0.00033 20.3 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 EPY51040.1 - 0.00012 20.6 0.0 0.00023 19.6 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EPY51040.1 - 0.00017 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EPY51040.1 - 0.0064 15.5 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 EPY51040.1 - 0.02 13.9 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.9 EPY51040.1 - 0.034 13.2 0.1 0.078 12.1 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.7 EPY51040.1 - 0.039 12.8 0.0 0.083 11.7 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.8 EPY51040.1 - 0.039 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) V_cholerae_RfbT PF05575.6 EPY51040.1 - 0.041 12.9 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein Methyltransf_32 PF13679.1 EPY51040.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EBV-NA3 PF05009.7 EPY51041.1 - 0.01 15.1 0.3 0.012 14.8 0.2 1.0 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) ApbA PF02558.11 EPY51042.1 - 9.1e-30 103.0 0.0 1.4e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPY51042.1 - 4.4e-26 91.3 0.4 7.3e-26 90.6 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal TrkA_N PF02254.13 EPY51042.1 - 0.0002 21.3 0.0 0.00048 20.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EPY51042.1 - 0.0018 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EPY51042.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Prok-RING_2 PF14445.1 EPY51042.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Saccharop_dh PF03435.13 EPY51042.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Malic_M PF03949.10 EPY51043.1 - 1.4e-81 273.7 0.0 2e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EPY51043.1 - 7.3e-60 201.6 0.0 1.2e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NAD_binding_9 PF13454.1 EPY51043.1 - 0.055 13.2 0.1 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EPY51043.1 - 0.21 11.6 0.5 1 9.4 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1029 PF06269.7 EPY51044.1 - 0.045 13.7 0.4 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) Cir_Bir_Yir PF06022.6 EPY51044.1 - 2.4 7.3 8.7 1.4 8.0 4.6 1.7 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Zn_clus PF00172.13 EPY51045.1 - 8.2e-10 38.4 11.7 1.8e-09 37.3 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EPY51046.1 - 1.6e-60 204.8 44.5 2.1e-60 204.4 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPY51046.1 - 1.5e-19 69.7 36.4 1.9e-19 69.3 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_31 PF01055.21 EPY51047.1 - 3.9e-162 540.0 6.9 5e-162 539.7 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AA_permease PF00324.16 EPY51048.1 - 5.8e-126 420.6 48.8 6.6e-126 420.4 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY51048.1 - 1.3e-33 116.2 52.0 1.7e-33 115.7 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease Con-6 PF10346.4 EPY51049.1 - 1.1e-26 91.9 2.8 2.6e-14 52.3 0.0 3.1 3 0 0 3 3 3 3 Conidiation protein 6 Ish1 PF10281.4 EPY51049.1 - 0.096 12.7 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Con-6 PF10346.4 EPY51050.1 - 2e-38 129.4 5.3 1e-18 66.4 0.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 MEF2_binding PF09047.5 EPY51050.1 - 0.031 13.9 0.4 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 MEF2 binding Aldedh PF00171.17 EPY51051.1 - 5.2e-175 582.2 0.4 6.1e-175 581.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPY51051.1 - 9.1e-07 27.9 0.0 1.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Oxidored_FMN PF00724.15 EPY51052.1 - 5.6e-111 370.8 0.0 6.4e-111 370.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GalP_UDP_transf PF01087.17 EPY51053.1 - 2.7e-65 219.8 0.2 4.1e-65 219.2 0.2 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EPY51053.1 - 7.1e-61 204.6 0.1 2e-60 203.1 0.0 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.3 EPY51053.1 - 0.0048 17.1 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EPY51053.1 - 0.01 16.3 0.0 0.035 14.6 0.0 1.9 2 0 0 2 2 2 0 HIT domain Epimerase PF01370.16 EPY51054.1 - 3.6e-44 150.9 0.0 4.4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPY51054.1 - 3.5e-14 52.3 0.0 7.5e-14 51.2 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPY51054.1 - 8.7e-07 28.1 0.0 2.8e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPY51054.1 - 0.0004 19.3 0.0 0.0021 17.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPY51054.1 - 0.018 13.7 0.2 0.22 10.1 0.2 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3677 PF12432.3 EPY51054.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) adh_short PF00106.20 EPY51054.1 - 0.19 11.6 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Aldose_epim PF01263.15 EPY51055.1 - 1.5e-60 204.8 0.0 2e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 EPY51055.1 - 7.5e-48 163.0 0.0 9.7e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPY51055.1 - 8.4e-22 76.8 0.1 1.7e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EPY51055.1 - 3e-15 55.6 0.0 5.6e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPY51055.1 - 1e-14 54.1 0.0 3.1e-13 49.3 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPY51055.1 - 3.6e-11 42.4 0.0 6.3e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EPY51055.1 - 2.1e-08 34.2 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EPY51055.1 - 5.3e-08 32.0 0.0 1.3e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EPY51055.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY51055.1 - 3.2e-05 24.0 0.0 5.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EPY51055.1 - 0.009 15.4 0.2 0.035 13.4 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.8 EPY51055.1 - 0.084 12.1 0.1 0.2 10.8 0.1 1.7 1 0 0 1 1 1 0 NmrA-like family GalKase_gal_bdg PF10509.4 EPY51056.1 - 1.9e-20 71.8 0.0 3.9e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EPY51056.1 - 5e-17 61.7 0.2 5e-17 61.7 0.1 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPY51056.1 - 1.4e-12 47.5 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Zn_clus PF00172.13 EPY51057.1 - 1.1e-07 31.6 13.1 2.5e-07 30.4 9.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Reticulon PF02453.12 EPY51057.1 - 0.01 15.4 1.1 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Reticulon MFS_1 PF07690.11 EPY51058.1 - 2.6e-34 118.4 33.1 2.6e-34 118.4 22.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EPY51059.1 - 3.5e-32 111.5 31.3 3.5e-32 111.5 21.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPY51059.1 - 0.00021 19.6 3.5 0.00042 18.6 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 EPY51059.1 - 0.018 15.4 0.2 0.066 13.6 0.1 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3430 PF11912.3 EPY51060.1 - 1.1e-05 25.3 1.0 1.3e-05 25.1 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EPY51060.1 - 0.02 14.9 0.3 0.034 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) DIM PF08194.7 EPY51060.1 - 0.031 14.2 1.1 0.055 13.4 0.8 1.4 1 0 0 1 1 1 0 DIM protein WWbp PF10349.4 EPY51061.1 - 4.1e-11 43.7 0.0 7.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EPY51061.1 - 3.4e-06 26.7 0.0 6.6e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EPY51061.1 - 6.6e-05 22.3 0.1 0.00013 21.3 0.1 1.5 1 1 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 EPY51061.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain F-box-like PF12937.2 EPY51062.1 - 0.012 15.3 0.8 0.036 13.7 0.5 1.9 1 0 0 1 1 1 0 F-box-like FYVE PF01363.16 EPY51062.1 - 0.25 11.2 6.2 0.66 9.9 4.3 1.7 1 0 0 1 1 1 0 FYVE zinc finger Pkinase PF00069.20 EPY51063.1 - 1.4e-55 188.3 0.0 2.1e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51063.1 - 1.8e-25 89.4 0.0 3e-23 82.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPY51063.1 - 5.6e-05 22.2 0.0 0.00017 20.6 0.0 1.6 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EPY51063.1 - 0.00046 19.5 0.1 0.00097 18.5 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EPY51063.1 - 0.0029 16.7 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GARS_N PF02844.10 EPY51063.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain APH PF01636.18 EPY51063.1 - 0.11 12.2 0.0 0.57 9.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family ParBc PF02195.13 EPY51064.1 - 5.8e-12 45.5 0.0 6.6e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain DUF1776 PF08643.5 EPY51065.1 - 5.7e-52 176.7 0.1 2.7e-48 164.6 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) A_deaminase PF00962.17 EPY51066.1 - 2.6e-116 388.1 0.0 3.7e-116 387.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Toprim PF01751.17 EPY51066.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Toprim domain ATP-synt_E PF05680.7 EPY51067.1 - 6.7e-17 61.2 0.1 7.8e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain Glyoxalase_2 PF12681.2 EPY51067.1 - 0.084 13.4 0.0 0.11 13.1 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain MUG2_C PF08593.5 EPY51068.1 - 7e-15 54.9 0.2 2.9e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Meiotically up-regulated glycoproteins C-terminal DUF3326 PF11805.3 EPY51068.1 - 0.014 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) BLOC1_2 PF10046.4 EPY51068.1 - 0.017 15.2 1.3 0.017 15.2 0.9 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.9 EPY51068.1 - 0.067 13.1 3.7 0.093 12.6 2.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Amidase PF01425.16 EPY51069.1 - 9.6e-103 344.3 0.0 1.1e-102 344.1 0.0 1.0 1 0 0 1 1 1 1 Amidase GatB_N PF02934.10 EPY51070.1 - 1.1e-68 231.1 0.0 1.4e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain DUF1279 PF06916.8 EPY51071.1 - 7e-28 96.7 0.0 8.8e-28 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Cpn60_TCP1 PF00118.19 EPY51072.1 - 3.2e-140 467.9 13.3 3.6e-140 467.8 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Apc1 PF12859.2 EPY51073.1 - 1.5e-12 47.6 0.3 1.2e-11 44.7 0.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EPY51073.1 - 0.0099 16.0 11.4 0.16 12.3 0.3 4.8 7 0 0 7 7 7 2 Proteasome/cyclosome repeat Pkinase PF00069.20 EPY51074.1 - 1.2e-65 221.3 0.0 1.8e-65 220.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51074.1 - 5.5e-34 117.3 0.0 8.5e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51074.1 - 6.1e-05 22.1 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPY51074.1 - 0.0053 16.5 0.1 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPY51074.1 - 0.0081 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 POX PF07526.6 EPY51074.1 - 5.3 7.2 10.5 0.34 11.1 1.7 2.4 2 1 1 3 3 3 0 Associated with HOX PAF-AH_p_II PF03403.8 EPY51075.1 - 3e-93 312.1 0.0 6.8e-92 307.6 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EPY51075.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EPY51075.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RRM_1 PF00076.17 EPY51076.1 - 1.2e-10 40.8 0.0 5.8e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51076.1 - 6e-08 32.5 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51076.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPY51076.1 - 0.1 13.0 0.0 0.1 13.0 0.0 3.3 3 1 1 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 CLTH PF10607.4 EPY51077.1 - 4.3e-30 104.3 1.4 4.3e-30 104.3 1.0 1.9 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPY51077.1 - 3.6e-07 29.7 0.0 1e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 LisH SDA1 PF05285.7 EPY51078.1 - 5.2e-81 272.4 23.5 5.2e-81 272.4 16.3 2.6 2 1 1 3 3 3 1 SDA1 NUC130_3NT PF08158.7 EPY51078.1 - 2.2e-17 63.0 0.3 6.6e-17 61.5 0.2 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Tau95 PF09734.4 EPY51078.1 - 0.0076 15.6 0.9 0.0076 15.6 0.6 2.0 1 1 1 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit NUDIX PF00293.23 EPY51079.1 - 2.3e-27 95.2 0.0 3.4e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain RRM_6 PF14259.1 EPY51080.1 - 1.6e-27 95.2 0.5 5.2e-09 35.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY51080.1 - 6.5e-20 70.5 2.7 1.1e-09 37.8 0.1 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51080.1 - 4.6e-18 64.7 0.7 5.1e-07 29.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY51080.1 - 0.00051 19.7 0.3 0.49 10.2 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPY51080.1 - 0.066 13.0 0.4 0.82 9.5 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif Proteasome PF00227.21 EPY51081.1 - 2.8e-57 193.1 0.0 3.4e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPY51081.1 - 4.9e-12 44.9 0.0 9.4e-12 44.0 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Abhydrolase_1 PF00561.15 EPY51082.1 - 2.6e-23 82.8 0.0 4.8e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPY51082.1 - 9.3e-08 32.2 0.0 7.9e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L23eN PF03939.8 EPY51083.1 - 2.6e-20 72.1 11.5 5.2e-20 71.2 8.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EPY51083.1 - 5.6e-18 64.6 0.9 1.2e-17 63.6 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 RHH_4 PF13467.1 EPY51084.1 - 0.08 12.8 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain Exo70 PF03081.10 EPY51085.1 - 1.3e-44 152.5 6.8 1.3e-44 152.5 4.7 2.2 2 1 0 2 2 2 1 Exo70 exocyst complex subunit DUF4241 PF14025.1 EPY51085.1 - 0.2 11.4 2.2 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) Cyclin_N PF00134.18 EPY51086.1 - 1e-45 154.4 0.1 3.6e-45 152.6 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPY51086.1 - 2.1e-32 111.4 0.0 4.3e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain BRCT PF00533.21 EPY51088.1 - 4.7e-33 113.1 11.0 8.9e-10 38.5 0.0 6.6 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPY51088.1 - 1e-22 79.7 4.5 3.7e-14 52.3 0.3 4.7 5 0 0 5 5 5 3 twin BRCT domain PAPS_reduct PF01507.14 EPY51089.1 - 1.7 8.4 5.8 0.46 10.2 1.9 1.7 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family DUF1664 PF07889.7 EPY51089.1 - 3 7.6 8.9 23 4.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RPN7 PF10602.4 EPY51090.1 - 1.5e-47 161.2 1.0 2.8e-47 160.3 0.7 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EPY51090.1 - 1.7e-17 63.6 0.4 7.4e-17 61.5 0.0 2.3 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EPY51090.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HTH_DeoR PF08220.7 EPY51090.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TMCO5 PF14992.1 EPY51090.1 - 0.51 9.4 4.0 0.12 11.4 0.6 1.5 2 0 0 2 2 2 0 TMCO5 family Aminotran_1_2 PF00155.16 EPY51091.1 - 1.4e-34 119.6 0.0 1.9e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PEX11 PF05648.9 EPY51092.1 - 1.5e-50 171.5 3.4 1.7e-50 171.3 2.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SNF2_N PF00176.18 EPY51093.1 - 4.4e-81 271.9 2.1 6e-81 271.5 1.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY51093.1 - 1.9e-10 40.4 0.0 7.3e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY51093.1 - 6.3e-07 29.4 0.4 3.8e-06 26.8 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Nup84_Nup100 PF04121.8 EPY51094.1 - 4.3e-165 550.2 2.3 5.5e-165 549.9 1.6 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Aminotran_4 PF01063.14 EPY51095.1 - 3.7e-26 92.0 0.0 7.3e-26 91.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class IV DUF2967 PF11179.3 EPY51095.1 - 0.14 11.6 0.8 0.23 10.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Apq12 PF12716.2 EPY51096.1 - 4.5e-13 48.6 11.9 4.5e-13 48.6 8.3 1.5 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Tmemb_cc2 PF10267.4 EPY51096.1 - 0.12 10.9 1.3 0.13 10.7 0.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3671 PF12420.3 EPY51096.1 - 0.22 11.5 1.4 0.29 11.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function PFL PF02901.10 EPY51097.1 - 0.064 11.6 0.1 0.068 11.5 0.0 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase UPF0054 PF02130.12 EPY51097.1 - 0.1 11.8 0.1 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 Arginosuc_synth PF00764.14 EPY51098.1 - 1.6e-147 491.6 0.0 1.8e-147 491.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EPY51098.1 - 0.0041 16.4 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Glyco_hydro_114 PF03537.8 EPY51098.1 - 0.13 12.0 0.2 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 RXT2_N PF08595.6 EPY51099.1 - 8.5e-22 77.5 5.7 5.7e-21 74.8 1.8 2.5 2 1 0 2 2 2 1 RXT2-like, N-terminal DUF2296 PF10058.4 EPY51099.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) SET PF00856.23 EPY51100.1 - 2.3e-26 93.0 0.2 2.3e-26 93.0 0.1 3.1 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.11 EPY51100.1 - 4e-21 75.2 5.5 4e-21 75.2 3.8 2.9 3 0 0 3 3 3 1 Pre-SET motif Chromo PF00385.19 EPY51100.1 - 1.8e-12 46.7 1.4 3.1e-12 45.9 1.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PH_6 PF15406.1 EPY51101.1 - 6.6e-21 74.4 2.5 1.6e-19 70.0 0.0 3.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EPY51101.1 - 0.0004 20.5 0.0 0.0036 17.4 0.0 2.6 1 1 0 1 1 1 1 PH domain Glyoxalase_2 PF12681.2 EPY51105.1 - 7.5e-10 39.3 0.0 8.9e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPY51105.1 - 4.4e-07 29.9 0.0 3.5e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cys_Met_Meta_PP PF01053.15 EPY51106.1 - 9.2e-153 508.1 0.0 1e-152 507.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EPY51106.1 - 2e-12 46.8 0.1 1.9e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EPY51106.1 - 2.3e-11 43.2 0.0 3.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPY51106.1 - 7.8e-07 28.1 0.1 1.2e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EPY51106.1 - 0.0003 19.2 0.1 0.00049 18.5 0.1 1.4 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EPY51106.1 - 0.00085 18.5 0.0 0.0047 16.1 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EPY51106.1 - 0.0046 15.4 0.0 0.0071 14.8 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EPY51106.1 - 0.0067 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein LT-IIB PF06453.6 EPY51106.1 - 0.06 13.0 0.1 0.19 11.4 0.0 1.8 1 1 1 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) RRM_1 PF00076.17 EPY51107.1 - 2.8e-16 58.9 0.1 3.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51107.1 - 8.2e-13 48.1 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51107.1 - 1.5e-10 40.7 0.0 2.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY51107.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Mob1_phocein PF03637.12 EPY51108.1 - 3.9e-76 254.6 1.2 4.5e-76 254.3 0.8 1.0 1 0 0 1 1 1 1 Mob1/phocein family Acyltransferase PF01553.16 EPY51109.1 - 9.3e-25 86.5 0.0 1.8e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MMR_HSR1_C PF08438.5 EPY51110.1 - 4.2e-30 104.1 0.0 6.3e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EPY51110.1 - 1.5e-17 63.6 0.0 2.8e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY51110.1 - 8.3e-09 34.9 0.0 5.9e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPY51110.1 - 0.0019 18.0 0.1 0.0088 15.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 EPY51110.1 - 0.0043 16.6 0.2 2.3 7.6 0.1 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein ArgK PF03308.11 EPY51110.1 - 0.0063 15.3 0.1 0.012 14.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein GTP_EFTU PF00009.22 EPY51110.1 - 0.01 15.2 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EPY51110.1 - 0.034 13.6 0.7 0.26 10.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EPY51110.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPY51110.1 - 0.12 12.6 0.7 0.24 11.7 0.0 1.8 2 0 0 2 2 1 0 ABC transporter KTI12 PF08433.5 EPY51110.1 - 0.18 10.9 0.0 0.45 9.6 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ras PF00071.17 EPY51111.1 - 2.8e-48 163.3 0.7 3.2e-48 163.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY51111.1 - 2.1e-16 60.4 0.3 2.9e-16 60.0 0.2 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY51111.1 - 2.8e-08 33.1 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPY51111.1 - 7.2e-07 28.8 0.1 7.4e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY51111.1 - 5.2e-06 26.4 0.1 8.2e-06 25.7 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPY51111.1 - 1.4e-05 24.3 0.1 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EPY51111.1 - 0.0026 17.5 0.6 0.0058 16.3 0.4 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EPY51111.1 - 0.019 14.8 0.1 0.024 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF3533 PF12051.3 EPY51111.1 - 0.099 11.3 0.6 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) WAPL PF07814.8 EPY51112.1 - 5.8e-28 97.6 11.5 1.1e-26 93.3 8.0 2.2 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin XPA_C PF05181.7 EPY51114.1 - 5.3e-29 99.5 1.2 1.5e-28 98.1 0.8 1.9 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EPY51114.1 - 1.3e-10 40.7 5.1 2.2e-10 40.0 3.6 1.4 1 0 0 1 1 1 1 XPA protein N-terminal Vma12 PF11712.3 EPY51114.1 - 7.2 6.3 9.4 0.2 11.3 1.5 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SOG2 PF10428.4 EPY51115.1 - 8.6e-56 189.4 15.0 7.8e-35 120.3 0.2 3.2 2 1 1 3 3 3 2 RAM signalling pathway protein LRR_4 PF12799.2 EPY51115.1 - 1.2e-18 66.3 13.1 5e-07 29.1 0.7 4.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPY51115.1 - 2.6e-17 62.3 14.8 7.1e-11 41.6 1.4 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EPY51115.1 - 1.3e-05 24.5 21.4 0.065 13.2 0.0 7.3 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 EPY51115.1 - 2.9e-05 23.5 0.6 2.6 8.6 0.0 5.8 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EPY51115.1 - 0.054 13.5 4.4 19 5.7 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat PA_decarbox PF05870.6 EPY51115.1 - 0.2 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Ribosomal_L14 PF00238.14 EPY51117.1 - 2e-43 147.0 1.5 2.2e-43 146.8 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DDE_1 PF03184.14 EPY51118.1 - 3.4e-58 196.3 0.4 5.5e-58 195.6 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPY51118.1 - 1.1e-13 50.7 0.0 3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PX PF00787.19 EPY51119.1 - 6.9e-27 93.4 0.2 8.2e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 PX domain RRM_1 PF00076.17 EPY51120.1 - 1.1e-18 66.6 0.1 1.7e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51120.1 - 1.6e-10 40.7 0.0 3.6e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51120.1 - 6.2e-05 22.7 0.0 9.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPY51121.1 - 3.3e-43 144.0 23.2 8.4e-10 38.1 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 EPY51121.1 - 3.5e-41 139.8 2.3 6.8e-41 138.9 1.6 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EPY51121.1 - 2.5e-39 134.6 5.6 3.6e-39 134.1 3.9 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EPY51121.1 - 9.9e-08 31.7 0.0 0.00039 20.1 0.0 3.3 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DREV PF05219.7 EPY51121.1 - 0.023 13.5 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase HEAT_EZ PF13513.1 EPY51121.1 - 5.2 7.6 6.5 42 4.8 0.2 3.5 3 1 0 3 3 3 0 HEAT-like repeat Voltage_CLC PF00654.15 EPY51122.1 - 1.9e-79 267.3 29.6 6.9e-78 262.1 19.6 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EPY51122.1 - 0.009 15.7 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 CBS domain Voltage_CLC PF00654.15 EPY51123.1 - 7.6e-78 262.0 28.3 7.6e-78 262.0 19.6 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EPY51123.1 - 0.0097 15.6 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 CBS domain CBF PF03914.12 EPY51124.1 - 1.5e-28 99.3 1.1 1.5e-28 99.3 0.7 3.3 4 0 0 4 4 4 1 CBF/Mak21 family NOC3p PF07540.6 EPY51124.1 - 2.1e-27 95.2 0.4 2.1e-27 95.2 0.3 2.7 3 0 0 3 3 3 1 Nucleolar complex-associated protein Clat_adaptor_s PF01217.15 EPY51125.1 - 2.4e-54 182.9 1.9 2.6e-54 182.8 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PIG-H PF10181.4 EPY51126.1 - 2e-20 72.1 0.0 3.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Ribosomal_S2 PF00318.15 EPY51127.1 - 9.8e-43 145.8 0.1 1.8e-20 73.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_L27e PF01777.13 EPY51128.1 - 2.5e-38 130.0 3.3 3.3e-38 129.6 2.3 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EPY51128.1 - 0.036 13.7 1.5 0.038 13.7 0.1 1.9 2 0 0 2 2 2 0 KOW motif Glu_cys_ligase PF04262.9 EPY51129.1 - 0.11 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase ORC2 PF04084.9 EPY51130.1 - 5.8e-92 307.9 2.3 7.3e-92 307.6 1.6 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 RhoGAP PF00620.22 EPY51130.1 - 0.029 14.0 0.3 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain Exo_endo_phos PF03372.18 EPY51131.1 - 1.5e-18 67.6 0.3 1.9e-18 67.3 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4231 PF14015.1 EPY51131.1 - 0.11 12.4 0.6 0.21 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) WD40 PF00400.27 EPY51132.1 - 4.8e-31 105.5 8.7 1.8e-06 27.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPY51132.1 - 0.0002 21.1 0.1 0.022 14.4 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.1 EPY51132.1 - 0.00033 20.6 0.1 0.18 12.0 0.0 4.2 5 0 0 5 5 5 1 Kelch motif DUF1513 PF07433.6 EPY51132.1 - 0.071 11.9 0.2 1.1 8.0 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 EPY51132.1 - 0.14 10.8 0.4 7.2 5.2 0.1 2.3 1 1 0 2 2 2 0 Nup133 N terminal like Gemin7 PF11095.3 EPY51133.1 - 2.1e-14 53.0 0.0 2.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) GSHPx PF00255.14 EPY51134.1 - 2.9e-43 145.6 0.1 3.8e-43 145.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EPY51134.1 - 1.6e-06 27.7 0.0 3.1e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPY51134.1 - 1.2e-05 24.8 0.0 3.7e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 EPY51134.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Adaptin_N PF01602.15 EPY51135.1 - 1.2e-120 403.3 11.9 1.5e-120 403.0 8.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EPY51135.1 - 5.9e-18 65.2 0.0 1.4e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EPY51135.1 - 0.00096 19.3 1.4 3.1 8.1 0.0 4.4 3 2 3 6 6 6 2 HEAT repeats Cnd1 PF12717.2 EPY51135.1 - 1.3 8.8 7.2 0.96 9.2 0.8 2.8 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 cwf18 PF08315.7 EPY51136.1 - 5.3e-31 107.7 9.1 5.3e-31 107.7 6.3 1.8 1 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor Ribosomal_S8e PF01201.17 EPY51137.1 - 2.8e-36 124.5 9.8 2.3e-35 121.6 6.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 EPY51137.1 - 2.5 7.3 8.6 0.44 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Ribosomal_60s PF00428.14 EPY51138.1 - 1.7e-24 86.0 7.9 3e-24 85.2 5.5 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2624 PF11116.3 EPY51138.1 - 0.039 14.4 0.0 1.9 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Ank_2 PF12796.2 EPY51139.1 - 1.6e-15 57.1 0.2 2.4e-13 50.2 0.1 3.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPY51139.1 - 3.1e-14 52.6 0.0 3.7e-12 46.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPY51139.1 - 8.9e-14 51.5 0.1 6.1e-09 36.1 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EPY51139.1 - 8e-13 47.4 0.4 2.7e-08 33.2 0.1 4.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EPY51139.1 - 5e-10 38.6 0.1 2.5e-06 27.2 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeat CPL PF08144.6 EPY51140.1 - 2.1e-26 92.5 0.5 2.1e-25 89.3 0.0 2.9 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 EPY51140.1 - 5.8e-06 25.4 0.2 12 5.5 0.0 5.6 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DUF2890 PF11081.3 EPY51140.1 - 0.0086 16.1 16.0 0.017 15.1 11.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) ADP_ribosyl_GH PF03747.9 EPY51140.1 - 0.079 12.7 0.0 0.079 12.7 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Formyl_trans_N PF00551.14 EPY51141.1 - 2.7e-44 150.8 0.1 3.2e-44 150.6 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase Spore_YtrH PF14034.1 EPY51141.1 - 0.087 12.7 0.2 2.7 7.9 0.0 2.5 3 0 0 3 3 3 0 Sporulation protein YtrH Ham1p_like PF01725.11 EPY51144.1 - 4.5e-50 169.6 0.0 5e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family RNase_P_Rpp14 PF01900.14 EPY51145.1 - 1.2e-37 128.0 0.0 1.4e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family TB2_DP1_HVA22 PF03134.14 EPY51146.1 - 6.4e-30 102.7 8.6 9.4e-30 102.2 6.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Na_K-ATPase PF00287.13 EPY51146.1 - 0.15 10.7 2.7 0.24 10.1 1.9 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain CTDII PF01556.13 EPY51147.1 - 4.4e-25 87.3 0.3 9e-21 73.5 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EPY51147.1 - 4.8e-25 87.0 2.6 7.6e-25 86.4 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain EF-hand_1 PF00036.27 EPY51148.1 - 1.6e-25 86.4 9.2 6.5e-07 28.1 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPY51148.1 - 5.1e-22 77.7 2.4 7.6e-12 45.1 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPY51148.1 - 6.9e-21 72.6 8.7 2.7e-06 26.4 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EPY51148.1 - 7.9e-21 72.0 4.8 4.6e-05 22.9 0.2 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EPY51148.1 - 1.6e-15 56.4 12.7 1.5e-05 24.4 0.6 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EPY51148.1 - 1.4e-07 31.5 0.1 0.0078 16.2 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EPY51148.1 - 3.3e-05 23.5 5.2 0.31 10.7 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPY51148.1 - 0.0092 15.8 0.0 0.74 9.7 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain NLE PF08154.7 EPY51148.1 - 0.051 13.6 0.1 14 5.7 0.0 2.3 2 0 0 2 2 2 0 NLE (NUC135) domain DNA_Packaging PF11053.3 EPY51148.1 - 0.071 12.7 0.1 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 Terminase DNA packaging enzyme EPL1 PF10513.4 EPY51149.1 - 2.8e-27 95.9 1.8 5.9e-27 94.8 1.2 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like Clp1 PF06807.9 EPY51150.1 - 8.6e-09 35.4 0.0 3.8e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPY51150.1 - 3.4e-05 23.5 0.0 6.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EPY51150.1 - 0.0022 18.1 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPY51150.1 - 0.0032 18.2 0.0 0.0074 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EPY51150.1 - 0.0037 16.7 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 EPY51150.1 - 0.017 13.9 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 EPY51150.1 - 0.034 14.4 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPY51150.1 - 0.049 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 EPY51150.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EPY51150.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EPY51150.1 - 0.092 12.6 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPY51150.1 - 0.1 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPY51150.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EPY51150.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY51150.1 - 0.14 11.9 0.1 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EPY51150.1 - 0.16 10.6 0.1 0.26 9.9 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Ribosomal_L30 PF00327.15 EPY51151.1 - 1.3e-10 40.7 0.0 1.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CCDC66 PF15236.1 EPY51152.1 - 0.11 12.1 9.1 0.2 11.2 6.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 eIF-6 PF01912.13 EPY51153.1 - 1.9e-84 281.7 1.0 2.3e-84 281.4 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family Myosin_head PF00063.16 EPY51154.1 - 7.4e-237 787.7 8.1 7.4e-237 787.7 5.6 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EPY51154.1 - 5.4e-20 71.2 2.4 2.4e-19 69.1 1.6 2.2 1 0 0 1 1 1 1 DIL domain AAA_22 PF13401.1 EPY51154.1 - 0.00015 21.9 0.2 0.0014 18.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.14 EPY51154.1 - 0.00035 20.1 0.0 0.00088 18.9 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.22 EPY51154.1 - 0.00095 18.6 5.1 0.28 10.9 0.1 3.9 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF258 PF03193.11 EPY51154.1 - 0.0052 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 BAR PF03114.13 EPY51155.1 - 4.7e-30 104.7 1.9 8.3e-30 103.9 1.3 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EPY51155.1 - 7.7e-09 34.8 0.0 1.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPY51155.1 - 6.1e-08 32.1 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPY51155.1 - 5.1e-05 22.6 0.0 9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M28 PF04389.12 EPY51156.1 - 3.9e-33 114.6 0.0 9.4e-33 113.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPY51156.1 - 0.001 18.6 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Palm_thioest PF02089.10 EPY51156.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase NPCC PF08058.6 EPY51156.1 - 0.14 11.9 2.2 0.9 9.3 0.3 3.2 1 1 1 2 2 2 0 Nuclear pore complex component zf-C3H1 PF10650.4 EPY51156.1 - 2.7 7.5 5.2 0.48 9.9 1.0 1.7 2 0 0 2 2 2 0 Putative zinc-finger domain DUF2431 PF10354.4 EPY51157.1 - 3.8e-54 183.1 0.2 5.2e-54 182.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) MTS PF05175.9 EPY51157.1 - 0.00073 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain SpecificRecomb PF10136.4 EPY51157.1 - 0.026 12.6 0.0 0.033 12.2 0.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase Methyltransf_26 PF13659.1 EPY51157.1 - 0.049 13.6 0.0 0.085 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.26 EPY51158.1 - 2.8e-06 27.2 0.1 7.9e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vps39_2 PF10367.4 EPY51158.1 - 0.095 12.8 0.2 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF1974 PF09317.6 EPY51158.1 - 0.68 9.2 0.0 0.68 9.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1974) BRE1 PF08647.6 EPY51159.1 - 2e-15 56.5 1.9 2e-15 56.5 1.3 5.6 3 2 1 5 5 3 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 EPY51159.1 - 9.6e-07 28.3 6.3 1.7e-06 27.6 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY51159.1 - 3.2e-06 27.0 9.2 5.6e-06 26.2 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY51159.1 - 8.8e-06 25.4 8.1 1.6e-05 24.6 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPY51159.1 - 2.2e-05 24.0 8.5 4.4e-05 23.0 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY51159.1 - 2.3e-05 23.9 7.3 4.7e-05 23.0 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPY51159.1 - 0.0019 17.8 3.7 0.0036 16.9 1.7 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EPY51159.1 - 0.0024 17.9 3.2 0.0055 16.7 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EPY51159.1 - 0.011 15.3 3.9 0.028 14.0 2.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HalX PF08663.5 EPY51159.1 - 0.018 15.0 19.2 0.19 11.7 0.3 5.8 4 2 1 5 5 5 0 HalX domain zf-C3HC4_4 PF15227.1 EPY51159.1 - 0.018 14.8 4.9 0.018 14.8 3.4 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.1 EPY51159.1 - 0.14 11.9 0.9 0.32 10.7 0.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Guanylin PF02058.10 EPY51159.1 - 0.17 11.9 5.7 0.11 12.5 1.4 2.7 2 0 0 2 2 2 0 Guanylin precursor zf-RING_6 PF14835.1 EPY51159.1 - 0.17 11.6 2.2 0.35 10.6 1.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EPY51159.1 - 0.93 9.0 4.6 2.7 7.5 3.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 UPF0547 PF10571.4 EPY51159.1 - 3.9 7.2 5.6 7.3 6.3 0.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Pox_A_type_inc PF04508.7 EPY51159.1 - 9.8 6.2 12.7 0.19 11.5 1.1 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Pep3_Vps18 PF05131.9 EPY51160.1 - 3e-28 98.1 4.7 1.3e-27 95.9 0.4 2.9 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 EPY51160.1 - 2.1e-07 31.1 1.7 5.8e-07 29.6 1.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 EPY51160.1 - 0.0018 18.2 7.9 0.0044 17.0 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) bPH_3 PF14470.1 EPY51160.1 - 0.003 17.8 1.2 3.5 7.9 0.0 3.4 4 0 0 4 4 4 2 Bacterial PH domain TPR_12 PF13424.1 EPY51160.1 - 0.01 15.7 1.5 2.7 7.9 0.0 3.7 3 2 0 3 3 3 1 Tetratricopeptide repeat zf-RING_5 PF14634.1 EPY51160.1 - 0.023 14.4 7.1 0.072 12.8 4.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EPY51160.1 - 0.046 13.5 11.6 0.018 14.8 6.0 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 EPY51160.1 - 0.36 10.5 7.9 1 9.0 5.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rhomboid PF01694.17 EPY51161.1 - 1.1e-19 70.8 12.0 1.6e-19 70.3 8.3 1.2 1 0 0 1 1 1 1 Rhomboid family DUF2663 PF10864.3 EPY51161.1 - 0.53 10.4 3.6 0.7 10.1 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) Mog1 PF04603.7 EPY51162.1 - 9.2e-47 158.5 0.4 1.3e-46 158.0 0.3 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Glucan_synthase PF02364.10 EPY51163.1 - 0 1469.9 0.0 0 1469.2 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPY51163.1 - 8.5e-34 115.9 0.2 2.1e-33 114.6 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 HEAT_2 PF13646.1 EPY51164.1 - 1.1e-25 89.6 15.7 6.7e-11 42.3 0.3 7.7 5 2 4 10 10 10 6 HEAT repeats HEAT PF02985.17 EPY51164.1 - 1.4e-24 83.9 15.4 0.00012 21.8 0.0 12.2 12 0 0 12 12 12 6 HEAT repeat HEAT_EZ PF13513.1 EPY51164.1 - 6.4e-20 71.0 28.4 1.4e-07 31.8 0.2 10.8 11 1 1 12 12 11 6 HEAT-like repeat RIX1 PF08167.7 EPY51164.1 - 2.6e-11 43.4 0.0 0.0041 16.8 0.0 5.4 5 1 1 6 6 6 3 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 EPY51164.1 - 1.4e-10 41.4 1.6 0.0018 18.6 0.0 5.7 4 2 3 7 7 6 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EPY51164.1 - 2.2e-05 24.1 5.5 0.87 9.5 0.0 6.9 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EPY51164.1 - 4.6e-05 22.8 0.9 0.12 11.6 0.0 4.5 3 1 1 4 4 4 1 CLASP N terminal Xpo1 PF08389.7 EPY51164.1 - 7.7e-05 22.6 0.1 1.2 9.0 0.0 5.6 5 1 0 5 5 5 1 Exportin 1-like protein DUF4042 PF13251.1 EPY51164.1 - 0.00034 20.1 0.7 2 7.8 0.0 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.4 EPY51164.1 - 0.00036 18.9 0.2 0.072 11.3 0.0 3.9 3 2 2 5 5 5 1 Proteasome non-ATPase 26S subunit DUF2435 PF10363.4 EPY51164.1 - 0.014 15.2 0.7 0.67 9.8 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) DUF445 PF04286.7 EPY51164.1 - 0.021 14.3 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DNA_alkylation PF08713.6 EPY51164.1 - 0.025 14.1 0.2 0.51 9.8 0.0 2.5 2 0 0 2 2 2 0 DNA alkylation repair enzyme Peptidase_C14 PF00656.17 EPY51165.1 - 2.1e-66 224.1 0.0 2.8e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain PGM_PMM_I PF02878.11 EPY51166.1 - 8.3e-42 141.9 0.1 1.4e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EPY51166.1 - 6.8e-19 68.1 0.0 1.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EPY51166.1 - 8.7e-13 48.3 0.1 1.6e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EPY51166.1 - 1.6e-05 24.8 0.0 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNA_pol_Rpb5_C PF01191.14 EPY51166.1 - 0.15 11.6 0.2 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain OSCP PF00213.13 EPY51167.1 - 1.9e-44 151.5 0.5 2.2e-44 151.3 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DNA_pol3_a_NI PF14480.1 EPY51167.1 - 0.028 14.0 0.1 8 6.1 0.0 2.6 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus I Metallophos PF00149.23 EPY51168.1 - 7.9e-12 44.9 1.3 2.6e-11 43.2 0.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin_6 PF13848.1 EPY51169.1 - 7.4e-08 32.3 0.2 0.0054 16.5 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 EPY51169.1 - 1.2e-05 24.9 0.0 0.0026 17.4 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin NAD_binding_10 PF13460.1 EPY51170.1 - 2.5e-11 43.8 0.0 3e-10 40.3 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY51170.1 - 1.2e-06 28.1 0.0 2.8e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY51170.1 - 0.00074 18.3 0.0 0.0044 15.7 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPY51170.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPY51170.1 - 0.014 14.3 0.0 0.57 9.0 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 EPY51170.1 - 0.018 14.2 0.0 0.49 9.6 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family GM_CSF PF01109.12 EPY51170.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor ELFV_dehydrog PF00208.16 EPY51170.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AMPKBI PF04739.10 EPY51171.1 - 3.2e-27 94.3 1.9 3.2e-27 94.3 1.3 1.9 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain FNIP PF05725.7 EPY51171.1 - 0.11 12.5 1.9 0.19 11.7 0.6 1.8 2 0 0 2 2 2 0 FNIP Repeat PIG-X PF08320.7 EPY51172.1 - 7.4e-38 129.9 1.7 5.2e-37 127.1 1.2 2.1 1 1 0 1 1 1 1 PIG-X / PBN1 Pkinase PF00069.20 EPY51173.1 - 1.1e-57 195.1 0.0 2.1e-57 194.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51173.1 - 4.9e-27 94.6 0.0 1.2e-25 90.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51173.1 - 5.7e-11 41.9 0.0 5.1e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPY51173.1 - 0.00011 22.0 0.2 0.00035 20.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPY51173.1 - 0.006 15.4 0.2 0.0089 14.8 0.2 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EPY51173.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_18 PF13238.1 EPY51174.1 - 6e-24 84.8 0.4 1.3e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPY51174.1 - 1.4e-12 48.5 0.2 1.9e-12 48.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY51174.1 - 3.1e-07 30.3 0.0 4.4e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPY51174.1 - 1.8e-05 24.7 0.0 3.8e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPY51174.1 - 3.6e-05 23.9 0.0 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 EPY51174.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EPY51174.1 - 0.00033 20.7 0.0 0.00078 19.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPY51174.1 - 0.00057 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ADK PF00406.17 EPY51174.1 - 0.0011 18.8 0.2 0.0052 16.6 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.10 EPY51174.1 - 0.0016 18.2 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.12 EPY51174.1 - 0.0017 17.8 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein MobB PF03205.9 EPY51174.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EPY51174.1 - 0.0026 16.9 0.1 0.048 12.7 0.0 2.0 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.17 EPY51174.1 - 0.003 17.7 0.0 0.0094 16.1 0.0 1.8 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EPY51174.1 - 0.0039 17.2 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.12 EPY51174.1 - 0.0041 16.5 0.1 0.84 8.9 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase FtsK_SpoIIIE PF01580.13 EPY51174.1 - 0.0043 16.5 0.0 0.0088 15.5 0.0 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.14 EPY51174.1 - 0.0051 16.2 0.0 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPY51174.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPY51174.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 EPY51174.1 - 0.0095 14.9 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 EPY51174.1 - 0.011 15.5 0.4 0.05 13.4 0.3 1.9 1 1 0 1 1 1 0 Shikimate kinase NACHT PF05729.7 EPY51174.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EPY51174.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPY51174.1 - 0.019 14.4 0.0 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPY51174.1 - 0.026 15.0 0.0 0.11 13.0 0.0 2.0 2 1 0 2 2 2 0 Miro-like protein TrwB_AAD_bind PF10412.4 EPY51174.1 - 0.029 13.0 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 EPY51174.1 - 0.029 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EPY51174.1 - 0.031 13.1 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 EPY51174.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EPY51174.1 - 0.057 13.3 0.0 0.09 12.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 EPY51174.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EPY51174.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EPY51174.1 - 0.079 12.3 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain GlpM PF06942.7 EPY51175.1 - 0.077 13.2 1.1 2 8.7 0.1 2.1 2 0 0 2 2 2 0 GlpM protein Colicin_im PF03857.8 EPY51175.1 - 4.1 7.1 8.7 1 9.1 0.4 2.2 1 1 1 2 2 2 0 Colicin immunity protein DUF1295 PF06966.7 EPY51176.1 - 0.0012 18.1 0.1 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_M41 PF01434.13 EPY51177.1 - 1.1e-70 237.3 0.4 1.8e-70 236.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPY51177.1 - 4.5e-42 143.3 0.0 8.7e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPY51177.1 - 8.5e-06 25.8 0.8 0.00016 21.6 0.6 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY51177.1 - 9e-06 25.8 0.6 0.0083 16.2 0.0 2.9 2 1 1 3 3 2 1 AAA domain AAA_17 PF13207.1 EPY51177.1 - 2.3e-05 25.1 0.0 7.4e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPY51177.1 - 2.7e-05 23.9 0.1 0.0001 22.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EPY51177.1 - 3.1e-05 22.8 0.0 5.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EPY51177.1 - 0.00016 21.3 0.1 0.00053 19.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EPY51177.1 - 0.00039 19.5 0.0 0.0008 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EPY51177.1 - 0.001 18.5 0.1 0.0049 16.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 EPY51177.1 - 0.0017 18.0 0.1 0.094 12.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 EPY51177.1 - 0.0036 16.7 2.1 0.02 14.2 0.8 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPY51177.1 - 0.0036 16.4 0.3 0.01 15.0 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EPY51177.1 - 0.0076 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPY51177.1 - 0.0078 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPY51177.1 - 0.0079 15.3 0.7 0.041 12.9 0.2 2.1 1 1 1 2 2 2 1 Zeta toxin AAA_2 PF07724.9 EPY51177.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EPY51177.1 - 0.014 15.2 0.0 0.056 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EPY51177.1 - 0.024 14.9 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EPY51177.1 - 0.034 13.0 0.0 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EPY51177.1 - 0.072 13.1 0.1 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Peptidase_M50B PF13398.1 EPY51177.1 - 0.072 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Sigma54_activat PF00158.21 EPY51177.1 - 0.081 12.3 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EPY51177.1 - 0.16 11.0 0.1 0.52 9.3 0.0 1.8 2 0 0 2 2 2 0 KaiC ATP-synt_D PF01813.12 EPY51178.1 - 4.6e-64 215.5 5.2 7.4e-64 214.9 3.6 1.3 1 0 0 1 1 1 1 ATP synthase subunit D Cob_adeno_trans PF01923.13 EPY51178.1 - 0.041 13.6 0.4 0.34 10.6 0.0 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase GAS PF13851.1 EPY51178.1 - 0.042 13.0 4.7 0.11 11.6 0.1 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding EXOSC1 PF10447.4 EPY51179.1 - 8.5e-26 89.7 2.1 1.3e-25 89.1 1.4 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EPY51179.1 - 0.091 12.0 0.1 0.23 10.7 0.1 1.7 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EPY51179.1 - 0.094 12.8 0.8 0.86 9.7 0.6 2.2 1 1 0 1 1 1 0 S1 RNA binding domain LSM PF01423.17 EPY51180.1 - 9.4e-15 53.9 0.3 9.4e-15 53.9 0.2 1.4 2 0 0 2 2 2 1 LSM domain Flag1_repress PF03614.8 EPY51180.1 - 0.14 11.6 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Lyase_1 PF00206.15 EPY51181.1 - 1.2e-42 146.2 0.0 2e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EPY51181.1 - 3.9e-20 71.6 0.1 9.6e-20 70.3 0.1 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Syntaxin PF00804.20 EPY51181.1 - 0.081 13.1 0.3 6.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Syntaxin DUF1989 PF09347.5 EPY51182.1 - 9.4e-51 171.5 0.0 1.2e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) TPR_11 PF13414.1 EPY51184.1 - 5.3e-56 186.1 26.7 1.3e-09 37.5 0.0 11.4 7 3 2 11 11 11 9 TPR repeat TPR_1 PF00515.23 EPY51184.1 - 1.8e-41 138.0 30.0 0.002 17.6 0.0 16.5 17 0 0 17 17 16 11 Tetratricopeptide repeat TPR_2 PF07719.12 EPY51184.1 - 5e-37 122.8 32.6 2.3e-05 23.9 0.0 17.4 18 0 0 18 18 17 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPY51184.1 - 2.8e-33 111.3 10.8 0.0071 16.8 0.1 16.3 12 6 6 18 18 16 6 Tetratricopeptide repeat TPR_16 PF13432.1 EPY51184.1 - 8.3e-32 109.1 15.9 6.1e-06 26.7 0.1 12.7 12 3 4 16 16 14 6 Tetratricopeptide repeat TPR_17 PF13431.1 EPY51184.1 - 4.5e-30 101.3 18.3 0.05 13.8 0.0 14.7 16 2 1 17 17 16 8 Tetratricopeptide repeat TPR_19 PF14559.1 EPY51184.1 - 6.4e-30 103.3 23.9 4.7e-07 30.0 0.1 13.0 9 4 3 13 13 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPY51184.1 - 5.1e-28 96.8 32.4 0.0034 17.2 0.1 12.6 10 3 2 12 12 12 8 Tetratricopeptide repeat TPR_8 PF13181.1 EPY51184.1 - 3.5e-23 79.5 14.9 0.081 12.7 0.1 14.5 15 1 1 16 16 15 6 Tetratricopeptide repeat TPR_9 PF13371.1 EPY51184.1 - 9.4e-18 63.8 3.8 0.0002 21.1 0.0 9.9 9 2 2 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPY51184.1 - 2.2e-13 48.9 11.5 0.52 10.2 0.0 11.8 14 0 0 14 14 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 EPY51184.1 - 3.2e-13 49.1 12.1 0.57 10.7 0.0 12.2 14 1 0 14 14 11 3 Tetratricopeptide repeat Apc3 PF12895.2 EPY51184.1 - 1.2e-12 47.7 32.8 0.0015 18.5 0.8 10.1 6 2 4 10 10 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EPY51184.1 - 1.3e-05 25.1 0.4 0.084 13.0 0.0 5.6 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EPY51184.1 - 0.00014 21.5 0.8 3.7 7.4 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPY51184.1 - 0.00024 21.2 0.5 22 5.8 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.17 EPY51184.1 - 0.00056 19.1 10.0 4.6 6.7 0.0 6.9 7 0 0 7 7 7 2 Protein prenyltransferase alpha subunit repeat PPR PF01535.15 EPY51184.1 - 0.033 14.1 2.1 11 6.2 0.0 4.8 4 0 0 4 4 4 0 PPR repeat TPR_10 PF13374.1 EPY51184.1 - 0.042 13.8 7.2 22 5.1 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Ribosomal_L36e PF01158.13 EPY51184.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L36e Colicin-DNase PF12639.2 EPY51184.1 - 0.19 11.9 1.3 0.35 11.1 0.2 2.0 2 0 0 2 2 1 0 DNase/tRNase domain of colicin-like bacteriocin Sec1 PF00995.18 EPY51185.1 - 3.1e-147 491.6 0.5 3.7e-147 491.3 0.4 1.0 1 0 0 1 1 1 1 Sec1 family Sif PF06767.6 EPY51186.1 - 0.036 12.8 0.0 0.083 11.6 0.0 1.6 2 0 0 2 2 2 0 Sif protein SBP_bac_3 PF00497.15 EPY51186.1 - 0.089 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Pkinase PF00069.20 EPY51187.1 - 6.8e-74 248.2 0.0 1.1e-73 247.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51187.1 - 3.6e-39 134.3 0.0 6.4e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EPY51187.1 - 2.2e-14 53.3 0.8 4.3e-14 52.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EPY51187.1 - 1.1e-09 37.6 0.0 5.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like YukC PF10140.4 EPY51187.1 - 0.00077 18.1 0.1 0.0011 17.5 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 EPY51187.1 - 0.075 12.0 0.3 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPY51187.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nic96 PF04097.9 EPY51188.1 - 1.6e-157 525.2 0.6 2.1e-157 524.9 0.4 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF2721 PF11026.3 EPY51189.1 - 0.033 13.8 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4234 PF14018.1 EPY51189.1 - 0.046 13.4 1.7 1.1 8.9 1.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) HSP70 PF00012.15 EPY51190.1 - 1e-271 902.1 4.9 1.2e-271 901.9 3.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPY51190.1 - 1e-16 60.4 0.2 1.1e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPY51190.1 - 0.00016 21.3 0.0 0.00045 19.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EPY51190.1 - 0.00092 18.3 1.0 0.019 14.0 0.1 2.7 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase Ppx-GppA PF02541.11 EPY51190.1 - 0.039 13.1 0.1 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Ppx/GppA phosphatase family TarH PF02203.10 EPY51190.1 - 0.49 10.2 3.4 0.94 9.2 2.4 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue His_Phos_1 PF00300.17 EPY51191.1 - 0.017 15.2 0.0 0.35 10.9 0.0 2.2 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) ADH_zinc_N PF00107.21 EPY51192.1 - 2.1e-24 85.5 0.0 3.3e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPY51192.1 - 7.2e-07 30.1 0.0 1.5e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ABC2_membrane PF01061.19 EPY51193.1 - 8.7e-69 230.8 63.5 7e-38 129.9 11.2 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPY51193.1 - 6.2e-22 78.3 0.0 5.4e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPY51193.1 - 2.8e-20 71.9 9.3 2.3e-12 46.4 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EPY51193.1 - 5.7e-05 22.3 23.9 5.7e-05 22.3 16.6 3.5 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EPY51193.1 - 0.073 12.4 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Metallophos PF00149.23 EPY51194.1 - 2e-43 148.1 0.0 2.4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 EPY51195.1 - 6.3e-33 111.8 53.0 3.3e-10 39.3 0.1 9.6 6 2 5 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPY51195.1 - 3.7e-24 84.2 50.0 3.9e-10 39.3 0.2 7.7 5 2 3 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EPY51195.1 - 2.5e-11 41.9 48.6 0.058 13.4 0.0 14.0 10 4 2 12 12 12 5 Leucine Rich Repeat LRR_7 PF13504.1 EPY51195.1 - 1.8e-07 30.2 45.0 0.35 11.2 0.0 14.6 15 0 0 15 15 15 4 Leucine rich repeat LRR_6 PF13516.1 EPY51195.1 - 1.6e-05 24.4 44.9 0.098 12.7 0.0 11.1 11 1 1 12 12 12 4 Leucine Rich repeat LRR_9 PF14580.1 EPY51195.1 - 0.072 12.6 13.9 3.9 6.9 2.2 4.4 2 2 2 4 4 4 0 Leucine-rich repeat SUR7 PF06687.7 EPY51196.1 - 9.7e-17 61.2 19.3 1.3e-16 60.7 13.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family GWT1 PF06423.7 EPY51196.1 - 3.2 7.8 9.6 0.57 10.2 3.5 2.1 1 1 1 2 2 2 0 GWT1 COX6A PF02046.10 EPY51197.1 - 1.2e-36 125.1 1.4 1.4e-36 124.9 1.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2207 PF09972.4 EPY51197.1 - 0.0047 15.5 0.1 0.0057 15.3 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF547 PF04784.9 EPY51197.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF547 adh_short_C2 PF13561.1 EPY51198.1 - 3.2e-29 102.4 0.1 4.1e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPY51198.1 - 6.5e-27 94.4 0.5 8e-27 94.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY51198.1 - 7.8e-17 61.5 0.3 1.1e-16 61.0 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1749 PF08538.5 EPY51198.1 - 0.00066 18.6 0.2 0.00094 18.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) THF_DHG_CYH_C PF02882.14 EPY51198.1 - 0.0011 18.1 1.9 0.0079 15.2 0.1 2.1 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EPY51198.1 - 0.0015 18.2 0.7 0.07 12.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPY51198.1 - 0.0042 16.5 2.1 0.0074 15.7 1.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACT PF01842.20 EPY51198.1 - 0.066 12.7 0.3 0.33 10.4 0.0 2.2 2 1 0 2 2 2 0 ACT domain Ribosomal_S13 PF00416.17 EPY51198.1 - 0.074 13.5 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Sas10_Utp3 PF04000.10 EPY51199.1 - 9.2e-16 57.8 2.4 9.2e-16 57.8 1.7 1.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Peptidase_C10 PF01640.12 EPY51199.1 - 0.022 14.5 0.7 0.024 14.4 0.5 1.1 1 0 0 1 1 1 0 Peptidase C10 family Rapamycin_bind PF08771.6 EPY51199.1 - 0.053 13.6 1.3 0.23 11.5 0.3 2.0 1 1 1 2 2 2 0 Rapamycin binding domain IF-2B PF01008.12 EPY51199.1 - 0.097 11.6 0.7 0.11 11.5 0.5 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF4363 PF14276.1 EPY51199.1 - 0.19 11.4 3.0 1.9 8.2 2.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) FlxA PF14282.1 EPY51199.1 - 0.33 10.9 4.5 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 FlxA-like protein FadA PF09403.5 EPY51199.1 - 2.2 8.3 7.6 7.2 6.6 1.5 2.6 1 1 0 2 2 2 0 Adhesion protein FadA Aldo_ket_red PF00248.16 EPY51200.1 - 6.4e-60 202.3 0.0 7.3e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TP_methylase PF00590.15 EPY51201.1 - 1.2e-47 162.3 0.0 1.8e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EPY51201.1 - 3.9e-11 43.1 0.0 9.5e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPY51201.1 - 0.0016 17.7 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Aldo_ket_red PF00248.16 EPY51202.1 - 2.6e-61 206.9 0.0 3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1113 PF06541.6 EPY51203.1 - 0.0047 16.7 0.8 0.0054 16.5 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1113) Cation_efflux PF01545.16 EPY51203.1 - 0.026 13.6 1.1 0.03 13.4 0.8 1.1 1 0 0 1 1 1 0 Cation efflux family DUF843 PF05814.6 EPY51203.1 - 0.5 10.1 6.5 0.87 9.4 4.5 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) PIG-P PF08510.7 EPY51203.1 - 0.57 9.8 5.1 1 8.9 3.6 1.5 1 1 0 1 1 1 0 PIG-P Ndc1_Nup PF09531.5 EPY51203.1 - 0.78 8.0 5.8 0.87 7.9 4.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PKD_channel PF08016.7 EPY51204.1 - 0.058 11.8 0.1 0.066 11.6 0.0 1.0 1 0 0 1 1 1 0 Polycystin cation channel SET PF00856.23 EPY51207.1 - 1.2e-11 45.1 0.0 1.8e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 SET domain ADH_zinc_N PF00107.21 EPY51208.1 - 2.4e-27 95.0 0.0 3.6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPY51208.1 - 2.3e-22 78.8 0.4 4.5e-22 77.8 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain VHP PF02209.14 EPY51209.1 - 0.058 13.0 0.1 0.058 13.0 0.1 1.8 2 0 0 2 2 2 0 Villin headpiece domain BK_channel_a PF03493.13 EPY51209.1 - 0.091 12.7 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit AAA_12 PF13087.1 EPY51210.1 - 4.8e-38 130.5 0.0 9.9e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPY51210.1 - 8.4e-29 100.8 0.6 2.5e-28 99.2 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPY51210.1 - 1.8e-10 40.7 0.0 8.6e-06 25.4 0.0 3.6 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 EPY51210.1 - 6.4e-10 38.6 0.1 1.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 EPY51210.1 - 1.6e-05 24.3 0.9 7.8e-05 22.1 0.6 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EPY51210.1 - 0.00012 21.6 0.0 0.039 13.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EPY51210.1 - 0.00021 20.4 0.3 0.0041 16.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EPY51210.1 - 0.00047 20.1 0.1 0.0036 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.11 EPY51210.1 - 0.00065 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.10 EPY51210.1 - 0.00065 19.5 0.1 0.0019 18.0 0.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPY51210.1 - 0.0036 16.8 0.1 0.0076 15.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.24 EPY51210.1 - 0.01 16.0 0.3 0.072 13.2 0.2 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY51210.1 - 0.031 14.4 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPY51210.1 - 0.042 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPY51210.1 - 0.058 13.1 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EPY51210.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ribosomal_L22 PF00237.14 EPY51211.1 - 3.8e-19 68.5 0.7 5e-19 68.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Arfaptin PF06456.8 EPY51211.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Arfaptin-like domain zf-CCCH PF00642.19 EPY51212.1 - 2.4e-09 36.6 11.2 0.00014 21.4 2.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPY51212.1 - 0.026 14.5 15.9 0.086 12.8 3.8 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type CUE PF02845.11 EPY51213.1 - 1.2e-05 24.7 0.2 3e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 CUE domain NTP_transferase PF00483.18 EPY51214.1 - 9.9e-52 175.7 0.0 2.4e-51 174.4 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EPY51214.1 - 3.3e-12 45.3 7.7 1e-10 40.5 0.7 3.9 3 1 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPY51214.1 - 1.2e-11 44.9 0.0 1.7e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EPY51214.1 - 3.7e-06 26.4 1.3 3.7e-06 26.4 0.9 3.3 4 1 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EPY51214.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Gly_transf_sug PF04488.10 EPY51215.1 - 2.5e-23 82.4 0.1 6.2e-23 81.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPY51215.1 - 0.004 15.7 6.6 0.37 9.2 0.2 2.3 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain PP2C PF00481.16 EPY51217.1 - 1.5e-74 250.6 0.1 2e-74 250.2 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPY51217.1 - 4.1e-05 23.0 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPY51217.1 - 0.017 14.8 0.1 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) GATA PF00320.22 EPY51218.1 - 1.4e-11 43.5 5.6 2.3e-11 42.8 3.9 1.4 1 0 0 1 1 1 1 GATA zinc finger Terminase_GpA PF05876.7 EPY51218.1 - 0.017 13.5 0.1 0.025 12.9 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF3414 PF11894.3 EPY51219.1 - 1.7e-181 605.4 42.4 2.2e-181 605.0 29.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) RNA_pol_Rpc34 PF05158.7 EPY51220.1 - 4.8e-96 321.7 0.0 9.8e-96 320.7 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit z-alpha PF02295.12 EPY51220.1 - 0.00037 20.2 0.1 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Adenosine deaminase z-alpha domain TrmB PF01978.14 EPY51220.1 - 0.0019 17.8 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.6 EPY51220.1 - 0.0034 17.7 0.0 0.017 15.4 0.0 2.2 2 1 0 2 2 2 1 Replication protein A C terminal HTH_24 PF13412.1 EPY51220.1 - 0.071 12.5 2.0 9.8 5.6 0.0 3.5 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding HTH_45 PF14947.1 EPY51220.1 - 0.099 12.4 0.5 0.27 11.0 0.0 2.0 3 0 0 3 3 3 0 Winged helix-turn-helix EndIII_4Fe-2S PF10576.4 EPY51220.1 - 0.13 12.4 3.0 0.24 11.6 2.1 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Lyase_1 PF00206.15 EPY51221.1 - 1.5e-110 369.2 0.0 1.9e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EPY51221.1 - 3.2e-23 81.5 0.0 6e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus Proteasom_PSMB PF10508.4 EPY51222.1 - 2.1e-09 36.1 0.0 3.6e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT PF02985.17 EPY51222.1 - 0.12 12.5 0.1 63 4.0 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Flavokinase PF01687.12 EPY51223.1 - 9e-39 132.2 0.0 1e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase WD40 PF00400.27 EPY51224.1 - 4.2e-06 26.4 7.6 0.67 9.9 0.2 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Ribosomal_L10 PF00466.15 EPY51225.1 - 2.4e-28 97.9 0.7 5e-28 96.9 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EPY51225.1 - 2.7e-15 56.5 6.2 3.9e-15 56.0 3.0 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein TA0956 PF11513.3 EPY51225.1 - 0.041 13.9 0.1 9.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 WD40 PF00400.27 EPY51226.1 - 5.4e-12 45.1 0.5 0.00046 19.9 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Fcf1 PF04900.7 EPY51227.1 - 1.7e-29 101.8 0.4 2.9e-29 101.1 0.3 1.4 1 0 0 1 1 1 1 Fcf1 Phos_pyr_kin PF08543.7 EPY51228.1 - 9.7e-15 54.4 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EPY51228.1 - 0.00011 21.5 0.0 0.00027 20.1 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HIT PF01230.18 EPY51229.1 - 8.4e-21 74.3 0.4 1.5e-20 73.5 0.3 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPY51229.1 - 3.1e-20 72.5 4.0 7.4e-20 71.3 2.7 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding tRNA-synt_2 PF00152.15 EPY51230.1 - 1.4e-81 273.8 0.1 1.8e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPY51230.1 - 1.4e-10 40.9 0.0 2.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPY51230.1 - 6.8e-09 35.2 0.2 0.00014 21.1 0.0 3.0 2 1 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPY51230.1 - 0.054 13.0 0.4 1 8.8 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) Mre11_DNA_bind PF04152.9 EPY51230.1 - 0.12 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain RNA_pol_Rpc4 PF05132.9 EPY51231.1 - 6.5e-30 103.7 0.1 6.5e-30 103.7 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase III RPC4 CAF1 PF04857.15 EPY51232.1 - 1.1e-66 224.8 0.0 1.6e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RNase_H_2 PF13482.1 EPY51232.1 - 0.019 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily WD40 PF00400.27 EPY51233.1 - 2e-87 284.2 32.9 8.8e-14 50.7 0.5 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EPY51233.1 - 1.2e-12 47.6 0.1 2.8e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 EPY51233.1 - 1e-08 35.1 0.1 0.0011 18.6 0.0 4.0 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPY51233.1 - 2.6e-07 29.1 10.5 0.029 12.4 0.0 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Gmad1 PF10647.4 EPY51233.1 - 0.00015 21.2 1.0 0.00032 20.1 0.1 1.8 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EPY51233.1 - 0.034 13.8 0.6 16 5.2 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EPY51233.1 - 0.043 12.1 0.2 0.14 10.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3312 PF11768.3 EPY51233.1 - 0.047 11.9 0.1 1.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Sec10 PF07393.6 EPY51234.1 - 2.2e-70 237.7 1.9 1.2e-69 235.3 1.3 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EPY51234.1 - 4.1e-06 26.4 0.4 1.9e-05 24.2 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPY51234.1 - 3.6e-05 23.3 1.7 8.2e-05 22.1 0.7 2.0 2 0 0 2 2 2 1 F-box domain R3H PF01424.17 EPY51235.1 - 2.9e-14 52.4 0.0 6.4e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EPY51235.1 - 0.00043 20.1 12.1 0.00043 20.1 8.4 13.3 14 1 0 14 14 14 8 NF-X1 type zinc finger CAF-1_p150 PF11600.3 EPY51235.1 - 0.0032 16.8 29.4 0.0032 16.8 20.4 1.8 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TORC_C PF12886.2 EPY51235.1 - 0.016 15.4 1.0 0.19 11.9 0.0 3.0 3 1 1 4 4 4 0 Transducer of regulated CREB activity, C terminus DUF4613 PF15390.1 EPY51235.1 - 1.1 7.3 14.6 0.33 9.0 8.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) MFS_1 PF07690.11 EPY51236.1 - 2e-48 164.9 33.6 1.6e-42 145.5 21.1 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPY51236.1 - 1.3 6.9 10.9 0.98 7.3 0.0 2.9 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family SUN PF03856.8 EPY51237.1 - 2.6e-74 249.6 15.5 4.3e-74 248.9 10.7 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ribosomal_S2 PF00318.15 EPY51238.1 - 3.6e-43 147.2 0.2 1.5e-20 73.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Response_reg PF00072.19 EPY51239.1 - 3.3e-17 62.5 0.0 1e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPY51239.1 - 8.4e-17 60.9 0.1 3e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 EPY51239.1 - 7e-08 31.9 0.3 3.9e-07 29.4 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 EPY51239.1 - 1.6e-07 31.5 0.0 3.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 EPY51239.1 - 2.1e-07 31.5 0.0 5.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EPY51239.1 - 1.9e-06 27.9 0.0 5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain PAS_3 PF08447.6 EPY51239.1 - 2.2e-06 27.6 0.0 7.4e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold Pkinase_Tyr PF07714.12 EPY51239.1 - 4.6e-05 22.6 0.0 0.00012 21.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase NB-ARC PF00931.17 EPY51239.1 - 6.8e-05 21.8 0.1 0.025 13.4 0.0 3.6 4 0 0 4 4 4 1 NB-ARC domain HATPase_c PF02518.21 EPY51239.1 - 0.00054 19.6 0.0 0.0017 18.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EPY51239.1 - 0.017 15.2 0.1 0.17 11.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain PAS_9 PF13426.1 EPY51239.1 - 0.025 14.9 0.0 0.068 13.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain NTPase_1 PF03266.10 EPY51239.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA PF00004.24 EPY51239.1 - 0.075 13.2 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPY51239.1 - 0.082 13.7 0.0 0.6 10.9 0.0 2.6 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 EPY51239.1 - 0.38 10.4 9.7 1.2 8.8 3.0 3.6 3 0 0 3 3 3 0 TPR repeat Ribosomal_L27e PF01777.13 EPY51240.1 - 2.7e-37 126.7 2.3 3.6e-37 126.3 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EPY51240.1 - 0.00028 20.4 0.1 0.00063 19.3 0.1 1.7 1 0 0 1 1 1 1 KOW motif AA_permease_2 PF13520.1 EPY51241.1 - 4.2e-64 216.6 43.1 5.3e-64 216.3 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPY51241.1 - 1.3e-17 63.3 37.7 1.7e-17 62.9 26.1 1.2 1 0 0 1 1 1 1 Amino acid permease Ammonium_transp PF00909.16 EPY51242.1 - 2.3e-115 385.2 25.0 2.6e-115 385.0 17.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AA_permease PF00324.16 EPY51243.1 - 5.4e-104 348.1 31.6 6.5e-104 347.9 21.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY51243.1 - 8.7e-39 133.2 35.3 1.1e-38 132.9 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EPY51244.1 - 6.9e-20 71.0 22.8 1.6e-19 69.8 15.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ComC PF03047.9 EPY51244.1 - 0.15 11.4 0.5 0.33 10.4 0.4 1.6 1 0 0 1 1 1 0 COMC family TauD PF02668.11 EPY51245.1 - 5.1e-44 150.8 0.2 1.1e-43 149.8 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EPY51245.1 - 0.0011 19.3 0.0 2 9.0 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Asp_Glu_race PF01177.17 EPY51246.1 - 2.2e-28 99.6 0.8 2.6e-28 99.4 0.6 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase FLO_LFY PF01698.11 EPY51246.1 - 0.061 12.1 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein AhpC-TSA PF00578.16 EPY51247.1 - 1.6e-38 131.1 0.0 2.1e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPY51247.1 - 2.7e-18 65.9 0.0 3.4e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EPY51247.1 - 9.2e-10 38.0 0.0 2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin LSM PF01423.17 EPY51248.1 - 8.8e-06 25.1 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF3047 PF11249.3 EPY51248.1 - 0.093 12.1 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) Bax1-I PF01027.15 EPY51249.1 - 1.1e-44 152.4 32.9 1.4e-44 152.2 22.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 tRNA-synt_1b PF00579.20 EPY51250.1 - 3.4e-74 249.5 0.0 4.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EPY51250.1 - 7.3e-05 22.1 0.0 0.00073 18.9 0.0 2.3 2 0 0 2 2 2 1 S4 domain SAC3_GANP PF03399.11 EPY51251.1 - 4.2e-59 199.5 3.1 8.7e-59 198.5 2.1 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPY51251.1 - 3.7e-05 23.5 3.3 5.7e-05 22.9 0.0 2.7 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 SAC3 PF12209.3 EPY51251.1 - 0.0062 16.6 1.3 0.077 13.1 0.2 2.7 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain PAM2 PF07145.10 EPY51251.1 - 0.026 14.0 1.4 0.039 13.4 0.2 2.0 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Clat_adaptor_s PF01217.15 EPY51252.1 - 2.7e-12 46.6 0.1 3.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain P53_tetramer PF07710.6 EPY51252.1 - 0.036 13.1 0.1 0.068 12.2 0.1 1.4 1 0 0 1 1 1 0 P53 tetramerisation motif Ribosomal_S5 PF00333.15 EPY51253.1 - 4.5e-28 96.7 3.1 5.4e-28 96.5 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EPY51253.1 - 1.4e-21 75.5 0.1 2.6e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S10 PF00338.17 EPY51254.1 - 2.7e-31 107.2 2.8 3.3e-31 106.9 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e DUF4469 PF14734.1 EPY51254.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold DUF3153 PF11353.3 EPY51254.1 - 0.12 11.8 0.1 0.16 11.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) AAA PF00004.24 EPY51255.1 - 1.3e-44 151.5 0.0 3e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPY51255.1 - 2.7e-08 33.6 0.1 9.3e-08 31.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPY51255.1 - 1.6e-07 31.4 0.0 5.9e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EPY51255.1 - 3.1e-07 30.4 0.0 9e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPY51255.1 - 2.9e-06 27.4 0.1 0.0008 19.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EPY51255.1 - 3.5e-06 26.1 0.0 5.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EPY51255.1 - 2.9e-05 23.2 0.0 6.7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPY51255.1 - 0.00036 20.5 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPY51255.1 - 0.00052 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPY51255.1 - 0.00054 19.5 0.0 0.0024 17.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPY51255.1 - 0.00059 19.5 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EPY51255.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPY51255.1 - 0.00085 19.0 0.0 0.038 13.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EPY51255.1 - 0.00093 20.0 0.0 0.0027 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPY51255.1 - 0.0014 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EPY51255.1 - 0.0016 18.1 0.1 0.0052 16.4 0.1 1.9 1 1 0 1 1 1 1 NTPase Zeta_toxin PF06414.7 EPY51255.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 EPY51255.1 - 0.0026 16.5 0.0 0.0066 15.2 0.0 1.5 1 1 1 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EPY51255.1 - 0.0032 16.8 1.1 0.069 12.5 0.0 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPY51255.1 - 0.0047 16.1 0.1 0.013 14.6 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EPY51255.1 - 0.0051 15.7 0.0 0.013 14.4 0.0 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein UPF0079 PF02367.12 EPY51255.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 EPY51255.1 - 0.0096 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.12 EPY51255.1 - 0.011 15.1 0.0 0.036 13.4 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 EPY51255.1 - 0.013 15.1 0.0 0.041 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EPY51255.1 - 0.014 15.1 0.0 0.049 13.3 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EPY51255.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY51255.1 - 0.022 14.6 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 EPY51255.1 - 0.044 12.5 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase KaiC PF06745.8 EPY51255.1 - 0.066 12.3 0.2 0.87 8.6 0.0 2.5 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.17 EPY51255.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 EPY51255.1 - 0.078 12.4 0.1 1.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.1 EPY51255.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EPY51255.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.14 EPY51255.1 - 0.13 11.6 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EPY51255.1 - 0.14 12.4 0.1 0.54 10.5 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Ribosomal_L15e PF00827.12 EPY51256.1 - 8e-89 296.2 9.2 9.7e-89 295.9 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 CENP-X PF09415.5 EPY51257.1 - 7.6e-22 76.9 0.2 8.9e-22 76.6 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X BCNT PF07572.7 EPY51258.1 - 6.7e-17 61.1 4.9 6.7e-17 61.1 3.4 2.0 2 0 0 2 2 2 1 Bucentaur or craniofacial development TP_methylase PF00590.15 EPY51259.1 - 1.4e-19 70.6 0.1 2.2e-19 69.9 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.20 EPY51260.1 - 1.1e-67 227.9 0.0 1.5e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51260.1 - 8.2e-32 110.2 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EPY51260.1 - 4.9e-07 29.5 0.9 2.5e-06 27.3 0.0 2.5 2 1 0 2 2 2 1 PH domain APH PF01636.18 EPY51260.1 - 0.0002 21.1 0.0 0.00063 19.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPY51260.1 - 0.00031 19.8 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY51260.1 - 0.0023 16.9 0.0 0.0066 15.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EPY51260.1 - 0.0031 16.8 0.1 0.006 15.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family LSM PF01423.17 EPY51261.1 - 1.7e-15 56.3 0.3 2.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPY51261.1 - 0.0066 16.3 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1461 PF07314.6 EPY51261.1 - 0.1 12.3 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) SRP19 PF01922.12 EPY51263.1 - 3.5e-22 78.7 0.2 5.1e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein Prp18 PF02840.10 EPY51264.1 - 6.2e-45 152.5 0.0 6.2e-45 152.5 0.0 2.4 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EPY51264.1 - 3.1e-08 32.7 0.3 8.4e-08 31.3 0.2 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like SAP18 PF06487.7 EPY51265.1 - 2.7e-21 75.5 0.0 3.3e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) NIF3 PF01784.13 EPY51266.1 - 4e-68 229.6 0.0 4.7e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RRM_1 PF00076.17 EPY51267.1 - 1.7e-09 37.1 0.0 3.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51267.1 - 6.6e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51267.1 - 8.1e-06 25.6 0.1 1.3e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPY51267.1 - 0.038 13.8 0.1 0.1 12.4 0.1 1.8 1 1 0 1 1 1 0 RNA binding motif Lipase_GDSL_2 PF13472.1 EPY51268.1 - 4.1e-19 69.4 0.0 5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPY51268.1 - 3.7e-14 53.1 0.0 7.6e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Zip PF02535.17 EPY51269.1 - 6.4e-41 140.3 8.3 9.2e-41 139.8 5.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Lectin_leg-like PF03388.8 EPY51270.1 - 3.1e-71 239.1 0.0 3.8e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EPY51270.1 - 0.00025 20.5 0.1 0.00048 19.5 0.1 1.4 1 1 0 1 1 1 1 Legume lectin domain PHD PF00628.24 EPY51271.1 - 8.2e-11 41.4 5.1 8.2e-11 41.4 3.5 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EPY51271.1 - 4.1e-10 39.3 27.9 4.2e-08 32.8 9.7 3.2 2 1 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EPY51271.1 - 5.4e-09 36.0 5.1 5.4e-09 36.0 3.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPY51271.1 - 1.9e-05 24.2 7.3 1.9e-05 24.2 5.1 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY51271.1 - 8.4e-05 22.5 3.9 8.4e-05 22.5 2.7 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY51271.1 - 0.00016 21.2 6.9 0.00016 21.2 4.8 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EPY51271.1 - 0.0025 17.0 1.0 0.0069 15.6 0.7 1.8 1 0 0 1 1 1 1 PHD-finger zf-Apc11 PF12861.2 EPY51271.1 - 0.0047 16.7 0.5 0.0047 16.7 0.4 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.1 EPY51271.1 - 0.011 15.0 0.8 0.011 15.0 0.6 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EPY51271.1 - 0.028 14.1 1.9 0.028 14.1 1.3 3.0 3 1 1 4 4 3 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EPY51271.1 - 5 6.9 9.8 0.42 10.3 0.2 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EPY51271.1 - 8.7 6.1 22.3 0.069 12.8 6.0 3.0 2 2 0 2 2 2 0 zinc-RING finger domain Cofilin_ADF PF00241.15 EPY51272.1 - 7.4e-23 80.8 3.2 1.4e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein MRP-L46 PF11788.3 EPY51273.1 - 7.6e-21 74.8 0.1 1.3e-20 74.1 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EPY51273.1 - 0.015 14.9 0.1 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Sec66 PF09802.4 EPY51273.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 SCA7 PF08313.7 EPY51274.1 - 9.4e-32 108.4 3.2 9.4e-32 108.4 2.2 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.6 EPY51274.1 - 0.0047 16.2 0.0 0.0085 15.3 0.0 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF1292 PF06949.6 EPY51274.1 - 0.032 14.5 0.1 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) zf-C2HC_2 PF13913.1 EPY51274.1 - 0.032 13.8 0.2 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type CDC27 PF09507.5 EPY51274.1 - 0.61 9.2 29.5 2.7 7.1 0.6 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Fiji_64_capsid PF05880.6 EPY51274.1 - 0.66 8.2 6.3 1.1 7.4 4.4 1.3 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein SOBP PF15279.1 EPY51274.1 - 3.5 7.9 15.4 5.5 7.2 10.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PseudoU_synth_1 PF01416.15 EPY51275.1 - 2.6e-20 72.7 0.0 4.6e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEADboxA PF12343.3 EPY51275.1 - 0.01 16.0 1.9 0.02 15.1 1.3 1.4 1 0 0 1 1 1 0 Cold shock protein DEAD box A Pec_lyase_N PF04431.8 EPY51275.1 - 0.044 13.8 1.0 0.12 12.4 0.7 1.8 1 0 0 1 1 1 0 Pectate lyase, N terminus Ku_N PF03731.10 EPY51276.1 - 8.4e-55 185.6 0.1 1.6e-54 184.7 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EPY51276.1 - 1.1e-43 149.0 0.0 2.3e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EPY51276.1 - 1.9e-16 60.3 0.1 7.3e-16 58.4 0.0 2.1 1 1 1 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EPY51276.1 - 7.1e-11 41.3 0.3 1.6e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 EPY51276.1 - 1.3e-05 25.4 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain HeH PF12949.2 EPY51276.1 - 0.00058 19.3 0.9 0.0025 17.3 0.6 2.1 1 1 0 1 1 1 1 HeH/LEM domain DUF3907 PF13047.1 EPY51276.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) WD40 PF00400.27 EPY51277.1 - 3.8e-34 115.3 9.5 1.2e-07 31.3 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPY51277.1 - 1.9e-06 26.3 5.9 0.038 12.1 0.1 4.3 3 2 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY51277.1 - 0.0034 16.1 2.8 7.8 5.1 0.0 4.1 1 1 2 4 4 4 2 Nup133 N terminal like MFS_1 PF07690.11 EPY51278.1 - 8.2e-24 83.9 42.3 6.7e-22 77.6 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY51278.1 - 3.1e-09 35.9 3.9 3.1e-09 35.9 2.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter WD40 PF00400.27 EPY51280.1 - 1.5e-15 56.3 11.1 0.00025 20.8 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EPY51280.1 - 1e-05 25.3 0.4 0.019 14.7 0.0 3.8 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EPY51280.1 - 0.0051 16.5 0.0 0.025 14.3 0.0 2.3 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EPY51280.1 - 0.087 10.6 0.0 0.2 9.4 0.0 1.6 1 1 0 1 1 1 0 IKI3 family PPTA PF01239.17 EPY51281.1 - 3.3e-43 143.2 20.8 1.9e-08 33.3 0.1 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Imm15 PF15590.1 EPY51281.1 - 0.026 13.5 0.0 0.07 12.2 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 15 SapC PF07277.6 EPY51281.1 - 0.037 13.3 1.1 0.081 12.2 0.1 1.9 2 0 0 2 2 2 0 SapC Pribosyltran_N PF13793.1 EPY51282.1 - 3.5e-49 165.3 0.1 2.4e-47 159.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPY51282.1 - 1.4e-44 151.9 3.6 9.4e-38 129.7 1.6 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPY51282.1 - 6.2e-12 45.3 1.7 1e-11 44.6 0.6 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPY51282.1 - 0.0078 15.4 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase TgMIC1 PF11476.3 EPY51282.1 - 0.12 11.8 0.3 0.44 10.0 0.1 2.0 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF2296 PF10058.4 EPY51283.1 - 7.1e-21 73.6 0.5 1.3e-20 72.8 0.3 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF485 PF04341.7 EPY51283.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 YfhO PF09586.5 EPY51283.1 - 0.55 8.1 2.2 16 3.3 0.0 2.0 1 1 1 2 2 2 0 Bacterial membrane protein YfhO ATP-grasp_2 PF08442.5 EPY51284.1 - 2.3e-74 249.1 0.0 3.4e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EPY51284.1 - 3.5e-23 81.8 0.3 5.4e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EPY51284.1 - 4.2e-05 22.8 0.0 0.00012 21.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain TFIIF_alpha PF05793.7 EPY51285.1 - 3e-20 72.0 21.6 4.4e-11 41.8 0.9 2.4 3 0 0 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vac7 PF12751.2 EPY51285.1 - 0.0017 17.3 0.1 0.0028 16.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 Bud13 PF09736.4 EPY51286.1 - 1e-44 152.2 8.3 1e-44 152.2 5.8 2.7 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex Nic96 PF04097.9 EPY51287.1 - 7.9e-177 589.0 0.2 1e-176 588.7 0.1 1.1 1 0 0 1 1 1 1 Nup93/Nic96 RabGAP-TBC PF00566.13 EPY51288.1 - 5e-12 45.7 0.1 5e-12 45.7 0.1 2.5 2 1 1 3 3 3 1 Rab-GTPase-TBC domain DUF2968 PF11180.3 EPY51288.1 - 1 8.7 15.3 0.73 9.1 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) TSC22 PF01166.13 EPY51288.1 - 1.9 8.5 14.5 0.31 11.0 0.5 4.1 1 1 3 4 4 4 0 TSC-22/dip/bun family Atg14 PF10186.4 EPY51288.1 - 2.4 7.0 16.9 5 5.9 11.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 EPY51288.1 - 3.3 7.5 21.2 17 5.2 8.0 2.3 1 1 0 1 1 1 0 Tropomyosin like Prefoldin_2 PF01920.15 EPY51288.1 - 3.3 7.4 20.3 0.24 11.2 1.9 3.6 1 1 2 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 EPY51288.1 - 3.6 5.3 10.0 6.3 4.5 7.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC155 PF14662.1 EPY51288.1 - 5 6.6 26.6 0.28 10.7 13.9 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF948 PF06103.6 EPY51288.1 - 6.3 6.7 8.2 3.3 7.6 0.3 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EPY51288.1 - 8.9 6.1 14.5 1.2e+02 2.5 7.5 3.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus His_Phos_1 PF00300.17 EPY51289.1 - 3.8e-25 88.8 0.0 5.7e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TroA PF01297.12 EPY51289.1 - 0.029 13.6 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family SNF2_N PF00176.18 EPY51290.1 - 7.4e-79 264.6 0.2 7.4e-79 264.6 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EPY51290.1 - 1.4e-21 76.2 0.1 3.9e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EPY51290.1 - 2e-18 66.0 0.1 9.8e-17 60.5 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EPY51290.1 - 3.4e-08 33.5 0.3 3.4e-08 33.5 0.2 2.5 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 EPY51290.1 - 3.9e-08 32.5 1.7 9e-08 31.4 1.2 1.7 1 0 0 1 1 1 1 QLQ ResIII PF04851.10 EPY51290.1 - 1.4e-06 28.3 0.0 1.4e-06 28.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.8 EPY51290.1 - 8.4e-06 25.4 10.6 1e-05 25.2 5.9 2.2 2 0 0 2 2 2 1 HSA ABC_membrane PF00664.18 EPY51291.1 - 1.1e-35 123.4 8.0 1.7e-35 122.7 5.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EPY51291.1 - 2.3e-32 112.1 0.0 3.8e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EPY51291.1 - 3.8e-07 29.5 0.0 2.2e-06 27.0 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPY51291.1 - 2.4e-05 24.4 2.0 0.00092 19.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPY51291.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY51291.1 - 0.0046 17.0 0.1 0.035 14.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EPY51291.1 - 0.015 15.1 0.1 0.11 12.4 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EPY51291.1 - 0.016 14.3 0.1 0.044 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPY51291.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EPY51291.1 - 0.035 13.1 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 EPY51291.1 - 0.056 13.6 0.0 0.43 10.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1659 PF07872.6 EPY51291.1 - 0.11 12.1 0.6 0.24 11.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) AAA_25 PF13481.1 EPY51291.1 - 0.11 11.8 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EPY51291.1 - 0.11 11.3 0.0 0.29 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EPY51291.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPY51292.1 - 7.4e-125 411.2 0.0 2e-20 72.9 0.0 10.5 10 0 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EPY51292.1 - 4e-31 107.9 0.8 1.9e-05 24.8 0.0 8.1 7 0 0 7 7 7 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EPY51292.1 - 1.4e-30 105.5 0.0 3.6e-09 36.3 0.0 7.4 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPY51292.1 - 1.3e-20 74.4 0.1 0.0022 18.8 0.0 7.9 7 0 0 7 7 6 3 AAA domain AAA_22 PF13401.1 EPY51292.1 - 3.6e-20 72.4 4.6 0.019 15.0 0.0 8.2 7 0 0 7 7 6 4 AAA domain AAA_16 PF13191.1 EPY51292.1 - 1.1e-19 71.1 0.2 0.0019 18.2 0.0 7.6 6 0 0 6 6 6 4 AAA ATPase domain AAA_33 PF13671.1 EPY51292.1 - 7.4e-18 64.7 0.0 0.091 12.6 0.0 7.2 6 0 0 6 6 6 5 AAA domain AAA_14 PF13173.1 EPY51292.1 - 1.2e-17 64.0 0.1 0.00036 20.4 0.0 8.4 7 1 0 7 7 6 3 AAA domain Zeta_toxin PF06414.7 EPY51292.1 - 2e-14 53.1 0.0 0.086 11.9 0.0 6.9 6 0 0 6 6 6 2 Zeta toxin AAA_19 PF13245.1 EPY51292.1 - 6.9e-14 51.3 3.7 0.083 12.6 0.0 6.5 6 0 0 6 6 6 3 Part of AAA domain T2SE PF00437.15 EPY51292.1 - 1.3e-13 50.4 0.6 0.0073 15.2 0.1 6.1 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_18 PF13238.1 EPY51292.1 - 2.2e-12 47.3 28.2 0.012 15.9 0.0 9.1 8 1 2 10 10 6 4 AAA domain Sigma54_activat PF00158.21 EPY51292.1 - 3.1e-12 46.2 0.0 0.47 9.8 0.0 6.3 6 0 0 6 6 6 3 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EPY51292.1 - 3.2e-11 43.4 6.3 0.029 14.4 0.0 7.3 9 0 0 9 9 6 3 Sigma-54 interaction domain AAA_25 PF13481.1 EPY51292.1 - 4.3e-11 42.5 0.6 0.047 13.0 0.0 6.7 6 0 0 6 6 6 2 AAA domain RNA_helicase PF00910.17 EPY51292.1 - 1.1e-10 41.6 2.2 0.71 10.0 0.0 7.6 7 0 0 7 7 7 2 RNA helicase MobB PF03205.9 EPY51292.1 - 1.6e-10 40.8 0.1 0.74 9.5 0.0 6.4 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EPY51292.1 - 3.1e-10 39.7 0.6 0.21 11.2 0.0 6.4 7 0 0 7 7 6 2 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EPY51292.1 - 1.2e-09 38.3 4.4 0.089 12.7 0.0 7.1 6 0 0 6 6 6 1 AAA domain Miro PF08477.8 EPY51292.1 - 1.4e-09 38.4 0.3 3.2 8.2 0.0 7.0 6 0 0 6 6 6 1 Miro-like protein RuvB_N PF05496.7 EPY51292.1 - 2.8e-09 36.3 1.3 0.083 11.9 0.0 6.2 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 EPY51292.1 - 3.2e-09 36.5 0.7 0.27 10.6 0.1 5.6 5 0 0 5 5 5 2 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EPY51292.1 - 3.7e-09 35.9 0.0 0.93 9.0 0.1 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain NACHT PF05729.7 EPY51292.1 - 7.4e-09 35.4 3.3 1.7 8.2 0.1 5.7 6 0 0 6 6 5 3 NACHT domain IstB_IS21 PF01695.12 EPY51292.1 - 1.4e-08 34.3 0.1 0.48 9.8 0.0 5.7 6 0 0 6 6 5 2 IstB-like ATP binding protein PduV-EutP PF10662.4 EPY51292.1 - 4.4e-08 32.7 1.5 0.052 13.0 0.0 5.3 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EPY51292.1 - 5.1e-08 32.2 0.9 1.7 7.8 0.0 5.8 6 0 0 6 6 6 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPY51292.1 - 3e-07 30.8 28.6 0.0011 19.2 0.0 7.9 9 0 0 9 9 6 2 ABC transporter Mg_chelatase PF01078.16 EPY51292.1 - 6.4e-07 28.7 3.1 4.7 6.3 0.0 7.8 9 1 1 10 10 10 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 EPY51292.1 - 0.0007 19.0 0.0 1.8 7.9 0.0 4.7 5 0 0 5 5 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 EPY51292.1 - 0.0013 18.5 4.3 19 4.9 0.0 5.1 5 0 0 5 5 4 0 NTPase tRNA_lig_kinase PF08303.6 EPY51292.1 - 0.0018 18.1 1.1 0.21 11.4 0.0 3.4 3 0 0 3 3 2 1 tRNA ligase kinase domain FtsK_SpoIIIE PF01580.13 EPY51292.1 - 0.0022 17.5 1.5 1.9 7.8 0.1 4.7 5 0 0 5 5 4 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EPY51292.1 - 0.0033 17.3 2.8 13 5.8 0.0 5.6 6 0 0 6 6 6 0 50S ribosome-binding GTPase AAA_6 PF12774.2 EPY51292.1 - 0.039 13.4 0.0 3.2 7.2 0.0 3.6 4 0 0 4 4 3 0 Hydrolytic ATP binding site of dynein motor region D1 DBI_PRT PF02277.12 EPY51292.1 - 2.2 7.2 0.3 9.9 5.1 0.1 2.1 3 0 0 3 3 3 0 Phosphoribosyltransferase ProSAAS PF07259.7 EPY51292.1 - 6.4 6.2 1.3 12 5.3 0.9 1.3 1 0 0 1 1 1 0 ProSAAS precursor AAA_11 PF13086.1 EPY51293.1 - 4.2e-57 193.4 0.0 6.6e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EPY51293.1 - 5.2e-56 189.2 0.0 1.8e-55 187.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPY51293.1 - 1e-12 47.6 0.5 1.7e-11 43.6 0.1 2.7 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EPY51293.1 - 2.8e-11 43.3 0.1 3.2e-09 36.6 0.0 2.8 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 EPY51293.1 - 3.7e-06 26.6 0.2 0.36 10.2 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EPY51293.1 - 3e-05 23.4 0.0 9.2e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EPY51293.1 - 3.2e-05 23.0 0.1 0.00016 20.7 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPY51293.1 - 7.3e-05 22.9 0.0 0.0076 16.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain ResIII PF04851.10 EPY51293.1 - 0.00013 21.8 0.1 0.0016 18.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EPY51293.1 - 0.0004 19.6 0.0 0.67 9.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.1 EPY51293.1 - 0.00082 19.4 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 EPY51293.1 - 0.0029 17.2 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 1 Helicase Zot PF05707.7 EPY51293.1 - 0.0037 16.7 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 EPY51293.1 - 0.004 17.3 0.0 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 EPY51293.1 - 0.0061 15.2 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.9 EPY51293.1 - 0.0065 15.4 0.0 0.77 8.6 0.0 3.5 4 0 0 4 4 4 1 PIF1-like helicase IstB_IS21 PF01695.12 EPY51293.1 - 0.0095 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein CbiA PF01656.18 EPY51293.1 - 0.011 15.1 0.1 0.047 13.0 0.1 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD_C PF13361.1 EPY51293.1 - 0.012 15.0 0.4 0.78 9.1 0.0 3.2 3 1 1 4 4 4 0 UvrD-like helicase C-terminal domain 4HB_MCP_1 PF12729.2 EPY51293.1 - 0.013 14.8 0.9 0.11 11.9 0.0 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction MobB PF03205.9 EPY51293.1 - 0.014 15.1 0.1 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EPY51293.1 - 0.02 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EPY51293.1 - 0.048 13.0 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPY51293.1 - 0.049 13.3 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 EPY51293.1 - 0.054 12.9 0.0 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 EPY51293.1 - 0.062 12.9 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EPY51293.1 - 0.093 12.6 0.3 5.4 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EPY51293.1 - 0.11 13.3 0.4 0.59 10.9 0.3 2.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY51293.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.16 EPY51294.1 - 2.9e-06 26.2 0.0 3.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Mononeg_RNA_pol PF00946.14 EPY51294.1 - 0.0044 14.4 0.0 0.0052 14.2 0.0 1.1 1 0 0 1 1 1 1 Mononegavirales RNA dependent RNA polymerase Pex24p PF06398.6 EPY51295.1 - 7.3e-12 44.7 18.9 5e-08 32.1 8.3 3.0 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin DUF2238 PF09997.4 EPY51295.1 - 0.092 12.1 2.1 0.16 11.3 1.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) DUF3529 PF12046.3 EPY51295.1 - 5.3 6.0 5.7 1.7 7.6 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3529) Cys_Met_Meta_PP PF01053.15 EPY51296.1 - 4.8e-123 410.2 0.0 5.4e-123 410.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPY51296.1 - 7.6e-08 31.6 0.0 1.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EPY51296.1 - 6.2e-05 21.4 0.0 0.00011 20.6 0.0 1.4 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 EPY51296.1 - 0.0036 16.0 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 EPY51296.1 - 0.005 15.5 0.0 0.0079 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.12 EPY51296.1 - 0.022 13.7 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_C13 PF01650.13 EPY51297.1 - 1e-40 139.6 0.2 1.3e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Dynamitin PF04912.9 EPY51298.1 - 2.7e-10 39.6 13.8 2.9e-08 32.9 2.5 2.7 3 1 0 3 3 3 2 Dynamitin Occludin_ELL PF07303.8 EPY51298.1 - 0.064 14.0 3.6 0.4 11.4 0.1 3.1 3 0 0 3 3 3 0 Occludin homology domain DUF1539 PF07560.6 EPY51298.1 - 0.81 9.5 8.6 0.37 10.6 1.8 3.1 3 2 0 3 3 3 0 Domain of Unknown Function (DUF1539) Tropomyosin PF00261.15 EPY51298.1 - 1.2 8.1 6.6 1.6 7.7 0.2 3.1 3 0 0 3 3 3 0 Tropomyosin COG2 PF06148.6 EPY51298.1 - 2.5 7.9 8.5 3.8 7.3 0.9 3.6 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 ATP13 PF12921.2 EPY51299.1 - 4.8e-26 90.5 0.0 4.1e-25 87.5 0.0 2.4 2 1 1 3 3 3 1 Mitochondrial ATPase expression PPR PF01535.15 EPY51299.1 - 0.024 14.6 0.0 0.47 10.5 0.0 2.6 2 0 0 2 2 2 0 PPR repeat PPR_1 PF12854.2 EPY51299.1 - 0.038 13.4 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 PPR repeat XPG_I PF00867.13 EPY51300.1 - 5.7e-23 80.7 0.0 1.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPY51300.1 - 4.6e-06 26.8 0.0 8.5e-05 22.7 0.0 2.9 3 0 0 3 3 3 1 XPG N-terminal domain GDA1_CD39 PF01150.12 EPY51301.1 - 6.6e-108 360.9 0.0 8.4e-108 360.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PAXNEB PF05625.6 EPY51302.1 - 3.8e-93 312.2 0.0 4.2e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein IF-2B PF01008.12 EPY51303.1 - 1.7e-65 220.8 0.0 2.1e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family CPSF_A PF03178.10 EPY51304.1 - 5.2e-21 75.0 0.3 1.4e-19 70.4 0.1 2.6 2 0 0 2 2 2 2 CPSF A subunit region Alpha-amylase PF00128.19 EPY51305.1 - 2.4e-69 234.1 1.1 3.1e-69 233.7 0.8 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF187 PF02638.10 EPY51305.1 - 4.8e-05 22.3 0.2 8.1e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 Glyco_hydro_31 PF01055.21 EPY51305.1 - 5.3e-05 22.2 3.5 5.3e-05 22.2 2.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 hDGE_amylase PF14701.1 EPY51305.1 - 0.00024 20.1 0.0 0.0005 19.0 0.0 1.5 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme DUF1966 PF09260.6 EPY51305.1 - 0.0043 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_66 PF13199.1 EPY51305.1 - 0.071 11.5 1.3 0.12 10.7 0.9 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Aminotran_5 PF00266.14 EPY51305.1 - 0.14 10.9 0.1 0.26 9.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V B56 PF01603.15 EPY51306.1 - 7.3e-159 528.7 4.8 9.5e-159 528.3 3.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 EPY51306.1 - 0.00035 20.0 7.9 0.012 15.0 0.3 3.4 2 1 1 3 3 3 3 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2122 PF09895.4 EPY51306.1 - 0.0041 17.2 0.7 0.017 15.3 0.0 2.3 2 0 0 2 2 2 1 RecB-family nuclease (DUF2122) Cnd3 PF12719.2 EPY51307.1 - 2e-76 256.8 2.6 2e-76 256.8 1.8 2.1 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EPY51307.1 - 1.7e-08 34.6 2.6 2.9e-05 24.2 0.1 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EPY51307.1 - 0.0044 16.9 8.7 1.1 9.5 0.0 6.4 7 1 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EPY51307.1 - 0.14 12.6 5.7 1 9.9 0.0 4.2 4 1 1 5 5 5 0 HEAT-like repeat SRP54 PF00448.17 EPY51308.1 - 3.1e-80 268.2 0.8 9.6e-79 263.3 0.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EPY51308.1 - 4.5e-23 81.4 5.0 4.5e-23 81.4 3.4 3.8 2 1 2 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 EPY51308.1 - 1.7e-15 56.8 0.7 3.4e-15 55.8 0.5 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EPY51308.1 - 4.6e-08 33.0 0.1 1.1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPY51308.1 - 4.8e-07 29.3 0.5 2.2e-06 27.2 0.4 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EPY51308.1 - 6.9e-07 28.5 0.1 3.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin ArgK PF03308.11 EPY51308.1 - 2.1e-05 23.4 0.4 0.00032 19.5 0.2 2.3 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 EPY51308.1 - 6.3e-05 22.7 0.0 0.00019 21.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EPY51308.1 - 6.9e-05 22.3 0.1 0.00038 19.9 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EPY51308.1 - 0.00056 20.7 0.0 0.001 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPY51308.1 - 0.0006 19.3 0.2 0.0011 18.4 0.1 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EPY51308.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY51308.1 - 0.0032 17.6 0.1 0.015 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPY51308.1 - 0.0041 16.7 0.1 0.0076 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPY51308.1 - 0.0057 16.3 0.0 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain 6PF2K PF01591.13 EPY51308.1 - 0.0069 15.4 0.2 0.032 13.2 0.0 2.1 3 0 0 3 3 3 1 6-phosphofructo-2-kinase APS_kinase PF01583.15 EPY51308.1 - 0.0071 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Torsin PF06309.6 EPY51308.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.1 EPY51308.1 - 0.017 15.3 0.1 0.06 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EPY51308.1 - 0.017 14.3 0.5 0.77 8.9 0.1 3.0 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EPY51308.1 - 0.018 14.6 0.3 0.055 13.0 0.0 1.9 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 EPY51308.1 - 0.033 13.5 0.1 0.078 12.3 0.1 1.6 1 0 0 1 1 1 0 Thymidylate kinase TrwB_AAD_bind PF10412.4 EPY51308.1 - 0.059 11.9 0.1 0.37 9.3 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 EPY51308.1 - 0.14 12.3 1.5 0.4 10.8 0.1 2.6 3 1 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EPY51308.1 - 0.29 10.9 1.6 3.3 7.4 0.1 2.4 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EPY51309.1 - 9.1e-29 100.2 1.2 1.9e-28 99.1 0.0 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 R3H PF01424.17 EPY51309.1 - 0.016 14.8 0.0 0.058 13.0 0.0 2.0 1 0 0 1 1 1 0 R3H domain DivIC PF04977.10 EPY51309.1 - 0.26 10.7 19.8 0.13 11.8 0.7 3.6 2 1 1 3 3 3 0 Septum formation initiator DUF848 PF05852.6 EPY51309.1 - 1.2 8.9 20.4 0.12 12.2 5.0 3.4 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Tropomyosin PF00261.15 EPY51309.1 - 1.6 7.7 28.9 0.4 9.7 1.9 2.7 1 1 1 2 2 2 0 Tropomyosin GAS PF13851.1 EPY51309.1 - 2.3 7.3 31.7 3.4 6.8 14.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 EPY51309.1 - 5.7 6.9 28.7 0.43 10.5 7.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EPY51309.1 - 5.9 4.6 12.7 10 3.8 8.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family USP7_ICP0_bdg PF12436.3 EPY51310.1 - 1.1e-63 214.8 0.3 6e-62 209.1 0.0 2.5 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EPY51310.1 - 2e-57 194.3 1.2 3e-57 193.7 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EPY51310.1 - 1.3e-51 175.0 8.0 6.8e-49 166.1 1.2 3.1 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EPY51310.1 - 4.2e-30 105.2 0.0 6.8e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1233 PF06806.7 EPY51311.1 - 0.088 12.3 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Putative excisionase (DUF1233) SKIP_SNW PF02731.10 EPY51312.1 - 1.3e-65 219.7 3.9 1.3e-65 219.7 2.7 2.0 2 0 0 2 2 2 1 SKIP/SNW domain Ribonuclease_3 PF00636.21 EPY51313.1 - 3.6e-43 146.6 0.0 2.9e-23 82.5 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPY51313.1 - 3.8e-26 91.5 0.2 3.7e-15 56.0 0.3 3.7 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EPY51313.1 - 1.5e-20 72.7 0.1 3.7e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EPY51313.1 - 4.2e-18 64.9 0.2 1.4e-17 63.3 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY51313.1 - 2e-12 47.3 0.6 7.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPY51313.1 - 2.6e-10 40.0 0.0 5.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Septin PF00735.13 EPY51314.1 - 3.2e-100 334.7 0.9 3.2e-100 334.7 0.6 1.3 2 0 0 2 2 1 1 Septin AAA_22 PF13401.1 EPY51314.1 - 0.0001 22.4 0.0 0.00079 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPY51314.1 - 0.00021 20.8 1.3 0.0048 16.4 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EPY51314.1 - 0.00052 19.9 0.0 0.0023 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPY51314.1 - 0.0011 19.2 3.8 0.0022 18.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EPY51314.1 - 0.0013 18.2 2.6 0.19 11.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.9 EPY51314.1 - 0.0019 17.2 0.2 0.0031 16.5 0.2 1.2 1 0 0 1 1 1 1 KAP family P-loop domain RNA_helicase PF00910.17 EPY51314.1 - 0.002 18.2 0.0 0.006 16.7 0.0 1.9 1 0 0 1 1 1 1 RNA helicase DUF258 PF03193.11 EPY51314.1 - 0.0025 17.0 0.1 0.0061 15.7 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPY51314.1 - 0.0025 17.7 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EPY51314.1 - 0.0025 18.1 0.1 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter T2SE PF00437.15 EPY51314.1 - 0.0061 15.4 0.4 0.019 13.9 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Pox_A32 PF04665.7 EPY51314.1 - 0.007 15.6 0.9 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_24 PF13479.1 EPY51314.1 - 0.0086 15.6 0.6 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPY51314.1 - 0.01 15.9 0.1 0.22 11.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPY51314.1 - 0.011 15.4 0.1 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EPY51314.1 - 0.014 15.9 0.1 0.077 13.5 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 EPY51314.1 - 0.02 13.8 0.1 0.64 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EPY51314.1 - 0.022 14.2 0.4 0.085 12.3 0.1 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 EPY51314.1 - 0.034 13.7 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EPY51314.1 - 0.044 13.7 0.1 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.21 EPY51314.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.17 EPY51314.1 - 0.096 12.1 0.1 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Fzo_mitofusin PF04799.8 EPY51314.1 - 0.11 11.9 1.0 0.3 10.4 0.7 1.8 1 0 0 1 1 1 0 fzo-like conserved region AAA_29 PF13555.1 EPY51314.1 - 0.15 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EPY51314.1 - 0.41 11.4 6.8 0.15 12.8 0.5 2.7 1 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EPY51314.1 - 0.96 9.2 6.2 1.6 8.5 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EPY51314.1 - 1.5 8.6 4.6 11 5.7 0.0 3.1 2 1 1 3 3 3 0 Dynamin family KaiC PF06745.8 EPY51314.1 - 2.1 7.3 5.5 1.1 8.2 0.1 2.5 3 0 0 3 3 3 0 KaiC IncA PF04156.9 EPY51314.1 - 2.2 7.8 4.9 4.5 6.8 3.4 1.5 1 0 0 1 1 1 0 IncA protein Svf1 PF08622.5 EPY51316.1 - 1.1e-114 382.8 0.0 1.4e-114 382.5 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EPY51316.1 - 2.9e-06 26.8 0.2 4.9e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Hydroxyneurosporene synthase (CrtC) AA_permease_2 PF13520.1 EPY51317.1 - 1.4e-64 218.2 42.2 1.4e-64 218.2 29.2 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EPY51317.1 - 1.6e-20 72.9 35.4 1.6e-20 72.9 24.5 1.3 1 1 0 1 1 1 1 Amino acid permease DUF3959 PF13105.1 EPY51317.1 - 0.096 12.0 0.8 0.21 10.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Atx10homo_assoc PF09759.4 EPY51318.1 - 7.1e-33 112.3 0.2 1.5e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arrestin_N PF00339.24 EPY51319.1 - 1.1e-25 90.2 0.0 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPY51319.1 - 3.5e-20 72.5 0.0 1.9e-17 63.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EPY51319.1 - 0.00072 19.1 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like CBM_25 PF03423.8 EPY51320.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) FAD_binding_1 PF00667.15 EPY51321.1 - 2.4e-69 233.1 0.0 4.5e-69 232.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPY51321.1 - 6.9e-09 36.2 0.0 2.2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPY51321.1 - 0.056 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ran-binding PF05508.6 EPY51322.1 - 7.8e-88 294.2 2.0 1.1e-87 293.8 1.4 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EPY51323.1 - 5.8e-47 159.5 0.0 9e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPY51323.1 - 2.4e-26 91.7 0.6 5.6e-26 90.6 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPY51323.1 - 1e-07 31.9 0.3 2.4e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPY51323.1 - 0.00014 21.8 0.0 0.00035 20.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsH_ext PF06480.10 EPY51323.1 - 1.3 9.2 4.0 3.7 7.7 1.1 2.9 3 1 0 3 3 3 0 FtsH Extracellular Sec1 PF00995.18 EPY51324.1 - 1e-123 413.9 1.1 1.2e-123 413.6 0.8 1.1 1 0 0 1 1 1 1 Sec1 family RPA_C PF08784.6 EPY51325.1 - 7.3e-18 64.8 0.1 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EPY51325.1 - 1.4e-07 31.2 0.1 2.2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Git3 PF11710.3 EPY51326.1 - 2.6e-44 151.2 14.4 2.6e-44 151.2 10.0 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPY51326.1 - 2.5e-07 30.3 0.4 2.5e-07 30.3 0.3 2.5 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_2 PF00002.19 EPY51326.1 - 0.0035 16.4 8.1 0.0035 16.4 5.6 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Syndecan PF01034.15 EPY51326.1 - 0.47 10.1 4.7 0.72 9.5 0.4 2.7 2 0 0 2 2 2 0 Syndecan domain DUF1774 PF08611.5 EPY51326.1 - 6.2 7.0 10.9 6.4 7.0 0.1 4.0 4 0 0 4 4 4 0 Fungal protein of unknown function (DUF1774) Meiotic_rec114 PF03525.9 EPY51327.1 - 8.3e-33 113.2 0.4 1.5e-32 112.4 0.3 1.4 1 1 0 1 1 1 1 Meiotic recombination protein rec114 Meiotic_rec114 PF03525.9 EPY51328.1 - 8.8e-64 215.0 0.3 1.5e-63 214.3 0.2 1.4 1 1 0 1 1 1 1 Meiotic recombination protein rec114 Inositol_P PF00459.20 EPY51329.1 - 1.2e-53 182.1 0.1 6e-53 179.8 0.0 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.8 EPY51330.1 - 3.3e-25 88.4 10.3 1e-21 77.0 2.2 3.1 1 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EPY51330.1 - 5.5e-17 61.3 6.0 4.7e-16 58.4 0.5 2.7 2 0 0 2 2 2 2 Rsm1-like BIR PF00653.16 EPY51330.1 - 0.00046 20.5 3.1 0.44 11.0 0.4 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain TCO89 PF10452.4 EPY51331.1 - 1.4e-25 90.2 4.6 5.9e-16 58.4 1.1 2.1 2 0 0 2 2 2 2 TORC1 subunit TCO89 PRK PF00485.13 EPY51332.1 - 2.9e-62 209.7 0.0 4e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EPY51332.1 - 4e-27 94.7 0.2 6e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EPY51332.1 - 1.9e-11 44.8 0.0 4.8e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY51332.1 - 1.6e-07 31.6 0.0 5.9e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY51332.1 - 7e-05 22.7 0.0 0.00078 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPY51332.1 - 0.00013 21.0 0.0 0.0003 19.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 EPY51332.1 - 0.0068 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPY51332.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EPY51332.1 - 0.02 15.1 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter SKI PF01202.17 EPY51332.1 - 0.024 14.5 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_5 PF07728.9 EPY51332.1 - 0.029 14.0 0.0 0.091 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EPY51332.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EPY51332.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EPY51332.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 EPY51332.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EPY51332.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Pkinase PF00069.20 EPY51333.1 - 7.6e-56 189.1 0.1 9.5e-56 188.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51333.1 - 5.5e-32 110.8 0.0 7.1e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51333.1 - 1.9e-07 30.3 0.0 9.9e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 EPY51333.1 - 0.00057 18.8 0.2 0.0011 17.9 0.1 1.5 1 1 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EPY51333.1 - 0.0009 18.3 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPY51333.1 - 0.0021 17.8 0.0 0.0053 16.5 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family HMG-CoA_red PF00368.13 EPY51334.1 - 5.1e-155 515.7 2.0 6.6e-155 515.3 1.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EPY51334.1 - 0.0059 16.3 0.4 0.013 15.2 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif TPR_MLP1_2 PF07926.7 EPY51335.1 - 8.5e-22 77.3 14.6 8.5e-22 77.3 10.1 15.6 5 4 8 15 15 15 5 TPR/MLP1/MLP2-like protein Filament PF00038.16 EPY51335.1 - 0.00013 21.5 29.3 0.00013 21.5 20.3 10.3 2 2 7 9 9 9 2 Intermediate filament protein DivIC PF04977.10 EPY51335.1 - 0.0058 16.0 2.9 0.0058 16.0 2.0 21.1 15 7 8 23 23 23 9 Septum formation initiator ADIP PF11559.3 EPY51335.1 - 0.0094 15.8 1.3 0.0094 15.8 0.9 20.8 6 5 13 21 21 21 8 Afadin- and alpha -actinin-Binding ENTH PF01417.15 EPY51336.1 - 1.5e-35 121.8 0.1 2.2e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 EPY51336.1 - 4e-24 84.4 139.3 6e-08 32.6 23.3 7.2 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) DUF2992 PF11208.3 EPY51336.1 - 6.6 6.6 9.2 14 5.5 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Methyltransf_23 PF13489.1 EPY51337.1 - 1.4e-26 93.1 0.0 2.2e-26 92.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY51337.1 - 4e-22 78.4 0.0 5.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY51337.1 - 9.4e-21 74.1 0.0 1.6e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY51337.1 - 4.3e-18 65.9 0.0 8.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY51337.1 - 2.8e-16 59.7 0.0 6.8e-16 58.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EPY51337.1 - 1.7e-12 47.0 0.0 2.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EPY51337.1 - 2.1e-11 43.5 0.0 2.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EPY51337.1 - 3.7e-10 40.0 0.0 6.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY51337.1 - 3.9e-09 36.1 0.0 6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EPY51337.1 - 4.8e-08 32.6 0.0 6.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 EPY51337.1 - 9.1e-08 31.1 0.0 1.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 EPY51337.1 - 3.9e-07 30.1 0.0 1.1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPY51337.1 - 9.1e-07 28.0 0.0 1.5e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 EPY51337.1 - 1e-06 28.0 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EPY51337.1 - 5.3e-05 22.9 0.0 9.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPY51337.1 - 0.00022 20.4 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.15 EPY51337.1 - 0.00036 19.6 0.0 0.00062 18.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TPMT PF05724.6 EPY51337.1 - 0.00042 19.8 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 EPY51337.1 - 0.01 15.2 0.1 0.023 14.1 0.1 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.5 EPY51337.1 - 0.034 13.7 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GidB PF02527.10 EPY51337.1 - 0.046 12.8 0.1 0.15 11.2 0.1 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.14 EPY51337.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.13 EPY51337.1 - 0.11 11.7 0.3 0.73 9.0 0.1 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Snf7 PF03357.16 EPY51338.1 - 3.1e-48 163.3 22.4 4e-48 163.0 15.6 1.0 1 0 0 1 1 1 1 Snf7 Cwf_Cwc_15 PF04889.7 EPY51338.1 - 0.0029 17.3 9.6 0.0037 17.0 6.6 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Prefoldin_2 PF01920.15 EPY51338.1 - 0.0036 17.0 18.0 0.13 12.0 0.0 3.6 2 1 1 3 3 3 1 Prefoldin subunit GAS PF13851.1 EPY51338.1 - 0.0051 16.0 13.4 0.048 12.8 8.7 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Filament PF00038.16 EPY51338.1 - 0.011 15.2 15.8 0.41 10.0 0.2 2.1 1 1 1 2 2 2 0 Intermediate filament protein Spatacsin_C PF14649.1 EPY51338.1 - 0.029 13.2 6.0 0.034 13.0 4.2 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus TFR_dimer PF04253.10 EPY51338.1 - 0.037 13.6 4.1 0.31 10.5 0.0 3.0 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain DUF3584 PF12128.3 EPY51338.1 - 0.18 9.1 17.1 0.22 8.8 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EPY51338.1 - 0.36 10.5 22.7 1 9.1 12.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EPY51338.1 - 0.58 10.1 20.0 0.28 11.1 5.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FUSC PF04632.7 EPY51338.1 - 0.62 8.4 4.4 0.75 8.1 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin PF02996.12 EPY51338.1 - 0.84 9.2 0.0 0.84 9.2 0.0 4.0 2 1 2 4 4 4 0 Prefoldin subunit DUF4140 PF13600.1 EPY51338.1 - 0.86 10.0 12.6 2.7 8.4 0.0 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 EPY51338.1 - 0.92 9.1 16.8 7.4 6.1 10.2 2.3 1 1 1 2 2 2 0 Mnd1 family AAA_13 PF13166.1 EPY51338.1 - 0.99 7.7 13.3 2.5 6.4 9.2 1.7 1 1 0 1 1 1 0 AAA domain NuA4 PF09340.5 EPY51338.1 - 1.1 8.9 6.5 0.16 11.6 1.0 2.2 3 0 0 3 3 2 0 Histone acetyltransferase subunit NuA4 APG6 PF04111.7 EPY51338.1 - 1.2 8.1 18.2 1.2 8.1 6.7 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 TBPIP PF07106.8 EPY51338.1 - 1.7 8.1 21.1 3.2 7.2 7.2 3.2 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF155 PF02582.9 EPY51338.1 - 2.6 7.9 7.9 4.2 7.2 5.3 1.3 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 DUF484 PF04340.7 EPY51338.1 - 2.6 7.4 12.2 0.94 8.9 5.2 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF484 ADIP PF11559.3 EPY51338.1 - 3 7.7 18.9 2.6 7.9 2.4 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF883 PF05957.8 EPY51338.1 - 3.1 8.2 7.3 0.82 10.1 0.4 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF342 PF03961.8 EPY51338.1 - 3.2 6.0 12.4 0.24 9.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Allexi_40kDa PF05549.6 EPY51338.1 - 4.2 6.5 9.6 11 5.1 0.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein OmpH PF03938.9 EPY51338.1 - 6 6.7 26.6 45 3.9 12.3 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 EPY51338.1 - 9.6 6.4 13.8 41 4.4 9.6 1.8 1 1 0 1 1 1 0 AAA domain SAPS PF04499.10 EPY51339.1 - 1.1e-162 542.0 0.0 1.1e-162 542.0 0.0 2.9 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Dus PF01207.12 EPY51340.1 - 5.7e-65 219.1 0.0 7.1e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EPY51340.1 - 0.00095 18.2 0.0 0.0023 16.9 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Resolvase PF00239.16 EPY51340.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Resolvase, N terminal domain PEP_mutase PF13714.1 EPY51340.1 - 0.084 12.0 0.1 0.34 10.0 0.1 1.7 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase Pkinase PF00069.20 EPY51341.1 - 2.1e-53 181.1 0.2 3.5e-53 180.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51341.1 - 1e-22 80.4 0.3 6.6e-22 77.8 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EPY51341.1 - 0.0045 16.3 1.1 0.045 13.0 0.7 2.2 1 1 0 1 1 1 1 RIO1 family Vps35 PF03635.12 EPY51342.1 - 1.6e-239 797.0 16.5 1.9e-239 796.8 11.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribosomal_L9_N PF01281.14 EPY51343.1 - 8.4e-10 37.7 0.1 1.3e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Thioredoxin PF00085.15 EPY51344.1 - 4.1e-05 23.2 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin MVIN PF03023.9 EPY51344.1 - 0.014 13.8 0.3 0.02 13.3 0.2 1.1 1 0 0 1 1 1 0 MviN-like protein CarD_CdnL_TRCF PF02559.11 EPY51345.1 - 0.098 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 CarD-like/TRCF domain UQ_con PF00179.21 EPY51346.1 - 1.4e-37 128.2 0.0 1.7e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EPY51346.1 - 0.042 13.5 0.2 0.08 12.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain Aminotran_3 PF00202.16 EPY51347.1 - 4.1e-98 328.3 0.0 4.8e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 EPY51347.1 - 0.0061 15.6 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EPY51347.1 - 0.015 14.0 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V HbrB PF08539.6 EPY51348.1 - 9.8e-41 139.2 1.0 1.5e-40 138.6 0.7 1.3 1 0 0 1 1 1 1 HbrB-like Glyco_transf_15 PF01793.11 EPY51349.1 - 1.9e-126 421.4 9.4 2.5e-126 421.1 6.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Lactamase_B_2 PF12706.2 EPY51350.1 - 1.9e-14 53.6 0.0 2.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPY51350.1 - 5.9e-11 42.3 0.0 9.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EPY51350.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Gtr1_RagA PF04670.7 EPY51351.1 - 5.1e-70 235.2 0.7 6.5e-70 234.8 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPY51351.1 - 2.9e-05 23.3 0.0 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPY51351.1 - 0.0011 19.4 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EPY51351.1 - 0.0056 15.9 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPY51351.1 - 0.014 15.3 0.0 0.077 12.9 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EPY51351.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.7 EPY51352.1 - 3.9e-34 116.6 1.6 7.1e-34 115.8 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPY51352.1 - 4.9e-30 103.7 1.0 7.5e-30 103.1 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPY51352.1 - 0.003 18.4 0.0 0.0051 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1777 PF08648.7 EPY51353.1 - 2.3e-27 95.8 30.6 2.3e-27 95.8 21.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) AMP-binding PF00501.23 EPY51354.1 - 1.6e-38 132.1 0.0 2.3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPY51354.1 - 3.5e-37 127.6 0.0 5.9e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPY51354.1 - 6.1e-10 38.9 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPY51354.1 - 1.1e-08 35.1 0.0 2.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 EPY51354.1 - 0.00061 19.8 0.0 0.0031 17.5 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPY51354.1 - 0.0069 15.3 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EPY51354.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EPY51354.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase ABC_membrane PF00664.18 EPY51355.1 - 2.7e-105 351.7 38.7 1.4e-53 182.1 10.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPY51355.1 - 5.9e-67 224.1 0.0 1.3e-32 112.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPY51355.1 - 7.7e-13 48.1 5.5 2e-05 23.9 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPY51355.1 - 9.6e-13 48.7 0.1 0.039 13.9 0.1 4.8 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 EPY51355.1 - 1.1e-08 34.1 1.7 0.00036 19.2 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EPY51355.1 - 1.5e-07 31.6 0.0 0.017 15.1 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EPY51355.1 - 2.4e-07 30.1 2.0 0.00094 18.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPY51355.1 - 8.4e-07 29.8 0.0 0.056 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPY51355.1 - 1.4e-05 24.3 0.0 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPY51355.1 - 2.8e-05 23.6 0.0 0.098 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EPY51355.1 - 0.00018 21.1 0.7 1.3 8.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EPY51355.1 - 0.00033 20.5 2.1 0.41 10.5 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EPY51355.1 - 0.00068 19.7 4.3 0.95 9.6 0.1 4.1 2 2 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPY51355.1 - 0.00083 18.8 0.5 0.81 9.0 0.0 3.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EPY51355.1 - 0.002 18.4 1.3 0.28 11.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EPY51355.1 - 0.0028 17.5 0.1 3.8 7.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPY51355.1 - 0.0073 16.6 0.0 7.6 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPY51355.1 - 0.01 14.9 0.7 3.9 6.5 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.12 EPY51355.1 - 0.011 15.5 1.1 1.9 8.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 EPY51355.1 - 0.011 15.4 0.1 1.7 8.4 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 EPY51355.1 - 0.012 15.3 0.1 9.3 5.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPY51355.1 - 0.025 14.4 0.1 7.3 6.5 0.0 3.5 4 0 0 4 4 4 0 AAA domain MobB PF03205.9 EPY51355.1 - 0.045 13.4 0.6 8.5 6.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EPY51355.1 - 0.048 13.1 2.2 7.2 5.9 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain AAA_28 PF13521.1 EPY51355.1 - 0.048 13.6 1.1 3.6 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EPY51355.1 - 0.054 12.1 0.0 2.7 6.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 EPY51355.1 - 0.12 11.2 0.2 10 4.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Ribosomal_L39 PF00832.15 EPY51356.1 - 9.4e-23 79.4 10.5 1.1e-22 79.2 7.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_L13e PF01294.13 EPY51356.1 - 0.12 11.8 1.5 0.13 11.7 1.0 1.0 1 0 0 1 1 1 0 Ribosomal protein L13e DUF2205 PF10224.4 EPY51357.1 - 2e-07 30.4 1.2 2.3e-07 30.2 0.9 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) ATP-synt_D PF01813.12 EPY51357.1 - 0.01 15.4 0.3 0.011 15.3 0.2 1.0 1 0 0 1 1 1 0 ATP synthase subunit D His_kinase PF06580.8 EPY51357.1 - 0.024 14.5 0.5 0.026 14.4 0.3 1.1 1 0 0 1 1 1 0 Histidine kinase Ead_Ea22 PF13935.1 EPY51357.1 - 0.03 14.6 0.1 0.031 14.6 0.1 1.1 1 0 0 1 1 1 0 Ead/Ea22-like protein Tropomyosin PF00261.15 EPY51357.1 - 0.036 13.1 1.5 0.043 12.9 1.0 1.0 1 0 0 1 1 1 0 Tropomyosin bZIP_2 PF07716.10 EPY51357.1 - 0.2 11.5 5.5 0.31 10.8 3.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper ASF1_hist_chap PF04729.8 EPY51358.1 - 1.1e-62 210.2 0.7 1.5e-62 209.8 0.5 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone CobT PF06213.7 EPY51358.1 - 0.14 11.2 26.3 0.21 10.6 18.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EPY51358.1 - 0.6 7.9 33.2 0.66 7.8 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EPY51358.1 - 0.99 8.5 24.4 1.2 8.3 16.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RR_TM4-6 PF06459.7 EPY51358.1 - 4.6 7.0 23.9 5.8 6.7 16.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.7 EPY51358.1 - 5.9 6.0 31.9 6.8 5.8 22.1 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EPY51358.1 - 6.5 5.0 34.2 7.4 4.9 23.7 1.1 1 0 0 1 1 1 0 Daxx Family PDEase_II PF02112.10 EPY51359.1 - 1e-95 320.5 0.1 1.2e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EPY51359.1 - 2.7e-07 30.3 0.1 3.9e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPY51359.1 - 0.038 13.6 0.2 0.082 12.5 0.1 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Clat_adaptor_s PF01217.15 EPY51360.1 - 5.3e-09 35.9 0.1 1.1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain SPRY PF00622.23 EPY51361.1 - 7.5e-17 61.5 0.1 1.4e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain UBX PF00789.15 EPY51362.1 - 2.9e-19 68.9 0.0 5.7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EPY51362.1 - 5.1e-05 22.7 0.5 0.0001 21.7 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EPY51362.1 - 0.0008 19.1 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DDRGK PF09756.4 EPY51362.1 - 0.55 9.6 11.8 0.93 8.8 8.2 1.3 1 0 0 1 1 1 0 DDRGK domain YqfQ PF14181.1 EPY51362.1 - 1 9.3 4.2 1.9 8.5 2.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein DUF612 PF04747.7 EPY51362.1 - 4.3 6.1 10.7 6.8 5.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF612 DUF1682 PF07946.9 EPY51362.1 - 4.4 6.0 9.4 7.2 5.3 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LSM PF01423.17 EPY51363.1 - 9.8e-18 63.4 0.1 1.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain TRAPPC10 PF12584.3 EPY51365.1 - 7.4e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TBD PF12845.2 EPY51365.1 - 0.099 12.2 1.3 19 4.9 0.0 2.7 2 0 0 2 2 2 0 TBD domain Ribosomal_S28e PF01200.13 EPY51366.1 - 3.4e-34 116.4 2.0 3.6e-34 116.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 EPY51367.1 - 3.3e-89 298.3 0.0 5.3e-89 297.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPY51367.1 - 2.9e-46 157.8 0.0 5.1e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPY51367.1 - 1.3e-34 118.6 0.2 4.5e-34 116.8 0.3 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EPY51367.1 - 1.4e-20 73.7 0.0 3.6e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EPY51367.1 - 2.2e-15 56.5 0.6 7.9e-15 54.8 0.4 2.1 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 EPY51367.1 - 0.033 14.0 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPY51367.1 - 0.039 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPY51367.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.2 4 1 1 5 5 5 0 AAA domain SWIB PF02201.13 EPY51368.1 - 3.8e-28 96.9 1.5 4.8e-28 96.6 0.3 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EPY51368.1 - 1.1e-08 34.6 1.0 1.9e-08 33.9 0.7 1.4 1 0 0 1 1 1 1 DEK C terminal domain Sds3 PF08598.6 EPY51368.1 - 0.068 12.6 8.0 0.13 11.7 5.5 1.7 1 1 0 1 1 1 0 Sds3-like zf-C3HC4_3 PF13920.1 EPY51369.1 - 9.6e-07 28.3 10.8 9.6e-07 28.3 7.5 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Yae1_N PF09811.4 EPY51370.1 - 2.7e-08 33.1 5.3 5.1e-08 32.3 3.6 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cytochrom_C PF00034.16 EPY51371.1 - 3.7e-10 40.5 0.1 5.6e-10 39.9 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EPY51371.1 - 7.9e-08 32.3 3.2 8.5e-07 29.0 2.2 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EPY51371.1 - 0.0048 16.3 1.4 0.048 13.1 0.1 2.3 2 1 1 3 3 3 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EPY51371.1 - 0.023 15.0 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Nuc_deoxyrib_tr PF05014.10 EPY51372.1 - 5e-29 100.4 0.0 6.1e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase AMP-binding PF00501.23 EPY51373.1 - 8e-91 304.4 0.0 9.6e-91 304.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPY51373.1 - 5.9e-18 65.5 0.0 1.3e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2523 PF10734.4 EPY51373.1 - 0.056 13.6 1.2 0.13 12.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) B12D PF06522.6 EPY51376.1 - 1.9e-07 30.6 0.1 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit LSM PF01423.17 EPY51377.1 - 2.7e-18 65.2 0.8 3.4e-18 64.9 0.6 1.1 1 0 0 1 1 1 1 LSM domain DUF2986 PF11661.3 EPY51377.1 - 0.39 11.0 0.3 0.39 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Aminotran_1_2 PF00155.16 EPY51378.1 - 4.2e-58 197.0 0.0 5.4e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPY51378.1 - 0.00013 20.8 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPY51378.1 - 0.00035 19.7 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EPY51378.1 - 0.0054 15.3 0.0 0.014 13.9 0.0 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 EPY51378.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GCV_T PF01571.16 EPY51379.1 - 4.2e-13 49.1 0.0 1.3e-10 41.0 0.0 2.1 1 1 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPY51379.1 - 0.00015 21.7 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain IF-2B PF01008.12 EPY51380.1 - 1.3e-85 286.8 0.0 1.8e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pro_isomerase PF00160.16 EPY51381.1 - 4.5e-45 153.6 0.0 7.3e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EPY51381.1 - 1.4e-05 24.4 0.7 3.8e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger Acetyltransf_1 PF00583.19 EPY51382.1 - 1.3e-07 31.5 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPY51382.1 - 4.3e-05 23.5 0.0 6.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY51382.1 - 0.0004 20.0 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EPY51382.1 - 0.0024 18.0 0.0 0.0032 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPY51382.1 - 0.0033 17.5 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPY51382.1 - 0.053 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPY51382.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Epimerase PF01370.16 EPY51383.1 - 6.2e-05 22.5 0.6 0.0082 15.5 0.1 2.0 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY51383.1 - 0.00023 19.9 1.2 0.00079 18.2 1.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPY51383.1 - 0.0011 18.9 0.3 0.041 13.8 0.0 2.1 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPY51383.1 - 0.0045 15.9 0.0 0.0052 15.7 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPY51383.1 - 0.0058 15.5 0.3 0.0086 15.0 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EPY51384.1 - 9.1e-32 110.7 0.1 1.1e-31 110.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPY51384.1 - 1.5e-31 109.5 0.5 1.9e-31 109.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY51384.1 - 2.4e-14 53.4 0.2 3.4e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY51384.1 - 0.0056 16.7 0.8 0.011 15.6 0.6 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY51384.1 - 0.02 14.3 0.9 0.26 10.6 0.6 2.4 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPY51384.1 - 0.028 14.0 0.4 0.043 13.4 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPY51384.1 - 0.21 10.5 1.5 0.43 9.4 0.5 1.8 1 1 1 2 2 2 0 Male sterility protein bZIP_1 PF00170.16 EPY51385.1 - 1.3e-08 34.6 11.9 1.9e-08 34.1 8.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPY51385.1 - 3.6e-08 33.1 12.0 5.7e-08 32.4 8.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPY51385.1 - 0.021 15.1 11.3 0.033 14.4 7.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2514 PF10721.4 EPY51385.1 - 0.12 12.0 5.3 0.14 11.8 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GCN5L1 PF06320.8 EPY51385.1 - 0.44 10.3 6.5 0.93 9.3 4.5 1.6 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Ribosomal_S20p PF01649.13 EPY51385.1 - 0.78 10.1 5.2 1.1 9.6 3.6 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 DUF16 PF01519.11 EPY51385.1 - 0.81 9.9 4.2 1.2 9.3 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.5 EPY51385.1 - 0.84 9.7 4.5 1.3 9.1 3.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 EPY51385.1 - 0.86 9.6 7.5 0.42 10.6 1.7 2.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Ribosomal_L2_C PF03947.13 EPY51386.1 - 1.1e-74 248.3 14.1 3.2e-37 127.2 2.1 2.3 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPY51386.1 - 5e-15 55.2 0.0 1.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SpoA PF01052.15 EPY51386.1 - 0.0035 16.8 0.1 2.6 7.7 0.0 2.3 2 0 0 2 2 2 2 Surface presentation of antigens (SPOA) Guanylate_cyc_2 PF09778.4 EPY51386.1 - 0.034 13.3 0.0 8.8 5.4 0.0 2.4 2 1 1 3 3 3 0 Guanylylate cyclase X_fast-SP_rel PF06669.6 EPY51386.1 - 1.2 9.1 4.5 21 5.1 0.3 2.6 2 0 0 2 2 2 0 Xylella fastidiosa surface protein related Aldo_ket_red PF00248.16 EPY51387.1 - 1.1e-69 234.3 0.0 1.3e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EPY51388.1 - 6.9e-30 103.7 0.5 1.8e-29 102.4 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY51388.1 - 5.6e-05 22.9 11.4 0.00011 22.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_Glu_race PF01177.17 EPY51389.1 - 7e-26 91.4 0.1 8.1e-26 91.2 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Cro PF09048.5 EPY51389.1 - 0.018 14.6 0.3 0.041 13.5 0.0 1.7 2 0 0 2 2 2 0 Cro Allantoicase PF03561.10 EPY51390.1 - 6.4e-101 334.1 0.0 8.7e-54 181.1 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DUF999 PF06198.6 EPY51391.1 - 6.8e-11 42.1 4.3 5.2e-10 39.2 2.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF999) FTR1 PF03239.9 EPY51392.1 - 2.6e-95 318.8 9.4 3.4e-95 318.5 6.5 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Cytochrom_C_asm PF01578.15 EPY51392.1 - 0.0004 20.0 4.7 0.0072 15.8 1.7 2.4 2 0 0 2 2 2 2 Cytochrome C assembly protein DUF221 PF02714.10 EPY51392.1 - 0.018 13.8 1.3 0.18 10.6 0.9 2.3 1 1 0 1 1 1 0 Domain of unknown function DUF221 Cu-oxidase PF00394.17 EPY51393.1 - 6.5e-45 152.8 7.1 1.2e-41 142.2 0.9 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPY51393.1 - 1.3e-40 138.1 8.0 1.9e-39 134.3 0.5 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EPY51393.1 - 9.6e-35 118.8 7.3 8.7e-34 115.7 1.3 3.6 4 1 1 5 5 5 1 Multicopper oxidase DJ-1_PfpI PF01965.19 EPY51394.1 - 9.1e-15 54.3 0.0 4.8e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Ribonuc_red_lgC PF02867.10 EPY51395.1 - 7e-213 708.0 0.0 8.8e-213 707.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EPY51395.1 - 6.7e-23 80.2 0.0 1.8e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EPY51395.1 - 3.2e-15 56.3 0.0 1.1e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain Ras PF00071.17 EPY51396.1 - 5.4e-56 188.4 0.0 6.4e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY51396.1 - 1.8e-14 54.2 0.0 3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY51396.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPY51396.1 - 0.0035 16.5 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPY51396.1 - 0.061 12.4 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4536 PF15055.1 EPY51397.1 - 2.3e-06 27.5 2.5 5.7e-06 26.3 1.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) TRP PF06011.7 EPY51398.1 - 4.5e-94 315.4 31.8 6.2e-94 315.0 22.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPY51398.1 - 3.2e-38 130.9 1.5 4.7e-38 130.4 1.1 1.3 1 0 0 1 1 1 1 ML-like domain DEAD PF00270.24 EPY51399.1 - 5.6e-45 152.8 0.0 1.1e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPY51399.1 - 5.3e-22 77.1 0.8 1.2e-21 75.9 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPY51399.1 - 6.6e-14 51.5 0.0 1.6e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SH2_2 PF14633.1 EPY51400.1 - 9.1e-100 332.2 0.1 4e-99 330.1 0.1 2.2 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 EPY51400.1 - 8e-49 164.5 7.5 8e-49 164.5 5.2 3.5 3 1 1 4 4 4 1 Death-like domain of SPT6 YqgF PF14639.1 EPY51400.1 - 2.9e-48 163.2 0.0 2.8e-47 160.0 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EPY51400.1 - 4.7e-46 155.1 0.1 1.9e-45 153.1 0.0 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EPY51400.1 - 1.4e-40 138.0 1.9 1.4e-40 138.0 1.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EPY51400.1 - 1.9e-17 63.1 17.7 1.9e-17 63.1 12.3 4.7 2 2 2 4 4 4 1 Acidic N-terminal SPT6 S1 PF00575.18 EPY51400.1 - 3.9e-05 23.6 0.1 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 S1 RNA binding domain SH2 PF00017.19 EPY51400.1 - 0.0002 21.1 0.0 0.00073 19.3 0.0 2.1 1 0 0 1 1 1 1 SH2 domain Tex_N PF09371.5 EPY51400.1 - 0.00022 20.6 3.3 0.001 18.4 0.0 3.4 4 0 0 4 4 4 1 Tex-like protein N-terminal domain HHH_3 PF12836.2 EPY51400.1 - 0.016 15.0 0.1 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif MRC1 PF09444.5 EPY51401.1 - 9.2e-32 110.3 16.0 9.2e-32 110.3 11.1 5.3 4 2 1 6 6 6 1 MRC1-like domain Ribosomal_S25 PF03297.10 EPY51402.1 - 8.7e-35 118.9 1.2 9.6e-35 118.8 0.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EPY51402.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Ftsk gamma domain UPF0160 PF03690.8 EPY51403.1 - 2.8e-121 404.8 0.0 3.2e-121 404.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF2611 PF11022.3 EPY51403.1 - 0.08 13.0 0.5 7.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Rsbr_N PF08678.5 EPY51403.1 - 0.14 12.0 0.4 0.57 10.0 0.1 2.0 2 0 0 2 2 2 0 Rsbr N terminal CTP_transf_2 PF01467.21 EPY51404.1 - 6.5e-08 32.7 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase DUF1380 PF07128.7 EPY51404.1 - 0.032 14.0 0.0 0.083 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) DEAD PF00270.24 EPY51405.1 - 6.3e-18 64.8 0.0 1.2e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPY51405.1 - 4.9e-09 36.2 0.8 8.7e-07 28.9 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPY51405.1 - 7e-08 32.2 0.2 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EPY51405.1 - 0.00034 19.9 0.0 0.012 14.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein zf-CCHC PF00098.18 EPY51406.1 - 3.3e-08 33.0 31.4 0.019 14.8 0.3 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 EPY51406.1 - 0.00046 19.8 30.8 0.15 11.7 0.5 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EPY51406.1 - 0.04 13.4 24.7 0.76 9.3 1.7 4.4 2 1 1 4 4 4 0 Zinc knuckle zf-C2H2 PF00096.21 EPY51407.1 - 2.7e-09 36.7 9.6 0.00013 22.1 0.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPY51407.1 - 2e-06 27.8 12.4 4.7e-06 26.6 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPY51407.1 - 7.1e-06 25.9 8.7 0.015 15.5 0.1 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger Mem_trans PF03547.13 EPY51407.1 - 0.32 9.2 1.3 0.6 8.3 0.9 1.4 1 0 0 1 1 1 0 Membrane transport protein zf-H2C2_5 PF13909.1 EPY51407.1 - 1.3 9.3 7.1 11 6.5 0.8 3.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF1687 PF07955.6 EPY51408.1 - 2.3e-18 66.4 0.4 3.7e-18 65.7 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) FPL PF09758.4 EPY51408.1 - 0.072 12.8 0.5 4.9 6.9 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein ATP-synt_G PF04718.10 EPY51408.1 - 0.09 13.4 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit Peptidase_A22B PF04258.8 EPY51409.1 - 7.9e-68 229.0 9.5 2.8e-62 210.8 6.2 2.0 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 EPY51409.1 - 2.5e-05 23.5 12.8 0.00084 18.5 8.7 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) POP1 PF06978.6 EPY51410.1 - 1.4e-56 191.1 3.9 3.1e-56 189.9 2.7 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EPY51410.1 - 4.6e-31 106.5 1.2 1e-30 105.3 0.8 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain TYW3 PF02676.9 EPY51411.1 - 2.7e-63 212.8 0.0 3.1e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 CENP-O PF09496.5 EPY51412.1 - 7.4e-12 45.3 0.5 1.9e-11 43.9 0.1 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DIOX_N PF14226.1 EPY51413.1 - 1.2e-23 83.8 0.1 9.8e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPY51413.1 - 2.9e-19 69.2 0.0 5.6e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hydrolase_3 PF08282.7 EPY51414.1 - 4.9e-36 124.5 0.0 1.2e-28 100.3 0.0 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EPY51414.1 - 9.9e-08 31.5 0.0 0.00092 18.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 EPY51414.1 - 0.0046 17.1 0.0 0.096 12.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY51414.1 - 0.045 14.1 0.8 4.5 7.6 0.5 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EPY51415.1 - 8.9e-30 103.4 4.8 1.6e-29 102.5 3.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY51415.1 - 6.3e-05 22.7 4.5 6.3e-05 22.7 3.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_11 PF08241.7 EPY51416.1 - 4e-20 72.1 0.0 9.6e-20 70.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY51416.1 - 4.5e-15 55.5 0.0 6.5e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY51416.1 - 3.4e-13 49.6 0.0 4.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY51416.1 - 3.5e-12 46.5 0.0 8.3e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY51416.1 - 1.5e-10 41.4 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPY51416.1 - 1.5e-09 37.2 0.0 2.9e-09 36.3 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EPY51416.1 - 7.8e-09 36.1 0.0 1.4e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPY51416.1 - 4.6e-05 23.1 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EPY51416.1 - 5.7e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPY51416.1 - 0.00018 20.4 0.0 0.00023 20.1 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EPY51416.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EPY51416.1 - 0.014 14.4 0.0 2.9 6.9 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase Methyltransf_29 PF03141.11 EPY51416.1 - 0.019 13.2 0.0 0.035 12.4 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPD52 PF04201.10 EPY51416.1 - 0.027 14.2 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family MetW PF07021.7 EPY51416.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EPY51416.1 - 0.096 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DIL PF01843.14 EPY51417.1 - 1.4e-11 44.2 0.6 1.4e-10 41.0 0.4 2.4 1 1 0 1 1 1 1 DIL domain HIG_1_N PF04588.8 EPY51418.1 - 4.5e-18 64.7 0.1 5.8e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region tRNA-synt_2b PF00587.20 EPY51419.1 - 2.6e-23 82.4 0.0 4.6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPY51419.1 - 1.8e-12 47.1 0.0 3.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain PseudoU_synth_1 PF01416.15 EPY51420.1 - 3.3e-30 104.6 0.0 5e-17 62.2 0.0 3.2 3 0 0 3 3 3 2 tRNA pseudouridine synthase zf-Mss51 PF13824.1 EPY51421.1 - 1.6e-19 69.4 2.0 3.7e-19 68.3 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 EPY51421.1 - 0.018 14.5 0.1 0.061 12.9 0.1 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PS_Dcarbxylase PF02666.10 EPY51422.1 - 5.8e-69 231.4 0.0 2.1e-68 229.6 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Sds3 PF08598.6 EPY51423.1 - 5.4e-22 78.3 11.7 7.4e-22 77.8 8.1 1.2 1 0 0 1 1 1 1 Sds3-like APP_E2 PF12925.2 EPY51423.1 - 0.058 12.9 8.5 0.1 12.1 5.9 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein IncA PF04156.9 EPY51423.1 - 0.84 9.2 11.2 1.6 8.2 7.7 1.5 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EPY51423.1 - 0.96 7.7 4.5 1.4 7.2 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) OmpH PF03938.9 EPY51423.1 - 1 9.2 6.6 2.4 8.0 4.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_pol_Rpb1_4 PF05000.12 EPY51423.1 - 1.5 8.5 4.0 2.1 8.0 0.3 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 4 Cyt-b5 PF00173.23 EPY51424.1 - 1.1e-10 41.1 0.0 1.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain VEFS-Box PF09733.4 EPY51424.1 - 0.094 12.3 0.4 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Kei1 PF08552.6 EPY51426.1 - 5.6e-36 123.9 17.7 5.4e-30 104.4 7.9 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 RNA_pol PF00940.14 EPY51427.1 - 1.4e-155 517.7 0.0 2e-155 517.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EPY51427.1 - 1e-61 209.0 0.0 1.7e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PH_4 PF15404.1 EPY51428.1 - 2e-26 92.6 5.3 5.8e-20 71.6 0.2 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain PH PF00169.24 EPY51428.1 - 1.9e-08 34.4 3.3 0.0037 17.4 0.3 3.1 2 1 0 2 2 2 2 PH domain PH_6 PF15406.1 EPY51428.1 - 0.00036 20.5 0.0 0.9 9.6 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain Spo7_2_N PF15407.1 EPY51428.1 - 0.00045 19.6 0.1 0.0016 17.8 0.0 2.0 1 0 0 1 1 1 1 Sporulation protein family 7 PH_9 PF15410.1 EPY51428.1 - 0.0019 18.3 0.3 0.067 13.3 0.0 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain eIF-5a PF01287.15 EPY51429.1 - 3.3e-26 91.0 0.3 4.7e-26 90.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EPY51429.1 - 0.00011 21.7 1.4 0.00011 21.7 1.0 2.2 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EPY51429.1 - 0.0069 16.2 0.1 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain GFO_IDH_MocA PF01408.17 EPY51430.1 - 4e-22 78.9 0.0 6.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPY51430.1 - 5.6e-17 61.5 0.0 8.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EPY51430.1 - 6.8e-05 23.2 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EPY51430.1 - 0.047 13.9 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 EPY51430.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain F420_oxidored PF03807.12 EPY51430.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_17 PF00332.13 EPY51431.1 - 1.7e-34 119.2 0.6 4.8e-34 117.8 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Lung_7-TM_R PF06814.8 EPY51432.1 - 1.2e-76 257.4 23.4 1.5e-76 257.1 16.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor POT1 PF02765.12 EPY51433.1 - 5.9e-15 55.4 0.0 1.6e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Flavokinase PF01687.12 EPY51433.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Riboflavin kinase TIG PF01833.19 EPY51434.1 - 2.8e-13 49.6 1.5 7.9e-13 48.2 1.0 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 EPY51434.1 - 3e-13 48.8 1.5 1.1e-05 24.9 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EPY51434.1 - 9.2e-13 48.3 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPY51434.1 - 8.1e-12 44.9 2.0 7.8e-07 29.1 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPY51434.1 - 1.2e-08 35.2 0.2 3.9e-07 30.4 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPY51434.1 - 3.6e-08 32.8 0.4 0.0046 17.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Arm PF00514.18 EPY51435.1 - 2.1e-14 52.7 6.9 0.0001 21.9 0.0 7.7 7 1 1 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPY51435.1 - 5.4e-12 45.8 0.2 0.01 16.0 0.0 5.5 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EPY51435.1 - 8.6e-06 25.4 12.9 0.0079 16.1 0.0 6.8 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 EPY51435.1 - 4.7e-05 23.7 5.0 4.6 7.8 0.0 5.9 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPY51435.1 - 0.07 13.5 3.0 0.23 11.8 0.2 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EPY51435.1 - 1.7 8.5 6.4 6.4 6.7 0.1 4.7 4 1 2 6 6 6 0 V-ATPase subunit H WD40 PF00400.27 EPY51436.1 - 1.4e-28 97.6 5.9 1.4e-05 24.7 0.0 7.2 7 1 1 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EPY51436.1 - 7.4e-06 25.8 0.3 0.036 13.7 0.1 3.5 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EPY51436.1 - 0.067 12.9 0.1 12 5.7 0.0 2.9 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MgsA_C PF12002.3 EPY51437.1 - 2.9e-54 183.2 0.0 4.1e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EPY51437.1 - 1.6e-15 57.4 0.1 2.5e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPY51437.1 - 1.9e-12 46.7 0.0 7.4e-12 44.8 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPY51437.1 - 3.7e-08 33.1 0.1 2.7e-07 30.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EPY51437.1 - 5.5e-07 29.2 0.0 0.00019 20.9 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 EPY51437.1 - 4e-06 26.9 0.1 0.00051 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPY51437.1 - 2.9e-05 23.9 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPY51437.1 - 3.7e-05 23.8 0.4 0.0015 18.7 0.3 2.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPY51437.1 - 0.00011 21.0 0.0 0.00063 18.5 0.0 1.9 1 1 1 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EPY51437.1 - 0.0003 19.8 0.0 0.00049 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EPY51437.1 - 0.00036 20.5 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EPY51437.1 - 0.00095 18.3 0.1 0.64 9.1 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPY51437.1 - 0.0018 17.9 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EPY51437.1 - 0.0031 17.3 0.2 0.9 9.3 0.1 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.1 EPY51437.1 - 0.0038 16.8 0.1 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit ABC_tran PF00005.22 EPY51437.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EPY51437.1 - 0.013 15.1 0.0 3.4 7.3 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EPY51437.1 - 0.02 14.0 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_3 PF07726.6 EPY51437.1 - 0.022 14.3 0.0 0.069 12.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EPY51437.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 EPY51437.1 - 0.03 13.0 0.1 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PhoH PF02562.11 EPY51437.1 - 0.036 13.3 0.2 0.57 9.3 0.0 2.2 1 1 1 2 2 2 0 PhoH-like protein AAA_17 PF13207.1 EPY51437.1 - 0.038 14.8 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 EPY51437.1 - 0.039 12.4 0.0 0.067 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RNA_helicase PF00910.17 EPY51437.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.1 EPY51437.1 - 0.072 11.5 0.1 0.15 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EPY51437.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EPY51437.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPY51437.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPY51437.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EPY51437.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EPY51437.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EPY51437.1 - 0.17 11.4 0.1 0.51 9.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EPY51438.1 - 3.4e-22 78.7 0.0 6.3e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY51438.1 - 1.4e-10 40.8 0.0 5.3e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EPY51438.1 - 8.5e-10 39.0 3.7 2.1e-09 37.8 2.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 EPY51438.1 - 1.7e-06 28.0 0.7 1.7e-06 28.0 0.5 1.9 2 0 0 2 2 2 1 DNA replication factor CDT1 like Mit_ribos_Mrp51 PF11709.3 EPY51439.1 - 1.4e-12 47.5 0.4 9.7e-12 44.7 0.3 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Glyco_hydro_67C PF07477.7 EPY51439.1 - 0.02 14.3 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus RPAP2_Rtr1 PF04181.8 EPY51441.1 - 5e-16 58.5 2.1 9e-16 57.7 1.4 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Sec20 PF03908.8 EPY51442.1 - 5e-28 96.6 3.1 6.3e-28 96.3 1.0 1.9 2 0 0 2 2 2 1 Sec20 GDI PF00996.13 EPY51442.1 - 0.0006 18.2 0.1 0.00073 17.9 0.1 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Cys_Met_Meta_PP PF01053.15 EPY51443.1 - 4.7e-58 196.3 0.0 1e-57 195.1 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPY51443.1 - 5.7e-06 25.5 0.0 8.6e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPY51443.1 - 0.0045 15.7 0.0 0.0089 14.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V O-ag_pol_Wzy PF14296.1 EPY51443.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy B3_4 PF03483.12 EPY51444.1 - 5.8e-22 77.9 0.0 9.4e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EPY51444.1 - 2.7e-17 62.3 0.0 3.2e-14 52.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Ribosomal_L13 PF00572.13 EPY51445.1 - 1.6e-26 92.8 0.1 4.2e-26 91.4 0.0 1.7 3 0 0 3 3 3 1 Ribosomal protein L13 GTP_EFTU PF00009.22 EPY51446.1 - 3.8e-57 192.7 0.1 7.5e-57 191.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPY51446.1 - 2.2e-36 123.9 0.0 6.4e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPY51446.1 - 1.1e-16 60.7 1.2 3.2e-16 59.2 0.8 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPY51446.1 - 7.1e-05 22.3 0.3 0.00019 21.0 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPY51446.1 - 0.0014 18.5 0.5 0.0044 16.9 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.17 EPY51447.1 - 3.8e-15 55.2 0.0 4.7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51447.1 - 8.6e-13 48.0 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51447.1 - 1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPY51447.1 - 0.004 16.9 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Ribosomal_L34e PF01199.13 EPY51448.1 - 9.7e-38 128.3 1.1 1.3e-37 127.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e zf-C3HC4_4 PF15227.1 EPY51449.1 - 3.1e-06 26.9 3.7 3.1e-06 26.9 2.5 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EPY51449.1 - 3.7e-05 23.2 10.1 5.7e-05 22.7 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY51449.1 - 0.00013 21.6 9.0 0.00027 20.5 6.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPY51449.1 - 0.00013 21.9 10.0 0.00026 20.9 5.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY51449.1 - 0.0021 17.8 8.1 0.0027 17.4 5.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPY51449.1 - 0.0035 16.9 10.3 0.019 14.5 7.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPY51449.1 - 0.0058 16.3 2.1 0.015 15.0 0.2 2.4 1 1 1 2 2 2 1 RING-type zinc-finger GLF PF03275.8 EPY51449.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-galactopyranose mutase Pkinase PF00069.20 EPY51450.1 - 4.2e-68 229.2 0.0 6.1e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51450.1 - 7.4e-30 103.8 0.0 1.5e-29 102.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51450.1 - 1.2e-05 24.4 1.4 0.046 12.6 0.0 2.8 2 1 0 3 3 3 2 Kinase-like APH PF01636.18 EPY51450.1 - 0.0055 16.4 0.0 3.1 7.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPY51450.1 - 0.008 15.2 0.1 0.017 14.2 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPY51450.1 - 0.054 12.8 3.9 0.43 9.9 2.7 2.1 1 1 0 1 1 1 0 RIO1 family DUF3317 PF11779.3 EPY51451.1 - 1.8e-16 59.2 2.5 2.4e-16 58.8 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Tmemb_18A PF09771.4 EPY51451.1 - 0.014 15.3 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 188 Glyco_hydro_47 PF01532.15 EPY51452.1 - 4e-130 434.5 0.0 4.9e-130 434.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.22 EPY51453.1 - 5.4e-18 64.9 0.0 6.6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPY51453.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Metallophos PF00149.23 EPY51454.1 - 3.8e-16 59.0 0.1 6.3e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPY51454.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3521 PF12035.3 EPY51454.1 - 0.063 13.1 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) Glyco_transf_20 PF00982.16 EPY51456.1 - 6.9e-156 519.4 1.4 9.6e-156 518.9 0.9 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPY51456.1 - 4.9e-82 274.3 0.0 8.9e-82 273.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PIP5K PF01504.13 EPY51457.1 - 3.7e-84 281.7 0.1 5.1e-84 281.3 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase polyprenyl_synt PF00348.12 EPY51458.1 - 0.0013 17.6 0.4 0.03 13.1 0.2 2.1 1 1 0 1 1 1 1 Polyprenyl synthetase COQ9 PF08511.6 EPY51460.1 - 1.1e-27 95.3 0.2 1.6e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 COQ9 Med9 PF07544.8 EPY51460.1 - 0.054 13.2 0.0 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ER PF01133.12 EPY51461.1 - 2.8e-16 59.1 0.1 3.4e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_S10 PF00450.17 EPY51462.1 - 1.7e-130 435.9 0.4 2.4e-130 435.4 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPY51462.1 - 0.0095 15.8 0.0 0.18 11.6 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 EPY51463.1 - 1.4e-47 161.9 0.0 1.6e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LNS2 PF08235.8 EPY51463.1 - 0.098 12.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) FA_hydroxylase PF04116.8 EPY51464.1 - 5.7e-08 33.1 25.0 7.4e-08 32.7 15.2 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EPY51464.1 - 0.081 12.9 0.2 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.17 EPY51466.1 - 9.6e-41 137.2 0.2 1.6e-16 59.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51466.1 - 2e-30 104.5 0.3 1.7e-11 43.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51466.1 - 5.6e-22 77.3 0.0 2.4e-07 30.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EPY51466.1 - 1.7e-10 40.9 0.0 5.4e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.1 EPY51466.1 - 2.3e-06 27.2 0.2 0.64 9.8 0.1 3.7 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPY51466.1 - 0.057 13.2 0.2 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Histone PF00125.19 EPY51467.1 - 7.8e-26 90.0 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY51467.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.22 EPY51468.1 - 9.4e-61 201.5 3.2 9.9e-23 79.6 0.2 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3411 PF11891.3 EPY51468.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3411) Ureidogly_hydro PF04115.7 EPY51469.1 - 2.3e-44 150.6 0.0 2.7e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Polysacc_deac_1 PF01522.16 EPY51470.1 - 2.7e-17 62.5 0.0 3.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase MutL_C PF08676.6 EPY51471.1 - 2.5e-26 91.9 0.0 6.4e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EPY51471.1 - 9.9e-24 83.0 0.0 2.4e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPY51471.1 - 2.9e-13 49.6 0.5 2.9e-13 49.6 0.3 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPY51471.1 - 1.7e-12 47.0 0.1 4.3e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Apc4 PF12896.2 EPY51472.1 - 3.5e-38 131.0 2.4 5.9e-38 130.2 0.7 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EPY51472.1 - 1.8e-09 36.9 0.0 6.1e-08 32.0 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.1 EPY51472.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain RhoGEF PF00621.15 EPY51472.1 - 0.016 15.0 1.5 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 RhoGEF domain Tox-PL PF15644.1 EPY51472.1 - 0.19 12.4 0.0 0.4 11.4 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 1 DUF3510 PF12022.3 EPY51472.1 - 0.2 11.7 2.2 0.29 11.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) CPSF_A PF03178.10 EPY51473.1 - 2.4e-89 299.6 0.1 1.7e-88 296.8 0.0 2.3 2 1 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EPY51473.1 - 4.3e-65 219.7 0.0 8.3e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 EPY51473.1 - 0.045 13.3 0.1 0.68 9.5 0.0 2.8 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Ribosomal_S2 PF00318.15 EPY51474.1 - 2.9e-42 144.2 0.1 3.6e-21 75.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Rep_fac_C PF08542.6 EPY51475.1 - 2.6e-22 78.6 0.5 1.6e-21 76.0 0.2 2.5 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPY51475.1 - 3.5e-18 65.7 1.1 1.8e-15 56.9 0.1 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 EPY51475.1 - 6.4e-18 65.2 0.1 1.3e-17 64.1 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPY51475.1 - 1.1e-10 40.8 0.0 1.9e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPY51475.1 - 2.5e-06 27.6 1.5 0.045 13.8 0.0 2.8 2 1 1 3 3 3 2 AAA domain DNA_pol3_delta PF06144.8 EPY51475.1 - 1.7e-05 24.4 0.2 3.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EPY51475.1 - 2e-05 24.4 0.0 5.3e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EPY51475.1 - 4.2e-05 22.5 0.0 7.6e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 EPY51475.1 - 7.1e-05 22.4 0.5 0.00056 19.5 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY51475.1 - 8e-05 22.6 0.0 0.00018 21.5 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.1 EPY51475.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EPY51475.1 - 0.00014 21.0 0.0 0.00046 19.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EPY51475.1 - 0.0087 15.6 0.3 0.016 14.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPY51475.1 - 0.009 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EPY51475.1 - 0.0096 15.5 0.3 0.2 11.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPY51475.1 - 0.011 15.1 0.3 0.061 12.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPY51475.1 - 0.017 14.8 0.2 0.11 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 EPY51475.1 - 0.022 14.2 0.2 0.2 11.1 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.16 EPY51475.1 - 0.026 13.6 0.0 0.14 11.3 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPY51475.1 - 0.031 13.9 0.0 0.097 12.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EPY51475.1 - 0.031 13.6 0.0 0.08 12.3 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 EPY51475.1 - 0.042 13.2 0.6 3.7 6.8 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain ResIII PF04851.10 EPY51475.1 - 0.08 12.7 0.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EPY51475.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase HATPase_c PF02518.21 EPY51476.1 - 7.2e-26 90.0 0.0 1.6e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPY51476.1 - 1.9e-19 69.7 0.0 6.5e-19 68.0 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPY51476.1 - 9.3e-17 60.7 0.0 2.2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 EPY51476.1 - 1.4e-10 40.7 0.0 3.7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 EPY51476.1 - 3.4e-10 40.1 0.0 1.1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PAS_9 PF13426.1 EPY51476.1 - 2.4e-06 27.8 0.0 6.5e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain NACHT PF05729.7 EPY51476.1 - 4.7e-05 23.1 0.0 0.00017 21.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain GAF_3 PF13492.1 EPY51476.1 - 4.7e-05 23.4 0.1 0.00012 22.1 0.1 1.7 1 0 0 1 1 1 1 GAF domain PAS_3 PF08447.6 EPY51476.1 - 0.00046 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 EPY51476.1 - 0.0015 19.0 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 GAF domain AAA_14 PF13173.1 EPY51476.1 - 0.0018 18.1 0.2 0.26 11.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPY51476.1 - 0.0035 17.4 0.0 0.021 14.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPY51476.1 - 0.012 15.9 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA PF00004.24 EPY51476.1 - 0.05 13.8 0.1 0.42 10.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPY51476.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 NTPase GAF PF01590.21 EPY51476.1 - 0.058 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 GAF domain MobB PF03205.9 EPY51476.1 - 0.12 12.0 0.0 0.42 10.3 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EPY51476.1 - 0.14 11.6 0.0 0.91 8.9 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 EPY51476.1 - 0.43 9.3 0.0 0.78 8.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Gly_transf_sug PF04488.10 EPY51477.1 - 0.073 13.4 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif tRNA-synt_1g PF09334.6 EPY51478.1 - 5.6e-107 357.7 0.6 9.2e-107 357.0 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPY51478.1 - 3.3e-20 71.6 0.1 1.9e-11 42.7 0.0 3.0 1 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EPY51478.1 - 3e-07 29.8 0.1 0.00022 20.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EPY51478.1 - 0.013 14.1 0.6 0.021 13.5 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) NYD-SP28 PF14772.1 EPY51478.1 - 0.22 11.6 1.0 0.34 11.0 0.1 1.8 2 0 0 2 2 2 0 Sperm tail DNA_pol_E_B PF04042.11 EPY51479.1 - 4.6e-46 156.7 0.2 6e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4064 PF13273.1 EPY51480.1 - 0.097 12.7 0.6 0.13 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1206 PF06724.6 EPY51480.1 - 0.19 11.4 4.4 2.2 8.1 3.1 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) Alpha_GJ PF03229.8 EPY51480.1 - 0.96 9.7 8.3 1.4 9.3 5.7 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J YchF-GTPase_C PF06071.8 EPY51481.1 - 1.1e-36 124.4 0.3 2.8e-36 123.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPY51481.1 - 3.5e-14 52.7 0.0 2.1e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY51481.1 - 3.1e-05 23.3 0.0 6.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 EPY51481.1 - 0.011 15.9 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPY51481.1 - 0.035 14.0 0.0 0.13 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EPY51481.1 - 0.043 12.5 0.0 0.084 11.6 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 EPY51481.1 - 0.051 14.3 0.1 0.52 11.1 0.1 2.6 1 1 0 1 1 1 0 AAA domain Dna2 PF08696.6 EPY51481.1 - 0.069 12.4 0.1 0.23 10.7 0.0 1.9 2 1 0 2 2 2 0 DNA replication factor Dna2 MobB PF03205.9 EPY51481.1 - 0.11 12.1 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0029 PF01205.14 EPY51482.1 - 2.6e-30 104.3 0.1 4.3e-30 103.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EPY51482.1 - 3e-11 43.2 1.9 1e-09 38.2 1.3 2.7 1 1 0 1 1 1 1 RWD domain Alpha-amylase PF00128.19 EPY51483.1 - 6.2e-62 209.8 0.2 8.1e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPY51483.1 - 0.00028 20.8 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EPY51483.1 - 0.0025 16.7 0.2 0.0037 16.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 hDGE_amylase PF14701.1 EPY51483.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Herpes_BLLF1 PF05109.8 EPY51484.1 - 0.093 10.6 7.3 0.1 10.5 5.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Pkinase PF00069.20 EPY51485.1 - 1.3e-61 208.0 0.0 1.4e-39 135.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51485.1 - 2.3e-26 92.4 0.0 1.6e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPY51485.1 - 4e-05 22.7 0.0 0.00034 19.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Response_reg PF00072.19 EPY51485.1 - 0.00061 19.7 0.2 0.0016 18.3 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 EPY51485.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 PAS fold APH PF01636.18 EPY51485.1 - 0.15 11.7 0.1 0.78 9.4 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Met_10 PF02475.11 EPY51486.1 - 6.5e-70 234.8 0.0 9.3e-70 234.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 EPY51486.1 - 0.0025 16.7 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase UPF0300 PF08594.5 EPY51487.1 - 2.3e-74 248.9 2.3 3.6e-74 248.3 1.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Acyl_transf_1 PF00698.16 EPY51488.1 - 5.9e-19 68.5 0.0 9.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ubiquitin PF00240.18 EPY51489.1 - 1.3e-34 117.4 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EPY51489.1 - 1.2e-29 101.6 11.4 1.8e-29 101.0 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EPY51489.1 - 4.8e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPY51489.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPY51489.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPY51489.1 - 0.0047 16.7 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPY51489.1 - 0.0089 16.1 0.1 0.01 16.0 0.1 1.2 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPY51489.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EPY51489.1 - 0.17 10.1 0.5 4.3 5.5 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EPY51489.1 - 0.28 11.0 2.0 1.3 8.8 1.4 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 EPY51489.1 - 0.71 9.2 4.7 1.1 8.6 3.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Iso_dh PF00180.15 EPY51490.1 - 1.6e-80 270.6 0.0 1.9e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HECT PF00632.20 EPY51491.1 - 2.9e-93 312.4 0.1 4e-93 312.0 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPY51491.1 - 4.2e-34 116.0 21.4 1.7e-11 43.7 3.7 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EPY51491.1 - 7.6e-17 60.9 0.3 2e-16 59.5 0.2 1.8 1 0 0 1 1 1 1 C2 domain SKG6 PF08693.5 EPY51492.1 - 8.3e-10 37.8 1.2 1.9e-09 36.6 0.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ASFV_J13L PF05568.6 EPY51492.1 - 0.00049 19.6 6.6 0.00049 19.6 4.6 3.4 2 1 1 3 3 3 1 African swine fever virus J13L protein DUF4448 PF14610.1 EPY51492.1 - 0.002 17.6 0.3 0.0053 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Rax2 PF12768.2 EPY51492.1 - 0.0037 16.5 6.3 0.0096 15.1 4.4 1.7 1 1 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.1 EPY51492.1 - 0.004 16.8 0.0 0.004 16.8 0.0 2.8 2 1 0 2 2 2 1 TMEM154 protein family SCF PF02404.10 EPY51492.1 - 0.006 15.8 0.5 0.006 15.8 0.4 1.8 2 0 0 2 2 2 1 Stem cell factor Mid2 PF04478.7 EPY51492.1 - 7.1 6.0 14.5 0.026 13.9 1.9 2.7 1 1 2 3 3 3 0 Mid2 like cell wall stress sensor zinc_ribbon_6 PF14599.1 EPY51493.1 - 1.8e-24 85.2 4.8 1.8e-24 85.2 3.4 4.3 4 2 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EPY51493.1 - 1.5e-13 50.6 30.0 1.5e-13 50.6 20.8 4.6 3 1 1 4 4 4 2 CHY zinc finger zf-RING_2 PF13639.1 EPY51493.1 - 2.2e-07 30.6 8.6 2.2e-07 30.6 5.9 5.0 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY51493.1 - 5e-06 26.0 7.0 5e-06 26.0 4.9 6.3 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY51493.1 - 2e-05 24.4 4.3 2e-05 24.4 3.0 6.0 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY51493.1 - 8.1e-05 22.2 7.3 8.1e-05 22.2 5.1 6.9 4 4 2 6 6 6 1 zinc-RING finger domain Pkinase PF00069.20 EPY51494.1 - 2.5e-74 249.7 0.0 3.2e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51494.1 - 2.1e-33 115.4 0.0 2.9e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51494.1 - 5.4e-06 25.5 0.0 1.9e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EPY51494.1 - 0.0016 18.2 0.2 0.35 10.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family ITI_HC_C PF06668.7 EPY51495.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus TGT PF01702.13 EPY51496.1 - 2.6e-32 111.9 0.0 1.9e-31 109.1 0.0 2.2 2 1 0 2 2 2 1 Queuine tRNA-ribosyltransferase Phosducin PF02114.11 EPY51496.1 - 0.00012 20.8 0.1 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EPY51496.1 - 0.00068 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DHHA2 PF02833.9 EPY51497.1 - 1.5e-19 70.4 0.3 3.4e-19 69.2 0.1 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.15 EPY51497.1 - 1.6e-12 47.3 0.0 4.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 DHH family Vps54 PF07928.7 EPY51498.1 - 7.5e-30 103.8 2.4 1.7e-29 102.6 0.7 2.5 2 0 0 2 2 2 1 Vps54-like protein DUF3980 PF13140.1 EPY51499.1 - 0.65 10.3 4.2 2.1 8.6 2.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3980) Aminotran_1_2 PF00155.16 EPY51500.1 - 7.6e-73 245.5 0.0 9.8e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPY51500.1 - 4.2e-06 25.7 0.0 9.6e-06 24.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPY51500.1 - 0.00061 18.1 0.0 0.0011 17.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.11 EPY51502.1 - 3.8e-22 78.5 26.5 3.8e-22 78.5 18.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily RAMP4 PF06624.7 EPY51502.1 - 0.5 9.9 3.3 0.95 9.0 0.0 2.5 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 MFS_2 PF13347.1 EPY51503.1 - 1.6e-10 39.9 14.3 1.6e-10 39.9 9.9 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein Reticulon PF02453.12 EPY51503.1 - 0.062 12.9 3.5 0.28 10.7 2.4 2.1 1 0 0 1 1 1 0 Reticulon DUF3246 PF11596.3 EPY51503.1 - 0.1 11.8 0.3 0.18 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Nucleoplasmin PF03066.10 EPY51503.1 - 0.23 10.9 1.6 0.42 10.1 1.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin TFIIF_alpha PF05793.7 EPY51503.1 - 0.66 8.2 2.3 0.91 7.8 1.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HEAT PF02985.17 EPY51504.1 - 1e-29 99.8 10.2 6e-05 22.7 0.0 10.8 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.1 EPY51504.1 - 1e-21 76.9 1.1 1.6e-05 25.0 0.0 7.3 3 3 5 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EPY51504.1 - 6.9e-21 74.1 5.3 1.1e-11 44.8 0.0 9.5 11 0 0 11 11 11 2 HEAT-like repeat Arm PF00514.18 EPY51504.1 - 4.6e-11 42.1 0.1 0.034 13.9 0.0 6.2 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EPY51504.1 - 9.2e-07 29.1 0.0 5.8 7.3 0.0 5.2 3 2 3 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EPY51504.1 - 1.5e-06 28.1 0.0 0.1 12.4 0.0 5.8 5 1 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EPY51504.1 - 4.7e-06 25.2 0.4 0.022 13.1 0.0 3.5 4 0 0 4 4 4 2 Adaptin N terminal region IBN_N PF03810.14 EPY51504.1 - 7.4e-06 25.7 0.4 0.0042 16.9 0.0 3.4 2 1 1 3 3 3 2 Importin-beta N-terminal domain CLASP_N PF12348.3 EPY51504.1 - 0.00086 18.7 0.0 2.6 7.3 0.0 4.8 3 2 1 4 4 4 1 CLASP N terminal MMS19_C PF12460.3 EPY51504.1 - 0.0035 16.1 0.1 2.3 6.8 0.0 3.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Ipi1_N PF12333.3 EPY51504.1 - 0.0048 16.8 0.2 3.2 7.7 0.0 4.2 5 0 0 5 5 3 1 Rix1 complex component involved in 60S ribosome maturation DUF2435 PF10363.4 EPY51504.1 - 0.0088 15.9 0.3 0.17 11.7 0.0 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) UNC45-central PF11701.3 EPY51504.1 - 0.025 14.2 0.0 0.084 12.5 0.0 1.9 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central Cohesin_HEAT PF12765.2 EPY51504.1 - 0.24 11.4 1.2 13 5.8 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF2457 PF10446.4 EPY51504.1 - 7.9 5.0 9.6 12 4.5 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aldo_ket_red PF00248.16 EPY51505.1 - 2e-47 161.3 0.0 2.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SSB PF00436.20 EPY51506.1 - 1.7e-12 47.1 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family RNA_pol_I_A49 PF06870.7 EPY51507.1 - 3.3e-101 338.6 0.8 4.6e-101 338.1 0.6 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor TPR_11 PF13414.1 EPY51508.1 - 6.9e-12 44.8 10.2 5.7e-09 35.4 0.9 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EPY51508.1 - 5e-08 32.2 7.6 0.035 13.7 0.5 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPY51508.1 - 1.4e-06 27.7 7.1 0.01 15.6 0.5 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPY51508.1 - 6.4e-06 26.0 2.6 0.0015 18.4 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY51508.1 - 0.0011 19.5 3.4 0.37 11.5 0.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPY51508.1 - 0.0012 18.0 0.3 0.0033 16.6 0.0 1.9 2 0 0 2 2 2 1 SHNi-TPR TPR_8 PF13181.1 EPY51508.1 - 0.018 14.7 5.1 8 6.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EPY51508.1 - 0.024 14.7 4.1 0.1 12.7 2.8 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPY51508.1 - 0.22 12.2 1.2 14 6.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPY51508.1 - 0.83 10.0 3.5 2.8 8.3 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LSM PF01423.17 EPY51509.1 - 3.8e-20 71.2 0.0 4.4e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPY51509.1 - 2.4e-05 24.1 0.0 2.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Gly_transf_sug PF04488.10 EPY51510.1 - 1.9e-22 79.6 0.2 3.6e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif zf-DHHC PF01529.15 EPY51510.1 - 0.11 11.9 3.6 0.44 9.9 1.2 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase TcdA_TcdB PF12919.2 EPY51510.1 - 0.18 10.2 4.3 0.65 8.4 0.2 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Sigma_reg_N PF13800.1 EPY51510.1 - 0.2 11.7 3.4 7.8 6.5 0.2 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4477 PF14780.1 EPY51511.1 - 0.0011 18.4 0.2 0.15 11.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) TSGP1 PF07771.6 EPY51511.1 - 0.59 10.0 3.2 1.1 9.1 2.2 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 MatE PF01554.13 EPY51512.1 - 1.1e-53 181.2 27.2 4.7e-29 101.1 4.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EPY51512.1 - 0.00045 20.0 7.4 0.00045 20.0 5.1 3.2 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain PHY PF00360.15 EPY51512.1 - 0.15 11.1 0.1 17 4.4 0.0 3.0 3 0 0 3 3 3 0 Phytochrome region ThiF PF00899.16 EPY51513.1 - 1.1e-08 35.0 0.0 2.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EPY51513.1 - 0.038 13.5 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 MoeZ/MoeB domain Methyltransf_26 PF13659.1 EPY51514.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY51514.1 - 8.9e-06 25.1 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EPY51514.1 - 0.03 14.8 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.22 EPY51515.1 - 1.3e-34 119.4 0.0 2e-16 60.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPY51515.1 - 1.6e-07 31.6 10.2 0.039 13.8 0.4 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPY51515.1 - 2.3e-06 27.0 0.4 0.0047 16.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EPY51515.1 - 1.4e-05 24.4 2.5 0.037 13.2 0.6 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPY51515.1 - 7.8e-05 22.8 0.0 0.25 11.4 0.0 3.0 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EPY51515.1 - 0.00036 20.4 0.0 0.28 11.1 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EPY51515.1 - 0.00088 18.9 0.3 2.9 7.5 0.0 3.6 3 1 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EPY51515.1 - 0.0034 18.1 0.1 0.78 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 EPY51515.1 - 0.0055 15.4 0.0 0.18 10.4 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.1 EPY51515.1 - 0.0085 16.4 3.7 0.67 10.2 0.3 2.5 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EPY51515.1 - 0.01 15.2 0.5 0.87 9.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EPY51515.1 - 0.012 15.0 0.1 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EPY51515.1 - 0.017 15.5 0.0 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EPY51515.1 - 0.022 14.7 0.1 9 6.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain UPF0079 PF02367.12 EPY51515.1 - 0.031 13.8 0.0 12 5.5 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 EPY51515.1 - 0.032 13.5 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_15 PF13175.1 EPY51515.1 - 0.035 13.1 0.0 14 4.5 0.0 3.3 3 1 0 4 4 4 0 AAA ATPase domain AAA_10 PF12846.2 EPY51515.1 - 0.043 13.2 2.2 2.5 7.4 0.1 2.9 2 1 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EPY51515.1 - 0.061 12.2 0.1 3.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Proteasome PF00227.21 EPY51517.1 - 1.6e-58 197.1 0.0 2.1e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPY51517.1 - 2.2e-14 52.4 0.0 3.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NAD_kinase PF01513.16 EPY51518.1 - 4.5e-51 173.3 0.0 5.8e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EPY51518.1 - 0.0049 16.2 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Acyl_transf_1 PF00698.16 EPY51519.1 - 4.4e-72 243.0 0.1 1e-69 235.3 0.0 3.3 3 1 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EPY51519.1 - 8.5e-31 105.9 1.4 6.7e-30 102.9 0.1 2.5 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EPY51519.1 - 1e-28 98.8 0.0 2.8e-28 97.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EPY51519.1 - 1.4e-19 70.1 1.2 4.8e-19 68.4 0.1 2.5 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase PBP_GOBP PF01395.17 EPY51519.1 - 0.46 10.1 0.1 0.86 9.2 0.1 1.3 1 0 0 1 1 1 0 PBP/GOBP family Brix PF04427.13 EPY51520.1 - 3.1e-36 124.8 0.0 4.2e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Dynein_light PF01221.13 EPY51521.1 - 2.4e-40 136.3 1.6 3.7e-40 135.8 1.1 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3306 PF11748.3 EPY51521.1 - 0.096 13.3 1.4 0.13 12.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF2275 PF10039.4 EPY51521.1 - 0.097 12.5 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) LRR_8 PF13855.1 EPY51522.1 - 1.8e-14 53.1 11.8 1.5e-10 40.6 3.6 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EPY51522.1 - 3.2e-14 52.1 18.1 5.6e-09 35.4 1.3 5.0 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPY51522.1 - 2.5e-06 26.7 20.6 0.015 15.2 0.1 7.7 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 EPY51522.1 - 0.00013 21.5 21.7 0.42 11.0 0.1 7.3 7 0 0 7 7 7 2 Leucine rich repeat DASH_Dad1 PF08649.5 EPY51522.1 - 0.011 15.4 0.1 0.034 13.8 0.1 1.9 1 0 0 1 1 1 0 DASH complex subunit Dad1 UBN2 PF14223.1 EPY51522.1 - 0.042 13.6 0.2 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type LRR_6 PF13516.1 EPY51522.1 - 0.053 13.6 17.5 2.2 8.6 0.1 5.5 5 1 1 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.1 EPY51522.1 - 0.17 11.4 0.5 0.55 9.7 0.3 1.8 1 0 0 1 1 1 0 Leucine-rich repeat zf-CSL PF05207.8 EPY51523.1 - 5.8e-17 60.9 0.8 1.1e-16 60.0 0.5 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EPY51523.1 - 4.2e-11 42.4 0.5 1.2e-10 40.9 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain DCAF15_WD40 PF14939.1 EPY51523.1 - 0.033 13.5 0.1 0.082 12.2 0.1 1.6 1 1 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat P-mevalo_kinase PF04275.9 EPY51523.1 - 0.06 13.0 0.3 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 Phosphomevalonate kinase HSP90 PF00183.13 EPY51524.1 - 4.2e-258 857.0 28.8 5.1e-258 856.8 19.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EPY51524.1 - 1.4e-11 44.0 0.0 2.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPY51524.1 - 6.7e-11 41.9 0.1 6.7e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_6 PF13405.1 EPY51525.1 - 2.4e-11 42.5 1.3 3.7e-06 26.3 0.2 3.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EPY51525.1 - 3.7e-11 41.4 1.8 7.3e-08 31.1 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EPY51525.1 - 3.6e-10 39.8 0.8 6.7e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPY51525.1 - 3.1e-05 23.1 3.0 0.00078 18.6 0.8 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EPY51525.1 - 0.0022 17.5 2.6 0.0062 16.1 0.2 2.9 3 1 1 4 4 4 1 EF-hand domain pair UPF0154 PF03672.8 EPY51525.1 - 0.12 12.0 0.1 1.1 8.9 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF999 PF06198.6 EPY51526.1 - 1.6e-06 27.9 2.2 4.6e-06 26.4 1.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF999) HemY_N PF07219.8 EPY51526.1 - 0.41 10.2 1.4 2 7.9 0.4 2.1 2 0 0 2 2 2 0 HemY protein N-terminus DUF2207 PF09972.4 EPY51526.1 - 1.4 7.4 6.6 2.5 6.5 4.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) AF2331-like PF14556.1 EPY51527.1 - 0.042 14.1 1.2 0.1 12.9 0.2 1.8 1 1 1 2 2 2 0 AF2331-like TPR_11 PF13414.1 EPY51528.1 - 3.1e-06 26.7 14.1 0.0023 17.5 0.5 4.5 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EPY51528.1 - 9.2e-05 22.3 6.9 0.016 15.3 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY51528.1 - 0.00019 22.0 4.1 0.011 16.3 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Mgr1 PF08602.5 EPY51528.1 - 0.026 13.5 0.9 0.045 12.7 0.2 1.6 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit TPR_14 PF13428.1 EPY51528.1 - 0.16 12.7 5.7 0.84 10.4 0.0 4.2 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPY51528.1 - 0.35 10.8 7.7 2.9 7.8 0.9 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Flavin_Reduct PF01613.13 EPY51529.1 - 2.7e-34 118.2 1.9 2.7e-34 118.2 1.3 1.5 2 0 0 2 2 2 1 Flavin reductase like domain LMWPc PF01451.16 EPY51530.1 - 3.1e-40 137.6 0.0 3.5e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase E1-E2_ATPase PF00122.15 EPY51531.1 - 1.6e-58 197.4 4.6 1.6e-58 197.4 3.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPY51531.1 - 3.3e-24 86.5 0.0 6.5e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPY51531.1 - 2.4e-12 47.4 0.0 5.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPY51531.1 - 4.8e-11 41.9 0.0 1.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPY51531.1 - 0.0017 17.9 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY51531.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF843 PF05814.6 EPY51531.1 - 2.7 7.8 0.0 2.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) DnaJ PF00226.26 EPY51532.1 - 6.2e-20 70.7 2.5 6.2e-20 70.7 1.7 2.3 3 0 0 3 3 3 1 DnaJ domain RHD PF00554.17 EPY51532.1 - 0.15 11.7 0.2 0.15 11.7 0.1 2.3 2 1 0 2 2 2 0 Rel homology domain (RHD) Ribosomal_60s PF00428.14 EPY51533.1 - 1.5e-28 99.0 13.9 1.7e-28 98.8 9.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3245 PF11595.3 EPY51533.1 - 0.031 14.5 0.2 0.038 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF867 PF05908.6 EPY51533.1 - 0.071 12.1 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF867) Condensin2nSMC PF12422.3 EPY51533.1 - 0.095 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DUF3138 PF11336.3 EPY51533.1 - 0.18 9.9 0.9 0.17 10.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_S19 PF00203.16 EPY51534.1 - 1.3e-30 104.8 0.1 1.8e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EPY51534.1 - 0.056 13.4 0.6 9.2 6.3 0.6 2.1 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Actin PF00022.14 EPY51535.1 - 2.1e-38 131.7 0.0 1.1e-37 129.3 0.0 2.0 1 1 0 1 1 1 1 Actin Methyltransf_16 PF10294.4 EPY51536.1 - 0.069 12.5 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase SPC25 PF06703.6 EPY51537.1 - 1.9e-28 99.0 0.1 2.1e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Glyco_transf_15 PF01793.11 EPY51537.1 - 0.072 12.0 1.9 0.1 11.5 1.4 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase MMS19_C PF12460.3 EPY51539.1 - 2.4e-80 270.3 16.7 2.4e-80 270.3 11.6 2.2 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EPY51539.1 - 2.2e-74 250.0 0.3 2.2e-74 250.0 0.2 3.5 4 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 EPY51539.1 - 0.0023 18.3 2.9 0.5 10.9 0.2 5.5 3 1 2 5 5 5 2 HEAT-like repeat Ion_trans_N PF08412.5 EPY51539.1 - 0.0024 17.1 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Ion transport protein N-terminal DUF3453 PF11935.3 EPY51540.1 - 3.1e-53 180.6 0.6 3.1e-53 180.6 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Neogenin_C PF06583.7 EPY51540.1 - 0.065 12.8 0.1 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Neogenin C-terminus TSC22 PF01166.13 EPY51541.1 - 0.0013 18.6 2.5 0.0013 18.6 1.7 4.8 5 1 0 5 5 5 2 TSC-22/dip/bun family Cep57_MT_bd PF06657.8 EPY51541.1 - 0.039 13.8 29.4 0.22 11.4 2.7 5.4 5 1 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 WEMBL PF05701.6 EPY51541.1 - 0.55 8.6 40.2 1.9 6.8 15.2 3.0 2 1 1 3 3 3 0 Weak chloroplast movement under blue light DASH_Dam1 PF08653.5 EPY51541.1 - 3.5 7.4 11.4 8.9 6.1 0.2 4.4 3 1 1 4 4 4 0 DASH complex subunit Dam1 Reo_sigmaC PF04582.7 EPY51541.1 - 4.6 6.3 19.6 1.1 8.3 3.9 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Rootletin PF15035.1 EPY51541.1 - 6.6 6.6 34.4 1.3 9.0 12.3 3.4 3 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Pcc1 PF09341.5 EPY51542.1 - 5.2e-21 74.4 0.0 5.8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Cep57_MT_bd PF06657.8 EPY51543.1 - 1.7e-20 72.7 1.7 1.7e-20 72.7 1.2 4.3 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EPY51543.1 - 2.1e-05 24.3 7.8 2.1e-05 24.3 5.4 3.6 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 APG17 PF04108.7 EPY51543.1 - 0.00036 19.4 0.1 0.00036 19.4 0.0 3.0 2 1 1 3 3 3 1 Autophagy protein Apg17 Mac PF12464.3 EPY51543.1 - 0.3 11.1 5.2 1.4 8.9 0.3 3.0 2 1 0 2 2 2 0 Maltose acetyltransferase bZIP_1 PF00170.16 EPY51543.1 - 0.85 9.6 24.4 1.3 9.0 0.4 5.5 5 0 0 5 5 5 0 bZIP transcription factor DUF4407 PF14362.1 EPY51543.1 - 5.8 5.7 6.1 16 4.2 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PK PF00224.16 EPY51544.1 - 2.8e-165 549.1 3.1 3.6e-165 548.7 2.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EPY51544.1 - 2.1e-27 94.9 0.1 7.9e-27 93.1 0.1 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EPY51544.1 - 3.1e-06 26.2 0.4 7.4e-06 25.0 0.3 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family POC1 PF10450.4 EPY51544.1 - 0.078 11.7 0.2 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 POC1 chaperone PP-binding PF00550.20 EPY51545.1 - 2.5e-13 50.0 0.1 3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EPY51545.1 - 6e-05 22.9 0.4 9e-05 22.4 0.3 1.3 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EPY51545.1 - 0.0051 16.8 0.1 0.0066 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Glyco_hydro_81 PF03639.8 EPY51546.1 - 4.3e-241 801.7 15.3 4.9e-241 801.5 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Rhodanese PF00581.15 EPY51547.1 - 6.3e-19 68.3 0.0 8.5e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF442 PF04273.8 EPY51547.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Putative phosphatase (DUF442) HSF_DNA-bind PF00447.12 EPY51547.1 - 0.13 12.4 0.0 1.4 9.0 0.0 2.0 2 0 0 2 2 2 0 HSF-type DNA-binding DNA_repr_REX1B PF14966.1 EPY51548.1 - 9.5e-10 38.7 1.6 9.5e-10 38.7 1.1 1.7 1 1 1 2 2 2 1 DNA repair REX1-B GIDA PF01134.17 EPY51548.1 - 0.0052 15.7 0.7 0.0059 15.5 0.5 1.2 1 1 0 1 1 1 1 Glucose inhibited division protein A DUF2779 PF11074.3 EPY51548.1 - 0.036 14.1 0.4 0.05 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) DUF3391 PF11871.3 EPY51548.1 - 0.042 14.0 0.7 0.063 13.4 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) SBF2 PF12335.3 EPY51548.1 - 0.053 12.8 0.4 0.087 12.1 0.1 1.5 1 1 1 2 2 2 0 Myotubularin protein Baculo_PEP_C PF04513.7 EPY51548.1 - 0.093 12.5 4.3 0.14 11.9 3.0 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2746 PF10874.3 EPY51548.1 - 0.19 11.9 1.7 0.67 10.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2746) Syntaxin PF00804.20 EPY51548.1 - 0.22 11.7 12.7 1.1 9.4 4.8 2.8 1 1 1 2 2 2 0 Syntaxin Seryl_tRNA_N PF02403.17 EPY51548.1 - 0.7 9.9 8.2 0.81 9.7 1.3 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.4 EPY51548.1 - 1.2 9.4 5.2 4.5 7.5 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF641 PF04859.7 EPY51548.1 - 1.8 8.3 5.9 0.5 10.1 1.0 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Rho_Binding PF08912.6 EPY51548.1 - 2.5 8.4 6.8 1.1 9.6 0.7 2.4 2 1 0 2 2 2 0 Rho Binding TBPIP PF07106.8 EPY51548.1 - 3.1 7.3 10.6 5 6.6 5.4 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Btz PF09405.5 EPY51549.1 - 0.0049 16.9 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding zf-B_box PF00643.19 EPY51549.1 - 6.4 6.7 15.9 1.5 8.7 7.2 2.3 2 0 0 2 2 2 0 B-box zinc finger UvrD_C PF13361.1 EPY51550.1 - 2.7e-79 267.2 2.0 2.7e-79 267.2 1.4 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EPY51550.1 - 7.8e-66 222.5 0.2 7.8e-66 222.5 0.1 3.1 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EPY51550.1 - 1.1e-12 48.0 0.0 7.5e-12 45.3 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EPY51550.1 - 1.6e-11 43.7 0.1 7e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EPY51550.1 - 4.2e-07 29.7 1.5 0.013 15.0 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EPY51550.1 - 2e-05 24.0 0.1 0.0007 19.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EPY51550.1 - 0.00023 20.8 0.0 0.0058 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Memo PF01875.12 EPY51551.1 - 1.6e-91 306.0 0.0 1.8e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein PRTase_3 PF15610.1 EPY51551.1 - 0.03 13.2 0.1 1 8.2 0.0 2.2 2 0 0 2 2 2 0 PRTase ComF-like Glyco_hydro_15 PF00723.16 EPY51552.1 - 1.8e-72 244.3 0.0 9.1e-72 242.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF1147 PF06615.6 EPY51552.1 - 0.067 13.0 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) DnaJ-X PF14308.1 EPY51554.1 - 1.4e-55 187.7 0.8 1.4e-55 187.7 0.5 2.2 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EPY51554.1 - 4.7e-27 93.5 0.6 1.8e-26 91.6 0.4 2.1 1 0 0 1 1 1 1 DnaJ domain Peptidase_S46 PF10459.4 EPY51554.1 - 0.00087 17.8 9.7 0.0013 17.2 6.7 1.2 1 0 0 1 1 1 1 Peptidase S46 NAAA-beta PF15508.1 EPY51554.1 - 0.086 13.1 0.4 11 6.4 0.1 2.8 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase KilA-N PF04383.8 EPY51554.1 - 0.1 12.2 1.0 0.23 11.0 0.2 1.9 1 1 1 2 2 2 0 KilA-N domain AKNA PF12443.3 EPY51554.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.9 2 0 0 2 2 2 0 AT-hook-containing transcription factor PRTP PF01366.13 EPY51554.1 - 0.51 8.2 6.9 0.92 7.4 4.8 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Cyt-b5 PF00173.23 EPY51555.1 - 1.8e-20 72.4 0.0 2.5e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PIG-S PF10510.4 EPY51556.1 - 2.2e-101 340.1 8.1 1.6e-99 333.9 5.6 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein HEPN PF05168.9 EPY51556.1 - 0.0062 16.4 0.2 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 HEPN domain CTP_transf_2 PF01467.21 EPY51557.1 - 0.0064 16.5 0.2 0.022 14.8 0.1 2.0 1 1 0 1 1 1 1 Cytidylyltransferase Aminotran_5 PF00266.14 EPY51558.1 - 9.3e-35 120.0 0.0 1.1e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Endonuclease_5 PF04493.9 EPY51559.1 - 1.1e-60 204.4 0.0 1.4e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 EPY51559.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 RE_NgoBV PF09564.5 EPY51559.1 - 0.11 11.7 0.0 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 NgoBV restriction endonuclease LDB19 PF13002.2 EPY51560.1 - 1.2e-37 129.2 0.8 1.8e-37 128.6 0.6 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EPY51560.1 - 3e-08 33.6 0.3 1.1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PEX11 PF05648.9 EPY51561.1 - 3.5e-05 23.1 2.4 0.0085 15.3 0.0 2.6 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) TCTP PF00838.12 EPY51562.1 - 5.2e-73 244.4 1.8 5.9e-73 244.2 1.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Spermine_synth PF01564.12 EPY51562.1 - 0.088 11.7 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase CBS PF00571.23 EPY51563.1 - 1.1e-24 85.9 2.2 1.9e-09 37.1 0.0 4.3 4 0 0 4 4 4 4 CBS domain PMM PF03332.8 EPY51564.1 - 8.6e-113 375.3 1.1 9.9e-113 375.1 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EPY51564.1 - 1.8e-05 24.4 0.0 7.3e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPY51564.1 - 0.038 14.1 0.0 0.066 13.3 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EPY51564.1 - 0.045 12.8 0.1 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4266 PF14086.1 EPY51565.1 - 0.052 14.0 0.0 0.21 12.0 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) SpoIIE PF07228.7 EPY51566.1 - 8.4e-12 45.1 0.0 1.1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EPY51566.1 - 1.2e-08 34.6 0.0 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EPY51566.1 - 7.6e-08 32.0 0.0 4.8e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Cgr1 PF03879.9 EPY51567.1 - 2.5e-32 111.2 29.0 3e-32 111.0 20.1 1.0 1 0 0 1 1 1 1 Cgr1 family CRISPR_Cas2 PF09827.4 EPY51567.1 - 3.2 7.9 7.0 0.28 11.3 1.0 2.0 1 1 0 2 2 2 0 CRISPR associated protein Cas2 Vfa1 PF08432.5 EPY51567.1 - 6.9 6.6 15.1 7.9 6.4 10.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 dCMP_cyt_deam_1 PF00383.17 EPY51568.1 - 4.2e-16 58.4 0.0 5e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EPY51568.1 - 2.1e-07 30.9 0.1 4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EPY51568.1 - 0.00092 18.6 0.5 0.042 13.2 0.1 2.0 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases FAD_binding_2 PF00890.19 EPY51569.1 - 5.1e-125 417.5 1.8 6.6e-125 417.2 1.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EPY51569.1 - 5.9e-46 155.5 0.4 8.6e-46 154.9 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EPY51569.1 - 1.7e-05 24.8 0.0 0.025 14.4 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPY51569.1 - 5.2e-05 22.4 0.3 0.085 11.9 0.0 3.3 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EPY51569.1 - 5.6e-05 22.1 0.6 0.055 12.3 1.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EPY51569.1 - 0.00048 19.1 0.2 0.011 14.6 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPY51569.1 - 0.019 14.0 0.2 0.034 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EPY51569.1 - 0.51 8.7 2.1 1.5 7.1 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein AAA_23 PF13476.1 EPY51570.1 - 5.3e-25 88.9 1.1 5.3e-25 88.9 0.8 7.1 2 2 3 5 5 5 1 AAA domain SMC_N PF02463.14 EPY51570.1 - 2.2e-12 46.6 6.9 8.3e-07 28.4 2.9 4.1 5 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.9 EPY51570.1 - 9.7e-11 40.9 0.1 9.7e-11 40.9 0.1 6.4 8 0 0 8 8 8 1 Rad50 zinc hook motif SbcCD_C PF13558.1 EPY51570.1 - 4.1e-10 39.4 0.0 1.3e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EPY51570.1 - 1.2e-07 30.6 133.5 0.00011 20.8 0.0 8.2 3 1 6 9 9 9 5 AAA domain Reo_sigmaC PF04582.7 EPY51570.1 - 0.00022 20.5 41.0 0.14 11.2 1.5 6.3 5 2 2 7 7 7 5 Reovirus sigma C capsid protein AAA_21 PF13304.1 EPY51570.1 - 0.00054 20.0 0.0 0.00054 20.0 0.0 6.0 3 2 2 5 5 5 2 AAA domain AAA_29 PF13555.1 EPY51570.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EPY51570.1 - 0.012 15.6 0.1 0.012 15.6 0.1 4.6 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.22 EPY51570.1 - 0.029 14.6 0.1 0.029 14.6 0.0 6.5 3 2 1 4 4 4 0 ABC transporter MMgT PF10270.4 EPY51571.1 - 0.00014 22.2 0.4 0.00021 21.6 0.3 1.3 1 1 0 1 1 1 1 Membrane magnesium transporter HSP20 PF00011.16 EPY51572.1 - 8.9e-23 80.1 0.5 1.1e-22 79.8 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY51572.1 - 0.0016 18.9 0.6 0.2 12.2 0.0 2.2 2 0 0 2 2 2 2 CS domain PIH1 PF08190.7 EPY51572.1 - 0.041 13.3 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 adh_short PF00106.20 EPY51573.1 - 2.4e-34 118.6 0.1 3e-34 118.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY51573.1 - 4.9e-29 101.7 0.0 6.1e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY51573.1 - 1.1e-14 54.4 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPY51573.1 - 0.00017 20.8 0.0 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EPY51573.1 - 0.0012 18.9 0.4 0.0021 18.1 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY51573.1 - 0.0066 15.9 0.2 0.011 15.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPY51573.1 - 0.02 14.6 0.1 0.056 13.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPY51573.1 - 0.05 12.6 0.2 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MUG2_C PF08593.5 EPY51574.1 - 1.2e-14 54.2 0.0 2.9e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal DUF4030 PF13222.1 EPY51574.1 - 0.013 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) P22_CoatProtein PF11651.3 EPY51574.1 - 0.11 11.0 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 DnaA_N PF11638.3 EPY51575.1 - 0.00084 18.8 4.4 0.09 12.3 0.2 3.4 2 1 1 3 3 3 2 DnaA N-terminal domain adh_short PF00106.20 EPY51576.1 - 1.8e-34 119.0 0.1 2.2e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY51576.1 - 1.2e-29 103.7 0.0 1.6e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY51576.1 - 6.2e-15 55.3 0.0 8.3e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY51576.1 - 0.00025 21.0 0.6 0.00048 20.1 0.4 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EPY51576.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EPY51576.1 - 0.004 16.6 0.4 0.0079 15.6 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPY51576.1 - 0.018 14.8 0.1 0.054 13.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPY51576.1 - 0.065 12.3 0.1 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EPY51576.1 - 0.16 11.6 0.9 0.24 11.0 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EPY51577.1 - 2.8e-33 115.1 0.1 3.5e-33 114.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY51577.1 - 3.2e-32 112.2 0.0 3.9e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY51577.1 - 6.2e-13 48.7 0.0 8.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY51577.1 - 0.0009 19.2 1.0 0.0018 18.3 0.7 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY51577.1 - 0.0093 15.4 0.4 0.028 13.8 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPY51577.1 - 0.0093 15.0 0.2 0.032 13.2 0.0 1.9 1 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EPY51577.1 - 0.023 14.4 0.3 0.069 12.9 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EPY51577.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) AP_endonuc_2 PF01261.19 EPY51578.1 - 1.7e-36 125.5 0.0 4.9e-36 124.0 0.0 1.6 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.7 EPY51578.1 - 0.021 14.3 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus FAD-oxidase_C PF02913.14 EPY51578.1 - 0.058 12.7 0.0 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain Con-6 PF10346.4 EPY51579.1 - 1.9e-30 103.9 9.2 2e-15 55.8 1.4 2.2 2 0 0 2 2 2 2 Conidiation protein 6 DUF1752 PF08550.5 EPY51579.1 - 0.068 12.7 0.5 0.14 11.7 0.4 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Takusan PF04822.8 EPY51579.1 - 0.19 11.5 2.8 2.3 8.0 0.2 2.1 2 0 0 2 2 2 0 Takusan Toxin_43 PF15604.1 EPY51579.1 - 0.19 11.7 6.4 1.5 8.8 3.7 2.0 1 1 1 2 2 2 0 Putative toxin 43 MEF2_binding PF09047.5 EPY51579.1 - 0.39 10.3 1.9 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 MEF2 binding Catalase PF00199.14 EPY51580.1 - 1.4e-160 534.2 1.6 8.7e-84 281.4 0.1 2.1 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.7 EPY51580.1 - 9.4e-15 54.2 0.5 4.9e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive COX14 PF14880.1 EPY51581.1 - 6e-06 25.7 0.0 7.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly FtsL PF04999.8 EPY51581.1 - 0.032 13.9 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 Cell division protein FtsL IBD PF10416.4 EPY51581.1 - 0.096 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD RNase_PH PF01138.16 EPY51582.1 - 1.7e-20 73.6 0.4 3.9e-20 72.5 0.0 1.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPY51582.1 - 2.3e-10 40.2 0.0 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 KH_1 PF00013.24 EPY51583.1 - 2.2e-39 132.9 3.1 3.6e-16 58.5 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPY51583.1 - 1.1e-29 101.4 9.6 6.4e-12 44.8 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPY51583.1 - 7.9e-12 44.5 1.9 0.0047 16.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPY51583.1 - 3e-07 29.9 0.6 0.11 12.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EPY51583.1 - 0.00026 20.7 2.0 0.13 12.0 0.1 3.2 3 0 0 3 3 3 2 NusA-like KH domain MFS_1 PF07690.11 EPY51584.1 - 3.4e-45 154.2 26.8 7.3e-45 153.2 17.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3796 PF12676.2 EPY51584.1 - 0.21 11.8 0.1 0.21 11.8 0.1 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3796) DUF202 PF02656.10 EPY51584.1 - 3.8 7.8 8.3 3 8.1 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Alpha-amylase PF00128.19 EPY51585.1 - 1.1e-55 189.2 2.8 2.3e-55 188.2 1.9 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPY51585.1 - 7.2e-18 64.4 0.3 7.2e-18 64.4 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) SPRY PF00622.23 EPY51585.1 - 0.025 14.6 0.3 14 5.7 0.0 3.0 2 1 0 2 2 2 0 SPRY domain TMEM52 PF14979.1 EPY51586.1 - 0.068 13.0 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Transmembrane 52 Vma12 PF11712.3 EPY51587.1 - 3.2e-15 56.0 0.0 4.4e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ETRAMP PF09716.5 EPY51587.1 - 6.4 6.8 6.3 1.7 8.6 1.1 2.5 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Catalase PF00199.14 EPY51588.1 - 2.3e-175 582.8 0.3 2.7e-175 582.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPY51588.1 - 1.1e-14 53.9 0.1 2.9e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.11 EPY51589.1 - 6.7e-24 84.2 24.1 6.7e-24 84.2 16.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0542 PF15086.1 EPY51589.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 UPF0370 PF13980.1 EPY51589.1 - 0.34 10.7 5.7 2.8 7.8 0.0 3.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) Redoxin PF08534.5 EPY51591.1 - 1.8e-29 102.1 0.1 2e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPY51591.1 - 5e-11 42.3 0.0 6.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family SAP PF02037.22 EPY51592.1 - 0.0044 16.4 0.1 0.008 15.6 0.0 1.5 1 1 0 1 1 1 1 SAP domain OMPdecase PF00215.19 EPY51593.1 - 3.6e-79 265.3 0.0 4.1e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family RAMP4 PF06624.7 EPY51594.1 - 0.0014 18.1 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Glycos_transf_1 PF00534.15 EPY51595.1 - 5.4e-19 68.2 0.0 7.4e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPY51595.1 - 4.8e-09 36.4 0.0 1.3e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPY51595.1 - 5.3e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 FBD PF08387.5 EPY51595.1 - 0.11 11.9 0.1 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 FBD Ribosomal_L6 PF00347.18 EPY51596.1 - 1.9e-32 111.6 4.8 9.3e-18 64.5 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L29 PF00831.18 EPY51597.1 - 2.4e-20 71.9 3.7 2.4e-20 71.9 2.6 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EPY51597.1 - 0.026 14.7 2.4 0.074 13.3 1.7 1.7 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Annexin PF00191.15 EPY51597.1 - 0.036 13.9 1.1 0.042 13.7 0.1 1.7 2 0 0 2 2 2 0 Annexin DUF1013 PF06242.6 EPY51597.1 - 0.06 13.3 3.1 0.12 12.3 1.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Snapin_Pallidin PF14712.1 EPY51597.1 - 0.11 12.7 4.0 0.063 13.5 1.2 1.7 1 1 0 1 1 1 0 Snapin/Pallidin GAS PF13851.1 EPY51597.1 - 0.12 11.5 10.6 0.046 12.9 1.8 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SRP_SPB PF02978.14 EPY51597.1 - 0.15 12.3 1.1 2 8.7 0.1 2.2 1 1 1 2 2 2 0 Signal peptide binding domain PGC7_Stella PF15549.1 EPY51597.1 - 0.51 10.3 4.7 0.66 9.9 3.2 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Prefoldin PF02996.12 EPY51597.1 - 0.61 9.7 6.4 3.2 7.4 0.0 2.6 3 0 0 3 3 3 0 Prefoldin subunit UNC45-central PF11701.3 EPY51598.1 - 4.9e-05 23.0 11.3 0.00022 20.9 0.4 4.0 4 1 1 5 5 5 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EPY51598.1 - 0.0094 16.2 0.2 0.15 12.3 0.0 3.2 3 1 0 3 3 3 1 HEAT repeats DUF4368 PF14287.1 EPY51598.1 - 0.012 15.3 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) V-ATPase_H_C PF11698.3 EPY51598.1 - 0.014 15.3 0.8 0.75 9.7 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit H HEAT PF02985.17 EPY51598.1 - 0.098 12.7 1.3 21 5.5 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.18 EPY51598.1 - 0.17 11.7 10.5 5 7.0 0.0 5.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat EF-hand_7 PF13499.1 EPY51599.1 - 0.0042 17.1 1.1 0.013 15.6 0.8 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPY51599.1 - 0.019 14.8 1.6 0.51 10.3 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain CDC45 PF02724.9 EPY51600.1 - 0.038 12.0 13.3 0.004 15.2 5.4 1.8 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 EPY51600.1 - 0.16 9.8 14.9 0.013 13.4 7.3 1.5 2 0 0 2 2 2 0 Nop14-like family Afi1 PF07792.7 EPY51600.1 - 2.1 8.3 7.9 1 9.3 3.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SMN PF06003.7 EPY51600.1 - 7.2 5.6 17.5 1.3 8.0 0.8 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) BCIP PF13862.1 EPY51601.1 - 1.9e-72 242.8 0.3 2.4e-72 242.5 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PepX_N PF09168.5 EPY51601.1 - 0.053 13.7 0.0 2 8.6 0.1 2.5 1 1 1 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal MBD PF01429.14 EPY51601.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyl-CpG binding domain tRNA_int_end_N2 PF12928.2 EPY51602.1 - 2.6e-28 97.2 0.1 4.7e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EPY51602.1 - 0.0085 15.6 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Peptidase_M16 PF00675.15 EPY51603.1 - 2.1e-20 73.0 0.0 4.7e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPY51603.1 - 2.1e-12 47.0 0.0 1.7e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain WD40 PF00400.27 EPY51604.1 - 1.3e-21 75.6 5.5 9e-08 31.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat SNF2_N PF00176.18 EPY51605.1 - 7.3e-68 228.5 0.0 1.1e-67 227.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY51605.1 - 8e-12 44.8 0.0 1.9e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EPY51605.1 - 2.6e-07 30.1 7.5 2.6e-07 30.1 5.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPY51605.1 - 9.6e-05 22.1 6.3 9.6e-05 22.1 4.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EPY51605.1 - 0.00012 21.9 7.0 0.00012 21.9 4.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY51605.1 - 0.00036 20.3 7.1 0.00036 20.3 4.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY51605.1 - 0.0006 19.4 5.9 0.0006 19.4 4.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EPY51605.1 - 0.00084 18.8 0.0 0.0022 17.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 EPY51605.1 - 0.0066 16.1 2.6 0.019 14.6 1.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EPY51605.1 - 0.3 10.8 3.6 0.79 9.5 2.5 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EPY51606.1 - 0.0064 15.9 0.6 0.015 14.8 0.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger LRR_6 PF13516.1 EPY51606.1 - 0.0097 15.8 22.1 20 5.6 0.1 9.2 9 2 1 10 10 10 1 Leucine Rich repeat LRR_2 PF07723.8 EPY51606.1 - 0.012 16.0 0.9 0.012 16.0 0.6 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 EPY51606.1 - 0.042 13.4 13.2 22 4.7 0.0 6.7 4 3 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2477 PF10631.4 EPY51606.1 - 0.071 13.3 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Tubulin PF00091.20 EPY51607.1 - 7.8e-74 248.1 0.0 1.3e-73 247.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPY51607.1 - 9.6e-46 154.9 0.8 1.7e-45 154.1 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPY51607.1 - 1.9e-06 27.9 0.0 4.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Transposase_mut PF00872.13 EPY51607.1 - 0.13 10.8 0.1 6.4 5.2 0.0 2.2 2 0 0 2 2 2 0 Transposase, Mutator family Isy1 PF06246.7 EPY51608.1 - 8.5e-53 179.3 9.9 2.2e-51 174.7 6.8 2.0 1 1 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EPY51608.1 - 0.046 13.5 2.1 0.094 12.5 0.2 2.1 2 0 0 2 2 2 0 YolD-like protein Cyclin_N PF00134.18 EPY51609.1 - 7.3e-17 61.1 0.2 1.3e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPY51609.1 - 0.00083 19.2 0.7 0.1 12.5 0.0 2.8 2 1 1 3 3 3 2 Cyclin, C-terminal domain TFIIB PF00382.14 EPY51609.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat RINGv PF12906.2 EPY51610.1 - 1.3e-07 31.5 7.8 4.2e-07 29.8 4.7 2.5 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EPY51610.1 - 9.7e-05 22.1 6.8 9.7e-05 22.1 4.7 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING-like PF08746.6 EPY51610.1 - 0.011 15.7 4.6 0.042 13.8 3.2 2.0 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EPY51610.1 - 0.045 13.3 6.8 0.15 11.7 4.7 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EPY51610.1 - 1.4 9.0 14.1 0.067 13.2 3.4 3.2 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY51610.1 - 8.1 6.1 10.3 2.4 7.8 4.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DASH_Duo1 PF08651.5 EPY51611.1 - 2.7e-21 74.9 4.7 5.3e-21 73.9 3.3 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 PGM_PMM_I PF02878.11 EPY51613.1 - 2.8e-36 124.0 0.1 5.8e-36 123.0 0.1 1.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EPY51613.1 - 6.7e-21 74.4 0.0 1.2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EPY51613.1 - 1.9e-15 57.0 0.0 8.6e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EPY51613.1 - 1.4e-09 37.8 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Gp_dh_C PF02800.15 EPY51614.1 - 2.7e-72 241.3 0.1 4.2e-72 240.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPY51614.1 - 4.7e-60 201.9 0.2 7.7e-60 201.2 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EPY51614.1 - 0.014 15.3 0.3 0.058 13.3 0.0 2.1 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus OstA PF03968.9 EPY51614.1 - 0.035 14.0 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 OstA-like protein ADH_zinc_N PF00107.21 EPY51614.1 - 0.088 12.3 0.2 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPY51614.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tbf5 PF06331.7 EPY51615.1 - 3.8e-26 90.6 0.4 4.1e-26 90.5 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Cg6151-P PF10233.4 EPY51616.1 - 3.6e-34 117.1 14.0 4.4e-34 116.8 9.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.8 EPY51616.1 - 0.33 10.5 10.5 6.6 6.3 7.3 2.5 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Mago-bind PF09282.5 EPY51617.1 - 1.4e-10 40.5 0.3 3.1e-10 39.4 0.2 1.6 1 0 0 1 1 1 1 Mago binding zf-UBR PF02207.15 EPY51618.1 - 5.2e-18 64.5 10.8 5.2e-18 64.5 7.5 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EPY51618.1 - 0.00021 20.9 0.0 0.00071 19.2 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Zwint PF15556.1 EPY51618.1 - 0.0054 16.0 0.9 0.0096 15.2 0.6 1.3 1 0 0 1 1 1 1 ZW10 interactor RNA_pol_Rbc25 PF08292.7 EPY51619.1 - 3.5e-39 133.7 0.0 5.2e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EPY51619.1 - 3.5e-17 62.2 0.0 5e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPY51619.1 - 0.0058 16.7 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 S1 RNA binding domain Pyr_redox_2 PF07992.9 EPY51620.1 - 7.1e-10 39.0 0.0 5.3e-09 36.2 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPY51620.1 - 0.0055 15.6 0.0 0.92 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EPY51620.1 - 0.014 14.2 0.0 0.56 9.0 0.1 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EPY51620.1 - 0.065 13.0 0.0 15 5.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EPY51620.1 - 0.14 10.9 0.0 0.37 9.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain CENP-F_N PF10481.4 EPY51620.1 - 0.23 10.7 0.0 0.34 10.2 0.0 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain Transketolase_N PF00456.16 EPY51621.1 - 6.6e-139 462.3 0.0 8.6e-139 461.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EPY51621.1 - 3.3e-46 156.9 0.0 6.7e-46 156.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPY51621.1 - 6.5e-11 42.2 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EPY51621.1 - 1.3e-06 28.0 0.0 6.7e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EPY51621.1 - 2.2e-06 26.6 0.0 4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EPY51621.1 - 0.00057 18.8 0.0 0.004 16.1 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase COPIIcoated_ERV PF07970.7 EPY51622.1 - 8.3e-32 110.6 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPY51622.1 - 3.1e-19 68.7 0.0 7.5e-19 67.5 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ATP_bind_3 PF01171.15 EPY51623.1 - 1.3e-19 70.4 0.0 2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 EPY51623.1 - 0.00082 18.0 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase DUF2392 PF10288.4 EPY51623.1 - 0.0009 19.5 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EPY51623.1 - 0.005 16.2 0.9 0.005 16.2 0.6 3.0 4 0 0 4 4 4 1 RecR protein Asn_synthase PF00733.16 EPY51623.1 - 0.034 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase DUF3970 PF13113.1 EPY51623.1 - 0.072 12.7 0.4 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) NAD_synthase PF02540.12 EPY51623.1 - 0.073 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase CK_II_beta PF01214.13 EPY51624.1 - 5.2e-72 241.2 0.0 6.6e-72 240.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1682 PF07946.9 EPY51625.1 - 2.6e-71 240.1 0.1 3.3e-71 239.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Cyt-b5 PF00173.23 EPY51626.1 - 1.4e-23 82.4 0.1 1.9e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ASF1_hist_chap PF04729.8 EPY51626.1 - 0.15 11.7 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 ASF1 like histone chaperone LAMTOR PF15454.1 EPY51627.1 - 0.00059 20.0 0.4 0.00059 20.0 0.3 1.7 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator AAA PF00004.24 EPY51628.1 - 6.2e-16 58.8 0.0 2.2e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 EPY51628.1 - 6.7e-09 35.5 0.4 5e-08 32.7 0.1 2.5 3 0 0 3 3 3 1 BAH domain AAA_22 PF13401.1 EPY51628.1 - 4.2e-08 33.4 0.0 6.6e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPY51628.1 - 2.7e-07 30.7 0.0 1.4e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EPY51628.1 - 0.0003 20.4 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EPY51628.1 - 0.0016 18.2 0.0 0.017 14.8 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase Zot PF05707.7 EPY51628.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Mating_C PF12737.2 EPY51628.1 - 0.012 14.4 0.2 0.017 14.0 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 AAA_19 PF13245.1 EPY51628.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 EPY51628.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EPY51628.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dopey_N PF04118.9 EPY51628.1 - 0.031 13.0 0.3 10 4.7 0.0 3.0 3 0 0 3 3 3 0 Dopey, N-terminal Rad21_Rec8_N PF04825.8 EPY51629.1 - 6.4e-28 96.9 0.1 1.1e-27 96.1 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPY51629.1 - 1.4e-08 33.7 1.7 0.00016 20.8 0.0 3.5 4 0 0 4 4 4 2 Conserved region of Rad21 / Rec8 like protein Mt_ATP-synt_D PF05873.7 EPY51630.1 - 6.2e-11 42.2 0.5 8.6e-11 41.7 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF342 PF03961.8 EPY51630.1 - 0.0066 14.9 0.6 0.0082 14.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 EPY51630.1 - 0.0082 15.9 0.3 0.014 15.2 0.2 1.5 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DapH_N PF08503.5 EPY51630.1 - 0.012 15.7 1.1 0.02 15.0 0.8 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Spc7 PF08317.6 EPY51630.1 - 0.015 13.9 1.3 0.019 13.6 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EPY51630.1 - 0.026 12.2 0.7 0.034 11.8 0.5 1.2 1 0 0 1 1 1 0 Myosin tail Phage_GP20 PF06810.6 EPY51630.1 - 0.04 13.3 1.2 0.29 10.5 0.4 2.2 2 1 0 2 2 2 0 Phage minor structural protein GP20 BLOC1_2 PF10046.4 EPY51630.1 - 0.074 13.1 3.2 4.9 7.3 0.1 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.4 EPY51630.1 - 0.1 12.5 0.8 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA NPV_P10 PF05531.7 EPY51630.1 - 0.14 12.4 1.7 1.2 9.4 0.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2408 PF10303.4 EPY51630.1 - 0.16 12.0 0.7 0.29 11.2 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) CENP-F_leu_zip PF10473.4 EPY51630.1 - 0.17 11.7 1.2 0.28 11.0 0.6 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1014 PF06244.7 EPY51631.1 - 1.6e-28 99.3 10.3 3e-28 98.4 7.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) VPS9 PF02204.13 EPY51632.1 - 1.5e-22 79.5 0.3 4.2e-22 78.1 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Glyco_transf_8C PF08437.5 EPY51632.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal SEN1_N PF12726.2 EPY51633.1 - 1e-110 371.0 30.1 1.7e-110 370.2 20.9 1.4 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EPY51633.1 - 6.9e-71 238.5 2.2 6.9e-71 238.5 1.5 3.3 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EPY51633.1 - 2.3e-62 209.9 2.2 2.7e-62 209.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPY51633.1 - 2.4e-11 43.1 0.0 6.6e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPY51633.1 - 2e-08 34.0 0.7 2.1e-05 24.1 0.0 3.4 3 1 1 4 4 4 2 AAA domain UvrD_C_2 PF13538.1 EPY51633.1 - 0.0043 17.1 0.0 0.015 15.4 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 EPY51633.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro_72 PF03198.9 EPY51635.1 - 4.5e-126 420.0 9.7 5.6e-126 419.7 6.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPY51635.1 - 1e-13 51.5 1.0 3.1e-13 50.0 0.7 1.8 1 0 0 1 1 1 1 X8 domain ELYS PF13934.1 EPY51637.1 - 3e-48 164.5 3.6 3.9e-48 164.1 2.5 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly XPG_N PF00752.12 EPY51638.1 - 1.9e-31 108.3 0.0 3.7e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPY51638.1 - 8.4e-23 80.2 0.0 1.8e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EPY51638.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing SMC_N PF02463.14 EPY51639.1 - 6.8e-67 224.9 0.0 1.1e-66 224.2 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPY51639.1 - 1.3e-30 105.7 0.0 5.5e-30 103.7 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPY51639.1 - 3.7e-13 50.0 0.3 2.6e-08 34.1 0.1 4.5 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EPY51639.1 - 4.9e-08 32.3 0.3 1.3e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EPY51639.1 - 0.003 17.4 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit YqgF PF14639.1 EPY51639.1 - 0.0051 16.3 2.8 0.0088 15.6 0.2 2.8 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 AAA_15 PF13175.1 EPY51639.1 - 0.045 12.7 0.0 0.045 12.7 0.0 4.7 3 2 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 EPY51639.1 - 0.14 12.4 0.0 0.14 12.4 0.0 6.3 4 2 0 4 4 4 0 ABC transporter CAF1A PF12253.3 EPY51640.1 - 8.1e-21 73.9 7.4 8.1e-21 73.9 5.2 2.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EPY51640.1 - 1.1e-15 57.6 51.9 2e-15 56.7 36.0 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CUE PF02845.11 EPY51640.1 - 0.0087 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain RRM_1 PF00076.17 EPY51641.1 - 2.9e-19 68.4 0.0 3.2e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51641.1 - 3.5e-13 49.3 0.0 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1841 PF08897.6 EPY51641.1 - 0.00025 20.8 0.8 0.0008 19.2 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1841) RRM_5 PF13893.1 EPY51641.1 - 0.0016 18.2 0.1 0.36 10.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EPY51642.1 - 1.5e-65 220.7 0.0 2.2e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPY51642.1 - 2.5e-30 105.3 0.2 5.1e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EPY51642.1 - 1.1e-21 77.4 0.0 2.3e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Spc97_Spc98 PF04130.8 EPY51644.1 - 6e-122 407.7 17.7 7.5e-122 407.3 12.2 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Epimerase PF01370.16 EPY51645.1 - 2.9e-49 167.6 0.0 3.6e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPY51645.1 - 1.3e-25 89.0 0.2 2.4e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EPY51645.1 - 6.3e-16 57.9 0.0 1.3e-15 56.8 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPY51645.1 - 2.6e-13 49.5 0.0 7e-13 48.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPY51645.1 - 1.9e-11 44.2 0.0 3.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPY51645.1 - 3e-09 37.1 0.0 5.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPY51645.1 - 8.5e-09 34.7 0.0 2.4e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPY51645.1 - 1.5e-08 33.8 0.0 2.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EPY51645.1 - 1.2e-07 31.5 0.0 3.4e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EPY51645.1 - 0.00017 20.8 0.0 0.00033 19.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EPY51645.1 - 0.0035 16.7 0.1 0.0059 16.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 EPY51645.1 - 0.019 13.9 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EPY51645.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 EPY51645.1 - 0.057 13.1 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.15 EPY51645.1 - 0.12 12.3 0.1 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ran_BP1 PF00638.13 EPY51646.1 - 9.5e-20 70.8 0.0 9.5e-20 70.8 0.0 1.7 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 EPY51646.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 WH1 domain Ish1 PF10281.4 EPY51647.1 - 1.8e-41 139.7 20.4 9.4e-07 28.8 0.1 7.8 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EPY51647.1 - 8.1e-08 31.5 0.0 0.042 13.3 0.0 5.7 6 0 0 6 6 6 2 SAP domain HeH PF12949.2 EPY51647.1 - 0.00018 20.9 0.2 8.6 6.0 0.0 4.8 5 0 0 5 5 5 2 HeH/LEM domain SAP30_Sin3_bdg PF13867.1 EPY51647.1 - 0.0016 18.2 0.2 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 LEM PF03020.10 EPY51647.1 - 0.005 16.2 0.1 3.5 7.1 0.0 3.8 4 0 0 4 4 4 1 LEM domain DUF883 PF05957.8 EPY51647.1 - 0.026 14.9 22.8 2.3 8.6 1.2 5.5 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EPY51647.1 - 0.47 10.8 30.3 21 5.5 2.4 6.7 4 2 1 5 5 5 0 YtxH-like protein GRIP PF01465.15 EPY51648.1 - 1.9e-11 43.2 0.3 6.1e-11 41.6 0.2 1.9 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EPY51648.1 - 0.00087 18.9 13.2 0.00087 18.9 9.2 2.2 1 1 1 2 2 2 1 IncA protein Kinesin-relat_1 PF12711.2 EPY51648.1 - 0.0021 18.4 9.0 0.0021 18.4 6.3 3.2 2 1 1 3 3 3 1 Kinesin motor DUF904 PF06005.7 EPY51648.1 - 0.0097 16.1 11.1 0.0097 16.1 7.7 3.8 1 1 3 4 4 4 1 Protein of unknown function (DUF904) CCDC155 PF14662.1 EPY51648.1 - 0.064 12.8 25.7 0.069 12.7 16.6 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 RTBV_P46 PF06216.6 EPY51648.1 - 0.075 11.8 4.9 0.078 11.8 2.7 1.4 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein FlaC_arch PF05377.6 EPY51648.1 - 2.5 8.0 15.8 5.4 6.9 0.4 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4279 PF14106.1 EPY51648.1 - 2.9 7.7 7.0 0.69 9.8 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4279) RNase_HII PF01351.13 EPY51648.1 - 4.9 6.7 11.0 0.48 10.0 4.3 1.8 2 1 0 2 2 2 0 Ribonuclease HII hDGE_amylase PF14701.1 EPY51648.1 - 8.8 5.1 12.9 8.8 5.1 8.1 1.6 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Actin PF00022.14 EPY51649.1 - 6.3e-66 222.4 0.0 4.2e-37 127.5 0.0 2.5 2 1 0 3 3 3 2 Actin DUF3793 PF12672.2 EPY51649.1 - 0.019 14.5 2.3 0.4 10.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) Kin17_mid PF10357.4 EPY51650.1 - 2.2e-50 169.5 3.5 2.2e-50 169.5 2.4 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EPY51650.1 - 0.00016 21.7 2.7 0.00041 20.4 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPY51650.1 - 0.00052 20.0 1.9 0.0013 18.8 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1675 PF07897.6 EPY51650.1 - 0.01 15.7 7.6 0.015 15.2 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1672 PF07901.6 EPY51650.1 - 0.015 14.3 2.3 0.024 13.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) zf-C2H2_2 PF12756.2 EPY51650.1 - 0.023 14.7 0.2 0.023 14.7 0.1 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) PAPA-1 PF04795.7 EPY51650.1 - 2.6 8.8 12.7 0.14 12.8 3.5 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region DER1 PF04511.10 EPY51651.1 - 5.2e-35 120.7 11.5 6.3e-35 120.4 8.0 1.0 1 0 0 1 1 1 1 Der1-like family DUF2427 PF10348.4 EPY51651.1 - 1.8 8.1 7.7 0.12 12.0 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) TMF_TATA_bd PF12325.3 EPY51652.1 - 3.2e-27 94.6 11.6 3.2e-27 94.6 8.1 4.6 2 1 2 4 4 4 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EPY51652.1 - 2.5e-11 43.2 9.7 2.5e-11 43.2 6.7 6.6 2 2 3 6 6 6 2 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 EPY51652.1 - 0.026 14.5 2.2 0.026 14.5 1.5 5.6 2 2 4 6 6 6 0 Flagellar FliJ protein Rad60-SLD PF11976.3 EPY51653.1 - 1.4e-24 85.5 0.2 2.1e-24 84.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPY51653.1 - 6.1e-10 38.3 0.1 9.1e-10 37.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family KH_4 PF13083.1 EPY51653.1 - 0.1 12.2 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 KH domain Slu7 PF11708.3 EPY51654.1 - 3.6e-50 170.9 7.7 5.2e-50 170.4 5.3 1.2 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EPY51654.1 - 0.13 11.9 0.7 0.31 10.7 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3128 PF11326.3 EPY51654.1 - 0.14 12.3 1.7 0.43 10.7 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) RRM_6 PF14259.1 EPY51655.1 - 2.3e-12 46.7 0.0 4.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY51655.1 - 5.7e-11 41.8 0.2 1.6e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L21e PF01157.13 EPY51656.1 - 2e-40 136.5 5.3 3.3e-40 135.9 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e BCNT PF07572.7 EPY51656.1 - 0.068 13.1 1.0 0.11 12.4 0.7 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development UbiA PF01040.13 EPY51657.1 - 2.7e-29 102.1 19.8 3.8e-29 101.6 13.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family CRAL_TRIO PF00650.15 EPY51658.1 - 1.7e-22 79.5 0.0 3.5e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPY51658.1 - 2.3e-10 40.4 0.1 9.5e-10 38.4 0.1 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPY51658.1 - 3.8e-07 30.1 0.0 8.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Isochorismatase PF00857.15 EPY51659.1 - 4.1e-26 91.9 0.0 4.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Arrestin_C PF02752.17 EPY51660.1 - 5.4e-07 29.7 0.1 1.5e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pkinase PF00069.20 EPY51661.1 - 8.8e-38 129.9 0.0 1.6e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51661.1 - 8.1e-32 110.2 0.0 2e-31 108.9 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51661.1 - 0.003 16.5 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPY51661.1 - 0.19 11.4 0.0 0.96 9.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RCC1 PF00415.13 EPY51662.1 - 4.5e-64 212.4 4.9 1.7e-14 53.7 0.0 8.2 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPY51662.1 - 3e-36 122.2 29.0 6.6e-08 31.9 1.5 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EPY51662.1 - 0.0002 20.7 2.7 14 5.2 0.0 4.9 5 0 0 5 5 5 3 Putative carbohydrate binding domain Kelch_2 PF07646.10 EPY51662.1 - 0.017 14.8 0.0 6.5 6.6 0.0 3.7 3 0 0 3 3 3 0 Kelch motif DUF4213 PF13938.1 EPY51662.1 - 0.15 12.2 0.1 6.5 6.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) DUF2458 PF10454.4 EPY51663.1 - 8.1e-30 103.6 5.0 1.4e-29 102.9 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 EPY51663.1 - 1.8e-05 24.2 3.2 3.2e-05 23.5 2.2 1.3 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Guanylin PF02058.10 EPY51663.1 - 0.0011 18.9 2.7 0.18 11.8 0.4 2.3 2 0 0 2 2 2 2 Guanylin precursor MipZ PF09140.6 EPY51663.1 - 0.051 12.6 0.2 0.092 11.8 0.1 1.4 1 0 0 1 1 1 0 ATPase MipZ ATP-synt_F PF01990.12 EPY51663.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit Fib_alpha PF08702.5 EPY51663.1 - 3.6 7.6 9.2 3.5 7.7 0.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RhoGAP PF00620.22 EPY51664.1 - 1.9e-38 131.4 0.0 2.8e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EPY51664.1 - 0.0027 16.5 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) His_Phos_2 PF00328.17 EPY51665.1 - 5.2e-46 157.5 0.0 6.3e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 EPY51666.1 - 3.5e-66 222.9 0.0 5e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51666.1 - 3.4e-44 150.8 0.0 5.2e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51666.1 - 1.6e-05 24.0 0.0 4.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPY51666.1 - 0.025 13.9 0.0 0.074 12.3 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Endonuclease_5 PF04493.9 EPY51666.1 - 0.054 12.8 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease V Kdo PF06293.9 EPY51666.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RICTOR_N PF14664.1 EPY51668.1 - 3.9e-89 298.8 2.6 2e-88 296.4 0.9 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EPY51668.1 - 4.7e-88 294.0 5.3 1.9e-84 282.1 2.6 3.8 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EPY51668.1 - 1.6e-33 115.0 0.5 5.3e-32 110.1 0.1 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EPY51668.1 - 1.3e-27 95.5 0.3 3.5e-25 87.7 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EPY51668.1 - 0.0023 18.1 0.1 2.2 8.6 0.0 3.5 2 0 0 2 2 2 1 HEAT repeats Syntaxin PF00804.20 EPY51668.1 - 0.075 13.2 4.2 0.084 13.0 1.3 2.3 2 0 0 2 2 2 0 Syntaxin FAD_binding_1 PF00667.15 EPY51669.1 - 1.9e-58 197.4 0.0 3e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPY51669.1 - 2.2e-12 47.5 0.0 1.1e-10 42.0 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain ox_reductase_C PF08635.5 EPY51671.1 - 1.4e-70 235.2 0.0 1.9e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EPY51671.1 - 4.8e-18 65.8 0.0 7.3e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPY51671.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain SH3_9 PF14604.1 EPY51672.1 - 2.5e-22 78.1 0.1 3e-12 45.9 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EPY51672.1 - 5.1e-22 77.8 2.8 5.1e-22 77.8 1.9 3.1 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EPY51672.1 - 3e-17 61.7 0.0 1.5e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EPY51672.1 - 1e-15 56.9 0.1 7.8e-10 38.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EPY51672.1 - 3.9e-08 32.9 8.1 3.9e-08 32.9 5.6 2.2 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4407 PF14362.1 EPY51672.1 - 0.28 10.1 2.4 10 4.9 2.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) IncA PF04156.9 EPY51672.1 - 2.5 7.6 19.4 1.2 8.7 5.7 3.4 4 0 0 4 4 4 0 IncA protein DEAD PF00270.24 EPY51673.1 - 1.2e-36 125.7 1.3 1.7e-36 125.2 0.4 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY51673.1 - 1.4e-23 82.5 0.1 2.8e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EPY51673.1 - 0.0076 16.2 0.0 0.27 11.1 0.0 2.8 3 0 0 3 3 3 1 Helicase C-terminal domain AAA_30 PF13604.1 EPY51673.1 - 0.033 13.7 0.1 0.11 12.1 0.1 1.9 2 1 0 2 2 2 0 AAA domain Abhydrolase_8 PF06259.7 EPY51673.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Spermine_synth PF01564.12 EPY51674.1 - 1.5e-99 331.9 0.0 1.8e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EPY51674.1 - 0.00023 21.7 0.0 0.00039 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY51674.1 - 0.0022 17.5 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EPY51674.1 - 0.032 15.0 0.0 0.071 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 EPY51674.1 - 0.036 13.7 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EPY51674.1 - 0.045 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EPY51674.1 - 0.12 11.5 0.3 0.66 9.1 0.1 2.2 2 1 0 2 2 2 0 O-methyltransferase MTS PF05175.9 EPY51674.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain 60KD_IMP PF02096.15 EPY51675.1 - 8.9e-43 146.2 5.1 8.9e-43 146.2 3.6 1.4 2 0 0 2 2 2 1 60Kd inner membrane protein DUF1049 PF06305.6 EPY51675.1 - 0.39 10.2 2.2 2.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) WD40 PF00400.27 EPY51676.1 - 1.4e-55 183.2 11.4 9.6e-11 41.1 0.1 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat PQQ_2 PF13360.1 EPY51676.1 - 5.9e-08 32.4 1.0 0.00012 21.6 0.1 2.6 2 1 0 2 2 2 2 PQQ-like domain eIF2A PF08662.6 EPY51676.1 - 2.5e-07 30.5 0.7 0.069 12.8 0.1 3.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EPY51676.1 - 0.0026 17.9 6.1 4.3 7.7 0.0 5.1 4 1 1 5 5 5 2 PQQ-like domain IKI3 PF04762.7 EPY51676.1 - 0.0071 14.2 1.0 0.76 7.5 0.0 2.9 3 1 1 4 4 4 2 IKI3 family CPSF_A PF03178.10 EPY51676.1 - 0.013 14.6 0.1 0.083 11.9 0.0 2.3 1 1 1 2 2 2 0 CPSF A subunit region PQQ PF01011.16 EPY51676.1 - 0.16 11.5 0.7 22 4.7 0.0 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat SH3_1 PF00018.23 EPY51677.1 - 4.8e-08 32.2 0.1 8.4e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Transglut_core PF01841.14 EPY51677.1 - 5.9e-08 32.9 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EPY51677.1 - 3.1e-06 26.5 0.1 5.4e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPY51677.1 - 0.00097 18.6 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Acetyltransf_2 PF00797.12 EPY51677.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase Abhydrolase_2 PF02230.11 EPY51679.1 - 3.1e-40 137.9 0.0 3.5e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydro_lipase PF04083.11 EPY51679.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pkinase PF00069.20 EPY51680.1 - 8.8e-65 218.4 0.0 2.1e-64 217.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51680.1 - 3.5e-47 160.6 0.0 1.4e-46 158.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51680.1 - 0.0018 17.3 0.0 0.03 13.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like U3snoRNP10 PF12397.3 EPY51680.1 - 0.32 10.9 1.8 2.1 8.3 0.1 2.7 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 MOZART1 PF12554.3 EPY51681.1 - 1.8e-18 65.7 1.1 2.1e-18 65.4 0.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 EPY51681.1 - 0.00045 19.7 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated p450 PF00067.17 EPY51681.1 - 0.077 11.5 0.0 0.077 11.5 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 Exo_endo_phos PF03372.18 EPY51682.1 - 9.8e-27 94.4 0.1 1.6e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA_4 PF14555.1 EPY51682.1 - 0.00087 18.7 0.1 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Septin PF00735.13 EPY51683.1 - 2e-108 361.7 0.3 3.1e-108 361.0 0.2 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EPY51683.1 - 3.3e-06 26.6 0.0 7e-05 22.3 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPY51683.1 - 1.5e-05 24.2 0.5 4.1e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPY51683.1 - 9.4e-05 22.3 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPY51683.1 - 0.00023 21.3 0.1 0.003 17.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EPY51683.1 - 0.0046 16.1 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 AIG1 family AAA_24 PF13479.1 EPY51683.1 - 0.005 16.4 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPY51683.1 - 0.0085 16.3 0.4 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 EPY51683.1 - 0.015 15.4 0.3 0.14 12.3 0.0 2.6 2 1 1 3 3 3 0 RNA helicase Gtr1_RagA PF04670.7 EPY51683.1 - 0.023 13.8 0.0 0.05 12.7 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Miro PF08477.8 EPY51683.1 - 0.037 14.5 0.1 0.14 12.6 0.0 2.1 2 0 0 2 2 1 0 Miro-like protein AAA_33 PF13671.1 EPY51683.1 - 0.047 13.5 0.2 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPY51683.1 - 0.09 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EPY51683.1 - 0.1 12.0 0.8 0.59 9.6 0.1 2.5 2 2 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EPY51683.1 - 0.37 10.6 3.4 6 6.6 0.0 2.9 2 1 1 3 3 3 0 Dynamin family GCD14 PF08704.5 EPY51684.1 - 1e-100 336.3 0.0 1.3e-100 335.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EPY51684.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EPY51684.1 - 0.0088 16.6 0.0 0.022 15.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY51684.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DMAP1 PF05499.7 EPY51685.1 - 4.4e-05 23.0 2.4 0.00082 18.9 1.7 2.3 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.26 EPY51685.1 - 0.00017 21.5 1.3 0.00035 20.5 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY51685.1 - 0.00096 19.2 0.2 0.00096 19.2 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Dynamin_M PF01031.15 EPY51686.1 - 1.1e-107 359.2 1.8 8.4e-107 356.3 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EPY51686.1 - 2.1e-55 187.0 0.1 2.1e-55 187.0 0.1 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 EPY51686.1 - 5.3e-26 90.3 6.4 5.3e-26 90.3 4.4 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPY51686.1 - 0.00078 19.3 1.2 0.0032 17.4 0.2 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPY51686.1 - 0.072 13.5 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Strep_SA_rep PF06696.6 EPY51686.1 - 9.4 6.1 6.5 1.5 8.6 1.8 1.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat PAP_assoc PF03828.14 EPY51687.1 - 1.1e-09 38.1 0.2 3.8e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPY51687.1 - 2.9e-07 30.7 0.3 1.3e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_central PF04928.12 EPY51687.1 - 1.3e-06 27.4 0.2 0.019 13.7 0.1 2.7 2 0 0 2 2 2 2 Poly(A) polymerase central domain rRNA_proc-arch PF13234.1 EPY51688.1 - 1.3e-70 237.6 3.4 2.3e-70 236.8 2.4 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EPY51688.1 - 3.1e-55 186.1 0.0 7e-55 185.0 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPY51688.1 - 2.4e-22 79.2 0.0 6e-21 74.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY51688.1 - 1.5e-05 24.7 0.0 4.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RanBP PF00641.13 EPY51690.1 - 7.5e-19 66.5 26.8 5e-09 35.1 0.5 4.4 4 0 0 4 4 4 3 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EPY51690.1 - 2.8e-08 33.2 0.0 5.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51690.1 - 9.8e-07 28.6 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51690.1 - 0.026 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4211 PF13926.1 EPY51691.1 - 1.3e-28 99.3 0.2 6.5e-28 97.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Ebp2 PF05890.7 EPY51692.1 - 2.3e-79 266.5 24.5 2.3e-79 266.5 17.0 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 SRP9-21 PF05486.7 EPY51693.1 - 4.7e-23 80.7 0.3 6.3e-23 80.3 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Mito_carr PF00153.22 EPY51694.1 - 1.2e-59 198.0 1.5 1.2e-22 79.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 EPY51695.1 - 1.3e-58 197.0 0.1 1.7e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY51695.1 - 4.8e-21 75.4 0.0 8.4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY51695.1 - 3e-09 36.3 0.0 3.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPY51695.1 - 1e-06 28.3 0.1 1.2e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY51695.1 - 0.00014 21.8 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPY51695.1 - 0.0051 16.0 0.5 0.01 15.0 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EPY51695.1 - 0.035 13.6 0.3 0.56 9.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 EPY51695.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_25 PF13481.1 EPY51695.1 - 0.075 12.4 0.1 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Gemini_AL1 PF00799.15 EPY51695.1 - 0.078 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain DUF2075 PF09848.4 EPY51695.1 - 0.078 11.9 0.0 0.17 10.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1366 PF07104.6 EPY51695.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) CPSF_A PF03178.10 EPY51696.1 - 4.5e-61 206.7 2.9 2.6e-59 200.8 0.1 3.3 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 EPY51696.1 - 7.3e-49 166.2 6.9 1.4e-48 165.2 4.8 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4597 PF15366.1 EPY51696.1 - 0.12 12.0 0.0 0.39 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) Cofilin_ADF PF00241.15 EPY51697.1 - 1.3e-13 50.9 0.2 1.4e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ribosomal_L50 PF10501.4 EPY51697.1 - 0.02 14.8 0.1 0.048 13.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal subunit 39S FAD_binding_6 PF00970.19 EPY51698.1 - 5e-14 52.2 0.0 7.8e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPY51698.1 - 0.0001 22.8 0.0 0.00023 21.6 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain PDZ_1 PF12812.2 EPY51698.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 PDZ-like domain AA_kinase PF00696.23 EPY51699.1 - 2e-38 132.2 0.4 3e-38 131.7 0.3 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EPY51699.1 - 3.2e-15 55.5 0.2 6.5e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 PUA domain Thioredoxin PF00085.15 EPY51700.1 - 3.1e-56 187.4 0.0 2.8e-28 97.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EPY51700.1 - 7.7e-20 71.3 0.9 1.5e-19 70.4 0.6 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EPY51700.1 - 1.5e-12 47.6 2.9 0.00013 22.0 0.1 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPY51700.1 - 6.5e-12 45.4 0.1 0.00018 21.5 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EPY51700.1 - 6.6e-09 35.5 0.0 0.00029 20.5 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 EPY51700.1 - 8.4e-09 35.3 0.0 0.0013 18.7 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.8 EPY51700.1 - 9.1e-08 32.0 0.5 0.0011 18.9 0.1 2.5 2 0 0 2 2 2 2 ERp29, N-terminal domain Redoxin PF08534.5 EPY51700.1 - 6.7e-06 25.7 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 EPY51700.1 - 1e-05 25.4 1.7 0.0014 18.4 0.1 3.5 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EPY51700.1 - 0.00033 20.2 0.2 0.46 10.0 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin DnaI_N PF07319.6 EPY51700.1 - 0.036 14.3 0.1 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus DDE_Tnp_1_2 PF13586.1 EPY51700.1 - 0.051 13.7 0.0 5.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Transposase DDE domain TraF PF13728.1 EPY51700.1 - 0.068 12.6 0.4 10 5.5 0.0 2.6 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EPY51700.1 - 0.1 12.6 2.3 8.9 6.2 0.0 3.3 3 1 0 3 3 3 0 Thioredoxin CAS_CSE1 PF03378.10 EPY51700.1 - 0.11 10.7 0.1 0.44 8.8 0.0 1.8 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus Tom22 PF04281.8 EPY51701.1 - 8.6e-44 148.3 1.3 9.7e-44 148.2 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF3722 PF12519.3 EPY51702.1 - 3.9e-70 236.0 0.1 6.3e-70 235.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) WD40 PF00400.27 EPY51703.1 - 1.9e-26 90.9 25.2 9.1e-07 28.5 0.1 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EPY51703.1 - 8.8e-05 20.8 9.7 0.1 10.6 0.6 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 EPY51703.1 - 0.0018 18.0 1.3 7.2 6.2 0.0 3.3 3 0 0 3 3 3 2 Transcription factor IIIC subunit delta N-term Tox-GHH PF15636.1 EPY51703.1 - 0.051 13.2 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin STAG PF08514.6 EPY51704.1 - 1e-37 128.4 1.3 1e-37 128.4 0.9 2.4 2 0 0 2 2 2 1 STAG domain HEAT PF02985.17 EPY51704.1 - 0.015 15.3 0.2 1.6 9.0 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Roughex PF06020.6 EPY51705.1 - 1.1 7.9 4.5 3.2 6.3 3.3 1.5 2 0 0 2 2 2 0 Drosophila roughex protein MDH PF02315.11 EPY51705.1 - 3.1 7.7 8.9 0.28 11.1 1.8 2.3 1 1 1 2 2 2 0 Methanol dehydrogenase beta subunit DUF4228 PF14009.1 EPY51705.1 - 4.1 7.4 8.7 4.7 7.3 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) CAP_GLY PF01302.20 EPY51706.1 - 1.2e-13 50.4 1.9 1.6e-13 50.1 0.6 1.8 2 0 0 2 2 2 1 CAP-Gly domain Atg14 PF10186.4 EPY51706.1 - 0.0002 20.4 12.5 0.0002 20.4 8.7 2.5 1 1 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EPY51706.1 - 0.00098 18.8 22.6 0.0014 18.3 0.5 3.1 2 1 0 2 2 2 1 Mnd1 family GAS PF13851.1 EPY51706.1 - 0.0018 17.5 14.4 0.0018 17.5 10.0 2.5 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EPY51706.1 - 0.047 13.5 32.8 0.2 11.5 1.5 3.8 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1492 PF07374.6 EPY51706.1 - 0.087 12.9 2.7 0.079 13.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Filament PF00038.16 EPY51706.1 - 0.25 10.7 25.3 1.3 8.3 0.5 3.5 1 1 2 3 3 3 0 Intermediate filament protein Z1 PF10593.4 EPY51706.1 - 0.58 9.3 6.9 0.094 11.9 2.0 1.7 2 0 0 2 2 2 0 Z1 domain Exonuc_VII_L PF02601.10 EPY51706.1 - 0.82 8.8 17.8 0.037 13.2 6.7 2.0 1 1 0 2 2 2 0 Exonuclease VII, large subunit HR1 PF02185.11 EPY51706.1 - 1.1 9.0 16.6 2.1 8.1 1.0 4.7 2 1 1 4 4 4 0 Hr1 repeat FUSC PF04632.7 EPY51706.1 - 1.4 7.2 7.6 1.7 6.9 4.4 1.6 1 1 0 2 2 2 0 Fusaric acid resistance protein family Med10 PF09748.4 EPY51706.1 - 1.7 8.5 10.3 3.6e+02 0.9 7.2 3.1 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex OmpH PF03938.9 EPY51706.1 - 2.6 7.9 11.5 0.61 10.0 5.5 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Phage_GP20 PF06810.6 EPY51706.1 - 2.6 7.4 12.1 0.085 12.2 3.0 2.4 3 1 1 4 4 3 0 Phage minor structural protein GP20 MCPsignal PF00015.16 EPY51706.1 - 3.6 7.0 8.8 1.2 8.6 2.2 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TBPIP PF07106.8 EPY51706.1 - 4.2 6.8 25.5 2.6 7.5 0.9 3.2 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4559 PF15112.1 EPY51706.1 - 4.7 6.2 17.0 5.4 6.0 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4559) Tropomyosin_1 PF12718.2 EPY51706.1 - 7.7 6.3 29.7 0.69 9.7 9.3 3.3 2 2 2 4 4 4 0 Tropomyosin like DUF883 PF05957.8 EPY51706.1 - 9.3 6.7 12.7 0.25 11.7 3.2 2.5 4 0 0 4 4 2 0 Bacterial protein of unknown function (DUF883) G6PD_C PF02781.11 EPY51707.1 - 1e-77 260.9 0.0 1.8e-77 260.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EPY51707.1 - 1.5e-45 155.7 0.3 1.1e-33 116.9 0.1 2.5 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain VD10_N PF08476.5 EPY51707.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Viral D10 N-terminal Flavodoxin_1 PF00258.20 EPY51708.1 - 1.2e-07 31.8 0.1 2e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EPY51708.1 - 0.00028 20.4 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EPY51708.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold SNF2_N PF00176.18 EPY51709.1 - 3.5e-58 196.7 0.1 5.4e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY51709.1 - 9.7e-15 54.1 0.0 5.2e-13 48.6 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY51709.1 - 3.1e-06 27.1 0.3 1.4e-05 24.9 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit LOH1CR12 PF10158.4 EPY51710.1 - 0.14 11.9 5.4 0.57 9.9 0.5 2.4 1 1 1 2 2 2 0 Tumour suppressor protein DUF1192 PF06698.6 EPY51710.1 - 1.1 9.1 4.6 0.37 10.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) F_actin_cap_B PF01115.12 EPY51711.1 - 3.2e-93 311.3 0.0 3.6e-93 311.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.12 EPY51711.1 - 0.053 12.5 0.1 2 7.4 0.0 2.2 2 1 0 2 2 2 0 F-actin capping protein alpha subunit Bromodomain PF00439.20 EPY51712.1 - 3.7e-47 158.1 0.2 8e-24 83.3 0.2 2.7 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 EPY51713.1 - 4.4e-19 68.4 0.2 4.4e-19 68.4 0.1 1.9 3 0 0 3 3 3 1 Dip2/Utp12 Family TFIIA PF03153.8 EPY51713.1 - 0.53 10.1 20.5 1.4 8.6 14.1 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2407_C PF13373.1 EPY51714.1 - 2.8e-25 88.8 7.3 4.9e-24 84.8 5.1 2.2 1 1 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EPY51714.1 - 2e-16 59.9 0.0 5.3e-16 58.5 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EPY51714.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ABC_tran PF00005.22 EPY51715.1 - 2.7e-58 196.1 0.7 2.3e-34 118.6 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EPY51715.1 - 1.7e-19 70.9 0.0 5.1e-08 33.2 0.1 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EPY51715.1 - 2.4e-14 53.1 0.0 0.00014 21.1 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPY51715.1 - 3.9e-08 32.7 0.0 0.0053 16.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.19 EPY51715.1 - 5.8e-08 32.2 0.1 1.4e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Miro PF08477.8 EPY51715.1 - 1.7e-07 31.7 0.0 0.02 15.3 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EPY51715.1 - 5.8e-07 30.3 0.0 0.07 13.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPY51715.1 - 6.5e-07 29.0 0.1 0.15 11.4 0.0 4.2 4 0 0 4 4 4 1 AAA-like domain MobB PF03205.9 EPY51715.1 - 9.7e-07 28.5 0.0 0.14 11.8 0.0 3.5 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EPY51715.1 - 1.7e-06 27.3 1.7 0.022 13.8 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.18 EPY51715.1 - 2.4e-06 27.5 0.0 0.093 12.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EPY51715.1 - 2.6e-06 27.9 8.0 0.037 14.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPY51715.1 - 7.1e-06 25.2 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPY51715.1 - 1.9e-05 24.7 0.0 0.1 12.7 0.0 3.7 4 0 0 4 4 2 1 AAA domain NACHT PF05729.7 EPY51715.1 - 2.7e-05 23.8 0.0 0.066 12.8 0.0 2.9 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 EPY51715.1 - 3.6e-05 23.7 0.0 0.46 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPY51715.1 - 4.3e-05 23.0 0.0 0.14 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPY51715.1 - 0.00017 21.6 4.3 0.5 10.3 0.0 3.7 3 2 0 3 3 3 2 AAA ATPase domain ArgK PF03308.11 EPY51715.1 - 0.00018 20.4 0.1 0.26 10.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 EPY51715.1 - 0.00022 21.0 0.0 0.53 10.2 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 EPY51715.1 - 0.00042 20.1 0.8 0.78 9.5 0.0 3.4 3 1 0 3 3 2 1 Dynamin family CLASP_N PF12348.3 EPY51715.1 - 0.00045 19.6 0.1 0.033 13.5 0.0 2.9 3 0 0 3 3 3 1 CLASP N terminal RNA_helicase PF00910.17 EPY51715.1 - 0.00053 20.1 0.0 1.5 8.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EPY51715.1 - 0.00071 19.4 0.0 1.7 8.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 EPY51715.1 - 0.00074 19.7 0.1 1.2 9.3 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPY51715.1 - 0.00092 18.9 1.4 0.49 10.0 0.0 2.8 3 0 0 3 3 2 1 Archaeal ATPase DUF87 PF01935.12 EPY51715.1 - 0.0012 18.7 4.9 0.0075 16.1 0.1 3.4 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_14 PF13173.1 EPY51715.1 - 0.0013 18.6 0.0 2.4 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.1 EPY51715.1 - 0.0022 18.4 5.9 1.7 9.2 0.0 5.2 5 0 0 5 5 4 1 HEAT-like repeat HEAT PF02985.17 EPY51715.1 - 0.0022 17.9 2.8 0.68 10.1 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat AAA_30 PF13604.1 EPY51715.1 - 0.0032 17.0 0.1 4.9 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EPY51715.1 - 0.004 16.8 0.1 0.72 9.6 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 EPY51715.1 - 0.0067 15.3 0.0 1 8.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EPY51715.1 - 0.007 15.8 0.1 0.52 9.7 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EPY51715.1 - 0.0092 15.4 0.0 0.34 10.3 0.0 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_2 PF13646.1 EPY51715.1 - 0.016 15.5 7.9 0.031 14.5 0.0 4.2 3 2 1 4 4 4 0 HEAT repeats Viral_helicase1 PF01443.13 EPY51715.1 - 0.026 14.0 0.0 4.2 6.8 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.22 EPY51715.1 - 0.028 13.8 0.2 6.3 6.1 0.0 3.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EPY51715.1 - 0.034 13.6 0.0 12 5.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EPY51715.1 - 0.048 13.9 0.0 8.1 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EPY51715.1 - 0.049 13.3 0.1 9.7 5.8 0.0 2.9 3 0 0 3 3 2 0 NTPase cobW PF02492.14 EPY51715.1 - 0.061 12.7 0.0 8.5 5.7 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EPY51715.1 - 0.074 12.5 0.0 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Vac14_Fab1_bd PF12755.2 EPY51715.1 - 0.079 13.3 0.0 26 5.2 0.0 3.2 3 0 0 3 3 2 0 Vacuolar 14 Fab1-binding region AAA_13 PF13166.1 EPY51715.1 - 0.094 11.1 4.9 6.3 5.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EPY51715.1 - 0.11 12.0 0.4 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EPY51715.1 - 0.12 11.1 1.3 2.7 6.7 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain ATE_C PF04377.10 EPY51716.1 - 2.5e-45 153.6 2.7 4.3e-45 152.8 1.9 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EPY51716.1 - 2.2e-23 81.8 2.3 3.3e-23 81.2 0.7 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Pkinase PF00069.20 EPY51717.1 - 1.6e-62 210.9 0.0 2.6e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51717.1 - 1.2e-31 109.7 0.0 3.5e-31 108.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Glyco_hydro_76 PF03663.9 EPY51718.1 - 1.1e-43 150.0 11.3 1.5e-43 149.6 7.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.6 EPY51718.1 - 0.0059 15.6 0.7 9.8 5.0 0.0 2.4 1 1 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Fungal_trans PF04082.13 EPY51720.1 - 9.9e-33 113.1 0.4 3.5e-32 111.3 0.3 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY51720.1 - 1.1e-05 25.1 10.3 2.4e-05 24.1 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_25 PF13481.1 EPY51721.1 - 1.7e-05 24.3 0.0 0.00028 20.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad51 PF08423.6 EPY51721.1 - 0.00012 21.0 0.1 0.012 14.5 0.0 2.7 3 0 0 3 3 3 1 Rad51 IstB_IS21 PF01695.12 EPY51721.1 - 0.00022 20.6 0.0 0.00051 19.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RecA PF00154.16 EPY51721.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_10 PF12846.2 EPY51721.1 - 0.014 14.8 0.1 0.17 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA-like domain KaiC PF06745.8 EPY51721.1 - 0.016 14.3 0.2 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.1 EPY51721.1 - 0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPY51721.1 - 0.055 13.4 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EPY51721.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EPY51721.1 - 0.23 10.2 4.6 0.72 8.6 0.0 2.9 3 1 1 4 4 4 0 DnaB-like helicase C terminal domain Pil1 PF13805.1 EPY51722.1 - 3.7e-102 341.1 0.2 5.3e-102 340.6 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 LTXXQ PF07813.7 EPY51722.1 - 0.87 10.0 3.9 0.41 11.1 0.1 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein Syja_N PF02383.13 EPY51723.1 - 4.8e-69 232.5 3.9 1.1e-67 228.1 1.7 2.2 2 0 0 2 2 2 2 SacI homology domain 6PF2K PF01591.13 EPY51724.1 - 2.2e-38 131.5 4.9 2.3e-37 128.2 3.4 2.0 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPY51724.1 - 3.9e-27 95.2 0.0 6.4e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EPY51724.1 - 0.0027 18.4 1.5 0.06 14.1 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EPY51724.1 - 0.0045 16.8 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPY51724.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF4325 PF14213.1 EPY51724.1 - 0.15 11.7 0.4 13 5.5 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4325) ATP-synt_C PF00137.16 EPY51725.1 - 8.8e-31 105.6 26.9 5.1e-18 64.7 4.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CLN3 PF02487.12 EPY51727.1 - 3.3e-77 259.9 34.0 1.6e-72 244.5 17.8 2.1 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 EPY51727.1 - 0.0066 15.2 37.8 0.013 14.2 25.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF726 PF05277.7 EPY51728.1 - 4.6e-115 384.1 0.8 5.8e-115 383.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_1 PF00561.15 EPY51728.1 - 0.041 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPY51728.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2636 PF11120.3 EPY51729.1 - 0.12 11.8 0.9 0.2 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) PIG-P PF08510.7 EPY51729.1 - 0.13 11.8 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 PIG-P Metallopep PF12044.3 EPY51730.1 - 1.6e-138 461.7 0.0 1.9e-138 461.4 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EPY51730.1 - 0.0051 16.7 1.1 0.45 10.4 0.3 2.6 1 1 1 2 2 2 1 Jacalin-like lectin domain Reprolysin_2 PF13574.1 EPY51730.1 - 0.024 14.7 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EPY51730.1 - 0.034 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 MreC PF04085.9 EPY51730.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 rod shape-determining protein MreC Reprolysin_4 PF13583.1 EPY51730.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PCI PF01399.22 EPY51731.1 - 8.1e-13 48.6 2.6 3.8e-12 46.4 0.0 3.0 3 1 0 3 3 3 1 PCI domain MiaE_2 PF13794.1 EPY51731.1 - 0.064 12.7 0.1 0.99 8.8 0.0 2.2 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like IPK PF03770.11 EPY51732.1 - 1.6e-45 155.1 0.0 2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_L7Ae PF01248.21 EPY51733.1 - 7.2e-26 89.5 0.0 8.8e-26 89.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EPY51733.1 - 0.0019 18.0 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Calreticulin PF00262.13 EPY51734.1 - 2.4e-151 503.5 1.0 2.4e-151 503.5 0.7 1.4 2 0 0 2 2 2 1 Calreticulin family Peroxin-13_N PF04088.8 EPY51735.1 - 2.8e-28 98.8 0.6 4.7e-28 98.1 0.4 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EPY51735.1 - 8.8e-14 50.7 0.1 1.4e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPY51735.1 - 5.3e-13 48.3 0.1 8.2e-13 47.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPY51735.1 - 2.1e-12 46.2 0.1 3.5e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SET PF00856.23 EPY51736.1 - 1e-11 45.4 0.3 8.5e-11 42.4 0.2 2.1 1 1 0 1 1 1 1 SET domain Phage_int_SAM_1 PF02899.12 EPY51736.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Pyrophosphatase PF00719.14 EPY51736.1 - 0.045 13.1 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Inorganic pyrophosphatase TFIIS_M PF07500.9 EPY51737.1 - 3.4e-29 101.2 2.0 3.4e-29 101.2 1.4 2.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EPY51737.1 - 4.2e-18 64.6 8.3 7e-18 63.9 5.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EPY51737.1 - 1.2e-12 47.0 0.3 2.3e-12 46.1 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.8 EPY51737.1 - 0.066 12.9 2.2 0.12 12.1 1.5 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ResIII PF04851.10 EPY51738.1 - 7.9e-23 81.2 0.0 2.5e-22 79.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPY51738.1 - 7e-19 67.9 0.0 8.9e-18 64.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY51738.1 - 2.4e-18 65.7 0.1 6.2e-18 64.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPY51738.1 - 0.0035 17.4 0.1 0.024 14.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain Aldolase_II PF00596.16 EPY51739.1 - 7e-38 130.0 0.0 8.3e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1604 PF07713.8 EPY51740.1 - 6.2e-32 109.2 1.7 6.2e-32 109.2 1.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) Zip PF02535.17 EPY51740.1 - 0.055 12.4 0.1 0.083 11.8 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter G-patch_2 PF12656.2 EPY51740.1 - 0.11 12.3 0.3 3.9 7.3 0.1 2.6 1 1 1 2 2 2 0 DExH-box splicing factor binding site Rad51 PF08423.6 EPY51741.1 - 3.3e-24 85.1 0.0 1.4e-23 83.1 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPY51741.1 - 2.2e-09 36.9 0.0 5.2e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EPY51741.1 - 5.2e-07 29.0 0.0 9.6e-07 28.1 0.0 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.16 EPY51741.1 - 7.3e-06 25.2 0.0 0.0024 16.9 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ABC_tran PF00005.22 EPY51741.1 - 0.0066 16.7 0.1 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EPY51741.1 - 0.01 15.9 0.3 0.041 14.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPY51741.1 - 0.062 13.4 0.0 0.29 11.3 0.0 2.2 1 1 0 1 1 1 0 RNA helicase PAXNEB PF05625.6 EPY51741.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein AAA_18 PF13238.1 EPY51741.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY51741.1 - 0.13 12.1 0.1 0.25 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain HA2 PF04408.18 EPY51743.1 - 9.6e-17 60.8 0.0 2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPY51743.1 - 3.7e-12 45.9 0.0 1.1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPY51743.1 - 2.3e-11 43.5 0.0 5.3e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EPY51743.1 - 8.4e-06 25.9 0.2 1.7e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EPY51743.1 - 5.4e-05 22.7 0.1 9e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EPY51743.1 - 0.00019 21.3 0.8 0.011 15.5 0.6 2.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPY51743.1 - 0.0019 17.1 0.1 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Flavi_DEAD PF07652.9 EPY51743.1 - 0.0033 17.2 0.1 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain Arch_ATPase PF01637.13 EPY51743.1 - 0.0044 16.7 0.1 0.0098 15.6 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase ResIII PF04851.10 EPY51743.1 - 0.043 13.6 1.2 5.1 6.8 0.1 2.9 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EPY51743.1 - 0.046 14.0 0.1 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EPY51743.1 - 0.19 12.0 3.1 0.68 10.2 2.2 2.0 1 1 0 1 1 1 0 AAA domain Ufd2P_core PF10408.4 EPY51744.1 - 4.9e-181 603.1 20.1 4.9e-181 603.1 13.9 1.9 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 EPY51744.1 - 3.7e-27 94.0 1.7 7.5e-27 93.1 0.3 2.3 2 0 0 2 2 2 1 U-box domain OGFr_N PF04664.8 EPY51744.1 - 0.004 16.4 0.7 0.074 12.3 0.2 2.8 3 0 0 3 3 3 1 Opioid growth factor receptor (OGFr) conserved region Ras PF00071.17 EPY51745.1 - 3e-56 189.2 0.0 3.6e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY51745.1 - 1.6e-15 57.6 0.0 2.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY51745.1 - 2.2e-05 23.7 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPY51745.1 - 0.032 13.4 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPY51745.1 - 0.055 12.6 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ICE2 PF08426.5 EPY51746.1 - 3.6e-101 338.7 32.8 4.4e-101 338.4 22.7 1.1 1 0 0 1 1 1 1 ICE2 Ribosom_S12_S23 PF00164.20 EPY51747.1 - 7.5e-40 135.1 0.5 8.9e-40 134.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mpp10 PF04006.7 EPY51748.1 - 9.3e-146 486.6 64.7 1.2e-145 486.3 44.8 1.0 1 0 0 1 1 1 1 Mpp10 protein PNK3P PF08645.6 EPY51749.1 - 4.4e-52 175.7 0.0 9.8e-52 174.5 0.0 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EPY51749.1 - 2.9e-23 82.3 0.0 1.4e-22 80.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPY51749.1 - 2.4e-07 30.0 0.1 0.0017 17.5 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 EPY51749.1 - 0.00054 19.2 2.1 0.41 9.8 0.2 2.2 1 1 0 2 2 2 2 Chromatin associated protein KTI12 HAD_2 PF13419.1 EPY51749.1 - 0.0018 18.4 0.1 0.39 10.9 0.0 2.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_18 PF13238.1 EPY51749.1 - 0.0034 17.6 0.1 0.3 11.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EPY51749.1 - 0.0045 17.7 0.5 0.2 12.4 0.1 2.8 3 0 0 3 3 3 1 AAA domain Hydrolase_6 PF13344.1 EPY51749.1 - 0.019 14.8 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase 6PF2K PF01591.13 EPY51749.1 - 0.022 13.8 0.2 0.84 8.6 0.0 2.2 1 1 1 2 2 2 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.18 EPY51749.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3046 PF11248.3 EPY51749.1 - 0.031 14.2 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) AAA_22 PF13401.1 EPY51749.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPY51749.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EPY51749.1 - 0.085 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EPY51749.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPY51749.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pyrophosphatase PF00719.14 EPY51750.1 - 1.2e-51 174.2 0.1 1.6e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF2417 PF10329.4 EPY51751.1 - 1.7e-48 165.1 7.9 2.3e-48 164.6 5.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EPY51751.1 - 1.7e-11 44.4 0.0 2.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY51751.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY51751.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CBFD_NFYB_HMF PF00808.18 EPY51752.1 - 1.7e-28 98.4 0.5 2.6e-28 97.8 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPY51752.1 - 1.8e-08 34.3 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EPY51752.1 - 0.0014 18.3 0.1 0.0018 18.0 0.0 1.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EPY51752.1 - 0.0026 17.4 0.1 0.0073 16.0 0.0 1.7 1 1 0 1 1 1 1 Bromodomain associated PAN_3 PF08277.7 EPY51752.1 - 0.016 14.8 0.2 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain TFIID_20kDa PF03847.8 EPY51752.1 - 0.028 14.6 0.4 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EPY51752.1 - 0.057 13.6 0.6 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Kinetochore component CENP-S tRNA-synt_2c PF01411.14 EPY51753.1 - 6.9e-219 727.7 0.0 1.1e-218 727.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EPY51753.1 - 3e-17 62.2 0.1 7e-17 61.0 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EPY51753.1 - 7.4e-09 35.1 0.0 2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 DHHA1 domain Dynactin_p22 PF07426.6 EPY51753.1 - 0.0064 15.8 0.6 0.014 14.7 0.4 1.5 1 0 0 1 1 1 1 Dynactin subunit p22 Prok-TraM PF09228.5 EPY51753.1 - 0.036 14.1 0.4 0.26 11.4 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM HVSL PF09749.4 EPY51754.1 - 1.7e-41 141.7 2.4 2.1e-41 141.5 1.7 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pkinase PF00069.20 EPY51755.1 - 8.2e-58 195.5 0.0 9.5e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51755.1 - 1.4e-20 73.4 0.0 2.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY51755.1 - 1.5e-06 28.1 0.1 4.9e-05 23.1 0.2 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPY51755.1 - 0.014 14.2 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EPY51755.1 - 0.026 14.0 0.1 0.056 13.0 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EPY51755.1 - 0.059 12.6 0.1 7.4 5.8 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL P53_tetramer PF07710.6 EPY51755.1 - 0.093 11.8 0.0 4.9 6.3 0.0 2.5 2 0 0 2 2 2 0 P53 tetramerisation motif APC_CDC26 PF10471.4 EPY51756.1 - 6.4e-09 36.4 0.9 1.4e-08 35.3 0.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 MannoseP_isomer PF01050.13 EPY51756.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Pribosyltran PF00156.22 EPY51757.1 - 3.1e-08 33.3 0.3 5.9e-07 29.2 0.2 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Cation_efflux PF01545.16 EPY51758.1 - 2.3e-75 253.3 5.0 2.6e-75 253.1 3.5 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EPY51758.1 - 0.0013 17.8 0.4 0.0021 17.1 0.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Sin3_corepress PF08295.7 EPY51759.1 - 2.5e-36 123.4 2.5 4.5e-35 119.4 0.0 2.9 3 0 0 3 3 3 1 Sin3 family co-repressor PAH PF02671.16 EPY51759.1 - 5.3e-19 67.5 11.6 1.4e-06 27.8 0.2 4.2 4 0 0 4 4 4 3 Paired amphipathic helix repeat Pkinase PF00069.20 EPY51760.1 - 2.1e-72 243.4 0.0 3.8e-72 242.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51760.1 - 6.7e-42 143.3 0.0 1.7e-41 142.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EPY51760.1 - 1.3e-33 114.7 1.8 3.9e-18 65.1 0.4 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EPY51760.1 - 3.5e-07 29.4 0.0 5.1e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPY51760.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPY51760.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LETM1 PF07766.8 EPY51761.1 - 1.9e-94 315.6 0.1 2.7e-94 315.1 0.1 1.2 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EPY51761.1 - 0.03 13.8 0.0 7 6.2 0.0 2.9 2 1 0 2 2 2 0 SAP domain MutS_V PF00488.16 EPY51762.1 - 4.7e-88 294.5 0.1 9e-88 293.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPY51762.1 - 1.6e-42 145.6 0.0 3.9e-42 144.3 0.0 1.7 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPY51762.1 - 7.4e-19 67.8 0.0 1.9e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EPY51762.1 - 4.8e-11 42.8 0.2 1.9e-09 37.7 0.0 3.4 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EPY51762.1 - 3.9e-05 23.7 2.8 0.0002 21.4 0.7 3.2 3 0 0 3 3 3 1 MutS family domain IV AAA_29 PF13555.1 EPY51762.1 - 0.033 13.6 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Prp19 PF08606.6 EPY51762.1 - 0.053 13.2 0.6 0.22 11.2 0.1 2.3 1 1 1 2 2 2 0 Prp19/Pso4-like AAA_23 PF13476.1 EPY51762.1 - 3.5 7.9 14.5 0.71 10.1 0.0 3.3 2 1 0 2 2 2 0 AAA domain TAFII55_N PF04658.8 EPY51763.1 - 5.7e-57 191.7 0.2 5.7e-57 191.7 0.1 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region Nucleoplasmin PF03066.10 EPY51763.1 - 0.31 10.5 8.4 0.61 9.6 5.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EPY51763.1 - 0.75 8.9 6.9 1.4 8.0 4.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EPY51763.1 - 1.5 9.1 11.6 4.1 7.6 8.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EPY51763.1 - 6.1 4.7 12.0 10 4.0 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Fe-ADH PF00465.14 EPY51764.1 - 2.1e-51 174.7 0.1 2.7e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPY51764.1 - 1.7e-38 132.3 0.3 2.1e-38 132.0 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EPY51764.1 - 4.2e-06 25.8 1.1 2.5e-05 23.3 0.8 1.9 1 1 0 1 1 1 1 3-dehydroquinate synthase DUF605 PF04652.11 EPY51765.1 - 7.6e-50 170.3 1.5 9.8e-50 170.0 1.1 1.2 1 0 0 1 1 1 1 Vta1 like DUF4404 PF14357.1 EPY51765.1 - 0.077 13.4 2.6 0.27 11.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Thioredoxin PF00085.15 EPY51766.1 - 1.3e-21 76.2 0.0 3.3e-19 68.4 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EPY51766.1 - 7.1e-08 32.6 0.1 5.9e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPY51766.1 - 8.8e-05 22.5 1.2 0.0009 19.3 0.0 2.9 3 2 0 3 3 3 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EPY51766.1 - 0.00037 20.3 1.6 0.0032 17.3 0.1 2.5 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EPY51766.1 - 0.0009 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EPY51766.1 - 0.0013 18.4 0.1 0.0043 16.7 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EPY51766.1 - 0.0016 18.0 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Redoxin DUF3594 PF12165.3 EPY51766.1 - 0.0028 17.2 0.3 0.23 11.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3594) Thioredoxin_7 PF13899.1 EPY51766.1 - 0.0032 17.4 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EPY51766.1 - 0.023 14.1 0.5 1.3 8.4 0.0 2.9 3 1 0 3 3 3 0 F plasmid transfer operon protein Sec10 PF07393.6 EPY51767.1 - 9.1e-150 500.1 5.1 1.3e-149 499.6 3.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Exonuc_VII_S PF02609.11 EPY51767.1 - 0.055 13.2 0.3 0.2 11.4 0.2 2.0 1 0 0 1 1 1 0 Exonuclease VII small subunit zf-PARP PF00645.13 EPY51768.1 - 2.3e-16 59.8 0.0 3.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FAD_binding_1 PF00667.15 EPY51769.1 - 1e-37 129.7 0.0 1.6e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPY51769.1 - 2.1e-14 53.9 0.0 3.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HTH_8 PF02954.14 EPY51769.1 - 0.27 10.8 0.8 0.86 9.2 0.2 2.0 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family Acyltransferase PF01553.16 EPY51770.1 - 7.9e-08 31.8 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase FTA2 PF13095.1 EPY51771.1 - 5.6e-09 35.8 0.1 7.9e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF3785 PF12653.2 EPY51771.1 - 0.01 15.7 0.1 0.025 14.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) DUF1465 PF07323.7 EPY51771.1 - 0.056 13.0 0.5 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) FlxA PF14282.1 EPY51771.1 - 0.6 10.0 10.8 0.12 12.3 4.7 2.0 2 1 0 2 2 2 0 FlxA-like protein SIR2 PF02146.12 EPY51772.1 - 2e-24 86.2 0.0 6.3e-24 84.6 0.0 1.8 1 1 0 1 1 1 1 Sir2 family UvrD_C PF13361.1 EPY51772.1 - 0.038 13.4 0.0 0.081 12.3 0.0 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain zf-UDP PF14569.1 EPY51772.1 - 0.052 13.3 0.2 0.14 11.9 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.5 EPY51772.1 - 0.12 12.3 0.9 0.32 10.9 0.7 1.8 1 0 0 1 1 1 0 Zinc ribbon domain SNF2_N PF00176.18 EPY51773.1 - 4.2e-73 245.7 0.4 4.2e-73 245.7 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EPY51773.1 - 3.9e-23 80.8 1.6 1.7e-11 43.5 0.1 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EPY51773.1 - 1.5e-15 56.7 0.0 4.4e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY51773.1 - 0.00017 21.1 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase CHDCT2 PF08074.6 EPY51773.1 - 0.0037 17.0 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain FtsK_SpoIIIE PF01580.13 EPY51773.1 - 1.8 7.9 6.9 4.6 6.6 4.6 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family APG12 PF04110.8 EPY51774.1 - 6.9e-14 51.8 0.1 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG12 PF04110.8 EPY51775.1 - 1.4e-33 114.9 0.0 2.3e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EPY51775.1 - 0.00011 22.1 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like PAP1 PF08601.5 EPY51776.1 - 4.2e-31 108.9 45.3 2e-27 96.8 11.5 4.3 1 1 2 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 EPY51776.1 - 1.3e-07 31.4 10.0 1.3e-07 31.4 6.9 2.0 2 0 0 2 2 2 1 bZIP transcription factor MAD PF05557.8 EPY51776.1 - 0.00039 18.6 2.5 0.00057 18.1 1.7 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein CCDC155 PF14662.1 EPY51776.1 - 0.012 15.2 4.7 0.022 14.3 3.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Vac_Fusion PF02346.11 EPY51776.1 - 0.05 13.0 1.0 0.33 10.4 0.3 2.2 2 0 0 2 2 2 0 Chordopoxvirus fusion protein WD40_alt PF14077.1 EPY51776.1 - 0.1 12.2 0.7 0.27 10.9 0.5 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif Adeno_PIX PF03955.9 EPY51776.1 - 0.13 12.7 4.8 0.056 13.9 1.3 1.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TMPIT PF07851.8 EPY51776.1 - 0.18 10.8 2.0 0.29 10.1 1.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein bZIP_2 PF07716.10 EPY51776.1 - 0.25 11.1 12.5 1.2 9.0 8.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper IncA PF04156.9 EPY51776.1 - 0.33 10.5 4.3 0.62 9.6 3.0 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EPY51776.1 - 5.7 6.4 6.1 1.4 8.4 1.4 2.0 1 1 1 2 2 2 0 Septum formation initiator Ribosomal_L15e PF00827.12 EPY51778.1 - 5.5e-89 296.7 9.2 6.7e-89 296.4 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Fungal_trans PF04082.13 EPY51779.1 - 3e-27 95.1 0.1 6.7e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY51779.1 - 5.6e-09 35.7 13.7 5.6e-09 35.7 9.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tox-GHH2 PF15635.1 EPY51779.1 - 0.74 10.2 12.3 0.067 13.5 3.8 2.3 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Fungal_trans PF04082.13 EPY51780.1 - 3.1e-27 95.0 0.1 6.9e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY51780.1 - 5.7e-09 35.7 13.7 5.7e-09 35.7 9.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tox-GHH2 PF15635.1 EPY51780.1 - 0.77 10.1 12.3 0.069 13.5 3.8 2.3 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 Chalcone PF02431.10 EPY51781.1 - 1e-36 126.1 0.1 1.4e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase HAUS6_N PF14661.1 EPY51781.1 - 0.073 12.4 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Chromo PF00385.19 EPY51782.1 - 1.7e-14 53.1 0.5 6.1e-14 51.4 0.4 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.17 EPY51782.1 - 4.1e-05 23.1 0.1 9.6e-05 21.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51782.1 - 0.0003 20.6 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 EPY51783.1 - 1.7e-63 212.8 0.8 2e-63 212.5 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY51783.1 - 4e-20 72.4 0.1 6.6e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY51783.1 - 9.7e-14 50.9 0.2 1.3e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPY51783.1 - 3.1e-06 27.1 0.1 4.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPY51783.1 - 4.4e-05 22.9 0.2 8.5e-05 22.0 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 EPY51783.1 - 0.00019 20.5 0.3 0.00021 20.4 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EPY51783.1 - 0.00027 20.1 0.3 0.00044 19.4 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPY51783.1 - 0.00051 20.1 0.1 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPY51783.1 - 0.0014 17.8 0.0 0.0035 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPY51783.1 - 0.026 14.8 0.3 0.039 14.2 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EPY51783.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EPY51783.1 - 0.038 13.8 0.1 0.075 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EPY51783.1 - 0.041 13.1 0.0 0.064 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3533 PF12051.3 EPY51783.1 - 0.051 12.3 0.4 0.056 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_5 PF07728.9 EPY51783.1 - 0.052 13.2 0.1 0.17 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EPY51783.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EPY51783.1 - 0.083 12.1 0.2 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 EPY51783.1 - 0.17 11.8 0.3 0.43 10.5 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain SHMT PF00464.14 EPY51784.1 - 5.5e-203 673.7 0.0 6.5e-203 673.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EPY51784.1 - 0.0038 16.4 0.0 0.0056 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EPY51784.1 - 0.027 13.4 0.0 0.062 12.2 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II DUF3554 PF12074.3 EPY51785.1 - 1.2e-42 146.5 13.6 1.2e-42 146.5 9.4 5.7 7 0 0 7 7 7 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EPY51785.1 - 3.4e-42 138.7 25.9 0.00077 19.3 0.0 19.9 20 0 0 20 20 20 11 HEAT repeat HEAT_2 PF13646.1 EPY51785.1 - 1.5e-38 130.9 32.6 2.1e-08 34.3 0.0 13.9 7 3 7 14 14 14 11 HEAT repeats HEAT_EZ PF13513.1 EPY51785.1 - 5.5e-31 106.2 36.6 0.0002 21.7 0.0 18.1 15 3 4 19 19 19 11 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPY51785.1 - 5.1e-13 49.2 0.4 0.24 11.7 0.0 8.4 7 2 0 8 8 8 4 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 EPY51785.1 - 2.5e-07 30.5 4.2 0.65 10.0 0.0 7.6 7 0 0 7 7 7 1 HEAT repeat associated with sister chromatid cohesion Utp11 PF03998.8 EPY51786.1 - 2.5e-68 230.5 29.4 2.8e-68 230.3 20.4 1.0 1 0 0 1 1 1 1 Utp11 protein DUF1365 PF07103.6 EPY51786.1 - 0.3 10.0 4.7 0.064 12.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1365) DRY_EERY PF09750.4 EPY51786.1 - 1.6 8.8 7.6 4.7 7.3 0.1 2.7 2 1 1 3 3 3 0 Alternative splicing regulator EMG1 PF03587.9 EPY51787.1 - 5.1e-78 261.0 0.0 7.8e-78 260.4 0.0 1.3 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PNRC PF15365.1 EPY51788.1 - 0.00014 21.7 4.9 0.00014 21.7 3.4 3.2 1 1 1 3 3 3 2 Proline-rich nuclear receptor coactivator MSC PF09402.5 EPY51789.1 - 9.6e-82 274.3 1.2 1.4e-81 273.7 0.8 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EPY51789.1 - 8.2e-10 38.0 0.0 1.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Armet PF10208.4 EPY51789.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding RRN3 PF05327.6 EPY51790.1 - 2.6e-153 511.1 5.7 3.8e-153 510.6 4.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 YniB PF14002.1 EPY51790.1 - 0.094 12.1 1.3 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 YniB-like protein Ribosomal_S7e PF01251.13 EPY51793.1 - 3.1e-81 271.4 0.4 3.5e-81 271.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e EB1 PF03271.12 EPY51794.1 - 2.8e-17 62.4 0.2 5.4e-17 61.5 0.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EPY51794.1 - 2.7e-07 30.5 0.9 4.1e-06 26.7 0.4 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EPY51794.1 - 0.035 12.2 0.1 0.046 11.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like F-box-like_2 PF13013.1 EPY51795.1 - 7.2e-20 70.7 0.1 1.9e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like domain UCR_6-4kD PF08997.5 EPY51795.1 - 0.12 12.1 0.2 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein zf-CCHC PF00098.18 EPY51796.1 - 7e-49 161.5 53.3 8.8e-08 31.7 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EPY51796.1 - 4.9e-15 54.9 42.5 0.003 17.1 0.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EPY51796.1 - 6.6e-06 25.7 50.3 0.15 11.8 3.3 7.0 1 1 6 7 7 7 5 Zinc knuckle zf-CCHC_6 PF15288.1 EPY51796.1 - 0.0011 18.5 45.1 0.31 10.7 0.7 6.8 6 1 1 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 EPY51796.1 - 0.066 12.7 0.6 0.066 12.7 0.4 6.6 4 2 3 7 7 7 0 Zinc knuckle zf-CCHC_5 PF14787.1 EPY51796.1 - 7.7 6.0 42.0 0.065 12.7 1.4 6.9 5 2 2 7 7 7 0 GAG-polyprotein viral zinc-finger Methyltransf_11 PF08241.7 EPY51797.1 - 5.3e-13 49.2 0.0 8.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY51797.1 - 1.8e-07 31.0 0.1 3.5e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY51797.1 - 9.3e-06 25.3 0.0 1.7e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY51797.1 - 0.00015 22.0 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY51797.1 - 0.0011 19.3 0.2 0.0083 16.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY51797.1 - 0.072 13.6 0.3 0.42 11.2 0.2 2.1 1 1 0 1 1 1 0 Methyltransferase domain BTB PF00651.26 EPY51798.1 - 2.3e-25 88.7 1.8 8.7e-14 51.4 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EPY51798.1 - 4.9e-09 35.5 0.0 1.4e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EPY51798.1 - 1.2e-08 35.1 0.0 3.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPY51798.1 - 1.5e-08 34.8 0.0 1.1e-07 32.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPY51798.1 - 5.4e-06 26.1 0.6 0.0052 16.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EPY51798.1 - 1e-05 25.6 0.0 0.00086 19.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BACK PF07707.10 EPY51798.1 - 7e-05 22.6 0.1 0.00032 20.4 0.0 2.2 1 0 0 1 1 1 1 BTB And C-terminal Kelch CAP_GLY PF01302.20 EPY51799.1 - 2.5e-24 84.7 0.2 3.7e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EPY51799.1 - 6.3e-12 45.5 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EPY51799.1 - 0.065 12.6 0.3 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family RNase_HII PF01351.13 EPY51800.1 - 2e-62 210.3 0.0 2.6e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII ADK PF00406.17 EPY51801.1 - 3.7e-60 202.1 0.0 4.5e-60 201.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EPY51801.1 - 1e-14 53.8 0.1 3.3e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EPY51801.1 - 4.1e-07 30.8 0.0 6.6e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY51801.1 - 6.3e-07 29.3 0.0 2.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPY51801.1 - 0.00054 20.2 0.4 0.0021 18.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPY51801.1 - 0.0035 16.4 0.4 0.005 15.9 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin CTD_bind PF04818.8 EPY51802.1 - 0.0047 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EPY51802.1 - 0.0067 16.0 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf-C2H2_4 PF13894.1 EPY51802.1 - 0.083 13.2 4.2 6.8 7.2 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1460 PF07313.7 EPY51802.1 - 0.084 12.0 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) zf-C2HC_2 PF13913.1 EPY51802.1 - 1.4 8.6 9.8 8.4 6.1 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type PUF PF00806.14 EPY51803.1 - 1.8e-40 134.1 12.5 2.6e-06 26.5 0.1 8.5 9 0 0 9 9 9 6 Pumilio-family RNA binding repeat Bcl-2 PF00452.14 EPY51803.1 - 0.0073 16.4 2.6 0.14 12.2 0.3 3.5 2 1 2 4 4 4 1 Apoptosis regulator proteins, Bcl-2 family Trns_repr_metal PF02583.12 EPY51803.1 - 1.3 9.2 5.5 0.68 10.1 0.2 3.0 4 0 0 4 4 4 0 Metal-sensitive transcriptional repressor CHZ PF09649.5 EPY51804.1 - 3.9e-11 41.9 1.4 3.9e-11 41.9 1.0 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ HHV6-IE PF03753.8 EPY51804.1 - 0.66 7.3 5.4 0.72 7.2 3.7 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein UPF0300 PF08594.5 EPY51805.1 - 1.2e-69 233.5 0.7 1.2e-69 233.5 0.5 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0300) RNA_pol_Rpb2_6 PF00562.23 EPY51806.1 - 5.7e-121 403.9 0.0 9.8e-121 403.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPY51806.1 - 1.9e-63 213.0 0.2 1.6e-62 210.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPY51806.1 - 1.6e-39 135.3 0.1 5.8e-39 133.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EPY51806.1 - 9.5e-30 102.7 0.1 2.8e-29 101.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EPY51806.1 - 3e-26 91.0 0.3 1.1e-25 89.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EPY51806.1 - 9.8e-20 70.0 0.1 2.1e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EPY51806.1 - 5e-14 52.0 1.9 1.4e-13 50.5 1.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EPY51806.1 - 0.016 13.6 0.0 0.028 12.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus Y142 protein DUF619 PF04768.8 EPY51807.1 - 2e-35 121.6 0.0 6.3e-35 120.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EPY51807.1 - 3.2e-28 98.4 0.0 8e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EPY51807.1 - 3.1e-21 76.0 0.5 1.4e-20 73.8 0.2 2.2 3 0 0 3 3 3 1 Amino acid kinase family DapB_N PF01113.15 EPY51807.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EPY51807.1 - 0.037 14.5 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold OTCace PF00185.19 EPY51808.1 - 3.1e-45 153.8 0.7 4.2e-45 153.4 0.1 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EPY51808.1 - 2.9e-44 150.1 0.0 4.3e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain HMG_box_2 PF09011.5 EPY51809.1 - 1.3e-08 35.0 0.1 1.3e-08 35.0 0.1 2.5 2 1 0 2 2 2 1 HMG-box domain HMG_box PF00505.14 EPY51809.1 - 8.5e-08 32.3 9.4 1.8e-07 31.2 1.3 3.0 2 1 0 2 2 2 1 HMG (high mobility group) box DnaJ PF00226.26 EPY51809.1 - 0.027 14.1 0.9 0.73 9.6 0.1 3.3 3 1 0 3 3 3 0 DnaJ domain DUF2203 PF09969.4 EPY51809.1 - 0.048 13.8 1.7 4.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FAM195 PF14799.1 EPY51809.1 - 0.054 13.3 0.9 1 9.2 0.1 2.3 2 0 0 2 2 2 0 FAM195 family DUF1104 PF06518.6 EPY51809.1 - 0.21 11.7 7.5 0.23 11.6 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1104) Enkurin PF13864.1 EPY51809.1 - 0.28 11.4 6.2 1.6 9.0 0.2 2.3 2 0 0 2 2 2 0 Calmodulin-binding DUF3106 PF11304.3 EPY51809.1 - 0.3 11.5 9.2 3.3 8.1 2.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) YlqD PF11068.3 EPY51809.1 - 1.3 9.0 5.0 1.2 9.1 1.1 2.2 2 0 0 2 2 2 0 YlqD protein DUF3552 PF12072.3 EPY51809.1 - 4.9 6.2 9.6 0.99 8.5 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) OmpH PF03938.9 EPY51809.1 - 7 6.5 8.3 7.4 6.4 1.9 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Vps26 PF03643.10 EPY51810.1 - 2.9e-129 429.7 5.0 3.3e-129 429.5 3.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EPY51810.1 - 0.0059 16.4 4.2 0.064 13.0 0.3 3.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain AAA_17 PF13207.1 EPY51811.1 - 6.5e-12 46.3 0.0 1.2e-11 45.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY51811.1 - 7.6e-12 45.3 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EPY51811.1 - 4.9e-11 42.7 0.0 8.9e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 EPY51811.1 - 2.4e-10 40.8 0.1 1.3e-09 38.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPY51811.1 - 4.1e-05 23.7 0.0 7.6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EPY51811.1 - 0.00031 20.4 0.0 0.0004 20.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_24 PF13479.1 EPY51811.1 - 0.00032 20.3 0.1 0.00064 19.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPY51811.1 - 0.00039 20.7 0.0 0.00092 19.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 EPY51811.1 - 0.00055 20.1 0.0 0.00096 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 EPY51811.1 - 0.00078 18.8 0.2 0.43 9.9 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Rad17 PF03215.10 EPY51811.1 - 0.0011 17.7 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Cytidylate_kin2 PF13189.1 EPY51811.1 - 0.0011 18.8 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_14 PF13173.1 EPY51811.1 - 0.0022 17.8 0.0 0.0083 16.0 0.0 1.9 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EPY51811.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPY51811.1 - 0.004 16.6 0.1 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain PhoH PF02562.11 EPY51811.1 - 0.004 16.4 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein RNA_helicase PF00910.17 EPY51811.1 - 0.0049 17.0 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_23 PF13476.1 EPY51811.1 - 0.005 17.1 0.1 0.011 16.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPY51811.1 - 0.0063 15.6 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EPY51811.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 EPY51811.1 - 0.0085 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 EPY51811.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EPY51811.1 - 0.015 14.2 0.0 0.058 12.2 0.0 1.8 2 1 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 EPY51811.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EPY51811.1 - 0.016 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain IPT PF01745.11 EPY51811.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.4 2 0 0 2 2 1 0 Isopentenyl transferase ADK PF00406.17 EPY51811.1 - 0.019 14.8 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Adenylate kinase AAA_28 PF13521.1 EPY51811.1 - 0.029 14.3 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPY51811.1 - 0.035 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EPY51811.1 - 0.036 13.7 0.0 0.087 12.5 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 EPY51811.1 - 0.051 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EPY51811.1 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EPY51811.1 - 0.073 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EPY51811.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EPY51811.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 EPY51811.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EPY51811.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 NTPase Mpv17_PMP22 PF04117.7 EPY51812.1 - 8.1e-25 86.2 3.2 1.4e-24 85.4 2.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family RDD PF06271.7 EPY51812.1 - 5 7.0 8.8 1.1 9.2 2.7 2.1 2 0 0 2 2 2 0 RDD family adh_short PF00106.20 EPY51813.1 - 1.7e-24 86.5 0.0 2.4e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY51813.1 - 2e-08 34.2 0.1 3.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY51813.1 - 1e-07 31.7 0.0 2e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY51813.1 - 3.4e-05 23.9 0.1 5.8e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY51813.1 - 0.00033 20.1 0.1 0.00056 19.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPY51813.1 - 0.0062 15.4 0.6 0.0083 15.0 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EPY51813.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EPY51813.1 - 0.016 15.3 0.4 0.056 13.5 0.2 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EPY51813.1 - 0.038 13.4 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EPY51813.1 - 0.044 12.7 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EPY51813.1 - 0.047 13.5 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4038 PF13204.1 EPY51813.1 - 0.073 12.3 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Ribosomal_L6 PF00347.18 EPY51814.1 - 1.2e-34 118.6 3.9 9.3e-20 70.9 0.2 2.0 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S5_C PF03719.10 EPY51815.1 - 1.7e-20 72.0 0.0 2.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EPY51815.1 - 5.3e-12 45.2 0.8 1.1e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DnaJ PF00226.26 EPY51816.1 - 4.4e-16 58.3 1.3 8.2e-16 57.4 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain ESSS PF10183.4 EPY51816.1 - 0.041 14.2 0.1 0.08 13.3 0.1 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COX14 PF14880.1 EPY51816.1 - 0.044 13.4 0.1 0.099 12.2 0.1 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Mito_carr PF00153.22 EPY51817.1 - 1.7e-66 219.9 4.5 5.1e-24 83.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.16 EPY51818.1 - 3.8e-28 96.7 11.2 4e-08 32.6 1.2 6.7 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EPY51818.1 - 8.7e-27 93.2 0.0 1e-10 41.5 0.0 5.3 2 2 3 5 5 5 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 EPY51818.1 - 2e-26 92.5 0.3 1.4e-08 35.0 0.0 5.1 3 1 3 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 EPY51818.1 - 9.7e-08 31.5 0.1 0.052 12.7 0.0 3.9 2 1 2 4 4 4 3 Pectic acid lyase Mago-bind PF09282.5 EPY51818.1 - 0.0014 18.0 0.0 0.33 10.5 0.0 2.8 2 0 0 2 2 2 1 Mago binding HSP70 PF00012.15 EPY51819.1 - 3.4e-270 897.1 7.0 3.9e-270 896.9 4.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPY51819.1 - 8e-18 64.1 0.2 1.9e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPY51819.1 - 0.00046 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EPY51819.1 - 0.0079 15.3 0.2 0.13 11.3 0.0 2.5 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase Ppx-GppA PF02541.11 EPY51819.1 - 0.034 13.3 0.6 0.065 12.4 0.0 1.6 2 0 0 2 2 2 0 Ppx/GppA phosphatase family TarH PF02203.10 EPY51819.1 - 0.21 11.4 3.4 0.4 10.4 2.3 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue Macoilin PF09726.4 EPY51819.1 - 2.2 6.4 8.5 6.5 4.9 4.3 1.9 1 1 0 2 2 2 0 Transmembrane protein Smg4_UPF3 PF03467.10 EPY51820.1 - 1.5e-27 96.7 0.2 1.5e-27 96.7 0.1 2.7 3 1 0 4 4 4 1 Smg-4/UPF3 family RRM_6 PF14259.1 EPY51820.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mitofilin PF09731.4 EPY51820.1 - 1.4 7.4 16.2 1.6 7.3 11.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1675 PF07897.6 EPY51820.1 - 9.7 5.9 14.6 14 5.4 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SUR7 PF06687.7 EPY51821.1 - 1.2e-16 60.9 15.0 1.9e-16 60.2 10.4 1.3 1 0 0 1 1 1 1 SUR7/PalI family Tetraspannin PF00335.15 EPY51821.1 - 0.063 12.5 5.9 0.11 11.7 4.1 1.4 1 0 0 1 1 1 0 Tetraspanin family MBOAT PF03062.14 EPY51822.1 - 3.7e-46 157.7 19.9 3.7e-46 157.7 13.8 2.1 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPY51822.1 - 4.1e-05 23.5 4.3 4.1e-05 23.5 3.0 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PAPS_reduct PF01507.14 EPY51823.1 - 4.5e-46 156.8 0.0 5.7e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF1043 PF06295.7 EPY51823.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Arb2 PF09757.4 EPY51824.1 - 7.9e-10 38.4 0.7 2e-09 37.1 0.5 1.5 1 1 0 1 1 1 1 Arb2 domain WD40 PF00400.27 EPY51825.1 - 2.8e-15 55.5 14.1 6.5e-05 22.6 0.0 4.9 5 1 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EPY51825.1 - 8.9e-05 20.8 0.3 0.00024 19.4 0.0 1.7 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY51825.1 - 0.00031 19.6 5.9 0.0042 15.9 0.4 3.7 1 1 2 3 3 3 1 Nup133 N terminal like Hira PF07569.6 EPY51825.1 - 0.028 13.6 0.1 0.63 9.2 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split PGA2 PF07543.7 EPY51826.1 - 3.3 7.5 9.6 3.4 7.4 6.0 1.6 1 1 1 2 2 2 0 Protein trafficking PGA2 Myb_DNA-binding PF00249.26 EPY51827.1 - 1.9e-18 66.2 0.4 3.9e-08 33.2 0.0 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY51827.1 - 5.3e-15 55.2 0.1 1.6e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Chorion_2 PF03964.10 EPY51827.1 - 0.014 15.8 3.6 0.032 14.7 2.5 1.6 1 0 0 1 1 1 0 Chorion family 2 Nt_Gln_amidase PF09764.4 EPY51827.1 - 0.049 12.9 0.1 0.097 11.9 0.1 1.4 1 0 0 1 1 1 0 N-terminal glutamine amidase MBA1 PF07961.6 EPY51828.1 - 1e-39 135.7 0.3 1.3e-39 135.3 0.2 1.0 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EPY51828.1 - 0.00046 20.1 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain Choline_kinase PF01633.15 EPY51829.1 - 2.2e-55 187.5 0.4 2.9e-55 187.1 0.3 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EPY51829.1 - 8.7e-09 35.4 0.0 2.8e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kin_N PF04428.9 EPY51829.1 - 7.7e-06 25.2 0.2 1.4e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Choline kinase N terminus RRM_1 PF00076.17 EPY51830.1 - 2.8e-24 84.5 0.1 6.7e-10 38.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51830.1 - 9.8e-22 76.5 0.1 6.5e-10 38.7 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51830.1 - 2e-18 66.0 0.0 3.8e-07 29.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EPY51830.1 - 0.0035 17.2 0.6 1.3 9.0 0.0 3.0 3 1 0 3 3 3 2 RNA binding domain RRM_3 PF08777.6 EPY51830.1 - 0.066 13.0 0.0 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif DUF2076 PF09849.4 EPY51831.1 - 4.1e-06 27.0 9.4 4.9e-06 26.7 6.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EPY51831.1 - 0.0013 18.5 5.7 0.0019 18.0 3.9 1.2 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EPY51831.1 - 0.06 13.4 1.0 0.087 12.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) COX17 PF05051.8 EPY51831.1 - 0.1 12.6 2.8 0.28 11.2 1.9 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Citrate_synt PF00285.16 EPY51832.1 - 1.7e-97 326.3 0.0 2.7e-97 325.7 0.0 1.3 2 0 0 2 2 2 1 Citrate synthase XH PF03469.9 EPY51832.1 - 0.093 12.3 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 XH domain E1-E2_ATPase PF00122.15 EPY51834.1 - 1.5e-20 73.2 0.0 3.4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPY51834.1 - 2.7e-13 50.8 0.0 1.8e-11 44.9 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPY51834.1 - 1.1e-10 42.0 0.0 2.4e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY51834.1 - 4.1e-07 29.8 0.0 1.4e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPY51834.1 - 0.00023 20.8 0.0 0.00049 19.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.1 EPY51834.1 - 0.035 12.8 0.3 0.076 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Ank_2 PF12796.2 EPY51836.1 - 4.7e-46 155.0 0.1 2.6e-18 66.1 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPY51836.1 - 7.1e-34 115.0 0.1 4.3e-09 36.3 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EPY51836.1 - 3.6e-32 108.5 0.0 3.5e-07 29.7 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EPY51836.1 - 1.1e-27 95.8 0.1 1.7e-10 41.1 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPY51836.1 - 1.6e-27 92.7 0.0 8.8e-06 25.4 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ribonuc_P_40 PF08584.6 EPY51837.1 - 4e-18 65.4 0.0 5.6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RNA_lig_T4_1 PF09511.5 EPY51838.1 - 3.6e-77 258.7 0.2 5.9e-77 258.0 0.2 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EPY51838.1 - 6.5e-52 176.2 0.2 1.3e-51 175.3 0.0 1.6 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EPY51838.1 - 1e-47 162.0 0.0 2.5e-47 160.8 0.0 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 EPY51838.1 - 0.00071 20.3 0.0 0.0028 18.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY51838.1 - 0.029 14.6 0.0 0.13 12.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain RolB_RolC PF02027.12 EPY51838.1 - 0.09 11.9 0.0 6.1 5.9 0.0 2.5 1 1 1 2 2 2 0 RolB/RolC glucosidase family IU_nuc_hydro PF01156.14 EPY51839.1 - 1.4e-95 320.1 3.0 1.6e-95 319.9 2.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CBFD_NFYB_HMF PF00808.18 EPY51840.1 - 9.9e-06 25.5 5.1 9.9e-06 25.5 3.5 2.6 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ycf1 PF05758.7 EPY51840.1 - 2 5.9 14.0 2.2 5.9 9.7 1.2 1 0 0 1 1 1 0 Ycf1 CBFD_NFYB_HMF PF00808.18 EPY51841.1 - 3.5e-07 30.1 0.0 4.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPY51841.1 - 0.0011 19.0 0.2 0.0019 18.2 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.1 EPY51841.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 Centromere kinetochore component W P16-Arc PF04699.9 EPY51842.1 - 4.8e-36 124.0 0.0 5.3e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Med20 PF08612.6 EPY51843.1 - 4e-20 71.9 0.0 5.3e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ILVD_EDD PF00920.16 EPY51844.1 - 1.8e-208 693.1 2.3 2.2e-208 692.9 1.6 1.0 1 0 0 1 1 1 1 Dehydratase family YEATS PF03366.11 EPY51845.1 - 2e-32 110.7 0.7 5e-32 109.4 0.5 1.7 1 0 0 1 1 1 1 YEATS family WVELL PF14043.1 EPY51845.1 - 0.034 13.7 0.1 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 WVELL protein DUF2968 PF11180.3 EPY51845.1 - 0.11 11.8 0.7 0.17 11.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HR1 PF02185.11 EPY51845.1 - 0.22 11.2 2.2 0.24 11.1 0.8 1.6 2 0 0 2 2 2 0 Hr1 repeat UPF0016 PF01169.14 EPY51846.1 - 2.6e-38 130.0 23.1 1.2e-21 76.6 3.2 2.4 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Nitrate_red_gam PF02665.9 EPY51846.1 - 0.3 10.4 4.0 0.13 11.6 0.3 2.0 2 0 0 2 2 2 0 Nitrate reductase gamma subunit DUF204 PF02659.10 EPY51846.1 - 4.8 7.3 12.8 0.36 10.9 2.6 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF FHA PF00498.21 EPY51847.1 - 1.3e-17 63.6 0.0 2e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EPY51847.1 - 1.8e-05 24.4 14.6 4.7e-05 23.1 9.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EPY51847.1 - 0.00073 19.6 6.6 0.0012 18.9 2.5 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPY51847.1 - 0.027 14.3 4.4 0.077 12.8 3.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EPY51847.1 - 0.06 13.0 11.9 0.17 11.6 8.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EPY51847.1 - 0.46 10.2 10.4 0.53 10.0 5.9 2.1 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_2 PF13923.1 EPY51847.1 - 1.3 9.0 15.0 4.4 7.4 10.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY51847.1 - 1.5 8.5 15.2 1.5 8.5 9.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) COMPASS-Shg1 PF05205.7 EPY51848.1 - 4.7e-20 71.8 0.9 6e-20 71.5 0.6 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Clathrin PF00637.15 EPY51848.1 - 0.076 12.6 0.1 0.099 12.2 0.1 1.4 1 1 0 1 1 1 0 Region in Clathrin and VPS TcdB_N PF12918.2 EPY51848.1 - 0.16 12.0 2.0 0.17 11.9 0.5 1.7 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Gly_transf_sug PF04488.10 EPY51849.1 - 7.8e-25 87.2 0.1 1.4e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPY51849.1 - 6.2e-05 21.6 2.4 0.011 14.3 0.1 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain MOZ_SAS PF01853.13 EPY51850.1 - 3.1e-83 277.6 1.1 4.4e-83 277.1 0.8 1.2 1 0 0 1 1 1 1 MOZ/SAS family HTH_15 PF12324.3 EPY51850.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase He_PIG_assoc PF10632.4 EPY51850.1 - 0.09 12.1 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Sec3_C_2 PF15278.1 EPY51851.1 - 7.2e-22 77.3 5.2 1.7e-21 76.1 3.6 1.7 1 0 0 1 1 1 1 Sec3 exocyst complex subunit Sec3-PIP2_bind PF15277.1 EPY51851.1 - 3.8e-14 52.3 0.0 6.8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EPY51851.1 - 2.3e-05 22.7 1.5 2.3e-05 22.7 1.1 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec3 Pkinase PF00069.20 EPY51852.1 - 3e-67 226.5 0.0 5.6e-67 225.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51852.1 - 1e-38 132.9 0.0 3.5e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase HR1 PF02185.11 EPY51852.1 - 1e-21 76.4 11.7 1.6e-11 43.7 1.7 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EPY51852.1 - 4.1e-19 68.0 28.4 1.3e-10 40.8 6.4 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EPY51852.1 - 2.7e-08 34.1 0.5 1.3e-07 32.0 0.3 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.25 EPY51852.1 - 5.1e-05 23.0 0.1 0.00012 21.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.1 EPY51852.1 - 0.016 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF892 PF05974.7 EPY51852.1 - 0.023 14.5 0.7 0.052 13.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Kdo PF06293.9 EPY51852.1 - 0.052 12.5 0.0 0.14 11.1 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 EPY51852.1 - 0.48 10.1 25.4 0.016 14.8 4.3 2.5 2 0 0 2 2 2 0 PHD-finger ADIP PF11559.3 EPY51852.1 - 2.9 7.7 12.8 0.064 13.1 3.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4452 PF14618.1 EPY51853.1 - 4.5e-14 52.6 5.5 5.7e-14 52.2 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) DUF137 PF02006.11 EPY51853.1 - 0.019 14.3 0.1 0.028 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF137 Hamartin PF04388.7 EPY51853.1 - 0.047 12.3 1.1 0.053 12.2 0.8 1.0 1 0 0 1 1 1 0 Hamartin protein IBN_N PF03810.14 EPY51854.1 - 1.3e-13 50.6 0.2 2.1e-12 46.8 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EPY51854.1 - 1.8e-05 24.9 6.0 0.45 10.8 0.2 5.5 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 EPY51854.1 - 0.01 15.8 4.2 35 4.8 0.1 6.1 5 0 0 5 5 5 0 HEAT repeat Xpo1 PF08389.7 EPY51854.1 - 0.02 14.8 0.2 0.02 14.8 0.1 4.6 5 1 0 5 5 5 0 Exportin 1-like protein Arm PF00514.18 EPY51854.1 - 0.53 10.2 5.9 16 5.5 0.1 4.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Metallophos PF00149.23 EPY51855.1 - 3.2e-44 150.7 0.2 3.9e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clp1 PF06807.9 EPY51856.1 - 7.4e-20 71.5 0.0 3.1e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPY51856.1 - 3e-09 36.7 0.0 6.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EPY51856.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EPY51856.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain YqzH PF14164.1 EPY51856.1 - 0.024 14.5 0.1 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 YqzH-like protein SRPRB PF09439.5 EPY51856.1 - 0.059 12.5 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EPY51856.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPY51856.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Metallothio_Euk PF12749.2 EPY51857.1 - 0.0072 16.3 39.9 0.0084 16.1 27.7 1.1 1 0 0 1 1 1 1 Eukaryotic metallothionein Metallothio PF00131.15 EPY51857.1 - 0.37 10.7 41.7 1.2 9.0 28.9 1.7 1 1 0 1 1 1 0 Metallothionein SH3_1 PF00018.23 EPY51858.1 - 4.3e-27 93.2 0.0 7.1e-14 50.9 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EPY51858.1 - 9.3e-16 57.0 0.0 6.4e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 EPY51858.1 - 7.7e-14 51.0 0.0 2.9e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EPY51858.1 - 7.8e-12 44.9 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EPY51858.1 - 6.9e-06 25.6 0.0 1.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PB1 domain SH3_3 PF08239.6 EPY51858.1 - 0.16 12.1 0.0 2.3 8.4 0.0 2.8 4 0 0 4 4 4 0 Bacterial SH3 domain DUF2009 PF09418.5 EPY51859.1 - 1e-205 683.9 0.3 1.1e-205 683.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) V-ATPase_H_N PF03224.9 EPY51860.1 - 0.0044 16.1 2.9 0.026 13.6 0.2 2.3 2 0 0 2 2 2 2 V-ATPase subunit H LRR_8 PF13855.1 EPY51861.1 - 9.4e-06 25.2 33.8 0.00038 20.1 5.4 4.6 3 1 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EPY51861.1 - 2.1e-05 24.0 39.0 0.00018 21.0 3.8 6.2 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EPY51861.1 - 0.0004 19.9 7.6 0.0071 15.9 0.3 3.5 1 1 1 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.28 EPY51861.1 - 7.8 6.9 26.2 11 6.5 0.6 7.1 4 4 1 5 5 5 0 Leucine Rich Repeat CRF1 PF10380.4 EPY51862.1 - 0.52 10.6 14.6 0.57 10.5 4.0 3.9 2 2 0 2 2 2 0 Transcription factor CRF1 GDI PF00996.13 EPY51863.1 - 1.2e-219 729.0 0.0 1.4e-219 728.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.19 EPY51863.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Hormone_2 PF00123.15 EPY51863.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Peptide hormone WD40 PF00400.27 EPY51864.1 - 1.4e-34 116.6 10.5 2.7e-10 39.7 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EPY51864.1 - 2.5e-06 27.2 1.4 0.53 9.9 0.0 4.2 1 1 3 4 4 4 3 Transcription factor IIIC subunit delta N-term CARDB PF07705.6 EPY51864.1 - 0.11 12.5 0.0 23 5.1 0.0 3.1 2 1 1 3 3 3 0 CARDB NTF2 PF02136.15 EPY51865.1 - 4e-34 117.5 0.3 4.4e-34 117.3 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EPY51865.1 - 0.025 13.6 0.4 0.11 11.4 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Glyco_transf_52 PF07922.6 EPY51865.1 - 0.033 13.2 0.0 0.064 12.2 0.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 52 Pkinase PF00069.20 EPY51866.1 - 5.2e-70 235.5 0.0 8.1e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51866.1 - 2.2e-29 102.2 0.0 3.5e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPY51866.1 - 2.2e-09 37.6 5.8 7.6e-09 35.9 4.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPY51866.1 - 1e-07 31.2 0.0 1.9e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EPY51866.1 - 0.0031 17.3 0.1 0.055 13.3 0.0 2.7 2 1 0 2 2 2 1 C2 domain APH PF01636.18 EPY51866.1 - 0.005 16.6 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family TruD PF01142.13 EPY51866.1 - 0.013 14.2 0.1 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) Brix PF04427.13 EPY51867.1 - 3.2e-54 183.4 0.5 5.5e-54 182.7 0.3 1.3 1 0 0 1 1 1 1 Brix domain Med19 PF10278.4 EPY51867.1 - 0.71 9.5 14.0 0.75 9.4 8.5 1.9 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.5 EPY51867.1 - 7 6.4 8.9 15 5.3 6.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mus7 PF09462.5 EPY51868.1 - 3.7e-110 369.6 21.0 3.7e-110 369.6 14.5 2.2 2 0 0 2 2 2 1 Mus7/MMS22 family HbrB PF08539.6 EPY51869.1 - 3e-26 92.1 0.8 4.2e-26 91.6 0.5 1.2 1 0 0 1 1 1 1 HbrB-like Aminotran_4 PF01063.14 EPY51869.1 - 0.0095 15.4 0.1 1.4 8.3 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class IV Gon7 PF08738.5 EPY51870.1 - 0.00031 20.7 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Gon7 family HOOK PF05622.7 EPY51870.1 - 0.099 10.4 0.3 0.1 10.3 0.2 1.0 1 0 0 1 1 1 0 HOOK protein Aminotran_1_2 PF00155.16 EPY51871.1 - 1.3e-68 231.5 0.0 1.5e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPY51871.1 - 7.6e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EPY51871.1 - 2.3e-05 23.7 0.0 4.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPY51871.1 - 0.00011 20.5 0.0 0.00033 19.0 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPY51871.1 - 0.00031 19.6 0.0 0.017 13.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V OKR_DC_1 PF01276.15 EPY51871.1 - 0.18 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain PAPA-1 PF04795.7 EPY51872.1 - 1.1e-24 86.9 3.7 1.1e-24 86.9 2.5 3.7 3 1 1 4 4 4 1 PAPA-1-like conserved region PP1_bind PF15276.1 EPY51872.1 - 0.42 10.6 5.0 8.3 6.5 0.2 3.0 3 0 0 3 3 3 0 Protein phosphatase 1 binding Neugrin PF06413.6 EPY51873.1 - 1.4e-05 25.0 0.1 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EPY51873.1 - 1.6e-05 24.8 1.1 3e-05 24.0 0.8 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Sigma70_r4 PF04545.11 EPY51873.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 SPX PF03105.14 EPY51874.1 - 6.3e-35 121.2 5.0 1.2e-34 120.3 3.5 1.5 1 1 0 1 1 1 1 SPX domain zf-RING_2 PF13639.1 EPY51874.1 - 2.9e-07 30.2 9.6 7.3e-07 28.9 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EPY51874.1 - 4.8e-06 26.3 11.4 7e-06 25.8 7.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EPY51874.1 - 1.4e-05 24.6 7.2 2.7e-05 23.7 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY51874.1 - 3.6e-05 23.3 9.8 9.1e-05 22.0 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY51874.1 - 7.2e-05 22.7 11.0 0.0002 21.3 7.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY51874.1 - 0.00081 19.0 8.4 0.0021 17.7 5.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EPY51874.1 - 0.0019 17.9 3.3 0.0041 16.8 2.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EPY51874.1 - 0.0082 15.6 4.1 0.025 14.1 2.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EPY51874.1 - 0.014 14.9 2.1 0.039 13.5 1.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EPY51874.1 - 0.12 12.5 8.5 0.63 10.1 5.9 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EPY51874.1 - 0.14 12.0 4.4 0.085 12.7 1.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EPY51874.1 - 2.2 7.8 9.7 5.9 6.4 6.3 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EPY51874.1 - 9.8 5.7 11.8 1.2 8.7 4.9 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_UBOX PF13445.1 EPY51874.1 - 9.8 5.9 12.3 0.16 11.7 2.8 2.4 3 0 0 3 3 3 0 RING-type zinc-finger DnaJ PF00226.26 EPY51875.1 - 1.2e-21 76.2 0.3 1.2e-21 76.2 0.2 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EPY51875.1 - 1.3e-08 34.7 5.6 3.8e-08 33.2 3.9 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPY51875.1 - 2.8e-07 30.4 4.2 6.3e-07 29.3 2.9 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EPY51875.1 - 0.0002 21.4 1.3 0.00081 19.4 0.9 2.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF241 PF03087.9 EPY51875.1 - 0.005 16.3 4.0 0.005 16.3 2.7 2.0 2 0 0 2 2 2 1 Arabidopsis protein of unknown function zf-C2H2 PF00096.21 EPY51875.1 - 0.0097 16.1 2.0 0.028 14.7 1.4 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF4188 PF13826.1 EPY51875.1 - 0.035 14.2 1.0 0.067 13.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) zf-C2H2_4 PF13894.1 EPY51875.1 - 0.04 14.2 1.2 0.13 12.6 0.8 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Rsa3 PF14615.1 EPY51876.1 - 9.1e-16 56.8 0.2 1.3e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 CCDC66 PF15236.1 EPY51876.1 - 0.0071 15.9 1.6 0.0084 15.7 1.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 66 Alpha-amylase PF00128.19 EPY51876.1 - 0.039 13.3 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain tRNA_m1G_MT PF01746.16 EPY51877.1 - 1.5e-46 158.3 0.5 2.6e-46 157.5 0.3 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF1975 PF09318.5 EPY51877.1 - 0.027 14.0 0.3 0.065 12.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1975) DNA_primase_S PF01896.14 EPY51878.1 - 1.6e-56 190.1 0.1 8.7e-56 187.7 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit Drc1-Sld2 PF11719.3 EPY51879.1 - 5.7e-46 157.4 30.5 2.8e-28 99.1 8.9 2.1 1 1 1 2 2 2 2 DNA replication and checkpoint protein DUF3125 PF11323.3 EPY51879.1 - 0.02 14.6 0.6 7.4 6.4 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3125) TPR_11 PF13414.1 EPY51880.1 - 5.2e-45 150.9 18.6 9.1e-14 50.8 0.0 7.2 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 EPY51880.1 - 7.7e-33 110.7 13.5 6.7e-06 25.4 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPY51880.1 - 7.5e-29 97.3 14.9 4.4e-05 23.0 0.0 10.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPY51880.1 - 2.6e-21 75.7 0.8 0.00043 20.8 0.5 6.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPY51880.1 - 3.6e-16 58.8 15.3 2.4e-05 24.1 0.7 6.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EPY51880.1 - 1.2e-12 46.9 4.3 1.8 8.9 0.0 8.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPY51880.1 - 4.4e-11 42.3 6.8 0.79 10.5 0.0 8.4 5 3 4 10 10 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPY51880.1 - 1.9e-10 39.7 21.3 0.071 12.9 0.0 9.5 11 1 0 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPY51880.1 - 5.2e-08 32.1 6.8 0.038 13.7 0.2 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY51880.1 - 6.1e-08 32.8 16.0 0.00013 22.2 1.4 6.0 4 2 2 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EPY51880.1 - 4.8e-07 29.8 19.5 0.0061 16.6 0.7 5.4 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EPY51880.1 - 5.1e-05 22.4 1.2 0.065 12.4 0.1 3.8 4 0 0 4 4 4 1 SHNi-TPR TPR_9 PF13371.1 EPY51880.1 - 0.00076 19.2 1.8 0.15 11.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPY51880.1 - 0.0061 16.4 2.6 2.9 7.9 0.3 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat NeA_P2 PF12312.3 EPY51880.1 - 0.018 14.2 0.1 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein TPR_6 PF13174.1 EPY51880.1 - 0.057 13.8 16.4 0.28 11.7 0.0 6.4 8 0 0 8 8 5 0 Tetratricopeptide repeat DUF1510 PF07423.6 EPY51880.1 - 0.087 12.1 11.8 0.18 11.1 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Chorion_2 PF03964.10 EPY51880.1 - 6.1 7.4 15.5 34 5.0 3.9 3.8 2 1 1 4 4 4 0 Chorion family 2 TPR_3 PF07720.7 EPY51880.1 - 6.7 6.6 15.1 13 5.7 0.3 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat PPI_Ypi1 PF07491.6 EPY51881.1 - 5.8e-10 38.6 0.9 9.8e-10 37.9 0.6 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor Mago_nashi PF02792.9 EPY51881.1 - 0.071 12.8 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Mago nashi protein DUF4588 PF15251.1 EPY51882.1 - 0.0045 16.9 1.9 0.0053 16.7 0.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) WD40 PF00400.27 EPY51883.1 - 1.5e-66 218.0 33.7 1.9e-13 49.6 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPY51883.1 - 1.9e-06 26.3 4.9 0.099 10.7 0.1 3.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY51883.1 - 0.0011 17.7 3.2 0.4 9.3 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.6 EPY51883.1 - 0.0013 18.4 0.5 1.2 8.8 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EPY51883.1 - 0.003 15.8 0.0 1.4 7.1 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EPY51883.1 - 0.19 11.4 2.2 3.7 7.3 0.0 3.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat DUF999 PF06198.6 EPY51885.1 - 0.011 15.4 3.4 0.028 14.2 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF999) FA_desaturase PF00487.19 EPY51885.1 - 2.7 7.3 6.8 4.2 6.7 4.7 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DUF4451 PF14616.1 EPY51886.1 - 6.3e-33 113.2 7.5 1.2e-32 112.2 5.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) eIF-5_eIF-2B PF01873.12 EPY51887.1 - 2.4e-45 153.2 0.2 3.8e-45 152.5 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EPY51887.1 - 5.9e-05 22.2 0.3 0.00014 21.1 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.10 EPY51887.1 - 0.0081 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Hid1 PF12722.2 EPY51887.1 - 0.87 7.1 7.6 1.1 6.8 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1708 PF08101.6 EPY51888.1 - 3.5e-72 243.5 7.4 3.5e-72 243.5 5.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) DUF4449 PF14613.1 EPY51889.1 - 3.9e-39 134.2 0.8 3.9e-39 134.2 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Cauli_AT PF03233.8 EPY51889.1 - 2.8 7.6 9.5 0.59 9.8 2.6 2.7 3 0 0 3 3 3 0 Aphid transmission protein Homeobox PF00046.24 EPY51890.1 - 1.8e-15 56.2 0.5 5e-15 54.8 0.3 1.8 1 0 0 1 1 1 1 Homeobox domain Trp_syntA PF00290.15 EPY51891.1 - 4.9e-85 284.1 0.1 7.1e-85 283.6 0.1 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EPY51891.1 - 7.7e-47 159.9 0.2 1.2e-46 159.3 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KRAP_IP3R_bind PF14722.1 EPY51891.1 - 0.064 12.8 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain PTH2 PF01981.11 EPY51892.1 - 2.1e-45 153.1 0.4 3e-45 152.6 0.3 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 U1snRNP70_N PF12220.3 EPY51893.1 - 2.4e-30 104.7 4.5 3.7e-30 104.0 3.1 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EPY51893.1 - 1.3e-18 66.3 0.0 1.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51893.1 - 2.3e-13 49.9 0.0 3.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51893.1 - 2.9e-08 33.4 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GBP PF02263.14 EPY51893.1 - 0.041 12.9 0.1 0.057 12.4 0.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DCP2 PF05026.8 EPY51894.1 - 1.6e-36 124.0 2.9 2.2e-36 123.5 0.7 2.1 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 EPY51894.1 - 1.4e-14 53.8 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Miro PF08477.8 EPY51895.1 - 0.011 16.2 0.0 0.029 14.8 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein MCM PF00493.18 EPY51895.1 - 0.016 13.9 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 EPY51895.1 - 0.033 15.0 0.1 0.07 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPY51895.1 - 0.037 14.3 0.3 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EPY51895.1 - 0.045 13.7 0.4 0.095 12.6 0.1 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase FDX-ACB PF03147.9 EPY51895.1 - 0.059 13.5 0.2 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Ferredoxin-fold anticodon binding domain Adaptin_binding PF10199.4 EPY51895.1 - 0.072 13.3 0.6 0.46 10.7 0.4 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 zf-RING_5 PF14634.1 EPY51896.1 - 4.8e-07 29.3 5.7 7.3e-07 28.8 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPY51896.1 - 6.9e-05 22.7 3.0 0.00016 21.6 2.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY51896.1 - 0.0029 17.4 4.5 0.0048 16.6 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY51896.1 - 0.003 17.1 5.3 0.0054 16.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPY51896.1 - 0.01 15.5 2.6 0.019 14.6 1.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-CHY PF05495.7 EPY51896.1 - 0.017 15.2 3.0 0.028 14.5 2.1 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-C3HC4 PF00097.20 EPY51896.1 - 0.025 14.2 3.6 0.086 12.5 2.7 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Elf1 PF05129.8 EPY51896.1 - 0.027 14.1 1.1 0.057 13.1 0.8 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Fer2_3 PF13085.1 EPY51896.1 - 0.066 13.0 1.0 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF3133 PF11331.3 EPY51896.1 - 0.18 11.3 2.3 0.53 9.8 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) zf-C3HC4_4 PF15227.1 EPY51896.1 - 0.33 10.8 5.6 0.2 11.5 1.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Cytochrome_C7 PF14522.1 EPY51896.1 - 0.92 9.1 4.7 1.6 8.4 3.3 1.3 1 0 0 1 1 1 0 Cytochrome c7 Yos1 PF08571.5 EPY51897.1 - 3.9e-30 103.7 1.5 4.4e-30 103.6 1.1 1.0 1 0 0 1 1 1 1 Yos1-like TMEM237 PF15383.1 EPY51897.1 - 0.069 12.2 0.0 0.086 11.9 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 DUF3671 PF12420.3 EPY51897.1 - 0.13 12.2 1.4 0.19 11.6 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function MIF4G PF02854.14 EPY51898.1 - 5.1e-51 173.0 14.3 1.8e-23 83.0 1.3 3.5 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EPY51898.1 - 1.9e-32 112.3 23.1 1.9e-32 112.3 16.0 2.2 3 0 0 3 3 3 1 Up-frameshift suppressor 2 DUF4502 PF14950.1 EPY51898.1 - 0.0087 15.2 12.2 0.015 14.4 8.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) Nop14 PF04147.7 EPY51898.1 - 0.022 12.7 23.5 0.06 11.2 16.3 1.7 1 0 0 1 1 1 0 Nop14-like family Alg6_Alg8 PF03155.10 EPY51899.1 - 5.4e-156 520.0 37.4 6.4e-156 519.8 25.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Endonuclease_NS PF01223.18 EPY51900.1 - 4.9e-59 199.4 0.0 6e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-Tim10_DDP PF02953.10 EPY51901.1 - 6.8e-11 41.3 0.1 9.4e-11 40.8 0.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PQ-loop PF04193.9 EPY51902.1 - 7.1e-36 121.5 14.9 3.5e-19 68.1 2.0 2.9 4 0 0 4 4 4 2 PQ loop repeat MtN3_slv PF03083.11 EPY51902.1 - 0.0076 16.0 0.3 0.0076 16.0 0.2 2.8 3 1 1 4 4 4 2 Sugar efflux transporter for intercellular exchange NfeD PF01957.13 EPY51902.1 - 0.012 15.7 2.2 8.5 6.5 0.1 3.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Frag1 PF10277.4 EPY51902.1 - 0.62 9.5 10.4 0.082 12.3 2.7 2.3 2 1 0 2 2 2 0 Frag1/DRAM/Sfk1 family DUF3278 PF11683.3 EPY51902.1 - 0.65 10.0 0.0 0.65 10.0 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3278) DUF572 PF04502.8 EPY51903.1 - 0.0012 18.1 21.7 0.0015 17.7 15.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) YABBY PF04690.8 EPY51903.1 - 0.03 14.5 1.5 0.03 14.5 1.1 2.2 1 1 1 2 2 2 0 YABBY protein Tox-HDC PF15656.1 EPY51903.1 - 0.15 12.2 2.5 0.27 11.4 0.2 2.1 1 1 2 3 3 3 0 Toxin with a H, D/N and C signature BCS1_N PF08740.6 EPY51903.1 - 0.25 10.9 4.5 1.1 8.8 3.1 2.0 1 1 0 1 1 1 0 BCS1 N terminal DUF4640 PF15480.1 EPY51903.1 - 0.3 10.6 16.6 0.4 10.1 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) Alpha_GJ PF03229.8 EPY51903.1 - 0.61 10.4 6.8 0.95 9.8 4.7 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J GEMIN8 PF15348.1 EPY51903.1 - 1.2 9.1 17.3 1.7 8.6 12.0 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 APG6 PF04111.7 EPY51903.1 - 2.1 7.2 22.9 2.9 6.8 15.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Birna_RdRp PF04197.7 EPY51903.1 - 2.2 6.2 12.5 2.5 5.9 8.7 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) HSD3 PF15244.1 EPY51903.1 - 2.6 7.1 16.9 3.6 6.7 11.7 1.1 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase Asp-B-Hydro_N PF05279.6 EPY51903.1 - 2.7 7.7 17.6 3.9 7.2 12.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF342 PF03961.8 EPY51903.1 - 3.1 6.1 14.2 4.4 5.6 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LMBR1 PF04791.11 EPY51903.1 - 4.5 5.7 7.6 5.2 5.5 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein OmpH PF03938.9 EPY51903.1 - 8 6.3 26.0 1.3 8.9 15.6 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Motile_Sperm PF00635.21 EPY51904.1 - 1.5e-25 88.9 0.1 4.5e-25 87.3 0.0 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain PAT1 PF09770.4 EPY51904.1 - 0.19 9.9 11.5 0.23 9.6 8.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EPY51904.1 - 1.4 8.2 19.7 1.6 8.0 13.7 1.2 1 0 0 1 1 1 0 Vta1 like Cut8_C PF08559.5 EPY51905.1 - 1.2e-41 141.9 0.4 1.8e-41 141.2 0.3 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EPY51905.1 - 3e-11 42.9 1.1 6.6e-11 41.8 0.8 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Pex19 PF04614.7 EPY51906.1 - 1.8e-27 96.5 7.9 2.5e-27 96.0 5.5 1.1 1 0 0 1 1 1 1 Pex19 protein family RRN3 PF05327.6 EPY51906.1 - 1.3 7.0 4.9 1.7 6.6 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PKI PF02827.11 EPY51906.1 - 2.1 8.4 6.0 0.66 10.1 1.6 2.0 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Hep_59 PF07052.6 EPY51907.1 - 0.12 12.8 3.2 0.074 13.4 1.0 1.6 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 LTXXQ PF07813.7 EPY51907.1 - 0.92 9.9 5.7 2.5 8.5 4.0 1.9 1 1 0 1 1 1 0 LTXXQ motif family protein MFS_1 PF07690.11 EPY51908.1 - 3.7e-30 104.8 40.3 3.7e-30 104.8 27.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_6 PF14259.1 EPY51909.1 - 3.2e-16 59.0 0.0 0.0019 18.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY51909.1 - 4.9e-12 45.3 0.4 0.0047 16.5 0.1 4.4 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 EPY51910.1 - 1.9e-40 138.2 0.3 3.1e-40 137.5 0.2 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) AFT PF08731.6 EPY51910.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor AFT Snf7 PF03357.16 EPY51911.1 - 1.9e-17 63.1 14.3 2.6e-17 62.7 9.9 1.1 1 0 0 1 1 1 1 Snf7 ThiF PF00899.16 EPY51911.1 - 0.26 11.1 1.6 0.58 9.9 0.5 1.8 1 1 0 2 2 2 0 ThiF family V_ATPase_I PF01496.14 EPY51911.1 - 5.4 4.7 7.9 6.9 4.3 5.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CS PF04969.11 EPY51912.1 - 9e-08 32.5 0.1 1.3e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 CS domain ABC_tran PF00005.22 EPY51913.1 - 1.7e-51 174.1 0.0 4e-28 98.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPY51913.1 - 1.3e-37 129.7 39.1 5.8e-20 71.8 8.8 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EPY51913.1 - 1.2e-14 54.0 0.6 0.00061 19.0 0.0 4.4 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPY51913.1 - 1.1e-09 37.6 0.4 0.00026 20.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EPY51913.1 - 1.5e-09 38.2 0.3 0.014 15.3 0.0 4.8 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EPY51913.1 - 2.1e-08 33.8 0.4 0.0012 18.3 0.0 3.3 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 EPY51913.1 - 5.9e-07 28.6 0.0 0.0058 15.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EPY51913.1 - 1.1e-06 28.2 0.1 0.038 13.4 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 EPY51913.1 - 1.2e-06 28.5 1.5 0.024 14.4 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_23 PF13476.1 EPY51913.1 - 1.4e-06 28.7 0.6 0.001 19.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPY51913.1 - 2.1e-05 25.3 0.0 0.083 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPY51913.1 - 4.3e-05 23.1 0.1 0.066 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EPY51913.1 - 5e-05 23.4 0.6 0.24 11.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPY51913.1 - 6.7e-05 22.1 0.0 0.037 13.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPY51913.1 - 0.0001 22.3 1.3 0.036 14.0 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EPY51913.1 - 0.00012 22.0 0.2 0.49 10.3 0.1 2.9 3 1 0 3 3 2 2 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EPY51913.1 - 0.00036 20.1 0.0 0.02 14.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EPY51913.1 - 0.00074 19.4 1.2 0.066 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EPY51913.1 - 0.00097 18.8 1.2 1 9.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EPY51913.1 - 0.0016 18.7 0.1 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EPY51913.1 - 0.002 18.6 0.0 1.7 9.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EPY51913.1 - 0.0027 17.5 0.6 0.19 11.5 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EPY51913.1 - 0.0037 16.4 1.5 0.89 8.6 0.0 2.9 3 0 0 3 3 2 1 AIG1 family Zeta_toxin PF06414.7 EPY51913.1 - 0.0083 15.2 0.8 0.3 10.1 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 EPY51913.1 - 0.009 16.2 0.7 0.96 9.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EPY51913.1 - 0.0096 14.8 0.2 1.2 7.8 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.10 EPY51913.1 - 0.011 15.5 0.0 3.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EPY51913.1 - 0.016 14.8 1.1 0.96 9.0 0.1 2.7 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 EPY51913.1 - 0.022 14.1 0.1 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2075 PF09848.4 EPY51913.1 - 0.022 13.7 0.2 4.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EPY51913.1 - 0.037 13.1 0.3 1.1 8.2 0.0 2.4 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.4 EPY51913.1 - 0.046 12.3 0.7 3.4 6.2 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 EPY51913.1 - 0.089 12.5 1.3 9.2 5.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPY51913.1 - 0.11 12.7 0.3 8.7 6.5 0.0 3.1 4 0 0 4 4 2 0 RNA helicase APS_kinase PF01583.15 EPY51913.1 - 0.34 10.5 1.5 22 4.6 0.0 3.8 4 0 0 4 4 4 0 Adenylylsulphate kinase AAA_19 PF13245.1 EPY51913.1 - 0.39 10.5 3.8 0.43 10.3 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain AAA_30 PF13604.1 EPY51913.1 - 0.47 10.0 0.2 14 5.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF4519 PF15012.1 EPY51913.1 - 0.69 9.8 2.4 1.8 8.5 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Aldedh PF00171.17 EPY51915.1 - 7.6e-184 611.3 0.0 8.7e-184 611.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LCD1 PF09798.4 EPY51916.1 - 5.7e-22 77.4 26.8 7.6e-12 44.0 2.7 3.9 3 2 0 3 3 3 2 DNA damage checkpoint protein Cortex-I_coil PF09304.5 EPY51916.1 - 0.0062 16.5 7.5 0.014 15.4 5.2 1.5 1 0 0 1 1 1 1 Cortexillin I, coiled coil SurA_N PF09312.6 EPY51916.1 - 0.0095 15.7 2.7 0.034 13.9 1.2 2.3 2 0 0 2 2 2 1 SurA N-terminal domain Ras PF00071.17 EPY51917.1 - 3.3e-67 224.8 0.1 4.6e-67 224.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY51917.1 - 1.3e-19 70.8 0.0 2.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY51917.1 - 4.4e-14 52.1 0.1 5.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY51917.1 - 3.6e-06 26.3 0.0 4.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPY51917.1 - 0.00036 20.0 0.1 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY51917.1 - 0.00042 20.2 0.0 0.00074 19.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPY51917.1 - 0.00093 18.4 0.1 0.0045 16.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EPY51917.1 - 0.0011 18.2 0.1 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EPY51917.1 - 0.018 15.0 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EPY51917.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EPY51917.1 - 0.059 12.6 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.24 EPY51917.1 - 0.067 13.4 0.1 1.3 9.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY51917.1 - 0.075 13.1 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPY51917.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EPY51917.1 - 0.2 10.3 2.3 10 4.6 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Thr_synth_N PF14821.1 EPY51918.1 - 1.8e-30 104.8 0.0 3.8e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EPY51918.1 - 1.4e-18 67.1 0.0 3.1e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Bap31 PF05529.7 EPY51920.1 - 1.3e-46 158.4 2.5 1.5e-46 158.2 1.7 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like IncA PF04156.9 EPY51920.1 - 0.0099 15.4 2.5 0.0099 15.4 1.7 1.6 2 0 0 2 2 2 1 IncA protein EzrA PF06160.7 EPY51920.1 - 0.079 11.1 4.9 0.11 10.6 3.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.3 EPY51920.1 - 2.7 7.8 13.6 3.8 7.3 9.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Aconitase PF00330.15 EPY51921.1 - 1.1e-185 617.5 0.0 1.3e-185 617.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPY51921.1 - 7.9e-41 139.2 0.0 1.4e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 EPY51922.1 - 2.8e-05 24.1 1.6 0.029 14.5 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EPY51922.1 - 0.0061 16.8 15.3 0.076 13.3 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPY51922.1 - 0.0093 16.2 22.9 0.06 13.7 0.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY51922.1 - 0.22 11.9 20.4 0.43 11.0 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPY51922.1 - 0.31 11.0 6.0 0.19 11.6 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Dus PF01207.12 EPY51923.1 - 4.3e-36 124.3 0.0 7.8e-35 120.1 0.0 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EPY51923.1 - 0.67 9.6 7.3 5.9 6.6 1.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidohydro_2 PF04909.9 EPY51924.1 - 1.9e-08 34.1 0.1 4.4e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EPY51924.1 - 5.6e-06 26.5 0.1 1.2e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPY51924.1 - 0.00029 20.5 0.1 0.00085 19.0 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPY51924.1 - 0.038 13.7 0.3 0.12 12.2 0.2 2.0 1 1 0 1 1 1 0 Amidohydrolase CoA_binding_2 PF13380.1 EPY51924.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain RRM_1 PF00076.17 EPY51925.1 - 4.5e-31 106.2 0.0 2.4e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51925.1 - 2.9e-22 78.3 0.0 1.6e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51925.1 - 8.9e-12 44.6 0.0 4.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPY51925.1 - 0.0095 15.7 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Ras PF00071.17 EPY51926.1 - 9.6e-48 161.6 0.0 1.1e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY51926.1 - 1.2e-15 58.0 0.0 1.9e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY51926.1 - 4.4e-06 26.0 0.0 6.8e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPY51926.1 - 0.0056 15.9 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPY51926.1 - 0.023 13.8 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EPY51926.1 - 0.025 14.0 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NST1 PF13945.1 EPY51927.1 - 4e-62 209.6 8.5 4e-62 209.6 5.9 4.5 3 1 1 4 4 4 2 Salt tolerance down-regulator TBP PF00352.16 EPY51929.1 - 3.9e-68 224.8 0.1 6.3e-35 118.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EPY51929.1 - 0.0013 18.7 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) tRNA-synt_1e PF01406.14 EPY51930.1 - 2e-142 473.7 0.1 6.5e-142 472.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EPY51930.1 - 7.7e-11 41.2 0.4 2.7e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPY51930.1 - 6.6e-06 24.4 0.0 0.0006 17.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EPY51930.1 - 0.00026 19.7 0.0 0.015 13.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) PMSR PF01625.16 EPY51931.1 - 1.8e-58 196.8 1.7 2.1e-58 196.6 1.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Cnd3 PF12719.2 EPY51931.1 - 0.03 13.3 0.1 0.039 12.9 0.1 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Nnf1 PF03980.9 EPY51932.1 - 1.7e-26 92.3 6.3 1.7e-26 92.3 4.4 2.3 3 0 0 3 3 3 1 Nnf1 Orbi_VP5 PF00901.12 EPY51932.1 - 0.055 11.6 3.8 0.085 11.0 2.6 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DIT1_PvcA PF05141.7 EPY51932.1 - 0.32 10.2 3.8 0.43 9.8 2.5 1.3 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF3186 PF11382.3 EPY51932.1 - 0.32 10.0 3.3 0.49 9.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) TnpV PF14198.1 EPY51932.1 - 0.46 10.3 7.1 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Transposon-encoded protein TnpV DUF1664 PF07889.7 EPY51932.1 - 3.2 7.5 6.1 2 8.2 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.10 EPY51932.1 - 3.8 7.4 7.4 1.2 9.0 1.7 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Occludin_ELL PF07303.8 EPY51932.1 - 6.4 7.5 9.6 1.6 9.5 2.8 2.4 2 1 0 2 2 2 0 Occludin homology domain Uso1_p115_head PF04869.9 EPY51933.1 - 2.6e-61 207.1 5.6 1e-60 205.1 3.9 2.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region WEMBL PF05701.6 EPY51933.1 - 0.11 10.9 84.2 0.067 11.6 27.4 3.0 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Filament PF00038.16 EPY51933.1 - 0.39 10.1 76.6 14 5.0 27.6 4.8 1 1 3 4 4 4 0 Intermediate filament protein IncA PF04156.9 EPY51933.1 - 0.73 9.4 99.1 0.12 11.9 9.7 6.1 2 1 5 7 7 7 0 IncA protein Reo_sigmaC PF04582.7 EPY51933.1 - 1.8 7.6 32.9 0.14 11.3 5.6 5.1 2 1 5 7 7 7 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EPY51933.1 - 1.9 5.6 71.6 0.48 7.6 17.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EPY51933.1 - 4.4 7.1 104.5 5.1 6.9 9.3 5.9 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EPY51933.1 - 6 6.6 90.4 2.2 8.0 15.7 5.0 1 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EPY51933.1 - 8.1 6.3 84.8 0.19 11.5 11.9 5.7 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding PRP3 PF08572.5 EPY51934.1 - 3e-66 222.9 8.9 3e-66 222.9 6.1 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EPY51934.1 - 5.9e-39 132.6 0.1 5.9e-39 132.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) WD40 PF00400.27 EPY51935.1 - 5.8e-51 168.6 16.4 8.1e-09 35.0 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EPY51935.1 - 5.9e-13 48.3 0.3 5.9e-13 48.3 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPY51935.1 - 1.9e-08 33.7 1.0 4.6e-08 32.5 0.7 1.7 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EPY51935.1 - 1.2e-07 30.2 0.8 0.00017 19.8 0.0 3.3 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY51935.1 - 0.013 14.2 6.1 0.084 11.6 0.4 3.8 1 1 2 3 3 3 0 Nup133 N terminal like BBS2_Mid PF14783.1 EPY51935.1 - 0.023 14.4 0.2 0.65 9.7 0.0 3.0 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EPY51935.1 - 0.076 12.4 0.0 0.59 9.5 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain PRANC PF09372.5 EPY51935.1 - 0.11 12.4 0.2 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 PRANC domain PQQ_3 PF13570.1 EPY51935.1 - 0.18 12.1 0.3 52 4.3 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain ABC_tran PF00005.22 EPY51936.1 - 1.5e-47 161.3 0.2 6.3e-27 94.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPY51936.1 - 1.5e-45 155.7 30.0 1.4e-24 86.9 7.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EPY51936.1 - 3e-14 52.7 6.8 0.0018 17.5 2.4 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPY51936.1 - 7.3e-11 42.5 10.9 5.3e-05 23.3 0.2 4.7 3 2 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EPY51936.1 - 4.3e-08 33.7 0.2 0.00015 22.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPY51936.1 - 1.1e-07 31.2 0.6 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPY51936.1 - 1.8e-07 30.4 0.0 0.00028 20.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPY51936.1 - 6e-06 25.7 0.3 0.033 13.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EPY51936.1 - 6e-06 26.3 0.8 0.033 14.1 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPY51936.1 - 1.6e-05 24.7 1.5 0.15 12.0 0.1 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPY51936.1 - 1.7e-05 24.4 0.0 0.061 12.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 EPY51936.1 - 5.1e-05 23.1 0.5 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_17 PF13207.1 EPY51936.1 - 7e-05 23.6 0.0 0.83 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EPY51936.1 - 7.9e-05 21.6 0.2 0.14 11.0 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EPY51936.1 - 8.7e-05 22.0 0.8 0.39 10.1 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain MobB PF03205.9 EPY51936.1 - 0.00016 21.4 0.7 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EPY51936.1 - 0.00039 20.7 0.0 0.68 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPY51936.1 - 0.00068 19.7 0.5 1.8 8.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EPY51936.1 - 0.00069 20.0 1.0 0.31 11.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EPY51936.1 - 0.0016 18.3 0.1 0.45 10.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPY51936.1 - 0.0044 16.1 0.1 0.16 11.0 0.0 2.5 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 EPY51936.1 - 0.0068 16.6 0.3 0.79 9.9 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EPY51936.1 - 0.017 14.9 4.1 0.072 12.9 0.6 2.6 2 0 0 2 2 2 0 Dynamin family Adeno_IVa2 PF02456.10 EPY51936.1 - 0.019 13.6 0.0 0.12 10.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 EPY51936.1 - 0.027 14.1 0.2 0.29 10.8 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase Guanylate_kin PF00625.16 EPY51936.1 - 0.062 12.7 0.5 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase NACHT PF05729.7 EPY51936.1 - 0.074 12.7 1.2 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.13 EPY51936.1 - 0.098 12.1 0.0 15 5.0 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EPY51936.1 - 0.11 11.4 0.5 5.3 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EPY51936.1 - 0.11 11.8 0.4 13 5.1 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EPY51936.1 - 0.11 11.9 0.5 5.6 6.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EPY51936.1 - 0.11 12.0 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPY51936.1 - 0.13 12.0 0.1 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EPY51936.1 - 0.13 12.4 0.3 7.1 6.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.24 EPY51936.1 - 0.19 11.1 0.3 16 4.9 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.9 EPY51936.1 - 0.23 11.1 2.6 24 4.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EPY51936.1 - 0.51 9.7 3.2 8.3 5.8 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 EPY51936.1 - 2.5 7.1 6.8 7.4 5.6 0.2 3.0 4 0 0 4 4 3 0 AIG1 family Translin PF01997.11 EPY51937.1 - 2.8e-38 131.5 3.4 3.5e-38 131.2 2.4 1.1 1 0 0 1 1 1 1 Translin family MCC-bdg_PDZ PF10506.4 EPY51937.1 - 0.011 15.5 2.5 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Filament PF00038.16 EPY51937.1 - 0.22 10.9 3.6 0.21 11.0 1.2 1.7 2 0 0 2 2 2 0 Intermediate filament protein bZIP_1 PF00170.16 EPY51937.1 - 4.5 7.3 5.4 28 4.7 0.2 2.6 3 0 0 3 3 3 0 bZIP transcription factor KTI12 PF08433.5 EPY51938.1 - 5e-96 321.0 0.1 5.6e-96 320.8 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EPY51938.1 - 5e-05 24.1 0.0 7.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY51938.1 - 0.00049 20.4 0.0 0.00076 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPY51938.1 - 0.00056 19.8 0.0 0.00098 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EPY51938.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 EPY51938.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPY51938.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPY51938.1 - 0.032 14.1 0.1 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3175 PF11373.3 EPY51938.1 - 0.049 13.6 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) Thymidylate_kin PF02223.12 EPY51938.1 - 0.067 12.5 0.4 0.15 11.4 0.3 1.6 1 1 0 1 1 1 0 Thymidylate kinase AAA PF00004.24 EPY51938.1 - 0.085 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EPY51938.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 EPY51938.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec7 PF01369.15 EPY51939.1 - 3.2e-67 225.8 2.0 5.3e-67 225.1 0.5 2.1 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EPY51939.1 - 3.6e-46 156.6 4.9 3.6e-46 156.6 3.4 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPY51939.1 - 4.2e-30 103.1 12.8 1.2e-27 95.2 0.3 6.5 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) La PF05383.12 EPY51940.1 - 4.8e-20 71.1 0.1 8.1e-20 70.3 0.1 1.4 1 0 0 1 1 1 1 La domain Got1 PF04178.7 EPY51941.1 - 2.1e-25 89.1 17.0 2.8e-25 88.7 11.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF485 PF04341.7 EPY51941.1 - 0.35 10.5 9.4 0.025 14.2 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Alpha-amylase PF00128.19 EPY51942.1 - 8e-29 101.0 0.3 3.8e-26 92.2 0.2 3.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPY51942.1 - 2e-14 53.7 0.0 3.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPY51942.1 - 2.9e-08 33.3 0.0 6.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EPY51942.1 - 0.054 14.1 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain Alpha-amylase PF00128.19 EPY51943.1 - 6e-63 213.1 3.8 6e-63 213.1 2.6 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPY51943.1 - 2.4e-09 37.1 0.0 5.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EPY51943.1 - 0.00051 19.0 0.1 0.0011 17.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 GHL6 PF14871.1 EPY51943.1 - 0.031 14.3 0.1 8.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Sec7_N PF12783.2 EPY51944.1 - 1.6e-30 105.7 4.7 1.6e-30 105.7 3.3 5.1 5 1 1 6 6 6 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPY51944.1 - 2.3e-05 23.8 0.1 0.0084 15.6 0.0 3.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1981) Inhibitor_I78 PF11720.3 EPY51945.1 - 2.5e-09 36.7 0.0 3.1e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EPY51945.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Potato inhibitor I family DUF2674 PF10879.3 EPY51946.1 - 0.038 13.7 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) adh_short PF00106.20 EPY51947.1 - 1.3e-20 73.9 0.1 1.8e-20 73.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY51947.1 - 5.5e-15 55.7 0.2 6.8e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY51947.1 - 1.5e-06 27.9 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPY51947.1 - 3.8e-06 26.2 0.2 0.0034 16.5 0.1 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EPY51947.1 - 8.7e-05 22.5 0.0 0.00025 21.1 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EPY51947.1 - 0.0015 18.0 0.2 0.0022 17.4 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPY51947.1 - 0.003 16.8 0.1 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Glyco_hydro_81 PF03639.8 EPY51948.1 - 1.3e-243 810.0 21.6 1.6e-243 809.7 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Spt4 PF06093.8 EPY51948.1 - 0.14 12.0 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger KH_1 PF00013.24 EPY51949.1 - 0.0028 17.2 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EPY51949.1 - 0.021 14.4 0.1 0.043 13.4 0.1 1.5 1 0 0 1 1 1 0 KH domain SLS PF14611.1 EPY51949.1 - 0.4 10.0 5.4 0.1 12.0 0.6 2.1 2 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Actin PF00022.14 EPY51950.1 - 7.2e-133 442.8 0.0 8.8e-133 442.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPY51950.1 - 1.7e-08 33.4 0.1 0.0025 16.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 EPY51950.1 - 0.02 13.8 0.1 0.07 12.0 0.0 1.8 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Proteasome PF00227.21 EPY51951.1 - 2e-47 160.9 0.0 2.5e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EPY51951.1 - 3.4e-13 48.6 0.1 7.4e-13 47.5 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_N PF01210.18 EPY51953.1 - 1.2e-53 181.0 0.0 4.4e-53 179.2 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPY51953.1 - 1e-51 174.5 0.2 2.1e-51 173.5 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EPY51953.1 - 0.037 14.4 0.1 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RabGAP-TBC PF00566.13 EPY51954.1 - 4.7e-28 98.1 3.3 4.7e-28 98.1 2.3 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AAA PF00004.24 EPY51955.1 - 5.5e-15 55.7 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EPY51955.1 - 1.2e-14 54.0 0.1 2.8e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPY51955.1 - 3.9e-14 52.6 0.0 2.7e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EPY51955.1 - 1.7e-07 30.3 0.1 0.0027 16.4 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EPY51955.1 - 5.3e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPY51955.1 - 5.4e-05 23.3 0.1 0.0038 17.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPY51955.1 - 6.9e-05 21.8 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EPY51955.1 - 7.7e-05 22.3 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EPY51955.1 - 0.0002 20.9 0.0 0.00056 19.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EPY51955.1 - 0.00024 20.2 0.0 0.0006 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPY51955.1 - 0.00081 19.4 0.5 0.017 15.0 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EPY51955.1 - 0.0023 17.4 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.1 EPY51955.1 - 0.0054 16.3 0.3 0.022 14.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPY51955.1 - 0.0068 15.5 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EPY51955.1 - 0.014 14.9 0.0 0.05 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.3 EPY51955.1 - 0.016 15.0 0.6 0.29 10.8 0.0 2.7 2 1 1 3 3 3 0 DNA polymerase III subunits gamma and tau domain III DUF2075 PF09848.4 EPY51955.1 - 0.018 14.0 0.0 0.05 12.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EPY51955.1 - 0.022 14.2 0.1 0.06 12.8 0.0 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 EPY51955.1 - 0.026 14.2 0.0 0.08 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPY51955.1 - 0.029 13.9 0.0 0.087 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EPY51955.1 - 0.029 13.8 0.2 0.45 9.8 0.1 2.8 1 1 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EPY51955.1 - 0.031 13.6 0.0 0.097 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EPY51955.1 - 0.037 13.9 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPY51955.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 EPY51955.1 - 0.082 11.5 0.0 0.23 10.0 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 EPY51955.1 - 0.12 11.9 0.0 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SNF2_N PF00176.18 EPY51955.1 - 0.15 10.8 0.0 3.1 6.5 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain PWWP PF00855.12 EPY51956.1 - 1.6e-07 31.3 0.7 7.6e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 PWWP domain TRAP_alpha PF03896.11 EPY51956.1 - 0.61 9.0 5.3 1.2 8.0 3.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HEAT_2 PF13646.1 EPY51957.1 - 6.3e-17 61.6 7.5 0.00033 20.8 0.0 7.9 7 1 1 8 8 8 4 HEAT repeats SF3b1 PF08920.5 EPY51957.1 - 1.2e-15 57.8 6.2 1.2e-15 57.8 4.3 2.9 2 2 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.17 EPY51957.1 - 1.7e-14 52.5 7.4 0.035 14.1 0.0 10.3 10 0 0 10 10 9 3 HEAT repeat HEAT_EZ PF13513.1 EPY51957.1 - 1e-13 51.2 4.7 0.14 12.6 0.0 8.0 7 2 1 8 8 7 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPY51957.1 - 4.7e-07 30.1 0.8 1 9.8 0.0 5.8 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 EPY51957.1 - 0.00015 21.1 0.5 0.33 10.2 0.0 4.5 5 0 0 5 5 5 1 NUC173 domain CLASP_N PF12348.3 EPY51957.1 - 0.00029 20.2 0.7 1.5 8.1 0.0 3.4 4 0 0 4 4 4 2 CLASP N terminal Adaptin_N PF01602.15 EPY51957.1 - 0.00044 18.7 0.7 0.016 13.5 0.2 3.1 1 1 0 1 1 1 1 Adaptin N terminal region Arm PF00514.18 EPY51957.1 - 0.00072 19.2 2.6 3.8 7.4 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 EPY51957.1 - 0.0019 17.8 0.1 0.06 12.9 0.0 3.3 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central DUF3385 PF11865.3 EPY51957.1 - 0.0023 17.8 3.2 0.22 11.4 0.1 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Dopey_N PF04118.9 EPY51957.1 - 0.004 15.9 1.2 0.24 10.1 0.0 3.4 3 1 0 3 3 3 1 Dopey, N-terminal CRM1_C PF08767.6 EPY51957.1 - 0.0041 16.0 0.2 0.013 14.4 0.1 1.8 1 0 0 1 1 1 1 CRM1 C terminal Cnd1 PF12717.2 EPY51957.1 - 0.0056 16.5 2.3 19 5.0 0.0 4.9 6 1 1 7 7 6 0 non-SMC mitotic condensation complex subunit 1 D5_N PF08706.6 EPY51957.1 - 0.03 14.4 1.0 5.5 7.0 0.1 2.8 1 1 0 2 2 2 0 D5 N terminal like DUF4533 PF15047.1 EPY51957.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) Nramp PF01566.13 EPY51958.1 - 2.2e-93 312.9 18.4 3.3e-93 312.3 12.8 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Ribophorin_I PF04597.9 EPY51959.1 - 1.6e-109 366.2 7.8 1.9e-109 366.0 5.4 1.0 1 0 0 1 1 1 1 Ribophorin I FDC-SP PF15215.1 EPY51959.1 - 0.076 13.3 0.3 0.28 11.5 0.2 2.0 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide FKBP_C PF00254.23 EPY51960.1 - 6e-28 96.7 0.0 5e-27 93.7 0.0 2.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Hid1 PF12722.2 EPY51960.1 - 0.43 8.2 8.3 0.53 7.9 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dynamin_N PF00350.18 EPY51960.1 - 0.75 9.5 5.3 3.4 7.4 2.3 2.2 2 0 0 2 2 2 0 Dynamin family Neur_chan_memb PF02932.11 EPY51960.1 - 3.2 7.5 6.4 5.7 6.7 4.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 EPY51960.1 - 4.7 5.3 16.9 5.2 5.1 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIF_alpha PF05793.7 EPY51960.1 - 6.5 5.0 45.3 1.4 7.1 26.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Aminotran_3 PF00202.16 EPY51961.1 - 1.1e-70 238.2 0.0 1.4e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Nuf2 PF03800.9 EPY51962.1 - 8.4e-33 113.4 1.8 8.4e-33 113.4 1.3 2.7 2 1 0 2 2 2 1 Nuf2 family Glyco_hyd_65N_2 PF14498.1 EPY51962.1 - 0.095 12.3 0.7 0.23 11.1 0.5 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF2265 PF10023.4 EPY51962.1 - 1.7 7.6 18.4 1.2 8.2 2.2 2.3 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) Peptidase_C12 PF01088.16 EPY51963.1 - 1.7e-51 174.4 0.0 1.9e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DNA_pol3_delta PF06144.8 EPY51963.1 - 0.0072 15.8 0.1 0.087 12.3 0.0 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit Nop25 PF09805.4 EPY51963.1 - 0.039 14.0 1.9 0.057 13.5 1.3 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.2 EPY51964.1 - 1.5e-37 128.5 35.8 1.9e-37 128.2 24.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EPY51964.1 - 1.6e-11 43.7 38.7 1.4e-06 27.6 6.2 3.0 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.1 EPY51964.1 - 4.8e-05 22.6 31.1 0.0096 15.1 14.9 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 EPY51964.1 - 0.0022 17.9 0.8 0.0022 17.9 0.6 4.3 2 2 2 4 4 4 1 bZIP transcription factor CENP-F_leu_zip PF10473.4 EPY51964.1 - 0.0072 16.1 7.6 0.0072 16.1 5.3 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 EPY51964.1 - 0.0077 15.5 21.8 0.24 10.6 7.7 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) WEMBL PF05701.6 EPY51964.1 - 0.0081 14.6 32.6 0.01 14.3 22.6 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 EPY51964.1 - 0.0083 15.7 34.9 0.31 10.5 10.7 2.0 1 1 1 2 2 2 2 IncA protein Filament PF00038.16 EPY51964.1 - 0.012 15.1 29.8 0.069 12.6 14.3 2.6 1 1 1 2 2 2 0 Intermediate filament protein TMF_DNA_bd PF12329.3 EPY51964.1 - 0.014 15.1 34.1 0.24 11.2 5.6 4.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 EPY51964.1 - 0.024 14.5 16.9 0.17 11.7 0.1 3.9 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 EPY51964.1 - 0.029 11.7 30.2 0.05 10.9 20.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin PF02996.12 EPY51964.1 - 0.031 13.9 1.7 0.031 13.9 1.2 4.0 2 2 1 4 4 4 0 Prefoldin subunit WXG100 PF06013.7 EPY51964.1 - 0.034 14.1 11.3 0.76 9.8 1.0 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG AAA_27 PF13514.1 EPY51964.1 - 0.039 11.6 27.1 0.046 11.4 18.8 1.1 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EPY51964.1 - 0.043 12.9 4.8 0.14 11.2 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tenui_PVC2 PF06656.6 EPY51964.1 - 0.048 11.4 1.2 0.054 11.2 0.8 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein Laminin_II PF06009.7 EPY51964.1 - 0.049 13.3 18.4 0.15 11.8 6.0 3.0 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.1 EPY51964.1 - 0.057 11.8 22.5 0.017 13.6 10.3 1.7 1 1 0 1 1 1 0 AAA domain Rho_Binding PF08912.6 EPY51964.1 - 0.06 13.6 2.5 0.06 13.6 1.7 3.9 1 1 3 4 4 4 0 Rho Binding Adeno_PIX PF03955.9 EPY51964.1 - 0.075 13.5 13.7 0.75 10.3 2.3 2.7 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) PilJ PF13675.1 EPY51964.1 - 0.075 13.3 12.9 0.12 12.6 0.7 2.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term NPV_P10 PF05531.7 EPY51964.1 - 0.077 13.2 10.2 0.15 12.3 0.5 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EPY51964.1 - 0.086 12.9 17.4 2.6 8.2 6.0 2.8 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KLRAQ PF10205.4 EPY51964.1 - 0.12 12.4 21.7 0.9 9.6 5.5 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Taxilin PF09728.4 EPY51964.1 - 0.15 11.0 27.0 0.24 10.4 6.3 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Laminin_I PF06008.9 EPY51964.1 - 0.24 10.6 24.5 0.084 12.1 4.4 2.5 1 1 2 3 3 3 0 Laminin Domain I Baculo_PEP_C PF04513.7 EPY51964.1 - 0.24 11.2 3.2 0.69 9.7 0.5 2.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ORF6C PF10552.4 EPY51964.1 - 0.25 11.0 20.2 0.2 11.4 0.5 4.0 1 1 3 4 4 4 0 ORF6C domain ATG16 PF08614.6 EPY51964.1 - 0.25 11.1 31.2 0.39 10.5 10.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.4 EPY51964.1 - 0.31 9.9 26.0 0.1 11.5 14.0 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MamL-1 PF09596.5 EPY51964.1 - 0.32 10.8 5.8 0.35 10.7 0.1 3.0 2 1 1 3 3 3 0 MamL-1 domain CCDC155 PF14662.1 EPY51964.1 - 0.34 10.5 31.2 0.18 11.3 18.8 2.2 1 1 1 2 2 1 0 Coiled-coil region of CCDC155 Spc7 PF08317.6 EPY51964.1 - 0.46 9.1 27.6 0.13 10.8 7.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 EPY51964.1 - 0.54 9.2 34.1 0.13 11.3 9.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 EPY51964.1 - 0.61 10.0 35.2 0.11 12.4 9.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HR1 PF02185.11 EPY51964.1 - 0.64 9.8 24.9 0.83 9.4 1.3 4.2 1 1 3 4 4 4 0 Hr1 repeat Nup54 PF13874.1 EPY51964.1 - 0.68 9.5 22.3 0.39 10.3 3.4 2.6 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Occludin_ELL PF07303.8 EPY51964.1 - 0.69 10.6 18.8 2.3 9.0 0.4 3.6 1 1 2 3 3 3 0 Occludin homology domain EzrA PF06160.7 EPY51964.1 - 0.75 7.9 24.6 4.4 5.3 6.9 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA ERM PF00769.14 EPY51964.1 - 0.94 8.9 38.2 0.17 11.4 16.7 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Lip_prot_lig_C PF10437.4 EPY51964.1 - 0.94 9.1 3.9 0.75 9.5 0.2 2.5 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus TMF_TATA_bd PF12325.3 EPY51964.1 - 0.98 9.1 33.3 0.32 10.7 5.0 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 EPY51964.1 - 0.99 9.3 27.7 0.62 9.9 1.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EPY51964.1 - 1 9.0 31.1 0.69 9.6 7.8 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EPY51964.1 - 1.2 8.9 16.5 0.18 11.5 3.4 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 EPY51964.1 - 1.7 6.9 25.3 0.089 11.1 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) FliD_C PF07195.7 EPY51964.1 - 2 7.6 13.6 5.2e+02 -0.3 9.4 2.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HJURP_C PF12347.3 EPY51964.1 - 2.1 7.9 5.8 0.8 9.3 0.1 2.6 2 2 1 3 3 2 0 Holliday junction regulator protein family C-terminal repeat Streptin-Immun PF11083.3 EPY51964.1 - 2.1 8.3 16.8 2.1 8.3 1.4 3.4 1 1 3 4 4 4 0 Lantibiotic streptin immunity protein DUF641 PF04859.7 EPY51964.1 - 2.9 7.6 19.8 1.2 8.9 3.6 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Cep57_CLD_2 PF14197.1 EPY51964.1 - 2.9 7.8 32.0 3.3 7.7 4.1 3.8 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.15 EPY51964.1 - 3 7.6 34.1 3.6 7.3 2.1 4.2 1 1 2 3 3 3 0 Prefoldin subunit Ax_dynein_light PF10211.4 EPY51964.1 - 3.1 7.6 27.4 0.69 9.7 3.2 2.4 1 1 0 2 2 2 0 Axonemal dynein light chain DUF948 PF06103.6 EPY51964.1 - 3.2 7.6 14.5 0.42 10.4 1.8 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) rRNA_proc-arch PF13234.1 EPY51964.1 - 3.3 6.7 16.9 6.1 5.9 4.4 2.9 1 1 2 3 3 3 0 rRNA-processing arch domain Uds1 PF15456.1 EPY51964.1 - 3.5 7.6 28.0 1.5e+04 -4.8 19.4 2.6 1 1 0 1 1 0 0 Up-regulated During Septation CALCOCO1 PF07888.6 EPY51964.1 - 3.9 5.6 26.2 6.1 5.0 18.2 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.7 EPY51964.1 - 4.1 7.8 20.6 6.3 7.2 3.1 3.6 1 1 3 4 4 3 0 SlyX DUF724 PF05266.9 EPY51964.1 - 4.5 6.8 28.3 6.4 6.3 7.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prominin PF05478.6 EPY51964.1 - 5.3 4.4 9.6 7 4.0 6.6 1.3 1 0 0 1 1 1 0 Prominin Vfa1 PF08432.5 EPY51964.1 - 5.4 6.9 23.1 7.1 6.6 13.3 2.0 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Fib_alpha PF08702.5 EPY51964.1 - 5.6 7.0 16.9 3.7 7.6 5.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.16 EPY51964.1 - 5.6 6.4 12.3 6.4 6.2 0.2 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Phage_GP20 PF06810.6 EPY51964.1 - 6.1 6.2 27.6 3.7 6.9 8.7 2.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 IFT57 PF10498.4 EPY51964.1 - 6.2 5.4 23.4 1.1 7.8 6.8 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4164 PF13747.1 EPY51964.1 - 6.8 6.9 29.2 0.027 14.6 7.8 2.8 1 1 1 2 2 1 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 EPY51964.1 - 7.8 4.2 24.9 0.63 7.8 6.9 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Rootletin PF15035.1 EPY51964.1 - 8.9 6.2 28.7 66 3.4 19.9 2.0 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FliD_N PF02465.13 EPY51964.1 - 9.5 6.6 8.0 17 5.8 0.2 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Spore_III_AB PF09548.5 EPY51964.1 - 9.8 5.8 12.0 11 5.7 1.3 2.5 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF1720 PF08226.6 EPY51965.1 - 1.4e-23 82.7 215.4 3.7e-06 26.9 12.2 9.8 2 2 3 5 5 5 3 Domain of unknown function (DUF1720) EF-hand_4 PF12763.2 EPY51965.1 - 2.3e-09 36.8 0.0 3.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_4 PF12763.2 EPY51966.1 - 1e-14 54.1 0.0 4.1e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EPY51966.1 - 7.2e-10 38.1 0.2 1.8e-09 36.8 0.2 1.8 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EPY51966.1 - 0.00092 19.2 0.1 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPY51966.1 - 0.011 15.5 0.2 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain DUF4518 PF15008.1 EPY51966.1 - 0.04 12.9 0.1 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF904 PF06005.7 EPY51966.1 - 0.062 13.5 0.3 0.062 13.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 EPY51966.1 - 3 7.4 14.2 0.64 9.5 3.3 2.4 1 1 1 2 2 2 0 IncA protein DivIC PF04977.10 EPY51966.1 - 3.4 7.2 6.0 5.2 6.6 1.8 2.8 1 1 1 2 2 2 0 Septum formation initiator eIF2A PF08662.6 EPY51967.1 - 6.6e-41 140.1 5.1 1.1e-39 136.2 0.9 3.1 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EPY51967.1 - 0.002 17.7 0.0 0.0058 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPY51967.1 - 0.0067 16.2 0.2 65 3.6 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat RRM_6 PF14259.1 EPY51967.1 - 0.073 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_3 PF12776.2 EPY51967.1 - 0.095 13.3 5.0 6.3 7.4 0.2 3.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Kinesin PF00225.18 EPY51968.1 - 1.8e-107 358.9 1.5 1.8e-107 358.9 1.0 3.2 3 0 0 3 3 3 1 Kinesin motor domain Ribosomal_S28e PF01200.13 EPY51969.1 - 3.4e-34 116.4 2.0 3.6e-34 116.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EPY51970.1 - 7.5e-56 188.2 0.1 1.3e-55 187.4 0.1 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EPY51970.1 - 2.7e-26 91.3 0.3 4.6e-26 90.5 0.2 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EPY51970.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like Red1 PF07964.6 EPY51971.1 - 2e-19 69.2 0.3 2e-19 69.2 0.2 3.3 2 1 0 2 2 2 1 Rec10 / Red1 bZIP_2 PF07716.10 EPY51972.1 - 2e-11 43.5 14.0 3.7e-11 42.6 9.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EPY51972.1 - 4.9e-07 29.5 10.4 1e-06 28.5 7.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 EPY51972.1 - 9.1e-05 22.3 0.6 0.0002 21.2 0.4 1.5 1 0 0 1 1 1 1 Haemolysin XhlA TSC22 PF01166.13 EPY51972.1 - 0.031 14.2 0.5 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 EPY51972.1 - 0.039 14.2 3.1 0.039 14.2 2.1 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor PEARLI-4 PF05278.7 EPY51972.1 - 0.055 12.8 3.6 0.11 11.8 2.5 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Seryl_tRNA_N PF02403.17 EPY51972.1 - 0.84 9.6 8.1 0.31 11.0 3.6 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ydc2-catalyt PF09159.5 EPY51973.1 - 3e-35 122.0 2.8 1.6e-31 109.8 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EPY51973.1 - 6e-06 26.1 0.9 0.0048 16.7 0.0 3.2 2 2 0 2 2 2 2 Poxvirus A22 protein SAP PF02037.22 EPY51973.1 - 0.00051 19.4 0.0 0.00096 18.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain Terminase_6 PF03237.10 EPY51973.1 - 0.017 13.8 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family adh_short_C2 PF13561.1 EPY51973.1 - 0.038 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase RRM_1 PF00076.17 EPY51974.1 - 1.7e-19 69.1 0.0 2.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY51974.1 - 1e-14 54.2 0.0 1.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY51974.1 - 4.6e-10 39.1 0.0 7.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4364 PF14277.1 EPY51974.1 - 0.17 11.4 0.0 0.53 9.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) MS_channel PF00924.13 EPY51975.1 - 9.4e-33 113.2 0.8 2e-32 112.2 0.6 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EPY51975.1 - 0.045 13.0 0.1 0.11 11.8 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EPY51975.1 - 0.074 12.9 0.2 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain Ribosomal_S8e PF01201.17 EPY51976.1 - 8e-50 168.3 1.6 9.3e-50 168.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EPY51976.1 - 0.071 13.3 0.2 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Small acidic protein family Thioredoxin_7 PF13899.1 EPY51977.1 - 7.4e-16 57.9 0.0 1.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EPY51977.1 - 1.3e-14 54.0 0.0 2.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EPY51977.1 - 5e-13 48.3 0.0 8.9e-13 47.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.1 EPY51977.1 - 0.012 15.8 0.0 0.045 13.9 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredox_DsbH PF03190.10 EPY51977.1 - 0.046 13.4 0.1 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Pkinase PF00069.20 EPY51978.1 - 9.3e-69 231.4 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51978.1 - 1.7e-45 155.1 0.0 2.7e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY51978.1 - 1.4e-06 27.5 0.1 0.00061 18.8 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPY51978.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPY51978.1 - 0.14 11.8 0.0 0.92 9.1 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family ATP-synt_C PF00137.16 EPY51979.1 - 2.5e-26 91.3 27.0 3.4e-15 55.6 7.1 2.3 2 0 0 2 2 2 2 ATP synthase subunit C PTS_2-RNA PF01885.11 EPY51980.1 - 1.2e-37 128.9 0.8 2e-21 76.1 0.0 2.2 1 1 1 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family Yae1_N PF09811.4 EPY51980.1 - 1.6e-07 30.7 4.2 3e-07 29.8 2.9 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal KH_1 PF00013.24 EPY51981.1 - 0.001 18.6 1.4 0.0014 18.2 0.2 1.7 2 0 0 2 2 2 1 KH domain DUF4164 PF13747.1 EPY51982.1 - 0.0063 16.6 0.2 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) CSF-1 PF05337.6 EPY51982.1 - 0.0099 15.2 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Macrophage colony stimulating factor-1 (CSF-1) Exonuc_VII_S PF02609.11 EPY51982.1 - 0.055 13.2 1.4 0.7 9.7 0.6 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit Z1 PF10593.4 EPY51982.1 - 0.15 11.2 1.9 4.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Z1 domain Cluap1 PF10234.4 EPY51982.1 - 0.19 10.9 5.5 0.22 10.6 0.5 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4024 PF13216.1 EPY51982.1 - 0.21 11.4 0.8 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) DUF939_C PF11728.3 EPY51982.1 - 0.22 11.2 4.7 0.14 11.9 1.3 1.9 1 1 1 2 2 2 0 DUF939 C-terminal domain 4HB_MCP_1 PF12729.2 EPY51982.1 - 1.5 8.1 9.3 0.97 8.7 0.2 2.3 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction Fzo_mitofusin PF04799.8 EPY51982.1 - 1.8 7.9 5.0 0.5 9.7 0.6 2.0 1 1 0 2 2 2 0 fzo-like conserved region KLRAQ PF10205.4 EPY51982.1 - 1.9 8.5 6.9 1.7 8.7 1.4 2.7 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein BLOC1_2 PF10046.4 EPY51982.1 - 3.5 7.8 8.9 10 6.3 2.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3347 PF11827.3 EPY51982.1 - 3.5 7.5 9.5 2.2 8.2 2.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3347) DivIVA PF05103.8 EPY51982.1 - 5 7.1 7.7 7.6 6.5 0.2 2.8 1 1 1 3 3 3 0 DivIVA protein Cep57_CLD_2 PF14197.1 EPY51982.1 - 6.8 6.7 9.7 1.1 9.2 0.2 3.4 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF1640 PF07798.6 EPY51983.1 - 7.7e-53 179.1 5.2 8.8e-53 178.9 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FlaC_arch PF05377.6 EPY51983.1 - 0.013 15.3 0.3 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HeLo PF14479.1 EPY51983.1 - 0.017 14.8 3.0 0.023 14.4 2.1 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation Pepsin-I3 PF06394.8 EPY51983.1 - 0.25 11.0 3.9 1.1 9.0 0.0 2.6 2 1 1 3 3 3 0 Pepsin inhibitor-3-like repeated domain Phage_glycop_gL PF11108.3 EPY51983.1 - 0.36 10.8 3.0 0.93 9.4 0.3 2.6 1 1 2 3 3 3 0 Viral glycoprotein L Baculo_PEP_C PF04513.7 EPY51983.1 - 0.4 10.4 4.5 1.2 8.9 3.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 EPY51983.1 - 0.42 8.0 6.6 0.53 7.7 4.6 1.1 1 0 0 1 1 1 0 Prominin XhlA PF10779.4 EPY51983.1 - 0.89 9.5 4.1 10 6.1 1.9 2.6 1 1 1 2 2 2 0 Haemolysin XhlA Phage_GP20 PF06810.6 EPY51983.1 - 0.9 8.9 7.1 1.5 8.2 3.1 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 GCN5L1 PF06320.8 EPY51983.1 - 1.4 8.7 6.0 2.9 7.7 0.1 2.4 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) RNB PF00773.14 EPY51985.1 - 1.3e-97 326.9 0.0 5.7e-97 324.8 0.0 2.1 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 EPY51985.1 - 0.0078 15.6 0.1 0.022 14.2 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease B OB domain Nol1_Nop2_Fmu PF01189.12 EPY51986.1 - 2.2e-28 99.4 0.1 4e-28 98.5 0.1 1.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EPY51986.1 - 9e-05 22.0 0.1 0.00031 20.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY51986.1 - 0.0002 21.8 0.0 0.00041 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPY51986.1 - 0.00054 19.0 0.1 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 EPY51986.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cornichon PF03311.9 EPY51987.1 - 1.3e-41 141.6 12.0 1.5e-41 141.5 8.3 1.0 1 0 0 1 1 1 1 Cornichon protein PEN-2 PF10251.4 EPY51987.1 - 0.23 11.7 4.3 14 5.9 2.2 2.1 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF1201 PF06716.6 EPY51987.1 - 2.6 7.9 7.2 0.26 11.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) DUF2340 PF10209.4 EPY51989.1 - 8.7e-49 164.7 1.6 9.7e-49 164.5 1.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) ubiquitin PF00240.18 EPY51989.1 - 0.0078 15.5 1.4 2 7.8 0.1 2.4 1 1 1 2 2 2 2 Ubiquitin family DUF739 PF05339.6 EPY51989.1 - 0.098 12.4 0.3 0.36 10.6 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF739) Rad60-SLD PF11976.3 EPY51989.1 - 0.16 11.7 0.7 0.62 9.7 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like ABC_tran PF00005.22 EPY51990.1 - 3.6e-45 153.6 0.0 1.8e-22 80.1 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPY51990.1 - 6.9e-15 55.7 1.5 0.0016 18.4 0.0 4.3 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EPY51990.1 - 6.6e-12 45.1 0.2 0.05 12.8 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPY51990.1 - 1.8e-09 36.9 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EPY51990.1 - 3.3e-08 34.0 1.8 0.0089 16.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EPY51990.1 - 6.3e-08 33.4 0.0 0.0082 16.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPY51990.1 - 2.5e-07 30.9 0.0 0.024 14.7 0.0 4.0 4 1 0 4 4 3 2 AAA domain AAA_10 PF12846.2 EPY51990.1 - 6.3e-07 29.1 0.0 0.05 13.0 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_15 PF13175.1 EPY51990.1 - 6.6e-07 28.7 0.3 0.14 11.1 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPY51990.1 - 1.1e-06 28.5 0.0 0.07 13.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EPY51990.1 - 2.3e-06 26.9 0.0 0.0041 16.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EPY51990.1 - 2.9e-06 27.7 0.0 0.08 13.4 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EPY51990.1 - 3.2e-06 26.9 0.6 0.041 13.5 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPY51990.1 - 1.1e-05 25.3 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPY51990.1 - 2.7e-05 24.4 0.0 0.17 12.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EPY51990.1 - 3e-05 23.9 0.3 0.037 13.8 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EPY51990.1 - 7.3e-05 22.5 0.0 0.08 12.6 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EPY51990.1 - 8e-05 22.6 1.0 0.2 11.6 0.1 3.7 3 1 0 3 3 3 1 AAA ATPase domain Dynamin_N PF00350.18 EPY51990.1 - 8.2e-05 22.4 0.0 0.017 14.9 0.0 2.6 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.1 EPY51990.1 - 0.0001 22.1 0.0 0.26 11.2 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EPY51990.1 - 0.00011 22.1 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EPY51990.1 - 0.00012 22.2 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 EPY51990.1 - 0.00016 21.8 0.1 0.94 9.6 0.0 3.7 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 EPY51990.1 - 0.00018 20.3 0.1 0.54 8.9 0.0 2.4 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 EPY51990.1 - 0.00024 20.7 0.0 0.39 10.3 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_14 PF13173.1 EPY51990.1 - 0.00043 20.1 0.0 1.5 8.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain MutS_V PF00488.16 EPY51990.1 - 0.001 18.5 0.0 0.93 8.8 0.0 2.4 2 0 0 2 2 2 2 MutS domain V HEAT_EZ PF13513.1 EPY51990.1 - 0.0013 19.1 0.6 7.2 7.2 0.1 4.4 4 0 0 4 4 3 0 HEAT-like repeat cobW PF02492.14 EPY51990.1 - 0.002 17.6 0.3 0.56 9.6 0.0 3.0 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EPY51990.1 - 0.0029 17.0 0.0 4.5 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 EPY51990.1 - 0.0061 15.4 0.1 3.9 6.3 0.0 2.9 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_13 PF13166.1 EPY51990.1 - 0.009 14.5 0.0 2.8 6.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EPY51990.1 - 0.0092 15.5 0.0 7.1 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPY51990.1 - 0.011 15.4 0.1 2.6 7.8 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EPY51990.1 - 0.013 14.9 0.6 6.5 6.1 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EPY51990.1 - 0.019 14.4 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EPY51990.1 - 0.022 13.8 0.1 14 4.6 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin ATP_bind_1 PF03029.12 EPY51990.1 - 0.023 14.2 0.3 8.8 5.7 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 EPY51990.1 - 0.032 13.1 0.0 6.5 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EPY51990.1 - 0.033 13.3 0.2 0.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EPY51990.1 - 0.071 12.8 0.6 14 5.3 0.0 2.7 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.10 EPY51990.1 - 0.073 11.7 0.0 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein MMS19_N PF14500.1 EPY51990.1 - 0.083 12.1 0.1 0.7 9.1 0.0 2.3 1 1 2 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 EPY51990.1 - 0.094 12.8 0.2 1.9 8.8 0.1 3.4 4 0 0 4 4 1 0 HEAT repeat Septin PF00735.13 EPY51990.1 - 0.1 11.6 0.1 5.4 5.9 0.0 2.6 3 0 0 3 3 3 0 Septin Microtub_assoc PF07989.6 EPY51991.1 - 1.5e-23 82.3 4.1 1.5e-23 82.3 2.8 10.0 11 3 2 13 13 13 1 Microtubule associated Mto2_bdg PF12808.2 EPY51991.1 - 9e-17 60.9 8.6 9e-17 60.9 6.0 6.4 8 0 0 8 8 8 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Myosin_tail_1 PF01576.14 EPY51991.1 - 0.0002 19.2 51.1 0.0002 19.2 35.4 5.3 3 2 1 4 4 4 2 Myosin tail Reo_sigmaC PF04582.7 EPY51991.1 - 0.0082 15.3 1.0 0.0082 15.3 0.7 6.3 2 2 5 7 7 7 2 Reovirus sigma C capsid protein FGase PF05013.7 EPY51991.1 - 0.021 14.7 0.3 0.92 9.3 0.0 2.4 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase DUF2937 PF11157.3 EPY51991.1 - 0.14 11.4 21.0 3.3 7.0 0.7 5.7 3 1 1 5 5 5 0 Protein of unknown function (DUF2937) AAA_13 PF13166.1 EPY51991.1 - 0.47 8.8 96.9 0.35 9.2 22.6 4.5 1 1 3 4 4 4 0 AAA domain Pkinase PF00069.20 EPY51992.1 - 2.1e-59 200.7 0.0 3.5e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY51992.1 - 4.2e-29 101.4 0.0 7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPY51992.1 - 9e-05 22.9 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPY51992.1 - 0.00044 19.3 0.0 0.001 18.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DASH_Hsk3 PF08227.6 EPY51993.1 - 3.4e-16 59.1 4.4 5.4e-16 58.5 3.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DASH_Dam1 PF08653.5 EPY51993.1 - 0.015 15.0 0.2 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 GvpK PF05121.7 EPY51993.1 - 0.1 12.4 1.2 0.58 10.0 0.2 1.9 1 1 1 2 2 2 0 Gas vesicle protein K PAP1 PF08601.5 EPY51993.1 - 0.22 11.1 5.6 0.26 10.9 3.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 GATA PF00320.22 EPY51994.1 - 4.8e-16 57.8 1.9 9.6e-16 56.8 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EPY51994.1 - 3.6e-11 42.4 3.3 6.6e-11 41.5 2.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ApbA PF02558.11 EPY51995.1 - 6.3e-24 84.1 0.0 9.4e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPY51995.1 - 7.1e-18 64.8 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF3818 PF12825.2 EPY51996.1 - 7.1e-64 215.6 2.2 2.3e-63 213.9 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EPY51996.1 - 3e-27 94.8 0.0 7.1e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 PX-associated PAP_assoc PF03828.14 EPY51997.1 - 2.6e-12 46.4 0.0 5.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF3126 PF11324.3 EPY51997.1 - 0.043 13.4 0.1 0.46 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3126) PX PF00787.19 EPY51997.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 PX domain TRP PF06011.7 EPY51998.1 - 2e-67 227.6 27.7 3e-67 227.1 19.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPY51998.1 - 5.4e-30 104.2 0.1 9.4e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 ML-like domain Acetyltransf_1 PF00583.19 EPY51999.1 - 3e-10 40.0 0.0 4.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPY51999.1 - 2.7e-09 37.1 0.0 3.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPY51999.1 - 4.7e-08 33.0 0.0 6.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EPY51999.1 - 0.0036 16.8 0.0 0.0041 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPY51999.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Wbp11 PF09429.5 EPY52000.1 - 1.7e-18 66.3 10.8 1.7e-18 66.3 7.5 3.3 3 1 0 3 3 3 1 WW domain binding protein 11 NpwBP PF12622.2 EPY52000.1 - 8.7e-13 48.5 7.8 8.7e-13 48.5 5.4 2.8 2 0 0 2 2 2 1 mRNA biogenesis factor AdoMet_MTase PF07757.8 EPY52001.1 - 5.4e-50 168.2 0.2 9.5e-50 167.4 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 EPY52001.1 - 2e-05 24.3 0.0 7.7e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EPY52001.1 - 0.034 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.1 EPY52001.1 - 0.051 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain L51_S25_CI-B8 PF05047.11 EPY52002.1 - 1e-07 31.5 0.1 1.6e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RNA_pol_A_bac PF01000.21 EPY52003.1 - 1.5e-31 108.8 0.0 3.6e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPY52003.1 - 2.5e-15 55.3 0.0 3.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EPY52003.1 - 0.15 11.6 0.0 0.41 10.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF22 Chorismate_bind PF00425.13 EPY52004.1 - 2.7e-90 302.1 0.0 3.5e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EPY52004.1 - 3.9e-27 94.9 0.1 1.3e-24 86.7 0.0 3.1 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region COX6B PF02297.12 EPY52005.1 - 4.6e-20 71.4 3.7 5.6e-20 71.1 2.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EPY52005.1 - 0.034 14.0 0.3 0.034 14.0 0.2 1.6 2 0 0 2 2 2 0 CHCH domain UCR_hinge PF02320.11 EPY52005.1 - 0.16 11.9 2.1 0.27 11.1 0.3 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 EPY52005.1 - 1.5 8.7 4.4 2.5 8.0 0.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) WLM PF08325.5 EPY52006.1 - 1.1e-39 136.2 4.9 7.2e-39 133.5 3.4 2.0 1 1 0 1 1 1 1 WLM domain ubiquitin PF00240.18 EPY52006.1 - 4.6e-07 29.1 0.9 8.4e-07 28.2 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF45 PF01863.12 EPY52006.1 - 0.00047 19.9 4.0 0.0046 16.7 2.6 2.6 1 1 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 EPY52006.1 - 0.015 15.3 0.5 0.044 13.8 0.2 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily SprT-like PF10263.4 EPY52006.1 - 0.048 13.3 0.6 0.076 12.6 0.4 1.3 1 0 0 1 1 1 0 SprT-like family Proteasome PF00227.21 EPY52007.1 - 7e-59 198.3 0.1 9.7e-59 197.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPY52007.1 - 2e-10 39.8 0.3 4.9e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ApoO PF09769.4 EPY52008.1 - 2.9e-23 82.3 0.3 1.1e-21 77.1 0.0 2.0 1 1 1 2 2 2 1 Apolipoprotein O Syntaxin_2 PF14523.1 EPY52008.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Syntaxin-like protein Ca_hom_mod PF14798.1 EPY52008.1 - 0.0063 15.5 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF2537 PF10801.3 EPY52008.1 - 0.13 12.3 0.3 0.21 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) Bromodomain PF00439.20 EPY52009.1 - 6.4e-48 160.6 0.1 7.1e-23 80.3 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 EPY52010.1 - 3.5e-06 26.8 0.0 4.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Hid1 PF12722.2 EPY52010.1 - 4.2 4.9 6.4 4.8 4.7 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EF1_GNE PF00736.14 EPY52011.1 - 2e-29 101.0 0.3 3.6e-29 100.2 0.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EPY52011.1 - 4.6e-12 45.8 4.2 1.5e-11 44.2 2.9 2.0 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EPY52011.1 - 0.0011 19.4 0.1 0.0035 17.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPY52011.1 - 0.002 17.9 2.0 0.045 13.6 0.5 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPY52011.1 - 0.42 10.6 1.7 0.72 9.8 0.0 2.2 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Rox3 PF08633.5 EPY52012.1 - 9.5e-18 65.2 0.0 1e-17 65.0 0.0 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Glutaredoxin PF00462.19 EPY52013.1 - 1.5e-11 44.0 0.0 2.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DAO PF01266.19 EPY52014.1 - 5.6e-19 68.2 0.0 1.1e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPY52014.1 - 0.016 15.2 0.4 0.044 13.8 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPY52014.1 - 0.033 14.5 0.2 0.07 13.5 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPY52014.1 - 0.053 12.6 0.1 0.092 11.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Fe_hyd_lg_C PF02906.9 EPY52015.1 - 3.6e-70 236.4 0.0 4e-69 233.0 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Pkinase PF00069.20 EPY52016.1 - 2.6e-58 197.2 0.0 3e-37 128.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52016.1 - 4.2e-26 91.5 0.1 6.9e-21 74.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EPY52016.1 - 3.4e-05 22.9 0.0 0.001 18.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PAS_9 PF13426.1 EPY52016.1 - 0.0012 19.1 0.0 0.0039 17.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain APH PF01636.18 EPY52016.1 - 0.0019 17.9 0.0 0.96 9.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPY52016.1 - 0.018 13.9 0.1 2.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Seadornavirus VP7 Phage_int_SAM_4 PF13495.1 EPY52016.1 - 0.2 11.9 1.6 1.9 8.8 0.5 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3818 PF12825.2 EPY52018.1 - 1.1e-101 339.9 8.4 1.1e-101 339.9 5.8 2.0 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EPY52018.1 - 4.3e-28 97.6 0.5 1.4e-27 96.0 0.4 2.0 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EPY52018.1 - 2.6e-19 69.0 1.0 9e-19 67.3 0.7 2.0 1 0 0 1 1 1 1 PX domain Lum_binding PF00677.12 EPY52019.1 - 3.7e-46 154.9 2.5 7.5e-25 86.6 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain TRL PF13146.1 EPY52019.1 - 0.066 13.2 0.5 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 TRL-like protein family ERO1 PF04137.10 EPY52020.1 - 1.6e-123 412.2 0.2 2e-123 411.9 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fer4_18 PF13746.1 EPY52020.1 - 0.053 13.9 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain PIG-F PF06699.6 EPY52021.1 - 4.3e-43 147.4 14.9 7.7e-43 146.6 10.3 1.4 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F adh_short PF00106.20 EPY52021.1 - 2.3e-08 34.1 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EPY52021.1 - 0.026 13.6 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3336 PF11815.3 EPY52022.1 - 2e-33 114.9 0.3 3.1e-33 114.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPY52022.1 - 1.7e-11 44.4 0.0 2.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase RasGEF PF00617.14 EPY52023.1 - 7.4e-54 182.3 4.3 1.7e-53 181.1 3.0 1.6 1 0 0 1 1 1 1 RasGEF domain SH3_1 PF00018.23 EPY52023.1 - 2.3e-10 39.6 0.0 4.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPY52023.1 - 1.9e-08 33.7 0.0 3.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RasGEF_N PF00618.15 EPY52023.1 - 4.4e-08 33.1 0.7 4.4e-08 33.1 0.5 3.5 3 2 1 4 4 4 1 RasGEF N-terminal motif SH3_2 PF07653.12 EPY52023.1 - 1.6e-05 24.2 0.0 3.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kinetochor_Ybp2 PF08568.5 EPY52024.1 - 3e-43 148.0 18.3 2.3e-23 82.3 1.1 2.0 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Mito_carr PF00153.22 EPY52025.1 - 5e-69 228.0 1.0 1.6e-25 88.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 EPY52025.1 - 0.00091 19.5 0.1 1.4 9.3 0.2 2.5 2 0 0 2 2 2 2 YtxH-like protein DUF2420 PF10336.4 EPY52026.1 - 3e-24 84.7 0.8 6.5e-24 83.7 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) CDP-OH_P_transf PF01066.16 EPY52027.1 - 2.1e-13 50.3 4.7 2.1e-13 50.3 3.3 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase G-patch PF01585.18 EPY52028.1 - 1.1e-11 44.3 2.6 1.1e-11 44.3 1.8 2.1 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EPY52028.1 - 2 8.3 5.4 0.41 10.5 0.7 2.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site HIT PF01230.18 EPY52029.1 - 1.5e-23 83.1 0.0 2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPY52029.1 - 6.4e-13 48.9 0.0 8.4e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPY52029.1 - 0.0012 18.5 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 EPY52029.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 60KD_IMP PF02096.15 EPY52030.1 - 1.6e-29 102.9 1.1 2e-29 102.6 0.8 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein ADH_zinc_N PF00107.21 EPY52031.1 - 6.7e-23 80.6 0.0 1.1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPY52031.1 - 3.8e-12 45.9 0.1 1.8e-11 43.7 0.0 2.2 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPY52031.1 - 1.4e-11 45.4 0.0 2.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EPY52031.1 - 0.024 14.5 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Ist1 PF03398.9 EPY52032.1 - 1.2e-32 112.6 0.1 1.6e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DEAD PF00270.24 EPY52033.1 - 1.5e-41 141.7 0.0 2.7e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY52033.1 - 1.2e-20 73.1 0.0 2.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY52033.1 - 5.5e-13 49.1 0.5 4.4e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPY52033.1 - 0.00035 19.4 0.1 0.0026 16.5 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EPY52033.1 - 0.03 14.4 0.9 0.14 12.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain Transthyretin PF00576.16 EPY52034.1 - 3.5e-36 123.5 0.2 3.9e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Big_1 PF02369.11 EPY52034.1 - 0.0012 18.7 0.2 0.0016 18.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) NUP PF06516.6 EPY52035.1 - 6.5e-105 350.4 1.6 7.5e-105 350.2 1.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) PNP_UDP_1 PF01048.15 EPY52035.1 - 0.0044 16.0 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily GDPD PF03009.12 EPY52036.1 - 2.3e-80 269.7 0.0 5.2e-80 268.6 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EPY52036.1 - 2e-24 85.7 0.9 3.3e-12 46.5 0.5 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPY52036.1 - 7.5e-20 69.6 4.0 1.1e-05 24.9 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EPY52036.1 - 1.2e-15 57.5 0.7 9.9e-05 22.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPY52036.1 - 3.4e-14 52.5 1.0 8.9e-06 25.7 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPY52036.1 - 4.7e-14 51.1 0.4 0.29 11.4 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat SPX PF03105.14 EPY52036.1 - 5e-11 42.8 2.3 3.6e-05 23.6 0.1 3.0 2 1 1 3 3 3 2 SPX domain ERCC4 PF02732.10 EPY52037.1 - 0.00049 19.8 1.1 0.0009 19.0 0.1 2.0 3 0 0 3 3 3 1 ERCC4 domain Glu_synthase PF01645.12 EPY52038.1 - 5.1e-162 538.9 0.1 6.2e-161 535.3 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EPY52038.1 - 7.9e-136 452.4 0.0 1.1e-135 452.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EPY52038.1 - 4.9e-114 380.4 0.0 1.1e-113 379.2 0.0 1.6 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EPY52038.1 - 8.3e-67 224.1 1.0 8.3e-67 224.1 0.7 1.8 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 EPY52038.1 - 1e-22 79.8 0.1 2.6e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EPY52038.1 - 6.5e-22 78.3 0.0 2.9e-19 69.7 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPY52038.1 - 2.9e-12 47.0 0.2 5.8e-06 26.5 0.1 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPY52038.1 - 3.8e-08 33.2 0.0 1.4e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPY52038.1 - 6.9e-06 26.3 0.2 0.00023 21.4 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPY52038.1 - 1.3e-05 24.4 0.1 0.00022 20.4 0.0 2.7 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EPY52038.1 - 2.5e-05 23.3 0.2 0.00082 18.3 0.1 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPY52038.1 - 3e-05 23.2 0.0 6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EPY52038.1 - 8.9e-05 21.1 0.9 0.00013 20.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EPY52038.1 - 0.00022 20.1 0.1 0.00091 18.1 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EPY52038.1 - 0.0014 17.7 0.0 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPY52038.1 - 0.0031 16.6 0.1 0.006 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EPY52038.1 - 0.0047 16.5 0.0 0.056 12.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.13 EPY52038.1 - 0.012 14.5 2.0 0.05 12.4 1.6 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DJ-1_PfpI PF01965.19 EPY52038.1 - 0.016 14.6 0.1 4.7 6.6 0.0 3.2 2 1 1 3 3 3 0 DJ-1/PfpI family NAD_binding_7 PF13241.1 EPY52038.1 - 0.029 14.6 0.3 2.7 8.2 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EPY52038.1 - 0.05 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 EPY52038.1 - 0.068 12.5 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain FMO-like PF00743.14 EPY52038.1 - 0.069 11.3 0.0 0.9 7.6 0.0 2.3 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.9 EPY52038.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 EPY52038.1 - 0.17 11.6 0.1 2.8 7.7 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EPY52038.1 - 1.4 7.6 5.1 0.17 10.6 0.2 1.9 2 1 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 EPY52039.1 - 5.5e-29 100.9 48.6 1.3e-23 83.3 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY52039.1 - 2e-17 62.9 23.4 2.9e-16 59.0 16.2 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter PMT PF02366.13 EPY52041.1 - 1.3e-72 244.0 24.6 1.3e-72 244.0 17.0 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPY52041.1 - 1.2e-19 70.6 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 MIR domain RNA_pol_Rpb4 PF03874.11 EPY52043.1 - 1.5e-22 79.7 4.5 1.7e-22 79.6 3.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 COesterase PF00135.23 EPY52043.1 - 0.022 13.4 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family LigA PF07746.6 EPY52043.1 - 0.43 10.6 7.4 2.2 8.3 0.5 2.9 2 1 1 3 3 3 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit Ribosomal_S6e PF01092.14 EPY52044.1 - 2.3e-64 214.7 0.1 4.9e-64 213.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Orbi_VP6 PF01516.11 EPY52045.1 - 0.068 12.2 0.7 0.079 12.0 0.5 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 Glyco_hydro_47 PF01532.15 EPY52046.1 - 2.1e-150 501.3 4.0 2.4e-150 501.1 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AnfG_VnfG PF03139.10 EPY52046.1 - 0.0065 16.2 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Vanadium/alternative nitrogenase delta subunit PRA1 PF03208.14 EPY52047.1 - 3.4e-08 32.9 5.4 4.2e-08 32.6 3.8 1.1 1 0 0 1 1 1 1 PRA1 family protein YwiC PF14256.1 EPY52047.1 - 0.32 11.1 6.1 0.27 11.3 3.4 1.5 1 1 0 1 1 1 0 YwiC-like protein DnaJ PF00226.26 EPY52048.1 - 5.3e-16 58.1 0.2 9.8e-16 57.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Prenyltrans PF00432.16 EPY52049.1 - 6.3e-33 112.0 2.9 1e-10 40.9 0.0 4.7 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPY52049.1 - 1.1e-22 80.5 2.2 8.6e-09 35.8 0.3 3.1 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPY52049.1 - 2.7e-05 24.1 0.0 0.18 11.8 0.0 3.3 2 2 1 3 3 3 2 Prenyltransferase-like WD40 PF00400.27 EPY52050.1 - 4.2e-24 83.5 9.6 4.6e-06 26.2 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Asp PF00026.18 EPY52051.1 - 3.2e-69 233.6 4.5 4.1e-69 233.2 3.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPY52051.1 - 3e-10 40.2 0.0 2.1e-09 37.5 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPY52051.1 - 3.3e-09 36.4 0.4 3.3e-06 26.7 0.0 3.6 3 1 0 3 3 3 2 Xylanase inhibitor C-terminal LNS2 PF08235.8 EPY52051.1 - 0.058 12.9 0.2 3.2 7.2 0.0 3.4 4 1 0 4 4 4 0 LNS2 (Lipin/Ned1/Smp2) Asp_protease_2 PF13650.1 EPY52051.1 - 0.065 13.7 0.1 9 6.8 0.0 3.2 2 1 1 3 3 3 0 Aspartyl protease HhH-GPD PF00730.20 EPY52052.1 - 1.8e-17 63.5 0.0 5.4e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EPY52052.1 - 2e-14 52.9 0.1 4.9e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain EndIII_4Fe-2S PF10576.4 EPY52052.1 - 2.5e-06 27.4 2.5 6.2e-06 26.1 1.8 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 EPY52052.1 - 6.1e-05 22.4 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF1767 PF08585.7 EPY52053.1 - 2.5e-14 53.3 0.1 4.8e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Ribosomal_L18ae PF01775.12 EPY52054.1 - 5.3e-55 184.6 0.4 6.5e-55 184.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Clathrin PF00637.15 EPY52055.1 - 7.9e-198 647.9 49.4 4e-33 114.0 1.2 7.8 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EPY52055.1 - 3.1e-30 103.8 1.3 2e-29 101.2 0.5 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EPY52055.1 - 3.5e-25 86.5 5.4 0.00011 22.2 0.0 6.8 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin-link PF09268.5 EPY52055.1 - 8.7e-11 40.6 0.3 2.6e-10 39.1 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 EPY52055.1 - 3.5e-08 32.7 4.5 0.029 13.1 0.0 5.2 4 1 1 6 6 6 3 Coatomer WD associated region TPR_7 PF13176.1 EPY52055.1 - 6e-05 22.5 3.5 2.2 8.2 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52055.1 - 0.074 13.0 7.7 4.2 7.5 0.0 6.6 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52055.1 - 0.71 10.6 13.7 1.7e+02 3.2 0.1 8.4 8 1 1 9 9 9 0 Tetratricopeptide repeat WBS_methylT PF12589.3 EPY52056.1 - 1.5e-14 54.2 6.0 2.6e-14 53.4 4.1 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EPY52056.1 - 2.1e-10 40.9 0.0 8.1e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY52056.1 - 5.9e-08 32.5 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY52056.1 - 2.3e-07 30.5 0.0 3.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY52056.1 - 5e-05 23.6 0.1 0.0011 19.4 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY52056.1 - 6.2e-05 23.3 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPY52056.1 - 8.2e-05 21.8 0.0 0.00023 20.3 0.0 1.6 1 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EPY52056.1 - 0.00044 20.8 0.0 0.0011 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY52056.1 - 0.0011 19.0 0.0 0.0029 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPY52056.1 - 0.023 13.8 0.3 0.052 12.6 0.0 1.9 2 1 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EPY52056.1 - 0.026 14.0 0.0 0.093 12.2 0.0 1.9 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_L5_C PF00673.16 EPY52057.1 - 3.1e-23 81.3 0.0 4.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPY52057.1 - 4e-20 71.3 0.1 1e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EPY52058.1 - 1.2e-18 66.3 0.2 1.5e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain RhoGAP PF00620.22 EPY52059.1 - 3e-39 134.0 0.5 1.5e-38 131.7 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EPY52059.1 - 4.4e-05 23.6 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 PH domain ArfGap PF01412.13 EPY52060.1 - 1.7e-29 101.9 0.0 4.4e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EPY52060.1 - 1.2e-10 41.5 2.0 2e-10 40.7 0.5 2.2 2 0 0 2 2 2 1 PH domain DUF3614 PF12267.3 EPY52060.1 - 2.4 8.4 6.0 10 6.3 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) CN_hydrolase PF00795.17 EPY52061.1 - 7.5e-32 110.1 0.0 1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_6 PF13964.1 EPY52061.1 - 0.064 13.4 0.0 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Mur_ligase_C PF02875.16 EPY52061.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain XRN_N PF03159.13 EPY52062.1 - 1.6e-108 361.6 0.2 4.1e-108 360.2 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF1748 PF08520.5 EPY52063.1 - 1.9e-27 94.6 0.1 2.1e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Nsp1_C PF05064.8 EPY52064.1 - 1.4e-33 114.9 0.2 3.3e-33 113.8 0.2 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EPY52064.1 - 0.0027 17.9 159.8 0.021 15.0 27.3 4.4 1 1 3 4 4 4 3 Nucleoporin FG repeat region ALIX_LYPXL_bnd PF13949.1 EPY52064.1 - 0.0033 16.4 1.0 0.021 13.8 0.7 1.9 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV ubiquitin PF00240.18 EPY52065.1 - 2.9e-18 65.0 0.1 4.6e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EPY52065.1 - 4e-08 32.8 0.0 8.7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EPY52065.1 - 1.1e-07 31.4 0.1 1.8e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPY52065.1 - 0.00012 22.1 0.1 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPY52065.1 - 0.043 13.6 0.0 0.093 12.6 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPY52065.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Ank_2 PF12796.2 EPY52066.1 - 6.7e-05 23.1 0.6 0.00013 22.2 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Methyltransf_16 PF10294.4 EPY52066.1 - 0.0039 16.6 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 EPY52066.1 - 0.029 14.8 0.0 0.086 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPY52066.1 - 0.067 13.7 0.0 0.31 11.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 EPY52067.1 - 6.1e-26 91.3 1.1 7.3e-26 91.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY52067.1 - 5.1e-25 88.6 0.0 6.2e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY52067.1 - 4.2e-10 39.5 0.3 5.8e-10 39.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPY52067.1 - 0.01 15.6 1.5 0.019 14.7 1.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EPY52067.1 - 0.014 14.8 0.3 0.019 14.3 0.2 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EPY52067.1 - 0.015 15.7 0.1 0.033 14.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HATPase_c PF02518.21 EPY52067.1 - 0.032 13.9 0.2 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sof1 PF04158.9 EPY52067.1 - 0.043 13.8 0.3 0.083 12.9 0.2 1.4 1 0 0 1 1 1 0 Sof1-like domain NAD_binding_10 PF13460.1 EPY52067.1 - 0.043 13.8 0.3 0.09 12.7 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EPY52067.1 - 0.057 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.10 EPY52067.1 - 0.058 13.0 0.1 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TBCA PF02970.11 EPY52068.1 - 2.3e-20 72.4 1.5 3e-20 72.0 1.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.6 EPY52068.1 - 0.0089 14.7 2.1 0.01 14.5 0.9 1.5 1 1 1 2 2 2 2 Spc7 kinetochore protein NPV_P10 PF05531.7 EPY52068.1 - 0.018 15.2 2.5 0.034 14.3 1.4 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TPR_21 PF09976.4 EPY52068.1 - 0.034 14.0 0.2 3.9 7.3 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Phage_Gp23 PF10669.4 EPY52068.1 - 0.054 13.5 0.3 0.077 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF1664 PF07889.7 EPY52068.1 - 0.12 12.2 2.6 0.15 11.8 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 EPY52068.1 - 0.19 11.4 1.3 0.48 10.1 0.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 EPY52068.1 - 0.3 10.8 3.0 4.3 7.1 0.7 2.7 1 1 1 2 2 2 0 Prefoldin subunit Abhydrolase_2 PF02230.11 EPY52070.1 - 5.1e-68 228.7 0.1 6.1e-68 228.4 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPY52070.1 - 1.4e-10 41.1 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY52070.1 - 8.7e-10 38.8 0.0 2e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY52070.1 - 0.0022 17.6 0.1 0.0073 15.8 0.1 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 EPY52070.1 - 0.0023 17.4 0.0 0.009 15.4 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EPY52070.1 - 0.0055 16.1 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EPY52070.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Rad51 PF08423.6 EPY52071.1 - 1.1e-119 398.0 0.2 2.2e-119 397.1 0.0 1.5 2 0 0 2 2 2 1 Rad51 RecA PF00154.16 EPY52071.1 - 6.5e-13 48.4 0.1 8.7e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EPY52071.1 - 1.1e-08 34.7 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EPY52071.1 - 7e-06 26.1 0.1 2.4e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EPY52071.1 - 0.00058 19.0 0.6 0.0012 18.0 0.4 1.5 1 1 0 1 1 1 1 KaiC DUF128 PF01995.11 EPY52071.1 - 0.065 12.1 0.1 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF128 14-3-3 PF00244.15 EPY52072.1 - 6.8e-114 378.8 9.2 7.7e-114 378.6 6.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EPY52072.1 - 0.013 15.0 1.8 1.7 8.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF3802 PF12290.3 EPY52072.1 - 0.11 12.7 1.6 1 9.7 0.1 2.8 3 1 0 4 4 4 0 Protein of unknown function (DUF3802) Glyco_hydro_32N PF00251.15 EPY52073.1 - 6.9e-92 308.0 0.7 8.3e-92 307.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EPY52073.1 - 3.3e-09 36.9 0.0 9.7e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal SNAP PF14938.1 EPY52074.1 - 3.1e-101 338.2 18.5 3.5e-101 338.0 12.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 EPY52074.1 - 0.008 16.5 16.9 0.61 10.6 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF4498 PF14926.1 EPY52074.1 - 0.049 12.7 0.4 0.081 12.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) TPR_7 PF13176.1 EPY52074.1 - 2 8.4 10.4 21 5.2 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52074.1 - 7.3 7.5 16.1 52 4.8 0.1 5.6 2 1 4 6 6 6 0 Tetratricopeptide repeat BING4CT PF08149.6 EPY52075.1 - 2.5e-39 132.6 0.0 1.9e-37 126.5 0.0 3.0 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 EPY52075.1 - 1.4e-09 37.4 0.0 6.3e-06 25.8 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPY52075.1 - 2.4e-05 23.3 0.0 4.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region DUF3713 PF12506.3 EPY52075.1 - 0.33 11.0 4.1 12 5.9 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) eIF3_subunit PF08597.5 EPY52076.1 - 2.6 7.5 9.6 1.2 8.5 5.1 1.5 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Sen15 PF09631.5 EPY52077.1 - 6.1e-26 90.6 0.1 7.5e-26 90.3 0.1 1.1 1 0 0 1 1 1 1 Sen15 protein FHIPEP PF00771.15 EPY52077.1 - 0.022 13.1 0.1 0.026 12.8 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family Glyco_transf_15 PF01793.11 EPY52078.1 - 1e-43 149.5 2.7 1.2e-43 149.3 1.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Thioredoxin PF00085.15 EPY52079.1 - 2.1e-14 53.0 0.0 1.1e-07 31.4 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 EPY52079.1 - 1.1e-06 28.5 0.1 0.00081 19.2 0.0 3.5 2 1 1 4 4 4 1 Thioredoxin-like domain HyaE PF07449.6 EPY52079.1 - 0.00013 21.7 0.0 0.44 10.4 0.0 3.2 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Abhydrolase_5 PF12695.2 EPY52080.1 - 6.9e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY52080.1 - 0.0018 18.1 0.0 0.013 15.4 0.1 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPY52080.1 - 0.032 13.4 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EPY52080.1 - 0.13 11.7 0.3 0.62 9.5 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPY52080.1 - 0.14 11.5 1.0 1 8.7 0.7 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Ribosomal_S4e PF00900.15 EPY52081.1 - 7.3e-34 115.2 0.5 1.4e-33 114.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPY52081.1 - 9.2e-19 67.0 6.4 1.9e-18 65.9 4.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPY52081.1 - 7e-06 25.3 0.0 1.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPY52081.1 - 0.00074 19.1 0.4 0.00074 19.1 0.3 2.7 3 0 0 3 3 3 1 KOW motif Apc5 PF12862.2 EPY52082.1 - 1.6e-31 108.0 1.7 1.6e-31 108.0 1.2 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 Ribosomal_L21e PF01157.13 EPY52083.1 - 2.1e-40 136.5 5.3 3.3e-40 135.9 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e BCNT PF07572.7 EPY52083.1 - 0.032 14.1 1.1 0.05 13.5 0.8 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development Rad21_Rec8_N PF04825.8 EPY52084.1 - 5.4e-42 142.2 0.0 1e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPY52084.1 - 7e-13 47.5 0.0 1.8e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Parathyroid PF01279.12 EPY52084.1 - 0.049 14.2 2.1 0.14 12.8 1.4 1.7 1 0 0 1 1 1 0 Parathyroid hormone family ScpA_ScpB PF02616.9 EPY52084.1 - 0.061 12.8 0.0 0.061 12.8 0.0 2.4 3 0 0 3 3 3 0 ScpA/B protein F-box PF00646.28 EPY52085.1 - 3.6e-12 45.5 1.0 2.1e-11 43.1 0.3 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EPY52085.1 - 1.5e-11 43.8 0.2 4.6e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 EPY52085.1 - 2.5e-07 30.2 5.6 1.3e-05 24.7 0.1 2.3 1 1 1 2 2 2 2 TPR repeat NARP1 PF12569.3 EPY52085.1 - 0.00043 19.1 0.4 0.00076 18.3 0.0 1.5 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 LRR_4 PF12799.2 EPY52085.1 - 0.013 15.1 17.4 1.4 8.5 0.0 5.6 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) TPR_9 PF13371.1 EPY52085.1 - 0.037 13.8 0.6 0.07 13.0 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPY52085.1 - 0.05 13.2 6.0 1.6 8.4 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52085.1 - 0.12 13.0 0.8 0.77 10.5 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52085.1 - 0.21 11.5 6.3 6.1 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.1 EPY52085.1 - 0.64 10.2 8.2 8 6.8 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich repeat FNIP PF05725.7 EPY52085.1 - 4.4 7.3 8.2 0.95 9.4 0.7 3.2 3 0 0 3 3 3 0 FNIP Repeat LRR_8 PF13855.1 EPY52085.1 - 5.1 6.9 17.8 0.38 10.5 2.4 4.7 3 2 3 6 6 6 0 Leucine rich repeat DDOST_48kD PF03345.9 EPY52086.1 - 2.7e-126 421.5 0.1 3.3e-126 421.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta PfkB PF00294.19 EPY52087.1 - 2.2e-69 233.9 0.4 2.5e-69 233.7 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPY52087.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase cNMP_binding PF00027.24 EPY52087.1 - 0.044 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain COG4 PF08318.7 EPY52088.1 - 3.4e-87 292.3 5.6 6.7e-87 291.3 3.9 1.5 1 0 0 1 1 1 1 COG4 transport protein Retrotrans_gag PF03732.12 EPY52088.1 - 2.8 8.0 8.1 0.36 10.9 0.1 3.5 5 0 0 5 5 5 0 Retrotransposon gag protein Inhibitor_I9 PF05922.11 EPY52089.1 - 1.2e-10 41.8 0.5 2.1e-10 41.0 0.4 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF749 PF05370.6 EPY52089.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF749) Methyltransf_16 PF10294.4 EPY52090.1 - 1.6e-18 66.7 0.0 3.1e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EPY52090.1 - 1.8e-05 24.5 0.0 3.9e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY52090.1 - 3.2e-05 24.4 0.0 5.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPY52090.1 - 0.0052 16.3 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EPY52090.1 - 0.0079 15.7 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY52090.1 - 0.03 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PH_8 PF15409.1 EPY52090.1 - 0.088 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain COX4 PF02936.9 EPY52091.1 - 3.2e-48 163.0 0.1 4.1e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SAE2 PF08573.5 EPY52092.1 - 2e-10 41.2 0.5 7.7e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TMF_TATA_bd PF12325.3 EPY52092.1 - 0.0015 18.2 2.7 0.0023 17.6 1.8 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Lzipper-MIP1 PF14389.1 EPY52092.1 - 0.014 15.4 0.7 0.033 14.3 0.5 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.1 EPY52092.1 - 0.024 13.8 1.0 0.04 13.1 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 EPY52092.1 - 0.11 10.7 0.5 0.19 10.0 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Rho_Binding PF08912.6 EPY52092.1 - 7.7 6.9 7.8 1.3 9.4 2.2 1.9 2 0 0 2 2 2 0 Rho Binding NARP1 PF12569.3 EPY52093.1 - 1.4e-178 594.9 21.7 6.2e-177 589.4 13.0 2.5 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EPY52093.1 - 2.1e-10 40.1 19.4 0.0082 15.7 0.2 6.5 7 1 1 8 8 8 3 TPR repeat TPR_12 PF13424.1 EPY52093.1 - 8.9e-09 35.1 16.4 0.033 14.1 0.1 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52093.1 - 9.5e-09 35.7 9.2 0.59 10.8 0.1 7.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52093.1 - 9.9e-09 35.4 14.8 0.14 12.5 1.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52093.1 - 3.7e-07 29.5 26.6 0.5 10.4 0.3 9.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52093.1 - 2e-06 27.5 4.5 0.51 10.6 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52093.1 - 1.1e-05 25.6 6.6 0.4 11.4 0.1 7.0 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPY52093.1 - 2.6e-05 23.9 1.1 1.1 9.1 0.0 4.6 4 1 0 5 5 5 1 Tetratricopeptide repeat NYD-SP12_N PF15015.1 EPY52093.1 - 0.0051 15.1 0.0 0.012 13.9 0.0 1.5 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_8 PF13181.1 EPY52093.1 - 0.019 14.7 7.6 0.26 11.1 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4316 PF14195.1 EPY52093.1 - 0.035 14.1 0.5 0.11 12.5 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) TPR_4 PF07721.9 EPY52093.1 - 0.14 12.6 2.3 10 6.8 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY52093.1 - 0.18 12.3 18.4 0.7 10.4 0.7 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPY52093.1 - 1.9 8.3 13.2 3.6 7.5 0.0 5.6 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 EPY52093.1 - 7.2 6.4 29.0 6.6 6.5 0.4 7.9 9 1 0 9 9 9 0 Tetratricopeptide repeat HSP20 PF00011.16 EPY52094.1 - 8.8e-20 70.4 0.0 1e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EPY52094.1 - 0.029 13.9 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) CS PF04969.11 EPY52094.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 CS domain UQ_con PF00179.21 EPY52095.1 - 9.1e-18 64.0 0.0 9.8e-18 63.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPY52095.1 - 0.003 17.4 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain Cid2 PF09774.4 EPY52096.1 - 3.1e-35 121.5 1.1 3.5e-35 121.3 0.8 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 adh_short_C2 PF13561.1 EPY52098.1 - 1.8e-33 116.3 0.0 2.1e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPY52098.1 - 6.4e-28 97.7 0.0 7.7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY52098.1 - 1.7e-10 40.8 0.0 2.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPY52098.1 - 0.03 13.4 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EPY52098.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Alpha-amylase PF00128.19 EPY52099.1 - 8.4e-24 84.5 11.2 1.7e-18 67.1 1.4 4.0 2 1 1 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPY52099.1 - 2e-17 63.5 0.1 4.5e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPY52099.1 - 1.4e-07 31.1 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 TUDOR PF00567.19 EPY52100.1 - 0.00016 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Tudor domain DUF4537 PF15057.1 EPY52100.1 - 0.0019 17.9 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.5 EPY52100.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor H-kinase_dim PF02895.9 EPY52100.1 - 0.074 13.4 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF1077 PF06417.7 EPY52101.1 - 1.7e-46 156.6 3.1 2.1e-46 156.3 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF2542 PF10808.3 EPY52101.1 - 0.29 11.4 2.1 2 8.7 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2542) CRC_subunit PF08624.5 EPY52102.1 - 4.7e-57 191.8 0.0 7e-57 191.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit EF-1_beta_acid PF10587.4 EPY52102.1 - 0.17 12.0 4.5 0.43 10.7 3.1 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region FA_desaturase PF00487.19 EPY52103.1 - 1.8e-18 66.9 19.4 1.8e-18 66.9 13.4 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EPY52103.1 - 1.1e-09 37.9 0.0 2.5e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GST_N_2 PF13409.1 EPY52104.1 - 2.8e-21 75.2 0.0 6.3e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPY52104.1 - 8.9e-16 57.5 0.0 5.8e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPY52104.1 - 0.00017 21.7 0.0 0.0025 17.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPY52104.1 - 0.00018 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY52104.1 - 0.00021 21.7 0.0 0.00055 20.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HHV6-IE PF03753.8 EPY52105.1 - 0.014 12.9 0.8 0.016 12.7 0.6 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Histone PF00125.19 EPY52106.1 - 7.8e-26 90.0 0.0 1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY52106.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPY52107.1 - 3.2e-23 81.6 0.3 4.4e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY52107.1 - 1.8e-06 27.8 0.1 3.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EPY52107.1 - 6.7e-05 23.0 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Sec5 PF15469.1 EPY52108.1 - 4.1e-21 75.5 2.0 1e-20 74.2 1.4 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 LMBR1 PF04791.11 EPY52109.1 - 4.9e-80 269.3 34.1 1e-79 268.3 23.7 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein ELFV_dehydrog PF00208.16 EPY52110.1 - 2.5e-77 259.7 2.1 3.1e-77 259.4 1.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EPY52110.1 - 5.2e-46 155.4 0.0 1.1e-45 154.3 0.0 1.6 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EPY52110.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding RIX1 PF08167.7 EPY52111.1 - 0.0048 16.5 5.7 0.41 10.3 0.6 4.7 4 1 0 4 4 4 2 rRNA processing/ribosome biogenesis ArfGap PF01412.13 EPY52112.1 - 9e-37 125.4 1.7 1.7e-36 124.5 0.0 2.2 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf DUF4637 PF15470.1 EPY52113.1 - 3.2 7.3 5.3 5.1 6.6 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF999 PF06198.6 EPY52115.1 - 1.5e-12 47.5 2.4 1.6e-11 44.1 1.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF999) DUF2207 PF09972.4 EPY52115.1 - 0.0011 17.5 0.7 0.0012 17.4 0.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3675 PF12428.3 EPY52115.1 - 0.091 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) JmjC PF02373.17 EPY52116.1 - 1.4e-08 34.9 0.1 5e-07 29.9 0.1 3.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase AP_endonuc_2 PF01261.19 EPY52117.1 - 4.6e-26 91.4 0.1 6.5e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribosomal_L6e PF01159.14 EPY52118.1 - 7.8e-36 122.6 0.0 1e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 EPY52118.1 - 0.062 13.0 0.1 0.23 11.2 0.1 2.0 1 1 1 2 2 2 0 KOW motif MFS_1 PF07690.11 EPY52119.1 - 1.8e-16 59.8 45.2 1.5e-15 56.8 30.8 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Cupin_8 PF13621.1 EPY52120.1 - 6e-54 183.1 0.0 8.6e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EPY52120.1 - 0.00022 20.5 0.1 0.0015 17.8 0.0 2.5 3 0 0 3 3 3 1 Cupin superfamily protein TFIID-18kDa PF02269.11 EPY52121.1 - 8.1e-38 128.1 1.8 1.1e-37 127.7 0.5 1.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit DUF3499 PF12005.3 EPY52121.1 - 0.036 14.2 0.5 0.098 12.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) BLUF PF04940.7 EPY52121.1 - 0.094 12.4 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Sensors of blue-light using FAD Metallopep PF12044.3 EPY52121.1 - 0.1 11.0 3.3 0.66 8.3 0.1 2.1 1 1 1 2 2 2 0 Putative peptidase family Carb_kinase PF01256.12 EPY52122.1 - 3.6e-55 186.8 0.0 4.2e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EPY52122.1 - 0.0013 17.9 0.0 0.0054 15.9 0.0 1.8 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Yip1 PF04893.12 EPY52123.1 - 7.5e-09 35.3 12.4 1.2e-08 34.6 8.6 1.3 1 0 0 1 1 1 1 Yip1 domain DUF788 PF05620.6 EPY52123.1 - 5.4 6.8 6.4 1.4 8.7 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Ima1_N PF09779.4 EPY52124.1 - 4.8e-30 104.7 1.7 9.8e-30 103.7 1.2 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain zf-Sec23_Sec24 PF04810.10 EPY52124.1 - 0.035 13.6 1.9 0.057 12.9 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger PHD PF00628.24 EPY52124.1 - 0.2 11.3 4.7 4.7 6.9 0.0 2.8 3 0 0 3 3 3 0 PHD-finger UCR_14kD PF02271.11 EPY52125.1 - 1.3e-39 134.1 0.7 1.5e-39 133.9 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF3313 PF11769.3 EPY52125.1 - 0.11 11.8 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) DUF3294 PF07957.6 EPY52126.1 - 6.6e-14 51.9 17.4 8.7e-14 51.5 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) MerR_1 PF13411.1 EPY52126.1 - 0.58 9.9 4.9 0.86 9.4 1.6 2.2 2 0 0 2 2 2 0 MerR HTH family regulatory protein Abhydrolase_2 PF02230.11 EPY52126.1 - 0.91 8.9 2.7 1.2 8.5 0.0 2.4 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase DENN PF02141.16 EPY52127.1 - 4.7e-49 166.6 2.0 8.9e-49 165.7 1.4 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EPY52127.1 - 8e-16 57.7 0.3 2.8e-15 56.0 0.2 2.0 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 EPY52127.1 - 2.3e-14 53.1 5.3 5.8e-14 51.9 3.6 1.7 1 0 0 1 1 1 1 dDENN domain SET PF00856.23 EPY52128.1 - 1.9e-11 44.5 1.1 1.8e-07 31.5 0.1 2.3 2 1 1 3 3 3 2 SET domain Pkinase PF00069.20 EPY52130.1 - 2.9e-61 206.8 0.0 4.4e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52130.1 - 1.2e-34 119.5 0.0 1.7e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY52130.1 - 9.4e-08 31.3 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Chorismate_synt PF01264.16 EPY52131.1 - 5.8e-127 422.9 0.1 1.1e-126 421.9 0.1 1.4 1 1 0 1 1 1 1 Chorismate synthase BTD PF09270.5 EPY52132.1 - 2.6e-22 79.2 0.1 3.2e-15 56.2 0.0 2.4 1 1 1 2 2 2 2 Beta-trefoil DNA-binding domain Recep_L_domain PF01030.19 EPY52134.1 - 1.5e-13 50.6 11.0 1.6e-05 24.8 0.6 5.6 1 1 4 5 5 5 3 Receptor L domain Ecm33 PF12454.3 EPY52134.1 - 0.01 15.7 0.1 0.028 14.3 0.0 1.8 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein LRR_5 PF13306.1 EPY52134.1 - 0.01 15.5 0.7 0.01 15.5 0.5 2.3 1 1 0 2 2 2 0 Leucine rich repeats (6 copies) Glyco_transf_21 PF13506.1 EPY52134.1 - 0.02 14.1 0.1 0.091 12.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 PP2C PF00481.16 EPY52135.1 - 8.7e-87 290.7 0.0 1.2e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C EAF PF09816.4 EPY52136.1 - 2.5e-21 75.7 0.0 5.5e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Uricase PF01014.13 EPY52137.1 - 3.6e-67 224.6 2.4 4.3e-35 120.7 0.9 2.0 2 0 0 2 2 2 2 Uricase Aldo_ket_red PF00248.16 EPY52138.1 - 1.7e-09 36.9 0.0 1.8e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FSH1 PF03959.8 EPY52139.1 - 5.4e-64 215.5 0.0 8.6e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DHFR_1 PF00186.14 EPY52139.1 - 6.2e-26 90.9 0.0 8.6e-25 87.1 0.0 2.1 1 1 0 1 1 1 1 Dihydrofolate reductase Abhydrolase_5 PF12695.2 EPY52139.1 - 5.8e-09 35.8 0.0 4.4e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY52139.1 - 0.00054 19.8 0.0 1.9 8.2 0.0 3.4 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPY52139.1 - 0.032 13.6 0.1 0.087 12.2 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase tRNA-synt_2 PF00152.15 EPY52140.1 - 5.8e-80 268.5 0.1 9.4e-80 267.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPY52140.1 - 3.4e-06 26.8 0.3 6.1e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPY52140.1 - 0.021 14.0 0.2 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF4557 PF15101.1 EPY52140.1 - 0.13 12.0 1.5 0.22 11.3 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Kelch_3 PF13415.1 EPY52141.1 - 6e-44 147.2 5.7 2.3e-11 43.4 0.0 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EPY52141.1 - 8.9e-44 147.0 8.9 1.5e-10 40.6 0.0 6.5 4 1 2 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EPY52141.1 - 1.2e-37 127.2 6.5 8.9e-08 31.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EPY52141.1 - 4.3e-34 115.8 0.0 7.2e-09 35.0 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EPY52141.1 - 1.6e-30 104.0 4.1 2.6e-07 30.5 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EPY52141.1 - 2e-29 100.1 3.6 4.6e-06 26.1 0.1 5.8 5 0 0 5 5 5 5 Kelch motif Ribosomal_L37e PF01907.14 EPY52142.1 - 2.2e-25 88.1 14.5 2.2e-25 88.1 10.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 EPY52142.1 - 0.00099 18.8 2.7 0.0015 18.3 1.9 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-C3HC4_2 PF13923.1 EPY52142.1 - 0.12 12.3 3.9 0.2 11.7 2.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY52142.1 - 0.13 12.0 3.5 0.2 11.4 2.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.14 EPY52142.1 - 0.19 11.4 1.1 0.27 10.9 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EPY52142.1 - 0.5 9.6 3.8 1.8 7.8 2.7 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC4 PF00097.20 EPY52142.1 - 0.81 9.4 5.4 1.3 8.7 3.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 EPY52142.1 - 0.86 9.1 6.3 1.6 8.2 4.4 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DNA_RNApol_7kD PF03604.8 EPY52142.1 - 7.4 6.1 7.3 4.7 6.7 1.2 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_4 PF13894.1 EPY52142.1 - 7.5 7.1 7.1 3.9e+02 1.7 4.9 2.7 1 1 0 1 1 1 0 C2H2-type zinc finger DASH_Spc19 PF08287.6 EPY52143.1 - 4.1e-35 120.6 10.0 2.4e-34 118.1 7.0 1.8 1 1 0 1 1 1 1 Spc19 DASH_Dam1 PF08653.5 EPY52143.1 - 0.026 14.2 0.3 8.6 6.2 0.1 2.8 2 1 0 2 2 2 0 DASH complex subunit Dam1 NOP5NT PF08156.8 EPY52143.1 - 0.039 14.1 0.8 0.066 13.3 0.3 1.6 2 0 0 2 2 2 0 NOP5NT (NUC127) domain NPV_P10 PF05531.7 EPY52143.1 - 0.05 13.8 2.9 3.5 7.9 0.4 2.9 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Muted PF14942.1 EPY52143.1 - 0.081 12.7 3.3 0.25 11.2 1.7 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Rogdi_lz PF10259.4 EPY52143.1 - 0.099 11.7 2.5 0.7 8.9 0.1 2.6 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein Prefoldin PF02996.12 EPY52143.1 - 0.15 11.7 6.1 6.4 6.4 0.0 3.2 2 1 0 3 3 3 0 Prefoldin subunit AKNA PF12443.3 EPY52143.1 - 0.19 11.7 7.8 0.61 10.1 1.4 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor Cep57_CLD_2 PF14197.1 EPY52143.1 - 0.28 11.1 9.2 0.23 11.4 3.6 2.5 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Prefoldin_2 PF01920.15 EPY52143.1 - 1.4 8.6 7.5 0.73 9.6 0.7 3.1 3 1 0 3 3 3 0 Prefoldin subunit DivIC PF04977.10 EPY52143.1 - 2.7 7.5 8.7 1.6 8.2 1.0 3.1 2 1 2 4 4 4 0 Septum formation initiator TMF_DNA_bd PF12329.3 EPY52143.1 - 7.2 6.5 6.9 18 5.2 2.1 3.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding SET PF00856.23 EPY52144.1 - 5.4e-10 39.8 0.0 8.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 SET domain NMT1 PF09084.6 EPY52145.1 - 2e-73 246.5 0.0 2.5e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 EPY52145.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.1 EPY52145.1 - 0.0093 15.3 0.0 0.063 12.6 0.0 2.3 1 1 0 1 1 1 1 NMT1-like family DUP PF00674.13 EPY52146.1 - 0.056 13.4 0.3 32 4.5 0.0 3.3 2 1 1 3 3 3 0 DUP family RNA_pol_Rpc82 PF05645.8 EPY52147.1 - 2.9e-51 174.5 2.4 4.8e-51 173.7 1.7 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EPY52147.1 - 6e-21 74.0 0.4 4.9e-19 67.9 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EPY52147.1 - 3.5e-11 42.5 1.2 0.00027 20.4 0.0 3.0 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 EPY52147.1 - 0.00013 21.5 0.2 0.035 13.8 0.0 3.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 EPY52147.1 - 0.053 13.1 0.6 0.39 10.3 0.0 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain CPSase_L_D3 PF02787.14 EPY52147.1 - 0.17 11.6 2.5 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain WD40 PF00400.27 EPY52148.1 - 2.2e-16 59.0 10.9 5.7e-05 22.8 0.0 7.1 8 0 0 8 8 8 3 WD domain, G-beta repeat DUF3639 PF12341.3 EPY52148.1 - 3.7e-09 36.4 1.1 1.3e-08 34.6 0.8 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EPY52148.1 - 0.00029 20.6 0.3 0.065 12.9 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 EPY52148.1 - 0.043 12.8 0.0 0.27 10.1 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BC10 PF06726.7 EPY52149.1 - 3.3e-14 52.6 7.3 4.7e-14 52.1 5.0 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF3245 PF11595.3 EPY52150.1 - 1.5e-17 64.2 10.2 1.7e-17 64.0 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) G-patch_2 PF12656.2 EPY52150.1 - 0.039 13.7 0.0 0.039 13.7 0.0 2.4 2 1 0 2 2 2 0 DExH-box splicing factor binding site DUF4414 PF14377.1 EPY52150.1 - 0.09 12.6 3.8 0.17 11.8 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) PBP1_TM PF14812.1 EPY52150.1 - 0.74 10.1 7.8 1.4 9.2 5.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DHHW PF14286.1 EPY52150.1 - 2.7 7.2 6.2 3.4 6.8 4.3 1.4 1 1 0 1 1 1 0 DHHW protein Vfa1 PF08432.5 EPY52150.1 - 5.2 7.0 11.8 7.4 6.5 8.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF605 PF04652.11 EPY52151.1 - 0.025 13.9 6.6 0.034 13.5 4.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1064 PF06356.6 EPY52151.1 - 0.032 14.2 0.3 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1064) Sulfotransfer_1 PF00685.22 EPY52151.1 - 0.049 12.8 1.0 0.17 11.1 0.7 1.8 1 1 0 1 1 1 0 Sulfotransferase domain PUF PF00806.14 EPY52153.1 - 1e-57 188.4 13.6 8e-08 31.3 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat YqzH PF14164.1 EPY52153.1 - 0.00033 20.5 0.2 0.0042 16.9 0.0 2.4 2 0 0 2 2 2 1 YqzH-like protein BRCT PF00533.21 EPY52154.1 - 1.1e-09 38.3 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EPY52154.1 - 2.1e-06 27.4 0.4 9.6e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) PTCB-BRCT PF12738.2 EPY52154.1 - 4.4e-06 26.4 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 EPY52154.1 - 0.00019 21.5 0.0 0.00068 19.7 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain Cu-oxidase_3 PF07732.10 EPY52154.1 - 0.027 14.1 0.1 0.074 12.7 0.1 1.7 1 0 0 1 1 1 0 Multicopper oxidase Synaptobrevin PF00957.16 EPY52156.1 - 9.1e-34 114.9 0.9 1.1e-33 114.7 0.6 1.1 1 0 0 1 1 1 1 Synaptobrevin AAA_11 PF13086.1 EPY52157.1 - 7.9e-72 241.6 0.5 1.9e-71 240.3 0.3 1.7 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 EPY52157.1 - 3.1e-66 223.9 31.7 1.3e-47 162.3 9.0 2.2 2 0 0 2 2 2 2 SEN1 N terminal AAA_12 PF13087.1 EPY52157.1 - 1.4e-64 217.1 1.0 1.4e-64 217.1 0.7 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPY52157.1 - 1.7e-11 43.6 0.0 1.1e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EPY52157.1 - 6.3e-08 32.4 1.4 0.016 14.7 0.1 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EPY52157.1 - 2.7e-06 27.1 0.0 0.0054 16.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain DEAD PF00270.24 EPY52157.1 - 0.00017 21.1 0.7 0.55 9.7 0.0 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 EPY52157.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.10 EPY52157.1 - 0.0088 15.8 0.9 0.1 12.4 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPY52157.1 - 0.072 13.2 0.6 3.2 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EPY52157.1 - 0.14 11.4 0.0 0.35 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain UCH PF00443.24 EPY52158.1 - 5.8e-53 179.7 0.0 7.4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY52158.1 - 2.4e-21 76.4 0.9 5.7e-21 75.2 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EPY52158.1 - 5.6e-13 48.0 0.0 1.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L24e PF01246.15 EPY52159.1 - 8.1e-31 105.7 0.2 8.1e-31 105.7 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e ATP-synt_E PF05680.7 EPY52159.1 - 9 6.3 12.7 1.9 8.5 4.4 2.2 1 1 1 2 2 2 0 ATP synthase E chain ARPC4 PF05856.7 EPY52160.1 - 4.3e-73 244.2 3.9 4.7e-73 244.1 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) PACT_coil_coil PF10495.4 EPY52161.1 - 9.9e-22 76.6 0.7 4.9e-21 74.4 0.5 2.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Microtub_assoc PF07989.6 EPY52161.1 - 3.2e-19 68.5 3.6 3.2e-19 68.5 2.5 9.0 6 3 3 9 9 9 1 Microtubule associated LPP PF04728.8 EPY52161.1 - 0.54 10.0 12.7 1.2 8.9 0.2 5.9 6 0 0 6 6 6 0 Lipoprotein leucine-zipper NUDIX PF00293.23 EPY52162.1 - 1.6e-14 53.7 0.0 2.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain EFP PF01132.15 EPY52162.1 - 0.0082 15.7 0.2 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Sec7 PF01369.15 EPY52163.1 - 8.5e-08 32.0 0.7 8.5e-08 32.0 0.5 2.5 3 0 0 3 3 3 1 Sec7 domain PH_9 PF15410.1 EPY52163.1 - 7.3e-07 29.3 0.0 2.5e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPY52163.1 - 0.00011 22.3 1.2 0.00026 21.1 0.1 2.3 2 0 0 2 2 2 1 PH domain Rtt106 PF08512.7 EPY52164.1 - 2e-22 78.9 0.2 3.6e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PUF PF00806.14 EPY52165.1 - 6.7e-15 53.6 0.0 0.16 11.4 0.0 7.8 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat DUF1764 PF08576.5 EPY52166.1 - 2.8e-21 76.1 5.9 3.4e-21 75.9 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) zf-H2C2_2 PF13465.1 EPY52167.1 - 1.8e-08 34.2 7.6 0.00093 19.3 0.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPY52167.1 - 0.00011 22.3 23.4 0.0038 17.4 1.9 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY52167.1 - 0.00057 20.0 16.7 0.034 14.4 1.3 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPY52167.1 - 0.033 14.1 2.3 0.44 10.5 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPY52167.1 - 0.13 12.4 3.8 0.35 11.0 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPY52167.1 - 1.7 8.9 9.0 0.19 12.0 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ubiquitin PF00240.18 EPY52168.1 - 1.9e-33 113.6 1.6 2.4e-33 113.3 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EPY52168.1 - 8.5e-25 86.3 2.3 1.8e-24 85.3 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EPY52168.1 - 6.7e-19 67.3 0.4 1.3e-18 66.4 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPY52168.1 - 2.1e-05 24.6 0.3 0.00019 21.6 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPY52168.1 - 0.0009 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPY52168.1 - 0.0025 17.6 0.2 0.0042 16.9 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2318 PF10080.4 EPY52168.1 - 0.018 14.7 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DZR PF12773.2 EPY52168.1 - 0.023 14.4 0.3 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF2407 PF10302.4 EPY52168.1 - 0.038 14.1 0.3 0.051 13.7 0.2 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPY52168.1 - 0.081 12.9 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) OrfB_Zn_ribbon PF07282.6 EPY52168.1 - 0.2 11.3 1.1 0.46 10.1 0.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Plexin_cytopl PF08337.7 EPY52168.1 - 0.21 9.8 1.6 1.2 7.3 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-ribbon_3 PF13248.1 EPY52168.1 - 0.39 10.0 2.5 0.85 8.9 1.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain MMtag PF10159.4 EPY52169.1 - 6.8e-26 90.1 5.8 1.3e-25 89.2 4.0 1.5 1 0 0 1 1 1 1 Kinase phosphorylation protein MliC PF09864.4 EPY52169.1 - 0.26 11.0 1.3 0.55 10.0 0.9 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Glyco_hydro_63 PF03200.11 EPY52170.1 - 1.6e-248 826.7 7.3 1.1e-247 823.9 5.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EPY52170.1 - 7.6e-07 28.1 0.1 1.3e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EPY52170.1 - 0.0054 15.5 0.0 0.0099 14.6 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Iso_dh PF00180.15 EPY52171.1 - 3.1e-70 236.8 0.0 4.4e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MiAMP1 PF09117.5 EPY52171.1 - 0.059 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 MiAMP1 MIF4G_like PF09088.6 EPY52172.1 - 7.9e-76 253.7 2.0 1.7e-75 252.7 1.4 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EPY52172.1 - 1.4e-35 122.7 6.8 2.6e-35 121.8 4.7 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EPY52172.1 - 1.9e-05 24.1 0.5 1.9e-05 24.1 0.4 2.1 3 0 0 3 3 3 1 MIF4G domain DAO PF01266.19 EPY52173.1 - 2.8e-28 98.8 0.0 5.4e-18 65.0 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase DUF1958 PF09211.5 EPY52173.1 - 0.009 16.0 0.1 0.053 13.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1958) TRAPPC9-Trs120 PF08626.6 EPY52174.1 - 6e-251 835.3 10.5 7.1e-251 835.1 7.3 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_1 PF00515.23 EPY52174.1 - 0.039 13.5 1.4 0.14 11.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPY52174.1 - 0.11 12.1 0.2 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EPY52174.1 - 0.12 12.3 0.6 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Proteasome PF00227.21 EPY52175.1 - 6.2e-50 169.1 0.0 7.5e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPY52175.1 - 5.8e-13 47.8 0.0 1.5e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Abhydrolase_6 PF12697.2 EPY52176.1 - 1.8e-27 96.7 0.0 2.5e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY52176.1 - 1.9e-20 73.4 0.1 3.6e-19 69.2 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPY52176.1 - 1.3e-12 47.6 0.0 1.8e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPY52176.1 - 3.6e-05 23.4 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EPY52176.1 - 0.00013 21.5 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 EPY52176.1 - 0.00052 19.6 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.9 EPY52176.1 - 0.002 16.6 0.0 0.005 15.3 0.0 1.6 2 0 0 2 2 2 1 Ndr family Lipase_3 PF01764.20 EPY52176.1 - 0.0057 16.2 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EPY52176.1 - 0.01 14.9 0.1 0.083 11.9 0.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 EPY52176.1 - 0.016 14.4 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.8 EPY52176.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 EPY52176.1 - 0.029 14.0 0.2 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF2305 PF10230.4 EPY52176.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) FSH1 PF03959.8 EPY52176.1 - 0.13 11.6 0.3 11 5.3 0.0 2.7 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Kelch_3 PF13415.1 EPY52177.1 - 7.7e-24 83.2 0.0 1.3e-08 34.7 0.0 4.0 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EPY52177.1 - 2.4e-20 72.0 0.3 5e-06 26.3 0.0 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EPY52177.1 - 4.1e-18 64.6 5.4 7.1e-06 25.9 0.1 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EPY52177.1 - 2.4e-17 62.4 5.1 6.5e-08 32.2 0.1 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EPY52177.1 - 7.1e-17 60.6 0.7 6.8e-07 28.7 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 EPY52177.1 - 4.8e-16 57.8 5.1 2.2e-07 30.3 0.2 4.8 5 0 0 5 5 5 3 Kelch motif bZIP_1 PF00170.16 EPY52177.1 - 0.58 10.1 23.5 0.56 10.1 0.2 5.2 3 1 2 5 5 5 0 bZIP transcription factor Fungal_trans PF04082.13 EPY52178.1 - 1.1e-26 93.3 3.3 1.1e-26 93.3 2.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY52178.1 - 1.4e-08 34.4 11.9 3.1e-08 33.4 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOB1_Zn_bind PF08772.6 EPY52179.1 - 1.7e-29 101.4 3.4 3.5e-29 100.4 2.3 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 EPY52179.1 - 0.056 13.2 0.4 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon AF1Q PF15017.1 EPY52179.1 - 0.3 11.0 18.1 3.7 7.5 12.6 2.3 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator RWD PF05773.17 EPY52180.1 - 8.8e-18 64.2 0.0 2.2e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EPY52180.1 - 2e-16 59.5 17.8 1.5e-11 44.0 3.4 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EPY52180.1 - 0.00019 21.3 12.4 0.00019 21.3 8.6 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY52180.1 - 0.00056 19.6 12.6 0.00056 19.6 8.7 4.2 3 2 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EPY52180.1 - 0.0008 19.0 14.1 0.0008 19.0 9.7 4.4 3 2 1 4 4 4 1 zinc-RING finger domain Med6 PF04934.9 EPY52181.1 - 8.8e-48 161.4 0.5 1.4e-47 160.8 0.4 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component MFS_1 PF07690.11 EPY52182.1 - 1e-36 126.3 23.1 1.7e-36 125.7 16.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1281 PF06924.6 EPY52182.1 - 0.01 15.2 0.1 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) UPRTase PF14681.1 EPY52183.1 - 2.3e-45 154.3 0.0 3.3e-38 130.9 0.0 2.1 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPY52183.1 - 3.9e-07 29.8 0.0 1.7e-06 27.7 0.0 1.8 1 1 1 2 2 2 1 Phosphoribosyl transferase domain DUF1688 PF07958.6 EPY52184.1 - 4.2e-142 473.5 0.0 4.9e-142 473.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GTP_CH_N PF12471.3 EPY52185.1 - 8.1e-88 293.1 0.0 1.4e-87 292.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EPY52185.1 - 5.7e-17 61.4 0.0 8.8e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Zn_clus PF00172.13 EPY52186.1 - 1.5e-07 31.2 7.6 3.8e-07 29.8 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPY52186.1 - 5.1 7.3 9.9 12 6.1 1.8 2.8 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region UPRTase PF14681.1 EPY52187.1 - 7.9e-66 221.1 0.0 9e-66 221.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Transp_cyt_pur PF02133.10 EPY52188.1 - 6.8e-165 548.8 44.3 7.7e-165 548.7 30.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PTPLA PF04387.9 EPY52189.1 - 4.7e-50 169.2 13.5 7.4e-50 168.5 9.3 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA LSM PF01423.17 EPY52190.1 - 6.9e-16 57.5 0.2 8.4e-16 57.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPY52190.1 - 0.047 13.6 0.1 0.083 12.8 0.1 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain Kringle PF00051.13 EPY52190.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Kringle domain DUF2392 PF10288.4 EPY52191.1 - 3.2e-21 75.6 0.0 9.1e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EPY52191.1 - 6.8e-06 25.6 0.0 0.037 13.5 0.0 2.7 3 0 0 3 3 3 2 PP-loop family PADR1 PF08063.7 EPY52191.1 - 0.098 12.0 1.3 0.41 10.0 0.9 2.1 1 0 0 1 1 1 0 PADR1 (NUC008) domain DZR PF12773.2 EPY52191.1 - 0.6 9.9 7.3 9.7 6.1 0.6 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 EPY52191.1 - 6.5 6.9 7.6 1.6 8.9 0.9 2.9 3 0 0 3 3 3 0 CHY zinc finger L51_S25_CI-B8 PF05047.11 EPY52192.1 - 3.3e-10 39.5 0.0 5.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2404 PF10296.4 EPY52193.1 - 0.00026 21.0 0.0 0.00064 19.8 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) BAR PF03114.13 EPY52194.1 - 2.7e-40 138.3 5.8 3.8e-40 137.8 4.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EPY52194.1 - 1.6e-12 46.8 0.1 3.5e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPY52194.1 - 2.6e-12 45.9 0.1 5.5e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPY52194.1 - 4.1e-08 32.5 0.0 8.2e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4200 PF13863.1 EPY52194.1 - 0.48 10.3 16.0 1.3 9.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2014 PF09427.5 EPY52195.1 - 2.8e-66 223.3 1.7 4e-66 222.8 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EPY52195.1 - 7.3e-19 67.2 0.5 2.1e-18 65.7 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 EPY52195.1 - 0.0031 17.4 0.2 0.0088 15.9 0.1 1.8 1 0 0 1 1 1 1 bZIP transcription factor CENP-Q PF13094.1 EPY52195.1 - 0.008 16.2 0.3 0.024 14.6 0.2 1.8 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PRP38 PF03371.10 EPY52196.1 - 2.5e-61 206.2 0.0 3.1e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 PRP38 family F_bP_aldolase PF01116.15 EPY52197.1 - 1.1e-92 310.2 0.0 1.2e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pkinase PF00069.20 EPY52198.1 - 2.2e-59 200.7 0.0 3.1e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52198.1 - 2.8e-26 92.1 0.0 1.3e-25 89.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY52198.1 - 7.1e-07 28.4 0.0 2.2e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EPY52198.1 - 6.2e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPY52198.1 - 0.00036 19.6 0.0 0.00059 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cnl2_NKP2 PF09447.5 EPY52198.1 - 0.0055 16.3 2.3 2.3 7.9 0.3 2.4 2 0 0 2 2 2 2 Cnl2/NKP2 family protein Choline_kinase PF01633.15 EPY52198.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EPY52198.1 - 0.029 13.1 0.2 0.075 11.8 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UCH PF00443.24 EPY52199.1 - 1.3e-36 126.1 0.7 2e-36 125.5 0.5 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY52199.1 - 4.9e-15 55.7 10.5 7e-14 51.9 7.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 EPY52200.1 - 1.6e-16 59.4 5.1 2e-16 59.1 3.5 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit TFIIS_C PF01096.13 EPY52200.1 - 0.0021 17.6 1.6 1.3 8.7 0.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) DZR PF12773.2 EPY52200.1 - 0.0032 17.2 0.4 0.0042 16.8 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon NinF PF05810.7 EPY52200.1 - 0.0049 16.6 0.7 0.0063 16.2 0.5 1.1 1 0 0 1 1 1 1 NinF protein OrfB_Zn_ribbon PF07282.6 EPY52200.1 - 0.0049 16.4 1.2 0.0067 16.0 0.8 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HypA PF01155.14 EPY52200.1 - 0.005 16.5 0.2 0.0055 16.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-C3HC PF07967.8 EPY52200.1 - 0.011 15.5 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like DUF2318 PF10080.4 EPY52200.1 - 0.02 14.6 0.3 0.023 14.4 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Ribosomal_S27e PF01667.12 EPY52200.1 - 0.023 14.2 0.8 0.03 13.8 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S27 Nudix_N_2 PF14803.1 EPY52200.1 - 0.042 13.5 0.8 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal UPF0547 PF10571.4 EPY52200.1 - 0.047 13.3 0.8 0.41 10.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Baculo_ME53 PF06061.6 EPY52200.1 - 0.056 12.4 0.2 0.061 12.2 0.2 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 DUF2296 PF10058.4 EPY52200.1 - 0.058 13.1 0.5 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 EPY52200.1 - 0.07 13.0 2.1 0.19 11.6 1.5 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Elf1 PF05129.8 EPY52200.1 - 0.072 12.7 0.8 0.22 11.2 0.6 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 EPY52200.1 - 0.089 12.3 0.9 0.31 10.5 0.6 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EPY52200.1 - 0.093 12.5 1.9 0.26 11.0 1.3 1.7 1 1 0 1 1 1 0 Zinc-ribbon Zn_Tnp_IS1595 PF12760.2 EPY52200.1 - 0.12 12.2 3.1 0.31 10.8 0.3 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 EPY52200.1 - 0.13 11.5 1.8 1.5 8.0 1.4 2.2 1 1 0 1 1 1 0 zinc-ribbon domain DUF1451 PF07295.6 EPY52200.1 - 0.14 11.9 0.9 0.17 11.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) PhnA_Zn_Ribbon PF08274.7 EPY52200.1 - 0.14 11.9 0.2 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-trcl PF13451.1 EPY52200.1 - 0.15 11.7 3.1 5.4 6.7 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain zf-dskA_traR PF01258.12 EPY52200.1 - 0.16 11.7 1.5 4.6 7.0 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn_ribbon_recom PF13408.1 EPY52200.1 - 0.17 12.1 6.8 1.2 9.4 1.4 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Cas_CXXC_CXXC PF09706.5 EPY52200.1 - 0.19 11.9 3.0 7.4 6.8 0.3 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Ribosomal_L44 PF00935.14 EPY52200.1 - 0.26 11.3 3.9 0.6 10.1 0.9 2.0 1 1 1 2 2 2 0 Ribosomal protein L44 Ribosomal_L40e PF01020.12 EPY52200.1 - 0.4 10.3 3.1 0.55 9.8 2.1 1.1 1 0 0 1 1 1 0 Ribosomal L40e family DUF2197 PF09963.4 EPY52200.1 - 0.58 10.1 4.1 9.9 6.2 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-NADH-PPase PF09297.6 EPY52200.1 - 0.74 9.3 4.0 3.3 7.2 2.8 1.9 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_5 PF13719.1 EPY52200.1 - 0.85 9.2 3.6 6.4 6.4 2.5 2.1 1 1 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.3 EPY52200.1 - 0.92 9.5 6.3 1.5 8.8 0.1 2.8 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Mu-like_Com PF10122.4 EPY52200.1 - 0.95 8.5 5.0 8.5 5.5 1.2 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-ISL3 PF14690.1 EPY52200.1 - 1.9 8.6 5.1 1 9.4 0.7 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ribosomal_L37e PF01907.14 EPY52200.1 - 4.7 7.0 5.8 14 5.5 2.9 2.1 1 1 1 2 2 2 0 Ribosomal protein L37e DNA_methylase PF00145.12 EPY52201.1 - 1.9e-38 132.4 0.0 3.4e-38 131.6 0.0 1.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase OB_NTP_bind PF07717.11 EPY52202.1 - 1.3e-29 102.2 0.1 4e-29 100.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPY52202.1 - 8.2e-25 86.7 0.4 5e-24 84.2 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPY52202.1 - 8.6e-15 54.3 0.0 3.3e-14 52.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY52202.1 - 2.4e-08 33.6 0.1 1.4e-07 31.1 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPY52202.1 - 1.6e-05 25.0 2.9 0.00072 19.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EPY52202.1 - 0.0012 17.8 0.0 0.0027 16.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EPY52202.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 EPY52202.1 - 0.0026 17.2 0.0 0.0074 15.7 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain LsmAD PF06741.8 EPY52204.1 - 6.3e-29 99.8 3.1 6.3e-29 99.8 2.2 2.6 2 0 0 2 2 2 1 LsmAD domain DUF202 PF02656.10 EPY52206.1 - 3.8e-13 49.4 3.1 3.8e-13 49.4 2.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EPY52206.1 - 0.056 12.0 0.0 0.069 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DDE_1 PF03184.14 EPY52207.1 - 3.9e-54 183.0 1.0 8.1e-54 182.0 0.2 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPY52207.1 - 1.1e-15 57.1 0.6 1.3e-14 53.7 0.1 3.0 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain WD40 PF00400.27 EPY52208.1 - 1.3e-47 158.0 11.4 1.1e-13 50.5 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 EPY52208.1 - 5.6e-05 22.9 0.8 0.044 13.4 0.0 3.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPY52208.1 - 0.00085 17.5 6.8 1.1 7.3 0.0 4.3 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY52208.1 - 0.0017 17.2 0.3 1.8 7.1 0.0 3.5 1 1 3 4 4 4 2 Nup133 N terminal like Hira PF07569.6 EPY52208.1 - 0.0035 16.5 0.2 0.27 10.4 0.0 3.1 1 1 2 3 3 3 1 TUP1-like enhancer of split Vezatin PF12632.2 EPY52209.1 - 1.6e-15 56.9 9.5 2.3e-15 56.3 6.1 1.6 1 1 1 2 2 2 1 Mysoin-binding motif of peroxisomes DUF421 PF04239.7 EPY52209.1 - 0.0027 17.1 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF421) DUF1361 PF07099.6 EPY52209.1 - 0.024 14.4 4.5 0.053 13.3 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) Glyco_hydro_16 PF00722.16 EPY52210.1 - 1.6e-10 40.5 0.4 1.2e-09 37.7 0.2 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Acatn PF13000.2 EPY52212.1 - 2.5e-178 594.0 37.5 4.2e-93 312.7 10.4 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF2638 PF10937.3 EPY52213.1 - 1.3e-07 32.6 1.8 1.5e-06 29.1 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2638) Ribosomal_S4e PF00900.15 EPY52214.1 - 7.4e-34 115.2 0.5 1.4e-33 114.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPY52214.1 - 9.2e-19 67.0 6.4 1.9e-18 65.9 4.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPY52214.1 - 6.9e-06 25.3 0.0 1.7e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPY52214.1 - 0.00074 19.1 0.4 0.00074 19.1 0.3 2.7 3 0 0 3 3 3 1 KOW motif MerR PF00376.18 EPY52215.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein AMIN PF11741.3 EPY52215.1 - 0.072 13.0 1.1 0.094 12.6 0.7 1.2 1 0 0 1 1 1 0 AMIN domain DPM2 PF07297.7 EPY52216.1 - 5.5e-24 84.2 4.0 6.3e-24 84.0 2.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EPY52216.1 - 0.00013 21.5 4.6 0.00015 21.3 3.2 1.1 1 0 0 1 1 1 1 PIG-P DUF3377 PF11857.3 EPY52216.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4083 PF13314.1 EPY52216.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF2189 PF09955.4 EPY52216.1 - 0.92 9.4 4.4 1.1 9.2 3.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) Homeobox PF00046.24 EPY52219.1 - 6.2e-14 51.3 5.3 6.2e-14 51.3 3.7 2.3 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 EPY52219.1 - 0.0063 15.5 0.8 0.78 8.8 0.1 2.6 2 0 0 2 2 2 2 Homeodomain leucine-zipper encoding, Homez Epimerase PF01370.16 EPY52221.1 - 2e-10 40.5 0.0 6.5e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPY52221.1 - 9.5e-09 35.5 0.1 1.3e-08 35.0 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPY52221.1 - 2.1e-08 33.6 0.0 3.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EPY52221.1 - 1.4e-05 23.9 0.0 0.00035 19.3 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EPY52221.1 - 0.00046 20.1 0.0 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EPY52221.1 - 0.0029 16.5 0.0 0.0042 16.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ApbA PF02558.11 EPY52221.1 - 0.0035 16.7 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EPY52221.1 - 0.061 12.3 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EPY52221.1 - 0.11 12.1 0.2 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EPY52221.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_Mycoplasma PF07672.8 EPY52223.1 - 0.096 11.8 8.4 0.13 11.4 5.8 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF1129 PF06570.6 EPY52223.1 - 0.19 11.0 1.6 0.29 10.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2207 PF09972.4 EPY52223.1 - 1 7.8 3.8 1.4 7.4 2.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2101 PF09874.4 EPY52223.1 - 2.8 7.3 6.6 4.4 6.7 4.2 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2101) FA_desaturase PF00487.19 EPY52223.1 - 4 6.7 8.1 1.1 8.5 3.4 1.8 2 0 0 2 2 2 0 Fatty acid desaturase MRAP PF15183.1 EPY52223.1 - 6.4 6.4 6.4 14 5.3 4.4 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Ribonuc_L-PSP PF01042.16 EPY52224.1 - 0.042 13.6 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Endoribonuclease L-PSP HSP20 PF00011.16 EPY52225.1 - 1.2e-21 76.4 0.3 1.5e-21 76.1 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY52225.1 - 0.029 14.8 0.3 0.1 13.1 0.1 1.9 1 1 0 1 1 1 0 CS domain DUF4097 PF13349.1 EPY52225.1 - 0.068 12.7 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PIH1 PF08190.7 EPY52225.1 - 0.069 12.5 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 BON PF04972.12 EPY52225.1 - 0.095 12.4 0.2 0.5 10.1 0.1 2.0 2 0 0 2 2 2 0 BON domain adh_short PF00106.20 EPY52226.1 - 1.5e-23 83.5 0.0 2.7e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY52226.1 - 6e-10 39.3 0.0 7.9e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPY52226.1 - 5e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EPY52226.1 - 8e-06 25.6 0.1 1.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPY52226.1 - 9.6e-06 25.1 0.4 1.7e-05 24.4 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPY52226.1 - 1.1e-05 24.5 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EPY52226.1 - 0.065 12.4 0.4 0.13 11.5 0.3 1.5 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EPY52226.1 - 0.13 12.0 0.5 0.3 10.8 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 EPY52227.1 - 2.5e-40 137.9 0.0 5.5e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EPY52227.1 - 1.6e-34 118.9 0.0 4.3e-34 117.6 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EPY52227.1 - 7.3e-09 35.3 0.0 1.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPY52227.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPY52227.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPY52227.1 - 0.0077 15.1 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPY52227.1 - 0.021 13.5 0.0 0.078 11.6 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EPY52227.1 - 0.11 12.8 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site RVT_1 PF00078.22 EPY52228.1 - 6.8e-27 94.2 0.1 1.6e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EPY52228.1 - 7.1e-23 80.9 0.3 3.4e-22 78.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.15 EPY52228.1 - 5e-06 26.3 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-H2C2 PF09337.5 EPY52228.1 - 0.036 13.4 0.4 0.22 10.9 0.6 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Apolipoprotein PF01442.13 EPY52228.1 - 0.11 11.9 0.4 0.29 10.5 0.3 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Asp_protease_2 PF13650.1 EPY52228.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease But2 PF09792.4 EPY52229.1 - 9.6e-07 28.6 0.1 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3446 PF11928.3 EPY52229.1 - 0.12 12.6 4.4 0.36 11.0 3.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) MFS_1 PF07690.11 EPY52231.1 - 2.7e-27 95.4 58.6 1.1e-26 93.3 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY52231.1 - 1.3e-08 33.8 35.5 4e-08 32.2 24.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter HSP20 PF00011.16 EPY52232.1 - 1.2e-21 76.4 0.3 1.5e-21 76.1 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY52232.1 - 0.029 14.8 0.3 0.1 13.1 0.1 1.9 1 1 0 1 1 1 0 CS domain DUF4097 PF13349.1 EPY52232.1 - 0.071 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PIH1 PF08190.7 EPY52232.1 - 0.074 12.4 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 BON PF04972.12 EPY52232.1 - 0.097 12.4 0.2 0.5 10.1 0.1 2.0 2 0 0 2 2 2 0 BON domain DUF2424 PF10340.4 EPY52234.1 - 2.2e-68 230.6 0.9 2.5e-68 230.4 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EPY52234.1 - 2.8e-19 69.5 0.0 5.1e-19 68.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3929 PF13066.1 EPY52234.1 - 0.044 13.5 0.2 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) PGAP1 PF07819.8 EPY52234.1 - 0.055 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 EPY52234.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EPY52234.1 - 0.072 11.7 0.0 0.35 9.5 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_1 PF00561.15 EPY52234.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPY52234.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Paramyxo_PCT PF14320.1 EPY52235.1 - 0.089 11.6 0.0 0.095 11.5 0.0 1.0 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered Alpha-amylase PF00128.19 EPY52236.1 - 1.6e-97 326.7 0.5 2.4e-97 326.1 0.4 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EPY52236.1 - 0.04 14.0 0.5 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain IU_nuc_hydro PF01156.14 EPY52237.1 - 7.5e-95 317.7 0.2 8.3e-95 317.5 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3347 PF11827.3 EPY52238.1 - 0.063 13.2 0.2 0.072 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) PID_2 PF14719.1 EPY52238.1 - 0.1 12.2 0.2 0.14 11.7 0.1 1.4 1 1 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Transp_cyt_pur PF02133.10 EPY52239.1 - 9.5e-94 314.4 28.0 1.1e-93 314.1 19.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COMP PF11598.3 EPY52240.1 - 5.9 7.0 7.1 15 5.7 4.9 1.8 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein SR-25 PF10500.4 EPY52241.1 - 1 8.8 11.6 1.4 8.3 8.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HSP20 PF00011.16 EPY52242.1 - 2.2e-21 75.5 0.3 2.8e-21 75.3 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY52242.1 - 0.01 16.3 0.4 0.058 13.9 0.0 2.0 2 0 0 2 2 2 0 CS domain DUF4097 PF13349.1 EPY52242.1 - 0.045 13.3 0.1 0.073 12.6 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) PIH1 PF08190.7 EPY52242.1 - 0.073 12.5 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 MUG2_C PF08593.5 EPY52243.1 - 5.9e-07 29.6 0.2 1.6e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal Filament PF00038.16 EPY52243.1 - 0.025 14.0 2.7 0.029 13.8 0.7 1.7 1 1 0 1 1 1 0 Intermediate filament protein FliE PF02049.13 EPY52243.1 - 0.046 13.7 2.1 0.079 13.0 0.3 2.3 2 1 0 2 2 2 0 Flagellar hook-basal body complex protein FliE Gp-FAR-1 PF05823.7 EPY52243.1 - 0.088 12.7 0.2 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Mod_r PF07200.8 EPY52243.1 - 0.23 11.3 2.7 9.2 6.1 0.1 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein GAT PF03127.9 EPY52243.1 - 0.5 10.3 0.0 0.5 10.3 0.0 2.3 2 1 0 2 2 2 0 GAT domain Syntaxin PF00804.20 EPY52243.1 - 1.8 8.7 5.9 1.1 9.5 1.9 2.3 2 1 1 3 3 3 0 Syntaxin DUF1495 PF07381.6 EPY52245.1 - 0.00038 20.0 1.1 0.84 9.3 0.1 2.3 2 0 0 2 2 2 2 Winged helix DNA-binding domain (DUF1495) Mg-por_mtran_C PF07109.6 EPY52245.1 - 0.00063 19.7 0.0 0.2 11.7 0.0 2.2 1 1 1 2 2 2 2 Magnesium-protoporphyrin IX methyltransferase C-terminus DUF717 PF05338.7 EPY52245.1 - 0.003 17.4 0.4 4.8 7.2 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF717) HhH-GPD PF00730.20 EPY52245.1 - 0.0091 16.2 0.0 2.3 8.5 0.0 2.1 1 1 1 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein SpoVIF PF14069.1 EPY52245.1 - 0.013 15.1 0.2 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F TFIIE_alpha PF02002.12 EPY52245.1 - 0.014 14.9 0.1 6 6.4 0.0 2.2 2 0 0 2 2 2 0 TFIIE alpha subunit Herpes_U47 PF05467.6 EPY52245.1 - 0.021 12.6 0.4 0.26 9.0 0.1 1.9 1 1 0 2 2 2 0 Herpesvirus glycoprotein U47 Tautomerase PF01361.16 EPY52245.1 - 0.022 14.3 0.0 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Tautomerase enzyme DUF148 PF02520.12 EPY52245.1 - 0.036 13.8 0.9 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 PRANC PF09372.5 EPY52245.1 - 0.04 13.8 0.4 8.4 6.4 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Ribosomal_L20 PF00453.13 EPY52245.1 - 0.042 13.7 0.0 13 5.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L20 Sec63 PF02889.11 EPY52245.1 - 0.049 12.8 0.1 6.1 5.9 0.0 2.0 1 1 0 2 2 2 0 Sec63 Brl domain Dak2 PF02734.12 EPY52245.1 - 0.072 12.7 0.1 11 5.6 0.0 2.1 1 1 1 2 2 2 0 DAK2 domain GPI-anchored PF10342.4 EPY52247.1 - 2.4e-11 43.9 3.1 2.9e-11 43.6 2.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family YpzI PF14140.1 EPY52251.1 - 0.0046 16.4 0.8 3.5 7.2 0.1 2.5 2 0 0 2 2 2 2 YpzI-like protein PBD PF00786.23 EPY52251.1 - 0.019 15.4 0.3 11 6.5 0.0 2.7 2 0 0 2 2 2 0 P21-Rho-binding domain Bul1_N PF04425.7 EPY52251.1 - 0.052 12.1 1.1 4.8 5.6 0.1 2.1 2 0 0 2 2 2 0 Bul1 N terminus MFS_1 PF07690.11 EPY52252.1 - 7.2e-15 54.5 7.8 7.2e-15 54.5 5.4 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY52252.1 - 1e-06 27.6 8.3 1e-06 27.6 5.8 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPY52253.1 - 1e-42 146.1 47.3 1e-42 146.1 32.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPY52253.1 - 1.8e-22 79.3 12.4 3.5e-22 78.3 8.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPY52253.1 - 7.2e-18 64.3 1.0 7.2e-18 64.3 0.7 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY52254.1 - 2.3e-35 121.9 33.7 2.3e-35 121.9 23.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4179 PF13786.1 EPY52254.1 - 4.1 7.6 5.2 2.8 8.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) MUG2_C PF08593.5 EPY52255.1 - 1.9e-08 34.3 0.2 5.3e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal EcoR124_C PF12008.3 EPY52255.1 - 0.013 14.7 0.3 0.64 9.1 0.0 2.3 2 1 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Nudc_N PF14050.1 EPY52255.1 - 0.06 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. DUF677 PF05055.7 EPY52255.1 - 0.091 11.4 0.3 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3467 PF11950.3 EPY52256.1 - 0.045 13.7 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) DUF226 PF02890.9 EPY52256.1 - 0.073 12.8 0.5 0.14 11.9 0.3 1.6 1 1 1 2 2 2 0 Borrelia family of unknown function DUF226 Oxidored_FMN PF00724.15 EPY52257.1 - 4.9e-105 351.2 0.0 5.7e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GST_N PF02798.15 EPY52258.1 - 6.8e-17 61.4 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPY52258.1 - 3e-15 55.9 0.0 5.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPY52258.1 - 1e-12 48.0 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPY52258.1 - 0.12 12.2 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Asparaginase PF00710.15 EPY52259.1 - 5.9e-68 229.0 1.8 7e-68 228.7 1.2 1.1 1 0 0 1 1 1 1 Asparaginase Glyco_hydro_72 PF03198.9 EPY52261.1 - 3e-44 151.2 2.2 5.1e-44 150.5 1.5 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPY52261.1 - 8.6e-07 29.3 1.1 2e-06 28.1 0.4 2.0 1 1 1 2 2 2 1 X8 domain RTA1 PF04479.8 EPY52262.1 - 0.027 13.9 0.9 0.038 13.4 0.6 1.1 1 0 0 1 1 1 0 RTA1 like protein TauD PF02668.11 EPY52264.1 - 7.2e-19 68.4 0.0 7.9e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ARID PF01388.16 EPY52265.1 - 0.021 14.6 0.0 12 5.8 0.0 2.8 3 0 0 3 3 3 0 ARID/BRIGHT DNA binding domain Corona_5a PF06336.6 EPY52265.1 - 0.058 13.2 1.0 13 5.7 0.1 2.5 2 0 0 2 2 2 0 Coronavirus 5a protein Sugar_tr PF00083.19 EPY52266.1 - 1.4e-25 89.7 38.3 6.6e-21 74.4 6.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPY52266.1 - 4.1e-18 65.2 42.0 1.3e-14 53.6 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_FMN PF00724.15 EPY52267.1 - 9.9e-108 360.1 0.0 1.1e-107 359.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_binding_8 PF08022.7 EPY52268.1 - 5.8e-28 96.8 0.0 1.2e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPY52268.1 - 2.7e-21 76.1 2.1 5.8e-21 75.0 0.3 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPY52268.1 - 2.8e-11 43.5 7.2 4.4e-11 42.9 4.3 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPY52268.1 - 2.8e-05 24.6 0.0 0.00036 21.0 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2423 PF10338.4 EPY52269.1 - 2.3 8.2 7.4 0.18 11.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) ARID PF01388.16 EPY52272.1 - 0.00053 19.7 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain DUP PF00674.13 EPY52272.1 - 0.0026 17.7 1.8 3.3 7.7 0.1 3.3 3 2 0 3 3 3 2 DUP family Corona_5a PF06336.6 EPY52272.1 - 0.02 14.7 1.0 7.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Coronavirus 5a protein YpzI PF14140.1 EPY52274.1 - 0.005 16.2 0.8 3.6 7.1 0.1 2.5 2 0 0 2 2 2 2 YpzI-like protein Bul1_N PF04425.7 EPY52274.1 - 0.051 12.1 1.1 5 5.5 0.1 2.2 2 0 0 2 2 2 0 Bul1 N terminus PBD PF00786.23 EPY52274.1 - 0.44 10.9 5.6 11 6.5 0.0 3.2 4 0 0 4 4 4 0 P21-Rho-binding domain AA_permease PF00324.16 EPY52275.1 - 3.3e-99 332.3 41.1 4.6e-99 331.9 28.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY52275.1 - 2.3e-26 92.3 48.7 6e-26 90.9 33.8 1.6 1 1 0 1 1 1 1 Amino acid permease bZIP_2 PF07716.10 EPY52276.1 - 2.7e-11 43.1 15.4 4e-11 42.5 10.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EPY52276.1 - 2.1e-07 30.7 9.8 2.1e-07 30.7 6.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor XhlA PF10779.4 EPY52276.1 - 0.00085 19.1 2.1 0.0015 18.3 1.5 1.4 1 0 0 1 1 1 1 Haemolysin XhlA DUF4094 PF13334.1 EPY52276.1 - 0.001 19.3 3.4 0.0032 17.8 2.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4094) CAF-1_p150 PF11600.3 EPY52276.1 - 0.013 14.8 9.3 0.021 14.2 6.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CASP_C PF08172.7 EPY52276.1 - 0.026 13.5 5.5 0.038 13.0 3.8 1.2 1 0 0 1 1 1 0 CASP C terminal TSC22 PF01166.13 EPY52276.1 - 0.04 13.8 1.5 0.052 13.5 0.3 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Fib_alpha PF08702.5 EPY52276.1 - 0.1 12.7 4.9 0.16 12.0 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ndc1_Nup PF09531.5 EPY52276.1 - 0.11 10.8 4.5 0.15 10.4 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cor1 PF04803.7 EPY52276.1 - 0.28 10.9 6.4 0.47 10.2 4.4 1.4 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region SprA-related PF12118.3 EPY52276.1 - 0.32 10.2 6.4 0.37 10.0 4.4 1.1 1 0 0 1 1 1 0 SprA-related family bZIP_Maf PF03131.12 EPY52276.1 - 0.42 10.9 11.5 0.06 13.6 4.7 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor NuA4 PF09340.5 EPY52276.1 - 0.44 10.2 3.7 1.4 8.5 2.6 1.9 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 TMF_DNA_bd PF12329.3 EPY52276.1 - 8.5 6.2 10.0 3.1 7.6 4.8 1.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ecl1 PF12855.2 EPY52277.1 - 0.00025 20.2 11.8 0.00042 19.5 8.0 1.6 1 1 0 1 1 1 1 Life-span regulatory factor zf-C4pol PF14260.1 EPY52277.1 - 0.0024 17.8 3.5 0.0029 17.5 2.4 1.2 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF2116 PF09889.4 EPY52277.1 - 0.15 11.9 1.0 0.19 11.5 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DZR PF12773.2 EPY52277.1 - 0.43 10.4 5.6 0.34 10.7 2.8 1.5 1 1 0 1 1 1 0 Double zinc ribbon PHD PF00628.24 EPY52277.1 - 0.49 10.1 9.3 1.2 8.8 6.4 1.8 1 1 0 1 1 1 0 PHD-finger zf-HIT PF04438.11 EPY52277.1 - 1.7 8.3 8.9 0.11 12.1 2.8 1.5 2 0 0 2 2 2 0 HIT zinc finger OPT PF03169.10 EPY52278.1 - 8.2e-133 444.0 49.4 9.5e-133 443.8 34.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gam PF06064.6 EPY52279.1 - 0.015 15.4 0.4 0.021 14.9 0.3 1.4 1 1 0 1 1 1 0 Host-nuclease inhibitor protein Gam Arginase PF00491.16 EPY52280.1 - 5.8e-25 88.1 0.0 6.8e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0728 PF15092.1 EPY52280.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 MFS_1 PF07690.11 EPY52281.1 - 1.8e-17 63.1 20.0 2.3e-17 62.7 13.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.14 EPY52281.1 - 0.13 12.5 0.5 0.27 11.5 0.3 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box TFIIE-A_C-term PF11521.3 EPY52281.1 - 0.27 11.2 5.2 0.51 10.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha FMN_red PF03358.10 EPY52282.1 - 5.4e-22 77.9 0.0 2.7e-21 75.6 0.0 1.7 1 1 1 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EPY52282.1 - 3.5e-05 23.3 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EPY52282.1 - 0.083 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain CsbD PF05532.7 EPY52283.1 - 0.0013 18.3 0.4 0.0023 17.5 0.3 1.4 1 0 0 1 1 1 1 CsbD-like CRCB PF02537.10 EPY52284.1 - 2.1e-40 137.2 19.1 1.2e-25 89.7 2.9 2.4 2 0 0 2 2 2 2 CrcB-like protein AA_permease PF00324.16 EPY52285.1 - 2.8e-126 421.6 37.6 3.5e-126 421.3 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY52285.1 - 1.5e-35 122.6 38.9 1.8e-35 122.3 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease GST_C PF00043.20 EPY52286.1 - 8.5e-10 38.4 0.2 1.3e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPY52286.1 - 8e-07 29.4 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPY52286.1 - 2.9e-06 27.0 0.0 7.3e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPY52286.1 - 3.3e-06 27.1 0.0 8.7e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPY52286.1 - 1.1e-05 25.5 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.16 EPY52287.1 - 1.4e-17 63.7 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPY52287.1 - 0.1 11.6 0.0 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EPY52287.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase TauD PF02668.11 EPY52288.1 - 3.5e-46 157.9 0.3 5.3e-46 157.3 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sulfatase PF00884.18 EPY52289.1 - 7e-78 261.9 0.0 9e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPY52289.1 - 0.00014 21.2 0.0 0.021 14.1 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPY52289.1 - 0.0005 18.6 0.0 0.0007 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EPY52289.1 - 0.05 13.8 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase EBP PF05241.7 EPY52290.1 - 0.054 12.4 0.0 0.054 12.4 0.0 2.2 2 1 0 2 2 2 0 Emopamil binding protein Plant_all_beta PF10532.4 EPY52290.1 - 0.27 11.3 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Plant specific N-all beta domain MFS_1 PF07690.11 EPY52293.1 - 1.7e-06 27.0 12.0 2.4e-06 26.5 8.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EPY52294.1 - 6.2e-08 31.7 19.9 6.2e-08 31.7 13.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2207 PF09972.4 EPY52296.1 - 0.34 9.4 4.1 0.52 8.8 2.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.6 EPY52296.1 - 0.35 10.1 2.2 0.55 9.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF21 PF01595.15 EPY52296.1 - 1.3 8.2 11.5 6.3 6.0 7.9 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF21 NfeD PF01957.13 EPY52296.1 - 4.3 7.4 12.3 3.5 7.7 6.3 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding GXWXG PF14231.1 EPY52297.1 - 9.3e-24 82.8 0.1 2.1e-23 81.7 0.1 1.6 2 0 0 2 2 2 1 GXWXG protein DUF4334 PF14232.1 EPY52297.1 - 2e-21 75.3 3.2 2.3e-21 75.1 0.4 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4334) DUF3087 PF11286.3 EPY52298.1 - 0.33 10.1 3.1 0.18 11.0 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) FA_desaturase PF00487.19 EPY52298.1 - 0.36 10.2 1.7 1.5 8.1 0.4 1.9 1 1 1 2 2 2 0 Fatty acid desaturase TraG_N PF07916.6 EPY52298.1 - 0.45 8.8 2.8 0.62 8.4 2.0 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF3784 PF12650.2 EPY52298.1 - 0.6 10.0 5.2 8.4 6.4 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) WTF PF03303.8 EPY52298.1 - 1.6 8.0 13.9 5.8 6.2 9.7 1.9 1 1 0 1 1 1 0 WTF protein DUF4282 PF14110.1 EPY52298.1 - 2.8 8.1 13.0 1.7 8.9 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) XK-related PF09815.4 EPY52298.1 - 6.4 5.6 13.2 0.96 8.3 5.8 1.8 1 1 1 2 2 2 0 XK-related protein FA_desaturase PF00487.19 EPY52299.1 - 0.31 10.4 1.7 1 8.7 0.3 1.9 1 1 1 2 2 2 0 Fatty acid desaturase DUF3087 PF11286.3 EPY52299.1 - 0.42 9.8 3.2 0.22 10.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) WTF PF03303.8 EPY52299.1 - 0.5 9.7 12.0 1.7 7.9 8.3 1.9 1 1 0 1 1 1 0 WTF protein TraG_N PF07916.6 EPY52299.1 - 0.51 8.7 2.8 0.71 8.2 2.0 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF3784 PF12650.2 EPY52299.1 - 0.68 9.9 5.2 9.5 6.2 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF4282 PF14110.1 EPY52299.1 - 3.3 7.9 13.0 1.9 8.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) XK-related PF09815.4 EPY52299.1 - 5.1 5.9 14.5 1.2 8.0 5.9 2.0 1 1 1 2 2 2 0 XK-related protein DUF2207 PF09972.4 EPY52299.1 - 8.4 4.8 8.6 3.8 5.9 1.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Arginase PF00491.16 EPY52300.1 - 2.7e-06 26.8 0.0 0.00045 19.5 0.0 2.4 2 1 1 3 3 3 2 Arginase family HSP20 PF00011.16 EPY52301.1 - 3.6e-13 49.2 0.0 4.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family M-factor PF03855.8 EPY52302.1 - 0.00028 20.8 6.2 0.00047 20.0 4.3 1.5 1 1 0 1 1 1 1 M-factor GPI-anchored PF10342.4 EPY52306.1 - 2.8e-11 43.7 2.6 3.6e-11 43.3 1.8 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MUG2_C PF08593.5 EPY52307.1 - 3.5e-16 59.1 0.0 9.2e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal HSBP1 PF06825.7 EPY52307.1 - 1.3 8.6 4.8 7.3 6.2 3.3 2.3 1 1 0 1 1 1 0 Heat shock factor binding protein 1 PspA_IM30 PF04012.7 EPY52307.1 - 8.9 5.5 8.0 1.7 7.9 1.5 2.5 2 1 0 2 2 2 0 PspA/IM30 family Hemerythrin PF01814.18 EPY52308.1 - 4.7e-12 46.2 0.0 6.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_4C PF11975.3 EPY52308.1 - 0.0047 16.7 0.6 0.0063 16.3 0.4 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain NAAA-beta PF15508.1 EPY52308.1 - 0.087 13.1 0.2 0.83 10.0 0.1 2.2 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HSP20 PF00011.16 EPY52309.1 - 4.9e-22 77.7 0.5 6.1e-22 77.4 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY52309.1 - 0.023 15.2 0.5 0.05 14.1 0.1 1.7 2 0 0 2 2 2 0 CS domain DUF4097 PF13349.1 EPY52309.1 - 0.028 13.9 0.3 0.038 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) DUF562 PF04763.7 EPY52310.1 - 0.013 14.7 0.1 0.041 13.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF562) DUF397 PF04149.7 EPY52310.1 - 0.15 11.7 0.1 0.36 10.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF397) D-ser_dehydrat PF14031.1 EPY52311.1 - 3.7e-22 78.3 0.0 8.8e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EPY52311.1 - 6.8e-11 42.1 0.0 9.1e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TauD PF02668.11 EPY52312.1 - 2.7e-43 148.4 0.0 3.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 EPY52313.1 - 3.1e-43 148.3 0.0 3.9e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EPY52314.1 - 1.7e-42 145.4 78.4 2e-36 125.4 33.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY52314.1 - 0.00017 20.2 13.3 0.00017 20.2 9.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 EPY52314.1 - 0.062 11.4 10.2 0.25 9.4 2.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF1218 PF06749.7 EPY52314.1 - 4.2 7.8 14.0 0.15 12.5 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Arginase PF00491.16 EPY52315.1 - 3.1e-12 46.3 0.0 3.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family VIT1 PF01988.14 EPY52316.1 - 1.5e-06 27.8 0.0 1.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 VIT family DUF606 PF04657.8 EPY52316.1 - 0.08 13.0 0.1 0.096 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF606 FAD_binding_8 PF08022.7 EPY52317.1 - 1.2e-29 102.2 0.1 2.6e-28 97.9 0.0 3.0 3 1 0 3 3 3 1 FAD-binding domain NAD_binding_6 PF08030.7 EPY52317.1 - 9.3e-15 54.8 0.4 8.6e-14 51.7 0.0 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPY52317.1 - 2e-12 47.3 7.1 5.3e-12 45.9 4.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component MUG2_C PF08593.5 EPY52318.1 - 2.3e-08 34.1 0.3 4.3e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal DUF2414 PF10309.4 EPY52318.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Apolipoprotein PF01442.13 EPY52319.1 - 0.034 13.6 0.2 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Sugar_tr PF00083.19 EPY52320.1 - 1.2e-110 370.2 27.3 1.4e-110 370.0 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY52320.1 - 7.4e-15 54.5 26.7 3.1e-09 36.0 6.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EPY52320.1 - 0.0022 16.8 2.0 0.0037 16.0 1.2 1.5 1 1 0 1 1 1 1 BT1 family Zip PF02535.17 EPY52320.1 - 0.69 8.8 8.9 2.7 6.9 3.2 2.6 3 0 0 3 3 3 0 ZIP Zinc transporter Ecl1 PF12855.2 EPY52321.1 - 5.5e-06 25.5 0.6 9.2e-06 24.8 0.4 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-ribbon_3 PF13248.1 EPY52321.1 - 0.041 13.0 0.1 0.07 12.3 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF2116 PF09889.4 EPY52321.1 - 0.046 13.5 1.5 0.049 13.4 0.3 1.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-MYND PF01753.13 EPY52321.1 - 0.081 12.8 0.2 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 MYND finger zf-P11 PF03854.9 EPY52321.1 - 0.47 9.9 0.0 0.47 9.9 0.0 2.1 2 1 0 2 2 2 0 P-11 zinc finger Ecl1 PF12855.2 EPY52322.1 - 5.5e-06 25.5 0.6 9.2e-06 24.8 0.4 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-ribbon_3 PF13248.1 EPY52322.1 - 0.041 13.0 0.1 0.07 12.3 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF2116 PF09889.4 EPY52322.1 - 0.046 13.5 1.5 0.049 13.4 0.3 1.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-MYND PF01753.13 EPY52322.1 - 0.081 12.8 0.2 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 MYND finger zf-P11 PF03854.9 EPY52322.1 - 0.47 9.9 0.0 0.47 9.9 0.0 2.1 2 1 0 2 2 2 0 P-11 zinc finger MFS_1 PF07690.11 EPY52323.1 - 4.2e-49 167.1 30.9 4.2e-49 167.1 21.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY52323.1 - 1.2e-07 30.6 29.0 3.3e-07 29.2 20.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_8 PF08022.7 EPY52324.1 - 4.6e-25 87.5 1.2 7.2e-25 86.9 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EPY52324.1 - 7.7e-18 64.8 0.2 2.2e-17 63.4 0.1 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPY52324.1 - 2.5e-13 50.2 15.3 2.7e-13 50.0 7.2 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPY52324.1 - 0.026 15.1 0.0 0.11 13.0 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain MFS_1 PF07690.11 EPY52325.1 - 1.6e-23 82.9 39.1 3.4e-20 72.0 27.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPY52325.1 - 7.9e-09 34.2 22.9 1.5e-08 33.3 15.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 EPY52325.1 - 0.017 14.9 3.5 0.04 13.7 0.1 2.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) YtpI PF14007.1 EPY52325.1 - 5.2 7.0 16.9 0.97 9.3 1.0 3.8 3 0 0 3 3 3 0 YtpI-like protein Aldo_ket_red PF00248.16 EPY52326.1 - 7.6e-66 221.8 0.0 8.6e-66 221.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_3 PF01596.12 EPY52327.1 - 1.4e-17 63.3 0.1 4.7e-17 61.7 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_24 PF13578.1 EPY52327.1 - 6.9e-10 39.7 0.0 1.2e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY52327.1 - 9.4e-05 22.9 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY52327.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 EPY52327.1 - 0.023 13.9 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Peptidase_C26 PF07722.8 EPY52328.1 - 3.4e-45 154.1 0.0 4.3e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EPY52328.1 - 6.8e-12 45.2 0.1 9.3e-12 44.7 0.1 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_5 PF13507.1 EPY52328.1 - 0.00092 18.1 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.9 EPY52328.1 - 0.046 13.2 0.5 1.8 8.1 0.1 2.6 2 1 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain Helicase_C PF00271.26 EPY52329.1 - 1.5e-09 37.5 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 EPY52329.1 - 6.2e-09 35.1 1.3 6.2e-08 31.9 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal DEAD PF00270.24 EPY52329.1 - 0.016 14.6 0.0 0.045 13.2 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase bPH_3 PF14470.1 EPY52329.1 - 0.085 13.1 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial PH domain AAA_14 PF13173.1 EPY52329.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain VWA_2 PF13519.1 EPY52330.1 - 1.1e-11 45.1 0.0 1.5e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EPY52330.1 - 3e-08 33.4 0.0 4.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EPY52330.1 - 0.00022 20.9 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EPY52330.1 - 0.0064 15.9 2.0 0.019 14.4 1.4 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Glycos_transf_1 PF00534.15 EPY52330.1 - 0.0075 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 XPC-binding PF09280.6 EPY52330.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 XPC-binding domain RNase_T PF00929.19 EPY52331.1 - 1.6e-27 96.7 0.1 4e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 Exonuclease SR-25 PF10500.4 EPY52331.1 - 0.0023 17.4 14.9 0.0023 17.4 10.3 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Vfa1 PF08432.5 EPY52331.1 - 0.0077 16.2 13.2 0.0077 16.2 9.1 2.6 3 0 0 3 3 3 1 AAA-ATPase Vps4-associated protein 1 DNA_pol_A_exo1 PF01612.15 EPY52331.1 - 0.011 15.2 0.4 0.062 12.7 0.0 2.3 2 1 0 2 2 2 0 3'-5' exonuclease Peptidase_C37 PF05416.7 EPY52331.1 - 0.05 11.8 6.2 0.081 11.2 4.3 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase ParA PF10609.4 EPY52332.1 - 2.8e-37 126.4 0.1 6.6e-37 125.2 0.1 1.6 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EPY52332.1 - 1.6e-15 57.0 0.0 2.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EPY52332.1 - 8.8e-07 28.2 0.5 3.3e-05 23.0 0.1 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 EPY52332.1 - 6.2e-06 25.4 0.0 1.1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EPY52332.1 - 3.9e-05 23.3 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 EPY52332.1 - 7.5e-05 22.7 0.0 0.0006 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPY52332.1 - 0.0042 16.5 0.0 0.0093 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPY52332.1 - 0.006 15.7 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SIS_2 PF13580.1 EPY52332.1 - 0.0073 16.0 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 1 SIS domain Fer4_NifH PF00142.13 EPY52332.1 - 0.019 14.1 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 EPY52332.1 - 0.041 12.7 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.17 EPY52332.1 - 0.057 12.8 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EPY52332.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY52332.1 - 0.18 11.6 0.0 0.67 9.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.7 EPY52333.1 - 9.3e-187 621.7 0.0 1.1e-186 621.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glyco_transf_34 PF05637.7 EPY52334.1 - 6.3e-73 245.2 1.3 7.6e-73 244.9 0.9 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ATP-synt_ab PF00006.20 EPY52335.1 - 1.3e-58 198.0 0.0 1.7e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPY52335.1 - 2.6e-16 60.0 0.0 4.6e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPY52335.1 - 3.4e-10 39.9 0.7 8.3e-10 38.7 0.2 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain TPR_11 PF13414.1 EPY52336.1 - 3.1e-14 52.3 12.0 4.5e-06 26.2 1.9 4.8 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 EPY52336.1 - 4.5e-13 49.4 1.3 5.4e-05 23.7 2.7 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52336.1 - 9.1e-11 40.8 15.1 0.018 14.8 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52336.1 - 3.8e-09 36.7 5.0 0.032 14.5 0.0 5.0 4 1 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EPY52336.1 - 1.3e-05 25.2 15.1 0.006 16.6 0.3 6.3 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPY52336.1 - 1.5e-05 25.1 6.7 0.3 11.8 0.0 6.5 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPY52336.1 - 4.9e-05 22.7 16.5 0.21 11.2 0.1 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52336.1 - 0.00011 22.1 1.5 6.6 7.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPY52336.1 - 0.0019 17.8 7.7 1.9 8.4 0.1 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPY52336.1 - 0.0081 16.0 7.8 2.3 8.1 0.0 5.7 6 1 1 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat DUF1041 PF06292.12 EPY52336.1 - 0.014 15.5 0.1 0.057 13.5 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) DUF1040 PF06288.8 EPY52336.1 - 0.055 13.7 0.1 0.53 10.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) DUF627 PF04781.7 EPY52336.1 - 0.11 12.1 2.2 0.18 11.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_9 PF13371.1 EPY52336.1 - 0.46 10.3 7.5 4.7 7.1 0.0 4.3 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY52336.1 - 3.7 8.2 7.4 64 4.3 0.1 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1774 PF08611.5 EPY52337.1 - 6.2e-23 80.7 3.7 6.2e-23 80.7 2.6 3.2 2 1 1 3 3 3 1 Fungal protein of unknown function (DUF1774) Peptidase_S9 PF00326.16 EPY52338.1 - 9e-05 21.7 0.0 0.016 14.4 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family DUF3152 PF11350.3 EPY52338.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3152) TPR_11 PF13414.1 EPY52339.1 - 2.2e-32 110.4 22.1 4.2e-07 29.5 0.0 11.0 8 3 2 11 11 11 7 TPR repeat TPR_1 PF00515.23 EPY52339.1 - 3.3e-32 108.7 12.9 7.6e-06 25.3 0.1 11.0 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52339.1 - 2.1e-30 102.1 21.4 1.9e-05 24.1 0.1 12.4 14 1 0 14 14 12 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52339.1 - 1.7e-27 95.1 18.0 5e-05 23.1 0.1 9.8 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52339.1 - 7.1e-24 83.9 1.1 0.00088 19.5 0.0 8.8 8 3 4 12 12 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 EPY52339.1 - 5.4e-23 79.0 14.4 0.00016 21.2 0.0 11.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52339.1 - 1.2e-19 69.0 6.5 0.04 14.5 0.0 10.9 8 4 3 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52339.1 - 1.3e-19 70.2 3.9 0.002 18.7 0.0 9.6 7 2 4 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 EPY52339.1 - 3.4e-17 61.6 17.9 0.003 17.8 0.3 10.0 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPY52339.1 - 2.9e-14 51.6 10.9 0.0042 16.7 0.1 9.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52339.1 - 6.7e-11 41.4 9.6 1.7 9.0 0.0 11.2 12 1 0 12 12 12 1 Tetratricopeptide repeat Apc3 PF12895.2 EPY52339.1 - 4.9e-09 36.2 12.3 0.0055 16.8 0.1 6.5 6 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EPY52339.1 - 3.1e-06 26.9 1.8 0.54 10.1 0.0 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPY52339.1 - 5.5e-05 22.9 23.4 0.7 9.9 0.2 8.7 11 0 0 11 11 10 3 Tetratricopeptide repeat CAP_GLY PF01302.20 EPY52340.1 - 8e-21 73.5 0.6 1.5e-20 72.6 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain CDC37_N PF03234.9 EPY52340.1 - 0.0057 16.9 11.0 0.0057 16.9 7.6 5.3 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding But2 PF09792.4 EPY52341.1 - 3.2e-38 130.6 2.9 3.2e-38 130.6 2.0 2.0 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Methyltransf_10 PF05971.7 EPY52342.1 - 7e-07 28.6 0.0 8.6e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_10 PF05971.7 EPY52343.1 - 2.1e-19 69.7 0.1 5e-19 68.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF890) Tnp_P_element PF12017.3 EPY52343.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Transposase protein LSM PF01423.17 EPY52344.1 - 7.4e-19 67.0 0.2 1.1e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPY52344.1 - 0.0036 17.1 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 EPY52344.1 - 0.056 11.9 2.3 0.081 11.4 1.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gemin7 PF11095.3 EPY52344.1 - 0.062 13.0 0.1 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) RNA_pol_Rpb1_R PF05001.8 EPY52344.1 - 1 9.6 3.0 1.5 9.1 2.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat ETF PF01012.16 EPY52345.1 - 3.1e-36 124.5 0.2 6e-36 123.6 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EPY52345.1 - 1.5e-31 107.8 0.1 2.9e-31 106.9 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Cactin_mid PF10312.4 EPY52346.1 - 0.019 14.2 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Conserved mid region of cactin Pterin_4a PF01329.14 EPY52347.1 - 1.4e-29 101.6 0.2 1.5e-29 101.5 0.2 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase TetM_leader PF08076.6 EPY52348.1 - 1.2 8.6 4.4 0.56 9.8 0.9 1.9 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide RRM_2 PF04059.7 EPY52349.1 - 8.6e-52 173.1 0.7 1.6e-51 172.2 0.5 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EPY52349.1 - 6.5e-16 57.7 0.0 7.8e-07 28.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52349.1 - 2.3e-07 30.6 0.0 0.0065 16.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52349.1 - 6.3e-07 29.1 0.2 0.011 15.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRIP PF01465.15 EPY52350.1 - 1.2e-11 43.9 2.5 4.5e-11 42.0 1.7 2.2 1 0 0 1 1 1 1 GRIP domain FliJ PF02050.11 EPY52350.1 - 0.0027 17.7 1.7 0.0027 17.7 1.2 7.0 4 1 4 8 8 8 2 Flagellar FliJ protein RIC1 PF07064.8 EPY52351.1 - 1e-37 130.0 3.6 1.7e-37 129.3 2.5 1.3 1 0 0 1 1 1 1 RIC1 PQQ_3 PF13570.1 EPY52351.1 - 0.015 15.5 0.2 0.14 12.4 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain CK_II_beta PF01214.13 EPY52352.1 - 2.4e-78 261.8 0.0 3.3e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Acyltransferase PF01553.16 EPY52353.1 - 8.4e-32 109.3 0.0 1.1e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Polysacc_synt_3 PF13440.1 EPY52353.1 - 0.033 13.6 0.8 0.082 12.3 0.6 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_11 PF13414.1 EPY52354.1 - 2.9e-37 126.1 18.1 1.2e-09 37.7 0.0 7.4 6 1 1 7 7 7 6 TPR repeat TPR_1 PF00515.23 EPY52354.1 - 2.5e-34 115.4 16.3 3.5e-08 32.7 0.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52354.1 - 9.6e-34 112.5 18.4 6.2e-06 25.7 0.1 11.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_8 PF13181.1 EPY52354.1 - 9.7e-29 96.9 15.2 0.00024 20.6 0.0 9.6 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52354.1 - 3.4e-27 94.1 3.5 4.9e-06 26.3 0.5 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EPY52354.1 - 4.9e-25 87.4 23.0 3e-18 65.7 0.6 6.1 3 1 5 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EPY52354.1 - 2.8e-22 78.7 0.8 6.2e-06 26.4 0.0 6.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52354.1 - 5.6e-19 66.7 5.5 0.002 18.2 0.0 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52354.1 - 6.4e-16 58.5 1.7 0.00011 22.7 0.0 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52354.1 - 3.4e-15 55.1 0.0 0.04 14.5 0.0 8.1 5 1 5 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EPY52354.1 - 3.4e-12 45.9 5.2 0.12 12.9 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY52354.1 - 9.1e-10 37.6 2.0 0.17 11.7 0.0 7.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPY52354.1 - 6.2e-05 22.7 0.8 0.86 9.5 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EPY52354.1 - 0.00048 19.2 2.3 0.66 8.9 0.1 3.4 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPY52354.1 - 0.0032 17.3 0.0 22 5.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EPY52354.1 - 0.013 14.7 0.3 3.3 6.8 0.0 3.0 2 1 1 3 3 3 0 Coatomer epsilon subunit TPR_21 PF09976.4 EPY52354.1 - 0.018 15.0 1.3 0.051 13.5 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat ChAPs PF09295.5 EPY52354.1 - 0.02 13.6 0.1 0.2 10.3 0.0 2.4 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 EPY52354.1 - 0.02 14.7 6.2 0.62 9.9 0.1 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 EPY52354.1 - 0.26 11.9 8.1 3.1 8.5 0.0 4.9 6 0 0 6 6 4 0 Sel1 repeat MIT PF04212.13 EPY52354.1 - 0.46 10.3 5.4 12 5.8 0.0 4.0 3 1 1 4 4 3 0 MIT (microtubule interacting and transport) domain ACPS PF01648.15 EPY52355.1 - 1.2e-10 41.1 0.0 4.5e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily MIF4G PF02854.14 EPY52356.1 - 4.4e-58 196.1 0.1 8.4e-58 195.2 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EPY52356.1 - 3.1e-14 52.6 0.2 3.1e-14 52.6 0.1 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 Fibrinogen_BP PF08017.6 EPY52356.1 - 8.4e-05 20.9 28.5 0.00017 19.9 19.8 1.4 1 0 0 1 1 1 1 Fibrinogen binding protein Med27 PF11571.3 EPY52357.1 - 6.7e-08 32.5 1.8 1e-07 31.9 0.4 1.9 2 0 0 2 2 2 1 Mediator complex subunit 27 FliD_N PF02465.13 EPY52357.1 - 1.1 9.6 5.8 2 8.8 0.5 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Bac_surface_Ag PF01103.18 EPY52358.1 - 5e-50 170.7 0.2 6.2e-50 170.4 0.2 1.1 1 0 0 1 1 1 1 Surface antigen DUF2945 PF11160.3 EPY52359.1 - 2e-08 33.9 0.7 8.3e-07 28.7 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) DUF2551 PF10826.3 EPY52359.1 - 0.079 12.8 0.1 0.089 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) Brix PF04427.13 EPY52360.1 - 2.5e-46 157.7 0.1 3.6e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain adh_short PF00106.20 EPY52361.1 - 9.1e-12 45.2 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY52361.1 - 1.7e-05 24.5 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPY52361.1 - 0.00018 21.5 0.1 0.00047 20.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EPY52361.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPY52361.1 - 0.021 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EPY52361.1 - 0.051 12.8 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family VHS PF00790.14 EPY52362.1 - 4.3e-37 126.8 2.2 2.3e-36 124.4 0.1 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EPY52362.1 - 5.6e-18 64.5 10.8 8.3e-18 64.0 6.2 2.1 2 0 0 2 2 2 1 FYVE zinc finger UIM PF02809.15 EPY52362.1 - 2.1e-08 33.0 6.4 0.0014 18.0 1.2 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EPY52362.1 - 0.0011 18.8 6.4 0.0033 17.3 4.4 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.16 EPY52362.1 - 0.024 14.5 3.4 0.067 13.0 2.3 1.7 1 0 0 1 1 1 0 IBR domain zf-DHHC PF01529.15 EPY52362.1 - 0.95 8.8 6.1 0.84 9.0 2.5 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4338 PF14236.1 EPY52362.1 - 8.5 4.9 6.1 5.2 5.6 2.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4338) p450 PF00067.17 EPY52363.1 - 4.1e-54 183.8 0.0 5.1e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ComX PF05952.7 EPY52363.1 - 0.033 13.6 0.0 0.092 12.2 0.0 1.8 1 0 0 1 1 1 0 Bacillus competence pheromone ComX zf-RING_UBOX PF13445.1 EPY52363.1 - 0.063 13.0 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Myotub-related PF06602.9 EPY52364.1 - 1.6e-139 464.5 0.8 2e-139 464.2 0.5 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EPY52364.1 - 0.00049 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EPY52364.1 - 0.0015 18.1 0.1 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EPY52364.1 - 0.0094 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Cut8_C PF08559.5 EPY52364.1 - 0.12 12.2 1.3 2.4 7.9 0.3 2.4 2 0 0 2 2 2 0 Cut8 six-helix bundle PH PF00169.24 EPY52365.1 - 6.7e-06 26.2 0.1 3.6e-05 23.8 0.1 2.3 1 1 0 1 1 1 1 PH domain Sec7 PF01369.15 EPY52366.1 - 1.8e-36 125.6 3.1 4e-36 124.4 2.2 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EPY52366.1 - 3.1e-05 24.0 0.1 0.00054 20.1 0.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain DUF16 PF01519.11 EPY52366.1 - 0.015 15.5 1.1 0.066 13.4 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 IncA PF04156.9 EPY52366.1 - 0.32 10.5 4.2 0.89 9.1 2.5 2.0 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 EPY52366.1 - 0.32 9.3 3.5 0.61 8.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PHF5 PF03660.9 EPY52367.1 - 4.1e-49 165.0 12.1 4.7e-49 164.9 8.4 1.0 1 0 0 1 1 1 1 PHF5-like protein Fer4_8 PF13183.1 EPY52367.1 - 1.3 9.0 16.4 1.1 9.3 0.2 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain DZR PF12773.2 EPY52367.1 - 5.7 6.8 17.5 89 3.0 12.2 2.5 1 1 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.8 EPY52367.1 - 8.1 3.9 7.8 8.5 3.8 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DDE_1 PF03184.14 EPY52368.1 - 2.9e-60 203.1 1.1 5.6e-60 202.1 0.3 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPY52368.1 - 5.6e-15 54.8 0.3 1.8e-14 53.2 0.2 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain NPR2 PF06218.6 EPY52369.1 - 7.4e-140 466.4 11.2 8.6e-138 459.6 7.8 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EPY52369.1 - 0.0015 17.1 3.0 0.74 8.2 0.0 3.0 2 1 1 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 WD40 PF00400.27 EPY52371.1 - 4e-16 58.1 11.8 2.5e-07 30.2 1.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EPY52371.1 - 1.7e-05 24.6 0.3 0.02 14.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Lactamase_B_4 PF13691.1 EPY52371.1 - 0.043 13.2 0.6 5.8 6.4 0.0 3.1 2 1 1 3 3 3 0 tRNase Z endonuclease Cytochrom_D1 PF02239.11 EPY52371.1 - 0.076 11.2 0.0 1.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Adaptin_N PF01602.15 EPY52372.1 - 5.7e-114 381.3 5.1 7.3e-114 380.9 3.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPY52372.1 - 8.3e-13 48.4 0.2 3.5e-06 27.2 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EPY52372.1 - 1.3e-09 38.1 3.3 7.3e-07 29.2 0.1 4.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EPY52372.1 - 1.8e-09 36.8 3.2 0.046 13.8 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EPY52372.1 - 0.00018 21.8 5.1 0.51 10.9 0.2 5.2 4 1 2 6 6 6 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EPY52372.1 - 0.00025 20.9 0.0 0.17 11.8 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 EPY52372.1 - 0.1 12.4 2.9 4.5 7.2 0.1 4.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CDC45 PF02724.9 EPY52372.1 - 0.74 7.7 12.4 1.1 7.2 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S14 PF00253.16 EPY52373.1 - 1.3e-19 69.2 2.3 1.2e-18 66.2 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e WD40 PF00400.27 EPY52374.1 - 5.8e-17 60.8 2.2 4.1e-05 23.2 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Beta_elim_lyase PF01212.16 EPY52375.1 - 7.6e-78 261.5 0.0 1.3e-77 260.7 0.0 1.3 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPY52375.1 - 0.0087 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EPY52375.1 - 0.043 12.7 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPY52375.1 - 0.056 11.7 0.0 0.08 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SWIRM PF04433.12 EPY52376.1 - 3.1e-34 116.9 0.0 6.7e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EPY52376.1 - 3.3e-09 36.6 0.1 6.6e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY52376.1 - 2.8e-08 33.7 0.0 1e-07 31.9 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EPY52376.1 - 0.0036 16.7 8.6 0.0072 15.8 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Zn_ribbon_2 PF12674.2 EPY52376.1 - 0.02 15.2 0.6 0.062 13.6 0.4 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF164 PF02591.10 EPY52376.1 - 0.083 12.7 0.6 0.18 11.6 0.4 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain SKN1 PF03935.10 EPY52377.1 - 1.8e-230 765.3 3.4 2.2e-230 765.0 2.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Mit_KHE1 PF10173.4 EPY52378.1 - 9.2e-45 152.7 0.2 1.2e-44 152.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related G-alpha PF00503.15 EPY52379.1 - 3.3e-104 348.6 6.5 3.8e-104 348.4 4.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPY52379.1 - 2.6e-13 49.5 0.5 1.2e-08 34.3 0.1 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY52379.1 - 0.0024 17.0 3.8 0.42 9.7 0.2 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region mTERF PF02536.9 EPY52379.1 - 0.021 13.4 0.5 0.77 8.2 0.1 2.4 2 0 0 2 2 2 0 mTERF AAA_29 PF13555.1 EPY52379.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 EPY52379.1 - 0.045 13.3 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein GTP_EFTU PF00009.22 EPY52379.1 - 0.073 12.4 0.1 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Avl9 PF09794.4 EPY52380.1 - 8.9e-118 393.0 0.2 1.1e-117 392.7 0.1 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EPY52380.1 - 1.5e-07 30.9 0.9 0.02 14.1 0.2 3.0 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 EPY52380.1 - 6.9e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking JmjC PF02373.17 EPY52382.1 - 4.3e-19 68.8 0.2 1.4e-18 67.2 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EPY52382.1 - 1e-13 51.3 0.6 5.1e-13 49.1 0.4 1.9 1 1 0 1 1 1 1 Cupin-like domain Bombinin PF05298.6 EPY52382.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bombinin GPI PF06560.6 EPY52382.1 - 0.098 11.6 0.0 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) DUF1649 PF07855.7 EPY52383.1 - 7.5e-23 80.9 0.0 8.8e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Peptidase_C78 PF07910.8 EPY52384.1 - 3e-39 134.4 0.0 3.5e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 DUF1183 PF06682.7 EPY52385.1 - 0.00023 20.9 0.3 0.0003 20.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Tetraspannin PF00335.15 EPY52385.1 - 0.051 12.8 0.7 1.1 8.4 0.3 2.1 2 0 0 2 2 2 0 Tetraspanin family CAF1C_H4-bd PF12265.3 EPY52386.1 - 1.4e-20 72.9 0.0 2.6e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 EPY52386.1 - 7.9e-09 35.0 12.4 1.8e-05 24.4 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF2611 PF11022.3 EPY52387.1 - 7.7e-18 64.3 0.0 8.5e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) SR-25 PF10500.4 EPY52388.1 - 0.14 11.6 3.6 0.16 11.4 2.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pinin_SDK_memA PF04696.8 EPY52388.1 - 0.43 10.1 6.6 0.57 9.7 4.6 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF1620 PF07774.8 EPY52389.1 - 7.7e-65 218.1 2.0 8.2e-65 218.0 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EPY52389.1 - 0.00014 21.4 0.0 0.0034 16.8 0.0 2.7 2 1 1 3 3 3 1 PQQ-like domain WD40 PF00400.27 EPY52390.1 - 3.6e-47 156.6 11.1 3.5e-10 39.3 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EPY52390.1 - 5.1e-06 26.3 0.1 0.00085 19.0 0.1 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPY52390.1 - 0.0038 15.1 0.1 0.0068 14.2 0.0 1.3 1 0 0 1 1 1 1 IKI3 family Nup160 PF11715.3 EPY52390.1 - 0.033 12.3 0.0 0.072 11.2 0.0 1.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 UPF0047 PF01894.12 EPY52391.1 - 1.7e-42 143.9 0.0 2e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Alpha-amylase PF00128.19 EPY52392.1 - 5.4e-60 203.4 0.0 7e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPY52392.1 - 1e-14 54.3 0.0 1.2e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) PP2C PF00481.16 EPY52393.1 - 4.9e-42 144.0 0.0 2.4e-40 138.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPY52393.1 - 0.018 14.7 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Peptidase_S8 PF00082.17 EPY52394.1 - 4.1e-56 190.1 15.0 6.4e-56 189.5 10.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPY52394.1 - 6.9e-13 48.9 0.5 1.5e-12 47.9 0.3 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF2713 PF10897.3 EPY52394.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) CW_binding_2 PF04122.7 EPY52394.1 - 0.27 11.4 2.9 0.34 11.1 0.2 2.6 4 0 0 4 4 4 0 Putative cell wall binding repeat 2 Myosin_head PF00063.16 EPY52395.1 - 6.2e-242 804.5 3.0 6.2e-242 804.5 2.1 2.3 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 EPY52395.1 - 3e-06 26.8 0.1 6.4e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain TPR_MLP1_2 PF07926.7 EPY52395.1 - 0.0049 16.6 6.8 0.0049 16.6 4.7 10.9 4 3 4 9 9 9 2 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EPY52395.1 - 0.0051 16.7 11.3 0.0051 16.7 7.8 12.3 7 3 7 14 14 14 2 Afadin- and alpha -actinin-Binding AAA_19 PF13245.1 EPY52395.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EPY52395.1 - 0.07 13.2 0.0 0.07 13.2 0.0 4.9 4 1 0 4 4 4 0 AAA domain Abhydrolase_3 PF07859.8 EPY52396.1 - 1e-29 103.6 0.0 5.5e-20 71.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EPY52396.1 - 3.9e-10 38.9 0.1 4.3e-09 35.5 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DUF2235 PF09994.4 EPY52396.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DAGK_cat PF00781.19 EPY52397.1 - 9.5e-27 92.9 0.0 1.4e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain tRNA-synt_1 PF00133.17 EPY52398.1 - 2.6e-151 504.6 0.0 2.5e-150 501.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPY52398.1 - 1.5e-19 70.3 0.4 4.3e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPY52398.1 - 5.3e-19 68.1 6.2 6e-09 35.0 0.1 3.2 2 2 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EPY52398.1 - 1.5e-05 24.3 0.0 0.018 14.3 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EPY52398.1 - 0.00063 18.9 0.0 0.072 12.2 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 EPY52398.1 - 0.00069 18.8 0.1 0.048 12.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1d PF00750.14 EPY52398.1 - 0.0013 17.6 0.0 0.019 13.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) Val_tRNA-synt_C PF10458.4 EPY52398.1 - 0.012 15.6 0.9 0.035 14.1 0.7 1.8 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1c PF00749.16 EPY52398.1 - 0.073 11.7 0.2 0.32 9.6 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain cwf21 PF08312.7 EPY52399.1 - 5e-10 39.0 11.1 2.1e-09 37.0 7.7 2.1 1 1 0 1 1 1 1 cwf21 domain SPATA25 PF15218.1 EPY52399.1 - 0.55 9.6 2.5 0.85 9.0 1.8 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 DUF676 PF05057.9 EPY52400.1 - 9.9e-57 191.7 0.0 1.6e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EPY52400.1 - 7.3e-05 22.5 0.1 0.00013 21.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPY52400.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein ketoacyl-synt PF00109.21 EPY52401.1 - 2e-19 70.0 0.0 4.4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EPY52401.1 - 1.3e-17 63.6 0.0 2.7e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EPY52401.1 - 1.4e-08 34.5 0.0 3.4e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EPY52401.1 - 2.3e-06 27.6 0.0 4.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY52401.1 - 0.0023 17.6 0.0 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 KR domain PP-binding PF00550.20 EPY52401.1 - 0.037 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site LRR_4 PF12799.2 EPY52402.1 - 1.1e-39 133.4 41.1 4.7e-09 35.6 0.3 7.1 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPY52402.1 - 6.4e-23 80.2 39.6 2.1e-06 27.3 2.2 6.1 2 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 EPY52402.1 - 2.8e-14 53.0 30.4 1.3e-07 31.3 1.6 3.9 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.28 EPY52402.1 - 2.2e-11 42.1 41.2 0.047 13.7 0.2 11.6 11 1 1 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.1 EPY52402.1 - 1.1e-09 37.3 28.6 0.77 10.0 0.4 10.0 7 1 2 9 9 9 4 Leucine Rich repeat LRR_7 PF13504.1 EPY52402.1 - 6.3e-08 31.5 30.9 0.22 11.8 0.0 10.4 10 1 1 11 11 11 3 Leucine rich repeat DUF2322 PF10084.4 EPY52402.1 - 0.00033 20.3 0.8 16 5.2 0.0 4.5 3 1 2 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2322) Proteasome PF00227.21 EPY52403.1 - 6.8e-46 155.9 0.2 8.3e-46 155.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pribosyltran_N PF13793.1 EPY52404.1 - 7.6e-42 141.7 0.1 8.2e-41 138.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPY52404.1 - 5.4e-35 120.8 0.1 3.4e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPY52404.1 - 0.0099 15.5 0.1 0.33 10.6 0.1 2.6 3 0 0 3 3 3 1 Phosphoribosyl transferase domain PNP_UDP_1 PF01048.15 EPY52404.1 - 0.023 13.6 0.1 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Phosphorylase superfamily Profilin PF00235.14 EPY52405.1 - 1.8e-38 131.3 0.0 2e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Profilin eIF-3c_N PF05470.7 EPY52406.1 - 4.7e-215 715.2 9.2 3.9e-171 570.1 1.3 4.1 2 2 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EPY52406.1 - 3.3e-13 49.8 0.1 1.9e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain Sec20 PF03908.8 EPY52407.1 - 0.093 12.4 0.2 0.099 12.3 0.1 1.1 1 0 0 1 1 1 0 Sec20 Pkinase PF00069.20 EPY52408.1 - 1.7e-49 168.3 0.1 1.2e-48 165.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52408.1 - 2.2e-19 69.5 0.0 3.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY52408.1 - 0.00058 19.6 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPY52408.1 - 0.017 14.4 0.0 0.037 13.3 0.0 1.6 1 1 0 1 1 1 0 RIO1 family DUF947 PF06102.7 EPY52409.1 - 2.1e-49 167.5 32.1 2.1e-49 167.5 22.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF947) SNARE PF05739.14 EPY52410.1 - 2.1e-18 65.7 2.8 2.1e-18 65.7 2.0 2.8 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EPY52410.1 - 5e-05 23.4 4.9 5e-05 23.4 3.4 3.1 1 1 1 2 2 2 1 Syntaxin DUF3095 PF11294.3 EPY52410.1 - 0.03 13.3 3.9 0.045 12.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) MeMO_Hyd_G PF02964.11 EPY52410.1 - 0.086 12.7 0.7 0.74 9.7 0.1 2.3 2 0 0 2 2 2 0 Methane monooxygenase, hydrolase gamma chain Ribosomal_L3 PF00297.17 EPY52410.1 - 0.14 11.5 6.6 14 4.9 4.5 2.1 1 1 0 1 1 1 0 Ribosomal protein L3 DUF3206 PF11472.3 EPY52411.1 - 0.22 11.2 2.4 0.11 12.2 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) Bromo_TP PF07524.8 EPY52412.1 - 2.4e-19 68.8 0.1 3.7e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF1253 PF06862.7 EPY52412.1 - 0.11 10.9 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Per1 PF04080.8 EPY52414.1 - 1.1e-92 310.2 15.7 1.6e-92 309.7 10.9 1.2 1 0 0 1 1 1 1 Per1-like DEAD PF00270.24 EPY52415.1 - 7.2e-48 162.2 0.0 1.2e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY52415.1 - 3.3e-26 90.9 0.0 8.8e-26 89.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY52415.1 - 7.9e-08 32.3 0.0 5.7e-07 29.5 0.0 2.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Asparaginase_2 PF01112.13 EPY52416.1 - 3.2e-25 88.5 0.1 1.2e-24 86.6 0.1 1.8 1 1 0 1 1 1 1 Asparaginase Mito_carr PF00153.22 EPY52417.1 - 6.3e-58 192.4 0.3 7.6e-19 67.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.16 EPY52418.1 - 7.6e-15 54.7 4.7 2e-14 53.4 2.8 2.1 1 1 1 2 2 2 1 PAP2 superfamily Clathrin PF00637.15 EPY52419.1 - 2.9e-10 39.8 6.7 1.6e-08 34.2 0.1 3.5 4 0 0 4 4 4 2 Region in Clathrin and VPS DUF4119 PF13494.1 EPY52419.1 - 0.028 14.3 0.3 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) zf-rbx1 PF12678.2 EPY52419.1 - 0.1 12.6 2.7 0.26 11.4 1.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPY52419.1 - 0.3 11.1 8.3 0.77 9.8 5.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY52419.1 - 0.76 9.6 8.3 2.4 8.0 5.7 1.9 1 0 0 1 1 1 0 Ring finger domain She9_MDM33 PF05546.6 EPY52420.1 - 5.2e-75 251.5 13.4 7.5e-75 251.0 9.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EPY52420.1 - 0.06 12.9 0.6 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein ResIII PF04851.10 EPY52420.1 - 5.7 6.7 8.8 0.47 10.2 0.5 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit HAD PF12710.2 EPY52421.1 - 1.9e-16 60.8 0.0 2.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPY52421.1 - 3.1e-09 36.3 0.0 9.2e-09 34.8 0.0 1.6 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 EPY52421.1 - 3.2e-08 34.0 0.0 2.2e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY52421.1 - 0.00047 20.6 0.0 0.015 15.7 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.23 EPY52422.1 - 1.9e-43 148.1 2.9 2.5e-43 147.8 2.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EPY52423.1 - 8.5e-15 53.9 5.1 1.2e-08 34.4 0.1 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat CNH PF00780.17 EPY52423.1 - 0.00029 20.3 0.6 0.56 9.5 0.0 2.4 1 1 0 2 2 2 2 CNH domain eIF2A PF08662.6 EPY52423.1 - 0.0016 18.1 0.1 0.031 13.9 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EPY52423.1 - 0.004 16.6 0.0 3.1 7.3 0.0 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.1 EPY52423.1 - 0.0066 16.0 0.2 0.93 9.1 0.0 2.7 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.1 EPY52423.1 - 0.058 13.1 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1212 PF06738.7 EPY52426.1 - 1.6e-49 168.0 10.7 2.8e-46 157.4 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPY52426.1 - 6.1e-23 81.1 8.4 6.1e-23 81.1 5.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Sec39 PF08314.6 EPY52427.1 - 1.1e-81 274.8 22.6 1.7e-81 274.2 15.6 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 GARS_C PF02843.11 EPY52427.1 - 0.24 11.6 0.0 0.48 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Ku_PK_bind PF08785.6 EPY52427.1 - 0.32 10.8 4.4 1.2 8.9 0.3 2.7 2 1 0 2 2 2 0 Ku C terminal domain like V-ATPase_H_N PF03224.9 EPY52428.1 - 7.1e-55 186.3 1.4 1.8e-54 185.0 0.5 2.0 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EPY52428.1 - 1.2e-42 144.5 1.2 2.9e-42 143.3 0.1 2.2 2 1 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.17 EPY52428.1 - 0.00015 21.5 0.0 0.063 13.3 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 EPY52428.1 - 0.0015 18.7 0.0 0.035 14.3 0.0 2.5 2 1 1 3 3 3 1 HEAT repeats Arm PF00514.18 EPY52428.1 - 0.0075 16.0 0.0 0.038 13.8 0.0 2.3 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EPY52428.1 - 0.023 13.8 1.2 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 Armadillo-like CTNNBL PF08216.6 EPY52428.1 - 0.05 13.1 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Steroid_dh PF02544.11 EPY52429.1 - 4.4e-07 29.7 5.6 4.4e-07 29.7 3.9 2.3 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Thioredoxin PF00085.15 EPY52430.1 - 6.4e-31 106.1 1.1 7.3e-31 105.9 0.7 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPY52430.1 - 6.5e-09 35.7 0.1 1.6e-08 34.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EPY52430.1 - 8e-09 35.6 0.3 5.9e-08 32.9 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EPY52430.1 - 2.1e-06 27.4 0.2 2.3e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPY52430.1 - 5.5e-06 25.9 0.3 4.4e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 EPY52430.1 - 8.1e-05 22.1 0.1 9.6e-05 21.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EPY52430.1 - 0.00018 21.4 0.1 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EPY52430.1 - 0.0042 16.5 0.1 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EPY52430.1 - 0.0046 16.9 0.2 0.15 12.0 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin ALG3 PF05208.8 EPY52431.1 - 1.1e-131 439.5 30.6 1.3e-131 439.2 21.2 1.0 1 0 0 1 1 1 1 ALG3 protein HAD_2 PF13419.1 EPY52432.1 - 1.3e-19 71.0 0.0 1.7e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPY52432.1 - 3.7e-08 32.9 0.0 4.3e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EPY52432.1 - 5.2e-07 30.2 0.0 0.00025 21.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ATG11 PF10377.4 EPY52433.1 - 1.3e-27 96.2 0.2 1.3e-27 96.2 0.1 2.6 3 0 0 3 3 3 1 Autophagy-related protein 11 Snapin_Pallidin PF14712.1 EPY52433.1 - 0.18 12.1 10.2 0.59 10.4 0.2 4.3 3 0 0 3 3 3 0 Snapin/Pallidin DUF948 PF06103.6 EPY52433.1 - 3.5 7.5 6.8 5.9 6.8 0.1 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ly49 PF08391.5 EPY52433.1 - 5 7.2 13.6 0.77 9.9 1.4 3.5 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region DUF1765 PF08578.5 EPY52434.1 - 5.2e-24 84.6 6.2 5.2e-24 84.6 4.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1765) SH3_1 PF00018.23 EPY52435.1 - 2.1e-12 46.1 0.0 4e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPY52435.1 - 3.8e-11 42.3 0.2 9.8e-11 41.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EPY52435.1 - 2.4e-07 30.1 0.0 4.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EPY52435.1 - 0.00013 22.1 2.4 0.00014 21.9 0.3 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Sugar_tr PF00083.19 EPY52436.1 - 6.7e-111 371.0 24.1 8e-111 370.7 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY52436.1 - 2e-27 95.8 27.1 2e-27 95.8 18.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPY52436.1 - 3.3e-08 32.1 10.5 4.2e-07 28.5 4.2 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPY52436.1 - 0.052 11.6 8.1 0.013 13.6 1.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector 7tm_1 PF00001.16 EPY52437.1 - 0.1 11.7 0.2 0.11 11.6 0.2 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) HMG_CoA_synt_C PF08540.5 EPY52438.1 - 4.3e-108 361.0 0.4 5.4e-108 360.7 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EPY52438.1 - 5.1e-84 280.1 0.6 2.4e-83 277.9 0.2 2.0 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 EPY52438.1 - 0.069 12.4 0.3 0.19 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) RasGAP_C PF03836.10 EPY52439.1 - 3.5e-46 156.4 2.2 1e-45 154.9 1.6 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EPY52439.1 - 4.7e-26 91.6 1.5 4.7e-26 91.6 1.1 2.5 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EPY52439.1 - 1.8e-18 64.3 20.7 0.0015 17.9 0.0 10.0 10 0 0 10 10 10 6 IQ calmodulin-binding motif CH PF00307.26 EPY52439.1 - 6.7e-13 48.6 1.3 7.8e-12 45.2 0.0 3.6 4 1 0 4 4 4 1 Calponin homology (CH) domain PROCN PF08083.6 EPY52440.1 - 1.5e-223 741.6 4.8 2.4e-223 741.0 3.3 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EPY52440.1 - 1.2e-125 417.4 1.2 2.2e-125 416.5 0.9 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EPY52440.1 - 2.8e-91 303.0 1.8 8.7e-91 301.4 1.3 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EPY52440.1 - 1e-75 252.5 1.2 2.3e-75 251.3 0.9 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EPY52440.1 - 5.6e-68 226.7 0.1 1.2e-67 225.7 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EPY52440.1 - 6.8e-43 145.3 0.0 1.6e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EPY52440.1 - 2.4e-41 139.4 0.1 6.4e-41 138.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EPY52440.1 - 1.8e-07 30.8 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WD40 PF00400.27 EPY52441.1 - 1e-29 101.2 21.5 4.5e-09 35.8 0.1 8.6 8 1 1 9 9 9 6 WD domain, G-beta repeat zf-RING_2 PF13639.1 EPY52441.1 - 0.086 12.6 10.0 0.19 11.6 7.0 1.5 1 0 0 1 1 1 0 Ring finger domain RINGv PF12906.2 EPY52441.1 - 0.18 11.9 10.0 0.52 10.3 7.0 1.9 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EPY52441.1 - 0.58 10.2 10.7 1.3 9.1 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CH PF00307.26 EPY52442.1 - 3.3e-11 43.1 0.1 4.3e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain RIG-I_C-RD PF11648.3 EPY52442.1 - 0.0025 17.6 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of RIG-I Hexokinase_2 PF03727.11 EPY52444.1 - 2e-73 246.5 0.0 2.9e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPY52444.1 - 1.6e-68 230.0 0.0 2.5e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF1351 PF07083.6 EPY52444.1 - 0.016 14.8 0.2 0.033 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Ribosom_S12_S23 PF00164.20 EPY52445.1 - 2.3e-46 156.1 2.1 2.7e-46 155.9 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 MRP-L28 PF09812.4 EPY52446.1 - 2.1e-11 43.8 1.1 6.6e-11 42.2 0.8 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 Phage-MuB_C PF09077.6 EPY52446.1 - 0.061 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Brix PF04427.13 EPY52447.1 - 1.2e-40 139.2 0.3 1.7e-40 138.7 0.2 1.2 1 0 0 1 1 1 1 Brix domain Securin PF04856.8 EPY52447.1 - 0.36 10.4 4.1 1.4 8.6 2.8 1.7 2 0 0 2 2 2 0 Securin sister-chromatid separation inhibitor SBDS_C PF09377.5 EPY52448.1 - 1e-38 131.8 0.1 1.7e-38 131.1 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EPY52448.1 - 5.6e-35 119.0 1.8 5.6e-35 119.0 1.3 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein KOW PF00467.24 EPY52449.1 - 1.1e-05 24.9 0.3 2.3e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 KOW motif TFIIIC_delta PF12657.2 EPY52449.1 - 0.11 12.2 0.1 3.5 7.3 0.1 2.2 1 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Snf7 PF03357.16 EPY52450.1 - 1.6e-30 105.7 21.1 1.6e-30 105.7 14.6 1.4 1 1 1 2 2 2 1 Snf7 B12-binding_2 PF02607.12 EPY52450.1 - 0.089 12.8 0.6 0.66 10.0 0.2 2.4 3 0 0 3 3 3 0 B12 binding domain REV PF00424.13 EPY52450.1 - 0.12 12.3 4.5 5.1 7.0 0.0 2.6 1 1 1 2 2 2 0 REV protein (anti-repression trans-activator protein) Peptidase_S46 PF10459.4 EPY52450.1 - 0.27 9.5 10.7 0.3 9.4 7.4 1.1 1 0 0 1 1 1 0 Peptidase S46 SKI PF01202.17 EPY52450.1 - 0.43 10.4 5.8 3.5 7.4 4.0 2.0 1 1 0 1 1 1 0 Shikimate kinase DUF87 PF01935.12 EPY52450.1 - 0.49 10.1 8.6 1.5 8.5 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 YlqD PF11068.3 EPY52450.1 - 3.4 7.6 14.8 13 5.7 3.3 2.6 1 1 1 2 2 2 0 YlqD protein mRNA_triPase PF02940.10 EPY52451.1 - 4.8e-56 189.8 0.4 6.4e-56 189.4 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain dUTPase PF00692.14 EPY52452.1 - 1.9e-41 140.5 0.0 2.2e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 dUTPase Pkinase PF00069.20 EPY52453.1 - 2.6e-68 230.0 0.0 5.3e-68 228.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52453.1 - 3.8e-33 114.6 0.0 1.1e-32 113.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EPY52453.1 - 0.0082 15.8 0.0 0.14 11.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1506 PF07405.6 EPY52453.1 - 0.039 13.9 0.2 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1506) zf-C2H2_jaz PF12171.3 EPY52454.1 - 1.5e-08 34.5 3.7 3.1e-08 33.5 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPY52454.1 - 0.012 15.8 2.9 0.021 15.0 2.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ribosomal_S26e PF01283.14 EPY52454.1 - 0.076 13.2 0.2 0.076 13.2 0.2 1.7 2 0 0 2 2 2 0 Ribosomal protein S26e zf-C2H2_2 PF12756.2 EPY52454.1 - 0.37 10.9 3.8 0.52 10.4 2.6 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) JAB PF01398.16 EPY52455.1 - 1e-18 67.1 0.1 5.9e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EPY52455.1 - 1.3e-07 31.1 0.0 2.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EPY52455.1 - 0.00061 19.7 1.1 0.0012 18.7 0.8 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain SRP14 PF02290.10 EPY52456.1 - 1.1e-17 63.6 1.8 2.5e-17 62.5 0.0 2.2 1 1 1 2 2 2 1 Signal recognition particle 14kD protein Sial-lect-inser PF09264.5 EPY52456.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion Peptidase_C54 PF03416.14 EPY52457.1 - 1.2e-73 247.6 0.0 3.2e-73 246.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EPY52457.1 - 0.048 12.7 0.1 0.33 10.0 0.0 2.2 2 1 1 3 3 3 0 Peptidase family C78 zf-C2H2_2 PF12756.2 EPY52458.1 - 8.3e-18 64.3 12.1 3.9e-16 58.9 3.2 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EPY52458.1 - 0.029 14.2 1.7 0.029 14.2 1.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EPY52458.1 - 1.4 9.1 15.8 6.7 6.9 0.1 4.2 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 EPY52458.1 - 4 7.2 10.0 1.6 8.5 0.1 3.9 4 0 0 4 4 4 0 BED zinc finger Rhomboid PF01694.17 EPY52459.1 - 1.8e-08 34.5 14.0 1.8e-08 34.5 9.7 1.8 1 1 1 2 2 2 1 Rhomboid family NIF PF03031.13 EPY52460.1 - 2.8e-27 95.3 0.2 8.2e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EPY52460.1 - 2.7e-08 33.5 0.0 7.2e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPY52460.1 - 0.002 18.2 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_S30 PF04758.9 EPY52461.1 - 8.7e-28 95.8 5.4 1e-27 95.6 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 Glucan_synthase PF02364.10 EPY52462.1 - 0 1296.1 0.1 0 1295.5 0.1 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPY52462.1 - 8.3e-38 128.8 1.3 1.9e-37 127.7 0.9 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 EPY52463.1 - 3.3e-129 430.3 9.5 4.7e-129 429.8 6.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPY52463.1 - 2.4e-19 69.5 6.1 2.4e-19 69.5 4.2 2.3 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.13 EPY52463.1 - 0.00014 21.1 1.4 0.00084 18.6 1.0 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1903 PF08991.5 EPY52464.1 - 2.4e-18 66.0 10.4 2.5e-18 65.9 7.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EPY52464.1 - 0.027 14.3 11.7 0.055 13.4 8.1 1.5 1 0 0 1 1 1 0 CHCH domain Xpo1 PF08389.7 EPY52464.1 - 0.034 14.0 0.3 0.035 14.0 0.2 1.2 1 0 0 1 1 1 0 Exportin 1-like protein Cmc1 PF08583.5 EPY52464.1 - 0.34 10.7 12.0 0.38 10.5 0.9 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Atracotoxin PF05353.6 EPY52464.1 - 5.5 6.9 13.9 2.6 7.9 1.5 2.3 1 1 1 2 2 2 0 Delta Atracotoxin BCMA-Tall_bind PF09257.5 EPY52464.1 - 7.6 6.5 10.2 0.27 11.2 2.6 1.9 2 1 0 2 2 2 0 BCMA, TALL-1 binding TPR_11 PF13414.1 EPY52465.1 - 2e-15 56.1 0.8 2.8e-07 30.0 0.0 4.9 2 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 EPY52465.1 - 3.8e-11 42.5 0.0 0.099 13.3 0.0 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPY52465.1 - 4.2e-10 38.7 0.2 0.00041 19.8 0.0 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52465.1 - 6.9e-10 38.0 0.1 0.00066 19.4 0.0 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52465.1 - 1.7e-08 33.9 0.9 0.0059 16.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52465.1 - 6e-07 29.6 0.0 0.055 13.8 0.0 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52465.1 - 9.3e-06 26.1 1.3 0.21 12.3 0.0 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPY52465.1 - 1.3e-05 24.6 0.0 0.096 12.5 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPY52465.1 - 0.00039 20.2 0.0 0.81 9.5 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52465.1 - 0.0011 18.8 4.7 2.3 8.2 0.0 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EPY52465.1 - 0.012 15.7 0.0 1.4 9.0 0.0 3.2 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPY52465.1 - 0.041 14.3 0.2 70 4.2 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Glutaredoxin PF00462.19 EPY52466.1 - 6.7e-17 61.2 0.2 8.5e-17 60.9 0.2 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EPY52466.1 - 0.001 19.2 0.5 0.0021 18.2 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EPY52466.1 - 0.0029 17.1 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EPY52466.1 - 0.0038 17.2 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EPY52466.1 - 0.0079 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Zn_ribbon_2 PF12674.2 EPY52466.1 - 0.042 14.1 0.0 0.054 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF3083 PF11281.3 EPY52466.1 - 0.067 12.3 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) Thioredoxin_4 PF13462.1 EPY52466.1 - 0.068 13.1 2.0 1.5 8.7 0.7 2.0 1 1 1 2 2 2 0 Thioredoxin DUF836 PF05768.9 EPY52466.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) zf-HIT PF04438.11 EPY52467.1 - 4.7e-11 42.1 10.8 7.8e-11 41.4 7.5 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.6 EPY52467.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-C2H2_4 PF13894.1 EPY52467.1 - 0.14 12.5 6.8 0.3 11.5 4.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-MYND PF01753.13 EPY52467.1 - 0.41 10.5 14.3 0.76 9.7 9.9 1.4 1 0 0 1 1 1 0 MYND finger zf-Mss51 PF13824.1 EPY52467.1 - 1.3 8.9 10.0 3.6 7.5 7.0 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2 PF00096.21 EPY52467.1 - 3.1 8.3 5.1 6.2 7.3 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type WD40 PF00400.27 EPY52468.1 - 2.6e-09 36.6 0.4 0.001 18.8 0.1 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3315 PF11776.3 EPY52468.1 - 0.046 13.2 0.1 0.23 11.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3315) Blt1 PF12754.2 EPY52469.1 - 0.045 13.3 3.3 0.053 13.1 2.3 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component DUF883 PF05957.8 EPY52469.1 - 0.07 13.5 8.3 0.86 10.0 0.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF445 PF04286.7 EPY52469.1 - 0.072 12.6 5.9 0.081 12.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ApoLp-III PF07464.6 EPY52469.1 - 0.077 13.0 14.9 0.1 12.6 10.3 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Mis14 PF08641.7 EPY52469.1 - 0.13 12.2 7.4 0.16 12.0 4.7 1.4 1 1 0 1 1 1 0 Kinetochore protein Mis14 like DUF763 PF05559.6 EPY52469.1 - 0.19 10.6 2.4 0.22 10.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) AAA_13 PF13166.1 EPY52469.1 - 0.22 9.9 11.4 0.24 9.8 7.9 1.0 1 0 0 1 1 1 0 AAA domain DUF651 PF04895.7 EPY52469.1 - 0.29 10.7 3.7 0.36 10.4 0.3 2.0 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF651) Exonuc_VII_L PF02601.10 EPY52469.1 - 0.42 9.7 10.4 0.46 9.6 7.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.3 EPY52469.1 - 0.45 9.1 2.4 0.5 8.9 1.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GlutR_dimer PF00745.15 EPY52469.1 - 0.69 9.8 10.2 0.17 11.8 3.1 2.0 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Neur_chan_memb PF02932.11 EPY52469.1 - 1.8 8.4 4.1 1.9 8.3 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF29 PF01724.11 EPY52469.1 - 1.9 8.2 6.4 1.6 8.5 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF29 Atg14 PF10186.4 EPY52469.1 - 3.5 6.5 9.7 4.2 6.2 6.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PRTP PF01366.13 EPY52469.1 - 4.1 5.2 9.1 4.4 5.1 6.3 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ATP-synt_B PF00430.13 EPY52469.1 - 8.5 6.1 15.6 23 4.7 10.1 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Spore_II_R PF09551.5 EPY52469.1 - 9.8 6.2 8.1 9.8 6.2 2.7 2.0 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) E1-E2_ATPase PF00122.15 EPY52470.1 - 4e-14 52.2 0.0 1.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EPY52470.1 - 3.5e-13 50.1 0.0 1e-12 48.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY52470.1 - 1.2e-11 44.4 0.0 3.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EPY52470.1 - 4e-11 43.7 0.0 2.4e-09 37.9 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPY52470.1 - 0.00099 18.7 0.1 0.0029 17.2 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase WH1 PF00568.18 EPY52471.1 - 2.3e-22 78.8 0.0 3.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain NAC PF01849.13 EPY52472.1 - 5.6e-20 70.6 0.3 5.6e-20 70.6 0.2 1.5 2 0 0 2 2 2 1 NAC domain DUF236 PF03057.9 EPY52472.1 - 0.0054 16.6 1.8 0.015 15.2 1.2 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF999 PF06198.6 EPY52473.1 - 2.7e-08 33.7 2.8 1.6e-07 31.2 2.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF999) DUF575 PF04746.7 EPY52473.1 - 0.34 10.9 3.3 0.58 10.2 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF575) CENP-P PF13096.1 EPY52474.1 - 0.079 12.2 0.1 0.086 12.1 0.1 1.0 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P GYF PF02213.11 EPY52475.1 - 2.7e-18 65.2 0.6 8.7e-18 63.6 0.2 2.1 2 0 0 2 2 2 1 GYF domain CENP-L PF13092.1 EPY52476.1 - 1.5e-20 73.5 4.1 2e-20 73.1 2.2 1.7 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 Septin PF00735.13 EPY52477.1 - 2.4e-103 345.0 0.0 2.4e-103 345.0 0.0 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EPY52477.1 - 3.7e-07 30.1 0.0 9.5e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPY52477.1 - 5.4e-07 29.2 0.8 0.00092 18.6 0.0 2.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPY52477.1 - 2.3e-05 23.6 0.2 6e-05 22.2 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPY52477.1 - 8.7e-05 22.4 5.0 0.00046 20.0 0.0 3.0 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.11 EPY52477.1 - 0.00022 20.3 0.0 0.00022 20.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 EPY52477.1 - 0.00028 20.4 0.5 0.00087 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EPY52477.1 - 0.00063 19.7 0.0 0.0026 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EPY52477.1 - 0.00072 19.0 0.8 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_tran PF00005.22 EPY52477.1 - 0.0029 17.9 3.6 0.0071 16.6 0.0 2.8 2 1 0 2 2 2 1 ABC transporter PduV-EutP PF10662.4 EPY52477.1 - 0.003 17.0 0.2 0.61 9.5 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EPY52477.1 - 0.0038 16.7 0.0 0.0076 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EPY52477.1 - 0.0056 16.8 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EPY52477.1 - 0.0093 16.4 0.3 0.046 14.2 0.0 2.3 3 0 0 3 3 2 1 Miro-like protein cobW PF02492.14 EPY52477.1 - 0.012 15.0 0.1 0.087 12.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EPY52477.1 - 0.02 13.7 0.9 0.11 11.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_32 PF13654.1 EPY52477.1 - 0.032 12.8 6.9 0.31 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EPY52477.1 - 0.049 13.4 0.0 0.049 13.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EPY52477.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPY52477.1 - 0.094 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EPY52477.1 - 0.19 10.8 0.1 0.19 10.8 0.1 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Exonuc_VII_L PF02601.10 EPY52477.1 - 0.35 10.0 7.2 0.52 9.4 5.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_18 PF13238.1 EPY52477.1 - 1.8 8.9 6.3 2.7 8.3 0.0 3.1 2 1 1 3 3 3 0 AAA domain Anp1 PF03452.9 EPY52478.1 - 4.7e-101 337.4 0.0 5.8e-101 337.1 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EPY52478.1 - 0.0013 18.4 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 CBF PF03914.12 EPY52479.1 - 1.3e-41 141.7 1.2 3.2e-41 140.5 0.1 2.4 2 0 0 2 2 2 1 CBF/Mak21 family ATG13 PF10033.4 EPY52480.1 - 2.5e-60 203.7 0.4 7.3e-60 202.2 0.1 1.9 2 0 0 2 2 2 1 Autophagy-related protein 13 BUD22 PF09073.5 EPY52481.1 - 2.2e-55 188.4 29.1 3.7e-55 187.7 20.2 1.4 1 0 0 1 1 1 1 BUD22 BPL_LplA_LipB PF03099.14 EPY52482.1 - 1e-15 57.8 0.0 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PTPA PF03095.10 EPY52483.1 - 4.7e-109 364.1 0.0 5.3e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FtsJ PF01728.14 EPY52484.1 - 4.4e-66 222.3 0.0 5.3e-66 222.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EPY52484.1 - 0.0091 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY52484.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MLANA PF14991.1 EPY52485.1 - 0.072 13.1 1.7 2.6 8.0 0.1 2.2 1 1 1 2 2 2 0 Protein melan-A Actin PF00022.14 EPY52486.1 - 5.2e-88 295.1 0.0 1.9e-87 293.2 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPY52486.1 - 0.00031 19.4 0.0 0.18 10.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EPY52486.1 - 0.062 13.1 0.0 1.3 8.8 0.0 2.4 2 1 0 2 2 2 0 Cell division protein FtsA DUF2361 PF10153.4 EPY52488.1 - 1.4e-33 115.4 17.1 1.4e-33 115.4 11.9 1.8 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) RRM_6 PF14259.1 EPY52489.1 - 1.8e-07 30.9 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY52489.1 - 5e-07 29.2 0.1 9.3e-07 28.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52489.1 - 7.1e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 EPY52490.1 - 7.4e-115 384.3 5.6 8.4e-115 384.1 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIID-31kDa PF02291.10 EPY52491.1 - 8e-55 184.1 0.0 1.3e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EPY52491.1 - 0.036 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RTC PF01137.16 EPY52492.1 - 3.7e-65 218.9 0.0 4.6e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EPY52492.1 - 1.3e-32 111.8 0.0 2.1e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ribosomal_L6 PF00347.18 EPY52494.1 - 2e-27 95.4 0.3 2e-12 47.4 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2665 PF11654.3 EPY52495.1 - 2.5e-19 68.5 0.4 2.8e-19 68.4 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF4221 PF13970.1 EPY52497.1 - 0.091 12.0 0.3 0.091 12.0 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4221) WD40 PF00400.27 EPY52497.1 - 0.57 10.1 6.2 24 5.0 0.1 4.6 5 1 0 5 5 5 0 WD domain, G-beta repeat DUF544 PF04424.8 EPY52498.1 - 1.5e-18 66.7 0.0 2.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) RIC3 PF15361.1 EPY52498.1 - 0.09 13.0 0.9 0.14 12.4 0.6 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SET PF00856.23 EPY52499.1 - 0.0046 17.2 0.2 0.013 15.8 0.1 2.0 1 1 1 2 2 2 1 SET domain DUF1027 PF06265.6 EPY52499.1 - 0.03 14.1 0.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) DUF1162 PF06650.7 EPY52500.1 - 3.3e-61 206.9 8.4 5.4e-60 202.9 0.7 4.1 4 1 0 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EPY52500.1 - 6.5e-37 125.6 0.2 1.8e-36 124.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EPY52500.1 - 0.00053 20.1 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain NUFIP1 PF10453.4 EPY52501.1 - 2e-13 49.6 9.4 2e-13 49.6 6.5 2.3 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) SUI1 PF01253.17 EPY52504.1 - 1.5e-19 69.5 0.8 3.2e-19 68.5 0.6 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Packaging_FI PF14000.1 EPY52504.1 - 0.019 15.1 1.3 0.028 14.6 0.9 1.2 1 0 0 1 1 1 0 DNA packaging protein FI BNR_2 PF13088.1 EPY52505.1 - 2.8e-09 36.6 1.5 0.055 12.7 0.0 6.2 5 1 1 6 6 6 4 BNR repeat-like domain BNR PF02012.15 EPY52505.1 - 6.9e-09 34.2 51.5 0.74 9.8 0.1 12.7 13 0 0 13 13 13 9 BNR/Asp-box repeat PSII_BNR PF14870.1 EPY52505.1 - 0.0058 15.6 2.3 2.3 7.1 0.0 4.5 5 1 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 AAA PF00004.24 EPY52506.1 - 2.2e-40 137.9 0.0 3.7e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY52506.1 - 3.2e-06 27.3 0.0 0.0005 20.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPY52506.1 - 1.8e-05 24.5 0.0 7.2e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPY52506.1 - 0.00016 21.6 0.0 0.0006 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPY52506.1 - 0.00034 20.6 0.0 0.0015 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EPY52506.1 - 0.00082 19.0 0.1 0.0097 15.6 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 EPY52506.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPY52506.1 - 0.0031 18.3 0.1 0.0076 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPY52506.1 - 0.0036 16.3 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPY52506.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPY52506.1 - 0.0088 16.0 0.2 0.018 14.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EPY52506.1 - 0.011 15.5 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPY52506.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EPY52506.1 - 0.026 14.5 0.0 0.064 13.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EPY52506.1 - 0.027 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EPY52506.1 - 0.04 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EPY52506.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPY52506.1 - 0.054 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EPY52506.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EPY52506.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPY52506.1 - 0.11 11.9 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EPY52506.1 - 0.12 12.0 0.0 8 6.0 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase UCR_hinge PF02320.11 EPY52507.1 - 1.1e-19 70.0 9.8 2.4e-19 68.9 6.8 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein SprA-related PF12118.3 EPY52507.1 - 0.026 13.8 30.0 0.035 13.4 20.8 1.1 1 0 0 1 1 1 0 SprA-related family UPF0203 PF05254.7 EPY52507.1 - 0.069 13.0 6.1 0.15 11.8 4.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) FAM150 PF15129.1 EPY52507.1 - 0.25 11.2 8.8 0.045 13.6 2.2 2.6 1 1 2 3 3 3 0 FAM150 family Mitofilin PF09731.4 EPY52507.1 - 6.7 5.2 24.6 9.6 4.7 17.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAT1 PF09770.4 EPY52507.1 - 8.9 4.4 25.2 10 4.1 17.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PMT PF02366.13 EPY52508.1 - 1.6e-79 266.7 18.7 1.6e-79 266.7 12.9 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPY52508.1 - 5e-14 52.2 0.2 2.8e-13 49.8 0.1 2.0 1 1 1 2 2 2 2 MIR domain Chromo PF00385.19 EPY52509.1 - 4e-13 48.8 2.1 4e-13 48.8 1.4 2.8 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EPY52509.1 - 9.9e-11 41.3 0.7 4.5e-10 39.2 0.0 2.4 3 0 0 3 3 3 1 Chromo shadow domain Imm23 PF15593.1 EPY52509.1 - 0.12 12.5 1.4 0.39 10.9 0.1 2.1 1 1 1 2 2 2 0 Immunity protein 23 Ribosomal_L32e PF01655.13 EPY52510.1 - 3.1e-48 162.3 1.4 3.7e-48 162.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Las1 PF04031.8 EPY52511.1 - 7.4e-41 139.3 0.1 5.4e-40 136.5 0.0 2.3 2 0 0 2 2 2 1 Las1-like Laminin_II PF06009.7 EPY52511.1 - 0.11 12.2 1.1 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Laminin Domain II ACBP PF00887.14 EPY52511.1 - 0.11 12.1 1.3 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 Acyl CoA binding protein Coatomer_WDAD PF04053.9 EPY52512.1 - 2.2e-148 494.7 0.9 5.9e-148 493.3 0.1 2.0 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EPY52512.1 - 3.9e-49 162.8 7.7 1.5e-10 40.4 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPY52512.1 - 0.0097 14.2 0.2 0.22 9.8 0.1 2.7 2 1 0 2 2 2 1 Cytochrome D1 heme domain U3_assoc_6 PF08640.6 EPY52513.1 - 8.1e-28 96.0 4.2 2.1e-27 94.7 2.9 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 DUF4359 PF14271.1 EPY52513.1 - 0.4 11.0 3.2 3.6 7.9 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4359) NRDE-2 PF08424.5 EPY52513.1 - 0.68 8.7 3.6 1.1 8.0 0.1 2.5 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference His_Phos_2 PF00328.17 EPY52514.1 - 6.2e-47 160.5 0.0 7.6e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SID PF11778.3 EPY52515.1 - 1.4e-19 70.3 0.4 3.6e-19 69.0 0.1 1.8 2 0 0 2 2 2 1 Septation initiation Phage_GP20 PF06810.6 EPY52515.1 - 0.11 11.9 7.4 0.2 11.0 0.1 3.2 3 0 0 3 3 3 0 Phage minor structural protein GP20 Ribonucleas_3_3 PF14622.1 EPY52516.1 - 6.3e-21 74.6 0.0 8.2e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Lyase_1 PF00206.15 EPY52517.1 - 3.9e-100 335.0 0.0 6.3e-100 334.3 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EPY52517.1 - 5.3e-26 90.4 0.0 1.1e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal TSLP PF15216.1 EPY52517.1 - 0.052 13.2 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 Thymic stromal lymphopoietin RED_N PF07808.8 EPY52518.1 - 3.5e-07 29.7 0.2 3.5e-07 29.7 0.2 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region Clr2 PF10383.4 EPY52518.1 - 0.12 12.3 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 UPF0121 PF03661.8 EPY52519.1 - 2.6e-14 53.0 11.4 3.2e-14 52.7 7.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Adenyl_transf PF04439.7 EPY52519.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Sec34 PF04136.10 EPY52520.1 - 2.3e-41 141.1 5.2 5.4e-41 139.9 2.6 2.5 2 0 0 2 2 2 1 Sec34-like family TPR_MLP1_2 PF07926.7 EPY52520.1 - 0.009 15.7 1.1 0.028 14.1 0.8 1.8 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Snf7 PF03357.16 EPY52520.1 - 0.025 13.9 1.6 0.054 12.8 0.3 2.1 2 0 0 2 2 2 0 Snf7 FliJ PF02050.11 EPY52520.1 - 0.16 12.0 4.2 0.27 11.3 0.5 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein ACBP PF00887.14 EPY52521.1 - 1.1e-30 105.0 1.6 1.2e-30 104.9 1.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein ADH_zinc_N PF00107.21 EPY52522.1 - 3.7e-27 94.4 1.3 2.6e-26 91.6 0.9 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPY52522.1 - 2.3e-26 91.6 0.4 2.3e-26 91.6 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPY52522.1 - 0.011 16.6 0.0 0.025 15.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPY52522.1 - 0.017 14.2 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPY52522.1 - 0.049 13.0 0.3 0.081 12.2 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EPY52522.1 - 0.075 13.4 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1304 PF06993.7 EPY52522.1 - 0.15 11.8 0.8 0.28 10.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) AlaDh_PNT_C PF01262.16 EPY52522.1 - 0.16 11.4 2.8 0.17 11.4 1.0 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EPY52522.1 - 0.56 10.0 5.4 3.3 7.5 2.2 2.3 1 1 1 2 2 2 0 ThiF family Arf PF00025.16 EPY52523.1 - 2.5e-72 241.7 0.1 2.9e-72 241.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPY52523.1 - 4.1e-12 45.6 0.0 5e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EPY52523.1 - 4.3e-12 45.4 0.9 3.2e-08 32.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EPY52523.1 - 1.8e-11 43.6 0.0 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EPY52523.1 - 2.3e-09 36.7 0.0 2.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPY52523.1 - 3.4e-06 27.5 0.0 5.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPY52523.1 - 0.00047 20.0 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EPY52523.1 - 0.0011 18.1 0.4 0.011 14.7 0.1 1.9 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EPY52523.1 - 0.024 14.0 0.0 0.18 11.2 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain IGPS PF00218.16 EPY52524.1 - 2.7e-94 314.9 0.5 5.6e-94 313.9 0.2 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EPY52524.1 - 4.3e-52 176.5 0.0 6.5e-48 162.9 0.0 2.4 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EPY52524.1 - 4.5e-50 169.7 0.0 9.2e-50 168.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPY52524.1 - 2.4e-09 36.9 0.1 4e-08 32.9 0.1 2.7 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 EPY52524.1 - 0.085 12.3 4.7 0.26 10.8 0.1 3.2 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain GATase_3 PF07685.9 EPY52524.1 - 0.11 12.1 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Fig1 PF12351.3 EPY52526.1 - 0.0068 16.3 0.4 0.0098 15.7 0.3 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 Antimicrobial10 PF08105.6 EPY52526.1 - 0.14 11.7 0.1 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Metchnikowin family Alpha-amylase PF00128.19 EPY52528.1 - 9.7e-94 314.2 2.0 1.7e-93 313.4 1.4 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EPY52528.1 - 0.00034 20.6 0.1 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain GPI-anchored PF10342.4 EPY52529.1 - 6e-10 39.4 0.1 7.4e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family B1 PF02246.10 EPY52529.1 - 0.13 12.0 0.0 0.94 9.3 0.0 2.1 1 1 0 1 1 1 0 Protein L b1 domain NmrA PF05368.8 EPY52531.1 - 2.1e-54 184.2 0.8 2.6e-54 183.9 0.6 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPY52531.1 - 6.6e-10 39.2 0.0 8.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPY52531.1 - 4.7e-06 25.5 0.3 7.2e-06 24.8 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EPY52531.1 - 0.016 15.2 0.2 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EPY52531.1 - 0.035 13.0 0.1 0.052 12.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 EPY52531.1 - 0.065 12.6 0.2 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3897 PF13036.1 EPY52531.1 - 0.18 11.3 0.9 2.5 7.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3897) WW PF00397.21 EPY52533.1 - 0.023 14.5 0.3 0.023 14.5 0.2 2.0 2 0 0 2 2 2 0 WW domain DUF2076 PF09849.4 EPY52533.1 - 0.83 9.6 5.6 1.1 9.2 3.7 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3808 PF10300.4 EPY52535.1 - 6.9e-110 367.7 5.0 8.5e-110 367.4 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.1 EPY52535.1 - 0.045 13.5 3.2 13 5.8 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YgbB PF02542.11 EPY52535.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 YgbB family TPR_12 PF13424.1 EPY52535.1 - 0.27 11.1 4.7 5.1 7.1 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_L22e PF01776.12 EPY52536.1 - 2.3e-46 156.4 1.6 2.7e-46 156.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family 2OG-FeII_Oxy_2 PF13532.1 EPY52537.1 - 4.3e-13 49.5 0.0 8.2e-13 48.6 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPY52537.1 - 0.00033 20.8 0.0 0.00066 19.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-L PF02585.12 EPY52538.1 - 2.1e-23 83.2 0.0 3.1e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase TRAPP PF04051.11 EPY52539.1 - 2e-39 134.5 0.0 2.5e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SSB PF00436.20 EPY52539.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Dsl1_N PF11988.3 EPY52539.1 - 0.035 12.9 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal RRM_1 PF00076.17 EPY52540.1 - 4.5e-18 64.6 0.0 7.4e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 EPY52540.1 - 2.8e-16 59.3 0.9 4e-16 58.8 0.1 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_6 PF14259.1 EPY52540.1 - 8.3e-11 41.7 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EPY52540.1 - 2.6e-09 36.2 3.1 5.1e-09 35.2 2.2 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EPY52540.1 - 0.0083 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L3 PF00297.17 EPY52541.1 - 9.5e-35 120.2 0.1 6.3e-34 117.5 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 LexA_DNA_bind PF01726.11 EPY52541.1 - 0.058 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Ribosomal_60s PF00428.14 EPY52542.1 - 3.9e-25 88.0 9.2 4.8e-25 87.7 6.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rad51 PF08423.6 EPY52543.1 - 1.6e-125 417.1 0.0 2.2e-125 416.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPY52543.1 - 1.2e-08 34.6 0.1 2.7e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EPY52543.1 - 1.4e-08 34.7 0.1 5.9e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain KaiC PF06745.8 EPY52543.1 - 0.0021 17.1 0.1 0.0057 15.7 0.1 1.7 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EPY52543.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Yip1 PF04893.12 EPY52544.1 - 3e-10 39.8 12.9 4e-10 39.4 9.0 1.2 1 0 0 1 1 1 1 Yip1 domain Myb_Cef PF11831.3 EPY52545.1 - 2.6e-37 128.2 8.5 2.6e-37 128.2 5.9 4.0 4 2 1 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EPY52545.1 - 5.4e-23 80.7 5.6 7e-12 45.2 0.4 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY52545.1 - 5.8e-19 67.9 9.2 2.2e-13 50.0 2.7 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain E1_DerP2_DerF2 PF02221.10 EPY52546.1 - 4.3e-20 72.3 0.1 5.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EPY52546.1 - 0.0042 17.1 0.2 0.022 14.7 0.1 1.9 1 1 0 1 1 1 1 ML-like domain SLAC1 PF03595.12 EPY52547.1 - 5e-71 239.0 53.2 5.6e-71 238.8 36.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 EPY52548.1 - 5e-71 239.0 53.2 5.6e-71 238.8 36.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel BCS1_N PF08740.6 EPY52549.1 - 4.2e-49 166.7 0.0 5.6e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EPY52549.1 - 8.2e-20 71.3 0.0 1.5e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPY52549.1 - 4.3e-05 24.3 0.0 9.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPY52549.1 - 0.001 18.7 0.1 0.062 12.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EPY52549.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPY52549.1 - 0.0034 17.6 0.0 0.009 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPY52549.1 - 0.0043 17.0 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY52549.1 - 0.023 14.6 0.0 0.081 12.8 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EPY52549.1 - 0.024 14.7 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY52549.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPY52549.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EPY52549.1 - 0.053 13.2 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EPY52549.1 - 0.057 12.4 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EPY52549.1 - 0.074 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EPY52549.1 - 0.077 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EPY52549.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPY52549.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EPY52549.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EPY52549.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 EPY52549.1 - 0.19 10.5 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EPY52549.1 - 0.19 11.4 0.3 0.82 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) HAD_2 PF13419.1 EPY52550.1 - 6.1e-25 88.4 0.0 7.4e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ala_racemase_N PF01168.15 EPY52551.1 - 5.2e-39 134.0 0.0 5.8e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Phage_GPA PF05840.8 EPY52551.1 - 0.062 11.9 0.1 0.09 11.4 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Ala_racemase_N PF01168.15 EPY52552.1 - 4.3e-44 150.6 0.0 5.2e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Phage_GPA PF05840.8 EPY52552.1 - 0.078 11.6 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) BCDHK_Adom3 PF10436.4 EPY52553.1 - 2.4e-28 98.7 0.0 3.3e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPY52553.1 - 2.7e-16 59.2 0.0 4.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPY52553.1 - 5.1e-06 26.1 0.0 2.2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med11 PF10280.4 EPY52554.1 - 2.4e-10 40.4 0.3 3.2e-10 40.0 0.2 1.2 1 0 0 1 1 1 1 Mediator complex protein DUF371 PF04027.8 EPY52554.1 - 0.036 13.7 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF371) TPP1 PF10341.4 EPY52554.1 - 0.12 12.3 0.1 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD M-factor PF03855.8 EPY52555.1 - 0.00014 21.7 5.5 0.00033 20.5 3.8 1.7 1 0 0 1 1 1 1 M-factor Herpes_UL25 PF01499.11 EPY52555.1 - 0.07 11.4 0.1 0.1 10.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Ribosomal_L3 PF00297.17 EPY52556.1 - 2.1e-120 401.0 6.7 2.5e-120 400.7 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 NUC173 PF08161.7 EPY52557.1 - 2.3e-66 222.9 1.2 2.2e-61 206.6 0.0 3.9 4 0 0 4 4 4 2 NUC173 domain HEAT PF02985.17 EPY52557.1 - 0.00049 19.9 2.0 0.19 11.9 0.1 5.0 4 0 0 4 4 4 1 HEAT repeat Ipi1_N PF12333.3 EPY52557.1 - 0.00069 19.5 10.4 0.019 14.8 0.0 4.6 4 1 1 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation TFCD_C PF12612.3 EPY52557.1 - 0.2 11.0 10.2 1.7 8.0 0.4 4.4 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal Mak16 PF04874.9 EPY52557.1 - 2.8 8.0 15.8 0.32 11.1 7.0 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region TIP49 PF06068.8 EPY52558.1 - 1.4e-190 633.2 0.5 1.6e-190 633.0 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPY52558.1 - 2.3e-09 37.5 0.4 5e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPY52558.1 - 2.1e-08 33.5 1.1 0.00037 19.6 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPY52558.1 - 0.00081 19.5 0.5 0.51 10.4 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EPY52558.1 - 0.001 19.1 0.0 0.2 11.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EPY52558.1 - 0.016 14.1 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EPY52558.1 - 0.017 15.1 0.1 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPY52558.1 - 0.018 14.7 0.1 0.055 13.2 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EPY52558.1 - 0.036 13.2 0.1 5.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPY52558.1 - 0.057 13.1 0.2 12 5.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) B12D PF06522.6 EPY52559.1 - 0.00035 20.1 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit UPRTase PF14681.1 EPY52560.1 - 2.2e-69 232.7 0.0 4.6e-68 228.4 0.0 2.0 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPY52560.1 - 5e-05 23.0 0.0 8.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.8 EPY52561.1 - 6.8e-15 54.5 6.0 2.5e-14 52.7 4.1 1.8 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like SCA7 PF08313.7 EPY52561.1 - 0.028 14.0 0.5 0.038 13.5 0.3 1.2 1 0 0 1 1 1 0 SCA7, zinc-binding domain Pro_isomerase PF00160.16 EPY52562.1 - 3.3e-44 150.8 0.5 5.5e-44 150.0 0.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EPY52562.1 - 8.7e-08 31.7 5.6 5.5e-07 29.1 0.5 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EPY52562.1 - 1.5e-06 27.6 11.2 0.023 14.5 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPY52562.1 - 2.3e-06 26.9 11.3 0.0099 15.4 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52562.1 - 0.00063 20.3 3.7 0.012 16.2 0.1 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52562.1 - 0.0017 18.2 5.4 1 9.3 1.8 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPY52562.1 - 0.013 15.2 6.3 8.1 6.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52562.1 - 0.11 12.7 5.2 5.6 7.4 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Spc24 PF08286.6 EPY52562.1 - 0.38 10.4 2.8 0.22 11.2 0.3 1.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_6 PF13174.1 EPY52562.1 - 0.51 10.9 5.9 31 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPY52562.1 - 7.8 6.5 12.2 0.67 9.8 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 EPY52563.1 - 3.9e-47 160.1 0.0 5.7e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EPY52563.1 - 1.1e-38 131.4 0.4 2.8e-38 130.1 0.3 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EPY52563.1 - 4.5e-20 71.3 0.0 1.4e-19 69.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPY52563.1 - 2.2e-09 37.2 0.3 4e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPY52563.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EPY52563.1 - 0.0014 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EPY52563.1 - 0.0024 17.1 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EPY52563.1 - 0.07 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Not3 PF04065.10 EPY52564.1 - 3.6e-92 307.8 23.7 4.9e-92 307.4 16.4 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EPY52564.1 - 1.3e-43 148.1 5.8 1.3e-43 148.1 4.0 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EPY52564.1 - 0.0063 16.0 1.1 0.02 14.4 0.7 1.9 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EPY52564.1 - 0.023 14.6 0.3 0.023 14.6 0.2 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 P3A PF08727.6 EPY52564.1 - 0.12 11.7 1.4 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Poliovirus 3A protein like Syntaxin_2 PF14523.1 EPY52564.1 - 0.21 11.6 8.8 0.37 10.8 1.7 2.8 2 1 0 2 2 2 0 Syntaxin-like protein DUF948 PF06103.6 EPY52564.1 - 1.2 9.0 3.8 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.1 EPY52564.1 - 4.7 7.5 9.8 1 9.7 0.7 2.4 2 0 0 2 2 2 0 Snapin/Pallidin VPS28 PF03997.7 EPY52565.1 - 5.2e-63 212.0 0.8 9.2e-63 211.2 0.6 1.4 1 1 0 1 1 1 1 VPS28 protein PDDEXK_2 PF12784.2 EPY52565.1 - 0.034 13.3 0.3 0.062 12.4 0.2 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase Coiled-coil_56 PF09813.4 EPY52567.1 - 2e-07 30.9 0.1 2.6e-07 30.5 0.1 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF533 PF04391.7 EPY52567.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) PCI PF01399.22 EPY52568.1 - 2e-12 47.3 0.0 4.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain Noc2 PF03715.8 EPY52569.1 - 7.5e-63 212.1 11.9 1.4e-62 211.2 8.2 1.4 1 0 0 1 1 1 1 Noc2p family BP28CT PF08146.7 EPY52569.1 - 0.00053 19.7 0.5 0.0015 18.2 0.3 1.8 1 0 0 1 1 1 1 BP28CT (NUC211) domain Sel1 PF08238.7 EPY52570.1 - 5.4e-20 71.3 33.3 5.1e-07 30.1 1.4 10.1 11 0 0 11 11 11 6 Sel1 repeat TPR_11 PF13414.1 EPY52570.1 - 0.00079 19.0 4.3 0.044 13.4 0.6 3.3 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 EPY52570.1 - 0.52 10.2 8.7 13 5.8 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.17 EPY52572.1 - 4.7e-49 165.8 0.0 6.2e-49 165.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY52572.1 - 2.1e-15 57.2 0.0 3.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY52572.1 - 1.8e-11 43.5 0.0 2.4e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY52572.1 - 8.6e-05 21.7 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPY52572.1 - 0.00018 21.0 0.0 0.0011 18.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY52572.1 - 0.00023 21.1 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EPY52572.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EPY52572.1 - 0.0037 16.4 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EPY52572.1 - 0.0055 16.8 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EPY52572.1 - 0.017 14.7 0.1 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 EPY52572.1 - 0.036 14.0 0.0 0.07 13.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPY52572.1 - 0.037 13.2 0.0 0.059 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPY52572.1 - 0.063 13.2 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EPY52572.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EPY52572.1 - 0.11 12.8 0.1 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EPY52572.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_N PF01194.12 EPY52573.1 - 1.7e-31 108.0 0.5 2e-31 107.8 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 EPY52574.1 - 5.3e-05 22.9 0.1 0.79 9.7 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ATP-synt_C PF00137.16 EPY52575.1 - 1.8e-31 107.8 32.0 1e-18 66.9 8.3 2.0 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 EPY52575.1 - 0.62 9.1 2.5 7.7 5.5 1.7 2.0 1 1 0 1 1 1 0 Abscisic acid G-protein coupled receptor MFS_1 PF07690.11 EPY52576.1 - 2.3e-27 95.6 26.4 3.6e-27 95.0 18.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Clr2 PF10383.4 EPY52577.1 - 3.2e-13 49.8 0.0 7.3e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Ribosomal_S11 PF00411.14 EPY52578.1 - 3.6e-07 30.3 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 BcrAD_BadFG PF01869.15 EPY52578.1 - 0.043 13.1 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family PIG-U PF06728.8 EPY52579.1 - 2.2e-91 306.6 38.1 2.8e-91 306.2 26.4 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U G-patch PF01585.18 EPY52580.1 - 0.026 14.2 0.1 0.083 12.6 0.1 1.9 1 0 0 1 1 1 0 G-patch domain Macoilin PF09726.4 EPY52580.1 - 0.65 8.1 24.4 0.77 7.9 16.9 1.0 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 EPY52580.1 - 1.5 6.8 20.3 1.7 6.5 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EPY52580.1 - 1.6 8.5 17.7 2.1 8.1 12.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 EPY52580.1 - 4.7 5.9 16.3 6.3 5.5 11.3 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein OTU PF02338.14 EPY52581.1 - 5.4e-23 81.8 0.1 5.4e-23 81.8 0.1 2.8 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EPY52581.1 - 2.1e-10 40.3 7.2 1.6e-09 37.5 0.0 3.1 2 1 0 2 2 2 1 Peptidase C65 Otubain OmpH PF03938.9 EPY52581.1 - 4.5 7.1 24.3 4.5 7.1 0.5 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Cob_adeno_trans PF01923.13 EPY52581.1 - 4.8 6.9 7.2 0.46 10.2 0.9 2.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase zf-ISL3 PF14690.1 EPY52582.1 - 0.052 13.5 0.8 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Bromodomain PF00439.20 EPY52583.1 - 3.7e-26 90.8 2.2 4.3e-26 90.6 0.5 2.0 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 EPY52583.1 - 2.2e-10 40.5 0.3 5e-10 39.4 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPY52583.1 - 2.9e-09 36.8 0.4 6.5e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPY52583.1 - 0.00097 19.1 1.2 0.028 14.3 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPY52583.1 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY52583.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein CTNNBL PF08216.6 EPY52584.1 - 3.6e-34 116.5 1.7 1.6e-33 114.5 1.2 2.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Rad1 PF02144.11 EPY52585.1 - 6.7e-65 218.5 1.1 7.9e-65 218.3 0.7 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Pyridox_oxidase PF01243.15 EPY52586.1 - 2.2e-12 46.8 0.0 3.8e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AcetylCoA_hydro PF02550.10 EPY52587.1 - 5.3e-49 166.6 0.0 8.5e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EPY52587.1 - 2.3e-42 144.2 0.0 3.6e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EPY52587.1 - 0.0068 15.6 0.1 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 Coenzyme A transferase DUF4448 PF14610.1 EPY52588.1 - 0.081 12.4 0.4 0.081 12.4 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Amidohydro_1 PF01979.15 EPY52589.1 - 1.5e-57 195.7 0.2 2e-57 195.3 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EPY52589.1 - 8.6e-55 184.0 2.0 2e-54 182.8 1.4 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EPY52589.1 - 6.1e-39 131.9 0.0 1.3e-38 130.8 0.0 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EPY52589.1 - 6.1e-37 125.6 0.1 1.4e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EPY52589.1 - 2.4e-07 30.4 1.1 6e-07 29.1 0.7 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPY52589.1 - 0.0033 16.7 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPY52589.1 - 0.084 12.8 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase PCI PF01399.22 EPY52590.1 - 1.7e-06 28.3 0.7 5.3e-06 26.6 0.2 2.2 2 1 0 2 2 2 1 PCI domain LNS2 PF08235.8 EPY52591.1 - 9.5e-74 246.2 0.0 1.5e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EPY52591.1 - 1.8e-42 143.4 0.0 3.8e-42 142.4 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EPY52591.1 - 0.0012 18.3 0.0 0.0052 16.1 0.0 2.0 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 EPY52591.1 - 0.022 14.6 6.1 0.06 13.2 4.2 1.8 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Hydrolase_6 PF13344.1 EPY52591.1 - 0.022 14.6 0.0 0.059 13.2 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RhoGAP PF00620.22 EPY52593.1 - 1.7e-08 34.1 0.3 4.7e-08 32.7 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EPY52593.1 - 0.047 13.8 0.5 0.047 13.8 0.3 3.7 3 1 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Mei4 PF13971.1 EPY52594.1 - 1.7e-32 112.8 12.5 2.2e-32 112.4 8.7 1.0 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 VitD-bind_III PF09164.5 EPY52594.1 - 0.17 11.4 2.5 0.31 10.6 0.1 2.4 2 0 0 2 2 2 0 Vitamin D binding protein, domain III RabGAP-TBC PF00566.13 EPY52595.1 - 1.6e-35 122.5 16.7 3.5e-32 111.6 2.3 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Fib_alpha PF08702.5 EPY52595.1 - 0.091 12.8 0.3 0.85 9.7 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TACC PF05010.9 EPY52596.1 - 1.3e-20 74.0 41.3 1.3e-19 70.8 28.6 2.0 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Kinetocho_Slk19 PF12709.2 EPY52596.1 - 1.7e-12 47.2 33.2 1.6e-11 44.0 3.4 4.8 3 2 1 4 4 4 3 Central kinetochore-associated DUF2746 PF10874.3 EPY52596.1 - 0.11 12.6 3.5 0.14 12.3 0.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) DUF3646 PF12362.3 EPY52596.1 - 0.53 10.2 7.7 0.053 13.4 1.4 2.3 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal DUF4140 PF13600.1 EPY52596.1 - 0.74 10.3 0.0 0.74 10.3 0.0 4.6 3 2 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.20 EPY52597.1 - 1.4e-69 234.1 0.0 2.2e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52597.1 - 1e-40 139.4 0.0 1.5e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY52597.1 - 2.3e-08 33.3 0.0 4.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPY52597.1 - 0.0019 17.3 0.0 0.0048 15.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EPY52598.1 - 1.4e-29 100.8 15.5 2.1e-07 30.5 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EPY52598.1 - 1.7e-26 91.9 0.2 3.6e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain G-patch PF01585.18 EPY52599.1 - 9.7e-14 50.8 0.8 2.9e-13 49.3 0.6 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPY52599.1 - 8e-06 25.6 0.1 8e-06 25.6 0.1 4.6 3 1 1 4 4 4 1 DExH-box splicing factor binding site DUF936 PF06075.7 EPY52599.1 - 0.045 12.6 24.9 0.048 12.5 17.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF572 PF04502.8 EPY52599.1 - 2.2 7.4 41.4 3.1 6.9 28.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 EPY52599.1 - 6.1 4.3 32.1 8.1 3.9 22.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoporin_C PF03177.9 EPY52600.1 - 2.9e-101 339.8 11.9 4.2e-101 339.2 8.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPY52600.1 - 9.8e-81 271.6 6.9 2e-80 270.6 4.8 1.5 1 0 0 1 1 1 1 Nup133 N terminal like Methyltransf_31 PF13847.1 EPY52601.1 - 3.9e-14 52.4 0.0 7.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY52601.1 - 3.3e-12 46.7 0.0 1.9e-11 44.2 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.8 EPY52601.1 - 6.2e-12 45.2 0.0 8.6e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EPY52601.1 - 2.1e-10 40.6 0.0 4.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY52601.1 - 3.6e-10 40.4 0.1 1.5e-09 38.4 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY52601.1 - 1.3e-08 34.7 0.0 1.1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY52601.1 - 8.1e-07 29.3 0.0 8.9e-06 26.0 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY52601.1 - 9.9e-07 29.1 0.0 7.5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPY52601.1 - 1.5e-06 27.7 0.1 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EPY52601.1 - 3.3e-06 26.0 0.1 4.8e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 EPY52601.1 - 4.3e-06 25.9 0.0 5.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 EPY52601.1 - 7e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EPY52601.1 - 0.00031 20.8 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 EPY52601.1 - 0.0015 19.3 0.0 0.0039 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPY52601.1 - 0.0029 16.8 0.1 0.011 14.9 0.1 2.0 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EPY52601.1 - 0.0046 16.4 0.1 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EPY52601.1 - 0.0067 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EPY52601.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 EPY52601.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 EPY52601.1 - 0.053 13.0 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EPY52601.1 - 0.066 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_L31e PF01198.14 EPY52602.1 - 1.1e-35 121.0 1.9 1.4e-35 120.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TPT PF03151.11 EPY52603.1 - 1.5e-35 122.1 11.4 1.5e-35 122.1 7.9 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPY52603.1 - 3e-10 39.5 27.6 4.9e-10 38.8 19.1 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPY52603.1 - 5.3e-09 36.1 35.0 7e-06 26.1 6.9 2.8 2 2 1 3 3 3 2 EamA-like transporter family PsaX PF08078.7 EPY52603.1 - 0.024 14.5 0.1 0.092 12.6 0.1 2.1 1 0 0 1 1 1 0 PsaX family Endomucin PF07010.7 EPY52603.1 - 0.28 10.4 0.9 0.49 9.6 0.7 1.4 1 0 0 1 1 1 0 Endomucin DUF2530 PF10745.4 EPY52603.1 - 2.6 8.1 5.4 0.44 10.5 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Potass_KdpF PF09604.5 EPY52603.1 - 4.1 7.3 10.5 4.2 7.3 0.6 3.5 3 0 0 3 3 3 0 F subunit of K+-transporting ATPase (Potass_KdpF) DJ-1_PfpI PF01965.19 EPY52604.1 - 2.3e-29 101.7 0.0 2.8e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EPY52604.1 - 3.2e-14 52.5 0.0 4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DUF2124 PF09897.4 EPY52604.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) RRM_1 PF00076.17 EPY52605.1 - 5.8e-17 61.0 0.0 1.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52605.1 - 4e-12 45.9 0.0 1.5e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52605.1 - 0.03 14.1 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ldh_1_C PF02866.13 EPY52605.1 - 0.085 12.5 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain LHH PF14411.1 EPY52605.1 - 0.091 12.9 0.8 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH TSP_C PF05735.7 EPY52605.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Thrombospondin C-terminal region Rer1 PF03248.8 EPY52606.1 - 6.4e-74 247.3 6.0 7.2e-74 247.1 4.1 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 EPY52606.1 - 0.00095 18.6 3.6 0.0012 18.3 2.5 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4400 PF14348.1 EPY52606.1 - 0.11 11.8 0.2 0.11 11.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) DUF237 PF03072.9 EPY52607.1 - 0.032 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 MG032/MG096/MG288 family 1 Sod_Cu PF00080.15 EPY52607.1 - 0.063 13.4 0.0 2.5 8.2 0.0 2.2 1 1 0 1 1 1 0 Copper/zinc superoxide dismutase (SODC) Glyco_transf_34 PF05637.7 EPY52608.1 - 9e-81 270.8 0.1 1.3e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 EPY52608.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PE_PPE_C PF12484.3 EPY52608.1 - 0.15 12.9 0.7 0.26 12.2 0.5 1.3 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal LRR_6 PF13516.1 EPY52609.1 - 2e-11 42.6 3.9 0.068 13.2 0.1 6.7 7 1 1 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EPY52609.1 - 4e-06 26.3 8.2 0.17 11.5 2.2 5.1 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPY52609.1 - 1.9e-05 24.0 4.9 14 6.1 0.0 6.6 5 2 1 6 6 6 1 Leucine Rich Repeat Gcd10p PF04189.8 EPY52609.1 - 0.27 10.3 2.5 0.37 9.8 1.7 1.2 1 0 0 1 1 1 0 Gcd10p family LRR_7 PF13504.1 EPY52609.1 - 0.53 10.7 6.5 83 4.0 0.0 5.8 6 0 0 6 6 6 0 Leucine rich repeat UAF_Rrn10 PF05234.6 EPY52610.1 - 5.1e-20 71.7 0.0 6.4e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 CENP-M PF11111.3 EPY52610.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) Peptidase_S8 PF00082.17 EPY52611.1 - 9.6e-56 188.9 0.2 1.3e-55 188.5 0.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EPY52611.1 - 4.1e-25 87.3 0.0 1.2e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 Proprotein convertase P-domain COX15-CtaA PF02628.10 EPY52612.1 - 2.3e-95 318.9 10.9 2.8e-95 318.6 7.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fer2 PF00111.22 EPY52612.1 - 1.2e-12 47.4 0.3 2e-12 46.6 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF3353 PF11833.3 EPY52612.1 - 3.3 7.1 7.3 0.92 8.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) PHD PF00628.24 EPY52613.1 - 3.5e-09 36.2 9.5 6.6e-09 35.3 6.6 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EPY52613.1 - 1.1e-06 29.0 1.0 1.1e-05 25.8 0.0 3.0 3 1 0 3 3 3 1 SET domain PHD_2 PF13831.1 EPY52613.1 - 0.0026 17.0 5.0 0.0056 15.9 3.5 1.5 1 0 0 1 1 1 1 PHD-finger Ribosomal_L24e PF01246.15 EPY52614.1 - 4.3e-36 122.6 2.7 4.3e-36 122.6 1.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2218 PF09981.4 EPY52614.1 - 0.035 14.2 0.2 0.063 13.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) DUF2175 PF09943.4 EPY52614.1 - 0.067 13.2 0.7 0.17 11.9 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) HGTP_anticodon2 PF12745.2 EPY52614.1 - 0.74 8.9 4.9 0.7 8.9 2.8 1.4 1 1 0 1 1 1 0 Anticodon binding domain of tRNAs Pkinase PF00069.20 EPY52615.1 - 3.4e-65 219.7 0.0 6e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52615.1 - 2.3e-26 92.4 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPY52615.1 - 3.7e-10 40.1 3.2 3.7e-10 40.1 2.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPY52615.1 - 1.2e-07 31.0 0.0 1.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPY52615.1 - 0.0017 18.0 0.0 0.0035 17.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPY52615.1 - 0.02 13.9 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.22 EPY52616.1 - 4.1e-29 101.7 0.1 7.1e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EPY52616.1 - 5.1e-17 61.3 0.2 1.1e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EPY52616.1 - 6.1e-07 28.7 0.4 1.5e-06 27.5 0.3 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 EPY52616.1 - 0.0029 16.6 0.1 0.0078 15.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4135) ArfGap PF01412.13 EPY52617.1 - 4.7e-33 113.4 0.3 4.7e-33 113.4 0.2 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF4253 PF14062.1 EPY52617.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) GCIP PF13324.1 EPY52618.1 - 4.2e-05 22.9 0.1 6.2e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DASH_Dad2 PF08654.5 EPY52618.1 - 0.071 13.1 1.1 0.36 10.8 0.3 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 Myb_DNA-binding PF00249.26 EPY52619.1 - 2.2e-07 30.8 0.4 7.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSF_DNA-bind PF00447.12 EPY52620.1 - 1.6e-34 118.1 0.3 3.5e-34 117.1 0.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Tubulin PF00091.20 EPY52621.1 - 1.5e-70 237.4 0.0 2e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPY52621.1 - 2.7e-49 166.3 0.0 4.6e-49 165.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPY52621.1 - 0.0021 17.5 0.0 0.0058 16.1 0.0 1.8 1 0 0 1 1 1 1 Tubulin domain Pet191_N PF10203.4 EPY52622.1 - 4.9e-23 80.9 6.3 5.7e-23 80.7 4.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EPY52622.1 - 0.013 15.4 2.1 0.013 15.4 1.5 1.9 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.5 EPY52622.1 - 0.26 11.0 5.0 3 7.6 0.8 2.6 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like MFS_1 PF07690.11 EPY52623.1 - 8.5e-46 156.2 53.8 1.6e-45 155.3 35.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY52623.1 - 3.5e-15 55.5 4.7 3.5e-15 55.5 3.2 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EPY52623.1 - 6.5e-09 34.5 17.6 6.5e-09 34.5 12.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DWNN PF08783.6 EPY52623.1 - 0.0068 16.3 0.5 0.014 15.3 0.3 1.4 1 0 0 1 1 1 1 DWNN domain RRM_1 PF00076.17 EPY52624.1 - 6.4e-08 32.1 0.0 1.3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52624.1 - 1.8e-07 31.0 0.0 3.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52624.1 - 3.9e-05 23.4 0.0 8.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF773 PF05600.7 EPY52624.1 - 0.016 14.0 0.4 0.022 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) DUF3886 PF13025.1 EPY52624.1 - 0.076 12.9 7.4 0.12 12.3 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) UFD1 PF03152.9 EPY52625.1 - 2.9e-71 238.2 0.0 3.9e-71 237.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Stm1_N PF09598.5 EPY52626.1 - 1.6e-13 51.1 7.4 1.6e-13 51.1 5.1 4.3 3 1 0 3 3 3 1 Stm1 Whi5 PF08528.6 EPY52628.1 - 2.6e-07 30.0 0.3 6.5e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Whi5 like A_deamin PF02137.13 EPY52629.1 - 4.6e-65 220.1 0.2 6e-65 219.8 0.2 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain WD40 PF00400.27 EPY52630.1 - 5.7e-33 111.6 3.9 2.5e-08 33.4 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat MRP-S25 PF13741.1 EPY52631.1 - 2.7e-67 226.6 11.9 2.3e-62 210.4 4.5 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 CCDC144C PF14915.1 EPY52631.1 - 0.031 13.2 2.1 0.049 12.5 1.5 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region MRP-S23 PF10484.4 EPY52631.1 - 1.3 8.9 8.3 0.31 10.9 2.9 2.2 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.1 EPY52632.1 - 0.00047 20.0 0.2 2.9 7.9 0.0 4.2 3 1 1 4 4 4 1 PPR repeat family PPR PF01535.15 EPY52632.1 - 0.0045 16.8 0.2 36 4.6 0.0 3.8 3 0 0 3 3 3 2 PPR repeat UDG PF03167.14 EPY52633.1 - 1.1e-18 67.1 0.0 1.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ADH_zinc_N PF00107.21 EPY52634.1 - 7.4e-17 61.1 0.1 1.6e-16 60.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPY52634.1 - 2.9e-14 54.0 0.0 6.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPY52634.1 - 2.7e-11 43.2 0.0 9.2e-11 41.4 0.0 1.7 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPY52634.1 - 0.0002 20.9 0.1 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 EPY52634.1 - 0.00048 20.1 0.1 0.001 19.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EPY52634.1 - 0.0016 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.16 EPY52634.1 - 0.0018 17.9 0.4 0.003 17.1 0.3 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Eno-Rase_NADH_b PF12242.3 EPY52634.1 - 0.013 15.3 0.3 0.036 13.8 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPY52634.1 - 0.032 13.3 0.2 0.063 12.3 0.0 1.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Septin PF00735.13 EPY52635.1 - 7.9e-105 349.8 0.0 1.1e-104 349.4 0.0 1.1 1 0 0 1 1 1 1 Septin TPR_11 PF13414.1 EPY52636.1 - 1.4e-41 139.9 20.8 4.3e-15 55.1 0.8 5.7 4 2 1 6 6 6 4 TPR repeat TPR_1 PF00515.23 EPY52636.1 - 1.1e-31 107.1 22.5 1.1e-06 28.0 0.0 7.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52636.1 - 4.7e-31 104.1 22.7 5.4e-08 32.1 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat DnaJ PF00226.26 EPY52636.1 - 1.3e-28 98.4 3.3 2.4e-28 97.6 0.4 2.9 3 0 0 3 3 3 1 DnaJ domain TPR_16 PF13432.1 EPY52636.1 - 3.6e-18 65.7 15.8 1.9e-06 28.4 0.1 5.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52636.1 - 8.4e-16 57.0 9.8 0.0023 18.3 0.0 7.9 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52636.1 - 1.3e-15 57.0 16.8 1.8e-06 27.7 0.1 5.8 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52636.1 - 3.7e-13 49.6 16.4 0.00047 20.4 0.1 5.9 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EPY52636.1 - 1.8e-11 42.9 23.6 0.0006 19.3 0.0 7.3 8 0 0 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EPY52636.1 - 1.9e-09 37.5 9.7 0.003 17.6 0.3 4.4 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EPY52636.1 - 9.1e-08 31.7 12.5 0.048 13.8 0.1 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPY52636.1 - 5.5e-07 29.3 3.1 0.12 12.2 0.0 4.2 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EPY52636.1 - 5.2e-06 25.7 10.1 0.013 14.5 0.4 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY52636.1 - 0.00015 21.2 15.2 0.93 9.4 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat MIT PF04212.13 EPY52636.1 - 0.00049 19.9 12.5 0.84 9.5 0.3 4.9 5 1 1 6 6 5 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EPY52636.1 - 0.0016 18.7 20.0 0.12 12.8 0.0 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat NYD-SP12_N PF15015.1 EPY52636.1 - 0.0043 15.3 0.1 0.02 13.1 0.0 1.9 2 0 0 2 2 2 1 Spermatogenesis-associated, N-terminal SHNi-TPR PF10516.4 EPY52636.1 - 0.0096 15.1 0.8 17 4.7 0.0 4.1 4 0 0 4 4 4 0 SHNi-TPR TPR_10 PF13374.1 EPY52636.1 - 0.016 15.1 6.6 2.8 7.9 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPY52636.1 - 0.19 11.5 7.2 1.3 8.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EPY52636.1 - 0.64 9.9 17.7 0.44 10.4 0.4 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPY52636.1 - 1.7 8.8 9.5 1.4 9.1 0.0 3.7 3 1 0 4 4 3 0 Tetratricopeptide repeat Ku PF02735.11 EPY52637.1 - 6.8e-42 143.1 0.2 1.3e-41 142.2 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EPY52637.1 - 1.7e-37 129.0 0.2 4.5e-37 127.6 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EPY52637.1 - 7.9e-07 29.0 0.0 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like NPR3 PF03666.8 EPY52638.1 - 9e-117 390.3 7.6 3.5e-116 388.4 5.3 1.8 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 HCO3_cotransp PF00955.16 EPY52639.1 - 1.4e-60 205.4 11.4 8.2e-36 123.7 2.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family Rota_NSP4 PF01452.11 EPY52639.1 - 0.11 11.8 0.2 0.26 10.5 0.2 1.6 1 0 0 1 1 1 0 Rotavirus non structural protein DEAD PF00270.24 EPY52640.1 - 1.3e-42 145.1 0.0 4e-42 143.5 0.0 1.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY52640.1 - 1.5e-26 92.0 0.1 3.4e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY52640.1 - 0.0002 21.2 0.0 0.00071 19.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 EPY52641.1 - 1.3e-58 198.1 0.0 1.7e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52641.1 - 1.1e-36 126.2 0.0 1.4e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY52641.1 - 2.4e-07 30.0 0.0 3.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EPY52641.1 - 0.072 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EPY52641.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Scs3p PF10261.4 EPY52642.1 - 7.3e-52 175.7 26.0 1.6e-49 168.1 18.0 2.2 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Peptidase_M41 PF01434.13 EPY52643.1 - 3.8e-74 248.7 0.4 5.5e-74 248.2 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPY52643.1 - 2.1e-42 144.4 0.0 5.2e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EPY52643.1 - 1.8e-12 47.4 0.1 4.9e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EPY52643.1 - 0.00078 20.2 0.0 0.003 18.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPY52643.1 - 0.00095 18.9 0.0 0.0079 15.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPY52643.1 - 0.003 17.2 0.2 0.0081 15.8 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EPY52643.1 - 0.0037 16.3 0.0 0.03 13.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPY52643.1 - 0.004 17.3 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EPY52643.1 - 0.0043 15.8 0.0 0.0076 15.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EPY52643.1 - 0.0061 16.5 0.2 0.064 13.2 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 EPY52643.1 - 0.0096 15.0 0.1 0.056 12.5 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 EPY52643.1 - 0.018 14.9 0.0 0.089 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EPY52643.1 - 0.029 13.7 0.1 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EPY52643.1 - 0.052 12.9 0.5 0.16 11.3 0.2 1.8 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EPY52643.1 - 0.07 13.0 0.3 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EPY52643.1 - 0.16 11.5 0.1 9.2 5.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain CHD5 PF04420.9 EPY52644.1 - 2.8e-43 147.3 7.2 3.4e-43 147.0 5.0 1.0 1 0 0 1 1 1 1 CHD5-like protein NAGLU_C PF12972.2 EPY52644.1 - 0.018 14.4 1.1 0.026 13.9 0.8 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DUF2856 PF11043.3 EPY52644.1 - 0.56 10.3 2.4 0.4 10.8 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) Nuc_sug_transp PF04142.10 EPY52645.1 - 4.1e-09 35.9 0.3 4.1e-09 35.9 0.2 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF914 PF06027.7 EPY52645.1 - 0.00033 19.6 3.6 0.00033 19.6 2.5 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EPY52645.1 - 0.00077 19.5 5.3 0.00077 19.5 3.7 3.2 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EPY52645.1 - 0.00084 19.5 3.1 0.00084 19.5 2.1 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EPY52645.1 - 0.01 15.6 0.7 0.01 15.6 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EPY52645.1 - 0.019 14.6 17.7 0.13 11.9 7.0 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family Pox_E8 PF03394.8 EPY52645.1 - 0.046 13.0 0.2 0.046 13.0 0.1 1.6 2 0 0 2 2 2 0 Poxvirus E8 protein TrbC PF04956.8 EPY52645.1 - 0.23 11.4 15.1 0.44 10.5 2.6 2.8 3 0 0 3 3 3 0 TrbC/VIRB2 family NTP_transf_2 PF01909.18 EPY52646.1 - 1.3e-13 51.1 0.0 5.4e-13 49.0 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EPY52646.1 - 7.8e-13 48.1 0.0 2.5e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase WD40 PF00400.27 EPY52647.1 - 5.9e-58 190.8 13.3 6.8e-10 38.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPY52647.1 - 5.8e-07 29.4 0.4 0.16 11.6 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPY52647.1 - 0.013 13.7 0.2 3.1 5.7 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF155 PF02582.9 EPY52648.1 - 2.5e-55 187.0 0.0 4.4e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 XPG_I PF00867.13 EPY52649.1 - 2.9e-15 56.0 0.2 3.5e-14 52.6 0.0 2.4 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EPY52649.1 - 1.7e-12 47.4 0.1 4.9e-05 23.5 0.0 2.7 1 1 1 2 2 2 2 XPG N-terminal domain DUF2458 PF10454.4 EPY52649.1 - 0.032 14.1 0.1 0.032 14.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) PseudoU_synth_2 PF00849.17 EPY52650.1 - 5.4e-30 104.3 0.0 8e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Rad50_zn_hook PF04423.9 EPY52650.1 - 0.0041 16.5 0.1 0.01 15.2 0.1 1.6 1 0 0 1 1 1 1 Rad50 zinc hook motif Auto_anti-p27 PF06677.7 EPY52650.1 - 0.0052 16.5 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DNA_ligase_ZBD PF03119.11 EPY52650.1 - 0.059 13.0 0.8 0.13 11.9 0.6 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain GFA PF04828.9 EPY52650.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme EF-hand_1 PF00036.27 EPY52651.1 - 7.2e-26 87.4 9.4 1.7e-07 30.0 0.1 5.0 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.1 EPY52651.1 - 9.9e-25 84.1 3.9 1e-06 28.1 0.1 4.9 4 1 2 6 6 6 4 EF-hand domain EF-hand_7 PF13499.1 EPY52651.1 - 2.8e-23 81.8 4.0 3.5e-14 52.6 0.3 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPY52651.1 - 1.3e-17 62.2 7.6 6e-06 25.3 0.2 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EPY52651.1 - 6.5e-14 51.2 9.4 1.9e-05 24.1 0.7 4.4 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EPY52651.1 - 1.5e-06 27.8 8.5 0.38 10.5 0.1 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPY52651.1 - 0.0002 21.1 1.3 0.053 13.4 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EPY52651.1 - 0.00031 20.7 2.5 0.086 12.8 0.1 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 EPY52651.1 - 0.00098 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_10 PF14788.1 EPY52651.1 - 0.021 14.4 3.9 22 4.7 0.0 3.8 3 1 0 3 3 3 0 EF hand EF-hand_2 PF09068.6 EPY52651.1 - 0.021 14.8 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 EF hand RMMBL PF07521.7 EPY52651.1 - 0.063 13.1 0.2 21 5.0 0.0 3.3 3 1 1 4 4 4 0 RNA-metabolising metallo-beta-lactamase DUF1679 PF07914.6 EPY52651.1 - 0.11 11.0 0.3 8.4 4.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pam16 PF03656.8 EPY52651.1 - 0.91 9.3 3.2 8.4 6.2 0.0 2.9 2 1 0 2 2 2 0 Pam16 Mannosyl_trans2 PF04188.8 EPY52652.1 - 8.9e-85 285.2 42.8 1.8e-83 280.9 29.7 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) 60KD_IMP PF02096.15 EPY52652.1 - 1.8 8.1 15.5 1.4 8.4 1.1 3.8 3 2 1 4 4 4 0 60Kd inner membrane protein Sas10_Utp3 PF04000.10 EPY52653.1 - 2.4e-08 34.0 3.8 8.1e-08 32.3 2.3 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CDV3 PF15359.1 EPY52653.1 - 0.0034 17.4 0.1 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Curto_V2 PF07325.6 EPY52653.1 - 2.2 7.9 4.6 1.8 8.2 0.2 2.6 3 0 0 3 3 3 0 Curtovirus V2 protein UQ_con PF00179.21 EPY52654.1 - 1e-50 170.8 0.0 1.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPY52654.1 - 1.9e-06 27.6 0.0 2.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPY52654.1 - 0.023 14.6 0.1 0.032 14.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EPY52654.1 - 0.052 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain UPF0139 PF03669.8 EPY52655.1 - 2.9e-08 33.1 1.0 4.1e-08 32.6 0.7 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) WD40 PF00400.27 EPY52656.1 - 8.2e-72 234.7 13.9 4.3e-12 45.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EPY52656.1 - 9.6e-16 57.7 4.6 9.6e-16 57.7 3.2 2.1 2 0 0 2 2 2 1 Tup N-terminal eIF2A PF08662.6 EPY52656.1 - 3.3e-08 33.4 0.0 1.2e-05 25.1 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPY52656.1 - 6.1e-08 31.2 1.9 0.093 10.8 0.0 4.9 1 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPY52656.1 - 3.2e-06 26.1 9.1 0.012 14.4 0.1 5.1 2 1 2 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 EPY52656.1 - 0.00013 21.5 0.7 6.2 6.6 0.0 5.7 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EPY52656.1 - 0.0017 16.7 0.1 0.12 10.6 0.0 2.7 2 1 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EPY52656.1 - 0.01 15.2 0.1 0.18 11.1 0.0 2.5 3 0 0 3 3 3 0 PQQ-like domain EAP30 PF04157.11 EPY52656.1 - 5.5 6.0 10.1 0.067 12.3 0.4 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family DUF3384 PF11864.3 EPY52657.1 - 1.1e-54 185.7 16.1 2.3e-54 184.6 11.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Thioredoxin PF00085.15 EPY52658.1 - 4.4e-68 225.5 3.4 6.8e-31 106.0 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EPY52658.1 - 7.1e-45 153.0 5.8 1.5e-29 103.1 0.6 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EPY52658.1 - 8e-14 51.7 2.5 1.4e-05 25.2 0.0 4.6 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EPY52658.1 - 1.5e-12 47.3 1.4 1.7e-06 27.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EPY52658.1 - 8.1e-11 41.9 5.5 7.2e-05 22.8 0.0 5.3 4 2 2 6 6 6 2 Thioredoxin-like Calsequestrin PF01216.12 EPY52658.1 - 6.4e-10 38.3 4.3 9.1e-09 34.5 0.6 2.2 1 1 1 2 2 2 2 Calsequestrin AhpC-TSA PF00578.16 EPY52658.1 - 2.2e-08 33.8 2.3 0.003 17.2 0.0 3.3 2 1 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EPY52658.1 - 5.6e-06 25.9 2.0 0.002 17.7 0.0 3.2 3 0 0 3 3 3 1 Redoxin Thioredoxin_4 PF13462.1 EPY52658.1 - 0.01 15.8 5.7 0.022 14.7 0.3 3.3 3 1 0 3 3 3 0 Thioredoxin Thioredoxin_9 PF14595.1 EPY52658.1 - 0.03 13.8 0.3 3.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin DAO PF01266.19 EPY52659.1 - 7e-47 160.0 0.0 8.1e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPY52659.1 - 0.00018 21.3 0.0 0.00091 19.0 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPY52659.1 - 0.0054 16.7 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPY52659.1 - 0.0069 16.2 0.0 0.26 11.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPY52659.1 - 0.046 13.7 0.0 0.27 11.2 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FH2 PF02181.18 EPY52660.1 - 4.9e-77 259.3 5.8 1.5e-76 257.6 4.0 1.8 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EPY52660.1 - 4.2e-20 71.9 3.9 4.2e-20 71.9 2.7 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EPY52660.1 - 2.3e-12 46.6 0.0 2.3e-12 46.6 0.0 3.3 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Mso1_Sec1_bdg PF14475.1 EPY52661.1 - 1.2e-11 43.8 0.0 2.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Mso1_C PF14477.1 EPY52661.1 - 0.011 16.0 4.9 0.011 16.0 3.4 2.2 1 1 1 2 2 2 0 Membrane-polarising domain of Mso1 Axin_b-cat_bind PF08833.5 EPY52661.1 - 0.012 15.2 0.1 0.012 15.2 0.0 2.6 2 1 0 2 2 2 0 Axin beta-catenin binding domain HSP70 PF00012.15 EPY52662.1 - 2.8e-60 203.8 0.2 2.8e-60 203.8 0.1 2.5 3 0 0 3 3 3 2 Hsp70 protein FGGY_C PF02782.11 EPY52662.1 - 0.016 14.8 0.0 0.047 13.3 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Mit_ribos_Mrp51 PF11709.3 EPY52662.1 - 0.39 9.8 8.9 0.22 10.7 4.5 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit Amino_oxidase PF01593.19 EPY52663.1 - 2e-18 66.7 0.0 6.7e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPY52663.1 - 4.3e-10 39.4 0.0 2.1e-09 37.2 0.0 2.1 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPY52663.1 - 6.4e-06 25.3 0.0 1.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPY52663.1 - 0.15 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Mid1 PF12929.2 EPY52664.1 - 1.6e-106 356.6 18.9 2.2e-106 356.1 13.1 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component PP2 PF14299.1 EPY52664.1 - 0.026 13.9 0.1 0.058 12.7 0.1 1.6 1 0 0 1 1 1 0 Phloem protein 2 Fz PF01392.17 EPY52664.1 - 0.16 12.3 1.7 2 8.7 0.2 2.4 2 0 0 2 2 2 0 Fz domain Pkinase PF00069.20 EPY52665.1 - 8e-71 238.2 0.9 1.2e-70 237.6 0.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52665.1 - 5.1e-57 192.9 0.4 7.3e-57 192.3 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EPY52665.1 - 9.5e-12 45.1 0.0 3.5e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EPY52665.1 - 7.1e-11 42.2 3.2 7.1e-11 42.2 2.2 2.4 2 1 0 2 2 2 1 PH domain Kinase-like PF14531.1 EPY52665.1 - 3e-10 39.5 0.0 5.9e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPY52665.1 - 1.2e-05 24.4 1.4 2.2e-05 23.6 1.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.1 EPY52665.1 - 0.008 16.4 4.3 0.039 14.2 3.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Seadorna_VP7 PF07387.6 EPY52665.1 - 0.0083 14.9 0.1 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EPY52665.1 - 0.0089 15.7 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family NDK PF00334.14 EPY52666.1 - 3.8e-55 185.3 0.0 4.3e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GCP5-Mod21 PF14609.1 EPY52667.1 - 3.3e-42 144.4 17.7 7.2e-27 93.8 7.8 2.1 1 1 0 2 2 2 2 gamma-Tubulin ring complex non-core subunit mod21 DUF3791 PF12668.2 EPY52667.1 - 0.03 13.9 0.1 0.23 11.1 0.1 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) ELO PF01151.13 EPY52668.1 - 1.3e-48 165.5 24.9 1.5e-48 165.2 17.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family TrkH PF02386.11 EPY52669.1 - 1e-108 363.1 12.1 1.7e-108 362.3 4.9 2.0 2 0 0 2 2 2 2 Cation transport protein FAT PF02259.18 EPY52670.1 - 1.5e-69 234.6 11.8 2.9e-69 233.7 8.2 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EPY52670.1 - 9.1e-30 103.8 2.6 1.3e-29 103.3 0.3 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPY52670.1 - 1.2e-11 43.8 3.3 1.8e-09 36.8 0.8 2.6 2 0 0 2 2 2 2 FATC domain DEAD PF00270.24 EPY52671.1 - 4.9e-43 146.5 0.3 9.8e-43 145.5 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY52671.1 - 4.5e-30 103.3 0.1 1.5e-29 101.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EPY52671.1 - 0.00049 19.8 0.2 0.0015 18.2 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain Helicase_C_2 PF13307.1 EPY52671.1 - 0.0053 16.7 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain DUF1253 PF06862.7 EPY52671.1 - 0.014 13.8 0.0 0.099 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 EPY52671.1 - 0.019 14.5 0.2 0.059 12.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPY52671.1 - 0.029 14.5 0.7 0.22 11.6 0.5 2.2 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EPY52671.1 - 0.064 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ResIII PF04851.10 EPY52671.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CTP_transf_2 PF01467.21 EPY52672.1 - 6.3e-31 107.5 0.0 8.5e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase TALPID3 PF15324.1 EPY52672.1 - 2.1 5.5 5.9 2.7 5.2 4.1 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Complex1_LYR PF05347.10 EPY52673.1 - 5.1e-06 26.1 1.1 8.9e-06 25.4 0.2 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Ribosomal_L14e PF01929.12 EPY52674.1 - 8.9e-27 93.2 1.6 1.3e-26 92.7 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EPY52674.1 - 1.5e-05 24.5 0.6 2.6e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 KOW motif Ribosomal_S26e PF01283.14 EPY52675.1 - 6.9e-52 174.5 8.7 7.7e-52 174.3 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e WD40 PF00400.27 EPY52676.1 - 2.5e-60 198.3 21.9 3.5e-14 52.0 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ParA PF10609.4 EPY52676.1 - 5.3e-37 125.5 0.2 1e-36 124.6 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EPY52676.1 - 1.6e-12 47.2 0.0 2.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain eIF2A PF08662.6 EPY52676.1 - 4.7e-05 23.1 0.0 0.011 15.4 0.0 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPY52676.1 - 0.00018 19.4 0.3 0.15 9.8 0.0 2.1 2 0 0 2 2 2 2 IKI3 family Apc4_WD40 PF12894.2 EPY52676.1 - 0.00021 20.7 0.0 0.24 10.9 0.0 3.9 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain ArsA_ATPase PF02374.10 EPY52676.1 - 0.00063 18.8 0.2 0.011 14.7 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EPY52676.1 - 0.0032 16.6 0.0 0.014 14.4 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EPY52676.1 - 0.012 14.9 0.0 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.1 EPY52676.1 - 0.014 15.2 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain zf-C4_ClpX PF06689.8 EPY52676.1 - 0.088 12.3 1.7 0.25 10.9 1.2 1.7 1 0 0 1 1 1 0 ClpX C4-type zinc finger DUF258 PF03193.11 EPY52676.1 - 0.095 11.8 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPY52676.1 - 0.096 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Porphobil_deam PF01379.15 EPY52677.1 - 5.6e-81 270.5 0.0 7.9e-81 270.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EPY52677.1 - 4.4e-17 61.9 0.0 8e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain E1-E2_ATPase PF00122.15 EPY52678.1 - 1.3e-15 57.0 0.0 3.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EPY52678.1 - 5.2e-13 49.5 0.0 1.3e-12 48.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY52678.1 - 4.9e-10 39.2 0.0 1.7e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EPY52678.1 - 1.6e-09 38.4 0.7 1.1e-07 32.4 0.5 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPY52678.1 - 0.0038 16.8 0.2 0.0087 15.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EPY52679.1 - 3.6e-60 203.2 0.1 2.5e-59 200.5 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52679.1 - 2.1e-28 99.1 0.2 9.3e-21 74.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EPY52679.1 - 2.6e-05 24.6 3.1 3.6e-05 24.1 0.5 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPY52679.1 - 0.0003 19.8 0.2 0.011 14.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPY52679.1 - 0.0011 18.7 0.0 1.7 8.2 0.0 2.9 1 1 2 3 3 3 2 Phosphotransferase enzyme family Sel1 PF08238.7 EPY52680.1 - 4e-40 135.3 4.8 2.2e-07 31.3 0.4 7.5 7 0 0 7 7 7 6 Sel1 repeat MPC PF03650.8 EPY52681.1 - 3.9e-47 159.1 1.3 4.5e-47 158.9 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) COPIIcoated_ERV PF07970.7 EPY52682.1 - 6.6e-64 215.5 0.0 9.5e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPY52682.1 - 4.8e-32 109.7 0.1 4.8e-32 109.7 0.0 1.8 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) H_lectin PF09458.5 EPY52682.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 H-type lectin domain ApbA PF02558.11 EPY52683.1 - 4.3e-08 32.7 0.0 7.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPY52683.1 - 5.8e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pkinase PF00069.20 EPY52684.1 - 3.4e-72 242.7 0.0 4.2e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52684.1 - 7.7e-32 110.3 0.0 9.6e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPY52684.1 - 8.5e-05 21.7 0.1 0.00034 19.7 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPY52684.1 - 0.00059 19.6 0.1 0.0019 18.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY52684.1 - 0.011 14.7 0.0 0.37 9.7 0.0 2.2 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.17 EPY52684.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HAD_2 PF13419.1 EPY52685.1 - 1.1e-28 100.6 0.6 1.4e-28 100.2 0.4 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY52685.1 - 2.3e-05 24.8 0.0 0.00012 22.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPY52685.1 - 0.0001 21.9 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EPY52685.1 - 0.012 15.3 0.0 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase NIF PF03031.13 EPY52685.1 - 0.024 14.3 0.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase PNK3P PF08645.6 EPY52685.1 - 0.08 12.3 0.1 0.44 9.9 0.1 2.3 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Calcipressin PF04847.7 EPY52686.1 - 4.7e-31 107.8 0.0 5.9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Calcipressin NUDIX PF00293.23 EPY52687.1 - 2e-13 50.1 0.1 4.4e-13 49.0 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Chitin_synth_1 PF01644.12 EPY52688.1 - 8.5e-85 282.5 0.2 1.3e-84 281.9 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPY52688.1 - 7.7e-29 99.2 0.1 1.6e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPY52688.1 - 3e-27 95.2 1.5 7.2e-19 67.5 0.0 2.6 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPY52688.1 - 1e-10 41.6 0.2 1e-10 41.6 0.2 2.7 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPY52688.1 - 7.3e-09 35.7 0.0 2.7e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GHMP_kinases_N PF00288.21 EPY52689.1 - 1e-18 67.1 0.2 7.8e-18 64.3 0.4 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPY52689.1 - 0.00019 21.5 0.0 0.00065 19.8 0.0 2.0 1 1 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EPY52689.1 - 0.032 13.5 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Glyco_hydro_cc PF11790.3 EPY52690.1 - 1.6e-56 191.4 0.4 2.4e-56 190.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PDCD2_C PF04194.8 EPY52691.1 - 2.9e-34 118.0 0.5 1.7e-32 112.2 0.2 2.1 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Glyco_hydro_68 PF02435.11 EPY52691.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Levansucrase/Invertase Ribosomal_S6e PF01092.14 EPY52692.1 - 1.7e-64 215.1 0.1 3.8e-64 214.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e WD40 PF00400.27 EPY52693.1 - 1.3e-16 59.7 12.8 5.1e-07 29.3 0.0 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EPY52693.1 - 5.1e-08 32.8 1.1 0.00026 20.7 0.5 3.4 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A GDC-P PF02347.11 EPY52694.1 - 2.2e-201 669.1 0.0 2.1e-185 616.5 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EPY52694.1 - 0.0003 19.6 0.1 0.0041 15.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPY52694.1 - 0.00066 18.9 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPY52694.1 - 0.068 11.4 0.0 0.13 10.5 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TRAPP PF04051.11 EPY52695.1 - 1.1e-35 122.3 0.0 1.4e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Phosphodiest PF01663.17 EPY52697.1 - 2.7e-16 59.8 3.7 1.6e-14 54.0 2.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPY52697.1 - 0.0076 15.4 0.5 1.7 7.7 0.0 2.3 1 1 1 2 2 2 2 Sulfatase Ribosomal_S3Ae PF01015.13 EPY52698.1 - 1.5e-78 262.6 2.5 1.8e-78 262.3 1.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SNF2_N PF00176.18 EPY52699.1 - 5.8e-71 238.7 0.0 9.1e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY52699.1 - 2.3e-13 49.8 0.0 5.2e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EPY52699.1 - 6.3e-12 45.3 0.2 2.9e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 HIRAN domain zf-C3HC4_3 PF13920.1 EPY52699.1 - 6.4e-05 22.5 14.6 0.00017 21.2 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY52699.1 - 0.00011 22.2 17.4 0.00032 20.6 12.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EPY52699.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EPY52699.1 - 0.00044 19.8 17.6 0.0012 18.4 12.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY52699.1 - 0.00065 19.4 16.4 0.0014 18.3 11.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPY52699.1 - 0.0087 15.7 15.8 0.02 14.6 11.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain CUE PF02845.11 EPY52699.1 - 0.017 14.5 0.0 0.073 12.5 0.0 2.1 2 0 0 2 2 2 0 CUE domain zf-RING_UBOX PF13445.1 EPY52699.1 - 0.064 12.9 11.3 0.23 11.2 7.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPY52699.1 - 0.094 12.6 16.6 0.21 11.4 11.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3645 PF12359.3 EPY52699.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) Glyco_transf_8 PF01501.15 EPY52702.1 - 1.1e-14 54.3 1.6 7.9e-14 51.5 1.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPY52702.1 - 0.042 13.1 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative Pantoate_transf PF02548.10 EPY52704.1 - 1.7e-103 345.2 0.0 2e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EPY52704.1 - 0.00014 21.2 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.17 EPY52704.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase Pantoate_ligase PF02569.10 EPY52705.1 - 4e-103 344.0 0.0 4.4e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FAD_syn PF06574.7 EPY52705.1 - 0.0045 16.6 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 FAD synthetase CTP_transf_2 PF01467.21 EPY52705.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Oxidored_FMN PF00724.15 EPY52706.1 - 4.3e-113 377.7 0.0 4.8e-113 377.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fe-ADH PF00465.14 EPY52707.1 - 7.7e-122 406.4 0.4 8.8e-122 406.2 0.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPY52707.1 - 5.4e-23 81.5 2.1 1e-20 74.1 0.8 2.3 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase Flavodoxin_2 PF02525.12 EPY52708.1 - 1e-31 110.0 0.0 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 EPY52708.1 - 0.0032 16.8 0.8 0.0059 15.9 0.5 1.5 1 1 0 1 1 1 1 Flavodoxin DUF4146 PF13652.1 EPY52708.1 - 0.0044 16.8 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4146) FMN_red PF03358.10 EPY52708.1 - 0.012 15.1 0.0 0.053 13.0 0.0 1.9 1 1 0 1 1 1 0 NADPH-dependent FMN reductase His_Phos_1 PF00300.17 EPY52709.1 - 5.1e-22 78.6 0.0 6.7e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.11 EPY52710.1 - 3.7e-31 108.1 17.3 3.7e-31 108.1 12.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily HlyIII PF03006.15 EPY52710.1 - 0.63 9.3 18.3 0.48 9.7 3.6 3.0 1 1 2 3 3 3 0 Haemolysin-III related DUF3093 PF11292.3 EPY52710.1 - 3 7.6 4.4 0.61 9.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Fungal_trans PF04082.13 EPY52711.1 - 5.2e-09 35.3 5.1 6.5e-07 28.4 2.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EPY52711.1 - 5.5e-08 32.6 13.6 0.00021 21.3 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPY52711.1 - 1e-07 31.8 15.2 0.00054 20.1 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPY52711.1 - 0.00016 21.4 0.2 0.00016 21.4 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPY52711.1 - 0.035 14.2 0.1 0.035 14.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EPY52711.1 - 0.9 9.9 18.8 2.2 8.7 0.8 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 EPY52711.1 - 8.2 6.8 13.9 0.54 10.6 5.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Hydantoinase_B PF02538.9 EPY52713.1 - 1.9e-202 673.2 0.3 2.7e-202 672.6 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EPY52713.1 - 7.3e-94 314.1 0.1 7.3e-94 314.1 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPY52713.1 - 1.1e-56 191.0 2.2 1.3e-55 187.6 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Ribosomal_L30_N PF08079.7 EPY52714.1 - 4.4e-23 81.0 16.9 8.8e-23 80.1 11.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EPY52714.1 - 9.7e-21 73.1 0.6 2.1e-20 72.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF1501 PF07394.7 EPY52714.1 - 0.16 10.7 0.2 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DNA_pol_B PF00136.16 EPY52715.1 - 7.9e-114 380.9 0.9 1.1e-113 380.5 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPY52715.1 - 1.1e-43 149.3 0.8 1.6e-43 148.8 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 EPY52715.1 - 1.2e-36 125.8 7.8 2.8e-35 121.3 5.4 2.4 1 1 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_alpha_N PF12254.3 EPY52715.1 - 6.1e-24 83.6 9.4 4.7e-23 80.7 5.8 2.7 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal AAR2 PF05282.6 EPY52716.1 - 7.1e-32 110.7 7.3 4.3e-31 108.1 5.1 2.0 1 1 0 1 1 1 1 AAR2 protein DUF3579 PF12112.3 EPY52716.1 - 0.09 12.6 0.6 3.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) Ribosomal_S11 PF00411.14 EPY52717.1 - 1.3e-40 138.0 1.3 1.5e-40 137.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Kinesin PF00225.18 EPY52718.1 - 5.4e-99 331.0 0.2 5.4e-99 331.0 0.1 2.2 2 1 1 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EPY52718.1 - 0.043 13.0 7.8 0.53 9.4 1.4 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EPY52718.1 - 0.11 9.8 37.9 0.18 9.1 26.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Acetyltransf_11 PF13720.1 EPY52718.1 - 3.5 7.9 9.0 7.9 6.7 1.0 4.1 3 1 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Prefoldin_2 PF01920.15 EPY52719.1 - 1e-23 83.1 13.3 1.1e-23 82.9 9.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit Bacillus_HBL PF05791.6 EPY52719.1 - 0.001 18.4 6.5 0.028 13.8 0.8 2.2 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) YkyA PF10368.4 EPY52719.1 - 0.0021 17.4 12.2 0.0028 17.0 8.5 1.1 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein Prefoldin_3 PF13758.1 EPY52719.1 - 0.009 15.7 6.2 0.026 14.2 4.3 1.8 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EPY52719.1 - 0.011 15.3 10.2 0.018 14.6 2.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit HXXSHH PF07586.6 EPY52719.1 - 0.014 14.3 4.0 0.028 13.3 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) Spectrin PF00435.16 EPY52719.1 - 0.014 15.6 3.7 0.029 14.6 2.6 1.5 1 1 0 1 1 1 0 Spectrin repeat Cob_adeno_trans PF01923.13 EPY52719.1 - 0.03 14.1 2.3 0.043 13.6 1.6 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Fib_alpha PF08702.5 EPY52719.1 - 0.037 14.1 2.4 0.037 14.1 1.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ING PF12998.2 EPY52719.1 - 0.045 14.0 3.3 0.074 13.3 2.3 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF1732 PF08340.6 EPY52719.1 - 0.054 13.3 2.6 0.089 12.6 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) ERM PF00769.14 EPY52719.1 - 0.092 12.2 10.0 0.1 12.1 6.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.4 EPY52719.1 - 0.098 11.5 7.3 0.13 11.1 5.1 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-H PF05837.7 EPY52719.1 - 0.13 12.4 6.5 0.11 12.6 3.5 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Peptidase_S46 PF10459.4 EPY52719.1 - 0.17 10.2 7.1 0.17 10.2 4.9 1.0 1 0 0 1 1 1 0 Peptidase S46 Baculo_PEP_C PF04513.7 EPY52719.1 - 0.19 11.5 3.8 4.1 7.2 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EPY52719.1 - 0.22 11.1 10.0 1 8.9 6.9 1.8 1 1 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 EPY52719.1 - 0.25 11.5 8.1 0.18 11.9 0.6 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 EPY52719.1 - 0.31 11.4 5.5 1 9.8 3.5 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF812 PF05667.6 EPY52719.1 - 0.36 9.2 12.9 1.6 7.1 8.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF2408 PF10303.4 EPY52719.1 - 0.36 10.9 6.1 0.96 9.5 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) WXG100 PF06013.7 EPY52719.1 - 0.4 10.7 3.7 1.8 8.5 0.1 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG ADIP PF11559.3 EPY52719.1 - 0.52 10.2 11.3 0.59 10.0 3.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF489 PF04356.7 EPY52719.1 - 0.52 9.8 4.8 0.53 9.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) APG6 PF04111.7 EPY52719.1 - 0.56 9.1 11.4 1.1 8.2 7.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF641 PF04859.7 EPY52719.1 - 0.57 9.9 8.5 0.16 11.7 0.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) YgaB PF14182.1 EPY52719.1 - 0.59 10.4 9.8 0.7 10.1 3.1 2.2 1 1 1 2 2 2 0 YgaB-like protein L31 PF09784.4 EPY52719.1 - 0.66 10.0 4.5 2.1 8.4 0.9 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DivIC PF04977.10 EPY52719.1 - 0.92 9.0 10.7 0.67 9.4 1.5 2.4 2 1 0 2 2 2 0 Septum formation initiator DivIVA PF05103.8 EPY52719.1 - 1.1 9.3 13.2 0.76 9.8 2.7 2.3 1 1 1 2 2 2 0 DivIVA protein Med9 PF07544.8 EPY52719.1 - 1.2 8.9 7.1 5.8 6.7 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Occludin_ELL PF07303.8 EPY52719.1 - 1.2 9.9 6.8 1.1 10.0 2.5 2.0 1 1 1 2 2 2 0 Occludin homology domain Spc24 PF08286.6 EPY52719.1 - 1.4 8.5 10.8 6 6.5 2.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.1 EPY52719.1 - 1.7 7.5 10.4 4.2 6.2 7.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2802 PF10975.3 EPY52719.1 - 2.2 8.0 7.2 0.76 9.5 0.2 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF2802) DUF1843 PF08898.5 EPY52719.1 - 3.3 7.8 9.2 0.85 9.7 0.3 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF1843) AAA_23 PF13476.1 EPY52719.1 - 4.1 7.6 9.7 5.9 7.1 6.8 1.3 1 0 0 1 1 1 0 AAA domain zf-CpG_bind_C PF12269.3 EPY52719.1 - 4.7 6.6 6.6 2 7.8 2.3 1.8 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain CENP-Q PF13094.1 EPY52719.1 - 4.8 7.1 9.2 11 6.0 6.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc42p PF11544.3 EPY52719.1 - 4.9 7.1 8.3 0.52 10.2 0.4 2.7 2 2 0 2 2 2 0 Spindle pole body component Spc42p DUF972 PF06156.8 EPY52719.1 - 4.9 7.5 8.3 7.9 6.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) YojJ PF10372.4 EPY52719.1 - 5.9 6.8 5.8 2.2 8.1 1.4 2.1 2 2 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus TMF_DNA_bd PF12329.3 EPY52719.1 - 6.2 6.7 14.1 6.8 6.5 2.7 2.7 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AAA PF00004.24 EPY52720.1 - 1.1e-41 142.1 0.6 9e-41 139.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPY52720.1 - 1.3e-05 25.2 0.1 0.00013 21.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPY52720.1 - 2.3e-05 24.4 1.4 0.0023 17.9 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EPY52720.1 - 0.0001 22.0 1.2 0.00054 19.7 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPY52720.1 - 0.00094 18.2 0.0 0.0024 16.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EPY52720.1 - 0.0054 16.1 0.0 0.0099 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 EPY52720.1 - 0.0067 15.6 0.0 0.03 13.5 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 EPY52720.1 - 0.0074 16.4 5.1 0.016 15.3 0.2 3.0 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EPY52720.1 - 0.0089 15.9 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPY52720.1 - 0.012 14.7 0.2 0.04 13.0 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPY52720.1 - 0.014 15.1 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EPY52720.1 - 0.025 14.4 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EPY52720.1 - 0.027 13.6 0.1 0.092 11.8 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 EPY52720.1 - 0.028 13.8 1.0 0.2 11.0 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 EPY52720.1 - 0.029 13.9 0.0 0.55 9.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EPY52720.1 - 0.041 12.8 0.0 0.091 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EPY52720.1 - 0.064 12.8 0.1 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3608 PF12257.3 EPY52720.1 - 0.065 12.1 0.6 0.11 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) AAA_17 PF13207.1 EPY52720.1 - 0.096 13.5 0.2 0.36 11.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EPY52720.1 - 0.1 12.1 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EPY52720.1 - 0.13 12.4 0.0 0.55 10.4 0.0 2.2 2 0 0 2 2 1 0 RNA helicase CALCOCO1 PF07888.6 EPY52720.1 - 0.17 10.1 3.8 0.23 9.7 2.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like NACHT PF05729.7 EPY52720.1 - 0.34 10.5 2.5 5.7 6.5 0.0 3.0 2 1 1 3 3 3 0 NACHT domain Aldo_ket_red PF00248.16 EPY52721.1 - 3.5e-36 124.4 0.0 4e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_M19 PF01244.16 EPY52722.1 - 2e-102 342.4 0.0 2.5e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Na_H_Exchanger PF00999.16 EPY52723.1 - 1.7e-79 267.0 23.5 2e-79 266.8 16.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 EPY52723.1 - 0.00066 19.0 9.2 0.00066 19.0 6.4 3.0 2 1 1 3 3 3 2 Alkali metal cation/H+ antiporter Nha1 C terminus YrhC PF14143.1 EPY52723.1 - 0.099 12.5 0.2 0.099 12.5 0.1 2.8 3 0 0 3 3 3 0 YrhC-like protein Cullin PF00888.17 EPY52724.1 - 4.3e-133 444.9 14.4 7.1e-133 444.2 10.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPY52724.1 - 6e-22 77.2 1.4 2.2e-21 75.4 1.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain RPA_C PF08784.6 EPY52724.1 - 0.1 13.0 0.1 4.5 7.7 0.0 2.8 2 0 0 2 2 2 0 Replication protein A C terminal Pyr_redox_2 PF07992.9 EPY52725.1 - 1.4e-27 96.8 0.0 1.9e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPY52725.1 - 6.9e-11 42.4 0.0 4.5e-10 39.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPY52725.1 - 5.3e-06 26.6 0.0 1.5e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PX PF00787.19 EPY52726.1 - 7.4e-19 67.6 2.0 7.4e-19 67.6 1.4 2.7 3 0 0 3 3 3 1 PX domain ComX PF05952.7 EPY52726.1 - 0.075 12.5 0.1 2.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Prefoldin_3 PF13758.1 EPY52727.1 - 0.0071 16.0 2.8 0.067 12.9 0.2 3.2 2 1 1 3 3 3 1 Prefoldin subunit Reo_sigmaC PF04582.7 EPY52727.1 - 0.11 11.7 1.6 0.46 9.6 0.9 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein EF-hand_6 PF13405.1 EPY52727.1 - 0.23 11.4 1.1 3.7 7.6 0.8 2.8 2 0 0 2 2 2 0 EF-hand domain APG6 PF04111.7 EPY52727.1 - 0.35 9.8 13.3 0.64 8.9 9.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EPY52727.1 - 1.7 8.5 21.2 0.3 10.9 7.9 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seipin PF06775.9 EPY52728.1 - 5.5e-51 172.9 1.5 7.1e-51 172.5 1.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Methyltransf_16 PF10294.4 EPY52729.1 - 1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EPY52729.1 - 4.6e-06 25.9 0.0 8.2e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EPY52729.1 - 0.00015 22.3 0.0 0.00046 20.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPY52729.1 - 0.00036 19.9 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EPY52729.1 - 0.0059 16.2 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EPY52729.1 - 0.0073 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY52729.1 - 0.025 14.3 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-CCCH PF00642.19 EPY52730.1 - 1.2e-06 27.9 12.0 0.002 17.7 2.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPY52730.1 - 2.5 8.2 17.6 1 9.4 3.2 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Xpo1 PF08389.7 EPY52731.1 - 1.9e-16 60.3 0.3 1.9e-16 60.3 0.2 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBR PF01485.16 EPY52732.1 - 2e-21 75.6 45.9 3.6e-11 42.7 3.3 4.7 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EPY52732.1 - 4.3e-05 23.0 3.9 4.3e-05 23.0 2.7 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY52732.1 - 0.0036 17.3 6.2 0.0036 17.3 4.3 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY52732.1 - 0.005 16.6 4.2 0.005 16.6 2.9 3.8 2 1 1 3 3 3 1 Ring finger domain Glyco_transf_20 PF00982.16 EPY52733.1 - 2.4e-200 666.0 0.0 2.8e-200 665.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EPY52733.1 - 0.0037 16.6 0.2 1.1 8.6 0.0 3.2 3 1 0 3 3 3 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPY52733.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 AAA PF00004.24 EPY52734.1 - 3.3e-39 134.0 0.2 1.9e-38 131.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPY52734.1 - 2.5e-08 33.6 0.0 7.7e-06 25.7 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EPY52734.1 - 4.6e-06 26.8 0.1 0.00012 22.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPY52734.1 - 2.2e-05 23.6 0.0 4.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPY52734.1 - 0.00011 22.2 0.7 0.001 19.0 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EPY52734.1 - 0.00024 20.8 0.0 0.001 18.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EPY52734.1 - 0.00059 18.6 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EPY52734.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPY52734.1 - 0.0017 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 EPY52734.1 - 0.0027 17.2 0.7 0.0092 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPY52734.1 - 0.0033 17.3 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPY52734.1 - 0.0033 17.1 0.2 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EPY52734.1 - 0.0034 16.5 0.1 0.0071 15.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EPY52734.1 - 0.0035 17.2 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EPY52734.1 - 0.0047 16.3 0.1 0.086 12.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EPY52734.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EPY52734.1 - 0.021 13.7 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPY52734.1 - 0.024 15.4 0.0 0.082 13.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EPY52734.1 - 0.046 13.1 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase NACHT PF05729.7 EPY52734.1 - 0.057 13.0 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EPY52734.1 - 0.062 13.6 0.0 0.26 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPY52734.1 - 0.077 12.9 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EPY52734.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EPY52734.1 - 0.094 12.4 0.0 0.42 10.2 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 EPY52734.1 - 0.11 11.9 0.0 0.29 10.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EPY52734.1 - 0.16 11.0 0.1 2 7.4 0.0 2.3 1 1 1 2 2 2 0 KaiC RRM_1 PF00076.17 EPY52735.1 - 1.3e-55 184.9 0.0 9.8e-19 66.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52735.1 - 3.4e-42 142.2 0.0 2.7e-14 52.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52735.1 - 2.1e-28 97.8 0.0 5.8e-10 38.8 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPY52735.1 - 5.2e-05 22.9 0.2 0.084 12.6 0.0 3.1 3 0 0 3 3 3 2 Limkain b1 UCH PF00443.24 EPY52736.1 - 1e-48 165.8 6.1 1e-48 165.8 4.3 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EPY52736.1 - 5.3e-44 147.4 6.7 9.4e-19 66.5 0.1 4.8 5 0 0 5 5 5 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EPY52736.1 - 3.7e-15 56.1 6.9 2.4e-06 27.2 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RRM_6 PF14259.1 EPY52736.1 - 0.11 12.5 0.1 4.3 7.3 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2370 PF10176.4 EPY52737.1 - 1.3e-55 188.3 4.0 1e-53 182.1 0.3 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2370) DUF4112 PF13430.1 EPY52737.1 - 0.027 14.3 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) TBCC PF07986.7 EPY52738.1 - 4.3e-24 84.2 3.7 7.7e-24 83.4 2.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C MFS_1 PF07690.11 EPY52739.1 - 2.8e-15 55.9 30.4 2.8e-15 55.9 21.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0542 PF15086.1 EPY52739.1 - 0.14 11.8 1.1 0.49 10.1 0.1 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 UPF0370 PF13980.1 EPY52739.1 - 0.48 10.2 5.6 0.68 9.7 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) Mito_carr PF00153.22 EPY52740.1 - 1.7e-71 236.0 1.6 8.4e-26 89.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S7 PF00177.16 EPY52741.1 - 1.4e-39 135.0 0.6 1.7e-39 134.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SHD1 PF03983.7 EPY52742.1 - 8e-32 108.7 0.2 1.5e-31 107.8 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EPY52742.1 - 8.1e-26 89.3 9.6 1.1e-10 40.9 0.0 4.6 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.23 EPY52742.1 - 7.1e-24 82.9 2.2 4.8e-11 41.8 0.0 4.8 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.12 EPY52742.1 - 3.8e-17 61.5 0.0 4.4e-05 22.8 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EPY52742.1 - 7.2e-07 29.1 53.7 6.3e-06 26.1 15.9 6.6 2 1 3 5 5 5 2 Domain of unknown function (DUF1720) DUF962 PF06127.6 EPY52743.1 - 5.8e-25 87.0 2.7 1e-24 86.1 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Acetyltransf_1 PF00583.19 EPY52743.1 - 3e-15 56.0 0.0 5.2e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY52743.1 - 8.8e-11 41.8 0.1 2e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPY52743.1 - 6.1e-06 26.4 0.0 8.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPY52743.1 - 9.5e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY52743.1 - 0.0013 18.5 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EPY52743.1 - 0.041 13.1 0.1 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.5 EPY52743.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein AstA PF04958.7 EPY52743.1 - 0.13 10.6 0.0 0.24 9.7 0.0 1.3 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit CM_2 PF01817.16 EPY52744.1 - 5.7e-10 39.1 0.1 6.1e-08 32.6 0.0 3.2 3 1 0 3 3 3 1 Chorismate mutase type II DUF2778 PF10908.3 EPY52744.1 - 0.14 12.4 0.0 0.82 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) RRM_1 PF00076.17 EPY52746.1 - 1.4e-21 75.8 0.2 7.4e-16 57.5 0.0 3.9 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52746.1 - 2.5e-16 59.3 0.1 1.3e-10 41.1 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52746.1 - 2.3e-12 46.5 0.1 2.5e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EPY52746.1 - 0.0068 16.1 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EPY52746.1 - 0.077 12.7 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CDC45 PF02724.9 EPY52746.1 - 0.17 9.8 12.9 0.23 9.4 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein V_ATPase_I PF01496.14 EPY52747.1 - 2.2e-288 958.3 7.1 2.5e-288 958.1 4.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SARS_lipid_bind PF09399.5 EPY52747.1 - 0.034 14.1 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 SARS lipid binding protein Med4 PF10018.4 EPY52748.1 - 0.21 10.9 3.5 0.096 12.0 0.4 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 PH_10 PF15411.1 EPY52749.1 - 6.7e-37 126.2 0.0 1.3e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EPY52749.1 - 7.7e-37 126.8 5.3 7.7e-37 126.8 3.7 1.7 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 EPY52749.1 - 3.8e-29 100.5 0.0 1e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 EPY52749.1 - 6.6e-19 67.3 0.1 1.7e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EPY52749.1 - 0.011 15.9 0.1 0.024 14.8 0.1 1.6 1 0 0 1 1 1 0 PH domain Ribosomal_S7 PF00177.16 EPY52750.1 - 2.4e-34 118.0 1.4 3.3e-34 117.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e BSD PF03909.12 EPY52751.1 - 2.7e-25 87.8 1.7 8.9e-12 44.5 0.0 3.2 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EPY52751.1 - 6.3e-12 44.9 0.0 1.6e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain FAM86 PF14904.1 EPY52751.1 - 0.12 12.1 0.6 5.1 6.8 0.0 2.9 3 1 0 3 3 3 0 Family of unknown function ING PF12998.2 EPY52752.1 - 2.4e-05 24.5 1.0 3.7e-05 23.9 0.7 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding IL2 PF00715.12 EPY52752.1 - 0.1 12.3 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Interleukin 2 DUF3020 PF11223.3 EPY52752.1 - 0.17 12.3 3.8 0.29 11.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) Cep57_MT_bd PF06657.8 EPY52752.1 - 0.4 10.6 3.0 1.7 8.6 0.2 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ING PF12998.2 EPY52753.1 - 4.4e-05 23.7 1.0 4.4e-05 23.7 0.7 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF3020 PF11223.3 EPY52753.1 - 0.03 14.7 0.3 0.051 13.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) Cep57_MT_bd PF06657.8 EPY52753.1 - 0.49 10.3 3.0 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 BRAP2 PF07576.7 EPY52754.1 - 1e-29 102.3 0.3 7e-29 99.6 0.0 2.4 3 0 0 3 3 3 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EPY52754.1 - 1.4e-16 60.3 19.3 7.3e-16 58.0 13.4 2.2 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EPY52754.1 - 7.7e-09 35.2 9.9 7.7e-09 35.2 6.8 2.5 2 1 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 EPY52754.1 - 9.7e-05 22.3 5.0 9.7e-05 22.3 3.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPY52754.1 - 0.00018 21.4 9.7 0.00018 21.4 6.7 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY52754.1 - 0.00034 20.2 10.5 0.00054 19.5 6.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.10 EPY52754.1 - 0.0085 15.5 6.5 0.99 8.9 0.4 2.9 2 0 0 2 2 2 2 Septum formation initiator CENP-Q PF13094.1 EPY52754.1 - 0.051 13.5 12.5 0.1 12.6 8.6 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EPY52754.1 - 0.44 10.1 18.3 19 4.7 12.7 2.3 1 1 0 1 1 1 0 IncA protein zf-RING_UBOX PF13445.1 EPY52754.1 - 2.5 7.8 11.7 0.3 10.8 2.1 2.7 2 0 0 2 2 2 0 RING-type zinc-finger SlyX PF04102.7 EPY52754.1 - 7.2 7.0 10.4 14 6.0 0.4 3.4 1 1 2 3 3 3 0 SlyX Methyltransf_PK PF05891.7 EPY52755.1 - 3.5e-86 288.0 0.0 3.9e-86 287.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EPY52755.1 - 1.8e-05 25.2 0.0 2.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY52755.1 - 5.3e-05 23.6 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY52755.1 - 0.00018 21.8 0.0 0.00038 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Flavodoxin_5 PF12724.2 EPY52755.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain IF4E PF01652.13 EPY52756.1 - 5.6e-54 182.1 0.1 7e-54 181.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TFIIB PF00382.14 EPY52757.1 - 1.7e-44 149.4 0.2 2.3e-24 84.9 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EPY52757.1 - 2.6e-13 49.0 1.7 4.1e-13 48.4 1.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_27 PF13463.1 EPY52757.1 - 0.037 14.3 0.0 19 5.7 0.0 3.1 2 1 0 2 2 2 0 Winged helix DNA-binding domain HTH_23 PF13384.1 EPY52757.1 - 0.04 13.5 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain Cyclin_N PF00134.18 EPY52757.1 - 0.041 13.4 0.1 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 Cyclin, N-terminal domain Sigma70_r4_2 PF08281.7 EPY52757.1 - 0.058 12.8 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.15 EPY52757.1 - 0.1 12.2 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family TrmB PF01978.14 EPY52757.1 - 0.13 11.9 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MerR PF00376.18 EPY52757.1 - 0.15 11.5 0.1 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein Ligase_CoA PF00549.14 EPY52758.1 - 2.2e-27 95.5 0.1 4.3e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EPY52758.1 - 8.1e-25 87.1 4.6 1.8e-24 86.0 0.3 2.6 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.1 EPY52758.1 - 2e-10 40.4 0.0 3.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EPY52758.1 - 0.0093 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Ead_Ea22 PF13935.1 EPY52759.1 - 0.061 13.6 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein zf-C2H2 PF00096.21 EPY52760.1 - 0.00022 21.3 1.3 0.00022 21.3 0.9 3.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPY52760.1 - 0.00087 19.1 0.3 0.00087 19.1 0.2 2.4 2 1 0 2 2 2 1 C2H2-type zinc finger BAT2_N PF07001.6 EPY52760.1 - 0.0087 16.4 4.9 0.0087 16.4 3.4 3.1 3 0 0 3 3 3 1 BAT2 N-terminus DUF3505 PF12013.3 EPY52760.1 - 0.044 14.0 3.1 5.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 EPY52760.1 - 0.52 10.5 4.0 0.53 10.4 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NAD_kinase PF01513.16 EPY52761.1 - 4.1e-84 281.7 0.0 5.5e-84 281.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF2117 PF09890.4 EPY52761.1 - 0.21 10.7 0.6 0.42 9.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2117) HEAT PF02985.17 EPY52762.1 - 3e-17 61.0 12.3 0.00072 19.4 0.0 9.1 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EPY52762.1 - 1.8e-15 56.8 8.8 2.5e-06 27.7 0.0 8.4 9 1 1 10 10 10 3 HEAT-like repeat IBN_N PF03810.14 EPY52762.1 - 5.6e-14 51.8 1.6 2.2e-13 49.8 0.9 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EPY52762.1 - 9.3e-12 45.0 10.5 8.2e-07 29.2 0.0 6.1 3 1 3 6 6 6 2 HEAT repeats Arm PF00514.18 EPY52762.1 - 7.1e-05 22.4 6.3 1.4 8.9 0.1 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EPY52762.1 - 0.00047 19.5 0.7 0.84 8.9 0.1 3.9 2 1 0 3 3 3 1 CLASP N terminal TIP120 PF08623.5 EPY52762.1 - 0.024 14.2 0.4 1.1 8.8 0.0 3.7 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) Pkinase PF00069.20 EPY52763.1 - 0.034 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain MFS_1 PF07690.11 EPY52764.1 - 3e-30 105.1 26.1 3e-30 105.1 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY52764.1 - 1.7e-11 43.3 11.5 1.7e-11 43.3 8.0 2.3 1 1 0 2 2 2 1 Sugar (and other) transporter Corona_S2 PF01601.11 EPY52764.1 - 0.036 12.1 0.5 0.056 11.5 0.4 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein TRAM_LAG1_CLN8 PF03798.11 EPY52765.1 - 4.5e-36 124.2 17.6 6.5e-36 123.7 12.2 1.2 1 0 0 1 1 1 1 TLC domain Ni_hydr_CYTB PF01292.15 EPY52765.1 - 0.033 13.5 4.4 0.082 12.2 1.1 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 vATP-synt_AC39 PF01992.11 EPY52766.1 - 7.5e-98 327.7 0.6 8.7e-98 327.5 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TPR_11 PF13414.1 EPY52767.1 - 1.7e-14 53.2 1.3 1.8e-12 46.7 0.4 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EPY52767.1 - 5.9e-09 35.1 5.7 0.011 15.3 1.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52767.1 - 8.8e-09 35.5 2.0 1.8e-06 28.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52767.1 - 1.3e-05 24.7 7.2 0.027 14.3 1.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52767.1 - 0.00044 20.1 3.8 0.41 10.6 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52767.1 - 0.00049 20.6 2.2 0.099 13.3 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3808 PF10300.4 EPY52767.1 - 0.0028 16.3 1.1 0.0038 15.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Apc3 PF12895.2 EPY52767.1 - 0.0033 17.5 4.2 0.01 15.9 2.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EPY52767.1 - 0.0047 16.5 3.2 2.8 7.9 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY52767.1 - 0.0057 16.3 1.3 0.46 10.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52767.1 - 0.16 12.7 2.4 13 6.7 0.1 3.3 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPY52767.1 - 0.25 11.3 1.6 5.6 7.0 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY52767.1 - 1.1 9.8 5.6 20 5.9 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat FAD_binding_2 PF00890.19 EPY52768.1 - 1.5e-73 248.0 0.0 1.8e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPY52768.1 - 1e-06 27.8 0.0 0.0004 19.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPY52768.1 - 3.7e-06 26.9 0.0 0.00052 19.9 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPY52768.1 - 5.2e-06 26.4 0.8 1.7e-05 24.7 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPY52768.1 - 1.2e-05 23.9 4.3 0.00092 17.7 0.2 2.6 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.1 EPY52768.1 - 8.5e-05 22.7 0.0 0.00019 21.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPY52768.1 - 0.001 17.9 2.2 0.0068 15.3 0.2 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EPY52768.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPY52768.1 - 0.0033 16.5 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPY52768.1 - 0.011 14.8 0.6 0.11 11.6 0.1 2.2 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 EPY52768.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Vps8 PF12816.2 EPY52769.1 - 2.5e-34 118.2 4.1 4.9e-34 117.2 2.3 2.0 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 WD40 PF00400.27 EPY52769.1 - 0.0052 16.6 1.8 0.057 13.3 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat NTR2 PF15458.1 EPY52771.1 - 2.7e-23 82.5 16.8 3.4e-23 82.1 11.7 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 RRM_1 PF00076.17 EPY52772.1 - 2.7e-37 126.2 0.0 2.9e-16 58.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52772.1 - 1.7e-21 75.8 0.0 7.5e-09 35.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52772.1 - 6.4e-18 64.5 0.0 3.7e-06 26.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY52772.1 - 1.8e-05 24.3 0.0 0.0011 18.6 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPY52772.1 - 0.00069 19.4 0.0 0.016 15.0 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif Laminin_G_1 PF00054.18 EPY52772.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain SNF2_N PF00176.18 EPY52773.1 - 6.2e-74 248.4 1.5 9.7e-74 247.8 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY52773.1 - 3.8e-12 45.9 0.1 1.2e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EPY52773.1 - 7.2e-08 31.9 12.8 1.4e-07 31.0 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EPY52773.1 - 2.8e-06 26.9 0.1 1.7e-05 24.3 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 EPY52773.1 - 1.9e-05 24.6 16.3 4.4e-05 23.4 11.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY52773.1 - 2.4e-05 24.0 15.6 6.1e-05 22.7 10.8 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPY52773.1 - 0.0012 18.5 13.7 0.0024 17.5 9.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPY52773.1 - 0.006 16.2 16.8 0.014 15.0 11.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPY52773.1 - 0.25 11.0 11.0 0.91 9.3 7.6 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPY52773.1 - 0.38 10.6 17.7 0.87 9.5 12.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPY52773.1 - 0.61 10.2 7.7 1.6 8.9 5.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 EPY52773.1 - 2.1 7.9 12.0 6 6.4 8.3 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger 14-3-3 PF00244.15 EPY52774.1 - 8.4e-115 381.7 4.8 9.9e-115 381.5 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EPY52774.1 - 8e-05 22.2 3.8 0.047 13.2 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF837) Latarcin PF10279.4 EPY52774.1 - 0.04 14.1 2.7 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 Latarcin precursor TPR_12 PF13424.1 EPY52774.1 - 0.052 13.4 0.2 11 6.0 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat CorA PF01544.13 EPY52775.1 - 9.2e-51 172.5 0.1 1.6e-50 171.7 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Metallophos PF00149.23 EPY52776.1 - 1.7e-12 47.1 4.7 1.7e-12 47.1 3.3 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Cut12 PF11500.3 EPY52776.1 - 0.093 12.4 0.2 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Prenyltrans PF00432.16 EPY52777.1 - 9.5e-35 117.8 21.6 2.2e-10 39.9 0.7 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPY52777.1 - 2e-23 82.9 0.0 1.2e-15 57.8 0.0 3.8 2 2 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPY52777.1 - 4.9e-09 36.1 0.0 0.00021 21.2 0.0 3.2 2 1 1 3 3 3 2 Prenyltransferase-like BRO1 PF03097.13 EPY52778.1 - 5.4e-94 315.0 2.1 5.4e-94 315.0 1.5 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPY52778.1 - 1.1e-42 146.0 18.5 1.1e-42 146.0 12.8 2.2 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV Phage_lysis PF03245.8 EPY52778.1 - 0.017 15.0 1.3 0.057 13.4 0.9 1.9 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein TPR_7 PF13176.1 EPY52778.1 - 1.4 8.8 5.2 18 5.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S24e PF01282.14 EPY52779.1 - 4.2e-34 116.1 0.0 6.4e-34 115.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Use1 PF09753.4 EPY52780.1 - 1.1e-12 47.9 7.7 1.3e-12 47.7 5.3 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2828 PF11443.3 EPY52780.1 - 0.014 13.6 3.0 0.016 13.4 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) COMPASS-Shg1 PF05205.7 EPY52780.1 - 0.11 12.7 4.3 0.23 11.7 3.0 1.5 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 FYVE PF01363.16 EPY52781.1 - 5.6e-24 83.8 24.0 1.3e-15 56.9 7.2 3.2 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 EPY52781.1 - 0.00042 19.8 0.5 0.0016 17.9 0.4 2.0 1 0 0 1 1 1 1 Rabenosyn Rab binding domain IBR PF01485.16 EPY52781.1 - 0.0043 16.8 1.0 0.0043 16.8 0.7 4.1 4 1 1 5 5 4 2 IBR domain TerY-C PF15616.1 EPY52781.1 - 0.0081 16.0 6.4 0.021 14.7 0.4 3.4 3 0 0 3 3 3 1 TerY-C metal binding domain zf-AN1 PF01428.11 EPY52781.1 - 0.0082 16.0 6.8 0.0082 16.0 4.7 4.3 4 1 1 5 5 4 1 AN1-like Zinc finger zinc-ribbons_6 PF07191.7 EPY52781.1 - 0.28 11.0 17.9 8 6.3 1.0 4.6 3 1 0 3 3 3 0 zinc-ribbons zf-Di19 PF05605.7 EPY52781.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.6 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EPY52781.1 - 0.96 9.9 0.0 0.96 9.9 0.0 5.3 4 1 1 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPY52781.1 - 1.5 9.2 0.0 1.5 9.2 0.0 5.5 5 1 1 6 6 6 0 Zinc finger, C2H2 type OrfB_Zn_ribbon PF07282.6 EPY52781.1 - 1.8 8.2 16.2 0.053 13.1 1.5 3.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain AAA_23 PF13476.1 EPY52781.1 - 7 6.9 15.8 47 4.2 11.0 2.3 1 1 0 1 1 1 0 AAA domain Sec62 PF03839.11 EPY52782.1 - 3.3e-68 229.4 1.1 4.7e-68 228.9 0.8 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 DUF3309 PF11752.3 EPY52782.1 - 0.77 9.5 6.1 1.5 8.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) SWIRM PF04433.12 EPY52783.1 - 1.9e-30 104.8 0.7 4.6e-30 103.5 0.1 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EPY52783.1 - 1.3e-07 31.5 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY52783.1 - 0.0007 19.6 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Zn_ribbon_2 PF12674.2 EPY52783.1 - 0.14 12.5 2.0 0.25 11.6 0.2 2.3 2 0 0 2 2 2 0 Putative zinc ribbon domain SKN1 PF03935.10 EPY52784.1 - 5.8e-210 697.7 4.5 6.7e-210 697.4 3.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cullin PF00888.17 EPY52785.1 - 5.1e-175 583.3 17.1 6.7e-175 582.9 11.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPY52785.1 - 2.1e-26 91.5 5.7 3.5e-26 90.8 2.8 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF2096 PF09869.4 EPY52785.1 - 0.47 10.3 6.6 0.098 12.5 0.4 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2096) DUF4243 PF14027.1 EPY52786.1 - 0.13 11.6 7.0 0.031 13.7 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4243) GlutR_dimer PF00745.15 EPY52786.1 - 0.15 12.0 7.7 0.15 12.0 4.0 2.0 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Pox_G5 PF04599.7 EPY52786.1 - 0.72 8.4 2.9 1.1 7.9 2.0 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein Selenoprotein_S PF06936.6 EPY52786.1 - 3.7 7.0 9.1 9.9 5.6 6.3 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) DEAD PF00270.24 EPY52787.1 - 1.9e-34 118.6 0.1 3.1e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY52787.1 - 6.9e-27 93.1 0.0 4.6e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY52787.1 - 6.4e-07 29.3 0.1 1.8e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EPY52787.1 - 0.028 13.4 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Mtc PF03820.12 EPY52788.1 - 3.9e-92 308.1 0.1 4.7e-92 307.9 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF4244 PF14029.1 EPY52788.1 - 0.079 12.0 0.4 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) CPSF73-100_C PF11718.3 EPY52789.1 - 4.6e-63 212.4 2.3 7.3e-63 211.7 1.6 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EPY52789.1 - 4.8e-34 117.0 0.0 4.6e-33 113.8 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EPY52789.1 - 2.4e-14 53.4 1.3 4.8e-14 52.4 0.9 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPY52789.1 - 2e-12 47.0 0.9 3.7e-12 46.2 0.2 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EPY52789.1 - 6.3e-08 32.3 0.2 1.7e-07 30.8 0.1 1.9 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EPY52789.1 - 5.5e-07 29.4 0.2 2.1e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RRM_3 PF08777.6 EPY52790.1 - 3.3e-05 23.6 0.0 0.00025 20.8 0.0 2.4 1 1 0 1 1 1 1 RNA binding motif CRIC_ras_sig PF10534.4 EPY52790.1 - 0.071 13.1 0.1 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras Tcf25 PF04910.9 EPY52791.1 - 1.7e-80 270.6 0.5 3.2e-80 269.7 0.3 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_11 PF13414.1 EPY52792.1 - 3.7e-26 90.5 7.7 2.4e-21 75.1 0.5 2.9 2 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EPY52792.1 - 1.5e-19 68.6 7.1 4.2e-06 26.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52792.1 - 2.7e-17 61.2 7.7 7.8e-05 22.2 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52792.1 - 3.3e-13 48.7 3.7 1.7e-07 30.8 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPY52792.1 - 1e-11 43.7 4.0 0.00055 19.5 0.0 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52792.1 - 1.7e-11 43.7 3.9 0.0008 19.8 0.3 4.5 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52792.1 - 3.7e-10 40.2 9.4 1.1e-05 25.9 3.4 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52792.1 - 2.2e-08 34.3 5.6 7.4e-05 23.0 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52792.1 - 4.1e-08 33.0 6.4 1.6e-06 27.9 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY52792.1 - 5.7e-08 31.9 7.4 0.02 14.6 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPY52792.1 - 3.3e-06 26.8 0.5 0.00053 19.7 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EPY52792.1 - 5e-06 26.5 0.2 1.4e-05 25.1 0.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EPY52792.1 - 0.00037 20.8 1.6 0.012 15.8 0.1 2.7 3 0 0 3 3 3 1 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.1 EPY52792.1 - 0.00095 19.4 2.5 0.0017 18.6 0.7 2.1 1 1 1 2 2 2 1 Alkyl sulfatase dimerisation NARP1 PF12569.3 EPY52792.1 - 0.011 14.5 1.2 0.12 11.0 0.2 2.1 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 EPY52792.1 - 0.016 15.6 0.7 7 7.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 EPY52792.1 - 0.042 12.9 2.0 0.29 10.1 0.6 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPY52792.1 - 0.071 13.2 1.7 1 9.5 0.0 3.1 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY52792.1 - 0.19 12.2 7.1 29 5.4 0.2 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Noc2 PF03715.8 EPY52794.1 - 1.2e-104 349.3 3.7 1.2e-104 349.3 2.5 2.3 3 0 0 3 3 3 1 Noc2p family DUF999 PF06198.6 EPY52795.1 - 1e-06 28.6 5.3 3.5e-06 26.8 3.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF999) DUF3533 PF12051.3 EPY52795.1 - 6 5.4 13.5 8 5.0 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Serinc PF03348.10 EPY52796.1 - 2.1e-128 428.6 31.1 3.2e-128 428.1 21.6 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) MAP65_ASE1 PF03999.7 EPY52798.1 - 1e-112 377.7 19.4 1.4e-112 377.3 13.4 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) CK2S PF15011.1 EPY52798.1 - 0.01 15.5 1.0 0.01 15.5 0.7 2.4 2 1 0 2 2 2 0 Casein Kinase 2 substrate Syntaxin PF00804.20 EPY52798.1 - 1.8 8.7 6.0 2 8.6 0.1 3.4 2 1 1 3 3 3 0 Syntaxin Ras PF00071.17 EPY52799.1 - 5e-54 182.0 0.1 5.9e-54 181.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY52799.1 - 5.9e-21 75.1 0.1 9e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY52799.1 - 1.9e-13 49.9 0.0 2.2e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPY52799.1 - 1.9e-08 33.9 0.0 3.4e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPY52799.1 - 2.7e-06 27.3 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPY52799.1 - 8.2e-06 25.1 0.1 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPY52799.1 - 0.00038 20.5 0.0 0.0014 18.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EPY52799.1 - 0.00039 19.6 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EPY52799.1 - 0.0022 17.2 0.1 0.0057 15.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EPY52799.1 - 0.0026 17.4 0.1 0.0071 16.0 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EPY52799.1 - 0.0045 16.7 0.1 0.025 14.3 0.0 1.9 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EPY52799.1 - 0.0046 16.4 0.1 0.0083 15.6 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain Septin PF00735.13 EPY52799.1 - 0.0047 15.9 0.2 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 EPY52799.1 - 0.008 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY52799.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 EPY52799.1 - 0.014 14.6 0.1 0.56 9.4 0.1 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 EPY52799.1 - 0.017 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.12 EPY52799.1 - 0.035 13.6 0.1 1.7 8.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 EPY52799.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EPY52799.1 - 0.051 13.0 0.1 0.11 11.9 0.1 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EPY52799.1 - 0.062 12.7 0.1 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPY52799.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPY52799.1 - 0.071 13.2 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_5 PF07728.9 EPY52799.1 - 0.076 12.7 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EPY52799.1 - 0.076 13.3 0.9 0.16 12.2 0.6 1.8 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EPY52799.1 - 0.084 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 NTPase PRK PF00485.13 EPY52799.1 - 0.11 11.9 0.1 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family tRNA-synt_1c PF00749.16 EPY52800.1 - 3.2e-88 295.4 0.0 4.2e-46 157.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain YfiO PF13525.1 EPY52800.1 - 0.069 12.6 0.1 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Outer membrane lipoprotein ALO PF04030.9 EPY52801.1 - 4.6e-74 249.2 2.4 6.3e-74 248.8 1.7 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EPY52801.1 - 7.1e-30 103.2 0.2 1.4e-29 102.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Arv1 PF04161.8 EPY52804.1 - 2e-45 155.2 9.8 2e-45 155.2 6.8 2.0 2 1 0 2 2 2 1 Arv1-like family TF_Zn_Ribbon PF08271.7 EPY52804.1 - 0.15 11.3 2.0 1.3 8.4 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding adh_short_C2 PF13561.1 EPY52805.1 - 4.3e-17 62.6 0.0 4.8e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPY52805.1 - 1.9e-06 27.9 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fer2_3 PF13085.1 EPY52806.1 - 5.4e-33 113.1 0.1 8.9e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EPY52806.1 - 1.2e-10 41.5 6.8 1.2e-10 41.5 4.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EPY52806.1 - 1.6e-08 34.4 5.6 1.6e-08 34.4 3.9 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EPY52806.1 - 9.9e-05 22.6 3.8 9.9e-05 22.6 2.6 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EPY52806.1 - 0.00017 21.3 5.7 0.00017 21.3 4.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EPY52806.1 - 0.004 16.8 6.2 0.0043 16.7 0.6 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EPY52806.1 - 0.0057 17.0 6.8 0.0057 17.0 4.7 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 EPY52806.1 - 0.071 13.5 0.9 0.071 13.5 0.6 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding AFT PF08731.6 EPY52806.1 - 0.12 12.6 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 Transcription factor AFT Fer4_9 PF13187.1 EPY52806.1 - 0.12 12.6 14.3 5 7.4 0.0 3.2 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EPY52806.1 - 5.4 7.6 9.2 1.6 9.3 0.2 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain RRM_1 PF00076.17 EPY52807.1 - 3.5e-39 132.2 0.0 3.6e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52807.1 - 6.3e-30 102.9 0.0 1.9e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52807.1 - 3.1e-14 52.5 0.0 4.9e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY52807.1 - 0.015 15.0 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arb1 PF09692.5 EPY52808.1 - 1.2e-83 281.2 0.6 1.4e-83 280.9 0.4 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF4078 PF13300.1 EPY52809.1 - 1.9e-18 66.3 5.0 1.9e-18 66.3 3.5 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4078) Pkinase PF00069.20 EPY52810.1 - 8.8e-61 205.3 0.0 1.4e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52810.1 - 1.7e-35 122.3 0.0 2.9e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY52810.1 - 4.5e-08 32.4 0.0 1.1e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPY52810.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPY52810.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EPY52810.1 - 0.028 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.17 EPY52811.1 - 3.1e-07 29.9 1.0 0.06 13.4 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EPY52811.1 - 1.8e-06 28.1 0.0 0.00039 20.6 0.0 4.4 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EPY52811.1 - 0.0015 18.9 0.4 5 7.7 0.0 4.0 4 0 0 4 4 4 2 HEAT-like repeat DUF2435 PF10363.4 EPY52811.1 - 0.0046 16.8 1.2 13 5.7 0.0 4.6 2 1 2 4 4 4 2 Protein of unknown function (DUF2435) Ras PF00071.17 EPY52812.1 - 9.7e-53 177.8 0.0 1.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY52812.1 - 8.7e-16 58.4 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY52812.1 - 4.7e-08 32.4 0.0 6.7e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family HSP70 PF00012.15 EPY52813.1 - 6.2e-159 529.7 0.0 6.2e-159 529.7 0.0 1.6 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EPY52813.1 - 3.8e-11 42.1 0.0 1.2e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EPY52813.1 - 0.012 15.3 4.9 0.81 9.5 0.2 3.8 3 2 0 3 3 3 0 Cell division protein FtsA FHA PF00498.21 EPY52814.1 - 1.2e-05 25.2 0.2 2.6e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain V-SNARE_C PF12352.3 EPY52815.1 - 2e-16 59.8 1.0 3.6e-16 58.9 0.7 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EPY52815.1 - 4.4e-07 29.5 1.1 1e-06 28.3 0.0 2.1 3 0 0 3 3 3 1 Sec20 DUF1649 PF07855.7 EPY52815.1 - 0.063 12.9 0.3 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1649) TF_AP-2 PF03299.9 EPY52815.1 - 0.068 12.7 0.5 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Transcription factor AP-2 Retrotrans_gag PF03732.12 EPY52815.1 - 0.091 12.8 0.1 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein COG2 PF06148.6 EPY52815.1 - 1.9 8.3 4.9 4.1 7.2 2.1 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 EPY52815.1 - 4.1 7.4 6.7 19 5.3 0.5 2.8 2 1 1 3 3 3 0 Cortexillin I, coiled coil Peptidase_M48 PF01435.13 EPY52816.1 - 3.2e-35 121.7 0.0 4.8e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Tmemb_14 PF03647.8 EPY52817.1 - 4.2e-21 75.1 8.5 4.7e-21 74.9 5.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C VPEP PF07589.6 EPY52817.1 - 9.1 6.3 10.9 20 5.2 0.3 3.7 4 0 0 4 4 4 0 PEP-CTERM motif Phytochelatin PF05023.9 EPY52818.1 - 1.7e-80 268.9 0.0 2.6e-80 268.3 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Pox_F11 PF04943.7 EPY52818.1 - 0.0033 16.3 0.1 0.0049 15.7 0.1 1.2 1 0 0 1 1 1 1 Poxvirus F11 protein YlbD_coat PF14071.1 EPY52818.1 - 0.0074 16.3 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Putative coat protein NADH_u_ox_C PF12853.2 EPY52818.1 - 0.026 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Aa_trans PF01490.13 EPY52819.1 - 1.7e-88 296.8 39.8 2.1e-88 296.5 27.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1640 PF07798.6 EPY52820.1 - 2e-29 102.8 7.9 2.5e-29 102.5 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ETC_C1_NDUFA4 PF04800.7 EPY52820.1 - 0.073 12.9 0.4 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 ETC complex I subunit conserved region Arginase PF00491.16 EPY52821.1 - 3.6e-71 239.6 0.0 4.2e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family Peptidase_M48 PF01435.13 EPY52822.1 - 8.4e-55 185.7 0.0 1.1e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.4 EPY52822.1 - 0.18 11.4 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 SprT-like family MDM31_MDM32 PF08118.6 EPY52823.1 - 6.3e-135 450.4 4.4 1.4e-134 449.2 3.1 1.4 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HCNGP PF07818.8 EPY52824.1 - 1.8e-23 82.3 0.1 2.6e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein Peptidase_M16_C PF05193.16 EPY52825.1 - 2e-19 69.9 0.0 3.4e-12 46.3 0.0 3.2 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPY52825.1 - 1.6e-13 50.6 0.0 3.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FliM PF02154.10 EPY52825.1 - 0.0089 15.7 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 Flagellar motor switch protein FliM Glyco_transf_9 PF01075.12 EPY52825.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) ORC3_N PF07034.6 EPY52826.1 - 9e-09 34.7 5.0 2.3e-06 26.8 0.1 2.9 3 0 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus TFIIH_BTF_p62_N PF08567.6 EPY52826.1 - 0.12 12.0 0.3 0.31 10.7 0.2 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain zf-C2H2_4 PF13894.1 EPY52827.1 - 8.1e-09 35.2 13.7 0.0006 19.9 4.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPY52827.1 - 2e-08 34.0 19.4 0.00011 22.2 4.9 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPY52827.1 - 0.0015 18.6 12.9 0.018 15.1 2.7 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPY52827.1 - 0.0029 17.7 7.1 0.055 13.7 1.3 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EPY52827.1 - 0.019 15.2 4.3 0.019 15.2 3.0 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPY52827.1 - 0.025 14.4 9.6 0.064 13.1 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBR PF02207.15 EPY52827.1 - 0.045 13.4 2.9 0.081 12.6 2.0 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF629 PF04780.7 EPY52827.1 - 0.18 10.2 2.2 0.26 9.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-BED PF02892.10 EPY52827.1 - 0.61 9.8 8.0 8.9 6.1 5.6 2.3 1 1 0 1 1 1 0 BED zinc finger zf-HC5HC2H_2 PF13832.1 EPY52828.1 - 4.7e-17 61.9 19.2 1.3e-15 57.3 0.5 4.4 4 0 0 4 4 4 3 PHD-zinc-finger like domain BAH PF01426.13 EPY52828.1 - 1.6e-13 50.4 0.1 3.5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.1 EPY52828.1 - 2e-10 40.6 20.8 6.3e-10 39.0 0.0 4.2 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.24 EPY52828.1 - 3.7e-10 39.3 21.2 4.2e-08 32.7 8.0 6.6 6 1 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EPY52828.1 - 0.0046 16.2 0.2 0.0046 16.2 0.2 5.8 6 0 0 6 6 6 2 PHD-finger Prok-RING_1 PF14446.1 EPY52828.1 - 0.012 15.3 1.4 0.012 15.3 1.0 4.4 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 Pkinase PF00069.20 EPY52829.1 - 9.9e-41 139.6 0.0 1.6e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52829.1 - 5.9e-23 81.2 0.0 2.4e-22 79.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY52829.1 - 6.3e-05 22.0 0.0 0.015 14.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EPY52829.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vac_ImportDeg PF09783.4 EPY52830.1 - 2.5e-50 170.3 1.5 3.1e-50 170.1 1.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein Glycoamylase PF10091.4 EPY52830.1 - 0.074 12.1 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative glucoamylase Pkinase PF00069.20 EPY52831.1 - 5.7e-62 209.2 0.0 1e-61 208.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52831.1 - 1.1e-32 113.1 0.0 2e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY52831.1 - 0.00015 20.8 0.0 0.00055 18.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPY52831.1 - 0.036 13.8 0.0 0.34 10.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L7Ae PF01248.21 EPY52832.1 - 6.2e-27 92.9 0.0 7.3e-27 92.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynamin_M PF01031.15 EPY52833.1 - 2.2e-101 338.5 0.0 3.3e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EPY52833.1 - 2e-52 177.4 0.1 6.3e-52 175.7 0.1 1.9 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EPY52833.1 - 4.8e-25 87.2 6.3 6.1e-25 86.9 3.4 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 EPY52833.1 - 0.0046 17.4 0.1 0.032 14.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EPY52833.1 - 0.014 15.3 0.5 0.11 12.4 0.3 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EPY52833.1 - 0.16 11.9 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain HlyIII PF03006.15 EPY52834.1 - 5.9e-63 212.2 25.1 7.1e-63 211.9 17.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 EPY52834.1 - 0.086 12.7 3.1 2.1 8.2 2.2 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) PAH PF02671.16 EPY52835.1 - 2e-41 139.3 8.4 4.7e-15 54.9 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EPY52835.1 - 8.1e-37 125.0 0.1 8.1e-37 125.0 0.1 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor SIS PF01380.17 EPY52836.1 - 8.3e-58 193.6 0.0 2.4e-33 114.5 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EPY52836.1 - 2.3e-27 95.6 0.1 9.6e-19 67.2 0.0 2.6 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPY52836.1 - 4.2e-16 59.1 0.0 8e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPY52836.1 - 3.5e-10 39.6 0.0 8.3e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EPY52836.1 - 1.1e-06 27.5 0.1 1.9e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glyoxalase PF00903.20 EPY52837.1 - 2.6e-42 143.8 0.5 2.5e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPY52837.1 - 4.2e-32 110.9 0.0 4.1e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EPY52837.1 - 1.4e-22 79.7 0.2 5.5e-09 36.0 0.0 3.8 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPY52837.1 - 2.6e-08 33.9 0.0 0.0028 17.5 0.0 3.9 1 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 EPY52837.1 - 0.0086 15.7 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal DUF440 PF04269.7 EPY52837.1 - 0.061 13.3 0.1 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF440 CppA_C PF14507.1 EPY52837.1 - 0.11 12.6 0.3 12 6.1 0.1 2.4 2 0 0 2 2 2 0 CppA C-terminal MFS_1 PF07690.11 EPY52838.1 - 3.7e-37 127.8 52.7 3.7e-37 127.8 36.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPY52838.1 - 6.6e-10 37.8 14.0 6.6e-10 37.8 9.7 2.3 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPY52838.1 - 1.1e-09 37.4 35.3 2.9e-09 36.0 11.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter ArfGap PF01412.13 EPY52839.1 - 3.6e-40 136.4 0.3 3.6e-40 136.4 0.2 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 EPY52839.1 - 4.5e-06 26.3 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain NMD3 PF04981.8 EPY52839.1 - 0.22 10.6 0.9 0.34 9.9 0.1 1.6 2 0 0 2 2 2 0 NMD3 family DIPSY PF11763.3 EPY52840.1 - 4.3e-35 120.1 2.9 7.3e-35 119.4 2.0 1.4 1 0 0 1 1 1 1 Cell-wall adhesin ligand-binding C-terminal Candida_ALS PF05792.8 EPY52840.1 - 0.93 9.6 40.6 0.096 12.8 12.2 3.4 3 0 0 3 3 3 0 Candida agglutinin-like (ALS) Cmc1 PF08583.5 EPY52842.1 - 4.5e-14 51.9 10.7 1.5e-13 50.3 7.4 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EPY52842.1 - 0.002 17.5 2.3 0.002 17.5 1.6 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3811 PF11656.3 EPY52842.1 - 0.0041 17.1 4.8 0.012 15.6 0.1 2.0 1 1 1 2 2 2 1 YjbD family (DUF3811) Cid2 PF09774.4 EPY52842.1 - 0.067 13.2 7.1 0.082 13.0 4.9 1.0 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Citrate_ly_lig PF08218.6 EPY52842.1 - 0.12 11.8 0.2 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain Tom37_C PF11801.3 EPY52842.1 - 0.37 10.6 5.3 0.42 10.4 3.7 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain GDNF PF02351.11 EPY52842.1 - 0.5 10.9 4.5 0.76 10.3 3.1 1.4 1 1 0 1 1 1 0 GDNF/GAS1 domain UTRA PF07702.8 EPY52843.1 - 0.067 12.7 0.0 0.87 9.1 0.0 2.1 1 1 1 2 2 2 0 UTRA domain zf-rbx1 PF12678.2 EPY52844.1 - 1e-08 35.1 3.6 1e-08 35.1 2.5 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPY52844.1 - 1.7e-08 34.1 8.4 1.7e-08 34.1 5.8 2.4 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 EPY52844.1 - 1.8e-06 27.7 5.2 6.6e-06 26.0 3.6 2.0 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EPY52844.1 - 9.9e-06 25.3 2.6 2.5e-05 24.0 1.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EPY52844.1 - 1.8e-05 24.2 8.7 1.8e-05 24.2 6.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY52844.1 - 0.00094 19.1 9.2 0.00094 19.1 6.4 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EPY52844.1 - 0.29 10.9 9.1 0.13 12.0 2.3 2.9 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.1 EPY52844.1 - 0.39 10.4 5.9 0.93 9.2 2.8 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EPY52844.1 - 0.45 10.2 14.2 0.0088 15.6 4.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EPY52844.1 - 1.3 9.1 16.3 0.011 15.7 5.5 2.1 2 0 0 2 2 1 0 RING-variant domain zf-RING_4 PF14570.1 EPY52844.1 - 5.4 6.6 12.0 0.35 10.4 3.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EPY52844.1 - 7.7 6.1 9.0 6.8 6.2 3.0 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Bromodomain PF00439.20 EPY52845.1 - 2.8e-18 65.6 0.1 1.2e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Bromodomain Ribosomal_S8e PF01201.17 EPY52845.1 - 0.029 14.4 0.1 0.19 11.8 0.1 2.0 1 1 0 1 1 1 0 Ribosomal protein S8e Euplotes_phero PF05842.6 EPY52845.1 - 0.094 13.0 0.5 0.24 11.7 0.2 1.8 1 1 1 2 2 2 0 Euplotes octocarinatus mating pheromone protein Ndc1_Nup PF09531.5 EPY52845.1 - 1.1 7.6 3.9 1.4 7.2 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_5 PF00266.14 EPY52846.1 - 7.3e-94 314.5 0.0 9e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPY52846.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EPY52846.1 - 0.00093 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family B12-binding PF02310.14 EPY52846.1 - 0.011 15.6 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain Radical_SAM PF04055.16 EPY52846.1 - 0.024 14.8 0.1 0.15 12.1 0.1 2.3 1 1 0 1 1 1 0 Radical SAM superfamily Pyridoxal_deC PF00282.14 EPY52846.1 - 0.032 12.6 0.0 0.056 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.13 EPY52847.1 - 2.9e-56 190.5 1.8 3.5e-56 190.2 1.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EPY52847.1 - 1.1e-14 53.5 0.0 1.9e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPY52847.1 - 2.8e-12 45.9 0.0 4.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPY52847.1 - 3.8e-11 42.2 0.0 7.4e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Med3 PF11593.3 EPY52847.1 - 0.00014 21.2 0.9 0.00018 20.9 0.6 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Vps5 PF09325.5 EPY52847.1 - 0.024 13.8 4.0 0.12 11.5 2.0 2.2 2 0 0 2 2 2 0 Vps5 C terminal like BRE1 PF08647.6 EPY52847.1 - 0.34 10.8 4.8 1.2 9.1 0.0 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Gag_spuma PF03276.9 EPY52847.1 - 8.6 4.5 8.2 12 4.1 5.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1325 PF07039.6 EPY52848.1 - 3.5e-31 107.5 0.0 4.8e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4254 PF14063.1 EPY52848.1 - 0.018 14.6 1.3 0.029 13.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) V_ATPase_I PF01496.14 EPY52848.1 - 0.055 11.3 0.1 0.07 10.9 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4537 PF15057.1 EPY52848.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF4384 PF14326.1 EPY52848.1 - 0.12 12.1 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) FUSC PF04632.7 EPY52848.1 - 0.13 10.6 0.1 0.17 10.3 0.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Galactosyl_T PF01762.16 EPY52849.1 - 1.2e-08 34.8 0.1 0.0038 16.8 0.0 3.2 2 1 0 2 2 2 2 Galactosyltransferase Fringe PF02434.11 EPY52849.1 - 0.037 13.2 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Fringe-like DUF3885 PF13021.1 EPY52849.1 - 0.056 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Peptidase_M1 PF01433.15 EPY52850.1 - 2.8e-131 438.2 0.1 6.4e-131 437.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EPY52850.1 - 1.1e-81 274.6 0.2 1.6e-81 274.0 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EPY52850.1 - 2.9e-18 66.1 0.2 4.9e-18 65.4 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_2 PF13646.1 EPY52850.1 - 0.1 12.9 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats LRR_4 PF12799.2 EPY52851.1 - 3.7e-07 29.6 7.0 0.00036 20.0 2.5 3.4 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EPY52851.1 - 0.00058 19.4 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EPY52851.1 - 0.0027 17.4 1.3 0.007 16.0 0.2 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EPY52851.1 - 0.014 15.2 0.5 58 4.3 0.0 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EPY52851.1 - 0.47 10.8 4.5 11 6.7 0.5 3.9 4 0 0 4 4 4 0 Leucine rich repeat Rad60-SLD PF11976.3 EPY52852.1 - 1.2e-21 76.1 0.1 2.5e-16 59.1 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPY52852.1 - 0.013 14.8 0.1 0.036 13.4 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin family Ribosomal_L35Ae PF01247.13 EPY52853.1 - 2.8e-41 139.1 0.1 3.2e-41 139.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EPY52853.1 - 0.0022 17.8 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Tachystatin_B PF11478.3 EPY52853.1 - 0.031 14.0 0.1 0.061 13.0 0.1 1.4 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B PLDc_2 PF13091.1 EPY52855.1 - 2e-12 46.9 0.0 4.1e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EPY52855.1 - 0.0044 16.7 3.3 0.24 11.2 0.0 3.2 3 0 0 3 3 3 1 Phospholipase D Active site motif MMS19_C PF12460.3 EPY52855.1 - 0.012 14.4 0.1 0.027 13.2 0.1 1.5 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Pkinase PF00069.20 EPY52856.1 - 1.3e-77 260.5 2.1 1.1e-42 146.0 0.0 4.0 4 1 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EPY52856.1 - 2e-59 201.0 9.3 2e-59 201.0 6.4 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EPY52856.1 - 2.4e-48 164.4 0.1 2e-23 82.8 0.0 4.2 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.17 EPY52856.1 - 5.9e-18 64.8 0.1 2.8e-17 62.6 0.1 2.3 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EPY52856.1 - 2.6e-10 39.8 0.0 6.3e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 EPY52856.1 - 2e-06 26.9 0.0 0.0047 15.9 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPY52856.1 - 4.8e-05 22.5 1.1 0.12 11.4 0.0 3.1 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPY52856.1 - 0.0011 18.7 0.2 0.061 13.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family LRR_2 PF07723.8 EPY52856.1 - 0.12 12.8 0.8 22 5.7 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat Syntaxin-6_N PF09177.6 EPY52857.1 - 1.2e-20 73.6 1.3 3.7e-19 68.9 0.1 2.4 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 EPY52857.1 - 1.2e-13 50.5 1.1 1.2e-13 50.5 0.7 2.8 3 0 0 3 3 3 1 SNARE domain Protoglobin PF11563.3 EPY52857.1 - 0.028 14.0 0.1 0.059 13.0 0.1 1.5 1 0 0 1 1 1 0 Protoglobin Sipho_Gp157 PF05565.6 EPY52857.1 - 0.045 13.3 0.3 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 MutS_III PF05192.13 EPY52857.1 - 0.067 12.9 1.8 2.3 7.9 0.2 2.1 1 1 1 2 2 2 0 MutS domain III DUF2299 PF10061.4 EPY52857.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) DUF745 PF05335.8 EPY52857.1 - 0.24 10.8 1.1 0.49 9.8 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Sec20 PF03908.8 EPY52857.1 - 0.28 10.9 3.7 0.66 9.7 0.6 2.6 2 1 1 3 3 3 0 Sec20 Baculo_PEP_C PF04513.7 EPY52857.1 - 3.4 7.4 7.6 11 5.8 0.8 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NAP PF00956.13 EPY52858.1 - 2.6e-31 108.6 9.7 2.6e-31 108.6 6.8 2.1 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EPY52858.1 - 0.078 13.1 7.7 0.23 11.6 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ERF PF04404.7 EPY52858.1 - 9.4 5.7 7.1 15 5.0 2.8 2.3 2 0 0 2 2 2 0 ERF superfamily GAS PF13851.1 EPY52859.1 - 0.00023 20.4 10.7 0.00028 20.1 7.4 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Tenui_NS3 PF05310.7 EPY52859.1 - 0.0081 16.0 2.2 0.34 10.7 0.1 2.2 2 0 0 2 2 2 1 Tenuivirus movement protein Herpes_TAF50 PF03326.8 EPY52859.1 - 0.01 14.8 2.1 0.013 14.4 1.5 1.1 1 0 0 1 1 1 1 Herpesvirus transcription activation factor (transactivator) Acylphosphatase PF00708.13 EPY52859.1 - 0.012 15.7 0.9 0.88 9.7 0.1 2.2 2 0 0 2 2 2 0 Acylphosphatase XLF PF09302.6 EPY52859.1 - 0.014 15.1 4.6 0.014 15.1 3.2 1.9 1 1 1 2 2 2 0 XLF (XRCC4-like factor) Fic_N PF13784.1 EPY52859.1 - 0.024 14.4 1.3 0.037 13.8 0.5 1.6 1 1 0 1 1 1 0 Fic/DOC family N-terminal PP-binding_2 PF14573.1 EPY52859.1 - 0.028 14.4 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Acyl-carrier DUF948 PF06103.6 EPY52859.1 - 0.034 13.9 1.1 0.069 13.0 0.6 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) 3H PF02829.9 EPY52859.1 - 0.041 13.9 0.3 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 3H domain DUF1342 PF07072.6 EPY52859.1 - 0.077 12.6 8.0 0.027 14.1 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) MCPsignal PF00015.16 EPY52859.1 - 0.12 11.9 3.9 0.15 11.6 2.7 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2205 PF10224.4 EPY52859.1 - 0.24 10.9 5.9 0.38 10.3 0.7 2.8 1 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) LXG PF04740.7 EPY52859.1 - 0.37 10.5 9.7 0.75 9.5 6.7 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily PspA_IM30 PF04012.7 EPY52859.1 - 0.56 9.5 9.6 0.18 11.1 1.3 2.1 1 1 1 2 2 2 0 PspA/IM30 family Shugoshin_N PF07558.6 EPY52859.1 - 0.63 9.7 6.3 3.1 7.5 4.4 2.1 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EPY52859.1 - 0.78 9.3 15.6 1 8.9 10.8 1.2 1 0 0 1 1 1 0 IncA protein THOC7 PF05615.8 EPY52859.1 - 0.95 9.7 10.0 1.3 9.3 6.9 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 SurA_N_2 PF13623.1 EPY52859.1 - 2.7 7.9 9.2 1.2 9.1 0.9 2.1 1 1 1 2 2 2 0 SurA N-terminal domain Seryl_tRNA_N PF02403.17 EPY52859.1 - 2.8 8.0 10.7 4.7 7.2 3.6 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Retrotrans_gag PF03732.12 EPY52859.1 - 4.2 7.4 5.8 8.8 6.4 3.2 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein zf-RING_2 PF13639.1 EPY52860.1 - 1.6e-08 34.2 2.9 1.6e-08 34.2 2.0 3.4 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.20 EPY52860.1 - 0.013 15.1 1.6 0.013 15.1 1.1 3.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPY52860.1 - 0.024 14.7 2.1 0.024 14.7 1.5 3.6 3 1 0 3 3 3 0 RING-H2 zinc finger FANCL_C PF11793.3 EPY52860.1 - 0.075 13.0 5.3 0.35 10.8 1.3 2.7 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EPY52860.1 - 0.27 11.0 16.4 0.66 9.7 1.5 4.0 4 0 0 4 4 4 0 zinc-RING finger domain Prok-RING_1 PF14446.1 EPY52860.1 - 0.61 9.8 19.9 0.34 10.6 2.9 4.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EPY52860.1 - 1.4 8.5 15.4 0.75 9.4 2.3 3.5 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain DUF164 PF02591.10 EPY52860.1 - 2.2 8.1 6.1 30 4.5 0.1 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain BIR PF00653.16 EPY52860.1 - 4.2 7.8 7.2 8 6.9 0.2 3.4 4 0 0 4 4 4 0 Inhibitor of Apoptosis domain zf-C3HC4_2 PF13923.1 EPY52860.1 - 5.7 7.0 17.3 0.091 12.8 2.4 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Dus PF01207.12 EPY52861.1 - 7.1e-70 235.2 0.0 8.1e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Sec63 PF02889.11 EPY52862.1 - 1.2e-28 100.2 0.1 8.4e-25 87.6 0.0 2.3 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 EPY52862.1 - 3.5e-16 58.6 0.2 6.4e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Svf1 PF08622.5 EPY52863.1 - 3.2e-54 184.1 1.4 3.7e-54 183.8 1.0 1.0 1 0 0 1 1 1 1 Svf1-like SecY PF00344.15 EPY52864.1 - 1.1e-45 156.1 21.5 1.5e-45 155.6 14.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EPY52864.1 - 0.0019 17.6 0.0 0.0019 17.6 0.0 3.5 5 0 0 5 5 5 1 Plug domain of Sec61p Med26 PF08711.6 EPY52865.1 - 5.8e-08 32.1 1.1 5.8e-08 32.1 0.8 3.5 4 1 0 4 4 4 1 TFIIS helical bundle-like domain Tom5 PF10642.4 EPY52866.1 - 2.4e-06 27.1 0.0 2.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EPY52867.1 - 2.2e-39 134.3 1.8 2.2e-39 134.3 1.3 1.8 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EPY52867.1 - 4.1 7.6 56.3 1.7e+03 -0.8 39.1 2.3 1 1 0 1 1 1 0 Nucleoporin FG repeat region COG5 PF10392.4 EPY52868.1 - 1.6e-26 92.8 3.6 5.8e-26 91.0 2.5 2.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 IncA PF04156.9 EPY52868.1 - 0.023 14.2 0.2 0.063 12.8 0.1 1.7 1 0 0 1 1 1 0 IncA protein TSA PF03249.8 EPY52868.1 - 0.057 11.9 0.1 0.085 11.3 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen Ferrochelatase PF00762.14 EPY52868.1 - 0.06 12.2 1.7 0.062 12.2 0.4 1.6 2 0 0 2 2 2 0 Ferrochelatase OGG_N PF07934.7 EPY52868.1 - 1.2 9.1 4.8 1.1 9.2 0.4 2.7 1 1 1 3 3 3 0 8-oxoguanine DNA glycosylase, N-terminal domain TRF PF08558.5 EPY52869.1 - 7.2e-67 225.2 0.1 9.8e-67 224.7 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EPY52869.1 - 2.7e-06 27.3 0.4 4.8e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY52869.1 - 0.0067 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PAT1 PF09770.4 EPY52871.1 - 9.2e-198 659.2 13.8 4.1e-197 657.0 9.6 1.7 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Peptidase_C48 PF02902.14 EPY52872.1 - 2.1e-32 112.5 0.2 3.9e-32 111.6 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Arrestin_C PF02752.17 EPY52873.1 - 3.9e-09 36.7 0.6 2.1e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain PPR_2 PF13041.1 EPY52874.1 - 2.3e-12 46.7 0.4 4.7e-05 23.2 0.0 4.2 2 1 2 4 4 4 3 PPR repeat family PPR PF01535.15 EPY52874.1 - 5.6e-11 41.6 0.9 0.005 16.7 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 EPY52874.1 - 1.6e-07 31.0 0.2 0.033 14.4 0.0 4.7 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EPY52874.1 - 0.016 14.6 1.8 0.23 10.9 0.0 3.2 4 0 0 4 4 4 0 PPR repeat GFRP PF06399.8 EPY52874.1 - 0.074 12.6 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) SRF-TF PF00319.13 EPY52875.1 - 7.9e-17 60.2 0.2 1.7e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Glucan_synthase PF02364.10 EPY52876.1 - 0 1310.4 0.0 0 1309.9 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPY52876.1 - 1.8e-37 127.8 1.3 3.8e-37 126.7 0.9 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.4 EPY52877.1 - 3.7e-38 130.6 4.5 1.3e-37 128.9 2.7 1.9 2 0 0 2 2 2 1 SprT-like family HMG_box PF00505.14 EPY52877.1 - 0.00047 20.3 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box Tox-MPTase2 PF15638.1 EPY52877.1 - 0.1 12.0 1.1 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Metallopeptidase toxin 2 Ribosomal_S30 PF04758.9 EPY52878.1 - 4.2e-28 96.8 5.4 4.5e-28 96.7 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Aminotran_4 PF01063.14 EPY52879.1 - 3.8e-28 98.5 0.0 4.8e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MutS_V PF00488.16 EPY52880.1 - 9.3e-96 319.7 2.5 1.1e-95 319.4 0.3 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EPY52880.1 - 2.2e-34 119.0 1.4 5.3e-34 117.7 0.9 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EPY52880.1 - 3.4e-19 69.2 0.5 1.8e-18 66.8 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EPY52880.1 - 9.7e-19 67.3 1.3 2.3e-18 66.1 0.9 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EPY52880.1 - 5.4e-13 48.9 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain I G10 PF01125.12 EPY52881.1 - 1.4e-63 212.7 3.1 1.6e-63 212.5 2.1 1.0 1 0 0 1 1 1 1 G10 protein DUF2013 PF09431.5 EPY52882.1 - 2.2e-44 150.5 5.3 2.2e-44 150.5 3.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) COX6B PF02297.12 EPY52883.1 - 1.6e-19 69.6 10.8 1.9e-19 69.4 7.5 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EPY52883.1 - 0.24 11.4 4.2 0.56 10.2 2.9 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 XFP_N PF09364.5 EPY52884.1 - 9.5e-167 554.3 0.0 1.2e-166 553.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EPY52884.1 - 1.1e-73 246.6 0.0 1.7e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EPY52884.1 - 1.2e-63 214.2 0.7 1.6e-63 213.8 0.0 1.5 2 0 0 2 2 2 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EPY52884.1 - 0.076 12.5 0.1 0.58 9.7 0.1 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Folliculin PF11704.3 EPY52885.1 - 5.3e-53 179.0 0.1 8.5e-53 178.3 0.1 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CDC14 PF08045.6 EPY52886.1 - 1.3e-59 201.4 4.6 6.3e-59 199.1 3.2 1.8 1 1 0 1 1 1 1 Cell division control protein 14, SIN component G-alpha PF00503.15 EPY52887.1 - 3.3e-105 351.9 0.0 3.8e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPY52887.1 - 8.9e-13 47.8 0.1 6.4e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EPY52887.1 - 0.0063 16.0 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EPY52887.1 - 0.0071 16.8 0.0 5.6 7.4 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EPY52887.1 - 0.07 12.2 1.7 2.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EPY52887.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Coatomer_E PF04733.9 EPY52888.1 - 9.1e-68 228.5 2.5 1.1e-67 228.3 1.7 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 EPY52888.1 - 0.00068 19.3 2.4 7 6.8 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52888.1 - 0.0022 17.8 10.0 0.072 13.0 1.8 3.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPY52888.1 - 0.022 14.3 9.1 1.8 8.2 0.3 3.8 3 1 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 EPY52888.1 - 0.034 13.7 2.0 36 4.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Type_III_YscG PF09477.5 EPY52888.1 - 0.1 12.7 0.3 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Apc3 PF12895.2 EPY52888.1 - 0.35 11.0 7.6 11 6.1 0.6 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPY52888.1 - 0.99 10.1 7.4 5 7.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52888.1 - 1.7 9.0 12.9 0.91 9.9 0.4 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52888.1 - 6.3 7.7 9.4 5 8.0 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.17 EPY52889.1 - 2.8e-103 345.7 0.0 3.4e-103 345.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_2b PF00587.20 EPY52890.1 - 1.2e-38 132.4 0.0 1.7e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPY52890.1 - 1.8e-10 40.6 0.0 4.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EPY52890.1 - 0.031 13.0 0.1 0.074 11.8 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) zf-H2C2_2 PF13465.1 EPY52890.1 - 5.6 7.4 6.0 6.9 7.1 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EPY52890.1 - 6.6 6.7 6.5 36 4.4 3.0 2.4 1 1 1 2 2 2 0 Zinc ribbon domain DEAD PF00270.24 EPY52891.1 - 6.8e-39 133.0 0.3 1.8e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPY52891.1 - 5e-20 70.8 0.0 1.2e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPY52891.1 - 4.1e-18 65.0 0.0 1.6e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY52891.1 - 1.1e-05 25.3 0.0 1.1e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPY52891.1 - 0.0029 17.3 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ubiquitin PF00240.18 EPY52892.1 - 2.1e-25 87.8 0.0 2.4e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPY52892.1 - 5.1e-16 58.1 0.0 5.5e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPY52892.1 - 3e-05 24.2 0.1 6.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EPY52892.1 - 0.059 13.5 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CTDII PF01556.13 EPY52892.1 - 0.12 12.3 0.2 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain DUF999 PF06198.6 EPY52895.1 - 2.9e-13 49.7 3.5 4.2e-12 46.0 2.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF999) EmrE PF13536.1 EPY52895.1 - 1.3 9.2 7.9 1.7 8.8 5.5 1.2 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Sod_Fe_C PF02777.13 EPY52896.1 - 9e-20 70.4 2.1 4.5e-19 68.2 1.4 1.9 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Phospholip_A2_3 PF09056.6 EPY52896.1 - 0.048 13.8 0.8 0.98 9.6 0.0 2.2 1 1 1 2 2 2 0 Prokaryotic phospholipase A2 MBOAT_2 PF13813.1 EPY52897.1 - 2.1e-13 50.1 2.6 6.6e-13 48.5 1.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RCC1 PF00415.13 EPY52898.1 - 6.7e-14 51.8 0.9 0.00015 21.9 0.0 4.3 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPY52898.1 - 3.2e-08 32.9 10.7 2e-05 24.0 0.5 5.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EPY52898.1 - 3.3e-06 26.6 0.3 8.1e-06 25.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPY52898.1 - 9.2e-06 25.1 0.6 1.8e-05 24.2 0.4 1.5 1 0 0 1 1 1 1 F-box domain HAD PF12710.2 EPY52899.1 - 2.5e-15 57.1 0.1 4.7e-15 56.2 0.1 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPY52899.1 - 7.5e-12 46.1 1.0 4.1e-10 40.4 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPY52899.1 - 1.3e-10 41.3 0.3 4.1e-07 29.8 0.1 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPY52899.1 - 5.9e-06 25.6 0.0 4.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 EPY52899.1 - 0.00013 22.2 0.0 0.0006 20.0 0.0 2.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EPY52899.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.2 EPY52899.1 - 0.059 13.0 0.0 0.54 9.8 0.0 2.5 2 1 0 2 2 2 0 Acid Phosphatase zf-DHHC PF01529.15 EPY52901.1 - 1.5e-34 118.8 5.3 1.5e-34 118.8 3.7 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Rtt102p PF09510.5 EPY52902.1 - 0.00025 21.0 4.6 0.00025 21.0 3.2 1.1 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein DUF2348 PF09807.4 EPY52903.1 - 1.4e-10 40.7 0.0 5.1e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 EPY52903.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 Elongator subunit Iki1 Methyltransf_23 PF13489.1 EPY52904.1 - 7.3e-18 64.7 0.1 9.2e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY52904.1 - 7.9e-16 58.3 0.0 1.7e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY52904.1 - 3.4e-14 52.6 0.0 6.9e-14 51.6 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY52904.1 - 5.3e-11 42.8 0.0 3.2e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY52904.1 - 5.6e-11 43.0 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY52904.1 - 9.9e-09 35.4 0.0 2.8e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPY52904.1 - 3.3e-07 29.8 0.0 7.5e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPY52904.1 - 7e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EPY52904.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FmrO PF07091.6 EPY52904.1 - 0.00024 20.2 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 EPY52904.1 - 0.00056 19.1 0.0 0.0013 17.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TPMT PF05724.6 EPY52904.1 - 0.00077 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CheR PF01739.13 EPY52904.1 - 0.0012 18.1 0.0 1.3 8.2 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.12 EPY52904.1 - 0.049 12.5 0.0 1.3 7.9 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EPY52904.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase Rogdi_lz PF10259.4 EPY52905.1 - 8.6e-23 80.8 2.5 8.4e-19 67.7 0.6 2.1 2 0 0 2 2 2 2 Rogdi leucine zipper containing protein Matrilin_ccoil PF10393.4 EPY52905.1 - 0.091 12.1 0.8 0.35 10.2 0.1 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FHA PF00498.21 EPY52906.1 - 4.6e-18 65.1 0.0 9.9e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EPY52907.1 - 0.036 14.2 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 EPY52908.1 - 9.4e-39 133.1 0.0 1.3e-38 132.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52908.1 - 1.4e-14 53.8 0.0 2.6e-14 52.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EPY52908.1 - 2.2e-06 27.6 0.0 0.0019 18.0 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPY52908.1 - 0.036 12.8 0.1 0.057 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Beach PF02138.13 EPY52909.1 - 2.7e-109 364.8 0.5 6.1e-109 363.6 0.4 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EPY52909.1 - 1.2e-10 41.1 0.1 4.1e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EPY52909.1 - 1.2e-08 34.4 2.6 0.016 15.1 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat FYVE PF01363.16 EPY52909.1 - 3.6e-05 23.5 9.8 0.00011 22.0 6.8 1.8 1 0 0 1 1 1 1 FYVE zinc finger Laminin_G_3 PF13385.1 EPY52909.1 - 0.049 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily FYVE_2 PF02318.11 EPY52909.1 - 0.082 12.8 7.2 0.28 11.0 5.0 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger RRM_1 PF00076.17 EPY52910.1 - 1.8e-07 30.6 0.0 4e-05 23.1 0.0 3.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52910.1 - 4.1e-05 23.4 0.0 0.00038 20.3 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52910.1 - 5.7e-05 22.8 0.1 0.00053 19.7 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 EPY52910.1 - 0.00082 17.4 10.2 0.00082 17.4 7.1 1.5 2 0 0 2 2 2 1 Nop14-like family RhoGAP PF00620.22 EPY52912.1 - 1.1e-41 142.0 0.1 3.8e-41 140.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EPY52912.1 - 8.3e-20 70.6 24.0 1.1e-10 41.3 3.3 2.5 2 0 0 2 2 2 2 LIM domain DUF3450 PF11932.3 EPY52912.1 - 0.006 15.8 0.3 0.011 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF904 PF06005.7 EPY52912.1 - 0.0087 16.3 0.7 0.065 13.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF904) DUF972 PF06156.8 EPY52912.1 - 0.0092 16.3 2.3 0.084 13.2 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 EPY52912.1 - 0.051 13.3 5.7 1.5 8.5 2.7 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Mst1_SARAH PF11629.3 EPY52912.1 - 0.071 12.9 0.3 0.071 12.9 0.2 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF1364 PF07102.7 EPY52912.1 - 0.084 12.7 9.9 2.1 8.2 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) ATG16 PF08614.6 EPY52912.1 - 0.36 10.6 7.6 0.052 13.3 1.8 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) KH_1 PF00013.24 EPY52913.1 - 0.00015 21.3 0.1 0.016 14.8 0.0 3.5 3 0 0 3 3 3 1 KH domain KH_3 PF13014.1 EPY52913.1 - 0.026 14.1 0.1 0.66 9.6 0.0 3.0 2 0 0 2 2 2 0 KH domain Apc13p PF05839.6 EPY52914.1 - 1.2e-25 89.2 0.3 1.7e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Apc13p protein Exo_endo_phos PF03372.18 EPY52915.1 - 4.3e-32 112.0 0.0 5.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CDC37_N PF03234.9 EPY52916.1 - 6.4e-52 176.4 14.6 6.4e-52 176.4 10.1 2.7 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EPY52916.1 - 2.9e-38 131.0 3.3 2.9e-38 131.0 2.3 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EPY52916.1 - 1.2e-22 79.6 0.2 1.2e-22 79.6 0.1 3.1 2 1 0 2 2 2 1 Cdc37 C terminal domain ABC_membrane PF00664.18 EPY52917.1 - 1.3e-43 149.3 9.4 1.8e-43 148.9 6.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EPY52917.1 - 2.9e-30 105.3 0.0 5.5e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EPY52917.1 - 4.2e-05 22.8 0.0 7.7e-05 22.0 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Clathrin_lg_ch PF01086.12 EPY52918.1 - 1.7e-55 188.3 14.1 1.9e-55 188.2 9.8 1.0 1 0 0 1 1 1 1 Clathrin light chain FliD_C PF07195.7 EPY52918.1 - 0.018 14.3 0.6 0.026 13.8 0.4 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF2346 PF09803.4 EPY52918.1 - 1.4 8.8 8.7 0.79 9.6 0.7 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2346) Nop52 PF05997.7 EPY52919.1 - 2.9e-60 203.3 4.7 3.6e-60 203.0 3.3 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Ribosomal_L18e PF00828.14 EPY52920.1 - 5.7e-11 42.8 0.2 9.2e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 LSM PF01423.17 EPY52921.1 - 1.7e-16 59.4 0.0 2.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF3574 PF12098.3 EPY52921.1 - 0.0098 15.4 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3574) LXG PF04740.7 EPY52921.1 - 0.087 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily GTP_EFTU PF00009.22 EPY52922.1 - 1.1e-59 200.9 0.5 1.6e-59 200.5 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPY52922.1 - 5.8e-26 90.5 0.0 1.3e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPY52922.1 - 1.7e-16 60.1 1.3 3.7e-16 59.0 0.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPY52922.1 - 9e-06 25.2 0.5 2.1e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPY52922.1 - 6.2e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPY52922.1 - 0.0011 19.4 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein FYVE PF01363.16 EPY52923.1 - 1.6e-15 56.6 10.2 3.1e-15 55.8 7.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EPY52923.1 - 2.9 7.8 14.5 6.1 6.8 10.1 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger LDB19 PF13002.2 EPY52924.1 - 1.3e-58 197.6 0.1 2.5e-58 196.7 0.1 1.4 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 EPY52924.1 - 9.2e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Atg14 PF10186.4 EPY52925.1 - 2.6e-16 59.4 3.4 5.1e-16 58.4 2.3 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Exotox-A_bind PF09101.5 EPY52925.1 - 0.042 12.9 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Exotoxin A binding Apc3 PF12895.2 EPY52925.1 - 0.72 10.0 8.4 1.6 8.9 5.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Mhr1 PF12829.2 EPY52926.1 - 6.7e-16 57.8 0.1 1.1e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination IMS_C PF11799.3 EPY52926.1 - 0.05 13.5 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain AA_permease PF00324.16 EPY52927.1 - 2.6e-53 181.0 37.0 3.1e-53 180.7 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EPY52928.1 - 1.7e-65 220.7 0.0 2.5e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52928.1 - 1.1e-23 83.6 0.0 2.1e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY52928.1 - 0.14 11.8 0.2 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S9 PF00380.14 EPY52929.1 - 6.7e-38 129.6 0.5 7.6e-38 129.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Exo70 PF03081.10 EPY52929.1 - 0.18 10.5 0.3 0.23 10.2 0.2 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Ribosomal_S11 PF00411.14 EPY52930.1 - 1.3e-40 138.0 1.3 1.5e-40 137.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L30_N PF08079.7 EPY52931.1 - 2.3e-23 82.0 14.0 4.5e-23 81.0 9.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EPY52931.1 - 6.4e-19 67.2 1.2 1.8e-18 65.8 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e PPR_2 PF13041.1 EPY52932.1 - 1.1e-20 73.2 0.9 4e-15 55.5 0.1 3.3 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EPY52932.1 - 2e-05 24.5 2.9 0.42 11.0 0.1 4.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 EPY52932.1 - 2.1e-05 24.1 8.0 0.12 12.3 0.1 4.5 4 0 0 4 4 4 2 PPR repeat Apc3 PF12895.2 EPY52932.1 - 0.0086 16.1 4.0 0.74 9.9 0.1 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 CHAT PF12770.2 EPY52932.1 - 0.071 12.2 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 CHAT domain PPR_1 PF12854.2 EPY52932.1 - 0.1 12.1 0.5 0.49 9.9 0.0 2.4 3 0 0 3 3 3 0 PPR repeat DUF572 PF04502.8 EPY52933.1 - 1.3e-46 159.3 13.3 1.8e-45 155.5 9.2 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-CHY PF05495.7 EPY52934.1 - 1.9e-15 56.7 15.9 1.9e-15 56.7 11.0 3.7 4 0 0 4 4 4 2 CHY zinc finger Ski_Sno PF02437.12 EPY52934.1 - 0.0035 16.8 0.4 0.015 14.8 0.3 2.1 1 0 0 1 1 1 1 SKI/SNO/DAC family DUF4391 PF14335.1 EPY52934.1 - 0.016 14.5 0.2 0.024 14.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Cys_rich_KTR PF14205.1 EPY52934.1 - 4.7 6.7 8.1 0.82 9.1 0.4 3.4 3 1 0 3 3 3 0 Cysteine-rich KTR UCH PF00443.24 EPY52935.1 - 2.3e-60 203.9 0.0 3.3e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY52935.1 - 6.8e-22 78.2 0.1 1.3e-21 77.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rad50_zn_hook PF04423.9 EPY52935.1 - 8.9 5.8 7.8 0.18 11.2 0.6 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-U1 PF06220.7 EPY52936.1 - 1.3e-11 43.8 0.7 2.3e-11 43.0 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-Dof PF02701.10 EPY52936.1 - 0.065 13.1 0.4 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Dof domain, zinc finger WD40 PF00400.27 EPY52937.1 - 1.1e-18 66.3 1.3 1.6e-10 40.4 0.0 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40 PF00400.27 EPY52938.1 - 2.1e-24 84.4 11.8 2e-09 36.9 0.2 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat RRM_1 PF00076.17 EPY52939.1 - 2.2e-14 52.8 0.0 3.4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52939.1 - 6.6e-14 51.6 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52939.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tir_receptor_C PF07489.6 EPY52939.1 - 1.8 8.2 7.0 3 7.5 4.8 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus eIF3g PF12353.3 EPY52940.1 - 2.3e-44 150.4 2.1 3.4e-44 149.8 1.5 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EPY52940.1 - 3.7e-18 64.9 0.0 7e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52940.1 - 5.4e-13 48.7 0.0 1.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY52940.1 - 1.7e-07 31.0 0.0 4.8e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EPY52941.1 - 2.6e-85 286.3 0.0 3.5e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPY52941.1 - 0.083 13.8 0.1 0.24 12.3 0.1 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Xpo1 PF08389.7 EPY52942.1 - 1.1e-25 90.2 0.1 1.1e-25 90.2 0.1 3.8 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EPY52942.1 - 9.4e-11 41.4 0.6 4.5e-10 39.3 0.3 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain LSM PF01423.17 EPY52943.1 - 7.2e-11 41.4 0.2 9.7e-11 41.0 0.1 1.4 1 1 0 1 1 1 1 LSM domain RNA_polI_A34 PF08208.6 EPY52944.1 - 1.1e-18 67.7 22.3 1.1e-18 67.7 15.5 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Sedlin_N PF04628.8 EPY52945.1 - 5.9e-46 155.6 0.3 6.6e-46 155.4 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EPY52945.1 - 3.7e-10 39.6 0.2 2.9e-09 36.7 0.2 1.9 1 1 0 2 2 2 1 Sybindin-like family RNA_pol_Rpb5_N PF03871.9 EPY52945.1 - 0.011 16.0 0.2 0.016 15.5 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Ribosomal_L10 PF00466.15 EPY52946.1 - 1.2e-18 66.8 0.0 1.8e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 EF-hand_4 PF12763.2 EPY52947.1 - 3.6e-42 142.3 0.0 1.6e-37 127.3 0.0 2.7 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 EPY52947.1 - 7e-39 133.4 5.5 3.1e-38 131.3 3.8 1.8 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 EPY52947.1 - 4.8e-05 22.3 0.7 0.00014 20.9 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EPY52947.1 - 0.0003 20.3 0.1 0.0061 16.1 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EPY52947.1 - 0.0034 17.1 0.8 0.029 14.2 0.5 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EPY52947.1 - 0.0067 16.5 0.1 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 EPY52947.1 - 0.048 13.0 1.3 0.12 11.8 0.9 1.7 1 0 0 1 1 1 0 EF hand Atg14 PF10186.4 EPY52947.1 - 0.064 12.1 1.6 0.1 11.5 1.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 EPY52947.1 - 0.2 11.3 3.3 0.68 9.6 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EPY52947.1 - 2.3 7.7 8.3 1.8 8.1 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator Fis1_TPR_C PF14853.1 EPY52948.1 - 7.1e-17 61.0 2.6 1.2e-16 60.3 1.8 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EPY52948.1 - 1e-10 40.6 0.1 1.7e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_6 PF13174.1 EPY52948.1 - 1.9e-05 24.7 1.6 4.4e-05 23.6 0.6 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPY52948.1 - 3.5e-05 23.3 0.5 0.00019 21.0 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPY52948.1 - 0.00045 20.6 0.1 0.0018 18.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPY52948.1 - 0.00048 20.0 1.0 0.024 14.5 0.6 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY52948.1 - 0.00053 20.2 1.5 0.00086 19.5 1.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPY52948.1 - 0.0013 18.2 0.6 0.0033 16.9 0.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPY52948.1 - 0.0051 17.4 0.3 0.0096 16.5 0.1 1.6 2 0 0 2 2 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EPY52948.1 - 0.0052 16.8 1.9 0.3 11.2 0.4 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EPY52948.1 - 0.018 14.6 0.6 0.036 13.6 0.4 1.6 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.1 EPY52948.1 - 0.021 14.6 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPY52948.1 - 0.25 11.6 2.2 36 4.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 EPY52949.1 - 1e-17 63.8 5.4 1.2e-17 63.5 3.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit RasGAP_C PF03836.10 EPY52949.1 - 0.00023 20.8 1.0 0.00023 20.8 0.7 1.7 2 0 0 2 2 2 1 RasGAP C-terminus Peptidase_M18 PF02127.10 EPY52949.1 - 0.013 14.0 0.2 0.013 14.0 0.2 1.1 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) DivIC PF04977.10 EPY52949.1 - 0.025 14.0 4.7 0.66 9.4 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator Rsa3 PF14615.1 EPY52949.1 - 0.083 12.1 0.3 0.68 9.2 0.0 2.2 1 1 1 2 2 2 0 Ribosome-assembly protein 3 DUF4558 PF15104.1 EPY52949.1 - 0.38 10.7 3.6 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) DUF724 PF05266.9 EPY52949.1 - 0.46 10.0 3.5 0.63 9.6 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Apolipoprotein PF01442.13 EPY52949.1 - 0.47 9.9 4.2 0.72 9.3 2.9 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FliT PF05400.8 EPY52949.1 - 0.49 10.8 5.3 12 6.4 1.1 2.3 2 0 0 2 2 2 0 Flagellar protein FliT HSCB_C PF07743.8 EPY52949.1 - 0.79 10.2 5.9 0.49 10.8 0.3 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain WXG100 PF06013.7 EPY52949.1 - 1 9.3 4.2 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4225 PF13988.1 EPY52949.1 - 1.2 8.5 3.5 9.7 5.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Cep57_CLD_2 PF14197.1 EPY52949.1 - 1.3 9.0 6.3 0.27 11.2 0.4 2.5 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF904 PF06005.7 EPY52949.1 - 1.4 9.2 6.6 0.25 11.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF2935 PF11155.3 EPY52949.1 - 1.5 8.9 3.8 13 5.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) TMF_DNA_bd PF12329.3 EPY52949.1 - 2.1 8.1 8.5 0.14 12.0 0.7 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EPY52949.1 - 5.2 7.0 9.5 0.46 10.4 0.5 2.2 2 0 0 2 2 2 0 FlxA-like protein XhlA PF10779.4 EPY52949.1 - 9.3 6.2 6.4 0.95 9.4 0.8 2.0 2 1 0 2 2 2 0 Haemolysin XhlA zf-H2C2_2 PF13465.1 EPY52950.1 - 1.6e-10 40.7 13.7 2.1e-05 24.5 2.9 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPY52950.1 - 5e-08 32.8 11.9 0.00071 19.7 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY52950.1 - 3e-05 24.0 11.7 0.029 14.6 2.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Cyclin PF08613.6 EPY52951.1 - 4.1e-07 30.5 0.1 7.5e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPY52951.1 - 0.098 12.2 0.2 0.25 10.9 0.2 1.8 1 1 0 1 1 1 0 Cyclin, N-terminal domain RRM_1 PF00076.17 EPY52952.1 - 5e-13 48.4 0.0 8.5e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY52952.1 - 2.4e-11 43.4 0.0 3.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPY52952.1 - 1.4e-07 31.8 1.2 1.4e-07 31.8 0.8 2.6 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EPY52952.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EPY52953.1 - 1.2e-69 234.3 0.0 2.6e-69 233.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY52953.1 - 4.1e-50 170.2 0.0 7e-49 166.2 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EPY52953.1 - 3.7e-15 55.7 0.0 9.4e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EPY52953.1 - 2.5e-14 52.8 0.1 3.2e-13 49.2 0.0 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EPY52953.1 - 1.6e-09 37.1 0.0 3.1e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_1 PF00536.25 EPY52953.1 - 4.6e-08 33.1 0.1 1.5e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Seadorna_VP7 PF07387.6 EPY52953.1 - 0.013 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EPY52953.1 - 0.057 13.1 0.0 0.67 9.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L5_C PF00673.16 EPY52954.1 - 2e-20 72.3 0.0 3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPY52954.1 - 0.0003 20.4 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 EST1_DNA_bind PF10373.4 EPY52955.1 - 3.9e-26 91.8 4.0 3.9e-26 91.8 2.8 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EPY52955.1 - 2e-20 73.0 7.2 3.4e-19 69.1 5.0 2.9 1 1 0 1 1 1 1 Telomerase activating protein Est1 Auxin_repressed PF05564.7 EPY52955.1 - 0.022 15.3 1.1 0.077 13.6 0.8 2.0 1 0 0 1 1 1 0 Dormancy/auxin associated protein Ribosomal_L22 PF00237.14 EPY52956.1 - 1.8e-31 108.1 0.1 2.9e-31 107.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CBF_beta PF02312.12 EPY52956.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit Oxysterol_BP PF01237.13 EPY52957.1 - 1.4e-126 421.7 0.0 1.4e-126 421.7 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EPY52957.1 - 2.3e-20 72.1 2.0 3.4e-10 39.8 0.4 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPY52957.1 - 1.6e-19 70.0 2.0 4e-11 43.0 0.9 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.24 EPY52957.1 - 3.5e-14 52.8 0.4 1.6e-13 50.7 0.0 2.3 3 0 0 3 3 3 1 PH domain Ank_3 PF13606.1 EPY52957.1 - 3.5e-13 48.3 2.9 0.00042 20.2 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.25 EPY52957.1 - 3.6e-13 48.5 0.5 0.00011 21.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EPY52957.1 - 3.7e-13 49.5 3.8 0.00058 20.3 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) PH_8 PF15409.1 EPY52957.1 - 2.8e-07 30.4 0.5 8.8e-07 28.9 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain CENP-T PF15511.1 EPY52957.1 - 0.022 14.0 15.5 0.041 13.1 10.7 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ribosomal_L2_C PF03947.13 EPY52958.1 - 1.1e-37 128.7 3.9 1.2e-37 128.6 2.1 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPY52958.1 - 2.5e-15 56.1 0.0 5.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain mRNA_cap_enzyme PF01331.14 EPY52959.1 - 1.2e-58 197.9 0.1 1.7e-58 197.4 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EPY52959.1 - 8.8e-27 93.5 0.3 1.7e-26 92.5 0.2 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EPY52959.1 - 2e-05 24.0 0.2 0.0011 18.3 0.1 2.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain HeLo PF14479.1 EPY52959.1 - 0.099 12.3 1.9 0.16 11.7 1.3 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation bZIP_1 PF00170.16 EPY52960.1 - 3.7e-08 33.1 9.5 5.7e-08 32.6 6.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPY52960.1 - 0.00077 19.2 8.7 0.0022 17.7 6.0 1.8 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPY52960.1 - 0.019 15.2 4.0 0.035 14.4 2.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor PBP PF01161.15 EPY52961.1 - 1.5e-11 44.3 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein COX7a PF02238.10 EPY52963.1 - 0.00033 20.3 0.4 0.00041 20.0 0.3 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIa CactinC_cactus PF09732.4 EPY52964.1 - 1.4e-49 166.8 0.7 1.4e-49 166.8 0.5 2.4 3 0 0 3 3 3 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EPY52964.1 - 6.5e-36 123.3 1.2 1e-35 122.7 0.8 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin DUF1087 PF06465.8 EPY52964.1 - 0.31 10.9 5.3 0.067 13.1 0.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Kinesin PF00225.18 EPY52965.1 - 4.9e-115 383.8 0.0 8.2e-115 383.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain SurA_N_3 PF13624.1 EPY52965.1 - 0.0062 16.5 0.5 0.74 9.7 0.2 2.5 2 0 0 2 2 2 2 SurA N-terminal domain IMPDH PF00478.20 EPY52966.1 - 1.2e-136 455.2 1.0 1.5e-136 454.9 0.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EPY52966.1 - 2.2e-19 68.9 0.4 8.3e-09 35.1 0.0 2.9 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EPY52966.1 - 2.1e-08 33.4 0.5 3.5e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EPY52966.1 - 2.2e-07 30.3 6.2 5.2e-05 22.5 3.9 2.5 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EPY52966.1 - 5.8e-05 22.4 2.0 0.00018 20.8 1.4 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.12 EPY52966.1 - 0.0018 17.1 0.3 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Aldolase PF01081.14 EPY52966.1 - 0.015 14.5 0.2 0.051 12.7 0.1 1.8 1 1 0 1 1 1 0 KDPG and KHG aldolase CHB_HEX PF03173.8 EPY52966.1 - 0.03 13.7 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative carbohydrate binding domain ThiG PF05690.9 EPY52966.1 - 0.043 12.8 2.1 0.1 11.6 0.4 2.0 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EPY52966.1 - 0.049 12.5 2.3 0.11 11.4 1.6 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase zf-DHHC PF01529.15 EPY52967.1 - 7.7e-35 119.8 14.7 7.7e-35 119.8 10.2 2.5 2 1 1 3 3 3 1 DHHC palmitoyltransferase Trp_halogenase PF04820.9 EPY52967.1 - 0.084 11.4 0.1 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MFS_1 PF07690.11 EPY52968.1 - 6.3e-42 143.5 53.4 1e-40 139.5 36.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPY52968.1 - 3e-16 58.7 24.9 3.9e-16 58.3 17.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPY52968.1 - 7.8e-16 57.6 8.0 7.8e-16 57.6 5.6 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter Xan_ur_permease PF00860.15 EPY52969.1 - 1.5e-63 214.6 30.6 2.5e-63 213.9 21.2 1.3 1 0 0 1 1 1 1 Permease family OCD_Mu_crystall PF02423.10 EPY52970.1 - 4.1e-45 153.9 0.0 5.3e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EPY52970.1 - 3.9e-08 33.4 0.0 5.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase HWE_HK PF07536.9 EPY52970.1 - 0.024 15.0 0.1 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 HWE histidine kinase THF_DHG_CYH_C PF02882.14 EPY52970.1 - 0.026 13.5 0.1 0.047 12.7 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AIRC PF00731.15 EPY52971.1 - 0.015 14.5 3.3 1.9 7.7 0.0 2.9 1 1 2 3 3 3 0 AIR carboxylase Peptidase_S51 PF03575.12 EPY52971.1 - 0.25 11.0 2.4 28 4.4 0.1 2.9 1 1 2 3 3 3 0 Peptidase family S51 Trypan_PARP PF05887.6 EPY52972.1 - 0.04 13.7 6.5 0.063 13.0 4.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Scm3 PF10384.4 EPY52973.1 - 9.4e-20 69.8 0.4 1.5e-19 69.2 0.2 1.3 1 0 0 1 1 1 1 Centromere protein Scm3 NTF2 PF02136.15 EPY52974.1 - 6.4e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EPY52974.1 - 0.0022 17.7 0.0 0.0052 16.5 0.0 1.6 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 PPTA PF01239.17 EPY52975.1 - 3.1e-43 143.3 21.9 2.4e-11 42.4 1.6 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.1 EPY52975.1 - 0.015 14.7 4.3 3.6 7.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) NifW PF03206.9 EPY52975.1 - 0.067 13.3 0.6 0.21 11.7 0.1 2.1 2 1 0 2 2 2 0 Nitrogen fixation protein NifW HA2 PF04408.18 EPY52977.1 - 6.5e-23 80.6 0.0 6.5e-23 80.6 0.0 2.9 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPY52977.1 - 6e-15 54.8 0.0 2.1e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPY52977.1 - 4.7e-12 45.7 0.1 2.8e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EPY52977.1 - 5.9e-08 32.3 0.1 1.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPY52977.1 - 0.0038 17.3 0.2 0.044 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EPY52977.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.9 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Ctr PF04145.10 EPY52978.1 - 8.7e-30 103.6 12.2 2.6e-29 102.1 8.4 1.7 1 1 0 1 1 1 1 Ctr copper transporter family LrgA PF03788.9 EPY52978.1 - 0.026 14.1 0.3 0.04 13.6 0.2 1.4 1 0 0 1 1 1 0 LrgA family PEN-2 PF10251.4 EPY52978.1 - 0.39 10.9 4.6 0.75 10.0 0.6 2.2 1 1 1 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase ArsA_ATPase PF02374.10 EPY52979.1 - 2.6e-111 371.5 0.2 2.9e-111 371.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EPY52979.1 - 2.3e-16 59.8 0.2 4e-16 59.0 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPY52979.1 - 2.1e-08 34.2 0.0 1.3e-07 31.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPY52979.1 - 8.4e-06 25.3 0.0 0.0012 18.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EPY52979.1 - 3.5e-05 23.1 0.1 7.3e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EPY52979.1 - 0.0012 18.2 0.3 0.0089 15.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPY52979.1 - 0.0098 14.7 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain PhoH PF02562.11 EPY52979.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein YhjQ PF06564.7 EPY52979.1 - 0.021 14.1 0.0 0.037 13.4 0.0 1.4 1 1 0 1 1 1 0 YhjQ protein MipZ PF09140.6 EPY52979.1 - 0.021 13.8 0.2 0.066 12.2 0.1 1.8 1 1 1 2 2 2 0 ATPase MipZ Zeta_toxin PF06414.7 EPY52979.1 - 0.052 12.6 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Gp37_Gp68 PF07505.6 EPY52979.1 - 0.093 11.8 0.1 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Phage protein Gp37/Gp68 IstB_IS21 PF01695.12 EPY52979.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Snf7 PF03357.16 EPY52980.1 - 6e-49 165.7 19.3 6e-49 165.7 13.4 1.3 1 1 0 1 1 1 1 Snf7 Hydant_A_N PF05378.8 EPY52980.1 - 0.014 14.9 1.0 0.027 13.9 0.7 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF2894 PF11445.3 EPY52980.1 - 2.6 8.2 9.0 4.9 7.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) Fork_head PF00250.13 EPY52981.1 - 1e-31 108.8 0.4 1.9e-31 107.9 0.3 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPY52981.1 - 3.8e-13 49.3 0.0 7.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain cNMP_binding PF00027.24 EPY52982.1 - 3.7e-42 142.0 0.2 4e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EPY52982.1 - 5.9e-06 25.6 0.5 2e-05 23.8 0.3 2.0 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.6 EPY52982.1 - 0.028 13.9 2.7 0.057 12.9 0.2 2.3 2 0 0 2 2 2 0 Cupin domain Tyr_Deacylase PF02580.11 EPY52984.1 - 2.7e-50 170.1 0.4 3e-50 169.9 0.3 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Sec16_C PF12931.2 EPY52984.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 PPR_3 PF13812.1 EPY52985.1 - 8.7e-09 34.9 1.2 4.3 7.8 0.0 8.2 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPY52985.1 - 1.2e-08 34.7 0.2 0.33 10.9 0.0 5.0 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.15 EPY52985.1 - 3.6e-05 23.4 0.3 8.6 6.5 0.0 6.2 6 0 0 6 6 6 1 PPR repeat rRNA_processing PF08524.6 EPY52986.1 - 3.2e-25 88.6 28.1 4e-25 88.3 19.5 1.1 1 0 0 1 1 1 1 rRNA processing Ndc1_Nup PF09531.5 EPY52986.1 - 7.1 4.9 5.8 7.2 4.9 4.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DKNYY PF13644.1 EPY52987.1 - 0.4 10.9 4.2 0.23 11.6 1.0 1.9 2 0 0 2 2 2 0 DKNYY family Ribosomal_S7 PF00177.16 EPY52988.1 - 1.5e-40 138.1 0.7 1.8e-40 137.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RRP14 PF15459.1 EPY52989.1 - 4.8e-16 58.5 1.0 4.8e-16 58.5 0.7 2.9 2 1 0 2 2 2 1 60S ribosome biogenesis protein Rrp14 DUF87 PF01935.12 EPY52989.1 - 0.3 10.8 7.1 0.38 10.5 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 HPIH PF13323.1 EPY52989.1 - 8 6.1 7.6 0.61 9.7 1.2 2.0 1 1 2 3 3 3 0 N-terminal domain with HPIH motif BolA PF01722.13 EPY52990.1 - 7.6e-21 73.8 0.0 9.7e-21 73.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Mito_carr PF00153.22 EPY52992.1 - 1.9e-65 216.6 4.3 2.3e-23 81.7 0.0 3.0 1 1 2 3 3 3 3 Mitochondrial carrier protein HSF_DNA-bind PF00447.12 EPY52993.1 - 2e-36 124.3 0.6 3.9e-36 123.3 0.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EPY52993.1 - 5e-19 68.3 0.1 8.5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Hexapep PF00132.19 EPY52994.1 - 1.3e-14 52.9 17.1 5e-06 25.7 1.0 4.4 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 EPY52994.1 - 8e-14 51.3 2.2 8e-14 51.3 1.5 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 EPY52994.1 - 1.4e-08 34.3 0.0 2.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EPY52994.1 - 1.2e-06 28.0 24.0 0.00022 20.7 2.9 3.9 1 1 3 4 4 4 4 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EPY52994.1 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain TLD PF07534.11 EPY52995.1 - 3.1e-28 98.5 0.1 3.8e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 TLD Proho_convert PF12177.3 EPY52995.1 - 0.12 11.9 0.8 0.37 10.4 0.2 2.1 2 0 0 2 2 2 0 Prohormone convertase enzyme ABC_membrane PF00664.18 EPY52996.1 - 8.9e-36 123.7 18.6 1.1e-35 123.3 12.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EPY52996.1 - 3.6e-34 118.0 0.0 1.5e-33 116.0 0.0 2.1 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 EPY52996.1 - 6.2e-08 32.9 0.7 0.0063 16.5 0.0 2.9 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EPY52996.1 - 9.2e-05 21.7 0.0 0.0063 15.7 0.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPY52996.1 - 9.8e-05 22.5 0.0 0.00081 19.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY52996.1 - 0.00016 21.7 0.0 0.00042 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EPY52996.1 - 0.0008 19.6 0.1 0.014 15.6 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPY52996.1 - 0.0022 17.1 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPY52996.1 - 0.0041 16.6 0.0 0.012 15.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EPY52996.1 - 0.0067 17.2 0.0 0.013 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EPY52996.1 - 0.011 15.6 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EPY52996.1 - 0.013 15.3 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPY52996.1 - 0.013 14.9 0.1 0.05 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 EPY52996.1 - 0.019 14.8 0.4 0.26 11.2 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EPY52996.1 - 0.023 14.4 0.0 0.18 11.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EPY52996.1 - 0.023 14.0 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPY52996.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EPY52996.1 - 0.037 13.7 0.0 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPY52996.1 - 0.045 13.4 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EPY52996.1 - 0.08 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPY52996.1 - 0.09 13.0 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain DASH_Spc34 PF08657.5 EPY52998.1 - 1.9e-24 86.7 14.9 6.4e-14 52.2 6.3 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Bacillus_HBL PF05791.6 EPY52998.1 - 0.029 13.7 1.1 0.052 12.9 0.8 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CitT PF12431.3 EPY52998.1 - 0.037 14.0 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 Transcriptional regulator DUF342 PF03961.8 EPY52998.1 - 0.081 11.3 3.6 0.082 11.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1640 PF07798.6 EPY52998.1 - 0.13 12.3 3.8 0.19 11.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TFIID_20kDa PF03847.8 EPY52999.1 - 6.7e-34 115.9 2.1 6.7e-34 115.9 1.5 1.8 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EPY52999.1 - 0.00018 21.4 0.1 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EPY52999.1 - 0.005 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EPY52999.1 - 0.016 15.2 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Macoilin PF09726.4 EPY52999.1 - 6.8 4.8 15.7 4.9 5.3 10.1 1.3 1 1 0 1 1 1 0 Transmembrane protein SNF2_N PF00176.18 EPY53000.1 - 2.5e-70 236.6 0.0 1.7e-69 233.8 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EPY53000.1 - 8.3e-45 152.9 12.1 7.6e-44 149.8 8.9 2.1 2 1 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EPY53000.1 - 1.2e-14 53.9 0.0 5e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPY53000.1 - 2.8e-06 26.3 0.0 2.8e-06 26.3 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EPY53000.1 - 0.00016 21.7 0.2 0.13 12.4 0.0 3.2 3 1 0 3 3 3 2 AAA domain zf-ZPR1 PF03367.8 EPY53001.1 - 1.2e-119 395.1 0.0 1.1e-59 200.2 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EPY53001.1 - 0.01 15.5 2.7 0.68 9.6 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 EPY53001.1 - 0.038 13.6 12.1 0.71 9.6 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 EPY53001.1 - 0.064 12.9 1.8 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EPY53001.1 - 0.11 11.7 8.3 1.9 7.8 1.5 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EPY53001.1 - 0.25 11.0 4.2 5 6.8 0.1 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 EPY53001.1 - 0.57 10.5 5.3 25 5.2 0.7 3.3 3 0 0 3 3 3 0 Restriction alleviation protein Lar CpXC PF14353.1 EPY53001.1 - 1.4 8.9 10.5 0.7 9.8 0.4 3.6 2 2 0 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.2 EPY53001.1 - 5.3 6.9 8.9 7 6.5 0.0 3.5 4 0 0 4 4 4 0 Transposase zinc-ribbon domain YjeF_N PF03853.10 EPY53002.1 - 2.1e-37 128.3 0.0 2.6e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Na_H_Exchanger PF00999.16 EPY53004.1 - 2.4e-76 256.7 38.8 3e-76 256.4 26.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FixQ PF05545.6 EPY53004.1 - 0.26 10.9 0.1 0.26 10.9 0.1 4.0 4 1 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ CH PF00307.26 EPY53006.1 - 1.3e-42 144.2 0.2 2.5e-23 82.1 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EPY53006.1 - 1.7e-13 49.9 0.3 1.3e-08 34.3 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.5 EPY53006.1 - 5.5e-08 32.6 0.1 4.7e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF759 PF05537.6 EPY53006.1 - 0.0015 17.3 0.1 1.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Borrelia burgdorferi protein of unknown function (DUF759) RasGAP_C PF03836.10 EPY53006.1 - 0.11 12.1 3.1 0.36 10.5 0.1 2.6 2 0 0 2 2 2 0 RasGAP C-terminus Seryl_tRNA_N PF02403.17 EPY53006.1 - 0.73 9.8 5.2 0.29 11.1 0.6 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.10 EPY53006.1 - 1.1 9.2 7.7 0.091 12.7 1.8 1.8 2 0 0 2 2 2 0 Fez1 IncA PF04156.9 EPY53006.1 - 4.1 6.9 12.3 0.49 9.9 2.6 2.8 1 1 1 2 2 2 0 IncA protein SUR7 PF06687.7 EPY53007.1 - 3.6e-31 108.3 13.0 5e-31 107.9 9.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family Prefoldin_2 PF01920.15 EPY53007.1 - 0.026 14.2 0.7 0.087 12.5 0.2 1.9 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 EPY53007.1 - 0.064 13.6 0.2 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF2207 PF09972.4 EPY53007.1 - 0.48 8.9 5.7 0.47 8.9 3.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2681 PF10883.3 EPY53007.1 - 2.9 8.1 4.9 29 4.9 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) NVEALA PF14055.1 EPY53007.1 - 2.9 7.6 5.6 5.9 6.6 0.3 2.8 2 0 0 2 2 2 0 NVEALA protein Muskelin_N PF06588.6 EPY53008.1 - 4.3e-69 232.1 2.8 4.6e-69 232.1 0.8 1.8 2 0 0 2 2 2 1 Muskelin N-terminus Kelch_3 PF13415.1 EPY53008.1 - 3.7e-21 74.7 0.1 2.6e-07 30.6 0.0 7.3 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EPY53008.1 - 3.1e-20 71.6 3.6 7.5e-07 28.8 0.1 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EPY53008.1 - 3.6e-13 49.1 0.7 0.00022 21.0 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 EPY53008.1 - 1.8e-12 46.8 10.1 2.7e-05 24.1 0.1 5.5 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EPY53008.1 - 1.9e-09 36.9 11.3 3.4e-05 23.4 0.1 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 EPY53008.1 - 2.5e-07 30.1 13.3 0.0069 15.9 0.0 5.4 5 0 0 5 5 5 2 Kelch motif zf-UBR PF02207.15 EPY53009.1 - 1.2e-18 66.6 9.9 1.2e-18 66.6 6.9 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EPY53009.1 - 1.2e-09 37.7 0.0 3.4e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UPF0547 PF10571.4 EPY53009.1 - 5.6 6.7 14.0 0.54 10.0 0.2 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Sedlin_N PF04628.8 EPY53010.1 - 6.9e-21 74.5 0.1 7.6e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase_Tyr PF07714.12 EPY53011.1 - 2.9e-08 33.1 0.0 7.7e-08 31.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EPY53011.1 - 4.5e-06 25.9 0.0 1.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain HEAT_2 PF13646.1 EPY53011.1 - 2.3e-05 24.5 0.3 0.0002 21.6 0.2 2.6 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EPY53011.1 - 0.00026 20.8 4.8 0.027 14.5 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EPY53011.1 - 0.024 15.1 4.8 2.4 8.7 0.0 4.3 4 1 1 5 5 5 0 HEAT-like repeat Ovate PF04844.8 EPY53011.1 - 0.092 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate Shugoshin_N PF07558.6 EPY53012.1 - 6.6e-11 41.7 8.2 2.3e-10 40.0 5.7 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EPY53012.1 - 4.7e-09 35.5 2.8 4.7e-09 35.5 1.9 2.5 2 0 0 2 2 2 1 Shugoshin C terminus AIP3 PF03915.8 EPY53013.1 - 1.1e-88 298.0 22.2 1.1e-88 298.0 15.4 3.0 3 0 0 3 3 3 1 Actin interacting protein 3 CorA PF01544.13 EPY53013.1 - 2.8 6.9 13.7 0.02 13.9 2.2 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF1761 PF08570.5 EPY53014.1 - 2.4e-21 76.0 0.9 2.9e-21 75.7 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Ribosomal_L44 PF00935.14 EPY53015.1 - 3.3e-32 110.2 10.7 4.6e-32 109.8 7.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.15 EPY53015.1 - 0.98 9.7 7.7 0.59 10.4 1.5 2.5 2 0 0 2 2 2 0 Ribosomal protein L33 Thymidylat_synt PF00303.14 EPY53016.1 - 7e-112 372.8 0.0 9.4e-112 372.3 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase Flavoprotein PF02441.14 EPY53016.1 - 8.2e-42 141.9 2.1 1.8e-41 140.8 1.4 1.6 1 0 0 1 1 1 1 Flavoprotein RXT2_N PF08595.6 EPY53016.1 - 0.0048 16.7 2.1 0.0088 15.8 1.4 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal Nop14 PF04147.7 EPY53016.1 - 0.09 10.6 7.9 0.12 10.2 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 EPY53016.1 - 0.31 11.0 6.8 0.52 10.3 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF605 PF04652.11 EPY53016.1 - 1.4 8.2 16.5 2 7.7 11.5 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 EPY53016.1 - 3 5.7 6.3 4.8 5.0 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein CTP_transf_2 PF01467.21 EPY53017.1 - 4.2e-16 59.3 0.0 8.1e-12 45.4 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase Metallophos_2 PF12850.2 EPY53018.1 - 9.3e-16 58.0 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPY53018.1 - 0.0022 17.3 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Acetyltransf_1 PF00583.19 EPY53020.1 - 1.1e-13 51.0 0.0 1.7e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPY53020.1 - 0.00051 20.1 0.0 0.0007 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY53020.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPY53020.1 - 0.0029 17.7 0.1 0.0053 16.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glutaredoxin PF00462.19 EPY53021.1 - 2.6e-16 59.3 0.0 3.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EPY53021.1 - 0.0039 17.3 0.1 0.0061 16.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 EPY53021.1 - 0.012 15.2 0.1 0.028 13.9 0.1 1.8 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF836 PF05768.9 EPY53021.1 - 0.026 14.7 0.0 0.035 14.3 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DUF1660 PF07874.6 EPY53021.1 - 0.079 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Prophage protein (DUF1660) Thioredoxin_3 PF13192.1 EPY53021.1 - 0.096 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain PI31_Prot_C PF08577.6 EPY53022.1 - 6.6e-10 39.5 6.2 6.6e-10 39.5 4.3 3.0 2 1 0 2 2 2 1 PI31 proteasome regulator GATase PF00117.23 EPY53023.1 - 7.1e-37 126.7 0.0 1.5e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EPY53023.1 - 3.1e-36 122.9 0.0 5.7e-36 122.1 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 EPY53023.1 - 1.1e-07 31.5 0.0 2.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 EPY53023.1 - 3e-06 26.3 0.0 0.00051 19.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 EPY53023.1 - 0.0011 18.2 0.0 0.018 14.2 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EPY53023.1 - 0.0029 16.7 0.1 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.11 EPY53023.1 - 0.0029 16.2 0.0 0.0054 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase MetJ PF01340.15 EPY53023.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 1 Met Apo-repressor, MetJ Asn_synthase PF00733.16 EPY53023.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EPY53023.1 - 0.041 13.3 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 PP-loop family DUF3139 PF11337.3 EPY53024.1 - 0.055 13.7 0.6 0.39 11.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) AMP-binding PF00501.23 EPY53025.1 - 1.4e-70 237.8 0.0 1.9e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPY53025.1 - 6e-67 225.1 0.0 1.1e-66 224.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EPY53025.1 - 3.4e-12 46.4 0.0 6.5e-11 42.3 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPY53025.1 - 1e-08 35.9 0.0 5.3e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EPY53025.1 - 1.5e-07 31.0 0.0 3.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY53025.1 - 0.00019 20.2 0.0 0.00037 19.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.15 EPY53025.1 - 0.0039 16.0 0.1 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain RmlD_sub_bind PF04321.12 EPY53025.1 - 0.2 10.4 0.1 8.7 5.1 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain Ribosomal_L16 PF00252.13 EPY53026.1 - 7.5e-32 109.8 0.2 9.4e-32 109.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e AA_permease PF00324.16 EPY53027.1 - 3.2e-141 470.9 40.1 3.6e-141 470.7 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPY53027.1 - 9.6e-42 142.9 45.8 1.3e-41 142.6 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease HSP20 PF00011.16 EPY53028.1 - 3.7e-22 78.1 0.4 4.4e-22 77.8 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 EPY53028.1 - 0.038 13.7 0.2 0.46 10.2 0.1 2.2 2 1 0 2 2 2 0 BON domain CS PF04969.11 EPY53028.1 - 0.043 14.3 0.2 0.092 13.2 0.1 1.7 1 1 0 1 1 1 0 CS domain Helicase_C PF00271.26 EPY53029.1 - 2.1e-10 40.2 0.0 3.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-UBR PF02207.15 EPY53029.1 - 0.094 12.4 0.3 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) RE_Bsp6I PF09504.5 EPY53029.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Ribonuc_L-PSP PF01042.16 EPY53030.1 - 5.8e-23 80.9 0.0 7e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 EPY53031.1 - 6e-27 94.2 36.6 6e-27 94.2 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY53031.1 - 7.1e-10 38.0 36.4 1.9e-09 36.6 25.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter HSP20 PF00011.16 EPY53032.1 - 6.3e-22 77.3 0.5 7.7e-22 77.0 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY53032.1 - 0.015 15.8 0.6 0.077 13.5 0.1 2.0 2 0 0 2 2 2 0 CS domain DUF4097 PF13349.1 EPY53032.1 - 0.025 14.1 0.2 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) PIH1 PF08190.7 EPY53032.1 - 0.058 12.8 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Epimerase PF01370.16 EPY53033.1 - 4.4e-11 42.6 0.0 1.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPY53033.1 - 1.7e-09 37.3 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPY53033.1 - 2.1e-08 34.3 0.0 2.8e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPY53033.1 - 8.3e-05 21.4 0.0 0.0045 15.7 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EPY53033.1 - 0.00049 20.0 0.0 0.00098 19.1 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EPY53033.1 - 0.0032 16.4 0.0 0.0045 15.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ApbA PF02558.11 EPY53033.1 - 0.0048 16.3 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EPY53033.1 - 0.041 13.7 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EPY53033.1 - 0.095 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MUG2_C PF08593.5 EPY53035.1 - 6.9e-07 29.4 0.4 2.2e-06 27.8 0.2 1.9 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal Mod_r PF07200.8 EPY53035.1 - 0.1 12.5 1.0 0.52 10.2 0.5 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MUG2_C PF08593.5 EPY53037.1 - 1.5e-11 44.3 0.0 2.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal NAD_binding_4 PF07993.7 EPY53040.1 - 1.6e-34 118.9 0.0 1.7e-33 115.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EPY53040.1 - 5e-10 38.3 0.3 4.3e-09 35.2 0.1 2.4 1 1 1 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EPY53040.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPY53040.1 - 0.033 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 EPY53040.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family But2 PF09792.4 EPY53041.1 - 2.4e-34 118.1 3.3 4.3e-34 117.3 2.3 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain RTA1 PF04479.8 EPY53042.1 - 1.8e-40 138.8 9.6 2.3e-40 138.4 6.7 1.1 1 0 0 1 1 1 1 RTA1 like protein NAD_binding_4 PF07993.7 EPY53044.1 - 3.3e-05 22.9 0.0 0.0015 17.5 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EPY53044.1 - 9.3e-05 21.9 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPY53044.1 - 0.0036 17.5 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF1886 PF09171.5 EPY53044.1 - 0.039 12.9 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) NAD_binding_10 PF13460.1 EPY53044.1 - 0.054 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EPY53044.1 - 0.068 11.8 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPY53044.1 - 0.2 11.5 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Flo11 PF10182.4 EPY53046.1 - 2.5e-33 114.8 0.5 7.7e-33 113.2 0.3 1.9 1 0 0 1 1 1 1 Flo11 domain Herpes_UL73 PF03554.8 EPY53048.1 - 0.26 11.1 3.0 0.82 9.5 0.3 2.1 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DUF1304 PF06993.7 EPY53049.1 - 0.031 14.0 2.2 0.052 13.2 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) Per1 PF04080.8 EPY53049.1 - 0.76 9.1 7.9 0.086 12.2 1.3 1.8 1 1 1 2 2 2 0 Per1-like Sec16 PF12932.2 EPY53050.1 - 6.1 6.8 13.8 0.96 9.4 0.5 3.2 2 1 1 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region Oxidored_FMN PF00724.15 EPY53052.1 - 3.3e-18 65.7 0.0 3.7e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3085 PF11284.3 EPY53052.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) Lactamase_B_2 PF12706.2 EPY53053.1 - 1.2e-19 70.6 0.2 1.3e-08 34.6 0.0 2.1 1 1 1 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPY53053.1 - 6.6e-06 25.9 0.0 0.00019 21.1 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPY53053.1 - 0.047 13.3 0.0 1.9 8.1 0.0 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Zn_clus PF00172.13 EPY53054.1 - 1.1e-06 28.4 12.5 2.4e-06 27.3 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IlvN PF07991.7 EPY53055.1 - 0.008 15.5 0.0 0.0086 15.4 0.0 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2OG-FeII_Oxy PF03171.15 EPY53055.1 - 0.022 15.0 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NmrA PF05368.8 EPY53056.1 - 1.4e-09 37.5 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPY53056.1 - 4.8e-08 33.2 0.0 6.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY53056.1 - 7.2e-06 25.5 0.1 1.8e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EPY53056.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EPY53056.1 - 0.0035 16.2 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPY53056.1 - 0.0057 15.3 0.1 0.0089 14.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.11 EPY53056.1 - 0.0062 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA WTF PF03303.8 EPY53058.1 - 0.39 10.1 13.2 1.4 8.3 9.2 2.0 1 1 0 1 1 1 0 WTF protein DUF3087 PF11286.3 EPY53058.1 - 0.64 9.2 2.9 0.4 9.9 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) FecCD PF01032.13 EPY53058.1 - 0.64 8.7 10.6 0.81 8.4 7.3 1.1 1 0 0 1 1 1 0 FecCD transport family XK-related PF09815.4 EPY53058.1 - 3.4 6.5 13.1 8.8 5.2 9.1 1.7 1 1 0 1 1 1 0 XK-related protein MFS_Mycoplasma PF07672.8 EPY53059.1 - 0.09 11.9 8.3 0.12 11.5 5.8 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF1129 PF06570.6 EPY53059.1 - 0.47 9.7 2.3 0.67 9.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2207 PF09972.4 EPY53059.1 - 1.9 7.0 4.4 2.5 6.5 3.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MRAP PF15183.1 EPY53059.1 - 3.9 7.1 7.3 9.1 5.9 5.1 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Ndc1_Nup PF09531.5 EPY53059.1 - 8.4 4.6 8.7 15 3.8 6.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HSP20 PF00011.16 EPY53060.1 - 9.8e-22 76.7 0.4 1.2e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY53060.1 - 0.025 15.1 0.2 0.11 13.0 0.1 1.9 1 1 1 2 2 2 0 CS domain DUF4097 PF13349.1 EPY53060.1 - 0.055 13.0 0.1 0.088 12.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) BON PF04972.12 EPY53060.1 - 0.069 12.9 0.2 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 BON domain PIH1 PF08190.7 EPY53060.1 - 0.089 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF1886 PF09171.5 EPY53061.1 - 0.0015 17.6 0.2 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1886) Spore_III_AB PF09548.5 EPY53061.1 - 0.084 12.6 0.2 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) But2 PF09792.4 EPY53062.1 - 1.3e-10 41.1 0.0 2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.11 EPY53063.1 - 5.7e-41 140.4 51.6 5.7e-41 140.4 35.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY53063.1 - 1.4e-10 40.3 16.9 1.4e-10 40.3 11.7 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter Guanylate_cyc PF00211.15 EPY53063.1 - 0.096 12.0 0.3 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain MUG2_C PF08593.5 EPY53068.1 - 3.6e-15 55.9 0.0 1.2e-14 54.2 0.0 2.0 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal DAP_B PF07930.7 EPY53068.1 - 0.076 12.7 0.2 0.17 11.6 0.1 1.7 1 1 0 1 1 1 0 D-aminopeptidase, domain B GPI-anchored PF10342.4 EPY53069.1 - 2.7e-11 43.7 2.6 3.6e-11 43.3 1.8 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FAD_binding_8 PF08022.7 EPY53072.1 - 3.8e-28 97.4 0.0 8.2e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPY53072.1 - 1.4e-21 76.9 2.3 2.6e-21 76.1 0.3 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPY53072.1 - 8.8e-11 41.9 7.0 1.4e-10 41.3 4.3 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EPY53072.1 - 3.6e-05 24.2 0.0 0.00051 20.5 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored_FMN PF00724.15 EPY53074.1 - 2.3e-109 365.5 0.0 2.6e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 EPY53076.1 - 2.3e-16 59.4 22.3 2.9e-16 59.1 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HMG_box PF00505.14 EPY53076.1 - 0.12 12.7 0.1 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box TFIIE-A_C-term PF11521.3 EPY53076.1 - 0.26 11.2 4.9 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha HSP20 PF00011.16 EPY53077.1 - 4.9e-22 77.7 0.5 6.1e-22 77.4 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY53077.1 - 0.023 15.2 0.5 0.05 14.1 0.1 1.7 2 0 0 2 2 2 0 CS domain DUF4097 PF13349.1 EPY53077.1 - 0.028 13.9 0.3 0.038 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Sugar_tr PF00083.19 EPY53078.1 - 4.1e-110 368.4 27.8 4.9e-110 368.2 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPY53078.1 - 9e-24 83.8 31.7 1.8e-19 69.7 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EPY53078.1 - 0.48 8.4 4.6 0.69 7.9 3.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector MUG2_C PF08593.5 EPY53079.1 - 9.4e-15 54.5 1.4 1.5e-14 53.9 0.0 2.1 3 0 0 3 3 3 1 Meiotically up-regulated glycoproteins C-terminal DUF4375 PF14300.1 EPY53079.1 - 0.0045 16.9 5.2 0.0072 16.3 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) Matrilin_ccoil PF10393.4 EPY53079.1 - 0.68 9.3 3.5 13 5.2 0.4 3.6 1 1 2 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin PaaSYMP PF14738.1 EPY53079.1 - 3 7.5 11.5 0.75 9.5 5.4 1.8 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Takusan PF04822.8 EPY53079.1 - 3.6 7.4 11.0 3.5 7.4 1.5 2.5 2 0 0 2 2 2 0 Takusan Asp PF00026.18 EPY53080.1 - 4.9e-19 68.7 1.7 8.4e-11 41.6 0.1 3.3 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPY53080.1 - 4.7e-06 26.6 0.2 0.00043 20.2 0.1 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EPY53080.1 - 0.00048 19.8 0.0 0.72 9.7 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EPY53080.1 - 0.00072 20.0 0.2 1.4 9.5 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EPY53080.1 - 0.032 14.1 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease Hemerythrin PF01814.18 EPY53082.1 - 2.9e-12 46.9 0.0 4.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain FAD_binding_7 PF03441.9 EPY53082.1 - 0.028 13.6 0.1 0.32 10.1 0.0 2.0 1 1 1 2 2 2 0 FAD binding domain of DNA photolyase M-factor PF03855.8 EPY53083.1 - 0.00065 19.6 7.7 0.001 18.9 5.3 1.4 1 1 0 1 1 1 1 M-factor DUF2424 PF10340.4 EPY53084.1 - 6.3e-66 222.5 0.5 7.2e-66 222.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EPY53084.1 - 6.5e-18 65.0 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EPY53084.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EPY53084.1 - 0.038 13.8 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY53084.1 - 0.063 13.0 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY53084.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DJ-1_PfpI PF01965.19 EPY53085.1 - 1.6e-29 102.2 0.2 2.5e-29 101.6 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPY53085.1 - 0.0021 17.5 0.2 0.0076 15.7 0.2 2.0 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family PCMT PF01135.14 EPY53086.1 - 9.1e-66 221.3 0.0 1.1e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EPY53086.1 - 1.3e-09 38.6 0.0 2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY53086.1 - 5.3e-06 26.0 0.0 1.2e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY53086.1 - 2.4e-05 24.3 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPY53086.1 - 4.2e-05 22.7 0.0 5.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EPY53086.1 - 6e-05 22.2 0.0 7.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EPY53086.1 - 6.4e-05 23.3 0.0 0.00013 22.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY53086.1 - 6.5e-05 22.7 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY53086.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.5 EPY53086.1 - 0.00021 20.8 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Fibrillarin PF01269.12 EPY53086.1 - 0.005 15.8 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin RrnaAD PF00398.15 EPY53086.1 - 0.0059 15.6 0.0 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 EPY53086.1 - 0.007 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPY53086.1 - 0.0072 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EPY53086.1 - 0.011 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EPY53086.1 - 0.017 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.7 EPY53086.1 - 0.032 13.6 0.1 0.053 12.8 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.8 EPY53086.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DIOX_N PF14226.1 EPY53087.1 - 1.1e-15 58.2 0.0 2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPY53087.1 - 2.5e-15 56.5 0.0 4.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mac PF12464.3 EPY53088.1 - 7.6e-10 38.6 0.1 1e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EPY53088.1 - 0.0028 17.1 0.4 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EPY53088.1 - 0.004 16.6 0.2 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) Hexapep PF00132.19 EPY53089.1 - 3.2e-13 48.5 10.6 1.4e-09 37.0 3.1 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPY53089.1 - 1.4e-12 46.9 11.3 1.2e-09 37.5 3.1 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EPY53089.1 - 1.8e-09 37.4 0.1 2.6e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase MFS_1 PF07690.11 EPY53090.1 - 8.8e-37 126.6 32.5 8.8e-37 126.6 22.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY53090.1 - 1.1e-12 47.2 12.4 1.1e-12 47.2 8.6 2.6 1 1 2 3 3 3 1 Sugar (and other) transporter DUF912 PF06024.7 EPY53090.1 - 0.33 11.0 1.5 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3185 PF11381.3 EPY53090.1 - 0.36 10.6 7.8 0.036 13.8 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) dCMP_cyt_deam_1 PF00383.17 EPY53091.1 - 2.4e-22 78.4 0.0 3.2e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EPY53091.1 - 5.5e-05 22.8 0.0 0.00019 21.1 0.0 1.8 2 0 0 2 2 2 1 APOBEC-like N-terminal domain OTT_1508_deam PF14441.1 EPY53091.1 - 0.0072 16.1 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase Toxin-deaminase PF14424.1 EPY53091.1 - 0.12 12.3 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Bd3614-deam PF14439.1 EPY53091.1 - 0.23 11.3 1.1 2.4 8.0 0.7 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase CN_hydrolase PF00795.17 EPY53092.1 - 5.9e-36 123.5 0.0 7.4e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RTA1 PF04479.8 EPY53093.1 - 3e-62 210.0 0.2 3e-62 210.0 0.1 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF202 PF02656.10 EPY53093.1 - 0.84 9.8 7.9 5.7 7.2 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Amastin PF07344.6 EPY53093.1 - 9.6 5.8 10.9 34 4.0 7.6 2.2 1 1 0 1 1 1 0 Amastin surface glycoprotein SLAC1 PF03595.12 EPY53095.1 - 4.2e-69 232.7 48.0 4.7e-69 232.5 33.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MUG2_C PF08593.5 EPY53099.1 - 2.5e-09 37.2 0.6 7.1e-09 35.7 0.4 1.8 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal CHASE3 PF05227.8 EPY53099.1 - 0.0056 16.3 2.0 0.0078 15.9 0.9 1.6 2 0 0 2 2 2 1 CHASE3 domain EcoR124_C PF12008.3 EPY53099.1 - 0.032 13.4 0.1 0.79 8.8 0.1 2.2 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Mod_r PF07200.8 EPY53099.1 - 0.048 13.5 0.3 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2675 PF11247.3 EPY53101.1 - 0.11 12.5 0.1 11 6.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2675) DUF106 PF01956.11 EPY53102.1 - 3.2e-53 179.7 2.8 4.1e-53 179.3 1.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 THF_DHG_CYH PF00763.18 EPY53103.1 - 4.5e-21 75.0 0.0 1e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EPY53103.1 - 1.4e-14 53.4 0.0 2e-10 39.9 0.0 3.2 2 1 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TAFH PF07531.9 EPY53103.1 - 0.039 13.6 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 NHR1 homology to TAF SBP_bac_5 PF00496.17 EPY53103.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle SRP40_C PF05022.7 EPY53104.1 - 1.5e-26 92.6 3.0 1.5e-26 92.6 2.1 2.5 3 0 0 3 3 3 1 SRP40, C-terminal domain LisH PF08513.6 EPY53104.1 - 2.7e-06 26.9 0.1 5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 LisH DUF1041 PF06292.12 EPY53104.1 - 4 7.6 5.7 0.73 10.0 0.1 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1041) Ribosomal_L4 PF00573.17 EPY53105.1 - 8.3e-45 152.5 1.3 1.2e-44 152.0 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EPY53105.1 - 1.3e-27 95.4 2.9 1.3e-27 95.4 2.0 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Hyphal_reg_CWP PF11765.3 EPY53108.1 - 1.8e-22 79.5 5.3 3e-22 78.8 3.7 1.4 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal CDK2AP PF09806.4 EPY53109.1 - 0.06 13.5 0.5 0.083 13.1 0.4 1.2 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MAGE_N PF12440.3 EPY53109.1 - 7.6 6.8 10.4 1.8 8.9 4.8 1.8 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Zn_clus PF00172.13 EPY53110.1 - 6.2e-08 32.4 15.7 1.7e-07 30.9 10.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EPY53111.1 - 2.8e-50 170.9 6.3 2.8e-50 170.9 4.4 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF1218 PF06749.7 EPY53111.1 - 2.4 8.6 7.9 2 8.9 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) HisK_N PF09385.5 EPY53112.1 - 0.021 14.4 0.3 0.05 13.2 0.2 1.7 1 0 0 1 1 1 0 Histidine kinase N terminal EF-hand_4 PF12763.2 EPY53113.1 - 1.3e-35 121.2 0.0 5.7e-11 42.0 0.0 3.8 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EPY53113.1 - 1.9e-12 47.0 0.0 9.7e-05 22.4 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EPY53113.1 - 9.9e-09 33.8 0.1 0.15 11.4 0.0 5.3 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 EPY53113.1 - 4.1e-05 23.1 0.2 12 6.0 0.0 5.1 5 0 0 5 5 5 1 EF-hand domain EF-hand_8 PF13833.1 EPY53113.1 - 0.0029 17.1 0.3 0.43 10.2 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain pair DUF960 PF06124.6 EPY53113.1 - 0.11 12.7 5.4 12 6.2 0.0 4.7 6 0 0 6 6 6 0 Staphylococcal protein of unknown function (DUF960) TPR_MLP1_2 PF07926.7 EPY53113.1 - 0.49 10.1 38.9 0.37 10.5 15.3 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EPY53113.1 - 7.2 5.6 20.7 2.6 7.1 8.9 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EPY53113.1 - 8.6 5.2 23.4 1.2 7.9 12.7 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EPY53113.1 - 8.9 6.1 34.9 3.5 7.5 14.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ubiquitin PF00240.18 EPY53114.1 - 5.1e-07 28.9 0.0 8.8e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPY53114.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CENP-T PF15511.1 EPY53115.1 - 1.6e-24 86.9 33.1 1.1e-23 84.2 23.0 2.0 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EPY53115.1 - 3.5e-11 43.1 0.2 8.8e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EPY53115.1 - 2.1e-09 37.3 0.1 4.5e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EPY53115.1 - 0.00012 21.6 0.0 0.00034 20.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EPY53115.1 - 0.00015 21.7 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EPY53115.1 - 0.006 16.3 0.2 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit TFIID_20kDa PF03847.8 EPY53115.1 - 0.054 13.7 0.3 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Striatin PF08232.7 EPY53116.1 - 1.3e-23 83.7 9.1 1.3e-23 83.7 6.3 2.8 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 EPY53116.1 - 3e-16 58.5 0.6 2.1e-07 30.5 0.3 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPY53116.1 - 0.0078 15.9 0.0 0.8 9.5 0.0 3.1 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region DUF2533 PF10752.4 EPY53116.1 - 0.07 13.4 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) DUF2430 PF10353.4 EPY53117.1 - 3.1e-08 33.7 0.1 5.2e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2430) AhpC-TSA PF00578.16 EPY53118.1 - 9.4e-26 89.9 0.0 1.2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPY53118.1 - 8.2e-17 61.1 0.0 1.1e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EPY53118.1 - 0.00033 20.5 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme CDC50 PF03381.10 EPY53119.1 - 1.8e-100 335.6 0.1 2.3e-100 335.3 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family tRNA-synt_2 PF00152.15 EPY53120.1 - 1.2e-74 251.1 0.1 1.7e-74 250.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPY53120.1 - 1.6e-11 43.8 0.0 3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DnaJ PF00226.26 EPY53121.1 - 4.2e-22 77.6 2.5 8.2e-22 76.7 1.8 1.5 1 0 0 1 1 1 1 DnaJ domain Glyco_transf_15 PF01793.11 EPY53122.1 - 2e-123 411.5 13.5 2.6e-123 411.1 9.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ran_BP1 PF00638.13 EPY53123.1 - 5.8e-49 165.2 0.8 5.8e-49 165.2 0.5 1.5 2 0 0 2 2 2 1 RanBP1 domain VID27 PF08553.5 EPY53123.1 - 0.046 11.9 9.1 0.052 11.7 6.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DHHW PF14286.1 EPY53123.1 - 9.6 5.3 9.4 12 5.0 6.5 1.1 1 0 0 1 1 1 0 DHHW protein ADH_zinc_N PF00107.21 EPY53124.1 - 2e-24 85.6 0.1 3e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPY53124.1 - 1.6e-14 53.5 0.0 7.5e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPY53124.1 - 3.3e-12 47.4 0.0 7.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EPY53124.1 - 0.014 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EPY53124.1 - 0.06 12.9 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.7 EPY53125.1 - 1.5e-32 111.6 0.3 3.7e-32 110.3 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPY53125.1 - 5e-18 64.9 0.1 9.7e-18 63.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EPY53125.1 - 1.4e-05 25.6 0.1 2.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPY53125.1 - 6.1e-05 23.9 0.0 0.00013 22.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EPY53125.1 - 0.0027 17.3 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EPY53125.1 - 0.0058 16.2 0.5 0.019 14.5 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EPY53125.1 - 0.0059 16.5 0.0 0.0091 15.9 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_11 PF08241.7 EPY53125.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPY53125.1 - 0.02 14.8 0.1 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EPY53125.1 - 0.024 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.9 EPY53125.1 - 0.036 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DapB_N PF01113.15 EPY53125.1 - 0.041 13.8 0.1 0.1 12.4 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_12 PF08242.7 EPY53125.1 - 0.042 14.3 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EPY53125.1 - 0.063 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CMAS PF02353.15 EPY53125.1 - 0.079 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EPY53125.1 - 0.11 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EPY53126.1 - 7.6e-19 68.0 0.0 2.2e-18 66.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY53126.1 - 1.3e-15 56.8 0.0 2.1e-15 56.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPY53126.1 - 1.2e-08 34.1 1.1 2.1e-05 23.6 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.1 EPY53126.1 - 4.4e-07 30.0 0.0 8.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPY53126.1 - 6.2e-07 28.6 0.0 9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EPY53126.1 - 0.00052 19.3 0.0 0.0042 16.3 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPY53126.1 - 0.0065 16.3 0.2 0.043 13.7 0.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPY53126.1 - 0.064 12.9 0.0 8.9 5.9 0.0 2.5 3 0 0 3 3 3 0 KR domain Aminotran_3 PF00202.16 EPY53127.1 - 5.4e-83 278.6 0.0 6.3e-83 278.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Iron_permease PF04120.7 EPY53128.1 - 1.5e-37 128.1 21.3 3.5e-12 46.0 1.1 4.2 3 1 1 4 4 4 4 Low affinity iron permease MalF_P2 PF14785.1 EPY53128.1 - 0.027 14.3 0.0 0.091 12.6 0.0 1.8 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain GTP_EFTU PF00009.22 EPY53129.1 - 9.2e-38 129.5 2.2 5.5e-37 127.0 1.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPY53129.1 - 2.9e-26 91.4 0.0 6.9e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPY53129.1 - 1.3e-11 44.4 0.3 6.6e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPY53129.1 - 1.4e-08 34.7 0.1 3.2e-08 33.5 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPY53129.1 - 2e-06 28.2 0.1 4.5e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EPY53129.1 - 4.2e-06 26.3 0.5 1.4e-05 24.6 0.4 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation IF2_N PF04760.10 EPY53129.1 - 1.2e-05 24.8 0.0 0.00036 20.1 0.0 2.6 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.13 EPY53129.1 - 0.00013 21.3 0.1 0.00091 18.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 EPY53129.1 - 0.00038 19.8 0.0 0.00081 18.8 0.0 1.5 1 0 0 1 1 1 1 Ras family ArgK PF03308.11 EPY53129.1 - 0.00051 18.9 1.2 0.0065 15.2 0.8 2.1 1 1 1 2 2 2 1 ArgK protein SRPRB PF09439.5 EPY53129.1 - 0.0067 15.6 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EPY53129.1 - 0.019 14.7 1.8 0.32 10.8 0.0 2.6 2 1 1 3 3 3 0 Dynamin family AAA_29 PF13555.1 EPY53129.1 - 0.095 12.2 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EPY53129.1 - 0.12 11.5 0.0 0.48 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 GTP_EFTU_D4 PF14578.1 EPY53129.1 - 0.39 10.3 4.0 1.2 8.8 0.1 2.7 3 0 0 3 3 3 0 Elongation factor Tu domain 4 ArgJ PF01960.13 EPY53130.1 - 7.3e-139 462.4 6.9 8.3e-139 462.2 4.8 1.0 1 0 0 1 1 1 1 ArgJ family ABC_sub_bind PF04392.7 EPY53130.1 - 0.027 13.4 0.1 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter substrate binding protein Ribosomal_L17 PF01196.14 EPY53132.1 - 1e-30 106.1 0.4 1.6e-30 105.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 DUF241 PF03087.9 EPY53132.1 - 0.12 11.9 2.0 6 6.2 0.0 2.2 2 0 0 2 2 2 0 Arabidopsis protein of unknown function Oxysterol_BP PF01237.13 EPY53133.1 - 1.8e-83 279.9 0.3 2.4e-83 279.5 0.2 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Mito_carr PF00153.22 EPY53134.1 - 4e-33 113.0 9.0 1.2e-13 50.5 0.0 4.6 2 1 1 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 EPY53135.1 - 7e-32 110.4 20.0 7e-32 110.4 13.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY53136.1 - 6.1e-23 81.1 37.5 4e-19 68.5 7.8 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPY53136.1 - 2.1e-17 62.8 44.8 6.2e-13 48.1 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-AN1 PF01428.11 EPY53138.1 - 8e-10 38.4 8.9 1.5e-09 37.6 6.2 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.18 EPY53138.1 - 0.0025 17.1 0.0 0.0099 15.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPY53138.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DS PF01916.12 EPY53139.1 - 2.5e-144 479.9 0.0 2.9e-144 479.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase NIF PF03031.13 EPY53140.1 - 1.7e-24 86.3 0.4 2.6e-24 85.6 0.2 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Methyltransf_12 PF08242.7 EPY53140.1 - 0.12 12.8 0.6 0.25 11.8 0.4 1.5 1 0 0 1 1 1 0 Methyltransferase domain STT3 PF02516.9 EPY53141.1 - 1.3e-146 489.3 40.2 4.6e-142 474.3 24.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Clr5 PF14420.1 EPY53142.1 - 2.7e-08 33.5 0.2 5.1e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain EST1 PF10374.4 EPY53142.1 - 0.065 13.2 0.2 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 Sec16_C PF12931.2 EPY53143.1 - 1.6e-67 228.2 1.0 2.8e-67 227.4 0.7 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EPY53143.1 - 9.4e-19 67.5 0.0 4.1e-18 65.4 0.0 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Rcd1 PF04078.8 EPY53144.1 - 2.1e-130 433.2 1.3 2.4e-130 433.0 0.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Methyltransf_26 PF13659.1 EPY53145.1 - 1.7e-07 31.3 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY53145.1 - 2.9e-07 30.0 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EPY53145.1 - 0.00042 19.9 0.0 0.00085 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY53145.1 - 0.00097 19.4 0.0 0.01 16.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY53145.1 - 0.039 14.4 0.5 2.3 8.7 0.1 2.9 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 EPY53145.1 - 0.049 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.10 EPY53145.1 - 0.059 12.7 0.0 0.28 10.5 0.0 2.0 3 0 0 3 3 3 0 Conserved hypothetical protein 95 HATPase_c_4 PF13749.1 EPY53145.1 - 0.082 12.6 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 ATP-dependent DNA helicase recG C-terminal Methyltransf_18 PF12847.2 EPY53145.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SOR_SNZ PF01680.12 EPY53146.1 - 8.7e-115 381.5 4.0 1.5e-114 380.7 2.8 1.4 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EPY53146.1 - 8.6e-08 31.5 3.8 2e-06 27.0 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EPY53146.1 - 0.00031 19.7 0.2 0.14 10.9 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EPY53146.1 - 0.0067 15.7 0.3 0.11 11.7 0.0 2.4 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 EPY53146.1 - 0.023 13.6 1.3 0.43 9.5 0.0 2.6 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EPY53146.1 - 0.03 13.4 0.2 0.03 13.4 0.2 2.3 2 1 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.16 EPY53146.1 - 0.058 12.4 0.0 0.55 9.2 0.0 2.3 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF2267 PF10025.4 EPY53146.1 - 0.062 13.3 0.0 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) RNR_inhib PF08591.5 EPY53147.1 - 4.3e-10 40.3 0.1 7.6e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Flu_B_NS1 PF02942.9 EPY53147.1 - 0.027 13.3 0.1 0.042 12.7 0.1 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) SET PF00856.23 EPY53148.1 - 6.5e-21 75.3 0.2 6.5e-21 75.3 0.2 4.3 3 2 0 3 3 3 2 SET domain SRI PF08236.6 EPY53148.1 - 2.1e-15 56.3 0.9 2.1e-15 56.3 0.6 2.9 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EPY53148.1 - 0.0007 19.0 0.1 0.0016 17.8 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SNF2_N PF00176.18 EPY53149.1 - 8.6e-71 238.1 4.7 8.6e-71 238.1 3.3 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EPY53149.1 - 1e-49 168.2 24.4 1e-49 168.2 16.9 3.5 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 EPY53149.1 - 1.5e-13 50.3 0.0 3.7e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EPY53150.1 - 1.7e-57 194.0 0.0 5.3e-57 192.3 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EPY53150.1 - 2.5e-51 173.5 1.6 2.5e-51 173.5 1.1 1.7 2 0 0 2 2 2 1 DEAD_2 Vps51 PF08700.6 EPY53151.1 - 7.8e-19 67.3 2.6 1.2e-18 66.7 1.8 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EPY53151.1 - 0.021 13.3 2.1 0.025 13.0 1.4 1.1 1 0 0 1 1 1 0 Dor1-like family Baculo_PEP_C PF04513.7 EPY53151.1 - 0.028 14.2 1.0 0.04 13.7 0.7 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EPY53151.1 - 0.031 14.1 1.8 0.042 13.7 1.2 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EPY53151.1 - 0.038 13.7 0.9 0.066 12.9 0.6 1.4 1 0 0 1 1 1 0 Laminin Domain II Lyase_1 PF00206.15 EPY53151.1 - 0.076 12.1 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Lyase COG5 PF10392.4 EPY53151.1 - 0.08 12.8 3.2 0.11 12.4 2.2 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Glyco_transf_20 PF00982.16 EPY53152.1 - 8.8e-145 482.7 3.9 1e-144 482.6 0.7 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPY53152.1 - 1.7e-69 233.3 0.0 2.7e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EPY53152.1 - 1.4e-06 28.1 0.0 0.0031 17.1 0.0 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPY53152.1 - 0.046 13.6 0.0 0.19 11.6 0.0 2.1 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Evr1_Alr PF04777.8 EPY53153.1 - 3.8e-28 97.2 1.9 3.8e-28 97.2 1.3 1.9 2 0 0 2 2 2 1 Erv1 / Alr family XPG_N PF00752.12 EPY53154.1 - 4.1e-38 129.6 0.0 7.2e-38 128.9 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPY53154.1 - 2.7e-29 101.0 0.1 4.9e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EPY53154.1 - 3e-06 27.4 0.0 9.9e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 EPY53154.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF4142 PF13628.1 EPY53154.1 - 0.19 11.7 2.0 0.4 10.7 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Mpv17_PMP22 PF04117.7 EPY53155.1 - 6.5e-24 83.3 0.9 6.5e-24 83.3 0.6 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family YdfZ PF14001.1 EPY53155.1 - 0.035 14.3 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 YdfZ protein RRM_1 PF00076.17 EPY53156.1 - 1.8e-25 88.3 0.1 2e-16 59.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53156.1 - 6.3e-24 83.7 0.1 3.6e-14 52.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53156.1 - 3.1e-08 33.3 0.0 0.0077 16.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PINIT PF14324.1 EPY53156.1 - 0.0076 16.3 0.1 0.016 15.3 0.1 1.5 1 1 0 1 1 1 1 PINIT domain Maf PF02545.9 EPY53157.1 - 7.6e-50 168.7 0.0 9.5e-50 168.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DSS1_SEM1 PF05160.8 EPY53158.1 - 8.6e-21 73.4 14.6 9.1e-21 73.4 10.1 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family DUF4624 PF15417.1 EPY53158.1 - 0.062 12.9 2.3 0.11 12.0 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4624) YL1 PF05764.8 EPY53158.1 - 0.26 10.8 3.3 0.27 10.8 2.3 1.0 1 0 0 1 1 1 0 YL1 nuclear protein DUF2947 PF11163.3 EPY53158.1 - 0.58 9.7 4.2 0.64 9.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) SNF2_N PF00176.18 EPY53159.1 - 3.4e-71 239.4 0.9 3.4e-71 239.4 0.6 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EPY53159.1 - 3.4e-27 94.6 2.3 5.5e-27 93.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EPY53159.1 - 1.2e-23 82.5 2.0 3.4e-12 45.8 0.5 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EPY53159.1 - 3.7e-13 49.1 0.0 2.3e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY53159.1 - 1.5e-06 28.1 0.0 1.5e-06 28.1 0.0 2.9 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.6 EPY53159.1 - 0.0017 18.1 0.1 0.0098 15.6 0.0 2.3 3 0 0 3 3 3 1 CHDCT2 (NUC038) domain FF PF01846.14 EPY53160.1 - 4.2e-46 154.6 14.5 7.2e-14 51.4 0.2 5.7 5 0 0 5 5 5 5 FF domain WW PF00397.21 EPY53160.1 - 1.3e-16 60.1 12.1 4.7e-09 35.9 1.2 2.9 2 0 0 2 2 2 2 WW domain DUF4105 PF13387.1 EPY53160.1 - 0.022 13.9 1.7 0.079 12.1 1.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) DUF1746 PF08508.5 EPY53161.1 - 1.1e-26 93.0 7.7 1.6e-26 92.5 5.3 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) AmoA PF05145.7 EPY53161.1 - 0.039 13.0 2.9 0.052 12.5 2.0 1.1 1 0 0 1 1 1 0 Putative ammonia monooxygenase ATP_bind_1 PF03029.12 EPY53162.1 - 5.1e-85 284.8 0.0 5.8e-85 284.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MobB PF03205.9 EPY53162.1 - 0.018 14.7 0.0 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PPV_E1_C PF00519.12 EPY53162.1 - 0.088 11.3 0.1 0.94 8.0 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase CbiA PF01656.18 EPY53162.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 EPY53162.1 - 0.16 11.3 0.1 19 4.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF2733 PF10813.3 EPY53163.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) Spt20 PF12090.3 EPY53164.1 - 4.4e-44 150.0 1.1 4.4e-44 150.0 0.8 2.5 3 0 0 3 3 3 2 Spt20 family NTP_transferase PF00483.18 EPY53165.1 - 5e-12 45.6 0.0 3e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EPY53165.1 - 3.4e-05 23.9 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EPY53165.1 - 0.00012 21.4 13.5 0.06 12.8 0.2 3.7 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPY53165.1 - 0.033 13.7 11.7 0.31 10.6 0.2 3.8 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase GATase_2 PF00310.16 EPY53167.1 - 5.5e-27 94.4 0.0 1.2e-20 73.5 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPY53167.1 - 1e-14 54.5 0.0 2.4e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPY53167.1 - 6.3e-14 51.7 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EPY53167.1 - 9.3e-10 38.3 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EPY53167.1 - 9.4e-05 21.2 0.0 0.00015 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Sad1_UNC PF07738.8 EPY53168.1 - 4.2e-08 33.0 0.4 6.2e-07 29.2 0.1 2.6 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal DUF4187 PF13821.1 EPY53168.1 - 1.3 8.7 4.1 2.8 7.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) NAD_binding_7 PF13241.1 EPY53169.1 - 5.6e-29 100.4 0.0 7.9e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPY53169.1 - 2.3e-19 68.4 0.0 3.9e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EPY53169.1 - 1.2e-13 49.7 0.6 2.1e-13 48.9 0.1 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Enterotoxin_HS1 PF08090.6 EPY53169.1 - 0.045 13.4 0.1 0.09 12.5 0.1 1.4 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 WD40 PF00400.27 EPY53170.1 - 4.7e-33 111.8 0.5 4.4e-09 35.8 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EPY53170.1 - 1.9e-05 24.2 1.5 0.11 11.8 0.1 2.2 2 0 0 2 2 2 2 PQQ-like domain Big_3_3 PF13750.1 EPY53170.1 - 0.02 14.3 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Prenyltransf PF01255.14 EPY53171.1 - 2.7e-82 275.2 0.1 3.1e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase WD40 PF00400.27 EPY53172.1 - 9.9e-53 174.2 15.9 1.6e-11 43.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EPY53172.1 - 2.6e-07 29.1 10.0 0.027 12.6 0.3 5.6 2 2 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EPY53172.1 - 0.0001 21.8 0.6 0.025 14.0 0.0 2.4 2 1 0 2 2 2 2 PQQ-like domain F-box-like PF12937.2 EPY53172.1 - 0.00054 19.6 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPY53172.1 - 0.0015 18.1 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Ricin_B_lectin PF00652.17 EPY53172.1 - 0.013 15.5 0.1 0.037 14.0 0.0 1.9 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Birna_VP4 PF01768.11 EPY53173.1 - 0.022 13.8 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Birnavirus VP4 protein GDPD PF03009.12 EPY53174.1 - 1.3e-35 123.1 0.0 1.9e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EPY53174.1 - 0.0018 18.3 0.0 0.056 13.6 0.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Sec7 PF01369.15 EPY53175.1 - 1.4e-65 220.5 0.4 5.3e-65 218.6 0.2 2.1 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EPY53175.1 - 1.3e-52 177.6 4.6 1.3e-52 177.6 3.2 4.1 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPY53175.1 - 1.1e-26 92.0 1.4 1.1e-26 92.0 1.0 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) SLS PF14611.1 EPY53176.1 - 6.7e-21 74.6 5.1 9.5e-21 74.1 0.4 2.3 2 0 0 2 2 2 2 Mitochondrial inner-membrane-bound regulator Vac_ImportDeg PF09783.4 EPY53177.1 - 3.2e-37 127.7 0.0 4.9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Peptidase_S8 PF00082.17 EPY53178.1 - 6.5e-52 176.4 0.4 9.7e-52 175.8 0.3 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.3 EPY53178.1 - 1.3e-49 168.1 0.5 2.6e-49 167.1 0.3 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II GTP1_OBG PF01018.17 EPY53179.1 - 2.4e-35 121.5 3.7 9.5e-24 83.8 0.9 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EPY53179.1 - 5e-22 78.0 0.0 1.1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY53179.1 - 2.9e-09 36.3 0.0 2.3e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPY53179.1 - 8.1e-06 25.3 0.1 0.053 12.9 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Arf PF00025.16 EPY53179.1 - 1.4e-05 24.3 0.0 4.3e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPY53179.1 - 0.00019 21.9 0.0 0.0062 17.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EPY53179.1 - 0.00069 18.8 0.0 0.0031 16.7 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EPY53179.1 - 0.0031 16.3 0.2 0.14 10.8 0.0 2.2 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 EPY53179.1 - 0.016 15.0 0.0 0.36 10.6 0.0 2.7 2 1 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 EPY53179.1 - 0.017 14.6 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EPY53179.1 - 0.03 13.7 0.4 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.17 EPY53179.1 - 0.038 13.3 0.0 0.2 11.0 0.0 2.0 1 1 0 1 1 1 0 Ras family ABC_tran PF00005.22 EPY53179.1 - 0.039 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EPY53179.1 - 0.042 13.3 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_C PF08438.5 EPY53179.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal PRELI PF04707.9 EPY53180.1 - 4.6e-47 159.4 0.0 5.3e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family HEAT PF02985.17 EPY53181.1 - 4.3e-44 144.6 22.7 0.00067 19.5 0.0 13.9 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EPY53181.1 - 1.3e-33 115.1 1.2 3.8e-09 36.7 0.0 6.7 4 2 2 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 EPY53181.1 - 1.8e-13 50.5 11.8 1.3 9.5 0.3 9.5 7 2 3 10 10 10 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPY53181.1 - 1.8e-12 47.4 3.0 0.095 13.1 0.0 7.4 3 2 5 8 8 8 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPY53181.1 - 1.2e-06 27.2 1.5 1.9e-05 23.2 0.1 2.9 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.2 EPY53181.1 - 0.00057 19.7 4.0 0.61 9.9 0.0 5.0 2 2 3 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EPY53181.1 - 0.002 17.8 10.6 5.8 6.9 0.0 7.1 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat M11L PF11099.3 EPY53181.1 - 0.12 12.0 0.2 7.3 6.2 0.0 3.3 2 1 0 3 3 3 0 Apoptosis regulator M11L like EF-hand_7 PF13499.1 EPY53182.1 - 5.5e-12 45.6 0.0 6e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPY53182.1 - 7.8e-11 40.9 0.0 0.00041 20.0 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EPY53182.1 - 3.3e-10 38.5 0.2 0.0013 17.8 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EPY53182.1 - 1.9e-07 30.8 0.0 0.001 18.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EPY53182.1 - 0.00019 21.0 0.6 0.0052 16.3 0.1 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EPY53182.1 - 0.011 15.0 0.1 0.62 9.5 0.0 3.1 3 1 0 3 3 3 0 EF hand DAHP_synth_1 PF00793.15 EPY53183.1 - 5.9e-91 303.9 0.0 7.2e-91 303.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-CCCH PF00642.19 EPY53184.1 - 6.3e-12 44.8 16.1 4.2e-07 29.4 1.1 3.4 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EPY53184.1 - 1.4e-07 31.2 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY53184.1 - 2.1e-06 27.2 0.0 3.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53184.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 EPY53184.1 - 0.1 12.5 1.1 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) GTP_EFTU PF00009.22 EPY53185.1 - 2.6e-05 23.7 0.0 0.00024 20.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain HSP9_HSP12 PF04119.7 EPY53186.1 - 4.3e-25 87.5 10.1 5.3e-25 87.2 7.0 1.1 1 0 0 1 1 1 1 Heat shock protein 9/12 LMP PF04778.7 EPY53186.1 - 0.021 14.5 3.6 0.026 14.2 2.5 1.1 1 0 0 1 1 1 0 LMP repeated region DUF4041 PF13250.1 EPY53186.1 - 0.057 12.9 0.3 0.11 12.1 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4041) MT0933_antitox PF14013.1 EPY53186.1 - 0.073 13.1 5.7 3.4 7.8 3.4 2.3 1 1 1 2 2 2 0 MT0933-like antitoxin protein YtxH PF12732.2 EPY53186.1 - 0.16 12.3 3.9 0.31 11.4 2.7 1.5 1 1 1 2 2 2 0 YtxH-like protein Zip PF02535.17 EPY53187.1 - 3.5e-48 164.2 5.6 3.5e-48 164.2 3.9 2.4 2 1 0 2 2 2 1 ZIP Zinc transporter Glutaredoxin PF00462.19 EPY53188.1 - 9.4e-15 54.3 0.0 1.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Cyclin_N PF00134.18 EPY53189.1 - 6.5e-43 145.3 0.8 4.6e-41 139.3 0.5 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPY53189.1 - 3.9e-29 100.9 1.4 4.7e-29 100.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain E1-E2_ATPase PF00122.15 EPY53190.1 - 7.6e-56 188.7 5.6 7.6e-56 188.7 3.9 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPY53190.1 - 2.7e-44 150.8 7.6 2.7e-44 150.8 5.3 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPY53190.1 - 1.5e-23 84.3 0.0 1.5e-22 81.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPY53190.1 - 1.8e-12 47.0 0.0 3.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPY53190.1 - 3e-11 43.8 0.0 1.1e-10 41.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPY53190.1 - 2.2e-07 30.2 0.0 1.3e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPY53190.1 - 9.4e-05 22.0 1.2 0.00013 21.6 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 EPY53190.1 - 2.9 6.5 11.4 0.042 12.5 0.6 2.5 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family V-ATPase_C PF03223.10 EPY53191.1 - 3.3e-107 358.6 9.7 3.7e-107 358.4 6.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Ion_trans PF00520.26 EPY53194.1 - 9e-109 361.3 105.6 1e-36 126.0 8.6 6.1 4 2 1 5 5 5 4 Ion transport protein F-box-like PF12937.2 EPY53195.1 - 0.052 13.2 2.9 0.071 12.8 0.4 2.4 2 1 0 2 2 2 0 F-box-like F-box PF00646.28 EPY53195.1 - 2.3 7.9 6.8 6.4 6.5 0.0 4.2 5 0 0 5 5 5 0 F-box domain NGP1NT PF08153.7 EPY53196.1 - 8.5e-49 164.8 0.2 1.4e-48 164.1 0.2 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EPY53196.1 - 8.6e-19 67.6 0.0 2.4e-15 56.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY53196.1 - 4.3e-06 26.0 0.1 6.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EPY53196.1 - 0.00021 20.5 0.1 0.026 13.7 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EPY53196.1 - 0.00022 21.1 1.9 0.11 12.2 0.0 3.8 3 1 1 4 4 4 1 Dynamin family GTP_EFTU PF00009.22 EPY53196.1 - 0.00039 19.8 0.1 0.17 11.2 0.0 3.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPY53196.1 - 0.0018 17.4 0.0 0.0041 16.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EPY53196.1 - 0.042 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 EPY53196.1 - 0.075 12.4 0.1 8.6 5.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EPY53196.1 - 0.53 10.7 2.3 6.2 7.3 0.0 3.1 4 0 0 4 4 4 0 Miro-like protein MFS_1 PF07690.11 EPY53197.1 - 1.2e-08 34.1 28.7 2e-08 33.3 19.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPY53197.1 - 0.00012 21.6 4.9 0.00012 21.6 3.4 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DAD PF02109.11 EPY53198.1 - 2.2e-41 140.4 3.2 2.7e-41 140.1 2.2 1.0 1 0 0 1 1 1 1 DAD family PalH PF08733.5 EPY53198.1 - 0.00068 18.5 0.3 0.0008 18.3 0.2 1.0 1 0 0 1 1 1 1 PalH/RIM21 DUF2768 PF10966.3 EPY53198.1 - 0.45 10.6 3.6 0.95 9.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Rax2 PF12768.2 EPY53199.1 - 1.9e-29 102.7 0.1 1.9e-29 102.7 0.1 4.1 4 1 0 4 4 4 1 Cortical protein marker for cell polarity Ribosomal_S13_N PF08069.7 EPY53200.1 - 2.5e-28 97.6 0.6 4.3e-28 96.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EPY53200.1 - 7.9e-24 83.2 0.1 1.2e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 RabGAP-TBC PF00566.13 EPY53201.1 - 9.3e-39 133.1 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NuA4 PF09340.5 EPY53202.1 - 2.3e-25 88.0 0.4 2.3e-25 88.0 0.3 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 P34-Arc PF04045.9 EPY53203.1 - 5.1e-99 330.4 1.5 6.8e-99 330.0 1.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Phos_pyr_kin PF08543.7 EPY53204.1 - 1.1e-14 54.2 0.0 1.5e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EPY53204.1 - 8.7e-07 28.3 0.0 5.5e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PX PF00787.19 EPY53205.1 - 5.6e-23 80.8 0.5 1.4e-22 79.5 0.3 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EPY53205.1 - 1.5e-05 24.4 17.8 0.006 15.8 12.3 2.2 1 1 0 1 1 1 1 Vps5 C terminal like Rapamycin_bind PF08771.6 EPY53205.1 - 0.16 12.0 4.2 0.96 9.5 0.3 2.9 2 1 1 3 3 3 0 Rapamycin binding domain Ribosomal_L50 PF10501.4 EPY53205.1 - 0.22 11.4 2.9 0.62 10.0 1.1 2.4 2 1 0 2 2 2 0 Ribosomal subunit 39S Vac_Fusion PF02346.11 EPY53205.1 - 0.71 9.3 3.6 31 4.0 0.0 3.5 4 0 0 4 4 4 0 Chordopoxvirus fusion protein IncA PF04156.9 EPY53205.1 - 0.81 9.2 20.0 2.4 7.7 8.5 2.6 2 1 0 2 2 2 0 IncA protein BLOC1_2 PF10046.4 EPY53205.1 - 0.99 9.5 12.4 10 6.3 1.6 3.6 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 EPY53205.1 - 3.2 6.8 6.2 2.1 7.4 1.2 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF726 PF05277.7 EPY53206.1 - 1.7e-128 428.3 0.4 2.5e-128 427.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EPY53206.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF438 PF04282.8 EPY53206.1 - 0.11 12.3 3.7 0.1 12.3 0.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF438) G-patch PF01585.18 EPY53207.1 - 2.1e-09 37.0 2.0 5.4e-09 35.6 1.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPY53207.1 - 0.00044 20.0 2.5 0.00056 19.6 0.5 2.3 1 1 1 2 2 2 1 DExH-box splicing factor binding site Clr5 PF14420.1 EPY53207.1 - 0.029 14.2 0.6 6.3 6.7 0.0 2.7 2 1 0 2 2 2 0 Clr5 domain DUF2570 PF10828.3 EPY53207.1 - 0.047 13.3 2.4 0.09 12.3 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Dala_Dala_lig_N PF01820.16 EPY53207.1 - 0.11 12.8 0.2 0.11 12.8 0.1 2.4 1 1 2 3 3 3 0 D-ala D-ala ligase N-terminus p25-alpha PF05517.7 EPY53207.1 - 0.26 11.5 0.2 0.26 11.5 0.1 2.2 2 1 1 3 3 3 0 p25-alpha ATP-synt_E PF05680.7 EPY53207.1 - 4.7 7.2 14.0 0.13 12.2 3.4 2.8 2 2 0 2 2 2 0 ATP synthase E chain Ras PF00071.17 EPY53208.1 - 6.1e-60 201.2 0.1 7.1e-60 201.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY53208.1 - 7.6e-20 71.5 0.1 2.6e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPY53208.1 - 1.4e-13 50.5 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPY53208.1 - 5.8e-07 29.1 0.0 1.3e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPY53208.1 - 4.2e-06 26.0 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPY53208.1 - 3.7e-05 23.6 0.0 7.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPY53208.1 - 0.004 16.6 0.1 0.024 14.1 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EPY53208.1 - 0.024 13.8 0.5 0.071 12.2 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPY53208.1 - 0.035 14.0 0.1 0.066 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TPP1 PF10341.4 EPY53209.1 - 1.8e-11 43.9 0.0 4.6e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Rif1_N PF12231.3 EPY53210.1 - 3.4e-93 312.5 1.0 5.4e-93 311.9 0.7 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.20 EPY53211.1 - 8.6e-56 188.9 0.0 1.2e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53211.1 - 1.2e-22 80.2 0.0 1.9e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY53211.1 - 1.9e-07 30.3 0.0 3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPY53211.1 - 0.0037 16.3 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 EPY53211.1 - 0.013 15.8 0.0 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 PAS domain WaaY PF06176.6 EPY53211.1 - 0.05 12.8 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) ETF PF01012.16 EPY53212.1 - 5e-33 114.1 0.4 6.3e-33 113.8 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TRM13 PF05206.9 EPY53213.1 - 3e-69 233.1 0.7 4e-69 232.7 0.5 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 EPY53213.1 - 1.2e-09 37.6 2.1 3.4e-09 36.2 1.5 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 EPY53213.1 - 0.00035 20.2 1.9 0.0012 18.5 1.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain Nucleoporin_C PF03177.9 EPY53214.1 - 6.2e-74 249.5 13.3 8.5e-74 249.1 9.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPY53214.1 - 1.2e-27 96.7 1.3 5.6e-27 94.5 0.5 2.0 2 0 0 2 2 2 1 Nup133 N terminal like Pkinase PF00069.20 EPY53215.1 - 2.9e-34 118.4 0.0 4.3e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53215.1 - 5.2e-12 45.3 0.0 8.4e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ALAD PF00490.16 EPY53216.1 - 1e-117 392.6 0.0 1.1e-117 392.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DASH_Dad2 PF08654.5 EPY53217.1 - 2.4e-18 65.9 0.4 2.7e-18 65.8 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 EPY53217.1 - 0.028 13.9 0.1 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 Tctex-1 PF03645.8 EPY53218.1 - 1.8e-22 79.1 0.2 2e-22 78.9 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Alba PF01918.16 EPY53219.1 - 0.0038 16.7 0.1 0.0054 16.2 0.1 1.2 1 0 0 1 1 1 1 Alba Formyl_trans_N PF00551.14 EPY53220.1 - 2.5e-19 69.4 0.0 4.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EPY53220.1 - 1.2e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Ribosomal_S26e PF01283.14 EPY53222.1 - 8.9e-53 177.3 8.0 1e-52 177.2 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e ubiquitin PF00240.18 EPY53223.1 - 1.3e-34 117.4 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EPY53223.1 - 1.2e-29 101.6 11.4 1.8e-29 101.0 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EPY53223.1 - 4.8e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPY53223.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPY53223.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPY53223.1 - 0.0047 16.7 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPY53223.1 - 0.0089 16.1 0.1 0.01 16.0 0.1 1.2 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPY53223.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EPY53223.1 - 0.17 10.1 0.5 4.3 5.5 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Fer2_3 PF13085.1 EPY53223.1 - 0.28 11.0 2.0 1.3 8.8 1.4 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 EPY53223.1 - 0.71 9.2 4.7 1.1 8.6 3.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_L14e PF01929.12 EPY53224.1 - 1.1e-28 99.3 1.0 1.6e-28 98.8 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EPY53224.1 - 0.00059 19.4 4.4 0.0011 18.5 3.0 1.5 1 0 0 1 1 1 1 KOW motif Nitr_red_assoc PF09655.5 EPY53224.1 - 0.037 14.3 0.9 0.052 13.8 0.7 1.3 1 1 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) COG5 PF10392.4 EPY53225.1 - 0.032 14.1 0.8 0.032 14.1 0.6 2.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 VirC1 PF07015.6 EPY53225.1 - 0.078 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein HECT PF00632.20 EPY53226.1 - 1.3e-90 303.7 0.0 2.6e-90 302.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPY53226.1 - 3.7e-07 29.8 4.8 6.9e-06 25.8 0.5 2.7 2 0 0 2 2 2 2 WW domain PNP_UDP_1 PF01048.15 EPY53227.1 - 2.6e-47 160.7 0.2 3.1e-47 160.5 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily CRM1_C PF08767.6 EPY53228.1 - 1.8e-127 424.6 3.7 1.8e-127 424.6 2.5 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EPY53228.1 - 1.3e-41 141.9 6.2 1.3e-41 141.9 4.3 4.5 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EPY53228.1 - 8.2e-13 48.0 0.2 5.7e-12 45.3 0.1 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Mito_carr PF00153.22 EPY53229.1 - 2.6e-16 59.1 0.2 0.00057 19.5 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein ELO PF01151.13 EPY53230.1 - 3.2e-62 210.0 24.2 4e-62 209.7 16.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Lysis_S PF04971.7 EPY53230.1 - 0.31 10.7 4.1 0.25 11.0 0.1 2.8 1 1 2 3 3 3 0 Lysis protein S COX5A PF02284.11 EPY53232.1 - 1.4e-34 118.2 0.0 1.7e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va MCM PF00493.18 EPY53233.1 - 1e-141 471.5 0.5 1.3e-141 471.1 0.4 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPY53233.1 - 4.5e-22 78.8 0.5 1.4e-21 77.1 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPY53233.1 - 7.4e-06 25.2 0.0 0.00087 18.5 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPY53233.1 - 1.8e-05 24.4 0.0 4.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPY53233.1 - 0.0013 18.3 0.1 0.0075 15.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPY53233.1 - 0.02 14.3 0.0 0.92 8.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.9 EPY53233.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TrkH PF02386.11 EPY53234.1 - 1.8e-122 408.3 19.4 1.6e-119 398.6 9.6 2.1 2 0 0 2 2 2 2 Cation transport protein tRNA-synt_2b PF00587.20 EPY53235.1 - 1.5e-64 216.7 0.1 2.6e-64 215.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPY53235.1 - 1.9e-22 78.9 0.2 9.8e-22 76.7 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain GSH_synth_ATP PF03917.12 EPY53236.1 - 3.1e-136 453.8 0.1 3.5e-136 453.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EPY53236.1 - 2.5e-33 114.3 0.0 4.7e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase MUG113 PF13455.1 EPY53237.1 - 1.8e-11 44.3 0.5 3.7e-11 43.3 0.4 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EPY53237.1 - 4.5e-11 43.0 0.1 9.8e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain DUF866 PF05907.8 EPY53237.1 - 0.038 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) MFS_1 PF07690.11 EPY53239.1 - 0.0014 17.4 6.9 0.005 15.6 4.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0233 PF06781.7 EPY53239.1 - 0.035 13.7 0.5 0.062 12.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) FA_desaturase PF00487.19 EPY53240.1 - 0.0095 15.3 1.8 0.014 14.8 1.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase TctA PF01970.11 EPY53240.1 - 0.12 10.7 5.8 0.17 10.2 4.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family MRAP PF15183.1 EPY53240.1 - 2.6 7.7 5.1 6 6.5 3.5 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF2101 PF09874.4 EPY53240.1 - 4.1 6.8 8.0 7.6 5.9 5.3 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) MUG2_C PF08593.5 EPY53242.1 - 8.9e-16 57.8 0.5 5.1e-15 55.4 0.0 2.5 3 0 0 3 3 3 1 Meiotically up-regulated glycoproteins C-terminal DUF3037 PF11236.3 EPY53242.1 - 0.14 12.2 0.8 0.31 11.1 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Peptidase_S46 PF10459.4 EPY53242.1 - 0.22 9.9 4.5 0.27 9.5 3.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Matrilin_ccoil PF10393.4 EPY53242.1 - 8.1 5.9 6.3 31 4.0 0.0 3.4 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Lung_7-TM_R PF06814.8 EPY53243.1 - 0.074 12.0 14.3 0.2 10.5 9.9 1.7 1 1 0 1 1 1 0 Lung seven transmembrane receptor Pox_TAA1 PF03295.9 EPY53244.1 - 0.14 11.8 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal Init_tRNA_PT PF04179.7 EPY53246.1 - 6.5e-102 341.7 0.0 7.9e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Erf4 PF10256.4 EPY53247.1 - 1.2e-25 89.6 0.1 1.9e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNR_inhib PF08591.5 EPY53249.1 - 9.2e-07 29.7 0.0 1.3e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF4602 PF15375.1 EPY53250.1 - 0.75 9.8 33.3 0.078 13.0 16.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4602) His_biosynth PF00977.16 EPY53251.1 - 3.8e-35 121.2 0.0 4.7e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 EPY53251.1 - 0.039 13.1 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase STE3 PF02076.10 EPY53252.1 - 1.1e-61 208.4 20.1 1.4e-61 208.0 13.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_1 PF00001.16 EPY53252.1 - 0.0041 16.3 5.8 0.0041 16.3 4.0 2.4 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF247 PF03140.10 EPY53252.1 - 0.082 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function DUF3958 PF13125.1 EPY53252.1 - 0.12 12.2 0.9 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) MAPEG PF01124.13 EPY53252.1 - 0.56 9.8 0.0 0.56 9.8 0.0 3.0 3 1 1 4 4 4 0 MAPEG family ABC_membrane PF00664.18 EPY53253.1 - 4.9e-92 308.2 37.2 9.2e-48 163.0 6.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPY53253.1 - 1.3e-47 161.5 0.0 1.8e-29 102.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPY53253.1 - 3.7e-10 39.4 3.6 0.0051 16.0 0.2 4.3 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPY53253.1 - 7.2e-07 29.4 0.0 2.3 8.0 0.0 4.7 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 EPY53253.1 - 2.8e-06 26.7 0.1 0.082 12.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPY53253.1 - 6e-06 26.3 0.8 0.046 13.7 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EPY53253.1 - 4.8e-05 23.7 0.0 0.09 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPY53253.1 - 8.5e-05 21.7 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPY53253.1 - 8.6e-05 22.4 2.0 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EPY53253.1 - 0.0001 21.7 0.0 0.32 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EPY53253.1 - 0.0012 19.3 0.0 2.3 8.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 EPY53253.1 - 0.0051 16.6 0.6 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF87 NB-ARC PF00931.17 EPY53253.1 - 0.0087 14.9 0.1 3.7 6.3 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.1 EPY53253.1 - 0.015 15.4 1.0 6 7.0 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPY53253.1 - 0.016 14.6 0.7 1.2 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EPY53253.1 - 0.022 13.6 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.4 EPY53253.1 - 0.023 13.3 2.6 0.39 9.2 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_17 PF13207.1 EPY53253.1 - 0.05 14.4 0.0 0.42 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EPY53253.1 - 0.054 13.3 0.3 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 EPY53253.1 - 0.17 10.6 0.1 4.6 5.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 EPY53253.1 - 0.23 10.9 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EPY53253.1 - 0.39 10.2 0.2 8.9 5.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain UBA PF00627.26 EPY53254.1 - 4e-07 29.6 0.0 8.2e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Spo12 PF05032.7 EPY53255.1 - 1.6e-15 56.4 1.4 2.6e-15 55.7 1.0 1.4 1 0 0 1 1 1 1 Spo12 family MMR_HSR1 PF01926.18 EPY53256.1 - 7.5e-17 61.3 0.1 8.8e-15 54.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY53256.1 - 1.1e-07 31.2 0.2 2.8e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EPY53256.1 - 8.8e-05 21.7 0.1 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPY53256.1 - 0.00017 21.4 2.5 0.074 12.8 0.7 3.2 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 EPY53256.1 - 0.0043 16.1 0.1 0.0095 15.0 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EPY53256.1 - 0.029 14.8 0.0 0.08 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein LTV PF04180.9 EPY53257.1 - 8.2e-112 374.7 30.3 2.1e-111 373.4 21.0 1.6 1 1 0 1 1 1 1 Low temperature viability protein zf-CSL PF05207.8 EPY53258.1 - 1.4e-23 82.0 1.0 1.9e-23 81.6 0.7 1.2 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 EPY53258.1 - 0.034 13.7 0.3 0.048 13.2 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF164 PF02591.10 EPY53258.1 - 0.035 13.9 0.1 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain zinc_ribbon_4 PF13717.1 EPY53258.1 - 0.061 13.0 0.3 0.096 12.4 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EPY53258.1 - 0.094 12.6 1.7 0.21 11.5 1.2 1.6 1 1 0 1 1 1 0 Zinc ribbon domain MutS_V PF00488.16 EPY53259.1 - 1.6e-77 260.0 0.0 2.4e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPY53259.1 - 3.6e-41 141.2 0.3 6.8e-41 140.3 0.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPY53259.1 - 2.1e-26 92.1 0.0 5.1e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EPY53259.1 - 4.5e-15 55.9 3.0 5e-15 55.7 0.2 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EPY53259.1 - 8.7e-10 38.6 0.1 2.9e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV Longin PF13774.1 EPY53259.1 - 0.015 14.8 0.4 0.11 12.1 0.2 2.6 1 1 0 1 1 1 0 Regulated-SNARE-like domain Ribosomal_L1 PF00687.16 EPY53260.1 - 2.4e-54 183.9 1.2 2.4e-54 183.9 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Brr6_like_C_C PF10104.4 EPY53262.1 - 4.6e-29 100.6 2.8 6.3e-29 100.2 2.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain COesterase PF00135.23 EPY53264.1 - 1.9e-09 36.7 0.2 2.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EPY53264.1 - 0.0021 17.6 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPY53264.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPY53264.1 - 0.03 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPY53264.1 - 0.033 13.0 0.1 0.052 12.3 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase Methyltransf_16 PF10294.4 EPY53265.1 - 1.5e-15 57.0 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 EPY53265.1 - 0.0049 15.8 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family GidB PF02527.10 EPY53265.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.2 EPY53265.1 - 0.022 15.3 0.0 0.038 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EPY53265.1 - 0.032 13.3 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PS_pyruv_trans PF04230.8 EPY53266.1 - 1.5e-29 103.6 0.0 2.3e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase ox_reductase_C PF08635.5 EPY53267.1 - 2e-72 241.2 0.1 2.9e-72 240.7 0.1 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EPY53267.1 - 1.7e-18 67.2 0.0 2.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPY53267.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_transf_20 PF00982.16 EPY53268.1 - 1.1e-156 522.0 0.0 1.4e-156 521.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPY53268.1 - 2.8e-53 180.2 0.0 4.5e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase RNA_lig_T4_1 PF09511.5 EPY53268.1 - 0.033 13.6 0.2 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 RNA ligase CPDase PF07823.6 EPY53269.1 - 4.7e-30 104.5 0.2 6.9e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EPY53269.1 - 0.0019 17.9 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Orbi_VP4 PF05059.7 EPY53269.1 - 0.077 10.7 0.0 0.092 10.4 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein BRCT PF00533.21 EPY53270.1 - 3.1e-07 30.4 0.0 0.0001 22.3 0.0 3.0 2 1 1 3 3 3 2 BRCA1 C Terminus (BRCT) domain DUF604 PF04646.7 EPY53270.1 - 0.042 13.0 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF604 YchF-GTPase_C PF06071.8 EPY53271.1 - 2.2e-28 97.8 0.2 3.5e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPY53271.1 - 9e-15 54.6 0.0 1.7e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY53271.1 - 9.5e-05 21.7 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EPY53271.1 - 0.0024 16.7 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 ArgK protein TGS PF02824.16 EPY53271.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 TGS domain Peptidase_M16 PF00675.15 EPY53272.1 - 2.3e-38 131.2 0.1 2.5e-37 127.9 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPY53272.1 - 2.6e-30 105.4 0.1 3.2e-19 69.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Flavodoxin_5 PF12724.2 EPY53272.1 - 0.0098 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain MPP6 PF10175.4 EPY53273.1 - 2.5e-05 24.5 2.0 6.4e-05 23.2 0.0 2.6 1 1 1 2 2 2 1 M-phase phosphoprotein 6 LZ_Tnp_IS66 PF13007.2 EPY53273.1 - 8.9 7.0 9.9 1.1 10.0 0.5 2.6 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain 2-Hacid_dh_C PF02826.14 EPY53274.1 - 4.8e-57 191.9 0.0 9.4e-57 191.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPY53274.1 - 3e-17 62.3 0.0 3.4e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPY53274.1 - 0.0002 21.2 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPY53274.1 - 0.019 15.3 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EPY53274.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EPY53274.1 - 0.067 13.0 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_23 PF13489.1 EPY53275.1 - 2.7e-11 43.4 0.0 4.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY53275.1 - 4.5e-06 26.3 0.0 1.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 EPY53275.1 - 1e-05 25.8 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_18 PF12847.2 EPY53275.1 - 1.6e-05 25.4 0.0 3.2e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY53275.1 - 4.1e-05 23.9 0.1 0.0003 21.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EPY53275.1 - 4.1e-05 23.1 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.1 EPY53275.1 - 0.0001 22.6 0.0 0.00021 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY53275.1 - 0.00016 21.6 0.0 0.00055 19.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY53275.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EPY53275.1 - 0.0017 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 EPY53275.1 - 0.0048 16.2 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 EPY53275.1 - 0.0083 16.6 0.0 0.029 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPY53275.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EPY53275.1 - 0.1 11.3 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 EPY53275.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EPY53275.1 - 0.12 11.3 0.0 0.97 8.4 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase DPPIV_N PF00930.16 EPY53276.1 - 3.3e-97 325.2 5.7 4.7e-97 324.7 4.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EPY53276.1 - 2e-49 167.6 4.0 3.3e-49 166.9 2.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPY53276.1 - 4.2e-07 29.8 0.0 7.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY53276.1 - 0.00037 20.4 0.1 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPY53276.1 - 0.0031 16.9 0.4 1.5 8.2 0.3 2.3 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2920 PF11144.3 EPY53276.1 - 0.0077 15.2 0.0 0.022 13.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S15 PF02129.13 EPY53276.1 - 0.0081 15.6 4.3 0.021 14.2 0.4 2.9 2 2 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EPY53276.1 - 0.01 15.1 0.0 0.052 12.8 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 EPY53276.1 - 0.012 14.1 0.0 0.02 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase PF00702.21 EPY53277.1 - 1.6e-23 84.2 0.0 5.2e-23 82.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPY53277.1 - 7.2e-23 81.7 0.0 2e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPY53277.1 - 4.1e-19 68.5 0.0 8.9e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EPY53277.1 - 1.1e-05 25.2 0.0 3.6e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPY53277.1 - 0.006 16.1 0.5 0.04 13.4 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EPY53277.1 - 0.012 14.8 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Runt PF00853.14 EPY53277.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Runt domain SHS2_Rpb7-N PF03876.12 EPY53278.1 - 5.4e-17 61.6 0.0 8.4e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPY53278.1 - 5.1e-11 42.5 0.0 8.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EPY53278.1 - 0.065 13.4 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 C2 PF00168.25 EPY53279.1 - 2.3e-52 174.7 2.1 1.6e-18 66.2 0.0 4.5 4 0 0 4 4 4 4 C2 domain DOCK-C2 PF14429.1 EPY53279.1 - 1.4e-05 24.7 0.1 0.013 15.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins CEP76-C2 PF15627.1 EPY53279.1 - 0.03 13.8 0.0 3.5 7.1 0.0 2.6 2 0 0 2 2 2 0 CEP76 C2 domain Ribosomal_L34e PF01199.13 EPY53279.1 - 0.039 14.1 0.1 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L34e DUF2404 PF10296.4 EPY53279.1 - 0.048 13.7 0.0 0.2 11.7 0.0 2.1 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) GTP_EFTU PF00009.22 EPY53280.1 - 9.8e-62 207.7 0.1 1.4e-61 207.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPY53280.1 - 1.5e-33 114.9 0.0 3.9e-33 113.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPY53280.1 - 6.5e-20 70.7 0.0 1.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EPY53280.1 - 1.5e-13 50.3 0.0 3.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EPY53280.1 - 3.4e-12 46.3 0.7 1.5e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPY53280.1 - 6.4e-05 22.8 0.1 0.00013 21.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAP_assoc PF03828.14 EPY53280.1 - 0.16 11.9 0.2 0.48 10.4 0.1 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase DUF1749 PF08538.5 EPY53281.1 - 2.3e-102 341.9 0.0 2.8e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 EPY53281.1 - 2.8e-05 23.9 0.0 4.7e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EPY53281.1 - 0.0037 16.2 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.16 EPY53281.1 - 0.0048 16.1 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPY53281.1 - 0.006 16.4 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY53281.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 EPY53281.1 - 0.033 13.2 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Arginase PF00491.16 EPY53282.1 - 2.9e-86 289.2 0.0 3.6e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPY53282.1 - 0.0043 17.2 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 UPF0489 domain HhH-GPD PF00730.20 EPY53283.1 - 8.6e-17 61.3 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.1 EPY53283.1 - 0.0003 20.8 0.8 0.02 15.0 0.3 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix domain AA_permease_2 PF13520.1 EPY53284.1 - 1.4e-53 182.0 54.2 1.6e-53 181.7 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPY53284.1 - 6.8e-24 84.0 48.7 9.3e-24 83.6 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 EPY53285.1 - 4.3e-32 111.0 3.7 4.3e-32 111.0 2.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY53285.1 - 1.7e-09 37.4 11.5 1.7e-09 37.4 8.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPY53285.1 - 0.57 10.3 8.4 1.3 9.2 5.8 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF2797 PF10977.3 EPY53285.1 - 1.7 8.1 4.3 2.9 7.4 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) AcetylCoA_hyd_C PF13336.1 EPY53286.1 - 7.1e-42 142.6 0.0 1.1e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EPY53286.1 - 1.2e-23 83.9 0.0 3.7e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.7 EPY53286.1 - 3.4e-05 22.6 0.4 0.00014 20.6 0.2 1.9 2 1 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) Aminotran_1_2 PF00155.16 EPY53287.1 - 1.9e-68 231.0 0.1 2.5e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPY53287.1 - 6.7e-08 31.2 0.0 9.7e-08 30.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EPY53287.1 - 2.9e-05 23.3 0.0 4.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPY53287.1 - 0.00014 20.7 0.0 0.00021 20.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cu_amine_oxid PF01179.15 EPY53288.1 - 6.1e-172 571.9 0.1 7.4e-172 571.7 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPY53288.1 - 1.3e-25 89.4 0.1 2.9e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPY53288.1 - 3.7e-10 39.7 0.0 7.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Ammonium_transp PF00909.16 EPY53289.1 - 3.3e-95 318.9 23.6 1.3e-53 181.9 7.3 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family ADH_zinc_N PF00107.21 EPY53290.1 - 5.8e-14 51.7 0.0 1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EPY53290.1 - 0.00082 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 EPY53290.1 - 0.00091 20.1 0.0 0.0017 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPY53290.1 - 0.0095 15.6 0.2 0.04 13.6 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EPY53291.1 - 8.9e-22 77.6 0.3 6.8e-21 74.7 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY53291.1 - 2.2e-17 62.6 0.1 5.1e-17 61.4 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPY53291.1 - 3e-13 49.2 0.1 1.8e-12 46.7 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPY53291.1 - 2.1e-10 40.8 0.0 4.6e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPY53291.1 - 3e-06 26.3 0.2 7.2e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPY53291.1 - 5.6e-06 26.3 0.2 3.9e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EPY53291.1 - 0.0017 17.6 0.1 0.0034 16.6 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EPY53291.1 - 0.017 14.7 0.7 0.15 11.6 0.2 2.5 2 1 0 2 2 2 0 KR domain Ldh_1_N PF00056.18 EPY53291.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EPY53291.1 - 0.049 13.4 0.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EPY53292.1 - 8.4e-22 77.9 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EPY53292.1 - 6.2e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EPY53292.1 - 0.0053 15.7 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase ATP-synt_E PF05680.7 EPY53292.1 - 0.031 14.2 0.1 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase E chain Glyco_hydro_38 PF01074.17 EPY53293.1 - 1.6e-90 303.0 0.2 3e-90 302.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EPY53293.1 - 7.6e-71 239.2 0.0 1.3e-70 238.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EPY53293.1 - 1.2e-23 83.0 0.0 2.6e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain adh_short PF00106.20 EPY53294.1 - 1.2e-08 35.0 0.0 1.5e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Glu_synthase PF01645.12 EPY53294.1 - 0.11 11.4 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase M-factor PF03855.8 EPY53295.1 - 8.4e-06 25.6 6.2 1.1e-05 25.3 4.3 1.2 1 0 0 1 1 1 1 M-factor His_Phos_1 PF00300.17 EPY53296.1 - 3.6e-24 85.6 0.0 4.3e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1877 PF08974.5 EPY53296.1 - 0.0053 16.4 0.1 0.0086 15.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) ADH_zinc_N PF00107.21 EPY53297.1 - 2.8e-24 85.1 0.0 5e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPY53297.1 - 1.2e-05 26.2 0.0 2.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ABC2_membrane PF01061.19 EPY53298.1 - 3.5e-69 232.1 62.6 6.5e-39 133.2 11.5 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPY53298.1 - 1e-25 90.6 0.0 1.2e-14 54.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EPY53298.1 - 1.2e-21 76.3 9.0 2.1e-13 49.7 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter AAA_25 PF13481.1 EPY53298.1 - 0.2 11.0 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 EPY53298.1 - 1.4 7.8 57.1 0.0064 15.5 17.9 3.5 2 1 1 3 3 3 0 ABC-2 family transporter protein Glyco_hydro_31 PF01055.21 EPY53299.1 - 1.4e-159 531.7 4.8 1.9e-159 531.2 3.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DJ-1_PfpI PF01965.19 EPY53301.1 - 2.4e-28 98.4 0.2 3.6e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPY53301.1 - 0.00018 20.9 0.0 0.00036 19.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Paf67 PF10255.4 EPY53301.1 - 0.0088 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 FMN_dh PF01070.13 EPY53302.1 - 4.5e-115 384.3 0.0 5.5e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EPY53302.1 - 2.8e-05 23.2 0.7 4.1e-05 22.6 0.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EPY53302.1 - 0.00026 20.0 0.1 0.00037 19.5 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EPY53302.1 - 0.00097 18.3 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EPY53302.1 - 0.0027 16.8 0.3 0.64 9.0 0.2 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Fungal_trans PF04082.13 EPY53303.1 - 1.1e-27 96.5 3.0 2.3e-27 95.5 2.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY53303.1 - 4e-09 36.2 10.3 6.7e-09 35.5 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EPY53304.1 - 1.2e-35 120.9 0.0 1.6e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53304.1 - 4.7e-21 74.5 0.0 2.7e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53304.1 - 3.3e-15 55.6 0.1 2.9e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EPY53304.1 - 0.023 14.2 0.4 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Rot1 PF10681.4 EPY53305.1 - 5.6e-79 264.4 0.2 8.1e-79 263.8 0.1 1.2 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Ribosomal_S17 PF00366.15 EPY53306.1 - 6e-31 106.2 1.0 9.3e-31 105.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Iso_dh PF00180.15 EPY53307.1 - 1.7e-95 319.9 0.0 2.6e-95 319.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribul_P_3_epim PF00834.14 EPY53308.1 - 8.6e-75 250.2 0.0 1e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EPY53308.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 EPY53308.1 - 0.038 13.5 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Fig1 PF12351.3 EPY53310.1 - 5.3e-20 72.0 12.9 5.3e-20 72.0 9.0 1.7 1 1 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EPY53310.1 - 2.3e-05 24.0 26.9 0.00018 21.1 18.7 2.0 1 1 0 1 1 1 1 SUR7/PalI family DUF4383 PF14325.1 EPY53310.1 - 3.8 7.5 13.4 3.8 7.5 5.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4383) Pkinase PF00069.20 EPY53311.1 - 4.8e-74 248.7 0.0 5.7e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53311.1 - 2e-30 105.7 0.0 3.4e-30 104.9 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EPY53311.1 - 2.7e-05 23.3 0.2 6.4e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY53311.1 - 3.2e-05 23.0 0.0 0.00017 20.6 0.0 2.0 1 1 2 3 3 3 1 Kinase-like APH PF01636.18 EPY53311.1 - 0.0026 17.5 0.8 0.024 14.3 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EPY53311.1 - 0.0058 16.0 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family HEM4 PF02602.10 EPY53312.1 - 7.8e-35 120.1 0.0 8.9e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD ATP-synt_F PF01990.12 EPY53312.1 - 0.074 13.4 0.1 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Myb_DNA-bind_6 PF13921.1 EPY53313.1 - 0.076 13.1 4.0 0.097 12.7 0.1 3.0 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPY53313.1 - 0.13 12.3 9.1 0.14 12.2 0.0 4.0 4 1 0 4 4 4 0 Myb-like DNA-binding domain Gti1_Pac2 PF09729.4 EPY53314.1 - 5e-52 176.1 0.0 6e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family Maf1 PF09174.5 EPY53315.1 - 1.2e-53 181.6 0.6 1.4e-53 181.3 0.4 1.1 1 0 0 1 1 1 1 Maf1 regulator DUF1754 PF08555.5 EPY53316.1 - 6.2e-12 45.9 10.7 6.2e-12 45.9 7.4 1.6 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Sigma70_ner PF04546.8 EPY53316.1 - 0.0033 17.0 8.0 0.0039 16.8 5.6 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Paramyxo_ncap PF00973.14 EPY53316.1 - 0.12 11.0 6.0 0.14 10.8 4.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2362 PF10154.4 EPY53316.1 - 0.5 8.9 5.9 0.61 8.6 4.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) CDC27 PF09507.5 EPY53316.1 - 0.79 8.8 15.4 0.94 8.6 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM60A PF15396.1 EPY53316.1 - 1.4 8.6 8.2 1.6 8.4 5.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A JAB PF01398.16 EPY53317.1 - 1.7e-35 121.1 0.0 2.9e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPY53317.1 - 2.3e-24 85.6 1.3 4.1e-24 84.8 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EPY53317.1 - 3.9e-08 32.7 0.0 6.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GCV_T PF01571.16 EPY53318.1 - 2.2e-65 219.9 0.0 2.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPY53318.1 - 1.2e-23 82.9 0.1 2.1e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EPY53318.1 - 0.00048 20.0 0.0 0.0031 17.3 0.0 2.0 1 1 0 2 2 2 1 Sarcosine oxidase, gamma subunit family PS_Dcarbxylase PF02666.10 EPY53319.1 - 7.6e-55 185.3 0.0 1.4e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EPY53319.1 - 3e-14 52.6 0.1 9.2e-14 51.0 0.1 1.9 1 0 0 1 1 1 1 C2 domain Glycos_transf_2 PF00535.21 EPY53320.1 - 1.6e-33 115.7 0.0 2e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPY53320.1 - 1.9e-09 37.7 0.0 3e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EPY53320.1 - 1.1e-07 31.2 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EPY53320.1 - 8.6e-05 21.8 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EPY53320.1 - 0.15 12.4 0.0 0.45 10.8 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 2 S10_plectin PF03501.10 EPY53321.1 - 2.6e-42 142.6 0.0 3.1e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 EPY53322.1 - 7.6e-40 136.2 2.3 7.6e-40 136.2 1.6 1.5 2 0 0 2 2 2 1 Telomere stability and silencing AAA PF00004.24 EPY53323.1 - 1.1e-48 164.7 0.0 3.7e-41 140.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPY53323.1 - 1.5e-07 31.5 0.0 1.4e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPY53323.1 - 4.5e-07 30.0 0.0 4.1e-06 26.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EPY53323.1 - 3.2e-06 26.6 0.0 8.4e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EPY53323.1 - 2.5e-05 24.4 0.0 0.0033 17.5 0.0 3.6 2 2 1 3 3 2 1 AAA domain AAA_5 PF07728.9 EPY53323.1 - 6.7e-05 22.6 0.1 0.00099 18.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPY53323.1 - 0.00061 19.4 0.0 0.002 17.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EPY53323.1 - 0.00086 19.4 0.0 0.0042 17.2 0.0 2.3 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 EPY53323.1 - 0.0017 18.4 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 EPY53323.1 - 0.0018 18.1 0.1 0.0073 16.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EPY53323.1 - 0.0033 16.8 1.0 0.013 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPY53323.1 - 0.0045 17.8 0.0 0.0045 17.8 0.0 3.3 4 2 0 4 4 2 1 AAA domain AAA_14 PF13173.1 EPY53323.1 - 0.0054 16.6 0.0 0.021 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPY53323.1 - 0.0089 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EPY53323.1 - 0.012 15.1 0.0 0.4 10.1 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Bromodomain PF00439.20 EPY53323.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Bromodomain AAA_28 PF13521.1 EPY53323.1 - 0.017 15.0 0.4 0.071 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPY53323.1 - 0.019 15.2 0.0 0.019 15.2 0.0 3.9 4 0 0 4 4 3 0 AAA domain RuvB_N PF05496.7 EPY53323.1 - 0.024 13.7 0.0 0.092 11.7 0.0 2.0 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EPY53323.1 - 0.024 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EPY53323.1 - 0.025 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.8 EPY53323.1 - 0.027 13.2 0.1 0.074 11.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 EPY53323.1 - 0.029 14.0 0.0 0.1 12.2 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 EPY53323.1 - 0.069 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EPY53323.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.0 4 1 0 4 4 1 0 ABC transporter ResIII PF04851.10 EPY53323.1 - 0.38 10.5 4.1 2.2 8.0 0.0 3.2 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EPY53323.1 - 1.1 8.8 0.0 1.1 8.8 0.0 3.8 4 1 0 4 4 4 0 AAA domain DUF3336 PF11815.3 EPY53324.1 - 3.7e-41 140.0 1.0 5.7e-41 139.4 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPY53324.1 - 6.2e-18 65.4 0.1 1.3e-17 64.4 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PLA2_B PF01735.13 EPY53325.1 - 5.4e-181 602.0 5.1 6.4e-181 601.8 3.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ndc1_Nup PF09531.5 EPY53326.1 - 1.9e-96 323.8 22.3 2.1e-96 323.6 15.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Cyto_heme_lyase PF01265.12 EPY53327.1 - 3.6e-76 256.1 1.5 6.6e-76 255.3 1.0 1.4 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase BsuPI PF12690.2 EPY53327.1 - 0.011 15.3 0.8 0.098 12.3 0.0 2.2 2 0 0 2 2 2 0 Intracellular proteinase inhibitor GHMP_kinases_N PF00288.21 EPY53329.1 - 2.6e-11 43.4 0.3 9.4e-11 41.6 0.2 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPY53329.1 - 0.059 13.5 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal COX7C PF02935.11 EPY53330.1 - 8.9e-14 51.0 0.3 9.6e-14 50.9 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc FlxA PF14282.1 EPY53331.1 - 0.03 14.2 4.2 0.039 13.9 2.9 1.2 1 0 0 1 1 1 0 FlxA-like protein Med9 PF07544.8 EPY53331.1 - 0.31 10.7 3.4 1.3 8.8 2.3 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CBS PF00571.23 EPY53332.1 - 7.3e-41 137.7 10.9 9.8e-11 41.2 0.1 5.5 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EPY53332.1 - 7e-12 44.8 0.0 1.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Aconitase PF00330.15 EPY53333.1 - 2.9e-98 329.3 0.4 1.3e-97 327.1 0.2 2.0 2 1 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPY53333.1 - 2.6e-44 150.4 0.0 4.2e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Glucan_synthase PF02364.10 EPY53335.1 - 0 1431.3 0.0 0 1431.3 0.0 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPY53335.1 - 2.9e-37 127.1 0.7 1.1e-36 125.3 0.5 2.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1772 PF08592.6 EPY53335.1 - 1.9 8.2 14.7 6.5 6.4 0.4 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Peptidase_M20 PF01546.23 EPY53336.1 - 1.5e-25 89.7 0.0 2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPY53336.1 - 1.2e-09 37.8 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EPY53336.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 tRNA-synt_2b PF00587.20 EPY53337.1 - 3.3e-46 157.0 0.1 5.3e-46 156.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPY53337.1 - 1.1e-18 66.9 0.6 2.2e-18 65.9 0.4 1.5 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_S2 PF00318.15 EPY53338.1 - 4.6e-53 179.5 0.1 4.1e-52 176.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 MIF4G PF02854.14 EPY53339.1 - 8.9e-32 110.1 4.2 1.8e-31 109.1 2.9 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EPY53339.1 - 3.3e-25 87.9 0.1 1.3e-24 86.0 0.0 2.2 2 0 0 2 2 2 1 MA3 domain SHMT PF00464.14 EPY53340.1 - 5.7e-206 683.5 0.0 6.6e-206 683.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EPY53340.1 - 0.00011 21.5 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPY53340.1 - 0.0087 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V CHCH PF06747.8 EPY53341.1 - 5.3e-07 29.3 2.6 7.2e-07 28.9 1.8 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EPY53341.1 - 0.0058 16.3 1.1 0.007 16.1 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like OTU PF02338.14 EPY53342.1 - 4.5e-12 46.6 0.0 8.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3446 PF11928.3 EPY53342.1 - 0.049 13.8 5.1 0.14 12.3 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Ribosomal_S9 PF00380.14 EPY53342.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Septin PF00735.13 EPY53343.1 - 1.1e-88 296.9 0.1 1.1e-88 296.9 0.0 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EPY53343.1 - 6.4e-05 22.8 0.1 0.00025 21.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EPY53343.1 - 0.00031 20.1 0.1 0.002 17.5 0.0 2.3 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.22 EPY53343.1 - 0.0062 15.9 4.9 0.24 10.8 0.1 3.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EPY53343.1 - 0.013 16.0 2.4 0.023 15.1 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein Mem_trans PF03547.13 EPY53343.1 - 0.017 13.4 1.3 0.019 13.2 0.9 1.2 1 0 0 1 1 1 0 Membrane transport protein UPF0079 PF02367.12 EPY53343.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MCPVI PF02993.9 EPY53343.1 - 0.22 11.6 9.6 0.45 10.6 6.6 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Dynamin_N PF00350.18 EPY53343.1 - 0.42 10.4 0.0 0.42 10.4 0.0 4.3 4 1 0 4 4 3 0 Dynamin family DUF4045 PF13254.1 EPY53343.1 - 3.6 6.7 23.7 0.33 10.1 12.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Exonuc_VII_L PF02601.10 EPY53343.1 - 7.4 5.6 20.1 1.7 7.7 3.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ndc1_Nup PF09531.5 EPY53343.1 - 8 4.7 8.6 14 3.9 6.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1212 PF06738.7 EPY53344.1 - 2.5e-40 138.0 7.9 2.2e-36 125.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPY53344.1 - 1.4e-18 67.0 13.1 1.4e-18 67.0 9.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Clathrin PF00637.15 EPY53345.1 - 0.0068 16.0 0.1 0.0068 16.0 0.1 3.1 5 0 0 5 5 5 1 Region in Clathrin and VPS PC4 PF02229.11 EPY53346.1 - 1.9e-21 75.0 0.2 3.2e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Nop14 PF04147.7 EPY53346.1 - 1.2 6.9 17.7 1.4 6.7 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 EPY53346.1 - 1.4 8.8 15.3 1.7 8.5 10.6 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DBINO PF13892.1 EPY53346.1 - 2.9 7.9 11.0 0.11 12.4 2.2 2.1 1 1 0 2 2 2 0 DNA-binding domain DUF912 PF06024.7 EPY53346.1 - 8.7 6.4 7.0 3.3 7.8 1.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ras PF00071.17 EPY53348.1 - 5e-51 172.3 0.0 5.9e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY53348.1 - 2.1e-13 50.7 0.0 6.6e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPY53348.1 - 4.8e-06 25.9 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY53348.1 - 0.00073 18.7 0.0 0.00084 18.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EPY53348.1 - 0.042 14.1 0.1 0.065 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EPY53348.1 - 0.064 12.4 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.5 EPY53349.1 - 4e-23 80.8 1.1 4.8e-23 80.6 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DUF310 PF03750.8 EPY53349.1 - 0.06 13.5 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF310) zf-Nse PF11789.3 EPY53350.1 - 1.8e-18 65.8 0.9 3.1e-18 65.0 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPY53350.1 - 0.0027 17.3 0.9 0.0065 16.1 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger SbcD_C PF12320.3 EPY53350.1 - 0.014 15.4 0.6 0.014 15.4 0.4 1.7 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain zf-RING_2 PF13639.1 EPY53350.1 - 0.027 14.2 1.8 0.05 13.4 1.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 EPY53350.1 - 0.046 13.2 2.8 0.089 12.3 1.9 1.5 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Rtf2 PF04641.7 EPY53350.1 - 0.092 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Myb_DNA-binding PF00249.26 EPY53351.1 - 0.0009 19.2 0.1 0.0032 17.4 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPY53351.1 - 0.034 14.2 0.5 0.11 12.6 0.1 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain Med13_C PF06333.7 EPY53353.1 - 7.4e-20 70.8 2.4 1.4e-19 69.9 1.6 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal DUF2011 PF09428.5 EPY53354.1 - 0.88 9.4 15.2 1.6 8.5 10.6 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Tom37_C PF11801.3 EPY53355.1 - 8.7e-07 28.9 0.9 0.0024 17.7 0.1 2.3 1 1 1 2 2 2 2 Tom37 C-terminal domain GST_C_3 PF14497.1 EPY53355.1 - 0.004 17.5 0.0 0.0067 16.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_17 PF00332.13 EPY53355.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 DUF2419 PF10343.4 EPY53356.1 - 7.6e-112 373.2 0.0 9e-112 373.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Pho88 PF10032.4 EPY53357.1 - 1.3e-65 220.2 0.0 1.4e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) WD40 PF00400.27 EPY53358.1 - 2.5e-09 36.6 0.7 0.0083 15.9 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPY53358.1 - 0.073 12.5 0.0 17 4.9 0.0 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 EPY53358.1 - 0.079 12.0 0.2 2.3 7.2 0.0 3.0 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DASH_Dam1 PF08653.5 EPY53359.1 - 4.4e-24 83.9 1.2 6.1e-24 83.5 0.2 1.7 2 0 0 2 2 2 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 EPY53360.1 - 8.2e-42 142.3 0.1 1.7e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EPY53360.1 - 2.2e-06 27.6 0.1 4.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ubiquitin PF00240.18 EPY53361.1 - 5.2e-34 115.4 1.8 6.1e-34 115.2 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EPY53361.1 - 8.5e-25 86.3 2.3 1.8e-24 85.3 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EPY53361.1 - 1.2e-19 69.7 0.5 2.3e-19 68.8 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPY53361.1 - 5.4e-06 26.5 0.4 4.7e-05 23.5 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPY53361.1 - 0.00032 20.4 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPY53361.1 - 0.0014 18.5 0.3 0.0027 17.5 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPY53361.1 - 0.012 15.7 0.4 0.016 15.4 0.3 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2318 PF10080.4 EPY53361.1 - 0.018 14.7 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DZR PF12773.2 EPY53361.1 - 0.023 14.4 0.3 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Plexin_cytopl PF08337.7 EPY53361.1 - 0.077 11.2 2.0 1.2 7.3 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 EPY53361.1 - 0.08 12.9 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) OrfB_Zn_ribbon PF07282.6 EPY53361.1 - 0.2 11.3 1.1 0.46 10.1 0.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EPY53361.1 - 0.39 10.0 2.5 0.85 8.9 1.7 1.6 1 1 0 1 1 1 0 zinc-ribbon domain RF-1 PF00472.15 EPY53362.1 - 1.5e-17 63.3 2.5 2.8e-17 62.5 1.8 1.4 1 0 0 1 1 1 1 RF-1 domain YicC_N PF03755.8 EPY53362.1 - 0.036 14.0 1.4 0.06 13.2 0.9 1.3 1 0 0 1 1 1 0 YicC-like family, N-terminal region Herpes_IE2_3 PF03361.9 EPY53362.1 - 0.13 11.5 2.1 0.19 11.0 1.1 1.5 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 MRP-S28 PF10213.4 EPY53362.1 - 0.15 12.1 5.9 0.71 9.9 3.1 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit protein Frag1 PF10277.4 EPY53363.1 - 6.2e-34 117.3 12.3 6.2e-34 117.3 8.6 2.7 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family POTRA_2 PF08479.6 EPY53363.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type Mis14 PF08641.7 EPY53364.1 - 1.8e-19 70.2 3.0 3.6e-19 69.1 0.6 2.3 1 1 2 3 3 3 1 Kinetochore protein Mis14 like Rota_Capsid_VP6 PF00980.12 EPY53364.1 - 0.066 11.8 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 DUF2115 PF09888.4 EPY53364.1 - 0.088 12.9 0.4 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) AMMECR1 PF01871.12 EPY53365.1 - 1.8e-41 141.1 0.0 2.2e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 GST_C PF00043.20 EPY53366.1 - 7.2e-06 25.9 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPY53366.1 - 6.1e-05 23.1 0.1 0.0046 17.0 0.0 2.9 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPY53366.1 - 0.00086 19.4 0.0 0.02 15.1 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPY53366.1 - 0.019 15.4 0.0 0.04 14.4 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPY53366.1 - 0.084 12.8 0.0 2.3 8.2 0.0 2.8 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Slx4 PF09494.5 EPY53367.1 - 3.2e-15 55.6 0.5 2.8e-14 52.6 0.0 2.5 3 0 0 3 3 3 1 Slx4 endonuclease Med12 PF09497.5 EPY53369.1 - 2.1e-21 75.6 0.3 8.2e-21 73.7 0.2 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DUF3169 PF11368.3 EPY53370.1 - 0.0055 15.9 0.2 0.0064 15.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) MFS_Mycoplasma PF07672.8 EPY53370.1 - 0.018 14.1 0.6 0.04 13.1 0.4 1.6 1 1 0 1 1 1 0 Mycoplasma MFS transporter TMEM154 PF15102.1 EPY53370.1 - 0.034 13.8 1.8 1.2 8.8 0.0 2.1 1 1 1 2 2 2 0 TMEM154 protein family DUF161 PF02588.10 EPY53370.1 - 0.05 13.8 0.3 0.066 13.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 DUF2663 PF10864.3 EPY53370.1 - 0.06 13.5 0.2 0.075 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Shisa PF13908.1 EPY53370.1 - 0.11 12.7 2.4 1.2 9.2 1.7 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3671 PF12420.3 EPY53370.1 - 0.11 12.5 4.0 0.14 12.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function SIT PF15330.1 EPY53370.1 - 0.15 12.2 0.8 1 9.5 0.0 2.2 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3139 PF11337.3 EPY53370.1 - 0.17 12.1 1.3 5.2 7.4 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3139) Mito_carr PF00153.22 EPY53372.1 - 8.8e-71 233.6 1.2 1.6e-23 82.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Epimerase PF01370.16 EPY53373.1 - 1.2e-23 83.7 0.1 3e-23 82.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY53373.1 - 3.5e-17 62.0 0.0 3.5e-17 62.0 0.0 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPY53373.1 - 1.2e-12 47.2 0.0 7.7e-12 44.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPY53373.1 - 1.3e-11 44.8 0.0 3.2e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPY53373.1 - 4.8e-08 33.0 0.3 1.1e-06 28.6 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPY53373.1 - 1.1e-07 31.0 0.5 1.9e-07 30.3 0.2 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EPY53373.1 - 1.9e-05 24.0 0.1 4.2e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 EPY53373.1 - 0.00013 21.6 0.1 0.0007 19.3 0.0 2.2 2 1 0 2 2 2 1 KR domain NAD_binding_2 PF03446.10 EPY53373.1 - 0.022 14.6 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.18 EPY53373.1 - 0.036 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 EPY53374.1 - 9.1e-21 74.3 0.0 3.2e-20 72.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY53374.1 - 6e-15 54.7 0.0 1.2e-14 53.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPY53374.1 - 8.2e-12 45.4 0.0 3.7e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPY53374.1 - 6.9e-11 41.5 0.0 3.8e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPY53374.1 - 3.7e-06 26.0 0.1 7.2e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPY53374.1 - 1.3e-05 25.2 0.2 0.00054 19.9 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EPY53374.1 - 7e-05 22.1 0.1 0.00038 19.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EPY53374.1 - 0.049 13.2 0.3 0.26 10.9 0.1 2.2 2 1 0 2 2 2 0 KR domain Ldh_1_N PF00056.18 EPY53374.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EPY53374.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DNA_pol_B PF00136.16 EPY53375.1 - 1.7e-99 333.7 0.1 3.4e-99 332.7 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPY53375.1 - 4.3e-31 107.9 0.3 8e-17 61.0 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPY53375.1 - 9.5e-10 38.3 11.4 3e-09 36.7 7.9 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF438 PF04282.8 EPY53375.1 - 0.031 14.0 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF438) ANTH PF07651.11 EPY53376.1 - 3.2e-74 249.1 0.0 3.2e-74 249.1 0.0 3.4 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.12 EPY53376.1 - 8.2e-62 207.6 8.2 8.2e-62 207.6 5.7 5.7 5 2 1 6 6 6 1 I/LWEQ domain zf-DHHC PF01529.15 EPY53377.1 - 4.1 6.7 5.5 8.9 5.6 2.7 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase TatD_DNase PF01026.16 EPY53378.1 - 2.7e-44 151.2 0.0 3.3e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase SET PF00856.23 EPY53379.1 - 7.6e-10 39.3 4.8 1.9e-09 38.0 2.0 2.4 2 1 1 3 3 3 2 SET domain DUF4499 PF14934.1 EPY53380.1 - 1.9e-07 30.9 2.2 2e-07 30.8 1.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) DUF420 PF04238.7 EPY53380.1 - 0.076 12.9 2.2 0.098 12.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Sybindin PF04099.7 EPY53381.1 - 4.2e-22 78.4 0.2 5.5e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Sybindin-like family Dev_Cell_Death PF10539.4 EPY53381.1 - 0.055 13.0 0.1 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Development and cell death domain Fcf2 PF08698.6 EPY53382.1 - 2.2e-34 117.3 0.3 6.1e-34 115.9 0.2 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing RFX_DNA_binding PF02257.10 EPY53383.1 - 5.6e-31 106.5 0.4 1.2e-30 105.4 0.3 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain tRNA-synt_1b PF00579.20 EPY53384.1 - 1.4e-75 254.1 0.0 1.8e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1829 PF08862.5 EPY53384.1 - 0.0058 16.8 3.3 1.1 9.5 2.6 3.0 2 1 0 2 2 2 1 Domain of unknown function DUF1829 CLASP_N PF12348.3 EPY53385.1 - 8e-76 254.3 13.1 2.2e-68 230.0 0.4 3.6 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 EPY53385.1 - 0.088 12.9 3.4 56 4.1 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat ACPS PF01648.15 EPY53387.1 - 6.1e-19 67.9 0.0 7e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RNase_PH PF01138.16 EPY53388.1 - 3e-33 114.9 0.0 4.6e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPY53388.1 - 3.2e-11 42.9 0.5 5.6e-10 39.0 0.2 2.2 1 1 1 2 2 2 2 3' exoribonuclease family, domain 2 DUF4242 PF14026.1 EPY53388.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) SH3_9 PF14604.1 EPY53390.1 - 1.8e-08 33.8 0.2 2.1e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPY53390.1 - 2.6e-08 33.1 0.0 3.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 SH3 domain EIF_2_alpha PF07541.7 EPY53391.1 - 3.8e-41 139.3 0.0 8.7e-41 138.2 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EPY53391.1 - 1.1e-11 44.6 2.5 2.1e-11 43.7 1.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain ING PF12998.2 EPY53392.1 - 7.4e-21 74.3 3.6 1.1e-20 73.8 2.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EPY53392.1 - 6.9e-10 38.4 9.2 1.1e-09 37.8 6.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPY53392.1 - 0.0038 16.5 3.1 0.0078 15.5 2.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EPY53392.1 - 0.005 16.9 1.1 0.005 16.9 0.7 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain Ribosomal_60s PF00428.14 EPY53392.1 - 0.018 15.4 2.4 0.043 14.2 1.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-HC5HC2H_2 PF13832.1 EPY53392.1 - 0.019 14.9 1.0 0.041 13.8 0.7 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 EPY53392.1 - 0.61 10.1 4.5 1.6 8.7 3.1 1.8 1 1 0 1 1 1 0 RING-like domain Hist_deacetyl PF00850.14 EPY53393.1 - 1.9e-80 270.4 0.1 2.4e-80 270.1 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Plasmod_MYXSPDY PF07981.6 EPY53393.1 - 0.068 12.8 0.7 0.31 10.7 0.2 2.1 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY tRNA-synt_2d PF01409.15 EPY53394.1 - 7.7e-90 300.4 0.0 1.1e-89 299.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPY53394.1 - 3.1e-06 26.8 0.0 9e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EPY53394.1 - 3.5e-05 22.7 3.2 0.00019 20.3 0.0 3.2 3 1 0 4 4 4 1 tRNA synthetases class II (D, K and N) HTH_45 PF14947.1 EPY53394.1 - 0.0085 15.8 1.2 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix Rio2_N PF09202.6 EPY53394.1 - 0.06 13.4 0.1 10 6.3 0.1 2.8 2 0 0 2 2 2 0 Rio2, N-terminal DWNN PF08783.6 EPY53394.1 - 0.1 12.5 0.5 3.2 7.7 0.0 2.8 3 0 0 3 3 3 0 DWNN domain GIT_SHD PF08518.6 EPY53395.1 - 2e-19 68.6 4.0 2.2e-10 39.6 1.2 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Fib_alpha PF08702.5 EPY53395.1 - 0.16 12.0 3.0 0.65 10.1 1.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ssu72 PF04722.8 EPY53396.1 - 4e-87 290.6 0.0 4.5e-87 290.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 EPY53396.1 - 0.042 14.1 0.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase DUF3857 PF12969.2 EPY53396.1 - 0.1 12.1 0.1 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Ribosomal_L14 PF00238.14 EPY53397.1 - 5e-35 119.9 0.0 5.6e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e adh_short_C2 PF13561.1 EPY53398.1 - 2.5e-27 96.1 0.1 3.1e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPY53398.1 - 5.1e-25 88.3 0.0 8e-25 87.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPY53398.1 - 7.2e-13 48.5 0.2 1.5e-12 47.5 0.1 1.5 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EPY53398.1 - 4.1e-11 42.7 0.5 2.3e-10 40.3 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPY53398.1 - 1.7e-08 33.6 0.0 2.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPY53398.1 - 1.2e-07 31.9 0.0 2.4e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EPY53398.1 - 8.7e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EPY53398.1 - 6.4e-05 21.9 0.2 0.00025 20.0 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.13 EPY53398.1 - 0.00057 19.5 0.1 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_4 PF13439.1 EPY53398.1 - 0.00079 19.1 0.0 0.071 12.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EPY53398.1 - 0.0023 18.0 0.8 0.26 11.4 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Saccharop_dh PF03435.13 EPY53398.1 - 0.013 14.5 0.1 0.029 13.3 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NmrA PF05368.8 EPY53398.1 - 0.046 12.9 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EPY53398.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.13 EPY53398.1 - 0.095 12.6 0.4 2.8 7.9 0.3 2.4 1 1 0 1 1 1 0 TrkA-N domain Sod_Fe_C PF02777.13 EPY53400.1 - 3.7e-34 116.7 2.0 6.1e-34 116.0 1.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPY53400.1 - 4.4e-28 97.3 0.8 8.8e-28 96.3 0.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain UBA PF00627.26 EPY53401.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain GCFC PF07842.7 EPY53402.1 - 5.1e-55 186.7 11.1 8.3e-55 186.0 7.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EPY53402.1 - 6.3e-16 57.8 0.8 1.4e-15 56.7 0.6 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPY53402.1 - 2.9e-09 36.6 0.7 9.1e-09 35.0 0.5 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site MRC1 PF09444.5 EPY53402.1 - 1.5 9.1 13.1 0.032 14.5 2.6 2.6 2 1 0 2 2 2 0 MRC1-like domain TMF_DNA_bd PF12329.3 EPY53403.1 - 0.00041 20.0 6.2 0.00041 20.0 4.3 21.5 12 5 9 22 22 22 6 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EPY53403.1 - 0.0031 17.2 17.0 0.0031 17.2 11.8 16.3 4 3 13 18 18 18 5 TPR/MLP1/MLP2-like protein Nup96 PF12110.3 EPY53404.1 - 4.5e-72 242.6 0.0 6.3e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EPY53404.1 - 2.2e-45 153.9 0.0 4e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EPY53404.1 - 7.6e-21 74.4 369.1 1.9e-06 28.1 23.0 10.4 3 2 7 10 10 10 6 Nucleoporin FG repeat region Complex1_LYR_2 PF13233.1 EPY53405.1 - 0.069 13.6 0.0 0.23 11.9 0.0 1.8 1 1 0 1 1 1 0 Complex1_LYR-like DDE_Tnp_ISAZ013 PF07592.6 EPY53405.1 - 0.13 10.9 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain NAPRTase PF04095.11 EPY53406.1 - 2.1e-65 220.4 0.7 2.7e-65 220.0 0.5 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Ribosomal_L11 PF00298.14 EPY53407.1 - 7.7e-26 90.0 0.3 1.7e-25 88.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EPY53407.1 - 1e-22 79.3 0.6 1.9e-22 78.4 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain COX16 PF14138.1 EPY53408.1 - 1.7e-20 72.9 0.2 2e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF1129 PF06570.6 EPY53410.1 - 0.28 10.4 2.2 0.42 9.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2244 PF10003.4 EPY53410.1 - 0.32 10.3 4.0 0.6 9.4 2.8 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF373 PF04123.8 EPY53410.1 - 0.34 9.9 2.4 0.54 9.2 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) FA_desaturase PF00487.19 EPY53410.1 - 1.1 8.6 11.1 1.5 8.1 7.6 1.4 1 1 0 1 1 1 0 Fatty acid desaturase HSP20 PF00011.16 EPY53411.1 - 6.8e-22 77.2 0.6 8.4e-22 76.9 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EPY53411.1 - 0.011 15.3 0.2 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) CS PF04969.11 EPY53411.1 - 0.031 14.8 0.5 0.068 13.7 0.1 1.7 2 0 0 2 2 2 0 CS domain Methyltransf_12 PF08242.7 EPY53412.1 - 0.12 12.8 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SUN PF03856.8 EPY53413.1 - 3.8e-98 327.7 14.6 5.2e-98 327.3 10.2 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) MSP1_C PF07462.6 EPY53413.1 - 3.2 6.0 4.1 4.4 5.5 2.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med3 PF11593.3 EPY53413.1 - 9 5.4 6.8 12 4.9 4.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aldedh PF00171.17 EPY53414.1 - 1.6e-158 527.8 0.1 2.4e-158 527.2 0.0 1.3 2 0 0 2 2 2 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EPY53414.1 - 0.0055 15.9 0.0 0.015 14.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Halo_GVPC PF05465.8 EPY53414.1 - 0.12 12.2 0.3 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Connexin43 PF03508.8 EPY53414.1 - 0.15 11.3 1.2 0.26 10.5 0.8 1.4 1 0 0 1 1 1 0 Gap junction alpha-1 protein (Cx43) Gaa1 PF04114.9 EPY53415.1 - 3.3e-112 375.7 17.0 6.9e-110 368.1 1.3 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component SGT1 PF07093.6 EPY53416.1 - 2e-104 350.1 29.5 2.4e-94 316.8 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein Pyr_redox_dim PF02852.17 EPY53417.1 - 3.4e-41 139.7 1.7 5e-41 139.1 0.2 2.1 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EPY53417.1 - 1.4e-38 132.8 0.0 3.1e-38 131.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPY53417.1 - 2.4e-18 66.3 3.9 3.4e-17 62.6 0.2 3.1 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPY53417.1 - 2.6e-11 43.2 0.4 1.8e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPY53417.1 - 1.7e-09 37.5 1.9 0.00045 20.1 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPY53417.1 - 8.8e-08 32.4 0.2 3.1e-05 24.1 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPY53417.1 - 5.8e-06 25.3 1.6 5.9e-05 22.1 0.4 2.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EPY53417.1 - 9.7e-06 24.6 11.9 0.0004 19.3 8.2 3.2 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EPY53417.1 - 7.7e-05 21.8 7.9 0.064 12.2 0.3 3.8 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EPY53417.1 - 0.00014 21.0 5.7 0.00039 19.6 0.2 2.4 1 1 1 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EPY53417.1 - 0.00039 19.4 0.0 0.061 12.2 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EPY53417.1 - 0.00055 18.5 8.3 0.043 12.2 0.1 3.8 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 EPY53417.1 - 0.036 13.6 0.3 0.25 10.8 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EPY53417.1 - 0.055 13.1 0.7 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EPY53417.1 - 0.23 10.3 10.4 4 6.2 0.6 3.4 2 2 0 3 3 3 0 FAD dependent oxidoreductase RrnaAD PF00398.15 EPY53418.1 - 4.6e-39 134.0 0.0 5.6e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TetR_N PF00440.18 EPY53418.1 - 0.04 13.5 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Acetyltransf_1 PF00583.19 EPY53419.1 - 4.3e-15 55.5 0.0 6.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY53419.1 - 1.5e-10 41.0 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPY53419.1 - 8.6e-07 29.0 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY53419.1 - 2.7e-06 27.0 0.0 4.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EPY53419.1 - 0.00016 21.8 0.0 0.0002 21.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPY53419.1 - 0.0039 17.1 0.0 0.0052 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY53419.1 - 0.071 12.9 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SPDY PF03771.11 EPY53420.1 - 0.14 11.6 0.8 2.9 7.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF317) JmjC PF02373.17 EPY53421.1 - 6.2e-40 136.0 0.1 1.8e-39 134.5 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EPY53421.1 - 2e-14 52.8 1.6 6.6e-14 51.1 1.1 2.0 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EPY53421.1 - 4.8e-12 45.7 9.4 1.5e-11 44.1 6.5 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger ARID PF01388.16 EPY53421.1 - 4.6e-06 26.3 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain KLRAQ PF10205.4 EPY53421.1 - 8.8 6.4 10.1 0.2 11.7 0.3 2.8 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein TAFII28 PF04719.9 EPY53422.1 - 3.4e-36 122.8 0.0 5.5e-36 122.2 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Glyco_hydro_31 PF01055.21 EPY53423.1 - 2.9e-145 484.4 0.3 3.9e-145 484.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPY53423.1 - 1.8e-22 78.9 0.3 5e-22 77.5 0.2 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like NPCC PF08058.6 EPY53424.1 - 1.5e-22 80.0 0.0 8e-14 51.7 0.0 2.3 1 1 1 2 2 2 2 Nuclear pore complex component Spore_III_AF PF09581.5 EPY53424.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) CytochromB561_N PF09786.4 EPY53424.1 - 0.026 12.9 3.0 0.052 12.0 0.0 2.1 2 0 0 2 2 2 0 Cytochrome B561, N terminal FLILHELTA PF10306.4 EPY53426.1 - 4.2e-22 77.9 0.0 6.2e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA IncA PF04156.9 EPY53427.1 - 0.083 12.4 4.9 0.29 10.7 0.4 2.6 2 0 0 2 2 2 0 IncA protein RRM_1 PF00076.17 EPY53428.1 - 1.3e-33 114.4 1.7 1.1e-14 53.7 0.0 4.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53428.1 - 6.8e-27 93.2 0.3 4.2e-08 33.0 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53428.1 - 1.3e-16 60.1 3.7 3.6e-08 33.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L1 PF00687.16 EPY53429.1 - 1e-21 77.3 0.0 1.2e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Voldacs PF03517.8 EPY53430.1 - 9.6e-23 80.5 1.3 1.1e-21 77.1 0.9 2.1 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Hid1 PF12722.2 EPY53431.1 - 6.9e-141 470.7 24.9 8.5e-141 470.4 17.2 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EPY53431.1 - 1.4e-58 198.5 0.0 6.6e-58 196.3 0.0 1.9 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein tRNA-synt_1c PF00749.16 EPY53432.1 - 1.8e-103 345.5 0.0 2.5e-103 345.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPY53432.1 - 4.4e-42 143.6 0.9 9e-42 142.6 0.6 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EPY53432.1 - 3.6e-08 33.7 0.1 1.1e-07 32.2 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPY53432.1 - 0.00012 21.9 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EPY53432.1 - 0.021 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C_2 PF13410.1 EPY53432.1 - 0.11 12.4 0.3 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain XRN_N PF03159.13 EPY53433.1 - 5.4e-105 350.0 0.0 8.5e-105 349.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus EF-hand_6 PF13405.1 EPY53433.1 - 0.036 13.9 0.2 0.15 12.0 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain GTP_cyclohydroI PF01227.17 EPY53434.1 - 2.4e-75 251.7 0.1 2.9e-75 251.4 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EPY53434.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein OmpH PF03938.9 EPY53434.1 - 0.0076 16.1 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) Sox_N PF12444.3 EPY53434.1 - 0.092 13.8 0.0 0.22 12.6 0.0 1.7 1 0 0 1 1 1 0 Sox developmental protein N terminal TPR_11 PF13414.1 EPY53435.1 - 3.7e-14 52.1 0.2 1.1e-11 44.2 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EPY53435.1 - 2.6e-10 39.4 0.0 0.00057 19.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY53435.1 - 7.3e-10 38.0 0.2 0.0013 18.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPY53435.1 - 8.2e-09 34.6 1.9 0.079 12.7 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53435.1 - 4.7e-08 32.8 0.1 7.9e-06 25.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 EPY53435.1 - 0.00018 21.2 0.0 0.00053 19.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.26 EPY53435.1 - 0.0024 17.6 0.0 0.0073 16.1 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain TPR_16 PF13432.1 EPY53435.1 - 0.013 16.1 0.0 15 6.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.2 EPY53435.1 - 0.04 13.7 0.4 0.16 11.8 0.1 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TP6A_N PF04406.9 EPY53436.1 - 1.3e-21 76.0 0.0 2.4e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EPY53436.1 - 0.0011 18.7 0.0 0.003 17.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) DnaJ_CXXCXGXG PF00684.14 EPY53437.1 - 0.069 13.2 10.9 0.47 10.5 1.6 2.5 2 1 0 2 2 2 0 DnaJ central domain IPP-2 PF04979.9 EPY53438.1 - 3.7e-06 27.2 3.9 1.5e-05 25.2 1.0 3.4 3 1 1 4 4 4 2 Protein phosphatase inhibitor 2 (IPP-2) EMP24_GP25L PF01105.19 EPY53439.1 - 6.4e-40 136.8 2.1 7.4e-40 136.6 1.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4302 PF14135.1 EPY53439.1 - 0.0052 16.1 0.3 0.0067 15.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4302) Peptidase_C48 PF02902.14 EPY53440.1 - 2.8e-50 170.9 1.8 4.2e-50 170.3 1.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RMF PF04957.7 EPY53440.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosome modulation factor Helicase_C_3 PF13625.1 EPY53441.1 - 1.8e-29 102.0 0.0 9.3e-29 99.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY53441.1 - 1.1e-14 54.6 0.0 2.6e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPY53441.1 - 1.4e-11 43.7 0.2 2.4e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY53441.1 - 2.1e-10 40.3 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY53441.1 - 2.7e-06 26.9 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 EPY53441.1 - 0.12 11.7 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Methyltransf_23 PF13489.1 EPY53443.1 - 1.9e-07 30.9 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY53443.1 - 9.7e-05 21.9 0.0 0.075 12.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EPY53443.1 - 0.00011 22.6 0.0 0.00042 20.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY53443.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY53443.1 - 0.0016 18.8 0.0 0.013 15.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY53443.1 - 0.013 15.8 0.1 0.13 12.6 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EPY53443.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Reprolysin_5 PF13688.1 EPY53444.1 - 4.4e-25 88.7 0.0 4.4e-25 88.7 0.0 3.0 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EPY53444.1 - 8.7e-23 80.9 0.0 4.4e-22 78.6 0.0 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EPY53444.1 - 1e-18 68.0 0.0 2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EPY53444.1 - 3.2e-18 65.7 31.9 3.2e-18 65.7 22.1 4.3 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 EPY53444.1 - 2.1e-06 27.4 0.5 2.1e-06 27.4 0.3 3.4 2 1 1 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_3 PF13582.1 EPY53444.1 - 2.3e-05 24.9 0.0 6.8e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EPY53444.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 EPY53444.1 - 0.11 12.1 0.1 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.6 EPY53444.1 - 0.13 11.9 0.7 0.46 10.2 0.5 1.9 1 0 0 1 1 1 0 Peptidase family M54 Ribosomal_L3 PF00297.17 EPY53445.1 - 2.1e-120 401.0 6.7 2.5e-120 400.7 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DBR1 PF05011.8 EPY53446.1 - 5.7e-36 123.5 0.3 1.6e-35 122.1 0.1 1.7 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EPY53446.1 - 2.4e-12 46.6 0.4 3.6e-12 46.0 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EPY53446.1 - 0.0056 15.8 0.0 0.023 13.8 0.0 1.9 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily AAA PF00004.24 EPY53447.1 - 3.3e-52 176.1 0.0 3.9e-45 153.2 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPY53447.1 - 2.6e-05 23.3 0.0 6.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EPY53447.1 - 6.3e-05 23.7 0.1 0.0005 20.8 0.0 2.7 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 EPY53447.1 - 0.00012 22.1 0.5 0.00067 19.6 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY53447.1 - 0.00012 22.1 0.3 0.0051 16.9 0.0 3.0 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.8 EPY53447.1 - 0.00055 18.7 0.0 0.001 17.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EPY53447.1 - 0.00072 19.3 0.1 0.0033 17.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPY53447.1 - 0.00088 19.4 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 EPY53447.1 - 0.0023 17.3 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EPY53447.1 - 0.0024 17.5 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 EPY53447.1 - 0.004 17.0 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPY53447.1 - 0.0048 16.7 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPY53447.1 - 0.0051 16.2 0.7 0.14 11.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EPY53447.1 - 0.0074 16.1 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPY53447.1 - 0.011 14.8 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EPY53447.1 - 0.012 15.2 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPY53447.1 - 0.013 15.7 0.1 0.056 13.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.6 EPY53447.1 - 0.018 14.6 0.0 0.045 13.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPY53447.1 - 0.037 13.9 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain KaiC PF06745.8 EPY53447.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EPY53447.1 - 0.077 12.2 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EPY53447.1 - 0.092 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EPY53447.1 - 0.11 11.5 0.1 0.41 9.7 0.0 1.9 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 EPY53447.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPY53447.1 - 0.12 12.0 0.1 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EPY53447.1 - 0.17 11.3 0.0 0.41 10.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RHH_3 PF12651.2 EPY53447.1 - 0.32 10.7 2.4 17 5.2 0.1 3.4 3 0 0 3 3 3 0 Ribbon-helix-helix domain CDC37_N PF03234.9 EPY53448.1 - 1.2 9.4 7.0 1.5 9.1 4.8 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Fungal_trans PF04082.13 EPY53449.1 - 3.3e-25 88.4 5.1 6.3e-25 87.5 3.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_4 PF13637.1 EPY53451.1 - 1.4e-12 47.7 0.5 8e-07 29.4 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPY53451.1 - 4.6e-12 46.1 1.8 1e-09 38.5 0.2 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPY53451.1 - 6.9e-10 38.8 0.7 6.3e-05 23.0 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EPY53451.1 - 5.5e-09 35.4 1.4 0.0005 19.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EPY53451.1 - 3.8e-06 26.6 0.3 0.16 12.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Na_H_Exchanger PF00999.16 EPY53452.1 - 1.3e-62 211.5 42.9 2e-62 210.9 29.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SFTA2 PF15210.1 EPY53452.1 - 0.025 14.1 1.0 2.1 8.0 0.0 3.3 2 1 0 2 2 2 0 Surfactant-associated protein 2 Pkinase PF00069.20 EPY53453.1 - 1.9e-71 240.2 0.0 2.2e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53453.1 - 2.6e-33 115.2 0.0 3.3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY53453.1 - 1.4e-06 27.5 0.0 2.1e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPY53453.1 - 0.00056 19.7 0.0 0.025 14.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EPY53453.1 - 0.00092 18.6 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EPY53453.1 - 0.0018 17.3 0.0 0.0033 16.5 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EPY53454.1 - 1.8e-46 154.4 7.8 1e-09 37.9 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPY53454.1 - 3.2e-09 35.5 11.2 0.0098 14.0 0.4 5.2 3 2 2 5 5 5 4 Nucleoporin Nup120/160 APG6 PF04111.7 EPY53454.1 - 0.012 14.6 1.9 0.019 14.0 1.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ICAP-1_inte_bdg PF10480.4 EPY53454.1 - 0.015 15.0 0.2 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 Beta-1 integrin binding protein Ammonium_transp PF00909.16 EPY53455.1 - 2.3e-114 381.9 29.0 2.7e-114 381.7 20.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Glyco_tranf_2_5 PF13712.1 EPY53456.1 - 0.063 12.5 0.3 0.081 12.1 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family YfbU PF03887.9 EPY53456.1 - 0.15 11.5 3.7 0.39 10.2 2.6 1.7 1 1 0 1 1 1 0 YfbU domain COG2 PF06148.6 EPY53456.1 - 0.2 11.4 5.1 0.45 10.3 3.5 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4637 PF15470.1 EPY53456.1 - 0.24 10.9 6.9 0.3 10.6 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) GTP_EFTU PF00009.22 EPY53456.1 - 0.69 9.3 3.4 1 8.7 2.3 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Tom37_C PF11801.3 EPY53456.1 - 1.6 8.5 7.3 1.8 8.3 5.1 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF3154 PF11351.3 EPY53456.1 - 2.5 7.8 7.2 0.6 9.8 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) ICA69 PF04629.9 EPY53456.1 - 2.9 7.7 9.4 3.3 7.5 6.5 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Vfa1 PF08432.5 EPY53456.1 - 5.2 7.0 14.4 5.4 6.9 10.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Histone_HNS PF00816.16 EPY53456.1 - 7.1 7.2 10.9 7.8 7.0 5.6 2.0 1 1 1 2 2 2 0 H-NS histone family Pox_RNA_Pol_19 PF05320.7 EPY53456.1 - 9.6 5.9 11.8 11 5.7 8.0 1.3 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Complex1_LYR PF05347.10 EPY53457.1 - 4.6e-09 35.9 3.3 6.6e-09 35.4 2.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPY53457.1 - 8.4e-07 29.1 3.1 1.1e-06 28.7 2.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like HSP70 PF00012.15 EPY53458.1 - 5.5e-260 863.4 9.2 6.3e-260 863.2 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPY53458.1 - 5.1e-14 51.6 2.7 1.1e-12 47.2 0.4 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EPY53458.1 - 0.0016 18.2 3.8 0.6 9.9 0.0 3.9 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 EPY53458.1 - 0.0039 16.8 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EPY53458.1 - 0.0051 15.7 0.4 0.098 11.5 0.0 2.3 1 1 0 2 2 2 1 StbA protein Kinesin PF00225.18 EPY53459.1 - 6e-103 344.0 0.2 6e-103 344.0 0.1 2.1 2 1 1 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EPY53459.1 - 0.0047 16.1 7.0 0.0047 16.1 4.9 3.0 3 0 0 3 3 3 1 Reovirus sigma C capsid protein DUF3584 PF12128.3 EPY53459.1 - 2.3 5.4 40.4 3.4 4.8 28.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) G_glu_transpept PF01019.16 EPY53460.1 - 2.2e-169 564.2 0.0 2.6e-169 564.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Actin PF00022.14 EPY53461.1 - 4.2e-31 107.7 0.0 3e-30 104.9 0.0 2.2 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPY53461.1 - 0.00081 18.0 0.0 1.1 7.7 0.0 2.4 3 0 0 3 3 3 2 MreB/Mbl protein PilM_2 PF11104.3 EPY53461.1 - 0.027 13.3 0.0 0.79 8.5 0.0 2.2 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Paf1 PF03985.8 EPY53462.1 - 1.6e-97 327.0 6.1 1.6e-97 327.0 4.2 2.0 1 1 1 2 2 2 1 Paf1 Ribosomal_S9 PF00380.14 EPY53463.1 - 6.7e-38 129.6 0.5 7.6e-38 129.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Exo70 PF03081.10 EPY53463.1 - 0.18 10.5 0.3 0.23 10.2 0.2 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Ribosomal_L13e PF01294.13 EPY53464.1 - 9.4e-71 236.9 4.8 1.2e-70 236.6 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L30_N PF08079.7 EPY53465.1 - 2.1e-19 69.3 11.4 2.1e-19 69.3 7.9 2.2 3 0 0 3 3 3 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EPY53465.1 - 1.3e-17 63.0 1.6 2.9e-17 61.9 0.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rad9 PF04139.8 EPY53466.1 - 8.9e-91 303.4 4.4 1.1e-90 303.1 3.0 1.1 1 0 0 1 1 1 1 Rad9 TRAUB PF08164.7 EPY53467.1 - 1.8e-28 98.4 0.3 1.8e-28 98.4 0.2 3.3 4 0 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EPY53467.1 - 1.6e-21 76.7 3.6 1.6e-21 76.7 2.5 3.9 3 2 1 4 4 4 1 Apoptosis antagonizing transcription factor Chromo_shadow PF01393.14 EPY53468.1 - 1.1e-27 95.5 0.1 1e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 EPY53468.1 - 8.5e-14 50.9 1.1 8.5e-14 50.9 0.8 3.0 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain TEBP_beta PF07404.6 EPY53468.1 - 1.6 7.7 9.8 2.4 7.2 6.8 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) ArfGap PF01412.13 EPY53469.1 - 4.8e-41 139.2 0.4 9.4e-41 138.2 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Herpes_BLLF1 PF05109.8 EPY53469.1 - 1.2 7.0 16.3 1.4 6.7 11.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Adap_comp_sub PF00928.16 EPY53470.1 - 2.9e-79 265.8 0.2 3.8e-79 265.4 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPY53470.1 - 9.3e-14 51.3 0.3 2e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L23 PF00276.15 EPY53471.1 - 5.1e-20 71.2 0.0 8e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 DEAD PF00270.24 EPY53472.1 - 3.8e-48 163.1 0.1 1.5e-47 161.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY53472.1 - 4.5e-22 77.6 0.2 8.9e-21 73.5 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EPY53472.1 - 1.4e-20 72.8 0.9 3.5e-20 71.5 0.6 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Oligomerisation PF02410.10 EPY53473.1 - 1.4e-10 41.1 0.1 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Oligomerisation domain Nipped-B_C PF12830.2 EPY53474.1 - 5.4e-44 150.0 4.2 5.4e-44 150.0 2.9 3.1 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EPY53474.1 - 2.8e-07 30.3 7.3 3.9e-06 26.6 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EPY53474.1 - 0.00063 19.6 0.1 41 4.6 0.0 5.6 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.1 EPY53474.1 - 0.0042 17.3 0.0 0.65 10.3 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats Proteasome PF00227.21 EPY53475.1 - 1.5e-36 125.4 0.0 1.8e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L10 PF00466.15 EPY53476.1 - 0.00035 20.4 0.0 0.00081 19.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L10 Trm112p PF03966.11 EPY53477.1 - 2.4e-18 66.2 0.2 2.9e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 EPY53477.1 - 0.14 11.7 0.2 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DUF3133 PF11331.3 EPY53477.1 - 0.15 11.6 0.8 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) PCI PF01399.22 EPY53478.1 - 6.1e-13 49.0 0.1 6.1e-13 49.0 0.1 2.6 2 1 1 3 3 3 1 PCI domain P16-Arc PF04699.9 EPY53478.1 - 0.038 14.0 0.8 0.64 10.0 0.2 2.5 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Ribosomal_S19 PF00203.16 EPY53479.1 - 7.6e-24 83.1 0.0 9.2e-24 82.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Dzip-like_N PF13815.1 EPY53480.1 - 0.00026 20.7 1.0 0.00092 18.9 0.6 1.9 1 1 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal SR-25 PF10500.4 EPY53480.1 - 0.035 13.5 11.5 0.049 13.0 8.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MOR2-PAG1_N PF14222.1 EPY53480.1 - 0.19 10.3 5.1 0.21 10.2 3.5 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Ribosomal_60s PF00428.14 EPY53480.1 - 2 8.8 8.9 5.5 7.4 6.1 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein Gti1_Pac2 PF09729.4 EPY53481.1 - 7.5e-56 188.6 0.0 2.5e-55 186.8 0.0 1.9 1 1 0 1 1 1 1 Gti1/Pac2 family WD40 PF00400.27 EPY53482.1 - 4.5e-75 245.0 13.3 1.3e-12 47.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EPY53482.1 - 5e-26 90.7 11.2 8.1e-26 90.0 7.8 1.3 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 EPY53482.1 - 2.8e-09 36.2 6.3 8.6e-07 28.0 1.0 3.6 1 1 1 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 EPY53482.1 - 3.9e-06 26.4 5.0 3.5 7.4 0.0 7.1 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EPY53482.1 - 6e-06 26.1 0.0 0.0068 16.1 0.0 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EPY53482.1 - 0.0053 15.0 0.1 0.22 9.8 0.0 2.5 1 1 0 2 2 2 1 Cytochrome D1 heme domain DUF3312 PF11768.3 EPY53482.1 - 0.08 11.1 0.0 13 3.8 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3312) Prefoldin_2 PF01920.15 EPY53482.1 - 0.3 10.8 7.0 0.068 12.9 2.4 1.6 2 0 0 2 2 2 0 Prefoldin subunit DUF3384 PF11864.3 EPY53483.1 - 2.8e-54 184.3 13.3 2.8e-54 184.3 9.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EPY53483.1 - 2.6e-52 176.9 0.3 6.3e-52 175.6 0.2 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EPY53483.1 - 3.8e-24 85.4 6.7 9.2e-24 84.1 2.0 3.1 3 1 0 3 3 3 1 Tuberin Metallophos PF00149.23 EPY53484.1 - 7.6e-12 45.0 0.8 1.4e-11 44.2 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2317 PF10079.4 EPY53484.1 - 0.032 12.8 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Vps55 PF04133.9 EPY53485.1 - 6.2e-37 125.9 3.7 7e-37 125.8 2.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Oxidored_q1 PF00361.15 EPY53485.1 - 6.9e-05 22.2 1.4 0.00014 21.2 0.6 1.7 1 1 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Wzy_C PF04932.10 EPY53485.1 - 1.1 9.0 4.6 8.4 6.1 1.4 2.1 2 0 0 2 2 2 0 O-Antigen ligase Peptidase_M50B PF13398.1 EPY53485.1 - 1.1 8.5 6.5 1.1 8.6 0.3 2.1 2 0 0 2 2 2 0 Peptidase M50B-like DUF3321 PF11968.3 EPY53486.1 - 8.6e-68 228.2 0.0 1.1e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) PGK PF00162.14 EPY53487.1 - 1.6e-148 494.3 1.7 1.8e-148 494.2 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase HEAT PF02985.17 EPY53488.1 - 3e-25 85.9 1.4 0.00011 21.9 0.1 11.1 11 0 0 11 11 10 4 HEAT repeat HEAT_EZ PF13513.1 EPY53488.1 - 8.8e-22 76.9 2.3 0.00022 21.6 0.1 9.1 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 EPY53488.1 - 2.5e-16 59.6 5.1 0.0043 17.2 0.1 8.2 6 2 4 10 10 10 5 HEAT repeats Vac14_Fab1_bd PF12755.2 EPY53488.1 - 3.3e-11 43.4 0.5 0.076 13.4 0.0 6.2 4 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EPY53488.1 - 2.1e-10 40.3 0.8 5e-08 32.7 0.1 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.3 EPY53488.1 - 3.7e-08 32.5 11.8 1.6e-06 27.1 0.1 4.5 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 EPY53488.1 - 2.1e-06 27.6 2.3 0.096 12.5 0.1 5.4 5 3 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EPY53488.1 - 3.7e-06 26.8 0.0 0.45 10.4 0.0 5.0 4 1 1 5 5 5 2 UME (NUC010) domain Ipi1_N PF12333.3 EPY53488.1 - 0.0001 22.2 0.3 0.14 12.1 0.1 4.3 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.3 EPY53488.1 - 0.00019 20.8 0.1 4 6.7 0.0 5.3 4 2 1 5 5 5 1 CLASP N terminal Anticodon_1 PF08264.8 EPY53488.1 - 0.0041 16.8 0.1 1 9.0 0.0 3.5 4 0 0 4 4 4 1 Anticodon-binding domain of tRNA DUF2435 PF10363.4 EPY53488.1 - 0.1 12.5 0.9 18 5.3 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Trs65 PF12735.2 EPY53489.1 - 6.4e-23 81.5 0.5 6.4e-23 81.5 0.3 1.8 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 DUF4504 PF14953.1 EPY53490.1 - 3.3e-09 36.4 1.1 7.9e-08 31.9 0.9 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) Pkinase PF00069.20 EPY53491.1 - 2.2e-68 230.2 0.0 3.5e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53491.1 - 2.2e-31 108.8 0.1 6.8e-30 104.0 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY53491.1 - 2.4e-06 26.7 0.6 0.00036 19.6 0.0 3.0 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EPY53491.1 - 0.026 14.2 0.0 5.4 6.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EPY53491.1 - 0.033 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.1 EPY53492.1 - 8.1e-42 142.7 0.1 1.1e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EPY53492.1 - 1.1e-10 40.8 1.9 9.5e-05 21.9 0.9 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPY53492.1 - 6.2e-07 29.0 4.4 1.2e-06 28.1 0.1 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPY53492.1 - 0.01 15.7 2.5 10 6.5 0.2 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat GGDEF PF00990.16 EPY53492.1 - 0.054 13.0 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 GGDEF domain LRR_7 PF13504.1 EPY53492.1 - 0.14 12.4 4.4 5 7.7 0.9 3.8 2 1 1 3 3 3 0 Leucine rich repeat Skp1_POZ PF03931.10 EPY53493.1 - 2.2e-14 53.2 0.0 3.6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain UPF0300 PF08594.5 EPY53494.1 - 1.1e-59 200.9 0.6 1.6e-59 200.4 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Indigoidine_A PF04227.7 EPY53495.1 - 4.7e-126 419.9 0.1 6.3e-126 419.5 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EPY53495.1 - 2e-22 79.7 0.0 1.8e-21 76.5 0.0 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPY53495.1 - 0.0022 17.2 0.0 0.058 12.5 0.0 2.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase RRM_1 PF00076.17 EPY53496.1 - 3e-48 161.3 1.3 6.3e-13 48.1 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53496.1 - 1.3e-45 153.2 0.3 4.2e-13 49.0 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53496.1 - 1.3e-23 82.5 0.1 4.9e-07 29.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EPY53496.1 - 0.0029 16.9 1.0 0.0072 15.7 0.7 1.7 1 0 0 1 1 1 1 Lsm interaction motif Mak10 PF04112.8 EPY53497.1 - 2.3e-40 137.5 0.1 4.6e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Kinesin PF00225.18 EPY53497.1 - 0.066 11.8 0.1 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain Abp2 PF09441.5 EPY53498.1 - 7.9e-68 227.8 0.2 1.3e-67 227.1 0.1 1.3 1 0 0 1 1 1 1 ARS binding protein 2 RTBV_P46 PF06216.6 EPY53498.1 - 0.0086 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein DUF2730 PF10805.3 EPY53498.1 - 0.016 14.9 0.1 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF904 PF06005.7 EPY53498.1 - 0.018 15.3 1.4 0.056 13.7 1.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EPY53498.1 - 0.055 12.9 0.2 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator AT_hook PF02178.14 EPY53498.1 - 5.2 7.0 8.5 11 6.1 5.9 1.5 1 0 0 1 1 1 0 AT hook motif CENP-C_C PF11699.3 EPY53499.1 - 4e-25 87.6 0.0 1.5e-24 85.8 0.0 2.0 2 1 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.6 EPY53499.1 - 0.0015 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.14 EPY53499.1 - 0.034 13.8 15.5 0.72 9.7 1.9 3.1 2 0 0 2 2 2 0 AT hook motif Mif2_N PF15624.1 EPY53499.1 - 0.54 10.8 39.3 43 4.6 22.0 4.4 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal MRP_L53 PF10780.4 EPY53500.1 - 1.5e-14 53.6 0.1 2.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 F-box-like PF12937.2 EPY53501.1 - 9.7e-09 34.8 0.7 2e-08 33.8 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPY53501.1 - 3.9e-08 32.7 0.6 9.5e-08 31.5 0.4 1.7 1 0 0 1 1 1 1 F-box domain Ribosomal_L19e PF01280.15 EPY53502.1 - 1.9e-61 206.1 9.4 1.9e-61 206.1 6.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e DUF3035 PF11233.3 EPY53502.1 - 1.5 8.8 5.6 0.98 9.4 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Actin PF00022.14 EPY53503.1 - 3.4e-17 61.9 0.0 1.7e-16 59.6 0.0 1.8 1 1 0 1 1 1 1 Actin RICTOR_M PF14666.1 EPY53503.1 - 0.068 12.1 0.4 0.11 11.4 0.3 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain DRIM PF07539.7 EPY53504.1 - 8.3e-40 135.4 4.6 1.9e-38 131.0 0.1 4.5 4 0 0 4 4 4 1 Down-regulated in metastasis Zn_clus PF00172.13 EPY53505.1 - 0.00011 22.0 12.2 0.00033 20.5 8.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 EPY53506.1 - 9 4.1 12.8 10 4.0 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein PRP1_N PF06424.7 EPY53506.1 - 9.1 6.6 12.4 11 6.3 8.6 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal rve PF00665.21 EPY53508.1 - 0.059 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain AAA PF00004.24 EPY53511.1 - 4.3e-91 301.9 0.0 1.2e-44 151.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPY53511.1 - 3.3e-13 49.8 0.0 5e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPY53511.1 - 4e-12 45.6 0.0 7.7e-05 21.8 0.0 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPY53511.1 - 4.5e-12 45.8 0.1 6e-06 26.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPY53511.1 - 5.1e-12 46.1 0.2 2.2e-05 24.5 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EPY53511.1 - 9.8e-11 41.9 4.8 0.00016 21.7 0.0 5.2 4 2 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EPY53511.1 - 1.2e-09 39.0 0.2 4e-05 24.4 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPY53511.1 - 1e-08 34.8 4.9 0.095 12.0 0.0 4.4 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.1 EPY53511.1 - 1.1e-07 31.8 0.0 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EPY53511.1 - 2e-06 26.9 0.0 0.0037 16.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EPY53511.1 - 2.2e-06 26.9 0.0 0.015 14.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EPY53511.1 - 2.5e-06 27.1 0.2 0.0042 16.7 0.0 3.4 3 0 0 3 3 2 1 Part of AAA domain TIP49 PF06068.8 EPY53511.1 - 5.4e-06 25.3 0.0 0.039 12.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 EPY53511.1 - 7.4e-06 25.8 0.0 0.12 12.0 0.0 3.8 2 2 1 3 3 3 1 Archaeal ATPase AAA_33 PF13671.1 EPY53511.1 - 1.6e-05 24.8 0.0 0.01 15.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EPY53511.1 - 2.5e-05 24.3 0.1 0.012 15.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 EPY53511.1 - 3.3e-05 23.3 0.0 0.079 12.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EPY53511.1 - 3.9e-05 23.7 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EPY53511.1 - 6.4e-05 22.2 0.4 0.081 12.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPY53511.1 - 8.9e-05 22.1 0.0 0.21 11.1 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EPY53511.1 - 0.00019 21.7 0.0 0.085 13.1 0.0 2.9 3 0 0 3 3 2 1 ABC transporter Bac_DnaA PF00308.13 EPY53511.1 - 0.00028 20.5 0.0 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.10 EPY53511.1 - 0.00034 19.4 0.0 0.01 14.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EPY53511.1 - 0.00084 19.0 0.8 0.23 11.1 0.0 3.9 4 0 0 4 4 4 1 NACHT domain AAA_11 PF13086.1 EPY53511.1 - 0.00089 18.8 0.0 0.034 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPY53511.1 - 0.0028 17.9 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EPY53511.1 - 0.0053 16.7 0.0 3.4 7.7 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 EPY53511.1 - 0.0057 17.0 0.6 0.027 14.7 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPY53511.1 - 0.0074 15.8 0.8 0.42 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EPY53511.1 - 0.0091 15.5 3.7 0.045 13.3 0.0 3.0 4 1 0 4 4 2 1 AAA domain Beta_protein PF14350.1 EPY53511.1 - 0.011 14.8 0.0 0.087 11.9 0.0 2.0 2 0 0 2 2 2 0 Beta protein CDC48_N PF02359.13 EPY53511.1 - 0.016 15.1 0.0 0.058 13.3 0.0 2.0 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain NTPase_1 PF03266.10 EPY53511.1 - 0.017 14.8 0.5 1.7 8.3 0.0 3.7 3 2 2 5 5 4 0 NTPase Sigma54_activat PF00158.21 EPY53511.1 - 0.018 14.5 0.0 7.7 5.9 0.0 3.8 3 1 0 3 3 3 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EPY53511.1 - 0.028 13.2 0.1 0.31 9.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.9 EPY53511.1 - 0.031 13.2 0.0 0.48 9.3 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain MMR_HSR1 PF01926.18 EPY53511.1 - 0.072 13.0 0.0 0.46 10.4 0.0 2.2 1 1 1 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 EPY53511.1 - 0.11 12.0 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EPY53511.1 - 0.13 11.3 0.7 14 4.7 0.0 3.2 3 1 1 4 4 3 0 KaiC AAA_29 PF13555.1 EPY53511.1 - 0.14 11.7 0.0 4.2 6.9 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain PUF PF00806.14 EPY53513.1 - 8.1e-17 59.6 0.3 0.00038 19.7 0.0 5.6 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EPY53513.1 - 1.2e-06 28.0 0.0 2.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53513.1 - 0.00011 22.0 0.0 0.00046 19.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53513.1 - 0.0019 18.1 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CPSase_sm_chain PF00988.17 EPY53514.1 - 2.4e-45 153.2 0.0 4e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EPY53514.1 - 7.2e-45 152.8 0.0 9.9e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPY53514.1 - 0.00028 20.4 1.8 0.07 12.5 1.2 2.8 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EPY53514.1 - 0.0056 16.1 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.17 EPY53514.1 - 0.17 10.3 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 DUF1470 PF07336.6 EPY53514.1 - 0.18 12.1 0.0 0.29 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) Glycos_transf_2 PF00535.21 EPY53515.1 - 1.2e-26 93.4 0.0 1.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPY53515.1 - 2.8e-08 33.8 0.0 3.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EPY53515.1 - 0.049 12.7 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Abhydrolase_1 PF00561.15 EPY53516.1 - 1.9e-37 129.0 0.0 5.2e-37 127.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPY53516.1 - 2.1e-13 50.6 0.7 1.4e-12 48.0 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY53516.1 - 0.0018 18.0 0.3 0.94 9.2 0.1 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EPY53516.1 - 0.028 14.2 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein IlvN PF07991.7 EPY53517.1 - 8.7e-48 161.7 0.1 1.3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EPY53517.1 - 1.1e-46 158.3 0.0 1.9e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EPY53517.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPY53517.1 - 0.042 14.2 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SpoU_methylase PF00588.14 EPY53518.1 - 3.3e-31 108.0 0.0 5.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EPY53518.1 - 2.4e-14 53.2 0.0 4.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Methyltrn_RNA_4 PF09936.4 EPY53518.1 - 9e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase Actin PF00022.14 EPY53519.1 - 2.8e-100 335.5 0.0 3.7e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Actin RLAN PF14401.1 EPY53519.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain Peptidase_M10_C PF08548.6 EPY53520.1 - 0.033 13.7 1.0 0.11 12.0 0.7 1.7 1 1 0 1 1 1 0 Peptidase M10 serralysin C terminal zf-primase PF09329.6 EPY53521.1 - 4.4e-15 54.9 2.2 9.5e-15 53.9 1.5 1.6 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EPY53521.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FliD_N PF02465.13 EPY53521.1 - 1.3 9.4 11.9 1 9.7 3.8 3.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF999 PF06198.6 EPY53523.1 - 0.016 14.9 1.8 0.073 12.8 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF999) Tetraspannin PF00335.15 EPY53524.1 - 0.18 11.0 8.2 0.24 10.6 5.7 1.1 1 0 0 1 1 1 0 Tetraspanin family MUG2_C PF08593.5 EPY53525.1 - 6.1e-07 29.5 0.3 1.3e-06 28.5 0.2 1.6 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal RNase_H2-Ydr279 PF09468.5 EPY53527.1 - 5.4e-47 160.4 0.0 6.3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Cortex-I_coil PF09304.5 EPY53527.1 - 0.029 14.4 1.1 0.71 9.9 0.2 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil RNase_T PF00929.19 EPY53528.1 - 4.4e-32 111.6 0.1 5.8e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.20 EPY53529.1 - 1.3e-33 116.2 0.0 1.7e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53529.1 - 8.3e-12 44.7 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY53529.1 - 0.0023 17.7 0.0 2.6 7.7 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family DnaJ PF00226.26 EPY53530.1 - 1.4e-27 95.2 0.8 2.3e-27 94.5 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPY53530.1 - 1.5e-15 56.9 10.1 2.6e-15 56.2 7.0 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EPY53530.1 - 3e-14 52.6 0.1 5.6e-13 48.5 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain FdhE PF04216.7 EPY53530.1 - 0.48 10.0 3.6 0.88 9.2 1.8 1.8 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Lar_restr_allev PF14354.1 EPY53530.1 - 4.3 7.7 11.7 11 6.4 0.8 3.9 2 1 2 4 4 4 0 Restriction alleviation protein Lar Tim54 PF11711.3 EPY53531.1 - 1.2e-63 215.0 0.1 1.7e-61 207.9 0.1 2.1 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pil1 PF13805.1 EPY53532.1 - 4.5e-46 157.1 0.2 4.5e-46 157.1 0.2 1.4 2 0 0 2 2 2 1 Eisosome component PIL1 Anticodon_1 PF08264.8 EPY53532.1 - 0.078 12.7 0.7 1.3 8.7 0.1 2.4 1 1 1 2 2 2 0 Anticodon-binding domain of tRNA FKBP_C PF00254.23 EPY53533.1 - 7.8e-29 99.5 0.3 3.6e-28 97.4 0.1 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nucleoplasmin PF03066.10 EPY53533.1 - 0.011 15.2 8.7 0.011 15.2 6.0 3.7 1 1 2 3 3 3 0 Nucleoplasmin LMBR1 PF04791.11 EPY53533.1 - 0.77 8.2 5.5 1.1 7.7 3.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIF_alpha PF05793.7 EPY53533.1 - 2.4 6.4 43.0 4.1 5.6 29.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 EPY53533.1 - 2.4 5.7 15.8 3 5.4 10.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 EPY53533.1 - 4.5 5.6 36.3 0.6 8.5 22.2 1.6 2 0 0 2 2 2 0 Daxx Family IMS PF00817.15 EPY53534.1 - 8.6e-42 142.4 0.2 2.3e-41 141.0 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EPY53534.1 - 2.4e-09 37.1 0.0 6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EPY53534.1 - 9.2e-08 32.1 0.1 3.5e-07 30.2 0.1 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 EPY53534.1 - 1.7e-07 31.1 12.0 0.0005 19.9 4.7 3.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4414) PTCB-BRCT PF12738.2 EPY53534.1 - 0.00014 21.6 0.0 0.00032 20.4 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.6 EPY53534.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) WD40 PF00400.27 EPY53535.1 - 2.7e-42 141.1 24.7 1.6e-09 37.2 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat IKI3 PF04762.7 EPY53535.1 - 0.51 8.0 6.1 1.4 6.6 1.2 2.0 2 0 0 2 2 2 0 IKI3 family Snf7 PF03357.16 EPY53536.1 - 8.7e-28 96.8 6.0 1e-27 96.5 4.2 1.1 1 0 0 1 1 1 1 Snf7 DUF826 PF05696.6 EPY53536.1 - 0.045 13.8 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF826) PIF1 PF05970.9 EPY53536.1 - 0.06 12.2 0.3 0.081 11.8 0.2 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF836 PF05768.9 EPY53536.1 - 0.1 12.8 0.7 0.26 11.5 0.5 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GTP_EFTU PF00009.22 EPY53538.1 - 3.2e-40 137.5 0.0 5.7e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPY53538.1 - 3.9e-27 94.1 0.0 7.5e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPY53538.1 - 6.9e-20 70.7 0.0 1.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPY53538.1 - 3.7e-10 39.7 0.0 8.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EPY53538.1 - 1.4e-06 28.7 0.0 4.2e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 EPY53538.1 - 3.6e-05 23.5 0.0 0.00016 21.4 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.5 EPY53538.1 - 0.0016 17.6 0.0 0.0079 15.4 0.0 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPY53538.1 - 0.028 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Ras family Thiolase_N PF00108.18 EPY53539.1 - 1.8e-97 325.4 2.7 1.8e-97 325.4 1.8 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPY53539.1 - 9.2e-42 141.3 0.6 1.5e-40 137.4 0.2 2.6 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPY53539.1 - 0.00059 19.3 1.4 0.00059 19.3 0.9 2.5 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPY53539.1 - 0.0026 17.3 0.6 0.13 11.9 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CPSase_L_D2 PF02786.12 EPY53540.1 - 2.7e-111 369.9 0.2 1.3e-84 282.7 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EPY53540.1 - 1e-40 138.2 0.1 2.1e-40 137.2 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EPY53540.1 - 6.4e-37 127.0 0.1 6e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EPY53540.1 - 4.1e-34 116.9 0.0 2.4e-16 59.8 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EPY53540.1 - 1.6e-22 79.6 0.0 1.8e-10 40.1 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EPY53540.1 - 1.3e-20 73.4 0.1 4.1e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPY53540.1 - 3.4e-17 62.4 0.5 2.6e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EPY53540.1 - 2.7e-11 43.3 0.0 8e-06 25.4 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EPY53540.1 - 1.6e-08 34.5 1.5 0.00069 19.5 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.14 EPY53540.1 - 6.8e-06 25.7 0.9 0.035 13.6 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EPY53540.1 - 2.9e-05 23.3 0.0 0.063 12.4 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain NAD_Gly3P_dh_N PF01210.18 EPY53541.1 - 3.4e-57 192.5 0.0 5.6e-56 188.6 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPY53541.1 - 1.6e-50 170.7 0.1 3.5e-50 169.5 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EPY53541.1 - 0.00012 22.4 0.1 0.00063 20.1 0.0 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 EPY53541.1 - 0.019 14.6 0.6 5.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Rossmann-like domain PWWP PF00855.12 EPY53542.1 - 7e-15 55.0 0.2 7e-15 55.0 0.1 3.2 2 0 0 2 2 2 1 PWWP domain zf-LYAR PF08790.6 EPY53543.1 - 4.3e-15 55.0 3.4 9.8e-15 53.9 2.4 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger LIM PF00412.17 EPY53543.1 - 0.61 10.2 7.2 0.52 10.4 3.5 1.9 1 1 0 1 1 1 0 LIM domain RPN7 PF10602.4 EPY53545.1 - 1.8e-46 157.7 1.7 1.8e-46 157.7 1.2 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EPY53545.1 - 1.6e-15 57.2 0.4 3.9e-14 52.8 0.0 2.7 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EPY53545.1 - 2.3e-05 23.9 1.7 0.024 14.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY53545.1 - 0.00018 20.9 1.8 0.052 13.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53545.1 - 0.00022 21.0 2.5 0.35 10.8 0.2 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPY53545.1 - 0.00028 21.2 0.1 0.033 14.8 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPY53545.1 - 0.00095 18.7 1.5 0.31 10.7 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 EPY53545.1 - 0.0025 17.4 2.5 0.99 9.3 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY53545.1 - 0.003 17.2 0.2 2.8 7.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPY53545.1 - 0.011 15.6 0.4 0.42 10.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EPY53545.1 - 0.055 12.9 2.0 0.57 9.6 0.3 2.5 2 1 0 2 2 2 0 Foie gras liver health family 1 TPR_16 PF13432.1 EPY53545.1 - 0.13 13.0 0.4 6.8 7.4 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Prefoldin PF02996.12 EPY53546.1 - 1.9e-24 85.6 1.8 4.7e-24 84.3 0.2 1.9 1 1 1 2 2 2 2 Prefoldin subunit Cep57_MT_bd PF06657.8 EPY53546.1 - 5.8e-06 26.1 1.2 0.038 13.9 0.1 2.3 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Prefoldin_2 PF01920.15 EPY53546.1 - 0.00015 21.4 1.5 0.054 13.2 0.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit COG5 PF10392.4 EPY53546.1 - 0.0078 16.1 3.0 0.77 9.7 0.1 2.3 2 0 0 2 2 2 2 Golgi transport complex subunit 5 ZapA PF05164.8 EPY53546.1 - 0.018 15.0 0.2 0.045 13.7 0.0 1.7 1 1 1 2 2 2 0 Cell division protein ZapA DUF1192 PF06698.6 EPY53546.1 - 0.026 14.3 1.6 0.19 11.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF812 PF05667.6 EPY53546.1 - 0.073 11.5 3.1 0.085 11.3 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Rad21_Rec8_N PF04825.8 EPY53546.1 - 0.094 12.6 1.2 0.38 10.7 0.3 2.0 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein V-SNARE PF05008.10 EPY53546.1 - 0.15 12.2 3.4 6.2 7.0 0.6 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus YlbD_coat PF14071.1 EPY53546.1 - 0.16 12.0 0.7 2.1 8.3 0.2 2.1 2 0 0 2 2 2 0 Putative coat protein Reo_sigmaC PF04582.7 EPY53546.1 - 0.19 10.9 2.4 2.4 7.2 0.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Not3 PF04065.10 EPY53546.1 - 0.25 10.5 2.9 0.21 10.8 0.5 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component BLOC1_2 PF10046.4 EPY53546.1 - 0.42 10.7 4.7 7.7 6.7 0.1 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FbpA PF05833.6 EPY53546.1 - 0.99 7.8 6.9 2.7 6.4 1.6 2.0 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) RabGAP-TBC PF00566.13 EPY53547.1 - 3.7e-49 167.0 1.1 8.2e-49 165.9 0.7 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EPY53547.1 - 6.3e-06 26.2 4.3 2.9e-05 24.1 0.3 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EPY53547.1 - 9.3e-06 25.1 1.2 0.11 12.4 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EPY53547.1 - 0.00013 21.0 1.9 0.39 10.1 0.0 3.8 3 0 0 3 3 3 2 EF hand GRAM PF02893.15 EPY53547.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 GRAM domain GrpE PF01025.14 EPY53548.1 - 5.7e-46 156.0 3.4 7e-46 155.7 2.3 1.1 1 0 0 1 1 1 1 GrpE Fez1 PF06818.10 EPY53548.1 - 0.0013 18.7 3.8 0.0018 18.3 2.6 1.3 1 0 0 1 1 1 1 Fez1 DUF812 PF05667.6 EPY53548.1 - 0.0089 14.5 5.6 0.011 14.2 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Pro_dh PF01619.13 EPY53548.1 - 0.014 14.4 2.0 0.02 13.9 1.4 1.2 1 0 0 1 1 1 0 Proline dehydrogenase V_ATPase_I PF01496.14 EPY53548.1 - 0.12 10.1 4.2 0.14 9.9 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EPY53548.1 - 0.2 10.5 8.6 0.27 10.1 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EPY53548.1 - 0.24 9.8 6.9 0.28 9.5 4.8 1.1 1 0 0 1 1 1 0 AAA domain Mit_KHE1 PF10173.4 EPY53548.1 - 0.26 11.1 3.4 0.47 10.2 2.4 1.4 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related OmpH PF03938.9 EPY53548.1 - 0.34 10.8 9.0 0.47 10.3 6.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EPY53548.1 - 0.56 9.7 6.3 0.83 9.2 4.3 1.3 1 0 0 1 1 1 0 IncA protein DUF4446 PF14584.1 EPY53548.1 - 0.72 9.6 7.7 6.3 6.6 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF2205 PF10224.4 EPY53548.1 - 2.7 7.6 12.4 0.23 11.0 2.0 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) ATP-synt_F PF01990.12 EPY53549.1 - 4.3e-29 100.7 0.2 4.9e-29 100.5 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Ins134_P3_kin PF05770.6 EPY53549.1 - 0.026 13.5 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase Fe-S_biosyn PF01521.15 EPY53550.1 - 1.8e-13 50.4 0.0 2.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Nup160 PF11715.3 EPY53551.1 - 1e-59 202.1 7.3 1.9e-59 201.2 5.1 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Sterol-sensing PF12349.3 EPY53552.1 - 2.6e-32 111.3 9.8 5.6e-32 110.3 6.8 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation BBS2_N PF14781.1 EPY53552.1 - 0.083 12.5 0.3 0.47 10.0 0.0 2.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal dsrm PF00035.20 EPY53553.1 - 5.8e-07 29.9 0.0 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EPY53553.1 - 0.00036 20.4 0.0 0.0014 18.5 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EPY53553.1 - 0.0014 19.0 0.0 0.0053 17.1 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain DND1_DSRM PF14709.1 EPY53553.1 - 0.026 14.7 0.0 0.074 13.3 0.0 1.8 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Sybindin PF04099.7 EPY53554.1 - 1.2e-49 167.7 0.1 1.3e-49 167.5 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EPY53554.1 - 3.1e-07 30.3 0.3 5.6e-07 29.4 0.2 1.4 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region ACOX PF01756.14 EPY53554.1 - 0.052 12.9 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA oxidase Ribosomal_60s PF00428.14 EPY53555.1 - 1.1e-24 86.5 11.7 1.4e-24 86.3 8.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein CSTF2_hinge PF14327.1 EPY53556.1 - 1.4e-20 73.1 3.1 1.4e-20 73.1 2.2 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EPY53556.1 - 9.5e-18 63.6 0.0 1.7e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53556.1 - 3.9e-09 36.3 0.0 9.6e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EPY53556.1 - 4.4e-07 29.0 5.0 1e-06 27.9 3.5 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 EPY53556.1 - 0.00032 20.4 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V-SNARE_C PF12352.3 EPY53557.1 - 2.1e-17 62.9 4.0 3.6e-17 62.1 2.0 2.0 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EPY53557.1 - 9e-14 51.3 0.0 2.4e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus YqjK PF13997.1 EPY53557.1 - 0.023 14.8 2.6 0.028 14.5 0.1 2.4 3 0 0 3 3 3 0 YqjK-like protein DUF106 PF01956.11 EPY53557.1 - 0.11 11.9 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF106 Prominin PF05478.6 EPY53557.1 - 0.12 9.8 0.0 0.23 8.9 0.0 1.5 1 1 0 1 1 1 0 Prominin OppC_N PF12911.2 EPY53557.1 - 0.31 10.4 2.4 0.59 9.5 1.7 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C GBP_C PF02841.9 EPY53557.1 - 0.32 10.1 1.9 0.43 9.7 0.1 1.8 1 1 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DASH_Dad4 PF08650.5 EPY53558.1 - 2.9e-32 110.4 7.5 3.1e-32 110.2 5.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EPY53558.1 - 0.0034 17.0 2.5 0.0043 16.7 1.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 SNARE PF05739.14 EPY53558.1 - 0.0058 16.2 1.1 0.0082 15.8 0.3 1.6 1 1 1 2 2 2 1 SNARE domain Pecanex_C PF05041.10 EPY53558.1 - 0.08 11.9 0.1 0.084 11.8 0.1 1.1 1 0 0 1 1 1 0 Pecanex protein (C-terminus) DUF1359 PF07097.6 EPY53558.1 - 0.099 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) Mer2 PF09074.5 EPY53558.1 - 0.12 12.3 0.8 0.12 12.2 0.6 1.1 1 0 0 1 1 1 0 Mer2 EAP30 PF04157.11 EPY53559.1 - 3.1e-40 137.7 1.2 4.9e-40 137.0 0.8 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EPY53559.1 - 3.1e-23 81.4 0.1 9.5e-23 79.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EPY53559.1 - 0.0002 20.4 4.2 0.00055 18.9 0.2 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.2 EPY53559.1 - 0.0017 18.1 14.4 0.0057 16.4 0.6 2.0 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 EPY53559.1 - 0.0048 16.0 0.7 0.0048 16.0 0.5 2.3 2 0 0 2 2 2 1 zinc-ribbon domain CagZ PF09053.5 EPY53559.1 - 0.11 11.8 1.1 0.18 11.1 0.1 1.8 2 0 0 2 2 2 0 CagZ GCC2_GCC3 PF07699.8 EPY53559.1 - 0.65 9.6 5.8 0.48 10.0 0.6 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 Mago_nashi PF02792.9 EPY53560.1 - 6.8e-83 275.4 1.0 7.6e-83 275.3 0.7 1.0 1 0 0 1 1 1 1 Mago nashi protein SHS2_Rpb7-N PF03876.12 EPY53561.1 - 4.2e-10 39.5 0.0 9.6e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPY53561.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain Autophagy_N PF03986.8 EPY53562.1 - 4.2e-35 120.6 0.1 5.7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EPY53562.1 - 2.7e-24 85.1 0.4 2.1e-23 82.2 0.1 2.4 3 0 0 3 3 3 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EPY53562.1 - 2.6e-12 45.5 3.9 5.9e-12 44.4 2.7 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-CHY PF05495.7 EPY53563.1 - 1.3e-15 57.2 11.7 1.7e-15 56.9 8.1 1.1 1 0 0 1 1 1 1 CHY zinc finger DUF2296 PF10058.4 EPY53563.1 - 0.014 15.1 2.6 0.032 13.9 1.8 1.7 1 1 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zinc_ribbon_2 PF13240.1 EPY53563.1 - 0.03 13.8 0.1 0.03 13.8 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EPY53563.1 - 0.047 13.5 0.4 0.047 13.5 0.3 1.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 EPY53563.1 - 0.056 13.2 6.5 0.22 11.3 4.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EPY53563.1 - 0.073 12.3 3.9 0.29 10.4 2.7 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EPY53563.1 - 0.11 12.0 8.4 1.1 8.9 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EPY53563.1 - 0.12 12.3 0.6 0.12 12.3 0.4 2.4 2 1 0 2 2 2 0 Zinc ribbon domain Trm112p PF03966.11 EPY53563.1 - 0.34 11.3 3.2 0.75 10.2 0.2 2.5 2 1 0 2 2 2 0 Trm112p-like protein zf-RING_3 PF14369.1 EPY53563.1 - 0.98 9.4 9.3 2 8.4 2.9 2.7 1 1 1 2 2 2 0 zinc-finger zinc_ribbon_4 PF13717.1 EPY53563.1 - 1.2 8.8 11.3 2.1 8.0 0.4 3.6 4 0 0 4 4 4 0 zinc-ribbon domain C1_4 PF07975.7 EPY53563.1 - 2.1 8.4 8.1 1.8 8.6 0.7 2.4 1 1 2 3 3 3 0 TFIIH C1-like domain zf-RING_4 PF14570.1 EPY53563.1 - 3.1 7.4 10.8 2.9 7.5 0.2 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.14 EPY53563.1 - 3.3 7.4 6.1 10 5.8 4.2 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 EPY53563.1 - 4.3 6.9 10.8 1.4 8.4 3.3 2.8 2 1 0 2 2 2 0 A2L zinc ribbon domain DCP1 PF06058.8 EPY53564.1 - 2.5e-35 121.2 0.5 2.8e-35 121.0 0.4 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family KH_dom-like PF14714.1 EPY53564.1 - 0.053 13.4 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal T2SE_Nter PF05157.10 EPY53564.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain WH1 PF00568.18 EPY53564.1 - 0.11 12.2 0.3 0.54 10.0 0.2 2.0 1 1 0 1 1 1 0 WH1 domain Methyltransf_23 PF13489.1 EPY53565.1 - 6.5e-19 68.2 0.0 8.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY53565.1 - 8.6e-11 42.1 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY53565.1 - 1.6e-09 38.3 0.0 2.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY53565.1 - 6.7e-09 36.1 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPY53565.1 - 8.7e-09 34.8 0.0 2.2e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPY53565.1 - 3.5e-08 33.1 0.0 4.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY53565.1 - 3.1e-07 30.6 0.0 6.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPY53565.1 - 6.2e-06 25.6 0.0 9.8e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EPY53565.1 - 0.0016 17.7 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 EPY53565.1 - 0.003 16.6 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EPY53565.1 - 0.0067 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) N2227 PF07942.7 EPY53565.1 - 0.021 13.7 0.1 0.039 12.9 0.0 1.5 2 0 0 2 2 2 0 N2227-like protein Rsm22 PF09243.5 EPY53565.1 - 0.024 13.6 0.0 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_26 PF13659.1 EPY53565.1 - 0.086 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SRP54 PF00448.17 EPY53566.1 - 2.5e-50 170.6 0.1 4.4e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EPY53566.1 - 2e-25 89.7 18.1 1.3e-13 51.0 7.3 2.2 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EPY53566.1 - 1.1e-08 34.9 0.6 3.7e-08 33.3 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EPY53566.1 - 2.3e-07 30.4 0.0 9.3e-07 28.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EPY53566.1 - 4.4e-05 23.6 0.1 0.00027 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPY53566.1 - 0.00011 21.7 0.8 0.00061 19.3 0.0 2.2 2 1 0 2 2 2 1 AAA-like domain ArgK PF03308.11 EPY53566.1 - 0.00056 18.7 0.0 0.0013 17.6 0.0 1.6 1 0 0 1 1 1 1 ArgK protein ArsA_ATPase PF02374.10 EPY53566.1 - 0.00078 18.5 0.1 1.2 8.1 0.0 2.8 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_16 PF13191.1 EPY53566.1 - 0.0023 17.9 0.8 0.019 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EPY53566.1 - 0.01 15.7 1.3 0.036 14.0 0.3 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EPY53566.1 - 0.011 15.5 0.0 0.033 13.8 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EPY53566.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPY53566.1 - 0.018 14.9 0.7 0.13 12.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EPY53566.1 - 0.032 14.0 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EPY53566.1 - 0.036 14.2 0.4 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Fer4_NifH PF00142.13 EPY53566.1 - 0.044 12.9 0.0 0.092 11.9 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.1 EPY53566.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPY53566.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter DUF1049 PF06305.6 EPY53567.1 - 0.062 12.7 0.2 0.062 12.7 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1049) HSP20 PF00011.16 EPY53568.1 - 4.8e-22 77.7 0.5 5.9e-22 77.4 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY53568.1 - 0.021 15.3 0.3 0.05 14.1 0.1 1.7 2 0 0 2 2 2 0 CS domain DUF4097 PF13349.1 EPY53568.1 - 0.029 13.9 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Tic20 PF09685.5 EPY53569.1 - 0.17 11.8 16.3 0.043 13.7 7.4 2.0 1 1 1 2 2 2 0 Tic20-like protein DUF1129 PF06570.6 EPY53569.1 - 0.22 10.8 1.1 0.32 10.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2207 PF09972.4 EPY53569.1 - 1.7 7.1 6.1 2.6 6.5 4.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 EPY53569.1 - 2.9 7.2 10.0 0.97 8.8 5.0 1.7 2 1 0 2 2 2 0 Fatty acid desaturase DUF485 PF04341.7 EPY53569.1 - 7.6 6.3 9.3 3.4 7.4 4.5 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF485 EmrE PF13536.1 EPY53571.1 - 5.9 7.1 18.9 13 6.0 12.8 1.9 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Fes1 PF08609.5 EPY53572.1 - 3.8e-27 94.5 3.7 4.9e-23 81.4 0.1 2.3 2 0 0 2 2 2 2 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EPY53572.1 - 0.12 12.6 0.2 1.1 9.5 0.0 2.4 1 1 3 4 4 4 0 HEAT repeats G-patch_2 PF12656.2 EPY53573.1 - 1.5e-21 76.0 0.1 6.6e-21 73.9 0.0 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site MCM_bind PF09739.4 EPY53573.1 - 0.043 13.3 1.4 0.07 12.6 0.1 1.9 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor RVT_connect PF06815.8 EPY53574.1 - 0.077 12.8 1.1 0.089 12.6 0.8 1.1 1 0 0 1 1 1 0 Reverse transcriptase connection domain Pkinase PF00069.20 EPY53575.1 - 4.3e-68 229.2 0.0 5.4e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53575.1 - 1.3e-34 119.4 0.0 1.8e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY53575.1 - 7.2e-07 28.4 0.1 3.9e-06 26.0 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EPY53575.1 - 0.0013 18.5 0.1 0.032 13.9 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EPY53575.1 - 0.0099 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPY53575.1 - 0.074 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EPY53575.1 - 0.075 12.5 0.2 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EPY53575.1 - 0.089 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EPY53575.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HMG_box PF00505.14 EPY53576.1 - 8.9e-14 51.5 0.3 1.6e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EPY53576.1 - 0.0046 16.3 0.1 0.0093 15.3 0.1 1.5 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 4HBT PF03061.17 EPY53577.1 - 1.6e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Cyto_heme_lyase PF01265.12 EPY53578.1 - 3e-65 220.3 9.2 3e-65 220.3 6.4 2.3 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase RNB PF00773.14 EPY53579.1 - 2.7e-93 312.8 0.1 3.6e-93 312.4 0.1 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EPY53579.1 - 6.9e-10 39.1 0.0 2.2e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 PIN domain CRC_subunit PF08624.5 EPY53580.1 - 7.8e-42 142.4 0.0 1.2e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit GN3L_Grn1 PF08701.6 EPY53581.1 - 1.5e-24 85.6 10.6 1.5e-24 85.6 7.3 2.2 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EPY53581.1 - 7.8e-19 67.7 0.1 5.5e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPY53581.1 - 2e-06 27.3 0.0 0.0016 17.9 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPY53581.1 - 5.5e-06 26.3 4.7 0.014 15.1 0.1 3.3 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 EPY53581.1 - 0.00017 20.8 0.0 0.0006 19.1 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EPY53581.1 - 0.00023 20.3 0.1 0.00039 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MCM PF00493.18 EPY53581.1 - 0.0023 16.8 0.3 0.073 11.8 0.2 2.2 2 0 0 2 2 2 1 MCM2/3/5 family Miro PF08477.8 EPY53581.1 - 0.0027 18.1 0.2 0.11 13.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EPY53581.1 - 0.013 14.6 0.0 0.052 12.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family MobB PF03205.9 EPY53581.1 - 0.055 13.1 0.3 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Torsin PF06309.6 EPY53581.1 - 0.067 13.0 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.1 EPY53581.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EPY53581.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.8 3 1 0 3 3 3 0 AAA domain Tubulin PF00091.20 EPY53582.1 - 2.8e-71 239.7 0.0 4.6e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPY53582.1 - 2.8e-46 156.6 0.1 5.1e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPY53582.1 - 3.5e-05 23.8 0.0 8.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EPY53582.1 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF1674 PF07896.7 EPY53583.1 - 2.9e-14 52.9 1.0 4.8e-14 52.3 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) DUF999 PF06198.6 EPY53584.1 - 0.0018 18.0 1.1 0.0073 16.0 0.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF999) Tetraspannin PF00335.15 EPY53585.1 - 0.15 11.3 7.8 0.2 10.9 5.4 1.1 1 0 0 1 1 1 0 Tetraspanin family Tetraspannin PF00335.15 EPY53586.1 - 0.47 9.6 9.2 0.58 9.3 6.4 1.1 1 0 0 1 1 1 0 Tetraspanin family COX17 PF05051.8 EPY53587.1 - 4.7e-22 77.7 5.9 5.7e-22 77.4 4.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DUF3235 PF11574.3 EPY53587.1 - 0.0042 17.2 0.0 0.0057 16.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3235) PAAR_motif PF05488.8 EPY53587.1 - 0.19 11.7 1.1 0.29 11.1 0.8 1.5 1 1 0 1 1 1 0 PAAR motif Nt_Gln_amidase PF09764.4 EPY53588.1 - 3.7e-54 182.8 0.9 4.2e-54 182.6 0.6 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Thioredoxin PF00085.15 EPY53589.1 - 2e-18 66.0 0.1 3e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 EPY53589.1 - 9.5e-18 63.9 0.0 5.7e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_2 PF13098.1 EPY53589.1 - 0.0001 22.4 0.0 0.0025 17.9 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPY53589.1 - 0.00019 21.4 0.0 0.038 14.0 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EPY53589.1 - 0.0028 17.6 0.1 0.0057 16.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EPY53589.1 - 0.0049 16.3 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF2847 PF11009.3 EPY53589.1 - 0.041 13.4 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) GST_N_3 PF13417.1 EPY53589.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Metallophos PF00149.23 EPY53590.1 - 1.2e-40 139.0 0.2 1.5e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3608 PF12257.3 EPY53591.1 - 3.2e-80 269.0 0.9 6.3e-79 264.7 0.6 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EPY53591.1 - 1.3e-21 76.1 0.0 3.5e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PEMT PF04191.8 EPY53592.1 - 7.9e-57 189.9 13.9 1.2e-34 118.5 0.5 3.4 3 0 0 3 3 3 2 Phospholipid methyltransferase V-SNARE_C PF12352.3 EPY53593.1 - 2.1e-05 24.4 1.2 0.0066 16.4 0.3 2.8 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.14 EPY53593.1 - 0.00013 21.5 0.1 0.00013 21.5 0.1 3.5 3 0 0 3 3 3 1 SNARE domain Thi4 PF01946.12 EPY53594.1 - 2.8e-105 350.4 0.1 4.9e-105 349.7 0.0 1.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EPY53594.1 - 2.9e-09 36.2 0.9 8.1e-07 28.2 0.8 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPY53594.1 - 5.9e-06 26.2 0.4 1.9e-05 24.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPY53594.1 - 6.4e-06 25.3 0.4 7.3e-05 21.8 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPY53594.1 - 1.3e-05 25.1 0.1 2.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPY53594.1 - 1.9e-05 23.7 2.1 0.0016 17.3 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EPY53594.1 - 9.5e-05 21.6 0.2 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPY53594.1 - 0.00025 21.1 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPY53594.1 - 0.0017 18.1 1.7 0.0035 17.1 0.1 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPY53594.1 - 0.0036 15.9 0.4 0.0089 14.7 0.3 1.6 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EPY53594.1 - 0.022 13.2 0.6 0.038 12.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EPY53594.1 - 0.06 12.2 0.1 0.37 9.6 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF1896 PF08989.5 EPY53594.1 - 0.14 11.9 0.1 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) PALP PF00291.20 EPY53595.1 - 6.8e-74 248.8 0.2 8.4e-74 248.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EPY53595.1 - 1.3e-37 127.2 0.0 1e-19 69.8 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DPM3 PF08285.6 EPY53596.1 - 2.5e-23 81.7 0.2 2.8e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SH3_9 PF14604.1 EPY53597.1 - 5.4e-14 51.4 0.0 9.5e-14 50.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPY53597.1 - 8.5e-14 50.7 0.1 1.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPY53597.1 - 3.3e-13 48.8 0.0 5e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain FGE-sulfatase PF03781.11 EPY53599.1 - 2.7e-27 95.7 0.5 8.2e-26 90.9 0.0 2.6 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Methyltransf_33 PF10017.4 EPY53599.1 - 1.7e-26 92.5 0.6 2.9e-26 91.8 0.4 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.1 EPY53599.1 - 4e-05 23.9 0.0 8.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.2 EPY53599.1 - 0.0014 18.9 0.3 0.0044 17.3 0.2 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_32 PF13679.1 EPY53599.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Apc3 PF12895.2 EPY53600.1 - 0.0031 17.5 1.4 7.3 6.8 0.2 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF4243 PF14027.1 EPY53601.1 - 1.4e-05 24.7 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Mito_carr PF00153.22 EPY53602.1 - 7.8e-52 172.9 4.1 2.5e-16 59.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2805 PF10985.3 EPY53602.1 - 0.03 14.2 0.1 0.2 11.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2805) PGI PF00342.14 EPY53603.1 - 6.8e-217 720.6 0.0 7.7e-217 720.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CBF PF03914.12 EPY53604.1 - 3.7e-39 133.7 0.4 8.7e-39 132.5 0.3 1.7 1 0 0 1 1 1 1 CBF/Mak21 family YcbB PF08664.5 EPY53604.1 - 0.24 11.1 1.1 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 YcbB domain Mt_ATP-synt_B PF05405.9 EPY53605.1 - 5.3e-46 156.0 4.0 7.2e-46 155.6 2.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF212 PF02681.9 EPY53605.1 - 0.16 11.7 2.3 0.19 11.4 0.3 2.0 2 0 0 2 2 2 0 Divergent PAP2 family DivIC PF04977.10 EPY53605.1 - 0.65 9.5 5.3 0.2 11.1 0.8 2.2 3 0 0 3 3 3 0 Septum formation initiator Arm PF00514.18 EPY53606.1 - 5.3e-90 292.5 11.6 2.9e-12 45.9 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPY53606.1 - 2e-23 82.4 0.0 3.5e-07 30.4 0.0 5.6 1 1 5 6 6 6 5 HEAT repeats IBB PF01749.15 EPY53606.1 - 2.2e-20 72.5 9.4 4.2e-20 71.7 6.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EPY53606.1 - 4.6e-20 71.4 0.5 2.6e-07 30.9 0.0 6.3 5 2 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 EPY53606.1 - 1.2e-18 65.4 0.6 0.00012 21.8 0.0 8.1 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 EPY53606.1 - 1e-06 27.3 0.0 0.00041 18.8 0.0 3.3 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EPY53606.1 - 0.00038 20.3 0.0 7.6 6.4 0.0 4.2 2 2 3 5 5 5 2 V-ATPase subunit H Proteasom_PSMB PF10508.4 EPY53606.1 - 0.0011 17.3 1.6 0.018 13.3 0.1 3.1 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 EPY53606.1 - 0.017 14.1 0.8 0.031 13.3 0.0 1.9 2 0 0 2 2 2 0 Mo25-like HEAT_PBS PF03130.11 EPY53606.1 - 0.12 12.8 0.1 17 6.2 0.0 3.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RNase_T PF00929.19 EPY53607.1 - 9e-29 100.8 0.0 1.7e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EPY53607.1 - 1.5e-05 24.5 0.1 7.2e-05 22.3 0.1 2.1 1 1 0 1 1 1 1 3'-5' exonuclease BRICHOS PF04089.9 EPY53607.1 - 0.097 12.5 0.3 1.3 8.9 0.0 2.6 2 1 0 2 2 2 0 BRICHOS domain LIM_bind PF01803.11 EPY53607.1 - 0.15 11.1 0.5 0.26 10.3 0.4 1.4 1 0 0 1 1 1 0 LIM-domain binding protein Med21 PF11221.3 EPY53608.1 - 3.7e-30 104.7 4.1 4.2e-30 104.6 2.8 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EPY53608.1 - 5.9e-06 25.9 2.6 8.2e-06 25.4 1.2 1.7 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Beach PF02138.13 EPY53608.1 - 4e-05 23.1 1.0 4.5e-05 23.0 0.7 1.0 1 0 0 1 1 1 1 Beige/BEACH domain TMF_DNA_bd PF12329.3 EPY53608.1 - 0.0037 17.0 4.8 0.0061 16.3 3.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.8 EPY53608.1 - 0.0038 16.2 5.2 0.0049 15.8 3.6 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Sipho_Gp157 PF05565.6 EPY53608.1 - 0.0061 16.1 2.3 0.0061 16.1 1.6 1.7 2 0 0 2 2 2 1 Siphovirus Gp157 MAD PF05557.8 EPY53608.1 - 0.01 13.9 3.8 0.013 13.6 2.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4404 PF14357.1 EPY53608.1 - 0.016 15.5 1.2 0.016 15.5 0.8 1.9 2 1 1 3 3 2 0 Domain of unknown function (DUF4404) EzrA PF06160.7 EPY53608.1 - 0.021 12.9 2.5 0.029 12.5 1.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 EPY53608.1 - 0.046 13.8 2.9 0.064 13.3 0.8 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF607 PF04678.8 EPY53608.1 - 0.054 13.4 0.3 0.068 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 TruB_N PF01509.13 EPY53608.1 - 0.083 13.0 0.9 0.11 12.6 0.6 1.3 1 1 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) DUF4618 PF15397.1 EPY53608.1 - 0.14 11.4 5.8 1.2 8.4 4.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF904 PF06005.7 EPY53608.1 - 0.3 11.4 4.8 0.81 10.0 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Mnd1 PF03962.10 EPY53608.1 - 0.53 9.9 6.9 0.32 10.6 3.5 1.6 1 1 0 1 1 1 0 Mnd1 family XhlA PF10779.4 EPY53608.1 - 0.65 9.9 3.1 1.5 8.7 2.1 1.5 1 0 0 1 1 1 0 Haemolysin XhlA F1F0-ATPsyn_F PF10791.4 EPY53609.1 - 1.4e-34 118.1 0.5 1.5e-34 118.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EPY53609.1 - 0.056 13.4 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f APG6 PF04111.7 EPY53610.1 - 7 5.5 10.9 34 3.3 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Spindle_Spc25 PF08234.7 EPY53611.1 - 3.2e-26 91.1 0.8 3.2e-26 91.1 0.6 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Metal_resist PF13801.1 EPY53611.1 - 0.022 14.7 4.8 0.045 13.7 3.3 1.5 1 1 0 1 1 1 0 Heavy-metal resistance APG6 PF04111.7 EPY53611.1 - 0.23 10.4 19.9 0.063 12.3 9.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 EPY53611.1 - 0.38 9.7 8.7 0.61 9.0 6.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF4441 PF14536.1 EPY53611.1 - 0.64 10.0 11.8 0.5 10.3 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) Occludin_ELL PF07303.8 EPY53611.1 - 6.4 7.5 15.9 14 6.4 7.5 3.1 2 1 1 3 3 3 0 Occludin homology domain Ribosomal_L32p PF01783.18 EPY53612.1 - 1.1e-15 57.5 4.7 1.4e-15 57.2 3.2 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Rad50_zn_hook PF04423.9 EPY53612.1 - 0.0076 15.6 0.6 0.36 10.3 0.0 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif DZR PF12773.2 EPY53612.1 - 0.017 14.9 0.7 0.027 14.2 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.7 EPY53612.1 - 0.04 13.6 1.5 2.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.1 EPY53612.1 - 0.052 12.7 3.0 0.084 12.1 2.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PolC_DP2 PF03833.8 EPY53612.1 - 0.1 10.2 0.2 0.11 10.1 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 RecR PF02132.10 EPY53612.1 - 0.12 11.8 0.4 0.18 11.2 0.3 1.3 1 0 0 1 1 1 0 RecR protein Zn-ribbon_8 PF09723.5 EPY53612.1 - 0.18 11.7 2.6 3.3 7.7 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain DUF1610 PF07754.6 EPY53612.1 - 1 9.5 4.9 10 6.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) DNA_ligase_ZBD PF03119.11 EPY53612.1 - 2.1 8.0 6.5 1.9 8.2 1.0 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Pkinase PF00069.20 EPY53613.1 - 5e-73 245.4 0.0 7.7e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53613.1 - 2.3e-48 164.5 0.0 3.8e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EPY53613.1 - 6.4e-22 77.7 2.7 7.4e-22 77.5 0.0 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EPY53613.1 - 1.4e-08 34.0 0.1 2.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EPY53613.1 - 0.00052 19.2 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain MafB19-deam PF14437.1 EPY53613.1 - 0.0088 15.6 1.3 0.02 14.5 0.6 1.7 2 0 0 2 2 2 1 MafB19-like deaminase APH PF01636.18 EPY53613.1 - 0.025 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPY53613.1 - 0.027 13.5 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPY53613.1 - 0.028 13.7 1.7 0.066 12.5 0.0 2.3 3 0 0 3 3 3 0 RIO1 family Gpi16 PF04113.9 EPY53614.1 - 1.4e-158 528.4 1.0 5.1e-157 523.3 0.7 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component G-patch PF01585.18 EPY53615.1 - 1e-08 34.8 0.1 1.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 G-patch domain AdoMet_MTase PF07757.8 EPY53615.1 - 0.044 13.8 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DUF2454 PF10521.4 EPY53616.1 - 8.7e-29 100.4 4.1 1.9e-28 99.2 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) RSS_P20 PF11757.3 EPY53616.1 - 0.013 15.6 1.1 0.037 14.1 0.1 2.2 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like Snf7 PF03357.16 EPY53617.1 - 6.2e-16 58.2 6.2 1.4e-15 57.1 4.4 1.4 2 0 0 2 2 2 1 Snf7 P16-Arc PF04699.9 EPY53617.1 - 0.33 10.9 4.4 4 7.4 0.2 2.3 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) FliD_C PF07195.7 EPY53617.1 - 0.34 10.1 4.9 3.8 6.7 0.4 3.1 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Kinesin PF00225.18 EPY53618.1 - 1.4e-98 329.7 3.4 1.4e-98 329.7 2.4 2.1 2 0 0 2 2 2 1 Kinesin motor domain SbcD_C PF12320.3 EPY53618.1 - 0.0023 17.9 3.5 0.0081 16.1 2.4 2.0 1 0 0 1 1 1 1 Type 5 capsule protein repressor C-terminal domain WXG100 PF06013.7 EPY53618.1 - 0.021 14.8 1.0 0.057 13.4 0.7 1.8 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF4043 PF13252.1 EPY53618.1 - 0.024 13.6 0.0 0.058 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) PEP-utilisers_N PF05524.8 EPY53618.1 - 0.19 11.5 2.5 0.49 10.2 1.7 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Sec8_exocyst PF04048.9 EPY53618.1 - 0.52 9.9 9.0 0.7 9.5 0.4 3.3 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain IncA PF04156.9 EPY53618.1 - 3.2 7.2 21.4 3.1 7.3 11.9 2.7 1 1 2 3 3 3 0 IncA protein ThiF PF00899.16 EPY53621.1 - 5.4e-49 165.5 0.0 6.6e-32 110.1 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EPY53621.1 - 2.4e-42 144.0 0.0 5.4e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EPY53621.1 - 4.1e-33 112.7 0.6 2.2e-23 81.6 0.0 2.8 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPY53621.1 - 8.2e-27 92.3 0.6 2.5e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EPY53621.1 - 0.024 14.7 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RNase_PH PF01138.16 EPY53622.1 - 3.1e-30 105.1 0.0 4.2e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 UQ_con PF00179.21 EPY53623.1 - 3.7e-35 120.3 0.1 4.8e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spc97_Spc98 PF04130.8 EPY53624.1 - 2.2e-22 79.0 15.8 4.8e-15 54.8 2.9 2.1 2 0 0 2 2 2 2 Spc97 / Spc98 family SF3b10 PF07189.6 EPY53625.1 - 3e-36 123.0 0.0 3.4e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MCM PF00493.18 EPY53626.1 - 5.2e-139 462.6 0.6 8.7e-139 461.9 0.4 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPY53626.1 - 5.5e-23 81.7 0.1 5.5e-23 81.7 0.1 2.2 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPY53626.1 - 4.8e-08 32.4 0.0 4.8e-07 29.1 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPY53626.1 - 0.00083 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EPY53626.1 - 0.0019 17.9 0.1 0.012 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPY53626.1 - 0.002 17.7 0.0 0.006 16.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Tir_receptor_M PF03549.9 EPY53626.1 - 0.015 15.4 0.0 0.052 13.6 0.0 1.9 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Sec7 PF01369.15 EPY53627.1 - 1.2e-65 220.8 1.2 3.4e-65 219.2 0.2 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EPY53627.1 - 1.5e-19 70.0 5.6 5.7e-11 42.1 2.2 3.6 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Suf PF05843.9 EPY53628.1 - 1.1e-21 77.8 13.6 0.00011 22.0 0.0 6.2 4 2 1 5 5 5 4 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EPY53628.1 - 1.6e-12 46.8 0.8 14 6.6 0.0 10.5 8 1 3 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53628.1 - 1.1e-10 41.3 0.6 0.0031 17.3 0.0 6.3 3 1 3 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EPY53628.1 - 1.8e-09 36.9 4.7 0.036 12.9 0.0 6.4 2 2 3 5 5 5 4 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 EPY53628.1 - 3.4e-09 37.1 1.2 0.11 13.2 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY53628.1 - 7e-07 29.5 0.1 1.2 9.5 0.0 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EPY53628.1 - 6.3e-05 22.7 3.2 8.9 6.1 0.0 5.8 5 0 0 5 5 5 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 EPY53628.1 - 0.00044 19.8 1.8 1.7 8.6 0.1 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat RPN7 PF10602.4 EPY53628.1 - 0.00081 18.8 0.6 0.0048 16.2 0.0 2.5 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 EPY53628.1 - 0.003 17.2 6.9 0.82 9.5 0.2 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY53628.1 - 0.0051 16.6 13.7 0.68 9.9 0.2 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 EPY53628.1 - 0.073 13.2 3.6 56 3.9 0.0 5.2 5 1 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EPY53628.1 - 0.17 11.9 3.2 8.8 6.5 0.1 4.3 5 0 0 5 5 3 0 PPR repeat TPR_17 PF13431.1 EPY53628.1 - 1.7 9.0 6.0 58 4.2 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.17 EPY53629.1 - 2.1e-22 78.7 0.0 3e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e IF-2B PF01008.12 EPY53630.1 - 1.6e-71 240.6 0.4 1.8e-71 240.3 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Prominin PF05478.6 EPY53630.1 - 0.018 12.6 0.0 0.024 12.2 0.0 1.1 1 0 0 1 1 1 0 Prominin TPR_1 PF00515.23 EPY53631.1 - 8.2e-48 158.1 41.1 1.7e-08 33.7 0.1 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EPY53631.1 - 6.2e-44 147.4 31.3 1.6e-11 43.6 0.6 6.6 2 2 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 EPY53631.1 - 1e-41 137.4 36.9 5.2e-06 25.9 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53631.1 - 3e-29 100.7 32.9 1.4e-07 31.2 0.1 7.4 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 EPY53631.1 - 6.9e-28 94.3 29.5 8.5e-05 22.0 0.1 10.3 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EPY53631.1 - 2.3e-27 94.9 19.2 7.2e-08 32.9 0.1 7.0 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EPY53631.1 - 6.4e-27 91.4 22.6 0.0041 17.1 0.0 10.6 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.1 EPY53631.1 - 3.2e-26 89.4 16.5 0.0033 17.9 0.0 9.6 2 2 8 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.1 EPY53631.1 - 2.1e-18 66.3 21.3 0.00089 19.5 0.3 6.9 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPY53631.1 - 5e-18 64.2 28.5 0.004 17.5 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_7 PF13176.1 EPY53631.1 - 6.4e-14 50.5 29.0 0.013 15.2 0.1 9.9 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPY53631.1 - 1.8e-10 40.5 19.0 0.0068 16.2 0.1 6.7 2 2 4 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 EPY53631.1 - 2.2e-10 40.5 20.6 5.6e-07 29.6 2.6 4.4 2 2 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EPY53631.1 - 1.6e-05 24.8 0.3 0.98 9.5 0.0 4.8 2 2 2 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 EPY53631.1 - 0.0039 16.0 0.8 1.5 7.4 0.0 2.6 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 EPY53631.1 - 9.3 5.2 18.9 18 4.3 1.3 4.7 3 3 1 4 4 4 0 Soluble NSF attachment protein, SNAP Rgp1 PF08737.5 EPY53632.1 - 3.4e-57 194.4 0.1 7.1e-57 193.3 0.0 1.5 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EPY53632.1 - 0.0013 18.5 0.0 0.015 15.1 0.0 2.7 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Transglut_C PF00927.17 EPY53632.1 - 0.068 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain RFC1 PF08519.7 EPY53633.1 - 1.4e-54 184.0 0.1 3.9e-54 182.6 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EPY53633.1 - 1.8e-13 50.4 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EPY53633.1 - 6.2e-12 45.8 0.0 1.5e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EPY53633.1 - 1.3e-05 24.1 0.1 8.7e-05 21.3 0.0 1.9 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPY53633.1 - 4.6e-05 23.5 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EPY53633.1 - 0.00052 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EPY53633.1 - 0.00063 19.4 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPY53633.1 - 0.0011 19.8 0.0 0.0029 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPY53633.1 - 0.0021 17.1 0.0 0.0042 16.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPY53633.1 - 0.0025 17.6 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SAGA-Tad1 PF12767.2 EPY53633.1 - 0.0053 16.4 0.0 0.0053 16.4 0.0 2.9 2 1 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit AAA_16 PF13191.1 EPY53633.1 - 0.0094 15.9 0.1 0.065 13.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EPY53633.1 - 0.018 14.9 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPY53633.1 - 0.019 14.7 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 EPY53633.1 - 0.028 14.7 0.0 0.08 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPY53633.1 - 0.091 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DHBP_synthase PF00926.14 EPY53634.1 - 8e-80 266.6 0.0 8.9e-80 266.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Peptidase_M24 PF00557.19 EPY53635.1 - 7.8e-14 51.7 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 BP28CT PF08146.7 EPY53636.1 - 1.2e-37 128.9 7.5 4.8e-37 127.0 4.6 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EPY53636.1 - 8.4e-14 51.5 2.5 1.8e-11 44.0 0.0 5.0 4 1 1 5 5 5 1 U3 small nucleolar RNA-associated protein 10 CN_hydrolase PF00795.17 EPY53637.1 - 2.4e-14 53.1 0.0 3.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SNF2_N PF00176.18 EPY53638.1 - 1.6e-71 240.5 0.2 2.6e-71 239.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY53638.1 - 2.8e-12 46.3 0.0 7.2e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EPY53638.1 - 5e-07 29.6 7.0 1.1e-06 28.5 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY53638.1 - 3.7e-06 26.4 4.4 1.9e-05 24.2 3.3 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY53638.1 - 2.4e-05 23.8 4.7 5.3e-05 22.8 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY53638.1 - 0.00019 21.1 6.5 0.00019 21.1 4.5 2.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EPY53638.1 - 0.0002 20.9 1.4 0.0002 20.9 0.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EPY53638.1 - 0.00075 19.1 5.9 0.0018 17.9 4.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EPY53638.1 - 0.0013 18.2 0.0 0.0032 16.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 EPY53638.1 - 0.0095 15.7 5.7 0.026 14.3 3.7 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EPY53638.1 - 0.02 14.6 1.9 0.047 13.4 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 EPY53638.1 - 0.093 12.4 2.3 0.21 11.3 1.6 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RRM_1 PF00076.17 EPY53639.1 - 5.3e-49 163.7 0.0 2.4e-18 65.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53639.1 - 3.5e-29 100.5 0.0 5e-09 36.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53639.1 - 2.8e-25 87.9 0.0 1.1e-12 47.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPY53639.1 - 4.8e-06 26.3 0.0 4.3e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif Cas_Cas2CT1978 PF09707.5 EPY53639.1 - 0.073 13.0 0.0 19 5.2 0.0 3.0 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.1 EPY53639.1 - 0.12 12.1 0.0 0.99 9.2 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Membr_traf_MHD PF10540.4 EPY53640.1 - 0.0023 17.7 0.1 0.014 15.1 0.1 2.4 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain SBDS PF01172.13 EPY53641.1 - 1.4e-16 60.0 0.2 1.4e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Pkinase PF00069.20 EPY53642.1 - 3.7e-39 134.4 0.0 2.6e-20 72.6 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53642.1 - 7.7e-14 51.3 0.0 2.2e-10 40.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EPY53642.1 - 0.00015 21.5 0.1 0.00068 19.4 0.0 2.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EPY53642.1 - 0.0017 17.3 0.1 0.0048 15.9 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase DUF4448 PF14610.1 EPY53643.1 - 3e-17 62.7 0.2 3.7e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EPY53643.1 - 0.0053 17.1 0.9 0.053 14.0 0.6 2.1 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4131 PF13567.1 EPY53643.1 - 0.041 13.2 0.5 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Spt4 PF06093.8 EPY53644.1 - 5.8e-23 80.5 0.0 7.3e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Aldedh PF00171.17 EPY53645.1 - 3e-126 421.4 0.0 3.4e-126 421.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Imm3 PF14425.1 EPY53645.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 SSPI PF14098.1 EPY53645.1 - 0.17 11.7 0.3 6.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Small, acid-soluble spore protein I TraG-D_C PF12696.2 EPY53646.1 - 0.15 11.9 1.8 50 3.7 0.0 4.1 4 0 0 4 4 4 0 TraM recognition site of TraD and TraG Ribosomal_S19e PF01090.14 EPY53647.1 - 4.8e-60 201.0 0.1 5.4e-60 200.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF953 PF06110.6 EPY53648.1 - 2.4e-14 52.7 0.0 2.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) DUF3521 PF12035.3 EPY53648.1 - 0.028 14.2 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) TUG-UBL1 PF11470.3 EPY53649.1 - 2.5e-17 62.5 0.1 9.5e-17 60.6 0.0 2.1 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EPY53649.1 - 0.00014 21.8 0.0 0.00057 19.9 0.0 2.0 1 1 1 2 2 2 1 UBX domain SOG2 PF10428.4 EPY53649.1 - 8.1 4.9 12.7 12 4.4 8.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RibD_C PF01872.12 EPY53650.1 - 8.1e-25 87.6 0.0 1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain FAA_hydrolase PF01557.13 EPY53651.1 - 2.5e-48 164.4 0.0 3e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aminotran_3 PF00202.16 EPY53652.1 - 1.6e-102 342.8 0.0 1.9e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 EPY53652.1 - 0.15 11.0 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_12 PF08242.7 EPY53653.1 - 2.9e-14 53.3 0.0 1.5e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY53653.1 - 8.1e-14 51.6 0.0 1.6e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPY53653.1 - 5e-11 42.9 0.0 2.1e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY53653.1 - 7.7e-09 35.8 0.0 2.4e-08 34.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY53653.1 - 1e-07 32.4 0.0 1.8e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY53653.1 - 3.2e-07 30.0 0.0 1.1e-06 28.2 0.0 2.0 3 1 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EPY53653.1 - 9.9e-07 27.9 0.0 0.0093 14.9 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EPY53653.1 - 6.8e-06 25.3 0.0 1.5e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EPY53653.1 - 0.00016 21.3 0.1 0.0092 15.6 0.0 2.7 1 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EPY53653.1 - 0.00039 21.2 0.0 0.0011 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPY53653.1 - 0.0004 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPY53653.1 - 0.0062 15.6 0.0 0.036 13.1 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EPY53653.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EPY53653.1 - 0.031 13.3 0.1 0.65 9.0 0.0 2.5 2 1 1 3 3 3 0 Putative methyltransferase DUF3419 PF11899.3 EPY53653.1 - 0.062 12.0 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) TPMT PF05724.6 EPY53653.1 - 0.071 12.5 0.0 0.54 9.6 0.0 2.3 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Glycos_trans_3N PF02885.12 EPY53654.1 - 0.054 13.0 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain CactinC_cactus PF09732.4 EPY53655.1 - 3e-06 26.8 0.4 5.8e-06 25.9 0.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein zf-met PF12874.2 EPY53655.1 - 2e-05 24.6 1.2 2e-05 24.6 0.8 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EPY53655.1 - 0.021 14.0 0.3 0.038 13.2 0.2 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like zf-C2H2_jaz PF12171.3 EPY53655.1 - 0.6 10.3 2.5 1 9.6 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ribosomal_L34 PF00468.12 EPY53656.1 - 1.8e-19 69.1 9.3 2.7e-19 68.5 6.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 ABC1 PF03109.11 EPY53657.1 - 3.8e-24 84.9 0.3 8.9e-16 57.9 0.0 2.5 2 0 0 2 2 2 2 ABC1 family EpoR_lig-bind PF09067.5 EPY53658.1 - 0.14 12.1 1.9 0.18 11.8 1.0 1.5 1 1 0 1 1 1 0 Erythropoietin receptor, ligand binding Sds3 PF08598.6 EPY53659.1 - 6.3e-07 29.1 8.3 6.3e-07 29.1 5.8 3.5 1 1 1 3 3 3 2 Sds3-like DUF1162 PF06650.7 EPY53660.1 - 1.1e-63 215.0 5.6 5.7e-62 209.4 0.7 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EPY53660.1 - 3.5e-37 126.5 0.2 2.3e-36 123.9 0.2 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EPY53660.1 - 0.00082 19.4 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain RseA_N PF03872.8 EPY53660.1 - 0.014 15.6 0.0 0.065 13.5 0.0 2.1 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain ChAPs PF09295.5 EPY53661.1 - 3.2e-155 516.7 0.0 4.2e-155 516.3 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EPY53661.1 - 1.5e-05 24.5 1.5 0.0061 16.1 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EPY53661.1 - 8e-05 22.2 0.5 2.3 8.3 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY53661.1 - 0.0012 19.1 2.1 1.6 9.1 0.4 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPY53661.1 - 0.0015 18.1 0.0 3.1 7.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EPY53661.1 - 0.0023 18.0 1.5 0.41 10.8 0.4 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EPY53661.1 - 0.0054 17.2 3.2 6.1 7.7 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPY53661.1 - 0.014 16.0 0.4 0.68 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53661.1 - 0.16 11.9 1.5 1.8 8.5 0.1 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat ATP-synt_Eps PF04627.8 EPY53662.1 - 3.2e-17 61.8 0.6 3.9e-17 61.5 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain TPR_2 PF07719.12 EPY53663.1 - 1.4e-07 30.9 6.4 0.058 13.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPY53663.1 - 1.4e-07 30.7 6.0 0.0029 17.2 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPY53663.1 - 2.2e-07 30.4 4.5 0.16 11.6 0.0 5.3 5 0 0 5 5 5 2 TPR repeat TPR_6 PF13174.1 EPY53663.1 - 0.0003 21.0 1.2 2.6 8.6 0.0 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53663.1 - 0.00065 19.5 1.2 2.2 8.3 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPY53663.1 - 0.00086 18.8 7.9 0.038 13.6 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPY53663.1 - 0.0057 16.3 0.4 3.6 7.6 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPY53663.1 - 0.0066 16.9 0.2 37 5.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Hira PF07569.6 EPY53664.1 - 2.4e-63 213.2 0.0 4.6e-63 212.3 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EPY53664.1 - 7.1e-44 146.1 29.1 8.8e-10 38.0 0.3 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EPY53664.1 - 9.7e-09 34.5 1.7 9.7e-09 34.5 1.2 2.2 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 EPY53664.1 - 0.00015 21.3 0.5 0.49 10.1 0.1 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EPY53664.1 - 0.017 14.8 0.2 0.55 9.9 0.0 3.3 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Plectin PF00681.15 EPY53664.1 - 0.062 12.8 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Plectin repeat PUA PF01472.15 EPY53665.1 - 3.6e-19 68.2 0.2 5.6e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 PUA domain HAT PF02184.11 EPY53666.1 - 9.3e-27 92.4 61.3 1e-17 63.5 5.0 12.3 13 2 0 13 13 12 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EPY53666.1 - 2.9e-25 86.4 8.9 0.0033 17.9 0.0 11.5 5 3 8 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 EPY53666.1 - 1.6e-19 69.9 0.0 6e-06 26.4 0.0 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 EPY53666.1 - 6.9e-15 55.5 21.3 0.0013 18.5 0.3 6.9 4 3 3 7 7 7 4 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EPY53666.1 - 1.2e-14 54.4 18.1 0.00011 22.8 0.0 8.3 7 2 2 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 EPY53666.1 - 1.3e-13 49.6 9.7 0.0059 16.4 0.0 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPY53666.1 - 4.7e-08 32.5 7.8 0.033 13.8 0.0 6.3 4 2 3 7 7 7 2 TPR repeat TPR_12 PF13424.1 EPY53666.1 - 5.3e-08 32.7 13.8 0.046 13.6 0.0 7.2 7 2 1 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY53666.1 - 5.6e-08 32.0 3.1 4.7 7.2 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPY53666.1 - 9e-07 28.9 9.6 3.8 8.1 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPY53666.1 - 1.3e-06 27.7 2.0 3.8 7.5 0.0 6.6 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPY53666.1 - 2.4e-06 26.8 8.7 0.21 10.6 0.2 5.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPY53666.1 - 1.4e-05 24.9 5.4 0.14 12.4 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPY53666.1 - 0.0005 19.5 2.1 1.6 8.5 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPY53666.1 - 0.0022 17.8 0.2 33 4.4 0.0 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.5 EPY53666.1 - 0.0065 15.3 18.4 0.22 10.3 0.1 6.0 2 1 3 5 5 5 2 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.7 EPY53666.1 - 0.011 15.5 17.8 1.1 9.0 2.3 5.7 4 3 1 5 5 5 0 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.6 EPY53666.1 - 9.1 6.1 18.5 1 9.1 0.0 7.0 6 2 2 8 8 8 0 U3 small nucleolar RNA-associated protein 6 zf-MYND PF01753.13 EPY53667.1 - 5.3e-07 29.3 21.9 1.1e-06 28.3 15.2 1.6 1 1 0 1 1 1 1 MYND finger Med10 PF09748.4 EPY53668.1 - 4.5e-30 104.0 0.7 5.2e-30 103.8 0.5 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Hormone_recep PF00104.25 EPY53668.1 - 0.0027 16.8 0.5 0.039 13.0 0.0 2.3 2 1 1 3 3 3 1 Ligand-binding domain of nuclear hormone receptor DUF433 PF04255.9 EPY53668.1 - 0.039 13.3 0.1 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF433) DHC_N1 PF08385.7 EPY53668.1 - 0.079 11.3 0.9 0.089 11.1 0.1 1.5 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 FANCF PF11107.3 EPY53668.1 - 0.11 11.6 0.2 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) NPV_P10 PF05531.7 EPY53668.1 - 0.31 11.3 1.6 0.7 10.1 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein IKKbetaNEMObind PF12179.3 EPY53669.1 - 0.22 11.3 1.7 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain VHS PF00790.14 EPY53670.1 - 4.6e-26 91.1 0.0 1.6e-25 89.3 0.0 1.9 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 EPY53670.1 - 3.2e-09 36.6 1.0 6.6e-09 35.6 0.7 1.4 1 0 0 1 1 1 1 GAT domain FKBP_N PF01346.13 EPY53670.1 - 0.23 11.5 1.0 8.1 6.5 0.2 2.3 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Arf PF00025.16 EPY53671.1 - 1.6e-66 222.8 0.0 1.8e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPY53671.1 - 7.5e-11 41.3 0.1 1.1e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EPY53671.1 - 7.7e-09 35.0 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPY53671.1 - 1.7e-06 27.9 0.0 5.5e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EPY53671.1 - 1.6e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY53671.1 - 2.3e-05 24.8 0.0 3.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EPY53671.1 - 0.00043 19.5 0.0 0.00045 19.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EPY53671.1 - 0.024 14.1 0.0 0.1 12.0 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF1840 PF08895.6 EPY53671.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) GTP_EFTU PF00009.22 EPY53671.1 - 0.11 11.9 0.0 7.4 5.9 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Med17 PF10156.4 EPY53673.1 - 5.4e-69 232.6 4.3 6.9e-69 232.3 2.9 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex A1_Propeptide PF07966.7 EPY53673.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 A1 Propeptide ChaC PF04752.7 EPY53674.1 - 3.8e-60 202.8 0.0 4.3e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein 4HBT PF03061.17 EPY53675.1 - 1.6e-13 50.5 0.0 2.2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Tfb2 PF03849.9 EPY53676.1 - 5.9e-146 485.7 0.0 8.4e-146 485.3 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EPY53676.1 - 0.00045 19.9 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Snf7 PF03357.16 EPY53677.1 - 2.7e-21 75.6 13.1 3.2e-21 75.4 9.1 1.2 1 0 0 1 1 1 1 Snf7 Herpes_glycop PF01528.11 EPY53677.1 - 0.015 14.0 0.4 0.021 13.5 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Ist1 PF03398.9 EPY53677.1 - 0.06 12.7 3.1 0.092 12.1 2.2 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF2498 PF10692.4 EPY53678.1 - 0.082 12.5 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) Longin PF13774.1 EPY53679.1 - 1.2e-17 63.1 0.0 1.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPY53679.1 - 3.5e-14 52.1 0.7 4.9e-14 51.6 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Imm43 PF15602.1 EPY53679.1 - 0.048 13.6 0.2 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 43 Sec63 PF02889.11 EPY53680.1 - 3.1e-145 483.2 4.2 1.9e-90 303.3 0.4 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPY53680.1 - 2.1e-55 186.7 4.5 1.9e-29 102.3 0.6 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EPY53680.1 - 2.2e-18 66.7 0.8 1.3e-09 38.1 0.2 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPY53680.1 - 1e-15 57.3 0.0 2.2e-06 27.4 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPY53680.1 - 8.2e-07 29.2 2.8 0.081 13.0 0.0 4.1 3 2 0 3 3 3 2 AAA domain PhoH PF02562.11 EPY53680.1 - 4.1e-05 22.9 0.1 0.0064 15.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein SNF2_N PF00176.18 EPY53680.1 - 5.5e-05 22.1 0.4 0.016 14.0 0.1 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_10 PF12846.2 EPY53680.1 - 0.0015 18.0 0.6 7.1 5.9 0.0 4.4 4 1 1 5 5 5 1 AAA-like domain AAA_19 PF13245.1 EPY53680.1 - 0.0018 17.9 0.0 2.7 7.8 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EPY53680.1 - 0.018 14.4 0.5 4.3 6.7 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_23 PF13476.1 EPY53680.1 - 0.57 10.4 7.5 10 6.3 0.0 4.2 4 0 0 4 4 4 0 AAA domain Bystin PF05291.6 EPY53681.1 - 9.8e-135 448.3 2.6 1.5e-134 447.7 0.2 1.9 2 0 0 2 2 2 1 Bystin Rota_VP2 PF05087.7 EPY53681.1 - 0.13 10.1 1.4 0.24 9.2 1.0 1.3 1 0 0 1 1 1 0 Rotavirus VP2 protein AvrE PF11725.3 EPY53681.1 - 1.5 5.7 10.3 1.9 5.3 7.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor SPRY PF00622.23 EPY53682.1 - 1.4e-13 50.9 0.3 4.7e-12 46.0 0.0 2.6 2 1 1 3 3 3 1 SPRY domain zf-DHHC PF01529.15 EPY53683.1 - 1.1e-33 116.1 13.6 1.1e-33 116.1 9.4 2.9 1 1 2 3 3 3 1 DHHC palmitoyltransferase Complex1_LYR_1 PF13232.1 EPY53684.1 - 7.8e-16 58.0 0.9 1.2e-15 57.4 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPY53684.1 - 1.3e-14 53.6 0.6 2.1e-14 53.0 0.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EPY53684.1 - 0.042 14.3 2.1 0.064 13.7 1.4 1.3 1 1 0 1 1 1 0 Complex1_LYR-like DUF747 PF05346.6 EPY53685.1 - 5.4e-113 377.3 13.8 8.2e-113 376.8 9.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family OSTbeta PF15048.1 EPY53685.1 - 0.011 15.7 0.1 0.054 13.5 0.0 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein 2OG-FeII_Oxy_2 PF13532.1 EPY53686.1 - 6e-42 143.6 0.0 2.5e-41 141.6 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPY53686.1 - 0.0013 19.0 0.0 0.0078 16.4 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EPY53686.1 - 0.008 16.6 0.0 0.024 15.1 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pex14_N PF04695.8 EPY53687.1 - 3.1e-21 75.8 1.9 6e-14 52.2 0.1 3.5 2 2 1 3 3 3 2 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EPY53687.1 - 5.9e-05 22.7 5.9 8.4e-05 22.2 4.1 1.3 1 0 0 1 1 1 1 IncA protein DUF1759 PF03564.10 EPY53687.1 - 0.00076 19.3 0.9 0.00076 19.3 0.7 2.4 2 1 1 3 3 2 1 Protein of unknown function (DUF1759) CENP-Q PF13094.1 EPY53687.1 - 0.0018 18.3 11.6 0.0036 17.3 8.0 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 EPY53687.1 - 0.0018 16.8 7.1 0.0029 16.1 4.9 1.2 1 0 0 1 1 1 1 AAA domain DUF1631 PF07793.6 EPY53687.1 - 0.0022 16.2 5.6 0.003 15.7 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) DUF3584 PF12128.3 EPY53687.1 - 0.0066 13.8 11.9 0.0084 13.5 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) RmuC PF02646.11 EPY53687.1 - 0.023 13.5 9.5 0.34 9.7 0.2 2.2 1 1 1 2 2 2 0 RmuC family Imm6 PF14434.1 EPY53687.1 - 0.036 13.7 5.0 1.3 8.7 3.5 2.5 1 1 0 1 1 1 0 Immunity protein Imm6 ISG65-75 PF11727.3 EPY53687.1 - 0.065 12.2 9.1 0.03 13.3 4.9 1.5 2 0 0 2 2 1 0 Invariant surface glycoprotein PilJ PF13675.1 EPY53687.1 - 0.071 13.4 8.4 0.1 12.9 2.9 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term TMP_2 PF06791.8 EPY53687.1 - 0.072 12.6 1.3 0.11 12.1 0.9 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein FUSC PF04632.7 EPY53687.1 - 0.079 11.3 5.0 0.098 11.0 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CHDCT2 PF08074.6 EPY53687.1 - 0.098 12.3 2.3 0.16 11.7 0.5 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Exonuc_VII_L PF02601.10 EPY53687.1 - 0.099 11.8 6.3 0.15 11.2 4.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0240 PF06784.6 EPY53687.1 - 0.2 11.3 4.2 0.32 10.6 2.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) BAR PF03114.13 EPY53687.1 - 0.24 10.8 8.8 0.77 9.2 6.1 1.8 1 1 0 1 1 1 0 BAR domain Reo_sigmaC PF04582.7 EPY53687.1 - 0.25 10.4 4.4 0.35 10.0 1.0 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Transposase_22 PF02994.9 EPY53687.1 - 0.25 9.7 7.9 0.6 8.5 5.5 1.5 1 1 0 1 1 1 0 L1 transposable element Phasin PF05597.6 EPY53687.1 - 0.25 11.0 8.5 0.43 10.3 5.9 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) P4Ha_N PF08336.6 EPY53687.1 - 0.27 11.0 7.7 3.9 7.3 0.7 2.8 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region SRP54_N PF02881.14 EPY53687.1 - 0.29 11.2 6.7 0.076 13.1 1.3 2.5 2 2 0 2 2 2 0 SRP54-type protein, helical bundle domain APG6 PF04111.7 EPY53687.1 - 0.29 10.1 13.6 0.46 9.4 9.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 LMBR1 PF04791.11 EPY53687.1 - 0.37 9.3 4.7 0.45 9.0 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SPX PF03105.14 EPY53687.1 - 0.39 10.4 8.8 0.86 9.3 6.1 1.6 1 0 0 1 1 1 0 SPX domain Spectrin PF00435.16 EPY53687.1 - 0.46 10.8 9.9 0.63 10.3 1.9 2.5 2 0 0 2 2 2 0 Spectrin repeat FlgN PF05130.7 EPY53687.1 - 0.65 10.2 15.0 1.7 8.8 2.2 2.2 1 1 1 2 2 2 0 FlgN protein Atg14 PF10186.4 EPY53687.1 - 0.78 8.6 12.3 1.2 8.0 8.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Acyl-CoA_dh_C PF12806.2 EPY53687.1 - 0.78 9.5 4.6 5.7 6.8 0.2 2.8 1 1 2 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Enkurin PF13864.1 EPY53687.1 - 0.83 9.8 10.8 2.2 8.5 0.5 2.9 1 1 0 2 2 2 0 Calmodulin-binding Mt_ATP-synt_B PF05405.9 EPY53687.1 - 0.85 9.0 8.0 6.5 6.1 5.2 2.3 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2076 PF09849.4 EPY53687.1 - 0.88 9.5 10.5 0.21 11.5 4.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF342 PF03961.8 EPY53687.1 - 1.2 7.4 9.9 2 6.7 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) CorA PF01544.13 EPY53687.1 - 1.5 7.7 10.9 2.3 7.1 7.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.7 EPY53687.1 - 1.7 8.3 17.3 5.2 6.8 2.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.1 EPY53687.1 - 1.7 8.9 14.5 6.3 7.1 3.8 2.8 1 1 2 3 3 3 0 Snapin/Pallidin DUF1664 PF07889.7 EPY53687.1 - 1.8 8.3 8.6 11 5.7 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pup PF05639.6 EPY53687.1 - 2.1 8.8 13.7 1.4 9.5 4.2 3.0 3 0 0 3 3 2 0 Pup-like protein GvpK PF05121.7 EPY53687.1 - 2.1 8.1 7.3 1.7 8.5 1.5 2.5 2 0 0 2 2 2 0 Gas vesicle protein K Fib_alpha PF08702.5 EPY53687.1 - 2.5 8.2 10.1 9.9 6.2 6.3 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.8 EPY53687.1 - 3 7.2 10.1 2.5 7.4 0.8 2.2 1 1 1 2 2 2 0 fzo-like conserved region Prefoldin PF02996.12 EPY53687.1 - 3.6 7.2 16.1 8.6 6.0 0.4 3.2 1 1 1 3 3 3 0 Prefoldin subunit HSCB_C PF07743.8 EPY53687.1 - 3.7 8.0 12.9 2.1 8.8 0.7 2.7 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain TraF_2 PF13729.1 EPY53687.1 - 3.8 6.2 6.3 9.6 4.9 4.4 1.7 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein Sec20 PF03908.8 EPY53687.1 - 4 7.2 10.1 6.5 6.5 0.4 2.7 2 1 0 3 3 2 0 Sec20 DUF2203 PF09969.4 EPY53687.1 - 4.7 7.4 5.7 53 4.0 4.0 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3552 PF12072.3 EPY53687.1 - 5.4 6.1 19.1 12 5.0 13.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Ribosomal_L29 PF00831.18 EPY53687.1 - 7.9 6.2 16.0 2.4 7.9 1.1 3.4 3 0 0 3 3 3 0 Ribosomal L29 protein TPD52 PF04201.10 EPY53687.1 - 8.3 6.1 10.8 4 7.1 3.5 2.3 1 1 1 2 2 2 0 Tumour protein D52 family NTP_transferase PF00483.18 EPY53688.1 - 2.9e-27 95.5 0.0 4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EPY53688.1 - 3.4e-11 42.1 3.5 9.4e-05 21.7 0.1 4.4 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPY53688.1 - 1.8e-08 34.6 0.0 6.7e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EPY53688.1 - 0.0056 15.3 2.3 0.035 12.6 0.5 2.1 2 0 0 2 2 2 1 L-fucokinase IspD PF01128.14 EPY53688.1 - 0.049 13.1 0.0 0.31 10.5 0.0 2.3 2 1 1 3 3 3 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase S4 PF01479.20 EPY53689.1 - 1.6e-11 43.4 0.9 2.1e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.1 EPY53689.1 - 0.00047 19.7 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 S4 domain RRM_1 PF00076.17 EPY53690.1 - 4.1e-17 61.5 0.0 5.9e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53690.1 - 7.1e-13 48.3 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53690.1 - 3.2e-06 26.8 0.0 5.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY53690.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DEAD PF00270.24 EPY53691.1 - 5.4e-10 39.0 0.0 9.9e-10 38.1 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY53691.1 - 0.0045 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY53691.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TRM PF02005.11 EPY53692.1 - 5e-146 486.4 0.0 6.4e-146 486.0 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EPY53692.1 - 2.9e-06 27.0 0.1 5.2e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EPY53692.1 - 0.0021 18.0 0.2 0.0071 16.3 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ribonuc_red_sm PF00268.16 EPY53693.1 - 4.8e-118 393.2 0.4 5.8e-118 392.9 0.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain MCM PF00493.18 EPY53694.1 - 9.6e-134 445.3 0.0 1.4e-133 444.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPY53694.1 - 6.3e-30 104.1 0.2 2.1e-28 99.2 0.1 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPY53694.1 - 1.6e-07 30.7 0.0 1.2e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPY53694.1 - 1e-06 28.5 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPY53694.1 - 0.013 15.1 0.0 0.049 13.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPY53694.1 - 0.042 13.3 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EPY53694.1 - 0.087 12.5 0.2 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_8 PF12780.2 EPY53694.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Cytokin_check_N PF10407.4 EPY53695.1 - 1.4e-17 63.0 0.7 2.7e-17 62.1 0.5 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus AT_hook PF02178.14 EPY53695.1 - 0.036 13.7 4.4 0.11 12.2 3.1 1.9 1 0 0 1 1 1 0 AT hook motif Pescadillo_N PF06732.6 EPY53696.1 - 1.6e-129 431.1 1.8 1.6e-129 431.1 1.3 2.4 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EPY53696.1 - 5.6e-10 39.2 0.0 1.7e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AA_kinase PF00696.23 EPY53697.1 - 4.4e-41 141.0 0.0 6.1e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EPY53697.1 - 2e-11 43.1 0.4 3.8e-08 32.6 0.0 2.9 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EPY53697.1 - 3.8e-11 42.3 0.9 7.8e-10 38.1 0.1 2.7 2 0 0 2 2 2 1 ACT domain DUF2496 PF10689.4 EPY53697.1 - 0.032 13.8 0.3 13 5.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) Syja_N PF02383.13 EPY53698.1 - 1.3e-86 290.3 3.2 1.5e-86 290.0 2.2 1.1 1 0 0 1 1 1 1 SacI homology domain ABC2_membrane_4 PF12730.2 EPY53698.1 - 0.018 14.2 2.9 0.028 13.5 2.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein YfhO PF09586.5 EPY53698.1 - 0.022 12.7 0.5 0.041 11.9 0.3 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO WD40 PF00400.27 EPY53699.1 - 1.9e-16 59.2 13.9 0.00058 19.6 0.0 9.0 10 0 0 10 10 10 5 WD domain, G-beta repeat Acid_PPase PF12689.2 EPY53700.1 - 2.4e-60 203.0 0.0 2.7e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EPY53700.1 - 0.0039 17.4 0.7 0.039 14.1 0.0 2.1 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EPY53700.1 - 0.004 16.8 0.1 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Fungal_trans PF04082.13 EPY53701.1 - 1.3e-12 47.1 2.1 1.3e-12 47.1 1.4 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPY53701.1 - 3.5e-07 30.0 5.2 6.9e-07 29.0 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C4H2 PF10146.4 EPY53702.1 - 0.00041 20.4 8.8 0.00041 20.4 6.1 2.5 2 1 0 2 2 2 1 Zinc finger-containing protein DUF3450 PF11932.3 EPY53702.1 - 0.0036 16.6 5.2 0.0036 16.6 3.6 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3450) Alph_Pro_TM PF09608.5 EPY53702.1 - 0.05 13.1 0.2 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) NPV_P10 PF05531.7 EPY53702.1 - 0.1 12.8 8.7 2.3 8.5 0.0 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FAM110_C PF14160.1 EPY53702.1 - 0.47 11.4 0.1 0.47 11.4 0.1 2.8 3 0 0 3 3 3 0 Centrosome-associated C terminus Synaptobrevin PF00957.16 EPY53702.1 - 1.5 8.4 6.3 0.31 10.6 0.4 2.6 2 1 1 3 3 3 0 Synaptobrevin Chorismate_bind PF00425.13 EPY53703.1 - 3.4e-72 242.8 0.0 6.6e-72 241.9 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EPY53703.1 - 4.2e-30 104.6 0.0 6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EPY53703.1 - 7.8e-18 64.8 0.0 1.6e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EPY53703.1 - 5.1e-09 35.8 0.0 9.2e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 DUF1451 PF07295.6 EPY53703.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Stc1 PF12898.2 EPY53704.1 - 5.2e-15 55.2 8.6 6e-15 55.0 5.4 1.5 1 1 0 1 1 1 1 Stc1 domain zf-piccolo PF05715.8 EPY53704.1 - 0.53 10.3 0.1 0.53 10.3 0.1 2.9 2 1 1 3 3 3 0 Piccolo Zn-finger RNHCP PF12647.2 EPY53704.1 - 0.95 9.3 7.7 1.6 8.5 2.9 2.5 2 1 0 2 2 2 0 RNHCP domain Elf1 PF05129.8 EPY53704.1 - 1.5 8.5 11.8 3.4 7.4 4.0 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HECT PF00632.20 EPY53705.1 - 1.3e-82 277.4 0.5 2.2e-82 276.7 0.4 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) 5_nucleotid_C PF02872.13 EPY53705.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Pro_isomerase PF00160.16 EPY53707.1 - 4.2e-45 153.7 0.2 5.1e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Atg8 PF02991.11 EPY53708.1 - 2.5e-50 168.7 0.2 2.9e-50 168.5 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EPY53708.1 - 1.5e-06 28.2 0.0 1.9e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 zf-C3HC4 PF00097.20 EPY53709.1 - 5.6e-07 29.1 2.3 9e-06 25.2 2.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY53709.1 - 1.9e-05 24.5 4.9 9.7e-05 22.3 3.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPY53709.1 - 9e-05 22.2 6.9 0.00021 21.0 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPY53709.1 - 0.00044 19.8 7.0 0.00093 18.8 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPY53709.1 - 0.001 18.8 1.4 0.001 18.8 0.9 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PAM2 PF07145.10 EPY53709.1 - 0.098 12.2 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-RING_5 PF14634.1 EPY53709.1 - 0.18 11.5 10.4 0.65 9.7 7.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 EPY53709.1 - 0.49 10.5 3.9 2 8.5 2.7 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPY53709.1 - 1.2 8.8 5.5 0.41 10.4 0.8 2.4 2 0 0 2 2 2 0 RING-type zinc-finger UCH PF00443.24 EPY53710.1 - 4.3e-51 173.5 0.0 6.5e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY53710.1 - 3e-15 56.4 0.0 1.7e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C28 PF05408.6 EPY53710.1 - 0.097 12.1 0.5 12 5.3 0.1 2.3 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase FlgM PF04316.8 EPY53710.1 - 0.12 12.2 0.2 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM ER_lumen_recept PF00810.13 EPY53711.1 - 3.5e-51 173.5 10.0 5.1e-51 173.0 6.9 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EPY53711.1 - 0.0026 17.2 9.6 0.054 13.0 0.8 3.5 2 1 1 3 3 3 2 PQ loop repeat YfhO PF09586.5 EPY53711.1 - 3 5.7 15.3 3.6 5.4 10.6 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Nol1_Nop2_Fmu PF01189.12 EPY53714.1 - 1.8e-99 332.6 0.0 2.8e-99 332.0 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EPY53714.1 - 0.00098 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein SPT16 PF08644.6 EPY53715.1 - 9.7e-58 194.3 0.0 3.4e-57 192.5 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EPY53715.1 - 2.1e-51 173.6 0.2 2.1e-51 173.6 0.1 1.9 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EPY53715.1 - 2.8e-27 95.6 0.0 5.3e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EPY53715.1 - 2.2e-22 78.8 0.0 7.4e-22 77.1 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 EPY53715.1 - 0.23 11.0 0.0 0.49 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Phos_pyr_kin PF08543.7 EPY53716.1 - 9e-80 267.4 0.1 1.4e-79 266.8 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EPY53716.1 - 1.3e-42 145.9 0.0 2.1e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 EPY53716.1 - 0.00062 19.0 0.3 0.003 16.7 0.0 2.1 3 0 0 3 3 3 1 Hydroxyethylthiazole kinase family PfkB PF00294.19 EPY53716.1 - 0.032 13.3 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 pfkB family carbohydrate kinase IRF-2BP1_2 PF11261.3 EPY53716.1 - 0.19 11.2 1.5 0.4 10.1 0.1 2.3 3 0 0 3 3 3 0 Interferon regulatory factor 2-binding protein zinc finger Phos_pyr_kin PF08543.7 EPY53717.1 - 3.8e-75 252.2 0.2 5.6e-75 251.6 0.2 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EPY53717.1 - 1.1e-17 64.4 0.0 2.4e-17 63.3 0.0 1.5 2 0 0 2 2 2 1 TENA/THI-4/PQQC family PfkB PF00294.19 EPY53717.1 - 0.0065 15.6 0.3 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Ku_PK_bind PF08785.6 EPY53717.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Ku C terminal domain like DEAD PF00270.24 EPY53718.1 - 2.8e-44 150.5 0.0 3.5e-43 147.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY53718.1 - 4.8e-28 96.8 0.0 1e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY53718.1 - 1.9e-05 24.5 0.0 0.00032 20.5 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EPY53718.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain HGD-D PF06050.8 EPY53718.1 - 0.17 10.6 0.0 0.37 9.5 0.0 1.5 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DWNN PF08783.6 EPY53719.1 - 3.5e-33 113.3 0.2 5.9e-33 112.6 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EPY53719.1 - 6.7e-05 22.2 7.0 0.00023 20.5 4.9 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EPY53719.1 - 0.00016 21.5 11.7 0.00016 21.5 8.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY53719.1 - 0.002 17.7 10.1 0.002 17.7 7.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Thioredoxin_4 PF13462.1 EPY53719.1 - 0.016 15.1 3.2 0.017 15.1 0.0 2.5 3 1 0 3 3 3 0 Thioredoxin zf-RING_2 PF13639.1 EPY53719.1 - 0.02 14.7 12.1 0.02 14.7 8.4 1.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.1 EPY53719.1 - 0.029 14.1 2.8 0.052 13.3 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EPY53719.1 - 0.032 13.9 13.3 0.067 12.8 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 EPY53719.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.1 3 0 0 3 3 1 0 Zinc knuckle zf-RING_5 PF14634.1 EPY53719.1 - 0.55 10.0 18.8 0.034 13.8 9.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-CCHC PF00098.18 EPY53719.1 - 1.3 9.1 6.4 0.12 12.3 0.6 2.1 2 0 0 2 2 2 0 Zinc knuckle HypA PF01155.14 EPY53719.1 - 5.6 6.6 6.8 16 5.2 3.9 2.3 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_4 PF14570.1 EPY53719.1 - 6.7 6.3 12.1 14 5.3 8.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DNA_pol_E_B PF04042.11 EPY53720.1 - 2.4e-50 170.7 0.3 3.4e-50 170.1 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Vac7 PF12751.2 EPY53721.1 - 1.7e-07 30.4 13.4 5.3e-07 28.8 9.3 1.9 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 DUF2486 PF10667.4 EPY53721.1 - 0.47 10.9 3.8 0.73 10.3 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2486) CENP-H PF05837.7 EPY53722.1 - 1.2e-12 47.8 0.3 1.2e-12 47.8 0.2 2.2 2 1 0 2 2 2 1 Centromere protein H (CENP-H) Lzipper-MIP1 PF14389.1 EPY53722.1 - 0.0059 16.6 0.9 0.0059 16.6 0.6 2.0 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Put_Phosphatase PF06888.7 EPY53722.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative Phosphatase Uds1 PF15456.1 EPY53722.1 - 1.8 8.5 7.7 0.067 13.1 0.5 2.2 3 0 0 3 3 3 0 Up-regulated During Septation NTF2 PF02136.15 EPY53723.1 - 1.8e-28 99.2 0.0 3.2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EPY53723.1 - 6.2e-11 41.7 0.0 1.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53723.1 - 2.8e-10 40.0 0.0 5.5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPY53723.1 - 0.023 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.1 EPY53723.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 EPY53723.1 - 0.089 12.1 22.2 0.13 11.6 15.4 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EPY53723.1 - 1.5 8.6 10.7 2.1 8.1 7.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit U3_snoRNA_assoc PF08297.6 EPY53724.1 - 0.0028 17.8 27.9 2.6 8.3 19.3 3.5 1 1 0 1 1 1 1 U3 snoRNA associated GEMIN8 PF15348.1 EPY53724.1 - 0.63 10.0 17.9 0.96 9.4 12.4 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF3499 PF12005.3 EPY53724.1 - 1.9 8.6 10.2 1.9 8.6 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3499) FLO_LFY PF01698.11 EPY53724.1 - 7.2 5.3 13.2 8.3 5.1 9.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Xpo1 PF08389.7 EPY53725.1 - 9.2e-35 119.7 2.8 9.2e-35 119.7 1.9 3.4 4 0 0 4 4 4 1 Exportin 1-like protein Gon7 PF08738.5 EPY53725.1 - 0.008 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Gon7 family HEAT PF02985.17 EPY53725.1 - 0.091 12.8 0.0 28 5.1 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat LCM PF04072.9 EPY53726.1 - 3e-26 92.1 0.0 4.5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SET PF00856.23 EPY53727.1 - 9.6e-13 48.7 0.6 6.7e-11 42.7 0.3 2.8 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 EPY53727.1 - 3.4e-10 39.6 13.3 3.4e-10 39.6 9.2 2.6 2 1 0 2 2 2 1 MYND finger Ribosomal_60s PF00428.14 EPY53728.1 - 1.4e-27 95.8 11.2 1.6e-27 95.6 7.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pro_CA PF00484.14 EPY53729.1 - 1e-48 165.1 1.2 1.3e-47 161.5 0.1 2.0 2 0 0 2 2 2 1 Carbonic anhydrase TORC_M PF12885.2 EPY53729.1 - 0.021 14.5 0.4 0.04 13.6 0.3 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Ribosomal_L4 PF00573.17 EPY53731.1 - 1e-44 152.2 1.4 1.4e-44 151.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EPY53731.1 - 1.3e-27 95.4 2.9 1.3e-27 95.4 2.0 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PIF1 PF05970.9 EPY53731.1 - 0.042 12.7 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF4201 PF13870.1 EPY53732.1 - 0.021 14.2 18.4 0.045 13.1 12.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) APG6 PF04111.7 EPY53732.1 - 0.029 13.4 18.9 0.054 12.5 13.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ECM11 PF15463.1 EPY53732.1 - 0.12 12.6 11.0 0.23 11.7 6.3 2.3 2 1 0 2 2 2 0 Extracellular mutant protein 11 DUF4200 PF13863.1 EPY53732.1 - 0.13 12.2 22.4 0.098 12.6 2.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) MitMem_reg PF13012.1 EPY53732.1 - 0.47 10.5 15.7 0.042 13.9 3.8 3.0 1 1 2 3 3 3 0 Maintenance of mitochondrial structure and function V_ATPase_I PF01496.14 EPY53732.1 - 0.48 8.2 12.4 0.64 7.7 8.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.1 EPY53732.1 - 2.1 8.1 11.0 0.19 11.5 1.9 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) IncA PF04156.9 EPY53732.1 - 5.6 6.5 27.8 16 5.0 17.3 2.3 1 1 1 2 2 2 0 IncA protein Rpp20 PF12328.3 EPY53733.1 - 6.1e-12 45.4 0.4 1.5e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EPY53733.1 - 0.0034 16.9 0.1 0.0054 16.2 0.1 1.4 1 0 0 1 1 1 1 Alba Kdo PF06293.9 EPY53733.1 - 0.082 11.9 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family M16C_assoc PF08367.6 EPY53733.1 - 0.13 11.1 0.5 0.88 8.3 0.1 2.0 2 0 0 2 2 2 0 Peptidase M16C associated Ribosomal_S13 PF00416.17 EPY53735.1 - 2.8e-40 137.0 2.8 3.4e-40 136.8 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPY53735.1 - 0.00085 17.9 0.0 0.0013 17.4 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EPY53735.1 - 0.0093 15.9 0.2 0.027 14.5 0.0 1.8 2 1 0 2 2 2 1 Helix-hairpin-helix motif dCMP_cyt_deam_1 PF00383.17 EPY53736.1 - 1.3e-25 88.9 1.7 4.4e-25 87.3 1.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region PRK PF00485.13 EPY53736.1 - 0.0066 16.0 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Bd3614-deam PF14439.1 EPY53736.1 - 0.0088 15.8 0.1 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase MafB19-deam PF14437.1 EPY53736.1 - 0.044 13.4 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 MafB19-like deaminase AAA_17 PF13207.1 EPY53736.1 - 0.16 12.7 0.0 0.29 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain PCNA_N PF00705.13 EPY53737.1 - 8.9e-59 196.5 3.8 1.9e-58 195.5 2.4 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EPY53737.1 - 3.2e-53 179.0 0.0 5.8e-53 178.1 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EPY53737.1 - 1.5e-07 30.8 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EPY53737.1 - 0.0003 19.8 0.2 0.0022 16.9 0.1 2.1 1 1 1 2 2 2 1 Hus1-like protein DUF2247 PF10004.4 EPY53737.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) AAA_2 PF07724.9 EPY53738.1 - 3.7e-51 173.4 0.0 1e-49 168.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EPY53738.1 - 8.6e-28 97.1 0.0 3.3e-15 56.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EPY53738.1 - 1.1e-23 82.9 0.2 3.5e-23 81.3 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EPY53738.1 - 3.6e-17 62.0 0.1 6.4e-09 35.6 0.0 3.3 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 EPY53738.1 - 1.2e-15 57.4 0.1 4.4e-10 39.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPY53738.1 - 7.9e-15 55.3 9.4 2.9e-05 24.1 0.0 5.3 4 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 EPY53738.1 - 4.2e-13 49.5 1.0 0.00013 22.1 0.0 4.5 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EPY53738.1 - 3e-10 39.8 0.0 1.2e-06 28.1 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPY53738.1 - 4.5e-08 32.7 0.0 0.0048 16.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EPY53738.1 - 6.8e-07 30.1 7.2 0.053 14.3 0.0 4.4 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EPY53738.1 - 1e-06 28.0 0.0 0.016 14.3 0.0 3.3 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EPY53738.1 - 1.1e-05 25.7 3.8 0.01 16.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EPY53738.1 - 2.4e-05 23.8 0.7 0.16 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EPY53738.1 - 5.4e-05 22.3 0.5 0.039 13.0 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 EPY53738.1 - 9.1e-05 22.1 0.7 0.37 10.5 0.0 3.6 5 0 0 5 5 2 2 Part of AAA domain AAA_3 PF07726.6 EPY53738.1 - 0.00013 21.5 0.1 0.055 13.0 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPY53738.1 - 0.00015 21.7 0.3 0.98 9.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain ABC_tran PF00005.22 EPY53738.1 - 0.00015 22.0 0.4 0.13 12.5 0.0 3.6 3 1 1 4 4 3 1 ABC transporter RNA_helicase PF00910.17 EPY53738.1 - 0.00019 21.5 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 EPY53738.1 - 0.00027 20.8 0.0 0.18 11.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 EPY53738.1 - 0.00029 19.8 0.4 0.0045 15.9 0.2 3.0 3 1 0 3 3 3 1 Type II/IV secretion system protein AAA_21 PF13304.1 EPY53738.1 - 0.00088 19.3 0.0 0.4 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EPY53738.1 - 0.0011 18.7 5.9 0.25 10.9 0.2 4.3 4 1 0 4 4 3 1 Archaeal ATPase AAA_24 PF13479.1 EPY53738.1 - 0.0014 18.2 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPY53738.1 - 0.005 16.0 0.0 2.9 7.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EPY53738.1 - 0.0094 15.6 0.0 3.2 7.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EPY53738.1 - 0.011 15.1 0.0 8.5 5.9 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain NACHT PF05729.7 EPY53738.1 - 0.013 15.1 0.3 0.95 9.1 0.0 3.0 3 0 0 3 3 3 0 NACHT domain AAA_10 PF12846.2 EPY53738.1 - 0.017 14.5 3.4 3.7 6.8 0.0 4.4 4 1 1 5 5 5 0 AAA-like domain PhoH PF02562.11 EPY53738.1 - 0.021 14.0 0.0 1.1 8.4 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein UPF0079 PF02367.12 EPY53738.1 - 0.024 14.2 0.0 26 4.4 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EPY53738.1 - 0.028 13.3 0.0 1.8 7.4 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 EPY53738.1 - 0.031 14.1 0.0 0.18 11.7 0.0 2.2 3 0 0 3 3 2 0 Torsin Sigma54_activ_2 PF14532.1 EPY53738.1 - 0.053 13.5 0.0 4.4 7.3 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain IncA PF04156.9 EPY53738.1 - 0.85 9.1 7.8 2.4 7.7 5.4 1.7 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EPY53738.1 - 2.9 6.8 5.5 5.2 6.0 3.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 SIR2 PF02146.12 EPY53739.1 - 3.5e-62 209.2 0.0 5.3e-62 208.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EPY53739.1 - 1.1e-06 28.2 0.8 3.6e-06 26.6 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EPY53739.1 - 0.0068 16.1 0.0 0.97 9.1 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Zip PF02535.17 EPY53740.1 - 1.6e-43 148.9 4.9 4e-43 147.6 3.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Sulfakinin PF08257.6 EPY53740.1 - 0.94 9.5 3.1 3.4 7.8 2.2 2.0 1 0 0 1 1 1 0 Sulfakinin family Alpha-amylase PF00128.19 EPY53741.1 - 1.5e-25 90.3 1.5 1.7e-19 70.3 0.1 3.2 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EPY53741.1 - 3.9e-15 56.0 0.2 7.5e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EPY53741.1 - 5.7e-06 25.8 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EPY53741.1 - 0.012 16.1 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain Dna2 PF08696.6 EPY53742.1 - 5.7e-59 198.9 1.5 8.9e-59 198.2 0.2 2.0 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 EPY53742.1 - 5.9e-49 166.1 0.1 1.4e-48 164.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPY53742.1 - 1.7e-37 129.2 8.7 1.7e-19 70.3 0.0 3.9 3 2 1 4 4 3 2 AAA domain AAA_19 PF13245.1 EPY53742.1 - 2.5e-10 39.9 0.0 6e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPY53742.1 - 7.5e-08 32.1 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPY53742.1 - 1.1e-06 28.3 0.8 0.42 10.0 0.0 4.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EPY53742.1 - 0.00018 21.2 0.0 0.00048 19.8 0.0 1.8 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EPY53742.1 - 0.00049 19.4 0.0 0.00049 19.4 0.0 3.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 EPY53742.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EPY53742.1 - 0.0062 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EPY53742.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EPY53742.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 EPY53742.1 - 0.015 15.1 0.7 0.015 15.1 0.5 3.1 3 1 0 3 3 3 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EPY53742.1 - 0.03 14.4 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EPY53742.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EPY53742.1 - 0.12 11.1 0.0 0.25 10.0 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 EPY53742.1 - 0.2 11.0 0.1 0.43 9.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M22 PF00814.20 EPY53743.1 - 2e-86 289.7 0.0 2.4e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family UPF0020 PF01170.13 EPY53744.1 - 4.8e-11 42.5 0.0 1.3e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EPY53744.1 - 2.8e-10 40.2 0.0 4.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EPY53744.1 - 0.0052 15.9 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 EPY53744.1 - 0.029 13.8 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 DNA methylase TPR_2 PF07719.12 EPY53745.1 - 2.9e-09 36.1 3.8 0.0028 17.4 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPY53745.1 - 1.2e-07 31.2 8.5 0.00069 19.2 0.2 3.8 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.1 EPY53745.1 - 4.8e-07 29.0 4.4 0.00046 19.7 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY53745.1 - 2.6e-06 26.7 5.1 0.067 12.8 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPY53745.1 - 3.9e-06 26.6 0.9 0.021 15.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPY53745.1 - 2e-05 25.1 2.4 0.21 12.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPY53745.1 - 6.1e-05 23.2 11.1 0.0033 17.7 0.4 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53745.1 - 0.0002 21.2 7.0 0.57 10.1 0.2 4.7 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPY53745.1 - 0.00024 21.4 6.0 0.18 12.5 0.1 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY53745.1 - 0.00025 20.5 1.2 0.85 9.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 EPY53745.1 - 0.00065 19.6 3.8 0.22 11.4 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPY53745.1 - 0.0026 17.6 0.8 21 5.2 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPY53745.1 - 0.02 14.9 10.0 0.37 10.9 0.3 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EPY53745.1 - 0.077 12.8 2.9 0.66 9.8 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY53745.1 - 0.17 12.4 4.9 13 6.5 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EPY53746.1 - 1.7e-67 228.3 0.5 3.4e-67 227.3 0.0 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EPY53746.1 - 3.8e-10 39.2 16.8 4.8e-05 22.9 2.1 5.5 4 1 2 6 6 6 4 TPR repeat TPR_16 PF13432.1 EPY53746.1 - 1.9e-08 34.7 0.0 0.11 13.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPY53746.1 - 9.1e-07 28.6 0.1 0.36 10.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPY53746.1 - 1.1e-06 28.7 0.2 11 7.0 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPY53746.1 - 1.4e-06 27.6 6.7 0.0033 17.1 0.2 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPY53746.1 - 2.4e-06 26.9 8.7 0.015 14.8 0.3 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPY53746.1 - 6.2e-06 25.7 18.9 0.005 16.6 0.1 7.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPY53746.1 - 0.00018 21.7 0.4 5.4 7.4 0.0 5.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53746.1 - 0.00022 21.1 9.3 0.13 12.2 0.3 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPY53746.1 - 0.0024 17.5 0.6 9.9 6.2 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPY53746.1 - 0.013 14.6 1.0 0.097 11.7 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPY53746.1 - 0.044 14.0 13.7 0.11 12.7 0.0 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EPY53746.1 - 0.065 13.3 0.1 0.065 13.3 0.1 5.7 3 3 5 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 PMI_typeI PF01238.16 EPY53747.1 - 2.1e-114 382.3 0.0 2.5e-114 382.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EPY53747.1 - 0.00018 20.9 0.0 0.065 12.7 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Auxin_BP PF02041.11 EPY53747.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein SUN PF03856.8 EPY53748.1 - 6.9e-94 313.7 18.8 8e-94 313.5 13.0 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) WD40 PF00400.27 EPY53749.1 - 1.6e-47 157.6 13.1 2.7e-11 42.8 0.0 7.0 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EPY53749.1 - 8e-10 38.2 0.4 2.1e-09 36.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPY53749.1 - 1.2e-08 34.3 2.3 2.3e-08 33.4 0.6 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EPY53749.1 - 1.2e-07 30.2 5.5 0.087 10.9 0.1 4.7 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PRANC PF09372.5 EPY53749.1 - 0.0031 17.4 2.1 0.27 11.2 0.0 3.5 2 1 1 3 3 3 1 PRANC domain PQQ_2 PF13360.1 EPY53749.1 - 0.0051 16.2 1.7 9.7 5.5 0.1 3.7 2 2 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 EPY53749.1 - 0.12 12.6 0.8 30 5.0 0.0 3.8 3 1 0 3 3 3 0 PQQ-like domain PHD PF00628.24 EPY53750.1 - 4.3e-07 29.5 10.2 9.2e-07 28.4 7.1 1.6 1 0 0 1 1 1 1 PHD-finger HORMA PF02301.13 EPY53750.1 - 0.00021 20.8 5.1 0.00021 20.8 3.6 1.7 1 1 0 1 1 1 1 HORMA domain PHD_2 PF13831.1 EPY53750.1 - 0.0024 17.1 5.6 0.0053 16.0 3.9 1.6 1 0 0 1 1 1 1 PHD-finger RNA_polI_A14 PF08203.6 EPY53751.1 - 9.5e-16 57.8 1.9 1.2e-15 57.4 0.1 2.1 1 1 1 2 2 2 1 Yeast RNA polymerase I subunit RPA14 CAF-1_p150 PF11600.3 EPY53751.1 - 0.00055 19.3 16.8 0.00066 19.1 11.6 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 EPY53751.1 - 1.1 9.0 10.5 1.1 9.0 7.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EPY53751.1 - 2.5 7.4 15.2 2.7 7.3 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 EPY53751.1 - 2.5 7.8 10.4 4.1 7.1 7.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3340 PF11818.3 EPY53751.1 - 2.8 7.9 13.0 23 4.9 8.9 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) NARP1 PF12569.3 EPY53751.1 - 4.7 5.8 18.8 6 5.5 13.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U79_P34 PF03064.11 EPY53751.1 - 5.1 6.5 14.7 6.2 6.2 9.8 1.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Acyltransferase PF01553.16 EPY53752.1 - 7.8e-12 44.7 0.0 7.2e-11 41.6 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase TRAPP PF04051.11 EPY53753.1 - 3.4e-46 156.5 0.0 4.2e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dynamin_N PF00350.18 EPY53754.1 - 8.1e-42 142.8 0.5 3.6e-41 140.7 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EPY53754.1 - 1.2e-09 37.3 1.3 2.8e-06 26.3 0.1 2.6 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EPY53754.1 - 0.00047 20.0 0.0 0.0017 18.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPY53754.1 - 0.0016 18.8 0.0 0.0052 17.2 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EPY53754.1 - 0.056 13.4 0.7 0.49 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain zf-CCCH PF00642.19 EPY53755.1 - 2.2e-22 78.2 16.8 2e-12 46.4 2.5 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPY53755.1 - 1.8 8.6 16.9 0.093 12.7 3.0 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type PSP1 PF04468.7 EPY53756.1 - 2.8e-34 116.9 0.6 4.6e-34 116.2 0.4 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region NUC173 PF08161.7 EPY53757.1 - 1.6e-08 34.1 0.9 0.0033 16.8 0.0 3.2 2 1 1 3 3 3 2 NUC173 domain HEAT PF02985.17 EPY53757.1 - 0.024 14.6 2.3 15 5.9 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat HMGL-like PF00682.14 EPY53758.1 - 1.4e-74 250.7 0.5 2.1e-74 250.1 0.1 1.5 2 0 0 2 2 2 1 HMGL-like DUF2624 PF11116.3 EPY53758.1 - 0.013 15.9 0.1 8 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Ribosomal_L16 PF00252.13 EPY53759.1 - 1.9e-33 115.0 0.3 2.4e-33 114.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Cellulase PF00150.13 EPY53761.1 - 2.2e-15 56.6 9.5 3e-15 56.1 6.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Med4 PF10018.4 EPY53762.1 - 1.6e-22 79.8 5.5 2.2e-22 79.4 3.8 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin_2 PF14523.1 EPY53762.1 - 0.0091 16.0 1.8 0.024 14.6 1.2 1.7 1 0 0 1 1 1 1 Syntaxin-like protein Dict-STAT-coil PF09267.5 EPY53762.1 - 0.044 13.9 2.5 0.096 12.9 1.7 1.5 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DUF342 PF03961.8 EPY53762.1 - 0.054 11.9 1.0 0.094 11.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3702 PF12486.3 EPY53762.1 - 0.086 12.5 3.4 4.6 6.9 0.0 3.2 2 2 1 3 3 3 0 ImpA domain protein Reo_sigmaC PF04582.7 EPY53762.1 - 0.13 11.3 2.3 0.24 10.5 1.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PCI PF01399.22 EPY53763.1 - 1.2e-11 44.8 0.1 3.4e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 PCI domain Apc3 PF12895.2 EPY53763.1 - 0.0073 16.4 0.1 0.016 15.3 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 EMP70 PF02990.11 EPY53764.1 - 1.1e-189 631.2 13.9 1.5e-189 630.8 9.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 UQ_con PF00179.21 EPY53765.1 - 7.6e-42 142.0 0.0 8.4e-42 141.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rav1p_C PF12234.3 EPY53766.1 - 5.4e-152 507.1 2.2 8.8e-152 506.4 1.5 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal Histone PF00125.19 EPY53767.1 - 6.8e-32 109.4 0.1 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPY53767.1 - 6.3e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPY53767.1 - 0.0024 17.8 0.2 0.0056 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPY53767.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EPY53768.1 - 7.2e-15 54.8 0.4 8.7e-15 54.6 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY53768.1 - 7.1e-06 25.9 0.1 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPY53768.1 - 5.8e-05 23.1 0.1 8.2e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EPY53768.1 - 8.5e-05 22.4 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 EPY53768.1 - 0.012 14.8 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EPY53768.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated DUF1819 PF08849.6 EPY53768.1 - 0.1 12.0 0.6 0.36 10.2 0.1 1.8 1 1 1 2 2 2 0 Putative inner membrane protein (DUF1819) TFIID_20kDa PF03847.8 EPY53768.1 - 0.1 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A zf-C2H2 PF00096.21 EPY53769.1 - 1.2e-08 34.7 5.6 0.00046 20.3 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY53769.1 - 3.3e-05 23.8 6.9 0.047 14.0 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EPY53769.1 - 0.094 12.8 1.6 0.16 12.1 1.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EPY53769.1 - 1.1 9.6 4.8 1.9 8.9 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain SPC12 PF06645.8 EPY53771.1 - 3.9e-18 65.0 1.1 4.3e-18 64.8 0.8 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Nucleoside_tran PF01733.13 EPY53771.1 - 0.095 11.8 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Nucleoside transporter Sec62 PF03839.11 EPY53771.1 - 0.14 11.5 0.7 0.16 11.3 0.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Rpr2 PF04032.11 EPY53772.1 - 1.1e-21 76.4 7.0 1.5e-21 76.0 4.9 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PhnA_Zn_Ribbon PF08274.7 EPY53772.1 - 0.0029 17.3 0.0 0.0078 15.9 0.0 1.7 1 1 0 1 1 1 1 PhnA Zinc-Ribbon A2L_zn_ribbon PF08792.5 EPY53772.1 - 0.013 14.9 3.2 0.77 9.2 0.0 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain Mut7-C PF01927.11 EPY53772.1 - 0.017 15.0 3.5 0.023 14.6 2.5 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain WAC_Acf1_DNA_bd PF10537.4 EPY53772.1 - 0.1 12.8 0.2 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.24 EPY53772.1 - 0.56 9.9 4.4 1.3 8.8 3.0 1.6 1 0 0 1 1 1 0 PHD-finger SIR2 PF02146.12 EPY53772.1 - 0.98 9.1 4.2 1.4 8.6 2.7 1.4 1 1 0 1 1 1 0 Sir2 family FYVE PF01363.16 EPY53772.1 - 1.2 9.1 7.1 0.69 9.8 3.3 2.0 2 0 0 2 2 2 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 EPY53772.1 - 1.7 8.5 7.7 0.63 9.8 3.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EPY53772.1 - 1.8 8.2 4.7 1.9 8.1 0.6 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger RNA_POL_M_15KD PF02150.11 EPY53772.1 - 9 6.0 6.9 2.5e+02 1.4 4.8 2.6 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit RF-1 PF00472.15 EPY53773.1 - 5.1e-24 84.2 4.9 7.5e-24 83.7 3.4 1.2 1 0 0 1 1 1 1 RF-1 domain Histone PF00125.19 EPY53774.1 - 2.6e-31 107.5 0.3 3.5e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPY53774.1 - 0.0022 18.0 0.8 0.0062 16.5 0.6 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPY53774.1 - 0.0033 17.5 0.2 0.0051 16.9 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EPY53774.1 - 0.057 12.6 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Antimicrobial12 PF08107.6 EPY53774.1 - 0.069 12.7 0.1 3.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Pleurocidin family ARD PF03079.9 EPY53775.1 - 1.5e-48 164.6 0.1 1.8e-48 164.4 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EPY53775.1 - 3.2e-09 36.1 0.0 5.2e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EPY53775.1 - 1.1e-05 25.0 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.1 EPY53775.1 - 0.076 12.5 0.0 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Exo5 PF09810.4 EPY53777.1 - 1.6e-79 267.4 0.3 2.1e-79 267.0 0.2 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EPY53777.1 - 0.00047 19.6 0.0 0.0018 17.6 0.0 2.0 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EPY53777.1 - 0.049 13.5 0.2 4.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF83 INCENP_ARK-bind PF03941.10 EPY53778.1 - 1.9e-22 78.8 6.0 3.4e-22 78.0 2.9 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Pkinase PF00069.20 EPY53779.1 - 2.7e-10 39.8 0.1 8.3e-10 38.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53779.1 - 3e-05 23.2 0.0 5.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Auxin_repressed PF05564.7 EPY53779.1 - 0.026 15.1 0.3 0.12 12.9 0.1 2.1 2 0 0 2 2 2 0 Dormancy/auxin associated protein Peptidase_S24 PF00717.18 EPY53780.1 - 2.7e-07 30.1 0.1 7e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EPY53780.1 - 5.4e-05 22.7 0.0 0.0081 15.6 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Ank_4 PF13637.1 EPY53781.1 - 2.9e-11 43.5 6.0 0.00089 19.7 0.1 4.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPY53781.1 - 2.5e-10 40.5 1.2 0.00062 20.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPY53781.1 - 1e-07 31.9 4.0 1.3e-05 25.2 0.0 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPY53781.1 - 5.3e-07 29.2 3.4 0.011 15.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EPY53781.1 - 1.8e-05 24.3 3.6 0.0046 16.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat PspA_IM30 PF04012.7 EPY53781.1 - 0.0037 16.6 5.5 0.009 15.3 3.8 1.5 1 1 0 1 1 1 1 PspA/IM30 family EF-hand_7 PF13499.1 EPY53781.1 - 0.033 14.3 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair CENP-Q PF13094.1 EPY53781.1 - 0.15 12.0 9.8 0.26 11.3 5.6 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 EPY53781.1 - 0.22 11.3 10.3 1.2 8.9 0.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 EPY53781.1 - 4.7 4.9 10.0 7.2 4.3 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps52 PF04129.7 EPY53782.1 - 1.4e-129 432.8 10.0 1.6e-129 432.7 6.9 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family eIF-5a PF01287.15 EPY53783.1 - 1.1e-25 89.3 0.3 1.5e-25 88.8 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EPY53783.1 - 8.3e-05 22.1 1.0 8.3e-05 22.1 0.7 2.2 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EPY53783.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 EPY53784.1 - 1.3e-07 30.9 2.6 2.1e-07 30.2 1.8 1.3 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Spc24 PF08286.6 EPY53785.1 - 1e-28 99.3 5.5 1e-28 99.3 3.8 2.0 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 APG6 PF04111.7 EPY53785.1 - 0.011 14.8 10.4 0.014 14.4 7.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 EPY53785.1 - 0.016 15.0 3.6 0.022 14.5 2.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 EPY53785.1 - 0.087 10.6 9.1 0.1 10.4 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 EPY53785.1 - 0.13 11.8 10.6 0.21 11.2 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4613 PF15390.1 EPY53785.1 - 0.15 10.2 4.4 0.16 10.0 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Sec2p PF06428.6 EPY53785.1 - 0.24 11.2 15.8 0.17 11.7 6.1 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p AKNA PF12443.3 EPY53785.1 - 0.29 11.1 10.7 1.2 9.1 4.4 2.2 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF3373 PF11853.3 EPY53785.1 - 0.3 9.5 9.3 0.036 12.6 2.7 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3373) CemA PF03040.9 EPY53785.1 - 0.47 10.0 3.4 0.65 9.5 2.4 1.2 1 0 0 1 1 1 0 CemA family DUF3571 PF12095.3 EPY53785.1 - 0.77 10.0 11.4 0.13 12.4 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) RPW8 PF05659.6 EPY53785.1 - 1.2 8.6 7.1 4.9 6.6 4.9 1.9 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fib_alpha PF08702.5 EPY53785.1 - 1.2 9.2 10.3 2.2 8.4 7.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF919 PF06034.6 EPY53785.1 - 1.6 8.4 9.1 2.9 7.6 0.8 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) IncA PF04156.9 EPY53785.1 - 2.3 7.7 17.9 3.8 7.0 12.4 1.3 1 0 0 1 1 1 0 IncA protein DUF2203 PF09969.4 EPY53785.1 - 3.1 8.0 8.6 17 5.6 5.5 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Laminin_II PF06009.7 EPY53785.1 - 3.3 7.4 10.9 4.6 7.0 6.7 1.7 1 1 1 2 2 2 0 Laminin Domain II I_LWEQ PF01608.12 EPY53785.1 - 4 7.3 8.3 5.8 6.8 5.8 1.3 1 0 0 1 1 1 0 I/LWEQ domain FlxA PF14282.1 EPY53785.1 - 5.2 7.0 16.1 0.6 10.0 4.9 2.6 1 1 0 2 2 2 0 FlxA-like protein zf-ZPR1 PF03367.8 EPY53785.1 - 5.5 6.1 6.4 12 5.0 0.6 2.2 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DUF999 PF06198.6 EPY53786.1 - 2.4e-07 30.6 1.0 6.8e-07 29.1 0.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF999) DUF2207 PF09972.4 EPY53786.1 - 0.09 11.3 0.5 0.12 10.9 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) B-block_TFIIIC PF04182.7 EPY53787.1 - 5.4e-18 64.6 0.1 2.1e-17 62.7 0.1 2.1 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Myb_DNA-bind_6 PF13921.1 EPY53787.1 - 0.0016 18.5 0.0 0.0077 16.3 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPY53787.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Corona_5a PF06336.6 EPY53789.1 - 0.26 11.1 2.2 0.73 9.7 1.5 1.7 1 0 0 1 1 1 0 Coronavirus 5a protein 5-FTHF_cyc-lig PF01812.15 EPY53790.1 - 1.2e-37 129.5 0.0 1.3e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family CoA_binding PF02629.14 EPY53791.1 - 6.6e-16 58.5 0.0 1.7e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Citrate_synt PF00285.16 EPY53791.1 - 1.7e-15 56.6 0.0 1.3e-14 53.7 0.0 2.1 1 1 0 1 1 1 1 Citrate synthase Ligase_CoA PF00549.14 EPY53791.1 - 8e-14 51.5 0.0 1.4e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EPY53791.1 - 3.2e-06 26.7 0.0 5.4e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain F-box-like PF12937.2 EPY53792.1 - 2.7e-12 46.1 1.5 5e-12 45.3 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPY53792.1 - 3.7e-07 29.6 3.1 8.5e-07 28.4 2.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EPY53792.1 - 0.008 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain UIM PF02809.15 EPY53792.1 - 0.61 9.8 19.6 0.1 12.2 0.9 2.9 3 0 0 3 3 3 0 Ubiquitin interaction motif WD40 PF00400.27 EPY53792.1 - 6.8 6.7 6.7 1.3 9.0 0.7 2.9 4 1 0 4 4 4 0 WD domain, G-beta repeat RIO1 PF01163.17 EPY53793.1 - 4.2e-52 176.2 0.0 4.2e-52 176.2 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 EPY53793.1 - 4.5e-32 109.9 0.1 8.6e-32 109.0 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EPY53793.1 - 2.3e-15 57.0 0.8 2.2e-07 30.8 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EPY53793.1 - 3.3e-05 23.1 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EPY53793.1 - 4.4e-05 22.6 0.0 0.0036 16.3 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPY53793.1 - 0.053 12.4 0.5 1.1 8.1 0.0 2.4 3 0 0 3 3 3 0 Kinase-like DNA_mis_repair PF01119.14 EPY53794.1 - 6.1e-25 87.0 0.2 1.1e-24 86.1 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPY53794.1 - 1e-13 51.0 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPY53794.1 - 6.4e-11 41.9 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Arm PF00514.18 EPY53795.1 - 0.00047 19.8 1.0 0.0076 16.0 0.1 3.6 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPY53795.1 - 0.024 14.9 1.5 2.1 8.7 0.3 4.1 3 1 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.1 EPY53795.1 - 0.19 12.2 0.2 0.19 12.2 0.1 3.8 5 0 0 5 5 5 0 HEAT-like repeat ARID PF01388.16 EPY53796.1 - 2.9e-13 49.4 0.1 9.4e-13 47.8 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain UPF0086 PF01868.11 EPY53797.1 - 4e-14 52.0 0.0 8e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Sld5 PF05916.6 EPY53798.1 - 3.8e-06 27.1 0.2 8.8e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 GINS complex protein DUF692 PF05114.8 EPY53798.1 - 0.086 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF692) DcpS_C PF11969.3 EPY53799.1 - 2.3e-28 98.7 1.0 4.2e-28 97.8 0.7 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EPY53799.1 - 6.3e-28 97.3 0.8 1.6e-27 96.0 0.6 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Calreticulin PF00262.13 EPY53800.1 - 2e-21 76.0 0.1 8.5e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 Calreticulin family Abhydrolase_6 PF12697.2 EPY53802.1 - 6.7e-24 85.0 0.0 8.5e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY53802.1 - 3e-12 46.5 0.0 3.8e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPY53802.1 - 9.1e-11 41.7 0.0 2.3e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EPY53802.1 - 0.00012 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF915 PF06028.6 EPY53802.1 - 0.00014 21.0 0.1 0.015 14.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 EPY53802.1 - 0.0014 18.8 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EPY53802.1 - 0.0052 16.3 0.1 0.0076 15.8 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF1057 PF06342.7 EPY53802.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.8 EPY53802.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EPY53802.1 - 0.025 14.1 0.1 0.041 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.8 EPY53802.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.2 EPY53802.1 - 0.06 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF3530 PF12048.3 EPY53802.1 - 0.061 12.2 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF2305 PF10230.4 EPY53802.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Aconitase PF00330.15 EPY53804.1 - 5.1e-162 539.5 0.0 1.3e-161 538.1 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPY53804.1 - 5.9e-39 133.1 0.0 1.4e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Ribosomal_L21p PF00829.16 EPY53804.1 - 1.6e-09 37.7 0.1 3.2e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF521 PF04412.8 EPY53804.1 - 0.027 13.0 0.0 0.046 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Transp_cyt_pur PF02133.10 EPY53805.1 - 9e-163 541.9 41.0 1.1e-162 541.6 28.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosom_S12_S23 PF00164.20 EPY53807.1 - 7.5e-40 135.1 0.5 8.9e-40 134.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF336 PF03928.9 EPY53808.1 - 4.4e-22 78.2 0.0 5.8e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) AMP-binding PF00501.23 EPY53810.1 - 5e-79 265.6 0.0 7.5e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Rhomboid PF01694.17 EPY53811.1 - 1.4e-18 67.3 10.8 1.1e-12 48.2 1.1 2.5 3 0 0 3 3 3 2 Rhomboid family DUF457 PF04307.9 EPY53811.1 - 5.9 6.2 8.6 3.1 7.1 1.5 2.6 2 1 1 3 3 3 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) zf-H2C2_2 PF13465.1 EPY53812.1 - 3.5e-08 33.3 10.4 5.5e-07 29.5 1.6 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPY53812.1 - 4.5e-07 29.8 10.1 0.0062 16.8 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPY53812.1 - 5.9e-06 26.2 11.1 0.0036 17.5 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EPY53812.1 - 0.07 13.2 2.1 0.15 12.2 1.5 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EPY53812.1 - 0.098 12.5 3.1 8 6.5 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.4 EPY53812.1 - 0.14 11.6 0.5 0.2 11.0 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EPY53812.1 - 0.58 10.3 5.1 0.89 9.7 1.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding QCR10 PF09796.4 EPY53814.1 - 3.8e-22 77.7 0.8 4.8e-22 77.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) zf-RING_2 PF13639.1 EPY53815.1 - 6e-15 54.8 8.8 9.7e-15 54.1 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPY53815.1 - 1e-10 41.5 2.1 1.9e-10 40.7 1.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPY53815.1 - 3.9e-07 29.6 6.6 6.2e-07 29.0 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPY53815.1 - 8.9e-07 28.6 1.1 1.6e-06 27.8 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EPY53815.1 - 9.1e-07 28.4 6.8 1.5e-06 27.7 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPY53815.1 - 1e-06 28.6 7.7 1.6e-06 27.9 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY53815.1 - 3.8e-05 23.2 4.5 6.3e-05 22.5 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EPY53815.1 - 0.017 14.6 2.0 0.033 13.7 1.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.2 EPY53815.1 - 0.057 13.4 8.4 0.1 12.6 5.8 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EPY53815.1 - 0.17 11.9 6.5 0.29 11.1 4.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EPY53815.1 - 0.59 9.7 2.4 1.4 8.5 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPY53815.1 - 1.5 8.6 4.3 4 7.2 3.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPY53815.1 - 1.9 8.1 6.2 3.5 7.2 4.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPY53815.1 - 3.2 7.7 6.1 11 5.9 4.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SMC_N PF02463.14 EPY53816.1 - 4.8e-71 238.4 0.0 1e-70 237.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPY53816.1 - 8.9e-18 64.3 2.8 1.4e-17 63.7 0.1 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPY53816.1 - 4.4e-12 46.5 2.6 1.1e-06 28.8 0.1 5.5 3 2 1 5 5 5 2 AAA domain AAA_29 PF13555.1 EPY53816.1 - 3.5e-05 23.2 0.0 7.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mnd1 PF03962.10 EPY53816.1 - 0.0024 17.5 14.3 0.0024 17.5 9.9 7.7 3 2 4 7 7 7 2 Mnd1 family ABC_tran PF00005.22 EPY53816.1 - 0.13 12.6 0.0 0.13 12.6 0.0 5.8 4 3 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EPY53816.1 - 0.22 10.6 37.4 0.15 11.2 0.7 5.7 3 2 4 7 7 7 0 Reovirus sigma C capsid protein FUSC PF04632.7 EPY53816.1 - 2.5 6.4 17.0 0.17 10.2 5.2 2.4 2 1 1 3 3 3 0 Fusaric acid resistance protein family SAM_decarbox PF01536.11 EPY53817.1 - 4.9e-92 308.1 0.4 5.8e-92 307.8 0.3 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Metallophos PF00149.23 EPY53818.1 - 1.6e-44 151.7 1.8 2.4e-44 151.1 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 60KD_IMP PF02096.15 EPY53819.1 - 1.8e-36 125.7 4.5 3e-36 124.9 3.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Hid1 PF12722.2 EPY53820.1 - 1.4e-39 135.5 31.2 1.9e-39 135.1 21.6 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EPY53820.1 - 2.9e-10 38.9 7.2 9.8e-09 33.8 5.0 2.2 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF2933 PF11666.3 EPY53820.1 - 0.3 10.6 0.0 0.3 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) PLU-1 PF08429.6 EPY53821.1 - 2.3e-71 240.4 4.6 3.5e-71 239.8 3.2 1.3 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 EPY53821.1 - 4.8e-20 71.9 0.2 1.5e-19 70.3 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EPY53821.1 - 2.2e-16 59.2 25.2 6.8e-12 44.8 4.3 3.1 3 0 0 3 3 3 2 PHD-finger ARID PF01388.16 EPY53821.1 - 8.4e-11 41.5 0.2 4e-10 39.4 0.2 2.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 EPY53821.1 - 1.8e-06 27.9 1.9 1.8e-06 27.9 1.3 2.8 2 0 0 2 2 2 1 C5HC2 zinc finger FIBP PF05427.6 EPY53821.1 - 0.00042 19.6 0.1 0.00076 18.8 0.1 1.3 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) JmjN PF02375.12 EPY53821.1 - 0.00057 19.3 0.0 0.0014 18.0 0.0 1.8 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.1 EPY53821.1 - 0.00058 19.1 15.9 0.0011 18.2 1.0 3.3 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EPY53821.1 - 0.0013 18.3 2.9 0.0013 18.3 2.0 4.0 4 1 1 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EPY53821.1 - 0.0061 16.2 20.3 0.009 15.7 0.3 3.5 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EPY53821.1 - 0.015 14.6 10.6 0.04 13.2 0.2 3.0 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PolC_DP2 PF03833.8 EPY53821.1 - 0.077 10.6 1.5 0.15 9.6 1.1 1.4 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-AD PF07776.10 EPY53821.1 - 0.22 11.5 6.4 3 7.9 1.0 4.6 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) zf-RING_2 PF13639.1 EPY53821.1 - 3.5 7.5 21.9 0.54 10.1 4.3 3.4 3 0 0 3 3 3 0 Ring finger domain Ribosomal_L27 PF01016.14 EPY53822.1 - 1.8e-31 107.7 2.4 2.3e-31 107.4 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein MOR2-PAG1_N PF14222.1 EPY53823.1 - 5.8e-97 325.6 21.4 3.2e-93 313.3 7.3 2.9 2 1 1 3 3 3 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EPY53823.1 - 3.1e-66 223.8 3.6 7.7e-66 222.5 2.5 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EPY53823.1 - 1.7e-24 85.5 4.9 2.8e-14 51.7 0.1 3.5 3 1 0 3 3 3 3 Cell morphogenesis central region PC_rep PF01851.17 EPY53824.1 - 4.6e-22 76.9 23.9 1.3e-05 25.1 0.1 9.0 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPY53824.1 - 0.00077 19.6 2.4 1.8 8.8 0.1 3.9 4 1 0 4 4 4 2 HEAT repeats GCV_H PF01597.14 EPY53826.1 - 7.8e-41 138.5 0.2 1.1e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EPY53826.1 - 0.0015 18.0 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 EPY53826.1 - 0.0088 15.7 0.2 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Glyco_transf_15 PF01793.11 EPY53827.1 - 3.6e-134 446.9 16.5 4.3e-134 446.6 11.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Voltage_CLC PF00654.15 EPY53828.1 - 6.1e-90 301.7 26.1 1.7e-89 300.3 17.9 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EPY53828.1 - 2.6e-07 30.2 0.0 0.002 17.8 0.0 2.7 2 1 0 2 2 2 2 CBS domain Na_K-ATPase PF00287.13 EPY53828.1 - 5.9 5.5 9.2 2.1 7.0 0.9 2.2 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain KilA-N PF04383.8 EPY53829.1 - 0.029 13.9 0.6 1.1 8.9 0.0 2.7 2 1 0 2 2 2 0 KilA-N domain UvdE PF03851.9 EPY53830.1 - 3.2e-107 357.6 0.0 4.5e-107 357.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE LCM PF04072.9 EPY53831.1 - 5.6e-24 84.7 0.0 9.1e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_6 PF13964.1 EPY53831.1 - 0.00016 21.7 5.8 0.084 13.0 0.0 4.3 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EPY53831.1 - 0.0013 18.4 8.8 0.23 11.2 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EPY53831.1 - 0.063 13.4 3.0 18 5.6 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain KcnmB2_inactiv PF09303.5 EPY53831.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain tRNA_int_endo PF01974.12 EPY53832.1 - 1.5e-15 56.7 0.0 3.6e-15 55.5 0.0 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain ProRS-C_1 PF09180.6 EPY53833.1 - 3.6e-23 81.2 0.6 9.3e-23 79.9 0.4 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EPY53833.1 - 2.7e-21 75.9 0.0 1.2e-20 73.7 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPY53833.1 - 3.1e-17 62.3 0.0 6.9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 EPY53833.1 - 7.9e-16 58.0 0.8 1.6e-15 57.0 0.6 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain RCR PF12273.3 EPY53834.1 - 2.5e-11 44.2 13.9 1.3e-10 41.8 9.6 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red YwiC PF14256.1 EPY53834.1 - 0.018 15.1 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 YwiC-like protein DUF1514 PF07438.6 EPY53834.1 - 0.082 12.8 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) DUF3328 PF11807.3 EPY53834.1 - 0.085 12.5 1.7 0.13 11.9 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Shisa PF13908.1 EPY53834.1 - 2.4 8.3 6.1 4.4 7.4 4.2 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2406 PF10295.4 EPY53836.1 - 1.3e-17 64.0 0.4 2.8e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Guanylate_cyc PF00211.15 EPY53837.1 - 1.5e-40 138.5 0.0 2.4e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_8 PF13855.1 EPY53837.1 - 1.9e-40 136.4 61.8 3.9e-08 32.9 1.9 9.8 5 3 6 11 11 11 11 Leucine rich repeat LRR_4 PF12799.2 EPY53837.1 - 3.2e-38 128.7 69.4 6e-09 35.3 0.3 12.7 7 4 4 12 12 12 10 Leucine Rich repeats (2 copies) PP2C PF00481.16 EPY53837.1 - 2.9e-35 121.9 0.1 9.8e-35 120.1 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EPY53837.1 - 1.8e-18 63.6 74.8 0.075 13.1 0.1 19.5 20 2 1 21 21 21 8 Leucine Rich Repeat LRR_7 PF13504.1 EPY53837.1 - 3.2e-11 41.5 40.0 1 9.8 0.0 15.8 18 0 0 18 18 18 2 Leucine rich repeat RA PF00788.18 EPY53837.1 - 4.2e-09 36.7 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 EPY53837.1 - 1.2e-05 24.8 63.4 2.7 8.3 0.1 16.8 17 1 0 17 17 17 4 Leucine Rich repeat GTP_EFTU PF00009.22 EPY53838.1 - 2.7e-42 144.3 0.1 7.8e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EPY53838.1 - 5.8e-14 51.9 2.0 1.6e-13 50.5 1.4 1.8 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 EPY53838.1 - 7e-06 26.0 0.0 1.9e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 EPY53838.1 - 0.00012 22.1 0.0 0.00038 20.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.1 EPY53838.1 - 0.0002 20.9 0.0 0.00072 19.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPY53838.1 - 0.00056 19.8 0.0 0.0087 16.0 0.0 2.8 2 2 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPY53838.1 - 0.013 15.9 1.7 0.04 14.4 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EPY53838.1 - 0.014 14.1 1.9 0.024 13.3 1.3 1.4 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 EPY53839.1 - 7e-59 198.0 0.0 1.1e-28 100.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPY53839.1 - 2.2e-47 161.8 50.2 6.2e-27 94.7 16.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_17 PF13207.1 EPY53839.1 - 1.3e-12 48.6 0.0 3.9e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EPY53839.1 - 1.4e-12 48.1 3.2 0.012 15.5 0.0 5.3 4 1 1 5 5 4 3 AAA domain SMC_N PF02463.14 EPY53839.1 - 8.4e-10 38.2 8.3 7.1e-06 25.4 0.1 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPY53839.1 - 6.3e-09 35.2 1.0 0.003 17.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EPY53839.1 - 9.6e-08 32.3 0.0 0.016 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPY53839.1 - 2.1e-07 31.1 0.4 0.011 15.9 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPY53839.1 - 2.8e-06 26.9 0.4 0.065 12.6 0.0 3.6 4 0 0 4 4 3 2 AAA-like domain AAA_16 PF13191.1 EPY53839.1 - 3.5e-06 27.1 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EPY53839.1 - 2e-05 24.4 0.0 0.11 12.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.12 EPY53839.1 - 0.00011 22.1 0.1 0.095 12.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_14 PF13173.1 EPY53839.1 - 0.0002 21.2 0.1 1.3 8.9 0.0 3.7 3 1 1 4 4 3 1 AAA domain DUF258 PF03193.11 EPY53839.1 - 0.00022 20.4 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EPY53839.1 - 0.00024 19.8 1.8 0.26 9.8 0.0 4.4 5 0 0 5 5 5 1 Predicted ATPase of the ABC class AAA_28 PF13521.1 EPY53839.1 - 0.00058 19.8 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPY53839.1 - 0.00091 18.9 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.11 EPY53839.1 - 0.0013 18.2 0.0 0.19 11.1 0.0 2.5 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_5 PF07728.9 EPY53839.1 - 0.0014 18.3 0.0 0.87 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPY53839.1 - 0.0017 18.4 0.0 1.5 9.0 0.0 3.0 2 0 0 2 2 2 1 RNA helicase PRK PF00485.13 EPY53839.1 - 0.0019 17.8 0.0 0.84 9.1 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.1 EPY53839.1 - 0.0029 17.0 2.4 0.62 9.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPY53839.1 - 0.0037 16.7 0.1 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 EPY53839.1 - 0.0039 17.2 0.0 8.2 6.4 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.1 EPY53839.1 - 0.0047 16.5 0.1 0.51 9.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EPY53839.1 - 0.0049 16.7 0.5 0.67 9.9 0.1 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EPY53839.1 - 0.0084 16.4 3.0 1.2 9.4 0.1 2.9 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EPY53839.1 - 0.013 14.6 0.0 0.76 8.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EPY53839.1 - 0.021 14.5 0.0 5.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 EPY53839.1 - 0.025 14.3 0.2 2.7 7.6 0.0 3.1 3 0 0 3 3 3 0 NTPase ATP_bind_1 PF03029.12 EPY53839.1 - 0.028 13.9 0.4 5.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.15 EPY53839.1 - 0.03 13.9 0.1 7.9 6.1 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase DUF3987 PF13148.1 EPY53839.1 - 0.033 12.7 0.0 4.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) T2SE PF00437.15 EPY53839.1 - 0.034 13.0 0.0 5.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 EPY53839.1 - 0.035 13.5 1.8 16 4.8 0.0 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein NB-ARC PF00931.17 EPY53839.1 - 0.047 12.5 1.3 13 4.5 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain Miro PF08477.8 EPY53839.1 - 0.06 13.8 0.0 3.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DEAD PF00270.24 EPY53839.1 - 0.064 12.7 1.0 0.62 9.5 0.1 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activat PF00158.21 EPY53839.1 - 0.068 12.6 0.0 5.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 EPY53839.1 - 0.087 12.4 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA PF00004.24 EPY53839.1 - 0.12 12.5 0.1 30 4.8 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CoaE PF01121.15 EPY53839.1 - 0.14 11.5 0.2 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase KaiC PF06745.8 EPY53839.1 - 0.15 11.1 0.9 5.2 6.1 0.1 2.6 2 0 0 2 2 2 0 KaiC CbiA PF01656.18 EPY53839.1 - 0.24 10.8 0.8 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EPY53839.1 - 0.36 10.4 2.8 23 4.5 0.0 3.6 4 0 0 4 4 3 0 NACHT domain MMR_HSR1 PF01926.18 EPY53841.1 - 5.4e-15 55.3 0.0 1.1e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPY53841.1 - 9.3e-09 34.7 0.0 8.3e-08 31.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 EPY53841.1 - 0.00029 20.0 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EPY53841.1 - 0.00081 18.3 0.1 0.0028 16.5 0.0 1.7 1 1 1 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EPY53841.1 - 0.001 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPY53841.1 - 0.044 13.7 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 EPY53841.1 - 0.045 13.5 0.9 0.3 10.8 0.0 2.5 2 1 1 3 3 3 0 Dynamin family KH_4 PF13083.1 EPY53842.1 - 0.019 14.6 0.1 0.05 13.2 0.1 1.7 1 0 0 1 1 1 0 KH domain Pfg27 PF09216.5 EPY53842.1 - 0.044 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Pfg27 BTB PF00651.26 EPY53843.1 - 4.7e-05 23.3 0.1 0.00022 21.2 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain tRNA-synt_1d PF00750.14 EPY53845.1 - 1.1e-85 287.5 7.5 2.8e-85 286.2 5.2 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EPY53845.1 - 5.2e-29 100.6 0.9 5.8e-28 97.2 0.1 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EPY53845.1 - 0.00063 20.2 0.1 0.0028 18.1 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Usp PF00582.21 EPY53847.1 - 1.4e-19 70.6 0.0 2e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Myc_target_1 PF15179.1 EPY53847.1 - 0.028 14.0 1.9 0.061 12.9 1.2 1.6 1 1 0 1 1 1 0 Myc target protein 1 LRR_4 PF12799.2 EPY53848.1 - 2e-12 46.3 28.0 0.0046 16.5 0.0 8.9 2 2 7 9 9 9 6 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EPY53848.1 - 2.1e-09 36.9 1.0 7.7e-09 35.1 0.7 2.0 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EPY53848.1 - 8.5e-09 34.2 34.7 2 8.7 0.9 13.1 10 4 1 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.1 EPY53848.1 - 4.1e-06 26.4 33.6 0.0092 15.7 2.0 7.3 2 1 7 9 9 9 5 Leucine rich repeat LRR_6 PF13516.1 EPY53848.1 - 9.5e-05 22.0 40.1 5.5 7.3 0.3 12.5 13 1 0 13 13 13 2 Leucine Rich repeat STAS PF01740.16 EPY53848.1 - 0.027 13.8 0.2 0.89 8.9 0.0 2.5 2 0 0 2 2 2 0 STAS domain PRANC PF09372.5 EPY53848.1 - 0.1 12.5 4.0 0.11 12.4 0.2 3.0 3 0 0 3 3 3 0 PRANC domain Ste50p-SAM PF09235.5 EPY53848.1 - 0.2 11.7 7.8 7.4 6.6 0.5 5.0 4 0 0 4 4 4 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 EPY53848.1 - 1.5 9.3 39.8 7.2 7.2 0.0 11.3 13 1 0 13 13 13 0 Leucine rich repeat DUF3535 PF12054.3 EPY53849.1 - 8.2e-116 387.2 0.1 3.5e-115 385.1 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EPY53849.1 - 3e-72 242.9 1.1 1.1e-71 241.0 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.17 EPY53849.1 - 6.3e-18 63.1 13.2 0.0083 16.1 0.1 9.5 9 0 0 9 9 9 5 HEAT repeat Helicase_C PF00271.26 EPY53849.1 - 6.6e-13 48.3 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EPY53849.1 - 6.5e-11 42.3 3.1 0.012 15.8 0.0 6.7 4 3 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EPY53849.1 - 9.5e-07 29.1 11.3 0.77 10.3 0.0 8.1 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPY53849.1 - 3.4e-06 27.3 0.1 0.22 11.9 0.0 4.3 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EPY53849.1 - 0.033 14.0 0.2 5.4 7.0 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat GED PF02212.13 EPY53849.1 - 0.039 13.8 2.5 1.2 9.1 0.3 4.0 4 0 0 4 4 4 0 Dynamin GTPase effector domain DUF3385 PF11865.3 EPY53849.1 - 0.055 13.3 1.6 0.41 10.5 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) Pkinase PF00069.20 EPY53850.1 - 3.7e-40 137.7 0.0 6.5e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53850.1 - 1.4e-28 99.7 0.0 2.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY53850.1 - 0.0012 18.6 0.0 0.023 14.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY53850.1 - 0.025 13.5 0.0 0.087 11.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Pal1 PF08316.6 EPY53851.1 - 4.8e-14 52.9 0.0 1.3e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 Pal1 cell morphology protein LRS4 PF10422.4 EPY53852.1 - 3.1e-14 52.9 33.2 2.1e-13 50.2 23.0 2.3 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 Tropomyosin PF00261.15 EPY53852.1 - 0.011 14.8 15.7 0.016 14.3 0.8 2.4 2 0 0 2 2 2 0 Tropomyosin DUF4200 PF13863.1 EPY53852.1 - 0.023 14.6 16.7 0.13 12.1 1.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF4407 PF14362.1 EPY53852.1 - 0.089 11.7 4.9 0.22 10.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.6 EPY53852.1 - 0.22 11.9 9.9 0.82 10.1 0.7 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Reo_sigmaC PF04582.7 EPY53852.1 - 0.32 10.1 15.1 2.8 7.0 1.9 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EPY53852.1 - 1.9 8.2 23.4 0.19 11.4 6.3 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.1 EPY53852.1 - 2 8.5 9.3 7 6.8 1.6 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) ATG16 PF08614.6 EPY53852.1 - 3.7 7.3 23.8 6.3 6.5 6.8 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EPY53852.1 - 3.9 7.5 14.9 5.4 7.1 3.1 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ACCA PF03255.9 EPY53852.1 - 4.8 6.7 7.1 19 4.7 0.8 2.7 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_DNA_bd PF12329.3 EPY53852.1 - 6.2 6.7 24.4 1 9.2 4.8 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EPY53852.1 - 8.2 5.9 22.2 1.7 8.2 5.3 2.6 1 1 1 2 2 2 0 IncA protein TMCO5 PF14992.1 EPY53852.1 - 9.2 5.3 19.7 5.5 6.0 6.2 2.4 1 1 2 3 3 3 0 TMCO5 family ThiF PF00899.16 EPY53853.1 - 3.8e-28 98.0 0.0 8.8e-28 96.8 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EPY53853.1 - 0.0045 17.0 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UCH PF00443.24 EPY53854.1 - 4.5e-43 147.2 1.2 4.6e-43 147.2 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPY53854.1 - 5.7e-26 90.4 20.0 2.2e-20 72.5 3.2 3.7 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EPY53854.1 - 1.8e-25 88.0 2.7 9e-13 47.6 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EPY53854.1 - 8.4e-17 61.5 4.6 2.6e-15 56.6 3.2 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HBS1_N PF08938.5 EPY53854.1 - 0.023 14.7 0.0 0.075 13.1 0.0 1.9 1 0 0 1 1 1 0 HBS1 N-terminus CUE PF02845.11 EPY53854.1 - 0.049 13.1 1.4 1 8.8 0.0 3.2 3 0 0 3 3 3 0 CUE domain PRP1_N PF06424.7 EPY53856.1 - 3.1e-47 160.2 2.6 7.2e-47 159.0 1.8 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EPY53856.1 - 4.3e-25 85.9 10.6 0.0011 19.4 0.0 13.0 6 4 8 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPY53856.1 - 8.4e-19 67.6 4.7 0.013 15.8 0.0 8.2 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPY53856.1 - 5.1e-12 46.1 5.4 0.038 14.6 0.0 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPY53856.1 - 6.8e-11 41.2 4.7 0.24 11.4 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPY53856.1 - 1e-10 41.1 4.7 0.029 13.9 0.0 6.5 6 2 1 7 7 7 2 TPR repeat TPR_17 PF13431.1 EPY53856.1 - 5.8e-09 35.4 2.3 0.36 11.1 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPY53856.1 - 4.5e-08 32.3 0.1 0.49 10.0 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 EPY53856.1 - 1.8e-05 24.6 5.8 0.013 15.2 0.0 4.7 3 1 3 6 6 6 2 Suppressor of forked protein (Suf) TPR_8 PF13181.1 EPY53856.1 - 0.0002 20.8 2.6 80 3.3 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY53856.1 - 0.0006 20.0 2.8 4.5 7.9 0.0 5.8 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPY53856.1 - 0.0033 17.3 1.9 25 4.8 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EPY53856.1 - 0.018 13.7 5.7 5.4 5.6 0.0 4.4 5 0 0 5 5 5 0 NMDA receptor-regulated protein 1 NRDE-2 PF08424.5 EPY53856.1 - 0.058 12.2 0.0 0.058 12.2 0.0 6.0 3 2 3 6 6 6 0 NRDE-2, necessary for RNA interference Ofd1_CTDD PF10637.4 EPY53857.1 - 1.8e-78 263.3 0.0 2.8e-74 249.6 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EPY53857.1 - 1.6e-13 51.0 0.0 3.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EnY2 PF10163.4 EPY53858.1 - 2.7e-19 68.8 0.1 3.2e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 FHA PF00498.21 EPY53859.1 - 3.1e-10 40.0 0.0 8.3e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EPY53859.1 - 0.069 13.3 0.3 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain P53_TAD PF08563.6 EPY53859.1 - 1.8 7.7 4.3 0.34 10.0 0.1 2.0 2 0 0 2 2 2 0 P53 transactivation motif UPF0300 PF08594.5 EPY53860.1 - 4e-62 208.9 2.0 4e-62 208.9 1.4 1.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0300) EmrE PF13536.1 EPY53861.1 - 1.9 8.7 9.4 3.9 7.7 6.5 1.6 1 1 0 1 1 1 0 Multidrug resistance efflux transporter WD40 PF00400.27 EPY53864.1 - 1.5e-37 126.1 14.4 3.3e-10 39.4 0.1 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 EPY53864.1 - 0.02 13.0 0.0 0.045 11.9 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PIP5K PF01504.13 EPY53865.1 - 9.9e-62 208.2 0.6 2.4e-61 207.0 0.4 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EPY53865.1 - 1e-22 80.4 0.0 1.8e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EPY53865.1 - 3.4e-16 58.9 9.6 3.4e-16 58.9 6.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger Ric8 PF10165.4 EPY53866.1 - 2.8e-51 174.7 0.0 3.4e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Mitofilin PF09731.4 EPY53867.1 - 6.9e-75 252.8 32.1 1.6e-60 205.3 20.3 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein MFS_1 PF07690.11 EPY53868.1 - 7.1e-46 156.5 38.5 7.1e-46 156.5 26.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY53868.1 - 2.3e-20 72.6 28.5 1.3e-14 53.6 5.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Cas_APE2256 PF09651.5 EPY53868.1 - 0.0038 16.9 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_APE2256) Transgly_assoc PF04226.8 EPY53868.1 - 0.035 14.1 1.5 0.035 14.1 1.0 4.3 4 0 0 4 4 4 0 Transglycosylase associated protein Polysacc_synt_4 PF04669.8 EPY53869.1 - 2.9e-23 82.2 1.3 1.7e-22 79.7 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis XPG_N PF00752.12 EPY53870.1 - 7e-38 128.9 0.0 1.9e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPY53870.1 - 6.8e-24 83.7 0.0 3e-23 81.7 0.0 2.2 1 0 0 1 1 1 1 XPG I-region DUF2229 PF09989.4 EPY53870.1 - 0.69 9.3 3.9 0.27 10.6 0.3 2.0 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Sad1_UNC PF07738.8 EPY53871.1 - 3.3e-36 124.0 1.6 5.4e-36 123.3 0.1 2.1 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal GPCR_chapero_1 PF11904.3 EPY53871.1 - 0.0027 16.9 1.1 0.0027 16.9 0.8 1.9 2 1 0 2 2 2 1 GPCR-chaperone Peptidase_M24 PF00557.19 EPY53872.1 - 2.9e-43 147.8 0.0 3.6e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EPY53872.1 - 0.00052 19.8 6.0 0.00052 19.8 4.1 1.8 2 0 0 2 2 2 1 MYND finger DnaJ-X PF14308.1 EPY53873.1 - 8.4e-57 191.7 2.9 8.4e-57 191.7 2.0 1.7 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EPY53873.1 - 1.4e-26 92.0 0.6 2.8e-26 91.0 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain Sel1 PF08238.7 EPY53874.1 - 1.5e-10 41.3 13.9 0.00092 19.7 0.6 4.1 5 0 0 5 5 5 3 Sel1 repeat dsrm PF00035.20 EPY53874.1 - 0.014 15.9 0.0 3 8.4 0.0 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif TPR_19 PF14559.1 EPY53874.1 - 0.068 13.5 0.0 8.9 6.7 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SYF2 PF08231.7 EPY53875.1 - 3.3e-45 153.9 26.1 3.3e-45 153.9 18.1 2.0 2 0 0 2 2 2 1 SYF2 splicing factor DUF3209 PF11483.3 EPY53875.1 - 0.037 14.3 3.8 0.073 13.4 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) LSM PF01423.17 EPY53876.1 - 3.4e-21 74.5 0.0 3.9e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPY53876.1 - 0.00044 20.1 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain TRAM_LAG1_CLN8 PF03798.11 EPY53877.1 - 3.3e-35 121.4 32.5 3.3e-35 121.4 22.5 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPY53877.1 - 7.8e-18 63.7 0.1 7.8e-18 63.7 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein HMGL-like PF00682.14 EPY53878.1 - 1e-60 205.3 0.0 1.5e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EPY53878.1 - 7e-27 93.8 0.0 1.2e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain GST_N_2 PF13409.1 EPY53878.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_L23eN PF03939.8 EPY53879.1 - 7.8e-21 73.8 7.3 7.8e-21 73.8 5.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EPY53879.1 - 1.2e-16 60.4 2.1 2.6e-16 59.3 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Lectin_leg-like PF03388.8 EPY53880.1 - 8.1e-41 139.6 0.1 1.3e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Baculo_PEP_C PF04513.7 EPY53880.1 - 0.024 14.4 3.0 0.066 13.0 0.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EPY53880.1 - 0.06 12.9 2.5 0.093 12.2 1.7 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EPY53880.1 - 0.11 12.3 1.6 0.17 11.7 0.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.20 EPY53881.1 - 3e-78 262.5 0.1 5.9e-78 261.6 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53881.1 - 1e-37 129.6 0.1 3.3e-36 124.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EPY53881.1 - 9.5e-19 66.5 0.1 1.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EPY53881.1 - 2.4e-07 30.0 0.0 2e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPY53881.1 - 3.4e-07 29.5 0.1 1.4e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPY53881.1 - 0.00044 20.0 0.1 0.086 12.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EPY53881.1 - 0.0009 18.6 0.5 0.0023 17.2 0.4 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EPY53881.1 - 0.021 14.1 1.6 0.084 12.2 1.1 1.9 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DEAD PF00270.24 EPY53882.1 - 1.4e-43 148.3 0.3 3.5e-43 147.0 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY53882.1 - 1.5e-25 88.8 0.1 1.9e-24 85.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPY53882.1 - 1.3e-07 31.5 2.5 1.5e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPY53882.1 - 9.4e-06 24.6 0.0 1.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EPY53882.1 - 0.0033 15.8 0.2 2.1 6.6 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EPY53882.1 - 0.008 16.3 0.5 0.029 14.5 0.4 2.1 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EPY53882.1 - 0.014 15.0 0.0 0.037 13.6 0.0 1.8 1 0 0 1 1 1 0 Helicase Helicase_C_2 PF13307.1 EPY53882.1 - 0.069 13.0 0.0 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain Ribosomal_L33 PF00471.15 EPY53883.1 - 2.6e-08 33.9 0.0 3.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 TRI12 PF06609.8 EPY53884.1 - 2.6e-18 65.5 26.1 3.5e-18 65.1 18.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPY53884.1 - 5.1e-17 61.6 49.9 3.5e-11 42.4 21.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily VPS9 PF02204.13 EPY53885.1 - 3.4e-30 104.1 0.1 7.9e-30 102.9 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EPY53885.1 - 6.9e-08 31.8 0.1 1.3e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 CUE domain Filo_VP35 PF02097.10 EPY53885.1 - 0.046 12.9 0.1 0.046 12.9 0.0 1.9 2 0 0 2 2 2 0 Filoviridae VP35 DUF908 PF06012.7 EPY53885.1 - 0.13 11.5 4.5 0.29 10.3 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Asn_synthase PF00733.16 EPY53886.1 - 9.5e-51 172.7 0.0 1.2e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPY53886.1 - 2.5e-13 49.8 0.0 5.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EPY53886.1 - 9.6e-10 38.5 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EPY53886.1 - 0.03 13.5 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein LIM PF00412.17 EPY53887.1 - 4e-25 87.6 35.1 1.3e-11 44.4 4.2 3.3 3 0 0 3 3 3 3 LIM domain BOP1NT PF08145.7 EPY53888.1 - 9.9e-83 277.8 12.8 2.9e-81 273.0 8.8 2.3 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EPY53888.1 - 8.1e-27 92.1 19.6 4.2e-09 35.9 0.4 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EPY53888.1 - 0.029 14.6 0.1 1.1 9.6 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain DUF3312 PF11768.3 EPY53888.1 - 0.071 11.3 0.0 0.11 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) MFS_Mycoplasma PF07672.8 EPY53890.1 - 0.027 13.6 0.4 0.034 13.3 0.3 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter Adipogenin PF15202.1 EPY53890.1 - 0.27 11.1 2.1 0.29 11.0 0.7 1.8 2 0 0 2 2 2 0 Adipogenin MFS_1 PF07690.11 EPY53891.1 - 8e-40 136.6 54.6 2.3e-39 135.0 35.5 2.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPY53891.1 - 2.6e-07 29.5 11.0 2.6e-07 29.5 7.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4381 PF14316.1 EPY53891.1 - 0.39 10.8 6.1 0.25 11.4 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DIOX_N PF14226.1 EPY53892.1 - 3.6e-24 85.5 0.0 2.8e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPY53892.1 - 9.6e-15 54.6 0.1 1.6e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GXWXG PF14231.1 EPY53893.1 - 2.6e-23 81.4 0.1 5.9e-23 80.2 0.1 1.6 2 0 0 2 2 2 1 GXWXG protein DUF4334 PF14232.1 EPY53893.1 - 3.2e-22 77.9 1.6 8.2e-22 76.6 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) DIOX_N PF14226.1 EPY53895.1 - 2.9e-23 82.6 0.0 6.6e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPY53895.1 - 4.4e-11 42.9 0.0 7.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 EPY53897.1 - 3.9e-54 180.1 0.0 3.8e-16 58.4 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY53897.1 - 2e-35 120.5 0.0 3.2e-12 46.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY53897.1 - 9.3e-27 92.6 0.0 3.8e-12 45.8 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY53897.1 - 0.0088 15.7 0.0 1.4 8.7 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Rad10 PF03834.9 EPY53898.1 - 1.2e-29 101.7 0.0 2.2e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EPY53898.1 - 2.6e-06 27.5 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EPY53898.1 - 4.5e-06 26.0 0.0 1.3e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EPY53898.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HRDC PF00570.18 EPY53898.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 HRDC domain ERO1 PF04137.10 EPY53899.1 - 1e-110 370.1 7.3 1.4e-110 369.7 5.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Gemini_AL3 PF01407.12 EPY53899.1 - 0.0071 15.7 0.3 0.017 14.6 0.2 1.6 1 0 0 1 1 1 1 Geminivirus AL3 protein Fer4_18 PF13746.1 EPY53899.1 - 0.032 14.6 2.0 0.04 14.3 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_2 PF07724.9 EPY53900.1 - 2.5e-51 174.0 0.1 1.3e-48 165.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EPY53900.1 - 3.3e-26 90.9 0.2 1.4e-25 88.9 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EPY53900.1 - 3e-19 69.5 0.1 6.5e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPY53900.1 - 1.6e-15 57.5 5.4 1.1e-05 25.4 0.1 4.6 3 2 1 4 4 4 3 AAA ATPase domain AAA_5 PF07728.9 EPY53900.1 - 3.1e-13 49.6 0.0 2.9e-09 36.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPY53900.1 - 6.1e-10 39.3 3.2 0.00024 21.2 0.0 4.3 3 1 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EPY53900.1 - 5e-08 32.6 0.1 2.2e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPY53900.1 - 9.1e-08 31.7 0.1 0.031 13.6 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EPY53900.1 - 6.5e-07 29.2 6.6 0.0052 16.5 0.1 4.3 3 2 0 3 3 2 2 Archaeal ATPase AAA_14 PF13173.1 EPY53900.1 - 1.9e-06 27.8 0.0 0.1 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPY53900.1 - 1.9e-06 28.6 3.3 0.049 14.4 0.0 3.7 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 EPY53900.1 - 2.5e-06 27.2 0.3 0.037 13.6 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.1 EPY53900.1 - 3.1e-05 24.2 2.4 0.39 11.0 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 EPY53900.1 - 3.8e-05 23.7 0.3 2 8.3 0.0 4.2 4 1 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 EPY53900.1 - 5.1e-05 23.3 0.0 1.1 9.4 0.0 3.5 3 0 0 3 3 3 2 RNA helicase Mg_chelatase PF01078.16 EPY53900.1 - 5.3e-05 22.4 0.9 0.25 10.4 0.0 3.6 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EPY53900.1 - 0.00013 21.8 1.4 0.038 13.8 0.0 3.2 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit MobB PF03205.9 EPY53900.1 - 0.00025 20.7 0.0 0.54 9.9 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EPY53900.1 - 0.00028 21.1 0.6 0.19 12.0 0.0 3.3 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 EPY53900.1 - 0.00035 20.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPY53900.1 - 0.00043 19.5 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPY53900.1 - 0.00071 19.0 0.0 0.79 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPY53900.1 - 0.001 18.5 0.9 0.16 11.3 0.1 3.7 2 2 1 3 3 3 1 AAA-like domain MMR_HSR1 PF01926.18 EPY53900.1 - 0.0022 17.9 0.0 2.1 8.3 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RuvB_N PF05496.7 EPY53900.1 - 0.0043 16.1 1.5 0.43 9.5 0.0 3.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_21 PF13304.1 EPY53900.1 - 0.0045 16.9 0.0 2 8.3 0.1 3.4 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 EPY53900.1 - 0.0054 15.3 0.1 1.1 7.7 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EPY53900.1 - 0.0063 15.4 0.1 0.036 12.9 0.0 2.3 2 1 0 2 2 2 1 Type II/IV secretion system protein SRP54 PF00448.17 EPY53900.1 - 0.0083 15.5 0.1 2 7.7 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 EPY53900.1 - 0.0098 16.3 0.0 2.5 8.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein DNA_pol3_delta2 PF13177.1 EPY53900.1 - 0.01 15.4 0.0 0.11 12.2 0.0 2.6 3 1 0 3 3 2 0 DNA polymerase III, delta subunit ATP_bind_1 PF03029.12 EPY53900.1 - 0.012 15.2 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 EPY53900.1 - 0.017 14.6 0.0 1.6 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EPY53900.1 - 0.023 14.2 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPY53900.1 - 0.026 14.3 1.3 7.3 6.4 0.0 3.7 3 2 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EPY53900.1 - 0.086 12.3 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EPY53900.1 - 0.15 11.8 7.1 3.3 7.4 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF87 Torsin PF06309.6 EPY53900.1 - 0.19 11.6 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 Torsin IncA PF04156.9 EPY53900.1 - 0.71 9.4 10.6 1.8 8.0 7.3 1.6 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 EPY53900.1 - 1.3 8.5 7.7 2.5 7.6 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin PF02996.12 EPY53900.1 - 2 8.0 9.0 0.6 9.7 0.1 4.0 5 1 0 5 5 4 0 Prefoldin subunit AAA_23 PF13476.1 EPY53900.1 - 4 7.7 19.8 1 9.6 0.0 3.9 2 2 0 2 2 1 0 AAA domain Arf PF00025.16 EPY53901.1 - 4.6e-80 266.9 0.1 5.2e-80 266.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPY53901.1 - 5e-14 51.9 0.0 6.2e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPY53901.1 - 7.4e-13 48.1 0.0 8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPY53901.1 - 3.8e-12 45.6 1.0 9.5e-09 34.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPY53901.1 - 2e-11 43.4 0.0 2.4e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPY53901.1 - 3e-09 37.4 0.0 4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPY53901.1 - 4.9e-06 26.4 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EPY53901.1 - 0.0063 15.6 0.1 0.01 14.8 0.0 1.4 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EPY53901.1 - 0.014 14.8 0.1 0.096 12.1 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EPY53901.1 - 0.089 12.6 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Peptidase_M24 PF00557.19 EPY53902.1 - 6.6e-47 159.7 0.0 8.6e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EPY53902.1 - 4.2e-07 30.5 0.0 6.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Lung_7-TM_R PF06814.8 EPY53903.1 - 7.2e-51 172.8 16.5 9.4e-51 172.5 11.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Tmemb_14 PF03647.8 EPY53903.1 - 0.43 10.9 0.1 0.43 10.9 0.1 2.9 2 1 0 2 2 2 0 Transmembrane proteins 14C DUF4131 PF13567.1 EPY53903.1 - 7.5 5.9 15.9 0.47 9.8 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UvrD-helicase PF00580.16 EPY53904.1 - 5.2e-14 52.2 0.4 3e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EPY53904.1 - 9.8e-12 44.9 0.0 2.2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EPY53904.1 - 3.6e-08 33.2 0.1 0.038 13.5 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EPY53904.1 - 1.1e-06 28.6 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EPY53904.1 - 2.6e-06 27.1 0.0 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPY53904.1 - 4.4e-05 23.1 0.0 0.00015 21.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EPY53904.1 - 0.0062 15.7 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 EPY53904.1 - 0.029 13.9 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain RrnaAD PF00398.15 EPY53905.1 - 2.4e-60 203.7 0.0 2.8e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EPY53905.1 - 2.1e-11 43.8 0.0 3.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY53905.1 - 7.9e-07 28.7 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPY53905.1 - 1.6e-06 28.6 0.0 3.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPY53905.1 - 9.4e-06 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EPY53905.1 - 2.7e-05 24.5 0.0 5.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY53905.1 - 3.6e-05 23.5 0.0 0.00032 20.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPY53905.1 - 4.3e-05 22.9 0.0 6.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EPY53905.1 - 0.00023 20.3 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 EPY53905.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.7 EPY53905.1 - 0.0028 18.0 0.0 0.0061 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPY53905.1 - 0.0045 15.9 0.0 0.0077 15.1 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_2 PF00891.13 EPY53905.1 - 0.0073 15.5 0.1 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase PRMT5 PF05185.11 EPY53905.1 - 0.0078 15.1 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_25 PF13649.1 EPY53905.1 - 0.033 14.5 0.0 0.083 13.2 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EPY53905.1 - 0.055 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.1 EPY53905.1 - 0.056 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EPY53905.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 EPY53905.1 - 0.059 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EPY53905.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EPY53905.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RasGEF PF00617.14 EPY53906.1 - 7.1e-51 172.6 0.3 1.9e-50 171.2 0.2 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPY53906.1 - 2.8e-17 62.7 0.7 2.8e-17 62.7 0.5 3.5 3 0 0 3 3 3 1 RasGEF N-terminal motif DNA_pol_B PF00136.16 EPY53907.1 - 2e-146 488.4 0.1 2.8e-146 487.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPY53907.1 - 2.9e-92 309.0 0.4 4.3e-92 308.4 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPY53907.1 - 1.4e-25 89.1 6.7 3.5e-25 87.8 4.6 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EPY53907.1 - 0.0039 15.9 2.1 0.0047 15.6 0.4 1.8 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 EPY53907.1 - 0.0043 16.8 0.1 0.019 14.7 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.15 EPY53907.1 - 0.08 12.4 0.2 0.32 10.4 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease C1_1 PF00130.17 EPY53907.1 - 3.8 7.3 7.1 8.8 6.1 0.5 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNase_H PF00075.19 EPY53908.1 - 3.9e-29 101.6 0.0 5.5e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EPY53908.1 - 5.7e-17 61.4 0.6 1.1e-16 60.5 0.4 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3303 PF11746.3 EPY53908.1 - 0.054 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3303) Spc7_N PF15402.1 EPY53908.1 - 4.8 5.0 7.0 2.1 6.2 3.5 1.3 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 Ras PF00071.17 EPY53909.1 - 1.5e-65 219.5 0.7 1.9e-65 219.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY53909.1 - 2.8e-22 79.4 0.0 4.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY53909.1 - 1.4e-17 63.4 0.1 1.7e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY53909.1 - 1.2e-06 27.8 0.1 1.6e-06 27.4 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPY53909.1 - 1.9e-06 27.4 0.2 4.1e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EPY53909.1 - 1.8e-05 24.0 0.1 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPY53909.1 - 5.4e-05 23.1 0.1 8.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EPY53909.1 - 0.00042 20.5 0.1 0.079 13.1 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY53909.1 - 0.00077 19.6 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPY53909.1 - 0.0054 16.7 0.1 0.053 13.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EPY53909.1 - 0.01 15.5 0.2 0.08 12.6 0.0 2.2 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 EPY53909.1 - 0.012 14.9 0.1 0.11 11.8 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EPY53909.1 - 0.02 14.0 0.1 0.062 12.4 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPY53909.1 - 0.034 14.4 0.2 0.099 12.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EPY53909.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EPY53909.1 - 0.042 13.3 0.1 1 8.8 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EPY53909.1 - 0.043 12.8 0.1 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 EPY53909.1 - 0.049 13.5 0.5 0.22 11.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 EPY53909.1 - 1.4 7.5 4.8 5.8 5.4 0.6 2.6 1 1 1 2 2 2 0 G-protein alpha subunit OPA3 PF07047.7 EPY53910.1 - 1e-34 119.1 0.6 1e-34 119.1 0.4 1.7 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Allexi_40kDa PF05549.6 EPY53910.1 - 0.16 11.2 2.6 0.26 10.5 1.8 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein CDK5_activator PF03261.10 EPY53910.1 - 0.29 10.4 5.6 0.46 9.7 3.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein UCH PF00443.24 EPY53911.1 - 1.9e-64 217.3 3.2 1.9e-64 217.3 2.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY53911.1 - 1.1e-31 110.4 5.7 1.7e-29 103.2 2.2 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DDE_1 PF03184.14 EPY53912.1 - 1.2e-58 197.8 0.2 1.8e-58 197.2 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Arch_fla_DE PF04659.8 EPY53912.1 - 0.08 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Archaeal flagella protein Mito_carr PF00153.22 EPY53915.1 - 3.1e-47 158.2 6.0 5.4e-17 61.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Topoisom_I_N PF02919.10 EPY53916.1 - 1.3e-102 341.6 5.2 1.3e-102 341.6 3.6 2.6 3 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EPY53916.1 - 1.5e-84 282.7 1.7 1.5e-84 282.7 1.2 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EPY53916.1 - 6.4e-29 99.4 1.9 6.4e-29 99.4 1.3 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain Sec1 PF00995.18 EPY53917.1 - 1.5e-90 304.4 0.6 1.7e-90 304.3 0.4 1.0 1 0 0 1 1 1 1 Sec1 family WD40 PF00400.27 EPY53918.1 - 2.3e-09 36.7 12.6 2e-07 30.6 0.4 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPY53918.1 - 0.17 10.6 0.0 1.2 7.8 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region zf-RING_2 PF13639.1 EPY53919.1 - 3.8e-14 52.2 21.8 1.6e-11 43.7 5.3 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 EPY53919.1 - 8e-09 35.3 19.9 6.8e-07 29.2 6.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPY53919.1 - 1.1e-08 34.6 18.5 3.9e-06 26.4 4.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY53919.1 - 6.5e-08 32.1 20.6 0.00011 21.8 4.8 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.2 EPY53919.1 - 5e-06 26.5 15.0 3.1e-05 24.0 2.8 2.4 2 0 0 2 2 2 2 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPY53919.1 - 1.6e-05 24.5 4.1 1.6e-05 24.5 2.9 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EPY53919.1 - 6.4e-05 22.5 22.2 0.0008 19.0 6.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPY53919.1 - 0.0013 18.2 21.1 0.039 13.5 3.6 2.3 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EPY53919.1 - 0.042 13.6 13.2 0.27 11.1 1.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exo70 PF03081.10 EPY53919.1 - 0.088 11.5 0.4 0.14 10.9 0.3 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit zf-C3HC4_4 PF15227.1 EPY53919.1 - 0.21 11.4 16.3 1.6 8.6 4.6 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF846 PF05832.7 EPY53920.1 - 1.1e-48 164.5 7.1 1.4e-48 164.2 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.1 EPY53920.1 - 0.54 9.3 2.5 0.82 8.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) NfeD PF01957.13 EPY53920.1 - 1.1 9.4 7.2 5.4 7.1 2.3 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Prenyltransf PF01255.14 EPY53921.1 - 4.4e-09 35.8 0.0 1.1e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase zf-PARP PF00645.13 EPY53922.1 - 6.4e-21 74.3 0.2 1.4e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Longin PF13774.1 EPY53924.1 - 7.9e-27 92.6 0.0 7.9e-27 92.6 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPY53924.1 - 3.5e-17 61.7 0.0 5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Phosducin PF02114.11 EPY53925.1 - 1.5e-22 79.5 0.1 3.3e-22 78.4 0.1 1.5 1 1 1 2 2 2 1 Phosducin Thioredoxin PF00085.15 EPY53925.1 - 0.00029 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Bin3 PF06859.7 EPY53926.1 - 2.4e-32 111.1 0.1 4e-32 110.4 0.1 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 EPY53926.1 - 9.6e-14 51.4 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY53926.1 - 1.7e-13 50.3 0.0 5.4e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EPY53926.1 - 3.3e-11 43.7 0.0 6.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY53926.1 - 1.3e-08 35.1 0.0 0.00051 20.4 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EPY53926.1 - 1.2e-07 32.1 0.0 0.0016 18.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EPY53926.1 - 6.4e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY53926.1 - 0.00013 22.2 0.0 0.00077 19.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPY53926.1 - 0.00023 20.2 0.0 0.0015 17.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EPY53926.1 - 0.00032 20.1 0.0 0.0033 16.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EPY53926.1 - 0.0012 18.0 0.1 0.0026 16.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EPY53926.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 EPY53926.1 - 0.0016 17.5 0.0 1.2 8.1 0.0 2.3 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.7 EPY53926.1 - 0.0054 16.0 0.0 0.019 14.2 0.0 1.8 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase NodS PF05401.6 EPY53926.1 - 0.013 14.8 0.0 0.44 9.8 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) PCMT PF01135.14 EPY53926.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spermine_synth PF01564.12 EPY53926.1 - 0.019 13.8 0.0 0.66 8.8 0.0 2.1 2 0 0 2 2 2 0 Spermine/spermidine synthase Methyltransf_32 PF13679.1 EPY53926.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SAC3_GANP PF03399.11 EPY53927.1 - 1.2e-63 214.4 0.7 1.6e-63 213.9 0.5 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPY53927.1 - 2.8e-07 30.3 4.2 3.4e-07 30.1 0.1 2.8 3 1 0 3 3 3 1 COP9 signalosome, subunit CSN8 ORC6 PF05460.8 EPY53928.1 - 1.9e-24 86.4 3.8 1.1e-20 74.0 0.1 2.0 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) DUF866 PF05907.8 EPY53929.1 - 1.1e-50 171.2 0.5 1.3e-50 171.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 EPY53929.1 - 0.01 15.4 0.7 0.025 14.1 0.5 1.6 1 1 0 1 1 1 0 Cytochrome c7 Basic PF01586.11 EPY53929.1 - 0.036 14.7 1.6 0.066 13.9 1.1 1.6 1 1 0 1 1 1 0 Myogenic Basic domain DUF3716 PF12511.3 EPY53929.1 - 0.25 10.9 2.3 0.28 10.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) zf-C4pol PF14260.1 EPY53929.1 - 0.93 9.5 4.8 4.4 7.3 3.5 1.9 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Elf1 PF05129.8 EPY53929.1 - 1.1 9.0 4.2 1.3 8.7 0.3 2.2 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Arrestin_C PF02752.17 EPY53930.1 - 5.2e-19 68.7 0.1 5e-17 62.2 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPY53930.1 - 1.3e-11 44.4 0.0 6.7e-11 42.2 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Peptidase_S24 PF00717.18 EPY53933.1 - 9.3e-10 38.0 0.1 2.2e-09 36.8 0.0 1.6 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 EPY53933.1 - 7.1e-06 25.5 0.0 0.00014 21.4 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Ribosomal_L4 PF00573.17 EPY53934.1 - 7e-49 165.8 0.0 8.1e-49 165.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family SLAP PF03217.9 EPY53934.1 - 0.018 15.2 0.0 0.048 13.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial surface layer protein ECH PF00378.15 EPY53935.1 - 5.5e-33 114.0 0.0 1.6e-31 109.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EPY53935.1 - 1.8e-24 86.1 0.0 3e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Fibrillarin PF01269.12 EPY53936.1 - 1.8e-107 357.4 0.0 2.3e-107 357.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EPY53936.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EPY53936.1 - 0.055 13.0 0.1 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EPY53936.1 - 0.098 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EPY53936.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase NAP PF00956.13 EPY53937.1 - 2.7e-75 252.6 2.4 2.7e-75 252.6 1.7 1.7 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) XPC-binding PF09280.6 EPY53938.1 - 1.3e-25 88.5 8.7 2.9e-25 87.4 6.0 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EPY53938.1 - 2.7e-21 74.7 1.6 4.5e-21 74.0 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EPY53938.1 - 1.8e-20 72.1 4.3 3.9e-10 39.2 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EPY53938.1 - 2.1e-09 36.9 2.4 3.7e-09 36.1 1.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPY53938.1 - 3.3e-05 23.9 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPY53938.1 - 0.00021 21.1 0.1 0.00049 19.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rap1_C PF11626.3 EPY53938.1 - 0.0069 16.2 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MCM_N PF14551.1 EPY53938.1 - 0.0072 16.8 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain UBA_3 PF09288.5 EPY53938.1 - 0.028 14.0 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain SOG2 PF10428.4 EPY53938.1 - 0.032 12.9 9.1 0.044 12.4 6.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Phosphoprotein PF00922.12 EPY53938.1 - 0.067 12.3 3.0 0.12 11.6 2.1 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein DUF3135 PF11333.3 EPY53938.1 - 0.15 12.2 3.4 0.37 10.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3135) RAP1 PF07218.6 EPY53938.1 - 0.51 8.3 1.8 0.55 8.2 1.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.7 EPY53938.1 - 1.7 8.5 18.6 2.3 8.0 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EST1 PF10374.4 EPY53939.1 - 3.9e-17 62.4 5.1 1.2e-16 60.9 3.6 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.4 EPY53939.1 - 6.2e-16 58.4 3.8 6.2e-16 58.4 2.6 3.0 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Myosin_head PF00063.16 EPY53940.1 - 4e-227 755.5 7.6 4e-227 755.5 5.3 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EPY53940.1 - 7.9e-22 77.1 0.3 2.4e-21 75.5 0.2 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EPY53940.1 - 1.9e-17 61.1 13.9 0.00013 21.3 0.1 6.5 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 EPY53940.1 - 0.0013 18.8 0.0 0.0062 16.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EPY53940.1 - 0.021 13.8 0.1 0.021 13.8 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EPY53940.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EPY53940.1 - 0.045 13.7 0.1 0.51 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Pept_tRNA_hydro PF01195.14 EPY53941.1 - 4.8e-31 107.6 0.0 6e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase CENP-S PF15630.1 EPY53942.1 - 9e-26 89.8 0.1 1.2e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EPY53942.1 - 7.5e-05 22.3 0.0 0.00058 19.5 0.0 2.1 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.19 EPY53942.1 - 0.00014 21.8 0.1 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 EPY53942.1 - 0.0012 18.2 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EPY53942.1 - 0.0026 17.8 0.0 0.0051 16.8 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 EPY53942.1 - 0.054 13.3 0.5 0.097 12.4 0.2 1.6 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF4583 PF15190.1 EPY53943.1 - 0.0018 17.9 0.4 0.0023 17.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4583) DUF1673 PF07895.6 EPY53943.1 - 0.0094 15.5 0.7 0.011 15.2 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) WTF PF03303.8 EPY53943.1 - 0.02 14.2 0.4 0.023 14.1 0.3 1.0 1 0 0 1 1 1 0 WTF protein DUF3669 PF12417.3 EPY53943.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger protein DUF2207 PF09972.4 EPY53943.1 - 0.093 11.3 0.9 0.1 11.1 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 EPY53943.1 - 2.1 8.3 5.9 3.5 7.6 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF3810 PF12725.2 EPY53943.1 - 4.7 6.0 6.0 5.4 5.8 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ABC1 PF03109.11 EPY53945.1 - 4.2e-35 120.3 0.0 1.3e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 ABC1 family UQ_con PF00179.21 EPY53947.1 - 6.1e-44 148.8 0.1 8.1e-44 148.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EPY53947.1 - 1.3e-07 31.0 0.2 2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA PF00627.26 EPY53947.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Kinesin PF00225.18 EPY53948.1 - 9.4e-70 234.9 0.0 9.4e-70 234.9 0.0 1.9 2 1 0 2 2 2 1 Kinesin motor domain Zn_clus PF00172.13 EPY53949.1 - 0.0002 21.1 6.0 0.00041 20.1 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neisseria_TspB PF05616.8 EPY53949.1 - 6 5.1 13.4 8.3 4.6 9.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Hira PF07569.6 EPY53950.1 - 5e-68 228.5 0.0 1.4e-67 227.0 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EPY53950.1 - 1.6e-18 65.8 10.3 3.1e-07 30.0 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat SID-1_RNA_chan PF13965.1 EPY53950.1 - 0.082 11.0 0.1 0.13 10.4 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glycos_transf_4 PF00953.16 EPY53951.1 - 5.2e-32 110.8 12.9 1.3e-31 109.5 9.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 4 cobW PF02492.14 EPY53952.1 - 6.6e-47 159.2 0.6 9e-47 158.8 0.4 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EPY53952.1 - 3e-06 26.8 0.0 6.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.1 EPY53952.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 EPY53952.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EPY53952.1 - 0.024 14.0 0.1 0.09 12.1 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain ArgK PF03308.11 EPY53952.1 - 0.027 13.2 2.2 6.1 5.5 0.3 2.8 2 1 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 EPY53952.1 - 0.032 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EPY53952.1 - 0.051 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EPY53952.1 - 0.065 12.7 0.5 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EPY53952.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EPY53952.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Acetyltransf_1 PF00583.19 EPY53953.1 - 1.7e-16 59.9 0.1 2.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPY53953.1 - 1.1e-10 41.4 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPY53953.1 - 1.5e-10 41.2 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPY53953.1 - 5.3e-09 35.7 0.1 7.6e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EPY53953.1 - 1.4e-08 34.7 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPY53953.1 - 1.7e-07 31.4 0.0 2.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPY53953.1 - 6.9e-06 25.9 0.1 9.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPY53953.1 - 9.2e-05 22.4 0.1 0.00012 22.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPY53953.1 - 0.00091 19.0 0.1 0.0032 17.3 0.0 1.9 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase APG9 PF04109.11 EPY53954.1 - 2.5e-143 477.4 9.4 3.7e-143 476.9 6.5 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Cys_Met_Meta_PP PF01053.15 EPY53955.1 - 2.9e-34 117.9 0.0 4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPY53955.1 - 0.053 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II zf-CCCH PF00642.19 EPY53956.1 - 0.0021 17.6 1.6 0.0034 17.0 1.1 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MAM33 PF02330.11 EPY53957.1 - 3e-08 33.6 0.3 3.4e-08 33.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3779 PF12621.3 EPY53958.1 - 0.19 11.6 3.3 0.32 10.8 1.4 2.0 1 1 1 2 2 2 0 Phosphate metabolism protein Ripply PF14998.1 EPY53958.1 - 0.28 11.3 2.3 0.27 11.3 0.9 1.5 1 1 0 1 1 1 0 Transcription Regulator AKAP7_NLS PF10469.4 EPY53959.1 - 2.7e-26 92.5 0.0 3.5e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EPY53959.1 - 0.07 12.8 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily WD40 PF00400.27 EPY53960.1 - 1.7e-53 176.6 14.4 1.8e-10 40.2 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EPY53960.1 - 7.6e-43 146.0 0.5 1.3e-42 145.2 0.4 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EPY53960.1 - 0.0014 16.8 0.8 0.37 8.8 0.1 3.1 1 1 0 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.6 EPY53960.1 - 0.0044 16.7 0.1 0.013 15.2 0.1 1.9 1 0 0 1 1 1 1 LisH Hydrolase_6 PF13344.1 EPY53961.1 - 1.7e-28 98.4 0.0 3.2e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPY53961.1 - 3.3e-14 52.3 0.0 6.9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPY53961.1 - 1.6e-13 51.5 0.0 2.8e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPY53961.1 - 3.6e-07 30.5 0.0 0.044 13.9 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EPY53961.1 - 0.04 13.2 0.0 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase PNK3P PF08645.6 EPY53961.1 - 0.047 13.1 0.0 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase MIF4G PF02854.14 EPY53962.1 - 1.2e-30 106.5 0.8 1.2e-30 106.5 0.5 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EPY53962.1 - 2.3e-26 91.6 0.0 4.5e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 MA3 domain Phtf-FEM1B_bdg PF12129.3 EPY53962.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Acetyltransf_1 PF00583.19 EPY53963.1 - 8e-12 45.0 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPY53963.1 - 9.8e-09 35.3 0.0 1.9e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 EPY53963.1 - 5.2e-08 32.3 2.0 1e-07 31.4 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EPY53963.1 - 4.1e-07 29.9 12.2 7.9e-07 29.0 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Acetyltransf_7 PF13508.1 EPY53963.1 - 5.1e-07 29.7 0.1 3e-06 27.3 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain zf-C3HC4_3 PF13920.1 EPY53963.1 - 8.7e-06 25.3 7.8 1.7e-05 24.3 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY53963.1 - 0.00031 20.3 13.2 0.00062 19.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPY53963.1 - 0.001 18.7 10.9 0.0021 17.7 7.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF3749 PF12568.3 EPY53963.1 - 0.0045 16.5 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 EPY53963.1 - 0.011 15.5 9.6 0.021 14.6 6.6 1.5 1 0 0 1 1 1 0 Ring finger domain LSM PF01423.17 EPY53963.1 - 0.013 14.9 0.4 0.05 13.1 0.2 1.9 2 0 0 2 2 2 0 LSM domain zf-C3HC4_4 PF15227.1 EPY53963.1 - 0.071 12.9 6.8 0.22 11.3 4.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPY53963.1 - 0.37 10.5 8.3 0.66 9.7 4.8 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EPY53963.1 - 2.5 7.6 8.1 2.5 7.6 4.7 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.12 EPY53964.1 - 7.4e-14 51.3 0.4 4.6e-13 48.8 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPY53964.1 - 9.5e-09 35.3 0.0 2.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ATP-synt_DE_N PF02823.11 EPY53965.1 - 2.2e-20 72.1 0.0 3.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Mannosyl_trans PF05007.8 EPY53966.1 - 8e-88 294.4 24.0 2.5e-87 292.8 16.6 1.9 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EPY53966.1 - 4.2e-06 25.8 25.6 4.2e-06 25.8 17.7 3.1 2 2 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EPY53966.1 - 0.00024 20.6 6.1 0.00024 20.6 4.2 2.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2029) ADIP PF11559.3 EPY53967.1 - 1.5e-13 50.9 22.9 1.5e-13 50.9 15.9 2.7 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding MCC-bdg_PDZ PF10506.4 EPY53967.1 - 0.11 12.2 8.8 0.83 9.5 1.0 3.8 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FtsL PF04999.8 EPY53967.1 - 8.4 6.1 10.8 28 4.5 0.2 2.6 2 0 0 2 2 2 0 Cell division protein FtsL Macoilin PF09726.4 EPY53968.1 - 2.2 6.4 28.7 2.7 6.1 19.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Leo1 PF04004.8 EPY53969.1 - 1.3e-39 135.6 1.1 1.3e-39 135.6 0.7 2.7 3 0 0 3 3 3 1 Leo1-like protein WH2 PF02205.15 EPY53970.1 - 3.2e-12 45.6 3.7 5.8e-11 41.6 1.1 2.3 2 0 0 2 2 2 2 WH2 motif TFIIB PF00382.14 EPY53971.1 - 1e-34 118.1 2.3 4.4e-18 64.8 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EPY53971.1 - 1.3e-25 89.4 7.1 1.3e-25 89.4 5.0 2.0 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EPY53971.1 - 2e-10 39.7 1.0 4.2e-10 38.7 0.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EPY53971.1 - 1.1e-06 28.2 0.3 0.012 15.1 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 EPY53971.1 - 0.48 9.7 3.4 1.2 8.4 2.4 1.7 1 1 0 1 1 1 0 zinc-ribbon domain RRN7 PF11781.3 EPY53971.1 - 0.77 9.3 3.9 0.43 10.1 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Rhomboid PF01694.17 EPY53972.1 - 7e-20 71.5 16.8 7e-20 71.5 11.7 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1122 PF06557.6 EPY53972.1 - 0.11 11.5 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Ribosomal_L1 PF00687.16 EPY53973.1 - 1.1e-49 168.7 1.1 1.4e-49 168.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SMI1_KNR4 PF09346.5 EPY53974.1 - 2.1e-32 111.8 0.0 4.3e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PDT PF00800.13 EPY53975.1 - 1.2e-59 200.9 0.0 1.6e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase Gar1 PF04410.9 EPY53976.1 - 8.8e-46 155.1 0.8 2.2e-45 153.8 0.5 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RAP1 PF07218.6 EPY53976.1 - 3.9 5.4 17.9 0.025 12.7 6.3 1.7 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.9 EPY53976.1 - 5.3 4.9 15.2 0.66 7.9 4.2 2.3 2 0 0 2 2 2 0 CDC45-like protein DLH PF01738.13 EPY53977.1 - 6.8e-16 58.2 0.0 7.6e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPY53977.1 - 1.9e-07 30.9 0.0 2.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPY53977.1 - 0.034 14.0 0.1 1.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Transket_pyr PF02779.19 EPY53978.1 - 3.1e-45 153.8 0.1 1.9e-44 151.2 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPY53978.1 - 2.4e-36 124.3 0.8 4.7e-36 123.4 0.5 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain MRP-S33 PF08293.6 EPY53979.1 - 3.7e-17 62.0 0.1 4.6e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.10 EPY53980.1 - 8.4e-67 224.5 16.3 1.9e-66 223.3 11.3 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) FAT PF02259.18 EPY53981.1 - 4.2e-109 364.7 1.8 4.2e-109 364.7 1.3 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EPY53981.1 - 6e-60 202.6 0.9 1.1e-59 201.7 0.6 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EPY53981.1 - 9.2e-45 152.4 8.4 3.6e-44 150.5 1.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EPY53981.1 - 1.6e-38 130.7 0.9 1.6e-38 130.7 0.6 3.2 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EPY53981.1 - 6.8e-17 61.5 1.0 0.002 18.3 0.0 8.2 5 1 2 7 7 7 3 HEAT repeats FATC PF02260.15 EPY53981.1 - 9.7e-14 50.5 0.2 2.1e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EPY53981.1 - 1e-11 43.8 14.5 0.085 12.9 0.0 10.1 11 0 0 11 11 10 2 HEAT repeat HEAT_EZ PF13513.1 EPY53981.1 - 1.3e-05 25.4 14.1 0.67 10.5 0.0 8.9 7 2 2 10 10 9 2 HEAT-like repeat TPR_16 PF13432.1 EPY53981.1 - 0.13 12.9 2.6 3.4 8.4 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPY53981.1 - 0.16 11.8 4.3 11 6.1 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPY53981.1 - 1.6 8.8 6.0 33 4.7 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TB2_DP1_HVA22 PF03134.14 EPY53982.1 - 5.5e-22 77.3 2.2 4.3e-21 74.4 1.6 2.0 1 1 0 1 1 1 1 TB2/DP1, HVA22 family EOS1 PF12326.3 EPY53982.1 - 0.15 11.7 5.0 1.1 8.8 2.7 2.3 1 1 1 2 2 2 0 N-glycosylation protein IBV_3C PF03620.8 EPY53982.1 - 0.15 12.0 0.6 0.24 11.3 0.3 1.4 1 1 0 1 1 1 0 IBV 3C protein Mgm101p PF06420.7 EPY53983.1 - 1.4e-91 304.4 0.0 1.8e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.4 EPY53984.1 - 6e-103 344.4 0.0 7.6e-103 344.1 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EPY53984.1 - 4e-27 94.6 0.0 9.3e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family LSM PF01423.17 EPY53985.1 - 4.7e-16 58.0 0.0 6.8e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF3602 PF12223.3 EPY53985.1 - 0.028 14.7 2.1 0.048 14.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) SM-ATX PF14438.1 EPY53985.1 - 0.057 13.3 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Complex1_LYR PF05347.10 EPY53986.1 - 0.00044 19.9 0.4 0.00095 18.9 0.1 1.7 1 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPY53986.1 - 0.0052 16.9 0.0 0.0064 16.6 0.0 1.3 1 1 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 EPY53986.1 - 0.08 12.6 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Swi3 PF07962.7 EPY53987.1 - 9.8e-27 92.4 0.1 1.5e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 ISN1 PF06437.6 EPY53988.1 - 8.8e-165 548.3 0.0 9.9e-165 548.1 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase FTA4 PF13093.1 EPY53988.1 - 0.058 12.8 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CBFD_NFYB_HMF PF00808.18 EPY53989.1 - 5.6e-20 71.1 1.0 5.6e-20 71.1 0.7 2.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPY53989.1 - 0.00094 19.2 0.3 0.0021 18.1 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EPY53989.1 - 0.29 10.9 1.9 1.1 9.1 0.8 2.4 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF3510 PF12022.3 EPY53989.1 - 0.39 10.8 3.1 0.67 10.0 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) ING PF12998.2 EPY53989.1 - 3.3 8.0 7.8 10 6.4 3.3 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DnaJ PF00226.26 EPY53990.1 - 5.3e-20 70.9 2.2 1.6e-19 69.4 1.5 1.9 1 0 0 1 1 1 1 DnaJ domain Trp_dioxygenase PF03301.8 EPY53990.1 - 0.0036 16.4 2.9 0.0036 16.4 2.0 1.9 2 0 0 2 2 2 1 Tryptophan 2,3-dioxygenase DUF3292 PF11696.3 EPY53990.1 - 0.24 9.2 6.7 0.49 8.2 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Rap1-DNA-bind PF09197.5 EPY53991.1 - 0.00016 22.1 2.5 0.00051 20.5 0.0 2.9 3 0 0 3 3 3 1 Rap1, DNA-binding NUDIX PF00293.23 EPY53992.1 - 3.1e-15 56.0 0.1 1.1e-14 54.2 0.0 1.8 2 1 1 3 3 3 1 NUDIX domain NUDIX-like PF09296.6 EPY53992.1 - 3.5e-12 46.5 0.0 6.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EPY53992.1 - 5.3e-07 29.0 0.9 1e-06 28.0 0.6 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Dfp1_Him1_M PF08630.5 EPY53994.1 - 7.5e-30 103.2 0.0 1.6e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EPY53994.1 - 2.6e-19 68.6 1.7 5.4e-19 67.6 1.2 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EPY53994.1 - 0.00029 20.9 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-C2H2_2 PF12756.2 EPY53994.1 - 0.0065 16.5 0.2 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) PTCB-BRCT PF12738.2 EPY53994.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain CH PF00307.26 EPY53995.1 - 1.2e-68 228.0 0.1 2.9e-19 69.0 0.4 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EPY53995.1 - 1.9e-10 40.2 0.0 0.032 13.8 0.0 4.4 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_1 PF00036.27 EPY53995.1 - 3.3e-08 32.2 1.9 0.0016 17.5 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EPY53995.1 - 9.5e-07 28.8 1.6 2.7e-06 27.3 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EPY53995.1 - 0.00028 20.5 2.6 0.42 10.6 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EPY53995.1 - 0.0014 18.2 1.6 0.45 10.1 0.1 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPY53995.1 - 0.079 12.3 3.2 4.7 6.7 0.1 3.2 3 0 0 3 3 3 0 EF hand N2227 PF07942.7 EPY53996.1 - 1.3e-105 352.2 1.4 1.8e-105 351.8 0.4 1.5 2 0 0 2 2 2 1 N2227-like protein Methyltransf_23 PF13489.1 EPY53996.1 - 0.00025 20.7 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY53996.1 - 0.15 12.5 0.4 1.3 9.5 0.1 2.7 2 1 0 2 2 2 0 Methyltransferase domain P21-Arc PF04062.9 EPY53997.1 - 2.1e-80 268.5 0.0 2.3e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit RabGAP-TBC PF00566.13 EPY53998.1 - 3.7e-34 118.0 0.6 7.3e-34 117.1 0.3 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EPY53999.1 - 6.7e-61 205.6 0.0 8.5e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY53999.1 - 1.2e-32 113.0 0.0 1.6e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EPY53999.1 - 1.7e-05 24.6 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EPY53999.1 - 0.00023 20.2 0.0 0.0015 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPY53999.1 - 0.0018 18.0 0.0 0.0057 16.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPY53999.1 - 0.0052 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPY53999.1 - 0.0075 15.6 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EPY53999.1 - 0.0075 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Proteasome PF00227.21 EPY54000.1 - 2.1e-49 167.3 1.0 2.5e-49 167.1 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit Glyco_transf_8 PF01501.15 EPY54001.1 - 6.7e-11 41.9 0.2 1.7e-10 40.6 0.2 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPY54001.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EPY54002.1 - 1.3e-13 50.8 4.1 2.9e-13 49.7 2.8 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 JAB PF01398.16 EPY54003.1 - 7e-21 74.0 0.0 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPY54003.1 - 3e-15 56.3 0.0 5.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function muHD PF10291.4 EPY54004.1 - 7.6e-22 77.7 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EPY54004.1 - 9.3e-12 44.9 0.8 3.4e-11 43.1 0.5 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Glyco_hydro_35 PF01301.14 EPY54004.1 - 0.038 13.3 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Seryl_tRNA_N PF02403.17 EPY54004.1 - 0.12 12.3 0.4 0.4 10.7 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RNA_pol_Rpb1_5 PF04998.12 EPY54005.1 - 5.1e-98 327.7 0.2 1.1e-97 326.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPY54005.1 - 3.9e-63 212.3 0.1 1.3e-62 210.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPY54005.1 - 3.5e-37 127.5 0.0 9.8e-37 126.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EPY54005.1 - 1.7e-26 93.3 16.7 9.3e-25 87.5 2.7 4.7 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EPY54005.1 - 1.5e-22 79.3 0.5 6.7e-22 77.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Asn_synthase PF00733.16 EPY54005.1 - 0.0027 17.2 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase CDC45 PF02724.9 EPY54005.1 - 0.59 8.1 15.6 0.054 11.5 0.6 2.2 2 0 0 2 2 2 0 CDC45-like protein Fork_head PF00250.13 EPY54006.1 - 2.5e-35 120.3 0.1 4.7e-35 119.5 0.1 1.4 1 0 0 1 1 1 1 Fork head domain Mss4 PF04421.8 EPY54007.1 - 3.3e-23 81.3 0.0 3.6e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Mss4 protein Mu-like_Com PF10122.4 EPY54007.1 - 1 8.4 3.4 7 5.7 0.1 2.5 3 0 0 3 3 3 0 Mu-like prophage protein Com GHMP_kinases_N PF00288.21 EPY54008.1 - 3.9e-12 46.0 0.0 7.5e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPY54008.1 - 0.0009 19.3 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GARS_A PF01071.14 EPY54009.1 - 5.7e-82 273.9 0.0 1.9e-81 272.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.17 EPY54009.1 - 1.7e-34 119.0 0.0 3.7e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.10 EPY54009.1 - 2.4e-32 111.3 0.1 3.8e-31 107.5 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EPY54009.1 - 1.5e-27 95.5 0.1 3.1e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EPY54009.1 - 4.1e-17 62.1 0.5 1.6e-16 60.3 0.3 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EPY54009.1 - 5.3e-08 32.8 0.0 4.9e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPY54009.1 - 1.1e-06 27.7 0.0 2.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EPY54009.1 - 4.2e-05 22.9 0.0 0.0001 21.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EPY54009.1 - 0.00023 20.5 0.0 0.00046 19.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 EPY54009.1 - 0.0074 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Vma12 PF11712.3 EPY54010.1 - 0.043 13.5 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TPT PF03151.11 EPY54011.1 - 9.4e-10 38.3 27.2 1.4e-06 28.0 4.0 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EPY54011.1 - 1.2e-07 31.8 38.3 0.00015 21.7 4.7 3.2 3 0 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 EPY54011.1 - 1.7e-07 31.4 27.5 0.00024 21.2 2.4 3.5 3 1 0 3 3 3 2 Multidrug resistance efflux transporter DUF914 PF06027.7 EPY54011.1 - 2.5e-05 23.3 16.4 3.7e-05 22.7 11.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EPY54011.1 - 0.03 13.2 18.0 0.08 11.8 12.5 1.9 1 1 0 1 1 1 0 UAA transporter family Ras PF00071.17 EPY54012.1 - 6.1e-58 194.7 0.2 7.1e-58 194.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPY54012.1 - 1.1e-18 67.8 0.0 1.9e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPY54012.1 - 1.6e-12 47.0 0.0 1.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPY54012.1 - 1.8e-08 33.8 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPY54012.1 - 3.7e-07 30.0 0.0 5.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPY54012.1 - 5.3e-07 29.2 0.0 4.1e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EPY54012.1 - 0.0001 21.9 0.4 0.0029 17.1 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EPY54012.1 - 0.00034 20.7 0.0 0.0011 19.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EPY54012.1 - 0.0021 17.2 0.1 0.0051 16.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EPY54012.1 - 0.004 16.3 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EPY54012.1 - 0.01 15.5 0.9 0.017 14.8 0.1 1.6 2 0 0 2 2 2 0 Archaeal ATPase Septin PF00735.13 EPY54012.1 - 0.011 14.8 0.1 0.034 13.1 0.0 1.8 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 EPY54012.1 - 0.013 15.0 0.1 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EPY54012.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 EPY54012.1 - 0.021 14.2 0.1 0.12 11.8 0.0 1.9 1 1 2 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EPY54012.1 - 0.022 14.3 0.2 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EPY54012.1 - 0.028 13.1 0.1 0.48 9.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.10 EPY54012.1 - 0.036 13.7 0.1 0.066 12.9 0.0 1.5 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 EPY54012.1 - 0.038 13.4 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EPY54012.1 - 0.046 13.8 0.1 0.36 11.0 0.0 2.2 2 1 0 2 2 2 0 RNA helicase MobB PF03205.9 EPY54012.1 - 0.054 13.1 0.5 0.091 12.4 0.1 1.7 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EPY54012.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EPY54012.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 EPY54012.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EPY54012.1 - 0.18 12.0 1.8 2 8.7 1.3 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPY54012.1 - 0.2 11.9 0.7 0.29 11.4 0.5 1.7 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.6 EPY54013.1 - 1.5e-10 41.2 10.3 1.5e-05 24.9 0.2 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF641 PF04859.7 EPY54013.1 - 0.058 13.1 3.8 0.11 12.2 2.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Acetyltransf_11 PF13720.1 EPY54013.1 - 0.086 13.0 0.7 0.21 11.8 0.1 1.8 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DnaJ PF00226.26 EPY54014.1 - 4.4e-21 74.3 1.6 7.1e-21 73.7 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPY54014.1 - 2.3e-17 62.6 0.0 4.9e-16 58.3 0.0 2.6 2 1 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPY54014.1 - 2.1e-12 46.8 18.6 3.9e-12 46.0 12.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Complex1_30kDa PF00329.14 EPY54014.1 - 0.027 14.6 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Thg1C PF14413.1 EPY54014.1 - 0.095 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Thg1 C terminal domain HypA PF01155.14 EPY54014.1 - 0.11 12.1 5.8 2.4 7.8 0.8 2.6 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 EPY54014.1 - 0.31 10.7 2.9 10 5.9 0.1 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_3 PF14369.1 EPY54014.1 - 5.1 7.1 7.3 2.3 8.3 0.0 3.2 4 0 0 4 4 4 0 zinc-finger Ribosomal_L36e PF01158.13 EPY54015.1 - 8.7e-40 134.6 3.7 9.4e-40 134.5 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.1 EPY54015.1 - 0.055 13.2 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator, TetR, C-terminal LemA PF04011.7 EPY54015.1 - 0.069 12.2 0.1 0.073 12.1 0.1 1.1 1 0 0 1 1 1 0 LemA family RNB PF00773.14 EPY54016.1 - 4.5e-46 157.6 0.7 9.1e-46 156.6 0.5 1.6 1 0 0 1 1 1 1 RNB domain DSPc PF00782.15 EPY54017.1 - 4.9e-07 29.3 0.0 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPY54017.1 - 7.4e-05 22.1 0.0 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EPY54017.1 - 0.00027 21.0 0.1 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EPY54017.1 - 0.00053 20.2 0.1 0.00095 19.4 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family WD40 PF00400.27 EPY54018.1 - 3.3e-24 83.8 5.6 4.8e-06 26.2 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat SSrecog PF03531.9 EPY54019.1 - 3e-98 327.5 0.0 4.5e-98 327.0 0.0 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EPY54019.1 - 4.4e-29 100.3 0.0 2.2e-25 88.4 0.0 2.9 3 0 0 3 3 3 2 Histone chaperone Rttp106-like Ribosomal_L29e PF01779.12 EPY54020.1 - 8.9e-22 76.6 14.8 1.3e-21 76.1 10.2 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Metallophos PF00149.23 EPY54021.1 - 1.2e-43 148.8 0.7 1.5e-43 148.5 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homoserine_dh PF00742.14 EPY54022.1 - 1.5e-51 174.6 0.0 2.3e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EPY54022.1 - 1.8e-17 63.8 0.0 4.2e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPY54022.1 - 0.041 13.0 0.1 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sec23_trunk PF04811.10 EPY54023.1 - 3.9e-70 235.9 0.0 5.5e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPY54023.1 - 1.3e-30 104.9 0.2 2.6e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPY54023.1 - 9.7e-29 99.7 0.0 2.5e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPY54023.1 - 1.8e-15 56.2 9.0 3.8e-15 55.1 6.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPY54023.1 - 2.8e-12 46.1 0.0 7.9e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat DUF2838 PF10998.3 EPY54024.1 - 1.3e-37 128.0 10.9 1.3e-37 128.0 7.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 EPY54024.1 - 0.021 13.7 1.3 0.038 12.9 0.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2317 PF10079.4 EPY54024.1 - 0.077 11.5 0.3 0.66 8.5 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) SPASM PF13186.1 EPY54024.1 - 0.13 12.6 0.5 0.49 10.7 0.1 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Pox_A_type_inc PF04508.7 EPY54024.1 - 4.1 7.4 5.8 9.1 6.3 0.1 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat SPA PF08616.5 EPY54025.1 - 2.5e-31 107.6 0.0 6e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EPY54025.1 - 3.1e-24 85.6 0.0 5.5e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.4 EPY54025.1 - 1.1e-06 27.3 5.0 0.0015 17.0 0.0 3.2 2 1 1 3 3 3 3 Transport protein Avl9 MAM33 PF02330.11 EPY54026.1 - 1.1e-54 185.2 2.7 1.3e-54 185.0 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Nrap PF03813.9 EPY54027.1 - 2.7e-273 909.0 1.5 3.3e-273 908.7 1.1 1.0 1 0 0 1 1 1 1 Nrap protein DEAD PF00270.24 EPY54028.1 - 1.3e-40 138.6 0.0 1.9e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY54028.1 - 4e-23 81.0 0.1 8.4e-23 80.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EPY54028.1 - 0.056 12.5 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 EPY54028.1 - 0.2 11.4 0.7 0.4 10.4 0.2 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain COG6 PF06419.6 EPY54029.1 - 9.7e-124 413.7 14.6 1.2e-123 413.4 10.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Apo-CII PF05355.6 EPY54029.1 - 0.12 12.2 0.8 6.5 6.6 0.1 2.7 2 0 0 2 2 2 0 Apolipoprotein C-II TPR_15 PF13429.1 EPY54029.1 - 0.16 11.0 1.9 0.15 11.1 0.4 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fib_alpha PF08702.5 EPY54029.1 - 0.2 11.7 1.3 1.4 9.0 0.3 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family zf-CHY PF05495.7 EPY54030.1 - 2.4e-15 56.4 11.7 3.4e-15 55.9 8.1 1.2 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C7 PF14522.1 EPY54030.1 - 0.044 13.4 8.1 0.1 12.2 5.6 1.7 1 1 0 1 1 1 0 Cytochrome c7 zf-C3HC4_3 PF13920.1 EPY54030.1 - 0.054 13.1 2.3 0.054 13.1 1.6 2.7 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Spt4 PF06093.8 EPY54030.1 - 0.21 11.4 5.4 5.8 6.8 2.1 2.4 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger RNA_pol_N PF01194.12 EPY54030.1 - 0.68 10.0 5.8 41 4.3 1.4 3.2 1 1 1 2 2 2 0 RNA polymerases N / 8 kDa subunit DZR PF12773.2 EPY54030.1 - 0.89 9.4 15.5 1.2e+02 2.5 10.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 EPY54030.1 - 1.8 8.3 14.7 0.25 11.1 1.6 2.7 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mut7-C PF01927.11 EPY54030.1 - 2.8 7.9 6.9 7.6 6.4 4.9 1.6 1 1 0 1 1 1 0 Mut7-C RNAse domain DUF1451 PF07295.6 EPY54030.1 - 3.7 7.3 7.2 0.87 9.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) OrfB_Zn_ribbon PF07282.6 EPY54030.1 - 9.6 5.9 10.9 1.3 8.7 1.2 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain GFA PF04828.9 EPY54031.1 - 7.7e-11 41.7 6.3 1.3e-10 41.1 4.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EPY54031.1 - 0.078 12.8 0.4 0.078 12.8 0.3 2.2 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_L18e PF00828.14 EPY54032.1 - 2.4e-34 118.4 0.1 2.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EPY54033.1 - 7.8e-42 143.2 0.0 4e-40 137.5 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54033.1 - 5.8e-11 41.9 0.1 3.6e-07 29.5 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EPY54033.1 - 4.2e-05 23.3 0.0 0.0017 18.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family MecA PF05389.7 EPY54033.1 - 1.8 8.0 12.3 0.031 13.7 3.4 1.8 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Cnd1 PF12717.2 EPY54034.1 - 1.8e-51 174.4 8.2 1.9e-48 164.6 0.6 4.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EPY54034.1 - 1.4e-33 115.9 10.8 1.5e-33 115.8 3.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EPY54034.1 - 4.2e-10 39.7 0.4 0.00092 19.4 0.1 3.6 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 EPY54034.1 - 1.4e-06 27.8 1.7 1.2 9.3 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EPY54034.1 - 0.0013 19.1 0.2 7.6 7.1 0.0 4.7 3 1 1 4 4 4 1 HEAT-like repeat LCAT PF02450.10 EPY54035.1 - 1.2e-130 435.9 0.0 1.5e-130 435.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EPY54035.1 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) 2-oxoacid_dh PF00198.18 EPY54036.1 - 5e-77 258.2 0.0 6.2e-77 257.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPY54036.1 - 4e-18 64.8 0.1 6.8e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EPY54036.1 - 0.00026 20.5 0.2 0.1 12.2 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.2 EPY54036.1 - 0.0024 17.0 0.0 0.36 9.9 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 EPY54036.1 - 0.0033 17.0 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EPY54036.1 - 0.012 15.2 0.0 0.19 11.4 0.0 2.3 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 EPY54036.1 - 0.022 15.1 0.1 5.7 7.3 0.0 2.4 2 0 0 2 2 2 0 HlyD family secretion protein HEAT PF02985.17 EPY54037.1 - 0.00028 20.7 0.5 2.1 8.6 0.0 3.4 3 0 0 3 3 3 2 HEAT repeat DAGK_prokar PF01219.14 EPY54037.1 - 0.033 13.7 8.1 1.2 8.7 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase FixP_N PF14715.1 EPY54037.1 - 0.22 10.9 8.9 2.2 7.7 0.3 3.1 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP SFTA2 PF15210.1 EPY54037.1 - 0.42 10.2 3.3 18 4.9 0.1 2.7 2 0 0 2 2 2 0 Surfactant-associated protein 2 DUF4282 PF14110.1 EPY54037.1 - 0.91 9.7 12.3 3.2 8.0 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) COX4_pro_2 PF07835.7 EPY54037.1 - 3.4 7.7 4.6 35 4.4 0.3 2.5 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV HSP20 PF00011.16 EPY54038.1 - 1e-21 76.7 0.4 1.2e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EPY54038.1 - 0.024 15.1 0.2 0.058 13.9 0.0 1.7 2 0 0 2 2 2 0 CS domain DUF4097 PF13349.1 EPY54038.1 - 0.042 13.4 0.1 0.065 12.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) FA_desaturase PF00487.19 EPY54039.1 - 0.0095 15.4 4.2 0.013 14.9 2.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase CRPA PF05745.6 EPY54039.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF1129 PF06570.6 EPY54039.1 - 0.074 12.3 2.3 0.11 11.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Herpes_LMP1 PF05297.6 EPY54039.1 - 0.12 11.2 0.4 0.16 10.8 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF373 PF04123.8 EPY54039.1 - 0.27 10.2 2.1 0.37 9.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2207 PF09972.4 EPY54039.1 - 0.34 9.4 3.8 0.42 9.1 2.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2244 PF10003.4 EPY54039.1 - 2.1 7.6 5.6 4.3 6.6 3.9 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Nop PF01798.13 EPY54040.1 - 1.1e-56 190.3 1.9 2.2e-56 189.3 1.3 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPY54040.1 - 5.5e-28 96.5 0.0 9.9e-28 95.7 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPY54040.1 - 1.4e-20 73.2 1.5 1.4e-20 73.2 1.0 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain MIF4G_like PF09088.6 EPY54040.1 - 0.12 11.7 0.0 11 5.3 0.0 2.9 2 1 0 3 3 3 0 MIF4G like GAGA_bind PF06217.7 EPY54040.1 - 0.69 9.8 12.6 1 9.2 8.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4604 PF15377.1 EPY54040.1 - 1.6 8.9 37.0 2.8 8.1 25.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RGS PF00615.14 EPY54041.1 - 7.2e-06 26.1 1.7 8e-06 25.9 0.4 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain INO80_Ies4 PF08193.6 EPY54042.1 - 7.5e-33 114.3 13.8 1.3e-32 113.5 9.6 1.4 1 1 0 1 1 1 1 INO80 complex subunit Ies4 K_oxygenase PF13434.1 EPY54043.1 - 7.1e-99 330.9 0.1 8.5e-99 330.7 0.1 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPY54043.1 - 1.5e-11 44.2 0.1 8.7e-10 38.5 0.0 2.6 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPY54043.1 - 6.3e-10 39.4 0.0 9.6e-07 29.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPY54043.1 - 3e-05 23.9 0.0 0.017 15.0 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FtsA PF14450.1 EPY54043.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsA AMP-binding PF00501.23 EPY54044.1 - 3.7e-174 579.0 0.0 5.8e-85 285.1 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EPY54044.1 - 1.1e-172 572.8 6.3 2e-36 125.4 0.1 8.0 7 1 0 7 7 7 6 Condensation domain PP-binding PF00550.20 EPY54044.1 - 3.8e-36 123.1 8.3 1.5e-08 34.7 0.0 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPY54044.1 - 6.5e-08 33.4 0.0 0.014 16.3 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EPY54044.1 - 1.3 8.5 0.0 81 2.6 0.0 2.6 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RNA_pol_Rpb2_6 PF00562.23 EPY54045.1 - 1.6e-126 422.1 0.1 2.9e-126 421.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPY54045.1 - 2.1e-74 248.8 0.1 3.1e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPY54045.1 - 1.5e-52 177.7 0.2 3e-52 176.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EPY54045.1 - 2.4e-28 97.7 0.3 7.3e-28 96.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_7 PF04560.15 EPY54045.1 - 2.8e-27 94.7 0.0 7.1e-27 93.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EPY54045.1 - 4.5e-23 80.7 0.0 9.8e-23 79.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EPY54045.1 - 2e-22 78.8 0.6 4.9e-22 77.6 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_45 PF10385.4 EPY54045.1 - 0.13 12.0 0.3 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Ribosomal_S8e PF01201.17 EPY54046.1 - 2e-49 167.0 1.7 2.3e-49 166.8 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EPY54046.1 - 0.059 13.6 0.2 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 Small acidic protein family Na_Ca_ex PF01699.19 EPY54047.1 - 1.4e-26 92.7 34.7 9.3e-18 64.1 6.4 3.6 4 1 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EPY54047.1 - 2e-07 31.3 10.7 2e-07 31.3 7.4 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF307) Trypan_PARP PF05887.6 EPY54047.1 - 0.1 12.3 0.2 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) adh_short PF00106.20 EPY54048.1 - 6.6e-33 113.9 0.0 8.3e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY54048.1 - 1.5e-14 54.4 0.0 1.8e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPY54048.1 - 6.4e-12 45.4 0.0 8.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPY54048.1 - 0.00057 18.8 0.1 0.0014 17.5 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPY54048.1 - 0.017 14.8 0.1 0.034 13.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Spore_IV_A PF09547.5 EPY54048.1 - 0.084 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) WLM PF08325.5 EPY54049.1 - 1.7e-45 155.1 0.0 4.2e-45 153.9 0.0 1.6 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EPY54049.1 - 0.0003 20.6 0.1 0.0003 20.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EPY54049.1 - 0.00099 18.7 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Reprolysin_3 PF13582.1 EPY54049.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Methyltransf_15 PF09445.5 EPY54050.1 - 4.7e-46 156.3 0.0 6e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EPY54050.1 - 4e-07 30.0 0.0 8e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPY54050.1 - 0.00018 21.2 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EPY54050.1 - 0.0018 18.8 0.0 0.0026 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EPY54050.1 - 0.002 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase DUF3591 PF12157.3 EPY54051.1 - 1.8e-197 656.3 0.7 2.9e-197 655.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EPY54051.1 - 2.6e-05 23.7 1.6 5.9e-05 22.6 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EPY54051.1 - 0.0079 16.0 1.2 0.014 15.3 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle ATG22 PF11700.3 EPY54052.1 - 4.7e-94 315.5 21.4 5.8e-94 315.2 14.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DEAD PF00270.24 EPY54053.1 - 2.8e-21 75.7 0.0 2.3e-20 72.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY54053.1 - 2.5e-20 72.1 0.0 5.6e-18 64.5 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EPY54053.1 - 2e-19 69.2 0.0 5e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EPY54053.1 - 3.8e-12 45.7 0.0 8.8e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain GPP34 PF05719.6 EPY54053.1 - 0.084 12.9 0.1 1.2 9.2 0.0 2.6 3 0 0 3 3 3 0 Golgi phosphoprotein 3 (GPP34) HA2 PF04408.18 EPY54054.1 - 2.2e-22 79.0 0.1 2.2e-22 79.0 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPY54054.1 - 8.3e-22 77.1 0.0 1.8e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPY54054.1 - 5.6e-15 54.9 0.0 2.7e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY54054.1 - 3.2e-07 30.0 0.0 8.9e-07 28.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPY54054.1 - 4.7e-06 26.7 0.0 1.6e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPY54054.1 - 0.00033 20.9 0.1 0.013 15.7 0.0 2.8 1 1 1 2 2 2 1 ABC transporter T2SE PF00437.15 EPY54054.1 - 0.00058 18.8 0.0 0.0014 17.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EPY54054.1 - 0.0019 17.3 0.1 0.0052 15.9 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_14 PF13173.1 EPY54054.1 - 0.0028 17.5 0.0 0.028 14.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPY54054.1 - 0.0045 16.1 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 EPY54054.1 - 0.01 15.5 0.0 0.052 13.2 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase ResIII PF04851.10 EPY54054.1 - 0.012 15.4 0.2 6.5 6.5 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EPY54054.1 - 0.012 15.1 0.0 0.031 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EPY54054.1 - 0.019 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EPY54054.1 - 0.02 14.8 0.1 0.14 12.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.1 EPY54054.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2738 PF10927.3 EPY54054.1 - 0.09 11.8 1.7 0.13 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2738) AAA_33 PF13671.1 EPY54054.1 - 0.1 12.4 0.2 0.33 10.8 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EPY54054.1 - 0.18 12.1 0.2 0.18 12.1 0.1 2.8 2 1 1 3 3 2 0 AAA domain ThiF PF00899.16 EPY54055.1 - 1.9e-40 137.8 0.0 4.7e-40 136.5 0.0 1.6 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EPY54055.1 - 1.5e-28 98.1 0.2 2.7e-28 97.3 0.2 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EPY54055.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain ELFV_dehydrog PF00208.16 EPY54055.1 - 0.016 14.8 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 EPY54055.1 - 0.042 13.9 0.1 1.4 9.0 0.1 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF221 PF02714.10 EPY54056.1 - 5e-97 324.6 21.6 5e-97 324.6 15.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPY54056.1 - 2.3e-32 111.7 3.4 2.3e-32 111.7 2.4 3.4 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPY54056.1 - 1.2e-11 44.9 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EPY54056.1 - 0.00016 21.5 0.0 0.025 14.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPY54056.1 - 0.0027 17.2 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF746 PF05344.6 EPY54056.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) SMN PF06003.7 EPY54057.1 - 9.2e-05 21.6 17.9 0.14 11.2 0.9 2.8 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Ycf1 PF05758.7 EPY54057.1 - 0.064 10.9 3.5 0.068 10.8 2.4 1.0 1 0 0 1 1 1 0 Ycf1 Spore_III_AB PF09548.5 EPY54057.1 - 0.1 12.3 7.6 0.15 11.8 5.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CDC45 PF02724.9 EPY54057.1 - 0.12 10.3 3.6 0.11 10.5 2.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Rib_recp_KP_reg PF05104.7 EPY54057.1 - 1.5 9.3 9.0 2.1 8.8 6.3 1.1 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Nop14 PF04147.7 EPY54057.1 - 1.8 6.3 11.2 2.1 6.1 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 EPY54057.1 - 3.2 8.1 7.8 6.1 7.2 5.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PP2C PF00481.16 EPY54058.1 - 7.3e-85 284.4 0.0 9.4e-85 284.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPY54058.1 - 0.00014 21.3 0.0 0.0004 19.8 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPY54058.1 - 0.025 14.3 0.1 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) AAA PF00004.24 EPY54059.1 - 2.1e-45 154.1 0.0 5.1e-45 152.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPY54059.1 - 2.5e-27 94.5 0.1 2e-26 91.6 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EPY54059.1 - 9.3e-22 76.6 2.3 2.5e-21 75.3 1.5 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EPY54059.1 - 3.8e-06 27.7 0.0 1.1e-05 26.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EPY54059.1 - 4.5e-06 26.8 0.6 0.0012 18.9 0.1 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EPY54059.1 - 9.4e-06 24.8 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPY54059.1 - 2.4e-05 24.2 0.0 9.6e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPY54059.1 - 3.2e-05 23.4 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EPY54059.1 - 5.4e-05 22.9 0.0 0.00024 20.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPY54059.1 - 5.8e-05 23.1 0.1 0.0012 18.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EPY54059.1 - 0.00011 21.6 0.1 0.15 11.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 EPY54059.1 - 0.00023 21.0 0.0 0.00049 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPY54059.1 - 0.00027 19.8 0.0 0.00053 18.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EPY54059.1 - 0.00052 19.0 0.0 0.00092 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EPY54059.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EPY54059.1 - 0.0025 17.9 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 EPY54059.1 - 0.0055 16.9 0.1 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPY54059.1 - 0.0067 15.5 0.1 0.18 10.8 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EPY54059.1 - 0.0067 16.0 0.1 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF1495 PF07381.6 EPY54059.1 - 0.0084 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) Arch_ATPase PF01637.13 EPY54059.1 - 0.022 14.4 0.3 0.61 9.7 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 EPY54059.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EPY54059.1 - 0.025 14.2 0.0 0.69 9.5 0.0 2.3 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 EPY54059.1 - 0.033 13.4 0.0 0.078 12.2 0.0 1.7 2 0 0 2 2 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EPY54059.1 - 0.034 13.0 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 EPY54059.1 - 0.037 13.1 0.1 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EPY54059.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EPY54059.1 - 0.048 13.1 0.0 0.68 9.3 0.0 2.6 1 1 2 3 3 3 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EPY54059.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family KaiC PF06745.8 EPY54059.1 - 0.083 11.9 0.1 9.7 5.2 0.0 2.3 1 1 1 2 2 2 0 KaiC Torsin PF06309.6 EPY54059.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Peptidase_M28 PF04389.12 EPY54059.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 AAA_21 PF13304.1 EPY54059.1 - 0.13 12.1 2.9 2.5 7.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 EPY54059.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain BRO1 PF03097.13 EPY54060.1 - 1.1e-51 175.7 4.1 2.6e-51 174.5 2.9 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPY54060.1 - 5.6e-24 84.6 12.4 5.6e-24 84.6 8.6 1.9 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF4413 PF14372.1 EPY54060.1 - 0.0028 17.6 0.5 0.012 15.6 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) CobU PF02283.11 EPY54060.1 - 0.006 16.0 0.1 0.015 14.6 0.1 1.7 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase GrpE PF01025.14 EPY54060.1 - 0.21 11.1 3.3 9.6 5.7 0.0 3.7 4 0 0 4 4 4 0 GrpE G-patch PF01585.18 EPY54061.1 - 3.5e-11 42.7 0.3 8.1e-11 41.5 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPY54061.1 - 3e-06 26.9 0.1 1.7e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site Sec1 PF00995.18 EPY54062.1 - 8.8e-147 490.1 4.3 1e-146 489.9 3.0 1.0 1 0 0 1 1 1 1 Sec1 family Urb2 PF10441.4 EPY54063.1 - 4.4e-39 134.3 13.2 8e-39 133.5 3.1 3.3 2 1 0 2 2 2 2 Urb2/Npa2 family Pkinase PF00069.20 EPY54064.1 - 2.1e-57 194.2 0.0 3.7e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54064.1 - 2.9e-24 85.5 0.0 3.8e-23 81.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY54064.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family UPF1_Zn_bind PF09416.5 EPY54065.1 - 8e-72 239.8 4.4 1.8e-71 238.6 3.0 1.6 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EPY54065.1 - 9.4e-59 198.1 0.0 2.1e-58 197.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPY54065.1 - 8.8e-55 185.8 1.0 1.5e-54 185.0 0.7 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPY54065.1 - 7.4e-15 54.4 0.1 2.4e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPY54065.1 - 9.6e-15 54.6 0.1 1.9e-13 50.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EPY54065.1 - 1.2e-06 28.5 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EPY54065.1 - 1.2e-05 24.7 0.0 0.0036 16.6 0.0 2.5 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EPY54065.1 - 0.00024 20.7 0.0 0.12 11.8 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EPY54065.1 - 0.00029 19.9 4.3 0.00039 19.5 0.0 3.0 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EPY54065.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EPY54065.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DEAD PF00270.24 EPY54065.1 - 0.022 14.2 0.0 0.05 13.1 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 EPY54065.1 - 0.025 13.7 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.9 EPY54065.1 - 0.03 14.0 0.0 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PIF1 PF05970.9 EPY54065.1 - 0.059 12.3 0.0 0.68 8.8 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase Helicase_RecD PF05127.9 EPY54065.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 EPY54065.1 - 0.11 12.6 0.0 0.36 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EPY54065.1 - 0.17 12.1 0.2 0.37 10.9 0.2 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EPY54065.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PHD PF00628.24 EPY54066.1 - 4e-12 45.6 25.1 7.1e-12 44.8 3.9 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 EPY54066.1 - 1.1e-05 25.4 12.5 0.0042 17.1 1.7 2.4 2 0 0 2 2 2 2 PHD-like zinc-binding domain C1_1 PF00130.17 EPY54066.1 - 0.00012 21.7 24.0 0.0029 17.2 7.3 3.5 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 EPY54066.1 - 0.062 13.2 15.3 0.052 13.5 1.4 2.5 2 1 0 2 2 2 0 PHD-zinc-finger like domain zf-PHD-like PF15446.1 EPY54066.1 - 1.1 8.5 11.4 2.9 7.1 0.1 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_4 PF14570.1 EPY54067.1 - 7e-21 73.5 12.3 7e-21 73.5 8.5 1.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EPY54067.1 - 2e-06 27.3 0.0 5e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY54067.1 - 1.8e-05 24.5 0.0 4.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 EPY54067.1 - 0.00041 20.0 2.4 0.00041 20.0 1.7 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger Rtf2 PF04641.7 EPY54067.1 - 0.0045 16.2 2.1 0.0072 15.5 1.5 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 EPY54067.1 - 0.0053 16.7 12.3 0.0053 16.7 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EPY54067.1 - 0.067 13.1 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EPY54067.1 - 0.11 12.2 6.3 0.069 12.8 2.7 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) NMD3 PF04981.8 EPY54068.1 - 9e-75 250.8 5.6 1.2e-74 250.4 3.9 1.2 1 0 0 1 1 1 1 NMD3 family RbsD_FucU PF05025.8 EPY54068.1 - 0.067 13.5 0.1 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 RbsD / FucU transport protein family PNP_UDP_1 PF01048.15 EPY54069.1 - 1.5e-31 109.2 0.0 1.7e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF3227 PF11537.3 EPY54069.1 - 0.053 13.6 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) PfkB PF00294.19 EPY54070.1 - 1.5e-11 43.9 0.0 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-C2H2 PF00096.21 EPY54071.1 - 4.5e-14 51.8 18.5 3.3e-06 27.0 1.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPY54071.1 - 5.3e-10 39.0 17.4 9.3e-07 28.8 0.4 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPY54071.1 - 7.8e-10 38.3 15.3 0.00059 19.9 0.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPY54071.1 - 7.5e-05 22.7 7.0 0.097 12.8 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPY54071.1 - 0.00037 20.5 8.6 1.2 9.4 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Tmpp129 PF10272.4 EPY54071.1 - 0.038 12.7 1.4 0.062 12.0 1.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C2H2_6 PF13912.1 EPY54071.1 - 0.089 12.7 7.6 2.2 8.2 0.4 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPY54071.1 - 0.26 11.4 5.4 8.1 6.6 0.2 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.11 EPY54071.1 - 8.7 6.3 8.7 2.2 8.1 1.5 2.6 1 1 1 2 2 2 0 AN1-like Zinc finger Glyco_transf_22 PF03901.12 EPY54072.1 - 7e-65 219.6 40.0 8.6e-65 219.3 27.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EPY54072.1 - 0.00063 19.6 28.0 0.097 12.5 3.8 2.5 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase V-SNARE_C PF12352.3 EPY54073.1 - 1.3e-17 63.5 1.5 7e-17 61.2 0.4 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus FEZ PF07763.8 EPY54073.1 - 0.0013 18.5 4.6 0.0017 18.1 3.2 1.1 1 0 0 1 1 1 1 FEZ-like protein BMFP PF04380.8 EPY54073.1 - 0.035 14.2 0.8 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 Membrane fusogenic activity DUF3055 PF11256.3 EPY54073.1 - 0.052 13.6 0.1 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3055) Cluap1 PF10234.4 EPY54073.1 - 0.062 12.4 4.0 0.084 12.0 2.7 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4570 PF15134.1 EPY54073.1 - 0.063 13.1 5.6 0.05 13.4 2.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) TAT_ubiq PF07706.7 EPY54073.1 - 0.081 12.8 0.6 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 Aminotransferase ubiquitination site PMC2NT PF08066.7 EPY54073.1 - 0.091 13.0 4.4 6.6 7.1 0.0 2.5 2 1 0 2 2 2 0 PMC2NT (NUC016) domain 7TMR-HDED PF07697.6 EPY54073.1 - 0.11 12.2 6.0 0.39 10.4 1.3 2.1 1 1 1 2 2 2 0 7TM-HD extracellular Spectrin PF00435.16 EPY54073.1 - 0.38 11.0 8.2 0.28 11.4 3.1 2.1 2 0 0 2 2 2 0 Spectrin repeat Poty_PP PF08440.5 EPY54073.1 - 0.71 8.8 4.1 0.69 8.9 0.2 2.0 1 1 1 2 2 2 0 Potyviridae polyprotein ATP-synt_10 PF05176.9 EPY54074.1 - 1.7e-48 165.0 0.1 2.5e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein tRNA-synt_1 PF00133.17 EPY54075.1 - 5.5e-57 193.1 1.6 1.4e-35 122.4 3.1 6.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EPY54075.1 - 9.8e-39 132.5 0.1 3.6e-38 130.7 0.1 1.9 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EPY54075.1 - 3.2e-28 98.4 1.0 2.7e-22 78.9 0.9 4.3 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPY54075.1 - 3.9e-13 49.4 0.0 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EPY54075.1 - 0.0012 17.7 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EPY54075.1 - 0.011 14.8 0.0 0.059 12.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain EST1 PF10374.4 EPY54075.1 - 0.037 14.0 0.2 0.093 12.7 0.2 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 Mito_carr PF00153.22 EPY54076.1 - 2e-38 129.9 6.4 1.9e-17 62.7 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DDE_1 PF03184.14 EPY54077.1 - 3.8e-50 170.0 1.1 1.4e-49 168.2 0.2 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPY54077.1 - 1.7e-16 59.7 2.2 3.5e-16 58.7 0.8 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Pkinase PF00069.20 EPY54078.1 - 7e-68 228.5 0.0 1.4e-67 227.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54078.1 - 9.6e-29 100.2 0.1 9e-28 97.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY54078.1 - 1.8e-06 27.1 0.1 0.064 12.1 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EPY54078.1 - 0.041 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RabGAP-TBC PF00566.13 EPY54079.1 - 1.1e-47 162.3 0.0 1.9e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PUF PF00806.14 EPY54080.1 - 1.7e-56 184.5 8.4 9.9e-08 31.0 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SecE PF00584.15 EPY54081.1 - 7.9e-12 44.5 0.1 8.7e-12 44.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Fip1 PF05182.8 EPY54082.1 - 1.1e-25 88.5 0.8 2.2e-25 87.6 0.5 1.5 1 0 0 1 1 1 1 Fip1 motif Con-6 PF10346.4 EPY54083.1 - 2e-17 62.2 0.1 3.7e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 SpoIIIAH PF12685.2 EPY54083.1 - 0.03 13.8 0.2 0.063 12.7 0.1 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Nucleoporin_FG PF13634.1 EPY54084.1 - 4.3e-19 68.8 108.1 8.2e-10 38.9 28.4 3.5 1 1 2 3 3 3 3 Nucleoporin FG repeat region ArsR PF09824.4 EPY54084.1 - 0.041 13.2 0.1 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 ArsR transcriptional regulator Pkinase PF00069.20 EPY54085.1 - 5.6e-54 183.0 0.0 7.6e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54085.1 - 9.8e-18 64.1 0.0 1.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY54085.1 - 0.0016 18.1 0.2 0.0063 16.2 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY54085.1 - 0.12 11.3 0.0 0.32 9.9 0.0 1.7 1 1 0 1 1 1 0 Kinase-like MT-A70 PF05063.9 EPY54086.1 - 1.7e-37 128.6 1.9 2.6e-37 128.0 1.3 1.3 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EPY54086.1 - 0.075 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAR1 PF03101.10 EPY54086.1 - 0.098 13.1 1.8 0.12 12.8 0.5 1.7 2 0 0 2 2 2 0 FAR1 DNA-binding domain CPSase_L_D2 PF02786.12 EPY54087.1 - 1.4e-113 377.3 0.2 1.3e-84 282.7 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EPY54087.1 - 1.5e-47 160.3 0.0 4e-47 158.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EPY54087.1 - 2e-43 148.0 0.0 4.2e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 EPY54087.1 - 5.4e-42 142.3 0.0 2.7e-20 72.4 0.0 3.2 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace_N PF02729.16 EPY54087.1 - 1.3e-39 135.0 0.0 3e-39 133.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EPY54087.1 - 1.8e-39 134.2 0.1 3.6e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 EPY54087.1 - 2.1e-37 128.4 0.1 1.4e-36 125.7 0.0 2.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EPY54087.1 - 1.1e-34 119.7 0.1 1.4e-20 73.8 0.0 3.6 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPY54087.1 - 3e-23 82.0 0.1 1.6e-11 43.5 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EPY54087.1 - 9.5e-19 67.1 0.0 4.3e-18 65.0 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EPY54087.1 - 1.8e-17 63.3 0.8 7.9e-09 35.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPY54087.1 - 2.6e-15 56.1 0.1 6.7e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EPY54087.1 - 9.3e-07 28.8 0.4 0.011 15.5 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EPY54087.1 - 2.5e-05 23.8 0.1 0.0041 16.5 0.0 3.0 2 1 0 2 2 2 1 Peptidase C26 RimK PF08443.6 EPY54087.1 - 0.00021 20.7 0.0 0.031 13.7 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_C PF02843.11 EPY54087.1 - 0.067 13.3 0.0 8.2 6.6 0.0 2.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Kri1_C PF12936.2 EPY54088.1 - 4.1e-28 97.1 0.5 4.1e-28 97.1 0.4 5.0 6 1 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 EPY54088.1 - 2.1e-26 92.1 14.8 2.1e-26 92.1 10.3 5.6 5 1 1 6 6 6 1 KRI1-like family UCH_1 PF13423.1 EPY54089.1 - 3.7e-47 161.1 0.1 5.3e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EPY54089.1 - 9.4e-30 104.0 0.0 1.7e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EPY54089.1 - 1.1e-05 24.6 0.0 6.1e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EPY54089.1 - 0.0087 15.9 0.8 1.7 8.6 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat IBN_N PF03810.14 EPY54091.1 - 0.02 14.7 0.3 0.084 12.8 0.2 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain Peptidase_M24 PF00557.19 EPY54092.1 - 9.1e-42 142.9 0.0 1.4e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EPY54092.1 - 8.2e-24 84.5 0.1 3e-18 66.5 0.0 2.7 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain DUF500 PF04366.7 EPY54093.1 - 1.1e-43 147.6 0.2 1.6e-43 147.1 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EPY54093.1 - 1e-14 53.6 0.0 2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPY54093.1 - 1.1e-11 44.0 0.0 1.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPY54093.1 - 1.4e-11 43.7 0.0 2.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PX PF00787.19 EPY54094.1 - 2.4e-09 36.9 0.0 6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EPY54094.1 - 1.2e-08 34.5 6.8 2e-08 33.8 4.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like FAD_binding_1 PF00667.15 EPY54095.1 - 3e-31 108.5 0.0 4.4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPY54095.1 - 1.3e-28 99.7 0.0 3.5e-28 98.3 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EPY54095.1 - 1.2e-16 61.2 0.0 4.5e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Adenine_deam_C PF13382.1 EPY54095.1 - 0.26 10.4 0.0 0.43 9.7 0.0 1.2 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain SNF2_N PF00176.18 EPY54096.1 - 2.9e-56 190.4 1.2 4.6e-56 189.7 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY54096.1 - 1.3e-10 40.9 0.0 6e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY54096.1 - 1e-06 28.3 0.0 2.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPY54096.1 - 2e-06 27.7 0.3 2.7e-05 24.0 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EPY54096.1 - 0.024 13.6 0.0 0.051 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) bZIP_1 PF00170.16 EPY54097.1 - 2.9e-13 49.5 7.7 5.4e-13 48.6 5.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPY54097.1 - 9.3e-09 34.9 7.9 1.7e-08 34.1 5.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 EPY54097.1 - 0.0035 16.3 2.2 0.0047 15.9 1.5 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region HALZ PF02183.13 EPY54097.1 - 0.019 14.6 0.2 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper NTR PF01759.16 EPY54097.1 - 0.026 14.0 0.9 0.054 13.0 0.6 1.5 1 1 0 1 1 1 0 UNC-6/NTR/C345C module bZIP_Maf PF03131.12 EPY54097.1 - 0.041 14.1 5.3 0.083 13.1 3.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor PGM_PMM_I PF02878.11 EPY54098.1 - 9.1e-12 44.6 0.2 4.3e-07 29.4 0.0 2.8 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EPY54098.1 - 5.9e-10 39.4 0.0 2.7e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EPY54098.1 - 6.3e-10 38.9 0.1 1.3e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain COX5B PF01215.14 EPY54099.1 - 3.4e-54 182.1 0.0 4.2e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb ADK_lid PF05191.9 EPY54099.1 - 0.065 12.9 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-ISL3 PF14690.1 EPY54099.1 - 0.087 12.8 1.0 0.17 11.9 0.7 1.5 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Peptidase_S10 PF00450.17 EPY54100.1 - 5.4e-77 259.6 1.0 7.1e-77 259.3 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 EPY54101.1 - 5.4e-77 259.6 1.0 7.1e-77 259.3 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Pex24p PF06398.6 EPY54102.1 - 1e-05 24.5 3.9 1e-05 24.5 2.7 1.9 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin DNA_ligase_A_N PF04675.9 EPY54102.1 - 0.026 14.3 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 DNA ligase N terminus Cyclin_N PF00134.18 EPY54103.1 - 1e-09 38.0 0.1 8.6e-08 31.8 0.1 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPY54103.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain Pkinase PF00069.20 EPY54106.1 - 4.6e-48 163.6 0.0 6.3e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54106.1 - 2.2e-27 95.7 0.0 3.1e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY54106.1 - 0.00016 21.4 0.0 0.035 13.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY54106.1 - 0.00069 18.6 0.0 0.0024 16.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPY54106.1 - 0.0031 16.6 0.0 0.0076 15.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cation_efflux PF01545.16 EPY54107.1 - 5.9e-24 84.6 13.2 7.9e-24 84.2 9.1 1.1 1 0 0 1 1 1 1 Cation efflux family Wzy_C PF04932.10 EPY54107.1 - 0.018 14.8 1.7 0.079 12.7 1.2 1.9 1 1 0 1 1 1 0 O-Antigen ligase Pex24p PF06398.6 EPY54107.1 - 1.7 7.3 11.2 7.5 5.2 7.7 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin HSBP1 PF06825.7 EPY54108.1 - 2.5e-07 30.1 0.9 3.7e-07 29.6 0.6 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EPY54108.1 - 0.0066 15.7 0.4 0.083 12.2 0.2 2.2 1 1 1 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 EPY54108.1 - 0.041 13.7 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2217 PF10265.4 EPY54108.1 - 0.074 11.8 0.1 0.072 11.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PS_Dcarbxylase PF02666.10 EPY54110.1 - 5e-77 257.7 0.0 6.5e-75 250.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Cyclin_N PF00134.18 EPY54111.1 - 2.3e-26 91.8 0.0 6.1e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPY54111.1 - 1.7e-18 66.6 2.5 1.3e-17 63.8 0.2 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain ubiquitin PF00240.18 EPY54112.1 - 8.7e-11 41.0 0.1 1.5e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EPY54112.1 - 0.00047 20.0 0.1 0.0012 18.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPY54112.1 - 0.00087 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EPY54112.1 - 0.0079 15.8 1.2 0.013 15.1 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GPI-anchored PF10342.4 EPY54114.1 - 2.6e-16 59.8 3.6 2.6e-16 59.8 2.5 2.6 2 1 1 4 4 4 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Flg_bb_rod PF00460.15 EPY54114.1 - 0.0091 15.6 0.5 0.08 12.6 0.0 2.5 2 0 0 2 2 2 1 Flagella basal body rod protein DUF605 PF04652.11 EPY54114.1 - 0.11 11.9 14.8 0.12 11.7 10.3 1.1 1 0 0 1 1 1 0 Vta1 like Med3 PF11593.3 EPY54114.1 - 3.4 6.8 13.3 0.83 8.8 6.4 1.7 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal APC10 PF03256.11 EPY54115.1 - 2.4e-63 213.2 0.0 2.6e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EPY54115.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 F5/8 type C domain Iso_dh PF00180.15 EPY54116.1 - 7.5e-128 426.3 0.0 8.5e-128 426.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_topoisoIV PF00521.15 EPY54117.1 - 2.8e-125 418.5 0.0 4.4e-125 417.8 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EPY54117.1 - 5e-37 126.7 0.6 1.2e-36 125.5 0.4 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EPY54117.1 - 2.1e-13 50.0 0.0 7.2e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EPY54117.1 - 1.8e-09 37.3 0.0 6.3e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2247 PF10004.4 EPY54119.1 - 1.2 8.8 13.9 0.043 13.5 1.4 3.6 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2247) Mmp37 PF09139.6 EPY54120.1 - 3.4e-97 325.4 0.4 3.9e-97 325.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Sof1 PF04158.9 EPY54121.1 - 9e-31 105.7 13.6 1.6e-30 104.9 9.4 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 EPY54121.1 - 1.8e-30 103.6 13.9 2.1e-10 40.0 0.0 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EPY54121.1 - 3.9e-06 26.7 0.4 0.00053 19.7 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EPY54121.1 - 0.016 14.9 0.1 0.43 10.3 0.0 3.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Cpn60_TCP1 PF00118.19 EPY54122.1 - 9.1e-155 515.9 0.1 1e-154 515.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF148 PF02520.12 EPY54123.1 - 0.0012 18.6 1.2 0.091 12.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF148 BLOC1_2 PF10046.4 EPY54123.1 - 0.0064 16.6 0.9 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HbrB PF08539.6 EPY54123.1 - 0.071 12.9 0.3 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 HbrB-like Med21 PF11221.3 EPY54123.1 - 0.087 12.7 2.6 0.097 12.6 1.8 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex TruD PF01142.13 EPY54124.1 - 4.7e-66 222.9 0.0 6.3e-65 219.2 0.0 2.3 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) Med14 PF08638.6 EPY54125.1 - 3.2e-54 183.1 0.3 6.1e-54 182.2 0.2 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkr1 PF08636.5 EPY54126.1 - 8.6e-29 99.4 9.1 1e-28 99.1 6.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Wzy_C PF04932.10 EPY54126.1 - 0.0053 16.5 0.0 0.0068 16.1 0.0 1.1 1 0 0 1 1 1 1 O-Antigen ligase DUF4131 PF13567.1 EPY54126.1 - 0.0056 16.1 0.5 0.0065 15.9 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) YfhO PF09586.5 EPY54126.1 - 0.0085 14.1 0.2 0.0091 14.0 0.2 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO O-antigen_lig PF13425.1 EPY54126.1 - 0.012 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3357 PF11837.3 EPY54126.1 - 0.024 14.4 2.2 0.045 13.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) PAP2 PF01569.16 EPY54126.1 - 0.079 12.6 2.6 0.097 12.3 1.8 1.2 1 0 0 1 1 1 0 PAP2 superfamily PgaD PF13994.1 EPY54126.1 - 0.31 10.5 3.0 0.32 10.4 1.4 1.6 1 1 0 1 1 1 0 PgaD-like protein DUF2721 PF11026.3 EPY54126.1 - 0.83 9.2 7.0 1.4 8.5 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Cullin PF00888.17 EPY54127.1 - 5.7e-51 173.7 2.0 5.7e-51 173.7 1.4 2.4 2 1 0 2 2 2 1 Cullin family APC2 PF08672.6 EPY54127.1 - 2.8e-25 88.3 0.1 1e-24 86.5 0.1 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 SWI-SNF_Ssr4 PF08549.5 EPY54128.1 - 2.2e-28 98.9 2.0 2.6e-27 95.4 1.1 2.2 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) DUF327 PF03885.8 EPY54128.1 - 0.0099 15.7 0.8 0.016 15.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF327) Spc7 PF08317.6 EPY54128.1 - 0.013 14.1 1.7 0.02 13.5 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1002 PF06207.6 EPY54129.1 - 0.0075 15.6 2.1 0.0083 15.4 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1002) DUF2730 PF10805.3 EPY54129.1 - 0.039 13.6 4.9 0.049 13.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) CLAMP PF14769.1 EPY54129.1 - 0.12 12.5 4.8 2.3 8.4 0.2 2.1 1 1 1 2 2 2 0 Flagellar C1a complex subunit C1a-32 SNF5 PF04855.7 EPY54129.1 - 0.13 11.7 3.5 0.16 11.4 2.4 1.1 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 APG6 PF04111.7 EPY54129.1 - 0.4 9.6 10.1 0.47 9.4 7.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 EPY54129.1 - 0.58 10.4 5.6 0.69 10.1 3.9 1.1 1 0 0 1 1 1 0 AAA domain HTH_1 PF00126.22 EPY54129.1 - 1 9.1 3.7 0.96 9.2 1.1 2.0 2 1 1 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family IncA PF04156.9 EPY54129.1 - 2.9 7.4 12.5 9.3 5.7 8.7 1.7 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EPY54129.1 - 4.9 6.7 13.1 1.6 8.2 4.0 2.1 1 1 1 2 2 2 0 Septum formation initiator Mito_carr PF00153.22 EPY54130.1 - 4.5e-59 196.1 0.1 2.4e-19 68.8 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2109 PF09882.4 EPY54130.1 - 0.098 12.6 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) RNA_pol_Rpb2_6 PF00562.23 EPY54131.1 - 6.3e-112 374.1 0.1 8.9e-112 373.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPY54131.1 - 1.1e-39 135.5 0.1 1.5e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EPY54131.1 - 4.4e-24 84.0 0.0 1.3e-23 82.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EPY54131.1 - 6e-23 81.2 0.0 1.1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EPY54131.1 - 3e-21 75.1 0.0 7.4e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EPY54131.1 - 3.2e-15 56.1 0.2 1.2e-14 54.2 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EPY54131.1 - 5.1e-06 26.3 0.1 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 zf-Sec23_Sec24 PF04810.10 EPY54131.1 - 0.1 12.1 2.9 0.4 10.2 0.2 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Actin PF00022.14 EPY54132.1 - 6.3e-133 443.0 0.0 7.1e-133 442.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPY54132.1 - 0.00074 18.2 0.0 0.48 8.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FAM177 PF14774.1 EPY54132.1 - 0.011 15.6 2.1 0.019 14.8 1.5 1.3 1 0 0 1 1 1 0 FAM177 family DUF1134 PF06577.7 EPY54132.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) DUF2201_N PF13203.1 EPY54132.1 - 0.09 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Sld5 PF05916.6 EPY54133.1 - 5.6e-07 29.8 0.0 9.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Pkinase PF00069.20 EPY54134.1 - 1.3e-18 67.1 0.0 2.4e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54134.1 - 8.8e-11 41.3 0.0 2.3e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APG17 PF04108.7 EPY54134.1 - 0.0039 16.0 0.2 0.012 14.4 0.1 1.8 1 0 0 1 1 1 1 Autophagy protein Apg17 Ipi1_N PF12333.3 EPY54134.1 - 0.33 10.9 2.8 7 6.6 0.0 3.7 3 1 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF2401 PF10287.4 EPY54135.1 - 1.3e-96 322.6 4.1 2.8e-96 321.5 2.9 1.6 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EPY54135.1 - 4.4e-29 100.4 0.1 1.3e-28 98.9 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Pepsin-I3 PF06394.8 EPY54135.1 - 0.061 12.9 0.6 0.14 11.7 0.4 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain ELL PF10390.4 EPY54136.1 - 2.2e-24 86.1 0.8 2.2e-24 86.1 0.6 2.5 2 2 0 2 2 2 1 RNA polymerase II elongation factor ELL ORC4_C PF14629.1 EPY54137.1 - 1.8e-35 122.1 1.7 1.8e-35 122.1 1.2 1.7 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EPY54137.1 - 3e-13 50.1 0.2 1.6e-12 47.7 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain AT_hook PF02178.14 EPY54137.1 - 4.5e-06 25.7 68.4 0.021 14.4 2.0 7.0 6 0 0 6 6 6 6 AT hook motif AAA PF00004.24 EPY54137.1 - 0.00019 21.6 0.0 0.00084 19.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPY54137.1 - 0.00039 20.5 0.0 0.00099 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPY54137.1 - 0.00087 18.2 0.1 0.0018 17.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EPY54137.1 - 0.16 11.7 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family FRG1 PF06229.7 EPY54138.1 - 4.9e-22 78.3 1.4 9.7e-22 77.3 0.2 1.9 2 1 0 2 2 2 1 FRG1-like family Fascin PF06268.8 EPY54138.1 - 4.8e-06 26.6 0.1 1.7e-05 24.9 0.1 2.0 1 0 0 1 1 1 1 Fascin domain Peptidase_M16 PF00675.15 EPY54139.1 - 3.3e-52 176.2 3.2 3.5e-51 172.8 1.4 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPY54139.1 - 1.9e-40 138.5 0.0 5.1e-39 133.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.7 EPY54140.1 - 1.2e-52 176.9 0.0 1.5e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 CybS E1-E2_ATPase PF00122.15 EPY54141.1 - 7.2e-49 165.8 1.4 1.3e-48 165.1 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPY54141.1 - 4.3e-39 135.1 0.0 7.7e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPY54141.1 - 3.2e-10 40.4 0.0 8.7e-10 39.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EPY54141.1 - 3.2e-09 36.7 0.2 1.6e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain ELMO_CED12 PF04727.8 EPY54141.1 - 0.065 12.7 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 ELMO/CED-12 family MAGSP PF03082.9 EPY54141.1 - 0.076 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Male accessory gland secretory protein PRA-CH PF01502.13 EPY54142.1 - 1.5e-24 85.3 0.2 2.6e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EPY54142.1 - 4.5e-12 46.0 0.0 1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EPY54142.1 - 0.0041 17.0 0.1 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PrpR_N PF06506.6 EPY54142.1 - 0.11 11.8 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Propionate catabolism activator CLTH PF10607.4 EPY54143.1 - 1.5e-26 92.7 0.1 1.5e-26 92.7 0.1 2.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EPY54143.1 - 1.6e-17 62.9 0.9 1.6e-17 62.9 0.6 2.4 3 0 0 3 3 3 1 RING-type zinc-finger Rtf2 PF04641.7 EPY54143.1 - 6.2e-05 22.3 0.1 6.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EPY54143.1 - 0.00016 21.4 0.6 0.00016 21.4 0.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPY54143.1 - 0.0028 17.3 0.6 0.0028 17.3 0.4 2.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPY54143.1 - 0.008 16.0 0.8 0.037 13.9 0.6 2.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EPY54143.1 - 0.014 15.3 2.0 0.081 12.9 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPY54143.1 - 0.038 13.6 3.0 0.048 13.3 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.9 EPY54143.1 - 0.042 12.4 0.1 0.065 11.8 0.1 1.3 1 0 0 1 1 1 0 Pellino zf-C3HC4_3 PF13920.1 EPY54143.1 - 0.064 12.9 0.4 0.16 11.6 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AATF-Che1 PF13339.1 EPY54143.1 - 0.082 13.0 1.5 0.19 11.8 1.1 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF3128 PF11326.3 EPY54144.1 - 8.8e-23 80.2 3.2 1.3e-22 79.6 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) AlaDh_PNT_N PF05222.10 EPY54145.1 - 2.7e-27 95.4 0.0 3.6e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EPY54145.1 - 8e-18 64.5 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiC-associated PF13667.1 EPY54145.1 - 0.02 14.4 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 ThiC-associated domain NIF PF03031.13 EPY54146.1 - 4.8e-48 162.8 0.1 6.6e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Cys_rich_VLP PF14194.1 EPY54146.1 - 0.14 11.9 0.3 4.2 7.1 0.1 2.5 2 0 0 2 2 2 0 Cysteine-rich VLP Pkinase PF00069.20 EPY54147.1 - 9.3e-52 175.7 0.0 1.7e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54147.1 - 4e-15 55.5 0.2 1.3e-14 53.9 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPY54147.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EPY54147.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Med1 PF10744.4 EPY54148.1 - 1.1e-22 80.4 3.5 8.5e-22 77.4 2.4 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 eIF-5_eIF-2B PF01873.12 EPY54150.1 - 5.1e-45 152.1 0.1 8.5e-45 151.4 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EPY54150.1 - 1.6e-20 72.8 0.8 4.9e-20 71.2 0.5 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RNA_POL_M_15KD PF02150.11 EPY54150.1 - 0.38 10.4 2.5 1.1 9.0 1.8 1.8 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit DNA_pol_lambd_f PF10391.4 EPY54151.1 - 3.6e-20 71.2 0.7 6.3e-20 70.4 0.5 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EPY54151.1 - 4.6e-13 49.1 0.0 9.6e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 EPY54151.1 - 3.2e-11 42.7 0.0 8.8e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EPY54151.1 - 1.7e-07 31.3 0.0 2.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm PHD PF00628.24 EPY54152.1 - 4.3e-17 61.5 24.0 2.6e-11 43.0 6.3 2.5 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 EPY54152.1 - 0.016 14.9 3.9 0.016 14.9 2.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 EPY54152.1 - 0.017 15.2 2.4 0.017 15.2 1.7 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EPY54152.1 - 0.3 11.0 9.7 0.47 10.4 1.5 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain SNF5 PF04855.7 EPY54153.1 - 8.1e-74 248.1 0.1 1.2e-73 247.6 0.1 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 MMR_HSR1 PF01926.18 EPY54154.1 - 4e-06 26.7 0.0 9.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPY54154.1 - 0.008 16.1 0.0 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EPY54154.1 - 0.0082 16.6 0.2 0.031 14.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EPY54154.1 - 0.009 15.2 0.1 0.033 13.3 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPY54154.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPY54154.1 - 0.068 13.4 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EPY54154.1 - 0.098 12.1 0.3 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EPY54154.1 - 0.13 12.4 0.0 0.44 10.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain Ank_2 PF12796.2 EPY54155.1 - 2.3e-34 117.5 0.2 4.3e-11 42.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPY54155.1 - 3.2e-34 115.0 3.4 3.4e-07 29.7 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat zf-DHHC PF01529.15 EPY54155.1 - 3.7e-34 117.6 12.4 3.7e-34 117.6 8.6 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 EPY54155.1 - 1.7e-26 92.0 2.6 2.3e-08 34.3 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPY54155.1 - 3.8e-23 80.9 4.6 1.7e-07 31.2 0.0 4.8 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPY54155.1 - 9.6e-22 74.9 2.7 9.6e-06 25.3 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat RRM_1 PF00076.17 EPY54156.1 - 9.1e-36 121.3 0.3 1e-12 47.4 0.0 4.5 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY54156.1 - 2.9e-35 120.0 0.2 2e-11 43.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY54156.1 - 4.8e-26 90.3 0.2 3e-07 30.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPY54156.1 - 1.3e-06 28.0 0.2 0.52 10.1 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPY54156.1 - 4.5e-05 23.2 0.0 0.0067 16.2 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM PF10378.4 EPY54156.1 - 0.0019 17.7 3.3 0.0019 17.7 2.3 2.2 2 1 0 2 2 2 1 Putative RRM domain RNA_bind PF08675.6 EPY54156.1 - 0.003 17.4 0.0 2.9 7.9 0.0 3.2 3 0 0 3 3 3 1 RNA binding domain tRNA-synt_1b PF00579.20 EPY54157.1 - 1.2e-22 80.4 0.0 2.4e-22 79.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) NIF PF03031.13 EPY54157.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase ECR1_N PF14382.1 EPY54158.1 - 2.3e-16 58.7 0.2 5.8e-16 57.5 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EPY54158.1 - 0.00064 19.6 0.2 0.019 14.8 0.0 2.7 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EPY54158.1 - 0.0075 16.3 0.2 1 9.4 0.0 3.6 4 0 0 4 4 4 1 S1 RNA binding domain MRP-S28 PF10213.4 EPY54159.1 - 4.3e-36 123.7 1.7 7.1e-36 123.0 1.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein THP2 PF09432.5 EPY54159.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Tho complex subunit THP2 CryBP1 PF07029.6 EPY54159.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 CryBP1 protein PX PF00787.19 EPY54160.1 - 1.2e-27 95.9 0.3 3.7e-27 94.3 0.2 2.0 1 0 0 1 1 1 1 PX domain PLDc PF00614.17 EPY54160.1 - 9.5e-20 69.7 1.2 5.4e-10 38.7 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EPY54160.1 - 1.6e-11 44.0 0.1 4.5e-06 26.4 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain FYRC PF05965.9 EPY54160.1 - 0.0041 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus RF-1 PF00472.15 EPY54161.1 - 3.8e-37 126.5 4.5 8e-37 125.5 3.1 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EPY54161.1 - 2.3e-30 104.6 1.1 3.6e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 PCRF domain DUF1912 PF08930.5 EPY54161.1 - 0.022 14.8 1.5 0.028 14.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) RhoGAP PF00620.22 EPY54162.1 - 3.9e-16 59.0 1.4 1.1e-15 57.5 0.2 2.4 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EPY54162.1 - 7.1e-13 48.1 0.0 1.1e-11 44.3 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.18 EPY54162.1 - 6.1e-12 45.5 1.2 6.1e-12 45.5 0.8 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Flagellin_N PF00669.15 EPY54162.1 - 0.085 12.6 2.3 0.11 12.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region p450 PF00067.17 EPY54163.1 - 1.9e-73 247.6 0.0 2.3e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mnd1 PF03962.10 EPY54164.1 - 1.4e-51 174.8 4.0 1.6e-51 174.6 2.8 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 EPY54164.1 - 0.00017 21.1 4.1 0.00017 21.1 2.9 1.7 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 EPY54164.1 - 0.0003 20.8 0.4 0.00059 19.9 0.3 1.5 1 0 0 1 1 1 1 Penicillinase repressor FUR PF01475.14 EPY54164.1 - 0.00082 19.2 0.2 0.0016 18.3 0.1 1.6 1 1 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.14 EPY54164.1 - 0.0055 16.3 0.8 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Aldo_ket_red PF00248.16 EPY54164.1 - 0.025 13.4 0.1 0.032 13.0 0.1 1.4 1 1 0 1 1 1 0 Aldo/keto reductase family TFIIE_alpha PF02002.12 EPY54164.1 - 0.044 13.2 0.1 0.096 12.2 0.1 1.7 1 1 0 1 1 1 0 TFIIE alpha subunit AKNA PF12443.3 EPY54164.1 - 0.056 13.4 1.8 0.11 12.5 0.8 1.9 1 1 0 1 1 1 0 AT-hook-containing transcription factor MscS_porin PF12795.2 EPY54164.1 - 0.058 12.7 10.0 0.014 14.7 4.7 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain HXXSHH PF07586.6 EPY54164.1 - 0.078 11.8 0.6 0.11 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF4407 PF14362.1 EPY54164.1 - 0.13 11.2 2.1 0.15 10.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3322 PF11795.3 EPY54164.1 - 0.17 11.4 1.4 1.4 8.5 1.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF2802 PF10975.3 EPY54164.1 - 0.59 9.9 5.2 4.4 7.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) DIRP PF06584.8 EPY54164.1 - 0.66 9.8 3.4 4.8 7.0 0.2 2.9 3 0 0 3 3 3 0 DIRP FlxA PF14282.1 EPY54164.1 - 0.69 9.8 13.4 0.36 10.7 5.3 2.5 2 1 1 3 3 2 0 FlxA-like protein Atg14 PF10186.4 EPY54164.1 - 0.72 8.7 6.0 1 8.2 4.1 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RRF PF01765.14 EPY54164.1 - 1.1 8.7 6.1 0.33 10.3 1.8 1.8 1 1 1 2 2 2 0 Ribosome recycling factor IncA PF04156.9 EPY54164.1 - 1.2 8.6 15.5 0.072 12.6 6.2 1.9 1 1 1 2 2 2 0 IncA protein Spc24 PF08286.6 EPY54164.1 - 1.3 8.6 7.9 0.48 10.1 1.8 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 EPY54164.1 - 4 7.4 5.2 11 5.9 0.2 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) G-gamma PF00631.17 EPY54164.1 - 4.5 7.1 5.7 2.3 8.0 1.4 2.3 2 0 0 2 2 2 0 GGL domain UCH PF00443.24 EPY54165.1 - 1.3e-57 194.9 4.4 1.3e-57 194.9 3.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY54165.1 - 4.2e-23 82.2 2.9 4.2e-23 82.2 2.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPY54165.1 - 2.9e-12 46.5 13.6 2.9e-12 46.5 9.4 3.0 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M17 PF00883.16 EPY54166.1 - 7e-119 396.3 0.1 8.7e-119 396.0 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EPY54166.1 - 2.4e-06 27.3 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain TPP_enzyme_N PF02776.13 EPY54167.1 - 3.5e-34 117.7 0.0 5.4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPY54167.1 - 2.6e-28 98.4 0.0 5.9e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPY54167.1 - 1.6e-16 60.2 0.0 5.7e-16 58.4 0.0 2.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPY54167.1 - 0.003 16.5 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase CO_dh PF02552.11 EPY54167.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit CRAL_TRIO PF00650.15 EPY54168.1 - 7.9e-46 155.4 0.0 1.5e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPY54168.1 - 7.8e-14 51.5 0.1 3.4e-13 49.4 0.1 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPY54168.1 - 1.3e-13 51.0 0.0 3.9e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain GED PF02212.13 EPY54168.1 - 0.022 14.6 0.2 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain Img2 PF05046.9 EPY54169.1 - 6.9e-22 77.4 0.0 8.4e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EPY54169.1 - 0.0028 17.4 0.2 0.0049 16.6 0.1 1.4 1 1 0 1 1 1 1 Translation initiation factor SUI1 DUF3665 PF12427.3 EPY54169.1 - 0.044 13.1 0.3 0.084 12.2 0.2 1.5 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase DUF4210 PF13915.1 EPY54170.1 - 9e-17 61.1 1.5 4.6e-16 58.8 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EPY54170.1 - 1.5e-07 31.1 0.2 5.7e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation during meiosis MMS1_N PF10433.4 EPY54171.1 - 1.8e-49 168.2 4.1 1.8e-49 168.2 2.8 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EPY54171.1 - 2e-17 63.3 0.1 7.4e-17 61.4 0.0 1.8 1 1 1 2 2 2 1 CPSF A subunit region PAP2 PF01569.16 EPY54172.1 - 8.8e-12 44.8 5.6 8.8e-12 44.8 3.9 3.1 1 1 2 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EPY54172.1 - 1.4e-10 41.0 7.4 3.1e-10 39.8 5.2 1.6 1 1 0 1 1 1 1 PAP2 superfamily Prefoldin PF02996.12 EPY54173.1 - 7e-33 112.8 2.4 7e-33 112.8 1.7 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EPY54173.1 - 7.3e-05 22.4 6.3 0.0001 21.9 1.5 2.4 1 1 1 2 2 2 1 Prefoldin subunit THOC7 PF05615.8 EPY54173.1 - 0.0042 17.3 5.9 0.0065 16.7 0.4 2.1 2 0 0 2 2 2 1 Tho complex subunit 7 DUF1664 PF07889.7 EPY54173.1 - 0.014 15.2 0.7 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HR1 PF02185.11 EPY54173.1 - 0.017 14.8 0.2 0.27 11.0 0.0 2.3 2 0 0 2 2 2 0 Hr1 repeat CDC37_C PF08564.5 EPY54173.1 - 0.15 11.9 2.3 5 7.0 0.1 3.0 2 1 1 3 3 3 0 Cdc37 C terminal domain Zn_clus PF00172.13 EPY54174.1 - 9.8e-08 31.7 12.8 2.2e-07 30.6 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EPY54175.1 - 1.2e-06 28.0 0.0 2.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY54175.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY54175.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CRAL_TRIO PF00650.15 EPY54176.1 - 1.9e-37 128.2 0.0 3.6e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPY54176.1 - 3.1e-11 43.2 2.3 3.8e-11 42.9 0.6 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPY54176.1 - 2.7e-05 24.0 0.0 0.00017 21.5 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exo1 PF01612.15 EPY54177.1 - 1.1e-49 168.3 1.8 1.8e-49 167.5 0.5 2.0 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 EPY54177.1 - 1.2e-20 73.5 0.7 1.2e-20 73.5 0.5 3.1 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 EPY54177.1 - 4.2e-15 55.1 0.0 1.3e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 HRDC domain GOLD_2 PF13897.1 EPY54177.1 - 8.2 6.6 7.3 0.31 11.2 0.4 2.1 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Pkinase PF00069.20 EPY54178.1 - 4.5e-65 219.3 0.0 7.9e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54178.1 - 1.2e-41 142.4 0.0 2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY54178.1 - 5.1e-07 28.9 0.0 5.9e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPY54178.1 - 0.15 11.8 0.0 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lgl_C PF08596.5 EPY54179.1 - 1.5e-71 240.9 0.0 4.2e-70 236.2 0.0 2.1 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal DUF367 PF04034.8 EPY54180.1 - 3.6e-55 184.9 0.0 5e-55 184.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EPY54180.1 - 2.2e-12 46.3 0.1 4.4e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.14 EPY54181.1 - 4.7e-46 155.9 0.0 1.1e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.15 EPY54181.1 - 1.1e-10 41.8 0.2 2.3e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EPY54181.1 - 0.00045 20.1 3.0 0.0043 17.0 1.0 2.8 2 1 0 2 2 2 1 GAT domain IZUMO PF15005.1 EPY54181.1 - 0.019 14.9 0.4 0.041 13.9 0.3 1.6 1 0 0 1 1 1 0 Izumo sperm-egg fusion IncA PF04156.9 EPY54182.1 - 0.00015 21.4 312.6 0.0012 18.4 6.6 16.7 1 1 16 17 17 17 11 IncA protein Spc7 PF08317.6 EPY54182.1 - 0.00023 19.9 12.1 0.00023 19.9 8.4 14.4 1 1 15 16 16 16 6 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EPY54182.1 - 0.00055 17.8 46.9 0.00055 17.8 32.5 5.8 1 1 4 5 5 5 2 Myosin tail Bromodomain PF00439.20 EPY54183.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Bromodomain CwfJ_C_1 PF04677.10 EPY54184.1 - 1.2e-37 128.3 0.0 2.3e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPY54184.1 - 1.4e-25 89.6 0.4 2.7e-25 88.6 0.3 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Peptidase_M3 PF01432.15 EPY54185.1 - 4.4e-138 461.1 0.2 5.6e-138 460.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 RhoGEF PF00621.15 EPY54185.1 - 0.015 15.2 4.3 0.046 13.6 0.1 3.1 2 1 1 3 3 3 0 RhoGEF domain Hep_59 PF07052.6 EPY54186.1 - 3.3e-09 37.0 2.1 3.3e-09 37.0 1.5 2.7 2 2 1 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 GRASP55_65 PF04495.9 EPY54187.1 - 2e-53 180.1 0.0 1e-46 158.3 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EPY54187.1 - 0.00013 21.7 0.0 0.0058 16.4 0.0 2.5 1 1 1 2 2 2 1 PDZ domain DUF4526 PF15029.1 EPY54187.1 - 1.1 8.7 4.0 6.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) Mon1 PF03164.9 EPY54188.1 - 4.6e-122 407.5 9.6 5.4e-122 407.3 6.6 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Cpn60_TCP1 PF00118.19 EPY54189.1 - 1.7e-135 452.4 12.1 2e-135 452.1 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EXS PF03124.9 EPY54190.1 - 1.4e-49 168.9 21.6 1.8e-49 168.6 15.0 1.1 1 0 0 1 1 1 1 EXS family DUF3938 PF13074.1 EPY54190.1 - 0.89 9.4 6.1 11 5.8 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) Pkinase PF00069.20 EPY54191.1 - 1e-34 119.8 0.0 1.2e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54191.1 - 1.7e-23 83.0 0.0 2.2e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY54191.1 - 7.5e-06 25.8 0.0 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPY54191.1 - 0.0075 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EPY54191.1 - 0.075 12.3 0.3 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CDP-OH_P_transf PF01066.16 EPY54192.1 - 2.1e-18 66.4 5.7 2.1e-18 66.4 3.9 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Rtf2 PF04641.7 EPY54193.1 - 4.6e-63 212.8 0.3 5.5e-63 212.5 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EPY54193.1 - 1.2e-06 27.9 0.2 0.015 14.8 0.1 2.6 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPY54193.1 - 1.1e-05 25.0 1.8 1.2e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EPY54193.1 - 0.16 11.8 1.3 0.35 10.7 0.2 2.0 2 1 0 2 2 2 0 Ring finger domain Lactamase_B_2 PF12706.2 EPY54194.1 - 9.6e-32 110.1 0.0 2.7e-31 108.6 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EPY54194.1 - 1.6e-29 101.1 0.1 5.8e-29 99.3 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EPY54194.1 - 8.6e-07 28.7 0.0 2.5e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 EPY54195.1 - 1.6e-54 184.7 0.0 2.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54195.1 - 6e-18 64.8 0.0 8.5e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPY54195.1 - 0.007 15.1 0.6 0.011 14.5 0.4 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF1227 PF06777.6 EPY54196.1 - 6.5e-61 204.3 1.0 1.4e-60 203.2 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EPY54196.1 - 1.2e-52 177.7 0.1 2.6e-52 176.7 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EPY54196.1 - 3.6e-43 147.4 0.0 9.4e-43 146.0 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_11 PF13086.1 EPY54196.1 - 0.00091 18.8 0.0 0.0021 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EPY54196.1 - 0.017 14.6 0.0 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 EPY54196.1 - 0.03 14.1 0.0 0.86 9.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPY54196.1 - 0.037 12.8 0.1 0.33 9.6 0.1 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 EPY54196.1 - 0.043 13.5 1.2 0.69 9.5 0.2 2.4 1 1 1 2 2 2 0 Archaeal ATPase BolA PF01722.13 EPY54197.1 - 1.1e-26 92.5 0.3 1.5e-26 92.1 0.2 1.2 1 0 0 1 1 1 1 BolA-like protein PdxJ PF03740.8 EPY54197.1 - 0.032 13.3 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Sterol_MT_C PF08498.5 EPY54198.1 - 1.2e-25 89.2 0.2 1.9e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EPY54198.1 - 1.2e-19 70.6 0.0 2.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPY54198.1 - 2.7e-14 53.2 0.0 4.5e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPY54198.1 - 5.1e-14 52.1 0.0 9.2e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPY54198.1 - 2.4e-10 40.6 0.0 4.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPY54198.1 - 1e-09 38.7 0.2 8.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPY54198.1 - 4.5e-09 35.7 0.0 8.3e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EPY54198.1 - 9e-08 32.6 0.0 2.9e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EPY54198.1 - 1.2e-07 31.0 0.0 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EPY54198.1 - 4.7e-07 29.8 0.0 1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EPY54198.1 - 6e-05 22.4 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.11 EPY54198.1 - 0.0031 15.9 0.0 0.0062 14.9 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 EPY54198.1 - 0.03 13.9 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.14 EPY54198.1 - 0.047 13.2 0.1 1.2 8.5 0.1 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CDC48_2 PF02933.12 EPY54198.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 MTS PF05175.9 EPY54198.1 - 0.084 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain AMP-binding PF00501.23 EPY54199.1 - 1.2e-28 99.7 0.0 3.9e-17 61.7 0.0 4.1 4 0 0 4 4 4 4 AMP-binding enzyme Arf PF00025.16 EPY54200.1 - 2.2e-63 212.6 1.0 2.5e-63 212.4 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPY54200.1 - 4.5e-14 52.1 0.0 5.2e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EPY54200.1 - 2.3e-12 46.5 0.1 2.9e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPY54200.1 - 1.5e-10 40.6 0.1 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EPY54200.1 - 4.4e-10 38.8 4.9 4.1e-06 25.7 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EPY54200.1 - 4.4e-09 36.8 0.0 6.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPY54200.1 - 6.6e-09 35.7 0.0 8.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPY54200.1 - 6.4e-06 25.7 0.0 0.001 18.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EPY54200.1 - 0.0011 18.4 0.1 0.091 12.2 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EPY54200.1 - 0.003 17.7 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPY54200.1 - 0.0049 16.5 0.8 0.034 13.8 0.5 2.0 1 1 0 1 1 1 1 NACHT domain FeoB_N PF02421.13 EPY54200.1 - 0.0054 16.0 1.3 0.043 13.1 0.9 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EPY54200.1 - 0.011 15.4 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 0 Archaeal ATPase CdhD PF03599.11 EPY54200.1 - 0.025 13.0 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit AAA_22 PF13401.1 EPY54200.1 - 0.032 14.3 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPY54200.1 - 0.045 13.6 0.2 0.34 10.8 0.0 1.9 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPY54200.1 - 0.063 14.0 0.0 0.15 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EPY54200.1 - 0.081 12.3 0.3 6.4 6.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EPY54200.1 - 0.095 12.3 0.1 0.2 11.2 0.0 1.6 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EPY54200.1 - 0.095 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Lon_C PF05362.8 EPY54201.1 - 1.4e-59 200.9 0.0 2.4e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EPY54201.1 - 3.3e-37 128.1 0.6 3.3e-37 128.1 0.4 2.0 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EPY54201.1 - 2.3e-23 82.8 0.1 1.1e-22 80.6 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPY54201.1 - 6.4e-09 35.6 0.0 1.8e-08 34.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EPY54201.1 - 3.6e-06 26.4 0.0 9e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EPY54201.1 - 1e-05 25.6 1.3 0.0002 21.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPY54201.1 - 4.8e-05 23.4 1.7 0.0005 20.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EPY54201.1 - 0.00018 22.3 0.0 0.00066 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPY54201.1 - 0.0003 19.9 0.1 0.005 15.9 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPY54201.1 - 0.00043 20.1 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 EPY54201.1 - 0.00048 18.9 0.0 0.001 17.8 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain RNA_helicase PF00910.17 EPY54201.1 - 0.0022 18.1 0.0 0.0083 16.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EPY54201.1 - 0.004 17.4 0.0 0.004 17.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EPY54201.1 - 0.014 15.0 0.7 0.6 9.8 0.0 3.1 2 1 1 3 3 3 0 NTPase AAA_3 PF07726.6 EPY54201.1 - 0.024 14.2 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EPY54201.1 - 0.028 13.8 0.0 0.064 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EPY54201.1 - 0.058 12.7 0.3 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPY54201.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EPY54201.1 - 0.071 12.7 0.2 0.48 10.0 0.1 2.3 1 1 0 1 1 1 0 NACHT domain YqeY PF09424.5 EPY54202.1 - 4.7e-20 71.9 6.2 6e-20 71.5 4.3 1.1 1 0 0 1 1 1 1 Yqey-like protein KorB PF08535.5 EPY54202.1 - 0.062 13.4 0.2 0.088 12.9 0.2 1.3 1 1 0 1 1 1 0 KorB domain Pox_A3L PF05288.6 EPY54202.1 - 0.07 12.8 6.2 0.066 12.9 0.8 2.7 1 1 1 2 2 2 0 Poxvirus A3L Protein GIIM PF08388.6 EPY54202.1 - 0.09 12.5 0.6 0.36 10.6 0.0 2.0 1 1 0 2 2 2 0 Group II intron, maturase-specific domain DUF563 PF04577.9 EPY54202.1 - 0.11 12.4 0.2 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF563) DNA_pol_B_3 PF08408.5 EPY54202.1 - 0.14 12.0 1.5 0.18 11.7 1.1 1.2 1 0 0 1 1 1 0 DNA polymerase family B viral insert SPT16 PF08644.6 EPY54202.1 - 0.23 11.3 2.9 0.27 11.0 2.0 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) ING PF12998.2 EPY54202.1 - 0.44 10.8 6.0 3.5 7.9 0.5 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Vsr PF03852.10 EPY54202.1 - 0.5 10.0 2.3 1.3 8.6 0.1 2.3 3 0 0 3 3 3 0 DNA mismatch endonuclease Vsr Fib_alpha PF08702.5 EPY54202.1 - 1.6 8.8 6.1 3.9 7.5 0.5 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ATP-synt_G PF04718.10 EPY54203.1 - 3.3e-10 40.5 0.9 2.2e-06 28.2 0.1 2.3 1 1 1 2 2 2 2 Mitochondrial ATP synthase g subunit DEAD PF00270.24 EPY54204.1 - 4.8e-39 133.5 0.0 1.9e-38 131.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY54204.1 - 4.2e-29 100.2 0.1 2.6e-28 97.6 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPY54204.1 - 7e-10 38.1 0.0 5.7e-09 35.1 0.0 1.9 1 1 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EPY54204.1 - 2.1e-09 37.5 0.0 4.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EPY54204.1 - 0.0041 16.1 0.0 0.0089 15.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EPY54204.1 - 0.014 15.5 0.2 0.1 12.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EPY54204.1 - 0.019 14.6 0.0 0.061 13.0 0.0 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain Ank_2 PF12796.2 EPY54205.1 - 3.4e-20 72.1 1.1 8.3e-13 48.5 0.2 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPY54205.1 - 8.9e-18 63.1 1.0 4.9e-08 32.3 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EPY54205.1 - 7.8e-16 56.6 0.9 1.6e-06 27.7 0.1 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EPY54205.1 - 2.5e-15 56.1 1.7 3.1e-07 30.4 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPY54205.1 - 1.1e-13 51.3 3.0 3.2e-06 27.5 0.1 4.8 2 1 3 5 5 5 3 Ankyrin repeats (many copies) KilA-N PF04383.8 EPY54205.1 - 0.00015 21.3 0.1 0.0012 18.4 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Fib_alpha PF08702.5 EPY54205.1 - 0.00052 20.1 1.4 0.0014 18.7 1.0 1.7 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family GCS PF03074.11 EPY54206.1 - 4.5e-166 552.4 0.1 6.1e-166 552.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase zf-C2H2_jaz PF12171.3 EPY54207.1 - 3.9e-06 26.8 0.1 3.9e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPY54207.1 - 6.2e-05 23.0 0.8 0.00012 22.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EPY54207.1 - 0.0011 18.5 0.1 0.0022 17.6 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF1777 PF08648.7 EPY54207.1 - 0.24 11.0 10.8 0.02 14.6 4.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) RGS PF00615.14 EPY54208.1 - 2e-18 66.5 0.2 1.4e-17 63.8 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 EPY54208.1 - 1.6e-05 24.5 0.1 0.00078 19.1 0.0 3.0 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MgrB PF13998.1 EPY54208.1 - 0.18 11.6 1.6 0.41 10.4 1.1 1.6 1 0 0 1 1 1 0 MgrB protein Hamartin PF04388.7 EPY54209.1 - 7.4e-80 269.4 24.3 9.9e-78 262.4 16.9 2.2 1 1 0 1 1 1 1 Hamartin protein Tho2 PF11262.3 EPY54210.1 - 1.3e-81 273.9 3.6 3.5e-81 272.5 2.5 1.8 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EPY54210.1 - 2.7e-29 100.7 0.0 8.7e-29 99.1 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PAM2 PF07145.10 EPY54210.1 - 0.035 13.6 0.2 0.078 12.5 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Pkinase PF00069.20 EPY54211.1 - 7.1e-58 195.7 0.0 1.2e-57 195.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54211.1 - 9e-36 123.2 0.0 2.4e-35 121.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPY54211.1 - 0.003 16.5 0.0 0.0063 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like EMP24_GP25L PF01105.19 EPY54214.1 - 3e-37 128.0 0.9 3.5e-37 127.8 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AAA PF00004.24 EPY54215.1 - 1.8e-92 306.4 0.0 2.6e-46 157.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPY54215.1 - 1.2e-15 57.1 0.0 3.5e-08 32.7 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EPY54215.1 - 8.5e-13 49.1 0.0 2.5e-07 31.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPY54215.1 - 9.6e-13 48.5 5.1 8.6e-05 22.6 0.1 5.3 4 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 EPY54215.1 - 3.5e-12 46.5 0.2 0.003 17.6 0.0 5.1 3 3 1 4 4 4 2 AAA domain AAA_5 PF07728.9 EPY54215.1 - 4.7e-12 45.8 0.4 0.0002 21.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPY54215.1 - 6.3e-12 45.5 0.1 1.9e-05 24.5 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EPY54215.1 - 6e-11 42.7 0.0 1.2e-06 28.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EPY54215.1 - 6.3e-11 42.4 0.0 0.00091 19.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPY54215.1 - 1.3e-10 41.2 0.0 0.00054 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EPY54215.1 - 1.8e-10 40.9 0.0 0.0011 19.1 0.0 3.9 4 1 0 4 4 3 2 RNA helicase Zeta_toxin PF06414.7 EPY54215.1 - 3.9e-09 35.8 0.0 0.0014 17.7 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EPY54215.1 - 5.8e-09 35.1 0.0 0.00018 20.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EPY54215.1 - 3.5e-08 33.0 2.4 0.0072 16.0 0.1 3.8 4 1 0 4 4 2 2 Part of AAA domain AAA_28 PF13521.1 EPY54215.1 - 4.2e-08 33.3 0.1 0.0019 18.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EPY54215.1 - 4.4e-08 32.7 0.0 0.0081 15.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 EPY54215.1 - 7.8e-08 31.9 6.3 0.1 11.9 0.0 5.0 2 2 3 5 5 5 2 AAA domain NACHT PF05729.7 EPY54215.1 - 1.2e-07 31.5 0.2 0.0083 15.7 0.0 3.5 3 1 1 4 4 3 2 NACHT domain Mg_chelatase PF01078.16 EPY54215.1 - 1.2e-07 31.0 0.6 0.0066 15.6 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPY54215.1 - 2.8e-07 30.2 0.0 0.0048 16.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 EPY54215.1 - 1.4e-06 28.3 0.0 0.00096 19.1 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family Vps4_C PF09336.5 EPY54215.1 - 3.7e-06 26.7 0.5 0.00032 20.5 0.0 3.1 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.8 EPY54215.1 - 4.5e-06 25.7 0.0 0.017 14.0 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EPY54215.1 - 4.8e-06 26.9 0.0 0.17 12.1 0.0 3.1 2 1 0 2 2 2 2 ABC transporter KaiC PF06745.8 EPY54215.1 - 9.2e-06 24.9 0.0 0.22 10.6 0.0 3.3 3 0 0 3 3 3 2 KaiC SKI PF01202.17 EPY54215.1 - 1.5e-05 24.8 0.2 0.13 12.1 0.0 3.4 3 0 0 3 3 2 2 Shikimate kinase Sigma54_activ_2 PF14532.1 EPY54215.1 - 4.4e-05 23.5 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EPY54215.1 - 6.6e-05 22.4 0.0 0.24 10.8 0.0 3.4 3 1 0 3 3 3 1 Sigma-54 interaction domain ATP-synt_ab PF00006.20 EPY54215.1 - 0.00012 21.6 0.0 0.45 9.9 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 EPY54215.1 - 0.00019 20.7 0.1 0.57 9.3 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.13 EPY54215.1 - 0.00021 20.8 0.3 0.95 8.9 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EPY54215.1 - 0.0003 19.7 0.0 0.33 9.7 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain AAA_11 PF13086.1 EPY54215.1 - 0.00034 20.2 0.6 0.73 9.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AFG1_ATPase PF03969.11 EPY54215.1 - 0.00041 19.2 0.0 0.47 9.2 0.0 3.3 3 0 0 3 3 3 1 AFG1-like ATPase Arch_ATPase PF01637.13 EPY54215.1 - 0.00051 19.8 0.0 1.4 8.5 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase Rad17 PF03215.10 EPY54215.1 - 0.00059 18.6 0.0 0.19 10.3 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 EPY54215.1 - 0.00084 18.2 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 EPY54215.1 - 0.0014 18.4 0.7 3.3 7.5 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EPY54215.1 - 0.0017 17.9 0.0 0.85 9.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EPY54215.1 - 0.0028 17.2 0.0 1.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EPY54215.1 - 0.0074 15.9 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EPY54215.1 - 0.0086 15.7 0.1 2.5 7.7 0.0 3.2 4 0 0 4 4 2 1 NTPase SRPRB PF09439.5 EPY54215.1 - 0.012 14.8 0.0 4.6 6.4 0.0 2.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.4 EPY54215.1 - 0.034 13.1 0.6 2.2 7.1 0.0 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.18 EPY54215.1 - 0.035 14.0 0.0 8.4 6.3 0.0 3.9 2 2 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPY54215.1 - 0.039 13.4 0.0 9.3 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IPT PF01745.11 EPY54215.1 - 0.043 12.9 0.2 6.1 5.9 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase Guanylate_kin PF00625.16 EPY54215.1 - 0.044 13.2 0.0 14 5.0 0.0 3.8 2 2 2 4 4 4 0 Guanylate kinase Bac_DnaA PF00308.13 EPY54215.1 - 0.053 13.1 0.0 2.5 7.6 0.0 2.8 3 1 0 3 3 2 0 Bacterial dnaA protein AAA_10 PF12846.2 EPY54215.1 - 0.84 9.0 7.8 19 4.5 0.0 3.8 3 2 0 3 3 3 0 AAA-like domain HECT PF00632.20 EPY54216.1 - 6.5e-93 311.3 0.0 9.7e-93 310.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPY54216.1 - 1.6e-33 114.1 22.8 3.4e-11 42.7 1.7 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EPY54216.1 - 5.5e-14 51.7 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 EPY54217.1 - 5.4e-17 61.1 0.0 1.4e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY54217.1 - 1.8e-14 53.4 0.0 4.5e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY54217.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.10 EPY54217.1 - 0.0027 17.1 4.7 0.0041 16.5 3.3 1.3 1 0 0 1 1 1 1 Septum formation initiator WEMBL PF05701.6 EPY54217.1 - 0.0097 14.4 2.7 0.011 14.2 1.9 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Flagellin_C PF00700.16 EPY54217.1 - 0.018 15.1 0.3 0.026 14.6 0.2 1.3 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region APG6 PF04111.7 EPY54217.1 - 0.023 13.7 0.7 0.025 13.6 0.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Striatin PF08232.7 EPY54217.1 - 0.043 14.1 1.1 0.054 13.7 0.8 1.2 1 0 0 1 1 1 0 Striatin family GAS PF13851.1 EPY54217.1 - 0.049 12.8 1.7 0.063 12.4 1.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Talin_middle PF09141.5 EPY54217.1 - 0.052 13.2 0.3 0.062 12.9 0.2 1.1 1 0 0 1 1 1 0 Talin, middle domain PEARLI-4 PF05278.7 EPY54217.1 - 0.064 12.6 1.4 0.074 12.4 1.0 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) BLOC1_2 PF10046.4 EPY54217.1 - 0.067 13.3 0.7 0.098 12.8 0.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.1 EPY54217.1 - 0.11 12.9 1.5 0.16 12.4 1.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.6 EPY54217.1 - 0.13 10.9 2.3 0.18 10.4 1.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF972 PF06156.8 EPY54217.1 - 0.18 12.1 1.1 0.25 11.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) T2SM PF04612.7 EPY54217.1 - 0.31 10.8 2.5 0.43 10.3 1.7 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M IncA PF04156.9 EPY54217.1 - 0.4 10.2 2.1 0.46 10.0 1.4 1.1 1 0 0 1 1 1 0 IncA protein DUF724 PF05266.9 EPY54217.1 - 0.47 10.0 3.2 0.58 9.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2630 PF10944.3 EPY54217.1 - 0.52 10.4 5.0 0.78 9.8 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) DUF4337 PF14235.1 EPY54217.1 - 2 8.2 4.1 2.7 7.7 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Coa1 PF08695.5 EPY54219.1 - 4.4e-29 100.3 0.0 7.7e-29 99.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF645 PF04875.7 EPY54219.1 - 0.014 15.0 0.4 0.12 12.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF645 CUE PF02845.11 EPY54220.1 - 3.6e-11 42.3 0.0 9e-11 41.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain Hap4_Hap_bind PF10297.4 EPY54221.1 - 2.9e-07 30.0 9.7 2.9e-07 30.0 6.8 2.4 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF2762 PF10960.3 EPY54221.1 - 0.085 12.5 1.2 0.19 11.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DnaG_DnaB_bind PF08278.6 EPY54221.1 - 0.15 12.3 2.3 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding IncA PF04156.9 EPY54221.1 - 0.25 10.9 4.4 0.42 10.1 3.1 1.3 1 0 0 1 1 1 0 IncA protein UPF0449 PF15136.1 EPY54221.1 - 8.8 6.6 8.0 0.91 9.7 0.8 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 FMO-like PF00743.14 EPY54222.1 - 2.2e-33 115.2 0.0 3.6e-22 78.2 0.0 3.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPY54222.1 - 9.9e-17 61.6 0.0 2.9e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPY54222.1 - 8.5e-13 48.3 0.0 1.3e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPY54222.1 - 2.5e-07 29.9 0.4 2.7e-05 23.2 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPY54222.1 - 2.6e-06 27.3 0.0 5.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPY54222.1 - 0.00015 21.6 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPY54222.1 - 0.00036 19.5 0.0 0.014 14.2 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPY54222.1 - 0.00072 18.7 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EPY54222.1 - 0.018 13.5 0.3 0.028 12.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Adap_comp_sub PF00928.16 EPY54223.1 - 3.2e-90 301.7 0.0 4e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPY54223.1 - 8.7e-07 28.7 0.8 1.4e-06 28.0 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 EPY54223.1 - 0.012 14.2 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 RRM_1 PF00076.17 EPY54224.1 - 4.3e-11 42.2 0.2 1.9e-10 40.1 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY54224.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY54224.1 - 4.4e-06 26.5 0.0 1.1e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Toxin_57 PF15535.1 EPY54224.1 - 0.41 10.7 2.3 2.3 8.3 0.2 2.5 2 0 0 2 2 2 0 Putative toxin 57 Ank_5 PF13857.1 EPY54225.1 - 2.8e-18 65.5 2.1 7.3e-10 38.7 0.2 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPY54225.1 - 6.7e-18 64.8 0.9 1e-09 38.5 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPY54225.1 - 4.5e-16 58.8 0.2 1.9e-07 31.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EPY54225.1 - 4.6e-15 54.5 3.0 9.7e-10 37.7 0.3 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EPY54225.1 - 9.4e-13 47.0 1.6 3.1e-06 26.9 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat UQ_con PF00179.21 EPY54226.1 - 1.7e-48 163.6 0.0 1.9e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAT PF02259.18 EPY54227.1 - 3.3e-67 226.9 7.2 3.3e-67 226.9 5.0 2.4 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EPY54227.1 - 8.1e-22 77.8 0.1 2.3e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPY54227.1 - 5.3e-06 25.7 0.5 1.3e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 FATC domain Gp58 PF07902.6 EPY54227.1 - 0.23 9.6 0.2 0.45 8.6 0.1 1.3 1 0 0 1 1 1 0 gp58-like protein Cyclin_N PF00134.18 EPY54228.1 - 1.7e-09 37.2 0.1 3.3e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 EPY54229.1 - 6.5e-07 29.0 3.6 0.0012 18.6 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Ecotin PF03974.8 EPY54229.1 - 0.071 12.8 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 Ecotin DUF1317 PF07026.6 EPY54229.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) Sulfate_transp PF00916.15 EPY54230.1 - 2.6e-77 259.5 7.6 4.3e-77 258.8 5.3 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EPY54230.1 - 1.7e-32 110.9 2.9 1.7e-32 110.9 2.0 3.0 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EPY54230.1 - 7.2e-14 51.2 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Transket_pyr PF02779.19 EPY54231.1 - 1.4e-64 216.8 0.0 2.6e-64 216.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EPY54231.1 - 5.3e-57 192.8 0.0 7.6e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Thioredoxin PF00085.15 EPY54232.1 - 2.4e-24 85.0 0.0 3e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPY54232.1 - 5e-07 29.7 0.1 4.6e-06 26.6 0.0 1.9 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EPY54232.1 - 3.9e-06 27.0 0.1 7.2e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EPY54232.1 - 0.00042 19.8 0.0 0.00054 19.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EPY54232.1 - 0.0012 18.4 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPY54232.1 - 0.0024 17.5 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EPY54232.1 - 0.0037 17.2 0.1 0.028 14.4 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like DIM1 PF02966.11 EPY54232.1 - 0.08 12.4 0.0 0.098 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Cyclin_N PF00134.18 EPY54233.1 - 5.1e-13 48.7 1.1 8e-12 44.8 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EPY54233.1 - 0.0012 18.5 0.4 0.0051 16.5 0.1 2.1 2 1 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EPY54233.1 - 0.0049 16.7 0.3 0.5 10.3 0.0 2.6 2 1 0 2 2 2 1 Cyclin, C-terminal domain Mito_carr PF00153.22 EPY54234.1 - 1.4e-69 229.8 2.4 1.1e-23 82.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 EPY54235.1 - 2.8e-49 166.8 0.0 3.5e-47 160.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY54235.1 - 1.4e-26 92.1 0.1 3.2e-26 90.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 EPY54235.1 - 0.0024 18.1 1.0 0.0075 16.5 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) ResIII PF04851.10 EPY54235.1 - 0.032 14.0 0.0 0.14 11.9 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Peripla_BP_1 PF00532.16 EPY54235.1 - 0.072 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family HORMA PF02301.13 EPY54236.1 - 1.3e-18 67.2 0.1 1.8e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 HORMA domain ArfGap PF01412.13 EPY54236.1 - 0.086 12.6 0.4 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Pkinase PF00069.20 EPY54237.1 - 1.6e-65 220.8 0.0 6.4e-65 218.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54237.1 - 5.6e-38 130.5 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EPY54237.1 - 7.9e-28 96.0 17.8 2.2e-16 59.3 3.8 3.2 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 EPY54237.1 - 2.4e-20 72.0 30.0 2e-10 40.2 7.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EPY54237.1 - 1e-13 51.5 1.5 3.4e-13 49.8 1.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPY54237.1 - 6.6e-05 22.0 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Prok-RING_1 PF14446.1 EPY54237.1 - 0.00072 19.2 5.3 0.00072 19.2 3.7 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Uds1 PF15456.1 EPY54237.1 - 0.014 15.3 2.3 0.014 15.3 1.6 4.0 4 2 0 4 4 4 0 Up-regulated During Septation Cpn60_TCP1 PF00118.19 EPY54238.1 - 4.3e-143 477.4 11.8 4.9e-143 477.2 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PACT_coil_coil PF10495.4 EPY54238.1 - 0.1 12.5 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Sad1_UNC PF07738.8 EPY54239.1 - 1.3e-37 128.5 0.0 2.7e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DNA_pol_delta_4 PF04081.8 EPY54240.1 - 1.2e-38 132.1 0.3 1.7e-38 131.6 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 RNA_pol_Rpb1_6 PF04992.9 EPY54240.1 - 0.012 15.4 0.4 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 Abhydrolase_6 PF12697.2 EPY54241.1 - 1.8e-10 41.0 0.0 2.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPY54241.1 - 3.6e-10 39.7 0.0 5.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPY54241.1 - 1.3e-06 28.0 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EPY54241.1 - 3.3e-06 26.9 0.0 9.9e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EPY54241.1 - 1.2e-05 24.7 0.2 4.2e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EPY54241.1 - 5.7e-05 22.4 0.1 0.00018 20.8 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 EPY54241.1 - 0.00011 20.5 0.0 0.23 9.6 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.7 EPY54241.1 - 0.00036 19.1 0.0 0.0012 17.4 0.0 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF1100 PF06500.6 EPY54241.1 - 0.011 14.2 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PFK PF00365.15 EPY54242.1 - 7.3e-166 550.1 6.4 1.6e-120 401.3 1.9 2.2 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 EPY54242.1 - 0.00031 21.3 0.0 0.001 19.6 0.0 1.9 1 0 0 1 1 1 1 Glyoxalase-like domain ThiF PF00899.16 EPY54243.1 - 4.2e-38 130.2 0.1 1.1e-37 128.9 0.1 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EPY54243.1 - 1.7e-31 107.5 0.6 3.2e-31 106.6 0.4 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPY54243.1 - 1.6e-20 72.1 2.5 1.6e-20 72.1 1.7 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EPY54243.1 - 5.6e-08 32.7 0.6 1.5e-07 31.3 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EPY54243.1 - 1.3e-05 25.2 0.0 3.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EPY54243.1 - 0.0045 17.2 0.1 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 EPY54243.1 - 0.012 14.5 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EPY54243.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pho88 PF10032.4 EPY54244.1 - 4.4e-58 195.6 0.1 4.9e-58 195.5 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4042 PF13251.1 EPY54244.1 - 0.097 12.1 0.4 0.55 9.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) DUF2955 PF11168.3 EPY54244.1 - 0.32 10.6 3.4 3.6 7.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) Pro_isomerase PF00160.16 EPY54245.1 - 2.2e-40 138.4 0.0 5.4e-40 137.1 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD V_ATPase_I PF01496.14 EPY54245.1 - 0.33 8.7 2.2 0.49 8.1 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EPY54245.1 - 2.2 7.8 10.3 0.22 11.1 3.1 2.1 2 0 0 2 2 2 0 Mnd1 family APG6 PF04111.7 EPY54245.1 - 9 5.2 12.7 0.49 9.3 5.1 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3807 PF12720.2 EPY54246.1 - 1.6e-24 87.0 0.1 2e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) GEMIN8 PF15348.1 EPY54246.1 - 6.4e-06 26.3 0.3 8.9e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 UCR_TM PF02921.9 EPY54247.1 - 6.4e-19 67.9 4.1 5.9e-18 64.8 0.7 2.4 2 0 0 2 2 2 2 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EPY54247.1 - 4.3e-17 61.4 0.1 8.7e-17 60.4 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Metallophos PF00149.23 EPY54248.1 - 8.3e-39 133.0 0.5 1.2e-38 132.5 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.22 EPY54249.1 - 2.2e-47 160.7 0.0 8.1e-23 81.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EPY54249.1 - 7.5e-19 67.3 2.9 7.5e-19 67.3 2.0 2.4 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EPY54249.1 - 3.3e-18 66.6 10.7 0.00078 19.4 0.1 4.6 2 2 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EPY54249.1 - 5e-10 38.7 0.1 0.00042 19.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EPY54249.1 - 4.6e-09 35.8 1.5 0.0031 16.7 0.3 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPY54249.1 - 1.1e-07 32.3 13.6 0.00034 21.0 0.2 3.8 3 2 1 4 4 4 2 AAA domain AAA_22 PF13401.1 EPY54249.1 - 1.4e-07 31.6 0.1 0.014 15.5 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EPY54249.1 - 2.6e-07 31.4 0.2 0.017 15.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EPY54249.1 - 4.1e-07 30.5 0.0 0.057 13.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EPY54249.1 - 6.9e-07 28.6 5.5 0.16 10.9 0.0 4.7 3 1 0 4 4 4 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EPY54249.1 - 2.2e-06 27.2 0.0 0.021 14.3 0.0 2.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EPY54249.1 - 2.9e-06 27.1 0.0 0.0072 16.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EPY54249.1 - 6.2e-06 26.5 2.7 0.15 12.3 0.1 3.5 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EPY54249.1 - 8.5e-06 25.0 0.0 0.016 14.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 EPY54249.1 - 1.9e-05 24.4 0.9 0.12 12.0 0.0 2.9 3 0 0 3 3 3 2 NACHT domain Dynamin_N PF00350.18 EPY54249.1 - 2.8e-05 23.9 3.1 0.17 11.6 0.0 3.8 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.1 EPY54249.1 - 8e-05 22.7 0.4 0.21 11.5 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EPY54249.1 - 9.9e-05 21.8 0.1 0.16 11.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EPY54249.1 - 0.00021 20.8 0.4 0.43 9.9 0.1 2.8 3 0 0 3 3 2 2 AAA-like domain RNA_helicase PF00910.17 EPY54249.1 - 0.00029 20.9 0.1 0.8 9.9 0.0 2.8 3 0 0 3 3 2 2 RNA helicase MobB PF03205.9 EPY54249.1 - 0.00056 19.6 0.1 0.16 11.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EPY54249.1 - 0.00065 19.6 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EPY54249.1 - 0.0011 18.8 3.5 0.73 9.6 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EPY54249.1 - 0.0013 18.4 0.1 1.4 8.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPY54249.1 - 0.0017 18.2 0.0 0.87 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EPY54249.1 - 0.0049 16.7 0.3 3.5 7.6 0.0 3.4 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.13 EPY54249.1 - 0.0049 15.9 0.1 1.7 7.5 0.0 2.5 2 0 0 2 2 2 1 Septin FeoB_N PF02421.13 EPY54249.1 - 0.0063 15.7 0.1 0.08 12.2 0.0 2.5 3 0 0 3 3 2 1 Ferrous iron transport protein B G-alpha PF00503.15 EPY54249.1 - 0.011 14.5 0.5 0.055 12.1 0.2 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.24 EPY54249.1 - 0.013 15.6 0.0 2.4 8.3 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EPY54249.1 - 0.016 14.0 0.1 6.2 5.5 0.0 2.7 2 1 0 2 2 2 0 NB-ARC domain DAP3 PF10236.4 EPY54249.1 - 0.017 14.1 0.9 6.2 5.6 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 EPY54249.1 - 0.019 14.5 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EPY54249.1 - 0.019 13.7 0.0 2.6 6.7 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_24 PF13479.1 EPY54249.1 - 0.019 14.5 0.6 2.6 7.5 0.1 3.0 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.7 EPY54249.1 - 0.023 13.9 0.8 6.5 5.9 0.0 2.8 2 1 1 3 3 3 0 Poxvirus A32 protein KaiC PF06745.8 EPY54249.1 - 0.026 13.6 0.1 5.9 5.9 0.0 3.0 3 0 0 3 3 3 0 KaiC ATP-synt_ab PF00006.20 EPY54249.1 - 0.039 13.4 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EPY54249.1 - 0.042 12.7 0.0 2.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.4 EPY54249.1 - 0.081 11.5 0.5 11 4.4 0.1 2.9 3 1 1 4 4 4 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 EPY54249.1 - 0.097 12.3 0.0 5.4 6.6 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 EPY54249.1 - 0.12 12.1 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_13 PF13166.1 EPY54249.1 - 0.48 8.8 7.5 1.7 6.9 0.0 3.2 3 1 1 4 4 4 0 AAA domain Glyco_transf_15 PF01793.11 EPY54250.1 - 1.5e-130 435.0 9.9 1.8e-130 434.7 6.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Bacillus_HBL PF05791.6 EPY54250.1 - 0.015 14.6 0.2 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) OB_NTP_bind PF07717.11 EPY54251.1 - 3.8e-25 87.9 0.0 9.6e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPY54251.1 - 8.1e-25 86.8 0.0 1.8e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPY54251.1 - 7.6e-12 44.9 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPY54251.1 - 8e-09 35.2 0.2 2e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPY54251.1 - 1.4e-06 28.4 0.2 1.7e-05 24.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.17 EPY54251.1 - 9.5e-05 21.9 0.2 0.00046 19.6 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EPY54251.1 - 0.00027 20.8 0.0 0.34 10.7 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EPY54251.1 - 0.0093 15.7 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EPY54251.1 - 0.011 14.7 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EPY54251.1 - 0.013 15.8 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EPY54251.1 - 0.029 13.6 0.0 0.26 10.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 EPY54251.1 - 0.039 13.8 1.1 4.1 7.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EPY54251.1 - 0.079 13.1 0.2 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EPY54251.1 - 0.18 12.0 0.1 0.81 9.9 0.0 1.9 1 1 1 2 2 2 0 ABC transporter PRMT5 PF05185.11 EPY54252.1 - 3e-156 520.8 0.0 3.6e-156 520.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DUF2433 PF10360.4 EPY54253.1 - 3.6e-39 134.1 0.5 7.3e-39 133.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EPY54253.1 - 0.0052 16.2 0.0 0.036 13.4 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 EPY54255.1 - 6.9e-15 55.3 0.1 1.9e-14 53.9 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPY54255.1 - 6.3e-06 26.1 0.1 8.1e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPY54255.1 - 3.7e-05 23.2 0.1 0.00011 21.7 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPY54255.1 - 3.8e-05 22.5 0.0 5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPY54255.1 - 0.00011 21.1 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EPY54255.1 - 0.00012 21.7 0.4 0.02 14.5 0.0 2.1 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EPY54255.1 - 0.00038 20.4 0.0 0.00081 19.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPY54255.1 - 0.089 11.6 1.5 0.46 9.3 1.1 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein IGPD PF00475.13 EPY54256.1 - 7.2e-60 201.0 0.2 9.4e-60 200.6 0.1 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase rve PF00665.21 EPY54256.1 - 0.067 13.3 0.0 14 5.7 0.0 2.6 3 0 0 3 3 3 0 Integrase core domain Clenterotox PF03505.9 EPY54257.1 - 0.085 12.2 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Clostridium enterotoxin DUF775 PF05603.7 EPY54258.1 - 5.8e-58 195.7 0.0 7.1e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) WD40 PF00400.27 EPY54259.1 - 9.1e-11 41.2 0.9 0.72 9.8 0.0 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat TFIID_30kDa PF03540.8 EPY54260.1 - 2.6e-25 87.9 0.1 4.4e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CDC45 PF02724.9 EPY54260.1 - 1.3 6.9 4.2 1.3 6.9 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.24 EPY54261.1 - 6.5e-44 149.4 0.0 1.2e-43 148.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPY54261.1 - 8.6e-24 83.2 0.0 2.1e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EPY54261.1 - 1.6e-22 78.8 0.1 3.7e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EPY54261.1 - 1.6e-05 24.8 3.8 2.2e-05 24.3 0.0 2.8 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Hist_deacetyl PF00850.14 EPY54262.1 - 4.2e-82 275.9 0.5 5.6e-82 275.5 0.3 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF1256 PF06866.6 EPY54262.1 - 0.042 13.0 0.2 0.089 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) NIL PF09383.5 EPY54262.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 NIL domain PALP PF00291.20 EPY54263.1 - 3.1e-61 207.2 0.0 3.8e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme polyprenyl_synt PF00348.12 EPY54264.1 - 3.4e-49 167.0 0.0 4.7e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase IKI3 PF04762.7 EPY54265.1 - 8.9e-293 973.6 0.0 1.2e-292 973.1 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Clathrin PF00637.15 EPY54265.1 - 0.0024 17.4 9.9 0.0061 16.1 0.4 3.7 1 1 2 3 3 3 2 Region in Clathrin and VPS COG2 PF06148.6 EPY54266.1 - 2.8e-16 59.6 6.8 4e-16 59.0 4.7 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 EPY54266.1 - 0.00035 18.8 1.9 0.00043 18.5 1.3 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF4631 PF15450.1 EPY54266.1 - 0.0027 16.0 4.6 0.0036 15.6 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) GLTP PF08718.6 EPY54266.1 - 0.016 15.2 3.9 0.034 14.1 2.7 1.6 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) Sec8_exocyst PF04048.9 EPY54266.1 - 0.018 14.6 5.0 0.027 14.1 3.0 1.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Vps51 PF08700.6 EPY54266.1 - 0.018 14.8 3.9 0.073 12.9 0.4 2.8 2 1 1 3 3 3 0 Vps51/Vps67 CCDC-167 PF15188.1 EPY54266.1 - 0.02 14.8 5.5 1.1 9.2 1.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Fib_alpha PF08702.5 EPY54266.1 - 0.021 14.9 2.7 0.025 14.7 1.0 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MCPsignal PF00015.16 EPY54266.1 - 0.047 13.2 0.3 0.067 12.7 0.2 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IncA PF04156.9 EPY54266.1 - 0.078 12.5 5.5 0.12 12.0 3.8 1.3 1 0 0 1 1 1 0 IncA protein DUF4315 PF14193.1 EPY54266.1 - 0.17 11.8 4.7 0.16 11.9 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) DUF4404 PF14357.1 EPY54266.1 - 0.23 11.8 4.5 0.22 11.9 2.1 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4404) IL6 PF00489.12 EPY54266.1 - 0.26 10.8 3.3 3.9 7.0 0.7 2.5 1 1 1 2 2 2 0 Interleukin-6/G-CSF/MGF family ZYG-11_interact PF05884.7 EPY54266.1 - 0.26 10.3 1.8 0.35 9.8 1.3 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF16 PF01519.11 EPY54266.1 - 0.28 11.4 3.8 0.47 10.7 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF3153 PF11353.3 EPY54266.1 - 0.51 9.7 5.4 1 8.7 2.4 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3153) Erp_C PF06780.6 EPY54266.1 - 0.58 9.9 6.4 0.86 9.4 3.0 1.9 1 1 1 2 2 2 0 Erp protein C-terminus Retrotrans_gag PF03732.12 EPY54266.1 - 0.61 10.1 4.3 0.38 10.8 1.3 1.9 2 1 0 2 2 1 0 Retrotransposon gag protein OmpH PF03938.9 EPY54266.1 - 3.8 7.4 9.2 6.2 6.7 5.6 1.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF972 PF06156.8 EPY54266.1 - 7.9 6.8 8.1 6.5 7.1 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3449 PF11931.3 EPY54267.1 - 1.5e-76 256.3 0.7 2.9e-73 245.5 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EPY54267.1 - 5.9e-07 28.9 1.2 5.9e-07 28.9 0.8 2.3 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EPY54267.1 - 2.6e-06 27.4 4.2 0.00018 21.5 0.7 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPY54267.1 - 4.8e-06 26.5 7.3 1.4e-05 25.0 2.2 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPY54267.1 - 0.0016 18.5 1.7 0.064 13.3 0.3 2.7 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EPY54267.1 - 0.029 14.0 0.5 0.029 14.0 0.4 2.6 2 1 0 2 2 2 0 DBF zinc finger RNase_H2_suC PF08615.6 EPY54267.1 - 0.054 13.3 0.0 0.3 10.9 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF951 PF06107.6 EPY54267.1 - 0.12 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Aldedh PF00171.17 EPY54267.1 - 0.14 10.4 0.7 0.31 9.3 0.0 1.8 2 0 0 2 2 2 0 Aldehyde dehydrogenase family PRELI PF04707.9 EPY54268.1 - 2.5e-53 179.8 0.1 2.9e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Glycophorin_A PF01102.13 EPY54269.1 - 0.00027 20.7 0.0 0.00081 19.1 0.0 1.8 1 0 0 1 1 1 1 Glycophorin A Syndecan PF01034.15 EPY54269.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Plasmodium_Vir PF05795.6 EPY54269.1 - 0.032 13.4 0.3 0.032 13.4 0.2 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Peptidase_M50 PF02163.17 EPY54269.1 - 0.067 12.1 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M50 E1-E2_ATPase PF00122.15 EPY54269.1 - 0.094 11.7 0.1 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 E1-E2 ATPase Mid2 PF04478.7 EPY54269.1 - 1.9 7.8 6.1 0.2 11.0 0.5 2.1 2 1 1 3 3 3 0 Mid2 like cell wall stress sensor SGS PF05002.10 EPY54270.1 - 3.5e-30 103.5 3.0 3.5e-30 103.5 2.1 1.9 2 0 0 2 2 2 1 SGS domain CS PF04969.11 EPY54270.1 - 1.3e-14 54.5 0.0 2.8e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EPY54270.1 - 0.009 15.6 1.0 0.019 14.5 0.7 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EPY54270.1 - 0.033 13.8 0.1 0.077 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat USP7_ICP0_bdg PF12436.3 EPY54271.1 - 4.9e-68 229.0 3.8 4.8e-64 215.9 0.0 4.0 2 2 2 4 4 4 3 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EPY54271.1 - 8.9e-59 198.4 6.1 3.2e-58 196.6 1.2 2.5 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EPY54271.1 - 1.6e-57 194.7 0.5 3.6e-57 193.5 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPY54271.1 - 2.3e-31 109.3 0.0 4.4e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EPY54271.1 - 2.2e-07 31.1 0.0 8e-05 22.8 0.0 4.2 3 1 0 3 3 3 1 MATH domain FAD-oxidase_C PF02913.14 EPY54273.1 - 1.1e-64 218.1 0.0 1.5e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPY54273.1 - 8.1e-33 112.8 0.0 1.3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain WD40 PF00400.27 EPY54274.1 - 5e-52 172.0 31.1 5.5e-13 48.2 0.0 12.0 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.7 EPY54274.1 - 4.3e-23 81.3 0.1 7.1e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nbas_N PF15492.1 EPY54274.1 - 0.00027 20.1 0.5 0.28 10.2 0.0 4.1 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.27 EPY54275.1 - 2.8e-28 96.7 8.3 4.2e-08 32.7 0.0 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EPY54275.1 - 2.3e-05 24.0 0.0 0.0019 17.7 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.6 EPY54275.1 - 5.5e-05 22.9 0.1 1.7 8.3 0.0 3.4 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ PF01011.16 EPY54275.1 - 0.0006 19.2 0.6 0.19 11.3 0.1 3.9 4 0 0 4 4 4 1 PQQ enzyme repeat DNA_ligase_A_M PF01068.16 EPY54276.1 - 5.3e-54 182.6 0.1 1.1e-53 181.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPY54276.1 - 6.7e-38 130.2 0.0 1.5e-37 129.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPY54276.1 - 1.1e-17 64.1 0.0 2.5e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DUF2052 PF09747.4 EPY54276.1 - 0.044 13.7 0.2 0.044 13.7 0.1 2.2 1 1 1 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1401 PF07180.6 EPY54276.1 - 0.088 12.5 0.0 0.53 10.0 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1401) Metallophos PF00149.23 EPY54277.1 - 1.4e-06 27.9 1.6 3.1e-06 26.7 1.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TOM13 PF08219.6 EPY54278.1 - 1.4e-17 63.2 0.1 1.6e-17 63.0 0.1 1.0 1 0 0 1 1 1 1 Outer membrane protein TOM13 Exonuc_VII_S PF02609.11 EPY54279.1 - 0.00031 20.4 5.0 0.00031 20.4 3.5 3.8 4 0 0 4 4 4 1 Exonuclease VII small subunit Surfac_D-trimer PF09006.6 EPY54279.1 - 0.036 13.7 0.2 0.036 13.7 0.1 2.4 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Pam16 PF03656.8 EPY54280.1 - 1.4e-31 108.9 0.5 1.6e-31 108.6 0.4 1.0 1 0 0 1 1 1 1 Pam16 Pmp3 PF01679.12 EPY54281.1 - 1.5e-25 88.5 6.8 1.7e-25 88.4 4.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SE PF08491.5 EPY54282.1 - 1.5e-107 358.5 0.0 2e-107 358.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EPY54282.1 - 1.5e-09 37.4 0.0 1.4e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPY54282.1 - 2.2e-08 33.4 0.0 4.3e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPY54282.1 - 4.1e-05 22.6 1.2 0.005 15.7 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EPY54282.1 - 8.9e-05 22.4 0.7 0.00029 20.8 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPY54282.1 - 0.00017 20.5 0.1 0.1 11.4 0.1 2.0 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EPY54282.1 - 0.00027 20.0 0.3 0.00083 18.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family GDI PF00996.13 EPY54282.1 - 0.0014 17.0 0.0 0.0021 16.4 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.22 EPY54282.1 - 0.0024 18.2 0.5 0.0057 17.0 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EPY54282.1 - 0.012 15.0 0.2 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EPY54282.1 - 0.028 14.2 0.1 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPY54282.1 - 0.03 13.2 0.1 0.21 10.4 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EPY54282.1 - 0.041 12.9 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EPY54282.1 - 0.048 13.7 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EPY54282.1 - 0.12 12.4 0.5 1.1 9.2 0.1 2.4 2 1 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 EPY54282.1 - 0.2 10.0 0.3 0.35 9.2 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein SMK-1 PF04802.10 EPY54283.1 - 2.4e-73 245.7 6.2 2.4e-73 245.7 4.3 2.0 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Mcp5_PH PF12814.2 EPY54284.1 - 3.6e-25 88.2 0.2 9.3e-25 86.9 0.2 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology BRE1 PF08647.6 EPY54284.1 - 0.81 9.6 19.4 2.3 8.2 5.8 3.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HALZ PF02183.13 EPY54284.1 - 0.99 9.1 11.8 0.18 11.5 1.2 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Rotamase PF00639.16 EPY54284.1 - 4.2 8.1 9.3 9.6 7.0 0.9 3.6 3 0 0 3 3 3 0 PPIC-type PPIASE domain NAD_binding_10 PF13460.1 EPY54285.1 - 1.7e-21 77.0 0.0 2.2e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPY54285.1 - 8.5e-07 28.6 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPY54285.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.8 EPY54285.1 - 0.042 13.1 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EPY54285.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain SelR PF01641.13 EPY54286.1 - 8.7e-50 167.5 0.1 1.1e-49 167.2 0.1 1.1 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.7 EPY54286.1 - 0.0093 15.2 0.5 0.83 9.0 0.1 2.5 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 EPY54286.1 - 0.02 14.7 1.6 0.21 11.4 1.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 EPY54286.1 - 0.05 13.3 2.5 2.2 8.0 0.1 2.8 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) NOB1_Zn_bind PF08772.6 EPY54286.1 - 0.37 10.6 2.7 0.75 9.6 0.2 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like HNH_5 PF14279.1 EPY54286.1 - 0.64 10.0 3.0 12 6.0 2.1 2.3 1 1 0 1 1 1 0 HNH endonuclease PI3_PI4_kinase PF00454.22 EPY54287.1 - 3.1e-59 200.3 0.1 6.5e-59 199.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EPY54287.1 - 8.7e-39 133.4 8.2 1.4e-38 132.7 5.7 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EPY54287.1 - 1.2e-21 76.6 1.3 1.1e-20 73.5 0.0 3.4 3 1 1 4 4 4 1 UME (NUC010) domain FATC PF02260.15 EPY54287.1 - 5.3e-14 51.3 0.0 1.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_16 PF13432.1 EPY54287.1 - 7.1e-07 29.7 0.5 0.083 13.5 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPY54287.1 - 0.0058 16.2 3.1 4 7.1 0.0 3.5 3 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EPY54287.1 - 0.035 14.4 0.1 0.54 10.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPY54287.1 - 0.047 13.6 2.1 7.8 6.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPY54287.1 - 0.072 13.7 1.3 4.8 8.0 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPY54287.1 - 0.082 13.4 0.3 0.53 10.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPY54287.1 - 0.29 11.0 3.4 10 6.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPY54287.1 - 2.2 8.2 7.6 16 5.5 0.2 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat TIMELESS PF04821.9 EPY54288.1 - 1.2e-64 218.1 4.9 1.2e-64 218.1 3.4 2.4 2 0 0 2 2 2 2 Timeless protein FAT PF02259.18 EPY54289.1 - 2.1e-121 405.2 12.3 2.1e-121 405.2 8.6 3.1 3 1 0 3 3 3 1 FAT domain DUF3385 PF11865.3 EPY54289.1 - 2.7e-61 206.1 3.4 6.1e-61 205.0 0.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EPY54289.1 - 1.1e-60 205.0 0.2 1.8e-60 204.3 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EPY54289.1 - 9.3e-43 144.3 1.5 1.9e-42 143.3 0.0 2.5 2 0 0 2 2 2 1 Rapamycin binding domain FATC PF02260.15 EPY54289.1 - 1e-15 56.8 0.5 2.7e-15 55.4 0.4 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EPY54289.1 - 6.7e-14 51.9 13.9 0.00075 19.7 0.0 10.2 6 2 5 11 11 11 5 HEAT repeats HEAT PF02985.17 EPY54289.1 - 3.3e-13 48.5 15.7 0.25 11.5 0.0 11.0 12 0 0 12 12 10 4 HEAT repeat HEAT_EZ PF13513.1 EPY54289.1 - 6.7e-09 35.9 22.3 0.0016 18.9 0.0 12.8 14 1 2 16 16 15 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPY54289.1 - 0.00041 20.6 2.4 1.4 9.3 0.0 5.7 6 1 2 8 8 7 1 Vacuolar 14 Fab1-binding region Apc3 PF12895.2 EPY54289.1 - 0.002 18.2 4.4 0.83 9.8 0.3 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPY54289.1 - 0.014 15.1 1.2 6 6.9 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPY54289.1 - 3.3 7.8 8.0 14 5.8 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_12 PF13087.1 EPY54290.1 - 1.6e-05 24.3 0.1 7.1e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPY54290.1 - 0.0067 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPY54290.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Amidase PF01425.16 EPY54291.1 - 1.1e-108 364.0 0.0 1.2e-108 363.8 0.0 1.0 1 0 0 1 1 1 1 Amidase PAP_central PF04928.12 EPY54292.1 - 1.2e-106 355.2 0.1 2.2e-106 354.3 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EPY54292.1 - 2.6e-52 176.5 0.7 2.6e-52 176.5 0.5 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EPY54292.1 - 5.1e-11 42.7 0.1 1.8e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain SQS_PSY PF00494.14 EPY54293.1 - 4.6e-41 140.8 0.0 5.8e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Terminase_4 PF05119.7 EPY54293.1 - 0.025 14.7 0.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit Glyco_hydro_71 PF03659.9 EPY54294.1 - 4.6e-98 328.2 13.4 5.3e-98 328.0 9.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Steroid_dh PF02544.11 EPY54295.1 - 2.2e-43 147.5 8.0 2.2e-43 147.5 5.5 1.4 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EPY54295.1 - 3.6e-06 26.2 0.0 9.7e-06 24.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family PEMT PF04191.8 EPY54295.1 - 0.019 15.0 0.2 0.045 13.8 0.1 1.7 1 0 0 1 1 1 0 Phospholipid methyltransferase Rad60-SLD PF11976.3 EPY54295.1 - 0.025 14.2 0.0 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TMEM107 PF14995.1 EPY54295.1 - 0.027 14.5 1.7 0.055 13.6 1.2 1.5 1 0 0 1 1 1 0 Transmembrane protein DUF1295 PF06966.7 EPY54295.1 - 0.067 12.4 4.8 0.021 14.1 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Oxysterol_BP PF01237.13 EPY54296.1 - 5.8e-53 179.6 0.0 4.1e-42 143.9 0.1 2.4 2 1 0 2 2 2 2 Oxysterol-binding protein eIF3_N PF09440.5 EPY54297.1 - 1.1e-49 168.0 7.2 2.8e-49 166.6 2.1 2.4 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EPY54297.1 - 0.0003 21.0 0.3 0.0012 19.1 0.2 2.1 1 0 0 1 1 1 1 PCI domain IF2_N PF04760.10 EPY54297.1 - 0.0016 18.0 1.1 0.16 11.6 0.0 3.7 3 1 0 3 3 3 1 Translation initiation factor IF-2, N-terminal region PCI_Csn8 PF10075.4 EPY54297.1 - 0.0069 16.1 0.2 0.017 14.8 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Mito_fiss_reg PF05308.6 EPY54297.1 - 0.038 13.3 1.1 0.07 12.4 0.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator BAR_3_WASP_bdg PF10456.4 EPY54297.1 - 0.051 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Nop PF01798.13 EPY54298.1 - 4.6e-59 198.0 0.0 8.3e-59 197.1 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPY54298.1 - 1.5e-26 91.9 0.2 3.7e-26 90.6 0.2 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPY54298.1 - 9.3e-22 76.9 0.3 9.3e-22 76.9 0.2 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain SMP_2 PF10144.4 EPY54298.1 - 0.015 14.4 0.1 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin RNA_polI_A34 PF08208.6 EPY54298.1 - 1.5 8.4 33.8 3.7 7.1 23.5 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TFIIF_alpha PF05793.7 EPY54298.1 - 4.2 5.6 32.9 5.9 5.1 22.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cpn60_TCP1 PF00118.19 EPY54299.1 - 1.7e-146 488.7 1.2 1.9e-146 488.5 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lin0512_fam PF09585.5 EPY54299.1 - 0.099 12.2 0.4 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) RasGAP PF00616.14 EPY54300.1 - 9.4e-46 155.9 0.4 9.4e-46 155.9 0.2 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EPY54300.1 - 5.7e-19 68.2 2.2 2.2e-18 66.3 1.5 2.1 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 EPY54300.1 - 0.0076 16.5 0.6 2.2 8.6 0.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF972) CBS PF00571.23 EPY54301.1 - 2e-19 69.0 0.1 1.6e-06 27.7 0.0 4.4 4 0 0 4 4 4 4 CBS domain ORC5_C PF14630.1 EPY54302.1 - 2.2e-68 230.6 0.2 2.9e-68 230.2 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EPY54302.1 - 9.8e-07 28.9 0.1 1.9e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPY54302.1 - 4.4e-06 26.8 0.0 8.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPY54302.1 - 6.1e-05 22.9 0.1 0.00015 21.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPY54302.1 - 0.083 12.5 0.1 0.3 10.7 0.1 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EPY54302.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pex16 PF08610.5 EPY54303.1 - 2.8e-45 154.7 8.8 3.6e-45 154.4 6.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Proteasome PF00227.21 EPY54304.1 - 4.3e-46 156.6 0.0 5.7e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPY54304.1 - 1.6e-14 52.9 0.1 2.5e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 EPY54305.1 - 6.3e-19 67.0 9.5 5.5e-05 22.8 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Ecl1 PF12855.2 EPY54306.1 - 0.00015 21.0 6.8 0.00032 19.9 4.7 1.8 1 1 0 1 1 1 1 Life-span regulatory factor zf-NF-X1 PF01422.12 EPY54306.1 - 0.086 12.8 4.7 0.086 12.8 3.3 1.6 2 0 0 2 2 2 0 NF-X1 type zinc finger HlyIII PF03006.15 EPY54307.1 - 0.12 11.7 4.8 0.14 11.5 3.4 1.0 1 0 0 1 1 1 0 Haemolysin-III related PITH PF06201.8 EPY54308.1 - 1.8e-37 128.4 0.0 2.2e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain Shugoshin_C PF07557.6 EPY54309.1 - 7.7e-05 22.0 1.7 7.7e-05 22.0 1.2 2.0 2 0 0 2 2 2 1 Shugoshin C terminus Pkinase PF00069.20 EPY54311.1 - 7.3e-35 120.3 0.0 9.8e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPY54311.1 - 8e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPY54311.1 - 0.00019 21.2 0.0 0.0045 16.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Nucleoporin_N PF08801.6 EPY54312.1 - 6.1e-25 87.8 0.1 1.2e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 EPY54312.1 - 4.8e-24 84.8 16.2 6.5e-24 84.3 11.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal TPP_enzyme_N PF02776.13 EPY54313.1 - 7.3e-56 188.3 0.1 6.4e-55 185.2 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPY54313.1 - 3.1e-50 169.7 0.0 1.2e-48 164.5 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPY54313.1 - 8.4e-40 135.7 0.0 1.5e-38 131.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EPY54313.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit zf-CCHC PF00098.18 EPY54314.1 - 4.8e-06 26.2 33.1 2.8e-05 23.8 2.5 4.9 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.1 EPY54314.1 - 0.021 14.4 29.9 0.034 13.8 0.2 5.4 4 1 1 5 5 5 0 Zinc knuckle ComC PF03047.9 EPY54314.1 - 0.065 12.6 0.2 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 COMC family DUF1356 PF07092.7 EPY54314.1 - 0.15 11.2 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) zf-CCHC_6 PF15288.1 EPY54314.1 - 0.19 11.4 23.7 0.11 12.2 1.2 4.1 1 1 3 4 4 4 0 Zinc knuckle zf-U1 PF06220.7 EPY54315.1 - 1.6e-22 78.7 1.3 3e-22 77.8 0.9 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EPY54315.1 - 0.13 12.4 0.5 0.13 12.4 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.18 EPY54316.1 - 3.9e-57 193.3 1.2 6.6e-57 192.5 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPY54316.1 - 6.9e-15 54.6 0.0 1.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPY54316.1 - 2.8e-14 52.6 1.0 2.8e-14 52.6 0.7 2.0 1 1 1 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EPY54316.1 - 2e-05 24.1 8.3 2e-05 24.1 5.8 2.7 3 0 0 3 3 3 1 PHD-finger Chromo PF00385.19 EPY54316.1 - 3.6e-05 23.3 4.6 0.0054 16.3 1.2 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.1 EPY54316.1 - 0.073 12.3 11.7 0.42 9.8 4.5 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Cytochrom_CIII PF02085.11 EPY54316.1 - 0.24 11.5 7.3 0.54 10.3 5.0 1.5 1 0 0 1 1 1 0 Class III cytochrome C family ZZ PF00569.12 EPY54317.1 - 4.2e-23 80.6 45.8 2.2e-11 43.1 6.9 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_3 PF07649.7 EPY54317.1 - 0.027 14.4 41.2 0.53 10.3 5.2 3.6 3 0 0 3 3 3 0 C1-like domain Baculo_IE-1 PF05290.6 EPY54317.1 - 3.4 7.3 25.0 0.07 12.8 3.7 3.3 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) NUDIX PF00293.23 EPY54318.1 - 7e-15 54.8 0.0 1.3e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain YL1 PF05764.8 EPY54319.1 - 1.1e-35 123.4 30.4 1.4e-35 123.0 21.1 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 EPY54319.1 - 1.5e-10 40.4 0.1 4.8e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain PUF PF00806.14 EPY54320.1 - 1.7e-18 64.9 0.0 0.0009 18.6 0.0 4.7 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EPY54320.1 - 9.9e-11 41.1 0.0 2.1e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPY54320.1 - 1.7e-07 31.0 0.1 4.7e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPY54320.1 - 1.2e-05 25.0 0.1 4.2e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med15_fungi PF05397.7 EPY54321.1 - 2.4e-29 101.6 2.3 2.4e-29 101.6 1.6 4.7 5 1 1 6 6 6 1 Mediator complex subunit 15 PEX11 PF05648.9 EPY54321.1 - 2.3 7.4 7.2 2.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) SMC_N PF02463.14 EPY54323.1 - 4.9e-73 245.0 33.7 9.9e-37 126.2 7.9 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPY54323.1 - 1.3e-27 96.1 0.4 4.5e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EPY54323.1 - 1.5e-15 58.0 1.3 1.5e-15 58.0 0.9 6.4 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EPY54323.1 - 8.3e-08 32.5 45.0 0.0036 17.3 11.5 4.5 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPY54323.1 - 2.5e-05 23.7 0.0 6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain IncA PF04156.9 EPY54323.1 - 0.00017 21.2 11.1 0.00017 21.2 7.7 7.0 2 2 4 6 6 6 1 IncA protein ATG16 PF08614.6 EPY54323.1 - 0.0008 19.2 15.8 0.0008 19.2 10.9 7.7 2 2 4 7 7 7 3 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EPY54323.1 - 0.0025 16.5 17.1 0.0025 16.5 11.8 6.4 2 2 5 7 7 7 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EPY54323.1 - 0.0038 16.4 2.4 0.0038 16.4 1.7 5.8 2 2 4 6 6 6 2 Reovirus sigma C capsid protein FUSC PF04632.7 EPY54323.1 - 5.8 5.2 9.9 0.32 9.3 0.0 2.6 2 1 0 2 2 2 0 Fusaric acid resistance protein family RVP PF00077.15 EPY54324.1 - 0.0011 18.8 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease NTF2 PF02136.15 EPY54324.1 - 0.044 14.1 0.2 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain rve PF00665.21 EPY54325.1 - 5.5e-25 87.8 0.0 8.8e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain