# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Aminotran_5 PF00266.19 KEZ38580.1 - 4.4e-90 302.3 0.0 5.3e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ38580.1 - 8.3e-07 28.6 0.0 9.5e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KEZ38580.1 - 5.1e-06 26.1 0.0 8.4e-05 22.0 0.0 2.6 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KEZ38580.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KEZ38580.1 - 0.03 12.9 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-C4 PF00105.18 KEZ38580.1 - 0.15 12.6 0.3 0.35 11.3 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) BAR PF03114.18 KEZ38581.1 - 8.5e-64 215.5 5.9 1.1e-63 215.0 5.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KEZ38581.1 - 1.3e-14 53.5 0.1 2.6e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ38581.1 - 7.2e-12 45.0 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEZ38581.1 - 1.6e-08 34.1 0.1 5.3e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain TMPIT PF07851.13 KEZ38581.1 - 0.055 12.7 5.7 0.33 10.1 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Rota_NSP4 PF01452.16 KEZ38581.1 - 0.089 12.5 0.3 0.57 9.8 0.0 2.3 2 1 1 3 3 3 0 Rotavirus non structural protein APG6_N PF17675.1 KEZ38581.1 - 3.2 8.3 14.7 1.9 9.0 7.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region F-box-like PF12937.7 KEZ38582.1 - 0.0013 18.5 0.1 0.0031 17.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ38582.1 - 0.0072 16.2 0.0 0.0072 16.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KEZ38582.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box ADIP PF11559.8 KEZ38583.1 - 7.4e-41 139.8 7.5 2.7e-40 137.9 7.5 2.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 KEZ38583.1 - 0.00051 19.6 4.8 0.00051 19.6 4.8 3.0 3 0 0 3 3 3 1 Golgin subfamily A member 5 PhoU PF01895.19 KEZ38583.1 - 0.066 13.7 1.0 1.5 9.3 0.0 3.3 2 1 1 3 3 3 0 PhoU domain Spc7 PF08317.11 KEZ38583.1 - 0.1 11.4 6.9 0.36 9.7 6.9 1.9 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 KEZ38583.1 - 0.16 11.7 2.5 4.5 7.1 0.4 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 DegS PF05384.11 KEZ38583.1 - 0.39 10.2 6.3 1.2 8.6 4.0 2.6 2 0 0 2 2 2 0 Sensor protein DegS Prominin PF05478.11 KEZ38583.1 - 0.43 8.5 3.1 0.87 7.5 3.1 1.4 1 0 0 1 1 1 0 Prominin HR1 PF02185.16 KEZ38583.1 - 1.7 8.8 8.5 9.8 6.4 8.5 2.4 1 1 0 1 1 1 0 Hr1 repeat Macoilin PF09726.9 KEZ38583.1 - 2 6.9 18.0 0.016 13.8 3.3 2.2 2 0 0 2 2 2 0 Macoilin family TPR_1 PF00515.28 KEZ38584.1 - 0.13 12.2 1.4 1.2 9.1 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 KEZ38584.1 - 0.26 11.8 0.6 1.3e+02 3.2 0.0 4.7 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KEZ38585.1 - 2e-50 171.7 0.0 2.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38585.1 - 3.4e-18 65.9 0.0 6.8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ38585.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pex24p PF06398.11 KEZ38586.1 - 6.9e-74 249.0 0.0 1.5e-73 247.9 0.0 1.5 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin SKG6 PF08693.10 KEZ38587.1 - 0.04 13.3 0.3 0.072 12.5 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GST_N_4 PF17172.4 KEZ38588.1 - 4.9e-17 62.5 0.0 1.1e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEZ38588.1 - 2.9e-11 43.0 0.0 5.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KEZ38588.1 - 3.6e-10 40.2 1.1 6.4e-10 39.4 1.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KEZ38588.1 - 0.0012 19.1 0.1 0.0028 17.9 0.1 1.6 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex SPRY PF00622.28 KEZ38589.1 - 1.8e-31 108.8 1.3 3e-31 108.0 1.3 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KEZ38589.1 - 3.7e-24 85.3 0.0 5.8e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KEZ38589.1 - 7.4e-06 25.7 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 LisH CbiZ PF01955.18 KEZ38589.1 - 0.048 13.8 0.3 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Adenosylcobinamide amidohydrolase INO80_Ies4 PF08193.11 KEZ38590.1 - 8.6e-62 209.3 23.8 8.6e-62 209.3 23.8 1.6 1 1 0 1 1 1 1 INO80 complex subunit Ies4 AA_permease_2 PF13520.6 KEZ38591.1 - 5.9e-56 190.1 53.5 3.5e-55 187.5 53.5 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ38591.1 - 6.8e-24 84.3 52.5 1.2e-22 80.1 52.5 2.0 1 1 0 1 1 1 1 Amino acid permease SLATT_5 PF18160.1 KEZ38591.1 - 0.031 13.6 0.5 0.031 13.6 0.5 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 peroxidase PF00141.23 KEZ38592.1 - 2.4e-82 276.0 0.0 5.7e-43 147.2 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Aldedh PF00171.22 KEZ38593.1 - 6.3e-186 618.4 0.0 7.1e-186 618.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.20 KEZ38594.1 - 4.2e-159 529.8 0.0 5.1e-159 529.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KEZ38594.1 - 2.7e-19 69.4 0.1 6e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KEZ38594.1 - 1.8e-15 57.0 0.2 3.4e-15 56.1 0.2 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Fungal_trans_2 PF11951.8 KEZ38595.1 - 7.9e-13 48.0 0.7 4.4e-08 32.4 0.1 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF2306 PF10067.9 KEZ38596.1 - 5e-17 62.5 9.3 5e-17 62.5 9.3 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Amidohydro_2 PF04909.14 KEZ38597.1 - 4e-25 89.2 0.4 5.1e-25 88.8 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase IDO PF01231.18 KEZ38598.1 - 6.7e-35 120.7 0.0 8.9e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPMT PF05724.11 KEZ38599.1 - 4.3e-31 108.3 0.0 1.2e-30 106.9 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KEZ38599.1 - 3.6e-07 30.1 0.0 9.4e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38599.1 - 1.7e-06 28.6 0.0 3.3e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38599.1 - 2.8e-06 27.9 0.0 6.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38599.1 - 3.5e-06 27.0 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38599.1 - 0.0019 18.9 0.0 0.0059 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KEZ38599.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB 3HCDH_N PF02737.18 KEZ38599.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEZ38599.1 - 0.084 13.1 0.0 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain Dicty_REP PF05086.12 KEZ38599.1 - 0.37 8.7 2.9 0.48 8.3 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Chitin_synth_1 PF01644.17 KEZ38600.1 - 2.3e-68 229.3 0.0 3.2e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KEZ38600.1 - 1.1e-27 95.7 0.0 3.4e-27 94.2 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KEZ38600.1 - 8.6e-26 90.6 0.1 5.3e-21 74.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KEZ38600.1 - 6.3e-09 36.0 0.0 6.3e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEZ38600.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Opy2 PF09463.10 KEZ38601.1 - 5.3 7.4 15.6 9 6.7 15.6 1.4 1 0 0 1 1 1 0 Opy2 protein YrhK PF14145.6 KEZ38602.1 - 0.68 9.8 29.0 0.31 11.0 0.6 4.8 3 2 1 4 4 4 0 YrhK-like protein Mcp5_PH PF12814.7 KEZ38603.1 - 1.5e-47 160.7 0.1 2.9e-47 159.8 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KEZ38603.1 - 1e-05 26.1 18.1 2.6e-05 24.8 18.1 1.6 1 0 0 1 1 1 1 Fez1 Atg14 PF10186.9 KEZ38603.1 - 0.0071 15.5 10.1 0.014 14.6 10.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 KEZ38603.1 - 0.033 14.3 27.5 1 9.4 21.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 KEZ38603.1 - 0.16 11.8 8.7 0.36 10.6 8.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KEZ38603.1 - 2.3 7.0 16.6 4.2 6.1 16.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 KEZ38603.1 - 2.6 7.8 30.7 0.0085 15.9 14.6 2.5 2 1 1 3 3 3 0 Ezrin/radixin/moesin family UQ_con PF00179.26 KEZ38604.1 - 2e-37 128.0 0.0 2.6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ38604.1 - 0.055 13.2 0.0 0.074 12.8 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B IlvN PF07991.12 KEZ38605.1 - 1.1e-46 158.4 0.0 1.7e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KEZ38605.1 - 3.1e-41 141.0 0.0 4.9e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 KEZ38605.1 - 0.096 13.3 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KEZ38605.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PALP PF00291.25 KEZ38606.1 - 1e-57 195.8 0.5 1.3e-57 195.5 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ThiP_synth PF10120.9 KEZ38606.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine-phosphate synthase F420_oxidored PF03807.17 KEZ38606.1 - 0.083 13.5 1.3 2.2 8.9 0.1 2.8 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Transglut_core PF01841.19 KEZ38606.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily MFS_1 PF07690.16 KEZ38607.1 - 1.1e-39 136.4 45.6 2.9e-39 135.0 39.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ38607.1 - 0.00011 21.7 3.9 0.00011 21.7 3.9 2.6 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB RseC_MucC PF04246.12 KEZ38607.1 - 3.1 7.8 10.5 1 9.3 0.1 3.5 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Zip PF02535.22 KEZ38607.1 - 5.4 6.1 9.6 0.072 12.3 1.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.14 KEZ38607.1 - 5.9 5.1 6.2 8.6 4.5 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 KEZ38607.1 - 9.1 6.7 9.4 1.7 9.1 4.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldedh PF00171.22 KEZ38608.1 - 4.5e-15 55.1 8.7 2.2e-09 36.4 6.7 2.7 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 KEZ38608.1 - 0.035 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) BRCT_2 PF16589.5 KEZ38609.1 - 7e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KEZ38609.1 - 5.1e-05 23.1 0.5 0.00028 20.8 0.0 2.3 3 0 0 3 3 3 1 twin BRCT domain BRCT PF00533.26 KEZ38609.1 - 0.00077 19.8 0.0 0.0034 17.7 0.0 2.1 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain AMP-binding PF00501.28 KEZ38610.1 - 7.7e-70 235.6 0.0 1e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ38610.1 - 3.6e-18 66.3 1.1 8.7e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KEZ38610.1 - 8.6e-18 64.0 1.2 1.5e-17 63.2 0.4 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Pkinase PF00069.25 KEZ38611.1 - 4.7e-12 45.8 0.5 3.4e-11 43.0 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38611.1 - 0.0094 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N PF00107.26 KEZ38612.1 - 2.3e-26 92.3 0.2 3.9e-26 91.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ38612.1 - 1.1e-24 88.0 0.1 1.9e-24 87.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ38612.1 - 1.7e-08 34.3 0.0 2.9e-07 30.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2828 PF11443.8 KEZ38612.1 - 0.24 9.4 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) KilA-N PF04383.13 KEZ38613.1 - 0.00078 19.3 0.0 0.013 15.3 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Flocculin_t3 PF13928.6 KEZ38614.1 - 0.051 14.1 8.7 0.051 14.1 8.7 3.7 2 2 1 3 3 3 0 Flocculin type 3 repeat DLH PF01738.18 KEZ38615.1 - 2.4e-17 63.2 0.2 1.9e-16 60.3 0.2 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Rep_fac-A_C PF08646.10 KEZ38616.1 - 5.5e-48 162.4 3.7 2e-46 157.3 2.8 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KEZ38616.1 - 4.3e-37 126.0 1.1 3.7e-36 123.0 0.3 2.8 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 KEZ38616.1 - 7.1e-19 67.7 0.1 2.5e-18 65.9 0.0 2.0 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KEZ38616.1 - 3.2e-14 52.7 0.2 4.7e-10 39.3 0.0 3.9 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KEZ38616.1 - 0.00032 20.5 0.8 0.99 9.1 0.3 2.9 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 POT1 PF02765.17 KEZ38616.1 - 0.0071 16.2 1.0 0.15 11.9 0.0 3.0 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 DUF223 PF02721.14 KEZ38616.1 - 0.11 12.8 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 PCI PF01399.27 KEZ38617.1 - 0.058 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 PCI domain CENP-Q PF13094.6 KEZ38617.1 - 0.14 12.3 3.6 0.094 12.9 1.3 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_14 PF13428.6 KEZ38617.1 - 1.6 9.7 5.3 16 6.7 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat zf-PHD-like PF15446.6 KEZ38619.1 - 1.7e-65 219.8 13.2 1.7e-65 219.8 13.2 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KEZ38619.1 - 5.4e-49 166.8 0.3 5.4e-49 166.8 0.3 2.6 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ38619.1 - 5.4e-18 65.4 2.1 1.1e-17 64.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KEZ38619.1 - 1.4e-10 40.9 0.3 1.4e-10 40.9 0.3 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KEZ38619.1 - 1.9e-05 24.5 4.2 6.5e-05 22.8 0.0 3.7 4 0 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KEZ38619.1 - 6.6e-05 22.7 4.9 6.6e-05 22.7 4.9 3.3 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 KEZ38619.1 - 0.013 15.1 1.1 0.013 15.1 1.1 3.0 3 0 0 3 3 3 0 PHD-finger Zf_RING PF16744.5 KEZ38619.1 - 3.3 7.9 13.7 7.6 6.7 0.3 2.9 2 1 0 2 2 2 0 KIAA1045 RING finger DUF2318 PF10080.9 KEZ38619.1 - 9 6.5 8.6 0.42 10.7 1.5 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) DUF1365 PF07103.11 KEZ38621.1 - 6.1e-37 127.6 0.0 3.1e-27 95.8 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1365) GFA PF04828.14 KEZ38622.1 - 8.6e-24 83.7 0.0 1.2e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KEZ38622.1 - 0.41 10.7 3.8 2.9 8.0 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon MBF1 PF08523.10 KEZ38623.1 - 2.9e-22 78.9 0.9 6e-22 77.9 0.9 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KEZ38623.1 - 8.2e-11 41.8 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KEZ38623.1 - 0.001 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 KEZ38623.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GST_N_3 PF13417.6 KEZ38624.1 - 7.6e-12 45.5 0.1 1.6e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEZ38624.1 - 3.5e-06 27.2 0.0 7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ38624.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MIS13 PF08202.11 KEZ38625.1 - 2.3e-57 194.6 2.1 2.3e-57 194.6 2.1 2.2 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Aft1_HRR PF11787.8 KEZ38625.1 - 5.7e-26 91.5 3.6 5.7e-26 91.5 3.6 5.0 6 0 0 6 6 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 KEZ38625.1 - 9e-24 83.6 8.8 5.8e-23 81.0 8.8 2.5 1 0 0 1 1 1 1 Aft1 HRA domain Aft1_OSA PF11785.8 KEZ38625.1 - 1.6e-21 76.4 5.5 1.6e-21 76.4 5.5 4.7 5 0 0 5 5 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KEZ38625.1 - 1.1e-11 44.7 7.3 1.1e-11 44.7 7.3 4.1 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 KEZ38625.1 - 1e-05 25.5 8.2 1e-05 25.5 8.2 3.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEZ38625.1 - 0.0056 17.2 5.1 0.0056 17.2 5.1 3.2 3 0 0 3 3 3 1 bZIP Maf transcription factor ZapB PF06005.12 KEZ38625.1 - 0.93 10.0 17.6 0.35 11.3 1.0 3.6 3 0 0 3 3 3 0 Cell division protein ZapB MbeD_MobD PF04899.12 KEZ38625.1 - 5.6 7.2 10.6 6.6 6.9 1.1 3.5 4 0 0 4 4 4 0 MbeD/MobD like HALZ PF02183.18 KEZ38625.1 - 5.8 7.2 7.0 0.19 11.9 0.3 2.0 2 0 0 2 2 1 0 Homeobox associated leucine zipper SlyX PF04102.12 KEZ38625.1 - 8.6 7.1 7.5 23 5.7 0.1 3.7 3 0 0 3 3 3 0 SlyX Sdh5 PF03937.16 KEZ38626.1 - 4.8e-24 84.1 0.3 3.1e-23 81.5 0.3 2.0 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase EMP24_GP25L PF01105.24 KEZ38627.1 - 9.6e-40 136.5 0.0 1.1e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 KEZ38627.1 - 0.066 11.4 0.8 0.088 11.0 0.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-U1 PF06220.12 KEZ38628.1 - 8.4e-22 76.7 3.4 1.3e-21 76.0 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger FAM75 PF14650.6 KEZ38628.1 - 0.46 10.0 1.8 0.74 9.3 1.8 1.3 1 0 0 1 1 1 0 FAM75 family Amidohydro_2 PF04909.14 KEZ38629.1 - 9.4e-24 84.7 0.0 2.1e-23 83.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Spt5-NGN PF03439.13 KEZ38629.1 - 0.078 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section HD PF01966.22 KEZ38630.1 - 1.2e-08 35.2 0.1 6.1e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 HD domain SUR7 PF06687.12 KEZ38632.1 - 2e-23 83.1 14.3 2e-23 83.1 14.3 1.7 2 0 0 2 2 2 1 SUR7/PalI family Ras PF00071.22 KEZ38633.1 - 1.5e-16 60.4 0.0 3.3e-15 56.1 0.0 2.7 2 1 0 2 2 2 1 Ras family Roc PF08477.13 KEZ38633.1 - 0.0025 18.0 0.0 0.016 15.4 0.0 2.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ38633.1 - 0.011 15.2 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DLIC PF05783.11 KEZ38633.1 - 0.018 13.9 0.0 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KEZ38633.1 - 0.026 14.9 0.5 0.051 14.0 0.1 1.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KEZ38633.1 - 0.041 14.1 2.0 0.4 10.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEZ38633.1 - 0.11 12.9 0.1 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KEZ38633.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TRP PF06011.12 KEZ38634.1 - 2.9e-161 537.0 33.9 3.6e-161 536.7 33.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEZ38634.1 - 5.9e-40 136.8 0.5 1e-39 136.1 0.5 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 KEZ38634.1 - 0.029 14.8 0.2 0.053 13.9 0.2 1.4 1 0 0 1 1 1 0 ML domain AIM24 PF01987.17 KEZ38635.1 - 1.4e-48 165.4 0.6 1.7e-48 165.1 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ndc1_Nup PF09531.10 KEZ38635.1 - 0.1 11.2 0.4 0.1 11.3 0.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med1 PF10744.9 KEZ38636.1 - 1.3e-107 360.4 0.0 1.6e-107 360.2 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 KEZ38637.1 - 4.7e-41 140.9 0.0 4.3e-40 137.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38637.1 - 1.5e-22 80.2 0.0 7.1e-22 77.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase GCP_C_terminal PF04130.13 KEZ38638.1 - 5.4e-99 331.6 0.0 8.7e-99 330.9 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEZ38638.1 - 4.4e-84 282.7 0.0 9e-84 281.7 0.0 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal tRNA-synt_1d PF00750.19 KEZ38638.1 - 0.11 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) SAGA-Tad1 PF12767.7 KEZ38639.1 - 1.3e-61 208.3 0.0 1.7e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit cNMP_binding PF00027.29 KEZ38640.1 - 4e-40 135.8 0.0 4e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KEZ38640.1 - 1e-06 28.3 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit BCAS2 PF05700.11 KEZ38641.1 - 1.7e-46 158.6 0.2 1.9e-46 158.3 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.8 KEZ38641.1 - 0.015 15.5 0.4 0.025 14.8 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HABP4_PAI-RBP1 PF04774.15 KEZ38642.1 - 0.00025 21.9 2.2 0.00038 21.3 2.2 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RNase_3_N PF18497.1 KEZ38642.1 - 0.2 11.9 0.1 0.27 11.5 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain TPR_12 PF13424.6 KEZ38643.1 - 4.8e-11 42.8 0.9 0.00012 22.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ38643.1 - 1.3e-06 28.0 3.7 0.0027 17.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ38643.1 - 4.4e-06 26.4 3.0 0.0019 18.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ38643.1 - 1.1e-05 25.1 0.1 0.14 12.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ38643.1 - 0.00033 20.6 1.1 0.098 12.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ38643.1 - 0.0032 17.3 0.6 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Sel1 PF08238.12 KEZ38643.1 - 0.16 12.7 0.7 1.6 9.6 0.2 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_14 PF13428.6 KEZ38643.1 - 0.24 12.3 1.2 68 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.28 KEZ38644.1 - 1.3e-85 287.6 0.0 1.6e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ38644.1 - 1.9e-13 51.2 0.1 4.5e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CDC50 PF03381.15 KEZ38645.1 - 7.8e-96 320.9 0.0 9.6e-96 320.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.11 KEZ38646.1 - 5.1e-56 189.0 0.1 5.1e-56 189.0 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KEZ38646.1 - 7.1e-54 182.0 0.5 2.6e-53 180.1 0.5 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KEZ38646.1 - 7.9e-25 87.8 0.0 1.9e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KEZ38646.1 - 6.6e-16 58.5 0.4 1.9e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RecQ5 PF06959.11 KEZ38646.1 - 0.045 13.7 0.4 0.079 12.9 0.4 1.3 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) Cyt-b5 PF00173.28 KEZ38647.1 - 1.1e-11 44.7 0.1 1.3e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CMD PF02627.20 KEZ38648.1 - 4.9e-07 29.7 0.1 1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Aldo_ket_red PF00248.21 KEZ38649.1 - 1.3e-08 34.4 0.0 1.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 KEZ38650.1 - 2.1e-52 176.8 1.5 2.5e-52 176.6 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KEZ38650.1 - 0.017 15.9 0.1 0.03 15.1 0.1 1.5 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 KEZ38651.1 - 4.6e-55 186.5 0.0 6.2e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Response_reg PF00072.24 KEZ38652.1 - 4.5e-27 94.4 0.3 8.3e-27 93.6 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KEZ38652.1 - 4.8e-27 94.7 1.8 2.7e-24 85.8 1.8 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KEZ38652.1 - 1.1e-14 54.2 0.0 2.3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KEZ38652.1 - 0.016 15.5 0.1 0.16 12.4 0.1 2.4 2 0 0 2 2 2 0 HAMP domain ORMDL PF04061.14 KEZ38653.1 - 6.2e-58 194.4 2.7 7.9e-58 194.1 2.7 1.1 1 0 0 1 1 1 1 ORMDL family Methyltransf_3 PF01596.17 KEZ38654.1 - 6.5e-34 117.0 0.0 1.1e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 KEZ38654.1 - 7e-15 55.3 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KEZ38654.1 - 6.5e-13 49.6 0.0 2.3e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38654.1 - 9.6e-13 48.2 0.0 1.6e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38654.1 - 2.6e-09 37.7 0.0 6.6e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38654.1 - 5.9e-05 23.6 0.0 0.00022 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38654.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 KEZ38654.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 KEZ38654.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 KEZ38654.1 - 0.016 16.0 0.0 0.036 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SUR7 PF06687.12 KEZ38656.1 - 7e-22 78.1 8.5 7.5e-22 78.0 7.7 1.4 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 KEZ38656.1 - 2.7e-06 27.3 3.8 2.7e-06 27.3 3.8 2.1 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction TraS PF10624.9 KEZ38656.1 - 0.0057 16.6 0.6 0.012 15.5 0.6 1.6 1 0 0 1 1 1 1 Plasmid conjugative transfer entry exclusion protein TraS LYRIC PF15686.5 KEZ38656.1 - 0.031 13.8 0.5 0.045 13.3 0.5 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF4064 PF13273.6 KEZ38656.1 - 0.096 13.0 12.9 0.033 14.5 6.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3177 PF11375.8 KEZ38656.1 - 0.85 9.4 6.4 0.075 12.8 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3177) Wzy_C PF04932.15 KEZ38656.1 - 0.92 9.1 5.1 1.3 8.6 3.4 1.9 2 0 0 2 2 2 0 O-Antigen ligase DUF1700 PF08006.11 KEZ38656.1 - 7.8 6.0 11.3 0.69 9.4 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Trp_oprn_chp PF09534.10 KEZ38656.1 - 9.4 6.0 7.3 3.6 7.4 2.6 2.4 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) ArsA_ATPase PF02374.15 KEZ38658.1 - 5.1e-112 374.0 0.0 5.9e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KEZ38658.1 - 1.4e-13 51.1 0.4 1.1e-12 48.2 0.0 2.4 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 KEZ38658.1 - 3.7e-12 46.4 0.0 1.1e-11 44.9 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KEZ38658.1 - 5e-07 29.4 0.6 0.00016 21.2 0.0 2.6 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KEZ38658.1 - 4e-06 26.6 0.8 0.00089 18.9 0.0 2.5 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 KEZ38658.1 - 1.9e-05 24.3 0.0 4.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KEZ38658.1 - 8.1e-05 22.2 0.0 0.00042 19.9 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_24 PF13479.6 KEZ38658.1 - 0.032 14.0 0.0 0.2 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEZ38658.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 KEZ38658.1 - 0.057 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KEZ38658.1 - 0.07 13.7 0.1 0.16 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KEZ38658.1 - 0.083 12.3 0.1 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KEZ38658.1 - 0.11 12.1 1.3 0.7 9.4 1.3 2.1 1 1 0 1 1 1 0 AAA domain MipZ PF09140.11 KEZ38658.1 - 0.22 10.8 0.2 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 ATPase MipZ DWNN PF08783.11 KEZ38659.1 - 4.2e-24 84.6 0.1 7.6e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KEZ38659.1 - 7.6e-09 35.2 7.1 2.5e-08 33.6 5.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 KEZ38659.1 - 3.7e-05 23.6 1.5 8.3e-05 22.5 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KEZ38659.1 - 0.0014 18.4 9.0 0.0014 18.4 9.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KEZ38659.1 - 0.0032 17.6 0.0 0.0083 16.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_5 PF14634.6 KEZ38659.1 - 0.01 15.7 5.6 0.01 15.7 5.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KEZ38659.1 - 0.019 15.3 6.2 0.045 14.1 6.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 KEZ38659.1 - 0.04 13.7 6.2 0.091 12.6 6.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CCHC_3 PF13917.6 KEZ38659.1 - 0.064 13.2 0.3 0.17 11.9 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4_4 PF15227.6 KEZ38659.1 - 0.089 13.0 9.6 0.28 11.4 9.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF966 PF06136.13 KEZ38659.1 - 0.096 12.4 10.4 0.013 15.2 5.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF966) zf-Nse PF11789.8 KEZ38659.1 - 0.18 11.7 5.3 0.38 10.6 5.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KEZ38659.1 - 0.39 10.8 6.4 0.8 9.8 6.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger HypA PF01155.19 KEZ38659.1 - 0.48 10.5 3.4 4.2 7.4 2.4 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4 PF00097.25 KEZ38659.1 - 0.68 9.8 8.9 1.4 8.9 8.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M20 PF01546.28 KEZ38660.1 - 9.1e-34 117.0 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ38660.1 - 1.8e-10 40.7 0.0 2.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.23 KEZ38661.1 - 3.1e-11 43.7 0.0 1.4e-10 41.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KEZ38661.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Choline_kinase PF01633.20 KEZ38661.1 - 0.018 14.6 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ODC_AZ PF02100.17 KEZ38662.1 - 9.4e-42 141.6 0.2 1.4e-41 141.0 0.2 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.21 KEZ38663.1 - 3.4e-50 170.7 0.3 1.4e-49 168.7 0.3 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KEZ38663.1 - 5.3e-20 72.0 0.0 8.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KEZ38663.1 - 3.5e-07 30.3 0.0 8.2e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KEZ38663.1 - 2e-05 24.3 0.0 5.6e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KEZ38663.1 - 0.061 13.1 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Dus PF01207.17 KEZ38663.1 - 0.15 11.1 0.0 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TFIIIC_sub6 PF10419.9 KEZ38664.1 - 1.4e-25 89.0 0.0 2.2e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Transformer PF06495.11 KEZ38665.1 - 0.054 13.6 0.6 0.054 13.6 0.6 1.9 2 0 0 2 2 2 0 Fruit fly transformer protein Ribosomal_L7Ae PF01248.26 KEZ38666.1 - 4.5e-23 80.8 0.0 5.1e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 KEZ38667.1 - 5.7e-44 149.3 0.0 7.2e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e TPR_MLP1_2 PF07926.12 KEZ38668.1 - 0.0096 16.0 23.5 0.0096 16.0 23.5 3.2 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein Peptidase_S28 PF05577.12 KEZ38668.1 - 0.091 11.5 2.0 0.14 11.0 2.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 TMPIT PF07851.13 KEZ38668.1 - 0.71 9.1 11.1 0.33 10.1 8.5 1.8 2 0 0 2 2 2 0 TMPIT-like protein CorA PF01544.18 KEZ38668.1 - 0.79 9.0 12.6 0.032 13.6 1.1 2.5 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 KEZ38668.1 - 5.1 7.3 16.4 2.3 8.4 5.9 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Sipho_Gp157 PF05565.11 KEZ38668.1 - 5.8 6.9 28.3 5.2 7.1 6.9 3.3 2 1 1 3 3 3 0 Siphovirus Gp157 Vac7 PF12751.7 KEZ38669.1 - 1.1e-146 489.2 5.4 1.1e-146 489.2 5.4 2.1 3 0 0 3 3 3 1 Vacuolar segregation subunit 7 PRP1_N PF06424.12 KEZ38670.1 - 1.2e-51 175.0 4.1 2.9e-51 173.8 4.1 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KEZ38670.1 - 8.8e-31 104.0 29.1 2.3e-05 24.8 0.1 14.1 4 3 10 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ38670.1 - 1.3e-29 102.5 15.6 5.9e-10 39.5 1.1 10.2 7 3 4 11 11 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ38670.1 - 1.7e-13 49.5 11.7 0.21 11.8 0.0 9.8 12 0 0 12 12 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ38670.1 - 5.5e-13 49.3 14.7 3.8e-05 24.2 0.5 7.8 6 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ38670.1 - 6.9e-13 48.0 3.2 1.9 9.1 0.0 9.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ38670.1 - 8.3e-12 44.3 2.6 0.83 10.0 0.0 8.7 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ38670.1 - 3.7e-08 32.9 1.6 0.29 11.0 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 KEZ38670.1 - 5.3e-08 32.2 10.9 0.075 11.9 0.0 6.4 4 2 2 6 6 6 3 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 KEZ38670.1 - 1.2e-06 28.4 12.3 0.02 14.6 2.3 5.1 3 1 1 4 4 4 3 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 KEZ38670.1 - 7.6e-06 25.3 29.7 0.0017 17.7 6.5 6.7 3 2 5 8 8 8 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KEZ38670.1 - 2.3e-05 24.4 1.4 1.6 8.6 0.2 4.2 3 1 1 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 KEZ38670.1 - 2.7e-05 24.2 12.0 0.13 12.4 0.0 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ38670.1 - 4.7e-05 23.0 9.2 0.11 12.2 0.1 6.3 6 0 0 6 6 6 1 TPR repeat TPR_6 PF13174.6 KEZ38670.1 - 0.00011 22.6 9.2 15 6.5 0.1 8.3 9 0 0 9 9 6 0 Tetratricopeptide repeat Suf PF05843.14 KEZ38670.1 - 0.00041 20.4 0.7 3.6 7.5 0.0 4.8 6 1 0 6 6 6 1 Suppressor of forked protein (Suf) DUF3808 PF10300.9 KEZ38670.1 - 0.0011 17.8 1.5 4.2 6.0 0.0 4.6 4 1 2 6 6 6 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 KEZ38670.1 - 0.0034 17.6 0.2 4.8 7.5 0.0 4.0 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KEZ38670.1 - 0.019 15.0 0.8 3.1 8.0 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 KEZ38670.1 - 0.035 14.1 0.2 9.8 6.2 0.0 3.8 3 0 0 3 3 3 0 ZNRF-3 Ectodomain CP12 PF02672.15 KEZ38670.1 - 0.071 13.9 0.6 0.071 13.9 0.6 2.8 3 0 0 3 3 1 0 CP12 domain NTP_transf_7 PF07984.12 KEZ38670.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase TPR_12 PF13424.6 KEZ38670.1 - 1.1 9.6 10.2 42 4.5 0.0 6.0 7 1 1 8 8 7 0 Tetratricopeptide repeat SMBP PF16785.5 KEZ38671.1 - 0.036 14.3 5.1 0.031 14.5 4.0 1.3 1 1 0 1 1 1 0 Small metal-binding protein DUF883 PF05957.13 KEZ38671.1 - 0.044 14.4 0.8 0.09 13.4 0.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2802 PF10975.8 KEZ38671.1 - 0.1 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) PP2C PF00481.21 KEZ38673.1 - 1.2e-82 277.5 0.0 1.7e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C ALAD PF00490.21 KEZ38674.1 - 7.7e-119 396.6 0.0 9.7e-119 396.2 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Amidohydro_3 PF07969.11 KEZ38676.1 - 2e-68 232.0 0.0 2.3e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KEZ38676.1 - 0.00065 19.1 0.0 0.03 13.6 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family 2Fe-2S_thioredx PF01257.19 KEZ38677.1 - 7.1e-58 194.6 0.0 9.3e-58 194.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin zf-C2H2 PF00096.26 KEZ38678.1 - 2e-08 34.3 25.9 0.00023 21.4 4.5 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ38678.1 - 2.9e-06 27.7 31.8 0.005 17.6 4.0 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEZ38678.1 - 7.3e-05 22.7 3.9 7.3e-05 22.7 3.9 3.9 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEZ38678.1 - 0.04 14.4 24.7 0.5 10.9 2.0 5.3 5 0 0 5 5 5 0 Zinc-finger double domain Vps36-NZF-N PF16988.5 KEZ38678.1 - 0.041 13.3 0.2 0.13 11.6 0.2 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ADK_lid PF05191.14 KEZ38678.1 - 3.2 7.8 6.3 10 6.2 0.0 2.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid TRAF6_Z2 PF18048.1 KEZ38678.1 - 4.2 7.5 6.0 9.3 6.4 0.7 3.6 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Nucleoporin_C PF03177.14 KEZ38680.1 - 2.5e-165 551.6 3.6 3.1e-165 551.3 3.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KEZ38680.1 - 3.7e-76 256.6 0.0 4.7e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 KEZ38681.1 - 4.5e-27 95.1 0.0 5.8e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38681.1 - 3.2e-14 52.8 0.0 4.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ38681.1 - 9.1e-07 28.0 0.0 1.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase HD_6 PF18019.1 KEZ38681.1 - 0.0068 16.6 0.2 0.011 15.9 0.2 1.2 1 0 0 1 1 1 1 HD domain APH PF01636.23 KEZ38681.1 - 0.14 12.1 0.0 0.87 9.5 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M44 PF03410.13 KEZ38681.1 - 0.21 10.1 0.0 0.3 9.6 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox EMP24_GP25L PF01105.24 KEZ38682.1 - 4.3e-51 173.4 0.0 4.9e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Hexapep_2 PF14602.6 KEZ38683.1 - 1.3e-14 53.7 17.5 4e-08 32.9 4.8 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 KEZ38683.1 - 5.2e-13 48.2 18.6 2.6e-06 26.9 1.9 3.9 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KEZ38683.1 - 1.9e-10 40.8 0.1 4.3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 KEZ38683.1 - 1.1e-09 38.2 7.9 2.4e-09 37.2 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KEZ38684.1 - 1.9e-27 94.9 31.0 1.2e-05 26.0 0.2 10.6 10 1 1 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ38684.1 - 2.5e-15 56.6 7.3 0.00021 21.5 0.1 6.6 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ38684.1 - 0.0011 18.0 4.8 0.54 9.2 0.0 4.5 3 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KEZ38684.1 - 0.0067 15.8 0.9 6.6 6.0 0.0 3.6 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KEZ38684.1 - 0.048 13.6 8.1 3.2 7.8 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KEZ38684.1 - 7.5 6.3 6.6 73 3.2 0.3 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Glyco_tran_28_C PF04101.16 KEZ38685.1 - 1.5e-17 64.1 0.0 6.3e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 KEZ38685.1 - 0.067 12.0 0.2 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase MRP-S28 PF10213.9 KEZ38686.1 - 1.9e-46 157.6 0.0 3.5e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein zf-MIZ PF02891.20 KEZ38687.1 - 9.3e-09 34.9 5.0 5.9e-06 25.9 5.0 2.4 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 KEZ38687.1 - 0.0061 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 PINIT domain CxC4 PF18717.1 KEZ38687.1 - 0.16 11.8 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases SAM_2 PF07647.17 KEZ38688.1 - 1.6e-13 50.5 0.0 3.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KEZ38688.1 - 5.1e-13 48.7 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ38688.1 - 8.5e-12 44.5 0.0 1.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KEZ38688.1 - 1.9e-08 34.7 0.0 5.9e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 KEZ38688.1 - 0.00012 21.7 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 KEZ38688.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KEZ38688.1 - 0.016 15.6 0.1 0.04 14.3 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain SAM_PNT PF02198.16 KEZ38688.1 - 0.083 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain MFS_MOT1 PF16983.5 KEZ38689.1 - 1.3e-58 196.2 33.6 2.2e-33 114.9 10.0 2.9 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily PS_Dcarbxylase PF02666.15 KEZ38690.1 - 1.2e-55 188.1 0.0 1.9e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KEZ38690.1 - 1e-35 122.1 0.0 7.8e-18 64.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 KEZ38690.1 - 0.0012 18.3 0.0 0.004 16.6 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEZ38690.1 - 0.19 11.7 1.5 0.6 10.2 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain LRR_6 PF13516.6 KEZ38692.1 - 0.00011 21.9 1.7 5.1 7.4 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich repeat CDC45 PF02724.14 KEZ38692.1 - 0.068 11.5 2.3 0.1 10.9 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 KEZ38692.1 - 8.2 6.0 20.7 19 4.7 20.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L5e PF17144.4 KEZ38694.1 - 2.1e-81 271.7 0.1 3.4e-81 271.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KEZ38694.1 - 1.6e-36 125.1 6.3 1.6e-36 125.1 6.3 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 KEZ38694.1 - 0.011 15.9 1.1 0.46 10.7 0.0 3.0 3 1 0 3 3 3 0 Threonine synthase N terminus HAD_2 PF13419.6 KEZ38695.1 - 0.0023 18.1 0.0 0.0055 16.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Coatomer_E PF04733.14 KEZ38696.1 - 8.1e-66 222.4 4.6 9.3e-66 222.2 4.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KEZ38696.1 - 1.1e-09 38.6 12.6 0.0039 17.7 0.2 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ38696.1 - 1.2e-06 28.9 8.6 0.034 15.0 0.1 5.0 4 1 1 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ38696.1 - 4.5e-06 26.8 0.2 0.23 11.7 0.0 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KEZ38696.1 - 1.5e-05 24.8 0.6 0.015 15.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ38696.1 - 0.0001 22.5 3.9 0.16 12.3 0.1 3.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ38696.1 - 0.00018 22.1 11.7 0.0052 17.4 0.1 4.6 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ38696.1 - 0.00027 20.6 0.1 0.025 14.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Arg_tRNA_synt_N PF03485.16 KEZ38696.1 - 0.00051 20.6 0.2 0.0015 19.1 0.2 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain TPR_4 PF07721.14 KEZ38696.1 - 0.0064 17.0 8.3 0.18 12.5 0.2 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 KEZ38696.1 - 0.011 16.0 2.3 3.5 7.9 0.6 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat Fis1_TPR_C PF14853.6 KEZ38696.1 - 0.012 15.7 0.1 3.9 7.6 0.1 3.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KEZ38696.1 - 0.012 15.6 0.0 0.012 15.6 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 KEZ38696.1 - 0.051 13.6 3.5 0.58 10.2 0.2 3.1 1 1 3 4 4 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_6 PF13174.6 KEZ38696.1 - 0.063 13.9 0.2 31 5.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SPOB_a PF14689.6 KEZ38696.1 - 0.1 12.3 0.2 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain ANAPC5 PF12862.7 KEZ38696.1 - 0.12 12.5 2.5 4.2 7.5 0.2 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KEZ38696.1 - 0.28 11.1 5.1 7.4 6.6 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ38696.1 - 0.29 11.3 3.9 16 5.8 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ38696.1 - 1 9.1 6.3 7.2 6.4 0.4 3.7 4 0 0 4 4 4 0 TPR repeat Acyl_transf_1 PF00698.21 KEZ38697.1 - 1.7e-19 70.5 0.8 9.9e-14 51.5 0.2 2.2 1 1 1 2 2 2 2 Acyl transferase domain Adap_comp_sub PF00928.21 KEZ38698.1 - 5.1e-66 222.7 0.0 6.9e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEZ38698.1 - 0.0057 16.6 0.0 0.0088 16.0 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ECR1_N PF14382.6 KEZ38699.1 - 5.6e-16 58.1 1.4 1.1e-15 57.2 1.4 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KEZ38699.1 - 4.8e-05 23.6 0.2 0.0001 22.5 0.2 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KEZ38699.1 - 0.008 16.8 0.2 0.25 12.0 0.1 2.6 1 1 1 2 2 2 1 Exosome component EXOSC1/CSL4 Aldedh PF00171.22 KEZ38700.1 - 3.8e-76 256.5 0.0 4.6e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1978 PF09321.10 KEZ38700.1 - 0.024 13.9 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) RTA1 PF04479.13 KEZ38701.1 - 3e-37 128.2 10.5 4.1e-37 127.8 10.5 1.2 1 0 0 1 1 1 1 RTA1 like protein MIG-14_Wnt-bd PF06664.12 KEZ38701.1 - 0.0025 17.1 5.5 0.0035 16.6 5.5 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF4714 PF15833.5 KEZ38701.1 - 0.28 11.1 2.8 0.58 10.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) TMEM192 PF14802.6 KEZ38701.1 - 0.65 9.0 2.8 1.8 7.6 2.8 1.7 1 1 0 1 1 1 0 TMEM192 family PMP22_Claudin PF00822.20 KEZ38701.1 - 5.8 6.8 10.4 0.17 11.7 2.9 2.2 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin family DUF3432 PF11914.8 KEZ38701.1 - 7.7 6.8 12.9 22 5.3 12.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) NAD_binding_6 PF08030.12 KEZ38703.1 - 3.8e-17 62.8 0.0 5.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KEZ38703.1 - 6.7e-16 58.5 12.6 6.7e-16 58.5 12.6 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEZ38703.1 - 1.8e-09 37.6 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain TMEM208_SND2 PF05620.11 KEZ38703.1 - 1.4 8.7 4.4 4.3 7.1 0.2 2.6 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 SNF2_N PF00176.23 KEZ38704.1 - 1.2e-74 251.2 0.1 2.6e-74 250.1 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KEZ38704.1 - 3.1e-42 143.2 2.0 3.1e-42 143.2 2.0 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KEZ38704.1 - 4.1e-35 120.9 8.7 4.1e-35 120.9 8.7 3.8 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 KEZ38704.1 - 1.2e-18 67.4 0.0 4.9e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ38704.1 - 1.3e-10 41.6 0.1 9e-10 38.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KEZ38704.1 - 4e-06 26.2 0.0 2.2e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 KEZ38704.1 - 0.00017 21.7 0.1 0.76 10.0 0.0 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain DEAD PF00270.29 KEZ38704.1 - 0.00064 19.5 0.0 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KEZ38704.1 - 0.002 17.8 0.0 0.0071 16.0 0.0 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF1086 PF06461.11 KEZ38704.1 - 0.0053 16.6 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 KEZ38704.1 - 0.1 12.6 0.2 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.15 KEZ38704.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 WD40 PF00400.32 KEZ38705.1 - 8.1e-24 83.5 4.4 1.6e-07 31.9 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ38705.1 - 3.4e-14 52.9 0.0 0.0019 18.4 0.1 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ38705.1 - 0.0027 16.4 0.1 0.0082 14.8 0.0 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 KEZ38705.1 - 0.022 13.8 0.1 0.14 11.2 0.0 1.9 1 1 0 2 2 2 0 Coatomer WD associated region WD40_like PF17005.5 KEZ38705.1 - 0.039 13.3 0.0 2.7 7.2 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain FTHFS PF01268.19 KEZ38706.1 - 2.3e-253 841.5 0.0 3.1e-253 841.0 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KEZ38706.1 - 1.7e-69 232.2 0.6 1.7e-69 232.2 0.6 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KEZ38706.1 - 6.6e-31 107.0 0.1 1.3e-30 106.1 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 KEZ38706.1 - 0.0076 15.6 0.1 0.017 14.4 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain OCD_Mu_crystall PF02423.15 KEZ38706.1 - 0.055 12.4 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sedlin_N PF04628.13 KEZ38707.1 - 3.8e-13 49.7 0.0 7e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KEZ38707.1 - 0.022 14.7 0.0 0.067 13.1 0.0 1.7 1 1 0 1 1 1 0 Sybindin-like family TRAM1 PF08390.11 KEZ38708.1 - 0.18 11.4 0.1 0.37 10.5 0.1 1.4 1 0 0 1 1 1 0 TRAM1-like protein MCM PF00493.23 KEZ38709.1 - 4.4e-102 339.9 0.7 6.1e-102 339.5 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KEZ38709.1 - 3.4e-39 133.6 0.1 7.7e-39 132.4 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KEZ38709.1 - 4.1e-35 121.3 28.8 4.1e-35 121.3 28.8 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KEZ38709.1 - 6.4e-26 90.6 0.9 2.4e-25 88.8 0.9 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEZ38709.1 - 4.1e-15 56.3 0.5 1.4e-13 51.3 0.1 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEZ38709.1 - 5.1e-08 32.5 0.0 2.3e-06 27.2 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEZ38709.1 - 3e-06 27.3 0.0 7.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEZ38709.1 - 0.0026 17.6 0.0 0.018 14.9 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEZ38709.1 - 0.0045 16.7 0.1 0.038 13.7 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 KEZ38709.1 - 0.049 13.4 0.2 0.096 12.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF3113 PF11310.8 KEZ38709.1 - 0.053 13.5 0.0 0.22 11.5 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) zf-TFIIB PF13453.6 KEZ38709.1 - 0.2 11.0 2.0 0.41 10.0 2.0 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.20 KEZ38710.1 - 4.7e-14 52.3 5.1 4.7e-14 52.3 5.1 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) AA_permease PF00324.21 KEZ38711.1 - 2.9e-105 352.6 25.9 3.4e-105 352.4 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ38711.1 - 4.7e-37 127.8 28.8 6.4e-37 127.4 28.8 1.2 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 KEZ38711.1 - 0.00045 19.2 2.2 0.0017 17.2 2.2 2.0 1 1 0 1 1 1 1 Spore germination protein LMBR1 PF04791.16 KEZ38712.1 - 0.014 14.3 2.3 0.021 13.7 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein APH PF01636.23 KEZ38712.1 - 0.32 10.9 5.8 0.7 9.8 5.8 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family MscS_porin PF12795.7 KEZ38712.1 - 6.7 6.2 21.8 2.7 7.5 6.5 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain GFO_IDH_MocA PF01408.22 KEZ38713.1 - 5.7e-18 65.9 0.1 1.2e-17 64.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEZ38713.1 - 0.00023 21.1 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 KEZ38713.1 - 0.015 15.6 0.1 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans_2 PF11951.8 KEZ38714.1 - 4.5e-13 48.8 0.0 6.6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tab2_like PF06485.11 KEZ38714.1 - 0.07 12.6 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA-binding protein Tab2/Atab2 Patatin PF01734.22 KEZ38715.1 - 1.3e-14 54.9 0.0 2.8e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase Raptor_N PF14538.6 KEZ38716.1 - 0.0078 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Sina PF03145.16 KEZ38716.1 - 0.055 13.4 1.8 0.1 12.5 1.1 1.7 1 1 0 1 1 1 0 Seven in absentia protein family zf-TRAF PF02176.18 KEZ38716.1 - 0.12 13.1 1.3 0.34 11.6 1.3 1.8 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 KEZ38716.1 - 0.19 12.1 3.8 8.7 6.8 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KEZ38716.1 - 0.58 11.2 19.3 0.2 12.6 0.7 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ38716.1 - 0.78 10.3 23.2 0.094 13.2 0.7 4.6 5 1 0 5 5 5 0 Zinc finger, C2H2 type DUF981 PF06168.11 KEZ38718.1 - 1.1e-05 25.4 6.8 0.01 15.8 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF981) FAD_binding_4 PF01565.23 KEZ38719.1 - 3.8e-29 101.2 1.4 7.3e-29 100.3 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ38719.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like GST_N_3 PF13417.6 KEZ38720.1 - 8.3e-14 51.8 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEZ38720.1 - 7.5e-13 48.6 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEZ38720.1 - 6.1e-12 45.7 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 KEZ38720.1 - 0.004 17.3 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 KEZ38720.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEZ38720.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4407 PF14362.6 KEZ38721.1 - 0.019 14.3 0.7 0.029 13.7 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Filo_VP35 PF02097.15 KEZ38721.1 - 0.063 12.3 0.7 0.13 11.3 0.7 1.5 1 0 0 1 1 1 0 Filoviridae VP35 Nucleo_P87 PF07267.11 KEZ38721.1 - 0.18 10.6 1.8 0.26 10.1 1.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ASD2 PF08687.11 KEZ38721.1 - 0.38 10.3 5.9 0.27 10.7 4.5 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 Glyco_hydro_3_C PF01915.22 KEZ38722.1 - 2.4e-64 217.1 0.0 4.3e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ38722.1 - 5.1e-43 147.7 0.0 8.4e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ38722.1 - 1.1e-24 86.3 0.7 2.7e-24 85.0 0.7 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KEZ38722.1 - 5.5e-19 68.4 0.0 9.7e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF3176 PF11374.8 KEZ38723.1 - 2.5e-31 108.1 3.6 5.5e-31 106.9 3.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Peptidase_C2 PF00648.21 KEZ38724.1 - 3.5e-63 213.4 0.5 1.1e-61 208.5 0.5 2.4 1 1 0 1 1 1 1 Calpain family cysteine protease FTA4 PF13093.6 KEZ38725.1 - 1.2e-58 198.3 0.1 1.5e-58 198.1 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DASH_Dam1 PF08653.10 KEZ38725.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 RAG1 PF12940.7 KEZ38725.1 - 0.12 10.4 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase zf-CCHC PF00098.23 KEZ38726.1 - 3.4e-45 150.2 59.5 5.8e-08 32.5 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KEZ38726.1 - 1.2e-09 37.7 39.8 0.16 11.7 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KEZ38726.1 - 1.7e-05 24.7 42.1 0.045 13.7 0.0 6.9 4 2 2 6 6 6 3 Zinc knuckle zf-CCHC_5 PF14787.6 KEZ38726.1 - 0.00016 21.3 41.7 0.0068 16.1 1.0 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KEZ38726.1 - 0.14 12.0 0.3 0.14 12.0 0.3 6.9 5 1 2 7 7 7 0 Zinc knuckle WD40 PF00400.32 KEZ38728.1 - 4.6e-40 134.9 6.3 4.4e-07 30.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ38728.1 - 1.1e-11 44.9 0.0 0.0039 17.5 0.0 4.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Retro_M PF02813.14 KEZ38728.1 - 0.03 14.7 0.2 6.3 7.2 0.0 3.3 4 1 1 5 5 5 0 Retroviral M domain Ge1_WD40 PF16529.5 KEZ38728.1 - 0.17 10.8 0.0 11 4.9 0.0 3.0 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TRAPP PF04051.16 KEZ38729.1 - 2.3e-34 118.2 0.0 2.7e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KEZ38729.1 - 0.0029 16.5 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 KEZ38730.1 - 0.014 15.3 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 LisH DUF2939 PF11159.8 KEZ38730.1 - 0.2 12.1 0.0 0.2 12.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) TFB6 PF17110.5 KEZ38731.1 - 1.5e-57 194.1 0.0 1.9e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 KEZ38731.1 - 3.8 5.5 3.9 4.7 5.2 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KEZ38731.1 - 4.5 6.5 5.5 6.2 6.0 5.5 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KEZ38731.1 - 9.4 6.7 12.0 17 5.9 12.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chitin_synth_1 PF01644.17 KEZ38733.1 - 7.8e-74 247.1 0.2 1.2e-73 246.5 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KEZ38733.1 - 2.5e-28 97.9 0.0 4.9e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KEZ38733.1 - 1.7e-22 79.8 0.1 2.7e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KEZ38733.1 - 1.7e-07 31.3 1.6 1.7e-07 31.3 1.6 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 GHMP_kinases_N PF00288.26 KEZ38734.1 - 1.8e-08 34.5 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEZ38734.1 - 0.00032 21.0 0.0 0.00087 19.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DHDPS PF00701.22 KEZ38735.1 - 2.7e-26 91.9 0.0 5.6e-26 90.9 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF1702 PF08012.11 KEZ38735.1 - 0.1 11.4 0.2 0.17 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) DUF676 PF05057.14 KEZ38736.1 - 1.9e-50 171.4 0.0 2.6e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ38736.1 - 0.00038 21.1 0.3 0.0034 18.0 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KEZ38736.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KEZ38736.1 - 0.0042 16.8 0.1 0.052 13.3 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 KEZ38736.1 - 0.084 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Band_7 PF01145.25 KEZ38737.1 - 2.1e-25 89.8 5.7 4.7e-25 88.6 5.7 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KEZ38737.1 - 0.00051 19.2 4.4 0.00071 18.7 4.4 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DUF3103 PF11301.8 KEZ38737.1 - 0.041 12.7 0.1 0.065 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) UcrQ PF02939.16 KEZ38738.1 - 2.8e-35 120.1 0.5 3.3e-35 119.8 0.5 1.1 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.26 KEZ38739.1 - 1.8e-22 78.9 1.7 9.9e-22 76.5 0.3 2.7 2 2 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2229 PF09989.9 KEZ38739.1 - 2.6 7.6 0.0 2.6 7.6 0.0 2.6 2 1 1 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) Med3 PF11593.8 KEZ38739.1 - 4.1 6.5 10.4 2.5 7.2 2.3 2.2 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal DUF1761 PF08570.10 KEZ38740.1 - 8.1e-28 97.2 2.3 9.2e-28 97.0 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.18 KEZ38741.1 - 1.9e-56 190.1 0.0 2.7e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4603 PF15376.6 KEZ38741.1 - 1.9 5.8 8.9 2.6 5.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) IF-2B PF01008.17 KEZ38742.1 - 5.3e-42 144.0 0.1 2.2e-41 142.0 0.1 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family Acetyltransf_1 PF00583.25 KEZ38743.1 - 3.2e-12 46.7 0.0 7.2e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KEZ38743.1 - 8.2e-07 28.9 0.1 1.5e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KEZ38743.1 - 1.1e-06 28.7 0.1 1.7e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ38743.1 - 5.1e-06 26.8 0.0 9.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ38743.1 - 0.0087 16.1 0.3 0.024 14.7 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 KEZ38744.1 - 5.4e-66 218.6 4.0 1.3e-22 79.5 0.2 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Peripla_BP_7 PF18610.1 KEZ38744.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain AhpC-TSA PF00578.21 KEZ38745.1 - 4.9e-25 87.8 0.0 7.2e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ38745.1 - 1e-16 60.9 0.1 1.4e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KEZ38745.1 - 0.022 14.9 0.1 0.25 11.5 0.0 2.1 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme RNA_pol_Rpc4 PF05132.14 KEZ38745.1 - 3.1 8.2 17.9 0.42 11.0 1.4 2.7 2 1 1 3 3 3 0 RNA polymerase III RPC4 adh_short_C2 PF13561.6 KEZ38747.1 - 1.6e-45 155.5 0.9 6.8e-41 140.4 0.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ38747.1 - 2.9e-43 147.6 0.6 3.5e-43 147.3 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ38747.1 - 1.3e-14 54.6 0.3 1.8e-14 54.0 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ38747.1 - 0.00075 19.0 0.2 0.0028 17.1 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEZ38747.1 - 0.11 11.8 0.1 0.25 10.6 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UCR_14kD PF02271.16 KEZ38748.1 - 5.8e-36 122.5 0.4 7.2e-36 122.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.14 KEZ38749.1 - 3e-110 367.8 0.0 3.6e-110 367.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KEZ38749.1 - 0.0058 16.5 0.3 0.19 11.5 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Recep_L_domain PF01030.24 KEZ38750.1 - 7.1e-06 26.1 0.5 0.044 13.9 0.0 4.0 2 2 0 2 2 2 2 Receptor L domain LRR_5 PF13306.6 KEZ38750.1 - 0.014 15.4 0.8 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Lactamase_B_5 PF14597.6 KEZ38750.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily G-patch PF01585.23 KEZ38751.1 - 1.8e-13 50.2 0.8 8.6e-13 48.0 0.3 2.3 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 KEZ38751.1 - 2.4e-05 24.0 0.1 4.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 KEZ38752.1 - 1.2e-88 297.6 0.0 1.4e-88 297.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ38752.1 - 5.9e-19 68.8 0.0 1.3e-18 67.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KEZ38752.1 - 0.0002 20.4 0.0 0.0011 17.9 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KEZ38752.1 - 0.038 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 RTX C-terminal domain YCII PF03795.14 KEZ38753.1 - 3.2e-10 40.3 0.0 3.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DUF2408 PF10303.9 KEZ38754.1 - 5.5e-40 137.1 0.1 6.3e-24 85.1 0.0 4.6 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) Sigma70_ner PF04546.13 KEZ38754.1 - 0.23 11.3 5.0 0.85 9.5 5.0 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.19 KEZ38754.1 - 0.29 11.8 9.5 0.59 10.7 9.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KEZ38754.1 - 0.85 10.0 6.3 1.9 9.0 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SesA PF17107.5 KEZ38754.1 - 2.2 8.5 5.5 17 5.6 0.1 3.8 4 1 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases WRNPLPNID PF15017.6 KEZ38754.1 - 2.9 8.8 10.7 15 6.6 8.8 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Ribosomal_60s PF00428.19 KEZ38755.1 - 2.5e-27 95.3 11.7 3e-27 95.0 11.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 KEZ38755.1 - 0.78 10.4 4.0 1.1 9.9 4.0 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) UBA PF00627.31 KEZ38756.1 - 7.9e-05 22.5 0.1 0.00018 21.3 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 KEZ38756.1 - 0.0059 16.8 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 UBX domain zf-C2H2_2 PF12756.7 KEZ38756.1 - 0.033 14.5 0.2 0.08 13.3 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 KEZ38756.1 - 0.13 12.7 0.3 0.13 12.7 0.3 3.1 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RskA PF10099.9 KEZ38756.1 - 1.8 8.8 10.0 0.25 11.6 4.6 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF5568 PF17724.1 KEZ38756.1 - 3.7 7.3 12.4 6.9 6.4 11.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5568) Motile_Sperm PF00635.26 KEZ38757.1 - 6.3e-24 83.9 0.1 1.3e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KEZ38757.1 - 0.034 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SlyX PF04102.12 KEZ38757.1 - 0.087 13.5 0.2 0.2 12.3 0.2 1.6 1 0 0 1 1 1 0 SlyX FA_desaturase PF00487.24 KEZ38758.1 - 6.7e-27 94.9 16.3 9.2e-27 94.5 16.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KEZ38758.1 - 1.5e-18 66.0 0.4 2.6e-18 65.2 0.4 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ICE2 PF08426.10 KEZ38760.1 - 4.7e-153 510.1 12.0 5.3e-153 509.9 12.0 1.0 1 0 0 1 1 1 1 ICE2 Peptidase_S9 PF00326.21 KEZ38761.1 - 0.11 11.9 0.0 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Mur_ligase_M PF08245.12 KEZ38762.1 - 4.8e-09 36.5 0.0 8.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain DUF218 PF02698.17 KEZ38762.1 - 7.8e-06 25.9 0.0 3.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 DUF218 domain Mur_ligase_C PF02875.21 KEZ38762.1 - 0.012 15.8 0.0 0.092 13.0 0.0 2.4 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain UPF0146 PF03686.13 KEZ38762.1 - 0.025 14.5 0.2 0.093 12.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Pkinase PF00069.25 KEZ38764.1 - 4.7e-72 242.5 0.0 1.4e-71 241.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ38764.1 - 1.5e-50 171.9 0.0 2.3e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ38764.1 - 4e-05 22.6 0.0 6.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEZ38764.1 - 0.0099 15.2 0.0 0.064 12.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEZ38764.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RTTN_N PF14726.6 KEZ38764.1 - 1.9 9.4 3.8 4.5 8.2 0.4 2.6 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning MFS_1 PF07690.16 KEZ38765.1 - 1.4e-33 116.3 35.2 1.4e-33 116.3 35.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ38765.1 - 0.00087 18.3 22.4 0.0022 16.9 3.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ38765.1 - 1.5 7.6 24.6 0.19 10.6 6.1 3.1 2 1 1 3 3 3 0 MFS_1 like family zf-C2H2 PF00096.26 KEZ38766.1 - 0.024 15.1 0.8 0.072 13.6 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type CASP_C PF08172.12 KEZ38766.1 - 0.048 13.0 0.7 0.082 12.2 0.7 1.3 1 0 0 1 1 1 0 CASP C terminal NEMO PF11577.8 KEZ38766.1 - 0.055 13.5 2.2 0.11 12.5 2.2 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Caldesmon PF02029.15 KEZ38766.1 - 0.16 10.7 4.0 0.22 10.2 4.0 1.1 1 0 0 1 1 1 0 Caldesmon NYD-SP28_assoc PF14775.6 KEZ38766.1 - 0.72 10.0 3.0 1.5 9.0 3.0 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain PikAIV_N PF18605.1 KEZ38766.1 - 1.1 8.9 5.9 0.32 10.6 2.3 2.0 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain UPF1_Zn_bind PF09416.10 KEZ38767.1 - 5.2e-71 237.5 3.0 2.7e-70 235.2 0.9 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KEZ38767.1 - 3.1e-60 203.2 0.0 5.8e-60 202.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ38767.1 - 2.3e-54 184.9 3.1 1.8e-30 106.6 0.2 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KEZ38767.1 - 2.8e-27 94.8 0.0 5.8e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KEZ38767.1 - 1.2e-14 54.5 0.4 1e-12 48.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ38767.1 - 3.5e-11 43.6 0.1 1.2e-10 41.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KEZ38767.1 - 4.9e-06 26.7 0.0 9.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KEZ38767.1 - 3.2e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 KEZ38767.1 - 0.00014 21.7 0.1 0.4 10.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 KEZ38767.1 - 0.00028 20.2 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DUF2075 PF09848.9 KEZ38767.1 - 0.00032 20.1 0.8 0.0062 15.8 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KEZ38767.1 - 0.00053 19.8 0.2 0.0013 18.6 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 KEZ38767.1 - 0.00062 19.4 0.0 0.015 14.8 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 KEZ38767.1 - 0.0024 16.9 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain PhoH PF02562.16 KEZ38767.1 - 0.028 13.9 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KEZ38767.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 KEZ38767.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KEZ38767.1 - 0.15 12.4 0.0 0.45 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain zf-UBP PF02148.19 KEZ38767.1 - 3.5 8.0 6.0 9.1 6.7 6.0 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Brix PF04427.18 KEZ38768.1 - 1.1e-30 107.2 0.1 1.3e-30 106.9 0.1 1.1 1 0 0 1 1 1 1 Brix domain TPR_1 PF00515.28 KEZ38769.1 - 1.2e-37 126.2 19.7 0.00012 21.8 0.1 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ38769.1 - 3.3e-36 120.5 17.2 0.00025 20.9 0.0 11.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ38769.1 - 2.4e-22 79.3 4.8 1.6e-06 28.7 0.2 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ38769.1 - 1.4e-21 75.9 14.7 0.0021 17.7 0.0 8.9 7 1 2 9 9 9 5 TPR repeat TPR_8 PF13181.6 KEZ38769.1 - 4.5e-21 73.2 17.2 0.12 12.7 0.0 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ38769.1 - 7.8e-17 61.3 19.2 0.00055 20.2 0.5 7.7 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ38769.1 - 4.6e-15 54.8 6.2 0.026 14.9 0.0 8.3 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ38769.1 - 3.3e-14 53.1 21.3 5.1e-05 23.7 2.3 6.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ38769.1 - 2.8e-11 43.4 4.9 0.0031 17.6 0.1 5.3 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ38769.1 - 7.2e-10 38.8 20.3 0.047 14.5 1.2 8.5 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ38769.1 - 7.1e-08 31.9 19.2 0.23 11.6 0.3 9.0 8 2 2 10 10 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ38769.1 - 1.2e-05 24.9 1.7 0.00094 18.7 0.3 3.3 1 1 2 3 3 3 2 MalT-like TPR region BTAD PF03704.17 KEZ38769.1 - 6.4e-05 23.4 3.9 2.6 8.5 0.5 4.5 3 2 1 4 4 4 2 Bacterial transcriptional activator domain TPR_20 PF14561.6 KEZ38769.1 - 0.00066 20.0 14.0 1.5 9.2 0.2 5.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ38769.1 - 0.0012 19.4 27.3 1.8 9.4 0.0 9.4 10 0 0 10 10 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KEZ38769.1 - 0.0019 17.6 1.0 45 3.6 0.0 4.9 4 0 0 4 4 4 0 SHNi-TPR TPR_4 PF07721.14 KEZ38769.1 - 0.0032 18.0 1.0 1.1 10.0 0.3 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ38769.1 - 0.0039 17.4 19.7 1.3 9.3 0.6 6.0 5 2 2 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KEZ38769.1 - 0.017 15.0 20.0 0.25 11.2 0.7 7.7 7 0 0 7 7 7 0 Tetratricopeptide repeat MtrB PF05440.12 KEZ38769.1 - 0.052 14.0 0.0 4.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B MIT PF04212.18 KEZ38769.1 - 0.21 11.7 20.9 7.1 6.8 0.0 7.4 9 0 0 9 9 8 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 KEZ38769.1 - 0.74 10.6 3.2 9.7 7.0 0.1 4.1 3 0 0 3 3 3 0 Sel1 repeat DUF5427 PF10310.9 KEZ38769.1 - 2.5 7.0 8.1 4.3 6.2 8.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) OAD_gamma PF04277.13 KEZ38769.1 - 6.4 7.4 9.1 60 4.3 6.5 3.1 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain NARP1 PF12569.8 KEZ38769.1 - 6.4 5.6 24.9 1.7 7.4 0.6 4.4 2 2 2 4 4 4 0 NMDA receptor-regulated protein 1 Glyco_hydro_47 PF01532.20 KEZ38770.1 - 2.6e-173 577.2 0.0 3.4e-173 576.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Aminotran_4 PF01063.19 KEZ38770.1 - 2.4e-16 60.3 0.0 4.3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 KEZ38771.1 - 8e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Filament PF00038.21 KEZ38771.1 - 0.00052 19.7 19.8 0.00052 19.7 19.8 4.1 1 1 2 3 3 3 1 Intermediate filament protein ABC_tran_CTD PF16326.5 KEZ38771.1 - 0.00093 19.4 46.6 0.012 15.8 6.9 6.3 2 1 3 6 6 6 3 ABC transporter C-terminal domain TSC22 PF01166.18 KEZ38771.1 - 0.0024 18.2 23.0 0.0027 18.0 0.3 5.6 5 1 1 6 6 6 2 TSC-22/dip/bun family Leu_zip PF15294.6 KEZ38771.1 - 0.0041 16.7 11.8 0.0041 16.7 11.8 3.3 1 1 2 3 3 3 1 Leucine zipper ADIP PF11559.8 KEZ38771.1 - 0.068 13.3 50.5 0.43 10.7 7.5 5.6 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 KEZ38771.1 - 0.088 12.9 37.6 0.052 13.6 1.4 4.8 1 1 2 4 4 3 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 KEZ38771.1 - 0.096 13.2 9.4 1.2 9.6 0.3 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 KEZ38771.1 - 0.11 12.9 29.5 3.4 8.1 0.3 7.1 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KEZ38771.1 - 0.19 10.6 42.2 0.1 11.4 18.5 3.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 KEZ38771.1 - 0.48 10.5 10.7 2.3 8.3 2.3 2.8 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 KEZ38771.1 - 1.5 9.1 37.7 0.21 11.9 8.7 3.9 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KEZ38771.1 - 3 7.1 40.3 0.091 12.1 10.2 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) HALZ PF02183.18 KEZ38771.1 - 3.6 7.9 21.5 0.23 11.7 1.3 4.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper ATG16 PF08614.11 KEZ38771.1 - 3.8 7.7 67.4 0.14 12.3 25.0 4.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 KEZ38771.1 - 10 5.6 46.3 1.6 8.2 22.3 3.2 1 1 3 4 4 4 0 Mechanosensitive ion channel porin domain DnaJ PF00226.31 KEZ38772.1 - 7.5e-22 77.2 0.3 1.1e-21 76.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4510 PF14971.6 KEZ38772.1 - 0.3 11.4 0.0 0.3 11.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) Porin_3 PF01459.22 KEZ38773.1 - 2.6e-64 217.3 8.5 2.9e-64 217.2 8.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.21 KEZ38774.1 - 5.3e-93 312.5 0.0 3.7e-54 184.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KEZ38774.1 - 9.8e-37 125.6 0.0 1.6e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KEZ38774.1 - 1.1e-27 96.8 0.0 2.1e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KEZ38774.1 - 9.2e-08 31.8 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KEZ38774.1 - 0.0041 16.3 0.1 0.011 14.9 0.1 1.7 1 1 0 1 1 1 1 NAD synthase UQ_con PF00179.26 KEZ38775.1 - 2.4e-49 166.6 0.0 2.7e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ38775.1 - 0.00018 21.2 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KEZ38775.1 - 0.067 13.5 1.0 0.14 12.5 1.0 1.7 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 KEZ38776.1 - 9.7e-71 238.4 9.9 9.7e-71 238.4 9.9 1.9 2 0 0 2 2 2 1 Pex19 protein family PsbU PF06514.11 KEZ38776.1 - 0.08 12.9 0.8 0.52 10.3 0.2 2.3 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) DUF445 PF04286.12 KEZ38776.1 - 0.085 12.7 2.3 0.71 9.6 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) ABC1 PF03109.16 KEZ38778.1 - 4.9e-34 117.1 0.0 7.9e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Ribosomal_L1 PF00687.21 KEZ38778.1 - 0.099 12.4 0.0 0.79 9.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L1p/L10e family Rad52_Rad22 PF04098.15 KEZ38779.1 - 1.9e-58 196.7 0.0 2.5e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein FlgT_N PF16548.5 KEZ38779.1 - 0.21 12.1 0.0 0.51 10.9 0.0 1.6 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain Gln-synt_C PF00120.24 KEZ38780.1 - 1.5e-70 237.9 0.0 2.2e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KEZ38780.1 - 1.2e-12 48.2 0.0 2.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_76 PF03663.14 KEZ38781.1 - 3e-151 504.1 8.2 3.5e-151 503.9 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEZ38781.1 - 0.012 14.8 7.6 0.55 9.3 0.3 3.2 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 ERG4_ERG24 PF01222.17 KEZ38783.1 - 7.5e-140 466.5 19.6 8.6e-140 466.3 19.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Translin PF01997.16 KEZ38784.1 - 2.6e-44 151.7 0.1 3e-44 151.5 0.1 1.0 1 0 0 1 1 1 1 Translin family TTKRSYEDQ PF10212.9 KEZ38784.1 - 0.13 11.3 1.0 0.17 10.8 0.1 1.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein ATP-synt_C PF00137.21 KEZ38785.1 - 4.4e-35 119.8 34.4 2.1e-22 79.2 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 KEZ38786.1 - 2.8e-25 87.9 0.2 3.5e-25 87.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KEZ38786.1 - 0.00013 22.1 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KEZ38786.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Syja_N PF02383.18 KEZ38787.1 - 8.3e-86 288.2 0.0 1.2e-85 287.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KEZ38787.1 - 4.4e-38 129.5 0.0 8.3e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase ApoC-I PF04691.12 KEZ38787.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Transketolase_N PF00456.21 KEZ38788.1 - 4.4e-160 532.1 0.1 5.9e-160 531.7 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KEZ38788.1 - 2.3e-44 151.2 0.0 4.1e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ38788.1 - 3e-12 46.5 0.0 8.3e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KEZ38788.1 - 0.0022 17.3 0.0 0.007 15.6 0.0 1.6 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Btz PF09405.10 KEZ38789.1 - 1.2e-27 96.7 4.8 2.7e-27 95.6 4.8 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding N_BRCA1_IG PF16158.5 KEZ38790.1 - 5.8e-35 120.1 0.0 2e-34 118.4 0.0 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KEZ38790.1 - 4.4e-17 61.6 62.6 3.6e-05 23.5 7.4 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Baculo_IE-1 PF05290.11 KEZ38790.1 - 0.0047 16.9 0.6 0.0047 16.9 0.6 2.4 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) C1_2 PF03107.16 KEZ38790.1 - 0.48 10.8 50.4 0.092 13.1 10.1 4.5 4 0 0 4 4 4 0 C1 domain COPIIcoated_ERV PF07970.12 KEZ38791.1 - 5.9e-35 121.1 0.2 1.1e-34 120.3 0.2 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KEZ38791.1 - 8.5e-25 86.9 0.0 1.4e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DnaJ_CXXCXGXG PF00684.19 KEZ38792.1 - 0.13 12.7 7.3 2.6 8.5 7.3 2.4 1 1 0 1 1 1 0 DnaJ central domain HEAT PF02985.22 KEZ38793.1 - 6.1e-09 35.4 0.1 0.11 12.8 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 KEZ38793.1 - 1.2e-05 25.4 0.1 5.3e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KEZ38793.1 - 0.00046 20.6 0.4 4.8 7.8 0.0 4.1 3 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 KEZ38793.1 - 0.00052 20.3 0.0 0.051 14.0 0.0 3.3 2 1 2 4 4 4 2 HEAT repeats Adaptin_N PF01602.20 KEZ38793.1 - 0.16 10.5 0.1 1.4 7.4 0.1 2.0 2 1 1 3 3 3 0 Adaptin N terminal region Aconitase PF00330.20 KEZ38794.1 - 1.6e-148 495.6 0.0 1.9e-148 495.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ38794.1 - 1.7e-37 128.7 0.0 2.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KEZ38794.1 - 0.073 11.8 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF521) WD40 PF00400.32 KEZ38795.1 - 3.1e-40 135.4 15.8 2e-09 37.9 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ38795.1 - 9.7e-14 51.5 0.6 0.0018 18.5 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ38795.1 - 1.9e-07 30.3 0.3 0.28 10.1 0.0 4.5 2 1 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEZ38795.1 - 2.5e-06 26.4 3.2 0.022 13.5 0.1 4.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KEZ38795.1 - 0.00032 19.7 2.3 0.00065 18.7 0.1 2.5 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain HPS3_N PF14761.6 KEZ38795.1 - 0.00084 18.9 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 KEZ38795.1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Frtz PF11768.8 KEZ38795.1 - 0.0082 14.5 0.0 0.08 11.2 0.0 2.1 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 KEZ38795.1 - 0.033 13.9 0.4 12 5.6 0.1 3.0 1 1 1 2 2 2 0 TUP1-like enhancer of split Nbas_N PF15492.6 KEZ38795.1 - 0.046 13.1 0.1 4 6.7 0.0 3.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FHA PF00498.26 KEZ38796.1 - 9.5e-09 35.5 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain BUD22 PF09073.10 KEZ38796.1 - 0.19 11.0 13.4 0.25 10.6 13.4 1.1 1 0 0 1 1 1 0 BUD22 Actin PF00022.19 KEZ38798.1 - 1.9e-127 425.2 0.0 7.8e-127 423.3 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KEZ38798.1 - 0.22 10.3 0.0 13 4.5 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein PIG-F PF06699.11 KEZ38800.1 - 6.4e-59 199.1 8.6 9.9e-59 198.5 8.6 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F MMR_HSR1_C PF08438.10 KEZ38801.1 - 3.1e-37 127.5 0.0 8.1e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KEZ38801.1 - 5.7e-21 74.7 0.0 1.5e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ38801.1 - 3.9e-09 36.2 0.3 2.2e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KEZ38801.1 - 0.0051 16.4 0.1 2.4 7.6 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KEZ38801.1 - 0.017 14.2 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KEZ38801.1 - 0.031 14.3 0.1 0.18 11.9 0.2 2.0 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KEZ38801.1 - 0.064 13.2 0.2 11 5.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KEZ38801.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 KEZ38801.1 - 0.15 12.5 0.0 0.61 10.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter SET PF00856.28 KEZ38802.1 - 4.1e-05 24.0 0.0 0.0001 22.8 0.0 1.7 2 0 0 2 2 2 1 SET domain SWM_repeat PF13753.6 KEZ38802.1 - 0.037 14.2 0.1 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Putative flagellar system-associated repeat DUF3209 PF11483.8 KEZ38802.1 - 0.097 13.1 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) Fungal_trans PF04082.18 KEZ38804.1 - 4.9e-31 107.7 0.5 7.8e-31 107.1 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Trimer_CC PF08954.11 KEZ38804.1 - 0.079 12.5 1.8 0.22 11.1 1.8 1.8 1 0 0 1 1 1 0 Trimerisation motif bZIP_1 PF00170.21 KEZ38804.1 - 0.13 12.4 0.5 0.28 11.3 0.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor Auxin_repressed PF05564.12 KEZ38804.1 - 0.96 10.2 5.7 1.4 9.6 0.2 3.2 4 0 0 4 4 4 0 Dormancy/auxin associated protein GDPD PF03009.17 KEZ38805.1 - 1.8e-33 116.4 0.0 3e-33 115.7 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KEZ38805.1 - 4.4e-06 27.0 0.7 1.5e-05 25.2 0.7 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Plus-3 PF03126.18 KEZ38806.1 - 3.3e-20 72.6 0.0 1.1e-19 70.9 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain COQ7 PF03232.13 KEZ38807.1 - 4.3e-71 238.2 0.2 5.1e-71 238.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KEZ38807.1 - 6.7e-05 23.3 0.0 0.00013 22.4 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin PLDc PF00614.22 KEZ38808.1 - 9.6e-16 57.2 0.2 1.2e-06 28.4 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KEZ38808.1 - 6.3e-12 45.5 0.0 7.7e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 KEZ38808.1 - 1.9e-08 34.3 0.0 1.3e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 PX domain HSP9_HSP12 PF04119.12 KEZ38808.1 - 0.079 13.4 0.6 0.29 11.5 0.6 1.9 1 0 0 1 1 1 0 Heat shock protein 9/12 Tubulin PF00091.25 KEZ38809.1 - 2.9e-68 230.0 0.0 4.3e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEZ38809.1 - 6.6e-45 152.3 0.3 1.2e-44 151.5 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KEZ38809.1 - 2.9e-07 30.8 0.0 6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KEZ38809.1 - 0.059 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain AbiEii PF08843.11 KEZ38810.1 - 8.8e-06 25.8 0.3 2.9e-05 24.1 0.3 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system VGLL4 PF15245.6 KEZ38811.1 - 0.058 13.5 0.4 0.058 13.5 0.4 2.4 2 1 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 TilS PF09179.11 KEZ38811.1 - 1.8 9.1 6.1 11 6.6 1.2 2.6 2 0 0 2 2 2 0 TilS substrate binding domain PRK PF00485.18 KEZ38812.1 - 2.4e-07 30.7 0.0 3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 KEZ38812.1 - 1.1e-06 28.0 0.2 2.1e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 KEZ38812.1 - 1e-05 26.1 0.0 5.1e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KEZ38812.1 - 0.0014 17.9 1.9 0.0034 16.7 0.0 2.1 2 1 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KEZ38812.1 - 0.0025 18.0 0.9 0.11 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ38812.1 - 0.0028 18.1 0.0 0.0033 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 KEZ38812.1 - 0.009 15.7 0.1 0.32 10.7 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_17 PF13207.6 KEZ38812.1 - 0.01 16.3 1.0 0.59 10.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KEZ38812.1 - 0.013 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KEZ38812.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 KEZ38812.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ38812.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEZ38812.1 - 0.041 13.0 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 KEZ38812.1 - 0.048 13.6 0.5 0.083 12.8 0.5 1.3 1 0 0 1 1 1 0 NTPase dNK PF01712.19 KEZ38812.1 - 0.054 13.3 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase APS_kinase PF01583.20 KEZ38812.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.14 KEZ38812.1 - 0.091 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Viral_helicase1 PF01443.18 KEZ38812.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KEZ38812.1 - 0.12 11.9 0.5 0.23 11.1 0.5 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KEZ38812.1 - 0.13 12.3 0.3 0.79 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 KEZ38812.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KEZ38812.1 - 0.15 12.5 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KEZ38812.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain C2 PF00168.30 KEZ38813.1 - 7.1e-17 61.6 0.0 1.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain TMEM234 PF10639.9 KEZ38814.1 - 1.3e-32 112.2 0.1 3.1e-32 111.0 0.1 1.5 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KEZ38814.1 - 9.3e-06 25.9 1.7 0.012 15.8 1.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1211 PF06736.11 KEZ38814.1 - 0.062 13.7 0.0 0.73 10.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1211) DUF2011 PF09428.10 KEZ38815.1 - 0.00042 20.5 0.1 0.11 12.8 0.0 2.2 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF2011) US22 PF02393.16 KEZ38815.1 - 0.1 12.9 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 US22 like Proteasome PF00227.26 KEZ38816.1 - 3.9e-48 163.5 0.0 5.5e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEZ38816.1 - 5e-12 45.3 0.1 5e-12 45.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Alk_phosphatase PF00245.20 KEZ38816.1 - 0.12 11.4 0.1 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Alkaline phosphatase HEAT_EZ PF13513.6 KEZ38817.1 - 1.9e-15 57.0 11.7 2e-05 25.0 0.4 8.4 8 0 0 8 8 7 3 HEAT-like repeat Adaptin_N PF01602.20 KEZ38817.1 - 8.9e-14 50.9 1.4 8.4e-05 21.3 0.0 3.6 4 0 0 4 4 4 3 Adaptin N terminal region HEAT PF02985.22 KEZ38817.1 - 2.6e-13 49.0 7.4 0.06 13.6 0.1 7.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KEZ38817.1 - 8e-13 48.6 14.8 0.0019 18.6 0.7 7.4 5 1 4 9 9 9 6 HEAT repeats Cnd1 PF12717.7 KEZ38817.1 - 1.4e-09 38.2 0.8 0.0014 18.7 0.0 4.6 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEZ38817.1 - 9.7e-09 35.7 0.1 0.0091 16.6 0.0 6.1 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KEZ38817.1 - 4.1e-08 32.7 3.9 0.0025 16.9 0.5 3.6 2 1 1 3 3 3 3 Interferon-related developmental regulator (IFRD) IBN_N PF03810.19 KEZ38817.1 - 1.3e-07 31.4 0.5 8.3e-06 25.6 0.1 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 KEZ38817.1 - 6.5e-07 29.2 2.9 0.031 14.3 0.1 6.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KEZ38817.1 - 1.3e-06 28.2 0.0 0.012 15.2 0.0 4.5 4 1 1 5 5 5 1 CLASP N terminal UME PF08064.13 KEZ38817.1 - 5e-06 26.4 0.0 0.014 15.3 0.1 4.7 3 1 0 3 3 3 1 UME (NUC010) domain ParcG PF10274.9 KEZ38817.1 - 6e-05 23.2 0.1 0.5 10.5 0.0 3.7 3 1 0 3 3 3 2 Parkin co-regulated protein DUF3385 PF11865.8 KEZ38817.1 - 8.2e-05 22.6 0.1 1.2 9.0 0.1 4.0 3 1 0 3 3 3 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 KEZ38817.1 - 0.0012 18.6 0.0 16 5.2 0.0 4.2 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 KEZ38817.1 - 0.0042 17.3 0.0 0.89 9.8 0.0 3.8 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 KEZ38817.1 - 0.014 15.4 1.4 0.89 9.5 0.0 3.7 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central MMS19_C PF12460.8 KEZ38817.1 - 0.015 14.4 1.9 10 5.1 0.0 4.0 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal Tti2 PF10521.9 KEZ38817.1 - 0.11 12.0 0.0 0.67 9.4 0.0 2.4 2 0 0 2 2 1 0 Tti2 family HEAT_PBS PF03130.16 KEZ38817.1 - 0.16 12.7 8.2 0.5 11.2 0.2 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Dopey_N PF04118.14 KEZ38817.1 - 0.41 9.7 3.5 32 3.5 0.0 4.2 4 1 1 5 5 5 0 Dopey, N-terminal V-ATPase_H_N PF03224.14 KEZ38817.1 - 0.49 9.6 2.3 16 4.6 0.2 3.6 2 1 0 3 3 3 0 V-ATPase subunit H CorA PF01544.18 KEZ38818.1 - 0.031 13.6 5.6 0.072 12.4 5.6 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PIG-Y PF15159.6 KEZ38818.1 - 2.5 9.1 6.0 5.3 8.0 6.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y L_HMGIC_fpl PF10242.9 KEZ38819.1 - 7.9e-08 32.7 1.3 1.4e-07 31.9 1.3 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Spermine_synth PF01564.17 KEZ38820.1 - 5.5e-72 241.1 0.0 8.9e-72 240.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KEZ38820.1 - 4.5e-24 84.1 0.1 7.4e-24 83.4 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KEZ38820.1 - 0.00061 20.4 0.0 0.0012 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 KEZ38820.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 KEZ38820.1 - 0.047 14.4 0.2 0.21 12.4 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.7 KEZ38820.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KEZ38820.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase G-alpha PF00503.20 KEZ38821.1 - 8.2e-113 377.1 0.8 9.6e-113 376.9 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KEZ38821.1 - 4.9e-14 52.2 0.4 1.2e-08 34.7 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEZ38821.1 - 0.0001 21.7 0.2 0.015 14.7 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KEZ38821.1 - 0.021 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KEZ38821.1 - 0.04 14.1 0.2 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KEZ38821.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KEZ38821.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pro_CA PF00484.19 KEZ38822.1 - 9.3e-46 156.0 0.1 1.1e-45 155.7 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Methyltransf_23 PF13489.6 KEZ38823.1 - 3e-17 62.9 0.0 4.4e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38823.1 - 3.8e-05 24.4 0.0 0.0033 18.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38823.1 - 0.00015 22.4 0.0 1.4 9.6 0.0 3.1 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38823.1 - 0.00098 18.9 0.0 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38823.1 - 0.0011 19.5 0.0 0.15 12.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38823.1 - 0.0021 17.4 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TFIIF_alpha PF05793.12 KEZ38824.1 - 0.17 10.4 9.0 0.32 9.5 9.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Not1 PF04054.15 KEZ38825.1 - 9.4e-114 380.1 0.0 1.9e-113 379.1 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KEZ38825.1 - 5.4e-91 304.0 2.2 1e-90 303.1 2.2 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KEZ38825.1 - 3e-49 166.7 1.4 3e-49 166.7 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KEZ38825.1 - 8e-40 136.0 0.0 2.2e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KEZ38825.1 - 2.8e-35 121.6 0.9 1.1e-34 119.7 0.1 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Seipin PF06775.14 KEZ38826.1 - 5.6e-47 160.4 0.5 8.9e-47 159.7 0.5 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.23 KEZ38826.1 - 4.1e-13 49.4 0.0 8.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KEZ38826.1 - 6.2e-10 38.5 0.1 1.3e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KEZ38826.1 - 4.8e-06 26.1 0.0 2.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KEZ38826.1 - 3e-05 23.8 0.1 7.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain NTF2 PF02136.20 KEZ38828.1 - 2.1e-29 102.5 0.5 2.4e-29 102.4 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain OKR_DC_1_C PF03711.15 KEZ38828.1 - 0.00042 20.6 0.0 0.00048 20.4 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain DUF4440 PF14534.6 KEZ38828.1 - 0.056 13.8 0.0 0.068 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ribosomal_L7Ae PF01248.26 KEZ38829.1 - 4.6e-21 74.4 0.5 4.6e-21 74.4 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KEZ38829.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 CLPTM1 PF05602.12 KEZ38829.1 - 0.039 13.0 0.2 0.047 12.7 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MOZ_SAS PF01853.18 KEZ38830.1 - 1.7e-77 259.2 0.0 2.4e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEZ38830.1 - 7.4e-21 73.5 3.4 1.5e-20 72.6 3.4 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KEZ38830.1 - 8.2e-08 32.2 8.6 2.9e-07 30.5 8.6 2.0 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KEZ38830.1 - 0.00013 21.8 7.4 0.00013 21.8 7.4 2.2 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 KEZ38830.1 - 0.025 14.8 2.7 0.25 11.5 2.9 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.22 KEZ38830.1 - 0.063 13.2 1.0 0.19 11.6 1.0 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_7 PF13508.7 KEZ38830.1 - 0.17 12.3 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-HC5HC2H PF13771.6 KEZ38830.1 - 0.23 11.7 3.4 0.61 10.4 3.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KEZ38830.1 - 0.29 10.7 2.5 0.85 9.2 2.5 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 KEZ38830.1 - 1.2 9.1 6.0 2.1 8.3 6.0 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-4CXXC_R1 PF10497.9 KEZ38830.1 - 4.2 7.7 8.4 0.32 11.2 3.3 1.8 2 0 0 2 2 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ENTH PF01417.20 KEZ38831.1 - 4.9e-49 165.5 0.1 7.9e-49 164.9 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KEZ38831.1 - 6.4e-05 23.3 21.8 6.4e-05 23.3 21.8 5.3 1 1 2 3 3 3 2 Domain of unknown function (DUF1720) ANTH PF07651.16 KEZ38831.1 - 0.00093 18.3 0.0 0.0018 17.3 0.0 1.5 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 KEZ38831.1 - 0.0031 17.3 0.6 0.0031 17.3 0.6 2.9 2 0 0 2 2 2 1 Ubiquitin interaction motif AIDA PF16168.5 KEZ38831.1 - 0.076 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk VHS PF00790.19 KEZ38831.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 VHS domain Tudor_3 PF18115.1 KEZ38833.1 - 8.6e-05 22.3 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KEZ38833.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) IL11 PF07400.11 KEZ38833.1 - 0.046 13.4 0.2 0.075 12.7 0.2 1.3 1 0 0 1 1 1 0 Interleukin 11 CCDC-167 PF15188.6 KEZ38833.1 - 0.053 13.9 1.9 0.088 13.2 1.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Nup96 PF12110.8 KEZ38834.1 - 3.4e-97 325.1 1.3 4.8e-97 324.6 1.3 1.2 1 0 0 1 1 1 1 Nuclear protein 96 ParA PF10609.9 KEZ38834.1 - 5.6e-66 222.5 6.6 2e-62 210.9 0.0 2.7 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase Nucleoporin2 PF04096.14 KEZ38834.1 - 3e-51 173.5 0.0 4.7e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KEZ38834.1 - 1.7e-08 35.2 76.0 1.3e-06 29.1 28.8 10.6 4 2 6 10 10 10 4 Nucleoporin FG repeat region AAA_31 PF13614.6 KEZ38834.1 - 0.025 14.5 3.8 0.022 14.7 1.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KEZ38834.1 - 0.063 12.7 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CbiA PF01656.23 KEZ38834.1 - 0.072 13.1 0.4 1.2 9.2 0.3 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain UCH_1 PF13423.6 KEZ38835.1 - 6e-75 252.8 3.9 4.6e-43 148.0 0.1 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KEZ38835.1 - 8.2e-23 81.7 0.0 1.4e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 KEZ38835.1 - 0.022 14.2 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.27 KEZ38837.1 - 1.4e-51 172.4 2.5 1.4e-17 63.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COX7C PF02935.16 KEZ38837.1 - 0.093 13.0 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Glyco_hydro_43 PF04616.14 KEZ38838.1 - 5.5e-65 219.5 0.3 7.1e-65 219.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KEZ38838.1 - 8.9e-25 87.6 0.0 2.9e-24 85.9 0.0 1.8 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Methyltr_RsmF_N PF17125.5 KEZ38838.1 - 0.2 12.2 0.2 18 5.9 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF VWA PF00092.28 KEZ38839.1 - 0.0032 17.7 1.1 1.1 9.5 0.0 2.6 2 1 1 3 3 3 2 von Willebrand factor type A domain VWA_2 PF13519.6 KEZ38839.1 - 0.0054 17.4 0.2 0.022 15.4 0.2 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain SPX PF03105.19 KEZ38840.1 - 1.3 8.8 5.3 1.5 8.6 5.3 1.3 1 0 0 1 1 1 0 SPX domain Methyltransf_25 PF13649.6 KEZ38841.1 - 1.8e-09 38.2 0.0 3.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38841.1 - 6.1e-08 32.6 0.0 7.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38841.1 - 5.9e-06 26.8 0.0 1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38841.1 - 6.5e-06 26.8 0.0 1.5e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ38841.1 - 0.0024 17.7 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 KEZ38841.1 - 0.005 16.0 0.0 0.0066 15.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Ubie_methyltran PF01209.18 KEZ38841.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PHY PF00360.20 KEZ38842.1 - 5e-27 94.4 0.0 1.8e-26 92.6 0.0 1.8 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.26 KEZ38842.1 - 1.1e-18 67.7 0.2 2.5e-18 66.6 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ38842.1 - 1.2e-17 64.1 0.0 2.9e-16 59.6 0.0 2.6 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KEZ38842.1 - 1.4e-12 48.4 0.0 5.7e-11 43.2 0.0 2.6 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 KEZ38842.1 - 5.4e-12 45.6 0.4 2.3e-11 43.6 0.4 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KEZ38842.1 - 1.2e-07 32.3 0.0 3.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 KEZ38842.1 - 0.012 15.5 1.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ApbA PF02558.16 KEZ38843.1 - 1.8e-32 112.1 0.0 2.4e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KEZ38843.1 - 1e-25 90.3 0.0 1.8e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.27 KEZ38843.1 - 0.071 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ38843.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Zn_clus PF00172.18 KEZ38844.1 - 1.5e-10 41.0 9.8 2.5e-10 40.3 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_N PF01213.19 KEZ38844.1 - 2.4 7.6 7.9 6.9 6.0 7.9 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TRAUB PF08164.12 KEZ38845.1 - 1.7e-27 95.7 0.1 8.4e-27 93.5 0.0 2.3 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KEZ38845.1 - 1.9e-24 86.9 0.1 1.9e-24 86.9 0.1 2.8 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Chal_sti_synt_C PF02797.15 KEZ38846.1 - 8.1e-22 77.8 0.0 1.4e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 KEZ38846.1 - 2.8e-21 76.0 0.1 4.7e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 KEZ38846.1 - 4.1e-05 23.0 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 KEZ38846.1 - 0.0037 17.4 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KEZ38846.1 - 0.047 13.5 0.3 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CAS_CSE1 PF03378.15 KEZ38846.1 - 0.19 10.1 0.0 0.32 9.4 0.0 1.3 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus adh_short PF00106.25 KEZ38847.1 - 1.4e-22 80.1 0.0 2.3e-22 79.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ38847.1 - 1.8e-17 63.7 0.0 3.8e-16 59.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ38847.1 - 1.2e-10 41.5 0.1 2.1e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 KR domain BUD22 PF09073.10 KEZ38848.1 - 4.8e-90 303.0 36.4 6.2e-90 302.6 36.4 1.1 1 0 0 1 1 1 1 BUD22 Mito_carr PF00153.27 KEZ38849.1 - 3.9e-65 215.8 2.7 1.3e-24 85.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KEZ38849.1 - 1.6 9.2 5.5 0.44 11.0 1.4 2.5 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family TLD PF07534.16 KEZ38850.1 - 0.15 12.3 0.0 6 7.1 0.0 2.2 1 1 0 1 1 1 0 TLD RCC1 PF00415.18 KEZ38851.1 - 2.9e-21 75.8 5.0 3e-06 27.8 0.1 6.6 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KEZ38851.1 - 1.1e-16 61.0 0.0 2e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KEZ38851.1 - 1.2e-07 31.3 1.2 1.2e-07 31.3 1.2 5.4 7 0 0 7 7 7 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 KEZ38851.1 - 1.3e-07 32.0 0.4 4.2e-07 30.4 0.3 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ38851.1 - 2.7e-05 24.2 0.4 0.61 10.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KEZ38851.1 - 0.00014 22.4 0.1 0.00031 21.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DDE_Tnp_1_4 PF13701.6 KEZ38851.1 - 0.031 12.5 0.0 0.056 11.7 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain group 1 DUF1389 PF07146.11 KEZ38851.1 - 0.22 10.8 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) ATG13 PF10033.9 KEZ38852.1 - 2.2e-67 227.3 0.1 3.7e-67 226.5 0.1 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 SNF2_N PF00176.23 KEZ38853.1 - 1.3e-67 228.1 1.6 1.5e-65 221.2 1.6 3.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ38853.1 - 5.7e-19 68.5 0.1 1.5e-18 67.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ38853.1 - 1.1e-06 28.7 3.0 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PEPCK_ATP PF01293.20 KEZ38854.1 - 4.1e-217 721.4 0.0 4.8e-217 721.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MRFAP1 PF15155.6 KEZ38854.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 MORF4 family-associated protein1 AAA_16 PF13191.6 KEZ38854.1 - 0.091 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KEZ38854.1 - 0.19 11.9 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KEZ38855.1 - 2.1e-42 144.9 0.0 4.2e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEZ38855.1 - 7.5e-29 100.3 0.0 2.1e-28 98.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEZ38855.1 - 1.7e-07 31.5 0.2 4e-07 30.3 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ38855.1 - 0.0018 18.3 0.1 0.01 15.9 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIA PF03153.13 KEZ38855.1 - 0.31 11.0 41.5 0.46 10.4 41.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GNAT_acetyltr_2 PF13718.6 KEZ38855.1 - 0.56 9.6 3.7 1.4 8.2 3.7 1.6 1 0 0 1 1 1 0 GNAT acetyltransferase 2 SRP-alpha_N PF04086.13 KEZ38855.1 - 8.2 6.3 20.9 17 5.2 20.9 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ran-binding PF05508.11 KEZ38856.1 - 7.2e-118 393.1 0.0 9.8e-118 392.7 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein FeoB_Cyto PF17910.1 KEZ38856.1 - 0.015 15.8 2.0 0.023 15.2 0.5 2.1 2 0 0 2 2 2 0 FeoB cytosolic helical domain VHS PF00790.19 KEZ38857.1 - 2.6e-35 121.3 0.2 5e-35 120.4 0.2 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KEZ38857.1 - 2.5e-16 59.0 0.0 5.3e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ38857.1 - 9e-15 54.3 0.1 2e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEZ38857.1 - 2.1e-13 49.7 0.1 4.2e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 KEZ38857.1 - 0.0059 16.4 4.6 0.015 15.2 4.6 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif UNC45-central PF11701.8 KEZ38857.1 - 0.092 12.7 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 KEZ38857.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) CK_II_beta PF01214.18 KEZ38858.1 - 5.3e-74 248.0 0.0 1.2e-73 246.8 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 KEZ38858.1 - 0.013 14.1 2.9 0.018 13.6 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KEZ38858.1 - 0.025 12.8 0.8 0.037 12.2 0.8 1.2 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.8 KEZ38858.1 - 0.048 14.6 8.7 0.048 14.6 8.7 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Rrp44_CSD1 PF17216.3 KEZ38858.1 - 0.12 12.1 0.4 0.66 9.7 0.2 2.0 2 0 0 2 2 2 0 Rrp44-like cold shock domain Sporozoite_P67 PF05642.11 KEZ38858.1 - 0.15 10.1 0.6 0.22 9.6 0.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PTPRCAP PF15713.5 KEZ38858.1 - 0.93 9.8 9.6 27 5.0 8.1 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PBP1_TM PF14812.6 KEZ38858.1 - 0.98 9.8 9.1 3.9 7.9 5.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 KEZ38858.1 - 1.6 6.9 7.5 2.3 6.4 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KEZ38858.1 - 2.2 7.5 7.8 2.4 7.4 6.7 1.6 2 0 0 2 2 2 0 NOA36 protein Pox_Ag35 PF03286.14 KEZ38858.1 - 3.2 7.5 8.1 0.7 9.6 4.7 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GCIP PF13324.6 KEZ38858.1 - 3.3 7.3 11.1 0.05 13.2 4.0 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF4637 PF15470.6 KEZ38858.1 - 5.6 6.7 6.9 10 5.8 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 KEZ38858.1 - 7.6 4.5 7.5 12 3.8 7.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Fungal_trans PF04082.18 KEZ38859.1 - 3.6e-12 45.9 0.1 7.9e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ38859.1 - 2.6e-07 30.7 12.1 4.4e-07 29.9 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApoO PF09769.9 KEZ38859.1 - 0.016 15.2 0.6 1.5 8.8 0.1 2.8 2 1 1 3 3 3 0 Apolipoprotein O FAA_hydrolase PF01557.18 KEZ38860.1 - 1.7e-56 191.3 0.0 2.7e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KEZ38860.1 - 9.2e-29 99.8 0.0 1.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Sulfotransfer_4 PF17784.1 KEZ38861.1 - 2.1e-53 181.3 0.0 2.6e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEZ38861.1 - 0.0002 21.8 0.3 0.0094 16.3 0.1 2.2 1 1 1 2 2 2 2 Sulfotransferase family Deltameth_res PF16020.5 KEZ38861.1 - 0.0032 17.3 0.3 0.0062 16.4 0.3 1.5 1 0 0 1 1 1 1 Deltamethrin resistance MARVEL PF01284.23 KEZ38862.1 - 3.2 7.8 16.3 0.041 13.9 3.2 2.7 1 1 0 2 2 2 0 Membrane-associating domain Glyco_hydro_16 PF00722.21 KEZ38863.1 - 6.9e-16 58.2 0.1 5e-15 55.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KEZ38863.1 - 0.0008 17.9 5.7 0.041 12.3 0.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 KEZ38863.1 - 0.046 13.3 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) IPU_b_solenoid PF18783.1 KEZ38864.1 - 0.021 14.9 0.9 0.37 10.9 0.0 2.9 3 0 0 3 3 3 0 Isopullulanase beta-solenoid repeat DUF3663 PF12404.8 KEZ38864.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.9 1 1 0 1 1 1 0 Peptidase HgmA PF04209.13 KEZ38865.1 - 2.5e-192 639.3 0.0 2.9e-192 639.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Methyltransf_23 PF13489.6 KEZ38866.1 - 2.3e-25 89.3 0.0 3.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38866.1 - 2.8e-14 53.2 0.0 3e-13 49.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38866.1 - 3.9e-14 53.1 0.0 1.1e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38866.1 - 5.4e-13 49.4 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38866.1 - 4.4e-11 43.4 0.0 1.3e-10 41.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38866.1 - 1.4e-06 27.8 0.0 9e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KEZ38866.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 KEZ38866.1 - 0.00023 21.4 0.0 0.00062 19.9 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ38866.1 - 0.00091 18.8 0.0 0.0043 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ38866.1 - 0.0016 17.7 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KEZ38866.1 - 0.0073 15.8 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KEZ38866.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KEZ38866.1 - 0.066 12.6 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 KEZ38866.1 - 0.23 10.9 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Aldolase_II PF00596.21 KEZ38867.1 - 1.8e-28 99.7 0.8 2.6e-28 99.2 0.8 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 KEZ38868.1 - 7.1e-29 100.8 24.9 2e-28 99.3 25.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily RrnaAD PF00398.20 KEZ38869.1 - 0.00021 20.5 0.0 0.00097 18.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase An_peroxidase PF03098.15 KEZ38870.1 - 1.5e-41 142.6 0.0 1.6e-29 102.9 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KEZ38870.1 - 2.2e-05 23.4 0.0 5.4e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 AA_permease PF00324.21 KEZ38871.1 - 1e-101 340.9 32.7 1.3e-101 340.6 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ38871.1 - 6.3e-27 94.5 36.2 8e-27 94.1 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3671 PF12420.8 KEZ38871.1 - 1.2 9.2 6.0 29 4.8 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function AMP-binding PF00501.28 KEZ38872.1 - 3.7e-65 220.2 0.0 1.9e-64 217.8 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ38872.1 - 4.2e-13 50.1 1.2 8.5e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glyco_hydro_61 PF03443.14 KEZ38873.1 - 2.1e-47 161.8 0.0 3.1e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Arginase PF00491.21 KEZ38874.1 - 4.9e-76 255.9 0.4 6.3e-76 255.5 0.4 1.1 1 0 0 1 1 1 1 Arginase family WW PF00397.26 KEZ38875.1 - 0.067 13.3 0.8 0.15 12.2 0.8 1.6 1 0 0 1 1 1 0 WW domain MARVEL PF01284.23 KEZ38876.1 - 2.9e-06 27.4 13.7 4e-06 26.9 13.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 KEZ38876.1 - 0.27 9.5 8.0 0.32 9.2 8.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2975 PF11188.8 KEZ38876.1 - 4.9 7.1 14.5 2.9 7.8 5.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Cnn_1N PF07989.11 KEZ38877.1 - 6.7e-22 77.4 9.7 6.7e-22 77.4 9.7 12.3 10 1 4 14 14 14 3 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KEZ38877.1 - 3.2e-08 33.7 14.6 3.2e-08 33.7 14.6 12.3 13 1 1 14 14 14 3 Micro-tubular organiser Mto1 C-term Mto2-binding region DegS PF05384.11 KEZ38877.1 - 0.00065 19.2 4.5 0.00065 19.2 4.5 7.3 4 1 3 7 7 7 1 Sensor protein DegS EzrA PF06160.12 KEZ38877.1 - 0.00083 17.7 34.1 0.00083 17.7 34.1 5.0 3 2 2 6 6 6 1 Septation ring formation regulator, EzrA DUF724 PF05266.14 KEZ38877.1 - 0.0055 16.6 13.1 0.0055 16.6 13.1 8.5 4 2 4 9 9 9 1 Protein of unknown function (DUF724) Csm1_N PF18504.1 KEZ38877.1 - 0.0097 16.2 6.1 0.0097 16.2 6.1 12.1 11 3 3 15 15 15 1 Csm1 N-terminal domain Polo_box_3 PF18544.1 KEZ38877.1 - 8.3 7.1 9.3 1.9 9.1 0.3 3.7 3 0 0 3 3 3 0 Polo box domain E1-E2_ATPase PF00122.20 KEZ38878.1 - 1e-32 113.1 9.7 1.2e-24 86.8 0.0 3.4 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEZ38878.1 - 3e-23 82.5 5.5 3e-23 82.5 5.5 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEZ38878.1 - 1.2e-19 71.4 0.0 1.1e-18 68.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ38878.1 - 2.3e-16 59.7 0.0 5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEZ38878.1 - 1.1e-13 50.7 0.1 2.7e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ38878.1 - 0.00081 19.2 0.1 0.0045 16.7 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 KEZ38878.1 - 0.2 11.6 4.0 0.6 10.1 0.8 3.0 3 0 0 3 3 3 0 CoA-binding domain Mrx7 PF10906.8 KEZ38879.1 - 0.00011 22.4 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 MIOREX complex component 7 AAA_16 PF13191.6 KEZ38880.1 - 1.2e-05 25.8 0.1 0.00052 20.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEZ38880.1 - 0.0012 19.1 0.0 0.0083 16.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KEZ38880.1 - 0.0013 18.7 0.2 0.0049 16.8 0.0 2.2 2 1 0 2 2 2 1 NACHT domain Abhydrolase_6 PF12697.7 KEZ38880.1 - 0.042 14.5 5.4 0.1 13.2 0.1 2.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family AAA_30 PF13604.6 KEZ38880.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ38880.1 - 0.15 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.12 KEZ38880.1 - 0.19 11.2 0.5 5.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein DUF676 PF05057.14 KEZ38880.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) JAB PF01398.21 KEZ38881.1 - 8.7e-14 51.5 0.0 1.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KEZ38881.1 - 3.4e-06 26.8 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 KEZ38881.1 - 0.00058 20.0 0.2 0.0011 19.2 0.2 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prefoldin_2 PF01920.20 KEZ38883.1 - 3.7e-22 78.3 12.1 4.9e-22 77.9 12.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 KEZ38883.1 - 0.00014 22.2 6.9 0.61 10.5 0.1 3.5 2 2 2 4 4 4 2 Flagella accessory protein C (FlaC) Spc24 PF08286.11 KEZ38883.1 - 0.0028 17.9 5.6 0.69 10.2 2.9 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 Prefoldin PF02996.17 KEZ38883.1 - 0.0083 16.0 14.3 0.046 13.6 2.1 3.0 1 1 2 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.6 KEZ38883.1 - 0.0091 16.0 7.7 0.029 14.4 7.7 2.0 1 1 0 1 1 1 1 Prefoldin subunit PLC-beta_C PF08703.10 KEZ38883.1 - 0.011 15.7 11.1 0.018 15.0 0.4 2.6 2 1 1 3 3 3 0 PLC-beta C terminal DUF4201 PF13870.6 KEZ38883.1 - 0.014 15.1 11.5 0.097 12.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) PHM7_cyt PF14703.6 KEZ38883.1 - 0.015 15.6 7.4 0.026 14.8 7.4 1.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MIP-T3_C PF17749.1 KEZ38883.1 - 0.026 14.5 2.0 0.026 14.5 2.0 2.3 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region PI3K_P85_iSH2 PF16454.5 KEZ38883.1 - 0.03 13.9 9.2 2.3 7.8 9.2 2.2 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HBM PF16591.5 KEZ38883.1 - 0.03 13.7 9.1 0.14 11.5 3.6 2.0 2 0 0 2 2 2 0 Helical bimodular sensor domain COG5 PF10392.9 KEZ38883.1 - 0.038 14.1 1.8 6 7.1 0.5 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FliD_C PF07195.12 KEZ38883.1 - 0.042 13.3 5.6 0.19 11.1 5.6 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus HSBP1 PF06825.12 KEZ38883.1 - 0.048 13.5 3.3 0.39 10.6 0.2 2.6 2 1 1 3 3 2 0 Heat shock factor binding protein 1 GAS PF13851.6 KEZ38883.1 - 0.064 12.6 13.4 0.079 12.3 6.2 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 KEZ38883.1 - 0.068 13.4 3.2 4.4 7.6 0.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 KEZ38883.1 - 0.071 13.6 6.2 0.75 10.3 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Bcr-Abl_Oligo PF09036.10 KEZ38883.1 - 0.091 12.8 3.8 0.092 12.8 0.1 2.3 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 KEZ38883.1 - 0.091 11.6 14.0 0.15 10.9 14.0 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein End3 PF12761.7 KEZ38883.1 - 0.096 12.9 10.4 0.12 12.5 10.4 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF4407 PF14362.6 KEZ38883.1 - 0.099 12.0 11.7 0.11 11.8 0.9 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 KEZ38883.1 - 0.11 13.3 5.1 0.37 11.6 2.3 2.1 2 0 0 2 2 2 0 Occludin homology domain Tropomyosin_1 PF12718.7 KEZ38883.1 - 0.13 12.4 14.4 0.44 10.7 6.8 2.1 2 0 0 2 2 2 0 Tropomyosin like WEMBL PF05701.11 KEZ38883.1 - 0.16 10.6 11.6 0.32 9.6 11.6 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DivIC PF04977.15 KEZ38883.1 - 0.2 11.4 19.3 1.1 9.1 9.6 3.5 2 1 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KEZ38883.1 - 0.26 11.3 12.3 0.7 9.9 4.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V-ATPase_C PF03223.15 KEZ38883.1 - 0.27 10.6 4.7 0.33 10.3 4.7 1.0 1 0 0 1 1 1 0 V-ATPase subunit C Seadorna_VP6 PF07407.11 KEZ38883.1 - 0.27 10.1 2.4 0.33 9.9 2.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein T2SSM PF04612.12 KEZ38883.1 - 0.36 10.9 7.4 2 8.5 0.2 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Tektin PF03148.14 KEZ38883.1 - 0.4 9.4 12.3 0.73 8.5 0.8 2.1 2 0 0 2 2 2 0 Tektin family JIP_LZII PF16471.5 KEZ38883.1 - 0.44 10.8 7.4 0.29 11.3 2.8 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Uso1_p115_C PF04871.13 KEZ38883.1 - 0.47 10.8 16.1 13 6.2 16.1 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CLZ PF16526.5 KEZ38883.1 - 0.48 10.8 8.9 1.2 9.6 0.7 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sas10_Utp3 PF04000.15 KEZ38883.1 - 0.52 11.0 3.7 11 6.7 2.2 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family CENP-Q PF13094.6 KEZ38883.1 - 0.52 10.5 8.6 0.72 10.0 8.6 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.12 KEZ38883.1 - 0.54 10.3 13.6 3.2 7.8 1.2 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MtrG PF04210.13 KEZ38883.1 - 0.57 10.1 2.7 0.8 9.6 0.3 2.3 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G LPP PF04728.13 KEZ38883.1 - 0.63 10.5 10.1 3.4 8.1 3.1 2.4 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KEZ38883.1 - 0.76 9.8 7.3 4.7 7.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KEZ38883.1 - 0.77 10.3 18.9 3.6 8.1 11.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Rho_Binding PF08912.11 KEZ38883.1 - 0.78 10.6 10.2 1.4 9.8 4.9 2.3 2 0 0 2 2 2 0 Rho Binding BRE1 PF08647.11 KEZ38883.1 - 0.81 9.8 11.7 3.4 7.8 4.4 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4164 PF13747.6 KEZ38883.1 - 0.85 9.9 8.3 0.38 11.1 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) betaPIX_CC PF16523.5 KEZ38883.1 - 0.88 9.4 8.1 0.15 11.9 2.8 2.3 2 2 0 2 2 2 0 betaPIX coiled coil Rx_N PF18052.1 KEZ38883.1 - 0.88 9.9 9.7 3 8.2 2.2 2.4 2 1 0 2 2 2 0 Rx N-terminal domain SlyX PF04102.12 KEZ38883.1 - 0.88 10.2 8.8 8.9 7.0 5.0 2.5 2 0 0 2 2 2 0 SlyX Snapin_Pallidin PF14712.6 KEZ38883.1 - 0.96 9.9 9.5 5.5 7.5 4.2 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Laminin_I PF06008.14 KEZ38883.1 - 1 9.0 10.4 3.4 7.3 10.5 1.7 1 1 0 1 1 1 0 Laminin Domain I Dor1 PF04124.12 KEZ38883.1 - 1.3 7.7 5.9 2.4 6.7 5.4 1.7 1 1 1 2 2 2 0 Dor1-like family GrpE PF01025.19 KEZ38883.1 - 1.3 8.7 10.7 3.2 7.4 0.8 2.3 2 0 0 2 2 2 0 GrpE FliJ PF02050.16 KEZ38883.1 - 1.3 9.2 15.3 4 7.7 6.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-H PF05837.12 KEZ38883.1 - 1.7 9.1 12.9 1.9e+02 2.5 12.7 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Swi5 PF07061.11 KEZ38883.1 - 1.7 8.8 8.4 4.5 7.4 3.2 2.4 2 0 0 2 2 2 0 Swi5 CCDC-167 PF15188.6 KEZ38883.1 - 1.7 9.0 9.4 2 8.8 0.7 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ABC_tran_CTD PF16326.5 KEZ38883.1 - 1.8 8.8 14.1 2.5 8.4 2.1 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain PRKG1_interact PF15898.5 KEZ38883.1 - 1.9 9.4 11.7 7 7.6 6.5 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 KEZ38883.1 - 1.9 9.2 8.8 1.8 9.3 3.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Prominin PF05478.11 KEZ38883.1 - 2 6.3 4.0 2.4 6.0 4.0 1.0 1 0 0 1 1 1 0 Prominin Fungal_TACC PF12709.7 KEZ38883.1 - 2.3 8.7 11.8 7.6 7.1 0.5 3.0 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Golgin_A5 PF09787.9 KEZ38883.1 - 3 7.2 15.1 0.52 9.7 0.9 2.0 1 1 0 2 2 2 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 KEZ38883.1 - 3.7 8.2 14.4 11 6.7 0.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TraF_2 PF13729.6 KEZ38883.1 - 3.7 6.8 7.2 6.9 6.0 0.8 2.0 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein TMF_TATA_bd PF12325.8 KEZ38883.1 - 3.7 7.8 12.0 3 8.1 7.6 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 KEZ38883.1 - 3.8 7.8 20.3 70 3.8 20.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.22 KEZ38883.1 - 4.2 7.6 11.1 7.2 6.9 2.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4795 PF16043.5 KEZ38883.1 - 4.5 6.8 11.7 9.1 5.8 0.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) Macoilin PF09726.9 KEZ38883.1 - 4.7 5.6 12.6 2.8 6.4 0.3 2.0 1 1 1 2 2 2 0 Macoilin family ERM PF00769.19 KEZ38883.1 - 4.8 6.9 16.1 16 5.2 16.1 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Rootletin PF15035.6 KEZ38883.1 - 5 7.1 11.5 4.2 7.4 7.1 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 KEZ38883.1 - 5.9 7.1 11.2 1.6e+02 2.4 11.2 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF812 PF05667.11 KEZ38883.1 - 7.1 5.4 14.2 55 2.4 14.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMPIT PF07851.13 KEZ38883.1 - 9.7 5.3 8.8 26 3.9 8.8 1.7 1 1 0 1 1 1 0 TMPIT-like protein AAA PF00004.29 KEZ38884.1 - 2.1e-41 141.4 0.0 3.8e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 KEZ38884.1 - 5.5e-21 74.4 4.9 5.5e-21 74.4 4.9 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 KEZ38884.1 - 3.5e-20 71.8 0.1 1.8e-19 69.5 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KEZ38884.1 - 9e-07 28.6 0.0 2.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEZ38884.1 - 2.4e-06 28.0 0.1 0.0011 19.4 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KEZ38884.1 - 2.3e-05 24.2 0.0 5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEZ38884.1 - 0.00012 22.3 0.0 0.0072 16.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KEZ38884.1 - 0.00019 21.2 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KEZ38884.1 - 0.0002 21.7 0.2 0.062 13.6 0.1 2.7 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEZ38884.1 - 0.00024 21.1 0.0 0.00097 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KEZ38884.1 - 0.00038 20.5 0.0 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KEZ38884.1 - 0.0005 19.4 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 KEZ38884.1 - 0.00093 19.0 0.0 0.0029 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KEZ38884.1 - 0.0013 18.0 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KEZ38884.1 - 0.0014 18.8 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ38884.1 - 0.002 18.7 0.1 0.0057 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KEZ38884.1 - 0.0064 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 KEZ38884.1 - 0.0069 16.0 0.1 0.53 9.8 0.1 2.6 2 1 1 3 3 3 1 AAA domain ATPase PF06745.13 KEZ38884.1 - 0.04 13.2 0.1 9.5 5.5 0.1 2.9 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.21 KEZ38884.1 - 0.043 13.2 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 KEZ38884.1 - 0.053 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KEZ38884.1 - 0.072 13.0 0.0 0.91 9.4 0.0 2.3 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.16 KEZ38884.1 - 0.16 11.4 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 KEZ38884.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Nop PF01798.18 KEZ38885.1 - 7.3e-72 241.5 0.1 7.3e-72 241.5 0.1 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KEZ38885.1 - 4.2e-13 49.5 0.1 4.2e-13 49.5 0.1 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain MRP-S27 PF10037.9 KEZ38885.1 - 0.017 14.0 0.3 0.03 13.2 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF4168 PF13767.6 KEZ38885.1 - 2.1 9.6 10.2 8.2 7.7 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) DUF1682 PF07946.14 KEZ38885.1 - 7.2 5.7 12.0 12 5.0 12.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Glyco_hydro_18 PF00704.28 KEZ38886.1 - 9.8e-87 291.6 0.1 1.1e-86 291.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 KEZ38887.1 - 4.8e-34 115.9 1.0 7.8e-34 115.3 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 KEZ38887.1 - 1.4e-26 92.3 1.8 1.4e-26 92.3 1.8 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 KEZ38887.1 - 4.8e-16 58.3 0.7 4.8e-16 58.3 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KEZ38887.1 - 2.4e-05 24.7 0.4 0.00013 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEZ38887.1 - 0.00072 19.6 0.6 0.0016 18.5 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KEZ38887.1 - 0.0039 17.5 0.6 0.0075 16.6 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KEZ38887.1 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KEZ38887.1 - 0.013 16.0 0.7 0.018 15.6 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KEZ38887.1 - 0.019 15.0 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_S26e PF01283.19 KEZ38888.1 - 1.3e-51 173.6 6.1 1.5e-51 173.4 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KEZ38888.1 - 0.03 14.3 0.6 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF1918 PF08940.11 KEZ38888.1 - 0.044 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 KEZ38888.1 - 0.089 12.6 0.7 0.14 12.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) TAP42 PF04177.12 KEZ38888.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family SMC_N PF02463.19 KEZ38889.1 - 1.3e-70 237.3 23.6 2.8e-70 236.2 23.6 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEZ38889.1 - 2.8e-25 88.9 0.0 1e-24 87.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEZ38889.1 - 1.9e-12 47.6 0.3 5.4e-05 23.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Tektin PF03148.14 KEZ38889.1 - 0.00018 20.4 11.9 0.00018 20.4 11.9 5.6 2 2 3 5 5 5 1 Tektin family AAA_29 PF13555.6 KEZ38889.1 - 0.00064 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.7 KEZ38889.1 - 0.0024 18.0 9.0 0.0024 18.0 9.0 7.5 5 2 4 9 9 7 1 Tropomyosin like THOC7 PF05615.13 KEZ38889.1 - 0.013 15.8 2.7 0.013 15.8 2.7 7.2 4 2 2 6 6 5 0 Tho complex subunit 7 Laminin_II PF06009.12 KEZ38889.1 - 0.019 15.0 1.0 0.019 15.0 1.0 8.2 2 2 6 9 9 9 0 Laminin Domain II DivIC PF04977.15 KEZ38889.1 - 0.025 14.4 0.7 0.025 14.4 0.7 10.3 6 3 4 10 10 9 0 Septum formation initiator PBP1_TM PF14812.6 KEZ38889.1 - 0.67 10.4 9.5 0.34 11.3 1.9 3.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_tran PF00005.27 KEZ38889.1 - 0.98 9.9 0.0 0.98 9.9 0.0 6.6 4 3 0 4 4 2 0 ABC transporter AT_hook PF02178.19 KEZ38889.1 - 1.2 9.3 3.8 4.2 7.6 3.8 2.0 1 0 0 1 1 1 0 AT hook motif ELYS PF13934.6 KEZ38890.1 - 6.5e-67 225.7 1.4 7.8e-67 225.5 1.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF4360 PF14273.6 KEZ38892.1 - 2.6e-14 53.5 0.0 3.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NACHT PF05729.12 KEZ38893.1 - 5.8e-06 26.3 0.2 4.1e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ38893.1 - 1.8e-05 25.2 0.1 0.00017 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain PHD PF00628.29 KEZ38893.1 - 0.00055 19.8 4.9 0.0012 18.6 4.9 1.6 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 KEZ38893.1 - 0.0018 18.7 0.1 0.015 15.8 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KEZ38893.1 - 0.0083 16.6 0.1 0.037 14.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KEZ38893.1 - 0.013 15.8 0.0 0.042 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ38893.1 - 0.029 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ38893.1 - 0.039 13.8 0.2 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KEZ38893.1 - 0.061 13.9 0.0 0.21 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ38893.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 KEZ38893.1 - 0.32 10.2 1.4 11 5.2 0.1 2.3 1 1 1 2 2 2 0 KAP family P-loop domain CUE PF02845.16 KEZ38895.1 - 6.4e-10 38.5 0.3 1.7e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 CUE domain HWE_HK PF07536.14 KEZ38895.1 - 0.02 15.6 3.1 0.13 13.0 1.0 3.0 2 1 1 3 3 3 0 HWE histidine kinase NOA36 PF06524.12 KEZ38895.1 - 0.11 11.8 1.4 0.19 11.0 1.4 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S10 PF00338.22 KEZ38896.1 - 2.7e-26 91.6 0.6 3.3e-26 91.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Nucleoporin_FG PF13634.6 KEZ38897.1 - 2.8e-10 40.9 127.7 0.00012 22.8 13.9 7.4 2 2 1 3 3 3 1 Nucleoporin FG repeat region zf-CCCH_4 PF18044.1 KEZ38897.1 - 1.3e-07 31.3 2.6 2.5e-07 30.3 2.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 KEZ38897.1 - 5.5e-07 29.3 3.9 1e-06 28.5 3.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEZ38897.1 - 1.3e-06 28.3 6.7 2.3e-06 27.4 6.7 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 KEZ38897.1 - 0.037 14.5 3.7 0.099 13.1 3.7 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KEZ38897.1 - 0.099 12.9 0.7 0.21 11.8 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger containing family Tachystatin_B PF11478.8 KEZ38897.1 - 9.2 6.3 7.6 0.98 9.4 0.7 3.0 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B Cellulase PF00150.18 KEZ38898.1 - 7e-19 68.3 0.4 1.3e-18 67.4 0.4 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 KEZ38899.1 - 9.1e-65 219.2 0.0 1.2e-64 218.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Frag1 PF10277.9 KEZ38900.1 - 5.6e-37 127.4 5.7 5.6e-37 127.4 5.7 3.2 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KEZ38900.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Ank_2 PF12796.7 KEZ38901.1 - 2.6e-110 361.2 1.7 4.1e-25 88.2 0.0 6.2 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ38901.1 - 2.2e-90 293.5 18.3 4e-09 36.5 0.0 11.6 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.6 KEZ38901.1 - 2.3e-90 295.9 24.9 2.5e-13 50.3 0.0 10.4 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ38901.1 - 3.5e-79 251.2 9.1 2.2e-07 30.6 0.0 12.0 12 0 0 12 12 11 10 Ankyrin repeat Ank_5 PF13857.6 KEZ38901.1 - 6.2e-68 224.0 11.6 3.9e-12 46.1 0.1 8.8 4 3 5 9 9 9 8 Ankyrin repeats (many copies) U3_assoc_6 PF08640.11 KEZ38901.1 - 1.1e-18 67.0 8.5 6.8e-16 58.1 0.4 3.8 3 1 1 4 4 4 2 U3 small nucleolar RNA-associated protein 6 AAA_22 PF13401.6 KEZ38901.1 - 0.00024 21.4 0.0 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEZ38901.1 - 0.0004 20.3 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ribosomal_L5 PF00281.19 KEZ38901.1 - 0.0098 16.2 0.0 0.047 14.0 0.0 2.2 2 0 0 2 2 1 1 Ribosomal protein L5 Abhydrolase_6 PF12697.7 KEZ38901.1 - 0.04 14.5 0.4 0.34 11.5 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family SesA PF17107.5 KEZ38901.1 - 0.045 13.9 0.0 0.21 11.8 0.0 2.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Hydrolase_4 PF12146.8 KEZ38901.1 - 0.079 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NRDE-2 PF08424.10 KEZ38901.1 - 4.9 6.2 7.1 0.4 9.8 2.0 1.7 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Img2 PF05046.14 KEZ38902.1 - 9.8e-26 89.9 0.0 1.3e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 KEZ38903.1 - 1.9e-39 135.2 1.7 5.7e-39 133.6 1.7 1.9 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KEZ38903.1 - 8.5e-12 45.5 0.0 2.7e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 KEZ38903.1 - 0.0012 18.5 0.1 0.0027 17.4 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 AAA_22 PF13401.6 KEZ38903.1 - 0.017 15.4 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain UspB PF10625.9 KEZ38903.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Universal stress protein B (UspB) GDI PF00996.18 KEZ38903.1 - 0.078 11.5 0.0 0.14 10.6 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF4252 PF14060.6 KEZ38903.1 - 0.1 12.5 0.3 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) ANAPC1 PF12859.7 KEZ38904.1 - 7.2e-42 143.0 4.1 2e-41 141.6 0.8 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KEZ38904.1 - 1.7e-05 25.0 2.0 0.032 14.7 0.0 4.6 4 0 0 4 4 4 1 Proteasome/cyclosome repeat Clathrin PF00637.20 KEZ38905.1 - 6.2e-20 71.5 1.9 2.8e-18 66.2 2.1 3.1 3 1 0 3 3 3 1 Region in Clathrin and VPS NBP1 PF08537.10 KEZ38905.1 - 0.0014 18.1 0.1 0.0014 18.1 0.1 1.8 2 0 0 2 2 2 1 Fungal Nap binding protein NBP1 zf-RING_5 PF14634.6 KEZ38905.1 - 0.0034 17.3 0.5 0.0062 16.5 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.9 KEZ38905.1 - 0.0036 17.6 0.6 0.013 15.8 0.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Pox_Ag35 PF03286.14 KEZ38905.1 - 0.03 14.1 11.4 0.85 9.4 9.2 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TPR_7 PF13176.6 KEZ38905.1 - 0.031 14.3 1.7 0.14 12.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 KEZ38905.1 - 0.28 9.2 20.2 0.52 8.3 20.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 KEZ38905.1 - 0.53 10.3 10.2 2 8.4 10.2 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF913 PF06025.12 KEZ38905.1 - 1.4 7.9 3.5 3.1 6.7 3.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 KEZ38905.1 - 9.6 5.3 7.2 22 4.2 7.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAD_binding_4 PF01565.23 KEZ38906.1 - 8.2e-22 77.4 0.1 2e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ38906.1 - 1.5e-14 53.8 0.9 9.6e-14 51.2 0.2 2.4 2 0 0 2 2 2 1 Berberine and berberine like Adeno_E3_CR2 PF02439.15 KEZ38908.1 - 8.7e-05 22.2 0.5 0.00015 21.4 0.5 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Syndecan PF01034.20 KEZ38908.1 - 0.007 16.3 1.1 0.012 15.5 1.1 1.3 1 0 0 1 1 1 1 Syndecan domain DUF202 PF02656.15 KEZ38908.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) SKG6 PF08693.10 KEZ38908.1 - 0.043 13.2 3.5 0.093 12.2 3.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RIFIN PF02009.16 KEZ38908.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Rifin Amnionless PF14828.6 KEZ38908.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.9 KEZ38908.1 - 0.18 10.5 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plasmodium_Vir PF05795.11 KEZ38908.1 - 0.59 9.5 1.8 1.2 8.5 1.8 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein ASFV_J13L PF05568.11 KEZ38908.1 - 1.2 8.9 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein DEAD PF00270.29 KEZ38910.1 - 9.1e-44 149.3 0.0 1.3e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ38910.1 - 9.5e-28 96.8 0.5 8.2e-27 93.7 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain API5 PF05918.11 KEZ38910.1 - 5.5e-05 22.2 4.6 7.6e-05 21.7 4.6 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) NUDIX PF00293.28 KEZ38911.1 - 6.8e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KEZ38911.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) bZIP_2 PF07716.15 KEZ38914.1 - 1.1e-05 25.4 12.6 2.7e-05 24.1 12.7 1.7 1 1 1 2 2 2 1 Basic region leucine zipper ATG16 PF08614.11 KEZ38914.1 - 0.002 18.4 3.8 0.0034 17.6 3.8 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 KEZ38914.1 - 0.0053 16.3 4.8 0.0074 15.9 4.8 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain bZIP_1 PF00170.21 KEZ38914.1 - 0.0085 16.2 9.9 0.015 15.4 9.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KEZ38914.1 - 0.0087 16.6 6.6 0.016 15.7 6.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Takusan PF04822.13 KEZ38914.1 - 0.057 13.3 4.0 0.12 12.2 4.0 1.5 1 0 0 1 1 1 0 Takusan GET2 PF08690.10 KEZ38914.1 - 1.2 8.7 4.7 1.9 8.1 4.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 NAM-associated PF14303.6 KEZ38914.1 - 7.9 7.2 11.1 0.65 10.7 5.4 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain WAP PF00095.21 KEZ38915.1 - 0.0045 17.3 3.2 0.0077 16.6 3.2 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Gamma-thionin PF00304.20 KEZ38915.1 - 0.061 13.6 4.0 0.092 13.0 4.0 1.3 1 0 0 1 1 1 0 Gamma-thionin family Ank_2 PF12796.7 KEZ38917.1 - 1.1e-47 160.5 9.6 2.2e-14 53.8 0.8 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ38917.1 - 1.1e-39 134.3 6.9 5.4e-13 49.2 0.0 6.1 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KEZ38917.1 - 2.3e-30 103.7 13.8 5.7e-05 23.4 0.2 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KEZ38917.1 - 5.2e-30 103.1 13.9 1.2e-07 31.9 0.3 7.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ38917.1 - 1.5e-29 98.7 9.4 0.00022 21.4 0.1 9.8 10 0 0 10 10 10 6 Ankyrin repeat CorA PF01544.18 KEZ38917.1 - 1.2e-09 38.0 0.7 2.6e-09 36.8 0.7 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF5305 PF17231.2 KEZ38918.1 - 0.038 13.4 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Cytochrom_B558a PF05038.13 KEZ38918.1 - 0.24 10.9 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit AA_permease_2 PF13520.6 KEZ38919.1 - 6.4e-82 275.7 29.0 7.5e-82 275.4 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ38919.1 - 9.2e-18 64.1 25.5 1.1e-17 63.8 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KEZ38919.1 - 0.0002 20.2 6.3 0.00034 19.5 6.3 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.29 KEZ38920.1 - 6.6e-08 33.1 0.0 1.9e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TraG_N PF07916.11 KEZ38922.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region HET PF06985.11 KEZ38923.1 - 4.2e-36 124.5 0.0 7.5e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.22 KEZ38924.1 - 2.1e-38 132.3 0.0 3.1e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEZ38924.1 - 2.3e-09 38.0 0.0 4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain p450 PF00067.22 KEZ38926.1 - 2.5e-53 181.5 0.0 3.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CoxIIa PF08113.11 KEZ38926.1 - 0.24 11.3 1.6 0.51 10.2 1.6 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Methyltransf_23 PF13489.6 KEZ38927.1 - 1.4e-17 64.1 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38927.1 - 2.5e-08 34.5 0.0 9.4e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38927.1 - 8.2e-07 29.7 0.0 1.7e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38927.1 - 0.00011 22.8 0.0 0.00028 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38927.1 - 0.00022 21.0 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_16 PF10294.9 KEZ38927.1 - 0.00097 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KEZ38927.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ38927.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 KEZ38927.1 - 0.035 13.9 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 KEZ38927.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldo_ket_red PF00248.21 KEZ38928.1 - 1.1e-52 179.1 0.0 3e-52 177.7 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family ScsC_N PF18312.1 KEZ38928.1 - 0.041 13.7 0.2 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain CFEM PF05730.11 KEZ38929.1 - 3.8e-09 36.5 9.5 6.6e-09 35.7 9.5 1.4 1 0 0 1 1 1 1 CFEM domain SAP130_C PF16014.5 KEZ38929.1 - 0.73 8.9 10.0 0.84 8.7 10.0 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Methyltransf_23 PF13489.6 KEZ38930.1 - 7.3e-08 32.4 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ38930.1 - 3.8e-06 27.5 0.0 7.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ38930.1 - 3.4e-05 24.5 0.0 5.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ38930.1 - 6.4e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ38930.1 - 0.001 19.7 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ38930.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ38930.1 - 0.093 12.8 0.0 1.3 9.1 0.0 2.1 1 1 0 2 2 2 0 FtsJ-like methyltransferase Peptidase_M19 PF01244.21 KEZ38931.1 - 5.4e-104 347.8 0.3 6.2e-104 347.6 0.3 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF4258 PF14076.6 KEZ38931.1 - 0.11 12.9 0.1 0.36 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) MFS_1 PF07690.16 KEZ38932.1 - 6.1e-37 127.4 53.8 3.5e-36 124.8 52.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily GST_C PF00043.25 KEZ38933.1 - 1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEZ38933.1 - 3.7e-07 30.2 0.0 6.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEZ38933.1 - 8.2e-06 26.1 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEZ38933.1 - 4.2e-05 23.8 0.0 7.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ38933.1 - 8.1e-05 22.6 0.1 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEZ38933.1 - 0.00023 21.4 0.0 0.00065 20.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.21 KEZ38934.1 - 2.8e-27 95.8 0.0 8e-27 94.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Pyr_redox_2 PF07992.14 KEZ38934.1 - 1.4e-18 67.1 0.0 2.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ38934.1 - 2.3e-10 40.3 0.0 2.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ38934.1 - 1.1e-05 24.4 0.1 0.0063 15.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KEZ38934.1 - 2.5e-05 24.0 0.7 0.00083 19.0 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ38934.1 - 4.8e-05 22.6 0.1 0.00011 21.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ38934.1 - 0.00084 19.5 0.1 0.002 18.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEZ38934.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KEZ38934.1 - 0.0031 17.5 0.4 0.55 10.2 0.1 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KEZ38934.1 - 0.0057 15.8 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEZ38934.1 - 0.023 14.0 0.0 0.064 12.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KEZ38934.1 - 0.12 11.4 0.3 0.44 9.5 0.2 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 KEZ38934.1 - 0.13 11.3 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ38934.1 - 0.16 11.3 0.1 0.29 10.4 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase BNR_2 PF13088.6 KEZ38935.1 - 0.0014 18.0 0.9 0.0059 15.9 0.9 1.8 1 1 0 1 1 1 1 BNR repeat-like domain Esterase_phd PF10503.9 KEZ38937.1 - 4.1e-23 82.0 0.3 5.7e-23 81.6 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ38937.1 - 3.7e-09 36.4 0.3 5.1e-09 35.9 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KEZ38937.1 - 0.0042 16.0 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ38937.1 - 0.0044 16.9 0.0 0.0086 15.9 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KEZ38937.1 - 0.034 13.8 0.3 0.053 13.2 0.3 1.2 1 0 0 1 1 1 0 Putative esterase Esterase PF00756.20 KEZ38938.1 - 0.00061 19.5 0.1 0.0016 18.1 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KEZ38938.1 - 0.0048 16.4 0.2 0.0076 15.8 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEZ38938.1 - 0.018 14.9 1.1 0.085 12.7 1.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KEZ38938.1 - 0.12 11.9 1.0 0.15 11.5 0.1 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase APH PF01636.23 KEZ38939.1 - 0.0014 18.7 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ38939.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Tyrosinase PF00264.20 KEZ38940.1 - 5.3e-46 157.7 0.0 7.7e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Keratin_2_head PF16208.5 KEZ38940.1 - 4 7.6 35.2 0.47 10.6 29.8 2.1 2 0 0 2 2 2 0 Keratin type II head zf-B_box PF00643.24 KEZ38941.1 - 0.002 18.2 1.9 0.002 18.2 1.9 2.5 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.6 KEZ38941.1 - 0.011 15.6 0.8 0.011 15.6 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 KEZ38941.1 - 0.04 13.9 9.0 0.4 10.7 0.3 2.9 2 0 0 2 2 2 0 Transposase zinc-binding domain Roc PF08477.13 KEZ38941.1 - 0.067 13.4 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEZ38941.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-RING_5 PF14634.6 KEZ38941.1 - 0.89 9.6 10.7 0.11 12.4 0.4 2.7 2 0 0 2 2 2 0 zinc-RING finger domain CorA PF01544.18 KEZ38942.1 - 2.9e-08 33.4 0.1 4.5e-07 29.5 0.0 2.0 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SGL PF08450.12 KEZ38943.1 - 0.00082 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Protoglobin PF11563.8 KEZ38944.1 - 4.1e-57 192.5 0.0 5e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Protoglobin MFS_1 PF07690.16 KEZ38945.1 - 1.1e-20 73.9 27.8 1.1e-20 73.9 27.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KEZ38946.1 - 1.6e-41 142.5 0.1 2.4e-41 141.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KEZ38946.1 - 7.9e-18 64.5 0.0 1.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KEZ38946.1 - 5.4e-16 58.9 3.3 4.3e-14 52.8 0.3 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KEZ38946.1 - 6.3e-16 58.2 0.0 1.6e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 KEZ38946.1 - 2.1e-13 50.0 0.7 4.6e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KEZ38946.1 - 1.8e-10 40.5 0.0 4.2e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Fer2_BFD PF04324.15 KEZ38946.1 - 9e-09 35.6 3.0 0.00013 22.2 2.5 2.7 1 1 1 2 2 2 2 BFD-like [2Fe-2S] binding domain Rubredoxin_C PF18267.1 KEZ38946.1 - 6.6e-08 32.4 0.1 0.022 14.6 0.0 3.8 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KEZ38946.1 - 0.00075 19.5 0.1 8.5 6.3 0.0 3.9 3 1 1 4 4 4 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KEZ38946.1 - 0.037 13.3 0.1 2.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KEZ38946.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mo-co_dimer PF03404.16 KEZ38947.1 - 9.6e-57 190.9 0.0 1.6e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KEZ38947.1 - 2e-52 177.3 0.0 3.7e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KEZ38947.1 - 1.7e-29 102.1 0.0 3.3e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEZ38947.1 - 1.2e-27 96.7 0.0 3.9e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KEZ38947.1 - 1.1e-17 64.0 0.0 2.2e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KEZ38947.1 - 0.0029 17.7 0.0 0.0074 16.4 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Asp PF00026.23 KEZ38948.1 - 1.1e-41 143.3 5.5 1.6e-41 142.8 5.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ38948.1 - 5.9e-09 36.4 3.8 1.9e-08 34.7 3.8 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MFS_1 PF07690.16 KEZ38949.1 - 2.6e-21 76.0 28.4 7.6e-14 51.4 8.4 3.0 2 2 2 4 4 4 3 Major Facilitator Superfamily OATP PF03137.20 KEZ38949.1 - 1.8e-05 23.3 2.2 1.8e-05 23.3 2.2 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FPN1 PF06963.12 KEZ38949.1 - 0.15 10.6 0.0 0.15 10.6 0.0 1.9 3 0 0 3 3 3 0 Ferroportin1 (FPN1) Oxidored_q6 PF01058.22 KEZ38950.1 - 2.6e-22 79.1 0.1 3.2e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Ank_2 PF12796.7 KEZ38951.1 - 1e-38 131.7 11.0 3.6e-12 46.7 0.2 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ38951.1 - 2.5e-25 87.8 9.4 2.7e-06 27.6 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KEZ38951.1 - 4.6e-24 84.5 6.4 6.3e-12 45.8 0.1 6.3 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ38951.1 - 2.9e-19 68.9 9.7 8e-07 29.2 0.1 6.9 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ38951.1 - 1.2e-18 65.2 5.2 0.0003 21.0 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat Helo_like_N PF17111.5 KEZ38951.1 - 2.8e-07 30.1 0.2 6.5e-07 28.9 0.2 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KEZ38951.1 - 0.002 18.3 0.1 0.0053 16.9 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_tran_CTD PF16326.5 KEZ38951.1 - 0.023 14.9 0.2 3.2 8.1 0.1 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain JAKMIP_CC3 PF16034.5 KEZ38951.1 - 0.043 13.8 0.2 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain VirD1 PF07328.11 KEZ38951.1 - 0.091 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 HET PF06985.11 KEZ38952.1 - 0.0013 19.1 0.2 0.63 10.4 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DA1-like PF12315.8 KEZ38953.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein DA1 DUF3325 PF11804.8 KEZ38953.1 - 0.33 11.1 9.6 0.86 9.8 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) Vma12 PF11712.8 KEZ38953.1 - 6.7 6.8 6.1 2.5 8.2 1.9 2.4 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sterol-sensing PF12349.8 KEZ38954.1 - 0.037 13.9 2.5 0.32 10.8 0.4 2.2 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation Peptidase_U4 PF03419.13 KEZ38954.1 - 3.2 7.0 7.5 5.2 6.3 7.6 1.3 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Ifi-6-16 PF06140.13 KEZ38955.1 - 3.5e-05 23.6 0.2 6e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.13 KEZ38955.1 - 0.0062 17.1 0.4 0.038 14.6 0.4 2.2 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) PfkB PF00294.24 KEZ38955.1 - 0.22 10.8 0.2 0.72 9.1 0.0 1.8 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Zn_clus PF00172.18 KEZ38956.1 - 2.3e-07 30.8 9.1 3.6e-07 30.2 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ38956.1 - 0.00013 21.1 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ38957.1 - 1.9e-27 96.2 13.8 1.9e-27 96.2 13.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5391 PF17369.2 KEZ38957.1 - 0.13 12.3 0.6 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5391) Amidohydro_2 PF04909.14 KEZ38958.1 - 1.4e-15 57.8 0.0 2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.27 KEZ38959.1 - 8.2e-27 93.0 4.1 5e-11 42.4 0.0 3.5 3 1 1 4 4 4 3 Mitochondrial carrier protein Aconitase PF00330.20 KEZ38960.1 - 7.3e-60 203.3 0.1 1.3e-59 202.4 0.1 1.4 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ38960.1 - 3.3e-41 140.7 0.0 5.4e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain RraA-like PF03737.15 KEZ38961.1 - 3.5e-35 121.4 0.0 4.3e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Sugar_tr PF00083.24 KEZ38962.1 - 9.2e-78 262.1 16.2 1.1e-77 261.8 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ38962.1 - 4.4e-16 58.7 32.2 1.1e-14 54.1 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Dabb PF07876.12 KEZ38963.1 - 1.3e-10 41.7 0.4 2.3e-10 40.9 0.4 1.4 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain CAF1A PF12253.8 KEZ38963.1 - 0.062 13.5 0.7 0.18 12.0 0.4 1.9 1 1 1 2 2 2 0 Chromatin assembly factor 1 subunit A Dak1 PF02733.17 KEZ38964.1 - 1.7e-90 303.1 0.1 2.6e-90 302.5 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KEZ38964.1 - 7.7e-43 146.4 2.8 1.1e-42 145.9 2.8 1.2 1 0 0 1 1 1 1 DAK2 domain Fungal_trans PF04082.18 KEZ38965.1 - 1.2e-18 67.1 0.0 2.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_2 PF02615.14 KEZ38966.1 - 1.9e-120 402.0 1.6 2.6e-120 401.6 1.6 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase F_bP_aldolase PF01116.20 KEZ38966.1 - 4.7e-86 288.7 0.0 3e-85 286.1 0.0 2.1 2 0 0 2 2 2 1 Fructose-bisphosphate aldolase class-II Esterase_phd PF10503.9 KEZ38968.1 - 9.5e-09 35.1 0.1 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ38968.1 - 8.9e-06 25.3 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family FMO-like PF00743.19 KEZ38969.1 - 1.3e-17 63.4 0.1 2.7e-12 45.9 0.1 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEZ38969.1 - 5.9e-10 38.8 0.0 3.4e-05 23.2 0.0 3.9 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ38969.1 - 1.1e-09 37.9 0.0 4.3e-05 22.9 0.0 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ38969.1 - 3.1e-09 36.9 0.0 8.5e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ38969.1 - 2.8e-07 30.1 0.0 9.4e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ38969.1 - 0.025 15.1 2.4 0.18 12.3 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ38969.1 - 0.053 12.6 0.1 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KEZ38969.1 - 0.082 12.1 0.9 0.24 10.6 0.0 2.1 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 KEZ38969.1 - 0.11 12.5 1.4 4.2 7.3 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 KEZ38969.1 - 0.16 11.5 0.0 24 4.3 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 KEZ38970.1 - 1.9e-22 79.6 0.5 2.9e-22 79.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KEZ38971.1 - 6.7e-45 153.0 0.6 9.1e-45 152.5 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ38971.1 - 2.5e-37 128.7 0.8 3.5e-37 128.2 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 KEZ38971.1 - 6.4e-19 68.1 17.4 6.4e-19 68.1 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily KR PF08659.10 KEZ38971.1 - 2.9e-12 46.9 0.2 4.7e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ38971.1 - 0.00079 19.0 0.1 0.0022 17.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEZ38971.1 - 0.059 12.7 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.25 KEZ38972.1 - 3.2e-39 134.4 0.0 5.1e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ38972.1 - 4.7e-30 104.9 0.0 8.1e-30 104.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ38972.1 - 2.9e-08 33.8 0.0 5.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ38972.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PglD_N PF17836.1 KEZ38972.1 - 0.013 16.2 0.2 0.43 11.3 0.1 2.4 2 0 0 2 2 2 0 PglD N-terminal domain Sacchrp_dh_NADP PF03435.18 KEZ38972.1 - 0.047 14.0 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Abhydrolase_3 PF07859.13 KEZ38973.1 - 3.3e-43 148.0 0.0 4.2e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEZ38973.1 - 0.0039 16.1 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KEZ38973.1 - 0.0083 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KEZ38973.1 - 0.054 13.0 0.0 0.098 12.1 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 KEZ38973.1 - 0.073 12.6 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2920 PF11144.8 KEZ38973.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) TauD PF02668.16 KEZ38974.1 - 4e-43 148.1 0.7 5.4e-43 147.7 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PfkB PF00294.24 KEZ38976.1 - 2.7e-20 72.9 0.6 1.2e-15 57.6 0.0 2.3 1 1 0 2 2 2 2 pfkB family carbohydrate kinase E1-E2_ATPase PF00122.20 KEZ38977.1 - 6.3e-24 84.5 12.3 4.5e-17 62.2 0.1 3.2 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 KEZ38977.1 - 4.7e-20 72.8 0.0 1.3e-16 61.5 0.0 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ38977.1 - 3.5e-17 62.3 0.0 8.6e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 KEZ38977.1 - 2.2e-16 60.1 2.8 5e-15 55.7 0.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KEZ38977.1 - 6.5e-14 51.4 0.1 2.2e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 KEZ38977.1 - 0.008 16.0 5.3 0.41 10.4 0.1 3.0 3 0 0 3 3 3 2 Predicted membrane protein (DUF2157) Hydrolase_3 PF08282.12 KEZ38977.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TraG-D_C PF12696.7 KEZ38977.1 - 0.09 12.8 0.0 1.4 8.9 0.0 2.6 1 1 1 2 2 2 0 TraM recognition site of TraD and TraG CorA PF01544.18 KEZ38978.1 - 1.1e-10 41.3 0.5 2.4e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF3169 PF11368.8 KEZ38978.1 - 0.12 11.9 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) MFS_1 PF07690.16 KEZ38979.1 - 6.6e-30 104.2 44.2 6.6e-30 104.2 44.2 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ38979.1 - 1.7e-08 33.3 9.0 3.4e-08 32.4 8.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 KEZ38980.1 - 6e-05 23.1 9.1 0.00011 22.3 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KEZ38981.1 - 8e-54 183.0 0.0 1.2e-53 182.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ38981.1 - 3.9e-33 115.0 0.0 7.4e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ38981.1 - 1.2e-06 27.9 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ38981.1 - 0.0002 21.0 0.5 0.047 13.3 0.3 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ38981.1 - 0.00095 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ38981.1 - 0.0016 18.6 0.0 0.0043 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ38981.1 - 0.0035 16.6 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEZ38981.1 - 0.02 14.2 0.0 0.062 12.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ38981.1 - 0.029 13.6 0.0 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEZ38981.1 - 0.039 14.2 0.1 0.13 12.5 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain DUF4147 PF13660.6 KEZ38981.1 - 0.094 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) NAD_binding_9 PF13454.6 KEZ38981.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Tyrosinase PF00264.20 KEZ38982.1 - 1.7e-45 156.0 1.7 1.7e-45 156.0 1.7 3.5 2 1 0 2 2 2 1 Common central domain of tyrosinase DUF3333 PF11812.8 KEZ38983.1 - 0.82 9.9 5.2 0.11 12.7 0.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3333) Tropomyosin_1 PF12718.7 KEZ38983.1 - 2.3 8.4 44.1 0.16 12.1 9.8 2.4 2 0 0 2 2 2 0 Tropomyosin like DUF2207 PF09972.9 KEZ38983.1 - 6.7 5.3 7.5 5.1 5.7 5.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CdiI_2 PF18593.1 KEZ38984.1 - 0.1 13.3 0.2 0.84 10.3 0.1 2.7 2 0 0 2 2 2 0 CdiI immunity protein CEP63 PF17045.5 KEZ38984.1 - 0.89 9.4 5.1 0.4 10.5 0.4 2.2 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF3632 PF12311.8 KEZ38985.1 - 1.2e-28 100.7 0.6 1.5e-28 100.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.20 KEZ38986.1 - 1.6e-08 35.1 0.1 2.6e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 ribonuclease Glyco_hydro_7 PF00840.20 KEZ38987.1 - 6.5e-186 618.3 15.9 7.4e-186 618.1 15.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Sulfate_transp PF00916.20 KEZ38988.1 - 2.9e-114 381.8 22.7 3.6e-114 381.4 22.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEZ38988.1 - 6.3e-10 38.7 0.0 1.9e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 KEZ38988.1 - 0.00031 21.1 3.6 0.00031 21.1 3.6 3.0 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KEZ38988.1 - 0.0016 18.7 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 STAS domain DUF1700 PF08006.11 KEZ38988.1 - 7.1 6.1 15.8 0.096 12.2 3.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) 2-Hacid_dh_C PF02826.19 KEZ38989.1 - 6.7e-44 149.4 0.0 7.8e-30 103.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEZ38989.1 - 0.0016 18.1 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 KEZ38989.1 - 0.032 13.5 0.7 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KEZ38989.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sulfotransfer_4 PF17784.1 KEZ38990.1 - 3.3e-59 200.3 0.1 4.8e-59 199.8 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEZ38990.1 - 0.00019 21.9 0.2 0.41 11.0 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Mac PF12464.8 KEZ38991.1 - 1.3 9.3 0.0 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 Maltose acetyltransferase Glyco_hydro_71 PF03659.14 KEZ38993.1 - 1.4e-127 425.6 1.9 1.8e-127 425.3 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Lipase_GDSL_2 PF13472.6 KEZ38993.1 - 1.2e-08 35.6 0.0 4.3e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ38993.1 - 0.00025 21.1 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NYN PF01936.18 KEZ38994.1 - 0.00066 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 NYN domain DUF3372 PF11852.8 KEZ38994.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) CCDC106 PF15794.5 KEZ38994.1 - 0.1 12.3 0.6 0.16 11.7 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Telomere_res PF16684.5 KEZ38994.1 - 0.18 11.3 0.1 0.37 10.2 0.0 1.4 2 0 0 2 2 2 0 Telomere resolvase DUF1648 PF07853.11 KEZ38996.1 - 0.065 12.9 0.5 0.11 12.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Cellulase PF00150.18 KEZ38997.1 - 2e-52 178.4 0.4 2.7e-52 177.9 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF924 PF06041.11 KEZ38999.1 - 4.6e-48 163.7 0.1 6.5e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DJ-1_PfpI PF01965.24 KEZ39000.1 - 2.7e-09 37.0 0.0 6.1e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family MFS_1 PF07690.16 KEZ39001.1 - 1.9e-41 142.2 53.9 2.9e-41 141.6 53.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 KEZ39002.1 - 9.7e-46 154.7 1.7 6e-45 152.1 0.9 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KEZ39002.1 - 3.4e-31 108.5 0.0 3.8e-30 105.1 0.0 2.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEZ39002.1 - 2.6e-28 98.5 4.5 5.3e-22 78.0 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Erythro-docking PF09277.11 KEZ39002.1 - 0.065 13.1 0.2 0.58 10.1 0.2 2.2 2 0 0 2 2 2 0 Erythronolide synthase, docking Lipocalin PF00061.23 KEZ39004.1 - 0.0048 17.1 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family NACHT PF05729.12 KEZ39004.1 - 0.011 15.7 0.1 0.86 9.5 0.0 2.6 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KEZ39004.1 - 0.024 14.6 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KEZ39004.1 - 0.051 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KEZ39004.1 - 0.064 13.0 0.7 0.13 12.0 0.7 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ39004.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ39004.1 - 0.16 12.4 0.1 0.87 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KEZ39004.1 - 0.16 12.0 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEZ39005.1 - 1.4e-07 31.6 0.1 2.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 KEZ39005.1 - 3.1e-07 30.0 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.6 KEZ39005.1 - 5.4e-07 30.0 1.6 9.9e-07 29.1 0.1 2.2 3 0 0 3 3 3 1 AAA domain PNP_UDP_1 PF01048.20 KEZ39005.1 - 7.3e-07 28.7 0.0 1.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.6 KEZ39005.1 - 4e-05 23.7 0.2 0.0018 18.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ39005.1 - 0.00043 20.7 0.2 0.0017 18.8 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KEZ39005.1 - 0.0059 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KEZ39005.1 - 0.026 13.8 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SAS4 PF15460.6 KEZ39005.1 - 0.028 14.5 4.2 0.69 10.0 0.3 2.5 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 AAA PF00004.29 KEZ39005.1 - 0.047 14.1 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_18 PF13512.6 KEZ39005.1 - 0.11 12.6 0.2 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HSP70 PF00012.20 KEZ39006.1 - 3.6e-05 22.2 0.1 0.051 11.8 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein TipAS PF07739.13 KEZ39007.1 - 0.18 12.4 1.2 1.3 9.6 0.5 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Laminin_I PF06008.14 KEZ39007.1 - 0.32 10.7 3.4 1.8 8.2 3.7 1.9 1 1 0 1 1 1 0 Laminin Domain I Linker_histone PF00538.19 KEZ39008.1 - 3.1e-27 94.7 0.1 6.2e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Peptidase_C39_2 PF13529.6 KEZ39008.1 - 0.098 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family SRP-alpha_N PF04086.13 KEZ39008.1 - 7.1 6.5 26.9 8.5 6.2 26.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pro_CA PF00484.19 KEZ39010.1 - 5.1e-11 43.1 1.2 5.2e-10 39.8 1.2 2.0 1 1 0 1 1 1 1 Carbonic anhydrase Glyco_hydro_115 PF15979.5 KEZ39011.1 - 2.1e-131 438.4 0.2 3e-131 437.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KEZ39011.1 - 5.3e-39 133.8 0.0 1e-38 132.9 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain ABC2_membrane PF01061.24 KEZ39012.1 - 1.2e-75 253.5 57.2 1.5e-38 132.3 24.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ39012.1 - 6.4e-37 127.1 0.0 1.2e-17 64.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEZ39012.1 - 5.3e-27 93.6 4.8 5.3e-23 80.7 0.1 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KEZ39012.1 - 6.6e-15 55.5 0.0 2.5e-14 53.6 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KEZ39012.1 - 2.5e-10 40.0 35.2 5.8e-07 28.9 15.9 3.3 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KEZ39012.1 - 6.3e-07 29.5 0.0 0.015 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ39012.1 - 1.3e-06 28.9 0.5 0.0071 16.7 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KEZ39012.1 - 1.2e-05 25.8 0.0 0.022 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEZ39012.1 - 1.5e-05 24.6 0.1 0.0086 15.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 KEZ39012.1 - 3.1e-05 24.4 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KEZ39012.1 - 3.6e-05 24.0 0.1 0.049 13.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KEZ39012.1 - 0.00017 21.3 0.1 0.0047 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEZ39012.1 - 0.0003 21.1 0.2 0.084 13.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KEZ39012.1 - 0.00033 20.6 0.1 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KEZ39012.1 - 0.0032 16.9 0.1 0.17 11.3 0.0 3.2 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KEZ39012.1 - 0.0082 16.1 0.6 4.2 7.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 KEZ39012.1 - 0.0087 15.8 0.5 3.1 7.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ39012.1 - 0.011 16.0 0.1 0.82 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEZ39012.1 - 0.017 15.5 0.0 3.8 8.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KEZ39012.1 - 0.03 14.8 0.1 0.47 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEZ39012.1 - 0.042 14.2 0.4 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KEZ39012.1 - 0.057 13.4 0.4 3.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KEZ39012.1 - 0.098 12.2 2.3 1.7 8.2 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KEZ39012.1 - 0.14 11.9 0.6 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KEZ39012.1 - 0.18 11.9 0.2 21 5.3 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Myosin_head PF00063.21 KEZ39013.1 - 5e-261 867.7 0.5 7.8e-261 867.1 0.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KEZ39013.1 - 2e-14 53.7 2.3 1e-13 51.4 0.0 3.1 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KEZ39013.1 - 9.2e-12 43.7 35.2 1.8e-05 24.1 0.6 6.9 6 0 0 6 6 6 3 IQ calmodulin-binding motif Myosin_N PF02736.19 KEZ39013.1 - 0.0002 21.1 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.12 KEZ39013.1 - 0.011 15.8 7.8 0.02 14.9 5.9 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 KEZ39013.1 - 0.019 15.3 2.9 0.021 15.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sec34 PF04136.15 KEZ39013.1 - 0.032 14.1 9.4 0.018 15.0 6.3 2.2 1 1 1 2 2 2 0 Sec34-like family AAA_16 PF13191.6 KEZ39013.1 - 0.042 14.2 0.0 0.042 14.2 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain HSF_DNA-bind PF00447.17 KEZ39013.1 - 0.067 13.8 0.3 0.31 11.7 0.3 2.2 1 0 0 1 1 1 0 HSF-type DNA-binding GAS PF13851.6 KEZ39013.1 - 0.1 11.9 31.4 0.0067 15.8 15.9 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 KEZ39013.1 - 0.98 8.2 25.4 1.7 7.5 25.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATG16 PF08614.11 KEZ39013.1 - 1.7 8.8 32.5 15 5.7 32.4 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 KEZ39013.1 - 1.8 7.8 27.6 0.92 8.8 13.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CLZ PF16526.5 KEZ39013.1 - 4.6 7.7 18.3 0.026 14.9 2.1 3.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prominin PF05478.11 KEZ39013.1 - 8.4 4.2 15.2 2.2 6.2 6.5 2.6 1 1 1 2 2 2 0 Prominin 2-Hacid_dh_C PF02826.19 KEZ39014.1 - 1.5e-52 177.5 0.0 2.7e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEZ39014.1 - 1.4e-35 121.9 0.0 2.1e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEZ39014.1 - 3.5e-05 24.0 0.6 0.00014 22.1 0.2 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KEZ39014.1 - 0.005 16.4 0.1 0.083 12.5 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KEZ39014.1 - 0.0064 16.6 0.2 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KEZ39014.1 - 0.0071 16.1 0.2 0.02 14.7 0.2 1.9 1 1 0 1 1 1 1 ACT domain XdhC_C PF13478.6 KEZ39014.1 - 0.028 14.9 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain Rossmann-like PF10727.9 KEZ39014.1 - 0.096 12.6 0.2 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 Rossmann-like domain NAP PF00956.18 KEZ39015.1 - 8.2e-100 333.4 8.5 8.2e-100 333.4 8.5 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) E1-E2_ATPase PF00122.20 KEZ39016.1 - 3.4e-29 101.7 0.0 8e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ39016.1 - 5.4e-16 59.5 0.2 3.8e-09 37.1 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KEZ39016.1 - 5.8e-08 32.9 0.0 2.3e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 P5-type ATPase cation transporter DUF2160 PF09928.9 KEZ39016.1 - 0.021 15.2 3.9 0.059 13.7 3.9 1.8 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) Cation_ATPase PF13246.6 KEZ39016.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) CMAS PF02353.20 KEZ39017.1 - 3.6e-34 118.3 0.0 5.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UQ_con PF00179.26 KEZ39017.1 - 1.3e-17 63.8 0.0 2.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Methyltransf_11 PF08241.12 KEZ39017.1 - 6.5e-17 62.0 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39017.1 - 4.9e-16 59.2 0.0 1.2e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39017.1 - 3.5e-14 52.9 0.0 5.9e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ39017.1 - 1.4e-13 51.0 0.0 2.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39017.1 - 7.4e-11 42.7 0.0 1.4e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ39017.1 - 6.5e-07 28.9 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ39017.1 - 2e-06 27.5 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ39017.1 - 2.3e-05 23.9 0.0 5.8e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 KEZ39017.1 - 0.00068 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KEZ39017.1 - 0.00094 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 KEZ39017.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltr_RsmB-F PF01189.17 KEZ39017.1 - 0.0021 17.7 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF938 PF06080.12 KEZ39017.1 - 0.0026 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 KEZ39017.1 - 0.044 12.8 0.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KEZ39017.1 - 0.062 12.6 0.0 0.41 9.9 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 KEZ39017.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.12 KEZ39017.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AA_permease PF00324.21 KEZ39018.1 - 6.9e-53 179.9 29.8 9.7e-53 179.4 29.8 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KEZ39018.1 - 4.3e-23 82.0 0.7 2.9e-08 33.2 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KEZ39018.1 - 1.4e-16 60.4 35.2 2e-16 59.9 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease SKIP_SNW PF02731.15 KEZ39019.1 - 2.3e-70 235.4 3.0 2.3e-70 235.4 3.0 2.8 3 0 0 3 3 3 1 SKIP/SNW domain EMP24_GP25L PF01105.24 KEZ39019.1 - 8e-45 153.0 1.4 1.5e-44 152.1 1.4 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD STG PF15809.5 KEZ39019.1 - 0.05 13.7 1.6 0.1 12.7 1.6 1.4 1 0 0 1 1 1 0 Simian taste bud-specific gene product family PhoD PF09423.10 KEZ39020.1 - 1.9e-40 139.0 0.0 5.2e-40 137.5 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase TauD PF02668.16 KEZ39021.1 - 4.9e-36 124.9 0.0 6e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Metallophos PF00149.28 KEZ39022.1 - 2.3e-37 129.5 0.3 4.5e-37 128.5 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase B-block_TFIIIC PF04182.12 KEZ39023.1 - 5.7e-12 45.6 0.0 3.5e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Dynamin_N PF00350.23 KEZ39025.1 - 1.5e-44 152.0 0.4 1.1e-43 149.2 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KEZ39025.1 - 4.8e-10 39.1 0.0 4.5e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KEZ39025.1 - 1.3e-05 25.3 0.0 4.8e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ39025.1 - 0.011 16.1 0.4 0.06 13.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KEZ39025.1 - 0.035 13.9 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KEZ39025.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain Cation_efflux PF01545.21 KEZ39026.1 - 1.1e-12 48.1 14.8 1.5e-12 47.7 14.8 1.1 1 0 0 1 1 1 1 Cation efflux family Ebp2 PF05890.12 KEZ39027.1 - 6.4e-93 311.2 18.5 6.4e-93 311.2 18.5 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Polysacc_syn_2C PF08485.10 KEZ39027.1 - 0.3 10.8 2.3 5.5 6.8 1.1 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal DUF2334 PF10096.9 KEZ39029.1 - 0.1 12.2 0.0 0.27 10.9 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) GATase_4 PF13230.6 KEZ39030.1 - 4.8e-17 61.8 0.0 1.2e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KEZ39030.1 - 1.1e-07 32.1 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Mito_carr PF00153.27 KEZ39031.1 - 3e-67 222.6 0.6 1.7e-24 85.5 0.0 4.2 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KEZ39031.1 - 1.8e-17 63.6 1.6 1e-07 32.3 0.3 3.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEZ39031.1 - 1.2e-16 59.2 1.1 3.2e-06 26.6 0.2 5.9 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 KEZ39031.1 - 6.7e-16 56.6 4.7 1.9e-06 27.0 0.3 5.5 6 0 0 6 6 6 3 EF hand EF-hand_5 PF13202.6 KEZ39031.1 - 4.5e-09 35.4 1.1 6.4e-05 22.3 0.4 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KEZ39031.1 - 3.6e-08 33.1 3.4 0.036 13.9 0.0 5.6 5 2 1 6 6 6 2 EF-hand domain pair EF-hand_9 PF14658.6 KEZ39031.1 - 0.0024 18.1 0.0 12 6.3 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain Dockerin_1 PF00404.18 KEZ39031.1 - 0.085 13.1 0.0 0.5 10.6 0.0 2.2 3 0 0 3 3 3 0 Dockerin type I domain Cyclin_N PF00134.23 KEZ39032.1 - 5.7e-42 142.4 0.1 9.8e-42 141.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEZ39032.1 - 1e-33 116.0 0.0 2.2e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.18 KEZ39033.1 - 0.00077 19.5 12.3 0.0014 18.7 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KEZ39033.1 - 0.0051 16.3 0.1 0.0051 16.3 0.1 2.5 3 0 0 3 3 3 1 Histone chaperone domain CHZ MFS_1 PF07690.16 KEZ39034.1 - 3.1e-32 111.9 45.1 3.1e-32 111.9 45.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ39034.1 - 0.021 13.7 15.6 0.09 11.6 5.0 3.2 1 1 0 3 3 3 0 MFS_1 like family Abhydrolase_6 PF12697.7 KEZ39035.1 - 1.9e-06 28.7 3.0 2.7e-06 28.1 3.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEZ39035.1 - 0.00021 21.2 1.0 0.0088 15.9 1.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ39035.1 - 0.0047 16.2 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ39035.1 - 0.02 14.6 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 KEZ39035.1 - 0.023 14.8 0.0 0.092 12.8 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain DUF915 PF06028.11 KEZ39035.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3089 PF11288.8 KEZ39035.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LIDHydrolase PF10230.9 KEZ39035.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 KEZ39035.1 - 0.2 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HpcH_HpaI PF03328.14 KEZ39036.1 - 0.0055 15.9 0.0 0.0062 15.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RNA_pol_Rpc4 PF05132.14 KEZ39038.1 - 1.6e-12 48.1 0.0 1.6e-12 48.1 0.0 4.1 3 2 0 3 3 3 1 RNA polymerase III RPC4 DUF1682 PF07946.14 KEZ39038.1 - 0.03 13.5 0.6 0.049 12.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) STAG PF08514.11 KEZ39039.1 - 2.8e-35 120.6 1.4 1e-34 118.8 0.7 2.4 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 KEZ39039.1 - 8.6e-05 22.9 0.1 0.37 11.2 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats SURF2 PF05477.11 KEZ39039.1 - 0.00055 19.7 1.9 0.00055 19.7 1.9 2.8 2 1 0 2 2 2 1 Surfeit locus protein 2 (SURF2) Cnd1 PF12717.7 KEZ39039.1 - 0.0017 18.4 0.2 0.49 10.4 0.1 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RsbRD_N PF14361.6 KEZ39039.1 - 0.0097 16.6 0.7 0.75 10.5 0.0 4.0 2 1 1 3 3 3 1 RsbT co-antagonist protein rsbRD N-terminal domain Caroten_synth PF04240.12 KEZ39039.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Carotenoid biosynthesis protein Baculo_PEP_C PF04513.12 KEZ39039.1 - 0.15 12.1 3.2 1.3 9.1 0.0 3.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC106 PF15794.5 KEZ39039.1 - 0.72 9.5 7.4 2.1 8.0 7.4 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 POT1PC PF16686.5 KEZ39040.1 - 7.8e-43 146.0 0.1 2.1e-42 144.6 0.0 1.8 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KEZ39040.1 - 2e-12 47.2 0.0 4.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.23 KEZ39041.1 - 4.7e-98 318.6 16.4 8.3e-14 51.1 0.2 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KEZ39041.1 - 1.1e-27 96.3 1.2 2.8e-27 95.0 1.2 1.8 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 KEZ39041.1 - 1.4e-24 86.2 8.8 2e-09 37.7 0.1 6.5 5 1 1 6 6 6 5 HEAT-like repeat Arm_3 PF16186.5 KEZ39041.1 - 3.7e-24 84.0 4.7 1.4e-23 82.1 4.2 2.2 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 KEZ39041.1 - 8.3e-20 71.0 0.3 4.6e-09 36.5 0.0 5.3 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 KEZ39041.1 - 4.9e-19 66.8 3.6 3.5e-06 26.8 0.0 7.2 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KEZ39041.1 - 3.4e-08 33.3 0.0 0.26 10.7 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 KEZ39041.1 - 2.4e-05 24.4 0.0 1.7 8.8 0.0 4.6 3 3 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 KEZ39041.1 - 4.4e-05 22.2 0.0 0.0041 15.7 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 KEZ39041.1 - 0.00045 20.3 0.0 0.92 9.5 0.0 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KEZ39041.1 - 0.00058 20.3 0.3 1.7 9.5 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 KEZ39041.1 - 0.0074 16.5 4.3 1.5 9.1 0.0 4.5 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 KEZ39041.1 - 0.013 15.1 0.0 9.7 5.7 0.0 3.8 2 2 2 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 Glycos_trans_3N PF02885.17 KEZ39041.1 - 0.029 14.2 0.0 7.2 6.5 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NAD_kinase PF01513.21 KEZ39042.1 - 1.7e-68 231.0 0.0 2.9e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase zf-C2HE PF16278.5 KEZ39043.1 - 2e-17 63.4 0.3 3.8e-17 62.5 0.3 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 KEZ39043.1 - 3.4e-16 59.8 0.6 8e-16 58.6 0.6 1.6 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEZ39043.1 - 8e-15 55.3 4.6 1.6e-13 51.1 4.6 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.25 KEZ39044.1 - 1.4e-28 100.1 0.0 1.3e-27 96.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39044.1 - 2e-11 43.7 0.0 3.9e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ39044.1 - 0.00021 20.2 0.0 0.00027 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PfkB PF00294.24 KEZ39045.1 - 3e-18 66.2 0.0 9.2e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CoA_transf_3 PF02515.17 KEZ39045.1 - 0.041 13.0 0.0 0.061 12.4 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III Las1 PF04031.13 KEZ39047.1 - 1.1e-62 210.7 0.5 1.7e-62 210.1 0.5 1.3 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 KEZ39047.1 - 1.6e-21 76.6 0.1 3.8e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KEZ39047.1 - 8.1e-14 52.1 4.6 8.1e-08 32.5 0.4 2.7 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEZ39047.1 - 0.0003 20.3 0.2 0.032 13.7 0.1 2.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase_fungal PF17667.1 KEZ39048.1 - 1.4e-69 234.9 0.0 7.1e-46 156.8 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 KEZ39048.1 - 0.0002 21.0 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KEZ39048.1 - 0.00092 18.7 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KEZ39048.1 - 0.063 13.2 0.1 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family IF4E PF01652.18 KEZ39050.1 - 6e-38 130.1 0.1 7.8e-38 129.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Helicase_C PF00271.31 KEZ39051.1 - 8.9e-17 61.4 0.0 1.8e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 KEZ39051.1 - 4.2e-16 59.2 0.1 1e-14 54.7 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEZ39051.1 - 7.7e-16 58.2 0.0 1.6e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KEZ39051.1 - 7.1e-10 38.9 0.1 1.8e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 KEZ39051.1 - 3.5e-09 36.9 0.1 7e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 RWD domain dsRBD2 PF17842.1 KEZ39051.1 - 0.0078 16.4 0.1 0.023 14.9 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 AAA_29 PF13555.6 KEZ39051.1 - 0.021 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 KEZ39051.1 - 0.021 14.2 1.1 0.031 13.6 0.0 1.7 2 0 0 2 2 2 0 KaiC DND1_DSRM PF14709.7 KEZ39051.1 - 0.028 14.7 0.2 0.085 13.1 0.2 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 KEZ39051.1 - 0.032 14.5 1.3 0.18 12.1 1.3 2.2 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEZ39051.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 KEZ39051.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEZ39051.1 - 0.47 10.9 3.0 0.35 11.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.18 KEZ39052.1 - 4.2e-08 33.2 14.2 8.2e-08 32.2 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEZ39052.1 - 0.0031 16.4 0.2 0.0044 15.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rhomboid PF01694.22 KEZ39053.1 - 1.6e-38 132.1 7.3 3.5e-38 130.9 7.3 1.6 1 0 0 1 1 1 1 Rhomboid family DNA_pol_B PF00136.21 KEZ39054.1 - 3.8e-146 487.4 1.4 5.2e-146 487.0 1.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KEZ39054.1 - 3.9e-81 272.8 0.2 9.3e-81 271.6 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KEZ39054.1 - 7.4e-18 64.8 6.0 1.5e-17 63.8 6.0 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KEZ39054.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 KEZ39054.1 - 0.01 14.7 0.2 0.038 12.8 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 KEZ39054.1 - 0.011 15.8 0.1 0.072 13.1 0.1 2.3 1 1 0 1 1 1 0 RNase_H superfamily DUF2614 PF11023.8 KEZ39054.1 - 0.079 13.1 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain GTP_EFTU PF00009.27 KEZ39055.1 - 1.1e-56 191.4 0.1 1.5e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEZ39055.1 - 2.5e-25 88.9 0.0 4.8e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEZ39055.1 - 2.1e-15 56.9 3.0 4.7e-15 55.7 3.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ39055.1 - 1.6e-05 25.0 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ39055.1 - 0.00089 19.2 0.0 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KEZ39055.1 - 0.014 15.0 0.4 0.07 12.7 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KEZ39055.1 - 0.036 13.8 0.4 18 5.1 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KEZ39055.1 - 0.071 12.5 0.1 0.26 10.6 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Grg1 PF11034.8 KEZ39056.1 - 2.8e-29 101.1 5.9 3.8e-29 100.7 5.9 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 EBP PF05241.12 KEZ39057.1 - 1.7e-67 226.4 9.8 1.9e-67 226.2 9.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF5527 PF17665.1 KEZ39058.1 - 0.062 12.8 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Romo1 PF10247.9 KEZ39058.1 - 0.075 13.4 0.6 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF2079 PF09852.9 KEZ39058.1 - 0.86 8.4 11.5 0.077 11.8 3.9 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2079) Cation_ATPase_C PF00689.21 KEZ39058.1 - 1.4 8.6 15.7 0.029 14.1 6.1 2.3 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Abhydrolase_9_N PF15420.6 KEZ39058.1 - 3.3 7.7 10.3 9.2 6.2 1.3 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus CPP1-like PF11833.8 KEZ39058.1 - 8.3 6.0 8.8 8 6.1 0.2 2.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PAP2 PF01569.21 KEZ39059.1 - 3.9e-12 46.1 7.3 1.9e-11 43.9 7.3 2.0 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 KEZ39059.1 - 0.0014 18.0 11.7 0.0014 18.0 11.7 1.7 1 1 1 2 2 2 1 UbiA prenyltransferase family DUF212 PF02681.14 KEZ39059.1 - 0.0024 18.0 0.2 0.34 11.0 0.0 2.4 2 1 0 2 2 2 2 Divergent PAP2 family DUF979 PF06166.12 KEZ39059.1 - 0.041 13.1 0.8 0.053 12.7 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF979) Transmemb_17 PF09799.9 KEZ39059.1 - 0.068 13.8 2.9 0.099 13.2 0.2 2.5 2 1 1 3 3 3 0 Predicted membrane protein IBR PF01485.21 KEZ39060.1 - 1.3e-18 67.0 38.0 3.2e-14 52.9 4.3 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 KEZ39060.1 - 2.5e-13 50.3 0.0 5.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KEZ39060.1 - 0.00024 21.3 6.3 0.00024 21.3 6.3 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KEZ39060.1 - 0.0037 17.1 6.0 0.0037 17.1 6.0 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ39060.1 - 0.0052 16.8 6.1 0.0052 16.8 6.1 3.8 3 0 0 3 3 3 1 RING-type zinc-finger NDT80_PhoG PF05224.12 KEZ39061.1 - 5.9e-35 121.2 1.7 2.1e-34 119.4 0.0 2.4 3 0 0 3 3 3 1 NDT80 / PhoG like DNA-binding family DUF3402 PF11882.8 KEZ39062.1 - 1.5e-200 667.2 0.0 2.5e-200 666.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KEZ39062.1 - 2.3e-89 299.4 0.0 4.2e-89 298.6 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein MARVEL PF01284.23 KEZ39063.1 - 0.00065 19.7 11.5 0.0082 16.2 12.9 1.9 1 1 1 2 2 2 1 Membrane-associating domain 7tm_7 PF08395.12 KEZ39063.1 - 0.27 10.4 1.5 0.51 9.5 0.2 1.8 2 0 0 2 2 2 0 7tm Chemosensory receptor Colicin_V PF02674.16 KEZ39063.1 - 3.9 7.5 8.2 2.8 7.9 4.8 2.0 2 0 0 2 2 2 0 Colicin V production protein WSC PF01822.19 KEZ39064.1 - 1.2e-41 140.8 51.7 2.2e-19 69.4 7.3 5.8 4 2 0 4 4 4 3 WSC domain peroxidase PF00141.23 KEZ39064.1 - 2.1e-20 73.4 0.0 5.1e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Peroxidase HSBP1 PF06825.12 KEZ39065.1 - 3.6e-17 62.0 0.2 4.1e-17 61.8 0.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Apolipoprotein PF01442.18 KEZ39065.1 - 0.0066 16.3 0.2 0.0076 16.1 0.2 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Matrilin_ccoil PF10393.9 KEZ39065.1 - 0.015 15.1 0.1 0.059 13.2 0.1 1.8 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CLZ PF16526.5 KEZ39065.1 - 0.031 14.6 0.1 0.044 14.1 0.1 1.3 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels WXG100 PF06013.12 KEZ39065.1 - 0.045 14.0 0.4 0.15 12.3 0.4 1.7 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 KEZ39065.1 - 0.052 13.6 0.1 0.063 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Peptidase_C50 PF03568.17 KEZ39065.1 - 0.057 12.5 0.1 0.057 12.5 0.1 1.0 1 0 0 1 1 1 0 Peptidase family C50 Seryl_tRNA_N PF02403.22 KEZ39065.1 - 0.085 13.1 1.6 0.53 10.5 1.4 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Thioredoxin PF00085.20 KEZ39066.1 - 1.3e-58 195.3 0.1 5e-30 103.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KEZ39066.1 - 2.5e-26 92.4 6.6 5.4e-26 91.3 6.6 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KEZ39066.1 - 1.3e-18 67.4 0.2 1.4e-08 35.2 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KEZ39066.1 - 4.8e-11 42.6 0.0 3.2e-05 23.4 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KEZ39066.1 - 1.6e-09 38.0 0.0 0.0019 18.5 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KEZ39066.1 - 1.4e-07 31.6 0.1 0.026 14.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KEZ39066.1 - 1.3e-06 28.4 1.0 0.025 14.5 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_6 PF13848.6 KEZ39066.1 - 4.9e-05 23.3 0.0 0.16 11.9 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Glutaredoxin PF00462.24 KEZ39066.1 - 0.00034 20.8 1.3 1.8 8.8 0.0 3.7 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin_9 PF14595.6 KEZ39066.1 - 0.00049 19.9 0.7 0.3 10.8 0.0 2.8 3 1 1 4 4 4 2 Thioredoxin TraF PF13728.6 KEZ39066.1 - 0.0013 18.6 0.9 1.3 8.8 0.0 2.7 3 0 0 3 3 3 2 F plasmid transfer operon protein Redoxin PF08534.10 KEZ39066.1 - 0.0084 15.8 0.2 0.79 9.4 0.0 2.5 2 0 0 2 2 2 1 Redoxin HyaE PF07449.11 KEZ39066.1 - 0.021 14.8 0.0 0.07 13.1 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KEZ39066.1 - 0.053 13.6 0.0 0.93 9.6 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.6 KEZ39066.1 - 0.18 12.0 6.5 14 5.8 0.1 3.8 3 1 1 4 4 4 0 Thioredoxin Bac_small_YrzI PF09501.10 KEZ39066.1 - 4.5 7.5 5.5 2.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) ELFV_dehydrog PF00208.21 KEZ39067.1 - 2.7e-83 279.4 1.3 3.4e-83 279.1 1.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KEZ39067.1 - 5.9e-50 168.5 0.0 1.4e-49 167.3 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KEZ39067.1 - 0.046 14.2 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GMC_oxred_N PF00732.19 KEZ39068.1 - 1.3e-10 41.1 0.0 6.9e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39068.1 - 1.2e-08 35.6 0.1 5.2e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Hydrolase_4 PF12146.8 KEZ39068.1 - 0.0032 16.8 0.0 0.81 8.9 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 NAD_binding_8 PF13450.6 KEZ39068.1 - 0.008 16.4 0.4 0.03 14.5 0.4 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ39068.1 - 0.047 12.9 0.1 0.13 11.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ39068.1 - 0.11 12.1 0.2 0.28 10.7 0.2 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Suc_Fer-like PF06999.12 KEZ39069.1 - 1.1e-44 152.7 0.0 1.3e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Tannase PF07519.11 KEZ39070.1 - 2.4e-84 283.9 0.0 3e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KEZ39070.1 - 0.0093 15.6 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ39070.1 - 0.033 13.7 0.0 4.1 6.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aa_trans PF01490.18 KEZ39071.1 - 3.1e-82 276.5 30.1 3.7e-82 276.2 30.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HAT_KAT11 PF08214.11 KEZ39072.1 - 2.4e-90 303.3 0.0 3.4e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein 2-Hacid_dh_C PF02826.19 KEZ39072.1 - 1.9e-35 121.8 0.0 3e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribonucleas_3_3 PF14622.6 KEZ39072.1 - 5.2e-27 94.5 0.0 9.8e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like 2-Hacid_dh PF00389.30 KEZ39072.1 - 1.9e-07 30.8 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEZ39072.1 - 1.8e-05 25.0 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ39072.1 - 0.0049 17.4 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent zf-RING_2 PF13639.6 KEZ39074.1 - 9.7e-08 32.2 6.1 1.1e-06 28.9 3.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KEZ39074.1 - 5.5e-06 26.6 7.2 1e-05 25.7 4.2 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEZ39074.1 - 0.00014 21.5 1.5 0.0053 16.5 0.1 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEZ39074.1 - 0.00015 21.5 4.9 0.00038 20.2 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ39074.1 - 0.00024 21.0 3.7 0.00048 20.0 0.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEZ39074.1 - 0.00027 20.7 2.7 0.0022 17.8 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ39074.1 - 0.0004 20.2 3.4 0.0024 17.7 1.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEZ39074.1 - 0.00044 20.2 4.5 0.036 14.1 0.1 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEZ39074.1 - 0.0005 19.9 3.1 0.0017 18.2 1.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEZ39074.1 - 0.0018 18.3 1.1 0.0018 18.3 1.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KEZ39074.1 - 0.002 17.7 1.4 0.0046 16.5 1.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 KEZ39074.1 - 0.033 14.1 2.1 0.05 13.5 0.3 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Mucin-like PF16058.5 KEZ39074.1 - 1.2 9.2 12.4 1.7 8.7 12.4 1.2 1 0 0 1 1 1 0 Mucin-like FANCL_C PF11793.8 KEZ39074.1 - 2.2 8.5 10.8 56 4.0 7.4 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 KEZ39074.1 - 3.8 7.5 7.5 0.64 10.0 3.0 2.1 2 1 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 KEZ39074.1 - 3.8 7.4 5.9 3 7.7 2.8 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KEZ39074.1 - 5.7 7.2 7.3 0.87 9.8 1.1 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING E1-E2_ATPase PF00122.20 KEZ39075.1 - 1.2e-36 126.0 18.9 2.9e-29 101.9 0.0 3.9 3 1 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEZ39075.1 - 5.4e-30 104.5 9.3 6.3e-30 104.2 4.1 2.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEZ39075.1 - 3.8e-20 73.1 0.0 3.2e-19 70.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ39075.1 - 8.3e-19 67.5 0.0 1.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEZ39075.1 - 1.3e-17 63.2 1.1 4.5e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ39075.1 - 0.00028 20.7 0.3 0.003 17.3 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 KEZ39075.1 - 2.8 7.9 7.9 0.66 10.0 1.8 2.8 3 0 0 3 3 3 0 CoA-binding domain Claudin_2 PF13903.6 KEZ39075.1 - 9.4 5.9 15.3 0.47 10.2 3.3 2.9 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction IPP-2 PF04979.14 KEZ39076.1 - 3.4e-23 82.8 5.2 3.4e-23 82.8 5.2 1.5 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF2076 PF09849.9 KEZ39077.1 - 0.075 13.1 0.1 0.075 13.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L27 PF01016.19 KEZ39078.1 - 4.9e-25 87.4 0.0 4.9e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein DUF3716 PF12511.8 KEZ39079.1 - 3.8e-05 23.7 2.5 7.9e-05 22.6 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-H2C2_2 PF13465.6 KEZ39079.1 - 0.31 11.5 5.8 0.21 12.1 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double domain LolA PF03548.15 KEZ39080.1 - 0.23 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA CorA PF01544.18 KEZ39081.1 - 2.1e-12 47.0 1.7 5.1e-12 45.7 1.7 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 KEZ39081.1 - 1.9e-06 27.6 0.0 3.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KEZ39081.1 - 0.025 13.8 0.0 0.074 12.3 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KEZ39081.1 - 0.04 13.6 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 KEZ39081.1 - 0.04 14.5 4.4 0.14 12.8 0.0 3.0 3 0 0 3 3 3 0 Alpha/beta hydrolase family LtrA PF06772.11 KEZ39081.1 - 0.054 12.7 1.2 0.085 12.1 1.2 1.2 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) PGAP1 PF07819.13 KEZ39081.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein TAFII28 PF04719.14 KEZ39082.1 - 1.9e-24 85.6 0.0 3.7e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region K_channel_TID PF07941.11 KEZ39082.1 - 6.8 7.2 7.9 1.5 9.4 2.1 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GTP_cyclohydroI PF01227.22 KEZ39083.1 - 5.9e-71 237.6 0.1 1.2e-70 236.6 0.1 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KEZ39083.1 - 0.00051 20.1 0.0 0.00099 19.2 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein Dsh_C PF12316.8 KEZ39083.1 - 0.86 10.0 6.5 1.2 9.5 6.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Dicty_REP PF05086.12 KEZ39083.1 - 6.4 4.6 10.1 8.3 4.2 10.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_76 PF03663.14 KEZ39084.1 - 1.9e-151 504.7 4.6 2.3e-151 504.5 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Porin_OmpG_1_2 PF16946.5 KEZ39084.1 - 0.024 13.9 0.2 0.041 13.2 0.2 1.3 1 0 0 1 1 1 0 OMPG-porin 1 family Glyco_hydro_88 PF07470.13 KEZ39084.1 - 0.043 12.9 7.6 0.88 8.6 0.3 3.1 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Exo_endo_phos PF03372.23 KEZ39085.1 - 1.9e-10 40.7 0.1 5e-10 39.3 0.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 KEZ39085.1 - 0.079 13.0 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region DUF4748 PF15932.5 KEZ39086.1 - 3.8e-22 77.8 0.7 5.8e-22 77.2 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) SRR1 PF07985.12 KEZ39087.1 - 2.1e-09 37.3 0.1 5.8e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 SRR1 NACHT PF05729.12 KEZ39088.1 - 1.3e-09 38.2 0.1 2.8e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ39088.1 - 0.00042 20.6 0.0 0.0032 17.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain Ish1 PF10281.9 KEZ39088.1 - 0.02 15.2 0.0 0.065 13.6 0.0 2.0 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein ABC_tran PF00005.27 KEZ39088.1 - 0.021 15.3 0.5 0.088 13.3 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_30 PF13604.6 KEZ39088.1 - 0.023 14.4 0.2 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ39088.1 - 0.034 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynactin PF12455.8 KEZ39088.1 - 0.058 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Dynein associated protein ATPase_2 PF01637.18 KEZ39088.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KEZ39088.1 - 0.14 12.7 0.9 0.92 10.1 0.0 2.9 4 0 0 4 4 4 0 AAA domain GP52 PF17468.2 KEZ39088.1 - 0.2 11.8 0.3 0.71 10.1 0.0 2.0 2 0 0 2 2 2 0 Phage gene product 52 DUF3818 PF12825.7 KEZ39089.1 - 4.3e-48 164.1 0.0 2e-30 106.0 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KEZ39089.1 - 3.5e-42 143.5 0.0 6.4e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 PX-associated Phage_RpbA PF10789.9 KEZ39089.1 - 0.074 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA M16C_assoc PF08367.11 KEZ39090.1 - 1.8e-83 279.6 0.0 2.9e-83 278.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KEZ39090.1 - 6.4e-30 104.5 0.0 3.6e-20 72.7 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEZ39090.1 - 9.3e-08 32.2 0.0 5.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 KEZ39090.1 - 0.12 12.5 0.1 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 UvrA interaction domain Taxilin PF09728.9 KEZ39091.1 - 1.6e-84 283.7 42.5 1.6e-84 283.7 42.5 1.5 2 0 0 2 2 2 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 KEZ39091.1 - 0.015 15.5 41.9 0.071 13.3 6.4 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KEZ39091.1 - 0.018 15.1 5.2 0.018 15.1 5.2 5.2 3 1 2 5 5 5 0 BRE1 E3 ubiquitin ligase DUF4810 PF16068.5 KEZ39091.1 - 0.041 14.4 0.2 0.041 14.4 0.2 3.9 5 2 1 6 6 6 0 Domain of unknown function (DUF4810) T2SSF PF00482.23 KEZ39091.1 - 0.17 11.8 1.7 0.59 10.1 1.7 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Laminin_I PF06008.14 KEZ39091.1 - 0.28 10.8 30.9 0.76 9.4 7.5 3.7 2 2 2 4 4 4 0 Laminin Domain I MAD PF05557.13 KEZ39091.1 - 0.31 9.4 45.5 0.59 8.4 19.4 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein Sec20 PF03908.13 KEZ39091.1 - 3.7 7.5 11.0 1.7 8.6 0.4 3.8 3 1 1 4 4 4 0 Sec20 Laminin_II PF06009.12 KEZ39091.1 - 6 6.9 28.5 0.27 11.3 4.7 3.9 2 2 2 4 4 4 0 Laminin Domain II Orn_Arg_deC_N PF02784.16 KEZ39092.1 - 2.9e-82 275.8 0.0 4e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KEZ39092.1 - 3.2e-19 69.0 0.0 4.3e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain WD40 PF00400.32 KEZ39093.1 - 2.3e-92 300.4 51.3 3.6e-10 40.3 0.2 12.8 12 0 0 12 12 12 12 WD domain, G-beta repeat NACHT_N PF17100.5 KEZ39093.1 - 1.1e-71 241.2 2.7 1.9e-71 240.4 2.7 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase ANAPC4_WD40 PF12894.7 KEZ39093.1 - 2.2e-26 92.0 16.4 0.00061 20.0 0.2 9.1 3 3 6 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEZ39093.1 - 2.1e-15 57.0 0.0 4.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KEZ39093.1 - 8.1e-09 34.7 13.4 0.15 10.7 0.0 7.0 6 2 1 8 8 8 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ39093.1 - 4.3e-08 32.5 13.3 0.43 9.5 0.0 6.9 2 2 3 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KEZ39093.1 - 1.4e-05 24.1 12.8 0.44 9.2 0.0 6.0 2 1 3 5 5 5 3 Nup133 N terminal like Nbas_N PF15492.6 KEZ39093.1 - 0.00027 20.4 16.9 1.5 8.1 0.1 8.2 4 2 5 10 10 10 2 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KEZ39093.1 - 0.00045 19.4 13.0 0.18 10.9 0.2 6.0 2 2 6 8 8 8 1 Protein of unknown function (DUF1513) WD40_like PF17005.5 KEZ39093.1 - 0.00061 19.2 4.9 0.2 10.9 0.0 3.8 4 0 0 4 4 4 2 WD40-like domain RNA_helicase PF00910.22 KEZ39093.1 - 0.015 15.7 0.0 0.055 13.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KEZ39093.1 - 0.03 14.7 0.0 0.14 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DUF745 PF05335.13 KEZ39093.1 - 0.031 14.0 3.9 0.82 9.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) baeRF_family2 PF18844.1 KEZ39093.1 - 0.031 14.3 0.1 0.18 11.9 0.1 2.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 DUF3107 PF11305.8 KEZ39093.1 - 0.089 13.1 2.4 0.52 10.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Peptidase_M16_C PF05193.21 KEZ39094.1 - 1.2e-22 80.8 0.0 1.1e-17 64.6 0.0 3.5 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEZ39094.1 - 2.7e-07 30.7 0.0 1e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KEZ39094.1 - 0.0013 17.9 4.8 0.47 9.5 3.2 2.3 2 0 0 2 2 2 2 Peptidase M16C associated CTD_bind PF04818.13 KEZ39095.1 - 3.1e-13 50.3 0.1 2.1e-12 47.7 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. SRP-alpha_N PF04086.13 KEZ39095.1 - 0.093 12.6 6.6 0.16 11.8 6.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SOBP PF15279.6 KEZ39095.1 - 8.8 6.8 36.1 18 5.8 36.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein B56 PF01603.20 KEZ39096.1 - 1.2e-192 640.5 7.3 1.4e-192 640.3 7.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KEZ39096.1 - 0.00024 21.1 2.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Dynamin_N PF00350.23 KEZ39096.1 - 0.07 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Dynamin family rhaM PF05336.13 KEZ39096.1 - 0.084 12.9 0.1 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 L-rhamnose mutarotase Tau95 PF09734.9 KEZ39097.1 - 6.1e-36 124.3 0.1 1.4e-35 123.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KEZ39097.1 - 8.9e-35 119.6 0.0 2.7e-34 118.1 0.0 1.9 1 0 0 1 1 1 1 Tau95 Triple barrel domain zf-C2H2 PF00096.26 KEZ39098.1 - 1.7e-11 43.9 23.7 0.053 14.0 0.0 5.7 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ39098.1 - 3.7e-10 39.8 19.7 0.14 13.1 0.2 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEZ39098.1 - 0.00033 20.6 17.7 0.0018 18.3 0.3 4.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KEZ39098.1 - 0.0015 18.3 1.7 8.9 6.3 0.0 3.6 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KEZ39098.1 - 0.0023 18.2 3.0 0.69 10.3 2.3 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 KEZ39098.1 - 0.0057 16.9 2.4 0.0057 16.9 2.4 2.9 2 1 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KEZ39098.1 - 0.0095 16.2 15.1 1.5 9.2 0.2 4.7 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding DUF4503 PF14951.6 KEZ39098.1 - 0.12 10.8 1.7 0.18 10.2 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Tmemb_55A PF09788.9 KEZ39098.1 - 0.15 11.1 0.3 0.39 9.8 0.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 55A XPA_N PF01286.18 KEZ39098.1 - 0.22 11.6 4.1 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 KEZ39098.1 - 0.24 11.2 7.0 17 5.3 0.6 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KEZ39098.1 - 0.31 11.2 10.4 0.17 12.0 0.4 3.6 3 0 0 3 3 3 0 Zinc ribbon domain Thioredoxin_4 PF13462.6 KEZ39098.1 - 0.4 10.8 1.6 9.3 6.4 0.0 2.6 3 0 0 3 3 2 0 Thioredoxin zf_ZIC PF18366.1 KEZ39098.1 - 0.54 10.4 5.3 0.33 11.1 0.3 2.8 3 0 0 3 3 2 0 Zic proteins zinc finger domain zf-MYST PF17772.1 KEZ39098.1 - 0.9 9.2 4.6 0.13 11.9 0.3 1.8 2 0 0 2 2 2 0 MYST family zinc finger domain zf-H2C2_2 PF13465.6 KEZ39098.1 - 0.98 10.0 16.0 27 5.4 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger double domain zf-LYAR PF08790.11 KEZ39098.1 - 7.2 6.6 6.3 11 6.0 0.1 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DHHC PF01529.20 KEZ39099.1 - 7.8e-39 132.9 8.5 7.8e-39 132.9 8.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase LRS4 PF10422.9 KEZ39099.1 - 0.05 13.2 0.5 0.094 12.3 0.0 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Zw10 PF06248.13 KEZ39100.1 - 1.3e-10 40.6 3.9 2.3e-09 36.4 3.8 2.5 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Peptidase_M48_N PF16491.5 KEZ39101.1 - 2.5e-64 216.5 5.6 2.5e-64 216.5 5.6 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KEZ39101.1 - 4.5e-46 157.1 0.1 7.2e-46 156.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KEZ39101.1 - 0.035 13.3 0.4 0.079 12.1 0.4 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.9 KEZ39101.1 - 0.079 12.8 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 SprT-like family SNF2_N PF00176.23 KEZ39102.1 - 6.3e-36 123.8 0.0 1.4e-35 122.7 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ39102.1 - 7.8e-11 42.3 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ39102.1 - 7.1e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEZ39102.1 - 1.9e-05 24.0 0.0 3.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 KEZ39102.1 - 0.0035 17.2 1.9 0.0069 16.2 1.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEZ39102.1 - 0.018 15.0 4.4 0.036 14.0 4.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEZ39102.1 - 0.11 12.3 6.4 0.23 11.3 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2616 PF11077.8 KEZ39102.1 - 0.15 11.7 1.2 0.42 10.3 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-RING_2 PF13639.6 KEZ39102.1 - 0.83 10.0 5.6 1.6 9.1 5.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 KEZ39102.1 - 2.4 8.1 5.9 5.2 7.0 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L38e PF01781.18 KEZ39103.1 - 4e-33 113.3 1.9 4.7e-33 113.1 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family GHMP_kinases_N PF00288.26 KEZ39104.1 - 1.3e-16 60.5 0.0 3.2e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KEZ39104.1 - 1e-08 35.4 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KEZ39104.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 KEZ39105.1 - 8.3e-36 120.7 19.7 3.3e-07 29.8 0.2 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.6 KEZ39105.1 - 0.13 12.8 3.0 7.4 7.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ39105.1 - 0.21 11.8 3.0 0.56 10.5 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat NTF2 PF02136.20 KEZ39106.1 - 9.5e-05 23.0 0.6 0.0017 18.9 0.6 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain E1-E2_ATPase PF00122.20 KEZ39107.1 - 5.8e-25 87.9 0.2 8.6e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEZ39107.1 - 0.0007 19.4 0.6 0.0007 19.4 0.6 2.1 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus EI24 PF07264.11 KEZ39107.1 - 0.18 12.1 8.2 0.42 10.8 8.2 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) MPS-4 PF17523.2 KEZ39107.1 - 8.5 6.6 6.9 4.8 7.4 0.7 2.9 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 MFS_1 PF07690.16 KEZ39108.1 - 3.7e-33 114.9 32.3 9.3e-25 87.3 9.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39108.1 - 6.3e-06 25.3 16.6 1.1e-05 24.5 2.0 3.9 3 1 1 4 4 4 1 Sugar (and other) transporter ATG22 PF11700.8 KEZ39108.1 - 0.00016 20.5 2.1 0.19 10.3 0.3 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KEZ39108.1 - 0.0025 16.8 0.3 0.0062 15.4 0.0 1.7 2 0 0 2 2 2 1 MFS_1 like family DUF1582 PF07621.11 KEZ39109.1 - 0.026 14.4 0.1 0.066 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) TPR_12 PF13424.6 KEZ39110.1 - 2.7e-08 34.0 9.9 0.61 10.4 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ39110.1 - 4.1e-08 33.8 3.9 7.2e-07 29.7 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain TPR_19 PF14559.6 KEZ39110.1 - 6.2e-05 23.4 2.2 2.2 8.9 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.12 KEZ39110.1 - 0.00034 20.6 0.1 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ39110.1 - 0.001 19.3 0.1 0.017 15.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain TPR_10 PF13374.6 KEZ39110.1 - 0.017 15.0 6.5 3.7 7.6 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ39110.1 - 0.029 13.6 0.0 0.093 11.9 0.0 1.9 1 0 0 1 1 1 0 NB-ARC domain DUF1955 PF09205.10 KEZ39110.1 - 0.074 12.8 0.1 4.1 7.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) TPR_7 PF13176.6 KEZ39110.1 - 0.086 12.9 2.8 30 4.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Phage_holin_5_2 PF16079.5 KEZ39112.1 - 0.0031 17.8 4.9 1.2 9.5 0.9 3.2 2 1 1 3 3 3 2 Phage holin family Hol44, in holin superfamily V Methyltransf_2 PF00891.18 KEZ39113.1 - 3.7e-17 62.3 0.0 5.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KEZ39113.1 - 0.00096 19.1 0.0 0.0073 16.3 0.0 2.3 3 0 0 3 3 3 1 Dimerisation domain MarR_2 PF12802.7 KEZ39113.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 KEZ39113.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 KEZ39113.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DJ-1_PfpI PF01965.24 KEZ39115.1 - 3.4e-10 40.0 0.0 4.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1996 PF09362.10 KEZ39116.1 - 1.2e-78 264.3 0.4 1.5e-78 264.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ferric_reduct PF01794.19 KEZ39117.1 - 1.5e-22 80.0 13.7 1.5e-22 80.0 13.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEZ39117.1 - 5.6e-06 26.6 0.7 0.15 12.2 0.0 3.0 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEZ39117.1 - 1.6e-05 25.0 0.2 0.064 13.3 0.0 2.8 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_1 PF00175.21 KEZ39117.1 - 0.14 12.8 0.1 2.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain AAA_12 PF13087.6 KEZ39118.1 - 7.7e-42 143.2 0.0 2.4e-41 141.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ39118.1 - 1.2e-40 138.9 1.0 4.4e-12 46.6 0.0 6.7 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KEZ39118.1 - 4.9e-27 95.3 27.1 1.8e-24 87.0 0.0 5.9 6 0 0 6 6 5 2 AAA domain AAA_30 PF13604.6 KEZ39118.1 - 5.7e-21 75.1 1.8 1.2e-05 25.1 0.1 5.8 5 0 0 5 5 5 5 AAA domain AAA_lid_6 PF17866.1 KEZ39118.1 - 3.9e-20 71.8 8.4 1.3e-08 34.8 0.5 4.3 3 0 0 3 3 3 2 AAA lid domain AAA_19 PF13245.6 KEZ39118.1 - 6.3e-18 65.5 2.1 1.8e-08 34.8 0.0 5.5 5 1 0 5 5 4 4 AAA domain AAA_22 PF13401.6 KEZ39118.1 - 3.4e-11 43.6 10.3 0.03 14.6 0.0 8.0 5 3 0 5 5 4 3 AAA domain AAA_5 PF07728.14 KEZ39118.1 - 9.8e-11 41.8 1.5 0.095 12.7 0.0 5.1 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KEZ39118.1 - 1.6e-09 37.8 1.3 0.019 14.7 0.0 6.1 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KEZ39118.1 - 2.6e-09 37.7 10.1 0.16 12.3 0.1 7.1 7 1 0 7 7 7 3 AAA ATPase domain RuvB_N PF05496.12 KEZ39118.1 - 1.5e-08 34.6 0.3 0.034 13.9 0.0 4.4 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KEZ39118.1 - 3.4e-08 33.1 0.5 0.074 12.4 0.0 4.7 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KEZ39118.1 - 5.4e-08 32.8 3.2 1.5 8.5 0.1 5.1 4 0 0 4 4 4 3 AAA domain IstB_IS21 PF01695.17 KEZ39118.1 - 5e-07 29.6 0.1 0.99 9.1 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KEZ39118.1 - 2.2e-06 28.0 1.5 4.5 7.7 0.0 5.5 5 1 0 5 5 4 1 RNA helicase ATPase PF06745.13 KEZ39118.1 - 1e-05 25.0 5.4 0.002 17.6 0.0 4.4 5 0 0 5 5 4 1 KaiC Torsin PF06309.11 KEZ39118.1 - 2.3e-05 24.5 0.0 4.8 7.3 0.0 4.7 4 0 0 4 4 4 1 Torsin ResIII PF04851.15 KEZ39118.1 - 2.8e-05 24.2 3.7 0.014 15.4 0.0 5.3 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KEZ39118.1 - 5.3e-05 22.8 0.5 4.1 6.8 0.0 4.7 4 0 0 4 4 4 1 PhoH-like protein AAA_7 PF12775.7 KEZ39118.1 - 0.0003 20.4 0.4 6.9 6.1 0.0 4.3 4 0 0 4 4 4 0 P-loop containing dynein motor region AAA_33 PF13671.6 KEZ39118.1 - 0.00036 20.7 14.2 0.57 10.3 0.0 5.4 5 0 0 5 5 4 1 AAA domain Helicase_RecD PF05127.14 KEZ39118.1 - 0.0013 18.6 0.3 0.46 10.3 0.0 3.5 3 0 0 3 3 2 1 Helicase AAA_2 PF07724.14 KEZ39118.1 - 0.015 15.4 2.2 3.3 7.8 0.0 4.2 5 0 0 5 5 4 0 AAA domain (Cdc48 subfamily) AAA_10 PF12846.7 KEZ39118.1 - 0.019 13.9 1.1 0.18 10.7 0.0 2.9 4 0 0 4 4 4 0 AAA-like domain Guanylate_cyc_2 PF09778.9 KEZ39118.1 - 0.031 13.6 0.0 3.7 6.9 0.0 2.8 2 0 0 2 2 2 0 Guanylylate cyclase DUF2075 PF09848.9 KEZ39118.1 - 0.032 13.5 0.0 0.032 13.5 0.0 6.6 8 0 0 8 8 8 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 KEZ39118.1 - 0.1 12.9 14.9 2.1 8.6 0.1 5.3 5 0 0 5 5 5 0 AAA domain AAA_18 PF13238.6 KEZ39118.1 - 0.11 13.1 23.0 8 7.0 0.0 6.3 6 0 0 6 6 4 0 AAA domain SRP54 PF00448.22 KEZ39118.1 - 0.12 12.0 2.2 1.8 8.1 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KEZ39118.1 - 0.34 10.8 7.1 23 4.8 0.1 4.4 5 0 0 5 5 5 0 NTPase MCM_bind PF09739.9 KEZ39118.1 - 1.1 7.6 7.2 1.9 6.8 7.2 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CbiA PF01656.23 KEZ39118.1 - 5.8 7.0 6.2 1e+02 3.0 0.0 4.7 5 0 0 5 5 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 KEZ39118.1 - 8.4 6.9 12.1 42 4.6 0.1 5.3 4 1 1 5 5 4 0 ABC transporter AMP-binding PF00501.28 KEZ39119.1 - 1.2e-285 946.6 0.0 3.5e-74 249.9 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KEZ39119.1 - 2.1e-183 610.2 0.0 4e-83 279.6 0.0 5.9 5 2 0 5 5 5 4 Condensation domain PP-binding PF00550.25 KEZ39119.1 - 6e-57 189.9 0.1 1.5e-13 50.8 0.0 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ39119.1 - 8.5e-22 77.9 0.0 1.3e-08 35.7 0.0 4.9 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain DUF547 PF04784.14 KEZ39119.1 - 0.043 13.8 0.0 2 8.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF547 Collagen PF01391.18 KEZ39119.1 - 1.3 8.8 9.7 0.7 9.7 1.0 3.4 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 KEZ39120.1 - 3.2e-40 138.1 18.4 3.2e-40 138.1 18.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KEZ39120.1 - 0.0069 16.2 0.6 0.53 10.1 0.0 2.8 2 2 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SpoVAB PF13782.6 KEZ39120.1 - 0.039 14.2 0.2 0.039 14.2 0.2 2.8 2 2 0 2 2 2 0 Stage V sporulation protein AB DUF983 PF06170.12 KEZ39120.1 - 6.2 7.3 7.6 4.8 7.7 1.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Fungal_trans PF04082.18 KEZ39121.1 - 1.3e-36 126.0 0.5 1.8e-36 125.6 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NMT1 PF09084.11 KEZ39122.1 - 0.084 12.8 0.0 5.5 6.9 0.0 2.5 2 1 0 2 2 2 0 NMT1/THI5 like p450 PF00067.22 KEZ39123.1 - 9.5e-35 120.2 0.0 1.2e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2312 PF10073.9 KEZ39123.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) GMC_oxred_N PF00732.19 KEZ39126.1 - 3.7e-46 157.8 0.0 4.9e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39126.1 - 1.5e-26 93.7 0.0 2.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEZ39126.1 - 0.0027 16.8 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ39126.1 - 0.023 14.0 0.0 0.047 12.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KEZ39126.1 - 0.055 12.3 0.2 0.096 11.5 0.0 1.4 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KEZ39126.1 - 0.079 13.2 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ39126.1 - 0.085 11.9 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain PAP_PilO PF06864.12 KEZ39127.1 - 0.11 11.3 0.5 0.31 9.8 0.1 1.8 2 0 0 2 2 2 0 Pilin accessory protein (PilO) His_Phos_2 PF00328.22 KEZ39128.1 - 8.3e-30 104.4 0.0 1.6e-29 103.5 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_hydro_16 PF00722.21 KEZ39129.1 - 5.5e-07 29.2 0.1 8.1e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 KEZ39129.1 - 0.00074 19.7 0.1 0.0011 19.2 0.1 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Pyrophosphatase PF00719.19 KEZ39130.1 - 6.5e-47 159.3 0.0 8.9e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF1996 PF09362.10 KEZ39131.1 - 3.6e-81 272.6 0.9 4.4e-81 272.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Phytase-like PF13449.6 KEZ39132.1 - 4.2e-35 122.1 0.1 6.6e-35 121.4 0.1 1.4 1 1 0 1 1 1 1 Esterase-like activity of phytase FAD_binding_3 PF01494.19 KEZ39133.1 - 1.7e-28 99.9 0.1 8.6e-28 97.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEZ39133.1 - 5.7e-07 29.1 0.0 1.7e-05 24.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ39133.1 - 5.6e-06 26.2 0.1 8.4e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ39133.1 - 6.4e-06 25.6 0.1 0.0004 19.7 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ39133.1 - 0.00013 22.1 0.2 0.00033 20.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KEZ39133.1 - 0.0031 17.6 0.1 0.0064 16.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KEZ39133.1 - 0.0043 16.2 0.0 0.0099 15.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain ThiF PF00899.21 KEZ39133.1 - 0.0078 15.6 0.4 0.013 14.9 0.4 1.3 1 0 0 1 1 1 1 ThiF family HI0933_like PF03486.14 KEZ39133.1 - 0.013 14.2 0.1 0.048 12.4 0.1 1.9 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KEZ39133.1 - 0.013 16.0 1.5 0.059 13.9 0.5 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ39133.1 - 0.015 14.2 0.6 0.52 9.1 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KEZ39133.1 - 0.017 15.1 0.3 0.33 10.9 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ39133.1 - 0.027 13.5 0.3 0.14 11.1 0.3 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KEZ39133.1 - 0.029 14.6 0.1 0.088 13.1 0.1 1.8 2 0 0 2 2 1 0 TrkA-N domain SEO_C PF14577.6 KEZ39133.1 - 0.03 13.8 0.3 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 Sieve element occlusion C-terminus Thi4 PF01946.17 KEZ39133.1 - 0.041 13.1 0.3 0.071 12.3 0.3 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 KEZ39133.1 - 0.051 13.2 0.4 0.092 12.4 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 KEZ39133.1 - 0.21 10.9 0.4 17 4.6 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase GIDA PF01134.22 KEZ39133.1 - 0.21 10.6 0.3 0.94 8.5 0.3 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A Transferase PF02458.15 KEZ39134.1 - 2.3e-09 36.4 0.0 1.5e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Transferase family Inhibitor_I36 PF03995.13 KEZ39135.1 - 0.0029 17.5 7.5 0.0032 17.4 4.9 2.2 1 1 2 3 3 3 1 Peptidase inhibitor family I36 Crystall_3 PF08964.10 KEZ39135.1 - 0.0065 16.6 0.4 0.01 16.0 0.4 1.4 1 1 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.19 KEZ39135.1 - 0.023 14.9 0.5 2.1 8.6 0.1 2.2 2 1 0 2 2 2 0 Beta/Gamma crystallin Arginase PF00491.21 KEZ39136.1 - 4.2e-77 259.4 0.0 5.6e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KEZ39136.1 - 0.047 13.9 0.1 0.074 13.3 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain BBP2_2 PF10082.9 KEZ39136.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Putative beta-barrel porin 2 Defensin_propep PF00879.18 KEZ39136.1 - 1.9 8.8 4.4 4.3 7.7 4.4 1.6 1 0 0 1 1 1 0 Defensin propeptide NmrA PF05368.13 KEZ39138.1 - 1.9e-31 109.4 0.0 2.2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ39138.1 - 1.6e-12 47.7 0.0 2.9e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEZ39138.1 - 2.8e-08 34.1 0.0 5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEZ39138.1 - 4.3e-05 24.0 0.1 7.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEZ39138.1 - 0.017 14.6 0.1 0.15 11.5 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pox_Ag35 PF03286.14 KEZ39138.1 - 0.056 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KR PF08659.10 KEZ39138.1 - 0.12 12.2 0.1 0.25 11.2 0.0 1.5 2 0 0 2 2 2 0 KR domain DUF4360 PF14273.6 KEZ39139.1 - 9.2e-48 162.5 0.0 2.3e-47 161.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) Fungal_trans PF04082.18 KEZ39139.1 - 4.3e-09 35.8 4.6 6.8e-09 35.1 4.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 KEZ39140.1 - 3e-08 33.8 0.0 6.6e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Ricin_B_lectin PF00652.22 KEZ39141.1 - 6.9e-16 58.7 4.1 2.4e-09 37.5 0.2 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KEZ39141.1 - 6.8e-09 36.3 4.6 1e-05 26.1 0.2 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Sugar_tr PF00083.24 KEZ39142.1 - 3.3e-76 257.0 15.3 3.8e-76 256.8 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39142.1 - 1.8e-29 102.8 20.0 1.1e-26 93.6 10.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ39142.1 - 0.00027 20.4 3.0 0.00027 20.4 3.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 KEZ39142.1 - 0.0003 19.7 3.3 0.00061 18.7 0.2 2.1 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_2 PF13347.6 KEZ39142.1 - 0.00053 18.7 6.6 0.00053 18.7 6.6 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein YrhK PF14145.6 KEZ39142.1 - 0.016 15.1 0.8 0.016 15.1 0.8 2.5 3 0 0 3 3 3 0 YrhK-like protein DUF1700 PF08006.11 KEZ39142.1 - 0.17 11.4 1.7 0.57 9.7 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) OATP PF03137.20 KEZ39142.1 - 0.3 9.3 10.4 1.3 7.2 0.5 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF1996 PF09362.10 KEZ39143.1 - 4.8e-77 259.1 1.4 5.8e-77 258.8 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF5566 PF17721.1 KEZ39143.1 - 0.028 14.7 0.2 0.045 14.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5566) NAD_binding_6 PF08030.12 KEZ39144.1 - 8.1e-19 68.3 0.0 1.7e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KEZ39144.1 - 2e-15 57.0 14.8 2e-15 57.0 14.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEZ39144.1 - 3.4e-13 49.6 0.0 7.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KEZ39144.1 - 0.0088 16.7 0.0 0.073 13.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain UcrQ PF02939.16 KEZ39144.1 - 0.053 13.5 0.1 6.2 6.8 0.5 3.2 3 0 0 3 3 3 0 UcrQ family MFS_1 PF07690.16 KEZ39145.1 - 4.5e-13 48.8 54.2 1.1e-07 31.2 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydr_30_2 PF14587.6 KEZ39146.1 - 7.2e-16 58.7 2.0 6.4e-14 52.3 0.0 2.3 1 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 KEZ39146.1 - 5.1e-15 55.5 0.1 7.9e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 KEZ39146.1 - 2e-13 50.4 7.1 1.9e-11 44.0 7.1 3.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 KEZ39146.1 - 1.6e-09 37.2 0.1 7.1e-09 35.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain DUF3632 PF12311.8 KEZ39147.1 - 5.6e-24 85.5 1.1 7.8e-24 85.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FMO-like PF00743.19 KEZ39149.1 - 1.1e-22 80.2 0.0 1.2e-11 43.7 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ39149.1 - 4e-08 32.9 0.0 3.5e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ39149.1 - 2e-05 23.9 0.2 0.0012 18.0 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ39149.1 - 0.004 16.4 0.0 0.0076 15.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ39150.1 - 6.5e-12 45.5 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEZ39150.1 - 6.2e-11 42.2 0.0 9.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KEZ39150.1 - 5.6e-07 29.1 0.1 8.6e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KEZ39150.1 - 2.3e-06 27.0 0.2 4.2e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ39150.1 - 3e-06 26.7 0.1 4.3e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ39150.1 - 3.3e-06 26.1 1.0 5e-06 25.5 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KEZ39150.1 - 9.5e-06 25.0 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KEZ39150.1 - 1.1e-05 25.1 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ39150.1 - 2.1e-05 23.9 0.2 3.6e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ39150.1 - 0.00018 21.2 0.0 0.0009 18.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ39150.1 - 0.0035 17.9 0.1 0.0068 16.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ39150.1 - 0.01 15.1 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEZ39150.1 - 0.019 14.0 0.5 0.029 13.5 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 KEZ39150.1 - 0.07 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 KEZ39150.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding IlvN PF07991.12 KEZ39150.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 KEZ39150.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 KEZ39150.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding FMO-like PF00743.19 KEZ39150.1 - 0.23 9.8 0.1 0.32 9.4 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 KEZ39150.1 - 0.24 10.4 0.3 0.35 9.9 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ADH_zinc_N PF00107.26 KEZ39151.1 - 7.8e-27 93.8 1.2 1.3e-26 93.1 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ39151.1 - 1.1e-14 55.6 0.0 2.5e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ39151.1 - 0.0003 20.6 0.1 0.0009 19.1 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KEZ39151.1 - 0.0057 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 KEZ39151.1 - 0.023 14.6 0.0 0.14 12.0 0.0 2.1 1 1 1 2 2 2 0 N-terminal domain of oxidoreductase MFS_1 PF07690.16 KEZ39152.1 - 1.3e-16 60.5 7.5 1.9e-16 59.9 7.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39152.1 - 0.0014 17.6 8.5 0.0026 16.7 8.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ39152.1 - 0.0026 16.7 8.2 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 KEZ39152.1 - 1.2 7.4 9.7 0.3 9.4 5.9 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 KEZ39152.1 - 1.8 6.8 5.7 3.8 5.7 5.7 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 KEZ39153.1 - 2.3e-42 145.1 0.0 3.4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KEZ39153.1 - 0.00036 20.4 0.6 0.00073 19.4 0.6 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus FAA_hydrolase PF01557.18 KEZ39154.1 - 7.5e-32 110.8 0.0 1.1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF5612 PF18462.1 KEZ39154.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) p450 PF00067.22 KEZ39155.1 - 1.3e-65 222.0 0.0 4.7e-63 213.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 2-oxoacid_dh PF00198.23 KEZ39156.1 - 2.9e-66 223.3 0.1 4.5e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEZ39156.1 - 3e-17 62.2 0.0 5.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEZ39156.1 - 3.3e-14 52.9 0.1 8.6e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KEZ39156.1 - 0.013 15.3 0.0 0.39 10.6 0.0 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_D23 PF16576.5 KEZ39156.1 - 0.04 13.1 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion E1_dh PF00676.20 KEZ39157.1 - 1.6e-74 250.6 0.0 2.1e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEZ39157.1 - 0.052 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase EnY2 PF10163.9 KEZ39157.1 - 0.15 12.5 0.6 0.28 11.6 0.6 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 Transket_pyr PF02779.24 KEZ39158.1 - 8.6e-43 146.1 0.0 1.2e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ39158.1 - 1.1e-31 109.3 0.0 2.1e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_3 PF01494.19 KEZ39159.1 - 1e-64 219.0 0.0 1.6e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KEZ39159.1 - 8.3e-06 26.3 0.0 0.09 13.4 0.0 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ39159.1 - 0.0011 18.3 0.0 0.4 9.9 0.0 2.8 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ39159.1 - 0.008 15.8 0.0 2.5 7.6 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Glyco_transf_21 PF13506.6 KEZ39160.1 - 0.006 16.1 0.1 0.0096 15.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1664 PF07889.12 KEZ39160.1 - 0.085 12.9 0.1 0.26 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Flagellin_N PF00669.20 KEZ39160.1 - 0.15 12.2 0.9 0.31 11.1 0.2 1.8 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF948 PF06103.11 KEZ39160.1 - 0.17 12.1 7.7 5.2 7.4 4.8 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FIVAR PF07554.13 KEZ39160.1 - 1.2 10.0 9.1 2.7 8.8 0.6 2.4 2 0 0 2 2 2 0 FIVAR domain Fer4_19 PF06902.11 KEZ39161.1 - 0.32 11.1 2.4 0.63 10.2 2.4 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster DUF2196 PF09962.9 KEZ39162.1 - 2.5e-22 78.6 5.4 4.1e-22 77.9 5.4 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Methyltransf_24 PF13578.6 KEZ39163.1 - 5.8e-12 46.6 0.0 1.1e-11 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KEZ39163.1 - 1.9e-07 30.5 0.0 4.9e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.16 KEZ39164.1 - 2.2e-15 56.4 15.6 9.1e-11 41.3 5.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 KEZ39165.1 - 4e-40 137.5 0.0 1.5e-28 100.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEZ39165.1 - 2.2e-14 53.8 3.1 2.2e-14 53.8 3.1 3.0 3 1 0 3 3 3 1 ABC transporter transmembrane region AAA_21 PF13304.6 KEZ39165.1 - 2.6e-05 24.2 0.3 0.017 15.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEZ39165.1 - 8.3e-05 22.9 0.6 0.0065 16.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 KEZ39165.1 - 0.00018 21.1 0.1 0.033 13.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KEZ39165.1 - 0.00043 20.7 0.2 0.002 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ39165.1 - 0.0005 20.0 0.7 0.0036 17.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Guanylate_kin PF00625.21 KEZ39165.1 - 0.00068 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 KEZ39165.1 - 0.0012 18.9 0.0 0.081 13.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KEZ39165.1 - 0.0016 17.5 0.5 0.12 11.4 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 KEZ39165.1 - 0.002 18.5 0.1 0.017 15.5 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KEZ39165.1 - 0.0035 17.4 0.6 0.0057 16.7 0.0 1.7 2 0 0 2 2 1 1 Dynamin family AAA_29 PF13555.6 KEZ39165.1 - 0.0036 17.0 2.5 0.41 10.4 0.4 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KEZ39165.1 - 0.0048 16.5 0.3 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KEZ39165.1 - 0.0054 16.2 3.7 1.6 8.1 0.1 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KEZ39165.1 - 0.0054 17.3 0.0 0.27 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KEZ39165.1 - 0.0056 17.2 0.2 0.14 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 KEZ39165.1 - 0.0084 15.9 0.5 0.017 14.9 0.0 1.8 2 0 0 2 2 1 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KEZ39165.1 - 0.014 14.6 0.2 0.043 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KEZ39165.1 - 0.021 14.0 0.8 0.23 10.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.21 KEZ39165.1 - 0.022 14.1 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEZ39165.1 - 0.025 14.7 1.5 0.056 13.6 0.1 2.3 3 0 0 3 3 1 0 AAA domain AAA_14 PF13173.6 KEZ39165.1 - 0.028 14.4 0.0 0.093 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ39165.1 - 0.05 12.9 0.7 0.094 12.0 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KEZ39165.1 - 0.059 13.6 0.2 0.96 9.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KEZ39165.1 - 0.065 12.9 3.0 0.26 11.0 0.1 2.7 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 KEZ39165.1 - 0.069 13.1 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 KEZ39165.1 - 0.08 12.9 0.3 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KEZ39165.1 - 0.1 12.2 0.9 0.14 11.8 0.0 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 KEZ39165.1 - 0.14 12.2 0.8 0.43 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEZ39165.1 - 0.15 12.5 0.1 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 KEZ39165.1 - 0.19 11.4 1.1 0.46 10.1 0.2 2.1 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KEZ39165.1 - 0.62 10.0 3.2 0.75 9.7 0.2 2.6 3 0 0 3 3 3 0 NACHT domain AA_permease_2 PF13520.6 KEZ39166.1 - 2.7e-88 296.7 39.3 3.4e-88 296.3 39.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ39166.1 - 3.6e-19 68.7 30.4 5.1e-19 68.2 30.4 1.2 1 0 0 1 1 1 1 Amino acid permease YCII PF03795.14 KEZ39167.1 - 9.8e-11 41.9 0.0 1.6e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 YCII-related domain Abhydrolase_4 PF08386.10 KEZ39168.1 - 1e-19 70.6 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEZ39168.1 - 2.9e-12 46.8 0.0 1.9e-10 40.8 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 KEZ39169.1 - 3.6e-09 36.0 0.0 5.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Suppressor_APC PF11414.8 KEZ39169.1 - 0.14 12.2 0.2 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein MFS_1 PF07690.16 KEZ39170.1 - 7.8e-21 74.4 24.4 1e-20 74.0 24.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39170.1 - 3.3e-16 59.2 12.2 5.4e-16 58.5 12.2 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TPR_19 PF14559.6 KEZ39170.1 - 0.042 14.4 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_11 PF00457.17 KEZ39171.1 - 1.5e-79 265.8 21.3 1.7e-79 265.6 21.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ribosomal_S16 PF00886.19 KEZ39171.1 - 0.092 12.8 0.4 1.6 8.8 0.1 2.7 1 1 1 2 2 2 0 Ribosomal protein S16 GMC_oxred_N PF00732.19 KEZ39176.1 - 6.5e-68 229.3 0.0 8.7e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39176.1 - 1.5e-27 96.9 0.0 2.4e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ39176.1 - 6.3e-06 25.5 0.5 0.085 11.9 0.5 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KEZ39176.1 - 8.8e-06 25.0 0.4 8.8e-06 25.0 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ39176.1 - 0.00083 18.7 0.2 0.00083 18.7 0.2 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KEZ39176.1 - 0.026 14.1 1.7 0.17 11.4 0.3 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KEZ39176.1 - 0.074 11.9 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KEZ39176.1 - 0.12 11.6 0.9 0.23 10.7 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ39176.1 - 0.16 11.9 0.1 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HET PF06985.11 KEZ39177.1 - 0.0014 19.0 0.0 0.0031 17.9 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEZ39178.1 - 4.2e-24 85.0 0.0 1.5e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ39178.1 - 2.2e-20 72.4 0.2 4.7e-06 26.8 0.0 5.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEZ39178.1 - 2.7e-20 71.8 0.9 2.5e-05 24.5 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KEZ39178.1 - 5.1e-20 71.6 0.0 0.00045 20.7 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ39178.1 - 2.2e-17 61.3 0.1 2.2e-05 24.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat TPR_8 PF13181.6 KEZ39178.1 - 9.3e-05 22.4 1.1 0.07 13.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ39178.1 - 0.013 15.8 0.1 0.91 9.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SesA PF17107.5 KEZ39178.1 - 0.092 12.9 0.0 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_2 PF07719.17 KEZ39178.1 - 0.1 12.8 0.8 9.2 6.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KEZ39179.1 - 2.7e-63 214.4 0.2 3.9e-63 213.9 0.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 KEZ39180.1 - 4.6e-06 25.9 0.0 2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 KEZ39181.1 - 1.5e-85 287.1 26.6 2e-44 152.3 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ39181.1 - 3.2e-70 235.0 0.0 1.6e-34 119.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ39181.1 - 1.6e-11 44.0 7.5 8.8e-05 22.0 1.1 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ39181.1 - 6.2e-08 33.2 2.1 0.0014 19.0 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KEZ39181.1 - 6.8e-08 32.1 1.1 0.0017 18.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ39181.1 - 1.8e-07 31.5 0.6 0.038 14.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KEZ39181.1 - 5.1e-07 29.2 0.1 0.12 11.6 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 KEZ39181.1 - 1e-06 28.8 0.2 0.057 13.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KEZ39181.1 - 1.1e-06 27.8 4.2 0.005 15.7 0.1 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KEZ39181.1 - 5.2e-05 23.0 2.4 0.69 9.6 0.1 4.0 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.6 KEZ39181.1 - 7.7e-05 22.6 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KEZ39181.1 - 0.0001 22.2 3.5 3 7.6 0.0 4.1 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KEZ39181.1 - 0.00023 20.4 0.0 0.48 9.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 KEZ39181.1 - 0.0006 19.5 0.7 0.57 9.7 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KEZ39181.1 - 0.0013 19.2 2.6 0.52 10.8 0.1 2.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 KEZ39181.1 - 0.0018 18.3 0.5 5.7 6.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ39181.1 - 0.0021 17.6 0.1 0.4 10.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 KEZ39181.1 - 0.0024 18.0 2.2 2.3 8.5 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KEZ39181.1 - 0.0029 18.0 0.1 9.5 6.7 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DUF2080 PF09853.9 KEZ39181.1 - 0.013 15.2 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) ATP-synt_ab PF00006.25 KEZ39181.1 - 0.014 15.1 0.0 0.46 10.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KEZ39181.1 - 0.023 13.9 0.3 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.18 KEZ39181.1 - 0.024 14.4 0.1 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 KEZ39181.1 - 0.028 14.3 0.1 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 KEZ39181.1 - 0.055 13.4 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KEZ39181.1 - 0.062 13.4 0.3 6.2 6.9 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 KEZ39181.1 - 0.064 13.1 0.2 7.1 6.5 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase DUF815 PF05673.13 KEZ39181.1 - 0.067 12.3 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KEZ39181.1 - 0.092 12.8 0.0 36 4.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KEZ39181.1 - 0.099 12.7 0.8 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 KEZ39181.1 - 0.11 13.1 0.0 13 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEZ39181.1 - 0.13 12.4 1.9 21 5.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF2207 PF09972.9 KEZ39181.1 - 3.2 6.4 12.8 0.094 11.5 0.1 3.2 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) AA_permease PF00324.21 KEZ39182.1 - 7.2e-122 407.4 42.9 8.9e-122 407.1 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ39182.1 - 4.2e-29 101.6 47.6 5e-29 101.4 47.6 1.1 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.16 KEZ39183.1 - 2.6e-31 109.4 0.1 3.8e-31 108.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.6 KEZ39183.1 - 0.028 14.0 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 0 LssY C-terminus Mg_trans_NIPA PF05653.14 KEZ39184.1 - 1.2e-93 313.5 26.6 1.7e-93 313.0 26.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KEZ39184.1 - 3.7e-06 27.2 7.9 3.7e-06 27.2 7.9 3.3 3 0 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 KEZ39184.1 - 0.0035 16.9 4.2 0.0035 16.9 4.2 2.3 1 1 0 2 2 2 1 Solute carrier family 35 Polysacc_deac_1 PF01522.21 KEZ39185.1 - 4.1e-27 94.5 0.0 7e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_16 PF00722.21 KEZ39187.1 - 0.00011 21.8 0.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Cu-oxidase_2 PF07731.14 KEZ39188.1 - 1.1e-46 158.0 5.7 3.1e-40 137.1 2.4 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEZ39188.1 - 1.3e-41 141.3 5.1 2e-40 137.5 0.4 3.8 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 KEZ39188.1 - 8.5e-31 107.2 0.0 3.4e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase DUF4981 PF16353.5 KEZ39188.1 - 0.013 16.0 0.0 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function(DUF4981) Tropomyosin PF00261.20 KEZ39189.1 - 0.0016 17.9 36.5 0.0016 17.9 36.5 5.6 4 1 0 4 4 4 2 Tropomyosin PAM2 PF07145.15 KEZ39189.1 - 0.0032 17.0 13.0 0.81 9.5 1.2 4.6 4 0 0 4 4 4 3 Ataxin-2 C-terminal region DNA_pol_B PF00136.21 KEZ39190.1 - 8.8e-102 341.2 0.0 3.9e-101 339.0 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KEZ39190.1 - 6e-21 74.9 0.1 6.4e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KEZ39190.1 - 5.7e-16 58.7 2.1 1.4e-15 57.5 2.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 KEZ39190.1 - 0.044 13.8 1.2 0.12 12.4 1.2 1.7 1 0 0 1 1 1 0 Double zinc ribbon AAA_lid_10 PF17872.1 KEZ39190.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain Mcp5_PH PF12814.7 KEZ39191.1 - 2e-46 157.1 0.0 4.2e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KEZ39191.1 - 0.00019 21.9 0.0 0.00049 20.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Redoxin PF08534.10 KEZ39192.1 - 0.0016 18.2 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 KEZ39192.1 - 0.0019 18.7 0.0 2 8.9 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KEZ39192.1 - 0.0019 18.2 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 KEZ39192.1 - 0.037 13.7 0.0 0.15 11.7 0.0 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) MFS_1 PF07690.16 KEZ39193.1 - 2.4e-38 132.0 31.3 4.1e-30 104.9 10.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39193.1 - 3.5e-13 49.2 12.5 3.5e-13 49.2 12.5 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ39193.1 - 0.00022 19.8 5.0 0.00045 18.8 5.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 KEZ39193.1 - 0.076 12.8 15.6 0.019 14.8 2.8 3.3 2 1 1 3 3 3 0 Fatty acid desaturase DBP PF12361.8 KEZ39193.1 - 0.38 10.5 3.0 0.57 10.0 3.0 1.1 1 0 0 1 1 1 0 Duffy-antigen binding protein PFK PF00365.20 KEZ39194.1 - 4e-186 617.0 1.5 4.4e-104 347.8 1.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 KEZ39194.1 - 0.15 11.7 0.1 1.3 8.7 0.1 2.5 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain EI24 PF07264.11 KEZ39195.1 - 3.2e-14 53.6 11.7 4.2e-14 53.2 11.7 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-RING_2 PF13639.6 KEZ39196.1 - 4.5e-12 46.1 5.2 7.1e-12 45.5 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 KEZ39196.1 - 2.2e-09 37.2 0.5 6.9e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 PA domain zf-rbx1 PF12678.7 KEZ39196.1 - 1.7e-08 34.6 2.4 3.1e-08 33.8 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEZ39196.1 - 2.2e-08 33.7 2.5 2.2e-08 33.7 2.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEZ39196.1 - 2.4e-08 33.7 3.8 3.7e-08 33.1 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ39196.1 - 3e-08 33.4 3.0 4.7e-08 32.8 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ39196.1 - 7.5e-07 29.0 2.1 1.2e-06 28.4 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEZ39196.1 - 3.9e-05 23.6 1.8 0.00011 22.1 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KEZ39196.1 - 5e-05 23.1 3.1 7.4e-05 22.5 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEZ39196.1 - 0.0045 17.0 1.1 0.0082 16.2 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KEZ39196.1 - 0.018 14.9 2.9 0.03 14.2 2.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEZ39196.1 - 0.12 12.6 4.5 0.43 10.8 4.6 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KEZ39196.1 - 0.26 11.5 2.2 0.71 10.1 2.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KEZ39196.1 - 0.89 9.2 3.2 1.8 8.3 3.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type LANC_like PF05147.13 KEZ39197.1 - 3e-25 88.6 0.0 4.5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein TRP PF06011.12 KEZ39199.1 - 3e-86 289.8 6.4 7.3e-59 199.6 3.4 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEZ39199.1 - 2.8e-28 99.0 0.0 4e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 ML-like domain ATP-sulfurylase PF01747.17 KEZ39200.1 - 1.4e-87 292.7 0.1 1.9e-87 292.2 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KEZ39200.1 - 3.4e-58 196.0 0.0 5.5e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KEZ39200.1 - 4.3e-52 176.0 0.0 6.6e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.6 KEZ39200.1 - 0.17 12.5 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dioxygenase_C PF00775.21 KEZ39201.1 - 3.7e-44 150.3 0.0 5.3e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEZ39201.1 - 1.3e-29 101.8 0.0 2.2e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEZ39201.1 - 0.0039 17.4 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KEZ39201.1 - 0.03 14.3 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) SUI1 PF01253.22 KEZ39202.1 - 5.5e-28 97.3 4.3 7.1e-28 97.0 4.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 EOS1 PF12326.8 KEZ39203.1 - 1.7e-15 57.4 4.9 1.7e-15 57.4 4.9 2.7 2 1 1 3 3 3 1 N-glycosylation protein DUF4728 PF15860.5 KEZ39203.1 - 0.048 14.3 1.7 0.075 13.7 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4728) Tim44 PF04280.15 KEZ39204.1 - 1.7e-08 34.7 0.3 7.4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain MBA1 PF07961.11 KEZ39204.1 - 4.4e-06 25.9 0.0 1.8e-05 23.9 0.0 1.8 1 1 1 2 2 2 1 MBA1-like protein SSF PF00474.17 KEZ39205.1 - 9.3e-06 24.7 31.5 0.00015 20.8 31.5 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family MRAP PF15183.6 KEZ39205.1 - 9.7 6.2 6.1 4.4 7.3 1.1 2.6 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family RRM_1 PF00076.22 KEZ39206.1 - 2.5e-19 68.8 0.0 1.8e-12 46.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEZ39206.1 - 0.035 14.0 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif CIA30 PF08547.12 KEZ39207.1 - 5e-47 159.9 0.0 8.5e-47 159.1 0.0 1.4 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Sas10_Utp3 PF04000.15 KEZ39208.1 - 7.8e-09 36.1 0.5 7.8e-09 36.1 0.5 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF155 PF02582.14 KEZ39208.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Seryl_tRNA_N PF02403.22 KEZ39208.1 - 0.14 12.4 6.8 0.46 10.7 0.2 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2076 PF09849.9 KEZ39210.1 - 8.5e-09 35.8 10.4 1.1e-08 35.5 10.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KEZ39210.1 - 7.6e-05 22.7 4.9 0.00011 22.2 4.9 1.2 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 KEZ39210.1 - 0.0088 16.4 2.1 0.012 16.0 2.1 1.1 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein C-terminal domain GCK PF07802.11 KEZ39210.1 - 0.012 16.0 1.2 0.022 15.2 1.2 1.5 1 1 0 1 1 1 0 GCK domain NPBW PF15180.6 KEZ39210.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Neuropeptides B and W UBX PF00789.20 KEZ39211.1 - 1.6e-09 37.8 0.0 3.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Hamartin PF04388.12 KEZ39211.1 - 0.0018 17.1 11.8 0.0021 16.8 11.8 1.1 1 0 0 1 1 1 1 Hamartin protein Thioredoxin_7 PF13899.6 KEZ39211.1 - 0.0026 17.9 0.1 0.0073 16.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like TFIIA PF03153.13 KEZ39211.1 - 0.07 13.1 10.6 0.13 12.3 10.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 KEZ39211.1 - 0.13 11.6 27.1 0.21 10.9 27.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CENP-U PF13097.6 KEZ39211.1 - 0.45 10.5 14.6 0.26 11.2 12.1 1.9 1 1 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Med13_C PF06333.12 KEZ39211.1 - 1.8 7.7 11.2 3.4 6.8 11.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Nucleo_P87 PF07267.11 KEZ39211.1 - 5.5 5.7 14.0 8.4 5.1 14.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SURF1 PF02104.15 KEZ39212.1 - 2e-48 164.9 0.1 2.8e-48 164.5 0.1 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 KEZ39213.1 - 7.3e-46 154.8 0.0 1.3e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KEZ39213.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KEZ39213.1 - 0.00016 22.0 0.0 0.00051 20.4 0.0 1.9 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEZ39213.1 - 0.00084 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KEZ39213.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 KEZ39213.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Ras PF00071.22 KEZ39214.1 - 4.4e-54 182.4 0.0 5.1e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ39214.1 - 1.9e-21 76.5 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ39214.1 - 2.1e-06 27.3 0.0 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CMS1 PF14617.6 KEZ39215.1 - 1.5e-79 266.9 0.4 1.5e-79 266.9 0.4 4.7 3 1 0 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit RRM_1 PF00076.22 KEZ39215.1 - 6.9e-12 45.0 0.0 1.8e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 KEZ39215.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fumble PF03630.14 KEZ39215.1 - 0.08 12.1 0.1 0.19 10.9 0.1 1.6 1 0 0 1 1 1 0 Fumble RhoGAP PF00620.27 KEZ39216.1 - 3.3e-46 156.9 0.0 9.8e-46 155.3 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KEZ39216.1 - 1.2e-14 54.3 0.3 2.6e-14 53.2 0.3 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 KEZ39216.1 - 0.65 9.3 3.2 1.3 8.3 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med12 PF09497.10 KEZ39217.1 - 6.3e-28 96.9 1.2 3.4e-27 94.5 0.3 2.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 UPF0139 PF03669.13 KEZ39218.1 - 3.8e-06 26.7 0.0 5.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF1097 PF06496.11 KEZ39218.1 - 0.029 14.5 0.2 0.036 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) Asp PF00026.23 KEZ39219.1 - 9.4e-62 209.2 1.1 1.2e-61 208.9 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ39219.1 - 4.1e-17 63.0 0.4 2e-16 60.7 0.4 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEZ39219.1 - 1.1e-05 25.9 0.0 0.6 10.8 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KEZ39219.1 - 2.6e-05 24.7 0.1 0.95 10.1 0.0 3.9 2 2 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KEZ39219.1 - 0.052 13.3 0.1 1.7 8.4 0.0 2.6 2 1 1 3 3 3 0 Xylanase inhibitor C-terminal Mt_ATP-synt_D PF05873.12 KEZ39220.1 - 5.8e-21 75.0 4.9 7e-21 74.7 4.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) LXG PF04740.12 KEZ39220.1 - 0.0029 17.4 4.4 0.0035 17.1 4.4 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily Dor1 PF04124.12 KEZ39220.1 - 0.0045 15.7 2.4 0.0057 15.4 2.4 1.2 1 0 0 1 1 1 1 Dor1-like family Ferritin_2 PF13668.6 KEZ39220.1 - 0.076 13.2 2.4 0.1 12.8 2.4 1.2 1 0 0 1 1 1 0 Ferritin-like domain CheZ PF04344.13 KEZ39220.1 - 0.11 12.4 6.2 0.16 11.9 6.0 1.4 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF148 PF02520.17 KEZ39220.1 - 0.14 12.3 6.5 0.056 13.6 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 Aida_N PF08910.10 KEZ39220.1 - 0.27 11.6 3.3 4.9 7.6 0.8 2.1 1 1 1 2 2 2 0 Aida N-terminus Spectrin PF00435.21 KEZ39220.1 - 0.69 10.4 7.4 2.6 8.6 0.6 2.4 1 1 2 3 3 3 0 Spectrin repeat DUF2408 PF10303.9 KEZ39220.1 - 1.2 9.7 5.4 7.8 7.1 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) APG6_N PF17675.1 KEZ39220.1 - 7.1 7.2 10.8 2.7 8.5 3.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 KEZ39221.1 - 1e-08 35.6 16.1 0.0014 19.4 1.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KEZ39221.1 - 3e-06 26.7 10.6 5.9e-06 25.8 10.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 KEZ39221.1 - 0.0039 17.5 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KEZ39221.1 - 0.066 13.6 5.6 0.15 12.4 5.6 1.6 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.26 KEZ39221.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme UQ_con PF00179.26 KEZ39222.1 - 4.8e-49 165.6 0.0 5.5e-49 165.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ39222.1 - 0.00051 19.8 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KEZ39222.1 - 0.0045 16.8 0.0 0.0092 15.8 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KEZ39222.1 - 0.072 13.4 0.0 0.097 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain ADH_zinc_N PF00107.26 KEZ39223.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ39223.1 - 0.004 17.0 0.0 0.0087 15.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PI3Ka PF00613.20 KEZ39224.1 - 1e-56 191.3 0.3 1.8e-56 190.5 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KEZ39224.1 - 3.3e-47 161.4 0.0 5.5e-33 114.8 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KEZ39224.1 - 5e-35 120.4 0.0 9e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF928 PF06051.12 KEZ39224.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Nse4_C PF08743.10 KEZ39225.1 - 2.7e-35 120.5 0.1 5.9e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KEZ39225.1 - 7.6e-17 61.2 0.2 7.6e-17 61.2 0.2 2.2 2 1 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE ApoLp-III PF07464.11 KEZ39225.1 - 0.044 13.9 0.9 4.5 7.4 0.4 2.6 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DivIC PF04977.15 KEZ39225.1 - 0.056 13.2 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 Septum formation initiator tRNA-synt_2 PF00152.20 KEZ39226.1 - 3.4e-71 239.9 0.0 4.3e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Borrelia_P83 PF05262.11 KEZ39226.1 - 0.36 9.3 6.3 0.57 8.6 6.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.8 KEZ39226.1 - 1.1 8.1 7.1 1.4 7.7 7.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Fasciclin PF02469.22 KEZ39227.1 - 1.2e-44 151.7 0.0 2.3e-25 89.3 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Pal1 PF08316.11 KEZ39228.1 - 8.1e-43 146.5 1.6 2.7e-42 144.8 1.6 2.0 1 1 0 1 1 1 1 Pal1 cell morphology protein DUF3764 PF12594.8 KEZ39229.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) DUF3433 PF11915.8 KEZ39230.1 - 1e-33 115.7 11.2 8.6e-30 103.1 1.6 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Wzy_C PF04932.15 KEZ39230.1 - 0.01 15.5 7.3 2.3 7.8 0.0 2.9 2 1 0 2 2 2 0 O-Antigen ligase Atg14 PF10186.9 KEZ39232.1 - 5.9 5.9 17.2 0.097 11.7 5.4 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Raptor_N PF14538.6 KEZ39234.1 - 3.1e-64 215.4 0.0 5.9e-64 214.5 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KEZ39234.1 - 6.1e-07 30.0 1.8 14 6.8 0.0 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.6 KEZ39234.1 - 0.00016 22.0 0.6 0.069 13.5 0.0 4.0 4 0 0 4 4 4 1 HEAT repeats BBS2_Mid PF14783.6 KEZ39234.1 - 0.00031 20.7 0.0 1.4 9.0 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 KEZ39234.1 - 0.0039 17.3 4.8 3.1 8.3 0.2 5.1 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 KEZ39234.1 - 0.031 14.3 0.1 0.59 10.2 0.0 2.7 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 eIF3_p135 PF12807.7 KEZ39234.1 - 0.081 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Kelch_4 PF13418.6 KEZ39235.1 - 3.9e-38 129.2 8.3 2.2e-07 30.8 0.4 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KEZ39235.1 - 4.6e-28 96.5 4.4 1.9e-08 34.3 0.5 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KEZ39235.1 - 9.1e-28 96.0 7.0 6.4e-06 26.3 0.1 6.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KEZ39235.1 - 1.7e-27 94.9 11.3 1.9e-07 30.9 0.1 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_1 PF01344.25 KEZ39235.1 - 5e-27 93.2 4.7 5.3e-10 38.7 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KEZ39235.1 - 1e-17 63.3 7.9 3.4e-05 23.6 0.2 7.1 6 1 0 6 6 6 5 Kelch motif Pox_A_type_inc PF04508.12 KEZ39235.1 - 0.21 11.5 0.0 0.21 11.5 0.0 3.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat CFEM PF05730.11 KEZ39236.1 - 6.2e-05 23.0 1.8 6.2e-05 23.0 1.8 2.3 2 0 0 2 2 2 1 CFEM domain bVLRF1 PF18826.1 KEZ39237.1 - 1.4e-61 206.7 0.1 1.4e-61 206.7 0.1 1.9 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KEZ39237.1 - 1.4e-05 25.2 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KEZ39237.1 - 0.056 13.9 0.1 0.14 12.7 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeat HSP70 PF00012.20 KEZ39238.1 - 0.17 10.1 0.3 0.99 7.5 0.1 2.2 2 1 0 2 2 2 0 Hsp70 protein MscS_porin PF12795.7 KEZ39239.1 - 0.0018 17.8 7.8 0.0032 17.1 7.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Fez1 PF06818.15 KEZ39239.1 - 0.019 15.4 4.8 0.019 15.4 4.8 1.9 1 1 1 2 2 2 0 Fez1 Mod_r PF07200.13 KEZ39239.1 - 0.032 14.3 2.4 0.24 11.5 0.2 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein WDCP PF15390.6 KEZ39239.1 - 0.064 11.6 5.6 0.04 12.3 3.7 1.4 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF4763 PF15960.5 KEZ39239.1 - 0.094 12.0 4.9 0.18 11.1 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) WEMBL PF05701.11 KEZ39239.1 - 0.096 11.4 7.3 0.19 10.4 5.3 2.2 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Uds1 PF15456.6 KEZ39239.1 - 0.34 11.1 7.7 0.43 10.7 2.8 2.7 2 1 0 2 2 2 0 Up-regulated During Septation MPS2 PF17060.5 KEZ39239.1 - 0.63 9.2 5.7 0.39 9.9 3.4 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 ATG16 PF08614.11 KEZ39239.1 - 1.6 8.9 11.5 4.4 7.5 11.3 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 KEZ39239.1 - 1.7 8.7 7.3 2.6 8.1 0.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.9 KEZ39239.1 - 3.6 6.0 10.4 6.6 5.2 10.0 1.4 1 1 0 1 1 1 0 Macoilin family PTR2 PF00854.21 KEZ39240.1 - 1.3e-78 264.6 8.2 1.3e-78 264.6 6.0 1.9 1 1 1 2 2 2 1 POT family Hol_Tox PF16935.5 KEZ39240.1 - 0.57 10.3 2.1 0.83 9.7 0.7 2.0 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) Glyco_hydro_6 PF01341.17 KEZ39241.1 - 1e-100 337.4 0.0 1.3e-100 337.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 PI3_PI4_kinase PF00454.27 KEZ39242.1 - 1.1e-49 169.6 0.0 1.9e-49 168.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 KEZ39242.1 - 2.3e-32 110.9 1.1 8.2e-32 109.2 0.4 2.5 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 KEZ39242.1 - 1e-28 100.6 1.7 2e-28 99.6 1.7 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KEZ39242.1 - 2.7e-17 62.3 0.0 5.7e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 KEZ39242.1 - 0.041 14.4 1.0 3 8.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ39242.1 - 2.8 9.0 4.8 14 6.8 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-PARP PF00645.18 KEZ39243.1 - 2.9e-18 66.5 0.4 2.9e-18 66.5 0.4 2.7 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Antifungal_pept PF11410.8 KEZ39244.1 - 2.5 8.1 12.6 0.43 10.5 4.3 2.3 1 1 1 2 2 2 0 Antifungal peptide Med17 PF10156.9 KEZ39246.1 - 8.5e-77 258.8 0.0 1.1e-76 258.5 0.0 1.0 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PI-PLC-X PF00388.19 KEZ39247.1 - 1.1e-52 177.4 0.0 1.8e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEZ39247.1 - 8.5e-39 132.5 0.0 1.6e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain zf-C2H2 PF00096.26 KEZ39248.1 - 6.2e-07 29.5 17.8 0.00022 21.5 0.9 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KEZ39248.1 - 3.4e-06 27.1 10.3 3.4e-06 27.1 10.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KEZ39248.1 - 0.0015 18.9 3.0 0.0015 18.9 3.0 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KEZ39248.1 - 0.01 15.8 5.3 0.3 11.1 1.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KEZ39248.1 - 0.019 15.7 0.3 0.019 15.7 0.3 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger eIF-5a PF01287.20 KEZ39252.1 - 5.2e-07 29.7 0.1 8.5e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 KEZ39252.1 - 0.0058 17.3 12.0 0.017 15.8 1.6 2.6 1 1 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red ZapB PF06005.12 KEZ39253.1 - 0.0063 16.9 1.9 0.0063 16.9 1.9 3.6 4 0 0 4 4 4 1 Cell division protein ZapB Med21 PF11221.8 KEZ39253.1 - 0.03 14.6 0.1 0.03 14.6 0.1 5.4 7 0 0 7 7 7 0 Subunit 21 of Mediator complex Gon7 PF08738.10 KEZ39253.1 - 0.26 11.4 5.7 1.3 9.2 0.5 3.4 3 0 0 3 3 3 0 Gon7 family HCMV_UL139 PF12507.8 KEZ39253.1 - 0.84 10.0 3.2 11 6.4 0.0 3.0 3 0 0 3 3 3 0 Human Cytomegalovirus UL139 protein DivIC PF04977.15 KEZ39253.1 - 9.2 6.1 8.5 0.6 9.9 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator Myosin_head PF00063.21 KEZ39254.1 - 1.5e-269 895.9 0.0 6.6e-269 893.8 0.0 2.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KEZ39254.1 - 2.7e-12 46.3 0.4 9.2e-12 44.6 0.4 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KEZ39254.1 - 7.5e-10 37.3 46.0 7.5e-10 37.3 46.0 7.2 2 2 4 7 7 7 5 Myosin tail AAA_22 PF13401.6 KEZ39254.1 - 0.059 13.6 0.0 0.059 13.6 0.0 5.8 6 1 1 7 7 7 0 AAA domain DUF2442 PF10387.9 KEZ39254.1 - 0.11 12.8 0.0 0.72 10.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) UDPG_MGDP_dh_N PF03721.14 KEZ39254.1 - 0.41 10.2 2.7 1.1 8.8 2.7 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PHD PF00628.29 KEZ39256.1 - 1.4e-09 37.7 2.8 3.1e-09 36.6 2.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KEZ39256.1 - 0.0099 15.4 4.1 0.018 14.6 4.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KEZ39256.1 - 0.07 13.2 1.7 0.16 12.0 1.7 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger UIM PF02809.20 KEZ39256.1 - 0.39 10.8 7.0 0.042 13.8 1.8 2.3 3 0 0 3 3 3 0 Ubiquitin interaction motif CEBP_ZZ PF16366.5 KEZ39256.1 - 0.61 10.4 3.5 1.5 9.1 3.5 1.6 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DLH PF01738.18 KEZ39259.1 - 1.1e-15 57.8 0.0 1.3e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KEZ39259.1 - 0.0048 16.6 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ39259.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 1 1 2 2 2 0 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 KEZ39260.1 - 7.4e-50 169.7 0.0 9.2e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ39260.1 - 2.7e-33 115.1 3.4 2e-31 109.0 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEZ39260.1 - 5.9e-08 32.8 3.2 6e-07 29.5 0.0 2.1 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KEZ39260.1 - 0.098 12.0 0.0 0.69 9.3 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Acyl-CoA_dh_1 PF00441.24 KEZ39262.1 - 1.8e-42 145.1 0.8 3e-42 144.4 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ39262.1 - 2.6e-31 108.6 0.0 7.2e-31 107.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ39262.1 - 5.7e-27 93.8 0.1 1e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ39262.1 - 5.1e-14 52.7 0.1 9.1e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KEZ39262.1 - 2.2e-06 27.6 0.2 5e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 KEZ39263.1 - 1.1e-136 456.4 0.1 1.4e-136 456.1 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KEZ39263.1 - 0.007 15.9 0.1 0.44 10.0 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) DUF1348 PF07080.11 KEZ39264.1 - 2.9e-30 104.9 7.6 5.1e-24 84.6 2.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1348) Redoxin PF08534.10 KEZ39265.1 - 3.4e-34 117.7 0.0 3.8e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KEZ39265.1 - 3.3e-07 30.2 0.0 4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF295 PF03478.18 KEZ39265.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Ribosomal_L24e PF01246.20 KEZ39266.1 - 2.5e-28 98.1 0.2 5.4e-28 97.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Phosducin PF02114.16 KEZ39267.1 - 5.4e-15 55.1 0.1 8.8e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KEZ39267.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin LRR_8 PF13855.6 KEZ39268.1 - 4.4e-10 39.2 5.1 4.4e-10 39.2 5.1 3.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 KEZ39268.1 - 9.5e-09 35.4 12.8 8.4e-06 26.1 5.5 4.0 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEZ39268.1 - 4.5 8.2 19.7 0.71 10.6 2.1 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat EMC1_C PF07774.13 KEZ39269.1 - 2.2e-71 240.0 0.0 4.1e-71 239.0 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KEZ39269.1 - 3.2e-23 82.6 6.3 2.7e-19 69.7 1.7 2.6 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KEZ39269.1 - 6.7e-09 35.2 0.4 9.9e-05 22.1 0.0 5.6 6 0 0 6 6 6 1 PQQ enzyme repeat EST1_DNA_bind PF10373.9 KEZ39270.1 - 1.8e-10 40.8 0.1 4.9e-08 32.8 0.1 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain SQS_PSY PF00494.19 KEZ39270.1 - 0.01 15.3 0.6 0.028 13.9 0.2 1.9 2 0 0 2 2 2 0 Squalene/phytoene synthase DUF4288 PF14119.6 KEZ39270.1 - 0.063 13.7 0.5 0.21 12.0 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) ThiF PF00899.21 KEZ39271.1 - 3.9e-41 141.0 0.0 6.6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KEZ39271.1 - 0.0001 22.6 0.0 0.00031 21.0 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AAA_26 PF13500.6 KEZ39271.1 - 0.0083 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UDPG_MGDP_dh_N PF03721.14 KEZ39271.1 - 0.015 14.9 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Coatomer_E PF04733.14 KEZ39271.1 - 0.035 13.5 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Coatomer epsilon subunit Atg29_N PF18388.1 KEZ39275.1 - 2.4e-06 27.2 3.8 5.2e-06 26.2 3.8 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain RXT2_N PF08595.11 KEZ39277.1 - 0.14 12.1 12.3 0.3 11.1 12.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4820 PF16091.5 KEZ39277.1 - 0.73 9.2 4.8 1.3 8.4 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cwf_Cwc_15 PF04889.12 KEZ39277.1 - 1.2 8.8 22.6 0.1 12.3 18.0 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KEZ39277.1 - 5.4 5.1 24.2 8.1 4.5 24.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KEZ39277.1 - 6.5 4.9 17.6 9.6 4.4 17.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S8 PF00082.22 KEZ39278.1 - 7.8e-35 120.6 5.9 1.3e-34 119.8 5.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEZ39278.1 - 3.3e-19 69.3 0.4 6.9e-19 68.3 0.4 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cep57_MT_bd PF06657.13 KEZ39278.1 - 0.2 12.1 0.1 0.42 11.1 0.1 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Beach PF02138.18 KEZ39279.1 - 6.6e-120 399.6 0.0 1.1e-119 398.9 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KEZ39279.1 - 5.8e-10 39.2 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 KEZ39279.1 - 0.00027 20.3 0.2 0.00064 19.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 KEZ39279.1 - 0.082 13.8 0.2 73 4.5 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat p450 PF00067.22 KEZ39280.1 - 2.7e-52 178.1 0.0 3.3e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDOST_48kD PF03345.14 KEZ39281.1 - 8.4e-161 535.4 0.0 9.8e-161 535.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Isy1 PF06246.12 KEZ39282.1 - 1.7e-91 306.3 1.7 2e-91 306.1 1.7 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KEZ39282.1 - 0.0024 17.9 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 YolD-like protein Glyco_hydro_3_C PF01915.22 KEZ39283.1 - 2.4e-41 142.0 0.1 3.5e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ39283.1 - 1.5e-30 106.6 0.0 2.4e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ39283.1 - 6.2e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CALM_bind PF16025.5 KEZ39285.1 - 0.13 12.8 4.4 0.21 12.1 4.4 1.3 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding AhpC-TSA_2 PF13911.6 KEZ39286.1 - 3.2e-07 30.5 0.1 6.3e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KEZ39286.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Redoxin PAP_assoc PF03828.19 KEZ39287.1 - 1e-18 67.2 0.3 2.7e-18 65.9 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEZ39287.1 - 1.8e-05 25.0 0.0 3.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KEZ39287.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ANAPC_CDC26 PF10471.9 KEZ39287.1 - 5.4 7.9 20.1 0.53 11.2 5.8 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 TerB_C PF15615.6 KEZ39288.1 - 0.14 12.4 0.2 1.2 9.5 0.0 2.4 3 0 0 3 3 3 0 TerB-C domain eIF-1a PF01176.19 KEZ39289.1 - 9e-21 73.5 0.1 1.3e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 KEZ39290.1 - 1.2e-26 92.8 0.1 1.6e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KEZ39290.1 - 0.00077 19.2 0.4 0.0017 18.1 0.4 1.6 1 0 0 1 1 1 1 WH2 motif IBR PF01485.21 KEZ39292.1 - 8.7e-07 29.1 9.8 8.7e-07 29.1 9.8 2.9 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain MmgE_PrpD PF03972.14 KEZ39293.1 - 6.9e-148 492.8 0.0 8.4e-148 492.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family SH3_1 PF00018.28 KEZ39294.1 - 3e-15 55.5 0.1 4.6e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ39294.1 - 1.8e-09 37.3 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEZ39294.1 - 6.5e-08 32.1 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF910 PF06014.11 KEZ39294.1 - 0.031 14.3 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) HhH-GPD PF00730.25 KEZ39295.1 - 0.0055 17.1 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SEN1_N PF12726.7 KEZ39296.1 - 1.1e-176 589.3 0.6 1.6e-176 588.8 0.6 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KEZ39296.1 - 2.4e-69 234.1 0.5 2.4e-69 234.1 0.5 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KEZ39296.1 - 1.7e-62 210.6 0.1 8.5e-62 208.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEZ39296.1 - 2.5e-08 34.4 0.1 1.3e-07 32.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ39296.1 - 4.4e-08 33.1 0.2 0.00018 21.3 0.2 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ39296.1 - 6.9e-05 22.7 1.0 0.046 13.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KEZ39296.1 - 0.0054 16.3 0.1 0.0054 16.3 0.1 3.0 2 2 0 3 3 3 1 UvrD/REP helicase N-terminal domain kleA_kleC PF17383.2 KEZ39296.1 - 0.059 13.7 1.1 0.32 11.4 1.1 2.3 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Ribosomal_S27e PF01667.17 KEZ39297.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KEZ39297.1 - 0.13 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 KEZ39297.1 - 0.39 10.7 5.8 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type SIP1 PF04938.12 KEZ39298.1 - 1.8e-10 40.9 0.0 9.6e-09 35.3 0.0 2.7 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) FAD_binding_4 PF01565.23 KEZ39299.1 - 2e-25 89.1 2.6 4.1e-25 88.2 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEZ39299.1 - 7.1e-13 48.4 0.8 1.4e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like WD40 PF00400.32 KEZ39301.1 - 4e-11 43.3 6.9 0.012 16.5 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 KEZ39301.1 - 0.028 13.1 0.9 0.95 8.0 0.0 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KEZ39301.1 - 0.052 12.5 0.1 2.4 7.0 0.0 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PH_TFIIH PF08567.11 KEZ39301.1 - 0.091 13.1 0.1 0.27 11.6 0.1 1.8 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain PQQ_3 PF13570.6 KEZ39301.1 - 0.19 12.3 0.2 5.6 7.6 0.0 3.5 5 1 0 5 5 5 0 PQQ-like domain Pro-kuma_activ PF09286.11 KEZ39302.1 - 6.9e-45 152.8 0.1 2e-44 151.3 0.1 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KEZ39302.1 - 9.6e-08 31.6 0.5 1.5e-07 31.0 0.5 1.2 1 0 0 1 1 1 1 Subtilase family Complex1_LYR PF05347.15 KEZ39303.1 - 2.5e-23 81.9 2.9 3.2e-23 81.5 2.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEZ39303.1 - 4.8e-10 40.0 1.7 5.3e-10 39.9 1.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KEZ39303.1 - 0.0006 20.4 0.2 0.00074 20.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 KEZ39303.1 - 0.035 14.1 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Bac_luciferase PF00296.20 KEZ39303.1 - 0.061 12.7 0.1 0.083 12.3 0.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase SCIMP PF15050.6 KEZ39303.1 - 0.13 12.7 0.1 0.15 12.5 0.1 1.1 1 0 0 1 1 1 0 SCIMP protein OPT PF03169.15 KEZ39305.1 - 4.7e-185 616.8 52.4 5.4e-185 616.6 52.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2937 PF11157.8 KEZ39305.1 - 0.054 13.2 0.1 1.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) EIAV_GP90 PF00971.18 KEZ39305.1 - 3.3 6.3 5.8 8.2 5.0 0.1 2.4 3 0 0 3 3 3 0 EIAV coat protein, gp90 Pyridoxal_deC PF00282.19 KEZ39306.1 - 1e-61 208.8 0.0 1.5e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MFS_1 PF07690.16 KEZ39306.1 - 9.4e-42 143.2 35.3 3.6e-40 138.0 18.7 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39306.1 - 5.9e-09 35.3 0.5 5.9e-09 35.3 0.5 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter Podoplanin PF05808.11 KEZ39306.1 - 0.0015 18.7 0.1 0.0038 17.4 0.1 1.6 1 0 0 1 1 1 1 Podoplanin TRI12 PF06609.13 KEZ39306.1 - 0.0018 16.8 0.4 0.003 16.0 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Aminotran_5 PF00266.19 KEZ39306.1 - 0.0019 17.2 0.0 0.0038 16.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Sporozoite_P67 PF05642.11 KEZ39306.1 - 0.013 13.6 4.1 0.019 13.1 4.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LapA_dom PF06305.11 KEZ39306.1 - 0.27 11.1 0.8 1.6 8.6 0.8 2.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Apt1 PF10351.9 KEZ39306.1 - 0.82 8.4 2.4 1.3 7.8 2.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KEZ39306.1 - 2.9 6.3 5.0 4.7 5.7 5.0 1.2 1 0 0 1 1 1 0 Macoilin family Acatn PF13000.7 KEZ39307.1 - 2.7e-163 544.4 18.2 1.1e-81 275.0 7.9 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 KEZ39308.1 - 6.1e-67 225.7 0.3 3.7e-66 223.1 0.0 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF3999 PF13163.6 KEZ39308.1 - 0.0058 15.9 0.2 0.012 14.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3999) Glyco_H_20C_C PF18088.1 KEZ39308.1 - 0.83 9.5 6.0 0.15 11.9 0.3 2.2 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain MFS_1 PF07690.16 KEZ39309.1 - 1.1e-35 123.3 44.9 1.1e-35 123.3 44.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39309.1 - 2.7e-08 33.1 36.8 8.1e-05 21.7 13.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Wbp11 PF09429.10 KEZ39310.1 - 3.9e-21 75.2 10.1 3.9e-21 75.2 10.1 2.3 3 0 0 3 3 3 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 KEZ39310.1 - 0.011 15.0 0.7 0.017 14.5 0.7 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Pkinase PF00069.25 KEZ39311.1 - 3e-60 203.8 0.0 2.7e-59 200.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39311.1 - 1.4e-28 99.9 0.4 4e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KEZ39311.1 - 0.0011 19.6 0.9 0.0011 19.6 0.9 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KEZ39311.1 - 0.0037 16.6 0.3 0.017 14.5 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KEZ39311.1 - 0.0062 16.5 0.1 0.095 12.6 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KEZ39311.1 - 0.024 14.0 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEZ39311.1 - 0.029 13.3 0.0 0.069 12.1 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain DUF4423 PF14394.6 KEZ39312.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Ank_2 PF12796.7 KEZ39313.1 - 6.6e-101 331.1 0.2 3.1e-17 62.9 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ39313.1 - 1.8e-62 206.9 0.5 3.8e-11 43.3 0.0 7.9 3 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KEZ39313.1 - 9.2e-62 203.0 0.0 0.00024 21.4 0.0 11.7 11 0 0 11 11 11 11 Ankyrin repeat Ank_3 PF13606.6 KEZ39313.1 - 4.5e-57 183.3 0.0 0.0026 18.1 0.0 12.4 13 0 0 13 13 11 11 Ankyrin repeat Ank_5 PF13857.6 KEZ39313.1 - 1.3e-38 130.5 1.7 3.5e-07 30.4 0.0 8.3 2 2 6 9 9 9 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KEZ39313.1 - 9.2e-12 44.7 0.0 3.7e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KEZ39313.1 - 4.6e-08 33.1 0.0 9.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ39313.1 - 0.00014 22.3 0.1 0.00046 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KEZ39313.1 - 0.002 17.8 0.0 0.066 13.0 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ39313.1 - 0.0056 16.9 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KEZ39313.1 - 0.0069 16.9 0.0 0.057 13.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter PEGA PF08308.11 KEZ39313.1 - 0.0081 16.0 1.3 98 3.0 0.0 5.6 5 1 0 5 5 5 0 PEGA domain Cthe_2159 PF14262.6 KEZ39313.1 - 0.011 15.1 0.0 18 4.6 0.0 4.0 1 1 2 3 3 3 0 Carbohydrate-binding domain-containing protein Cthe_2159 KAP_NTPase PF07693.14 KEZ39313.1 - 0.015 14.6 0.1 0.35 10.0 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 KEZ39313.1 - 0.1 13.1 0.0 0.45 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Nse4-Nse3_bdg PF15412.6 KEZ39313.1 - 0.16 12.1 19.5 76 3.5 0.0 9.4 11 0 0 11 11 11 0 Binding domain of Nse4/EID3 to Nse3-MAGE GATA PF00320.27 KEZ39315.1 - 1.9e-16 59.3 2.3 3.6e-16 58.5 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KEZ39315.1 - 7.8e-10 38.4 0.3 1.7e-09 37.4 0.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ipi1_N PF12333.8 KEZ39317.1 - 8.7e-26 90.5 0.1 8.7e-26 90.5 0.1 2.4 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation DEAD PF00270.29 KEZ39318.1 - 8.7e-43 146.1 0.0 1.3e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ39318.1 - 1.6e-26 92.8 0.0 1.2e-25 90.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEZ39318.1 - 0.03 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Aldedh PF00171.22 KEZ39319.1 - 1.5e-111 373.2 0.0 2.1e-111 372.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoLip_ATPase_C PF16212.5 KEZ39320.1 - 6.6e-80 268.5 28.9 6.6e-80 268.5 28.9 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 KEZ39320.1 - 1.2e-13 50.9 0.0 5.3e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ39320.1 - 5.4e-13 49.7 2.8 0.00095 19.5 0.1 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEZ39320.1 - 0.002 17.7 0.0 0.012 15.2 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEZ39320.1 - 0.014 15.1 0.4 0.033 13.9 0.4 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.18 KEZ39322.1 - 5e-57 192.5 7.8 5.7e-57 192.4 7.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Ntox50 PF15542.6 KEZ39322.1 - 0.1 13.4 1.6 0.17 12.7 0.7 1.8 1 1 1 2 2 2 0 Bacterial toxin 50 Cas_GSU0053 PF09617.10 KEZ39322.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Mg_trans_NIPA PF05653.14 KEZ39323.1 - 6.8e-15 54.9 13.4 1.7e-14 53.6 13.4 1.5 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KEZ39323.1 - 6.4e-06 26.4 15.9 0.00015 22.0 0.0 2.8 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 KEZ39323.1 - 0.0017 17.6 4.0 0.0017 17.6 4.0 2.6 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport COX4_pro_2 PF07835.12 KEZ39323.1 - 0.38 10.9 3.0 0.26 11.4 0.2 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Multi_Drug_Res PF00893.19 KEZ39323.1 - 1.2 9.8 8.7 10 6.8 3.1 2.8 2 1 0 2 2 2 0 Small Multidrug Resistance protein DUF4191 PF13829.6 KEZ39324.1 - 0.14 11.5 0.4 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Tetraspanin PF00335.20 KEZ39324.1 - 2 8.0 12.6 6.4 6.4 12.6 2.1 1 1 0 1 1 1 0 Tetraspanin family SRF-TF PF00319.18 KEZ39325.1 - 4.5e-21 74.1 0.1 6.3e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PGA2 PF07543.12 KEZ39325.1 - 0.053 13.5 2.2 0.09 12.8 2.2 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Ctr PF04145.15 KEZ39326.1 - 5.1e-29 101.8 0.3 6.6e-29 101.4 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Proton_antipo_N PF00662.20 KEZ39326.1 - 0.032 14.3 0.2 0.071 13.2 0.2 1.7 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Malate_synthase PF01274.22 KEZ39327.1 - 1.4e-228 759.5 0.0 1.5e-228 759.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 KEZ39327.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Pkinase PF00069.25 KEZ39328.1 - 1.5e-65 221.2 0.0 9.2e-65 218.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39328.1 - 7.7e-36 123.7 0.0 2.5e-34 118.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 KEZ39328.1 - 2.8e-27 94.8 0.0 5e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KEZ39328.1 - 1.8e-06 27.5 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEZ39328.1 - 0.0027 16.7 0.1 0.0044 16.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 KEZ39328.1 - 0.01 15.4 0.1 0.029 14.0 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KEZ39328.1 - 0.024 14.0 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ39328.1 - 0.028 14.3 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family SMC_N PF02463.19 KEZ39329.1 - 3.8e-26 91.9 0.0 6.6e-26 91.1 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEZ39329.1 - 1.3e-11 45.4 40.4 1.2e-10 42.2 17.8 4.6 3 1 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KEZ39329.1 - 2.7e-07 30.7 0.5 0.00019 21.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KEZ39329.1 - 0.0017 18.8 0.0 0.0078 16.6 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEZ39329.1 - 0.0018 18.0 0.0 0.0053 16.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ39329.1 - 0.0025 17.7 0.1 0.072 13.0 0.0 3.0 3 1 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 KEZ39329.1 - 0.041 13.6 15.5 0.013 15.3 5.0 3.7 2 2 0 2 2 2 0 AAA ATPase domain DUF2680 PF10925.8 KEZ39329.1 - 0.068 13.2 4.2 2.8 8.0 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) MMR_HSR1 PF01926.23 KEZ39329.1 - 0.14 12.2 0.0 0.72 9.9 0.0 2.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Imm7 PF15585.6 KEZ39329.1 - 0.41 10.9 2.0 14 5.9 0.7 3.3 3 0 0 3 3 3 0 Immunity protein 7 COG5 PF10392.9 KEZ39329.1 - 0.9 9.7 11.6 6.8 6.9 0.1 4.5 4 0 0 4 4 4 0 Golgi transport complex subunit 5 AAA_22 PF13401.6 KEZ39329.1 - 0.92 9.8 4.0 0.95 9.7 0.0 3.1 3 1 0 3 3 2 0 AAA domain Baculo_PEP_C PF04513.12 KEZ39329.1 - 3.8 7.5 18.3 0.85 9.7 1.2 5.1 6 1 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApbA_C PF08546.11 KEZ39330.1 - 2.7e-25 89.0 0.0 4.3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KEZ39330.1 - 1.9e-20 73.1 0.0 2.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AGH PF17558.2 KEZ39330.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Androgenic gland hormone DASH_Hsk3 PF08227.11 KEZ39331.1 - 1e-20 73.8 5.0 1e-20 73.8 5.0 1.6 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 KEZ39331.1 - 0.085 11.6 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DEAD PF00270.29 KEZ39332.1 - 1.4e-39 135.7 0.1 2.3e-39 135.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ39332.1 - 5e-25 88.0 0.3 1.2e-23 83.5 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ39332.1 - 2.3e-07 31.0 0.0 5.4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KEZ39332.1 - 0.037 14.6 0.6 0.086 13.4 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) Cyclin PF08613.11 KEZ39333.1 - 1.6e-05 25.3 0.8 2.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KEZ39333.1 - 0.0011 18.7 0.1 0.0028 17.4 0.1 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain F-box-like PF12937.7 KEZ39334.1 - 0.11 12.3 0.4 0.21 11.5 0.4 1.4 1 0 0 1 1 1 0 F-box-like CorA PF01544.18 KEZ39335.1 - 9.8e-15 54.6 0.1 1.4e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ERCC4 PF02732.15 KEZ39337.1 - 5.1e-19 69.0 0.0 1.1e-18 68.0 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain YjeF_N PF03853.15 KEZ39338.1 - 6e-23 81.6 0.0 9.2e-23 81.0 0.0 1.3 1 1 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.19 KEZ39339.1 - 2.8e-26 91.3 0.1 3.8e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.18 KEZ39340.1 - 3.9e-86 289.3 18.9 6.9e-86 288.5 18.9 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KEZ39340.1 - 3.8e-05 22.9 22.1 3.8e-05 22.9 22.1 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Abhydrolase_9_N PF15420.6 KEZ39340.1 - 0.91 9.5 13.8 0.025 14.6 3.4 3.0 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Dynactin_p22 PF07426.11 KEZ39341.1 - 3.5e-11 43.2 0.0 6.4e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Dynactin subunit p22 Gal4_dimer PF03902.13 KEZ39341.1 - 0.39 10.9 2.4 25 5.1 0.0 2.7 2 0 0 2 2 2 0 Gal4-like dimerisation domain SH3_1 PF00018.28 KEZ39342.1 - 2.5e-09 36.6 0.1 4.1e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ39342.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEZ39342.1 - 4.3e-06 26.3 0.0 7.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DASH_Spc19 PF08287.11 KEZ39343.1 - 7.8e-48 162.3 0.2 1e-47 161.9 0.2 1.2 1 0 0 1 1 1 1 Spc19 LIAS_N PF16881.5 KEZ39344.1 - 3.1e-17 62.9 0.0 8.2e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KEZ39344.1 - 7.1e-14 52.5 0.2 1.2e-13 51.8 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF241 PF03087.14 KEZ39344.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Pectate_lyase_3 PF12708.7 KEZ39345.1 - 1.6e-92 309.2 3.5 8.1e-81 271.0 0.2 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KEZ39345.1 - 0.00044 19.9 2.1 0.04 13.6 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Methyltrn_RNA_3 PF02598.17 KEZ39346.1 - 1.1e-97 327.1 0.0 1.4e-97 326.7 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Rsm22 PF09243.10 KEZ39347.1 - 1.1e-31 110.2 0.0 3.6e-31 108.4 0.0 1.9 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Thioredoxin PF00085.20 KEZ39347.1 - 7.1e-25 87.0 0.0 1.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Methyltransf_23 PF13489.6 KEZ39347.1 - 9.3e-05 22.3 0.0 0.00038 20.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Thioredoxin_2 PF13098.6 KEZ39347.1 - 0.00014 22.3 0.0 0.00048 20.6 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KEZ39347.1 - 0.00063 19.5 0.1 0.0034 17.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 KEZ39347.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KEZ39347.1 - 0.0022 17.9 0.0 0.0058 16.5 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KEZ39347.1 - 0.0077 16.5 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KEZ39347.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Methyltransf_12 PF08242.12 KEZ39347.1 - 0.04 14.7 0.0 0.099 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39347.1 - 0.18 12.5 0.0 0.58 10.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain QRPTase_C PF01729.19 KEZ39348.1 - 3.4e-54 183.1 0.0 4e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KEZ39348.1 - 5.1e-17 61.7 0.1 6.7e-16 58.1 0.0 2.7 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain B12-binding PF02310.19 KEZ39348.1 - 0.12 12.4 0.2 0.21 11.6 0.2 1.3 1 0 0 1 1 1 0 B12 binding domain FHA PF00498.26 KEZ39349.1 - 1.3e-16 60.6 0.0 3.8e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 FHA domain GAS PF13851.6 KEZ39349.1 - 1.9e-06 27.4 12.1 0.001 18.4 1.9 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding CCDC154 PF15450.6 KEZ39349.1 - 5.8e-05 21.8 4.5 5.8e-05 21.8 4.5 2.1 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 154 Yop-YscD_cpl PF16697.5 KEZ39349.1 - 0.00029 21.1 0.0 0.001 19.3 0.0 2.0 2 0 0 2 2 1 1 Inner membrane component of T3SS, cytoplasmic domain FAM76 PF16046.5 KEZ39349.1 - 0.0011 18.5 4.7 0.0048 16.3 0.3 2.5 2 0 0 2 2 2 1 FAM76 protein DUF4201 PF13870.6 KEZ39349.1 - 0.03 14.1 12.1 0.52 10.0 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) YhfZ_C PF14503.6 KEZ39349.1 - 0.062 12.8 2.5 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 YhfZ C-terminal domain Cnn_1N PF07989.11 KEZ39349.1 - 0.1 12.8 7.2 2.5 8.3 0.1 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Med9 PF07544.13 KEZ39349.1 - 0.11 12.6 6.8 0.42 10.7 1.2 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Laminin_II PF06009.12 KEZ39349.1 - 0.14 12.1 15.6 1.3 9.1 5.3 2.4 2 0 0 2 2 2 0 Laminin Domain II HHV-5_US34A PF17087.5 KEZ39349.1 - 0.46 10.7 1.6 1.3 9.2 1.6 1.7 1 0 0 1 1 1 0 Herpesvirus US34A protein family ATG16 PF08614.11 KEZ39349.1 - 0.7 10.1 31.8 0.085 13.1 10.5 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KEZ39349.1 - 1.2 9.2 8.0 4.5 7.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) betaPIX_CC PF16523.5 KEZ39349.1 - 1.9 8.3 9.5 2.9 7.8 0.9 2.6 2 0 0 2 2 2 0 betaPIX coiled coil FH2 PF02181.23 KEZ39349.1 - 2 7.4 9.8 5.5 6.0 1.8 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain Fez1 PF06818.15 KEZ39349.1 - 2.1 8.8 24.1 0.4 11.1 18.9 2.1 1 1 1 2 2 2 0 Fez1 COG2 PF06148.11 KEZ39349.1 - 6.2 6.9 12.8 1.4 9.0 1.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Romo1 PF10247.9 KEZ39350.1 - 4.7e-27 94.2 15.6 6.5e-27 93.7 15.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KEZ39350.1 - 0.038 14.3 6.3 0.056 13.8 6.3 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.6 KEZ39350.1 - 2.7 7.8 9.5 2.4 8.0 3.6 2.3 2 0 0 2 2 2 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 KEZ39350.1 - 7.1 6.5 9.0 4.5 7.1 1.5 1.9 1 1 1 2 2 2 0 YMGG-like Gly-zipper SIR2 PF02146.17 KEZ39351.1 - 4e-54 183.2 0.0 5.8e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KEZ39351.1 - 0.052 13.3 0.0 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain GMC_oxred_N PF00732.19 KEZ39352.1 - 1e-44 153.1 0.0 1.3e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39352.1 - 5.2e-23 82.2 0.0 1.2e-22 81.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ39352.1 - 8.4e-06 25.1 0.3 0.00023 20.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEZ39352.1 - 0.0014 17.9 0.1 0.0023 17.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 KEZ39352.1 - 0.034 14.4 0.2 0.24 11.7 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.6 KEZ39352.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ39352.1 - 0.087 12.0 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ39352.1 - 0.15 11.6 3.6 0.82 9.2 2.5 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ39352.1 - 0.17 10.9 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4880 PF16220.5 KEZ39352.1 - 1.5 8.8 4.1 42 4.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) Carb_anhydrase PF00194.21 KEZ39353.1 - 2.3e-31 109.3 0.0 3.1e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase NAT PF04768.13 KEZ39354.1 - 2.8e-37 128.0 0.0 7.7e-37 126.6 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KEZ39354.1 - 1.6e-30 106.0 0.0 4.9e-30 104.4 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KEZ39354.1 - 2.7e-27 95.9 0.0 5.1e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 KEZ39354.1 - 0.096 12.8 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.21 KEZ39355.1 - 8.6e-34 115.2 1.4 9.8e-34 115.0 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 KEZ39355.1 - 0.026 15.2 0.1 0.053 14.2 0.1 1.5 1 1 0 1 1 1 0 AT-hook-containing transcription factor MCU PF04678.13 KEZ39355.1 - 0.064 13.4 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Syntaxin_2 PF14523.6 KEZ39355.1 - 0.086 13.2 0.2 0.1 13.0 0.2 1.1 1 0 0 1 1 1 0 Syntaxin-like protein Glyco_hydro_76 PF03663.14 KEZ39356.1 - 5.9e-156 519.6 22.2 7e-156 519.3 22.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.22 KEZ39357.1 - 1.5e-34 119.6 0.0 1.7e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S14 PF00253.21 KEZ39358.1 - 2.6e-22 78.3 3.3 2.6e-22 78.3 0.8 1.9 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DHHC PF01529.20 KEZ39359.1 - 1.9e-34 118.6 8.8 1.9e-34 118.6 8.8 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 KEZ39359.1 - 6.9e-05 22.6 2.8 0.00028 20.6 0.2 2.1 2 0 0 2 2 2 1 Yip1 domain TYW3 PF02676.14 KEZ39361.1 - 7.7e-73 244.4 0.0 1e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.11 KEZ39362.1 - 4.9e-41 140.4 1.6 5.7e-41 140.2 1.6 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lebercilin PF15619.6 KEZ39362.1 - 8.7e-05 22.3 8.2 0.00011 22.0 8.2 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease APH PF01636.23 KEZ39363.1 - 2.5e-16 60.3 0.0 8.3e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KEZ39363.1 - 0.0052 15.7 0.0 0.022 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 KEZ39363.1 - 0.0065 15.9 0.0 0.018 14.4 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain EcKinase PF02958.20 KEZ39363.1 - 0.0065 15.8 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KEZ39363.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase HEAT PF02985.22 KEZ39364.1 - 2.8e-12 45.8 14.0 0.11 12.8 0.0 10.3 13 0 0 13 13 10 3 HEAT repeat HEAT_EZ PF13513.6 KEZ39364.1 - 4.8e-12 46.1 10.8 1e-08 35.5 0.0 7.8 8 1 1 9 9 9 1 HEAT-like repeat IBN_N PF03810.19 KEZ39364.1 - 2.8e-07 30.3 0.8 2.8e-07 30.3 0.8 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KEZ39364.1 - 2e-05 24.9 14.8 1.7 9.1 0.1 7.5 3 2 3 7 7 7 2 HEAT repeats Cnd1 PF12717.7 KEZ39364.1 - 8.1e-05 22.7 1.4 0.0027 17.7 0.1 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KEZ39364.1 - 0.007 16.0 4.7 6.8 6.2 0.1 5.6 4 2 3 8 8 8 1 CLASP N terminal NUC173 PF08161.12 KEZ39364.1 - 0.013 15.2 1.2 18 4.9 0.0 4.5 5 1 0 5 5 5 0 NUC173 domain DUF1548 PF07579.11 KEZ39364.1 - 0.034 14.5 0.3 0.7 10.2 0.0 3.0 3 1 1 4 4 4 0 Domain of Unknown Function (DUF1548) CTD_bind PF04818.13 KEZ39364.1 - 0.11 13.3 0.0 8.6 7.3 0.0 3.9 2 1 0 2 2 2 0 RNA polymerase II-binding domain. DUF3347 PF11827.8 KEZ39364.1 - 0.15 12.2 1.4 0.29 11.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Arm PF00514.23 KEZ39364.1 - 0.45 10.6 5.7 49 4.2 0.0 5.4 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Lipase_GDSL PF00657.22 KEZ39367.1 - 5.4e-13 49.4 0.5 8.1e-13 48.8 0.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KEZ39367.1 - 1.5e-12 48.3 2.5 1.5e-12 48.3 2.5 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 KEZ39367.1 - 0.079 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal zf-C2H2 PF00096.26 KEZ39368.1 - 1.3e-08 34.8 12.4 0.00056 20.2 2.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ39368.1 - 7.2e-05 23.0 2.6 7.2e-05 23.0 2.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ39368.1 - 0.012 16.3 17.4 0.12 13.2 2.6 2.9 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEZ39368.1 - 0.012 15.5 0.9 0.012 15.5 0.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ39368.1 - 0.093 13.1 0.4 0.093 13.1 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PAT1 PF09770.9 KEZ39368.1 - 0.13 10.5 14.6 0.14 10.4 14.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med3 PF11593.8 KEZ39368.1 - 0.29 10.3 24.5 0.43 9.7 24.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1387 PF07139.11 KEZ39368.1 - 0.68 9.6 8.0 1.3 8.7 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) zf-met PF12874.7 KEZ39368.1 - 0.81 10.2 8.8 0.087 13.2 1.6 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rpr2 PF04032.16 KEZ39368.1 - 1.1 9.5 6.5 0.61 10.4 0.5 2.4 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Presenilin PF01080.17 KEZ39368.1 - 5.2 5.7 9.8 7.4 5.2 9.8 1.1 1 0 0 1 1 1 0 Presenilin DUF2457 PF10446.9 KEZ39368.1 - 6.6 5.8 12.4 11 5.0 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Spt20 PF12090.8 KEZ39368.1 - 8.5 5.9 30.0 15 5.1 30.0 1.3 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 KEZ39369.1 - 3.3e-53 180.8 0.8 5.5e-34 117.7 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39369.1 - 1e-34 120.0 0.0 1.3e-33 116.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ39369.1 - 0.00025 20.5 0.0 0.0007 19.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like BTB PF00651.31 KEZ39370.1 - 1e-24 86.9 2.0 2.5e-12 47.0 1.6 3.0 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KEZ39370.1 - 4.5e-08 33.5 0.0 1.2e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ39370.1 - 2.1e-07 31.5 0.0 5.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ39370.1 - 2e-05 24.8 0.0 6.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ39370.1 - 4.9e-05 23.4 0.2 0.21 12.3 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KEZ39370.1 - 0.00015 22.1 0.1 0.015 15.8 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat DNA_gyraseB_C PF00986.21 KEZ39370.1 - 0.047 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus SCO1-SenC PF02630.14 KEZ39371.1 - 4.7e-49 165.7 0.0 6.6e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KEZ39371.1 - 0.00062 19.7 0.0 0.0018 18.2 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ39371.1 - 0.0049 16.6 0.0 0.049 13.3 0.0 2.1 1 1 0 1 1 1 1 Redoxin UPF0061 PF02696.14 KEZ39371.1 - 0.0099 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Hydrolase_6 PF13344.6 KEZ39372.1 - 3.4e-26 91.3 0.0 5.8e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ39372.1 - 9.6e-17 60.8 0.0 2.7e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEZ39372.1 - 0.00053 20.3 0.3 5 7.4 0.0 4.1 2 1 2 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEZ39372.1 - 0.17 11.9 0.0 23 5.0 0.0 3.2 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 KEZ39373.1 - 1.1e-51 175.5 0.0 1.2e-50 172.1 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase Rad21_Rec8_N PF04825.13 KEZ39373.1 - 1.5e-19 70.2 0.0 3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Choline_kin_N PF04428.14 KEZ39373.1 - 2.1e-17 62.5 0.0 4.3e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus Rad21_Rec8 PF04824.16 KEZ39373.1 - 3.5e-06 26.2 0.3 8.9e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein APH PF01636.23 KEZ39373.1 - 8.4e-05 22.6 0.8 0.00041 20.4 0.8 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family GDI PF00996.18 KEZ39374.1 - 7.8e-25 87.3 0.0 2.5e-24 85.6 0.0 1.7 1 1 0 1 1 1 1 GDP dissociation inhibitor MoaE PF02391.17 KEZ39375.1 - 7.6e-37 126.1 0.1 1.4e-36 125.2 0.1 1.5 1 0 0 1 1 1 1 MoaE protein Helo_like_N PF17111.5 KEZ39375.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins G-patch PF01585.23 KEZ39376.1 - 1.2e-10 41.0 2.1 2.7e-10 40.0 2.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KEZ39376.1 - 3.7e-06 26.9 1.2 1.2e-05 25.3 1.2 2.0 1 0 0 1 1 1 1 G-patch domain RED_N PF07808.13 KEZ39376.1 - 0.00085 19.0 1.5 0.00085 19.0 1.5 1.7 2 0 0 2 2 2 1 RED-like protein N-terminal region RRM_1 PF00076.22 KEZ39376.1 - 0.0014 18.4 0.0 0.079 12.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 KEZ39376.1 - 0.027 14.8 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEZ39376.1 - 0.12 12.6 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SET PF00856.28 KEZ39377.1 - 6.6e-13 49.4 0.2 4.4e-12 46.7 0.2 2.0 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 KEZ39377.1 - 0.3 11.4 1.8 3.3 8.1 0.9 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat RTC_insert PF05189.13 KEZ39378.1 - 0.084 13.4 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain ATP-synt_C PF00137.21 KEZ39379.1 - 3.4e-29 101.0 32.5 2e-18 66.5 9.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Bax1-I PF01027.20 KEZ39379.1 - 0.099 12.5 9.2 0.22 11.3 9.3 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 CNH PF00780.22 KEZ39380.1 - 2.3e-76 257.1 0.0 8e-76 255.3 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KEZ39380.1 - 1.3e-44 151.6 0.0 2.8e-44 150.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KEZ39380.1 - 4.5e-37 128.0 0.1 7.8e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KEZ39380.1 - 2.2e-16 59.7 0.0 4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Thioredox_DsbH PF03190.15 KEZ39381.1 - 1.3e-58 197.5 0.0 2.2e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KEZ39381.1 - 3.6e-07 30.3 0.0 7.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.14 KEZ39381.1 - 0.019 14.5 2.1 0.12 11.8 0.4 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 DLIC PF05783.11 KEZ39382.1 - 3.4e-33 115.2 0.0 2.5e-31 109.0 0.0 2.5 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 KEZ39383.1 - 2.2e-13 49.8 0.0 5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ39383.1 - 0.02 15.0 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif WD40 PF00400.32 KEZ39384.1 - 1.7e-07 31.8 0.1 0.027 15.3 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39384.1 - 2e-05 24.8 0.0 0.0041 17.4 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KEZ39384.1 - 0.00012 20.3 0.0 0.00048 18.3 0.0 1.9 2 1 1 3 3 3 1 IKI3 family Ge1_WD40 PF16529.5 KEZ39384.1 - 0.042 12.8 0.1 0.49 9.3 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KEZ39384.1 - 0.078 12.3 0.0 0.74 9.1 0.0 2.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.18 KEZ39385.1 - 2.6e-109 364.9 0.1 5.4e-109 363.8 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KEZ39385.1 - 5.5e-05 23.2 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEZ39385.1 - 0.012 15.7 3.0 2.1 8.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family GTP_EFTU PF00009.27 KEZ39385.1 - 0.023 14.2 1.3 0.071 12.6 0.1 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KEZ39385.1 - 0.055 13.8 0.9 0.19 12.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KEZ39385.1 - 0.057 13.3 0.4 0.057 13.3 0.4 2.4 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KEZ39385.1 - 0.085 13.3 5.5 5.5 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain EB1 PF03271.17 KEZ39385.1 - 0.11 12.8 0.6 5.5 7.3 1.1 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif Roc PF08477.13 KEZ39385.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_S17e PF00833.18 KEZ39385.1 - 0.62 10.0 3.9 1.3 8.9 3.9 1.5 1 0 0 1 1 1 0 Ribosomal S17 Bax1-I PF01027.20 KEZ39386.1 - 8.6e-51 172.7 27.8 1e-50 172.5 27.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF417 PF04224.12 KEZ39386.1 - 0.039 13.5 0.4 0.039 13.5 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF417 DsbD_2 PF13386.6 KEZ39386.1 - 0.5 10.3 9.9 0.85 9.5 9.6 1.5 1 1 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF1772 PF08592.11 KEZ39386.1 - 8.6 6.7 16.3 7.5 6.9 2.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) NUDE_C PF04880.13 KEZ39387.1 - 7.7 7.0 10.3 1.1 9.7 1.4 2.2 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region TRAM_LAG1_CLN8 PF03798.16 KEZ39388.1 - 6.8e-50 169.6 17.0 1.1e-49 168.9 17.0 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KEZ39388.1 - 1.2e-19 69.7 0.2 1.2e-19 69.7 0.2 2.5 2 0 0 2 2 2 1 TRAM1-like protein Gly_transf_sug PF04488.15 KEZ39389.1 - 9.1e-15 55.1 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif UBA_e1_thiolCys PF10585.9 KEZ39389.1 - 0.071 13.0 0.5 0.14 12.1 0.5 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Cu_amine_oxid PF01179.20 KEZ39390.1 - 1.5e-143 478.6 0.0 1.8e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KEZ39390.1 - 1.4e-05 25.2 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KEZ39390.1 - 0.026 14.9 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain NUDIX PF00293.28 KEZ39392.1 - 5.8e-08 32.9 0.0 9.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PP-binding PF00550.25 KEZ39392.1 - 0.0076 16.6 0.1 4.3 7.8 0.0 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site NUDIX PF00293.28 KEZ39393.1 - 2.6e-14 53.4 0.0 4.6e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.23 KEZ39394.1 - 4.1e-17 62.2 0.2 4.1e-17 62.2 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEZ39394.1 - 3.2e-06 27.5 0.1 7.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KEZ39394.1 - 0.05 13.6 0.3 0.12 12.4 0.0 1.8 2 1 0 2 2 2 0 Bromodomain associated Glutaredoxin PF00462.24 KEZ39394.1 - 0.16 12.2 0.7 1.8 8.8 0.1 2.1 1 1 1 2 2 2 0 Glutaredoxin adh_short PF00106.25 KEZ39395.1 - 1.8e-27 96.1 0.2 1.5e-22 80.0 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ39395.1 - 7e-19 68.3 0.0 1.7e-18 67.0 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase APH PF01636.23 KEZ39396.1 - 1.4e-09 38.3 0.1 2.6e-08 34.1 0.1 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family HNH_2 PF13391.6 KEZ39396.1 - 1.6e-09 37.8 0.0 5.2e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease COX16 PF14138.6 KEZ39397.1 - 1.2e-29 102.6 0.2 1.6e-29 102.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 KEZ39397.1 - 0.1 13.1 0.8 0.22 12.1 0.1 1.8 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Ribosomal_L24e PF01246.20 KEZ39397.1 - 0.28 11.4 2.0 0.31 11.3 0.6 1.8 2 1 0 2 2 2 0 Ribosomal protein L24e Amidase PF01425.21 KEZ39398.1 - 8.5e-103 344.7 0.1 1.8e-102 343.7 0.1 1.5 1 1 0 1 1 1 1 Amidase RNase_II_C_S1 PF18614.1 KEZ39398.1 - 0.26 11.3 1.5 0.89 9.6 0.1 2.5 3 0 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain Metallophos PF00149.28 KEZ39399.1 - 6e-10 40.0 2.4 6e-10 40.0 2.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KEZ39399.1 - 0.069 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain PCI PF01399.27 KEZ39400.1 - 7.5e-23 81.0 0.0 3.5e-22 78.9 0.0 2.2 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 KEZ39400.1 - 3.8e-16 58.9 2.3 9.9e-16 57.5 2.3 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Calcipressin PF04847.12 KEZ39400.1 - 0.4 10.4 2.0 0.73 9.5 0.1 2.2 2 0 0 2 2 2 0 Calcipressin FSH1 PF03959.13 KEZ39401.1 - 1.5e-60 204.5 0.0 1.9e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KEZ39401.1 - 0.0018 17.8 0.1 0.1 12.1 0.2 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 KEZ39401.1 - 0.0025 18.5 4.2 0.0088 16.7 4.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ39401.1 - 0.0026 17.4 0.0 0.034 13.8 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.18 KEZ39401.1 - 0.031 13.8 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KEZ39401.1 - 0.044 13.1 0.1 0.7 9.1 0.0 2.5 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KEZ39401.1 - 0.15 11.8 0.1 9 6.0 0.6 3.0 3 1 0 3 3 3 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KEZ39401.1 - 0.3 9.7 0.2 0.44 9.2 0.2 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) NIPSNAP PF07978.13 KEZ39402.1 - 2e-41 140.4 0.8 3.1e-29 101.2 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.9 KEZ39403.1 - 8.6e-73 245.1 0.0 9.9e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein RhlB PF12300.8 KEZ39403.1 - 0.25 11.5 3.0 0.38 10.9 3.0 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Rpp20 PF12328.8 KEZ39404.1 - 8.2e-29 100.3 2.2 1e-28 100.0 2.2 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KEZ39404.1 - 6.2e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Alba DUF3614 PF12267.8 KEZ39404.1 - 0.028 14.9 1.6 0.034 14.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) ketoacyl-synt PF00109.26 KEZ39405.1 - 4.5e-71 239.4 0.0 1.7e-70 237.5 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ39405.1 - 2.4e-59 200.3 1.7 5.6e-59 199.1 0.8 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KEZ39405.1 - 4.9e-52 177.4 0.0 9.5e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEZ39405.1 - 3.9e-47 160.9 0.0 7.1e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEZ39405.1 - 1.8e-41 140.9 0.1 7.7e-41 138.8 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEZ39405.1 - 2.2e-18 66.7 0.0 7.6e-18 65.0 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEZ39405.1 - 1.1e-14 54.3 0.5 1.1e-14 54.3 0.5 2.4 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ39405.1 - 1.7e-14 55.0 0.1 1.7e-13 51.8 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ39405.1 - 5.6e-13 49.0 0.8 3.1e-12 46.6 0.1 2.7 2 1 1 3 3 3 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KEZ39405.1 - 7.9e-11 42.0 1.3 2.2e-10 40.5 1.3 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KEZ39405.1 - 3.7e-07 30.0 0.1 9.6e-07 28.7 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEZ39405.1 - 7.6e-06 26.2 0.2 9.2e-05 22.7 0.2 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KEZ39405.1 - 0.00019 20.9 0.1 0.00047 19.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KEZ39405.1 - 0.085 12.7 0.3 0.3 10.9 0.3 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sec23_helical PF04815.15 KEZ39405.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Sec23/Sec24 helical domain AflR PF08493.10 KEZ39405.1 - 2.6 7.4 7.8 20 4.5 5.0 2.3 2 0 0 2 2 2 0 Aflatoxin regulatory protein FSH1 PF03959.13 KEZ39406.1 - 3.2e-24 85.8 0.0 2.1e-23 83.1 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ABC_membrane PF00664.23 KEZ39407.1 - 3e-72 243.5 24.6 1.4e-44 152.8 5.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ39407.1 - 1e-64 217.1 0.0 1.4e-32 113.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ39407.1 - 1.4e-14 54.1 3.4 0.00068 19.1 0.5 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ39407.1 - 5.9e-08 33.3 1.1 0.018 15.4 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEZ39407.1 - 3.3e-07 30.6 0.5 0.049 13.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEZ39407.1 - 3e-06 26.9 3.1 0.0026 17.5 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEZ39407.1 - 5.4e-06 26.4 2.2 0.076 12.8 0.1 3.9 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEZ39407.1 - 6.4e-06 26.0 0.4 0.18 11.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KEZ39407.1 - 6.7e-06 26.1 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KEZ39407.1 - 0.00012 22.0 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KEZ39407.1 - 0.00019 20.4 2.4 0.38 9.5 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 KEZ39407.1 - 0.00042 19.9 0.3 0.35 10.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 KEZ39407.1 - 0.00071 20.1 3.1 0.11 13.0 0.2 2.3 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 KEZ39407.1 - 0.002 17.8 0.2 0.44 10.2 0.0 2.6 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 KEZ39407.1 - 0.0029 17.4 0.1 2.7 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KEZ39407.1 - 0.0032 17.7 1.2 1.8 8.9 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KEZ39407.1 - 0.0046 17.1 0.5 0.8 9.7 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 KEZ39407.1 - 0.01 15.4 0.0 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KEZ39407.1 - 0.017 15.7 0.0 8.9 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEZ39407.1 - 0.03 14.3 0.0 10 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 KEZ39407.1 - 0.038 13.8 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KEZ39407.1 - 0.06 13.6 0.1 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEZ39407.1 - 0.073 13.2 0.0 8.7 6.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KEZ39407.1 - 0.11 12.3 0.1 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF3237 PF11578.8 KEZ39408.1 - 3.2e-17 62.8 0.0 9.4e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3237) CAP PF00188.26 KEZ39409.1 - 3.2e-21 76.5 2.4 4.3e-21 76.0 2.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TonB_N PF16031.5 KEZ39409.1 - 0.0006 20.3 24.6 0.001 19.6 24.6 1.4 1 0 0 1 1 1 1 TonB polyproline region PRCC PF10253.9 KEZ39409.1 - 0.36 11.6 6.2 0.46 11.3 6.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Trypan_PARP PF05887.11 KEZ39409.1 - 9.9 6.1 37.3 25 4.8 37.3 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CHCH PF06747.13 KEZ39410.1 - 3.4e-06 27.0 14.4 0.00012 22.1 4.9 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KEZ39410.1 - 0.0012 18.8 5.8 0.041 13.9 2.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KEZ39410.1 - 0.002 18.1 8.7 0.36 10.9 2.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KEZ39410.1 - 0.24 11.2 5.8 5.1 6.9 3.7 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 KEZ39410.1 - 1.4 9.3 7.0 8.6 6.7 0.1 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Nup54 PF13874.6 KEZ39411.1 - 3.6e-39 134.1 0.2 3.6e-39 134.1 0.2 2.7 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KEZ39411.1 - 2.6e-15 55.7 6.6 5.2e-15 54.7 6.6 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DivIVA PF05103.13 KEZ39411.1 - 0.0017 18.5 3.2 0.0017 18.5 3.2 2.6 3 0 0 3 3 3 1 DivIVA protein YscO-like PF16789.5 KEZ39411.1 - 0.054 13.5 5.8 0.097 12.7 5.8 1.5 1 0 0 1 1 1 0 YscO-like protein Nucleoporin_FG PF13634.6 KEZ39411.1 - 0.062 14.2 5.3 0.1 13.5 5.3 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region FapA PF03961.13 KEZ39411.1 - 0.1 11.2 2.4 0.14 10.7 2.4 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 KEZ39411.1 - 2 9.0 6.3 8 7.0 0.0 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein GDC-P PF02347.16 KEZ39412.1 - 4.4e-171 569.4 0.0 1.7e-157 524.7 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KEZ39412.1 - 1.2e-09 37.7 0.0 4.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ39412.1 - 9.6e-06 25.1 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KEZ39412.1 - 0.00034 19.3 0.0 0.0047 15.5 0.0 2.1 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ39412.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SUR7 PF06687.12 KEZ39414.1 - 4.9e-33 114.5 9.5 6.6e-33 114.1 9.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.12 KEZ39414.1 - 0.0055 16.2 2.8 0.0091 15.5 2.8 1.5 1 0 0 1 1 1 1 Clc-like Amastin PF07344.11 KEZ39414.1 - 0.12 12.3 9.6 0.28 11.0 9.6 1.6 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF4064 PF13273.6 KEZ39414.1 - 0.24 11.7 7.8 5 7.5 0.1 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) Peptidase_C65 PF10275.9 KEZ39415.1 - 8.1e-67 225.2 0.0 1.2e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain FAM199X PF15814.5 KEZ39415.1 - 0.036 13.1 6.5 0.44 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein family FAM199X PCI PF01399.27 KEZ39416.1 - 5.3e-19 68.7 1.3 1.4e-18 67.4 0.2 2.4 3 0 0 3 3 3 1 PCI domain DUF4735 PF15882.5 KEZ39416.1 - 0.014 14.8 0.3 0.039 13.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) FeoC PF09012.10 KEZ39416.1 - 0.021 14.9 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator CWC25 PF12542.8 KEZ39417.1 - 3.5e-25 88.9 3.0 3.5e-25 88.9 3.0 4.3 2 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KEZ39417.1 - 6.2e-13 48.7 9.4 6.2e-13 48.7 9.4 4.5 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 KEZ39418.1 - 3.2e-52 176.4 0.0 4.2e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ39418.1 - 5e-20 71.9 0.0 1.2e-19 70.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ39418.1 - 2.3e-06 27.2 0.0 3.9e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEZ39418.1 - 0.082 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEZ39418.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glyco_hydro_16 PF00722.21 KEZ39419.1 - 6.2e-41 139.8 2.7 1.1e-40 139.0 2.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Citrate_synt PF00285.21 KEZ39420.1 - 5.5e-100 334.9 0.0 8e-100 334.4 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 KEZ39421.1 - 1.6e-198 660.5 0.9 1.8e-198 660.3 0.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family adh_short_C2 PF13561.6 KEZ39422.1 - 9e-58 195.6 0.1 1e-57 195.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ39422.1 - 5.1e-41 140.3 0.1 6.2e-41 140.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ39422.1 - 8.6e-08 32.3 0.6 1.5e-07 31.5 0.5 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEZ39422.1 - 0.0017 18.3 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KEZ39422.1 - 0.033 14.3 0.1 0.066 13.3 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.6 KEZ39422.1 - 0.036 14.8 0.0 0.074 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ChuX_HutX PF06228.13 KEZ39422.1 - 0.039 13.7 0.1 6.6 6.5 0.0 2.3 1 1 1 2 2 2 0 Haem utilisation ChuX/HutX RecC_C PF17946.1 KEZ39422.1 - 0.051 13.3 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Methyltransf_12 PF08242.12 KEZ39422.1 - 0.068 13.9 0.0 0.13 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KEZ39422.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Eno-Rase_NADH_b PF12242.8 KEZ39422.1 - 0.13 12.0 2.7 6.9 6.5 0.5 3.1 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SLATT_5 PF18160.1 KEZ39424.1 - 0.0019 17.6 0.1 0.0046 16.3 0.1 1.6 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 IF3_N PF05198.16 KEZ39424.1 - 0.066 13.5 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain DUF3040 PF11239.8 KEZ39424.1 - 0.86 9.9 5.1 0.31 11.3 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Pkinase PF00069.25 KEZ39425.1 - 7.9e-11 41.8 0.0 3e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Gln-synt_C PF00120.24 KEZ39426.1 - 8.3e-77 258.5 0.0 1e-76 258.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Pkinase PF00069.25 KEZ39427.1 - 6.3e-55 186.4 0.0 3.3e-52 177.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39427.1 - 5e-30 104.6 0.0 3.9e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ39427.1 - 6.2e-05 22.4 0.0 9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEZ39427.1 - 0.002 17.1 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KEZ39427.1 - 0.0039 16.3 0.1 0.0065 15.6 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KEZ39427.1 - 0.0046 15.8 0.0 0.0067 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Mem_trans PF03547.18 KEZ39428.1 - 5.2e-53 179.8 0.0 8.3e-53 179.2 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Nse5 PF08691.10 KEZ39428.1 - 0.13 10.9 0.4 0.2 10.3 0.4 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 DUF1240 PF06836.12 KEZ39428.1 - 0.83 10.2 4.9 0.23 12.0 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Putative_PNPOx PF01243.20 KEZ39429.1 - 5.4e-13 48.9 0.0 2.2e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KEZ39429.1 - 0.0015 18.5 0.0 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.14 KEZ39429.1 - 0.0034 15.9 0.3 0.0042 15.6 0.3 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component CPSase_L_D2 PF02786.17 KEZ39430.1 - 5.9e-72 241.6 0.0 8.9e-72 241.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KEZ39430.1 - 1.7e-37 127.8 0.0 3.6e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KEZ39430.1 - 2.1e-37 128.0 0.0 4.2e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KEZ39430.1 - 5e-16 58.3 2.1 1.6e-15 56.7 2.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEZ39430.1 - 2.6e-07 30.4 0.0 0.0046 16.8 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KEZ39430.1 - 2.1e-06 27.5 0.0 4.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 KEZ39430.1 - 0.00043 20.9 0.1 0.76 10.5 0.0 3.1 3 0 0 3 3 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 KEZ39430.1 - 0.0012 18.9 0.0 0.0028 17.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KEZ39430.1 - 0.014 14.6 0.1 6.1 6.0 0.0 2.8 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 KEZ39430.1 - 0.021 14.4 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GCV_H PF01597.19 KEZ39430.1 - 0.087 12.7 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 KEZ39430.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp TP_methylase PF00590.20 KEZ39431.1 - 7.1e-45 153.6 0.0 1.4e-44 152.6 0.0 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KEZ39431.1 - 1.3e-15 57.7 0.0 2.9e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 KEZ39431.1 - 6.7e-12 44.6 0.1 1.9e-11 43.2 0.1 1.9 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KEZ39431.1 - 2.7e-09 36.5 0.0 3.9e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal RRM_1 PF00076.22 KEZ39432.1 - 6.3e-15 54.7 0.0 8.8e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEZ39432.1 - 0.15 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_trans_2_3 PF13632.6 KEZ39433.1 - 4.5e-53 180.1 2.1 1.2e-52 178.7 2.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KEZ39433.1 - 1.6e-06 28.0 0.0 5.4e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ39433.1 - 0.00028 20.4 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 KEZ39434.1 - 3.7e-16 59.1 0.4 6.1e-16 58.4 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.7 KEZ39434.1 - 0.2 11.8 0.1 0.45 10.6 0.1 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain ABC_tran PF00005.27 KEZ39435.1 - 1.3e-47 161.8 0.0 9.5e-25 87.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KEZ39435.1 - 3.2e-15 56.7 4.1 9e-05 22.4 1.4 4.9 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ39435.1 - 1.8e-13 50.5 0.0 0.00018 21.0 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEZ39435.1 - 4.4e-10 40.4 0.1 1.5e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 KEZ39435.1 - 8.4e-07 28.8 0.1 2e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KEZ39435.1 - 9.5e-07 28.9 0.0 0.028 14.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KEZ39435.1 - 1.4e-06 27.9 0.4 0.017 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ39435.1 - 3.3e-06 27.1 0.1 0.034 14.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KEZ39435.1 - 3.5e-05 24.1 0.1 0.35 11.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEZ39435.1 - 0.00026 20.8 0.1 0.44 10.2 0.1 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KEZ39435.1 - 0.00027 21.5 0.0 0.87 10.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KEZ39435.1 - 0.00034 20.8 0.1 0.32 11.1 0.0 3.0 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 KEZ39435.1 - 0.00035 20.9 0.0 0.049 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEZ39435.1 - 0.00061 20.1 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KEZ39435.1 - 0.00088 19.7 0.0 1.5 9.3 0.0 3.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KEZ39435.1 - 0.0028 17.8 0.0 3.1 8.1 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KEZ39435.1 - 0.0033 17.6 0.0 5.2 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ39435.1 - 0.0058 16.4 0.1 2.3 7.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KEZ39435.1 - 0.0063 15.5 0.2 1.8 7.4 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KEZ39435.1 - 0.011 15.7 0.2 1 9.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 KEZ39435.1 - 0.015 15.3 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KEZ39435.1 - 0.016 14.8 0.0 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEZ39435.1 - 0.017 14.9 0.4 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEZ39435.1 - 0.018 15.4 0.0 5.2 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 KEZ39435.1 - 0.019 14.7 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KEZ39435.1 - 0.025 14.7 0.0 2.2 8.3 0.0 2.7 2 1 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 KEZ39435.1 - 0.029 13.5 0.0 0.87 8.7 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.6 KEZ39435.1 - 0.042 12.5 0.0 1.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.20 KEZ39435.1 - 0.045 12.3 0.0 0.52 8.8 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region DUF815 PF05673.13 KEZ39435.1 - 0.06 12.5 0.0 7 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KEZ39435.1 - 0.085 12.8 0.0 19 5.1 0.1 2.8 3 0 0 3 3 2 0 NTPase MukB PF04310.12 KEZ39435.1 - 0.099 12.4 0.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal Zeta_toxin PF06414.12 KEZ39435.1 - 0.11 11.8 0.2 36 3.5 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_7 PF12775.7 KEZ39435.1 - 0.13 11.8 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3584 PF12128.8 KEZ39435.1 - 0.2 9.1 0.6 5.5 4.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HET PF06985.11 KEZ39436.1 - 3.7e-26 92.2 0.0 5.8e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CVNH PF08881.10 KEZ39437.1 - 1e-10 42.1 0.4 8.6e-06 26.4 0.1 2.1 1 1 1 2 2 2 2 CVNH domain tRNA_SAD PF07973.14 KEZ39437.1 - 0.081 13.0 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Spc7 PF08317.11 KEZ39439.1 - 2.1e-12 46.6 120.1 6.4e-08 31.8 9.9 6.4 2 1 5 7 7 7 4 Spc7 kinetochore protein ATG16 PF08614.11 KEZ39439.1 - 1.8e-09 38.1 132.6 2.9e-06 27.6 4.0 8.1 2 1 5 7 7 6 5 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 KEZ39439.1 - 1.8e-07 31.3 48.1 0.02 15.0 0.6 7.3 3 3 4 7 7 7 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KEZ39439.1 - 1.9e-06 28.1 9.7 2.4e-05 24.5 1.5 8.2 4 3 4 8 8 8 3 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 KEZ39439.1 - 1.1e-05 24.9 96.9 0.032 13.6 10.0 5.6 2 2 2 5 5 5 4 Domain of unknown function (DUF4407) DUF2935 PF11155.8 KEZ39439.1 - 3.1e-05 24.3 0.1 8.9 6.7 0.1 4.5 4 2 0 4 4 3 0 Domain of unknown function (DUF2935) GAS PF13851.6 KEZ39439.1 - 8.7e-05 22.0 106.9 0.0038 16.6 15.0 7.7 2 2 4 6 6 6 3 Growth-arrest specific micro-tubule binding MAD PF05557.13 KEZ39439.1 - 0.00018 20.1 13.6 0.00018 20.1 13.6 4.3 1 1 2 4 4 4 3 Mitotic checkpoint protein KASH_CCD PF14662.6 KEZ39439.1 - 0.00024 21.0 31.3 0.00024 21.0 31.3 7.0 2 2 4 6 6 6 3 Coiled-coil region of CCDC155 or KASH ERM PF00769.19 KEZ39439.1 - 0.00075 19.4 18.9 0.00075 19.4 18.9 6.4 1 1 4 6 6 5 2 Ezrin/radixin/moesin family DUF4201 PF13870.6 KEZ39439.1 - 0.0013 18.5 96.6 0.023 14.4 15.2 7.8 2 2 3 6 6 6 4 Domain of unknown function (DUF4201) AAA_13 PF13166.6 KEZ39439.1 - 0.002 16.9 21.2 0.002 16.9 21.2 3.8 1 1 3 4 4 4 1 AAA domain CENP-F_leu_zip PF10473.9 KEZ39439.1 - 0.0024 17.9 132.1 0.035 14.1 10.1 7.7 2 2 6 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC144C PF14915.6 KEZ39439.1 - 0.003 16.7 23.6 0.003 16.7 23.6 5.2 1 1 3 4 4 2 1 CCDC144C protein coiled-coil region HAP1_N PF04849.13 KEZ39439.1 - 0.0036 16.5 10.7 0.0036 16.5 10.7 5.4 2 2 4 6 6 4 1 HAP1 N-terminal conserved region DUF3552 PF12072.8 KEZ39439.1 - 0.0044 16.5 11.9 0.0044 16.5 11.9 7.0 1 1 5 6 6 3 2 Domain of unknown function (DUF3552) ZapB PF06005.12 KEZ39439.1 - 0.0046 17.4 1.9 0.0046 17.4 1.9 13.1 2 2 6 8 8 6 3 Cell division protein ZapB DUF16 PF01519.16 KEZ39439.1 - 0.0057 17.1 3.5 0.0057 17.1 3.5 9.2 2 2 2 5 5 3 1 Protein of unknown function DUF16 TolA_bind_tri PF16331.5 KEZ39439.1 - 0.0073 16.4 4.1 0.0073 16.4 4.1 10.6 4 4 6 11 11 11 1 TolA binding protein trimerisation ADIP PF11559.8 KEZ39439.1 - 0.016 15.3 0.2 0.016 15.3 0.2 9.3 2 2 7 9 9 8 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KEZ39439.1 - 0.025 13.7 0.4 0.025 13.7 0.4 4.6 2 2 0 3 3 1 0 Myosin-like coiled-coil protein GP3_package PF16677.5 KEZ39439.1 - 0.026 14.7 0.7 5 7.3 0.0 3.0 1 1 1 2 2 2 0 DNA-packaging protein gp3 DUF3450 PF11932.8 KEZ39439.1 - 0.033 13.5 0.2 0.013 14.9 6.2 9.1 1 1 8 9 9 9 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 KEZ39439.1 - 0.035 14.2 0.0 0.035 14.2 0.0 14.8 5 4 12 17 17 17 0 bZIP transcription factor MscS_porin PF12795.7 KEZ39439.1 - 0.036 13.6 109.0 0.017 14.6 10.8 5.8 1 1 3 5 5 4 0 Mechanosensitive ion channel porin domain LPP PF04728.13 KEZ39439.1 - 0.044 14.2 40.7 0.33 11.4 0.0 9.5 6 2 2 8 8 8 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.22 KEZ39439.1 - 0.075 13.3 0.4 0.075 13.3 0.4 9.8 2 2 7 9 9 9 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 KEZ39439.1 - 0.076 13.5 56.0 2 8.9 4.2 10.3 4 3 4 8 8 6 0 Nucleopolyhedrovirus P10 protein SHE3 PF17078.5 KEZ39439.1 - 0.084 12.6 81.7 0.032 14.0 1.7 6.4 3 3 2 5 5 5 0 SWI5-dependent HO expression protein 3 PKcGMP_CC PF16808.5 KEZ39439.1 - 0.2 11.6 0.0 0.2 11.6 0.0 8.6 7 1 0 9 9 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 KEZ39439.1 - 0.29 10.2 96.1 0.13 11.3 8.2 6.1 2 1 3 5 5 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KEZ39439.1 - 0.38 11.3 140.7 0.53 10.8 3.7 8.4 1 1 7 8 8 7 0 Apg6 coiled-coil region ubiquitin PF00240.23 KEZ39439.1 - 0.42 10.4 4.0 31 4.4 0.0 4.6 3 1 0 4 4 4 0 Ubiquitin family TMF_DNA_bd PF12329.8 KEZ39439.1 - 0.7 9.9 130.5 0.031 14.3 1.6 13.5 3 3 10 14 14 13 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 KEZ39439.1 - 0.78 9.2 107.9 0.39 10.1 19.9 6.2 2 1 4 6 6 6 0 Golgin subfamily A member 5 TACC_C PF05010.14 KEZ39439.1 - 1 9.1 90.8 0.063 13.1 12.5 6.4 2 1 3 6 6 6 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UPF0242 PF06785.11 KEZ39439.1 - 1.5 8.9 117.0 0.27 11.3 18.9 7.2 1 1 4 5 5 4 0 Uncharacterised protein family (UPF0242) N-terminus FPP PF05911.11 KEZ39439.1 - 1.6 6.8 100.2 0.021 13.0 25.0 5.4 2 1 4 7 7 7 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 KEZ39439.1 - 2.8 8.4 107.9 3.9 7.9 11.7 6.7 1 1 4 6 6 6 0 Fez1 DUF2353 PF09789.9 KEZ39439.1 - 3.6 6.8 97.1 0.63 9.3 8.6 5.5 1 1 5 6 6 5 0 Uncharacterized coiled-coil protein (DUF2353) DUF1664 PF07889.12 KEZ39439.1 - 4.3 7.4 67.9 0.038 14.0 0.9 8.5 2 2 8 10 10 10 0 Protein of unknown function (DUF1664) HOOK PF05622.12 KEZ39439.1 - 4.6 5.3 116.5 0.033 12.3 10.2 6.0 2 1 3 5 5 4 0 HOOK protein CEP63 PF17045.5 KEZ39439.1 - 5 6.9 98.8 1.5 8.7 9.5 6.8 2 1 4 6 6 6 0 Centrosomal protein of 63 kDa Fib_alpha PF08702.10 KEZ39439.1 - 5.6 7.1 59.0 1.3 9.2 6.6 6.9 3 3 4 7 7 7 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KEZ39439.1 - 8.3 3.8 107.8 0.036 11.6 7.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) MFS_1 PF07690.16 KEZ39440.1 - 1.2e-33 116.6 14.1 3e-33 115.2 13.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39440.1 - 4.3e-08 32.4 5.5 1e-05 24.6 7.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KEZ39440.1 - 1.5e-05 23.6 5.8 0.00028 19.4 5.0 2.3 2 0 0 2 2 2 1 Transmembrane secretion effector Folate_carrier PF01770.18 KEZ39440.1 - 0.027 13.2 0.0 0.042 12.6 0.0 1.4 1 0 0 1 1 1 0 Reduced folate carrier LacY_symp PF01306.19 KEZ39440.1 - 0.99 8.1 6.2 2.4 6.8 2.0 2.4 2 0 0 2 2 2 0 LacY proton/sugar symporter MFS_1_like PF12832.7 KEZ39440.1 - 4.4 6.1 14.1 0.046 12.6 2.7 2.6 3 0 0 3 3 3 0 MFS_1 like family DUF1590 PF07629.11 KEZ39440.1 - 5.7 6.8 14.4 2.7 7.9 5.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) PTR2 PF00854.21 KEZ39441.1 - 2.2e-36 125.6 0.0 2.5e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 POT family Glyco_hydr_116N PF12215.8 KEZ39441.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Ank_2 PF12796.7 KEZ39442.1 - 1.4e-67 224.3 0.1 2.7e-19 69.5 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ39442.1 - 1.5e-48 162.2 4.5 3.4e-13 49.5 0.1 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ39442.1 - 1.8e-47 159.1 1.0 5.3e-13 49.2 0.0 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KEZ39442.1 - 5.2e-46 153.1 1.7 1.1e-07 31.9 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.6 KEZ39442.1 - 2.8e-41 134.7 0.0 4.6e-06 26.6 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Nitro_FeMo-Co PF02579.17 KEZ39442.1 - 0.0031 17.8 0.2 3.4 8.1 0.0 3.1 1 1 2 3 3 3 2 Dinitrogenase iron-molybdenum cofactor DUF4350 PF14258.6 KEZ39442.1 - 0.007 16.8 1.2 3.5 8.1 0.0 3.8 4 1 1 5 5 5 1 Domain of unknown function (DUF4350) PEGA PF08308.11 KEZ39442.1 - 0.007 16.2 0.0 21 5.1 0.0 4.3 4 1 1 5 5 5 0 PEGA domain Imm_superinfect PF14373.6 KEZ39442.1 - 0.039 13.9 0.2 23 5.0 0.0 3.6 3 0 0 3 3 3 0 Superinfection immunity protein DUF1403 PF07183.11 KEZ39442.1 - 0.091 12.3 2.3 5.5 6.4 0.1 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1403) VWA_3_C PF18571.1 KEZ39442.1 - 0.2 11.6 9.7 5.5 6.9 0.2 4.2 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain NAD_binding_8 PF13450.6 KEZ39443.1 - 2.9e-13 49.8 0.7 7.3e-13 48.6 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Acetyltransf_1 PF00583.25 KEZ39443.1 - 1.1e-09 38.6 0.0 2.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ39443.1 - 5.2e-08 32.9 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ39443.1 - 1.2e-06 28.9 0.0 4.1e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Amino_oxidase PF01593.24 KEZ39443.1 - 2.8e-05 23.6 0.0 7.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 KEZ39443.1 - 3.3e-05 23.6 0.1 6.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ39443.1 - 4.4e-05 22.7 0.4 7.5e-05 22.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEZ39443.1 - 6.3e-05 22.5 0.6 9.8e-05 21.9 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Acetyltransf_CG PF14542.6 KEZ39443.1 - 0.00018 21.6 0.0 0.00043 20.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Thi4 PF01946.17 KEZ39443.1 - 0.00028 20.2 0.2 0.00057 19.2 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KEZ39443.1 - 0.0034 16.2 1.0 0.0049 15.6 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KEZ39443.1 - 0.0037 16.6 0.3 0.0067 15.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KEZ39443.1 - 0.0045 17.5 1.3 0.02 15.4 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ39443.1 - 0.0095 15.2 0.1 0.024 13.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FR47 PF08445.10 KEZ39443.1 - 0.022 14.7 0.0 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Pyr_redox_3 PF13738.6 KEZ39443.1 - 0.083 12.1 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ39443.1 - 0.12 11.2 0.4 0.19 10.5 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Acetyltransf_9 PF13527.7 KEZ39443.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_23 PF13489.6 KEZ39444.1 - 6.2e-19 68.4 0.0 9.3e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39444.1 - 1.3e-12 48.2 0.0 3.1e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39444.1 - 1.4e-10 41.6 0.0 2.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39444.1 - 1.3e-09 38.7 0.0 5.5e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39444.1 - 2.3e-05 24.3 0.0 0.02 14.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ39444.1 - 0.00017 21.0 0.0 0.002 17.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 KEZ39444.1 - 0.0048 16.4 0.0 0.0096 15.5 0.0 1.5 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 KEZ39444.1 - 0.0063 16.0 0.0 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 KEZ39444.1 - 0.0082 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KEZ39444.1 - 0.017 14.6 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.12 KEZ39444.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KEZ39444.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase NUDIX PF00293.28 KEZ39444.1 - 0.1 12.6 0.1 0.25 11.4 0.0 1.7 2 0 0 2 2 1 0 NUDIX domain CMAS PF02353.20 KEZ39444.1 - 0.1 11.9 0.0 0.65 9.2 0.0 2.2 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.16 KEZ39445.1 - 2.5e-20 72.7 29.1 5.5e-12 45.3 6.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ39445.1 - 0.00024 20.5 0.7 0.00024 20.5 0.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Myb_DNA-binding PF00249.31 KEZ39445.1 - 0.16 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2085 PF09858.9 KEZ39445.1 - 5.9 7.4 8.8 41 4.7 0.6 3.5 2 1 0 3 3 3 0 Predicted membrane protein (DUF2085) FAD_binding_3 PF01494.19 KEZ39446.1 - 1.3e-97 327.2 0.0 1.7e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ39446.1 - 1.3e-06 27.9 0.0 2.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ39446.1 - 9.9e-06 25.4 0.0 0.03 13.9 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ39446.1 - 0.0059 15.4 0.1 0.61 8.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KEZ39446.1 - 0.026 15.1 0.0 5 7.8 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEZ39446.1 - 0.06 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ39446.1 - 0.065 13.5 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ39446.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAA_hydrolase PF01557.18 KEZ39447.1 - 8.2e-63 212.0 0.0 9.9e-63 211.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FmdE PF02663.14 KEZ39447.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Glyoxalase PF00903.25 KEZ39448.1 - 2.2e-06 27.9 1.3 0.00017 21.8 0.5 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Clavanin PF05452.11 KEZ39449.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Clavanin HET PF06985.11 KEZ39450.1 - 1.5e-29 103.2 0.0 2.7e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec3_C PF09763.9 KEZ39451.1 - 6.8e-193 642.9 0.0 9.9e-193 642.3 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KEZ39451.1 - 1.9e-28 98.4 0.0 3.8e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 KEZ39451.1 - 0.012 14.4 2.5 0.068 11.9 0.0 2.8 3 0 0 3 3 3 0 Vps52 / Sac2 family Sec3_C_2 PF15278.6 KEZ39451.1 - 0.14 12.5 0.2 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Sec3 exocyst complex subunit FeoB_Cyto PF17910.1 KEZ39451.1 - 0.16 12.5 1.3 16 6.1 0.2 3.4 2 1 1 3 3 3 0 FeoB cytosolic helical domain DUF4795 PF16043.5 KEZ39451.1 - 0.34 10.5 2.7 20 4.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) SIR2_2 PF13289.6 KEZ39453.1 - 0.081 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 SIR2-like domain ERCC3_RAD25_C PF16203.5 KEZ39455.1 - 3.7e-84 281.8 0.0 9.5e-84 280.5 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RXT2_N PF08595.11 KEZ39455.1 - 8.7e-42 142.8 0.0 8.7e-42 142.8 0.0 4.2 5 0 0 5 5 5 1 RXT2-like, N-terminal Helicase_C_3 PF13625.6 KEZ39455.1 - 1.2e-33 116.0 0.0 3e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 KEZ39455.1 - 2.7e-10 40.6 0.2 9e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ39455.1 - 5e-10 39.6 0.0 3.9e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HNH_2 PF13391.6 KEZ39456.1 - 1.1e-06 28.7 0.5 1.9e-06 27.9 0.5 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF4464 PF14713.6 KEZ39457.1 - 0.013 15.1 6.7 0.031 13.8 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) Nrap_D6 PF17407.2 KEZ39457.1 - 0.048 13.9 0.0 2.2 8.5 0.1 2.7 2 0 0 2 2 2 0 Nrap protein domain 6 ApoM PF11032.8 KEZ39457.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 ApoM domain Gryzun PF07919.12 KEZ39458.1 - 5.3e-215 715.7 0.0 6.4e-215 715.4 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KEZ39458.1 - 7.1e-86 288.0 0.5 1.6e-78 263.9 1.0 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KEZ39458.1 - 0.04 13.9 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking RXT2_N PF08595.11 KEZ39458.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Abhydrolase_6 PF12697.7 KEZ39459.1 - 2.4e-14 54.5 2.2 4.2e-14 53.7 2.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ39459.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ39459.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 KEZ39460.1 - 1.2e-68 231.4 0.0 1.7e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39460.1 - 1.4e-30 106.4 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ39460.1 - 0.00018 20.9 0.0 0.00037 19.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ39460.1 - 0.0015 18.5 0.1 0.0073 16.3 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEZ39460.1 - 0.0019 17.2 0.0 0.021 13.8 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KEZ39460.1 - 0.011 15.0 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KEZ39460.1 - 0.029 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 KEZ39461.1 - 5.9e-29 101.7 0.0 3.5e-27 95.9 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_7 PF00840.20 KEZ39462.1 - 7e-199 661.0 13.2 7.9e-199 660.8 13.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fapy_DNA_glyco PF01149.24 KEZ39463.1 - 2.4e-36 124.9 1.0 6.1e-36 123.6 0.0 2.1 2 1 1 3 3 3 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KEZ39463.1 - 6.1e-21 74.2 0.0 1.6e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Mating_N PF12731.7 KEZ39464.1 - 0.011 15.7 0.3 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 zinc_ribbon_4 PF13717.6 KEZ39465.1 - 0.36 10.8 3.3 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_3 PF13878.6 KEZ39465.1 - 1.2 9.0 4.7 9.8 6.1 0.1 2.9 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO Anti-TRAP PF15777.5 KEZ39465.1 - 3.2 7.8 10.6 7.1 6.7 1.3 3.0 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Clr5 PF14420.6 KEZ39466.1 - 1.6e-08 34.7 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Clr5 domain PH PF00169.29 KEZ39467.1 - 0.00074 20.0 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 KEZ39467.1 - 0.47 10.3 5.3 0.55 10.1 3.6 1.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Arrestin_C PF02752.22 KEZ39468.1 - 1.2e-14 54.9 0.0 2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KEZ39468.1 - 1e-11 45.1 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KEZ39468.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Arrestin_N terminal like WD40 PF00400.32 KEZ39469.1 - 8.6e-14 51.7 9.8 2.4e-05 25.0 0.5 4.7 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39469.1 - 4.1e-10 39.8 0.1 0.0043 17.3 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEZ39469.1 - 0.00017 21.5 0.0 0.00059 19.8 0.0 1.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KEZ39469.1 - 0.003 15.6 0.0 0.0042 15.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family PD40 PF07676.12 KEZ39469.1 - 0.013 15.4 0.0 5 7.2 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KEZ39469.1 - 0.039 12.5 0.0 0.15 10.5 0.0 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain VID27 PF08553.10 KEZ39469.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Lactamase_B_4 PF13691.6 KEZ39469.1 - 0.27 10.9 0.9 7.3 6.4 0.0 3.1 4 0 0 4 4 4 0 tRNase Z endonuclease EF_assoc_1 PF08355.12 KEZ39470.1 - 8.2e-32 108.6 0.1 1.7e-31 107.6 0.1 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 KEZ39470.1 - 1.7e-26 92.0 0.0 3.5e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KEZ39470.1 - 1.8e-19 69.9 0.0 1.7e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEZ39470.1 - 2.3e-11 44.0 0.0 4.7e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 KEZ39470.1 - 1.1e-09 37.1 2.6 0.00054 19.3 0.7 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KEZ39470.1 - 3.9e-09 36.8 1.5 0.00019 21.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEZ39470.1 - 3.9e-09 35.7 4.1 0.00021 21.0 0.8 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KEZ39470.1 - 3.2e-08 32.7 7.3 0.00022 20.6 2.5 2.8 3 0 0 3 3 3 2 EF hand MMR_HSR1 PF01926.23 KEZ39470.1 - 3.2e-07 30.4 0.0 0.022 14.8 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEZ39470.1 - 5.3e-05 23.4 0.0 0.41 10.7 0.1 3.2 3 0 0 3 3 3 2 Dynamin family AAA_16 PF13191.6 KEZ39470.1 - 7.5e-05 23.2 0.0 0.03 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KEZ39470.1 - 0.00016 21.3 0.0 0.021 14.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ39470.1 - 0.0026 18.1 0.0 0.31 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SPARC_Ca_bdg PF10591.9 KEZ39470.1 - 0.0026 18.0 0.0 3.8 7.9 0.0 3.3 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region ABC_tran PF00005.27 KEZ39470.1 - 0.0056 17.2 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 KEZ39470.1 - 0.012 15.3 0.1 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 KEZ39470.1 - 0.013 14.6 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain AAA_28 PF13521.6 KEZ39470.1 - 0.016 15.4 0.1 5.3 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KEZ39470.1 - 0.037 13.9 0.1 6.7 6.6 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase IIGP PF05049.13 KEZ39470.1 - 0.042 12.9 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) UCR_Fe-S_N PF10399.9 KEZ39470.1 - 0.059 12.7 0.2 0.14 11.5 0.2 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ploopntkinase3 PF18751.1 KEZ39470.1 - 0.079 12.9 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 KEZ39470.1 - 0.12 11.8 0.1 0.9 8.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family EF-hand_10 PF14788.6 KEZ39470.1 - 0.12 12.3 1.5 3.9 7.4 0.1 2.6 2 0 0 2 2 2 0 EF hand ATP_bind_1 PF03029.17 KEZ39470.1 - 0.17 11.7 0.0 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein EF-hand_8 PF13833.6 KEZ39470.1 - 0.26 11.2 4.0 2.4 8.0 0.8 2.6 2 0 0 2 2 2 0 EF-hand domain pair RPN7 PF10602.9 KEZ39471.1 - 3.8e-55 186.3 0.3 1.5e-54 184.3 0.0 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KEZ39471.1 - 6.5e-16 58.7 0.0 1.5e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain Aminotran_1_2 PF00155.21 KEZ39472.1 - 4.6e-40 137.9 0.0 6.6e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ39472.1 - 0.005 15.4 0.0 0.0084 14.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ribosomal_L33 PF00471.20 KEZ39473.1 - 4.8e-07 30.1 0.0 6.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 ATG16 PF08614.11 KEZ39474.1 - 0.00012 22.3 9.6 0.00012 22.3 9.6 4.8 2 2 2 4 4 4 2 Autophagy protein 16 (ATG16) CD99L2 PF12301.8 KEZ39475.1 - 0.013 15.8 0.3 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 CD99 antigen like protein 2 NUC153 PF08159.12 KEZ39476.1 - 6.3e-10 38.7 0.1 1.1e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KEZ39476.1 - 7.3e-08 33.0 0.3 0.001 19.9 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39476.1 - 0.00072 19.8 0.0 0.003 17.8 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PNP_UDP_1 PF01048.20 KEZ39477.1 - 1.5e-40 138.9 0.2 2.5e-40 138.2 0.2 1.3 2 0 0 2 2 2 1 Phosphorylase superfamily DUF3512 PF12024.8 KEZ39477.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Med13_C PF06333.12 KEZ39478.1 - 1.2e-91 307.5 0.2 2.6e-91 306.3 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KEZ39478.1 - 3.6e-30 105.4 1.4 5.9e-30 104.7 1.4 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KEZ39478.1 - 2.5e-12 47.1 0.1 2.7e-05 24.1 0.2 2.5 2 0 0 2 2 2 2 MID domain of medPIWI K-cyclin_vir_C PF09080.10 KEZ39478.1 - 0.012 16.0 0.9 0.12 12.8 0.2 2.9 3 0 0 3 3 3 0 K cyclin, C terminal Mustang PF15682.5 KEZ39478.1 - 0.076 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Atx10homo_assoc PF09759.9 KEZ39479.1 - 2e-09 37.3 0.0 6.1e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain NicO PF03824.16 KEZ39479.1 - 0.087 12.2 3.7 0.14 11.5 3.7 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 KEZ39479.1 - 1.5 8.2 26.4 2.5 7.4 26.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 KEZ39480.1 - 5.6e-56 190.2 0.0 9.3e-56 189.4 0.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 KEZ39481.1 - 6.6e-25 88.0 12.4 9e-25 87.6 12.4 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEZ39481.1 - 1.6e-08 34.5 0.2 3.5e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter RCDG1 PF15725.5 KEZ39481.1 - 0.16 12.4 3.2 0.41 11.1 3.2 1.7 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein IBV_3C PF03620.13 KEZ39481.1 - 0.16 12.5 3.0 10 6.7 0.3 2.5 1 1 1 2 2 2 0 IBV 3C protein MRP-L27 PF09809.9 KEZ39482.1 - 8.6e-17 61.0 0.4 1.2e-16 60.6 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_3 PF07859.13 KEZ39483.1 - 4.4e-43 147.6 0.1 2.2e-32 112.7 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEZ39483.1 - 5.7e-15 55.1 0.0 2.7e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KEZ39483.1 - 0.003 16.5 0.6 0.03 13.2 0.6 2.1 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 KEZ39483.1 - 0.052 12.8 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 KEZ39483.1 - 0.092 12.3 0.1 0.41 10.2 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3089) WGG PF10273.9 KEZ39484.1 - 7.3e-26 90.7 0.1 1.1e-25 90.1 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KEZ39484.1 - 0.042 14.0 0.8 0.075 13.2 0.1 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CENP-B_dimeris PF09026.10 KEZ39484.1 - 0.6 10.5 12.2 1.5 9.2 12.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KEZ39484.1 - 1.6 8.0 6.5 2 7.6 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KEZ39484.1 - 3.3 7.7 5.2 3.4 7.7 3.9 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal YL1 PF05764.13 KEZ39484.1 - 6.4 6.8 8.7 7.4 6.6 8.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BSD PF03909.17 KEZ39485.1 - 6.7e-20 70.9 0.3 1.4e-19 69.8 0.3 1.6 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 KEZ39485.1 - 0.47 10.4 6.2 0.059 13.3 1.9 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PAP1 PF08601.10 KEZ39486.1 - 2.2e-71 241.6 28.5 2.2e-71 241.6 28.5 3.5 2 2 0 2 2 1 1 Transcription factor PAP1 bZIP_1 PF00170.21 KEZ39486.1 - 7.2e-07 29.2 13.5 7.2e-07 29.2 13.5 2.0 2 1 0 2 2 2 1 bZIP transcription factor SHE3 PF17078.5 KEZ39486.1 - 0.0002 21.2 4.5 0.00034 20.4 4.5 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KEZ39486.1 - 0.0012 18.9 9.0 0.0028 17.7 9.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Calici_PP_N PF08405.11 KEZ39486.1 - 0.037 12.8 0.1 0.056 12.3 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal APG6_N PF17675.1 KEZ39486.1 - 0.058 13.9 3.0 0.11 13.1 3.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF812 PF05667.11 KEZ39486.1 - 0.1 11.5 5.1 0.13 11.1 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TMCO5 PF14992.6 KEZ39486.1 - 0.19 11.3 4.6 0.31 10.6 4.6 1.2 1 0 0 1 1 1 0 TMCO5 family Lebercilin PF15619.6 KEZ39486.1 - 0.2 11.3 8.3 0.37 10.4 8.3 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 KEZ39486.1 - 0.36 10.9 3.9 0.61 10.2 3.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 KEZ39486.1 - 1 9.6 3.6 1.8 8.9 3.6 1.3 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_Maf PF03131.17 KEZ39486.1 - 1.3 9.6 9.7 2.9 8.5 9.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Fungal_trans PF04082.18 KEZ39487.1 - 3.7e-10 39.3 0.0 5.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ39487.1 - 3.5e-06 27.0 13.3 5.9e-06 26.3 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.19 KEZ39488.1 - 1.6e-09 37.2 0.0 1.9e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEZ39488.1 - 0.0028 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KEZ39488.1 - 0.24 9.9 0.0 0.37 9.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 KEZ39489.1 - 1.9e-144 481.7 0.0 2.2e-144 481.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Zn_clus PF00172.18 KEZ39490.1 - 3.4e-05 23.9 10.1 6.6e-05 23.0 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ39490.1 - 0.0011 18.1 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KEZ39491.1 - 1.4e-17 64.0 0.3 1.7e-16 60.5 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ39491.1 - 2e-08 34.4 0.4 5e-08 33.1 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ39491.1 - 6.6e-07 29.2 0.3 1.2e-06 28.3 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ39491.1 - 1.4e-06 27.7 1.0 0.0021 17.2 0.6 2.1 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KEZ39491.1 - 1.5e-05 24.4 0.3 2.6e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ39491.1 - 0.00031 20.2 0.1 0.00043 19.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ39491.1 - 0.00034 21.1 1.0 0.00088 19.8 1.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ39491.1 - 0.005 15.9 0.1 0.0066 15.5 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KEZ39491.1 - 0.0057 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Rossmann-like PF10727.9 KEZ39491.1 - 0.027 14.3 0.4 0.053 13.4 0.4 1.5 1 0 0 1 1 1 0 Rossmann-like domain HI0933_like PF03486.14 KEZ39491.1 - 0.041 12.6 0.8 0.062 12.0 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KEZ39491.1 - 0.045 12.8 1.0 0.065 12.3 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KEZ39491.1 - 0.055 13.4 1.3 0.092 12.6 1.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KEZ39491.1 - 0.13 11.5 0.3 0.26 10.5 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 KEZ39491.1 - 0.22 11.5 0.4 0.36 10.8 0.4 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KEZ39491.1 - 0.25 11.0 2.1 0.5 10.0 0.8 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Amidohydro_2 PF04909.14 KEZ39492.1 - 2.4e-37 129.3 0.3 3.1e-37 128.9 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase FcoT PF10862.8 KEZ39492.1 - 0.15 11.6 0.2 1.6 8.3 0.2 2.4 2 1 1 3 3 3 0 FcoT-like thioesterase domain Pkinase PF00069.25 KEZ39493.1 - 3e-08 33.4 0.0 3.7e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39493.1 - 0.0014 17.9 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pyr_redox_3 PF13738.6 KEZ39494.1 - 3.7e-16 59.3 0.0 1.7e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEZ39494.1 - 1.1e-15 57.1 0.0 2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEZ39494.1 - 3.3e-15 56.1 0.0 1.2e-13 51.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ39494.1 - 4.8e-15 55.6 0.0 7.7e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ39494.1 - 7.5e-09 35.2 0.6 0.00013 21.3 0.0 2.6 3 0 0 3 3 3 2 Thi4 family NAD_binding_8 PF13450.6 KEZ39494.1 - 4.7e-07 30.0 0.4 0.00035 20.7 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ39494.1 - 1.7e-05 24.6 1.8 0.088 12.4 0.0 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ39494.1 - 5.1e-05 23.8 1.0 0.04 14.5 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ39494.1 - 0.0011 18.2 1.2 6.6 5.7 0.2 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KEZ39494.1 - 0.0012 18.9 0.3 0.41 10.6 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEZ39494.1 - 0.01 15.0 1.1 1 8.4 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KEZ39494.1 - 0.025 13.3 1.8 1.9 7.1 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KEZ39494.1 - 0.033 13.2 0.3 3.1 6.8 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KEZ39494.1 - 0.099 12.0 0.2 9.2 5.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short_C2 PF13561.6 KEZ39495.1 - 2.5e-59 200.7 0.4 2.9e-59 200.4 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ39495.1 - 2.4e-46 157.7 0.8 3e-46 157.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ39495.1 - 1.1e-13 51.5 0.3 2.2e-13 50.5 0.3 1.5 1 1 1 2 2 2 1 KR domain Glyco_transf_5 PF08323.11 KEZ39495.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.5 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF43 PF01861.16 KEZ39495.1 - 0.068 12.4 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain SnoaL PF07366.12 KEZ39496.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 KEZ39497.1 - 3e-28 98.9 0.0 3.4e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Fe-ADH PF00465.19 KEZ39498.1 - 2e-103 346.0 0.0 2.6e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KEZ39498.1 - 7.9e-16 58.5 0.0 1e-11 45.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KEZ39498.1 - 0.0022 17.7 0.1 0.0053 16.5 0.1 1.5 2 0 0 2 2 2 1 Periplasmic binding protein Pkinase PF00069.25 KEZ39499.1 - 1.3e-58 198.5 0.0 1.7e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39499.1 - 1.4e-30 106.4 0.0 2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ39499.1 - 0.00045 19.6 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ39499.1 - 0.014 15.3 1.7 0.015 15.3 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KEZ39499.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ39499.1 - 0.015 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase eRF1_1 PF03463.15 KEZ39499.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 eRF1 domain 1 HECT PF00632.25 KEZ39500.1 - 1.6e-65 221.6 0.0 2.4e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KEZ39500.1 - 5.1e-21 74.7 1.3 1.2e-20 73.5 1.3 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 KEZ39501.1 - 1.9e-35 121.2 7.1 3e-28 98.1 1.1 3.7 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEZ39501.1 - 4.9e-12 45.8 11.9 8.9e-07 29.0 4.3 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ39501.1 - 1.3e-06 28.6 4.4 1.3e-06 28.6 4.4 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type SnoaL_2 PF12680.7 KEZ39501.1 - 0.031 14.9 0.2 0.17 12.5 0.1 2.2 2 0 0 2 2 2 0 SnoaL-like domain zf-C2H2_4 PF13894.6 KEZ39501.1 - 0.041 14.7 16.3 0.43 11.5 0.6 5.0 5 0 0 5 5 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ39501.1 - 0.11 13.0 20.1 1.5 9.4 1.4 4.8 4 1 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.12 KEZ39501.1 - 0.72 10.1 6.9 9.3 6.5 0.0 3.2 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-3CxxC_2 PF17180.4 KEZ39501.1 - 2.1 9.2 15.0 1.5 9.6 0.0 4.1 5 0 0 5 5 4 0 Zinc-binding domain BLOC1S3 PF15753.5 KEZ39501.1 - 2.9 8.0 8.5 0.81 9.8 1.0 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 NADH-G_4Fe-4S_3 PF10588.9 KEZ39501.1 - 8.3 6.0 6.8 9.1 5.9 0.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-DBF PF07535.12 KEZ39501.1 - 9.3 6.5 13.0 4.9 7.4 1.8 3.4 4 0 0 4 4 4 0 DBF zinc finger DHBP_synthase PF00926.19 KEZ39502.1 - 1.2e-78 263.1 0.0 1.3e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase NYN PF01936.18 KEZ39504.1 - 0.0024 18.4 0.0 0.0046 17.5 0.0 1.4 1 0 0 1 1 1 1 NYN domain zf-Nse PF11789.8 KEZ39505.1 - 1e-22 79.7 0.4 2.1e-22 78.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KEZ39505.1 - 3.8e-05 23.6 0.1 6.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEZ39505.1 - 0.0075 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 KEZ39505.1 - 0.0085 15.8 0.2 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF2509 PF10713.9 KEZ39505.1 - 0.066 13.3 0.3 0.15 12.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2509) FUSC PF04632.12 KEZ39505.1 - 2.5 6.6 4.0 3.5 6.1 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LMBR1 PF04791.16 KEZ39505.1 - 7.9 5.3 5.5 10 4.9 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3433 PF11915.8 KEZ39506.1 - 4.7e-31 107.1 11.1 2.6e-17 63.1 4.6 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF1146 PF06612.11 KEZ39506.1 - 0.0055 16.7 0.3 0.0055 16.7 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1146) CrgA PF06781.12 KEZ39506.1 - 0.15 12.1 0.7 7.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Cell division protein CrgA Complex1_LYR PF05347.15 KEZ39507.1 - 4.9e-12 45.7 0.1 1.2e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEZ39507.1 - 0.00094 19.9 2.7 0.0021 18.8 0.1 2.6 2 1 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KEZ39507.1 - 0.1 13.2 0.6 0.54 10.9 0.1 2.3 2 1 1 3 3 3 0 Complex1_LYR-like UvrC_HhH_N PF08459.11 KEZ39507.1 - 0.12 12.3 0.4 0.25 11.3 0.2 1.6 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal bZIP_1 PF00170.21 KEZ39508.1 - 7.8e-07 29.1 2.6 1.5e-06 28.2 2.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor RNase_H2-Ydr279 PF09468.10 KEZ39508.1 - 0.088 13.0 0.7 0.15 12.3 0.7 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Glyco_hydro_7 PF00840.20 KEZ39509.1 - 1.1e-151 505.5 4.4 1.4e-151 505.2 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Asp PF00026.23 KEZ39510.1 - 0.0041 16.6 0.0 0.038 13.4 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic aspartyl protease MAP17 PF15807.5 KEZ39510.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 adh_short PF00106.25 KEZ39511.1 - 8.4e-43 146.1 1.8 1.1e-42 145.7 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ39511.1 - 3.3e-32 111.9 0.4 4.4e-32 111.5 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KEZ39511.1 - 0.00028 20.4 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KEZ39511.1 - 0.00065 19.6 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KEZ39511.1 - 0.0018 18.6 0.3 0.0044 17.3 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain ADH_zinc_N PF00107.26 KEZ39511.1 - 0.1 12.6 0.5 0.23 11.5 0.5 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 KEZ39511.1 - 0.16 11.4 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tim17 PF02466.19 KEZ39513.1 - 1.6e-32 112.2 8.0 2.2e-32 111.7 8.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family APH PF01636.23 KEZ39514.1 - 2.2e-08 34.3 0.0 8.3e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_M20 PF01546.28 KEZ39515.1 - 2.3e-21 76.5 0.0 7.2e-21 74.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KEZ39515.1 - 1.6e-14 54.0 7.5 0.016 16.1 0.0 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39515.1 - 0.00029 21.1 0.1 1.2 9.4 0.0 4.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain M20_dimer PF07687.14 KEZ39515.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEZ39515.1 - 0.0023 17.6 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Ge1_WD40 PF16529.5 KEZ39515.1 - 0.012 14.6 0.0 0.078 11.9 0.1 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SARAF PF06682.12 KEZ39515.1 - 0.095 12.3 1.5 0.15 11.7 1.5 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Methyltransf_23 PF13489.6 KEZ39516.1 - 3.9e-14 52.8 0.0 5.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39516.1 - 0.0015 19.2 0.0 0.0058 17.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39516.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39516.1 - 0.015 16.0 0.0 0.034 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RuvA_C PF07499.13 KEZ39516.1 - 0.036 14.5 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain FtsJ PF01728.19 KEZ39517.1 - 1.9e-62 210.5 0.0 2.6e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.26 KEZ39518.1 - 1.1e-16 60.8 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KEZ39518.1 - 0.029 14.7 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain Band_7 PF01145.25 KEZ39519.1 - 1.2e-31 110.1 0.6 2.2e-31 109.3 0.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KEZ39519.1 - 4.9e-23 80.9 0.3 1.3e-22 79.6 0.3 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KEZ39519.1 - 0.02 14.2 0.3 0.028 13.7 0.3 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein GSH-S_N PF02951.14 KEZ39519.1 - 0.099 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain DUF3562 PF12085.8 KEZ39519.1 - 0.17 11.5 0.8 26 4.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) DCB PF16213.5 KEZ39520.1 - 3.1e-47 160.5 5.9 7.2e-46 156.1 5.7 2.8 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KEZ39520.1 - 3.7e-41 140.7 2.4 8.6e-41 139.5 0.1 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KEZ39520.1 - 4.8e-29 101.1 3.4 3e-19 68.7 1.0 3.3 3 0 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KEZ39520.1 - 1.9e-05 24.4 0.4 0.0043 16.9 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Mus7 PF09462.10 KEZ39520.1 - 0.061 12.2 2.0 1 8.1 0.0 3.2 4 0 0 4 4 4 0 Mus7/MMS22 family Velvet PF11754.8 KEZ39521.1 - 9.1e-39 133.9 5.5 5.2e-31 108.5 1.0 3.4 2 1 2 4 4 4 2 Velvet factor Peptidase_M4 PF01447.18 KEZ39522.1 - 5.3e-26 91.9 2.0 8.5e-26 91.2 2.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.15 KEZ39522.1 - 7.8e-25 87.7 1.0 1.6e-19 70.4 0.0 3.0 2 1 1 3 3 3 2 Thermolysin metallopeptidase, alpha-helical domain PLN_propep PF16485.5 KEZ39522.1 - 1.8e-14 53.1 1.2 2.7e-08 33.4 0.2 2.4 2 0 0 2 2 2 2 Protealysin propeptide MCLC PF05934.11 KEZ39523.1 - 0.29 9.8 7.9 0.31 9.7 7.9 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Mucin PF01456.17 KEZ39523.1 - 1.1 9.3 17.6 1.3 9.0 17.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein BLM10_mid PF16507.5 KEZ39524.1 - 6.3e-198 658.7 0.0 1.2e-197 657.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KEZ39524.1 - 1.3e-29 101.9 0.0 5.2e-29 100.0 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KEZ39524.1 - 3.4e-19 68.9 0.3 1e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal Cutinase PF01083.22 KEZ39525.1 - 2.8e-53 180.5 6.3 3.3e-53 180.3 6.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KEZ39525.1 - 6e-07 29.3 0.1 8.7e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 KEZ39525.1 - 0.0055 16.4 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.11 KEZ39525.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Complex1_51K PF01512.17 KEZ39526.1 - 5.1e-46 156.3 0.0 7.8e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KEZ39526.1 - 4.9e-29 100.2 1.3 7e-29 99.7 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KEZ39526.1 - 1.5e-09 37.6 0.0 3.9e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 SLBB domain PEX11 PF05648.14 KEZ39527.1 - 8.9e-27 94.0 0.0 3.8e-26 91.9 0.0 1.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) stn_TNFRSF12A PF12191.8 KEZ39527.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Rab5ip PF07019.12 KEZ39527.1 - 0.064 13.9 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) ATP-synt_E PF05680.12 KEZ39527.1 - 5.2 7.5 10.1 59 4.1 10.1 2.2 1 1 0 1 1 1 0 ATP synthase E chain CUE PF02845.16 KEZ39528.1 - 0.018 14.7 0.0 0.054 13.2 0.0 1.8 2 0 0 2 2 2 0 CUE domain Smr PF01713.21 KEZ39528.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Smr domain MAGI_u5 PF16666.5 KEZ39528.1 - 2 8.6 10.4 0.1 12.8 2.7 2.4 2 1 0 2 2 2 0 Unstructured region on MAGI GMC_oxred_N PF00732.19 KEZ39529.1 - 1.4e-56 192.0 0.0 1.8e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39529.1 - 3.2e-27 95.8 0.2 5.8e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ39529.1 - 0.00013 21.2 0.0 0.1 11.7 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 KEZ39529.1 - 0.00016 21.0 0.8 0.013 14.7 0.1 3.1 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 KEZ39529.1 - 0.005 16.1 0.0 0.016 14.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ39529.1 - 0.0066 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ39529.1 - 0.0089 16.2 0.2 0.028 14.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ39529.1 - 0.074 12.6 0.2 0.69 9.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase APH PF01636.23 KEZ39530.1 - 3.9e-11 43.3 0.2 3e-10 40.4 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ39530.1 - 3.3e-05 23.6 0.0 5.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KEZ39530.1 - 0.085 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PRKCSH-like PF12999.7 KEZ39532.1 - 7.2e-41 139.9 7.9 2.4e-23 82.8 0.7 3.0 2 1 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KEZ39532.1 - 6.5e-32 110.4 0.1 1.7e-31 109.0 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KEZ39532.1 - 8e-10 39.6 0.8 2.1e-09 38.3 0.8 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KEZ39532.1 - 0.00012 22.0 0.4 0.00022 21.2 0.4 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 DFF-C PF09033.10 KEZ39532.1 - 0.01 15.8 3.2 0.039 13.8 3.2 2.0 1 1 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Cep57_MT_bd PF06657.13 KEZ39532.1 - 0.042 14.3 4.3 0.1 13.1 3.1 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ish1 PF10281.9 KEZ39532.1 - 0.058 13.7 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Fib_alpha PF08702.10 KEZ39532.1 - 0.14 12.3 3.0 3.5 7.8 0.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mod_r PF07200.13 KEZ39532.1 - 0.22 11.6 11.2 15 5.7 10.0 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Takusan PF04822.13 KEZ39532.1 - 0.62 10.0 2.5 2.1 8.3 2.5 1.8 1 0 0 1 1 1 0 Takusan DUF4407 PF14362.6 KEZ39532.1 - 6.7 6.0 11.4 15 4.9 8.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAT PF02259.23 KEZ39533.1 - 3.8e-128 427.6 3.3 9e-128 426.3 3.3 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KEZ39533.1 - 2.9e-74 250.0 0.1 5.7e-74 249.1 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KEZ39533.1 - 3.7e-74 248.0 7.5 1.1e-70 236.8 1.4 5.2 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KEZ39533.1 - 1e-45 154.2 0.4 1.6e-44 150.3 0.0 3.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KEZ39533.1 - 1.3e-13 49.9 22.9 0.00067 19.7 0.1 12.1 12 0 0 12 12 12 3 HEAT repeat FATC PF02260.20 KEZ39533.1 - 4.6e-13 48.7 0.1 1.6e-12 47.0 0.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KEZ39533.1 - 2.2e-10 40.8 22.3 0.017 15.5 0.3 9.7 9 2 2 11 11 10 3 HEAT repeats HEAT_EZ PF13513.6 KEZ39533.1 - 1.6e-09 38.1 16.2 1.3e-05 25.5 0.1 10.4 9 2 2 11 11 10 2 HEAT-like repeat Cnd1 PF12717.7 KEZ39533.1 - 1.5e-05 25.1 9.0 0.22 11.6 0.0 7.1 4 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Macscav_rec PF03523.13 KEZ39533.1 - 0.044 13.7 0.2 0.15 11.9 0.2 2.0 1 0 0 1 1 1 0 Macrophage scavenger receptor VirDNA-topo-I_N PF09266.10 KEZ39533.1 - 0.14 12.3 0.0 0.48 10.6 0.0 1.9 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal ANAPC3 PF12895.7 KEZ39533.1 - 0.17 12.1 5.6 1 9.6 0.1 4.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Dopey_N PF04118.14 KEZ39533.1 - 0.26 10.4 4.3 1.4 8.0 0.4 3.3 3 0 0 3 3 3 0 Dopey, N-terminal TPR_7 PF13176.6 KEZ39533.1 - 2.1 8.6 7.1 4.9 7.4 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Sec7_N PF12783.7 KEZ39533.1 - 4.7 7.1 11.7 19 5.2 1.4 5.0 5 2 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Pex24p PF06398.11 KEZ39535.1 - 8.6e-95 317.8 0.0 1.1e-94 317.5 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3306 PF11748.8 KEZ39535.1 - 1.2 10.0 5.3 0.79 10.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) COesterase PF00135.28 KEZ39536.1 - 7.6e-90 302.2 0.0 8.9e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ39536.1 - 6.4e-07 29.4 0.1 2.9e-06 27.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ39536.1 - 6.8e-05 22.4 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 KEZ39536.1 - 0.014 14.5 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) AcetylCoA_hyd_C PF13336.6 KEZ39536.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain SNF2_N PF00176.23 KEZ39538.1 - 6.7e-23 81.0 0.0 1.1e-20 73.6 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ39538.1 - 3.6e-11 43.4 0.0 7.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ39538.1 - 0.00084 19.1 0.2 0.0064 16.3 0.1 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KEZ39538.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEZ39538.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase COesterase PF00135.28 KEZ39539.1 - 4.8e-65 220.4 0.0 1.1e-64 219.2 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ39539.1 - 6.3e-09 36.0 0.0 1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEZ39539.1 - 0.0032 16.4 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Pyr_redox_2 PF07992.14 KEZ39540.1 - 1.4e-13 50.7 0.1 1.9e-10 40.5 0.1 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ39540.1 - 4.7e-05 23.4 0.0 0.00054 20.0 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KEZ39540.1 - 5.2e-05 23.0 0.4 0.0027 17.4 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KEZ39540.1 - 0.0018 17.2 0.3 0.0034 16.3 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KEZ39540.1 - 0.0088 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ39540.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KEZ39540.1 - 0.021 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Malic_M PF03949.15 KEZ39540.1 - 0.053 12.8 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEZ39540.1 - 0.072 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KEZ39540.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 KEZ39540.1 - 0.18 10.9 1.7 0.53 9.3 1.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KEZ39540.1 - 0.22 12.1 0.2 1 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ39540.1 - 2.2 7.5 4.0 16 4.7 3.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1996 PF09362.10 KEZ39541.1 - 3.7e-78 262.8 2.8 4.4e-78 262.5 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 KEZ39542.1 - 1e-74 251.4 2.4 1.3e-74 251.1 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ferric_reduct PF01794.19 KEZ39544.1 - 2.1e-22 79.6 15.4 5e-22 78.3 15.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEZ39544.1 - 9.2e-10 38.9 0.0 9.6e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEZ39544.1 - 4.5e-08 33.2 0.1 2.6e-07 30.7 0.1 2.1 1 1 0 1 1 1 1 FAD-binding domain AftA_C PF12249.8 KEZ39546.1 - 0.093 12.4 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Fungal_trans PF04082.18 KEZ39547.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SnoaL PF07366.12 KEZ39548.1 - 0.0025 17.6 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase Stimulus_sens_1 PF13756.6 KEZ39548.1 - 0.081 13.5 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Stimulus-sensing domain SnoaL_2 PF12680.7 KEZ39548.1 - 0.085 13.5 0.1 0.2 12.3 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like domain Methyltransf_23 PF13489.6 KEZ39549.1 - 7.6e-21 74.6 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39549.1 - 1.7e-13 51.0 0.0 3.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39549.1 - 8.2e-13 48.4 0.1 1.6e-11 44.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39549.1 - 7.4e-12 45.8 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39549.1 - 2.9e-09 37.6 0.0 1.5e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ39549.1 - 0.00013 21.4 0.0 0.00045 19.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KEZ39549.1 - 0.00015 21.3 0.0 0.00037 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KEZ39549.1 - 0.00091 18.6 0.0 0.0024 17.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KEZ39549.1 - 0.0024 18.0 0.0 0.0062 16.7 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KEZ39549.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEZ39549.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KEZ39549.1 - 0.037 13.3 0.0 0.12 11.7 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KEZ39549.1 - 0.056 12.8 0.0 0.63 9.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4246 PF14033.6 KEZ39550.1 - 1.5e-167 558.3 0.0 2e-167 557.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KEZ39550.1 - 0.0087 16.5 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KEZ39550.1 - 0.032 15.1 0.0 0.08 13.8 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KEZ39551.1 - 1.8e-27 96.2 35.1 1.8e-27 96.2 35.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MASE2 PF05230.11 KEZ39551.1 - 2.3 8.4 10.7 0.22 11.6 4.4 2.6 2 0 0 2 2 2 0 MASE2 domain Tannase PF07519.11 KEZ39552.1 - 3.1e-89 300.1 0.4 3.5e-89 299.9 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KEZ39552.1 - 0.00013 21.6 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEZ39552.1 - 0.069 12.4 0.0 9 5.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 CLIP_SPH_mas PF18398.1 KEZ39552.1 - 0.07 13.5 0.2 0.19 12.1 0.2 1.7 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade Polysacc_deac_1 PF01522.21 KEZ39553.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Porin_7 PF16956.5 KEZ39553.1 - 0.089 12.4 0.5 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Putative general bacterial porin ComA PF02679.15 KEZ39554.1 - 6.4e-92 307.4 0.0 7.3e-92 307.2 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) HMGL-like PF00682.19 KEZ39554.1 - 0.0045 16.6 0.0 3 7.3 0.0 2.8 3 0 0 3 3 3 2 HMGL-like Sugar_tr PF00083.24 KEZ39555.1 - 1.7e-101 340.3 12.7 2e-101 340.1 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39555.1 - 3.7e-24 85.3 25.3 1.5e-18 66.9 1.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ39555.1 - 0.001 18.5 4.9 0.003 16.9 1.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 KEZ39555.1 - 0.0017 16.7 0.4 0.0038 15.6 0.4 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 KEZ39556.1 - 1.4e-08 34.0 0.1 3.8e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 KEZ39557.1 - 2.5e-63 214.5 0.0 3.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KEZ39558.1 - 1e-23 84.0 1.1 1.3e-17 63.9 0.3 3.0 1 1 1 2 2 2 2 Aldo/keto reductase family Cyclase PF04199.13 KEZ39559.1 - 1.2e-18 67.6 0.0 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Corona_3 PF04694.12 KEZ39559.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Coronavirus ORF3 protein Sensor PF13796.6 KEZ39560.1 - 0.016 15.3 7.1 0.053 13.6 1.2 2.3 2 0 0 2 2 2 0 Putative sensor DIOX_N PF14226.6 KEZ39561.1 - 5.6e-32 111.0 0.0 8.2e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ39561.1 - 6.4e-24 84.4 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.6 KEZ39562.1 - 1.6e-11 44.3 0.0 2.1e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39562.1 - 3.1e-08 34.1 0.0 5.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39562.1 - 6.2e-07 30.1 0.0 9.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39562.1 - 7.6e-07 29.8 0.0 1.3e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39562.1 - 2.6e-05 24.1 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KEZ39562.1 - 0.0057 16.4 0.0 0.0077 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 KEZ39562.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KEZ39562.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 KEZ39562.1 - 0.22 11.3 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 KEZ39563.1 - 1.2e-18 67.5 0.0 1.8e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39563.1 - 1.5e-14 54.4 0.0 3.7e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39563.1 - 6e-12 46.0 0.0 1.4e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39563.1 - 1.2e-10 42.0 0.0 4.9e-10 40.0 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39563.1 - 1.9e-10 40.7 0.0 2.5e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ39563.1 - 2.2e-05 23.9 0.0 0.00016 21.1 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ39563.1 - 0.0001 22.4 0.0 0.00023 21.3 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KEZ39563.1 - 0.00013 21.5 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KEZ39563.1 - 0.00069 19.2 0.0 0.0021 17.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ39563.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KEZ39563.1 - 0.03 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KEZ39563.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 KEZ39563.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_15 PF09445.10 KEZ39563.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 KEZ39563.1 - 0.22 11.2 0.0 0.34 10.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Pkinase PF00069.25 KEZ39564.1 - 1e-16 61.1 0.0 3.3e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39564.1 - 1.9e-08 33.9 0.0 0.00081 18.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Methyltransf_23 PF13489.6 KEZ39564.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CFEM PF05730.11 KEZ39566.1 - 1.8e-07 31.1 6.0 3.7e-07 30.2 6.0 1.5 1 0 0 1 1 1 1 CFEM domain DUF737 PF05300.11 KEZ39566.1 - 0.017 15.5 3.3 0.03 14.7 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Podoplanin PF05808.11 KEZ39566.1 - 0.038 14.1 1.0 0.093 12.8 0.0 1.9 2 0 0 2 2 2 0 Podoplanin Phage_GP20 PF06810.11 KEZ39566.1 - 0.065 13.0 2.3 0.091 12.6 2.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Mod_r PF07200.13 KEZ39566.1 - 0.14 12.3 3.9 0.21 11.7 3.9 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MtrF PF09472.10 KEZ39566.1 - 0.72 9.3 2.6 1.3 8.5 2.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3306 PF11748.8 KEZ39566.1 - 2.3 9.1 7.4 5.7 7.8 2.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) Fungal_trans PF04082.18 KEZ39567.1 - 3.3e-22 78.8 0.0 5.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 KEZ39568.1 - 6.6e-143 476.6 0.6 1.3e-76 258.0 0.2 3.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Dirigent PF03018.14 KEZ39568.1 - 0.026 14.3 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 Dirigent-like protein Aa_trans PF01490.18 KEZ39569.1 - 5.8e-26 91.1 37.1 8.9e-25 87.2 37.1 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4231 PF14015.6 KEZ39569.1 - 1.4 9.4 0.0 1.4 9.4 0.0 4.2 4 1 2 6 6 6 0 Protein of unknown function (DUF4231) ADH_N PF08240.12 KEZ39570.1 - 1.1e-31 108.9 2.5 2.4e-31 107.9 2.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ39570.1 - 1.1e-13 51.3 0.0 1.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ39570.1 - 1.2e-07 31.4 0.4 1.1e-06 28.3 0.4 2.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KEZ39570.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Transketolase_N PF00456.21 KEZ39571.1 - 5.2e-122 407.0 0.0 6.9e-122 406.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KEZ39571.1 - 7.3e-41 139.8 0.0 1.2e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ39571.1 - 3.3e-06 27.0 0.0 9.4e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KEZ39571.1 - 7.9e-06 25.3 0.0 2.3e-05 23.7 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KEZ39571.1 - 0.031 13.2 0.1 0.047 12.6 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Fungal_trans_2 PF11951.8 KEZ39572.1 - 5.7e-16 58.3 1.9 1.2e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KEZ39573.1 - 7.7e-46 156.6 0.0 9.7e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.28 KEZ39574.1 - 2.8e-92 310.2 0.0 3.4e-92 309.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ39574.1 - 1.4e-06 28.3 0.1 7.5e-06 26.0 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Sugar_tr PF00083.24 KEZ39575.1 - 1.6e-82 277.8 18.5 1.9e-82 277.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39575.1 - 5.2e-16 58.5 20.2 5.2e-16 58.5 20.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily EF-hand_4 PF12763.7 KEZ39576.1 - 1.5e-14 53.8 0.0 2.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KEZ39576.1 - 0.0033 16.8 2.1 0.025 14.1 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 KEZ39576.1 - 0.02 14.8 0.8 0.69 10.0 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 KEZ39576.1 - 0.093 13.2 0.0 0.4 11.2 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain pair Polysacc_deac_1 PF01522.21 KEZ39577.1 - 6.4e-30 103.6 0.0 8.7e-30 103.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KEZ39577.1 - 1.4e-06 28.7 17.7 2.4e-06 27.9 17.7 1.4 1 0 0 1 1 1 1 Chitin recognition protein Creatininase PF02633.14 KEZ39577.1 - 0.061 12.8 0.3 0.15 11.5 0.1 1.7 2 0 0 2 2 2 0 Creatinine amidohydrolase DUF533 PF04391.12 KEZ39577.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Glyco_hydro_57 PF03065.15 KEZ39577.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 PsbX PF06596.11 KEZ39577.1 - 0.54 10.3 2.0 1.3 9.1 2.0 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) NAD_binding_8 PF13450.6 KEZ39580.1 - 9e-12 45.0 0.0 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ39580.1 - 2e-07 30.5 1.0 4e-07 29.5 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEZ39580.1 - 2.9e-07 30.2 0.1 4e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KEZ39580.1 - 2.4e-06 27.4 0.5 4.6e-06 26.4 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ39580.1 - 2.2e-05 23.4 0.2 3.3e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KEZ39580.1 - 5.9e-05 23.5 0.1 0.00014 22.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ39580.1 - 0.00052 19.3 0.3 0.001 18.4 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ39580.1 - 0.00064 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ39580.1 - 0.0021 17.4 0.0 0.0056 15.9 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KEZ39580.1 - 0.0024 17.3 0.0 0.021 14.1 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KEZ39580.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KEZ39580.1 - 0.093 11.8 0.3 0.15 11.1 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 KEZ39582.1 - 2.6e-32 112.2 0.1 1.6e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ39582.1 - 2.4e-30 105.5 0.0 3.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Peptidase_S8 PF00082.22 KEZ39583.1 - 1.4e-31 109.9 12.9 3.2e-31 108.7 12.8 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEZ39583.1 - 2.6e-07 31.2 0.0 1.1e-06 29.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_23 PF13489.6 KEZ39585.1 - 6.6e-23 81.3 0.0 9.6e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39585.1 - 1.1e-12 48.5 0.0 3.1e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39585.1 - 1.8e-10 41.3 0.0 3.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39585.1 - 1.3e-08 34.8 0.0 1.9e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39585.1 - 1.7e-06 28.7 0.0 1.4e-05 25.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ39585.1 - 1.8e-05 24.2 0.0 0.00019 20.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ39585.1 - 0.00024 21.2 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KEZ39585.1 - 0.00084 18.8 0.0 0.0027 17.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KEZ39585.1 - 0.0036 16.9 0.0 0.0072 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ39585.1 - 0.021 14.1 0.0 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 KEZ39585.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 KEZ39585.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 KEZ39585.1 - 0.16 11.7 0.0 0.97 9.1 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fe-ADH PF00465.19 KEZ39586.1 - 2.8e-75 253.4 0.5 3.2e-75 253.2 0.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KEZ39586.1 - 3.3e-14 53.2 0.2 4.7e-14 52.7 0.2 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1677 PF07911.13 KEZ39586.1 - 0.19 12.2 0.0 0.49 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Dioxygenase_C PF00775.21 KEZ39587.1 - 9.4e-40 136.0 0.0 1.6e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEZ39587.1 - 1.9e-32 111.0 0.0 2.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEZ39587.1 - 0.001 19.3 0.0 0.0033 17.7 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain CoA_transf_3 PF02515.17 KEZ39588.1 - 9.7e-26 90.7 0.4 2.9e-14 53.0 0.0 4.2 3 2 1 4 4 4 3 CoA-transferase family III DUF3583 PF12126.8 KEZ39588.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) p450 PF00067.22 KEZ39589.1 - 3e-58 197.7 0.0 1.8e-56 191.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 CSTF_C PF14304.6 KEZ39589.1 - 0.0067 16.0 0.9 0.012 15.2 0.9 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal FAD_binding_3 PF01494.19 KEZ39590.1 - 9.1e-48 163.3 0.0 1.2e-47 162.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Carboxyl_trans PF01039.22 KEZ39591.1 - 2e-100 336.8 0.0 2.9e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KEZ39591.1 - 3.2e-65 219.6 0.0 5.5e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KEZ39591.1 - 3.8e-28 97.7 0.0 7.4e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KEZ39591.1 - 6.3e-28 97.5 0.0 2.4e-27 95.7 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KEZ39591.1 - 5.5e-11 42.1 4.8 4.6e-10 39.2 4.3 2.3 1 1 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 KEZ39591.1 - 1.7e-09 37.5 0.1 3.5e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEZ39591.1 - 5.7e-09 35.8 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KEZ39591.1 - 3.8e-06 27.0 0.0 6.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KEZ39591.1 - 2e-05 24.3 0.0 0.0055 16.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.11 KEZ39591.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain AMP-binding PF00501.28 KEZ39592.1 - 2.1e-74 250.6 0.1 3.8e-41 141.1 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ39592.1 - 2.6e-12 47.5 0.0 1.2e-11 45.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 KEZ39593.1 - 3e-40 138.1 0.0 5.2e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ39593.1 - 9.1e-23 81.3 0.0 1.2e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 KEZ39593.1 - 4.5e-21 75.6 0.3 9.7e-14 51.5 0.0 2.3 1 1 1 2 2 2 2 HMGL-like Fungal_trans_2 PF11951.8 KEZ39594.1 - 0.00029 19.8 0.1 0.003 16.4 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 KEZ39597.1 - 5.4e-23 81.7 0.0 1.2e-22 80.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ39597.1 - 9.8e-13 48.5 0.1 1.8e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ39597.1 - 0.0007 19.3 0.1 0.036 13.7 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KEZ39597.1 - 0.0052 15.7 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase K_oxygenase PF13434.6 KEZ39597.1 - 0.0061 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ39597.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KEZ39597.1 - 0.035 14.5 0.0 0.34 11.4 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding Trp_ring PF18669.1 KEZ39597.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain ApbA PF02558.16 KEZ39597.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KEZ39597.1 - 0.095 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 KEZ39597.1 - 0.19 10.8 0.0 0.53 9.3 0.0 1.7 1 1 1 2 2 2 0 Lycopene cyclase protein DUF4743 PF15916.5 KEZ39598.1 - 2.4e-10 40.4 0.0 3.9e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) DNase_NucA_NucB PF14040.6 KEZ39600.1 - 4.6e-06 27.0 2.0 1e-05 25.9 0.4 2.3 2 1 1 3 3 3 1 Deoxyribonuclease NucA/NucB CPG4 PF15481.6 KEZ39600.1 - 0.031 14.9 6.6 1.7 9.3 0.4 2.3 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 DUF3079 PF11278.8 KEZ39600.1 - 0.093 12.6 1.9 2.1 8.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) tRNA-synt_1g PF09334.11 KEZ39601.1 - 4.7e-95 318.6 0.1 1.3e-93 313.9 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KEZ39601.1 - 1.8e-22 79.4 3.1 3.4e-09 35.5 0.2 3.7 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.7 KEZ39601.1 - 2.1e-17 64.1 0.1 1.4e-16 61.4 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.19 KEZ39601.1 - 2.5e-10 40.2 0.0 2.3e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Acetyltransf_8 PF13523.6 KEZ39601.1 - 0.024 14.3 0.1 0.35 10.6 0.0 2.4 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DUF4160 PF13711.6 KEZ39601.1 - 0.068 13.5 0.0 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) DUF1754 PF08555.10 KEZ39602.1 - 3.2e-11 43.9 15.4 4.7e-11 43.3 15.4 1.2 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 KEZ39602.1 - 0.061 12.7 16.3 0.071 12.5 16.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Adaptin_binding PF10199.9 KEZ39602.1 - 0.33 11.6 11.7 0.57 10.8 11.7 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RRN3 PF05327.11 KEZ39602.1 - 5 5.5 7.0 6 5.3 7.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 KEZ39603.1 - 0.47 10.4 13.9 0.65 9.9 13.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KEZ39603.1 - 5.6 6.0 28.2 7.4 5.7 28.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KEZ39603.1 - 9 6.1 26.7 16 5.3 26.7 1.3 1 0 0 1 1 1 0 SPX domain DUF3619 PF12279.8 KEZ39604.1 - 0.039 14.3 1.6 0.22 11.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) VanZ PF04892.12 KEZ39604.1 - 0.45 11.2 2.0 0.54 10.9 0.6 1.8 2 0 0 2 2 2 0 VanZ like family MatE PF01554.18 KEZ39604.1 - 1.1 8.8 6.5 2.4 7.8 0.3 3.2 3 0 0 3 3 3 0 MatE ORC2 PF04084.14 KEZ39605.1 - 2.1e-117 391.8 0.0 2.6e-117 391.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SEEEED PF14797.6 KEZ39605.1 - 0.9 9.7 12.7 4.7 7.4 6.1 2.4 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex PGP_phosphatase PF09419.10 KEZ39606.1 - 3.8e-62 208.8 0.0 5.2e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KEZ39606.1 - 3.1e-06 27.1 0.0 6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like CutC PF03932.14 KEZ39607.1 - 1.1e-33 116.4 0.0 2e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 CutC family TGT PF01702.18 KEZ39608.1 - 8.2e-59 199.5 0.0 1e-58 199.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CENP-I PF07778.11 KEZ39609.1 - 1.1e-14 54.1 0.0 4.9e-10 38.7 0.0 3.1 2 1 0 2 2 2 2 Mis6 ADH_zinc_N_2 PF13602.6 KEZ39610.1 - 7.2e-19 69.2 0.0 1.6e-18 68.1 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ39610.1 - 3.6e-10 39.9 0.1 6.9e-10 39.0 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ39610.1 - 0.0001 22.1 0.0 0.015 15.2 0.0 3.1 2 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KEZ39610.1 - 0.00021 21.1 0.1 0.00037 20.3 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.20 KEZ39610.1 - 0.0078 16.3 0.1 0.017 15.2 0.0 1.5 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus AMP-binding PF00501.28 KEZ39610.1 - 0.023 13.3 0.1 0.41 9.2 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme Peripla_BP_4 PF13407.6 KEZ39610.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.5 2 0 0 2 2 2 0 Periplasmic binding protein domain CAS_CSE1 PF03378.15 KEZ39611.1 - 8.6e-163 541.9 0.1 3.6e-162 539.9 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KEZ39611.1 - 6.2e-153 509.0 1.6 1.1e-152 508.2 1.6 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KEZ39611.1 - 9.8e-14 51.0 0.7 6.2e-13 48.5 0.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KEZ39611.1 - 0.034 14.2 0.3 1.2 9.2 0.0 3.6 3 1 0 3 3 3 0 Exportin 1-like protein adh_short PF00106.25 KEZ39612.1 - 6.8e-24 84.4 0.1 9.1e-22 77.5 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ39612.1 - 6.3e-14 52.1 0.1 6.1e-12 45.6 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ39612.1 - 5.2e-05 23.2 0.4 0.00012 22.0 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEZ39612.1 - 0.0084 15.6 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KEZ39612.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_transf_3 PF02515.17 KEZ39613.1 - 1.7e-68 231.4 0.0 2.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF2484 PF10658.9 KEZ39613.1 - 0.061 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) Dynamin_M PF01031.20 KEZ39614.1 - 2.7e-101 338.5 0.0 5e-101 337.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KEZ39614.1 - 1.3e-56 191.3 0.0 2.2e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KEZ39614.1 - 8.9e-30 102.7 3.3 8.9e-30 102.7 3.3 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KEZ39614.1 - 0.00014 21.9 0.1 0.0014 18.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KEZ39614.1 - 0.052 13.3 0.8 2.5 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 KEZ39615.1 - 5.1e-07 30.3 10.6 0.046 14.6 0.2 5.8 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39615.1 - 0.0012 19.1 1.5 6.9 7.1 0.0 4.4 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 KEZ39615.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain Cytochrom_D1 PF02239.16 KEZ39615.1 - 0.16 10.4 0.0 0.35 9.3 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain CENP-B_dimeris PF09026.10 KEZ39616.1 - 0.11 12.9 3.5 0.22 11.9 3.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_E_B PF04042.16 KEZ39617.1 - 1e-49 168.8 0.0 1.3e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KEZ39617.1 - 2.2e-39 134.5 0.0 3.3e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Elong-fact-P_C PF09285.11 KEZ39617.1 - 0.013 15.2 0.4 0.059 13.1 0.2 2.0 2 0 0 2 2 2 0 Elongation factor P, C-terminal PALP PF00291.25 KEZ39618.1 - 1.7e-59 201.7 0.1 2e-59 201.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CENP-S PF15630.6 KEZ39620.1 - 1.5e-30 105.3 0.2 2.4e-30 104.7 0.2 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KEZ39620.1 - 3.7e-10 39.9 0.1 4.3e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KEZ39620.1 - 0.00093 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 KEZ39620.1 - 0.016 15.2 0.1 0.02 14.9 0.1 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Imm71 PF15602.6 KEZ39620.1 - 0.063 13.3 0.5 4.9 7.2 0.1 2.1 1 1 1 2 2 2 0 Immunity protein 71 TAF PF02969.17 KEZ39620.1 - 0.086 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) AA_permease_2 PF13520.6 KEZ39621.1 - 4.8e-37 127.8 35.2 6.7e-37 127.3 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ39621.1 - 8.4e-12 44.4 27.7 8.4e-12 44.4 27.7 1.4 1 1 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 KEZ39621.1 - 0.0022 16.9 8.5 0.0063 15.4 1.4 3.0 3 0 0 3 3 3 2 Spore germination protein Ribosomal_L4 PF00573.22 KEZ39623.1 - 8.7e-37 126.7 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KEZ39623.1 - 3.6e-27 94.2 2.9 7.5e-27 93.2 2.9 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.21 KEZ39624.1 - 2e-13 50.3 0.0 9.5e-12 44.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Lipase_3 PF01764.25 KEZ39626.1 - 1e-29 103.2 0.0 1.6e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KEZ39626.1 - 4.1e-12 45.9 0.0 8.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.7 KEZ39626.1 - 0.021 15.4 0.1 0.029 15.0 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family EAR PF07897.11 KEZ39626.1 - 0.14 11.8 0.0 0.52 10.0 0.0 2.0 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression DUF2974 PF11187.8 KEZ39626.1 - 0.15 11.5 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LRR_4 PF12799.7 KEZ39627.1 - 2.8e-06 27.6 2.8 0.36 11.3 0.6 5.2 5 1 1 6 6 5 1 Leucine Rich repeats (2 copies) YL1 PF05764.13 KEZ39627.1 - 0.00034 20.8 4.8 0.00055 20.1 4.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein LRR_8 PF13855.6 KEZ39627.1 - 0.024 14.4 0.2 1.4 8.7 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat Myc_N PF01056.18 KEZ39627.1 - 0.042 13.7 4.1 0.064 13.2 4.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region LRR_6 PF13516.6 KEZ39627.1 - 0.086 12.9 10.2 16 5.8 0.0 5.6 6 0 0 6 6 5 0 Leucine Rich repeat TF_Zn_Ribbon PF08271.12 KEZ39627.1 - 0.089 12.3 0.3 0.31 10.6 0.3 2.0 1 0 0 1 1 1 0 TFIIB zinc-binding CDC45 PF02724.14 KEZ39627.1 - 0.12 10.7 6.0 0.15 10.3 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 KEZ39627.1 - 0.16 12.1 8.3 0.28 11.3 8.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) VGLL4 PF15245.6 KEZ39627.1 - 0.22 11.6 3.1 0.39 10.8 3.1 1.4 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 NOA36 PF06524.12 KEZ39627.1 - 0.43 9.9 6.0 0.12 11.6 2.5 1.8 2 0 0 2 2 2 0 NOA36 protein PTPRCAP PF15713.5 KEZ39627.1 - 0.83 9.9 8.4 1.5 9.1 8.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SRP-alpha_N PF04086.13 KEZ39627.1 - 1 9.2 10.8 1.7 8.5 10.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 KEZ39627.1 - 2.8 7.7 6.2 2.8 7.7 5.1 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SNF2_N PF00176.23 KEZ39628.1 - 8e-49 166.2 0.0 3.5e-43 147.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ39628.1 - 1.5e-14 54.2 0.0 7.3e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ39628.1 - 1.2e-06 28.7 0.0 3.6e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 KEZ39628.1 - 4.5e-06 26.4 11.8 4.5e-06 26.4 11.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ39628.1 - 1.1e-05 25.2 13.5 1.1e-05 25.2 13.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEZ39628.1 - 0.00054 20.2 13.9 0.00054 20.2 13.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEZ39628.1 - 0.0011 18.8 12.1 0.0011 18.8 12.1 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KEZ39628.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Zn_Tnp_IS91 PF14319.6 KEZ39628.1 - 0.017 15.2 8.2 0.1 12.6 1.5 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Prok-RING_4 PF14447.6 KEZ39628.1 - 0.07 13.0 13.4 0.18 11.7 13.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KEZ39628.1 - 0.25 11.2 4.1 0.63 9.9 4.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Tim17 PF02466.19 KEZ39629.1 - 4.2e-38 130.1 10.6 5.3e-38 129.8 10.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KEZ39629.1 - 0.016 15.1 0.4 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF5518 PF17647.1 KEZ39629.1 - 0.21 11.8 6.6 0.27 11.4 1.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5518) AMPK1_CBM PF16561.5 KEZ39630.1 - 3.5e-26 91.2 0.0 7.7e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 KEZ39630.1 - 4.3e-23 81.4 3.4 4.3e-23 81.4 3.4 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain SelP_N PF04592.14 KEZ39630.1 - 1.5 8.2 6.1 4.1 6.7 6.1 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MAP65_ASE1 PF03999.12 KEZ39630.1 - 5.9 5.5 9.8 10 4.7 9.8 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) EPL1 PF10513.9 KEZ39631.1 - 1.5e-20 74.1 2.1 1.5e-20 74.1 2.1 2.6 3 0 0 3 3 3 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 KEZ39632.1 - 2.9e-20 70.2 12.4 3.9e-08 32.3 1.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KEZ39632.1 - 2.1e-18 66.5 5.9 2.2e-14 53.6 1.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEZ39632.1 - 4.2e-14 51.2 5.9 6.7e-05 22.5 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KEZ39632.1 - 5.3e-13 47.8 8.0 3e-07 29.6 0.7 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KEZ39632.1 - 3.3e-11 42.8 9.9 1e-05 25.3 0.8 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KEZ39632.1 - 1.5e-06 28.1 6.1 0.013 15.5 0.7 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KEZ39632.1 - 0.00036 20.8 0.2 0.00086 19.6 0.2 1.8 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KEZ39632.1 - 0.0064 16.8 0.0 0.35 11.2 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KEZ39632.1 - 0.083 13.1 4.2 0.26 11.5 2.7 2.5 1 1 1 2 2 2 0 Dockerin type I domain Ribosomal_S9 PF00380.19 KEZ39634.1 - 5.8e-41 139.8 0.4 9.6e-41 139.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 KEZ39635.1 - 3e-42 143.0 0.1 5.1e-42 142.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KEZ39635.1 - 1.5e-16 60.4 0.0 3.8e-16 59.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEZ39635.1 - 3.1e-10 39.9 0.1 9.4e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEZ39635.1 - 3.6e-09 36.8 0.0 2.2e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEZ39635.1 - 9.6e-05 22.5 0.1 0.00035 20.7 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEZ39635.1 - 0.0025 18.2 0.0 0.0066 16.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPP5 PF08321.12 KEZ39636.1 - 1.1e-33 115.4 0.2 1.3e-32 112.0 0.0 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KEZ39636.1 - 1.4e-31 110.6 0.1 2.1e-31 110.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KEZ39636.1 - 2.3e-18 65.1 5.2 4.1e-07 29.5 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ39636.1 - 2.3e-15 55.4 3.1 3.9e-05 23.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ39636.1 - 4.1e-12 45.6 3.3 0.00024 20.7 0.0 3.4 3 0 0 3 3 3 3 TPR repeat TPR_9 PF13371.6 KEZ39636.1 - 7e-07 29.3 0.0 0.02 15.0 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ39636.1 - 1.1e-06 28.6 0.7 0.028 14.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ39636.1 - 2.3e-06 27.4 4.9 0.016 15.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ39636.1 - 0.00083 20.0 0.0 2.3 8.9 0.0 2.8 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ39636.1 - 0.0052 17.3 0.1 0.29 11.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ39636.1 - 0.013 16.0 0.2 0.49 10.9 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ39636.1 - 0.026 15.3 0.1 2.5 9.2 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ39636.1 - 0.15 12.3 0.1 14 6.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt4 PF06093.13 KEZ39637.1 - 1.2e-32 111.8 0.1 1.5e-32 111.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 KEZ39637.1 - 0.081 12.9 0.3 0.18 11.8 0.1 1.6 1 1 1 2 2 2 0 Coronavirus gene 5 protein Kin17_mid PF10357.9 KEZ39638.1 - 5.3e-50 168.6 1.4 5.3e-50 168.6 1.4 2.5 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KEZ39638.1 - 0.0011 19.2 3.3 0.0022 18.2 3.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ39638.1 - 0.007 16.7 5.0 0.015 15.7 5.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type TFIID_NTD2 PF04494.15 KEZ39638.1 - 0.036 14.3 0.2 0.079 13.2 0.2 1.6 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain zf-C2H2_2 PF12756.7 KEZ39638.1 - 0.048 14.0 0.4 0.048 14.0 0.4 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SlyX PF04102.12 KEZ39639.1 - 0.0055 17.3 2.0 0.0055 17.3 2.0 1.8 2 0 0 2 2 2 1 SlyX DUF16 PF01519.16 KEZ39639.1 - 0.36 11.3 1.5 0.57 10.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 PBP PF01161.20 KEZ39640.1 - 4.4e-18 65.9 0.0 6.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein USP7_ICP0_bdg PF12436.8 KEZ39641.1 - 2.3e-79 266.1 0.0 2.3e-77 259.6 0.0 2.4 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KEZ39641.1 - 2.7e-74 249.3 2.3 9.4e-74 247.6 1.0 2.5 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 KEZ39641.1 - 4.9e-47 160.6 1.4 9.7e-47 159.6 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ39641.1 - 1.9e-20 73.7 0.3 4.1e-20 72.6 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KEZ39641.1 - 2.1e-09 37.5 0.1 9.3e-09 35.4 0.1 2.2 1 1 1 2 2 2 1 MATH domain YukD PF08817.10 KEZ39641.1 - 0.087 13.5 0.0 4.6 8.0 0.0 3.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.9 KEZ39642.1 - 1.9e-44 151.4 0.1 3.8e-44 150.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEZ39642.1 - 0.0002 21.8 0.0 0.0018 18.8 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Baculo_IE-1 PF05290.11 KEZ39642.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Septin PF00735.18 KEZ39643.1 - 6.4e-115 383.3 0.3 9.4e-115 382.7 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KEZ39643.1 - 2e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEZ39643.1 - 5.8e-06 26.0 3.9 7.7e-05 22.3 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEZ39643.1 - 7.5e-06 26.0 1.8 3.2e-05 23.9 0.0 2.5 3 0 0 3 3 2 1 RsgA GTPase AAA_22 PF13401.6 KEZ39643.1 - 0.0016 18.7 0.6 0.0043 17.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 KEZ39643.1 - 0.0025 17.3 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KEZ39643.1 - 0.0035 17.6 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KEZ39643.1 - 0.0079 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KEZ39643.1 - 0.009 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Casc1_N PF15927.5 KEZ39643.1 - 0.013 15.2 10.7 0.033 13.9 10.7 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 KEZ39643.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 KEZ39643.1 - 0.019 14.6 0.5 0.062 12.9 0.5 1.9 2 1 0 2 2 2 0 Ras family KAP_NTPase PF07693.14 KEZ39643.1 - 0.039 13.2 0.0 0.05 12.8 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 KEZ39643.1 - 0.041 14.3 1.0 0.086 13.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KEZ39643.1 - 0.049 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KEZ39643.1 - 0.057 13.9 0.2 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 KEZ39643.1 - 0.065 12.3 0.3 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KEZ39643.1 - 0.08 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 KEZ39643.1 - 0.1 12.2 0.1 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KEZ39643.1 - 0.13 12.0 0.4 8.3 6.2 0.1 2.6 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KEZ39643.1 - 0.14 12.6 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase FOXP-CC PF16159.5 KEZ39643.1 - 0.39 11.4 5.7 0.1 13.3 1.1 2.5 2 1 0 2 2 1 0 FOXP coiled-coil domain Dynamin_N PF00350.23 KEZ39643.1 - 0.59 10.2 6.9 4.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 KEZ39643.1 - 1.2 9.7 6.0 7.8 7.1 0.2 3.2 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_11 PF13086.6 KEZ39643.1 - 1.5 8.5 7.0 17 5.1 3.6 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 KEZ39643.1 - 6.3 7.0 11.4 11 6.2 5.1 3.3 2 1 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.32 KEZ39644.1 - 2.9e-38 129.2 29.8 7.5e-09 36.1 0.1 12.1 14 0 0 14 14 13 6 WD domain, G-beta repeat Utp12 PF04003.12 KEZ39644.1 - 2.7e-24 85.5 0.0 4.2e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KEZ39644.1 - 2.4e-23 82.2 0.0 0.00092 19.5 0.0 10.1 4 2 5 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ39644.1 - 7.6e-10 38.3 1.4 0.79 8.6 0.0 6.1 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEZ39644.1 - 1e-07 32.0 1.8 0.02 14.8 0.0 5.8 6 1 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KEZ39644.1 - 4e-06 25.2 0.0 0.00012 20.3 0.0 2.3 2 0 0 2 2 2 1 IKI3 family WD40_like PF17005.5 KEZ39644.1 - 7.3e-05 22.2 0.0 0.52 9.6 0.0 4.1 4 0 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 KEZ39644.1 - 0.00029 19.6 9.1 0.86 8.2 0.3 4.6 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 KEZ39644.1 - 0.00034 20.1 0.1 1.2 8.4 0.0 4.2 4 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KEZ39644.1 - 0.033 13.1 0.0 6.5 5.6 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KEZ39644.1 - 0.054 12.0 0.0 4 5.9 0.0 3.0 2 1 0 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 KEZ39644.1 - 0.12 12.9 3.4 52 4.5 0.0 5.1 5 0 0 5 5 5 0 PQQ-like domain Questin_oxidase PF14027.6 KEZ39645.1 - 2.6e-73 247.5 0.7 3.2e-73 247.2 0.7 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAP PF00956.18 KEZ39646.1 - 2.1e-27 96.0 1.4 7.9e-27 94.1 1.4 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) PBP1_TM PF14812.6 KEZ39646.1 - 0.13 12.6 7.2 4.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SURF2 PF05477.11 KEZ39646.1 - 0.31 10.7 2.1 0.66 9.6 2.1 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Baculo_PEP_C PF04513.12 KEZ39647.1 - 1.9 8.5 8.9 5.8 7.0 4.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tape_meas_lam_C PF09718.10 KEZ39647.1 - 2.9 8.1 7.8 1 9.6 0.5 3.0 2 2 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Pkinase PF00069.25 KEZ39648.1 - 3.9e-63 213.3 0.0 4.6e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39648.1 - 9e-29 100.5 0.0 1.2e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEZ39648.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KEZ39648.1 - 0.028 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KEZ39648.1 - 0.065 12.5 0.0 0.18 11.1 0.0 1.7 1 1 0 1 1 1 0 Kinase-like FAT PF02259.23 KEZ39649.1 - 7e-72 242.5 2.4 2.1e-71 241.0 2.4 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KEZ39649.1 - 1.1e-32 113.9 0.5 2.7e-32 112.5 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KEZ39649.1 - 2.3e-08 33.7 0.6 6.9e-08 32.2 0.6 1.9 1 0 0 1 1 1 1 FATC domain DUF445 PF04286.12 KEZ39649.1 - 0.00011 22.2 1.7 0.026 14.3 0.0 4.1 3 0 0 3 3 3 1 Protein of unknown function (DUF445) TPR_2 PF07719.17 KEZ39649.1 - 0.16 12.2 2.6 4.7 7.6 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FANCI_S3 PF14677.6 KEZ39649.1 - 0.16 11.6 1.7 3.3 7.4 0.1 3.6 4 0 0 4 4 4 0 FANCI solenoid 3 Hid1 PF12722.7 KEZ39649.1 - 0.84 7.7 8.5 1.5 6.9 8.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pol_alpha_B_N PF08418.10 KEZ39649.1 - 1.1 9.1 17.9 0.22 11.5 12.1 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal FANCI_S2 PF14676.6 KEZ39649.1 - 1.7 8.9 5.5 4.1 7.7 0.1 3.8 4 0 0 4 4 4 0 FANCI solenoid 2 GGACT PF06094.12 KEZ39650.1 - 9.5e-22 77.9 0.1 1.2e-21 77.5 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF3433 PF11915.8 KEZ39651.1 - 7.4e-37 125.7 3.6 6.8e-18 64.9 0.1 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) POT1 PF02765.17 KEZ39652.1 - 7.4e-16 58.3 0.0 1.5e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Fungal_trans PF04082.18 KEZ39653.1 - 1.2e-31 109.7 0.5 2e-31 109.0 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ39653.1 - 1e-07 32.0 9.6 1.9e-07 31.1 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin-6_N PF09177.11 KEZ39654.1 - 7.9e-25 87.3 1.8 1.6e-24 86.3 0.3 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KEZ39654.1 - 0.0011 19.0 0.7 0.0029 17.6 0.7 1.8 1 0 0 1 1 1 1 SNARE domain LPP PF04728.13 KEZ39654.1 - 0.0093 16.3 1.2 0.096 13.1 0.4 2.7 3 0 0 3 3 3 1 Lipoprotein leucine-zipper FlaC_arch PF05377.11 KEZ39654.1 - 0.011 16.1 1.2 12 6.3 0.0 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KEZ39654.1 - 0.014 15.9 0.9 6.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 KEZ39654.1 - 0.014 15.8 0.9 0.021 15.3 0.9 1.3 1 0 0 1 1 1 0 Fez1 MscS_porin PF12795.7 KEZ39654.1 - 0.018 14.6 1.5 0.018 14.6 1.5 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Cob_adeno_trans PF01923.18 KEZ39654.1 - 0.087 13.0 0.2 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase MbeD_MobD PF04899.12 KEZ39654.1 - 0.12 12.4 2.4 1.8 8.8 0.1 2.6 2 1 0 2 2 2 0 MbeD/MobD like ATG16 PF08614.11 KEZ39654.1 - 0.14 12.3 6.4 3.5 7.8 0.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KEZ39654.1 - 0.6 8.9 3.6 0.65 8.8 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DASH_Duo1 PF08651.10 KEZ39654.1 - 0.71 9.7 2.7 1.6 8.5 0.3 2.7 3 1 1 4 4 4 0 DASH complex subunit Duo1 SlyX PF04102.12 KEZ39654.1 - 3.3 8.4 13.2 0.34 11.6 0.2 4.1 3 2 0 3 3 3 0 SlyX CorA PF01544.18 KEZ39654.1 - 4.8 6.4 8.0 3.9 6.7 0.1 3.1 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein ACT_7 PF13840.6 KEZ39655.1 - 5.6e-21 74.1 1.0 1.8e-16 59.7 0.2 2.5 2 0 0 2 2 2 2 ACT domain HC2 PF07382.11 KEZ39656.1 - 0.13 12.3 91.2 0.043 13.9 30.6 4.9 1 1 3 4 4 4 0 Histone H1-like nucleoprotein HC2 Porin_3 PF01459.22 KEZ39657.1 - 6e-83 278.4 1.4 7e-83 278.2 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 KEZ39658.1 - 5.4e-61 205.7 0.0 7.7e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KEZ39658.1 - 3.3e-23 82.4 0.2 1.5e-22 80.3 0.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KEZ39658.1 - 0.0035 17.5 0.1 0.069 13.3 0.0 2.7 2 1 0 3 3 3 1 AAA domain ZnuA PF01297.17 KEZ39658.1 - 0.052 12.9 0.1 0.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic UCH_1 PF13423.6 KEZ39659.1 - 8.5e-32 111.0 0.0 8.6e-31 107.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 KEZ39659.1 - 1e-15 57.9 0.0 2e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.21 KEZ39660.1 - 4.4e-25 87.7 0.0 6.8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KEZ39660.1 - 2e-05 24.9 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Actin PF00022.19 KEZ39661.1 - 5.8e-151 502.7 0.0 2.1e-150 500.9 0.0 1.7 1 1 0 1 1 1 1 Actin RF-1 PF00472.20 KEZ39662.1 - 2e-24 85.7 2.7 4.2e-24 84.7 2.7 1.5 1 0 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 KEZ39663.1 - 7.9e-19 67.0 8.1 1.1e-18 66.6 8.1 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like WD40 PF00400.32 KEZ39664.1 - 2.4e-31 107.3 17.3 6.5e-06 26.8 0.3 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39664.1 - 2.1e-09 37.6 0.0 2.3 8.6 0.0 7.2 5 4 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ39664.1 - 0.042 12.8 0.0 5.1 5.9 0.0 3.4 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mub_B2 PF17966.1 KEZ39664.1 - 0.09 13.5 1.7 0.17 12.6 0.1 2.4 2 0 0 2 2 2 0 Mub B2-like domain Mito_carr PF00153.27 KEZ39665.1 - 3.7e-59 196.7 3.5 3.4e-20 71.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 KEZ39666.1 - 0.0017 18.7 4.5 0.0049 17.2 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ39666.1 - 0.26 12.2 3.0 0.73 10.8 3.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Urm1 PF09138.11 KEZ39667.1 - 8.6e-36 122.2 0.0 9.9e-36 122.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KEZ39667.1 - 1.8e-05 25.3 0.0 2.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ThiS family RRM_1 PF00076.22 KEZ39668.1 - 2.1e-34 117.1 0.0 3.9e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ39668.1 - 0.0099 15.5 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KEZ39668.1 - 0.015 14.9 0.3 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KEZ39668.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KEZ39668.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif MIF4G_like PF09088.11 KEZ39669.1 - 3.8e-88 294.3 0.0 2.6e-87 291.5 0.0 2.1 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 KEZ39669.1 - 4e-67 226.5 0.0 7.6e-67 225.6 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KEZ39669.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain Pkinase PF00069.25 KEZ39670.1 - 3.1e-56 190.7 0.0 3.2e-51 174.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39670.1 - 4.7e-17 62.1 0.0 7.2e-15 55.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEZ39670.1 - 9.5e-06 25.1 0.0 5.3e-05 22.7 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 KEZ39670.1 - 0.00097 19.1 0.0 0.0041 17.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ39670.1 - 0.086 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1229 PF06797.11 KEZ39670.1 - 0.097 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Kdo PF06293.14 KEZ39670.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF410 PF04190.13 KEZ39671.1 - 1.2e-91 307.0 0.0 1.5e-91 306.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) tRNA-synt_1 PF00133.22 KEZ39672.1 - 5e-50 170.4 0.1 5.8e-10 38.1 0.0 6.1 3 1 3 6 6 6 6 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KEZ39672.1 - 2.6e-40 137.9 0.0 6.3e-40 136.7 0.0 1.6 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KEZ39672.1 - 1.2e-30 106.6 0.0 9.1e-22 77.3 0.0 4.3 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEZ39672.1 - 3.5e-13 49.8 0.0 6.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KEZ39672.1 - 0.00032 20.1 0.0 0.23 10.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Pox_Ag35 PF03286.14 KEZ39673.1 - 0.74 9.6 9.1 2.2 8.0 9.0 1.8 1 1 0 1 1 1 0 Pox virus Ag35 surface protein FXMRP1_C_core PF12235.8 KEZ39673.1 - 0.85 10.3 3.5 0.94 10.1 2.1 1.8 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DUF4551 PF15087.6 KEZ39673.1 - 1.6 7.5 4.5 1.7 7.4 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pneumo_att_G PF05539.11 KEZ39673.1 - 5.4 6.5 12.5 7 6.1 12.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PQ-loop PF04193.14 KEZ39674.1 - 1.2e-18 66.6 3.4 3.8e-13 49.0 1.6 2.5 2 0 0 2 2 2 2 PQ loop repeat SMI1_KNR4 PF09346.10 KEZ39675.1 - 1.8e-31 109.3 0.0 5.7e-31 107.7 0.0 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pkinase PF00069.25 KEZ39676.1 - 4.6e-70 236.0 0.0 6.2e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39676.1 - 4.8e-50 170.2 0.0 8e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ39676.1 - 3.2e-06 26.2 0.0 6.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEZ39676.1 - 0.00026 20.4 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Transglut_core PF01841.19 KEZ39677.1 - 1.4e-10 41.6 0.1 3.4e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KEZ39677.1 - 9.9e-09 34.8 0.2 2.6e-08 33.4 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ39677.1 - 1e-05 25.0 1.4 5e-05 22.8 0.1 2.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KEZ39677.1 - 0.015 15.1 0.3 0.042 13.7 0.3 1.7 1 0 0 1 1 1 0 Variant SH3 domain CCDC32 PF14989.6 KEZ39677.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing 32 WD40 PF00400.32 KEZ39678.1 - 4.2e-18 65.4 11.8 3.5e-07 30.8 0.4 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 KEZ39678.1 - 1.6e-16 60.5 0.1 2.8e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 KEZ39678.1 - 0.055 13.8 0.1 2 8.8 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Sec8_exocyst PF04048.14 KEZ39679.1 - 2.4e-49 166.9 2.5 6.5e-49 165.5 2.5 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KEZ39679.1 - 2.1e-09 37.1 2.8 4.6e-09 36.0 2.8 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KEZ39679.1 - 0.00033 19.4 5.3 0.00033 19.4 5.3 2.2 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 YcbB PF08664.10 KEZ39679.1 - 0.025 14.6 1.2 0.068 13.2 1.2 1.7 1 0 0 1 1 1 0 YcbB domain Vps51 PF08700.11 KEZ39679.1 - 0.073 13.2 0.5 13 5.9 0.2 3.4 1 1 1 2 2 2 0 Vps51/Vps67 DUF4220 PF13968.6 KEZ39679.1 - 0.085 12.2 0.7 0.22 10.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Sec5 PF15469.6 KEZ39679.1 - 0.32 10.8 5.0 0.14 11.9 2.0 2.0 2 0 0 2 2 2 0 Exocyst complex component Sec5 Swi5 PF07061.11 KEZ39679.1 - 1.1 9.5 6.1 0.15 12.2 0.9 2.4 2 0 0 2 2 2 0 Swi5 4HB_MCP_1 PF12729.7 KEZ39679.1 - 1.6 8.2 4.0 1.4 8.4 0.7 2.7 3 1 0 3 3 3 0 Four helix bundle sensory module for signal transduction Lebercilin PF15619.6 KEZ39679.1 - 4.4 6.9 12.0 0.58 9.8 4.9 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease UPF0220 PF05255.11 KEZ39680.1 - 8.4e-63 210.8 3.0 9.4e-63 210.7 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1689 PF07954.11 KEZ39680.1 - 0.25 11.7 0.5 0.47 10.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) DNA_pol_A_exo1 PF01612.20 KEZ39681.1 - 2.8e-18 66.2 0.0 4.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.32 KEZ39682.1 - 2e-20 72.7 4.7 2e-05 25.2 0.4 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39682.1 - 1.4e-09 38.1 0.1 0.0035 17.6 0.0 5.1 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KEZ39682.1 - 0.013 14.8 0.0 0.27 10.5 0.0 2.6 2 1 1 3 3 3 0 WD40-like domain Nup160 PF11715.8 KEZ39682.1 - 0.027 13.1 0.4 1.6 7.3 0.0 3.2 3 1 0 4 4 4 0 Nucleoporin Nup120/160 PQQ PF01011.21 KEZ39682.1 - 0.047 13.6 0.1 4 7.5 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat Glyco_transf_15 PF01793.16 KEZ39683.1 - 1.5e-114 382.7 6.4 1.8e-114 382.4 6.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 KEZ39684.1 - 1.8e-35 123.1 0.0 2.9e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KEZ39684.1 - 4.3e-29 102.0 0.8 4.3e-29 102.0 0.8 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KEZ39684.1 - 1.8e-06 26.6 0.0 4.8e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 RNA_pol_L_2 PF13656.6 KEZ39685.1 - 1.4e-22 79.3 0.1 1.7e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KEZ39685.1 - 2.9e-06 26.6 0.0 2.6e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 KEZ39685.1 - 0.027 14.7 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal Asparaginase PF00710.20 KEZ39686.1 - 3.4e-58 196.4 0.0 5.2e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KEZ39686.1 - 1.7e-25 89.4 0.0 3.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KEZ39686.1 - 7.7e-17 61.7 0.2 1.9e-09 38.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ39686.1 - 1.2e-08 35.0 0.2 0.00047 20.5 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KEZ39686.1 - 1.7e-07 31.0 0.1 0.003 17.9 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KEZ39686.1 - 2.5e-06 27.9 0.3 0.00081 19.9 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ39686.1 - 9.1e-05 22.7 0.3 0.00088 19.5 0.2 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) ATP-synt_ab PF00006.25 KEZ39687.1 - 1.6e-108 361.3 0.0 2.3e-108 360.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KEZ39687.1 - 1.3e-43 147.7 0.0 2.4e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KEZ39687.1 - 3.8e-16 59.4 1.8 8.3e-16 58.3 1.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KEZ39687.1 - 0.014 14.6 0.1 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Metallophos PF00149.28 KEZ39688.1 - 5.1e-13 50.0 0.0 9e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ39688.1 - 0.14 12.3 0.2 1.4 9.0 0.0 2.4 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain TruB_N PF01509.18 KEZ39690.1 - 5.1e-44 150.2 0.0 1e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KEZ39690.1 - 0.00069 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF2951 PF11166.8 KEZ39690.1 - 0.57 10.4 1.8 1.1 9.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) EXOSC1 PF10447.9 KEZ39691.1 - 3.4e-19 69.4 3.4 2.2e-13 50.8 0.1 2.7 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KEZ39691.1 - 2.9e-09 36.6 1.1 5.7e-09 35.6 1.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 KEZ39691.1 - 0.13 12.6 0.4 0.71 10.3 0.4 2.0 1 1 0 1 1 1 0 S1 RNA binding domain ERG2_Sigma1R PF04622.12 KEZ39692.1 - 1.8e-96 321.5 0.1 2.2e-96 321.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 KEZ39692.1 - 0.018 15.0 0.2 0.71 9.9 0.0 2.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Fcf1 PF04900.12 KEZ39693.1 - 1.7e-33 115.0 0.1 5.4e-33 113.3 0.0 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KEZ39693.1 - 4.1e-11 43.2 0.3 1.1e-10 41.9 0.0 1.7 2 0 0 2 2 2 1 PIN like domain ABC_membrane PF00664.23 KEZ39694.1 - 4.2e-50 170.9 39.0 3.6e-34 118.7 19.4 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ39694.1 - 1.2e-48 165.1 0.0 1.1e-26 94.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.23 KEZ39694.1 - 4.5e-06 26.7 1.1 0.054 13.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 KEZ39694.1 - 5.3e-06 26.0 0.6 1.2 8.5 0.0 3.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ39694.1 - 6.9e-06 25.7 0.3 0.035 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEZ39694.1 - 2.3e-05 23.8 0.0 0.0023 17.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KEZ39694.1 - 2.7e-05 24.6 0.0 0.27 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ39694.1 - 7.1e-05 22.8 0.4 0.053 13.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KEZ39694.1 - 0.00061 20.4 0.2 2.1 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KEZ39694.1 - 0.0022 18.1 3.8 0.14 12.3 0.5 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 KEZ39694.1 - 0.0064 16.3 2.9 1.9 8.2 0.2 3.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEZ39694.1 - 0.0065 16.2 2.0 1.8 8.2 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KEZ39694.1 - 0.009 16.3 0.8 7.5 6.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KEZ39694.1 - 0.012 15.6 4.4 0.081 13.0 0.4 2.6 2 0 0 2 2 2 0 Dynamin family AAA_7 PF12775.7 KEZ39694.1 - 0.021 14.3 0.2 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KEZ39694.1 - 0.028 14.2 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 KEZ39694.1 - 0.028 13.3 0.8 2.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Ploopntkinase3 PF18751.1 KEZ39694.1 - 0.031 14.2 0.2 11 5.9 0.0 2.6 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_15 PF13175.6 KEZ39694.1 - 0.035 13.8 0.5 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KEZ39694.1 - 0.035 13.1 0.7 1.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KEZ39694.1 - 0.04 14.1 0.1 9.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KEZ39694.1 - 0.11 11.9 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.7 KEZ39694.1 - 0.13 11.1 0.6 1.5 7.7 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_27 PF13514.6 KEZ39694.1 - 0.15 11.6 0.1 1.6 8.3 0.0 2.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KEZ39694.1 - 0.17 12.3 0.2 47 4.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.6 KEZ39694.1 - 0.22 12.1 0.7 7.9 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KEZ39694.1 - 0.57 9.9 1.6 19 4.9 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 KEZ39694.1 - 0.6 10.3 3.4 0.82 9.9 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF1018 PF06252.12 KEZ39695.1 - 0.065 14.2 0.4 0.21 12.6 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) zf-C2H2_4 PF13894.6 KEZ39696.1 - 0.85 10.6 3.5 1.5 9.9 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger GDA1_CD39 PF01150.17 KEZ39697.1 - 3.7e-103 345.4 0.0 4.7e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KEZ39697.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family AAA_lid_2 PF17863.1 KEZ39698.1 - 1.8e-05 24.5 1.0 4e-05 23.4 1.0 1.6 1 0 0 1 1 1 1 AAA lid domain UreE_C PF05194.12 KEZ39698.1 - 0.01 16.3 0.9 0.027 15.0 0.9 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain AAA_3 PF07726.11 KEZ39698.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 KEZ39699.1 - 1.6e-45 154.6 0.1 1.9e-45 154.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ39699.1 - 6.3e-20 71.6 0.0 9.9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ39699.1 - 8.6e-09 35.1 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEZ39699.1 - 0.00034 20.2 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEZ39699.1 - 0.015 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region EamA PF00892.20 KEZ39700.1 - 1.7e-08 34.7 36.5 6e-06 26.5 6.0 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 KEZ39700.1 - 2.9e-07 30.2 0.5 2.9e-07 30.2 0.5 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3955) SLC35F PF06027.12 KEZ39700.1 - 0.00011 21.8 8.8 0.00027 20.6 8.8 1.7 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 KEZ39700.1 - 0.00026 20.4 5.5 0.00026 20.4 5.5 2.5 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 KEZ39700.1 - 0.0089 15.3 16.7 0.0065 15.7 13.7 1.9 2 0 0 2 2 2 1 UAA transporter family Brr6_like_C_C PF10104.9 KEZ39700.1 - 0.4 10.4 0.0 0.4 10.4 0.0 2.8 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain WD40 PF00400.32 KEZ39701.1 - 1.2e-13 51.3 11.5 0.0088 16.9 0.2 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39701.1 - 1.3e-09 38.2 0.0 0.0096 16.2 0.0 5.6 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Spb1_C PF07780.12 KEZ39702.1 - 1.7e-89 299.0 24.0 1.7e-89 299.0 24.0 3.5 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KEZ39702.1 - 1.3e-56 191.6 0.0 2.4e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KEZ39702.1 - 3.4e-51 173.3 11.0 3.4e-51 173.3 11.0 5.0 3 1 2 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KEZ39702.1 - 0.05 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cupin_8 PF13621.6 KEZ39703.1 - 1.9e-65 221.1 0.0 2.5e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KEZ39703.1 - 1.4e-05 24.7 0.0 0.0028 17.2 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 KEZ39703.1 - 0.072 13.5 0.1 1 9.8 0.0 2.5 3 0 0 3 3 3 0 JmjC domain, hydroxylase Macoilin PF09726.9 KEZ39704.1 - 0.13 10.8 10.9 0.17 10.4 10.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF4202 PF13875.6 KEZ39705.1 - 2e-60 203.9 0.9 1.7e-59 200.9 0.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4202) N-SET PF11764.8 KEZ39707.1 - 1.2e-52 178.5 0.1 1.2e-52 178.5 0.1 3.2 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KEZ39707.1 - 1.2e-25 88.9 1.8 2.1e-25 88.1 0.9 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 KEZ39707.1 - 6e-20 72.3 0.2 6e-20 72.3 0.2 4.2 4 2 0 4 4 4 1 SET domain RRM_1 PF00076.22 KEZ39707.1 - 0.13 12.1 0.2 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tropomyosin_1 PF12718.7 KEZ39709.1 - 1.1e-52 178.0 29.2 1.3e-52 177.8 29.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KEZ39709.1 - 5.9e-08 32.4 29.0 5e-05 22.8 14.9 2.7 1 1 1 2 2 2 2 Tropomyosin Spc7 PF08317.11 KEZ39709.1 - 0.00015 20.8 29.9 0.01 14.7 15.4 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF724 PF05266.14 KEZ39709.1 - 0.00025 20.9 21.4 0.017 15.0 8.6 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF724) ERM PF00769.19 KEZ39709.1 - 0.00027 20.9 29.8 0.015 15.1 16.4 2.0 2 0 0 2 2 2 2 Ezrin/radixin/moesin family ATG16 PF08614.11 KEZ39709.1 - 0.0003 21.1 28.1 0.052 13.8 13.5 2.4 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 KEZ39709.1 - 0.00037 20.9 30.6 0.11 12.9 15.9 2.9 2 2 0 2 2 2 2 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 KEZ39709.1 - 0.00044 20.6 30.9 0.013 15.8 14.6 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 KEZ39709.1 - 0.00072 19.7 27.9 0.014 15.5 6.8 3.0 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KEZ39709.1 - 0.00077 20.0 35.0 0.0072 16.9 20.7 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 KEZ39709.1 - 0.00082 19.4 29.1 0.0013 18.8 5.6 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 KEZ39709.1 - 0.00093 18.9 29.1 0.0032 17.2 15.0 2.4 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Cep57_CLD_2 PF14197.6 KEZ39709.1 - 0.0012 18.9 26.7 0.27 11.4 5.2 3.8 1 1 1 3 3 3 2 Centrosome localisation domain of PPC89 TACC_C PF05010.14 KEZ39709.1 - 0.0013 18.5 22.1 0.019 14.8 11.0 2.2 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Taxilin PF09728.9 KEZ39709.1 - 0.0016 17.7 27.8 0.1 11.7 7.3 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein MAD PF05557.13 KEZ39709.1 - 0.0018 16.8 6.2 0.0018 16.8 6.2 2.1 1 1 1 2 2 2 1 Mitotic checkpoint protein T3SSipB PF16535.5 KEZ39709.1 - 0.0033 17.9 16.8 0.44 11.0 4.2 2.9 1 1 1 2 2 2 2 Type III cell invasion protein SipB KLRAQ PF10205.9 KEZ39709.1 - 0.0038 17.4 5.2 0.0038 17.4 5.2 3.0 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.11 KEZ39709.1 - 0.0039 17.5 18.5 0.16 12.4 3.5 4.1 3 1 1 4 4 4 3 Flagella accessory protein C (FlaC) CEP63 PF17045.5 KEZ39709.1 - 0.0087 16.0 21.8 0.012 15.5 21.8 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa GAS PF13851.6 KEZ39709.1 - 0.0088 15.4 29.4 0.17 11.2 13.7 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KEZ39709.1 - 0.0091 15.3 24.9 0.086 12.1 10.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KEZ39709.1 - 0.0098 16.0 29.3 0.019 15.1 7.6 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 KEZ39709.1 - 0.01 16.4 16.2 0.15 12.7 6.6 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cep57_MT_bd PF06657.13 KEZ39709.1 - 0.011 16.1 22.1 0.083 13.4 2.2 3.4 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 NPV_P10 PF05531.12 KEZ39709.1 - 0.014 15.8 11.0 0.16 12.5 4.6 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KEZ39709.1 - 0.019 15.0 13.6 0.31 11.1 2.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KEZ39709.1 - 0.019 15.2 19.1 4.5 7.6 1.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Laminin_II PF06009.12 KEZ39709.1 - 0.021 14.8 18.7 0.038 14.0 5.7 2.5 1 1 1 2 2 2 0 Laminin Domain II Surfac_D-trimer PF09006.11 KEZ39709.1 - 0.022 14.6 3.1 0.038 13.9 0.0 2.8 4 0 0 4 4 1 0 Lung surfactant protein D coiled-coil trimerisation BST2 PF16716.5 KEZ39709.1 - 0.022 15.3 23.6 0.53 10.9 6.5 2.7 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 KEZ39709.1 - 0.035 14.3 28.5 0.085 13.1 16.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 EzrA PF06160.12 KEZ39709.1 - 0.039 12.1 21.9 0.21 9.7 9.5 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Fez1 PF06818.15 KEZ39709.1 - 0.04 14.4 23.9 0.11 12.9 24.0 1.5 1 1 0 1 1 1 0 Fez1 bZIP_1 PF00170.21 KEZ39709.1 - 0.041 14.0 29.1 0.4 10.8 0.6 4.6 2 2 1 4 4 4 0 bZIP transcription factor DUF4482 PF14818.6 KEZ39709.1 - 0.05 14.5 5.7 0.05 14.5 5.7 2.9 1 1 2 3 3 2 0 Domain of unknown function (DUF4482) DUF745 PF05335.13 KEZ39709.1 - 0.059 13.1 18.2 0.08 12.7 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TMF_TATA_bd PF12325.8 KEZ39709.1 - 0.066 13.4 23.2 1 9.6 13.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding KASH_CCD PF14662.6 KEZ39709.1 - 0.073 12.9 28.0 0.078 12.8 18.3 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Alanine_zipper PF11839.8 KEZ39709.1 - 0.073 13.4 10.7 1.5 9.2 0.9 3.6 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein HOOK PF05622.12 KEZ39709.1 - 0.074 11.2 26.4 0.22 9.6 26.4 1.7 1 1 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 KEZ39709.1 - 0.09 12.8 34.3 0.18 11.8 8.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SOGA PF11365.8 KEZ39709.1 - 0.092 13.9 23.1 2.2 9.5 9.7 3.4 1 1 2 3 3 3 0 Protein SOGA HAP1_N PF04849.13 KEZ39709.1 - 0.12 11.6 27.1 0.25 10.5 27.1 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4407 PF14362.6 KEZ39709.1 - 0.17 11.2 20.9 1.5 8.2 21.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KELK PF15796.5 KEZ39709.1 - 0.18 12.3 29.0 0.43 11.1 4.8 3.6 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec34 PF04136.15 KEZ39709.1 - 0.2 11.5 15.6 0.22 11.4 4.5 2.4 1 1 1 2 2 2 0 Sec34-like family CLZ PF16526.5 KEZ39709.1 - 0.21 12.0 23.9 0.73 10.2 2.0 3.8 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BRE1 PF08647.11 KEZ39709.1 - 0.22 11.6 28.2 1.6 8.9 12.9 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.9 KEZ39709.1 - 0.25 11.6 21.6 2.1 8.7 2.6 3.6 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Transketolase_N PF00456.21 KEZ39709.1 - 0.27 10.1 4.8 0.35 9.8 4.8 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain HMMR_C PF15908.5 KEZ39709.1 - 0.3 11.4 17.4 0.11 12.7 4.6 2.9 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal CENP-K PF11802.8 KEZ39709.1 - 0.4 10.2 19.3 0.15 11.6 4.8 2.2 1 1 1 2 2 2 0 Centromere-associated protein K Fib_alpha PF08702.10 KEZ39709.1 - 0.4 10.9 16.4 1 9.5 3.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KEZ39709.1 - 0.4 10.1 27.4 0.86 9.0 27.4 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal KxDL PF10241.9 KEZ39709.1 - 0.43 10.9 17.6 1.1 9.5 0.9 3.9 1 1 3 4 4 4 0 Uncharacterized conserved protein WXG100 PF06013.12 KEZ39709.1 - 0.44 10.8 13.8 2.9 8.2 0.2 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG TMF_DNA_bd PF12329.8 KEZ39709.1 - 0.47 10.5 30.2 0.3 11.1 9.3 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CASP_C PF08172.12 KEZ39709.1 - 0.48 9.7 19.6 0.21 10.9 1.9 2.1 1 1 1 2 2 2 0 CASP C terminal DUF3584 PF12128.8 KEZ39709.1 - 0.49 7.8 24.0 0.76 7.2 24.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4763 PF15960.5 KEZ39709.1 - 0.51 9.6 18.6 0.51 9.6 4.8 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4763) Rootletin PF15035.6 KEZ39709.1 - 0.57 10.2 27.8 0.14 12.2 6.1 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion LPP PF04728.13 KEZ39709.1 - 0.57 10.6 13.4 7.7 7.0 1.5 4.1 2 1 1 3 3 2 0 Lipoprotein leucine-zipper DUF812 PF05667.11 KEZ39709.1 - 0.58 9.0 24.6 0.98 8.2 24.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1843 PF08898.10 KEZ39709.1 - 0.59 10.7 10.6 2.9 8.5 0.4 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF1843) CALCOCO1 PF07888.11 KEZ39709.1 - 0.61 8.9 27.7 2.6 6.8 12.1 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fmp27_WPPW PF10359.9 KEZ39709.1 - 0.66 8.8 22.5 0.058 12.2 9.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.22 KEZ39709.1 - 0.67 10.2 25.3 2.7 8.3 3.9 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4201 PF13870.6 KEZ39709.1 - 0.68 9.6 23.4 3 7.5 7.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) PI3K_P85_iSH2 PF16454.5 KEZ39709.1 - 0.71 9.5 24.2 13 5.3 23.7 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain XhlA PF10779.9 KEZ39709.1 - 0.71 10.1 25.5 5.3 7.3 4.6 4.1 1 1 3 4 4 4 0 Haemolysin XhlA GIT_CC PF16559.5 KEZ39709.1 - 0.77 9.7 17.3 1.2 9.1 1.9 4.5 3 3 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lge1 PF11488.8 KEZ39709.1 - 0.81 9.9 18.4 0.93 9.7 1.0 3.9 2 2 1 3 3 3 0 Transcriptional regulatory protein LGE1 HrpB7 PF09486.10 KEZ39709.1 - 1 9.7 16.6 6.3 7.2 1.7 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) ZapB PF06005.12 KEZ39709.1 - 1.1 9.7 37.5 7.7 7.0 14.1 3.7 1 1 2 3 3 3 0 Cell division protein ZapB Cortex-I_coil PF09304.10 KEZ39709.1 - 1.2 9.4 22.6 16 5.7 8.5 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil Vps5 PF09325.10 KEZ39709.1 - 1.4 8.4 20.9 0.35 10.4 12.2 2.4 1 1 2 3 3 3 0 Vps5 C terminal like Nup88 PF10168.9 KEZ39709.1 - 1.4 6.7 19.9 2.4 5.9 19.9 1.4 1 1 0 1 1 1 0 Nuclear pore component Swi5 PF07061.11 KEZ39709.1 - 1.4 9.0 23.3 0.32 11.1 0.9 3.6 1 1 0 2 2 1 0 Swi5 HAUS-augmin3 PF14932.6 KEZ39709.1 - 1.5 8.4 26.0 0.25 10.9 12.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Uds1 PF15456.6 KEZ39709.1 - 1.5 9.0 22.0 5.8 7.1 2.9 2.6 1 1 1 2 2 2 0 Up-regulated During Septation AAA_11 PF13086.6 KEZ39709.1 - 1.6 8.5 12.4 2.1 8.0 12.4 1.2 1 0 0 1 1 1 0 AAA domain DHR10 PF18595.1 KEZ39709.1 - 1.9 8.6 30.9 0.13 12.3 6.6 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 KEZ39709.1 - 1.9 8.9 23.1 25 5.3 10.5 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) She9_MDM33 PF05546.11 KEZ39709.1 - 2 8.2 18.2 4 7.2 9.1 2.1 1 1 1 2 2 2 0 She9 / Mdm33 family DUF948 PF06103.11 KEZ39709.1 - 2 8.7 12.3 13 6.2 3.5 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 KEZ39709.1 - 2.1 7.6 19.0 7.8 5.8 19.0 1.8 1 1 0 1 1 1 0 FAM76 protein Mod_r PF07200.13 KEZ39709.1 - 2.1 8.4 24.5 0.66 10.1 13.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.12 KEZ39709.1 - 2.3 6.7 3.6 2.4 6.6 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc29 PF17082.5 KEZ39709.1 - 2.4 7.9 15.7 4.8 7.0 3.6 2.7 1 1 2 3 3 3 0 Spindle Pole Component 29 TRAF_BIRC3_bd PF16673.5 KEZ39709.1 - 2.5 8.0 14.6 7 6.5 1.4 3.7 2 1 2 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain DUF730 PF05325.11 KEZ39709.1 - 2.6 8.1 15.0 0.95 9.5 1.8 2.9 1 1 2 3 3 2 0 Protein of unknown function (DUF730) DUF4686 PF15742.5 KEZ39709.1 - 3 6.9 30.1 40 3.2 30.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) Atg14 PF10186.9 KEZ39709.1 - 3.2 6.7 20.4 1.7e+02 1.1 20.4 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2730 PF10805.8 KEZ39709.1 - 3.5 7.8 12.8 1.4 9.1 4.0 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) MbeD_MobD PF04899.12 KEZ39709.1 - 3.8 7.7 12.6 5 7.3 0.4 3.1 2 2 2 4 4 3 0 MbeD/MobD like TolA_bind_tri PF16331.5 KEZ39709.1 - 3.8 7.6 23.1 0.27 11.4 2.1 3.8 3 2 1 4 4 4 0 TolA binding protein trimerisation Prefoldin PF02996.17 KEZ39709.1 - 4 7.4 27.4 1.8 8.5 2.0 4.0 1 1 3 4 4 4 0 Prefoldin subunit FapA PF03961.13 KEZ39709.1 - 4.4 5.8 24.1 0.48 9.0 9.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF16 PF01519.16 KEZ39709.1 - 4.6 7.8 21.6 3.2 8.3 6.7 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 TMPIT PF07851.13 KEZ39709.1 - 4.8 6.3 19.9 5.7 6.1 5.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF1515 PF07439.11 KEZ39709.1 - 6.5 6.8 7.8 11 6.1 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) AAA_13 PF13166.6 KEZ39709.1 - 6.7 5.2 21.8 2.1 6.9 5.8 1.8 1 1 0 1 1 1 0 AAA domain SlyX PF04102.12 KEZ39709.1 - 7 7.3 21.3 0.67 10.6 2.2 3.6 2 2 1 3 3 3 0 SlyX Occludin_ELL PF07303.13 KEZ39709.1 - 8 7.3 18.7 1.4e+02 3.3 3.7 3.2 1 1 1 2 2 2 0 Occludin homology domain CHDCT2 PF08074.11 KEZ39709.1 - 8.4 6.5 9.6 1.1 9.4 3.3 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain OmpH PF03938.14 KEZ39709.1 - 8.6 6.7 31.7 34 4.8 18.9 2.6 1 1 1 2 2 1 0 Outer membrane protein (OmpH-like) PRKG1_interact PF15898.5 KEZ39709.1 - 8.9 7.3 26.3 3.3 8.7 13.0 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain COG2 PF06148.11 KEZ39709.1 - 9 6.4 17.3 7.7 6.6 4.0 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Nop25 PF09805.9 KEZ39710.1 - 2.8e-39 134.7 16.4 2.8e-39 134.7 16.4 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) RseA_C PF03873.13 KEZ39710.1 - 2.5 8.4 6.6 28 5.0 6.6 2.7 1 1 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain EIIBC-GUT_N PF03612.14 KEZ39710.1 - 3.3 7.4 14.7 5.2 6.8 4.9 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ATP-synt_S1 PF05827.12 KEZ39711.1 - 0.0045 16.8 0.1 0.0085 15.9 0.1 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Trm112p PF03966.16 KEZ39712.1 - 1.7e-15 57.3 0.1 2.3e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Pro_isomerase PF00160.21 KEZ39713.1 - 1.7e-50 171.4 0.3 2e-50 171.2 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 KEZ39714.1 - 1.4e-15 57.8 0.1 1.4e-13 51.3 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 KEZ39715.1 - 2.8e-101 338.9 0.0 3.5e-101 338.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RhoGAP PF00620.27 KEZ39716.1 - 4.1e-16 59.2 0.1 1.1e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KEZ39716.1 - 7.9e-13 48.3 0.0 1.8e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KEZ39716.1 - 2.5e-07 30.9 0.0 1.3e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 KEZ39716.1 - 0.057 13.1 2.2 0.086 12.5 0.7 2.0 2 0 0 2 2 2 0 BAR domain Adaptin_N PF01602.20 KEZ39717.1 - 3.2e-85 286.7 0.1 5e-85 286.0 0.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEZ39717.1 - 2.1e-07 31.1 0.0 0.00076 19.6 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEZ39717.1 - 0.0053 16.9 0.2 12 6.5 0.0 4.9 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KEZ39717.1 - 0.016 15.6 0.6 0.3 11.5 0.0 3.2 3 1 2 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 KEZ39717.1 - 0.13 12.8 0.9 13 6.4 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat AP3D1 PF06375.11 KEZ39717.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.6 1 1 0 2 2 2 0 AP-3 complex subunit delta-1 TPR_11 PF13414.6 KEZ39719.1 - 6.3e-08 32.2 1.2 0.0039 16.8 0.5 3.7 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 KEZ39719.1 - 2.1e-06 28.1 3.0 0.13 13.2 0.3 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ39719.1 - 8.1e-06 25.6 1.1 0.0074 16.3 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ39719.1 - 1e-05 25.9 0.9 0.00098 19.6 0.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ39719.1 - 1.2e-05 25.8 0.3 0.0093 16.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ39719.1 - 2.9e-05 23.9 1.5 1.2 9.5 0.3 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF627 PF04781.12 KEZ39719.1 - 0.00017 21.6 0.1 0.04 13.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF627) TPR_6 PF13174.6 KEZ39719.1 - 0.00032 21.1 1.5 4.4 8.2 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ39719.1 - 0.00059 20.1 1.7 1 9.7 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ39719.1 - 0.0048 17.2 0.1 0.11 13.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ39719.1 - 0.027 14.3 0.1 0.5 10.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEZ39719.1 - 0.065 13.6 1.4 0.23 11.8 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 KEZ39719.1 - 0.072 12.1 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 KEZ39719.1 - 0.13 12.3 1.8 16 5.8 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2635 PF10948.8 KEZ39721.1 - 0.02 14.6 0.2 0.035 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Methyltransf_25 PF13649.6 KEZ39722.1 - 2e-15 57.2 0.0 4.4e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39722.1 - 3.3e-15 56.6 0.2 9.9e-15 55.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ39722.1 - 5.5e-14 52.3 0.0 1.2e-13 51.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39722.1 - 2.5e-12 47.3 0.0 5.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39722.1 - 5.6e-09 36.0 0.0 9.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ39722.1 - 4.3e-06 26.2 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ39722.1 - 0.00071 19.2 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 KEZ39722.1 - 0.0032 16.7 0.0 0.16 11.1 0.0 2.4 1 1 2 3 3 3 1 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 KEZ39722.1 - 0.0081 17.2 0.0 0.016 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.8 KEZ39722.1 - 0.011 15.0 0.0 0.031 13.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3419) Methyltransf_16 PF10294.9 KEZ39722.1 - 0.014 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KEZ39722.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KEZ39722.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase3 PF13350.6 KEZ39723.1 - 7.9e-41 140.5 0.0 1.1e-40 140.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KEZ39723.1 - 0.00079 19.0 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEZ39723.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase VEGFR-2_TMD PF17988.1 KEZ39723.1 - 0.34 10.4 3.8 0.67 9.4 3.8 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Eisosome1 PF12757.7 KEZ39724.1 - 1.2e-32 112.8 6.1 1.2e-32 112.8 6.1 3.4 2 2 1 3 3 3 1 Eisosome protein 1 Frag1 PF10277.9 KEZ39725.1 - 5.6e-45 153.6 10.8 6.5e-45 153.4 10.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 KEZ39725.1 - 0.0007 19.2 4.0 0.0007 19.2 4.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF687 PF05095.12 KEZ39725.1 - 0.0058 15.2 1.1 0.0078 14.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF687) Heliorhodopsin PF18761.1 KEZ39725.1 - 0.02 14.2 0.4 0.075 12.3 0.0 2.2 2 1 0 2 2 2 0 Heliorhodopsin 7TM_GPCR_Srh PF10318.9 KEZ39725.1 - 0.026 13.6 3.8 0.043 12.9 3.8 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh EMP70 PF02990.16 KEZ39725.1 - 0.046 12.4 4.2 0.089 11.4 4.2 1.4 1 1 0 1 1 1 0 Endomembrane protein 70 RDD PF06271.12 KEZ39725.1 - 0.18 12.0 10.4 3.1 8.0 0.2 3.5 3 1 0 3 3 3 0 RDD family DUF2955 PF11168.8 KEZ39725.1 - 0.95 9.3 5.9 0.22 11.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) DUF3413 PF11893.8 KEZ39725.1 - 2.7 7.1 11.3 16 4.5 9.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) Mid1 PF12929.7 KEZ39726.1 - 7.5e-137 457.0 1.0 8.9e-137 456.8 1.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KEZ39726.1 - 0.00021 21.9 7.6 0.045 14.4 3.2 2.8 2 1 0 2 2 2 2 Fz domain TB2_DP1_HVA22 PF03134.19 KEZ39727.1 - 1e-27 95.9 9.8 1.6e-27 95.2 9.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.15 KEZ39728.1 - 3.3e-28 98.1 0.0 1.2e-27 96.4 0.1 1.9 2 0 0 2 2 2 1 RFX DNA-binding domain AA_kinase PF00696.28 KEZ39729.1 - 2.5e-38 132.0 0.0 6.7e-38 130.6 0.0 1.7 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 KEZ39729.1 - 7e-13 48.2 4.1 3.1e-10 39.7 0.3 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 KEZ39729.1 - 2.5e-11 43.1 0.7 3.2e-08 33.2 0.1 2.6 2 0 0 2 2 2 2 ACT domain Sec10 PF07393.11 KEZ39730.1 - 1e-166 556.4 0.0 1.2e-166 556.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KEZ39730.1 - 6.7e-09 35.5 0.9 1.9e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEZ39730.1 - 5.3e-06 26.2 0.1 1.3e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain CLPTM1 PF05602.12 KEZ39731.1 - 3.1e-144 481.2 0.0 4.1e-144 480.8 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Sec16_C PF12931.7 KEZ39732.1 - 4.7e-108 361.4 0.0 6.6e-108 360.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KEZ39732.1 - 2.2e-32 112.1 0.0 6e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region TRAP_alpha PF03896.16 KEZ39733.1 - 3.9e-11 42.7 0.0 5.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit IGPD PF00475.18 KEZ39734.1 - 2.1e-60 203.2 0.4 2.8e-60 202.8 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase ArgJ PF01960.18 KEZ39735.1 - 2.1e-148 494.1 0.0 2.3e-148 493.9 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Elong_Iki1 PF10483.9 KEZ39736.1 - 7.8e-98 327.7 0.0 9.1e-98 327.4 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 ASXH PF13919.6 KEZ39737.1 - 4.5e-38 130.4 1.1 6.8e-38 129.8 1.1 1.2 1 0 0 1 1 1 1 Asx homology domain PBP1_TM PF14812.6 KEZ39737.1 - 5.5 7.4 8.5 0.73 10.2 4.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal APH PF01636.23 KEZ39738.1 - 5.9e-17 62.4 0.0 1.2e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KEZ39738.1 - 0.0068 15.8 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KEZ39738.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Longin PF13774.6 KEZ39739.1 - 1e-25 89.6 0.1 1.9e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KEZ39739.1 - 3.3e-15 55.6 0.1 2.4e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 KEZ39739.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5435) SLM4 PF16818.5 KEZ39739.1 - 0.16 11.9 0.1 0.52 10.3 0.0 1.8 1 1 1 2 2 2 0 Protein SLM4 DUF1664 PF07889.12 KEZ39739.1 - 0.87 9.6 6.1 0.61 10.1 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Hus1 PF04005.12 KEZ39741.1 - 6.7e-75 251.9 0.0 7.5e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Med5 PF08689.10 KEZ39742.1 - 3.7e-104 349.6 0.0 4.5e-103 346.0 0.0 2.5 2 1 0 2 2 2 1 Mediator complex subunit Med5 MOR2-PAG1_C PF14225.6 KEZ39742.1 - 0.04 13.8 0.3 0.6 9.9 0.0 2.4 2 0 0 2 2 2 0 Cell morphogenesis C-terminal TetR_C_1 PF02909.17 KEZ39742.1 - 0.12 12.2 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2593 PF10767.9 KEZ39742.1 - 0.17 11.9 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) SNF2_N PF00176.23 KEZ39743.1 - 4.6e-58 196.6 0.0 1e-57 195.5 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KEZ39743.1 - 3.8e-08 33.5 10.2 7.6e-08 32.6 10.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEZ39743.1 - 6.7e-08 32.3 9.0 1.6e-07 31.1 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ39743.1 - 2.1e-07 30.7 10.1 4.5e-07 29.6 10.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ39743.1 - 2.1e-06 27.5 8.8 4.3e-06 26.5 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ39743.1 - 0.00012 21.9 9.7 0.00022 21.1 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KEZ39743.1 - 0.00016 21.9 6.6 0.00042 20.5 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KEZ39743.1 - 0.00032 20.5 9.7 0.00063 19.6 9.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEZ39743.1 - 0.00096 19.1 6.5 0.0015 18.5 3.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger Helicase_C PF00271.31 KEZ39743.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 KEZ39743.1 - 0.32 11.2 5.9 1 9.6 6.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KEZ39743.1 - 1.1 9.1 7.4 1.5 8.7 5.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KEZ39743.1 - 1.4 9.0 8.0 1.2 9.3 5.6 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KEZ39743.1 - 2.9 8.1 5.7 6.5 7.0 5.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KEZ39743.1 - 3.2 7.8 4.8 6.9 6.8 4.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon Baculo_IE-1 PF05290.11 KEZ39743.1 - 3.7 7.5 5.3 5.3 7.0 4.4 1.8 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rad4 PF03835.15 KEZ39744.1 - 0.0041 16.8 6.1 0.0063 16.2 6.1 1.2 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Secretin_N_2 PF07655.13 KEZ39744.1 - 0.34 11.5 7.8 0.95 10.1 7.8 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain SR-25 PF10500.9 KEZ39744.1 - 0.37 10.4 24.6 0.71 9.4 24.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1178 PF06676.11 KEZ39744.1 - 0.65 10.4 5.5 1.1 9.6 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) CDC45 PF02724.14 KEZ39744.1 - 1.8 6.8 14.1 2.3 6.4 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 KEZ39744.1 - 3.9 6.6 5.0 4.6 6.4 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 KEZ39744.1 - 4 6.1 10.1 4.4 6.0 10.1 1.2 1 0 0 1 1 1 0 Presenilin SMAP PF15477.6 KEZ39745.1 - 3.1e-11 44.1 2.8 3.1e-11 44.1 2.8 4.7 2 1 0 2 2 2 1 Small acidic protein family RAMP4 PF06624.12 KEZ39746.1 - 5.9e-21 74.3 0.2 6.4e-21 74.2 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Rox3 PF08633.10 KEZ39747.1 - 2.8e-59 200.9 2.4 4.7e-59 200.1 2.4 1.3 1 0 0 1 1 1 1 Rox3 mediator complex subunit PGAP1 PF07819.13 KEZ39748.1 - 2.7e-06 27.3 0.0 1e-05 25.4 0.0 1.8 1 1 1 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KEZ39748.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ39748.1 - 0.0025 18.4 5.4 0.0025 18.4 5.4 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ39748.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KEZ39748.1 - 0.019 14.8 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KEZ39748.1 - 0.023 14.8 2.0 0.06 13.5 0.1 2.1 2 0 0 2 2 2 0 Thioesterase domain UPF0227 PF05728.12 KEZ39748.1 - 0.097 12.6 0.2 0.097 12.6 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Mito_fiss_reg PF05308.11 KEZ39748.1 - 1.1 9.3 15.6 0.5 10.4 7.0 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Totivirus_coat PF05518.11 KEZ39748.1 - 2.4 6.1 5.6 4.4 5.2 5.6 1.3 1 0 0 1 1 1 0 Totivirus coat protein TIMELESS PF04821.14 KEZ39749.1 - 4.3e-84 282.1 0.0 4.3e-84 282.1 0.0 2.8 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 KEZ39749.1 - 9.2e-19 68.0 37.4 9.2e-19 68.0 37.4 3.8 3 1 0 3 3 3 1 Timeless protein C terminal region Cnd1_N PF12922.7 KEZ39749.1 - 0.04 13.8 0.1 19 5.1 0.0 3.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term 3HCDH_N PF02737.18 KEZ39750.1 - 1.1e-51 175.3 1.5 1.5e-51 174.9 1.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEZ39750.1 - 8.7e-34 116.0 0.0 1.9e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KEZ39750.1 - 0.00042 20.5 0.2 0.001 19.3 0.2 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ39750.1 - 0.094 12.1 0.3 0.32 10.4 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Homeodomain PF00046.29 KEZ39751.1 - 7.8e-18 64.1 3.0 1.5e-17 63.2 3.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KEZ39751.1 - 0.0049 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain GEN1_C PF18380.1 KEZ39751.1 - 0.12 13.3 0.2 0.29 12.0 0.2 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Ribosomal_60s PF00428.19 KEZ39751.1 - 0.57 10.8 3.7 1.3 9.6 3.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein HCO3_cotransp PF00955.21 KEZ39752.1 - 4.5e-83 279.8 10.4 1e-45 156.6 5.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family Peptidase_M41 PF01434.18 KEZ39753.1 - 2.4e-66 223.2 0.1 4.4e-66 222.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEZ39753.1 - 4.5e-42 143.6 0.0 9.2e-42 142.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ39753.1 - 1e-12 47.6 0.0 2.9e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KEZ39753.1 - 1.7e-08 34.8 0.1 5.9e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KEZ39753.1 - 0.0003 20.8 0.0 0.0009 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ39753.1 - 0.0035 17.6 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KEZ39753.1 - 0.0055 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KEZ39753.1 - 0.006 17.0 0.0 0.37 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KEZ39753.1 - 0.0098 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEZ39753.1 - 0.03 14.4 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KEZ39753.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Pap_E4 PF02711.14 KEZ39753.1 - 6.6 7.8 7.2 23 6.0 7.2 1.9 1 0 0 1 1 1 0 E4 protein Fungal_trans PF04082.18 KEZ39754.1 - 9.2e-25 87.2 0.1 2.8e-24 85.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ39754.1 - 2e-10 40.6 11.0 3.6e-10 39.8 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.8 KEZ39754.1 - 0.082 11.6 0.1 0.082 11.6 0.1 1.5 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor DUF2335 PF10097.9 KEZ39754.1 - 0.13 12.2 0.7 0.42 10.6 0.7 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Folliculin PF11704.8 KEZ39754.1 - 0.35 10.7 1.2 1.5 8.7 0.0 2.4 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport ATP11 PF06644.11 KEZ39754.1 - 1.1 9.0 6.3 1.5 8.5 0.7 2.3 2 0 0 2 2 2 0 ATP11 protein Pol_alpha_B_N PF08418.10 KEZ39754.1 - 2.2 8.2 8.1 4.2 7.3 0.6 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Adeno_E3_CR2 PF02439.15 KEZ39755.1 - 0.043 13.6 0.2 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 tRNA-synt_1e PF01406.19 KEZ39756.1 - 2.5e-111 371.9 0.0 3.8e-111 371.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KEZ39756.1 - 0.00018 20.4 0.4 0.51 9.0 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KEZ39756.1 - 0.00024 21.5 0.0 0.00079 19.9 0.0 1.9 1 0 0 1 1 1 1 DALR domain DUF5339 PF17274.2 KEZ39756.1 - 0.1 13.5 4.2 12 6.8 0.2 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5339) LSM PF01423.22 KEZ39758.1 - 6.5e-17 61.0 0.2 9.8e-17 60.4 0.2 1.3 1 0 0 1 1 1 1 LSM domain Ribosomal_S21e PF01249.18 KEZ39758.1 - 0.054 13.6 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S21e UQ_con PF00179.26 KEZ39759.1 - 4.3e-51 172.2 0.0 4.9e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ39759.1 - 0.039 13.7 0.0 0.065 12.9 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B TPR_2 PF07719.17 KEZ39760.1 - 2.9e-05 23.8 0.7 2.6 8.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ39760.1 - 0.0008 19.1 0.9 1.4 8.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ39760.1 - 0.0014 18.9 0.4 0.09 13.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat UBA PF00627.31 KEZ39760.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain TPR_MalT PF17874.1 KEZ39760.1 - 0.11 11.8 0.2 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 MalT-like TPR region DUF1996 PF09362.10 KEZ39761.1 - 1.6e-76 257.4 0.0 2e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Trypan_PARP PF05887.11 KEZ39761.1 - 8.5e-12 45.2 32.1 1.5e-11 44.4 32.1 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) CCDC53 PF10152.9 KEZ39761.1 - 0.19 12.2 1.7 0.27 11.6 1.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Voldacs PF03517.13 KEZ39762.1 - 1.3e-17 64.2 0.2 4.3e-17 62.5 0.2 1.8 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Opi1 PF08618.10 KEZ39764.1 - 4.5e-39 134.9 27.4 1.4e-36 126.7 10.3 4.0 3 1 0 3 3 3 2 Transcription factor Opi1 Het-C PF07217.11 KEZ39764.1 - 0.024 13.2 1.3 0.045 12.3 0.1 1.9 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C FAP206 PF12018.8 KEZ39764.1 - 0.073 12.6 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function ArAE_2_N PF10337.9 KEZ39764.1 - 0.48 9.4 3.6 0.7 8.9 3.6 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal OmpH PF03938.14 KEZ39764.1 - 2 8.7 8.8 1.2 9.5 0.6 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SET PF00856.28 KEZ39765.1 - 7.2e-11 42.8 0.0 1.5e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KEZ39765.1 - 5.1e-08 33.7 0.3 4.5e-07 30.6 0.1 2.4 3 0 0 3 3 3 1 Rubisco LSMT substrate-binding Adap_comp_sub PF00928.21 KEZ39767.1 - 1.2e-91 306.8 0.0 1.9e-91 306.1 0.0 1.3 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEZ39767.1 - 1.7e-08 34.5 0.3 2.8e-08 33.8 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KEZ39767.1 - 0.15 11.5 0.0 0.53 9.7 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain WSC PF01822.19 KEZ39768.1 - 1.4e-14 54.0 6.0 3.2e-14 52.9 6.0 1.6 1 0 0 1 1 1 1 WSC domain PepSY_TM PF03929.16 KEZ39768.1 - 0.12 12.1 0.5 0.22 11.2 0.5 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Mito_carr PF00153.27 KEZ39769.1 - 4.9e-14 52.0 0.3 2.6e-05 24.1 0.0 4.7 3 2 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.13 KEZ39769.1 - 0.0047 17.5 0.4 0.01 16.4 0.4 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) PRIMA1 PF16101.5 KEZ39769.1 - 0.31 11.1 2.9 0.53 10.3 1.9 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Fer2 PF00111.27 KEZ39770.1 - 2e-13 50.1 2.0 2.6e-13 49.7 2.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_45 PF02015.16 KEZ39771.1 - 2.9e-41 141.7 11.7 3.4e-41 141.5 11.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 tRNA-synt_1c PF00749.21 KEZ39772.1 - 2.6e-102 341.9 0.0 3.5e-102 341.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEZ39772.1 - 2.8e-40 138.0 0.1 5.9e-40 137.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KEZ39772.1 - 0.0051 16.2 0.1 0.014 14.8 0.1 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF835 PF05763.12 KEZ39772.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF835) Ribosomal_L1 PF00687.21 KEZ39773.1 - 1.4e-19 70.6 0.0 2.6e-19 69.8 0.0 1.4 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family GRDP-like PF07173.12 KEZ39775.1 - 1.4e-17 64.7 3.5 2e-12 48.0 0.0 3.0 4 0 0 4 4 4 2 Glycine-rich domain-containing protein-like F-box_4 PF15966.5 KEZ39775.1 - 0.0034 17.2 0.1 0.0078 16.1 0.1 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 KEZ39775.1 - 0.09 12.7 0.1 0.29 11.1 0.1 1.9 1 0 0 1 1 1 0 F-box-like 120_Rick_ant PF12574.8 KEZ39775.1 - 0.16 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen NOA36 PF06524.12 KEZ39775.1 - 4.9 6.4 10.5 7.1 5.9 10.5 1.2 1 0 0 1 1 1 0 NOA36 protein GMC_oxred_N PF00732.19 KEZ39776.1 - 1.2e-50 172.6 0.0 1.6e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39776.1 - 4.4e-26 92.1 0.0 7.5e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KEZ39776.1 - 7.3e-05 22.5 0.1 0.00027 20.6 0.0 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ39776.1 - 0.0014 17.8 0.1 0.037 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ39776.1 - 0.0024 18.0 0.1 0.007 16.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ39776.1 - 0.003 16.8 0.0 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEZ39776.1 - 0.014 14.6 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ39776.1 - 0.017 14.4 0.1 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acyltransferase PF01553.21 KEZ39778.1 - 2.9e-17 62.6 0.0 6.8e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DUF2316 PF10078.9 KEZ39778.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) F-box-like PF12937.7 KEZ39779.1 - 2e-07 30.8 0.3 4.9e-07 29.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ39779.1 - 1.9e-05 24.4 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 KEZ39780.1 - 1.4e-20 73.8 0.0 9.2e-20 71.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39780.1 - 1.3e-05 24.6 0.3 0.00015 21.2 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.6 KEZ39781.1 - 2.2e-40 138.7 0.2 4.5e-40 137.7 0.2 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.12 KEZ39781.1 - 3.5e-10 40.0 0.0 1.5e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ39781.1 - 0.0016 18.8 0.2 0.023 15.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ39781.1 - 0.0096 15.8 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KEZ39781.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ39781.1 - 0.062 13.6 0.0 0.33 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain GP52 PF17468.2 KEZ39781.1 - 0.099 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage gene product 52 RNA_helicase PF00910.22 KEZ39781.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KEZ39781.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Alpha_GJ PF03229.13 KEZ39782.1 - 0.0031 18.0 0.1 0.0078 16.8 0.1 1.6 1 0 0 1 1 1 1 Alphavirus glycoprotein J FixQ PF05545.11 KEZ39782.1 - 0.023 14.6 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF4448 PF14610.6 KEZ39782.1 - 0.039 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 KEZ39782.1 - 0.078 11.7 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PTP_tm PF18861.1 KEZ39782.1 - 0.17 11.9 0.5 0.29 11.1 0.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Melittin PF01372.17 KEZ39782.1 - 0.23 11.5 1.2 0.56 10.3 1.2 1.7 1 0 0 1 1 1 0 Melittin F-box PF00646.33 KEZ39784.1 - 0.0091 15.9 0.2 0.022 14.7 0.2 1.6 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.22 KEZ39785.1 - 3e-131 438.1 0.0 3.3e-131 438.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEZ39785.1 - 0.0041 16.2 0.0 0.0093 15.0 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) NMD3 PF04981.13 KEZ39786.1 - 1.7e-76 256.9 0.8 2.6e-76 256.3 0.8 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KEZ39786.1 - 0.36 10.9 5.3 18 5.4 5.3 2.8 1 1 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.8 KEZ39786.1 - 1.2 9.1 7.9 1.9 8.4 0.4 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF3112 PF11309.8 KEZ39788.1 - 7.5e-11 41.9 10.9 2.1e-06 27.4 0.1 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) BatA PF07584.11 KEZ39788.1 - 0.088 13.2 0.3 0.088 13.2 0.3 3.2 3 2 2 5 5 5 0 Aerotolerance regulator N-terminal Aminotran_1_2 PF00155.21 KEZ39789.1 - 1.3e-81 274.6 0.0 1.5e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Adaptin_N PF01602.20 KEZ39790.1 - 6.2e-122 407.8 11.4 7.9e-122 407.5 11.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEZ39790.1 - 5.7e-56 189.0 0.9 5.7e-56 189.0 0.9 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ39790.1 - 1.1e-15 57.8 4.5 8.4e-09 35.7 0.2 4.5 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 KEZ39790.1 - 9.5e-11 41.0 4.5 0.00081 19.4 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KEZ39790.1 - 4.7e-06 27.0 6.8 0.86 10.2 0.0 6.2 5 1 1 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 KEZ39790.1 - 0.003 17.7 1.3 1 9.5 0.0 3.3 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 KEZ39790.1 - 0.004 17.2 0.4 5.5 7.1 0.0 3.9 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KEZ39790.1 - 0.009 16.0 2.3 6.5 7.0 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KEZ39790.1 - 0.024 14.2 2.8 4.3 6.8 0.0 3.2 3 1 0 3 3 3 0 CLASP N terminal DUF1077 PF06417.12 KEZ39791.1 - 1.2e-28 99.5 3.2 2.4e-28 98.5 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Syntaxin-18_N PF10496.9 KEZ39791.1 - 9.8e-11 41.8 0.9 7.7e-10 38.9 0.2 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KEZ39791.1 - 0.0035 17.3 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 SNARE domain NOG1_N PF17835.1 KEZ39791.1 - 0.02 14.8 1.3 0.061 13.3 0.2 2.0 2 0 0 2 2 2 0 NOG1 N-terminal helical domain Pilus_CpaD PF09476.10 KEZ39791.1 - 0.036 13.8 0.4 0.081 12.6 0.4 1.6 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) NBD94 PF16830.5 KEZ39791.1 - 0.058 13.8 0.5 0.16 12.4 0.5 1.7 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Syntaxin PF00804.25 KEZ39791.1 - 0.081 12.6 6.8 0.15 11.7 1.3 2.6 3 0 0 3 3 3 0 Syntaxin TipAS PF07739.13 KEZ39791.1 - 2 9.0 4.9 4.7 7.8 0.3 3.2 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain DUF1640 PF07798.11 KEZ39791.1 - 2.6 8.1 7.8 0.2 11.7 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Rad60-SLD_2 PF13881.6 KEZ39792.1 - 1.9e-11 44.0 0.0 3.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KEZ39792.1 - 0.00063 19.4 0.0 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 KEZ39792.1 - 0.0009 19.8 0.0 0.0018 18.8 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.11 KEZ39793.1 - 2.7e-43 147.0 0.0 3.2e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Mucin PF01456.17 KEZ39793.1 - 1.4 8.9 7.3 2.1 8.3 7.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein BASP1 PF05466.12 KEZ39793.1 - 4.5 7.2 8.1 6.5 6.7 8.1 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) APH PF01636.23 KEZ39794.1 - 8.4e-10 39.0 0.0 1.8e-07 31.3 0.0 2.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ39794.1 - 2.5e-08 33.8 0.0 5.7e-08 32.6 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KEZ39794.1 - 0.0071 15.7 0.2 0.12 11.7 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain DUF1679 PF07914.11 KEZ39794.1 - 0.0076 15.2 0.1 0.03 13.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KEZ39794.1 - 0.24 10.6 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Chitin_synth_1 PF01644.17 KEZ39795.1 - 4.4e-78 260.9 0.2 6.5e-78 260.3 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KEZ39795.1 - 8.6e-28 96.1 0.2 2e-27 95.0 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KEZ39795.1 - 7.8e-24 84.2 1.6 1.8e-20 73.1 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KEZ39795.1 - 1.5e-08 34.8 7.4 9.4e-08 32.2 7.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 NIR_SIR PF01077.22 KEZ39796.1 - 5.4e-55 185.2 0.1 1.3e-48 164.5 0.1 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 KEZ39796.1 - 8.2e-32 110.4 0.0 1.7e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 KEZ39796.1 - 6.2e-31 106.1 0.0 6.3e-15 54.8 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain POR_N PF01855.19 KEZ39796.1 - 2.6e-06 27.4 0.0 5.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KEZ39796.1 - 2e-05 24.8 0.0 6.1e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Kei1 PF08552.11 KEZ39797.1 - 9.5e-52 175.6 7.0 1.4e-51 175.1 7.0 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 KEZ39797.1 - 0.035 14.2 1.3 0.035 14.2 1.3 2.1 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2975 PF11188.8 KEZ39797.1 - 0.07 13.0 2.1 0.11 12.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Rib_5-P_isom_A PF06026.14 KEZ39798.1 - 1.6e-45 154.8 0.0 2.2e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KEZ39798.1 - 0.14 12.1 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Ras PF00071.22 KEZ39799.1 - 3.8e-22 78.6 0.1 5.5e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KEZ39799.1 - 0.00021 20.8 0.1 0.00027 20.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEZ39799.1 - 0.00027 21.1 0.0 0.00056 20.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FlgH PF02107.16 KEZ39799.1 - 0.02 14.5 0.6 0.024 14.3 0.6 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein DNA_pol_E_B PF04042.16 KEZ39799.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Nop53 PF07767.11 KEZ39800.1 - 1.6e-107 360.4 32.0 2e-107 360.1 32.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PRK PF00485.18 KEZ39800.1 - 1.8e-57 194.2 0.0 3.6e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KEZ39800.1 - 9.2e-41 139.6 0.0 1.6e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 KEZ39800.1 - 8.2e-06 25.8 0.0 3.3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KEZ39800.1 - 5.5e-05 23.7 0.0 5.5e-05 23.7 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KEZ39800.1 - 0.00038 20.6 0.0 0.00038 20.6 0.0 3.7 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KEZ39800.1 - 0.013 16.0 2.4 0.02 15.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 KEZ39800.1 - 0.021 15.2 0.1 0.021 15.2 0.1 4.9 4 2 1 5 5 5 0 AAA domain AAA_29 PF13555.6 KEZ39800.1 - 0.027 14.2 0.4 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KEZ39800.1 - 0.08 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 KEZ39800.1 - 0.12 12.5 0.2 1.7 8.8 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 KEZ39800.1 - 0.3 11.2 5.9 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Pyr_redox_2 PF07992.14 KEZ39801.1 - 1.6e-43 149.0 0.0 3e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ39801.1 - 6.6e-14 52.2 0.8 2.3e-10 40.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KEZ39801.1 - 2.5e-07 29.7 0.4 5.9e-07 28.6 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KEZ39801.1 - 5.8e-06 25.8 0.5 1.8e-05 24.3 0.5 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KEZ39801.1 - 8.7e-05 22.9 0.1 0.00019 21.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KEZ39801.1 - 0.00025 20.4 1.6 0.0005 19.5 1.6 1.5 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.6 KEZ39801.1 - 0.0006 19.2 0.0 1 8.6 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase bVLRF1 PF18826.1 KEZ39801.1 - 0.098 12.5 0.3 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 bacteroidetes VLRF1 release factor Tudor-knot PF11717.8 KEZ39802.1 - 1.3e-18 66.6 0.0 3.2e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MOZ_SAS PF01853.18 KEZ39802.1 - 5.6e-08 32.7 0.1 8.4e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family CLTH PF10607.9 KEZ39803.1 - 1.2e-29 103.1 0.0 4.7e-29 101.2 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KEZ39803.1 - 3.8e-06 26.6 0.2 6.8e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 LisH GH131_N PF18271.1 KEZ39803.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain ETC_C1_NDUFA4 PF04800.12 KEZ39804.1 - 1.4e-36 124.6 2.5 2e-36 124.1 2.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 KEZ39805.1 - 3.4e-39 133.2 0.7 3.8e-39 133.1 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KEZ39805.1 - 0.032 14.6 0.1 0.037 14.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f MCM PF00493.23 KEZ39807.1 - 1.3e-103 344.9 0.7 1.3e-103 344.9 0.7 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KEZ39807.1 - 8e-39 132.4 0.4 1.8e-38 131.3 0.4 1.6 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KEZ39807.1 - 1e-32 112.6 0.1 2.4e-32 111.4 0.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KEZ39807.1 - 8.9e-24 83.7 0.6 8.9e-24 83.7 0.6 2.9 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 KEZ39807.1 - 1.4e-23 83.4 0.2 5.5e-23 81.5 0.2 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEZ39807.1 - 2.5e-07 30.3 0.3 9.6e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEZ39807.1 - 0.00092 19.1 0.1 0.0029 17.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEZ39807.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain SUKH_5 PF14567.6 KEZ39807.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 SMI1-KNR4 cell-wall AAA_5 PF07728.14 KEZ39807.1 - 0.044 13.8 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RPAP1_N PF08621.10 KEZ39807.1 - 0.21 11.4 0.7 0.51 10.2 0.7 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal CMAS PF02353.20 KEZ39808.1 - 5.6e-72 242.3 0.0 1.6e-71 240.8 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KEZ39808.1 - 1.9e-11 44.5 0.0 3.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ39808.1 - 3.4e-10 40.0 0.0 6.3e-10 39.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39808.1 - 1.1e-09 38.7 0.0 2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39808.1 - 3.3e-07 30.2 0.0 5.5e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39808.1 - 8.7e-06 26.4 0.0 1.8e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ39808.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 KEZ39808.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.9 KEZ39808.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 KEZ39808.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KEZ39808.1 - 0.18 10.8 0.0 0.36 9.8 0.0 1.4 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Snf7 PF03357.21 KEZ39809.1 - 6.6e-21 74.7 14.4 9.4e-21 74.2 14.4 1.2 1 0 0 1 1 1 1 Snf7 Metalloenzyme PF01676.18 KEZ39809.1 - 0.021 14.2 0.9 0.034 13.5 0.9 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily UTP15_C PF09384.10 KEZ39809.1 - 0.026 14.2 1.4 0.062 13.0 1.4 1.7 1 0 0 1 1 1 0 UTP15 C terminal DUF948 PF06103.11 KEZ39809.1 - 0.036 14.3 9.1 2.2 8.6 0.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Het-C PF07217.11 KEZ39809.1 - 0.04 12.5 2.1 0.07 11.7 2.1 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C SidE PF12252.8 KEZ39809.1 - 0.042 11.4 5.6 0.066 10.7 5.6 1.2 1 0 0 1 1 1 0 Dot/Icm substrate protein Laminin_II PF06009.12 KEZ39809.1 - 0.11 12.5 9.5 2.3 8.2 3.1 2.8 3 0 0 3 3 3 0 Laminin Domain II SOAR PF16533.5 KEZ39809.1 - 0.18 11.8 3.9 6.9 6.7 0.2 3.4 3 1 0 3 3 3 0 STIM1 Orai1-activating region NPV_P10 PF05531.12 KEZ39809.1 - 0.22 12.0 11.6 5.5 7.5 0.3 4.1 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein UPF0184 PF03670.13 KEZ39809.1 - 0.34 11.3 5.1 1.8 9.0 0.6 2.9 2 1 0 3 3 2 0 Uncharacterised protein family (UPF0184) YtxH PF12732.7 KEZ39809.1 - 0.84 10.2 5.2 61 4.2 5.2 2.6 1 1 0 1 1 1 0 YtxH-like protein Baculo_PEP_C PF04513.12 KEZ39809.1 - 1.1 9.3 7.9 15 5.7 5.4 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KEZ39809.1 - 1.7 7.2 9.9 2.5 6.6 9.9 1.1 1 0 0 1 1 1 0 AAA domain Hpt PF01627.23 KEZ39809.1 - 3.2 8.1 9.5 0.39 11.0 4.2 2.4 2 1 0 2 2 2 0 Hpt domain Vps53_N PF04100.12 KEZ39809.1 - 3.4 6.5 8.5 7 5.5 8.2 1.5 1 1 0 1 1 1 0 Vps53-like, N-terminal Not3 PF04065.15 KEZ39809.1 - 3.7 6.9 9.5 8.8 5.7 8.9 1.8 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component BLOC1_2 PF10046.9 KEZ39809.1 - 3.8 7.9 12.4 9.7 6.6 0.4 3.4 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.11 KEZ39809.1 - 5 6.6 6.9 6.7 6.1 5.0 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein PRKG1_interact PF15898.5 KEZ39809.1 - 5.2 8.0 12.2 15 6.5 5.9 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Syntaxin-6_N PF09177.11 KEZ39809.1 - 7 7.3 8.0 40 4.8 3.6 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SAP PF02037.27 KEZ39810.1 - 1.7e-05 24.4 0.1 2.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 SAP domain Sgf11 PF08209.11 KEZ39810.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf_UBZ PF18439.1 KEZ39810.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Kri1 PF05178.12 KEZ39810.1 - 0.75 10.4 3.8 3.4 8.3 3.8 2.0 1 1 0 1 1 1 0 KRI1-like family CDC27 PF09507.10 KEZ39811.1 - 5.7e-58 197.3 18.4 7.8e-58 196.9 18.4 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Aminotran_1_2 PF00155.21 KEZ39811.1 - 1.1e-14 54.5 0.0 1.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Porin_O_P PF07396.11 KEZ39811.1 - 0.00029 20.1 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphate-selective porin O and P NB-ARC PF00931.22 KEZ39811.1 - 0.031 13.5 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Glyco_hydro_125 PF06824.11 KEZ39812.1 - 1.8e-162 541.0 0.0 2.1e-160 534.2 0.0 2.0 1 1 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF5484 PF17583.2 KEZ39813.1 - 0.17 11.5 0.0 0.47 10.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5484) NTP_transf_2 PF01909.23 KEZ39814.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KEZ39814.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF3808 PF10300.9 KEZ39814.1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Pribosyltran_N PF13793.6 KEZ39815.1 - 6.1e-42 142.2 0.0 7e-41 138.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEZ39815.1 - 1.7e-34 119.5 0.0 5.6e-30 104.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEZ39815.1 - 3.2e-07 30.0 0.0 0.00031 20.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Polysacc_deac_1 PF01522.21 KEZ39816.1 - 9.9e-26 90.1 0.0 2.1e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Na_H_Exchanger PF00999.21 KEZ39817.1 - 1.5e-35 122.7 30.7 1.9e-35 122.4 30.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GMC_oxred_N PF00732.19 KEZ39818.1 - 1.4e-56 192.0 0.0 1.8e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39818.1 - 4.9e-22 79.0 0.0 1.1e-21 77.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEZ39818.1 - 2.4e-07 30.2 1.3 2.6e-07 30.1 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KEZ39818.1 - 3.2e-06 27.0 0.2 0.00028 20.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ39818.1 - 4.4e-05 23.6 0.7 0.00011 22.3 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ39818.1 - 7.1e-05 22.2 0.1 0.0031 16.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ39818.1 - 0.00021 20.5 5.0 0.0014 17.8 2.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KEZ39818.1 - 0.00072 18.9 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEZ39818.1 - 0.00098 18.4 1.1 0.0013 18.0 0.2 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KEZ39818.1 - 0.0026 16.5 0.5 0.0065 15.2 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KEZ39818.1 - 0.046 12.6 0.1 0.067 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KEZ39818.1 - 0.048 14.2 0.4 0.33 11.5 0.1 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEZ39818.1 - 0.069 13.4 0.2 0.7 10.2 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KEZ39818.1 - 0.26 10.5 2.3 3.6 6.8 1.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KEZ39818.1 - 0.28 9.6 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor GIDA PF01134.22 KEZ39818.1 - 0.37 9.8 1.6 0.31 10.1 0.2 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ39818.1 - 2.7 7.2 4.2 1.2 8.4 1.9 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase PGG PF13962.6 KEZ39819.1 - 0.024 14.4 0.0 0.24 11.2 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF1467 PF07330.12 KEZ39819.1 - 0.19 11.7 2.4 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) DUF4199 PF13858.6 KEZ39819.1 - 0.5 10.8 0.0 0.5 10.8 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) DUF1419 PF07215.11 KEZ39820.1 - 0.083 13.0 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) Sugar_tr PF00083.24 KEZ39821.1 - 1.9e-21 76.5 22.7 5.3e-11 42.1 9.6 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39821.1 - 8.9e-13 47.9 12.4 1.1e-05 24.5 2.8 3.2 2 1 2 4 4 3 3 Major Facilitator Superfamily MscS_TM PF12794.7 KEZ39821.1 - 0.022 13.6 0.9 0.098 11.5 0.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Pkinase PF00069.25 KEZ39823.1 - 1.1e-23 83.9 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.11 KEZ39823.1 - 3.3e-23 82.7 0.0 6.7e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KEZ39824.1 - 2.3e-15 56.7 0.0 3.3e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39824.1 - 8.4e-07 28.5 0.0 0.0031 16.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase p450 PF00067.22 KEZ39825.1 - 1.6e-17 63.4 0.0 5.4e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 KEZ39827.1 - 7.8e-85 284.8 33.3 2.3e-43 148.8 9.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ39827.1 - 1.4e-70 236.2 0.0 4.3e-34 118.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ39827.1 - 1.1e-13 51.1 3.7 4.2e-05 23.1 0.0 4.0 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 KEZ39827.1 - 6.7e-09 35.1 0.4 0.0033 16.3 0.1 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 KEZ39827.1 - 9.3e-09 34.9 0.4 0.00092 18.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ39827.1 - 2.1e-08 34.7 0.2 0.0013 19.2 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEZ39827.1 - 2.6e-08 34.2 0.0 0.0084 16.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEZ39827.1 - 1.3e-07 31.7 0.0 0.01 15.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KEZ39827.1 - 5.8e-06 26.0 0.1 0.11 12.0 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KEZ39827.1 - 1.1e-05 25.4 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KEZ39827.1 - 2.2e-05 24.4 1.1 0.12 12.1 0.2 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ39827.1 - 2.2e-05 25.1 0.0 0.025 15.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEZ39827.1 - 2.7e-05 24.0 0.1 0.23 11.2 0.0 3.3 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 KEZ39827.1 - 0.00016 21.0 0.1 1 8.6 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA PF00004.29 KEZ39827.1 - 0.00018 22.0 0.1 5.7 7.4 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ39827.1 - 0.00057 20.1 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KEZ39827.1 - 0.00099 19.3 0.0 0.88 9.6 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_28 PF13521.6 KEZ39827.1 - 0.0015 18.8 0.2 0.77 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEZ39827.1 - 0.0021 18.1 0.1 3.7 7.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ39827.1 - 0.0023 17.5 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 KEZ39827.1 - 0.0026 17.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 KEZ39827.1 - 0.0034 17.9 0.2 3.5 8.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 KEZ39827.1 - 0.0088 15.7 0.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 KEZ39827.1 - 0.0098 16.0 0.1 3.3 7.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 KEZ39827.1 - 0.023 13.9 0.0 5.2 6.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 KEZ39827.1 - 0.024 15.0 0.1 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.20 KEZ39827.1 - 0.044 13.7 0.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 KEZ39827.1 - 0.051 12.8 0.1 5.5 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KEZ39827.1 - 0.052 13.3 0.0 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KEZ39827.1 - 0.058 13.6 5.4 6.2 7.1 0.2 4.2 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Ploopntkinase3 PF18751.1 KEZ39827.1 - 0.11 12.4 0.1 25 4.7 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 PRK PF00485.18 KEZ39827.1 - 0.17 11.6 0.1 20 4.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Fungal_trans PF04082.18 KEZ39828.1 - 1.6e-12 47.0 0.0 4.8e-12 45.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 KEZ39829.1 - 1.2e-33 116.2 0.1 1.4e-33 116.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ39829.1 - 9.2e-23 81.0 0.0 1.1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ39829.1 - 1.3e-09 38.3 0.0 1.5e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ39829.1 - 0.03 13.5 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 KEZ39830.1 - 3.4e-11 43.0 0.0 3.5e-10 39.7 0.0 2.4 1 1 0 1 1 1 1 ThiF family Fungal_trans PF04082.18 KEZ39831.1 - 3.7e-23 81.9 0.0 6.8e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KEZ39832.1 - 1.8e-110 369.9 17.7 2.3e-110 369.6 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39832.1 - 7.3e-22 77.8 39.1 2.8e-21 75.9 20.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39833.1 - 9.1e-86 288.5 14.1 1.1e-85 288.2 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39833.1 - 4e-28 98.4 12.3 6.2e-28 97.7 12.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ39833.1 - 2e-05 23.2 0.7 2e-05 23.2 0.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KEZ39833.1 - 2.2e-05 23.2 8.8 0.0042 15.7 1.9 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Bcl-2_3 PF15286.6 KEZ39833.1 - 0.085 13.5 0.1 0.19 12.4 0.1 1.5 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like C2 PF00168.30 KEZ39834.1 - 1.4e-20 73.5 0.1 1.5e-12 47.7 0.3 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 KEZ39834.1 - 7.1e-15 54.9 0.2 1.2e-14 54.1 0.2 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain F-box-like PF12937.7 KEZ39835.1 - 0.00044 20.1 2.4 0.00055 19.8 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KEZ39835.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box FAD_binding_4 PF01565.23 KEZ39836.1 - 2.3e-25 88.9 1.0 4e-25 88.2 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.13 KEZ39837.1 - 1.1e-09 38.2 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family FAD_binding_4 PF01565.23 KEZ39838.1 - 4.6e-21 75.0 1.3 8.9e-21 74.1 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ39838.1 - 2.7e-11 43.4 0.2 9.2e-10 38.5 0.0 2.5 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.16 KEZ39839.1 - 7.2e-44 150.1 27.5 4.6e-40 137.6 18.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39839.1 - 4.7e-11 42.2 8.3 4.7e-11 42.2 8.3 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ39839.1 - 0.00029 19.4 4.7 0.0006 18.4 4.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KEZ39839.1 - 0.17 10.3 9.8 0.055 11.9 2.6 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 KEZ39839.1 - 2.7 6.2 4.9 1.2 7.3 0.1 2.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Meth_synt_2 PF01717.18 KEZ39840.1 - 9.6e-17 61.2 0.0 4.2e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KEZ39840.1 - 2.3e-07 30.6 0.1 0.00056 19.5 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain ACD PF16671.5 KEZ39840.1 - 0.085 11.2 0.2 0.15 10.3 0.1 1.4 2 0 0 2 2 2 0 Actin cross-linking domain adh_short PF00106.25 KEZ39841.1 - 4.1e-12 46.0 0.0 4.2e-05 23.1 0.0 3.3 3 0 0 3 3 3 3 short chain dehydrogenase KR PF08659.10 KEZ39841.1 - 0.012 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 KR domain GMC_oxred_N PF00732.19 KEZ39842.1 - 1.1e-37 130.1 0.0 3.6e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ39842.1 - 3.1e-24 86.1 0.0 5e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEZ39842.1 - 1.4e-05 24.5 0.3 7.1e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ39842.1 - 0.0035 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ39842.1 - 0.0059 16.8 0.1 0.0059 16.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ39842.1 - 0.024 13.9 0.2 6.9 5.8 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ39842.1 - 0.025 13.7 0.4 0.048 12.7 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KEZ39842.1 - 0.059 12.6 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KEZ39842.1 - 0.13 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein zf-TRM13_CCCH PF11722.8 KEZ39843.1 - 0.055 13.2 0.1 0.055 13.2 0.1 4.1 5 0 0 5 5 5 0 CCCH zinc finger in TRM13 protein Sugar_tr PF00083.24 KEZ39844.1 - 1.8e-60 205.1 14.3 6.1e-60 203.4 10.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter DUF1129 PF06570.11 KEZ39844.1 - 3.6 7.0 11.0 2 7.8 3.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) Glyco_hydro_61 PF03443.14 KEZ39845.1 - 2.6e-37 128.8 0.0 3.6e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_S15 PF02129.18 KEZ39846.1 - 1e-38 133.5 0.1 1.4e-38 133.0 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KEZ39846.1 - 1.1e-20 74.5 0.0 1.9e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 KEZ39846.1 - 0.022 14.2 1.2 0.038 13.5 1.2 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ39846.1 - 0.031 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 KEZ39847.1 - 1.6e-23 83.2 0.0 2e-11 43.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.23 KEZ39848.1 - 1e-22 80.4 0.0 1.5e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ39848.1 - 1e-06 28.6 0.0 2e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.24 KEZ39850.1 - 1.6e-72 244.8 21.9 1.8e-72 244.6 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39850.1 - 6.7e-19 68.0 38.1 6.7e-19 68.0 38.1 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ39850.1 - 3.1e-06 25.9 1.3 6.1e-06 24.9 1.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YchF-GTPase_C PF06071.13 KEZ39850.1 - 0.029 14.6 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Zn_clus PF00172.18 KEZ39851.1 - 1.5e-10 41.0 7.7 3.3e-10 39.9 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 KEZ39852.1 - 7e-13 49.3 0.1 3.4e-12 47.1 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KEZ39852.1 - 0.025 15.0 0.0 0.075 13.4 0.0 1.9 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase GFO_IDH_MocA PF01408.22 KEZ39853.1 - 5.6e-20 72.4 0.1 3.8e-19 69.7 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_2 PF00703.21 KEZ39854.1 - 6.3e-15 55.8 0.5 6.3e-15 55.8 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KEZ39854.1 - 7.2e-08 32.9 0.1 7.2e-08 32.9 0.1 2.1 2 1 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KEZ39854.1 - 0.00057 19.6 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Ig_GlcNase PF18368.1 KEZ39854.1 - 0.04 14.1 0.0 0.18 11.9 0.0 2.1 1 1 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain NMT1 PF09084.11 KEZ39855.1 - 6e-06 26.3 0.0 1.2e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 KEZ39855.1 - 8.2e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 KEZ39855.1 - 3.2e-05 23.5 0.0 0.00023 20.7 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF3834 PF12916.7 KEZ39855.1 - 0.17 11.1 0.0 0.5 9.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) NACHT PF05729.12 KEZ39856.1 - 7.9e-11 42.1 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ39856.1 - 2.5e-06 28.0 0.0 4.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 KEZ39856.1 - 0.01 15.1 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KEZ39856.1 - 0.01 16.2 0.0 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KEZ39856.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 KEZ39856.1 - 0.035 13.0 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KAP_NTPase PF07693.14 KEZ39856.1 - 0.061 12.5 0.1 0.17 11.1 0.1 1.8 1 1 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 KEZ39856.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein COesterase PF00135.28 KEZ39857.1 - 2.2e-51 175.3 0.0 2.8e-40 138.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ39857.1 - 0.00038 20.4 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KEZ39858.1 - 1.1e-28 100.2 32.9 1.5e-28 99.8 32.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2371 PF10177.9 KEZ39858.1 - 0.018 15.2 0.3 0.62 10.2 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) AAA_12 PF13087.6 KEZ39859.1 - 8e-37 126.8 0.0 1.4e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ39859.1 - 3.7e-19 69.6 0.1 2.9e-18 66.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 KEZ39859.1 - 2.8e-07 30.3 4.6 7.1e-07 29.0 4.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2075 PF09848.9 KEZ39859.1 - 6.1e-06 25.7 0.1 0.073 12.3 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KEZ39859.1 - 6.9e-06 26.5 0.0 0.00016 22.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain zf_CCCH_4 PF18345.1 KEZ39859.1 - 8.6e-06 25.6 6.3 1.7e-05 24.7 6.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEZ39859.1 - 0.00019 21.1 5.3 0.00035 20.3 4.5 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger AAA_30 PF13604.6 KEZ39859.1 - 0.0075 16.0 0.1 0.25 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ39859.1 - 0.11 12.8 0.1 1.9 8.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain zf-CCCH_2 PF14608.6 KEZ39859.1 - 0.2 12.2 2.9 0.54 10.8 2.9 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Methyltransf_23 PF13489.6 KEZ39862.1 - 3.4e-19 69.3 0.0 6.6e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39862.1 - 1.5e-11 44.9 0.0 5.1e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39862.1 - 4.3e-08 33.1 0.0 4e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39862.1 - 2.7e-07 31.2 0.0 5.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39862.1 - 1.8e-06 28.6 0.0 1e-05 26.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ39862.1 - 0.00015 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEZ39862.1 - 0.00035 20.7 0.0 0.00059 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KEZ39862.1 - 0.0058 16.0 0.0 0.029 13.6 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KEZ39862.1 - 0.0079 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KEZ39862.1 - 0.0083 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KEZ39862.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KEZ39862.1 - 0.087 12.6 0.0 1.8 8.2 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 KEZ39862.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 KEZ39863.1 - 4.7e-19 68.8 0.0 7.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ39863.1 - 1.4e-11 45.0 0.0 5.2e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ39863.1 - 3.4e-10 40.4 0.0 7.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ39863.1 - 1.8e-07 31.1 0.0 0.0039 17.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ39863.1 - 8.8e-07 29.6 0.0 3.6e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ39863.1 - 0.00018 20.9 0.0 0.0031 16.9 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ39863.1 - 0.003 17.1 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ39863.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KEZ39863.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEZ39863.1 - 0.038 13.7 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Thioredoxin_4 PF13462.6 KEZ39863.1 - 0.37 10.9 1.4 0.63 10.2 0.0 2.1 3 0 0 3 3 3 0 Thioredoxin Pkinase PF00069.25 KEZ39864.1 - 3.8e-22 78.9 0.0 6.2e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39864.1 - 1.3e-09 37.7 0.0 8.5e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KEZ39864.1 - 0.026 14.4 0.0 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ39864.1 - 0.12 11.1 0.0 0.26 10.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF346 PF03984.13 KEZ39865.1 - 0.0063 16.2 1.8 0.0063 16.2 1.8 5.1 5 0 0 5 5 5 2 Repeat of unknown function (DUF346) F-box PF00646.33 KEZ39866.1 - 0.00017 21.4 0.1 0.0027 17.6 0.0 2.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KEZ39866.1 - 0.15 12.0 0.7 0.44 10.4 0.3 2.1 2 0 0 2 2 2 0 F-box CorA PF01544.18 KEZ39867.1 - 9.8e-11 41.5 6.4 4.9e-10 39.2 0.1 3.3 3 1 0 3 3 3 1 CorA-like Mg2+ transporter protein GP41 PF00517.17 KEZ39867.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Retroviral envelope protein DUF501 PF04417.12 KEZ39867.1 - 0.69 9.7 4.3 1.8 8.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Exonuc_VII_L PF02601.15 KEZ39867.1 - 1.2 8.6 8.9 9.7 5.7 0.2 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit zf-CCCH PF00642.24 KEZ39868.1 - 4.4e-09 36.0 2.7 9.1e-09 35.0 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KEZ39868.1 - 5.7e-08 32.5 5.2 1e-07 31.7 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ39868.1 - 1.1e-07 31.5 7.5 2.2e-07 30.6 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ39868.1 - 1.2e-06 28.5 5.6 2.5e-06 27.4 5.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEZ39868.1 - 2.2e-06 27.4 9.1 4e-06 26.6 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ39868.1 - 9.8e-06 25.4 8.0 1.9e-05 24.5 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 KEZ39868.1 - 1.7e-05 24.7 6.2 3.2e-05 23.8 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 KEZ39868.1 - 2.1e-05 24.6 3.1 2.1e-05 24.6 3.1 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KEZ39868.1 - 6.2e-05 23.2 6.6 0.00012 22.3 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KEZ39868.1 - 0.00022 20.9 2.4 0.00022 20.9 2.4 2.0 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KEZ39868.1 - 0.00048 19.9 5.1 0.00092 19.0 5.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEZ39868.1 - 0.0011 19.1 7.1 0.0027 17.8 7.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Siva PF05458.12 KEZ39868.1 - 0.0065 16.2 0.6 0.01 15.5 0.6 1.3 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Cript PF10235.9 KEZ39868.1 - 0.03 14.9 2.2 0.03 14.9 2.2 1.9 2 0 0 2 2 1 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.7 KEZ39868.1 - 0.068 13.5 3.1 0.14 12.4 3.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KEZ39868.1 - 0.11 12.1 3.1 0.23 11.1 3.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ribosomal_L34e PF01199.18 KEZ39868.1 - 0.3 11.4 2.4 1.9 8.9 1.1 2.6 1 1 1 2 2 2 0 Ribosomal protein L34e zf-CCCH_2 PF14608.6 KEZ39868.1 - 0.38 11.3 4.8 0.77 10.3 4.8 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Beta-lactamase PF00144.24 KEZ39871.1 - 5.5e-32 111.3 0.0 5e-31 108.2 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase Zn_clus PF00172.18 KEZ39871.1 - 3.1e-06 27.2 6.2 5.8e-06 26.3 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2985 PF11204.8 KEZ39872.1 - 2.6e-20 72.4 4.1 2.6e-20 72.4 4.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) ABC_tran PF00005.27 KEZ39873.1 - 3.7e-69 231.5 0.0 1.2e-33 116.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEZ39873.1 - 5.6e-44 150.8 10.7 8e-44 150.3 10.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KEZ39873.1 - 9.4e-14 51.4 2.3 0.00011 21.7 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ39873.1 - 6.9e-08 32.1 1.1 0.0014 18.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KEZ39873.1 - 7.4e-08 31.6 2.1 0.0014 17.5 0.1 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KEZ39873.1 - 1.1e-07 32.3 0.1 0.08 13.2 0.1 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KEZ39873.1 - 1.7e-07 31.3 0.0 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KEZ39873.1 - 7.3e-07 29.3 0.4 0.16 11.8 0.1 4.3 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ39873.1 - 1.9e-06 28.3 0.4 0.039 14.3 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 KEZ39873.1 - 2.2e-05 24.1 0.0 0.049 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KEZ39873.1 - 2.5e-05 24.2 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KEZ39873.1 - 2.8e-05 23.9 0.6 0.66 9.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 KEZ39873.1 - 0.00026 21.6 0.1 0.097 13.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEZ39873.1 - 0.0007 19.2 0.0 0.86 9.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 KEZ39873.1 - 0.00079 19.9 0.3 7 7.1 0.0 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KEZ39873.1 - 0.00089 18.6 1.1 0.46 9.7 0.0 3.0 4 0 0 4 4 3 1 Zeta toxin AAA_33 PF13671.6 KEZ39873.1 - 0.0036 17.5 0.2 3.6 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEZ39873.1 - 0.0036 17.6 0.2 1 9.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ39873.1 - 0.0039 17.7 0.0 3.4 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain F-box-like PF12937.7 KEZ39873.1 - 0.0046 16.8 0.1 0.0097 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like AAA_5 PF07728.14 KEZ39873.1 - 0.0052 16.8 0.1 5.5 7.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KEZ39873.1 - 0.0063 16.5 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 KEZ39873.1 - 0.011 15.0 0.1 0.95 8.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 KEZ39873.1 - 0.015 15.4 0.2 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KEZ39873.1 - 0.016 15.3 0.1 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KEZ39873.1 - 0.025 14.8 3.2 10 6.5 0.4 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 KEZ39873.1 - 0.032 14.6 0.1 4.2 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 KEZ39873.1 - 0.098 12.3 0.1 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KEZ39873.1 - 0.12 11.6 0.4 4.8 6.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KEZ39873.1 - 0.16 11.7 0.2 13 5.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KEZ39873.1 - 0.16 11.7 0.1 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein p450 PF00067.22 KEZ39874.1 - 3.1e-55 187.8 0.0 4e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KEZ39875.1 - 4.3e-06 25.9 0.1 6.6e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phosphoesterase PF04185.14 KEZ39876.1 - 2.2e-31 109.3 0.3 2.4e-27 96.1 0.1 2.0 1 1 1 2 2 2 2 Phosphoesterase family Fungal_trans PF04082.18 KEZ39878.1 - 7.7e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BT1 PF03092.16 KEZ39878.1 - 0.069 11.4 0.0 0.095 10.9 0.0 1.2 1 0 0 1 1 1 0 BT1 family DUF1404 PF07185.11 KEZ39878.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) FAD_binding_3 PF01494.19 KEZ39879.1 - 1e-18 67.7 0.1 3.8e-18 65.8 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ39879.1 - 1.3e-06 27.9 0.1 2.8e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ39879.1 - 0.00014 22.0 0.8 0.00034 20.8 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ39879.1 - 0.00064 18.9 1.0 0.0012 18.0 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 KEZ39879.1 - 0.0016 17.4 0.1 0.0091 14.9 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 KEZ39879.1 - 0.0018 18.0 2.7 0.014 15.0 1.4 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEZ39879.1 - 0.0039 16.6 0.5 0.0073 15.7 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ39879.1 - 0.0074 15.4 0.7 0.015 14.4 0.7 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEZ39879.1 - 0.03 13.6 0.5 1.1 8.5 0.2 2.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KEZ39879.1 - 0.044 14.3 0.4 0.12 13.0 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ39879.1 - 0.048 13.0 0.2 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEZ39879.1 - 0.048 12.4 0.6 0.095 11.4 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein SE PF08491.10 KEZ39879.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase MFS_1 PF07690.16 KEZ39880.1 - 1.5e-24 86.6 48.2 3.2e-21 75.6 40.9 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ39880.1 - 5e-21 74.8 23.1 7.7e-21 74.1 23.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PIRT PF15099.6 KEZ39880.1 - 0.48 10.0 8.2 9.3 5.8 0.1 3.9 4 0 0 4 4 4 0 Phosphoinositide-interacting protein family Sugar_tr PF00083.24 KEZ39882.1 - 1.8e-89 300.7 17.1 2.1e-89 300.4 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ39882.1 - 1.2e-34 119.9 40.0 3.7e-28 98.5 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Claudin_2 PF13903.6 KEZ39882.1 - 0.065 13.0 0.4 0.065 13.0 0.4 2.9 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction OATP PF03137.20 KEZ39882.1 - 0.076 11.3 3.5 0.16 10.2 3.4 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AnmK PF03702.14 KEZ39883.1 - 6.9e-89 298.5 0.0 8.2e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase DUF768 PF05589.11 KEZ39883.1 - 0.028 14.4 0.2 0.073 13.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF768) BcrAD_BadFG PF01869.20 KEZ39883.1 - 0.058 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MFS_1 PF07690.16 KEZ39884.1 - 3.8e-36 124.7 22.2 3.8e-36 124.7 22.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugarporin_N PF11471.8 KEZ39884.1 - 0.88 9.6 3.4 7.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Patatin PF01734.22 KEZ39886.1 - 7.5e-26 91.6 0.1 1.9e-25 90.3 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 KEZ39886.1 - 0.0022 18.5 0.0 0.006 17.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KEZ39886.1 - 0.0036 17.0 0.1 0.022 14.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEZ39886.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-C3HC4_4 PF15227.6 KEZ39886.1 - 0.021 15.0 14.0 0.55 10.4 0.8 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING NACHT PF05729.12 KEZ39886.1 - 0.028 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KEZ39886.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEZ39886.1 - 0.049 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ39886.1 - 0.077 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KEZ39886.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin zf-RING_5 PF14634.6 KEZ39886.1 - 0.22 11.5 17.0 0.013 15.5 6.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain FtsK_SpoIIIE PF01580.18 KEZ39886.1 - 0.24 10.7 0.0 0.42 9.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family zf-RING_2 PF13639.6 KEZ39886.1 - 0.52 10.7 22.6 1.7 9.0 8.6 2.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 KEZ39886.1 - 0.96 9.5 19.1 0.11 12.5 4.0 3.1 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_13 PF17977.1 KEZ39886.1 - 3.7 7.8 7.5 2.1 8.5 4.9 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 KEZ39886.1 - 3.7 7.8 8.3 5.9 7.1 0.9 2.8 2 0 0 2 2 2 0 FYVE zinc finger Vps36-NZF-N PF16988.5 KEZ39886.1 - 4.5 6.7 5.7 0.27 10.7 0.1 1.9 2 0 0 2 2 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Stig1 PF04885.13 KEZ39887.1 - 0.16 12.5 11.0 0.52 10.8 11.0 1.9 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 p450 PF00067.22 KEZ39888.1 - 5.7e-60 203.4 0.0 7.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NDK PF00334.19 KEZ39889.1 - 3e-54 182.7 0.0 3.8e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 KEZ39890.1 - 3.4e-25 88.2 0.1 4.9e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA E1-E2_ATPase PF00122.20 KEZ39891.1 - 0.0031 17.1 1.7 0.0031 17.1 1.7 1.5 2 0 0 2 2 2 1 E1-E2 ATPase MARVEL PF01284.23 KEZ39891.1 - 0.0042 17.1 12.2 0.0042 17.1 12.2 1.5 2 0 0 2 2 2 1 Membrane-associating domain DUF1189 PF06691.11 KEZ39891.1 - 0.11 12.0 7.7 0.19 11.3 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Herpes_LMP1 PF05297.11 KEZ39891.1 - 1.5 7.9 8.2 1.7 7.7 8.2 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4133 PF13571.6 KEZ39891.1 - 1.8 8.9 5.4 2.2 8.7 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4133) Glyco_hydro_31 PF01055.26 KEZ39892.1 - 9.9e-144 479.8 4.4 1.5e-143 479.2 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 RmlD_sub_bind PF04321.17 KEZ39892.1 - 9e-51 172.7 0.0 1.7e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Gal_mutarotas_2 PF13802.6 KEZ39892.1 - 9e-22 77.2 0.8 6e-21 74.5 0.2 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Epimerase PF01370.21 KEZ39892.1 - 6.1e-18 65.2 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEZ39892.1 - 3.9e-08 32.8 0.1 8.5e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KEZ39892.1 - 8.2e-08 32.0 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ39892.1 - 1.8e-07 30.4 0.0 3.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF5110 PF17137.4 KEZ39892.1 - 3.3e-07 30.5 0.4 1.2e-06 28.7 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Polysacc_synt_2 PF02719.15 KEZ39892.1 - 4.8e-05 22.6 0.1 0.00079 18.6 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein polyprenyl_synt PF00348.17 KEZ39894.1 - 6.4e-90 300.7 0.0 8.6e-90 300.2 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase NACHT_N PF17100.5 KEZ39895.1 - 3.8e-20 72.7 0.1 3.2e-19 69.7 0.1 2.3 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Syntaxin-18_N PF10496.9 KEZ39895.1 - 0.028 14.7 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus KaiA PF07688.12 KEZ39895.1 - 0.11 12.7 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 KaiA C-terminal domain Dak2 PF02734.17 KEZ39895.1 - 0.14 12.0 0.0 8.3 6.3 0.0 2.7 3 0 0 3 3 3 0 DAK2 domain BTB PF00651.31 KEZ39896.1 - 0.00024 21.3 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain ANAPC8 PF04049.13 KEZ39897.1 - 3.8e-55 185.8 1.1 1.5e-54 183.8 0.1 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KEZ39897.1 - 1.9e-23 81.3 8.2 8.7e-05 22.2 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ39897.1 - 1.1e-22 78.2 11.7 6.9e-05 22.8 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ39897.1 - 8.3e-15 53.6 19.0 0.03 14.4 0.0 8.7 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ39897.1 - 6.1e-13 48.4 12.4 0.0057 17.4 0.1 8.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ39897.1 - 7.2e-09 35.1 6.9 0.045 13.8 0.0 5.8 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ39897.1 - 1.3e-08 34.4 1.1 1.1e-06 28.2 0.1 3.7 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KEZ39897.1 - 8.2e-08 32.4 16.4 0.26 11.6 0.1 7.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ39897.1 - 9.6e-08 32.6 6.0 1.3e-05 25.8 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ39897.1 - 4.1e-06 26.9 12.0 0.05 13.8 0.3 6.6 5 1 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KEZ39897.1 - 1.7e-05 25.2 6.9 4.6 7.8 0.0 7.2 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ39897.1 - 6.5e-05 23.0 13.1 2.1 8.5 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF3856 PF12968.7 KEZ39897.1 - 0.0035 17.4 1.4 0.34 11.0 0.2 3.3 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 KEZ39897.1 - 0.0067 16.7 1.1 6 7.5 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat Say1_Mug180 PF10340.9 KEZ39897.1 - 0.056 12.3 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_6 PF13174.6 KEZ39897.1 - 0.057 14.1 17.6 7.1 7.5 0.1 8.0 9 1 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEZ39897.1 - 0.068 13.3 1.2 16 5.6 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KEZ39897.1 - 0.073 12.1 0.0 0.73 8.8 0.0 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KEZ39897.1 - 0.12 12.3 10.2 0.26 11.2 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ39897.1 - 0.18 10.9 4.4 0.32 10.2 1.7 2.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 KEZ39897.1 - 4.4 8.1 11.4 48 4.8 0.1 5.3 5 0 0 5 5 5 0 Sel1 repeat Pkinase PF00069.25 KEZ39898.1 - 2.2e-15 56.7 0.0 4.6e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39898.1 - 5.5e-09 35.7 0.0 6e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KEZ39898.1 - 0.0025 17.8 0.1 0.16 11.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEZ39898.1 - 0.0038 16.3 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Pro-NT_NN PF07421.11 KEZ39898.1 - 0.2 11.9 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Vps54 PF07928.12 KEZ39899.1 - 3.8e-52 176.3 0.2 1.2e-51 174.7 0.1 1.9 2 0 0 2 2 2 1 Vps54-like protein DUF2451 PF10474.9 KEZ39899.1 - 2.8e-07 30.6 0.0 5.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KEZ39899.1 - 1.1e-06 28.2 0.7 2.6e-06 26.9 0.7 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 KEZ39899.1 - 0.43 10.7 2.3 1.2 9.2 0.5 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.23 KEZ39900.1 - 1.6e-105 351.2 0.5 5.5e-105 349.4 0.1 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KEZ39900.1 - 5.4e-36 123.2 0.5 1e-35 122.3 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEZ39900.1 - 4.9e-28 97.4 2.0 1.1e-27 96.2 2.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEZ39900.1 - 3.1e-16 59.9 0.5 6.6e-16 58.8 0.5 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEZ39900.1 - 7.6e-07 28.7 0.0 0.00022 20.7 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEZ39900.1 - 2.1e-05 24.6 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEZ39900.1 - 0.00021 21.1 0.1 0.0008 19.3 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEZ39900.1 - 0.056 13.1 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Nop16 PF09420.10 KEZ39901.1 - 9.5e-69 231.6 10.1 1.1e-68 231.4 10.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 eIF3_subunit PF08597.10 KEZ39901.1 - 0.017 15.0 9.7 0.035 14.0 9.7 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spt5_N PF11942.8 KEZ39901.1 - 0.066 14.2 14.0 0.15 13.1 14.0 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal MARVEL PF01284.23 KEZ39902.1 - 5.2e-06 26.6 7.3 8.9e-06 25.8 7.3 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 KEZ39902.1 - 0.0023 18.3 1.1 0.0045 17.4 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) MFS_1 PF07690.16 KEZ39903.1 - 1.2e-40 139.5 44.6 1.2e-40 139.5 44.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ39903.1 - 4.4e-15 55.5 13.0 4.4e-15 55.5 13.0 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter SLC3A2_N PF16028.5 KEZ39903.1 - 0.34 10.5 2.1 6.5 6.4 0.1 2.6 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus GATase_6 PF13522.6 KEZ39904.1 - 6.7e-14 52.2 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEZ39904.1 - 1.2e-11 44.6 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KEZ39904.1 - 3.2e-08 33.2 0.1 7.4e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DAO PF01266.24 KEZ39905.1 - 5.5e-69 233.4 0.9 6.5e-69 233.2 0.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ39905.1 - 3.3e-06 26.6 0.3 0.062 12.5 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ39905.1 - 2.7e-05 24.6 0.1 0.086 13.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ39905.1 - 0.00013 22.1 0.1 0.00033 20.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEZ39905.1 - 0.00072 18.5 0.3 0.011 14.6 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Mqo PF06039.15 KEZ39905.1 - 0.01 14.5 0.0 1.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 KEZ39905.1 - 0.046 13.0 0.3 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KEZ39905.1 - 0.065 12.3 0.8 0.28 10.2 0.8 1.9 1 1 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.19 KEZ39905.1 - 0.21 11.0 0.1 14 5.0 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase MCRA PF06100.11 KEZ39905.1 - 0.34 9.7 0.8 5.8 5.6 0.1 2.1 2 0 0 2 2 2 0 MCRA family GSHPx PF00255.19 KEZ39906.1 - 2.1e-41 139.9 0.0 2.6e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KEZ39906.1 - 0.00034 20.5 0.1 0.00065 19.6 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ39906.1 - 0.0048 16.6 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Fungal_trans_2 PF11951.8 KEZ39907.1 - 9.9e-54 182.6 3.8 5.7e-31 107.7 1.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ39907.1 - 3.2e-06 27.1 6.6 8.2e-06 25.9 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 KEZ39908.1 - 4.5e-32 107.6 14.0 0.00025 20.9 0.0 10.3 11 0 0 11 11 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ39908.1 - 6.3e-31 106.4 13.1 8.9e-23 80.3 0.1 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KEZ39908.1 - 4.6e-29 99.0 6.5 2.4e-05 23.9 0.5 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ39908.1 - 1.8e-24 86.0 16.5 0.0044 17.5 0.0 8.1 6 2 2 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ39908.1 - 3.3e-21 73.7 1.9 0.0014 18.7 0.2 9.9 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ39908.1 - 3.6e-21 75.2 16.9 1.6e-07 31.5 0.1 9.1 5 2 4 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ39908.1 - 2.2e-19 68.5 18.6 0.00073 20.2 0.1 9.8 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ39908.1 - 3.8e-17 62.6 22.1 3e-05 24.5 2.4 8.7 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ39908.1 - 1.1e-15 56.9 6.9 0.0019 18.0 0.4 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ39908.1 - 1.1e-10 40.8 11.3 0.28 11.3 0.0 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ39908.1 - 2e-10 40.2 2.0 0.02 14.6 0.0 7.6 7 2 2 9 9 9 3 TPR repeat TPR_9 PF13371.6 KEZ39908.1 - 4.3e-09 36.4 2.2 0.00015 21.8 0.2 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ39908.1 - 2.8e-08 33.6 7.2 1.7 9.5 0.1 7.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ39908.1 - 3.1e-07 30.6 14.0 0.41 11.4 0.1 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ39908.1 - 2.2e-06 27.1 2.9 0.044 13.0 0.0 4.9 3 2 2 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 KEZ39908.1 - 0.0031 17.3 7.9 2.1 8.0 0.4 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 KEZ39908.1 - 0.0088 16.3 0.1 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 Tetratrico peptide repeat Coatomer_E PF04733.14 KEZ39908.1 - 0.04 13.3 0.4 39 3.5 0.0 4.1 5 1 0 6 6 6 0 Coatomer epsilon subunit DUF1347 PF07079.11 KEZ39908.1 - 0.067 11.8 0.0 0.15 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1347) TPR_17 PF13431.6 KEZ39908.1 - 0.078 13.4 3.1 99 3.7 0.0 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat RPN7 PF10602.9 KEZ39908.1 - 0.6 9.8 3.1 7.9 6.2 0.0 3.8 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TEX29 PF15839.5 KEZ39908.1 - 0.62 10.7 1.9 37 5.0 1.9 2.4 1 1 0 1 1 1 0 Testis-expressed sequence 29 protein AAA PF00004.29 KEZ39909.1 - 2.2e-28 99.3 0.0 4.9e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ39909.1 - 4.7e-07 29.5 0.2 1.2e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 KEZ39909.1 - 0.00025 21.4 0.1 0.14 12.4 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 KEZ39909.1 - 0.00067 19.8 0.0 0.0026 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEZ39909.1 - 0.0081 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KEZ39909.1 - 0.011 16.3 0.1 0.038 14.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ39909.1 - 0.011 16.1 0.1 0.039 14.3 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_16 PF13191.6 KEZ39909.1 - 0.011 16.1 0.2 0.081 13.3 0.2 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 KEZ39909.1 - 0.018 15.0 0.1 0.053 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KEZ39909.1 - 0.019 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEZ39909.1 - 0.049 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KEZ39909.1 - 0.11 11.9 0.2 0.27 10.6 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KEZ39909.1 - 0.18 11.5 1.3 0.61 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KEZ39909.1 - 0.19 12.2 1.9 0.38 11.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KEZ39910.1 - 5.2e-30 104.6 0.0 1.6e-16 60.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KEZ39910.1 - 2.3e-14 53.3 6.6 7e-10 38.9 2.2 3.9 3 0 0 3 3 3 2 AAA lid domain AAA_22 PF13401.6 KEZ39910.1 - 3.4e-07 30.6 0.7 0.2 11.9 0.0 4.4 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KEZ39910.1 - 9.8e-07 28.8 0.1 0.046 13.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KEZ39910.1 - 2.1e-06 27.6 0.2 0.00048 19.9 0.0 2.7 2 1 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 KEZ39910.1 - 3.3e-06 26.9 0.1 0.12 12.1 0.0 3.4 3 2 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KEZ39910.1 - 1.1e-05 25.0 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KEZ39910.1 - 1.6e-05 24.7 0.1 0.02 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KEZ39910.1 - 2.4e-05 24.2 10.0 0.35 10.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KEZ39910.1 - 2.6e-05 24.6 0.0 0.65 10.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KEZ39910.1 - 2.9e-05 24.5 0.2 0.59 10.5 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_30 PF13604.6 KEZ39910.1 - 3.6e-05 23.6 0.0 0.5 10.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEZ39910.1 - 0.0002 21.6 2.4 0.53 10.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.6 KEZ39910.1 - 0.00021 21.3 0.0 0.98 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KEZ39910.1 - 0.00042 20.7 0.0 0.33 11.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 KEZ39910.1 - 0.0012 19.0 0.2 1.4 9.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 KEZ39910.1 - 0.0013 18.8 0.0 0.022 14.9 0.0 2.7 3 1 0 3 3 3 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 KEZ39910.1 - 0.002 17.9 0.0 2 8.1 0.0 3.8 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 KEZ39910.1 - 0.0067 16.0 0.0 0.9 9.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 KEZ39910.1 - 0.0093 15.4 0.0 13 5.2 0.0 4.0 5 0 0 5 5 5 0 Bacterial TniB protein AAA_18 PF13238.6 KEZ39910.1 - 0.017 15.7 9.0 0.17 12.4 0.1 3.9 4 1 0 4 4 3 0 AAA domain Torsin PF06309.11 KEZ39910.1 - 0.023 14.8 0.0 0.24 11.5 0.0 2.5 3 0 0 3 3 3 0 Torsin PRK PF00485.18 KEZ39910.1 - 0.078 12.7 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KEZ39910.1 - 0.14 12.1 0.2 49 3.8 0.0 3.1 3 0 0 3 3 3 0 NACHT domain DUF3987 PF13148.6 KEZ39910.1 - 1.2 8.1 0.0 1.2 8.1 0.0 3.7 5 0 0 5 5 4 0 Protein of unknown function (DUF3987) Metallophos PF00149.28 KEZ39911.1 - 2.4e-07 31.5 1.1 5.7e-07 30.2 1.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoLip_ATPase_C PF16212.5 KEZ39912.1 - 1.3e-51 175.8 4.3 1.3e-51 175.8 4.3 1.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEZ39912.1 - 5.6e-16 58.0 0.7 1.2e-15 56.9 0.7 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEZ39912.1 - 2.4e-13 50.9 0.2 3.5e-10 40.5 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEZ39912.1 - 1.7e-08 34.2 0.7 0.00066 19.3 0.0 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 KEZ39912.1 - 0.0001 22.3 0.0 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEZ39912.1 - 0.0027 17.5 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rep_fac_C PF08542.11 KEZ39913.1 - 1.3e-22 80.0 0.0 3.5e-22 78.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KEZ39913.1 - 7.4e-12 45.3 0.0 9.9e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KEZ39913.1 - 8.5e-12 45.6 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEZ39913.1 - 3.1e-07 30.5 0.0 6.6e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ39913.1 - 1.1e-06 29.2 0.0 5.3e-05 23.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KEZ39913.1 - 2.1e-05 24.3 0.0 4.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ39913.1 - 2.8e-05 24.4 0.1 0.055 13.7 0.0 2.6 2 1 1 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ39913.1 - 3.2e-05 23.8 0.0 5.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KEZ39913.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KEZ39913.1 - 0.0011 18.4 0.1 0.0077 15.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KEZ39913.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol3_delta PF06144.13 KEZ39913.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KEZ39913.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KEZ39913.1 - 0.0054 17.0 0.0 0.018 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain NTPase_1 PF03266.15 KEZ39913.1 - 0.0058 16.5 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.6 KEZ39913.1 - 0.0069 16.7 0.1 0.019 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KEZ39913.1 - 0.0088 15.5 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein KTI12 PF08433.10 KEZ39913.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 KEZ39913.1 - 0.021 14.5 0.0 0.066 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEZ39913.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KEZ39913.1 - 0.05 13.4 0.1 0.84 9.4 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 KEZ39913.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEZ39913.1 - 0.07 13.1 0.1 1.9 8.5 0.0 2.7 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEZ39913.1 - 0.073 13.6 0.0 0.13 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.8 KEZ39913.1 - 0.095 12.6 0.2 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III RNA_helicase PF00910.22 KEZ39913.1 - 0.096 13.1 0.0 0.27 11.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KEZ39913.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KEZ39913.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DER1 PF04511.15 KEZ39914.1 - 1.7e-19 70.5 6.2 2e-19 70.2 6.2 1.1 1 0 0 1 1 1 1 Der1-like family CD99L2 PF12301.8 KEZ39915.1 - 0.0068 16.7 0.1 0.066 13.5 0.0 2.4 1 1 1 2 2 2 1 CD99 antigen like protein 2 CcmD PF04995.14 KEZ39915.1 - 0.043 13.9 0.1 0.076 13.1 0.1 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SKG6 PF08693.10 KEZ39915.1 - 0.12 11.8 0.4 0.27 10.7 0.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CN_hydrolase PF00795.22 KEZ39917.1 - 4.3e-15 55.7 0.0 1.1e-14 54.5 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase NOA36 PF06524.12 KEZ39918.1 - 0.48 9.7 3.5 0.27 10.5 0.5 1.9 2 0 0 2 2 2 0 NOA36 protein Hint_2 PF13403.6 KEZ39919.1 - 1.5e-06 28.6 0.2 3.1e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 Hint domain MFS_1 PF07690.16 KEZ39919.1 - 0.00015 20.8 0.8 0.0003 19.8 0.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DLP_helical PF18709.1 KEZ39919.1 - 0.031 13.5 0.1 0.06 12.5 0.1 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain Phage_holin_2_4 PF16082.5 KEZ39919.1 - 0.049 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like BESS PF02944.20 KEZ39919.1 - 0.059 13.2 0.3 11 6.0 0.0 3.0 2 0 0 2 2 2 0 BESS motif DUF2157 PF09925.9 KEZ39919.1 - 0.083 12.7 3.9 2.6 7.8 1.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3040 PF11239.8 KEZ39919.1 - 0.16 12.3 7.6 0.33 11.2 5.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) SNF2_N PF00176.23 KEZ39921.1 - 3.7e-10 39.1 0.0 7.7e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ39921.1 - 1.5e-08 34.9 0.0 4.3e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ39921.1 - 0.0075 16.0 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KEZ39921.1 - 0.01 15.8 0.0 0.082 12.9 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KEZ39921.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SDA1 PF05285.12 KEZ39921.1 - 0.67 9.3 8.0 0.95 8.8 8.0 1.2 1 0 0 1 1 1 0 SDA1 DKCLD PF08068.12 KEZ39922.1 - 1.7e-32 111.2 0.3 2.8e-31 107.4 0.2 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KEZ39922.1 - 4.4e-24 85.6 0.1 5.8e-21 75.4 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KEZ39922.1 - 1.8e-23 82.5 0.8 3.2e-23 81.6 0.8 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KEZ39922.1 - 3.9e-21 74.8 0.2 8e-21 73.8 0.2 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KEZ39922.1 - 0.00045 20.4 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 KEZ39922.1 - 0.6 10.0 9.0 1 9.3 9.0 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AAA_16 PF13191.6 KEZ39923.1 - 3.4e-08 34.0 0.3 1.3e-07 32.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KEZ39923.1 - 0.00027 20.9 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TrwB_AAD_bind PF10412.9 KEZ39923.1 - 0.0017 17.4 0.0 0.3 9.9 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 KEZ39923.1 - 0.0031 16.7 0.0 0.0076 15.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Parvo_NS1 PF01057.17 KEZ39923.1 - 0.0077 15.4 0.0 0.022 13.9 0.0 1.7 1 1 1 2 2 2 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 KEZ39923.1 - 0.012 15.9 0.1 0.056 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 KEZ39923.1 - 0.014 14.3 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase SNF2_N PF00176.23 KEZ39924.1 - 1.5e-36 125.8 0.0 3.3e-22 78.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ39924.1 - 0.00092 19.5 0.0 0.015 15.6 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ39924.1 - 0.18 11.8 0.0 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4448 PF14610.6 KEZ39925.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SAC3_GANP PF03399.16 KEZ39926.1 - 1.1e-95 320.4 0.0 1.6e-95 319.8 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KEZ39926.1 - 0.00047 20.1 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family LTV PF04180.14 KEZ39927.1 - 1.2e-126 423.6 12.7 1.3e-126 423.4 12.7 1.0 1 0 0 1 1 1 1 Low temperature viability protein YL1 PF05764.13 KEZ39927.1 - 0.027 14.6 8.2 0.048 13.8 8.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein MMR_HSR1 PF01926.23 KEZ39928.1 - 1.1e-16 61.0 0.2 4e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ39928.1 - 1.5e-06 27.8 0.2 1.2e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEZ39928.1 - 2e-06 27.8 0.1 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KEZ39928.1 - 0.009 15.4 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KEZ39928.1 - 0.0095 16.0 0.6 0.37 10.8 0.3 2.8 2 1 1 3 3 3 1 Dynamin family Acyl-CoA_dh_1 PF00441.24 KEZ39929.1 - 2.2e-28 99.3 0.4 4.1e-28 98.5 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ39929.1 - 4.4e-20 71.7 0.0 7.8e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEZ39929.1 - 4e-14 53.2 0.1 9e-14 52.1 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEZ39929.1 - 2.4e-12 47.3 1.3 5e-12 46.3 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.12 KEZ39930.1 - 1.5e-15 56.8 0.4 1.5e-15 56.8 0.4 2.4 3 0 0 3 3 3 1 Spo12 family CAML PF14963.6 KEZ39930.1 - 0.028 14.5 0.5 0.034 14.3 0.5 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand MMR_HSR1_Xtn PF16897.5 KEZ39931.1 - 2.4e-35 120.8 2.7 2.8e-35 120.5 0.9 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KEZ39931.1 - 5.8e-20 71.1 0.1 1e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KEZ39931.1 - 7.7e-11 42.1 0.0 2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEZ39931.1 - 0.0004 20.5 0.2 0.00087 19.4 0.0 1.5 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 KEZ39931.1 - 0.00044 19.8 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Baculo_ME53 PF06061.11 KEZ39931.1 - 0.024 13.9 2.1 0.054 12.7 2.1 1.4 1 1 0 1 1 1 0 Baculoviridae ME53 Torus PF16131.5 KEZ39932.1 - 3.7e-45 153.1 0.3 7e-45 152.2 0.0 1.6 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KEZ39932.1 - 6.6e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KEZ39932.1 - 0.00015 21.7 0.3 0.00015 21.7 0.3 1.9 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 KEZ39932.1 - 0.00089 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 KEZ39932.1 - 0.011 15.7 0.5 0.02 14.8 0.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEZ39932.1 - 0.54 10.1 2.2 1.2 9.0 2.2 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger Cut12 PF11500.8 KEZ39933.1 - 2.8e-47 160.3 17.2 2.8e-47 160.3 17.2 3.7 3 1 2 5 5 5 1 Spindle pole body formation-associated protein UreF PF01730.16 KEZ39933.1 - 2.4e-23 83.2 2.3 2.4e-23 83.2 0.1 2.1 2 0 0 2 2 2 1 UreF TPR_MLP1_2 PF07926.12 KEZ39933.1 - 0.00091 19.3 10.3 0.00091 19.3 10.3 3.8 5 0 0 5 5 5 1 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 KEZ39933.1 - 0.0041 17.6 0.9 0.0041 17.6 0.9 3.9 2 2 1 3 3 3 1 Spectrin repeat Fez1 PF06818.15 KEZ39933.1 - 0.02 15.4 39.8 0.037 14.5 3.0 3.3 2 1 1 3 3 3 0 Fez1 NPR3 PF03666.13 KEZ39933.1 - 0.15 10.8 10.5 0.15 10.8 8.7 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2730 PF10805.8 KEZ39933.1 - 6 7.0 12.0 1 9.5 1.3 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) PBP1_TM PF14812.6 KEZ39933.1 - 9.4 6.7 17.2 1.8 9.0 10.5 3.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 KEZ39934.1 - 9.4e-67 225.1 0.0 4.1e-32 111.6 0.0 3.5 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KEZ39934.1 - 7.5e-54 183.0 0.0 7.5e-54 183.0 0.0 2.5 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KEZ39934.1 - 6.1e-47 160.1 0.0 3.4e-20 72.4 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KEZ39934.1 - 5.1e-15 55.5 1.0 6.9e-15 55.1 0.0 1.7 2 0 0 2 2 1 1 Histidyl-tRNA synthetase RWD PF05773.22 KEZ39934.1 - 2.4e-10 40.7 0.1 5.1e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KEZ39934.1 - 1.8e-07 31.3 5.2 0.0044 17.0 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ39934.1 - 3.5e-06 26.1 3.3 0.0026 16.6 0.0 2.9 3 0 0 3 3 3 2 Fungal protein kinase Kinase-like PF14531.6 KEZ39934.1 - 0.0011 18.3 0.0 0.013 14.8 0.0 2.4 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 KEZ39934.1 - 0.0066 16.0 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KEZ39934.1 - 0.01 15.2 3.4 0.54 9.6 0.0 2.9 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KEZ39934.1 - 0.033 13.8 4.6 0.61 9.7 0.0 3.5 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 UQ_con PF00179.26 KEZ39935.1 - 6.8e-33 113.3 0.0 8.7e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ39935.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KEZ39935.1 - 0.075 13.3 0.4 0.15 12.4 0.4 1.9 1 1 0 1 1 1 0 RWD domain DUF812 PF05667.11 KEZ39936.1 - 0.049 12.5 1.4 0.084 11.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UBA_4 PF14555.6 KEZ39936.1 - 0.062 13.1 0.4 0.062 13.1 0.4 1.9 2 0 0 2 2 2 0 UBA-like domain Acetyltransf_11 PF13720.6 KEZ39936.1 - 0.13 12.7 0.0 10 6.6 0.1 3.3 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DnaJ_C PF01556.18 KEZ39937.1 - 1.4e-36 125.8 0.7 1.9e-36 125.4 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ39937.1 - 4e-27 94.1 1.3 7e-27 93.3 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain HAD_2 PF13419.6 KEZ39938.1 - 1.6e-20 73.9 0.0 2e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ39938.1 - 2e-08 34.8 0.1 1.5e-07 31.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ39938.1 - 8.7e-05 22.5 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KEZ39938.1 - 0.0004 20.2 0.0 0.014 15.2 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KEZ39938.1 - 0.095 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Endomucin PF07010.12 KEZ39939.1 - 0.26 11.2 0.9 0.46 10.4 0.9 1.3 1 0 0 1 1 1 0 Endomucin Rod_cone_degen PF15201.6 KEZ39939.1 - 1.1 9.4 0.1 1.1 9.4 0.1 2.7 3 0 0 3 3 3 0 Progressive rod-cone degeneration FH2 PF02181.23 KEZ39940.1 - 9.9e-86 288.2 5.0 9.9e-86 288.2 5.0 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KEZ39940.1 - 8.3e-64 214.6 0.1 4.4e-63 212.3 0.0 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KEZ39940.1 - 8.6e-51 172.3 2.8 3.9e-50 170.2 2.3 2.3 1 1 1 2 2 2 1 Diaphanous FH3 Domain Rx_N PF18052.1 KEZ39940.1 - 1.7 9.0 7.9 0.94 9.8 2.7 3.3 2 0 0 2 2 2 0 Rx N-terminal domain DUF4048 PF13257.6 KEZ39941.1 - 3.3e-11 43.5 11.7 3.3e-11 43.5 11.7 3.6 2 2 1 3 3 3 1 Domain of unknown function (DUF4048) DNA_ligase_A_N PF04675.14 KEZ39942.1 - 5e-18 66.0 0.0 1.1e-17 64.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 KEZ39942.1 - 0.00019 21.2 0.0 0.16 11.6 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain Pkinase PF00069.25 KEZ39943.1 - 8.4e-69 231.9 0.0 1.4e-68 231.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39943.1 - 1e-34 120.0 0.0 2.7e-34 118.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ39943.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEZ39943.1 - 0.0049 16.2 0.2 0.01 15.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEZ39943.1 - 0.038 12.9 0.3 0.11 11.4 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KEZ39943.1 - 0.57 8.9 0.0 0.57 8.9 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase Abhydrolase_1 PF00561.20 KEZ39944.1 - 1.3e-13 51.2 0.0 8.1e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ39944.1 - 3e-09 36.5 0.0 1.4e-07 31.0 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 IF4E PF01652.18 KEZ39946.1 - 2.5e-54 183.4 0.1 3.4e-54 183.0 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Utp13 PF08625.11 KEZ39947.1 - 6.9e-52 175.1 1.5 1.1e-51 174.5 1.5 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KEZ39947.1 - 3.2e-49 163.9 25.8 5.4e-05 23.9 0.5 11.9 12 2 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39947.1 - 3.6e-11 43.2 3.5 0.091 13.1 0.1 8.3 7 2 2 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ39947.1 - 5.4e-06 25.3 9.2 0.23 10.1 0.0 6.2 4 3 3 7 7 7 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEZ39947.1 - 0.00032 19.6 8.8 0.46 9.2 0.0 5.8 5 2 1 7 7 7 2 Nup133 N terminal like Malic_M PF03949.15 KEZ39949.1 - 4.6e-93 311.2 0.0 6e-93 310.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KEZ39949.1 - 1.9e-69 233.1 0.0 3.1e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RNB PF00773.19 KEZ39950.1 - 1.4e-78 264.5 0.0 2.3e-78 263.8 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KEZ39950.1 - 5.7e-26 90.3 0.0 1.3e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KEZ39950.1 - 5.5e-24 84.3 0.0 2e-23 82.5 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KEZ39950.1 - 1.6e-06 28.2 0.0 0.0094 16.1 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KEZ39950.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Rrp44-like cold shock domain DUF4239 PF14023.6 KEZ39950.1 - 0.13 12.0 0.4 0.3 10.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) NPR3 PF03666.13 KEZ39950.1 - 1.3 7.8 8.7 0.16 10.7 0.4 2.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ferritin_2 PF13668.6 KEZ39951.1 - 1.8e-39 135.0 1.5 3.1e-39 134.3 1.5 1.4 1 0 0 1 1 1 1 Ferritin-like domain DIOX_N PF14226.6 KEZ39952.1 - 8.8e-17 61.9 0.0 1.4e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ39952.1 - 9.2e-13 48.6 0.0 2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 KEZ39953.1 - 5.8e-68 228.7 0.0 7.9e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KEZ39953.1 - 1.4e-32 111.9 0.0 3e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KEZ39953.1 - 1.6e-06 28.5 0.0 1.6e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain Pmp3 PF01679.17 KEZ39954.1 - 2.3e-09 37.3 16.0 2.3e-07 30.9 16.0 2.1 1 1 0 1 1 1 1 Proteolipid membrane potential modulator zf-RanBP PF00641.18 KEZ39955.1 - 1.1e-18 66.2 12.9 4.2e-11 42.0 1.4 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KEZ39955.1 - 3.2e-08 33.3 0.0 6.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KEZ39955.1 - 1.3e-05 25.8 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CAF1C_H4-bd PF12265.8 KEZ39956.1 - 1.6e-27 95.5 0.5 9.9e-27 93.0 0.3 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KEZ39956.1 - 1.6e-25 88.8 8.9 2.8e-06 27.9 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ39956.1 - 4e-06 27.0 0.3 0.29 11.5 0.0 4.6 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Leader_Erm PF08253.11 KEZ39956.1 - 0.49 10.8 2.5 10 6.7 0.4 2.6 2 0 0 2 2 2 0 Erm Leader peptide XRN_M PF17846.1 KEZ39957.1 - 2.5e-99 333.2 7.1 3.9e-99 332.6 7.1 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KEZ39957.1 - 4.6e-96 320.9 0.0 7e-96 320.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KEZ39957.1 - 2.8e-70 236.0 0.0 5.1e-70 235.1 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KEZ39957.1 - 2.7e-34 117.2 0.1 7.2e-34 115.9 0.1 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KEZ39957.1 - 2.8e-21 75.4 0.1 5.4e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KEZ39957.1 - 0.00052 20.0 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SPC22 PF04573.12 KEZ39958.1 - 1.1e-39 135.7 0.2 1.5e-38 131.9 0.2 1.9 1 1 0 1 1 1 1 Signal peptidase subunit Cohesin_load PF10345.9 KEZ39960.1 - 2.1e-129 432.7 3.0 3.1e-129 432.1 3.0 1.2 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 KEZ39960.1 - 9.9 6.5 10.8 4 7.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat HDA2-3 PF11496.8 KEZ39961.1 - 1.7e-07 30.7 0.6 8.9e-06 25.1 0.6 2.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF3141 PF11339.8 KEZ39961.1 - 0.021 13.3 0.4 0.035 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Shugoshin_N PF07558.11 KEZ39961.1 - 0.025 14.5 1.9 4.3 7.3 0.2 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Phage_HK97_TLTM PF06120.11 KEZ39961.1 - 0.42 9.8 18.9 0.37 9.9 2.5 2.6 2 0 0 2 2 2 0 Tail length tape measure protein Spc7 PF08317.11 KEZ39961.1 - 0.97 8.3 25.8 0.85 8.4 10.4 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein BRE1 PF08647.11 KEZ39961.1 - 1.3 9.1 23.4 0.038 14.1 8.2 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 KEZ39961.1 - 2.3 8.7 7.7 17 5.9 0.2 4.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Sec34 PF04136.15 KEZ39961.1 - 8.2 6.3 10.9 0.81 9.6 3.3 2.4 2 0 0 2 2 2 0 Sec34-like family Laminin_II PF06009.12 KEZ39961.1 - 9 6.3 17.9 0.45 10.5 4.5 3.2 2 1 1 3 3 3 0 Laminin Domain II COX5A PF02284.16 KEZ39962.1 - 2.5e-39 133.4 1.3 3.6e-39 132.9 1.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Goodbye PF17109.5 KEZ39962.1 - 0.011 16.2 0.3 0.016 15.7 0.3 1.3 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain SF3A3 PF16837.5 KEZ39962.1 - 0.065 13.8 0.1 0.095 13.2 0.1 1.4 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 UPF0449 PF15136.6 KEZ39962.1 - 0.12 12.9 1.2 1.8 9.1 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 ELO PF01151.18 KEZ39963.1 - 2.5e-63 213.9 15.3 3e-63 213.7 15.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.7 KEZ39964.1 - 0.00012 21.9 0.8 0.00012 21.9 0.8 2.2 2 0 0 2 2 2 1 F-box-like Glycogen_syn PF05693.13 KEZ39965.1 - 0 1129.9 0.0 0 1129.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 KEZ39965.1 - 1.5e-05 25.1 1.1 3.1e-05 24.0 0.4 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KEZ39965.1 - 4.3e-05 23.1 0.0 0.0031 17.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ39965.1 - 5.7e-05 23.6 0.0 0.035 14.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KEZ39965.1 - 6e-05 22.9 0.1 0.00012 21.9 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 KEZ39965.1 - 0.00054 20.4 0.1 0.0024 18.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Hid1 PF12722.7 KEZ39966.1 - 2.6e-293 975.2 0.0 3e-293 975.0 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KEZ39966.1 - 4.2e-96 322.8 0.0 5e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 KEZ39966.1 - 0.066 12.2 2.2 0.11 11.4 2.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 KEZ39966.1 - 0.17 11.2 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPCC PF08058.11 KEZ39968.1 - 1.4e-25 89.9 0.0 1.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component DUF3684 PF12449.8 KEZ39969.1 - 0 1346.0 0.0 0 1345.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KEZ39969.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 KEZ39969.1 - 0.14 12.2 1.8 6 6.9 0.2 2.6 2 0 0 2 2 2 0 WLM domain YdfA_immunity PF12127.8 KEZ39969.1 - 2.5 7.1 5.4 9.8 5.1 0.3 2.4 2 0 0 2 2 2 0 SigmaW regulon antibacterial MMtag PF10159.9 KEZ39970.1 - 6.7e-31 106.4 2.4 6.7e-31 106.4 2.4 1.9 2 0 0 2 2 2 1 Multiple myeloma tumor-associated RSB_motif PF16294.5 KEZ39970.1 - 5.2 7.4 15.5 11 6.3 8.6 2.4 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif FKBP_C PF00254.28 KEZ39971.1 - 4.1e-30 103.9 0.0 1.1e-29 102.6 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KEZ39971.1 - 3.5e-28 98.2 8.1 3.5e-28 98.2 8.1 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain AAA_11 PF13086.6 KEZ39971.1 - 0.011 15.5 1.7 0.011 15.5 1.7 2.2 2 0 0 2 2 2 0 AAA domain Glyco_trans_2_3 PF13632.6 KEZ39972.1 - 1.2e-19 71.0 0.4 1.2e-19 71.0 0.4 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 SR-25 PF10500.9 KEZ39972.1 - 0.54 9.8 7.3 0.87 9.2 7.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FmiP_Thoc5 PF09766.9 KEZ39973.1 - 4.5e-32 111.7 13.2 4.5e-32 111.7 13.2 1.6 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 KEZ39973.1 - 0.018 15.1 4.7 0.018 15.1 4.7 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF3958 PF13125.6 KEZ39973.1 - 0.096 12.9 11.0 0.67 10.2 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) Mod_r PF07200.13 KEZ39973.1 - 0.45 10.6 12.2 0.16 12.1 3.3 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Casc1_N PF15927.5 KEZ39973.1 - 0.68 9.6 16.1 0.041 13.6 9.3 2.0 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus YabA PF06156.13 KEZ39973.1 - 1.3 9.7 6.7 8.4 7.1 1.4 2.3 2 0 0 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 KEZ39973.1 - 3.5 7.7 16.4 4.5 7.3 4.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 KEZ39973.1 - 5.1 7.5 16.7 3.6 8.0 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF349 PF03993.12 KEZ39973.1 - 5.2 7.4 14.0 0.49 10.7 8.1 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) HlyIII PF03006.20 KEZ39974.1 - 1.1e-61 208.5 17.7 1.3e-61 208.2 17.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Planc_extracel PF07595.12 KEZ39974.1 - 0.71 9.8 4.5 0.76 9.7 0.1 2.7 2 0 0 2 2 2 0 Planctomycete extracellular Pkinase PF00069.25 KEZ39976.1 - 3.4e-30 105.3 0.0 3.2e-29 102.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39976.1 - 3.6e-14 52.7 0.0 6.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf_CCCH_4 PF18345.1 KEZ39976.1 - 0.00036 20.5 2.4 0.001 19.1 2.4 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KEZ39976.1 - 0.00045 20.0 1.5 0.0012 18.7 1.5 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEZ39976.1 - 0.0014 18.4 3.0 0.0034 17.2 3.0 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Pox_ser-thr_kin PF05445.11 KEZ39976.1 - 0.038 13.0 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KEZ39976.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RabGAP-TBC PF00566.18 KEZ39977.1 - 5.2e-33 114.5 0.1 1.2e-26 93.7 0.0 3.1 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.20 KEZ39978.1 - 1.2e-108 363.3 21.5 1.6e-108 362.9 21.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEZ39978.1 - 1.3e-06 28.1 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KEZ39978.1 - 0.00048 20.5 2.9 0.00048 20.5 2.9 3.7 2 2 2 4 4 4 1 Molybdate transporter of MFS superfamily 7tm_2 PF00002.24 KEZ39979.1 - 3.1e-06 26.7 15.9 3.4e-06 26.5 13.5 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KEZ39979.1 - 0.0011 18.2 8.3 0.0021 17.2 8.3 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Vma12 PF11712.8 KEZ39979.1 - 2.6 8.1 6.1 2.8 8.0 0.0 3.1 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DC_STAMP PF07782.13 KEZ39979.1 - 3.7 7.3 7.6 0.61 9.9 0.2 2.9 2 2 0 2 2 2 0 DC-STAMP-like protein Abhydrolase_6 PF12697.7 KEZ39980.1 - 2.6e-22 80.5 3.8 2.6e-22 80.5 3.8 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ39980.1 - 3.4e-10 40.0 0.1 1.9e-09 37.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ39980.1 - 1.2e-07 31.2 0.2 1.9e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KEZ39980.1 - 6.5e-05 23.2 0.1 0.00011 22.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 KEZ39980.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PAF-AH_p_II PF03403.13 KEZ39980.1 - 0.092 11.2 0.2 3.1 6.2 0.1 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 KEZ39980.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KEZ39980.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) TRP PF06011.12 KEZ39981.1 - 5.9e-145 483.2 17.1 8e-145 482.8 17.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEZ39981.1 - 3.3e-38 131.2 1.7 5.5e-38 130.5 1.7 1.4 1 0 0 1 1 1 1 ML-like domain DUF5103 PF17116.5 KEZ39981.1 - 0.073 12.3 0.7 0.12 11.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) SieB PF14163.6 KEZ39981.1 - 3.5 7.1 9.5 0.56 9.7 0.2 3.1 3 0 0 3 3 3 0 Super-infection exclusion protein B Asn_synthase PF00733.21 KEZ39982.1 - 3.7e-20 72.9 0.6 4.1e-09 36.6 0.2 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KEZ39982.1 - 2.1e-07 30.9 0.0 1.5e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KEZ39982.1 - 0.00066 19.9 0.0 0.002 18.3 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain PAPS_reduct PF01507.19 KEZ39982.1 - 0.21 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family EcsB PF05975.12 KEZ39983.1 - 0.15 10.9 8.3 0.3 9.9 8.3 1.4 1 1 0 1 1 1 0 Bacterial ABC transporter protein EcsB zf-C2H2 PF00096.26 KEZ39984.1 - 0.0083 16.5 2.7 0.0083 16.5 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type CSN5_C PF18323.1 KEZ39984.1 - 0.088 13.7 0.3 0.36 11.8 0.0 2.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain zf-C2H2_aberr PF17017.5 KEZ39984.1 - 1.5 9.0 6.3 7 6.8 3.3 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger TAP_C PF03943.13 KEZ39985.1 - 2.3e-15 55.9 0.1 4.2e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 KEZ39985.1 - 2e-06 28.4 0.0 5.2e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 KEZ39985.1 - 4.8e-05 22.9 0.0 8.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KEZ39985.1 - 0.00018 21.8 1.3 0.061 13.8 0.7 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 KEZ39985.1 - 0.00068 19.4 0.0 0.0042 16.9 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif LRR_8 PF13855.6 KEZ39985.1 - 0.0029 17.3 0.6 0.011 15.4 0.6 2.1 1 1 0 1 1 1 1 Leucine rich repeat Fes1 PF08609.10 KEZ39985.1 - 0.086 13.7 2.9 3.5 8.6 1.1 3.0 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 Pkinase PF00069.25 KEZ39986.1 - 1.3e-16 60.8 0.0 3.7e-14 52.7 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ39986.1 - 1.5e-05 24.4 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Peroxidase_2 PF01328.17 KEZ39987.1 - 2.6e-37 129.1 0.7 2.1e-36 126.2 0.7 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 Ank_4 PF13637.6 KEZ39988.1 - 9.5e-29 99.4 9.1 1.6e-08 35.0 0.0 8.3 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ39988.1 - 6.4e-26 90.8 0.9 5.9e-09 36.4 0.0 5.0 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ39988.1 - 2.8e-19 67.2 12.4 0.1 13.2 0.1 10.5 12 0 0 12 12 12 6 Ankyrin repeat Clr5 PF14420.6 KEZ39988.1 - 8.8e-10 38.7 0.1 2.1e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 KEZ39988.1 - 3.9e-08 33.4 12.3 13 6.4 0.1 9.1 10 1 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.6 KEZ39988.1 - 5.6e-07 29.7 8.4 0.027 14.8 0.0 6.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) HET PF06985.11 KEZ39991.1 - 1e-28 100.5 0.0 2.3e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EccE PF11203.8 KEZ39991.1 - 0.057 13.7 0.1 0.77 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE YtxH PF12732.7 KEZ39992.1 - 0.0017 18.9 11.2 0.44 11.1 2.8 3.6 1 1 2 3 3 3 2 YtxH-like protein Senescence PF06911.12 KEZ39992.1 - 0.0055 17.0 16.4 0.027 14.8 16.4 2.0 1 1 0 1 1 1 1 Senescence-associated protein Phasin_2 PF09361.10 KEZ39992.1 - 0.0079 16.4 1.4 0.11 12.8 1.7 2.2 1 1 1 2 2 2 1 Phasin protein ApoLp-III PF07464.11 KEZ39992.1 - 0.011 15.8 1.5 0.11 12.6 0.6 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CsbD PF05532.12 KEZ39992.1 - 0.017 15.0 5.1 0.017 15.0 5.1 2.9 2 1 1 3 3 3 0 CsbD-like POTRA_3 PF17287.2 KEZ39992.1 - 0.025 14.0 0.1 0.056 12.9 0.1 1.5 1 0 0 1 1 1 0 POTRA domain DUF883 PF05957.13 KEZ39992.1 - 0.19 12.4 6.3 3.4 8.3 3.0 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 KEZ39992.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.6 KEZ39992.1 - 0.35 11.2 31.7 0.26 11.6 13.3 3.0 1 1 1 2 2 2 0 MT0933-like antitoxin protein HTH_15 PF12324.8 KEZ39992.1 - 0.65 10.0 5.8 2.3 8.2 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase DUF948 PF06103.11 KEZ39992.1 - 0.68 10.2 11.3 2.9 8.2 1.5 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Alanine_zipper PF11839.8 KEZ39992.1 - 0.82 10.1 7.8 2.2 8.7 7.8 1.8 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Perilipin PF03036.16 KEZ39992.1 - 1.5 7.7 10.2 0.47 9.4 7.1 1.6 1 1 1 2 2 2 0 Perilipin family CtnDOT_TraJ PF07863.11 KEZ39992.1 - 3.3 8.4 6.0 19 6.0 0.0 3.3 1 1 2 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon ISG65-75 PF11727.8 KEZ39992.1 - 5.3 6.2 7.7 12 5.0 4.4 1.8 1 1 1 2 2 2 0 Invariant surface glycoprotein EspB PF05802.11 KEZ39992.1 - 5.5 6.9 22.3 33 4.4 22.3 2.2 1 1 0 1 1 1 0 Enterobacterial EspB protein ATP_bind_1 PF03029.17 KEZ39993.1 - 8e-68 228.8 0.0 2.2e-67 227.4 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KEZ39993.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KEZ39993.1 - 0.00041 20.2 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 KEZ39993.1 - 0.00044 20.3 0.0 0.0015 18.6 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KEZ39993.1 - 0.00081 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ39993.1 - 0.0015 19.0 0.2 0.0078 16.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ39993.1 - 0.0042 17.4 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEZ39993.1 - 0.0047 17.3 0.0 0.0089 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KEZ39993.1 - 0.012 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KEZ39993.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KEZ39993.1 - 0.029 14.9 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 KEZ39993.1 - 0.035 13.8 0.0 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase GTP_EFTU PF00009.27 KEZ39993.1 - 0.048 13.2 0.1 1.5 8.3 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEZ39993.1 - 0.074 13.1 0.0 0.29 11.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 KEZ39993.1 - 0.077 12.9 0.0 9 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KEZ39993.1 - 0.078 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Hpr_kinase_C PF07475.12 KEZ39993.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_29 PF13555.6 KEZ39993.1 - 0.085 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ39993.1 - 0.091 12.7 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 KEZ39993.1 - 0.093 12.5 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 KEZ39993.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.14 KEZ39993.1 - 0.1 11.8 0.0 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 KEZ39993.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 KEZ39993.1 - 0.12 12.7 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEZ39993.1 - 0.15 12.4 0.0 0.75 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 KEZ39993.1 - 0.16 11.8 0.2 1 9.2 0.0 2.0 2 0 0 2 2 2 0 NTPase PPV_E1_C PF00519.17 KEZ39993.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase S-AdoMet_synt_C PF02773.16 KEZ39994.1 - 2.7e-66 221.7 0.4 5.6e-66 220.7 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KEZ39994.1 - 3e-44 150.1 0.0 6.8e-44 149.0 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KEZ39994.1 - 1.5e-42 144.3 0.3 3.5e-42 143.1 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain THF_DHG_CYH PF00763.23 KEZ39996.1 - 3.1e-25 88.7 0.1 4.5e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KEZ39996.1 - 2.8e-14 52.7 0.0 1.5e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ank_2 PF12796.7 KEZ39997.1 - 1.1e-94 311.1 0.0 8.8e-16 58.3 0.0 8.4 2 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ39997.1 - 4.6e-81 266.2 2.5 2e-10 41.0 0.0 11.3 9 3 3 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ39997.1 - 6.3e-70 222.8 0.9 0.00011 22.3 0.0 17.8 18 0 0 18 18 18 15 Ankyrin repeat Ank PF00023.30 KEZ39997.1 - 1.1e-66 218.6 1.0 0.00089 19.6 0.0 17.2 17 0 0 17 17 17 15 Ankyrin repeat Ank_5 PF13857.6 KEZ39997.1 - 3.2e-58 193.0 8.2 4.4e-08 33.2 0.1 13.6 5 2 7 13 13 13 12 Ankyrin repeats (many copies) INTS5_C PF14838.6 KEZ39997.1 - 0.086 11.5 0.1 0.35 9.4 0.0 2.1 3 0 0 3 3 3 0 Integrator complex subunit 5 C-terminus VWA_3_C PF18571.1 KEZ39997.1 - 0.36 10.7 11.1 1.2e+02 2.6 0.0 7.7 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain MMS19_N PF14500.6 KEZ39998.1 - 7e-51 173.3 0.2 2.5e-50 171.5 0.2 2.0 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KEZ39998.1 - 1.3e-15 57.4 1.1 7.8e-15 54.9 0.0 2.8 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Ipi1_N PF12333.8 KEZ39998.1 - 0.096 13.3 0.4 1.3 9.6 0.0 3.0 3 1 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation SPC25 PF06703.11 KEZ39999.1 - 5e-54 182.5 0.0 6e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 KEZ40000.1 - 6.9e-51 172.3 0.7 1e-50 171.8 0.7 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RNA_pol_Rbc25 PF08292.12 KEZ40001.1 - 2.6e-28 98.8 0.6 2.5e-27 95.7 0.6 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KEZ40001.1 - 1.3e-08 35.1 0.0 1.8e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 KEZ40002.1 - 1.9e-08 34.0 1.2 1.9e-08 34.0 1.2 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KEZ40002.1 - 0.065 13.3 7.0 0.13 12.4 7.0 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KEZ40002.1 - 0.2 11.6 5.8 0.4 10.7 5.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ArnB_C PF18677.1 KEZ40002.1 - 0.56 10.3 7.3 1 9.5 7.3 1.4 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain CHD5 PF04420.14 KEZ40002.1 - 4.8 7.0 5.3 8.4 6.2 5.3 1.3 1 0 0 1 1 1 0 CHD5-like protein Prot_ATP_OB_N PF17758.1 KEZ40003.1 - 0.00081 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain PRY PF13765.6 KEZ40003.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 SPRY-associated domain SPT2 PF08243.11 KEZ40004.1 - 8.3e-11 42.4 27.6 2.2e-08 34.6 27.6 2.4 1 1 0 1 1 1 1 SPT2 chromatin protein CDC45 PF02724.14 KEZ40005.1 - 0.19 10.0 19.7 0.28 9.4 5.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.12 KEZ40005.1 - 4.6 7.2 12.3 0.75 9.8 2.2 2.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ofd1_CTDD PF10637.9 KEZ40006.1 - 2e-95 319.0 0.0 2.5e-90 302.3 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KEZ40006.1 - 4.8e-26 91.3 0.0 1.8e-25 89.4 0.0 2.0 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KEZ40006.1 - 1.8e-12 48.0 0.0 3.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sporozoite_P67 PF05642.11 KEZ40006.1 - 0.44 8.6 5.8 0.69 7.9 5.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aminotran_5 PF00266.19 KEZ40007.1 - 7.4e-52 176.5 0.0 1.2e-51 175.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KEZ40007.1 - 9.5e-11 41.5 0.0 1.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ40007.1 - 1.4e-05 23.8 0.0 2.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ40007.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribul_P_3_epim PF00834.19 KEZ40008.1 - 1.4e-62 210.7 0.0 7.5e-62 208.2 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 KEZ40008.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 KEZ40008.1 - 0.035 13.7 0.1 0.07 12.7 0.0 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Pkinase PF00069.25 KEZ40009.1 - 6.2e-68 229.0 0.0 1e-67 228.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40009.1 - 2.3e-38 131.9 0.0 4e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ40009.1 - 3.6e-05 23.2 0.0 7.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ40009.1 - 0.0002 21.4 0.0 0.00048 20.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ40009.1 - 0.001 17.9 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KEZ40009.1 - 0.018 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 AAA PF00004.29 KEZ40010.1 - 3.5e-50 169.8 0.0 2.9e-42 144.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ40010.1 - 5.7e-05 23.6 0.2 0.016 15.6 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KEZ40010.1 - 0.00013 21.7 0.0 0.0004 20.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 KEZ40010.1 - 0.00017 21.3 1.0 0.82 9.5 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain Parvo_NS1 PF01057.17 KEZ40010.1 - 0.00081 18.6 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 KEZ40010.1 - 0.0033 17.6 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEZ40010.1 - 0.0078 16.5 0.0 0.035 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEZ40010.1 - 0.0083 15.9 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KEZ40010.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 KEZ40010.1 - 0.012 16.0 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KEZ40010.1 - 0.014 15.0 0.0 0.043 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KEZ40010.1 - 0.028 13.8 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KEZ40010.1 - 0.037 13.4 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 KEZ40010.1 - 0.038 14.0 0.1 0.22 11.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ40010.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Vps4_C PF09336.10 KEZ40010.1 - 0.058 13.4 0.0 0.31 11.1 0.0 2.3 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 KEZ40010.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KEZ40010.1 - 0.095 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ40010.1 - 0.096 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KEZ40010.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 KEZ40010.1 - 0.11 13.0 0.0 0.4 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ40010.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ40010.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KEZ40010.1 - 0.18 11.5 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Peptidase_M3 PF01432.20 KEZ40011.1 - 9.5e-81 272.4 0.2 2.8e-49 168.6 0.2 2.3 1 1 1 2 2 2 2 Peptidase family M3 DUF4399 PF14347.6 KEZ40011.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Methyltransf_23 PF13489.6 KEZ40012.1 - 1.9e-10 40.8 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40012.1 - 1.2e-09 38.7 0.0 2.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40012.1 - 1.2e-07 32.3 0.0 3.2e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ40012.1 - 0.0018 19.0 0.0 0.0043 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KEZ40012.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KEZ40012.1 - 0.011 15.3 0.0 0.024 14.1 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_31 PF13847.6 KEZ40012.1 - 0.049 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ40012.1 - 0.057 12.7 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ40012.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KEZ40012.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Pkinase PF00069.25 KEZ40013.1 - 3.6e-63 213.4 0.0 4.9e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40013.1 - 1.1e-36 126.4 0.0 1.5e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEZ40013.1 - 3.5e-05 23.2 0.1 5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEZ40013.1 - 3.9e-05 23.1 0.0 7.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAN_1 PF00024.26 KEZ40013.1 - 0.012 15.6 3.1 0.023 14.6 3.1 1.4 1 0 0 1 1 1 0 PAN domain APH PF01636.23 KEZ40013.1 - 0.045 13.7 0.0 0.24 11.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family MANEC PF07502.14 KEZ40013.1 - 0.05 13.9 1.7 0.096 13.0 1.7 1.4 1 0 0 1 1 1 0 MANEC domain Pkinase_fungal PF17667.1 KEZ40013.1 - 0.079 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PAN_4 PF14295.6 KEZ40013.1 - 0.27 11.2 3.9 0.56 10.2 3.9 1.5 1 0 0 1 1 1 0 PAN domain OTT_1508_deam PF14441.6 KEZ40014.1 - 1.1e-16 60.6 2.2 2.5e-16 59.4 2.2 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Fungal_trans PF04082.18 KEZ40015.1 - 1.4e-26 93.1 0.0 2.2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARP PF00644.20 KEZ40016.1 - 1.3e-54 184.8 0.0 1.3e-54 184.8 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KEZ40016.1 - 1.5e-45 154.7 0.0 3.6e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KEZ40016.1 - 7.6e-25 86.8 1.3 2.1e-24 85.4 1.3 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KEZ40016.1 - 1.1e-09 38.5 0.0 2.5e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KEZ40016.1 - 2.6e-07 30.5 0.1 5.2e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF4366 PF14283.6 KEZ40016.1 - 0.28 11.2 4.5 3.4 7.7 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) FAD_binding_4 PF01565.23 KEZ40017.1 - 2.5e-26 92.1 0.2 4.2e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3632 PF12311.8 KEZ40018.1 - 2.4e-38 132.3 5.0 3e-38 132.0 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.20 KEZ40019.1 - 5.7e-10 39.8 0.0 7.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ribonuclease MFS_1 PF07690.16 KEZ40020.1 - 1.2e-29 103.3 44.2 2.2e-29 102.5 41.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 KEZ40020.1 - 0.048 14.0 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Caleosin PF05042.13 KEZ40021.1 - 8.9e-65 217.7 0.4 1.1e-64 217.4 0.4 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 KEZ40021.1 - 4e-05 23.2 2.9 0.014 15.3 0.9 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KEZ40021.1 - 0.0003 20.1 4.9 0.0026 17.2 0.3 3.3 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 KEZ40021.1 - 0.023 15.1 0.7 1.8 9.1 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 KEZ40021.1 - 0.28 10.8 3.6 4.8 6.8 0.6 3.1 3 0 0 3 3 3 0 EF hand p450 PF00067.22 KEZ40023.1 - 4e-39 134.6 0.0 2e-22 79.6 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 DUF4633 PF15464.6 KEZ40023.1 - 0.12 12.6 0.3 0.33 11.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Trp_DMAT PF11991.8 KEZ40024.1 - 3.4e-52 178.0 0.0 4.6e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Ferric_reduct PF01794.19 KEZ40025.1 - 5.8e-24 84.6 16.2 1.3e-23 83.5 16.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEZ40025.1 - 6.9e-07 29.5 1.4 0.0017 18.5 0.0 2.3 1 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEZ40025.1 - 2e-05 24.6 0.0 0.0071 16.4 0.0 2.6 2 1 0 2 2 2 2 FAD-binding domain XPA_N PF01286.18 KEZ40027.1 - 0.2 11.8 0.4 0.2 11.8 0.4 2.2 2 0 0 2 2 2 0 XPA protein N-terminal MFS_1 PF07690.16 KEZ40028.1 - 2.3e-36 125.5 24.6 3.4e-36 124.9 24.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ40028.1 - 0.00021 20.7 3.6 0.00021 20.7 3.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Phage_holin_2_4 PF16082.5 KEZ40028.1 - 0.054 13.2 5.1 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 KEZ40029.1 - 3.2e-29 102.0 61.0 1e-22 80.5 40.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ40029.1 - 3.5e-05 22.8 23.0 0.034 13.0 4.9 3.3 3 0 0 3 3 3 3 MFS_1 like family Fungal_trans PF04082.18 KEZ40030.1 - 1.3e-09 37.5 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AbiTii PF18864.1 KEZ40030.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AbiTii Ig_mannosidase PF17753.1 KEZ40030.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Ig-fold domain GMC_oxred_C PF05199.13 KEZ40031.1 - 3.1e-31 108.8 0.0 5.2e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KEZ40031.1 - 2.1e-26 93.0 0.0 3.7e-19 69.2 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.6 KEZ40031.1 - 2e-05 24.7 0.0 6.6e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ40031.1 - 0.00017 20.9 0.0 0.00068 19.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ40031.1 - 0.016 14.3 0.2 0.039 13.0 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KEZ40031.1 - 0.023 14.0 0.5 0.033 13.4 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KEZ40031.1 - 0.046 13.0 0.0 9.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ40031.1 - 0.096 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KEZ40031.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ40031.1 - 0.24 10.0 0.2 0.35 9.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein RGS PF00615.19 KEZ40032.1 - 0.0024 18.1 0.0 0.3 11.4 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain NAD_binding_10 PF13460.6 KEZ40033.1 - 5.9e-16 58.9 0.0 9.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ40033.1 - 7.1e-11 42.1 0.0 8.6e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family AMP-binding PF00501.28 KEZ40035.1 - 6e-227 753.2 0.0 2.2e-78 263.7 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KEZ40035.1 - 4.1e-179 596.0 0.0 9.7e-35 120.1 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 KEZ40035.1 - 1.1e-49 166.6 17.1 6.8e-09 36.0 0.4 7.2 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ40035.1 - 2e-08 35.1 0.0 0.03 15.3 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KEZ40035.1 - 3.5e-06 26.0 0.2 1 7.9 0.0 4.8 5 0 0 5 5 5 3 Transferase family WES_acyltransf PF03007.16 KEZ40035.1 - 0.00013 21.8 0.5 0.47 10.2 0.3 4.7 5 0 0 5 5 5 1 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.6 KEZ40036.1 - 7.5e-109 364.0 0.0 8.9e-109 363.7 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ40036.1 - 6.3e-08 32.2 0.0 8.8e-07 28.5 0.0 2.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ40036.1 - 1.8e-05 24.2 0.0 0.00022 20.6 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Collagen PF01391.18 KEZ40036.1 - 1.3 8.8 8.2 0.062 13.1 2.5 1.6 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) IF-2B PF01008.17 KEZ40037.1 - 7.7e-16 58.1 0.0 1.7e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KEZ40037.1 - 6.9e-09 35.8 0.2 1.3e-07 31.7 0.0 2.7 3 0 0 3 3 3 1 NUDIX domain FF PF01846.19 KEZ40038.1 - 6.2e-11 42.3 0.3 6.2e-11 42.3 0.3 2.8 3 0 0 3 3 3 1 FF domain WW PF00397.26 KEZ40038.1 - 2.7e-09 37.0 3.3 2.7e-09 37.0 3.3 2.7 2 0 0 2 2 2 1 WW domain Cytochrom_B561 PF03188.16 KEZ40038.1 - 0.03 14.5 2.2 0.051 13.7 2.2 1.3 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF5641 PF18701.1 KEZ40038.1 - 0.059 13.5 1.9 0.3 11.3 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5641) DUF2427 PF10348.9 KEZ40038.1 - 0.22 11.3 1.0 0.6 9.9 1.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) DUF2306 PF10067.9 KEZ40038.1 - 3.5 7.8 10.2 0.58 10.4 5.7 1.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Ank_2 PF12796.7 KEZ40039.1 - 6.8e-16 58.6 0.1 9.6e-08 32.5 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ40039.1 - 8e-10 38.1 1.8 0.17 12.5 0.0 5.1 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 KEZ40039.1 - 2.5e-08 34.0 0.6 0.017 15.5 0.0 3.7 1 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KEZ40039.1 - 4.2e-08 33.3 0.9 0.043 14.3 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KEZ40039.1 - 2.5e-07 31.1 0.1 0.014 16.0 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) NTPase_I-T PF01931.18 KEZ40039.1 - 8.8e-06 25.6 0.2 1.5e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF84 Ank_2 PF12796.7 KEZ40040.1 - 4.8e-38 129.6 0.0 1.7e-14 54.1 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ40040.1 - 2.2e-21 75.6 0.0 4.3e-08 33.3 0.0 5.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ40040.1 - 7.9e-18 64.6 0.0 0.00056 20.4 0.0 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ40040.1 - 3.5e-17 60.7 0.0 0.09 13.4 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 KEZ40040.1 - 3e-13 49.5 0.0 0.19 12.2 0.0 8.2 9 0 0 9 9 9 3 Ankyrin repeat NACHT PF05729.12 KEZ40040.1 - 3e-05 24.0 0.0 6.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ40040.1 - 9.1e-05 22.9 0.0 0.00049 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ40040.1 - 0.00028 21.2 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain PIF PF05092.12 KEZ40040.1 - 0.15 10.8 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 Per os infectivity Nop16 PF09420.10 KEZ40041.1 - 0.00054 20.1 1.4 0.00054 20.1 1.4 2.3 3 0 0 3 3 3 1 Ribosome biogenesis protein Nop16 DUF2514 PF10721.9 KEZ40041.1 - 0.065 13.3 15.6 0.52 10.3 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) AAA_23 PF13476.6 KEZ40041.1 - 0.25 11.8 17.5 0.047 14.2 3.8 2.4 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 KEZ40041.1 - 0.3 9.0 12.1 0.62 7.9 0.6 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Halogen_Hydrol PF10112.9 KEZ40041.1 - 0.59 10.1 12.2 0.18 11.8 1.0 3.3 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Sec8_exocyst PF04048.14 KEZ40041.1 - 1.1 9.1 11.1 0.49 10.3 1.0 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GAS PF13851.6 KEZ40041.1 - 2.5 7.4 29.2 1.3 8.3 12.2 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 KEZ40041.1 - 7.7 5.7 12.8 1 8.6 2.6 2.5 2 0 0 2 2 2 0 TMPIT-like protein PAP2 PF01569.21 KEZ40042.1 - 3.1e-27 95.0 2.0 3.1e-27 95.0 2.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KEZ40042.1 - 0.014 15.1 11.3 0.098 12.3 8.4 2.7 1 1 0 1 1 1 0 PAP2 superfamily Proteasome PF00227.26 KEZ40043.1 - 8.4e-61 204.8 0.1 1e-60 204.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEZ40043.1 - 2.8e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 KEZ40043.1 - 0.023 14.8 0.4 0.055 13.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 KEZ40043.1 - 0.047 13.2 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.13 KEZ40044.1 - 2.3e-24 86.0 0.0 3.7e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KEZ40044.1 - 2.2e-18 66.8 0.8 5.9e-18 65.4 0.8 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KEZ40044.1 - 2.3e-09 37.0 7.7 4.4e-09 36.1 7.7 1.5 1 0 0 1 1 1 1 PHD-finger Med7 PF05983.11 KEZ40045.1 - 7.5e-61 205.6 0.8 9.1e-61 205.3 0.8 1.1 1 0 0 1 1 1 1 MED7 protein Lsr2 PF11774.8 KEZ40046.1 - 0.014 15.5 1.5 0.015 15.4 1.5 1.1 1 0 0 1 1 1 0 Lsr2 DUF747 PF05346.11 KEZ40047.1 - 1.5e-93 313.8 0.3 2e-93 313.4 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family LAMTOR PF15454.6 KEZ40047.1 - 0.00039 21.0 0.2 0.0012 19.4 0.2 1.8 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Phage_Gp23 PF10669.9 KEZ40047.1 - 0.073 13.4 0.1 0.073 13.4 0.1 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) EBP PF05241.12 KEZ40048.1 - 2.3e-55 186.8 5.9 2.7e-55 186.6 5.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein TetR_C_33 PF13305.6 KEZ40048.1 - 0.073 13.8 0.3 0.15 12.8 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Spore_III_AE PF09546.10 KEZ40048.1 - 0.096 11.9 1.8 0.13 11.4 1.8 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) PS-DH PF14765.6 KEZ40049.1 - 8.9e-69 232.0 0.5 2.6e-68 230.5 0.2 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KEZ40049.1 - 1e-59 202.2 0.9 2.5e-58 197.7 0.0 2.8 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ40049.1 - 2e-56 190.8 0.0 1.1e-55 188.4 0.0 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KEZ40049.1 - 6.5e-56 190.2 0.1 1.2e-55 189.3 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEZ40049.1 - 3.4e-33 114.2 0.2 8.7e-33 112.8 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEZ40049.1 - 2.7e-24 85.8 0.0 1.1e-23 83.9 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KEZ40049.1 - 4.6e-20 72.2 0.0 1.3e-19 70.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KEZ40049.1 - 2e-17 64.5 0.0 9e-16 59.1 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ40049.1 - 1e-16 61.1 0.0 3.6e-16 59.3 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KEZ40049.1 - 1.2e-12 48.0 0.0 3.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40049.1 - 1.4e-10 41.7 0.0 7.6e-10 39.4 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40049.1 - 3.7e-09 37.1 0.0 1.4e-08 35.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40049.1 - 1.1e-07 31.8 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KEZ40049.1 - 6.8e-06 25.7 0.0 8.5e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KEZ40049.1 - 0.00016 21.9 0.0 0.00055 20.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KEZ40049.1 - 0.0011 18.6 0.0 0.003 17.2 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KEZ40049.1 - 0.0013 18.6 0.0 0.0037 17.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 KEZ40049.1 - 0.006 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 KEZ40049.1 - 0.0084 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 KEZ40049.1 - 0.025 15.6 0.0 0.14 13.1 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain SAT PF16073.5 KEZ40049.1 - 0.033 13.9 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_28 PF02636.17 KEZ40049.1 - 0.085 12.5 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KEZ40049.1 - 0.1 12.3 0.1 5.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Aminotran_1_2 PF00155.21 KEZ40050.1 - 6.9e-32 111.0 0.0 1e-31 110.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEZ40050.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KEZ40050.1 - 0.0019 16.8 0.0 0.0031 16.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KEZ40050.1 - 0.11 11.2 0.0 1.1 8.0 0.1 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain DLH PF01738.18 KEZ40051.1 - 1.4e-26 93.4 0.0 1.6e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 KEZ40051.1 - 0.041 13.2 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 KEZ40051.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family WD40 PF00400.32 KEZ40052.1 - 4.7e-40 134.8 14.3 4e-05 24.3 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 KEZ40052.1 - 5.7e-11 42.0 0.4 1.9e-10 40.4 0.3 2.0 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 KEZ40052.1 - 6.5e-11 42.0 0.3 1.5e-10 40.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KEZ40052.1 - 2.7e-07 30.8 0.3 2.5 8.5 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEZ40052.1 - 0.0039 16.8 1.2 0.06 12.9 0.8 2.5 2 1 0 2 2 2 1 PQQ-like domain F-box_4 PF15966.5 KEZ40052.1 - 0.019 14.9 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 F-box Nup160 PF11715.8 KEZ40052.1 - 0.11 11.2 4.3 60 2.1 0.0 4.7 2 2 2 6 6 6 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KEZ40052.1 - 0.16 12.5 0.4 43 4.8 0.1 3.7 3 0 0 3 3 3 0 PQQ-like domain Sorting_nexin PF03700.13 KEZ40053.1 - 0.0087 16.6 3.5 0.0087 16.6 3.5 2.1 2 0 0 2 2 2 1 Sorting nexin, N-terminal domain TraQ PF09679.10 KEZ40053.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) TPR_MLP1_2 PF07926.12 KEZ40054.1 - 1.2e-40 138.5 50.9 1.2e-39 135.3 30.4 18.9 8 4 9 17 17 17 4 TPR/MLP1/MLP2-like protein HOOK PF05622.12 KEZ40054.1 - 4.4e-05 21.9 15.0 4.4e-05 21.9 15.0 10.9 4 3 4 9 9 9 2 HOOK protein DUF5082 PF16888.5 KEZ40054.1 - 0.00036 20.8 8.5 0.00036 20.8 8.5 16.1 8 5 6 15 15 15 3 Domain of unknown function (DUF5082) DUF812 PF05667.11 KEZ40054.1 - 0.00037 19.5 25.8 0.00037 19.5 25.8 11.0 4 3 4 11 11 11 1 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 KEZ40054.1 - 0.0019 17.8 14.1 0.0019 17.8 14.1 15.2 5 3 9 16 16 16 2 Golgin subfamily A member 5 CALCOCO1 PF07888.11 KEZ40054.1 - 0.0021 17.0 28.8 0.0021 17.0 28.8 9.6 5 2 4 9 9 9 2 Calcium binding and coiled-coil domain (CALCOCO1) like LPP PF04728.13 KEZ40054.1 - 0.068 13.6 0.1 0.068 13.6 0.1 17.8 19 4 0 19 19 19 0 Lipoprotein leucine-zipper SKG6 PF08693.10 KEZ40055.1 - 0.015 14.7 0.7 0.028 13.8 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KEZ40055.1 - 0.032 14.2 2.2 0.098 12.6 2.2 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF2207 PF09972.9 KEZ40055.1 - 0.27 9.9 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_HK97_TLTM PF06120.11 KEZ40055.1 - 0.45 9.6 2.7 0.63 9.2 2.7 1.1 1 0 0 1 1 1 0 Tail length tape measure protein PIR PF00399.19 KEZ40056.1 - 0.00062 19.3 1.4 0.0016 18.0 1.4 1.8 1 0 0 1 1 1 1 Yeast PIR protein repeat Glyco_hydro_2_C PF02836.17 KEZ40057.1 - 4.8e-104 347.7 0.2 7.2e-104 347.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KEZ40057.1 - 7.4e-62 209.1 0.0 1.2e-61 208.5 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KEZ40057.1 - 8.3e-40 136.5 0.0 1.5e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KEZ40057.1 - 4.6e-21 75.1 0.0 5.8e-19 68.4 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KEZ40057.1 - 5.7e-12 46.3 0.0 1.3e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KEZ40057.1 - 0.005 17.4 0.0 0.017 15.7 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain CBP PF12192.8 KEZ40058.1 - 4.4e-05 23.6 5.4 8.2e-05 22.7 5.4 1.4 1 0 0 1 1 1 1 Fungal calcium binding protein PEP-utilisers_N PF05524.13 KEZ40058.1 - 0.047 13.9 0.1 0.85 9.8 0.0 2.3 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal TrmK PF04816.12 KEZ40059.1 - 0.039 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase DUF2456 PF10445.9 KEZ40061.1 - 2.6e-17 62.7 0.6 6.1e-17 61.5 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF2730 PF10805.8 KEZ40062.1 - 0.012 15.6 0.4 0.012 15.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CtIP_N PF10482.9 KEZ40062.1 - 0.13 12.3 12.1 0.19 11.7 2.4 2.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DivIC PF04977.15 KEZ40062.1 - 0.59 9.9 6.4 0.24 11.2 1.2 2.7 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 KEZ40062.1 - 0.65 10.3 6.1 2.2 8.6 1.0 3.6 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF3086 PF11285.8 KEZ40062.1 - 1.1 8.3 6.2 0.077 12.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DUF5082 PF16888.5 KEZ40062.1 - 1.8 8.9 6.1 9.1 6.6 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) betaPIX_CC PF16523.5 KEZ40062.1 - 3.9 7.4 8.0 8.5 6.3 0.3 2.5 2 0 0 2 2 2 0 betaPIX coiled coil YabA PF06156.13 KEZ40062.1 - 5.7 7.6 8.2 1.3 9.7 0.6 2.6 2 0 0 2 2 2 0 Initiation control protein YabA CDH-cyt PF16010.5 KEZ40063.1 - 5.9e-62 208.6 2.2 8.6e-62 208.1 1.4 1.7 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KEZ40063.1 - 1.5e-26 93.4 0.0 3.5e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ40063.1 - 2.8e-24 86.3 0.3 5e-24 85.5 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 KEZ40063.1 - 3.5e-10 39.7 8.6 1.2e-09 37.9 8.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 KEZ40063.1 - 1.4e-08 34.2 0.0 0.00012 21.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEZ40063.1 - 1.2e-05 25.4 0.0 3.8e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ40063.1 - 0.00013 21.6 0.3 0.0011 18.6 0.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ40063.1 - 0.00024 20.4 0.0 0.00042 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40063.1 - 0.0016 17.3 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KEZ40063.1 - 0.0026 16.9 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ40063.1 - 0.0042 16.4 0.1 0.03 13.6 0.2 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 KEZ40063.1 - 0.014 15.9 0.0 0.16 12.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ40063.1 - 0.019 14.3 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KEZ40063.1 - 0.024 14.0 0.0 0.073 12.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ40063.1 - 0.033 13.4 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 KEZ40064.1 - 3.4e-41 140.9 0.1 9.6e-41 139.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40064.1 - 2.1e-26 92.4 0.1 9.8e-26 90.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ40064.1 - 0.00011 22.3 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KEZ40064.1 - 0.00018 20.4 0.0 0.0004 19.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain UTP25 PF06862.12 KEZ40064.1 - 0.011 14.5 0.0 3.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 KEZ40064.1 - 0.11 12.7 0.3 0.47 10.7 0.3 2.1 1 1 0 1 1 1 0 AAA domain Hira PF07569.11 KEZ40065.1 - 3.5e-84 282.0 0.0 1.2e-83 280.2 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 KEZ40065.1 - 3.4e-30 103.6 20.1 3e-05 24.7 0.1 8.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ40065.1 - 1.4e-12 47.7 0.1 0.13 12.6 0.0 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KEZ40065.1 - 2.1e-10 40.2 0.5 4.9e-10 39.0 0.5 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KEZ40065.1 - 5.7e-06 26.1 1.3 15 5.7 0.0 5.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KEZ40065.1 - 0.0031 16.5 0.7 0.25 10.2 0.0 3.6 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEZ40065.1 - 0.011 15.6 0.1 1.3 8.9 0.0 3.5 4 1 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KEZ40065.1 - 0.02 12.9 0.1 0.092 10.7 0.0 1.9 2 0 0 2 2 2 0 IKI3 family DUF3682 PF12446.8 KEZ40065.1 - 0.07 13.6 11.1 0.22 12.0 11.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Atrophin-1 PF03154.15 KEZ40065.1 - 0.3 9.3 4.3 0.15 10.3 1.4 1.9 2 0 0 2 2 2 0 Atrophin-1 family RNA_pol_Rpc4 PF05132.14 KEZ40065.1 - 1.5 9.2 6.9 2.9 8.3 6.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PBP_sp32 PF07222.12 KEZ40065.1 - 6.8 6.1 8.7 12 5.3 8.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Glyco_transf_15 PF01793.16 KEZ40066.1 - 1.1e-16 61.0 3.3 1.1e-14 54.5 2.2 2.9 2 1 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase CBP_BcsQ PF06564.12 KEZ40066.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Nuc_sug_transp PF04142.15 KEZ40067.1 - 3.9e-93 312.1 3.9 5.3e-93 311.6 3.9 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KEZ40067.1 - 1.4e-06 27.7 7.4 8.9e-06 25.1 7.3 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEZ40067.1 - 8e-06 26.1 29.1 0.0057 16.8 8.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 KEZ40067.1 - 0.00011 21.7 9.7 0.066 12.6 4.0 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF543 PF04418.12 KEZ40067.1 - 0.028 14.4 3.1 1.3 9.1 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF543) HPP PF04982.13 KEZ40067.1 - 2.3 8.4 7.8 38 4.5 0.7 3.9 3 1 0 3 3 3 0 HPP family TMEM234 PF10639.9 KEZ40067.1 - 8.5 6.5 7.8 1.2 9.1 0.4 2.6 3 0 0 3 3 3 0 Putative transmembrane family 234 NTP_transferase PF00483.23 KEZ40068.1 - 2.8e-31 109.0 0.0 3.9e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KEZ40068.1 - 6.6e-13 47.8 5.7 6.2e-07 28.9 0.0 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KEZ40068.1 - 1.7e-07 31.8 0.0 2.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KEZ40068.1 - 0.042 12.0 0.0 0.11 10.6 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KEZ40068.1 - 0.22 11.3 1.0 6.3 6.6 0.0 3.3 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Dynamin_M PF01031.20 KEZ40069.1 - 1e-20 74.1 0.1 6.9e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KEZ40069.1 - 1.3e-19 70.9 0.0 1.4e-18 67.5 0.0 2.5 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KEZ40069.1 - 1.6e-06 28.2 0.4 0.00028 21.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KEZ40069.1 - 0.00046 20.2 0.7 0.039 14.0 0.1 3.4 2 2 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KEZ40069.1 - 0.052 14.1 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 KEZ40069.1 - 0.22 11.7 0.5 1.6 8.9 0.0 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Sugar_tr PF00083.24 KEZ40070.1 - 4.2e-82 276.4 19.2 5e-82 276.2 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40070.1 - 2.1e-27 96.0 16.2 2.8e-27 95.6 16.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ40070.1 - 2.8e-05 22.7 2.2 2.8e-05 22.7 2.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KEZ40070.1 - 0.00016 20.3 2.7 0.00016 20.3 2.7 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Sortilin-Vps10 PF15902.5 KEZ40071.1 - 3e-17 62.6 0.5 0.00013 20.9 0.0 5.6 4 2 1 6 6 6 4 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 KEZ40071.1 - 2.9e-14 52.7 10.8 9.9e-14 51.0 10.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 KEZ40071.1 - 1.1e-09 36.8 22.3 0.79 10.0 0.1 9.2 9 0 0 9 9 9 4 BNR/Asp-box repeat Kelch_6 PF13964.6 KEZ40071.1 - 0.0079 16.5 0.4 31 5.1 0.0 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 KEZ40071.1 - 0.014 15.4 0.1 7.8 6.6 0.0 3.3 2 0 0 2 2 2 0 Galactose oxidase, central domain BNR_6 PF15899.5 KEZ40071.1 - 1.5 9.1 5.8 19 5.7 0.0 5.4 7 0 0 7 7 7 0 BNR-Asp box repeat Gpi16 PF04113.14 KEZ40072.1 - 1e-244 813.2 0.0 1.2e-244 813.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 KEZ40073.1 - 6.6e-71 238.9 1.8 8.1e-71 238.6 1.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF1241 PF06840.11 KEZ40073.1 - 0.0028 17.3 0.2 0.0054 16.4 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1241) T4SS PF07996.11 KEZ40073.1 - 0.012 16.0 1.3 0.013 15.9 0.4 1.5 2 0 0 2 2 2 0 Type IV secretion system proteins GIT1_C PF12205.8 KEZ40073.1 - 0.017 15.2 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DASH_Duo1 PF08651.10 KEZ40073.1 - 0.057 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF2130 PF09903.9 KEZ40073.1 - 0.072 12.4 1.5 0.13 11.5 1.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF3418 PF11898.8 KEZ40073.1 - 0.095 11.4 0.8 0.12 11.0 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3418) PIN_8 PF18476.1 KEZ40073.1 - 0.12 12.3 0.9 0.18 11.7 0.5 1.4 1 1 0 1 1 1 0 PIN like domain Spc7 PF08317.11 KEZ40073.1 - 0.18 10.6 2.5 0.11 11.3 0.6 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Tli4_N PF18443.1 KEZ40073.1 - 0.22 11.9 2.1 1.3 9.3 0.1 2.1 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain Glyco_hydro_3 PF00933.21 KEZ40074.1 - 4.5e-61 207.0 0.0 6e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEZ40074.1 - 0.0018 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 KEZ40074.1 - 0.0079 16.4 0.0 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 KEZ40074.1 - 0.017 15.3 0.0 0.057 13.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fe_hyd_SSU PF02256.17 KEZ40074.1 - 0.052 13.6 0.1 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit Amidohydro_1 PF01979.20 KEZ40075.1 - 1.1e-15 57.8 0.0 1.6e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ40075.1 - 7.2e-12 45.5 0.1 3.6e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family NDT80_PhoG PF05224.12 KEZ40076.1 - 3.6e-32 112.1 0.0 8.3e-32 110.9 0.0 1.6 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.20 KEZ40077.1 - 4.3e-20 72.6 0.0 6.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 KEZ40078.1 - 5.1e-52 176.7 0.0 7e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEZ40078.1 - 5.3e-39 134.2 0.0 7.6e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase p450 PF00067.22 KEZ40079.1 - 6.4e-61 206.5 0.0 9.3e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Filament PF00038.21 KEZ40080.1 - 0.00027 20.6 149.5 0.04 13.5 18.5 7.0 1 1 4 6 6 6 5 Intermediate filament protein HOOK PF05622.12 KEZ40080.1 - 0.00038 18.8 48.6 0.00038 18.8 48.6 3.6 1 1 2 3 3 3 1 HOOK protein DUF3584 PF12128.8 KEZ40080.1 - 0.00071 17.2 47.3 0.00071 17.2 47.3 4.2 1 1 3 4 4 4 2 Protein of unknown function (DUF3584) HrpB7 PF09486.10 KEZ40080.1 - 0.01 16.2 24.8 0.01 16.2 24.8 10.1 1 1 11 12 12 12 0 Bacterial type III secretion protein (HrpB7) HSBP1 PF06825.12 KEZ40080.1 - 0.039 13.8 2.7 1.3 8.9 1.0 4.3 4 0 0 4 4 4 0 Heat shock factor binding protein 1 Spc7 PF08317.11 KEZ40080.1 - 0.65 8.8 173.9 0.69 8.7 29.6 8.5 1 1 7 8 8 8 0 Spc7 kinetochore protein Myc-LZ PF02344.15 KEZ40080.1 - 9 6.5 14.3 0.27 11.4 2.6 4.3 3 0 0 3 3 3 0 Myc leucine zipper domain Mannosyl_trans2 PF04188.13 KEZ40081.1 - 6.3e-52 177.4 6.7 1.4e-51 176.3 6.7 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT_2 PF13231.6 KEZ40081.1 - 1.5e-05 25.2 17.4 4.1e-05 23.8 7.4 2.8 2 1 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Myco_arth_vir_N PF09610.10 KEZ40081.1 - 3.5 7.8 5.4 2.3 8.4 0.8 3.0 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) PTPA PF03095.15 KEZ40082.1 - 2.2e-117 391.8 0.0 2.5e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NPC1_N PF16414.5 KEZ40084.1 - 3.2e-74 249.5 7.3 4.9e-74 249.0 7.3 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KEZ40084.1 - 4.5e-73 246.7 19.6 5.4e-72 243.1 19.6 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KEZ40084.1 - 5e-52 175.8 6.4 5e-52 175.8 6.4 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KEZ40084.1 - 8.1e-07 28.3 31.9 0.00012 21.1 10.5 2.6 3 0 0 3 3 3 2 MMPL family Folate_rec PF03024.14 KEZ40084.1 - 3.5e-05 23.8 1.5 7.5e-05 22.7 1.5 1.5 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 KEZ40084.1 - 0.4 8.3 20.0 0.034 11.8 12.1 2.2 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Amidase PF01425.21 KEZ40085.1 - 7.6e-73 246.0 0.0 5.6e-72 243.1 0.0 1.9 1 1 0 1 1 1 1 Amidase TauD PF02668.16 KEZ40086.1 - 1e-52 179.6 0.9 1.2e-52 179.4 0.9 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pribosyltran PF00156.27 KEZ40087.1 - 2.6e-06 27.1 0.1 5.8e-06 25.9 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.6 KEZ40088.1 - 2.3e-41 140.4 0.0 5.8e-41 139.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KEZ40088.1 - 2.9e-38 131.7 1.3 4.5e-32 111.6 0.6 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KEZ40088.1 - 4.6e-17 62.0 0.9 9.1e-17 61.0 0.9 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4392 PF14336.6 KEZ40088.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4392) UPRTase PF14681.6 KEZ40088.1 - 0.085 12.3 0.3 0.17 11.3 0.2 1.6 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase DPM3 PF08285.11 KEZ40091.1 - 4.7e-37 126.1 0.1 5.2e-37 125.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Zn_clus PF00172.18 KEZ40092.1 - 4.7e-08 33.0 6.3 4.7e-08 33.0 6.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG9 PF04109.16 KEZ40092.1 - 0.14 11.2 0.3 0.18 10.8 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 AAA PF00004.29 KEZ40093.1 - 5.5e-16 59.2 0.0 1.2e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ40093.1 - 0.0013 19.1 0.7 0.011 16.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ40093.1 - 0.0013 19.1 0.1 0.0034 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KEZ40093.1 - 0.02 14.6 0.4 0.077 12.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KEZ40093.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MRVI1 PF05781.12 KEZ40093.1 - 0.036 12.8 0.2 0.13 10.9 0.1 1.9 2 0 0 2 2 2 0 MRVI1 protein AAA_19 PF13245.6 KEZ40093.1 - 0.08 13.3 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KEZ40093.1 - 0.084 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.6 KEZ40093.1 - 0.36 10.6 2.6 0.9 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DehI PF10778.9 KEZ40094.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI p450 PF00067.22 KEZ40095.1 - 6e-63 213.2 0.0 7.6e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LRR_8 PF13855.6 KEZ40096.1 - 1.6e-34 117.5 29.2 2.4e-08 33.6 0.9 6.9 6 1 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 KEZ40096.1 - 6.8e-27 93.1 29.2 2e-05 24.9 0.1 8.7 6 3 5 11 11 11 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KEZ40096.1 - 5.8e-07 29.1 21.9 1.5 9.1 0.1 9.3 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 KEZ40096.1 - 7.1e-06 25.9 22.4 6.7 7.7 0.2 10.8 12 2 0 12 12 12 3 Leucine Rich Repeat LRR_9 PF14580.6 KEZ40096.1 - 3.7e-05 23.3 13.4 0.064 12.8 0.0 5.3 2 2 4 6 6 6 3 Leucine-rich repeat zf-CCCH PF00642.24 KEZ40097.1 - 1.4e-08 34.4 3.4 2.9e-08 33.4 3.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KEZ40097.1 - 8.3e-08 32.0 5.1 1.5e-07 31.2 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ40097.1 - 2.7e-07 30.3 7.7 4.5e-07 29.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ40097.1 - 4.6e-07 29.8 6.6 8.5e-07 28.9 6.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEZ40097.1 - 2.1e-06 27.5 9.0 3.7e-06 26.7 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ40097.1 - 3.4e-06 26.9 8.3 5.8e-06 26.2 8.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 KEZ40097.1 - 1.3e-05 25.3 3.1 1.3e-05 25.3 3.1 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 KEZ40097.1 - 1.5e-05 25.2 7.0 2.8e-05 24.4 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 KEZ40097.1 - 1.6e-05 24.8 6.2 3.4e-05 23.7 6.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEZ40097.1 - 0.00047 19.9 2.9 0.00047 19.9 2.9 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KEZ40097.1 - 0.0075 16.1 6.1 0.013 15.3 6.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEZ40097.1 - 0.011 15.9 8.8 0.023 14.9 8.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KEZ40097.1 - 0.1 12.9 3.8 0.21 11.9 3.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 KEZ40097.1 - 0.1 12.4 0.9 0.18 11.6 0.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Herpes_DNAp_acc PF04929.12 KEZ40097.1 - 2.9 6.8 7.8 4.3 6.2 7.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor zf-CCCH_2 PF14608.6 KEZ40097.1 - 3.1 8.4 8.3 0.81 10.3 4.8 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Sec15 PF04091.12 KEZ40098.1 - 2.1e-82 277.1 4.9 2.1e-82 277.1 4.9 2.7 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like FAD_binding_4 PF01565.23 KEZ40098.1 - 4.2e-28 97.8 0.0 7.4e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SKA2 PF16740.5 KEZ40098.1 - 0.062 13.1 0.9 0.29 10.9 0.9 2.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF5344 PF17279.2 KEZ40098.1 - 1.1 9.9 12.5 3.5 8.3 2.3 5.0 5 0 0 5 5 5 0 Family of unknown function (DUF5344) DUF4201 PF13870.6 KEZ40098.1 - 1.8 8.3 13.4 1.2 8.9 6.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) COG5 PF10392.9 KEZ40098.1 - 6.2 7.0 9.7 1.4 9.1 2.6 3.3 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TrkH PF02386.16 KEZ40099.1 - 7.5e-122 407.3 5.4 6.9e-119 397.5 5.3 2.0 2 0 0 2 2 2 2 Cation transport protein NmrA PF05368.13 KEZ40100.1 - 2.4e-13 50.2 0.2 5.4e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family Semialdhyde_dh PF01118.24 KEZ40100.1 - 0.003 18.0 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KEZ40100.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding DUF4448 PF14610.6 KEZ40101.1 - 2.4e-29 102.4 0.0 3.4e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) FTSW_RODA_SPOVE PF01098.19 KEZ40101.1 - 0.039 12.9 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Cell cycle protein SKG6 PF08693.10 KEZ40101.1 - 5.5 6.5 9.7 0.16 11.4 3.2 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain SGL PF08450.12 KEZ40102.1 - 6.1e-05 22.7 0.0 0.017 14.7 0.0 2.8 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region GSDH PF07995.11 KEZ40102.1 - 0.036 13.4 0.9 0.16 11.2 0.7 2.4 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase NHL PF01436.21 KEZ40102.1 - 0.056 13.5 0.0 1.5 9.0 0.0 3.3 2 1 1 3 3 3 0 NHL repeat Reg_prop PF07494.11 KEZ40102.1 - 0.088 13.1 0.0 0.94 9.9 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller AMP-binding PF00501.28 KEZ40103.1 - 1.2e-66 225.0 0.0 1.7e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KEZ40103.1 - 1.9e-63 214.0 0.0 2.9e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KEZ40103.1 - 7.6e-09 35.4 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KEZ40103.1 - 5.4e-08 33.1 0.0 1.3e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KEZ40103.1 - 1.1e-05 25.4 0.1 0.00012 22.0 0.1 2.7 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ40103.1 - 0.00087 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KEZ40103.1 - 0.0012 19.8 0.0 0.0058 17.6 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KEZ40103.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HEAT_2 PF13646.6 KEZ40104.1 - 2.2e-06 28.0 6.8 0.042 14.2 0.0 4.2 3 1 1 4 4 4 2 HEAT repeats Arm PF00514.23 KEZ40104.1 - 4.4e-05 23.4 5.6 0.0048 16.9 0.5 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEZ40104.1 - 0.0012 19.3 0.9 0.32 11.5 0.2 4.4 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.22 KEZ40104.1 - 0.0056 16.8 0.3 0.04 14.2 0.1 2.7 2 0 0 2 2 2 1 HEAT repeat KAP PF05804.12 KEZ40104.1 - 0.053 11.7 0.0 0.37 8.9 0.0 1.9 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) Arm_2 PF04826.13 KEZ40104.1 - 0.096 12.1 0.7 4.8 6.6 0.1 2.5 3 0 0 3 3 3 0 Armadillo-like Mur_ligase_C PF02875.21 KEZ40104.1 - 0.11 12.8 0.0 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Adaptin_N PF01602.20 KEZ40104.1 - 0.22 10.0 0.7 1.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Ribosomal_L13e PF01294.18 KEZ40105.1 - 7.4e-70 234.4 0.8 9.1e-70 234.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e COX14 PF14880.6 KEZ40106.1 - 7.3e-17 61.0 0.4 1.2e-16 60.3 0.4 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Myb_DNA-bind_4 PF13837.6 KEZ40106.1 - 0.0049 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF3168 PF11367.8 KEZ40106.1 - 0.0052 17.0 0.6 0.011 16.0 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3168) CD52 PF15116.6 KEZ40106.1 - 2.1 8.5 3.8 4.5 7.4 3.8 1.5 1 0 0 1 1 1 0 CAMPATH-1 antigen DAHP_synth_1 PF00793.20 KEZ40108.1 - 1.1e-105 352.4 0.2 1.4e-105 352.2 0.2 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AbiEi_1 PF09407.10 KEZ40108.1 - 0.0098 16.2 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 AbiEi antitoxin C-terminal domain Ribosomal_L50 PF10501.9 KEZ40110.1 - 2.4e-12 47.0 0.1 1.5e-11 44.4 0.1 2.2 1 1 0 1 1 1 1 Ribosomal subunit 39S CENP-Q PF13094.6 KEZ40110.1 - 0.016 15.4 1.1 0.016 15.4 1.1 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2396 PF09654.10 KEZ40110.1 - 0.064 13.4 0.1 0.41 10.7 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2396) CVNH PF08881.10 KEZ40111.1 - 2.4e-26 92.3 0.1 2.7e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 CVNH domain ABC2_membrane PF01061.24 KEZ40112.1 - 4e-95 317.2 56.1 2.9e-50 170.6 19.8 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KEZ40112.1 - 7.4e-36 121.9 11.7 8.6e-32 108.9 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 KEZ40112.1 - 4.1e-35 121.3 0.0 1.5e-16 61.1 0.0 3.2 3 1 1 4 4 4 2 ABC transporter ABC_trans_N PF14510.6 KEZ40112.1 - 3e-16 59.8 0.1 6.7e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEZ40112.1 - 6e-07 30.0 0.6 0.0009 19.7 0.1 2.7 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ40112.1 - 2.4e-06 27.6 0.1 0.00079 19.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KEZ40112.1 - 7.4e-06 25.7 0.1 0.00029 20.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ40112.1 - 6.6e-05 22.6 0.6 0.031 14.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KEZ40112.1 - 7.9e-05 23.2 0.0 0.024 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEZ40112.1 - 0.00015 21.7 0.0 1 9.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KEZ40112.1 - 0.0013 18.9 0.1 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ40112.1 - 0.0019 18.4 0.4 0.86 9.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KEZ40112.1 - 0.0046 17.4 0.0 3.5 8.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 KEZ40112.1 - 0.017 14.6 0.0 5.1 6.5 0.0 3.7 3 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 KEZ40112.1 - 0.019 14.1 45.6 0.005 16.0 11.2 3.9 3 2 0 3 3 3 0 ABC-2 family transporter protein NACHT PF05729.12 KEZ40112.1 - 0.024 14.6 0.3 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KEZ40112.1 - 0.028 14.0 1.2 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KEZ40112.1 - 0.041 13.6 0.1 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEZ40112.1 - 0.063 13.0 0.0 12 5.6 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 KEZ40112.1 - 0.095 12.4 0.3 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEZ40112.1 - 0.11 13.0 0.6 0.22 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 KEZ40112.1 - 0.14 12.6 0.0 31 5.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Transgly_assoc PF04226.13 KEZ40112.1 - 0.28 11.5 3.6 3.3 8.0 0.1 3.0 3 0 0 3 3 2 0 Transglycosylase associated protein Vint PF14623.6 KEZ40113.1 - 6.4e-58 195.2 0.0 1.6e-57 193.9 0.0 1.7 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 KEZ40113.1 - 6.9e-21 74.2 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KEZ40113.1 - 3.4e-13 50.2 0.0 9e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEZ40113.1 - 1.7e-10 41.4 0.0 4.7e-10 40.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KEZ40113.1 - 3.7e-08 33.4 0.0 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Hint PF01079.20 KEZ40113.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Hint module RCC1 PF00415.18 KEZ40114.1 - 2e-61 204.4 0.4 1.6e-09 38.2 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEZ40114.1 - 5.8e-43 143.9 22.2 1.5e-08 34.2 0.3 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 KEZ40114.1 - 0.0023 17.8 0.0 6.8 6.6 0.0 3.6 3 1 0 3 3 3 2 Peptidase family C25, C terminal ig-like domain Sec34 PF04136.15 KEZ40116.1 - 1.6e-44 151.4 4.3 4.2e-44 150.0 4.3 1.8 1 0 0 1 1 1 1 Sec34-like family CdiI_2 PF18593.1 KEZ40116.1 - 0.07 13.8 0.5 0.47 11.1 0.1 2.6 2 0 0 2 2 2 0 CdiI immunity protein SKA2 PF16740.5 KEZ40116.1 - 0.17 11.7 0.8 7.5 6.4 0.1 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 NAD_binding_10 PF13460.6 KEZ40117.1 - 6e-08 32.8 0.0 2.9e-07 30.6 0.0 2.1 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KEZ40117.1 - 2.1e-05 24.1 0.0 0.00025 20.6 0.0 2.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ40117.1 - 2.7e-05 23.8 0.0 0.0099 15.4 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family 2-Hacid_dh_C PF02826.19 KEZ40117.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 KEZ40117.1 - 0.028 14.3 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.17 KEZ40117.1 - 0.087 13.4 0.1 0.63 10.7 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KEZ40117.1 - 0.21 11.2 0.0 0.53 9.9 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.28 KEZ40119.1 - 1.5e-94 317.0 0.0 1.8e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ40119.1 - 1.8e-13 51.3 0.0 4.2e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2575 PF10837.8 KEZ40119.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) ECH_1 PF00378.20 KEZ40120.1 - 1.4e-55 188.4 0.0 1.8e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ40120.1 - 4.3e-23 82.3 0.0 1e-22 81.1 0.0 1.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 KEZ40121.1 - 5.3e-100 335.4 0.0 7.8e-97 325.0 0.0 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain CN_hydrolase PF00795.22 KEZ40122.1 - 1.7e-42 145.6 0.0 2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L30_N PF08079.12 KEZ40122.1 - 0.34 11.2 0.7 35 4.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Fungal_trans PF04082.18 KEZ40123.1 - 7.5e-28 97.3 0.0 1.4e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ40123.1 - 1.1e-22 80.5 41.0 1.1e-22 80.5 41.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3593 PF12159.8 KEZ40123.1 - 0.031 14.3 1.9 0.32 11.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Sugar_tr PF00083.24 KEZ40124.1 - 1.8e-86 290.8 21.5 2.2e-86 290.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40124.1 - 1.1e-25 90.3 40.2 1.9e-18 66.5 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Imm58 PF15581.6 KEZ40124.1 - 0.2 11.7 0.6 0.82 9.8 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 58 Fungal_trans PF04082.18 KEZ40125.1 - 0.005 15.9 0.1 0.45 9.5 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain p450 PF00067.22 KEZ40126.1 - 1.5e-40 139.3 0.0 1.9e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEZ40127.1 - 8.9e-32 110.4 28.9 9.2e-31 107.0 28.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Gly_transf_sug PF04488.15 KEZ40127.1 - 2.6e-10 40.8 0.0 5.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NAD_binding_10 PF13460.6 KEZ40128.1 - 1.1e-09 38.5 0.0 3.6e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ40128.1 - 1e-08 35.0 0.0 6.6e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEZ40128.1 - 1.6e-08 34.3 0.1 0.00062 19.3 0.1 3.9 2 2 1 3 3 3 3 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ40128.1 - 0.058 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 KR domain PHO4 PF01384.20 KEZ40129.1 - 1.2e-101 340.1 13.7 1.4e-101 339.9 13.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KEZ40129.1 - 0.42 10.9 6.9 2.4 8.5 0.3 2.7 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 CMAS PF02353.20 KEZ40130.1 - 2.3e-61 207.5 0.1 2.9e-61 207.2 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KEZ40130.1 - 4.1e-09 36.5 0.0 6.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40130.1 - 1.6e-07 31.9 0.0 2.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40130.1 - 1e-06 29.4 0.0 2.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KEZ40130.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 KEZ40130.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KEZ40130.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 KEZ40130.1 - 0.019 15.7 0.0 0.035 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KEZ40130.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 KEZ40130.1 - 0.081 12.6 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 DNA methylase adh_short PF00106.25 KEZ40131.1 - 2.4e-14 53.2 0.0 5.2e-14 52.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ40131.1 - 2.8e-07 30.4 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF669 PF05037.13 KEZ40131.1 - 0.053 13.6 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF669) FAD_binding_4 PF01565.23 KEZ40133.1 - 1.2e-21 76.9 0.0 2.6e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ40133.1 - 8.2e-11 41.8 0.1 1.5e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1700 PF08006.11 KEZ40134.1 - 0.48 9.9 3.6 0.71 9.4 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF2070 PF09843.9 KEZ40134.1 - 4.4 5.5 7.9 5.9 5.1 7.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VIT1 PF01988.19 KEZ40134.1 - 6.6 6.5 9.0 41 3.9 9.0 1.9 1 1 0 1 1 1 0 VIT family ABC_tran PF00005.27 KEZ40135.1 - 1.1e-37 129.6 0.0 2.8e-18 66.8 0.0 2.9 2 1 1 3 3 3 2 ABC transporter ABC_membrane PF00664.23 KEZ40135.1 - 2.7e-28 99.4 29.4 1.5e-22 80.6 12.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KEZ40135.1 - 7.7e-08 32.0 0.1 0.056 12.9 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ40135.1 - 2.4e-06 27.6 0.2 0.068 13.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ40135.1 - 0.00027 20.6 0.0 0.00064 19.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KEZ40135.1 - 0.0028 17.9 0.2 6.1 7.2 0.1 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 KEZ40135.1 - 0.0043 17.1 0.1 0.0098 16.0 0.1 1.6 1 0 0 1 1 1 1 Dynamin family IstB_IS21 PF01695.17 KEZ40135.1 - 0.011 15.4 0.5 1.1 8.9 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 KEZ40135.1 - 0.019 15.5 0.1 0.038 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ40135.1 - 0.024 14.2 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ40135.1 - 0.093 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ40135.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 KEZ40135.1 - 0.14 11.8 0.8 0.76 9.4 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Beta-lactamase PF00144.24 KEZ40137.1 - 1.3e-46 159.4 0.2 1.6e-46 159.1 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KEZ40137.1 - 0.0073 15.9 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase enzyme family VbhA PF18495.1 KEZ40137.1 - 0.026 14.4 0.1 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 Antitoxin VbhA Cyclase PF04199.13 KEZ40138.1 - 9.1e-16 58.3 0.1 1.3e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 KEZ40139.1 - 1.7e-80 271.1 15.4 2.1e-80 270.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40139.1 - 6.9e-28 97.6 13.4 1e-27 97.0 13.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ40139.1 - 6.8e-06 24.8 0.4 6.8e-06 24.8 0.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KEZ40139.1 - 2.1e-05 23.3 10.2 0.0016 17.1 2.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Pkinase PF00069.25 KEZ40140.1 - 1.6e-12 47.4 0.0 4.5e-06 26.2 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain APH PF01636.23 KEZ40140.1 - 0.021 14.7 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KEZ40140.1 - 0.028 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KEZ40140.1 - 0.048 12.9 0.0 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase Glyco_hydro_114 PF03537.13 KEZ40141.1 - 1.7e-49 168.2 0.3 2e-49 168.0 0.3 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ABC2_membrane PF01061.24 KEZ40142.1 - 1.5e-26 93.2 27.7 2.2e-26 92.6 27.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KEZ40142.1 - 3.8e-25 89.0 0.1 6.8e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ40142.1 - 8.2e-06 25.4 0.1 2.6e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ40142.1 - 1.9e-05 24.6 0.0 0.092 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ40142.1 - 2.9e-05 24.5 0.2 7.1e-05 23.2 0.1 1.7 2 0 0 2 2 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ40142.1 - 0.00024 21.0 0.1 0.0006 19.7 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KEZ40142.1 - 0.00043 19.9 0.3 0.00079 19.0 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KEZ40142.1 - 0.00072 19.3 0.3 0.0015 18.2 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ40142.1 - 0.00085 19.6 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ40142.1 - 0.0023 17.7 0.3 0.0038 17.0 0.3 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEZ40142.1 - 0.0026 16.9 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 KEZ40142.1 - 0.0032 17.2 0.1 0.011 15.4 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 KEZ40142.1 - 0.006 16.8 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KEZ40142.1 - 0.0077 16.8 0.2 0.015 15.8 0.2 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ40142.1 - 0.01 15.8 0.3 0.024 14.5 0.1 1.7 2 0 0 2 2 1 0 NACHT domain RuvB_N PF05496.12 KEZ40142.1 - 0.01 15.6 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 KEZ40142.1 - 0.011 15.9 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KEZ40142.1 - 0.017 15.6 0.2 0.066 13.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEZ40142.1 - 0.019 14.9 0.2 0.045 13.7 0.1 1.7 2 0 0 2 2 1 0 NTPase AAA_17 PF13207.6 KEZ40142.1 - 0.036 14.5 0.1 0.073 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEZ40142.1 - 0.041 13.5 0.2 0.066 12.8 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KEZ40142.1 - 0.048 14.1 0.1 0.32 11.4 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 KEZ40142.1 - 0.053 13.4 0.1 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 KEZ40142.1 - 0.075 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KEZ40142.1 - 0.081 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ40142.1 - 0.087 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEZ40142.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 KEZ40142.1 - 0.15 11.2 0.7 0.88 8.7 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 KEZ40142.1 - 0.16 11.6 0.6 0.31 10.6 0.2 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KEZ40142.1 - 0.17 11.9 0.1 0.82 9.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 KEZ40142.1 - 0.19 11.5 0.3 0.33 10.6 0.3 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_13 PF13166.6 KEZ40142.1 - 0.31 9.6 0.4 1.9 7.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 KEZ40142.1 - 4.5 6.3 34.9 0.7 8.9 23.0 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein PT-TG PF14449.6 KEZ40144.1 - 1.7e-07 31.0 0.3 6.4e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 Pre-toxin TG Peptidase_M13_N PF05649.13 KEZ40145.1 - 1.4e-97 327.8 0.0 1.9e-97 327.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KEZ40145.1 - 6.8e-63 212.0 0.5 2.1e-62 210.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M13 MFS_1 PF07690.16 KEZ40146.1 - 2.3e-30 105.7 56.5 4.6e-25 88.3 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KEZ40147.1 - 1.1e-39 136.0 0.0 1.5e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ40147.1 - 4.9e-30 104.8 0.1 6.3e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ40147.1 - 1.9e-08 34.4 0.1 5.7e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEZ40147.1 - 0.00044 19.8 0.1 0.0011 18.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEZ40147.1 - 0.00045 20.2 0.1 0.00084 19.3 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KEZ40147.1 - 0.00055 19.1 0.0 0.0009 18.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 KEZ40147.1 - 0.0055 16.1 0.0 0.032 13.6 0.0 1.9 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) CoA_binding_2 PF13380.6 KEZ40147.1 - 0.025 15.1 0.0 6.9 7.2 0.0 2.4 1 1 1 2 2 2 0 CoA binding domain NmrA PF05368.13 KEZ40147.1 - 0.12 12.0 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Fungal_trans PF04082.18 KEZ40148.1 - 5.7e-19 68.2 0.1 8.5e-19 67.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40148.1 - 2.2e-10 40.5 9.2 4.3e-10 39.6 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 KEZ40149.1 - 0.00034 21.3 0.9 0.00078 20.1 0.2 1.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family Beta-lactamase PF00144.24 KEZ40150.1 - 1e-41 143.3 0.8 4.6e-41 141.1 0.3 1.9 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 KEZ40150.1 - 1.3e-10 41.6 0.0 2.7e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Arf PF00025.21 KEZ40151.1 - 5.6e-27 94.3 0.0 9.5e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEZ40151.1 - 1.7e-06 28.2 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KEZ40151.1 - 4e-06 26.4 0.0 6.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KEZ40151.1 - 3.2e-05 23.3 0.6 0.33 10.1 0.1 3.0 1 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.22 KEZ40151.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KEZ40151.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 KEZ40151.1 - 0.057 13.0 0.1 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KEZ40151.1 - 0.075 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NAD_binding_10 PF13460.6 KEZ40152.1 - 2.4e-07 30.9 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ40152.1 - 1.4e-05 24.7 0.0 3.2e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family TrkH PF02386.16 KEZ40153.1 - 4.9e-126 421.1 0.6 1.8e-121 406.0 0.6 2.0 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 KEZ40154.1 - 7.1e-32 109.2 29.4 1.6e-19 69.6 5.1 2.8 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KEZ40154.1 - 0.0011 18.2 14.2 0.0042 16.4 0.7 2.8 2 1 0 2 2 2 2 Ion transport protein Aminotran_1_2 PF00155.21 KEZ40155.1 - 6e-34 117.8 0.0 7.6e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEZ40155.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Lactamase_B PF00753.27 KEZ40156.1 - 7.1e-20 71.8 2.5 1e-19 71.3 2.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KEZ40156.1 - 4.7e-05 23.0 0.2 6.8e-05 22.5 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NB-ARC PF00931.22 KEZ40157.1 - 5.9e-06 25.7 0.0 4.3e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KEZ40157.1 - 1.6e-05 25.3 0.0 5e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KEZ40157.1 - 0.0024 18.5 0.0 0.0094 16.6 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ40157.1 - 0.011 15.0 0.0 0.057 12.7 0.0 2.1 3 0 0 3 3 3 0 Serine aminopeptidase, S33 AAA_22 PF13401.6 KEZ40157.1 - 0.016 15.5 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 KEZ40157.1 - 0.029 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) IstB_IS21 PF01695.17 KEZ40157.1 - 0.073 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein PGAP1 PF07819.13 KEZ40157.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_M15_2 PF05951.13 KEZ40158.1 - 0.0053 16.4 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) GFO_IDH_MocA PF01408.22 KEZ40159.1 - 1.4e-07 32.4 0.0 3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ATPgrasp_N PF18130.1 KEZ40160.1 - 5.6e-17 62.1 0.0 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 KEZ40160.1 - 5.5e-09 35.8 0.0 6.6e-08 32.3 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEZ40160.1 - 3e-06 26.9 0.0 6.8e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KEZ40160.1 - 0.0028 17.7 0.0 0.058 13.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KEZ40160.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GSH-S_ATP PF02955.16 KEZ40160.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain CPSase_L_D2 PF02786.17 KEZ40160.1 - 0.023 14.2 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ABC_membrane PF00664.23 KEZ40161.1 - 8.6e-98 327.3 29.6 4.4e-50 170.8 13.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ40161.1 - 1.5e-70 236.1 0.0 1.4e-34 119.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ40161.1 - 1.7e-16 60.3 0.1 2e-05 24.1 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ40161.1 - 2.5e-08 34.5 6.4 0.0013 19.1 0.6 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KEZ40161.1 - 2.1e-07 30.6 0.2 0.025 14.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ40161.1 - 9.3e-07 28.9 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KEZ40161.1 - 2.8e-06 27.7 0.3 0.17 12.1 0.0 4.0 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 KEZ40161.1 - 3.5e-06 26.1 2.5 0.031 13.1 0.1 2.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 KEZ40161.1 - 1.8e-05 24.6 1.8 0.47 10.1 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KEZ40161.1 - 2e-05 24.5 0.0 0.07 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KEZ40161.1 - 0.00017 21.7 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_5 PF07728.14 KEZ40161.1 - 0.00037 20.5 0.1 4.3 7.3 0.0 4.4 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 KEZ40161.1 - 0.0027 17.0 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KEZ40161.1 - 0.0042 17.2 0.1 5.4 7.1 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KEZ40161.1 - 0.0086 15.8 0.0 5.1 6.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEZ40161.1 - 0.0086 15.9 0.3 0.55 10.0 0.1 2.9 3 1 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KEZ40161.1 - 0.0089 16.2 0.0 3.5 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEZ40161.1 - 0.0099 15.4 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KEZ40161.1 - 0.012 16.1 0.1 2 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KEZ40161.1 - 0.013 14.8 0.2 2.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.6 KEZ40161.1 - 0.022 15.0 4.5 3.8 7.8 0.2 4.8 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit TniB PF05621.11 KEZ40161.1 - 0.023 14.1 0.1 31 3.9 0.0 4.0 4 0 0 4 4 4 0 Bacterial TniB protein AAA_25 PF13481.6 KEZ40161.1 - 0.028 14.0 1.1 5.3 6.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 KEZ40161.1 - 0.051 14.1 0.0 14 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KEZ40161.1 - 0.065 13.1 0.0 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 KEZ40161.1 - 0.093 12.5 0.0 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aminotran_3 PF00202.21 KEZ40162.1 - 2.9e-84 283.1 0.0 3.5e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEZ40162.1 - 3.2e-05 23.3 0.0 7.3e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II adh_short PF00106.25 KEZ40163.1 - 1.5e-18 66.9 0.0 6.1e-18 65.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ40163.1 - 2.7e-13 50.0 0.1 3.5e-13 49.7 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEZ40163.1 - 0.00024 20.7 0.0 0.00042 19.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEZ40163.1 - 0.0062 15.7 0.3 0.029 13.5 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KEZ40163.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KEZ40164.1 - 1.8e-61 208.3 0.0 2.3e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OsmC PF02566.19 KEZ40165.1 - 9.8e-17 61.3 0.0 2.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 OsmC-like protein CENP-B_dimeris PF09026.10 KEZ40165.1 - 0.39 11.1 5.4 0.69 10.3 5.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KEZ40165.1 - 2.9 7.1 7.6 4 6.7 7.6 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KEZ40165.1 - 3.9 5.5 6.9 5.2 5.0 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Kelch_4 PF13418.6 KEZ40166.1 - 2.9e-28 97.6 11.3 7.1e-15 54.8 0.1 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KEZ40166.1 - 3.4e-28 97.4 7.3 4.1e-06 26.9 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KEZ40166.1 - 6.4e-15 54.8 5.3 0.00018 21.7 0.1 6.0 4 2 2 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KEZ40166.1 - 1.2e-12 47.2 7.2 0.0014 18.2 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 KEZ40166.1 - 4.1e-10 39.4 1.8 0.098 12.7 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KEZ40166.1 - 7.5e-06 25.7 11.7 0.28 11.2 0.2 6.4 7 1 0 7 7 7 3 Kelch motif Abhydrolase_4 PF08386.10 KEZ40167.1 - 4.6e-24 84.5 0.0 8e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEZ40167.1 - 1e-12 48.2 0.0 7.4e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2181 PF10223.9 KEZ40167.1 - 0.24 10.8 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) MFS_1 PF07690.16 KEZ40168.1 - 2.2e-19 69.6 82.3 1.9e-14 53.4 50.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KEZ40169.1 - 3.9e-23 82.0 37.1 1.2e-11 44.1 7.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 KEZ40169.1 - 2.9 6.1 12.3 0.26 9.5 4.4 2.6 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KEZ40170.1 - 5.5e-38 130.9 0.0 7.3e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KEZ40171.1 - 0 1230.8 0.1 1.1e-80 271.3 0.0 6.3 5 1 1 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KEZ40171.1 - 3.4e-164 546.8 0.0 1.9e-41 142.2 0.0 7.0 5 3 1 6 6 6 6 Condensation domain PP-binding PF00550.25 KEZ40171.1 - 2.8e-63 210.2 3.3 2.1e-09 37.6 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ40171.1 - 3.5e-13 50.3 0.0 0.0063 17.5 0.0 4.8 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KEZ40171.1 - 0.072 12.8 0.0 2.7 7.7 0.0 3.4 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Sugar_tr PF00083.24 KEZ40172.1 - 3.9e-56 190.8 22.0 5.2e-56 190.4 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40172.1 - 2.7e-21 75.9 64.7 3.3e-20 72.3 38.6 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 KEZ40172.1 - 2.3e-18 67.6 0.1 2.3e-18 67.6 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family MFS_2 PF13347.6 KEZ40172.1 - 3.9e-05 22.4 18.7 0.00017 20.3 5.9 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein PGAP1 PF07819.13 KEZ40172.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF4387 PF14330.6 KEZ40173.1 - 2e-33 115.0 0.0 3.9e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 KEZ40173.1 - 1.4e-09 37.2 0.0 2.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 KEZ40174.1 - 7.8e-10 38.2 0.1 1.3e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Matrilin_ccoil PF10393.9 KEZ40174.1 - 0.12 12.2 0.1 0.35 10.8 0.1 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reprolysin_5 PF13688.6 KEZ40175.1 - 1.2e-13 51.7 0.1 1.8e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KEZ40175.1 - 1.1e-09 38.3 0.1 1.5e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KEZ40175.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Fusion_F0 PF13044.6 KEZ40175.1 - 0.015 14.0 0.0 0.019 13.7 0.0 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Reprolysin_3 PF13582.6 KEZ40175.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Fungal_trans_2 PF11951.8 KEZ40176.1 - 1.1e-27 96.9 0.1 6.8e-15 54.8 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40176.1 - 2.3e-07 30.8 11.3 4e-07 30.0 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEZ40177.1 - 3.4e-18 65.8 5.7 1.4e-12 47.2 0.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Aminotran_3 PF00202.21 KEZ40178.1 - 2.3e-66 224.1 0.1 3.3e-66 223.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III FAD_binding_3 PF01494.19 KEZ40179.1 - 4e-16 59.2 1.7 6.4e-15 55.2 1.7 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ40179.1 - 1.8e-07 30.7 0.4 3.6e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ40179.1 - 0.0002 21.8 0.7 0.0006 20.3 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase InPase PF18823.1 KEZ40179.1 - 0.00025 20.8 0.1 0.00043 20.0 0.1 1.3 1 0 0 1 1 1 1 Inorganic Pyrophosphatase DAO PF01266.24 KEZ40179.1 - 0.00087 19.0 0.4 0.0074 15.9 1.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyrophosphatase PF00719.19 KEZ40179.1 - 0.0042 16.9 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Inorganic pyrophosphatase NAD_binding_8 PF13450.6 KEZ40179.1 - 0.021 15.0 0.2 0.062 13.5 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KEZ40179.1 - 0.078 12.6 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_61 PF03443.14 KEZ40180.1 - 1.8e-55 188.1 0.0 2.6e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEZ40180.1 - 7.4e-14 51.4 12.6 2.4e-13 49.8 12.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Git3 PF11710.8 KEZ40181.1 - 6.7e-08 32.5 13.5 1.2e-07 31.7 13.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 KEZ40181.1 - 3.8e-06 26.3 9.6 3.8e-06 26.3 9.6 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KEZ40181.1 - 2.6e-05 23.7 10.4 3.9e-05 23.1 10.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KEZ40181.1 - 0.0013 18.2 10.1 0.002 17.5 10.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx HET PF06985.11 KEZ40181.1 - 0.042 14.2 0.3 0.088 13.2 0.3 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KEZ40182.1 - 2.9e-07 30.5 8.6 5.8e-07 29.5 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 KEZ40183.1 - 0.00012 21.9 0.0 0.00034 20.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GST_N_3 PF13417.6 KEZ40184.1 - 3.7e-11 43.3 0.0 6.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KEZ40184.1 - 3.8e-09 36.8 0.0 1.2e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEZ40184.1 - 2.1e-05 24.7 0.0 4.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ40184.1 - 0.0009 19.2 0.1 0.0021 18.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEZ40184.1 - 0.0098 16.1 0.1 0.023 14.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEZ40185.1 - 2.5e-11 43.7 0.0 5.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEZ40185.1 - 1.8e-09 37.9 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ40185.1 - 4e-09 36.6 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEZ40185.1 - 1.8e-08 34.4 0.0 3.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEZ40185.1 - 4.1e-08 33.1 0.0 8.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEZ40185.1 - 3.9e-07 30.3 0.0 8.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MARVEL PF01284.23 KEZ40186.1 - 0.15 12.1 4.2 0.43 10.6 3.9 2.0 1 1 0 1 1 1 0 Membrane-associating domain PMI_typeI PF01238.21 KEZ40187.1 - 1.8e-45 155.7 0.0 1.7e-31 109.8 0.0 3.0 1 1 1 2 2 2 2 Phosphomannose isomerase type I Beta-lactamase PF00144.24 KEZ40187.1 - 5.2e-45 154.1 0.0 8.5e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KEZ40187.1 - 1.3e-07 32.0 0.4 3.2e-07 30.7 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) DUF3603 PF12227.8 KEZ40187.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) MFS_1 PF07690.16 KEZ40188.1 - 7.4e-36 123.8 76.6 1.2e-31 110.0 43.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ40188.1 - 5.9e-11 41.9 33.2 2.4e-07 30.0 12.4 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter HNH_2 PF13391.6 KEZ40190.1 - 2.4e-12 46.8 0.1 4.8e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease MethyTransf_Reg PF10119.9 KEZ40190.1 - 0.026 15.2 0.8 0.051 14.3 0.8 1.4 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain PGA_cap PF09587.10 KEZ40190.1 - 0.042 13.3 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap AP_endonuc_2 PF01261.24 KEZ40191.1 - 8.7e-34 116.8 0.0 1.2e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FCH PF00611.23 KEZ40191.1 - 0.69 10.2 4.2 9.9 6.5 0.4 3.0 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain AAA_12 PF13087.6 KEZ40192.1 - 2.8e-23 82.6 0.0 4.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ40192.1 - 2.7e-09 37.2 0.0 2.1e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ40192.1 - 2.6e-06 27.3 0.0 0.0064 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ40192.1 - 3.9e-05 23.5 2.1 0.24 11.1 0.1 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KEZ40192.1 - 0.00031 21.1 0.0 0.0012 19.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain Chorion_3 PF05387.11 KEZ40193.1 - 0.96 9.0 8.3 1.2 8.7 8.3 1.0 1 0 0 1 1 1 0 Chorion family 3 TauD PF02668.16 KEZ40194.1 - 1.7e-42 146.1 0.1 2.6e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.11 KEZ40194.1 - 0.02 14.9 0.1 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Ax_dynein_light PF10211.9 KEZ40194.1 - 0.023 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain MFS_1 PF07690.16 KEZ40195.1 - 1.8e-21 76.5 16.4 2.4e-21 76.1 16.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 KEZ40196.1 - 2.3e-130 435.1 0.2 3.5e-130 434.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sulfatase PF00884.23 KEZ40196.1 - 4.4e-59 200.4 0.7 7.7e-59 199.6 0.7 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KEZ40196.1 - 0.0049 17.1 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) MFS_1 PF07690.16 KEZ40197.1 - 3.3e-43 148.0 32.2 1.2e-42 146.1 32.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ40197.1 - 1.3e-07 30.9 8.9 1.3e-07 30.9 8.9 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ40197.1 - 0.021 13.7 13.0 0.047 12.5 6.4 2.5 2 0 0 2 2 2 0 MFS_1 like family Phage_holin_3_2 PF04550.12 KEZ40197.1 - 0.058 13.9 1.5 0.31 11.6 1.5 2.2 1 0 0 1 1 1 0 Phage holin family 2 MtrB PF05440.12 KEZ40197.1 - 0.14 12.6 0.9 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Aminotran_1_2 PF00155.21 KEZ40198.1 - 5.7e-33 114.6 0.0 7.9e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ40198.1 - 0.0096 14.5 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 KEZ40198.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.21 KEZ40199.1 - 2.2e-40 138.6 0.0 1.1e-21 77.1 0.0 3.7 3 1 0 3 3 3 2 Aminotransferase class-III AAA_26 PF13500.6 KEZ40199.1 - 6.4e-18 65.3 0.0 9.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain BTB PF00651.31 KEZ40200.1 - 1.2e-07 31.9 0.0 3.9e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Glyco_hydro_61 PF03443.14 KEZ40202.1 - 2e-68 230.4 0.0 2.6e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.22 KEZ40202.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF4470 PF14737.6 KEZ40203.1 - 4.4e-22 78.1 0.0 8.8e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) PSI_PsaH PF03244.14 KEZ40203.1 - 0.0083 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VI Fungal_lectin PF07938.12 KEZ40204.1 - 5.8e-93 311.6 5.4 6.9e-93 311.3 5.4 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF676 PF05057.14 KEZ40205.1 - 0.061 12.8 0.1 0.17 11.4 0.1 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF3848 PF12959.7 KEZ40205.1 - 0.087 12.9 0.6 0.17 12.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) AAA PF00004.29 KEZ40207.1 - 2.7e-09 37.5 0.1 7.6e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3425 PF11905.8 KEZ40208.1 - 3.5e-16 59.3 3.2 5.4e-16 58.7 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KEZ40208.1 - 0.026 14.6 9.0 0.051 13.7 9.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 KEZ40208.1 - 0.15 12.2 12.3 0.26 11.4 12.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper HALZ PF02183.18 KEZ40208.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper ADH_N PF08240.12 KEZ40209.1 - 1.5e-23 82.8 0.0 2.5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ40209.1 - 4.3e-22 78.5 0.2 6.8e-22 77.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ40209.1 - 0.04 13.3 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldedh PF00171.22 KEZ40210.1 - 3.7e-145 484.0 0.0 4.1e-145 483.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ40210.1 - 0.034 13.6 0.0 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SnoaL_2 PF12680.7 KEZ40211.1 - 0.00012 22.7 0.0 0.00015 22.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_8 PF13450.6 KEZ40212.1 - 7.8e-14 51.7 0.0 1.7e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KEZ40212.1 - 4.4e-13 48.5 0.1 5e-10 38.4 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 KEZ40212.1 - 1.5e-07 31.4 0.0 0.0052 16.4 0.0 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ40212.1 - 9e-07 28.4 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ40212.1 - 2.9e-06 27.4 0.2 0.0024 17.9 0.0 3.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEZ40212.1 - 4.5e-05 22.8 0.0 0.01 15.1 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ40212.1 - 0.00059 19.1 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 KEZ40212.1 - 0.0018 17.5 0.0 13 4.8 0.0 3.7 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KEZ40212.1 - 0.0097 14.6 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 KEZ40212.1 - 0.017 14.8 0.1 0.058 13.0 0.0 2.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 KEZ40212.1 - 0.16 11.0 0.0 0.45 9.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain LBR_tudor PF09465.10 KEZ40212.1 - 0.97 9.3 4.7 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain MFS_1 PF07690.16 KEZ40213.1 - 9.2e-32 110.3 30.2 1.4e-31 109.7 30.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 KEZ40214.1 - 7.1e-63 212.9 0.0 8.5e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2_5_RNA_ligase2 PF13563.6 KEZ40214.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily HET PF06985.11 KEZ40215.1 - 2.6e-25 89.5 0.0 6.9e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAA_hydrolase PF01557.18 KEZ40216.1 - 4.6e-66 222.6 0.0 5.5e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 KEZ40216.1 - 0.015 16.2 0.1 0.068 14.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) OPT PF03169.15 KEZ40220.1 - 4.5e-134 448.4 48.0 5.2e-134 448.2 48.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 KEZ40221.1 - 9.6e-32 110.3 21.5 9.6e-32 110.3 21.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ40221.1 - 4.9e-14 52.1 2.8 4.9e-14 52.1 2.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ40221.1 - 0.00026 19.5 0.9 0.00044 18.8 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1435 PF07256.12 KEZ40221.1 - 3.2 7.9 6.1 46 4.2 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1435) Pyr_redox_3 PF13738.6 KEZ40222.1 - 2.7e-20 72.8 0.0 4.2e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ40222.1 - 5.9e-18 65.1 0.4 3.8e-12 46.0 0.2 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEZ40222.1 - 3.9e-13 48.7 0.2 3.9e-12 45.4 0.2 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEZ40222.1 - 6.5e-11 41.9 2.6 2.1e-07 30.4 0.2 3.1 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KEZ40222.1 - 1.6e-10 41.4 0.0 0.0014 19.1 0.0 3.6 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ40222.1 - 2.2e-07 31.0 0.0 1e-05 25.7 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEZ40222.1 - 6.8e-07 28.9 3.2 7.7e-06 25.4 0.8 2.2 1 1 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KEZ40222.1 - 1.9e-06 28.0 0.1 0.0029 17.7 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 KEZ40222.1 - 2.2e-06 27.5 0.1 0.0075 15.9 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ40222.1 - 1.8e-05 24.8 2.3 1.7 8.6 0.3 3.3 2 1 1 3 3 3 3 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEZ40222.1 - 0.00018 20.7 1.6 0.0023 17.1 0.4 2.9 1 1 2 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 KEZ40222.1 - 0.00087 18.4 0.0 0.0094 15.0 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KEZ40222.1 - 0.0033 16.2 0.2 0.035 12.8 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KEZ40222.1 - 0.0044 16.4 2.6 0.098 12.0 2.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KEZ40222.1 - 0.0097 15.2 0.0 0.81 8.9 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 KEZ40222.1 - 0.014 15.8 0.0 8.9 6.8 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding GIDA PF01134.22 KEZ40222.1 - 0.055 12.6 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Sugar_tr PF00083.24 KEZ40223.1 - 1.2e-48 166.1 19.0 1.8e-48 165.6 19.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40223.1 - 2.9e-21 75.8 40.7 4.8e-20 71.8 22.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KEZ40224.1 - 1.4e-14 53.8 61.6 2.7e-13 49.6 30.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KEZ40224.1 - 0.015 13.8 24.8 0.021 13.2 24.8 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) ABC_tran PF00005.27 KEZ40225.1 - 2e-50 170.9 0.0 1.8e-29 103.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEZ40225.1 - 2.8e-27 96.1 23.7 7e-25 88.2 7.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KEZ40225.1 - 8.6e-12 45.0 2.6 0.00012 21.6 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ40225.1 - 2.9e-07 30.1 1.3 0.0033 17.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KEZ40225.1 - 4.9e-07 29.9 2.0 0.057 13.2 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEZ40225.1 - 8e-07 29.1 0.4 0.0052 16.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEZ40225.1 - 1.1e-06 29.1 0.1 0.084 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ40225.1 - 9.9e-06 25.6 0.0 0.21 11.7 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 KEZ40225.1 - 1.2e-05 25.4 0.1 0.05 13.8 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KEZ40225.1 - 3.2e-05 24.2 5.9 0.051 13.9 0.2 4.0 3 2 0 3 3 3 2 AAA domain cobW PF02492.19 KEZ40225.1 - 0.00021 20.9 0.5 0.033 13.8 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KEZ40225.1 - 0.00024 20.4 2.2 5 6.2 0.2 3.8 3 1 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.6 KEZ40225.1 - 0.0003 21.4 0.4 0.056 13.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ40225.1 - 0.0013 19.2 0.3 3.1 8.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KEZ40225.1 - 0.0018 17.6 0.5 0.41 9.9 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.29 KEZ40225.1 - 0.0027 18.1 1.2 4.3 7.8 0.1 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KEZ40225.1 - 0.0033 16.8 0.7 0.16 11.3 0.1 2.9 2 1 0 2 2 2 1 KaiC FtsK_SpoIIIE PF01580.18 KEZ40225.1 - 0.0034 16.8 0.5 1 8.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_14 PF13173.6 KEZ40225.1 - 0.0039 17.2 0.0 0.34 10.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain Septin PF00735.18 KEZ40225.1 - 0.0039 16.5 0.2 2 7.6 0.0 2.3 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 KEZ40225.1 - 0.0048 16.7 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KEZ40225.1 - 0.0064 16.2 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 KEZ40225.1 - 0.0073 16.2 0.2 1.4 8.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 KEZ40225.1 - 0.0077 16.4 0.7 9.3 6.5 0.0 3.7 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 KEZ40225.1 - 0.0089 15.1 0.1 0.032 13.3 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.14 KEZ40225.1 - 0.01 15.8 0.6 14 5.7 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ40225.1 - 0.011 15.2 0.1 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KEZ40225.1 - 0.015 15.1 0.2 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 KEZ40225.1 - 0.018 14.0 0.1 1.2 8.1 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KEZ40225.1 - 0.02 15.3 0.2 15 6.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase DUF87 PF01935.17 KEZ40225.1 - 0.021 14.9 1.5 0.31 11.1 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 KEZ40225.1 - 0.024 13.6 0.4 0.34 9.8 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 KEZ40225.1 - 0.035 14.1 1.4 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 KEZ40225.1 - 0.04 13.5 0.1 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KEZ40225.1 - 0.052 12.3 3.6 3.6 6.3 0.3 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 KEZ40225.1 - 0.072 12.8 0.2 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KEZ40225.1 - 0.077 12.7 0.2 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KEZ40225.1 - 0.081 12.4 0.1 3.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PRK PF00485.18 KEZ40225.1 - 0.18 11.5 0.3 0.55 9.9 0.1 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 KEZ40225.1 - 0.2 11.5 0.6 23 4.9 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KEZ40225.1 - 0.58 10.1 2.7 7.8 6.4 0.1 2.7 3 0 0 3 3 2 0 NTPase Aminotran_4 PF01063.19 KEZ40226.1 - 6.2e-20 72.0 0.0 7.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 KEZ40227.1 - 5.4e-64 216.6 0.0 7.4e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.13 KEZ40228.1 - 1.2e-64 217.7 8.6 1.5e-64 217.4 8.6 1.1 1 0 0 1 1 1 1 RTA1 like protein HPP PF04982.13 KEZ40228.1 - 0.39 10.9 5.0 0.27 11.4 1.9 2.2 1 1 1 2 2 2 0 HPP family Ank_4 PF13637.6 KEZ40229.1 - 8e-08 32.7 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ40229.1 - 9.9e-07 29.3 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ40229.1 - 1.5e-05 25.0 0.0 0.23 12.1 0.0 2.9 3 0 0 3 3 2 2 Ankyrin repeat Ank PF00023.30 KEZ40229.1 - 0.0052 17.2 0.1 0.98 10.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KEZ40229.1 - 0.0063 16.8 0.0 0.12 12.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HR1 PF02185.16 KEZ40229.1 - 0.019 15.1 3.6 0.033 14.3 3.6 1.3 1 0 0 1 1 1 0 Hr1 repeat PSD5 PF07637.11 KEZ40229.1 - 0.059 13.7 0.8 0.14 12.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) PKcGMP_CC PF16808.5 KEZ40229.1 - 0.085 12.7 3.5 0.17 11.7 3.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 KEZ40229.1 - 0.26 11.7 2.0 0.64 10.4 2.0 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain bZIP_1 PF00170.21 KEZ40229.1 - 0.45 10.6 10.0 0.89 9.7 10.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor RAP1 PF07218.11 KEZ40229.1 - 0.64 8.2 3.6 0.87 7.8 3.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AMP-binding PF00501.28 KEZ40230.1 - 2.7e-292 968.5 0.1 3.7e-77 259.7 0.0 4.4 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KEZ40230.1 - 4.2e-225 747.6 0.0 2.9e-50 171.3 0.0 8.4 7 2 0 7 7 7 7 Condensation domain PP-binding PF00550.25 KEZ40230.1 - 9.1e-39 131.6 0.7 1.7e-09 37.9 0.0 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ40230.1 - 3.7e-11 43.8 0.0 0.14 13.1 0.0 5.0 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 KEZ40230.1 - 0.016 15.0 0.0 13 5.4 0.0 3.4 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.12 KEZ40230.1 - 0.084 11.4 0.2 26 3.2 0.0 4.0 6 0 0 6 6 6 0 Alcohol acetyltransferase Transferase PF02458.15 KEZ40230.1 - 0.11 11.1 0.0 5.1 5.6 0.0 3.3 5 0 0 5 5 5 0 Transferase family 2OG-FeII_Oxy_3 PF13640.6 KEZ40232.1 - 5.1e-08 33.7 0.1 1e-07 32.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dynamin_N PF00350.23 KEZ40233.1 - 2.8e-14 53.5 0.2 6e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEZ40233.1 - 1.2e-13 51.0 0.0 2.1e-13 50.1 0.0 1.4 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KEZ40233.1 - 0.027 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Spc7 PF08317.11 KEZ40235.1 - 2.2e-05 23.5 1.9 2.2e-05 23.5 1.9 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF1116 PF06545.11 KEZ40235.1 - 0.01 15.3 0.3 0.02 14.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) BAG6 PF12057.8 KEZ40235.1 - 0.078 12.7 0.2 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 BCL2-associated athanogene 6 NAD_binding_5 PF07994.12 KEZ40235.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.3 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase Med11 PF10280.9 KEZ40235.1 - 0.15 12.6 3.0 0.32 11.5 0.2 2.3 2 0 0 2 2 2 0 Mediator complex protein APG6_N PF17675.1 KEZ40235.1 - 0.17 12.4 8.1 0.051 14.1 1.6 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF2827 PF10933.8 KEZ40235.1 - 0.2 10.3 0.5 0.41 9.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Swi5 PF07061.11 KEZ40235.1 - 0.3 11.2 3.4 2.7 8.2 0.0 2.9 2 0 0 2 2 2 0 Swi5 V_ATPase_I PF01496.19 KEZ40235.1 - 0.87 7.4 4.4 1.1 7.1 4.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 KEZ40235.1 - 2.2 8.9 8.2 2.5 8.8 0.2 2.5 2 1 0 2 2 2 0 Initiation control protein YabA DUF4446 PF14584.6 KEZ40235.1 - 2.6 8.0 5.6 17 5.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF148 PF02520.17 KEZ40235.1 - 3.9 7.6 9.7 2.6 8.2 0.7 2.9 3 1 0 3 3 3 0 Domain of unknown function DUF148 THOC7 PF05615.13 KEZ40236.1 - 0.036 14.3 0.8 0.036 14.3 0.8 3.2 3 1 0 3 3 3 0 Tho complex subunit 7 LMBR1 PF04791.16 KEZ40236.1 - 0.23 10.3 4.6 0.55 9.1 0.0 2.4 3 0 0 3 3 3 0 LMBR1-like membrane protein DUF4363 PF14276.6 KEZ40236.1 - 0.89 9.7 4.4 0.71 10.0 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) RRF PF01765.19 KEZ40236.1 - 0.98 9.4 0.0 0.98 9.4 0.0 3.6 3 1 0 3 3 3 0 Ribosome recycling factor DUF4695 PF15766.5 KEZ40236.1 - 3.9 7.7 7.3 2.6 8.3 0.4 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4695) 2-Hacid_dh_C PF02826.19 KEZ40237.1 - 1.1e-51 174.7 0.0 4.5e-51 172.7 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KEZ40237.1 - 2.3e-30 105.5 0.0 3.8e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh PF00389.30 KEZ40237.1 - 1.2e-18 67.0 0.0 2.8e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Zn_clus PF00172.18 KEZ40237.1 - 2.4e-06 27.6 10.3 2.4e-06 27.6 10.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VanY PF02557.17 KEZ40237.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase NAD_binding_2 PF03446.15 KEZ40237.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SLATT_6 PF18169.1 KEZ40237.1 - 0.096 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 IlvN PF07991.12 KEZ40237.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain IstB_IS21 PF01695.17 KEZ40238.1 - 1.8e-06 27.8 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein NB-ARC PF00931.22 KEZ40238.1 - 1.1e-05 24.7 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KEZ40238.1 - 9.6e-05 22.8 0.1 0.00042 20.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KEZ40238.1 - 0.072 12.7 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ40238.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KEZ40238.1 - 0.13 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KEZ40238.1 - 0.21 11.6 0.0 14 5.7 0.0 2.5 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain OPT PF03169.15 KEZ40239.1 - 1.6e-81 274.8 42.3 1.8e-81 274.6 42.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 KEZ40239.1 - 0.058 13.7 0.3 0.058 13.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) NACHT PF05729.12 KEZ40240.1 - 7.5e-09 35.7 0.7 1e-07 32.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KEZ40240.1 - 1.1e-05 25.9 0.3 0.00023 21.6 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ40240.1 - 0.00023 21.4 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ40240.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 KEZ40240.1 - 0.0086 16.0 0.0 0.082 12.8 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KEZ40240.1 - 0.015 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ40240.1 - 0.019 15.5 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KEZ40240.1 - 0.027 15.0 0.1 0.11 13.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain Ploopntkinase3 PF18751.1 KEZ40240.1 - 0.041 13.8 0.2 0.83 9.5 0.0 2.9 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 KEZ40240.1 - 0.048 14.2 2.1 0.11 13.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain TFIID_NTD2 PF04494.15 KEZ40240.1 - 0.067 13.4 1.2 5.4 7.3 0.9 2.8 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain DUF3287 PF11690.8 KEZ40240.1 - 0.11 12.2 0.9 0.91 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) T2SSE PF00437.20 KEZ40240.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KEZ40240.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KEZ40240.1 - 0.17 12.3 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 KEZ40240.1 - 0.64 10.1 2.6 7.8 6.5 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain KAP_NTPase PF07693.14 KEZ40240.1 - 0.87 8.8 4.3 16 4.6 0.0 3.4 3 1 1 4 4 4 0 KAP family P-loop domain Trypsin_2 PF13365.6 KEZ40241.1 - 0.00091 20.2 0.1 0.0022 18.9 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain LysM PF01476.20 KEZ40242.1 - 9.6e-33 112.0 9.7 1.2e-06 28.5 0.1 5.2 5 0 0 5 5 5 5 LysM domain HTH_Tnp_1 PF01527.20 KEZ40242.1 - 0.00026 21.3 0.0 2.3 8.6 0.0 3.2 3 0 0 3 3 3 2 Transposase UPF0203 PF05254.12 KEZ40242.1 - 0.031 14.5 9.1 4.2 7.7 0.2 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0203) HTH_28 PF13518.6 KEZ40242.1 - 0.11 12.6 0.0 88 3.3 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain DUF2960 PF11173.8 KEZ40242.1 - 0.14 12.7 0.0 43 4.7 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2960) Pox_A11 PF05061.13 KEZ40242.1 - 0.19 11.0 0.9 12 5.1 0.0 3.3 4 0 0 4 4 4 0 Poxvirus A11 Protein Glyco_hydro_18 PF00704.28 KEZ40243.1 - 8.5e-49 167.0 0.0 1.3e-48 166.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 KEZ40243.1 - 4.1e-26 91.2 1.4 8.2e-26 90.3 0.3 2.2 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.19 KEZ40243.1 - 0.00049 20.5 9.5 0.00049 20.5 9.5 4.1 4 0 0 4 4 4 1 Chitin recognition protein LysM PF01476.20 KEZ40243.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 LysM domain SecE PF00584.20 KEZ40244.1 - 3.8e-14 52.3 0.0 4.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_S3Ae PF01015.18 KEZ40245.1 - 2.4e-89 298.3 2.2 2.9e-89 298.0 2.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ribosomal_L22 PF00237.19 KEZ40245.1 - 0.028 14.7 0.2 0.054 13.7 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e SUI1 PF01253.22 KEZ40245.1 - 0.042 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor SUI1 NEMO PF11577.8 KEZ40245.1 - 0.059 13.4 0.6 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO GTP_CH_N PF12471.8 KEZ40246.1 - 2.1e-69 233.2 0.0 3.3e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KEZ40246.1 - 3.2e-09 36.6 0.0 1.5e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.13 KEZ40247.1 - 4.3e-27 94.0 0.0 5.4e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 KEZ40247.1 - 0.019 15.0 0.5 0.029 14.4 0.5 1.4 1 1 0 1 1 1 0 PHD-finger WAPL PF07814.13 KEZ40248.1 - 1.3e-42 146.0 0.1 1.8e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin tRNA-synt_2b PF00587.25 KEZ40249.1 - 2.1e-35 122.3 0.0 3.1e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KEZ40249.1 - 6.5e-18 64.9 3.4 6.5e-18 64.9 3.4 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Ham1p_like PF01725.16 KEZ40250.1 - 9.7e-42 143.0 0.0 3.8e-41 141.1 0.0 1.7 1 1 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 KEZ40251.1 - 2.6e-28 99.1 0.1 9.4e-28 97.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 KEZ40251.1 - 6.4e-07 29.9 0.4 3.8e-05 24.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 KEZ40251.1 - 6.3e-05 23.1 0.1 0.007 16.5 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 KEZ40251.1 - 0.00017 21.8 0.2 0.00073 19.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ40251.1 - 0.00028 21.1 0.0 0.045 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 KEZ40251.1 - 0.00038 20.4 0.2 0.31 10.9 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA PF00004.29 KEZ40251.1 - 0.00058 20.3 0.0 0.0073 16.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KEZ40251.1 - 0.00066 19.4 0.1 0.95 9.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase SKI PF01202.22 KEZ40251.1 - 0.0012 19.0 0.2 0.013 15.7 0.2 2.0 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.15 KEZ40251.1 - 0.0019 18.2 0.1 0.0039 17.1 0.1 1.6 1 0 0 1 1 1 1 NTPase Hydin_ADK PF17213.3 KEZ40251.1 - 0.0068 16.7 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 KEZ40251.1 - 0.0086 16.4 0.0 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KEZ40251.1 - 0.027 14.3 0.3 0.056 13.2 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KEZ40251.1 - 0.03 14.7 0.2 0.043 14.2 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 KEZ40251.1 - 0.034 13.6 0.0 0.081 12.4 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 KEZ40251.1 - 0.046 13.7 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arnt_C PF18583.1 KEZ40251.1 - 0.058 13.0 0.1 3.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Aminoarabinose transferase C-terminal domain AAA_19 PF13245.6 KEZ40251.1 - 0.076 13.4 1.5 0.46 10.8 0.4 2.2 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEZ40251.1 - 0.078 12.7 0.1 0.21 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 KEZ40251.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.22 KEZ40251.1 - 0.16 12.4 0.1 0.31 11.4 0.0 1.5 2 0 0 2 2 1 0 RNA helicase AAA_30 PF13604.6 KEZ40251.1 - 0.21 11.3 1.5 4.1 7.1 0.4 2.4 2 1 1 3 3 3 0 AAA domain DUF1629 PF07791.11 KEZ40252.1 - 0.056 13.6 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) TPP_enzyme_C PF02775.21 KEZ40253.1 - 9.9e-10 38.4 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAD_binding_4 PF01565.23 KEZ40254.1 - 8.6e-24 83.9 0.0 2e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain MFS_1 PF07690.16 KEZ40255.1 - 4.1e-19 68.7 52.7 2.4e-16 59.6 27.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ40255.1 - 5.1e-14 51.6 15.7 4e-13 48.6 15.7 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_C25_C PF03785.14 KEZ40255.1 - 0.9 9.4 3.4 0.83 9.5 0.2 2.4 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain FAD_binding_4 PF01565.23 KEZ40257.1 - 3.2e-28 98.2 0.0 5.5e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ40257.1 - 0.02 14.5 0.2 0.19 11.3 0.2 2.1 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain DLH PF01738.18 KEZ40258.1 - 1.6e-17 63.8 0.0 2.7e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KEZ40258.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ40258.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Ank_2 PF12796.7 KEZ40259.1 - 6.7e-38 129.2 0.1 4.1e-10 40.1 0.0 5.4 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ40259.1 - 6.1e-32 109.6 0.4 2.2e-07 31.3 0.1 8.3 2 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ40259.1 - 3.9e-31 106.7 3.0 1.1e-05 25.6 0.4 7.1 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ40259.1 - 3.6e-28 94.5 0.2 0.0033 17.8 0.0 10.9 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 KEZ40259.1 - 1.7e-19 69.3 8.5 0.0049 17.3 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat DUF2773 PF10971.8 KEZ40259.1 - 0.076 13.2 0.5 13 6.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2773) KBP_C PF12309.8 KEZ40259.1 - 0.15 11.5 0.4 2.1 7.8 0.1 2.1 2 0 0 2 2 2 0 KIF-1 binding protein C terminal FAD_binding_3 PF01494.19 KEZ40260.1 - 2.7e-88 296.5 0.0 3.6e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEZ40260.1 - 2.8e-56 190.1 0.0 4.8e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KEZ40260.1 - 0.00021 20.5 0.2 0.00034 19.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ40260.1 - 0.00028 20.2 0.2 0.00079 18.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40260.1 - 0.00045 19.0 0.3 0.00081 18.2 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KEZ40260.1 - 0.0014 17.9 0.1 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KEZ40260.1 - 0.0036 16.6 0.1 0.0058 15.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ40260.1 - 0.0048 16.0 0.1 0.0095 15.0 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ40260.1 - 0.048 13.9 0.1 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ40260.1 - 0.054 12.6 0.2 0.096 11.8 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ40260.1 - 0.088 12.1 0.4 0.14 11.5 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEZ40260.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dioxygenase_C PF00775.21 KEZ40261.1 - 1.9e-53 180.6 0.0 2.5e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEZ40261.1 - 3.6e-27 94.0 0.0 5.5e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEZ40261.1 - 5.9e-07 29.7 0.0 5.4e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 KEZ40261.1 - 0.0015 18.9 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) CoA_transf_3 PF02515.17 KEZ40262.1 - 5.2e-41 141.0 0.0 4.9e-40 137.8 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III TRI5 PF06330.11 KEZ40263.1 - 7.4e-14 51.4 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) EcKinase PF02958.20 KEZ40264.1 - 1.5e-15 57.3 0.0 1.3e-10 41.1 0.1 2.2 1 1 1 2 2 2 2 Ecdysteroid kinase APH PF01636.23 KEZ40264.1 - 8.5e-08 32.4 0.4 1.6e-07 31.5 0.4 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KEZ40264.1 - 1.1e-07 31.0 0.1 1.7e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) OTT_1508_deam PF14441.6 KEZ40266.1 - 5.2e-10 39.2 0.3 1.1e-09 38.2 0.3 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase F-box PF00646.33 KEZ40266.1 - 0.0027 17.5 0.0 0.013 15.4 0.0 2.3 1 0 0 1 1 1 1 F-box domain SDA1 PF05285.12 KEZ40266.1 - 0.015 14.7 8.0 0.023 14.2 8.0 1.2 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.7 KEZ40266.1 - 0.12 12.3 2.7 0.64 10.0 0.2 3.5 4 0 0 4 4 4 0 F-box-like Radial_spoke PF04712.12 KEZ40266.1 - 7.8 5.3 14.2 14 4.4 14.2 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein OCD_Mu_crystall PF02423.15 KEZ40267.1 - 1.7e-11 43.6 0.2 3.5e-09 36.0 0.2 2.6 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KEZ40267.1 - 2.1e-06 27.9 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ40267.1 - 0.015 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain XdhC_CoxI PF02625.16 KEZ40267.1 - 0.057 13.6 0.3 0.65 10.2 0.0 2.6 2 0 0 2 2 2 0 XdhC and CoxI family DUF4240 PF14024.6 KEZ40267.1 - 0.11 12.6 0.1 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) Thiolase_N PF00108.23 KEZ40268.1 - 1.7e-71 240.6 5.0 2.3e-71 240.2 5.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ40268.1 - 8e-42 141.8 0.2 1.7e-41 140.7 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KEZ40268.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KEZ40268.1 - 0.29 10.7 6.5 0.37 10.3 2.5 2.4 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain PEMT PF04191.13 KEZ40269.1 - 6.9e-31 106.8 3.2 6.9e-31 106.8 3.2 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase AsnC_trans_reg PF01037.21 KEZ40272.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Flavokinase PF01687.17 KEZ40273.1 - 1.3e-33 115.6 0.0 2.6e-33 114.7 0.0 1.4 2 0 0 2 2 2 1 Riboflavin kinase PAS PF00989.25 KEZ40274.1 - 0.0025 17.8 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KEZ40274.1 - 0.0043 17.1 8.9 0.0043 17.1 8.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 KEZ40275.1 - 1.3e-10 41.2 0.2 1.3e-10 41.2 0.2 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Synaptobrevin PF00957.21 KEZ40275.1 - 0.002 17.9 1.6 0.0035 17.1 1.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Radical_SAM PF04055.21 KEZ40275.1 - 0.08 13.3 0.0 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily Peptidase_M50 PF02163.22 KEZ40275.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M50 DUF4064 PF13273.6 KEZ40275.1 - 0.17 12.1 0.5 0.38 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Protocadherin PF08374.11 KEZ40275.1 - 8.8 6.2 0.0 8.8 6.2 0.0 2.5 2 1 0 2 2 2 0 Protocadherin Transket_pyr PF02779.24 KEZ40276.1 - 2.8e-44 150.9 0.1 4.1e-44 150.4 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KEZ40276.1 - 1.2e-31 109.1 0.0 3.2e-31 107.8 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KEZ40276.1 - 0.011 16.1 0.2 0.039 14.3 0.0 1.9 3 0 0 3 3 3 0 Pyruvate:ferredoxin oxidoreductase core domain II NMO PF03060.15 KEZ40277.1 - 3.5e-58 197.6 0.6 3.2e-57 194.4 0.6 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KEZ40277.1 - 2.5e-14 53.0 0.0 1.1e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEZ40277.1 - 0.00064 18.8 0.6 0.001 18.2 0.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KEZ40277.1 - 0.24 10.8 1.5 0.35 10.3 0.0 2.0 3 0 0 3 3 3 0 Histidine biosynthesis protein Pkinase PF00069.25 KEZ40278.1 - 1.5e-22 80.3 0.0 8.7e-15 54.8 0.0 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40278.1 - 1.2e-05 24.7 0.0 0.14 11.5 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase Tn7_Tnp_TnsA_N PF08722.11 KEZ40278.1 - 0.2 11.8 0.1 6.6 7.0 0.0 2.6 3 0 0 3 3 3 0 TnsA endonuclease N terminal Ribosomal_S7 PF00177.21 KEZ40279.1 - 6.5e-27 94.0 0.0 9.1e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.26 KEZ40280.1 - 5.8e-21 75.5 5.6 2.9e-14 53.8 0.4 3.3 3 1 0 3 3 3 2 Universal stress protein family Caveolin PF01146.17 KEZ40280.1 - 0.19 11.7 0.1 0.34 10.9 0.1 1.3 1 0 0 1 1 1 0 Caveolin RRM_1 PF00076.22 KEZ40282.1 - 4.3e-84 276.3 5.1 5.4e-23 80.6 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KEZ40282.1 - 6.2e-26 90.4 2.8 1.4e-25 89.3 1.5 2.3 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KEZ40282.1 - 3.6e-11 42.7 0.0 0.018 14.7 0.0 5.1 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEZ40282.1 - 1.1e-07 31.6 0.2 0.00033 20.4 0.0 4.2 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KEZ40282.1 - 3.5e-06 27.0 1.0 1.1 9.4 0.0 5.4 4 2 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KEZ40282.1 - 0.00021 21.2 2.8 13 5.9 0.1 4.8 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KEZ40282.1 - 0.0038 17.3 0.6 3.7 7.7 0.1 3.4 3 0 0 3 3 3 1 Limkain b1 YflT PF11181.8 KEZ40282.1 - 0.025 15.1 8.2 0.64 10.6 0.4 3.4 3 0 0 3 3 3 0 Heat induced stress protein YflT DHHA1 PF02272.19 KEZ40282.1 - 7.6 7.0 8.7 1.4 9.3 0.2 3.2 4 0 0 4 4 4 0 DHHA1 domain HECT PF00632.25 KEZ40283.1 - 6.3e-79 265.6 0.0 9.7e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KEZ40283.1 - 0.88 9.5 3.1 2.6 8.1 3.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Glyco_hydro_125 PF06824.11 KEZ40284.1 - 9.2e-179 594.7 0.0 1.1e-178 594.4 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Chrome_Resist PF09828.9 KEZ40284.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromate resistance exported protein Glyco_hydro_92 PF07971.12 KEZ40285.1 - 3.8e-147 491.0 0.1 4.6e-147 490.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KEZ40285.1 - 9.5e-64 215.5 0.1 1.5e-63 214.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain ETF_QO PF05187.13 KEZ40286.1 - 1e-47 160.5 0.3 1.7e-47 159.8 0.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KEZ40286.1 - 1.7e-08 34.5 0.0 1.8e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ40286.1 - 3.3e-08 33.5 0.2 9e-05 22.2 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ40286.1 - 2.7e-05 23.5 0.0 0.0015 17.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KEZ40286.1 - 3.6e-05 23.2 0.0 0.00012 21.4 0.1 1.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ40286.1 - 4.6e-05 22.7 0.3 0.0041 16.3 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KEZ40286.1 - 0.00012 22.5 0.1 0.19 12.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ40286.1 - 0.00017 20.9 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ40286.1 - 0.00024 19.9 0.5 0.00036 19.3 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KEZ40286.1 - 0.0007 19.1 0.0 0.00097 18.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KEZ40286.1 - 0.0041 16.0 0.0 0.1 11.4 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KEZ40286.1 - 0.0063 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEZ40286.1 - 0.0072 15.6 0.3 0.011 15.0 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 KEZ40286.1 - 0.036 14.7 0.5 0.098 13.3 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 KEZ40286.1 - 0.048 12.7 0.2 0.07 12.2 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KEZ40286.1 - 0.064 12.3 0.1 0.093 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 KEZ40286.1 - 0.12 12.6 0.6 0.33 11.1 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain AlaDh_PNT_C PF01262.21 KEZ40286.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TBP PF00352.21 KEZ40287.1 - 1.5e-67 223.6 0.1 7e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KEZ40287.1 - 0.00012 22.1 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KEZ40287.1 - 0.13 12.1 0.1 0.67 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Fungal_trans PF04082.18 KEZ40288.1 - 0.0003 19.9 0.3 0.0012 18.0 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.25 KEZ40290.1 - 1.2e-38 132.2 0.1 1.6e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ40290.1 - 3.9e-13 49.6 0.0 0.00017 21.8 0.0 3.9 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KEZ40290.1 - 2.1e-06 28.5 0.0 0.02 15.7 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KEZ40290.1 - 4.7e-05 23.3 0.3 0.51 10.3 0.0 3.9 4 0 0 4 4 4 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KEZ40290.1 - 0.00031 20.9 0.0 2 8.5 0.0 3.3 2 1 1 3 3 3 2 Glyoxalase-like domain TRI9 PF08195.11 KEZ40290.1 - 0.059 13.3 0.1 6.5 6.7 0.0 2.3 2 0 0 2 2 2 0 TRI9 protein CppA_N PF14506.6 KEZ40290.1 - 0.088 12.9 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 CppA N-terminal DUF1338 PF07063.13 KEZ40290.1 - 0.21 10.7 0.0 33 3.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1338) 2-Hacid_dh_C PF02826.19 KEZ40291.1 - 2e-54 183.7 0.1 3.2e-54 183.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEZ40291.1 - 1.6e-35 121.7 0.5 4.1e-35 120.4 0.5 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KEZ40291.1 - 0.00038 20.2 0.2 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 KEZ40291.1 - 0.018 15.5 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 KEZ40291.1 - 0.019 15.1 0.1 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KEZ40291.1 - 0.1 13.0 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF21 PF01595.20 KEZ40292.1 - 5.5e-33 114.1 0.2 9.8e-33 113.3 0.2 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KEZ40292.1 - 0.00014 22.2 0.2 0.31 11.5 0.0 3.9 3 1 1 4 4 4 2 CBS domain Ysc84 PF04366.12 KEZ40293.1 - 8.3e-42 142.0 0.3 1.3e-41 141.4 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KEZ40293.1 - 2.7e-15 55.7 0.0 5.7e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KEZ40293.1 - 1.5e-12 47.0 0.0 3.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KEZ40293.1 - 2.2e-12 46.6 0.0 3.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KEZ40293.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Synaptobrevin PF00957.21 KEZ40294.1 - 0.0075 16.0 0.8 0.3 10.9 0.1 2.0 1 1 1 2 2 2 2 Synaptobrevin Phage_holin_2_4 PF16082.5 KEZ40294.1 - 0.045 13.5 0.3 0.094 12.5 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like ArfGap PF01412.18 KEZ40295.1 - 2.8e-41 140.3 0.9 4.3e-41 139.7 0.9 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ish1 PF10281.9 KEZ40295.1 - 0.2 12.0 1.4 5.9 7.3 0.5 2.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SelR PF01641.18 KEZ40296.1 - 7.3e-49 164.9 0.1 8.9e-49 164.6 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 KEZ40296.1 - 0.03 14.5 0.2 0.076 13.2 0.2 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 KEZ40296.1 - 0.037 14.0 0.4 4.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KEZ40296.1 - 0.064 13.0 0.2 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Importin_rep PF18773.1 KEZ40296.1 - 0.16 11.7 0.3 0.34 10.6 0.3 1.6 1 0 0 1 1 1 0 Importin 13 repeat ARID PF01388.21 KEZ40297.1 - 5.4e-17 62.2 0.0 1.2e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain KH_1 PF00013.29 KEZ40298.1 - 7.1e-94 307.7 33.1 3.9e-13 49.0 0.2 14.3 14 2 0 14 14 14 9 KH domain KH_2 PF07650.17 KEZ40298.1 - 2e-11 43.6 22.8 0.036 13.9 0.1 8.1 6 1 1 8 8 8 4 KH domain SLS PF14611.6 KEZ40298.1 - 1.2e-10 41.6 8.8 0.053 13.3 0.3 6.9 4 1 0 5 5 5 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 KEZ40298.1 - 0.0027 17.6 0.2 0.0027 17.6 0.2 5.5 7 0 0 7 7 7 1 KH domain DUF3813 PF12758.7 KEZ40298.1 - 0.017 15.4 0.4 0.092 13.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) BON PF04972.17 KEZ40298.1 - 0.018 15.3 4.0 8.6 6.8 0.0 5.0 5 0 0 5 5 5 0 BON domain PHA_gran_rgn PF09650.10 KEZ40298.1 - 0.038 14.3 1.9 81 3.6 0.0 5.0 5 0 0 5 5 5 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) DUF211 PF02680.14 KEZ40298.1 - 0.16 12.2 1.2 3.7 7.8 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 Pkinase PF00069.25 KEZ40299.1 - 1.6e-70 237.5 0.0 2.3e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40299.1 - 5.2e-46 157.0 0.0 8.2e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ40299.1 - 8.8e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 KEZ40299.1 - 2.1e-06 28.0 1.9 4.2e-05 23.8 1.9 2.6 1 1 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KEZ40299.1 - 6.5e-06 25.2 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEZ40299.1 - 0.074 12.4 0.1 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ40299.1 - 0.11 12.4 1.0 0.24 11.3 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEZ40299.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KEZ40299.1 - 0.2 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 VHS PF00790.19 KEZ40300.1 - 4.7e-41 139.9 3.2 2.2e-40 137.8 0.2 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KEZ40300.1 - 3.7e-15 55.8 4.4 6.7e-15 55.0 4.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KEZ40300.1 - 1.3e-07 31.1 13.2 0.0013 18.5 2.9 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 KEZ40300.1 - 3.8e-05 23.9 0.0 0.00014 22.1 0.0 2.1 1 0 0 1 1 1 1 GAT domain FYVE_2 PF02318.16 KEZ40300.1 - 0.085 13.1 1.6 0.18 12.0 1.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Fer4_2 PF12797.7 KEZ40300.1 - 2 8.7 8.2 2.5 8.4 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 KEZ40301.1 - 1.9e-29 102.9 0.0 3.5e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ40301.1 - 1.2e-20 74.4 0.0 1.6e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KEZ40301.1 - 3.4e-08 34.0 0.0 7.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Spt20 PF12090.8 KEZ40301.1 - 0.043 13.4 5.6 0.093 12.3 5.6 1.5 1 0 0 1 1 1 0 Spt20 family AMP-binding PF00501.28 KEZ40302.1 - 1.2e-84 284.3 0.0 1.6e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Organ_specific PF10950.8 KEZ40302.1 - 0.033 14.9 0.1 0.071 13.8 0.1 1.5 1 0 0 1 1 1 0 Organ specific protein HSP70 PF00012.20 KEZ40303.1 - 9.6e-264 876.1 11.3 1.1e-263 875.9 11.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ40303.1 - 2.8e-17 62.5 3.8 3.5e-16 58.9 1.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KEZ40303.1 - 0.00093 19.6 4.6 3.8 8.0 0.2 3.7 3 1 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 KEZ40303.1 - 0.028 13.9 0.3 1 8.8 0.1 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 KEZ40303.1 - 0.12 11.6 3.1 0.59 9.3 0.2 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase GTP_EFTU PF00009.27 KEZ40304.1 - 9.1e-47 159.1 0.1 2.3e-46 157.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KEZ40304.1 - 5.1e-27 94.0 1.9 5.7e-14 52.2 0.0 2.4 1 1 1 2 2 2 2 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KEZ40304.1 - 1e-10 41.9 0.1 2.7e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KEZ40304.1 - 1.3e-07 31.7 0.0 1.9e-06 27.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KEZ40304.1 - 0.0098 15.3 0.0 1.1 8.6 0.0 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KEZ40304.1 - 0.011 16.0 0.1 0.88 9.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KEZ40304.1 - 0.061 12.8 0.2 1.4 8.4 0.1 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 KEZ40304.1 - 0.2 11.4 1.3 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ40304.1 - 0.4 10.6 1.3 3.8 7.4 0.1 2.8 2 1 0 3 3 3 0 RsgA GTPase Cpn60_TCP1 PF00118.24 KEZ40305.1 - 1.1e-158 528.9 3.6 1.4e-158 528.6 3.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 KEZ40305.1 - 0.18 12.0 1.5 8 6.6 0.1 3.1 3 0 0 3 3 3 0 Enolase, N-terminal domain Pkinase PF00069.25 KEZ40307.1 - 6.1e-14 52.0 0.0 7.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40307.1 - 0.0048 16.2 0.1 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3295 PF11702.8 KEZ40308.1 - 1.2e-132 443.8 33.6 4e-130 435.5 33.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KEZ40308.1 - 9.4e-08 31.8 2.4 1.8e-07 30.9 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CENP-B_dimeris PF09026.10 KEZ40308.1 - 0.29 11.5 9.4 0.72 10.3 9.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FGGY_C PF02782.16 KEZ40309.1 - 6e-72 241.5 2.2 6e-72 241.5 2.2 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEZ40309.1 - 2.9e-61 207.1 0.0 3.9e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NTP_transferase PF00483.23 KEZ40310.1 - 1.6e-52 178.6 0.0 3.6e-52 177.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KEZ40310.1 - 2.9e-16 58.5 13.9 1e-09 37.7 2.2 3.8 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KEZ40310.1 - 3.2e-11 43.8 0.0 4.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KEZ40310.1 - 5.7e-07 29.2 8.0 6.8e-06 25.7 0.8 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KEZ40310.1 - 0.00054 18.2 0.1 0.0015 16.8 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) Prenyltrans PF00432.21 KEZ40311.1 - 1.2e-25 89.0 22.3 9.9e-10 38.0 0.5 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KEZ40311.1 - 0.002 17.3 0.1 0.95 8.5 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain Zn_clus PF00172.18 KEZ40312.1 - 0.0038 17.3 7.7 0.008 16.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.23 KEZ40313.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KEZ40313.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KEZ40313.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KEZ40313.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KEZ40313.1 - 3.1e-15 56.3 7.7 0.029 14.7 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEZ40313.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KEZ40313.1 - 5.6e-13 49.3 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KEZ40313.1 - 5.6e-11 42.5 0.7 0.58 10.0 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KEZ40313.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KEZ40313.1 - 3.1e-06 26.7 0.5 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KEZ40313.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 KEZ40313.1 - 7.2e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KEZ40313.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 KEZ40313.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KEZ40313.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KEZ40313.1 - 0.00037 20.0 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 KEZ40313.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 KEZ40313.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 KEZ40313.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 KEZ40313.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 KEZ40313.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KEZ40313.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 KEZ40313.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 KEZ40313.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 KEZ40313.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 KEZ40313.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 KEZ40313.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Ank_2 PF12796.7 KEZ40314.1 - 3.2e-54 181.4 5.4 2.9e-12 47.0 0.0 10.0 9 2 1 10 10 9 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ40314.1 - 9.3e-50 166.4 10.2 2.4e-09 37.5 0.1 12.9 9 5 5 14 14 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ40314.1 - 2.3e-43 145.7 16.5 1.2e-08 35.1 0.2 12.0 9 3 3 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ40314.1 - 3.1e-39 128.5 25.2 6.3e-05 23.1 0.0 16.8 19 1 0 19 19 18 7 Ankyrin repeat Ank PF00023.30 KEZ40314.1 - 4.8e-33 112.2 24.8 1.4e-07 31.7 0.2 13.1 15 0 0 15 15 13 8 Ankyrin repeat NACHT PF05729.12 KEZ40314.1 - 6.2e-08 32.7 0.1 1.8e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ40314.1 - 8.4e-05 22.9 0.0 0.00034 20.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ40314.1 - 0.00014 21.1 0.0 0.00029 20.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KEZ40314.1 - 0.00019 21.9 0.0 0.0007 20.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KEZ40314.1 - 0.00077 19.8 0.0 0.004 17.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase Helo_like_N PF17111.5 KEZ40314.1 - 0.00079 18.9 2.3 0.0025 17.2 0.7 2.4 2 1 1 3 3 3 1 Fungal N-terminal domain of STAND proteins AAA_14 PF13173.6 KEZ40314.1 - 0.0025 17.8 0.0 0.029 14.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KEZ40314.1 - 0.0038 17.2 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KEZ40314.1 - 0.048 13.2 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KEZ40314.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phage-MuB_C PF09077.11 KEZ40314.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Mu B transposition protein, C terminal AAA PF00004.29 KEZ40314.1 - 0.16 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BRAP2 PF07576.12 KEZ40315.1 - 3.6e-21 75.2 0.0 7.2e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KEZ40315.1 - 9.2e-17 61.1 2.2 2.6e-16 59.7 2.2 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BST2 PF16716.5 KEZ40315.1 - 0.042 14.4 1.0 0.042 14.4 1.0 3.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Filament PF00038.21 KEZ40315.1 - 0.094 12.3 15.2 0.14 11.7 15.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein Exonuc_VII_L PF02601.15 KEZ40315.1 - 2.5 7.6 8.5 3.8 7.0 8.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit T3SSipB PF16535.5 KEZ40315.1 - 3.1 8.2 12.6 2.6 8.5 10.7 1.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4666 PF15697.5 KEZ40315.1 - 3.5 8.3 0.0 3.5 8.3 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4666) Acyltransferase PF01553.21 KEZ40316.1 - 1.3e-10 41.0 0.0 1.8e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Sugar_tr PF00083.24 KEZ40318.1 - 1.2e-17 63.9 19.9 2.4e-12 46.5 11.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40318.1 - 6.2e-08 32.0 16.4 1.4e-05 24.2 0.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Suc_Fer-like PF06999.12 KEZ40319.1 - 1.2e-69 234.1 0.0 1.5e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer4_13 PF13370.6 KEZ40319.1 - 0.084 13.4 0.7 0.19 12.3 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I adh_short PF00106.25 KEZ40320.1 - 0.046 13.2 0.0 7.1 6.0 0.0 2.9 2 1 0 3 3 3 0 short chain dehydrogenase MFS_1 PF07690.16 KEZ40321.1 - 2.2e-20 72.9 32.3 2.2e-20 72.9 32.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UCR_hinge PF02320.16 KEZ40322.1 - 5.4e-26 90.6 9.2 5.4e-26 90.6 9.2 1.7 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 KEZ40322.1 - 0.034 14.0 9.0 0.044 13.7 9.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PTPRCAP PF15713.5 KEZ40322.1 - 0.049 13.9 13.0 0.068 13.5 13.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3530 PF12048.8 KEZ40322.1 - 0.11 11.9 4.4 0.13 11.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FAM176 PF14851.6 KEZ40322.1 - 0.12 12.0 5.8 0.14 11.9 5.8 1.2 1 0 0 1 1 1 0 FAM176 family DUF1115 PF06544.12 KEZ40322.1 - 0.18 11.9 3.1 0.21 11.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) DUF2052 PF09747.9 KEZ40322.1 - 0.22 11.6 12.8 0.27 11.4 12.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) BSP_II PF05432.11 KEZ40322.1 - 0.28 10.8 14.8 0.29 10.8 14.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF913 PF06025.12 KEZ40322.1 - 0.39 9.7 3.1 0.39 9.6 3.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 KEZ40322.1 - 1.1 8.4 10.4 1.1 8.3 10.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3391 PF11871.8 KEZ40322.1 - 1.2 9.7 8.3 1.7 9.2 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) RR_TM4-6 PF06459.12 KEZ40322.1 - 1.3 8.8 9.1 1.4 8.7 9.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TLP-20 PF06088.11 KEZ40322.1 - 1.5 8.7 5.1 1.8 8.4 5.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RRN3 PF05327.11 KEZ40322.1 - 1.7 7.1 5.9 1.9 7.0 5.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EBV-NA3 PF05009.12 KEZ40322.1 - 2 7.9 9.5 3 7.3 9.5 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Tim54 PF11711.8 KEZ40322.1 - 2.4 6.9 7.9 2.6 6.7 7.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2457 PF10446.9 KEZ40322.1 - 2.8 7.0 16.7 2.6 7.1 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.14 KEZ40322.1 - 3 7.6 11.8 3.4 7.4 11.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 KEZ40322.1 - 3.5 5.7 14.4 3.4 5.7 14.4 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KEZ40322.1 - 3.7 6.2 4.3 4 6.1 4.3 1.0 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 KEZ40322.1 - 3.9 6.4 13.7 4.3 6.2 13.7 1.1 1 0 0 1 1 1 0 Paf1 Sporozoite_P67 PF05642.11 KEZ40322.1 - 4.7 5.2 5.6 4.8 5.2 5.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Adeno_terminal PF02459.15 KEZ40322.1 - 5.2 5.3 7.5 5.4 5.3 7.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CDC45 PF02724.14 KEZ40322.1 - 5.3 5.2 10.6 5.4 5.2 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KEZ40322.1 - 6.7 4.7 18.4 7.2 4.6 18.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF740 PF05340.12 KEZ40322.1 - 7.7 5.1 9.2 8 5.1 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RraA-like PF03737.15 KEZ40324.1 - 8.2e-27 94.2 0.1 1.1e-26 93.8 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA Drf_GBD PF06371.13 KEZ40325.1 - 2.4e-13 50.1 2.5 9.6e-12 44.9 2.5 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Pkinase PF00069.25 KEZ40326.1 - 8.1e-08 31.9 0.0 1.7e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40326.1 - 0.17 11.1 0.0 0.48 9.7 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase DNA_pol_phi PF04931.13 KEZ40326.1 - 8 4.4 8.2 13 3.7 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi KCH PF16944.5 KEZ40327.1 - 3.2e-90 302.3 5.8 3.8e-90 302.1 5.8 1.1 1 0 0 1 1 1 1 Fungal potassium channel Putative_PNPOx PF01243.20 KEZ40328.1 - 6.1e-10 39.2 0.0 8.6e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Chromo_shadow PF01393.19 KEZ40329.1 - 1.2e-20 73.4 3.4 7.5e-17 61.2 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KEZ40329.1 - 7.2e-14 51.4 4.2 8.7e-14 51.2 0.3 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Nucleo_P87 PF07267.11 KEZ40329.1 - 0.41 9.4 7.5 0.16 10.8 4.9 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DNA_ligase_A_N PF04675.14 KEZ40330.1 - 0.056 13.8 0.1 0.069 13.5 0.1 1.1 1 0 0 1 1 1 0 DNA ligase N terminus DUF775 PF05603.12 KEZ40330.1 - 0.068 12.7 0.3 0.083 12.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) zf-C2H2_11 PF16622.5 KEZ40331.1 - 0.09 12.6 0.2 0.27 11.0 0.2 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type Pex14_N PF04695.13 KEZ40331.1 - 6.8 7.3 44.0 0.033 14.8 14.7 3.6 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 KEZ40331.1 - 7.9 6.5 34.9 0.044 13.8 12.9 3.1 3 0 0 3 3 3 0 Telomere-associated protein TERB2 CTP_transf_like PF01467.26 KEZ40332.1 - 2.1e-05 24.8 0.0 2.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF3114 PF11311.8 KEZ40332.1 - 0.049 13.2 0.0 2.9 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3114) tRNA-synt_2 PF00152.20 KEZ40333.1 - 1.4e-72 244.4 0.2 1.9e-72 244.0 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEZ40333.1 - 1.5e-11 44.1 0.1 5.2e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEZ40333.1 - 4.8e-07 29.5 0.0 0.0029 17.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) COX15-CtaA PF02628.15 KEZ40334.1 - 9.5e-106 353.5 9.7 1.2e-105 353.2 9.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Utp14 PF04615.13 KEZ40335.1 - 1.4e-188 629.1 63.0 1.4e-188 629.1 63.0 2.1 1 1 1 2 2 2 1 Utp14 protein Na_Ca_ex PF01699.24 KEZ40336.1 - 2.1e-45 154.4 28.7 1.2e-22 80.5 15.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro81C PF17652.1 KEZ40337.1 - 1.2e-160 534.5 5.9 1.5e-160 534.2 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KEZ40337.1 - 9.6e-116 386.4 0.1 2.2e-115 385.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Stn1 PF10451.9 KEZ40338.1 - 2.4e-10 39.8 0.4 2.5e-09 36.5 0.4 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 HMGL-like PF00682.19 KEZ40339.1 - 6e-80 268.6 0.3 1.1e-79 267.7 0.3 1.4 1 0 0 1 1 1 1 HMGL-like DnaJ PF00226.31 KEZ40340.1 - 7.4e-22 77.2 0.6 1.7e-21 76.1 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain GMC_oxred_N PF00732.19 KEZ40341.1 - 8.4e-53 179.7 0.0 1.1e-52 179.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ40341.1 - 1.2e-29 103.7 0.0 2.3e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KEZ40341.1 - 1.1e-08 35.1 0.4 2.2e-08 34.1 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ40341.1 - 1.2e-06 27.9 0.7 0.00013 21.2 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEZ40341.1 - 0.0006 20.0 0.5 0.0084 16.3 0.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ40341.1 - 0.0017 17.6 1.3 0.0027 17.0 0.4 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ40341.1 - 0.0019 17.5 0.2 0.0089 15.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40341.1 - 0.006 15.3 0.1 0.15 10.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KEZ40341.1 - 0.013 14.5 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KEZ40341.1 - 0.017 14.4 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KEZ40341.1 - 0.027 14.7 0.2 0.066 13.5 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KEZ40341.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 KEZ40342.1 - 1.9e-38 132.3 58.4 1.5e-37 129.4 53.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ40342.1 - 9e-16 57.4 26.4 1.7e-15 56.5 26.4 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEZ40342.1 - 0.0079 14.5 1.4 0.0079 14.5 1.4 3.0 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_3_6 PF07332.11 KEZ40342.1 - 0.041 13.9 0.9 0.041 13.9 0.9 5.2 2 2 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Piwi PF02171.17 KEZ40343.1 - 3e-73 246.7 0.0 4.1e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KEZ40343.1 - 1.3e-10 42.0 0.0 2.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KEZ40343.1 - 1.7e-10 40.4 0.1 4e-10 39.2 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KEZ40343.1 - 1.3e-08 34.7 0.0 2.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KEZ40343.1 - 2.9e-08 33.9 0.0 1e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 KEZ40343.1 - 0.00065 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute A_deaminase PF00962.22 KEZ40344.1 - 2e-25 89.8 0.0 1.5e-20 73.8 0.0 2.5 2 0 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KEZ40344.1 - 0.096 13.0 0.2 0.49 10.7 0.2 2.2 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal DUF2076 PF09849.9 KEZ40345.1 - 0.038 14.0 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4133 PF13571.6 KEZ40345.1 - 4 7.8 5.3 0.91 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) zf-C3HC PF07967.13 KEZ40346.1 - 6.2e-39 133.1 0.3 2.5e-34 118.2 0.2 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KEZ40346.1 - 3.6e-27 94.4 1.4 2.1e-26 91.9 0.1 2.4 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.21 KEZ40346.1 - 0.00031 21.3 0.1 0.0094 16.6 0.1 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain HET PF06985.11 KEZ40348.1 - 1.6e-18 67.5 0.1 2.1e-16 60.6 0.0 3.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AAA_23 PF13476.6 KEZ40348.1 - 8.7 6.8 8.6 31 5.0 8.6 1.9 1 1 0 1 1 1 0 AAA domain VHS PF00790.19 KEZ40349.1 - 1.8e-23 83.0 0.0 8.2e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KEZ40349.1 - 2.5e-08 34.1 1.4 6.4e-08 32.8 1.4 1.7 1 0 0 1 1 1 1 GAT domain zf-C2H2 PF00096.26 KEZ40350.1 - 1.2e-21 75.8 28.8 1.8e-05 24.9 0.2 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ40350.1 - 2.8e-18 65.4 26.2 6.2e-06 26.4 1.6 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ40350.1 - 1.1e-12 47.6 24.3 0.0012 19.5 2.2 5.3 6 0 0 6 6 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ40350.1 - 4.5e-09 36.4 0.8 0.4 11.0 0.0 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ40350.1 - 9.8e-05 22.6 9.6 2.1 8.8 0.0 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KEZ40350.1 - 0.00041 20.2 5.5 0.032 14.1 0.5 3.1 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KEZ40350.1 - 0.0046 16.7 10.8 0.025 14.3 2.1 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_UBZ PF18439.1 KEZ40350.1 - 0.013 15.1 2.8 3.6 7.3 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger FOXP-CC PF16159.5 KEZ40350.1 - 0.099 13.3 2.0 21 5.9 0.1 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain DUF2072 PF09845.9 KEZ40350.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein zf-TRAF PF02176.18 KEZ40350.1 - 0.26 12.0 9.4 6.2 7.6 1.3 2.9 2 1 1 3 3 2 0 TRAF-type zinc finger DUF2256 PF10013.9 KEZ40350.1 - 1.2 9.3 6.6 33 4.7 0.1 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) ADK_lid PF05191.14 KEZ40350.1 - 1.5 8.8 9.4 7.3 6.7 1.3 3.3 2 1 1 3 3 3 0 Adenylate kinase, active site lid HNH PF01844.23 KEZ40350.1 - 2.9 8.1 9.8 10 6.4 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease IBR PF01485.21 KEZ40350.1 - 5.7 7.2 9.0 11 6.4 0.7 3.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 KEZ40350.1 - 5.9 7.1 10.1 21 5.3 1.1 3.2 1 1 2 3 3 3 0 Zinc ribbon domain XPA_N PF01286.18 KEZ40350.1 - 9.5 6.4 6.8 4.9 7.3 0.4 3.2 4 0 0 4 4 4 0 XPA protein N-terminal Cyt-b5 PF00173.28 KEZ40351.1 - 2.2e-22 79.0 0.1 2.9e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-actin_cap_A PF01267.17 KEZ40352.1 - 6.1e-99 330.8 0.0 6.8e-99 330.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CSTF2_hinge PF14327.6 KEZ40352.1 - 0.0095 16.4 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 ACAS_N PF16177.5 KEZ40352.1 - 0.017 15.0 0.1 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Citrate_synt PF00285.21 KEZ40352.1 - 0.061 12.4 0.1 0.089 11.8 0.1 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain DUF3822 PF12864.7 KEZ40352.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) DUF2461 PF09365.10 KEZ40353.1 - 1.4e-57 195.0 0.8 4.3e-55 186.9 0.8 2.2 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CD99L2 PF12301.8 KEZ40353.1 - 7.9 6.7 12.6 13 6.0 12.6 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 Nop14 PF04147.12 KEZ40353.1 - 8.3 4.5 17.0 9.7 4.3 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family TPR_1 PF00515.28 KEZ40354.1 - 1.3e-29 100.7 0.4 5.8e-05 22.7 0.0 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ40354.1 - 7.3e-26 88.2 16.5 0.00055 19.8 0.0 10.7 12 1 0 12 12 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ40354.1 - 3.7e-24 84.7 10.4 6.6e-16 58.3 0.3 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KEZ40354.1 - 9.5e-21 72.7 20.3 6.4e-05 23.4 0.0 10.1 6 1 4 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ40354.1 - 1.2e-19 69.7 4.2 0.00056 19.5 0.0 6.9 5 1 2 7 7 7 5 TPR repeat TPR_8 PF13181.6 KEZ40354.1 - 1.1e-18 65.9 0.2 0.0094 16.1 0.0 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ40354.1 - 1.5e-18 67.0 7.9 0.00014 22.3 0.0 8.9 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ40354.1 - 3.8e-14 53.1 21.4 3.5e-09 37.2 0.5 6.6 5 3 2 7 7 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ40354.1 - 2e-13 50.4 18.7 2.3e-05 24.6 0.1 6.8 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ40354.1 - 1.1e-10 41.2 0.1 0.26 11.8 0.0 7.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ40354.1 - 4.6e-09 35.7 2.7 0.14 12.2 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ40354.1 - 2e-08 34.2 11.0 0.0035 17.5 0.1 5.8 4 2 3 7 7 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ40354.1 - 5.6e-07 29.1 7.0 0.00018 20.8 1.4 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ40354.1 - 3.7e-06 27.2 15.3 1.1 10.1 0.0 8.0 9 1 1 10 10 9 2 Tetratricopeptide repeat FAT PF02259.23 KEZ40354.1 - 6.3e-06 25.6 0.2 0.0049 16.1 0.4 2.7 1 1 1 2 2 2 2 FAT domain SNAP PF14938.6 KEZ40354.1 - 0.0018 17.8 3.1 0.59 9.5 0.0 2.7 3 1 0 3 3 2 2 Soluble NSF attachment protein, SNAP PPTA PF01239.22 KEZ40354.1 - 0.0061 16.2 0.2 0.62 9.9 0.0 3.3 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.6 KEZ40354.1 - 0.0097 16.0 5.4 23 5.2 0.1 6.0 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 KEZ40354.1 - 0.032 13.9 0.2 0.29 10.8 0.0 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 KEZ40354.1 - 0.093 12.8 0.4 2.3 8.3 0.0 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) DUF4192 PF13830.6 KEZ40354.1 - 0.18 11.9 7.0 2.1 8.3 3.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) TPR_10 PF13374.6 KEZ40354.1 - 0.31 11.0 9.0 7.1 6.6 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 KEZ40354.1 - 1.9 9.0 13.9 0.45 10.9 0.7 4.0 3 1 1 4 4 4 0 Bacterial transcriptional activator domain PTCB-BRCT PF12738.7 KEZ40355.1 - 2.8e-29 100.8 0.1 1e-18 67.0 0.2 4.6 4 0 0 4 4 4 3 twin BRCT domain RTT107_BRCT_5 PF16770.5 KEZ40355.1 - 2.7e-27 94.6 0.0 2.3e-25 88.4 0.0 3.2 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 KEZ40355.1 - 4.6e-25 87.8 0.0 4.3e-09 36.6 0.0 6.3 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEZ40355.1 - 3.5e-19 69.0 0.0 7.8e-05 23.0 0.0 6.1 6 0 0 6 6 6 3 BRCT domain, a BRCA1 C-terminus domain Lactonase PF10282.9 KEZ40355.1 - 7.5e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller LIG3_BRCT PF16759.5 KEZ40355.1 - 5.3e-08 33.0 0.0 0.096 13.0 0.0 4.6 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KEZ40355.1 - 0.00029 20.9 0.0 2.7 8.1 0.0 3.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.12 KEZ40356.1 - 1.9e-55 186.9 0.1 3.3e-55 186.2 0.1 1.4 1 0 0 1 1 1 1 ESCRT-II complex subunit HLH PF00010.26 KEZ40357.1 - 3.1e-17 62.3 0.9 5.9e-17 61.4 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT_CC PF16559.5 KEZ40357.1 - 7 6.6 7.0 4.9 7.1 0.2 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor UvrD-helicase PF00580.21 KEZ40358.1 - 3.6e-59 200.8 0.1 1e-56 192.7 0.0 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KEZ40358.1 - 6.7e-59 200.0 0.0 1.2e-58 199.2 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KEZ40358.1 - 1.1e-30 106.9 0.0 2.4e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KEZ40358.1 - 2.4e-15 56.1 0.1 5.3e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ40358.1 - 3.9e-07 30.0 0.2 0.00078 19.2 0.2 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ40358.1 - 1.3e-05 25.1 1.0 0.5 10.1 0.0 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KEZ40358.1 - 0.0016 18.1 0.0 0.0054 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KEZ40358.1 - 0.1 12.3 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ceramidase_alk PF04734.13 KEZ40359.1 - 8.3e-217 720.8 0.0 9.7e-217 720.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KEZ40359.1 - 2.9e-58 196.4 0.1 4.9e-58 195.7 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal zf-RING_4 PF14570.6 KEZ40361.1 - 1e-19 70.0 12.0 1.7e-19 69.3 12.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 KEZ40361.1 - 1.1e-08 34.8 0.0 4.6e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 KEZ40361.1 - 1.9e-07 30.8 7.1 3.4e-07 30.0 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KEZ40361.1 - 0.00016 21.2 4.0 0.00016 21.2 4.0 3.9 3 1 0 3 3 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KEZ40361.1 - 0.00021 21.5 10.1 0.00045 20.5 10.1 1.6 1 0 0 1 1 1 1 Ring finger domain SET_assoc PF11767.8 KEZ40361.1 - 0.0038 16.8 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 KEZ40361.1 - 0.005 16.7 9.2 0.16 11.8 9.3 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KEZ40361.1 - 0.072 13.0 4.8 0.13 12.2 4.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 KEZ40361.1 - 0.081 13.1 4.1 0.18 12.0 4.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Nup35_RRM_2 PF14605.6 KEZ40361.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-RING_5 PF14634.6 KEZ40361.1 - 0.29 11.1 10.1 0.5 10.4 10.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-UDP PF14569.6 KEZ40361.1 - 0.34 11.1 4.3 0.72 10.0 4.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 KEZ40361.1 - 0.5 10.3 10.2 0.96 9.4 10.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ40361.1 - 1.6 8.7 9.9 3.1 7.7 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.19 KEZ40362.1 - 1.5e-45 154.8 0.0 2.1e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HECT PF00632.25 KEZ40363.1 - 2e-74 250.9 0.0 2.8e-73 247.1 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KEZ40363.1 - 0.00012 22.0 9.2 4.3 7.5 0.0 6.6 6 1 1 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KEZ40363.1 - 0.023 14.9 1.1 17 6.0 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat CLASP_N PF12348.8 KEZ40363.1 - 0.029 14.0 0.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.6 KEZ40363.1 - 0.031 14.8 0.2 6.1 7.5 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat BUD22 PF09073.10 KEZ40363.1 - 8.5 5.6 48.5 0.018 14.4 9.6 3.4 3 0 0 3 3 3 0 BUD22 E1_dh PF00676.20 KEZ40364.1 - 1.9e-89 299.6 0.0 2.3e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KEZ40364.1 - 0.00054 19.8 0.1 0.01 15.6 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SGS PF05002.15 KEZ40364.1 - 0.035 14.2 0.8 0.1 12.7 0.2 1.9 2 0 0 2 2 2 0 SGS domain DXP_synthase_N PF13292.6 KEZ40364.1 - 0.082 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Ubie_methyltran PF01209.18 KEZ40365.1 - 3.2e-75 252.5 0.0 3.8e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KEZ40365.1 - 8.4e-17 61.7 0.0 3.6e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40365.1 - 1.1e-14 54.9 0.0 5.2e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40365.1 - 7.8e-13 48.5 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ40365.1 - 1.9e-10 41.3 0.0 3.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ40365.1 - 4e-06 26.8 0.0 5.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KEZ40365.1 - 0.0095 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase DUF1682 PF07946.14 KEZ40365.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2433 PF10360.9 KEZ40366.1 - 6.1e-50 168.5 0.0 9.6e-50 167.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KEZ40366.1 - 0.00056 20.5 0.0 0.0011 19.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ40366.1 - 0.0032 17.7 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 KEZ40366.1 - 0.32 11.0 6.6 0.47 10.4 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRCC PF10253.9 KEZ40366.1 - 4.6 8.0 16.4 2.2 9.1 14.0 1.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CCDC53 PF10152.9 KEZ40366.1 - 8.3 6.8 12.9 2.8e+02 1.9 12.5 2.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Zds_C PF08632.10 KEZ40367.1 - 5.4e-28 96.5 1.3 5.4e-28 96.5 1.3 1.8 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pro_isomerase PF00160.21 KEZ40368.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2905 PF11146.8 KEZ40368.1 - 3.3 7.9 7.0 8.2 6.7 0.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) Zn_clus PF00172.18 KEZ40369.1 - 2.1e-07 31.0 8.2 5.2e-07 29.7 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_GDSL_2 PF13472.6 KEZ40370.1 - 1.3e-14 55.0 0.3 2.3e-14 54.2 0.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ40370.1 - 9.2e-07 29.0 0.1 1.2e-05 25.4 0.1 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4051 PF13260.6 KEZ40372.1 - 0.032 13.9 2.0 0.21 11.4 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF2721 PF11026.8 KEZ40372.1 - 1.7 8.5 7.6 0.1 12.5 1.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) RuBisCO_large PF00016.20 KEZ40373.1 - 0.015 14.5 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Fig1 PF12351.8 KEZ40374.1 - 2.1e-36 125.6 8.2 2.4e-36 125.4 8.2 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 Peptidase_C74 PF12387.8 KEZ40374.1 - 0.016 14.7 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Oxidored_q2 PF00420.24 KEZ40374.1 - 0.038 13.6 0.0 0.038 13.6 0.0 2.6 2 2 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L OppC_N PF12911.7 KEZ40374.1 - 2.6 8.1 0.0 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Col_cuticle_N PF01484.17 KEZ40374.1 - 3.8 7.7 0.0 3.8 7.7 0.0 3.4 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Ank_2 PF12796.7 KEZ40375.1 - 7e-31 106.7 0.0 1.6e-13 51.1 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ40375.1 - 5.8e-28 96.9 0.1 7.2e-11 42.4 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ40375.1 - 4.7e-25 84.9 0.9 3.8e-05 23.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KEZ40375.1 - 7.1e-23 80.0 7.3 4.9e-05 23.6 0.0 6.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KEZ40375.1 - 2.9e-20 72.0 2.3 9.8e-07 28.9 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.18 KEZ40375.1 - 9.7e-10 38.2 2.1 2e-09 37.2 2.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF585 PF04522.12 KEZ40375.1 - 0.0051 16.5 0.1 0.0094 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF585) Phage_T7_Capsid PF05396.11 KEZ40375.1 - 0.056 13.8 0.5 2 8.8 0.0 3.4 3 1 1 4 4 4 0 Phage T7 capsid assembly protein MID_MedPIWI PF18296.1 KEZ40375.1 - 0.1 12.4 5.2 0.64 9.8 1.5 2.4 2 0 0 2 2 2 0 MID domain of medPIWI EMP70 PF02990.16 KEZ40375.1 - 0.17 10.5 1.2 0.28 9.8 1.2 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 KGG PF10685.9 KEZ40376.1 - 2.9e-24 84.6 11.0 4.1e-10 39.6 0.4 3.3 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif CFEM PF05730.11 KEZ40377.1 - 2.9e-05 24.1 9.2 3.8e-05 23.7 9.2 1.3 1 0 0 1 1 1 1 CFEM domain adh_short_C2 PF13561.6 KEZ40378.1 - 9.5e-52 175.9 0.0 1.2e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ40378.1 - 4.2e-46 156.9 0.0 5.3e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ40378.1 - 3.4e-08 33.6 0.0 5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF2974 PF11187.8 KEZ40378.1 - 0.067 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1776 PF08643.10 KEZ40378.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KEZ40378.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RCC1 PF00415.18 KEZ40379.1 - 1.2e-55 185.9 23.6 8.5e-09 35.9 0.0 8.6 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEZ40379.1 - 2.7e-31 106.7 33.7 9.7e-07 28.4 1.1 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 KEZ40379.1 - 0.19 11.8 3.6 1.5 8.9 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Macoilin PF09726.9 KEZ40379.1 - 0.67 8.4 6.9 0.84 8.1 6.9 1.1 1 0 0 1 1 1 0 Macoilin family Egh16-like PF11327.8 KEZ40380.1 - 2.6e-69 233.3 8.8 3.2e-69 233.0 8.8 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Methyltransf_23 PF13489.6 KEZ40381.1 - 2e-22 79.8 0.0 2.9e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40381.1 - 1.6e-12 48.0 0.0 5.8e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40381.1 - 6.1e-10 39.6 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40381.1 - 8.1e-10 38.7 0.0 1.6e-08 34.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ40381.1 - 5.1e-08 33.6 0.0 1.9e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEZ40381.1 - 7.5e-05 22.2 0.0 0.00017 21.0 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KEZ40381.1 - 0.0021 17.5 0.0 0.0051 16.3 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KEZ40381.1 - 0.003 17.7 0.0 0.0051 17.0 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ40381.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 KEZ40381.1 - 0.11 12.3 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase Asp PF00026.23 KEZ40383.1 - 3.8e-38 131.7 0.2 4.9e-38 131.3 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ40383.1 - 1.4e-05 25.4 0.1 0.00028 21.2 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MFS_1 PF07690.16 KEZ40385.1 - 2.6e-28 99.0 51.0 5.2e-28 98.0 51.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ40385.1 - 9.7e-11 41.2 6.0 9.7e-11 41.2 6.0 3.3 1 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KEZ40385.1 - 1.3e-08 33.8 17.2 1.5e-08 33.6 4.8 2.3 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1479 PF07350.12 KEZ40387.1 - 3.7e-117 391.6 0.1 2.2e-95 319.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 KEZ40387.1 - 0.059 13.6 0.1 14 5.9 0.0 2.5 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) AAA_22 PF13401.6 KEZ40388.1 - 0.0003 21.1 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KEZ40388.1 - 0.00039 20.6 0.5 0.24 11.4 0.1 3.0 4 0 0 4 4 4 2 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KEZ40388.1 - 0.00087 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KEZ40388.1 - 0.0012 19.2 0.3 0.53 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KEZ40388.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Zot PF05707.12 KEZ40388.1 - 0.16 11.6 0.0 0.51 10.0 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.9 KEZ40388.1 - 0.16 10.8 0.0 0.47 9.3 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Fungal_trans PF04082.18 KEZ40389.1 - 0.00018 20.6 0.1 0.0003 19.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KEZ40393.1 - 7.4e-48 163.4 0.0 9.6e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EPTP PF03736.17 KEZ40393.1 - 0.076 13.0 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 EPTP domain FMO-like PF00743.19 KEZ40394.1 - 1.3e-11 43.6 0.5 1.7e-10 40.0 0.5 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ40394.1 - 2.8e-09 37.0 0.0 3.6e-08 33.5 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ40394.1 - 3.1e-09 36.5 0.0 9.2e-05 21.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ40394.1 - 9.8e-09 35.2 0.0 0.00019 21.1 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KEZ40394.1 - 7.4e-07 28.6 0.5 0.00051 19.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ40394.1 - 1.6e-06 27.6 0.0 0.00085 18.7 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ40394.1 - 0.0016 18.4 0.0 0.19 11.7 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEZ40394.1 - 0.14 12.7 1.1 1.6 9.3 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40394.1 - 0.25 10.0 1.1 0.62 8.7 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.25 KEZ40395.1 - 3.6e-32 111.4 0.0 4.3e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ40395.1 - 1.3e-30 106.7 0.1 1.5e-30 106.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEZ40395.1 - 0.0043 16.5 0.0 0.012 15.1 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ40395.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Abhydrolase_3 PF07859.13 KEZ40396.1 - 3.4e-50 170.8 0.0 4e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEZ40396.1 - 1.6e-07 30.6 0.0 4.4e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 KEZ40396.1 - 0.0007 18.6 0.0 0.0009 18.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KEZ40396.1 - 0.00071 20.2 0.5 0.0014 19.3 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ40396.1 - 0.001 18.8 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ40396.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ceramidase PF05875.12 KEZ40397.1 - 7.2e-62 209.2 0.3 8.4e-62 209.0 0.3 1.0 1 0 0 1 1 1 1 Ceramidase MFS_1 PF07690.16 KEZ40398.1 - 1.3e-35 123.0 39.7 2e-35 122.4 39.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.7 KEZ40398.1 - 0.00024 21.0 0.2 0.00047 20.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 KEZ40398.1 - 0.0038 16.8 0.1 0.0073 15.9 0.1 1.4 1 0 0 1 1 1 1 F-box DUF3760 PF12586.8 KEZ40398.1 - 0.022 14.9 0.2 0.079 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) SVM_signal PF12113.8 KEZ40398.1 - 0.2 11.6 0.7 0.54 10.2 0.7 1.7 1 0 0 1 1 1 0 SVM protein signal sequence Metallopep PF12044.8 KEZ40399.1 - 6.9e-128 426.9 0.0 9e-128 426.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 KEZ40399.1 - 0.007 16.9 0.2 0.027 15.0 0.2 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KEZ40399.1 - 0.055 13.6 0.2 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12 ZZ PF00569.17 KEZ40399.1 - 2 8.3 14.7 0.37 10.7 10.7 1.9 1 1 0 1 1 1 0 Zinc finger, ZZ type Cellulase PF00150.18 KEZ40400.1 - 5.4e-08 32.6 0.2 1.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AF-4 PF05110.13 KEZ40400.1 - 1.2 7.1 4.5 1.7 6.6 4.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Serglycin PF04360.12 KEZ40400.1 - 9.1 6.2 11.1 20 5.1 11.1 1.5 1 0 0 1 1 1 0 Serglycin Fungal_trans PF04082.18 KEZ40401.1 - 8.7e-17 61.0 0.8 1.9e-16 59.9 0.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40401.1 - 0.017 15.2 2.0 0.028 14.5 2.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KEZ40402.1 - 1.2e-78 263.4 48.1 1.5e-42 145.4 23.4 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ40402.1 - 2.4e-35 122.0 0.0 3.2e-17 63.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEZ40402.1 - 5.2e-30 103.2 12.2 1.5e-27 95.3 0.0 4.0 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KEZ40402.1 - 4.5e-13 49.6 0.1 3e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KEZ40402.1 - 3.4e-07 29.7 40.6 1.7e-06 27.4 10.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KEZ40402.1 - 4.6e-07 30.4 0.1 0.0099 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ40402.1 - 1e-05 25.5 0.0 0.00067 19.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KEZ40402.1 - 1.7e-05 24.5 0.1 0.00065 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ40402.1 - 7.1e-05 23.0 0.0 0.021 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ40402.1 - 8.2e-05 22.3 0.4 0.019 14.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KEZ40402.1 - 0.00057 19.8 0.4 0.76 9.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KEZ40402.1 - 0.0014 19.2 0.0 0.021 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KEZ40402.1 - 0.0041 16.6 0.0 0.16 11.4 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KEZ40402.1 - 0.0044 16.8 0.0 0.37 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ40402.1 - 0.0086 16.4 0.1 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KEZ40402.1 - 0.017 14.7 0.8 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEZ40402.1 - 0.043 13.7 3.5 2 8.3 0.1 3.1 4 0 0 4 4 3 0 NACHT domain MMR_HSR1 PF01926.23 KEZ40402.1 - 0.093 12.8 0.1 22 5.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Creb_binding PF09030.10 KEZ40402.1 - 0.15 12.8 0.0 0.54 11.0 0.0 1.9 1 0 0 1 1 1 0 Creb binding PilM_2 PF11104.8 KEZ40402.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PDR_assoc PF08370.11 KEZ40402.1 - 0.32 10.8 11.3 2.9 7.7 0.7 4.0 3 0 0 3 3 3 0 Plant PDR ABC transporter associated p450 PF00067.22 KEZ40403.1 - 3.7e-38 131.5 0.0 4.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 KEZ40405.1 - 7.6e-21 75.1 0.0 8e-10 39.0 0.0 2.8 2 0 0 2 2 2 2 Phosphotransferase enzyme family Epimerase PF01370.21 KEZ40405.1 - 7e-18 65.0 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ40405.1 - 1.7e-11 43.7 0.0 2.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEZ40405.1 - 2.8e-10 39.8 0.0 8.5e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KEZ40405.1 - 5.2e-08 32.7 0.0 8.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KEZ40405.1 - 1.5e-06 28.2 0.1 2.9e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KEZ40405.1 - 0.0017 17.8 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ40405.1 - 0.0038 17.1 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Haspin_kinase PF12330.8 KEZ40405.1 - 0.01 14.8 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain HCBP_related PF06594.11 KEZ40405.1 - 0.91 9.5 4.0 3.3 7.7 0.0 3.1 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain Alpha-L-AF_C PF06964.12 KEZ40406.1 - 3.9e-19 69.4 0.0 6.6e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Gtr1_RagA PF04670.12 KEZ40407.1 - 9.2e-93 309.9 0.0 1.1e-92 309.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KEZ40407.1 - 8.1e-08 32.5 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEZ40407.1 - 3e-07 30.2 0.0 7.5e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KEZ40407.1 - 3.2e-07 30.4 0.0 5.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KEZ40407.1 - 6.5e-06 25.7 0.0 9.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 KEZ40407.1 - 0.0049 17.4 0.1 0.011 16.3 0.1 1.6 1 0 0 1 1 1 1 ABC transporter G-alpha PF00503.20 KEZ40407.1 - 0.008 15.4 2.7 1.1 8.4 0.4 2.8 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 KEZ40407.1 - 0.013 15.2 1.5 0.069 12.9 0.4 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 KEZ40407.1 - 0.021 14.0 0.1 0.048 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KEZ40407.1 - 0.039 14.1 0.2 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 KEZ40407.1 - 0.06 13.2 0.3 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KEZ40407.1 - 0.11 12.0 0.1 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region SEP PF08059.13 KEZ40408.1 - 3.7e-19 69.0 0.0 8.1e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 KEZ40408.1 - 1.1e-11 44.3 0.2 1.8e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KEZ40408.1 - 7.9e-08 32.4 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 KEZ40408.1 - 0.042 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 TAP C-terminal domain UBA PF00627.31 KEZ40408.1 - 0.11 12.4 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 UBA/TS-N domain MRPL52 PF18699.1 KEZ40408.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Mitoribosomal protein mL52 TOM13 PF08219.11 KEZ40409.1 - 2.3e-34 117.2 0.0 3.6e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KEZ40410.1 - 1e-14 54.8 1.1 1e-14 54.8 1.1 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein DUF1688 PF07958.11 KEZ40411.1 - 2.9e-175 583.0 0.0 3.3e-175 582.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DEAD PF00270.29 KEZ40413.1 - 2.6e-42 144.6 0.1 4.3e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40413.1 - 1.4e-33 115.5 0.0 5e-33 113.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KEZ40413.1 - 0.00041 20.1 0.1 0.00061 19.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ40413.1 - 0.00067 20.0 0.1 0.013 15.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KEZ40413.1 - 0.0022 18.0 0.0 0.0042 17.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KEZ40413.1 - 0.061 13.3 0.3 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 KEZ40413.1 - 0.073 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KEZ40413.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 KEZ40413.1 - 0.17 12.1 1.1 0.83 9.9 1.1 2.0 1 1 0 1 1 1 0 AAA domain DUF5393 PF17371.2 KEZ40413.1 - 0.17 9.9 0.1 0.24 9.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5393) PLU-1 PF08429.11 KEZ40414.1 - 3.6e-112 374.9 11.8 3.3e-109 365.2 12.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KEZ40414.1 - 4.2e-43 146.4 0.1 1.1e-42 145.1 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KEZ40414.1 - 1.6e-21 76.7 0.0 5.7e-21 75.0 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KEZ40414.1 - 1e-16 60.6 2.3 2.6e-16 59.3 2.3 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KEZ40414.1 - 1.4e-15 56.9 30.2 4.1e-08 33.0 7.5 3.8 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 KEZ40414.1 - 1.6e-13 50.8 5.2 4.5e-13 49.4 5.2 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_4 PF16866.5 KEZ40414.1 - 5.3e-05 23.2 22.2 0.00025 21.1 5.8 3.0 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KEZ40414.1 - 0.066 13.1 19.6 0.026 14.4 3.0 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.15 KEZ40414.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.3 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger PHD_2 PF13831.6 KEZ40414.1 - 3.3 7.3 11.3 1 9.0 1.6 2.9 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 KEZ40414.1 - 7.4 6.2 15.1 0.32 10.6 1.9 3.0 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Sdh_cyt PF01127.22 KEZ40415.1 - 1.5e-19 70.2 3.9 1.9e-19 69.9 3.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 KEZ40416.1 - 7.6e-24 83.9 0.0 1.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KEZ40416.1 - 8.6e-21 73.9 0.2 1.9e-20 72.8 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KEZ40416.1 - 0.0083 16.5 0.2 0.016 15.6 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEZ40416.1 - 0.048 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DJ-1_PfpI PF01965.24 KEZ40417.1 - 3e-16 59.7 0.0 5.3e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KEZ40417.1 - 1.8e-08 34.3 0.0 5.4e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 KEZ40417.1 - 0.00079 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 KEZ40417.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KEZ40417.1 - 0.05 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I SRP54 PF00448.22 KEZ40418.1 - 3.4e-77 258.5 2.4 9.1e-77 257.1 1.3 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KEZ40418.1 - 3e-31 108.0 3.7 3e-31 108.0 3.7 3.8 2 1 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KEZ40418.1 - 2.7e-19 69.1 0.5 7.3e-19 67.8 0.5 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KEZ40418.1 - 1.5e-06 27.9 0.3 6.5e-06 25.9 0.3 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEZ40418.1 - 3.1e-06 27.4 0.1 9.5e-06 25.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KEZ40418.1 - 2.9e-05 24.5 0.0 6.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KEZ40418.1 - 0.00041 20.8 1.2 0.00096 19.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KEZ40418.1 - 0.00063 19.5 0.4 0.0044 16.7 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase CbiA PF01656.23 KEZ40418.1 - 0.00071 19.6 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KEZ40418.1 - 0.00092 19.1 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.10 KEZ40418.1 - 0.0011 18.4 0.8 2.5 7.5 0.1 3.3 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit ResIII PF04851.15 KEZ40418.1 - 0.0019 18.2 0.4 0.0077 16.3 0.4 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit 6PF2K PF01591.18 KEZ40418.1 - 0.0022 17.3 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_30 PF13604.6 KEZ40418.1 - 0.0027 17.4 2.1 0.003 17.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KEZ40418.1 - 0.0031 16.8 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KEZ40418.1 - 0.0034 16.4 0.5 0.0034 16.4 0.5 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KEZ40418.1 - 0.0049 16.9 0.2 0.11 12.6 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KEZ40418.1 - 0.0097 15.7 0.1 0.034 13.9 0.1 2.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MobB PF03205.14 KEZ40418.1 - 0.01 15.7 0.2 0.035 14.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KEZ40418.1 - 0.012 15.9 0.0 0.047 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ40418.1 - 0.019 15.2 0.1 0.037 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ40418.1 - 0.033 14.7 0.1 0.1 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KEZ40418.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEZ40418.1 - 0.1 12.5 1.4 1.5 8.7 1.4 2.3 1 1 0 1 1 1 0 NTPase Arf PF00025.21 KEZ40418.1 - 0.13 11.7 0.0 0.42 10.0 0.0 1.9 1 0 0 1 1 1 0 ADP-ribosylation factor family SGL PF08450.12 KEZ40419.1 - 3.9e-05 23.4 0.7 0.00076 19.1 0.0 2.8 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KEZ40419.1 - 0.00052 19.9 0.1 0.88 9.6 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Lactonase PF10282.9 KEZ40419.1 - 0.0023 17.2 0.0 1 8.5 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Phytase-like PF13449.6 KEZ40419.1 - 0.094 12.6 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Esterase-like activity of phytase FlaE PF07559.14 KEZ40419.1 - 0.14 12.7 0.5 46 4.6 0.0 3.2 1 1 1 2 2 2 0 Flagellar basal body protein FlaE Calc_CGRP_IAPP PF00214.19 KEZ40420.1 - 0.045 14.1 0.0 0.082 13.3 0.0 1.4 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family His_Phos_2 PF00328.22 KEZ40420.1 - 0.05 12.9 0.0 0.99 8.7 0.0 2.1 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) HCV_NS5a_1b PF08301.13 KEZ40420.1 - 0.11 13.1 0.2 5.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b MFS_1 PF07690.16 KEZ40422.1 - 1.7e-36 125.9 25.0 1.7e-36 125.9 25.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KEZ40423.1 - 3.4e-21 75.5 0.8 1.2e-20 73.7 0.8 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KEZ40424.1 - 2.4e-51 175.0 0.0 3.8e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KEZ40424.1 - 1.6e-07 31.0 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40424.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEZ40424.1 - 0.095 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KEZ40424.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FAD_binding_4 PF01565.23 KEZ40425.1 - 6.7e-23 81.0 0.9 1.1e-22 80.3 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ40425.1 - 3.2e-07 30.3 0.2 7e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 KEZ40426.1 - 3.4e-18 66.4 0.0 6.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KEZ40428.1 - 3e-52 177.3 0.0 4.6e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEZ40428.1 - 9.5e-08 32.1 5.8 0.0032 17.8 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type CENP-L PF13092.6 KEZ40428.1 - 0.16 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 EPL1 PF10513.9 KEZ40428.1 - 3.4 8.0 8.1 1.6 9.1 3.7 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Ank_2 PF12796.7 KEZ40429.1 - 1.7e-16 60.6 3.4 1.7e-13 50.9 0.9 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ40429.1 - 1.3e-13 51.2 0.0 2.1e-10 40.9 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ40429.1 - 6.7e-11 42.2 0.8 1.8e-06 28.1 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ40429.1 - 1.7e-09 37.1 0.2 0.0013 19.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KEZ40429.1 - 2.2e-09 37.3 0.7 0.00036 20.9 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat SQHop_cyclase_C PF13243.6 KEZ40430.1 - 7.8e-49 166.5 3.6 2.5e-47 161.6 1.9 2.7 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KEZ40430.1 - 5.2e-40 137.4 7.3 3.6e-34 118.2 1.3 3.6 4 1 0 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KEZ40430.1 - 7.4e-28 96.0 16.1 1.7e-10 40.4 0.3 6.0 6 1 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KEZ40430.1 - 0.0016 17.8 0.3 2.8 7.2 0.0 3.8 3 1 1 4 4 4 2 Pectic acid lyase TED_complement PF07678.14 KEZ40430.1 - 0.0024 17.0 0.1 0.11 11.4 0.1 3.0 2 1 1 3 3 3 1 A-macroglobulin TED domain Chromadorea_ALT PF05535.12 KEZ40430.1 - 0.0096 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 Chromadorea ALT protein TauD PF02668.16 KEZ40431.1 - 5.5e-38 131.3 0.1 1e-37 130.4 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SGS PF05002.15 KEZ40431.1 - 4.5e-29 100.4 3.4 1e-28 99.3 3.4 1.7 1 0 0 1 1 1 1 SGS domain DUF971 PF06155.12 KEZ40431.1 - 1.9e-05 25.2 0.0 9.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 KEZ40431.1 - 0.01 15.0 0.0 0.043 12.9 0.0 1.9 1 1 0 1 1 1 0 CsiD CS PF04969.16 KEZ40431.1 - 0.062 14.3 0.1 0.13 13.3 0.1 1.6 1 0 0 1 1 1 0 CS domain TPR_2 PF07719.17 KEZ40431.1 - 0.066 13.4 0.3 0.89 9.8 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4719 PF15843.5 KEZ40431.1 - 1.3 9.1 3.8 10 6.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) TPR_16 PF13432.6 KEZ40431.1 - 8.4 7.1 14.7 8.3 7.2 3.4 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Glyco_transf_21 PF13506.6 KEZ40432.1 - 4.7e-13 49.0 0.0 1.9e-05 24.2 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KEZ40432.1 - 3.5e-07 30.4 0.0 2.5e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ40432.1 - 3.3e-05 23.8 0.0 0.00045 20.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 MFS_1 PF07690.16 KEZ40433.1 - 1.9e-35 122.5 25.0 1.9e-26 92.8 10.2 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.13 KEZ40433.1 - 6.2e-05 21.6 2.2 6.7e-05 21.5 0.1 1.7 1 1 0 2 2 2 1 Transmembrane secretion effector BT1 PF03092.16 KEZ40433.1 - 0.0032 15.7 0.0 0.15 10.2 0.0 2.7 2 0 0 2 2 2 2 BT1 family Dioxygenase_C PF00775.21 KEZ40434.1 - 5.9e-06 25.8 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase DUF3328 PF11807.8 KEZ40435.1 - 2e-18 67.0 4.3 2.6e-18 66.6 4.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CBM_1 PF00734.18 KEZ40436.1 - 1.1e-08 34.9 6.2 1.7e-08 34.3 6.2 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain AMP-binding PF00501.28 KEZ40437.1 - 1.4e-59 201.8 0.0 2.1e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KEZ40437.1 - 1e-09 38.6 0.0 3.1e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 KEZ40437.1 - 4e-08 32.7 12.3 0.00016 21.3 0.1 6.0 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ40437.1 - 0.001 18.8 19.2 0.19 11.5 0.8 6.1 5 2 1 6 6 6 3 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.6 KEZ40437.1 - 0.013 16.5 0.0 8.7 7.4 0.0 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Nop10p PF04135.12 KEZ40438.1 - 4.9e-21 74.5 0.1 6e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CRAL_TRIO PF00650.20 KEZ40439.1 - 1e-41 142.3 0.0 1.6e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEZ40439.1 - 6.6e-14 51.8 1.3 6.6e-14 51.8 1.3 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KEZ40439.1 - 0.00025 21.2 0.0 0.00039 20.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TRAPP PF04051.16 KEZ40440.1 - 8.8e-41 139.0 0.0 1e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.11 KEZ40441.1 - 3.7e-35 120.0 0.4 4.2e-35 119.8 0.4 1.0 1 0 0 1 1 1 1 Apc13p protein ABC_membrane PF00664.23 KEZ40442.1 - 1.4e-52 179.0 32.6 7.5e-33 114.3 10.5 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ40442.1 - 6.4e-51 172.5 0.0 3.6e-30 105.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ40442.1 - 3.8e-08 33.0 2.5 0.0059 16.1 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEZ40442.1 - 2.5e-06 28.1 4.7 0.0032 18.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KEZ40442.1 - 9.8e-06 25.2 0.1 0.097 12.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEZ40442.1 - 3.7e-05 23.8 0.0 0.089 12.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ40442.1 - 4.5e-05 23.4 0.0 0.096 12.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEZ40442.1 - 0.00033 21.1 1.0 0.33 11.3 0.1 2.9 2 2 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KEZ40442.1 - 0.00054 19.1 0.0 0.2 10.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 KEZ40442.1 - 0.0033 17.7 1.3 7.9 6.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 KEZ40442.1 - 0.0049 16.2 0.2 1.6 8.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 KEZ40442.1 - 0.0056 16.5 0.1 13 5.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KEZ40442.1 - 0.0065 16.6 5.3 0.033 14.3 0.0 2.9 3 0 0 3 3 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 KEZ40442.1 - 0.0096 15.7 0.0 0.6 9.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 KEZ40442.1 - 0.019 14.1 0.2 0.66 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KEZ40442.1 - 0.02 14.6 0.9 6.3 6.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KEZ40442.1 - 0.029 14.4 0.4 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.9 KEZ40442.1 - 0.037 12.9 0.5 1.3 7.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 KEZ40442.1 - 0.046 13.4 0.1 1 9.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KEZ40442.1 - 0.046 13.2 0.0 9.5 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_10 PF12846.7 KEZ40442.1 - 0.049 12.6 0.1 8.2 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.6 KEZ40442.1 - 0.059 12.9 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEZ40442.1 - 0.07 13.5 0.2 56 4.2 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KEZ40442.1 - 0.1 12.6 0.0 6.5 6.7 0.0 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KEZ40442.1 - 0.1 12.3 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 KEZ40442.1 - 0.14 11.3 1.2 12 5.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_27 PF13514.6 KEZ40442.1 - 0.16 11.6 0.2 1.7 8.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain SecY PF00344.20 KEZ40443.1 - 1.4e-70 238.0 8.7 1.8e-70 237.6 8.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KEZ40443.1 - 2.6e-17 62.4 0.2 1e-16 60.5 0.2 2.1 1 0 0 1 1 1 1 Plug domain of Sec61p Fungal_trans PF04082.18 KEZ40444.1 - 7.1e-21 74.4 0.1 1e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40444.1 - 6.9e-09 35.7 8.6 1.2e-08 34.9 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 KEZ40444.1 - 2.9 7.0 6.9 4.1 6.5 6.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 KEZ40445.1 - 9.6e-45 153.0 49.1 1.2e-41 142.8 50.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ40445.1 - 3.9e-15 55.3 23.8 7.8e-15 54.3 23.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EphA2_TM PF14575.6 KEZ40445.1 - 4.8 8.1 5.8 11 7.0 0.0 3.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 KEZ40446.1 - 1.3e-10 41.1 0.0 1.9e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40446.1 - 2.9e-07 30.1 0.0 4.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ40446.1 - 0.078 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NUDIX PF00293.28 KEZ40447.1 - 1.3e-18 67.3 0.1 1.7e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Y_phosphatase3 PF13350.6 KEZ40448.1 - 1.6e-50 172.3 0.0 1.8e-50 172.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEZ40448.1 - 5.8e-05 22.8 0.0 8.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KEZ40448.1 - 0.0056 16.3 0.0 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 KEZ40448.1 - 0.029 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 KEZ40448.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Adaptin_binding PF10199.9 KEZ40449.1 - 6.5e-12 46.1 8.5 9.4e-12 45.6 8.5 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Wbp11 PF09429.10 KEZ40449.1 - 0.12 12.8 2.6 0.26 11.7 2.6 1.6 1 0 0 1 1 1 0 WW domain binding protein 11 Homeodomain PF00046.29 KEZ40450.1 - 8.1e-19 67.2 3.4 1.6e-18 66.3 3.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KEZ40450.1 - 0.00023 21.0 0.3 0.00052 19.9 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain PhoLip_ATPase_C PF16212.5 KEZ40451.1 - 3.9e-71 239.7 25.2 3.9e-71 239.7 25.2 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEZ40451.1 - 6.8e-26 89.8 1.4 7.7e-23 80.0 0.1 2.8 2 0 0 2 2 2 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEZ40451.1 - 1.1e-12 48.7 0.1 0.00014 22.2 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEZ40451.1 - 9.9e-12 44.7 0.0 2.7e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KEZ40451.1 - 1.8e-11 43.9 0.0 1.9e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEZ40451.1 - 0.0049 16.6 0.5 0.018 14.8 0.0 2.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KEZ40451.1 - 0.19 11.9 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ETRAMP PF09716.10 KEZ40451.1 - 0.25 11.4 0.7 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) HlyIII PF03006.20 KEZ40452.1 - 4.5e-33 114.8 10.5 6.1e-33 114.4 10.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_M50B PF13398.6 KEZ40453.1 - 1.1e-60 204.7 19.2 1.4e-60 204.4 19.2 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 KEZ40453.1 - 0.0053 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M41 PF01434.18 KEZ40453.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 DUF4191 PF13829.6 KEZ40453.1 - 3 7.1 10.6 1 8.7 3.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) TIP120 PF08623.10 KEZ40454.1 - 1.7e-70 236.2 0.1 4.4e-67 225.1 0.0 4.3 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KEZ40454.1 - 5e-17 62.1 28.4 0.013 15.9 0.3 8.8 6 3 1 8 8 8 4 HEAT repeats HEAT PF02985.22 KEZ40454.1 - 2.1e-09 36.8 33.8 0.079 13.3 0.1 11.7 14 0 0 14 14 11 4 HEAT repeat Cnd1 PF12717.7 KEZ40454.1 - 8.9e-07 29.1 14.4 0.0084 16.2 0.6 6.3 7 1 1 8 8 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KEZ40454.1 - 1.2e-06 27.4 5.8 0.00051 18.7 0.0 5.9 3 2 2 6 6 6 1 Adaptin N terminal region CLASP_N PF12348.8 KEZ40454.1 - 7.4e-06 25.7 5.1 0.034 13.7 0.0 5.2 5 1 1 6 6 6 1 CLASP N terminal RTP1_C1 PF10363.9 KEZ40454.1 - 1.1e-05 25.6 10.1 5 7.3 0.1 6.7 7 1 1 8 8 7 3 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 KEZ40454.1 - 1.5e-05 25.5 0.3 9.8 6.9 0.0 6.0 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KEZ40454.1 - 0.00013 22.4 28.7 1 10.0 0.5 11.7 12 1 1 13 13 11 1 HEAT-like repeat MMS19_N PF14500.6 KEZ40454.1 - 0.0016 18.1 6.5 0.85 9.1 0.6 4.5 3 1 1 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II MOR2-PAG1_N PF14222.6 KEZ40454.1 - 0.1 11.6 0.1 2.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Cell morphogenesis N-terminal RICTOR_N PF14664.6 KEZ40454.1 - 0.11 11.5 2.1 6 5.7 0.1 3.6 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KEZ40454.1 - 0.11 12.9 0.5 7.6 7.0 0.0 3.8 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain IFRD PF05004.13 KEZ40454.1 - 0.12 11.5 15.9 3.1 6.8 1.4 5.3 5 2 0 5 5 5 0 Interferon-related developmental regulator (IFRD) CENP-B_dimeris PF09026.10 KEZ40454.1 - 0.22 11.9 13.9 0.55 10.7 13.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Proteasom_PSMB PF10508.9 KEZ40454.1 - 0.24 9.8 1.3 6.7 5.1 0.0 3.2 3 1 1 4 4 4 0 Proteasome non-ATPase 26S subunit DNA_pol_phi PF04931.13 KEZ40454.1 - 0.27 9.3 24.2 1.1 7.3 0.2 3.9 4 0 0 4 4 4 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 KEZ40454.1 - 1.8 8.8 12.5 3.1 8.0 12.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KEZ40454.1 - 2.2 6.4 6.6 1.3 7.2 4.3 1.7 2 0 0 2 2 2 0 Nop14-like family Ribosomal_60s PF00428.19 KEZ40454.1 - 3.6 8.3 5.5 21 5.8 5.5 2.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sigma70_ner PF04546.13 KEZ40454.1 - 3.7 7.4 6.3 4 7.3 4.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region MMS19_C PF12460.8 KEZ40454.1 - 5.2 6.1 8.1 7.1 5.6 0.1 4.5 4 2 0 4 4 4 0 RNAPII transcription regulator C-terminal Astro_capsid_p PF12226.8 KEZ40454.1 - 5.3 6.1 7.9 10 5.2 7.9 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NOA36 PF06524.12 KEZ40454.1 - 5.7 6.2 12.4 8.9 5.5 12.4 1.2 1 0 0 1 1 1 0 NOA36 protein COMPASS-Shg1 PF05205.12 KEZ40455.1 - 7.6e-25 87.6 0.3 1.8e-24 86.4 0.3 1.7 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF-2B PF01008.17 KEZ40457.1 - 9.7e-52 175.9 1.7 3.6e-51 174.0 1.7 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family PLDc_2 PF13091.6 KEZ40457.1 - 0.0028 17.5 0.1 0.0093 15.9 0.0 1.8 2 0 0 2 2 2 1 PLD-like domain Glycos_transf_2 PF00535.26 KEZ40457.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_S26 PF10502.9 KEZ40458.1 - 7.5e-05 22.5 0.0 0.0068 16.2 0.0 2.7 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KEZ40458.1 - 0.00029 20.7 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Arm PF00514.23 KEZ40459.1 - 7.7e-74 241.7 32.1 6.8e-12 45.0 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEZ40459.1 - 1.6e-18 66.8 13.9 0.00018 21.9 0.2 7.5 6 3 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 KEZ40459.1 - 4.2e-16 59.1 9.3 4.4e-05 23.8 0.1 6.8 5 2 2 7 7 7 5 HEAT repeats HEAT PF02985.22 KEZ40459.1 - 2.3e-14 52.3 16.1 0.09 13.1 0.3 9.0 10 1 1 11 11 10 5 HEAT repeat Adaptin_N PF01602.20 KEZ40459.1 - 3.2e-11 42.5 6.0 1.8e-06 26.8 0.1 2.8 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 KEZ40459.1 - 2.9e-10 40.0 4.9 7.9e-06 25.5 1.8 2.9 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KEZ40459.1 - 1.8e-07 29.7 0.2 2.9e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KEZ40459.1 - 5.7e-07 29.1 0.2 0.0017 17.7 0.8 3.1 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 KEZ40459.1 - 2.3e-05 24.5 4.6 0.099 12.7 0.0 4.8 1 1 4 6 6 6 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KEZ40459.1 - 0.00055 20.0 0.4 10 6.3 0.1 4.4 2 1 5 7 7 7 1 V-ATPase subunit H HEAT_PBS PF03130.16 KEZ40459.1 - 0.0043 17.6 4.1 1.2e+02 3.8 0.0 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Tti2 PF10521.9 KEZ40459.1 - 0.0083 15.7 0.3 1.8 8.0 0.0 2.8 3 0 0 3 3 3 1 Tti2 family IFRD PF05004.13 KEZ40459.1 - 0.0091 15.1 3.0 5.4 6.0 0.2 3.8 2 2 1 3 3 3 2 Interferon-related developmental regulator (IFRD) Atx10homo_assoc PF09759.9 KEZ40459.1 - 0.014 15.4 5.4 3.2 7.8 0.1 4.2 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 KEZ40459.1 - 0.17 11.8 1.5 8.5 6.3 0.1 3.2 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central CBS PF00571.28 KEZ40460.1 - 3.1e-23 82.0 8.5 3.9e-10 40.0 0.7 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.27 KEZ40461.1 - 2.1e-09 37.4 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Rep_fac-A_3 PF08661.11 KEZ40462.1 - 5.2e-15 55.7 0.0 8.2e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Replication factor A protein 3 Cwf_Cwc_15 PF04889.12 KEZ40462.1 - 0.0053 16.5 9.9 0.0076 16.0 9.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 KEZ40462.1 - 0.0077 14.9 9.3 0.0095 14.6 9.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 KEZ40462.1 - 0.089 12.2 12.6 0.13 11.7 12.6 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KEZ40462.1 - 0.15 10.3 9.1 0.22 9.8 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KEZ40462.1 - 0.25 10.7 11.6 0.32 10.3 11.6 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 KEZ40462.1 - 0.45 10.4 11.1 0.74 9.7 11.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 KEZ40462.1 - 1 7.5 16.2 1.3 7.1 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 KEZ40462.1 - 1.1 8.5 13.9 0.05 12.9 6.2 1.9 2 0 0 2 2 2 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 KEZ40462.1 - 1.9 8.7 18.7 1.1 9.5 13.6 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 KEZ40462.1 - 3.2 5.7 21.1 4.3 5.3 21.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Alb1 PF09135.11 KEZ40463.1 - 5.3e-28 98.0 11.4 5.3e-28 98.0 11.4 1.3 1 1 0 1 1 1 1 Alb1 Methyltrans_SAM PF10672.9 KEZ40463.1 - 0.11 11.7 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase F-protein PF00469.20 KEZ40463.1 - 0.11 12.0 2.1 0.15 11.6 2.1 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef bZIP_1 PF00170.21 KEZ40464.1 - 1.9e-13 50.3 0.3 4.8e-13 49.0 0.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEZ40464.1 - 1.1e-07 31.8 0.4 2.8e-07 30.5 0.4 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KEZ40464.1 - 0.0011 19.4 0.5 0.0011 19.4 0.5 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Ribosomal_L4 PF00573.22 KEZ40465.1 - 9.5e-46 155.9 0.0 1.3e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.20 KEZ40466.1 - 1e-06 29.1 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PLDc_2 PF13091.6 KEZ40467.1 - 6.6e-15 55.2 0.0 2.9e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KEZ40467.1 - 2.7e-08 33.7 0.3 0.0067 16.6 0.0 2.9 2 1 0 2 2 2 2 Phospholipase D Active site motif DUF4154 PF13689.6 KEZ40467.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 YfiR/HmsC-like DnaG_DnaB_bind PF08278.11 KEZ40467.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding NDUFA12 PF05071.16 KEZ40468.1 - 6.2e-24 84.7 0.1 7.7e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PNTB PF02233.16 KEZ40469.1 - 4.1e-132 441.4 34.1 8.9e-87 291.9 1.0 3.1 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KEZ40469.1 - 6.8e-74 247.8 0.2 1.6e-73 246.6 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KEZ40469.1 - 4.5e-47 159.8 1.0 1.6e-46 158.0 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KEZ40469.1 - 2e-29 101.8 2.0 2e-29 101.8 2.0 4.0 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 KEZ40469.1 - 0.005 16.8 0.2 0.028 14.4 0.2 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ40469.1 - 0.0071 15.7 0.1 0.54 9.6 0.0 3.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KEZ40469.1 - 0.027 13.7 0.2 0.027 13.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.14 KEZ40469.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) FtsJ PF01728.19 KEZ40469.1 - 0.12 12.5 0.1 36 4.4 0.0 3.2 2 1 1 3 3 3 0 FtsJ-like methyltransferase TPP_enzyme_M PF00205.22 KEZ40469.1 - 0.13 12.0 0.3 0.88 9.3 0.3 2.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain FAD_binding_2 PF00890.24 KEZ40469.1 - 0.14 11.2 4.2 0.59 9.2 1.7 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KEZ40469.1 - 0.58 10.4 4.7 0.18 12.1 0.3 2.6 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Thymidylate_kin PF02223.17 KEZ40470.1 - 1.8e-44 151.7 0.0 5.1e-42 143.6 0.0 2.0 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.6 KEZ40470.1 - 4.8e-05 23.7 0.0 0.00012 22.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KEZ40470.1 - 0.00012 21.6 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KEZ40470.1 - 0.0031 18.0 0.0 0.006 17.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 KEZ40470.1 - 0.0086 15.9 0.0 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein MeaB PF03308.16 KEZ40470.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Lipase_GDSL PF00657.22 KEZ40472.1 - 1.9e-10 41.1 0.0 2.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KEZ40472.1 - 1.7e-08 35.0 0.1 3.8e-08 33.9 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_76 PF03663.14 KEZ40473.1 - 3.5e-99 332.8 4.8 4.3e-99 332.5 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KEZ40473.1 - 0.013 14.6 0.2 3.6 6.6 0.1 3.1 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.21 KEZ40474.1 - 1.7e-66 224.8 0.0 2.1e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KEZ40474.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.20 KEZ40474.1 - 0.02 13.4 0.1 0.046 12.3 0.0 1.6 2 1 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Acyl_transf_3 PF01757.22 KEZ40476.1 - 6.9e-27 94.4 33.0 2.1e-26 92.8 33.0 1.8 1 1 0 1 1 1 1 Acyltransferase family Tachykinin PF02202.16 KEZ40476.1 - 0.17 11.8 1.2 0.79 9.8 1.2 2.2 1 0 0 1 1 1 0 Tachykinin family Rad51 PF08423.11 KEZ40477.1 - 1.9e-08 33.9 0.0 1.1e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KEZ40477.1 - 0.0001 21.7 0.0 0.00027 20.3 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 KEZ40477.1 - 0.00028 20.5 1.7 0.0013 18.4 0.3 2.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEZ40477.1 - 0.00035 20.4 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RecA PF00154.21 KEZ40477.1 - 0.00043 19.8 0.0 0.0018 17.8 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 KEZ40477.1 - 0.00057 19.3 0.0 0.03 13.6 0.0 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 KEZ40477.1 - 0.016 15.7 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KEZ40477.1 - 0.087 12.5 0.0 0.31 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KEZ40478.1 - 6.4e-08 32.6 15.3 0.0014 19.0 5.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ40478.1 - 1.4e-07 31.6 15.6 1.8e-05 25.0 3.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ40478.1 - 0.0007 20.2 13.0 0.25 12.3 3.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEZ40478.1 - 0.049 13.6 2.1 2.9 8.0 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KEZ40478.1 - 0.079 13.6 0.3 0.079 13.6 0.3 1.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KEZ40478.1 - 0.2 12.0 4.1 0.31 11.4 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KEZ40478.1 - 0.53 10.1 10.5 2.6 7.9 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain TIM21 PF08294.11 KEZ40479.1 - 1.8e-46 157.6 0.0 2.3e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KEZ40479.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.18 KEZ40480.1 - 4.1e-35 120.4 0.1 6.8e-35 119.7 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NMO PF03060.15 KEZ40481.1 - 1.2e-55 189.2 1.5 1.8e-55 188.7 1.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KEZ40481.1 - 8.1e-11 41.5 1.6 1.2e-10 41.0 1.6 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEZ40481.1 - 3.8e-06 26.2 1.9 6.8e-06 25.3 1.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KEZ40481.1 - 0.00091 18.5 0.2 0.0018 17.6 0.2 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 KEZ40481.1 - 0.014 14.5 0.1 0.033 13.4 0.1 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 KEZ40481.1 - 0.022 13.9 1.2 0.038 13.1 1.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Pterin_bind PF00809.22 KEZ40482.1 - 8.1e-78 261.5 0.0 1.1e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KEZ40482.1 - 1.2e-36 125.6 0.0 2.2e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Bromodomain PF00439.25 KEZ40483.1 - 7.8e-17 61.1 0.0 1.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 KEZ40483.1 - 1.8e-06 28.1 0.0 4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Mlh1_C PF16413.5 KEZ40484.1 - 3.8e-94 315.1 0.0 1.8e-93 312.8 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KEZ40484.1 - 8.6e-32 109.3 0.0 1.4e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF202 PF02656.15 KEZ40484.1 - 2.2e-13 50.4 1.8 3.3e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HATPase_c_3 PF13589.6 KEZ40484.1 - 8.4e-12 45.1 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KEZ40484.1 - 0.00019 21.9 0.0 0.00049 20.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin_8 PF13905.6 KEZ40484.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like HEAT PF02985.22 KEZ40486.1 - 0.0017 18.4 1.2 8.9 6.9 0.1 4.5 4 0 0 4 4 4 2 HEAT repeat Serine_rich PF08824.10 KEZ40486.1 - 0.06 13.3 0.4 0.67 9.9 0.0 2.6 3 0 0 3 3 3 0 Serine rich protein interaction domain Cnd1 PF12717.7 KEZ40486.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ40486.1 - 0.13 12.7 3.8 3.2 8.2 1.5 4.1 3 2 0 3 3 3 0 HEAT repeats DNA_pol_phi PF04931.13 KEZ40486.1 - 0.28 9.3 9.5 0.6 8.1 9.5 1.5 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KEZ40486.1 - 0.51 8.8 2.6 5.5 5.4 3.5 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DnaJ PF00226.31 KEZ40487.1 - 1.2e-13 50.9 1.2 5.5e-13 48.8 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain DEAD PF00270.29 KEZ40488.1 - 8e-49 165.8 0.0 2.5e-48 164.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40488.1 - 2.4e-26 92.2 0.0 2.9e-24 85.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KEZ40488.1 - 1.1e-22 80.1 1.7 3.7e-22 78.3 1.7 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain LRIF1 PF15741.5 KEZ40488.1 - 0.17 10.4 7.2 0.32 9.5 7.2 1.4 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Astro_capsid_p PF12226.8 KEZ40488.1 - 2.4 7.2 8.3 3.8 6.6 8.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pes-10 PF07149.11 KEZ40488.1 - 5.3 6.0 7.0 8.6 5.3 7.0 1.2 1 0 0 1 1 1 0 Pes-10 Cation_efflux PF01545.21 KEZ40489.1 - 5.9e-48 163.3 4.0 7.6e-48 162.9 4.0 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KEZ40489.1 - 0.013 14.6 0.7 0.013 14.6 0.7 1.7 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component IML1 PF12257.8 KEZ40490.1 - 3.8e-117 390.5 0.0 5.3e-117 390.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KEZ40490.1 - 2.1e-27 94.9 0.1 4.7e-27 93.8 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Nipped-B_C PF12830.7 KEZ40491.1 - 1.3e-48 165.5 2.0 1.3e-48 165.5 2.0 3.4 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KEZ40491.1 - 3.2e-07 30.5 1.6 6.7e-07 29.5 0.3 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KEZ40491.1 - 3.2e-05 23.8 4.2 0.044 14.1 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KEZ40491.1 - 0.00062 19.8 2.5 0.21 11.6 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KEZ40491.1 - 0.0026 16.4 0.4 0.013 14.1 0.0 2.3 2 1 0 2 2 2 1 Adaptin N terminal region TFIIS_C PF01096.18 KEZ40492.1 - 5.5e-15 54.9 0.6 5.5e-15 54.9 0.6 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.11 KEZ40492.1 - 0.0012 18.7 6.3 0.0031 17.4 0.4 2.3 2 0 0 2 2 2 1 Putative transposase DNA-binding domain RNA_POL_M_15KD PF02150.16 KEZ40492.1 - 0.017 15.0 3.1 0.017 15.0 3.1 2.6 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 KEZ40492.1 - 0.031 14.2 1.4 0.031 14.2 1.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 KEZ40492.1 - 0.13 12.4 0.1 0.13 12.4 0.1 3.1 3 1 1 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KEZ40492.1 - 0.62 9.5 0.2 0.62 9.5 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 KEZ40492.1 - 2.1 8.1 9.3 25 4.7 5.1 2.8 2 1 0 2 2 2 0 Ribosomal protein S27 HypA PF01155.19 KEZ40492.1 - 2.3 8.3 9.6 6.6 6.8 4.8 2.7 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KEZ40492.1 - 5.1 6.9 14.2 0.98 9.2 0.4 3.9 4 0 0 4 4 4 0 zinc-ribbon domain HEAT_2 PF13646.6 KEZ40493.1 - 5e-30 103.7 6.0 2.5e-13 50.2 0.0 4.0 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 KEZ40493.1 - 5.8e-23 79.2 4.9 4.9e-05 23.6 0.2 6.9 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KEZ40493.1 - 1.4e-11 43.6 1.9 0.14 12.5 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KEZ40493.1 - 1.4e-07 31.9 5.1 0.5 10.9 0.1 5.5 4 1 2 6 6 6 3 HEAT-like repeat Cnd1 PF12717.7 KEZ40493.1 - 0.003 17.6 0.0 5.1 7.1 0.0 4.1 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 KEZ40493.1 - 0.011 15.7 1.1 3 8.0 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KEZ40493.1 - 0.1 12.8 0.1 0.59 10.3 0.0 2.3 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cofilin_ADF PF00241.20 KEZ40494.1 - 2.8e-17 62.7 0.0 3.2e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 KEZ40495.1 - 1.8e-17 63.3 0.0 4.3e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 KEZ40495.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain Ras PF00071.22 KEZ40496.1 - 3.5e-58 195.8 0.1 4.1e-58 195.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ40496.1 - 9.9e-20 70.9 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ40496.1 - 1.4e-07 31.1 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEZ40496.1 - 2.1e-05 24.2 0.1 0.00014 21.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEZ40496.1 - 4.8e-05 23.3 0.1 0.2 11.5 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KEZ40496.1 - 0.0029 17.7 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KEZ40496.1 - 0.004 17.2 0.0 0.0081 16.2 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 KEZ40496.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 KEZ40496.1 - 0.088 12.6 2.3 0.65 9.7 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KEZ40496.1 - 0.34 10.6 0.9 2.7 7.7 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 KEZ40497.1 - 2e-33 115.8 0.2 7.4e-33 114.0 0.1 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KEZ40497.1 - 2.1e-16 60.0 0.0 1.9e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KEZ40497.1 - 6.4e-06 26.2 0.2 0.0001 22.4 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KEZ40497.1 - 0.0016 18.5 0.2 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain Roc PF08477.13 KEZ40497.1 - 0.021 15.0 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 KEZ40497.1 - 0.026 14.3 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ40497.1 - 0.038 14.4 0.2 0.2 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 KEZ40497.1 - 0.047 13.9 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 KEZ40497.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.27 KEZ40497.1 - 0.11 13.0 0.0 0.63 10.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KEZ40497.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Kelch_5 PF13854.6 KEZ40499.1 - 8.8e-12 44.7 6.7 5.9e-11 42.1 0.1 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 KEZ40499.1 - 2.2e-05 24.4 3.5 1.3 9.1 0.1 4.6 4 2 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KEZ40499.1 - 0.00046 19.7 0.2 2.2 7.9 0.2 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 KEZ40499.1 - 0.0033 17.7 3.4 1.7 9.0 0.0 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 KEZ40499.1 - 0.0077 16.5 4.8 0.28 11.6 0.1 4.0 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 KEZ40499.1 - 0.011 15.7 4.0 10 6.2 0.1 4.5 5 0 0 5 5 5 0 Kelch motif Phosphoesterase PF04185.14 KEZ40499.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoesterase family Abhydrolase_1 PF00561.20 KEZ40500.1 - 1.2e-16 61.1 0.0 1.5e-15 57.5 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ40500.1 - 7.1e-15 56.2 0.0 3.6e-14 53.9 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ40500.1 - 1.6e-14 53.8 0.0 9.3e-14 51.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KEZ40500.1 - 6.5e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 KEZ40500.1 - 0.0005 19.5 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 KEZ40500.1 - 0.0028 17.6 0.0 0.008 16.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KEZ40500.1 - 0.012 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 KEZ40500.1 - 0.014 15.2 0.0 5.9 6.6 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PorA PF11271.8 KEZ40500.1 - 0.022 14.1 0.4 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Porin PorA Thioesterase PF00975.20 KEZ40500.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 KEZ40500.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 KEZ40500.1 - 0.064 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KEZ40500.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KEZ40500.1 - 0.097 12.2 0.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 KEZ40500.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase PAS_9 PF13426.7 KEZ40501.1 - 1.6e-09 38.0 0.0 4.2e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain RGS PF00615.19 KEZ40501.1 - 1e-07 32.2 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.25 KEZ40501.1 - 0.041 13.9 0.0 0.25 11.3 0.0 2.3 3 0 0 3 3 3 0 PAS fold Glyoxalase PF00903.25 KEZ40502.1 - 1.9e-11 44.3 7.6 9.6e-09 35.5 4.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ40502.1 - 0.0034 17.6 0.3 0.13 12.6 0.1 2.8 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CRAL_TRIO PF00650.20 KEZ40503.1 - 9.8e-26 90.4 0.0 1.3e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEZ40503.1 - 1.5e-09 37.9 0.0 3.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DEAD PF00270.29 KEZ40504.1 - 7.5e-45 152.8 0.0 1.4e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40504.1 - 5.3e-25 87.9 0.0 2.2e-24 86.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEZ40504.1 - 1.1e-22 80.0 0.0 4.5e-22 78.0 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEZ40504.1 - 1.2e-06 28.6 0.1 4.6e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PAPS_reduct PF01507.19 KEZ40505.1 - 4e-27 95.4 0.0 4.7e-19 69.1 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family TetR_C_34 PF17929.1 KEZ40505.1 - 0.0033 17.5 0.1 0.0092 16.1 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain GDP_Man_Dehyd PF16363.5 KEZ40506.1 - 1.9e-49 168.9 0.0 2.7e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEZ40506.1 - 4.4e-48 163.9 0.0 5.3e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ40506.1 - 1e-17 64.1 0.0 1.1e-16 60.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KEZ40506.1 - 1.3e-14 54.0 0.2 1.3e-12 47.5 0.2 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEZ40506.1 - 7.2e-12 45.0 0.0 1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KEZ40506.1 - 2.3e-09 37.0 0.2 5.4e-09 35.8 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEZ40506.1 - 1.3e-07 31.7 0.1 2.5e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KEZ40506.1 - 1.8e-06 27.3 0.1 0.00021 20.6 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KEZ40506.1 - 1.8e-05 24.8 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 KEZ40506.1 - 0.00064 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KEZ40506.1 - 0.0089 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KEZ40506.1 - 0.012 15.2 0.2 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 KEZ40506.1 - 0.024 14.2 0.2 0.14 11.7 0.1 2.1 2 1 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 KEZ40506.1 - 0.096 12.6 0.1 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thrombin_light PF09396.10 KEZ40506.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Thrombin light chain ADH_zinc_N PF00107.26 KEZ40507.1 - 3.6e-28 98.1 0.1 5.6e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ40507.1 - 2.1e-17 64.4 0.1 4.7e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ40507.1 - 8.9e-12 44.9 0.1 4.1e-10 39.5 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KEZ40507.1 - 0.00091 19.1 0.1 0.002 18.0 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 KEZ40507.1 - 0.024 14.1 0.3 0.046 13.2 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase HupF_HypC PF01455.18 KEZ40507.1 - 0.15 12.2 1.5 0.49 10.6 0.1 2.5 3 0 0 3 3 3 0 HupF/HypC family APH PF01636.23 KEZ40510.1 - 5.5e-05 23.2 1.5 0.00011 22.2 0.2 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family TTRAP PF14203.6 KEZ40510.1 - 0.015 15.3 0.3 0.045 13.7 0.3 1.8 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein PI3_PI4_kinase PF00454.27 KEZ40510.1 - 0.11 12.3 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Septin PF00735.18 KEZ40511.1 - 1.2e-118 395.4 0.1 1.2e-118 395.4 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KEZ40511.1 - 2.3e-08 34.1 1.2 4.5e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KEZ40511.1 - 4.2e-05 24.1 1.0 0.022 15.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 KEZ40511.1 - 5e-05 22.9 2.9 0.00056 19.5 0.0 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KEZ40511.1 - 0.00096 18.5 1.8 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KEZ40511.1 - 0.0016 18.3 0.9 0.0016 18.3 0.9 3.3 3 1 0 3 3 2 1 RsgA GTPase AAA_16 PF13191.6 KEZ40511.1 - 0.0019 18.6 0.2 0.0055 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KEZ40511.1 - 0.0027 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KEZ40511.1 - 0.0088 16.3 1.2 0.028 14.7 0.0 2.5 2 2 0 2 2 2 1 AAA domain Ras PF00071.22 KEZ40511.1 - 0.014 15.0 0.1 0.047 13.3 0.0 2.0 2 0 0 2 2 1 0 Ras family AAA_29 PF13555.6 KEZ40511.1 - 0.015 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Exonuc_VII_L PF02601.15 KEZ40511.1 - 0.019 14.6 6.0 0.028 14.0 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 KEZ40511.1 - 0.04 14.4 6.4 8 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ40511.1 - 0.051 14.0 0.8 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KEZ40511.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KEZ40511.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEZ40511.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KEZ40511.1 - 0.12 12.4 8.9 0.91 9.6 0.0 3.5 3 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KEZ40511.1 - 0.35 10.6 3.2 7.3 6.3 0.0 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Caldesmon PF02029.15 KEZ40511.1 - 0.39 9.4 15.8 0.67 8.7 15.8 1.3 1 0 0 1 1 1 0 Caldesmon AAA_32 PF13654.6 KEZ40511.1 - 0.41 9.4 12.4 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 KEZ40511.1 - 0.44 9.6 7.9 0.67 9.0 7.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF87 PF01935.17 KEZ40511.1 - 0.63 10.1 3.9 5.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain IIGP PF05049.13 KEZ40511.1 - 1 8.4 5.4 0.29 10.1 0.2 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF3987 PF13148.6 KEZ40511.1 - 4.5 6.2 9.8 2 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FapA PF03961.13 KEZ40511.1 - 5.4 5.5 8.9 8.2 4.9 8.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KEZ40511.1 - 6.4 6.8 14.9 11 6.1 14.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus S4 PF01479.25 KEZ40512.1 - 1.7e-12 46.9 0.0 5.3e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 KEZ40512.1 - 0.09 12.6 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 S4 domain La PF05383.17 KEZ40513.1 - 3.2e-20 71.9 0.0 5e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KEZ40513.1 - 4.2e-09 36.1 0.2 8.1e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEZ40513.1 - 0.017 15.1 0.1 0.046 13.8 0.1 1.7 1 0 0 1 1 1 0 RNA binding motif DUF2920 PF11144.8 KEZ40513.1 - 0.22 10.7 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Ank_2 PF12796.7 KEZ40514.1 - 8.6e-34 116.0 6.4 0.00066 20.2 0.0 14.9 8 5 7 15 15 15 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ40514.1 - 1.1e-14 54.6 11.2 0.048 14.3 0.0 13.5 15 2 0 15 15 15 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ40514.1 - 4.8e-11 41.9 9.6 1.4 9.7 0.0 15.5 18 0 0 18 18 18 1 Ankyrin repeat Ank_5 PF13857.6 KEZ40514.1 - 6.4e-10 39.1 1.0 0.39 11.1 0.0 10.2 9 1 0 9 9 9 1 Ankyrin repeats (many copies) Ank PF00023.30 KEZ40514.1 - 5.3e-06 26.6 19.5 0.76 10.3 0.0 12.8 16 1 0 16 16 16 2 Ankyrin repeat Sen15 PF09631.10 KEZ40514.1 - 0.06 13.7 0.8 7.5 6.9 0.0 2.8 2 0 0 2 2 2 0 Sen15 protein EF-G-binding_N PF07299.11 KEZ40515.1 - 0.063 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Sugar_tr PF00083.24 KEZ40516.1 - 2.2e-82 277.3 15.4 2.7e-82 277.0 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40516.1 - 4.3e-30 104.8 32.7 5.5e-22 78.2 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ40516.1 - 0.0023 16.4 3.6 0.0023 16.4 3.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Exo5 PF09810.9 KEZ40517.1 - 1.7e-126 422.6 0.0 2.7e-126 422.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease MARVEL PF01284.23 KEZ40518.1 - 8.2e-08 32.4 18.0 1.4e-07 31.6 17.9 1.4 1 1 0 1 1 1 1 Membrane-associating domain DSPc PF00782.20 KEZ40519.1 - 2.1e-08 34.0 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEZ40519.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KEZ40519.1 - 0.029 14.4 0.2 0.049 13.6 0.2 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family UPF0121 PF03661.13 KEZ40520.1 - 5.4e-31 107.8 0.6 6.8e-31 107.5 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Cyclin_N PF00134.23 KEZ40521.1 - 1.9e-10 40.6 0.0 3.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ntox43 PF15537.6 KEZ40521.1 - 0.074 13.1 0.2 0.2 11.7 0.2 1.7 2 0 0 2 2 2 0 Bacterial toxin 43 Palm_thioest PF02089.15 KEZ40522.1 - 4.8e-79 265.6 0.0 5.8e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ribosomal_L1 PF00687.21 KEZ40523.1 - 5.3e-66 222.2 2.9 9.9e-66 221.4 2.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family LRAT PF04970.13 KEZ40523.1 - 0.11 12.9 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DUF2508 PF10704.9 KEZ40523.1 - 0.82 9.9 13.4 0.098 12.8 5.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) zf-RING_2 PF13639.6 KEZ40525.1 - 1.9e-08 34.5 9.0 3.9e-08 33.5 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KEZ40525.1 - 1.5e-06 28.2 8.7 4.6e-06 26.7 8.7 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KEZ40525.1 - 6.2e-05 23.0 2.7 0.00015 21.7 2.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KEZ40525.1 - 0.00033 20.9 8.2 0.00079 19.7 8.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 KEZ40525.1 - 0.00094 19.3 8.0 0.002 18.2 8.0 1.6 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 KEZ40525.1 - 0.026 14.1 5.6 0.061 13.0 5.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KEZ40525.1 - 0.031 14.2 10.1 0.064 13.1 10.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 KEZ40525.1 - 0.031 14.2 6.9 0.019 14.8 4.4 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 KEZ40525.1 - 0.065 13.6 8.4 0.13 12.6 8.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 KEZ40525.1 - 0.11 12.3 6.1 0.22 11.4 6.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ40525.1 - 0.23 11.3 9.4 0.58 10.0 9.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ40525.1 - 1.2 9.1 5.5 2.6 8.0 5.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 KEZ40525.1 - 2 8.6 4.3 5.8 7.1 4.3 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KEZ40525.1 - 2.9 7.8 7.8 6.3 6.8 7.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_9 PF13901.6 KEZ40525.1 - 5.4 6.9 9.8 2.1 8.2 7.0 1.7 2 0 0 2 2 1 0 Putative zinc-RING and/or ribbon Pkinase PF00069.25 KEZ40526.1 - 2.1e-39 135.5 0.0 2.6e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40526.1 - 4.6e-15 55.6 0.0 7e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KEZ40526.1 - 0.16 11.6 0.0 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 muHD PF10291.9 KEZ40527.1 - 2.4e-64 217.3 0.0 4.9e-64 216.3 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KEZ40527.1 - 1.5e-08 34.8 0.9 4.4e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Glycoprotein_G PF00802.19 KEZ40527.1 - 0.22 10.9 2.5 0.59 9.5 2.5 1.7 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Vps5 PF09325.10 KEZ40527.1 - 0.51 9.9 7.8 0.067 12.7 3.7 1.5 2 0 0 2 2 2 0 Vps5 C terminal like TraC PF07820.12 KEZ40527.1 - 0.93 9.9 4.4 0.65 10.4 0.2 2.6 2 0 0 2 2 2 0 TraC-like protein DUF4404 PF14357.6 KEZ40527.1 - 7.6 7.3 10.5 2.1 9.1 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) MAD PF05557.13 KEZ40528.1 - 1.2e-66 225.5 60.9 2.1e-66 224.7 58.3 1.9 1 1 1 2 2 2 2 Mitotic checkpoint protein HAP1_N PF04849.13 KEZ40528.1 - 0.0037 16.5 21.9 0.0037 16.5 21.9 4.3 2 1 0 4 4 4 1 HAP1 N-terminal conserved region Sas6_CC PF18594.1 KEZ40528.1 - 4.8 7.1 9.4 0.71 9.7 0.5 4.0 3 1 1 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain Tam41_Mmp37 PF09139.11 KEZ40529.1 - 3.6e-121 404.6 0.0 4.9e-121 404.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial CBM_1 PF00734.18 KEZ40530.1 - 9.5e-08 31.9 9.3 9.5e-08 31.9 9.3 1.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_transf_22 PF03901.17 KEZ40531.1 - 3.7e-82 276.8 14.9 4.3e-82 276.6 14.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SH3_9 PF14604.6 KEZ40532.1 - 5.1e-11 42.3 0.0 8.1e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ40532.1 - 9.7e-07 28.3 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KEZ40532.1 - 3.7e-06 26.5 0.0 6.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Glycophorin_A PF01102.18 KEZ40532.1 - 0.0012 19.1 0.0 0.0035 17.6 0.0 1.8 1 0 0 1 1 1 1 Glycophorin A Syndecan PF01034.20 KEZ40532.1 - 0.0022 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain DUF5305 PF17231.2 KEZ40532.1 - 0.03 13.7 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SKG6 PF08693.10 KEZ40532.1 - 0.062 12.7 0.2 0.062 12.7 0.2 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF4366 PF14283.6 KEZ40532.1 - 0.067 13.2 0.7 0.31 11.1 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.11 KEZ40532.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Amnionless PF14828.6 KEZ40532.1 - 0.24 10.2 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Nitrate_red_gam PF02665.14 KEZ40532.1 - 0.34 10.4 0.2 0.68 9.4 0.0 1.5 2 0 0 2 2 2 0 Nitrate reductase gamma subunit Podoplanin PF05808.11 KEZ40532.1 - 2.1 8.4 7.0 0.18 11.9 1.0 2.2 3 1 0 3 3 2 0 Podoplanin Mito_carr PF00153.27 KEZ40533.1 - 4.4e-58 193.2 3.6 7e-19 67.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 KEZ40534.1 - 4.5e-06 26.5 0.0 2.6 7.7 0.0 4.2 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.18 KEZ40535.1 - 4.9e-40 137.7 0.2 6.3e-40 137.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.7 KEZ40536.1 - 9.7e-13 48.4 0.0 2.7e-11 43.7 0.0 3.0 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KEZ40536.1 - 6.9e-09 35.6 0.2 2.6e-08 33.7 0.6 1.7 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex zf-NADH-PPase PF09297.11 KEZ40536.1 - 0.096 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Cation_efflux PF01545.21 KEZ40537.1 - 2.4e-45 154.7 5.7 3.4e-45 154.2 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family DUF998 PF06197.13 KEZ40537.1 - 4.6 6.8 8.5 2.1 7.9 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Glyco_trans_1_4 PF13692.6 KEZ40538.1 - 4.1e-07 30.5 0.0 2.2e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ40538.1 - 0.00015 21.4 0.0 0.00043 19.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ40538.1 - 0.0011 19.4 0.1 0.0022 18.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ40538.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 UQ_con PF00179.26 KEZ40539.1 - 3.8e-37 127.1 0.0 4.2e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ40539.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 KEZ40539.1 - 0.058 13.0 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 TP_methylase PF00590.20 KEZ40540.1 - 6.3e-24 85.1 0.1 1e-23 84.4 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pyrid_ox_like PF16242.5 KEZ40541.1 - 1.6e-22 79.7 0.0 2.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KEZ40541.1 - 8.2e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CoA_binding_2 PF13380.6 KEZ40542.1 - 2.4e-28 98.9 0.0 3.1e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.12 KEZ40543.1 - 2.9e-20 72.7 0.0 5.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40543.1 - 1e-17 64.6 0.1 1.9e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40543.1 - 1.7e-11 44.1 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ40543.1 - 2.1e-09 38.0 0.0 3.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ40543.1 - 1.9e-07 30.6 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEZ40543.1 - 6.4e-05 22.9 0.0 8.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KEZ40543.1 - 0.0038 17.1 0.0 0.04 13.8 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 KEZ40543.1 - 0.005 16.4 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KEZ40543.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KEZ40543.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 KEZ40543.1 - 0.036 13.0 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DREV PF05219.12 KEZ40543.1 - 0.046 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 KEZ40543.1 - 0.047 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 KEZ40543.1 - 0.064 12.5 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase EF-hand_9 PF14658.6 KEZ40544.1 - 2.6e-14 53.3 0.0 8.9e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KEZ40544.1 - 4.6e-13 49.4 0.1 3.6e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEZ40544.1 - 1.6e-10 40.0 0.2 0.0043 16.9 0.0 4.0 4 1 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KEZ40544.1 - 1.2e-09 37.0 0.2 0.025 14.1 0.0 4.2 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 KEZ40544.1 - 1.5e-07 31.2 0.1 2e-05 24.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair GPHH PF16905.5 KEZ40544.1 - 0.21 11.4 0.0 0.94 9.3 0.0 2.0 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Peptidase_M3 PF01432.20 KEZ40545.1 - 1.7e-152 508.9 0.0 2.2e-152 508.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 KEZ40545.1 - 0.017 13.8 0.0 0.076 11.6 0.0 1.9 2 0 0 2 2 2 0 Angiotensin-converting enzyme BIR PF00653.21 KEZ40546.1 - 9.1e-43 144.8 3.3 2.4e-20 72.9 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Trypan_PARP PF05887.11 KEZ40546.1 - 0.00032 20.7 30.4 0.00032 20.7 30.4 5.8 2 1 4 6 6 6 1 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 KEZ40547.1 - 6e-13 48.4 29.4 6e-13 48.4 29.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 KEZ40548.1 - 4e-06 26.6 0.7 1.1e-05 25.2 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ40548.1 - 0.00015 21.6 0.6 0.00032 20.5 0.6 1.6 1 0 0 1 1 1 1 F-box domain Glyco_hydro_61 PF03443.14 KEZ40549.1 - 5.8e-63 212.5 0.0 6.9e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KEZ40549.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SUR7 PF06687.12 KEZ40550.1 - 1.3e-12 47.8 0.0 1.9e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family TAF4 PF05236.14 KEZ40550.1 - 0.17 11.6 10.8 0.24 11.1 10.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4887 PF16228.5 KEZ40550.1 - 0.21 11.8 9.5 0.32 11.2 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) PNISR PF15996.5 KEZ40550.1 - 1.1 9.5 18.1 1.6 8.9 18.1 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Vfa1 PF08432.10 KEZ40550.1 - 5.1 7.4 12.2 7.6 6.8 12.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2781 PF10914.8 KEZ40551.1 - 1.6e-35 122.7 8.6 1.8e-35 122.5 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF4516 PF14990.6 KEZ40551.1 - 0.045 13.5 0.8 1.1 9.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) Nucleoporin_N PF08801.11 KEZ40553.1 - 3.2e-96 322.7 0.3 4.5e-96 322.2 0.3 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KEZ40553.1 - 9.6e-49 166.6 0.1 5e-47 160.9 0.0 2.2 1 1 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal adh_short PF00106.25 KEZ40554.1 - 2.7e-40 137.9 0.0 3.5e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ40554.1 - 4.7e-25 88.5 0.0 6e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ40554.1 - 4e-07 30.1 0.1 1e-06 28.8 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ40554.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KEZ40554.1 - 0.048 13.9 0.1 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF2703 PF10865.8 KEZ40554.1 - 0.075 13.2 0.0 6.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Erg28 PF03694.13 KEZ40555.1 - 3e-45 153.1 0.0 3.6e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_tr_C PF02744.17 KEZ40556.1 - 7.7e-58 194.9 0.0 1.4e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 KEZ40556.1 - 3.4e-32 112.4 0.0 9.7e-31 107.6 0.0 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 KEZ40556.1 - 3.3e-06 27.7 0.0 2.8e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KEZ40556.1 - 0.067 13.7 0.0 0.15 12.5 0.0 1.6 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding ZZ PF00569.17 KEZ40557.1 - 8.6e-11 41.5 5.2 1.5e-10 40.7 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 KEZ40557.1 - 1e-08 35.2 0.0 5.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 KEZ40557.1 - 5.7e-07 29.8 0.0 1.7e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SHOCT PF09851.9 KEZ40557.1 - 0.017 14.9 0.7 0.083 12.7 0.7 2.3 1 0 0 1 1 1 0 Short C-terminal domain Rhodanese PF00581.20 KEZ40558.1 - 2.8e-12 47.1 0.1 8.5e-12 45.5 0.1 1.7 1 1 0 1 1 1 1 Rhodanese-like domain YABBY PF04690.13 KEZ40558.1 - 0.097 13.2 0.1 0.12 13.0 0.1 1.2 1 0 0 1 1 1 0 YABBY protein PS-DH PF14765.6 KEZ40559.1 - 9.9e-59 199.0 0.0 1.5e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KEZ40559.1 - 6.3e-54 183.2 0.8 8.7e-54 182.8 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ40559.1 - 1.3e-53 181.6 0.0 3.3e-53 180.3 0.0 1.8 1 0 0 1 1 1 1 KR domain HD_3 PF13023.6 KEZ40559.1 - 2.7e-45 154.3 0.0 4.8e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 HD domain Acyl_transf_1 PF00698.21 KEZ40559.1 - 3.2e-43 148.4 0.0 5.9e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEZ40559.1 - 1.2e-34 118.8 0.0 5.2e-34 116.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEZ40559.1 - 1e-22 80.7 0.0 2.1e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KEZ40559.1 - 1.9e-20 73.4 0.0 5.3e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEZ40559.1 - 1.8e-17 63.5 0.2 7.5e-15 55.1 0.0 3.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ40559.1 - 4.5e-14 53.6 0.0 7e-13 49.8 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KEZ40559.1 - 3.6e-12 46.8 0.0 1.1e-11 45.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40559.1 - 2e-09 37.9 0.0 1e-08 35.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ40559.1 - 7.3e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40559.1 - 2.5e-08 33.8 0.0 4.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HD_2 PF12917.7 KEZ40559.1 - 8.8e-08 32.1 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme PP-binding PF00550.25 KEZ40559.1 - 1.1e-05 25.7 0.0 3.2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KEZ40559.1 - 1.2e-05 25.1 0.1 4e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KEZ40559.1 - 3.9e-05 23.2 0.4 0.00015 21.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_16 PF10294.9 KEZ40559.1 - 0.002 17.9 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase SAT PF16073.5 KEZ40559.1 - 0.022 14.5 0.2 0.059 13.1 0.2 1.6 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 KEZ40559.1 - 0.027 13.8 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NOC3p PF07540.11 KEZ40561.1 - 0.22 12.0 0.0 0.27 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleolar complex-associated protein DUF3433 PF11915.8 KEZ40562.1 - 5.7e-35 119.7 14.3 1.5e-20 73.4 4.8 4.3 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) HRG PF16954.5 KEZ40562.1 - 4.7 7.7 7.4 0.27 11.6 0.7 2.5 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene HAUS6_N PF14661.6 KEZ40563.1 - 5.5e-54 183.2 2.0 5.5e-54 183.2 2.0 1.8 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S21 PF01165.20 KEZ40564.1 - 1.5e-11 43.8 0.6 2.3e-11 43.2 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.17 KEZ40565.1 - 3.3e-15 56.1 0.5 7.5e-15 55.0 0.5 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KEZ40565.1 - 0.086 12.7 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADIP PF11559.8 KEZ40566.1 - 0.0033 17.5 0.8 0.0033 17.5 0.8 2.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding SKA2 PF16740.5 KEZ40566.1 - 0.0069 16.1 1.7 0.13 12.1 0.3 2.8 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 DUF3847 PF12958.7 KEZ40566.1 - 0.13 12.4 5.9 0.37 10.9 3.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) V_ATPase_I PF01496.19 KEZ40566.1 - 0.19 9.6 2.5 0.33 8.8 2.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 KEZ40566.1 - 0.2 12.4 7.4 10 6.9 0.1 3.5 4 0 0 4 4 3 0 Occludin homology domain DUF5082 PF16888.5 KEZ40566.1 - 0.21 11.9 6.5 0.36 11.1 1.1 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 KEZ40566.1 - 0.4 11.2 8.8 0.39 11.3 1.2 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region APG17 PF04108.12 KEZ40566.1 - 0.49 9.5 9.9 14 4.6 6.8 2.9 2 1 0 2 2 2 0 Autophagy protein Apg17 ING PF12998.7 KEZ40566.1 - 0.52 10.9 5.5 20 5.8 0.1 3.8 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Cep57_CLD_2 PF14197.6 KEZ40566.1 - 0.58 10.3 6.9 0.13 12.3 2.1 2.5 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 YscO PF07321.12 KEZ40566.1 - 0.86 9.6 9.9 0.54 10.2 5.8 2.5 2 1 0 2 2 2 0 Type III secretion protein YscO ATG16 PF08614.11 KEZ40566.1 - 1.2 9.4 10.5 1.7 8.9 2.9 2.7 3 0 0 3 3 2 0 Autophagy protein 16 (ATG16) TACC_C PF05010.14 KEZ40566.1 - 1.2 8.9 10.3 7 6.4 5.7 3.2 3 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DASH_Spc19 PF08287.11 KEZ40566.1 - 1.2 9.0 7.2 2.3 8.1 3.3 3.0 2 2 1 3 3 3 0 Spc19 DUF501 PF04417.12 KEZ40566.1 - 1.4 8.8 6.1 4 7.2 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF501) Prefoldin PF02996.17 KEZ40566.1 - 1.4 8.9 6.2 9.5 6.2 0.5 3.2 3 2 0 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 KEZ40566.1 - 1.7 9.1 6.5 21 5.6 0.7 4.2 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) PspA_IM30 PF04012.12 KEZ40566.1 - 1.7 8.2 9.3 3.2 7.3 3.1 3.4 2 1 1 3 3 3 0 PspA/IM30 family GAS PF13851.6 KEZ40566.1 - 2 7.7 10.3 0.16 11.3 2.0 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 KEZ40566.1 - 2.3 8.4 10.9 0.086 13.0 1.7 2.7 3 1 0 3 3 3 0 Tropomyosin like Exonuc_VII_L PF02601.15 KEZ40566.1 - 3.6 7.1 10.3 15 5.1 10.3 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit RsbRD_N PF14361.6 KEZ40566.1 - 3.8 8.2 9.4 0.15 12.8 0.9 2.8 3 1 1 4 4 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF724 PF05266.14 KEZ40566.1 - 5.8 6.7 7.0 2.5 7.9 1.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF724) CCDC-167 PF15188.6 KEZ40566.1 - 8.9 6.7 9.8 1.9 8.9 1.1 3.3 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 CorA PF01544.18 KEZ40567.1 - 3.9e-13 49.4 1.1 1e-12 48.0 1.1 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein VMA21 PF09446.10 KEZ40567.1 - 0.21 11.7 5.1 0.37 10.9 5.1 1.3 1 0 0 1 1 1 0 VMA21-like domain Glyco_hydro_45 PF02015.16 KEZ40568.1 - 1.4e-21 77.4 2.9 1.8e-21 77.1 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Barwin PF00967.17 KEZ40568.1 - 0.0073 16.2 0.1 0.0073 16.2 0.1 1.6 2 0 0 2 2 2 1 Barwin family Pkinase PF00069.25 KEZ40571.1 - 2.6e-69 233.5 0.0 3.4e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40571.1 - 9e-33 113.6 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KEZ40571.1 - 5e-12 46.3 2.1 1.2e-11 45.1 2.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KEZ40571.1 - 3e-06 26.4 0.0 4.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 KEZ40571.1 - 0.0015 18.8 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KEZ40571.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KEZ40571.1 - 0.16 11.3 0.1 0.36 10.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGI PF00342.19 KEZ40572.1 - 1.3e-218 726.5 0.2 1.5e-218 726.3 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mannitol_dh_C PF08125.13 KEZ40573.1 - 6.2e-40 137.2 0.1 9e-40 136.7 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KEZ40573.1 - 5.1e-20 72.2 0.2 7e-19 68.5 0.0 2.6 2 1 1 3 3 3 1 Mannitol dehydrogenase Rossmann domain Coatomer_WDAD PF04053.14 KEZ40574.1 - 1.1e-169 565.2 0.0 3e-169 563.8 0.0 1.7 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 KEZ40574.1 - 8.3e-39 130.9 6.1 1.7e-06 28.7 0.0 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ40574.1 - 3.8e-08 33.5 0.1 3.6 8.0 0.0 6.2 3 3 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ40574.1 - 3.1e-05 22.8 1.3 0.15 10.7 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KEZ40574.1 - 0.0026 17.8 0.2 3.1 7.9 0.0 4.4 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Herpes_TAF50 PF03326.13 KEZ40575.1 - 0.2 10.3 4.5 0.23 10.1 4.5 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF917 PF06032.12 KEZ40576.1 - 1.4e-125 418.8 1.5 2.3e-125 418.1 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KEZ40576.1 - 9.3e-32 110.4 5.4 1e-28 100.4 0.2 3.5 2 1 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ40576.1 - 3.5e-28 98.5 0.1 5.4e-26 91.4 0.0 2.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Pyr_redox_3 PF13738.6 KEZ40576.1 - 7.1e-18 64.9 0.0 7.3e-15 55.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ40576.1 - 1.9e-15 56.9 0.0 1.7e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEZ40576.1 - 1.6e-14 53.3 0.0 1.6e-12 46.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEZ40576.1 - 6.5e-09 35.4 0.1 1.9e-07 30.5 0.1 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEZ40576.1 - 3.6e-06 27.1 0.0 1.5e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ40576.1 - 1.1e-05 25.9 0.1 0.21 12.2 0.0 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ40576.1 - 0.00023 20.6 0.0 0.0048 16.2 0.0 2.8 4 0 0 4 4 4 1 FAD binding domain BcrAD_BadFG PF01869.20 KEZ40576.1 - 0.0004 20.0 3.9 0.0036 16.9 0.0 3.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 KEZ40576.1 - 0.00062 18.5 0.3 0.014 14.0 0.0 2.3 2 0 0 2 2 2 1 MutL protein AlaDh_PNT_C PF01262.21 KEZ40576.1 - 0.00077 18.8 0.1 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEZ40576.1 - 0.0021 16.9 0.4 0.0079 14.9 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein TrkA_N PF02254.18 KEZ40576.1 - 0.0027 18.0 0.2 0.11 12.8 0.0 2.9 3 0 0 3 3 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 KEZ40576.1 - 0.0033 16.8 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KEZ40576.1 - 0.0046 16.1 0.4 0.12 11.4 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEZ40576.1 - 0.0047 16.0 0.1 0.018 14.2 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KEZ40576.1 - 0.0066 16.5 0.0 0.29 11.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF4394 PF14339.6 KEZ40576.1 - 0.0066 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4394) NAD_binding_7 PF13241.6 KEZ40576.1 - 0.011 16.2 0.0 0.61 10.6 0.0 3.2 3 0 0 3 3 3 0 Putative NAD(P)-binding DAO PF01266.24 KEZ40576.1 - 0.017 14.8 0.1 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 KEZ40576.1 - 0.017 15.3 0.0 12 6.0 0.0 3.1 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 KEZ40576.1 - 0.021 14.1 0.0 0.52 9.5 0.0 2.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 KEZ40576.1 - 0.021 14.7 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ROK PF00480.20 KEZ40576.1 - 0.03 13.8 0.0 0.083 12.4 0.0 1.7 1 0 0 1 1 1 0 ROK family Thi4 PF01946.17 KEZ40576.1 - 0.075 12.3 0.0 0.97 8.6 0.0 2.7 2 0 0 2 2 2 0 Thi4 family SnoaL_4 PF13577.6 KEZ40576.1 - 0.075 13.2 0.3 0.39 10.9 0.3 2.3 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 KEZ40576.1 - 0.087 13.5 0.1 0.4 11.3 0.1 2.2 1 0 0 1 1 1 0 SnoaL-like domain Glyco_hydro_61 PF03443.14 KEZ40577.1 - 3.1e-56 190.6 0.1 3.7e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_7 PF13508.7 KEZ40578.1 - 0.004 17.5 0.1 0.0098 16.3 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 KEZ40578.1 - 0.041 14.5 0.0 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) MFS_1 PF07690.16 KEZ40579.1 - 7.9e-19 67.8 15.6 9.5e-13 47.8 5.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ40579.1 - 1.7e-06 27.2 4.2 0.0025 16.8 1.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KEZ40579.1 - 0.0043 15.5 4.8 0.056 11.9 0.2 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.25 KEZ40580.1 - 1.9e-63 214.3 0.0 2.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40580.1 - 4.1e-42 144.2 0.0 5.5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ40580.1 - 2.5e-07 30.3 0.0 4.8e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEZ40580.1 - 0.00026 20.4 0.4 0.00044 19.7 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KEZ40580.1 - 0.009 15.5 0.1 0.022 14.3 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 KEZ40580.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KEZ40580.1 - 0.029 14.0 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KEZ40580.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KEZ40580.1 - 0.26 10.2 2.2 0.21 10.5 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Terpene_synth_C PF03936.16 KEZ40581.1 - 0.0013 18.2 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Phytase PF02333.15 KEZ40583.1 - 1.2e-72 245.0 0.8 6.8e-69 232.6 0.1 2.1 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KEZ40583.1 - 4.2e-05 23.8 37.7 0.023 15.0 15.9 2.6 2 0 0 2 2 2 2 EGF-like domain DUF1996 PF09362.10 KEZ40584.1 - 1.7e-78 263.8 0.8 1.7e-78 263.8 0.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) CFEM PF05730.11 KEZ40585.1 - 5.5e-62 205.8 87.0 1.7e-08 34.4 2.0 9.3 9 1 0 9 9 9 8 CFEM domain XhoI PF04555.13 KEZ40585.1 - 0.0016 18.3 0.0 20 5.0 0.0 5.1 7 0 0 7 7 7 1 Restriction endonuclease XhoI DUF1363 PF07101.11 KEZ40585.1 - 3.6 7.9 9.0 56 4.0 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1363) AA_permease_2 PF13520.6 KEZ40586.1 - 1.1e-35 123.3 42.3 1.1e-35 123.3 42.3 1.6 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 KEZ40586.1 - 3.4e-15 55.6 35.7 3.4e-15 55.6 35.7 2.0 1 1 1 2 2 2 2 Amino acid permease HORMA PF02301.18 KEZ40587.1 - 3.4e-32 111.8 0.0 4.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Corona_nucleoca PF00937.18 KEZ40587.1 - 0.091 11.8 0.4 0.16 11.0 0.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein UCH PF00443.29 KEZ40588.1 - 8.8e-40 136.8 0.0 1.2e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KEZ40588.1 - 6.5e-24 83.4 0.7 5.7e-11 42.1 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 KEZ40588.1 - 5e-23 80.6 0.1 5e-23 80.6 0.1 2.1 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 KEZ40588.1 - 1.1e-21 76.9 11.1 1.1e-18 67.3 1.6 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KEZ40588.1 - 4.6e-17 62.6 0.2 1.2e-15 57.9 0.0 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Eapp_C PF10238.9 KEZ40588.1 - 0.22 11.6 5.0 0.81 9.8 1.8 3.0 2 2 0 2 2 2 0 E2F-associated phosphoprotein NifU_N PF01592.16 KEZ40589.1 - 2.9e-53 179.4 0.0 4.2e-53 178.9 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 KEZ40589.1 - 0.051 13.8 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 TSCPD domain RPE65 PF03055.15 KEZ40590.1 - 3.9e-110 369.2 0.0 4.4e-110 369.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF4131 PF13567.6 KEZ40592.1 - 4.5 6.9 6.7 11 5.7 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) RSN1_7TM PF02714.15 KEZ40593.1 - 1.1e-66 224.9 25.1 3.3e-47 161.1 10.5 2.3 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KEZ40593.1 - 1.2e-26 92.7 0.1 2.6e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 KEZ40593.1 - 6.6e-12 46.0 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TMEM43 PF07787.12 KEZ40593.1 - 1.7 7.9 6.4 4.4 6.6 6.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 43 DEAD PF00270.29 KEZ40594.1 - 1.9e-50 171.1 0.0 6.5e-50 169.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40594.1 - 2.8e-34 117.8 0.0 3.8e-31 107.7 0.1 2.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KEZ40594.1 - 0.011 14.6 0.0 0.048 12.4 0.0 2.1 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 LAP1C PF05609.12 KEZ40594.1 - 1.4 7.9 25.8 2 7.4 25.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 KEZ40594.1 - 4.2 5.8 24.8 6.1 5.3 24.8 1.2 1 0 0 1 1 1 0 Macoilin family Rft-1 PF04506.13 KEZ40595.1 - 2e-142 475.6 1.6 2.4e-142 475.3 1.6 1.0 1 0 0 1 1 1 1 Rft protein DUF2826 PF11442.8 KEZ40595.1 - 0.029 14.2 0.1 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2826) Polysacc_synt_3 PF13440.6 KEZ40595.1 - 0.11 11.7 9.3 0.063 12.5 0.8 3.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 KEZ40595.1 - 3.9 6.8 20.0 0.25 10.7 8.6 3.8 2 2 1 3 3 3 0 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.14 KEZ40596.1 - 1.5e-46 159.0 2.8 2e-46 158.6 2.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KEZ40596.1 - 1.5e-14 53.7 0.0 3.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KEZ40596.1 - 3.9e-11 43.4 6.5 4e-11 43.3 1.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KEZ40596.1 - 3.4e-05 24.3 0.0 9.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KEZ40596.1 - 4.2e-05 23.4 0.0 0.00019 21.3 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 KEZ40596.1 - 0.00043 19.5 0.1 0.28 10.3 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 KEZ40596.1 - 0.017 15.6 0.6 0.097 13.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KEZ40596.1 - 0.031 14.3 3.1 2.7 8.0 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding FPP PF05911.11 KEZ40597.1 - 0.00041 18.7 18.1 0.00095 17.5 17.5 1.7 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 KEZ40597.1 - 0.0088 16.2 21.9 0.0088 16.2 21.9 2.2 2 1 0 2 2 2 1 Tropomyosin like Fib_alpha PF08702.10 KEZ40597.1 - 0.012 15.8 5.5 0.012 15.8 5.5 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 KEZ40597.1 - 0.03 13.7 28.5 0.55 9.6 28.5 2.6 1 1 0 1 1 1 0 Tropomyosin DUF745 PF05335.13 KEZ40597.1 - 0.032 13.9 7.3 0.08 12.7 7.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TMCO5 PF14992.6 KEZ40597.1 - 0.046 13.3 11.8 4.4 6.8 10.7 2.2 1 1 1 2 2 2 0 TMCO5 family Lebercilin PF15619.6 KEZ40597.1 - 0.13 11.9 28.0 1.5 8.4 24.0 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.13 KEZ40597.1 - 0.39 10.8 18.4 0.16 12.0 11.1 3.0 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CENP-Q PF13094.6 KEZ40597.1 - 0.63 10.2 25.8 0.075 13.2 7.9 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.9 KEZ40597.1 - 1.5 9.2 9.6 0.86 9.9 6.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 KEZ40597.1 - 2.4 6.7 12.2 5.8 5.4 12.1 1.6 1 1 0 1 1 1 0 AAA domain FapA PF03961.13 KEZ40597.1 - 2.5 6.6 5.3 3.1 6.3 4.2 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Phage_GP20 PF06810.11 KEZ40597.1 - 3.2 7.5 10.5 2.7 7.8 0.4 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 TMPIT PF07851.13 KEZ40597.1 - 3.6 6.7 10.0 1.1 8.5 6.7 1.7 1 1 1 2 2 2 0 TMPIT-like protein Na_trans_assoc PF06512.13 KEZ40597.1 - 3.8 7.7 6.9 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated DUF724 PF05266.14 KEZ40597.1 - 8 6.2 17.8 8.6 6.1 5.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PspB PF06667.12 KEZ40597.1 - 8.1 6.6 8.6 13 5.9 1.4 3.1 1 1 2 3 3 3 0 Phage shock protein B Fungal_trans PF04082.18 KEZ40598.1 - 9.3e-21 74.0 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40598.1 - 1.9e-08 34.3 10.0 3.2e-08 33.5 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 KEZ40599.1 - 1.5e-41 142.4 0.0 2.3e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEZ40599.1 - 1.1e-13 51.4 0.0 2.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ribosomal_L22 PF00237.19 KEZ40601.1 - 4.3e-19 68.7 0.0 8.4e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CFEM PF05730.11 KEZ40602.1 - 6.3e-08 32.6 10.1 1.1e-07 31.8 10.1 1.4 1 0 0 1 1 1 1 CFEM domain Plasmodium_Vir PF05795.11 KEZ40602.1 - 0.0008 18.9 0.1 0.001 18.6 0.1 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein SKG6 PF08693.10 KEZ40602.1 - 0.006 16.0 3.7 0.006 16.0 3.7 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain PRCC PF10253.9 KEZ40602.1 - 0.013 16.3 6.7 0.017 16.0 6.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TMEM154 PF15102.6 KEZ40602.1 - 0.051 13.5 4.4 0.18 11.7 4.4 1.9 1 1 0 1 1 1 0 TMEM154 protein family Presenilin PF01080.17 KEZ40602.1 - 0.12 11.1 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KEZ40602.1 - 0.13 10.9 5.6 0.17 10.6 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KEZ40602.1 - 0.26 11.2 7.4 0.3 11.0 7.4 1.1 1 0 0 1 1 1 0 SPX domain Nucleo_P87 PF07267.11 KEZ40602.1 - 0.94 8.3 7.3 1.6 7.5 7.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GST_C PF00043.25 KEZ40603.1 - 4.5e-13 49.2 0.0 1.3e-12 47.7 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEZ40603.1 - 3.7e-11 42.9 0.1 1.2e-10 41.2 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEZ40603.1 - 1.6e-07 31.5 0.0 6e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEZ40603.1 - 5.8e-06 26.4 0.0 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEZ40603.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Methyltransf_2 PF00891.18 KEZ40604.1 - 3.9e-18 65.5 0.3 1.8e-17 63.3 0.1 1.9 2 0 0 2 2 2 1 O-methyltransferase domain DUF4423 PF14394.6 KEZ40604.1 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) DUF3208 PF11482.8 KEZ40604.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) AMP-binding PF00501.28 KEZ40605.1 - 1.1e-71 241.6 0.0 1.6e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KEZ40605.1 - 5.1e-19 67.9 0.6 1e-18 66.9 0.2 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KEZ40605.1 - 4.4e-15 56.4 0.6 8.4e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peptidase_M24 PF00557.24 KEZ40606.1 - 5.8e-44 150.3 0.0 7.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KEZ40606.1 - 1.4e-21 76.5 7.8 2.5e-21 75.7 7.8 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KEZ40606.1 - 0.00039 20.4 5.4 0.00039 20.4 5.4 1.9 2 0 0 2 2 2 1 MYND finger PHF5 PF03660.14 KEZ40606.1 - 0.85 9.9 4.4 2.2 8.5 1.3 2.3 2 0 0 2 2 2 0 PHF5-like protein Methyltransf_12 PF08242.12 KEZ40607.1 - 1.1e-18 67.8 0.0 6.5e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain FMO-like PF00743.19 KEZ40607.1 - 1.1e-16 60.4 0.0 1.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Methyltransf_23 PF13489.6 KEZ40607.1 - 5.7e-13 49.0 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40607.1 - 6e-13 49.3 0.0 7.5e-12 45.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox_2 PF07992.14 KEZ40607.1 - 1.5e-10 40.8 0.0 8.1e-09 35.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_11 PF08241.12 KEZ40607.1 - 1.7e-10 41.4 0.0 4.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_3 PF13738.6 KEZ40607.1 - 2e-10 40.4 0.0 4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.6 KEZ40607.1 - 5.9e-09 35.9 0.0 1.7e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_8 PF13450.6 KEZ40607.1 - 3.5e-08 33.5 0.0 8.6e-06 25.9 0.0 3.9 4 1 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Ubie_methyltran PF01209.18 KEZ40607.1 - 4.5e-08 32.7 0.0 9.5e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family K_oxygenase PF13434.6 KEZ40607.1 - 5.7e-05 22.4 0.0 0.00013 21.2 0.0 1.6 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_16 PF10294.9 KEZ40607.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Pyr_redox PF00070.27 KEZ40607.1 - 0.0048 17.4 0.0 7.5 7.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ40607.1 - 0.0048 16.9 0.3 1.4 8.9 0.1 4.1 4 1 0 4 4 3 1 FAD-NAD(P)-binding Methyltransf_28 PF02636.17 KEZ40607.1 - 0.024 14.3 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DAO PF01266.24 KEZ40607.1 - 0.026 14.1 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DREV PF05219.12 KEZ40607.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_24 PF13578.6 KEZ40607.1 - 0.088 13.8 0.0 0.47 11.5 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain YnfE PF17452.2 KEZ40607.1 - 0.089 13.1 0.1 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized YnfE-like 2-Hacid_dh_C PF02826.19 KEZ40607.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ40607.1 - 0.13 12.3 0.2 1.8 8.6 0.0 2.7 4 0 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase RcnB PF11776.8 KEZ40607.1 - 0.24 11.5 1.8 63 3.7 0.3 3.9 3 0 0 3 3 3 0 Nickel/cobalt transporter regulator UbiA PF01040.18 KEZ40608.1 - 4.4e-09 36.0 0.3 4.9e-09 35.8 0.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2627 PF11118.8 KEZ40608.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) DUF981 PF06168.11 KEZ40608.1 - 0.024 14.5 0.2 0.027 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) ABC2_membrane_2 PF12679.7 KEZ40608.1 - 0.042 13.1 0.1 0.047 13.0 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein p450 PF00067.22 KEZ40609.1 - 7.5e-72 242.5 0.0 8.6e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.13 KEZ40610.1 - 3.2e-19 70.0 0.0 5.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EthD PF07110.11 KEZ40611.1 - 8.3e-15 55.7 0.2 1.2e-14 55.2 0.2 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KEZ40611.1 - 0.12 12.9 0.2 0.29 11.6 0.2 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase AMP-binding PF00501.28 KEZ40612.1 - 8e-77 258.6 0.0 1.6e-76 257.6 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 KEZ40612.1 - 5.7e-70 236.2 0.3 1e-69 235.4 0.3 1.3 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 KEZ40612.1 - 2.4e-67 227.2 0.0 2e-66 224.2 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ40612.1 - 4e-55 186.5 0.4 1.3e-53 181.6 0.1 2.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KEZ40612.1 - 2.6e-54 184.5 0.0 4.4e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEZ40612.1 - 3e-38 132.1 0.0 8e-38 130.7 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KEZ40612.1 - 2.1e-33 115.6 0.0 1.1e-32 113.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KEZ40612.1 - 3.9e-31 107.5 0.0 9e-31 106.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KEZ40612.1 - 1.7e-18 66.8 0.4 1.6e-09 38.0 0.1 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 KEZ40612.1 - 1.2e-14 54.2 0.0 1.4e-10 40.9 0.1 3.3 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.21 KEZ40612.1 - 1.2e-13 51.2 0.0 2.9e-09 36.8 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KEZ40612.1 - 6e-11 42.8 0.0 1.1e-09 38.7 0.0 2.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KEZ40612.1 - 1.6e-05 25.5 0.1 0.00026 21.6 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ40612.1 - 0.00016 22.4 0.0 0.00072 20.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 KEZ40612.1 - 0.00023 20.3 0.0 0.047 12.7 0.0 2.7 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ40612.1 - 0.0011 18.5 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 KEZ40612.1 - 0.0043 18.0 0.0 0.014 16.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 KEZ40612.1 - 0.0044 16.2 0.2 0.27 10.3 0.0 2.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Methyltransf_11 PF08241.12 KEZ40612.1 - 0.014 16.1 0.0 0.13 12.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Thiolase_N PF00108.23 KEZ40612.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Semialdhyde_dh PF01118.24 KEZ40612.1 - 0.026 15.0 0.0 6.4 7.2 0.0 2.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 KEZ40613.1 - 2.1e-11 43.9 0.0 2.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40613.1 - 0.00024 21.8 0.0 0.0012 19.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KEZ40613.1 - 0.0064 16.6 0.0 0.027 14.6 0.0 1.8 1 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 KEZ40613.1 - 0.011 15.6 0.0 0.15 11.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40613.1 - 0.18 12.5 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_1 PF00561.20 KEZ40614.1 - 2.2e-09 37.3 0.3 1.3e-08 34.8 0.3 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ40614.1 - 4.2e-09 36.0 0.0 5.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ40614.1 - 1.6e-08 35.5 1.3 2.5e-08 34.8 1.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 KEZ40614.1 - 0.017 14.7 0.1 0.098 12.2 0.1 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family p450 PF00067.22 KEZ40615.1 - 1.5e-27 96.5 0.0 1.8e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_37 PF18665.1 KEZ40615.1 - 0.073 13.7 0.6 0.37 11.4 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ALIX_LYPXL_bnd PF13949.6 KEZ40615.1 - 0.074 12.3 0.0 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV HA2 PF04408.23 KEZ40616.1 - 1.5e-15 57.4 1.1 3.1e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEZ40616.1 - 8.5e-14 51.8 0.0 2.2e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ40616.1 - 1.1e-10 41.6 0.1 2.3e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KEZ40616.1 - 5.6e-09 36.3 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KEZ40616.1 - 8.1e-06 26.2 0.1 2.3e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ40616.1 - 0.0032 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KEZ40616.1 - 0.0047 17.4 0.0 0.016 15.7 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KEZ40616.1 - 0.099 13.2 0.3 6.3 7.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KEZ40616.1 - 0.1 12.5 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KEZ40616.1 - 0.11 11.8 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 KEZ40616.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KEZ40616.1 - 0.16 11.7 0.0 0.46 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gcn1_N PF12074.8 KEZ40617.1 - 6.6e-105 351.3 0.3 6.6e-105 351.3 0.3 4.2 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KEZ40617.1 - 9.4e-60 200.9 5.9 1.9e-59 199.8 5.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KEZ40617.1 - 2.6e-30 101.9 42.0 0.027 14.7 0.1 22.6 26 0 0 26 26 22 7 HEAT repeat HEAT_EZ PF13513.6 KEZ40617.1 - 3.8e-30 103.9 50.6 3.1e-08 33.9 0.1 20.4 19 3 6 25 25 22 6 HEAT-like repeat HEAT_2 PF13646.6 KEZ40617.1 - 1.7e-29 102.1 47.8 2.7e-07 30.9 0.2 15.1 12 4 5 17 17 16 9 HEAT repeats Vac14_Fab1_bd PF12755.7 KEZ40617.1 - 1.1e-12 48.4 0.0 2.6 8.7 0.0 9.3 7 3 2 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KEZ40617.1 - 1.5e-12 47.8 5.3 0.069 13.2 0.4 10.2 6 3 3 11 11 11 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KEZ40617.1 - 4.3e-12 46.5 0.2 0.00062 19.9 0.0 4.8 4 0 0 4 4 4 2 Parkin co-regulated protein CLASP_N PF12348.8 KEZ40617.1 - 1.1e-10 41.4 0.0 0.001 18.7 0.0 6.1 5 1 1 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 KEZ40617.1 - 6.7e-10 38.1 5.8 0.042 12.4 0.3 7.3 5 2 2 8 8 8 3 Adaptin N terminal region UME PF08064.13 KEZ40617.1 - 3.8e-08 33.2 0.1 0.88 9.5 0.0 6.9 6 2 1 7 7 7 2 UME (NUC010) domain DUF937 PF06078.11 KEZ40617.1 - 8.4e-07 29.7 1.1 7 7.3 0.0 6.7 7 1 0 7 7 5 0 Bacterial protein of unknown function (DUF937) Ecm29 PF13001.7 KEZ40617.1 - 3.3e-05 22.8 4.3 0.44 9.2 0.0 5.9 5 2 0 5 5 5 1 Proteasome stabiliser MMS19_C PF12460.8 KEZ40617.1 - 9.2e-05 21.7 16.1 0.073 12.2 0.1 6.7 5 2 1 7 7 7 2 RNAPII transcription regulator C-terminal TIP120 PF08623.10 KEZ40617.1 - 0.00087 19.1 0.1 0.036 13.8 0.0 3.8 4 0 0 4 4 3 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 KEZ40617.1 - 0.001 19.0 0.1 1 9.3 0.0 5.0 6 2 1 7 7 5 1 Domain of unknown function (DUF3385) DRIM PF07539.12 KEZ40617.1 - 0.0027 16.1 5.5 0.53 8.5 0.3 4.1 3 0 0 3 3 3 1 Down-regulated in metastasis Tti2 PF10521.9 KEZ40617.1 - 0.0036 16.9 1.6 1 8.8 0.0 5.0 5 1 0 5 5 5 1 Tti2 family FANCI_S2 PF14676.6 KEZ40617.1 - 0.013 15.8 2.7 1 9.7 0.1 4.5 5 1 0 5 5 3 0 FANCI solenoid 2 Pes-10 PF07149.11 KEZ40617.1 - 0.041 13.0 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Pes-10 TFCD_C PF12612.8 KEZ40617.1 - 0.054 13.3 0.5 1.1 9.0 0.0 3.1 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Ipi1_N PF12333.8 KEZ40617.1 - 0.081 13.5 0.1 1.2 9.7 0.0 3.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.12 KEZ40617.1 - 0.12 12.1 4.4 2.1 8.0 0.2 4.7 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis MnmE_helical PF12631.7 KEZ40617.1 - 0.22 11.7 1.1 22 5.1 0.2 3.6 3 0 0 3 3 3 0 MnmE helical domain HEAT_PBS PF03130.16 KEZ40617.1 - 0.3 11.9 13.2 1.8e+02 3.2 0.1 9.1 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Arm PF00514.23 KEZ40617.1 - 1.1 9.4 10.1 1e+02 3.1 0.0 7.3 7 1 1 8 8 7 0 Armadillo/beta-catenin-like repeat SHMT PF00464.19 KEZ40618.1 - 7.4e-200 663.6 0.0 8.7e-200 663.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase ComS PF17584.2 KEZ40618.1 - 0.018 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacillus competence protein S TAF8_C PF10406.9 KEZ40619.1 - 6.5e-13 49.0 0.1 1.7e-12 47.7 0.1 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KEZ40619.1 - 6.6e-10 38.9 0.0 9.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF5542 PF17696.1 KEZ40619.1 - 1.1 9.4 2.4 1 9.6 0.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5542) WD40 PF00400.32 KEZ40620.1 - 2.9e-44 148.2 25.3 6.9e-08 33.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ40620.1 - 6.3e-09 36.0 0.4 0.11 12.8 0.0 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ40620.1 - 0.00019 20.2 4.9 0.053 12.2 0.1 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ40620.1 - 0.0044 16.0 0.1 9.1 5.1 0.0 3.8 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEZ40620.1 - 0.0076 15.6 0.0 0.47 9.7 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain PD40 PF07676.12 KEZ40620.1 - 0.018 15.0 0.3 22 5.1 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat BATS PF06968.13 KEZ40622.1 - 6.6e-21 74.3 0.0 1.4e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KEZ40622.1 - 5e-15 56.3 0.1 1.1e-14 55.1 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_hydro_6 PF01341.17 KEZ40623.1 - 1.2e-100 337.2 0.4 1.5e-100 336.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.13 KEZ40624.1 - 3.1e-102 341.9 0.0 3.8e-102 341.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Pex14_N PF04695.13 KEZ40624.1 - 0.14 12.9 0.1 0.24 12.1 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_A_type_inc PF04508.12 KEZ40625.1 - 0.019 14.8 4.3 1.6 8.7 0.1 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 KEZ40625.1 - 0.05 13.6 49.6 0.81 9.7 9.9 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FtsJ PF01728.19 KEZ40626.1 - 4.5e-52 176.7 0.0 6e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KEZ40626.1 - 5.9e-05 23.0 0.2 0.0001 22.2 0.2 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40626.1 - 0.13 13.0 0.0 0.94 10.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Ribosomal_L18 PF17135.4 KEZ40627.1 - 1.6e-90 301.5 5.5 1.8e-90 301.4 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KEZ40627.1 - 6.7e-05 23.6 0.2 0.00014 22.6 0.2 1.6 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Mito_carr PF00153.27 KEZ40628.1 - 1.3e-72 239.8 1.0 1.6e-23 82.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEZ40628.1 - 0.00014 21.1 0.1 0.0075 15.5 0.1 2.9 2 1 0 2 2 2 1 Gammaproteobacterial serine protease GAD-like PF08887.11 KEZ40628.1 - 0.064 13.0 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 GAD-like domain RRM_1 PF00076.22 KEZ40629.1 - 2e-08 33.9 0.0 2.8e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEZ40629.1 - 0.033 14.2 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SAPS PF04499.15 KEZ40629.1 - 1 8.1 2.6 1.1 8.0 2.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MBOAT PF03062.19 KEZ40630.1 - 9.8e-33 113.9 12.2 9.8e-33 113.9 12.2 2.8 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KEZ40630.1 - 9.3e-06 25.8 4.0 2.8e-05 24.3 4.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CH PF00307.31 KEZ40631.1 - 4e-70 232.9 0.0 2.3e-18 66.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KEZ40631.1 - 5.9e-07 29.8 0.6 5.1e-06 26.8 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KEZ40631.1 - 2.4e-05 23.6 0.8 0.86 9.3 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KEZ40631.1 - 0.0041 16.9 0.3 0.31 11.1 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain CAMSAP_CH PF11971.8 KEZ40631.1 - 0.096 12.5 0.0 14 5.6 0.0 3.0 3 0 0 3 3 3 0 CAMSAP CH domain DDHD PF02862.17 KEZ40632.1 - 4.4e-60 203.6 0.0 4.4e-60 203.6 0.0 2.7 2 1 0 2 2 2 1 DDHD domain Lipase_3 PF01764.25 KEZ40632.1 - 0.046 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) WWE PF02825.20 KEZ40632.1 - 0.17 12.5 0.3 20 5.9 0.0 2.9 2 0 0 2 2 2 0 WWE domain RNA_pol_Rpb1_5 PF04998.17 KEZ40633.1 - 3.5e-75 252.9 0.2 5.3e-75 252.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KEZ40633.1 - 3.1e-72 242.2 0.0 6.3e-72 241.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KEZ40633.1 - 6e-53 180.2 0.0 4.2e-45 154.4 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KEZ40633.1 - 4.4e-36 124.2 0.0 1.3e-35 122.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KEZ40633.1 - 1.5e-29 102.1 0.3 4.4e-29 100.6 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-tcix PF14952.6 KEZ40633.1 - 0.33 10.6 3.8 0.87 9.2 3.8 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding SRAP PF02586.14 KEZ40634.1 - 2.4e-76 256.1 0.0 8.9e-76 254.3 0.0 1.9 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) GMC_oxred_N PF00732.19 KEZ40635.1 - 1.3e-28 100.3 0.2 4.4e-28 98.5 0.0 2.0 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ40635.1 - 2.7e-24 86.3 0.2 7.5e-24 84.9 0.2 1.8 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ40635.1 - 1.6e-11 44.0 1.0 0.0001 21.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ40635.1 - 5.6e-05 22.9 2.5 0.0022 17.6 2.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ40635.1 - 0.00016 21.8 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ40635.1 - 0.00025 20.4 0.0 0.0005 19.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40635.1 - 0.0019 17.0 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ40635.1 - 0.009 15.3 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ40635.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KEZ40635.1 - 0.018 15.6 0.0 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ40635.1 - 0.027 13.8 0.0 0.64 9.3 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KEZ40635.1 - 0.14 11.2 0.1 0.69 8.9 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_61 PF03443.14 KEZ40636.1 - 4.5e-56 190.0 0.0 5.5e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KEZ40637.1 - 1e-42 146.4 0.1 1.2e-42 146.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alk_phosphatase PF00245.20 KEZ40638.1 - 2.9e-15 56.2 0.5 3.4e-15 55.9 0.5 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Alk_phosphatase PF00245.20 KEZ40639.1 - 4.2e-44 151.1 0.1 4.8e-44 151.0 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Mrr_cat PF04471.12 KEZ40639.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease Peptidase_M28 PF04389.17 KEZ40639.1 - 0.12 12.0 0.2 0.17 11.5 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M28 RNA_pol_Rpb2_6 PF00562.28 KEZ40640.1 - 3.1e-126 421.6 0.2 5.9e-126 420.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KEZ40640.1 - 7e-54 182.4 0.0 1.6e-53 181.3 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KEZ40640.1 - 1.9e-45 154.8 0.1 4.5e-45 153.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KEZ40640.1 - 2.8e-33 114.2 0.1 6.6e-33 113.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KEZ40640.1 - 2e-25 88.7 0.1 6.9e-25 87.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KEZ40640.1 - 2.9e-23 82.2 0.6 8.2e-23 80.7 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KEZ40640.1 - 1.6e-21 76.3 0.5 1.6e-21 76.3 0.5 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_45 PF10385.9 KEZ40640.1 - 0.06 13.6 0.8 1.9 8.8 0.2 2.9 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain PET117 PF15786.5 KEZ40641.1 - 3.7e-25 88.0 2.1 4.3e-25 87.8 2.1 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 KEZ40642.1 - 4.7e-18 65.7 8.3 5.7e-18 65.4 8.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit NYD-SP28 PF14772.6 KEZ40642.1 - 0.0083 16.2 8.3 0.01 15.8 8.3 1.0 1 0 0 1 1 1 1 Sperm tail YusW PF14039.6 KEZ40642.1 - 0.0096 16.4 1.8 0.012 16.1 1.8 1.1 1 0 0 1 1 1 1 YusW-like protein OmpH PF03938.14 KEZ40642.1 - 0.015 15.7 5.4 0.017 15.4 5.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 KEZ40642.1 - 0.021 14.9 0.2 0.024 14.8 0.2 1.0 1 0 0 1 1 1 0 Helicase HerA, central domain RRF PF01765.19 KEZ40642.1 - 0.027 14.4 5.1 0.033 14.1 5.1 1.0 1 0 0 1 1 1 0 Ribosome recycling factor DUF3987 PF13148.6 KEZ40642.1 - 0.072 12.1 3.2 0.083 11.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Apolipoprotein PF01442.18 KEZ40642.1 - 0.097 12.5 7.8 0.11 12.3 7.8 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Atg14 PF10186.9 KEZ40642.1 - 0.3 10.1 2.7 0.38 9.8 2.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 KEZ40642.1 - 1.2 8.5 4.8 1.4 8.2 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CTNNBL PF08216.11 KEZ40643.1 - 2.9e-39 133.4 2.4 3.6e-39 133.1 0.0 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Neurochondrin PF05536.11 KEZ40643.1 - 0.00045 18.7 1.4 0.0018 16.7 0.1 2.0 2 0 0 2 2 2 1 Neurochondrin His_Phos_1 PF00300.22 KEZ40644.1 - 1.4e-11 44.5 0.0 2.5e-11 43.6 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LepA_C PF06421.12 KEZ40645.1 - 2.8e-41 140.0 2.7 5.4e-41 139.1 2.7 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 KEZ40645.1 - 3.7e-35 121.2 0.0 6.9e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEZ40645.1 - 1.2e-20 73.3 0.0 3e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus MIT PF04212.18 KEZ40645.1 - 4.8e-15 55.4 3.1 1.1e-14 54.2 3.1 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain EFG_II PF14492.6 KEZ40645.1 - 1.5e-06 28.2 0.0 5.5e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KEZ40645.1 - 4.8e-06 26.9 0.1 1.2e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 KEZ40645.1 - 0.00089 18.9 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Ras family RF3_C PF16658.5 KEZ40645.1 - 0.0023 17.7 0.0 0.0075 16.1 0.0 1.9 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Glyco_hydro_45 PF02015.16 KEZ40646.1 - 1.1e-79 267.2 17.1 1.7e-79 266.6 17.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 KEZ40646.1 - 3.8e-15 55.5 10.6 3.8e-15 55.5 10.6 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KEZ40646.1 - 0.024 14.9 3.0 0.024 14.9 3.0 3.6 4 0 0 4 4 4 0 Toxin 7 UEV PF05743.13 KEZ40647.1 - 6.6e-37 126.1 0.1 1e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KEZ40647.1 - 9.5e-22 76.7 0.0 1.7e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain HAUS-augmin3 PF14932.6 KEZ40647.1 - 0.2 11.2 0.5 0.31 10.6 0.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 STE2 PF02116.15 KEZ40648.1 - 2.5e-79 266.5 21.5 2.9e-79 266.3 21.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Sec1 PF00995.23 KEZ40649.1 - 2.4e-130 436.5 0.0 2.8e-130 436.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PilO PF04350.13 KEZ40649.1 - 0.12 12.5 0.7 3 8.0 0.1 2.6 2 0 0 2 2 2 0 Pilus assembly protein, PilO zf_CCCH_4 PF18345.1 KEZ40650.1 - 7.9e-06 25.7 3.9 1.3e-05 25.1 3.9 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KEZ40650.1 - 5.2e-05 23.0 2.9 9.4e-05 22.2 2.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEZ40650.1 - 0.00089 19.0 2.0 0.0014 18.4 2.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KEZ40650.1 - 0.007 16.6 0.8 0.017 15.3 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 KEZ40650.1 - 0.045 14.5 0.1 0.045 14.5 0.1 2.6 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 KEZ40650.1 - 0.083 13.4 2.2 0.14 12.7 2.2 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Sas6_CC PF18594.1 KEZ40650.1 - 0.12 12.2 0.3 0.28 11.0 0.3 1.6 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain PK PF00224.21 KEZ40651.1 - 1.3e-167 557.0 4.8 1.7e-167 556.7 4.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KEZ40651.1 - 1.6e-34 118.6 0.0 4.8e-34 117.1 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KEZ40651.1 - 0.0039 16.4 0.5 0.015 14.5 0.3 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family G_glu_transpept PF01019.21 KEZ40652.1 - 8.4e-139 463.6 0.7 1.7e-134 449.5 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.24 KEZ40653.1 - 1.1e-15 57.5 0.0 2.8e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Aldo_ket_red PF00248.21 KEZ40654.1 - 1e-50 172.6 0.0 1.2e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KEZ40655.1 - 1.4e-06 28.1 0.5 1.1e-05 25.2 0.2 2.8 3 1 0 3 3 3 1 F-box-like Cerato-platanin PF07249.12 KEZ40656.1 - 7.9e-52 174.4 0.4 9.1e-52 174.2 0.4 1.0 1 0 0 1 1 1 1 Cerato-platanin FMO-like PF00743.19 KEZ40657.1 - 5.4e-83 279.2 0.0 6.6e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ40657.1 - 5.6e-14 52.1 0.0 3.5e-12 46.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ40657.1 - 7.4e-12 45.1 0.0 1.2e-08 34.5 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ40657.1 - 1.6e-11 44.0 0.0 4.6e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ40657.1 - 6.1e-06 26.4 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEZ40657.1 - 2.4e-05 24.4 0.6 0.0043 17.1 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KEZ40657.1 - 0.0023 17.6 1.3 2 7.9 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ40657.1 - 0.003 18.1 0.1 4.5 7.9 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ40657.1 - 0.074 12.3 0.1 0.39 10.0 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF775 PF05603.12 KEZ40657.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FAD_binding_2 PF00890.24 KEZ40657.1 - 0.18 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Ank_2 PF12796.7 KEZ40658.1 - 7.4e-13 48.9 0.0 3.9e-05 24.2 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ40658.1 - 1.7e-11 44.0 0.8 0.0034 17.7 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KEZ40658.1 - 3.7e-11 43.3 0.2 0.0008 19.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ40658.1 - 3.8e-11 43.0 0.8 7.5e-05 22.9 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ40658.1 - 2.2e-09 36.8 0.1 0.065 13.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KEZ40658.1 - 1.1e-06 28.5 0.3 8e-06 25.7 0.3 2.3 1 1 0 1 1 1 1 KilA-N domain RhoGEF PF00621.20 KEZ40658.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 RhoGEF domain Cu-oxidase_2 PF07731.14 KEZ40659.1 - 1.7e-22 79.6 0.6 8.5e-21 74.1 0.5 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KEZ40659.1 - 1.1e-10 41.8 0.0 2.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase TauD PF02668.16 KEZ40659.1 - 0.096 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family PCRF PF03462.18 KEZ40660.1 - 9.3e-47 159.4 0.6 2e-46 158.3 0.0 1.8 2 1 1 3 3 3 1 PCRF domain RF-1 PF00472.20 KEZ40660.1 - 5.5e-32 110.1 1.7 1.4e-31 108.9 1.7 1.6 1 0 0 1 1 1 1 RF-1 domain Phage_Mu_Gam PF07352.12 KEZ40660.1 - 0.025 14.5 0.2 0.049 13.5 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF4061 PF13270.6 KEZ40660.1 - 0.07 13.4 0.5 0.17 12.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) MIR PF02815.19 KEZ40660.1 - 0.09 12.6 0.4 0.2 11.5 0.4 1.6 1 1 0 1 1 1 0 MIR domain HEAT_2 PF13646.6 KEZ40660.1 - 0.15 12.4 0.2 0.15 12.4 0.2 2.3 2 0 0 2 2 2 0 HEAT repeats Exonuc_VII_L PF02601.15 KEZ40660.1 - 0.17 11.4 3.0 3.9 7.0 0.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit FlgN PF05130.12 KEZ40660.1 - 0.25 11.9 4.2 0.52 10.8 3.5 1.9 1 1 0 1 1 1 0 FlgN protein BNR_2 PF13088.6 KEZ40661.1 - 2e-06 27.3 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KEZ40661.1 - 0.00018 21.0 0.6 0.37 11.0 0.1 3.5 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_3 PF13859.6 KEZ40661.1 - 0.094 12.0 0.1 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 BNR repeat-like domain Sortilin-Vps10 PF15902.5 KEZ40661.1 - 0.12 11.2 0.3 1.7 7.3 0.3 2.2 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, Kinesin PF00225.23 KEZ40662.1 - 5e-110 367.5 1.3 7.1e-110 367.0 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 KEZ40662.1 - 1.1e-40 139.8 1.9 1.8e-40 139.1 0.1 2.3 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KEZ40662.1 - 5.7e-38 130.9 9.6 2.5e-30 105.9 0.1 3.7 3 0 0 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KEZ40662.1 - 1.7e-23 83.2 0.0 4.5e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 KEZ40662.1 - 1.1e-05 25.7 0.1 1.1e-05 25.7 0.1 3.0 3 0 0 3 3 3 1 Kinesin protein 1B PH PF00169.29 KEZ40662.1 - 0.0033 17.9 0.0 0.032 14.7 0.0 2.4 1 1 0 1 1 1 1 PH domain UPF0242 PF06785.11 KEZ40662.1 - 0.059 13.5 11.0 19 5.3 11.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Zw10 PF06248.13 KEZ40662.1 - 4.3 5.8 13.5 0.11 11.1 6.9 1.5 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF87 PF01935.17 KEZ40662.1 - 8 6.5 6.8 46 4.0 0.1 3.0 2 0 0 2 2 2 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 KEZ40662.1 - 8.1 5.9 13.3 3.6 7.1 9.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_M1 PF01433.20 KEZ40663.1 - 6.8e-45 153.3 0.1 9.8e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KEZ40663.1 - 2.2e-37 127.6 0.0 4.2e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KEZ40663.1 - 1.7e-30 106.6 0.0 2.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KEZ40663.1 - 0.082 12.6 0.2 0.85 9.2 0.1 2.4 3 0 0 3 3 3 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 KEZ40663.1 - 0.47 10.9 1.9 9.6 6.6 1.9 2.6 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Uds1 PF15456.6 KEZ40664.1 - 6.4e-34 116.9 8.6 1.7e-33 115.6 8.6 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Spc7 PF08317.11 KEZ40664.1 - 0.093 11.6 1.3 0.17 10.8 1.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Stathmin PF00836.19 KEZ40664.1 - 0.25 11.3 4.0 0.1 12.6 0.6 2.1 2 0 0 2 2 2 0 Stathmin family SSP160 PF06933.11 KEZ40664.1 - 7.7 4.6 27.5 0.27 9.4 3.1 2.4 3 0 0 3 3 3 0 Special lobe-specific silk protein SSP160 Snf7 PF03357.21 KEZ40666.1 - 7.3e-35 120.1 21.3 7.3e-35 120.1 21.3 2.0 1 1 1 2 2 2 1 Snf7 Peptidase_M9_N PF08453.10 KEZ40666.1 - 0.039 13.7 0.7 0.068 12.9 0.7 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Pacs-1 PF10254.9 KEZ40666.1 - 0.043 12.8 1.5 0.063 12.2 1.5 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Peptidase_A3 PF02160.15 KEZ40666.1 - 0.076 12.5 2.2 0.12 11.9 2.2 1.3 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) zf-C4H2 PF10146.9 KEZ40666.1 - 0.35 11.1 18.7 0.71 10.2 18.7 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein GvpL_GvpF PF06386.11 KEZ40666.1 - 0.45 10.4 10.1 0.96 9.3 10.1 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Allexi_40kDa PF05549.11 KEZ40666.1 - 0.78 9.2 6.5 0.55 9.7 4.7 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4795 PF16043.5 KEZ40666.1 - 1.4 8.5 22.2 8.1 6.0 22.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3138 PF11336.8 KEZ40666.1 - 1.5 7.4 9.8 0.65 8.5 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Fmp27_WPPW PF10359.9 KEZ40666.1 - 4 6.2 14.0 5.7 5.7 14.0 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ten1 PF12658.7 KEZ40667.1 - 1.1e-28 99.7 0.0 1.2e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KEZ40667.1 - 0.00097 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Glyco_hydro_10 PF00331.20 KEZ40668.1 - 2.7e-63 214.0 0.1 2.7e-52 177.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 TauD PF02668.16 KEZ40669.1 - 2.1e-28 99.9 0.0 3.3e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidase PF01425.21 KEZ40671.1 - 1.2e-70 238.8 0.0 5.5e-37 127.8 0.0 2.3 1 1 1 2 2 2 2 Amidase Peptidase_M24 PF00557.24 KEZ40672.1 - 7.8e-43 146.6 0.1 1e-42 146.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AhpC-TSA_2 PF13911.6 KEZ40673.1 - 1.1e-15 57.8 0.0 2.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KEZ40673.1 - 0.0001 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ40673.1 - 0.0033 17.2 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin Gp-FAR-1 PF05823.12 KEZ40674.1 - 0.039 14.3 0.1 0.078 13.3 0.1 1.5 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glyco_transf_8 PF01501.20 KEZ40675.1 - 2.9e-15 56.5 0.0 1.6e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KEZ40675.1 - 0.079 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucosyltransferase 24 Mannosyl_trans3 PF11051.8 KEZ40675.1 - 0.19 11.1 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative DUF243 PF03103.17 KEZ40676.1 - 0.041 14.2 0.4 0.054 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF243) WD40 PF00400.32 KEZ40677.1 - 1.7e-17 63.5 9.2 3.8e-05 24.4 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ40677.1 - 1.4e-06 28.5 0.0 0.014 15.7 0.0 4.8 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KEZ40677.1 - 9e-06 25.2 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 KEZ40677.1 - 0.0053 15.8 0.6 0.12 11.3 0.1 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Aminotran_4 PF01063.19 KEZ40679.1 - 2.2e-23 83.3 0.0 2.7e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV CTP_transf_like PF01467.26 KEZ40680.1 - 4.6e-25 88.5 0.0 8e-21 74.7 0.0 4.7 4 0 0 4 4 4 1 Cytidylyltransferase-like MMR_HSR1 PF01926.23 KEZ40680.1 - 2.1e-06 27.8 0.3 5e-05 23.3 0.3 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KEZ40680.1 - 7.5e-06 25.4 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 2 AIG1 family IIGP PF05049.13 KEZ40680.1 - 0.00032 19.9 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) TniB PF05621.11 KEZ40680.1 - 0.00056 19.4 0.0 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 KEZ40680.1 - 0.00069 20.0 0.0 0.0031 17.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ40680.1 - 0.00093 19.1 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 KEZ40680.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 KEZ40680.1 - 0.002 17.6 0.0 0.0062 15.9 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family Septin PF00735.18 KEZ40680.1 - 0.0029 16.9 0.1 0.0084 15.4 0.1 1.7 1 1 0 1 1 1 1 Septin AAA_7 PF12775.7 KEZ40680.1 - 0.0033 17.0 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Dynamin_N PF00350.23 KEZ40680.1 - 0.0051 16.9 0.1 1 9.4 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 KEZ40680.1 - 0.0089 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 KEZ40680.1 - 0.009 15.7 0.0 0.052 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain RasGAP_C PF03836.15 KEZ40680.1 - 0.0093 16.1 7.5 0.37 10.9 0.1 3.5 2 1 0 2 2 2 1 RasGAP C-terminus AAA_22 PF13401.6 KEZ40680.1 - 0.014 15.7 0.0 0.077 13.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEZ40680.1 - 0.014 14.5 0.0 0.044 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.27 KEZ40680.1 - 0.015 14.8 0.0 0.046 13.3 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KEZ40680.1 - 0.032 14.8 0.1 0.26 11.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 KEZ40680.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain G-alpha PF00503.20 KEZ40680.1 - 0.061 12.5 1.4 0.99 8.5 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit DUF4287 PF14117.6 KEZ40680.1 - 0.35 11.0 1.6 3.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) AAA_23 PF13476.6 KEZ40680.1 - 0.48 10.9 0.0 0.48 10.9 0.0 4.4 4 1 0 4 4 4 0 AAA domain MFS_1 PF07690.16 KEZ40681.1 - 1.9e-28 99.4 56.4 1.8e-27 96.2 53.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.8 KEZ40681.1 - 0.00061 18.5 5.7 0.00061 18.5 5.7 2.4 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Spore_III_AF PF09581.10 KEZ40681.1 - 0.22 11.5 0.2 0.5 10.4 0.2 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) OATP PF03137.20 KEZ40681.1 - 0.96 7.7 9.6 2.9 6.1 3.8 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KEZ40682.1 - 8.4e-23 80.9 33.6 2.9e-15 56.0 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ40682.1 - 8.5e-16 57.8 15.0 1.5e-15 57.1 14.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DctQ PF04290.12 KEZ40682.1 - 0.16 11.9 6.4 0.72 9.8 6.4 2.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component ATG2_CAD PF13329.6 KEZ40683.1 - 4.4e-52 175.9 0.1 1e-51 174.8 0.1 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KEZ40683.1 - 4.7e-31 107.0 0.6 1.4e-30 105.5 0.2 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain F420H2_quin_red PF04075.14 KEZ40683.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase Amino_oxidase PF01593.24 KEZ40684.1 - 6.7e-48 164.1 0.0 1.3e-47 163.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ40684.1 - 2.1e-15 56.7 0.0 3.9e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ40684.1 - 2.1e-07 30.5 0.1 3.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40684.1 - 3.3e-05 22.8 0.9 0.0017 17.2 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 KEZ40684.1 - 8.1e-05 23.1 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ40684.1 - 0.00012 21.8 1.1 0.0012 18.5 1.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ40684.1 - 0.00036 19.9 0.3 0.00056 19.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KEZ40684.1 - 0.0007 18.8 0.3 0.0013 17.9 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEZ40684.1 - 0.0036 16.6 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KEZ40684.1 - 0.014 15.4 0.5 0.77 9.7 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KEZ40684.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KEZ40684.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KEZ40684.1 - 0.021 14.7 1.6 0.035 14.0 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KEZ40684.1 - 0.048 12.9 1.1 0.19 10.9 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ40684.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KEZ40684.1 - 0.15 11.1 0.3 0.25 10.4 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Acyl-CoA_dh_1 PF00441.24 KEZ40685.1 - 9.6e-34 116.8 0.6 1.8e-33 115.9 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KEZ40685.1 - 1.6e-20 73.0 0.0 4.3e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KEZ40685.1 - 7e-15 55.0 0.1 1.2e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEZ40685.1 - 5.8e-08 33.4 0.5 2.8e-07 31.2 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEZ40685.1 - 3.4e-06 27.3 0.0 7.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.23 KEZ40686.1 - 2.6e-53 175.8 67.1 3.9e-09 36.2 4.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 KEZ40686.1 - 3.4e-12 45.9 40.8 0.015 15.0 0.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 KEZ40686.1 - 1.3e-07 31.5 51.1 0.3 11.1 0.4 7.1 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KEZ40686.1 - 0.00034 20.2 40.5 0.16 11.7 0.5 7.1 5 2 2 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KEZ40686.1 - 0.00035 20.3 48.0 0.1 12.5 1.3 7.0 5 2 2 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.6 KEZ40686.1 - 0.014 15.2 11.6 0.023 14.5 2.4 6.9 7 0 0 7 7 7 0 Zinc knuckle SAE2 PF08573.10 KEZ40687.1 - 4.7e-40 137.2 0.8 4.7e-40 137.2 0.8 3.3 4 0 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF2353 PF09789.9 KEZ40687.1 - 0.082 12.2 0.2 0.082 12.2 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) DUF4618 PF15397.6 KEZ40687.1 - 0.47 9.8 6.9 1.2 8.5 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) zf-C4H2 PF10146.9 KEZ40687.1 - 1 9.7 6.9 1.9 8.8 0.3 3.0 2 1 0 2 2 2 0 Zinc finger-containing protein LMBR1 PF04791.16 KEZ40687.1 - 1.8 7.4 3.4 2.8 6.8 3.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1465 PF07323.12 KEZ40687.1 - 2 8.2 10.1 1.4 8.7 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Seadorna_VP6 PF07407.11 KEZ40687.1 - 5.9 5.7 7.0 1 8.2 0.4 2.4 3 0 0 3 3 3 0 Seadornavirus VP6 protein NYD-SP28_assoc PF14775.6 KEZ40687.1 - 6.2 7.0 9.4 1.6 8.9 3.6 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Phage_GPO PF05929.11 KEZ40687.1 - 7.5 6.1 12.0 0.52 9.9 0.8 2.5 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase HAUS6_N PF14661.6 KEZ40687.1 - 8.1 6.0 13.4 0.88 9.1 0.6 3.1 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus UCH PF00443.29 KEZ40688.1 - 3e-45 154.7 0.0 4.9e-45 154.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ40688.1 - 4.6e-08 33.0 0.0 4.3e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF952 PF06108.12 KEZ40689.1 - 5.9e-21 74.3 0.0 7.4e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Nucleopor_Nup85 PF07575.13 KEZ40690.1 - 2.5e-15 56.1 0.0 3.7e-13 48.9 0.0 2.6 2 1 0 2 2 2 1 Nup85 Nucleoporin Utp14 PF04615.13 KEZ40690.1 - 0.12 11.0 18.1 0.17 10.5 18.1 1.1 1 0 0 1 1 1 0 Utp14 protein VWD PF00094.25 KEZ40690.1 - 0.23 11.7 0.0 0.4 10.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type D domain XAP5 PF04921.14 KEZ40690.1 - 2.4 7.9 12.6 4 7.2 12.6 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF2722 PF10846.8 KEZ40690.1 - 4.5 6.1 6.3 7 5.5 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNA_pol_phi PF04931.13 KEZ40690.1 - 9 4.3 40.7 15 3.5 40.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi ADH_N PF08240.12 KEZ40691.1 - 2.3e-26 91.8 2.7 7.1e-26 90.2 2.7 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ40691.1 - 2.2e-20 72.9 0.4 4.3e-20 72.0 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ40691.1 - 0.00018 21.1 0.5 0.00086 18.8 0.5 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KEZ40691.1 - 0.00088 18.6 0.8 0.0016 17.8 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KEZ40691.1 - 0.0038 18.3 0.0 0.0094 17.0 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ40691.1 - 0.018 15.3 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KEZ40691.1 - 0.02 14.5 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Imm70 PF15601.6 KEZ40691.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 70 TrkA_N PF02254.18 KEZ40691.1 - 0.093 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain APH PF01636.23 KEZ40692.1 - 0.03 14.2 0.5 0.11 12.4 0.5 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family MARVEL PF01284.23 KEZ40693.1 - 2.2e-13 50.4 10.8 3.2e-13 49.9 10.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4328 PF14219.6 KEZ40693.1 - 0.043 13.4 0.6 0.099 12.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) ABC2_membrane_5 PF13346.6 KEZ40693.1 - 0.21 11.1 7.8 0.25 10.9 7.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF308 PF03729.13 KEZ40693.1 - 5.3 7.4 17.1 0.71 10.2 0.3 3.0 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) APG5 PF04106.12 KEZ40695.1 - 1.6e-44 152.2 0.0 7.3e-44 150.0 0.0 1.8 1 1 0 1 1 1 1 Autophagy protein Apg5 WSC PF01822.19 KEZ40696.1 - 5.9e-15 55.2 10.4 9.5e-15 54.6 10.4 1.3 1 0 0 1 1 1 1 WSC domain Tlr3_TMD PF17968.1 KEZ40696.1 - 0.23 11.7 2.6 0.41 10.9 2.6 1.3 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain WD40 PF00400.32 KEZ40697.1 - 3.7e-25 87.7 14.7 6.6e-05 23.6 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ40697.1 - 9.9e-13 48.2 0.1 0.0043 17.3 0.0 4.8 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ40697.1 - 1.5e-05 23.9 0.4 0.34 9.5 0.0 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ40697.1 - 0.009 15.0 0.0 0.027 13.4 0.0 1.8 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEZ40697.1 - 0.032 14.1 0.0 15 5.4 0.0 2.9 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Zn_clus PF00172.18 KEZ40700.1 - 8e-09 35.5 14.3 1.3e-08 34.8 14.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L22e PF01776.17 KEZ40701.1 - 1.5e-45 154.0 1.7 1.9e-45 153.7 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family S4 PF01479.25 KEZ40702.1 - 1.9e-12 46.7 0.0 5.4e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KEZ40702.1 - 9.9e-11 42.4 0.8 1.5e-10 41.8 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain UPF0302 PF08864.10 KEZ40702.1 - 0.008 16.2 0.1 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 UPF0302 domain THDPS_N_2 PF14805.6 KEZ40702.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF4235 PF14019.6 KEZ40704.1 - 8e-07 29.0 0.7 0.05 13.7 0.1 4.2 4 0 0 4 4 4 3 Protein of unknown function (DUF4235) ABA_WDS PF02496.16 KEZ40704.1 - 5.3e-05 23.6 16.2 0.048 14.1 0.4 4.5 3 1 1 4 4 4 3 ABA/WDS induced protein DUF3824 PF12868.7 KEZ40704.1 - 8.6e-05 23.2 16.5 8.6e-05 23.2 16.5 10.4 5 4 3 10 10 10 3 Domain of unknwon function (DUF3824) PAP_PilO PF06864.12 KEZ40704.1 - 0.14 10.9 1.6 0.54 9.0 0.4 2.3 1 1 0 2 2 2 0 Pilin accessory protein (PilO) Phage_holin_3_3 PF16083.5 KEZ40704.1 - 0.58 10.3 2.4 5.7 7.1 0.0 3.0 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III DnaJ_C PF01556.18 KEZ40705.1 - 1.1e-24 87.2 0.0 1.5e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ40705.1 - 6.7e-24 83.8 2.3 6.7e-24 83.8 2.3 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEZ40705.1 - 2.3e-14 53.5 13.7 3.7e-14 52.8 13.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEZ40705.1 - 9e-07 28.8 7.1 0.0032 17.4 1.4 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KEZ40705.1 - 0.00017 21.6 6.1 0.049 13.7 0.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5351 PF17302.2 KEZ40705.1 - 0.055 13.7 9.8 0.082 13.1 0.2 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5351) TackOD1 PF18551.1 KEZ40705.1 - 0.43 10.2 6.3 1.3 8.7 0.6 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 KEZ40705.1 - 2.1 8.8 11.8 10 6.6 0.2 3.7 2 1 2 4 4 4 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.6 KEZ40705.1 - 6.6 6.7 9.9 3.3 7.6 2.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 KEZ40705.1 - 9.3 6.3 10.6 24 5.0 1.5 2.3 1 1 1 2 2 2 0 zinc-ribbons NRDD PF13597.6 KEZ40705.1 - 9.4 4.9 9.6 7.4 5.2 1.1 2.2 2 0 0 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase Metallophos PF00149.28 KEZ40706.1 - 3.7e-13 50.5 2.0 7.8e-13 49.4 2.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ40706.1 - 6.7e-05 23.1 0.1 0.0029 17.8 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GAF_2 PF13185.6 KEZ40707.1 - 1.1e-08 35.4 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KEZ40707.1 - 0.00063 20.4 0.0 0.00071 20.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain DLH PF01738.18 KEZ40708.1 - 5.8e-15 55.4 0.0 4.9e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family SCP2 PF02036.17 KEZ40709.1 - 3.3e-23 82.1 0.3 3.7e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KEZ40709.1 - 0.00069 19.9 0.1 0.0011 19.3 0.1 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Glyco_hydro_72 PF03198.14 KEZ40710.1 - 4.6e-124 413.8 2.0 5.5e-124 413.5 2.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KEZ40710.1 - 4e-06 26.5 0.7 3.5e-05 23.4 0.7 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FCH PF00611.23 KEZ40711.1 - 3.9e-25 87.9 1.2 7.9e-25 87.0 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KEZ40711.1 - 1e-19 70.1 0.7 2e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KEZ40711.1 - 6e-15 54.9 5.2 9.5e-15 54.2 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 KEZ40711.1 - 2.6e-13 49.3 0.1 2.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 KEZ40711.1 - 0.00029 21.1 0.9 0.034 14.4 0.2 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Allexi_40kDa PF05549.11 KEZ40711.1 - 0.0016 18.0 4.7 0.0079 15.8 0.1 2.4 2 0 0 2 2 2 1 Allexivirus 40kDa protein SH3_2 PF07653.17 KEZ40711.1 - 0.0039 16.8 0.1 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 KEZ40711.1 - 0.004 17.2 0.5 2.5 8.2 0.0 3.7 4 0 0 4 4 4 1 SH3 domain C1_2 PF03107.16 KEZ40711.1 - 0.007 16.7 4.5 0.013 15.8 4.5 1.4 1 0 0 1 1 1 1 C1 domain DUF4482 PF14818.6 KEZ40711.1 - 0.011 16.5 3.3 0.011 16.5 3.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) CENP-Q PF13094.6 KEZ40711.1 - 0.19 11.9 15.1 0.79 9.9 2.9 2.9 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit FYVE PF01363.21 KEZ40711.1 - 0.31 11.2 3.9 0.69 10.1 3.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger DEAD PF00270.29 KEZ40712.1 - 1.6e-33 116.0 0.1 8.9e-33 113.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40712.1 - 1.8e-25 89.4 0.0 3.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ40712.1 - 0.00065 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEZ40712.1 - 0.068 13.4 1.2 1.8 8.9 1.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KEZ40712.1 - 0.095 13.0 0.0 2 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.6 KEZ40712.1 - 0.17 11.2 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CFEM PF05730.11 KEZ40713.1 - 0.036 14.2 7.5 0.066 13.3 7.5 1.5 1 0 0 1 1 1 0 CFEM domain DUF92 PF01940.16 KEZ40714.1 - 5.3e-86 287.9 1.5 6.6e-86 287.6 1.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF4418 PF14387.6 KEZ40714.1 - 0.095 12.9 0.6 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) Fungal_trans PF04082.18 KEZ40715.1 - 4.3e-08 32.5 2.6 2.4e-05 23.5 0.8 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KEZ40716.1 - 3.7e-53 180.5 0.0 6.5e-53 179.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ40716.1 - 1.3e-45 155.2 0.2 1.7e-45 154.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ40716.1 - 2.9e-11 43.6 0.3 4.2e-11 43.1 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ40716.1 - 0.0037 16.8 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KEZ40716.1 - 0.02 15.0 0.3 0.041 14.0 0.1 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 KEZ40716.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SAT PF16073.5 KEZ40717.1 - 3.5e-76 256.1 0.1 9.3e-76 254.7 0.1 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 KEZ40717.1 - 8.7e-73 245.0 0.0 1.8e-72 244.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KEZ40717.1 - 3.1e-43 148.5 0.0 2.5e-42 145.5 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEZ40717.1 - 1.2e-36 125.3 0.6 1.2e-36 125.3 0.6 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KEZ40717.1 - 3.1e-24 86.4 0.5 4.4e-23 82.6 0.0 3.0 3 1 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 KEZ40717.1 - 1.2e-23 83.2 4.4 3e-12 46.7 0.6 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KEZ40717.1 - 3.7e-15 55.9 0.0 6.2e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 KEZ40717.1 - 0.00018 21.0 0.2 0.0031 16.9 0.1 2.8 3 0 0 3 3 3 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KEZ40717.1 - 0.00044 20.7 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KEZ40717.1 - 0.00047 20.8 1.5 0.013 16.1 0.4 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ40717.1 - 0.05 12.9 0.1 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cu-oxidase_3 PF07732.15 KEZ40718.1 - 1e-42 144.9 2.7 6.2e-39 132.7 0.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEZ40718.1 - 1.3e-42 144.8 11.0 6.7e-36 123.1 3.3 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 KEZ40718.1 - 2.8e-21 76.3 0.1 2.9e-20 73.0 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KEZ40718.1 - 0.038 14.1 0.0 4.5 7.4 0.0 3.2 4 0 0 4 4 4 0 Cupredoxin-like domain Glyco_transf_90 PF05686.12 KEZ40719.1 - 1e-20 74.0 0.0 1.6e-16 60.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 ArfGap PF01412.18 KEZ40720.1 - 6e-38 129.5 0.1 1e-37 128.8 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf LETM1 PF07766.13 KEZ40721.1 - 1e-09 38.2 4.2 1.7e-05 24.3 2.1 2.1 1 1 1 2 2 2 2 LETM1-like protein Ran_BP1 PF00638.18 KEZ40722.1 - 1.4e-15 57.6 0.0 4.2e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KEZ40722.1 - 6.8e-07 30.1 74.9 0.00016 22.4 20.5 12.0 3 3 8 11 11 11 5 Nucleoporin FG repeat region F_bP_aldolase PF01116.20 KEZ40723.1 - 8.9e-91 304.2 0.0 9.9e-91 304.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.17 KEZ40723.1 - 0.19 11.2 0.6 0.32 10.5 0.6 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Tfb5 PF06331.12 KEZ40724.1 - 3.1e-24 84.7 1.7 3.4e-24 84.6 1.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH_1 PF00378.20 KEZ40725.1 - 1.1e-42 146.1 0.3 7.5e-42 143.4 0.3 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ40725.1 - 3.1e-31 109.1 0.2 1.2e-27 97.4 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Aldo_ket_red PF00248.21 KEZ40726.1 - 6.9e-69 232.3 0.0 7.8e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.23 KEZ40727.1 - 2.2e-48 160.3 84.4 1.7e-07 31.0 1.6 9.4 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_2 PF13696.6 KEZ40727.1 - 4.6e-13 48.7 74.3 0.0027 17.5 1.0 9.7 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.6 KEZ40727.1 - 3.5e-09 36.3 56.9 0.082 12.7 0.6 9.3 9 0 0 9 9 9 8 Zinc knuckle zf-CCHC_3 PF13917.6 KEZ40727.1 - 3.9e-06 26.7 62.9 0.013 15.5 0.6 8.7 3 3 6 9 9 9 6 Zinc knuckle zf-RING_9 PF13901.6 KEZ40727.1 - 0.00054 20.0 4.5 0.00054 20.0 4.5 4.3 2 2 4 6 6 6 1 Putative zinc-RING and/or ribbon zf-C2H2_10 PF16588.5 KEZ40727.1 - 0.0011 18.7 4.0 0.0011 18.7 4.0 6.8 7 0 0 7 7 7 3 C2H2 zinc-finger PALP PF00291.25 KEZ40729.1 - 1.1e-22 80.8 0.1 1.4e-22 80.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sld5 PF05916.11 KEZ40733.1 - 1.1e-21 77.3 0.0 1.7e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.18 KEZ40734.1 - 1.7e-37 127.7 0.1 2.8e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEZ40734.1 - 4.8e-31 107.1 1.7 8.2e-31 106.3 1.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ASL_C2 PF14698.6 KEZ40735.1 - 1.4e-24 86.6 0.0 4.1e-24 85.1 0.0 1.8 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal OPT PF03169.15 KEZ40736.1 - 2.6e-153 511.9 40.7 3e-153 511.7 40.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Abhydrolase_3 PF07859.13 KEZ40737.1 - 1.6e-31 109.8 0.0 4.7e-31 108.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KEZ40737.1 - 5e-05 22.4 0.0 0.00014 20.9 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Say1_Mug180 PF10340.9 KEZ40737.1 - 0.0013 17.6 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KEZ40737.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEZ40737.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KEZ40737.1 - 0.018 13.7 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 KEZ40737.1 - 0.03 13.8 0.5 0.049 13.1 0.5 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Esterase PF00756.20 KEZ40737.1 - 0.11 12.1 0.0 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 KEZ40737.1 - 0.23 12.0 8.6 0.11 13.1 5.7 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family SAPS PF04499.15 KEZ40738.1 - 2.2e-188 627.0 1.3 3.7e-187 623.0 0.0 3.0 2 2 0 2 2 2 1 SIT4 phosphatase-associated protein Peptidase_S8 PF00082.22 KEZ40739.1 - 5.6e-33 114.5 6.6 8.4e-33 113.9 6.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEZ40739.1 - 2.3e-13 50.6 0.0 3.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 GPHH PF16905.5 KEZ40739.1 - 0.014 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Cyt-b5 PF00173.28 KEZ40740.1 - 4.2e-13 49.3 0.0 9.2e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 KEZ40740.1 - 1.7e-09 37.0 0.0 6.9e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.20 KEZ40740.1 - 6.7e-08 32.4 0.0 2.2e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KEZ40740.1 - 9.6e-08 32.6 0.0 3.5e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-LITAF-like PF10601.9 KEZ40741.1 - 7.5e-24 83.8 9.1 1e-23 83.3 9.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-TFIIB PF13453.6 KEZ40741.1 - 0.00064 19.0 0.4 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor zinc-finger Zn-ribbon_8 PF09723.10 KEZ40741.1 - 0.0069 16.5 1.2 0.75 10.0 0.1 2.6 2 0 0 2 2 2 1 Zinc ribbon domain zf-ISL3 PF14690.6 KEZ40741.1 - 0.024 15.3 4.8 2.6 8.8 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HalOD2 PF18547.1 KEZ40741.1 - 0.2 11.6 2.8 6.3 6.8 0.9 2.6 2 0 0 2 2 2 0 Halobacterial output domain 2 DZR PF12773.7 KEZ40741.1 - 0.25 11.4 8.4 23 5.1 3.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KEZ40741.1 - 0.39 10.2 6.4 0.76 9.3 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 KEZ40741.1 - 0.41 10.6 3.8 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-HIT PF04438.16 KEZ40741.1 - 0.54 10.2 7.7 6 6.8 0.4 2.5 2 1 0 2 2 2 0 HIT zinc finger DUF1610 PF07754.11 KEZ40741.1 - 0.8 9.7 0.1 0.8 9.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.7 KEZ40741.1 - 1.1 9.3 5.5 2.8 8.0 1.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C3HC4_4 PF15227.6 KEZ40741.1 - 1.3 9.3 9.8 0.36 11.0 5.5 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KEZ40741.1 - 1.3 8.9 11.3 12 5.9 11.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 KEZ40741.1 - 1.9 8.5 4.7 6.5 6.8 4.7 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_Rg PF17915.1 KEZ40741.1 - 4.5 6.7 8.7 1.7 8.1 0.1 2.5 3 0 0 3 3 2 0 Reverse gyrase zinc finger CLASP_N PF12348.8 KEZ40742.1 - 4e-06 26.6 0.0 0.0013 18.4 0.1 2.6 2 1 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 KEZ40742.1 - 0.0011 19.0 0.1 0.73 9.9 0.3 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 KEZ40742.1 - 0.0096 16.1 0.0 0.0096 16.1 0.0 2.4 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair HEAT PF02985.22 KEZ40742.1 - 0.046 14.0 1.6 13 6.4 0.1 4.8 6 0 0 6 6 4 0 HEAT repeat Exonuc_VII_L PF02601.15 KEZ40742.1 - 0.051 13.1 0.7 0.17 11.4 0.7 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit HALZ PF02183.18 KEZ40742.1 - 0.056 13.7 14.9 0.15 12.3 4.7 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF812 PF05667.11 KEZ40742.1 - 0.34 9.8 13.3 0.64 8.8 13.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cluap1 PF10234.9 KEZ40742.1 - 0.57 9.5 6.4 1.5 8.2 6.4 1.6 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4407 PF14362.6 KEZ40742.1 - 0.85 8.9 4.0 1.1 8.6 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KEZ40742.1 - 1.3 9.4 9.6 3.6 8.0 9.6 1.7 1 0 0 1 1 1 0 Fez1 DUF3584 PF12128.8 KEZ40742.1 - 2.2 5.7 9.8 3.6 5.0 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_N PF10481.9 KEZ40742.1 - 2.5 7.7 8.5 0.25 10.9 2.3 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain Spc7 PF08317.11 KEZ40742.1 - 2.6 6.8 11.6 5.8 5.7 11.6 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein MCC-bdg_PDZ PF10506.9 KEZ40742.1 - 5.8 7.0 10.6 22 5.1 4.4 3.9 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome HAUS-augmin3 PF14932.6 KEZ40742.1 - 6.9 6.2 12.0 52 3.3 11.7 2.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 NYD-SP28_assoc PF14775.6 KEZ40742.1 - 9.9 6.4 9.5 1.4 9.0 3.3 2.6 2 1 0 2 2 2 0 Sperm tail C-terminal domain SHR-BD PF06650.12 KEZ40743.1 - 5.2e-93 311.3 0.0 1.2e-91 306.8 0.0 2.7 2 1 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KEZ40743.1 - 3.6e-91 304.8 11.1 4.1e-88 294.8 0.2 4.9 5 1 0 6 6 6 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KEZ40743.1 - 4.2e-85 285.3 0.0 1.6e-83 280.1 0.0 3.5 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KEZ40743.1 - 9e-76 253.6 7.4 2.9e-71 238.9 1.2 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KEZ40743.1 - 6.3e-40 135.9 0.0 2e-39 134.3 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KEZ40743.1 - 2.9e-08 34.0 0.3 2.1e-07 31.2 0.0 2.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Nucleos_tra2_C PF07662.13 KEZ40744.1 - 6.2e-66 222.2 1.1 6.2e-66 222.2 1.1 2.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KEZ40744.1 - 1.5e-22 80.0 2.5 1.5e-22 80.0 2.5 3.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KEZ40744.1 - 3.6 7.9 17.9 0.3 11.4 7.5 3.4 2 1 0 2 2 2 0 Nucleoside recognition WSC PF01822.19 KEZ40745.1 - 4.1e-10 39.7 6.7 8.6e-10 38.7 6.7 1.5 1 0 0 1 1 1 1 WSC domain SBP56 PF05694.11 KEZ40746.1 - 6.8e-07 28.5 0.0 4.7e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) Nup160 PF11715.8 KEZ40746.1 - 0.13 10.8 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cupin_1 PF00190.22 KEZ40747.1 - 2.1e-37 128.0 0.0 1.6e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KEZ40747.1 - 1.3e-24 85.6 2.3 1.1e-13 50.7 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KEZ40747.1 - 5.5e-06 26.0 0.0 0.0098 15.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KEZ40747.1 - 4.4e-05 23.4 0.7 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain 3-HAO PF06052.12 KEZ40747.1 - 0.0034 17.0 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.12 KEZ40747.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein dTDP_sugar_isom PF00908.17 KEZ40747.1 - 0.04 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase adh_short PF00106.25 KEZ40748.1 - 9.5e-34 116.6 0.3 1.3e-33 116.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ40748.1 - 1.5e-25 90.1 0.0 2.3e-24 86.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ40748.1 - 5.1e-12 46.1 0.2 8.3e-12 45.4 0.2 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ40748.1 - 8.3e-06 25.1 0.5 1.8e-05 24.1 0.5 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEZ40748.1 - 0.0024 17.4 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KEZ40748.1 - 0.014 15.5 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KEZ40748.1 - 0.019 15.6 1.2 0.1 13.2 0.7 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KEZ40748.1 - 0.037 13.4 0.3 4 6.7 0.0 2.2 2 0 0 2 2 2 0 ThiF family THF_DHG_CYH_C PF02882.19 KEZ40748.1 - 0.09 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_1 PF00175.21 KEZ40749.1 - 2.2e-26 92.6 0.0 8.9e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEZ40749.1 - 1.6e-20 73.3 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEZ40749.1 - 1.3e-06 28.6 0.0 0.00073 19.7 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KEZ40749.1 - 0.054 13.7 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Cyt-b5 PF00173.28 KEZ40750.1 - 4.5e-25 87.6 0.0 5e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2235 PF09994.9 KEZ40753.1 - 1.3e-47 162.6 0.0 2.3e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 KEZ40753.1 - 1.3e-07 31.7 0.0 2.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ40753.1 - 1.7e-06 28.1 0.0 4.1e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KEZ40753.1 - 2.7e-05 24.6 0.0 0.00028 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ40753.1 - 0.00048 20.4 0.0 0.016 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KEZ40753.1 - 0.0018 18.5 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KEZ40753.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KEZ40753.1 - 0.011 16.2 0.0 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 KEZ40753.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KEZ40753.1 - 0.028 13.7 0.0 0.066 12.5 0.0 1.6 1 1 0 1 1 1 0 Septin Dynamin_N PF00350.23 KEZ40753.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Dynamin family AAA_5 PF07728.14 KEZ40753.1 - 0.05 13.6 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KEZ40753.1 - 0.067 12.9 0.1 0.3 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEZ40753.1 - 0.088 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ40753.1 - 0.093 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AIG1 PF04548.16 KEZ40753.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA PF00004.29 KEZ40753.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GST_C_3 PF14497.6 KEZ40754.1 - 2e-07 31.1 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEZ40754.1 - 2.9e-07 30.6 0.1 4.8e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEZ40754.1 - 1.4e-05 25.3 0.0 0.00091 19.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEZ40754.1 - 1.5e-05 25.2 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ40754.1 - 2.9e-05 24.0 0.0 6.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEZ40754.1 - 0.00057 20.2 0.0 0.0018 18.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain HNH_2 PF13391.6 KEZ40755.1 - 8.7e-10 38.6 0.1 1.9e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Translat_reg PF01818.17 KEZ40755.1 - 0.042 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage translational regulator DUF4360 PF14273.6 KEZ40756.1 - 4.6e-61 205.8 3.8 5.2e-61 205.6 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NMO PF03060.15 KEZ40757.1 - 1.2e-31 110.4 8.3 1.6e-23 83.7 6.7 2.9 2 1 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KEZ40757.1 - 5.4e-08 32.2 3.1 0.00071 18.7 2.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEZ40757.1 - 8.8e-07 28.4 1.0 1.4e-06 27.7 1.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 KEZ40757.1 - 3.2e-06 26.4 2.0 4.4e-06 26.0 2.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KEZ40757.1 - 0.029 13.6 0.3 0.046 12.9 0.3 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase SinI PF08671.10 KEZ40757.1 - 0.18 11.6 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 Anti-repressor SinI HRXXH PF13933.6 KEZ40758.1 - 5.4e-105 350.4 0.0 6.5e-105 350.1 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KEZ40758.1 - 0.00025 21.6 0.0 0.00044 20.8 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KEZ40758.1 - 0.011 14.7 0.0 0.02 13.8 0.0 1.4 1 1 0 1 1 1 0 Deuterolysin metalloprotease (M35) family MHYT PF03707.16 KEZ40759.1 - 0.18 12.0 3.6 2.8 8.2 0.4 3.5 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat Tyrosinase PF00264.20 KEZ40760.1 - 4e-27 95.9 0.2 6.9e-27 95.2 0.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase MIP PF00230.20 KEZ40760.1 - 1.3e-19 70.8 7.8 1.9e-19 70.3 7.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein HAD PF12710.7 KEZ40761.1 - 3.3e-21 76.5 0.1 3.2e-19 70.1 0.0 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase UPRTase PF14681.6 KEZ40761.1 - 1.8e-19 70.0 0.0 3.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 KEZ40761.1 - 2.8e-16 60.2 0.0 9.3e-16 58.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.26 KEZ40761.1 - 0.00033 21.0 0.0 0.00051 20.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_18 PF13238.6 KEZ40761.1 - 0.0055 17.2 0.0 0.19 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ40761.1 - 0.068 13.6 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 KEZ40761.1 - 0.069 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain HET PF06985.11 KEZ40762.1 - 1.2e-12 48.4 2.2 1.2e-12 48.4 2.2 4.5 2 2 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF2235 PF09994.9 KEZ40763.1 - 2.8e-73 246.8 0.0 3.7e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 KEZ40764.1 - 1.1e-27 96.8 0.0 1.8e-14 53.2 0.0 3.4 2 1 1 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KEZ40764.1 - 9.2e-05 21.4 0.0 0.00091 18.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 NmrA PF05368.13 KEZ40765.1 - 7.5e-41 140.2 0.0 9.2e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ40765.1 - 2.2e-14 53.8 0.0 3.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ40765.1 - 7.4e-06 25.6 0.1 1.9e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ40765.1 - 0.00052 20.0 0.2 0.00076 19.4 0.2 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KEZ40765.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ40765.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ40765.1 - 0.055 12.6 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.25 KEZ40765.1 - 0.096 12.1 0.1 0.16 11.4 0.1 1.4 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.6 KEZ40766.1 - 4.2e-17 62.6 0.0 5.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ40766.1 - 7.9e-14 51.8 0.0 1.5e-13 50.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEZ40766.1 - 0.00011 21.8 0.1 0.054 12.9 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KEZ40766.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KEZ40767.1 - 5.6e-35 120.6 0.0 7.5e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ40767.1 - 1.6e-27 96.6 0.0 2.1e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KEZ40767.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ40767.1 - 0.00052 19.6 0.0 0.00077 19.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KEZ40767.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 KR domain PAE PF03283.13 KEZ40767.1 - 0.19 10.8 0.6 0.29 10.2 0.6 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Glyco_hydro_16 PF00722.21 KEZ40768.1 - 1e-34 119.6 0.4 1e-34 119.6 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.8 KEZ40768.1 - 0.0024 16.8 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TMEM154 PF15102.6 KEZ40768.1 - 0.55 10.1 3.0 0.91 9.4 3.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family SSP160 PF06933.11 KEZ40768.1 - 1.5 6.9 14.0 2.3 6.3 14.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Metallophos PF00149.28 KEZ40769.1 - 5e-06 27.2 0.4 1.2e-05 26.0 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PRY PF13765.6 KEZ40769.1 - 0.13 11.9 0.2 18 5.1 0.1 2.6 2 0 0 2 2 2 0 SPRY-associated domain COesterase PF00135.28 KEZ40770.1 - 1.1e-42 146.6 0.0 1.1e-42 146.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ40770.1 - 2.5e-06 27.5 0.0 6.9e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ40770.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family AA_permease PF00324.21 KEZ40771.1 - 7.5e-104 348.0 34.7 9e-104 347.7 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ40771.1 - 4.5e-33 114.7 38.1 5.2e-33 114.5 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease Galactosyl_T PF01762.21 KEZ40772.1 - 0.21 11.4 0.2 0.43 10.4 0.1 1.5 1 1 1 2 2 2 0 Galactosyltransferase FAD_binding_3 PF01494.19 KEZ40773.1 - 7.7e-19 68.1 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KEZ40773.1 - 0.0013 18.1 0.2 0.0031 16.9 0.1 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase SE PF08491.10 KEZ40773.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase EthD PF07110.11 KEZ40774.1 - 1.7e-11 45.1 2.2 2.5e-11 44.6 2.2 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KEZ40774.1 - 0.0011 19.4 1.1 0.0047 17.4 1.1 1.9 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase SE PF08491.10 KEZ40778.1 - 9.9e-77 257.7 0.0 1.3e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KEZ40778.1 - 2.2e-12 46.9 0.1 2.1e-11 43.7 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ40778.1 - 5.6e-11 42.6 0.2 1.6e-07 31.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ40778.1 - 8.7e-07 29.1 0.1 1.9e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ40778.1 - 1.8e-06 27.3 0.0 6.7e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ40778.1 - 5e-06 26.0 0.0 8.6e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ40778.1 - 2.7e-05 23.4 0.2 0.00084 18.5 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ40778.1 - 3.8e-05 23.1 0.0 0.0001 21.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KEZ40778.1 - 6.6e-05 22.2 0.0 0.0068 15.5 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ40778.1 - 0.0015 18.0 0.4 0.0023 17.4 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KEZ40778.1 - 0.005 16.9 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KEZ40778.1 - 0.0075 16.8 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40778.1 - 0.018 13.7 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 KEZ40778.1 - 0.03 13.9 0.1 0.06 13.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KEZ40778.1 - 0.045 12.6 0.3 0.093 11.6 0.2 1.6 2 1 0 2 2 2 0 Tryptophan halogenase GDI PF00996.18 KEZ40778.1 - 0.076 11.5 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.18 KEZ40778.1 - 0.093 13.0 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KEZ40778.1 - 0.18 11.0 0.2 0.28 10.4 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KEZ40778.1 - 0.18 12.4 0.1 0.45 11.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KEZ40778.1 - 0.21 10.9 0.4 0.34 10.2 0.4 1.2 1 0 0 1 1 1 0 ThiF family NAD_binding_4 PF07993.12 KEZ40779.1 - 4.7e-31 107.9 0.0 8e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KEZ40779.1 - 2.6e-13 49.4 0.0 4.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KEZ40779.1 - 1.6e-09 37.6 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KEZ40779.1 - 6.2e-05 23.3 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KEZ40779.1 - 0.0021 18.0 0.0 0.039 13.9 0.0 2.8 2 1 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KEZ40779.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEZ40779.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Beta-lactamase PF00144.24 KEZ40780.1 - 4.2e-37 128.1 0.0 6.7e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 KEZ40781.1 - 1.1e-34 119.9 56.0 5.1e-33 114.5 52.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ40781.1 - 8.8e-05 21.5 9.6 8.8e-05 21.5 9.6 2.2 2 0 0 2 2 2 2 MFS_1 like family YtpI PF14007.6 KEZ40781.1 - 0.28 11.4 3.0 2.6 8.2 0.1 3.2 3 0 0 3 3 3 0 YtpI-like protein DHHC PF01529.20 KEZ40781.1 - 5.9 7.0 5.3 82 3.3 4.7 3.0 3 0 0 3 3 3 0 DHHC palmitoyltransferase E1-E2_ATPase PF00122.20 KEZ40782.1 - 4.8e-45 153.3 3.8 1.3e-44 151.8 3.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ40782.1 - 1.7e-25 90.5 0.1 3.6e-25 89.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEZ40782.1 - 6.5e-06 26.5 0.2 2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KEZ40782.1 - 0.022 14.5 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KEZ40782.1 - 0.21 11.1 0.0 0.82 9.1 0.0 1.9 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase SCAMP PF04144.13 KEZ40782.1 - 2.2 8.5 8.4 0.26 11.6 3.1 2.1 2 0 0 2 2 2 0 SCAMP family DUF1264 PF06884.11 KEZ40783.1 - 5.8e-46 156.2 0.4 6.5e-46 156.0 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Methyltransf_23 PF13489.6 KEZ40784.1 - 1.2e-18 67.5 0.0 1.7e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40784.1 - 4.3e-09 36.9 0.0 8.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ40784.1 - 6.5e-05 23.6 0.0 0.00014 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40784.1 - 6.8e-05 22.7 0.0 0.00024 20.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40784.1 - 0.00066 20.3 0.0 0.0018 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ40784.1 - 0.00085 18.7 0.0 0.0083 15.5 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KEZ40784.1 - 0.0089 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 KEZ40784.1 - 0.027 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.14 KEZ40784.1 - 0.051 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.10 KEZ40784.1 - 0.073 12.6 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_20 PF12147.8 KEZ40784.1 - 0.19 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.22 KEZ40785.1 - 2.3e-73 247.5 0.0 3.1e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VDE PF07137.11 KEZ40786.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 VDE lipocalin domain Cutinase PF01083.22 KEZ40788.1 - 7.7e-35 120.5 2.6 9.2e-35 120.2 2.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KEZ40788.1 - 0.064 12.8 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain FAD_binding_3 PF01494.19 KEZ40789.1 - 4.9e-75 253.0 0.0 6.1e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ40789.1 - 7.2e-09 35.7 0.1 0.00027 20.6 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ40789.1 - 3.2e-06 26.6 0.0 0.0034 16.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ40789.1 - 2e-05 23.8 0.0 0.0014 17.8 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 KEZ40789.1 - 4.4e-05 24.0 0.0 0.034 14.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ40789.1 - 0.00024 21.3 0.0 0.00096 19.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ40789.1 - 0.00032 20.0 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KEZ40789.1 - 0.00036 19.9 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ40789.1 - 0.00055 19.1 0.0 0.001 18.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ40789.1 - 0.00076 18.3 0.0 0.011 14.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein PutA_N PF18083.1 KEZ40789.1 - 0.04 13.9 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 Proline utilization A N-terminal domain NAD_binding_9 PF13454.6 KEZ40789.1 - 0.088 12.8 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KEZ40789.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 KEZ40789.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cupin_5 PF06172.11 KEZ40791.1 - 9.6e-41 139.3 0.0 1.2e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) ArAE_2_N PF10337.9 KEZ40792.1 - 5.5e-111 371.9 0.0 2.8e-108 363.0 0.1 3.6 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KEZ40792.1 - 2.1e-62 211.0 0.0 8.9e-62 208.9 0.0 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KEZ40792.1 - 3.9e-09 36.7 15.1 3.9e-09 36.7 15.1 3.0 3 0 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 KEZ40792.1 - 3.6e-08 32.4 4.7 2.9e-06 26.2 0.1 3.3 3 1 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 KEZ40792.1 - 0.064 12.1 1.3 0.29 9.9 1.3 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter BROMI PF14961.6 KEZ40792.1 - 0.068 10.6 0.1 0.095 10.1 0.1 1.1 1 0 0 1 1 1 0 Broad-minded protein Ribosomal_S21 PF01165.20 KEZ40792.1 - 0.23 11.2 0.5 0.51 10.1 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein S21 Oxidored_FMN PF00724.20 KEZ40793.1 - 1.2e-43 149.7 0.0 1.5e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KEZ40793.1 - 0.19 10.8 0.1 0.64 9.0 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Goodbye PF17109.5 KEZ40794.1 - 3e-32 111.6 0.0 2.3e-31 108.7 0.0 2.7 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 KEZ40794.1 - 1.1e-11 44.8 4.2 9.2e-09 35.5 0.4 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ40794.1 - 1.3e-11 43.6 12.1 0.00052 19.9 0.5 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ40794.1 - 6.5e-07 29.9 6.7 0.0039 17.8 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ40794.1 - 1.9e-06 27.5 5.3 0.0053 16.7 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ40794.1 - 9.7e-06 26.0 13.7 0.0013 19.3 0.8 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ40794.1 - 1.3e-05 25.0 8.9 0.002 18.2 0.3 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ40794.1 - 0.00034 20.3 10.1 0.87 9.5 0.4 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ40794.1 - 0.00041 19.7 1.2 0.00041 19.7 1.2 3.1 2 2 2 4 4 4 1 Tetratricopeptide repeat Sec34 PF04136.15 KEZ40794.1 - 0.0012 18.8 0.4 0.016 15.1 0.3 3.0 2 0 0 2 2 2 1 Sec34-like family ANAPC3 PF12895.7 KEZ40794.1 - 0.0045 17.2 1.0 2.4 8.4 0.1 3.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KEZ40794.1 - 0.018 15.4 1.9 1.6 9.1 0.6 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_25 PF13481.6 KEZ40794.1 - 0.027 14.1 0.0 0.093 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain TPR_6 PF13174.6 KEZ40794.1 - 0.059 14.0 7.0 5.4 7.9 0.4 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ40794.1 - 0.062 13.7 4.8 0.97 10.0 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ40794.1 - 0.073 13.0 10.1 2.4 8.1 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ40794.1 - 0.3 11.6 16.7 0.74 10.4 1.8 5.0 4 2 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ40794.1 - 2.2 8.6 0.0 2.2 8.6 0.0 4.2 4 1 0 4 4 4 0 AAA ATPase domain DUF1996 PF09362.10 KEZ40795.1 - 3.2e-46 158.2 0.0 4e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) 4HBT_2 PF13279.6 KEZ40796.1 - 0.00017 22.1 0.0 0.0004 20.9 0.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily Isochorismatase PF00857.20 KEZ40798.1 - 4.7e-13 49.7 0.0 1.1e-12 48.5 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family Acetyltransf_3 PF13302.7 KEZ40799.1 - 2.6e-10 41.1 0.0 3.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 KEZ40800.1 - 6.4e-10 39.0 8.0 6.4e-10 39.0 8.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASFV_J13L PF05568.11 KEZ40801.1 - 0.0063 16.3 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 African swine fever virus J13L protein Pyr_redox_2 PF07992.14 KEZ40803.1 - 1.2e-30 106.8 2.0 1.6e-30 106.4 2.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ40803.1 - 5.5e-10 39.7 2.2 9.4e-08 32.5 0.5 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ40803.1 - 2.1e-08 33.7 0.1 2.9e-06 26.6 0.1 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEZ40803.1 - 0.00079 19.4 5.4 0.25 11.3 0.1 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ40803.1 - 0.003 16.7 3.0 0.0037 16.4 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein TrkA_N PF02254.18 KEZ40803.1 - 0.0046 17.2 0.4 0.18 12.0 0.2 2.6 2 0 0 2 2 2 1 TrkA-N domain DUF3236 PF11576.8 KEZ40803.1 - 0.027 14.2 0.1 0.37 10.5 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3236) Shikimate_DH PF01488.20 KEZ40803.1 - 0.047 13.7 0.4 7.8 6.6 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ40803.1 - 0.13 12.5 2.3 0.76 10.0 0.0 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 KEZ40803.1 - 0.48 9.9 6.8 9 5.8 0.3 3.5 4 0 0 4 4 4 0 FAD dependent oxidoreductase NACHT PF05729.12 KEZ40804.1 - 4e-06 26.9 0.1 3.9e-05 23.6 0.1 2.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ40804.1 - 0.00034 21.0 2.6 0.0032 17.9 0.0 3.9 5 1 0 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 KEZ40804.1 - 0.016 15.4 0.0 0.065 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ40804.1 - 0.027 15.0 0.1 0.41 11.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KEZ40804.1 - 0.032 14.0 0.4 0.07 12.9 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hpt PF01627.23 KEZ40804.1 - 0.032 14.5 2.1 0.093 13.0 0.1 2.9 2 0 0 2 2 2 0 Hpt domain AAA_18 PF13238.6 KEZ40804.1 - 0.039 14.5 0.0 0.15 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ40804.1 - 0.082 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Herpes_UL51 PF04540.13 KEZ40804.1 - 0.11 12.2 0.1 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus UL51 protein Nsp1_C PF05064.13 KEZ40804.1 - 0.13 12.0 0.2 0.51 10.2 0.2 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region ATP_bind_1 PF03029.17 KEZ40804.1 - 0.18 11.6 0.1 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KEZ40804.1 - 0.3 11.6 1.0 1.1 9.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain adh_short_C2 PF13561.6 KEZ40805.1 - 2e-56 191.2 0.5 2.2e-56 191.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ40805.1 - 2.2e-41 141.5 0.3 2.7e-41 141.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ40805.1 - 2.6e-09 37.2 0.9 3.7e-09 36.7 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEZ40805.1 - 0.0021 18.0 0.2 0.0039 17.1 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChuX_HutX PF06228.13 KEZ40805.1 - 0.0028 17.4 0.1 0.18 11.6 0.0 2.3 1 1 1 2 2 2 1 Haem utilisation ChuX/HutX THF_DHG_CYH_C PF02882.19 KEZ40805.1 - 0.045 13.1 0.3 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_12 PF08242.12 KEZ40805.1 - 0.098 13.4 0.1 0.67 10.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.22 KEZ40806.1 - 1.8e-133 445.5 0.0 2e-133 445.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEZ40806.1 - 0.0033 16.5 0.2 0.016 14.2 0.2 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KEZ40806.1 - 0.01 15.3 0.0 0.077 12.4 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Fungal_trans_2 PF11951.8 KEZ40807.1 - 7.8e-39 133.6 1.3 1.2e-38 133.0 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40807.1 - 5.8e-08 32.7 12.8 1e-07 32.0 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gln-synt_C PF00120.24 KEZ40808.1 - 1.1e-69 235.1 0.0 1.4e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 KEZ40808.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain H_lectin PF09458.10 KEZ40809.1 - 2.2e-22 79.0 0.4 8.9e-11 41.8 0.0 2.7 2 0 0 2 2 2 2 H-type lectin domain Peptidase_S8 PF00082.22 KEZ40809.1 - 0.00024 20.4 0.1 0.00052 19.4 0.1 1.5 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 KEZ40813.1 - 1.6e-32 112.8 29.4 9.3e-32 110.3 28.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ40813.1 - 0.0095 14.8 12.4 0.095 11.5 13.8 2.0 2 1 0 2 2 2 1 MFS_1 like family ASFV_J13L PF05568.11 KEZ40814.1 - 0.18 11.6 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein Paramyxo_C PF01692.18 KEZ40814.1 - 0.2 11.0 1.5 7.4 5.9 0.1 2.2 2 0 0 2 2 2 0 Paramyxovirus non-structural protein C 7tm_1 PF00001.21 KEZ40814.1 - 0.48 9.7 4.8 0.12 11.7 0.3 2.0 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Serinc PF03348.15 KEZ40814.1 - 5 6.0 7.7 0.78 8.6 3.9 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) Frag1 PF10277.9 KEZ40814.1 - 7 6.1 11.9 8.2 5.9 3.2 3.0 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family FAD_binding_3 PF01494.19 KEZ40815.1 - 1.8e-16 60.4 0.0 5.2e-10 39.1 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEZ40815.1 - 2.8e-05 24.3 0.0 6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ40815.1 - 0.0004 20.1 0.1 0.0011 18.6 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ40815.1 - 0.0017 17.7 0.0 0.7 9.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ40815.1 - 0.046 14.3 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ40815.1 - 0.059 12.6 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ40815.1 - 0.12 12.4 0.1 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pkinase PF00069.25 KEZ40816.1 - 6.4e-24 84.7 0.0 8.3e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ40816.1 - 4.2e-14 52.5 0.0 5.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ40816.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase MMR_HSR1 PF01926.23 KEZ40817.1 - 4.7e-12 46.0 0.1 5.7e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEZ40817.1 - 1.2e-07 32.0 0.8 0.0068 16.5 0.1 2.1 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KEZ40817.1 - 1.6e-07 30.8 0.0 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KEZ40817.1 - 4e-07 29.7 0.0 4.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEZ40817.1 - 5.4e-05 23.2 0.8 0.00015 21.7 0.8 1.7 1 1 0 1 1 1 1 RsgA GTPase Septin PF00735.18 KEZ40817.1 - 0.001 18.5 0.3 0.0018 17.6 0.3 1.4 1 1 0 1 1 1 1 Septin ATP_bind_1 PF03029.17 KEZ40817.1 - 0.002 18.0 1.9 0.048 13.4 0.8 2.0 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 KEZ40817.1 - 0.0045 16.5 0.0 0.0054 16.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KEZ40817.1 - 0.0048 16.1 0.2 0.0075 15.5 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 KEZ40817.1 - 0.0087 16.6 0.4 0.012 16.1 0.4 1.3 1 1 0 1 1 1 1 ABC transporter Arf PF00025.21 KEZ40817.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family IIGP PF05049.13 KEZ40817.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.18 KEZ40817.1 - 0.039 13.7 0.0 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 KEZ40817.1 - 0.056 13.1 3.5 0.32 10.6 1.6 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 KEZ40817.1 - 0.058 13.0 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KEZ40817.1 - 0.06 13.3 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEZ40817.1 - 0.072 12.8 0.8 0.14 11.9 0.6 1.5 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 KEZ40817.1 - 0.095 13.2 0.5 0.1 13.1 0.5 1.3 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 KEZ40817.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KEZ40817.1 - 0.1 12.5 0.3 0.23 11.4 0.3 1.6 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 KEZ40817.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Gtr1_RagA PF04670.12 KEZ40817.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DLIC PF05783.11 KEZ40817.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MobB PF03205.14 KEZ40817.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KEZ40817.1 - 0.13 12.5 0.4 0.19 11.8 0.4 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KEZ40817.1 - 0.17 11.4 1.8 2.7 7.5 0.3 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AMP-binding PF00501.28 KEZ40819.1 - 5.1e-76 256.0 0.0 1.5e-75 254.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KEZ40819.1 - 7.4e-75 251.8 0.0 3e-74 249.8 0.0 2.1 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KEZ40819.1 - 1.1e-64 218.8 0.0 2.4e-64 217.7 0.0 1.5 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KEZ40819.1 - 1.2e-51 175.2 1.0 4.8e-51 173.2 0.0 2.6 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 KEZ40819.1 - 2e-49 168.4 0.0 5.2e-49 167.1 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEZ40819.1 - 1.3e-32 113.6 0.5 1e-29 104.1 0.4 2.4 1 1 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KEZ40819.1 - 4.1e-29 101.5 0.0 1.5e-28 99.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KEZ40819.1 - 1.5e-22 79.7 0.4 2.3e-10 40.7 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KEZ40819.1 - 3.1e-20 72.8 0.0 1.2e-19 70.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEZ40819.1 - 4.3e-15 56.1 0.0 8.2e-14 52.0 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 KEZ40819.1 - 5.8e-15 55.4 0.0 1.6e-08 34.3 0.0 2.8 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Ketoacyl-synt_C PF02801.22 KEZ40819.1 - 2.2e-14 53.5 0.0 2.2e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_25 PF13649.6 KEZ40819.1 - 2e-12 47.6 0.0 8.2e-12 45.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ40819.1 - 2e-12 47.3 0.0 4.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40819.1 - 2.1e-12 47.1 0.0 5.7e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40819.1 - 2.6e-10 40.8 0.0 9.6e-10 39.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KEZ40819.1 - 1.2e-08 34.7 0.0 5e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KEZ40819.1 - 2e-08 34.0 0.0 6e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ40819.1 - 5e-08 32.3 0.0 3.2e-06 26.4 0.0 2.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 KEZ40819.1 - 1.3e-07 31.2 0.0 1e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KEZ40819.1 - 8.1e-05 22.1 0.1 0.00018 21.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KEZ40819.1 - 0.00017 21.3 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase NAD_binding_10 PF13460.6 KEZ40819.1 - 0.00051 20.0 0.9 0.34 10.8 0.0 3.3 3 0 0 3 3 2 1 NAD(P)H-binding adh_short_C2 PF13561.6 KEZ40819.1 - 0.00067 19.3 0.1 0.0022 17.6 0.0 2.0 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase PCMT PF01135.19 KEZ40819.1 - 0.003 17.3 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 KEZ40819.1 - 0.039 13.0 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase RmlD_sub_bind PF04321.17 KEZ40819.1 - 0.069 12.2 0.0 3.7 6.6 0.0 2.7 2 0 0 2 2 2 0 RmlD substrate binding domain AMP-binding_C PF13193.6 KEZ40819.1 - 0.085 13.8 0.1 0.56 11.2 0.0 2.7 2 0 0 2 2 1 0 AMP-binding enzyme C-terminal domain RestrictionSfiI PF11487.8 KEZ40819.1 - 0.12 12.2 0.2 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Type II restriction enzyme SfiI MTS PF05175.14 KEZ40819.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_33 PF10017.9 KEZ40819.1 - 0.14 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent GFO_IDH_MocA PF01408.22 KEZ40820.1 - 7.4e-18 65.5 0.0 1.3e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KEZ40820.1 - 0.00013 22.4 0.0 0.00035 21.0 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 KEZ40821.1 - 3.6e-18 65.6 3.0 5.8e-18 65.0 2.0 1.9 2 1 0 2 2 2 1 FAD binding domain Polyketide_cyc2 PF10604.9 KEZ40821.1 - 0.095 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_3 PF01494.19 KEZ40822.1 - 6.4e-22 78.3 0.1 7.4e-21 74.8 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ40822.1 - 3.5e-06 26.5 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ40822.1 - 8.4e-06 25.9 0.0 2.9e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ40822.1 - 2.2e-05 24.9 0.0 0.028 15.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ40822.1 - 4.4e-05 23.2 0.2 0.015 14.9 0.1 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ40822.1 - 8.7e-05 21.9 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEZ40822.1 - 0.002 17.5 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KEZ40822.1 - 0.008 15.3 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KEZ40822.1 - 0.0082 15.2 0.0 0.037 13.1 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KEZ40822.1 - 0.031 13.1 0.0 22 3.8 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 KEZ40822.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEZ40822.1 - 0.15 10.8 0.0 3.8 6.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.10 KEZ40822.1 - 0.19 10.7 0.0 0.36 9.8 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase Anoctamin PF04547.12 KEZ40823.1 - 2.7e-101 339.6 7.2 3.2e-101 339.4 7.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel LptF_LptG PF03739.14 KEZ40823.1 - 0.013 14.4 1.0 0.02 13.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Pex2_Pex12 PF04757.14 KEZ40823.1 - 0.12 12.0 0.1 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region ADH_zinc_N PF00107.26 KEZ40824.1 - 2.2e-09 37.4 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ40824.1 - 0.00017 21.4 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 KEZ40825.1 - 4.2e-81 273.0 0.0 5.4e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KEZ40825.1 - 4.2e-22 78.8 0.0 7.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEZ40825.1 - 1.2e-15 58.0 0.0 2.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEZ40825.1 - 1.4e-13 51.5 0.0 3.2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DIOX_N PF14226.6 KEZ40826.1 - 1.9e-27 96.4 0.0 3.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ40826.1 - 3.1e-17 62.9 0.0 5.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AhpC-TSA_2 PF13911.6 KEZ40827.1 - 1.1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KEZ40827.1 - 0.0011 18.9 0.0 0.95 9.4 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family NCE101 PF11654.8 KEZ40828.1 - 0.015 15.0 0.4 0.29 10.9 0.0 2.9 3 0 0 3 3 3 0 Non-classical export protein 1 SSP160 PF06933.11 KEZ40828.1 - 1.4 7.0 11.5 1.9 6.6 11.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FR47 PF08445.10 KEZ40829.1 - 3.4e-05 23.7 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KEZ40829.1 - 0.008 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ABC2_membrane PF01061.24 KEZ40831.1 - 8.5e-69 231.2 53.1 3.7e-38 131.1 21.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ40831.1 - 7.9e-35 120.4 0.0 2e-17 64.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KEZ40831.1 - 4.6e-32 109.8 3.1 1.4e-26 92.2 0.0 3.9 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KEZ40831.1 - 1.7e-13 50.9 0.0 4.1e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KEZ40831.1 - 4.2e-08 32.7 30.8 3.8e-05 23.0 8.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KEZ40831.1 - 1.5e-06 28.3 0.2 0.00027 20.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KEZ40831.1 - 1.7e-05 25.4 0.1 0.0044 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEZ40831.1 - 4.2e-05 23.2 0.0 0.00024 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ40831.1 - 4.5e-05 23.9 0.1 0.01 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KEZ40831.1 - 0.00025 20.6 0.0 0.093 12.2 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KEZ40831.1 - 0.00045 20.7 0.8 2.1 8.8 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KEZ40831.1 - 0.00048 19.8 0.5 0.042 13.6 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KEZ40831.1 - 0.0031 17.7 0.1 0.2 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEZ40831.1 - 0.0034 17.2 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEZ40831.1 - 0.0046 16.7 0.1 0.86 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEZ40831.1 - 0.01 16.3 0.3 2.8 8.4 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ40831.1 - 0.019 15.2 0.4 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEZ40831.1 - 0.019 14.9 0.9 2.7 7.9 0.3 2.9 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 KEZ40831.1 - 0.12 12.8 0.1 1.9 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEZ40831.1 - 0.22 11.2 1.0 21 4.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3314 PF11771.8 KEZ40832.1 - 0.054 13.6 0.1 0.47 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) NACHT PF05729.12 KEZ40833.1 - 8.6e-09 35.5 0.1 3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ40833.1 - 1.3e-07 32.1 0.0 9.7e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ40833.1 - 2e-06 28.1 0.0 1.3e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEZ40833.1 - 0.022 15.2 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KEZ40833.1 - 0.026 14.9 0.0 0.085 13.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KEZ40833.1 - 0.035 14.7 0.1 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEZ40833.1 - 0.04 14.1 0.5 0.16 12.1 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ40833.1 - 0.079 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KEZ40833.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KEZ40833.1 - 0.12 12.9 0.0 0.54 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter CFEM PF05730.11 KEZ40834.1 - 0.0026 17.8 8.1 0.0031 17.6 8.1 1.2 1 0 0 1 1 1 1 CFEM domain Nckap1 PF09735.9 KEZ40834.1 - 0.036 12.0 0.2 0.041 11.9 0.2 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Gly_transf_sug PF04488.15 KEZ40835.1 - 5.4e-16 59.0 0.1 1.1e-14 54.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KEZ40835.1 - 0.012 14.9 0.0 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Podoplanin PF05808.11 KEZ40836.1 - 0.00013 22.1 0.3 0.00023 21.3 0.3 1.4 1 1 0 1 1 1 1 Podoplanin SKG6 PF08693.10 KEZ40836.1 - 0.0022 17.3 4.2 0.0041 16.5 4.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KEZ40836.1 - 0.022 14.7 2.8 0.041 13.8 2.8 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4690 PF15756.5 KEZ40836.1 - 0.061 13.9 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Herpes_gE PF02480.16 KEZ40836.1 - 0.071 11.9 0.0 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.13 KEZ40836.1 - 0.096 11.5 0.2 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2207 PF09972.9 KEZ40836.1 - 0.15 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 KEZ40836.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 KEZ40836.1 - 0.16 12.9 0.0 0.31 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 KEZ40836.1 - 0.23 11.2 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GFO_IDH_MocA PF01408.22 KEZ40838.1 - 3.2e-15 57.0 0.0 5.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KEZ40838.1 - 0.00051 20.7 0.0 0.00096 19.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Pyridoxal_deC PF00282.19 KEZ40839.1 - 5.1e-25 88.0 0.0 7.2e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KEZ40839.1 - 0.00025 20.4 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase adh_short_C2 PF13561.6 KEZ40840.1 - 1.5e-64 217.8 0.3 1.7e-64 217.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ40840.1 - 4.5e-42 143.7 0.1 5.3e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ40840.1 - 2.5e-16 60.1 0.1 3.5e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NusB PF01029.18 KEZ40840.1 - 0.17 12.1 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 NusB family Peptidase_C97 PF05903.14 KEZ40841.1 - 1e-05 25.4 0.1 1.5e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.6 KEZ40841.1 - 0.013 15.2 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) LRAT PF04970.13 KEZ40841.1 - 0.02 15.2 1.2 0.056 13.8 0.3 2.0 1 1 1 2 2 2 0 Lecithin retinol acyltransferase DUF1870 PF08965.10 KEZ40841.1 - 0.024 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) HET PF06985.11 KEZ40842.1 - 4.1e-35 121.3 0.1 6.2e-35 120.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KEZ40842.1 - 4.1e-33 114.8 52.3 7.9e-33 113.8 52.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ40842.1 - 1.6e-15 57.0 10.2 1.6e-15 57.0 10.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ40842.1 - 1.7e-14 53.2 25.3 2.5e-14 52.7 25.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEZ40842.1 - 0.12 10.6 16.8 0.0076 14.6 6.2 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pam17 PF08566.10 KEZ40842.1 - 2.4 8.0 6.5 0.42 10.4 0.2 2.9 4 0 0 4 4 4 0 Mitochondrial import protein Pam17 Esterase_phd PF10503.9 KEZ40843.1 - 1.6e-21 76.9 0.1 2.1e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ40843.1 - 1.3e-11 44.4 0.7 1.9e-11 43.8 0.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KEZ40843.1 - 1.4e-07 30.8 0.5 2.1e-07 30.2 0.5 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ40843.1 - 0.00064 19.6 0.0 0.00092 19.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FA_desaturase PF00487.24 KEZ40844.1 - 4.9e-24 85.6 31.1 4.9e-24 85.6 31.1 1.8 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KEZ40844.1 - 1.9e-05 24.9 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF3767 PF12597.8 KEZ40844.1 - 0.15 11.9 0.1 0.61 9.9 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3767) DUF1349 PF07081.11 KEZ40845.1 - 3.5e-19 69.2 0.0 8.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) AltA1 PF16541.5 KEZ40845.1 - 2.4e-06 28.4 2.1 0.0006 20.6 0.0 2.9 2 0 0 2 2 2 2 Alternaria alternata allergen 1 Aldedh PF00171.22 KEZ40846.1 - 7.4e-143 476.4 0.9 5.7e-115 384.5 0.6 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Zn_clus PF00172.18 KEZ40847.1 - 8.9e-08 32.1 10.4 1.5e-07 31.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UbiD PF01977.16 KEZ40848.1 - 5.7e-108 361.4 0.0 8.7e-108 360.8 0.0 1.3 2 0 0 2 2 2 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase TPP_enzyme_N PF02776.18 KEZ40849.1 - 9.6e-34 116.5 0.1 2.1e-32 112.1 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEZ40849.1 - 2e-13 50.4 0.1 4e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ40849.1 - 1.3e-09 37.9 0.0 2.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MFS_1 PF07690.16 KEZ40850.1 - 1.9e-29 102.7 30.0 6.3e-29 101.0 29.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Cu_amine_oxid PF01179.20 KEZ40851.1 - 2.3e-121 405.5 0.0 3.5e-97 325.9 0.0 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KEZ40851.1 - 1.8e-07 31.3 0.2 3.8e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KEZ40851.1 - 0.0019 18.6 0.0 0.0066 16.8 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain CtsR PF05848.11 KEZ40851.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 CtsR N-terminal HTH domain FAD_binding_4 PF01565.23 KEZ40852.1 - 1.1e-20 73.8 0.2 1.6e-20 73.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain AA_permease_2 PF13520.6 KEZ40853.1 - 1.3e-54 185.7 30.5 1.8e-54 185.2 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ40853.1 - 2.2e-22 79.3 26.0 2.8e-22 79.0 26.0 1.0 1 0 0 1 1 1 1 Amino acid permease Herpes_LMP1 PF05297.11 KEZ40853.1 - 8.3 5.5 7.0 2.1 7.5 0.5 2.3 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) FMN_dh PF01070.18 KEZ40854.1 - 1.1e-107 360.0 0.4 1.4e-107 359.8 0.4 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEZ40854.1 - 1.9e-16 60.0 0.0 3.5e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KEZ40854.1 - 1.6e-06 27.5 0.2 2.8e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 KEZ40854.1 - 0.00025 20.5 1.3 0.00034 20.1 0.8 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KEZ40854.1 - 0.00058 19.0 0.3 0.00058 19.0 0.3 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KEZ40854.1 - 0.0062 15.9 1.8 0.53 9.6 0.2 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Aldedh PF00171.22 KEZ40855.1 - 1.6e-129 432.5 0.1 1.9e-129 432.2 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ40855.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) ATP-synt_C PF00137.21 KEZ40856.1 - 6.9e-13 48.7 11.0 6.9e-13 48.7 11.0 1.7 2 0 0 2 2 2 1 ATP synthase subunit C ketoacyl-synt PF00109.26 KEZ40857.1 - 1.8e-55 188.3 0.0 4.1e-55 187.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ40857.1 - 4.4e-50 170.1 0.3 1.1e-49 168.8 0.3 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KEZ40857.1 - 3.9e-41 141.2 0.1 7e-41 140.4 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEZ40857.1 - 1.7e-32 113.2 0.0 5.5e-21 75.4 0.0 2.4 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEZ40857.1 - 4.5e-24 84.7 0.0 1.2e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KEZ40857.1 - 2.7e-16 60.1 0.0 6.8e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEZ40857.1 - 1.4e-13 51.0 0.0 6.3e-13 48.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KEZ40857.1 - 1.4e-10 41.7 0.0 7.1e-10 39.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ40857.1 - 1.6e-10 41.1 0.0 1.5e-09 37.9 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40857.1 - 4.3e-10 39.6 0.0 9.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40857.1 - 1.6e-09 38.3 0.0 5.3e-09 36.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KEZ40857.1 - 2.5e-08 35.1 0.0 1.1e-06 29.7 0.0 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KEZ40857.1 - 3.6e-08 33.6 0.0 9.5e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 KEZ40857.1 - 3.7e-08 33.1 0.0 9.1e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ACP_syn_III PF08545.10 KEZ40857.1 - 0.00068 19.4 0.2 0.0019 18.0 0.2 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 KEZ40857.1 - 0.00098 18.7 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 KEZ40857.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KEZ40857.1 - 0.0018 17.7 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family KAsynt_C_assoc PF16197.5 KEZ40857.1 - 0.0025 18.3 0.0 0.0088 16.5 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_16 PF10294.9 KEZ40857.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_28 PF02636.17 KEZ40857.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Aldedh PF00171.22 KEZ40859.1 - 3.1e-171 570.0 0.0 4.5e-171 569.4 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.8 KEZ40860.1 - 3.7e-21 75.4 0.2 6.5e-21 74.6 0.2 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40860.1 - 4.9e-10 39.4 8.7 1e-09 38.3 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.20 KEZ40861.1 - 1.6e-153 511.5 0.0 2e-153 511.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KEZ40861.1 - 6.5e-22 77.8 0.0 1.6e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KEZ40861.1 - 4.8e-14 52.3 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4105 PF13387.6 KEZ40861.1 - 0.099 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) AAA PF00004.29 KEZ40862.1 - 4.1e-08 33.7 0.3 3.1e-07 30.9 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEZ40862.1 - 1.5e-05 25.0 0.1 0.003 17.5 0.0 3.0 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 KEZ40862.1 - 5.5e-05 23.6 0.2 0.00018 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ40862.1 - 0.0021 18.3 0.1 0.011 16.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEZ40862.1 - 0.023 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KEZ40862.1 - 0.047 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 KEZ40862.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KEZ40862.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 KEZ40862.1 - 0.078 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KEZ40862.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ40862.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Utp8 PF10395.9 KEZ40863.1 - 9.6e-07 27.7 0.1 3.8e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 Utp8 family PTCB-BRCT PF12738.7 KEZ40865.1 - 4.1e-44 148.4 0.2 2.1e-21 75.6 0.0 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KEZ40865.1 - 1.4e-36 124.7 0.0 1.7e-13 50.7 0.0 4.4 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEZ40865.1 - 1.5e-18 67.0 0.0 4.4e-06 27.0 0.0 4.1 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KEZ40865.1 - 1.2e-05 25.5 0.1 0.32 11.3 0.0 3.7 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KEZ40865.1 - 1.7e-05 24.6 0.0 0.0074 16.2 0.0 3.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KEZ40865.1 - 0.0026 17.8 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain OHCU_decarbox PF09349.10 KEZ40866.1 - 7e-45 153.3 0.0 8.1e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.11 KEZ40867.1 - 1e-28 99.1 1.0 1e-28 99.1 1.0 1.8 3 0 0 3 3 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KEZ40867.1 - 1.5e-13 50.8 0.0 0.085 13.2 0.0 6.0 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEZ40867.1 - 6e-11 42.7 0.2 0.055 14.4 0.0 5.5 6 0 0 6 6 5 2 WD domain, G-beta repeat eIF2A PF08662.11 KEZ40867.1 - 0.00024 21.0 0.0 0.0079 16.1 0.0 2.3 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 KEZ40867.1 - 0.0034 16.5 0.4 0.029 13.4 0.0 2.3 2 1 1 3 3 3 1 VID27 C-terminal WD40-like domain V_ATPase_I_N PF18670.1 KEZ40867.1 - 0.0038 17.6 0.5 0.04 14.3 0.3 2.3 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain U-box PF04564.15 KEZ40867.1 - 0.006 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KEZ40867.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CheZ PF04344.13 KEZ40867.1 - 0.11 12.5 0.3 0.16 11.9 0.3 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Sun2_CC2 PF18580.1 KEZ40867.1 - 0.11 12.8 0.3 6.7 7.0 0.1 2.9 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 MazG-like PF12643.7 KEZ40867.1 - 0.18 12.1 0.1 0.86 9.9 0.0 2.1 2 0 0 2 2 2 0 MazG-like family LMP PF04778.12 KEZ40867.1 - 0.25 11.2 0.6 5.5 6.9 0.1 2.2 1 1 1 2 2 2 0 LMP repeated region Apolipoprotein PF01442.18 KEZ40867.1 - 0.74 9.7 5.5 3.5 7.5 5.3 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Prok-RING_4 PF14447.6 KEZ40868.1 - 0.0012 18.7 1.9 0.0032 17.3 0.3 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEZ40868.1 - 0.0016 18.5 0.9 0.0041 17.1 0.9 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEZ40868.1 - 0.005 16.8 4.4 0.015 15.2 4.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEZ40868.1 - 0.0063 16.3 0.5 0.0063 16.3 0.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KEZ40868.1 - 0.049 13.8 1.7 0.09 12.9 0.3 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KEZ40868.1 - 0.12 12.7 3.4 0.13 12.6 0.8 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 KEZ40868.1 - 0.26 11.2 2.8 0.69 9.8 2.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TraQ PF09679.10 KEZ40869.1 - 0.031 14.2 0.1 0.081 12.8 0.1 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Aldo_ket_red PF00248.21 KEZ40870.1 - 1.5e-36 126.2 0.0 2.3e-27 96.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family LUD_dom PF02589.15 KEZ40870.1 - 0.17 11.6 0.0 1.1 9.0 0.0 2.0 1 1 1 2 2 2 0 LUD domain WD40 PF00400.32 KEZ40871.1 - 4.6e-29 100.0 1.1 6.9e-06 26.7 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ40871.1 - 3.3e-05 24.1 0.0 1.9 8.8 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KEZ40871.1 - 0.14 10.1 0.0 0.24 9.4 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Ge1_WD40 PF16529.5 KEZ40871.1 - 0.16 10.9 0.1 11 4.9 0.0 3.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Zn_Tnp_IS1595 PF12760.7 KEZ40871.1 - 0.23 11.4 1.2 0.5 10.4 1.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 KEZ40871.1 - 0.26 11.2 0.7 0.63 10.0 0.7 1.7 1 0 0 1 1 1 0 Nudix N-terminal WD40 PF00400.32 KEZ40872.1 - 1.2e-14 54.5 11.6 1.3e-06 29.0 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KEZ40872.1 - 1.3e-14 54.1 0.0 4.9e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KEZ40872.1 - 8.3e-10 38.8 1.4 0.0031 17.8 0.1 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3246 PF11596.8 KEZ40872.1 - 0.3 10.5 5.8 0.049 13.1 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Glyco_hydro_3 PF00933.21 KEZ40873.1 - 0.099 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain HNH_2 PF13391.6 KEZ40877.1 - 0.00016 21.7 0.0 0.00094 19.3 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease CorA PF01544.18 KEZ40878.1 - 5.3e-15 55.5 0.1 9.8e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Virul_fac_BrkB PF03631.15 KEZ40878.1 - 0.012 15.3 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Virulence factor BrkB EMP70 PF02990.16 KEZ40878.1 - 0.063 11.9 0.8 0.096 11.3 0.8 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Phage_holin_3_6 PF07332.11 KEZ40878.1 - 0.12 12.5 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2207 PF09972.9 KEZ40878.1 - 0.12 11.1 0.2 0.17 10.6 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.18 KEZ40879.1 - 5.6e-16 58.4 0.2 1e-15 57.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain YqbF PF14553.6 KEZ40879.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 YqbF, hypothetical protein domain TBCC_N PF16752.5 KEZ40880.1 - 0.0017 18.8 5.6 0.039 14.4 0.5 3.2 3 1 0 3 3 3 1 Tubulin-specific chaperone C N-terminal domain SesA PF17107.5 KEZ40880.1 - 0.01 16.0 6.7 0.019 15.1 2.0 2.4 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Occludin_ELL PF07303.13 KEZ40880.1 - 0.12 13.1 0.5 16 6.3 0.0 3.2 1 1 2 4 4 4 0 Occludin homology domain DUF16 PF01519.16 KEZ40880.1 - 0.16 12.5 2.3 0.65 10.5 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 Med9 PF07544.13 KEZ40880.1 - 0.36 11.0 3.2 7.8 6.7 0.1 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TcA_TcB_BD PF18276.1 KEZ40881.1 - 8.5e-103 343.4 0.0 1.3e-102 342.8 0.0 1.3 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 KEZ40881.1 - 5.3e-30 104.3 1.5 6.6e-30 104.0 0.1 1.9 2 0 0 2 2 2 1 Neuraminidase-like domain DUF3113 PF11310.8 KEZ40881.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) SpvB PF03534.13 KEZ40882.1 - 2.6e-102 341.9 0.2 1.2e-100 336.4 0.0 2.6 3 0 0 3 3 3 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 KEZ40882.1 - 2.6e-32 111.6 7.2 2.8e-25 88.7 0.0 6.2 3 2 3 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 KEZ40882.1 - 2.5e-28 99.0 0.0 5.1e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 KEZ40882.1 - 0.00057 20.4 17.7 0.0032 18.0 0.1 5.6 4 2 2 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS_repeat PF05593.14 KEZ40882.1 - 0.018 15.6 49.5 0.02 15.4 1.4 12.3 14 2 1 15 15 15 0 RHS Repeat GMC_oxred_N PF00732.19 KEZ40883.1 - 2.3e-55 188.1 0.0 3.1e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ40883.1 - 2.4e-33 115.7 0.0 8.6e-33 113.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ40883.1 - 7.4e-06 25.3 0.1 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KEZ40883.1 - 7.1e-05 23.0 3.6 0.00027 21.1 0.1 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ40883.1 - 0.00016 21.4 1.8 0.00049 19.8 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ40883.1 - 0.00095 18.5 0.0 0.0025 17.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ40883.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein TrkA_N PF02254.18 KEZ40883.1 - 0.0088 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 KEZ40883.1 - 0.04 13.2 1.9 0.06 12.6 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ40883.1 - 0.065 11.9 0.0 0.065 11.9 0.0 1.8 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KEZ40883.1 - 0.068 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KEZ40883.1 - 0.088 12.8 0.1 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding TFIIA PF03153.13 KEZ40883.1 - 8.3 6.3 15.0 12 5.7 15.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UDPGT PF00201.18 KEZ40884.1 - 0.098 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase CotJB PF12652.7 KEZ40884.1 - 0.19 12.0 0.2 0.19 12.0 0.2 2.2 2 1 0 2 2 2 0 CotJB protein MFS_1 PF07690.16 KEZ40885.1 - 2.8e-25 89.0 32.7 5.7e-14 51.8 9.2 2.5 2 1 1 3 3 3 3 Major Facilitator Superfamily Esterase_phd PF10503.9 KEZ40886.1 - 1.5e-13 50.8 4.4 6e-07 29.2 0.8 2.9 2 1 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ40886.1 - 7e-07 28.9 0.1 1.3e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEZ40886.1 - 0.043 13.7 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KEZ40886.1 - 0.045 13.4 0.2 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 Putative esterase DUF3176 PF11374.8 KEZ40888.1 - 5.9e-23 81.1 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MFS_1 PF07690.16 KEZ40889.1 - 3.7e-07 29.4 19.9 1.1e-06 27.9 19.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1127 PF06568.11 KEZ40889.1 - 0.086 12.6 0.7 0.42 10.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Polyketide_cyc2 PF10604.9 KEZ40890.1 - 6.1e-06 26.6 1.0 7.5e-06 26.3 1.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Arylsulfotran_2 PF14269.6 KEZ40892.1 - 5.4e-72 242.7 0.9 7e-72 242.3 0.9 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KEZ40892.1 - 8.8e-17 61.1 0.3 9.6e-16 57.7 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 KEZ40893.1 - 7.6e-43 146.8 43.7 7.6e-43 146.8 43.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Zw10 PF06248.13 KEZ40893.1 - 0.21 10.1 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 FA_hydroxylase PF04116.13 KEZ40894.1 - 4.4e-25 88.6 24.0 4.2e-24 85.4 22.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 KEZ40895.1 - 4.8e-33 114.5 33.3 4.8e-33 114.5 33.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_75 PF07335.11 KEZ40896.1 - 2.5e-64 216.5 1.7 1.7e-63 213.8 0.7 2.0 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 PhoPQ_related PF10142.9 KEZ40896.1 - 0.06 12.0 0.0 0.085 11.5 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein MFS_1 PF07690.16 KEZ40897.1 - 0.00033 19.7 16.9 0.035 13.0 3.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 KEZ40897.1 - 0.77 10.0 3.1 2.5 8.4 1.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ifi-6-16 PF06140.13 KEZ40897.1 - 1.8 8.6 4.6 18 5.3 0.1 2.8 3 0 0 3 3 3 0 Interferon-induced 6-16 family AtuA PF07287.11 KEZ40898.1 - 6.6e-108 360.6 0.1 8.4e-108 360.2 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Carboxyl_trans PF01039.22 KEZ40899.1 - 9.4e-117 390.6 0.0 1.1e-116 390.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KEZ40900.1 - 1.1e-66 224.4 0.0 2.1e-66 223.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEZ40900.1 - 2e-43 147.4 0.1 4.3e-43 146.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ40900.1 - 3.5e-31 107.5 0.0 9.3e-31 106.1 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEZ40900.1 - 5.6e-11 42.1 0.7 1.9e-10 40.4 0.7 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KEZ40900.1 - 2.5e-10 40.6 0.0 5.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEZ40900.1 - 1.1e-08 34.9 0.0 4.3e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEZ40900.1 - 2.9e-08 33.5 0.1 3e-07 30.1 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KEZ40900.1 - 0.0005 19.8 0.1 0.0018 18.1 0.1 2.0 1 1 0 1 1 1 1 Biotin-lipoyl like MinE PF03776.14 KEZ40900.1 - 0.05 13.6 0.8 0.67 10.0 0.1 2.9 3 0 0 3 3 3 0 Septum formation topological specificity factor MinE FAF PF11250.8 KEZ40900.1 - 0.18 12.1 0.3 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 Fantastic Four meristem regulator ECH_1 PF00378.20 KEZ40901.1 - 4.2e-35 121.3 0.0 5.1e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ40901.1 - 2.8e-10 40.2 0.0 3.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 KEZ40902.1 - 1.8e-23 82.9 0.2 2.4e-23 82.4 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ40902.1 - 6e-12 46.4 0.0 9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rhabdo_glycop PF00974.18 KEZ40902.1 - 0.0053 15.3 0.0 0.0064 15.0 0.0 1.0 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Acyl-CoA_dh_1 PF00441.24 KEZ40903.1 - 1.2e-28 100.3 0.3 1.7e-28 99.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ40903.1 - 1.2e-22 79.9 0.1 2e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEZ40903.1 - 5.8e-18 65.6 0.0 1.6e-17 64.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEZ40903.1 - 0.024 14.9 0.1 0.043 14.1 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SET PF00856.28 KEZ40904.1 - 2.6e-09 37.7 0.0 4.7e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 SET domain Asparaginase_2 PF01112.18 KEZ40905.1 - 5.8e-59 199.6 0.6 5e-28 98.0 0.0 4.1 3 1 0 3 3 3 3 Asparaginase PHO4 PF01384.20 KEZ40906.1 - 0.0019 17.3 0.1 0.0032 16.6 0.1 1.6 1 1 0 1 1 1 1 Phosphate transporter family FAD_binding_4 PF01565.23 KEZ40907.1 - 1.5e-23 83.1 0.4 3.2e-23 82.0 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ40907.1 - 2.8e-07 30.5 0.0 5.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_114 PF03537.13 KEZ40908.1 - 1.7e-26 93.0 0.4 2e-19 69.8 0.0 2.2 1 1 1 2 2 2 2 Glycoside-hydrolase family GH114 ETRAMP PF09716.10 KEZ40908.1 - 0.17 12.0 0.1 0.46 10.6 0.1 1.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_23 PF13489.6 KEZ40910.1 - 1.3e-09 38.1 0.0 2e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ40910.1 - 2.6e-06 28.0 0.0 7.5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ40910.1 - 4.1e-06 27.4 0.0 1.8e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ40910.1 - 0.00019 21.2 0.0 0.0029 17.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ40910.1 - 0.00031 21.4 0.0 0.00088 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ40910.1 - 0.03 13.7 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AHSP PF09236.10 KEZ40910.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Fungal_trans PF04082.18 KEZ40911.1 - 5.7e-15 55.1 0.1 8.6e-15 54.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40911.1 - 1.1e-06 28.7 11.1 2.4e-06 27.6 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Btz PF09405.10 KEZ40911.1 - 0.027 14.7 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding CdiI_3 PF18616.1 KEZ40911.1 - 0.033 14.0 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 CDI immunity proteins Sugar_tr PF00083.24 KEZ40912.1 - 8.5e-63 212.8 10.1 2e-39 135.8 0.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ40912.1 - 0.0052 15.7 20.0 0.82 8.5 20.3 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Adeno_E3_CR2 PF02439.15 KEZ40913.1 - 0.017 14.8 0.4 0.041 13.6 0.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Protocadherin PF08374.11 KEZ40913.1 - 0.063 13.3 0.0 0.097 12.6 0.0 1.2 1 0 0 1 1 1 0 Protocadherin End_tail_spike PF12219.8 KEZ40914.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase zf-C2H2 PF00096.26 KEZ40915.1 - 0.017 15.5 0.6 0.017 15.5 0.6 4.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-CHCC PF10276.9 KEZ40915.1 - 0.062 13.4 7.3 1.5 8.9 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.15 KEZ40915.1 - 9.1 6.4 12.7 3.5 7.7 1.1 3.8 3 0 0 3 3 3 0 BED zinc finger DSPc PF00782.20 KEZ40916.1 - 2.4e-10 40.4 0.0 2.3e-05 24.2 0.0 3.1 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KEZ40916.1 - 0.23 11.8 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Vfa1 PF08432.10 KEZ40917.1 - 4.3e-40 138.0 25.7 5.4e-40 137.6 25.7 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 KEZ40917.1 - 0.015 14.7 15.4 0.017 14.6 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SRP-alpha_N PF04086.13 KEZ40917.1 - 0.11 12.4 22.4 0.13 12.2 22.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SpoIIIAH PF12685.7 KEZ40917.1 - 0.14 12.0 14.1 0.19 11.5 14.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein TP53IP5 PF15331.6 KEZ40917.1 - 0.25 11.5 17.6 0.31 11.2 17.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CDC45 PF02724.14 KEZ40917.1 - 0.33 9.2 25.8 0.4 8.9 25.8 1.0 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 KEZ40917.1 - 0.58 9.4 14.0 0.72 9.1 14.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 SLC12 PF03522.15 KEZ40917.1 - 0.66 8.9 14.0 0.73 8.8 14.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NARP1 PF12569.8 KEZ40917.1 - 0.83 8.5 21.9 0.92 8.3 21.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RRN3 PF05327.11 KEZ40917.1 - 1.1 7.7 13.2 1.2 7.6 13.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Serinc PF03348.15 KEZ40917.1 - 1.5 7.7 3.9 2 7.2 3.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF908 PF06012.12 KEZ40917.1 - 1.7 8.0 10.8 2 7.7 10.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DDHD PF02862.17 KEZ40917.1 - 1.9 8.6 8.8 2.4 8.3 8.8 1.2 1 0 0 1 1 1 0 DDHD domain Hydin_ADK PF17213.3 KEZ40917.1 - 2.3 8.4 8.2 2.8 8.2 8.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain IHABP4_N PF16174.5 KEZ40917.1 - 2.4 8.8 32.3 1.6 9.4 30.9 1.3 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RR_TM4-6 PF06459.12 KEZ40917.1 - 2.7 7.7 22.3 3.9 7.2 22.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 KEZ40917.1 - 3 6.5 20.7 3.4 6.4 20.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 KEZ40917.1 - 3.1 6.9 11.3 3.6 6.7 11.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 KEZ40917.1 - 3.1 4.8 7.2 3.5 4.6 7.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Paramyxo_ncap PF00973.19 KEZ40917.1 - 3.2 6.5 10.3 3.9 6.3 10.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein V_ATPase_I PF01496.19 KEZ40917.1 - 3.4 5.5 11.4 4 5.2 11.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCM_bind PF09739.9 KEZ40917.1 - 3.9 5.8 14.6 4.6 5.6 14.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 KEZ40917.1 - 4 6.1 16.3 4.4 6.0 16.3 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 KEZ40917.1 - 4.2 6.0 14.0 4.9 5.8 14.0 1.1 1 0 0 1 1 1 0 Raftlin SID-1_RNA_chan PF13965.6 KEZ40917.1 - 4.6 5.5 4.0 6.1 5.1 4.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 KEZ40917.1 - 6.3 4.8 17.4 7.5 4.5 17.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.8 KEZ40917.1 - 6.5 6.8 11.8 8 6.5 11.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CLN3 PF02487.17 KEZ40917.1 - 7.8 5.4 5.4 8.3 5.3 5.4 1.3 1 0 0 1 1 1 0 CLN3 protein DUF913 PF06025.12 KEZ40917.1 - 9.2 5.1 11.4 11 4.8 11.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Membralin PF09746.9 KEZ40917.1 - 9.7 5.1 7.0 11 5.0 7.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Rtt106 PF08512.12 KEZ40918.1 - 1.3e-30 105.6 0.0 1.9e-29 101.9 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KEZ40918.1 - 0.00086 19.3 0.0 0.0095 15.9 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain DUF4659 PF15558.6 KEZ40918.1 - 0.094 11.6 6.4 0.13 11.1 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) Nop14 PF04147.12 KEZ40918.1 - 4.9 5.2 32.2 6.7 4.8 32.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ldh_1_N PF00056.23 KEZ40919.1 - 1.7e-33 115.7 0.2 2.7e-33 115.0 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KEZ40919.1 - 2.8e-16 59.9 0.0 7.1e-16 58.6 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 KEZ40919.1 - 0.06 12.9 0.4 0.12 11.9 0.3 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KEZ40919.1 - 0.11 13.1 0.4 0.26 11.9 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KEZ40919.1 - 0.18 11.2 0.5 0.66 9.3 0.1 2.0 3 0 0 3 3 3 0 ThiF family PT PF04886.12 KEZ40920.1 - 3e-08 33.1 20.6 3e-08 33.1 20.6 6.0 2 1 3 5 5 5 2 PT repeat SLATT_5 PF18160.1 KEZ40921.1 - 0.2 11.0 1.5 0.42 9.9 0.1 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Lactamase_B_2 PF12706.7 KEZ40922.1 - 1.3e-06 28.1 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KEZ40922.1 - 1.5e-05 25.1 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KEZ40922.1 - 0.012 15.6 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily FAD_binding_3 PF01494.19 KEZ40923.1 - 1.1e-79 268.3 0.0 1.5e-79 267.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ40923.1 - 0.00087 19.0 0.0 0.046 13.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ40923.1 - 0.026 13.8 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ40923.1 - 0.041 14.4 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ40923.1 - 0.045 12.8 0.1 0.079 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KEZ40923.1 - 0.047 13.9 1.6 0.12 12.7 1.6 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ40923.1 - 0.18 11.0 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 Thi4 family ADH_N PF08240.12 KEZ40924.1 - 2.9e-12 46.4 2.7 9.6e-12 44.8 2.2 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ40924.1 - 2.9e-12 46.7 0.1 8.8e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KEZ40924.1 - 5.1e-06 26.3 0.1 1.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 KEZ40924.1 - 0.0033 16.8 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PglD_N PF17836.1 KEZ40924.1 - 0.13 13.0 0.1 2.6 8.8 0.0 2.3 2 0 0 2 2 2 0 PglD N-terminal domain PrmA PF06325.13 KEZ40924.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NYN PF01936.18 KEZ40925.1 - 3.6e-08 34.0 0.0 4.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NYN domain H_lectin PF09458.10 KEZ40925.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 H-type lectin domain PH_10 PF15411.6 KEZ40928.1 - 3.5e-40 137.1 0.5 6.2e-40 136.3 0.5 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KEZ40928.1 - 4.6e-30 105.2 0.1 9.3e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 KEZ40928.1 - 4.7e-26 90.9 0.0 9.6e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 KEZ40928.1 - 2.2e-07 30.7 0.0 4.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 KEZ40928.1 - 0.099 13.2 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 PH domain DUF5645 PF18713.1 KEZ40928.1 - 0.11 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) Mob1_phocein PF03637.17 KEZ40929.1 - 1.4e-41 142.3 0.0 2.1e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family WD40 PF00400.32 KEZ40930.1 - 3.6e-25 87.7 6.5 0.001 19.9 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KEZ40930.1 - 1.2e-12 47.5 1.9 2.7e-12 46.4 1.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ40930.1 - 8.6e-08 31.9 1.5 2.2e-07 30.6 1.0 2.0 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KEZ40930.1 - 6.2e-06 26.4 0.3 0.49 10.7 0.0 3.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain MgtE_N PF03448.17 KEZ40930.1 - 0.047 14.3 0.0 0.16 12.6 0.0 1.8 2 0 0 2 2 2 0 MgtE intracellular N domain Nup160 PF11715.8 KEZ40930.1 - 0.063 11.9 0.0 2.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 F-box_4 PF15966.5 KEZ40930.1 - 0.19 11.6 0.4 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 F-box Beta-lactamase PF00144.24 KEZ40931.1 - 1.8e-50 172.1 0.1 2.3e-50 171.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KEZ40931.1 - 0.018 14.6 0.1 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase enzyme family DUF3425 PF11905.8 KEZ40932.1 - 1.6e-19 70.1 0.1 3.2e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ADH_N PF08240.12 KEZ40933.1 - 2e-23 82.4 5.7 3e-23 81.8 5.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ40933.1 - 1.9e-17 63.4 0.0 3.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ40933.1 - 4.7e-07 30.9 0.0 7.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEZ40933.1 - 0.0056 16.0 0.1 0.0095 15.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KEZ40933.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease PF00324.21 KEZ40935.1 - 1.2e-136 456.2 33.8 1.3e-136 456.0 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ40935.1 - 6.9e-41 140.5 36.1 9.5e-41 140.0 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease CFEM PF05730.11 KEZ40936.1 - 8.8e-10 38.5 11.5 1.3e-09 38.0 11.5 1.2 1 0 0 1 1 1 1 CFEM domain Cnn_1N PF07989.11 KEZ40937.1 - 1.7e-10 40.9 7.2 4.7e-10 39.5 7.2 1.9 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 SKA1 PF07160.12 KEZ40937.1 - 0.0048 16.8 0.8 0.0048 16.8 0.8 2.2 3 0 0 3 3 3 1 Spindle and kinetochore-associated protein 1 bZIP_1 PF00170.21 KEZ40937.1 - 4.2 7.5 11.0 6.6 6.9 2.7 3.1 2 1 1 3 3 3 0 bZIP transcription factor PRKCSH PF07915.13 KEZ40938.1 - 8.2e-19 68.4 1.1 2e-18 67.2 1.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KEZ40938.1 - 0.00066 19.4 0.0 0.071 12.8 0.0 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein CCDC53 PF10152.9 KEZ40938.1 - 0.01 16.3 1.4 0.019 15.4 1.4 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4569 PF15133.6 KEZ40938.1 - 0.04 13.6 2.7 0.086 12.5 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Suf PF05843.14 KEZ40938.1 - 0.19 11.7 2.3 0.25 11.3 2.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Roughex PF06020.11 KEZ40938.1 - 0.89 8.6 3.9 1.7 7.7 3.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF4834 PF16118.5 KEZ40938.1 - 1.2 10.1 4.9 3.3 8.7 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 KEZ40938.1 - 1.3 8.6 11.9 2.2 7.8 11.9 1.3 1 0 0 1 1 1 0 Spt20 family KH_1 PF00013.29 KEZ40940.1 - 5.5e-46 154.2 21.4 7.1e-16 57.8 0.6 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KEZ40940.1 - 1.4e-09 37.6 8.7 0.012 15.4 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KEZ40940.1 - 6.6e-09 35.5 7.1 0.042 13.7 0.1 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KEZ40940.1 - 0.0017 18.3 0.0 3 7.9 0.0 3.0 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 KEZ40940.1 - 0.0081 16.2 8.8 1.2 9.2 2.2 3.8 3 1 0 3 3 3 2 NusA-like KH domain DEAD PF00270.29 KEZ40941.1 - 8.9e-48 162.4 0.0 1.4e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40941.1 - 4.1e-24 85.1 0.0 3.6e-23 82.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEZ40941.1 - 8.7e-20 70.7 0.2 1.7e-19 69.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEZ40941.1 - 9.6e-05 22.4 0.0 9.6e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KEZ40941.1 - 0.006 16.3 0.0 0.059 13.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ40941.1 - 0.14 12.1 0.4 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain CDC45 PF02724.14 KEZ40941.1 - 0.21 9.8 17.6 0.3 9.3 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KEZ40941.1 - 0.37 10.2 23.9 0.57 9.6 23.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEZ40941.1 - 0.64 8.2 23.4 0.86 7.7 23.4 1.1 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 KEZ40941.1 - 1 9.3 29.1 0.12 12.4 24.8 1.6 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) PNISR PF15996.5 KEZ40941.1 - 4 7.7 15.6 6.6 7.0 15.6 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CMS1 PF14617.6 KEZ40941.1 - 6 6.1 7.3 0.63 9.3 0.1 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit 6PF2K PF01591.18 KEZ40942.1 - 1.4e-80 269.8 0.0 2e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KEZ40942.1 - 5.2e-34 117.6 0.0 8.9e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KEZ40942.1 - 2.3e-06 27.8 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEZ40942.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Asp PF00026.23 KEZ40943.1 - 2e-38 132.6 0.0 3.3e-38 131.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KEZ40943.1 - 0.00011 22.8 0.0 0.29 11.8 0.0 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KEZ40943.1 - 0.0092 15.8 0.1 0.058 13.2 0.1 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF3337 PF11816.8 KEZ40944.1 - 1.2e-53 181.5 0.0 2.1e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KEZ40944.1 - 1.2e-18 67.1 12.6 2.8e-05 24.8 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ40944.1 - 0.0015 18.8 0.2 0.083 13.2 0.0 3.6 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ40944.1 - 0.035 12.7 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ATP_bind_3 PF01171.20 KEZ40945.1 - 8.9e-38 129.9 0.0 2.2e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 PP-loop family DUF4097 PF13349.6 KEZ40946.1 - 0.00049 19.5 2.1 0.34 10.2 0.2 3.0 2 1 0 2 2 2 2 Putative adhesin Mito_carr PF00153.27 KEZ40947.1 - 6.6e-65 215.1 8.0 2.6e-24 85.0 0.2 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KEZ40947.1 - 1.2e-18 67.3 0.5 3.9e-10 40.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KEZ40947.1 - 3.8e-18 63.6 6.2 1.2e-05 24.5 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 KEZ40947.1 - 4.1e-17 60.8 4.2 1.5e-05 24.2 0.6 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KEZ40947.1 - 6.7e-14 50.6 3.4 0.00053 19.7 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 KEZ40947.1 - 3.7e-09 36.3 1.2 0.00044 20.1 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KEZ40947.1 - 5.9e-08 33.0 0.0 0.00037 20.8 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SOG2 PF10428.9 KEZ40947.1 - 0.029 13.6 7.8 0.039 13.1 7.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Serine_protease PF18405.1 KEZ40947.1 - 0.04 13.1 1.9 0.59 9.2 0.0 3.1 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Miga PF10265.9 KEZ40947.1 - 0.63 9.0 5.1 0.95 8.4 5.1 1.2 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 KEZ40947.1 - 1.1 7.7 4.1 1.5 7.3 4.1 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KEZ40947.1 - 2.6 6.8 7.1 4.1 6.2 7.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cyclin_N PF00134.23 KEZ40948.1 - 3.7e-13 49.3 1.4 1.6e-11 44.1 1.0 2.4 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KEZ40948.1 - 0.0007 20.0 1.3 0.0023 18.3 0.5 2.3 2 1 0 2 2 2 1 Cyclin C-terminal domain AMIN PF11741.8 KEZ40948.1 - 0.02 15.0 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 AMIN domain TFIIB PF00382.19 KEZ40948.1 - 0.036 14.1 0.3 0.036 14.1 0.3 2.2 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF4452 PF14618.6 KEZ40949.1 - 2.4e-77 258.6 14.0 2.8e-77 258.4 14.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) AAA_12 PF13087.6 KEZ40950.1 - 0.00052 19.7 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Myosin_N PF02736.19 KEZ40950.1 - 0.13 12.1 0.3 0.31 10.9 0.3 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain SNARE PF05739.19 KEZ40952.1 - 5.5e-09 35.9 0.6 5.5e-09 35.9 0.6 1.7 2 0 0 2 2 2 1 SNARE domain TBCA PF02970.16 KEZ40952.1 - 0.033 14.5 1.2 0.077 13.3 0.2 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A Halogen_Hydrol PF10112.9 KEZ40952.1 - 0.19 11.7 0.7 0.36 10.8 0.1 1.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SlyX PF04102.12 KEZ40952.1 - 1.1 9.9 9.3 7.4 7.3 0.7 4.0 2 2 2 4 4 4 0 SlyX Trimer_CC PF08954.11 KEZ40952.1 - 1.2 8.7 6.6 14 5.4 0.1 3.5 3 1 0 3 3 3 0 Trimerisation motif PilJ PF13675.6 KEZ40952.1 - 1.3 9.1 10.0 0.4 10.7 0.2 3.0 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term ANAPC4_WD40 PF12894.7 KEZ40953.1 - 0.00027 21.2 0.5 0.096 13.0 0.0 3.6 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEZ40953.1 - 0.037 14.9 6.8 0.057 14.3 0.1 4.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Vps39_1 PF10366.9 KEZ40954.1 - 3.8e-35 120.4 0.5 6.8e-34 116.4 0.0 3.4 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KEZ40954.1 - 7.4e-14 52.1 0.0 3.3e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KEZ40954.1 - 7.8e-12 45.4 0.0 0.00011 21.9 0.0 2.6 2 1 0 2 2 2 2 CNH domain Clathrin PF00637.20 KEZ40954.1 - 0.00031 20.6 1.2 0.0075 16.1 0.2 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_2 PF07719.17 KEZ40954.1 - 0.038 14.1 3.1 35 4.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ40954.1 - 0.054 13.3 8.7 1.1 9.2 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ40954.1 - 0.069 13.4 2.9 20 5.5 0.3 3.7 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KEZ40954.1 - 0.23 11.8 4.5 40 4.6 0.1 4.4 3 2 1 5 5 5 0 Tetratricopeptide repeat LIM_bind PF01803.16 KEZ40955.1 - 2.6e-65 220.3 0.0 2.6e-65 220.3 0.0 4.1 3 1 0 3 3 3 1 LIM-domain binding protein SPX PF03105.19 KEZ40955.1 - 6 6.7 14.1 4.2 7.2 0.9 2.4 2 0 0 2 2 2 0 SPX domain Aminotran_1_2 PF00155.21 KEZ40956.1 - 3.6e-90 302.8 0.0 4.1e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Lipase_GDSL_2 PF13472.6 KEZ40956.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family JmjC PF02373.22 KEZ40957.1 - 3.1e-11 43.7 0.1 9.6e-11 42.1 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KEZ40957.1 - 9.6e-07 29.0 10.9 9.6e-07 29.0 10.9 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KEZ40957.1 - 0.0021 17.7 0.2 0.0059 16.3 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Ribosom_S12_S23 PF00164.25 KEZ40958.1 - 1.1e-50 170.0 0.4 1.3e-50 169.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RF-1 PF00472.20 KEZ40960.1 - 0.017 15.0 0.6 0.017 15.0 0.6 5.9 6 1 1 7 7 7 0 RF-1 domain Exog_C PF18026.1 KEZ40960.1 - 0.041 13.9 7.6 0.052 13.6 0.3 4.1 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain DUF3800 PF12686.7 KEZ40960.1 - 0.08 13.6 0.1 63 4.2 0.0 4.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3800) ADK PF00406.22 KEZ40961.1 - 1.4e-58 197.3 0.0 1.9e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEZ40961.1 - 9.5e-23 81.1 0.2 1.7e-22 80.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KEZ40961.1 - 5.5e-16 58.3 0.0 1.5e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KEZ40961.1 - 0.00015 22.3 0.0 0.00031 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEZ40961.1 - 0.0031 17.7 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KEZ40961.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase TPR_12 PF13424.6 KEZ40962.1 - 7e-23 80.7 18.7 1e-09 38.5 2.8 6.8 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ40962.1 - 1.3e-17 63.0 13.2 0.00042 20.1 2.6 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ40962.1 - 5.6e-16 58.5 0.0 9.3e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 KEZ40962.1 - 1.6e-12 46.5 3.1 0.23 11.8 0.9 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ40962.1 - 1.8e-10 40.1 6.6 0.0079 16.2 0.8 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ40962.1 - 3e-07 30.1 1.7 0.0086 15.5 0.0 2.8 1 1 2 3 3 3 2 MalT-like TPR region TPR_1 PF00515.28 KEZ40962.1 - 9.2e-07 28.4 7.1 0.00013 21.6 1.2 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ40962.1 - 2.6e-06 27.1 13.8 1.6 9.0 1.8 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ40962.1 - 7.1e-05 23.2 8.0 2.6 8.6 0.1 5.8 4 1 2 6 6 6 3 Tetratricopeptide repeat ATPase PF06745.13 KEZ40962.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 KaiC TPR_17 PF13431.6 KEZ40962.1 - 0.0029 17.9 0.1 3.6 8.2 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 KEZ40962.1 - 0.023 14.9 2.0 19 5.8 0.0 4.8 5 0 0 5 5 5 0 PPR repeat AAA_16 PF13191.6 KEZ40962.1 - 0.032 14.6 0.4 0.19 12.1 0.0 2.7 2 1 0 2 2 1 0 AAA ATPase domain IstB_IS21 PF01695.17 KEZ40962.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_14 PF13428.6 KEZ40962.1 - 0.055 14.3 24.3 26 6.0 0.1 8.4 7 2 1 8 8 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KEZ40962.1 - 0.059 13.4 0.2 0.66 10.1 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 KEZ40962.1 - 0.073 13.4 0.3 1.4 9.3 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat ArsA_ATPase PF02374.15 KEZ40962.1 - 0.09 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_25 PF13481.6 KEZ40962.1 - 0.12 11.9 0.2 0.43 10.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KEZ40962.1 - 0.18 11.4 0.2 0.47 10.1 0.1 1.7 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain TPR_6 PF13174.6 KEZ40962.1 - 1.8 9.4 10.3 8.5 7.2 0.0 5.9 8 0 0 8 8 5 0 Tetratricopeptide repeat MitMem_reg PF13012.6 KEZ40963.1 - 2.9e-36 124.3 0.1 8e-36 122.9 0.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KEZ40963.1 - 8.8e-31 106.3 0.2 2.3e-30 105.0 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FANCI_S4 PF14678.6 KEZ40963.1 - 0.007 15.5 0.1 0.016 14.3 0.1 1.6 2 0 0 2 2 2 1 FANCI solenoid 4 tRNA_bind_2 PF13725.6 KEZ40963.1 - 0.033 13.9 5.8 0.05 13.3 5.8 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 KEZ40963.1 - 0.67 9.7 5.0 1.1 8.9 5.0 1.3 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 KEZ40963.1 - 7.6 5.6 11.1 11 5.1 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Coprogen_oxidas PF01218.18 KEZ40964.1 - 4.2e-145 482.0 0.1 4.8e-145 481.8 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF1651 PF07864.11 KEZ40964.1 - 0.028 14.7 0.1 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) Atg8 PF02991.16 KEZ40965.1 - 9.2e-51 170.4 0.2 1.1e-50 170.2 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KEZ40965.1 - 7.5e-06 26.3 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_9 PF14604.6 KEZ40965.1 - 0.16 11.9 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain Lustrin_cystein PF14625.6 KEZ40966.1 - 0.2 12.1 9.7 1.4 9.4 9.7 2.0 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain WRC PF08879.10 KEZ40967.1 - 0.32 10.7 0.1 0.32 10.7 0.1 6.8 8 1 1 9 9 9 0 WRC TPR_12 PF13424.6 KEZ40968.1 - 4.1e-11 43.0 6.7 6.4e-06 26.4 0.8 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ40968.1 - 4.3e-09 35.8 2.4 0.21 11.8 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ40968.1 - 4e-07 29.6 0.0 1.3 8.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ40968.1 - 5.2e-05 23.1 0.2 1.7 9.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ40968.1 - 0.00019 22.0 8.0 0.79 10.7 0.5 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ40968.1 - 0.0007 19.4 9.4 0.24 11.3 0.1 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ40968.1 - 0.00099 19.0 1.9 2.8 8.2 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ40968.1 - 0.0033 18.0 4.1 0.39 11.4 1.5 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ40968.1 - 0.004 17.6 0.7 0.041 14.4 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat NAT PF04768.13 KEZ40970.1 - 1.6e-41 141.8 0.0 3e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase BAR_2 PF10455.9 KEZ40971.1 - 5.4e-60 203.0 0.9 8.2e-60 202.4 0.9 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KEZ40971.1 - 1.4e-21 77.3 3.5 3.5e-20 72.7 3.5 2.0 1 1 0 1 1 1 1 BAR domain Goodbye PF17109.5 KEZ40971.1 - 0.022 15.2 0.3 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain STG PF15809.5 KEZ40971.1 - 0.072 13.2 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Simian taste bud-specific gene product family BAR_3 PF16746.5 KEZ40971.1 - 0.078 12.7 0.9 0.44 10.2 0.2 2.4 2 1 0 2 2 2 0 BAR domain of APPL family Mod_r PF07200.13 KEZ40971.1 - 0.13 12.4 3.6 0.58 10.3 0.0 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ETC_C1_NDUFA5 PF04716.14 KEZ40972.1 - 4.6e-24 84.0 2.8 8.4e-23 80.0 0.1 3.0 3 0 0 3 3 3 1 ETC complex I subunit conserved region Phage_TAC_11 PF11836.8 KEZ40972.1 - 0.035 14.2 0.2 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 WD40 PF00400.32 KEZ40973.1 - 1.3e-13 51.1 12.8 3.2e-06 27.7 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ran_BP1 PF00638.18 KEZ40974.1 - 2.2e-05 24.7 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain MIF4G PF02854.19 KEZ40975.1 - 2.3e-56 190.8 0.0 1.7e-30 106.3 0.0 3.4 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 KEZ40975.1 - 6.6e-39 133.8 10.6 3.2e-38 131.5 6.6 2.5 2 0 0 2 2 2 1 Up-frameshift suppressor 2 DEAD PF00270.29 KEZ40975.1 - 2.9e-15 56.5 0.0 5.6e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ40975.1 - 8.4e-13 48.6 0.0 1.9e-11 44.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 KEZ40975.1 - 5.2e-06 27.1 0.0 1.5e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.11 KEZ40975.1 - 0.00049 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 KEZ40975.1 - 0.0026 17.8 0.1 0.0095 15.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSP70 PF00012.20 KEZ40976.1 - 3.7e-171 570.3 3.0 8.8e-171 569.1 3.0 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ40976.1 - 3.9e-14 52.2 0.0 1.9e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KEZ40976.1 - 0.0018 18.6 0.0 2 8.9 0.0 3.1 2 1 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.28 KEZ40976.1 - 0.0091 16.1 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GTP_EFTU PF00009.27 KEZ40977.1 - 1.3e-34 119.5 0.0 4.8e-34 117.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KEZ40977.1 - 1.3e-19 70.2 0.0 4.3e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KEZ40977.1 - 2.5e-10 40.6 7.8 3e-07 30.7 0.2 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KEZ40977.1 - 1.5e-08 34.5 1.2 4.5e-08 32.9 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KEZ40977.1 - 1.2e-06 28.6 0.1 2.3e-05 24.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KEZ40977.1 - 0.00029 21.1 0.0 0.00096 19.4 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KEZ40977.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MMS1_N PF10433.9 KEZ40978.1 - 1.4e-55 188.9 0.0 1.7e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.18 KEZ40979.1 - 4.7e-14 52.6 0.0 1.3e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Vps52 PF04129.12 KEZ40980.1 - 3.4e-124 415.4 0.0 4.3e-124 415.1 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KEZ40980.1 - 0.00049 18.6 0.0 0.00094 17.7 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 Exo70 PF03081.15 KEZ40980.1 - 0.002 17.3 0.1 0.0039 16.3 0.1 1.5 1 0 0 1 1 1 1 Exo70 exocyst complex subunit eIF-5a PF01287.20 KEZ40981.1 - 2.5e-28 98.0 1.0 3.4e-28 97.5 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KEZ40981.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.24 KEZ40981.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain ubiquitin PF00240.23 KEZ40982.1 - 1.5e-33 114.3 0.6 2.4e-33 113.7 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KEZ40982.1 - 1.7e-31 107.8 11.1 2.8e-31 107.2 11.1 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KEZ40982.1 - 2.3e-15 56.1 0.7 3.7e-15 55.5 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KEZ40982.1 - 5.4e-05 23.6 0.2 0.00018 21.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KEZ40982.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KEZ40982.1 - 0.013 15.8 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KEZ40982.1 - 0.025 14.7 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KEZ40982.1 - 0.1 13.2 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KEZ40982.1 - 0.29 11.2 1.2 20 5.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Tash_PEST PF07708.11 KEZ40982.1 - 2.4 8.4 4.3 5.1 7.4 1.5 2.4 2 0 0 2 2 2 0 Tash protein PEST motif Yip1 PF04893.17 KEZ40983.1 - 2.8e-11 43.4 16.8 5e-11 42.6 16.8 1.5 1 1 0 1 1 1 1 Yip1 domain DUF347 PF03988.12 KEZ40983.1 - 5 7.4 9.0 2.9 8.2 4.1 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Rhodanese PF00581.20 KEZ40984.1 - 1e-12 48.5 0.0 1.7e-12 47.8 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 KEZ40985.1 - 3.5e-53 181.0 0.0 6.1e-53 180.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Mak10 PF04112.13 KEZ40985.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TGT PF01702.18 KEZ40986.1 - 1.1e-130 435.8 0.0 1.3e-130 435.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RecA_dep_nuc PF16786.5 KEZ40986.1 - 0.032 14.4 0.2 0.067 13.3 0.2 1.5 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease Mit_ribos_Mrp51 PF11709.8 KEZ40987.1 - 1.1e-96 324.7 0.0 1.4e-96 324.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.18 KEZ40988.1 - 2.2e-59 198.7 0.4 2.5e-59 198.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 SH3_2 PF07653.17 KEZ40989.1 - 6.9e-11 41.7 0.0 1.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ40989.1 - 1.1e-10 40.9 0.2 1.1e-10 40.9 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KEZ40989.1 - 1.7e-09 37.4 0.2 4e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 KEZ40989.1 - 0.0027 17.8 9.8 0.0027 17.8 9.8 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 KEZ40989.1 - 1.9 6.5 11.3 3.2 5.7 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi GCP_C_terminal PF04130.13 KEZ40990.1 - 4.9e-23 82.1 0.0 1.3e-22 80.7 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEZ40990.1 - 3e-22 79.6 0.3 4.7e-22 79.0 0.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Senescence PF06911.12 KEZ40991.1 - 6e-54 183.1 6.3 1e-53 182.4 6.3 1.4 1 0 0 1 1 1 1 Senescence-associated protein DUF3824 PF12868.7 KEZ40991.1 - 0.016 15.9 3.1 0.04 14.6 3.1 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_60s PF00428.19 KEZ40991.1 - 1.6 9.4 5.2 0.72 10.5 1.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.18 KEZ40992.1 - 1.6e-20 73.3 0.0 2.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ40992.1 - 5.4e-07 29.6 7.3 1e-06 28.7 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_33 PF10017.9 KEZ40993.1 - 4e-57 193.7 0.4 3.2e-42 144.8 0.1 2.2 1 1 1 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KEZ40993.1 - 5.1e-18 65.6 0.2 1.4e-16 60.9 0.2 2.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KEZ40993.1 - 7.5e-05 23.2 2.3 7.5e-05 23.2 0.3 2.1 2 0 0 2 2 2 1 DinB superfamily GyrI-like PF06445.15 KEZ40993.1 - 0.00035 20.9 0.0 0.00087 19.6 0.0 1.6 1 0 0 1 1 1 1 GyrI-like small molecule binding domain IF-2B PF01008.17 KEZ40994.1 - 1.4e-38 132.7 0.0 1.7e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Radical_SAM PF04055.21 KEZ40995.1 - 6.9e-09 36.3 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEZ40995.1 - 0.00017 21.9 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KEZ40995.1 - 0.051 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain RSN1_7TM PF02714.15 KEZ40996.1 - 6.4e-85 284.8 24.5 6.4e-85 284.8 24.5 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEZ40996.1 - 6.8e-44 149.4 0.4 6.8e-44 149.4 0.4 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEZ40996.1 - 3.5e-40 138.1 0.1 5e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KEZ40996.1 - 1.8e-29 101.7 0.1 1e-28 99.3 0.1 2.2 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter WSC PF01822.19 KEZ40997.1 - 2.9e-09 37.0 9.1 5.1e-09 36.2 9.1 1.4 1 0 0 1 1 1 1 WSC domain PTP_tm PF18861.1 KEZ40997.1 - 0.0045 17.0 1.3 0.0071 16.4 1.3 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4448 PF14610.6 KEZ40997.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4328 PF14219.6 KEZ40997.1 - 0.087 12.4 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Podoplanin PF05808.11 KEZ40997.1 - 0.15 12.1 0.8 0.31 11.1 0.8 1.4 1 0 0 1 1 1 0 Podoplanin PGF-CTERM PF18204.1 KEZ40997.1 - 0.17 11.9 3.5 0.28 11.2 3.5 1.4 1 0 0 1 1 1 0 PGF-CTERM motif Mid2 PF04478.12 KEZ40997.1 - 0.19 11.6 0.2 0.43 10.4 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF5305 PF17231.2 KEZ40997.1 - 0.2 11.1 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SKG6 PF08693.10 KEZ40997.1 - 2.2 7.7 6.4 4.7 6.7 6.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2613 PF11021.8 KEZ40997.1 - 5.1 7.3 7.6 0.14 12.3 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Solute_trans_a PF03619.16 KEZ40998.1 - 6.6e-85 284.8 26.3 7.8e-85 284.6 26.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1422 PF07226.11 KEZ40998.1 - 5.9 6.9 10.1 21 5.2 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) THOC2_N PF16134.5 KEZ40999.1 - 1e-245 817.3 0.0 1.8e-245 816.5 0.0 1.4 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KEZ40999.1 - 6e-98 327.8 0.4 1e-97 327.0 0.4 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KEZ40999.1 - 3.4e-29 100.7 0.2 8.5e-29 99.4 0.2 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.20 KEZ41000.1 - 3.3e-47 161.3 0.0 1.9e-46 158.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ41000.1 - 8.1e-05 23.3 2.1 0.00029 21.5 2.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family VASt PF16016.5 KEZ41001.1 - 9.3e-38 130.0 0.0 2e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KEZ41001.1 - 2.8e-25 88.4 0.0 5.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Spc24 PF08286.11 KEZ41002.1 - 0.0074 16.5 5.0 1 9.6 0.9 2.9 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DivIVA PF05103.13 KEZ41002.1 - 0.019 15.0 8.4 0.73 9.9 2.7 2.7 2 0 0 2 2 2 0 DivIVA protein bZIP_1 PF00170.21 KEZ41002.1 - 0.044 13.9 11.7 1.8 8.7 4.1 3.3 2 1 0 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.10 KEZ41002.1 - 0.057 13.6 0.4 0.16 12.2 0.4 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 KEZ41002.1 - 0.099 12.6 10.1 1.1 9.3 3.4 2.6 1 1 0 2 2 2 0 Prefoldin subunit Sec34 PF04136.15 KEZ41002.1 - 0.14 12.1 0.8 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Sec34-like family Phage_GP20 PF06810.11 KEZ41002.1 - 0.17 11.7 8.3 0.43 10.4 3.0 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 BLOC1_2 PF10046.9 KEZ41002.1 - 0.23 11.8 2.7 4.5 7.6 0.3 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ax_dynein_light PF10211.9 KEZ41002.1 - 0.31 10.9 8.3 2 8.3 1.7 2.5 2 0 0 2 2 2 0 Axonemal dynein light chain SIKE PF05769.11 KEZ41002.1 - 0.38 10.7 6.2 1.2 9.0 6.2 1.7 1 1 0 1 1 1 0 SIKE family GAS PF13851.6 KEZ41002.1 - 0.44 9.9 13.5 0.17 11.2 6.6 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 KEZ41002.1 - 0.7 10.2 9.3 1.1 9.6 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 KEZ41002.1 - 0.73 10.0 7.3 0.93 9.6 1.4 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 KEZ41002.1 - 0.98 9.5 10.5 0.84 9.7 2.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 KEZ41002.1 - 1 7.8 12.4 2.2 6.7 12.4 1.5 1 1 0 1 1 1 0 Macoilin family DUF812 PF05667.11 KEZ41002.1 - 1.2 8.0 8.1 0.04 12.8 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) BRE1 PF08647.11 KEZ41002.1 - 1.2 9.2 15.9 0.44 10.6 3.7 3.1 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 KEZ41002.1 - 1.4 9.6 0.0 1.4 9.6 0.0 3.9 4 0 0 4 4 3 0 SlyX SOGA PF11365.8 KEZ41002.1 - 2.8 9.1 12.6 2 9.6 2.0 3.6 2 1 1 3 3 3 0 Protein SOGA DUF4446 PF14584.6 KEZ41002.1 - 4 7.4 5.9 28 4.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TACC_C PF05010.14 KEZ41002.1 - 4.6 7.0 9.5 6.7 6.4 4.1 2.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spectrin PF00435.21 KEZ41002.1 - 5.7 7.5 8.7 1.9 9.0 4.1 2.4 2 0 0 2 2 2 0 Spectrin repeat KASH_CCD PF14662.6 KEZ41002.1 - 5.7 6.7 11.1 19 5.0 11.1 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 KEZ41002.1 - 9.1 6.5 10.5 7.1e+02 0.5 10.6 2.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 KxDL PF10241.9 KEZ41002.1 - 9.3 6.6 10.3 1.1 9.6 1.8 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Fungal_trans_2 PF11951.8 KEZ41003.1 - 8.1e-05 21.6 0.3 0.00023 20.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41003.1 - 0.00068 19.7 1.0 0.0014 18.7 1.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2418 PF10332.9 KEZ41004.1 - 8.8e-37 125.5 0.3 1.8e-36 124.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 KEZ41005.1 - 2.6e-27 95.0 0.3 3e-27 94.8 0.3 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2570 PF10828.8 KEZ41005.1 - 0.06 13.2 0.0 0.099 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) pPIWI_RE_REase PF18154.1 KEZ41005.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 REase associating with pPIWI_RE E1_DerP2_DerF2 PF02221.15 KEZ41006.1 - 8.9e-29 100.6 0.4 1e-28 100.4 0.4 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KEZ41006.1 - 0.0033 17.8 0.0 0.0065 16.8 0.0 1.5 1 1 0 1 1 1 1 ML-like domain Alph_Pro_TM PF09608.10 KEZ41006.1 - 0.093 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) MF_alpha_N PF05436.11 KEZ41006.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus RTP1_C2 PF10304.9 KEZ41006.1 - 0.28 10.9 1.5 0.41 10.4 0.1 2.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Adenylsucc_synt PF00709.21 KEZ41007.1 - 8e-168 558.7 0.0 9.1e-168 558.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1719 PF08224.11 KEZ41007.1 - 0.18 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Glycos_transf_4 PF00953.21 KEZ41008.1 - 2.8e-29 102.1 9.0 2.8e-29 102.1 9.0 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 4 F-box-like PF12937.7 KEZ41009.1 - 3.4e-05 23.6 0.0 6.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like Serglycin PF04360.12 KEZ41009.1 - 0.0011 18.9 1.2 0.0011 18.9 1.2 2.6 3 0 0 3 3 3 1 Serglycin F-box-like_2 PF13013.6 KEZ41009.1 - 0.0039 17.1 0.2 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.33 KEZ41009.1 - 0.004 17.0 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain FAM110_N PF14161.6 KEZ41009.1 - 0.0096 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 1 Centrosome-associated N terminus SGTA_dimer PF16546.5 KEZ41010.1 - 0.033 14.0 0.1 0.066 13.0 0.1 1.5 1 0 0 1 1 1 0 Homodimerisation domain of SGTA Cyclin_C PF02984.19 KEZ41010.1 - 0.062 13.4 0.1 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain Cyclin_N PF00134.23 KEZ41010.1 - 0.15 11.8 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain AA_permease PF00324.21 KEZ41011.1 - 1.3e-09 37.2 0.3 1.9e-09 36.7 0.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1819 PF08849.11 KEZ41011.1 - 0.26 11.1 0.1 0.44 10.3 0.1 1.2 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Aconitase PF00330.20 KEZ41012.1 - 8.4e-161 536.0 0.0 1.3e-160 535.5 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ41012.1 - 2.4e-41 141.1 0.0 4.7e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_16 PF10294.9 KEZ41013.1 - 1.7e-14 54.0 0.0 1.4e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 KEZ41013.1 - 0.0045 17.7 0.0 0.064 14.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41013.1 - 0.018 14.8 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41013.1 - 0.099 13.4 0.0 3.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain EF-hand_1 PF00036.32 KEZ41014.1 - 2.2e-25 86.3 12.2 3.2e-08 32.5 0.2 4.7 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 KEZ41014.1 - 5.1e-24 84.5 8.8 2.2e-15 56.8 1.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KEZ41014.1 - 8.3e-24 81.5 8.1 1.7e-06 27.5 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KEZ41014.1 - 2e-17 61.8 12.4 3.8e-05 23.0 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KEZ41014.1 - 5.8e-15 54.9 10.5 9.3e-06 25.4 0.7 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KEZ41014.1 - 7.5e-09 35.5 5.7 0.0039 17.1 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KEZ41014.1 - 0.0001 22.5 0.4 0.0051 17.1 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KEZ41014.1 - 0.00055 20.2 2.2 0.9 9.9 0.3 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 KEZ41014.1 - 0.024 13.5 0.3 1.8 7.4 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 KEZ41014.1 - 0.07 13.0 2.3 1.7 8.6 0.0 3.5 4 0 0 4 4 4 0 EF hand EF-hand_14 PF17959.1 KEZ41014.1 - 0.12 12.7 2.1 5.8 7.3 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain EF-hand_2 PF09068.11 KEZ41014.1 - 0.15 12.2 0.1 4.1 7.6 0.0 2.8 3 1 0 3 3 3 0 EF hand Fungal_trans PF04082.18 KEZ41015.1 - 1.2e-06 27.8 0.7 1.5e-06 27.5 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC45 PF02724.14 KEZ41016.1 - 3.9e-252 838.2 0.0 1.5e-251 836.2 0.0 2.5 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 KEZ41016.1 - 0.15 11.3 35.2 0.2 11.0 13.3 2.1 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 KEZ41016.1 - 0.38 10.5 28.6 0.014 15.1 8.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KEZ41016.1 - 0.39 8.9 28.3 1 7.5 9.3 2.2 2 0 0 2 2 2 0 Nop14-like family ISG65-75 PF11727.8 KEZ41016.1 - 1.4 8.1 8.7 3.1 6.9 8.7 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein FAM60A PF15396.6 KEZ41016.1 - 3.1 7.7 7.3 0.3 11.0 0.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Methyltransf_23 PF13489.6 KEZ41018.1 - 2.5e-14 53.5 0.0 3.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41018.1 - 1.2e-09 38.7 0.0 2.7e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41018.1 - 1.7e-07 31.1 0.0 2.2e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41018.1 - 6.2e-07 30.1 0.0 3.8e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41018.1 - 3.3e-06 27.7 0.0 5.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEZ41018.1 - 0.00024 20.6 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KEZ41018.1 - 0.0029 17.2 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEZ41018.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KEZ41018.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KEZ41018.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KEZ41018.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KEZ41018.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fungal_trans PF04082.18 KEZ41019.1 - 4.9e-17 61.8 0.0 8.9e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41019.1 - 2.1e-08 34.2 11.6 3.9e-08 33.3 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEZ41020.1 - 4.2e-22 78.6 44.1 1.3e-12 47.3 7.3 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ41020.1 - 1.9e-05 23.7 5.3 1.9e-05 23.7 5.3 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter COX7a PF02238.15 KEZ41020.1 - 0.67 10.4 7.7 2.6 8.5 0.1 3.9 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII NB-ARC PF00931.22 KEZ41021.1 - 3.2e-11 42.9 0.0 8.2e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 KEZ41021.1 - 1.8e-09 37.7 7.9 0.031 14.6 0.1 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ41021.1 - 2.6e-07 30.2 12.6 0.068 13.3 0.2 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat DUF676 PF05057.14 KEZ41021.1 - 5.7e-07 29.3 0.0 9.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_14 PF13428.6 KEZ41021.1 - 2e-06 28.1 9.9 0.35 11.8 0.2 5.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ41021.1 - 0.00023 21.5 12.4 0.38 11.5 0.7 5.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ41021.1 - 0.0003 20.7 1.0 9.6 6.7 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NACHT PF05729.12 KEZ41021.1 - 0.00035 20.5 0.0 0.0009 19.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 KEZ41021.1 - 0.00081 19.2 10.0 0.64 10.0 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ41021.1 - 0.001 19.6 8.1 1.5 9.4 0.3 4.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ41021.1 - 0.0019 18.1 9.1 0.16 12.1 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ41021.1 - 0.0019 17.9 5.0 1.7 8.6 0.1 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ41021.1 - 0.0049 17.5 12.9 0.28 11.9 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KEZ41021.1 - 0.01 16.5 0.1 0.069 13.7 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family PhoH PF02562.16 KEZ41021.1 - 0.014 14.9 0.1 0.036 13.5 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein TPR_6 PF13174.6 KEZ41021.1 - 0.017 15.7 6.7 1.7 9.4 0.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.6 KEZ41021.1 - 0.022 15.1 0.0 0.069 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 KEZ41021.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_11 PF13414.6 KEZ41021.1 - 0.21 11.3 1.3 1.3 8.7 0.0 3.0 3 0 0 3 3 3 0 TPR repeat LCAT PF02450.15 KEZ41021.1 - 0.22 10.7 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase WD40 PF00400.32 KEZ41023.1 - 7.6e-29 99.4 12.6 1.2e-06 29.1 0.6 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41023.1 - 5.8e-07 29.7 0.1 0.14 12.4 0.0 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ41023.1 - 0.00016 20.5 8.1 0.33 9.6 0.2 4.8 4 1 1 5 5 5 3 Nucleoporin Nup120/160 DUF5046 PF16465.5 KEZ41023.1 - 0.0081 15.6 0.4 0.11 11.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5046) BBS2_Mid PF14783.6 KEZ41023.1 - 0.032 14.3 0.0 0.62 10.1 0.0 3.0 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF5082 PF16888.5 KEZ41023.1 - 0.059 13.6 0.5 0.4 11.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4201 PF13870.6 KEZ41023.1 - 0.087 12.5 2.3 0.17 11.6 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 KEZ41023.1 - 0.33 11.5 3.9 0.84 10.2 3.8 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Sugarporin_N PF11471.8 KEZ41023.1 - 2.8 8.0 5.8 5.7 7.0 3.7 2.2 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension BCIP PF13862.6 KEZ41024.1 - 4.5e-62 209.5 0.0 5.5e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein FKBP_C PF00254.28 KEZ41025.1 - 2.8e-27 94.9 0.0 3.3e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.21 KEZ41026.1 - 1.8e-106 354.9 0.0 3.6e-71 239.4 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KEZ41026.1 - 8.6e-88 294.5 0.1 1.3e-87 293.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KEZ41026.1 - 1e-31 109.4 0.6 2.1e-31 108.5 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KEZ41026.1 - 3.5e-29 100.8 0.0 9e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KEZ41026.1 - 4.4e-26 90.9 1.7 1.2e-25 89.5 0.8 2.2 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle WD40 PF00400.32 KEZ41027.1 - 6.4e-09 36.3 2.5 0.00032 21.5 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KEZ41027.1 - 0.00041 19.4 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KEZ41027.1 - 0.0034 17.7 0.1 1.5 9.2 0.0 3.4 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Vps5 PF09325.10 KEZ41028.1 - 1.4e-12 47.7 2.4 2.3e-12 47.0 2.4 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KEZ41028.1 - 2.2e-08 34.1 0.0 4.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 KEZ41028.1 - 0.16 12.3 0.7 0.86 9.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat NST1 PF13945.6 KEZ41028.1 - 0.17 12.0 1.0 0.32 11.1 1.0 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator ADH_N PF08240.12 KEZ41029.1 - 3.8e-26 91.1 0.7 9.6e-26 89.8 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ41029.1 - 2.6e-13 50.1 2.1 2.1e-12 47.1 2.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ41029.1 - 8.8e-09 35.2 0.1 9.7e-05 21.9 0.1 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KEZ41029.1 - 0.0031 17.1 0.3 0.025 14.2 0.2 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KEZ41029.1 - 0.0042 16.4 0.2 0.008 15.5 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KEZ41029.1 - 0.018 14.7 0.3 0.035 13.7 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ41029.1 - 0.033 13.4 0.0 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ41029.1 - 0.051 13.8 1.5 0.39 11.0 0.7 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KEZ41029.1 - 0.056 12.8 0.1 0.099 12.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family AdoHcyase_NAD PF00670.21 KEZ41029.1 - 0.088 12.9 1.3 0.19 11.8 0.4 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PALP PF00291.25 KEZ41029.1 - 0.094 12.1 1.1 0.15 11.4 1.1 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ADH_zinc_N_2 PF13602.6 KEZ41029.1 - 0.12 13.5 0.0 0.26 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 KEZ41029.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 KEZ41029.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KEZ41029.1 - 0.15 11.9 0.2 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KEZ41029.1 - 0.25 10.0 0.5 0.38 9.4 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein MitMem_reg PF13012.6 KEZ41030.1 - 1e-11 45.2 0.1 2.9e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KEZ41030.1 - 4.1e-10 39.7 0.1 1.8e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Aldo_ket_red PF00248.21 KEZ41031.1 - 2.9e-74 249.9 0.0 3.3e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HNH_2 PF13391.6 KEZ41032.1 - 1.7e-15 56.9 0.0 7e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease tRNA-synt_1d PF00750.19 KEZ41033.1 - 9.8e-88 294.4 0.1 1.5e-87 293.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KEZ41033.1 - 1.4e-24 86.6 1.5 4.7e-24 84.8 0.3 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain GAPES2 PF17156.4 KEZ41033.1 - 0.05 13.4 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain DUF3323 PF11796.8 KEZ41033.1 - 0.077 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF3632 PF12311.8 KEZ41034.1 - 1.1e-30 107.3 3.2 1.7e-30 106.8 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MAS20 PF02064.15 KEZ41036.1 - 4.4e-42 143.2 0.6 5.2e-42 143.0 0.6 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Exo84_C PF16528.5 KEZ41037.1 - 3.7e-77 258.8 1.4 1.1e-76 257.3 1.4 1.8 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Metallophos PF00149.28 KEZ41037.1 - 3.3e-37 129.0 0.4 6.6e-37 128.0 0.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.11 KEZ41037.1 - 2e-13 50.2 0.7 2e-13 50.2 0.7 2.3 3 0 0 3 3 3 1 Vps51/Vps67 STPPase_N PF16891.5 KEZ41037.1 - 0.14 12.6 0.1 0.35 11.4 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Chitin_synth_2 PF03142.15 KEZ41038.1 - 5.2e-250 830.5 3.7 7.2e-250 830.1 3.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KEZ41038.1 - 1.1e-72 245.3 0.0 4.3e-72 243.4 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KEZ41038.1 - 1.8e-19 69.4 0.1 9.5e-19 67.1 0.2 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KEZ41038.1 - 2.4e-13 50.0 0.0 5.8e-10 39.2 0.0 3.1 3 0 0 3 3 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KEZ41038.1 - 8.4e-13 48.7 4.6 8.4e-13 48.7 4.6 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEZ41038.1 - 4.1e-10 39.9 0.2 5.8e-09 36.2 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ41038.1 - 0.00013 21.9 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 KEZ41038.1 - 0.004 17.1 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KEZ41038.1 - 0.011 16.1 0.2 0.066 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KEZ41038.1 - 0.023 15.2 0.0 0.055 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KEZ41038.1 - 0.029 14.1 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KEZ41038.1 - 0.03 13.9 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ41038.1 - 0.036 14.2 0.1 1.2 9.3 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 KEZ41038.1 - 0.057 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEZ41038.1 - 0.12 12.8 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KEZ41038.1 - 0.16 12.3 0.4 0.59 10.4 0.1 2.2 2 0 0 2 2 1 0 AAA domain Glyco_transf_21 PF13506.6 KEZ41038.1 - 0.17 11.3 0.3 0.69 9.4 0.3 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 CLP1_P PF16575.5 KEZ41038.1 - 0.24 11.2 0.7 46 3.7 0.4 3.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Chitin_synth_2 PF03142.15 KEZ41039.1 - 4.7e-228 758.1 0.1 6.9e-228 757.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 KEZ41039.1 - 5.4e-16 58.5 3.4 4.3e-12 46.0 0.0 3.3 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 KEZ41039.1 - 8.6e-16 57.6 1.7 5.7e-15 55.0 2.3 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KEZ41039.1 - 2.6e-13 50.4 2.4 2.6e-13 50.4 2.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEZ41039.1 - 3.7e-11 43.4 0.0 1.6e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KEZ41039.1 - 2.6e-08 32.6 0.0 1.1e-07 30.5 0.0 1.7 1 1 1 2 2 2 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 KEZ41039.1 - 0.00036 20.4 0.0 0.086 12.6 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ41039.1 - 0.0011 18.5 0.0 0.0035 16.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 21 BCDHK_Adom3 PF10436.9 KEZ41040.1 - 6.3e-44 149.7 0.0 8.4e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEZ41040.1 - 8.4e-11 42.4 0.0 3.7e-09 37.1 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEZ41040.1 - 0.069 13.0 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 KEZ41041.1 - 3.1e-11 43.8 0.0 7.1e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 RIBIOP_C PF04950.12 KEZ41042.1 - 2.3e-95 319.4 0.2 2.3e-95 319.4 0.2 1.6 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KEZ41042.1 - 5.4e-28 96.9 0.0 2.4e-27 94.9 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_18 PF13238.6 KEZ41042.1 - 3.1e-05 24.5 1.2 0.034 14.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KEZ41042.1 - 9e-05 22.8 0.0 0.00026 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ41042.1 - 0.00012 22.5 0.0 0.00034 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEZ41042.1 - 0.00028 20.9 0.0 0.00066 19.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KEZ41042.1 - 0.00032 21.2 0.0 0.0012 19.4 0.0 2.0 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 KEZ41042.1 - 0.00051 20.1 0.0 0.0024 18.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEZ41042.1 - 0.00095 18.8 0.0 0.26 10.8 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.14 KEZ41042.1 - 0.0011 18.8 0.3 0.44 10.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KEZ41042.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ41042.1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 KEZ41042.1 - 0.0051 17.2 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEZ41042.1 - 0.0094 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KEZ41042.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 KEZ41042.1 - 0.012 15.3 0.0 0.046 13.5 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KEZ41042.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 KEZ41042.1 - 0.015 15.6 0.0 0.056 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ41042.1 - 0.015 15.2 0.0 0.11 12.4 0.0 2.3 3 0 0 3 3 2 0 RsgA GTPase AAA_14 PF13173.6 KEZ41042.1 - 0.019 15.0 0.0 0.069 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEZ41042.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KEZ41042.1 - 0.036 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 NTPase Ploopntkinase3 PF18751.1 KEZ41042.1 - 0.044 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ATPase_2 PF01637.18 KEZ41042.1 - 0.058 13.3 0.3 0.2 11.5 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KEZ41042.1 - 0.061 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KEZ41042.1 - 0.061 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KEZ41042.1 - 0.093 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ41042.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KEZ41042.1 - 0.11 12.4 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 KEZ41042.1 - 0.44 10.3 0.0 0.44 10.3 0.0 3.1 4 0 0 4 4 2 0 AAA domain AAA_23 PF13476.6 KEZ41042.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.8 3 1 0 4 4 3 0 AAA domain GST_N_2 PF13409.6 KEZ41043.1 - 4.4e-25 87.8 0.2 2.3e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ41043.1 - 1.8e-13 50.3 0.0 5.3e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEZ41043.1 - 9.1e-06 26.0 0.0 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ41043.1 - 0.00048 20.3 0.0 0.0013 18.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEZ41043.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KEZ41043.1 - 0.0039 17.7 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPR_12 PF13424.6 KEZ41044.1 - 2e-62 207.4 18.3 2.5e-18 66.1 0.7 6.5 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ41044.1 - 7.7e-59 194.1 8.7 5.6e-11 41.9 0.0 7.9 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ41044.1 - 2.4e-16 58.8 10.0 0.0047 16.7 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ41044.1 - 1e-15 56.6 7.9 0.0011 19.1 0.1 7.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ41044.1 - 1.2e-11 43.7 8.1 0.017 15.2 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ41044.1 - 1.6e-10 40.5 0.1 0.049 14.3 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ41044.1 - 4.2e-09 35.8 4.0 0.0082 16.1 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ41044.1 - 7.8e-09 35.1 0.0 1.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 KEZ41044.1 - 1.1e-08 34.9 0.8 6.2e-05 22.5 0.8 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KEZ41044.1 - 1.6e-08 35.0 2.1 0.037 14.7 0.0 4.7 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ41044.1 - 1.8e-05 25.1 1.4 4.3 8.4 0.0 6.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ41044.1 - 2.8e-05 24.5 0.7 0.48 11.0 0.5 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KEZ41044.1 - 3.9e-05 23.0 0.0 0.00014 21.2 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_17 PF13431.6 KEZ41044.1 - 0.0009 19.5 0.2 0.6 10.6 0.0 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ41044.1 - 0.0013 19.2 0.1 0.0037 17.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ41044.1 - 0.028 14.7 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SHNi-TPR PF10516.9 KEZ41044.1 - 0.56 9.7 2.4 15 5.1 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 KEZ41044.1 - 0.68 10.7 4.2 10 7.0 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat Nucleo_P87 PF07267.11 KEZ41045.1 - 1.4 7.7 13.8 1.6 7.5 13.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3292 PF11696.8 KEZ41045.1 - 7.5 4.8 9.8 13 4.0 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RhoGAP PF00620.27 KEZ41046.1 - 1.6e-46 157.9 2.2 3e-46 157.0 0.0 2.5 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 KEZ41046.1 - 3.8e-14 52.7 16.9 2.7e-09 37.1 1.6 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.12 KEZ41046.1 - 0.22 11.2 7.0 5.6 6.7 0.6 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain Zn-ribbon_8 PF09723.10 KEZ41046.1 - 4.9 7.4 18.9 1.1 9.5 1.2 4.2 3 1 1 4 4 4 0 Zinc ribbon domain CLASP_N PF12348.8 KEZ41047.1 - 7.7e-129 428.0 1.8 3.9e-84 281.8 0.0 2.7 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 KEZ41047.1 - 0.012 15.8 0.3 0.25 11.5 0.0 3.3 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KEZ41047.1 - 0.023 13.3 2.3 3.5 6.1 0.0 3.8 4 0 0 4 4 4 0 Adaptin N terminal region Cnd1 PF12717.7 KEZ41047.1 - 0.034 14.2 2.1 3 7.8 0.0 3.9 3 3 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ECH_2 PF16113.5 KEZ41047.1 - 0.043 13.3 0.4 0.1 12.0 0.4 1.6 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase HEAT PF02985.22 KEZ41047.1 - 0.046 14.0 0.1 16 6.1 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.7 KEZ41047.1 - 0.082 13.5 0.0 34 5.1 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Iso_dh PF00180.20 KEZ41048.1 - 3.1e-100 335.7 0.0 3.8e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KEZ41048.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Pkinase PF00069.25 KEZ41049.1 - 2.3e-22 79.6 0.0 3.4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KEZ41049.1 - 1.9e-08 34.8 12.4 1.5e-05 25.6 0.3 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.22 KEZ41049.1 - 9.5e-07 28.6 3.0 2 8.9 0.1 6.9 6 0 0 6 6 6 1 HEAT repeat Pkinase_Tyr PF07714.17 KEZ41049.1 - 0.00032 20.1 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KEZ41049.1 - 0.00074 19.9 2.5 6.4 7.2 0.2 4.4 3 1 0 4 4 4 2 HEAT repeats Kinase-like PF14531.6 KEZ41049.1 - 0.037 13.3 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.7 KEZ41049.1 - 0.048 13.7 0.2 1.2 9.1 0.1 3.0 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 KEZ41049.1 - 0.22 10.4 0.5 0.84 8.5 0.1 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SH3_9 PF14604.6 KEZ41050.1 - 1.3e-05 24.9 0.1 2.7e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ41050.1 - 0.00022 20.8 0.1 0.00047 19.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF4690 PF15756.5 KEZ41050.1 - 0.0013 19.3 0.3 0.0013 19.3 0.3 2.4 3 0 0 3 3 3 1 Small Novel Rich in Cartilage Mucin15 PF15672.5 KEZ41050.1 - 0.0038 16.8 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 DAP10 PF07213.11 KEZ41050.1 - 0.085 12.8 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 KEZ41050.1 - 0.15 13.0 0.0 0.33 11.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_Omp PF13488.6 KEZ41050.1 - 2.7 8.1 14.8 24 5.0 0.0 2.4 2 0 0 2 2 2 0 Glycine zipper SRP68 PF16969.5 KEZ41052.1 - 4.1e-188 626.9 3.7 4.8e-188 626.7 3.7 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Mis14 PF08641.12 KEZ41052.1 - 0.023 15.0 0.1 0.023 15.0 0.1 3.3 3 1 0 3 3 3 0 Kinetochore protein Mis14 like Surfac_D-trimer PF09006.11 KEZ41052.1 - 0.14 12.1 0.2 20 5.2 0.0 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Propep_M14 PF02244.16 KEZ41052.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase activation peptide eIF3_N PF09440.10 KEZ41052.1 - 1.1 9.6 3.9 14 6.1 0.8 3.2 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain HSP70 PF00012.20 KEZ41053.1 - 9.2e-266 882.8 14.1 1.1e-265 882.6 14.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ41053.1 - 5.7e-15 54.9 1.1 4.3e-12 45.5 0.2 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KEZ41053.1 - 0.00094 18.9 0.1 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DIOX_N PF14226.6 KEZ41053.1 - 0.1 13.4 0.1 0.28 11.9 0.1 1.7 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Tom22 PF04281.13 KEZ41053.1 - 0.95 9.2 5.8 1.4 8.7 5.2 1.7 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GlutR_dimer PF00745.20 KEZ41053.1 - 1.5 9.3 5.5 6.6 7.3 0.0 3.7 3 1 1 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF2415 PF10313.9 KEZ41054.1 - 2.2e-12 46.7 0.0 1.4e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KEZ41054.1 - 0.00011 22.4 0.0 0.43 10.9 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEZ41054.1 - 0.0014 19.4 0.1 3 8.9 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat eIF3g PF12353.8 KEZ41055.1 - 2.1e-43 147.7 4.5 3.8e-43 146.9 4.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KEZ41055.1 - 8.5e-16 57.5 0.1 1.8e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 KEZ41055.1 - 0.019 15.3 0.2 0.037 14.4 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 KEZ41055.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif NosL PF05573.12 KEZ41055.1 - 0.62 10.4 3.2 2.6 8.4 0.1 2.4 2 0 0 2 2 2 0 NosL PEMT PF04191.13 KEZ41056.1 - 2.3e-55 185.5 16.2 3.3e-35 120.7 1.1 2.7 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 KEZ41056.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 UPF0093 PF03653.13 KEZ41056.1 - 0.057 13.6 1.4 0.2 11.9 1.4 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) SKICH PF17751.1 KEZ41056.1 - 0.071 13.7 0.1 1.3 9.6 0.1 2.3 1 1 0 1 1 1 0 SKICH domain Lactonase PF10282.9 KEZ41057.1 - 1.8e-80 270.8 0.0 1.2e-79 268.0 0.0 1.8 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.18 KEZ41058.1 - 4.8e-09 36.2 7.9 4.8e-09 36.2 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.21 KEZ41060.1 - 7.2e-06 26.1 13.8 1.3e-05 25.3 13.8 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain SDA1 PF05285.12 KEZ41060.1 - 0.0014 18.2 15.7 0.0014 18.2 15.7 2.1 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.12 KEZ41060.1 - 3.4 5.7 29.7 0.016 13.5 17.1 2.0 2 0 0 2 2 2 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 KEZ41060.1 - 9.6 6.4 35.1 0.74 10.0 17.8 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3433 PF11915.8 KEZ41061.1 - 2.4e-26 92.0 23.5 2.5e-17 63.1 1.6 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 KEZ41061.1 - 0.085 13.0 2.8 11 6.2 0.1 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Aph-1 PF06105.12 KEZ41061.1 - 0.4 10.0 4.7 0.19 11.1 0.3 2.3 1 1 0 2 2 2 0 Aph-1 protein Cpn10 PF00166.21 KEZ41062.1 - 2.5e-28 98.0 0.0 2.8e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit HU-CCDC81_bac_1 PF18174.1 KEZ41062.1 - 0.21 11.5 0.2 18 5.3 0.1 2.4 2 1 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 Pkinase PF00069.25 KEZ41063.1 - 6.8e-49 166.6 0.0 3.7e-48 164.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41063.1 - 6e-22 78.2 0.1 2.2e-21 76.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KEZ41063.1 - 0.0019 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KEZ41063.1 - 0.029 14.0 0.0 7.1 6.2 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KEZ41063.1 - 0.037 13.6 0.0 0.091 12.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KEZ41063.1 - 0.21 10.5 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L11 PF00298.19 KEZ41064.1 - 3.3e-29 101.2 0.1 5.6e-29 100.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KEZ41064.1 - 2.5e-26 91.3 0.1 4.1e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain FTA2 PF13095.6 KEZ41065.1 - 1.8e-73 246.7 0.0 7.6e-73 244.7 0.0 1.7 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Sulf_transp PF04143.14 KEZ41066.1 - 1.7e-28 100.1 17.8 2.9e-28 99.3 17.6 1.5 1 1 0 1 1 1 1 Sulphur transport Ribonuc_L-PSP PF01042.21 KEZ41067.1 - 2e-21 76.2 0.0 2.3e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SNF2_N PF00176.23 KEZ41068.1 - 5.4e-48 163.5 0.0 2.2e-41 141.8 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ41068.1 - 5.6e-16 58.9 0.0 1.2e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KEZ41068.1 - 9.1e-06 25.5 8.1 9.1e-06 25.5 8.1 1.6 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KEZ41068.1 - 0.00015 21.6 7.0 0.00015 21.6 7.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KEZ41068.1 - 0.00031 20.7 4.4 0.00065 19.7 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEZ41068.1 - 0.00045 20.0 9.2 0.00092 19.0 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEZ41068.1 - 0.00072 19.8 7.5 0.00072 19.8 7.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEZ41068.1 - 0.0012 18.6 6.7 0.0012 18.6 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KEZ41068.1 - 0.0023 18.1 6.5 0.0023 18.1 6.5 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 ERCC3_RAD25_C PF16203.5 KEZ41068.1 - 0.0023 17.2 0.1 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEZ41068.1 - 0.0098 15.9 0.0 0.029 14.4 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit zf-rbx1 PF12678.7 KEZ41068.1 - 0.014 15.7 4.1 0.03 14.6 4.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KEZ41068.1 - 0.015 15.2 8.3 0.015 15.2 8.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HAD_SAK_2 PF18143.1 KEZ41068.1 - 0.022 15.1 0.1 0.052 13.9 0.1 1.7 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Rtf2 PF04641.12 KEZ41068.1 - 0.034 13.5 2.4 0.069 12.5 2.4 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger PSRP-3_Ycf65 PF04839.13 KEZ41068.1 - 0.039 14.2 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) zinc-ribbons_6 PF07191.12 KEZ41068.1 - 0.084 12.9 5.6 0.19 11.7 5.6 1.6 1 0 0 1 1 1 0 zinc-ribbons HDA2-3 PF11496.8 KEZ41068.1 - 0.098 11.8 0.1 0.29 10.3 0.1 1.8 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 zf-ANAPC11 PF12861.7 KEZ41068.1 - 0.13 12.3 1.3 0.3 11.2 1.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KEZ41068.1 - 0.61 9.9 8.5 0.35 10.7 5.3 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KEZ41068.1 - 0.81 9.9 7.8 1.6 9.0 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CDO_I PF05995.12 KEZ41069.1 - 8.2e-39 132.6 0.0 1.1e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KEZ41069.1 - 0.0054 16.2 0.2 0.01 15.3 0.2 1.5 1 1 0 1 1 1 1 PCO_ADO PI3_PI4_kinase PF00454.27 KEZ41070.1 - 4.3e-37 128.3 0.0 7.8e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.23 KEZ41072.1 - 2.9e-68 230.1 0.0 4.3e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ41072.1 - 1e-09 38.7 0.0 4.9e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ41072.1 - 6.1e-07 29.4 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEZ41072.1 - 0.00081 19.4 0.0 0.0077 16.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KEZ41072.1 - 0.00097 19.1 3.4 0.002 18.1 3.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain FpoO PF10621.9 KEZ41072.1 - 0.054 13.8 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO zf-C3HC4 PF00097.25 KEZ41072.1 - 0.46 10.4 3.8 1 9.3 3.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ41072.1 - 0.69 9.8 7.4 2.3 8.2 7.0 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEZ41072.1 - 0.73 10.2 3.7 1.7 9.0 3.7 1.7 1 0 0 1 1 1 0 Ring finger domain GCP_N_terminal PF17681.1 KEZ41073.1 - 2.6e-64 217.8 0.0 5e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KEZ41073.1 - 2e-62 211.4 0.7 2e-62 211.4 0.7 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 KEZ41074.1 - 3.9e-56 189.5 0.1 5.1e-56 189.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEZ41074.1 - 1.8e-12 46.7 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 KEZ41075.1 - 2.5e-16 59.5 0.6 8.2e-15 54.5 0.6 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41075.1 - 5.4e-08 32.8 11.9 9.7e-08 32.0 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ41075.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4461 PF14688.6 KEZ41075.1 - 0.023 14.5 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) Ldl_recept_a PF00057.18 KEZ41075.1 - 0.57 10.5 5.9 1 9.6 5.9 1.4 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Asp_protease PF09668.10 KEZ41076.1 - 3.7e-59 198.0 0.3 5.4e-59 197.4 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KEZ41076.1 - 1.7e-24 86.2 0.1 3.5e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KEZ41076.1 - 4.5e-12 46.4 0.1 8.8e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KEZ41076.1 - 6.3e-10 38.7 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KEZ41076.1 - 1.8e-07 30.9 0.3 4.9e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain RVP PF00077.20 KEZ41076.1 - 8.8e-05 22.8 0.0 0.00028 21.2 0.0 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KEZ41076.1 - 0.00017 21.3 0.0 0.00034 20.4 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KEZ41076.1 - 0.0008 19.2 0.1 0.0019 18.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KEZ41076.1 - 0.038 14.5 0.1 0.11 13.0 0.1 1.9 2 1 0 2 2 2 0 Ubiquitin-like domain XPC-binding PF09280.11 KEZ41076.1 - 0.18 11.6 4.3 0.38 10.5 1.5 2.5 2 0 0 2 2 2 0 XPC-binding domain Acetyltransf_10 PF13673.7 KEZ41077.1 - 3.1e-08 33.6 0.0 5.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ41077.1 - 3.1e-08 33.9 0.0 5.9e-08 33.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ41077.1 - 3.1e-07 30.7 0.0 5.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ41077.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein NOG1_N PF17835.1 KEZ41078.1 - 1.5e-50 171.3 0.2 1.5e-50 171.3 0.2 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KEZ41078.1 - 2.9e-29 100.8 2.6 6.2e-29 99.7 2.6 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KEZ41078.1 - 5.1e-25 87.0 0.2 1.4e-24 85.6 0.2 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KEZ41078.1 - 1.7e-13 50.7 0.0 3.8e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ41078.1 - 3.1e-05 23.5 0.0 7.7e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEZ41078.1 - 0.037 14.1 1.0 2.4 8.2 0.0 2.9 2 1 1 3 3 3 0 Dynamin family AAA_18 PF13238.6 KEZ41078.1 - 0.046 14.3 0.2 18 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain PPV_E1_C PF00519.17 KEZ41078.1 - 0.051 12.4 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase EF-1_beta_acid PF10587.9 KEZ41078.1 - 0.11 12.9 0.3 0.11 12.9 0.3 4.0 5 1 0 5 5 5 0 Eukaryotic elongation factor 1 beta central acidic region AAA_16 PF13191.6 KEZ41078.1 - 0.2 12.0 2.1 2 8.8 0.0 3.1 2 1 0 3 3 3 0 AAA ATPase domain GDI PF00996.18 KEZ41079.1 - 1.4e-191 636.7 0.0 1.6e-191 636.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KEZ41079.1 - 0.11 12.7 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 KEZ41080.1 - 5.2e-23 81.0 0.2 5.2e-23 81.0 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.18 KEZ41081.1 - 3.3e-12 46.0 0.1 5.4e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KEZ41081.1 - 3.7e-07 30.3 7.7 3.6e-06 27.1 1.3 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ41081.1 - 0.00036 21.1 15.0 0.064 14.1 5.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 KEZ41081.1 - 0.0023 18.2 4.0 0.0045 17.2 4.0 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KEZ41081.1 - 0.037 14.5 14.8 0.37 11.3 7.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KEZ41081.1 - 0.07 13.4 3.7 8.8 6.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Peptidase_S64 PF08192.11 KEZ41083.1 - 0.0002 20.0 0.0 0.00029 19.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.6 KEZ41083.1 - 0.033 15.1 0.0 0.9 10.4 0.0 2.4 2 0 0 2 2 2 0 Trypsin-like peptidase domain Ysc84 PF04366.12 KEZ41084.1 - 5.9e-31 106.9 0.0 9.7e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator NOA36 PF06524.12 KEZ41084.1 - 2.5 7.3 10.8 4.9 6.4 10.8 1.4 1 0 0 1 1 1 0 NOA36 protein Actin PF00022.19 KEZ41085.1 - 2.4e-16 59.4 0.1 6.4e-12 44.8 0.0 3.1 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.13 KEZ41085.1 - 0.0012 17.7 0.0 0.77 8.5 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KEZ41085.1 - 0.029 14.8 0.0 0.062 13.7 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsA DUF4045 PF13254.6 KEZ41085.1 - 0.055 13.1 4.5 0.099 12.3 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FA_desaturase PF00487.24 KEZ41086.1 - 1.4e-16 61.1 10.5 1.4e-16 61.1 10.5 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEZ41086.1 - 3.8e-14 52.6 0.1 1e-13 51.2 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 KEZ41087.1 - 2.4e-10 40.2 0.0 2.1e-09 37.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41087.1 - 8.3e-09 35.1 0.0 1.1e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.13 KEZ41088.1 - 1.2e-62 211.2 0.0 2e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KEZ41088.1 - 6.3e-33 114.4 0.4 1.2e-32 113.4 0.0 1.7 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KEZ41088.1 - 7.9e-21 74.9 0.0 2.1e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KEZ41088.1 - 1.2e-07 31.6 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KEZ41088.1 - 5e-07 29.8 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEZ41088.1 - 2.6e-06 27.6 0.0 7.9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEZ41088.1 - 4.7e-05 23.7 0.0 0.00058 20.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KEZ41088.1 - 5.3e-05 22.3 0.0 9.8e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KEZ41088.1 - 0.00022 21.0 0.0 0.00075 19.3 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KEZ41088.1 - 0.0006 20.4 0.2 0.075 13.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KEZ41088.1 - 0.00078 19.9 1.9 0.003 18.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KEZ41088.1 - 0.01 15.6 0.0 0.041 13.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KEZ41088.1 - 0.017 14.8 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ41088.1 - 0.035 13.6 0.2 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region F-box-like_2 PF13013.6 KEZ41088.1 - 0.039 13.9 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 1 0 F-box-like domain RNA_helicase PF00910.22 KEZ41088.1 - 0.043 14.2 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 KEZ41088.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ41088.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DUF445 PF04286.12 KEZ41088.1 - 0.059 13.2 4.6 0.13 12.1 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF445) NTPase_1 PF03266.15 KEZ41088.1 - 0.081 12.8 0.2 1.7 8.5 0.0 2.8 2 1 1 3 3 3 0 NTPase DDHD PF02862.17 KEZ41088.1 - 0.13 12.4 3.3 1.9 8.6 0.3 2.5 2 0 0 2 2 2 0 DDHD domain TERB2 PF15101.6 KEZ41088.1 - 1.9 8.5 8.3 1.4 9.0 1.6 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ABC_tran PF00005.27 KEZ41088.1 - 1.9 9.0 4.4 1 9.9 0.1 2.7 3 0 0 3 3 2 0 ABC transporter Med21 PF11221.8 KEZ41089.1 - 4.1e-43 147.1 8.9 4.6e-43 146.9 8.9 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.10 KEZ41089.1 - 0.00038 20.6 2.0 0.00047 20.3 2.0 1.2 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) DUF4455 PF14643.6 KEZ41089.1 - 0.0011 17.8 1.5 0.0011 17.8 1.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) Med9 PF07544.13 KEZ41089.1 - 0.0088 16.1 1.0 0.0088 16.1 1.0 2.3 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.8 KEZ41089.1 - 0.018 15.0 6.3 0.018 15.0 6.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HTH_5 PF01022.20 KEZ41089.1 - 0.068 13.1 0.6 5.3 7.0 0.3 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HAD_2 PF13419.6 KEZ41090.1 - 3.7e-08 33.7 0.0 6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ41090.1 - 1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRV_FeS PF05484.11 KEZ41090.1 - 0.057 13.4 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 LRV protein FeS4 cluster Pep3_Vps18 PF05131.14 KEZ41090.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family KH_1 PF00013.29 KEZ41091.1 - 3e-30 103.8 3.0 2.2e-06 27.4 0.4 7.2 7 0 0 7 7 7 5 KH domain OEP PF02321.18 KEZ41091.1 - 0.2 11.5 0.1 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein Eaf7 PF07904.13 KEZ41092.1 - 2.9e-21 75.9 8.4 2.9e-21 75.9 8.4 2.9 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 DUF2052 PF09747.9 KEZ41092.1 - 0.0037 17.4 19.4 0.025 14.7 7.5 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) DUF4554 PF15091.6 KEZ41092.1 - 0.39 9.6 4.4 0.37 9.6 3.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4554) DUF4746 PF15928.5 KEZ41092.1 - 0.42 10.0 18.4 0.27 10.6 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) GCP_C_terminal PF04130.13 KEZ41093.1 - 3.3e-75 253.4 0.0 7.8e-75 252.2 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KEZ41093.1 - 4.4e-29 102.1 0.0 6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Hist_deacetyl PF00850.19 KEZ41094.1 - 3.3e-53 181.2 0.1 4.7e-53 180.6 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PHP PF02811.19 KEZ41095.1 - 3.6e-10 40.4 0.0 6.3e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 PHP domain MOSC PF03473.17 KEZ41096.1 - 1.2e-29 102.9 0.0 1.8e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KEZ41096.1 - 1.9e-13 50.3 0.0 4.1e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Imm5 PF14423.6 KEZ41096.1 - 0.089 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 His_Phos_2 PF00328.22 KEZ41097.1 - 2.5e-109 366.2 0.0 1.3e-108 363.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KEZ41097.1 - 4.7e-36 122.8 0.0 1.2e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KEZ41097.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 KEZ41098.1 - 8.1e-84 280.8 0.0 1.1e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KEZ41098.1 - 3.2e-20 72.1 22.0 3.6e-08 33.9 0.1 8.8 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41098.1 - 1.6e-12 47.6 0.0 0.0067 16.7 0.0 6.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ41098.1 - 2.9e-06 26.2 0.1 0.15 10.7 0.0 3.5 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KEZ41098.1 - 0.0012 17.5 0.0 0.0024 16.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KEZ41098.1 - 0.057 12.2 0.0 4.4 5.9 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like DASH_Ask1 PF08655.10 KEZ41099.1 - 1.1e-30 105.3 0.2 1.8e-30 104.6 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF5435 PF17503.2 KEZ41099.1 - 0.23 11.2 0.8 0.45 10.2 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Methyltr_RsmB-F PF01189.17 KEZ41100.1 - 4.8e-32 111.2 0.0 3.4e-25 88.9 0.0 2.7 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KEZ41100.1 - 0.0035 17.5 0.0 0.0099 16.0 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase EzrA PF06160.12 KEZ41102.1 - 0.00015 20.1 18.1 0.00015 20.1 18.1 3.0 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 KEZ41102.1 - 0.015 15.5 9.2 0.015 15.5 9.2 6.3 3 3 4 7 7 7 0 ABC transporter C-terminal domain Orthopox_F7 PF05813.12 KEZ41102.1 - 0.086 13.0 1.4 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Orthopoxvirus F7 protein DUF2935 PF11155.8 KEZ41102.1 - 0.09 13.1 6.3 0.07 13.5 0.8 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.10 KEZ41102.1 - 0.64 10.2 38.9 0.3 11.3 4.4 4.5 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family Hemagglutinin PF00509.18 KEZ41102.1 - 1.8 6.9 5.0 2.6 6.3 1.3 2.3 1 1 0 2 2 2 0 Haemagglutinin MtrG PF04210.13 KEZ41102.1 - 2.2 8.2 6.0 13 5.7 0.1 3.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Baculo_PEP_C PF04513.12 KEZ41102.1 - 4.3 7.4 10.7 12 5.9 0.9 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 KEZ41102.1 - 6.3 6.1 51.3 0.82 9.0 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KEZ41102.1 - 6.5 7.3 61.9 0.32 11.5 25.6 5.1 3 2 2 5 5 5 0 Apg6 coiled-coil region DUF4239 PF14023.6 KEZ41102.1 - 7.4 6.2 14.9 0.096 12.4 2.2 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) RNA_pol_Rpb5_C PF01191.19 KEZ41103.1 - 3.9e-33 113.1 0.2 1e-32 111.8 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KEZ41103.1 - 5e-26 91.1 0.1 7.9e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KEZ41103.1 - 0.0007 19.6 0.0 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease Gaa1 PF04114.14 KEZ41104.1 - 1.4 7.9 4.1 2 7.3 4.1 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Epimerase PF01370.21 KEZ41105.1 - 3.4e-08 33.3 0.1 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEZ41105.1 - 5.9e-07 29.6 0.0 3.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KEZ41105.1 - 4.4e-06 27.1 0.0 9.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KEZ41105.1 - 0.0022 17.6 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEZ41105.1 - 0.0061 16.0 0.1 0.51 9.7 0.0 2.4 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ41105.1 - 0.18 10.9 0.0 0.98 8.5 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein TFCD_C PF12612.8 KEZ41106.1 - 2.3e-29 102.6 1.1 7e-29 101.0 1.1 1.9 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 KEZ41106.1 - 0.0011 19.1 5.4 0.29 11.5 0.0 6.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 KEZ41106.1 - 0.067 13.7 4.1 0.96 10.0 0.2 4.7 4 1 0 4 4 4 0 HEAT-like repeat ABC_membrane PF00664.23 KEZ41107.1 - 8.7e-34 117.4 22.8 3.2e-18 66.4 3.8 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ41107.1 - 9.4e-34 116.9 1.4 8.5e-17 62.0 0.0 3.6 2 1 0 2 2 2 2 ABC transporter AAA_23 PF13476.6 KEZ41107.1 - 2.1e-05 25.1 6.7 0.00014 22.4 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KEZ41107.1 - 4.9e-05 23.0 1.7 0.12 12.1 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ41107.1 - 0.00011 22.7 0.3 0.0044 17.4 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ41107.1 - 0.00035 20.5 0.0 0.022 14.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KEZ41107.1 - 0.00055 19.4 9.3 0.8 9.1 0.2 4.0 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ41107.1 - 0.013 15.3 0.8 1.9 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KEZ41107.1 - 0.015 15.5 0.1 7.6 6.9 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KEZ41107.1 - 0.018 14.7 0.0 0.45 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KEZ41107.1 - 0.029 14.7 1.1 1.5 9.1 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF4710 PF15828.5 KEZ41107.1 - 0.037 14.1 2.0 0.088 12.9 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF2075 PF09848.9 KEZ41107.1 - 0.075 12.3 0.1 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.12 KEZ41107.1 - 0.082 12.4 1.0 1 8.8 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein MMR_HSR1 PF01926.23 KEZ41107.1 - 0.13 12.4 1.0 18 5.4 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KEZ41107.1 - 0.15 11.4 0.2 6.3 6.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 KEZ41107.1 - 0.27 11.5 0.6 0.85 9.9 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KEZ41107.1 - 0.32 11.0 3.8 1 9.4 0.0 3.0 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.17 KEZ41107.1 - 2.8 8.0 7.7 0.91 9.6 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain Glycos_transf_2 PF00535.26 KEZ41108.1 - 1.7e-26 93.0 0.0 2.8e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ41108.1 - 6.5e-11 42.6 0.1 4.9e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KEZ41108.1 - 0.0013 18.2 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KEZ41108.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 SMK-1 PF04802.15 KEZ41110.1 - 5.2e-82 274.3 1.6 5.9e-82 274.1 0.2 1.8 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 PMSI1 PF15322.6 KEZ41110.1 - 0.49 9.8 5.8 0.81 9.1 5.8 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative AAA PF00004.29 KEZ41111.1 - 1.5e-49 167.8 0.0 3.5e-36 124.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ41111.1 - 3.1e-12 46.1 4.0 2.2e-10 40.1 0.1 3.6 4 0 0 4 4 4 1 AAA+ lid domain AAA_16 PF13191.6 KEZ41111.1 - 2.7e-08 34.4 3.8 0.028 14.8 0.0 4.3 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 KEZ41111.1 - 2.5e-07 30.6 0.0 0.00023 20.9 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEZ41111.1 - 3.1e-06 27.3 0.0 0.055 13.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEZ41111.1 - 1.2e-05 25.6 0.0 0.075 13.4 0.0 2.9 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.6 KEZ41111.1 - 6.8e-05 23.1 0.0 0.089 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEZ41111.1 - 0.0043 17.3 0.1 2.2 8.5 0.1 3.0 3 0 0 3 3 3 1 AAA domain Vps4_C PF09336.10 KEZ41111.1 - 0.0044 17.0 0.0 2 8.5 0.0 3.6 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KEZ41111.1 - 0.0048 16.7 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 KEZ41111.1 - 0.0055 16.7 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEZ41111.1 - 0.0056 16.3 0.0 0.53 9.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ41111.1 - 0.0071 16.6 0.9 2.2 8.5 0.2 3.6 3 2 0 3 3 2 1 AAA domain Rad17 PF03215.15 KEZ41111.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KEZ41111.1 - 0.012 15.7 0.0 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KEZ41111.1 - 0.036 13.9 0.0 9.5 6.1 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KEZ41111.1 - 0.054 13.5 0.0 9.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEZ41111.1 - 0.067 12.9 0.2 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ41111.1 - 0.077 12.5 0.0 12 5.4 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_17 PF13207.6 KEZ41111.1 - 0.11 12.9 0.3 16 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Torsin PF06309.11 KEZ41111.1 - 0.12 12.5 0.0 0.84 9.7 0.0 2.1 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.6 KEZ41111.1 - 0.2 11.4 0.1 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KEZ41111.1 - 0.46 10.4 2.8 4.6 7.1 0.1 3.1 2 1 1 3 3 3 0 NACHT domain NCA2 PF08637.10 KEZ41112.1 - 2.1e-93 312.7 0.7 3.2e-93 312.1 0.7 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.6 KEZ41112.1 - 0.16 10.9 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Ras PF00071.22 KEZ41113.1 - 7.5e-65 217.5 0.0 8.8e-65 217.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ41113.1 - 6e-34 116.8 0.0 9.4e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ41113.1 - 6.4e-13 48.5 0.0 8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEZ41113.1 - 1.5e-05 24.6 0.0 3.3e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KEZ41113.1 - 0.00026 20.5 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEZ41113.1 - 0.0023 18.0 0.0 0.008 16.3 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ41113.1 - 0.0031 17.4 0.2 2.6 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KEZ41113.1 - 0.039 13.4 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KEZ41113.1 - 0.046 13.2 0.0 0.25 10.8 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.29 KEZ41113.1 - 0.1 13.0 0.0 7.1 7.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ41113.1 - 0.12 12.6 0.1 0.49 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain FA_hydroxylase PF04116.13 KEZ41115.1 - 1.6e-23 83.5 15.5 1.6e-23 83.5 15.5 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily bZIP_1 PF00170.21 KEZ41116.1 - 8.9e-08 32.1 9.9 1.7e-07 31.2 9.9 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEZ41116.1 - 2.6 8.2 12.1 21 5.3 12.1 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Actin PF00022.19 KEZ41117.1 - 9.2e-60 202.4 0.0 2e-34 118.9 0.0 2.3 2 0 0 2 2 2 2 Actin HABP4_PAI-RBP1 PF04774.15 KEZ41117.1 - 3 8.7 22.6 2.4 9.1 9.7 2.8 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family Got1 PF04178.12 KEZ41118.1 - 2e-15 57.2 11.9 2.5e-15 56.9 11.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 KEZ41119.1 - 1.9e-48 163.9 0.0 2.1e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Profilin Sec63 PF02889.16 KEZ41120.1 - 8e-132 438.1 0.0 4e-79 265.4 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KEZ41120.1 - 1.3e-50 171.5 0.2 5.5e-26 91.4 0.2 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 KEZ41120.1 - 4.1e-23 82.2 0.0 9.9e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEZ41120.1 - 9.6e-16 58.1 0.4 2.3e-06 27.9 0.0 4.9 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEZ41120.1 - 1e-06 29.1 0.7 0.073 13.3 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEZ41120.1 - 1.5e-06 28.0 0.0 0.043 13.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 KEZ41120.1 - 4.2e-05 23.7 0.1 0.00021 21.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_19 PF13245.6 KEZ41120.1 - 6.2e-05 23.4 0.3 0.0081 16.5 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEZ41120.1 - 0.0032 17.9 0.0 1.7 9.0 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KEZ41120.1 - 0.082 11.9 0.0 2.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 KEZ41120.1 - 0.18 11.2 1.2 20 4.5 0.1 3.5 4 0 0 4 4 4 0 Bacterial TniB protein Ras PF00071.22 KEZ41121.1 - 1.8e-40 138.2 0.0 3.5e-38 130.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KEZ41121.1 - 8.9e-32 109.8 0.0 1.4e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ41121.1 - 1e-10 41.4 0.0 1.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEZ41121.1 - 0.00027 21.0 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KEZ41121.1 - 0.0089 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KEZ41121.1 - 0.034 14.5 0.0 0.045 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KEZ41121.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 KEZ41121.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FMN_dh PF01070.18 KEZ41122.1 - 3.1e-121 404.6 0.1 3.8e-121 404.4 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEZ41122.1 - 4.5e-22 78.0 0.0 8.8e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KEZ41122.1 - 2e-08 33.8 0.0 3.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEZ41122.1 - 0.00021 20.4 0.9 0.0014 17.7 0.2 2.3 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KEZ41122.1 - 0.0009 18.7 0.1 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase G3P_antiterm PF04309.12 KEZ41122.1 - 0.04 13.3 0.0 0.81 9.1 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 KEZ41122.1 - 0.049 13.1 1.3 2.4 7.6 0.2 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein BRO1 PF03097.18 KEZ41123.1 - 2.1e-134 448.2 0.7 2.1e-134 448.2 0.7 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KEZ41123.1 - 8.9e-76 255.0 21.2 1.7e-75 254.1 21.2 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3012 PF11216.8 KEZ41123.1 - 0.32 11.1 1.6 2.1 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) DnaJ_C PF01556.18 KEZ41124.1 - 1.6e-38 132.1 0.0 2.3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ41124.1 - 3.9e-25 87.7 2.0 8.3e-25 86.7 2.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEZ41124.1 - 6.2e-09 36.1 20.5 1.1e-08 35.3 20.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Forkhead PF00250.18 KEZ41124.1 - 0.042 14.1 0.1 0.077 13.3 0.1 1.4 1 0 0 1 1 1 0 Forkhead domain HypA PF01155.19 KEZ41124.1 - 0.69 10.0 6.5 19 5.3 6.8 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fungal_trans PF04082.18 KEZ41125.1 - 2.4e-68 230.1 0.0 3.3e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEZ41125.1 - 0.00069 19.9 14.8 0.00081 19.7 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ41125.1 - 0.036 14.9 12.0 0.048 14.5 1.5 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEZ41125.1 - 1.6 9.3 13.8 0.4 11.2 3.7 3.1 3 0 0 3 3 3 0 Zinc-finger double domain F-box-like PF12937.7 KEZ41126.1 - 2e-10 40.4 0.0 5.5e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ41126.1 - 1.9e-06 27.6 0.1 5.5e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain 4HBT PF03061.22 KEZ41127.1 - 1.2e-13 51.2 0.1 1.8e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KEZ41127.1 - 2.3e-06 28.1 0.1 3.5e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_hydro_16 PF00722.21 KEZ41128.1 - 1.4e-05 24.7 0.4 2.8e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 ABC_tran PF00005.27 KEZ41129.1 - 3.7e-43 147.3 3.9 1.3e-20 74.3 0.1 3.7 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KEZ41129.1 - 1.2e-10 41.2 0.5 0.1 12.0 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ41129.1 - 2.8e-09 37.2 11.4 0.002 18.0 0.0 5.1 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ41129.1 - 3.7e-08 33.0 0.8 0.0003 20.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KEZ41129.1 - 9e-07 29.0 0.5 0.03 14.4 0.3 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 KEZ41129.1 - 9.1e-07 28.8 3.9 9.1e-07 28.8 3.9 2.2 2 0 0 2 2 1 1 ABC transporter AAA_28 PF13521.6 KEZ41129.1 - 1.4e-06 28.7 1.3 0.004 17.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KEZ41129.1 - 1e-05 26.1 0.0 0.056 14.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KEZ41129.1 - 3.3e-05 23.0 1.7 0.0096 14.9 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KEZ41129.1 - 0.00012 22.0 3.4 0.28 11.1 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase DUF87 PF01935.17 KEZ41129.1 - 0.00013 22.2 7.1 0.097 12.8 0.1 3.2 4 0 0 4 4 3 2 Helicase HerA, central domain NACHT PF05729.12 KEZ41129.1 - 0.0002 21.3 0.1 0.022 14.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ41129.1 - 0.00024 21.4 0.3 1.6 9.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KEZ41129.1 - 0.00041 20.5 1.1 2.2 8.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_27 PF13514.6 KEZ41129.1 - 0.00046 19.8 0.0 0.027 14.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ41129.1 - 0.00061 20.2 4.4 0.89 9.9 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 KEZ41129.1 - 0.0028 17.7 0.4 3.2 7.8 0.0 3.7 5 0 0 5 5 3 1 AAA domain NB-ARC PF00931.22 KEZ41129.1 - 0.0029 16.8 0.7 2.3 7.3 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain DUF815 PF05673.13 KEZ41129.1 - 0.0033 16.6 0.2 2.8 7.0 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA PF00004.29 KEZ41129.1 - 0.0038 17.6 0.0 1.8 9.0 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 KEZ41129.1 - 0.0042 16.5 0.6 0.23 10.9 0.1 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KEZ41129.1 - 0.0043 17.1 0.5 2.3 8.2 0.0 2.8 3 0 0 3 3 2 1 Dynamin family RNA_helicase PF00910.22 KEZ41129.1 - 0.0048 17.3 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 KEZ41129.1 - 0.0051 16.6 0.0 4.7 6.9 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 KEZ41129.1 - 0.0082 16.7 13.6 0.081 13.4 2.2 3.5 3 1 0 3 3 3 2 AAA domain ATP-synt_ab PF00006.25 KEZ41129.1 - 0.012 15.3 0.1 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.17 KEZ41129.1 - 0.013 15.2 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase ATPase_2 PF01637.18 KEZ41129.1 - 0.019 14.9 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KEZ41129.1 - 0.02 14.8 0.4 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 NTPase Roc PF08477.13 KEZ41129.1 - 0.029 14.6 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KEZ41129.1 - 0.031 14.0 3.7 0.19 11.4 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 KEZ41129.1 - 0.034 13.4 2.3 4.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_17 PF13207.6 KEZ41129.1 - 0.044 14.2 8.0 3.9 7.9 0.0 4.4 4 1 0 4 4 4 0 AAA domain TsaE PF02367.17 KEZ41129.1 - 0.056 13.5 0.7 3.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KEZ41129.1 - 0.07 12.8 3.0 4.5 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KEZ41129.1 - 0.071 12.6 0.1 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KEZ41129.1 - 0.082 12.9 0.2 3.4 7.7 0.0 3.2 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KEZ41129.1 - 0.098 12.6 0.2 12 5.8 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KEZ41129.1 - 0.1 12.2 1.3 11 5.5 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 KEZ41129.1 - 0.11 12.2 7.0 2.1 8.0 0.0 3.5 4 1 0 4 4 3 0 AAA domain G-alpha PF00503.20 KEZ41129.1 - 0.14 11.3 1.0 0.66 9.1 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NYN PF01936.18 KEZ41129.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 NYN domain AAA_13 PF13166.6 KEZ41129.1 - 0.33 9.5 6.1 6.7 5.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF3437 PF11919.8 KEZ41130.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) adh_short PF00106.25 KEZ41131.1 - 3.1e-85 284.6 11.3 2.7e-45 154.2 1.1 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41131.1 - 3.7e-69 232.8 7.7 2.6e-37 128.6 1.1 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KEZ41131.1 - 2.6e-34 117.4 0.0 5.3e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KEZ41131.1 - 2.2e-30 105.9 3.5 5.2e-15 55.8 0.2 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 KEZ41131.1 - 0.00015 21.9 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 KEZ41131.1 - 0.00033 20.0 1.0 0.003 16.9 0.4 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 KEZ41131.1 - 0.0025 17.3 1.4 0.15 11.5 0.2 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KEZ41131.1 - 0.22 11.4 8.5 3.4 7.5 1.1 3.2 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAM25 PF15825.5 KEZ41131.1 - 1.3 9.4 7.9 8.3 6.8 1.5 2.9 2 0 0 2 2 2 0 FAM25 family Glucodextran_B PF09136.10 KEZ41131.1 - 6.1 7.3 8.5 0.14 12.6 0.3 2.5 3 0 0 3 3 3 0 Glucodextranase, domain B Acetyltransf_1 PF00583.25 KEZ41132.1 - 0.0081 16.4 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3788 PF12663.7 KEZ41132.1 - 0.057 13.4 0.1 0.096 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) Xpo1 PF08389.12 KEZ41133.1 - 4.9e-27 94.8 2.7 3.5e-26 92.0 0.2 3.7 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 KEZ41133.1 - 1.1e-06 28.4 0.0 4e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 KEZ41133.1 - 0.0069 15.0 0.4 0.7 8.4 0.1 2.6 2 0 0 2 2 2 2 Adaptin N terminal region Tab2_like PF06485.11 KEZ41133.1 - 0.0097 15.4 0.1 0.075 12.5 0.0 2.3 2 0 0 2 2 2 1 RNA-binding protein Tab2/Atab2 Importin_rep_3 PF18806.1 KEZ41133.1 - 0.013 15.5 0.0 9.1 6.4 0.0 3.8 2 1 0 2 2 2 0 Importin 13 repeat DUF2130 PF09903.9 KEZ41133.1 - 0.032 13.5 0.0 0.78 9.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) RVT_N PF13655.6 KEZ41133.1 - 0.037 14.3 0.1 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase CRM1_C PF08767.11 KEZ41133.1 - 0.12 11.6 0.0 0.32 10.1 0.0 1.8 1 0 0 1 1 1 0 CRM1 C terminal 5-FTHF_cyc-lig PF01812.20 KEZ41134.1 - 1e-28 100.4 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.15 KEZ41135.1 - 1.7e-203 677.7 37.2 2e-203 677.5 37.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein APH PF01636.23 KEZ41136.1 - 2.4e-10 40.7 0.0 3.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ41136.1 - 0.00022 20.9 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KEZ41137.1 - 3.7e-39 134.3 0.0 5.3e-27 94.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 KEZ41137.1 - 6.2e-32 109.7 0.0 1.5e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KEZ41137.1 - 7.3e-06 26.1 0.1 0.012 15.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KEZ41137.1 - 0.00023 20.6 0.0 0.013 14.8 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Prothymosin PF03247.14 KEZ41137.1 - 6.6 7.2 15.9 0.15 12.6 9.1 1.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family RPN1_RPN2_N PF17781.1 KEZ41138.1 - 4e-117 391.0 1.1 5.9e-117 390.5 1.1 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KEZ41138.1 - 5.9e-29 99.9 0.1 1e-28 99.1 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KEZ41138.1 - 8.9e-21 73.2 10.7 4.6e-06 26.8 0.1 8.4 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KEZ41138.1 - 1.9e-07 31.3 1.1 0.0044 17.4 0.0 4.7 6 1 1 7 7 7 3 HEAT repeats Zn_clus PF00172.18 KEZ41139.1 - 3.9e-06 26.9 10.8 5.7e-06 26.3 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lon_C PF05362.13 KEZ41140.1 - 7.2e-66 221.6 0.1 1.5e-65 220.6 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KEZ41140.1 - 2.8e-23 82.8 0.0 2.6e-21 76.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 KEZ41140.1 - 7.8e-18 65.1 0.0 1.4e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 KEZ41140.1 - 2.5e-08 34.0 0.0 7.4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KEZ41140.1 - 3.6e-07 30.0 0.0 6.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KEZ41140.1 - 8.9e-06 26.2 2.4 1.5e-05 25.4 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KEZ41140.1 - 7.1e-05 22.6 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KEZ41140.1 - 0.00016 21.4 0.1 0.0007 19.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KEZ41140.1 - 0.00021 21.2 0.0 0.0006 19.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 KEZ41140.1 - 0.0008 19.6 0.0 0.0032 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEZ41140.1 - 0.0013 19.0 0.0 0.061 13.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 KEZ41140.1 - 0.005 16.1 0.4 0.039 13.2 0.1 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 KEZ41140.1 - 0.0099 15.8 0.0 0.044 13.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 KEZ41140.1 - 0.011 16.2 0.0 0.084 13.3 0.0 2.6 3 0 0 3 3 1 0 RNA helicase AAA_18 PF13238.6 KEZ41140.1 - 0.012 16.2 0.0 0.04 14.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 KEZ41140.1 - 0.023 14.6 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 KEZ41140.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 KEZ41140.1 - 0.03 14.2 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KEZ41140.1 - 0.038 14.2 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEZ41140.1 - 0.058 13.3 0.0 0.28 11.1 0.0 2.1 1 1 1 2 2 2 0 NTPase Mg_chelatase PF01078.21 KEZ41140.1 - 0.063 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KEZ41140.1 - 0.065 13.7 0.0 0.065 13.7 0.0 3.2 1 1 1 2 2 1 0 AAA domain AAA_14 PF13173.6 KEZ41140.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ41140.1 - 0.085 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KEZ41140.1 - 0.13 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEZ41140.1 - 0.14 11.9 2.9 0.19 11.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain APG6_N PF17675.1 KEZ41140.1 - 6.6 7.3 11.9 0.43 11.1 6.7 1.8 2 0 0 2 2 1 0 Apg6 coiled-coil region RPA_C PF08784.11 KEZ41141.1 - 1.6e-20 73.7 0.9 5.9e-20 71.9 0.1 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KEZ41141.1 - 4.7e-05 23.3 0.4 0.00019 21.4 0.2 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KEZ41141.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Acetyltransf_1 PF00583.25 KEZ41142.1 - 3.5e-09 36.9 0.0 5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ41142.1 - 4e-08 33.6 0.0 6.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ41142.1 - 5.3e-08 33.0 0.0 8.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ41142.1 - 3.6e-07 30.2 0.0 4.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ41142.1 - 0.00069 19.5 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KEZ41142.1 - 0.023 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NUDIX PF00293.28 KEZ41143.1 - 1.2e-26 93.3 0.0 1.7e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.18 KEZ41144.1 - 1.5e-56 190.5 29.8 1.6e-33 115.7 7.5 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KEZ41144.1 - 1.4e-06 28.5 12.3 1.4e-06 28.5 12.3 3.6 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain LSM PF01423.22 KEZ41145.1 - 8.1e-15 54.3 0.0 1.1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEZ41145.1 - 0.047 13.8 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain MFS_1 PF07690.16 KEZ41146.1 - 4.8e-25 88.2 45.6 2.4e-24 86.0 28.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily GCIP PF13324.6 KEZ41146.1 - 0.013 15.2 2.7 0.02 14.5 2.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting HATPase_c_3 PF13589.6 KEZ41146.1 - 0.025 14.4 1.9 3.9 7.3 0.0 2.3 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2457 PF10446.9 KEZ41146.1 - 0.25 10.5 13.6 0.47 9.5 13.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 KEZ41146.1 - 0.3 10.8 3.5 0.6 9.8 3.5 1.4 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 KEZ41146.1 - 0.63 10.4 15.8 1.9 8.9 15.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 KEZ41146.1 - 2.5 7.8 15.2 3.7 7.2 15.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 KEZ41146.1 - 6.3 6.8 6.0 11 6.1 6.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KEZ41146.1 - 6.6 6.0 14.9 9.2 5.5 14.9 1.1 1 0 0 1 1 1 0 NOA36 protein Homeobox_KN PF05920.11 KEZ41147.1 - 2.2e-16 59.5 1.2 2.2e-16 59.5 1.2 2.6 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 KEZ41147.1 - 6.5e-13 48.5 1.8 9.5e-07 28.8 0.1 4.1 4 1 0 4 4 4 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 KEZ41147.1 - 1.5e-05 24.7 0.4 4.6e-05 23.2 0.4 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 KEZ41147.1 - 4.9e-05 23.6 11.8 0.018 15.5 3.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ41147.1 - 0.0021 18.7 3.7 0.0021 18.7 3.7 4.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ41147.1 - 0.76 10.1 4.6 0.84 10.0 2.8 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 KEZ41147.1 - 1.1 9.5 3.1 11 6.3 0.2 2.6 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KEZ41147.1 - 1.8 9.1 6.4 7.4 7.2 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 KEZ41147.1 - 3.7 8.1 7.4 1.7e+02 2.8 1.5 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type MTHFR PF02219.17 KEZ41148.1 - 2.3e-109 365.2 0.0 3.2e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PWI PF01480.17 KEZ41149.1 - 3.2e-08 33.7 0.1 7.2e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 KEZ41149.1 - 7.4e-08 32.1 0.2 2.6e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 KEZ41149.1 - 3.9e-05 23.4 2.2 7.8e-05 22.5 2.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 KEZ41149.1 - 5.5e-05 23.1 0.0 0.00094 19.1 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Torus PF16131.5 KEZ41149.1 - 0.02 15.6 0.1 0.049 14.3 0.1 1.6 1 0 0 1 1 1 0 Torus domain GTP_EFTU PF00009.27 KEZ41150.1 - 4.4e-66 222.1 0.2 6.2e-66 221.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KEZ41150.1 - 8e-34 116.0 0.0 3.2e-33 114.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KEZ41150.1 - 5.3e-22 77.7 0.0 1.3e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEZ41150.1 - 8.5e-13 48.5 0.3 3.3e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KEZ41150.1 - 7.7e-12 45.1 0.0 2.7e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KEZ41150.1 - 7.9e-06 25.9 0.2 1.8e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sulfatase PF00884.23 KEZ41150.1 - 0.045 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Sulfatase Solute_trans_a PF03619.16 KEZ41152.1 - 3.9e-84 282.3 11.9 2.8e-83 279.5 11.9 1.9 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_92 PF07971.12 KEZ41153.1 - 3.2e-137 458.2 0.1 3.9e-137 457.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KEZ41153.1 - 5.2e-52 177.1 0.4 8.9e-52 176.4 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Not1 PF04054.15 KEZ41153.1 - 0.12 11.2 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 Fungal_trans PF04082.18 KEZ41154.1 - 2.3e-16 59.6 0.2 6.1e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ41155.1 - 4.4e-45 154.2 35.2 4.4e-45 154.2 35.2 1.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ41155.1 - 6.7e-13 48.3 21.3 3.2e-12 46.1 21.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KEZ41155.1 - 0.00011 21.6 8.4 0.00011 21.6 8.4 2.6 1 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KEZ41155.1 - 0.0014 17.1 14.8 0.23 9.8 14.5 2.3 1 1 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KEZ41155.1 - 2.4 6.3 16.0 5.1 5.3 7.1 3.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 KEZ41156.1 - 0.017 15.3 7.0 0.036 14.2 7.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec5 PF15469.6 KEZ41157.1 - 9.7e-36 123.4 0.0 2.5e-35 122.0 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 KEZ41157.1 - 0.00018 21.5 1.7 0.0016 18.5 0.1 2.8 2 0 0 2 2 2 1 Vps51/Vps67 HEPN_SAV2148 PF18725.1 KEZ41157.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 SAV2148-like HEPN Sec15 PF04091.12 KEZ41157.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like LRR_9 PF14580.6 KEZ41158.1 - 2.7e-34 118.2 0.3 9.9e-21 74.0 0.0 2.4 2 1 1 3 3 3 2 Leucine-rich repeat DUF4349 PF14257.6 KEZ41158.1 - 5.7e-05 22.7 0.1 8.8e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_4 PF12799.7 KEZ41158.1 - 0.041 14.3 0.1 0.18 12.3 0.1 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) PspB PF06667.12 KEZ41158.1 - 0.098 12.7 1.8 0.22 11.6 1.8 1.6 1 0 0 1 1 1 0 Phage shock protein B CBFD_NFYB_HMF PF00808.23 KEZ41159.1 - 2e-12 47.2 0.2 3.8e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.20 KEZ41160.1 - 1.5e-88 297.4 28.3 1.5e-88 297.4 28.3 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KEZ41160.1 - 1.4e-12 47.8 0.1 1.6e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain ASCH PF04266.14 KEZ41160.1 - 0.04 14.5 0.1 0.093 13.3 0.1 1.5 1 0 0 1 1 1 0 ASCH domain EamA PF00892.20 KEZ41161.1 - 0.00013 22.2 9.4 0.00095 19.4 4.1 2.1 1 1 1 2 2 2 2 EamA-like transporter family Trp_oprn_chp PF09534.10 KEZ41161.1 - 0.0013 18.5 0.4 0.33 10.7 0.0 2.1 1 1 1 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AAA_22 PF13401.6 KEZ41162.1 - 3.9e-08 33.7 0.0 1.4e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ41162.1 - 6e-08 33.3 0.0 4.5e-07 30.4 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KEZ41162.1 - 3e-06 27.3 0.0 8.7e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KEZ41162.1 - 0.001 19.6 0.0 0.0042 17.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 KEZ41162.1 - 0.024 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 KEZ41162.1 - 0.035 13.3 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 KEZ41162.1 - 0.045 14.3 0.3 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ41162.1 - 0.067 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEZ41162.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KEZ41162.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SesA PF17107.5 KEZ41162.1 - 0.098 12.8 1.3 2 8.6 0.4 2.7 2 1 0 2 2 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_29 PF13555.6 KEZ41162.1 - 0.14 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KEZ41162.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TFIIA_gamma_N PF02268.16 KEZ41163.1 - 6.6e-25 86.9 0.3 9.1e-25 86.4 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KEZ41163.1 - 1.8e-23 82.4 0.6 2.7e-23 81.8 0.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF570 PF04489.13 KEZ41163.1 - 0.1 11.2 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF570) ATP-synt_C PF00137.21 KEZ41164.1 - 1.2e-23 83.2 33.9 2.7e-16 59.6 9.6 2.9 3 1 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KEZ41164.1 - 0.086 12.2 0.3 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2427 PF10348.9 KEZ41164.1 - 0.24 11.2 2.0 3.8 7.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) MIG-14_Wnt-bd PF06664.12 KEZ41164.1 - 1.2 8.3 5.3 0.54 9.4 1.5 1.9 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF2165 PF09933.9 KEZ41164.1 - 8.6 6.4 9.0 3.6 7.6 1.2 2.8 2 1 1 3 3 3 0 Predicted small integral membrane protein (DUF2165) MoCF_biosynth PF00994.24 KEZ41165.1 - 2.3e-45 153.8 0.7 4e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KEZ41165.1 - 8.5e-39 132.8 2.6 1.4e-38 132.2 2.6 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KEZ41165.1 - 2.6e-15 56.4 0.0 1.2e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) RNase_P_Rpp14 PF01900.19 KEZ41166.1 - 9.3e-23 80.4 0.2 1.2e-22 80.1 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 KEZ41167.1 - 2.5e-47 161.7 0.0 2.8e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KEZ41167.1 - 0.00054 19.0 0.0 0.00067 18.7 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KEZ41167.1 - 0.0044 17.0 0.0 1.1 9.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEZ41167.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KEZ41167.1 - 0.039 14.1 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEZ41167.1 - 0.14 12.5 0.3 0.33 11.4 0.2 1.6 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 KEZ41167.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 KEZ41167.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MipZ PF09140.11 KEZ41167.1 - 0.25 10.6 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ cNMP_binding PF00027.29 KEZ41168.1 - 1.7e-27 95.3 0.0 4.9e-15 55.4 0.0 5.1 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 KEZ41168.1 - 6.7e-17 62.3 3.3 1.5e-12 48.1 2.8 2.6 2 0 0 2 2 2 2 Patatin-like phospholipase Pyridoxal_deC PF00282.19 KEZ41169.1 - 8.1e-104 347.3 0.0 9.7e-104 347.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KEZ41169.1 - 0.0024 17.2 0.0 0.0092 15.3 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase EMP70 PF02990.16 KEZ41170.1 - 6.5e-204 678.4 0.0 8e-204 678.1 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Zip PF02535.22 KEZ41171.1 - 1e-57 195.9 12.8 2.2e-57 194.8 12.8 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2157 PF09925.9 KEZ41171.1 - 0.94 9.3 5.1 2.5 7.9 0.6 3.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Glyco_hydro_17 PF00332.18 KEZ41172.1 - 4.6e-10 39.6 0.1 6.6e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Hamartin PF04388.12 KEZ41173.1 - 1.7e-23 83.3 6.8 1.7e-23 83.3 6.8 4.1 2 2 1 3 3 3 2 Hamartin protein Sec7_N PF12783.7 KEZ41173.1 - 0.026 14.4 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Tuberin PF03542.16 KEZ41173.1 - 0.067 12.3 0.1 0.17 11.0 0.1 1.6 1 0 0 1 1 1 0 Tuberin DUF447 PF04289.12 KEZ41173.1 - 0.13 12.1 1.0 0.26 11.0 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF447) DUF1664 PF07889.12 KEZ41173.1 - 0.89 9.6 8.3 0.34 11.0 1.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DJ-1_PfpI PF01965.24 KEZ41174.1 - 1.9e-10 40.8 0.0 3.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KEZ41174.1 - 0.036 13.8 0.0 0.056 13.1 0.0 1.3 1 1 0 1 1 1 0 ThiJ/PfpI family-like Methyltransf_2 PF00891.18 KEZ41175.1 - 3e-12 46.3 0.0 6.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 KEZ41175.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 KEZ41175.1 - 0.043 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Methyltransf_25 PF13649.6 KEZ41175.1 - 0.052 14.2 0.0 0.24 12.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 KEZ41175.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 KEZ41175.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain HTH_26 PF13443.6 KEZ41175.1 - 0.15 12.6 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain p450 PF00067.22 KEZ41176.1 - 1.2e-52 179.3 0.0 1.5e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KEZ41179.1 - 2.7e-21 76.1 0.0 3.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41179.1 - 1.6e-08 34.2 0.0 2.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L23 PF00276.20 KEZ41180.1 - 3.3e-10 40.2 0.0 6.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Mito_carr PF00153.27 KEZ41181.1 - 1.1e-62 208.0 5.0 1.5e-22 79.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEZ41181.1 - 0.004 16.4 1.1 3.6 6.7 0.0 3.1 3 0 0 3 3 3 2 Gammaproteobacterial serine protease ORC4_C PF14629.6 KEZ41182.1 - 2.4e-64 216.7 0.0 3.5e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KEZ41182.1 - 1.2e-11 45.3 0.0 3.9e-11 43.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain PHD PF00628.29 KEZ41182.1 - 7.9e-11 41.7 7.6 1.3e-10 41.0 7.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KEZ41182.1 - 7.1e-08 31.9 2.7 1.5e-07 30.8 2.7 1.6 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 KEZ41182.1 - 1.8e-06 28.4 0.0 4.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ41182.1 - 6e-06 26.6 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEZ41182.1 - 0.00021 20.5 0.2 0.00045 19.4 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 KEZ41182.1 - 0.00028 20.2 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.12 KEZ41182.1 - 0.00068 19.6 0.1 0.0035 17.3 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KEZ41182.1 - 0.0017 18.7 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ41182.1 - 0.002 17.3 0.2 0.0035 16.6 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain C1_1 PF00130.22 KEZ41182.1 - 0.0067 16.3 0.3 0.015 15.1 0.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 KEZ41182.1 - 0.0093 16.2 0.8 0.021 15.1 0.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger ABC_tran PF00005.27 KEZ41182.1 - 0.013 16.0 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KEZ41182.1 - 0.024 14.1 0.1 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KEZ41182.1 - 0.026 14.2 0.1 0.068 12.8 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 KEZ41182.1 - 0.03 14.0 0.1 0.076 12.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KEZ41182.1 - 0.045 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea zf-RRPl_C4 PF17026.5 KEZ41182.1 - 0.057 13.5 1.9 0.11 12.7 1.9 1.4 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type AAA_14 PF13173.6 KEZ41182.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KEZ41182.1 - 0.13 12.1 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Sugar-bind PF04198.13 KEZ41182.1 - 0.14 11.3 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain ORC2 PF04084.14 KEZ41182.1 - 0.18 10.7 0.7 3.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 2 C1_2 PF03107.16 KEZ41182.1 - 4.2 7.8 6.2 0.48 10.8 1.7 1.7 2 0 0 2 2 1 0 C1 domain Prok-RING_1 PF14446.6 KEZ41182.1 - 5.6 7.0 8.4 0.96 9.4 4.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RGS PF00615.19 KEZ41183.1 - 1.9e-37 128.1 0.1 7.4e-37 126.2 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KEZ41183.1 - 1.9e-24 85.5 0.0 6.5e-19 67.8 0.0 3.4 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 KEZ41183.1 - 0.017 15.2 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Replication-relaxation CDC73_C PF05179.14 KEZ41184.1 - 1.4e-55 187.2 0.0 2.3e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal PfkB PF00294.24 KEZ41185.1 - 6e-59 199.8 0.1 7.6e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KEZ41185.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Bystin PF05291.11 KEZ41186.1 - 1.8e-119 398.3 0.0 2.4e-119 398.0 0.0 1.1 1 0 0 1 1 1 1 Bystin PYRIN PF02758.16 KEZ41186.1 - 0.055 13.6 0.1 0.33 11.1 0.1 2.2 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain PSK_trans_fac PF07704.11 KEZ41186.1 - 0.57 11.0 4.4 0.44 11.3 0.5 2.6 2 0 0 2 2 2 0 Rv0623-like transcription factor DUF383 PF04063.14 KEZ41187.1 - 3.8e-67 225.7 0.8 2.8e-66 222.8 0.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KEZ41187.1 - 5.7e-21 74.1 0.3 1.4e-20 72.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Hid1 PF12722.7 KEZ41187.1 - 0.049 11.8 0.2 0.08 11.1 0.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NTP_transf_9 PF04248.12 KEZ41188.1 - 1.9e-31 107.8 0.5 2.1e-31 107.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) RSN1_7TM PF02714.15 KEZ41189.1 - 2.3e-75 253.4 22.6 2.3e-75 253.4 22.6 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEZ41189.1 - 6.8e-44 149.4 0.2 6.8e-44 149.4 0.2 3.3 2 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEZ41189.1 - 3.3e-31 108.9 6.4 4.1e-18 66.2 0.3 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KEZ41189.1 - 1e-15 57.7 0.0 2.8e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MGC-24 PF05283.11 KEZ41189.1 - 0.95 9.9 5.0 2.2 8.7 5.0 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RIFIN PF02009.16 KEZ41189.1 - 6.9 6.5 8.2 0.61 9.9 0.9 2.3 2 0 0 2 2 2 0 Rifin FAD_binding_3 PF01494.19 KEZ41190.1 - 7.9e-16 58.2 0.0 3.3e-15 56.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ41190.1 - 1.4e-05 25.2 0.3 3e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ41190.1 - 0.00084 18.7 0.0 0.0038 16.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ41190.1 - 0.001 18.8 3.5 0.0021 17.7 1.1 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ41190.1 - 0.0088 15.2 0.8 0.016 14.3 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEZ41190.1 - 0.16 11.2 0.3 0.28 10.4 0.3 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KEZ41190.1 - 0.18 11.0 0.2 0.33 10.2 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KEZ41192.1 - 4.6e-40 137.8 0.0 3.7e-39 134.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.26 KEZ41194.1 - 3.3e-07 30.0 0.6 5.4e-07 29.3 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ccdc124 PF06244.12 KEZ41195.1 - 2.5e-27 95.9 14.2 2.5e-27 95.9 14.2 2.0 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 MFS_1 PF07690.16 KEZ41196.1 - 6.5e-39 133.8 17.5 2.6e-37 128.6 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ41196.1 - 1.8e-10 40.3 4.0 1.8e-10 40.3 4.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 KEZ41197.1 - 2.7e-32 111.9 0.0 4.3e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41197.1 - 0.13 12.4 0.5 0.22 11.6 0.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 KEZ41197.1 - 8.2 6.6 11.6 35 4.6 11.6 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 KEZ41198.1 - 4.9e-16 58.8 0.9 0.011 16.5 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41198.1 - 3.2e-05 24.2 0.0 3 8.2 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain FYVE PF01363.21 KEZ41199.1 - 3.7e-06 27.0 26.4 0.011 15.9 3.7 3.3 3 0 0 3 3 3 3 FYVE zinc finger Zn_ribbon_17 PF17120.5 KEZ41199.1 - 0.004 16.7 30.1 0.028 14.0 3.4 3.3 3 0 0 3 3 3 2 Zinc-ribbon, C4HC2 type FYVE_2 PF02318.16 KEZ41199.1 - 0.018 15.3 26.6 0.44 10.8 0.7 3.8 4 0 0 4 4 4 0 FYVE-type zinc finger zf-ribbon_3 PF13248.6 KEZ41199.1 - 0.029 13.8 1.5 0.029 13.8 1.5 4.8 4 2 0 4 4 4 0 zinc-ribbon domain DUF3470 PF11953.8 KEZ41199.1 - 0.16 12.0 0.3 0.4 10.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) zf-C2H2_6 PF13912.6 KEZ41199.1 - 0.69 10.0 18.5 6.8 6.8 0.5 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger Clr2_transil PF16761.5 KEZ41200.1 - 1.7e-07 32.0 1.7 4.9e-07 30.5 1.7 1.8 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KEZ41200.1 - 0.0012 19.7 5.6 0.0037 18.0 0.0 3.5 3 1 1 4 4 4 1 Transcription-silencing protein Clr2 SR-25 PF10500.9 KEZ41201.1 - 0.022 14.4 9.4 0.034 13.7 1.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 KEZ41201.1 - 6.8 6.7 5.9 30 4.6 0.2 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SPRY PF00622.28 KEZ41202.1 - 0.00029 20.9 0.0 0.0017 18.5 0.0 2.3 3 0 0 3 3 3 1 SPRY domain Mito_carr PF00153.27 KEZ41203.1 - 7.5e-60 198.9 0.1 4.7e-20 71.3 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.23 KEZ41203.1 - 0.0001 22.1 0.0 0.00034 20.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase S24-like EIF_2_alpha PF07541.12 KEZ41204.1 - 1.6e-37 128.1 0.0 3.8e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KEZ41204.1 - 2.7e-13 50.1 0.7 2.7e-13 50.1 0.7 1.7 2 0 0 2 2 2 1 S1 RNA binding domain F-box-like PF12937.7 KEZ41205.1 - 8.3e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ41205.1 - 2e-08 33.9 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain MSA-2c PF12238.8 KEZ41205.1 - 8.7 6.3 7.8 20 5.1 7.8 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Asp PF00026.23 KEZ41206.1 - 3.5e-08 33.2 0.1 2.5e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.15 KEZ41206.1 - 2.6e-06 27.1 2.3 5.4e-06 26.1 2.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 KEZ41206.1 - 0.003 17.8 0.2 0.0082 16.4 0.0 1.9 2 0 0 2 2 2 1 Glycophorin A Mid2 PF04478.12 KEZ41206.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 KEZ41206.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 KEZ41206.1 - 0.15 13.0 0.2 0.35 11.8 0.2 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KEZ41206.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless Shisa PF13908.6 KEZ41206.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator FAD_binding_1 PF00667.20 KEZ41207.1 - 1e-31 110.3 0.0 1.5e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEZ41207.1 - 3.4e-29 101.9 0.0 5.7e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEZ41207.1 - 6.6e-07 30.0 0.0 1.1e-05 26.1 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KEZ41207.1 - 0.05 13.8 0.0 0.59 10.4 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain Flavodoxin_3 PF12641.7 KEZ41207.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain RRM_1 PF00076.22 KEZ41208.1 - 1.2e-31 108.4 0.1 1.7e-14 53.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ41208.1 - 0.00016 21.2 0.0 0.12 11.9 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ41208.1 - 0.0021 18.1 0.0 0.64 10.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 KEZ41208.1 - 0.049 13.9 0.0 40 4.4 0.0 3.2 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 KEZ41208.1 - 0.058 13.5 0.3 4.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 FXMRP1_C_core PF12235.8 KEZ41208.1 - 0.06 14.0 13.3 0.039 14.6 10.3 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DbpA PF03880.15 KEZ41208.1 - 0.066 13.2 0.2 9.2 6.3 0.1 2.7 3 0 0 3 3 3 0 DbpA RNA binding domain ArfGap PF01412.18 KEZ41209.1 - 6.2e-31 106.9 0.1 1.3e-30 105.9 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CPSase_sm_chain PF00988.22 KEZ41210.1 - 5.4e-47 158.8 0.0 8.7e-47 158.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KEZ41210.1 - 1.3e-46 158.8 0.0 1.7e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEZ41210.1 - 1.2e-05 25.1 0.1 0.00088 19.1 0.1 2.5 1 1 0 2 2 2 1 Peptidase C26 ETF PF01012.21 KEZ41211.1 - 2.7e-44 151.2 0.5 3.5e-44 150.8 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Clr5 PF14420.6 KEZ41213.1 - 1.2e-14 54.3 2.3 3.2e-14 52.9 2.3 1.8 1 0 0 1 1 1 1 Clr5 domain Kinesin PF00225.23 KEZ41216.1 - 6.3e-110 367.2 1.1 1.9e-109 365.6 1.1 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ41216.1 - 1.5e-25 89.9 0.1 5.2e-25 88.1 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding CENP-F_leu_zip PF10473.9 KEZ41216.1 - 0.16 12.0 74.2 0.3 11.1 23.9 5.2 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KEZ41216.1 - 0.47 10.0 62.7 0.51 9.9 14.0 4.4 4 1 1 5 5 5 0 Intermediate filament protein UQ_con PF00179.26 KEZ41217.1 - 1.9e-52 176.6 0.1 2.2e-52 176.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ41217.1 - 0.00046 19.9 0.0 0.00052 19.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KEZ41217.1 - 0.031 14.6 0.1 0.042 14.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 KEZ41218.1 - 5.1e-89 298.1 0.8 8.1e-89 297.4 0.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ41218.1 - 1.8e-37 127.7 0.7 5.5e-37 126.2 0.7 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEZ41218.1 - 0.00015 21.4 0.8 0.00027 20.6 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PCI PF01399.27 KEZ41218.1 - 0.027 15.0 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 PCI domain ACP_syn_III PF08545.10 KEZ41218.1 - 2.1 8.2 5.8 17 5.4 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SUN PF03856.13 KEZ41219.1 - 3.7e-76 255.8 6.2 4.7e-76 255.5 6.2 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Plasmodium_Vir PF05795.11 KEZ41219.1 - 5.1 6.4 5.3 6.6 6.0 5.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Cupin_1 PF00190.22 KEZ41220.1 - 3.4e-15 56.0 0.1 5.5e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KEZ41220.1 - 0.038 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain GTP_EFTU PF00009.27 KEZ41221.1 - 1.7e-52 177.8 0.0 2.6e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KEZ41221.1 - 8.6e-23 80.2 0.0 1.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KEZ41221.1 - 7.2e-16 58.0 0.1 1.6e-07 31.2 0.0 3.2 3 0 0 3 3 3 2 Elongation factor G C-terminus RF3_C PF16658.5 KEZ41221.1 - 0.00035 20.4 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KEZ41221.1 - 0.014 15.2 0.0 0.04 13.7 0.0 1.8 1 0 0 1 1 1 0 Elongation factor G, domain IV DUF3794 PF12673.7 KEZ41221.1 - 0.16 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3794) COPI_assoc PF08507.10 KEZ41222.1 - 2.3e-30 105.3 3.8 2.6e-30 105.2 3.8 1.0 1 0 0 1 1 1 1 COPI associated protein GATA PF00320.27 KEZ41223.1 - 3.4e-29 100.1 16.9 6.8e-15 54.4 2.6 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KEZ41223.1 - 0.00025 20.5 4.4 0.033 13.7 0.4 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KEZ41223.1 - 0.00028 21.0 1.5 0.39 10.8 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 KEZ41223.1 - 0.0031 17.6 5.7 0.22 11.7 0.7 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 KEZ41223.1 - 0.0091 15.9 5.9 0.04 13.8 1.1 2.6 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KEZ41223.1 - 0.017 15.3 7.8 0.91 9.7 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-CHY PF05495.12 KEZ41223.1 - 0.082 13.4 4.9 0.9 10.1 1.2 2.5 2 0 0 2 2 2 0 CHY zinc finger TDP43_N PF18694.1 KEZ41223.1 - 0.2 11.5 0.2 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain eIF-5_eIF-2B PF01873.17 KEZ41223.1 - 0.22 11.4 4.9 5.5 6.9 0.4 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 VGCC_beta4Aa_N PF12052.8 KEZ41223.1 - 0.87 9.7 8.4 0.45 10.6 4.7 2.2 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal zf-RRN7 PF11781.8 KEZ41223.1 - 1.1 9.1 8.0 0.42 10.3 0.1 2.9 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 KEZ41223.1 - 4.1 7.5 15.5 2.1 8.5 1.7 3.2 1 1 2 3 3 3 0 Double zinc ribbon LCM PF04072.14 KEZ41224.1 - 1.4e-21 77.3 0.0 3.6e-21 76.0 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.16 KEZ41225.1 - 1.5e-27 95.4 1.6 6.4e-27 93.4 0.1 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit FUSC_2 PF13515.6 KEZ41226.1 - 2.8e-06 27.5 14.3 2.8e-06 27.5 14.3 3.2 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 KEZ41226.1 - 5.3e-06 25.8 1.4 5.3e-06 25.8 1.4 3.6 3 1 2 5 5 5 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 KEZ41226.1 - 1.1 8.0 22.4 0.1 11.4 0.1 3.6 3 1 1 4 4 4 0 Aluminium activated malate transporter Clat_adaptor_s PF01217.20 KEZ41227.1 - 3.8e-43 146.8 1.4 4.1e-43 146.7 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.7 KEZ41228.1 - 1.8e-53 178.5 0.0 3.7e-35 119.8 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KEZ41228.1 - 8.8e-24 85.1 0.5 7.7e-21 75.6 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KEZ41228.1 - 5.8e-15 55.4 0.1 4.6e-05 23.7 0.0 4.6 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 KEZ41228.1 - 5.5e-14 51.7 0.0 5.5e-05 22.9 0.1 4.2 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KEZ41228.1 - 1.5e-09 38.1 0.0 0.00017 21.9 0.0 3.8 3 0 0 3 3 3 2 PDZ domain Peptidase_S46 PF10459.9 KEZ41228.1 - 0.0029 16.3 0.0 0.005 15.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase S46 4HPAD_g_N PF18671.1 KEZ41228.1 - 0.0042 16.8 0.0 0.037 13.7 0.0 2.5 2 0 0 2 2 2 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Tricorn_PDZ PF14685.6 KEZ41228.1 - 0.0053 16.7 0.7 2.3 8.2 0.2 4.3 5 0 0 5 5 5 1 Tricorn protease PDZ domain FliMN_C PF01052.20 KEZ41228.1 - 0.037 14.0 0.9 0.1 12.6 0.9 1.7 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term DUF31 PF01732.16 KEZ41228.1 - 0.082 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Myb_DNA-binding PF00249.31 KEZ41229.1 - 0.0042 17.3 2.1 0.0071 16.5 2.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain MCM2_N PF12619.8 KEZ41229.1 - 0.021 15.1 0.9 0.03 14.6 0.9 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 DnaJ PF00226.31 KEZ41230.1 - 2.4e-18 66.0 0.2 4.7e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain CUE PF02845.16 KEZ41231.1 - 2e-11 43.4 0.0 3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain TFIIA PF03153.13 KEZ41231.1 - 0.064 13.2 4.3 0.077 13.0 4.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G2BR PF18442.1 KEZ41231.1 - 0.078 12.6 7.6 0.19 11.4 7.6 1.6 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) NOT2_3_5 PF04153.18 KEZ41232.1 - 7.2e-30 103.8 0.5 1.1e-29 103.2 0.5 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.19 KEZ41233.1 - 4.3e-49 166.5 0.3 6.4e-49 165.9 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KEZ41233.1 - 4.3e-06 26.7 0.0 0.056 13.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 KEZ41233.1 - 5.6e-05 23.0 0.0 0.00037 20.4 0.0 2.2 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KEZ41233.1 - 0.00012 21.6 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 KEZ41233.1 - 0.00027 21.5 1.1 0.00098 19.7 0.1 2.0 1 1 0 2 2 2 1 AAA domain MeaB PF03308.16 KEZ41233.1 - 0.0011 18.0 0.5 1.8 7.5 0.0 3.0 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 KEZ41233.1 - 0.0012 18.7 0.5 0.0079 16.0 0.5 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KEZ41233.1 - 0.0023 18.2 0.5 0.33 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 KEZ41233.1 - 0.0032 16.8 0.4 0.73 9.1 0.0 2.4 2 0 0 2 2 2 2 Septin AAA_16 PF13191.6 KEZ41233.1 - 0.0039 17.6 0.0 0.042 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KEZ41233.1 - 0.0081 15.9 0.2 0.19 11.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEZ41233.1 - 0.009 16.1 0.0 0.034 14.2 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KEZ41233.1 - 0.03 14.1 0.1 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KEZ41233.1 - 0.045 12.8 0.4 0.23 10.5 0.0 2.1 2 1 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 KEZ41233.1 - 0.053 12.8 0.0 0.74 9.1 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 KEZ41233.1 - 0.071 13.1 0.1 0.18 11.8 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1_Xtn PF16897.5 KEZ41233.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 KEZ41233.1 - 0.1 13.1 0.5 0.45 11.1 0.1 2.3 3 0 0 3 3 3 0 AAA domain Mob1_phocein PF03637.17 KEZ41234.1 - 3.6e-22 79.2 0.6 5.8e-22 78.5 0.6 1.2 1 0 0 1 1 1 1 Mob1/phocein family FbpA PF05833.11 KEZ41234.1 - 0.017 13.9 0.1 0.03 13.1 0.1 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) CxC6 PF18721.1 KEZ41234.1 - 0.029 14.6 2.2 0.059 13.6 2.2 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Fungal_trans_2 PF11951.8 KEZ41235.1 - 9.6e-12 44.4 0.1 3e-11 42.7 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41235.1 - 5.9e-07 29.5 10.9 1.2e-06 28.6 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoD_N PF16655.5 KEZ41235.1 - 0.024 15.2 0.0 0.097 13.2 0.0 2.0 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain Pkinase_fungal PF17667.1 KEZ41236.1 - 2.5e-107 359.2 0.0 3.5e-107 358.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KEZ41236.1 - 0.022 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KEZ41236.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family MOSC PF03473.17 KEZ41237.1 - 1.3e-23 83.4 0.0 2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KEZ41237.1 - 4.3e-14 52.4 0.0 2.4e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain SMC_N PF02463.19 KEZ41238.1 - 4.2e-68 229.1 10.5 6e-67 225.3 10.5 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEZ41238.1 - 3.8e-21 75.6 0.4 3.8e-21 75.6 0.4 3.0 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEZ41238.1 - 1.9e-11 44.3 0.5 0.00016 21.6 0.2 3.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ41238.1 - 6.3e-05 23.6 34.7 6.3e-05 23.6 34.7 7.0 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 KEZ41238.1 - 0.00014 21.6 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 KEZ41238.1 - 0.0037 16.8 16.8 0.0037 16.8 16.8 6.5 2 2 4 7 7 7 2 Mechanosensitive ion channel porin domain HSBP1 PF06825.12 KEZ41238.1 - 6 6.8 14.4 5.1 7.0 0.1 4.6 5 0 0 5 5 5 0 Heat shock factor binding protein 1 INCENP_ARK-bind PF03941.15 KEZ41239.1 - 5.8e-22 77.4 2.2 5.8e-22 77.4 2.2 3.4 4 0 0 4 4 4 1 Inner centromere protein, ARK binding region DEAD PF00270.29 KEZ41241.1 - 5e-40 137.1 0.0 9.5e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ41241.1 - 1.7e-21 76.6 0.1 8.4e-21 74.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KEZ41241.1 - 6.4e-06 25.6 0.1 1.3e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KEZ41241.1 - 0.0087 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEZ41241.1 - 0.062 13.6 0.2 0.24 11.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 KEZ41242.1 - 0.00024 21.8 0.5 1.4 9.9 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41242.1 - 0.087 13.1 0.1 0.6 10.4 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain 2OG-FeII_Oxy_2 PF13532.6 KEZ41243.1 - 1.4e-36 126.6 0.0 1.8e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KEZ41243.1 - 2.4e-08 33.9 7.5 4.2e-08 33.2 7.5 1.4 1 0 0 1 1 1 1 GRF zinc finger GFA PF04828.14 KEZ41244.1 - 2.1e-11 44.0 2.2 4.6e-06 26.9 0.0 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 KEZ41244.1 - 0.0034 17.5 3.5 1.6 9.0 1.7 2.9 2 1 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like RNA_POL_M_15KD PF02150.16 KEZ41244.1 - 0.054 13.4 2.3 6 6.8 0.1 2.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit A2L_zn_ribbon PF08792.10 KEZ41244.1 - 0.51 10.1 0.0 0.51 10.1 0.0 4.1 6 0 0 6 6 6 0 A2L zinc ribbon domain zf-CSL PF05207.13 KEZ41244.1 - 5.8 6.7 12.7 0.61 9.9 0.6 3.1 4 0 0 4 4 4 0 CSL zinc finger Aldo_ket_red PF00248.21 KEZ41246.1 - 2.3e-50 171.5 0.0 2.8e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.11 KEZ41246.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ACPS PF01648.20 KEZ41247.1 - 2.9e-11 43.5 0.0 3.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KEZ41247.1 - 0.00015 21.8 2.3 0.0014 18.7 2.3 2.2 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain DUF1774 PF08611.10 KEZ41248.1 - 2.3e-32 111.2 1.1 2.3e-32 111.2 1.1 2.5 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Clr5 PF14420.6 KEZ41249.1 - 2.1e-06 27.8 0.0 4.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain AAA_6 PF12774.7 KEZ41250.1 - 2.3e-126 421.2 0.0 8.8e-126 419.3 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 KEZ41250.1 - 1.9e-119 399.9 2.9 1.9e-119 399.9 2.9 4.8 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 KEZ41250.1 - 1.9e-119 399.3 4.3 1.9e-119 399.3 4.3 5.5 6 1 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KEZ41250.1 - 1.3e-75 253.3 1.5 1.4e-74 249.9 1.9 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 KEZ41250.1 - 1.4e-66 224.5 0.0 2.3e-65 220.5 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 MT PF12777.7 KEZ41250.1 - 2.7e-43 148.3 8.6 5.3e-43 147.4 8.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 KEZ41250.1 - 1.2e-40 139.0 0.0 6e-36 123.6 0.0 4.6 5 0 0 5 5 4 1 P-loop containing dynein motor region AAA_5 PF07728.14 KEZ41250.1 - 5.4e-32 110.7 0.1 1.2e-10 41.5 0.0 6.8 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 KEZ41250.1 - 9.3e-30 103.6 0.0 2.1e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KEZ41250.1 - 2.5e-29 101.8 0.0 9.8e-27 93.4 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KEZ41250.1 - 2.7e-14 53.6 0.0 0.0076 16.5 0.0 6.4 6 0 0 6 6 4 3 AAA domain Dynein_AAA_lid PF17852.1 KEZ41250.1 - 1.3e-13 51.2 0.0 5.3e-13 49.2 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KEZ41250.1 - 3.2e-13 50.3 0.0 0.0015 19.0 0.0 4.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ41250.1 - 2.6e-09 37.4 1.0 0.46 10.6 0.1 5.3 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 KEZ41250.1 - 5.1e-09 36.8 0.7 0.027 15.0 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 KEZ41250.1 - 3.6e-08 34.0 2.5 1.8 8.9 0.0 7.4 6 0 0 6 6 6 1 AAA ATPase domain T2SSE PF00437.20 KEZ41250.1 - 2.2e-05 23.7 0.0 0.014 14.5 0.0 3.1 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 KEZ41250.1 - 3.5e-05 23.5 0.1 2.3 8.0 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 KEZ41250.1 - 8.6e-05 22.7 0.0 0.00056 20.1 0.0 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KEZ41250.1 - 0.00028 20.9 0.0 2.6 8.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KEZ41250.1 - 0.0004 19.8 0.6 0.66 9.3 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KEZ41250.1 - 0.00046 20.0 0.3 38 3.9 0.0 5.1 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.6 KEZ41250.1 - 0.00047 19.8 0.8 0.2 11.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KEZ41250.1 - 0.00084 19.7 0.2 0.28 11.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KEZ41250.1 - 0.0009 19.8 0.0 6.8 7.2 0.0 4.7 3 0 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 KEZ41250.1 - 0.0019 17.6 0.0 2.4 7.5 0.0 4.0 4 0 0 4 4 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KEZ41250.1 - 0.0028 17.4 0.3 0.42 10.3 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_24 PF13479.6 KEZ41250.1 - 0.0035 17.1 0.4 15 5.2 0.0 4.3 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 KEZ41250.1 - 0.049 13.5 0.0 10 6.0 0.0 3.5 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 KEZ41250.1 - 0.058 13.3 0.5 6.6 6.6 0.0 3.7 5 0 0 5 5 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KEZ41250.1 - 0.061 13.7 0.1 2.5e+02 2.1 0.0 4.5 4 0 0 4 4 4 0 RNA helicase DUF3087 PF11286.8 KEZ41250.1 - 0.088 12.3 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Mso1_Sec1_bdg PF14475.6 KEZ41250.1 - 0.099 12.3 0.1 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Sec1-binding region of Mso1 DUF4482 PF14818.6 KEZ41250.1 - 0.1 13.5 6.6 58 4.6 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) ER PF01133.17 KEZ41250.1 - 0.14 12.2 0.6 39 4.4 0.0 4.7 5 0 0 5 5 5 0 Enhancer of rudimentary MbeB_N PF04837.12 KEZ41250.1 - 0.18 12.1 2.2 2.9 8.3 0.1 3.5 2 0 0 2 2 2 0 MbeB-like, N-term conserved region ALMT PF11744.8 KEZ41250.1 - 0.69 8.7 3.5 1.8 7.3 3.5 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter CLZ PF16526.5 KEZ41250.1 - 5.2 7.5 15.3 0.091 13.1 1.1 4.7 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 KEZ41250.1 - 6.1 7.2 16.5 27 5.1 0.9 6.9 6 0 0 6 6 4 0 Bacterial protein of unknown function (DUF948) CCDC158 PF15921.5 KEZ41251.1 - 0.0022 15.9 0.7 0.0031 15.4 0.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 FAR1 PF03101.15 KEZ41251.1 - 0.0041 17.8 0.0 0.012 16.3 0.0 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain Golgin_A5 PF09787.9 KEZ41251.1 - 0.01 15.3 2.1 0.019 14.5 2.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nnf1 PF03980.14 KEZ41251.1 - 3.3 8.1 7.8 0.53 10.7 2.0 2.7 3 0 0 3 3 3 0 Nnf1 NOA36 PF06524.12 KEZ41252.1 - 0.02 14.2 1.2 0.031 13.6 1.2 1.2 1 0 0 1 1 1 0 NOA36 protein Opi1 PF08618.10 KEZ41252.1 - 0.064 12.5 4.2 0.12 11.6 4.2 1.3 1 0 0 1 1 1 0 Transcription factor Opi1 DUF2511 PF10709.9 KEZ41252.1 - 0.066 13.5 0.0 6 7.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2511) Acetyltransf_1 PF00583.25 KEZ41253.1 - 0.00029 21.0 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TAF PF02969.17 KEZ41254.1 - 0.0021 18.2 0.1 0.0028 17.8 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 KEZ41254.1 - 0.033 14.3 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Svf1_C PF17187.4 KEZ41255.1 - 2.6e-60 203.0 0.0 7e-60 201.6 0.0 1.7 3 0 0 3 3 3 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KEZ41255.1 - 2.7e-54 183.6 0.1 3.7e-54 183.2 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain GATA PF00320.27 KEZ41256.1 - 3.9e-14 52.0 2.4 6.8e-14 51.2 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Macoilin PF09726.9 KEZ41256.1 - 0.0019 16.9 1.6 0.0022 16.6 1.6 1.1 1 0 0 1 1 1 1 Macoilin family APG6_N PF17675.1 KEZ41256.1 - 0.013 16.0 10.9 0.024 15.2 10.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Tektin PF03148.14 KEZ41256.1 - 0.024 13.4 7.3 0.038 12.8 7.3 1.3 1 0 0 1 1 1 0 Tektin family ArfGap PF01412.18 KEZ41256.1 - 0.06 13.4 0.9 0.099 12.7 0.1 1.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF4164 PF13747.6 KEZ41256.1 - 0.062 13.6 9.3 0.11 12.8 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Abi_C PF14355.6 KEZ41256.1 - 0.07 13.2 1.7 0.12 12.4 1.7 1.4 1 0 0 1 1 1 0 Abortive infection C-terminus Taxilin PF09728.9 KEZ41256.1 - 0.14 11.3 7.9 0.17 11.0 7.1 1.5 1 1 0 1 1 1 0 Myosin-like coiled-coil protein KxDL PF10241.9 KEZ41256.1 - 0.15 12.4 3.3 0.27 11.5 3.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein FUSC PF04632.12 KEZ41256.1 - 0.18 10.3 5.0 0.23 10.0 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 KEZ41256.1 - 0.57 9.2 8.0 0.95 8.5 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KEZ41256.1 - 1.3 7.9 8.1 1.8 7.4 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 KEZ41256.1 - 1.3 9.2 20.7 0.022 15.0 13.4 1.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FemAB PF02388.16 KEZ41256.1 - 2.6 6.9 3.9 3.4 6.5 3.9 1.1 1 0 0 1 1 1 0 FemAB family CHD5 PF04420.14 KEZ41256.1 - 3.1 7.7 3.7 13 5.7 3.7 1.8 1 1 0 1 1 1 0 CHD5-like protein ADIP PF11559.8 KEZ41256.1 - 4.4 7.4 11.9 7.7 6.6 10.8 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CLZ PF16526.5 KEZ41256.1 - 7.7 7.0 11.1 3.6 8.0 8.4 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels K_channel_TID PF07941.11 KEZ41256.1 - 8.5 6.9 12.1 14 6.2 2.9 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Mit_KHE1 PF10173.9 KEZ41257.1 - 3.1e-61 206.8 0.6 4.7e-61 206.2 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related eIF3g PF12353.8 KEZ41258.1 - 0.088 13.2 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Cullin PF00888.22 KEZ41259.1 - 1e-196 655.3 10.4 1.4e-196 654.9 10.4 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEZ41259.1 - 6.2e-25 87.0 4.7 6.2e-25 87.0 4.7 3.4 5 0 0 5 5 5 1 Cullin protein neddylation domain Rrf2 PF02082.20 KEZ41259.1 - 0.022 15.1 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Avl9 PF09794.9 KEZ41260.1 - 2.7e-145 483.8 0.0 3.3e-145 483.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KEZ41260.1 - 6.7e-08 32.5 0.1 3.3e-06 26.9 0.1 2.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KEZ41260.1 - 8.3e-07 29.0 0.1 0.00025 21.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF4457 PF14652.6 KEZ41260.1 - 0.039 13.2 0.1 0.064 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) Pkinase PF00069.25 KEZ41261.1 - 3.3e-67 226.7 0.0 4e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41261.1 - 2.7e-32 112.1 0.0 3.2e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEZ41261.1 - 5.8e-06 25.5 0.1 8e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEZ41261.1 - 3e-05 23.5 0.1 9.2e-05 21.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ41261.1 - 0.00056 19.9 0.1 0.0015 18.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEZ41261.1 - 0.0017 17.7 0.0 0.043 13.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 KEZ41261.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 KEZ41261.1 - 0.026 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Phosphorylase PF00343.20 KEZ41262.1 - 0 1042.5 0.0 0 1042.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 KEZ41263.1 - 2.3e-91 306.6 0.9 1.7e-59 201.8 0.3 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KEZ41263.1 - 8.9e-13 48.1 0.5 2.3e-07 30.5 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Rad17 PF03215.15 KEZ41263.1 - 0.0059 16.6 0.2 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain Roc PF08477.13 KEZ41263.1 - 0.029 14.6 0.5 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KEZ41263.1 - 0.047 13.1 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 KEZ41263.1 - 0.062 12.6 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KEZ41263.1 - 0.084 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SH3_9 PF14604.6 KEZ41264.1 - 3.1e-10 39.8 0.1 1.7e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KEZ41264.1 - 8e-05 22.2 0.7 0.00023 20.8 0.7 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ41264.1 - 0.024 14.2 4.1 0.057 13.0 4.1 1.6 1 0 0 1 1 1 0 SH3 domain Anoctamin PF04547.12 KEZ41265.1 - 2.4e-110 369.5 6.0 2.9e-110 369.2 6.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel RRM_1 PF00076.22 KEZ41266.1 - 1.4e-21 76.1 0.0 2.3e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 KEZ41267.1 - 1.1e-60 205.0 0.0 1.6e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEZ41267.1 - 7.2e-35 120.3 0.3 1.8e-34 119.0 0.3 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEZ41267.1 - 3.2e-20 72.8 0.0 1.1e-19 71.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KEZ41267.1 - 0.05 13.8 0.1 0.15 12.3 0.0 2.0 2 1 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 KEZ41268.1 - 2.5e-218 726.5 0.0 4.9e-218 725.6 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KEZ41268.1 - 7.2e-93 311.1 3.3 1.9e-92 309.7 0.2 3.2 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KEZ41268.1 - 2.6e-42 144.6 4.9 7e-17 60.4 0.1 3.7 1 1 2 3 3 3 3 Cell morphogenesis central region HEAT PF02985.22 KEZ41268.1 - 0.032 14.5 2.6 1.1 9.6 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 KEZ41268.1 - 0.065 13.6 0.8 16 6.0 0.0 4.4 5 0 0 5 5 5 0 HEAT repeats Cnd1 PF12717.7 KEZ41268.1 - 0.36 10.8 2.2 12 5.9 0.1 3.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DIM1 PF02966.16 KEZ41269.1 - 1.2e-66 222.5 0.0 1.4e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 KEZ41269.1 - 0.1 13.0 0.2 0.18 12.1 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like Sec62 PF03839.16 KEZ41270.1 - 1.7e-72 243.4 2.6 1.7e-72 243.4 2.6 1.5 2 0 0 2 2 2 1 Translocation protein Sec62 DSBA PF01323.20 KEZ41270.1 - 0.02 14.7 0.7 0.051 13.4 0.7 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Corona_M PF01635.18 KEZ41270.1 - 7 5.9 7.1 11 5.3 7.1 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein PLDc_2 PF13091.6 KEZ41271.1 - 4.9e-15 55.6 0.0 7.5e-07 29.1 0.1 3.3 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KEZ41271.1 - 3.1e-11 43.0 0.1 0.00018 21.5 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Spt20 PF12090.8 KEZ41271.1 - 0.16 11.5 2.9 0.26 10.9 2.9 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KEZ41271.1 - 0.43 10.7 6.1 0.88 9.7 6.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Thioredoxin PF00085.20 KEZ41272.1 - 1.6e-39 134.1 1.2 2.8e-24 85.1 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KEZ41272.1 - 3.7e-13 49.8 0.0 0.00029 20.8 0.0 3.7 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEZ41272.1 - 6.5e-07 29.6 0.7 0.016 15.5 0.0 5.1 4 2 0 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KEZ41272.1 - 3.5e-06 27.4 7.2 0.016 15.6 0.1 4.2 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KEZ41272.1 - 0.00027 20.4 1.6 0.81 9.0 0.4 3.5 4 0 0 4 4 4 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KEZ41272.1 - 0.00044 19.4 0.0 0.00094 18.3 0.0 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.6 KEZ41272.1 - 0.083 13.1 0.3 0.56 10.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like TrbC_Ftype PF09673.10 KEZ41272.1 - 0.14 12.2 0.8 0.57 10.3 0.0 2.4 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein Tyr-DNA_phospho PF06087.12 KEZ41273.1 - 7.4e-156 519.3 0.0 8.5e-156 519.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KEZ41273.1 - 0.00015 21.6 0.4 0.041 13.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KEZ41273.1 - 0.071 13.3 0.3 3.1 8.1 0.4 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif ACBP PF00887.19 KEZ41274.1 - 9.1e-23 80.3 0.9 1.1e-22 80.1 0.9 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.14 KEZ41275.1 - 3.6e-41 141.3 0.8 4.6e-41 141.0 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ41275.1 - 1.7e-09 38.1 0.2 1e-07 32.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ41275.1 - 8.9e-05 21.9 0.2 0.00014 21.2 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ41275.1 - 0.00015 21.7 0.2 1.8 8.5 0.0 3.5 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ41275.1 - 0.015 14.4 0.1 1 8.3 0.0 2.8 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KEZ41275.1 - 0.028 13.6 0.1 8.5 5.5 0.0 3.1 3 0 0 3 3 3 0 FAD binding domain K_oxygenase PF13434.6 KEZ41275.1 - 0.041 13.0 0.5 2.8 7.0 0.5 3.0 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEZ41275.1 - 0.11 11.7 0.7 1.2 8.3 0.3 2.6 2 1 1 3 3 3 0 Thi4 family End3 PF12761.7 KEZ41276.1 - 1.9e-78 263.2 5.5 2.5e-78 262.8 5.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KEZ41276.1 - 2.3e-49 165.7 0.0 7.3e-48 160.8 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KEZ41276.1 - 3.1e-07 29.5 0.2 6.8e-07 28.4 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KEZ41276.1 - 8.4e-06 26.1 0.0 3.6e-05 24.1 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KEZ41276.1 - 0.00089 19.0 0.3 0.0028 17.5 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 KEZ41276.1 - 0.0018 18.1 0.1 0.0034 17.2 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair LPP PF04728.13 KEZ41276.1 - 0.019 15.4 1.4 6.3 7.3 0.3 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper EF-hand_5 PF13202.6 KEZ41276.1 - 0.024 14.1 0.2 0.057 12.9 0.2 1.7 1 0 0 1 1 1 0 EF hand LRS4 PF10422.9 KEZ41276.1 - 0.034 13.7 2.9 0.051 13.2 2.9 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF2408 PF10303.9 KEZ41276.1 - 0.044 14.4 0.6 0.044 14.4 0.6 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) CSN5_C PF18323.1 KEZ41276.1 - 0.046 14.6 2.6 0.29 12.1 2.6 2.5 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Med28 PF11594.8 KEZ41276.1 - 0.05 13.7 1.0 0.12 12.5 1.0 1.6 1 1 0 1 1 1 0 Mediator complex subunit 28 Vps52 PF04129.12 KEZ41276.1 - 0.072 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family SKA1 PF07160.12 KEZ41276.1 - 0.085 12.7 2.4 0.27 11.0 0.1 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 KxDL PF10241.9 KEZ41276.1 - 0.11 12.8 1.3 0.7 10.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.12 KEZ41276.1 - 0.16 12.0 1.5 0.32 11.0 1.5 1.5 1 0 0 1 1 1 0 Laminin Domain II FlxA PF14282.6 KEZ41276.1 - 0.31 11.1 5.3 1.9 8.5 1.6 2.5 1 1 1 2 2 2 0 FlxA-like protein COG2 PF06148.11 KEZ41276.1 - 0.36 10.9 2.9 2.8 8.1 0.2 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MscS_porin PF12795.7 KEZ41276.1 - 0.4 10.2 8.3 3.7 7.0 1.6 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF641 PF04859.12 KEZ41276.1 - 0.45 10.9 2.9 0.8 10.0 0.7 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 KEZ41276.1 - 0.6 9.4 7.1 1.3 8.3 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 KEZ41276.1 - 1.8 8.7 3.8 6.7 6.9 3.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 KEZ41276.1 - 2.4 8.2 8.1 6.1 6.9 8.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KEZ41276.1 - 3.3 8.4 7.7 4.3 8.0 0.3 3.3 3 0 0 3 3 3 0 SlyX FlaC_arch PF05377.11 KEZ41276.1 - 3.4 8.1 5.4 44 4.6 0.6 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 KEZ41276.1 - 4.1 7.5 11.0 5.3 7.1 0.3 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FAS_I_H PF18314.1 KEZ41277.1 - 1.6e-78 263.0 0.6 3.1e-78 262.1 0.1 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KEZ41277.1 - 7.4e-76 254.0 0.1 2.5e-75 252.3 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KEZ41277.1 - 5.4e-21 75.3 1.1 7.4e-21 74.9 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KEZ41277.1 - 3.5e-18 65.8 0.2 1.3e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KEZ41277.1 - 1.6e-11 44.3 0.0 4.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KEZ41277.1 - 8.7e-06 25.3 0.0 2.4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ41277.1 - 0.0019 18.1 0.0 0.0085 16.0 0.0 2.2 2 0 0 2 2 2 1 KR domain PnpCD_PnpD_N PF18191.1 KEZ41277.1 - 0.09 12.4 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal DUF1729 PF08354.10 KEZ41278.1 - 9.1e-157 521.5 0.0 1.4e-156 520.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KEZ41278.1 - 6.2e-89 298.6 0.0 2.1e-86 290.3 0.0 3.0 3 0 0 3 3 3 2 Acyl transferase domain FAS_meander PF17951.1 KEZ41278.1 - 7.4e-54 181.5 0.0 1.9e-53 180.2 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 KEZ41278.1 - 4.5e-39 133.4 0.0 1.8e-38 131.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KEZ41278.1 - 1.6e-37 127.8 0.0 3.7e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KEZ41278.1 - 5.5e-35 121.2 0.0 1.2e-34 120.2 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 KEZ41278.1 - 3.3e-22 79.1 0.1 1.1e-21 77.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.15 KEZ41278.1 - 0.0042 16.5 0.4 0.069 12.5 0.4 2.7 1 1 0 1 1 1 1 Nitronate monooxygenase Amidohydro_1 PF01979.20 KEZ41279.1 - 3.6e-69 233.7 0.0 5.4e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ41279.1 - 4.4e-07 29.7 0.5 2.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family PPR_long PF17177.4 KEZ41279.1 - 0.0004 19.8 0.0 0.0021 17.4 0.0 2.0 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KEZ41279.1 - 0.00058 20.0 0.0 26 5.1 0.0 4.9 5 0 0 5 5 5 1 PPR repeat family PPR_3 PF13812.6 KEZ41279.1 - 0.00085 19.4 0.0 0.4 10.8 0.0 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 KEZ41279.1 - 0.038 14.2 0.4 57 4.3 0.0 4.6 4 0 0 4 4 4 0 PPR repeat Zn_clus PF00172.18 KEZ41280.1 - 1.2e-05 25.3 10.3 2.2e-05 24.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.16 KEZ41281.1 - 4.1e-46 157.3 0.0 9.8e-46 156.0 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KEZ41281.1 - 6e-35 121.0 0.0 8.6e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KEZ41281.1 - 2.9e-27 95.2 1.0 1.1e-26 93.3 1.0 2.0 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KEZ41281.1 - 1.3e-11 44.0 0.1 2.5e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain Ferrochelatase PF00762.19 KEZ41282.1 - 8.2e-100 333.9 0.0 1.2e-99 333.4 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase AAA PF00004.29 KEZ41282.1 - 1.6e-11 44.7 0.0 4.5e-11 43.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ41282.1 - 3e-06 27.6 0.0 7.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEZ41282.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KEZ41282.1 - 0.00016 21.7 0.0 0.00059 19.8 0.0 1.9 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KEZ41282.1 - 0.00065 20.1 0.0 0.005 17.2 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KEZ41282.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEZ41282.1 - 0.0015 18.5 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEZ41282.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KEZ41282.1 - 0.0037 17.0 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KEZ41282.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF4648 PF15505.6 KEZ41282.1 - 0.038 14.9 1.3 0.9 10.5 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4648) NTPase_1 PF03266.15 KEZ41282.1 - 0.068 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 KEZ41282.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ41282.1 - 0.17 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ41282.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 KEZ41282.1 - 0.21 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 KEZ41283.1 - 7.5e-34 117.2 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KEZ41283.1 - 1.4e-24 86.8 0.0 2.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KEZ41283.1 - 1.2e-19 70.3 0.0 2.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 KEZ41283.1 - 1.9e-05 24.6 0.1 8.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KEZ41283.1 - 7e-05 22.9 0.5 0.0015 18.6 0.5 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 KEZ41283.1 - 0.00028 20.9 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 KEZ41283.1 - 0.0026 17.2 0.1 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KEZ41283.1 - 0.0028 18.0 0.1 0.0049 17.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 KEZ41283.1 - 0.0043 16.5 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_24 PF13479.6 KEZ41283.1 - 0.0095 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KEZ41283.1 - 0.014 15.0 0.2 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 KEZ41283.1 - 0.066 12.2 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KEZ41283.1 - 0.076 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ41283.1 - 0.16 12.4 0.1 0.4 11.1 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEZ41283.1 - 0.17 12.1 0.4 0.46 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 KEZ41283.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FeoB_N PF02421.18 KEZ41283.1 - 0.19 11.3 0.2 0.85 9.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Pmp3 PF01679.17 KEZ41284.1 - 4.7e-20 71.5 8.5 6.2e-20 71.1 8.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.10 KEZ41285.1 - 6.1e-63 213.4 0.0 1e-62 212.7 0.0 1.2 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 K_channel_TID PF07941.11 KEZ41285.1 - 0.37 11.3 4.3 44 4.6 5.0 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.13 KEZ41285.1 - 0.74 9.7 5.7 1.1 9.1 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IPK PF03770.16 KEZ41286.1 - 1.3e-51 175.3 0.0 1.8e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase BetaGal_dom2 PF10435.9 KEZ41286.1 - 0.049 13.4 0.1 0.096 12.5 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 OB_NTP_bind PF07717.16 KEZ41287.1 - 2.6e-22 78.9 0.0 5.2e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEZ41287.1 - 3.4e-21 75.5 0.1 3.4e-21 75.5 0.1 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEZ41287.1 - 1.4e-13 51.1 0.0 3.7e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Methyltransf_11 PF08241.12 KEZ41287.1 - 2.3e-13 50.6 0.0 6e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ41287.1 - 3.8e-12 46.3 0.0 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain S1 PF00575.23 KEZ41287.1 - 4.5e-12 46.2 0.4 9.5e-12 45.1 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Methyltransf_25 PF13649.6 KEZ41287.1 - 7.7e-10 39.4 0.0 6.1e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41287.1 - 1.1e-09 38.9 0.0 2.7e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41287.1 - 1.1e-07 31.8 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DEAD PF00270.29 KEZ41287.1 - 1.8e-06 27.9 0.2 3.6e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEZ41287.1 - 3.2e-06 27.5 0.1 8e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEZ41287.1 - 0.00047 19.3 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 KEZ41287.1 - 0.001 18.8 0.2 0.0023 17.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain NNMT_PNMT_TEMT PF01234.17 KEZ41287.1 - 0.0012 18.1 0.1 0.0021 17.3 0.1 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family ABC_tran PF00005.27 KEZ41287.1 - 0.012 16.1 0.5 0.4 11.2 0.2 2.7 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.6 KEZ41287.1 - 0.015 15.3 0.2 0.18 11.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KEZ41287.1 - 0.015 15.6 0.2 0.034 14.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ41287.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Methyltransf_9 PF08003.11 KEZ41287.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AAA_24 PF13479.6 KEZ41287.1 - 0.06 13.1 0.0 5.8 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Transformer PF06495.11 KEZ41287.1 - 0.061 13.4 18.4 0.19 11.8 18.4 1.8 1 0 0 1 1 1 0 Fruit fly transformer protein Microtub_bd PF16796.5 KEZ41287.1 - 0.089 12.7 0.1 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 KEZ41287.1 - 0.097 12.1 0.1 0.31 10.5 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 KEZ41287.1 - 0.2 11.2 0.5 0.48 10.0 0.5 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KEZ41287.1 - 0.23 11.8 1.1 0.68 10.3 0.0 2.3 3 0 0 3 3 2 0 AAA ATPase domain Methyltransf_2 PF00891.18 KEZ41288.1 - 6.5e-22 77.9 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_AraC PF00165.23 KEZ41288.1 - 0.18 11.9 0.0 0.58 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Hydrolase_4 PF12146.8 KEZ41289.1 - 1.1e-07 31.4 0.1 1.2e-06 28.0 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ41289.1 - 3.8e-07 30.9 0.2 5e-07 30.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KEZ41289.1 - 1.1e-06 28.3 0.1 0.01 15.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 KEZ41289.1 - 1e-05 24.4 0.0 0.0014 17.4 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KEZ41289.1 - 2e-05 24.4 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KEZ41289.1 - 0.0093 15.5 0.0 0.096 12.2 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 KEZ41289.1 - 0.012 15.5 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.11 KEZ41289.1 - 0.013 14.4 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Mito_carr PF00153.27 KEZ41290.1 - 9.4e-39 131.3 9.5 1.1e-18 66.9 0.3 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S15 PF02129.18 KEZ41291.1 - 2e-08 34.1 0.0 2.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KEZ41291.1 - 6.3e-08 32.2 0.0 3.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KEZ41291.1 - 1.1e-06 28.4 0.0 4e-06 26.6 0.0 1.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KEZ41291.1 - 1.8e-06 27.6 0.0 1.2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ41291.1 - 3.3e-05 23.7 0.0 6.3e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ41291.1 - 3.3e-05 24.6 0.5 4.2e-05 24.3 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KEZ41291.1 - 5.7e-05 21.9 0.0 0.0094 14.7 0.0 2.9 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 KEZ41291.1 - 0.00047 20.1 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.11 KEZ41291.1 - 0.00088 18.2 0.0 0.0033 16.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 KEZ41291.1 - 0.0027 17.6 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 KEZ41292.1 - 1.7e-09 37.7 0.1 3.1e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ41292.1 - 0.00024 21.0 2.8 0.00025 20.9 0.3 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 KEZ41293.1 - 4.6e-75 252.5 0.0 9.7e-75 251.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ41293.1 - 5.6e-49 166.5 0.0 2.9e-47 160.9 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KEZ41293.1 - 2.3e-44 151.9 0.0 3.9e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEZ41293.1 - 2.8e-42 145.4 0.0 5.6e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEZ41293.1 - 1.2e-30 106.0 0.0 2.7e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KEZ41293.1 - 2.7e-30 105.4 0.0 1.4e-28 99.8 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KEZ41293.1 - 6.5e-20 71.7 0.0 1.8e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41293.1 - 2.5e-15 57.0 0.0 1.3e-14 54.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEZ41293.1 - 4.2e-15 56.2 0.0 1.1e-14 54.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KEZ41293.1 - 1e-13 51.7 0.0 3.1e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KEZ41293.1 - 2e-13 50.4 0.0 4.3e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEZ41293.1 - 1.5e-12 47.4 0.1 7e-12 45.2 0.0 2.3 3 0 0 3 3 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KEZ41293.1 - 1.7e-12 47.5 0.0 4.5e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41293.1 - 2.6e-09 37.1 0.0 6.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ41293.1 - 2.7e-07 30.2 0.0 5.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KEZ41293.1 - 3.6e-06 27.2 0.0 9.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KEZ41293.1 - 4.2e-06 26.4 0.0 0.059 12.8 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ41293.1 - 1e-05 24.7 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family MTS PF05175.14 KEZ41293.1 - 0.00054 19.6 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KEZ41293.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_24 PF13578.6 KEZ41293.1 - 0.0065 17.5 0.1 0.045 14.8 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.23 KEZ41293.1 - 0.0091 15.4 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 KEZ41293.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent RrnaAD PF00398.20 KEZ41293.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MFS_1 PF07690.16 KEZ41294.1 - 2.5e-36 125.3 44.7 2.5e-36 125.3 44.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KEZ41295.1 - 6.9e-15 55.1 5.0 1.6e-11 44.0 0.4 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KEZ41295.1 - 1.8e-06 27.4 0.8 0.00022 20.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ41295.1 - 1.3e-05 24.4 0.7 0.0093 15.0 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KEZ41295.1 - 0.00031 19.7 0.0 0.021 13.7 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 KEZ41295.1 - 0.0015 17.4 0.1 0.46 9.1 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KEZ41295.1 - 0.0035 17.0 0.6 0.85 9.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ41295.1 - 0.014 14.5 0.4 0.023 13.8 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KEZ41295.1 - 0.072 13.1 0.1 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KEZ41295.1 - 0.1 11.9 0.4 0.79 9.0 0.2 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ41295.1 - 0.11 11.8 0.0 11 5.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Git3 PF11710.8 KEZ41296.1 - 3.5e-66 222.8 19.0 5e-66 222.3 15.8 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KEZ41296.1 - 1.9e-21 75.9 0.3 1.9e-21 75.9 0.3 3.2 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KEZ41296.1 - 4.6e-08 32.7 0.5 6.4e-08 32.2 0.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 KEZ41296.1 - 0.0001 21.7 15.3 0.00028 20.2 10.7 2.7 2 1 0 2 2 2 1 Pheromone A receptor DUF4381 PF14316.6 KEZ41296.1 - 0.069 13.4 1.0 0.32 11.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) GATase PF00117.28 KEZ41297.1 - 6e-14 52.2 0.0 8.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KEZ41297.1 - 0.0008 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KEZ41297.1 - 0.014 15.2 0.2 0.12 12.1 0.2 2.3 1 1 0 1 1 1 0 Peptidase C26 DHHA2 PF02833.14 KEZ41298.1 - 6.1e-34 117.2 0.0 1.2e-33 116.4 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KEZ41298.1 - 6.5e-11 42.4 0.1 9.9e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 DHH family DUF3574 PF12098.8 KEZ41298.1 - 0.16 11.8 0.0 0.82 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) RNA_pol PF00940.19 KEZ41299.1 - 5.7e-184 611.7 0.0 9.8e-184 611.0 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KEZ41299.1 - 2.2e-97 326.5 1.8 3.4e-97 325.8 1.1 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal SNF2_N PF00176.23 KEZ41300.1 - 2e-60 204.3 0.0 8.4e-60 202.3 0.0 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ41300.1 - 1.9e-21 76.5 0.0 4.2e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ41300.1 - 8.5e-08 32.4 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEZ41300.1 - 0.0019 17.4 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KEZ41300.1 - 0.0049 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KEZ41300.1 - 0.039 13.6 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 SWI2/SNF2 ATPase DUF4674 PF15719.5 KEZ41300.1 - 5 7.1 0.0 5 7.1 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4674) Phosphodiest PF01663.22 KEZ41301.1 - 1.5e-93 314.2 0.3 2.6e-93 313.5 0.3 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KEZ41301.1 - 0.00079 18.9 0.2 0.0014 18.0 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KEZ41301.1 - 0.0037 16.7 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.12 KEZ41301.1 - 0.0037 17.4 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 PglZ domain Orf78 PF06024.12 KEZ41301.1 - 0.059 13.7 0.7 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) PBP_N PF17093.5 KEZ41301.1 - 0.061 13.6 4.8 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus DUF5383 PF17355.2 KEZ41301.1 - 0.2 12.0 0.9 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5383) U1snRNP70_N PF12220.8 KEZ41301.1 - 3.6 8.3 11.1 1.9 9.2 3.0 2.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ank_5 PF13857.6 KEZ41303.1 - 4.3e-15 55.6 1.4 0.0002 21.6 0.0 5.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ41303.1 - 3.4e-13 48.5 1.9 0.043 14.4 0.1 7.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_2 PF12796.7 KEZ41303.1 - 2.1e-11 44.3 0.0 1.4e-05 25.5 0.1 4.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ41303.1 - 5.7e-11 42.7 0.2 0.0029 18.2 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KEZ41303.1 - 2.8e-05 24.3 5.5 0.29 11.7 0.1 5.7 8 0 0 8 8 6 2 Ankyrin repeat Helo_like_N PF17111.5 KEZ41303.1 - 0.0001 21.8 0.4 0.0002 20.8 0.4 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KEZ41303.1 - 0.0097 16.2 0.1 0.034 14.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain SesA PF17107.5 KEZ41303.1 - 0.015 15.4 0.5 0.035 14.3 0.5 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PEPcase PF00311.17 KEZ41303.1 - 0.057 11.5 0.1 0.076 11.1 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF5578 PF17741.1 KEZ41303.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5578) DUF1843 PF08898.10 KEZ41303.1 - 0.26 11.8 2.4 28 5.3 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) SNF PF00209.18 KEZ41304.1 - 2e-81 274.3 33.6 3.1e-80 270.3 33.6 2.1 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4605 PF15378.6 KEZ41304.1 - 0.054 13.4 0.6 0.054 13.4 0.6 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4605) DUF3810 PF12725.7 KEZ41304.1 - 0.068 12.5 1.7 0.22 10.8 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) adh_short_C2 PF13561.6 KEZ41305.1 - 5.5e-45 153.7 0.1 8e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ41305.1 - 1.5e-36 125.7 0.1 2.2e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ41305.1 - 4.3e-10 39.8 0.2 7.2e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ41305.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEZ41306.1 - 9e-08 32.2 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DUF3385 PF11865.8 KEZ41306.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) DapB_N PF01113.20 KEZ41306.1 - 0.033 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KEZ41306.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SKG6 PF08693.10 KEZ41307.1 - 0.00016 21.0 6.9 0.00027 20.3 6.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sugar_tr PF00083.24 KEZ41308.1 - 4e-122 408.3 20.3 4.6e-122 408.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41308.1 - 2.1e-22 79.5 35.7 9.7e-15 54.3 12.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KEZ41308.1 - 0.014 15.6 1.4 0.014 15.6 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) NAD_synthase PF02540.17 KEZ41309.1 - 1.9e-18 66.5 0.0 3.6e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 KEZ41309.1 - 8e-12 45.0 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase His_Phos_2 PF00328.22 KEZ41310.1 - 1e-12 48.1 2.9 5.1e-11 42.5 0.2 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF3592 PF12158.8 KEZ41310.1 - 0.12 12.4 1.5 1.2 9.2 1.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) Mucin PF01456.17 KEZ41311.1 - 0.0016 18.4 10.9 0.0034 17.4 10.9 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SPX PF03105.19 KEZ41311.1 - 0.053 13.4 0.8 0.056 13.4 0.8 1.2 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KEZ41311.1 - 0.067 12.4 4.3 0.074 12.2 4.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SpoIIIAH PF12685.7 KEZ41311.1 - 0.12 12.1 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein OAD_gamma PF04277.13 KEZ41311.1 - 0.15 12.7 1.5 0.39 11.3 1.5 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FAM70 PF14967.6 KEZ41311.1 - 0.6 9.5 5.8 0.13 11.7 1.5 1.8 2 0 0 2 2 2 0 FAM70 protein Pkinase PF00069.25 KEZ41312.1 - 2.4e-26 92.7 0.0 3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41312.1 - 3.8e-14 52.6 0.0 5.2e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ41312.1 - 4.1e-09 35.7 0.0 5.8e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEZ41312.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KEZ41312.1 - 0.054 12.5 0.1 0.081 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro_61 PF03443.14 KEZ41313.1 - 1.9e-22 80.2 0.1 3.1e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_3 PF13606.6 KEZ41313.1 - 3.6e-10 39.2 0.5 6.2e-05 23.1 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KEZ41313.1 - 5.9e-10 39.6 0.0 1.2e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ41313.1 - 5.5e-09 36.4 0.0 3.1e-07 30.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEZ41313.1 - 1e-08 35.2 0.2 0.00015 22.0 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KEZ41313.1 - 2.1e-07 31.1 0.0 0.00065 20.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Prok-E2_C PF14459.6 KEZ41313.1 - 0.035 14.3 0.1 0.084 13.0 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family C p450 PF00067.22 KEZ41314.1 - 6e-19 68.1 0.0 6.5e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 KEZ41315.1 - 4.7e-68 225.8 0.5 2.8e-11 43.8 0.0 8.3 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ41315.1 - 9.2e-43 144.1 8.1 9.3e-06 26.1 0.0 14.1 6 5 7 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ41315.1 - 4.7e-41 134.1 16.8 0.021 15.3 0.0 17.7 18 0 0 18 18 18 9 Ankyrin repeat Ank PF00023.30 KEZ41315.1 - 4.8e-34 115.3 25.0 0.015 15.7 0.0 16.8 16 2 0 16 16 16 9 Ankyrin repeat Ank_5 PF13857.6 KEZ41315.1 - 5.2e-33 112.7 10.9 3.8e-05 23.9 0.0 10.7 7 3 4 11 11 11 10 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ41315.1 - 1.2e-05 25.3 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ41315.1 - 0.00013 22.4 0.6 0.00062 20.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ41315.1 - 0.00015 22.0 0.0 0.00073 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Helo_like_N PF17111.5 KEZ41315.1 - 0.00025 20.5 0.2 0.0006 19.2 0.2 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins VGCC_beta4Aa_N PF12052.8 KEZ41315.1 - 0.011 15.9 0.1 0.029 14.5 0.1 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal SesA PF17107.5 KEZ41315.1 - 0.015 15.5 0.1 0.092 12.9 0.1 2.3 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases KAP_NTPase PF07693.14 KEZ41315.1 - 0.081 12.1 0.2 1.1 8.4 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.6 KEZ41315.1 - 0.1 12.3 0.0 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 KEZ41315.1 - 0.17 11.9 0.8 13 5.9 0.0 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus 3Beta_HSD PF01073.19 KEZ41316.1 - 1.5e-52 178.4 0.0 1.9e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEZ41316.1 - 2e-28 99.5 0.2 3e-28 98.9 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ41316.1 - 2.4e-15 56.8 0.2 1.2e-12 47.9 0.2 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ41316.1 - 1.3e-10 40.9 0.1 5e-08 32.4 0.1 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KEZ41316.1 - 2.2e-06 27.0 0.5 8e-06 25.2 0.5 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KEZ41316.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KEZ41316.1 - 2.6e-05 23.5 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KEZ41316.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family KR PF08659.10 KEZ41316.1 - 0.034 14.1 0.3 1.1 9.1 0.3 2.8 1 1 0 1 1 1 0 KR domain p450 PF00067.22 KEZ41317.1 - 1.6e-34 119.5 0.0 2.8e-34 118.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_49N PF17433.2 KEZ41317.1 - 0.12 12.0 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain Pkinase PF00069.25 KEZ41318.1 - 3.6e-37 128.2 0.0 5.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41318.1 - 5.4e-20 71.8 0.0 8.7e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ41318.1 - 0.02 14.2 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like FHA PF00498.26 KEZ41318.1 - 0.034 14.5 0.0 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 FHA domain Pkinase_fungal PF17667.1 KEZ41318.1 - 0.068 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Protoglobin PF11563.8 KEZ41319.1 - 1.2e-54 184.5 0.2 1.5e-54 184.2 0.2 1.1 1 0 0 1 1 1 1 Protoglobin SET PF00856.28 KEZ41320.1 - 7.5e-12 46.0 0.1 2.4e-11 44.3 0.1 1.8 1 1 0 1 1 1 1 SET domain OTT_1508_deam PF14441.6 KEZ41321.1 - 3.7e-19 68.5 0.3 6.8e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-C2H2_11 PF16622.5 KEZ41322.1 - 0.029 14.1 1.6 0.076 12.8 0.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KEZ41322.1 - 0.031 15.1 1.3 0.49 11.4 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ41322.1 - 0.098 13.2 1.4 2.7 8.6 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Exo_endo_phos PF03372.23 KEZ41324.1 - 0.00029 20.4 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0561 PF10573.9 KEZ41324.1 - 0.06 13.5 0.3 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Pkinase PF00069.25 KEZ41325.1 - 8.6e-67 225.3 0.0 1e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41325.1 - 6.4e-31 107.6 0.0 8.4e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ41325.1 - 4e-05 23.1 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ41325.1 - 0.0012 18.8 0.1 0.085 12.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEZ41325.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KEZ41325.1 - 0.054 12.3 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KEZ41325.1 - 0.14 11.1 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RabGAP-TBC PF00566.18 KEZ41326.1 - 1.9e-46 158.4 0.0 3e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KEZ41326.1 - 7.3e-06 25.5 1.4 0.0021 17.9 0.6 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KEZ41326.1 - 0.00054 19.3 3.3 0.12 12.0 1.9 3.4 3 0 0 3 3 3 2 EF hand GRAM PF02893.20 KEZ41326.1 - 0.0027 17.6 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 KEZ41326.1 - 0.008 16.6 5.5 0.44 11.0 0.2 3.4 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 KEZ41326.1 - 0.078 12.5 1.3 0.26 10.9 1.3 2.0 1 0 0 1 1 1 0 EF hand CNH PF00780.22 KEZ41327.1 - 1.7e-65 221.4 0.0 3e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KEZ41327.1 - 1.1e-32 113.8 0.8 2.1e-32 112.8 0.8 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KEZ41327.1 - 1.7e-10 41.1 0.0 1.1e-09 38.5 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KEZ41327.1 - 0.00047 20.6 0.0 0.026 15.0 0.0 3.1 3 0 0 3 3 3 1 PH domain PH_16 PF17838.1 KEZ41327.1 - 0.0012 18.7 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 PH domain Sod_Cu PF00080.20 KEZ41328.1 - 3e-47 160.4 4.6 3.4e-47 160.2 4.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 KEZ41329.1 - 3.3e-95 318.7 3.0 3.8e-95 318.5 3.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pet191_N PF10203.9 KEZ41330.1 - 1.1e-26 92.8 2.7 1.5e-26 92.5 2.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KEZ41330.1 - 0.065 13.1 0.3 0.09 12.7 0.3 1.2 1 0 0 1 1 1 0 COBRA-like protein Clusterin PF01093.17 KEZ41330.1 - 0.26 10.3 1.6 0.33 9.9 1.6 1.1 1 0 0 1 1 1 0 Clusterin CX9C PF16860.5 KEZ41330.1 - 3.4 7.7 8.8 0.7 9.9 0.9 2.8 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NFACT-C PF11923.8 KEZ41331.1 - 2.3e-38 130.3 0.1 2.3e-38 130.3 0.1 3.2 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 KEZ41331.1 - 1.2e-35 123.1 0.4 1.2e-35 123.1 0.4 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KEZ41331.1 - 6.1e-29 100.9 0.0 1.3e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Methyltransf_2 PF00891.18 KEZ41332.1 - 5.7e-25 87.9 0.0 8.6e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 KEZ41332.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.22 KEZ41333.1 - 7.9e-42 143.6 0.0 1e-41 143.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 A_deamin PF02137.18 KEZ41334.1 - 2.7e-30 105.9 0.0 3.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NAC PF01849.18 KEZ41335.1 - 1e-23 83.0 0.4 5.6e-23 80.7 0.2 2.0 2 0 0 2 2 2 1 NAC domain LEM PF03020.15 KEZ41335.1 - 0.031 13.9 0.1 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 LEM domain CBP4 PF07960.11 KEZ41336.1 - 5.2e-28 97.5 1.9 6e-28 97.3 1.9 1.0 1 0 0 1 1 1 1 CBP4 Topoisom_I_N PF02919.15 KEZ41336.1 - 0.048 13.1 1.4 0.06 12.8 1.4 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Borrelia_P13 PF05628.12 KEZ41336.1 - 0.17 11.9 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Borrelia membrane protein P13 Elongin_A PF06881.11 KEZ41336.1 - 0.32 11.5 6.7 0.41 11.2 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Sel1 PF08238.12 KEZ41337.1 - 1.1e-47 159.3 25.9 2.5e-09 37.5 0.1 7.9 7 0 0 7 7 7 7 Sel1 repeat DUF997 PF06196.12 KEZ41338.1 - 0.12 12.4 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) EGF_2 PF07974.13 KEZ41338.1 - 9.7 6.7 10.4 18 5.8 10.4 1.5 1 0 0 1 1 1 0 EGF-like domain fn3_2 PF16893.5 KEZ41339.1 - 1.7e-38 130.7 0.0 2.7e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KEZ41339.1 - 1.5e-23 82.5 0.8 2.5e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KEZ41339.1 - 1.2e-12 47.6 0.0 2.3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KEZ41339.1 - 4.6e-11 42.9 0.0 7.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KEZ41339.1 - 6.4e-06 26.5 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 KEZ41339.1 - 4.4e-05 23.7 0.0 0.00013 22.3 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Tub_N PF16322.5 KEZ41339.1 - 0.0054 17.2 8.0 0.0075 16.7 8.0 1.1 1 0 0 1 1 1 1 Tubby N-terminal DUF3006 PF11213.8 KEZ41339.1 - 0.0074 16.5 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) EAF PF09816.9 KEZ41340.1 - 1.9e-22 79.5 0.0 4e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CDC27 PF09507.10 KEZ41340.1 - 2.7 7.3 26.0 3.3 7.0 25.4 1.4 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Dicty_REP PF05086.12 KEZ41340.1 - 5.3 4.9 5.2 9.2 4.1 5.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NT-C2 PF10358.9 KEZ41341.1 - 7.6e-24 84.1 0.0 7.7e-20 71.1 0.0 2.1 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins HSP70 PF00012.20 KEZ41342.1 - 7.9e-77 258.8 3.8 1.1e-76 258.4 3.8 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ41342.1 - 7.5e-06 25.0 0.1 1.6e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KEZ41342.1 - 0.0056 15.8 0.2 4.7 6.1 0.0 2.9 3 0 0 3 3 3 2 Type IV pilus assembly protein PilM; FAM176 PF14851.6 KEZ41342.1 - 0.096 12.3 1.3 0.23 11.1 1.3 1.6 1 0 0 1 1 1 0 FAM176 family DUF3221 PF11518.8 KEZ41342.1 - 0.12 12.7 0.5 0.33 11.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) DNA_pol_phi PF04931.13 KEZ41342.1 - 3.3 5.7 5.3 5.3 5.0 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 KEZ41342.1 - 5.5 6.2 5.4 8.8 5.6 5.4 1.2 1 0 0 1 1 1 0 NOA36 protein KH_6 PF15985.5 KEZ41343.1 - 4.5e-17 62.1 1.7 5.1e-17 61.9 0.3 1.9 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 KEZ41343.1 - 2.9e-16 59.1 2.2 2.9e-16 59.1 2.2 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain AAA_12 PF13087.6 KEZ41344.1 - 8.5e-23 81.0 0.0 7.8e-22 77.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KEZ41344.1 - 3.1e-10 40.3 0.0 2.2e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KEZ41344.1 - 2.7e-06 27.3 0.0 0.00073 19.3 0.0 2.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KEZ41344.1 - 6.4e-06 25.9 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 KEZ41344.1 - 0.019 14.5 0.1 0.041 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KEZ41344.1 - 0.065 13.5 0.0 0.38 11.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain Usp PF00582.26 KEZ41344.1 - 0.15 12.5 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Universal stress protein family Zn_clus PF00172.18 KEZ41345.1 - 4.6e-08 33.1 12.0 7.7e-08 32.3 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MdcG PF10620.9 KEZ41345.1 - 0.047 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG GST_C_2 PF13410.6 KEZ41345.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Annexin PF00191.20 KEZ41346.1 - 3.2e-18 65.5 1.2 1.4e-05 25.1 0.0 4.4 4 0 0 4 4 4 3 Annexin FAM196 PF15265.6 KEZ41347.1 - 0.011 15.2 31.1 0.017 14.7 31.1 1.4 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.13 KEZ41347.1 - 4.1 7.3 23.5 6.3 6.7 23.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Oxysterol_BP PF01237.18 KEZ41348.1 - 2.1e-134 448.0 0.0 7.3e-134 446.3 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 KEZ41348.1 - 1.7e-15 56.9 0.3 1.5e-07 31.6 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ41348.1 - 3.3e-14 53.1 0.0 1.9e-08 34.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ41348.1 - 4.4e-14 52.8 0.0 2.2e-08 34.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ41348.1 - 1.9e-13 49.3 0.1 0.00031 21.0 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KEZ41348.1 - 2e-12 47.0 0.2 0.00072 19.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 KEZ41348.1 - 5.7e-12 46.1 0.7 1.2e-11 45.0 0.7 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KEZ41348.1 - 3.9e-08 33.5 1.0 1.3e-07 31.8 1.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KEZ41348.1 - 3.1e-05 24.3 2.1 9e-05 22.8 2.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 KEZ41348.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 PH domain 4HBT_3 PF13622.6 KEZ41349.1 - 6.6e-76 255.8 1.2 8.3e-76 255.5 1.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KEZ41349.1 - 1.2e-24 86.6 0.0 1.3e-17 63.9 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase CRA PF06589.11 KEZ41350.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) AMP-binding PF00501.28 KEZ41351.1 - 4.7e-79 266.0 0.0 6.1e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ41351.1 - 1.1e-12 48.7 0.8 4.7e-12 46.7 0.5 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 KEZ41352.1 - 2.4e-23 83.4 0.0 3.5e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp PF00026.23 KEZ41353.1 - 1.7e-50 172.2 0.0 2.2e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ41353.1 - 2.1e-08 34.6 0.2 5.5e-08 33.2 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEZ41353.1 - 0.0017 18.9 2.6 3.4 8.4 0.7 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KEZ41353.1 - 0.055 14.0 0.8 50 4.6 0.0 3.3 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease ATP12 PF07542.11 KEZ41354.1 - 5e-41 139.8 0.4 8.2e-41 139.1 0.4 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Abhydrolase_2 PF02230.16 KEZ41356.1 - 3.9e-60 203.3 0.0 4.8e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KEZ41356.1 - 0.00011 22.9 0.0 0.00013 22.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KEZ41356.1 - 0.017 14.6 0.1 0.92 8.9 0.0 2.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEZ41356.1 - 0.021 14.1 0.1 15 4.8 0.1 3.0 2 1 1 3 3 3 0 Serine aminopeptidase, S33 FSH1 PF03959.13 KEZ41356.1 - 0.025 14.2 0.0 0.079 12.6 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 KEZ41356.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Cutinase PF01083.22 KEZ41356.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 KEZ41356.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KEZ41356.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Fumble PF03630.14 KEZ41357.1 - 2.6e-145 483.7 0.0 3.3e-145 483.4 0.0 1.1 1 0 0 1 1 1 1 Fumble 2OG-FeII_Oxy_3 PF13640.6 KEZ41358.1 - 1.4e-06 29.0 0.0 2.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RdRP PF05183.12 KEZ41359.1 - 3.5e-184 613.7 0.0 4.7e-184 613.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase hnRNP_Q_AcD PF18360.1 KEZ41359.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain FAD-oxidase_C PF02913.19 KEZ41360.1 - 5.1e-65 219.6 0.1 6.9e-65 219.1 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ41360.1 - 3.6e-34 117.5 0.0 7.5e-34 116.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain YfdX PF10938.8 KEZ41360.1 - 0.16 11.9 0.4 8.6 6.3 0.4 2.4 2 0 0 2 2 2 0 YfdX protein Ribosomal_S4e PF00900.20 KEZ41361.1 - 5.9e-36 122.2 0.3 1.3e-35 121.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KEZ41361.1 - 1.9e-24 85.0 0.0 3.7e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KEZ41361.1 - 8.6e-16 57.8 3.3 1.8e-15 56.7 3.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KEZ41361.1 - 1.8e-06 27.5 0.1 3.3e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KEZ41361.1 - 2.2e-05 24.2 0.7 2.2e-05 24.2 0.7 2.9 4 0 0 4 4 4 1 KOW motif Septin PF00735.18 KEZ41363.1 - 5.8e-31 107.8 0.0 5.2e-11 42.4 0.0 3.1 3 0 0 3 3 3 3 Septin G-alpha PF00503.20 KEZ41363.1 - 0.027 13.6 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.6 KEZ41363.1 - 0.032 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KEZ41363.1 - 0.041 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3313 PF11769.8 KEZ41363.1 - 0.066 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) DGF-1_C PF11040.8 KEZ41363.1 - 0.072 13.1 2.2 0.21 11.6 0.2 2.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus AAA_23 PF13476.6 KEZ41363.1 - 0.074 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ41363.1 - 0.082 13.0 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC1 PF03109.16 KEZ41364.1 - 2.7e-17 63.0 0.0 1e-16 61.2 0.0 1.9 1 1 0 1 1 1 1 ABC1 family APH PF01636.23 KEZ41364.1 - 0.004 17.1 0.4 0.025 14.5 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family SUR7 PF06687.12 KEZ41365.1 - 8.7e-21 74.5 14.4 1.2e-20 74.1 14.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5090 PF17009.5 KEZ41365.1 - 0.39 10.7 4.5 0.56 10.1 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) ELFV_dehydrog PF00208.21 KEZ41366.1 - 0.022 14.5 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF4407 PF14362.6 KEZ41366.1 - 0.39 10.0 4.7 0.6 9.4 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Smg4_UPF3 PF03467.15 KEZ41367.1 - 1.5e-36 126.0 0.0 1.5e-36 126.0 0.0 3.4 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 KEZ41367.1 - 1.7e-05 24.5 0.0 6.9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KEZ41368.1 - 6e-32 111.8 0.0 9.8e-31 107.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KEZ41368.1 - 0.036 13.7 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain EF-hand_6 PF13405.6 KEZ41369.1 - 6.1e-08 32.0 0.1 0.016 15.1 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KEZ41369.1 - 2.1e-05 24.9 0.2 2.1e-05 24.9 0.2 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KEZ41369.1 - 0.00012 21.4 0.5 0.0019 17.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 KEZ41369.1 - 0.014 14.8 0.2 0.1 12.2 0.1 2.3 2 0 0 2 2 2 0 EF hand PDGF_N PF04692.13 KEZ41369.1 - 0.11 13.3 0.2 0.11 13.3 0.2 1.9 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region ORC6 PF05460.13 KEZ41370.1 - 1.8e-30 106.4 1.7 1.8e-30 106.4 1.7 1.9 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) LPMO_10 PF03067.15 KEZ41371.1 - 1.1e-08 36.0 0.1 2e-08 35.1 0.1 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Integrin_alpha PF00357.20 KEZ41372.1 - 0.0012 18.6 1.5 1.4 9.0 0.2 2.9 2 0 0 2 2 2 2 Integrin alpha cytoplasmic region SKG6 PF08693.10 KEZ41372.1 - 0.052 13.0 0.5 0.12 11.8 0.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KEZ41372.1 - 0.67 9.9 7.8 0.041 13.8 1.7 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF4238 PF14022.6 KEZ41373.1 - 4.1e-56 190.5 0.2 6.6e-56 189.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) DUF4710 PF15828.5 KEZ41373.1 - 3.3 7.9 9.2 10 6.3 9.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Fungal_trans PF04082.18 KEZ41374.1 - 1.2e-29 103.2 0.0 3.3e-29 101.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41374.1 - 2.6e-09 37.1 7.6 4.3e-09 36.3 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC_CDC26 PF10471.9 KEZ41374.1 - 3.7 8.4 7.0 2.2 9.2 3.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Fungal_trans PF04082.18 KEZ41375.1 - 3.8e-41 140.9 0.0 6.8e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41375.1 - 1.3e-08 34.8 6.4 2.7e-08 33.8 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipin_mid PF16876.5 KEZ41375.1 - 8.7 6.6 8.4 3.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Lipin/Ned1/Smp2 multi-domain protein middle domain zf-RING_2 PF13639.6 KEZ41376.1 - 6.9e-14 51.9 15.9 1.3e-12 47.8 8.0 2.2 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 KEZ41376.1 - 2.4e-10 40.1 8.7 5.7e-08 32.5 4.4 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ41376.1 - 1.2e-09 37.9 6.7 1.2e-09 37.9 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEZ41376.1 - 2.3e-09 36.8 7.8 5e-09 35.7 4.2 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 KEZ41376.1 - 2.5e-07 30.4 14.0 1e-05 25.3 7.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEZ41376.1 - 2e-06 28.0 6.6 2e-06 28.0 6.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEZ41376.1 - 1.6e-05 24.7 10.5 5.4e-05 23.1 4.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEZ41376.1 - 5e-05 23.2 0.6 5e-05 23.2 0.6 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KEZ41376.1 - 5.9e-05 23.0 4.1 0.00061 19.8 1.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KEZ41376.1 - 7.6e-05 22.5 11.4 0.00015 21.6 5.1 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 HypA PF01155.19 KEZ41376.1 - 0.00039 20.4 2.5 0.014 15.4 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 KEZ41376.1 - 0.0012 19.1 4.8 0.0067 16.7 2.3 2.5 2 0 0 2 2 2 1 zinc-ribbon Baculo_RING PF05883.11 KEZ41376.1 - 0.017 15.1 0.3 0.036 14.0 0.3 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 KEZ41376.1 - 0.28 10.9 16.4 0.36 10.5 7.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 KEZ41376.1 - 0.64 10.0 8.5 3.1 7.8 5.7 2.6 2 0 0 2 2 2 0 PHD-finger DZR PF12773.7 KEZ41376.1 - 0.78 9.8 5.6 3.7 7.7 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 KEZ41376.1 - 0.9 9.6 5.6 8.4 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-RING_4 PF14570.6 KEZ41376.1 - 2.2 8.1 13.0 2.6 7.9 4.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KEZ41376.1 - 3.3 7.9 12.4 6.9 6.9 0.7 2.8 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KEZ41376.1 - 3.5 7.8 4.6 3.1 8.0 1.0 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF1272 PF06906.11 KEZ41376.1 - 4.9 7.3 10.6 0.36 10.9 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) RINGv PF12906.7 KEZ41376.1 - 5 7.3 15.5 1.8 8.7 9.3 2.3 2 0 0 2 2 2 0 RING-variant domain Fis1_TPR_C PF14853.6 KEZ41377.1 - 1.9e-25 88.6 0.7 3.2e-25 88.0 0.7 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KEZ41377.1 - 2.9e-17 62.0 0.1 4.6e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KEZ41377.1 - 0.0051 16.8 0.9 0.0087 16.1 0.9 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.11 KEZ41378.1 - 2.4e-37 127.4 2.6 2.4e-36 124.2 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Paralemmin PF03285.15 KEZ41378.1 - 0.029 14.0 2.1 0.045 13.3 2.1 1.2 1 0 0 1 1 1 0 Paralemmin AA_kinase PF00696.28 KEZ41378.1 - 0.088 12.4 0.2 0.099 12.2 0.2 1.3 1 0 0 1 1 1 0 Amino acid kinase family Aconitase PF00330.20 KEZ41379.1 - 0.017 14.1 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Death PF00531.22 KEZ41379.1 - 0.038 14.2 0.7 0.13 12.5 0.2 2.1 3 0 0 3 3 3 0 Death domain DUF4114 PF13448.6 KEZ41379.1 - 0.19 12.6 0.0 0.38 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) E_Pc_C PF06752.12 KEZ41380.1 - 0.0031 17.7 2.2 0.0031 17.7 2.2 1.6 2 0 0 2 2 2 1 Enhancer of Polycomb C-terminus SUIM_assoc PF16619.5 KEZ41380.1 - 0.098 12.7 7.5 0.075 13.1 5.1 2.0 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 KEZ41380.1 - 0.79 9.3 8.5 1.4 8.5 8.5 1.3 1 0 0 1 1 1 0 Spt20 family DcpS PF05652.12 KEZ41381.1 - 2.4e-35 121.5 0.0 4.3e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KEZ41381.1 - 2.4e-33 115.0 0.1 3.7e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GILT PF03227.16 KEZ41382.1 - 5.6e-18 65.1 0.3 8e-18 64.6 0.3 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_2 PF03727.16 KEZ41383.1 - 2.2e-42 145.2 0.0 2.9e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEZ41383.1 - 7.8e-07 29.2 0.1 0.015 15.2 0.0 2.2 1 1 1 2 2 2 2 Hexokinase Myb_Cef PF11831.8 KEZ41384.1 - 2.1e-52 178.1 7.3 2.1e-52 178.1 7.3 3.2 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KEZ41384.1 - 2.5e-23 82.0 6.3 6.1e-11 42.3 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEZ41384.1 - 1.2e-21 76.7 8.0 1.6e-14 53.9 2.7 3.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2738 PF10927.8 KEZ41384.1 - 0.0054 15.8 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2738) Rap1_C PF11626.8 KEZ41384.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.2 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 KEZ41385.1 - 1.2e-29 103.3 15.4 8.7e-22 77.5 5.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ41385.1 - 2.4e-11 43.2 0.2 4.2e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 KEZ41385.1 - 0.0035 15.7 0.5 0.036 12.3 0.4 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF5326 PF17260.2 KEZ41385.1 - 0.067 13.3 0.2 0.067 13.3 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5326) DUF5368 PF17336.2 KEZ41385.1 - 0.43 10.8 3.2 1.6 9.0 1.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5368) HIT PF01230.23 KEZ41386.1 - 8e-19 68.2 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEZ41386.1 - 0.013 16.0 0.0 0.031 14.8 0.0 1.6 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding UCR_Fe-S_N PF10399.9 KEZ41387.1 - 0.032 13.6 2.7 0.085 12.2 1.6 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ion_trans PF00520.31 KEZ41388.1 - 3.1e-07 29.9 29.0 6.6e-07 28.8 29.0 1.5 1 0 0 1 1 1 1 Ion transport protein CPSase_L_D2 PF02786.17 KEZ41389.1 - 6e-115 382.1 1.1 1e-84 283.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.21 KEZ41389.1 - 4.4e-46 156.6 0.0 1.2e-45 155.2 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.22 KEZ41389.1 - 1.4e-44 151.0 0.0 3.2e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KEZ41389.1 - 8.7e-43 146.3 0.0 3e-42 144.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 KEZ41389.1 - 7.9e-40 136.0 0.2 1.9e-39 134.7 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KEZ41389.1 - 1.1e-28 100.3 0.0 2.6e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KEZ41389.1 - 1.3e-22 79.8 0.0 5.5e-22 77.8 0.0 2.2 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KEZ41389.1 - 1.4e-18 67.2 3.0 6.2e-09 35.7 0.4 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEZ41389.1 - 7.8e-18 64.6 0.3 2.8e-09 36.8 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KEZ41389.1 - 2.7e-13 49.8 0.0 1.3e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KEZ41389.1 - 1.8e-07 31.3 1.8 0.0008 19.5 0.2 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KEZ41389.1 - 7.2e-06 25.9 0.7 0.095 12.5 0.1 3.2 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KEZ41389.1 - 0.00014 21.5 0.1 0.064 12.8 0.1 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Peptidase_C26 PF07722.13 KEZ41389.1 - 0.00053 19.8 0.0 0.22 11.2 0.0 2.9 3 0 0 3 3 3 1 Peptidase C26 DJ-1_PfpI PF01965.24 KEZ41389.1 - 0.0019 18.0 0.0 0.3 10.9 0.0 3.7 3 0 0 3 3 3 1 DJ-1/PfpI family PNP_phzG_C PF10590.9 KEZ41390.1 - 7.1e-22 77.2 1.0 2.8e-21 75.3 1.1 2.0 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KEZ41390.1 - 8.6e-18 64.3 0.0 1.5e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KEZ41390.1 - 0.0058 17.2 0.0 0.02 15.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M28 PF04389.17 KEZ41391.1 - 1.1e-28 100.3 0.0 1.8e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KEZ41391.1 - 3.6e-07 30.1 0.0 7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AFG1_ATPase PF03969.16 KEZ41392.1 - 6.9e-96 321.3 0.0 8e-92 307.9 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KEZ41392.1 - 1.7e-05 25.3 0.1 0.046 14.1 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain Bac_DnaA PF00308.18 KEZ41392.1 - 0.00018 21.4 0.4 0.19 11.6 0.0 2.9 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 KEZ41392.1 - 0.0036 17.3 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ41392.1 - 0.014 15.6 0.0 0.083 13.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ41392.1 - 0.061 13.2 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 KEZ41392.1 - 0.096 13.1 0.0 0.3 11.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KEZ41392.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KEZ41392.1 - 0.15 12.4 0.0 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Cu_bind_like PF02298.17 KEZ41393.1 - 0.0012 18.9 0.4 0.0033 17.4 0.2 1.9 2 0 0 2 2 2 1 Plastocyanin-like domain Copper-bind PF00127.20 KEZ41393.1 - 0.037 14.5 0.5 0.13 12.8 0.5 1.8 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family bZIP_1 PF00170.21 KEZ41394.1 - 0.016 15.3 3.5 0.051 13.7 3.5 1.8 1 0 0 1 1 1 0 bZIP transcription factor Metallophos PF00149.28 KEZ41395.1 - 1.6e-31 110.4 0.0 1.9e-22 80.8 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEZ41395.1 - 0.031 14.7 0.1 0.083 13.3 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain FAM176 PF14851.6 KEZ41396.1 - 2.5 7.7 6.5 1.4 8.6 0.6 2.1 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 KEZ41396.1 - 3.8 7.8 11.9 10 6.4 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sld5 PF05916.11 KEZ41398.1 - 1.5e-30 105.9 0.0 2.2e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein SDA1 PF05285.12 KEZ41399.1 - 0.061 12.8 23.0 0.081 12.3 23.0 1.2 1 0 0 1 1 1 0 SDA1 zf-RING_UBOX PF13445.6 KEZ41399.1 - 3.6 7.7 5.9 7.5 6.7 5.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.12 KEZ41399.1 - 4.3 5.4 27.5 5.6 5.0 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family PAN_1 PF00024.26 KEZ41400.1 - 3.8e-09 36.4 0.5 0.00057 19.8 0.1 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 KEZ41400.1 - 2.6e-06 27.2 4.0 0.0016 18.3 1.2 2.4 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 KEZ41400.1 - 0.007 16.5 4.7 0.026 14.6 0.7 2.4 2 0 0 2 2 2 1 PAN-like domain PQ-loop PF04193.14 KEZ41401.1 - 6.4e-13 48.3 1.3 1.4e-12 47.1 0.6 1.9 1 1 1 2 2 2 1 PQ loop repeat DUF2070 PF09843.9 KEZ41401.1 - 0.16 10.2 3.2 0.2 9.9 3.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_5_2 PF16079.5 KEZ41401.1 - 1.9 8.9 6.2 0.66 10.3 2.6 2.1 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V MMS1_N PF10433.9 KEZ41402.1 - 5.4e-107 358.4 0.0 7.8e-107 357.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KEZ41402.1 - 5.2e-52 177.2 0.0 5.9e-51 173.7 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region Cuticle_1 PF08140.11 KEZ41402.1 - 0.076 13.1 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Rieske PF00355.26 KEZ41403.1 - 1.9e-11 43.7 0.0 3.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KEZ41403.1 - 3.7e-10 40.1 0.1 8.2e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region ProRS-C_1 PF09180.11 KEZ41405.1 - 4.7e-24 84.4 0.2 1e-23 83.3 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KEZ41405.1 - 3.9e-20 72.5 0.0 7.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEZ41405.1 - 1.5e-16 60.3 0.0 4.9e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain DUF919 PF06034.11 KEZ41405.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Unstab_antitox PF09720.10 KEZ41405.1 - 0.53 10.4 3.4 22 5.2 0.1 2.8 3 0 0 3 3 3 0 Putative addiction module component MT0933_antitox PF14013.6 KEZ41405.1 - 1.3 9.3 8.1 3.4 8.1 6.0 2.6 2 0 0 2 2 2 0 MT0933-like antitoxin protein Cpn60_TCP1 PF00118.24 KEZ41406.1 - 1.3e-152 508.9 13.2 1.5e-152 508.7 13.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TMEM154 PF15102.6 KEZ41407.1 - 0.033 14.1 0.5 0.061 13.2 0.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KEZ41407.1 - 0.06 14.2 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain stn_TNFRSF12A PF12191.8 KEZ41407.1 - 0.093 13.0 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SKG6 PF08693.10 KEZ41407.1 - 0.13 11.7 0.2 0.4 10.1 0.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.11 KEZ41407.1 - 0.47 9.8 0.6 0.66 9.3 0.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mucin PF01456.17 KEZ41407.1 - 8.8 6.3 24.0 0.24 11.4 16.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein RTA1 PF04479.13 KEZ41408.1 - 5.2e-52 176.5 2.2 6.3e-52 176.2 2.2 1.1 1 0 0 1 1 1 1 RTA1 like protein 7tm_1 PF00001.21 KEZ41408.1 - 0.071 12.4 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Peptidase_S49_N PF08496.10 KEZ41408.1 - 5.4 7.1 6.7 11 6.1 6.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ion_trans PF00520.31 KEZ41409.1 - 2.5e-09 36.8 23.0 4.8e-09 35.8 23.0 1.4 1 0 0 1 1 1 1 Ion transport protein Peptidase_S9 PF00326.21 KEZ41410.1 - 1.3e-44 152.3 0.0 1.8e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEZ41410.1 - 0.00088 19.2 0.0 0.019 14.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KEZ41410.1 - 0.012 15.7 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.7 KEZ41410.1 - 0.017 15.7 10.1 0.069 13.7 10.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Integrase_Zn PF02022.19 KEZ41410.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain PAF-AH_p_II PF03403.13 KEZ41410.1 - 0.18 10.3 0.0 0.41 9.1 0.0 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 KEZ41410.1 - 0.19 10.3 0.0 0.95 8.1 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) EAP30 PF04157.16 KEZ41411.1 - 6.6e-43 146.7 0.2 8.4e-43 146.3 0.2 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KEZ41411.1 - 1.8e-20 72.9 0.0 3.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KEZ41411.1 - 0.0092 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain SAC3_GANP PF03399.16 KEZ41412.1 - 5e-24 85.2 0.8 6e-22 78.4 0.8 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KEZ41412.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.6 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 KEZ41413.1 - 4.1e-28 96.7 0.0 2.4e-13 49.5 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KEZ41413.1 - 2e-17 62.8 0.1 7.4e-08 32.1 0.0 3.2 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KEZ41413.1 - 1.9e-14 53.6 0.1 5.3e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.17 KEZ41413.1 - 2e-10 40.2 0.0 3.2e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 KEZ41413.1 - 9.4e-10 38.3 0.1 1.7e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.8 KEZ41413.1 - 0.0081 16.0 0.0 0.024 14.4 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Thymidylat_synt PF00303.19 KEZ41414.1 - 7.3e-110 366.3 0.0 8.4e-110 366.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase adh_short PF00106.25 KEZ41415.1 - 1.3e-43 148.7 0.1 1.7e-43 148.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41415.1 - 1.8e-32 112.8 0.0 2.3e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41415.1 - 5.2e-07 29.7 0.1 7.9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEZ41415.1 - 2.8e-05 24.1 0.4 4.6e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEZ41415.1 - 0.00092 19.5 0.1 0.0014 18.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KEZ41415.1 - 0.0021 17.6 0.1 0.0039 16.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 KEZ41415.1 - 0.0039 17.2 0.1 0.0088 16.0 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KEZ41415.1 - 0.021 15.1 0.1 0.037 14.3 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 KEZ41415.1 - 0.11 11.9 0.2 0.17 11.3 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ41415.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ATP19 PF11022.8 KEZ41416.1 - 9.9e-28 96.3 0.0 1.1e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 KEZ41417.1 - 1.1e-79 266.3 0.0 1.4e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 KEZ41418.1 - 9.4e-16 57.7 19.9 9.7e-10 38.5 9.8 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 KEZ41418.1 - 0.17 12.1 11.9 0.075 13.3 4.5 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Rad4 PF03835.15 KEZ41419.1 - 4.7e-35 120.4 0.1 1.4e-34 118.9 0.1 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KEZ41419.1 - 2.5e-26 91.9 0.5 7.4e-26 90.4 0.5 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KEZ41419.1 - 3.9e-20 71.4 0.3 7.1e-20 70.6 0.3 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KEZ41419.1 - 7e-14 52.5 0.3 7e-14 52.5 0.3 6.1 6 0 0 6 6 6 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KEZ41419.1 - 0.015 15.7 0.0 0.076 13.5 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like superfamily IBR PF01485.21 KEZ41420.1 - 7.1 6.9 15.8 0.37 11.1 6.0 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Dcc1 PF09724.9 KEZ41421.1 - 1.1e-11 44.6 0.0 1.3e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RhoGEF PF00621.20 KEZ41422.1 - 4.8e-26 92.1 0.4 4e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 KEZ41422.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Nod1 PF17114.5 KEZ41422.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 IFT57 PF10498.9 KEZ41422.1 - 0.13 11.2 5.5 0.23 10.4 5.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ApoLp-III PF07464.11 KEZ41422.1 - 6.2 6.9 10.0 3.9 7.6 4.6 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) HORMA PF02301.18 KEZ41423.1 - 3.1e-12 46.6 0.0 5.5e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 HORMA domain PI31_Prot_N PF11566.8 KEZ41424.1 - 2.1e-59 200.0 0.0 2.5e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KEZ41424.1 - 6.6e-19 68.9 19.5 6.6e-19 68.9 19.5 3.1 3 1 0 3 3 3 1 PI31 proteasome regulator IBN_N PF03810.19 KEZ41425.1 - 1.2e-12 47.6 0.4 2.7e-11 43.2 0.0 3.5 4 1 1 5 5 5 1 Importin-beta N-terminal domain SQS_PSY PF00494.19 KEZ41425.1 - 8e-05 22.3 0.2 0.00017 21.2 0.2 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase HEAT PF02985.22 KEZ41425.1 - 0.0015 18.6 3.2 0.93 9.9 0.1 5.2 5 0 0 5 5 5 1 HEAT repeat DRIM PF07539.12 KEZ41425.1 - 0.026 12.8 0.5 0.77 8.0 0.0 3.2 4 0 0 4 4 4 0 Down-regulated in metastasis CAS_CSE1 PF03378.15 KEZ41425.1 - 0.035 12.6 0.0 0.07 11.6 0.0 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Cse1 PF08506.10 KEZ41425.1 - 0.049 12.5 0.0 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 Cse1 DUF1617 PF07761.12 KEZ41426.1 - 0.032 14.3 0.1 0.058 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) DUF2742 PF10888.8 KEZ41426.1 - 0.051 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Nucleo_P87 PF07267.11 KEZ41426.1 - 7.3 5.3 10.3 11 4.7 10.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Metallophos PF00149.28 KEZ41428.1 - 1.4e-36 127.0 0.3 1.9e-36 126.5 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEZ41428.1 - 0.037 14.5 0.4 0.096 13.2 0.4 1.8 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KEZ41428.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rho_GDI PF02115.17 KEZ41429.1 - 2.3e-66 223.3 0.3 2.5e-66 223.2 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 KEZ41430.1 - 0.0036 17.1 1.6 0.012 15.4 0.0 2.5 2 2 1 3 3 3 1 KilA-N domain NAD_binding_2 PF03446.15 KEZ41431.1 - 2.6e-32 112.2 0.0 4.1e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KEZ41431.1 - 7.4e-29 100.5 0.0 1.1e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 KEZ41431.1 - 7.7e-07 28.3 0.4 1.2e-06 27.7 0.4 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 3HCDH_N PF02737.18 KEZ41431.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RTA1 PF04479.13 KEZ41432.1 - 4.1e-66 222.5 2.4 5.3e-66 222.2 2.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Adaptin_N PF01602.20 KEZ41433.1 - 4.1e-101 339.1 0.0 5.1e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEZ41433.1 - 2e-15 57.2 0.0 1.6e-14 54.3 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ41433.1 - 4.7e-08 33.3 12.2 7e-05 23.1 0.1 5.2 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KEZ41433.1 - 6.4e-07 29.1 0.4 0.12 12.7 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KEZ41433.1 - 0.0026 18.2 7.0 0.07 13.7 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.7 KEZ41433.1 - 0.0056 16.9 2.3 0.47 10.8 0.1 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion NOA36 PF06524.12 KEZ41433.1 - 2.1 7.6 21.1 4.8 6.4 21.1 1.5 1 0 0 1 1 1 0 NOA36 protein Nuf2 PF03800.14 KEZ41435.1 - 5.3e-42 143.2 0.1 1.6e-41 141.7 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 KEZ41435.1 - 1.7e-34 118.4 16.7 1.7e-34 118.4 16.7 4.3 3 2 2 5 5 5 1 Designed helical repeat protein 10 domain Vg_Tdu PF07545.14 KEZ41435.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Vestigial/Tondu family DUF4360 PF14273.6 KEZ41436.1 - 1.8e-21 76.8 0.8 2e-21 76.7 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) HAD PF12710.7 KEZ41437.1 - 2.1e-24 86.9 0.1 2.7e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KEZ41437.1 - 0.0063 15.9 0.0 0.054 12.9 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 KEZ41437.1 - 0.012 15.9 0.0 0.49 10.6 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KEZ41437.1 - 0.042 13.3 0.0 0.15 11.6 0.0 1.9 2 1 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) DAO PF01266.24 KEZ41438.1 - 2.5e-30 106.2 0.6 3.2e-30 105.9 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Globin PF00042.22 KEZ41438.1 - 0.063 13.8 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Globin Thioredoxin PF00085.20 KEZ41439.1 - 3.2e-26 91.3 0.0 3.7e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEZ41439.1 - 2.1e-08 34.6 0.1 5e-07 30.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEZ41439.1 - 3.3e-06 27.3 0.0 0.007 16.7 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KEZ41439.1 - 5.5e-06 26.2 0.0 6.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KEZ41439.1 - 4e-05 23.1 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KEZ41439.1 - 0.00022 21.4 0.0 0.00035 20.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KEZ41439.1 - 0.00095 18.9 0.1 0.037 13.7 0.0 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 KEZ41439.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.4 1 1 1 2 2 2 1 AhpC/TSA family TraF PF13728.6 KEZ41439.1 - 0.013 15.3 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein WH1 PF00568.23 KEZ41439.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 WH1 domain eIF-1a PF01176.19 KEZ41440.1 - 9.6e-13 47.7 0.1 1.3e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 KEZ41441.1 - 2.9e-139 464.5 14.4 3.4e-139 464.3 14.4 1.0 1 0 0 1 1 1 1 ALG3 protein Pkinase PF00069.25 KEZ41442.1 - 5.4e-60 203.0 0.0 9.8e-60 202.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41442.1 - 1.1e-34 119.9 0.0 1.8e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KEZ41442.1 - 5.5e-24 84.1 26.3 2.7e-13 49.8 3.2 2.9 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.24 KEZ41442.1 - 8.3e-14 52.0 1.3 8.3e-14 52.0 1.3 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain C1_1 PF00130.22 KEZ41442.1 - 2.5e-12 46.5 26.3 4.2e-12 45.8 10.4 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KEZ41442.1 - 0.00018 21.7 0.0 0.00035 20.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KEZ41442.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PHD PF00628.29 KEZ41442.1 - 0.066 13.1 8.1 0.16 11.9 8.1 1.6 1 0 0 1 1 1 0 PHD-finger PAT1 PF09770.9 KEZ41442.1 - 0.3 9.3 20.6 0.53 8.5 20.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 KEZ41442.1 - 1.1 9.1 40.8 3.1 7.7 40.8 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acyl-CoA_dh_1 PF00441.24 KEZ41443.1 - 5.1e-41 140.4 3.9 8.8e-41 139.6 3.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ41443.1 - 7.7e-30 103.9 0.2 4.1e-29 101.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ41443.1 - 8.8e-23 80.3 0.0 2.1e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ41443.1 - 1.4e-16 61.0 1.0 2.7e-16 60.1 1.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KEZ41443.1 - 2.5e-05 24.1 0.1 6.5e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosom_S12_S23 PF00164.25 KEZ41444.1 - 2.9e-29 101.0 0.9 3.9e-29 100.6 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CTD_bind PF04818.13 KEZ41444.1 - 0.2 12.5 0.0 0.32 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Sin_N PF04801.13 KEZ41445.1 - 6.8e-19 68.4 0.0 9.3e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region DUF3720 PF12517.8 KEZ41445.1 - 0.35 11.8 0.1 0.35 11.8 0.1 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3720) PAT1 PF09770.9 KEZ41446.1 - 0 1225.1 0.7 0 1224.9 0.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 T3SS_needle_F PF09392.10 KEZ41446.1 - 0.08 13.1 0.4 0.27 11.4 0.4 1.9 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Glyco_transf_15 PF01793.16 KEZ41447.1 - 1.6e-129 431.9 8.6 1.9e-129 431.6 8.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EMP70 PF02990.16 KEZ41448.1 - 7.4e-203 674.9 7.0 1.1e-202 674.3 7.0 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Med4 PF10018.9 KEZ41449.1 - 2e-41 141.8 5.7 3.1e-41 141.2 5.7 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4763 PF15960.5 KEZ41449.1 - 0.0031 16.9 1.0 0.0031 16.9 1.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4763) UDPG_MGDP_dh_C PF03720.15 KEZ41449.1 - 0.053 13.9 0.4 0.12 12.8 0.4 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Baculo_PEP_C PF04513.12 KEZ41449.1 - 0.42 10.7 2.2 3.9 7.5 2.2 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus QCR10 PF09796.9 KEZ41450.1 - 6.8e-21 74.1 0.2 8.5e-21 73.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DIE2_ALG10 PF04922.12 KEZ41451.1 - 7.3e-91 305.4 7.2 2.3e-90 303.7 7.2 1.6 1 1 0 1 1 1 1 DIE2/ALG10 family U-box PF04564.15 KEZ41452.1 - 1.2e-19 70.2 0.0 2.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 KEZ41452.1 - 3.8e-07 29.6 4.3 4.5e-05 23.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ41452.1 - 4.9e-07 29.7 2.2 0.00054 20.2 0.8 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ41452.1 - 7.8e-06 25.6 3.3 0.14 12.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KEZ41452.1 - 0.00039 21.1 11.7 0.0012 19.6 11.7 1.8 1 1 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_11 PF13414.6 KEZ41452.1 - 0.004 16.8 0.8 6.2 6.6 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 KEZ41452.1 - 0.016 15.4 1.4 0.58 10.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 KEZ41452.1 - 0.018 15.1 0.0 0.074 13.2 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Fis1_TPR_C PF14853.6 KEZ41452.1 - 0.024 14.7 1.0 3.8 7.7 0.4 2.7 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 KEZ41452.1 - 0.034 14.4 2.0 0.51 10.7 1.6 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ41452.1 - 0.042 14.4 1.1 0.13 12.8 1.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ras PF00071.22 KEZ41453.1 - 1.2e-14 54.2 0.0 6.2e-06 25.9 0.0 3.5 3 1 0 3 3 3 3 Ras family Roc PF08477.13 KEZ41453.1 - 0.11 12.7 0.0 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PTR2 PF00854.21 KEZ41454.1 - 3.5e-54 184.2 9.2 5.9e-54 183.4 9.2 1.3 1 0 0 1 1 1 1 POT family DUF4396 PF14342.6 KEZ41454.1 - 0.016 15.6 0.9 0.016 15.6 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Adipogenin PF15202.6 KEZ41454.1 - 3.2 7.8 4.3 51 4.0 0.0 3.2 3 0 0 3 3 3 0 Adipogenin Peptidase_C14 PF00656.22 KEZ41455.1 - 1.6e-60 205.2 0.0 1.9e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Ank_2 PF12796.7 KEZ41456.1 - 1.2e-24 86.7 0.0 4.4e-10 40.0 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ41456.1 - 6.6e-21 72.2 4.3 0.00013 22.1 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 KEZ41456.1 - 1.9e-20 72.6 0.4 7.9e-08 32.4 0.0 4.2 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KEZ41456.1 - 3.1e-17 62.1 6.1 0.00098 19.5 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KEZ41456.1 - 1.4e-16 60.6 5.1 2.1e-06 28.2 0.0 6.3 4 1 4 8 8 8 4 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 KEZ41456.1 - 4.3e-05 22.9 0.1 0.00011 21.6 0.1 1.5 1 1 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 KEZ41456.1 - 0.00025 21.5 0.0 0.0027 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ41456.1 - 0.00029 21.1 0.0 0.0019 18.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 KEZ41456.1 - 0.005 16.8 0.0 0.019 14.9 0.0 2.0 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KEZ41456.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MIT_C PF16565.5 KEZ41456.1 - 0.19 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT NIBRIN_BRCT_II PF16508.5 KEZ41457.1 - 3.4e-37 127.4 0.0 2.4e-36 124.7 0.0 2.4 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KEZ41457.1 - 7.2e-12 45.5 0.1 1.5e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEZ41457.1 - 6.6e-05 23.2 0.1 0.001 19.3 0.1 2.5 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 PF16770.5 KEZ41457.1 - 0.00088 19.1 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain TPR_10 PF13374.6 KEZ41458.1 - 5.5e-44 146.9 0.2 1.2e-12 47.3 0.0 4.9 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ41458.1 - 2.4e-39 133.5 2.9 2.1e-16 60.0 0.0 5.2 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ41458.1 - 2.9e-11 42.9 1.1 0.23 11.9 0.0 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ41458.1 - 4.3e-11 42.0 1.7 0.00048 20.0 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ41458.1 - 2.4e-07 30.7 0.0 0.77 10.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ41458.1 - 2.7e-07 30.2 0.1 0.25 11.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ41458.1 - 2.4e-06 28.1 0.0 0.84 10.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ41458.1 - 9.5e-06 25.2 4.2 0.19 11.6 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ41458.1 - 0.00027 21.4 0.6 2.1 8.9 0.0 3.6 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ41458.1 - 0.00033 20.1 0.2 0.00056 19.4 0.2 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 KEZ41458.1 - 0.0014 18.7 1.8 3.9 7.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ41458.1 - 0.045 14.4 2.3 60 4.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ41458.1 - 0.074 12.8 2.2 5.1 6.9 0.3 3.2 3 0 0 3 3 3 0 TPR repeat PPR PF01535.20 KEZ41458.1 - 0.1 12.9 0.0 12 6.4 0.0 2.8 2 0 0 2 2 2 0 PPR repeat Epimerase PF01370.21 KEZ41460.1 - 1.3e-15 57.5 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ41460.1 - 8.7e-14 51.3 0.0 2.2e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEZ41460.1 - 0.00015 21.0 0.0 0.00051 19.3 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEZ41460.1 - 0.00016 21.2 0.0 0.0012 18.3 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ41460.1 - 0.00094 18.3 0.0 0.0026 16.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Macro PF01661.21 KEZ41460.1 - 0.026 14.5 0.1 0.12 12.4 0.0 2.2 3 1 0 3 3 3 0 Macro domain DnaJ-X PF14308.6 KEZ41461.1 - 4.1e-76 255.1 0.7 4.1e-76 255.1 0.7 1.5 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KEZ41461.1 - 1.6e-26 92.2 0.9 3.2e-26 91.2 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain SQS_PSY PF00494.19 KEZ41462.1 - 7.5e-34 117.4 0.0 1.3e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase PyocinActivator PF11112.8 KEZ41462.1 - 0.13 12.4 0.1 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Pyocin activator protein PrtN Peptidase_S8 PF00082.22 KEZ41463.1 - 5.1e-32 111.3 12.9 7.9e-32 110.7 12.9 1.3 1 0 0 1 1 1 1 Subtilase family F-box-like PF12937.7 KEZ41464.1 - 0.00036 20.4 0.0 0.002 18.0 0.0 2.3 2 1 0 2 2 2 1 F-box-like Mannosyl_trans PF05007.13 KEZ41465.1 - 2.5e-75 253.7 11.2 3.5e-75 253.2 11.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KEZ41465.1 - 1.3e-12 47.5 0.7 1.3e-12 47.5 0.7 2.5 1 1 0 2 2 2 1 GPI transamidase subunit PIG-U MtrE PF04206.12 KEZ41465.1 - 0.52 9.6 6.7 0.051 12.9 0.9 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E GT87 PF09594.10 KEZ41465.1 - 1.9 8.1 34.0 0.024 14.4 24.0 2.7 1 1 1 2 2 2 0 Glycosyltransferase family 87 Translin PF01997.16 KEZ41466.1 - 2.2e-51 174.8 0.0 2.6e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Translin family KCNQ2_u3 PF16642.5 KEZ41466.1 - 0.029 15.3 0.0 0.057 14.4 0.0 1.4 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 adh_short PF00106.25 KEZ41467.1 - 4e-37 127.6 0.0 5.4e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41467.1 - 4.2e-34 118.1 0.0 5.8e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41467.1 - 4.6e-13 49.5 0.2 6.6e-13 49.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Peripla_BP_6 PF13458.6 KEZ41467.1 - 0.0045 16.7 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Epimerase PF01370.21 KEZ41467.1 - 0.11 11.9 0.1 0.38 10.2 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ41467.1 - 0.23 10.6 0.0 0.42 9.7 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3123 PF11321.8 KEZ41467.1 - 0.78 10.4 4.6 6.7 7.4 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3123) Gpr1_Fun34_YaaH PF01184.19 KEZ41469.1 - 3.4e-88 294.6 15.4 4.2e-88 294.3 15.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Herpes_LMP1 PF05297.11 KEZ41470.1 - 0.059 12.6 1.0 0.067 12.4 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) 7TMR-DISM_7TM PF07695.11 KEZ41470.1 - 0.076 12.9 17.6 0.88 9.4 2.4 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Myc_target_1 PF15179.6 KEZ41470.1 - 0.78 9.6 7.7 4.1 7.3 2.4 2.1 2 0 0 2 2 2 0 Myc target protein 1 Tetraspanin PF00335.20 KEZ41470.1 - 1.1 8.9 8.6 10 5.7 8.6 2.1 1 1 0 1 1 1 0 Tetraspanin family MARVEL PF01284.23 KEZ41470.1 - 1.9 8.5 20.2 2.5 8.1 20.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2339 PF10101.9 KEZ41470.1 - 9.4 4.7 14.4 12 4.3 14.4 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) p450 PF00067.22 KEZ41471.1 - 6.2e-55 186.8 0.0 7.6e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SopA PF13981.6 KEZ41471.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 SopA-like central domain PhyH PF05721.13 KEZ41472.1 - 0.00021 21.6 0.0 0.00049 20.4 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KEZ41472.1 - 0.0038 16.1 0.0 0.2 10.4 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 KEZ41472.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Zn_clus PF00172.18 KEZ41473.1 - 0.016 15.3 2.2 0.047 13.8 2.2 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S15 PF02129.18 KEZ41474.1 - 6.2e-39 134.2 0.3 2.6e-33 115.8 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KEZ41474.1 - 2.3e-20 73.5 0.0 3.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Sugar_tr PF00083.24 KEZ41475.1 - 2.2e-84 283.9 25.7 2.6e-84 283.7 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41475.1 - 8.9e-31 107.1 38.9 1.1e-28 100.2 30.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pectate_lyase_3 PF12708.7 KEZ41476.1 - 2.3e-74 249.9 5.4 1.7e-69 234.0 1.2 2.8 2 1 0 2 2 2 2 Pectate lyase superfamily protein HRXXH PF13933.6 KEZ41477.1 - 0.0034 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KEZ41477.1 - 0.0041 17.7 0.0 0.0088 16.6 0.0 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase adh_short_C2 PF13561.6 KEZ41479.1 - 4.6e-58 196.5 0.5 5.6e-58 196.3 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ41479.1 - 4.8e-48 163.2 0.2 6.3e-48 162.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ41479.1 - 3.2e-12 46.7 0.3 4.8e-12 46.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 KEZ41479.1 - 0.031 14.4 0.1 0.093 12.8 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain SnoaL_3 PF13474.6 KEZ41480.1 - 1.4e-06 28.6 0.0 3.6e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 KEZ41480.1 - 0.083 13.3 0.3 0.13 12.7 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Pyr_redox_2 PF07992.14 KEZ41481.1 - 1.9e-11 43.8 0.0 2.9e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEZ41481.1 - 3.5e-11 42.2 0.0 5e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ41481.1 - 1.7e-08 34.1 0.0 8.1e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ41481.1 - 4.3e-08 32.7 0.0 2.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEZ41481.1 - 9.2e-08 32.2 0.0 8.1e-07 29.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEZ41481.1 - 0.0013 18.8 0.0 0.3 11.1 0.1 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding TetR PF13972.6 KEZ41481.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial transcriptional repressor FAD_binding_2 PF00890.24 KEZ41481.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KEZ41481.1 - 0.011 15.3 0.2 4.1 6.9 0.0 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KEZ41481.1 - 0.021 14.2 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ41481.1 - 0.074 13.1 0.0 0.39 10.8 0.0 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KEZ41481.1 - 0.13 12.7 0.0 0.53 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KEZ41481.1 - 0.16 12.6 0.0 11 6.6 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ41481.1 - 0.21 10.8 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 KEZ41481.1 - 0.23 10.7 0.0 0.62 9.2 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_1 PF00561.20 KEZ41482.1 - 3.2e-14 53.2 0.0 2.7e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ41482.1 - 1.3e-12 47.5 0.0 3.2e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ41482.1 - 1.6e-12 48.5 0.1 2.5e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 KEZ41482.1 - 0.0011 19.0 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 KEZ41482.1 - 0.018 14.9 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase PF00151.19 KEZ41482.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Lipase Thioesterase PF00975.20 KEZ41482.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 KEZ41482.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase NMT_C PF02799.15 KEZ41483.1 - 1.8e-81 272.7 0.0 2.8e-81 272.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KEZ41483.1 - 2e-70 235.8 0.0 1.9e-69 232.6 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KEZ41483.1 - 6.1e-06 26.3 0.6 0.005 16.9 0.0 3.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Med3 PF11593.8 KEZ41483.1 - 0.15 11.2 2.6 0.22 10.6 2.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal eIF-3c_N PF05470.12 KEZ41483.1 - 0.68 8.2 8.1 1.1 7.5 8.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Cnd1_N PF12922.7 KEZ41483.1 - 1.2 9.0 3.3 2.6 7.9 3.3 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term PGA2 PF07543.12 KEZ41483.1 - 1.6 8.7 9.1 3.3 7.7 9.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CCDC106 PF15794.5 KEZ41483.1 - 3.7 7.2 7.2 7.4 6.2 7.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 KEZ41483.1 - 6.5 4.9 6.8 9.9 4.3 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_6 PF12697.7 KEZ41484.1 - 3e-11 44.4 0.1 3.8e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ41484.1 - 5.2e-10 39.0 0.0 1.7e-09 37.3 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ41484.1 - 7.9e-08 32.2 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KEZ41484.1 - 7.3e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KEZ41484.1 - 0.0021 16.8 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 KEZ41484.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEZ41484.1 - 0.043 13.4 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIP PF03583.14 KEZ41484.1 - 0.097 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.16 KEZ41484.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HIG_1_N PF04588.13 KEZ41486.1 - 4.9e-21 74.7 0.4 7.8e-21 74.1 0.4 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PALP PF00291.25 KEZ41487.1 - 4.4e-72 243.0 0.3 6.5e-72 242.4 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KEZ41487.1 - 1.3e-39 133.9 0.0 2.4e-20 72.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.18 KEZ41488.1 - 3.5e-21 75.1 10.9 5.2e-21 74.6 10.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L35p PF01632.19 KEZ41488.1 - 0.45 11.1 5.7 1.1 9.9 5.7 1.7 1 1 0 1 1 1 0 Ribosomal protein L35 Acetyltransf_1 PF00583.25 KEZ41489.1 - 2.4e-13 50.3 0.0 3.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ41489.1 - 5.6e-07 29.9 0.0 8.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ41489.1 - 6.3e-07 29.4 0.0 8.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ41489.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KEZ41489.1 - 0.00039 20.6 0.0 0.0017 18.5 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ41489.1 - 0.016 15.8 0.0 0.02 15.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2156 PF09924.9 KEZ41489.1 - 0.052 12.5 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2156) MutS_V PF00488.21 KEZ41490.1 - 2.5e-67 226.6 0.7 5.1e-67 225.6 0.1 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KEZ41490.1 - 6.7e-41 140.6 0.1 1.4e-40 139.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KEZ41490.1 - 1.9e-32 111.8 0.0 1e-31 109.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KEZ41490.1 - 6.1e-16 59.0 0.0 2.1e-15 57.2 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KEZ41490.1 - 2.7e-14 53.3 0.3 6e-14 52.2 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 KEZ41490.1 - 0.025 14.2 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEZ41490.1 - 0.027 15.0 1.9 0.064 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ41490.1 - 0.036 13.8 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3176 PF11374.8 KEZ41491.1 - 9.9e-24 83.6 0.9 9.9e-24 83.6 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) CTD PF12815.7 KEZ41491.1 - 0.0008 19.9 6.7 0.0058 17.2 0.7 2.8 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 HEAT_2 PF13646.6 KEZ41493.1 - 1.4e-47 160.0 52.9 4e-13 49.6 3.2 6.2 2 1 6 8 8 8 7 HEAT repeats HEAT PF02985.22 KEZ41493.1 - 4.8e-29 97.9 17.5 0.0012 18.9 0.0 10.9 11 0 0 11 11 11 8 HEAT repeat HEAT_EZ PF13513.6 KEZ41493.1 - 7.6e-29 99.8 36.3 0.00028 21.3 0.3 10.8 6 2 4 10 10 10 7 HEAT-like repeat Cnd1 PF12717.7 KEZ41493.1 - 5.8e-19 68.7 0.0 0.00046 20.3 0.0 6.9 2 1 5 7 7 6 4 non-SMC mitotic condensation complex subunit 1 NACHT PF05729.12 KEZ41493.1 - 2.6e-16 60.0 0.0 6.3e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Arm PF00514.23 KEZ41493.1 - 6.5e-13 48.2 25.0 0.087 12.9 0.2 9.9 7 3 3 10 10 10 4 Armadillo/beta-catenin-like repeat NB-ARC PF00931.22 KEZ41493.1 - 5.8e-08 32.2 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NLRC4_HD2 PF17776.1 KEZ41493.1 - 8.8e-07 29.5 0.1 2.3e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 NLRC4 helical domain HD2 AAA_22 PF13401.6 KEZ41493.1 - 1.2e-05 25.6 0.0 6.1e-05 23.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain Adaptin_N PF01602.20 KEZ41493.1 - 5.4e-05 21.9 0.1 1.6 7.2 0.0 3.8 2 1 3 5 5 4 2 Adaptin N terminal region DUF484 PF04340.12 KEZ41493.1 - 0.00019 21.2 1.3 18 4.9 0.0 4.3 3 1 1 4 4 4 0 Protein of unknown function, DUF484 Vac14_Fab1_bd PF12755.7 KEZ41493.1 - 0.00048 20.7 0.0 53 4.5 0.0 6.1 3 3 2 6 6 6 0 Vacuolar 14 Fab1-binding region GAIN_A PF18619.1 KEZ41493.1 - 0.00059 20.0 7.5 38 4.6 0.0 8.1 9 0 0 9 9 9 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A CLASP_N PF12348.8 KEZ41493.1 - 0.0016 18.0 1.2 29 4.1 0.0 5.5 4 2 1 5 5 5 0 CLASP N terminal AAA PF00004.29 KEZ41493.1 - 0.0027 18.1 0.0 0.0091 16.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ41493.1 - 0.0085 16.5 0.2 0.0085 16.5 0.2 3.8 2 2 0 2 2 2 1 AAA ATPase domain DUF829 PF05705.14 KEZ41493.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) NTPase_1 PF03266.15 KEZ41493.1 - 0.049 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 NTPase PIN_9 PF18477.1 KEZ41493.1 - 0.055 13.8 1.8 74 3.7 0.0 5.0 3 1 2 5 5 5 0 PIN like domain DUF676 PF05057.14 KEZ41493.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Nipped-B_C PF12830.7 KEZ41493.1 - 0.15 12.0 1.1 1.4e+02 2.3 0.0 5.1 6 2 2 8 8 8 0 Sister chromatid cohesion C-terminus DUF4042 PF13251.6 KEZ41493.1 - 0.57 9.9 3.1 72 3.0 0.0 4.9 4 2 2 6 6 5 0 Domain of unknown function (DUF4042) HEAT_PBS PF03130.16 KEZ41493.1 - 1.4 9.8 61.3 11 7.0 0.1 11.6 11 0 0 11 11 11 0 PBS lyase HEAT-like repeat DLH PF01738.18 KEZ41495.1 - 4.7e-30 104.8 0.0 5.5e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KEZ41495.1 - 3.8e-05 23.5 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KEZ41495.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_61 PF03443.14 KEZ41497.1 - 2.1e-48 165.0 0.2 2.5e-48 164.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldedh PF00171.22 KEZ41499.1 - 6.7e-141 469.9 3.4 8.3e-141 469.6 3.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 KEZ41499.1 - 0.11 12.5 1.0 0.46 10.5 0.1 2.3 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Zn_clus PF00172.18 KEZ41500.1 - 1.8e-06 27.9 10.2 3.9e-06 26.9 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ41500.1 - 7.6e-05 21.9 0.6 0.00016 20.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NatB_MDM20 PF09797.9 KEZ41500.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Mst1_SARAH PF11629.8 KEZ41500.1 - 0.71 10.0 2.3 7.4 6.7 0.5 2.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Myb_DNA-bind_3 PF12776.7 KEZ41501.1 - 0.044 14.8 0.5 0.17 12.9 0.6 1.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain TFIIS_M PF07500.14 KEZ41502.1 - 2e-26 92.7 0.9 2e-26 92.7 0.9 1.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KEZ41502.1 - 1.1e-17 63.6 7.7 1.8e-17 62.9 7.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KEZ41502.1 - 4.3e-11 42.7 0.4 1.6e-10 40.9 0.4 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-ZPR1 PF03367.13 KEZ41502.1 - 0.038 13.9 1.5 0.038 13.9 1.5 2.1 3 0 0 3 3 3 0 ZPR1 zinc-finger domain Elf1 PF05129.13 KEZ41502.1 - 0.23 11.5 4.6 0.69 10.0 4.6 1.9 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AP-5_subunit_s1 PF15001.6 KEZ41502.1 - 0.73 9.8 4.1 0.32 11.0 1.1 1.9 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Methyltransf_28 PF02636.17 KEZ41503.1 - 4.1e-41 141.4 0.0 5.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KEZ41503.1 - 3.5e-05 23.7 0.0 9.2e-05 22.4 0.0 1.6 1 1 1 2 2 2 1 PRMT5 arginine-N-methyltransferase RrnaAD PF00398.20 KEZ41503.1 - 0.028 13.5 0.0 0.081 12.0 0.0 1.7 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KEZ41503.1 - 0.074 13.8 0.0 0.52 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_2c PF01411.19 KEZ41504.1 - 1.9e-210 700.1 0.1 1.9e-210 700.1 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KEZ41504.1 - 9.9e-16 57.6 0.1 2.3e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KEZ41504.1 - 2.6e-09 37.6 2.4 8.4e-09 36.0 2.4 1.9 1 0 0 1 1 1 1 DHHA1 domain ChaB PF06150.12 KEZ41504.1 - 0.2 12.2 0.8 4.6 7.9 0.8 3.0 2 0 0 2 2 2 0 ChaB TMEM247 PF15444.6 KEZ41506.1 - 0.00035 20.7 0.8 0.00035 20.7 0.8 1.6 2 0 0 2 2 2 1 Transmembrane protein 247 Mei5 PF10376.9 KEZ41506.1 - 0.021 14.7 7.1 0.23 11.3 7.1 2.5 1 1 0 1 1 1 0 Double-strand recombination repair protein RCR PF12273.8 KEZ41507.1 - 1.5e-13 51.4 6.8 2.4e-13 50.8 6.8 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Glyco_transf_28 PF03033.20 KEZ41508.1 - 3.2e-19 69.4 0.5 3.7e-11 43.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UIM PF02809.20 KEZ41508.1 - 2.7e-06 26.9 43.5 0.0056 16.5 0.5 8.3 8 0 0 8 8 8 5 Ubiquitin interaction motif ATG_C PF09333.11 KEZ41508.1 - 3.5e-06 27.3 0.0 1.3e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KEZ41508.1 - 7.3e-05 21.8 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEZ41508.1 - 0.00054 20.0 0.4 0.0019 18.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Sec61_beta PF03911.16 KEZ41509.1 - 2.4e-19 69.1 1.9 3.7e-19 68.5 1.9 1.3 1 0 0 1 1 1 1 Sec61beta family NIF PF03031.18 KEZ41510.1 - 3.3e-54 182.9 0.1 4.6e-54 182.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABC_membrane_2 PF06472.15 KEZ41511.1 - 3.9e-92 308.5 1.3 1.4e-91 306.7 0.1 2.3 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KEZ41511.1 - 3.2e-15 56.9 0.0 1e-14 55.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KEZ41511.1 - 0.0077 16.6 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 KEZ41511.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KEZ41511.1 - 0.038 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 KEZ41511.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ41511.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KEZ41511.1 - 0.17 12.3 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KEZ41511.1 - 0.5 10.8 2.9 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.21 KEZ41512.1 - 2.6e-44 151.6 0.0 3.1e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 KEZ41513.1 - 4e-48 160.6 44.0 6.8e-08 32.7 0.7 6.5 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEZ41513.1 - 7.5e-25 86.5 17.5 7.9e-08 32.0 1.9 5.9 3 2 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 KEZ41513.1 - 1.1e-16 60.8 17.0 2.4e-09 37.0 0.3 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KEZ41513.1 - 3.9e-06 26.5 19.0 0.33 11.1 0.3 7.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 KEZ41513.1 - 7.2e-06 25.9 15.2 5.8 7.9 0.1 8.8 9 1 0 9 9 9 2 Leucine Rich Repeat Abhydrolase_3 PF07859.13 KEZ41514.1 - 4.5e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ41514.1 - 0.00022 20.6 0.0 0.046 13.0 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEZ41514.1 - 0.0055 16.2 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ41514.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold FoP_duplication PF13865.6 KEZ41515.1 - 3.2 8.4 15.6 5.7 7.6 15.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SET PF00856.28 KEZ41516.1 - 8e-10 39.3 0.2 1.6e-08 35.2 0.2 2.5 1 1 0 1 1 1 1 SET domain Tox-MPTase5 PF15641.6 KEZ41516.1 - 0.021 14.9 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Nop25 PF09805.9 KEZ41516.1 - 0.44 11.0 9.1 0.13 12.7 4.2 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) F-box-like PF12937.7 KEZ41517.1 - 0.00042 20.2 0.3 0.0011 18.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like UBM PF14377.6 KEZ41517.1 - 0.014 14.9 0.3 0.036 13.5 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Kinetochor_Ybp2 PF08568.10 KEZ41518.1 - 2.6e-106 356.6 0.0 3.6e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin MaoC_dehydratas PF01575.19 KEZ41519.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain eRF1_2 PF03464.15 KEZ41520.1 - 1.1e-47 161.7 0.1 1.8e-47 161.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KEZ41520.1 - 7.7e-39 132.7 0.6 1.8e-38 131.5 0.6 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KEZ41520.1 - 3.1e-21 75.7 0.0 5.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KEZ41520.1 - 4.2e-11 43.2 0.3 1.9e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KEZ41520.1 - 4.7e-09 36.6 0.0 7.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1770 PF08589.10 KEZ41521.1 - 6.8e-25 87.9 2.3 6.3e-23 81.6 2.3 2.1 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 KEZ41522.1 - 4.1e-05 23.0 0.0 9.3e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 ParE_toxin PF05016.15 KEZ41522.1 - 0.041 14.5 0.4 0.098 13.3 0.4 1.6 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Pertussis_S1 PF02917.14 KEZ41522.1 - 0.061 13.1 0.3 0.095 12.5 0.3 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 Ebola_NP PF05505.12 KEZ41522.1 - 1.2 7.3 3.9 1.8 6.8 3.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Ribosomal_L2_C PF03947.18 KEZ41523.1 - 1.9e-42 144.4 5.4 3.6e-42 143.5 5.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KEZ41523.1 - 4.6e-17 61.7 0.2 1.4e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 KEZ41524.1 - 1.6e-66 224.7 0.0 1.9e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KEZ41524.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 KEZ41525.1 - 1.5e-30 106.6 1.7 1.6e-30 106.6 0.6 1.5 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KEZ41525.1 - 4.2e-17 63.1 0.3 4.2e-17 63.1 0.3 2.6 3 0 0 3 3 3 1 Telomerase activating protein Est1 RNA12 PF10443.9 KEZ41526.1 - 0.18 10.5 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein zf-C2H2_jaz PF12171.8 KEZ41526.1 - 0.22 11.8 0.2 0.22 11.8 0.2 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KEZ41526.1 - 2.4 8.8 15.0 3.6 8.2 1.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type G10 PF01125.17 KEZ41527.1 - 2.1e-41 141.1 0.1 2.2e-41 141.0 0.1 1.0 1 0 0 1 1 1 1 G10 protein DUF1040 PF06288.13 KEZ41527.1 - 0.043 14.2 0.0 0.084 13.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) Complex1_LYR_2 PF13233.6 KEZ41528.1 - 1.5e-08 35.2 0.1 2e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KEZ41528.1 - 2.1e-06 27.7 0.2 4e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) RNA_pol_L_2 PF13656.6 KEZ41529.1 - 8.1e-32 108.8 0.0 1.1e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KEZ41529.1 - 2.8e-11 42.7 0.0 3.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2205 PF10224.9 KEZ41529.1 - 0.013 15.5 0.2 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Short coiled-coil protein Pkinase PF00069.25 KEZ41531.1 - 1.2e-50 172.3 0.0 1.9e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41531.1 - 1.2e-28 100.1 0.0 1.7e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ41531.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ41531.1 - 0.012 15.6 0.2 0.059 13.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KEZ41531.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEZ41531.1 - 0.097 12.3 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Hamartin PF04388.12 KEZ41531.1 - 6.3 5.3 9.7 7.7 5.0 9.7 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 KEZ41532.1 - 7.4e-57 192.7 0.0 4.3e-51 173.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41532.1 - 5.6e-34 117.6 0.0 5.4e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEZ41532.1 - 3e-07 30.1 0.0 1.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEZ41532.1 - 3.9e-05 23.7 0.0 8.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ41532.1 - 0.00062 18.7 0.5 0.0042 15.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KEZ41532.1 - 0.042 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KEZ41532.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sybindin PF04099.12 KEZ41533.1 - 1.5e-25 89.8 0.0 1.8e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Peroxin-3 PF04882.12 KEZ41534.1 - 1.3e-169 565.1 0.9 1.6e-169 564.8 0.9 1.1 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 KEZ41535.1 - 1.6e-51 174.4 0.0 1.9e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 G-gamma PF00631.22 KEZ41535.1 - 0.22 11.6 0.9 0.91 9.6 0.0 2.3 2 1 0 2 2 2 0 GGL domain EF-hand_4 PF12763.7 KEZ41536.1 - 7.3e-28 96.6 0.0 3.3e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KEZ41536.1 - 0.00011 21.5 0.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KEZ41536.1 - 0.0014 19.1 0.1 0.84 10.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEZ41536.1 - 0.0072 16.2 0.0 6.6 6.9 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 KEZ41536.1 - 0.081 12.8 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair FAD_binding_6 PF00970.24 KEZ41537.1 - 1.2e-29 102.6 0.0 1.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KEZ41537.1 - 4.7e-29 101.2 0.0 6.6e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KEZ41537.1 - 7.3e-05 22.9 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain mRNA_cap_enzyme PF01331.19 KEZ41538.1 - 1.5e-52 178.3 0.6 2.1e-52 177.8 0.6 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KEZ41538.1 - 1.6e-28 99.5 0.0 2.9e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KEZ41538.1 - 2.7e-07 30.5 0.0 0.00024 20.8 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain TPR_2 PF07719.17 KEZ41539.1 - 6.8e-33 110.1 32.9 0.0001 22.1 0.4 13.9 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ41539.1 - 9.3e-27 91.7 34.8 1.8e-05 24.3 0.3 12.7 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ41539.1 - 2.1e-20 71.2 32.9 0.0016 18.5 0.0 13.7 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ41539.1 - 9.9e-18 62.8 18.5 9.9e-05 22.1 0.1 10.6 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ41539.1 - 1e-16 61.3 16.3 0.0054 17.4 0.1 9.3 7 2 1 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ41539.1 - 1.3e-16 60.6 36.4 0.00039 20.7 0.6 11.3 9 4 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ41539.1 - 4.2e-16 59.2 28.7 0.00044 20.7 0.1 11.0 8 4 3 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ41539.1 - 4.8e-14 51.8 36.1 4.8e-05 23.8 0.2 13.0 13 2 2 15 15 13 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ41539.1 - 2.4e-12 46.3 22.9 0.19 11.7 0.0 10.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ41539.1 - 8.8e-11 41.7 26.4 6.3e-05 23.4 0.1 9.8 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ41539.1 - 2.2e-09 37.0 13.8 0.19 12.2 0.2 10.1 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ41539.1 - 9e-09 34.9 33.3 0.054 13.2 0.0 9.4 11 0 0 11 11 11 4 TPR repeat ANAPC3 PF12895.7 KEZ41539.1 - 0.00023 21.3 23.1 0.24 11.6 1.3 6.9 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KEZ41539.1 - 0.0071 16.3 11.7 0.94 9.5 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat PPR PF01535.20 KEZ41539.1 - 0.0076 16.4 0.1 1.8 9.0 0.0 3.9 2 0 0 2 2 2 1 PPR repeat DUF4192 PF13830.6 KEZ41539.1 - 0.075 13.1 0.0 0.075 13.1 0.0 4.8 2 1 0 3 3 1 0 Domain of unknown function (DUF4192) TPR_4 PF07721.14 KEZ41539.1 - 0.12 13.1 0.6 22 6.0 0.0 5.1 5 0 0 5 5 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 KEZ41540.1 - 8.8e-42 141.6 1.1 4.6e-11 43.2 0.0 5.7 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ41540.1 - 2.6e-34 116.8 2.3 3.3e-09 36.8 0.0 6.9 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KEZ41540.1 - 3.3e-31 106.3 4.5 6e-05 23.3 0.5 9.4 9 1 0 9 9 8 6 Ankyrin repeat Ank_4 PF13637.6 KEZ41540.1 - 1.8e-28 98.5 4.0 1.2e-07 32.2 0.2 7.0 5 2 4 9 9 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ41540.1 - 9.9e-28 93.1 0.9 0.0021 18.4 0.0 9.6 11 0 0 11 11 9 5 Ankyrin repeat Patatin PF01734.22 KEZ41540.1 - 3.8e-26 92.6 0.0 7.4e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase NACHT PF05729.12 KEZ41540.1 - 5.2e-09 36.2 0.0 1.3e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ41540.1 - 4.6e-06 27.1 0.1 3.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ41540.1 - 0.0024 18.1 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ41540.1 - 0.0081 16.6 0.0 0.031 14.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KEZ41540.1 - 0.014 15.9 0.0 0.12 13.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEZ41540.1 - 0.021 14.8 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KEZ41540.1 - 0.043 13.0 0.0 0.09 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KEZ41540.1 - 0.048 12.9 0.1 0.91 8.7 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain DUF2075 PF09848.9 KEZ41540.1 - 0.075 12.2 0.0 0.43 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KEZ41540.1 - 0.11 12.2 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEZ41540.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KEZ41540.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PX PF00787.24 KEZ41541.1 - 3.3e-18 65.7 0.0 1.2e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KEZ41541.1 - 5.2e-13 49.1 9.7 4.1e-08 33.1 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF3426 PF11906.8 KEZ41542.1 - 0.083 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) HEAT PF02985.22 KEZ41543.1 - 2.3e-06 27.4 3.3 0.3 11.5 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KEZ41543.1 - 0.00018 21.6 1.5 6 6.9 0.1 4.1 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ41543.1 - 0.00038 20.8 1.0 0.0098 16.3 0.6 3.3 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 KEZ41543.1 - 0.036 14.6 5.3 0.096 13.2 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat DUF3246 PF11596.8 KEZ41543.1 - 0.1 12.0 1.0 0.27 10.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SNF5 PF04855.12 KEZ41544.1 - 6.8e-66 222.4 3.2 4.6e-65 219.7 0.8 2.7 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 KEZ41545.1 - 4.1e-08 33.2 0.1 8.9e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 KEZ41546.1 - 1.1e-14 54.1 23.1 4.6e-08 32.8 10.8 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KEZ41546.1 - 0.0013 18.6 17.4 0.0013 18.5 2.0 2.5 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 KEZ41546.1 - 0.0013 18.9 7.9 0.0038 17.5 0.4 2.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KEZ41546.1 - 0.16 11.5 11.3 0.053 13.1 4.1 2.6 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 KEZ41546.1 - 0.27 10.8 11.5 0.69 9.5 2.9 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 KEZ41546.1 - 10 6.2 12.2 1.9 8.5 3.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Synaptobrevin PF00957.21 KEZ41547.1 - 6.4e-14 51.5 0.6 1.1e-13 50.8 0.6 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEZ41547.1 - 2.4e-09 37.1 0.0 5.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain PUF PF00806.19 KEZ41548.1 - 3.1e-24 83.3 0.0 3.4e-05 23.3 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KEZ41548.1 - 1.6e-13 50.2 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.27 KEZ41549.1 - 1.5e-35 123.2 0.0 4.2e-35 121.7 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KEZ41549.1 - 1e-18 67.0 0.0 3e-18 65.5 0.0 1.9 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KEZ41549.1 - 0.022 14.1 0.0 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) TPR_1 PF00515.28 KEZ41550.1 - 1.3e-30 103.9 18.1 8.5e-06 25.4 0.0 8.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ41550.1 - 9.9e-30 100.2 31.5 2.3e-05 24.2 0.1 10.8 11 1 1 12 12 12 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ41550.1 - 3.2e-28 97.8 11.6 2e-23 82.4 0.4 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KEZ41550.1 - 4.8e-23 79.4 8.7 0.00068 19.6 0.2 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ41550.1 - 2.3e-21 75.2 13.3 8.5e-08 31.8 0.2 8.0 6 2 3 9 9 9 5 TPR repeat TPR_16 PF13432.6 KEZ41550.1 - 9.6e-19 67.8 32.0 7.8e-10 39.2 2.1 8.2 4 3 3 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ41550.1 - 3.3e-18 64.8 24.9 0.036 14.9 0.0 10.0 5 2 7 12 12 12 5 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ41550.1 - 2e-16 60.2 21.4 4.7e-05 23.8 0.4 6.7 6 1 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ41550.1 - 3.5e-15 55.2 10.7 0.034 14.5 0.3 8.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ41550.1 - 5.5e-14 52.1 14.7 0.00072 19.7 1.6 6.1 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ41550.1 - 7.4e-14 50.7 14.6 0.0023 17.8 0.0 9.1 7 1 2 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ41550.1 - 2.2e-10 40.7 23.9 0.0026 18.0 4.1 7.9 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ41550.1 - 3.5e-07 30.4 11.2 17 6.3 0.8 9.0 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ41550.1 - 0.0049 17.4 7.9 5.4 7.9 0.1 6.2 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ41550.1 - 0.0077 15.6 5.8 0.017 14.5 1.9 3.0 1 1 1 3 3 3 1 MalT-like TPR region TPR_10 PF13374.6 KEZ41550.1 - 0.065 13.1 12.9 0.26 11.2 1.2 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF5113 PF17140.4 KEZ41550.1 - 1.1 9.1 4.8 0.86 9.4 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Sel1 PF08238.12 KEZ41550.1 - 2.9 8.7 5.5 29 5.5 0.0 4.1 5 0 0 5 5 3 0 Sel1 repeat Fis1_TPR_C PF14853.6 KEZ41550.1 - 5.7 7.1 15.0 2.4 8.3 0.0 5.4 8 0 0 8 8 5 0 Fis1 C-terminal tetratricopeptide repeat CENP-T_C PF15511.6 KEZ41551.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KEZ41551.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KEZ41551.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KEZ41551.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KEZ41551.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KEZ41551.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KEZ41551.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KEZ41551.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KEZ41551.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Sedlin_N PF04628.13 KEZ41552.1 - 3e-43 147.1 0.0 3.7e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KEZ41552.1 - 0.00015 21.7 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 2 Sybindin-like family Peptidase_C25 PF01364.18 KEZ41552.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 L31 PF09784.9 KEZ41553.1 - 4.7e-46 155.4 0.4 5.2e-46 155.3 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Fez1 PF06818.15 KEZ41553.1 - 0.068 13.6 0.2 0.082 13.3 0.2 1.0 1 0 0 1 1 1 0 Fez1 RRM_1 PF00076.22 KEZ41554.1 - 2.8e-16 59.1 0.0 4.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup54 PF13874.6 KEZ41555.1 - 0.95 9.6 8.9 0.083 13.0 3.4 2.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 EBP PF05241.12 KEZ41557.1 - 1.3e-56 190.9 8.4 1.4e-56 190.7 7.5 1.5 2 0 0 2 2 2 1 Emopamil binding protein LPP PF04728.13 KEZ41557.1 - 0.01 16.2 0.1 1.7 9.1 0.0 2.7 2 0 0 2 2 2 1 Lipoprotein leucine-zipper PI_PP_I PF18363.1 KEZ41557.1 - 0.045 13.9 0.1 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF4635 PF15466.6 KEZ41557.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) NPV_P10 PF05531.12 KEZ41557.1 - 0.27 11.7 0.5 19 5.8 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein 2OG-FeII_Oxy_3 PF13640.6 KEZ41559.1 - 1.9e-07 31.8 0.0 4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PUF PF00806.19 KEZ41560.1 - 4.6e-64 208.7 8.7 3.8e-08 32.6 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 KEZ41560.1 - 0.016 15.0 0.4 26 4.7 0.0 4.2 4 1 0 4 4 4 0 Single Cache domain 2 SapB_2 PF03489.17 KEZ41560.1 - 0.3 11.3 0.9 9 6.5 0.1 2.9 3 0 0 3 3 3 0 Saposin-like type B, region 2 DUF1640 PF07798.11 KEZ41561.1 - 5e-40 137.4 3.0 5e-40 137.4 3.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Nnf1 PF03980.14 KEZ41562.1 - 9e-31 106.5 1.8 2e-30 105.4 0.2 2.1 2 0 0 2 2 2 1 Nnf1 GOLGA2L5 PF15070.6 KEZ41562.1 - 0.0023 16.7 0.8 0.0028 16.4 0.8 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 YqjK PF13997.6 KEZ41562.1 - 0.014 15.6 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 YqjK-like protein LOH1CR12 PF10158.9 KEZ41562.1 - 0.024 14.7 0.7 0.087 12.8 0.4 1.9 1 1 1 2 2 2 0 Tumour suppressor protein CENP-F_leu_zip PF10473.9 KEZ41562.1 - 0.029 14.4 0.8 0.068 13.2 0.8 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 KEZ41562.1 - 0.058 13.6 1.2 0.096 12.9 0.4 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Snapin_Pallidin PF14712.6 KEZ41562.1 - 0.085 13.3 1.2 0.21 12.0 1.2 1.7 1 0 0 1 1 1 0 Snapin/Pallidin DUF4164 PF13747.6 KEZ41562.1 - 0.26 11.6 6.9 0.12 12.6 3.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.11 KEZ41562.1 - 0.32 9.8 5.5 0.13 11.1 3.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 KEZ41562.1 - 5.6 6.8 7.6 4.1 7.2 3.4 2.2 1 1 1 2 2 2 0 Septum formation initiator PH_9 PF15410.6 KEZ41563.1 - 6.2e-06 26.6 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KEZ41563.1 - 0.013 16.0 0.1 0.029 14.9 0.1 1.7 1 1 0 1 1 1 0 PH domain NTF2 PF02136.20 KEZ41564.1 - 9.4e-26 90.7 0.1 1.4e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KEZ41564.1 - 2e-08 33.9 0.1 4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KEZ41564.1 - 1.4 8.9 19.7 3.3 7.7 19.7 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CH PF00307.31 KEZ41565.1 - 4.1e-13 49.5 0.0 6.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF572 PF04502.13 KEZ41565.1 - 1.8 8.1 31.3 0.073 12.7 23.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) Zn_clus PF00172.18 KEZ41566.1 - 8.4e-05 22.6 13.6 0.0002 21.4 13.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GerD PF17898.1 KEZ41566.1 - 0.016 15.1 0.1 0.042 13.8 0.1 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain zf-C2H2 PF00096.26 KEZ41567.1 - 0.0045 17.4 4.1 0.032 14.7 0.2 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ41567.1 - 0.023 15.5 4.5 6.4 7.9 0.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger JTB PF05439.12 KEZ41568.1 - 0.3 11.1 1.1 19 5.3 0.1 2.4 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) L51_S25_CI-B8 PF05047.16 KEZ41569.1 - 4.8e-15 55.2 0.0 8.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 KEZ41570.1 - 5.5e-87 291.2 0.0 6.3e-87 291.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase U1snRNP70_N PF12220.8 KEZ41571.1 - 8.4e-26 90.4 5.3 1.9e-25 89.3 5.3 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KEZ41571.1 - 4.1e-18 65.0 0.0 2.1e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ41571.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Ribosomal_L10 PF00466.20 KEZ41572.1 - 3e-19 69.0 0.0 5.1e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KEZ41572.1 - 1.6e-11 44.0 0.0 3.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Fungal_trans PF04082.18 KEZ41572.1 - 7.7e-10 38.3 0.2 2.2e-09 36.7 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41572.1 - 1.7e-09 37.6 6.9 3.5e-09 36.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAPEG PF01124.18 KEZ41573.1 - 1.5e-13 50.8 1.2 1.8e-13 50.5 1.2 1.1 1 0 0 1 1 1 1 MAPEG family GH131_N PF18271.1 KEZ41574.1 - 1.3e-65 221.7 1.9 1.5e-65 221.5 1.9 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Na_H_Exchanger PF00999.21 KEZ41575.1 - 1.3e-71 241.4 42.1 1.6e-71 241.1 42.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HSA PF07529.13 KEZ41576.1 - 1.7e-13 50.7 0.1 1.7e-13 50.7 0.1 4.7 4 1 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 KEZ41576.1 - 2.2e-13 50.3 0.8 5.9e-13 48.9 0.8 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEZ41576.1 - 0.00017 21.7 0.9 0.00035 20.7 0.9 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cytochrom_B561 PF03188.16 KEZ41577.1 - 8e-05 22.8 4.6 8e-05 22.8 4.6 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 AA_permease_C PF13906.6 KEZ41577.1 - 0.028 14.5 1.2 0.028 14.5 1.2 1.8 2 0 0 2 2 2 0 C-terminus of AA_permease DUF4079 PF13301.6 KEZ41577.1 - 0.12 12.6 12.2 0.28 11.4 1.9 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF4079) NDUFA12 PF05071.16 KEZ41578.1 - 1.3e-11 45.1 0.3 1.3e-11 45.1 0.3 2.1 3 0 0 3 3 3 1 NADH ubiquinone oxidoreductase subunit NDUFA12 AMP-binding PF00501.28 KEZ41580.1 - 8.4e-10 37.8 0.0 1.2e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ41580.1 - 0.0007 20.5 0.0 0.0012 19.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GerPB PF10803.8 KEZ41580.1 - 0.014 15.5 0.5 0.039 14.1 0.5 1.8 1 0 0 1 1 1 0 Spore germination GerPB Fusion_gly PF00523.18 KEZ41580.1 - 0.15 10.3 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 SHS2_Rpb7-N PF03876.17 KEZ41580.1 - 0.15 12.4 0.0 3.4 8.1 0.0 2.9 3 0 0 3 3 3 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AtuA PF07287.11 KEZ41581.1 - 5.3e-122 406.9 0.0 7.1e-122 406.5 0.0 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Fungal_trans PF04082.18 KEZ41581.1 - 6.2e-12 45.1 0.3 1e-11 44.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.17 KEZ41582.1 - 1.2e-124 416.2 0.0 1.4e-124 416.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.18 KEZ41583.1 - 1.3e-26 93.2 0.3 2.1e-26 92.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41583.1 - 1.2e-06 28.5 9.5 2.7e-06 27.4 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMGL-like PF00682.19 KEZ41584.1 - 5.4e-45 154.0 0.0 7.6e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 KEZ41584.1 - 1.1e-39 136.3 0.0 1.7e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ41584.1 - 1.5e-30 106.9 0.0 2.4e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PdxJ PF03740.13 KEZ41584.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ MFS_1 PF07690.16 KEZ41585.1 - 1.1e-31 110.1 30.4 2.3e-30 105.7 32.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.22 KEZ41586.1 - 1.5e-149 498.4 0.0 1.7e-149 498.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ41586.1 - 0.11 11.9 0.0 5.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ADH_N PF08240.12 KEZ41587.1 - 8.2e-30 102.9 2.3 1.5e-29 102.0 2.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ41587.1 - 4.5e-16 59.0 0.2 7.5e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ41587.1 - 1.4e-06 28.0 0.1 2.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KEZ41587.1 - 2.8e-05 23.5 0.3 0.00038 19.8 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KEZ41587.1 - 6e-05 24.1 0.0 0.00015 22.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KEZ41587.1 - 0.18 11.7 0.3 0.18 11.7 0.3 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Isochorismatase PF00857.20 KEZ41588.1 - 2.9e-07 30.8 0.0 6.4e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family Hemerythrin PF01814.23 KEZ41589.1 - 5.1e-09 36.8 5.2 8.1e-09 36.2 5.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain eIF-3c_N PF05470.12 KEZ41590.1 - 7e-175 582.7 17.0 7e-175 582.7 17.0 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KEZ41590.1 - 2.9e-12 47.0 0.7 1.3e-11 44.9 0.0 2.6 3 0 0 3 3 3 1 PCI domain DUF3713 PF12506.8 KEZ41590.1 - 0.076 13.3 2.2 0.2 11.9 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) DUF2779 PF11074.8 KEZ41590.1 - 0.21 12.1 1.3 5.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function(DUF2779) Fe-S_biosyn PF01521.20 KEZ41591.1 - 3.1e-11 43.4 0.0 1.5e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis AAA_19 PF13245.6 KEZ41591.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ribosomal_L30_N PF08079.12 KEZ41592.1 - 3.6e-23 81.6 18.2 6.4e-23 80.8 18.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KEZ41592.1 - 2.2e-17 62.7 1.9 5.1e-17 61.5 1.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.11 KEZ41592.1 - 0.22 11.9 2.3 0.46 10.8 2.3 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus Ribosomal_S11 PF00411.19 KEZ41593.1 - 1.9e-46 157.0 1.6 2.3e-46 156.7 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 KEZ41593.1 - 0.075 12.3 0.2 0.096 12.0 0.2 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme CBM_25 PF03423.13 KEZ41593.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) SNF2_N PF00176.23 KEZ41594.1 - 4.9e-69 232.7 0.0 7.3e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ41594.1 - 7.3e-19 68.2 0.0 2.6e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ41594.1 - 1.2e-07 31.9 0.0 3.2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEZ41594.1 - 0.0064 15.7 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 KEZ41594.1 - 0.0093 15.2 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 LCD1 PF09798.9 KEZ41594.1 - 1.5 7.2 3.8 3.6 6.0 3.8 1.5 1 0 0 1 1 1 0 DNA damage checkpoint protein PHM7_cyt PF14703.6 KEZ41594.1 - 2.2 8.5 5.8 1.4 9.1 3.8 1.7 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF724 PF05266.14 KEZ41594.1 - 6.6 6.5 9.4 7.9 6.3 7.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Myb_DNA-bind_6 PF13921.6 KEZ41595.1 - 1.3e-13 51.0 0.2 2.1e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEZ41595.1 - 5.5e-13 48.9 0.1 6.6e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain MEF2_binding PF09047.10 KEZ41595.1 - 0.16 11.8 1.3 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 MEF2 binding RNA_pol_I_A49 PF06870.12 KEZ41596.1 - 3.8e-75 253.2 0.1 4.8e-75 252.8 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Pkinase PF00069.25 KEZ41597.1 - 4.6e-08 32.8 0.0 6.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KEZ41597.1 - 0.0018 17.6 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ41597.1 - 0.027 14.4 0.5 1.6 8.6 0.4 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ECH_1 PF00378.20 KEZ41598.1 - 3.5e-23 82.2 0.0 5e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ41598.1 - 3.5e-12 46.5 0.0 4.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 KEZ41599.1 - 5.6e-28 97.7 0.0 7.5e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41599.1 - 1.4e-19 70.6 0.0 1.8e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41599.1 - 2.1e-11 44.0 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KEZ41599.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Urb2 PF10441.9 KEZ41600.1 - 4.7e-58 196.5 0.0 4.7e-57 193.2 0.0 2.7 3 0 0 3 3 3 1 Urb2/Npa2 family FANCI_S3 PF14677.6 KEZ41600.1 - 0.0068 16.1 0.1 0.028 14.1 0.1 2.0 2 0 0 2 2 2 1 FANCI solenoid 3 DUF543 PF04418.12 KEZ41601.1 - 6.2e-30 103.0 0.0 6.9e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Pkinase PF00069.25 KEZ41602.1 - 2.9e-53 180.9 0.0 4.1e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41602.1 - 2.7e-25 89.1 0.0 4.3e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEZ41602.1 - 2.3e-06 27.1 0.0 6.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ41602.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FHA PF00498.26 KEZ41602.1 - 0.0057 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF3543 PF12063.8 KEZ41603.1 - 1.6e-93 312.7 0.1 2.4e-93 312.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KEZ41603.1 - 1.7e-60 204.6 0.0 4.2e-60 203.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41603.1 - 8.3e-42 143.3 0.0 1.5e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KEZ41603.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MIT PF04212.18 KEZ41603.1 - 0.28 11.3 2.1 3.5 7.8 0.1 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Aminotran_3 PF00202.21 KEZ41604.1 - 4.9e-119 397.6 0.0 5.7e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEZ41604.1 - 0.00044 19.5 0.0 0.00067 18.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEZ41604.1 - 0.0008 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.17 KEZ41605.1 - 3.6e-71 240.6 15.7 4.8e-71 240.2 15.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KEZ41605.1 - 0.002 18.3 4.3 0.048 13.9 4.2 2.8 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RhoGAP PF00620.27 KEZ41606.1 - 1.6e-37 128.6 0.0 2.8e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Nup188_C PF18378.1 KEZ41607.1 - 1.8e-153 510.8 0.3 1.8e-153 510.8 0.3 1.7 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KEZ41607.1 - 1.3e-47 162.3 0.0 7.1e-39 133.5 0.0 2.8 2 2 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.15 KEZ41608.1 - 3e-18 65.2 4.5 4.6e-18 64.6 4.5 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger IGPS PF00218.21 KEZ41609.1 - 6.1e-97 323.7 0.0 1.2e-96 322.8 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KEZ41609.1 - 1.7e-51 174.8 0.6 1.7e-46 158.5 0.1 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KEZ41609.1 - 7.2e-47 159.6 0.1 1.2e-45 155.6 0.0 2.6 3 0 0 3 3 3 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEZ41609.1 - 0.00017 21.4 0.2 0.00099 18.9 0.2 2.1 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KEZ41609.1 - 0.03 14.1 3.0 0.77 9.5 0.1 3.3 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 KEZ41609.1 - 0.031 13.7 0.4 2.1 7.8 0.0 3.2 4 0 0 4 4 4 0 Histidine biosynthesis protein FMN_dh PF01070.18 KEZ41609.1 - 0.053 12.6 0.3 0.82 8.6 0.1 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PTCB-BRCT PF12738.7 KEZ41610.1 - 5.9e-05 22.9 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KEZ41610.1 - 0.00014 22.1 0.0 0.0004 20.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAT PF03417.16 KEZ41610.1 - 0.054 13.2 0.1 0.12 12.0 0.1 1.5 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase BRCT_2 PF16589.5 KEZ41610.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain PAS_9 PF13426.7 KEZ41610.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 PAS domain Use1 PF09753.9 KEZ41611.1 - 8.4e-11 42.1 0.1 1e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 Membrane fusion protein Use1 Nucleo_P87 PF07267.11 KEZ41611.1 - 0.08 11.8 8.6 0.096 11.5 8.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 XRCC4 PF06632.12 KEZ41611.1 - 0.93 8.3 8.3 2.5 6.9 8.5 1.7 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SPX PF03105.19 KEZ41611.1 - 4.2 7.2 12.5 6.5 6.6 12.5 1.4 1 0 0 1 1 1 0 SPX domain cwf21 PF08312.12 KEZ41612.1 - 4.1e-16 58.9 14.8 4.1e-16 58.9 14.8 1.8 2 0 0 2 2 2 1 cwf21 domain DUF1129 PF06570.11 KEZ41612.1 - 0.055 12.9 0.3 0.072 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) HU-CCDC81_bac_2 PF18175.1 KEZ41612.1 - 1.2 9.1 4.5 4.7 7.1 0.3 2.5 2 1 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 D123 PF07065.14 KEZ41613.1 - 2.4e-113 378.4 0.0 2.7e-113 378.2 0.0 1.0 1 0 0 1 1 1 1 D123 DUF3716 PF12511.8 KEZ41615.1 - 1.8e-15 56.7 10.8 2.9e-15 56.1 10.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) AMP-binding PF00501.28 KEZ41615.1 - 0.021 13.4 0.2 0.045 12.3 0.2 1.5 1 0 0 1 1 1 0 AMP-binding enzyme Siva PF05458.12 KEZ41615.1 - 0.067 12.9 3.7 0.14 11.8 3.7 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) NGP1NT PF08153.12 KEZ41615.1 - 0.11 12.6 1.1 0.25 11.5 1.1 1.5 1 0 0 1 1 1 0 NGP1NT (NUC091) domain G-alpha PF00503.20 KEZ41616.1 - 3.4e-124 414.6 3.4 3.9e-124 414.4 3.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KEZ41616.1 - 3.3e-15 56.0 2.2 2.4e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KEZ41616.1 - 0.00013 21.7 0.0 0.00057 19.6 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KEZ41616.1 - 0.0019 17.6 3.2 0.072 12.4 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KEZ41616.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 KEZ41616.1 - 0.024 14.9 0.2 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KEZ41616.1 - 0.058 12.6 0.2 0.096 11.8 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.27 KEZ41616.1 - 0.085 12.4 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 KEZ41616.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain MMR_HSR1 PF01926.23 KEZ41616.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 KEZ41616.1 - 0.14 11.5 0.0 0.31 10.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1771 PF08590.10 KEZ41617.1 - 6.5e-24 84.1 8.8 1.1e-23 83.3 8.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KEZ41617.1 - 5.5e-12 45.9 1.3 8.6e-12 45.3 0.5 1.8 2 0 0 2 2 2 1 Smr domain RHH_4 PF13467.6 KEZ41617.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain KTI12 PF08433.10 KEZ41618.1 - 2.7e-67 227.1 0.0 3.9e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KEZ41618.1 - 0.0035 17.5 0.5 0.0089 16.2 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEZ41618.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEZ41618.1 - 0.053 14.1 1.6 0.32 11.6 1.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ41618.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 KEZ41618.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.29 KEZ41619.1 - 1.9e-98 326.0 0.0 1.1e-47 161.8 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ41619.1 - 1.3e-24 85.7 4.8 7e-14 51.4 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KEZ41619.1 - 3.1e-19 68.9 0.3 1.2e-18 67.0 0.3 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KEZ41619.1 - 1.8e-14 53.8 0.2 6.1e-06 26.1 0.0 3.7 5 1 0 5 5 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEZ41619.1 - 7.5e-14 52.2 0.0 3.1e-07 30.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEZ41619.1 - 2.7e-13 50.7 0.0 0.0002 21.8 0.0 4.4 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 KEZ41619.1 - 2.4e-12 47.2 0.0 3.4e-05 24.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KEZ41619.1 - 4.1e-12 46.3 0.3 3.6e-06 27.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ41619.1 - 1.8e-09 38.0 0.4 0.028 14.7 0.0 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KEZ41619.1 - 2.9e-09 36.6 0.9 0.0014 17.9 0.0 3.1 3 1 0 3 3 3 2 TIP49 P-loop domain CDC48_2 PF02933.17 KEZ41619.1 - 9.6e-09 34.9 0.4 5.4e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KEZ41619.1 - 1.4e-07 32.1 0.0 0.026 15.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 KEZ41619.1 - 2e-07 30.6 0.3 0.0063 15.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 KEZ41619.1 - 3.1e-07 30.3 0.2 5.1e-06 26.4 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KEZ41619.1 - 3.6e-07 30.1 0.0 0.02 14.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KEZ41619.1 - 5.4e-07 29.7 0.0 0.0076 16.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KEZ41619.1 - 6.4e-07 29.7 0.0 0.036 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.6 KEZ41619.1 - 1e-06 29.1 0.2 0.15 12.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain ATPase PF06745.13 KEZ41619.1 - 1.5e-06 27.8 0.4 0.26 10.6 0.0 3.6 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KEZ41619.1 - 1.8e-06 27.6 0.1 0.026 14.0 0.0 2.9 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KEZ41619.1 - 2e-06 27.5 3.7 0.2 11.2 0.0 4.5 3 2 2 5 5 5 2 AAA domain AAA_24 PF13479.6 KEZ41619.1 - 3.7e-06 26.8 0.0 0.082 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 KEZ41619.1 - 8.5e-06 25.1 0.0 0.051 12.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 KEZ41619.1 - 1.2e-05 24.6 0.0 0.023 13.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KEZ41619.1 - 2.1e-05 24.3 0.0 0.25 11.0 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 KEZ41619.1 - 3.5e-05 24.4 0.0 0.41 11.2 0.0 3.7 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 KEZ41619.1 - 3.8e-05 23.6 0.0 0.23 11.3 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein TsaE PF02367.17 KEZ41619.1 - 6.4e-05 23.0 0.0 0.39 10.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KEZ41619.1 - 0.00011 22.3 0.0 0.045 13.7 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 KEZ41619.1 - 0.00014 21.9 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 KEZ41619.1 - 0.00016 22.1 0.0 0.59 10.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 KEZ41619.1 - 0.00023 21.0 0.0 0.71 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KEZ41619.1 - 0.00024 20.6 0.3 0.69 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 KEZ41619.1 - 0.0003 20.6 0.2 0.86 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KEZ41619.1 - 0.00033 20.5 0.2 1.2 8.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 KEZ41619.1 - 0.00047 20.1 0.0 2.1 8.2 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KEZ41619.1 - 0.0019 17.5 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KEZ41619.1 - 0.0024 17.6 0.0 0.33 10.7 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KEZ41619.1 - 0.0026 17.0 0.0 1.1 8.3 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain Sigma54_activ_2 PF14532.6 KEZ41619.1 - 0.0033 17.5 0.0 0.56 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 KEZ41619.1 - 0.0037 17.6 3.0 3.7 7.9 0.1 3.9 3 2 1 4 4 3 0 AAA domain NTPase_1 PF03266.15 KEZ41619.1 - 0.007 16.3 0.4 2.5 8.0 0.0 3.7 4 0 0 4 4 3 1 NTPase UFD1 PF03152.14 KEZ41619.1 - 0.011 15.2 0.0 0.12 11.8 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 IPT PF01745.16 KEZ41619.1 - 0.012 15.0 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 KEZ41619.1 - 0.022 14.0 0.2 7.8 5.7 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin KAP_NTPase PF07693.14 KEZ41619.1 - 0.026 13.8 0.5 1.1 8.4 0.0 3.3 2 2 1 4 4 4 0 KAP family P-loop domain AAA_6 PF12774.7 KEZ41619.1 - 0.047 12.7 0.1 7.6 5.4 0.0 2.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 KEZ41619.1 - 0.055 13.2 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 KEZ41619.1 - 0.067 12.1 0.1 8 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Zot PF05707.12 KEZ41619.1 - 0.077 12.6 0.0 3 7.5 0.0 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin2 PF13189.6 KEZ41619.1 - 0.077 13.1 0.6 3.3 7.8 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase-like family EnY2 PF10163.9 KEZ41620.1 - 0.071 13.5 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Transcription factor e(y)2 ABC_tran PF00005.27 KEZ41621.1 - 4.5e-31 108.2 0.0 9.6e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KEZ41621.1 - 2.5e-28 99.5 9.7 2.5e-28 99.5 9.7 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KEZ41621.1 - 4.4e-05 23.0 0.0 0.00019 21.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KEZ41621.1 - 0.0097 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 KEZ41621.1 - 0.12 12.6 0.1 1.7 8.9 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KEZ41621.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRAM_LAG1_CLN8 PF03798.16 KEZ41622.1 - 1.2e-36 126.3 16.1 2.1e-36 125.5 16.1 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KEZ41622.1 - 7.2e-26 89.6 0.3 1.7e-25 88.5 0.3 1.7 1 0 0 1 1 1 1 TRAM1-like protein Glyco_hydro_3_C PF01915.22 KEZ41623.1 - 9.1e-36 123.7 0.0 1.5e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ41623.1 - 8.1e-33 114.1 0.0 1.5e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ41623.1 - 1.1e-06 28.6 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_GDSL_2 PF13472.6 KEZ41625.1 - 4.4e-16 59.8 0.7 6.2e-16 59.3 0.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ41625.1 - 1e-09 38.6 0.0 1.1e-08 35.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_3_C PF01915.22 KEZ41625.1 - 0.018 15.0 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Lipase_GDSL_2 PF13472.6 KEZ41626.1 - 4.2e-13 50.1 1.1 6.8e-12 46.2 1.1 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family fn3 PF00041.21 KEZ41626.1 - 1.9e-11 44.1 5.6 8.4e-08 32.5 0.2 4.0 3 1 1 4 4 4 2 Fibronectin type III domain Lipase_GDSL PF00657.22 KEZ41626.1 - 0.028 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4992 PF16383.5 KEZ41626.1 - 0.069 12.7 0.7 25 4.4 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function F-box-like PF12937.7 KEZ41627.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KEZ41627.1 - 0.0071 16.1 1.4 0.012 15.3 0.4 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KEZ41627.1 - 0.01 16.3 0.1 0.025 15.0 0.1 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Questin_oxidase PF14027.6 KEZ41628.1 - 3.4e-66 224.1 0.1 4.3e-66 223.8 0.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like FAD_binding_3 PF01494.19 KEZ41629.1 - 1.6e-37 129.6 0.0 1.8e-22 80.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Fungal_trans PF04082.18 KEZ41630.1 - 6e-11 41.9 0.0 9.5e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 KEZ41631.1 - 1.6e-61 208.8 0.1 2e-30 106.1 0.0 3.0 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ41631.1 - 0.00038 20.4 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SQS_PSY PF00494.19 KEZ41632.1 - 5.8e-36 124.3 0.0 8.2e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CFEM PF05730.11 KEZ41633.1 - 1.7e-12 47.2 15.6 3.2e-12 46.4 15.6 1.4 1 0 0 1 1 1 1 CFEM domain NACHT PF05729.12 KEZ41634.1 - 2.7e-11 43.7 0.0 6.3e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ41634.1 - 2.2e-05 24.7 0.0 0.00011 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain WSC PF01822.19 KEZ41634.1 - 4.4e-05 23.6 8.0 0.00011 22.3 8.0 1.7 1 0 0 1 1 1 1 WSC domain AAA_16 PF13191.6 KEZ41634.1 - 7.7e-05 23.1 0.4 0.0003 21.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain SesA PF17107.5 KEZ41634.1 - 0.00025 21.2 0.1 0.0007 19.8 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA PF00004.29 KEZ41634.1 - 0.00026 21.4 0.0 0.0014 19.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KEZ41634.1 - 0.0012 18.8 0.1 0.0038 17.2 0.0 1.9 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KEZ41634.1 - 0.013 16.1 0.1 0.15 12.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KEZ41634.1 - 0.02 15.4 0.0 0.076 13.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KEZ41634.1 - 0.033 13.9 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ41634.1 - 0.037 13.9 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase KAP_NTPase PF07693.14 KEZ41634.1 - 0.046 13.0 4.1 0.75 9.0 0.0 2.8 3 0 0 3 3 3 0 KAP family P-loop domain RNA_helicase PF00910.22 KEZ41634.1 - 0.051 14.0 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase RHH_6 PF16762.5 KEZ41634.1 - 0.084 13.5 0.1 2 9.1 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain AAA_24 PF13479.6 KEZ41634.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TraC_F_IV PF11130.8 KEZ41634.1 - 0.15 11.7 1.0 0.32 10.5 1.0 1.5 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer AAA_33 PF13671.6 KEZ41634.1 - 0.24 11.6 4.2 0.71 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Vac14_Fig4_bd PF11916.8 KEZ41635.1 - 0.17 11.5 0.2 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding DUF1180 PF06679.12 KEZ41635.1 - 0.44 10.9 2.4 0.92 9.9 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) adh_short_C2 PF13561.6 KEZ41636.1 - 3.4e-48 164.3 2.6 4e-48 164.0 2.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ41636.1 - 2.8e-43 147.7 1.0 3.5e-43 147.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ41636.1 - 8e-11 42.2 1.0 1.1e-10 41.7 1.0 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KEZ41636.1 - 0.031 14.2 1.2 0.036 14.0 0.2 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus PSK_trans_fac PF07704.11 KEZ41636.1 - 0.035 14.9 0.5 1.9 9.3 0.1 2.7 1 1 1 2 2 2 0 Rv0623-like transcription factor DUF1598 PF07643.11 KEZ41636.1 - 0.078 13.2 0.2 1.8 8.9 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1598) adh_short PF00106.25 KEZ41637.1 - 1.4e-09 37.7 0.1 2.5e-09 36.9 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41637.1 - 7.4e-09 35.5 0.1 9.8e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 KEZ41637.1 - 0.0056 17.2 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEZ41637.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ41637.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KEZ41637.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_2 PF00891.18 KEZ41639.1 - 2.9e-23 82.3 0.0 1.6e-22 79.9 0.0 1.9 1 1 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KEZ41639.1 - 0.00071 20.2 0.0 0.0014 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41639.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KEZ41639.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase D123 PF07065.14 KEZ41639.1 - 0.054 12.6 0.2 0.37 9.9 0.0 2.3 2 1 1 3 3 3 0 D123 Methyltransf_12 PF08242.12 KEZ41639.1 - 0.068 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.11 KEZ41640.1 - 5.5e-26 91.7 0.0 8.6e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KEZ41641.1 - 6.3e-09 35.3 0.3 9.5e-09 34.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 KEZ41642.1 - 4.8e-24 85.4 0.7 8.2e-24 84.6 0.7 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.11 KEZ41642.1 - 4e-23 82.4 0.0 7.9e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Say1_Mug180 PF10340.9 KEZ41642.1 - 2e-13 50.0 0.0 3.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KEZ41642.1 - 0.0043 16.5 0.0 0.042 13.3 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Con-6 PF10346.9 KEZ41643.1 - 4.6e-30 103.3 6.5 1.1e-14 54.2 0.1 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 KEZ41643.1 - 0.028 14.3 0.1 1.9 8.3 0.0 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein ATP-synt_DE PF00401.20 KEZ41643.1 - 0.11 12.8 4.5 2.7 8.3 0.2 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NACHT PF05729.12 KEZ41644.1 - 0.076 12.9 0.0 0.28 11.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain CSN5_C PF18323.1 KEZ41644.1 - 0.08 13.9 0.3 3.6 8.6 0.0 2.8 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain ATG16 PF08614.11 KEZ41644.1 - 0.33 11.2 4.7 0.63 10.2 4.7 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 KEZ41644.1 - 0.96 10.0 3.4 23 5.6 0.1 3.6 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CorA PF01544.18 KEZ41647.1 - 2.4e-14 53.3 0.5 9e-14 51.5 0.0 2.2 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein SKG6 PF08693.10 KEZ41647.1 - 0.81 9.1 2.9 1.6 8.2 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Dynamin_N PF00350.23 KEZ41649.1 - 5.8e-35 120.8 0.0 1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEZ41649.1 - 3.3e-23 82.3 0.0 5.3e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KEZ41649.1 - 5e-05 23.4 0.0 0.00021 21.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KEZ41649.1 - 0.00033 20.7 0.4 0.0019 18.3 0.2 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_15 PF13175.6 KEZ41649.1 - 0.041 13.6 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KEZ41649.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SOG2 PF10428.9 KEZ41650.1 - 0.49 9.5 3.7 0.47 9.6 3.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF515 PF04415.12 KEZ41650.1 - 4.2 5.7 6.8 6.7 5.0 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Podoplanin PF05808.11 KEZ41651.1 - 0.0083 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Podoplanin Gram_pos_anchor PF00746.21 KEZ41651.1 - 0.019 14.9 2.2 0.04 13.8 2.2 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DAP10 PF07213.11 KEZ41651.1 - 0.048 13.6 0.3 0.1 12.6 0.3 1.5 1 0 0 1 1 1 0 DAP10 membrane protein VSP PF03302.13 KEZ41651.1 - 0.061 12.2 0.5 0.093 11.6 0.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Syndecan PF01034.20 KEZ41651.1 - 0.28 11.1 0.4 0.51 10.3 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain Aldose_epim PF01263.20 KEZ41652.1 - 1.1e-48 166.1 0.3 1.5e-48 165.7 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2064 PF09837.9 KEZ41652.1 - 0.14 11.9 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) WSC PF01822.19 KEZ41653.1 - 0.0023 18.1 0.1 0.0023 18.1 0.1 3.2 3 2 0 3 3 3 1 WSC domain Collagen PF01391.18 KEZ41654.1 - 0.00057 19.6 24.5 0.00099 18.8 24.5 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF2448 PF10476.9 KEZ41654.1 - 0.0022 17.9 1.0 0.0038 17.1 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) CCSAP PF15748.5 KEZ41654.1 - 0.01 16.0 11.4 0.014 15.6 11.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SPX PF03105.19 KEZ41654.1 - 0.025 14.5 9.7 0.027 14.4 9.7 1.1 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 KEZ41654.1 - 0.03 13.1 8.9 0.04 12.7 8.9 1.2 1 0 0 1 1 1 0 Presenilin PNISR PF15996.5 KEZ41654.1 - 0.11 12.8 7.6 0.15 12.4 7.6 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SprA-related PF12118.8 KEZ41654.1 - 0.45 9.6 13.6 0.56 9.3 13.6 1.1 1 0 0 1 1 1 0 SprA-related family Corona_nucleoca PF00937.18 KEZ41654.1 - 0.46 9.5 9.0 0.66 9.0 9.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PA26 PF04636.13 KEZ41654.1 - 0.57 9.0 4.6 0.68 8.8 4.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) EVI2A PF05399.11 KEZ41654.1 - 1 8.9 10.7 1.4 8.4 10.7 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF913 PF06025.12 KEZ41654.1 - 2.1 7.2 6.8 3 6.7 6.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 KEZ41654.1 - 3 6.5 9.4 3.9 6.2 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 KEZ41654.1 - 3.1 5.8 10.0 4 5.4 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 KEZ41654.1 - 5.7 5.6 10.7 6.9 5.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 KEZ41654.1 - 8.5 4.9 6.9 10 4.7 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.6 KEZ41654.1 - 9.4 4.9 10.4 13 4.4 10.4 1.1 1 0 0 1 1 1 0 Raftlin SOG2 PF10428.9 KEZ41654.1 - 9.4 5.3 16.2 12 5.0 16.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Methyltransf_23 PF13489.6 KEZ41655.1 - 1.2e-19 70.7 0.1 2.1e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41655.1 - 1.9e-10 41.3 0.0 1.9e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41655.1 - 1.7e-08 34.4 0.1 3.8e-07 30.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41655.1 - 9.5e-07 29.4 0.0 3.2e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ41655.1 - 4.7e-05 22.9 0.2 0.00039 19.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 KEZ41655.1 - 7.2e-05 23.5 0.0 0.00035 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ41655.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KEZ41655.1 - 0.0019 17.6 0.0 0.0057 16.0 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KEZ41655.1 - 0.0028 17.8 0.0 0.0041 17.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KEZ41655.1 - 0.0031 16.9 0.0 0.028 13.7 0.0 2.2 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Birna_VP4 PF01768.16 KEZ41655.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein Methyltransf_2 PF00891.18 KEZ41655.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain p450 PF00067.22 KEZ41656.1 - 1.2e-45 156.2 0.0 1.6e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.11 KEZ41658.1 - 2.3e-24 86.3 0.0 4.2e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KEZ41658.1 - 0.00025 20.4 0.3 0.00039 19.8 0.3 1.2 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 KEZ41659.1 - 3.8e-22 78.7 43.1 4.4e-20 71.9 26.2 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ41659.1 - 2.5e-07 29.5 19.9 7.7e-07 27.9 19.9 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mem_trans PF03547.18 KEZ41660.1 - 8.7e-17 60.6 9.5 2.2e-10 39.5 4.1 2.0 2 0 0 2 2 2 2 Membrane transport protein PhoLip_ATPase_C PF16212.5 KEZ41660.1 - 4 7.1 8.7 22 4.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal zf-met PF12874.7 KEZ41661.1 - 1.5e-36 123.7 29.3 4.6e-06 26.8 0.3 7.2 7 0 0 7 7 7 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KEZ41661.1 - 2.3e-31 107.4 37.9 1.3e-05 25.3 0.6 7.3 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KEZ41661.1 - 4.6e-23 80.7 13.2 0.0031 17.5 0.1 7.2 6 1 1 7 7 7 6 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEZ41661.1 - 6.3e-22 77.8 36.6 0.0047 17.2 0.3 7.0 1 1 6 7 7 7 7 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KEZ41661.1 - 1.4e-19 69.0 13.4 0.1 13.5 0.0 7.4 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ41661.1 - 9.5e-18 63.6 24.4 0.024 15.1 0.1 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KEZ41661.1 - 1.4e-11 44.0 29.3 0.29 11.1 0.1 7.5 8 0 0 8 8 7 7 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 KEZ41661.1 - 3.2e-11 42.8 0.0 2.1 8.2 0.0 7.0 7 0 0 7 7 7 1 zinc-finger C2H2-type zf_UBZ PF18439.1 KEZ41661.1 - 1.2e-10 40.8 32.4 0.51 10.0 0.1 7.2 7 0 0 7 7 7 6 Ubiquitin-Binding Zinc Finger zf-3CxxC PF13695.6 KEZ41661.1 - 2.9e-07 30.9 25.7 7.5 7.1 0.3 7.0 1 1 6 7 7 7 0 Zinc-binding domain LIM PF00412.22 KEZ41661.1 - 1.3e-06 28.5 30.7 0.15 12.3 1.8 5.1 1 1 5 6 6 6 6 LIM domain zf-DBF PF07535.12 KEZ41661.1 - 5.4e-06 26.4 33.2 0.97 9.6 0.2 7.3 7 0 0 7 7 7 3 DBF zinc finger DUF2256 PF10013.9 KEZ41661.1 - 0.00013 22.0 17.5 27 5.0 0.1 7.1 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc-ribbons_6 PF07191.12 KEZ41661.1 - 0.00019 21.3 29.1 2.8 8.0 3.2 6.4 1 1 5 6 6 6 4 zinc-ribbons zf-AN1 PF01428.16 KEZ41661.1 - 0.0015 18.7 26.5 5 7.4 0.9 7.3 6 1 1 7 7 7 1 AN1-like Zinc finger Sgf11 PF08209.11 KEZ41661.1 - 0.002 17.7 19.5 7.4 6.2 0.1 6.9 7 0 0 7 7 7 0 Sgf11 (transcriptional regulation protein) RNA_POL_M_15KD PF02150.16 KEZ41661.1 - 0.0027 17.6 22.1 6.1 6.8 0.1 7.0 7 0 0 7 7 7 0 RNA polymerases M/15 Kd subunit C1_2 PF03107.16 KEZ41661.1 - 0.0029 17.9 20.9 21 5.5 0.2 6.9 7 0 0 7 7 7 0 C1 domain Zn-ribbon_8 PF09723.10 KEZ41661.1 - 0.0029 17.7 38.3 2.1 8.6 5.4 6.9 5 2 2 7 7 7 3 Zinc ribbon domain HypA PF01155.19 KEZ41661.1 - 0.01 15.8 21.8 0.83 9.7 0.7 4.3 1 1 3 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0240 PF06784.11 KEZ41661.1 - 0.011 15.8 0.6 13 5.8 0.0 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0240) HNH_5 PF14279.6 KEZ41661.1 - 0.037 13.9 30.9 4.2 7.3 0.3 7.0 6 1 0 6 6 6 0 HNH endonuclease zf-3CxxC_2 PF17180.4 KEZ41661.1 - 0.039 14.7 31.5 9.7 7.0 0.1 6.9 2 1 2 5 5 5 0 Zinc-binding domain Herpes_UL52 PF03121.15 KEZ41661.1 - 0.049 13.6 20.4 10 6.1 0.1 6.7 1 1 6 7 7 7 0 Herpesviridae UL52/UL70 DNA primase Prok-RING_1 PF14446.6 KEZ41661.1 - 0.06 13.3 21.7 12 5.9 0.0 7.0 7 0 0 7 7 7 0 Prokaryotic RING finger family 1 HNH PF01844.23 KEZ41661.1 - 0.069 13.3 25.3 32 4.8 0.1 7.1 7 0 0 7 7 7 0 HNH endonuclease zf-H2C2_2 PF13465.6 KEZ41661.1 - 0.13 12.8 24.8 33 5.2 0.2 7.5 7 0 0 7 7 7 0 Zinc-finger double domain DUF3517 PF12030.8 KEZ41661.1 - 0.2 10.6 1.0 36 3.1 0.1 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF3517) zf-DNA_Pol PF08996.10 KEZ41661.1 - 0.45 10.2 21.9 1.7 8.3 1.5 4.0 1 1 3 4 4 4 0 DNA Polymerase alpha zinc finger PLATZ PF04640.14 KEZ41661.1 - 0.47 11.1 25.2 16 6.2 0.5 6.4 1 1 6 7 7 7 0 PLATZ transcription factor Rad50_zn_hook PF04423.14 KEZ41661.1 - 0.53 10.2 26.9 3 7.7 0.2 6.8 7 0 0 7 7 7 0 Rad50 zinc hook motif PhnA_Zn_Ribbon PF08274.12 KEZ41661.1 - 2 8.5 20.3 36 4.4 1.0 6.7 6 1 1 7 7 7 0 PhnA Zinc-Ribbon Arc_trans_TRASH PF08394.10 KEZ41661.1 - 2.4 8.6 28.2 46 4.5 0.1 7.0 7 0 0 7 7 7 0 Archaeal TRASH domain zf-C2H2_9 PF16293.5 KEZ41661.1 - 7 6.6 18.4 31 4.5 0.0 6.3 7 0 0 7 7 7 0 C2H2 type zinc-finger (1 copy) Actin_micro PF17003.5 KEZ41661.1 - 7.8 5.6 33.8 21 4.2 2.6 6.4 1 1 3 4 4 3 0 Putative actin-like family Ribonuc_L-PSP PF01042.21 KEZ41662.1 - 4.1e-09 36.5 0.0 6.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP MIG-14_Wnt-bd PF06664.12 KEZ41662.1 - 0.029 13.6 6.3 1.2 8.3 0.5 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Zn_clus PF00172.18 KEZ41663.1 - 0.021 14.9 5.3 0.037 14.1 5.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 KEZ41664.1 - 1.7e-66 223.8 15.9 2.5e-66 223.3 15.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 KEZ41665.1 - 0.0001 21.2 1.7 0.00013 20.9 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid_C PF17390.2 KEZ41666.1 - 5.2e-11 42.2 0.1 1.5e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KEZ41666.1 - 8.8e-05 21.9 0.0 0.0049 16.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1080 PF06439.11 KEZ41666.1 - 0.0009 19.4 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Laminin_G_2 PF02210.24 KEZ41666.1 - 0.1 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain ChiW_Ig_like PF18683.1 KEZ41666.1 - 0.12 12.6 0.1 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 Chitinase W immunoglobulin-like domain DUF908 PF06012.12 KEZ41667.1 - 2.2 7.6 5.8 2.8 7.2 5.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MHYT PF03707.16 KEZ41668.1 - 1.4e-16 60.4 24.9 1.7e-07 31.2 4.2 4.9 4 1 0 4 4 4 4 Bacterial signalling protein N terminal repeat DUF2177 PF09945.9 KEZ41668.1 - 0.056 13.5 4.1 0.096 12.8 0.1 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2177) Saf_2TM PF18303.1 KEZ41668.1 - 6.1 6.4 12.0 0.54 9.8 2.8 2.6 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain MFS_1 PF07690.16 KEZ41669.1 - 2.4e-28 99.1 12.6 4.3e-28 98.3 10.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ41669.1 - 0.0002 20.3 0.4 0.00042 19.3 0.4 1.6 1 0 0 1 1 1 1 MFS_1 like family TauD PF02668.16 KEZ41670.1 - 3.7e-63 213.9 0.2 5.4e-63 213.3 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3085 PF11284.8 KEZ41671.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) Pectate_lyase_3 PF12708.7 KEZ41672.1 - 1.9e-62 210.9 12.1 2.8e-55 187.5 5.8 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein DNase_NucA_NucB PF14040.6 KEZ41672.1 - 0.00034 21.0 1.1 0.0063 16.9 0.0 2.8 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB End_N_terminal PF12218.8 KEZ41672.1 - 0.0092 15.6 0.5 0.041 13.6 0.1 2.2 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase DUF917 PF06032.12 KEZ41674.1 - 4.9e-120 400.5 0.0 8.7e-120 399.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KEZ41674.1 - 3.8e-28 98.4 2.1 8.1e-26 90.8 0.3 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KEZ41674.1 - 2e-27 96.2 4.7 3.3e-25 88.9 2.1 2.8 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 KEZ41674.1 - 0.0029 16.3 0.6 0.49 8.9 0.1 2.6 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 KEZ41674.1 - 0.0081 15.7 2.5 0.017 14.6 0.1 2.6 4 0 0 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.13 KEZ41674.1 - 0.011 14.6 0.7 0.023 13.5 0.7 1.5 1 0 0 1 1 1 0 MreB/Mbl protein ROK PF00480.20 KEZ41674.1 - 0.015 14.8 0.1 0.058 12.9 0.1 2.0 1 0 0 1 1 1 0 ROK family StbA PF06406.11 KEZ41674.1 - 0.045 13.0 0.1 5.2 6.2 0.1 3.0 3 0 0 3 3 3 0 StbA protein FtsA PF14450.6 KEZ41674.1 - 0.2 12.1 10.4 2.7 8.4 0.1 3.9 2 1 0 2 2 2 0 Cell division protein FtsA Transp_cyt_pur PF02133.15 KEZ41675.1 - 2.5e-92 310.0 32.1 2.9e-92 309.7 32.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Thioredoxin PF00085.20 KEZ41676.1 - 5.2e-16 58.5 0.0 6.4e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KEZ41676.1 - 5.1e-05 23.0 0.1 0.026 14.2 0.2 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_2 PF13098.6 KEZ41676.1 - 0.0021 18.5 0.4 0.009 16.5 0.4 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KEZ41676.1 - 0.0028 17.6 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KEZ41676.1 - 0.019 15.2 0.1 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KEZ41676.1 - 0.042 13.9 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Mononeg_RNA_pol PF00946.19 KEZ41676.1 - 0.045 11.4 0.0 0.053 11.2 0.0 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase DSBA PF01323.20 KEZ41676.1 - 0.21 11.3 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain APH PF01636.23 KEZ41677.1 - 0.0014 18.6 0.4 0.13 12.2 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WD40 PF00400.32 KEZ41678.1 - 6.4e-13 49.0 17.2 2e-06 28.4 0.3 8.2 8 1 1 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41678.1 - 5.3e-10 39.5 0.3 1.4 9.3 0.0 7.1 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEZ41678.1 - 1.4e-07 31.5 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ41678.1 - 4.3e-07 30.5 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 KEZ41678.1 - 0.00013 20.8 3.3 0.23 10.1 0.1 4.0 2 2 2 4 4 4 1 Nucleoporin Nup120/160 AAA_22 PF13401.6 KEZ41678.1 - 0.00028 21.2 0.0 0.00078 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ41678.1 - 0.0088 15.8 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ41678.1 - 0.069 13.7 0.2 0.23 12.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEZ41678.1 - 0.18 10.9 0.0 0.5 9.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Defensin_2 PF01097.18 KEZ41680.1 - 6.4e-08 32.4 5.5 9.2e-08 31.9 5.5 1.2 1 0 0 1 1 1 1 Arthropod defensin Toxin_38 PF14866.6 KEZ41680.1 - 0.00043 20.5 3.3 0.00065 20.0 3.3 1.2 1 0 0 1 1 1 1 Potassium channel toxin Gamma-thionin PF00304.20 KEZ41680.1 - 0.08 13.2 2.8 0.12 12.7 2.8 1.2 1 0 0 1 1 1 0 Gamma-thionin family MFS_1 PF07690.16 KEZ41681.1 - 7.8e-33 113.8 28.8 1.6e-32 112.8 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ41681.1 - 8.6e-18 64.4 1.3 8.6e-18 64.4 1.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ41681.1 - 1.8e-06 26.7 5.7 1.8e-06 26.7 5.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Vma12 PF11712.8 KEZ41681.1 - 1 9.4 5.1 3.5 7.7 0.2 2.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Fungal_trans PF04082.18 KEZ41682.1 - 4.1e-18 65.4 0.1 8.4e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41682.1 - 8.6e-08 32.2 9.7 1.8e-07 31.1 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps39_2 PF10367.9 KEZ41682.1 - 0.1 13.0 0.9 0.27 11.7 0.9 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Methyltransf_25 PF13649.6 KEZ41683.1 - 3.8e-10 40.3 0.0 1.3e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41683.1 - 2e-08 34.8 0.0 7e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41683.1 - 2.2e-07 31.4 0.0 5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ41683.1 - 2.6e-07 30.6 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41683.1 - 5e-06 26.4 0.0 8.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ41683.1 - 0.046 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KEZ41683.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FAD_binding_3 PF01494.19 KEZ41684.1 - 2e-61 208.2 0.2 1.8e-23 83.4 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain Phe_hydrox_dim PF07976.12 KEZ41684.1 - 1.1e-56 191.4 0.0 4e-56 189.6 0.0 1.9 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KEZ41684.1 - 0.0016 17.3 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KEZ41684.1 - 0.0017 17.7 0.1 0.083 12.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ41684.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KEZ41684.1 - 0.0049 17.4 0.1 0.13 12.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ41684.1 - 0.0098 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KEZ41684.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEZ41684.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ41684.1 - 0.095 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ41684.1 - 0.16 11.5 0.0 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 KEZ41685.1 - 0.00091 18.3 0.3 0.0016 17.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KEZ41686.1 - 8.6e-47 159.6 0.0 1.2e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ41686.1 - 2.7e-24 86.3 0.5 7.5e-22 78.3 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MM_CoA_mutase PF01642.22 KEZ41686.1 - 0.014 14.0 0.1 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase Peptidase_S49 PF01343.18 KEZ41686.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 Acyl-CoA_dh_1 PF00441.24 KEZ41687.1 - 3.9e-30 105.0 1.5 5.5e-30 104.6 1.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KEZ41687.1 - 1.3e-25 90.2 0.0 3e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ41687.1 - 1.6e-21 76.3 0.2 2.5e-21 75.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AMP-binding PF00501.28 KEZ41688.1 - 7e-61 206.1 0.6 3.7e-47 160.9 0.2 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ41688.1 - 3.6e-09 37.5 0.0 1.4e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TLP1_add_C PF18313.1 KEZ41689.1 - 1.1e-18 66.9 0.0 2.4e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain NYD-SP28 PF14772.6 KEZ41690.1 - 0.027 14.5 0.8 0.027 14.5 0.8 2.7 2 1 1 3 3 3 0 Sperm tail PGAP1 PF07819.13 KEZ41690.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein BLOC1S3 PF15753.5 KEZ41690.1 - 0.15 12.2 2.5 11 6.1 0.0 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF3089 PF11288.8 KEZ41690.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Helo_like_N PF17111.5 KEZ41690.1 - 1.4 8.2 6.4 9 5.6 0.1 2.6 2 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins COesterase PF00135.28 KEZ41691.1 - 9.5e-34 117.1 0.1 5.1e-23 81.7 0.7 3.3 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ41691.1 - 0.0018 18.1 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold HgmA PF04209.13 KEZ41692.1 - 8.4e-138 459.6 0.0 9.8e-138 459.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Sugar_tr PF00083.24 KEZ41693.1 - 2e-73 247.8 25.1 2.3e-73 247.6 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41693.1 - 1.7e-13 50.3 42.8 2.7e-12 46.3 17.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEZ41693.1 - 2.7 6.2 20.6 0.35 9.1 3.0 3.7 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 KEZ41694.1 - 2.1e-46 158.4 0.0 1.8e-28 99.3 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ41694.1 - 0.00032 21.6 0.0 0.00061 20.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.19 KEZ41695.1 - 2.3e-22 79.7 0.0 4.1e-22 78.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ41695.1 - 2e-09 37.5 7.2 2.5e-07 30.6 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ41695.1 - 2.9e-06 26.8 0.7 0.014 14.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ41695.1 - 0.0001 21.3 1.3 0.054 12.3 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KEZ41695.1 - 0.00012 21.4 3.2 0.00019 20.6 2.7 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ41695.1 - 0.00029 21.0 0.5 0.00095 19.4 0.5 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ41695.1 - 0.0012 18.0 2.0 0.015 14.4 2.0 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KEZ41695.1 - 0.0025 18.4 0.6 1.1 9.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ41695.1 - 0.005 15.6 2.4 0.43 9.2 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ41695.1 - 0.037 13.3 1.0 0.33 10.2 1.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ41695.1 - 0.047 13.0 0.9 9.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KEZ41695.1 - 0.23 10.5 1.6 0.39 9.8 1.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 KEZ41695.1 - 0.24 10.4 0.0 0.78 8.7 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.7 KEZ41695.1 - 0.3 10.4 2.0 0.55 9.5 2.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HgmA PF04209.13 KEZ41696.1 - 3.4e-133 444.5 0.0 4.1e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Thiolase_N PF00108.23 KEZ41697.1 - 4.6e-54 183.5 0.0 8.2e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ41697.1 - 4.2e-45 152.4 0.2 8.7e-45 151.3 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 KEZ41697.1 - 4.3e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KEZ41697.1 - 0.0014 18.3 0.3 0.0067 16.0 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KEZ41697.1 - 0.002 17.9 0.3 0.36 10.7 0.1 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III OpcA PF07239.11 KEZ41700.1 - 0.085 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein OpcA DUF543 PF04418.12 KEZ41700.1 - 0.21 11.6 1.4 0.36 10.9 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Git3 PF11710.8 KEZ41702.1 - 3.9e-16 59.4 5.7 1.2e-15 57.8 5.7 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KEZ41702.1 - 3e-06 26.8 0.1 4e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KEZ41702.1 - 1.9e-05 24.6 0.1 4.4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Gpr1_Fun34_YaaH PF01184.19 KEZ41703.1 - 2.2e-27 96.0 15.8 3e-27 95.6 15.8 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FixS PF03597.15 KEZ41703.1 - 3.8 7.3 7.5 1.2 8.9 3.9 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type GFA PF04828.14 KEZ41704.1 - 1e-23 83.5 0.1 1.5e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 KEZ41704.1 - 0.042 13.7 1.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.9 KEZ41704.1 - 0.042 13.9 3.0 0.069 13.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.10 KEZ41704.1 - 0.099 12.4 0.0 0.099 12.4 0.0 2.4 3 0 0 3 3 3 0 A2L zinc ribbon domain MqsA_antitoxin PF15731.5 KEZ41704.1 - 0.14 12.3 1.4 1.6 8.9 0.0 2.1 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA MFS_1 PF07690.16 KEZ41705.1 - 2.6e-26 92.4 28.3 3.9e-26 91.8 28.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KEZ41705.1 - 1.5e-11 43.8 6.1 1.8e-10 40.2 6.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41705.1 - 0.00013 22.0 3.6 0.00024 21.2 3.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 KEZ41706.1 - 3.2e-16 60.0 0.0 6.4e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ41706.1 - 2.2e-05 24.7 2.2 0.048 13.9 0.1 2.8 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 KEZ41706.1 - 6.5e-05 23.4 0.2 0.00032 21.1 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KEZ41706.1 - 0.0041 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KEZ41706.1 - 0.015 15.0 0.0 0.1 12.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 KEZ41706.1 - 0.031 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KEZ41706.1 - 0.046 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Erf4 PF10256.9 KEZ41708.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family PEP-CTERM PF07589.11 KEZ41708.1 - 1 9.5 4.5 1.2 9.3 1.5 2.4 2 0 0 2 2 2 0 PEP-CTERM motif Pkinase PF00069.25 KEZ41709.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.18 KEZ41710.1 - 7.3e-10 38.3 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_binding PF02629.19 KEZ41711.1 - 5.4e-16 59.1 1.0 2.7e-15 56.8 0.1 2.4 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KEZ41711.1 - 1.8e-15 57.1 0.2 1.8e-15 57.1 0.2 1.9 3 0 0 3 3 3 1 CoA-ligase Succ_CoA_lig PF13607.6 KEZ41711.1 - 5.2e-10 39.3 0.0 9.4e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 KEZ41712.1 - 2.6e-51 174.1 0.0 4e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KEZ41712.1 - 1.5e-18 67.0 0.6 3e-18 66.1 0.6 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KEZ41712.1 - 7.2e-06 25.6 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KEZ41712.1 - 0.0033 17.2 0.1 0.0077 16.0 0.1 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain PAS_9 PF13426.7 KEZ41712.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain CPSase_L_D2 PF02786.17 KEZ41712.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain MFS_1 PF07690.16 KEZ41713.1 - 1.2e-27 96.8 24.6 1.5e-27 96.4 24.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.6 KEZ41713.1 - 0.81 10.0 7.3 0.078 13.3 1.7 2.2 2 1 0 2 2 2 0 Stage V sporulation protein AB DUF1996 PF09362.10 KEZ41714.1 - 5.1e-78 262.3 0.1 7e-78 261.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_2 PF12796.7 KEZ41714.1 - 4e-54 181.1 0.0 1.4e-13 51.2 0.0 7.9 1 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ41714.1 - 2.6e-42 142.7 4.8 7e-12 45.6 0.0 11.6 7 3 4 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ41714.1 - 1.7e-33 114.2 6.7 3e-08 33.8 0.0 11.4 6 2 6 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ41714.1 - 2.2e-33 110.5 8.6 0.00013 22.1 0.0 14.1 14 1 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 KEZ41714.1 - 8.4e-32 108.2 9.9 0.00089 19.6 0.0 13.2 13 1 0 13 13 13 5 Ankyrin repeat Abhydrolase_6 PF12697.7 KEZ41714.1 - 0.0019 18.8 0.2 0.006 17.2 0.2 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEZ41714.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 KEZ41714.1 - 0.018 14.6 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Frizzled PF01534.17 KEZ41715.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF676 PF05057.14 KEZ41716.1 - 2.3e-06 27.3 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KEZ41716.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 1 1 2 2 2 1 PGAP1-like protein Cutinase PF01083.22 KEZ41716.1 - 0.00041 20.4 0.0 0.00058 19.9 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 KEZ41716.1 - 0.00074 20.2 0.1 0.00086 20.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ41716.1 - 0.0075 15.6 0.2 0.07 12.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KEZ41716.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LIDHydrolase PF10230.9 KEZ41716.1 - 0.052 13.1 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase LCAT PF02450.15 KEZ41716.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.25 KEZ41717.1 - 5.3e-34 117.8 0.0 1.2e-33 116.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41717.1 - 2.5e-22 79.4 0.0 3.9e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.23 KEZ41717.1 - 8.4e-20 70.9 2.2 2.2e-19 69.6 2.2 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ41717.1 - 6.2e-11 42.2 0.4 1.7e-10 40.8 0.4 1.8 1 0 0 1 1 1 1 Berberine and berberine like APH PF01636.23 KEZ41717.1 - 0.012 15.5 3.5 0.057 13.3 0.4 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cytokin-bind PF09265.10 KEZ41717.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ribonuc_L-PSP PF01042.21 KEZ41718.1 - 8.6e-21 74.2 0.0 1e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MscS_porin PF12795.7 KEZ41719.1 - 0.0089 15.6 0.4 0.0089 15.6 0.4 2.0 3 0 0 3 3 3 1 Mechanosensitive ion channel porin domain NAD_binding_10 PF13460.6 KEZ41720.1 - 1.9e-20 73.5 0.0 2.3e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ41720.1 - 1.2e-08 34.8 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ41720.1 - 1.4e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family PAC2 PF09754.9 KEZ41720.1 - 0.03 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 PAC2 family TrkA_N PF02254.18 KEZ41720.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KEZ41720.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KEZ41720.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_2 PF07719.17 KEZ41722.1 - 0.021 14.9 7.0 0.062 13.4 0.4 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ41722.1 - 0.034 13.8 0.2 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 KEZ41722.1 - 0.038 14.3 2.9 0.1 12.9 0.5 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ41722.1 - 0.78 9.7 6.5 1.3 9.0 0.5 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.6 KEZ41723.1 - 3.5e-15 56.5 0.0 5.8e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ41723.1 - 6.4e-08 33.1 0.0 1.5e-05 25.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ41723.1 - 0.0021 18.1 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.8 KEZ41724.1 - 1.8e-11 43.5 0.0 3.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41724.1 - 0.038 14.1 0.4 0.038 14.1 0.4 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KEZ41725.1 - 1.2e-12 48.1 7.2 0.039 14.8 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41725.1 - 0.025 14.9 1.0 0.46 10.8 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 KEZ41726.1 - 2.9e-77 260.4 0.0 3.6e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PLDc_2 PF13091.6 KEZ41727.1 - 1.1e-15 57.7 1.1 3.1e-07 30.3 0.0 4.2 4 0 0 4 4 4 3 PLD-like domain PLDc PF00614.22 KEZ41727.1 - 1.5e-15 56.6 0.9 3.8e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif GLTP PF08718.11 KEZ41728.1 - 9.2e-45 152.6 0.1 4.7e-44 150.3 0.0 1.8 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) DUF2451 PF10474.9 KEZ41728.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Glyco_trans_1_4 PF13692.6 KEZ41729.1 - 1.4e-16 61.2 0.0 2.8e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KEZ41729.1 - 7.3e-16 58.2 0.0 1.5e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KEZ41729.1 - 5.6e-09 36.1 0.0 2e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3492) Glyco_hydro_114 PF03537.13 KEZ41730.1 - 1.4e-85 286.3 0.3 1.7e-85 286.1 0.3 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.21 KEZ41731.1 - 0.099 12.5 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide deacetylase Abhydrolase_3 PF07859.13 KEZ41732.1 - 5.7e-29 101.5 0.0 8.1e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_1 PF00583.25 KEZ41732.1 - 5e-12 46.1 0.1 9.5e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Say1_Mug180 PF10340.9 KEZ41732.1 - 5.2e-10 38.7 0.0 7.8e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Acetyltransf_10 PF13673.7 KEZ41732.1 - 2e-07 31.0 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ41732.1 - 0.0016 18.9 0.1 0.0048 17.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ41732.1 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KEZ41732.1 - 0.031 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain COesterase PF00135.28 KEZ41732.1 - 0.094 11.6 0.6 0.97 8.2 0.6 2.0 1 1 0 1 1 1 0 Carboxylesterase family MT-A70 PF05063.14 KEZ41732.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 MT-A70 adh_short PF00106.25 KEZ41733.1 - 4.6e-37 127.4 0.1 7e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41733.1 - 2.4e-24 86.2 0.0 4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41733.1 - 2.5e-09 37.3 0.3 7.4e-09 35.8 0.3 1.7 1 1 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KEZ41733.1 - 0.0049 15.7 0.0 0.0073 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.19 KEZ41733.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KEZ41734.1 - 2.1e-36 125.2 0.1 2.6e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41734.1 - 4.3e-27 95.2 0.0 6.1e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41734.1 - 7.7e-09 35.7 0.2 1.5e-08 34.8 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ41734.1 - 0.00042 19.9 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ41734.1 - 0.0083 15.2 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 KEZ41734.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PRP38 PF03371.15 KEZ41734.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 PRP38 family UDPG_MGDP_dh_N PF03721.14 KEZ41734.1 - 0.31 10.6 1.0 2.8 7.5 0.6 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KEZ41735.1 - 2e-05 24.0 0.0 3.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain CENP-C_mid PF15620.6 KEZ41736.1 - 0.031 14.2 4.3 3.1 7.7 0.3 2.3 2 0 0 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region Gemini_mov PF01708.16 KEZ41736.1 - 0.064 13.0 0.7 16 5.3 0.1 2.6 2 0 0 2 2 2 0 Geminivirus putative movement protein Lem_TRP PF08262.11 KEZ41736.1 - 0.41 10.7 2.1 29 5.0 0.2 2.5 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide CENP-B_dimeris PF09026.10 KEZ41736.1 - 5.4 7.5 7.7 24 5.4 0.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CFEM PF05730.11 KEZ41738.1 - 6.2e-17 61.5 12.0 1.2e-16 60.6 12.0 1.5 1 0 0 1 1 1 1 CFEM domain EutH PF04346.12 KEZ41738.1 - 0.013 14.7 8.0 0.022 13.9 1.3 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation protein, EutH DUF1624 PF07786.12 KEZ41740.1 - 0.0046 16.5 1.5 0.0063 16.1 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) MARVEL PF01284.23 KEZ41740.1 - 0.0072 16.4 1.8 0.011 15.8 1.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Cyt_bd_oxida_II PF02322.15 KEZ41740.1 - 0.03 13.7 2.0 0.035 13.5 2.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Neisseria_TspB PF05616.13 KEZ41740.1 - 2.5 6.5 5.0 2.9 6.3 5.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Tyrosinase PF00264.20 KEZ41742.1 - 3e-31 109.4 0.0 4.8e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_S9 PF00326.21 KEZ41743.1 - 7.9e-43 146.4 0.1 1.3e-42 145.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 KEZ41743.1 - 5.1e-15 55.2 0.0 1.3e-14 53.8 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Esterase PF00756.20 KEZ41743.1 - 0.0012 18.5 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KEZ41743.1 - 0.0038 16.8 0.2 0.0075 15.8 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KEZ41743.1 - 0.01 15.1 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KEZ41743.1 - 0.06 12.9 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) SBP_bac_1 PF01547.25 KEZ41743.1 - 0.096 12.6 0.0 0.38 10.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein Glyco_hydro_1 PF00232.18 KEZ41744.1 - 1e-143 479.1 0.0 1.2e-143 478.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Bac_rhamnosid6H PF17389.2 KEZ41745.1 - 2.4e-117 392.0 0.3 3.3e-117 391.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 KEZ41745.1 - 7.8e-53 178.8 0.0 1.6e-52 177.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 KEZ41745.1 - 4.3e-30 103.7 0.0 2e-29 101.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 KEZ41745.1 - 1e-16 60.4 0.0 3.3e-16 58.8 0.0 2.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Cyclase PF04199.13 KEZ41746.1 - 1.6e-15 57.6 0.0 2.2e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 KEZ41747.1 - 2.6e-68 230.9 20.2 3.2e-68 230.7 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41747.1 - 1.6e-17 63.5 31.8 1.5e-10 40.6 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3272 PF11676.8 KEZ41747.1 - 0.012 15.9 0.2 0.03 14.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) Fungal_trans PF04082.18 KEZ41748.1 - 2.6e-22 79.1 0.0 8.5e-22 77.4 0.0 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41748.1 - 1.5e-06 28.2 7.7 2.5e-06 27.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 KEZ41749.1 - 1.4e-44 152.4 0.0 1.3e-43 149.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.12 KEZ41750.1 - 1.5e-43 148.8 0.0 2.2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KEZ41750.1 - 2e-30 105.8 0.2 3e-30 105.2 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KEZ41750.1 - 8.9e-14 51.5 0.0 1.8e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KEZ41750.1 - 3.2e-06 27.4 0.9 3.5e-05 24.1 0.2 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site AAA_18 PF13238.6 KEZ41750.1 - 2e-05 25.1 0.1 0.00032 21.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 KEZ41750.1 - 4.4e-05 23.3 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase SKI PF01202.22 KEZ41750.1 - 0.00028 21.0 0.0 0.00056 20.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KEZ41750.1 - 0.00045 20.4 0.0 0.0019 18.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_PrkA PF08298.11 KEZ41750.1 - 0.00094 18.2 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 KEZ41750.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KEZ41750.1 - 0.0044 16.8 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 KEZ41750.1 - 0.0045 16.9 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase dNK PF01712.19 KEZ41750.1 - 0.0091 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_16 PF13191.6 KEZ41750.1 - 0.013 15.9 0.1 0.084 13.3 0.0 2.3 3 0 0 3 3 2 0 AAA ATPase domain AAA PF00004.29 KEZ41750.1 - 0.014 15.8 0.0 0.05 14.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEZ41750.1 - 0.015 15.6 0.0 0.059 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain GDP_Man_Dehyd PF16363.5 KEZ41750.1 - 0.022 14.2 0.0 0.1 12.0 0.0 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase AAA_17 PF13207.6 KEZ41750.1 - 0.026 14.9 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KEZ41750.1 - 0.029 13.5 0.0 0.068 12.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein KR PF08659.10 KEZ41750.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 KR domain Rad17 PF03215.15 KEZ41750.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 KEZ41750.1 - 0.089 12.2 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KEZ41750.1 - 0.089 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 KEZ41750.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 KEZ41750.1 - 0.13 12.2 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KEZ41750.1 - 0.13 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KEZ41750.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin2 PF13189.6 KEZ41750.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_25 PF13481.6 KEZ41750.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ41750.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase adh_short PF00106.25 KEZ41751.1 - 2.9e-32 111.7 0.0 4.7e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41751.1 - 5.8e-22 78.4 0.0 1.7e-21 76.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41751.1 - 0.00024 21.1 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ41751.1 - 0.017 14.6 0.0 0.39 10.1 0.0 2.6 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KEZ41752.1 - 4.8e-22 78.5 0.0 7e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41752.1 - 7.1e-16 58.7 0.0 2.4e-15 57.0 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41752.1 - 3.6e-13 50.0 0.0 1.6e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41752.1 - 4e-11 43.5 0.0 8.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41752.1 - 1.5e-10 41.1 0.0 2e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ41752.1 - 1.3e-07 31.2 0.0 9.4e-07 28.4 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ41752.1 - 9.2e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KEZ41752.1 - 0.00012 21.6 0.0 0.00041 19.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KEZ41752.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ41752.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KEZ41752.1 - 0.042 13.2 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KEZ41752.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 KEZ41752.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_15 PF09445.10 KEZ41752.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase P22_portal PF16510.5 KEZ41752.1 - 0.23 10.0 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein NAD_binding_4 PF07993.12 KEZ41753.1 - 9.8e-66 221.5 0.0 2e-65 220.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KEZ41753.1 - 1.9e-58 198.1 0.0 3.1e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KEZ41753.1 - 1.5e-09 37.7 0.0 3.9e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KEZ41753.1 - 5.5e-09 36.2 0.0 1.4e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KEZ41753.1 - 8.6e-07 28.2 0.0 2.1e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KEZ41753.1 - 1.2e-05 26.2 0.0 0.00014 22.8 0.0 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 KEZ41753.1 - 0.0039 17.1 0.0 0.019 14.9 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEZ41753.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KEZ41753.1 - 0.063 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 KEZ41753.1 - 0.084 12.0 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Git3 PF11710.8 KEZ41754.1 - 1.6e-15 57.4 10.6 1.6e-15 57.4 10.6 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KEZ41754.1 - 8.7e-10 38.5 0.2 8.7e-10 38.5 0.2 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 KEZ41754.1 - 2.7e-08 33.5 4.1 3.7e-08 33.0 4.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sugar_tr PF00083.24 KEZ41756.1 - 9e-74 248.9 21.7 9.7e-59 199.4 5.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41756.1 - 7.5e-22 77.7 25.5 1.5e-21 76.8 19.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TPP_enzyme_N PF02776.18 KEZ41757.1 - 2.1e-45 154.4 0.1 1.7e-44 151.5 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEZ41757.1 - 2.5e-25 89.0 0.0 1.1e-24 87.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ41757.1 - 1.6e-19 70.0 0.0 2.8e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.25 KEZ41758.1 - 3.3e-29 101.8 0.0 4.1e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41758.1 - 3e-26 92.4 0.0 3.8e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41758.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 KR domain Fungal_trans PF04082.18 KEZ41759.1 - 0.00013 21.1 0.1 0.00018 20.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.22 KEZ41760.1 - 4.2e-37 127.9 0.0 5.8e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Con-6 PF10346.9 KEZ41761.1 - 8.3e-13 48.1 2.2 1.2e-12 47.7 2.2 1.2 1 0 0 1 1 1 1 Conidiation protein 6 DUF5633 PF18656.1 KEZ41761.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5633) AMP-binding PF00501.28 KEZ41762.1 - 4.5e-80 269.3 0.0 5.8e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ41762.1 - 2.2e-13 50.9 0.4 1.1e-12 48.7 0.1 2.4 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.12 KEZ41763.1 - 9.8e-18 64.0 1.4 1.7e-17 63.3 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ41763.1 - 1.3e-12 47.9 0.0 2.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ41763.1 - 5.6e-07 30.7 0.0 1.6e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEZ41763.1 - 0.0012 18.2 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KEZ41763.1 - 0.038 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short_C2 PF13561.6 KEZ41764.1 - 2.7e-58 197.3 0.5 3.4e-58 197.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ41764.1 - 1.5e-45 155.1 0.4 1.8e-45 154.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 KEZ41765.1 - 7.3e-47 159.9 0.0 9.4e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEZ41765.1 - 8.7e-11 41.4 0.1 6.5e-10 38.5 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KEZ41765.1 - 0.0018 17.8 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Pyr_redox_3 PF13738.6 KEZ41766.1 - 7.6e-15 55.0 0.0 5e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEZ41766.1 - 2.3e-14 52.7 0.0 3.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KEZ41766.1 - 5.6e-10 38.9 0.0 1.9e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ41766.1 - 2.7e-09 36.6 0.6 8.2e-09 35.0 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEZ41766.1 - 6.3e-06 26.3 3.5 2e-05 24.8 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ41766.1 - 3.5e-05 23.6 0.0 0.13 11.8 0.0 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ41766.1 - 0.0036 16.1 0.1 1.3 7.7 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.20 KEZ41766.1 - 0.0058 16.7 0.2 0.055 13.5 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ41766.1 - 0.014 14.8 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KEZ41766.1 - 0.014 14.7 0.0 0.72 9.0 0.0 2.2 1 1 1 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KEZ41766.1 - 0.035 13.2 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KEZ41766.1 - 0.23 12.1 0.4 43 4.8 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 KEZ41767.1 - 4.9e-06 26.7 0.3 1.1e-05 25.5 0.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 KEZ41768.1 - 9.4e-35 120.2 37.2 9.4e-35 120.2 37.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KEZ41769.1 - 5.6e-14 51.8 0.2 9.1e-14 51.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41769.1 - 0.00031 20.8 10.6 0.00068 19.7 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 KEZ41769.1 - 0.19 11.8 4.8 0.42 10.7 4.8 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FMO-like PF00743.19 KEZ41770.1 - 8e-19 67.4 0.0 1.5e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ41770.1 - 2e-10 40.7 0.0 5.8e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ41770.1 - 1.4e-08 34.4 0.0 6.6e-06 25.6 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ41770.1 - 8.1e-06 25.3 0.0 0.0084 15.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ41770.1 - 2.4e-05 23.6 0.0 0.0069 15.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEZ41770.1 - 5.4e-05 23.2 0.2 0.023 14.7 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KEZ41770.1 - 0.0033 17.1 0.0 4.7 6.7 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ41770.1 - 0.024 13.9 0.2 2.6 7.2 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Amino_oxidase PF01593.24 KEZ41770.1 - 0.14 11.4 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Ring_hydroxyl_B PF00866.18 KEZ41770.1 - 0.33 11.0 1.8 17 5.5 0.1 3.0 3 0 0 3 3 3 0 Ring hydroxylating beta subunit adh_short PF00106.25 KEZ41771.1 - 9e-31 106.9 0.0 1.2e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41771.1 - 1.1e-24 87.3 0.0 1.6e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41771.1 - 8.7e-07 29.0 0.0 0.00062 19.7 0.0 2.2 2 0 0 2 2 2 2 KR domain NACHT PF05729.12 KEZ41772.1 - 9.8e-05 22.3 1.5 0.0004 20.3 0.3 2.6 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ41772.1 - 0.027 14.8 6.8 0.032 14.5 0.1 3.6 3 2 0 3 3 3 0 AAA domain Pox_A_type_inc PF04508.12 KEZ41772.1 - 0.028 14.3 2.4 0.044 13.7 0.5 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ABC_tran PF00005.27 KEZ41772.1 - 0.039 14.5 0.2 0.29 11.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 KEZ41772.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KEZ41772.1 - 0.083 13.0 0.3 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ41772.1 - 0.085 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KEZ41772.1 - 0.092 12.5 0.3 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ41772.1 - 0.12 12.3 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEZ41772.1 - 0.21 12.1 0.1 0.21 12.1 0.1 3.4 3 1 0 3 3 3 0 AAA domain FapA PF03961.13 KEZ41772.1 - 0.59 8.7 3.2 1.1 7.8 3.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF87 PF01935.17 KEZ41772.1 - 0.96 9.5 2.9 26 4.8 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Jnk-SapK_ap_N PF09744.9 KEZ41772.1 - 1.1 9.5 7.1 3.8 7.7 7.1 1.9 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Baculo_PEP_C PF04513.12 KEZ41772.1 - 7.9 6.5 14.6 0.32 11.0 5.4 3.1 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugar_tr PF00083.24 KEZ41773.1 - 3.4e-72 243.8 14.0 4.1e-72 243.5 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41773.1 - 1.1e-28 100.2 46.5 3.7e-24 85.3 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spa1_C PF18218.1 KEZ41773.1 - 0.072 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain Fungal_trans PF04082.18 KEZ41774.1 - 3.3e-14 52.5 0.1 4.8e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldose_epim PF01263.20 KEZ41775.1 - 1.7e-56 191.8 0.0 2.2e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase GMC_oxred_C PF05199.13 KEZ41777.1 - 4.3e-30 105.1 0.0 6.9e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KEZ41777.1 - 8.5e-21 74.6 0.0 1.2e-17 64.3 0.1 2.7 2 1 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEZ41777.1 - 0.00035 19.9 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ41777.1 - 0.0043 16.2 0.2 0.0064 15.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ41777.1 - 0.0048 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ41777.1 - 0.026 13.6 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KEZ41777.1 - 0.064 12.5 0.3 0.1 11.8 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KEZ41777.1 - 0.22 10.2 0.1 0.34 9.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.25 KEZ41778.1 - 1.6e-36 126.1 0.0 2.5e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41778.1 - 1.7e-17 63.6 0.0 2.5e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ41778.1 - 0.0003 19.7 0.0 0.00058 18.8 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase AAA_30 PF13604.6 KEZ41779.1 - 0.37 10.5 4.7 0.54 9.9 0.2 2.5 3 0 0 3 3 3 0 AAA domain TPR_10 PF13374.6 KEZ41779.1 - 2.1 8.3 4.3 5.6 7.0 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KEZ41780.1 - 1.2e-70 238.6 22.5 1.5e-70 238.3 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41780.1 - 3.4e-18 65.7 59.1 1.7e-17 63.4 27.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 KEZ41781.1 - 1e-153 512.2 0.0 1.2e-153 512.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ41781.1 - 9.6e-06 25.2 0.2 0.0062 16.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) PepSY PF03413.19 KEZ41781.1 - 0.05 14.2 0.1 30 5.3 0.0 3.4 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain Fungal_trans_2 PF11951.8 KEZ41782.1 - 3.6e-16 59.0 0.2 2.1e-15 56.5 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_N PF08240.12 KEZ41783.1 - 3.7e-23 81.5 0.9 3.7e-23 81.5 0.9 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ41783.1 - 4.2e-13 49.4 2.5 1.3e-11 44.6 1.0 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEZ41783.1 - 0.0013 18.1 0.2 0.002 17.5 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ILVD_EDD PF00920.21 KEZ41784.1 - 1.8e-209 696.7 1.2 2.1e-209 696.5 1.2 1.0 1 0 0 1 1 1 1 Dehydratase family NicO PF03824.16 KEZ41785.1 - 2e-57 194.7 4.8 2e-57 194.7 4.8 2.3 3 0 0 3 3 3 2 High-affinity nickel-transport protein Methyltransf_23 PF13489.6 KEZ41786.1 - 1.2e-14 54.4 0.0 2.6e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41786.1 - 4.6e-12 46.4 0.0 8.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41786.1 - 5.3e-11 43.1 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41786.1 - 1.8e-08 34.3 0.0 3.5e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41786.1 - 3.4e-07 30.9 0.0 1.4e-06 28.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ41786.1 - 0.0022 17.5 0.0 0.02 14.3 0.0 2.3 3 0 0 3 3 3 1 Putative methyltransferase Ubie_methyltran PF01209.18 KEZ41786.1 - 0.008 15.5 0.0 0.05 12.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ41786.1 - 0.012 15.2 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ41786.1 - 0.031 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KEZ41786.1 - 0.07 12.4 0.0 0.32 10.2 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 KEZ41786.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF2138 PF09909.9 KEZ41786.1 - 0.15 10.4 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Methyltransf_8 PF05148.15 KEZ41786.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Glyco_trans_4_4 PF13579.6 KEZ41788.1 - 0.029 14.8 0.3 0.38 11.2 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_hydro_6 PF01341.17 KEZ41789.1 - 1.5e-96 323.8 0.0 2e-96 323.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 PRCC PF10253.9 KEZ41789.1 - 0.17 12.6 1.6 0.28 11.9 1.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Aldo_ket_red PF00248.21 KEZ41790.1 - 2.5e-65 220.6 0.0 3e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SH3BGR PF04908.15 KEZ41791.1 - 9.9e-05 22.4 0.0 9.9e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein DEC-1_N PF04625.13 KEZ41791.1 - 0.015 14.3 4.3 0.027 13.5 4.3 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4611 PF15387.6 KEZ41791.1 - 3.2 8.0 20.0 2 8.7 11.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF908 PF06012.12 KEZ41791.1 - 4.5 6.6 10.8 19 4.5 7.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) IBR PF01485.21 KEZ41792.1 - 2.7e-08 33.9 22.0 1e-05 25.6 1.4 3.0 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain BET PF17035.5 KEZ41792.1 - 0.22 11.7 3.9 0.52 10.5 3.9 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation WD40 PF00400.32 KEZ41793.1 - 8.4e-77 251.1 22.3 1.6e-08 35.1 0.1 12.8 13 0 0 13 13 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41793.1 - 6.3e-51 170.6 0.0 0.0011 19.2 0.0 12.8 4 3 9 13 13 13 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ41793.1 - 5.2e-31 107.8 6.7 0.0005 19.1 0.1 11.7 2 2 10 12 12 12 10 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEZ41793.1 - 1.2e-24 85.6 7.3 1 9.4 0.0 12.4 12 0 0 12 12 12 6 WD40-like Beta Propeller Repeat NACHT PF05729.12 KEZ41793.1 - 8.6e-19 68.0 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.11 KEZ41793.1 - 1.2e-12 48.2 0.0 0.087 12.7 0.0 6.1 3 2 2 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KEZ41793.1 - 6.8e-12 45.3 9.3 0.22 10.8 0.0 8.6 3 2 5 9 9 9 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KEZ41793.1 - 3.2e-11 42.6 18.1 0.16 10.5 0.1 9.0 2 2 6 9 9 9 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KEZ41793.1 - 4.4e-10 38.6 2.6 0.68 8.4 0.0 5.8 3 3 3 6 6 6 3 Cytochrome D1 heme domain DUF1513 PF07433.11 KEZ41793.1 - 1.2e-07 31.2 10.3 0.031 13.4 0.4 6.2 4 3 0 6 6 6 2 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.9 KEZ41793.1 - 3.2e-07 29.9 7.9 13 5.5 0.0 9.5 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature SGL PF08450.12 KEZ41793.1 - 3.8e-07 30.0 1.1 0.13 11.8 0.0 5.6 1 1 3 5 5 5 2 SMP-30/Gluconolactonase/LRE-like region DPPIV_N PF00930.21 KEZ41793.1 - 4e-05 22.6 0.1 7.5 5.2 0.0 6.3 5 2 1 7 7 7 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5046 PF16465.5 KEZ41793.1 - 5.6e-05 22.7 2.0 0.25 10.8 0.0 4.5 4 1 0 5 5 5 1 Domain of unknown function (DUF5046) DUF642 PF04862.12 KEZ41793.1 - 0.00045 20.0 1.1 0.18 11.6 0.1 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF642) RAB3GAP2_N PF14655.6 KEZ41793.1 - 0.0073 15.6 0.9 17 4.5 0.0 5.5 6 1 0 7 7 7 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3748 PF12566.8 KEZ41793.1 - 0.0098 15.8 0.1 14 5.7 0.0 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF3748) HET-S PF17108.5 KEZ41793.1 - 0.015 15.0 1.6 0.051 13.3 1.6 1.9 1 0 0 1 1 1 0 N-terminal small S protein of HET, non-prionic DUF5570 PF17731.1 KEZ41793.1 - 0.019 15.1 16.7 9.4 6.4 0.1 7.2 6 2 3 9 9 9 0 Family of unknown function (DUF5570) IKI3 PF04762.12 KEZ41793.1 - 0.055 11.5 0.0 7 4.5 0.0 3.3 2 1 1 3 3 3 0 IKI3 family HET-s_218-289 PF11558.8 KEZ41793.1 - 0.055 13.5 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 Het-s 218-289 Phytase-like PF13449.6 KEZ41793.1 - 0.069 13.1 0.0 12 5.8 0.0 3.9 5 1 0 5 5 5 0 Esterase-like activity of phytase TruB_C PF09142.11 KEZ41793.1 - 0.15 11.9 5.4 62 3.5 0.1 6.4 9 0 0 9 9 9 0 tRNA Pseudouridine synthase II, C terminal Roc PF08477.13 KEZ41793.1 - 2.1 8.6 13.2 3.4 7.9 0.0 6.2 4 2 2 7 7 7 0 Ras of Complex, Roc, domain of DAPkinase Alg6_Alg8 PF03155.15 KEZ41794.1 - 1e-129 433.7 30.4 2.8e-82 277.2 12.8 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF2070 PF09843.9 KEZ41794.1 - 1.6 6.9 9.5 2.3 6.4 9.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Trp_oprn_chp PF09534.10 KEZ41795.1 - 0.01 15.7 0.3 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glycophorin_A PF01102.18 KEZ41795.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A DUF4690 PF15756.5 KEZ41795.1 - 0.098 13.3 0.9 0.22 12.1 0.1 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Herpes_gE PF02480.16 KEZ41795.1 - 0.21 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SURF4 PF02077.15 KEZ41797.1 - 5.9e-95 317.9 9.3 6.6e-95 317.7 9.3 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 KEZ41797.1 - 0.94 9.5 5.7 13 5.8 1.6 2.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1129 PF06570.11 KEZ41797.1 - 6.7 6.1 7.2 1.7 8.1 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) RRM_1 PF00076.22 KEZ41798.1 - 9.4e-15 54.2 0.1 1.5e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ41798.1 - 6.7e-05 22.5 0.0 7.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEZ41798.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-TAZ PF02135.16 KEZ41799.1 - 0.32 11.5 3.9 0.52 10.8 1.3 2.4 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2 PF00096.26 KEZ41799.1 - 0.66 10.6 31.1 1.3 9.6 0.5 6.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ41799.1 - 2.8 9.0 29.9 2.9 9.0 0.3 6.6 6 1 0 6 6 6 0 C2H2-type zinc finger Choline_kinase PF01633.20 KEZ41800.1 - 1.8e-50 171.5 0.0 7.1e-50 169.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KEZ41800.1 - 2.8e-08 34.0 0.2 2.8e-08 34.0 0.2 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family NPR3 PF03666.13 KEZ41801.1 - 8.7e-138 460.0 0.2 8.7e-138 460.0 0.2 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 DGF-1_C PF11040.8 KEZ41801.1 - 3.2 7.8 5.5 9.7 6.3 5.5 1.8 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Got1 PF04178.12 KEZ41802.1 - 3.1e-34 117.8 18.9 4.4e-34 117.3 18.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family PMP22_Claudin PF00822.20 KEZ41802.1 - 1.7 8.5 10.6 0.68 9.8 7.5 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family La PF05383.17 KEZ41804.1 - 1.1e-14 54.1 0.0 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 La domain Nop PF01798.18 KEZ41805.1 - 3.1e-73 246.0 0.0 4.4e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KEZ41805.1 - 3.6e-47 160.2 2.1 9.9e-47 158.8 2.1 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain Sugar_tr PF00083.24 KEZ41807.1 - 2.1e-32 112.6 30.2 3.2e-19 69.1 7.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41807.1 - 1.7e-22 79.9 24.5 6.8e-16 58.1 12.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 KEZ41807.1 - 0.013 15.5 2.4 0.013 15.5 2.4 3.5 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4131 PF13567.6 KEZ41807.1 - 0.16 11.6 6.7 9.5 5.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF2721 PF11026.8 KEZ41807.1 - 0.27 11.1 2.7 1.1 9.1 2.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Fungal_trans PF04082.18 KEZ41808.1 - 8.7e-21 74.1 0.1 1.4e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41808.1 - 1.7e-08 34.4 8.6 3.4e-08 33.5 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KEZ41809.1 - 4.7e-19 68.4 6.8 0.00017 22.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41809.1 - 2.2e-13 50.3 0.0 0.044 14.1 0.0 5.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KEZ41809.1 - 0.013 14.1 0.0 0.32 9.5 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KEZ41809.1 - 0.017 14.1 0.0 2.3 7.1 0.0 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEZ41809.1 - 0.035 12.7 0.3 0.43 9.2 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KEZ41809.1 - 0.058 13.3 0.2 7 6.5 0.0 3.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A RIC1 PF07064.13 KEZ41811.1 - 3.4e-93 311.7 1.7 4.9e-93 311.2 1.7 1.2 1 0 0 1 1 1 1 RIC1 CK_II_beta PF01214.18 KEZ41811.1 - 3.3e-57 193.3 3.6 1.2e-55 188.1 3.6 2.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit ANAPC4_WD40 PF12894.7 KEZ41811.1 - 0.018 15.3 0.0 0.62 10.4 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEZ41811.1 - 0.12 13.3 0.3 80 4.4 0.0 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat PAP2 PF01569.21 KEZ41812.1 - 9e-24 83.8 4.0 3e-23 82.1 1.7 2.6 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_L2_C PF03947.18 KEZ41813.1 - 1.3e-50 170.9 2.1 3.6e-50 169.4 2.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KEZ41813.1 - 2.3e-23 81.9 0.6 5.6e-23 80.7 0.6 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 KEZ41814.1 - 6.8e-45 151.9 0.0 1.3e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEZ41814.1 - 1.8e-33 115.1 0.0 3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ion_trans PF00520.31 KEZ41815.1 - 2.2e-108 361.1 80.0 4.7e-32 111.2 11.8 5.6 4 1 1 5 5 5 5 Ion transport protein MutS_V PF00488.21 KEZ41815.1 - 1.6e-41 142.4 0.0 2.7e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V GPHH PF16905.5 KEZ41815.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.8 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated HMG_box PF00505.19 KEZ41816.1 - 2.7e-12 46.9 1.1 2.7e-12 46.9 1.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEZ41816.1 - 0.00029 21.4 0.3 0.00029 21.4 0.3 1.9 2 0 0 2 2 2 1 HMG-box domain MATalpha_HMGbox PF04769.12 KEZ41816.1 - 0.0059 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box PHD PF00628.29 KEZ41817.1 - 4.1e-09 36.2 7.7 8.5e-09 35.2 7.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KEZ41817.1 - 0.0061 16.1 4.4 0.013 15.1 4.4 1.5 1 0 0 1 1 1 1 PHD-finger UAA PF08449.11 KEZ41818.1 - 3.3e-98 328.6 5.5 4.6e-98 328.2 5.5 1.1 1 0 0 1 1 1 1 UAA transporter family WD40 PF00400.32 KEZ41818.1 - 3.3e-11 43.6 3.3 0.4 11.6 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nuc_sug_transp PF04142.15 KEZ41818.1 - 1.2e-05 24.6 0.0 1.2e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter ANAPC4_WD40 PF12894.7 KEZ41818.1 - 0.037 14.3 0.0 5.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TMEM234 PF10639.9 KEZ41818.1 - 0.098 12.7 2.0 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF2613 PF11021.8 KEZ41818.1 - 2.3 8.4 5.0 1 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) EamA PF00892.20 KEZ41818.1 - 3.1 8.0 21.0 1.7 8.8 3.9 3.2 3 0 0 3 3 3 0 EamA-like transporter family A_deaminase PF00962.22 KEZ41819.1 - 3.9e-123 411.0 0.1 5e-123 410.6 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_1 PF00018.28 KEZ41820.1 - 1.9e-35 120.2 5.2 1.2e-13 50.4 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KEZ41820.1 - 1.6e-33 114.4 0.0 2.8e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 KEZ41820.1 - 1.7e-33 114.2 7.2 8.9e-13 47.9 0.3 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KEZ41820.1 - 1.3e-21 76.0 0.0 1.7e-07 30.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 KEZ41820.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 KEZ41820.1 - 0.0027 17.7 0.0 0.035 14.2 0.0 2.6 3 0 0 3 3 3 1 SH3 domain SH3_3 PF08239.11 KEZ41820.1 - 0.075 13.3 5.7 0.72 10.2 0.6 3.6 4 0 0 4 4 4 0 Bacterial SH3 domain Biotin_lipoyl_2 PF13533.6 KEZ41820.1 - 1.7 8.6 3.7 13 5.7 0.3 3.5 4 0 0 4 4 4 0 Biotin-lipoyl like TRAM_LAG1_CLN8 PF03798.16 KEZ41821.1 - 9.3e-50 169.1 14.6 9.3e-50 169.1 14.6 1.4 2 0 0 2 2 2 1 TLC domain DUF4219 PF13961.6 KEZ41821.1 - 0.12 12.1 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Mito_carr PF00153.27 KEZ41822.1 - 1.8e-51 172.0 1.3 1.6e-18 66.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.20 KEZ41824.1 - 7.8e-17 61.2 2.0 1e-16 60.8 2.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 KEZ41824.1 - 0.00053 20.2 8.0 0.00094 19.4 0.2 2.1 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 KEZ41824.1 - 0.00079 20.0 1.0 0.011 16.3 0.2 2.3 2 1 0 2 2 2 1 SlyX TolA_bind_tri PF16331.5 KEZ41824.1 - 0.0047 17.0 6.0 0.67 10.1 0.0 2.1 2 0 0 2 2 2 2 TolA binding protein trimerisation ADIP PF11559.8 KEZ41824.1 - 0.0065 16.6 6.0 0.32 11.1 1.7 2.0 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 KEZ41824.1 - 0.0066 16.8 2.9 0.012 16.0 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) HAP1_N PF04849.13 KEZ41824.1 - 0.015 14.5 0.3 0.017 14.3 0.3 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region PspA_IM30 PF04012.12 KEZ41824.1 - 0.034 13.7 3.4 0.087 12.4 3.4 1.5 1 1 0 1 1 1 0 PspA/IM30 family DUF4763 PF15960.5 KEZ41824.1 - 0.096 12.0 2.3 2 7.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF3450 PF11932.8 KEZ41824.1 - 0.097 12.0 4.5 1.4 8.2 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KEZ41824.1 - 0.11 13.0 4.2 2.5 8.6 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF16 Swi5 PF07061.11 KEZ41824.1 - 0.17 12.0 7.0 1.4 9.0 1.9 2.1 2 0 0 2 2 2 0 Swi5 Spc7 PF08317.11 KEZ41824.1 - 0.51 9.2 6.0 5.1 5.9 6.0 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KEZ41824.1 - 0.51 10.8 2.8 11 6.5 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 KEZ41824.1 - 0.98 9.5 7.4 3.3 7.8 0.1 2.8 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 KEZ41825.1 - 5.1e-38 129.8 11.0 5.1e-38 129.8 11.0 5.6 6 0 0 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KEZ41825.1 - 8.9e-16 57.7 6.8 8.9e-16 57.7 6.8 6.7 5 2 2 7 7 7 3 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KEZ41825.1 - 0.0047 17.2 5.7 0.0047 17.2 5.7 5.5 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) Nup54_57_C PF18570.1 KEZ41825.1 - 0.037 13.6 4.3 0.19 11.4 2.4 2.8 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain DUF812 PF05667.11 KEZ41825.1 - 0.05 12.5 47.9 0.22 10.4 2.9 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF812) Tweety PF04906.13 KEZ41825.1 - 2.6 6.6 6.8 0.54 8.9 0.2 2.4 2 0 0 2 2 2 0 Tweety IFT57 PF10498.9 KEZ41825.1 - 5.6 5.8 40.6 0.0059 15.6 16.2 3.5 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 Ank_5 PF13857.6 KEZ41826.1 - 2.9e-37 126.2 4.8 1.9e-10 40.8 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ41826.1 - 3.2e-32 110.9 0.8 7.2e-13 48.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ41826.1 - 2.9e-31 107.4 2.0 2.6e-11 43.8 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ41826.1 - 4.2e-27 91.2 0.5 0.0029 17.9 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KEZ41826.1 - 1.7e-22 78.8 3.3 0.0007 19.9 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat WD40 PF00400.32 KEZ41827.1 - 3.9e-42 141.4 17.6 4.5e-10 39.9 0.3 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41827.1 - 1.4e-06 28.5 0.1 0.57 10.5 0.0 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ41827.1 - 0.00058 18.6 1.9 3 6.4 0.0 3.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 AAA PF00004.29 KEZ41828.1 - 7.3e-16 58.8 0.0 2e-15 57.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KEZ41828.1 - 1.7e-11 44.1 0.0 4.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KEZ41828.1 - 1.5e-10 41.7 0.0 1.6e-09 38.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ41828.1 - 1.6e-08 34.9 0.0 5.1e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEZ41828.1 - 0.00021 21.7 0.0 0.00094 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KEZ41828.1 - 0.00032 20.7 0.0 0.0061 16.5 0.0 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KEZ41828.1 - 0.00052 19.9 0.3 0.0044 16.8 0.0 2.3 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 KEZ41828.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 NACHT domain End_beta_barrel PF12195.8 KEZ41828.1 - 0.037 14.0 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase AAA_18 PF13238.6 KEZ41828.1 - 0.04 14.5 0.0 0.087 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ41828.1 - 0.043 14.2 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KEZ41828.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ41828.1 - 0.057 12.7 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 KEZ41828.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UvrD-helicase PF00580.21 KEZ41828.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 KEZ41828.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KEZ41828.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KEZ41828.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_3 PF07726.11 KEZ41828.1 - 0.13 12.1 0.1 2 8.3 0.0 2.5 2 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KEZ41828.1 - 0.14 12.2 0.0 1.1 9.3 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ORC5_C PF14630.6 KEZ41828.1 - 0.16 11.4 0.5 2.8 7.4 0.5 2.1 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus NTPase_1 PF03266.15 KEZ41828.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 NTPase Baculo_11_kDa PF06143.11 KEZ41828.1 - 0.29 10.7 0.7 0.66 9.6 0.1 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Cpn60_TCP1 PF00118.24 KEZ41829.1 - 1.7e-171 571.1 0.3 2e-171 571.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KEZ41829.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 BRK domain His_Phos_1 PF00300.22 KEZ41830.1 - 1.2e-26 93.6 0.1 3e-26 92.3 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KEZ41830.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.22 KEZ41831.1 - 4e-188 625.6 0.7 4.5e-188 625.5 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ41831.1 - 0.11 11.9 0.0 1.3 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TRF PF08558.10 KEZ41832.1 - 1.1e-18 67.7 0.6 1.9e-18 66.9 0.6 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KEZ41832.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AIP3 PF03915.13 KEZ41832.1 - 0.097 11.7 0.1 0.22 10.6 0.1 1.5 1 0 0 1 1 1 0 Actin interacting protein 3 Myb_DNA-bind_6 PF13921.6 KEZ41832.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain bZIP_1 PF00170.21 KEZ41834.1 - 1.8e-07 31.2 12.4 3.6e-07 30.2 12.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KEZ41834.1 - 9.5e-06 25.6 15.4 5.4e-05 23.1 0.1 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 KEZ41834.1 - 0.0014 18.4 6.9 0.0022 17.8 6.9 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 KEZ41834.1 - 0.052 13.6 18.3 0.13 12.3 16.6 2.1 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 KEZ41834.1 - 0.064 13.8 14.6 0.089 13.3 14.0 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor HSP70 PF00012.20 KEZ41834.1 - 0.084 11.0 3.5 0.11 10.7 3.5 1.1 1 0 0 1 1 1 0 Hsp70 protein TFIIA PF03153.13 KEZ41834.1 - 0.09 12.8 10.6 0.1 12.6 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PSI_PsaF PF02507.15 KEZ41834.1 - 0.19 11.6 0.3 0.36 10.6 0.3 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III V_ATPase_I PF01496.19 KEZ41834.1 - 0.2 9.6 2.7 0.26 9.2 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.6 KEZ41834.1 - 0.62 9.6 7.4 0.88 9.1 7.4 1.2 1 0 0 1 1 1 0 TMCO5 family ADIP PF11559.8 KEZ41834.1 - 1.4 9.0 16.2 3.4 7.8 16.3 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DASH_Dad1 PF08649.10 KEZ41835.1 - 1.8e-27 95.3 2.1 2.7e-27 94.7 2.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KEZ41835.1 - 0.064 13.2 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 Ras PF00071.22 KEZ41836.1 - 6.6e-46 155.9 0.0 8.8e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ41836.1 - 8.1e-20 71.2 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ41836.1 - 6.1e-05 22.5 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KEZ41836.1 - 0.049 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Skp1_POZ PF03931.15 KEZ41837.1 - 1.5e-08 34.6 0.0 2.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.13 KEZ41838.1 - 9.6e-51 171.9 0.1 2.1e-50 170.8 0.0 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KEZ41838.1 - 1.3e-05 25.8 1.3 1.5e-05 25.6 0.5 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PRMT5_TIM PF17285.2 KEZ41839.1 - 7.1e-69 231.8 0.0 9.6e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KEZ41839.1 - 3.6e-66 222.3 0.0 5.7e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KEZ41839.1 - 1.6e-55 187.7 0.0 2.6e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KEZ41839.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein OB_NTP_bind PF07717.16 KEZ41840.1 - 1.6e-23 82.8 0.2 4.4e-22 78.2 0.1 3.0 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KEZ41840.1 - 2.2e-18 66.5 0.0 5.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KEZ41840.1 - 1.9e-10 41.1 0.0 8.4e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ41840.1 - 8.3e-08 32.2 0.2 1.6e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEZ41840.1 - 3.3e-05 24.2 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KEZ41840.1 - 7.7e-05 22.4 0.1 0.0003 20.5 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KEZ41840.1 - 0.0028 18.0 0.1 0.0053 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ41840.1 - 0.0028 17.4 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KEZ41840.1 - 0.004 16.3 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 KEZ41840.1 - 0.0099 15.9 0.2 0.019 14.9 0.2 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_23 PF13476.6 KEZ41840.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ41840.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AMP-binding PF00501.28 KEZ41842.1 - 1.7e-91 307.0 0.0 2e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Gly_transf_sug PF04488.15 KEZ41843.1 - 5.3e-17 62.2 0.0 8.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Band_7 PF01145.25 KEZ41844.1 - 4.9e-26 91.8 1.4 9.7e-26 90.9 1.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KEZ41844.1 - 0.11 12.2 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family ANAPC10 PF03256.16 KEZ41845.1 - 5.6e-45 153.3 0.0 1e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Ank_2 PF12796.7 KEZ41846.1 - 3.3e-33 114.1 0.0 7.8e-11 42.4 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ41846.1 - 1.2e-26 92.7 0.2 7.9e-10 39.1 0.0 6.3 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ41846.1 - 1.3e-25 89.1 1.0 4.7e-08 33.1 0.1 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEZ41846.1 - 1.3e-24 85.5 4.2 0.0014 19.0 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KEZ41846.1 - 3.5e-24 82.2 0.1 0.00016 21.8 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat SesA PF17107.5 KEZ41846.1 - 4.8e-07 30.0 0.0 2.1e-06 27.9 0.1 2.1 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KEZ41846.1 - 7.8e-05 22.1 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KEZ41846.1 - 0.012 15.9 0.0 0.07 13.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rx_N PF18052.1 KEZ41846.1 - 0.049 13.9 0.8 0.16 12.3 0.2 2.2 2 0 0 2 2 2 0 Rx N-terminal domain KAsynt_C_assoc PF16197.5 KEZ41846.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension DUF2384 PF09722.10 KEZ41846.1 - 0.083 12.9 2.3 4.5 7.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2384) FUSC PF04632.12 KEZ41846.1 - 0.65 8.5 5.7 0.14 10.6 1.6 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3425 PF11905.8 KEZ41847.1 - 3.5e-23 81.9 3.5 8.6e-23 80.7 3.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF4519 PF15012.6 KEZ41848.1 - 0.71 10.1 4.5 1.2 9.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) E1-E2_ATPase PF00122.20 KEZ41849.1 - 1.3e-47 161.6 6.1 1.3e-47 161.6 6.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ41849.1 - 4e-17 63.2 0.0 1e-16 61.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ41849.1 - 2.7e-10 39.8 0.0 5.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ41849.1 - 0.0024 17.6 0.1 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ41849.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Phage_fiber_C PF06820.12 KEZ41849.1 - 0.13 12.7 0.5 0.41 11.0 0.1 2.1 2 0 0 2 2 2 0 Putative prophage tail fibre C-terminus Mito_carr PF00153.27 KEZ41850.1 - 2.6e-29 101.0 5.2 6.6e-14 51.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 KEZ41851.1 - 3e-101 339.1 0.0 3.8e-101 338.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KEZ41851.1 - 0.087 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone CTD_bind PF04818.13 KEZ41852.1 - 2.5e-08 34.6 0.0 5.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KEZ41852.1 - 7.6e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Astro_capsid_p PF12226.8 KEZ41852.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein WD40 PF00400.32 KEZ41853.1 - 0.0019 19.0 8.1 1.1 10.2 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat PknG_TPR PF16918.5 KEZ41854.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat Vg_Tdu PF07545.14 KEZ41854.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Vestigial/Tondu family Nop PF01798.18 KEZ41855.1 - 1.2e-76 257.2 0.1 1.2e-76 257.2 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KEZ41855.1 - 6.9e-16 58.4 0.1 6.9e-16 58.4 0.1 2.9 3 0 0 3 3 3 1 NOP5NT (NUC127) domain TSGP1 PF07771.11 KEZ41855.1 - 7.5 6.7 25.7 7.2 6.8 10.6 2.7 2 0 0 2 2 2 0 Tick salivary peptide group 1 vATP-synt_AC39 PF01992.16 KEZ41856.1 - 2.4e-103 346.2 0.0 2.7e-103 346.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 KEZ41857.1 - 2.7e-23 81.9 0.5 2.7e-23 81.9 0.5 2.6 2 1 1 3 3 3 1 Ribosomal protein S15 TSA PF03249.13 KEZ41857.1 - 0.022 13.6 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Type specific antigen Ribosomal_S2 PF00318.20 KEZ41858.1 - 7.1e-29 100.6 0.1 5.1e-16 58.6 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KEZ41858.1 - 9.2e-07 30.1 14.4 1.6e-06 29.4 14.4 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus VTC PF09359.10 KEZ41859.1 - 9.8e-89 297.4 0.1 9.8e-89 297.4 0.1 1.9 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KEZ41859.1 - 1.4e-11 44.6 4.0 1.4e-11 44.6 4.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KEZ41859.1 - 2.4e-10 40.9 15.2 2.5e-06 27.7 1.8 3.2 2 1 2 4 4 4 2 SPX domain MgtE PF01769.16 KEZ41859.1 - 0.017 15.5 0.2 0.03 14.7 0.2 1.2 1 0 0 1 1 1 0 Divalent cation transporter KxDL PF10241.9 KEZ41859.1 - 0.13 12.6 0.2 0.69 10.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein TBCC_N PF16752.5 KEZ41859.1 - 2 8.9 5.0 0.97 9.9 1.5 2.2 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain AAA_5 PF07728.14 KEZ41860.1 - 4.4e-12 46.2 0.0 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEZ41860.1 - 8.8e-11 42.2 0.0 3.5e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KEZ41860.1 - 1.4e-06 28.8 0.0 3.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KEZ41860.1 - 0.00014 21.4 0.0 0.51 9.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEZ41860.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KEZ41860.1 - 0.026 14.9 0.1 3.8 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain Torsin PF06309.11 KEZ41860.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_6 PF12774.7 KEZ41860.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 KEZ41860.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Nic96 PF04097.14 KEZ41862.1 - 4.5e-221 735.6 0.0 5.7e-221 735.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KEZ41862.1 - 4.4e-09 37.1 63.9 1e-05 26.3 23.8 3.3 2 1 1 3 3 3 2 Nucleoporin FG repeat region Drf_FH1 PF06346.12 KEZ41862.1 - 4.3 7.1 8.4 8.8 6.0 8.4 1.4 1 0 0 1 1 1 0 Formin Homology Region 1 FGGY_C PF02782.16 KEZ41863.1 - 3.2e-52 177.2 0.2 5.7e-52 176.3 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEZ41863.1 - 1.4e-19 70.6 0.4 6e-16 58.7 0.1 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Myb_DNA-binding PF00249.31 KEZ41864.1 - 4.7e-11 42.7 0.0 1.4e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KEZ41864.1 - 0.0004 20.2 0.1 0.0013 18.5 0.1 1.9 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KEZ41864.1 - 0.016 15.4 0.6 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain DS PF01916.17 KEZ41865.1 - 1.7e-76 257.2 2.0 8.7e-36 123.6 0.5 3.3 1 1 2 3 3 3 3 Deoxyhypusine synthase APH PF01636.23 KEZ41865.1 - 5e-07 29.9 0.9 9.4e-07 29.0 0.9 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEZ41865.1 - 0.043 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family HSF_DNA-bind PF00447.17 KEZ41866.1 - 7.4e-29 100.2 4.5 1.8e-28 99.0 0.3 2.5 2 0 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 KEZ41866.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Ets-domain Exonuc_VII_L PF02601.15 KEZ41866.1 - 0.84 9.1 4.6 0.33 10.5 1.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit MSP7_C PF12948.7 KEZ41866.1 - 1.6 9.4 6.4 25 5.5 1.4 3.3 3 0 0 3 3 3 0 MSP7-like protein C-terminal domain APG6_N PF17675.1 KEZ41866.1 - 2.3 8.8 19.2 0.11 13.0 9.0 2.7 3 1 0 3 3 3 0 Apg6 coiled-coil region TMPIT PF07851.13 KEZ41866.1 - 2.9 7.0 5.9 5.7 6.1 5.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Radial_spoke_3 PF06098.11 KEZ41866.1 - 8.7 5.5 16.0 0.27 10.5 9.9 1.5 2 0 0 2 2 2 0 Radial spoke protein 3 Pro_isomerase PF00160.21 KEZ41867.1 - 2.5e-47 161.1 0.0 2.8e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 KEZ41868.1 - 5.5e-12 46.3 0.0 3.1e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain ATP-grasp_2 PF08442.10 KEZ41870.1 - 1.1e-75 253.7 0.5 1.1e-75 253.7 0.5 1.4 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KEZ41870.1 - 1e-25 90.3 0.2 2.5e-25 89.1 0.2 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KEZ41870.1 - 2.1e-09 37.1 0.1 4.8e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KEZ41870.1 - 0.0012 18.7 0.3 0.0061 16.3 0.1 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF1024 PF06260.12 KEZ41870.1 - 0.099 12.9 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) APH PF01636.23 KEZ41871.1 - 0.73 9.7 7.3 0.076 12.9 0.6 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family RTP1_C1 PF10363.9 KEZ41872.1 - 2.9e-27 95.1 4.5 1.5e-24 86.3 0.0 4.5 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KEZ41872.1 - 3.5e-14 52.2 1.0 9.6e-14 50.8 1.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Dymeclin PF09742.9 KEZ41872.1 - 0.008 14.7 4.3 0.022 13.2 4.3 1.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Thr_synth_N PF14821.6 KEZ41873.1 - 1.1e-28 99.3 0.0 2.3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 KEZ41873.1 - 7.7e-18 64.9 0.0 4.2e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MARVEL PF01284.23 KEZ41874.1 - 1.1e-06 28.7 13.1 1.4e-06 28.4 13.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 KEZ41875.1 - 1.2e-151 504.6 0.0 1.4e-151 504.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ41875.1 - 1.7e-12 47.3 0.4 8.3e-12 45.1 0.2 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KEZ41875.1 - 1.4e-09 37.6 0.1 2.3e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEZ41875.1 - 7.4e-09 35.0 0.2 1.4e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KEZ41875.1 - 1.8e-06 27.5 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KEZ41875.1 - 0.0051 15.4 0.0 0.007 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KEZ41875.1 - 0.0065 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS BRK PF07533.16 KEZ41875.1 - 0.12 12.0 0.6 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 BRK domain DUF2235 PF09994.9 KEZ41876.1 - 2.3e-30 106.0 0.1 5.4e-30 104.7 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ank_4 PF13637.6 KEZ41879.1 - 1.3e-11 44.8 2.9 2.3e-06 28.0 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ41879.1 - 2.4e-11 44.0 1.1 2e-05 25.1 0.0 3.9 3 3 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ41879.1 - 7.4e-05 22.9 1.2 0.27 11.9 0.0 5.4 6 1 1 7 7 7 1 Ankyrin repeat Ank PF00023.30 KEZ41879.1 - 0.00035 20.9 9.6 0.12 12.9 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEZ41879.1 - 0.0032 17.7 3.9 0.021 15.1 0.1 3.6 2 2 2 4 4 4 1 Ankyrin repeats (many copies) DUF3867 PF12983.7 KEZ41879.1 - 0.017 15.2 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) WD40 PF00400.32 KEZ41880.1 - 2.2e-58 192.8 10.6 1.9e-09 38.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ41880.1 - 2.1e-22 79.2 0.4 0.00089 19.5 0.0 6.4 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ41880.1 - 3.3e-18 65.7 0.0 0.05 12.5 0.0 6.0 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5046 PF16465.5 KEZ41880.1 - 2.6e-08 33.6 0.0 0.0029 17.1 0.0 3.3 1 1 2 3 3 3 2 Domain of unknown function (DUF5046) Nup160 PF11715.8 KEZ41880.1 - 2.8e-07 29.6 5.2 0.3 9.7 0.0 5.4 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEZ41880.1 - 1.2e-05 24.2 4.0 1.8 7.2 0.1 4.6 1 1 3 5 5 5 3 Nup133 N terminal like WD40_like PF17005.5 KEZ41880.1 - 7e-05 22.3 0.0 0.1 11.9 0.0 3.0 1 1 2 3 3 3 2 WD40-like domain NACHT PF05729.12 KEZ41880.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ret2_MD PF18528.1 KEZ41880.1 - 0.0015 18.9 0.0 48 4.4 0.0 4.6 3 1 1 4 4 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nbas_N PF15492.6 KEZ41880.1 - 0.0024 17.2 3.0 17 4.6 0.1 4.7 1 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 KEZ41880.1 - 0.0055 15.1 0.0 15 3.8 0.0 3.1 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KEZ41880.1 - 0.0094 15.6 3.6 17 5.2 0.1 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 KEZ41880.1 - 0.013 15.5 10.0 40 4.3 0.1 6.3 7 0 0 7 7 6 0 WD40-like Beta Propeller Repeat AnfG_VnfG PF03139.15 KEZ41880.1 - 0.028 14.5 0.0 1.8 8.7 0.0 3.5 2 2 2 4 4 4 0 Vanadium/alternative nitrogenase delta subunit Me-amine-dh_H PF06433.11 KEZ41880.1 - 0.042 12.7 0.0 0.74 8.6 0.0 2.6 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) HTH_20 PF12840.7 KEZ41880.1 - 0.062 13.4 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 KEZ41881.1 - 2.8e-30 105.4 30.1 2.8e-30 105.4 30.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HgmA PF04209.13 KEZ41882.1 - 1.1e-193 643.7 0.0 1.9e-193 643.0 0.0 1.3 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.18 KEZ41882.1 - 3.2e-12 46.1 0.1 5e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KEZ41883.1 - 3.4e-52 177.7 0.0 3.4e-47 161.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAA_hydrolase PF01557.18 KEZ41884.1 - 2.2e-33 115.8 0.0 5.5e-33 114.5 0.0 1.6 1 1 1 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KEZ41884.1 - 2.6e-32 111.2 0.1 9.2e-32 109.4 0.1 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.16 KEZ41885.1 - 9.4e-09 34.6 34.9 7e-08 31.8 34.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEZ41885.1 - 6.4e-08 32.5 6.5 1.7e-07 31.1 6.5 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KEZ41885.1 - 0.065 12.1 19.7 0.11 11.4 11.0 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter TauD PF02668.16 KEZ41886.1 - 1.4e-28 100.4 0.1 2.1e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HpcH_HpaI PF03328.14 KEZ41888.1 - 6.2e-21 74.6 0.0 9.7e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family AA_permease_2 PF13520.6 KEZ41889.1 - 1.3e-55 189.0 27.8 1.6e-55 188.7 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ41889.1 - 2.7e-19 69.1 21.9 2.7e-19 69.1 21.9 2.2 2 0 0 2 2 2 2 Amino acid permease DUF3176 PF11374.8 KEZ41890.1 - 1.4e-09 38.1 1.7 1.4e-09 38.1 1.7 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3176) Methyltransf_23 PF13489.6 KEZ41891.1 - 3.3e-15 56.3 0.0 6.3e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41891.1 - 1.7e-08 35.0 0.0 1.2e-07 32.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41891.1 - 3.4e-07 30.9 0.1 1.8e-05 25.3 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ41891.1 - 0.00018 20.9 0.0 0.0014 18.0 0.0 2.2 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEZ41891.1 - 0.00034 21.3 0.0 0.0026 18.5 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41891.1 - 0.0082 15.9 0.0 0.034 13.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.12 KEZ41891.1 - 0.021 14.4 0.0 0.059 12.9 0.0 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase F-box PF00646.33 KEZ41892.1 - 1.4e-06 28.0 0.1 3.5e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEZ41892.1 - 4.7e-05 23.2 0.1 0.0001 22.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KEZ41892.1 - 0.062 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 F-box FUSC_2 PF13515.6 KEZ41893.1 - 3.2e-18 66.1 12.3 6e-18 65.2 12.3 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 KEZ41893.1 - 4.8e-07 29.2 0.0 4.8e-07 29.2 0.0 2.5 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KEZ41893.1 - 4.9e-07 29.8 0.0 3.2e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KEZ41893.1 - 0.00018 20.5 10.6 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter ECH_1 PF00378.20 KEZ41894.1 - 3.5e-42 144.5 0.0 4.5e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ41894.1 - 8.1e-25 88.0 0.0 1.5e-24 87.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Acyl_transf_3 PF01757.22 KEZ41895.1 - 1.6e-25 89.9 21.3 2.2e-25 89.4 21.3 1.3 1 0 0 1 1 1 1 Acyltransferase family SH PF01445.17 KEZ41895.1 - 0.075 13.0 1.2 0.69 9.9 0.1 2.7 2 0 0 2 2 2 0 Viral small hydrophobic protein Abhydrolase_2 PF02230.16 KEZ41896.1 - 1.5e-19 70.7 0.0 4.5e-19 69.1 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KEZ41896.1 - 9.6e-05 22.0 0.2 0.0073 15.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEZ41896.1 - 0.0021 18.0 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ41896.1 - 0.014 14.7 1.1 3.6 6.8 0.2 3.0 2 1 1 3 3 3 0 Serine aminopeptidase, S33 ADH_N PF08240.12 KEZ41897.1 - 1.3e-28 99.0 0.5 2.8e-28 98.0 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ41897.1 - 2.1e-21 76.3 0.1 3.7e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ41897.1 - 0.0015 18.0 0.2 0.0055 16.1 0.2 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KEZ41897.1 - 0.013 16.6 0.0 0.021 15.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.25 KEZ41897.1 - 0.027 14.0 0.6 0.049 13.1 0.6 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KEZ41897.1 - 0.041 13.2 0.4 0.066 12.5 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glucokinase PF02685.16 KEZ41897.1 - 0.043 12.8 0.2 0.062 12.3 0.2 1.3 1 0 0 1 1 1 0 Glucokinase Pkinase PF00069.25 KEZ41898.1 - 1.5e-14 54.0 0.0 3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41898.1 - 1.3e-05 24.6 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HTH_32 PF13565.6 KEZ41901.1 - 8.3e-07 29.5 0.1 2.7e-05 24.7 0.0 2.5 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KEZ41901.1 - 0.024 14.3 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_29 PF13551.6 KEZ41901.1 - 0.026 14.5 3.4 0.17 11.9 0.2 3.4 3 2 0 3 3 3 0 Winged helix-turn helix HTH_23 PF13384.6 KEZ41901.1 - 0.026 14.3 1.0 0.96 9.3 0.0 2.7 3 1 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 KEZ41901.1 - 0.035 13.9 0.3 0.11 12.3 0.3 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 KEZ41901.1 - 0.065 13.4 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Bac_rhodopsin PF01036.18 KEZ41902.1 - 1e-27 97.2 30.1 1.3e-27 96.8 30.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Cation_ATPase_C PF00689.21 KEZ41904.1 - 7.3e-40 136.6 4.9 7.3e-40 136.6 4.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEZ41904.1 - 3.3e-37 127.8 1.5 9.1e-37 126.3 1.5 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KEZ41904.1 - 2.3e-19 69.3 0.0 8.6e-19 67.4 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ41904.1 - 2.9e-18 66.9 0.2 4.2e-17 63.1 0.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ41904.1 - 6.1e-09 35.4 1.5 5.6e-08 32.4 0.0 2.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ41904.1 - 1.4e-06 28.3 0.4 4e-05 23.5 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_9_N PF15420.6 KEZ41904.1 - 0.086 12.8 5.6 0.34 10.9 0.8 3.1 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Viral_Beta_CD PF04530.12 KEZ41904.1 - 0.13 12.5 0.0 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 Viral Beta C/D like family MatE PF01554.18 KEZ41904.1 - 0.22 11.1 7.4 4.2 7.0 1.7 3.1 2 0 0 2 2 2 0 MatE Sigma_reg_N PF13800.6 KEZ41904.1 - 1.1 9.6 3.4 25 5.3 0.4 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal MFS_1 PF07690.16 KEZ41905.1 - 1.8e-26 93.0 35.7 1.8e-26 93.0 35.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KEZ41906.1 - 2e-48 165.2 0.0 2.6e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41906.1 - 9.2e-06 25.7 10.6 1.9e-05 24.7 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 KEZ41906.1 - 0.63 10.4 6.5 1.4 9.4 6.5 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Hydantoinase_B PF02538.14 KEZ41907.1 - 1.3e-198 660.7 0.7 1.7e-198 660.2 0.7 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KEZ41907.1 - 1.4e-102 342.9 0.1 3.4e-101 338.3 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ41907.1 - 9.8e-56 188.3 3.4 3.8e-55 186.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Chitin_bind_1 PF00187.19 KEZ41908.1 - 9e-12 45.3 37.7 5.1e-07 30.1 16.9 2.7 2 1 0 2 2 2 2 Chitin recognition protein SKG6 PF08693.10 KEZ41908.1 - 7.2e-07 28.5 0.2 1.5e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KEZ41908.1 - 0.00015 21.6 0.0 0.00021 21.2 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 KEZ41908.1 - 0.0087 16.2 0.2 0.014 15.5 0.1 1.3 1 1 0 1 1 1 1 Podoplanin Presenilin PF01080.17 KEZ41908.1 - 0.05 12.4 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Presenilin Insulin_TMD PF17870.1 KEZ41908.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment FAD_binding_4 PF01565.23 KEZ41909.1 - 3.1e-22 78.8 1.9 5.4e-22 78.0 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ41909.1 - 1.3e-10 41.2 0.1 3e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like LysM PF01476.20 KEZ41911.1 - 1.1e-05 25.4 0.4 0.13 12.3 0.3 3.3 2 1 0 2 2 2 2 LysM domain Tyrosinase PF00264.20 KEZ41912.1 - 2.3e-40 139.3 0.0 3e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.19 KEZ41912.1 - 0.064 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box Ribonuc_L-PSP PF01042.21 KEZ41913.1 - 2.8e-26 91.9 0.0 3.7e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulfotransfer_4 PF17784.1 KEZ41914.1 - 5.4e-64 216.0 0.0 9.8e-64 215.1 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain BTB PF00651.31 KEZ41914.1 - 0.0021 18.3 0.1 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Sulfotransfer_3 PF13469.6 KEZ41914.1 - 0.0047 17.3 0.0 0.42 10.9 0.0 2.4 1 1 0 2 2 2 1 Sulfotransferase family Methyltransf_23 PF13489.6 KEZ41916.1 - 1.6e-20 73.6 0.0 2.4e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41916.1 - 6.1e-13 49.3 0.0 1.3e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41916.1 - 5.5e-11 43.0 0.0 1.2e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41916.1 - 7e-07 29.9 0.0 3.6e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41916.1 - 2.2e-06 27.5 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ41916.1 - 9e-05 21.9 0.0 0.0008 18.8 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ41916.1 - 0.00032 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KEZ41916.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KEZ41916.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KEZ41916.1 - 0.042 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 3HCDH_N PF02737.18 KEZ41917.1 - 3.7e-27 95.4 0.0 1e-26 93.9 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEZ41917.1 - 2.5e-12 47.3 0.0 2.2e-11 44.2 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Fig1 PF12351.8 KEZ41918.1 - 1.9e-06 27.9 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KEZ41918.1 - 0.0011 18.7 2.1 0.0018 18.0 2.1 1.5 1 1 0 1 1 1 1 SUR7/PalI family DUF5531 PF17671.1 KEZ41918.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5531) DUF1358 PF07096.11 KEZ41918.1 - 0.072 13.1 0.1 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1358) DUF3176 PF11374.8 KEZ41920.1 - 1e-38 131.8 0.2 2.6e-38 130.5 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) OppC_N PF12911.7 KEZ41920.1 - 0.1 12.6 0.5 4.2 7.4 0.1 2.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C zf_C2H2_10 PF18414.1 KEZ41920.1 - 0.12 11.9 0.1 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger NACHT PF05729.12 KEZ41922.1 - 0.0082 16.1 2.2 0.025 14.5 0.1 2.9 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KEZ41922.1 - 0.012 15.9 0.0 0.075 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KEZ41922.1 - 0.026 15.1 0.0 0.11 13.0 0.0 2.1 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KEZ41922.1 - 0.039 14.3 0.0 0.55 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 KEZ41922.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro_18 PF00704.28 KEZ41923.1 - 1.4e-47 162.9 0.1 1.2e-38 133.6 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.20 KEZ41924.1 - 7.1e-09 35.6 0.0 0.008 16.2 0.0 4.5 5 0 0 5 5 5 3 LysM domain Ank_4 PF13637.6 KEZ41925.1 - 3e-05 24.5 0.0 9.9e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ41925.1 - 0.012 16.1 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ41925.1 - 0.02 15.4 0.0 0.068 13.7 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 KEZ41925.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat DUF1771 PF08590.10 KEZ41925.1 - 0.14 12.6 0.1 0.41 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) LysM PF01476.20 KEZ41927.1 - 3.1e-26 91.2 0.0 6.8e-05 22.8 0.0 5.5 5 0 0 5 5 5 5 LysM domain HTH_Tnp_1 PF01527.20 KEZ41927.1 - 0.00089 19.5 0.0 18 5.7 0.0 3.9 4 0 0 4 4 4 2 Transposase Peptidase_C14 PF00656.22 KEZ41928.1 - 6.6e-05 23.0 0.0 0.00016 21.8 0.0 1.6 1 1 0 1 1 1 1 Caspase domain ubiquitin PF00240.23 KEZ41928.1 - 0.013 15.2 0.0 0.043 13.6 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin family TUG-UBL1 PF11470.8 KEZ41928.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 TUG ubiquitin-like domain UN_NPL4 PF11543.8 KEZ41928.1 - 0.068 13.7 0.0 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 CorA PF01544.18 KEZ41929.1 - 4e-07 29.6 1.2 1.1e-06 28.2 1.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein HALZ PF02183.18 KEZ41929.1 - 0.1 12.9 0.2 0.28 11.4 0.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper HATPase_c PF02518.26 KEZ41931.1 - 0.07 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 KEZ41932.1 - 1.7e-35 122.3 0.0 2.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41932.1 - 5.9e-25 88.2 0.0 8.7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41932.1 - 2.1e-08 34.3 0.0 3.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 KEZ41932.1 - 0.0037 16.9 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEZ41932.1 - 0.038 13.4 0.0 0.077 12.5 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ41932.1 - 0.061 12.7 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KEZ41933.1 - 3.4e-44 151.2 0.0 4.2e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ41933.1 - 3.6e-13 49.8 0.0 4.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KEZ41933.1 - 0.00017 22.0 0.2 0.0005 20.5 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEZ41933.1 - 0.00035 20.1 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEZ41933.1 - 0.0013 18.9 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.20 KEZ41933.1 - 0.015 15.4 0.3 0.032 14.4 0.3 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KEZ41933.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Chitin_synth_1 PF01644.17 KEZ41934.1 - 1.1e-67 227.1 0.0 1.7e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KEZ41934.1 - 2.6e-28 98.9 0.3 6.2e-24 84.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KEZ41934.1 - 1.2e-19 70.0 0.1 3.2e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KEZ41934.1 - 1e-09 38.6 6.5 8.5e-09 35.6 6.5 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 MARVEL PF01284.23 KEZ41935.1 - 0.00021 21.3 19.1 0.00083 19.4 19.1 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF2417 PF10329.9 KEZ41935.1 - 0.82 9.0 9.7 0.99 8.8 9.7 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) CTP_transf_1 PF01148.20 KEZ41935.1 - 0.9 9.2 8.8 1.1 9.0 8.8 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family DUF3938 PF13074.6 KEZ41935.1 - 1.2 9.5 8.9 0.2 11.9 5.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3938) DUF4293 PF14126.6 KEZ41935.1 - 1.8 8.8 10.5 4.1 7.7 10.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Tetraspanin PF00335.20 KEZ41935.1 - 3.2 7.4 10.1 5.3 6.7 10.1 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF2070 PF09843.9 KEZ41935.1 - 7 4.8 12.0 8.4 4.6 12.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FA_desaturase PF00487.24 KEZ41936.1 - 6.8e-28 98.2 22.2 1.1e-27 97.5 22.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3821 PF12863.7 KEZ41936.1 - 0.029 14.3 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) GST_N_2 PF13409.6 KEZ41937.1 - 1e-23 83.4 0.0 2e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ41937.1 - 4.8e-14 52.1 0.1 1.1e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEZ41937.1 - 2.2e-05 24.8 0.1 0.00038 20.8 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ41937.1 - 5e-05 23.4 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEZ41937.1 - 0.00014 22.0 0.0 0.00035 20.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CFEM PF05730.11 KEZ41938.1 - 0.0017 18.4 6.8 0.0017 18.4 6.8 2.0 2 1 0 2 2 2 1 CFEM domain p450 PF00067.22 KEZ41939.1 - 4.1e-45 154.4 0.0 5.2e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KEZ41940.1 - 1.8e-22 80.0 0.0 2.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41940.1 - 6.1e-13 49.3 0.0 2.6e-12 47.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ41940.1 - 4.2e-09 36.9 0.0 1.8e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41940.1 - 8.8e-08 32.1 0.0 6.7e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41940.1 - 3.1e-07 31.1 0.0 1.2e-06 29.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ41940.1 - 0.00014 21.4 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEZ41940.1 - 0.0008 19.6 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase D123 PF07065.14 KEZ41940.1 - 0.018 14.2 0.1 0.059 12.5 0.1 1.8 1 1 0 1 1 1 0 D123 PrmA PF06325.13 KEZ41940.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KEZ41940.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KEZ41940.1 - 0.15 11.3 0.0 0.73 9.1 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GMC_oxred_N PF00732.19 KEZ41941.1 - 1.6e-57 195.1 0.0 2.1e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ41941.1 - 1.6e-29 103.3 0.0 3.5e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KEZ41941.1 - 3.3e-05 23.2 0.0 7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KEZ41941.1 - 0.00032 20.9 0.0 0.0009 19.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ41941.1 - 0.00061 19.5 0.5 0.0014 18.3 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ41941.1 - 0.0024 17.1 0.1 0.29 10.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KEZ41941.1 - 0.0077 15.3 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DUF2284 PF10050.9 KEZ41942.1 - 0.026 14.3 38.6 0.67 9.7 1.9 4.8 5 0 0 5 5 5 0 Predicted metal-binding protein (DUF2284) Strep_his_triad PF04270.13 KEZ41942.1 - 1 9.4 17.4 43 4.2 0.1 5.2 5 0 0 5 5 5 0 Streptococcal histidine triad protein Pkinase_Tyr PF07714.17 KEZ41943.1 - 0.00071 18.9 0.0 0.0037 16.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEZ41943.1 - 0.00091 18.7 0.0 0.0036 16.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain PAX PF00292.18 KEZ41943.1 - 0.0011 18.9 0.1 0.025 14.5 0.0 2.8 3 0 0 3 3 3 1 'Paired box' domain Pkinase PF00069.25 KEZ41944.1 - 7.1e-41 140.3 0.0 1e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ41944.1 - 1.1e-18 67.5 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 KEZ41944.1 - 0.00041 19.9 1.5 0.0068 16.0 0.3 3.3 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 KEZ41944.1 - 0.00052 19.8 0.4 0.0023 17.8 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain Kdo PF06293.14 KEZ41944.1 - 0.015 14.6 0.0 0.045 13.1 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ41944.1 - 0.037 14.0 0.0 2 8.3 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3433 PF11915.8 KEZ41946.1 - 9.2e-17 61.3 29.0 3.1e-16 59.6 4.1 4.5 4 1 0 4 4 4 2 Protein of unknown function (DUF3433) CrgA PF06781.12 KEZ41946.1 - 0.55 10.3 2.1 28 4.9 0.1 2.5 2 0 0 2 2 2 0 Cell division protein CrgA SLC3A2_N PF16028.5 KEZ41946.1 - 4.8 6.8 5.3 5.9 6.5 3.5 2.1 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus Shikimate_dh_N PF08501.11 KEZ41947.1 - 1.5e-20 73.2 0.0 2.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KEZ41947.1 - 3.2e-05 23.6 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KEZ41947.1 - 0.035 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 KEZ41948.1 - 1.6e-136 455.8 23.6 1.8e-136 455.6 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ41948.1 - 3.9e-25 88.5 26.1 3.9e-25 88.5 26.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KEZ41949.1 - 1.7e-13 50.3 0.0 2.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ41950.1 - 4.7e-39 134.3 36.9 6.3e-39 133.9 36.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KEZ41950.1 - 0.007 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain OATP PF03137.20 KEZ41950.1 - 0.017 13.5 7.3 0.036 12.4 4.9 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DHquinase_I PF01487.15 KEZ41951.1 - 9.8e-25 88.1 0.0 2e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KEZ41951.1 - 1.5e-21 76.4 0.0 3.7e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KEZ41951.1 - 1.2e-10 40.9 0.4 2.3e-10 40.1 0.4 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain SKI PF01202.22 KEZ41951.1 - 1.5e-10 41.4 0.0 3.2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 KEZ41951.1 - 6e-09 36.1 0.1 1.6e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KEZ41951.1 - 0.012 16.1 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KEZ41951.1 - 0.026 13.5 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family adh_short PF00106.25 KEZ41951.1 - 0.084 12.3 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ41951.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KEZ41951.1 - 0.18 11.2 0.2 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 ThiF family cobW PF02492.19 KEZ41952.1 - 3.5e-48 163.5 7.2 3e-37 127.9 0.4 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KEZ41952.1 - 5.7e-17 61.4 0.1 2.4e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 KEZ41952.1 - 2.1e-06 26.9 0.4 0.0007 18.7 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 KEZ41952.1 - 0.0041 17.5 0.6 0.017 15.5 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.14 KEZ41952.1 - 0.0052 16.7 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KEZ41952.1 - 0.015 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KEZ41952.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.27 KEZ41952.1 - 0.029 13.9 2.3 1.3 8.5 0.5 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Serine_rich PF08824.10 KEZ41952.1 - 0.035 14.1 0.2 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain RsgA_GTPase PF03193.16 KEZ41952.1 - 0.043 13.7 0.7 10 6.0 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 KEZ41952.1 - 0.045 13.8 0.1 0.82 9.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEZ41952.1 - 0.047 13.9 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KEZ41952.1 - 0.093 12.5 0.1 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KEZ41952.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 KEZ41952.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 KEZ41952.1 - 0.16 11.8 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SHOCT PF09851.9 KEZ41952.1 - 0.27 11.0 2.8 29 4.6 0.1 3.8 3 0 0 3 3 3 0 Short C-terminal domain TFR_dimer PF04253.15 KEZ41953.1 - 4.1e-22 78.5 0.0 7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KEZ41953.1 - 2.6e-19 69.7 0.0 4.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEZ41953.1 - 1.6e-10 40.9 1.0 6.4e-10 38.9 1.1 2.1 2 1 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KEZ41953.1 - 0.0026 17.5 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Alpha-amylase PF00128.24 KEZ41954.1 - 5.3e-53 180.7 0.0 9.8e-53 179.9 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 KEZ41954.1 - 5.6e-27 93.5 0.2 1.2e-26 92.4 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 KEZ41954.1 - 4.8e-20 71.6 0.0 1.2e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) p450 PF00067.22 KEZ41955.1 - 1.3e-57 195.6 0.0 1.6e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KEZ41956.1 - 5.2e-49 166.9 0.7 7e-49 166.5 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ41956.1 - 1.6e-37 128.9 0.6 2.3e-37 128.4 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ41956.1 - 9.9e-09 35.4 0.1 1.4e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 KEZ41956.1 - 0.01 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus PALP PF00291.25 KEZ41956.1 - 0.013 15.0 0.9 0.016 14.6 0.9 1.3 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 KEZ41956.1 - 0.018 14.3 1.5 0.077 12.3 0.3 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 KEZ41956.1 - 0.052 13.4 0.4 0.083 12.8 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KEZ41956.1 - 0.085 12.9 1.7 0.16 12.0 1.8 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain G-alpha PF00503.20 KEZ41957.1 - 3.7e-55 187.5 0.0 2.1e-50 171.8 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KEZ41957.1 - 5.6e-12 45.4 0.1 1.2e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Helo_like_N PF17111.5 KEZ41957.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Gtr1_RagA PF04670.12 KEZ41957.1 - 0.0023 17.3 0.8 0.0071 15.7 0.0 2.1 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region PRANC PF09372.10 KEZ41957.1 - 0.11 12.9 0.3 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 PRANC domain Fungal_trans PF04082.18 KEZ41960.1 - 2.2e-13 49.9 0.7 4e-13 49.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ41961.1 - 1.1e-35 123.3 28.8 1.8e-35 122.5 28.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4863 PF16155.5 KEZ41962.1 - 2.5e-71 238.5 0.0 2.8e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) DUF1737 PF08410.10 KEZ41962.1 - 0.06 13.2 0.9 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) Pyr_redox_2 PF07992.14 KEZ41963.1 - 1.4e-13 50.8 0.0 7.9e-09 35.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KEZ41963.1 - 2.9e-11 42.5 0.0 1.2e-10 40.5 0.0 2.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ41963.1 - 1.6e-10 40.8 0.0 4.8e-08 32.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ41963.1 - 4.6e-10 39.2 0.0 7.5e-09 35.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEZ41963.1 - 2.5e-05 24.3 0.1 0.36 10.8 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEZ41963.1 - 3.7e-05 23.9 0.0 0.00012 22.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ41963.1 - 0.0053 16.4 0.1 16 4.9 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ41963.1 - 0.016 14.4 1.7 0.037 13.3 0.0 2.4 4 0 0 4 4 4 0 Thi4 family Lycopene_cycl PF05834.12 KEZ41963.1 - 0.019 14.0 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein B_lectin PF01453.24 KEZ41964.1 - 6.7e-06 26.6 0.1 7.7e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 D-mannose binding lectin Methylase_S PF01420.19 KEZ41964.1 - 0.18 12.0 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain Chitin_synth_1N PF08407.11 KEZ41965.1 - 7.8e-16 57.8 0.0 1.7e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal CRAL_TRIO PF00650.20 KEZ41965.1 - 0.17 11.6 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 CRAL/TRIO domain TRI12 PF06609.13 KEZ41966.1 - 2.3e-23 82.5 23.2 3.4e-23 81.9 23.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KEZ41966.1 - 7.8e-22 77.7 38.2 7.8e-22 77.7 38.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Glug PF07581.12 KEZ41966.1 - 1.3 9.6 5.2 0.71 10.4 2.0 2.4 2 0 0 2 2 2 0 The GLUG motif p450 PF00067.22 KEZ41967.1 - 2.2e-70 237.7 0.0 3.1e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cu-oxidase_2 PF07731.14 KEZ41968.1 - 1.3e-41 141.5 4.1 8.8e-40 135.6 0.1 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEZ41968.1 - 2e-37 127.8 2.1 2e-37 127.8 2.1 2.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KEZ41968.1 - 3.3e-34 118.3 0.2 8.9e-33 113.7 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase FliC PF12445.8 KEZ41969.1 - 0.015 15.6 1.0 0.027 14.8 1.0 1.4 1 1 0 1 1 1 0 Flagellin protein AMP-binding PF00501.28 KEZ41970.1 - 1.9e-78 263.9 0.0 2.5e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ41970.1 - 2.4e-12 47.6 0.0 9e-12 45.8 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3104 PF11302.8 KEZ41970.1 - 0.034 13.9 0.1 0.074 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Fungal_trans PF04082.18 KEZ41971.1 - 6.3e-15 54.9 0.3 9.9e-15 54.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3446 PF11928.8 KEZ41971.1 - 3 8.2 6.2 13 6.1 2.2 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Acyl-CoA_dh_1 PF00441.24 KEZ41972.1 - 2.5e-32 112.2 0.8 3.5e-32 111.7 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ41972.1 - 6.3e-24 84.0 0.2 1.1e-23 83.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEZ41972.1 - 1.2e-20 74.2 0.1 7e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEZ41972.1 - 0.028 14.7 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KEZ41972.1 - 0.24 11.0 0.5 0.72 9.5 0.5 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short PF00106.25 KEZ41973.1 - 4.2e-44 150.4 0.4 5.7e-44 149.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ41973.1 - 1.4e-42 145.9 1.1 6.7e-41 140.4 1.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ41973.1 - 8.3e-15 55.1 1.2 2.5e-14 53.6 1.2 1.7 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 KEZ41973.1 - 0.03 15.0 0.3 0.25 12.1 0.1 2.2 1 1 0 2 2 2 0 Methyltransferase domain Epimerase PF01370.21 KEZ41973.1 - 0.04 13.4 0.3 0.059 12.8 0.3 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEZ41973.1 - 0.045 14.0 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KEZ41973.1 - 0.059 13.6 0.6 0.11 12.8 0.6 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 KEZ41973.1 - 0.082 12.9 0.5 0.18 11.8 0.5 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ41973.1 - 0.1 12.0 0.3 0.17 11.2 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEZ41973.1 - 0.1 12.5 0.6 0.21 11.5 0.3 1.7 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 KEZ41974.1 - 2.6e-34 118.7 25.6 4.2e-34 118.0 25.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 KEZ41974.1 - 0.18 11.2 1.5 13 5.3 0.0 3.0 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family MFS_1 PF07690.16 KEZ41975.1 - 4e-33 114.8 42.2 4.4e-27 94.9 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM43 PF07787.12 KEZ41975.1 - 2.4 7.5 5.8 1.6 8.0 4.1 1.6 1 1 0 1 1 1 0 Transmembrane protein 43 MFS_1 PF07690.16 KEZ41976.1 - 5.5e-27 94.6 46.4 1.8e-21 76.5 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Yip1 PF04893.17 KEZ41977.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain Ank_2 PF12796.7 KEZ41978.1 - 3.3e-24 85.3 0.0 7.8e-11 42.4 0.0 5.2 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ41978.1 - 4e-14 52.5 5.1 1.2e-07 31.9 0.1 6.3 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ41978.1 - 2.1e-12 47.3 3.5 0.0034 17.9 0.0 7.0 6 2 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ41978.1 - 3.1e-12 45.5 1.9 0.039 14.5 0.0 7.0 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 KEZ41978.1 - 1.6e-11 44.1 1.3 0.0033 17.8 0.0 6.4 6 1 0 6 6 6 2 Ankyrin repeat NACHT PF05729.12 KEZ41978.1 - 6.5e-07 29.4 0.0 1.9e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 KEZ41978.1 - 0.00013 21.9 0.2 0.00034 20.6 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 KEZ41978.1 - 0.002 18.5 7.7 0.0038 17.6 0.0 4.2 4 1 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ41978.1 - 0.011 15.8 0.1 0.27 11.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Tex_N PF09371.10 KEZ41978.1 - 0.11 12.1 0.0 0.11 12.1 0.0 3.2 5 0 0 5 5 5 0 Tex-like protein N-terminal domain Y_phosphatase3 PF13350.6 KEZ41979.1 - 3.4e-51 174.5 0.0 3.8e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KEZ41979.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KEZ41979.1 - 0.022 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KEZ41979.1 - 0.19 11.6 0.0 0.28 11.0 0.0 1.4 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Sterol_MT_C PF08498.10 KEZ41980.1 - 1.1e-24 86.4 0.1 2.4e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KEZ41980.1 - 6.9e-23 81.1 0.0 1.6e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ41980.1 - 1.3e-22 80.3 0.0 2.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ41980.1 - 1.4e-20 73.6 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ41980.1 - 1.2e-15 57.5 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KEZ41980.1 - 2e-15 56.8 0.4 4.2e-15 55.8 0.1 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KEZ41980.1 - 4.6e-15 55.8 0.0 8.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ41980.1 - 3.5e-11 43.7 0.0 6.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ41980.1 - 6.4e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KEZ41980.1 - 1.6e-05 24.3 0.1 2.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_15 PF09445.10 KEZ41980.1 - 8.9e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KEZ41980.1 - 0.00013 21.4 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KEZ41980.1 - 0.00029 20.4 0.0 0.00058 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEZ41980.1 - 0.0019 18.4 0.1 0.0077 16.4 0.1 1.9 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KEZ41980.1 - 0.0028 17.7 0.4 0.0064 16.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 KEZ41980.1 - 0.0037 17.1 0.0 0.013 15.4 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.20 KEZ41980.1 - 0.005 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 KEZ41980.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 KEZ41980.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.26 KEZ41980.1 - 0.026 14.5 0.0 0.068 13.1 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.7 KEZ41980.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.16 KEZ41980.1 - 0.066 12.3 0.3 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 mRNA capping enzyme ADH_zinc_N_2 PF13602.6 KEZ41981.1 - 6.5e-11 43.4 0.0 1.1e-10 42.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ41981.1 - 3.6e-10 39.9 0.0 6.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ41981.1 - 2.3e-06 27.5 1.1 7.5e-05 22.6 0.7 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 KEZ41981.1 - 0.024 14.5 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding IBR PF01485.21 KEZ41982.1 - 6.7e-13 48.7 0.5 6.7e-13 48.7 0.5 5.4 6 2 0 6 6 6 2 IBR domain, a half RING-finger domain Ribosomal_S27e PF01667.17 KEZ41982.1 - 0.65 9.8 3.9 19 5.1 0.2 2.9 2 0 0 2 2 2 0 Ribosomal protein S27 Zn_ribbon_17 PF17120.5 KEZ41982.1 - 0.71 9.5 4.7 1.1 9.0 0.2 3.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Stathmin PF00836.19 KEZ41982.1 - 9.7 6.2 25.8 24 4.9 22.3 2.6 1 1 1 2 2 2 0 Stathmin family HHV-1_VABD PF16852.5 KEZ41983.1 - 1.2 9.2 4.1 6.6 6.8 0.3 2.5 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain Cupin_2 PF07883.11 KEZ41984.1 - 0.0053 16.4 1.5 0.056 13.2 0.5 2.5 2 1 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KEZ41984.1 - 0.035 13.7 0.1 0.044 13.4 0.1 1.2 1 0 0 1 1 1 0 Cupin Hpre_diP_synt_I PF07456.11 KEZ41985.1 - 0.06 13.4 0.4 0.06 13.4 0.4 2.0 2 1 1 3 3 3 0 Heptaprenyl diphosphate synthase component I RTA1 PF04479.13 KEZ41986.1 - 1.9e-62 210.6 11.4 2.7e-62 210.1 11.4 1.2 1 0 0 1 1 1 1 RTA1 like protein UL42 PF17638.2 KEZ41986.1 - 0.023 14.7 1.1 0.023 14.7 1.1 1.8 2 0 0 2 2 2 0 HCMV UL42 MFS_1 PF07690.16 KEZ41987.1 - 3.7e-26 91.9 27.1 4.1e-26 91.8 26.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ41987.1 - 4.6e-06 25.8 18.6 1.4e-05 24.2 9.1 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Fungal_trans_2 PF11951.8 KEZ41988.1 - 5.8e-05 22.1 0.2 0.00031 19.7 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ41988.1 - 0.027 14.6 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1290 PF06947.12 KEZ41988.1 - 0.16 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) ABC_transp_aux PF09822.9 KEZ41989.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Zn_clus PF00172.18 KEZ41990.1 - 0.00022 21.3 11.0 0.00039 20.5 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 KEZ41991.1 - 5.1e-21 75.2 0.4 2.6e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ41991.1 - 2.1e-10 40.8 0.1 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KEZ41991.1 - 2.5e-06 27.7 0.1 0.00018 21.7 0.1 2.6 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KEZ41991.1 - 0.028 14.5 0.1 1.3 9.1 0.0 3.0 3 1 0 3 3 3 0 Glyoxalase-like domain HgmA PF04209.13 KEZ41992.1 - 1.3e-193 643.5 0.0 1.9e-193 643.0 0.0 1.2 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PEP_mutase PF13714.6 KEZ41993.1 - 2.3e-51 174.5 0.1 2.9e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KEZ41993.1 - 8.8e-13 47.6 0.2 1.2e-12 47.1 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 KEZ41993.1 - 0.00026 20.5 0.2 0.072 12.5 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase MFS_1 PF07690.16 KEZ41994.1 - 6.1e-28 97.8 12.1 7.5e-28 97.5 12.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.6 KEZ41995.1 - 8.1e-12 45.3 5.9 1.5e-11 44.4 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEZ41995.1 - 5.2e-09 35.7 2.2 8.9e-09 34.9 2.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KEZ41995.1 - 2e-08 34.0 2.4 3.4e-08 33.3 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KEZ41995.1 - 5.7e-08 32.5 4.3 8.9e-08 31.9 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ41995.1 - 2.4e-07 30.5 4.6 4.8e-07 29.5 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KEZ41995.1 - 1.3e-05 24.9 2.1 2.3e-05 24.1 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ41995.1 - 2.3e-05 24.1 7.1 4.1e-05 23.3 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEZ41995.1 - 2.6e-05 24.4 6.3 8.7e-05 22.7 6.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KEZ41995.1 - 0.00049 20.1 3.8 0.00049 20.1 3.8 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KEZ41995.1 - 0.0092 16.0 2.2 0.021 14.8 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 KEZ41995.1 - 0.084 12.8 2.7 0.16 11.9 2.7 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KEZ41995.1 - 0.14 11.8 1.3 0.29 10.8 1.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type GAGA PF09237.11 KEZ41995.1 - 0.44 10.4 2.0 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 GAGA factor zf-RING_4 PF14570.6 KEZ41995.1 - 0.65 9.8 5.3 1.3 8.9 5.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 KEZ41995.1 - 1.1 9.3 5.3 4.7 7.3 5.3 2.1 1 1 0 1 1 1 0 Zinc-finger zf-C2H2 PF00096.26 KEZ41995.1 - 5.6 7.6 5.9 1.8 9.1 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type p450 PF00067.22 KEZ41996.1 - 1.1e-59 202.4 0.0 5.2e-57 193.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Amidohydro_2 PF04909.14 KEZ41997.1 - 4.3e-38 131.7 0.1 6.2e-38 131.2 0.1 1.3 1 1 0 1 1 1 1 Amidohydrolase FMN_dh PF01070.18 KEZ41998.1 - 8.5e-116 386.8 0.0 2.4e-115 385.3 0.0 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase AMP-binding PF00501.28 KEZ41998.1 - 6.2e-70 235.9 0.0 8.9e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ECH_1 PF00378.20 KEZ41998.1 - 5.8e-20 71.7 0.9 1.3e-08 34.5 0.1 3.1 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase Glu_synthase PF01645.17 KEZ41998.1 - 3.9e-05 23.0 0.2 7.1e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ECH_2 PF16113.5 KEZ41998.1 - 0.00014 21.5 0.1 0.036 13.6 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase NMO PF03060.15 KEZ41998.1 - 0.00014 21.4 0.5 0.00025 20.5 0.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KEZ41998.1 - 0.00058 19.0 1.3 0.0015 17.6 0.9 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KEZ41998.1 - 0.0013 18.1 0.1 0.17 11.2 0.1 2.6 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 KEZ41999.1 - 1.5e-19 70.2 33.5 3.2e-18 65.8 33.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KEZ41999.1 - 0.00065 18.1 6.4 0.15 10.3 0.5 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Pox_A14 PF05767.12 KEZ41999.1 - 0.0054 16.9 4.3 1.4 9.1 0.4 3.1 2 0 0 2 2 2 2 Poxvirus virion envelope protein A14 CrgA PF06781.12 KEZ41999.1 - 1.1 9.4 5.2 2.2 8.4 0.2 3.5 2 1 1 3 3 3 0 Cell division protein CrgA p450 PF00067.22 KEZ42000.1 - 1.6e-60 205.2 0.0 2e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RPE65 PF03055.15 KEZ42001.1 - 5.5e-90 302.8 0.0 7.6e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FAD_binding_4 PF01565.23 KEZ42001.1 - 3.3e-25 88.4 0.1 6.7e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ42001.1 - 0.00045 19.9 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Ribonuc_L-PSP PF01042.21 KEZ42002.1 - 1.1e-34 119.1 0.0 1.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_23 PF13489.6 KEZ42004.1 - 5.3e-15 55.7 0.0 7.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42004.1 - 1.4e-09 37.9 0.0 9.1e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42004.1 - 1.6e-09 38.4 0.0 3.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42004.1 - 1.8e-09 38.1 0.0 3.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42004.1 - 1.3e-06 29.1 0.0 3.5e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 KEZ42004.1 - 0.043 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 KEZ42004.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_N PF08240.12 KEZ42006.1 - 1.5e-26 92.4 2.9 2.4e-26 91.8 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KEZ42006.1 - 2.3e-12 46.9 0.0 1.2e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ42006.1 - 5.4e-12 45.3 0.0 7.9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 KEZ42006.1 - 9.8e-11 41.7 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 KEZ42006.1 - 3.2e-09 36.9 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEZ42006.1 - 3.3e-09 36.3 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KEZ42006.1 - 5.6e-06 26.0 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KEZ42006.1 - 8.2e-05 22.1 0.0 0.00074 19.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KEZ42006.1 - 0.00015 21.4 0.0 0.00037 20.1 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family 2-Hacid_dh_C PF02826.19 KEZ42006.1 - 0.0018 17.7 0.1 0.016 14.6 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KEZ42006.1 - 0.0046 16.1 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 KEZ42006.1 - 0.1 12.8 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 KEZ42006.1 - 0.22 11.4 3.2 0.15 11.9 0.2 2.1 2 1 0 2 2 2 0 KR domain Sugar_tr PF00083.24 KEZ42007.1 - 6e-104 348.4 13.0 7.3e-104 348.1 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42007.1 - 6.4e-27 94.4 27.3 3.3e-22 78.9 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 KEZ42008.1 - 1.1e-09 38.2 9.6 2.3e-09 37.2 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ42008.1 - 0.0029 16.7 0.3 0.28 10.2 0.0 2.6 1 1 1 2 2 2 2 Fungal specific transcription factor domain MR_MLE_C PF13378.6 KEZ42009.1 - 1.8e-50 171.5 0.0 2.9e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEZ42009.1 - 0.0016 18.6 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KEZ42009.1 - 0.057 12.6 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus EI24 PF07264.11 KEZ42010.1 - 0.013 15.8 0.7 0.037 14.3 0.1 2.0 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF202 PF02656.15 KEZ42010.1 - 2.5 8.6 4.7 6.6 7.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Peptidase_M24 PF00557.24 KEZ42011.1 - 6.5e-37 127.3 0.0 8.4e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_23 PF13489.6 KEZ42012.1 - 1.5e-13 50.9 0.0 2.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42012.1 - 8.4e-06 26.4 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42012.1 - 1.5e-05 25.6 0.0 4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42012.1 - 0.0019 18.9 0.0 0.0091 16.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42012.1 - 0.062 13.1 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.25 KEZ42013.1 - 9.4e-09 35.0 0.0 3.1e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ42013.1 - 6.5e-05 22.9 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 KR domain HET PF06985.11 KEZ42014.1 - 7.6e-23 81.5 0.0 1.4e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Scm3 PF10384.9 KEZ42014.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Centromere protein Scm3 zf-C2H2_4 PF13894.6 KEZ42015.1 - 9.8e-08 32.2 9.5 0.017 15.9 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ42015.1 - 1.6e-06 28.2 10.4 0.11 13.0 1.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KEZ42015.1 - 1.3e-05 25.5 5.2 0.0074 16.6 0.7 2.8 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEZ42015.1 - 4.7e-05 23.6 8.2 0.011 16.0 0.7 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KEZ42015.1 - 0.00019 21.7 5.2 0.47 11.0 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain Rad50_zn_hook PF04423.14 KEZ42015.1 - 0.0015 18.3 0.7 2.1 8.2 0.1 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 KEZ42015.1 - 0.0046 17.0 8.2 0.099 12.8 0.3 3.6 3 1 1 4 4 4 1 Zinc ribbon domain zf-C2HC_2 PF13913.6 KEZ42015.1 - 0.0052 16.6 3.6 1.4 8.9 0.2 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Prok-RING_4 PF14447.6 KEZ42015.1 - 0.0056 16.5 0.2 0.61 10.0 0.1 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-met PF12874.7 KEZ42015.1 - 0.012 16.0 10.4 0.31 11.5 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-DNA_Pol PF08996.10 KEZ42015.1 - 0.023 14.5 1.1 0.052 13.3 0.2 1.8 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF1360 PF07098.11 KEZ42015.1 - 0.03 14.3 0.0 4.9 7.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1360) zf-Di19 PF05605.12 KEZ42015.1 - 0.046 14.0 9.6 0.42 11.0 0.3 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KEZ42015.1 - 0.057 13.4 1.0 0.057 13.4 1.0 2.7 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KEZ42015.1 - 0.13 12.1 5.1 5.1 7.0 0.2 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_9 PF14369.6 KEZ42015.1 - 0.19 12.0 7.0 0.25 11.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon DUF2024 PF09630.10 KEZ42015.1 - 0.24 11.3 0.7 9.4 6.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) zinc-ribbons_6 PF07191.12 KEZ42015.1 - 0.29 11.1 2.5 18 5.4 0.1 2.9 2 1 1 3 3 3 0 zinc-ribbons UBZ_FAAP20 PF15750.5 KEZ42015.1 - 0.46 10.5 2.8 1.3 9.0 0.5 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger AKAP95 PF04988.12 KEZ42015.1 - 3.1 8.0 6.7 0.74 10.0 1.0 2.4 3 0 0 3 3 2 0 A-kinase anchoring protein 95 (AKAP95) HET PF06985.11 KEZ42016.1 - 5.6e-30 104.6 0.0 8.1e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC2_membrane PF01061.24 KEZ42017.1 - 3.7e-88 294.4 55.5 9.2e-46 155.9 23.7 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KEZ42017.1 - 2e-36 123.8 0.8 4.6e-33 113.0 0.1 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KEZ42017.1 - 2.5e-34 118.7 0.0 1.1e-15 58.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KEZ42017.1 - 3.9e-15 56.2 0.2 1.3e-14 54.6 0.2 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KEZ42017.1 - 1.6e-06 27.8 0.1 4.6e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ42017.1 - 3.8e-06 27.4 0.6 0.00045 20.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KEZ42017.1 - 0.00011 22.3 0.1 0.18 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KEZ42017.1 - 0.00048 20.1 0.1 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KEZ42017.1 - 0.00062 19.7 0.2 1.4 8.6 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KEZ42017.1 - 0.0013 19.3 0.1 0.06 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ42017.1 - 0.0019 18.0 0.8 0.14 11.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEZ42017.1 - 0.0022 18.4 0.0 0.42 11.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KEZ42017.1 - 0.003 17.2 0.8 0.13 11.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KEZ42017.1 - 0.0037 17.5 0.1 0.74 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ42017.1 - 0.004 16.8 0.4 0.036 13.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KEZ42017.1 - 0.013 15.5 0.3 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 KEZ42017.1 - 0.039 13.4 0.0 5.7 6.3 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KEZ42017.1 - 0.084 13.3 0.3 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEZ42017.1 - 0.092 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KEZ42017.1 - 0.096 12.4 0.2 15 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEZ42017.1 - 0.8 9.9 2.7 4.8 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Peptidase_M20 PF01546.28 KEZ42019.1 - 9.1e-19 68.0 0.2 6.6e-18 65.2 0.2 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ42019.1 - 8.1e-18 64.3 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEZ42019.1 - 1.4e-05 24.8 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 YchF-GTPase_C PF06071.13 KEZ42020.1 - 3.5e-38 129.7 0.0 1e-37 128.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KEZ42020.1 - 3.2e-10 40.1 0.0 7.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase p450 PF00067.22 KEZ42021.1 - 0.052 12.3 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 adh_short_C2 PF13561.6 KEZ42022.1 - 3.8e-60 203.4 0.0 4.7e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ42022.1 - 1.3e-45 155.3 0.0 1.6e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ42022.1 - 6.5e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ42022.1 - 0.00049 19.3 0.0 0.00071 18.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEZ42022.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 KEZ42023.1 - 6.5e-26 91.5 0.0 9e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEZ42023.1 - 1.4e-15 57.0 0.0 2.1e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Aconitase PF00330.20 KEZ42023.1 - 0.00028 20.0 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF2974 PF11187.8 KEZ42023.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 KEZ42023.1 - 0.047 13.0 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEZ42023.1 - 0.08 12.4 0.0 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.25 KEZ42024.1 - 1.5e-32 112.6 0.0 2.2e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ42024.1 - 2.4e-29 102.6 0.0 3.2e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ42024.1 - 0.00023 21.1 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short PF00106.25 KEZ42025.1 - 1.9e-42 145.0 0.1 2.6e-42 144.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ42025.1 - 7.5e-33 114.0 0.0 9.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ42025.1 - 1.3e-06 28.5 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ42025.1 - 0.00054 19.5 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 KEZ42025.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KEZ42025.1 - 0.2 11.2 1.0 3.1 7.3 0.2 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MFS_1 PF07690.16 KEZ42026.1 - 1.7e-25 89.7 18.9 1.7e-25 89.7 18.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ42026.1 - 5.7e-05 22.2 26.4 0.00048 19.1 26.3 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1616 PF07760.11 KEZ42026.1 - 0.14 11.5 1.4 0.32 10.3 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) CBM_20 PF00686.19 KEZ42028.1 - 1.8e-34 117.5 0.7 3.1e-34 116.8 0.7 1.4 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KEZ42028.1 - 3.1e-08 34.5 6.9 7.5e-08 33.3 6.9 1.7 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 KEZ42028.1 - 0.0045 16.9 0.8 0.008 16.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Fungal_lectin PF07938.12 KEZ42029.1 - 1.3e-08 34.7 2.5 0.00061 19.3 0.0 2.4 2 1 0 2 2 2 2 Fungal fucose-specific lectin Glyco_hydro_18 PF00704.28 KEZ42030.1 - 6e-89 298.9 4.2 6.9e-89 298.6 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HET PF06985.11 KEZ42031.1 - 1.3e-34 119.6 0.7 3.2e-34 118.4 0.7 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nuc_deoxyri_tr2 PF15891.5 KEZ42031.1 - 0.022 15.1 0.1 0.069 13.5 0.0 1.9 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Epimerase PF01370.21 KEZ42032.1 - 5.9e-09 35.7 0.0 0.00042 19.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ42032.1 - 0.00016 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KEZ42032.1 - 0.00022 21.6 0.0 0.00048 20.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KEZ42032.1 - 0.00031 20.7 0.1 0.00075 19.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEZ42032.1 - 0.0097 15.1 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KEZ42032.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 KEZ42034.1 - 1.9e-48 165.4 0.0 2.6e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KEZ42035.1 - 8.5e-26 90.8 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42035.1 - 9.9e-13 48.6 0.0 2.6e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42035.1 - 3e-10 40.1 0.0 3.9e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42035.1 - 4.8e-10 40.0 0.0 8.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42035.1 - 2.7e-09 37.7 0.0 1.4e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KEZ42035.1 - 8.9e-05 22.7 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ42035.1 - 0.0028 17.2 0.0 0.0097 15.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ42035.1 - 0.0032 17.0 0.0 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KEZ42035.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KEZ42035.1 - 0.053 12.8 0.0 0.38 10.0 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0146 PF03686.13 KEZ42035.1 - 0.14 12.1 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Methyltransf_PK PF05891.12 KEZ42035.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Inhibitor_I36 PF03995.13 KEZ42036.1 - 0.0092 15.9 4.8 0.02 14.8 4.8 1.5 1 1 0 1 1 1 1 Peptidase inhibitor family I36 Ldl_recept_b PF00058.17 KEZ42036.1 - 0.047 14.2 7.2 1.2 9.7 0.2 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B Fungal_trans_2 PF11951.8 KEZ42037.1 - 0.0004 19.3 0.0 0.00067 18.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.28 KEZ42038.1 - 5.4e-42 144.6 3.4 8.8e-42 143.9 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KEZ42038.1 - 2.1e-08 34.1 0.1 0.00093 19.2 0.3 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KEZ42038.1 - 6.5e-06 26.5 7.2 6.5e-06 26.5 7.2 3.5 3 1 0 3 3 3 1 Chitin recognition protein BNIP2 PF12496.8 KEZ42038.1 - 0.1 13.0 0.1 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF3659 PF12396.8 KEZ42039.1 - 1e-114 374.4 53.9 1.4e-22 79.4 3.4 6.5 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 KEZ42039.1 - 0.00061 19.7 0.7 0.71 9.8 0.0 3.9 4 0 0 4 4 4 2 Glycine cleavage T-protein C-terminal barrel domain 2C_adapt PF08793.10 KEZ42039.1 - 0.042 14.0 0.1 0.64 10.2 0.0 3.0 3 0 0 3 3 3 0 2-cysteine adaptor domain Pilosulin PF17499.2 KEZ42039.1 - 2 8.6 3.9 5.6 7.2 0.3 3.2 2 0 0 2 2 2 0 Ant venom peptides HNH_2 PF13391.6 KEZ42040.1 - 2.4e-12 46.8 0.0 4.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Carb_bind PF10645.9 KEZ42041.1 - 2.6e-15 56.3 4.5 2.6e-15 56.3 4.5 2.4 3 0 0 3 3 3 1 Carbohydrate binding Sugar_tr PF00083.24 KEZ42044.1 - 3.8e-91 306.2 25.2 9.7e-51 173.0 2.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42044.1 - 4.7e-09 35.6 34.9 1.7e-06 27.2 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phospholip_A2_3 PF09056.11 KEZ42045.1 - 3.7e-46 156.3 0.1 4.8e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 TetR_C_11 PF16859.5 KEZ42045.1 - 0.1 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Clr5 PF14420.6 KEZ42046.1 - 1.9e-14 53.6 1.3 4e-14 52.6 1.3 1.6 1 0 0 1 1 1 1 Clr5 domain GFA PF04828.14 KEZ42047.1 - 3.8e-05 23.9 0.0 3.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KEZ42047.1 - 0.0068 16.1 0.1 0.0068 16.1 0.1 2.2 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain SnoaL_2 PF12680.7 KEZ42048.1 - 2.9e-06 27.8 0.4 3.9e-06 27.4 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KEZ42048.1 - 0.00016 22.0 0.3 0.00037 20.8 0.4 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 KEZ42048.1 - 0.045 14.0 0.1 0.069 13.4 0.1 1.5 1 1 1 2 2 2 0 SnoaL-like domain Hydrolase_4 PF12146.8 KEZ42049.1 - 4.8e-23 81.7 0.1 3.2e-22 79.0 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ42049.1 - 2.5e-18 66.6 0.1 9.7e-15 54.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ42049.1 - 7.8e-18 65.9 0.0 9.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KEZ42049.1 - 8.4e-11 42.4 0.1 1.5e-10 41.6 0.1 1.3 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 KEZ42049.1 - 2.8e-06 27.0 0.0 0.053 13.0 0.0 2.5 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 KEZ42049.1 - 4.1e-05 23.2 0.1 0.26 10.8 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.13 KEZ42049.1 - 8.2e-05 22.5 0.0 0.007 16.2 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase DUF676 PF05057.14 KEZ42049.1 - 0.00017 21.2 0.2 0.00027 20.5 0.2 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 KEZ42049.1 - 0.00019 21.2 0.1 0.0035 17.1 0.1 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEZ42049.1 - 0.00029 20.8 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KEZ42049.1 - 0.00088 19.1 0.3 0.12 12.2 0.0 2.9 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KEZ42049.1 - 0.0012 18.6 0.1 0.0014 18.3 0.1 1.3 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 KEZ42049.1 - 0.0013 18.5 1.3 0.0045 16.7 1.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.11 KEZ42049.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 KEZ42049.1 - 0.0022 17.0 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 KEZ42049.1 - 0.0051 16.7 0.2 0.0094 15.8 0.2 1.4 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.13 KEZ42049.1 - 0.0054 16.4 0.0 0.055 13.1 0.0 2.4 1 1 1 2 2 2 1 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 KEZ42049.1 - 0.013 15.1 0.1 0.056 13.0 0.1 1.9 2 1 0 2 2 2 0 Lipid-droplet associated hydrolase PAF-AH_p_II PF03403.13 KEZ42049.1 - 0.029 12.9 1.6 1.6 7.1 0.3 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Palm_thioest PF02089.15 KEZ42049.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Chlorophyllase PF07224.11 KEZ42049.1 - 0.053 12.5 0.1 0.077 12.0 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase AXE1 PF05448.12 KEZ42049.1 - 0.067 11.8 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF1057 PF06342.12 KEZ42049.1 - 0.089 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) MFS_1 PF07690.16 KEZ42050.1 - 6.5e-22 77.9 52.0 3.6e-11 42.6 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEZ42050.1 - 0.43 9.1 29.2 0.014 14.0 13.3 3.2 1 1 0 2 2 2 0 MFS/sugar transport protein TraQ PF09679.10 KEZ42050.1 - 1.9 8.4 4.3 0.79 9.7 0.3 2.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DJ-1_PfpI PF01965.24 KEZ42051.1 - 9.3e-16 58.1 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 KEZ42051.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Transp_cyt_pur PF02133.15 KEZ42052.1 - 5.1e-61 206.8 26.1 5.8e-61 206.6 26.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AltA1 PF16541.5 KEZ42053.1 - 0.0072 17.2 2.9 2 9.3 0.1 2.8 2 2 0 2 2 2 2 Alternaria alternata allergen 1 AltA1 PF16541.5 KEZ42054.1 - 1e-05 26.3 2.3 0.0044 17.9 1.3 2.8 3 1 0 3 3 3 2 Alternaria alternata allergen 1 DUF5508 PF17621.2 KEZ42054.1 - 0.079 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5508) p450 PF00067.22 KEZ42055.1 - 2.9e-71 240.6 0.0 4.4e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KEZ42055.1 - 4.2e-29 101.7 0.0 9.7e-29 100.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 KEZ42055.1 - 5.7e-25 88.2 0.0 1.2e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEZ42055.1 - 1.9e-11 44.6 0.0 4.7e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KEZ42055.1 - 0.012 15.9 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain NAD_binding_6 PF08030.12 KEZ42055.1 - 0.2 11.8 0.1 13 5.9 0.4 2.8 3 0 0 3 3 3 0 Ferric reductase NAD binding domain adh_short PF00106.25 KEZ42056.1 - 3.6e-31 108.2 1.4 5.2e-22 78.3 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ42056.1 - 4.7e-24 85.2 1.0 5.2e-22 78.5 1.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ42056.1 - 1.5e-05 25.0 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KEZ42056.1 - 0.057 12.8 0.0 0.57 9.5 0.0 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Enoyl_reductase PF12241.8 KEZ42056.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Sod_Fe_C PF02777.18 KEZ42057.1 - 8.7e-36 122.2 0.1 1.6e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEZ42057.1 - 3.9e-34 117.0 2.5 6.1e-34 116.3 0.8 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GATase_5 PF13507.6 KEZ42059.1 - 3.6e-100 334.4 0.0 5.5e-100 333.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KEZ42059.1 - 4.7e-37 127.5 0.4 2.5e-24 86.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KEZ42059.1 - 3.6e-23 81.8 0.0 6.9e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KEZ42059.1 - 8.9e-21 74.2 0.0 2.5e-20 72.8 0.0 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Zn_clus PF00172.18 KEZ42060.1 - 6.4e-13 48.6 28.4 1.4e-06 28.3 7.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ42060.1 - 2.5e-06 26.7 1.0 4.7e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain NmrA PF05368.13 KEZ42061.1 - 4.2e-32 111.6 0.0 8e-32 110.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ42061.1 - 1.1e-11 45.0 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEZ42061.1 - 0.001 19.4 0.0 0.0023 18.2 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 KEZ42061.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KEZ42061.1 - 0.0056 16.2 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KEZ42061.1 - 0.033 14.8 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_23 PF13489.6 KEZ42062.1 - 2.8e-20 72.8 0.4 4.6e-20 72.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42062.1 - 9.9e-12 44.9 0.0 1.8e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42062.1 - 1.1e-10 42.1 0.0 3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42062.1 - 9.1e-07 29.4 0.0 2.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42062.1 - 2.1e-05 25.2 0.0 0.0001 22.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ42062.1 - 0.0046 16.4 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KEZ42062.1 - 0.0062 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KEZ42062.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEZ42062.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 KEZ42062.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KEZ42062.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain DUF4661 PF15576.6 KEZ42062.1 - 0.3 11.0 1.5 0.53 10.1 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Glyco_hydro_12 PF01670.16 KEZ42063.1 - 4.7e-12 46.3 0.0 5.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF3624 PF12292.8 KEZ42063.1 - 0.34 11.4 1.2 0.85 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3624) WD40 PF00400.32 KEZ42064.1 - 3.5e-12 46.6 7.1 0.026 15.4 0.0 8.0 8 0 0 8 8 8 2 WD domain, G-beta repeat NACHT PF05729.12 KEZ42064.1 - 4.6e-09 36.4 0.1 9.7e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KEZ42064.1 - 0.002 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) ANAPC4_WD40 PF12894.7 KEZ42064.1 - 0.0033 17.7 0.1 7.8 6.9 0.0 3.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 KEZ42064.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 KEZ42064.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2713 PF10897.8 KEZ42065.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Glyco_hydro_63 PF03200.16 KEZ42066.1 - 2.1e-75 254.4 0.0 8.4e-47 160.0 0.0 3.2 1 1 2 3 3 3 3 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KEZ42066.1 - 3.7e-46 158.0 0.0 5.4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Ank_4 PF13637.6 KEZ42066.1 - 0.0005 20.6 0.1 0.0033 18.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ammonium_transp PF00909.21 KEZ42066.1 - 0.079 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Ammonium Transporter Family MFS_1 PF07690.16 KEZ42067.1 - 1.8e-05 23.8 9.7 0.00025 20.1 9.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 KEZ42067.1 - 0.081 12.8 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 VIT family SpoIIM PF01944.17 KEZ42067.1 - 0.58 10.2 8.6 0.98 9.4 8.5 1.5 1 1 0 1 1 1 0 Stage II sporulation protein M Fungal_trans PF04082.18 KEZ42068.1 - 5.7e-19 68.2 0.0 9.3e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42068.1 - 2.6e-07 30.6 9.7 5.1e-07 29.7 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 KEZ42069.1 - 1.1e-44 153.2 0.0 1.6e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ42069.1 - 3.6e-14 53.1 0.0 1.9e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.18 KEZ42069.1 - 5.6e-14 51.8 0.8 9.3e-14 51.1 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42069.1 - 1.2e-06 28.5 9.9 2.8e-06 27.3 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEZ42070.1 - 1.5e-30 106.3 32.0 1.9e-30 106.0 32.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Iso_dh PF00180.20 KEZ42071.1 - 1.9e-84 283.8 0.0 2.3e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aldedh PF00171.22 KEZ42072.1 - 5.8e-150 499.8 0.0 6.7e-150 499.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ42072.1 - 0.023 14.1 0.1 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Aminotran_3 PF00202.21 KEZ42073.1 - 2.9e-117 391.8 0.0 3.3e-117 391.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.16 KEZ42075.1 - 9.3e-30 103.7 35.7 4e-29 101.6 31.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyoxalase PF00903.25 KEZ42076.1 - 5.6e-14 52.4 1.6 4.9e-11 42.9 0.7 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ42076.1 - 0.00029 21.1 0.1 0.0011 19.2 0.1 2.0 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_N PF08240.12 KEZ42077.1 - 3e-20 72.1 0.3 4.8e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ42077.1 - 9.7e-20 70.9 1.0 4.4e-19 68.8 0.1 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ42077.1 - 7.2e-06 25.6 0.9 1.1e-05 25.0 0.9 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEZ42077.1 - 2.3e-05 25.4 0.1 4.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Gp_dh_N PF00044.24 KEZ42077.1 - 0.031 14.6 0.2 0.2 12.0 0.0 2.0 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KEZ42077.1 - 0.057 14.1 0.8 0.12 13.1 0.8 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain PEP-CTERM PF07589.11 KEZ42077.1 - 0.13 12.4 0.8 0.42 10.8 0.8 1.9 1 0 0 1 1 1 0 PEP-CTERM motif Aldedh PF00171.22 KEZ42078.1 - 2.2e-139 464.9 0.0 2.8e-139 464.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_S15 PF02129.18 KEZ42079.1 - 1.4e-42 146.1 1.3 2.4e-42 145.4 1.3 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KEZ42079.1 - 2.1e-38 132.5 0.2 4e-38 131.6 0.2 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 KEZ42079.1 - 0.037 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 KEZ42080.1 - 1e-86 291.3 0.0 1.4e-86 290.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ42080.1 - 0.012 14.9 0.1 0.026 13.7 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ42080.1 - 0.096 12.9 0.1 0.37 11.0 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ42080.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KEZ42081.1 - 2.5e-15 56.6 0.1 2e-14 53.6 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ42081.1 - 4.7e-10 39.6 1.9 5.2e-05 23.0 1.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ42081.1 - 1.2e-06 28.7 0.1 6e-06 26.4 0.1 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEZ42081.1 - 1.6e-06 27.3 0.0 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KEZ42081.1 - 2.2e-06 27.7 0.6 0.0051 16.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ42081.1 - 3.1e-06 26.5 1.0 1.4e-05 24.4 1.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEZ42081.1 - 2.1e-05 23.9 0.9 0.0011 18.3 0.3 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ42081.1 - 4.2e-05 22.8 0.6 0.0001 21.5 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KEZ42081.1 - 0.00035 21.1 0.3 0.0016 19.0 0.2 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ42081.1 - 0.0011 18.2 0.3 0.0019 17.5 0.3 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KEZ42081.1 - 0.0013 17.5 0.2 0.016 14.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ42081.1 - 0.013 14.7 0.5 0.021 14.1 0.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ42081.1 - 0.058 12.7 0.4 0.1 11.9 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.22 KEZ42082.1 - 7.2e-57 193.1 0.0 1.7e-52 178.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Plasmo_rep PF12135.8 KEZ42082.1 - 0.085 12.4 0.2 0.21 11.2 0.2 1.7 1 0 0 1 1 1 0 Plasmodium repeat family FAD_binding_3 PF01494.19 KEZ42083.1 - 3.6e-20 72.5 0.5 7.6e-20 71.4 0.5 1.4 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 KEZ42083.1 - 5.8e-12 45.7 0.0 8.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 KEZ42083.1 - 1.6e-06 27.6 0.1 3.1e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ42083.1 - 5.3e-06 26.6 0.2 1.5e-05 25.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ42083.1 - 7.9e-06 25.2 0.2 1.6e-05 24.2 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KEZ42083.1 - 6.8e-05 22.6 3.0 0.00016 21.4 2.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ42083.1 - 0.0033 16.7 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ42083.1 - 0.005 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KEZ42083.1 - 0.0072 15.4 0.0 0.88 8.5 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 KEZ42083.1 - 0.0075 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KEZ42083.1 - 0.022 13.6 0.9 0.066 12.0 0.5 1.8 1 1 1 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KEZ42083.1 - 0.026 13.8 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 KEZ42083.1 - 0.026 13.3 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pyr_redox PF00070.27 KEZ42083.1 - 0.036 14.6 0.1 0.11 13.0 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ42083.1 - 0.091 12.0 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AMP-binding PF00501.28 KEZ42085.1 - 0 1278.0 0.0 1.4e-69 234.7 0.0 7.2 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 KEZ42085.1 - 0 1125.4 0.0 8.5e-81 271.9 0.0 9.5 9 1 0 9 9 9 9 Condensation domain PP-binding PF00550.25 KEZ42085.1 - 1.1e-78 259.5 2.9 1e-12 48.2 0.0 7.2 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ42085.1 - 2.4e-22 79.7 0.0 1.1e-08 35.9 0.0 4.9 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain AntA PF08346.12 KEZ42085.1 - 0.12 13.0 0.1 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 AntA/AntB antirepressor VCBS PF13517.6 KEZ42086.1 - 5.7e-33 113.3 53.6 1.5e-12 47.9 1.1 7.5 2 2 5 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KEZ42086.1 - 8.6e-14 52.3 0.3 1.9e-13 51.2 0.3 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ42086.1 - 6.3e-08 32.8 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 KEZ42086.1 - 5e-05 23.3 32.4 0.013 15.6 0.2 6.7 6 0 0 6 6 6 3 FG-GAP repeat Lipase_GDSL_3 PF14606.6 KEZ42086.1 - 0.00027 21.1 0.0 0.0025 18.0 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 KEZ42086.1 - 0.00058 19.3 6.8 1.9 7.8 0.0 5.9 5 1 1 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region EnY2 PF10163.9 KEZ42086.1 - 0.22 11.9 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Transcription factor e(y)2 Dockerin_1 PF00404.18 KEZ42086.1 - 0.95 9.7 15.5 3.5 7.9 0.0 5.6 6 0 0 6 6 6 0 Dockerin type I domain Abhydrolase_3 PF07859.13 KEZ42087.1 - 6e-40 137.4 0.0 7.5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ42087.1 - 0.00084 18.7 0.0 1.1 8.4 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KEZ42087.1 - 0.006 16.2 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KEZ42087.1 - 0.04 13.4 0.0 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family SHMT PF00464.19 KEZ42088.1 - 1.8e-199 662.3 0.0 2.1e-199 662.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 KEZ42088.1 - 0.049 12.9 0.0 0.098 11.9 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KEZ42088.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.25 KEZ42089.1 - 4.9e-35 120.8 0.0 6.8e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ42089.1 - 2.4e-19 69.9 0.0 3.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ42089.1 - 8.2e-07 29.1 0.0 4.4e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ42089.1 - 3.9e-05 23.2 0.0 0.00023 20.7 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ42089.1 - 0.00037 19.6 0.0 0.00055 19.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.19 KEZ42090.1 - 9.4e-77 258.6 0.0 1.2e-76 258.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEZ42090.1 - 2.2e-37 128.7 0.0 3.6e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KEZ42090.1 - 0.00019 20.7 0.2 0.001 18.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KEZ42090.1 - 0.0026 17.4 2.5 0.033 13.8 0.7 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEZ42090.1 - 0.0037 16.7 0.4 0.0083 15.5 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ42090.1 - 0.004 16.4 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KEZ42090.1 - 0.0057 15.8 0.0 0.019 14.0 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KEZ42090.1 - 0.026 13.8 0.0 0.051 12.8 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ42090.1 - 0.059 12.6 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ42090.1 - 0.064 13.5 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Arylsulfotran_2 PF14269.6 KEZ42091.1 - 6e-54 183.4 0.1 3.9e-52 177.5 0.1 2.3 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KEZ42091.1 - 5.3e-20 71.7 0.1 5.7e-19 68.3 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) AMP-binding PF00501.28 KEZ42092.1 - 1.2e-64 218.5 0.0 5.9e-35 120.7 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ42092.1 - 3.6e-05 24.6 0.0 0.00012 22.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_79C PF16862.5 KEZ42093.1 - 7.6e-24 84.6 0.1 1.9e-23 83.3 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Sulfatase PF00884.23 KEZ42094.1 - 1.2e-74 251.5 0.0 1.5e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KEZ42094.1 - 0.0091 14.6 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 KEZ42094.1 - 0.019 14.6 0.0 0.08 12.5 0.0 1.9 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase PLA2G12 PF06951.11 KEZ42094.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) SOG2 PF10428.9 KEZ42095.1 - 0.095 11.9 3.4 0.11 11.7 3.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sugar_tr PF00083.24 KEZ42096.1 - 1.4e-98 330.7 20.6 1.6e-98 330.5 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42096.1 - 2.3e-14 53.1 25.6 2.3e-14 53.1 25.6 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 KEZ42097.1 - 1e-36 126.6 46.7 4e-28 98.4 25.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ42097.1 - 3.1e-06 26.3 17.1 6.9e-05 21.9 3.0 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KEZ42097.1 - 3.5e-06 25.8 21.5 0.0017 17.0 4.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 KEZ42097.1 - 0.19 10.5 23.6 0.0072 15.2 8.8 3.3 2 1 1 3 3 3 0 Sugar (and other) transporter OATP PF03137.20 KEZ42097.1 - 1.5 7.0 8.5 1.9 6.7 1.8 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MR_MLE_C PF13378.6 KEZ42098.1 - 2e-54 184.5 0.0 3.1e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEZ42098.1 - 7.6e-23 81.0 0.0 1.6e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MFS_1 PF07690.16 KEZ42099.1 - 2.8e-28 98.9 41.3 2e-19 69.8 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ42099.1 - 0.00012 20.7 2.1 0.00085 17.9 0.2 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_10 PF00331.20 KEZ42100.1 - 3e-82 276.3 0.1 3.7e-82 276.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Lipase_GDSL PF00657.22 KEZ42100.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Glyco_hydro_3 PF00933.21 KEZ42101.1 - 2.4e-23 83.0 0.0 7.8e-20 71.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEZ42101.1 - 1.2e-16 61.3 0.0 3.6e-12 46.7 0.0 2.9 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Sugar_tr PF00083.24 KEZ42102.1 - 1.6e-86 291.0 18.5 1.9e-86 290.7 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42102.1 - 5.7e-23 81.4 31.3 8.7e-17 61.1 9.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEZ42102.1 - 0.13 10.6 5.2 0.91 7.7 0.6 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 KEZ42102.1 - 0.45 9.3 12.4 0.022 13.6 2.6 2.3 2 0 0 2 2 2 0 POT family DUF5597 PF18120.1 KEZ42103.1 - 7.1e-25 87.7 0.0 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 KEZ42103.1 - 1.5e-09 37.7 0.1 3.2e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 KEZ42103.1 - 0.0001 22.1 0.0 0.00034 20.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 HTH_21 PF13276.6 KEZ42103.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain Glyco_hydro_1 PF00232.18 KEZ42104.1 - 1.3e-15 56.8 0.0 4e-07 28.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 GP120 PF00516.18 KEZ42104.1 - 0.16 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 RTA1 PF04479.13 KEZ42105.1 - 5.6e-56 189.4 9.0 8.9e-56 188.8 9.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 KEZ42105.1 - 0.00035 19.5 1.2 0.00074 18.4 1.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_9_N PF15420.6 KEZ42105.1 - 0.00046 20.3 3.3 0.00046 20.3 3.3 2.2 1 1 1 2 2 2 1 Alpha/beta-hydrolase family N-terminus NDUF_B4 PF07225.12 KEZ42105.1 - 0.035 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Hydrophobin PF01185.18 KEZ42106.1 - 2.1e-08 34.7 7.6 5e-08 33.5 7.4 1.7 1 1 1 2 2 2 2 Fungal hydrophobin TMP-TENI PF02581.17 KEZ42106.1 - 0.069 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase p450 PF00067.22 KEZ42107.1 - 1.3e-51 175.8 0.0 2e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S13 PF02113.15 KEZ42108.1 - 9.1e-92 308.1 0.0 1.1e-91 307.8 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.20 KEZ42108.1 - 0.00036 20.0 0.0 0.0033 16.9 0.0 2.0 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Cadherin-like PF12733.7 KEZ42108.1 - 0.062 13.8 0.9 0.13 12.8 0.2 1.9 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain Fringe PF02434.16 KEZ42109.1 - 5e-05 22.9 0.5 0.00051 19.6 0.5 2.3 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KEZ42109.1 - 0.017 15.0 0.5 0.017 15.0 0.5 1.9 2 0 0 2 2 2 0 PAN domain Galactosyl_T PF01762.21 KEZ42109.1 - 0.058 13.2 0.0 0.18 11.6 0.0 1.8 1 1 1 2 2 2 0 Galactosyltransferase Glyco_hydro_61 PF03443.14 KEZ42111.1 - 9.3e-51 172.7 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KEZ42112.1 - 6e-23 81.3 7.8 7.6e-23 81.0 7.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 KEZ42113.1 - 1.5e-60 205.3 1.3 1.8e-60 205.0 1.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KEZ42114.1 - 2.5e-32 112.4 13.1 3e-32 112.1 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42114.1 - 3.5e-10 39.3 17.7 5.6e-10 38.7 17.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ42114.1 - 0.005 15.3 2.4 0.006 15.1 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Vps62 PF06101.11 KEZ42116.1 - 6.8e-13 47.8 0.5 5.6e-11 41.4 0.1 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 UPF0016 PF01169.19 KEZ42116.1 - 0.19 12.1 0.7 0.36 11.2 0.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 Helicase_C PF00271.31 KEZ42117.1 - 7.5e-12 45.6 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KEZ42117.1 - 1.1e-10 40.8 0.0 3.3e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_5 PF14634.6 KEZ42117.1 - 0.0001 22.2 2.6 0.0002 21.3 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KEZ42117.1 - 0.014 15.2 2.7 0.034 14.0 2.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Anti-TRAP PF15777.5 KEZ42117.1 - 0.044 13.7 8.4 0.073 13.0 3.7 3.1 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_2 PF13639.6 KEZ42117.1 - 0.068 13.5 3.3 0.14 12.5 3.3 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KEZ42117.1 - 0.072 13.0 3.9 0.19 11.6 3.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KEZ42117.1 - 0.1 12.7 3.9 0.24 11.6 1.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KEZ42117.1 - 0.4 10.6 3.1 1.3 8.9 3.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KEZ42117.1 - 1.8 8.4 4.0 4.2 7.2 4.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 KEZ42117.1 - 3.7 7.7 5.7 12 6.0 5.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon NACHT PF05729.12 KEZ42118.1 - 4.1e-08 33.3 0.1 1.1e-07 31.9 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 KEZ42118.1 - 3.2e-07 30.8 0.0 0.013 16.1 0.0 2.9 3 0 0 3 3 2 2 Ankyrin repeats (3 copies) AAA_22 PF13401.6 KEZ42118.1 - 1.6e-06 28.4 0.0 0.00041 20.6 0.1 3.0 2 0 0 2 2 2 1 AAA domain Ank_5 PF13857.6 KEZ42118.1 - 0.00012 22.3 0.0 0.0094 16.2 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ42118.1 - 0.00014 22.0 0.0 0.023 15.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KEZ42118.1 - 0.00029 21.1 0.1 0.0024 18.2 0.0 2.7 3 0 0 3 3 2 1 Ankyrin repeat Ank_4 PF13637.6 KEZ42118.1 - 0.00044 20.8 0.0 0.16 12.6 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Goodbye PF17109.5 KEZ42118.1 - 0.00045 20.7 1.2 0.0012 19.2 0.0 2.4 3 0 0 3 3 2 1 fungal STAND N-terminal Goodbye domain ATPase PF06745.13 KEZ42118.1 - 0.001 18.5 0.4 0.0028 17.0 0.1 1.8 2 0 0 2 2 2 1 KaiC AAA_16 PF13191.6 KEZ42118.1 - 0.0021 18.5 1.5 0.0055 17.1 0.1 2.5 2 0 0 2 2 1 1 AAA ATPase domain Na_sulph_symp PF00939.19 KEZ42118.1 - 0.0054 15.8 0.1 0.0084 15.2 0.1 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region NB-ARC PF00931.22 KEZ42118.1 - 0.023 13.9 0.3 0.067 12.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KEZ42118.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ42118.1 - 0.074 13.2 0.2 0.46 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KEZ42118.1 - 0.12 11.6 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 KEZ42118.1 - 0.15 11.8 0.5 0.73 9.5 0.0 2.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Cu_amine_oxid PF01179.20 KEZ42120.1 - 9.6e-34 117.0 0.0 1.2e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.20 KEZ42121.1 - 7e-30 104.3 0.2 8.9e-30 103.9 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain HNH_2 PF13391.6 KEZ42121.1 - 1.9e-07 31.1 0.0 4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Clr5 PF14420.6 KEZ42122.1 - 2.4e-10 40.5 0.7 3.4e-10 40.0 0.7 1.2 1 0 0 1 1 1 1 Clr5 domain DUF2482 PF10655.9 KEZ42122.1 - 0.091 13.3 0.3 0.13 12.8 0.3 1.2 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) Sugar_tr PF00083.24 KEZ42123.1 - 2.9e-26 92.4 26.4 2.5e-15 56.3 10.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Vfa1 PF08432.10 KEZ42123.1 - 3.5 7.9 5.4 5.9 7.2 5.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Amidase PF01425.21 KEZ42124.1 - 2.3e-40 138.9 0.0 7.1e-22 78.0 0.0 2.1 1 1 1 2 2 2 2 Amidase Isochorismatase PF00857.20 KEZ42124.1 - 3e-34 118.7 0.0 6.9e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Isochorismatase family Fructosamin_kin PF03881.14 KEZ42125.1 - 4.1e-42 144.3 0.0 5.3e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEZ42125.1 - 0.00024 21.1 0.0 0.00063 19.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3176 PF11374.8 KEZ42126.1 - 3.1e-29 101.3 1.6 3.1e-29 101.3 1.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Ank_2 PF12796.7 KEZ42127.1 - 3.1e-23 82.2 0.1 0.00023 21.7 0.0 5.4 3 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ42127.1 - 1.2e-17 62.1 0.5 0.21 12.2 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KEZ42127.1 - 1.4e-17 63.5 2.5 0.017 15.4 0.1 6.9 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ42127.1 - 1.5e-15 57.3 2.8 0.023 15.3 0.0 7.7 6 2 1 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42127.1 - 3.5e-14 52.5 6.9 0.0047 17.3 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Mid2 PF04478.12 KEZ42128.1 - 0.013 15.3 0.0 0.091 12.6 0.0 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Gram_pos_anchor PF00746.21 KEZ42128.1 - 0.064 13.2 1.0 0.19 11.7 1.0 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif HET PF06985.11 KEZ42130.1 - 1.6e-12 48.0 0.0 4.3e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1054 PF06335.12 KEZ42130.1 - 0.045 13.7 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Helicase_C PF00271.31 KEZ42131.1 - 2.7e-06 27.7 0.0 5.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ42132.1 - 2.6e-15 56.7 0.0 4.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KEZ42132.1 - 7.9e-14 52.0 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KEZ42132.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SWI2_SNF2 PF18766.1 KEZ42132.1 - 0.19 11.4 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase FAA_hydrolase PF01557.18 KEZ42133.1 - 1.9e-62 210.8 0.0 2.9e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_1 PF00561.20 KEZ42133.1 - 1.4e-26 93.7 0.0 4.5e-19 69.1 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ42133.1 - 1.2e-22 81.6 3.1 1.7e-22 81.1 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ42133.1 - 2.5e-18 66.2 0.0 5.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KEZ42133.1 - 2.8e-11 43.5 0.4 6.5e-08 32.6 1.4 2.3 1 1 1 2 2 2 2 Serine hydrolase Ndr PF03096.14 KEZ42133.1 - 0.0027 16.4 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF2437 PF10370.9 KEZ42133.1 - 0.018 16.0 0.1 0.057 14.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) Abhydrolase_4 PF08386.10 KEZ42133.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Na_H_Exchanger PF00999.21 KEZ42134.1 - 5.1e-44 150.6 16.3 6.2e-44 150.3 16.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.8 KEZ42134.1 - 2.5 8.1 4.2 15 5.6 0.1 2.9 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TauD PF02668.16 KEZ42135.1 - 1.9e-37 129.5 0.0 2.7e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KEZ42136.1 - 2.1e-89 300.4 21.7 2.5e-89 300.3 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42136.1 - 2.2e-29 102.5 22.1 2.2e-29 102.5 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ42136.1 - 0.00011 20.8 1.3 0.00011 20.8 1.3 2.0 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF543 PF04418.12 KEZ42136.1 - 0.073 13.1 0.8 0.3 11.1 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Ost4 PF10215.9 KEZ42136.1 - 0.35 10.7 1.7 5.2 7.0 0.1 2.8 2 0 0 2 2 2 0 Oligosaccaryltransferase UCR_TM PF02921.14 KEZ42136.1 - 0.81 10.2 2.2 11 6.6 0.0 3.2 3 0 0 3 3 3 0 Ubiquinol cytochrome reductase transmembrane region HET PF06985.11 KEZ42137.1 - 8.8e-19 68.3 0.0 2.7e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MAGE PF01454.19 KEZ42137.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 MAGE family FAD_binding_3 PF01494.19 KEZ42138.1 - 1.6e-15 57.2 2.6 7.4e-15 55.0 0.4 2.4 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ42138.1 - 3.1e-06 27.3 0.1 7.3e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ42138.1 - 6.7e-05 22.3 0.5 0.00039 19.8 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ42138.1 - 0.00056 19.6 4.7 0.0014 18.3 4.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ42138.1 - 0.0035 17.3 3.6 0.0067 16.4 1.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEZ42138.1 - 0.0039 16.3 1.3 0.0039 16.3 1.3 2.1 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KEZ42138.1 - 0.009 14.9 0.1 0.38 9.5 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 KEZ42138.1 - 0.009 14.8 0.2 0.017 13.8 0.2 1.5 1 1 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KEZ42138.1 - 0.021 14.1 0.1 0.043 13.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KEZ42138.1 - 0.034 13.2 0.7 0.56 9.2 0.7 2.3 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEZ42138.1 - 0.075 12.3 0.1 0.15 11.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ42138.1 - 0.13 12.8 0.1 0.36 11.4 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CorA PF01544.18 KEZ42139.1 - 3.8e-07 29.7 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Beta-lactamase PF00144.24 KEZ42140.1 - 3.9e-14 52.6 0.0 2.5e-12 46.7 0.0 2.3 2 1 0 2 2 2 2 Beta-lactamase PhzC-PhzF PF02567.16 KEZ42141.1 - 3.6e-40 138.2 0.0 1.2e-39 136.5 0.0 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein OTT_1508_deam PF14441.6 KEZ42142.1 - 1.6e-18 66.5 0.9 3.2e-18 65.5 0.9 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Fungus-induced PF10917.8 KEZ42143.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungus-induced protein PLA2_B PF01735.18 KEZ42144.1 - 1.3e-169 564.7 0.0 1.5e-169 564.5 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MFS_1 PF07690.16 KEZ42145.1 - 1.2e-36 126.4 54.4 1.6e-36 126.0 54.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-MYND PF01753.18 KEZ42146.1 - 5.2e-06 26.5 2.7 1.2e-05 25.3 2.7 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KEZ42146.1 - 0.089 13.1 1.1 0.18 12.1 1.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3787 PF12655.7 KEZ42147.1 - 0.017 15.0 0.5 0.032 14.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) DUF3864 PF12980.7 KEZ42147.1 - 0.2 12.0 1.8 0.27 11.6 0.4 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) TPR_12 PF13424.6 KEZ42149.1 - 1.6e-15 57.1 28.2 8.5e-07 29.2 0.3 4.3 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ42149.1 - 3.8e-12 45.7 20.6 0.00053 19.8 0.6 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ42149.1 - 2.3e-09 36.8 0.0 4.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEZ42149.1 - 4.9e-07 30.1 0.0 2.8e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Paf67 PF10255.9 KEZ42149.1 - 2.4e-05 23.5 0.1 0.49 9.3 0.0 3.1 1 1 1 3 3 3 2 RNA polymerase I-associated factor PAF67 TPR_7 PF13176.6 KEZ42149.1 - 0.00078 19.3 12.3 1.2 9.4 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ42149.1 - 0.00078 19.5 0.0 6.6 7.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Patatin PF01734.22 KEZ42149.1 - 0.00096 19.4 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_6 PF13174.6 KEZ42149.1 - 0.003 18.1 0.0 17 6.3 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ42149.1 - 0.0057 17.1 6.9 0.038 14.5 1.0 4.1 2 1 3 5 5 4 1 Tetratricopeptide repeat TniB PF05621.11 KEZ42149.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein TPR_2 PF07719.17 KEZ42149.1 - 0.007 16.4 4.4 46 4.5 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ThiP_synth PF10120.9 KEZ42149.1 - 0.011 15.4 0.2 0.65 9.6 0.0 3.3 2 1 1 3 3 3 0 Thiamine-phosphate synthase ANAPC3 PF12895.7 KEZ42149.1 - 0.011 15.9 2.3 1 9.6 0.5 3.5 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.12 KEZ42149.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF2469 PF10611.9 KEZ42149.1 - 0.14 12.8 8.7 14 6.3 0.2 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF2469) YfdX PF10938.8 KEZ42149.1 - 0.23 11.4 1.3 1.8 8.5 0.1 2.9 3 1 0 3 3 3 0 YfdX protein Ank_4 PF13637.6 KEZ42151.1 - 8.7e-10 38.9 0.2 0.0003 21.3 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42151.1 - 1.9e-07 31.2 0.1 0.057 13.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KEZ42151.1 - 3.6e-07 30.7 0.1 7.3e-05 23.3 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ42151.1 - 1.8e-05 24.7 0.1 0.018 15.6 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KEZ42151.1 - 0.00072 19.8 0.0 0.016 15.5 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) SesA PF17107.5 KEZ42151.1 - 0.0028 17.8 0.3 0.079 13.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases PRTase_2 PF15609.6 KEZ42151.1 - 0.076 12.5 1.3 0.13 11.7 1.3 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Ank_2 PF12796.7 KEZ42152.1 - 4.4e-43 145.8 1.2 1.4e-11 44.9 0.2 6.6 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ42152.1 - 5.1e-41 138.5 6.0 1.2e-09 38.5 0.0 10.3 6 3 6 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ42152.1 - 6.7e-33 112.3 11.9 3.4e-10 40.0 0.0 7.7 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42152.1 - 5.8e-26 89.8 8.1 2.6e-06 27.6 0.0 9.2 10 1 1 11 11 11 6 Ankyrin repeat Fungal_trans PF04082.18 KEZ42152.1 - 3.8e-22 78.6 0.3 8.4e-22 77.5 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_3 PF13606.6 KEZ42152.1 - 7.3e-22 75.1 6.0 0.00018 21.7 0.0 9.9 10 0 0 10 10 8 3 Ankyrin repeat GST_N PF02798.20 KEZ42152.1 - 2.1e-18 66.4 0.0 5.8e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ42152.1 - 5.5e-14 52.2 0.0 1.3e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEZ42152.1 - 4.2e-13 49.4 0.0 1.3e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEZ42152.1 - 1.1e-12 48.2 0.0 1.4e-11 44.6 0.0 2.7 3 0 0 3 3 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEZ42152.1 - 9.9e-09 35.3 0.0 2.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NACHT PF05729.12 KEZ42152.1 - 2e-06 27.8 0.0 5.7e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ42152.1 - 9.6e-05 22.7 0.0 0.00032 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain GST_C_2 PF13410.6 KEZ42152.1 - 0.00021 21.3 0.0 0.00074 19.5 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain adh_short_C2 PF13561.6 KEZ42153.1 - 1.1e-54 185.4 0.1 1.4e-54 185.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ42153.1 - 1.5e-43 148.5 0.4 1.9e-43 148.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ42153.1 - 1.7e-09 37.9 0.3 8e-09 35.7 0.2 2.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KEZ42153.1 - 0.00022 20.8 0.1 0.00072 19.1 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ42153.1 - 0.21 10.9 0.1 0.36 10.2 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FMO-like PF00743.19 KEZ42154.1 - 6.5e-18 64.5 0.1 1.2e-15 57.0 0.1 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ42154.1 - 1.9e-07 31.2 0.0 5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEZ42154.1 - 4.7e-06 26.0 0.0 0.002 17.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ42154.1 - 4.6e-05 22.8 0.0 0.00089 18.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ42154.1 - 8.1e-05 22.0 0.0 0.00059 19.2 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ42154.1 - 0.022 14.1 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KEZ42154.1 - 0.031 14.2 0.1 0.44 10.5 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEZ42154.1 - 0.051 14.1 0.1 3.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KEZ42154.1 - 0.073 13.1 0.0 0.68 10.0 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.16 KEZ42155.1 - 5.7e-36 124.2 14.7 5.7e-36 124.2 14.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ42155.1 - 5.1e-09 35.5 11.5 1.2e-08 34.3 11.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter NqrM PF04400.13 KEZ42155.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM DHDPS PF00701.22 KEZ42156.1 - 2.4e-42 144.7 0.0 3e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KEZ42156.1 - 0.012 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase CbiD PF01888.17 KEZ42156.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 CbiD MFS_1 PF07690.16 KEZ42157.1 - 2.2e-36 125.5 18.9 3.6e-36 124.8 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sulf_coat_C PF12193.8 KEZ42157.1 - 0.036 14.1 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal PhyH PF05721.13 KEZ42158.1 - 3.3e-12 47.1 0.0 7.7e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KEZ42158.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase adh_short PF00106.25 KEZ42159.1 - 1.7e-37 128.8 0.4 2.7e-37 128.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ42159.1 - 3.6e-35 121.6 0.7 1e-34 120.2 0.7 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ42159.1 - 1.8e-07 31.3 1.4 3.3e-07 30.4 1.0 1.6 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 KEZ42159.1 - 0.017 15.0 1.3 0.024 14.5 1.3 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank_2 PF12796.7 KEZ42160.1 - 2.3e-23 82.5 0.0 5e-15 55.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ42160.1 - 4e-12 46.1 0.1 7.9e-10 38.8 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42160.1 - 7.2e-12 45.2 1.5 6e-06 26.5 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KEZ42160.1 - 1.4e-11 44.7 0.5 5.3e-06 26.9 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ42160.1 - 2.4e-10 39.7 0.0 0.00088 19.6 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Helo_like_N PF17111.5 KEZ42160.1 - 0.0019 17.6 0.9 0.0066 15.8 0.2 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TyeA PF09059.10 KEZ42160.1 - 0.13 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 TyeA SesA PF17107.5 KEZ42160.1 - 0.14 12.4 0.5 0.46 10.7 0.2 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases MFS_1 PF07690.16 KEZ42161.1 - 3.2e-23 82.2 47.8 7.9e-23 80.9 47.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.18 KEZ42162.1 - 0.0022 17.4 0.6 0.0039 16.5 0.3 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Rotamase_2 PF13145.6 KEZ42162.1 - 0.01 16.7 0.1 0.017 15.9 0.1 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain SopA PF13981.6 KEZ42162.1 - 0.022 15.2 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 SopA-like central domain TRIQK PF15168.6 KEZ42162.1 - 0.16 11.9 0.2 0.34 10.8 0.2 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family FAD_binding_4 PF01565.23 KEZ42163.1 - 1.1e-16 60.8 1.5 6.7e-16 58.3 1.5 2.3 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ42163.1 - 6.4e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF2545 PF10810.8 KEZ42163.1 - 0.059 13.5 0.3 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) DUF1942 PF09167.11 KEZ42163.1 - 0.13 12.2 0.5 0.42 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) DUF1748 PF08520.10 KEZ42164.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Fungal_trans PF04082.18 KEZ42166.1 - 2.7e-10 39.8 0.4 4.6e-10 39.0 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Swi3 PF07962.12 KEZ42166.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Amidase PF01425.21 KEZ42167.1 - 4.9e-56 190.6 1.9 8.5e-56 189.8 1.9 1.3 1 1 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 KEZ42167.1 - 2.9e-15 56.5 0.0 6.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ42167.1 - 8.5e-06 25.4 0.0 2.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase p450 PF00067.22 KEZ42168.1 - 2.6e-56 191.3 0.0 3.1e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 KEZ42169.1 - 3.6e-61 206.6 0.0 5.5e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KEZ42169.1 - 1.7e-23 83.4 0.0 3.5e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KEZ42169.1 - 9.3e-21 74.5 0.0 3.4e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain AA_permease PF00324.21 KEZ42170.1 - 1e-78 265.1 32.5 1.2e-78 264.8 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ42170.1 - 2.6e-18 66.1 34.5 3.2e-18 65.8 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease RRM_1 PF00076.22 KEZ42173.1 - 9.2e-09 35.0 0.1 2e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEZ42173.1 - 8e-05 22.6 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KEZ42173.1 - 0.0083 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif FAM220 PF15487.6 KEZ42174.1 - 0.97 9.0 4.7 1.6 8.3 4.7 1.3 1 0 0 1 1 1 0 FAM220 family AA_permease_2 PF13520.6 KEZ42175.1 - 7e-60 203.0 17.0 1.4e-59 202.1 16.6 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ42175.1 - 1.9e-13 49.9 7.6 6.1e-13 48.2 7.6 1.9 1 0 0 1 1 1 1 Amino acid permease DUF4149 PF13664.6 KEZ42175.1 - 0.34 11.2 7.0 3.6 8.0 0.1 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) SNARE_assoc PF09335.11 KEZ42175.1 - 3.2 8.3 23.4 0.14 12.7 1.1 4.2 4 1 0 5 5 5 0 SNARE associated Golgi protein DUF2207 PF09972.9 KEZ42175.1 - 5.4 5.7 8.2 9.5 4.9 0.0 3.6 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) NACHT PF05729.12 KEZ42176.1 - 3.8e-10 39.9 0.3 1.2e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ42176.1 - 4.5e-06 27.2 1.4 4.3e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ42176.1 - 0.0083 16.4 0.1 0.072 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEZ42176.1 - 0.025 15.0 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KEZ42176.1 - 0.033 14.7 0.9 0.58 10.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KEZ42176.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 KEZ42176.1 - 0.056 12.7 0.0 9.2 5.4 0.0 2.5 1 1 1 2 2 2 0 KAP family P-loop domain DUF4211 PF13926.6 KEZ42176.1 - 0.064 13.3 0.4 1 9.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4211) AAA_23 PF13476.6 KEZ42176.1 - 0.088 13.3 6.6 0.34 11.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KEZ42176.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF4404 PF14357.6 KEZ42176.1 - 1.4 9.6 12.3 0.35 11.5 3.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) Apolipoprotein PF01442.18 KEZ42176.1 - 2.6 7.9 12.7 2.5 7.9 11.1 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Zip PF02535.22 KEZ42177.1 - 1.4e-48 165.8 1.5 2.7e-48 164.9 1.5 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2046 PF09755.9 KEZ42178.1 - 0.015 14.5 0.0 0.015 14.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) GreA_GreB_N PF03449.15 KEZ42178.1 - 1.3 9.2 6.2 0.31 11.2 1.7 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Cyto_heme_lyase PF01265.17 KEZ42179.1 - 1.6e-122 408.7 1.9 2e-122 408.4 1.9 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase SLATT_5 PF18160.1 KEZ42180.1 - 0.17 11.2 0.2 0.17 11.2 0.2 2.3 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4173 PF13777.6 KEZ42180.1 - 0.9 8.9 14.8 0.47 9.8 7.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) AcetylCoA_hydro PF02550.15 KEZ42181.1 - 7.3e-46 156.7 0.0 1.1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KEZ42181.1 - 8.1e-41 139.5 0.0 1.3e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 KEZ42181.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Coenzyme A transferase DUF3433 PF11915.8 KEZ42182.1 - 2.4e-20 72.8 16.8 9.7e-12 45.2 1.6 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) SET PF00856.28 KEZ42184.1 - 4.7e-13 49.9 0.3 1.7e-12 48.1 0.3 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KEZ42184.1 - 4.2e-07 29.9 16.8 1.3e-06 28.4 16.8 1.9 1 0 0 1 1 1 1 MYND finger 4HBT PF03061.22 KEZ42187.1 - 1.7e-15 57.1 0.8 2.6e-15 56.5 0.8 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KEZ42187.1 - 2e-05 24.7 0.0 2.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KEZ42187.1 - 0.0094 16.2 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Tfb2 PF03849.14 KEZ42188.1 - 3.1e-132 440.9 0.0 3.7e-132 440.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KEZ42188.1 - 1e-21 77.1 0.8 2.1e-21 76.1 0.8 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KEZ42188.1 - 2.3e-06 27.8 0.1 6.5e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.14 KEZ42189.1 - 4.8 5.4 14.7 7.9 4.6 14.7 1.3 1 0 0 1 1 1 0 CDC45-like protein TB2_DP1_HVA22 PF03134.19 KEZ42190.1 - 7.7e-27 93.0 8.7 1.3e-26 92.4 8.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 KEZ42191.1 - 1.9e-80 268.3 0.0 2.5e-80 268.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 CHCH PF06747.13 KEZ42192.1 - 0.00043 20.3 4.4 0.00085 19.4 4.0 1.7 1 1 0 1 1 1 1 CHCH domain CX9C PF16860.5 KEZ42192.1 - 0.0019 18.2 1.6 0.026 14.5 0.2 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GT-D PF08759.11 KEZ42192.1 - 0.034 13.8 0.2 0.036 13.7 0.2 1.1 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold BPL_N PF09825.9 KEZ42193.1 - 7.3e-148 492.7 0.0 8.6e-148 492.4 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KEZ42193.1 - 4e-23 81.8 0.0 6.1e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KEZ42193.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Syndecan PF01034.20 KEZ42195.1 - 0.012 15.5 0.7 0.029 14.3 0.7 1.6 1 0 0 1 1 1 0 Syndecan domain Pam16 PF03656.13 KEZ42196.1 - 7.3e-33 113.3 0.1 9.5e-33 112.9 0.1 1.1 1 0 0 1 1 1 1 Pam16 Yip1 PF04893.17 KEZ42197.1 - 6.7e-07 29.2 13.4 0.00028 20.7 7.5 2.4 2 1 0 2 2 2 2 Yip1 domain LPMO_10 PF03067.15 KEZ42199.1 - 5.1e-07 30.5 0.1 9.2e-07 29.7 0.1 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading OTT_1508_deam PF14441.6 KEZ42200.1 - 4.1e-18 65.1 0.2 8.3e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase PSP PF04046.16 KEZ42200.1 - 0.05 13.5 1.1 0.22 11.4 0.1 2.3 2 0 0 2 2 2 0 PSP Glyco_hydro_67M PF07488.12 KEZ42201.1 - 1.1e-144 481.5 0.0 1.9e-144 480.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KEZ42201.1 - 6e-87 290.8 2.2 8.5e-87 290.4 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KEZ42201.1 - 8.5e-29 100.3 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus PAP_assoc PF03828.19 KEZ42202.1 - 1.1e-13 51.1 0.1 2.6e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KEZ42202.1 - 3.3e-08 33.7 0.2 1.9e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain Glyco_hydro_61 PF03443.14 KEZ42203.1 - 1.9e-49 168.4 0.1 4e-49 167.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KEZ42203.1 - 3.3e-09 36.6 16.0 3.3e-09 36.6 16.0 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 KEZ42204.1 - 3.7e-08 33.6 0.0 4.9e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KEZ42204.1 - 1.1e-06 29.2 3.6 3.9e-06 27.4 3.6 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4235 PF14019.6 KEZ42204.1 - 0.13 12.4 0.9 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Pex14_N PF04695.13 KEZ42205.1 - 0.012 16.3 2.5 0.012 16.3 2.5 3.5 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.9 KEZ42205.1 - 1.7 7.4 6.7 3.4 6.4 6.7 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KEZ42205.1 - 3.8 6.0 6.3 7.2 5.0 6.3 1.4 1 0 0 1 1 1 0 Macoilin family APH PF01636.23 KEZ42206.1 - 7.4e-08 32.6 1.6 5.5e-07 29.8 1.6 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ42206.1 - 0.0011 18.6 0.1 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase ERM PF00769.19 KEZ42208.1 - 0.072 12.9 24.7 0.13 12.0 24.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Pkinase PF00069.25 KEZ42209.1 - 3.2e-16 59.5 0.0 5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42209.1 - 9.7e-09 34.9 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ42209.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ42209.1 - 0.095 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1295 PF06966.12 KEZ42210.1 - 1.3e-12 47.8 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Fungal_trans PF04082.18 KEZ42210.1 - 5.3e-06 25.7 0.0 1.2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Steroid_dh PF02544.16 KEZ42210.1 - 0.03 14.3 0.2 0.089 12.8 0.1 1.8 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Gon7 PF08738.10 KEZ42210.1 - 0.2 11.8 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 Gon7 family NmrA PF05368.13 KEZ42211.1 - 2.5e-59 200.6 0.9 3.4e-59 200.2 0.9 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ42211.1 - 3.6e-18 66.1 0.2 5.6e-18 65.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ42211.1 - 5.2e-05 22.4 0.0 7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KEZ42211.1 - 0.038 14.3 0.2 0.24 11.7 0.1 2.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KEZ42211.1 - 0.085 12.3 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acetyltransf_7 PF13508.7 KEZ42212.1 - 6.6e-05 23.3 0.1 0.00055 20.3 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ42212.1 - 0.0094 16.6 0.1 0.33 11.6 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Lipocalin_5 PF13924.6 KEZ42214.1 - 2.1e-13 50.3 0.0 2.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain NUP PF06516.11 KEZ42215.1 - 4.2e-125 417.1 0.0 4.8e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.25 KEZ42216.1 - 1.7e-41 142.3 0.0 4.4e-41 141.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42216.1 - 4.5e-30 104.8 0.0 6.9e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEZ42216.1 - 0.042 13.2 0.0 0.19 11.0 0.0 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ42216.1 - 0.079 11.7 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KEZ42216.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pyr_redox_2 PF07992.14 KEZ42217.1 - 8.4e-50 169.6 0.7 1.1e-49 169.3 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ42217.1 - 1.6e-18 67.0 0.1 1.8e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ42217.1 - 1.7e-16 60.5 0.0 6e-15 55.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ42217.1 - 7.7e-05 21.9 1.8 1 8.3 0.1 4.0 3 1 1 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KEZ42217.1 - 0.00011 22.6 0.0 0.0024 18.3 0.0 2.4 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KEZ42217.1 - 0.00015 21.9 0.1 0.096 12.9 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEZ42217.1 - 0.0011 18.2 0.1 0.0069 15.6 0.1 2.2 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KEZ42217.1 - 0.0072 15.7 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KEZ42217.1 - 0.0089 15.7 1.0 2.2 7.8 0.0 3.1 2 2 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ42217.1 - 0.016 14.4 0.4 13 4.9 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.24 KEZ42217.1 - 0.043 12.9 4.8 1.1 8.2 0.1 3.4 3 1 0 4 4 4 0 FAD binding domain Thi4 PF01946.17 KEZ42217.1 - 0.12 11.6 0.1 0.54 9.4 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Vps53_N PF04100.12 KEZ42218.1 - 7e-103 344.5 0.4 1.4e-102 343.5 0.4 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal RINT1_TIP1 PF04437.13 KEZ42218.1 - 1.9e-05 23.8 0.4 0.0025 16.8 0.0 2.8 3 0 0 3 3 3 1 RINT-1 / TIP-1 family Sec6 PF06046.13 KEZ42218.1 - 2.2e-05 23.0 1.9 0.0002 19.9 0.2 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec6 Vps54_N PF10475.9 KEZ42218.1 - 5.2e-05 22.7 4.2 9.6e-05 21.8 4.2 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KEZ42218.1 - 0.00013 21.8 0.1 0.0003 20.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec15 PF04091.12 KEZ42218.1 - 0.00083 18.9 0.3 0.0017 17.9 0.1 1.6 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Zw10 PF06248.13 KEZ42218.1 - 0.018 13.7 3.2 0.03 12.9 3.2 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Spc7 PF08317.11 KEZ42218.1 - 0.02 13.8 2.3 0.036 13.0 2.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FliG_N PF14842.6 KEZ42218.1 - 0.059 13.9 0.1 0.24 12.0 0.1 2.0 1 0 0 1 1 1 0 FliG N-terminal domain XhlA PF10779.9 KEZ42218.1 - 0.074 13.3 1.6 0.33 11.2 0.7 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 KEZ42218.1 - 0.16 12.0 1.5 0.65 10.0 1.5 2.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 KEZ42218.1 - 0.35 11.4 2.6 0.49 10.9 1.4 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region FlaC_arch PF05377.11 KEZ42218.1 - 0.67 10.4 4.9 74 3.9 0.1 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4404 PF14357.6 KEZ42218.1 - 6.9 7.4 5.8 65 4.3 0.9 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Amidase PF01425.21 KEZ42219.1 - 1.6e-91 307.6 0.0 2e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1776 PF08643.10 KEZ42220.1 - 1.2e-96 323.6 0.0 1.6e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Methyltransf_25 PF13649.6 KEZ42220.1 - 2.8e-12 47.2 0.0 8e-12 45.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42220.1 - 1.5e-11 44.8 0.0 3.5e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42220.1 - 2e-11 43.9 0.0 3.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42220.1 - 4.4e-07 30.6 0.0 8.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ42220.1 - 5.9e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ42220.1 - 3.1e-06 27.1 0.0 6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KEZ42220.1 - 9.7e-05 22.0 0.0 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain adh_short PF00106.25 KEZ42220.1 - 0.00064 19.2 0.0 0.0028 17.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase CMAS PF02353.20 KEZ42220.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KEZ42220.1 - 0.024 14.0 0.1 0.037 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KEZ42220.1 - 0.043 13.8 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KEZ42220.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 KEZ42220.1 - 0.13 11.6 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family zf_CCCH_4 PF18345.1 KEZ42221.1 - 1.5e-10 40.7 10.4 1.1e-06 28.4 2.2 2.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KEZ42221.1 - 2.2e-09 37.0 5.9 1.9e-05 24.5 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEZ42221.1 - 1.5e-08 34.2 6.5 2.7e-05 23.8 0.4 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KEZ42221.1 - 1.9e-07 31.8 5.4 0.00014 22.5 0.4 2.2 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KEZ42221.1 - 1.1 9.5 3.7 9 6.6 3.6 2.0 1 1 0 1 1 1 0 Zinc-finger containing family Scm3 PF10384.9 KEZ42222.1 - 2.5e-23 81.6 0.4 5.9e-23 80.4 0.0 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 Pkinase PF00069.25 KEZ42223.1 - 4.9e-64 216.2 0.1 5.6e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42223.1 - 7.8e-19 68.0 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ42223.1 - 1.7e-08 34.7 0.0 4.6e-06 26.7 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ42223.1 - 0.0072 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEZ42223.1 - 0.023 14.1 0.3 0.038 13.3 0.3 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEZ42223.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KEZ42223.1 - 0.038 13.6 2.0 0.038 13.6 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase Atg14 PF10186.9 KEZ42224.1 - 1.4e-61 208.4 0.0 1.8e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HalX PF08663.10 KEZ42224.1 - 0.88 9.9 6.3 3.6 8.0 3.9 2.3 1 1 1 2 2 2 0 HalX domain Spc7_N PF15402.6 KEZ42226.1 - 6.2e-178 594.0 86.4 5.7e-177 590.8 79.7 3.3 2 1 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KEZ42226.1 - 1.5e-119 398.5 7.1 1.5e-119 398.5 7.1 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KEZ42226.1 - 7.7e-17 61.1 0.3 1.5e-16 60.2 0.3 1.5 1 0 0 1 1 1 1 Spc7_C2 APG6_N PF17675.1 KEZ42226.1 - 0.0028 18.2 6.8 0.0028 18.2 6.8 3.1 3 0 0 3 3 3 1 Apg6 coiled-coil region HMMR_N PF15905.5 KEZ42226.1 - 0.0068 15.9 7.2 0.025 14.0 7.2 2.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal COG2 PF06148.11 KEZ42226.1 - 0.15 12.2 1.3 0.46 10.6 1.3 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S17_N PF16205.5 KEZ42227.1 - 6.8e-32 109.7 0.2 1.3e-31 108.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KEZ42227.1 - 4.4e-27 94.0 3.6 4.8e-27 93.9 2.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 ER_lumen_recept PF00810.18 KEZ42230.1 - 2e-42 145.5 12.5 3.1e-42 144.9 12.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KEZ42230.1 - 0.0038 16.9 1.4 0.094 12.5 0.0 3.1 2 1 0 2 2 2 1 PQ loop repeat DUF1516 PF07457.11 KEZ42230.1 - 0.025 14.8 0.5 0.061 13.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF4181 PF13789.6 KEZ42230.1 - 7.4 6.9 11.3 0.17 12.1 3.6 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) RRM_1 PF00076.22 KEZ42231.1 - 6.2e-13 48.4 0.1 9.4e-13 47.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ42231.1 - 0.063 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PhoD PF09423.10 KEZ42232.1 - 0.14 11.1 0.0 0.28 10.1 0.0 1.5 1 1 0 1 1 1 0 PhoD-like phosphatase Peptidase_S8 PF00082.22 KEZ42233.1 - 3.1e-37 128.5 0.7 5.4e-37 127.7 0.7 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KEZ42233.1 - 4.6e-25 87.5 2.3 8.7e-25 86.6 2.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.24 KEZ42234.1 - 8.3e-21 74.1 0.4 6.1e-20 71.3 0.2 2.3 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 KEZ42234.1 - 2.1e-09 37.3 12.6 6e-06 26.0 1.8 2.2 2 0 0 2 2 2 2 Vps5 C terminal like AlkA_N PF06029.11 KEZ42234.1 - 0.014 15.6 0.1 0.053 13.8 0.0 2.0 2 0 0 2 2 2 0 AlkA N-terminal domain BAR_3 PF16746.5 KEZ42234.1 - 0.032 13.9 8.1 0.21 11.3 0.2 2.7 2 1 1 3 3 3 0 BAR domain of APPL family DIT1_PvcA PF05141.12 KEZ42234.1 - 0.088 12.3 2.2 0.073 12.5 0.8 1.5 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein DUF2913 PF11140.8 KEZ42234.1 - 0.26 11.0 2.3 0.42 10.3 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) FlaC_arch PF05377.11 KEZ42234.1 - 0.36 11.2 3.2 33 5.0 1.2 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Sec34 PF04136.15 KEZ42234.1 - 1.1 9.2 5.6 0.22 11.4 0.2 2.4 2 1 1 3 3 3 0 Sec34-like family Occludin_ELL PF07303.13 KEZ42234.1 - 1.8 9.3 7.7 2.3 9.0 0.0 3.5 2 1 1 3 3 3 0 Occludin homology domain DUF1664 PF07889.12 KEZ42234.1 - 2.4 8.2 7.1 4 7.5 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TerB PF05099.13 KEZ42234.1 - 2.7 7.9 10.7 11 6.0 1.8 3.2 3 0 0 3 3 3 0 Tellurite resistance protein TerB CCT_2 PF09425.10 KEZ42234.1 - 3.4 7.6 5.5 6.5 6.7 1.4 2.5 2 0 0 2 2 2 0 Divergent CCT motif DUF4298 PF14131.6 KEZ42234.1 - 3.5 7.7 7.4 2.2 8.3 0.6 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4298) MRPL52 PF18699.1 KEZ42234.1 - 4.2 7.6 6.0 2 8.6 2.6 2.1 2 0 0 2 2 2 0 Mitoribosomal protein mL52 ADK PF00406.22 KEZ42235.1 - 4.4e-38 130.7 0.0 1.2e-19 70.9 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 KEZ42235.1 - 3.9e-16 59.7 0.0 3.5e-10 40.5 0.1 2.3 1 1 0 2 2 2 2 AAA domain ADK_lid PF05191.14 KEZ42235.1 - 2.1e-14 53.2 0.0 3.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KEZ42235.1 - 5.5e-05 23.7 0.0 0.0012 19.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEZ42235.1 - 0.00075 19.7 0.0 0.002 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEZ42235.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LETM1 PF07766.13 KEZ42236.1 - 1.7e-102 342.3 1.3 3.8e-102 341.2 1.3 1.6 1 0 0 1 1 1 1 LETM1-like protein CTD PF12815.7 KEZ42236.1 - 2.8e-24 85.4 35.9 4.7e-18 65.5 19.6 4.3 2 2 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 KEZ42236.1 - 3.1e-22 78.3 0.0 6.2e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KEZ42236.1 - 1.1e-19 71.2 8.3 1.1e-19 71.2 8.3 4.9 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KEZ42236.1 - 5.1e-05 23.1 24.2 0.0034 17.3 4.3 4.9 5 0 0 5 5 5 2 KOW motif DUF3912 PF13051.6 KEZ42236.1 - 0.0037 17.5 0.3 0.081 13.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) SAP PF02037.27 KEZ42236.1 - 0.011 15.5 0.0 0.091 12.5 0.0 2.4 2 0 0 2 2 2 0 SAP domain ATP-synt_ab_N PF02874.23 KEZ42236.1 - 0.052 14.1 1.6 0.41 11.2 0.3 2.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain WD40 PF00400.32 KEZ42237.1 - 5.2e-14 52.4 6.5 2e-06 28.4 0.1 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1748 PF08520.10 KEZ42238.1 - 6.1e-31 106.1 0.0 7.3e-31 105.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 KEZ42239.1 - 2e-161 536.7 2.1 2.9e-161 536.2 2.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KEZ42239.1 - 1.1e-29 103.0 0.0 2.3e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KEZ42239.1 - 0.0011 18.1 0.9 0.0034 16.5 0.3 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KEZ42239.1 - 0.0028 16.7 0.0 0.021 13.9 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glyco_hydro_61 PF03443.14 KEZ42240.1 - 1.4e-60 204.7 0.1 1.7e-60 204.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1768 PF08719.11 KEZ42241.1 - 6.8e-56 188.9 0.0 8.1e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.25 KEZ42242.1 - 6.2e-46 156.9 0.0 9.6e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KEZ42242.1 - 3.8e-37 125.6 20.4 9.5e-09 35.8 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 KEZ42242.1 - 3e-24 85.7 0.0 4.6e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 KEZ42242.1 - 1.1e-17 64.1 5.7 0.11 12.8 0.0 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEZ42242.1 - 1.3e-06 28.2 9.4 0.00036 20.2 3.0 2.3 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.8 KEZ42242.1 - 8.7e-06 24.7 7.3 0.45 9.1 0.0 5.0 3 3 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ42242.1 - 0.00068 18.7 4.9 1.5 7.7 0.1 4.7 2 2 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEZ42242.1 - 0.0088 15.4 0.2 0.31 10.3 0.0 2.6 2 1 0 2 2 2 1 WD40-like domain Kinase-like PF14531.6 KEZ42242.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KEZ42242.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PALB2_WD40 PF16756.5 KEZ42242.1 - 0.042 12.8 3.1 6.1 5.7 0.0 4.2 2 1 4 6 6 6 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KEZ42242.1 - 0.067 11.5 0.0 0.13 10.6 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz UQ_con PF00179.26 KEZ42243.1 - 5.3e-47 159.0 0.0 6.1e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ42243.1 - 1.4e-05 24.8 0.0 1.8e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KEZ42243.1 - 0.0073 16.6 0.0 0.0079 16.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KEZ42243.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.4 1 1 0 1 1 1 0 UEV domain Ribosomal_L31e PF01198.19 KEZ42244.1 - 4.1e-40 135.9 0.3 5.2e-40 135.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.19 KEZ42245.1 - 1.7e-11 44.4 0.0 3.1e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Cytochrom_B_C PF00032.17 KEZ42245.1 - 0.11 12.8 1.4 0.22 11.8 0.3 2.0 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD PCI PF01399.27 KEZ42246.1 - 3.9e-08 33.8 0.0 7.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain YhzD PF14120.6 KEZ42246.1 - 0.058 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 YhzD-like protein MIF4G_like PF09088.11 KEZ42246.1 - 0.083 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 MIF4G like E1-E2_ATPase PF00122.20 KEZ42247.1 - 5.8e-50 169.3 0.7 1.7e-49 167.8 0.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KEZ42247.1 - 9e-47 157.4 2.8 6.3e-12 45.8 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KEZ42247.1 - 7.3e-42 144.0 1.0 1.8e-41 142.8 1.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ42247.1 - 4.2e-05 23.4 1.1 0.00013 21.8 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF155 PF02582.14 KEZ42248.1 - 8.2e-54 182.4 0.1 1.6e-53 181.4 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.17 KEZ42248.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain Sugar_tr PF00083.24 KEZ42249.1 - 2.3e-41 142.1 17.1 4e-41 141.3 17.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42249.1 - 6.9e-36 123.9 25.5 1.4e-27 96.6 10.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ42249.1 - 0.032 12.6 3.3 0.024 13.1 0.6 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) zinc_ribbon_15 PF17032.5 KEZ42250.1 - 0.00069 20.3 0.6 0.00091 19.9 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbon family SDA1 PF05285.12 KEZ42251.1 - 0.0016 18.0 15.2 0.0021 17.6 15.2 1.1 1 0 0 1 1 1 1 SDA1 Utp14 PF04615.13 KEZ42251.1 - 0.2 10.2 10.0 0.25 9.9 10.0 1.1 1 0 0 1 1 1 0 Utp14 protein TFIIF_alpha PF05793.12 KEZ42251.1 - 0.3 9.6 14.7 0.39 9.3 14.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KEZ42251.1 - 0.6 8.2 19.2 0.78 7.9 19.2 1.0 1 0 0 1 1 1 0 Nop14-like family PNISR PF15996.5 KEZ42251.1 - 0.83 9.9 8.3 1.5 9.1 8.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR BUD22 PF09073.10 KEZ42251.1 - 1.3 8.2 13.9 1.9 7.7 13.9 1.1 1 0 0 1 1 1 0 BUD22 PTPRCAP PF15713.5 KEZ42251.1 - 1.8 8.8 13.4 1.8 8.9 5.5 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 KEZ42251.1 - 3.3 6.4 6.4 4.9 5.8 6.4 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 KEZ42251.1 - 5.2 8.1 9.4 5.5e+02 1.6 9.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) GREB1 PF15782.5 KEZ42251.1 - 9.7 3.2 6.1 12 2.8 6.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1295 PF06966.12 KEZ42253.1 - 6.8e-58 196.0 0.1 8.8e-58 195.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KEZ42253.1 - 0.00053 20.4 1.2 0.0011 19.3 0.0 2.2 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 KEZ42253.1 - 0.00056 19.9 0.0 0.0021 18.1 0.0 1.9 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KEZ42253.1 - 0.015 15.7 2.1 0.047 14.1 0.1 2.7 3 0 0 3 3 3 0 Phospholipid methyltransferase DUF5305 PF17231.2 KEZ42253.1 - 0.19 11.1 0.0 9.5 5.6 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF1229 PF06797.11 KEZ42253.1 - 5.2 7.3 8.0 0.44 10.8 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1229) Med8 PF10232.9 KEZ42255.1 - 4e-32 111.7 1.1 5.1e-32 111.3 1.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 ERK-JNK_inhib PF15002.6 KEZ42255.1 - 0.12 12.1 1.1 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor DUF2052 PF09747.9 KEZ42255.1 - 0.42 10.7 10.2 0.77 9.8 10.2 1.7 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 KEZ42255.1 - 1.9 8.2 7.2 19 5.0 0.1 2.7 2 1 1 3 3 3 0 Pox virus Ag35 surface protein NOA36 PF06524.12 KEZ42255.1 - 2.7 7.2 5.0 3.9 6.7 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KEZ42255.1 - 3 5.8 4.3 4.2 5.4 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 KEZ42255.1 - 4.8 6.1 8.8 6.5 5.6 8.8 1.1 1 0 0 1 1 1 0 Paf1 Sulfatase PF00884.23 KEZ42256.1 - 9.2e-56 189.5 0.0 1.1e-55 189.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KEZ42256.1 - 7.2e-27 93.0 1.1 1.2e-26 92.2 0.4 1.8 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KEZ42256.1 - 3.9e-09 36.6 0.0 0.0028 17.3 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase RasGAP PF00616.19 KEZ42257.1 - 4.3e-50 170.3 0.0 9.3e-50 169.2 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KEZ42257.1 - 2.4e-47 160.5 5.3 2.4e-47 160.5 5.3 2.1 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 KEZ42257.1 - 6.4e-15 53.5 45.0 0.025 14.3 0.5 12.7 13 0 0 13 13 13 8 IQ calmodulin-binding motif CH PF00307.31 KEZ42257.1 - 1.2e-11 44.7 0.1 8.3e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain IZUMO PF15005.6 KEZ42257.1 - 0.46 11.0 4.3 0.21 12.1 0.6 2.5 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated ABC_tran PF00005.27 KEZ42258.1 - 4.4e-38 130.9 0.0 3.1e-29 102.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEZ42258.1 - 1.7e-32 113.1 29.2 3.4e-24 86.0 10.9 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KEZ42258.1 - 2.8e-10 40.0 0.0 6.8e-05 22.4 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain CDC45 PF02724.14 KEZ42258.1 - 0.0059 15.0 0.1 0.0059 15.0 0.1 1.5 2 0 0 2 2 2 1 CDC45-like protein Zip PF02535.22 KEZ42258.1 - 0.0062 15.8 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 ZIP Zinc transporter FAM176 PF14851.6 KEZ42258.1 - 0.013 15.1 3.8 0.046 13.4 0.9 3.0 3 0 0 3 3 3 0 FAM176 family MMR_HSR1 PF01926.23 KEZ42258.1 - 0.06 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 KEZ42258.1 - 0.089 13.0 0.1 10 6.4 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KEZ42258.1 - 0.092 13.1 0.2 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Presenilin PF01080.17 KEZ42258.1 - 0.15 10.8 2.6 0.33 9.7 2.6 1.6 1 0 0 1 1 1 0 Presenilin AAA_21 PF13304.6 KEZ42258.1 - 1.4 8.7 7.0 5.8 6.6 0.5 3.7 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Sec62 PF03839.16 KEZ42258.1 - 1.6 8.2 4.5 4.6 6.7 3.7 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 WD40 PF00400.32 KEZ42259.1 - 5.6e-14 52.3 13.6 0.0031 18.3 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42259.1 - 3.3e-11 43.3 0.0 0.0042 17.3 0.0 4.7 3 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KEZ42259.1 - 0.0043 16.9 3.4 5.4 7.1 0.4 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KEZ42259.1 - 0.036 13.9 0.1 0.41 10.5 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A NAD_binding_1 PF00175.21 KEZ42260.1 - 1.3e-31 109.4 0.0 2.3e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEZ42260.1 - 1.7e-24 86.0 0.0 5.4e-24 84.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEZ42260.1 - 1.2e-08 35.2 0.0 0.0005 20.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KEZ42260.1 - 0.0015 18.7 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Ssu72 PF04722.13 KEZ42261.1 - 2.5e-84 281.6 0.0 2.8e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.11 KEZ42262.1 - 7.8e-22 76.6 4.6 1.1e-11 44.2 0.9 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT PSII_Pbs27 PF13326.6 KEZ42262.1 - 0.033 14.5 14.9 0.017 15.4 7.0 3.0 3 0 0 3 3 3 0 Photosystem II Pbs27 Fez1 PF06818.15 KEZ42262.1 - 0.082 13.4 31.0 0.26 11.7 9.0 2.4 2 0 0 2 2 2 0 Fez1 DUF1843 PF08898.10 KEZ42262.1 - 0.75 10.3 5.2 0.24 11.9 0.6 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF1843) EzrA PF06160.12 KEZ42262.1 - 1.1 7.4 21.7 0.099 10.8 4.9 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2935 PF11155.8 KEZ42262.1 - 1.1 9.6 3.9 37 4.7 1.1 3.5 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF5344 PF17279.2 KEZ42262.1 - 3 8.5 10.1 12 6.5 3.3 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5344) OmpH PF03938.14 KEZ42262.1 - 4.2 7.7 38.2 3 8.2 2.0 3.7 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) CALCOCO1 PF07888.11 KEZ42262.1 - 4.2 6.1 42.7 1.5 7.6 17.9 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cor1 PF04803.12 KEZ42262.1 - 4.3 7.6 23.2 3 8.1 8.8 2.9 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region PRKG1_interact PF15898.5 KEZ42262.1 - 4.5 8.2 37.8 2.9 8.8 12.1 3.8 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain FAM76 PF16046.5 KEZ42262.1 - 7.8 5.8 16.2 0.44 9.9 5.4 2.4 2 0 0 2 2 2 0 FAM76 protein TFR_dimer PF04253.15 KEZ42263.1 - 1.9e-28 99.0 0.0 3.4e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KEZ42263.1 - 1.6e-20 73.7 0.0 2.9e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEZ42263.1 - 1e-07 31.9 0.2 6.3e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KEZ42263.1 - 0.19 11.1 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Fructosamin_kin PF03881.14 KEZ42264.1 - 9.3e-35 120.2 0.0 1.2e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEZ42264.1 - 3.3e-06 27.2 0.0 6.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4800 PF16057.5 KEZ42264.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) ANAPC4_WD40 PF12894.7 KEZ42265.1 - 1.9e-07 31.3 0.0 0.36 11.2 0.0 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEZ42265.1 - 0.00066 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 KEZ42265.1 - 0.039 14.8 3.8 34 5.5 0.1 5.3 3 1 1 4 4 4 0 WD domain, G-beta repeat AAA_16 PF13191.6 KEZ42265.1 - 0.063 13.7 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEZ42265.1 - 0.088 13.1 0.0 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain WD40_like PF17005.5 KEZ42265.1 - 0.15 11.3 0.0 0.64 9.3 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain AAA_19 PF13245.6 KEZ42265.1 - 0.16 12.3 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 KEZ42267.1 - 0.012 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ42268.1 - 2.6e-22 79.2 36.2 9e-19 67.6 21.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 KEZ42268.1 - 0.0094 14.6 2.5 0.021 13.4 0.2 2.0 2 0 0 2 2 2 1 Ferroportin1 (FPN1) Sugar_tr PF00083.24 KEZ42268.1 - 0.027 13.3 16.4 0.036 12.9 0.7 4.1 2 1 2 4 4 4 0 Sugar (and other) transporter DUF1673 PF07895.11 KEZ42268.1 - 0.28 10.8 2.9 0.15 11.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) A_deaminase PF00962.22 KEZ42269.1 - 3.3e-22 79.3 0.0 4.6e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans PF04082.18 KEZ42270.1 - 3.6e-17 62.3 0.1 6.1e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_4 PF13439.6 KEZ42270.1 - 0.02 14.9 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Transp_cyt_pur PF02133.15 KEZ42271.1 - 1.7e-95 320.4 43.4 2e-95 320.2 43.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 KEZ42272.1 - 1.6e-24 86.9 0.1 2.6e-24 86.3 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ42272.1 - 6.5e-24 84.3 0.0 1.4e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Alba PF01918.21 KEZ42272.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Alba p450 PF00067.22 KEZ42273.1 - 3.5e-53 181.0 0.0 2.2e-21 76.2 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 Zn_clus PF00172.18 KEZ42274.1 - 0.0054 16.8 3.3 0.0098 16.0 3.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ42275.1 - 1.4e-14 53.8 0.4 2e-14 53.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42275.1 - 0.0013 18.8 7.4 0.0025 17.9 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 KEZ42276.1 - 3e-23 82.6 0.0 4.8e-22 78.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ42276.1 - 1.4e-08 34.6 0.1 7.2e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEZ42276.1 - 0.0046 16.7 0.0 0.019 14.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 DUF1989 PF09347.10 KEZ42277.1 - 3.3e-51 173.2 0.0 5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 KEZ42277.1 - 4.1e-17 62.2 0.0 7.1e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KEZ42277.1 - 4.3e-07 29.8 0.0 9.4e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 KEZ42277.1 - 0.065 12.4 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 DUF2194 PF09960.9 KEZ42277.1 - 0.21 9.9 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) FAD_binding_3 PF01494.19 KEZ42278.1 - 7.6e-62 209.6 0.0 9.3e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ42278.1 - 2.7e-05 23.9 0.0 6.3e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ42278.1 - 3.4e-05 23.2 0.1 0.00053 19.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ42278.1 - 4.4e-05 22.5 0.0 6.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KEZ42278.1 - 0.00038 19.7 0.0 0.0024 17.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEZ42278.1 - 0.00048 19.4 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KEZ42278.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ42278.1 - 0.0021 18.6 0.1 0.0048 17.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ42278.1 - 0.0025 18.0 0.0 0.0078 16.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ42278.1 - 0.0036 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Phe_hydrox_dim PF07976.12 KEZ42278.1 - 0.0086 16.1 0.0 0.046 13.7 0.0 2.1 1 1 1 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KEZ42278.1 - 0.009 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KEZ42278.1 - 0.031 13.7 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KEZ42278.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KEZ42278.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 KEZ42279.1 - 5.5e-35 120.9 38.6 9.9e-35 120.1 36.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallothio_5 PF02067.15 KEZ42280.1 - 2.6 8.2 12.7 3.8 7.7 2.7 2.2 1 1 1 2 2 2 0 Metallothionein family 5 DUF4360 PF14273.6 KEZ42281.1 - 1.1e-52 178.6 2.0 1.2e-52 178.4 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PapA_C PF16911.5 KEZ42281.1 - 0.099 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus p450 PF00067.22 KEZ42282.1 - 4.6e-49 167.4 0.0 1.5e-46 159.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 RVT_thumb PF06817.14 KEZ42282.1 - 0.12 12.2 0.1 0.39 10.6 0.1 1.9 1 0 0 1 1 1 0 Reverse transcriptase thumb domain HET PF06985.11 KEZ42283.1 - 3.5e-26 92.3 3.3 1.1e-17 64.8 5.2 3.3 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Tannase PF07519.11 KEZ42284.1 - 1.7e-81 274.5 0.6 2.4e-81 274.0 0.6 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase HET PF06985.11 KEZ42284.1 - 1.4e-29 103.4 0.4 2.5e-29 102.5 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FPN1 PF06963.12 KEZ42284.1 - 3.2e-26 91.9 3.2 4.4e-26 91.4 3.2 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_S9 PF00326.21 KEZ42284.1 - 0.013 15.0 0.4 0.68 9.4 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Mntp PF02659.15 KEZ42284.1 - 0.12 12.1 1.9 0.24 11.2 1.9 1.4 1 0 0 1 1 1 0 Putative manganese efflux pump Methyltransf_2 PF00891.18 KEZ42287.1 - 4.5e-23 81.7 0.0 7.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KEZ42287.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain VIT PF08487.10 KEZ42289.1 - 1.8e-29 102.2 0.0 4.4e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KEZ42289.1 - 2.1e-27 96.0 0.0 4e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEZ42289.1 - 7.1e-11 42.7 0.0 1.2e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain APH PF01636.23 KEZ42289.1 - 1.6e-09 38.0 0.1 3.2e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family VWA_2 PF13519.6 KEZ42289.1 - 1.5e-07 32.0 0.0 3.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KEZ42289.1 - 1.3e-06 28.2 0.0 3.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Choline_kinase PF01633.20 KEZ42289.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cys_Met_Meta_PP PF01053.20 KEZ42290.1 - 6.3e-23 80.9 0.0 8.4e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KEZ42290.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ImcF-related_N PF14331.6 KEZ42290.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain MFS_1 PF07690.16 KEZ42291.1 - 1.4e-06 27.5 13.0 2.8e-06 26.5 13.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ42291.1 - 0.00026 20.0 2.2 0.00039 19.4 2.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 KEZ42291.1 - 0.0089 14.6 3.6 0.011 14.3 3.6 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Lipase_3 PF01764.25 KEZ42292.1 - 1.4e-17 63.9 0.1 4.2e-17 62.3 0.1 1.9 1 0 0 1 1 1 1 Lipase (class 3) MMR_HSR1 PF01926.23 KEZ42292.1 - 2.3e-05 24.4 0.0 5.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KEZ42292.1 - 0.0028 17.1 0.0 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEZ42292.1 - 0.0034 16.9 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Abhydrolase_6 PF12697.7 KEZ42292.1 - 0.0098 16.5 0.4 0.037 14.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 KEZ42292.1 - 0.02 15.0 0.3 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain IMS_C PF11799.8 KEZ42292.1 - 0.034 14.8 0.9 0.37 11.5 0.0 2.9 1 1 1 2 2 2 0 impB/mucB/samB family C-terminal domain DUF2974 PF11187.8 KEZ42292.1 - 0.046 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Dynamin_N PF00350.23 KEZ42292.1 - 0.096 12.7 0.0 0.4 10.7 0.0 1.9 1 1 0 1 1 1 0 Dynamin family Abhydrolase_5 PF12695.7 KEZ42292.1 - 0.18 11.6 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Alpha-L-AF_C PF06964.12 KEZ42293.1 - 8.7e-27 94.3 0.0 1.4e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KEZ42293.1 - 0.044 13.7 0.5 0.1 12.5 0.5 1.6 1 1 0 1 1 1 0 Glycoside hydrolase family 44 Sugar_tr PF00083.24 KEZ42294.1 - 8.1e-98 328.2 14.7 9.3e-98 328.0 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42294.1 - 4.4e-27 94.9 30.6 3.7e-19 68.9 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KEZ42295.1 - 8.8e-40 136.7 25.5 2.2e-24 86.0 9.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ42295.1 - 6.7e-09 35.1 0.6 6.7e-09 35.1 0.6 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter IMPDH PF00478.25 KEZ42296.1 - 1.5e-127 425.4 5.0 1.7e-127 425.2 5.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KEZ42296.1 - 5.9e-15 55.5 0.1 4.7e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KEZ42296.1 - 3e-09 36.4 1.0 5.8e-08 32.1 0.7 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KEZ42296.1 - 2.8e-08 33.5 1.5 0.0038 16.7 1.4 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 KEZ42296.1 - 0.00018 21.0 4.7 0.034 13.6 0.4 2.6 2 1 1 3 3 3 2 Histidine biosynthesis protein PK PF00224.21 KEZ42296.1 - 0.038 12.9 0.0 0.12 11.3 0.0 1.7 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain YpsA PF06908.11 KEZ42296.1 - 0.098 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 YspA SLOG family QRPTase_C PF01729.19 KEZ42296.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 KEZ42296.1 - 0.12 11.7 2.4 0.34 10.2 0.8 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_hydro_31 PF01055.26 KEZ42297.1 - 1.5e-146 489.1 1.2 1.9e-146 488.7 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KEZ42297.1 - 8.4e-27 93.7 0.0 1.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF4448 PF14610.6 KEZ42298.1 - 2.7e-39 134.9 0.3 3.8e-39 134.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CoA_binding_2 PF13380.6 KEZ42298.1 - 0.1 13.1 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Metallophos PF00149.28 KEZ42299.1 - 2e-09 38.3 0.4 6.7e-09 36.5 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5628 PF18621.1 KEZ42299.1 - 0.028 14.9 0.0 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5628) Peptidase_M1_N PF17900.1 KEZ42300.1 - 0.002 18.4 0.1 1 9.5 0.0 3.2 3 0 0 3 3 3 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KEZ42300.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M1 domain SAS4 PF15460.6 KEZ42301.1 - 1.5e-30 105.2 0.1 1.5e-30 105.2 0.1 2.7 4 0 0 4 4 4 1 Something about silencing, SAS, complex subunit 4 TFIIA PF03153.13 KEZ42301.1 - 0.96 9.4 29.4 0.93 9.4 16.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MreB_Mbl PF06723.13 KEZ42302.1 - 0.014 14.3 0.1 0.097 11.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Patatin PF01734.22 KEZ42303.1 - 1.8e-26 93.6 0.0 3e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Mito_carr PF00153.27 KEZ42304.1 - 3.4e-45 151.9 5.4 7.4e-17 61.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Polysacc_synt_4 PF04669.13 KEZ42306.1 - 4.5e-22 78.5 0.6 1.8e-20 73.3 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.9 KEZ42306.1 - 0.081 12.1 0.8 0.092 11.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DUF3506 PF12014.8 KEZ42307.1 - 2.8e-56 189.4 0.0 4.6e-56 188.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KEZ42307.1 - 9.6e-06 25.4 0.1 2.2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ42307.1 - 0.0028 17.5 0.1 0.0064 16.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF1769 PF08588.10 KEZ42308.1 - 4e-27 94.2 0.2 7.9e-27 93.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF3591 PF12157.8 KEZ42309.1 - 9.8e-166 551.8 0.0 1.3e-165 551.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KEZ42309.1 - 0.004 17.0 0.8 0.0089 15.9 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KEZ42309.1 - 0.0051 16.8 0.7 0.0087 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle D-ser_dehydrat PF14031.6 KEZ42310.1 - 3.9e-22 78.7 0.1 8.3e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KEZ42310.1 - 9.5e-10 38.5 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fasciclin PF02469.22 KEZ42310.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Fasciclin domain FAD_binding_2 PF00890.24 KEZ42311.1 - 8.7e-85 285.3 0.4 1.1e-84 285.0 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KEZ42311.1 - 2.6e-22 78.7 0.0 6.6e-21 74.2 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KEZ42311.1 - 1.6e-13 51.0 1.5 4.9e-13 49.4 1.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEZ42311.1 - 6.9e-10 38.9 0.9 3.1e-09 36.7 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ42311.1 - 7.9e-08 32.4 0.4 6.2e-07 29.6 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ42311.1 - 1.6e-07 30.8 0.6 1.1e-06 28.1 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ42311.1 - 2.6e-06 26.4 1.6 0.0063 15.3 0.2 3.2 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ42311.1 - 1.2e-05 24.8 0.1 0.097 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ42311.1 - 0.0003 20.1 1.9 0.023 13.9 0.6 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 KEZ42311.1 - 0.00095 18.5 0.8 0.002 17.5 0.8 1.5 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KEZ42311.1 - 0.002 17.3 3.0 0.25 10.4 0.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEZ42311.1 - 0.018 14.4 0.7 2.9 7.1 0.1 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KEZ42311.1 - 0.044 14.3 2.2 5 7.8 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ42311.1 - 0.063 12.6 0.4 0.12 11.6 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 KEZ42312.1 - 4.1e-125 418.2 15.0 4.8e-125 418.0 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ42312.1 - 1.1e-21 77.1 47.5 5.2e-20 71.7 23.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_1 PF00001.21 KEZ42312.1 - 0.47 9.7 4.9 1.6 8.0 0.3 2.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) MFS_1 PF07690.16 KEZ42314.1 - 2.3e-41 141.9 48.5 1.7e-39 135.7 47.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ42314.1 - 2.4e-09 36.2 15.8 3.4e-09 35.7 15.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEZ42314.1 - 6.3 5.0 14.6 2.5 6.3 3.1 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ribophorin_II PF05817.14 KEZ42315.1 - 6.3e-35 120.8 0.0 8.4e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PIG-F PF06699.11 KEZ42315.1 - 0.029 14.5 0.2 0.05 13.8 0.2 1.4 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F Peptidase_M28 PF04389.17 KEZ42316.1 - 8e-30 104.0 0.0 1.5e-29 103.1 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.21 KEZ42317.1 - 2.2e-16 60.3 0.2 2.2e-16 60.3 0.2 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Maf PF02545.14 KEZ42318.1 - 1.5e-48 164.8 0.0 1.7e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.26 KEZ42319.1 - 1.3e-07 31.5 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Amidohydro_1 PF01979.20 KEZ42320.1 - 5.7e-77 259.3 0.2 8.9e-76 255.4 0.2 2.1 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 KEZ42320.1 - 5.9e-54 181.6 2.6 7.9e-54 181.1 1.6 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 KEZ42320.1 - 2.3e-41 139.8 0.5 4.7e-41 138.8 0.1 1.7 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 KEZ42320.1 - 9.5e-40 134.9 0.0 2.9e-39 133.4 0.0 1.9 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KEZ42320.1 - 1e-06 28.5 0.1 8.7e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Ada3 PF10198.9 KEZ42321.1 - 3.8e-55 185.6 0.1 3.8e-55 185.6 0.1 3.0 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 LRIF1 PF15741.5 KEZ42321.1 - 0.014 14.0 8.0 0.02 13.5 8.0 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Presenilin PF01080.17 KEZ42321.1 - 1.4 7.6 9.3 2.1 7.0 9.3 1.2 1 0 0 1 1 1 0 Presenilin ECH_2 PF16113.5 KEZ42321.1 - 1.7 8.1 4.0 3.2 7.2 4.0 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase GREB1 PF15782.5 KEZ42321.1 - 4.1 4.4 4.9 5.4 4.0 4.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4064 PF13273.6 KEZ42322.1 - 0.13 12.6 1.6 4.5 7.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) LapA_dom PF06305.11 KEZ42322.1 - 0.22 11.4 0.5 0.56 10.0 0.5 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HMG_box PF00505.19 KEZ42323.1 - 1.4e-06 28.6 0.1 2.9e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEZ42323.1 - 0.00027 21.5 0.7 0.00057 20.4 0.1 2.0 2 0 0 2 2 2 1 HMG-box domain TruB_N PF01509.18 KEZ42323.1 - 0.056 13.8 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Het-C PF07217.11 KEZ42324.1 - 1.9e-236 786.0 0.0 1.9e-236 786.0 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 KEZ42324.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C Glyco_hydro_45 PF02015.16 KEZ42325.1 - 2.3e-77 259.6 18.4 2.7e-77 259.4 18.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF3419 PF11899.8 KEZ42326.1 - 1e-155 518.7 0.0 1.5e-155 518.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KEZ42326.1 - 1.1e-13 51.4 0.0 1.2e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42326.1 - 3.6e-08 34.0 0.0 7.7e-06 26.5 0.0 3.9 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42326.1 - 7.3e-07 29.8 0.0 0.00013 22.6 0.0 3.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42326.1 - 9e-07 29.6 0.0 2.9e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ42326.1 - 1.1e-06 28.2 0.0 0.0026 17.1 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KEZ42326.1 - 1.3e-05 25.0 0.0 3.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ42326.1 - 0.00013 21.7 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KEZ42326.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PROL5-SMR PF15621.6 KEZ42327.1 - 0.02 15.4 0.4 0.044 14.3 0.4 1.5 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family MSA-2c PF12238.8 KEZ42327.1 - 0.18 11.8 0.7 0.23 11.4 0.7 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Utp11 PF03998.13 KEZ42328.1 - 2.5e-53 181.5 21.8 1.7e-48 165.7 6.8 2.0 1 1 1 2 2 2 2 Utp11 protein SLATT_5 PF18160.1 KEZ42328.1 - 0.016 14.5 1.6 0.3 10.4 0.4 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Pes-10 PF07149.11 KEZ42328.1 - 1.6 7.7 7.9 2.2 7.2 7.9 1.2 1 0 0 1 1 1 0 Pes-10 TMEM119 PF15724.5 KEZ42328.1 - 2.5 8.1 3.9 3.4 7.6 3.9 1.2 1 0 0 1 1 1 0 TMEM119 family EMP24_GP25L PF01105.24 KEZ42328.1 - 4.2 7.3 6.0 0.67 9.9 2.1 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RRN3 PF05327.11 KEZ42328.1 - 5.8 5.3 6.6 7.7 4.9 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DAO PF01266.24 KEZ42329.1 - 1.9e-25 90.2 0.3 2.6e-25 89.7 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase APH PF01636.23 KEZ42329.1 - 8.8e-11 42.2 0.1 4e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KEZ42329.1 - 0.086 12.2 0.0 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 KEZ42329.1 - 0.1 12.2 0.0 11 5.5 0.1 2.2 2 0 0 2 2 2 0 RIO1 family Cmc1 PF08583.10 KEZ42330.1 - 9.4e-17 60.8 1.3 9.4e-17 60.8 1.3 1.9 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 KEZ42330.1 - 0.023 14.7 0.2 0.049 13.7 0.2 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 KEZ42330.1 - 0.029 14.5 1.0 0.4 10.9 1.0 2.2 1 1 0 1 1 1 0 CHCH domain EKLF_TAD1 PF16832.5 KEZ42330.1 - 0.25 11.3 1.2 0.44 10.4 1.2 1.4 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 DUF3128 PF11326.8 KEZ42330.1 - 1.2 9.6 9.4 2.3e+02 2.2 9.3 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) fn3 PF00041.21 KEZ42331.1 - 7.2e-09 35.9 0.1 2.1e-08 34.4 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Histidinol_dh PF00815.20 KEZ42332.1 - 4.6e-160 533.1 3.8 6.1e-160 532.7 3.8 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KEZ42332.1 - 1.9e-21 75.6 0.0 3.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KEZ42332.1 - 2e-13 50.6 0.3 6e-13 49.0 0.3 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Peptidase_M16 PF00675.20 KEZ42333.1 - 3.6e-55 186.0 0.4 1.4e-54 184.2 0.4 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEZ42333.1 - 8.7e-41 139.9 0.1 7.7e-40 136.8 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain RbsD_FucU PF05025.13 KEZ42333.1 - 0.14 12.6 0.1 0.49 10.8 0.1 2.0 2 0 0 2 2 2 0 RbsD / FucU transport protein family Raffinose_syn PF05691.12 KEZ42334.1 - 4.4e-53 180.2 0.4 2e-48 164.8 0.7 3.1 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Bromodomain PF00439.25 KEZ42335.1 - 9.8e-31 105.7 0.0 2.6e-14 53.1 0.0 3.0 3 0 0 3 3 3 2 Bromodomain RNA_pol_3_Rpc31 PF11705.8 KEZ42335.1 - 0.015 15.5 17.2 0.031 14.5 17.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 KEZ42335.1 - 0.027 12.7 14.5 0.038 12.2 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KEZ42335.1 - 0.17 11.4 17.8 0.34 10.5 17.8 1.5 1 0 0 1 1 1 0 PPP4R2 PRP38 PF03371.15 KEZ42335.1 - 0.2 11.5 0.4 0.4 10.5 0.4 1.5 1 0 0 1 1 1 0 PRP38 family DNA_pol_phi PF04931.13 KEZ42335.1 - 0.48 8.5 19.1 0.72 7.9 19.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tox-REase-2 PF15646.6 KEZ42335.1 - 0.51 10.5 3.2 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Restriction endonuclease fold toxin 2 NPR3 PF03666.13 KEZ42335.1 - 2 7.1 10.4 5 5.8 10.4 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NOA36 PF06524.12 KEZ42335.1 - 4.2 6.6 17.1 7.1 5.9 17.1 1.3 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.22 KEZ42335.1 - 6.1 6.0 6.2 9.3 5.4 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 KEZ42335.1 - 7.9 5.1 7.5 16 4.1 7.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CKS PF01111.19 KEZ42336.1 - 2.4e-34 117.4 1.3 3.6e-34 116.9 1.3 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.15 KEZ42337.1 - 5.9e-138 459.9 0.0 7.3e-138 459.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) But2 PF09792.9 KEZ42337.1 - 0.085 13.3 0.0 5.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain ACT_3 PF10000.9 KEZ42337.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ACT domain HVSL PF09749.9 KEZ42338.1 - 9.6e-80 267.5 0.0 1.1e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.11 KEZ42339.1 - 7.9e-08 33.1 0.8 1.2e-07 32.6 0.1 1.7 2 0 0 2 2 2 1 Pal1 cell morphology protein CPSF_A PF03178.15 KEZ42340.1 - 5.9e-83 278.9 0.0 1.5e-82 277.5 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KEZ42340.1 - 1.7e-15 56.7 0.0 6.4e-15 54.8 0.0 1.8 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Apt1 PF10351.9 KEZ42341.1 - 0.26 10.1 4.4 0.31 9.8 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 KEZ42341.1 - 0.74 9.7 7.0 0.89 9.4 7.0 1.1 1 0 0 1 1 1 0 SPX domain zf-HIT PF04438.16 KEZ42342.1 - 0.053 13.4 0.7 0.081 12.8 0.7 1.2 1 0 0 1 1 1 0 HIT zinc finger DUF4660 PF15559.6 KEZ42342.1 - 0.1 12.9 3.4 0.28 11.5 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) CEBP_ZZ PF16366.5 KEZ42342.1 - 0.14 12.4 2.8 0.23 11.7 2.8 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain GP24_25 PF17388.2 KEZ42342.1 - 0.14 12.1 0.6 0.23 11.4 0.6 1.2 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 zinc_ribbon_11 PF11682.8 KEZ42342.1 - 0.17 11.9 1.5 0.32 11.0 1.0 1.7 2 0 0 2 2 2 0 Probable zinc-ribbon Opy2 PF09463.10 KEZ42342.1 - 1.1 9.7 8.4 1.8 8.9 8.4 1.3 1 0 0 1 1 1 0 Opy2 protein zf-B_box PF00643.24 KEZ42342.1 - 2.9 8.1 5.8 17 5.7 5.8 2.0 1 1 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 KEZ42342.1 - 5.4 7.4 7.4 33 4.9 7.4 2.2 1 1 0 1 1 1 0 C1 domain Thg1C PF14413.6 KEZ42343.1 - 1.6e-13 50.9 5.5 6e-10 39.3 0.2 2.1 1 1 1 2 2 2 2 Thg1 C terminal domain Thg1 PF04446.12 KEZ42343.1 - 1.7e-05 24.8 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.32 KEZ42344.1 - 7.1e-08 33.0 2.5 0.033 15.0 0.0 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42344.1 - 0.00035 20.8 0.2 4.2 7.7 0.0 4.3 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KEZ42344.1 - 0.061 12.9 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain RNA_pol_Rpb1_1 PF04997.12 KEZ42345.1 - 5.4e-106 354.4 0.0 7.8e-106 353.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KEZ42345.1 - 1.6e-100 336.0 0.0 2.1e-100 335.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KEZ42345.1 - 1e-73 247.0 0.0 1.9e-73 246.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KEZ42345.1 - 2.5e-60 203.6 0.1 3.8e-60 203.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KEZ42345.1 - 1.3e-42 144.9 6.9 3.9e-42 143.4 6.7 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KEZ42345.1 - 1.8e-41 141.7 0.0 5.4e-41 140.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KEZ42345.1 - 1.1e-36 125.1 0.1 2.3e-36 124.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KEZ42345.1 - 3.2e-06 27.2 174.3 0.031 14.6 9.2 12.6 9 3 2 12 12 12 9 RNA polymerase Rpb1 C-terminal repeat HSP70 PF00012.20 KEZ42346.1 - 5.7e-229 761.3 4.1 6.4e-229 761.1 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ42346.1 - 1.2e-14 53.9 0.1 1.2e-13 50.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KEZ42346.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KEZ42346.1 - 0.045 12.7 0.4 0.24 10.4 0.1 2.1 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF726 PF05277.12 KEZ42347.1 - 3.3e-119 397.8 0.1 4.8e-119 397.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KEZ42347.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 KEZ42347.1 - 0.035 14.7 0.1 0.035 14.7 0.1 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family PE-PPE PF08237.11 KEZ42347.1 - 0.038 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain DUF1708 PF08101.11 KEZ42348.1 - 3e-175 583.5 0.0 4e-175 583.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.19 KEZ42350.1 - 3.8e-22 78.9 0.1 6.3e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily CDC45 PF02724.14 KEZ42350.1 - 0.035 12.4 2.5 0.04 12.2 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KEZ42350.1 - 0.9 8.8 11.7 1.2 8.4 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein Mito_carr PF00153.27 KEZ42351.1 - 7.6e-61 202.1 5.3 2.3e-22 78.7 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KEZ42352.1 - 1.3e-12 47.3 0.0 2.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42352.1 - 3e-06 27.2 9.6 3e-06 27.2 9.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 KEZ42353.1 - 1.7e-05 24.9 0.1 0.00017 21.7 0.1 2.3 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein PNP_UDP_1 PF01048.20 KEZ42354.1 - 1.7e-08 34.0 0.0 3.7e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily DUF4532 PF15046.6 KEZ42354.1 - 0.19 10.9 0.0 0.41 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4532) GTP_EFTU PF00009.27 KEZ42355.1 - 8.2e-45 152.7 0.0 1.4e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Mito_carr PF00153.27 KEZ42355.1 - 1.6e-39 133.7 0.3 3.3e-21 75.0 0.0 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein EFTUD2 PF16004.5 KEZ42355.1 - 1.9e-33 115.6 8.0 3.9e-33 114.6 8.0 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 KEZ42355.1 - 3.8e-21 74.9 0.0 1e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 KEZ42355.1 - 4.1e-21 75.0 0.0 8.2e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KEZ42355.1 - 1e-07 32.2 0.0 2.5e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KEZ42355.1 - 2.4e-06 27.6 0.0 5.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KEZ42355.1 - 0.00017 21.6 0.1 0.00032 20.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 KEZ42356.1 - 2.9e-90 302.2 0.9 4.5e-90 301.5 0.6 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ42356.1 - 8.1e-48 161.1 1.2 1.4e-47 160.4 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KEZ42356.1 - 1.3e-05 24.9 0.4 8e-05 22.3 0.4 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KEZ42356.1 - 0.0066 16.6 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 KEZ42356.1 - 0.82 9.6 4.9 4.5 7.2 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sin3a_C PF16879.5 KEZ42357.1 - 3.7e-73 246.7 2.3 5.5e-73 246.2 0.3 2.3 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KEZ42357.1 - 7.1e-42 141.3 9.9 4e-18 65.3 1.7 4.3 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KEZ42357.1 - 1.4e-38 130.9 0.1 4e-38 129.4 0.0 1.8 2 0 0 2 2 2 1 Sin3 family co-repressor Med3 PF11593.8 KEZ42357.1 - 0.036 13.2 1.9 0.074 12.2 1.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal IF4E PF01652.18 KEZ42358.1 - 1.2e-55 187.6 0.2 1.6e-55 187.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 KEZ42359.1 - 3.4e-74 250.0 0.0 4.3e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ42359.1 - 3.3e-12 47.2 0.3 7.6e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 KEZ42360.1 - 5.5e-29 100.3 2.4 9.7e-29 99.5 2.4 1.4 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 KEZ42360.1 - 0.45 11.0 4.3 0.88 10.1 1.1 2.6 1 1 2 3 3 3 0 Ribosomal proteins L26 eukaryotic, L24P archaeal PIP5K PF01504.18 KEZ42361.1 - 5.8e-33 114.3 0.1 5.8e-25 88.0 0.1 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KEZ42361.1 - 7e-23 81.0 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KEZ42361.1 - 2.6e-12 46.7 11.7 6.1e-12 45.5 11.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger VPS28 PF03997.12 KEZ42362.1 - 8.4e-68 227.8 0.0 9.9e-68 227.5 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Cep57_MT_bd PF06657.13 KEZ42363.1 - 3.1e-31 107.6 0.6 3.1e-31 107.6 0.6 5.9 3 1 5 8 8 8 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KEZ42363.1 - 9.3e-21 73.7 27.2 5.4e-15 55.2 8.7 6.4 3 1 3 6 6 6 3 Centrosome localisation domain of PPC89 OCD_Mu_crystall PF02423.15 KEZ42363.1 - 0.0065 15.4 0.8 0.02 13.9 0.0 2.0 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family IL17R_fnIII_D2 PF16578.5 KEZ42363.1 - 0.015 15.9 3.3 5.2 7.6 0.0 3.3 3 0 0 3 3 3 0 Interleukin 17 receptor D NPV_P10 PF05531.12 KEZ42363.1 - 0.61 10.6 22.1 22 5.6 0.2 7.3 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 KEZ42363.1 - 0.75 9.8 67.3 0.04 13.9 17.9 5.7 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 KEZ42363.1 - 1 9.9 68.6 1.2 9.6 3.3 8.3 5 2 2 7 7 7 0 Cell division protein ZapB APG6_N PF17675.1 KEZ42363.1 - 1.8 9.1 68.0 0.36 11.4 15.0 5.5 2 2 2 4 4 4 0 Apg6 coiled-coil region KASH_CCD PF14662.6 KEZ42363.1 - 5.3 6.8 67.2 0.014 15.2 16.5 5.6 2 1 1 4 4 4 0 Coiled-coil region of CCDC155 or KASH Glyco_hydro_76 PF03663.14 KEZ42364.1 - 5.6e-19 68.9 7.1 5e-18 65.8 7.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 MBOAT PF03062.19 KEZ42365.1 - 1.6e-52 179.0 15.3 3.2e-52 178.0 15.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family T4SS_CagC PF16943.5 KEZ42365.1 - 0.15 12.3 0.5 0.39 10.9 0.5 1.7 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system LRR19-TM PF15176.6 KEZ42366.1 - 0.73 9.9 0.0 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Peptidase_M56 PF05569.11 KEZ42366.1 - 0.77 8.9 6.4 2.4 7.3 0.5 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2070 PF09843.9 KEZ42366.1 - 8.3 4.6 12.1 12 4.0 12.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1523 PF07509.11 KEZ42366.1 - 9.3 5.6 9.6 0.27 10.6 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1523) UDPGP PF01704.18 KEZ42367.1 - 2.3e-54 184.6 0.0 4.2e-54 183.8 0.0 1.2 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Phytoreo_S7 PF07236.11 KEZ42367.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein DUF3052 PF11253.8 KEZ42367.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) NTP_transf_3 PF12804.7 KEZ42367.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 KEZ42367.1 - 0.22 11.3 0.0 0.49 10.2 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster tRNA-synt_1g PF09334.11 KEZ42368.1 - 7.2e-148 492.5 0.0 9.2e-148 492.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KEZ42368.1 - 2.6e-08 32.6 0.0 5.3e-05 21.7 0.0 3.1 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEZ42368.1 - 0.003 17.5 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA MbeD_MobD PF04899.12 KEZ42369.1 - 0.04 14.0 2.2 7 6.8 0.2 2.8 2 0 0 2 2 2 0 MbeD/MobD like Synaptobrevin PF00957.21 KEZ42369.1 - 0.38 10.6 2.5 1.3 8.9 0.1 2.5 3 0 0 3 3 3 0 Synaptobrevin F-box-like PF12937.7 KEZ42370.1 - 5.6e-14 51.8 0.3 1.2e-13 50.7 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ42370.1 - 1.9e-05 24.4 0.5 1.9e-05 24.4 0.5 2.3 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 KEZ42370.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 F-box Chromate_transp PF02417.15 KEZ42371.1 - 1.1e-56 191.3 30.2 1.3e-33 116.4 15.6 2.7 3 0 0 3 3 3 2 Chromate transporter Thioredoxin_4 PF13462.6 KEZ42373.1 - 1.4e-08 35.1 0.0 1.9e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KEZ42373.1 - 0.026 14.3 0.9 0.89 9.3 0.1 2.5 2 1 0 2 2 2 0 DSBA-like thioredoxin domain 2OG-FeII_Oxy PF03171.20 KEZ42374.1 - 0.013 16.0 0.0 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.12 KEZ42375.1 - 2.4e-48 164.4 0.2 3.7e-48 163.8 0.2 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KEZ42375.1 - 0.00079 19.6 0.0 0.0027 17.9 0.0 2.0 1 1 0 1 1 1 1 Fascin domain Frataxin_Cyay PF01491.16 KEZ42375.1 - 0.016 15.3 0.0 0.36 10.9 0.0 2.8 3 0 0 3 3 3 0 Frataxin-like domain Calmodulin_bind PF07887.11 KEZ42375.1 - 0.16 11.2 2.0 0.23 10.7 2.0 1.2 1 0 0 1 1 1 0 Calmodulin binding protein-like WD40 PF00400.32 KEZ42376.1 - 1.1e-10 41.9 0.3 0.019 15.8 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF3751 PF12571.8 KEZ42376.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage tail-collar fibre protein Sel1 PF08238.12 KEZ42377.1 - 1.3e-39 133.7 38.5 2.4e-05 24.8 0.1 13.2 13 0 0 13 13 13 10 Sel1 repeat Phage_holin_2_4 PF16082.5 KEZ42377.1 - 0.00036 20.2 0.1 0.0012 18.6 0.1 1.9 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like TPR_7 PF13176.6 KEZ42377.1 - 0.058 13.5 10.5 0.36 11.0 0.6 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ42377.1 - 0.11 12.8 17.7 1.3 9.4 1.4 7.7 7 2 2 9 9 9 0 Tetratricopeptide repeat SNAP PF14938.6 KEZ42377.1 - 0.42 10.0 4.9 0.39 10.1 0.1 3.2 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 KEZ42377.1 - 0.49 11.1 19.2 0.79 10.5 0.1 7.8 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ42377.1 - 0.82 9.6 16.5 1.1 9.2 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PX PF00787.24 KEZ42378.1 - 1.2e-22 80.0 0.0 1.7e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 PX domain CybS PF05328.12 KEZ42379.1 - 2.5e-47 159.9 0.0 3.1e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit tRNA-synt_1b PF00579.25 KEZ42380.1 - 1.8e-78 263.8 0.0 2.4e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KEZ42380.1 - 1.1e-45 154.3 0.0 2.1e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain NPR2 PF06218.11 KEZ42381.1 - 6.6e-122 407.4 0.0 1.1e-99 334.2 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 ubiquitin PF00240.23 KEZ42382.1 - 2.3e-20 72.1 0.1 3.4e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KEZ42382.1 - 1.1e-06 28.4 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain DUF2407 PF10302.9 KEZ42382.1 - 3.2e-05 24.4 0.0 5.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KEZ42382.1 - 4.2e-05 23.3 0.1 6.8e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KEZ42382.1 - 0.00086 19.4 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 KEZ42382.1 - 0.0056 16.6 7.7 0.5 10.3 1.6 2.7 2 0 0 2 2 2 2 STI1 domain HOIP-UBA PF16678.5 KEZ42382.1 - 0.036 14.1 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_2 PF14560.6 KEZ42382.1 - 0.13 12.8 0.6 0.41 11.1 0.6 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KEZ42382.1 - 0.31 11.1 0.3 13 5.9 0.3 2.3 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 KEZ42382.1 - 0.37 10.8 3.2 0.78 9.7 3.2 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain IBN_N PF03810.19 KEZ42383.1 - 7.6e-09 35.4 0.0 3.1e-08 33.4 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain NUC173 PF08161.12 KEZ42383.1 - 0.0037 17.0 0.3 1.2 8.8 0.1 3.2 3 0 0 3 3 3 2 NUC173 domain Xpo1 PF08389.12 KEZ42383.1 - 0.024 14.7 4.7 0.068 13.2 0.0 3.7 5 0 0 5 5 5 0 Exportin 1-like protein DUF5488 PF17590.2 KEZ42384.1 - 0.055 13.2 0.9 0.13 12.0 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Pribosyltran PF00156.27 KEZ42385.1 - 5.5e-14 52.0 0.0 8.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEZ42385.1 - 0.0031 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 KEZ42386.1 - 1.9e-108 363.3 0.0 2.5e-108 362.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1996 PF09362.10 KEZ42387.1 - 1.7e-82 277.0 0.8 2.1e-82 276.6 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) UPF0052 PF01933.18 KEZ42388.1 - 2.5e-62 210.8 0.0 3.5e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 GFO_IDH_MocA PF01408.22 KEZ42388.1 - 1.4e-19 71.1 0.0 2.7e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEZ42388.1 - 1.9e-05 24.7 0.0 7.2e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KEZ42388.1 - 0.00065 20.3 0.0 0.0021 18.7 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain RGS PF00615.19 KEZ42390.1 - 5.9e-06 26.5 0.0 0.00084 19.6 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain p450 PF00067.22 KEZ42391.1 - 5.9e-16 58.3 0.0 1.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Orf78 PF06024.12 KEZ42392.1 - 0.24 11.7 0.0 0.42 10.9 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_S41 PF03572.18 KEZ42393.1 - 2.2e-07 30.6 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 STIL_N PF15253.6 KEZ42393.1 - 0.086 11.8 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus FAA_hydrolase PF01557.18 KEZ42394.1 - 4.1e-59 199.9 0.0 5.7e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GMC_oxred_N PF00732.19 KEZ42395.1 - 3.6e-48 164.4 0.0 1e-47 163.0 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ42395.1 - 1.8e-30 106.4 0.0 3.4e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ42395.1 - 1.2e-05 24.6 0.1 0.09 11.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KEZ42395.1 - 0.0013 18.0 0.0 0.068 12.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ42395.1 - 0.0079 15.8 0.5 1.2 8.6 0.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ42395.1 - 0.022 15.0 0.5 0.065 13.5 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ42395.1 - 0.048 12.9 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ42395.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KEZ42395.1 - 0.16 10.7 0.0 13 4.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Candida_ALS PF05792.13 KEZ42396.1 - 1.7e-06 28.5 352.9 0.04 14.5 10.1 21.9 21 1 0 21 21 21 16 Candida agglutinin-like (ALS) SepZ PF06066.11 KEZ42396.1 - 1.8 8.8 7.6 14 5.9 0.1 3.3 3 0 0 3 3 3 0 SepZ Glyco_hydro_61 PF03443.14 KEZ42398.1 - 2e-56 191.2 0.1 2.3e-56 191.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAPRTase PF04095.16 KEZ42399.1 - 6.3e-58 196.2 0.5 1.9e-54 184.8 0.5 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KEZ42399.1 - 9.4e-36 123.0 0.1 1.9e-35 122.0 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WD40 PF00400.32 KEZ42400.1 - 6.9e-10 39.4 8.2 1.2 10.2 0.0 8.7 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42400.1 - 2.1e-06 27.9 0.1 0.39 11.0 0.0 5.7 4 3 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ42400.1 - 0.00016 20.8 0.0 0.021 13.8 0.0 3.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEZ42400.1 - 0.00023 21.0 0.4 1 9.4 0.1 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IMUP PF15761.5 KEZ42400.1 - 2.7 8.7 7.8 2.1 9.1 4.6 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Rad4 PF03835.15 KEZ42401.1 - 3.3e-14 52.8 2.8 6.6e-14 51.8 2.8 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KEZ42401.1 - 7.6e-11 42.5 2.3 1.6e-10 41.4 2.3 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily HXXSHH PF07586.11 KEZ42402.1 - 0.055 13.0 0.1 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) RGCC PF15151.6 KEZ42402.1 - 0.46 10.7 3.1 0.46 10.7 2.6 1.3 1 1 0 1 1 1 0 Response gene to complement 32 protein family Memo PF01875.17 KEZ42403.1 - 6.4e-73 245.2 0.0 7.4e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Syntaxin PF00804.25 KEZ42404.1 - 2.7e-21 76.2 11.9 3.3e-21 75.9 7.8 2.4 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 KEZ42404.1 - 7.9e-11 41.8 1.6 4e-10 39.5 1.6 2.3 1 0 0 1 1 1 1 SNARE domain MCU PF04678.13 KEZ42404.1 - 0.016 15.3 6.9 0.037 14.1 2.2 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4834 PF16118.5 KEZ42404.1 - 0.038 14.9 0.1 0.038 14.9 0.1 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) AA_permease_2 PF13520.6 KEZ42404.1 - 0.082 11.7 1.4 0.1 11.4 1.4 1.1 1 0 0 1 1 1 0 Amino acid permease MARVEL PF01284.23 KEZ42404.1 - 0.096 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2951 PF11166.8 KEZ42404.1 - 0.58 10.4 5.7 0.38 11.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Mod_r PF07200.13 KEZ42404.1 - 1.8 8.6 7.5 0.93 9.6 3.1 2.3 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Synaptobrevin PF00957.21 KEZ42404.1 - 2.4 8.0 10.5 11 5.9 10.5 2.2 1 1 0 1 1 1 0 Synaptobrevin DUF5446 PF17522.2 KEZ42404.1 - 4.4 7.6 6.8 1.6 8.9 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5446) zf-CpG_bind_C PF12269.8 KEZ42404.1 - 6.4 6.5 9.6 2.7 7.7 0.4 2.3 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Rhodanese PF00581.20 KEZ42405.1 - 2.8e-17 63.2 0.0 1.8e-10 41.2 0.0 2.5 2 1 1 3 3 3 2 Rhodanese-like domain Ribosomal_S5 PF00333.20 KEZ42406.1 - 2.2e-27 94.8 1.0 4.8e-27 93.7 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KEZ42406.1 - 4.7e-23 80.4 0.0 8.1e-23 79.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 KEZ42406.1 - 1.1 9.9 14.2 2.6 8.6 14.2 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ELM2 PF01448.24 KEZ42408.1 - 0.03 15.1 2.2 0.092 13.5 0.6 2.7 2 0 0 2 2 2 0 ELM2 domain gag-asp_proteas PF13975.6 KEZ42408.1 - 0.19 12.3 0.0 0.43 11.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Myc_N PF01056.18 KEZ42408.1 - 1.6 8.6 7.7 0.51 10.2 3.3 2.0 2 0 0 2 2 2 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 KEZ42408.1 - 3.2 8.2 9.2 0.38 11.2 3.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SDA1 PF05285.12 KEZ42408.1 - 7.6 5.9 15.9 2.1 7.7 11.0 2.1 2 0 0 2 2 2 0 SDA1 Casc1_N PF15927.5 KEZ42408.1 - 8.7 6.0 18.4 0.053 13.2 8.7 2.1 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Cyclin_N PF00134.23 KEZ42409.1 - 1.9e-38 131.1 0.1 3.6e-38 130.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KEZ42409.1 - 9.8e-11 41.8 0.2 2.3e-10 40.6 0.2 1.6 1 1 0 1 1 1 1 Cyclin, C-terminal domain P_C10 PF14974.6 KEZ42409.1 - 0.069 13.3 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein C10 DUF1713 PF08213.11 KEZ42410.1 - 8e-05 22.5 24.7 8e-05 22.5 24.7 2.4 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KEZ42410.1 - 0.009 16.7 0.0 0.026 15.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial protein Pet20 FAD_binding_8 PF08022.12 KEZ42411.1 - 2.6e-22 79.0 0.0 4.9e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KEZ42411.1 - 3.3e-22 79.3 0.0 5.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KEZ42411.1 - 1.9e-20 73.2 10.2 1.9e-20 73.2 10.2 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KEZ42411.1 - 0.087 13.5 0.0 3.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEZ42411.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain GNAT_acetyltr_2 PF13718.6 KEZ42412.1 - 5.7e-97 323.6 0.0 1.1e-96 322.7 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KEZ42412.1 - 5.4e-83 278.3 0.0 8.7e-83 277.6 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KEZ42412.1 - 3.3e-65 219.3 0.0 1.1e-64 217.5 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KEZ42412.1 - 3.7e-34 116.5 0.1 9e-34 115.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KEZ42412.1 - 5.2e-07 29.6 0.2 0.0039 16.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KEZ42412.1 - 0.00023 21.5 0.0 0.038 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 KEZ42412.1 - 0.08 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain Myosin_head PF00063.21 KEZ42413.1 - 1.7e-238 793.3 2.0 2e-238 793.0 2.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KEZ42413.1 - 2e-46 158.0 0.0 4.9e-46 156.8 0.0 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KEZ42413.1 - 1.3e-13 50.3 0.2 3e-13 49.2 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ42413.1 - 7.5e-10 38.5 0.1 5.5e-09 35.8 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KEZ42413.1 - 8.2e-09 35.0 0.0 1.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KEZ42413.1 - 0.0044 16.7 10.0 0.17 11.8 2.4 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 KEZ42413.1 - 0.024 14.2 0.3 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KEZ42413.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain hSH3 PF14603.6 KEZ42413.1 - 0.074 13.5 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 Helically-extended SH3 domain SepF PF04472.12 KEZ42413.1 - 0.088 13.1 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Cell division protein SepF AAA_16 PF13191.6 KEZ42413.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KEZ42413.1 - 0.13 12.1 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF4913 PF16259.5 KEZ42413.1 - 0.17 12.0 1.1 0.42 10.7 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Raptor_N PF14538.6 KEZ42414.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain HNH_2 PF13391.6 KEZ42415.1 - 4.4e-09 36.3 1.2 1.1e-08 35.0 0.4 2.2 2 1 0 2 2 2 1 HNH endonuclease Pkinase PF00069.25 KEZ42416.1 - 5e-09 35.9 0.0 1.2e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain SWIRM-assoc_2 PF16496.5 KEZ42416.1 - 0.0064 15.4 0.1 0.0064 15.4 0.1 3.8 4 1 1 5 5 5 1 SWIRM-associated domain at the N-terminal Pkinase_Tyr PF07714.17 KEZ42416.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PTCB-BRCT PF12738.7 KEZ42416.1 - 0.043 13.8 0.8 0.12 12.3 0.8 1.8 1 1 0 1 1 1 0 twin BRCT domain AT_hook PF02178.19 KEZ42416.1 - 1.8 8.7 17.3 0.62 10.1 2.6 4.1 3 0 0 3 3 3 0 AT hook motif MpPF1 PF07668.11 KEZ42417.1 - 0.11 11.7 0.4 0.16 11.2 0.4 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 DAHP_synth_2 PF01474.16 KEZ42418.1 - 6.9e-199 660.8 0.0 7.8e-199 660.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Aldose_epim PF01263.20 KEZ42419.1 - 2.6e-36 125.5 0.0 3.1e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.8 KEZ42420.1 - 1e-129 432.8 0.6 5.5e-129 430.4 0.0 2.1 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Chromo PF00385.24 KEZ42421.1 - 1.2e-18 66.7 2.0 2e-18 66.0 2.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PQ-loop PF04193.14 KEZ42422.1 - 2.5e-24 84.8 2.1 8e-14 51.2 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat tRNA-synt_2 PF00152.20 KEZ42423.1 - 5.4e-78 262.2 0.0 6.9e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEZ42423.1 - 0.033 14.2 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ANTH PF07651.16 KEZ42424.1 - 1.9e-69 233.8 0.3 2.7e-69 233.2 0.3 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KEZ42424.1 - 1.9e-07 31.2 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain CS PF04969.16 KEZ42425.1 - 1.1e-17 64.8 0.2 2.5e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 CS domain Glyco_hydro_3_C PF01915.22 KEZ42426.1 - 1.4e-64 217.9 0.0 3.5e-64 216.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ42426.1 - 4.2e-50 170.9 0.0 7e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 KEZ42426.1 - 3e-25 88.7 0.0 5.6e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 KEZ42426.1 - 1.1e-22 79.9 0.0 2.6e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Cation_efflux PF01545.21 KEZ42427.1 - 6.6e-29 101.1 6.7 1.9e-28 99.6 6.7 1.7 1 1 0 1 1 1 1 Cation efflux family Peptidase_M66 PF10462.9 KEZ42427.1 - 0.02 13.9 0.9 0.032 13.2 0.9 1.3 1 0 0 1 1 1 0 Peptidase M66 MFS_1 PF07690.16 KEZ42428.1 - 3.5e-35 121.6 78.6 3.9e-31 108.3 31.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ42428.1 - 5.7e-15 54.8 32.8 9.5e-15 54.0 29.6 2.1 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEZ42428.1 - 8.8e-10 38.0 15.9 8.8e-10 38.0 15.9 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter Rad1 PF02144.16 KEZ42429.1 - 2.8e-68 229.9 0.0 3.3e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 KEZ42430.1 - 4e-17 62.2 8.7 4.6e-17 62.0 8.7 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF3096 PF11295.8 KEZ42430.1 - 0.051 13.2 0.8 0.051 13.2 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) Bromodomain PF00439.25 KEZ42431.1 - 7.6e-26 90.0 0.2 2.1e-25 88.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KEZ42431.1 - 6.6e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ42431.1 - 7.1e-07 29.2 0.3 1.7e-06 28.0 0.2 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ42431.1 - 0.0003 21.2 0.4 0.00062 20.2 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ42431.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Trypan_PARP PF05887.11 KEZ42432.1 - 0.23 11.4 13.0 0.94 9.5 13.0 2.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KEZ42432.1 - 1.3 8.2 4.3 2.2 7.4 4.3 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Ribosomal_L18A PF01775.17 KEZ42433.1 - 4.4e-55 185.0 0.3 6.2e-55 184.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 KEZ42434.1 - 5.9e-14 52.5 0.0 4.6e-13 49.6 0.0 2.4 3 0 0 3 3 3 1 PCI domain DUF2764 PF10962.8 KEZ42434.1 - 0.1 12.0 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2764) BTB PF00651.31 KEZ42435.1 - 7.8e-08 32.5 0.1 2.6e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Fungal_trans PF04082.18 KEZ42436.1 - 1.8e-12 46.9 1.0 4.1e-12 45.7 1.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Homeobox_KN PF05920.11 KEZ42437.1 - 3.2e-22 78.1 0.6 8.3e-22 76.8 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KEZ42437.1 - 1.2e-08 34.7 1.4 2.6e-08 33.6 1.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 KEZ42438.1 - 5.8e-08 32.5 0.1 2.5e-07 30.4 0.1 2.1 1 0 0 1 1 1 1 Homeodomain Rhodanese PF00581.20 KEZ42438.1 - 1.7e-07 31.7 0.0 6e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain OmpH PF03938.14 KEZ42438.1 - 0.65 10.3 2.6 1.4 9.3 2.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PIG-X PF08320.12 KEZ42439.1 - 8.4e-65 218.6 0.1 1.2e-64 218.2 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 FeoB_C PF07664.12 KEZ42439.1 - 0.035 13.8 1.3 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Cas1_AcylT PF07779.12 KEZ42440.1 - 3.4e-69 234.0 5.7 5.3e-69 233.4 5.7 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KEZ42440.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF4149 PF13664.6 KEZ42440.1 - 0.19 12.1 0.1 0.19 12.1 0.1 4.0 2 1 3 5 5 5 0 Domain of unknown function (DUF4149) BofA PF07441.11 KEZ42440.1 - 0.77 10.0 5.3 0.47 10.7 0.1 3.3 3 0 0 3 3 3 0 SigmaK-factor processing regulatory protein BofA YpmT PF17431.2 KEZ42440.1 - 5 7.2 5.3 2 8.5 0.8 2.6 3 0 0 3 3 3 0 Uncharacterized YmpT-like DUF2834 PF11196.8 KEZ42441.1 - 0.00024 21.4 7.3 0.006 16.9 0.1 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF2834) RBR PF17208.3 KEZ42441.1 - 0.21 12.3 9.3 0.48 11.2 9.3 1.6 1 0 0 1 1 1 0 RNA binding Region DUF908 PF06012.12 KEZ42441.1 - 3.2 7.1 3.7 22 4.3 3.7 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) Arf PF00025.21 KEZ42442.1 - 6.7e-39 133.1 0.1 2e-24 86.0 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 KEZ42442.1 - 3.3e-13 49.5 0.0 2e-08 33.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KEZ42442.1 - 6.1e-09 36.1 0.0 1.7e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KEZ42442.1 - 9.7e-08 31.6 0.0 1.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KEZ42442.1 - 1.4e-07 31.3 0.0 0.00077 19.1 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 KEZ42442.1 - 7.4e-07 28.8 0.1 9.7e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KEZ42442.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEZ42442.1 - 0.0047 16.5 0.1 0.018 14.6 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RNase_PH PF01138.21 KEZ42443.1 - 6.1e-24 85.0 0.0 8.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEZ42443.1 - 1.2e-10 41.2 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 KEZ42444.1 - 1.9e-80 270.2 26.3 2.2e-80 270.0 26.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 KEZ42444.1 - 1.9 6.7 22.6 2.3 6.4 22.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 KEZ42444.1 - 2.5 6.8 10.7 3 6.5 10.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PGA2 PF07543.12 KEZ42444.1 - 2.9 7.9 20.4 6 6.8 20.4 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 FGGY_C PF02782.16 KEZ42445.1 - 1.2e-25 90.5 0.0 3.4e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KEZ42445.1 - 4.6e-16 59.1 0.0 1.4e-12 47.7 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 KEZ42446.1 - 3.3e-46 157.5 9.3 4.1e-46 157.2 9.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEZ42446.1 - 0.00019 21.5 0.6 0.00057 20.0 0.0 2.1 2 1 0 2 2 2 1 Dimerisation domain of Zinc Transporter HCV_env PF01539.17 KEZ42446.1 - 0.53 9.9 4.5 0.34 10.6 1.9 1.8 1 1 1 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 MFS_1 PF07690.16 KEZ42447.1 - 1.9e-18 66.6 33.7 1.9e-18 66.6 33.7 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily DoxD PF04173.13 KEZ42447.1 - 0.08 12.8 3.8 0.21 11.5 3.8 1.7 1 0 0 1 1 1 0 TQO small subunit DoxD DUF3810 PF12725.7 KEZ42447.1 - 0.12 11.7 0.0 0.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF3649 PF12365.8 KEZ42447.1 - 0.13 12.0 3.1 0.19 11.5 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) PQ-loop PF04193.14 KEZ42448.1 - 6.7e-40 134.7 19.3 1e-20 73.3 2.4 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KEZ42448.1 - 1.8 9.4 5.5 29 5.5 0.1 2.8 3 1 1 4 4 4 0 ER lumen protein retaining receptor TIP41 PF04176.13 KEZ42449.1 - 3.7e-65 218.6 0.1 4.6e-65 218.3 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family ERM PF00769.19 KEZ42450.1 - 0.0096 15.8 13.1 0.016 15.0 13.1 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Bacillus_HBL PF05791.11 KEZ42450.1 - 0.014 15.3 1.9 0.025 14.4 1.2 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Prominin PF05478.11 KEZ42450.1 - 0.024 12.6 3.8 0.035 12.1 3.8 1.1 1 0 0 1 1 1 0 Prominin GAS PF13851.6 KEZ42450.1 - 0.025 13.9 12.5 0.046 13.1 12.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 KEZ42450.1 - 0.1 13.1 20.9 0.028 15.0 16.5 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 KEZ42450.1 - 0.11 11.8 9.9 0.2 10.9 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KEZ42450.1 - 0.14 12.2 17.9 0.41 10.7 17.8 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KEZ42450.1 - 0.14 11.0 13.4 0.24 10.2 13.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 KEZ42450.1 - 0.21 10.6 8.2 0.35 9.9 8.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CAGE1 PF15066.6 KEZ42450.1 - 0.24 10.0 13.6 0.35 9.5 13.6 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family CENP-H PF05837.12 KEZ42450.1 - 0.39 11.2 16.7 0.23 11.9 13.4 2.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) ATG16 PF08614.11 KEZ42450.1 - 0.41 10.8 20.6 0.4 10.9 14.6 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.6 KEZ42450.1 - 0.71 10.0 13.2 3.9 7.6 13.2 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Jnk-SapK_ap_N PF09744.9 KEZ42450.1 - 0.96 9.7 15.5 2 8.6 15.5 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ING PF12998.7 KEZ42450.1 - 1.1 9.9 8.2 3.3 8.3 7.7 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2968 PF11180.8 KEZ42450.1 - 1.3 8.7 11.8 0.32 10.6 8.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FliJ PF02050.16 KEZ42450.1 - 1.5 9.1 19.2 0.4 10.9 15.6 1.9 2 1 0 2 2 2 0 Flagellar FliJ protein FapA PF03961.13 KEZ42450.1 - 1.5 7.3 6.6 2.5 6.6 6.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 KEZ42450.1 - 2.2 7.8 9.0 3 7.4 7.0 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pkinase PF00069.25 KEZ42451.1 - 8.7e-72 241.6 0.0 1.1e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42451.1 - 4.1e-44 150.8 0.0 5.4e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ42451.1 - 3e-07 30.1 0.0 1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEZ42451.1 - 0.00048 19.5 0.1 0.00089 18.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KEZ42451.1 - 0.0048 16.5 0.0 0.046 13.3 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KEZ42451.1 - 0.021 13.8 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KEZ42451.1 - 0.056 13.4 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KEZ42451.1 - 0.071 12.6 0.1 0.17 11.3 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KEZ42451.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 KEZ42451.1 - 0.26 10.3 0.0 0.56 9.2 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M76 PF09768.9 KEZ42452.1 - 7.4e-66 221.1 0.5 9.3e-66 220.8 0.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KEZ42452.1 - 0.0018 18.1 0.4 0.0038 17.1 0.3 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KEZ42452.1 - 0.029 14.7 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 Effector protein Peptidase_M90 PF06167.12 KEZ42452.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 AA_kinase PF00696.28 KEZ42453.1 - 1.1e-40 139.7 1.7 1.5e-40 139.3 1.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KEZ42453.1 - 1.3e-15 57.1 0.4 6.1e-15 54.9 0.1 2.3 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 KEZ42454.1 - 1.3e-26 92.6 0.0 2.2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 KEZ42454.1 - 1.9e-25 89.2 0.1 2.7e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KEZ42454.1 - 0.071 13.1 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 PUA domain DUF3517 PF12030.8 KEZ42456.1 - 6.6e-94 314.6 0.0 4.9e-93 311.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 KEZ42456.1 - 6.8e-38 130.6 0.1 1.2e-37 129.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ42456.1 - 2.3e-17 63.6 0.0 1.6e-16 60.8 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pox_A3L PF05288.11 KEZ42456.1 - 0.18 11.8 1.5 0.99 9.4 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A3L Protein HEAT PF02985.22 KEZ42458.1 - 0.0033 17.5 0.1 0.22 11.9 0.0 3.8 2 0 0 2 2 2 1 HEAT repeat Orbi_NS3 PF01616.16 KEZ42458.1 - 0.031 14.0 0.3 0.065 12.9 0.3 1.5 1 0 0 1 1 1 0 Orbivirus NS3 HEAT_2 PF13646.6 KEZ42458.1 - 0.044 14.2 0.2 5.2 7.5 0.0 4.5 6 0 0 6 6 6 0 HEAT repeats V-ATPase_H_C PF11698.8 KEZ42458.1 - 0.12 12.5 0.0 7.5 6.7 0.0 3.2 2 1 1 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.6 KEZ42458.1 - 0.36 11.4 1.4 15 6.2 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat DUF1749 PF08538.10 KEZ42459.1 - 1.9e-75 253.7 0.0 2.2e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KEZ42459.1 - 2.9e-06 28.1 0.0 3.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ42459.1 - 9.7e-05 21.7 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ42459.1 - 0.00032 20.4 0.0 0.0016 18.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_7 PF12715.7 KEZ42459.1 - 0.087 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase family LIDHydrolase PF10230.9 KEZ42459.1 - 0.24 10.9 0.3 0.74 9.3 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase p450 PF00067.22 KEZ42460.1 - 1e-46 159.7 0.0 1.9e-40 139.0 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 SPX PF03105.19 KEZ42461.1 - 0.06 13.2 6.3 0.072 13.0 6.3 1.2 1 0 0 1 1 1 0 SPX domain Tim17 PF02466.19 KEZ42463.1 - 5.4e-24 84.7 4.2 1.1e-23 83.7 3.5 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family HTH_psq PF05225.16 KEZ42463.1 - 0.032 14.0 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_28 PF13518.6 KEZ42463.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain NUDIX PF00293.28 KEZ42464.1 - 3.4e-16 59.5 0.1 6.1e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KEZ42464.1 - 1.4e-10 41.8 0.0 3.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KEZ42464.1 - 4e-07 29.6 1.8 7.2e-07 28.8 1.8 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF5321 PF17254.2 KEZ42465.1 - 2e-48 163.9 0.1 2.4e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Trypan_PARP PF05887.11 KEZ42465.1 - 0.0015 18.5 0.2 0.0022 18.0 0.2 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF5470 PF17564.2 KEZ42465.1 - 0.037 14.2 0.8 0.066 13.4 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Peptidase_C50 PF03568.17 KEZ42466.1 - 3.2e-160 533.6 0.0 3.5e-159 530.1 0.0 2.3 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KEZ42466.1 - 6.6e-06 26.3 12.4 0.11 12.8 0.3 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat CHAT PF12770.7 KEZ42466.1 - 8.9e-05 22.0 0.2 0.0019 17.7 0.0 2.8 3 0 0 3 3 3 1 CHAT domain TPR_2 PF07719.17 KEZ42466.1 - 0.27 11.4 6.0 69 3.9 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ42466.1 - 0.57 10.5 3.5 39 4.8 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KEZ42467.1 - 7.6e-24 84.2 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42467.1 - 2.1e-09 37.4 10.9 3.4e-09 36.7 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kri1 PF05178.12 KEZ42468.1 - 1.4e-27 96.2 24.9 1.4e-27 96.2 24.9 6.4 6 3 2 8 8 8 1 KRI1-like family Kri1_C PF12936.7 KEZ42468.1 - 5.4e-25 87.4 0.1 5.4e-25 87.4 0.1 5.3 5 1 1 6 6 6 1 KRI1-like family C-terminal Ras PF00071.22 KEZ42469.1 - 2.1e-58 196.5 0.0 2.5e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ42469.1 - 3.1e-34 117.8 0.0 4.6e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ42469.1 - 3.3e-15 56.0 0.0 4e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEZ42469.1 - 4.7e-07 29.4 0.0 5.7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KEZ42469.1 - 5e-06 26.2 0.0 7.8e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEZ42469.1 - 6.1e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ42469.1 - 0.00073 19.9 0.0 0.0011 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ42469.1 - 0.015 15.2 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase zf-RING_6 PF14835.6 KEZ42470.1 - 0.0061 16.4 6.9 0.0096 15.8 6.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KEZ42470.1 - 0.012 15.4 12.1 0.019 14.8 12.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 KEZ42471.1 - 7.2e-68 228.8 1.9 7.2e-67 225.5 1.9 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42471.1 - 3.7e-53 180.5 0.1 3.7e-53 180.5 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KEZ42471.1 - 5.6e-24 84.3 0.0 1.4e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KEZ42471.1 - 3.2e-07 29.9 0.0 5.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEZ42471.1 - 2.4e-06 26.6 0.4 6e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase PH_11 PF15413.6 KEZ42471.1 - 3.3e-05 24.2 0.0 0.00015 22.2 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 KEZ42471.1 - 0.005 16.8 0.1 0.058 13.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEZ42471.1 - 0.048 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4612 PF15389.6 KEZ42471.1 - 0.053 14.6 1.7 0.15 13.1 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) KIND PF16474.5 KEZ42471.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain PH PF00169.29 KEZ42471.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 KEZ42471.1 - 1.4 7.8 5.9 0.083 11.8 0.2 1.8 2 1 0 2 2 2 0 Haspin like kinase domain Lyase_1 PF00206.20 KEZ42472.1 - 8e-62 209.4 0.1 5.7e-50 170.5 0.0 2.1 1 1 1 2 2 2 2 Lyase ASL_C2 PF14698.6 KEZ42472.1 - 3.7e-23 82.0 0.2 8.6e-23 80.9 0.2 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF4360 PF14273.6 KEZ42473.1 - 2.4e-46 157.8 0.0 2.8e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-CCCH PF00642.24 KEZ42474.1 - 0.035 14.0 0.7 0.035 14.0 0.7 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HypA PF01155.19 KEZ42474.1 - 0.38 10.8 1.6 0.82 9.7 1.6 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HET PF06985.11 KEZ42475.1 - 2.1e-09 37.9 12.2 2.6e-07 31.1 6.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_28 PF13521.6 KEZ42475.1 - 0.063 13.5 0.1 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KEZ42476.1 - 3.7e-18 66.1 1.9 2.1e-17 63.7 1.9 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEZ42476.1 - 2.6e-07 30.2 0.0 1.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region AAA_15 PF13175.6 KEZ42476.1 - 0.0033 17.2 0.1 0.0063 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain CobT PF06213.12 KEZ42476.1 - 0.014 14.8 13.6 0.025 14.0 13.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GED PF02212.18 KEZ42476.1 - 0.026 14.7 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 Dynamin GTPase effector domain Merozoite_SPAM PF07133.11 KEZ42476.1 - 0.035 14.1 27.6 0.078 13.0 27.6 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) MMR_HSR1 PF01926.23 KEZ42476.1 - 0.037 14.1 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ42476.1 - 0.048 14.0 0.1 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SDA1 PF05285.12 KEZ42476.1 - 0.057 12.8 17.7 0.092 12.2 17.7 1.2 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 KEZ42476.1 - 0.16 12.3 8.4 0.28 11.5 8.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MRNIP PF15749.5 KEZ42476.1 - 0.35 11.6 4.4 1.9 9.3 4.5 2.1 2 0 0 2 2 2 0 MRN-interacting protein AAA_23 PF13476.6 KEZ42476.1 - 0.4 11.2 0.0 0.4 11.2 0.0 2.5 1 1 0 2 2 1 0 AAA domain CDC45 PF02724.14 KEZ42476.1 - 0.66 8.2 17.6 0.99 7.6 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 KEZ42476.1 - 0.76 7.8 26.6 1.2 7.2 26.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 KEZ42476.1 - 1 8.3 18.0 1.6 7.6 18.0 1.2 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.11 KEZ42476.1 - 1.2 7.6 13.8 0.32 9.5 10.2 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.12 KEZ42476.1 - 1.3 8.8 9.2 2.3 8.0 9.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 KEZ42476.1 - 1.7 6.8 22.0 3.3 5.8 22.0 1.3 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KEZ42476.1 - 1.8 6.9 22.1 2.7 6.3 22.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Pes-10 PF07149.11 KEZ42476.1 - 2.1 7.3 18.4 1.4 7.9 15.0 2.1 2 0 0 2 2 2 0 Pes-10 Raftlin PF15250.6 KEZ42476.1 - 2.1 7.0 5.5 3.3 6.4 5.5 1.2 1 0 0 1 1 1 0 Raftlin TFIIF_alpha PF05793.12 KEZ42476.1 - 2.3 6.7 20.2 4.4 5.8 20.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.13 KEZ42476.1 - 3.1 6.1 4.3 4.4 5.5 4.3 1.1 1 0 0 1 1 1 0 Menin TFB6 PF17110.5 KEZ42476.1 - 5.1 6.8 8.4 10 5.8 8.4 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 KEZ42476.1 - 7.4 5.7 9.2 13 4.9 9.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 KEZ42476.1 - 8.7 5.0 6.0 13 4.4 6.0 1.2 1 0 0 1 1 1 0 Presenilin LysM PF01476.20 KEZ42477.1 - 9.9e-14 51.1 2.3 0.00053 20.0 0.0 3.8 4 0 0 4 4 4 3 LysM domain Glyoxalase PF00903.25 KEZ42478.1 - 0.058 13.6 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank_2 PF12796.7 KEZ42479.1 - 8e-127 414.1 79.1 2.6e-12 47.2 0.2 13.5 4 4 12 18 18 18 18 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ42479.1 - 6.7e-99 323.1 36.4 4.4e-08 33.5 0.1 22.1 10 6 13 23 23 23 21 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ42479.1 - 8.2e-68 216.3 48.2 0.0031 17.9 0.0 28.9 31 0 0 31 31 31 15 Ankyrin repeat Ank PF00023.30 KEZ42479.1 - 2.1e-61 201.9 73.1 0.0021 18.4 0.0 27.5 27 2 1 28 28 28 15 Ankyrin repeat Ank_5 PF13857.6 KEZ42479.1 - 2.6e-53 177.4 43.3 4.9e-07 29.9 0.0 20.2 11 4 13 24 24 24 14 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ42479.1 - 6.7e-07 29.4 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ42479.1 - 0.041 14.3 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Shigella_OspC PF06128.11 KEZ42479.1 - 0.38 10.4 1.4 35 4.0 0.1 3.9 2 1 2 4 4 4 0 Shigella flexneri OspC protein DUF1843 PF08898.10 KEZ42479.1 - 0.98 10.0 14.6 52 4.5 0.0 7.3 8 0 0 8 8 8 0 Domain of unknown function (DUF1843) FAD_binding_3 PF01494.19 KEZ42480.1 - 6.1e-26 91.5 0.0 8.1e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 KEZ42482.1 - 8.1e-40 136.4 0.0 1.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ42482.1 - 1.1e-33 116.8 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ42482.1 - 0.0029 17.5 0.8 0.073 13.0 0.2 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KEZ42482.1 - 0.14 11.6 0.1 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PAP2 PF01569.21 KEZ42483.1 - 3.8e-20 72.0 12.1 2.3e-19 69.5 9.4 2.7 2 1 0 2 2 2 1 PAP2 superfamily Fungal_trans PF04082.18 KEZ42484.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.25 KEZ42485.1 - 2.6e-41 141.3 0.0 3.7e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ42485.1 - 5.4e-26 91.6 0.0 6.9e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ42485.1 - 3.4e-11 43.4 0.1 4.9e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ42485.1 - 1e-08 34.9 0.3 2.1e-08 34.0 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KEZ42485.1 - 0.00067 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KEZ42485.1 - 0.0015 18.4 0.6 0.0029 17.5 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEZ42485.1 - 0.0086 15.5 1.1 0.022 14.2 1.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEZ42485.1 - 0.0094 15.1 0.2 0.025 13.7 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KEZ42485.1 - 0.045 12.9 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LOR PF04525.12 KEZ42486.1 - 4.3e-24 85.1 0.1 5.3e-24 84.8 0.1 1.0 1 0 0 1 1 1 1 LURP-one-related Vps16_N PF04841.13 KEZ42486.1 - 0.069 11.9 0.1 0.09 11.5 0.1 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region Glyco_hydro_61 PF03443.14 KEZ42487.1 - 3.8e-57 193.5 0.0 4.9e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RrnaAD PF00398.20 KEZ42488.1 - 2.4e-63 213.7 0.0 3.1e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KEZ42488.1 - 1.1e-05 26.0 0.0 2.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42488.1 - 0.0002 22.0 0.0 0.00066 20.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KEZ42488.1 - 0.0031 17.3 0.0 0.0083 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KEZ42488.1 - 0.0067 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEZ42488.1 - 0.0089 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF2373 PF10180.9 KEZ42488.1 - 0.014 15.2 0.4 0.52 10.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Methyltransf_12 PF08242.12 KEZ42488.1 - 0.028 15.2 0.0 0.057 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEZ42488.1 - 0.042 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 KEZ42488.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FPN1 PF06963.12 KEZ42489.1 - 2e-114 382.6 12.1 2.4e-114 382.3 12.1 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) TOM6p PF15184.6 KEZ42489.1 - 1.2 8.9 3.5 3.8 7.3 0.4 3.2 4 0 0 4 4 4 0 Mitochondrial import receptor subunit TOM6 homolog Pkinase PF00069.25 KEZ42490.1 - 1e-14 54.6 0.0 2.7e-13 49.9 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42490.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KEZ42490.1 - 0.031 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KEZ42490.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KEZ42490.1 - 0.041 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEZ42490.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_6 PF12697.7 KEZ42491.1 - 2.7e-06 28.1 0.6 5.8e-06 27.1 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Kri1 PF05178.12 KEZ42491.1 - 0.027 15.0 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 KRI1-like family Abhydrolase_1 PF00561.20 KEZ42491.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KEZ42492.1 - 5.2e-37 127.6 14.2 6.6e-37 127.2 14.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 KEZ42492.1 - 0.0048 16.6 2.9 0.25 11.0 0.0 3.0 3 2 0 3 3 3 2 Cation transporting ATPase, C-terminus FMO-like PF00743.19 KEZ42493.1 - 2.7e-28 98.7 0.0 2.4e-15 55.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ42493.1 - 8.3e-12 45.0 0.0 2.7e-08 33.4 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ42493.1 - 4.7e-09 35.9 0.0 1.4e-07 31.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ42493.1 - 7.3e-09 35.2 1.0 7.2e-06 25.4 0.0 3.4 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEZ42493.1 - 0.00012 22.2 0.4 0.00048 20.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEZ42493.1 - 0.00021 21.3 0.3 0.0025 17.8 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KEZ42493.1 - 0.0028 17.3 0.6 0.32 10.5 0.4 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase UPF0149 PF03695.13 KEZ42493.1 - 0.022 15.0 0.2 0.032 14.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Thi4 PF01946.17 KEZ42493.1 - 0.039 13.2 0.1 0.095 11.9 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.20 KEZ42493.1 - 0.086 12.9 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 KEZ42493.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus HET PF06985.11 KEZ42494.1 - 1.1e-13 51.7 0.0 3.2e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4448 PF14610.6 KEZ42495.1 - 1.6e-30 106.3 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 KEZ42495.1 - 4.4e-05 22.8 2.9 7.7e-05 22.0 2.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_hexon PF01065.19 KEZ42495.1 - 0.094 11.5 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Insulin_TMD PF17870.1 KEZ42495.1 - 0.32 11.1 1.4 0.62 10.2 1.4 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment AAA PF00004.29 KEZ42496.1 - 1.2e-16 61.4 0.0 2.2e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ42496.1 - 0.0014 18.9 0.1 0.0071 16.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEZ42496.1 - 0.0036 17.3 0.0 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ42496.1 - 0.0036 17.7 0.2 0.012 16.0 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KEZ42496.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ42496.1 - 0.047 14.2 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ42496.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KEZ42496.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KEZ42496.1 - 0.23 11.2 0.3 0.58 9.9 0.2 1.6 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.6 KEZ42497.1 - 3.2e-15 56.2 7.4 3e-05 24.2 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ42497.1 - 1.1e-07 31.4 7.9 0.054 13.6 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ42497.1 - 2.7e-07 30.2 7.3 0.012 15.5 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ42497.1 - 7.2e-07 28.8 0.5 0.012 15.4 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ42497.1 - 1.5e-05 25.1 0.1 0.37 11.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ42497.1 - 0.00012 22.0 1.7 0.3 11.4 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ42497.1 - 0.00014 22.5 3.9 0.011 16.4 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank_4 PF13637.6 KEZ42497.1 - 0.00048 20.6 0.0 0.002 18.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_7 PF13176.6 KEZ42497.1 - 0.00065 19.5 5.8 0.0041 17.0 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ42497.1 - 0.0066 16.6 2.9 0.98 9.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank_5 PF13857.6 KEZ42497.1 - 0.013 15.8 0.0 0.041 14.2 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ42497.1 - 0.017 15.7 0.0 0.049 14.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ42497.1 - 0.02 15.3 0.1 5.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat HET PF06985.11 KEZ42497.1 - 0.031 14.6 0.2 0.089 13.1 0.2 1.8 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 KEZ42497.1 - 0.033 14.7 0.0 8.3 7.3 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat TPR_19 PF14559.6 KEZ42497.1 - 0.11 13.0 1.8 3.3 8.3 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ42497.1 - 0.12 13.3 11.8 31 5.7 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ42497.1 - 0.76 10.6 4.8 2.3e+02 2.8 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Glyco_hydro_65C PF03633.15 KEZ42498.1 - 0.0014 18.5 1.8 0.0014 18.5 1.8 4.4 2 1 3 5 5 5 3 Glycosyl hydrolase family 65, C-terminal domain DUF3060 PF11259.8 KEZ42498.1 - 0.027 14.1 19.7 0.24 11.1 1.7 4.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3060) Cellulase PF00150.18 KEZ42499.1 - 3.3e-22 79.2 5.1 4.2e-22 78.9 5.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KEZ42499.1 - 5.1e-08 32.4 0.0 1.9e-05 23.9 0.0 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KEZ42499.1 - 0.00067 19.1 4.2 0.0032 16.9 0.0 2.6 2 1 0 2 2 2 1 Beta-galactosidase CDH-cyt PF16010.5 KEZ42501.1 - 6.5e-41 140.0 0.2 1.1e-28 100.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase AltA1 PF16541.5 KEZ42502.1 - 1.5e-09 38.6 1.2 1.1e-06 29.5 0.4 3.2 3 0 0 3 3 3 2 Alternaria alternata allergen 1 DJ-1_PfpI PF01965.24 KEZ42503.1 - 1e-14 54.6 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family CorA PF01544.18 KEZ42504.1 - 2.2e-11 43.6 0.1 4e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RapH_N PF18801.1 KEZ42504.1 - 0.094 12.8 0.4 0.24 11.5 0.4 1.6 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal zf-C2H2 PF00096.26 KEZ42504.1 - 0.16 12.5 0.1 0.36 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Phostensin_N PF13916.6 KEZ42504.1 - 0.41 11.0 2.9 0.56 10.6 1.5 1.9 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Zap1_zf2 PF18217.1 KEZ42504.1 - 7.2 6.7 6.8 25 5.0 6.8 2.0 1 1 0 1 1 1 0 Zap1 zinc finger 2 Tyrosinase PF00264.20 KEZ42505.1 - 2e-31 110.0 0.4 8.5e-31 108.0 0.4 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.21 KEZ42506.1 - 6.5e-10 38.7 0.3 2.2e-09 37.0 0.3 1.9 1 1 0 1 1 1 1 Dioxygenase CorA PF01544.18 KEZ42507.1 - 0.00024 20.5 3.6 0.00056 19.3 3.6 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 KEZ42507.1 - 0.025 14.6 0.8 0.055 13.5 0.8 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III UbiA PF01040.18 KEZ42507.1 - 0.039 13.2 0.9 0.066 12.5 0.9 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF4381 PF14316.6 KEZ42507.1 - 0.075 13.3 1.6 0.2 11.9 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Chromate_transp PF02417.15 KEZ42507.1 - 0.13 12.4 0.3 0.34 11.1 0.3 1.7 1 1 0 1 1 1 0 Chromate transporter Lipoprotein_Ltp PF07553.11 KEZ42510.1 - 0.16 12.3 1.4 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein MFS_1 PF07690.16 KEZ42511.1 - 2.3e-07 30.1 8.4 2.5e-07 30.0 7.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 KEZ42514.1 - 1.9e-15 56.6 0.0 2.2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.22 KEZ42515.1 - 1.1e-65 222.6 0.0 1.7e-65 222.1 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase CTF_NFI PF00859.18 KEZ42515.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region Goodbye PF17109.5 KEZ42516.1 - 4.5e-16 59.4 0.4 4.7e-15 56.1 0.1 3.1 3 0 0 3 3 3 1 fungal STAND N-terminal Goodbye domain AAA_16 PF13191.6 KEZ42516.1 - 7.9e-08 32.9 0.0 3.4e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEZ42516.1 - 0.0008 19.4 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 NACHT domain ZZ PF00569.17 KEZ42516.1 - 0.004 16.9 5.3 0.0091 15.8 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type AAA_19 PF13245.6 KEZ42516.1 - 0.037 14.4 0.0 0.28 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 KEZ42516.1 - 0.11 11.9 1.2 0.42 10.0 1.2 1.9 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PLAC8 PF04749.17 KEZ42517.1 - 8e-23 81.3 10.3 1e-22 81.0 10.3 1.1 1 0 0 1 1 1 1 PLAC8 family PV-1 PF06637.11 KEZ42517.1 - 0.083 11.7 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Gram_pos_anchor PF00746.21 KEZ42518.1 - 1.7 8.6 3.7 0.51 10.3 0.4 2.0 2 1 0 2 2 2 0 LPXTG cell wall anchor motif AIRC PF00731.20 KEZ42519.1 - 2.3e-61 205.7 1.7 6e-61 204.4 1.0 2.1 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KEZ42519.1 - 1.4e-51 174.5 0.0 2.6e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KEZ42519.1 - 2.2e-16 59.3 0.1 1.5e-15 56.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KEZ42519.1 - 3.3e-08 33.3 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 KEZ42519.1 - 2.4e-07 30.5 0.9 3.4e-07 30.0 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain XdhC_C PF13478.6 KEZ42519.1 - 0.0043 17.5 0.4 4 8.0 0.0 3.1 4 0 0 4 4 4 2 XdhC Rossmann domain 3HCDH_N PF02737.18 KEZ42519.1 - 0.042 13.7 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-grasp_4 PF13535.6 KEZ42519.1 - 0.064 12.8 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain PrpR_N PF06506.11 KEZ42519.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Propionate catabolism activator FA_hydroxylase PF04116.13 KEZ42520.1 - 4.7e-24 85.2 14.5 4.7e-24 85.2 14.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily YL1 PF05764.13 KEZ42522.1 - 1.1e-74 251.6 30.2 1.1e-74 251.6 30.2 3.6 4 1 0 4 4 4 2 YL1 nuclear protein YL1_C PF08265.11 KEZ42522.1 - 1.3e-14 53.7 2.9 2.5e-14 52.7 0.7 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 KEZ42522.1 - 0.47 10.4 0.0 0.47 10.4 0.0 2.2 3 0 0 3 3 3 0 HIT zinc finger SNF2_N PF00176.23 KEZ42523.1 - 0.0064 15.3 0.0 0.0096 14.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VPS9 PF02204.18 KEZ42524.1 - 5.1e-25 87.7 0.0 1.1e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KEZ42524.1 - 0.02 15.2 0.0 0.091 13.1 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) CH PF00307.31 KEZ42525.1 - 3.4e-46 155.9 0.1 2.2e-22 79.3 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KEZ42525.1 - 5.2e-22 77.7 6.0 7.4e-22 77.2 0.1 3.6 4 0 0 4 4 4 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KEZ42525.1 - 1.2e-11 44.3 0.2 2.7e-06 27.1 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KEZ42525.1 - 0.00049 19.8 1.2 0.0032 17.3 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 KEZ42525.1 - 0.0017 18.7 2.7 0.01 16.3 2.7 2.5 1 0 0 1 1 1 1 EF-hand domain pair Spectrin PF00435.21 KEZ42525.1 - 0.0088 16.5 11.2 0.098 13.1 3.7 2.8 3 0 0 3 3 3 2 Spectrin repeat EF-hand_8 PF13833.6 KEZ42525.1 - 0.02 14.7 0.8 0.39 10.6 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 KEZ42525.1 - 0.027 14.0 0.3 0.79 9.4 0.0 2.9 2 0 0 2 2 2 0 EF hand FAD-oxidase_C PF02913.19 KEZ42526.1 - 1.7e-64 217.9 0.0 2.3e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ42526.1 - 1.2e-36 125.5 0.6 3.2e-36 124.1 0.6 1.8 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 KEZ42527.1 - 1.6e-07 31.3 12.1 3.1e-07 30.4 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KEZ42528.1 - 1.4e-55 187.7 0.1 2.1e-55 187.2 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEZ42528.1 - 2e-11 43.4 0.1 3.6e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KEZ42528.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.12 KEZ42529.1 - 7e-13 48.9 17.0 1.5e-12 47.8 17.0 1.5 1 1 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 KEZ42529.1 - 0.25 11.2 10.2 4.5 7.2 0.5 3.4 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit zinc_ribbon_10 PF10058.9 KEZ42529.1 - 6.5 6.6 10.9 1.4 8.7 4.1 2.3 1 1 2 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 KEZ42529.1 - 8.1 6.5 12.8 43 4.2 12.8 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KEZ42529.1 - 8.2 6.6 16.6 0.35 11.0 6.6 2.6 3 0 0 3 3 3 0 Zinc ribbon domain C1_4 PF07975.12 KEZ42529.1 - 10 6.5 14.9 8 6.8 0.3 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain TrkH PF02386.16 KEZ42530.1 - 2.1e-131 438.8 11.3 3e-130 435.0 5.3 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L19 PF01245.20 KEZ42531.1 - 1.7e-11 44.1 0.2 3.7e-11 42.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L19 PALP PF00291.25 KEZ42533.1 - 4.8e-66 223.2 0.5 5.8e-66 222.9 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.25 KEZ42534.1 - 3.3e-07 30.1 3.5 3.3e-07 30.1 3.5 5.5 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ42534.1 - 1.4e-06 28.2 4.3 1.4e-06 28.2 4.3 5.0 5 0 0 5 5 5 1 RING-type zinc-finger zf-RING_6 PF14835.6 KEZ42534.1 - 1.6e-06 27.9 0.5 1.6e-06 27.9 0.5 3.4 3 1 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 KEZ42534.1 - 1.9e-06 27.6 3.4 1.9e-06 27.6 3.4 5.4 6 0 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEZ42534.1 - 2e-05 24.8 4.5 2e-05 24.8 4.5 5.0 4 2 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KEZ42534.1 - 3.8e-05 23.5 2.8 3.8e-05 23.5 2.8 5.7 5 1 0 5 5 5 1 zinc-RING finger domain SH3_9 PF14604.6 KEZ42534.1 - 5e-05 23.1 0.2 5e-05 23.1 0.2 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KEZ42534.1 - 0.00016 21.2 0.0 0.00039 20.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain zf-C3HC4_4 PF15227.6 KEZ42534.1 - 0.004 17.3 6.5 0.004 17.3 6.5 4.7 6 1 0 6 6 6 1 zinc finger of C3HC4-type, RING SH3_2 PF07653.17 KEZ42534.1 - 0.0094 15.6 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain ECH_1 PF00378.20 KEZ42535.1 - 5.2e-76 255.3 0.0 6e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ42535.1 - 1.2e-36 126.9 0.2 1.2e-32 113.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 KEZ42536.1 - 6.7e-60 201.7 1.6 8.1e-60 201.4 1.6 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.13 KEZ42537.1 - 3e-87 293.4 0.0 3.4e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Paf1 HeLo PF14479.6 KEZ42538.1 - 3.8e-48 164.1 0.0 7e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation TPR_1 PF00515.28 KEZ42538.1 - 7.7e-10 38.2 9.3 0.00077 19.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ42538.1 - 2.2e-09 36.7 10.6 8.3e-05 22.4 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ42538.1 - 5e-05 22.9 3.5 0.062 13.0 0.1 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 KEZ42538.1 - 0.0004 20.4 8.9 0.076 13.3 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ42538.1 - 0.0031 18.0 3.3 0.012 16.1 1.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ42538.1 - 0.0033 18.1 4.0 0.019 15.8 0.1 3.8 3 1 2 5 5 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ42538.1 - 0.0094 16.3 0.5 1.3 9.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ42538.1 - 0.019 15.1 0.3 0.061 13.5 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ42538.1 - 0.024 14.9 4.7 2.3 8.6 2.3 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ42538.1 - 0.038 14.6 5.6 2.6 8.8 3.5 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ42538.1 - 0.066 13.3 0.2 17 5.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ42538.1 - 3.3 8.6 6.4 1.9 9.3 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S8 PF00410.19 KEZ42539.1 - 1.1e-21 77.0 0.1 1.7e-21 76.5 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.26 KEZ42540.1 - 1.7e-28 98.2 0.6 2.3e-28 97.7 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KEZ42540.1 - 0.089 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Rotamase_3 PF13616.6 KEZ42541.1 - 6.7e-17 62.1 0.3 1.5e-16 61.0 0.2 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KEZ42541.1 - 4.5e-14 53.2 1.4 5.3e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KEZ42541.1 - 0.00035 21.4 7.0 0.016 16.1 7.0 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain SAD_SRA PF02182.17 KEZ42542.1 - 0.0012 18.5 0.1 0.0051 16.5 0.0 1.9 1 1 1 2 2 2 1 SAD/SRA domain TruD PF01142.18 KEZ42543.1 - 9.6e-62 209.1 0.0 7.5e-58 196.3 0.0 3.4 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.25 KEZ42544.1 - 5e-62 209.6 0.0 6.1e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42544.1 - 3.8e-34 118.1 0.0 5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ42544.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEZ42544.1 - 0.00067 18.6 0.0 0.00095 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KEZ42544.1 - 0.14 11.8 0.0 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KEZ42544.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KEZ42544.1 - 0.22 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ42545.1 - 1.8e-15 57.6 0.0 4.6e-15 56.2 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KEZ42545.1 - 2e-05 23.6 0.0 2.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KEZ42545.1 - 0.032 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 KEZ42545.1 - 0.034 13.7 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PTPLA PF04387.14 KEZ42546.1 - 8e-58 194.8 9.3 1.2e-57 194.2 9.3 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF676 PF05057.14 KEZ42547.1 - 0.00018 21.1 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KEZ42547.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEZ42547.1 - 0.0029 18.2 2.6 0.0047 17.6 2.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ42547.1 - 0.035 13.4 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KEZ42547.1 - 0.095 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RIX1 PF08167.12 KEZ42548.1 - 7.9e-47 159.4 5.4 7.9e-47 159.4 5.4 2.6 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 KEZ42549.1 - 5.1e-09 36.2 7.6 0.033 15.0 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ42549.1 - 1.8e-05 24.5 0.4 0.06 13.6 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ42549.1 - 9.1e-05 22.3 18.1 0.045 13.9 0.2 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ42549.1 - 0.00021 21.7 3.0 0.028 14.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ42549.1 - 0.001 18.8 3.6 0.68 9.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ42549.1 - 0.0069 16.3 0.9 15 5.9 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ42549.1 - 0.014 15.7 6.2 0.27 11.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ42549.1 - 0.046 14.4 14.8 6.1 7.6 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ42549.1 - 0.33 11.7 1.6 3.1 8.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_PK PF05891.12 KEZ42550.1 - 6.1e-59 199.2 0.0 6.9e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KEZ42550.1 - 0.00037 20.4 0.0 0.0005 19.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42550.1 - 0.0078 16.9 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42550.1 - 0.043 14.6 0.0 0.13 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain SGL PF08450.12 KEZ42551.1 - 4.3e-67 226.3 0.0 5.4e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KEZ42551.1 - 0.047 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Arylesterase PF01731.20 KEZ42551.1 - 0.056 13.6 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Arylesterase PD40 PF07676.12 KEZ42551.1 - 0.075 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Aldedh PF00171.22 KEZ42552.1 - 8.5e-171 568.5 0.1 1e-170 568.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ42552.1 - 0.11 11.9 0.1 1.9 7.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1487) SseC PF04888.12 KEZ42553.1 - 0.026 14.1 0.8 0.036 13.7 0.8 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family GAGA_bind PF06217.12 KEZ42555.1 - 3.8 7.7 18.0 6.4 7.0 18.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Borrelia_P83 PF05262.11 KEZ42555.1 - 4.2 5.7 31.5 5.1 5.5 31.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.15 KEZ42555.1 - 7.8 5.2 24.0 11 4.7 24.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 KEZ42555.1 - 8.2 5.7 12.6 13 5.0 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M18 PF02127.15 KEZ42556.1 - 2.9e-174 579.9 0.0 3.5e-174 579.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KEZ42556.1 - 1.3e-06 27.7 0.0 0.00021 20.4 0.0 2.5 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase PDZ_1 PF12812.7 KEZ42556.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 PDZ-like domain Med15_fungi PF05397.12 KEZ42557.1 - 0.00031 21.0 0.0 0.00031 21.0 0.0 5.6 7 0 0 7 7 7 1 Mediator complex subunit 15 KIX_2 PF16987.5 KEZ42557.1 - 0.002 18.1 0.1 0.002 18.1 0.1 3.2 4 0 0 4 4 4 1 KIX domain UBD PF16455.5 KEZ42557.1 - 0.054 13.7 1.0 0.18 12.1 1.0 1.8 1 0 0 1 1 1 0 Ubiquitin-binding domain Whi5 PF08528.11 KEZ42558.1 - 5.8e-09 35.4 0.1 1.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Phage_HK97_TLTM PF06120.11 KEZ42559.1 - 0.0038 16.5 2.0 0.021 14.0 0.5 2.2 1 1 1 2 2 2 1 Tail length tape measure protein DUF3972 PF13118.6 KEZ42559.1 - 0.049 14.1 0.8 0.099 13.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) DHR10 PF18595.1 KEZ42559.1 - 0.051 13.6 8.5 0.052 13.6 4.8 2.6 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DUF4200 PF13863.6 KEZ42559.1 - 0.82 10.1 7.2 6.2 7.3 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HR1 PF02185.16 KEZ42559.1 - 1.9 8.7 6.3 48 4.2 4.2 3.3 1 1 2 3 3 3 0 Hr1 repeat RTA1 PF04479.13 KEZ42560.1 - 2.6e-63 213.4 10.0 2.6e-63 213.4 10.0 1.4 2 0 0 2 2 2 1 RTA1 like protein UL42 PF17638.2 KEZ42560.1 - 0.00054 19.9 0.9 0.00054 19.9 0.9 1.9 2 0 0 2 2 2 1 HCMV UL42 Xpo1 PF08389.12 KEZ42563.1 - 9.2e-36 123.1 3.1 8.2e-35 120.1 0.1 3.7 3 1 0 3 3 3 1 Exportin 1-like protein HsbA PF12296.8 KEZ42563.1 - 1.6e-09 38.2 12.2 1.6e-09 38.2 12.2 2.9 3 0 0 3 3 3 1 Hydrophobic surface binding protein A V-ATPase_H_N PF03224.14 KEZ42563.1 - 0.0041 16.4 0.4 0.014 14.7 0.4 2.0 1 0 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.22 KEZ42563.1 - 0.014 15.6 0.0 8.1 7.0 0.0 3.8 2 0 0 2 2 2 0 HEAT repeat CorA PF01544.18 KEZ42564.1 - 0.00026 20.4 0.1 0.00048 19.6 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein LMBR1 PF04791.16 KEZ42565.1 - 2.5e-112 376.4 10.0 2.8e-112 376.2 10.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Hat1_N PF10394.9 KEZ42566.1 - 9.1e-41 139.8 0.0 1.4e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KEZ42566.1 - 0.0049 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ42566.1 - 0.0064 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CTK3 PF12243.8 KEZ42567.1 - 6.7e-47 158.5 0.6 1.1e-46 157.9 0.6 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KEZ42567.1 - 2.9e-17 62.6 14.0 2.9e-17 62.6 14.0 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus ImcF-related_N PF14331.6 KEZ42567.1 - 0.075 12.4 0.9 0.17 11.2 0.3 1.8 2 0 0 2 2 2 0 ImcF-related N-terminal domain Ribosomal_L12 PF00542.19 KEZ42568.1 - 1.6e-21 76.4 4.3 2.9e-20 72.4 2.8 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KEZ42568.1 - 3.3e-10 39.5 12.8 3.3e-10 39.5 12.8 3.6 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain AAA_5 PF07728.14 KEZ42569.1 - 7.3e-126 414.7 0.1 1.4e-21 76.9 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KEZ42569.1 - 3e-54 181.7 8.7 7.5e-24 84.0 0.0 6.3 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KEZ42569.1 - 3.4e-33 113.9 0.7 2.1e-30 104.9 0.0 4.7 5 0 0 5 5 3 1 Midasin AAA lid domain AAA_16 PF13191.6 KEZ42569.1 - 8.9e-31 107.5 21.1 8.6e-06 26.2 0.4 9.1 7 3 0 7 7 6 6 AAA ATPase domain AAA_3 PF07726.11 KEZ42569.1 - 1.5e-29 102.5 0.0 9.5e-10 38.4 0.0 7.5 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KEZ42569.1 - 1.5e-29 103.1 0.1 0.0002 21.8 0.0 7.7 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 KEZ42569.1 - 1.7e-27 95.9 0.0 7.7e-05 22.8 0.0 8.1 8 0 0 8 8 7 5 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 KEZ42569.1 - 3.6e-27 95.1 2.2 3.3e-05 23.5 0.0 7.0 7 0 0 7 7 7 5 P-loop containing dynein motor region AAA_6 PF12774.7 KEZ42569.1 - 1.1e-22 80.5 0.0 0.023 13.7 0.0 8.9 9 0 0 9 9 8 6 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KEZ42569.1 - 2.1e-21 76.7 1.6 0.016 15.5 0.0 8.1 7 0 0 7 7 6 4 AAA domain AAA_33 PF13671.6 KEZ42569.1 - 7.4e-20 71.6 0.0 0.0096 16.1 0.0 7.4 6 1 0 6 6 6 3 AAA domain Sigma54_activat PF00158.26 KEZ42569.1 - 2.1e-19 69.8 0.0 0.02 14.6 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.6 KEZ42569.1 - 2.2e-19 70.3 0.2 0.0054 17.3 0.0 7.1 6 0 0 6 6 6 4 AAA domain TsaE PF02367.17 KEZ42569.1 - 2.7e-16 59.7 4.7 0.037 14.0 0.1 6.6 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KEZ42569.1 - 4e-16 59.3 0.0 0.0066 16.5 0.0 7.5 7 0 0 7 7 6 2 AAA domain AAA_30 PF13604.6 KEZ42569.1 - 6.4e-16 58.6 0.1 0.027 14.2 0.0 8.0 7 1 0 7 7 7 2 AAA domain ABC_tran PF00005.27 KEZ42569.1 - 6.3e-15 55.9 2.0 0.012 16.1 0.0 7.6 6 0 0 6 6 6 2 ABC transporter T2SSE PF00437.20 KEZ42569.1 - 1e-14 54.2 5.7 0.018 14.1 0.1 6.6 6 0 0 6 6 6 2 Type II/IV secretion system protein RNA_helicase PF00910.22 KEZ42569.1 - 2.9e-14 53.4 1.4 0.34 11.3 0.0 6.7 6 0 0 6 6 6 2 RNA helicase NACHT PF05729.12 KEZ42569.1 - 3.9e-14 52.9 6.5 0.21 11.5 0.0 7.3 7 0 0 7 7 6 3 NACHT domain Sigma54_activ_2 PF14532.6 KEZ42569.1 - 8.9e-14 51.8 0.4 0.0026 17.9 0.0 6.7 6 0 0 6 6 6 2 Sigma-54 interaction domain Rad17 PF03215.15 KEZ42569.1 - 1.7e-13 50.9 1.7 0.05 13.5 0.0 6.6 6 0 0 6 6 6 2 Rad17 P-loop domain Mg_chelatase PF01078.21 KEZ42569.1 - 2.5e-13 49.9 0.9 5.7 6.3 0.0 9.6 10 0 0 10 10 10 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 KEZ42569.1 - 8.5e-13 48.5 5.8 0.16 11.9 0.1 6.4 6 0 0 6 6 6 3 RsgA GTPase RuvB_N PF05496.12 KEZ42569.1 - 1.5e-12 47.6 3.4 0.017 14.8 0.0 6.7 7 0 0 7 7 5 2 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 KEZ42569.1 - 2e-11 43.9 0.3 1.2 8.6 0.0 6.0 5 0 0 5 5 5 4 AAA domain AAA_29 PF13555.6 KEZ42569.1 - 7.1e-11 41.7 0.9 0.56 10.0 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEZ42569.1 - 9.7e-11 41.3 6.7 0.0087 15.4 0.0 7.2 7 0 0 7 7 6 1 Zeta toxin IstB_IS21 PF01695.17 KEZ42569.1 - 1.4e-10 41.2 0.0 0.29 10.8 0.0 6.9 6 1 1 7 7 7 1 IstB-like ATP binding protein AAA_28 PF13521.6 KEZ42569.1 - 2.9e-10 40.6 8.6 0.68 10.2 0.0 7.7 8 0 0 8 8 6 1 AAA domain SRP54 PF00448.22 KEZ42569.1 - 2.5e-09 37.1 2.9 0.47 10.1 0.0 5.7 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain AAA_19 PF13245.6 KEZ42569.1 - 1.7e-08 34.9 3.8 2.4 8.5 0.0 6.2 5 0 0 5 5 5 1 AAA domain CbiA PF01656.23 KEZ42569.1 - 3.8e-08 33.4 0.1 0.06 13.4 0.0 5.3 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain TniB PF05621.11 KEZ42569.1 - 9.4e-08 31.7 0.1 1.1 8.6 0.0 5.8 6 0 0 6 6 6 2 Bacterial TniB protein AAA_24 PF13479.6 KEZ42569.1 - 1.6e-07 31.2 0.0 3.1 7.5 0.0 6.1 6 0 0 6 6 6 0 AAA domain PduV-EutP PF10662.9 KEZ42569.1 - 3.3e-07 30.1 2.9 0.046 13.5 0.0 5.3 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 KEZ42569.1 - 1.3e-06 27.7 2.2 6 5.9 0.0 5.7 6 0 0 6 6 6 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KEZ42569.1 - 1.9e-06 27.8 0.2 0.03 14.1 0.0 5.3 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KEZ42569.1 - 7.4e-06 25.3 1.5 3.1 6.9 0.1 5.4 5 0 0 5 5 5 0 NB-ARC domain NTPase_1 PF03266.15 KEZ42569.1 - 9.1e-06 25.7 9.4 1.9 8.4 0.0 6.1 5 0 0 5 5 5 1 NTPase TIP49 PF06068.13 KEZ42569.1 - 2.2e-05 23.9 0.2 5.9 6.0 0.0 4.9 5 0 0 5 5 5 0 TIP49 P-loop domain AAA_17 PF13207.6 KEZ42569.1 - 3.9e-05 24.1 5.8 2.2 8.7 0.0 6.0 5 0 0 5 5 5 1 AAA domain dNK PF01712.19 KEZ42569.1 - 4.2e-05 23.5 5.4 9.3 6.0 0.0 6.1 6 0 0 6 6 6 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 KEZ42569.1 - 5.4e-05 23.3 3.5 39 4.4 0.0 6.4 6 0 0 6 6 5 0 50S ribosome-binding GTPase ResIII PF04851.15 KEZ42569.1 - 6.6e-05 23.0 0.0 2 8.4 0.0 5.0 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 KEZ42569.1 - 0.00012 22.0 11.8 4.7 6.9 0.1 6.7 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein KTI12 PF08433.10 KEZ42569.1 - 0.0003 20.3 2.5 0.99 8.8 0.0 5.5 6 0 0 6 6 6 1 Chromatin associated protein KTI12 CPT PF07931.12 KEZ42569.1 - 0.00044 20.1 2.2 16 5.3 0.0 6.7 7 1 0 7 7 5 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KEZ42569.1 - 0.00054 19.4 0.2 2.4 7.4 0.0 4.6 5 0 0 5 5 4 1 KaiC Thymidylate_kin PF02223.17 KEZ42569.1 - 0.00062 19.5 3.2 6.7 6.3 0.0 5.9 6 0 0 6 6 5 0 Thymidylate kinase Roc PF08477.13 KEZ42569.1 - 0.00093 19.4 4.0 12 6.2 0.1 5.9 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase VWA PF00092.28 KEZ42569.1 - 0.0011 19.2 0.0 0.004 17.4 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain MCM PF00493.23 KEZ42569.1 - 0.0043 16.2 0.2 15 4.6 0.0 4.9 7 0 0 7 7 6 0 MCM P-loop domain SRPRB PF09439.10 KEZ42569.1 - 0.0047 16.4 1.8 14 5.0 0.0 5.3 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit DEAD PF00270.29 KEZ42569.1 - 0.0058 16.4 0.5 8 6.2 0.0 4.5 5 0 0 5 5 3 0 DEAD/DEAH box helicase AAA_8 PF12780.7 KEZ42569.1 - 0.0078 15.6 1.4 36 3.6 0.0 5.2 6 0 0 6 6 4 0 P-loop containing dynein motor region D4 cobW PF02492.19 KEZ42569.1 - 0.0096 15.5 10.0 18 4.9 0.1 5.8 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 KEZ42569.1 - 0.011 15.5 0.7 10 5.8 0.0 4.2 5 0 0 5 5 4 0 Phosphoribulokinase / Uridine kinase family DAP3 PF10236.9 KEZ42569.1 - 0.012 14.9 6.4 2.8 7.0 0.0 5.1 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 SKI PF01202.22 KEZ42569.1 - 0.012 15.7 1.1 20 5.3 0.0 4.8 4 0 0 4 4 4 0 Shikimate kinase KAP_NTPase PF07693.14 KEZ42569.1 - 0.016 14.4 0.0 13 4.9 0.0 4.8 5 0 0 5 5 4 0 KAP family P-loop domain VWA_2 PF13519.6 KEZ42569.1 - 0.024 15.3 0.5 0.57 10.9 0.0 3.3 3 0 0 3 3 2 0 von Willebrand factor type A domain MeaB PF03308.16 KEZ42569.1 - 0.028 13.4 0.9 8.9 5.2 0.1 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB tRNA_lig_kinase PF08303.11 KEZ42569.1 - 0.032 14.3 2.2 0.52 10.4 0.0 3.3 3 0 0 3 3 2 0 tRNA ligase kinase domain APS_kinase PF01583.20 KEZ42569.1 - 0.055 13.4 0.9 29 4.5 0.0 4.4 5 0 0 5 5 3 0 Adenylylsulphate kinase PhoH PF02562.16 KEZ42569.1 - 0.1 12.0 1.1 14 5.1 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein Septin PF00735.18 KEZ42569.1 - 0.13 11.6 0.8 39 3.4 0.0 4.0 5 0 0 5 5 4 0 Septin Parvo_NS1 PF01057.17 KEZ42569.1 - 0.19 10.8 0.0 23 4.0 0.0 3.0 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 KEZ42569.1 - 0.3 10.8 6.2 59 3.3 0.2 5.3 5 0 0 5 5 5 0 Cytidylate kinase Ploopntkinase3 PF18751.1 KEZ42569.1 - 1 9.2 4.1 34 4.3 0.0 4.4 6 0 0 6 6 4 0 P-loop Nucleotide Kinase3 bZIP_1 PF00170.21 KEZ42570.1 - 3.5e-06 27.0 7.1 3.5e-06 27.0 7.1 1.7 2 0 0 2 2 2 1 bZIP transcription factor Nop53 PF07767.11 KEZ42570.1 - 0.06 12.7 11.9 0.055 12.8 9.2 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF5595 PF18077.1 KEZ42570.1 - 0.34 11.0 2.0 0.29 11.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) bZIP_2 PF07716.15 KEZ42570.1 - 0.83 9.8 11.1 0.37 10.9 7.8 2.1 2 1 0 2 2 2 0 Basic region leucine zipper Vir_act_alpha_C PF10400.9 KEZ42570.1 - 0.87 10.3 4.8 0.74 10.5 3.1 1.8 2 0 0 2 2 2 0 Virulence activator alpha C-term Hypoth_Ymh PF09509.10 KEZ42571.1 - 0.012 15.5 0.1 0.032 14.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) GRP PF07172.11 KEZ42572.1 - 0.016 15.9 14.6 0.016 15.9 14.6 1.8 2 0 0 2 2 2 0 Glycine rich protein family PBP1_TM PF14812.6 KEZ42573.1 - 0.033 14.6 4.0 0.059 13.8 4.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gram_pos_anchor PF00746.21 KEZ42573.1 - 0.11 12.4 0.9 0.31 11.0 0.9 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Cation_ATPase_C PF00689.21 KEZ42574.1 - 2.6e-46 157.6 11.4 2.6e-46 157.6 11.4 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEZ42574.1 - 9e-34 116.6 0.1 9e-34 116.6 0.1 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ42574.1 - 1.4e-20 74.5 0.1 4.6e-19 69.5 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ42574.1 - 1.7e-20 72.8 0.0 3.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEZ42574.1 - 1.4e-06 27.9 0.1 4.5e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ42574.1 - 2e-06 27.7 0.2 0.00046 20.0 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ42574.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Med10 PF09748.9 KEZ42575.1 - 2.8e-48 162.9 0.0 3.2e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 KEZ42575.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF2294 PF10057.9 KEZ42575.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) CAGE1 PF15066.6 KEZ42575.1 - 0.26 9.9 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family TPR_1 PF00515.28 KEZ42576.1 - 2.9e-40 134.5 6.3 4.7e-08 32.5 0.2 8.6 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ42576.1 - 1.7e-39 130.7 6.1 5.4e-06 26.1 0.2 8.6 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ42576.1 - 2.3e-30 104.0 6.8 1.5e-07 31.0 0.3 7.1 5 2 2 7 7 7 5 TPR repeat DnaJ PF00226.31 KEZ42576.1 - 1.5e-27 95.5 6.4 3.3e-27 94.4 4.1 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 KEZ42576.1 - 9.1e-23 80.6 6.5 2.2e-08 34.5 0.0 6.1 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ42576.1 - 2.1e-22 79.5 4.4 9.9e-07 29.3 0.6 7.1 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ42576.1 - 2.3e-20 71.5 14.2 0.00034 21.2 0.2 8.9 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ42576.1 - 1e-19 69.0 4.1 0.001 19.1 0.2 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ42576.1 - 5.4e-17 61.9 7.0 0.0063 16.8 0.1 7.2 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ42576.1 - 5.5e-17 60.8 7.6 0.00081 19.6 0.4 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ42576.1 - 1.4e-12 47.7 2.1 2.8e-05 24.2 0.0 3.9 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEZ42576.1 - 4.8e-12 45.9 6.7 0.00091 19.3 0.2 5.3 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ42576.1 - 7.1e-12 44.5 4.0 0.23 11.6 0.1 7.3 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ42576.1 - 6.9e-09 35.3 2.7 0.0041 16.4 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ42576.1 - 3.8e-08 33.4 11.4 12 6.8 0.1 8.5 9 1 0 9 9 7 0 Tetratricopeptide repeat BTAD PF03704.17 KEZ42576.1 - 1.8e-05 25.2 2.8 5.6 7.4 0.0 4.8 2 2 2 4 4 4 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 KEZ42576.1 - 9.4e-05 22.4 2.9 5.2 7.2 0.0 5.0 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KEZ42576.1 - 0.00039 19.5 0.3 0.0089 15.1 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KEZ42576.1 - 0.0005 19.8 13.6 0.79 9.7 0.5 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Coatomer_E PF04733.14 KEZ42576.1 - 0.00089 18.8 0.1 0.47 9.8 0.0 2.5 2 0 0 2 2 2 2 Coatomer epsilon subunit MIT PF04212.18 KEZ42576.1 - 0.0011 18.9 6.9 0.46 10.6 0.1 4.2 2 2 2 4 4 4 2 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 KEZ42576.1 - 0.024 15.1 0.4 44 4.5 0.0 3.5 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation RRM_3 PF08777.11 KEZ42576.1 - 0.049 13.7 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 RNA binding motif MscS_porin PF12795.7 KEZ42576.1 - 0.11 12.0 0.2 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain NST1 PF13945.6 KEZ42576.1 - 3.4 7.7 8.3 0.15 12.2 2.2 1.8 2 0 0 2 2 1 0 Salt tolerance down-regulator Cutinase PF01083.22 KEZ42577.1 - 2.1e-52 177.7 6.2 2.6e-52 177.3 6.2 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.18 KEZ42577.1 - 1.1e-12 47.6 21.3 1.1e-12 47.6 21.3 4.2 3 1 0 3 3 3 1 Fungal cellulose binding domain PE-PPE PF08237.11 KEZ42577.1 - 5.1e-05 22.9 0.1 7.8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 KEZ42577.1 - 0.00061 19.5 0.1 0.00064 19.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Toxin_7 PF05980.12 KEZ42577.1 - 3.5 8.0 20.4 0.64 10.3 9.4 2.9 2 1 1 3 3 3 0 Toxin 7 EF-hand_6 PF13405.6 KEZ42578.1 - 8.5e-13 47.1 0.3 7.7e-06 25.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KEZ42578.1 - 1.9e-11 42.6 0.7 4.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KEZ42578.1 - 9.3e-08 32.4 0.0 0.0055 17.1 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KEZ42578.1 - 1.2e-07 30.8 2.8 0.00022 20.6 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KEZ42578.1 - 4.7e-05 23.1 0.1 0.37 10.7 0.1 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 KEZ42578.1 - 0.00034 20.9 0.0 0.78 10.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Afi1 PF07792.12 KEZ42580.1 - 9.4e-50 168.5 0.7 1.5e-49 167.9 0.7 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KEZ42580.1 - 1.9e-36 124.5 0.0 3.4e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KEZ42580.1 - 8.9e-08 31.2 0.0 0.017 13.8 0.0 4.0 3 1 1 4 4 4 2 Transport protein Avl9 Nop53 PF07767.11 KEZ42580.1 - 0.027 13.9 7.9 0.056 12.8 7.9 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) KIX_2 PF16987.5 KEZ42580.1 - 0.08 13.0 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 KIX domain DUF2347 PF09804.9 KEZ42580.1 - 0.092 12.3 0.0 0.51 9.9 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF1168 PF06658.12 KEZ42580.1 - 0.11 12.3 10.1 0.22 11.3 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CSRNP_N PF16019.5 KEZ42580.1 - 0.14 12.0 1.3 0.24 11.3 1.3 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Astro_capsid_p PF12226.8 KEZ42580.1 - 0.14 11.3 4.6 0.23 10.6 4.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Esterase PF00756.20 KEZ42581.1 - 1.9e-45 155.5 0.0 2.3e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KEZ42581.1 - 0.00033 20.2 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 KEZ42581.1 - 0.00061 19.3 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KEZ42581.1 - 0.0097 15.2 0.0 0.02 14.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KEZ42581.1 - 0.038 12.9 0.0 0.07 12.0 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 KEZ42581.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Tyrosinase PF00264.20 KEZ42582.1 - 1.5e-45 156.2 0.0 2.2e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Myb_DNA-bind_5 PF13873.6 KEZ42582.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain RNA_pol_Rpb6 PF01192.22 KEZ42583.1 - 2.7e-17 62.4 0.2 5.5e-17 61.4 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 KEZ42583.1 - 0.052 13.5 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit zf-C2H2 PF00096.26 KEZ42584.1 - 4.4e-35 118.2 54.6 6e-05 23.3 0.6 10.8 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ42584.1 - 1.2e-20 72.3 62.7 0.00051 20.7 0.8 11.3 12 0 0 12 12 11 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEZ42584.1 - 1.8e-15 56.6 50.5 0.0012 19.2 0.0 10.3 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KEZ42584.1 - 1.4e-10 41.1 25.4 0.22 11.9 0.0 10.1 10 0 0 10 10 10 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KEZ42584.1 - 1.2e-09 38.6 34.8 0.051 14.2 0.3 8.8 6 2 3 9 9 8 5 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KEZ42584.1 - 5.4e-06 26.6 16.5 0.035 14.4 3.4 5.2 3 1 2 5 5 5 3 C2H2-type zinc ribbon zf-met PF12874.7 KEZ42584.1 - 7.6e-06 26.1 26.2 11 6.5 0.0 9.7 10 0 0 10 10 10 1 Zinc-finger of C2H2 type zf_Hakai PF18408.1 KEZ42584.1 - 4.5e-05 23.1 20.8 0.0089 15.7 0.0 7.8 8 0 0 8 8 8 2 C2H2 Hakai zinc finger domain zf-C2H2_aberr PF17017.5 KEZ42584.1 - 6.2e-05 23.2 16.2 0.11 12.7 0.1 6.1 5 2 2 7 7 7 2 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KEZ42584.1 - 0.00017 21.4 6.6 0.0065 16.3 0.2 4.7 4 0 0 4 4 4 1 zinc-finger of a C2HC-type DUF4187 PF13821.6 KEZ42584.1 - 0.00067 19.4 3.0 0.0047 16.7 0.2 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4187) zf_ZIC PF18366.1 KEZ42584.1 - 0.085 13.0 7.0 41 4.4 0.0 6.3 6 1 1 7 7 7 0 Zic proteins zinc finger domain zf-C2H2_11 PF16622.5 KEZ42584.1 - 0.32 10.8 25.0 2.3 8.0 0.0 6.8 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2HE PF16278.5 KEZ42584.1 - 5.8 7.4 15.7 16 6.0 1.5 4.4 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HNH_5 PF14279.6 KEZ42584.1 - 7.5 6.5 10.8 1.3 8.9 1.2 3.9 4 0 0 4 4 4 0 HNH endonuclease Zip PF02535.22 KEZ42585.1 - 4.3e-29 101.8 5.1 1.1e-28 100.5 5.1 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DctQ PF04290.12 KEZ42585.1 - 0.016 15.1 2.8 0.016 15.1 2.8 2.2 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component WD40 PF00400.32 KEZ42586.1 - 5.7e-31 106.1 26.6 1.6e-05 25.6 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42586.1 - 1.3e-12 47.8 0.2 0.5 10.7 0.1 5.9 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KEZ42586.1 - 0.051 13.5 0.0 3.4 7.5 0.0 2.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KEZ42586.1 - 0.2 9.9 0.0 0.34 9.2 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz MBOAT PF03062.19 KEZ42587.1 - 5.5e-20 72.0 19.1 8e-20 71.5 19.1 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KEZ42587.1 - 0.0051 17.1 2.4 0.017 15.4 2.4 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Tmemb_170 PF10190.9 KEZ42588.1 - 3.8e-27 94.7 14.4 4.3e-27 94.6 14.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Hexapep PF00132.24 KEZ42589.1 - 9.3e-11 41.0 5.4 1.4e-08 34.1 2.3 3.0 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 KEZ42589.1 - 1e-10 41.7 0.1 1.6e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 KEZ42589.1 - 1.7e-10 40.4 5.8 2.8e-07 30.2 1.9 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase LysM PF01476.20 KEZ42591.1 - 1e-07 31.9 0.0 0.00045 20.2 0.0 3.3 3 0 0 3 3 3 2 LysM domain Ubiq_cyt_C_chap PF03981.12 KEZ42592.1 - 8.9e-32 110.1 1.0 2.3e-31 108.8 0.5 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone OPT PF03169.15 KEZ42593.1 - 6.6e-173 576.6 47.5 8.1e-173 576.4 47.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ketoacyl-synt PF00109.26 KEZ42593.1 - 4.8e-56 190.2 2.6 2.9e-55 187.6 0.3 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ42593.1 - 1e-36 125.5 0.6 1.9e-36 124.7 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KEZ42593.1 - 8.7e-05 22.0 1.3 0.00044 19.7 0.3 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ42593.1 - 0.017 14.7 0.7 0.048 13.3 0.1 2.0 2 0 0 2 2 2 0 Thiolase, C-terminal domain AflR PF08493.10 KEZ42594.1 - 0.16 11.4 1.4 14 5.0 0.9 2.4 2 0 0 2 2 2 0 Aflatoxin regulatory protein Dioxygenase_C PF00775.21 KEZ42595.1 - 4.6e-53 179.4 0.0 7.8e-53 178.6 0.0 1.4 2 0 0 2 2 2 1 Dioxygenase Dioxygenase_N PF04444.14 KEZ42595.1 - 7.5e-28 96.2 0.1 1.3e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KEZ42595.1 - 1.1e-07 32.0 0.0 7.8e-06 26.1 0.0 2.9 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.18 KEZ42596.1 - 1.8e-08 33.7 0.2 6.8e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42596.1 - 6.3e-08 32.6 12.7 1.2e-07 31.7 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 KEZ42597.1 - 6e-15 55.1 5.7 4.2e-05 23.8 2.0 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEZ42597.1 - 1.1e-12 47.5 8.2 1.7e-08 34.1 4.2 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KEZ42597.1 - 2.5e-06 27.2 6.9 4.5 8.2 0.1 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.6 KEZ42597.1 - 0.0018 17.8 0.4 0.0067 15.9 0.3 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KEZ42597.1 - 0.0025 17.7 10.3 24 5.3 1.7 5.6 5 0 0 5 5 5 1 Leucine Rich repeat Hom_end PF05204.14 KEZ42597.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease Actin PF00022.19 KEZ42598.1 - 4e-90 302.4 0.0 2e-87 293.5 0.0 2.8 1 1 0 1 1 1 1 Actin Phage_Mu_Gp45 PF06890.12 KEZ42598.1 - 0.12 12.2 0.0 0.56 10.0 0.0 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gp45 protein MreB_Mbl PF06723.13 KEZ42598.1 - 0.19 10.5 0.1 0.44 9.3 0.1 1.9 1 1 0 1 1 1 0 MreB/Mbl protein zf-HC5HC2H_2 PF13832.6 KEZ42599.1 - 1.9e-33 114.9 8.2 1.9e-33 114.9 8.2 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KEZ42599.1 - 2.5e-29 102.7 0.0 7.1e-28 98.0 0.0 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KEZ42599.1 - 1.5e-25 89.2 7.9 1.5e-25 89.2 7.9 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KEZ42599.1 - 3.4e-14 52.1 1.9 3.4e-14 52.1 1.9 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KEZ42599.1 - 6.5e-10 38.7 22.3 5.6e-09 35.8 9.1 2.8 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KEZ42599.1 - 4.9 6.7 15.1 0.017 14.7 1.6 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Metallophos PF00149.28 KEZ42600.1 - 3.9e-40 138.5 0.1 5.1e-40 138.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEZ42600.1 - 3.4e-23 81.8 2.0 4.6e-23 81.4 1.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Rdx PF10262.9 KEZ42601.1 - 1.9e-31 108.1 0.0 2.9e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 KEZ42602.1 - 3.6e-25 87.7 0.0 4.3e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 GGL domain Ribosomal_L11 PF00298.19 KEZ42602.1 - 0.026 15.0 0.0 0.032 14.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain PCI PF01399.27 KEZ42603.1 - 9.9e-09 35.7 0.5 1.3e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 PCI domain AAA_13 PF13166.6 KEZ42604.1 - 3.3e-07 29.4 30.5 0.00026 19.8 10.3 2.1 1 1 1 2 2 2 2 AAA domain Laminin_II PF06009.12 KEZ42604.1 - 6.4e-07 29.5 52.6 0.0073 16.3 8.3 4.8 1 1 3 4 4 4 4 Laminin Domain II Fib_alpha PF08702.10 KEZ42604.1 - 1.8e-06 28.2 26.3 0.0017 18.6 6.2 4.5 1 1 4 5 5 5 3 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 KEZ42604.1 - 5e-06 26.2 2.4 0.13 11.8 0.1 3.5 1 1 2 3 3 3 2 Mechanosensitive ion channel porin domain PspA_IM30 PF04012.12 KEZ42604.1 - 5.6e-05 22.8 30.9 0.0045 16.6 9.5 3.8 1 1 2 3 3 3 3 PspA/IM30 family MIP-T3_C PF17749.1 KEZ42604.1 - 0.00039 20.4 17.7 0.8 9.7 0.5 4.8 1 1 3 4 4 4 3 Microtubule-binding protein MIP-T3 C-terminal region ATG16 PF08614.11 KEZ42604.1 - 0.00092 19.5 32.0 0.012 15.8 9.8 3.3 1 1 3 4 4 3 3 Autophagy protein 16 (ATG16) Laminin_I PF06008.14 KEZ42604.1 - 0.004 16.9 21.2 0.35 10.5 2.5 3.2 1 1 2 3 3 3 3 Laminin Domain I MCPsignal PF00015.21 KEZ42604.1 - 0.0041 17.0 14.5 0.0041 17.0 14.5 5.0 1 1 5 6 6 6 3 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF745 PF05335.13 KEZ42604.1 - 0.0045 16.7 35.9 0.21 11.3 13.9 3.8 1 1 2 3 3 3 1 Protein of unknown function (DUF745) EzrA PF06160.12 KEZ42604.1 - 0.0052 15.0 40.3 0.17 10.0 17.3 3.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA TMPIT PF07851.13 KEZ42604.1 - 0.0091 15.3 15.8 0.03 13.6 1.9 2.9 1 1 2 3 3 3 2 TMPIT-like protein DUF4200 PF13863.6 KEZ42604.1 - 0.016 15.6 11.8 0.041 14.3 2.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SlyX PF04102.12 KEZ42604.1 - 0.017 15.7 21.5 1.9 9.1 1.1 4.6 1 1 3 4 4 4 0 SlyX Vac_Fusion PF02346.16 KEZ42604.1 - 0.04 13.5 6.4 45 3.8 0.1 5.4 1 1 5 6 6 6 0 Chordopoxvirus multifunctional envelope protein A27 DUF1664 PF07889.12 KEZ42604.1 - 0.061 13.4 52.1 0.029 14.4 6.5 4.9 2 1 3 5 5 4 0 Protein of unknown function (DUF1664) Med9 PF07544.13 KEZ42604.1 - 0.064 13.3 12.2 2.2 8.4 0.5 5.1 2 1 3 5 5 4 0 RNA polymerase II transcription mediator complex subunit 9 PilJ PF13675.6 KEZ42604.1 - 0.069 13.2 7.3 6 6.9 2.5 3.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term BST2 PF16716.5 KEZ42604.1 - 0.078 13.6 16.8 1.2 9.7 0.8 4.6 1 1 5 6 6 6 0 Bone marrow stromal antigen 2 HrpB7 PF09486.10 KEZ42604.1 - 0.097 13.1 42.2 0.67 10.3 17.4 4.2 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) WXG100 PF06013.12 KEZ42604.1 - 0.11 12.7 9.9 1.1 9.5 1.7 3.8 1 1 3 4 4 4 0 Proteins of 100 residues with WXG DUF5012 PF16404.5 KEZ42604.1 - 0.19 11.9 9.8 27 4.9 0.2 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF5012) Prominin PF05478.11 KEZ42604.1 - 0.34 8.8 15.0 0.34 8.8 12.8 1.9 1 1 1 2 2 2 0 Prominin Sulfatase_C PF14707.6 KEZ42604.1 - 0.47 11.2 18.3 26 5.6 0.8 4.9 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase Swi5 PF07061.11 KEZ42604.1 - 0.5 10.5 12.6 29 4.8 0.6 4.9 1 1 3 4 4 4 0 Swi5 Tweety PF04906.13 KEZ42604.1 - 0.53 8.9 25.5 1.3 7.6 4.6 3.9 1 1 3 4 4 4 0 Tweety DUF724 PF05266.14 KEZ42604.1 - 0.86 9.4 29.5 0.98 9.2 9.4 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF724) DUF3552 PF12072.8 KEZ42604.1 - 0.88 9.0 44.3 1.2 8.5 10.8 4.2 1 1 4 5 5 5 0 Domain of unknown function (DUF3552) COG5 PF10392.9 KEZ42604.1 - 1.2 9.3 11.1 0.98 9.6 0.7 3.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 XhlA PF10779.9 KEZ42604.1 - 1.3 9.2 31.9 2.9 8.2 1.3 5.6 1 1 3 5 5 5 0 Haemolysin XhlA Spc7 PF08317.11 KEZ42604.1 - 1.4 7.7 51.0 0.03 13.2 14.7 3.7 1 1 3 4 4 4 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 KEZ42604.1 - 1.5 9.3 15.9 28 5.2 0.6 5.0 1 1 3 4 4 4 0 Snapin/Pallidin BORCS7 PF16088.5 KEZ42604.1 - 1.7 8.9 19.0 6.5 7.1 0.7 4.8 1 1 3 4 4 4 0 BLOC-1-related complex sub-unit 7 BORCS8 PF10167.9 KEZ42604.1 - 2 8.4 25.2 9.1 6.3 1.6 5.3 1 1 3 4 4 4 0 BLOC-1-related complex sub-unit 8 Uds1 PF15456.6 KEZ42604.1 - 3.8 7.7 28.3 8 6.6 1.4 5.0 1 1 3 4 4 4 0 Up-regulated During Septation TMP_2 PF06791.13 KEZ42604.1 - 4.1 7.0 4.5 24 4.5 0.7 2.5 1 1 2 3 3 3 0 Prophage tail length tape measure protein BLOC1_2 PF10046.9 KEZ42604.1 - 4.6 7.6 37.6 1.8e+02 2.5 4.6 4.7 1 1 2 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 KEZ42604.1 - 4.8 7.9 32.3 4.6 8.0 6.2 4.1 2 1 2 4 4 3 0 Uncharacterized conserved protein (DUF2203) ISG65-75 PF11727.8 KEZ42604.1 - 5.1 6.2 34.0 0.31 10.2 10.1 3.2 1 1 4 5 5 5 0 Invariant surface glycoprotein PMEI PF04043.15 KEZ42604.1 - 5.2 7.4 20.2 1.8e+04 -7.6 19.9 4.0 1 1 0 1 1 0 0 Plant invertase/pectin methylesterase inhibitor SKA1 PF07160.12 KEZ42604.1 - 5.4 6.8 19.9 13 5.5 1.4 3.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Sec34 PF04136.15 KEZ42604.1 - 6 6.7 15.9 12 5.8 1.3 4.1 1 1 3 4 4 4 0 Sec34-like family Phage_GP20 PF06810.11 KEZ42604.1 - 7.3 6.4 35.3 5.3 6.8 8.7 3.9 1 1 3 4 4 4 0 Phage minor structural protein GP20 YkyA PF10368.9 KEZ42604.1 - 8 6.1 49.4 4.3 7.0 13.3 4.0 1 1 3 4 4 4 0 Putative cell-wall binding lipoprotein Spectrin PF00435.21 KEZ42604.1 - 8 7.0 19.4 11 6.6 5.7 3.4 1 1 2 3 3 3 0 Spectrin repeat AATF-Che1 PF13339.6 KEZ42604.1 - 10 6.8 17.1 23 5.7 4.8 3.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Steroid_dh PF02544.16 KEZ42605.1 - 2.7e-13 50.1 2.1 5.2e-13 49.2 2.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KEZ42605.1 - 0.0078 15.8 0.6 0.0078 15.8 0.6 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) 2OG-FeII_Oxy_2 PF13532.6 KEZ42606.1 - 9e-11 42.3 0.0 3.6e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 KEZ42607.1 - 6.1e-19 68.4 0.0 3.3e-12 46.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ42607.1 - 2.6e-11 43.8 0.2 2.1e-07 31.4 0.1 4.0 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42607.1 - 7.5e-11 42.0 1.9 0.00018 21.8 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KEZ42607.1 - 4.9e-10 38.8 0.8 0.00061 20.1 0.1 5.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEZ42607.1 - 2.2e-07 31.0 3.0 0.001 19.3 0.2 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) MMR_HSR1_Xtn PF16897.5 KEZ42608.1 - 9.5e-41 138.1 0.8 8.2e-40 135.1 0.5 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KEZ42608.1 - 2.8e-23 81.7 0.1 5.4e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KEZ42608.1 - 1.1e-20 73.8 0.0 6.2e-20 71.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ42608.1 - 7.9e-09 35.2 0.1 3.8e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KEZ42608.1 - 0.00039 20.0 0.2 3.4 7.2 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEZ42608.1 - 0.00059 19.9 0.2 0.16 12.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KEZ42608.1 - 0.0056 15.7 0.3 0.025 13.6 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF211 PF02680.14 KEZ42608.1 - 0.063 13.4 0.2 0.23 11.6 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 RsgA_GTPase PF03193.16 KEZ42608.1 - 0.094 12.6 1.4 6 6.7 0.0 3.0 3 1 1 4 4 4 0 RsgA GTPase Roc PF08477.13 KEZ42608.1 - 0.1 12.8 0.0 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KEZ42608.1 - 0.11 12.8 0.0 1.8 8.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain HTH_Tnp_Tc5 PF03221.16 KEZ42609.1 - 2.3e-12 46.8 0.3 5.7e-12 45.5 0.3 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KEZ42609.1 - 1.6e-08 34.0 0.0 3.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 KEZ42609.1 - 0.00063 19.5 0.0 0.0028 17.4 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 KEZ42609.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PXA PF02194.15 KEZ42610.1 - 2.3e-45 154.8 0.3 4.3e-45 153.9 0.3 1.5 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.6 KEZ42611.1 - 8.9e-30 102.6 6.4 1.9e-29 101.5 6.4 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 KEZ42611.1 - 0.019 15.0 0.4 0.038 14.1 0.4 1.5 1 0 0 1 1 1 0 MYND finger DUF1610 PF07754.11 KEZ42611.1 - 0.64 10.0 4.3 0.23 11.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) MMS1_N PF10433.9 KEZ42612.1 - 1.1e-156 522.3 0.0 2.2e-156 521.3 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KEZ42612.1 - 1.8e-100 336.4 0.0 9.1e-100 334.1 0.0 2.2 3 0 0 3 3 3 1 CPSF A subunit region UBM PF14377.6 KEZ42612.1 - 0.0093 15.4 2.8 0.37 10.3 0.7 2.9 3 0 0 3 3 3 2 Ubiquitin binding region ANAPC4_WD40 PF12894.7 KEZ42612.1 - 0.071 13.4 0.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Mtc PF03820.17 KEZ42613.1 - 4e-119 397.3 0.2 7.1e-119 396.5 0.0 1.4 2 0 0 2 2 2 1 Tricarboxylate carrier zf-Tim10_DDP PF02953.15 KEZ42613.1 - 4.8e-23 80.6 2.4 8.1e-23 79.9 2.4 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4045 PF13254.6 KEZ42614.1 - 3.2e-60 205.0 33.0 7.3e-38 131.3 5.4 7.9 3 2 3 6 6 6 3 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KEZ42614.1 - 2e-08 34.0 0.0 0.025 14.5 0.0 3.8 3 1 0 3 3 3 2 Gelsolin repeat DUF2347 PF09804.9 KEZ42615.1 - 1.6e-87 293.7 0.0 4.2e-85 285.8 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KEZ42615.1 - 8.5e-54 182.8 0.1 4.8e-53 180.3 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 KEZ42615.1 - 0.017 15.1 0.0 0.38 10.7 0.0 2.2 1 1 0 1 1 1 0 Stabilization of polarity axis Avl9 PF09794.9 KEZ42615.1 - 0.23 10.1 0.0 7.5 5.1 0.0 2.4 3 0 0 3 3 3 0 Transport protein Avl9 DnaJ PF00226.31 KEZ42616.1 - 1.7e-17 63.3 1.0 4.2e-17 62.0 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KEZ42616.1 - 1.5e-13 50.6 0.0 9.5e-13 47.9 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain RRN3 PF05327.11 KEZ42616.1 - 4.9 5.6 7.2 8.9 4.7 7.2 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SOG2 PF10428.9 KEZ42617.1 - 5.2 6.1 12.9 6.2 5.9 12.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Acyltransferase PF01553.21 KEZ42618.1 - 4.8e-34 116.9 0.0 7.3e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.21 KEZ42618.1 - 0.047 13.7 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP ATP-synt_DE_N PF02823.16 KEZ42619.1 - 4.6e-17 61.7 0.3 6.2e-17 61.3 0.3 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Vta1_C PF18097.1 KEZ42619.1 - 0.32 10.7 2.1 0.79 9.5 1.1 2.3 2 1 0 2 2 2 0 Vta1 C-terminal domain Arf PF00025.21 KEZ42620.1 - 1.8e-66 222.9 0.0 2e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KEZ42620.1 - 4.5e-11 42.5 0.1 2.1e-07 30.4 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KEZ42620.1 - 1.6e-07 31.6 0.0 5.1e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KEZ42620.1 - 2.4e-07 30.3 0.0 3.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KEZ42620.1 - 2.5e-07 30.4 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 KEZ42620.1 - 4e-07 30.1 0.0 5.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KEZ42620.1 - 1.2e-05 24.8 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KEZ42620.1 - 0.0031 17.1 0.1 0.12 11.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF3336 PF11815.8 KEZ42621.1 - 1.9e-48 163.7 2.4 3e-48 163.0 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KEZ42621.1 - 6.6e-19 68.9 0.7 1.7e-18 67.5 0.1 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase Pkinase PF00069.25 KEZ42622.1 - 3.2e-74 249.6 0.0 4e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42622.1 - 1.1e-37 129.8 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ42622.1 - 6.4e-08 32.3 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 KEZ42622.1 - 0.02 14.5 0.0 0.54 9.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TFIIA PF03153.13 KEZ42622.1 - 0.13 12.2 21.3 0.17 11.9 21.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lectin_leg-like PF03388.13 KEZ42623.1 - 8.1e-67 224.9 0.0 1.1e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KEZ42623.1 - 7e-08 32.7 0.1 1e-07 32.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KEZ42623.1 - 0.00014 21.5 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 Legume lectin domain Pkinase PF00069.25 KEZ42624.1 - 6.1e-51 173.3 0.0 1.3e-50 172.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42624.1 - 4.2e-19 68.8 0.0 3.3e-18 65.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KEZ42624.1 - 0.061 12.9 0.0 0.99 9.0 0.0 2.4 2 1 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 KEZ42624.1 - 0.12 11.3 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro_3_C PF01915.22 KEZ42625.1 - 3.1e-49 167.7 0.0 8.6e-49 166.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ42625.1 - 2.5e-36 125.7 0.0 4.1e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ42625.1 - 5.3e-19 68.1 0.2 1e-18 67.2 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ERG4_ERG24 PF01222.17 KEZ42626.1 - 5.8e-160 532.8 5.3 7.1e-160 532.5 5.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KEZ42626.1 - 0.01 15.4 0.2 0.01 15.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 KEZ42627.1 - 4.7e-16 58.6 0.0 1.1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 KEZ42627.1 - 1.9e-13 50.9 0.0 1.4e-11 44.8 0.0 2.3 2 1 0 2 2 2 2 Autophagy-related protein 27 CIMR PF00878.18 KEZ42627.1 - 3.7e-08 33.6 0.5 1.3e-05 25.2 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PDEase_II PF02112.15 KEZ42628.1 - 6.5e-52 176.7 0.0 6.9e-22 78.0 0.0 3.1 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KEZ42628.1 - 0.065 13.2 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Flavin_Reduct PF01613.18 KEZ42629.1 - 1.8e-20 73.5 0.1 3.4e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KEZ42629.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF447) Med22 PF06179.12 KEZ42631.1 - 9.7e-12 45.0 0.1 1.1e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Pkinase PF00069.25 KEZ42633.1 - 7.1e-55 186.2 0.0 4.1e-48 164.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42633.1 - 7.3e-22 77.9 0.0 7.8e-21 74.5 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ42633.1 - 0.00029 20.3 0.1 0.0035 16.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KEZ42633.1 - 0.03 14.2 2.9 0.14 12.1 2.9 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEZ42633.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Rrn6 PF10214.9 KEZ42633.1 - 0.23 9.9 1.1 0.3 9.5 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nop14 PF04147.12 KEZ42633.1 - 0.78 7.9 11.8 1.1 7.4 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family LCD1 PF09798.9 KEZ42633.1 - 3 6.3 4.9 4.2 5.8 4.9 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Pkinase_fungal PF17667.1 KEZ42633.1 - 9.8 4.8 7.6 22 3.7 7.6 1.5 1 1 0 1 1 1 0 Fungal protein kinase Lung_7-TM_R PF06814.13 KEZ42634.1 - 7e-70 235.6 18.7 8.9e-70 235.3 18.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.6 KEZ42634.1 - 1.3 8.6 10.3 1 9.0 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_28 PF02636.17 KEZ42635.1 - 1e-79 267.9 0.0 1.3e-79 267.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pro_isomerase PF00160.21 KEZ42636.1 - 2.2e-53 180.7 0.1 3.6e-53 180.0 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KEZ42636.1 - 8.8e-06 25.8 0.0 5.6e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 KEZ42636.1 - 0.00062 19.8 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein APH PF01636.23 KEZ42638.1 - 1.3e-09 38.3 0.1 1.7e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ42638.1 - 0.24 10.9 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase AMPK1_CBM PF16561.5 KEZ42639.1 - 6.4e-09 35.9 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Iwr1 PF08574.10 KEZ42640.1 - 4.6e-13 50.0 6.8 4.6e-13 50.0 6.8 2.7 2 0 0 2 2 2 1 Transcription factor Iwr1 HNF-1_N PF04814.13 KEZ42640.1 - 4.6 7.8 6.5 0.76 10.4 1.0 2.3 2 1 1 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pneumo_att_G PF05539.11 KEZ42641.1 - 1.1 8.8 2.9 1.4 8.5 2.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G His_Phos_1 PF00300.22 KEZ42642.1 - 3.1e-18 66.2 0.0 4.2e-17 62.5 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CRIM PF16978.5 KEZ42643.1 - 1.2e-41 142.2 0.0 2.3e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KEZ42643.1 - 3.1e-31 107.9 0.1 5.4e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PH PF00169.29 KEZ42643.1 - 0.0016 18.9 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 PH domain TUG-UBL1 PF11470.8 KEZ42643.1 - 0.013 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 TUG ubiquitin-like domain Zip PF02535.22 KEZ42645.1 - 7.4e-35 120.7 17.5 4.5e-33 114.9 17.5 3.0 1 1 0 1 1 1 1 ZIP Zinc transporter Trypan_PARP PF05887.11 KEZ42645.1 - 0.46 10.5 9.7 11 6.0 11.2 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.32 KEZ42646.1 - 4.9e-37 125.3 22.5 1.3e-06 29.0 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KEZ42646.1 - 1e-12 47.7 0.9 2.2e-12 46.7 0.9 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KEZ42646.1 - 2e-09 37.6 1.0 0.094 13.0 0.0 5.7 1 1 6 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ42646.1 - 2.1e-06 26.7 10.2 0.17 10.5 0.1 6.1 1 1 6 7 7 7 3 Nucleoporin Nup120/160 F-box PF00646.33 KEZ42646.1 - 6.2e-06 25.9 2.5 1.4e-05 24.9 2.5 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KEZ42646.1 - 0.00023 20.6 0.0 0.0086 15.4 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain PQQ_2 PF13360.6 KEZ42646.1 - 0.011 15.4 1.5 0.011 15.4 1.5 2.1 2 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 KEZ42646.1 - 0.026 15.0 2.8 29 5.3 0.0 4.8 5 1 0 5 5 5 0 PQQ-like domain Mcl1_mid PF12341.8 KEZ42646.1 - 0.1 11.9 0.5 1.9 7.8 0.0 2.3 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region PALB2_WD40 PF16756.5 KEZ42646.1 - 0.37 9.7 6.6 1.5 7.6 0.1 3.5 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain E1_dh PF00676.20 KEZ42647.1 - 5.2e-115 383.5 0.1 6.3e-115 383.2 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEZ42647.1 - 0.0043 16.3 0.1 0.0077 15.5 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.21 KEZ42648.1 - 1.6e-60 204.2 0.4 6.3e-48 163.1 0.1 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEZ42648.1 - 1.2e-44 152.7 0.7 3.3e-44 151.3 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KEZ42648.1 - 1.2e-28 99.6 0.0 5e-28 97.6 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KEZ42648.1 - 1.5e-05 25.4 0.1 2.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 RNA ligase Ndc1_Nup PF09531.10 KEZ42648.1 - 0.96 8.1 6.6 1.4 7.5 6.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Voltage_CLC PF00654.20 KEZ42649.1 - 2.6e-87 293.4 29.2 2.6e-87 293.4 29.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KEZ42649.1 - 9.9e-05 22.7 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 CBS domain DUF4644 PF15486.6 KEZ42649.1 - 0.24 11.2 0.9 0.48 10.2 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4644) Neurochondrin PF05536.11 KEZ42650.1 - 8.9e-59 199.4 0.0 3.7e-32 111.5 0.0 2.1 1 1 1 2 2 2 2 Neurochondrin V-ATPase_H_N PF03224.14 KEZ42650.1 - 0.00032 20.1 0.0 0.003 16.9 0.0 2.3 2 1 1 3 3 3 1 V-ATPase subunit H RIX1 PF08167.12 KEZ42650.1 - 0.0027 17.5 0.4 0.0088 15.8 0.4 1.8 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis DUF4487 PF14868.6 KEZ42650.1 - 0.13 11.0 0.2 0.35 9.6 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4487) Ras PF00071.22 KEZ42651.1 - 6.1e-52 175.5 0.0 7.4e-52 175.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ42651.1 - 2.5e-18 66.5 0.0 3.8e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ42651.1 - 9.7e-06 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family tRNA-synt_2 PF00152.20 KEZ42652.1 - 4.6e-87 292.0 0.0 6.2e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEZ42652.1 - 4.1e-08 33.1 0.0 7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KEZ42652.1 - 0.033 14.4 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain His_Phos_2 PF00328.22 KEZ42653.1 - 1.6e-17 64.0 0.0 7e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) MreB_Mbl PF06723.13 KEZ42654.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein 7TM_GPCR_Srw PF10324.9 KEZ42655.1 - 0.012 15.0 1.0 0.019 14.3 1.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw CRPA PF05745.11 KEZ42655.1 - 0.036 14.1 1.0 0.08 13.0 1.0 1.6 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Gtr1_RagA PF04670.12 KEZ42656.1 - 1e-65 221.3 0.1 1.3e-65 221.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KEZ42656.1 - 0.018 14.5 0.1 0.033 13.6 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family ANAPC4 PF12896.7 KEZ42657.1 - 8.4e-67 224.6 0.2 1.3e-66 224.0 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KEZ42657.1 - 8.4e-12 45.2 0.1 3.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEZ42657.1 - 0.026 15.4 0.0 0.19 12.7 0.0 2.6 1 0 0 1 1 1 0 WD domain, G-beta repeat Adap_comp_sub PF00928.21 KEZ42658.1 - 6e-18 65.2 0.1 8.7e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEZ42658.1 - 3e-07 30.5 0.1 6.6e-07 29.4 0.1 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KEZ42658.1 - 0.0075 16.7 0.7 0.016 15.6 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 KEZ42659.1 - 1.7e-08 34.4 0.1 3.3e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 KEZ42660.1 - 1.6e-100 336.0 15.4 1.9e-100 335.8 15.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KEZ42660.1 - 6.8e-05 23.1 5.8 6.8e-05 23.1 5.8 3.2 3 0 0 3 3 3 1 EamA-like transporter family Transmemb_17 PF09799.9 KEZ42660.1 - 7.5 7.2 12.3 0.92 10.1 3.3 2.7 1 1 1 2 2 2 0 Predicted membrane protein Ribosomal_S3_C PF00189.20 KEZ42661.1 - 6.1e-24 84.4 0.6 2.9e-23 82.2 0.1 2.3 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KEZ42661.1 - 6.4e-12 45.1 0.1 1.1e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KEZ42661.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KEZ42661.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus Myotub-related PF06602.14 KEZ42662.1 - 8e-149 495.3 0.0 9.9e-149 495.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PP2C_C PF07830.13 KEZ42662.1 - 0.037 14.5 0.0 0.098 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Y_phosphatase3 PF13350.6 KEZ42662.1 - 0.089 12.7 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family tRNA_synthFbeta PF17759.1 KEZ42663.1 - 1e-47 162.4 0.0 1.5e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KEZ42663.1 - 1.3e-30 105.4 0.6 1.7e-29 101.8 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KEZ42663.1 - 4.5e-25 88.3 0.1 8.2e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KEZ42663.1 - 1.8e-16 60.2 0.0 3.2e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.22 KEZ42664.1 - 8.5e-40 131.4 13.4 0.015 15.5 0.1 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 KEZ42664.1 - 3.1e-34 117.2 3.6 3.8e-10 40.0 0.0 8.2 4 2 4 8 8 8 7 HEAT repeats HEAT_EZ PF13513.6 KEZ42664.1 - 7.9e-13 48.6 3.0 0.025 15.1 0.1 8.0 8 1 1 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 KEZ42664.1 - 7.2e-12 45.6 9.7 1.6e-05 25.0 0.1 5.7 5 1 2 7 7 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEZ42664.1 - 1.6e-10 41.5 1.7 0.022 15.3 0.1 7.0 5 2 4 9 9 9 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KEZ42664.1 - 6.1e-08 31.7 4.1 0.0072 14.9 0.1 5.0 4 1 2 6 6 6 3 Adaptin N terminal region RTP1_C1 PF10363.9 KEZ42664.1 - 1.4e-07 31.7 1.3 0.14 12.3 0.1 5.2 5 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KEZ42664.1 - 0.00094 18.8 3.0 1.2 8.6 0.1 4.4 4 2 2 6 6 6 1 CLASP N terminal M11L PF11099.8 KEZ42664.1 - 0.016 15.5 0.1 3.4 7.9 0.0 3.1 2 1 1 3 3 3 0 Apoptosis regulator M11L like Ecm29 PF13001.7 KEZ42664.1 - 0.016 13.9 3.4 0.19 10.4 0.0 3.8 4 1 0 5 5 5 0 Proteasome stabiliser Proteasom_PSMB PF10508.9 KEZ42664.1 - 0.12 10.8 3.7 0.7 8.3 0.0 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Trp_Tyr_perm PF03222.13 KEZ42664.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.4 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family Arm PF00514.23 KEZ42664.1 - 0.16 12.0 4.5 3.2 7.9 0.0 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 KEZ42664.1 - 2.4 6.8 6.8 0.77 8.5 0.2 3.2 5 0 0 5 5 5 0 Apoptosis inhibitory protein 5 (API5) Methyltransf_31 PF13847.6 KEZ42665.1 - 1.2e-12 47.9 0.0 2.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ42665.1 - 8.3e-08 32.2 0.0 2.8e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42665.1 - 1.6e-07 31.9 0.0 3e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42665.1 - 3.5e-07 30.9 0.0 1.1e-06 29.3 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42665.1 - 2.9e-05 24.6 0.0 6.9e-05 23.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain AdoMet_MTase PF07757.13 KEZ42665.1 - 0.00061 20.1 0.0 0.00093 19.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 KEZ42665.1 - 0.0027 17.3 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KEZ42665.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KEZ42665.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KEZ42665.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB RCC1 PF00415.18 KEZ42667.1 - 9.4e-52 173.4 2.0 2.6e-09 37.6 0.1 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEZ42667.1 - 8.3e-38 127.4 15.3 3.8e-07 29.8 0.0 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 KEZ42667.1 - 0.00035 20.4 0.4 1.5 9.0 0.0 3.6 4 0 0 4 4 4 2 Kelch motif SUKH-3 PF14433.6 KEZ42667.1 - 0.0047 17.4 0.5 17 5.8 0.0 4.4 4 1 0 4 4 4 1 SUKH-3 immunity protein PQQ_3 PF13570.6 KEZ42667.1 - 0.1 13.1 0.8 16 6.2 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain RCC1 PF00415.18 KEZ42668.1 - 7.9e-44 148.1 15.9 9.6e-10 38.9 0.1 8.7 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEZ42668.1 - 6.4e-26 89.6 29.0 9e-09 34.9 0.5 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat BSP_II PF05432.11 KEZ42668.1 - 0.00016 21.5 37.2 0.00016 21.5 37.2 2.5 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 KEZ42668.1 - 0.071 11.3 31.6 0.14 10.4 31.6 1.4 1 0 0 1 1 1 0 Nop14-like family Pro-kuma_activ PF09286.11 KEZ42669.1 - 7.1e-35 120.4 0.0 1.6e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KEZ42669.1 - 1.4e-05 24.5 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family ABC_membrane PF00664.23 KEZ42670.1 - 2.1e-89 299.8 30.5 3.6e-48 164.6 8.9 3.0 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ42670.1 - 5.8e-52 175.8 0.0 1.5e-30 106.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ42670.1 - 1.4e-09 37.8 5.2 0.0036 16.8 0.0 4.4 3 2 1 5 5 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KEZ42670.1 - 8.7e-06 25.8 0.7 0.21 11.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ42670.1 - 0.00029 20.8 0.1 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KEZ42670.1 - 0.0013 19.3 0.1 0.33 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KEZ42670.1 - 0.0025 17.9 1.0 0.39 10.8 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 KEZ42670.1 - 0.0059 17.0 0.5 0.14 12.5 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain ABC_membrane_2 PF06472.15 KEZ42670.1 - 0.0065 15.9 0.1 0.0065 15.9 0.1 2.7 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 AAA_29 PF13555.6 KEZ42670.1 - 0.0077 15.9 0.5 5.6 6.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEZ42670.1 - 0.014 15.8 0.0 0.73 10.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KEZ42670.1 - 0.02 15.0 0.8 0.96 9.5 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_21 PF13304.6 KEZ42670.1 - 0.03 14.2 0.3 6.2 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEZ42670.1 - 0.042 13.6 0.7 0.93 9.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KEZ42670.1 - 0.064 13.0 0.4 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 KEZ42670.1 - 0.093 12.5 0.1 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein MWFE PF15879.5 KEZ42670.1 - 0.11 12.7 0.2 0.69 10.1 0.2 2.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit NB-ARC PF00931.22 KEZ42670.1 - 0.12 11.5 1.7 3.2 6.9 0.3 3.0 2 1 0 2 2 2 0 NB-ARC domain DUP PF00674.18 KEZ42670.1 - 0.21 11.8 1.1 0.78 9.9 1.1 2.0 1 0 0 1 1 1 0 DUP family AAA_22 PF13401.6 KEZ42670.1 - 0.25 11.6 1.0 33 4.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain 60KD_IMP PF02096.20 KEZ42670.1 - 0.65 9.9 4.4 2.1 8.2 4.4 1.8 1 0 0 1 1 1 0 60Kd inner membrane protein NACHT PF05729.12 KEZ42670.1 - 1.1 9.1 3.4 0.88 9.5 0.1 2.4 3 0 0 3 3 3 0 NACHT domain DUF2841 PF11001.8 KEZ42671.1 - 1.5e-41 141.3 4.0 2.6e-41 140.6 4.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SgrT PF15894.5 KEZ42671.1 - 0.13 12.2 0.5 0.33 10.9 0.5 1.6 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT DUF155 PF02582.14 KEZ42672.1 - 4.1e-53 180.1 0.1 5.5e-53 179.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.19 KEZ42673.1 - 1.1e-11 45.0 4.6 1.1e-11 45.0 4.6 2.9 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEZ42673.1 - 5.2e-06 26.9 5.4 5.2e-06 26.9 5.4 2.8 4 0 0 4 4 4 1 HMG-box domain Strep_SA_rep PF06696.11 KEZ42673.1 - 0.0065 16.4 9.6 0.0065 16.4 9.6 2.2 2 0 0 2 2 2 1 Streptococcal surface antigen repeat Sacchrp_dh_NADP PF03435.18 KEZ42674.1 - 5.7e-15 55.7 0.0 1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEZ42674.1 - 0.00094 19.6 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KEZ42674.1 - 0.046 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KEZ42674.1 - 0.16 12.1 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cpn60_TCP1 PF00118.24 KEZ42675.1 - 1.3e-152 508.9 7.7 1.5e-152 508.7 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_1d PF00750.19 KEZ42675.1 - 0.0066 15.4 0.2 0.035 13.0 0.0 2.0 1 1 1 2 2 2 1 tRNA synthetases class I (R) Nitro_FeMo-Co PF02579.17 KEZ42675.1 - 0.019 15.3 0.1 0.078 13.3 0.1 2.0 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor EAL PF00563.20 KEZ42675.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 EAL domain PHD PF00628.29 KEZ42676.1 - 1e-10 41.3 12.2 1.5e-09 37.6 4.9 2.7 2 0 0 2 2 2 2 PHD-finger zf-rbx1 PF12678.7 KEZ42676.1 - 1.6e-08 34.7 9.4 2.7e-06 27.6 0.7 3.1 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEZ42676.1 - 7.3e-08 32.6 17.1 2.4e-07 30.9 1.0 3.5 3 0 0 3 3 3 1 Ring finger domain PHD_2 PF13831.6 KEZ42676.1 - 0.00013 21.4 2.4 0.00013 21.4 2.4 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.6 KEZ42676.1 - 0.00025 20.9 6.7 0.00056 19.8 0.4 3.4 4 0 0 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KEZ42676.1 - 0.00027 20.7 0.8 0.00027 20.7 0.8 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEZ42676.1 - 0.00043 20.1 1.0 0.00043 20.1 1.0 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ42676.1 - 0.00053 19.8 2.7 0.00053 19.8 2.7 3.2 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEZ42676.1 - 0.0011 18.9 4.2 0.031 14.3 0.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KEZ42676.1 - 0.0026 17.6 0.5 0.0026 17.6 0.5 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.6 KEZ42676.1 - 0.003 17.2 4.7 0.004 16.8 1.2 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Zn_ribbon_17 PF17120.5 KEZ42676.1 - 0.0042 16.7 1.1 0.0042 16.7 1.1 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 KEZ42676.1 - 0.025 14.5 2.2 0.025 14.5 2.2 2.8 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 zf-P11 PF03854.14 KEZ42676.1 - 0.38 10.4 3.3 0.48 10.1 0.4 2.3 2 0 0 2 2 2 0 P-11 zinc finger Rad50_zn_hook PF04423.14 KEZ42676.1 - 0.67 9.8 2.8 25 4.8 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1644 PF07800.12 KEZ42676.1 - 0.7 9.9 5.4 3.9 7.5 1.1 3.3 3 1 0 3 3 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.6 KEZ42676.1 - 0.72 9.7 5.1 0.27 11.1 0.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KEZ42676.1 - 0.94 9.7 4.5 1.1 9.5 1.8 2.4 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KEZ42676.1 - 0.98 9.7 4.5 0.47 10.7 0.7 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain DZR PF12773.7 KEZ42676.1 - 1.4 9.0 5.3 12 6.0 2.9 2.8 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_9 PF13901.6 KEZ42676.1 - 3.1 7.7 7.8 9.2 6.2 0.5 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Zf_RING PF16744.5 KEZ42676.1 - 3.3 7.9 8.6 4.6 7.4 2.5 2.8 2 1 0 2 2 2 0 KIAA1045 RING finger AAA PF00004.29 KEZ42677.1 - 2.4e-24 86.2 0.0 4.3e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KEZ42677.1 - 2.1e-11 43.6 0.0 3.2e-10 39.9 0.0 2.9 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 KEZ42677.1 - 4.6e-07 29.3 0.0 7.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KEZ42677.1 - 1e-06 29.3 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ42677.1 - 2.1e-05 25.0 0.0 0.00013 22.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KEZ42677.1 - 0.0002 21.4 0.0 0.00058 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEZ42677.1 - 0.001 19.4 0.0 0.0032 17.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KEZ42677.1 - 0.0012 19.2 0.0 0.0036 17.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 KEZ42677.1 - 0.0038 17.5 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KEZ42677.1 - 0.0086 16.2 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KEZ42677.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEZ42677.1 - 0.015 15.1 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 KEZ42677.1 - 0.033 14.0 0.0 0.078 12.8 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KEZ42677.1 - 0.038 13.1 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 KEZ42677.1 - 0.038 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KEZ42677.1 - 0.053 13.3 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KEZ42677.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 1 0 Cytidylate kinase IstB_IS21 PF01695.17 KEZ42677.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KEZ42677.1 - 0.081 13.0 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KEZ42677.1 - 0.092 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KEZ42677.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KEZ42677.1 - 0.13 12.0 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ42677.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KEZ42677.1 - 0.15 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 KEZ42677.1 - 0.18 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain CPT PF07931.12 KEZ42677.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MRP-L46 PF11788.8 KEZ42678.1 - 9.9e-32 110.2 0.2 2e-31 109.2 0.2 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KEZ42678.1 - 0.0023 18.0 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.20 KEZ42679.1 - 1.8e-48 165.4 0.0 2.7e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Acetyltransf_4 PF13420.7 KEZ42679.1 - 0.062 13.4 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SMC_N PF02463.19 KEZ42680.1 - 2e-58 197.4 30.0 1.8e-57 194.3 30.0 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEZ42680.1 - 3.3e-26 91.9 0.1 1.7e-25 89.6 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEZ42680.1 - 3.8e-17 63.1 4.2 3.2e-09 37.0 0.1 3.6 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ42680.1 - 2.3e-11 44.6 28.2 2.3e-11 44.6 28.2 6.4 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KEZ42680.1 - 4.6e-11 43.0 43.1 4.5e-09 36.5 6.8 4.5 2 2 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 KEZ42680.1 - 0.00053 20.2 0.1 0.0019 18.4 0.1 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit CENP-F_leu_zip PF10473.9 KEZ42680.1 - 0.0029 17.6 3.5 0.0029 17.6 3.5 7.3 2 2 3 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.6 KEZ42680.1 - 0.0031 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 KEZ42680.1 - 0.0049 16.2 4.4 0.0049 16.2 4.4 7.9 2 2 5 8 8 8 1 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 KEZ42680.1 - 0.37 11.3 0.0 0.37 11.3 0.0 6.1 3 2 0 3 3 3 0 ABC transporter DUF3535 PF12054.8 KEZ42681.1 - 1.8e-126 422.9 0.0 3.1e-125 418.9 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KEZ42681.1 - 5e-66 222.8 0.0 1.3e-65 221.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ42681.1 - 2.1e-19 69.9 0.0 8e-19 68.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KEZ42681.1 - 2.5e-18 64.6 9.0 0.0014 18.7 0.0 9.1 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.6 KEZ42681.1 - 8.1e-10 39.0 3.7 0.00021 21.6 0.0 6.8 7 0 0 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KEZ42681.1 - 3.1e-05 24.5 3.9 1.4 9.6 0.0 4.2 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KEZ42681.1 - 0.0033 17.5 0.5 4.1 7.4 0.0 4.1 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KEZ42681.1 - 0.01 16.3 10.6 23 5.6 0.0 8.5 10 0 0 10 10 10 0 HEAT-like repeat UME PF08064.13 KEZ42681.1 - 0.05 13.5 4.7 5.3 7.0 0.3 4.7 4 2 1 5 5 5 0 UME (NUC010) domain CLASP_N PF12348.8 KEZ42681.1 - 0.051 13.1 0.1 15 5.1 0.1 3.5 3 1 0 3 3 3 0 CLASP N terminal IFRD PF05004.13 KEZ42681.1 - 1.4 8.0 3.6 9 5.3 0.0 3.7 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) CDC37_N PF03234.14 KEZ42682.1 - 1.2e-48 165.2 14.9 1.3e-48 165.2 1.4 2.9 3 0 0 3 3 3 2 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KEZ42682.1 - 1.1e-37 128.6 0.7 2.1e-37 127.6 0.1 1.8 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KEZ42682.1 - 1.3e-31 108.7 10.9 4.9e-31 106.8 0.5 2.7 2 0 0 2 2 2 1 Cdc37 C terminal domain AsiA PF09010.10 KEZ42682.1 - 0.092 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Anti-Sigma Factor A Trimer_CC PF08954.11 KEZ42682.1 - 0.23 11.0 3.4 0.49 10.0 1.6 2.5 2 0 0 2 2 2 0 Trimerisation motif ING PF12998.7 KEZ42682.1 - 0.38 11.4 4.6 0.28 11.8 1.1 2.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SPATA1_C PF15743.5 KEZ42682.1 - 0.96 9.5 8.7 0.23 11.5 4.5 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus ALMT PF11744.8 KEZ42682.1 - 6.6 5.4 5.9 12 4.6 5.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter APG17 PF04108.12 KEZ42683.1 - 1.4e-126 422.9 6.7 1.6e-126 422.6 6.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 EzrA PF06160.12 KEZ42683.1 - 0.01 14.1 2.0 0.022 12.9 2.0 1.5 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ATG19_autophagy PF12744.7 KEZ42683.1 - 0.043 13.0 0.2 0.1 11.7 0.2 1.6 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding ZnuA PF01297.17 KEZ42683.1 - 0.07 12.5 0.3 0.18 11.2 0.3 1.7 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic BLOC1_2 PF10046.9 KEZ42683.1 - 0.32 11.3 2.0 2.2 8.7 0.0 3.2 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 KEZ42683.1 - 1.2 9.8 5.2 19 5.9 1.3 3.7 3 1 0 3 3 3 0 Initiation control protein YabA Tektin PF03148.14 KEZ42683.1 - 1.5 7.5 7.8 0.2 10.3 0.1 3.0 3 1 0 4 4 4 0 Tektin family Glyco_hydro_45 PF02015.16 KEZ42684.1 - 1.7e-33 116.3 6.7 2.1e-33 116.1 6.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 2OG-FeII_Oxy PF03171.20 KEZ42685.1 - 0.00013 22.4 0.0 0.00031 21.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KEZ42685.1 - 0.00052 20.8 0.0 0.00081 20.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.32 KEZ42686.1 - 6.1e-45 150.3 14.0 6.2e-07 30.0 0.1 8.6 8 0 0 8 8 8 8 WD domain, G-beta repeat F-box-like PF12937.7 KEZ42686.1 - 5.4e-14 51.8 0.7 9.7e-14 51.0 0.7 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ42686.1 - 8.2e-11 41.5 0.3 1.9e-10 40.4 0.3 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KEZ42686.1 - 8.4e-11 42.0 1.1 0.0084 16.4 0.0 5.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ42686.1 - 4.7e-09 35.4 2.1 0.25 9.9 0.0 4.7 4 1 1 5 5 5 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KEZ42686.1 - 0.00014 21.8 0.1 1.7 8.7 0.0 3.8 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 KEZ42686.1 - 0.00056 19.8 0.0 0.0025 17.7 0.0 2.1 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 KEZ42686.1 - 0.00084 18.8 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 WD40-like domain PRANC PF09372.10 KEZ42686.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 PRANC domain PALB2_WD40 PF16756.5 KEZ42686.1 - 0.77 8.6 3.5 21 3.9 0.1 3.6 2 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Mito_carr PF00153.27 KEZ42687.1 - 1.8e-67 223.3 1.5 1.8e-21 75.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 KEZ42688.1 - 1.1e-36 125.3 0.0 3.7e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein RdRP PF05183.12 KEZ42690.1 - 1.4e-135 453.2 0.0 1.9e-135 452.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fungal_trans PF04082.18 KEZ42691.1 - 3.8e-05 22.9 0.0 6.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 KEZ42692.1 - 3.1e-109 353.8 51.8 9.3e-12 45.3 0.5 11.4 12 0 0 12 12 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42692.1 - 6.3e-39 132.2 19.5 1.4e-05 25.3 0.0 10.6 2 1 9 11 11 10 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ42692.1 - 1.5e-24 86.5 15.8 0.00012 21.1 0.4 9.3 1 1 7 8 8 8 8 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEZ42692.1 - 9.5e-23 81.1 6.6 5.3e-08 33.0 0.2 4.8 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KEZ42692.1 - 2.6e-15 56.5 0.0 0.00061 19.2 0.0 5.8 2 2 2 5 5 5 5 WD40-like domain NACHT PF05729.12 KEZ42692.1 - 2.4e-11 43.8 0.0 6.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 KEZ42692.1 - 3.8e-11 42.3 20.8 0.2 10.2 0.0 9.0 4 2 6 10 10 10 6 Nucleoporin Nup120/160 AAA_16 PF13191.6 KEZ42692.1 - 6.5e-07 29.9 2.0 1e-06 29.3 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KEZ42692.1 - 9.5e-06 24.4 1.3 0.06 11.9 0.0 3.8 1 1 2 4 4 4 2 Cytochrome D1 heme domain CDtoxinA PF03498.14 KEZ42692.1 - 1.6e-05 24.5 3.8 18 4.9 0.1 6.4 1 1 8 9 9 9 0 Cytolethal distending toxin A/C domain CNH PF00780.22 KEZ42692.1 - 3.9e-05 23.4 3.1 31 4.0 0.0 7.0 4 2 5 9 9 9 0 CNH domain potato_inhibit PF00280.18 KEZ42692.1 - 0.00033 21.2 5.4 30 5.4 0.0 7.7 3 2 8 11 11 10 0 Potato inhibitor I family DUF1513 PF07433.11 KEZ42692.1 - 0.00073 18.7 14.7 1.2 8.2 0.2 5.7 1 1 5 6 6 6 1 Protein of unknown function (DUF1513) KAP_NTPase PF07693.14 KEZ42692.1 - 0.017 14.4 1.4 0.028 13.6 0.6 1.6 1 1 1 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 KEZ42692.1 - 0.021 14.7 0.1 0.038 13.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KEZ42692.1 - 0.049 14.2 0.1 0.15 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ42692.1 - 0.071 12.8 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain DUF3050 PF11251.8 KEZ42692.1 - 0.16 11.6 0.0 0.65 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) AAA PF00004.29 KEZ42692.1 - 0.19 12.2 0.0 0.48 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 KEZ42692.1 - 0.32 11.0 16.7 13 5.9 0.0 7.9 10 0 0 10 10 8 0 WD40-like Beta Propeller Repeat Peptidase_C2 PF00648.21 KEZ42693.1 - 1.4e-57 195.0 0.4 5.2e-56 189.8 0.4 2.4 1 1 0 1 1 1 1 Calpain family cysteine protease NicO PF03824.16 KEZ42694.1 - 1.1e-59 202.1 6.4 1.5e-59 201.7 6.4 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein Sulfotransfer_4 PF17784.1 KEZ42695.1 - 4.2e-62 209.8 0.1 5.4e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEZ42695.1 - 0.00051 20.5 0.1 0.051 13.9 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family COX14 PF14880.6 KEZ42695.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Glyco_hydro_7 PF00840.20 KEZ42697.1 - 8e-149 496.0 5.3 9.4e-149 495.8 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 EBP PF05241.12 KEZ42698.1 - 0.002 17.7 3.6 0.0041 16.6 3.6 1.5 1 0 0 1 1 1 1 Emopamil binding protein DUF3439 PF11921.8 KEZ42698.1 - 5.4 7.0 9.1 8.8 6.3 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dynactin_p62 PF05502.13 KEZ42700.1 - 2.2e-192 640.1 0.5 5.8e-192 638.7 0.5 1.6 1 1 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.18 KEZ42701.1 - 3.2e-82 274.8 0.2 3.9e-82 274.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RCC1 PF00415.18 KEZ42702.1 - 2.2e-54 181.9 5.8 1.6e-09 38.2 0.0 7.8 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEZ42702.1 - 2.1e-32 110.3 29.0 7.8e-08 31.9 0.8 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Choline_transpo PF04515.12 KEZ42703.1 - 8.6e-85 284.8 29.0 8.6e-85 284.8 29.0 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KEZ42703.1 - 0.19 12.4 4.8 0.44 11.2 4.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OPT PF03169.15 KEZ42704.1 - 3.4e-167 557.8 48.1 3.9e-167 557.6 48.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 KEZ42705.1 - 7.6e-38 130.3 32.4 7.6e-38 130.3 32.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MAPEG PF01124.18 KEZ42706.1 - 4.5e-18 65.4 1.8 5.1e-18 65.2 1.8 1.1 1 0 0 1 1 1 1 MAPEG family DEAD PF00270.29 KEZ42708.1 - 7.8e-45 152.8 0.1 1.4e-44 151.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2183 PF09949.9 KEZ42708.1 - 2e-31 108.2 0.0 5e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.31 KEZ42708.1 - 1e-27 96.7 0.1 4.4e-27 94.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LNS2 PF08235.13 KEZ42708.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) UTP25 PF06862.12 KEZ42708.1 - 0.19 10.5 0.1 0.99 8.1 0.0 2.1 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CH PF00307.31 KEZ42709.1 - 6.6e-05 23.0 0.0 8.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain F-box-like PF12937.7 KEZ42710.1 - 6.4e-07 29.2 0.2 1.6e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like Velvet PF11754.8 KEZ42711.1 - 1.3e-07 31.8 0.0 1.6e-07 31.6 0.0 1.3 1 1 0 1 1 1 1 Velvet factor Peptidase_S8 PF00082.22 KEZ42712.1 - 5.8e-49 166.9 0.3 8.3e-49 166.4 0.3 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEZ42712.1 - 2.3e-11 44.4 0.0 7.8e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KEZ42712.1 - 7.6e-06 25.9 0.0 3.4e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.6 KEZ42712.1 - 0.11 12.4 0.0 0.42 10.5 0.0 2.0 1 0 0 1 1 1 0 FlgD Ig-like domain ACC_central PF08326.12 KEZ42713.1 - 8.6e-266 883.8 0.0 1.1e-265 883.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KEZ42713.1 - 3.1e-182 606.6 0.0 4e-182 606.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KEZ42713.1 - 3e-52 177.2 0.0 5.6e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEZ42713.1 - 1.3e-27 96.5 0.1 2.6e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ42713.1 - 7.4e-23 80.7 0.0 2.2e-20 72.7 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KEZ42713.1 - 1.2e-16 60.3 0.2 3.1e-16 59.0 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 KEZ42713.1 - 0.0052 17.0 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Dala_Dala_lig_C PF07478.13 KEZ42713.1 - 0.0068 16.0 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KEZ42713.1 - 0.0074 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KEZ42713.1 - 0.021 14.7 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 KEZ42713.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon NUDE_C PF04880.13 KEZ42714.1 - 1.2e-39 136.7 14.9 1.2e-39 136.7 14.9 4.7 2 1 3 5 5 1 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 KEZ42714.1 - 0.00021 21.7 7.8 0.00021 21.7 7.8 4.5 2 1 3 5 5 5 1 Cell division protein ZapB YppF PF14178.6 KEZ42714.1 - 0.14 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 YppF-like protein Fez1 PF06818.15 KEZ42714.1 - 0.2 12.1 29.8 1.5e+02 2.7 27.2 3.2 2 1 0 2 2 2 0 Fez1 DUF4852 PF16144.5 KEZ42714.1 - 0.24 11.6 4.3 0.52 10.4 4.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4852) CENP-F_leu_zip PF10473.9 KEZ42714.1 - 0.29 11.2 37.9 0.41 10.7 7.9 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 KEZ42714.1 - 0.34 11.0 35.6 0.59 10.3 21.4 3.5 2 1 1 3 3 3 0 Tropomyosin like Seryl_tRNA_N PF02403.22 KEZ42714.1 - 0.41 10.9 17.2 0.94 9.7 6.8 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PSII_Pbs27 PF13326.6 KEZ42714.1 - 0.49 10.7 7.6 0.13 12.6 4.2 1.8 2 0 0 2 2 1 0 Photosystem II Pbs27 GAS PF13851.6 KEZ42714.1 - 0.68 9.3 30.3 3.7 6.8 4.4 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding FPP PF05911.11 KEZ42714.1 - 0.79 7.8 28.2 0.02 13.1 13.3 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2046 PF09755.9 KEZ42714.1 - 0.88 8.7 25.8 2.1 7.5 4.7 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein H4 (DUF2046) ADIP PF11559.8 KEZ42714.1 - 1.7 8.8 30.6 2.1 8.4 8.5 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 KEZ42714.1 - 2.7 7.5 32.0 21 4.6 29.0 2.6 2 1 0 2 2 2 0 Intermediate filament protein ERM PF00769.19 KEZ42714.1 - 2.8 7.7 36.5 0.21 11.4 23.1 2.4 2 1 1 3 3 3 0 Ezrin/radixin/moesin family YjbH PF06082.11 KEZ42714.1 - 3.5 6.3 5.8 6 5.6 5.8 1.4 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF745 PF05335.13 KEZ42714.1 - 4.8 6.9 15.7 0.52 10.0 10.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF745) FlxA PF14282.6 KEZ42714.1 - 8.7 6.4 20.8 6.3 6.8 7.4 3.8 2 1 1 4 4 4 0 FlxA-like protein ADH_N PF08240.12 KEZ42715.1 - 3.1e-26 91.4 1.5 4.8e-26 90.8 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ42715.1 - 4.5e-15 55.8 0.0 1.3e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ42715.1 - 0.002 17.5 0.2 0.0035 16.7 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEZ42715.1 - 0.023 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 KEZ42716.1 - 4.8e-29 100.0 10.7 2.6e-06 28.1 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 KEZ42716.1 - 1.8e-09 37.3 1.2 3.1e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KEZ42716.1 - 5.1e-07 29.9 0.1 0.012 15.9 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KEZ42716.1 - 6.2e-07 29.1 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KEZ42716.1 - 0.00012 20.9 0.5 1.5 7.4 0.0 3.4 1 1 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ42716.1 - 0.0021 17.1 0.1 0.024 13.6 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KEZ42716.1 - 0.074 11.6 0.0 0.14 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain F-box_4 PF15966.5 KEZ42716.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 F-box STE PF02200.16 KEZ42716.1 - 0.11 13.0 0.3 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 STE like transcription factor Scs3p PF10261.9 KEZ42717.1 - 1.3e-72 244.3 0.7 1.7e-72 243.9 0.7 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.9 KEZ42717.1 - 4.6e-20 71.5 0.0 1.1e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-binding PF00249.31 KEZ42718.1 - 0.028 14.6 0.1 0.066 13.4 0.1 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEZ42718.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain NAD_binding_6 PF08030.12 KEZ42719.1 - 7.3e-22 78.2 0.0 1.1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEZ42719.1 - 1.3e-21 76.8 0.0 2.4e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KEZ42719.1 - 7.4e-20 71.3 10.2 7.4e-20 71.3 10.2 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KEZ42719.1 - 0.14 12.8 0.0 2.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4780 PF16012.5 KEZ42719.1 - 0.17 11.4 0.0 0.48 9.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) AAA PF00004.29 KEZ42720.1 - 4.5e-18 65.9 0.0 8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CBM_21 PF03370.13 KEZ42721.1 - 4e-30 104.3 0.3 9e-30 103.2 0.3 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KEZ42721.1 - 1.6e-10 41.4 1.2 3.3e-10 40.4 1.2 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) PseudoU_synth_1 PF01416.20 KEZ42722.1 - 1.2e-11 45.0 0.0 1.3e-09 38.5 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase SAGA-Tad1 PF12767.7 KEZ42722.1 - 0.0039 17.0 0.4 0.0082 15.9 0.4 1.6 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF2344 PF10105.9 KEZ42722.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Ndc80_HEC PF03801.13 KEZ42722.1 - 0.042 13.5 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family DCP2 PF05026.13 KEZ42723.1 - 6.9e-30 103.2 0.2 1.2e-29 102.5 0.2 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KEZ42723.1 - 1.5e-18 67.1 0.3 3.5e-18 65.9 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF4112 PF13430.6 KEZ42724.1 - 3.8e-36 123.5 0.3 5e-36 123.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HycH PF07450.11 KEZ42725.1 - 0.019 15.3 0.0 0.031 14.6 0.0 1.3 1 1 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Ribonuc_red_sm PF00268.21 KEZ42726.1 - 3.8e-123 410.4 2.2 4.7e-123 410.1 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 KEZ42727.1 - 4.3e-34 116.8 1.3 6.5e-34 116.2 1.3 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) SesA PF17107.5 KEZ42728.1 - 2.7e-06 27.6 1.3 7.4e-06 26.1 0.8 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KEZ42728.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins WD40 PF00400.32 KEZ42729.1 - 7.3e-14 51.9 1.4 1.9e-06 28.5 0.1 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42729.1 - 0.00014 22.1 0.0 0.48 10.8 0.0 4.1 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ42729.1 - 0.039 12.6 0.1 0.093 11.4 0.1 1.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Mito_carr PF00153.27 KEZ42730.1 - 7.4e-55 182.9 1.1 7.6e-19 67.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 KEZ42730.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family CTU2 PF10288.9 KEZ42731.1 - 4.5e-10 39.8 0.1 2.6e-07 30.9 0.0 3.1 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 KEZ42731.1 - 0.024 14.4 0.0 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 PP-loop family LAS2 PF15792.5 KEZ42732.1 - 4.5 7.9 9.0 2.8 8.5 1.4 3.2 3 0 0 3 3 3 0 Lung adenoma susceptibility protein 2 WD40 PF00400.32 KEZ42734.1 - 9.7e-12 45.2 13.3 0.00027 21.7 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat PALB2_WD40 PF16756.5 KEZ42734.1 - 0.017 14.0 0.7 4.7 6.0 0.1 2.6 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Mcl1_mid PF12341.8 KEZ42735.1 - 7.3e-99 330.9 0.0 1.2e-96 323.6 0.0 2.4 2 0 0 2 2 2 2 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KEZ42735.1 - 3.9e-20 71.8 5.4 4.8e-08 33.5 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42735.1 - 1.9e-19 69.8 0.0 0.0017 18.6 0.0 8.0 2 1 6 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KEZ42735.1 - 3.8e-08 32.8 0.0 3.1e-06 26.5 0.1 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 KEZ42735.1 - 7.8e-06 25.9 0.5 0.00052 20.0 0.1 2.9 1 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KEZ42735.1 - 0.00059 19.7 0.2 29 4.7 0.0 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KEZ42735.1 - 0.0064 15.5 0.1 2 7.3 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KEZ42735.1 - 0.074 11.0 0.1 0.24 9.4 0.1 1.8 1 1 0 1 1 1 0 IKI3 family PQQ_3 PF13570.6 KEZ42735.1 - 0.78 10.3 3.8 18 6.0 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain DNA_pol_alpha_N PF12254.8 KEZ42735.1 - 5 7.3 8.4 17 5.6 8.1 2.0 1 1 1 2 2 2 0 DNA polymerase alpha subunit p180 N terminal HSF_DNA-bind PF00447.17 KEZ42736.1 - 5.1e-06 27.0 0.0 7.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding SOG2 PF10428.9 KEZ42736.1 - 0.09 12.0 13.2 0.11 11.7 13.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein GREB1 PF15782.5 KEZ42736.1 - 0.74 6.9 4.7 0.78 6.8 4.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer HSF_DNA-bind PF00447.17 KEZ42737.1 - 1.7e-05 25.4 0.0 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Asp PF00026.23 KEZ42738.1 - 9.5e-16 58.1 0.0 4e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF4690 PF15756.5 KEZ42738.1 - 0.017 15.7 0.9 0.093 13.3 0.0 2.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Gram_pos_anchor PF00746.21 KEZ42738.1 - 5.1 7.1 6.1 14 5.8 6.1 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Ndc1_Nup PF09531.10 KEZ42739.1 - 3.8e-189 630.3 0.1 4.3e-189 630.2 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 KEZ42740.1 - 7.2e-19 68.0 2.9 7.2e-19 68.0 2.9 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KEZ42740.1 - 1.4e-14 53.8 3.0 3.4e-14 52.6 1.2 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KEZ42740.1 - 0.00024 20.8 12.9 0.0032 17.2 12.9 2.2 1 1 0 1 1 1 1 Syntaxin T3SSipB PF16535.5 KEZ42740.1 - 0.011 16.3 5.6 0.011 16.3 5.6 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF2154 PF09922.9 KEZ42740.1 - 0.015 15.2 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Cell wall-active antibiotics response 4TMS YvqF Prominin PF05478.11 KEZ42740.1 - 0.038 11.9 9.1 0.45 8.4 1.4 2.0 1 1 1 2 2 2 0 Prominin DUF3552 PF12072.8 KEZ42740.1 - 0.12 11.8 13.8 0.071 12.5 12.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Telomerase_RBD PF12009.8 KEZ42740.1 - 0.12 12.4 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain DUF4618 PF15397.6 KEZ42740.1 - 0.14 11.5 9.3 4.3 6.7 7.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF16 PF01519.16 KEZ42740.1 - 0.2 12.2 12.5 0.59 10.7 0.9 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF883 PF05957.13 KEZ42740.1 - 0.84 10.3 12.9 5 7.8 0.3 3.5 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) ALG11_N PF15924.5 KEZ42741.1 - 1.6e-81 273.3 0.0 2.3e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KEZ42741.1 - 1.1e-23 83.6 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ42741.1 - 1e-10 42.1 0.0 1.9e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ42741.1 - 0.00059 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 G_glu_transpept PF01019.21 KEZ42742.1 - 4.1e-169 563.6 0.0 4.8e-169 563.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1344 PF07076.11 KEZ42742.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) P22_CoatProtein PF11651.8 KEZ42742.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 UNC45-central PF11701.8 KEZ42743.1 - 4.6e-54 182.5 0.4 9.1e-52 175.1 0.0 3.1 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 KEZ42743.1 - 4.4e-05 23.8 14.4 0.16 12.3 2.7 6.3 4 1 4 8 8 8 4 HEAT repeats HEAT PF02985.22 KEZ42743.1 - 0.00015 21.8 9.2 0.15 12.4 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.23 KEZ42743.1 - 0.0048 16.9 14.3 16 5.7 0.2 7.4 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEZ42743.1 - 0.011 16.2 12.1 0.88 10.1 0.2 6.0 7 1 0 7 7 7 0 HEAT-like repeat CLASP_N PF12348.8 KEZ42743.1 - 0.012 15.1 0.1 0.078 12.5 0.0 2.2 3 0 0 3 3 3 0 CLASP N terminal Nipped-B_C PF12830.7 KEZ42743.1 - 0.15 12.0 1.3 0.78 9.6 0.2 2.6 3 1 0 3 3 3 0 Sister chromatid cohesion C-terminus DUF4754 PF15946.5 KEZ42743.1 - 0.23 11.7 0.9 2 8.7 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4754) Asparaginase_2 PF01112.18 KEZ42744.1 - 1.3e-39 136.0 6.2 3.7e-25 88.6 0.0 2.4 2 1 0 2 2 2 2 Asparaginase Actin PF00022.19 KEZ42745.1 - 1.6e-85 287.2 0.0 2.9e-52 177.6 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KEZ42745.1 - 0.09 11.6 0.1 2.8 6.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein HMA PF00403.26 KEZ42746.1 - 3.7e-16 59.3 0.3 4.9e-16 58.9 0.3 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Glyco_hydro_61 PF03443.14 KEZ42747.1 - 2.4e-52 177.8 0.0 4.5e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4366 PF14283.6 KEZ42747.1 - 0.38 10.8 2.3 0.68 10.0 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Macoilin PF09726.9 KEZ42747.1 - 1.1 7.7 2.8 1.4 7.3 2.8 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 KEZ42747.1 - 2.5 6.6 7.2 3.1 6.3 7.2 1.1 1 0 0 1 1 1 0 Hamartin protein DUF1180 PF06679.12 KEZ42747.1 - 6 7.3 12.5 11 6.4 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Thiolase_N PF00108.23 KEZ42749.1 - 1.5e-13 50.7 3.0 2.2e-11 43.7 0.2 3.5 3 1 0 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ42749.1 - 2.5e-12 46.5 0.9 1.2e-11 44.4 0.2 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KEZ42749.1 - 0.00013 21.8 0.2 0.014 15.2 0.3 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KEZ42749.1 - 0.015 15.3 0.1 1 9.4 0.0 3.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Fungal_trans PF04082.18 KEZ42750.1 - 2.5e-13 49.7 0.2 4.8e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42750.1 - 4.1e-06 26.8 18.9 9.3e-06 25.7 18.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tcf25 PF04910.14 KEZ42751.1 - 7e-62 209.5 1.5 1e-61 209.0 1.5 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Nop53 PF07767.11 KEZ42751.1 - 0.69 9.2 21.8 1.4 8.2 21.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TEX19 PF15553.6 KEZ42751.1 - 1.2 9.1 4.2 3.3 7.7 4.2 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 Herpes_DNAp_acc PF04929.12 KEZ42751.1 - 2.7 6.9 9.4 4.1 6.3 9.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_C37 PF05416.12 KEZ42751.1 - 4.1 5.8 7.8 8 4.8 7.8 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase CDC45 PF02724.14 KEZ42751.1 - 8.5 4.5 13.5 14 3.9 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein LSM14 PF12701.7 KEZ42752.1 - 3e-32 110.6 0.4 5.5e-32 109.7 0.4 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KEZ42752.1 - 1.4e-22 80.5 4.0 1.4e-22 80.5 4.0 2.3 3 0 0 3 3 3 1 FDF domain SM-ATX PF14438.6 KEZ42752.1 - 9.8e-07 28.8 0.1 2.6e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM PF01423.22 KEZ42752.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 LSM domain Pyr_redox_2 PF07992.14 KEZ42753.1 - 7.6e-61 205.9 2.0 1.2e-60 205.2 2.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEZ42753.1 - 5.5e-33 113.5 0.8 1.4e-32 112.2 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEZ42753.1 - 1.3e-18 67.3 4.7 3.7e-17 62.7 0.1 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ42753.1 - 2.2e-18 66.5 0.2 3.1e-18 66.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ42753.1 - 0.00059 19.2 0.1 0.0013 18.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KEZ42753.1 - 0.0015 17.3 4.3 0.84 8.3 0.0 3.2 2 1 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 KEZ42753.1 - 0.0021 17.5 0.5 0.006 16.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KEZ42753.1 - 0.0029 16.8 0.1 0.4 9.8 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KEZ42753.1 - 0.0065 15.6 0.2 0.04 13.0 0.1 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEZ42753.1 - 0.042 12.9 6.5 0.59 9.2 0.6 3.0 4 0 0 4 4 4 0 FAD binding domain 3HCDH_N PF02737.18 KEZ42753.1 - 0.067 13.1 1.8 0.089 12.7 0.0 2.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KEZ42753.1 - 0.27 10.5 2.1 1.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KEZ42753.1 - 1.1 9.6 4.9 0.23 11.7 0.9 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEZ42753.1 - 1.2 8.3 4.0 2 7.6 0.6 2.7 2 1 1 3 3 3 0 FAD binding domain HA2 PF04408.23 KEZ42754.1 - 1.3e-16 60.9 0.5 3.9e-16 59.3 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KEZ42754.1 - 1.1e-15 57.7 0.0 2.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KEZ42754.1 - 1.1e-12 48.3 0.0 2.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KEZ42754.1 - 0.00012 21.9 0.2 0.00056 19.7 0.2 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEZ42754.1 - 0.00028 21.2 0.9 0.0027 18.0 0.2 2.8 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.6 KEZ42754.1 - 0.0018 18.6 0.0 0.0092 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ42754.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KEZ42754.1 - 0.018 14.6 0.7 0.57 9.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KEZ42754.1 - 0.026 15.0 0.1 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain TFIIE-A_C PF11521.8 KEZ42754.1 - 0.073 13.4 1.6 0.16 12.3 1.6 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha SRP54 PF00448.22 KEZ42754.1 - 0.083 12.5 0.8 2.2 7.9 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KEZ42754.1 - 0.13 11.8 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ank_2 PF12796.7 KEZ42755.1 - 9.9e-44 147.8 0.5 8e-11 42.4 0.0 7.0 6 2 1 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ42755.1 - 1.4e-33 114.8 2.9 1.1e-08 35.5 0.0 9.1 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ42755.1 - 6.5e-32 109.2 5.0 4e-05 23.8 0.1 8.7 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42755.1 - 2.2e-27 94.2 9.7 9.2e-05 22.7 0.1 10.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 KEZ42755.1 - 4.6e-27 91.1 10.6 0.00025 21.2 0.0 10.8 11 0 0 11 11 11 7 Ankyrin repeat Pkinase PF00069.25 KEZ42755.1 - 3.5e-22 79.0 0.0 5.4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42755.1 - 2.1e-20 73.1 0.0 3.5e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF294 PF03445.13 KEZ42755.1 - 0.0097 15.7 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 Sel1 PF08238.12 KEZ42755.1 - 0.093 13.4 0.0 0.35 11.6 0.0 2.1 1 0 0 1 1 1 0 Sel1 repeat HeLo PF14479.6 KEZ42756.1 - 1.7e-16 60.6 0.3 2.7e-16 60.0 0.3 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 KEZ42756.1 - 1.3e-06 28.0 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42756.1 - 6.7e-05 22.3 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SKG6 PF08693.10 KEZ42758.1 - 3e-06 26.5 4.5 5.4e-06 25.7 4.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KEZ42758.1 - 0.0015 18.5 0.7 0.0063 16.4 0.7 2.0 1 1 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.12 KEZ42758.1 - 0.0026 17.4 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Phage_holin_2_4 PF16082.5 KEZ42758.1 - 0.0097 15.6 1.4 0.01 15.5 0.1 1.7 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like DUF4448 PF14610.6 KEZ42758.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Saf_2TM PF18303.1 KEZ42758.1 - 0.034 13.7 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4381 PF14316.6 KEZ42758.1 - 0.15 12.3 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) COesterase PF00135.28 KEZ42759.1 - 3.7e-85 286.7 0.0 4.7e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ42759.1 - 7.2e-07 29.3 1.3 0.0092 15.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold FAM199X PF15814.5 KEZ42760.1 - 3.5 6.6 12.0 9.4 5.2 12.0 1.7 1 0 0 1 1 1 0 Protein family FAM199X DUF3632 PF12311.8 KEZ42761.1 - 9.5e-28 97.8 1.2 1.3e-27 97.3 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DASH_Dad2 PF08654.10 KEZ42762.1 - 4.4e-27 94.4 11.0 4.5e-27 94.4 5.2 2.5 2 1 0 2 2 2 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 KEZ42762.1 - 0.018 14.8 0.4 0.028 14.2 0.4 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 DHC_N2 PF08393.13 KEZ42762.1 - 0.058 12.5 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DUF2090 PF09863.9 KEZ42762.1 - 0.09 11.8 0.2 0.1 11.6 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) SLX9 PF15341.6 KEZ42762.1 - 0.11 12.9 1.3 0.14 12.5 1.3 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF4842 PF16130.5 KEZ42762.1 - 0.13 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4842) NmrA PF05368.13 KEZ42763.1 - 2.2e-27 96.2 0.0 2.9e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ42763.1 - 7.4e-20 71.6 0.0 1.7e-19 70.5 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEZ42763.1 - 4.1e-05 23.8 0.1 0.00035 20.8 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KEZ42763.1 - 0.00066 19.2 0.1 0.0077 15.7 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KEZ42763.1 - 0.024 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Urocanase PF01175.18 KEZ42763.1 - 0.046 13.4 0.0 3.6 7.2 0.0 2.5 2 1 0 2 2 2 0 Urocanase Rossmann-like domain Semialdhyde_dh PF01118.24 KEZ42763.1 - 0.086 13.3 0.2 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEZ42763.1 - 0.13 11.2 0.0 0.61 9.0 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shugoshin_N PF07558.11 KEZ42764.1 - 6e-16 58.0 5.9 6e-16 58.0 5.9 2.4 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KEZ42764.1 - 4.5e-11 42.3 6.7 4.5e-11 42.3 6.7 3.6 3 0 0 3 3 3 1 Shugoshin C terminus DivIC PF04977.15 KEZ42764.1 - 0.046 13.5 2.2 3.1 7.6 1.6 2.8 2 0 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 KEZ42764.1 - 0.38 10.8 5.5 1 9.5 5.5 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Metallophos_2 PF12850.7 KEZ42765.1 - 1.7e-12 47.8 0.0 2.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KEZ42765.1 - 0.058 13.9 0.0 1.3 9.5 0.0 2.1 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Aminotran_5 PF00266.19 KEZ42766.1 - 4.6e-29 101.5 0.0 5.7e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CRM1_C PF08767.11 KEZ42767.1 - 1.7e-131 438.2 1.5 1.7e-131 438.2 1.5 3.0 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KEZ42767.1 - 4.7e-40 137.1 9.0 4.7e-40 137.1 9.0 3.5 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KEZ42767.1 - 1.8e-33 114.0 4.2 5.2e-33 112.5 4.2 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KEZ42767.1 - 9.6e-28 96.1 3.7 2.4e-27 94.8 1.4 3.0 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KEZ42767.1 - 1.7e-19 69.0 1.1 4.6e-19 67.6 1.1 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KEZ42767.1 - 2e-10 40.4 0.3 1e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Sec7_N PF12783.7 KEZ42767.1 - 0.00085 19.3 14.9 0.2 11.6 2.4 4.2 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3385 PF11865.8 KEZ42767.1 - 0.013 15.4 7.7 0.25 11.2 0.1 4.8 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 KEZ42767.1 - 0.083 12.1 0.1 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Hemocyanin, copper containing domain Vac14_Fab1_bd PF12755.7 KEZ42767.1 - 0.1 13.2 3.6 1.9 9.1 0.0 4.5 6 0 0 6 6 5 0 Vacuolar 14 Fab1-binding region FliH PF02108.16 KEZ42767.1 - 0.29 11.2 1.6 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Flagellar assembly protein FliH Prolamin_like PF05617.11 KEZ42767.1 - 4.8 7.4 5.3 5.4 7.3 0.1 3.4 4 0 0 4 4 3 0 Prolamin-like SapB_2 PF03489.17 KEZ42768.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 2 Fungal_trans PF04082.18 KEZ42769.1 - 0.036 13.1 0.1 0.1 11.6 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain PatG_C PF18065.1 KEZ42769.1 - 0.15 12.0 0.1 0.43 10.6 0.1 1.7 1 1 1 2 2 2 0 PatG C-terminal RGS PF00615.19 KEZ42770.1 - 6.3e-05 23.2 0.0 0.00022 21.5 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_23 PF13489.6 KEZ42771.1 - 5.8e-13 49.0 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42771.1 - 2.9e-09 37.5 0.0 8.3e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42771.1 - 1.7e-07 31.8 0.0 5.3e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42771.1 - 0.00063 20.4 0.0 0.0022 18.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ42771.1 - 0.00099 18.5 0.0 0.0023 17.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Aldolase_II PF00596.21 KEZ42772.1 - 7.7e-51 172.7 0.1 9.5e-51 172.4 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain dCMP_cyt_deam_1 PF00383.23 KEZ42773.1 - 7.5e-21 73.9 1.1 2.3e-20 72.3 0.7 2.0 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEZ42773.1 - 8.2e-17 61.3 0.1 1.9e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KEZ42773.1 - 0.00042 20.4 0.6 0.023 14.8 0.1 2.3 2 0 0 2 2 2 1 Bd3614-like deaminase Inv-AAD PF18785.1 KEZ42773.1 - 0.055 13.3 0.5 0.87 9.5 0.1 2.2 1 1 0 2 2 2 0 Invertebrate-AID/APOBEC-deaminase SH3_1 PF00018.28 KEZ42774.1 - 9.4e-14 50.8 0.1 1.9e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 KEZ42774.1 - 4.8e-13 49.3 0.0 7.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KEZ42774.1 - 1.8e-12 46.9 0.0 3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEZ42774.1 - 6e-11 41.9 0.1 1.2e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 KEZ42774.1 - 0.0045 16.7 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3104) Caskin-Pro-rich PF16907.5 KEZ42774.1 - 0.0072 16.8 1.0 0.0072 16.8 1.0 2.7 3 0 0 3 3 3 1 Proline rich region of Caskin proteins Bot1p PF12298.8 KEZ42776.1 - 5.4e-50 169.9 1.2 6.8e-50 169.6 0.8 1.4 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Sortilin-Vps10 PF15902.5 KEZ42776.1 - 0.0035 16.2 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, HTH_28 PF13518.6 KEZ42776.1 - 4.2 7.6 8.3 38 4.5 0.1 4.1 5 0 0 5 5 5 0 Helix-turn-helix domain Response_reg PF00072.24 KEZ42777.1 - 5.1e-19 68.5 0.0 1.2e-13 51.2 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.9 KEZ42778.1 - 5.6e-25 88.6 16.2 3.5e-24 86.1 16.2 1.9 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) L51_S25_CI-B8 PF05047.16 KEZ42779.1 - 5.8e-12 45.3 0.1 8.1e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 KEZ42780.1 - 1.6e-46 157.0 0.8 2.4e-46 156.4 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 KEZ42780.1 - 0.0017 18.4 0.3 0.0024 17.9 0.3 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange Ank_3 PF13606.6 KEZ42781.1 - 4.1e-09 35.9 0.1 0.0097 16.4 0.0 3.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KEZ42781.1 - 1.4e-07 31.9 0.0 7.5e-06 26.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ42781.1 - 3.6e-07 30.7 0.0 3.2e-06 27.7 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ42781.1 - 5.2e-06 26.6 0.1 0.24 11.8 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42781.1 - 0.00024 21.4 0.0 0.14 12.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat HSP70 PF00012.20 KEZ42782.1 - 2.5e-11 42.5 0.2 7.5e-10 37.6 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KEZ42782.1 - 0.02 13.7 0.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_2 PF03727.16 KEZ42783.1 - 6.8e-77 258.1 0.0 9.6e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEZ42783.1 - 8.8e-77 257.5 0.1 1.3e-76 256.9 0.1 1.3 1 0 0 1 1 1 1 Hexokinase DUF2732 PF10809.8 KEZ42784.1 - 0.0077 16.1 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2732) DGCR6 PF07324.11 KEZ42784.1 - 0.064 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein zf_UBZ PF18439.1 KEZ42784.1 - 0.17 11.5 2.2 1.9 8.2 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 KEZ42784.1 - 1.9 8.2 7.5 0.21 11.2 3.2 1.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.21 KEZ42785.1 - 6.7e-52 175.9 0.0 7.6e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 KEZ42785.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) Peptidase_A22B PF04258.13 KEZ42786.1 - 1.3e-55 189.0 11.2 9.3e-39 133.6 3.7 2.6 3 0 0 3 3 3 2 Signal peptide peptidase CrgA PF06781.12 KEZ42786.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.8 4 0 0 4 4 4 0 Cell division protein CrgA FAM176 PF14851.6 KEZ42786.1 - 0.86 9.3 4.2 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 FAM176 family ACPS PF01648.20 KEZ42787.1 - 6.5e-13 48.8 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SRP-alpha_N PF04086.13 KEZ42788.1 - 1.9e-76 257.8 0.1 2.9e-76 257.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KEZ42788.1 - 2.8e-52 177.2 0.1 4.6e-52 176.5 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KEZ42788.1 - 8.5e-09 35.5 0.3 2.9e-08 33.8 0.3 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KEZ42788.1 - 1.4e-05 24.2 0.0 2.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KEZ42788.1 - 0.0012 18.6 0.1 0.0012 18.6 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KEZ42788.1 - 0.0028 18.1 0.0 0.01 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KEZ42788.1 - 0.011 15.3 0.1 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KEZ42788.1 - 0.041 14.4 0.0 0.19 12.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 KEZ42788.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ42788.1 - 0.062 13.4 0.1 0.25 11.5 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ42788.1 - 0.067 13.6 0.1 0.27 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 KEZ42788.1 - 0.074 13.1 0.5 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain CinA PF02464.17 KEZ42788.1 - 0.12 11.9 0.2 0.12 11.9 0.2 1.9 2 0 0 2 2 2 0 Competence-damaged protein YIF1 PF03878.15 KEZ42789.1 - 9.5e-80 267.6 4.4 2.1e-50 171.5 0.2 2.0 1 1 1 2 2 2 2 YIF1 Yip1 PF04893.17 KEZ42789.1 - 0.18 11.5 7.7 0.55 9.9 7.7 1.8 1 1 0 1 1 1 0 Yip1 domain Amidase PF01425.21 KEZ42790.1 - 1.1e-48 166.3 0.0 1.4e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 KEZ42791.1 - 1.2e-46 159.3 48.6 6.3e-46 156.9 31.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ42791.1 - 9.5e-11 41.2 8.7 9.5e-11 41.2 8.7 2.5 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KEZ42791.1 - 5.1e-06 26.0 5.5 5.1e-06 26.0 5.5 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KEZ42791.1 - 0.0076 14.7 0.5 0.0076 14.7 0.5 1.7 1 1 0 2 2 2 1 Transmembrane secretion effector DHHC PF01529.20 KEZ42791.1 - 0.22 11.6 6.7 3.6 7.7 0.0 3.6 2 1 2 4 4 4 0 DHHC palmitoyltransferase AMP-binding PF00501.28 KEZ42792.1 - 5.4e-78 262.5 0.0 8.4e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KEZ42792.1 - 1.5e-63 214.8 0.0 3e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ42792.1 - 3.9e-53 180.0 0.0 8.6e-52 175.7 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KEZ42792.1 - 8.8e-48 163.1 0.0 1.4e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.20 KEZ42792.1 - 5.9e-47 160.4 0.0 1.2e-46 159.4 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 KEZ42792.1 - 5.2e-40 137.9 0.0 9.2e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEZ42792.1 - 7e-31 106.7 1.0 1.2e-30 106.0 0.2 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KEZ42792.1 - 7e-23 81.1 0.0 1.5e-21 76.7 0.0 2.8 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KEZ42792.1 - 1.6e-20 73.2 0.2 7.6e-12 45.4 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KEZ42792.1 - 3.9e-19 69.2 0.0 1.1e-18 67.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEZ42792.1 - 1.5e-14 54.4 0.0 3.7e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KEZ42792.1 - 5.3e-12 46.3 0.0 1.9e-11 44.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KEZ42792.1 - 5.7e-12 45.6 0.0 6.9e-09 35.5 0.0 3.1 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEZ42792.1 - 1.8e-11 43.9 0.0 9.4e-09 35.0 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Fungal_trans PF04082.18 KEZ42792.1 - 8e-10 38.2 0.0 1.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 KEZ42792.1 - 9.7e-10 39.0 0.0 2.8e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Zn_clus PF00172.18 KEZ42792.1 - 3.8e-08 33.3 10.5 7.2e-08 32.4 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KEZ42792.1 - 5.5e-08 32.8 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42792.1 - 6.5e-07 29.3 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RmlD_sub_bind PF04321.17 KEZ42792.1 - 0.00028 20.1 0.0 0.0037 16.4 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain Thiolase_N PF00108.23 KEZ42792.1 - 0.00045 19.7 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.24 KEZ42792.1 - 0.0012 19.3 0.0 0.027 14.9 0.0 2.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AMP-binding_C PF13193.6 KEZ42792.1 - 0.0025 18.8 0.0 0.0066 17.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ubie_methyltran PF01209.18 KEZ42792.1 - 0.0025 17.2 0.0 0.0089 15.4 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 KEZ42792.1 - 0.061 12.3 0.0 0.34 9.9 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mpv17_PMP22 PF04117.12 KEZ42793.1 - 1.3e-12 47.8 1.9 1.3e-12 47.8 1.9 2.6 3 0 0 3 3 3 1 Mpv17 / PMP22 family DUF3852 PF12963.7 KEZ42793.1 - 0.03 14.6 1.4 3.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) ARPC4 PF05856.12 KEZ42794.1 - 1.5e-74 249.1 4.5 1.7e-74 249.0 4.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) CRAL_TRIO PF00650.20 KEZ42796.1 - 2.5e-13 50.0 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEZ42796.1 - 3.2e-08 33.6 0.0 6.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SET PF00856.28 KEZ42797.1 - 3.6e-15 56.8 1.1 3.6e-15 56.8 1.1 3.3 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KEZ42797.1 - 5.5e-06 26.3 5.9 5.5e-06 26.3 5.9 2.0 2 0 0 2 2 2 1 AWS domain Lge1 PF11488.8 KEZ42797.1 - 0.052 13.7 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DHHC PF01529.20 KEZ42798.1 - 1.7e-26 92.9 4.4 3.7e-26 91.8 0.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-CRD PF17979.1 KEZ42798.1 - 0.038 14.1 1.2 0.062 13.4 1.2 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions ABC2_membrane_3 PF12698.7 KEZ42798.1 - 0.44 9.6 11.9 0.69 9.0 2.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4106 PF13388.6 KEZ42798.1 - 0.95 8.6 7.3 1.4 8.0 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Sugar_tr PF00083.24 KEZ42798.1 - 5.4 5.7 14.1 0.014 14.2 4.1 1.6 2 0 0 2 2 2 0 Sugar (and other) transporter IMS PF00817.20 KEZ42799.1 - 3.1e-39 134.4 0.0 5.1e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 KEZ42799.1 - 1.3e-10 40.7 0.1 1.3e-10 40.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 KEZ42799.1 - 1.4e-08 35.5 0.0 2.9e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-C2H2 PF00096.26 KEZ42799.1 - 0.0039 17.6 0.3 0.011 16.1 0.3 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type IMS_HHH PF11798.8 KEZ42799.1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-met PF12874.7 KEZ42799.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type IBN_N PF03810.19 KEZ42801.1 - 4e-13 49.1 0.7 4.9e-11 42.4 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 KEZ42801.1 - 1.6e-08 33.8 0.1 3.7e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 KEZ42801.1 - 0.00015 21.8 2.9 0.00074 19.6 0.0 3.4 4 0 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.15 KEZ42801.1 - 0.0019 16.8 0.5 0.089 11.3 0.0 3.5 4 0 0 4 4 4 1 CAS/CSE protein, C-terminus GRIP PF01465.20 KEZ42801.1 - 0.0025 17.7 0.1 0.025 14.5 0.0 2.8 2 0 0 2 2 2 1 GRIP domain HEAT_2 PF13646.6 KEZ42801.1 - 0.0028 18.0 2.6 0.13 12.7 0.5 3.5 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 KEZ42801.1 - 0.18 12.2 1.1 1.2 9.6 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat Pkinase PF00069.25 KEZ42803.1 - 5.9e-50 170.1 0.0 8.2e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42803.1 - 7.8e-26 90.9 0.1 1.8e-24 86.4 0.1 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ42803.1 - 0.02 14.2 0.0 0.081 12.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KEZ42803.1 - 0.085 11.6 0.1 0.19 10.4 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase ISN1 PF06437.11 KEZ42804.1 - 1.1e-195 650.4 0.0 1.2e-195 650.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF1902 PF08972.11 KEZ42804.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) MMM1 PF10296.9 KEZ42805.1 - 0.00026 20.1 0.0 0.00026 20.1 0.0 2.7 2 1 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 KEZ42805.1 - 0.013 15.9 0.0 0.051 14.0 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Macoilin PF09726.9 KEZ42805.1 - 0.051 12.1 5.0 0.08 11.5 5.0 1.3 1 0 0 1 1 1 0 Macoilin family Autophagy_N PF03986.13 KEZ42806.1 - 1.1e-42 145.2 0.9 3.5e-42 143.6 0.0 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KEZ42806.1 - 4.8e-16 58.0 0.6 1e-15 56.9 0.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KEZ42806.1 - 6.3e-16 58.7 0.1 1.1e-15 57.9 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF349 PF03993.12 KEZ42806.1 - 0.52 10.6 3.7 0.88 9.9 3.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) rhaM PF05336.13 KEZ42807.1 - 2e-37 127.5 0.2 2.3e-37 127.3 0.2 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase ELP6 PF09807.9 KEZ42810.1 - 0.00041 19.9 0.1 0.00083 18.9 0.0 1.5 1 1 1 2 2 2 1 Elongation complex protein 6 SNARE_assoc PF09335.11 KEZ42810.1 - 0.14 12.7 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein Ribosomal_L37e PF01907.19 KEZ42811.1 - 5.6e-28 96.9 11.8 8.2e-28 96.3 11.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KEZ42811.1 - 0.01 15.9 1.1 0.016 15.2 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C4pol PF14260.6 KEZ42811.1 - 0.067 13.7 2.7 0.096 13.2 2.5 1.4 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta HypA PF01155.19 KEZ42811.1 - 0.093 12.8 0.9 0.12 12.4 0.9 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1258 PF06869.12 KEZ42811.1 - 0.11 12.0 0.4 0.11 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) NRDD PF13597.6 KEZ42811.1 - 0.12 11.1 1.2 0.15 10.8 1.2 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase zf-RING_10 PF16685.5 KEZ42811.1 - 0.15 12.2 2.7 0.19 11.9 2.7 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 KEZ42811.1 - 0.15 11.5 1.9 0.31 10.5 1.9 1.5 1 1 0 1 1 1 0 zinc-ribbon domain UPF0016 PF01169.19 KEZ42812.1 - 1.5e-39 134.2 25.1 3.8e-20 72.0 6.3 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF3357 PF11837.8 KEZ42812.1 - 0.038 14.5 2.6 6 7.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) WD40 PF00400.32 KEZ42813.1 - 1.6e-16 60.4 13.9 0.0003 21.5 0.4 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PD40 PF07676.12 KEZ42813.1 - 0.083 12.9 0.5 0.32 11.0 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KEZ42813.1 - 0.14 10.7 0.7 9.6 4.6 0.0 3.0 2 1 2 4 4 4 0 Cytochrome D1 heme domain RRM_1 PF00076.22 KEZ42814.1 - 0.00065 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lin-8 PF03353.15 KEZ42814.1 - 0.94 9.0 3.8 1.1 8.8 3.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ANAPC5 PF12862.7 KEZ42815.1 - 7.2e-31 106.1 3.1 7.2e-31 106.1 3.1 2.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KEZ42815.1 - 0.0014 18.5 2.6 1.1 9.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ42815.1 - 0.0028 18.1 5.8 0.05 14.2 0.7 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4351 PF14261.6 KEZ42815.1 - 0.0066 16.5 0.4 0.024 14.7 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4351) TPR_2 PF07719.17 KEZ42815.1 - 0.014 15.4 2.5 33 4.9 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ42815.1 - 4.4 8.0 17.0 2.1 9.1 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_L21e PF01157.18 KEZ42816.1 - 7.1e-45 151.0 3.0 1.1e-44 150.4 3.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Nif11 PF07862.11 KEZ42816.1 - 0.11 12.9 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Nif11 domain DUF5486 PF17588.2 KEZ42816.1 - 0.22 11.4 2.0 3.8 7.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5486) S4 PF01479.25 KEZ42817.1 - 2.3e-12 46.4 0.9 2.3e-12 46.4 0.9 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KEZ42817.1 - 7.1e-06 26.8 0.0 1.2e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 KEZ42817.1 - 0.081 13.1 0.3 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation EST1_DNA_bind PF10373.9 KEZ42818.1 - 0.00051 19.6 0.0 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Amastin PF07344.11 KEZ42819.1 - 0.9 9.4 13.2 0.29 11.0 1.1 2.7 3 0 0 3 3 3 0 Amastin surface glycoprotein bZIP_2 PF07716.15 KEZ42820.1 - 0.001 19.1 8.5 0.0018 18.3 8.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF4675 PF15720.5 KEZ42820.1 - 0.016 15.0 2.1 0.026 14.3 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) bZIP_1 PF00170.21 KEZ42820.1 - 0.022 14.9 7.7 0.042 13.9 7.7 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 KEZ42820.1 - 2.6 8.6 9.7 4.2 8.0 9.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Helo_like_N PF17111.5 KEZ42822.1 - 1.5e-07 31.0 2.4 3.4e-07 29.8 1.4 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TPR_12 PF13424.6 KEZ42822.1 - 7.6e-05 22.9 0.2 0.44 10.9 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat NPV_P10 PF05531.12 KEZ42822.1 - 0.00099 19.5 1.1 0.0038 17.6 1.1 2.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein TPR_19 PF14559.6 KEZ42822.1 - 0.022 15.3 0.2 0.4 11.2 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ42822.1 - 0.043 14.0 2.7 1.5 9.1 0.3 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1374 PF07118.11 KEZ42822.1 - 0.057 13.9 0.3 7.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) APG17 PF04108.12 KEZ42822.1 - 1.1 8.3 4.5 0.53 9.3 1.9 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF4795 PF16043.5 KEZ42822.1 - 2.3 7.8 4.6 0.88 9.1 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) ANTH PF07651.16 KEZ42823.1 - 6.9e-82 274.5 0.0 6.9e-82 274.5 0.0 2.5 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 KEZ42823.1 - 4e-55 186.3 8.5 4e-55 186.3 8.5 6.5 5 3 2 7 7 7 2 I/LWEQ domain ENTH PF01417.20 KEZ42823.1 - 0.012 15.7 0.3 0.084 12.9 0.0 2.7 2 1 0 2 2 2 0 ENTH domain Fez1 PF06818.15 KEZ42823.1 - 0.014 15.9 5.1 0.014 15.9 5.1 4.3 2 1 2 4 4 4 0 Fez1 Corona_S2 PF01601.16 KEZ42823.1 - 0.5 8.8 4.2 2 6.8 0.0 2.5 1 1 0 2 2 2 0 Coronavirus S2 glycoprotein T2SSF PF00482.23 KEZ42823.1 - 0.8 9.7 7.3 1.5 8.8 2.0 3.9 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F MATalpha_HMGbox PF04769.12 KEZ42824.1 - 3.8e-55 186.3 0.0 5.1e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box NOA36 PF06524.12 KEZ42825.1 - 8.8e-05 22.0 5.7 0.00011 21.6 5.7 1.5 1 0 0 1 1 1 1 NOA36 protein Pox_Ag35 PF03286.14 KEZ42825.1 - 0.03 14.1 12.3 0.049 13.4 12.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 KEZ42825.1 - 0.086 12.9 11.1 0.15 12.1 11.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RPN2_C PF18004.1 KEZ42825.1 - 0.13 12.2 4.7 0.18 11.7 4.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SDA1 PF05285.12 KEZ42825.1 - 0.27 10.6 17.7 0.31 10.4 17.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEZ42825.1 - 0.76 7.9 22.2 0.85 7.7 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 KEZ42825.1 - 1.1 8.0 5.3 1.2 7.9 5.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFB6 PF17110.5 KEZ42825.1 - 1.4 8.7 8.5 2.2 8.0 8.5 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 KEZ42825.1 - 1.5 7.0 17.8 10 4.3 19.7 1.4 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 KEZ42825.1 - 2.1 7.0 3.7 2.5 6.8 3.7 1.1 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 KEZ42825.1 - 2.3 7.7 16.2 3.5 7.1 16.2 1.4 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 KEZ42825.1 - 2.4 8.0 15.4 3.1 7.6 15.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Paf1 PF03985.13 KEZ42825.1 - 2.9 6.8 18.7 3.8 6.4 18.7 1.1 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 KEZ42825.1 - 5.2 6.7 13.5 13 5.4 13.5 1.7 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 KEZ42825.1 - 6.2 5.7 6.7 7.3 5.5 6.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sporozoite_P67 PF05642.11 KEZ42825.1 - 7.3 4.5 10.7 10 4.1 10.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.14 KEZ42825.1 - 8.6 6.8 8.4 1.4 9.3 4.6 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 COX6A PF02046.15 KEZ42826.1 - 3.8e-52 175.5 1.6 4.5e-52 175.3 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa MCM_bind PF09739.9 KEZ42826.1 - 0.0089 14.5 0.0 0.011 14.2 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor dsDNA_bind PF01984.20 KEZ42827.1 - 5.8e-40 136.0 18.9 6.7e-40 135.8 18.9 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Fes1 PF08609.10 KEZ42827.1 - 0.016 16.1 1.9 0.016 16.1 1.9 1.9 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 cwf18 PF08315.12 KEZ42827.1 - 0.027 15.1 7.4 0.038 14.6 7.4 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF4615 PF15393.6 KEZ42827.1 - 0.028 15.0 1.3 0.028 15.0 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) LAMTOR PF15454.6 KEZ42827.1 - 0.24 12.0 6.9 0.19 12.3 1.4 2.2 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator CDT1_C PF16679.5 KEZ42827.1 - 0.41 11.1 6.9 0.62 10.5 6.9 1.3 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Peptidase_C58 PF03543.14 KEZ42827.1 - 0.91 9.2 6.0 1.2 8.7 6.0 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen MFS_1 PF07690.16 KEZ42828.1 - 6.6e-36 124.0 48.5 2.3e-35 122.2 48.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4360 PF14273.6 KEZ42831.1 - 5.4e-10 39.4 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) HypA PF01155.19 KEZ42832.1 - 0.12 12.4 1.3 0.22 11.6 1.3 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FeoC PF09012.10 KEZ42832.1 - 0.52 10.4 0.1 0.52 10.4 0.1 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator SurE PF01975.17 KEZ42834.1 - 1.3e-28 100.1 0.2 2.7e-28 99.1 0.1 1.5 1 1 1 2 2 2 1 Survival protein SurE Cu_amine_oxid PF01179.20 KEZ42835.1 - 1e-159 531.8 0.0 1.4e-159 531.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KEZ42835.1 - 1.3e-10 41.3 0.2 2.6e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KEZ42835.1 - 0.014 15.8 0.1 0.053 13.9 0.0 2.0 2 0 0 2 2 2 0 Copper amine oxidase, N3 domain Ank_2 PF12796.7 KEZ42836.1 - 1.5e-27 96.0 0.3 8.6e-13 48.7 0.0 5.0 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ42836.1 - 9.3e-20 70.4 4.2 3.4e-12 46.4 0.1 6.1 4 2 3 7 7 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KEZ42836.1 - 1.4e-15 56.9 6.7 1.1e-05 25.6 0.3 6.1 6 1 0 6 6 5 2 Ankyrin repeat Ank_3 PF13606.6 KEZ42836.1 - 4.3e-15 54.3 0.9 0.0054 17.1 0.0 7.4 8 0 0 8 8 6 2 Ankyrin repeat Ank_4 PF13637.6 KEZ42836.1 - 2.7e-14 53.3 3.9 1.9e-10 41.1 0.1 5.6 5 1 1 6 6 5 2 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ42836.1 - 3.9e-08 33.4 0.0 3.1e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ42836.1 - 2.1e-07 31.5 1.6 3.2e-06 27.6 0.0 3.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT_N PF17100.5 KEZ42836.1 - 1e-06 28.8 1.0 1e-06 28.8 1.0 1.7 2 0 0 2 2 1 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 KEZ42836.1 - 0.0001 22.6 0.0 0.00089 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KEZ42836.1 - 0.025 14.3 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KEZ42836.1 - 0.032 13.4 0.0 0.33 10.1 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 KEZ42836.1 - 0.035 14.5 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Baculo_PEP_C PF04513.12 KEZ42836.1 - 0.075 13.1 3.2 0.21 11.6 0.6 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 KEZ42836.1 - 0.1 11.9 2.5 0.16 11.2 0.3 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Helo_like_N PF17111.5 KEZ42836.1 - 0.11 11.8 0.8 18 4.6 0.0 2.7 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins FliD_C PF07195.12 KEZ42836.1 - 0.12 11.7 0.6 15 4.9 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Peptidase_M28 PF04389.17 KEZ42837.1 - 3.3e-39 134.6 0.0 5.1e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEZ42837.1 - 1.1e-09 38.2 0.1 1.1e-09 38.2 0.1 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 KEZ42837.1 - 0.00018 21.3 0.0 0.00043 20.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KEZ42837.1 - 0.0079 15.3 0.0 0.051 12.6 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Myosin_N PF02736.19 KEZ42837.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain MFS_1 PF07690.16 KEZ42839.1 - 1e-13 50.9 13.5 1e-12 47.6 15.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 KEZ42839.1 - 0.0023 15.9 0.0 0.0033 15.4 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF308 PF03729.13 KEZ42839.1 - 9.6 6.6 12.0 35 4.8 9.5 2.6 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) MFS_1 PF07690.16 KEZ42840.1 - 8.6e-32 110.4 69.8 9.2e-18 64.3 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ42840.1 - 0.011 14.6 2.2 0.011 14.6 2.2 3.1 2 1 1 3 3 3 0 MFS_1 like family CoxIIa PF08113.11 KEZ42840.1 - 1.2 9.0 6.1 1.1 9.1 0.1 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IIa family FAD_binding_4 PF01565.23 KEZ42841.1 - 5.6e-20 71.5 2.6 1.5e-19 70.1 2.1 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEZ42841.1 - 0.0017 18.4 1.3 0.0038 17.3 1.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like CsgF PF10614.9 KEZ42841.1 - 0.18 12.0 2.0 0.32 11.2 0.3 2.1 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Jiraiya PF15038.6 KEZ42842.1 - 0.97 8.8 5.2 2.7 7.4 5.0 1.8 1 1 0 1 1 1 0 Jiraiya MFS_1 PF07690.16 KEZ42843.1 - 1.2e-17 63.9 19.1 1.5e-17 63.6 19.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_10 PF00331.20 KEZ42845.1 - 4.6e-99 331.6 0.2 5.2e-99 331.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_3_C PF01915.22 KEZ42847.1 - 6.8e-55 186.2 0.0 1.1e-54 185.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ42847.1 - 1.2e-35 123.5 0.0 1.8e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ42847.1 - 4.9e-20 71.4 0.3 1.5e-19 69.8 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain Lgl_C PF08596.10 KEZ42848.1 - 2.3e-120 401.9 0.0 5.7e-120 400.6 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KEZ42848.1 - 5.1e-09 36.6 1.5 0.0032 18.3 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ42848.1 - 1.2e-06 28.7 0.0 0.23 11.8 0.0 4.8 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2 PF00096.26 KEZ42850.1 - 1.2e-06 28.6 4.3 0.00047 20.5 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ42850.1 - 0.0037 18.0 5.2 0.018 15.9 0.6 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEZ42850.1 - 0.07 13.2 0.4 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KEZ42850.1 - 0.077 13.7 0.3 0.12 13.1 0.3 1.2 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Amidohydro_2 PF04909.14 KEZ42851.1 - 5.2e-09 36.3 0.0 9.1e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KEZ42851.1 - 1.1e-06 28.2 0.0 2.8e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 KEZ42851.1 - 0.017 15.6 0.1 0.065 13.7 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain NAD_binding_6 PF08030.12 KEZ42851.1 - 0.2 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Piwi PF02171.17 KEZ42852.1 - 7.6e-83 278.2 0.0 1e-82 277.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KEZ42852.1 - 8e-19 68.6 0.0 2e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KEZ42852.1 - 4e-12 46.3 0.0 9.2e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KEZ42852.1 - 7.7e-12 44.7 0.0 2.5e-11 43.1 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KEZ42852.1 - 4.8e-09 36.1 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KEZ42852.1 - 2e-07 31.2 0.1 5.9e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Suf PF05843.14 KEZ42853.1 - 6.7e-87 292.2 4.9 4.1e-85 286.3 0.1 4.4 3 2 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KEZ42853.1 - 0.00023 21.7 10.2 0.017 15.9 0.3 5.7 6 1 1 7 7 7 2 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 KEZ42854.1 - 1.2e-72 242.9 0.0 1.5e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone CorA PF01544.18 KEZ42856.1 - 4.7e-12 45.8 0.1 8.6e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RasGAP PF00616.19 KEZ42857.1 - 1.2e-59 201.5 0.1 5.1e-59 199.5 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KEZ42857.1 - 4.3e-28 98.2 4.6 4.3e-28 98.2 4.6 2.5 2 0 0 2 2 2 1 RasGAP C-terminus YabA PF06156.13 KEZ42857.1 - 1.7 9.3 6.6 6.3 7.5 0.6 2.9 2 0 0 2 2 2 0 Initiation control protein YabA Glyco_hydro_43 PF04616.14 KEZ42858.1 - 4.6e-16 59.0 2.2 7.3e-16 58.3 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pyocin_S PF06958.12 KEZ42858.1 - 0.017 15.7 0.1 0.034 14.7 0.1 1.4 1 0 0 1 1 1 0 S-type Pyocin Big_7 PF17957.1 KEZ42858.1 - 0.062 14.1 0.5 0.27 12.0 0.5 2.1 1 0 0 1 1 1 0 Bacterial Ig domain IBR PF01485.21 KEZ42859.1 - 4.4e-22 78.1 46.3 1.2e-11 44.7 6.4 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KEZ42859.1 - 3.6e-05 24.0 6.4 3.6e-05 24.0 6.4 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KEZ42859.1 - 5.1e-05 23.0 4.5 5.1e-05 23.0 4.5 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ42859.1 - 0.00031 20.5 5.4 0.00031 20.5 5.4 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ42859.1 - 0.0042 17.1 32.9 0.0045 17.0 4.1 3.8 3 1 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KEZ42859.1 - 0.012 15.5 8.1 0.012 15.5 8.1 4.2 3 1 0 3 3 3 0 zinc-RING finger domain UN_NPL4 PF11543.8 KEZ42859.1 - 0.014 15.8 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C3HC4_4 PF15227.6 KEZ42859.1 - 0.06 13.5 0.2 0.06 13.5 0.2 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Redoxin PF08534.10 KEZ42860.1 - 6.7e-14 51.8 0.0 8.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KEZ42860.1 - 0.0013 18.7 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family XPG_N PF00752.17 KEZ42861.1 - 5.6e-25 87.8 0.0 1e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KEZ42861.1 - 2.7e-23 82.1 0.0 5.5e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KEZ42861.1 - 0.00067 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KEZ42861.1 - 0.042 14.4 0.0 0.084 13.5 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold MAM33 PF02330.16 KEZ42862.1 - 9.2e-69 231.6 4.5 1.2e-68 231.2 4.5 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Oxysterol_BP PF01237.18 KEZ42863.1 - 2.9e-50 171.2 0.0 2.9e-40 138.3 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein Imm27 PF15590.6 KEZ42863.1 - 0.15 11.8 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 27 CP2 PF04516.15 KEZ42864.1 - 2.9e-79 265.6 0.0 5e-79 264.8 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor AKNA PF12443.8 KEZ42864.1 - 0.033 14.8 0.5 0.08 13.6 0.5 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor Atg14 PF10186.9 KEZ42864.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MFS_1 PF07690.16 KEZ42865.1 - 3.8e-27 95.1 30.7 3.8e-27 95.1 30.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ42865.1 - 0.0013 17.7 8.9 0.0013 17.7 8.9 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ42865.1 - 0.49 8.8 6.4 0.17 10.3 2.4 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF167 PF02594.16 KEZ42866.1 - 1.5e-21 76.3 1.6 2.1e-21 75.8 0.8 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 Ribosomal_L37ae PF01780.19 KEZ42867.1 - 2.6e-39 133.2 5.5 2.8e-39 133.1 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KEZ42867.1 - 0.0032 17.6 1.6 0.0046 17.1 1.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain C1_2 PF03107.16 KEZ42867.1 - 0.11 12.8 1.8 6.6 7.1 2.1 2.1 1 1 1 2 2 2 0 C1 domain Zn_ribbon_SprT PF17283.2 KEZ42867.1 - 0.17 11.8 5.3 0.49 10.4 5.3 1.8 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KEZ42867.1 - 0.22 11.5 3.7 0.39 10.7 3.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 KEZ42867.1 - 0.29 11.2 4.6 3.7 7.6 0.3 2.2 1 1 1 2 2 2 0 BED zinc finger A2L_zn_ribbon PF08792.10 KEZ42867.1 - 0.41 10.4 2.8 10 5.9 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain HAD_SAK_1 PF10307.9 KEZ42868.1 - 4e-73 245.6 0.0 5.5e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins W2 PF02020.18 KEZ42869.1 - 1.2e-20 73.5 3.4 3.4e-20 72.0 3.4 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KEZ42869.1 - 2.5e-07 30.2 13.4 0.0029 17.2 3.6 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ42869.1 - 0.00076 19.2 0.7 0.00076 19.2 0.7 3.2 2 1 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KEZ42869.1 - 0.0013 17.0 0.3 0.002 16.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 KEZ42869.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase NTP_transf_3 PF12804.7 KEZ42869.1 - 0.017 15.4 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.12 KEZ42869.1 - 0.021 13.8 0.5 0.07 12.1 0.5 1.7 1 1 0 1 1 1 0 L-fucokinase HNH_2 PF13391.6 KEZ42870.1 - 1e-10 41.6 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Response_reg PF00072.24 KEZ42871.1 - 4.9e-23 81.4 0.0 1.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.17 KEZ42871.1 - 0.0013 19.3 0.0 0.0031 18.1 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding ATG16 PF08614.11 KEZ42871.1 - 0.002 18.4 9.8 0.0034 17.6 9.8 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) betaPIX_CC PF16523.5 KEZ42871.1 - 0.0033 17.2 0.4 0.019 14.8 0.2 2.2 2 0 0 2 2 2 1 betaPIX coiled coil ZapB PF06005.12 KEZ42871.1 - 0.02 15.4 5.2 0.054 13.9 5.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB RRN3 PF05327.11 KEZ42871.1 - 0.021 13.4 0.2 0.03 12.9 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DivIC PF04977.15 KEZ42871.1 - 0.055 13.2 4.3 0.14 11.9 4.3 1.6 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.19 KEZ42871.1 - 0.058 11.3 3.3 0.078 10.9 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.19 KEZ42871.1 - 0.064 12.9 1.0 0.12 12.1 1.0 1.3 1 0 0 1 1 1 0 GrpE DUF484 PF04340.12 KEZ42871.1 - 0.094 12.4 0.9 0.28 10.9 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF484 SlyX PF04102.12 KEZ42871.1 - 0.096 13.3 5.2 0.35 11.5 5.2 2.0 1 0 0 1 1 1 0 SlyX PK_C PF02887.16 KEZ42871.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Allexi_40kDa PF05549.11 KEZ42871.1 - 0.16 11.5 1.8 0.27 10.7 1.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein CCDC106 PF15794.5 KEZ42871.1 - 0.45 10.2 6.2 0.15 11.7 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 YabA PF06156.13 KEZ42871.1 - 0.55 10.9 4.5 0.66 10.6 3.6 1.6 1 1 0 1 1 1 0 Initiation control protein YabA LUC7 PF03194.15 KEZ42871.1 - 1.5 8.4 7.5 2.3 7.8 7.5 1.1 1 0 0 1 1 1 0 LUC7 N_terminus CENP-H PF05837.12 KEZ42871.1 - 1.9 9.0 8.1 1.1 9.7 6.1 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 KEZ42871.1 - 3.6 6.8 12.7 5.6 6.2 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Axin_b-cat_bind PF08833.10 KEZ42871.1 - 4.2 7.6 6.1 8.4 6.6 1.7 2.9 1 1 1 2 2 2 0 Axin beta-catenin binding domain DNA_primase_S PF01896.19 KEZ42872.1 - 3e-61 206.6 0.1 4.3e-61 206.0 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit Tim17 PF02466.19 KEZ42873.1 - 0.00015 22.1 7.7 0.00038 20.8 7.7 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TauE PF01925.19 KEZ42873.1 - 0.091 12.4 7.3 0.13 11.9 7.3 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Gly-zipper_YMGG PF13441.6 KEZ42873.1 - 4.1 7.2 18.7 48 3.8 10.6 2.6 1 1 1 2 2 2 0 YMGG-like Gly-zipper UCH PF00443.29 KEZ42874.1 - 1.6e-32 113.0 0.0 3.7e-32 111.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ42874.1 - 2.1e-07 30.9 1.0 0.0015 18.2 0.1 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KEZ42874.1 - 1.2e-06 28.3 0.6 0.011 15.6 0.1 3.0 3 0 0 3 3 3 2 A repeated domain in UCH-protein Tyrosinase PF00264.20 KEZ42877.1 - 6.8e-50 170.4 0.0 1e-49 169.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase LSM PF01423.22 KEZ42878.1 - 2.9e-20 71.7 0.0 3.2e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Carb_anhydrase PF00194.21 KEZ42879.1 - 8.9e-28 97.5 0.0 1.1e-12 48.1 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase DPBB_1 PF03330.18 KEZ42880.1 - 6.8e-07 29.5 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Xan_ur_permease PF00860.20 KEZ42881.1 - 2.3e-20 72.6 34.4 2.7e-12 46.1 14.6 2.9 2 1 1 3 3 3 2 Permease family Xan_ur_permease PF00860.20 KEZ42883.1 - 4e-59 200.3 33.0 2.1e-58 197.9 31.2 2.2 2 1 0 2 2 2 1 Permease family NDUF_B12 PF08122.12 KEZ42883.1 - 0.046 13.8 0.2 2.1 8.5 0.0 3.2 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DOPA_dioxygen PF08883.11 KEZ42884.1 - 3.8e-42 142.8 0.0 4.7e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family GATase PF00117.28 KEZ42885.1 - 6e-36 124.0 0.0 9.1e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KEZ42885.1 - 1.3e-33 114.9 0.2 2.7e-33 113.9 0.2 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KEZ42885.1 - 9.2e-10 38.0 0.0 9.8e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KEZ42885.1 - 5.5e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KEZ42885.1 - 0.00037 19.4 0.1 0.0012 17.8 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KEZ42885.1 - 0.00058 19.4 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 KEZ42885.1 - 0.0027 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Arginosuc_synth PF00764.19 KEZ42885.1 - 0.011 15.1 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 KEZ42885.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 KEZ42885.1 - 0.037 13.6 0.0 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Methyltransf_23 PF13489.6 KEZ42886.1 - 2.7e-21 76.1 0.0 5e-21 75.2 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42886.1 - 1.7e-12 47.8 0.0 4e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42886.1 - 6e-11 42.9 0.0 1.2e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42886.1 - 5.7e-10 39.8 0.0 3.2e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42886.1 - 1.4e-07 31.4 0.0 2.9e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ42886.1 - 0.00019 20.8 0.0 0.59 9.4 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ42886.1 - 0.0011 19.1 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KEZ42886.1 - 0.0012 18.2 0.0 0.0092 15.3 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KEZ42886.1 - 0.0014 18.1 1.2 0.0015 18.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KEZ42886.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KEZ42886.1 - 0.032 13.5 0.0 0.07 12.4 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fungal_trans_2 PF11951.8 KEZ42888.1 - 1.3e-21 76.8 0.0 1.6e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ42888.1 - 1.6e-05 25.0 9.0 2.9e-05 24.1 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COQ7 PF03232.13 KEZ42888.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 EBP PF05241.12 KEZ42889.1 - 6.9e-56 188.5 8.3 8.3e-56 188.2 8.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein CFEM PF05730.11 KEZ42891.1 - 2.5e-14 53.1 9.8 4.1e-14 52.4 9.8 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 KEZ42891.1 - 0.0065 16.7 2.3 0.0065 16.7 2.3 1.9 2 0 0 2 2 2 1 Gamma-thionin family Defensin_2 PF01097.18 KEZ42891.1 - 0.0087 16.0 1.7 0.03 14.3 1.7 1.9 1 0 0 1 1 1 1 Arthropod defensin FA_desaturase PF00487.24 KEZ42892.1 - 0.13 12.1 3.0 4.8 6.9 2.0 2.3 2 1 0 2 2 2 0 Fatty acid desaturase DUF1218 PF06749.12 KEZ42893.1 - 0.038 14.5 7.6 0.039 14.5 0.5 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1218) Claudin_2 PF13903.6 KEZ42893.1 - 0.059 13.1 8.2 0.05 13.3 1.3 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF202 PF02656.15 KEZ42893.1 - 0.74 10.3 9.4 0.27 11.7 2.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Bax1-I PF01027.20 KEZ42893.1 - 0.75 9.6 7.7 2.2 8.1 7.9 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF5345 PF17280.2 KEZ42893.1 - 8.8 6.4 7.2 1.8 8.6 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5345) Acyl_transf_3 PF01757.22 KEZ42894.1 - 2.1e-19 69.8 27.9 3.1e-18 66.0 26.9 2.5 1 1 1 2 2 2 1 Acyltransferase family IL6Ra-bind PF09240.10 KEZ42895.1 - 0.18 12.2 0.2 0.41 11.1 0.1 1.5 1 1 0 1 1 1 0 Interleukin-6 receptor alpha chain, binding Glyco_hydro_7 PF00840.20 KEZ42896.1 - 3.4e-186 619.2 12.0 3.8e-186 619.0 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 E1-E2_ATPase PF00122.20 KEZ42897.1 - 2.9e-33 114.9 23.5 5.8e-29 100.9 0.4 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEZ42897.1 - 4.7e-28 98.1 1.9 4.7e-28 98.1 1.9 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEZ42897.1 - 6.1e-21 75.7 0.1 2.6e-19 70.4 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ42897.1 - 8.6e-16 57.8 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEZ42897.1 - 3.8e-15 55.3 0.0 1e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ42897.1 - 5.8e-06 26.2 1.2 4e-05 23.5 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_10 PF00331.20 KEZ42900.1 - 1.6e-99 333.1 0.0 1.8e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Beta-prism_lec PF16458.5 KEZ42900.1 - 0.011 15.7 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 Beta-prism lectin Peptidase_M3 PF01432.20 KEZ42901.1 - 5.2e-88 296.3 0.0 6.9e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Pro_CA PF00484.19 KEZ42901.1 - 5.2e-10 39.8 0.0 1.3e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Carbonic anhydrase BLI1 PF17324.2 KEZ42901.1 - 0.071 13.8 0.1 0.24 12.1 0.1 1.8 1 0 0 1 1 1 0 BLOC-1 interactor 1 DUF768 PF05589.11 KEZ42901.1 - 0.13 12.3 0.1 2 8.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF768) HGTP_anticodon PF03129.20 KEZ42902.1 - 1.4e-20 73.2 0.4 5.5e-20 71.3 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KEZ42902.1 - 2.4e-07 30.9 0.1 5.6e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Med26_M PF15694.5 KEZ42902.1 - 0.0042 17.2 2.4 0.0065 16.6 2.4 1.2 1 0 0 1 1 1 1 Mediator complex subunit 26 middle domain TPT PF03151.16 KEZ42903.1 - 4.6e-09 36.0 16.8 1.4e-08 34.5 16.8 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEZ42903.1 - 4.8e-08 33.3 31.5 1.6e-07 31.6 13.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family GDP_Man_Dehyd PF16363.5 KEZ42904.1 - 1.1e-69 235.4 0.0 1.3e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEZ42904.1 - 4.1e-57 193.4 0.0 5.1e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ42904.1 - 9.9e-24 84.0 0.0 1e-22 80.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KEZ42904.1 - 4.6e-20 71.8 0.0 6e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEZ42904.1 - 4.5e-18 65.4 0.2 9.2e-17 61.0 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KEZ42904.1 - 2.8e-15 56.2 0.0 3.6e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KEZ42904.1 - 2.9e-06 27.3 0.0 1.4e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Methyltransf_23 PF13489.6 KEZ42905.1 - 2.8e-13 50.0 0.0 4.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ42905.1 - 1e-09 39.0 0.0 3.8e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ42905.1 - 4.3e-09 37.0 0.0 1.2e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ42905.1 - 1.1e-06 28.6 0.0 5.7e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ42905.1 - 2.7e-05 24.7 0.0 6.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ42905.1 - 0.001 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KEZ42905.1 - 0.0073 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KEZ42905.1 - 0.014 14.7 0.0 0.052 12.9 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEZ42905.1 - 0.035 13.8 0.0 0.099 12.4 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase FtsJ PF01728.19 KEZ42905.1 - 0.058 13.5 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.14 KEZ42905.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pep3_Vps18 PF05131.14 KEZ42906.1 - 3e-46 156.9 0.3 9.2e-46 155.3 0.3 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KEZ42906.1 - 8e-13 48.5 8.4 6.1e-09 35.9 0.1 3.7 3 1 0 3 3 3 3 Region in Clathrin and VPS DUF2175 PF09943.9 KEZ42906.1 - 0.0015 18.8 0.2 0.0052 17.0 0.0 2.0 2 0 0 2 2 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 KEZ42906.1 - 0.0026 17.7 0.5 0.0026 17.7 0.5 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEZ42906.1 - 0.0043 16.9 1.3 0.013 15.3 1.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ42906.1 - 0.011 15.7 0.6 0.026 14.5 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KEZ42906.1 - 0.016 14.9 2.0 0.016 14.9 2.0 2.1 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KEZ42906.1 - 0.019 14.6 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KEZ42906.1 - 0.048 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEZ42906.1 - 0.059 13.7 0.8 0.15 12.4 0.8 1.7 1 0 0 1 1 1 0 Ring finger domain ANAPC3 PF12895.7 KEZ42906.1 - 0.067 13.4 0.7 1.4 9.2 0.0 3.3 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3H2C3 PF17122.5 KEZ42906.1 - 0.3 11.2 6.0 0.056 13.5 2.0 1.8 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4 PF00097.25 KEZ42906.1 - 3.1 7.8 4.1 0.94 9.4 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_C PF00137.21 KEZ42907.1 - 1.8e-27 95.4 26.6 3.1e-20 72.3 12.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SH PF01445.17 KEZ42907.1 - 0.096 12.7 0.5 3.2 7.8 0.7 2.4 2 0 0 2 2 2 0 Viral small hydrophobic protein ECF_trnsprt PF12822.7 KEZ42907.1 - 0.64 10.1 17.8 0.043 13.9 10.1 2.0 1 1 1 2 2 2 0 ECF transporter, substrate-specific component TCR_zetazeta PF11628.8 KEZ42907.1 - 0.65 9.7 3.1 21 4.9 0.1 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Asp PF00026.23 KEZ42908.1 - 3.3e-74 250.1 0.1 4.2e-74 249.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ42908.1 - 4.7e-16 59.5 2.0 2.9e-15 57.0 1.4 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEZ42908.1 - 1.3e-07 32.1 0.8 0.0051 17.4 0.1 3.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KEZ42908.1 - 0.00015 22.2 0.1 0.41 11.2 0.0 3.4 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KEZ42908.1 - 0.00021 21.1 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Pkinase PF00069.25 KEZ42909.1 - 6.8e-69 232.2 0.0 1.5e-68 231.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42909.1 - 3.3e-48 164.2 0.0 5.8e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KEZ42909.1 - 7e-28 96.9 0.0 1.3e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KEZ42909.1 - 4.4e-18 65.1 0.2 2.2e-17 62.9 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEZ42909.1 - 1.6e-15 57.3 0.1 3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KEZ42909.1 - 2.5e-14 53.7 0.1 4.2e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KEZ42909.1 - 9.9e-07 28.3 0.0 0.00058 19.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KEZ42909.1 - 0.00097 18.0 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Relaxase PF03432.14 KEZ42909.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain SAM_4 PF18017.1 KEZ42909.1 - 0.018 15.0 0.4 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) GRP PF07172.11 KEZ42909.1 - 0.087 13.5 1.3 0.33 11.7 0.3 2.1 2 0 0 2 2 2 0 Glycine rich protein family SAM_PNT PF02198.16 KEZ42909.1 - 0.17 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PDT PF00800.18 KEZ42910.1 - 8.3e-62 208.2 0.0 1.2e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KEZ42910.1 - 0.0001 22.0 0.0 0.00059 19.6 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 KEZ42910.1 - 0.13 12.9 0.0 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 ACT domain DUF2396 PF09654.10 KEZ42910.1 - 0.15 12.1 0.0 1.5 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) Sulfotransfer_3 PF13469.6 KEZ42911.1 - 6.6e-05 23.4 0.1 0.0006 20.3 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase family Mhr1 PF12829.7 KEZ42912.1 - 6.8e-32 109.4 0.1 1.1e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3437 PF11919.8 KEZ42912.1 - 0.31 11.0 2.3 0.62 10.0 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3437) Ribosomal_S13 PF00416.22 KEZ42914.1 - 2.2e-55 186.5 2.4 2.6e-55 186.3 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PDEase_I PF00233.19 KEZ42915.1 - 3.8e-64 216.7 0.0 6.3e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.29 KEZ42916.1 - 1.6e-68 231.0 0.0 1.4e-66 224.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ42916.1 - 2e-09 37.5 0.1 0.012 15.3 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KEZ42916.1 - 1.4e-07 32.1 0.0 3.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 DUSP domain Peptidase_S10 PF00450.22 KEZ42917.1 - 4.1e-129 431.6 1.8 4.9e-129 431.4 1.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KEZ42917.1 - 4.5e-13 49.8 1.2 5.9e-12 46.2 1.2 2.3 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide NUDIX_2 PF13869.6 KEZ42918.1 - 3.4e-79 264.8 0.0 4e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.17 KEZ42919.1 - 6e-36 123.1 0.0 7.6e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 KEZ42920.1 - 1.3e-15 57.1 1.0 2.1e-15 56.5 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain Peptidase_M16_M PF16187.5 KEZ42921.1 - 4.7e-97 324.6 0.4 1e-96 323.6 0.4 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KEZ42921.1 - 6.3e-33 113.9 0.3 2e-32 112.3 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEZ42921.1 - 7.6e-30 104.3 0.0 8.5e-17 61.7 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Dabb PF07876.12 KEZ42921.1 - 2.4e-22 79.4 0.0 8.2e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain MPP6 PF10175.9 KEZ42922.1 - 1.2e-09 38.8 8.8 1e-06 29.3 8.7 2.6 1 1 0 1 1 1 1 M-phase phosphoprotein 6 zf-CCHC PF00098.23 KEZ42922.1 - 0.00014 21.8 1.4 0.00023 21.1 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle YL1 PF05764.13 KEZ42922.1 - 0.0022 18.1 7.1 0.0022 18.1 7.1 2.1 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 KEZ42922.1 - 0.042 12.2 8.4 0.065 11.5 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC_4 PF14392.6 KEZ42922.1 - 0.19 11.5 0.3 0.32 10.7 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.12 KEZ42922.1 - 0.46 8.6 13.3 0.59 8.3 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KEZ42922.1 - 2.3 6.7 3.3 2.7 6.4 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Utp14 PF04615.13 KEZ42922.1 - 3.8 6.0 22.0 14 4.1 22.0 1.8 1 1 0 1 1 1 0 Utp14 protein Peroxin-3 PF04882.12 KEZ42922.1 - 4.7 6.1 8.9 7 5.5 8.9 1.3 1 1 0 1 1 1 0 Peroxin-3 RNA_pol_Rpc4 PF05132.14 KEZ42922.1 - 5.5 7.4 11.0 0.49 10.8 4.8 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Pet100 PF09803.9 KEZ42923.1 - 2.5e-16 60.0 0.5 3e-16 59.7 0.5 1.1 1 0 0 1 1 1 1 Pet100 DUF5620 PF18522.1 KEZ42923.1 - 0.18 12.2 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) Transcrip_reg PF01709.20 KEZ42924.1 - 2.7e-54 184.1 0.2 3.1e-54 183.9 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator NHL PF01436.21 KEZ42925.1 - 2.6e-05 24.0 0.3 0.0081 16.2 0.0 3.9 4 0 0 4 4 4 1 NHL repeat GSDH PF07995.11 KEZ42925.1 - 0.00015 21.2 0.9 0.019 14.3 0.1 3.4 4 0 0 4 4 4 1 Glucose / Sorbosone dehydrogenase RCC1_2 PF13540.6 KEZ42925.1 - 1.1 9.1 9.1 3.7 7.5 0.4 4.2 4 1 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat HEAT PF02985.22 KEZ42926.1 - 2.3e-10 39.8 14.7 0.37 11.2 0.0 9.1 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 KEZ42926.1 - 4.6e-10 39.7 5.2 0.27 11.6 0.0 7.7 6 2 2 8 8 8 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KEZ42926.1 - 2.3e-08 34.5 0.0 0.012 16.2 0.0 4.1 3 0 0 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KEZ42926.1 - 0.00024 21.5 13.7 0.5 10.9 0.0 7.6 6 2 1 7 7 7 2 HEAT-like repeat Adaptin_N PF01602.20 KEZ42926.1 - 0.00087 18.0 0.2 1.9 7.0 0.0 4.4 3 1 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 KEZ42926.1 - 0.04 13.5 10.2 18 4.8 0.0 5.9 5 1 1 6 6 6 0 CLASP N terminal UNC45-central PF11701.8 KEZ42926.1 - 0.12 12.3 2.4 0.46 10.4 0.0 3.3 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central RRM_1 PF00076.22 KEZ42927.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PD40 PF07676.12 KEZ42928.1 - 0.066 13.2 5.3 17 5.5 0.1 4.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MoaC PF01967.21 KEZ42929.1 - 2e-54 183.4 3.6 3.8e-54 182.5 3.6 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KEZ42929.1 - 2.2e-36 124.6 0.0 1.4e-35 122.0 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KEZ42929.1 - 2.5e-25 89.8 0.1 5e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KEZ42929.1 - 5e-05 23.6 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3783 PF12646.7 KEZ42929.1 - 0.13 12.2 0.0 0.46 10.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) FYVE PF01363.21 KEZ42930.1 - 2.9e-15 56.2 7.9 4.8e-15 55.5 7.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 KEZ42930.1 - 0.5 10.6 12.8 0.49 10.6 8.5 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger CfAFP PF05264.11 KEZ42930.1 - 3.7 7.5 9.0 7.3 6.6 3.5 2.4 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) ELO PF01151.18 KEZ42931.1 - 1.4e-83 280.3 5.6 1.7e-83 280.0 5.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2275 PF10039.9 KEZ42931.1 - 0.066 13.3 2.8 0.11 12.5 2.3 1.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) GMC_oxred_N PF00732.19 KEZ42932.1 - 4.1e-46 157.7 0.1 6.5e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ42932.1 - 6.6e-27 94.8 0.3 2e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEZ42932.1 - 2.2e-07 30.4 0.2 4.4e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ42932.1 - 5.5e-07 29.0 0.1 3.5e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ42932.1 - 1.8e-06 28.1 0.2 4.9e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEZ42932.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ42932.1 - 2e-05 24.4 3.1 0.00024 20.8 3.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ42932.1 - 0.00039 19.2 0.1 0.00065 18.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 KEZ42932.1 - 0.00053 19.3 0.9 0.017 14.4 0.1 2.5 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 KEZ42932.1 - 0.00077 18.9 0.3 0.0012 18.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ42932.1 - 0.03 13.6 0.1 0.06 12.6 0.1 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ42932.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 KEZ42932.1 - 0.17 11.4 0.6 0.27 10.8 0.6 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VASt PF16016.5 KEZ42933.1 - 9.6e-34 117.0 1.8 1.7e-33 116.2 1.8 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KEZ42933.1 - 1.6e-18 67.3 0.0 3.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KEZ42933.1 - 7.4e-06 26.4 0.1 2.4e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 KEZ42933.1 - 0.0066 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 GRAM domain SIMPL PF04402.14 KEZ42933.1 - 0.089 13.2 0.1 0.56 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF541) HrpF PF06266.12 KEZ42933.1 - 0.2 11.9 1.2 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 HrpF protein DUF2428 PF10350.9 KEZ42934.1 - 1.3e-54 185.4 0.1 2.3e-54 184.5 0.1 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KEZ42934.1 - 5.9e-08 32.3 6.9 0.4 11.1 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KEZ42934.1 - 5.7e-05 23.5 8.3 1.5 9.4 0.0 6.0 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 KEZ42934.1 - 0.00073 19.9 4.4 3.5 8.1 0.1 4.9 4 0 0 4 4 4 2 HEAT repeats NinB PF05772.12 KEZ42934.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 NinB protein Ribosomal_L1 PF00687.21 KEZ42935.1 - 3.8e-46 157.4 0.7 4.4e-46 157.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 KEZ42935.1 - 0.088 11.5 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DUF948 PF06103.11 KEZ42935.1 - 0.091 13.0 0.2 0.24 11.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PAN_1 PF00024.26 KEZ42936.1 - 1.6e-06 28.0 0.0 3.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KEZ42936.1 - 0.0022 17.9 0.3 0.0039 17.1 0.3 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KEZ42936.1 - 0.039 13.8 0.4 0.081 12.7 0.4 1.5 1 0 0 1 1 1 0 PAN-like domain Glyco_transf_22 PF03901.17 KEZ42937.1 - 1.9e-59 202.0 23.2 2.3e-59 201.7 23.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.19 KEZ42938.1 - 3.3e-29 100.7 0.2 6.9e-29 99.7 0.2 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KEZ42938.1 - 1.7e-20 73.0 0.2 4.5e-20 71.6 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Arf PF00025.21 KEZ42939.1 - 1.3e-59 200.6 0.2 4.4e-58 195.6 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEZ42939.1 - 7.3e-10 39.1 0.1 1.1e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KEZ42939.1 - 5.5e-08 32.4 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 KEZ42939.1 - 1.4e-07 31.3 0.0 1.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEZ42939.1 - 1.8e-06 27.5 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEZ42939.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 KEZ42939.1 - 0.0016 17.5 0.3 0.0023 16.9 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KEZ42939.1 - 0.004 16.7 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KEZ42939.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TRP PF06011.12 KEZ42940.1 - 4.7e-15 55.2 20.8 3.4e-14 52.4 20.7 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Glyco_hydro_16 PF00722.21 KEZ42942.1 - 2e-12 46.9 0.0 4.2e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KEZ42943.1 - 9.8e-16 57.6 2.2 1.6e-15 56.9 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KEZ42943.1 - 6.5e-08 32.7 12.7 1.1e-05 25.6 5.8 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KEZ42943.1 - 0.00068 20.0 14.6 0.039 14.4 5.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ42943.1 - 0.011 16.6 15.6 0.27 12.2 4.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KEZ42943.1 - 0.016 15.9 0.6 0.8 10.4 0.2 2.7 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KEZ42943.1 - 0.44 10.9 3.7 1.4 9.3 3.7 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding G_path_suppress PF15991.5 KEZ42943.1 - 0.7 10.0 3.2 1.3 9.1 3.2 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor Zn-ribbon_8 PF09723.10 KEZ42943.1 - 1.3 9.2 4.1 4.1 7.6 4.1 1.9 1 0 0 1 1 1 0 Zinc ribbon domain RasGEF PF00617.19 KEZ42944.1 - 1.2e-61 208.0 0.1 2.4e-61 207.0 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEZ42944.1 - 4.4e-30 104.0 0.3 1e-29 102.8 0.3 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KEZ42944.1 - 2.7e-16 58.9 0.1 5.4e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ42944.1 - 3.4e-14 52.4 0.2 7.9e-14 51.2 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KEZ42944.1 - 4.3e-14 51.9 0.1 9e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KEZ42944.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 WW domain DUF1944 PF09175.10 KEZ42944.1 - 0.079 12.8 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1944) RHH_1 PF01402.21 KEZ42944.1 - 2.1 8.4 4.6 0.96 9.5 1.3 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family SCA7 PF08313.12 KEZ42945.1 - 3.6e-31 106.9 0.2 8.6e-31 105.6 0.2 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf_C2HC_14 PF18574.1 KEZ42945.1 - 0.67 9.8 3.9 1.2 9.0 3.9 1.3 1 0 0 1 1 1 0 C2HC Zing finger domain DUF3245 PF11595.8 KEZ42945.1 - 1.8 9.0 25.7 0.38 11.2 19.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) Acyltransferase PF01553.21 KEZ42946.1 - 2.8e-12 46.4 0.0 4.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase zf-RING_UBOX PF13445.6 KEZ42947.1 - 6e-09 35.8 9.6 3.4e-06 27.0 3.8 2.9 2 0 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 KEZ42947.1 - 1.5e-08 34.6 0.1 2.2e-07 30.9 0.0 2.8 3 1 0 3 3 3 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 KEZ42947.1 - 1.5e-06 27.8 1.2 1.5e-06 27.8 1.2 2.8 2 1 1 3 3 3 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KEZ42947.1 - 6.6e-06 26.4 17.0 0.00014 22.2 6.7 2.6 3 0 0 3 3 2 2 Ring finger domain zf-C3HC4 PF00097.25 KEZ42947.1 - 2e-05 24.3 14.3 0.00027 20.7 6.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ42947.1 - 6.3e-05 22.9 4.5 6.3e-05 22.9 4.5 2.9 2 2 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KEZ42947.1 - 0.00025 21.1 14.4 0.0083 16.3 7.0 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KEZ42947.1 - 0.00027 20.7 15.4 0.0008 19.2 3.0 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KEZ42947.1 - 0.33 11.1 11.6 1.1 9.5 6.5 2.8 2 1 1 3 3 3 0 FYVE zinc finger DUF4407 PF14362.6 KEZ42947.1 - 0.76 9.1 5.7 1.2 8.4 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BSP_II PF05432.11 KEZ42947.1 - 2.3 7.8 8.1 0.079 12.7 2.2 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Rad50_zn_hook PF04423.14 KEZ42947.1 - 4 7.3 6.3 10 6.1 0.0 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Pkinase PF00069.25 KEZ42948.1 - 2.7e-76 256.4 0.0 3.2e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ42948.1 - 2.9e-37 128.4 0.0 4e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEZ42948.1 - 0.00042 19.4 0.0 0.0039 16.2 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEZ42948.1 - 0.032 13.6 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEZ42948.1 - 0.082 12.2 0.1 0.29 10.4 0.0 1.9 1 1 0 2 2 2 0 Kinase-like APH PF01636.23 KEZ42948.1 - 0.097 12.6 1.8 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Septin PF00735.18 KEZ42949.1 - 1.8e-10 40.6 1.4 4.8e-07 29.4 0.0 3.0 2 1 1 3 3 3 2 Septin AAA_16 PF13191.6 KEZ42949.1 - 0.0029 18.0 0.3 0.01 16.2 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ42949.1 - 0.0065 16.5 0.0 0.037 14.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEZ42949.1 - 0.017 14.7 0.0 1.3 8.5 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 KEZ42949.1 - 0.07 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KEZ42949.1 - 0.089 11.9 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KEZ42949.1 - 0.14 11.5 0.9 4.1 6.7 0.4 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KEZ42949.1 - 0.2 10.8 0.6 0.31 10.2 0.6 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 KEZ42949.1 - 1.2 9.5 2.9 0.92 9.8 0.6 1.8 2 0 0 2 2 2 0 AAA domain PAP_central PF04928.17 KEZ42950.1 - 9.3e-107 355.6 0.0 1.2e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KEZ42950.1 - 1.4e-58 197.4 0.0 3.3e-58 196.1 0.0 1.7 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KEZ42950.1 - 1.2e-07 31.9 0.0 3.4e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KEZ42950.1 - 0.054 13.3 0.2 0.23 11.2 0.2 2.0 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain Tubulin_3 PF14881.6 KEZ42951.1 - 4.4e-51 173.1 0.0 1.7e-50 171.3 0.0 1.9 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KEZ42951.1 - 3e-38 130.7 0.0 5.6e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KEZ42951.1 - 4.2e-06 27.1 0.0 0.0012 19.1 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Aminotran_3 PF00202.21 KEZ42952.1 - 2.5e-80 270.1 0.0 3.1e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEZ42952.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ERG2_Sigma1R PF04622.12 KEZ42952.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein Forkhead PF00250.18 KEZ42953.1 - 1.7e-34 117.9 0.2 3.1e-34 117.1 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KEZ42953.1 - 4.3e-10 39.8 0.0 8.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KEZ42953.1 - 0.00043 20.6 0.0 0.0011 19.2 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KEZ42953.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 FHA domain CLU PF13236.6 KEZ42954.1 - 2.7e-74 249.8 0.0 4.7e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KEZ42954.1 - 7.5e-55 185.7 0.8 2.2e-54 184.2 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KEZ42954.1 - 5.7e-27 93.8 7.2 9.7e-12 45.0 0.4 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ42954.1 - 1.6e-23 81.8 4.2 2.4e-06 27.2 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat CLU_N PF15044.6 KEZ42954.1 - 6.5e-23 80.9 0.5 1.6e-22 79.6 0.5 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 KEZ42954.1 - 0.00012 22.0 3.2 0.06 13.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ42954.1 - 0.00056 19.8 3.3 0.92 9.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 KEZ42954.1 - 0.037 14.1 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF727) TPR_9 PF13371.6 KEZ42954.1 - 0.047 13.9 0.1 2.7 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ferric_reduct PF01794.19 KEZ42955.1 - 5.2e-24 84.7 13.3 1.1e-23 83.7 12.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEZ42955.1 - 2.5e-17 63.4 0.0 8.4e-10 39.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEZ42955.1 - 2.9e-14 53.0 0.0 7.7e-13 48.5 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain SPOUT_MTase PF02590.17 KEZ42955.1 - 0.028 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Yippee-Mis18 PF03226.14 KEZ42956.1 - 1.2e-16 60.9 0.7 1.3e-16 60.7 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KEZ42956.1 - 0.00067 19.9 0.8 0.00096 19.4 0.8 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 KEZ42956.1 - 0.016 15.5 1.2 0.055 13.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RNA_POL_M_15KD PF02150.16 KEZ42956.1 - 0.051 13.5 1.9 7.4 6.5 0.2 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_ribbon_SprT PF17283.2 KEZ42956.1 - 0.08 12.9 2.1 9 6.3 0.4 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain EamA PF00892.20 KEZ42957.1 - 1e-08 35.4 24.3 0.00043 20.4 5.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KEZ42957.1 - 2.3e-08 33.6 1.6 4.2e-08 32.7 1.6 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KEZ42957.1 - 0.00026 20.4 1.2 0.00026 20.4 1.2 2.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF423 PF04241.15 KEZ42957.1 - 0.092 13.0 5.9 4.5 7.6 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF423) PDR_assoc PF08370.11 KEZ42957.1 - 0.097 12.4 5.4 6.7 6.5 0.3 3.2 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF2985 PF11204.8 KEZ42958.1 - 4.2e-40 135.8 1.8 4.2e-40 135.8 1.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) SIT PF15330.6 KEZ42958.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Phage_holin_3_6 PF07332.11 KEZ42958.1 - 6.5 6.8 8.5 0.51 10.4 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ADH_N PF08240.12 KEZ42959.1 - 1.5e-29 102.1 0.5 1.5e-29 102.1 0.5 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ42959.1 - 5.8e-15 55.4 0.0 9.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ42959.1 - 4.8e-06 26.2 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KEZ42959.1 - 0.002 18.0 0.1 0.0041 17.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 KEZ42959.1 - 0.0032 18.5 0.0 0.0054 17.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C2H2 PF00096.26 KEZ42960.1 - 4.3e-06 26.9 11.7 0.042 14.3 0.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ42960.1 - 0.067 14.1 9.6 0.65 11.0 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 KEZ42960.1 - 0.12 12.7 4.8 0.26 11.6 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KEZ42960.1 - 0.63 10.6 9.4 7.4 7.2 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Peptidase_C2 PF00648.21 KEZ42961.1 - 4.5e-22 78.4 0.0 8.2e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 KEZ42961.1 - 8.6e-13 48.8 0.0 2.1e-05 24.8 0.0 3.4 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.18 KEZ42961.1 - 0.063 13.4 0.5 0.099 12.7 0.5 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 KEZ42962.1 - 3.1e-55 184.1 0.2 3.7e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 KEZ42962.1 - 1.4 9.1 4.1 3.8 7.7 0.4 2.6 2 1 0 2 2 2 0 Pre-toxin domain with VENN motif SAM_2 PF07647.17 KEZ42963.1 - 6.1e-09 35.9 0.1 1.3e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEZ42963.1 - 0.0002 21.7 0.2 0.00045 20.6 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KEZ42963.1 - 0.032 14.3 0.2 0.092 12.9 0.2 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 KEZ42963.1 - 0.12 12.7 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) TPR_19 PF14559.6 KEZ42964.1 - 8.7e-08 32.6 26.3 0.078 13.5 0.9 9.3 8 3 3 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ42964.1 - 2.8e-07 30.1 4.7 0.32 10.7 0.0 6.4 7 1 1 8 8 8 2 TPR repeat TPR_1 PF00515.28 KEZ42964.1 - 4.1e-07 29.5 18.6 0.11 12.3 0.1 8.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ42964.1 - 1.8e-06 27.7 9.4 0.14 12.4 0.1 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ42964.1 - 2.1e-06 28.3 30.9 0.0052 17.4 0.7 8.8 8 2 2 10 10 9 4 Tetratricopeptide repeat TPR_20 PF14561.6 KEZ42964.1 - 3e-06 27.5 15.5 0.13 12.6 1.0 7.4 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ42964.1 - 3.9e-06 27.2 23.2 0.14 13.0 0.1 9.2 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ42964.1 - 0.00014 21.9 4.2 0.37 11.3 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ42964.1 - 0.00064 19.6 38.3 0.17 12.0 0.1 11.4 15 0 0 15 15 12 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ42964.1 - 0.008 16.5 24.0 0.88 9.9 2.8 8.2 7 3 2 9 9 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEZ42964.1 - 0.048 13.7 0.3 3.2 7.9 0.0 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KEZ42964.1 - 0.055 13.9 1.4 34 4.9 0.0 3.7 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation TPR_7 PF13176.6 KEZ42964.1 - 0.095 12.8 13.1 0.93 9.7 0.1 6.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ42964.1 - 0.71 10.1 11.9 0.19 11.9 1.2 4.6 3 2 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 KEZ42966.1 - 2.1e-46 157.8 3.7 8e-23 81.5 0.0 3.4 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KEZ42966.1 - 9e-21 73.7 7.5 9e-21 73.7 7.5 3.7 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.6 KEZ42966.1 - 9.4e-17 61.8 2.1 0.00016 21.6 0.0 4.6 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ42966.1 - 3.1e-09 36.6 4.7 0.015 14.7 0.0 4.5 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KEZ42966.1 - 4.9e-07 30.3 0.0 0.023 15.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KEZ42966.1 - 3.9e-06 26.9 1.5 0.016 15.3 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KEZ42966.1 - 5.3e-06 26.1 0.2 0.049 13.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ42966.1 - 9.8e-06 26.2 18.0 0.029 14.9 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.6 KEZ42966.1 - 1.7e-05 25.0 0.0 0.15 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEZ42966.1 - 1.7e-05 25.3 0.2 0.021 15.2 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ42966.1 - 2.3e-05 24.4 1.0 0.023 14.6 0.1 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 KEZ42966.1 - 3.4e-05 24.1 0.0 0.18 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEZ42966.1 - 5.5e-05 23.0 0.8 0.014 15.2 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 KEZ42966.1 - 6.9e-05 22.7 0.5 0.91 9.2 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KEZ42966.1 - 0.00035 21.0 0.0 0.65 10.4 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEZ42966.1 - 0.00037 20.8 1.2 0.25 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KEZ42966.1 - 0.00043 20.1 13.8 0.28 10.8 0.1 5.1 5 1 0 6 6 6 2 AAA ATPase domain AAA_14 PF13173.6 KEZ42966.1 - 0.0011 19.0 0.0 3 7.9 0.0 3.2 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KEZ42966.1 - 0.0025 16.9 2.5 0.56 9.1 0.0 2.6 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 KEZ42966.1 - 0.0057 16.3 0.6 1.6 8.3 0.5 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KEZ42966.1 - 0.0058 16.2 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 KEZ42966.1 - 0.0087 16.0 0.5 4.6 7.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 KEZ42966.1 - 0.0098 15.8 0.1 1.4 8.8 0.0 2.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KEZ42966.1 - 0.011 16.1 0.1 8.2 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 KEZ42966.1 - 0.018 15.3 0.1 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KEZ42966.1 - 0.02 14.8 1.2 3.3 7.6 0.0 3.2 2 1 0 3 3 3 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 KEZ42966.1 - 0.025 14.3 0.0 0.43 10.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KEZ42966.1 - 0.029 13.5 0.0 8.2 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 KEZ42966.1 - 0.04 13.9 0.4 7 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MobB PF03205.14 KEZ42966.1 - 0.046 13.6 0.3 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 KEZ42966.1 - 0.069 13.2 10.5 0.97 9.5 0.1 4.3 4 1 0 4 4 4 0 Dynamin family Mg_chelatase PF01078.21 KEZ42966.1 - 0.08 12.3 1.8 21 4.4 0.1 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 KEZ42966.1 - 0.11 12.1 2.2 4.4 6.9 0.1 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 KEZ42966.1 - 0.12 12.8 8.2 17 5.8 0.1 4.2 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 KEZ42966.1 - 0.16 11.7 0.3 24 4.6 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_27 PF13514.6 KEZ42966.1 - 1.4 8.4 10.7 2.4 7.7 0.0 3.5 6 0 0 6 6 2 0 AAA domain RsbRD_N PF14361.6 KEZ42966.1 - 7.5 7.3 7.3 3.7 8.3 0.1 3.4 3 1 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Tubulin PF00091.25 KEZ42967.1 - 1.9e-64 217.5 0.0 8.8e-64 215.3 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEZ42967.1 - 2.1e-42 144.2 0.0 3.5e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KEZ42967.1 - 0.0037 17.0 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KEZ42967.1 - 0.0056 15.9 0.0 0.023 13.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.9 KEZ42967.1 - 0.0096 16.2 0.0 0.047 14.0 0.0 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Ribosomal_L6 PF00347.23 KEZ42968.1 - 8.7e-21 74.4 0.3 4.6e-10 40.0 0.0 3.1 2 1 1 3 3 3 2 Ribosomal protein L6 Aha1_N PF09229.11 KEZ42970.1 - 7.4e-41 139.6 0.7 1.1e-40 139.0 0.7 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KEZ42970.1 - 1.4e-18 67.3 0.5 2.6e-18 66.5 0.5 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DHHC PF01529.20 KEZ42971.1 - 2.3e-30 105.4 3.7 2.3e-30 105.4 3.7 2.5 3 0 0 3 3 3 1 DHHC palmitoyltransferase Rap1_C PF11626.8 KEZ42972.1 - 4.7e-24 84.3 2.8 6.1e-22 77.5 0.1 3.5 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KEZ42972.1 - 2.8e-19 69.0 6.4 8.4e-13 48.3 0.5 2.6 2 0 0 2 2 2 2 Rap1 Myb domain BRCT_2 PF16589.5 KEZ42972.1 - 6.5e-12 45.7 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KEZ42972.1 - 0.00011 22.8 8.5 0.03 14.9 0.6 3.4 3 0 0 3 3 3 2 Rap1, DNA-binding ARID PF01388.21 KEZ42972.1 - 0.00019 22.0 0.0 0.00042 20.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain tRNA-synt_1c PF00749.21 KEZ42972.1 - 0.039 12.8 5.0 0.16 10.9 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain BRCT PF00533.26 KEZ42972.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CN_hydrolase PF00795.22 KEZ42973.1 - 8e-30 104.0 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase p450 PF00067.22 KEZ42974.1 - 7.4e-40 137.1 0.0 4.5e-38 131.2 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 HLH PF00010.26 KEZ42975.1 - 2.6e-15 56.1 0.0 5.7e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 KEZ42975.1 - 1.3 9.0 28.4 0.068 13.2 22.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_M24 PF00557.24 KEZ42976.1 - 2.1e-45 155.0 0.0 2.9e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEZ42976.1 - 2.2e-32 111.4 0.0 4e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 KEZ42977.1 - 3.7e-40 137.1 0.0 9.7e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KEZ42977.1 - 1.7e-19 69.7 0.2 3.4e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger HNH PF01844.23 KEZ42977.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease Siva PF05458.12 KEZ42977.1 - 1.3 8.7 4.0 0.33 10.6 0.2 2.0 3 0 0 3 3 3 0 Cd27 binding protein (Siva) bZIP_1 PF00170.21 KEZ42978.1 - 0.007 16.4 2.3 0.018 15.1 2.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF5595 PF18077.1 KEZ42978.1 - 5 7.3 5.3 0.62 10.2 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) APG12 PF04110.13 KEZ42979.1 - 2.2e-27 95.3 0.0 3.1e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KEZ42979.1 - 0.0029 17.8 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 KEZ42980.1 - 1.8e-104 348.8 0.3 2.1e-104 348.5 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KEZ42980.1 - 4.2e-09 36.2 0.1 4.2e-09 36.2 0.1 1.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KEZ42980.1 - 0.022 13.8 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) UQ_con PF00179.26 KEZ42981.1 - 3.1e-34 117.6 0.0 5.1e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HNH_2 PF13391.6 KEZ42981.1 - 0.014 15.5 0.1 0.044 13.9 0.1 1.9 2 0 0 2 2 2 0 HNH endonuclease CorA PF01544.18 KEZ42982.1 - 3.4e-05 23.3 3.3 6.9e-05 22.3 1.3 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein MFS_5 PF05631.14 KEZ42983.1 - 5.3e-68 229.5 2.7 6.9e-68 229.1 2.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KEZ42983.1 - 7.7e-23 81.0 25.6 7.7e-23 81.0 25.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily SIR2 PF02146.17 KEZ42984.1 - 1e-33 116.8 0.0 3.1e-33 115.2 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Peripla_BP_4 PF13407.6 KEZ42984.1 - 0.0058 16.2 0.0 0.0084 15.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain PhnA_Zn_Ribbon PF08274.12 KEZ42984.1 - 0.053 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Soyouz_module PF14313.6 KEZ42984.1 - 0.077 12.8 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Glyco_hydro_16 PF00722.21 KEZ42985.1 - 1.7e-42 144.9 1.2 3.2e-42 144.0 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MR_MLE_C PF13378.6 KEZ42986.1 - 1e-57 195.2 0.1 2.3e-57 194.1 0.0 1.5 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KEZ42986.1 - 0.0011 19.2 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KEZ42986.1 - 0.0012 18.0 0.0 0.0032 16.7 0.0 1.6 1 1 1 2 2 2 1 Methylaspartate ammonia-lyase C-terminus AAA_lid_9 PF17871.1 KEZ42986.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain Pectate_lyase_3 PF12708.7 KEZ42987.1 - 6.4e-94 313.8 5.7 1.4e-79 266.9 1.6 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KEZ42987.1 - 1.8e-07 30.7 1.4 0.0043 16.7 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase LysM PF01476.20 KEZ42987.1 - 0.011 15.7 0.0 0.41 10.7 0.0 2.9 3 0 0 3 3 3 0 LysM domain Glyco_hydro_18 PF00704.28 KEZ42988.1 - 9.6e-61 206.2 0.1 1.4e-60 205.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEZ42988.1 - 1.6e-09 38.1 6.1 1.6e-09 38.1 6.1 4.4 5 0 0 5 5 5 1 Chitin recognition protein Rad10 PF03834.14 KEZ42989.1 - 3.8e-46 155.8 0.1 5.2e-46 155.4 0.1 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KEZ42989.1 - 0.00094 19.7 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain SART-1 PF03343.13 KEZ42989.1 - 0.055 12.0 0.5 0.068 11.7 0.5 1.1 1 0 0 1 1 1 0 SART-1 family DUF4712 PF15830.5 KEZ42989.1 - 0.19 11.4 0.8 0.39 10.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Glyco_hydro_47 PF01532.20 KEZ42990.1 - 3.1e-134 448.3 0.0 3.6e-134 448.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 VIT1 PF01988.19 KEZ42991.1 - 2.6e-63 213.8 2.5 3.1e-63 213.5 2.5 1.1 1 0 0 1 1 1 1 VIT family Lactamase_B_2 PF12706.7 KEZ42992.1 - 6.3e-33 114.0 0.0 3.4e-31 108.3 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEZ42992.1 - 1.9e-11 44.1 0.0 5.4e-11 42.6 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KEZ42992.1 - 4.8e-05 23.5 0.3 0.0012 18.9 0.1 2.6 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Ndc80_HEC PF03801.13 KEZ42993.1 - 2.5e-61 205.8 0.2 4.6e-61 204.9 0.2 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DHR10 PF18595.1 KEZ42993.1 - 2.3e-05 24.4 15.3 2.3e-05 24.4 15.3 3.8 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain Filament PF00038.21 KEZ42993.1 - 4e-05 23.3 44.6 0.021 14.4 16.1 3.5 3 1 1 4 4 4 2 Intermediate filament protein Spc7 PF08317.11 KEZ42993.1 - 0.00033 19.6 16.1 0.00033 19.6 16.1 3.3 3 0 0 3 3 3 2 Spc7 kinetochore protein DUF5595 PF18077.1 KEZ42993.1 - 0.0021 18.1 4.2 0.0021 18.1 4.2 5.2 5 2 1 6 6 5 1 Domain of unknown function (DUF5595) APG6_N PF17675.1 KEZ42993.1 - 0.0025 18.4 49.4 0.15 12.6 1.5 4.6 3 1 0 3 3 3 2 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KEZ42993.1 - 0.011 15.8 15.5 0.011 15.8 15.5 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KEZ42993.1 - 0.016 15.3 1.0 0.016 15.3 1.0 4.9 3 2 2 5 5 4 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KEZ42993.1 - 0.02 15.4 8.5 0.02 15.4 8.5 4.0 2 2 1 3 3 3 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KEZ42993.1 - 0.064 13.7 12.7 8.9 6.9 0.8 4.8 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 KEZ42993.1 - 0.075 13.4 38.5 0.09 13.2 16.3 4.0 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 KEZ42993.1 - 0.57 10.3 32.1 0.94 9.6 2.9 4.4 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 KEZ42993.1 - 0.59 9.9 31.9 4.2 7.2 3.6 4.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 KEZ42993.1 - 1.2 8.5 45.1 1.7 8.1 14.9 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KEZ42993.1 - 1.9 7.8 27.6 1.1 8.6 9.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) HemX PF04375.14 KEZ42993.1 - 2 7.7 19.0 0.033 13.5 6.0 2.8 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF948 PF06103.11 KEZ42993.1 - 2.1 8.7 13.7 1.5 9.2 1.5 4.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) GAS PF13851.6 KEZ42993.1 - 2.5 7.4 44.2 0.021 14.2 14.1 3.6 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Ntox28 PF15605.6 KEZ42993.1 - 2.6 8.3 17.2 1.2 9.5 1.3 4.6 3 2 2 6 6 6 0 Bacterial toxin 28 Prominin PF05478.11 KEZ42993.1 - 3.3 5.5 17.8 0.81 7.6 4.8 2.4 2 0 0 2 2 2 0 Prominin HALZ PF02183.18 KEZ42993.1 - 3.8 7.8 14.0 1.2 9.4 1.2 4.4 3 1 1 4 4 4 0 Homeobox associated leucine zipper FlxA PF14282.6 KEZ42993.1 - 3.9 7.5 26.5 7 6.7 1.8 4.5 3 1 1 4 4 4 0 FlxA-like protein FliD_C PF07195.12 KEZ42993.1 - 7.6 5.9 19.2 16 4.8 8.7 3.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ABC_tran_CTD PF16326.5 KEZ42993.1 - 8.2 6.8 45.8 0.21 11.9 4.6 5.3 3 2 2 5 5 5 0 ABC transporter C-terminal domain STAT_alpha PF01017.20 KEZ42993.1 - 8.3 6.3 23.5 0.069 13.0 4.6 3.1 2 1 1 3 3 3 0 STAT protein, all-alpha domain DUF4510 PF14971.6 KEZ42993.1 - 8.9 6.6 9.0 0.58 10.5 1.3 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4510) Pex14_N PF04695.13 KEZ42994.1 - 6.5e-38 130.9 6.6 6.5e-38 130.9 6.6 3.2 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.9 KEZ42994.1 - 0.00038 20.9 3.5 0.00038 20.9 3.5 2.2 2 0 0 2 2 2 1 Zinc finger-containing protein UPF0242 PF06785.11 KEZ42994.1 - 0.0015 18.7 2.5 0.0022 18.1 2.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus CR6_interact PF10147.9 KEZ42994.1 - 0.0023 17.7 0.6 0.0038 17.0 0.4 1.4 1 1 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Prominin PF05478.11 KEZ42994.1 - 0.0026 15.8 1.2 0.0033 15.5 1.2 1.1 1 0 0 1 1 1 1 Prominin HLH PF00010.26 KEZ42994.1 - 0.0081 16.1 0.0 1.6 8.8 0.0 3.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spc7 PF08317.11 KEZ42994.1 - 0.077 11.9 7.0 0.13 11.2 7.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1043 PF06295.12 KEZ42994.1 - 0.09 12.8 4.9 0.08 12.9 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) 5_nucleotid PF05761.14 KEZ42994.1 - 0.12 11.2 3.3 0.16 10.8 3.3 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF3584 PF12128.8 KEZ42994.1 - 0.17 9.3 10.8 0.22 9.0 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SKA2 PF16740.5 KEZ42994.1 - 0.25 11.1 7.5 0.83 9.5 1.6 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 FUSC PF04632.12 KEZ42994.1 - 0.25 9.8 3.7 0.38 9.2 3.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KEZ42994.1 - 0.25 11.4 4.9 0.28 11.2 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KEZ42994.1 - 0.27 11.9 8.1 0.32 11.6 4.3 2.8 1 1 2 3 3 3 0 SlyX Baculo_PEP_C PF04513.12 KEZ42994.1 - 0.29 11.2 8.4 1.9 8.5 0.9 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF148 PF02520.17 KEZ42994.1 - 0.34 11.0 4.9 4.8 7.3 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 Atg14 PF10186.9 KEZ42994.1 - 0.4 9.7 4.9 0.6 9.1 4.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KEZ42994.1 - 0.49 9.6 3.2 0.77 8.9 3.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.6 KEZ42994.1 - 0.67 8.5 6.5 0.87 8.1 6.5 1.1 1 0 0 1 1 1 0 AAA domain FlgN PF05130.12 KEZ42994.1 - 0.84 10.1 9.9 1.5 9.3 9.9 1.3 1 0 0 1 1 1 0 FlgN protein Fez1 PF06818.15 KEZ42994.1 - 0.87 10.0 8.0 1.3 9.4 8.0 1.3 1 0 0 1 1 1 0 Fez1 IFT57 PF10498.9 KEZ42994.1 - 1.1 8.1 7.9 1.7 7.6 7.9 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SYCE1 PF15233.6 KEZ42994.1 - 1.5 8.8 10.0 2.5 8.1 10.0 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF16 PF01519.16 KEZ42994.1 - 2 9.0 6.1 2.3 8.8 1.3 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 DUF572 PF04502.13 KEZ42994.1 - 2.9 7.4 9.0 4.2 6.9 9.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Golgin_A5 PF09787.9 KEZ42994.1 - 3 7.2 13.0 3.6 7.0 12.2 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 Uso1_p115_C PF04871.13 KEZ42994.1 - 4.8 7.6 13.6 67 3.9 13.7 2.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region V_ATPase_I PF01496.19 KEZ42994.1 - 5.7 4.7 4.8 7.5 4.3 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 KEZ42994.1 - 9 5.0 8.7 33 3.2 8.7 1.8 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain XhlA PF10779.9 KEZ42994.1 - 9.9 6.5 7.6 7.5 6.8 2.8 2.5 1 1 1 2 2 2 0 Haemolysin XhlA Abhydrolase_3 PF07859.13 KEZ42995.1 - 1.7e-45 155.5 0.0 3.9e-45 154.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEZ42995.1 - 4.1e-05 22.6 0.0 0.00022 20.2 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase HMG_CoA_synt_C PF08540.10 KEZ42996.1 - 4.4e-102 341.5 0.1 5.7e-102 341.1 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KEZ42996.1 - 6e-94 312.8 0.2 9.2e-94 312.2 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BCS1_N PF08740.11 KEZ42997.1 - 4.2e-55 186.6 7.3 1.3e-54 185.0 3.5 2.3 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KEZ42997.1 - 9.6e-18 64.9 0.0 7.2e-16 58.8 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ42997.1 - 0.00033 21.1 0.0 0.0014 19.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KEZ42997.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEZ42997.1 - 0.0021 18.1 0.0 0.0073 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEZ42997.1 - 0.0044 16.6 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ42997.1 - 0.0045 17.5 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEZ42997.1 - 0.008 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KEZ42997.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KEZ42997.1 - 0.032 13.6 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KEZ42997.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ42997.1 - 0.11 12.7 0.0 0.86 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEZ42997.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KEZ42997.1 - 0.15 12.5 0.0 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA helicase PT PF04886.12 KEZ42998.1 - 0.00016 21.1 4.0 0.00023 20.6 0.5 3.2 2 0 0 2 2 2 1 PT repeat DUF2798 PF11391.8 KEZ42998.1 - 0.069 13.2 0.9 0.16 12.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) DUF1501 PF07394.12 KEZ42998.1 - 0.15 11.1 0.6 0.25 10.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Homoserine_dh PF00742.19 KEZ42999.1 - 1.5e-52 178.1 0.0 2e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KEZ42999.1 - 9.2e-19 68.2 0.0 1.4e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain RRM_1 PF00076.22 KEZ43000.1 - 3.1e-20 71.8 0.0 1.4e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEX11 PF05648.14 KEZ43001.1 - 5.2e-74 248.5 0.4 5.9e-74 248.3 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RETICULATA-like PF11891.8 KEZ43001.1 - 0.04 13.7 0.0 0.099 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein RETICULATA-related FBPase PF00316.20 KEZ43002.1 - 9.1e-72 240.5 0.2 1.3e-71 240.0 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain bZIP_1 PF00170.21 KEZ43003.1 - 0.00051 20.1 7.5 0.00051 20.1 7.5 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KEZ43003.1 - 0.0011 19.0 7.6 0.0019 18.2 7.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Rcd1 PF04078.13 KEZ43004.1 - 4e-126 419.6 6.0 4.7e-126 419.4 6.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.18 KEZ43004.1 - 0.15 12.2 0.2 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit Pkinase PF00069.25 KEZ43005.1 - 1.8e-60 204.5 0.0 4.3e-60 203.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43005.1 - 1.1e-35 123.2 0.0 2.9e-35 121.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEZ43005.1 - 1.1e-06 27.9 0.0 1.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEZ43005.1 - 6.9e-06 25.6 0.1 9.2e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEZ43005.1 - 3.2e-05 23.4 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ43005.1 - 0.00048 20.1 0.0 0.0035 17.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ43005.1 - 0.01 15.4 0.5 0.078 12.6 0.3 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 KEZ43005.1 - 0.012 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 KEZ43005.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF1604 PF07713.13 KEZ43006.1 - 2.9e-36 123.1 0.3 5.6e-36 122.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KEZ43006.1 - 4.9e-06 26.3 2.0 0.00017 21.4 1.1 2.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KEZ43006.1 - 0.012 15.7 0.1 0.062 13.4 0.0 2.3 2 0 0 2 2 2 0 G-patch domain WD40 PF00400.32 KEZ43007.1 - 2.4e-21 75.6 13.9 1.2e-05 26.0 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ43007.1 - 2.2e-09 37.5 0.4 5.4e-05 23.4 0.0 3.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KEZ43007.1 - 3.6e-06 27.0 2.1 0.032 14.2 0.2 2.5 2 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KEZ43007.1 - 0.083 11.8 1.2 1.7 7.5 0.0 3.0 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein bZIP_1 PF00170.21 KEZ43008.1 - 4.4e-06 26.7 11.7 0.00013 21.9 8.6 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KEZ43008.1 - 7.4e-05 22.8 13.4 0.0001 22.3 10.6 2.2 2 0 0 2 2 2 1 Basic region leucine zipper TTKRSYEDQ PF10212.9 KEZ43008.1 - 0.016 14.3 0.8 0.024 13.7 0.8 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.17 KEZ43008.1 - 9.3 6.8 9.7 0.74 10.4 4.2 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor MARVEL PF01284.23 KEZ43009.1 - 8.4e-13 48.6 19.5 1.2e-12 48.1 19.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain Alkyl_sulf_dimr PF14863.6 KEZ43010.1 - 1.8e-54 183.9 0.0 3.5e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KEZ43010.1 - 2.5e-30 106.0 0.0 5.1e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PX PF00787.24 KEZ43010.1 - 1.5e-24 86.1 0.0 2.6e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 PX domain Alkyl_sulf_C PF14864.6 KEZ43010.1 - 1.3e-18 67.4 0.0 2.8e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 KEZ43010.1 - 6.1e-06 25.9 0.0 3e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Mito_carr PF00153.27 KEZ43011.1 - 7.3e-71 234.2 4.7 1.6e-23 82.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KEZ43011.1 - 0.0042 16.3 1.0 1.5 7.9 0.0 3.1 2 1 0 2 2 2 2 Gammaproteobacterial serine protease SUIM_assoc PF16619.5 KEZ43012.1 - 0.0079 16.2 1.0 2.2 8.4 0.4 2.8 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Zn_clus PF00172.18 KEZ43012.1 - 0.012 15.7 11.3 0.022 14.9 11.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PADR1 PF08063.12 KEZ43012.1 - 1.1 9.1 4.8 2 8.3 4.8 1.3 1 0 0 1 1 1 0 PADR1 (NUC008) domain LSM PF01423.22 KEZ43013.1 - 5.1e-19 67.7 0.1 6.5e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KEZ43013.1 - 0.041 14.4 9.2 0.062 13.9 9.2 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 KEZ43013.1 - 0.073 13.2 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 RimP C-terminal SH3 domain RhlB PF12300.8 KEZ43013.1 - 3.6 7.7 8.4 5.1 7.2 8.4 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB UCH PF00443.29 KEZ43014.1 - 2.6e-47 161.5 0.0 3.6e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ43014.1 - 3.9e-13 49.7 3.8 1.5e-12 47.8 3.8 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KEZ43014.1 - 4.2e-11 42.4 0.1 1e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family TAF4 PF05236.14 KEZ43014.1 - 0.032 14.0 5.4 0.046 13.5 5.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2992 PF11208.8 KEZ43014.1 - 0.06 13.6 4.7 0.11 12.8 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF5320 PF17253.2 KEZ43015.1 - 0.15 13.1 0.0 0.21 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Ax_dynein_light PF10211.9 KEZ43015.1 - 0.18 11.7 5.5 0.23 11.4 5.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Met_gamma_lyase PF06838.11 KEZ43015.1 - 0.19 10.2 0.1 0.24 9.9 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase GAT PF03127.14 KEZ43016.1 - 1.2e-18 67.2 0.4 3e-18 65.9 0.4 1.7 1 0 0 1 1 1 1 GAT domain SIKE PF05769.11 KEZ43016.1 - 0.068 13.1 0.6 0.12 12.3 0.6 1.3 1 0 0 1 1 1 0 SIKE family Zn_clus PF00172.18 KEZ43017.1 - 2.2e-07 30.9 7.2 3.2e-07 30.3 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KEZ43018.1 - 1.6e-15 57.3 0.1 2.2e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43018.1 - 3.3e-14 52.9 0.0 4.6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ43018.1 - 3.7e-13 49.9 0.0 9.1e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ43018.1 - 3.9e-13 49.9 0.0 9.6e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ43018.1 - 1.3e-12 48.3 0.0 3.3e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ43018.1 - 2e-08 33.9 0.0 3.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KEZ43018.1 - 0.00026 21.0 0.0 0.0006 19.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain TPMT PF05724.11 KEZ43018.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KEZ43018.1 - 0.015 14.9 0.0 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 KEZ43018.1 - 0.021 14.1 0.0 0.043 13.1 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase His_Phos_1 PF00300.22 KEZ43019.1 - 6e-36 124.0 0.3 3e-18 66.2 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) UBX PF00789.20 KEZ43020.1 - 1.3e-06 28.5 0.0 2.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 KEZ43020.1 - 2.5e-05 24.0 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain SUB1_ProdP9 PF18213.1 KEZ43020.1 - 0.0084 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 Dynein_light PF01221.18 KEZ43020.1 - 0.17 12.2 0.0 42 4.5 0.0 3.2 3 0 0 3 3 3 0 Dynein light chain type 1 DUF1682 PF07946.14 KEZ43020.1 - 5.9 6.0 12.6 9 5.4 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pan3_PK PF18101.1 KEZ43021.1 - 4.1e-61 205.0 0.1 6.6e-61 204.3 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KEZ43021.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Caprin-1_dimer PF18293.1 KEZ43021.1 - 0.014 15.8 0.1 0.1 13.1 0.1 2.3 2 0 0 2 2 2 0 Caprin-1 dimerization domain TFIIA PF03153.13 KEZ43021.1 - 1.6 8.6 8.0 3.6 7.5 8.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HET PF06985.11 KEZ43022.1 - 7.1e-24 84.8 0.1 1.1e-23 84.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec2p PF06428.11 KEZ43023.1 - 4.6e-27 93.8 23.2 4.6e-27 93.8 23.2 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF5401 PF17380.2 KEZ43023.1 - 0.29 9.1 22.4 0.43 8.6 22.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF3450 PF11932.8 KEZ43023.1 - 3.3 6.9 25.3 2 7.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF5339 PF17274.2 KEZ43023.1 - 3.7 8.5 21.4 1.5 9.7 7.7 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5339) DUF4407 PF14362.6 KEZ43023.1 - 4.3 6.6 17.5 7.1 5.9 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S46 PF10459.9 KEZ43023.1 - 5.5 5.5 15.9 7.7 5.0 15.9 1.1 1 0 0 1 1 1 0 Peptidase S46 Ank_2 PF12796.7 KEZ43024.1 - 9.3e-56 186.4 9.6 8.8e-17 61.5 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ43024.1 - 9.5e-42 139.7 4.7 8e-06 26.1 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KEZ43024.1 - 1.8e-40 132.2 0.1 0.0012 19.1 0.0 9.2 9 0 0 9 9 9 8 Ankyrin repeat HET PF06985.11 KEZ43024.1 - 3.8e-40 137.6 0.2 8e-40 136.6 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 KEZ43024.1 - 5.1e-29 100.3 1.2 1.8e-08 34.7 0.0 6.1 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ43024.1 - 9.7e-27 92.7 3.8 2.5e-06 27.7 0.0 7.1 2 1 5 7 7 7 7 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KEZ43024.1 - 0.0011 18.8 13.8 6.9 6.6 0.1 7.7 9 0 0 9 9 9 2 von Willebrand factor type A C-terminal domain HisG_C PF08029.11 KEZ43024.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 HisG, C-terminal domain PMT PF02366.18 KEZ43025.1 - 1.9e-81 273.2 15.9 3.5e-81 272.4 15.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KEZ43025.1 - 2.3e-66 223.2 9.6 2.3e-66 223.2 9.6 2.2 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KEZ43025.1 - 8.2e-47 159.5 0.1 1.6e-46 158.5 0.1 1.4 1 0 0 1 1 1 1 MIR domain CCSMST1 PF15013.6 KEZ43025.1 - 0.02 15.1 0.0 0.084 13.1 0.0 2.1 1 0 0 1 1 1 0 CCSMST1 family zf-C2H2 PF00096.26 KEZ43026.1 - 4.6e-07 29.9 8.2 0.00073 19.9 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ43026.1 - 0.0015 19.2 6.4 0.034 15.0 1.8 2.9 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KEZ43026.1 - 0.0035 17.5 0.8 0.0047 17.1 0.8 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-Di19 PF05605.12 KEZ43026.1 - 0.0044 17.3 0.9 0.01 16.1 0.9 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 KEZ43026.1 - 0.05 14.1 4.8 2 9.0 0.3 3.0 2 0 0 2 2 2 0 Zinc-finger double domain Med31 PF05669.12 KEZ43029.1 - 9.8e-38 128.1 1.3 1.2e-37 127.8 1.3 1.0 1 0 0 1 1 1 1 SOH1 HisG_C PF08029.11 KEZ43030.1 - 0.1 12.8 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain CFEM PF05730.11 KEZ43031.1 - 6.6e-08 32.5 13.7 1.3e-07 31.6 13.7 1.5 1 0 0 1 1 1 1 CFEM domain PRP21_like_P PF12230.8 KEZ43032.1 - 1.4e-54 185.3 10.9 2.5e-27 96.2 3.3 2.3 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KEZ43032.1 - 4.1e-40 135.6 2.6 1.1e-21 76.6 0.2 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KEZ43032.1 - 0.0014 18.2 0.4 0.0028 17.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger SNARE PF05739.19 KEZ43033.1 - 1.3e-13 50.7 0.1 3.6e-13 49.3 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KEZ43033.1 - 3e-09 35.8 1.9 3.2e-09 35.7 0.2 2.1 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KEZ43033.1 - 0.00012 21.8 1.0 0.00012 21.8 1.0 2.8 2 1 1 3 3 3 1 Syntaxin Prominin PF05478.11 KEZ43033.1 - 0.0024 15.9 3.4 0.12 10.3 1.3 2.2 2 0 0 2 2 2 2 Prominin Syntaxin-18_N PF10496.9 KEZ43033.1 - 0.0093 16.2 0.8 0.078 13.2 0.1 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.9 KEZ43033.1 - 0.073 13.4 2.4 0.71 10.2 0.2 3.1 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.21 KEZ43033.1 - 0.13 12.1 8.5 1.3 8.8 1.0 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1759 PF03564.15 KEZ43033.1 - 0.15 12.0 1.9 0.28 11.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF4988 PF16378.5 KEZ43033.1 - 0.15 11.7 4.8 7.5 6.2 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function Dynamin_M PF01031.20 KEZ43033.1 - 0.21 10.8 3.6 0.15 11.2 1.6 1.7 2 0 0 2 2 2 0 Dynamin central region DUF948 PF06103.11 KEZ43033.1 - 0.32 11.3 1.6 5.1 7.4 0.0 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 KEZ43033.1 - 0.63 10.3 7.9 5.2 7.4 0.2 3.8 4 1 0 4 4 4 0 Uncharacterized conserved protein DUF16 PF01519.16 KEZ43033.1 - 1.2 9.6 9.9 0.16 12.5 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KEZ43033.1 - 1.6 8.8 5.9 1.8 8.6 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 KEZ43033.1 - 1.8 7.8 5.8 1.4 8.1 1.8 2.3 2 1 0 2 2 2 0 Invariant surface glycoprotein NPV_P10 PF05531.12 KEZ43033.1 - 2.2 8.8 7.2 76 3.9 0.2 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.21 KEZ43034.1 - 7.7e-49 166.5 0.0 5.8e-47 160.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 KEZ43035.1 - 7.6e-24 83.7 0.0 1.7e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ43035.1 - 5.1e-16 58.8 0.3 8.8e-16 58.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ43035.1 - 3.5e-09 36.5 0.2 0.00039 20.0 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KEZ43035.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KEZ43035.1 - 0.097 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.6 KEZ43036.1 - 1e-59 202.0 2.8 1.2e-59 201.7 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43036.1 - 1e-49 168.7 1.9 1.2e-49 168.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ43036.1 - 3.5e-09 36.8 1.4 1.3e-08 35.0 1.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ43036.1 - 2.7e-05 23.8 0.1 9.4e-05 22.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ43036.1 - 0.088 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 KEZ43036.1 - 0.12 11.8 0.3 1.3 8.3 0.0 2.1 1 1 1 2 2 2 0 ThiF family NACHT PF05729.12 KEZ43037.1 - 2.8e-07 30.6 0.0 8.2e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ43037.1 - 6.6e-05 23.4 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SesA PF17107.5 KEZ43037.1 - 0.00011 22.4 2.5 0.00019 21.6 0.0 2.5 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KEZ43037.1 - 0.00011 22.4 0.0 0.00054 20.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEZ43037.1 - 0.036 14.4 0.2 0.12 12.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 KEZ43037.1 - 0.043 14.3 0.2 0.15 12.6 0.1 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KEZ43037.1 - 0.046 13.5 0.1 0.098 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ43037.1 - 0.05 14.1 0.2 0.05 14.1 0.2 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEZ43037.1 - 0.12 13.0 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain HAUS2 PF15003.6 KEZ43037.1 - 0.14 11.8 1.4 0.41 10.3 1.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 adh_short_C2 PF13561.6 KEZ43038.1 - 2.3e-54 184.4 0.0 2.9e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43038.1 - 5.9e-52 176.0 0.0 7e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ43038.1 - 2e-10 40.8 0.1 8.1e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KEZ43038.1 - 1.1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KEZ43038.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CHAP PF05257.16 KEZ43038.1 - 0.25 11.9 0.8 17 6.1 0.2 2.5 2 1 0 2 2 2 0 CHAP domain DUF1100 PF06500.11 KEZ43039.1 - 1.7e-10 40.3 0.0 2.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 KEZ43039.1 - 1e-06 28.4 0.1 1.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEZ43039.1 - 4.1e-06 26.6 0.0 6.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 KEZ43039.1 - 0.0041 16.8 0.0 0.023 14.3 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 KEZ43039.1 - 0.025 15.2 2.3 0.053 14.1 1.2 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Esterase_phd PF10503.9 KEZ43039.1 - 0.045 13.2 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KEZ43039.1 - 0.05 12.9 0.0 0.72 9.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 KEZ43039.1 - 0.14 11.7 0.0 1.6 8.2 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Acetyltransf_1 PF00583.25 KEZ43040.1 - 2e-10 40.9 0.1 2.5e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ43040.1 - 3.4e-08 33.8 0.4 5e-08 33.2 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ43040.1 - 3.6e-07 30.2 0.1 4.8e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 KEZ43040.1 - 0.02 13.4 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Lyase_1 PF00206.20 KEZ43041.1 - 4.3e-110 368.0 0.0 5.8e-110 367.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KEZ43041.1 - 2.9e-22 78.8 0.0 7.4e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus TFIIS_C PF01096.18 KEZ43042.1 - 5.2e-20 71.0 2.4 5.2e-20 71.0 2.4 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KEZ43042.1 - 1e-07 31.7 0.1 2.3e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 KEZ43042.1 - 0.043 14.0 2.6 0.35 11.1 1.0 2.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DUF1687 PF07955.11 KEZ43043.1 - 5.1e-33 114.3 0.1 6.8e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) TOM6p PF15184.6 KEZ43043.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog ArsC PF03960.15 KEZ43043.1 - 0.04 13.9 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 ArsC family Ribophorin_II PF05817.14 KEZ43043.1 - 0.047 12.3 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_L14e PF01929.17 KEZ43044.1 - 2.8e-27 95.0 2.4 3.9e-27 94.6 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KEZ43044.1 - 0.0019 18.1 0.1 0.0045 16.9 0.1 1.6 1 0 0 1 1 1 1 KOW motif BAH PF01426.18 KEZ43044.1 - 0.07 13.0 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 BAH domain NAC PF01849.18 KEZ43045.1 - 5.9e-23 80.6 0.2 1.9e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 NAC domain CENP-B_dimeris PF09026.10 KEZ43045.1 - 0.044 14.2 8.5 4.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.12 KEZ43045.1 - 0.39 10.2 9.6 0.037 13.5 1.4 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Cytomega_UL84 PF06284.11 KEZ43045.1 - 1.2 7.5 6.3 0.099 11.1 1.9 1.4 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein CDC45 PF02724.14 KEZ43045.1 - 3.3 5.9 10.8 0.13 10.6 4.4 1.7 2 0 0 2 2 2 0 CDC45-like protein PQ-loop PF04193.14 KEZ43046.1 - 1.1e-36 124.4 14.4 3.5e-21 74.7 0.6 3.1 3 0 0 3 3 3 2 PQ loop repeat S1-P1_nuclease PF02265.16 KEZ43047.1 - 6e-68 229.4 0.1 6.8e-68 229.2 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PSI_PSAK PF01241.18 KEZ43047.1 - 0.042 13.9 0.2 0.085 12.9 0.2 1.4 1 0 0 1 1 1 0 Photosystem I psaG / psaK Semialdhyde_dhC PF02774.18 KEZ43050.1 - 1.1e-36 126.7 0.0 1.5e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KEZ43050.1 - 1.1e-29 103.4 0.0 2e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF5033 PF16436.5 KEZ43051.1 - 0.22 11.5 0.1 0.34 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) GPI2 PF06432.11 KEZ43052.1 - 7.4e-125 416.0 2.4 9.8e-125 415.6 2.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CopD PF05425.13 KEZ43052.1 - 0.035 14.5 3.2 0.086 13.2 2.0 2.3 2 0 0 2 2 2 0 Copper resistance protein D Gly-zipper_Omp PF13488.6 KEZ43052.1 - 8.2 6.5 14.6 2.6 8.1 4.2 2.4 2 0 0 2 2 2 0 Glycine zipper FAM199X PF15814.5 KEZ43052.1 - 8.9 5.3 8.4 14 4.6 8.4 1.2 1 0 0 1 1 1 0 Protein family FAM199X Ras PF00071.22 KEZ43053.1 - 6e-43 146.2 0.0 7.8e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ43053.1 - 4.6e-11 43.0 0.0 7.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ43053.1 - 1.3e-05 24.8 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KEZ43053.1 - 5.9e-05 22.7 0.0 7.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEZ43053.1 - 0.033 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase zf-MYND PF01753.18 KEZ43054.1 - 3.2e-05 23.9 11.8 0.00095 19.2 0.0 3.6 2 1 2 4 4 4 2 MYND finger ECM11 PF15463.6 KEZ43054.1 - 0.029 14.9 9.8 0.057 14.0 0.7 4.0 3 1 1 4 4 4 0 Extracellular mutant protein 11 PHD PF00628.29 KEZ43054.1 - 0.036 14.0 0.8 0.036 14.0 0.8 3.2 3 1 1 4 4 4 0 PHD-finger PLATZ PF04640.14 KEZ43054.1 - 0.05 14.2 16.7 0.74 10.5 1.8 3.8 2 1 0 2 2 2 0 PLATZ transcription factor zf-HIT PF04438.16 KEZ43054.1 - 0.23 11.4 9.9 0.48 10.3 0.9 3.0 2 1 0 2 2 2 0 HIT zinc finger Arg_decarbox_C PF17944.1 KEZ43054.1 - 2.1 8.9 4.7 35 5.1 0.2 2.9 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension PspB PF06667.12 KEZ43054.1 - 3.1 7.9 7.4 0.23 11.5 0.3 2.5 2 0 0 2 2 2 0 Phage shock protein B zf-C6H2 PF15801.5 KEZ43054.1 - 4.8 7.6 17.8 0.4 11.0 4.8 2.8 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Glyco_trans_1_2 PF13524.6 KEZ43054.1 - 6.6 7.2 6.5 1.7 9.1 0.5 2.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 SF3b10 PF07189.11 KEZ43055.1 - 4.7e-36 122.8 0.0 5.7e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 KEZ43056.1 - 7.2e-34 117.3 0.1 1.2e-33 116.6 0.1 1.3 1 0 0 1 1 1 1 MAGE family SLS PF14611.6 KEZ43057.1 - 6.8e-25 88.2 1.6 1.5e-24 87.0 1.6 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.27 KEZ43058.1 - 5.8e-46 156.5 0.0 1e-45 155.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KEZ43058.1 - 7.8e-43 145.3 0.0 1.7e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KEZ43058.1 - 3.7e-16 59.3 0.9 1.2e-15 57.6 0.9 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ43058.1 - 0.00018 21.5 0.1 0.00048 20.2 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KEZ43058.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family GTP_EFTU_D4 PF14578.6 KEZ43058.1 - 0.043 13.7 0.3 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PDZ PF00595.24 KEZ43058.1 - 0.11 12.8 0.7 0.47 10.9 0.1 2.4 2 0 0 2 2 2 0 PDZ domain Adaptin_N PF01602.20 KEZ43059.1 - 2e-115 386.3 1.6 2.6e-115 386.0 1.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KEZ43059.1 - 1.4e-56 190.8 3.1 3.5e-56 189.5 3.1 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KEZ43059.1 - 5.4e-35 120.0 0.5 1.5e-34 118.5 0.5 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KEZ43059.1 - 1.4e-17 63.8 1.3 9e-12 45.2 0.0 5.4 2 1 3 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KEZ43059.1 - 1.5e-08 34.9 10.5 0.026 14.6 0.1 5.1 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Alpha_adaptin_C PF02296.16 KEZ43059.1 - 0.0022 18.2 0.1 0.0097 16.1 0.0 2.2 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.16 KEZ43059.1 - 0.004 17.7 0.4 11 7.0 0.0 4.8 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 KEZ43059.1 - 0.011 15.9 1.5 1.1 9.5 0.1 3.7 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KEZ43059.1 - 0.04 13.5 0.1 0.04 13.5 0.1 3.3 4 0 0 4 4 4 0 CLASP N terminal E2F_CC-MB PF16421.5 KEZ43059.1 - 0.11 12.9 0.4 0.77 10.2 0.1 2.4 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF5010 PF16402.5 KEZ43059.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT PF02985.22 KEZ43059.1 - 0.23 11.8 9.9 2.5 8.6 0.4 5.6 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 KEZ43059.1 - 0.57 10.7 2.5 1.3 9.6 0.2 3.0 3 0 0 3 3 3 0 HEAT-like repeat CDP-OH_P_transf PF01066.21 KEZ43060.1 - 2.5e-17 63.4 0.1 2.5e-17 63.4 0.1 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HATPase_c PF02518.26 KEZ43061.1 - 1.7e-26 92.9 0.3 3.3e-26 92.0 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ43061.1 - 3.2e-20 72.4 0.0 1.4e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 KEZ43061.1 - 3.6e-20 72.0 3.4 2.1e-11 43.9 0.7 3.6 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 KEZ43061.1 - 1.8e-19 69.6 0.1 4e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KEZ43061.1 - 5.4e-09 36.0 0.0 2.2e-05 24.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KEZ43061.1 - 7.5e-08 32.6 0.2 6.8e-06 26.3 0.1 2.9 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 KEZ43061.1 - 1.6e-05 25.1 0.0 0.4 11.0 0.0 3.7 3 0 0 3 3 3 2 PAS domain DUF3466 PF11949.8 KEZ43061.1 - 0.14 10.7 0.1 0.23 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Cytochrom_B561 PF03188.16 KEZ43062.1 - 9.7e-17 61.4 5.0 1.9e-16 60.5 5.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4271 PF14093.6 KEZ43062.1 - 0.0045 16.9 1.4 0.0045 16.9 1.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4271) DUF4079 PF13301.6 KEZ43062.1 - 0.7 10.0 15.2 86 3.3 15.2 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) PepSY_TM PF03929.16 KEZ43062.1 - 6.7 6.3 14.3 37 3.8 14.0 2.2 1 1 0 1 1 1 0 PepSY-associated TM region Allantoicase PF03561.15 KEZ43063.1 - 1e-96 320.6 0.2 1.2e-47 161.6 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 KEZ43064.1 - 9.4e-32 109.4 0.3 1.8e-31 108.4 0.3 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KEZ43064.1 - 1.3e-13 51.3 0.0 4.3e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43064.1 - 2.1e-11 44.1 0.5 8.2e-07 29.5 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43064.1 - 2.8e-10 40.2 0.3 0.0037 17.7 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEZ43064.1 - 4.3e-09 36.5 0.0 1.5e-06 28.4 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43064.1 - 2.2e-07 30.6 0.0 0.043 14.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat DUF2336 PF10098.9 KEZ43064.1 - 0.13 11.7 1.7 0.56 9.6 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2336) RabGAP-TBC PF00566.18 KEZ43065.1 - 2.6e-32 112.3 0.0 4e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HATPase_c PF02518.26 KEZ43066.1 - 3.6e-30 104.8 0.0 8.1e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ43066.1 - 7.9e-21 74.3 0.1 1.8e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KEZ43066.1 - 3.2e-19 68.7 0.5 1.5e-18 66.6 0.5 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KEZ43066.1 - 8.5e-17 61.7 0.0 6.3e-16 58.9 0.0 2.6 2 0 0 2 2 1 1 GAF domain AAA_16 PF13191.6 KEZ43066.1 - 2.6e-14 54.0 4.1 3.1e-14 53.7 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain GAF PF01590.26 KEZ43066.1 - 1.6e-09 38.5 0.0 4.8e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KEZ43066.1 - 5.4e-06 26.0 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.12 KEZ43066.1 - 0.00025 21.0 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain HATPase_c_3 PF13589.6 KEZ43066.1 - 0.00027 20.8 0.0 0.00062 19.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MeaB PF03308.16 KEZ43066.1 - 0.014 14.4 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GAF_3 PF13492.6 KEZ43066.1 - 0.019 15.3 0.0 0.055 13.8 0.0 1.8 1 0 0 1 1 1 0 GAF domain Pkinase_Tyr PF07714.17 KEZ43066.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase NB-ARC PF00931.22 KEZ43066.1 - 0.2 10.8 0.1 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain HisKA_3 PF07730.13 KEZ43066.1 - 0.21 12.1 4.0 0.78 10.3 0.1 3.0 2 0 0 2 2 2 0 Histidine kinase NAD_binding_8 PF13450.6 KEZ43067.1 - 1.1e-08 35.2 0.0 2.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEZ43067.1 - 1e-06 28.3 0.0 1.3e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KEZ43067.1 - 0.00069 18.9 0.0 0.02 14.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ43067.1 - 0.0059 15.9 0.1 0.0089 15.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEZ43067.1 - 0.0081 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ43067.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KEZ43067.1 - 0.025 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KEZ43067.1 - 0.028 14.7 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KEZ43067.1 - 0.031 13.0 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 KEZ43067.1 - 0.064 12.8 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ43067.1 - 0.067 12.2 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEZ43067.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KEZ43067.1 - 0.12 12.4 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding TPT PF03151.16 KEZ43068.1 - 5.8e-21 75.1 21.2 7e-21 74.8 21.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEZ43068.1 - 7.7e-05 22.9 33.3 0.0008 19.6 14.8 2.7 3 0 0 3 3 3 2 EamA-like transporter family Ribosomal_L27e PF01777.18 KEZ43069.1 - 3.8e-38 129.7 3.1 5.9e-38 129.1 3.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KEZ43069.1 - 0.016 15.2 0.7 0.016 15.2 0.7 2.3 3 0 0 3 3 3 0 KOW motif Ssl1 PF04056.14 KEZ43070.1 - 3.4e-73 245.6 0.0 4.4e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KEZ43070.1 - 1.3e-20 73.4 7.2 1.3e-20 73.4 7.2 2.7 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KEZ43070.1 - 1.6e-14 54.4 0.0 4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEZ43070.1 - 0.00072 19.9 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4796 PF16044.5 KEZ43070.1 - 0.72 9.4 10.2 0.23 11.0 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) Chs7 PF12271.8 KEZ43071.1 - 4e-112 374.3 3.0 4.6e-112 374.1 3.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF347 PF03988.12 KEZ43071.1 - 2.6 8.3 0.0 2.6 8.3 0.0 4.5 5 1 1 6 6 6 0 Repeat of Unknown Function (DUF347) Sugar_tr PF00083.24 KEZ43072.1 - 1e-94 318.0 15.2 1.2e-94 317.7 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43072.1 - 2.4e-21 76.1 46.9 5e-20 71.7 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 KEZ43073.1 - 2.2e-39 133.3 8.2 2.2e-14 53.2 0.8 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2293 PF10056.9 KEZ43074.1 - 1.8e-32 111.4 0.5 4.6e-32 110.1 0.5 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) CUE PF02845.16 KEZ43075.1 - 4.7e-12 45.4 0.0 7.8e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain Ank_4 PF13637.6 KEZ43076.1 - 7.3e-27 93.4 2.7 1.7e-09 38.0 0.0 5.6 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ43076.1 - 1.6e-25 89.5 0.5 1.6e-08 35.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ43076.1 - 4.4e-17 61.9 3.9 5.2e-05 23.5 0.1 5.3 3 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43076.1 - 1.2e-16 59.1 4.6 0.00033 20.9 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KEZ43076.1 - 3.3e-14 52.6 6.8 0.0048 17.3 0.0 6.8 7 1 1 8 8 8 3 Ankyrin repeat SPX PF03105.19 KEZ43076.1 - 1.3e-11 45.1 8.1 3.4e-09 37.1 1.0 2.2 1 1 1 2 2 2 2 SPX domain GDPD PF03009.17 KEZ43076.1 - 0.00011 22.0 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family OmpH PF03938.14 KEZ43076.1 - 7.6 6.9 5.9 14 6.0 5.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Coa1 PF08695.10 KEZ43078.1 - 7.9e-42 141.7 0.0 1.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TRAP-gamma PF07074.12 KEZ43078.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) PITH PF06201.13 KEZ43079.1 - 4.3e-44 150.4 0.1 5e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 PITH domain NACHT PF05729.12 KEZ43080.1 - 3.5e-08 33.5 0.0 9.1e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 KEZ43080.1 - 2.1e-05 24.0 1.6 9.2e-05 21.9 1.6 2.2 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KEZ43080.1 - 2.4e-05 24.6 0.4 0.00038 20.8 0.0 2.9 3 1 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KEZ43080.1 - 0.00024 21.5 0.6 0.0047 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RFC1 PF08519.12 KEZ43080.1 - 0.029 14.5 0.1 0.07 13.3 0.1 1.6 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain NB-ARC PF00931.22 KEZ43080.1 - 0.11 11.6 0.0 0.31 10.2 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain MerR-DNA-bind PF09278.11 KEZ43080.1 - 0.8 10.3 4.7 16 6.1 0.2 4.3 5 0 0 5 5 5 0 MerR, DNA binding Rrn6 PF10214.9 KEZ43081.1 - 7.9e-110 368.7 4.3 1e-109 368.4 4.3 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 KEZ43082.1 - 1.8e-24 85.7 0.0 4.6e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF4407 PF14362.6 KEZ43082.1 - 0.071 12.5 6.9 0.11 11.8 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KEZ43082.1 - 1.6 7.8 9.3 2.5 7.1 9.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KEZ43082.1 - 7.1 5.8 8.2 11 5.2 8.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein zinc_ribbon_6 PF14599.6 KEZ43083.1 - 3.6e-25 87.7 3.1 3.6e-25 87.7 3.1 4.0 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 KEZ43083.1 - 5.3e-18 65.3 23.5 5.3e-18 65.3 23.5 3.7 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KEZ43083.1 - 1.8e-08 34.5 6.8 1.8e-08 34.5 6.8 5.4 2 2 5 7 7 7 1 Ring finger domain zf-RING_UBOX PF13445.6 KEZ43083.1 - 2.9e-07 30.4 4.3 2.9e-07 30.4 4.3 3.7 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEZ43083.1 - 2e-06 27.6 5.0 2e-06 27.6 5.0 5.6 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEZ43083.1 - 1.7e-05 24.6 7.7 1.7e-05 24.6 7.7 6.2 2 1 4 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ43083.1 - 0.00013 21.7 8.1 0.00013 21.7 8.1 5.1 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KEZ43083.1 - 0.01 15.7 2.3 0.01 15.7 2.3 6.1 5 3 2 7 7 7 0 Prokaryotic RING finger family 1 zf-RING_11 PF17123.5 KEZ43083.1 - 0.017 14.8 2.6 0.017 14.8 2.6 5.0 5 0 0 5 5 5 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 KEZ43083.1 - 0.1 13.1 3.5 3.4 8.2 0.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain PMT PF02366.18 KEZ43084.1 - 7e-87 291.1 14.8 7e-87 291.1 14.8 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KEZ43084.1 - 1e-63 214.5 16.8 1e-63 214.5 16.8 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KEZ43084.1 - 2.3e-37 128.7 0.3 3.5e-37 128.0 0.3 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 KEZ43084.1 - 0.0099 15.7 2.1 0.38 10.6 1.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2976) Choline_transpo PF04515.12 KEZ43085.1 - 9e-30 104.0 20.7 9e-30 104.0 20.7 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter WW PF00397.26 KEZ43086.1 - 2.1e-10 40.5 6.9 3.6e-10 39.8 6.9 1.4 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.10 KEZ43087.1 - 4.1e-28 98.0 0.0 5.6e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 KEZ43087.1 - 0.039 14.2 0.2 0.079 13.2 0.2 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain FAD_binding_4 PF01565.23 KEZ43088.1 - 2.3e-07 30.6 0.1 2.8e-07 30.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain CPSase_L_D2 PF02786.17 KEZ43089.1 - 4.5e-64 215.8 0.0 8e-64 215.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KEZ43089.1 - 1.2e-40 138.5 0.2 4.2e-40 136.7 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ43089.1 - 8.7e-19 67.6 0.0 2.1e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 KEZ43089.1 - 1.7e-07 31.0 0.1 7.4e-07 28.9 0.0 2.1 1 1 1 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KEZ43089.1 - 2.7e-07 30.8 0.0 4.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEZ43089.1 - 7.8e-07 28.8 0.0 2.2e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 KEZ43089.1 - 0.0022 17.3 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 KEZ43089.1 - 0.0028 17.0 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp NYD-SP12_N PF15015.6 KEZ43089.1 - 0.015 13.7 0.0 0.025 12.9 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal YqfD PF06898.11 KEZ43089.1 - 0.036 12.9 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Biotin_lipoyl PF00364.22 KEZ43089.1 - 0.063 13.1 0.1 0.89 9.4 0.1 2.7 1 1 0 1 1 1 0 Biotin-requiring enzyme Fungal_trans PF04082.18 KEZ43090.1 - 6e-05 22.2 0.0 8.2e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3500 PF12006.8 KEZ43091.1 - 5.2e-54 183.7 0.0 1.9e-45 155.7 0.0 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3500) MFS_1 PF07690.16 KEZ43093.1 - 6.7e-22 77.9 22.3 1.4e-13 50.5 8.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily HMGL-like PF00682.19 KEZ43094.1 - 1.7e-45 155.6 0.0 2.6e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 KEZ43094.1 - 2.9e-40 138.2 0.0 4.5e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ43094.1 - 1.6e-21 77.2 0.1 2.1e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 KEZ43095.1 - 4e-86 289.6 0.0 2.9e-50 171.4 0.0 2.9 2 1 0 2 2 2 2 Carboxyl transferase domain MFS_1 PF07690.16 KEZ43096.1 - 2.7e-20 72.6 28.2 3.4e-20 72.3 28.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KEZ43096.1 - 0.053 13.3 4.7 4 7.2 0.1 2.6 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAA_hydro_N_2 PF18288.1 KEZ43097.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 DUF269 PF03270.13 KEZ43097.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF269 rRNA_proc-arch PF13234.6 KEZ43099.1 - 0.068 13.1 2.5 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 rRNA-processing arch domain TauD PF02668.16 KEZ43100.1 - 3.9e-31 108.8 0.0 5.7e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fasciclin PF02469.22 KEZ43101.1 - 3.4e-43 146.9 0.2 3.7e-20 72.4 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain PBP PF01161.20 KEZ43102.1 - 3.4e-09 37.1 0.0 4.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Aldedh PF00171.22 KEZ43103.1 - 1.9e-44 152.0 0.0 4e-24 85.0 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF3328 PF11807.8 KEZ43103.1 - 2.4e-27 96.2 0.0 5.6e-26 91.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 KEZ43105.1 - 5.8e-15 55.1 37.3 3e-11 42.9 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43105.1 - 3.1e-14 52.7 22.0 2.2e-13 49.9 22.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.24 KEZ43106.1 - 9.1e-44 150.5 0.0 1.1e-43 150.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ43106.1 - 2.2e-06 27.2 0.0 0.013 14.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ43106.1 - 8e-06 25.2 0.0 0.048 12.7 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 KEZ43106.1 - 4.3e-05 22.8 0.0 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KEZ43106.1 - 0.00014 20.7 0.0 0.078 11.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 KEZ43106.1 - 0.00025 21.2 0.0 0.00062 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ43106.1 - 0.0025 17.1 0.0 0.0096 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ43106.1 - 0.0031 16.8 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Glu_dehyd_C PF16912.5 KEZ43106.1 - 0.0081 15.7 0.0 0.061 12.8 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 KEZ43106.1 - 0.011 16.3 0.0 0.05 14.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ43106.1 - 0.013 15.5 0.0 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KEZ43106.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KEZ43106.1 - 0.075 12.1 0.0 11 5.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 KEZ43106.1 - 0.15 12.3 0.0 1.4 9.2 0.0 2.5 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KEZ43106.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.6 KEZ43108.1 - 1.7e-43 148.9 0.2 3.2e-38 131.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43108.1 - 5.3e-43 146.8 0.1 6.5e-43 146.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ43108.1 - 8.6e-14 51.8 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ43108.1 - 7.8e-05 22.2 0.0 0.00032 20.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KEZ43108.1 - 0.026 14.4 1.2 2 8.2 0.5 2.2 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 KEZ43108.1 - 0.036 13.2 0.0 0.05 12.7 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 KEZ43108.1 - 0.042 13.2 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 KEZ43108.1 - 0.072 13.7 0.3 0.14 12.7 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YAcAr PF10686.9 KEZ43108.1 - 0.074 13.0 0.2 3 7.8 0.1 2.5 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family GDP_Man_Dehyd PF16363.5 KEZ43108.1 - 0.085 12.2 0.0 0.31 10.4 0.0 2.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ribosomal_L26 PF16906.5 KEZ43108.1 - 0.18 12.3 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Cupredoxin_1 PF13473.6 KEZ43109.1 - 0.086 13.0 0.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Glucosamine_iso PF01182.20 KEZ43110.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_S8 PF00082.22 KEZ43111.1 - 0.052 12.8 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Subtilase family DUF3134 PF11332.8 KEZ43111.1 - 0.071 13.4 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) MFS_1 PF07690.16 KEZ43112.1 - 1.7e-39 135.7 16.2 1.1e-38 133.1 16.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ThrE PF06738.12 KEZ43112.1 - 4.4 6.6 11.6 0.051 12.9 2.4 2.3 2 1 0 2 2 2 0 Putative threonine/serine exporter Glyco_hydro_10 PF00331.20 KEZ43113.1 - 1.6e-92 310.0 0.2 1.9e-92 309.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 UDPG_MGDP_dh_C PF03720.15 KEZ43113.1 - 0.17 12.4 0.1 1.5 9.3 0.1 2.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ABC_membrane PF00664.23 KEZ43114.1 - 4.7e-44 151.1 10.7 6e-44 150.7 10.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ43114.1 - 1.2e-34 119.8 0.0 2.3e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KEZ43114.1 - 3.9e-05 23.2 0.1 0.0093 15.4 0.1 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ43114.1 - 0.00036 20.4 0.1 0.0043 16.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KEZ43114.1 - 0.00063 20.0 0.0 0.0026 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ43114.1 - 0.0026 18.2 0.1 0.007 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ43114.1 - 0.0089 15.9 0.0 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 KEZ43114.1 - 0.0091 16.0 0.0 0.055 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEZ43114.1 - 0.011 15.8 0.0 0.059 13.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KEZ43114.1 - 0.015 15.0 0.1 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KEZ43114.1 - 0.019 14.5 0.0 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEZ43114.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ43114.1 - 0.027 14.9 0.0 0.26 11.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEZ43114.1 - 0.028 14.3 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 KEZ43114.1 - 0.032 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KEZ43114.1 - 0.032 14.5 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KEZ43114.1 - 0.033 13.1 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.6 KEZ43114.1 - 0.062 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEZ43114.1 - 0.089 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ43114.1 - 0.089 13.3 0.0 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ43114.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KEZ43114.1 - 0.14 12.4 0.9 2.5 8.4 0.4 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.16 KEZ43115.1 - 2.6e-30 105.6 29.6 3.2e-30 105.2 29.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_4 PF13637.6 KEZ43116.1 - 0.00015 22.2 0.4 5.2 7.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ43116.1 - 0.00055 20.5 0.0 0.11 13.0 0.0 4.0 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ43116.1 - 0.0012 19.2 0.0 1.7 9.2 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KEZ43116.1 - 0.049 14.0 0.1 24 5.4 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeats (many copies) p450 PF00067.22 KEZ43118.1 - 2.6e-69 234.2 0.0 3e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3136 PF11334.8 KEZ43118.1 - 0.045 13.6 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Amino_oxidase PF01593.24 KEZ43119.1 - 1.6e-49 169.5 0.0 2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ43119.1 - 6e-12 45.6 0.8 1.4e-11 44.5 0.3 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ43119.1 - 1.8e-09 37.6 1.5 1.5e-08 34.6 1.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ43119.1 - 5.6e-09 35.6 0.3 1.3e-07 31.1 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KEZ43119.1 - 1.4e-08 34.6 0.0 3.5e-08 33.2 0.0 1.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ43119.1 - 2.5e-06 26.9 0.0 4.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KEZ43119.1 - 4.9e-06 25.5 0.1 1.4e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 KEZ43119.1 - 7e-06 25.5 0.1 3.5e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ43119.1 - 1.5e-05 24.3 0.2 5.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KEZ43119.1 - 2.2e-05 23.9 0.0 0.00017 21.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KEZ43119.1 - 0.0014 19.2 0.1 0.0037 17.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ43119.1 - 0.0015 17.7 0.1 0.0028 16.7 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEZ43119.1 - 0.075 12.3 0.2 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 KEZ43119.1 - 0.15 10.6 0.0 0.3 9.6 0.0 1.4 2 0 0 2 2 2 0 GDP dissociation inhibitor Fungal_trans_2 PF11951.8 KEZ43120.1 - 6.6e-24 84.4 0.1 7.3e-24 84.3 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Styelin PF17562.2 KEZ43120.1 - 0.033 14.5 0.1 12 6.3 0.0 2.6 2 1 0 2 2 2 0 Styelin NmrA PF05368.13 KEZ43121.1 - 7.7e-16 58.4 0.0 4.1e-15 56.0 0.0 1.8 1 1 1 2 2 2 1 NmrA-like family KR PF08659.10 KEZ43121.1 - 8.6e-06 25.8 0.0 2.4e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KEZ43121.1 - 0.00097 19.1 0.0 0.0027 17.6 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KEZ43121.1 - 0.0067 16.5 0.1 0.017 15.2 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KEZ43121.1 - 0.033 13.7 0.1 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF5022 PF16425.5 KEZ43121.1 - 0.081 12.4 0.3 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5022) HgmA PF04209.13 KEZ43122.1 - 2.3e-179 596.6 0.1 2.7e-179 596.3 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.6 KEZ43123.1 - 1e-49 169.5 58.2 1.3e-49 169.2 58.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ43123.1 - 6e-17 61.4 46.0 8.8e-17 60.8 46.0 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.19 KEZ43124.1 - 1.2e-16 60.9 2.9 1.5e-15 57.3 2.9 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ43124.1 - 1.3e-08 34.5 0.3 0.00016 21.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ43124.1 - 1e-07 31.9 2.3 0.0021 17.7 0.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ43124.1 - 3.4e-07 29.7 0.1 8.1e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ43124.1 - 6.7e-05 23.0 0.1 0.0002 21.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ43124.1 - 0.00019 22.0 0.2 0.01 16.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ43124.1 - 0.00074 18.3 0.2 0.013 14.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KEZ43124.1 - 0.00087 18.8 0.2 0.0016 17.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ43124.1 - 0.012 14.8 0.2 0.15 11.1 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KEZ43124.1 - 0.017 14.4 0.3 0.096 11.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ43124.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KEZ43124.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KEZ43124.1 - 0.11 11.3 0.1 9.9 4.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase EutQ PF06249.12 KEZ43125.1 - 1.6e-05 24.7 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KEZ43125.1 - 8e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KEZ43125.1 - 0.0033 17.1 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 KEZ43125.1 - 0.021 14.5 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Pirin PF02678.16 KEZ43125.1 - 0.045 13.7 0.0 0.067 13.2 0.0 1.4 1 1 0 1 1 1 0 Pirin Aldedh PF00171.22 KEZ43126.1 - 9.8e-166 551.8 0.1 1.1e-165 551.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LPD7 PF18821.1 KEZ43126.1 - 0.22 11.7 0.8 16 5.7 0.1 2.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 AAA_16 PF13191.6 KEZ43128.1 - 5.7e-10 39.8 0.1 1.6e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KEZ43128.1 - 0.012 14.7 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KEZ43128.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KEZ43128.1 - 0.085 12.4 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KEZ43128.1 - 0.16 11.9 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SRP-alpha_N PF04086.13 KEZ43129.1 - 1.8 8.4 13.2 3 7.7 13.2 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GPI-anchored PF10342.9 KEZ43130.1 - 0.00098 19.8 0.1 0.0019 18.9 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CN_hydrolase PF00795.22 KEZ43130.1 - 0.04 13.2 0.0 0.085 12.2 0.0 1.5 2 0 0 2 2 2 0 Carbon-nitrogen hydrolase DNA_pol_A_exo1 PF01612.20 KEZ43131.1 - 2e-43 148.2 0.5 2.9e-43 147.6 0.5 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KEZ43131.1 - 1.4e-22 80.2 0.0 1.4e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 KEZ43131.1 - 8.2e-10 38.5 0.0 2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 HRDC domain SR-25 PF10500.9 KEZ43131.1 - 0.025 14.2 22.2 0.041 13.5 22.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PI3K_1B_p101 PF10486.9 KEZ43131.1 - 5.1 4.8 14.0 7 4.3 14.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Gpi1 PF05024.15 KEZ43132.1 - 5.8e-75 251.5 9.1 1e-74 250.7 9.1 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) TBCC PF07986.12 KEZ43132.1 - 1.8e-07 30.9 0.1 6.6e-07 29.1 0.0 1.9 1 1 1 2 2 2 1 Tubulin binding cofactor C 7tm_1 PF00001.21 KEZ43132.1 - 0.00014 21.3 0.5 0.0003 20.2 0.5 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TBCC_N PF16752.5 KEZ43132.1 - 0.012 16.1 0.1 0.012 16.1 0.1 2.6 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain DNA_pol3_delta PF06144.13 KEZ43132.1 - 0.16 11.8 1.5 0.3 10.8 1.5 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit U1snRNP70_N PF12220.8 KEZ43132.1 - 2.1 9.0 9.8 0.34 11.6 0.6 2.7 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal iPGM_N PF06415.13 KEZ43133.1 - 5.9e-77 258.0 0.0 8e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KEZ43133.1 - 7.7e-63 212.1 0.0 9.9e-63 211.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KEZ43133.1 - 5.3e-07 29.3 0.0 2.1e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.24 KEZ43133.1 - 0.05 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel FRQ PF09421.10 KEZ43134.1 - 4e-281 935.5 55.0 2.2e-169 565.6 31.4 2.7 1 1 1 2 2 2 2 Frequency clock protein Prefoldin PF02996.17 KEZ43135.1 - 6.9e-36 122.8 0.5 1.4e-35 121.8 0.5 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KEZ43135.1 - 0.0039 17.1 0.0 0.0039 17.1 0.0 2.5 2 1 0 3 3 3 1 Prefoldin subunit End3 PF12761.7 KEZ43135.1 - 0.031 14.4 0.5 0.06 13.5 0.3 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF1151 PF06625.11 KEZ43135.1 - 0.12 12.3 0.3 0.12 12.3 0.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1151) CRAL_TRIO PF00650.20 KEZ43136.1 - 5.4e-37 127.0 0.0 1e-36 126.1 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEZ43136.1 - 2.5e-06 27.6 0.9 3.9e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF1769 PF08588.10 KEZ43136.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Nsp1 PF11501.8 KEZ43136.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Non structural protein Nsp1 Mis14 PF08641.12 KEZ43137.1 - 7.2e-15 55.5 0.4 4.4e-14 52.9 0.0 2.4 2 1 1 3 3 3 1 Kinetochore protein Mis14 like SHMT PF00464.19 KEZ43138.1 - 9.8e-210 696.2 0.0 1.1e-209 695.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KEZ43138.1 - 0.00066 19.0 0.0 0.0014 17.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Spc7 PF08317.11 KEZ43138.1 - 0.055 12.4 0.1 0.11 11.3 0.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Beta_elim_lyase PF01212.21 KEZ43138.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KEZ43138.1 - 0.18 10.3 0.0 0.31 9.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AAA PF00004.29 KEZ43140.1 - 1.4e-45 154.9 0.3 6.1e-45 152.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEZ43140.1 - 2e-10 40.5 0.0 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KEZ43140.1 - 1.6e-08 34.7 0.4 5.7e-08 32.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEZ43140.1 - 4.3e-08 33.5 0.0 9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEZ43140.1 - 2.2e-07 31.4 0.7 3.7e-05 24.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KEZ43140.1 - 1e-06 28.1 0.2 2.2e-06 27.0 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KEZ43140.1 - 3e-05 24.3 1.0 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KEZ43140.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KEZ43140.1 - 0.00039 21.0 0.0 0.0012 19.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KEZ43140.1 - 0.00046 19.5 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 KEZ43140.1 - 0.00065 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEZ43140.1 - 0.00088 18.8 0.1 0.0033 17.0 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_3 PF17862.1 KEZ43140.1 - 0.00093 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 KEZ43140.1 - 0.0013 18.7 0.0 0.018 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KEZ43140.1 - 0.0013 18.8 0.1 0.0066 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEZ43140.1 - 0.0021 18.4 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KEZ43140.1 - 0.005 16.8 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_3 PF07726.11 KEZ43140.1 - 0.0051 16.7 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEZ43140.1 - 0.0072 16.3 0.5 0.11 12.3 0.0 2.6 2 1 1 3 3 3 1 NACHT domain AAA_33 PF13671.6 KEZ43140.1 - 0.0075 16.4 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KEZ43140.1 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KEZ43140.1 - 0.01 15.6 1.4 0.013 15.2 0.1 2.0 2 1 0 2 2 1 1 AAA domain TniB PF05621.11 KEZ43140.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 KEZ43140.1 - 0.013 15.2 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KEZ43140.1 - 0.024 14.4 0.2 0.055 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEZ43140.1 - 0.034 14.1 1.0 0.25 11.2 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KEZ43140.1 - 0.037 13.8 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KEZ43140.1 - 0.037 13.9 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 KEZ43140.1 - 0.04 13.3 1.1 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Viral_Hsp90 PF03225.14 KEZ43140.1 - 0.045 12.3 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_23 PF13476.6 KEZ43140.1 - 0.054 14.0 0.5 6.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KEZ43140.1 - 0.067 12.1 0.1 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.26 KEZ43140.1 - 0.081 12.6 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KEZ43140.1 - 0.084 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_25 PF13481.6 KEZ43140.1 - 0.1 12.2 1.5 0.21 11.1 0.3 2.1 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 KEZ43140.1 - 0.11 12.9 0.1 0.37 11.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEZ43140.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KEZ43140.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KEZ43140.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Y_phosphatase PF00102.27 KEZ43141.1 - 4.1e-45 154.2 0.0 8e-45 153.2 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KEZ43141.1 - 0.00044 20.4 0.0 0.0013 18.8 0.0 2.0 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KEZ43141.1 - 0.016 15.2 0.0 0.043 13.8 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 KEZ43141.1 - 0.023 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Lipase_GDSL_2 PF13472.6 KEZ43142.1 - 4e-09 37.1 0.0 6.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ43142.1 - 0.0011 19.0 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-MYND PF01753.18 KEZ43143.1 - 6.4e-09 35.8 14.8 6.4e-09 35.8 14.8 2.2 2 0 0 2 2 2 1 MYND finger SET PF00856.28 KEZ43143.1 - 1.2e-08 35.5 0.0 3.3e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 SET domain SWM_repeat PF13753.6 KEZ43143.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative flagellar system-associated repeat HIP1_clath_bdg PF16515.5 KEZ43144.1 - 0.00035 21.1 16.2 0.024 15.3 1.7 3.9 1 1 3 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF948 PF06103.11 KEZ43144.1 - 0.0011 19.2 3.9 0.13 12.6 1.5 3.2 1 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 KEZ43144.1 - 0.0011 19.5 17.6 0.99 10.1 1.6 5.2 3 1 3 6 6 6 1 SlyX HALZ PF02183.18 KEZ43144.1 - 0.0016 18.6 0.6 2.8 8.3 0.0 3.3 3 0 0 3 3 2 0 Homeobox associated leucine zipper Fez1 PF06818.15 KEZ43144.1 - 0.002 18.6 14.9 0.0052 17.3 13.4 2.3 1 1 0 1 1 1 1 Fez1 TolA_bind_tri PF16331.5 KEZ43144.1 - 0.0023 18.0 14.3 0.013 15.5 0.9 4.0 2 1 2 4 4 4 2 TolA binding protein trimerisation Trimer_CC PF08954.11 KEZ43144.1 - 0.0026 17.3 11.3 0.08 12.5 0.2 4.7 3 1 1 4 4 4 1 Trimerisation motif DivIC PF04977.15 KEZ43144.1 - 0.0031 17.3 0.4 0.0031 17.3 0.4 4.2 3 1 3 6 6 6 1 Septum formation initiator ERM PF00769.19 KEZ43144.1 - 0.0048 16.8 13.7 0.0048 16.8 13.7 1.9 1 1 1 2 2 2 1 Ezrin/radixin/moesin family LPP PF04728.13 KEZ43144.1 - 0.01 16.2 3.1 1.2 9.6 0.1 4.5 3 1 3 6 6 5 0 Lipoprotein leucine-zipper TMF_TATA_bd PF12325.8 KEZ43144.1 - 0.012 15.9 15.7 0.021 15.0 0.6 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KEZ43144.1 - 0.013 15.6 3.8 0.013 15.6 3.8 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc29 PF17082.5 KEZ43144.1 - 0.014 15.2 13.5 0.25 11.1 2.6 3.2 1 1 2 3 3 3 0 Spindle Pole Component 29 Fib_alpha PF08702.10 KEZ43144.1 - 0.016 15.4 11.1 0.64 10.2 2.0 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 KEZ43144.1 - 0.021 14.9 1.5 0.021 14.9 1.5 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 KEZ43144.1 - 0.024 15.0 10.4 2.6 8.5 0.7 4.8 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 KEZ43144.1 - 0.031 14.7 7.6 1.8 9.1 0.6 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 KEZ43144.1 - 0.041 13.5 15.1 0.049 13.2 2.9 2.8 1 1 2 3 3 3 0 Intermediate filament protein TRAF_BIRC3_bd PF16673.5 KEZ43144.1 - 0.069 12.9 1.6 0.15 11.8 0.2 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain CCDC-167 PF15188.6 KEZ43144.1 - 0.074 13.4 11.1 0.13 12.6 0.0 3.9 2 1 0 2 2 1 0 Coiled-coil domain-containing protein 167 DUF2383 PF09537.10 KEZ43144.1 - 0.079 13.3 1.1 3.3 8.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) AAA_13 PF13166.6 KEZ43144.1 - 0.082 11.5 10.3 0.029 13.0 6.4 2.0 1 1 0 2 2 2 0 AAA domain BLOC1_2 PF10046.9 KEZ43144.1 - 0.14 12.5 9.6 5.2 7.4 1.0 4.1 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GP120 PF00516.18 KEZ43144.1 - 0.2 10.2 0.0 0.33 9.5 0.0 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP120 DUF2746 PF10874.8 KEZ43144.1 - 0.21 12.0 2.8 0.97 9.9 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) DUF489 PF04356.12 KEZ43144.1 - 0.24 11.4 5.9 0.65 10.0 0.1 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF489) TPR_MLP1_2 PF07926.12 KEZ43144.1 - 0.26 11.4 13.2 0.081 13.0 1.0 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 KEZ43144.1 - 0.27 11.4 8.3 1.2 9.3 0.0 4.0 4 1 1 5 5 3 0 bZIP transcription factor GrpE PF01025.19 KEZ43144.1 - 0.28 10.8 10.9 2.2 7.9 0.2 3.9 1 1 2 3 3 3 0 GrpE FapA PF03961.13 KEZ43144.1 - 0.28 9.7 6.5 1.4 7.4 1.5 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prominin PF05478.11 KEZ43144.1 - 0.29 9.0 6.5 0.36 8.7 5.6 1.5 1 1 1 2 2 2 0 Prominin YlqD PF11068.8 KEZ43144.1 - 0.3 11.5 7.6 1.1 9.7 0.8 2.7 1 1 2 3 3 3 0 YlqD protein YabA PF06156.13 KEZ43144.1 - 0.32 11.7 11.7 1.8 9.2 1.1 4.0 1 1 2 3 3 3 0 Initiation control protein YabA GAS PF13851.6 KEZ43144.1 - 0.33 10.3 13.6 0.73 9.2 5.2 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 KEZ43144.1 - 0.34 10.6 20.6 2 8.1 16.4 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 KEZ43144.1 - 0.37 9.8 14.3 0.045 12.8 4.7 2.4 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 KEZ43144.1 - 0.42 10.8 5.6 0.21 11.8 1.5 2.6 3 0 0 3 3 1 0 Haemolysin XhlA Prefoldin_3 PF13758.6 KEZ43144.1 - 0.44 10.6 3.5 8.6 6.5 0.4 3.4 3 1 0 3 3 3 0 Prefoldin subunit DUF3584 PF12128.8 KEZ43144.1 - 0.45 8.0 13.4 0.63 7.5 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 KEZ43144.1 - 0.48 8.9 9.3 0.67 8.4 9.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Transcrip_act PF04949.13 KEZ43144.1 - 0.62 9.9 6.4 1.1 9.2 1.1 3.0 2 1 1 3 3 3 0 Transcriptional activator Spc7 PF08317.11 KEZ43144.1 - 0.64 8.8 15.5 0.054 12.4 2.4 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4795 PF16043.5 KEZ43144.1 - 0.72 9.4 11.8 1.7 8.2 11.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) USP8_interact PF08941.10 KEZ43144.1 - 0.73 9.6 5.0 5.1 6.9 0.5 2.7 1 1 1 3 3 2 0 USP8 interacting COG2 PF06148.11 KEZ43144.1 - 0.78 9.8 8.2 0.23 11.5 0.8 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 KEZ43144.1 - 0.79 10.2 15.9 8.7 6.9 0.6 4.2 4 1 0 4 4 4 0 Cell division protein ZapB TMPIT PF07851.13 KEZ43144.1 - 0.82 8.9 8.1 0.11 11.7 1.4 2.2 1 1 0 2 2 2 0 TMPIT-like protein EzrA PF06160.12 KEZ43144.1 - 0.86 7.7 10.0 0.16 10.2 0.5 2.4 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 KEZ43144.1 - 0.92 8.8 13.3 0.17 11.2 8.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PI3K_P85_iSH2 PF16454.5 KEZ43144.1 - 0.97 9.0 12.2 11 5.6 8.9 2.9 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain RPW8 PF05659.11 KEZ43144.1 - 1.1 8.9 3.7 9.2 6.0 0.2 3.0 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Hrs_helical PF12210.8 KEZ43144.1 - 1.4 9.5 11.6 0.048 14.2 1.9 2.8 2 1 1 3 3 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Mod_r PF07200.13 KEZ43144.1 - 1.6 8.8 12.8 0.77 9.8 2.6 3.3 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.8 KEZ43144.1 - 1.7 8.8 19.2 0.14 12.2 1.0 3.7 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KEZ43144.1 - 2 9.0 14.6 0.93 10.0 6.8 2.9 2 1 1 3 3 2 0 Apg6 coiled-coil region AATF-Che1 PF13339.6 KEZ43144.1 - 2.1 9.1 11.9 1.7 9.4 0.2 3.0 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor DUF4618 PF15397.6 KEZ43144.1 - 2.2 7.6 12.7 0.27 10.6 1.3 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) KxDL PF10241.9 KEZ43144.1 - 2.4 8.5 7.4 0.24 11.7 0.5 2.9 2 1 0 3 3 1 0 Uncharacterized conserved protein Macoilin PF09726.9 KEZ43144.1 - 2.4 6.6 12.0 4.2 5.8 12.0 1.5 1 1 0 1 1 1 0 Macoilin family TMF_DNA_bd PF12329.8 KEZ43144.1 - 3 7.9 13.9 3 7.9 0.6 3.6 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KEZ43144.1 - 3.8 7.6 12.9 2 8.5 1.6 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 KEZ43144.1 - 3.8 7.8 8.1 1.5 9.1 0.1 3.6 2 1 2 4 4 3 0 Domain of unknown function (DUF5082) APC_N_CC PF16689.5 KEZ43144.1 - 4.1 7.5 10.0 0.42 10.7 0.2 3.4 4 0 0 4 4 2 0 Coiled-coil N-terminus of APC, dimerisation domain Laminin_II PF06009.12 KEZ43144.1 - 4.8 7.2 10.7 0.7 9.9 2.2 2.9 1 1 3 4 4 4 0 Laminin Domain II zf-C4H2 PF10146.9 KEZ43144.1 - 5.1 7.3 13.5 1.8e+02 2.3 13.5 2.6 1 1 0 1 1 1 0 Zinc finger-containing protein Cnn_1N PF07989.11 KEZ43144.1 - 5.1 7.3 13.0 22 5.3 1.1 4.7 1 1 4 5 5 5 0 Centrosomin N-terminal motif 1 SOGA PF11365.8 KEZ43144.1 - 6.1 8.0 12.3 21 6.3 0.1 3.6 2 1 1 3 3 3 0 Protein SOGA Tup_N PF08581.10 KEZ43144.1 - 6.5 7.1 7.2 1.8 8.9 0.7 3.2 2 1 2 4 4 3 0 Tup N-terminal DUF4200 PF13863.6 KEZ43144.1 - 6.6 7.2 12.4 2.3 8.6 0.9 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FAM76 PF16046.5 KEZ43144.1 - 8.2 5.7 9.7 1.2 8.4 1.6 2.4 1 1 0 2 2 2 0 FAM76 protein DUF16 PF01519.16 KEZ43144.1 - 9.3 6.8 9.2 72 3.9 4.0 3.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF4201 PF13870.6 KEZ43144.1 - 9.5 5.9 14.7 3.1 7.5 1.8 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) LMBR1 PF04791.16 KEZ43144.1 - 9.9 4.9 7.4 7.3 5.4 5.9 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Seryl_tRNA_N PF02403.22 KEZ43144.1 - 9.9 6.4 13.1 1.8 8.8 0.6 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_1 PF00515.28 KEZ43145.1 - 1.4e-28 97.5 0.1 7.3e-07 28.7 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ43145.1 - 3.6e-26 89.1 2.8 1.2e-05 25.1 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ43145.1 - 2.6e-19 69.6 4.6 2.4e-05 24.9 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ43145.1 - 9.2e-19 66.9 2.5 2.4e-06 27.1 0.0 5.4 4 2 2 6 6 6 3 TPR repeat TPR_14 PF13428.6 KEZ43145.1 - 2.7e-17 62.0 8.1 6.7e-05 23.4 0.0 6.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ43145.1 - 4.7e-16 57.6 0.6 0.0042 17.2 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ43145.1 - 1.9e-15 57.1 3.1 0.00025 21.5 0.9 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ43145.1 - 7.7e-13 48.5 0.4 4.7e-05 23.6 0.0 4.5 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ43145.1 - 1.4e-12 47.1 1.2 0.021 15.2 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ43145.1 - 6.5e-12 44.6 1.7 0.38 10.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ43145.1 - 6.5e-10 39.0 0.6 0.046 13.9 0.6 3.8 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 KEZ43145.1 - 1e-09 38.6 0.3 0.012 15.9 0.2 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ43145.1 - 5.9e-09 36.0 3.7 0.35 11.6 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ43145.1 - 2.6e-06 26.8 0.7 0.011 14.9 0.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ43145.1 - 3.1e-05 24.1 0.7 0.069 13.4 0.0 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KEZ43145.1 - 0.012 15.4 4.0 6.1 6.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KEZ43145.1 - 0.013 15.5 0.0 5.3 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1641 PF07849.11 KEZ43145.1 - 0.11 12.3 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Coatomer_E PF04733.14 KEZ43145.1 - 0.11 11.8 0.1 4 6.7 0.0 3.0 3 1 1 4 4 4 0 Coatomer epsilon subunit HLH PF00010.26 KEZ43146.1 - 3.7e-12 46.0 1.7 3.7e-12 46.0 1.7 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Phage_GPO PF05929.11 KEZ43146.1 - 0.029 14.0 1.2 0.047 13.3 1.2 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4776 PF16003.5 KEZ43146.1 - 0.05 12.6 1.2 0.073 12.1 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF4674 PF15719.5 KEZ43146.1 - 0.092 12.8 2.4 0.18 11.8 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) RsbRD_N PF14361.6 KEZ43146.1 - 0.28 11.9 2.6 0.72 10.6 1.3 2.1 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF641 PF04859.12 KEZ43146.1 - 0.84 10.0 3.8 1.5 9.2 3.8 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HR1 PF02185.16 KEZ43146.1 - 1 9.5 5.4 0.32 11.1 0.9 2.2 2 0 0 2 2 2 0 Hr1 repeat TMEM52 PF14979.6 KEZ43146.1 - 1.2 9.1 3.1 19 5.2 0.3 2.7 2 0 0 2 2 2 0 Transmembrane 52 SlyX PF04102.12 KEZ43146.1 - 1.3 9.7 5.7 2.1 9.0 1.0 2.6 2 0 0 2 2 2 0 SlyX Tim17 PF02466.19 KEZ43147.1 - 0.0048 17.3 0.0 0.0079 16.6 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BPD_transp_2 PF02653.16 KEZ43147.1 - 0.14 11.3 0.7 0.22 10.7 0.7 1.3 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Ribosomal_S8e PF01201.22 KEZ43148.1 - 1.6e-44 151.4 2.4 2.5e-44 150.8 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L23eN PF03939.13 KEZ43148.1 - 0.0069 16.6 1.6 0.0069 16.6 1.6 2.8 3 0 0 3 3 3 1 Ribosomal protein L23, N-terminal domain AAA_11 PF13086.6 KEZ43148.1 - 0.13 12.0 3.9 0.17 11.6 3.9 1.1 1 0 0 1 1 1 0 AAA domain RIBIOP_C PF04950.12 KEZ43148.1 - 0.44 9.9 4.6 1.5 8.2 4.6 1.8 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Pkinase PF00069.25 KEZ43149.1 - 1.4e-44 152.5 0.0 2.1e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43149.1 - 9.6e-22 77.5 0.0 1.5e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ43149.1 - 3.9e-05 23.7 0.7 0.51 10.2 0.0 3.6 3 1 1 4 4 4 2 Phosphotransferase enzyme family PsaA_PsaB PF00223.19 KEZ43149.1 - 0.061 11.5 0.0 0.089 11.0 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Kinase-like PF14531.6 KEZ43149.1 - 0.061 12.6 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Ribosomal_60s PF00428.19 KEZ43150.1 - 1e-26 93.4 11.7 1.2e-26 93.2 11.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KEZ43150.1 - 0.019 15.3 0.4 0.029 14.7 0.0 1.4 2 0 0 2 2 2 0 EF-hand domain UBA_6 PF18039.1 KEZ43150.1 - 0.11 12.5 0.2 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 UBA-like domain DUF3824 PF12868.7 KEZ43150.1 - 0.39 11.4 3.2 0.52 11.0 3.2 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF2967 PF11179.8 KEZ43150.1 - 1.8 6.6 4.6 1.8 6.6 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Fungal_trans PF04082.18 KEZ43151.1 - 7.9e-09 34.9 0.9 1.2e-08 34.4 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Scytalone_dh PF02982.14 KEZ43152.1 - 2.7e-84 280.8 0.9 3.1e-84 280.6 0.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 KEZ43152.1 - 4.3e-08 33.3 1.1 5.9e-08 32.9 1.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain zf-C2H2_4 PF13894.6 KEZ43154.1 - 0.00027 21.5 6.5 0.016 16.0 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ43154.1 - 0.016 15.6 5.4 0.06 13.8 1.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type LRRFIP PF09738.9 KEZ43154.1 - 0.026 14.0 0.3 0.041 13.4 0.3 1.2 1 0 0 1 1 1 0 LRRFIP family CpXC PF14353.6 KEZ43154.1 - 0.031 14.3 3.2 0.069 13.2 3.2 1.6 1 0 0 1 1 1 0 CpXC protein Annexin PF00191.20 KEZ43155.1 - 5.7e-72 237.7 4.7 4.9e-21 74.6 0.3 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 KEZ43155.1 - 0.0008 19.2 0.3 2.6 7.9 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3574) Myb_DNA-bind_7 PF15963.5 KEZ43155.1 - 0.12 12.3 0.2 8 6.4 0.0 2.8 3 0 0 3 3 3 0 Myb DNA-binding like MFS_1 PF07690.16 KEZ43156.1 - 4e-31 108.2 40.2 7.7e-27 94.1 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ43156.1 - 8.8e-05 22.0 19.4 0.00048 19.5 19.4 1.9 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB V-ATPase_H_N PF03224.14 KEZ43157.1 - 1.6e-72 244.5 0.3 2.8e-72 243.7 0.3 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KEZ43157.1 - 9.7e-36 122.4 0.0 4e-35 120.4 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 KEZ43157.1 - 0.029 14.8 0.9 0.51 10.8 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats DUF3829 PF12889.7 KEZ43157.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF4690 PF15756.5 KEZ43158.1 - 0.12 12.9 2.2 0.44 11.2 0.3 2.7 3 0 0 3 3 3 0 Small Novel Rich in Cartilage DUF4834 PF16118.5 KEZ43158.1 - 0.48 11.4 1.5 4.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CYYR1 PF10873.8 KEZ43158.1 - 0.54 10.7 0.1 0.54 10.7 0.1 2.9 2 1 1 3 3 3 0 Cysteine and tyrosine-rich protein 1 Ribosomal_L6 PF00347.23 KEZ43159.1 - 8.3e-29 100.1 3.7 1e-13 51.7 0.3 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.15 KEZ43160.1 - 1.9e-131 437.1 1.2 2.2e-131 436.9 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KEZ43160.1 - 0.00077 19.5 0.1 0.35 10.9 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KEZ43160.1 - 0.0069 16.8 0.0 0.075 13.5 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 KEZ43160.1 - 0.068 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Nup160 PF11715.8 KEZ43161.1 - 6.3e-135 450.9 0.0 8e-135 450.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF816 PF05674.12 KEZ43161.1 - 0.06 13.3 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF816) Rad51 PF08423.11 KEZ43162.1 - 3.9e-127 422.8 0.0 4.9e-127 422.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KEZ43162.1 - 1.5e-08 34.4 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KEZ43162.1 - 1.4e-07 31.3 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KEZ43162.1 - 6e-06 25.8 0.0 1.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KEZ43162.1 - 0.00012 22.6 1.0 0.00037 21.0 0.2 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KEZ43162.1 - 0.035 13.4 0.1 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 KEZ43162.1 - 0.1 12.6 0.2 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 KEZ43162.1 - 0.13 11.3 0.1 0.65 9.1 0.0 1.9 2 0 0 2 2 2 0 PAXNEB protein AAA_24 PF13479.6 KEZ43162.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.26 KEZ43163.1 - 1.1e-29 103.2 0.4 2.7e-29 102.0 0.4 1.6 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 KEZ43164.1 - 4.1e-39 134.9 0.1 7.8e-37 127.4 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KEZ43164.1 - 1.5e-27 96.2 0.3 3.6e-27 95.0 0.3 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.21 KEZ43165.1 - 8.8e-20 71.3 14.8 1.2e-19 70.9 14.8 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEZ43165.1 - 0.011 15.9 0.0 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter YL1 PF05764.13 KEZ43166.1 - 0.0056 16.8 5.5 0.0056 16.8 5.5 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Pox_Ag35 PF03286.14 KEZ43166.1 - 0.054 13.3 5.8 0.11 12.3 5.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 KEZ43166.1 - 4.7 5.2 9.4 6.6 4.7 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi UBN_AB PF14075.6 KEZ43166.1 - 7.5 6.2 6.9 19 4.9 6.9 1.6 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Peptidase_S9 PF00326.21 KEZ43167.1 - 9.4e-53 178.8 0.0 1.4e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 KEZ43167.1 - 0.0001 22.1 0.1 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat AXE1 PF05448.12 KEZ43167.1 - 0.0021 16.8 0.0 0.0078 14.9 0.0 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) NuA4 PF09340.10 KEZ43168.1 - 7.9e-23 80.1 0.3 7.9e-23 80.1 0.3 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF601 PF04642.12 KEZ43168.1 - 0.046 13.2 2.7 0.08 12.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 PspB PF06667.12 KEZ43168.1 - 0.088 12.9 1.7 0.14 12.2 1.7 1.3 1 0 0 1 1 1 0 Phage shock protein B Mito_fiss_reg PF05308.11 KEZ43168.1 - 2 8.4 5.5 8.6 6.4 0.8 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Calreticulin PF00262.18 KEZ43169.1 - 6e-169 561.7 17.2 7.8e-169 561.3 17.2 1.1 1 0 0 1 1 1 1 Calreticulin family DUF842 PF05811.13 KEZ43170.1 - 0.29 10.8 7.3 2.7 7.7 0.6 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) AF-4 PF05110.13 KEZ43170.1 - 0.5 8.4 11.7 0.46 8.5 11.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4787 PF16029.5 KEZ43170.1 - 3.1 8.0 9.0 0.91 9.7 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4787) Dynamin_M PF01031.20 KEZ43171.1 - 1e-110 369.5 0.0 2.4e-110 368.3 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KEZ43171.1 - 6.9e-57 192.2 0.0 3e-56 190.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KEZ43171.1 - 2.5e-30 104.5 1.1 2.5e-30 104.5 1.1 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KEZ43171.1 - 2e-05 24.6 0.3 0.0005 20.1 0.3 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase CHCH PF06747.13 KEZ43172.1 - 0.00057 19.9 0.0 0.00098 19.2 0.0 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KEZ43172.1 - 0.0088 16.4 1.3 1.3 9.5 0.1 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KEZ43172.1 - 0.024 14.9 2.0 0.57 10.5 2.5 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KEZ43172.1 - 0.034 14.2 0.6 0.069 13.2 0.6 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 KEZ43172.1 - 0.13 12.5 0.1 16 5.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) LIM PF00412.22 KEZ43173.1 - 8.7e-09 35.5 6.4 8.7e-09 35.5 6.4 2.4 3 0 0 3 3 3 1 LIM domain DUF2321 PF10083.9 KEZ43173.1 - 0.003 17.2 0.4 0.003 17.2 0.4 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.6 KEZ43173.1 - 0.054 13.4 6.0 1.3 9.0 1.1 3.4 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.7 KEZ43173.1 - 0.1 12.6 8.0 0.23 11.5 7.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 KEZ43173.1 - 1.7 9.2 9.3 0.2 12.2 4.4 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-dskA_traR PF01258.17 KEZ43173.1 - 4.4 7.3 8.8 0.18 11.7 1.2 2.8 3 1 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Zn-ribbon_8 PF09723.10 KEZ43173.1 - 7 6.9 10.7 6.1 7.1 6.3 2.8 2 1 0 2 2 2 0 Zinc ribbon domain Nup84_Nup100 PF04121.13 KEZ43174.1 - 1.4e-138 463.1 0.0 1.9e-138 462.7 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Mod_r PF07200.13 KEZ43174.1 - 6.1e-28 97.8 1.7 1.3e-27 96.7 1.1 1.9 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein F-box PF00646.33 KEZ43175.1 - 7.2e-06 25.8 1.0 1.6e-05 24.6 1.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEZ43175.1 - 0.0026 17.6 0.3 0.013 15.4 0.4 2.2 2 0 0 2 2 2 1 F-box-like V-ATPase_C PF03223.15 KEZ43176.1 - 1.2e-93 314.5 0.2 8.4e-76 255.8 0.2 2.0 1 1 1 2 2 2 2 V-ATPase subunit C SHE3 PF17078.5 KEZ43176.1 - 0.048 13.4 1.9 0.085 12.6 1.6 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 TFIID_20kDa PF03847.13 KEZ43176.1 - 0.15 12.6 0.1 0.34 11.4 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A E1-E2_ATPase PF00122.20 KEZ43178.1 - 3.5e-34 117.9 24.6 3.5e-30 104.9 0.3 3.8 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEZ43178.1 - 3.6e-27 95.2 1.9 3.6e-27 95.2 1.9 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KEZ43178.1 - 4.3e-20 71.6 0.0 8.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ43178.1 - 6.1e-19 69.1 0.0 1.2e-14 55.1 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ43178.1 - 2e-11 43.4 0.0 4.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ43178.1 - 3.7e-06 26.9 0.4 0.00013 21.8 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 KEZ43179.1 - 2.6e-53 176.8 23.1 2.8e-09 37.5 0.5 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ43179.1 - 2.5e-09 37.3 0.0 0.0034 17.6 0.0 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ43179.1 - 0.00018 20.3 0.5 0.19 10.3 0.1 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 F-box-like PF12937.7 KEZ43179.1 - 0.0086 16.0 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.11 KEZ43179.1 - 0.11 11.3 0.0 2.4 6.8 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like NADH-u_ox-rdase PF10785.9 KEZ43180.1 - 2.6e-29 101.7 0.2 4.4e-29 101.0 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KEZ43180.1 - 2.1e-26 91.7 0.1 2.9e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 KEZ43181.1 - 1.3e-28 98.8 0.2 1.7e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 bZIP_2 PF07716.15 KEZ43182.1 - 9.4e-08 32.0 16.5 2.3e-07 30.8 16.5 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KEZ43182.1 - 0.00015 21.8 20.3 0.00052 20.1 20.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KEZ43182.1 - 0.0065 17.0 11.9 0.013 16.0 11.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor KIAA1430 PF13879.6 KEZ43182.1 - 0.29 11.9 6.7 0.16 12.7 2.2 2.5 1 1 1 2 2 2 0 KIAA1430 homologue SprA-related PF12118.8 KEZ43182.1 - 1.4 8.0 8.8 0.036 13.2 1.7 1.8 2 0 0 2 2 2 0 SprA-related family Snf7 PF03357.21 KEZ43183.1 - 9.8e-06 25.3 23.3 9.8e-06 25.3 23.3 1.5 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 KEZ43183.1 - 0.0012 18.7 8.2 0.0024 17.8 8.2 1.4 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ASL_C PF08328.11 KEZ43183.1 - 0.033 14.3 7.5 0.67 10.1 3.2 2.6 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminal Com_YlbF PF06133.11 KEZ43183.1 - 2.9 8.5 22.3 0.12 13.0 14.1 2.5 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DSHCT PF08148.12 KEZ43184.1 - 2.6e-52 176.8 0.5 6.6e-52 175.5 0.5 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Transket_pyr PF02779.24 KEZ43184.1 - 7e-45 152.9 0.0 1.5e-44 151.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Ski2_N PF17911.1 KEZ43184.1 - 6.1e-38 129.7 0.0 5.5e-37 126.6 0.0 2.3 2 0 0 2 2 2 1 Ski2 N-terminal region Transketolase_C PF02780.20 KEZ43184.1 - 1.7e-33 115.1 0.0 4.1e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain rRNA_proc-arch PF13234.6 KEZ43184.1 - 3.6e-20 73.0 0.0 6.1e-19 69.0 0.0 2.3 1 1 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KEZ43184.1 - 4.1e-17 62.5 0.0 1.5e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ43184.1 - 4.8e-06 26.9 0.0 1.5e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ43184.1 - 0.00014 21.9 0.1 0.00062 19.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1507 PF07408.11 KEZ43184.1 - 0.15 12.0 0.2 2 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1507) Sterol_MT_C PF08498.10 KEZ43185.1 - 1.2e-29 102.3 0.1 2.4e-29 101.4 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KEZ43185.1 - 1.4e-20 73.8 0.0 2.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ43185.1 - 1.2e-19 70.8 0.0 2.6e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43185.1 - 1.3e-18 67.2 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ43185.1 - 7.4e-12 45.4 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEZ43185.1 - 1.7e-11 43.9 0.1 2.5e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KEZ43185.1 - 1.8e-11 43.9 0.0 4.2e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KEZ43185.1 - 9.3e-11 42.4 0.0 5.6e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KEZ43185.1 - 5.8e-05 22.9 0.0 0.00014 21.6 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KEZ43185.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KEZ43185.1 - 0.00062 19.3 0.0 0.0017 17.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KEZ43185.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KEZ43185.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KEZ43185.1 - 0.013 15.5 0.9 0.027 14.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 KEZ43185.1 - 0.025 15.6 0.1 0.095 13.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_29 PF03141.16 KEZ43185.1 - 0.027 13.0 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.14 KEZ43185.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 KEZ43185.1 - 0.056 12.7 0.1 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 KEZ43185.1 - 0.08 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3222 PF11519.8 KEZ43185.1 - 0.096 12.9 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) RRM_1 PF00076.22 KEZ43186.1 - 7.2e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEZ43186.1 - 0.00068 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KEZ43186.1 - 0.00078 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KEZ43186.1 - 0.0082 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Complex1_LYR PF05347.15 KEZ43187.1 - 0.00047 20.2 1.0 0.0011 19.0 0.3 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEZ43187.1 - 0.038 14.7 0.2 0.051 14.3 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like RAC_head PF16717.5 KEZ43188.1 - 5.6e-29 101.0 2.1 5.6e-29 101.0 2.1 3.5 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 KEZ43188.1 - 1.1e-18 67.1 1.4 4.5e-18 65.1 1.4 2.2 1 0 0 1 1 1 1 DnaJ domain DUF1691 PF07950.11 KEZ43190.1 - 4.2e-36 123.9 6.4 1e-31 109.9 3.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.8 KEZ43191.1 - 1e-05 25.6 2.5 1.7e-05 25.0 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ43191.1 - 0.0007 19.9 1.0 0.0012 19.2 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KEZ43191.1 - 0.034 14.6 0.9 0.06 13.8 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ43191.1 - 0.084 13.8 0.3 0.18 12.8 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KEZ43191.1 - 0.099 13.0 0.7 0.15 12.4 0.7 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GRIP PF01465.20 KEZ43192.1 - 1.1e-15 57.2 0.1 2.7e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 GRIP domain APG6_N PF17675.1 KEZ43192.1 - 0.00079 20.0 4.7 0.00079 20.0 4.7 10.2 2 2 7 11 11 10 4 Apg6 coiled-coil region Phage_GP20 PF06810.11 KEZ43192.1 - 0.0044 16.8 5.4 0.0044 16.8 5.4 9.8 3 2 6 10 10 10 4 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 KEZ43192.1 - 0.0085 16.3 24.8 0.0085 16.3 24.8 9.4 3 2 4 7 7 6 2 Tropomyosin like PKcGMP_CC PF16808.5 KEZ43192.1 - 0.031 14.1 0.2 0.031 14.1 0.2 10.7 12 1 1 13 13 12 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3800 PF12686.7 KEZ43192.1 - 0.032 14.8 0.0 13 6.5 0.0 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) EFG_C PF00679.24 KEZ43192.1 - 0.15 12.1 1.4 1.9 8.6 0.0 3.5 3 0 0 3 3 3 0 Elongation factor G C-terminus GAS PF13851.6 KEZ43192.1 - 0.33 10.3 160.7 0.37 10.1 19.7 9.6 4 4 5 9 9 9 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KEZ43192.1 - 0.45 9.3 156.4 0.32 9.8 17.2 7.8 3 2 4 7 7 7 0 Spc7 kinetochore protein HOOK PF05622.12 KEZ43192.1 - 0.49 8.5 138.2 0.045 11.9 20.0 5.8 3 1 1 4 4 3 0 HOOK protein MscS_porin PF12795.7 KEZ43192.1 - 2.8 7.4 143.2 0.032 13.8 27.1 7.0 3 2 3 6 6 6 0 Mechanosensitive ion channel porin domain Pox_A_type_inc PF04508.12 KEZ43192.1 - 4.8 7.2 30.6 1.8 8.6 1.4 7.5 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat CENP-F_leu_zip PF10473.9 KEZ43192.1 - 9.9 6.2 172.7 0.31 11.1 13.3 9.5 3 2 6 9 9 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zinc_ribbon_10 PF10058.9 KEZ43193.1 - 2e-18 65.8 0.2 3.4e-18 65.1 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein CCDC-167 PF15188.6 KEZ43193.1 - 0.16 12.3 0.0 0.65 10.4 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 zf-RanBP PF00641.18 KEZ43193.1 - 0.3 10.4 2.9 0.22 10.9 0.4 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others AAA_lid_6 PF17866.1 KEZ43193.1 - 0.86 9.8 2.9 1.8 8.8 0.5 2.2 2 0 0 2 2 2 0 AAA lid domain AIF-MLS PF14962.6 KEZ43193.1 - 1.3 8.9 4.0 0.35 10.8 0.1 1.8 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Pkinase PF00069.25 KEZ43194.1 - 1.6e-41 142.4 0.2 1.5e-22 80.2 0.2 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43194.1 - 3.7e-14 52.7 0.4 1.5e-09 37.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.11 KEZ43195.1 - 3.4e-10 39.8 0.0 7.8e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Brr6_like_C_C PF10104.9 KEZ43196.1 - 1e-29 103.0 1.2 1.3e-29 102.7 1.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.18 KEZ43197.1 - 7.2e-21 74.4 0.2 1.2e-20 73.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ43197.1 - 1.2e-07 31.7 13.1 2.2e-07 30.9 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex16 PF08610.10 KEZ43198.1 - 1.9e-136 454.5 0.3 2.1e-136 454.3 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) CHAD PF05235.14 KEZ43198.1 - 0.038 14.0 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 CHAD domain Bestrophin PF01062.21 KEZ43198.1 - 0.34 10.2 2.3 0.59 9.5 1.9 1.5 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel zf-C2H2_4 PF13894.6 KEZ43199.1 - 0.0063 17.2 16.4 0.045 14.6 1.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KEZ43199.1 - 0.028 14.8 5.2 0.88 10.0 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SPX PF03105.19 KEZ43199.1 - 0.49 10.3 8.2 0.82 9.5 8.2 1.3 1 0 0 1 1 1 0 SPX domain zf-C2H2 PF00096.26 KEZ43199.1 - 4.2 8.0 15.7 0.32 11.5 1.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type HLH PF00010.26 KEZ43200.1 - 1.3e-18 66.7 0.2 2.2e-18 65.9 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 KEZ43200.1 - 0.0082 15.8 6.5 0.012 15.2 6.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DGF-1_C PF11040.8 KEZ43200.1 - 0.026 14.5 2.7 0.063 13.3 2.7 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SNF2_N PF00176.23 KEZ43201.1 - 4.3e-60 203.3 0.1 6.6e-60 202.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KEZ43201.1 - 1.4e-08 34.9 0.1 2.3e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ43201.1 - 3e-07 30.4 0.0 6.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ43201.1 - 0.005 17.2 0.0 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 KEZ43201.1 - 0.028 14.1 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase NACHT PF05729.12 KEZ43202.1 - 2.4e-11 43.9 0.0 5.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ43202.1 - 7.2e-09 36.0 0.0 3.5e-08 33.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ43202.1 - 2.2e-07 31.4 0.3 1.2e-05 25.8 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.14 KEZ43202.1 - 4.6e-05 22.8 0.1 0.045 13.0 0.1 2.7 2 0 0 2 2 2 2 KAP family P-loop domain AAA PF00004.29 KEZ43202.1 - 0.0014 19.0 1.8 0.013 16.0 0.0 3.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Goodbye PF17109.5 KEZ43202.1 - 0.0019 18.6 2.1 0.0034 17.8 0.1 2.5 3 0 0 3 3 2 1 fungal STAND N-terminal Goodbye domain NB-ARC PF00931.22 KEZ43202.1 - 0.0062 15.8 0.2 0.018 14.2 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 KEZ43202.1 - 0.0087 15.6 0.1 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KEZ43202.1 - 0.0088 16.1 0.1 0.13 12.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KEZ43202.1 - 0.015 15.1 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 KEZ43202.1 - 0.022 14.7 0.0 0.076 12.9 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 KEZ43202.1 - 0.025 14.7 0.0 0.077 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ43202.1 - 0.043 14.4 0.0 0.15 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ43202.1 - 0.073 12.3 0.0 0.23 10.7 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 KEZ43202.1 - 0.076 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 KEZ43202.1 - 0.088 12.2 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KEZ43202.1 - 0.09 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KEZ43202.1 - 0.13 12.7 0.1 0.5 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 KEZ43202.1 - 0.15 12.1 6.9 2.8 8.0 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain RecG_N PF17190.4 KEZ43202.1 - 0.77 10.5 4.0 2.7 8.8 0.2 3.3 3 0 0 3 3 2 0 RecG N-terminal helical domain Retrotrans_gag PF03732.17 KEZ43202.1 - 6.9 7.0 7.8 1.9 8.8 2.9 2.6 3 0 0 3 3 2 0 Retrotransposon gag protein AMP-binding PF00501.28 KEZ43203.1 - 1.4e-74 251.3 0.0 1.8e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ43203.1 - 8.1e-13 49.2 0.5 1.7e-12 48.1 0.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KEZ43204.1 - 3.9e-05 22.8 0.5 0.13 11.2 0.0 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain APH PF01636.23 KEZ43205.1 - 1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ43205.1 - 0.0043 16.7 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase WD40 PF00400.32 KEZ43206.1 - 1.6e-18 66.7 3.4 7.1e-05 23.5 0.4 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KEZ43206.1 - 0.024 13.3 0.1 0.12 11.0 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ43206.1 - 0.089 11.7 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 KEZ43207.1 - 4.4e-11 43.1 0.5 0.25 12.3 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat SRR1 PF07985.12 KEZ43208.1 - 6.6e-09 35.7 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 SRR1 Ribosomal_60s PF00428.19 KEZ43208.1 - 0.078 13.6 6.9 0.18 12.4 6.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PUL PF08324.11 KEZ43209.1 - 1.6e-55 188.3 0.0 2.2e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KEZ43209.1 - 1.4e-44 150.9 0.2 2.5e-44 150.2 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KEZ43209.1 - 1.4e-31 108.0 10.6 1.9e-05 25.3 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KEZ43209.1 - 2.2e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain AAA_12 PF13087.6 KEZ43211.1 - 2e-33 115.7 0.0 4.2e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ43211.1 - 4.2e-21 75.9 0.0 3.6e-20 72.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ43211.1 - 5.8e-10 39.2 0.1 7.2e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KEZ43211.1 - 2.8e-09 37.5 0.0 3e-07 30.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KEZ43211.1 - 5.8e-05 22.9 0.0 0.0059 16.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KEZ43211.1 - 0.0093 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KEZ43211.1 - 0.015 14.8 0.0 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 KEZ43211.1 - 0.019 14.5 0.0 10 5.5 0.0 3.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain NAD_binding_10 PF13460.6 KEZ43212.1 - 6.2e-16 58.8 0.0 7.1e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ43212.1 - 4.2e-13 49.4 0.0 4.8e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEZ43212.1 - 2.2e-06 27.4 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEZ43212.1 - 1.7e-05 25.1 0.1 2.2e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 KEZ43212.1 - 0.00011 22.2 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ43212.1 - 0.00074 18.7 0.0 0.0012 18.0 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 KEZ43212.1 - 0.0035 17.9 0.1 0.0063 17.1 0.1 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent LpxI_N PF17930.1 KEZ43212.1 - 0.0044 16.9 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 LpxI N-terminal domain DapB_N PF01113.20 KEZ43212.1 - 0.009 16.1 0.2 0.013 15.6 0.2 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 KEZ43212.1 - 0.014 14.9 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 KEZ43212.1 - 0.022 13.8 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KEZ43212.1 - 0.025 13.7 0.0 0.11 11.6 0.0 1.7 1 1 1 2 2 2 0 RmlD substrate binding domain Gp_dh_N PF00044.24 KEZ43212.1 - 0.027 14.8 0.2 0.088 13.2 0.1 1.8 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ43212.1 - 0.03 14.4 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DXP_reductoisom PF02670.16 KEZ43212.1 - 0.052 14.3 0.4 0.43 11.3 0.2 2.0 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.24 KEZ43212.1 - 0.082 13.3 0.1 0.13 12.7 0.1 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.7 KEZ43213.1 - 1.8e-53 179.1 0.1 4.1e-13 49.7 0.0 6.1 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ43213.1 - 6e-47 157.1 3.6 3.3e-09 36.8 0.0 7.7 4 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43213.1 - 8.2e-41 136.7 6.7 0.00011 22.4 0.0 10.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KEZ43213.1 - 2.1e-40 136.6 6.3 9.5e-09 35.6 0.0 10.5 5 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43213.1 - 4.6e-39 128.0 0.5 0.00021 21.5 0.0 10.4 9 0 0 9 9 9 7 Ankyrin repeat NACHT PF05729.12 KEZ43213.1 - 8.9e-12 45.2 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 KEZ43213.1 - 7.1e-07 28.8 0.4 1.4e-06 27.8 0.4 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KEZ43213.1 - 4.2e-05 24.0 1.5 0.0012 19.2 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KEZ43213.1 - 0.0015 18.8 0.1 0.012 15.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 KEZ43213.1 - 0.0054 17.2 0.0 0.02 15.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEZ43213.1 - 0.024 14.7 0.1 0.68 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 KEZ43213.1 - 0.64 10.1 3.9 1.3 9.1 1.5 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHQ_synthase PF01761.20 KEZ43214.1 - 1.2e-56 191.8 0.0 1.8e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 KEZ43214.1 - 5.6e-08 32.8 0.0 8.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Couple_hipA PF13657.6 KEZ43214.1 - 0.18 12.5 0.0 0.47 11.1 0.0 1.7 1 0 0 1 1 1 0 HipA N-terminal domain ADH_N PF08240.12 KEZ43215.1 - 5.6e-23 80.9 0.6 1.2e-22 79.8 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ43215.1 - 5.5e-18 65.2 0.0 9.6e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ43215.1 - 2.8e-09 36.8 0.0 3.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEZ43215.1 - 9.7e-07 29.9 0.0 2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KEZ43215.1 - 0.0021 17.4 0.1 0.0031 16.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KEZ43215.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ank_2 PF12796.7 KEZ43217.1 - 8.4e-25 87.2 0.0 6.8e-11 42.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43217.1 - 2.2e-21 75.9 0.8 1.7e-08 34.8 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43217.1 - 1.3e-19 69.6 4.5 9e-05 22.7 0.1 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KEZ43217.1 - 5.3e-18 63.3 0.3 0.0011 19.3 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KEZ43217.1 - 2e-17 63.0 0.9 1.4e-06 28.5 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) TPR_12 PF13424.6 KEZ43217.1 - 0.071 13.4 0.5 0.41 11.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SesA PF17107.5 KEZ43217.1 - 0.36 11.0 5.2 10 6.4 0.4 3.9 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sugar_tr PF00083.24 KEZ43218.1 - 9e-56 189.6 26.2 4.7e-31 108.1 11.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43218.1 - 4.9e-07 29.0 36.7 4.9e-07 29.0 36.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DCB PF16213.5 KEZ43218.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Sulfatase PF00884.23 KEZ43219.1 - 3.6e-63 213.8 0.9 4.9e-63 213.4 0.9 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEZ43219.1 - 0.0052 16.4 0.5 1 8.8 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KEZ43219.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Zn_clus PF00172.18 KEZ43220.1 - 1.2e-07 31.7 13.5 2.1e-07 30.9 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEZ43220.1 - 6.3e-06 25.2 0.4 8e-06 24.9 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGAP1 PF07819.13 KEZ43222.1 - 1.2e-07 31.7 0.0 3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEZ43222.1 - 1e-05 26.2 0.0 4.4e-05 24.2 0.0 2.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ANAPC4_WD40 PF12894.7 KEZ43222.1 - 0.00056 20.2 0.0 6.9 7.0 0.0 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cutinase PF01083.22 KEZ43222.1 - 0.008 16.2 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Cutinase NACHT PF05729.12 KEZ43222.1 - 0.023 14.6 0.0 0.075 13.0 0.0 1.9 1 1 0 1 1 1 0 NACHT domain DUF676 PF05057.14 KEZ43222.1 - 0.032 13.7 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_22 PF13401.6 KEZ43222.1 - 0.039 14.2 0.1 1.5 9.1 0.0 3.1 2 1 0 3 3 3 0 AAA domain LCAT PF02450.15 KEZ43222.1 - 0.15 11.2 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Arg_repressor_C PF02863.18 KEZ43222.1 - 0.55 10.1 2.8 3 7.8 0.2 2.5 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Fructosamin_kin PF03881.14 KEZ43223.1 - 2.8e-15 56.3 0.0 3.5e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase Glyco_hydro_61 PF03443.14 KEZ43224.1 - 8.2e-39 133.7 0.0 1.2e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAD-oxidase_C PF02913.19 KEZ43226.1 - 1.9e-59 201.3 0.1 2.9e-59 200.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ43226.1 - 4.5e-40 136.6 0.0 9.7e-40 135.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ANF_receptor PF01094.28 KEZ43226.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region SepSecS PF05889.13 KEZ43226.1 - 0.1 11.2 0.2 0.25 10.0 0.1 1.6 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Peptidase_S15 PF02129.18 KEZ43227.1 - 6.7e-33 114.4 0.8 2.2e-26 93.1 1.9 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KEZ43227.1 - 2.8e-20 73.2 0.0 5.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 KEZ43227.1 - 0.015 14.8 0.3 0.024 14.1 0.3 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family HET PF06985.11 KEZ43228.1 - 8.7e-14 52.1 4.1 2.2e-10 41.1 0.3 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box PF00646.33 KEZ43229.1 - 0.079 12.9 0.6 0.22 11.5 0.2 2.0 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 KEZ43230.1 - 2.5e-144 470.2 17.8 2.4e-17 63.3 0.0 13.7 2 2 10 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43230.1 - 1.9e-111 363.2 18.2 9.7e-10 38.8 0.1 18.6 9 4 13 22 22 22 21 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43230.1 - 1.6e-104 329.1 18.1 0.00018 21.7 0.0 28.5 29 0 0 29 29 29 21 Ankyrin repeat Ank_5 PF13857.6 KEZ43230.1 - 1.1e-93 306.0 33.5 2.3e-10 40.5 0.1 17.8 8 5 10 19 19 19 17 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43230.1 - 4.5e-93 302.0 39.6 1.2e-05 25.6 0.0 27.2 28 1 0 28 28 28 22 Ankyrin repeat HET PF06985.11 KEZ43230.1 - 2.9e-29 102.3 0.0 7.3e-29 101.0 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VWA_3_C PF18571.1 KEZ43230.1 - 0.33 10.9 2.6 1.7e+02 2.2 0.0 5.1 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Methyltransf_23 PF13489.6 KEZ43231.1 - 2.2e-19 69.9 0.0 3.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ43231.1 - 7.4e-11 42.6 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43231.1 - 1.5e-07 31.3 0.0 1.6e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ43231.1 - 6.4e-07 29.9 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ43231.1 - 8.1e-06 26.5 0.0 3.9e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KEZ43231.1 - 0.0022 17.7 0.0 0.0059 16.3 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KEZ43231.1 - 0.0029 17.0 0.0 0.022 14.0 0.0 2.2 3 0 0 3 3 3 1 O-methyltransferase domain MTS PF05175.14 KEZ43231.1 - 0.027 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KEZ43231.1 - 0.097 12.0 0.0 1.2 8.4 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KEZ43231.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KEZ43231.1 - 0.19 11.2 0.0 0.55 9.7 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.20 KEZ43231.1 - 0.25 10.4 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase E1-E2_ATPase PF00122.20 KEZ43232.1 - 1.7e-32 112.4 0.1 1.7e-32 112.4 0.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ43232.1 - 1.8e-16 61.1 0.2 5.2e-16 59.6 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ43232.1 - 4.7e-10 39.0 0.0 9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 KEZ43232.1 - 2.7e-08 33.7 16.9 1.9e-07 31.0 9.6 3.4 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KEZ43232.1 - 1.2e-07 31.7 0.0 4.2e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Leucyl-specific PF14795.6 KEZ43232.1 - 0.014 15.5 0.1 0.036 14.1 0.1 1.7 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain MFS_1 PF07690.16 KEZ43233.1 - 5.1e-31 107.9 48.6 2.1e-29 102.6 48.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43233.1 - 6.1e-10 38.5 9.8 6.1e-10 38.5 9.8 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KEZ43233.1 - 2.8 6.1 14.4 24 3.0 14.3 2.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Hydrolase_4 PF12146.8 KEZ43235.1 - 0.00068 19.0 0.0 0.00099 18.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 KEZ43235.1 - 0.051 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KEZ43235.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KEZ43235.1 - 0.17 12.4 0.0 0.24 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short_C2 PF13561.6 KEZ43236.1 - 6.8e-57 192.7 0.1 7.9e-57 192.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43236.1 - 5.6e-46 156.5 0.0 6.8e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ43236.1 - 1.8e-11 44.3 0.0 2.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ43236.1 - 0.0032 16.9 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S8 PF00082.22 KEZ43238.1 - 1.9e-08 33.9 0.6 2.3e-07 30.4 0.6 2.3 1 1 0 1 1 1 1 Subtilase family zf-RING_2 PF13639.6 KEZ43241.1 - 0.00015 22.0 13.0 0.00026 21.2 13.0 1.4 1 0 0 1 1 1 1 Ring finger domain APH PF01636.23 KEZ43241.1 - 0.00017 21.6 0.0 0.00052 20.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FANCL_C PF11793.8 KEZ43241.1 - 0.00055 20.0 9.3 0.001 19.2 9.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KEZ43241.1 - 0.0082 16.2 4.7 0.015 15.3 4.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KEZ43241.1 - 0.76 10.1 10.7 1.4 9.2 10.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KEZ43241.1 - 4.1 7.3 11.6 6.9 6.5 11.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KEZ43241.1 - 9.7 6.3 12.7 16 5.6 12.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Na_H_Exchanger PF00999.21 KEZ43242.1 - 1.8e-53 181.8 47.3 2.7e-53 181.1 47.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Aldo_ket_red PF00248.21 KEZ43243.1 - 5e-62 209.8 0.0 5.7e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RAG2 PF03089.14 KEZ43243.1 - 0.076 12.0 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Recombination activating protein 2 Egh16-like PF11327.8 KEZ43244.1 - 9.6e-08 32.7 0.0 1.1e-07 32.5 0.0 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor MFS_1 PF07690.16 KEZ43245.1 - 5.2e-18 65.1 20.0 9.6e-17 60.9 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 KEZ43245.1 - 3.1 7.4 10.3 6.3 6.4 2.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) FAD_binding_4 PF01565.23 KEZ43246.1 - 4.9e-27 94.4 0.0 7.1e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ43246.1 - 2.7e-09 37.0 0.1 4.3e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain HNH_2 PF13391.6 KEZ43249.1 - 6.9e-05 22.9 0.0 0.00041 20.4 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease CTP_synth_N PF06418.14 KEZ43250.1 - 1.7e-109 365.2 0.3 2.5e-109 364.7 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KEZ43250.1 - 9.4e-59 198.4 0.0 1.4e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KEZ43250.1 - 4.4e-06 26.6 0.0 1.3e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 KEZ43250.1 - 0.0033 17.5 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 KEZ43250.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Transket_pyr PF02779.24 KEZ43250.1 - 0.072 12.8 0.0 0.3 10.7 0.1 1.9 2 0 0 2 2 2 0 Transketolase, pyrimidine binding domain ArsA_ATPase PF02374.15 KEZ43250.1 - 0.1 11.7 0.4 0.17 11.1 0.4 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase HET PF06985.11 KEZ43251.1 - 3.9e-38 131.1 0.1 6.4e-35 120.7 0.0 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 KEZ43252.1 - 4.7e-31 108.3 0.0 6.2e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 KEZ43252.1 - 5.3e-09 35.9 0.1 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KEZ43252.1 - 9.8e-08 31.6 0.9 9.2e-06 25.1 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43252.1 - 1.9e-06 28.0 0.2 9.5e-06 25.8 0.2 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ43252.1 - 1.8e-05 24.2 0.9 0.0016 17.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ43252.1 - 7.6e-05 21.6 0.5 0.0015 17.3 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KEZ43252.1 - 0.00011 21.4 0.9 0.02 14.0 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 KEZ43252.1 - 0.00015 21.5 0.8 0.043 13.4 1.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ43252.1 - 0.00032 21.2 0.6 0.023 15.2 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ43252.1 - 0.00059 19.1 0.2 0.002 17.4 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KEZ43252.1 - 0.0011 18.1 1.9 0.002 17.3 1.3 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KEZ43252.1 - 0.006 15.5 0.2 0.0095 14.8 0.1 1.4 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KEZ43252.1 - 0.02 14.9 0.4 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KEZ43252.1 - 0.05 13.0 0.1 0.12 11.7 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KEZ43252.1 - 0.23 10.5 2.9 0.16 11.0 0.9 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A HeLo PF14479.6 KEZ43253.1 - 6.6e-37 127.4 0.8 1.3e-36 126.4 0.8 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation UQ_con PF00179.26 KEZ43253.1 - 0.052 13.2 0.0 0.43 10.2 0.0 2.2 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Ank_2 PF12796.7 KEZ43254.1 - 2e-40 137.2 1.4 2.4e-13 50.5 0.0 7.8 5 2 3 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43254.1 - 4.9e-34 116.3 0.1 2.3e-05 24.9 0.0 9.0 5 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43254.1 - 5.4e-27 90.9 0.8 0.0017 18.7 0.0 11.5 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 KEZ43254.1 - 2.1e-20 72.5 0.2 0.0017 18.6 0.0 8.3 5 2 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43254.1 - 7.3e-19 67.3 5.5 0.044 14.3 0.0 10.3 10 0 0 10 10 10 5 Ankyrin repeat Clr5 PF14420.6 KEZ43254.1 - 1.3e-08 34.9 0.1 3.1e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 Clr5 domain Dicty_CAR PF05462.11 KEZ43255.1 - 2.5e-07 30.1 6.7 2.5e-07 30.1 6.7 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KEZ43255.1 - 0.00017 21.0 0.1 0.00025 20.5 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KEZ43255.1 - 0.37 10.5 10.7 0.021 14.6 5.6 1.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 NmrA PF05368.13 KEZ43256.1 - 7.3e-18 65.0 0.0 1.5e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ43256.1 - 1.2e-16 61.1 0.3 2.2e-16 60.3 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEZ43256.1 - 8.2e-06 26.1 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 KEZ43256.1 - 0.00051 20.6 0.2 0.0012 19.4 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 KEZ43256.1 - 0.0017 18.8 0.1 0.0042 17.5 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KEZ43256.1 - 0.0031 17.0 0.1 0.0054 16.2 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ43256.1 - 0.0066 16.4 0.5 0.019 14.9 0.5 1.8 1 1 0 1 1 1 1 KR domain Pallilysin PF18663.1 KEZ43256.1 - 0.031 14.3 0.4 0.8 9.7 0.2 2.2 2 0 0 2 2 2 0 Pallilysin beta barrel domain DapB_N PF01113.20 KEZ43256.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 KEZ43256.1 - 0.11 13.2 0.2 1.3 9.8 0.1 2.4 2 1 0 2 2 2 0 CoA binding domain ApbA PF02558.16 KEZ43256.1 - 0.21 11.2 0.3 0.47 10.1 0.3 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 KEZ43258.1 - 5.9e-21 74.8 0.0 8.3e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43258.1 - 4.4e-10 39.5 0.0 6.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43258.1 - 4e-09 36.7 0.3 6.3e-09 36.0 0.1 1.4 2 0 0 2 2 2 1 KR domain YAcAr PF10686.9 KEZ43258.1 - 0.025 14.5 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family AAA_16 PF13191.6 KEZ43260.1 - 0.17 12.3 0.8 0.46 10.8 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain adh_short PF00106.25 KEZ43261.1 - 6.1e-15 55.2 0.0 1.3e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43261.1 - 2.1e-13 50.4 0.0 4.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AAA PF00004.29 KEZ43261.1 - 4e-08 33.7 3.0 2e-05 25.0 3.0 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Tho1_MOS11_C PF18592.1 KEZ43261.1 - 0.11 12.3 1.0 0.4 10.5 0.2 2.3 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain FMO-like PF00743.19 KEZ43262.1 - 1.5e-46 158.9 0.0 5.6e-44 150.5 0.0 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pkinase PF00069.25 KEZ43262.1 - 4.7e-14 52.4 0.0 6.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pyr_redox_3 PF13738.6 KEZ43262.1 - 7.9e-13 48.3 0.0 3.5e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ43262.1 - 2.9e-08 33.3 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ43262.1 - 1.5e-07 30.9 0.0 2e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEZ43262.1 - 0.023 14.7 0.0 0.71 9.9 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3638 PF12340.8 KEZ43263.1 - 2.3e-96 321.5 0.7 7.6e-96 319.8 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KEZ43263.1 - 6.3e-16 57.5 0.4 1.5e-15 56.3 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Ank_2 PF12796.7 KEZ43264.1 - 6.7e-32 109.9 0.0 6e-12 46.0 0.0 6.0 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43264.1 - 1.3e-26 92.6 2.9 2e-06 28.2 0.0 7.7 4 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ43264.1 - 2.9e-24 84.8 6.0 4.1e-07 30.2 0.0 6.4 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43264.1 - 2.2e-22 76.7 4.4 0.0002 21.5 0.0 8.2 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 KEZ43264.1 - 8e-21 73.5 6.3 0.0011 19.3 0.1 8.4 8 1 0 8 8 8 5 Ankyrin repeat CDC37_M PF08565.11 KEZ43265.1 - 1.1e-26 93.1 0.1 2.2e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KEZ43265.1 - 2.5e-24 85.3 0.7 2.5e-24 85.3 0.7 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain CDC37_N PF03234.14 KEZ43265.1 - 8.4e-11 42.9 0.3 5.4e-09 37.0 0.0 2.7 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding ScsC_N PF18312.1 KEZ43265.1 - 0.015 15.1 0.8 0.038 13.8 0.0 2.1 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain CPT PF07931.12 KEZ43265.1 - 0.069 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MFS_1 PF07690.16 KEZ43266.1 - 9e-17 61.0 47.3 9e-17 61.0 47.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43266.1 - 0.0018 17.2 7.7 0.0018 17.2 7.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Copper-bind PF00127.20 KEZ43267.1 - 0.036 14.5 0.1 0.062 13.8 0.1 1.3 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Exonuc_VII_L PF02601.15 KEZ43268.1 - 0.56 9.7 16.0 0.79 9.2 16.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.16 KEZ43268.1 - 4.5 7.2 6.8 6.9 6.7 6.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Borrelia_P83 PF05262.11 KEZ43268.1 - 9.8 4.5 24.2 14 4.0 24.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_hydro_7 PF00840.20 KEZ43269.1 - 9.4e-181 601.3 2.6 1.1e-180 601.1 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CFEM PF05730.11 KEZ43270.1 - 1.1e-07 31.9 9.0 1.5e-07 31.4 9.0 1.2 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.9 KEZ43271.1 - 0.46 9.6 18.8 0.64 9.1 18.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Lipase_GDSL_2 PF13472.6 KEZ43272.1 - 1.3e-14 54.9 0.2 1.8e-14 54.5 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ43272.1 - 2.7e-07 30.8 0.0 4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KEZ43272.1 - 0.0097 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KEZ43272.1 - 0.11 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 OSK domain CxC4 PF18717.1 KEZ43274.1 - 0.064 13.1 2.2 2 8.3 0.1 2.2 2 0 0 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases MFS_1 PF07690.16 KEZ43275.1 - 5.4e-30 104.5 24.6 8.8e-30 103.8 24.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1065 PF06358.11 KEZ43275.1 - 0.18 11.8 0.5 0.48 10.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) MFS_1 PF07690.16 KEZ43276.1 - 3e-22 79.0 27.6 4.7e-14 52.1 9.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PGPGW PF09656.10 KEZ43276.1 - 9.2 5.9 9.8 0.17 11.4 1.7 2.4 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) DUF5325 PF17259.2 KEZ43276.1 - 9.8 6.1 7.3 0.77 9.7 1.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Aldolase_II PF00596.21 KEZ43277.1 - 6.1e-44 150.2 0.1 7.6e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ank_2 PF12796.7 KEZ43278.1 - 3.3e-51 171.8 0.0 6.2e-13 49.1 0.0 6.2 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43278.1 - 8.5e-42 141.0 0.1 9.7e-07 29.2 0.1 8.9 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43278.1 - 3.7e-35 118.8 8.6 0.0021 18.4 0.0 11.2 13 0 0 13 13 13 9 Ankyrin repeat Ank_3 PF13606.6 KEZ43278.1 - 1.1e-33 111.4 5.2 0.02 15.4 0.0 12.2 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 KEZ43278.1 - 4.1e-33 113.0 7.1 1.2e-08 35.0 0.2 8.6 6 2 3 9 9 9 6 Ankyrin repeats (many copies) A_thal_3526 PF09713.10 KEZ43278.1 - 0.096 12.9 0.0 13 6.1 0.0 3.8 4 0 0 4 4 4 0 Plant protein 1589 of unknown function (A_thal_3526) F-box-like PF12937.7 KEZ43278.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like Arm-DNA-bind_3 PF13356.6 KEZ43278.1 - 0.12 12.7 0.0 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 Arm DNA-binding domain HSP70 PF00012.20 KEZ43279.1 - 2.1e-05 22.9 0.1 0.00028 19.2 0.0 2.4 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ43279.1 - 0.16 10.8 0.0 8.4 5.1 0.0 3.1 4 0 0 4 4 4 0 MreB/Mbl protein WcbI PF18588.1 KEZ43280.1 - 0.064 12.9 0.9 0.17 11.5 0.9 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI Rx_N PF18052.1 KEZ43280.1 - 1.9 8.8 9.5 1 9.7 0.2 3.0 3 0 0 3 3 3 0 Rx N-terminal domain Aldo_ket_red PF00248.21 KEZ43281.1 - 1.7e-67 227.7 0.0 2.1e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KEZ43282.1 - 3e-21 75.7 13.2 3e-21 75.7 13.2 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KEZ43284.1 - 2e-18 66.5 0.0 2.8e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 KEZ43284.1 - 0.022 15.1 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 KEZ43284.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family FAD_binding_4 PF01565.23 KEZ43286.1 - 3.3e-22 78.7 0.3 2e-21 76.2 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain PDEase_II PF02112.15 KEZ43286.1 - 0.18 10.9 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II AA_permease_2 PF13520.6 KEZ43287.1 - 1.1e-84 284.8 29.2 1.3e-84 284.6 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ43287.1 - 4.4e-14 51.9 28.8 9.2e-14 50.9 28.8 1.7 1 1 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 KEZ43287.1 - 0.095 12.9 0.0 2 8.6 0.0 3.1 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Fungal_trans PF04082.18 KEZ43289.1 - 0.00029 20.0 0.1 0.00049 19.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PMBR PF09373.10 KEZ43289.1 - 0.081 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 Pseudomurein-binding repeat Mito_carr PF00153.27 KEZ43290.1 - 9.7e-42 140.8 0.5 1.5e-20 72.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KEZ43290.1 - 8.3e-12 45.4 0.3 3.3e-08 33.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KEZ43290.1 - 8.1e-11 41.0 0.0 0.0016 18.2 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KEZ43290.1 - 1.5e-10 39.8 0.0 4.1e-06 25.9 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 KEZ43290.1 - 7.9e-09 34.6 0.0 2.7e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KEZ43290.1 - 5.2e-06 26.2 0.0 0.0001 22.0 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 KEZ43290.1 - 0.0013 19.0 0.0 0.043 14.1 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 KEZ43290.1 - 0.041 13.8 0.1 14 5.7 0.1 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KEZ43290.1 - 0.098 12.9 0.2 0.27 11.5 0.1 1.7 2 0 0 2 2 2 0 Dockerin type I domain HET PF06985.11 KEZ43291.1 - 1.1e-38 132.9 0.0 1.8e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KEZ43292.1 - 4.9e-13 48.7 47.4 4e-07 29.3 20.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ43292.1 - 1.5e-06 27.0 14.4 1.5e-06 27.0 14.4 2.1 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) NACHT PF05729.12 KEZ43293.1 - 7.1e-07 29.3 0.3 3e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ43293.1 - 5.1e-06 26.8 0.0 0.0034 17.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.14 KEZ43293.1 - 0.4 9.9 0.0 0.4 9.9 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_23 PF13476.6 KEZ43293.1 - 0.49 10.9 1.3 8.4 6.8 3.4 1.9 2 0 0 2 2 2 0 AAA domain P5CR_dimer PF14748.6 KEZ43294.1 - 1.2e-34 118.6 1.3 2.1e-34 117.9 0.4 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KEZ43294.1 - 2.8e-16 59.9 0.3 8e-16 58.4 0.3 1.8 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KEZ43294.1 - 0.023 14.7 0.1 0.063 13.3 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IFT20 PF14931.6 KEZ43294.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 YiaAB PF05360.14 KEZ43295.1 - 0.024 14.9 2.9 0.13 12.5 1.4 2.4 2 0 0 2 2 2 0 yiaA/B two helix domain Lipase_GDSL_2 PF13472.6 KEZ43296.1 - 2.4e-10 41.1 0.2 7.9e-10 39.4 0.1 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ43296.1 - 0.0024 17.9 0.0 0.0042 17.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Clr5 PF14420.6 KEZ43297.1 - 8.1e-06 26.0 0.7 1.3e-05 25.3 0.7 1.3 1 0 0 1 1 1 1 Clr5 domain TilS PF09179.11 KEZ43297.1 - 0.096 13.2 0.4 0.14 12.7 0.4 1.2 1 0 0 1 1 1 0 TilS substrate binding domain AAA_16 PF13191.6 KEZ43298.1 - 0.037 14.4 0.1 0.091 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KEZ43298.1 - 0.043 14.2 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ43298.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF346 PF03984.13 KEZ43301.1 - 0.04 13.7 21.7 1 9.1 1.0 6.4 6 1 0 6 6 6 0 Repeat of unknown function (DUF346) Cu_amine_oxid PF01179.20 KEZ43302.1 - 1.1e-104 350.6 1.6 7.5e-83 278.7 0.9 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KEZ43302.1 - 1.2e-06 28.6 0.0 2.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_N PF08403.10 KEZ43303.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal Serglycin PF04360.12 KEZ43303.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Serglycin Pkinase PF00069.25 KEZ43305.1 - 8.8e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KEZ43305.1 - 0.00068 19.6 0.4 0.0018 18.2 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEZ43305.1 - 0.011 15.1 0.0 0.062 12.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LrgB PF04172.16 KEZ43306.1 - 3e-44 151.1 14.5 9.7e-44 149.4 10.2 2.3 2 0 0 2 2 2 2 LrgB-like family FAD_binding_3 PF01494.19 KEZ43308.1 - 1.3e-19 70.7 0.1 2.1e-19 70.0 0.1 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ43308.1 - 5.5e-08 32.8 0.1 9.2e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ43308.1 - 1.4e-07 31.1 0.2 2.7e-07 30.1 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43308.1 - 1.4e-07 31.6 0.2 4e-07 30.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ43308.1 - 8.7e-07 28.4 1.1 1.3e-06 27.8 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KEZ43308.1 - 0.00014 22.4 0.5 0.00034 21.1 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ43308.1 - 0.00057 19.2 0.1 0.00091 18.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family ADC PF06314.11 KEZ43308.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) AlaDh_PNT_C PF01262.21 KEZ43308.1 - 0.00077 18.8 0.2 0.002 17.5 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KEZ43308.1 - 0.00082 18.2 0.3 0.0012 17.6 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ43308.1 - 0.003 16.8 0.2 0.0045 16.3 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ43308.1 - 0.0041 16.0 0.3 0.0058 15.5 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase MCRA PF06100.11 KEZ43308.1 - 0.0053 15.6 0.0 0.0078 15.0 0.0 1.2 1 0 0 1 1 1 1 MCRA family Lycopene_cycl PF05834.12 KEZ43308.1 - 0.0059 15.7 0.5 0.076 12.0 0.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KEZ43308.1 - 0.0066 15.8 0.1 0.4 9.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KEZ43308.1 - 0.0067 15.8 0.2 0.011 15.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ43308.1 - 0.012 14.8 0.3 0.016 14.3 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 KEZ43308.1 - 0.092 12.4 0.4 0.15 11.7 0.4 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KEZ43308.1 - 0.14 12.1 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KEZ43309.1 - 7.5e-05 21.9 0.0 9.6e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp_protease_2 PF13650.6 KEZ43310.1 - 1.9e-06 28.4 0.0 3.3e-05 24.4 0.0 2.2 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KEZ43310.1 - 8.9e-05 23.0 0.0 0.014 16.0 0.0 2.3 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KEZ43310.1 - 0.0048 16.7 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Aspartyl protease 4HBT_3 PF13622.6 KEZ43311.1 - 3.5e-46 158.5 0.0 4.1e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.25 KEZ43312.1 - 2.8e-27 95.7 0.0 2.4e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43312.1 - 8.9e-11 41.6 0.0 1e-05 25.0 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase MFS_1 PF07690.16 KEZ43313.1 - 1.6e-33 116.1 39.3 2.6e-33 115.4 39.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldedh PF00171.22 KEZ43314.1 - 1.7e-14 53.2 0.0 2.7e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF815 PF05673.13 KEZ43314.1 - 0.054 12.6 0.1 0.091 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FAA_hydrolase PF01557.18 KEZ43316.1 - 1.8e-54 184.7 0.0 2.3e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KEZ43316.1 - 2.6e-17 62.9 0.0 1e-16 61.0 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal ADC PF06314.11 KEZ43317.1 - 1.6e-12 47.6 0.0 6.1e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.19 KEZ43317.1 - 4.8e-12 45.8 0.0 7.3e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain PepX_C PF08530.10 KEZ43318.1 - 1.4e-45 156.0 0.1 2.1e-45 155.4 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KEZ43318.1 - 9.3e-41 140.2 0.5 1.3e-40 139.7 0.5 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KEZ43318.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LigB PF02900.18 KEZ43319.1 - 4e-16 58.9 0.1 2e-15 56.6 0.0 2.0 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NACHT PF05729.12 KEZ43319.1 - 2.6e-10 40.5 0.0 6.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 KEZ43319.1 - 1.7e-05 24.5 15.2 0.0082 16.0 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ43319.1 - 0.00012 22.5 0.0 0.00061 20.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain TPR_8 PF13181.6 KEZ43319.1 - 0.00025 21.0 11.7 0.11 12.7 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ43319.1 - 0.00026 21.2 19.8 0.25 11.7 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ43319.1 - 0.0013 18.6 9.9 1.9 8.7 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.6 KEZ43319.1 - 0.012 15.8 0.0 0.048 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KEZ43319.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TPR_1 PF00515.28 KEZ43319.1 - 0.15 11.9 0.0 0.15 11.9 0.0 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat Mg_chelatase PF01078.21 KEZ43319.1 - 0.17 11.3 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEZ43319.1 - 0.17 12.2 0.0 0.58 10.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase TPR_14 PF13428.6 KEZ43319.1 - 0.33 11.9 35.5 1.3 10.0 0.0 9.6 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ43319.1 - 0.59 9.9 17.7 3.5 7.4 0.0 6.4 9 0 0 9 9 9 0 TPR repeat TPR_17 PF13431.6 KEZ43319.1 - 2.7 8.5 8.2 24 5.6 0.0 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KEZ43320.1 - 8.6e-08 31.5 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.18 KEZ43321.1 - 6.4e-23 81.2 0.1 1.5e-22 80.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KEZ43321.1 - 0.018 15.7 0.0 0.052 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SesA PF17107.5 KEZ43322.1 - 0.054 13.7 1.1 0.24 11.6 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Methyltransf_23 PF13489.6 KEZ43323.1 - 3.5e-23 82.2 0.0 5.9e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ43323.1 - 4.3e-12 46.6 0.0 1.2e-11 45.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43323.1 - 1.2e-08 34.9 0.0 3.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ43323.1 - 1.3e-08 35.3 0.0 2.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ43323.1 - 1.3e-07 32.2 0.0 8.8e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KEZ43323.1 - 5e-05 23.5 0.0 0.00012 22.2 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ43323.1 - 0.0014 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ43323.1 - 0.0091 15.3 0.0 0.045 13.0 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KEZ43323.1 - 0.05 13.1 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KEZ43323.1 - 0.054 13.2 0.0 0.83 9.4 0.0 2.5 2 1 1 3 3 3 0 Lysine methyltransferase GidB PF02527.15 KEZ43323.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cation_efflux PF01545.21 KEZ43324.1 - 1.6e-14 54.1 8.0 2e-14 53.8 8.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KEZ43324.1 - 7.4e-08 32.4 1.6 1.9e-07 31.1 1.6 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter 4HBT_2 PF13279.6 KEZ43325.1 - 1.1e-20 74.3 0.2 1.7e-20 73.8 0.2 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Endonuc_subdom PF09062.10 KEZ43325.1 - 0.12 13.2 0.2 0.33 11.8 0.1 1.7 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain Lactonase PF10282.9 KEZ43326.1 - 1e-25 90.7 0.0 1.4e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 KEZ43326.1 - 0.021 14.8 0.9 3.5 7.7 0.0 2.7 2 1 0 2 2 2 0 WD40-like Beta Propeller Repeat RTA1 PF04479.13 KEZ43328.1 - 7.3e-71 238.0 8.7 7.3e-71 238.0 8.7 1.3 2 0 0 2 2 2 1 RTA1 like protein p450 PF00067.22 KEZ43330.1 - 4.6e-69 233.3 0.0 5.4e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glucosaminidase PF01832.20 KEZ43331.1 - 0.026 15.0 0.1 0.048 14.2 0.1 1.5 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase TMEM132D_C PF15706.5 KEZ43331.1 - 0.069 12.9 2.0 0.19 11.5 2.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PulG PF11773.8 KEZ43331.1 - 0.39 10.6 1.8 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin GMC_oxred_N PF00732.19 KEZ43332.1 - 6.5e-47 160.3 0.0 8.6e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ43332.1 - 6.9e-31 107.7 0.0 1.3e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ43332.1 - 1.4e-05 24.4 0.0 0.043 12.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KEZ43332.1 - 0.0037 16.4 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ43332.1 - 0.016 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KEZ43332.1 - 0.028 14.7 0.1 0.16 12.2 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEZ43332.1 - 0.034 13.0 0.2 0.049 12.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 KEZ43332.1 - 0.042 13.1 0.0 0.093 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ43332.1 - 0.064 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ43332.1 - 0.075 12.3 0.2 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ43332.1 - 0.087 12.4 1.3 0.19 11.3 0.6 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase ArsB PF02040.15 KEZ43333.1 - 8e-16 58.4 15.5 4e-12 46.2 5.1 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.16 KEZ43333.1 - 5.9e-15 55.2 0.1 1.4e-14 54.0 0.1 1.7 1 1 0 1 1 1 1 Citrate transporter Roughex PF06020.11 KEZ43333.1 - 0.0084 15.3 2.7 0.0084 15.3 2.7 1.6 1 1 1 2 2 2 1 Drosophila roughex protein Sgf11 PF08209.11 KEZ43334.1 - 0.59 9.7 5.7 5.4 6.7 0.1 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Cyclin_C PF02984.19 KEZ43335.1 - 0.056 13.5 0.2 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain 4HBT_2 PF13279.6 KEZ43336.1 - 2.2e-05 24.9 0.0 3.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily LPD24 PF18839.1 KEZ43336.1 - 0.12 12.6 0.1 0.43 10.9 0.1 1.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 COesterase PF00135.28 KEZ43337.1 - 4.1e-73 247.0 0.0 5.3e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ43337.1 - 0.00084 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.11 KEZ43338.1 - 1.8e-28 99.7 0.0 2.9e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMN_dh PF01070.18 KEZ43339.1 - 9.3e-41 140.0 0.0 1.2e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEZ43339.1 - 1.2e-23 83.0 0.2 2.9e-23 81.8 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Ribonuc_L-PSP PF01042.21 KEZ43340.1 - 8.5e-29 100.0 0.0 1e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aminotran_1_2 PF00155.21 KEZ43341.1 - 3e-34 118.8 0.0 3.7e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KEZ43341.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III Peptidase_S10 PF00450.22 KEZ43342.1 - 4.9e-68 230.5 0.0 2.2e-67 228.3 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 KEZ43343.1 - 3.8e-72 244.0 0.0 4.4e-72 243.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KEZ43343.1 - 1.2e-05 26.1 0.2 0.18 12.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ43343.1 - 0.013 14.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 KEZ43344.1 - 1.9e-09 37.5 8.4 3.3e-09 36.7 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KEZ43345.1 - 6.9e-143 477.5 56.2 7.9e-143 477.3 56.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S10 PF00450.22 KEZ43345.1 - 0.042 13.3 0.1 0.064 12.7 0.1 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase DUF2937 PF11157.8 KEZ43345.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Pro_racemase PF05544.11 KEZ43346.1 - 1.9e-61 208.0 0.0 2.3e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 KEZ43346.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein MFS_1 PF07690.16 KEZ43347.1 - 8.4e-17 61.1 19.2 8.4e-17 61.1 19.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily LrgA PF03788.14 KEZ43347.1 - 0.076 13.0 0.1 0.076 13.0 0.1 3.1 3 0 0 3 3 3 0 LrgA family ABC_tran PF00005.27 KEZ43348.1 - 6.4e-42 143.3 0.1 1.1e-24 87.5 0.0 3.3 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEZ43348.1 - 2.8e-32 112.5 29.6 2.5e-17 63.4 12.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KEZ43348.1 - 7.3e-13 49.0 1.9 0.0088 15.9 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ43348.1 - 1.5e-07 32.0 0.6 0.0001 22.7 0.2 2.7 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KEZ43348.1 - 3.8e-07 29.8 0.0 0.18 11.2 0.7 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ43348.1 - 7.3e-06 25.6 1.6 0.033 13.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ43348.1 - 1.9e-05 24.6 0.0 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KEZ43348.1 - 2.8e-05 24.1 0.9 0.057 13.5 0.1 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KEZ43348.1 - 3.1e-05 24.3 1.1 0.34 11.2 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KEZ43348.1 - 9.1e-05 23.0 0.6 0.04 14.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEZ43348.1 - 0.00066 19.3 0.2 0.3 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KEZ43348.1 - 0.0012 17.9 0.3 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KEZ43348.1 - 0.0099 15.2 0.9 0.51 9.6 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin DUP PF00674.18 KEZ43348.1 - 0.021 14.9 0.3 0.078 13.1 0.3 1.9 1 0 0 1 1 1 0 DUP family AAA_33 PF13671.6 KEZ43348.1 - 0.03 14.5 0.0 1 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KEZ43348.1 - 0.038 14.1 0.6 1 9.4 0.2 2.4 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 KEZ43348.1 - 0.066 12.9 1.4 1.7 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 KEZ43348.1 - 0.074 13.5 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 KEZ43348.1 - 0.096 12.4 0.0 5.9 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 KEZ43348.1 - 0.1 11.6 0.9 9.5 5.1 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 KEZ43348.1 - 0.12 12.0 0.2 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEZ43348.1 - 0.14 11.9 1.1 15 5.3 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KEZ43348.1 - 0.17 11.4 0.4 6.4 6.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KEZ43348.1 - 0.24 11.6 1.8 1.8 8.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 KEZ43348.1 - 1.4 8.8 3.7 9.8 6.1 0.1 2.8 3 0 0 3 3 3 0 NTPase Amidohydro_1 PF01979.20 KEZ43349.1 - 1.1e-11 44.7 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ43349.1 - 1.5e-08 34.5 0.0 3.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase family SCP1201-deam PF14428.6 KEZ43349.1 - 0.00055 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 SCP1.201-like deaminase Peptidase_S10 PF00450.22 KEZ43350.1 - 2.5e-76 257.8 0.0 1.1e-73 249.1 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_3_C PF01915.22 KEZ43352.1 - 8.6e-44 149.9 0.0 1.5e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ43352.1 - 6.5e-41 140.7 0.0 9.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ43352.1 - 6.6e-20 71.0 0.1 1.3e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.18 KEZ43353.1 - 7.2e-09 35.6 6.3 1.4e-08 34.7 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ43353.1 - 2.3e-06 26.8 0.0 4.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1631 PF07793.11 KEZ43353.1 - 0.23 9.8 1.1 0.32 9.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) FAM217 PF15344.6 KEZ43353.1 - 5.3 6.9 12.5 9.7 6.0 0.0 3.9 3 1 1 4 4 4 0 FAM217 family Sulfatase PF00884.23 KEZ43354.1 - 3.7e-75 253.2 0.0 4.5e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 KEZ43354.1 - 1.3e-05 25.9 0.1 0.00033 21.4 0.1 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 KEZ43354.1 - 0.0091 14.7 0.0 0.02 13.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KEZ43354.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KEZ43354.1 - 0.029 14.0 0.4 4.2 6.9 0.1 2.3 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KEZ43354.1 - 0.098 12.6 0.2 0.26 11.3 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function Sugar_tr PF00083.24 KEZ43355.1 - 5.9e-80 269.3 19.9 6.7e-80 269.2 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43355.1 - 9.8e-16 57.6 19.7 9.8e-16 57.6 19.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Cupin_2 PF07883.11 KEZ43356.1 - 1.2e-20 73.0 1.1 6.4e-19 67.4 0.3 2.4 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 KEZ43356.1 - 3.8e-05 23.6 0.1 6.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KEZ43356.1 - 3.9e-05 23.3 0.0 0.036 13.7 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.12 KEZ43356.1 - 0.0027 17.3 0.8 0.045 13.4 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF861) ARD PF03079.14 KEZ43356.1 - 0.2 11.9 0.1 0.37 11.0 0.1 1.4 1 0 0 1 1 1 0 ARD/ARD' family Fungal_trans PF04082.18 KEZ43357.1 - 6.2e-22 77.9 0.2 9e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_3 PF01764.25 KEZ43358.1 - 1.1e-22 80.4 0.0 2e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Anemone_cytotox PF06369.12 KEZ43359.1 - 0.00034 20.3 0.1 0.0004 20.1 0.1 1.2 1 0 0 1 1 1 1 Sea anemone cytotoxic protein Kinesin PF00225.23 KEZ43360.1 - 5.6e-59 199.7 0.0 7.4e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ43360.1 - 4.9e-10 39.5 0.0 8.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Aminotran_4 PF01063.19 KEZ43360.1 - 0.03 14.2 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Amino-transferase class IV AAA_22 PF13401.6 KEZ43360.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KEZ43361.1 - 7.3e-35 120.5 38.6 1e-34 120.0 35.2 2.0 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ43361.1 - 1.4e-05 24.1 0.2 3.8e-05 22.7 0.3 1.7 1 1 0 1 1 1 1 MFS_1 like family p450 PF00067.22 KEZ43362.1 - 2.5e-30 105.6 0.0 3.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEZ43363.1 - 4.3e-42 144.3 48.9 6.2e-42 143.8 48.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ43363.1 - 1.8e-16 59.7 16.2 1.8e-16 59.7 16.2 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEZ43363.1 - 1.6e-11 43.7 28.0 9.6e-11 41.2 14.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pox_I5 PF04713.12 KEZ43363.1 - 0.67 10.0 5.6 0.34 11.0 2.3 2.3 2 0 0 2 2 2 0 Poxvirus protein I5 adh_short PF00106.25 KEZ43364.1 - 6.6e-22 77.9 0.0 4.8e-18 65.3 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43364.1 - 6.6e-14 52.0 0.1 4.7e-12 46.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43364.1 - 4.3e-07 30.0 0.0 6.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ43364.1 - 0.0016 17.9 0.1 0.0027 17.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ43364.1 - 0.0029 17.0 0.0 0.0082 15.6 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEZ43364.1 - 0.057 12.6 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KEZ43364.1 - 0.092 12.7 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase adh_short PF00106.25 KEZ43365.1 - 8e-21 74.4 0.0 1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43365.1 - 1.5e-12 47.6 0.0 1.9e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43365.1 - 4.6e-07 29.9 0.0 7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 KEZ43365.1 - 0.095 12.6 0.0 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family ketoacyl-synt PF00109.26 KEZ43366.1 - 7.5e-76 255.1 0.0 1.6e-75 253.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 KEZ43366.1 - 1.8e-74 250.8 0.1 5.8e-74 249.2 0.0 1.9 3 0 0 3 3 3 1 AMP-binding enzyme Condensation PF00668.20 KEZ43366.1 - 5.7e-68 229.7 0.0 8.4e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KEZ43366.1 - 4e-56 190.4 0.0 7.8e-56 189.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KEZ43366.1 - 6e-49 166.4 0.0 2.3e-48 164.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KEZ43366.1 - 2.6e-42 145.5 0.0 4.3e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KEZ43366.1 - 3.1e-36 124.9 0.0 2.5e-35 121.9 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KEZ43366.1 - 1.3e-28 99.4 0.0 2.8e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KEZ43366.1 - 6.6e-20 71.7 0.0 1.7e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KEZ43366.1 - 6.5e-15 55.2 3.9 1.9e-08 34.5 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KEZ43366.1 - 1.2e-14 54.4 0.0 3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KEZ43366.1 - 2.9e-14 53.5 0.0 7.5e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KEZ43366.1 - 3.7e-13 50.0 0.0 1.3e-12 48.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KEZ43366.1 - 1.1e-12 47.9 0.0 5.5e-10 39.1 0.0 2.9 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KEZ43366.1 - 1.5e-11 44.8 0.0 4.6e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ43366.1 - 5e-11 42.7 0.0 1.4e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KEZ43366.1 - 6.2e-10 38.9 0.0 3.4e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 KEZ43366.1 - 8e-07 28.6 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEZ43366.1 - 1.6e-06 28.0 0.0 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase Thiolase_N PF00108.23 KEZ43366.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NodS PF05401.11 KEZ43366.1 - 0.0026 17.4 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) 3Beta_HSD PF01073.19 KEZ43366.1 - 0.003 16.6 0.0 0.0073 15.3 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SAT PF16073.5 KEZ43366.1 - 0.021 14.6 0.2 0.12 12.0 0.2 2.1 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 KEZ43366.1 - 0.042 13.7 1.9 0.38 10.6 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding_C PF13193.6 KEZ43366.1 - 0.058 14.4 0.1 0.18 12.8 0.1 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Toprim PF01751.22 KEZ43366.1 - 0.18 12.1 0.0 0.71 10.1 0.0 2.0 2 0 0 2 2 1 0 Toprim domain ADH_zinc_N PF00107.26 KEZ43368.1 - 0.00014 21.8 0.1 0.00053 20.0 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ43368.1 - 0.0096 15.8 0.0 0.034 14.0 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KEZ43368.1 - 0.11 13.6 0.0 0.21 12.6 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase p450 PF00067.22 KEZ43369.1 - 2.6e-13 49.5 0.0 3.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KEZ43370.1 - 0.00021 21.1 0.0 0.00091 19.1 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ43370.1 - 0.014 15.3 0.2 0.054 13.5 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase p450 PF00067.22 KEZ43371.1 - 1.9e-67 228.0 0.0 2.5e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.21 KEZ43371.1 - 6.7e-54 183.1 0.0 9.6e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Herpes_HEPA PF03324.14 KEZ43371.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein Epimerase PF01370.21 KEZ43372.1 - 2.8e-12 46.6 0.2 1.3e-11 44.4 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ43372.1 - 1e-11 44.9 0.4 1.4e-11 44.4 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KEZ43372.1 - 3.2e-11 42.8 0.0 5.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEZ43372.1 - 1.5e-10 41.3 0.2 2.1e-10 40.8 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEZ43372.1 - 1e-07 31.4 0.0 6.7e-06 25.5 0.0 2.4 1 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KEZ43372.1 - 0.00013 21.5 0.2 0.00025 20.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KEZ43372.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEZ43372.1 - 0.042 13.2 0.1 0.08 12.3 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase FAD_binding_4 PF01565.23 KEZ43373.1 - 1.8e-19 69.8 0.6 2.3e-14 53.3 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.12 KEZ43373.1 - 3.5e-06 27.0 0.1 9.2e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KEZ43374.1 - 2.5e-34 118.8 0.0 3.2e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KEZ43375.1 - 6.9e-69 232.2 0.1 1.6e-68 231.0 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KEZ43375.1 - 1e-35 122.3 0.1 2e-35 121.4 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEZ43375.1 - 2.2e-30 106.3 0.0 3.6e-26 92.4 0.0 2.3 2 0 0 2 2 2 2 Acyl transferase domain PP-binding PF00550.25 KEZ43375.1 - 4.8e-21 74.9 2.4 4.2e-09 36.6 1.4 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KEZ43375.1 - 5.8e-21 75.0 0.0 1.1e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase HTH_51 PF18558.1 KEZ43375.1 - 1.3e-20 73.1 0.0 5.3e-20 71.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 KEZ43375.1 - 1.1e-13 51.8 0.0 2.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KEZ43375.1 - 1.3e-13 51.2 2.3 4.2e-10 39.8 0.2 3.3 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 KEZ43375.1 - 2.1e-09 38.0 0.0 5.9e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ43375.1 - 1.5e-08 34.7 0.0 6.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43375.1 - 5.5e-08 32.7 0.0 4.9e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ43375.1 - 6e-08 33.2 0.0 1.6e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 KEZ43375.1 - 3.8e-07 29.8 0.0 5.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ubie_methyltran PF01209.18 KEZ43375.1 - 3.5e-05 23.3 0.0 9.6e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KEZ43375.1 - 6.9e-05 22.3 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KEZ43375.1 - 0.00026 21.4 0.0 0.00094 19.6 0.0 1.9 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_16 PF10294.9 KEZ43375.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Hydrolase_4 PF12146.8 KEZ43375.1 - 0.037 13.3 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_33 PF10017.9 KEZ43375.1 - 0.094 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_28 PF02636.17 KEZ43375.1 - 0.22 11.1 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ACP_syn_III PF08545.10 KEZ43375.1 - 0.33 10.8 2.4 0.57 10.1 0.7 2.4 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ABC2_membrane PF01061.24 KEZ43377.1 - 1.7e-77 259.6 52.7 3.5e-41 140.9 27.0 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ43377.1 - 7.7e-41 139.8 0.1 3.6e-21 76.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEZ43377.1 - 3e-21 75.1 0.0 9.5e-21 73.5 0.0 1.9 1 0 0 1 1 1 1 CDR ABC transporter ABC_trans_N PF14510.6 KEZ43377.1 - 2.3e-07 31.4 0.0 7.2e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KEZ43377.1 - 1.8e-06 28.5 0.2 0.058 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KEZ43377.1 - 2.7e-06 28.0 0.1 0.0011 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KEZ43377.1 - 4e-06 26.8 0.2 0.00034 20.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KEZ43377.1 - 0.00021 21.2 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KEZ43377.1 - 0.0003 21.1 0.3 0.0092 16.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KEZ43377.1 - 0.00035 20.2 0.2 0.57 10.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ43377.1 - 0.00041 20.6 0.3 0.51 10.6 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KEZ43377.1 - 0.00051 20.2 0.2 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEZ43377.1 - 0.00096 19.2 1.3 0.18 11.9 0.3 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 KEZ43377.1 - 0.0027 17.3 0.2 0.41 10.2 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KEZ43377.1 - 0.011 15.4 0.8 2.3 7.9 0.3 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 KEZ43377.1 - 0.023 14.3 0.8 1.2 8.7 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEZ43377.1 - 0.035 14.0 0.3 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 KEZ43377.1 - 0.066 13.1 0.0 10 6.0 0.0 3.3 3 0 0 3 3 3 0 NTPase Thymidylate_kin PF02223.17 KEZ43377.1 - 0.07 12.8 0.0 4.4 6.9 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Zeta_toxin PF06414.12 KEZ43377.1 - 0.11 11.7 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 KEZ43377.1 - 0.14 11.9 0.3 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 KEZ43377.1 - 0.16 11.3 0.2 17 4.6 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 KEZ43377.1 - 0.19 11.7 0.1 25 4.7 0.1 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_13 PF13166.6 KEZ43377.1 - 0.32 9.6 0.3 3.1 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 KEZ43377.1 - 2.6 7.0 39.9 0.056 12.5 11.3 2.9 2 1 1 3 3 3 0 ABC-2 family transporter protein NMT1 PF09084.11 KEZ43378.1 - 1.4e-78 263.8 0.0 1.8e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KEZ43378.1 - 3.2e-05 23.7 0.1 0.73 9.5 0.0 3.7 3 1 1 4 4 4 2 NMT1-like family PBP_like PF12727.7 KEZ43378.1 - 0.038 13.1 0.0 0.086 12.0 0.0 1.6 1 1 1 2 2 2 0 PBP superfamily domain Phosphonate-bd PF12974.7 KEZ43378.1 - 0.05 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Beta-lactamase PF00144.24 KEZ43379.1 - 3.5e-31 108.7 0.1 6.2e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase Cyclase PF04199.13 KEZ43379.1 - 2.1e-16 60.4 0.0 3.9e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase SGL PF08450.12 KEZ43380.1 - 1.1e-14 54.7 0.8 1.5e-14 54.2 0.8 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KEZ43380.1 - 8.5e-05 22.4 0.3 0.088 12.9 0.0 4.1 3 0 0 3 3 3 2 NHL repeat Aldo_ket_red PF00248.21 KEZ43381.1 - 1.1e-22 80.7 0.0 1.2e-21 77.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Transketolase_N PF00456.21 KEZ43382.1 - 3.2e-125 417.5 0.1 7.1e-125 416.4 0.1 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KEZ43382.1 - 1.2e-37 129.3 0.0 3e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KEZ43382.1 - 4.6e-07 29.1 0.3 8.1e-07 28.3 0.3 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KEZ43382.1 - 6.5e-06 25.6 0.0 2.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 KEZ43382.1 - 1.6e-05 24.8 0.0 5.4e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 KEZ43382.1 - 0.00067 19.5 2.8 0.019 14.8 2.1 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 2OG-FeII_Oxy PF03171.20 KEZ43382.1 - 0.12 12.9 0.0 0.42 11.1 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily F_bP_aldolase PF01116.20 KEZ43383.1 - 1.1e-75 254.7 0.0 1.3e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CobS PF02654.15 KEZ43383.1 - 0.044 14.0 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase MFS_1 PF07690.16 KEZ43384.1 - 1.4e-17 63.7 32.8 1.4e-17 63.7 32.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEZ43384.1 - 6e-12 45.6 6.5 6e-12 45.6 6.5 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 KEZ43384.1 - 0.2 10.5 13.9 0.011 14.7 7.6 1.9 2 0 0 2 2 2 0 MFS_1 like family COX7a PF02238.15 KEZ43384.1 - 1.2 9.6 0.0 1.2 9.6 0.0 4.9 6 0 0 6 6 6 0 Cytochrome c oxidase subunit VII RasGEF PF00617.19 KEZ43385.1 - 3.9e-52 177.0 0.0 6.8e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEZ43385.1 - 1.7e-16 60.4 0.0 6.4e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 KEZ43385.1 - 3e-06 27.0 0.0 5.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ43385.1 - 0.00018 21.0 0.0 0.00037 20.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF4653 PF15546.6 KEZ43385.1 - 8.2 6.0 7.9 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) DUF1992 PF09350.10 KEZ43386.1 - 2e-19 69.5 0.6 7.1e-19 67.7 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) ANAPC10 PF03256.16 KEZ43388.1 - 0.15 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Pkinase PF00069.25 KEZ43389.1 - 2.9e-15 56.3 0.0 4.7e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43389.1 - 0.0011 18.3 0.0 0.0067 15.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ43389.1 - 0.12 11.7 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ADH_zinc_N_2 PF13602.6 KEZ43390.1 - 1.2e-16 61.9 0.0 2.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ43390.1 - 4.6e-09 36.3 0.0 1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ43390.1 - 0.00048 20.0 0.0 0.0064 16.4 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain YGGT PF02325.17 KEZ43390.1 - 0.024 15.1 0.2 5 7.6 0.0 2.4 2 0 0 2 2 2 0 YGGT family DapB_N PF01113.20 KEZ43390.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_N_2 PF16884.5 KEZ43390.1 - 0.054 13.4 0.0 0.23 11.4 0.0 2.1 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Tyrosinase PF00264.20 KEZ43391.1 - 1.2e-16 61.7 0.5 3.9e-16 60.0 0.3 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase ABC1 PF03109.16 KEZ43392.1 - 1.3e-21 77.0 0.0 5.3e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 KEZ43392.1 - 0.0018 17.9 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KEZ43392.1 - 0.031 14.2 0.1 0.076 12.9 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family CFEM PF05730.11 KEZ43393.1 - 1e-08 35.1 10.0 1.9e-08 34.3 10.0 1.5 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.11 KEZ43393.1 - 0.88 10.0 12.8 0.34 11.4 10.6 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MFS_1 PF07690.16 KEZ43394.1 - 6.5e-14 51.6 59.0 4.1e-11 42.4 57.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ43394.1 - 2.3e-12 46.1 19.6 3.4e-12 45.6 19.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Stevor PF17410.2 KEZ43394.1 - 4 6.9 5.6 0.87 9.1 0.6 2.3 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Pox_A14 PF05767.12 KEZ43394.1 - 6.4 7.0 8.8 0.17 12.0 0.8 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Acetyltransf_1 PF00583.25 KEZ43395.1 - 5.8e-06 26.5 0.0 9.4e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ43395.1 - 2.2e-05 24.8 0.0 4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ43395.1 - 4.4e-05 23.4 0.0 0.00022 21.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 KEZ43396.1 - 4.4e-41 141.0 0.3 6.8e-41 140.4 0.2 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ43396.1 - 4.5e-14 52.8 0.4 1.9e-11 44.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ43396.1 - 2.7e-08 33.8 1.9 0.091 12.3 0.0 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ43396.1 - 4e-07 29.6 0.3 9.6e-07 28.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ43396.1 - 1.7e-05 24.8 1.4 0.085 12.8 0.0 4.7 5 0 0 5 5 5 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KEZ43396.1 - 2.4e-05 23.6 0.4 0.001 18.3 0.1 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KEZ43396.1 - 4.3e-05 22.5 0.2 0.54 9.0 0.0 3.1 2 1 1 3 3 3 3 Tryptophan halogenase Lycopene_cycl PF05834.12 KEZ43396.1 - 0.00029 20.0 0.2 0.22 10.6 0.0 2.7 2 1 1 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 KEZ43396.1 - 0.00099 17.9 1.2 0.099 11.3 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 KEZ43396.1 - 0.0017 18.5 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KEZ43396.1 - 0.0023 17.3 1.7 0.9 8.8 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KEZ43396.1 - 0.0038 16.4 0.7 3.2 6.7 0.0 3.0 3 1 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 KEZ43396.1 - 0.011 15.0 0.6 0.19 10.9 0.0 2.4 2 1 0 2 2 2 0 Thi4 family Peptidase_S28 PF05577.12 KEZ43396.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 GIDA PF01134.22 KEZ43396.1 - 0.58 9.2 14.5 2.6 7.0 1.2 3.7 3 1 1 4 4 4 0 Glucose inhibited division protein A adh_short PF00106.25 KEZ43397.1 - 7.4e-39 133.2 2.3 9.4e-39 132.9 2.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43397.1 - 2.7e-31 108.9 4.5 3.4e-31 108.6 4.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43397.1 - 5e-12 46.1 1.6 6.7e-12 45.7 1.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ43397.1 - 0.029 13.8 0.2 0.074 12.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Alk_phosphatase PF00245.20 KEZ43397.1 - 0.087 11.8 1.0 0.12 11.4 1.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase GDP_Man_Dehyd PF16363.5 KEZ43397.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase K_channel_TID PF07941.11 KEZ43397.1 - 1.3 9.5 10.6 0.32 11.5 7.1 1.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain tRNA-synt_1 PF00133.22 KEZ43398.1 - 2.2e-205 683.5 0.0 2.9e-205 683.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEZ43398.1 - 2.3e-24 86.1 0.0 7.1e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KEZ43398.1 - 8.4e-16 57.7 1.2 1.1e-06 27.7 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KEZ43398.1 - 0.025 13.9 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF4768 PF15989.5 KEZ43398.1 - 0.16 11.9 0.8 0.38 10.7 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) Glyco_hydro_11 PF00457.17 KEZ43399.1 - 7.8e-82 273.2 19.5 1.1e-81 272.8 19.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KEZ43399.1 - 1.5e-11 44.1 19.0 1.5e-11 44.1 19.0 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KEZ43399.1 - 0.0085 16.3 8.4 0.02 15.2 8.4 1.7 1 1 0 1 1 1 1 Toxin 7 SET PF00856.28 KEZ43400.1 - 1.6e-07 31.9 0.0 3.3e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 SET domain UFD1 PF03152.14 KEZ43401.1 - 6.9e-30 103.8 0.0 1.5e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KEZ43401.1 - 5.5e-08 32.9 1.2 3.8e-06 27.0 0.0 2.9 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PknG_rubred PF16919.5 KEZ43401.1 - 0.0024 18.0 2.0 0.014 15.6 0.3 2.7 2 0 0 2 2 2 1 Protein kinase G rubredoxin domain zf-C2H2 PF00096.26 KEZ43401.1 - 0.01 16.2 17.2 0.53 10.8 0.1 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type RNF220 PF15926.5 KEZ43401.1 - 0.29 10.7 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 zf-ribbon_3 PF13248.6 KEZ43401.1 - 0.39 10.2 12.2 0.5 9.9 0.5 4.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 KEZ43401.1 - 3.4 7.8 6.5 3.5 7.7 0.5 3.4 2 1 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.7 KEZ43402.1 - 0.28 11.1 0.1 0.28 11.1 0.1 2.5 3 0 0 3 3 3 0 F-box-like Actin PF00022.19 KEZ43403.1 - 7.2e-99 331.1 0.0 6.8e-98 327.9 0.0 1.9 1 1 0 1 1 1 1 Actin CDH-cyt PF16010.5 KEZ43404.1 - 3.9e-51 173.3 0.0 7.5e-51 172.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase SGL PF08450.12 KEZ43404.1 - 0.0016 18.1 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DOMON PF03351.17 KEZ43404.1 - 0.021 15.0 0.1 0.048 13.9 0.1 1.6 1 0 0 1 1 1 0 DOMON domain zf-C3HC4_3 PF13920.6 KEZ43405.1 - 0.048 13.5 7.7 0.058 13.3 3.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KEZ43405.1 - 0.077 13.1 3.1 0.16 12.1 3.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.11 KEZ43405.1 - 0.083 12.8 0.3 0.13 12.2 0.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 KEZ43405.1 - 0.37 10.8 6.3 0.82 9.7 6.3 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KEZ43405.1 - 0.71 10.3 8.1 0.23 11.8 4.2 1.9 2 0 0 2 2 2 0 Ring finger domain Peptidase_S49_N PF08496.10 KEZ43405.1 - 7 6.7 11.5 8.6 6.4 6.7 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-RING_UBOX PF13445.6 KEZ43405.1 - 8.7 6.5 7.3 21 5.3 7.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Sugar_tr PF00083.24 KEZ43406.1 - 4.5e-75 253.2 12.2 2.7e-72 244.1 11.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43406.1 - 9.1e-31 107.1 26.1 1.4e-30 106.5 26.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KEZ43407.1 - 9.2e-19 67.6 45.5 2.3e-17 63.0 13.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43407.1 - 2.1e-11 43.3 0.7 2.1e-11 43.3 0.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ43407.1 - 0.00069 18.6 4.0 0.0086 15.0 0.1 2.3 2 0 0 2 2 2 2 MFS_1 like family IMUP PF15761.5 KEZ43407.1 - 0.084 13.6 0.5 0.084 13.6 0.5 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Bac_surface_Ag PF01103.23 KEZ43408.1 - 5.5e-37 128.0 0.0 6.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 KEZ43408.1 - 0.014 14.9 0.1 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB UQ_con PF00179.26 KEZ43409.1 - 7.9e-21 74.2 0.1 1.7e-20 73.1 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme MFS_1 PF07690.16 KEZ43410.1 - 2.3e-26 92.6 34.8 2.3e-26 92.6 34.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43410.1 - 1.2e-13 50.7 11.9 1.2e-13 50.7 11.9 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 KEZ43413.1 - 1e-17 64.5 0.1 2.1e-17 63.5 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ43413.1 - 3.1e-17 62.4 3.9 3.8e-08 33.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43413.1 - 3.1e-17 60.9 0.7 0.00012 22.2 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KEZ43413.1 - 1e-16 60.5 2.1 9.8e-06 25.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KEZ43413.1 - 9e-15 54.8 0.1 1.9e-09 37.8 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF3328 PF11807.8 KEZ43414.1 - 1.1e-08 35.2 0.4 1.5e-08 34.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KEZ43415.1 - 2.9e-21 76.3 0.1 3.6e-21 76.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) IPU_b_solenoid PF18783.1 KEZ43416.1 - 1.4e-05 25.0 6.3 0.22 11.6 0.1 4.3 4 0 0 4 4 4 3 Isopullulanase beta-solenoid repeat Autotransporter PF03797.19 KEZ43416.1 - 0.01 15.5 0.9 0.032 13.9 0.9 1.8 1 1 0 1 1 1 0 Autotransporter beta-domain IPI_T4 PF11634.8 KEZ43416.1 - 0.022 14.7 6.3 1.4 9.0 0.1 3.5 1 1 3 4 4 4 0 Nuclease inhibitor from bacteriophage T4 NT5C PF06941.12 KEZ43416.1 - 0.082 12.8 0.1 20 5.0 0.0 2.7 1 1 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF1459 PF07312.11 KEZ43416.1 - 0.83 9.9 2.5 56 4.0 0.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1459) DUF3328 PF11807.8 KEZ43417.1 - 2.7e-47 161.4 0.4 3.8e-47 160.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KEZ43418.1 - 3.7e-57 193.6 2.4 4.8e-57 193.3 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.6 KEZ43419.1 - 2.6e-21 76.2 0.0 3.9e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ43419.1 - 1.2e-08 35.6 0.0 5.2e-08 33.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43419.1 - 2.9e-08 33.7 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ43419.1 - 5.6e-06 27.0 0.0 0.00016 22.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ43419.1 - 2.8e-05 24.7 0.0 6.7e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ43419.1 - 0.00074 19.1 0.0 0.0047 16.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KEZ43419.1 - 0.0014 18.4 0.0 0.0037 17.0 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase FtsJ PF01728.19 KEZ43419.1 - 0.013 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KEZ43419.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KEZ43419.1 - 0.076 12.5 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DUF1996 PF09362.10 KEZ43420.1 - 7.5e-69 232.3 0.7 9.3e-69 232.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Tyrosinase PF00264.20 KEZ43421.1 - 8.1e-45 153.8 0.1 1.1e-44 153.4 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 KEZ43421.1 - 0.22 12.2 0.0 0.37 11.4 0.0 1.3 1 0 0 1 1 1 0 HMG-box domain DUF2231 PF09990.9 KEZ43422.1 - 0.71 10.3 7.0 1 9.8 6.0 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) Goodbye PF17109.5 KEZ43423.1 - 8.2e-27 94.1 0.7 2.1e-26 92.7 0.0 2.1 2 0 0 2 2 1 1 fungal STAND N-terminal Goodbye domain TPR_1 PF00515.28 KEZ43423.1 - 2.4e-14 52.4 2.2 0.00039 20.1 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ43423.1 - 1.2e-11 43.8 6.0 0.0034 17.4 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ43423.1 - 1e-10 40.9 6.0 0.0054 16.8 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ43423.1 - 2.4e-09 37.3 7.8 0.12 12.7 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ43423.1 - 5.6e-09 36.4 7.1 0.034 14.6 0.1 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat AAA_22 PF13401.6 KEZ43423.1 - 1.3e-07 31.9 0.5 4e-06 27.1 0.0 3.2 2 1 1 3 3 3 1 AAA domain TPR_16 PF13432.6 KEZ43423.1 - 5.6e-07 30.1 2.7 2.8 8.7 0.0 5.7 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ43423.1 - 1.9e-06 28.2 3.1 0.47 11.4 0.0 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ43423.1 - 6.3e-06 25.9 3.2 0.53 10.4 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ43423.1 - 6.3e-06 26.7 0.0 3.1e-05 24.4 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEZ43423.1 - 2.8e-05 24.1 0.0 0.0001 22.2 0.0 2.0 1 0 0 1 1 1 1 NACHT domain ANAPC3 PF12895.7 KEZ43423.1 - 3.7e-05 23.9 0.5 0.5 10.6 0.1 4.5 5 0 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KEZ43423.1 - 4.2e-05 23.3 2.1 12 6.0 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 KEZ43423.1 - 0.0016 18.6 0.2 13 6.3 0.0 4.9 5 0 0 5 5 3 0 PPR repeat TPR_6 PF13174.6 KEZ43423.1 - 0.0062 17.1 13.8 0.87 10.4 0.0 6.6 7 0 0 7 7 5 1 Tetratricopeptide repeat RNA_helicase PF00910.22 KEZ43423.1 - 0.01 16.2 0.0 0.05 14.0 0.0 2.2 2 0 0 2 2 1 0 RNA helicase RPN7 PF10602.9 KEZ43423.1 - 0.014 15.1 0.5 8.5 6.0 0.0 4.4 3 2 1 4 4 4 0 26S proteasome subunit RPN7 AAA_5 PF07728.14 KEZ43423.1 - 0.015 15.3 0.0 8.4 6.4 0.0 3.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) TPR_11 PF13414.6 KEZ43423.1 - 0.018 14.7 0.3 5.3 6.8 0.1 3.6 3 0 0 3 3 3 0 TPR repeat AAA_18 PF13238.6 KEZ43423.1 - 0.018 15.6 0.1 1.3 9.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 KEZ43423.1 - 0.091 12.1 0.0 0.69 9.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KEZ43423.1 - 0.11 12.9 0.0 2.1 8.8 0.0 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) zf-UBP_var PF17807.1 KEZ43423.1 - 0.25 11.1 1.1 0.52 10.1 1.1 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger HET PF06985.11 KEZ43427.1 - 2.7e-11 44.0 1.3 2.7e-11 44.0 1.3 3.7 2 2 1 3 3 3 2 Heterokaryon incompatibility protein (HET) LMBR1 PF04791.16 KEZ43427.1 - 9.4 5.0 7.3 13 4.5 7.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CoA_trans PF01144.23 KEZ43428.1 - 9.4e-95 316.1 0.4 4.6e-58 196.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KEZ43428.1 - 0.011 15.7 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KEZ43428.1 - 0.026 12.9 0.0 0.1 10.9 0.0 1.8 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter DUF3455 PF11937.8 KEZ43429.1 - 1.3e-36 126.4 0.0 1.6e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Glyco_hydro_15 PF00723.21 KEZ43430.1 - 1.8e-93 313.8 0.1 4.1e-93 312.6 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KEZ43430.1 - 1.4e-30 105.0 1.6 2.6e-30 104.2 0.1 2.2 2 0 0 2 2 2 1 Starch binding domain 3HCDH_RFF PF18321.1 KEZ43430.1 - 0.16 12.5 0.8 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain ERG4_ERG24 PF01222.17 KEZ43431.1 - 1.3e-149 498.7 16.4 1.6e-149 498.4 16.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Glyco_hydro_18 PF00704.28 KEZ43433.1 - 6.2e-24 85.3 3.5 1.1e-23 84.4 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 KEZ43433.1 - 0.1 12.8 0.8 0.27 11.5 0.8 1.6 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain AAA PF00004.29 KEZ43434.1 - 1.5e-16 61.0 0.0 2.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ43434.1 - 0.00011 22.5 0.5 0.0034 17.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ43434.1 - 0.00025 21.2 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ43434.1 - 0.0023 18.5 0.0 0.0047 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEZ43434.1 - 0.0098 15.6 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 KEZ43434.1 - 0.014 15.4 0.0 0.093 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KEZ43434.1 - 0.02 15.3 0.3 0.082 13.3 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 KEZ43434.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zot PF05707.12 KEZ43434.1 - 0.069 12.8 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) p450 PF00067.22 KEZ43435.1 - 2.4e-26 92.5 0.0 2.9e-20 72.4 0.1 3.1 1 1 1 2 2 2 2 Cytochrome P450 Beta-lactamase PF00144.24 KEZ43436.1 - 4.3e-24 85.4 0.3 8.6e-24 84.4 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase UDPGT PF00201.18 KEZ43437.1 - 1.8e-12 46.8 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_4 PF13692.6 KEZ43437.1 - 0.058 13.8 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 ABC2_membrane PF01061.24 KEZ43438.1 - 1.3e-74 250.2 62.6 2.5e-42 144.7 24.6 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ43438.1 - 2.6e-36 125.2 0.0 2.3e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEZ43438.1 - 1.1e-35 121.4 1.3 1.7e-31 108.0 0.0 3.7 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KEZ43438.1 - 2.1e-15 57.1 0.0 5.1e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KEZ43438.1 - 1.6e-07 31.1 0.0 5e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ43438.1 - 2.6e-06 27.7 0.1 0.073 13.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KEZ43438.1 - 3.6e-06 27.5 0.3 0.0039 17.6 0.1 2.8 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ43438.1 - 3.5e-05 23.8 0.1 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KEZ43438.1 - 0.00033 20.3 0.5 0.044 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 KEZ43438.1 - 0.00055 19.2 41.8 0.0082 15.3 19.8 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KEZ43438.1 - 0.00066 20.2 0.0 0.056 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KEZ43438.1 - 0.0012 18.4 0.0 0.097 12.1 0.0 3.3 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KEZ43438.1 - 0.0019 18.6 0.1 2 8.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEZ43438.1 - 0.0055 16.6 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 KEZ43438.1 - 0.01 15.5 0.2 0.22 11.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEZ43438.1 - 0.012 15.6 0.2 2.6 7.9 0.2 2.9 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KEZ43438.1 - 0.038 14.3 0.3 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 KEZ43438.1 - 0.05 13.5 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 KEZ43438.1 - 0.059 13.1 0.4 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KEZ43438.1 - 0.1 13.0 0.1 28 5.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KEZ43438.1 - 0.24 11.6 1.8 3.4 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain GMC_oxred_N PF00732.19 KEZ43439.1 - 1.2e-65 221.8 0.0 1.9e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ43439.1 - 2.5e-33 115.6 0.0 4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ43439.1 - 1.2e-06 27.9 0.1 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ43439.1 - 0.00023 20.8 0.2 0.04 13.5 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ43439.1 - 0.0042 17.3 0.1 0.012 15.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ43439.1 - 0.0062 15.8 0.8 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ43439.1 - 0.0084 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ43439.1 - 0.013 14.7 0.4 0.044 13.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KEZ43439.1 - 0.014 14.2 0.2 0.072 11.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KEZ43439.1 - 0.019 15.5 0.5 2.7 8.6 0.0 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEZ43439.1 - 0.021 15.1 1.8 0.86 9.9 0.1 2.7 2 1 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KEZ43439.1 - 0.16 11.2 0.0 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase eIF_4G1 PF12152.8 KEZ43441.1 - 0.17 12.1 0.0 0.53 10.5 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 MFS_1 PF07690.16 KEZ43442.1 - 1.6e-40 139.1 32.5 1.6e-40 139.1 32.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43442.1 - 3.5e-10 39.3 8.7 3.5e-10 39.3 8.7 3.6 2 2 0 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ43442.1 - 1.6e-07 30.2 2.7 2.4e-07 29.6 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cu-oxidase_2 PF07731.14 KEZ43443.1 - 5.5e-27 94.2 2.3 2e-23 82.6 2.9 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEZ43443.1 - 5.9e-20 71.5 0.0 1.5e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Myb_DNA-bind_6 PF13921.6 KEZ43445.1 - 0.0074 16.5 3.0 0.0074 16.5 3.0 2.3 2 1 1 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KEZ43445.1 - 0.044 14.0 3.0 0.31 11.3 0.9 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA_12 PF13087.6 KEZ43447.1 - 2.8e-21 76.1 0.0 4.9e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ43447.1 - 4.2e-09 36.6 0.0 2.5e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ43447.1 - 0.00019 21.2 0.0 1.1 8.9 0.0 2.9 4 0 0 4 4 4 2 AAA domain UvrD_C_2 PF13538.6 KEZ43447.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain F-box-like PF12937.7 KEZ43448.1 - 2.3e-05 24.2 0.1 6.6e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ43448.1 - 0.019 14.8 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 F-box domain FBA PF04300.13 KEZ43448.1 - 0.092 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 F-box associated region DUF1996 PF09362.10 KEZ43449.1 - 1.6e-73 247.5 0.5 2.1e-73 247.2 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.11 KEZ43450.1 - 2.2e-26 93.0 0.0 3.5e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4335 PF14233.6 KEZ43451.1 - 0.22 11.4 0.0 0.29 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) FMN_red PF03358.15 KEZ43452.1 - 3.3e-24 85.4 0.0 6.2e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase F-box PF00646.33 KEZ43452.1 - 0.00091 19.1 0.0 0.0028 17.5 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KEZ43452.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Rhodanese PF00581.20 KEZ43452.1 - 0.011 16.3 0.0 0.096 13.2 0.0 2.4 2 0 0 2 2 2 0 Rhodanese-like domain 2-Hacid_dh_C PF02826.19 KEZ43452.1 - 0.16 11.4 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SBF PF01758.16 KEZ43453.1 - 3.7e-51 173.6 9.4 3.7e-51 173.6 9.4 2.2 3 1 0 3 3 3 1 Sodium Bile acid symporter family Mid2 PF04478.12 KEZ43453.1 - 5.9 6.7 4.9 29 4.5 0.6 2.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor bZIP_1 PF00170.21 KEZ43454.1 - 0.2 11.8 9.1 0.28 11.3 7.9 1.8 1 1 0 1 1 1 0 bZIP transcription factor Sugar_tr PF00083.24 KEZ43455.1 - 4.1e-19 68.8 10.4 1.8e-10 40.3 3.8 3.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43455.1 - 1.1e-09 37.7 9.5 0.0017 17.4 4.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily RTA1 PF04479.13 KEZ43456.1 - 2.1e-69 233.3 10.1 2.1e-69 233.3 10.1 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF202 PF02656.15 KEZ43456.1 - 0.38 11.2 0.1 0.38 11.2 0.1 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF202) Ndc1_Nup PF09531.10 KEZ43456.1 - 0.39 9.3 5.4 0.49 9.0 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3413 PF11893.8 KEZ43456.1 - 0.84 8.7 8.5 0.58 9.3 2.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3413) Na_H_Exchanger PF00999.21 KEZ43457.1 - 3.7e-41 141.2 16.9 5.1e-41 140.7 16.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KEZ43457.1 - 0.00063 19.8 2.6 0.001 19.1 0.1 2.6 2 0 0 2 2 2 1 YrhC-like protein TauD PF02668.16 KEZ43458.1 - 3e-34 119.1 0.0 5.7e-34 118.1 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEZ43458.1 - 0.0052 15.9 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 CsiD DUF3933 PF13069.6 KEZ43459.1 - 0.18 11.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Ras PF00071.22 KEZ43460.1 - 7.2e-24 84.2 0.0 1.5e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ43460.1 - 8.8e-12 45.3 0.0 2.4e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Helo_like_N PF17111.5 KEZ43460.1 - 1.4e-10 40.9 0.2 2.7e-10 40.0 0.2 1.4 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins MMR_HSR1 PF01926.23 KEZ43460.1 - 0.0084 16.2 0.0 0.028 14.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 KEZ43460.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 KEZ43460.1 - 0.046 14.1 0.3 0.32 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain SesA PF17107.5 KEZ43460.1 - 0.086 13.0 0.4 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ACT PF01842.25 KEZ43460.1 - 0.16 11.8 0.1 0.71 9.7 0.2 2.1 2 0 0 2 2 2 0 ACT domain PduV-EutP PF10662.9 KEZ43460.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gemini_mov PF01708.16 KEZ43461.1 - 0.15 11.8 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein TRI12 PF06609.13 KEZ43463.1 - 1.6e-25 89.7 22.4 2e-25 89.3 22.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KEZ43463.1 - 8.1e-25 87.5 54.7 4.5e-23 81.7 52.7 3.4 2 1 0 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 KEZ43464.1 - 1.8e-38 132.0 0.0 2.5e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43464.1 - 2.6e-31 109.0 0.0 3.4e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43464.1 - 0.00063 19.7 0.0 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 KR domain AlaDh_PNT_C PF01262.21 KEZ43464.1 - 0.024 13.9 0.2 0.041 13.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KEZ43465.1 - 1.7e-30 106.1 39.3 1.7e-30 106.1 39.3 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_tranf_2_3 PF13641.6 KEZ43466.1 - 9.4e-14 51.8 0.2 1.4e-13 51.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KEZ43466.1 - 2.3e-10 40.5 0.0 4.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ43466.1 - 5.8e-05 22.6 0.2 0.093 12.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 DoxX PF07681.12 KEZ43466.1 - 0.052 14.1 0.1 0.12 13.0 0.1 1.6 1 1 0 1 1 1 0 DoxX DUF2938 PF11158.8 KEZ43467.1 - 0.16 11.5 1.5 0.28 10.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2938) Transferase PF02458.15 KEZ43468.1 - 3.2e-14 52.4 0.0 1.2e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 Transferase family Peptidase_S15 PF02129.18 KEZ43469.1 - 0.01 15.5 0.3 0.032 13.8 0.2 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Transferase PF02458.15 KEZ43470.1 - 4.5e-28 98.1 0.0 7.5e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 KEZ43470.1 - 0.00026 19.8 0.0 0.00043 19.1 0.0 1.2 1 0 0 1 1 1 1 Condensation domain FMO-like PF00743.19 KEZ43472.1 - 8e-22 77.4 0.7 7.2e-20 70.9 0.2 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ43472.1 - 1.3e-11 44.6 0.0 3.6e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ43472.1 - 4.4e-05 22.9 0.0 0.0076 15.5 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ43472.1 - 0.00017 20.9 0.0 0.031 13.4 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KEZ43472.1 - 0.00018 21.3 0.0 0.64 9.5 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ43472.1 - 0.014 15.4 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Abhydrolase_3 PF07859.13 KEZ43473.1 - 1.6e-26 93.4 0.0 7.5e-26 91.3 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KEZ43473.1 - 9.2e-05 22.1 0.0 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KEZ43473.1 - 0.00083 18.9 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KEZ43473.1 - 0.31 9.9 0.1 0.6 8.9 0.1 1.4 1 0 0 1 1 1 0 Steryl acetyl hydrolase bZIP_1 PF00170.21 KEZ43474.1 - 0.12 12.5 13.5 0.54 10.4 13.5 2.0 1 1 0 1 1 1 0 bZIP transcription factor DUF802 PF05650.11 KEZ43474.1 - 0.21 12.1 3.5 0.71 10.4 3.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF802) BCL9 PF11502.8 KEZ43474.1 - 0.63 9.9 5.0 1.5 8.7 5.0 1.6 1 0 0 1 1 1 0 B-cell lymphoma 9 protein p450 PF00067.22 KEZ43475.1 - 2.9e-29 102.1 0.0 3.8e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 KEZ43475.1 - 7.8e-16 58.2 0.0 3.1e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.25 KEZ43476.1 - 8.8e-23 80.8 1.2 9.2e-21 74.2 0.5 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43476.1 - 4.2e-14 52.7 1.0 7.4e-13 48.6 0.3 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43476.1 - 6.9e-09 35.9 0.5 1.1e-08 35.2 0.5 1.3 1 0 0 1 1 1 1 KR domain Pectate_lyase_3 PF12708.7 KEZ43479.1 - 2.4e-75 253.1 0.6 1.9e-66 224.0 0.1 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KEZ43479.1 - 0.00055 19.6 0.9 0.26 11.0 0.1 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 KEZ43479.1 - 0.053 13.9 0.3 3.5 8.0 0.0 2.8 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB Annexin PF00191.20 KEZ43480.1 - 2.1e-47 159.0 2.9 1.3e-13 50.8 0.1 4.2 4 0 0 4 4 4 4 Annexin ADH_zinc_N PF00107.26 KEZ43481.1 - 7.7e-30 103.5 0.7 1.4e-29 102.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ43481.1 - 5.7e-21 76.0 0.0 1.1e-20 75.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ43481.1 - 2.3e-10 40.3 0.0 5.1e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KEZ43481.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain AA_permease_2 PF13520.6 KEZ43483.1 - 9.4e-39 133.4 26.9 1.1e-33 116.7 14.5 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KEZ43483.1 - 1.5e-10 40.3 24.7 2.4e-10 39.6 15.4 3.0 2 1 0 2 2 2 2 Amino acid permease MFS_1_like PF12832.7 KEZ43483.1 - 0.018 13.9 1.7 0.034 13.0 1.7 1.7 1 1 0 1 1 1 0 MFS_1 like family BatA PF07584.11 KEZ43483.1 - 0.12 12.8 0.3 0.12 12.8 0.3 3.2 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal F-box PF00646.33 KEZ43484.1 - 2.4e-09 36.8 0.3 2.4e-09 36.8 0.3 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KEZ43484.1 - 1.1e-06 28.5 0.9 3.1e-06 27.0 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KEZ43484.1 - 0.016 15.1 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 F-box F-box-like_2 PF13013.6 KEZ43484.1 - 0.072 13.1 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like domain GMC_oxred_N PF00732.19 KEZ43485.1 - 2.7e-60 204.3 0.0 3.4e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ43485.1 - 1.6e-30 106.5 0.0 2.5e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KEZ43485.1 - 1.5e-05 24.3 0.2 3.3e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KEZ43485.1 - 0.00011 22.4 0.0 0.0005 20.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ43485.1 - 0.00013 21.1 0.0 0.00026 20.2 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEZ43485.1 - 0.0076 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 KEZ43485.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ43485.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KEZ43485.1 - 0.023 15.0 0.1 0.073 13.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 KEZ43485.1 - 0.071 12.3 0.1 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 KEZ43485.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) G-alpha PF00503.20 KEZ43486.1 - 1.1e-08 34.7 0.0 1.3e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 G-protein alpha subunit Ank_2 PF12796.7 KEZ43487.1 - 1.1e-49 167.0 0.0 3.4e-15 56.4 0.0 5.0 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43487.1 - 1.2e-26 92.7 0.2 7.7e-09 35.9 0.0 7.0 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ43487.1 - 1.5e-24 85.8 2.7 2.2e-05 24.7 0.0 6.4 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43487.1 - 5.7e-23 78.5 0.8 0.0043 17.4 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KEZ43487.1 - 1.4e-22 79.0 0.1 6e-05 23.3 0.0 7.1 7 1 0 7 7 7 4 Ankyrin repeat Zn_clus PF00172.18 KEZ43487.1 - 0.34 11.1 9.4 0.84 9.8 9.4 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KEZ43488.1 - 4.1e-48 163.4 0.0 1e-26 94.0 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KEZ43489.1 - 4.7e-25 88.2 20.3 8.3e-25 87.4 20.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43489.1 - 3.5e-08 32.8 9.1 4.2e-07 29.2 0.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KEZ43489.1 - 4.7e-05 22.0 3.7 4.7e-05 22.0 3.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 KEZ43489.1 - 0.00045 20.0 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KEZ43489.1 - 0.0055 16.6 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 1 F-box TM_helix PF05552.12 KEZ43489.1 - 0.31 11.1 3.3 7.6 6.6 0.0 3.0 2 0 0 2 2 2 0 Conserved TM helix DUF2235 PF09994.9 KEZ43490.1 - 7e-87 291.4 0.0 1.3e-86 290.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PI_PP_C PF18365.1 KEZ43491.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Ribosomal_S2 PF00318.20 KEZ43492.1 - 1.4e-64 217.3 0.1 3.6e-63 212.7 0.0 2.8 2 1 0 2 2 2 1 Ribosomal protein S2 Anthrax-tox_M PF09156.10 KEZ43492.1 - 0.93 8.8 3.7 1.4 8.2 3.7 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain CBS PF00571.28 KEZ43493.1 - 5.9e-36 122.7 6.6 2e-09 37.8 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KEZ43493.1 - 2.8e-08 33.6 0.0 9.2e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 PB1 domain zf-C2H2 PF00096.26 KEZ43494.1 - 2e-09 37.4 17.3 0.00018 21.8 5.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ43494.1 - 6.9e-07 29.4 11.1 0.0033 17.8 2.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ43494.1 - 3.1e-05 24.5 15.6 0.092 13.6 4.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KEZ43494.1 - 0.0024 17.6 6.7 0.026 14.3 1.3 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-UBR PF02207.20 KEZ43494.1 - 0.72 10.1 5.7 1.4 9.1 5.7 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) C1_4 PF07975.12 KEZ43494.1 - 1.3 9.3 6.4 2.9 8.2 6.4 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 KEZ43494.1 - 2.8 8.0 10.4 8.9 6.4 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4470 PF14737.6 KEZ43495.1 - 1.5e-07 31.5 0.0 1e-06 28.8 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KEZ43495.1 - 0.37 10.9 6.4 0.68 10.1 6.4 1.4 1 0 0 1 1 1 0 MYND finger Cpn60_TCP1 PF00118.24 KEZ43496.1 - 6.5e-163 542.9 0.6 7.8e-163 542.6 0.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.13 KEZ43496.1 - 1.5e-44 152.2 0.2 2.9e-43 148.0 0.0 2.7 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Herpes_UL6 PF01763.16 KEZ43496.1 - 0.056 12.0 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like CSN8_PSD8_EIF3K PF10075.9 KEZ43497.1 - 1.5e-38 132.0 0.0 2e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DNA_ligase_A_M PF01068.21 KEZ43498.1 - 1.2e-50 172.0 0.1 6.2e-48 163.1 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEZ43498.1 - 5.7e-24 85.4 0.0 1.3e-23 84.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KEZ43498.1 - 1.3e-18 67.4 0.0 7.1e-18 65.0 0.0 2.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KEZ43498.1 - 2.6e-05 24.6 0.0 5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase Adaptin_N PF01602.20 KEZ43499.1 - 1.5e-138 462.6 2.9 2.1e-138 462.2 2.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KEZ43499.1 - 4.5e-62 208.9 1.7 7.1e-60 201.7 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ43499.1 - 2.9e-17 62.8 0.1 5.3e-07 29.9 0.0 5.4 2 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 KEZ43499.1 - 7.8e-12 44.4 4.9 0.0042 17.2 0.0 6.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 KEZ43499.1 - 1.1e-05 25.8 0.2 0.63 10.6 0.0 5.1 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 KEZ43499.1 - 8.1e-05 22.6 0.6 0.0014 18.6 0.0 2.8 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central RIX1 PF08167.12 KEZ43499.1 - 0.0026 17.5 0.1 0.76 9.5 0.0 2.7 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis Arm PF00514.23 KEZ43499.1 - 0.0062 16.5 0.9 5.5 7.2 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KEZ43499.1 - 0.015 14.9 0.0 2.1 7.8 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 KEZ43499.1 - 0.027 14.6 0.7 2.4 8.3 0.0 3.9 1 1 2 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 BolA PF01722.18 KEZ43500.1 - 2.6e-18 66.0 0.0 5.2e-18 65.1 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 KEZ43501.1 - 4.5e-58 196.8 0.0 5.7e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Sugarporin_N PF11471.8 KEZ43501.1 - 0.086 12.8 0.6 0.21 11.6 0.6 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Vps51 PF08700.11 KEZ43502.1 - 2.3e-25 88.5 0.0 4.2e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KEZ43502.1 - 0.00012 20.9 0.1 0.00016 20.5 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family SLBP_RNA_bind PF15247.6 KEZ43502.1 - 0.091 12.9 0.6 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain TPR_2 PF07719.17 KEZ43503.1 - 1.2e-29 100.0 41.9 0.0091 16.0 0.0 17.6 20 0 0 20 20 18 9 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ43503.1 - 4.5e-28 95.9 18.4 0.0025 17.5 0.0 15.2 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ43503.1 - 4.3e-26 91.3 41.6 1.4e-05 25.6 0.5 12.0 12 2 3 15 15 13 7 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ43503.1 - 2.1e-24 85.8 22.7 0.042 14.4 0.0 11.5 11 1 1 12 12 12 7 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ43503.1 - 2.1e-23 81.0 28.9 0.02 15.7 0.5 15.1 12 3 3 15 15 13 4 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ43503.1 - 3.4e-21 74.0 19.7 0.32 11.5 0.0 15.1 19 0 0 19 19 16 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ43503.1 - 1.2e-16 60.1 9.3 0.0041 16.8 0.0 10.5 10 1 1 11 11 11 4 TPR repeat TPR_8 PF13181.6 KEZ43503.1 - 6.6e-15 54.0 38.7 0.03 14.5 0.2 16.0 19 0 0 19 19 18 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ43503.1 - 5.9e-14 52.1 39.7 0.0029 17.9 0.0 12.9 11 4 2 14 14 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ43503.1 - 1.4e-11 43.6 23.2 0.023 14.7 0.0 11.6 15 0 0 15 15 12 4 Tetratricopeptide repeat TPR_22 PF18833.1 KEZ43503.1 - 7.2e-08 32.5 0.0 2.7e-07 30.6 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ43503.1 - 2.5e-05 24.4 10.1 0.029 14.5 0.7 6.9 7 2 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ43503.1 - 0.00014 22.3 43.5 1.5 9.6 0.0 15.1 20 0 0 20 20 14 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KEZ43503.1 - 0.02 15.0 2.8 7 6.8 0.0 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 ComR_TPR PF18710.1 KEZ43503.1 - 0.034 13.7 0.1 7 6.1 0.1 2.7 2 0 0 2 2 2 0 ComR tetratricopeptide ChAPs PF09295.10 KEZ43503.1 - 0.037 13.0 0.4 12 4.7 0.0 3.7 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 KEZ43503.1 - 0.059 14.0 35.3 0.39 11.5 0.1 10.7 12 0 0 12 12 9 0 Tetratricopeptide repeat DUF627 PF04781.12 KEZ43503.1 - 0.1 12.6 0.2 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF627) TPR_20 PF14561.6 KEZ43503.1 - 0.15 12.4 16.5 9.7 6.6 1.3 6.6 7 1 0 7 7 5 0 Tetratricopeptide repeat FAT PF02259.23 KEZ43503.1 - 0.49 9.6 9.4 13 4.9 0.7 4.7 4 1 0 5 5 5 0 FAT domain DUF4192 PF13830.6 KEZ43503.1 - 0.74 9.8 14.8 0.22 11.5 0.1 4.0 5 0 0 5 5 4 0 Domain of unknown function (DUF4192) ANAPC3 PF12895.7 KEZ43503.1 - 1.2 9.4 20.4 3 8.1 0.0 8.2 9 2 0 10 10 9 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_5_C PF18564.1 KEZ43504.1 - 9.5e-22 77.4 0.0 2.5e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KEZ43504.1 - 1.1e-10 41.4 0.8 6.1e-07 29.2 0.2 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KEZ43504.1 - 0.016 14.6 0.0 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase Pkinase PF00069.25 KEZ43505.1 - 1.6e-62 211.3 0.0 2.2e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43505.1 - 3.6e-48 164.1 0.0 5.9e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ43505.1 - 1.2e-06 28.1 0.0 5.9e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KEZ43505.1 - 0.009 14.8 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KEZ43505.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ43505.1 - 0.087 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2_jaz PF12171.8 KEZ43505.1 - 0.21 11.9 0.9 0.41 11.0 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SAM_3 PF18016.1 KEZ43505.1 - 0.22 11.4 0.2 0.58 10.0 0.2 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glyco_hydro_47 PF01532.20 KEZ43506.1 - 9e-180 598.4 0.0 1.1e-179 598.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 KEZ43506.1 - 0.16 11.5 2.1 1.8 8.0 0.1 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 Fig1 PF12351.8 KEZ43507.1 - 8e-57 192.2 4.6 8e-57 192.2 4.6 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KEZ43507.1 - 1.2e-06 28.3 11.4 1.2e-06 28.3 11.4 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 KEZ43507.1 - 0.0069 15.5 12.6 0.011 14.8 12.5 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 KEZ43507.1 - 4 6.1 16.1 0.16 10.7 0.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 KEZ43507.1 - 6.3 6.4 8.2 0.2 11.3 0.2 2.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF624 PF04854.14 KEZ43508.1 - 0.26 11.4 0.0 0.46 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Cyanate_lyase PF02560.14 KEZ43509.1 - 7.5e-33 112.2 0.0 1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KEZ43509.1 - 0.00017 21.8 0.1 0.00028 21.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 KEZ43509.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1744 PF08490.12 KEZ43510.1 - 1.5e-137 458.4 0.0 2.2e-137 457.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KEZ43510.1 - 4.2e-76 256.3 0.1 1.2e-75 254.7 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KEZ43510.1 - 4.6e-14 52.0 3.8 4.2e-12 45.5 0.0 3.9 3 2 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KEZ43510.1 - 4.3e-08 33.1 0.1 1.2e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KEZ43510.1 - 6.5e-05 23.0 0.2 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.8 KEZ43511.1 - 4.5e-31 106.7 0.1 7.5e-31 106.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.12 KEZ43511.1 - 0.047 13.2 1.5 0.064 12.8 1.5 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT RsbU_N PF08673.10 KEZ43511.1 - 0.061 13.4 0.1 5.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain Gly-zipper_YMGG PF13441.6 KEZ43511.1 - 2.8 7.7 10.1 4.8 7.0 10.1 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 KEZ43511.1 - 3.1 8.0 8.6 6 7.1 8.6 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Aldose_epim PF01263.20 KEZ43512.1 - 1.3e-52 179.0 0.0 3.7e-52 177.5 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase VID27 PF08553.10 KEZ43514.1 - 5.8e-192 637.4 0.0 7.6e-192 637.0 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KEZ43514.1 - 2e-74 249.2 0.6 2e-74 249.2 0.6 3.5 3 1 0 3 3 2 1 VID27 N-terminal region VID27_PH PF17747.1 KEZ43514.1 - 4.2e-44 149.3 1.8 7.7e-44 148.4 0.7 2.0 2 0 0 2 2 2 1 VID27 PH-like domain DUF1281 PF06924.11 KEZ43514.1 - 0.081 12.5 0.3 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) CPSF100_C PF13299.6 KEZ43514.1 - 0.18 11.9 5.9 0.36 11.0 5.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 KEZ43514.1 - 0.2 9.7 17.4 0.36 8.9 17.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KEZ43514.1 - 0.84 7.8 14.9 1.3 7.1 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KEZ43514.1 - 0.87 8.9 15.9 1.4 8.2 15.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 KEZ43514.1 - 0.92 7.7 11.1 1.4 7.2 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KEZ43514.1 - 1.2 8.4 14.2 2.1 7.7 14.2 1.3 1 0 0 1 1 1 0 SDA1 DUF5327 PF17261.2 KEZ43514.1 - 1.6 9.5 9.4 4.7 8.0 9.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Prenylcys_lyase PF07156.14 KEZ43515.1 - 8.1e-91 304.8 0.0 1e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KEZ43515.1 - 3.7e-11 43.1 0.0 3.7e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KEZ43515.1 - 2.8e-07 30.2 0.0 5.6e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KEZ43515.1 - 1.1e-05 25.2 0.1 2.9e-05 23.8 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ43515.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KEZ43515.1 - 0.0013 18.0 0.1 0.008 15.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ43515.1 - 0.041 13.1 0.4 0.14 11.4 0.2 1.8 2 0 0 2 2 2 0 Thi4 family WSC PF01822.19 KEZ43516.1 - 6.9e-10 39.0 6.9 1.2e-09 38.2 6.9 1.4 1 0 0 1 1 1 1 WSC domain DUF4366 PF14283.6 KEZ43516.1 - 0.017 15.2 0.1 0.029 14.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Gram_pos_anchor PF00746.21 KEZ43516.1 - 0.13 12.2 2.0 0.36 10.8 2.0 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif SseC PF04888.12 KEZ43516.1 - 0.18 11.4 1.3 0.34 10.4 1.3 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ADH_N_2 PF16884.5 KEZ43517.1 - 2.8e-30 104.4 0.0 5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KEZ43517.1 - 3.5e-22 78.8 0.0 6.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ43517.1 - 4.2e-10 40.8 0.1 1e-09 39.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3681 PF12442.8 KEZ43518.1 - 0.0058 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3681) Sulfotransfer_4 PF17784.1 KEZ43519.1 - 6.4e-64 215.7 0.0 8.4e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEZ43519.1 - 0.00028 21.3 0.2 0.12 12.8 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family ECH_1 PF00378.20 KEZ43521.1 - 5.8e-41 140.5 0.0 1.1e-37 129.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ43521.1 - 7.2e-27 94.8 0.4 8.3e-23 81.4 0.1 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_trans_4_4 PF13579.6 KEZ43521.1 - 0.0042 17.6 0.5 0.044 14.2 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain GMC_oxred_C PF05199.13 KEZ43525.1 - 3.9e-28 98.8 0.0 6.8e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KEZ43525.1 - 8.4e-28 97.6 0.0 7.4e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ43525.1 - 0.00034 19.8 0.0 0.002 17.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ43525.1 - 0.00052 19.4 0.0 0.00099 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43525.1 - 0.0034 17.6 0.1 0.009 16.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KEZ43525.1 - 0.027 13.7 0.1 0.058 12.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KEZ43525.1 - 0.044 13.0 0.0 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ43525.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ43525.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 KEZ43526.1 - 1.5e-39 135.9 24.7 2.1e-39 135.4 24.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43527.1 - 3.4e-119 398.7 21.0 4.1e-119 398.4 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43527.1 - 5.1e-24 84.9 43.5 2.4e-21 76.1 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ43527.1 - 0.00014 20.9 7.0 0.058 12.2 1.0 2.6 2 1 1 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 KEZ43527.1 - 0.00019 20.1 15.8 0.035 12.7 4.6 2.7 2 0 0 2 2 2 2 MFS/sugar transport protein Cutinase PF01083.22 KEZ43528.1 - 1.5e-38 132.5 0.0 2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KEZ43528.1 - 0.00027 20.6 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KEZ43528.1 - 0.0064 16.4 0.0 0.0094 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 KEZ43528.1 - 0.041 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 KEZ43528.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) DUF4360 PF14273.6 KEZ43529.1 - 1.4e-14 54.3 0.2 1.6e-14 54.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pentaxin PF00354.17 KEZ43529.1 - 0.015 15.0 0.2 0.022 14.5 0.2 1.2 1 0 0 1 1 1 0 Pentaxin family zf-C2H2_2 PF12756.7 KEZ43530.1 - 1.3e-28 99.2 2.4 9.3e-24 83.7 0.2 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KEZ43530.1 - 0.0021 18.3 2.2 0.06 13.7 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KEZ43530.1 - 0.003 17.5 1.4 0.003 17.5 1.4 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KEZ43530.1 - 0.007 16.7 1.6 0.032 14.6 1.6 2.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KEZ43530.1 - 0.01 16.6 10.9 0.26 12.2 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger DUF629 PF04780.12 KEZ43530.1 - 0.04 12.5 0.7 1.1 7.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Ribosomal_L34e PF01199.18 KEZ43530.1 - 0.31 11.4 2.4 0.45 10.8 0.1 2.4 2 1 0 2 2 2 0 Ribosomal protein L34e zf-C2H2 PF00096.26 KEZ43530.1 - 6.7 7.4 15.4 1.6 9.3 1.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sec7 PF01369.20 KEZ43531.1 - 3e-27 95.5 0.0 6.7e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KEZ43531.1 - 1.7e-18 67.1 0.0 6.4e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF1524 PF07510.11 KEZ43532.1 - 8.6e-09 35.4 0.0 1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KEZ43532.1 - 0.16 11.9 0.0 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease Choline_kinase PF01633.20 KEZ43533.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4325 PF14213.6 KEZ43533.1 - 0.059 13.1 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Glyco_hydro_16 PF00722.21 KEZ43534.1 - 9.2e-43 145.7 0.5 2e-42 144.7 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SOG2 PF10428.9 KEZ43534.1 - 0.44 9.7 10.6 0.59 9.3 10.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1180 PF06679.12 KEZ43534.1 - 4.5 7.7 8.8 8.5 6.8 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Apt1 PF10351.9 KEZ43534.1 - 7.2 5.4 13.0 9.6 4.9 13.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KEZ43534.1 - 8.5 4.8 14.6 11 4.4 14.6 1.0 1 0 0 1 1 1 0 Macoilin family PAP2 PF01569.21 KEZ43535.1 - 4.2e-26 91.3 1.4 4.2e-26 91.3 1.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KEZ43535.1 - 0.00042 20.1 4.1 0.00042 20.1 4.1 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KEZ43535.1 - 0.012 16.2 2.4 0.021 15.4 0.1 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF5336 PF17270.2 KEZ43535.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Kinesin PF00225.23 KEZ43536.1 - 3.4e-82 276.0 0.0 4.8e-82 275.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ43536.1 - 3.6e-22 78.9 0.0 6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 KEZ43536.1 - 0.0053 17.0 0.0 0.025 14.8 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 KEZ43536.1 - 0.042 13.7 0.0 7.7 6.6 0.1 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KEZ43536.1 - 0.046 14.3 0.0 0.32 11.6 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain AIM24 PF01987.17 KEZ43537.1 - 1.1e-50 172.2 0.0 1.4e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 KEZ43538.1 - 5.2e-36 124.3 76.6 1.6e-28 99.7 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEZ43538.1 - 3.8e-08 32.3 12.1 3.8e-08 32.3 12.1 2.3 1 1 0 2 2 2 1 MFS/sugar transport protein Formyl_trans_N PF00551.19 KEZ43540.1 - 1.7e-35 122.4 0.0 2e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase DsbG_N PF18257.1 KEZ43540.1 - 0.04 14.0 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal Glyco_hydro_18 PF00704.28 KEZ43542.1 - 8.7e-41 140.6 0.1 1.2e-40 140.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SrfB PF07520.11 KEZ43542.1 - 0.082 10.8 0.8 0.11 10.3 0.8 1.1 1 0 0 1 1 1 0 Virulence factor SrfB DUF2474 PF10617.9 KEZ43543.1 - 0.065 13.1 0.2 0.065 13.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) MARVEL PF01284.23 KEZ43543.1 - 3.6 7.6 6.4 17 5.4 6.4 2.0 1 1 0 1 1 1 0 Membrane-associating domain DUF87 PF01935.17 KEZ43544.1 - 0.1 12.7 0.2 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain SH3BP5 PF05276.14 KEZ43544.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DivIC PF04977.15 KEZ43546.1 - 0.059 13.2 4.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.6 KEZ43546.1 - 0.16 12.1 0.8 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain OAD_gamma PF04277.13 KEZ43546.1 - 3.4 8.3 4.7 36 5.0 4.7 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ferlin_C PF16165.5 KEZ43546.1 - 8.9 6.2 5.8 7.2 6.5 1.2 2.1 2 0 0 2 2 2 0 Ferlin C-terminus Pyridoxal_deC PF00282.19 KEZ43547.1 - 6.9e-79 265.3 0.0 8.8e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KEZ43547.1 - 4e-06 26.3 0.0 5.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KEZ43547.1 - 6.7e-06 25.3 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GPP34 PF05719.11 KEZ43548.1 - 6.7e-69 232.0 0.3 8.3e-69 231.7 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SURF6 PF04935.12 KEZ43549.1 - 4.1e-52 176.9 42.8 4.1e-52 176.9 42.8 3.2 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KEZ43549.1 - 5.3e-08 33.4 1.4 5.3e-08 33.4 1.4 7.5 5 2 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 HUN PF08729.10 KEZ43550.1 - 1.4e-07 31.4 0.3 3.5e-07 30.1 0.3 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain MFS_1 PF07690.16 KEZ43551.1 - 4.6e-18 65.3 39.9 5.3e-18 65.1 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF2A PF08662.11 KEZ43552.1 - 1.6e-75 253.3 1.0 3.4e-74 248.9 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KEZ43552.1 - 0.025 15.5 2.9 49 5.0 0.0 4.7 4 1 1 5 5 5 0 WD domain, G-beta repeat Fic PF02661.18 KEZ43553.1 - 1.1e-07 32.7 0.1 1.9e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Fic/DOC family WD40 PF00400.32 KEZ43554.1 - 1.6e-22 79.3 21.0 3.5e-07 30.8 0.1 8.9 9 0 0 9 9 9 4 WD domain, G-beta repeat RelA_SpoT PF04607.17 KEZ43554.1 - 2.1e-09 37.7 0.0 4.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins ANAPC4_WD40 PF12894.7 KEZ43554.1 - 2.5e-08 34.1 0.7 0.021 15.1 0.0 5.6 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEZ43554.1 - 2.7e-07 30.7 0.0 7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 KEZ43554.1 - 3.4e-05 23.6 0.1 15 5.7 0.0 6.0 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KEZ43554.1 - 0.00018 20.6 2.4 0.34 9.8 0.0 5.1 5 2 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KEZ43554.1 - 0.00039 20.8 0.0 0.0014 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KEZ43554.1 - 0.008 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 KEZ43554.1 - 0.097 12.9 0.0 0.61 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 KEZ43554.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase UNC-93 PF05978.16 KEZ43555.1 - 3.2e-08 33.4 4.1 3.2e-08 33.4 4.1 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KEZ43555.1 - 8.9e-07 28.1 11.9 9.5e-07 28.0 8.6 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43555.1 - 1.2e-05 24.4 27.8 1.2e-05 24.4 27.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 KEZ43555.1 - 0.036 13.1 8.4 0.0066 15.5 4.6 1.6 2 0 0 2 2 2 0 PUCC protein MPC PF03650.13 KEZ43555.1 - 0.35 11.0 2.1 0.55 10.4 0.3 2.2 2 1 0 2 2 2 0 Mitochondrial pyruvate carriers DAO PF01266.24 KEZ43556.1 - 1.4e-25 90.6 0.0 1.7e-21 77.2 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ43556.1 - 0.037 13.2 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ43556.1 - 0.083 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Aldo_ket_red PF00248.21 KEZ43557.1 - 3.2e-48 164.4 0.0 1.8e-46 158.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 KEZ43559.1 - 8.1e-06 25.9 13.9 1.5e-05 25.0 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEZ43559.1 - 0.16 10.7 0.6 0.3 9.9 0.0 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pkinase PF00069.25 KEZ43561.1 - 5.1e-41 140.8 0.0 8.2e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43561.1 - 2.4e-19 69.6 0.0 4.1e-19 68.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ43561.1 - 0.0095 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEZ43561.1 - 0.024 14.0 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_4 PF13637.6 KEZ43562.1 - 3.2e-35 120.1 0.3 4.1e-10 40.0 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ43562.1 - 9.2e-30 103.1 0.0 1.3e-16 60.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ43562.1 - 2.3e-28 95.1 2.3 3.4e-05 23.9 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 KEZ43562.1 - 5.4e-28 96.2 0.2 2.3e-05 24.6 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KEZ43562.1 - 2.1e-25 88.4 0.6 1.2e-09 38.2 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Aminotran_5 PF00266.19 KEZ43563.1 - 3e-33 115.3 0.0 1.7e-31 109.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V AAA_16 PF13191.6 KEZ43565.1 - 5.6e-08 33.4 0.0 2.2e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KEZ43565.1 - 2.9e-05 24.8 0.9 0.00014 22.6 0.1 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 KEZ43565.1 - 0.0097 15.4 0.0 0.029 13.9 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KEZ43565.1 - 0.035 13.4 0.0 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VHS PF00790.19 KEZ43567.1 - 3.9e-46 156.4 0.0 1.7e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KEZ43567.1 - 4.7e-19 68.5 1.9 6.3e-19 68.1 0.2 2.2 3 0 0 3 3 3 1 GAT domain Alpha_adaptinC2 PF02883.20 KEZ43567.1 - 1.1e-18 67.6 0.0 2.4e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 KEZ43567.1 - 4.6e-07 29.3 0.0 1.5e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 GGA N-GAT domain AP3B1_C PF14796.6 KEZ43567.1 - 0.94 9.7 0.0 0.94 9.7 0.0 2.4 3 0 0 3 3 3 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Peptidase_S46 PF10459.9 KEZ43567.1 - 1.4 7.5 5.0 1.9 7.0 5.0 1.1 1 0 0 1 1 1 0 Peptidase S46 GTP_EFTU PF00009.27 KEZ43568.1 - 2.2e-32 112.2 2.2 6.2e-31 107.5 2.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KEZ43568.1 - 1e-25 89.9 0.3 2.9e-25 88.4 0.3 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KEZ43568.1 - 2.2e-10 40.6 0.1 4.5e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 KEZ43568.1 - 1.7e-07 31.0 0.0 3.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 KEZ43568.1 - 2.4e-07 31.0 0.2 0.0028 18.0 0.1 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KEZ43568.1 - 9.8e-05 22.3 1.0 0.004 17.1 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 KEZ43568.1 - 0.00026 20.8 0.1 0.00064 19.5 0.1 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KEZ43568.1 - 0.0031 17.0 0.1 0.0069 15.8 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KEZ43568.1 - 0.0048 16.4 0.1 0.011 15.3 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KEZ43568.1 - 0.032 14.4 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 KEZ43568.1 - 0.15 12.1 0.4 16 5.5 0.0 2.9 2 1 1 3 3 3 0 Dynamin family PP28 PF10252.9 KEZ43569.1 - 2.8e-27 95.0 17.5 2.8e-27 95.0 17.5 3.0 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CoA_trans PF01144.23 KEZ43571.1 - 1.6e-98 328.4 1.5 1e-59 201.6 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Nrap_D5 PF17406.2 KEZ43572.1 - 1.4e-49 168.0 1.2 5.8e-49 166.0 0.7 2.1 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KEZ43572.1 - 9.4e-49 165.1 0.5 1e-45 155.2 0.0 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 KEZ43572.1 - 8.6e-45 152.7 0.2 1.5e-44 151.9 0.2 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 KEZ43572.1 - 4.9e-41 140.3 0.0 8.7e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KEZ43572.1 - 2.8e-37 128.3 0.0 6.4e-37 127.1 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KEZ43572.1 - 6.8e-30 104.0 0.0 1.8e-29 102.7 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 Peptidase_C12 PF01088.21 KEZ43574.1 - 6.4e-59 199.2 0.0 1e-58 198.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KEZ43574.1 - 0.049 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Transglut_core2 PF13369.6 KEZ43575.1 - 9.2e-16 57.8 0.0 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KEZ43575.1 - 2.3e-09 37.7 0.0 3.9e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 KEZ43575.1 - 6.1e-08 32.4 0.4 2.1e-07 30.7 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ43575.1 - 9.4e-06 25.4 1.5 2.6e-05 24.0 1.1 2.0 2 0 0 2 2 2 1 F-box domain Cnn_1N PF07989.11 KEZ43576.1 - 1.7e-26 92.2 3.6 1.7e-26 92.2 3.6 17.0 4 3 12 16 16 14 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KEZ43576.1 - 1.8e-23 82.9 0.7 1.8e-23 82.9 0.7 5.2 6 1 0 6 6 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 KEZ43576.1 - 9.4e-06 24.7 197.4 0.0047 15.9 17.7 9.5 1 1 8 9 9 9 5 Spc7 kinetochore protein ADIP PF11559.8 KEZ43576.1 - 0.00014 22.0 12.4 0.00014 22.0 12.4 12.6 3 3 8 13 13 11 4 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 KEZ43576.1 - 0.00015 21.8 6.2 0.00015 21.8 6.2 12.0 2 2 7 11 11 10 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.11 KEZ43576.1 - 0.00036 19.6 22.1 0.00036 19.6 22.1 6.7 1 1 4 5 5 3 1 Protein of unknown function (DUF812) Fez1 PF06818.15 KEZ43576.1 - 0.00095 19.7 21.7 0.00095 19.7 21.7 9.4 1 1 8 9 9 7 3 Fez1 AAA_13 PF13166.6 KEZ43576.1 - 0.0025 16.5 16.2 0.0025 16.5 16.2 6.3 1 1 6 7 7 5 3 AAA domain TPR_MLP1_2 PF07926.12 KEZ43576.1 - 0.0027 17.8 16.9 0.0027 17.8 16.9 14.2 5 2 9 14 14 12 3 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 KEZ43576.1 - 0.0032 17.9 9.3 0.0032 17.9 9.3 13.6 4 4 9 13 13 8 2 Domain of unknown function (DUF4200) Filament PF00038.21 KEZ43576.1 - 0.0036 16.9 48.6 0.0036 16.9 48.6 10.0 1 1 6 7 7 6 2 Intermediate filament protein BRE1 PF08647.11 KEZ43576.1 - 0.0037 17.3 0.4 0.0037 17.3 0.4 14.8 3 2 9 14 14 12 4 BRE1 E3 ubiquitin ligase HMMR_N PF15905.5 KEZ43576.1 - 0.2 11.1 181.9 0.0088 15.6 4.8 9.1 1 1 5 8 8 8 0 Hyaluronan mediated motility receptor N-terminal Halo_GVPC PF05465.13 KEZ43576.1 - 4.3 7.7 16.9 5.5 7.3 0.4 6.3 6 0 0 6 6 5 0 Halobacterial gas vesicle protein C (GVPC) repeat MscS_porin PF12795.7 KEZ43576.1 - 4.7 6.7 195.4 0.015 14.9 14.3 9.1 1 1 7 9 9 7 0 Mechanosensitive ion channel porin domain Vac_Fusion PF02346.16 KEZ43576.1 - 6.4 6.5 12.7 11 5.8 1.7 4.9 5 0 0 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 Peptidase_C14 PF00656.22 KEZ43577.1 - 9e-62 209.2 0.0 1.2e-61 208.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KEZ43577.1 - 0.14 12.1 0.0 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain NACHT PF05729.12 KEZ43579.1 - 8e-10 38.9 0.0 1.7e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 KEZ43579.1 - 7.6e-07 29.6 0.0 2.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43579.1 - 7e-06 26.5 0.0 2.2e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KEZ43579.1 - 0.00035 20.0 0.1 0.0034 16.8 0.0 2.3 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 KEZ43579.1 - 0.00042 20.6 0.5 0.43 11.1 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat AAA_16 PF13191.6 KEZ43579.1 - 0.00058 20.3 0.9 0.021 15.2 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Ank_3 PF13606.6 KEZ43579.1 - 0.008 16.6 0.0 1.7 9.5 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.6 KEZ43579.1 - 0.028 14.7 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ank_5 PF13857.6 KEZ43579.1 - 0.09 13.1 0.1 0.73 10.2 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Whi5 PF08528.11 KEZ43580.1 - 2e-09 36.9 0.1 4.1e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.8 KEZ43581.1 - 9.6e-171 568.1 0.0 1.2e-170 567.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KEZ43581.1 - 0.00017 21.5 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_2 PF13574.6 KEZ43581.1 - 0.021 14.7 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KEZ43581.1 - 0.04 14.1 0.3 0.068 13.3 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KEZ43581.1 - 0.27 11.8 1.7 0.54 10.8 1.6 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDP-OH_P_transf PF01066.21 KEZ43582.1 - 3.6e-14 53.3 0.6 8.9e-14 52.0 0.6 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase tRNA-synt_2b PF00587.25 KEZ43583.1 - 9.1e-29 100.7 0.1 1e-26 94.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KEZ43583.1 - 1.4e-18 66.8 0.1 3e-18 65.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 KEZ43583.1 - 4.7e-12 45.8 0.0 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KEZ43583.1 - 2.7e-11 43.4 0.0 5.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Gar1 PF04410.14 KEZ43584.1 - 1.3e-38 132.2 0.0 1.6e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PH PF00169.29 KEZ43585.1 - 0.00021 21.7 0.1 0.00054 20.4 0.0 1.7 2 0 0 2 2 2 1 PH domain WEMBL PF05701.11 KEZ43585.1 - 0.0091 14.7 3.1 0.015 14.0 3.1 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Prominin PF05478.11 KEZ43585.1 - 0.48 8.3 0.9 0.72 7.7 0.9 1.2 1 0 0 1 1 1 0 Prominin MRP-S26 PF14943.6 KEZ43585.1 - 7.3 6.5 6.0 38 4.1 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 DUF2013 PF09431.10 KEZ43586.1 - 1.5e-51 174.2 2.7 1.5e-51 174.2 2.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) LCAT PF02450.15 KEZ43587.1 - 1.4e-104 350.4 0.0 1.7e-104 350.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Acetyltransf_1 PF00583.25 KEZ43588.1 - 6.9e-18 65.0 0.0 9.5e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ43588.1 - 1.4e-09 38.0 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ43588.1 - 4.6e-09 36.6 0.0 6.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ43588.1 - 1.8e-08 34.2 0.0 2.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KEZ43588.1 - 6e-06 26.0 0.0 7.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ43588.1 - 1.4e-05 25.8 0.0 1.9e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ43588.1 - 0.002 18.2 0.1 0.0032 17.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEZ43588.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF1917 PF08939.10 KEZ43589.1 - 5.2e-72 242.9 0.0 8.9e-72 242.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) ANAPC4_WD40 PF12894.7 KEZ43590.1 - 0.00053 20.2 0.0 0.056 13.7 0.0 3.1 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Xpo1 PF08389.12 KEZ43591.1 - 7.2e-07 29.4 1.8 0.00013 22.0 0.0 3.3 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.19 KEZ43591.1 - 3e-06 27.1 0.5 6.3e-05 22.8 0.0 3.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.22 KEZ43591.1 - 0.15 12.4 2.9 34 5.1 0.1 4.8 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.23 KEZ43591.1 - 1 9.5 5.9 0.48 10.5 0.1 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Fungal_trans_2 PF11951.8 KEZ43592.1 - 4.1e-09 35.7 0.1 1.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ43592.1 - 3e-06 27.3 11.8 3e-06 27.3 11.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pol_alpha_B_N PF08418.10 KEZ43592.1 - 0.036 14.0 1.4 0.059 13.3 1.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SR-25 PF10500.9 KEZ43592.1 - 0.083 12.5 20.2 0.14 11.7 20.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 KEZ43592.1 - 0.44 10.4 6.6 0.8 9.5 6.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family BPS1 PF05633.11 KEZ43592.1 - 0.53 9.2 3.8 1.2 8.0 3.8 1.5 1 0 0 1 1 1 0 Protein BYPASS1-related AF-4 PF05110.13 KEZ43592.1 - 0.55 8.3 13.6 0.74 7.8 13.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1635 PF07795.11 KEZ43592.1 - 0.73 9.6 4.0 1.4 8.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Sec3_C PF09763.9 KEZ43592.1 - 1 7.7 2.0 26 3.0 0.0 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec3 PAP1 PF08601.10 KEZ43592.1 - 1.1 8.9 9.0 1.6 8.4 9.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF755 PF05501.11 KEZ43592.1 - 2.4 8.5 22.1 4.5 7.6 22.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Apt1 PF10351.9 KEZ43592.1 - 2.4 6.9 5.5 3.6 6.3 5.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4674 PF15719.5 KEZ43592.1 - 4.3 7.3 11.6 7.9 6.5 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) IQCJ-SCHIP1 PF15157.6 KEZ43592.1 - 7.1 6.5 6.1 13 5.6 6.1 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Sec23_trunk PF04811.15 KEZ43594.1 - 1.5e-71 240.8 0.0 2.2e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KEZ43594.1 - 5e-24 84.1 0.1 2.9e-23 81.6 0.0 2.4 2 1 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KEZ43594.1 - 9.9e-18 64.7 0.1 2e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KEZ43594.1 - 1.1e-16 60.6 5.5 1.8e-16 59.9 5.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KEZ43594.1 - 2.4e-10 40.2 0.0 5.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KEZ43594.1 - 0.058 12.8 0.3 0.12 11.8 0.3 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 KEZ43595.1 - 3.6e-68 229.8 0.0 4.9e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43595.1 - 4.8e-32 111.3 0.0 6.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KEZ43595.1 - 0.00035 20.0 0.3 0.00058 19.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEZ43595.1 - 0.0013 17.7 0.2 0.0023 16.9 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KEZ43595.1 - 0.009 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Gag_p6 PF08705.11 KEZ43595.1 - 0.021 15.0 0.1 0.041 14.1 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 APH PF01636.23 KEZ43595.1 - 0.028 14.3 0.2 0.062 13.2 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.19 KEZ43595.1 - 0.029 14.1 0.2 0.087 12.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Seadorna_VP7 PF07387.11 KEZ43595.1 - 0.07 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TLD PF07534.16 KEZ43596.1 - 8.2e-23 81.2 0.1 3.6e-13 49.9 0.3 2.2 2 0 0 2 2 2 2 TLD Evr1_Alr PF04777.13 KEZ43597.1 - 1.3e-29 102.6 0.5 5.8e-29 100.5 0.2 1.9 2 0 0 2 2 2 1 Erv1 / Alr family TPP_enzyme_N PF02776.18 KEZ43598.1 - 1.5e-25 89.8 0.0 2.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ43598.1 - 2.1e-21 76.1 0.0 4.6e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KEZ43598.1 - 2.7e-14 53.2 0.2 6.5e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KEZ43598.1 - 0.057 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Diphthamide_syn PF01866.17 KEZ43598.1 - 0.13 11.7 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Putative diphthamide synthesis protein THUMP PF02926.17 KEZ43599.1 - 1.8e-06 28.1 0.7 7.1e-06 26.2 0.4 2.1 1 1 0 1 1 1 1 THUMP domain SGT1 PF07093.11 KEZ43600.1 - 3.8e-89 299.7 10.5 1.1e-81 275.0 0.0 2.3 1 1 1 2 2 2 2 SGT1 protein SMC_N PF02463.19 KEZ43601.1 - 1.8e-24 86.4 0.0 4.1e-24 85.2 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KEZ43601.1 - 1.3e-12 48.6 61.6 5.4e-09 36.8 33.3 5.4 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KEZ43601.1 - 4.4e-12 46.4 3.4 7.9e-12 45.6 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 KEZ43601.1 - 3.1e-07 30.5 7.4 8.6e-06 25.8 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ43601.1 - 0.0026 17.4 0.1 0.0062 16.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KEZ43601.1 - 0.0093 16.2 0.0 0.043 14.0 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit rve_3 PF13683.6 KEZ43601.1 - 0.033 14.0 0.0 0.23 11.3 0.0 2.5 1 0 0 1 1 1 0 Integrase core domain AAA_7 PF12775.7 KEZ43601.1 - 0.099 12.1 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KEZ43601.1 - 0.14 12.7 0.1 0.14 12.7 0.1 4.3 3 2 0 3 3 3 0 ABC transporter AAA_22 PF13401.6 KEZ43601.1 - 0.52 10.6 6.9 4.4 7.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain COQ9 PF08511.11 KEZ43602.1 - 7.4e-32 109.0 0.2 1.3e-31 108.1 0.2 1.4 1 0 0 1 1 1 1 COQ9 DUF3645 PF12359.8 KEZ43602.1 - 0.024 14.0 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) RRM_1 PF00076.22 KEZ43603.1 - 3.2e-46 155.0 0.0 1.7e-15 56.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KEZ43603.1 - 0.00059 19.8 0.0 0.86 9.7 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.8 KEZ43603.1 - 0.0011 19.0 0.0 15 5.7 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.10 KEZ43603.1 - 0.0017 18.0 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain PknH_C PF14032.6 KEZ43603.1 - 0.0097 15.8 0.2 22 4.9 0.0 3.1 3 0 0 3 3 3 2 PknH-like extracellular domain RRM_5 PF13893.6 KEZ43603.1 - 0.07 12.7 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YoaP PF14268.6 KEZ43603.1 - 0.66 9.5 1.5 1.8 8.2 0.0 2.5 4 0 0 4 4 4 0 YoaP-like SRP14 PF02290.15 KEZ43604.1 - 1.8e-28 98.7 0.3 3.1e-28 98.0 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Pyr_redox_2 PF07992.14 KEZ43605.1 - 3.4e-69 233.3 5.4 5.9e-69 232.5 5.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KEZ43605.1 - 3.8e-41 139.8 0.2 1.2e-40 138.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KEZ43605.1 - 1.5e-22 79.9 11.7 1.2e-20 73.9 1.6 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43605.1 - 1e-09 38.4 4.3 4.8e-06 26.7 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEZ43605.1 - 1.5e-09 37.7 9.4 4.3e-09 36.2 0.1 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KEZ43605.1 - 1.2e-08 34.5 9.8 1.4e-07 31.0 4.3 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KEZ43605.1 - 2.5e-07 30.2 11.0 5e-07 29.2 3.3 3.0 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 KEZ43605.1 - 2.4e-06 27.0 4.9 7.5e-05 22.1 0.1 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 KEZ43605.1 - 8e-06 25.3 5.7 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ43605.1 - 3.2e-05 23.3 6.5 0.043 13.1 0.6 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 KEZ43605.1 - 4.8e-05 22.7 0.6 0.12 11.5 0.1 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KEZ43605.1 - 8.1e-05 22.4 13.9 0.0065 16.1 0.7 4.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ43605.1 - 9.3e-05 21.3 16.1 0.00018 20.4 2.2 4.0 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.12 KEZ43605.1 - 0.00021 20.5 0.6 0.0034 16.5 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KEZ43605.1 - 0.0018 17.6 8.4 0.15 11.3 0.9 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 KEZ43605.1 - 3.6 8.1 8.1 7.8 7.0 1.5 2.9 2 2 0 2 2 2 0 Putative NAD(P)-binding FA_desaturase PF00487.24 KEZ43606.1 - 1.4e-24 87.4 28.0 2.1e-24 86.8 28.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KEZ43606.1 - 1.9e-11 43.9 0.0 4.4e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.8 KEZ43607.1 - 4.7e-81 270.7 7.8 4.7e-81 270.7 7.8 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KEZ43607.1 - 7.5e-45 151.5 0.0 5.7e-42 142.2 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KEZ43607.1 - 2.2e-09 37.6 2.7 8.9e-05 22.9 0.0 5.3 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 KEZ43607.1 - 1.6e-08 34.0 0.6 0.00015 21.7 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 KEZ43607.1 - 8e-08 32.5 0.7 0.014 15.4 0.3 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ43607.1 - 1.2e-05 25.6 0.1 0.015 15.7 0.0 4.1 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 KEZ43607.1 - 0.0035 17.3 0.0 0.34 11.0 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 KEZ43607.1 - 0.025 14.1 1.3 1.7 8.1 0.0 3.4 4 0 0 4 4 4 0 Tti2 family RasGEF_N_2 PF14663.6 KEZ43607.1 - 0.15 12.5 0.2 4.2 7.8 0.0 3.1 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain TPR_2 PF07719.17 KEZ43608.1 - 6.1e-24 82.2 10.7 0.0023 17.9 0.1 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ43608.1 - 3.8e-22 77.1 6.0 0.00033 20.3 0.0 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ43608.1 - 1.7e-21 76.6 7.4 1.8e-05 25.3 0.6 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat DnaJ PF00226.31 KEZ43608.1 - 2.7e-21 75.4 1.8 2.7e-21 75.4 1.8 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_9 PF13371.6 KEZ43608.1 - 1.7e-15 56.9 4.7 0.00026 21.1 0.0 5.0 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ43608.1 - 3.1e-15 55.5 8.6 0.058 14.2 0.2 6.8 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ43608.1 - 3.9e-14 51.6 5.8 0.014 15.5 0.0 8.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ43608.1 - 1e-13 50.7 1.3 0.0083 15.8 0.0 7.1 5 2 4 9 9 8 4 TPR repeat TPR_19 PF14559.6 KEZ43608.1 - 3.9e-11 43.3 2.8 0.036 14.6 0.0 5.5 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ43608.1 - 1.3e-10 40.6 2.6 0.038 14.0 0.1 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ43608.1 - 1.1e-08 34.9 0.2 0.0014 18.9 0.1 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat PknG_TPR PF16918.5 KEZ43608.1 - 3.2e-08 32.7 3.1 0.00084 18.2 0.1 2.8 2 1 1 3 3 3 2 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 KEZ43608.1 - 1.8e-07 31.3 19.5 0.54 11.0 0.1 8.6 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ43608.1 - 2.6e-07 30.8 17.9 0.26 11.6 0.2 6.6 7 2 0 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ43608.1 - 5.8e-06 26.4 6.2 0.086 13.1 0.0 5.0 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KEZ43608.1 - 0.0015 18.0 5.4 1 8.6 0.8 4.1 4 1 0 4 4 4 1 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 KEZ43608.1 - 0.0083 16.6 4.7 15 6.0 0.0 4.6 3 2 1 4 4 4 0 Alkyl sulfatase dimerisation TPR_15 PF13429.6 KEZ43608.1 - 0.016 14.5 6.1 14 4.8 0.0 4.8 2 2 2 5 5 5 0 Tetratricopeptide repeat Spore_SspJ PF09575.10 KEZ43608.1 - 0.08 13.3 0.2 3.2 8.2 0.1 3.3 3 0 0 3 3 2 0 Small spore protein J (Spore_SspJ) BTAD PF03704.17 KEZ43608.1 - 0.083 13.3 8.4 7.5 7.0 0.0 4.7 3 2 1 5 5 5 0 Bacterial transcriptional activator domain IR1-M PF12185.8 KEZ43608.1 - 0.11 12.5 0.2 0.39 10.7 0.1 2.0 2 0 0 2 2 1 0 Nup358/RanBP2 E3 ligase domain TPR_20 PF14561.6 KEZ43608.1 - 0.11 12.8 1.8 3.6 8.0 0.0 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat VWA_2 PF13519.6 KEZ43608.1 - 0.14 12.8 0.1 1.3 9.8 0.0 2.6 3 1 0 3 3 2 0 von Willebrand factor type A domain Cse1 PF08506.10 KEZ43608.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Cse1 TPR_4 PF07721.14 KEZ43608.1 - 0.42 11.4 4.4 95 4.1 0.1 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ43608.1 - 1 9.3 10.7 10 6.1 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat APG9 PF04109.16 KEZ43610.1 - 3.5e-177 590.2 8.7 1.6e-167 558.4 2.4 2.1 1 1 1 2 2 2 2 Autophagy protein Apg9 Mito_carr PF00153.27 KEZ43610.1 - 6e-34 115.9 6.8 6.8e-20 70.8 0.2 4.2 2 2 0 3 3 3 3 Mitochondrial carrier protein COG6 PF06419.11 KEZ43611.1 - 1.4e-202 674.4 5.0 1.6e-202 674.2 5.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KEZ43611.1 - 0.14 12.2 5.5 0.061 13.4 1.5 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PilJ PF13675.6 KEZ43611.1 - 0.37 10.8 5.6 6.6 6.8 0.8 3.9 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4164 PF13747.6 KEZ43611.1 - 0.98 9.7 5.4 5.8 7.3 0.1 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4164) Ribosomal_S17 PF00366.20 KEZ43612.1 - 1.5e-09 37.8 1.9 2.7e-08 33.8 1.9 2.3 1 1 0 1 1 1 1 Ribosomal protein S17 Macoilin PF09726.9 KEZ43612.1 - 0.79 8.2 27.3 1 7.8 27.3 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KEZ43612.1 - 3.2 4.7 29.1 4.2 4.4 29.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer EMG1 PF03587.14 KEZ43613.1 - 2e-12 47.2 0.0 2.5e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Exotox-A_target PF09102.10 KEZ43613.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A, targeting Cys_Met_Meta_PP PF01053.20 KEZ43614.1 - 1.1e-32 113.1 0.0 1.7e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3439 PF11921.8 KEZ43614.1 - 0.04 13.9 0.8 0.08 12.9 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DnaJ PF00226.31 KEZ43615.1 - 2.6e-24 85.1 0.3 2.6e-24 85.1 0.3 3.0 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.8 KEZ43615.1 - 5.3e-11 42.5 11.5 1.1e-09 38.3 5.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ43615.1 - 5.7e-09 36.1 7.7 1.1e-08 35.2 1.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KEZ43615.1 - 8.3e-07 29.3 6.8 0.00097 19.4 2.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KEZ43615.1 - 2.9e-06 27.7 2.2 0.065 14.1 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ43615.1 - 6.7e-05 23.1 5.3 0.024 15.1 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type ELF PF03317.13 KEZ43615.1 - 0.095 12.7 0.6 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 ELF protein PHD_4 PF16866.5 KEZ43615.1 - 0.17 12.0 2.2 13 6.0 0.5 2.5 2 0 0 2 2 2 0 PHD-finger zf-C2H2_3rep PF18868.1 KEZ43615.1 - 0.27 11.9 2.6 15 6.3 0.0 2.7 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats HNH_5 PF14279.6 KEZ43615.1 - 0.51 10.2 4.6 6.4 6.7 0.9 2.7 2 0 0 2 2 2 0 HNH endonuclease NOP19 PF10863.8 KEZ43615.1 - 0.93 9.3 7.5 0.38 10.6 2.2 2.4 1 1 0 2 2 2 0 Nucleolar protein 19 zf-C2H2_6 PF13912.6 KEZ43615.1 - 1.5 8.9 3.6 18 5.4 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KEZ43615.1 - 1.6 8.8 4.8 3.7 7.6 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger Peptidase_C54 PF03416.19 KEZ43616.1 - 1.1e-51 175.9 0.0 1.3e-29 103.5 0.0 2.2 1 1 0 2 2 2 2 Peptidase family C54 Histone PF00125.24 KEZ43617.1 - 3.6e-21 75.9 2.1 4.5e-21 75.6 2.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEZ43617.1 - 4.3e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KEZ43617.1 - 0.00025 21.5 0.0 0.00042 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KEZ43617.1 - 0.026 14.2 0.1 0.059 13.0 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KEZ43618.1 - 3.2e-21 74.8 2.2 5.6e-21 74.0 2.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KEZ43618.1 - 7.2e-17 62.0 0.0 9.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEZ43618.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2-oxoacid_dh PF00198.23 KEZ43619.1 - 2.3e-99 331.6 0.3 9.4e-61 205.2 0.2 2.3 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEZ43619.1 - 2.4e-18 65.7 3.6 1.1e-17 63.6 2.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KEZ43619.1 - 0.0052 17.5 0.6 0.7 10.6 0.1 2.6 1 1 1 2 2 2 1 HlyD family secretion protein S4_2 PF13275.6 KEZ43619.1 - 0.011 15.6 1.5 2.8 7.8 0.0 3.1 3 0 0 3 3 3 0 S4 domain DUF3614 PF12267.8 KEZ43619.1 - 0.013 16.0 5.1 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.6 KEZ43619.1 - 0.046 13.6 6.5 0.053 13.4 0.2 2.8 2 1 1 3 3 3 0 Biotin-lipoyl like GCV_H PF01597.19 KEZ43619.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein S4 PF01479.25 KEZ43619.1 - 0.062 13.0 0.8 17 5.2 0.1 2.8 2 0 0 2 2 2 0 S4 domain DUF1387 PF07139.11 KEZ43619.1 - 0.37 10.5 2.3 0.62 9.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ndc1_Nup PF09531.10 KEZ43619.1 - 4.4 5.9 5.1 5.8 5.5 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CorA PF01544.18 KEZ43621.1 - 4.7e-06 26.1 0.1 6.2e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Connexin PF00029.19 KEZ43621.1 - 0.0039 17.0 0.1 0.027 14.2 0.1 1.9 2 0 0 2 2 2 1 Connexin Mlo PF03094.15 KEZ43621.1 - 0.011 14.1 0.1 0.018 13.4 0.1 1.3 1 0 0 1 1 1 0 Mlo family DUF996 PF06195.13 KEZ43621.1 - 0.044 14.1 0.8 0.077 13.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Caudo_TAP PF02413.17 KEZ43621.1 - 0.063 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Methyltransf_25 PF13649.6 KEZ43622.1 - 1.3e-08 35.4 0.0 3.9e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ43622.1 - 1.9e-06 27.8 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ43622.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KEZ43622.1 - 0.0004 21.4 0.0 0.0025 18.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ43622.1 - 0.00043 21.0 0.0 0.002 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain AAA_lid_3 PF17862.1 KEZ43622.1 - 0.00067 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Methyltransf_11 PF08241.12 KEZ43622.1 - 0.0028 18.3 0.0 0.007 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43622.1 - 0.0035 17.2 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ43622.1 - 0.0038 16.6 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PRNT PF15174.6 KEZ43622.1 - 0.0062 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Prion-related protein testis-specific MetW PF07021.12 KEZ43622.1 - 0.04 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GCD14 PF08704.10 KEZ43622.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RisS_PPD PF16524.5 KEZ43622.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS CMAS PF02353.20 KEZ43622.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ThiJ_like PF17124.5 KEZ43622.1 - 0.18 11.5 0.1 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 ThiJ/PfpI family-like DUF4396 PF14342.6 KEZ43623.1 - 1.7e-45 154.9 6.6 2.5e-45 154.3 6.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) ADH_N PF08240.12 KEZ43624.1 - 1.5e-20 73.0 0.5 1.5e-20 73.0 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ43624.1 - 3.5e-16 59.4 0.3 6.2e-16 58.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEZ43624.1 - 1.6e-06 27.6 5.6 2.2e-06 27.1 4.0 2.0 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KEZ43624.1 - 0.00012 21.4 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEZ43624.1 - 0.0028 17.6 0.7 0.0043 17.0 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KEZ43624.1 - 0.011 15.5 0.3 0.011 15.5 0.3 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase LIM PF00412.22 KEZ43624.1 - 0.02 15.1 0.5 0.044 14.0 0.5 1.5 1 0 0 1 1 1 0 LIM domain ApbA PF02558.16 KEZ43624.1 - 0.027 14.1 0.4 0.042 13.5 0.4 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KEZ43624.1 - 0.078 13.2 0.5 0.18 12.0 0.5 1.7 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 KEZ43624.1 - 0.15 11.2 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Sulfatase PF00884.23 KEZ43625.1 - 2e-65 221.2 0.0 4.1e-65 220.2 0.0 1.5 2 0 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 KEZ43625.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KEZ43625.1 - 0.041 14.6 0.7 1.1 9.9 0.3 2.6 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 KEZ43625.1 - 0.065 12.8 0.0 7.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KEZ43625.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function MIase PF02426.16 KEZ43625.1 - 0.16 12.1 0.0 25 5.1 0.0 2.6 2 0 0 2 2 2 0 Muconolactone delta-isomerase DUF229 PF02995.17 KEZ43625.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) SNARE PF05739.19 KEZ43625.1 - 0.2 11.7 0.2 0.4 10.7 0.2 1.4 1 0 0 1 1 1 0 SNARE domain Sugar_tr PF00083.24 KEZ43626.1 - 9.8e-77 258.7 21.1 1.2e-76 258.5 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43626.1 - 2.5e-14 53.0 20.2 2.5e-14 53.0 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPP_enzyme_N PF02776.18 KEZ43627.1 - 4.6e-36 124.0 0.0 1.3e-35 122.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ43627.1 - 3.9e-22 78.5 0.0 7.4e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KEZ43627.1 - 5.2e-22 78.3 1.0 2e-21 76.4 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans PF04082.18 KEZ43627.1 - 2.6e-06 26.7 0.0 5.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transketolase_N PF00456.21 KEZ43627.1 - 0.12 11.3 0.0 0.26 10.2 0.0 1.5 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Urb2 PF10441.9 KEZ43627.1 - 0.14 12.1 0.3 0.26 11.2 0.3 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family Ldh_1_N PF00056.23 KEZ43628.1 - 5.1e-46 156.3 0.1 7.3e-46 155.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KEZ43628.1 - 5.9e-24 84.9 0.0 1.4e-23 83.7 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.21 KEZ43628.1 - 0.0024 17.3 0.5 0.0042 16.5 0.5 1.3 1 0 0 1 1 1 1 ThiF family Glyco_hydro_4 PF02056.16 KEZ43628.1 - 0.004 16.7 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.14 KEZ43628.1 - 0.0049 16.5 0.6 0.0085 15.7 0.1 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KEZ43628.1 - 0.023 15.3 0.2 0.045 14.3 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 KEZ43628.1 - 0.028 13.8 0.3 0.039 13.4 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.6 KEZ43628.1 - 0.052 14.0 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KEZ43628.1 - 0.079 13.2 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KEZ43628.1 - 0.1 12.1 2.8 0.2 11.2 2.8 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase DUF5436 PF17504.2 KEZ43628.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5436) 2-Hacid_dh_C PF02826.19 KEZ43628.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KEZ43628.1 - 0.17 11.7 0.4 0.34 10.8 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.12 KEZ43629.1 - 2e-28 98.4 0.4 3.2e-28 97.8 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ43629.1 - 1.2e-24 86.7 0.2 2e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ43629.1 - 0.00051 21.1 0.0 0.00085 20.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ43629.1 - 0.0031 16.9 0.2 0.0051 16.2 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KEZ43629.1 - 0.028 13.9 0.8 0.05 13.1 0.8 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 KEZ43629.1 - 0.043 13.1 0.4 0.07 12.4 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glucokinase PF02685.16 KEZ43629.1 - 0.047 12.7 0.2 0.069 12.1 0.2 1.2 1 0 0 1 1 1 0 Glucokinase HET PF06985.11 KEZ43630.1 - 1.6e-27 96.7 0.2 2.5e-27 96.0 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KEZ43631.1 - 9.3e-100 327.4 19.0 2.9e-17 63.0 0.1 9.6 3 3 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43631.1 - 7.4e-89 291.1 25.2 3.6e-10 40.2 0.1 14.8 7 3 8 15 15 15 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ43631.1 - 4.8e-81 265.8 32.6 9.7e-11 41.7 0.1 12.8 6 4 8 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43631.1 - 3.8e-79 251.1 27.5 3.2e-05 24.0 0.0 19.0 19 0 0 19 19 19 14 Ankyrin repeat Ank PF00023.30 KEZ43631.1 - 7e-76 247.6 47.1 2.2e-06 27.8 0.0 18.7 18 1 1 19 19 19 13 Ankyrin repeat NACHT PF05729.12 KEZ43631.1 - 8.1e-10 38.9 0.0 2.3e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ43631.1 - 7.6e-07 29.5 0.0 2.7e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ43631.1 - 8.3e-05 23.0 1.8 0.00063 20.2 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain CDC45 PF02724.14 KEZ43631.1 - 0.016 13.6 1.9 0.028 12.7 1.9 1.4 1 0 0 1 1 1 0 CDC45-like protein SesA PF17107.5 KEZ43631.1 - 0.031 14.5 0.1 0.11 12.6 0.1 2.1 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases VWA_3_C PF18571.1 KEZ43631.1 - 0.046 13.6 3.3 3.4 7.6 0.1 4.9 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain PEGA PF08308.11 KEZ43631.1 - 0.073 13.0 0.0 2.9 7.8 0.0 3.1 3 0 0 3 3 3 0 PEGA domain Cwf_Cwc_15 PF04889.12 KEZ43631.1 - 0.09 12.5 16.3 0.014 15.1 9.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 KEZ43631.1 - 0.098 12.3 12.3 0.031 13.9 2.7 3.0 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting AAA PF00004.29 KEZ43631.1 - 0.12 12.8 0.8 0.77 10.2 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RRN3 PF05327.11 KEZ43631.1 - 0.21 10.1 6.1 0.75 8.3 4.4 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 KEZ43631.1 - 0.33 10.3 9.2 0.017 14.6 3.1 1.8 2 0 0 2 2 2 0 SDA1 PBP1_TM PF14812.6 KEZ43631.1 - 2 8.9 21.6 2.1 8.8 14.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nitro_FeMo-Co PF02579.17 KEZ43631.1 - 2.7 8.4 6.2 1.5e+02 2.8 0.0 5.3 6 1 1 7 7 6 0 Dinitrogenase iron-molybdenum cofactor Abhydrolase_3 PF07859.13 KEZ43632.1 - 4.2e-25 88.9 0.0 6.3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEZ43632.1 - 3.8e-22 78.7 0.0 4.9e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KEZ43632.1 - 0.0058 15.9 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEZ43632.1 - 0.02 14.4 0.1 0.073 12.5 0.0 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family PMP1_2 PF08114.11 KEZ43633.1 - 0.11 12.2 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 ATPase proteolipid family Syntaxin_2 PF14523.6 KEZ43634.1 - 0.14 12.6 0.4 0.3 11.5 0.4 1.5 1 0 0 1 1 1 0 Syntaxin-like protein Tho2 PF11262.8 KEZ43634.1 - 0.16 11.1 0.4 0.27 10.4 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CAF1A PF12253.8 KEZ43634.1 - 8.1 6.7 13.9 0.44 10.8 0.3 3.5 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A Pkinase PF00069.25 KEZ43635.1 - 2.9e-33 115.4 0.0 7.5e-33 114.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43635.1 - 3.6e-08 33.0 0.1 9.1e-06 25.1 0.1 3.5 2 1 0 2 2 2 1 Protein tyrosine kinase DUF4926 PF16277.5 KEZ43635.1 - 0.091 12.1 0.3 0.2 11.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) APH PF01636.23 KEZ43635.1 - 0.1 12.5 0.3 0.9 9.4 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lipase_GDSL_2 PF13472.6 KEZ43636.1 - 6.4e-21 75.5 0.0 1.3e-20 74.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Arrestin_C PF02752.22 KEZ43636.1 - 9.3e-09 35.8 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Lipase_GDSL PF00657.22 KEZ43636.1 - 1.9e-07 31.2 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Arrestin_N PF00339.29 KEZ43636.1 - 2.2e-06 27.8 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KEZ43636.1 - 0.00056 19.7 0.0 0.0021 17.8 0.0 2.0 2 1 0 2 2 2 1 Arrestin_N terminal like Lipase_GDSL_3 PF14606.6 KEZ43636.1 - 0.00099 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Podoplanin PF05808.11 KEZ43636.1 - 0.037 14.1 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Podoplanin CFEM PF05730.11 KEZ43636.1 - 1.5 9.0 6.3 3.1 8.0 6.3 1.5 1 0 0 1 1 1 0 CFEM domain 7TM_GPCR_Str PF10326.9 KEZ43637.1 - 0.00035 20.0 1.6 0.00035 20.0 1.6 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Str DUF5445 PF17520.2 KEZ43637.1 - 0.18 11.7 0.1 0.4 10.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5445) HemY_N PF07219.13 KEZ43637.1 - 1.9 8.7 5.0 0.75 10.0 0.2 2.5 2 0 0 2 2 2 0 HemY protein N-terminus DnaJ PF00226.31 KEZ43638.1 - 2.2e-21 75.7 1.5 1.7e-20 72.9 1.5 2.6 1 0 0 1 1 1 1 DnaJ domain T3SS_needle_F PF09392.10 KEZ43638.1 - 0.065 13.4 4.7 0.068 13.4 0.1 3.2 3 1 1 4 4 4 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Rubredoxin_2 PF18073.1 KEZ43638.1 - 4 7.3 9.3 0.06 13.1 2.1 1.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain HET PF06985.11 KEZ43639.1 - 9.2e-30 103.9 0.1 2.3e-29 102.7 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DLH PF01738.18 KEZ43639.1 - 7.9e-12 45.2 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF1338 PF07063.13 KEZ43640.1 - 7.8e-109 363.8 0.0 1.1e-108 363.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Zn_clus PF00172.18 KEZ43640.1 - 1.2e-09 38.1 6.5 2.3e-09 37.2 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 KEZ43641.1 - 6.4e-22 77.9 0.0 4.7e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ43641.1 - 4e-14 53.8 0.0 7.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ43641.1 - 1.3e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KEZ43641.1 - 0.00034 20.5 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase COesterase PF00135.28 KEZ43642.1 - 1.8e-32 112.9 0.0 2.4e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_3 PF01494.19 KEZ43643.1 - 9.3e-08 31.7 0.0 1.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KEZ43643.1 - 0.0055 15.8 0.0 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Fructosamin_kin PF03881.14 KEZ43644.1 - 3e-33 115.3 0.0 3.9e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEZ43644.1 - 3.4e-05 23.9 0.0 4.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FGGY_N PF00370.21 KEZ43645.1 - 1.2e-62 211.7 0.0 1.6e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KEZ43645.1 - 4.4e-54 183.2 5.2 1.5e-52 178.2 5.2 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Zn_clus PF00172.18 KEZ43646.1 - 1.1e-07 31.9 11.1 2.6e-07 30.6 11.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ43646.1 - 2.1e-07 30.3 0.0 4.9e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 KEZ43647.1 - 2.4e-31 108.9 0.0 3.5e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ43647.1 - 3.5e-07 30.8 0.0 1.3e-05 25.6 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_3 PF17862.1 KEZ43647.1 - 4.9e-07 29.5 0.1 9.9e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KEZ43647.1 - 7.2e-06 26.3 0.0 0.0025 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ43647.1 - 0.00032 20.9 0.0 0.00067 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEZ43647.1 - 0.00035 20.6 0.0 0.00063 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEZ43647.1 - 0.00036 20.3 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KEZ43647.1 - 0.00043 20.3 0.0 0.0045 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KEZ43647.1 - 0.0022 17.7 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEZ43647.1 - 0.0028 16.9 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase PF06745.13 KEZ43647.1 - 0.0046 16.3 0.0 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 KaiC Sigma54_activ_2 PF14532.6 KEZ43647.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KEZ43647.1 - 0.0058 16.4 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KEZ43647.1 - 0.0058 17.2 0.0 0.011 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain SF3a60_bindingd PF12108.8 KEZ43647.1 - 0.0071 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Mg_chelatase PF01078.21 KEZ43647.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KEZ43647.1 - 0.0092 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KEZ43647.1 - 0.011 15.0 0.1 0.037 13.2 0.0 1.8 1 1 1 2 2 2 0 TIP49 P-loop domain TniB PF05621.11 KEZ43647.1 - 0.014 14.8 0.0 0.06 12.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 KEZ43647.1 - 0.015 15.1 0.0 0.045 13.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 KEZ43647.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 KEZ43647.1 - 0.044 13.3 0.0 0.088 12.3 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KEZ43647.1 - 0.044 13.6 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ43647.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 KEZ43647.1 - 0.083 12.3 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase ATPase_2 PF01637.18 KEZ43647.1 - 0.085 12.8 0.0 1.5 8.7 0.0 2.1 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KEZ43647.1 - 0.086 13.2 0.1 0.31 11.4 0.1 1.8 2 1 0 2 2 1 0 AAA domain TsaE PF02367.17 KEZ43647.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KEZ43647.1 - 0.16 11.1 0.0 0.36 9.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Ank_2 PF12796.7 KEZ43648.1 - 2.5e-95 313.2 3.5 2.2e-17 63.4 0.0 6.7 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43648.1 - 7.5e-76 249.6 16.9 1.6e-11 44.4 0.1 9.0 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43648.1 - 3.4e-67 214.4 3.0 0.00025 21.2 0.0 13.3 13 0 0 13 13 13 13 Ankyrin repeat Ank PF00023.30 KEZ43648.1 - 2.6e-65 214.2 14.5 0.00014 22.2 0.0 13.3 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 KEZ43648.1 - 1.2e-57 191.2 11.5 1.7e-06 28.2 0.4 13.1 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Clr5 PF14420.6 KEZ43648.1 - 1.4e-11 44.4 0.4 2.8e-11 43.5 0.4 1.6 1 0 0 1 1 1 1 Clr5 domain CorA PF01544.18 KEZ43649.1 - 4.4e-05 22.9 2.8 6e-05 22.5 0.9 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HTH_37 PF13744.6 KEZ43650.1 - 0.051 13.5 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Neurensin PF14927.6 KEZ43650.1 - 0.063 13.0 0.8 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Neurensin BMFP PF04380.13 KEZ43651.1 - 0.035 14.6 1.1 0.035 14.6 1.1 2.1 3 0 0 3 3 3 0 Membrane fusogenic activity PLDc_N PF13396.6 KEZ43652.1 - 3.9e-12 45.9 4.8 6.7e-12 45.1 4.8 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF2207 PF09972.9 KEZ43652.1 - 0.019 13.7 0.6 0.021 13.6 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MSP1a PF11670.8 KEZ43652.1 - 0.031 13.6 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Otopetrin PF03189.13 KEZ43652.1 - 0.038 12.8 0.7 0.042 12.7 0.1 1.3 1 1 0 1 1 1 0 Otopetrin DUF4199 PF13858.6 KEZ43652.1 - 0.05 14.0 1.7 0.08 13.3 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) MARVEL PF01284.23 KEZ43652.1 - 0.07 13.2 2.0 0.086 12.9 2.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF3951 PF13131.6 KEZ43652.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Glucos_trans_II PF14264.6 KEZ43652.1 - 0.16 11.3 5.1 0.11 11.9 3.6 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII Fungal_trans PF04082.18 KEZ43654.1 - 2.8e-06 26.6 0.5 4.8e-06 25.8 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ43655.1 - 9.1e-38 130.1 56.0 9.1e-38 130.1 56.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily K_trans PF02705.16 KEZ43657.1 - 4.5e-184 612.9 13.9 5.2e-184 612.7 13.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter NACHT PF05729.12 KEZ43658.1 - 3.4e-08 33.6 0.1 1.4e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 KEZ43658.1 - 3.6e-05 24.3 0.0 0.012 16.2 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ43658.1 - 0.00016 21.8 0.0 0.06 13.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat AAA_22 PF13401.6 KEZ43658.1 - 0.00018 21.8 0.1 0.0023 18.2 0.1 2.8 3 0 0 3 3 3 1 AAA domain Ank PF00023.30 KEZ43658.1 - 0.00037 20.8 0.0 0.0013 19.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat AAA_16 PF13191.6 KEZ43658.1 - 0.0017 18.8 0.1 0.01 16.2 0.1 2.5 1 0 0 1 1 1 1 AAA ATPase domain Goodbye PF17109.5 KEZ43658.1 - 0.0019 18.6 0.8 0.79 10.2 0.0 4.1 4 0 0 4 4 4 1 fungal STAND N-terminal Goodbye domain Ank_5 PF13857.6 KEZ43658.1 - 0.011 16.1 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Mg_chelatase PF01078.21 KEZ43658.1 - 0.068 12.5 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KEZ43658.1 - 0.093 13.2 0.0 0.37 11.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_4 PF13637.6 KEZ43658.1 - 0.11 13.1 0.0 13 6.5 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) NB-ARC PF00931.22 KEZ43658.1 - 0.11 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain SNF2_N PF00176.23 KEZ43659.1 - 4.9e-43 147.2 0.0 7.7e-38 130.1 0.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain zf-RING_5 PF14634.6 KEZ43659.1 - 0.00023 21.1 2.5 0.00023 21.1 2.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEZ43659.1 - 0.00077 19.4 1.4 0.00077 19.4 1.4 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KEZ43659.1 - 0.0021 17.9 2.1 0.0021 17.9 2.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEZ43659.1 - 0.005 17.1 3.6 0.013 15.8 3.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KEZ43659.1 - 0.011 15.9 1.8 0.036 14.2 1.8 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SWI2_SNF2 PF18766.1 KEZ43659.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase zf-UDP PF14569.6 KEZ43659.1 - 0.046 13.8 2.3 0.11 12.6 2.3 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger ResIII PF04851.15 KEZ43659.1 - 0.13 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KEZ43659.1 - 2.2 8.2 11.3 0.066 13.1 4.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 KEZ43659.1 - 2.3 8.3 6.8 5.7 7.1 5.7 2.3 2 1 0 2 2 1 0 Double zinc ribbon zf-RING_4 PF14570.6 KEZ43659.1 - 4.4 7.2 11.2 0.38 10.6 6.0 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 KEZ43659.1 - 5.1 7.0 8.0 1.3 9.0 4.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KEZ43659.1 - 5.8 7.1 5.5 4.3 7.5 2.6 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF2427 PF10348.9 KEZ43660.1 - 3.2e-08 33.3 2.1 7.9e-08 32.0 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KEZ43660.1 - 6.8e-08 32.7 11.0 6.8e-08 32.7 11.0 1.8 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KEZ43660.1 - 0.0014 18.8 14.7 0.015 15.5 6.3 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF4079) Peptidase_U4 PF03419.13 KEZ43660.1 - 0.32 10.2 6.1 1.5 8.1 6.1 1.9 1 1 0 1 1 1 0 Sporulation factor SpoIIGA SdpI PF13630.6 KEZ43660.1 - 1.7 8.8 17.3 0.19 11.9 2.7 3.0 2 1 1 3 3 3 0 SdpI/YhfL protein family APH PF01636.23 KEZ43661.1 - 6.4e-08 32.8 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pellino PF04710.14 KEZ43663.1 - 0.035 12.8 0.1 0.042 12.5 0.1 1.1 1 0 0 1 1 1 0 Pellino Glyco_hydro_18 PF00704.28 KEZ43665.1 - 1.1e-42 146.9 0.0 1.9e-42 146.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEZ43665.1 - 3.5e-06 27.4 7.7 3.5e-06 27.4 7.7 2.7 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 KEZ43665.1 - 1.5e-05 24.9 0.0 0.15 12.1 0.0 3.1 2 0 0 2 2 2 2 LysM domain BNR PF02012.20 KEZ43666.1 - 0.68 10.2 2.6 7.6 7.0 0.3 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat F-box-like PF12937.7 KEZ43667.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 F-box-like Kinesin PF00225.23 KEZ43668.1 - 1.3e-59 201.8 0.0 2e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ43668.1 - 2.9e-11 43.5 0.0 4.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Fungal_trans_2 PF11951.8 KEZ43669.1 - 4.5e-10 38.9 3.8 1.1e-09 37.6 3.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ43669.1 - 1.1e-05 25.4 9.3 1.1e-05 25.4 9.3 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEZ43670.1 - 5e-27 94.8 27.9 5e-27 94.8 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3082 PF11282.8 KEZ43671.1 - 0.12 12.7 2.3 0.2 11.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) COX14 PF14880.6 KEZ43671.1 - 0.41 10.5 4.0 4.6 7.2 2.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c assembly VIT1 PF01988.19 KEZ43672.1 - 1.5e-27 96.8 0.1 2.3e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 VIT family Phosphoesterase PF04185.14 KEZ43673.1 - 1.1e-34 120.2 0.6 1.5e-33 116.5 0.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family DUF4419 PF14388.6 KEZ43674.1 - 5.5e-70 236.2 0.0 2.7e-69 233.9 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) RRM_1 PF00076.22 KEZ43674.1 - 5.7e-21 74.1 0.0 6.9e-14 51.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ43674.1 - 0.00099 18.7 0.0 0.0048 16.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF478 PF04334.12 KEZ43674.1 - 0.17 11.9 0.3 0.42 10.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF478) Peptidase_M20 PF01546.28 KEZ43677.1 - 9.9e-08 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ43677.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain SesA PF17107.5 KEZ43678.1 - 5.9e-06 26.5 1.6 5.9e-06 26.5 1.6 2.6 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KEZ43678.1 - 1.2e-05 25.3 0.4 7.7e-05 22.7 0.4 2.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ43678.1 - 5.1e-05 23.7 1.7 0.00029 21.3 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ43678.1 - 0.00046 20.5 0.1 0.058 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KEZ43678.1 - 0.0037 17.0 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KEZ43678.1 - 0.0095 16.5 0.2 0.042 14.4 0.2 2.1 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.18 KEZ43678.1 - 0.0097 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KEZ43678.1 - 0.025 14.3 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ43678.1 - 0.036 14.0 0.2 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 KEZ43678.1 - 0.045 14.3 0.0 0.21 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEZ43678.1 - 0.05 12.8 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain Helo_like_N PF17111.5 KEZ43678.1 - 0.1 12.0 13.7 3.5 7.0 0.0 3.4 3 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins DUF927 PF06048.11 KEZ43678.1 - 0.14 11.7 1.6 1.4 8.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF927) RNA_helicase PF00910.22 KEZ43678.1 - 0.19 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 KEZ43678.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.0 2 1 0 2 2 1 0 AAA domain OmpH PF03938.14 KEZ43678.1 - 1.7 9.0 5.0 17 5.8 5.0 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 KEZ43678.1 - 7.9 6.5 12.0 1.3 9.1 0.9 3.5 2 1 1 3 3 3 0 Helicase HerA, central domain Methyltransf_2 PF00891.18 KEZ43679.1 - 3.1e-18 65.9 0.0 5.6e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KEZ43680.1 - 2.1e-18 66.7 0.0 3.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ43680.1 - 1e-09 39.0 0.0 2.5e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ43680.1 - 3.5e-08 34.0 0.0 6.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ43680.1 - 9e-06 26.4 0.0 5.3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43680.1 - 0.00012 21.9 0.0 0.0021 17.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ43680.1 - 0.002 17.6 0.0 0.0096 15.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KEZ43680.1 - 0.006 15.9 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KEZ43680.1 - 0.035 13.4 0.0 0.23 10.8 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KEZ43680.1 - 0.058 12.7 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 KEZ43680.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain APH PF01636.23 KEZ43681.1 - 3.1e-12 46.9 0.0 6.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ43681.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase GrpB PF04229.14 KEZ43681.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 GrpB protein DUF676 PF05057.14 KEZ43682.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ43682.1 - 0.0017 19.0 0.0 0.0042 17.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family NACHT PF05729.12 KEZ43682.1 - 0.034 14.1 0.1 0.65 9.9 0.1 2.5 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KEZ43682.1 - 0.039 14.3 0.0 0.33 11.3 0.0 2.6 3 1 0 3 3 3 0 AAA ATPase domain Palm_thioest PF02089.15 KEZ43682.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase AAA_18 PF13238.6 KEZ43682.1 - 0.11 13.0 0.0 2.7 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain LCAT PF02450.15 KEZ43682.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HET PF06985.11 KEZ43683.1 - 1.1e-37 129.6 1.2 1.9e-37 128.9 1.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 KEZ43683.1 - 0.003 17.9 0.1 10 7.0 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KEZ43683.1 - 0.0052 17.1 0.0 14 6.1 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DAO PF01266.24 KEZ43684.1 - 8.1e-31 107.9 0.1 9.6e-31 107.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ43684.1 - 1.1e-05 25.5 0.2 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KEZ43684.1 - 0.00071 18.9 0.0 0.45 9.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43684.1 - 0.0011 19.1 0.0 0.0035 17.5 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ43684.1 - 0.0014 17.9 0.1 0.53 9.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ43684.1 - 0.0054 15.9 0.3 0.016 14.3 0.1 1.8 2 1 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KEZ43684.1 - 0.039 13.0 0.2 6.1 5.8 0.1 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KEZ43684.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 KEZ43685.1 - 2.4e-32 112.2 27.4 2.4e-32 112.2 27.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.21 KEZ43686.1 - 6e-70 236.4 0.4 3.4e-69 234.0 0.4 2.0 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.18 KEZ43686.1 - 1.3e-13 50.6 0.0 2.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IU_nuc_hydro PF01156.19 KEZ43687.1 - 5.3e-20 72.2 0.0 6.9e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2457 PF10446.9 KEZ43689.1 - 0.006 15.8 20.2 0.0092 15.2 20.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SDA1 PF05285.12 KEZ43689.1 - 0.009 15.5 16.9 0.012 15.0 16.9 1.1 1 0 0 1 1 1 1 SDA1 Adeno_E3_CR2 PF02439.15 KEZ43689.1 - 0.043 13.6 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Apt1 PF10351.9 KEZ43689.1 - 0.11 11.3 3.4 0.13 11.1 3.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIF_alpha PF05793.12 KEZ43689.1 - 0.12 10.9 20.6 0.16 10.5 20.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KEZ43689.1 - 0.16 10.2 19.9 0.2 9.8 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KEZ43689.1 - 0.23 10.8 21.1 0.31 10.3 21.1 1.1 1 0 0 1 1 1 0 BUD22 Lin-8 PF03353.15 KEZ43689.1 - 1.6 8.2 6.3 2.2 7.8 6.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TEX19 PF15553.6 KEZ43689.1 - 5.1 7.0 6.6 11 6.0 6.6 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF4746 PF15928.5 KEZ43689.1 - 8.7 5.7 7.8 12 5.2 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ank_2 PF12796.7 KEZ43690.1 - 5.2e-10 39.8 0.4 0.13 12.9 0.2 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43690.1 - 5.7e-05 23.6 4.9 0.052 14.2 0.2 4.9 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43690.1 - 6.1e-05 23.1 5.9 0.88 10.3 0.1 5.7 4 2 3 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KEZ43690.1 - 0.015 15.6 5.7 11 6.5 0.0 4.9 3 2 2 5 5 5 0 Ankyrin repeats (many copies) CorA PF01544.18 KEZ43691.1 - 3.4e-31 108.6 0.0 4.5e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Palm_thioest PF02089.15 KEZ43692.1 - 0.00025 21.0 0.0 0.00044 20.2 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KEZ43692.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) RdRP PF05183.12 KEZ43695.1 - 6.8e-81 272.7 0.0 2.7e-64 217.9 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase AAA_11 PF13086.6 KEZ43695.1 - 3.7e-43 148.2 0.8 7.6e-22 78.3 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 KEZ43695.1 - 2.4e-30 105.6 0.3 3.6e-25 88.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KEZ43695.1 - 5.4e-14 52.3 0.1 1.4e-13 51.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ43695.1 - 8.5e-14 52.1 0.2 1.9e-13 51.0 0.2 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KEZ43695.1 - 3.1e-07 30.4 0.1 4.3e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KEZ43695.1 - 2.2e-06 27.8 0.0 7.2e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KEZ43695.1 - 6.6e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KEZ43695.1 - 6.8e-05 22.5 0.1 0.00039 20.1 0.1 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 KEZ43695.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase BACK PF07707.15 KEZ43695.1 - 0.00023 21.2 0.3 0.00079 19.5 0.3 1.9 1 0 0 1 1 1 1 BTB And C-terminal Kelch UvrD_C_2 PF13538.6 KEZ43695.1 - 0.00032 20.5 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KEZ43695.1 - 0.0011 18.5 0.1 0.01 15.3 0.1 2.2 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.29 KEZ43695.1 - 0.029 14.8 0.5 0.14 12.6 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 KEZ43695.1 - 0.032 14.2 0.9 2.6 8.0 0.1 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain DUF2540 PF10802.8 KEZ43695.1 - 0.055 13.6 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) AAA_22 PF13401.6 KEZ43695.1 - 0.09 13.0 0.2 0.45 10.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain Nucleos_tra2_C PF07662.13 KEZ43696.1 - 9.4e-71 237.9 4.5 9.4e-71 237.9 4.5 3.0 3 0 0 3 3 3 2 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KEZ43696.1 - 2.3e-19 69.8 5.5 2.3e-19 69.8 5.5 3.0 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Mobilization_B PF17511.2 KEZ43696.1 - 0.2 12.0 2.0 0.33 11.3 0.2 2.2 2 0 0 2 2 2 0 Mobilization protein B HET PF06985.11 KEZ43698.1 - 3.7e-10 40.3 0.0 5.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VirB7 PF17413.2 KEZ43699.1 - 0.06 12.7 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 Ank_2 PF12796.7 KEZ43700.1 - 9.2e-29 99.9 0.1 9.7e-10 38.9 0.6 5.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.25 KEZ43700.1 - 2.9e-23 82.6 0.0 4.7e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 KEZ43700.1 - 3.6e-20 69.9 10.4 0.00046 20.4 0.0 9.9 10 0 0 10 10 9 4 Ankyrin repeat Pkinase_Tyr PF07714.17 KEZ43700.1 - 4.2e-20 72.1 0.0 7.3e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 KEZ43700.1 - 1.8e-16 60.3 6.7 2.3e-07 31.2 0.2 7.7 7 2 3 10 10 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ43700.1 - 1.1e-15 57.5 7.2 1.2e-07 31.8 0.4 5.5 5 1 1 6 6 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43700.1 - 4.1e-11 42.8 15.8 0.52 10.9 0.1 8.3 8 0 0 8 8 8 4 Ankyrin repeat Kdo PF06293.14 KEZ43700.1 - 0.00091 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.6 KEZ43700.1 - 0.0054 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 TPR repeat APH PF01636.23 KEZ43700.1 - 0.01 15.8 0.1 0.031 14.2 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ43700.1 - 0.036 12.9 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KEZ43700.1 - 0.25 10.9 0.0 0.44 10.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CorA PF01544.18 KEZ43701.1 - 4.8e-22 78.6 10.8 1.3e-17 64.0 8.7 3.0 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Sugar_tr PF00083.24 KEZ43702.1 - 9.6e-82 275.2 19.1 1.6e-81 274.5 19.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter SET PF00856.28 KEZ43702.1 - 5e-14 53.0 0.0 9e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SET domain MFS_1 PF07690.16 KEZ43702.1 - 1.9e-11 43.5 25.3 1.9e-11 43.5 25.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SAF PF08666.12 KEZ43702.1 - 0.12 13.0 0.1 0.33 11.6 0.1 1.7 1 0 0 1 1 1 0 SAF domain CBM_1 PF00734.18 KEZ43703.1 - 2.4e-06 27.4 8.9 4.7e-06 26.4 8.9 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Kelch_4 PF13418.6 KEZ43703.1 - 0.56 10.2 4.5 3.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF3180 PF11377.8 KEZ43704.1 - 0.0027 17.8 3.3 0.011 15.8 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3180) DUF4064 PF13273.6 KEZ43704.1 - 2.6 8.4 7.0 0.71 10.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ATPase_gene1 PF09527.10 KEZ43704.1 - 8.9 6.6 9.2 1.8 8.8 0.3 2.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Sod_Cu PF00080.20 KEZ43706.1 - 6.2e-12 45.9 0.1 9.5e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PAN_4 PF14295.6 KEZ43707.1 - 1.9e-06 27.6 1.9 1.9e-06 27.6 1.9 1.7 2 0 0 2 2 2 1 PAN domain PBP1_TM PF14812.6 KEZ43707.1 - 0.0026 18.1 2.7 0.0036 17.6 0.0 2.3 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SDF PF00375.18 KEZ43707.1 - 0.19 10.7 0.1 0.27 10.2 0.1 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family TFIIA PF03153.13 KEZ43707.1 - 2.3 8.1 12.5 0.045 13.7 5.5 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IMS PF00817.20 KEZ43708.1 - 3.9e-42 143.8 0.0 7.8e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KEZ43708.1 - 2.5e-11 44.3 0.0 7e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KEZ43708.1 - 0.0013 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF2970 PF11174.8 KEZ43708.1 - 0.12 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Ribosomal_L19e PF01280.20 KEZ43708.1 - 0.13 12.3 0.2 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L19e TrkH PF02386.16 KEZ43709.1 - 6.9e-74 249.1 6.5 1.5e-70 238.1 0.3 2.3 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 KEZ43709.1 - 1.5 8.8 7.9 0.16 11.9 2.0 2.5 2 0 0 2 2 2 0 Ion channel FKBP_C PF00254.28 KEZ43710.1 - 5.1e-33 113.3 0.0 9.1e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RPEL PF02755.15 KEZ43712.1 - 1.7e-16 59.3 1.7 3.1e-09 36.2 0.9 2.5 2 0 0 2 2 2 2 RPEL repeat PET117 PF15786.5 KEZ43712.1 - 0.05 13.9 1.9 0.062 13.6 0.1 2.0 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial Ank_4 PF13637.6 KEZ43713.1 - 1.9e-07 31.5 0.2 9.5e-05 22.9 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ43713.1 - 8.8e-07 29.4 0.0 2.7e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ43713.1 - 5.5e-06 26.3 0.4 1.8 9.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Helo_like_N PF17111.5 KEZ43713.1 - 2.4e-05 23.8 2.0 7.3e-05 22.2 2.0 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_5 PF13857.6 KEZ43713.1 - 5.3e-05 23.4 0.6 0.0012 19.1 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43713.1 - 0.00066 20.0 0.2 1.9 9.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat MARVEL PF01284.23 KEZ43714.1 - 3.7e-12 46.5 23.5 4.8e-12 46.1 23.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_U4 PF03419.13 KEZ43714.1 - 0.42 9.9 6.4 0.48 9.7 6.4 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF1761 PF08570.10 KEZ43714.1 - 0.5 10.6 12.4 12 6.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) DUF948 PF06103.11 KEZ43714.1 - 5 7.5 7.1 32 4.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_18 PF00704.28 KEZ43715.1 - 2.2e-61 208.3 0.0 2.5e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ANAPC4_WD40 PF12894.7 KEZ43717.1 - 8.8e-06 25.9 0.0 0.00013 22.2 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 KEZ43717.1 - 0.00013 20.4 22.3 0.00019 19.9 22.3 1.1 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.12 KEZ43717.1 - 0.0019 17.7 18.3 0.0027 17.1 18.3 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT WD40 PF00400.32 KEZ43717.1 - 0.0081 17.0 0.6 0.72 10.8 0.1 4.0 4 0 0 4 4 3 1 WD domain, G-beta repeat YqfQ PF14181.6 KEZ43717.1 - 0.029 14.6 3.7 0.061 13.5 3.7 1.5 1 0 0 1 1 1 0 YqfQ-like protein Nop14 PF04147.12 KEZ43717.1 - 0.049 11.9 22.8 0.066 11.4 22.8 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KEZ43717.1 - 0.13 10.6 25.4 0.19 10.1 25.4 1.1 1 0 0 1 1 1 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 KEZ43717.1 - 0.15 12.5 3.1 0.28 11.6 3.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 KEZ43717.1 - 0.24 11.6 3.7 0.52 10.5 3.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2828 PF11443.8 KEZ43717.1 - 0.27 9.3 1.6 0.38 8.8 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SDA1 PF05285.12 KEZ43717.1 - 0.29 10.5 29.4 0.43 10.0 29.4 1.1 1 0 0 1 1 1 0 SDA1 DREPP PF05558.12 KEZ43717.1 - 0.53 10.1 10.2 0.78 9.6 10.2 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide RR_TM4-6 PF06459.12 KEZ43717.1 - 0.56 10.0 9.0 0.86 9.4 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 KEZ43717.1 - 0.58 9.1 3.5 0.81 8.6 3.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 KEZ43717.1 - 1 8.1 7.4 1.3 7.7 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BSP_II PF05432.11 KEZ43717.1 - 1.3 8.6 24.4 0.23 11.1 19.8 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 KEZ43717.1 - 1.9 6.5 31.4 2.9 5.9 31.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Zip PF02535.22 KEZ43717.1 - 2.2 7.4 3.5 3.1 6.9 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.6 KEZ43717.1 - 2.9 7.4 8.8 4.9 6.7 8.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIF_alpha PF05793.12 KEZ43717.1 - 6.4 5.3 28.8 9.2 4.7 28.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PT PF04886.12 KEZ43718.1 - 0.002 17.6 31.9 0.002 17.6 31.9 7.6 2 1 4 6 6 6 2 PT repeat RPN2_C PF18004.1 KEZ43719.1 - 5.2e-57 192.2 2.0 9.2e-57 191.4 2.0 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KEZ43719.1 - 9e-41 136.3 16.1 7.4e-08 32.4 0.0 8.1 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KEZ43719.1 - 2.1e-22 79.3 0.1 3.6e-14 52.9 0.0 6.0 4 1 3 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 KEZ43719.1 - 1.4e-06 28.6 1.6 0.0011 19.4 0.0 5.3 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 KEZ43719.1 - 2.7e-06 27.1 0.6 1.8 9.1 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 KEZ43719.1 - 0.024 14.7 0.2 2 8.4 0.0 3.3 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF2722 PF10846.8 KEZ43719.1 - 0.13 11.2 3.9 0.19 10.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Vfa1 PF08432.10 KEZ43719.1 - 4.8 7.5 10.2 10 6.4 10.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.13 KEZ43719.1 - 7.9 6.3 13.1 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region mRNA_triPase PF02940.15 KEZ43720.1 - 3.1e-52 177.5 0.0 4.3e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain zf_C2H2_6 PF18450.1 KEZ43721.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.3 3 0 0 3 3 3 0 Zinc Finger domain Cys_rich_CPXG PF14255.6 KEZ43721.1 - 0.86 9.6 3.1 0.6 10.1 0.4 2.1 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C2H2_aberr PF17017.5 KEZ43721.1 - 1.8 8.7 4.6 7.2 6.7 4.6 1.9 1 1 0 1 1 1 0 Aberrant zinc-finger TAL_FSA PF00923.19 KEZ43723.1 - 6e-39 134.1 0.0 7.9e-39 133.7 0.0 1.2 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Myb_DNA-binding PF00249.31 KEZ43724.1 - 4e-06 26.9 0.7 1.4e-05 25.1 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEZ43724.1 - 4.8e-05 23.5 3.1 4.8e-05 23.5 3.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KEZ43724.1 - 0.0087 16.1 0.0 0.02 15.0 0.0 1.6 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sugar_tr PF00083.24 KEZ43725.1 - 1.3e-116 390.1 19.5 2.3e-116 389.3 19.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43725.1 - 5.5e-25 88.0 32.9 4.9e-20 71.7 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AhpC-TSA PF00578.21 KEZ43726.1 - 1.4e-29 102.5 0.0 2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ43726.1 - 9.8e-13 48.1 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KEZ43726.1 - 1.9e-12 46.8 0.1 3.6e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PIG-S PF10510.9 KEZ43727.1 - 5.9e-170 566.5 3.9 6.8e-170 566.3 3.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Glyco_hydro_10 PF00331.20 KEZ43728.1 - 7.3e-88 294.7 0.1 8.6e-88 294.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Peptidase_S15 PF02129.18 KEZ43729.1 - 0.011 15.3 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) XdhC_CoxI PF02625.16 KEZ43729.1 - 0.027 14.6 1.5 0.64 10.3 0.2 2.6 2 0 0 2 2 2 0 XdhC and CoxI family Abhydrolase_6 PF12697.7 KEZ43729.1 - 0.25 11.9 11.5 4.6 7.8 11.5 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family AMP-binding PF00501.28 KEZ43730.1 - 8.7e-70 235.4 0.0 1.2e-69 235.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ43730.1 - 2.8e-11 44.2 0.1 6.8e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NGP1NT PF08153.12 KEZ43732.1 - 4.6e-50 169.1 0.3 7.6e-50 168.4 0.3 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KEZ43732.1 - 1.3e-16 60.7 0.0 1.7e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ43732.1 - 2.4e-05 23.9 0.0 0.00014 21.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KEZ43732.1 - 0.0002 21.3 0.0 0.00054 19.9 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KEZ43732.1 - 0.0045 16.5 0.0 0.67 9.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEZ43732.1 - 0.0056 16.8 0.0 3.1 7.8 0.0 3.3 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 KEZ43732.1 - 0.064 12.7 0.0 0.94 8.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.13 KEZ43732.1 - 0.2 10.7 0.1 0.34 9.9 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC2_membrane PF01061.24 KEZ43733.1 - 4.9e-27 94.7 15.6 4.9e-27 94.7 15.6 2.7 2 1 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KEZ43733.1 - 4.5e-24 85.5 0.0 7.9e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KEZ43733.1 - 2.8e-07 30.0 19.5 4.3e-07 29.4 18.8 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KEZ43733.1 - 4.4e-06 26.7 0.0 0.083 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ43733.1 - 0.0072 16.0 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RecA PF00154.21 KEZ43733.1 - 0.015 14.8 0.3 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_18 PF13238.6 KEZ43733.1 - 0.02 15.4 0.0 0.058 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ43733.1 - 0.041 13.5 0.1 0.097 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ43733.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ43733.1 - 0.057 13.8 0.5 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ThrE PF06738.12 KEZ43733.1 - 0.059 12.7 4.3 0.16 11.3 4.3 1.7 1 0 0 1 1 1 0 Putative threonine/serine exporter RsgA_GTPase PF03193.16 KEZ43733.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KEZ43733.1 - 0.077 13.5 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KEZ43733.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KEZ43733.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KEZ43733.1 - 0.14 11.5 0.0 3.7 6.9 0.0 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain EGF_2 PF07974.13 KEZ43733.1 - 1.4 9.3 32.8 0.3 11.5 2.1 4.0 3 0 0 3 3 2 0 EGF-like domain Aminotran_1_2 PF00155.21 KEZ43734.1 - 9.5e-41 140.2 0.0 1.2e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KEZ43734.1 - 1.3e-06 27.6 0.0 3.5e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KEZ43734.1 - 3.5e-05 22.5 0.0 5.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KEZ43734.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KEZ43734.1 - 0.0037 16.6 0.0 0.01 15.2 0.0 1.7 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 KEZ43734.1 - 0.0039 16.0 0.0 0.0055 15.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.13 KEZ43734.1 - 0.022 13.6 0.1 0.046 12.6 0.1 1.5 1 1 0 1 1 1 0 Allinase Xrn1_D3 PF18194.1 KEZ43734.1 - 0.14 12.3 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 Asp PF00026.23 KEZ43735.1 - 1.5e-38 133.0 0.0 3.2e-37 128.6 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 KEZ43735.1 - 5.3e-06 26.3 0.0 9.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal GTP_EFTU PF00009.27 KEZ43736.1 - 6.1e-57 192.3 0.3 1.1e-56 191.4 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KEZ43736.1 - 1.5e-35 121.6 0.0 3e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KEZ43736.1 - 4.4e-33 113.2 0.0 8.8e-33 112.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KEZ43736.1 - 5e-21 74.5 0.0 1.3e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEZ43736.1 - 3.8e-12 46.4 0.0 1e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KEZ43736.1 - 2.4e-07 30.7 0.0 5.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KEZ43736.1 - 0.034 14.2 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3638 PF12340.8 KEZ43736.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Iso_dh PF00180.20 KEZ43737.1 - 1.3e-98 330.4 0.0 1.8e-98 329.9 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF423 PF04241.15 KEZ43740.1 - 2.4e-23 82.2 0.6 4.7e-23 81.2 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) FMN_red PF03358.15 KEZ43741.1 - 2.2e-06 27.5 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KEZ43741.1 - 0.0001 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KEZ43741.1 - 0.00014 22.1 0.6 0.0014 18.8 0.6 2.1 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 KEZ43741.1 - 0.067 13.4 0.0 4.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain FAD_binding_3 PF01494.19 KEZ43742.1 - 6.1e-16 58.6 0.0 1e-15 57.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ43742.1 - 2e-06 27.2 0.0 3.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43742.1 - 3.2e-05 24.1 0.0 9.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ43742.1 - 0.00037 21.0 0.0 0.00099 19.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ43742.1 - 0.00047 19.3 0.0 0.001 18.3 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 KEZ43742.1 - 0.00077 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ43742.1 - 0.002 16.9 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KEZ43742.1 - 0.0061 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KEZ43742.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KEZ43742.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KEZ43742.1 - 0.045 12.8 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KEZ43742.1 - 0.22 10.3 0.3 0.89 8.3 0.1 2.0 3 0 0 3 3 3 0 Tryptophan halogenase Peptidase_M24 PF00557.24 KEZ43743.1 - 7.1e-50 169.6 0.0 8.7e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KEZ43743.1 - 8.2e-22 77.3 7.6 1.8e-21 76.1 7.6 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KEZ43743.1 - 8.2e-05 22.6 4.5 8.2e-05 22.6 4.5 2.2 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.14 KEZ43744.1 - 1.1e-48 164.5 13.7 1.3e-48 164.3 13.7 1.0 1 0 0 1 1 1 1 Cornichon protein Pec_lyase_C PF00544.19 KEZ43745.1 - 7.3e-47 159.7 2.9 1.1e-46 159.1 2.9 1.3 1 0 0 1 1 1 1 Pectate lyase DUF600 PF04634.12 KEZ43745.1 - 0.18 11.8 0.0 0.78 9.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF600 DUF3336 PF11815.8 KEZ43746.1 - 1.3e-31 109.2 0.0 2.2e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KEZ43746.1 - 6.6e-21 75.4 0.0 1.3e-20 74.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase SLAIN PF15301.6 KEZ43746.1 - 0.001 18.4 6.9 0.002 17.5 6.9 1.4 1 0 0 1 1 1 1 SLAIN motif-containing family adh_short_C2 PF13561.6 KEZ43747.1 - 7.8e-54 182.7 0.1 1e-53 182.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43747.1 - 1e-46 158.9 0.1 1.4e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ43747.1 - 8.5e-15 55.1 0.4 1.2e-14 54.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ43747.1 - 4.1e-05 23.2 0.1 7.8e-05 22.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ43747.1 - 0.00047 19.7 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF3277 PF11681.8 KEZ43747.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Ank_2 PF12796.7 KEZ43748.1 - 1.4e-49 166.6 0.0 1.2e-13 51.4 0.0 6.3 4 1 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ43748.1 - 4.6e-36 122.4 6.0 1.2e-06 28.6 0.0 9.4 1 1 9 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43748.1 - 4.5e-33 109.5 0.1 0.0012 19.2 0.0 9.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 KEZ43748.1 - 4.6e-32 110.0 1.3 2.3e-06 28.0 0.0 6.9 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43748.1 - 1e-23 82.7 0.1 0.0051 17.2 0.0 8.3 9 0 0 9 9 9 5 Ankyrin repeat NACHT PF05729.12 KEZ43748.1 - 0.00034 20.6 0.0 0.00074 19.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ43748.1 - 0.0035 17.6 0.0 0.0086 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ43748.1 - 0.052 14.0 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KEZ43748.1 - 0.052 13.1 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ43748.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Chitin_synth_1 PF01644.17 KEZ43749.1 - 7.7e-55 185.3 0.0 1.2e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KEZ43749.1 - 1.7e-15 56.6 0.0 8.8e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KEZ43749.1 - 2.9e-13 49.6 0.5 5.5e-10 39.1 0.1 3.3 2 1 1 3 3 3 2 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KEZ43749.1 - 1.6e-05 24.9 0.1 1.6e-05 24.9 0.1 3.3 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEZ43749.1 - 0.0068 16.3 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 EPSP_synthase PF00275.20 KEZ43750.1 - 7.6e-131 436.6 0.0 1.1e-130 436.2 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KEZ43750.1 - 4.6e-101 337.4 0.6 6e-101 337.0 0.0 1.5 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KEZ43750.1 - 5.3e-56 190.4 0.0 1.1e-55 189.4 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KEZ43750.1 - 2.3e-36 125.3 0.0 2.7e-34 118.6 0.0 2.7 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 KEZ43750.1 - 3.8e-23 81.5 0.0 1.3e-22 79.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KEZ43750.1 - 3.5e-09 36.7 0.0 7.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KEZ43750.1 - 3.1e-05 23.6 0.0 8.8e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KEZ43750.1 - 0.00012 22.2 0.0 0.00045 20.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Zeta_toxin PF06414.12 KEZ43750.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 KEZ43750.1 - 0.19 11.8 0.0 0.5 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain CENP-T_C PF15511.6 KEZ43751.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KEZ43751.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KEZ43751.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KEZ43751.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KEZ43751.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KEZ43751.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KEZ43751.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KEZ43751.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KEZ43751.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 KEZ43752.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KEZ43752.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KEZ43752.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KEZ43752.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KEZ43752.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KEZ43752.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KEZ43752.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated HBB PF06777.11 KEZ43753.1 - 3e-47 160.8 0.9 3.5e-43 147.5 0.3 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KEZ43753.1 - 2.2e-44 151.6 0.0 7.9e-44 149.8 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KEZ43753.1 - 5.9e-37 127.0 4.6 7.6e-32 110.3 0.5 3.0 2 1 1 3 3 3 2 DEAD_2 ResIII PF04851.15 KEZ43753.1 - 2.5e-05 24.3 0.0 4.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ43753.1 - 4e-05 23.5 0.0 8.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KEZ43753.1 - 0.0086 14.8 0.1 0.069 11.9 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.16 KEZ43753.1 - 0.052 13.0 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KEZ43753.1 - 0.062 13.6 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KEZ43753.1 - 0.12 12.7 0.2 2.1 8.6 0.2 2.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ43753.1 - 0.16 11.2 0.0 6.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FAD_binding_3 PF01494.19 KEZ43757.1 - 1.1e-72 245.2 0.0 1.5e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEZ43757.1 - 2.6e-40 138.1 0.1 6.5e-40 136.9 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.27 KEZ43757.1 - 3.3e-05 24.3 0.0 0.0024 18.4 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ43757.1 - 0.00012 21.4 0.0 0.0068 15.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43757.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEZ43757.1 - 0.014 14.1 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 KEZ43757.1 - 0.033 13.8 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ43757.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KEZ43757.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 KEZ43757.1 - 0.16 12.4 0.0 0.56 10.7 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 KEZ43757.1 - 0.17 11.4 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KEZ43757.1 - 0.19 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Peptidase_C48 PF02902.19 KEZ43758.1 - 5.5e-19 68.9 0.0 1.2e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1682 PF07946.14 KEZ43758.1 - 0.00063 19.1 6.5 0.0012 18.1 6.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RGS PF00615.19 KEZ43759.1 - 3.6e-10 40.1 0.0 6.3e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain LigB PF02900.18 KEZ43760.1 - 3.4e-29 101.8 0.0 4.1e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DAO PF01266.24 KEZ43761.1 - 2e-52 178.9 0.0 2.9e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KEZ43761.1 - 1.4e-44 151.0 0.1 2.5e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KEZ43761.1 - 8.8e-09 34.9 0.0 1.8e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEZ43761.1 - 3.3e-05 23.4 0.1 0.00018 21.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ43761.1 - 0.0002 20.8 0.0 0.00033 20.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ43761.1 - 0.00042 19.6 0.0 0.00076 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43761.1 - 0.003 17.8 0.2 0.011 15.9 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ43761.1 - 0.01 15.0 0.1 0.044 12.9 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KEZ43761.1 - 0.017 13.8 0.2 0.026 13.2 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KEZ43761.1 - 0.03 14.9 0.2 0.083 13.5 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ43761.1 - 0.058 12.6 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KEZ43761.1 - 0.062 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KEZ43761.1 - 0.093 12.0 0.6 0.25 10.6 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Methyltransf_34 PF11312.8 KEZ43761.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase PTH2 PF01981.16 KEZ43762.1 - 4.3e-46 156.0 0.2 5.6e-46 155.6 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Hom_end PF05204.14 KEZ43762.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Homing endonuclease cobW PF02492.19 KEZ43763.1 - 2e-34 118.7 0.0 2.4e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KEZ43763.1 - 6.5e-05 22.1 0.9 0.00099 18.2 0.9 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KEZ43763.1 - 0.0042 17.2 0.0 0.015 15.4 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 KEZ43763.1 - 0.0061 17.1 0.0 0.0093 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ43763.1 - 0.047 14.1 0.0 0.065 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KEZ43763.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KEZ43763.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.4 1 1 0 1 1 1 0 NACHT domain BING4CT PF08149.11 KEZ43764.1 - 4.8e-39 132.0 0.0 1.7e-35 120.7 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KEZ43764.1 - 5.9e-05 23.3 1.3 32 4.9 0.0 5.6 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KEZ43764.1 - 0.00011 21.4 0.2 0.00035 19.7 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 KEZ43764.1 - 0.0051 17.6 0.0 1.8 9.5 0.0 3.9 4 1 1 5 5 5 1 WD domain, G-beta repeat SNAP PF14938.6 KEZ43765.1 - 2.5e-108 361.8 12.4 3.5e-108 361.3 12.4 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KEZ43765.1 - 1.2e-07 31.9 8.6 0.014 15.7 0.2 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ43765.1 - 2.1e-05 24.4 10.5 0.032 14.4 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ43765.1 - 2.3e-05 24.1 4.8 0.033 14.2 0.2 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ43765.1 - 0.00076 19.4 15.5 1.3 9.3 0.5 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat DUF2521 PF10730.9 KEZ43765.1 - 0.016 15.2 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) TPR_6 PF13174.6 KEZ43765.1 - 0.018 15.7 12.4 34 5.4 0.0 5.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ43765.1 - 0.076 12.9 13.5 3.9 7.5 1.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF732 PF05305.14 KEZ43765.1 - 3.2 8.2 7.6 15 6.0 6.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF732) NSF PF02071.20 KEZ43765.1 - 4.1 8.6 15.7 31 6.0 0.2 5.4 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat DUF726 PF05277.12 KEZ43766.1 - 1.1e-81 274.5 0.0 1.5e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PPI_Ypi1 PF07491.11 KEZ43767.1 - 1.3e-23 82.6 8.6 7.6e-23 80.1 8.6 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor SelP_N PF04592.14 KEZ43767.1 - 0.21 11.0 7.7 0.32 10.4 7.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.14 KEZ43767.1 - 0.32 9.3 6.8 0.36 9.1 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein IMUP PF15761.5 KEZ43767.1 - 2 9.2 21.2 0.75 10.5 18.3 1.9 1 1 0 1 1 1 0 Immortalisation up-regulated protein DENN PF02141.21 KEZ43768.1 - 5e-56 189.6 0.0 9e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 KEZ43768.1 - 1.2e-15 57.2 0.7 2.6e-15 56.2 0.7 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 KEZ43768.1 - 3.1e-13 50.2 0.0 7.1e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 uDENN domain PHD PF00628.29 KEZ43768.1 - 0.18 11.7 5.2 0.17 11.8 2.9 2.1 1 1 1 2 2 2 0 PHD-finger C1_2 PF03107.16 KEZ43768.1 - 0.25 11.7 5.8 0.63 10.4 5.8 1.7 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.22 KEZ43768.1 - 0.29 11.0 8.1 0.62 10.0 7.4 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 KEZ43768.1 - 4.7 7.1 7.5 10 6.0 7.5 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon MMR_HSR1 PF01926.23 KEZ43769.1 - 4.7e-05 23.4 0.0 0.31 11.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.16 KEZ43770.1 - 2.7e-13 49.6 0.1 4.2e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HECT PF00632.25 KEZ43771.1 - 3.4e-60 204.1 0.0 4.1e-33 115.2 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) OrfB_Zn_ribbon PF07282.11 KEZ43771.1 - 0.074 13.0 0.7 0.18 11.8 0.7 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_1 PF00130.22 KEZ43771.1 - 0.15 11.9 1.0 0.35 10.8 1.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_pol_Rpc82 PF05645.13 KEZ43771.1 - 0.29 10.9 2.8 0.55 9.9 2.8 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 S10_plectin PF03501.15 KEZ43772.1 - 1e-41 140.9 0.1 1.2e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain COX6B PF02297.17 KEZ43773.1 - 6.3e-19 68.0 5.9 7.7e-19 67.7 5.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KEZ43773.1 - 0.031 14.3 1.9 0.031 14.3 1.9 1.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KEZ43773.1 - 0.037 14.0 1.3 0.043 13.8 0.8 1.4 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 KEZ43773.1 - 0.096 12.3 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain B12D PF06522.11 KEZ43774.1 - 0.0059 16.4 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 KEZ43775.1 - 2.6e-18 65.6 0.0 3.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ43775.1 - 0.00017 21.6 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KEZ43775.1 - 0.0067 16.0 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEZ43775.1 - 0.009 16.0 0.0 0.028 14.4 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KEZ43775.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Gemini_BL1 PF00845.19 KEZ43775.1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Geminivirus BL1 movement protein LD_cluster3 PF18180.1 KEZ43775.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster3 family SRA1 PF07304.11 KEZ43776.1 - 2e-10 40.6 2.7 2e-10 40.6 2.7 3.9 4 2 1 5 5 5 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KEZ43776.1 - 1.7e-09 37.7 0.1 8.1e-09 35.6 0.1 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 KEZ43776.1 - 2.2e-07 31.5 0.5 0.026 15.4 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat BBS2_N PF14781.6 KEZ43776.1 - 0.057 13.3 0.0 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal PALB2_WD40 PF16756.5 KEZ43776.1 - 0.1 11.5 0.0 0.5 9.2 0.0 2.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 KEZ43777.1 - 1.4e-18 67.2 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43777.1 - 2.4e-08 33.6 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PfkB PF00294.24 KEZ43778.1 - 8e-12 45.1 0.0 1.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPR_2 PF07719.17 KEZ43779.1 - 2.9e-14 51.9 2.8 6.1e-05 22.8 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ43779.1 - 8.2e-13 47.6 0.2 5.2e-06 26.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ43779.1 - 9.9e-11 41.0 1.1 0.0017 18.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ43779.1 - 4.7e-07 30.1 6.0 0.00091 19.8 0.2 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ43779.1 - 4.5e-05 24.0 9.5 0.029 15.0 0.3 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ43779.1 - 0.00014 21.9 1.0 0.00052 20.1 0.8 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ43779.1 - 0.0003 21.0 6.4 0.34 11.2 1.8 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ43779.1 - 0.00052 20.5 0.6 7 7.5 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ43779.1 - 0.0034 17.6 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 KEZ43779.1 - 0.01 16.5 0.1 9.4 7.1 0.1 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_7 PF13176.6 KEZ43779.1 - 0.02 14.9 6.3 4.3 7.6 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ43779.1 - 0.02 15.4 3.8 0.36 11.4 0.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ43779.1 - 0.066 13.6 3.8 11 6.7 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ43779.1 - 0.091 12.5 0.5 7.2 6.4 0.1 3.3 2 1 1 3 3 3 0 TPR repeat SNAP PF14938.6 KEZ43779.1 - 0.1 12.0 3.3 0.15 11.5 2.2 1.7 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KEZ43779.1 - 0.26 11.2 4.8 17 5.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat GET2 PF08690.10 KEZ43780.1 - 1.8e-46 159.3 0.0 2.5e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 TMEM135_C_rich PF15982.5 KEZ43781.1 - 0.00015 22.3 0.1 0.00075 20.1 0.1 2.2 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 HLH PF00010.26 KEZ43782.1 - 1.3e-05 25.1 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NAM-associated PF14303.6 KEZ43782.1 - 1.7 9.3 7.0 3.1 8.5 7.0 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Gp_dh_C PF02800.20 KEZ43783.1 - 2.7e-71 238.3 0.1 4.3e-71 237.6 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KEZ43783.1 - 2.7e-39 133.6 0.1 6.6e-39 132.3 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KEZ43783.1 - 0.005 17.0 0.2 0.017 15.3 0.1 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KEZ43783.1 - 0.033 13.5 0.1 0.082 12.3 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YDG PF18657.1 KEZ43783.1 - 0.33 11.2 4.7 0.27 11.4 0.4 2.8 2 1 0 2 2 2 0 YDG domain UFD1 PF03152.14 KEZ43785.1 - 8.9e-67 223.9 0.0 1.1e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TIP49 PF06068.13 KEZ43787.1 - 2.5e-151 503.8 0.9 2.5e-151 503.8 0.9 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 KEZ43787.1 - 6.2e-23 80.7 0.3 2.4e-22 78.8 0.2 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KEZ43787.1 - 1.4e-10 41.1 0.3 9.4e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KEZ43787.1 - 5.7e-09 36.5 1.7 1.3e-05 25.7 0.1 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ43787.1 - 2.2e-07 31.4 0.3 6.2e-07 30.0 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 KEZ43787.1 - 1.9e-06 27.4 2.1 2.8e-06 26.9 0.6 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 KEZ43787.1 - 0.00034 20.1 0.9 0.0057 16.1 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEZ43787.1 - 0.00042 20.3 0.1 0.069 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEZ43787.1 - 0.001 18.7 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ43787.1 - 0.0022 18.3 0.0 0.33 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ43787.1 - 0.0074 16.5 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KEZ43787.1 - 0.011 15.5 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 KEZ43787.1 - 0.011 16.0 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ43787.1 - 0.024 15.2 0.0 0.13 12.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ43787.1 - 0.025 14.6 0.1 0.064 13.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KEZ43787.1 - 0.093 12.5 0.5 0.66 9.7 0.5 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEZ43787.1 - 0.11 12.0 0.3 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 KEZ43787.1 - 0.16 11.8 0.0 0.4 10.4 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Parvo_NS1 PF01057.17 KEZ43787.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CEP63 PF17045.5 KEZ43788.1 - 0.002 18.1 13.8 0.002 18.1 13.8 4.5 5 1 0 5 5 5 1 Centrosomal protein of 63 kDa DUF3584 PF12128.8 KEZ43788.1 - 0.0055 14.3 42.8 0.032 11.8 12.5 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) HALZ PF02183.18 KEZ43788.1 - 0.0095 16.1 0.8 0.0095 16.1 0.8 4.9 5 1 1 6 6 5 1 Homeobox associated leucine zipper YabA PF06156.13 KEZ43788.1 - 0.042 14.5 33.1 0.05 14.3 6.8 6.0 4 2 2 6 6 6 0 Initiation control protein YabA FlaC_arch PF05377.11 KEZ43788.1 - 0.05 14.0 22.9 4 7.9 0.3 6.9 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) IL3 PF02059.15 KEZ43788.1 - 0.18 11.9 3.7 1.2 9.3 2.0 2.9 2 0 0 2 2 2 0 Interleukin-3 DUF3037 PF11236.8 KEZ43788.1 - 0.2 12.1 8.7 0.32 11.4 0.0 5.1 2 2 2 6 6 6 0 Protein of unknown function (DUF3037) Spc7 PF08317.11 KEZ43788.1 - 0.22 10.4 48.4 0.26 10.1 0.8 5.5 3 3 1 5 5 5 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KEZ43788.1 - 0.27 11.8 38.6 0.37 11.4 3.5 7.7 5 2 2 7 7 7 0 Syntaxin 6, N-terminal DUF16 PF01519.16 KEZ43788.1 - 0.42 11.1 0.1 0.42 11.1 0.1 6.3 3 3 3 6 6 5 0 Protein of unknown function DUF16 Med30 PF11315.8 KEZ43788.1 - 0.64 10.2 21.4 2.4 8.3 10.2 4.1 4 0 0 4 4 4 0 Mediator complex subunit 30 APG6_N PF17675.1 KEZ43788.1 - 0.73 10.4 52.3 2.8 8.5 0.6 6.5 4 2 0 4 4 4 0 Apg6 coiled-coil region Alpha-2-MRAP_C PF06401.11 KEZ43788.1 - 3.1 7.7 17.8 13 5.7 3.3 4.5 3 1 1 4 4 4 0 Alpha-2-macroglobulin RAP, C-terminal domain Occludin_ELL PF07303.13 KEZ43788.1 - 3.9 8.2 33.2 3.3 8.5 2.8 6.4 8 0 0 8 8 6 0 Occludin homology domain LXG PF04740.12 KEZ43788.1 - 4.3 7.0 25.3 0.74 9.5 0.0 5.2 3 3 1 5 5 5 0 LXG domain of WXG superfamily Fib_alpha PF08702.10 KEZ43788.1 - 8 6.6 33.9 0.21 11.7 1.3 6.1 5 2 2 7 7 7 0 Fibrinogen alpha/beta chain family LacI PF00356.21 KEZ43789.1 - 0.085 12.7 0.3 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TFIIA PF03153.13 KEZ43790.1 - 5e-07 30.1 41.6 7.3e-07 29.5 41.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KEZ43790.1 - 0.14 10.4 36.8 0.17 10.1 36.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4770 PF15994.5 KEZ43790.1 - 7.8 6.7 18.0 15 5.8 18.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) ALMT PF11744.8 KEZ43790.1 - 9 5.0 7.4 14 4.4 7.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter XRCC4 PF06632.12 KEZ43793.1 - 2.1e-08 33.4 22.7 3.7e-07 29.3 22.7 2.0 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Rootletin PF15035.6 KEZ43793.1 - 0.0035 17.4 2.5 0.0066 16.5 2.5 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Mito_fiss_reg PF05308.11 KEZ43793.1 - 0.011 15.8 4.8 0.011 15.8 4.8 2.2 1 1 2 3 3 3 0 Mitochondrial fission regulator Arc_PepC PF06819.11 KEZ43793.1 - 0.034 14.3 0.6 0.064 13.4 0.6 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Spc7 PF08317.11 KEZ43793.1 - 0.074 11.9 4.1 0.12 11.3 4.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Arg_decarbox_C PF17944.1 KEZ43793.1 - 0.13 12.8 0.4 0.34 11.5 0.4 1.7 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension OmpH PF03938.14 KEZ43793.1 - 0.23 11.8 5.0 0.52 10.6 5.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CCDC106 PF15794.5 KEZ43793.1 - 0.52 10.0 8.7 0.036 13.8 0.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CN_hydrolase PF00795.22 KEZ43795.1 - 9e-13 48.2 0.0 2.3e-11 43.5 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Cofilin_ADF PF00241.20 KEZ43796.1 - 1.8e-39 134.3 0.5 2.1e-39 134.1 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1349 PF07081.11 KEZ43796.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1349) Blt1 PF12754.7 KEZ43797.1 - 2.9e-34 118.5 1.4 4.6e-34 117.9 0.6 1.6 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 KEZ43797.1 - 8e-15 54.2 1.5 8e-15 54.2 1.5 1.6 2 0 0 2 2 2 1 Get5 carboxyl domain ubiquitin PF00240.23 KEZ43797.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Cpn60_TCP1 PF00118.24 KEZ43798.1 - 3e-87 293.3 10.9 5.8e-87 292.4 10.9 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribonuclease_3 PF00636.26 KEZ43801.1 - 1.1e-08 35.6 0.0 5.4e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KEZ43801.1 - 4.1e-07 30.2 0.0 8.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KEZ43801.1 - 0.0017 19.0 0.0 0.0037 17.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif SOAR PF16533.5 KEZ43801.1 - 0.0053 16.7 0.2 0.0053 16.7 0.2 2.5 2 0 0 2 2 2 1 STIM1 Orai1-activating region TPR_12 PF13424.6 KEZ43802.1 - 8.1e-33 112.6 16.7 3.3e-10 40.1 0.5 5.8 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ43802.1 - 2.4e-29 100.3 13.4 0.00011 21.9 0.1 7.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ43802.1 - 2.1e-10 40.5 6.3 3.8e-09 36.4 0.6 2.5 1 1 0 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 KEZ43802.1 - 4.2e-07 30.4 10.6 0.0048 17.4 0.1 5.1 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ43802.1 - 1.1e-05 25.5 24.8 0.098 13.3 0.2 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ43802.1 - 2.3e-05 24.1 16.2 0.44 10.8 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ43802.1 - 5e-05 23.2 4.0 2.4 8.6 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ43802.1 - 7.9e-05 23.2 10.3 0.22 12.2 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ43802.1 - 9e-05 23.0 10.3 2.2 9.3 0.0 6.2 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ43802.1 - 0.0031 17.3 9.1 6.8 6.7 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ43802.1 - 0.0035 17.5 0.4 14 6.0 0.0 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 ATPase PF06745.13 KEZ43802.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC TPR_7 PF13176.6 KEZ43802.1 - 0.033 14.2 7.9 8.1 6.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat NACHT PF05729.12 KEZ43802.1 - 0.043 13.7 0.0 4.2 7.3 0.0 3.4 3 1 0 3 3 2 0 NACHT domain TPR_17 PF13431.6 KEZ43802.1 - 0.052 13.9 1.1 21 5.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ43802.1 - 0.073 13.5 0.0 0.36 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 KEZ43802.1 - 0.14 11.3 0.0 5.4 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain PPR PF01535.20 KEZ43802.1 - 0.17 12.2 1.7 13 6.3 0.0 4.5 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.6 KEZ43802.1 - 5.3 7.9 8.3 2.5e+02 2.6 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat p450 PF00067.22 KEZ43803.1 - 3.2e-57 194.3 0.0 5e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ACBP PF00887.19 KEZ43804.1 - 1.5e-24 86.0 0.7 4.4e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Acyl CoA binding protein Peptidase_S64 PF08192.11 KEZ43804.1 - 0.039 12.4 0.8 0.046 12.2 0.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 NTPase_P4 PF11602.8 KEZ43804.1 - 0.042 13.1 0.2 0.063 12.5 0.2 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 DUF2347 PF09804.9 KEZ43804.1 - 0.16 11.6 0.6 0.22 11.1 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Molybdopterin PF00384.22 KEZ43806.1 - 3.4e-67 227.3 0.0 3.2e-65 220.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KEZ43806.1 - 2.7e-20 72.2 0.2 7.8e-20 70.7 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KEZ43806.1 - 5.1e-19 68.7 0.0 1.5e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KEZ43806.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KEZ43806.1 - 5.9e-08 32.5 0.5 5.9e-08 32.5 0.5 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KEZ43806.1 - 0.1 12.3 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Aldo_ket_red PF00248.21 KEZ43807.1 - 8.5e-40 136.8 0.0 2.6e-38 131.9 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 KEZ43807.1 - 9.8e-26 90.9 0.0 1.5e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2375 PF09558.10 KEZ43807.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) MRP-S33 PF08293.11 KEZ43808.1 - 1.1e-30 105.7 0.1 1.2e-30 105.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.19 KEZ43809.1 - 1.2e-38 128.6 0.7 4.1e-06 26.2 0.0 8.7 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat EBP50_C PF09007.11 KEZ43809.1 - 0.064 14.3 2.2 0.12 13.3 2.2 1.4 1 0 0 1 1 1 0 EBP50, C-terminal RasGEF PF00617.19 KEZ43809.1 - 0.2 11.9 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 RasGEF domain DUF5572 PF17733.1 KEZ43810.1 - 6.2e-13 48.4 0.2 1.8e-12 46.9 0.2 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF3306 PF11748.8 KEZ43810.1 - 5 8.0 7.7 1.3 9.9 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) PP2C PF00481.21 KEZ43811.1 - 4.7e-41 141.1 0.0 7.9e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KEZ43811.1 - 0.0025 17.8 0.0 0.2 11.6 0.0 3.0 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) SLAC1 PF03595.17 KEZ43812.1 - 1.9e-69 234.4 46.6 2.3e-69 234.1 46.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Ribosomal_S5_C PF03719.15 KEZ43813.1 - 5.2e-22 77.1 0.0 2e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KEZ43813.1 - 1.4e-17 63.4 2.0 1.4e-17 63.4 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.10 KEZ43814.1 - 5.8e-33 112.8 0.1 6.6e-33 112.6 0.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 FliG_C PF01706.16 KEZ43814.1 - 0.09 13.0 0.2 0.11 12.7 0.2 1.1 1 0 0 1 1 1 0 FliG C-terminal domain PSP1 PF04468.12 KEZ43815.1 - 4e-28 97.5 1.2 7.4e-28 96.7 1.2 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF5094 PF17015.5 KEZ43815.1 - 0.063 13.4 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) 14-3-3 PF00244.20 KEZ43816.1 - 0.032 13.8 0.2 0.05 13.1 0.2 1.3 1 0 0 1 1 1 0 14-3-3 protein KELK PF15796.5 KEZ43816.1 - 3 8.4 12.3 3.2 8.3 2.8 2.7 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Ribosomal_L15e PF00827.17 KEZ43818.1 - 3.4e-89 297.6 9.0 4.2e-89 297.3 9.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.19 KEZ43819.1 - 8.7e-60 195.2 10.3 1.5e-07 30.7 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF445 PF04286.12 KEZ43819.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RNA_pol_Rpb2_6 PF00562.28 KEZ43820.1 - 1.6e-119 399.5 0.5 2.5e-119 398.8 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KEZ43820.1 - 1.8e-51 174.5 0.2 2.6e-51 174.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KEZ43820.1 - 4.1e-33 113.6 0.5 1.1e-32 112.3 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KEZ43820.1 - 4.1e-31 108.1 0.2 1.3e-30 106.4 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KEZ43820.1 - 4.9e-22 78.0 0.1 1.1e-21 76.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KEZ43820.1 - 2.2e-19 69.4 0.0 4.8e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KEZ43820.1 - 1.8e-09 38.0 0.5 5.5e-09 36.4 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 AAA PF00004.29 KEZ43821.1 - 3e-15 56.8 0.0 5.4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ43821.1 - 0.0018 18.7 0.0 0.0079 16.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ43821.1 - 0.025 14.9 0.3 0.078 13.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ43821.1 - 0.11 12.6 0.1 0.37 10.9 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEZ43821.1 - 0.15 12.0 0.0 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SKG6 PF08693.10 KEZ43822.1 - 0.0076 15.6 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Carn_acyltransf PF00755.20 KEZ43823.1 - 3e-200 666.8 0.0 6.2e-173 576.6 0.0 2.2 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase MFS_1 PF07690.16 KEZ43824.1 - 2.4e-33 115.5 52.7 4.9e-33 114.5 49.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4535 PF15054.6 KEZ43824.1 - 0.28 11.0 5.5 4.1 7.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) MMU163 PF17119.5 KEZ43825.1 - 1.8e-58 197.6 5.2 1.8e-45 155.1 1.3 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Pkinase PF00069.25 KEZ43827.1 - 1.4e-75 254.0 0.0 2.1e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43827.1 - 1.2e-30 106.6 0.0 4.3e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEZ43827.1 - 1.4e-06 27.8 0.1 0.73 9.1 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KEZ43827.1 - 0.032 13.0 1.1 0.051 12.3 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 KEZ43827.1 - 0.047 13.0 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDT PF00800.18 KEZ43827.1 - 0.064 13.1 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Prephenate dehydratase DFRP_C PF16543.5 KEZ43828.1 - 7.9e-26 90.4 7.8 7.9e-26 90.4 7.8 4.4 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KEZ43828.1 - 1.9e-06 28.5 8.5 1.3e-05 25.8 1.4 3.2 1 1 1 2 2 2 1 Torus domain zf-CCCH PF00642.24 KEZ43828.1 - 2.6e-05 24.0 1.1 2.6e-05 24.0 1.1 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KEZ43828.1 - 0.00034 20.6 6.9 0.00034 20.6 6.9 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 KEZ43828.1 - 0.00041 20.1 10.0 0.0021 17.8 2.2 3.4 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KEZ43828.1 - 0.037 14.2 5.6 0.1 12.8 0.3 2.8 3 0 0 3 3 3 0 Zinc-finger containing family zf-C2H2_4 PF13894.6 KEZ43828.1 - 0.09 13.7 0.9 2.9 8.9 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CCCH_2 PF14608.6 KEZ43828.1 - 0.27 11.8 14.0 1.2 9.7 5.6 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger CS PF04969.16 KEZ43829.1 - 6e-08 33.6 0.7 1e-07 32.8 0.7 1.4 1 1 0 1 1 1 1 CS domain CorA PF01544.18 KEZ43830.1 - 0.0094 15.3 2.9 0.01 15.2 1.4 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Snf7 PF03357.21 KEZ43831.1 - 1.7e-21 76.5 5.9 1.7e-21 76.5 5.9 1.6 2 0 0 2 2 2 1 Snf7 TPR_MLP1_2 PF07926.12 KEZ43831.1 - 0.013 15.5 2.6 0.013 15.5 2.6 2.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Hydrolase_like PF13242.6 KEZ43832.1 - 9e-07 28.9 0.1 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like NACHT PF05729.12 KEZ43833.1 - 1.8e-05 24.7 0.2 0.0001 22.3 0.2 2.2 1 1 0 1 1 1 1 NACHT domain SNF2_N PF00176.23 KEZ43834.1 - 1.4e-32 112.8 0.0 2.2e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ43834.1 - 1.9e-13 50.7 0.0 3.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KEZ43834.1 - 0.00025 20.9 4.2 0.00025 20.9 4.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KEZ43834.1 - 0.018 14.9 3.3 0.018 14.9 3.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 KEZ43834.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_2 PF13639.6 KEZ43834.1 - 0.55 10.6 11.8 0.031 14.6 4.5 2.5 2 0 0 2 2 2 0 Ring finger domain TackOD1 PF18551.1 KEZ43834.1 - 0.85 9.3 8.6 7.7 6.1 4.2 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-C3HC4_3 PF13920.6 KEZ43834.1 - 2.1 8.3 12.3 0.092 12.6 4.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 KEZ43834.1 - 4.2 7.6 8.0 0.24 11.6 2.1 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 KEZ43834.1 - 9.3 6.2 10.0 0.21 11.5 2.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.22 KEZ43836.1 - 1.4e-17 63.8 0.0 1.9e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ43836.1 - 6.8e-05 23.1 0.1 0.00031 21.0 0.1 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ43836.1 - 0.062 12.8 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.9 KEZ43836.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KEZ43836.1 - 0.18 12.1 0.0 0.43 10.8 0.0 1.7 1 1 1 2 2 2 0 AAA domain RNA_pol_Rpb4 PF03874.16 KEZ43837.1 - 2.6e-21 76.2 0.1 3.1e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 HTH_32 PF13565.6 KEZ43837.1 - 0.054 14.1 0.2 0.12 13.0 0.1 1.6 2 0 0 2 2 2 0 Homeodomain-like domain Toxin_trans PF07952.12 KEZ43837.1 - 0.12 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Pribosyl_synth PF14572.6 KEZ43838.1 - 1.9e-43 148.7 1.0 3.5e-38 131.5 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KEZ43838.1 - 5e-32 110.3 0.0 1.1e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KEZ43838.1 - 3.5e-15 55.9 0.1 5.6e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KEZ43838.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase UPF0181 PF03701.14 KEZ43838.1 - 0.13 12.0 0.1 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Glyco_hydro_63 PF03200.16 KEZ43839.1 - 1.2e-08 34.2 9.8 2e-07 30.2 0.1 4.2 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain RasGEF PF00617.19 KEZ43840.1 - 4.6e-46 157.2 0.2 8.7e-46 156.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEZ43840.1 - 1.5e-12 47.6 0.3 6.7e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 KEZ43840.1 - 0.0083 15.7 0.0 0.75 9.4 0.0 2.8 2 1 0 2 2 2 1 Ras family DUF815 PF05673.13 KEZ43840.1 - 0.035 13.3 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 KEZ43840.1 - 0.1 13.0 0.0 0.49 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ43840.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-HIT PF04438.16 KEZ43841.1 - 1.4e-09 37.6 10.5 2e-09 37.1 10.5 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KEZ43841.1 - 0.00012 22.1 5.9 0.00018 21.5 5.9 1.3 1 0 0 1 1 1 1 MYND finger zf-ANAPC11 PF12861.7 KEZ43841.1 - 0.18 11.9 2.0 0.28 11.3 2.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4716 PF15837.5 KEZ43841.1 - 0.19 11.8 0.3 0.19 11.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) zf-B_box PF00643.24 KEZ43841.1 - 0.31 11.2 4.0 0.44 10.7 4.0 1.2 1 0 0 1 1 1 0 B-box zinc finger Nfu_N PF08712.11 KEZ43842.1 - 1.5e-27 95.4 0.0 6.5e-27 93.4 0.0 2.1 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KEZ43842.1 - 5e-27 93.9 0.0 9.2e-27 93.0 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain Glyco_hyd_65N_2 PF14498.6 KEZ43843.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain LSM PF01423.22 KEZ43844.1 - 2.1e-14 52.9 0.0 3.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain NUDIX PF00293.28 KEZ43845.1 - 1.2e-17 64.2 1.5 1.4e-17 64.0 1.5 1.1 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 KEZ43846.1 - 1.1e-47 162.0 0.2 1.7e-47 161.4 0.2 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KEZ43846.1 - 3.5e-18 65.8 0.9 7.5e-18 64.7 0.4 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Ribosomal_60s PF00428.19 KEZ43846.1 - 0.0013 19.3 5.7 0.0029 18.2 5.7 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Paf1 PF03985.13 KEZ43846.1 - 2.2 7.2 10.3 3.8 6.4 0.2 2.1 2 0 0 2 2 2 0 Paf1 OSCP PF00213.18 KEZ43847.1 - 3.2e-47 160.8 0.8 4.1e-47 160.5 0.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.17 KEZ43848.1 - 5e-70 234.9 0.0 6.5e-70 234.5 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family GREB1 PF15782.5 KEZ43849.1 - 5.7 3.9 17.1 7.6 3.5 17.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 KEZ43849.1 - 6.7 4.8 34.8 9.9 4.3 34.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M41 PF01434.18 KEZ43850.1 - 3.8e-53 180.2 0.2 6.2e-53 179.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KEZ43850.1 - 1.4e-42 145.2 0.0 5.5e-42 143.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ43850.1 - 1.8e-08 34.0 0.1 4.3e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KEZ43850.1 - 1.9e-06 27.9 0.0 6e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KEZ43850.1 - 8.2e-05 22.0 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KEZ43850.1 - 0.00012 22.5 0.7 0.0014 19.1 0.7 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KEZ43850.1 - 0.00031 20.4 0.8 0.52 9.9 0.2 2.8 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 KEZ43850.1 - 0.00032 20.5 0.0 0.001 18.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ43850.1 - 0.0009 19.5 0.2 0.033 14.4 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ43850.1 - 0.0051 17.0 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEZ43850.1 - 0.012 14.8 0.0 0.052 12.7 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KEZ43850.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEZ43850.1 - 0.025 14.0 0.2 0.05 13.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KEZ43850.1 - 0.029 13.9 0.0 0.18 11.3 0.0 2.3 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KEZ43850.1 - 0.045 13.0 2.1 0.63 9.3 0.4 2.6 1 1 1 2 2 2 0 Zeta toxin MAP65_ASE1 PF03999.12 KEZ43850.1 - 0.05 12.3 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) AAA_14 PF13173.6 KEZ43850.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KEZ43850.1 - 0.086 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KEZ43850.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KEZ43850.1 - 0.11 11.8 0.1 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 KEZ43850.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KEZ43851.1 - 1.1e-19 69.7 30.3 1.1e-05 25.5 0.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ43851.1 - 2.1e-18 65.8 27.1 4.2e-06 27.0 0.5 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ43851.1 - 1.4e-08 34.8 27.2 0.014 16.2 1.2 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ43851.1 - 0.00033 20.9 3.2 0.52 10.7 0.5 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KEZ43851.1 - 0.0078 16.5 9.5 1.1 9.6 6.3 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KEZ43851.1 - 0.021 14.6 1.4 0.021 14.6 1.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KEZ43851.1 - 0.037 14.4 1.0 0.037 14.4 1.0 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KEZ43851.1 - 0.067 13.9 14.1 0.11 13.2 2.3 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger FOXP-CC PF16159.5 KEZ43851.1 - 0.069 13.8 10.1 7.1 7.3 0.3 4.4 2 1 2 4 4 4 0 FOXP coiled-coil domain GDPD PF03009.17 KEZ43852.1 - 4.4e-63 213.4 0.0 2e-62 211.3 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KEZ43852.1 - 1e-27 96.5 0.1 1.5e-17 63.9 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43852.1 - 4.4e-24 84.5 0.2 2.8e-08 34.1 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ43852.1 - 9.1e-17 60.9 0.0 2.6e-07 30.8 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 KEZ43852.1 - 1.3e-16 61.5 30.5 3.4e-10 40.4 0.2 4.6 4 2 1 5 5 5 3 SPX domain Ank_3 PF13606.6 KEZ43852.1 - 6.4e-15 53.8 2.6 0.0018 18.6 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KEZ43852.1 - 4.4e-14 52.2 6.8 0.00033 21.0 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeat Rbsn PF11464.8 KEZ43852.1 - 2 8.2 3.8 0.71 9.7 0.1 2.1 3 0 0 3 3 3 0 Rabenosyn Rab binding domain DUF866 PF05907.13 KEZ43853.1 - 6.7e-48 162.5 3.3 7.1e-43 146.2 0.5 2.9 2 1 1 3 3 3 2 Eukaryotic protein of unknown function (DUF866) Rpr2 PF04032.16 KEZ43853.1 - 2.3e-15 56.6 2.0 2.2e-14 53.5 0.5 2.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.12 KEZ43853.1 - 0.0025 17.3 1.2 15 5.2 0.0 3.4 3 0 0 3 3 3 1 TFIIB zinc-binding HalOD2 PF18547.1 KEZ43853.1 - 0.099 12.6 0.6 3.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Halobacterial output domain 2 DZR PF12773.7 KEZ43853.1 - 0.13 12.3 1.0 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 KEZ43853.1 - 0.15 12.0 5.2 0.77 9.7 0.1 3.2 4 0 0 4 4 4 0 zinc-ribbon domain ADK_lid PF05191.14 KEZ43853.1 - 0.25 11.3 3.5 2.3 8.3 0.1 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid FYVE PF01363.21 KEZ43853.1 - 0.27 11.4 5.1 1.2 9.3 1.4 2.8 2 1 0 2 2 2 0 FYVE zinc finger zinc_ribbon_15 PF17032.5 KEZ43853.1 - 0.44 11.3 5.7 13 6.7 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon family zf-ZPR1 PF03367.13 KEZ43854.1 - 1.1e-109 363.3 0.0 3.7e-56 189.4 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KEZ43854.1 - 0.014 15.4 2.7 0.76 9.8 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 KEZ43854.1 - 7.4 6.6 5.6 19 5.3 0.0 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain SKG6 PF08693.10 KEZ43855.1 - 2 7.9 6.9 0.096 12.1 0.7 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.25 KEZ43856.1 - 1.3e-37 129.6 0.0 1.9e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43856.1 - 6.1e-16 58.5 0.0 8.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ43856.1 - 0.0032 16.8 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEZ43856.1 - 0.0097 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ43856.1 - 0.021 13.6 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KEZ43856.1 - 0.024 14.6 0.1 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cyclin_N PF00134.23 KEZ43857.1 - 0.036 13.8 0.0 0.086 12.6 0.0 1.6 2 0 0 2 2 2 0 Cyclin, N-terminal domain Cyclin PF08613.11 KEZ43857.1 - 0.23 11.8 0.0 0.33 11.3 0.0 1.2 1 0 0 1 1 1 0 Cyclin Ribonuclease_3 PF00636.26 KEZ43859.1 - 7.8e-44 148.6 0.0 9.6e-21 74.4 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KEZ43859.1 - 3.5e-27 95.1 0.0 2.6e-11 43.8 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KEZ43859.1 - 1.4e-19 70.1 0.1 3.3e-18 65.6 0.1 2.5 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KEZ43859.1 - 6.9e-17 61.8 0.4 2.5e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ43859.1 - 2.5e-16 60.2 0.4 6.1e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ43859.1 - 3.8e-09 36.6 0.0 7.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KEZ43859.1 - 0.001 19.4 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 KEZ43859.1 - 0.0027 17.4 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 KEZ43859.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 KEZ43859.1 - 0.021 13.6 0.0 0.038 12.7 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain dsrm PF00035.26 KEZ43859.1 - 0.021 15.5 0.3 13 6.5 0.0 3.3 3 0 0 3 3 3 0 Double-stranded RNA binding motif Flavi_DEAD PF07652.14 KEZ43859.1 - 0.18 11.8 0.0 0.61 10.1 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain Peptidase_C12 PF01088.21 KEZ43861.1 - 4.9e-54 183.3 0.0 5.9e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Synaptobrevin PF00957.21 KEZ43862.1 - 2e-31 107.6 0.2 2.9e-31 107.1 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KEZ43862.1 - 1.2e-28 98.9 0.1 2.3e-28 98.0 0.0 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Sec1 PF00995.23 KEZ43863.1 - 3e-118 396.6 0.0 3.5e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Spc29 PF17082.5 KEZ43864.1 - 0.034 14.0 0.4 0.053 13.4 0.4 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 PRKCSH-like PF12999.7 KEZ43864.1 - 0.18 11.6 1.1 0.28 11.0 1.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF3496 PF12001.8 KEZ43864.1 - 0.37 11.2 4.1 0.66 10.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) DUF4351 PF14261.6 KEZ43865.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DUF2007 PF09413.10 KEZ43865.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein Presenilin PF01080.17 KEZ43866.1 - 3.9 6.1 3.5 7.6 5.2 3.5 1.5 1 0 0 1 1 1 0 Presenilin Npa1 PF11707.8 KEZ43867.1 - 2.4e-89 300.0 0.0 4.3e-89 299.2 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KEZ43867.1 - 5.3e-57 192.7 0.0 2e-56 190.8 0.0 2.0 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 His_Phos_2 PF00328.22 KEZ43869.1 - 2e-62 211.7 0.0 2.3e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Inositol_P PF00459.25 KEZ43871.1 - 4.1e-64 216.7 0.0 4.8e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 KEZ43872.1 - 2.3e-34 118.9 21.3 4.3e-29 101.5 13.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43872.1 - 3.8e-09 35.9 2.1 3.8e-09 35.9 2.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ43872.1 - 0.66 8.8 14.4 0.064 12.1 4.2 2.6 2 0 0 2 2 2 0 MFS_1 like family DNA_topoisoIV PF00521.20 KEZ43874.1 - 3.9e-119 398.3 0.1 1.6e-118 396.3 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KEZ43874.1 - 9.2e-49 165.0 1.8 9.2e-49 165.0 1.8 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KEZ43874.1 - 8.7e-25 87.2 1.7 1.7e-24 86.3 1.7 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KEZ43874.1 - 2.2e-12 47.5 0.0 5.2e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KEZ43874.1 - 1.9e-06 28.0 0.1 9.1e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Toprim domain Reticulon PF02453.17 KEZ43875.1 - 1.5e-34 119.2 4.0 1.9e-34 118.9 4.0 1.1 1 0 0 1 1 1 1 Reticulon FUSC_2 PF13515.6 KEZ43875.1 - 0.61 10.2 8.8 0.22 11.7 1.7 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like RabGAP-TBC PF00566.18 KEZ43876.1 - 2.9e-42 144.8 0.0 7.2e-42 143.5 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TMF_DNA_bd PF12329.8 KEZ43876.1 - 0.0021 18.0 4.9 0.0021 18.0 4.9 3.1 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF4686 PF15742.5 KEZ43876.1 - 0.0045 16.2 4.9 0.0045 16.2 4.9 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4686) DUF1664 PF07889.12 KEZ43876.1 - 2.6 8.1 6.5 0.26 11.3 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 KEZ43876.1 - 7.3 6.6 11.7 0.29 11.2 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF724 PF05266.14 KEZ43876.1 - 7.3 6.4 14.6 0.63 9.8 2.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Cornifin PF02389.15 KEZ43877.1 - 9.6 6.4 14.9 6.6 6.9 4.9 3.4 2 1 0 2 2 2 0 Cornifin (SPRR) family GCV_H PF01597.19 KEZ43878.1 - 1.9e-32 111.7 1.2 2.3e-32 111.5 1.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 KEZ43878.1 - 0.023 14.5 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme SH3_9 PF14604.6 KEZ43878.1 - 0.065 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Variant SH3 domain Ras PF00071.22 KEZ43879.1 - 1.5e-31 109.2 0.1 1.9e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ43879.1 - 4.5e-24 85.0 0.1 8e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ43879.1 - 1.3e-06 28.0 0.1 1.7e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEZ43879.1 - 0.00023 20.6 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KEZ43879.1 - 0.002 17.0 0.3 0.17 10.7 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TPT PF03151.16 KEZ43881.1 - 1.3e-24 87.1 25.1 1.6e-24 86.8 25.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KEZ43881.1 - 0.0018 17.6 25.1 0.0031 16.8 25.1 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEZ43881.1 - 0.051 13.7 43.2 0.36 11.0 11.3 2.8 3 0 0 3 3 3 0 EamA-like transporter family Glyco_transf_17 PF04724.13 KEZ43882.1 - 1.7e-50 172.1 0.4 3.7e-50 170.9 0.4 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 17 Dak1 PF02733.17 KEZ43883.1 - 2.6e-104 348.5 2.3 3.3e-104 348.1 2.3 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KEZ43883.1 - 1.7e-44 151.8 0.0 3e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 KEZ43884.1 - 4.3e-18 64.8 0.1 5.8e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KEZ43884.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein ECH_2 PF16113.5 KEZ43885.1 - 1.3e-128 429.2 0.0 1.7e-128 428.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KEZ43885.1 - 8.6e-28 97.3 0.1 7.1e-25 87.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase GATA PF00320.27 KEZ43886.1 - 0.0017 17.9 5.8 0.073 12.7 0.8 2.7 2 0 0 2 2 2 2 GATA zinc finger Pol_alpha_B_N PF08418.10 KEZ43887.1 - 1.8e-69 234.4 0.0 2.5e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KEZ43887.1 - 9.4e-37 126.4 0.1 1.4e-36 125.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B An_peroxidase PF03098.15 KEZ43891.1 - 5.2e-35 121.0 0.0 2.6e-24 85.7 0.0 3.5 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KEZ43891.1 - 6e-07 28.6 0.0 2.5e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 SAM_decarbox PF01536.16 KEZ43892.1 - 1e-130 435.9 0.0 1.5e-130 435.3 0.0 1.3 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Glyco_hydro_81 PF03639.13 KEZ43892.1 - 0.077 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain Organ_specific PF10950.8 KEZ43892.1 - 0.13 13.0 0.0 1.6 9.5 0.0 2.2 2 0 0 2 2 2 0 Organ specific protein ParA PF10609.9 KEZ43893.1 - 7.7e-89 297.4 0.0 9.8e-89 297.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KEZ43893.1 - 9.7e-12 45.1 0.0 4e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KEZ43893.1 - 2.6e-05 23.6 0.4 0.00038 19.7 0.4 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KEZ43893.1 - 2.8e-05 24.1 0.0 0.00083 19.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KEZ43893.1 - 7e-05 22.2 0.0 0.00093 18.6 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 KEZ43893.1 - 0.00059 19.5 0.1 0.0011 18.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KEZ43893.1 - 0.021 14.3 0.2 0.076 12.5 0.2 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 KEZ43893.1 - 0.035 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MeaB PF03308.16 KEZ43893.1 - 0.041 12.9 0.2 0.065 12.2 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KEZ43893.1 - 0.11 12.4 1.2 0.34 10.8 0.6 1.9 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KEZ43893.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ank_2 PF12796.7 KEZ43894.1 - 7.3e-47 157.9 1.1 4.2e-12 46.5 0.0 5.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43894.1 - 8.7e-32 109.1 4.1 5.1e-09 36.5 0.0 7.7 4 1 4 9 9 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43894.1 - 9.5e-32 105.5 0.0 0.00087 19.6 0.0 9.3 10 0 0 10 10 8 6 Ankyrin repeat Ank_5 PF13857.6 KEZ43894.1 - 1e-29 102.2 7.3 1.7e-06 28.2 0.0 6.1 3 1 4 7 7 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43894.1 - 3.7e-25 87.2 3.3 0.0038 17.6 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat NACHT PF05729.12 KEZ43894.1 - 2.1e-05 24.5 0.1 0.00023 21.1 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ43894.1 - 0.00047 20.4 0.0 0.0017 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KEZ43894.1 - 0.013 14.8 0.7 0.28 10.4 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 KEZ43894.1 - 0.053 13.3 0.1 0.56 10.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4524 PF15025.6 KEZ43894.1 - 0.064 13.0 1.9 0.42 10.4 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4524) Death PF00531.22 KEZ43894.1 - 0.11 12.7 0.8 99 3.2 0.0 4.6 5 0 0 5 5 5 0 Death domain SMP_C2CD2L PF18696.1 KEZ43894.1 - 0.13 12.0 0.0 26 4.6 0.0 3.2 2 1 2 4 4 4 0 Synaptotagmin-like, mitochondrial and lipid-binding domain APH PF01636.23 KEZ43895.1 - 3.4e-16 59.9 0.4 1.1e-12 48.4 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ43895.1 - 1.4e-07 31.4 0.2 2.2e-07 30.7 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KEZ43895.1 - 8.2e-06 25.5 0.8 0.042 13.4 0.4 2.1 1 1 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.14 KEZ43895.1 - 0.00058 19.2 0.0 0.003 16.8 0.0 1.9 2 0 0 2 2 2 1 Fructosamine kinase Pkinase_Tyr PF07714.17 KEZ43895.1 - 0.069 12.4 0.2 0.69 9.1 0.2 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KEZ43895.1 - 0.2 11.0 0.2 16 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.23 KEZ43896.1 - 9.4e-10 38.8 0.1 2.1e-08 34.4 0.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ43896.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NmrA PF05368.13 KEZ43897.1 - 2.7e-13 50.0 0.0 6.1e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KEZ43897.1 - 6.8e-07 29.4 0.0 1.6e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ43897.1 - 0.00077 19.0 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ43897.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 KR domain CobT_C PF11775.8 KEZ43897.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain p450 PF00067.22 KEZ43898.1 - 3.2e-38 131.7 0.0 3.9e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4328 PF14219.6 KEZ43898.1 - 0.097 12.2 0.6 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) CNDH2_N PF06278.11 KEZ43898.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Methyltransf_11 PF08241.12 KEZ43901.1 - 4.1e-17 62.6 0.0 8.3e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ43901.1 - 2.7e-16 59.9 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ43901.1 - 2.4e-15 57.0 0.1 2e-14 54.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ43901.1 - 1.3e-13 51.1 0.0 1.1e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ43901.1 - 1.2e-12 48.4 0.0 6.1e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEZ43901.1 - 1.4e-12 47.5 0.0 9.3e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase ADH_zinc_N PF00107.26 KEZ43901.1 - 5e-06 26.5 0.1 0.0001 22.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 KEZ43901.1 - 5e-05 22.8 0.0 0.00014 21.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KEZ43901.1 - 0.0015 18.1 0.0 0.28 10.7 0.0 2.3 1 1 0 2 2 2 1 Methionine biosynthesis protein MetW TehB PF03848.14 KEZ43901.1 - 0.011 15.2 0.0 0.035 13.5 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 KEZ43901.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEZ43901.1 - 0.028 14.0 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 KEZ43901.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CAF1A PF12253.8 KEZ43902.1 - 8.1e-22 77.2 2.4 8.1e-22 77.2 2.4 3.4 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A DUF737 PF05300.11 KEZ43902.1 - 0.038 14.4 28.9 0.031 14.6 24.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Raftlin PF15250.6 KEZ43902.1 - 8.2 5.1 15.0 16 4.1 15.0 1.4 1 0 0 1 1 1 0 Raftlin WSC PF01822.19 KEZ43903.1 - 1.6e-23 82.6 23.2 6.2e-15 55.1 1.8 3.5 4 0 0 4 4 4 2 WSC domain LysM PF01476.20 KEZ43903.1 - 7.7e-05 22.7 0.0 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 LysM domain W2 PF02020.18 KEZ43904.1 - 0.19 11.9 1.3 0.91 9.7 0.8 2.3 2 1 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Glyco_hydro_18 PF00704.28 KEZ43905.1 - 5.4e-57 193.9 0.0 1.8e-56 192.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Cellulase PF00150.18 KEZ43905.1 - 6e-20 71.8 1.8 1e-19 71.1 1.8 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KEZ43905.1 - 2.9e-08 33.2 0.1 5.1e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KEZ43905.1 - 0.011 15.2 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase Alpha-amylase PF00128.24 KEZ43905.1 - 0.15 11.6 1.5 2.1 7.8 0.3 2.2 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Lipase_GDSL_2 PF13472.6 KEZ43906.1 - 5.1e-21 75.9 0.0 7.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ43906.1 - 9.9e-11 42.0 0.0 1.6e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 KEZ43906.1 - 1.5e-05 24.3 0.0 2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 KEZ43906.1 - 9.2e-05 22.7 0.0 0.00012 22.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_lke PF16255.5 KEZ43906.1 - 0.0056 16.1 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_M18 PF02127.15 KEZ43907.1 - 1.9e-123 412.5 0.0 2.1e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) EXS PF03124.14 KEZ43908.1 - 8.4e-96 321.2 31.2 1.2e-95 320.6 31.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KEZ43908.1 - 5.4e-80 270.2 0.1 5.4e-80 270.2 0.1 2.0 2 0 0 2 2 2 1 SPX domain DUF4603 PF15376.6 KEZ43908.1 - 0.021 12.3 0.2 0.031 11.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Tub_N PF16322.5 KEZ43908.1 - 0.072 13.5 5.3 0.15 12.4 5.3 1.5 1 0 0 1 1 1 0 Tubby N-terminal DUF883 PF05957.13 KEZ43908.1 - 4.8 7.8 8.3 0.18 12.4 1.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) NOA36 PF06524.12 KEZ43908.1 - 5.6 6.2 7.4 9.1 5.5 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 KEZ43908.1 - 5.9 5.8 12.9 10 5.0 12.9 1.3 1 0 0 1 1 1 0 Paf1 Meth_synt_2 PF01717.18 KEZ43909.1 - 9.8e-10 38.2 0.0 0.00037 19.9 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KEZ43909.1 - 0.02 14.4 0.0 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain FMO-like PF00743.19 KEZ43910.1 - 7e-11 41.2 0.0 1.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEZ43910.1 - 1.6e-08 34.1 0.0 1.7e-06 27.4 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEZ43910.1 - 9.7e-07 28.9 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ43910.1 - 5.2e-06 25.9 0.0 2.1e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KEZ43911.1 - 3.6e-44 151.3 0.0 5.1e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KEZ43911.1 - 6.5e-35 120.4 0.0 9.5e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43911.1 - 3e-19 69.5 0.0 5.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43911.1 - 1.8e-06 28.0 0.0 6.1e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KEZ43911.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEZ43911.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KEZ43911.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TENA_THI-4 PF03070.16 KEZ43912.1 - 0.00014 21.8 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family GMC_oxred_C PF05199.13 KEZ43914.1 - 1.1e-07 32.5 0.0 1.2e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Amidohydro_2 PF04909.14 KEZ43915.1 - 2.9e-27 96.2 0.0 3.3e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase PAF-AH_p_II PF03403.13 KEZ43916.1 - 2.4e-37 128.4 0.0 9.5e-32 109.9 0.0 2.7 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 KEZ43916.1 - 3.9e-22 79.2 0.0 9.7e-22 77.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans PF04082.18 KEZ43916.1 - 1.4e-16 60.4 0.0 2.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Say1_Mug180 PF10340.9 KEZ43916.1 - 4.6e-11 42.2 0.0 9.1e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 KEZ43916.1 - 0.0001 21.3 0.0 0.00046 19.2 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KEZ43916.1 - 0.00036 19.9 0.1 0.42 9.8 0.0 3.3 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KEZ43916.1 - 0.0029 16.7 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase BRCT PF00533.26 KEZ43918.1 - 0.004 17.5 0.0 0.017 15.5 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KEZ43918.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Pheromone PF08015.11 KEZ43918.1 - 0.021 15.8 2.5 0.021 15.8 2.5 7.1 4 3 2 6 6 6 0 Fungal mating-type pheromone DUF3496 PF12001.8 KEZ43918.1 - 0.071 13.5 0.6 0.19 12.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) BRCT_3 PF18428.1 KEZ43918.1 - 0.094 12.8 0.0 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain F-box PF00646.33 KEZ43921.1 - 0.00026 20.8 0.3 0.00073 19.3 0.3 1.8 1 0 0 1 1 1 1 F-box domain Jacalin PF01419.17 KEZ43921.1 - 0.053 13.4 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Jacalin-like lectin domain Dynamin_N PF00350.23 KEZ43922.1 - 7.4e-30 104.2 2.1 7.8e-30 104.1 0.4 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KEZ43922.1 - 2.4e-16 59.8 0.1 8.7e-15 54.7 0.0 2.5 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KEZ43922.1 - 3.6e-07 30.3 0.2 1.7e-06 28.1 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ43922.1 - 0.0044 16.6 0.1 1.5 8.3 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.6 KEZ43922.1 - 0.022 15.2 1.5 0.75 10.2 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain Acetyltransf_6 PF13480.7 KEZ43922.1 - 0.024 14.8 2.0 2.9 8.0 0.1 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_21 PF13304.6 KEZ43922.1 - 0.043 13.6 2.0 0.11 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Bgal_small_N PF02929.17 KEZ43922.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta galactosidase small chain AAA_15 PF13175.6 KEZ43922.1 - 0.078 12.7 1.2 0.65 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.16 KEZ43924.1 - 1.3e-09 37.5 39.7 6e-08 32.0 12.4 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43924.1 - 1.5e-07 30.7 15.2 8.2e-06 24.9 5.9 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter DUF3592 PF12158.8 KEZ43924.1 - 0.78 9.8 6.5 0.33 11.0 0.8 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF3592) FMO-like PF00743.19 KEZ43925.1 - 2e-10 39.7 0.0 1.1e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ43925.1 - 9.8e-09 34.9 0.0 1.4e-06 27.9 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ43925.1 - 3.9e-08 33.4 0.5 1.2e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEZ43925.1 - 1.3e-06 27.9 0.0 7.4e-06 25.3 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ43925.1 - 4.2e-05 22.9 0.0 0.00021 20.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ43925.1 - 0.00039 20.1 0.0 0.1 12.1 0.0 2.9 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ43925.1 - 0.00043 20.3 0.0 0.0014 18.6 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding LBR_tudor PF09465.10 KEZ43925.1 - 0.049 13.4 0.3 0.54 10.1 0.5 2.2 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Pyr_redox PF00070.27 KEZ43925.1 - 0.11 13.0 0.0 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ring_hydroxyl_A PF00848.19 KEZ43926.1 - 3.8e-17 63.0 3.0 1e-11 45.3 3.5 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KEZ43926.1 - 4.4e-15 55.4 0.0 7.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ank_2 PF12796.7 KEZ43928.1 - 4.9e-30 104.0 0.1 4.9e-17 62.3 0.0 7.0 5 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43928.1 - 1.4e-18 67.0 0.1 3.5e-09 37.0 0.0 6.9 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43928.1 - 3.5e-18 65.2 3.2 8.4e-05 22.8 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 KEZ43928.1 - 2.1e-17 63.0 0.3 0.00018 21.7 0.0 5.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43928.1 - 2.2e-17 61.3 1.5 5.2e-05 23.3 0.0 8.5 8 0 0 8 8 8 4 Ankyrin repeat Helo_like_N PF17111.5 KEZ43928.1 - 0.00012 21.5 0.2 0.00052 19.4 0.1 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KEZ43928.1 - 0.00013 22.4 0.2 0.0035 17.8 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain SesA PF17107.5 KEZ43928.1 - 0.00059 20.0 1.3 0.0015 18.7 0.3 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA PF00004.29 KEZ43928.1 - 0.02 15.3 0.0 0.085 13.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KEZ43928.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 KEZ43928.1 - 0.032 14.5 0.0 0.24 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain Nitro_FeMo-Co PF02579.17 KEZ43928.1 - 0.19 12.1 0.4 0.6 10.5 0.0 2.0 2 0 0 2 2 1 0 Dinitrogenase iron-molybdenum cofactor ScdA_N PF04405.14 KEZ43928.1 - 0.2 11.3 2.1 0.4 10.4 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) Ank_2 PF12796.7 KEZ43929.1 - 2e-11 44.3 0.5 2.2e-06 28.2 0.0 2.9 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ43929.1 - 1.8e-10 41.2 0.5 0.00013 22.5 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ43929.1 - 4.2e-07 29.8 0.5 1.3 9.8 0.0 5.0 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.6 KEZ43929.1 - 0.0001 22.5 0.1 0.013 15.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KEZ43929.1 - 0.00027 21.3 1.8 3 8.5 0.0 4.3 3 1 0 3 3 3 1 Ankyrin repeat RhgB_N PF09284.10 KEZ43930.1 - 5.4e-80 268.5 0.0 7.8e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KEZ43930.1 - 1.5e-33 116.0 0.0 2.4e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KEZ43930.1 - 1.2e-19 69.9 1.6 1.2e-19 69.9 1.6 2.5 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KEZ43930.1 - 0.05 13.9 0.8 0.13 12.6 0.2 2.0 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Abhydrolase_3 PF07859.13 KEZ43931.1 - 9.1e-17 61.6 0.0 1.5e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Mut7-C PF01927.16 KEZ43931.1 - 0.071 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain Pkinase PF00069.25 KEZ43932.1 - 3.8e-15 56.0 0.0 2.8e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ43932.1 - 5.8e-07 29.1 0.0 1.9e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase GMC_oxred_N PF00732.19 KEZ43933.1 - 1.2e-60 205.4 0.0 2.6e-60 204.3 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ43933.1 - 1.4e-28 100.2 0.0 2.6e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEZ43933.1 - 0.00011 21.4 0.2 0.00029 20.0 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KEZ43933.1 - 0.037 13.3 0.4 0.12 11.6 0.1 2.0 3 0 0 3 3 3 0 Thi4 family NAD_binding_8 PF13450.6 KEZ43933.1 - 0.096 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short_C2 PF13561.6 KEZ43934.1 - 2.4e-32 112.4 0.1 3e-32 112.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43934.1 - 2.7e-24 85.7 0.1 3.4e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ43934.1 - 5e-06 26.5 0.2 7.5e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEZ43934.1 - 0.0026 17.7 0.2 0.004 17.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 KEZ43934.1 - 0.0063 15.3 0.0 0.0079 15.0 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NAD_binding_7 PF13241.6 KEZ43934.1 - 0.018 15.5 0.1 0.03 14.7 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 KEZ43934.1 - 0.034 14.1 0.4 0.1 12.6 0.4 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 KEZ43934.1 - 0.054 13.8 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 KEZ43934.1 - 0.059 12.8 0.1 0.089 12.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 KEZ43934.1 - 0.097 12.7 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.16 KEZ43936.1 - 5.6e-42 143.9 31.1 5.6e-42 143.9 31.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ43936.1 - 0.0012 17.4 4.8 0.0018 16.8 4.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3817 PF12823.7 KEZ43936.1 - 0.34 11.7 5.8 1.1 10.1 2.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) DUF3850 PF12961.7 KEZ43937.1 - 0.078 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Bac_luciferase PF00296.20 KEZ43938.1 - 2.3e-63 214.5 1.6 2.9e-63 214.2 1.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 KEZ43939.1 - 8.4e-18 64.4 30.6 1.3e-17 63.8 30.6 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family adh_short_C2 PF13561.6 KEZ43940.1 - 5.6e-10 39.2 0.0 6.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43940.1 - 2.2e-08 33.8 0.0 5.1e-08 32.6 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 KEZ43940.1 - 0.0028 17.2 0.0 0.0052 16.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KEZ43941.1 - 9.7e-26 90.4 0.5 1.5e-25 89.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43941.1 - 4.7e-17 62.3 0.6 6.1e-17 62.0 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEZ43941.1 - 8.6e-07 28.7 0.3 1.2e-05 24.9 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ43941.1 - 2.3e-05 24.4 0.3 4.5e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.18 KEZ43941.1 - 0.029 14.6 0.1 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.6 KEZ43941.1 - 0.11 12.4 0.7 0.16 11.9 0.7 1.4 1 1 0 1 1 1 0 NAD(P)H-binding FMO-like PF00743.19 KEZ43942.1 - 1.7e-55 188.5 0.0 2.9e-55 187.7 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ43942.1 - 1.7e-18 66.9 0.0 8.6e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ43942.1 - 3.9e-14 52.6 0.2 4e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ43942.1 - 4.8e-09 35.8 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KEZ43942.1 - 3.8e-08 33.5 0.7 1.1e-05 25.4 0.1 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KEZ43942.1 - 0.00038 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KEZ43942.1 - 0.00054 20.4 2.4 0.35 11.3 0.1 3.1 2 2 0 2 2 2 2 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KEZ43942.1 - 0.00071 19.0 0.2 0.46 9.8 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 KEZ43942.1 - 0.00078 18.9 0.1 0.22 10.9 0.1 2.3 2 0 0 2 2 2 1 ThiF family Amino_oxidase PF01593.24 KEZ43942.1 - 0.00086 18.7 0.0 0.018 14.4 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.24 KEZ43942.1 - 0.0017 18.0 4.0 0.13 11.9 0.0 3.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 KEZ43942.1 - 0.0018 18.5 0.2 0.016 15.4 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KEZ43942.1 - 0.0018 17.9 0.5 0.0076 15.8 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Prenylcys_lyase PF07156.14 KEZ43942.1 - 0.0087 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Prenylcysteine lyase Shikimate_DH PF01488.20 KEZ43942.1 - 0.0095 16.0 0.3 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KEZ43942.1 - 0.012 15.2 0.1 0.47 10.0 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HI0933_like PF03486.14 KEZ43942.1 - 0.018 13.7 0.1 4.4 5.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KEZ43942.1 - 0.039 14.5 1.7 5 7.7 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEZ43942.1 - 0.065 13.5 0.7 2.1 8.6 0.1 2.7 3 0 0 3 3 3 0 TrkA-N domain ELFV_dehydrog PF00208.21 KEZ43942.1 - 0.11 12.2 0.3 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.19 KEZ43942.1 - 0.32 10.2 0.8 19 4.4 0.0 2.4 2 1 1 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 KEZ43942.1 - 0.33 10.8 1.5 0.6 10.0 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KEZ43942.1 - 0.45 10.2 2.6 0.64 9.6 0.0 2.3 3 0 0 3 3 2 0 Ketopantoate reductase PanE/ApbA Gpr1_Fun34_YaaH PF01184.19 KEZ43943.1 - 8.2e-28 97.4 17.2 1e-27 97.1 17.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4133 PF13571.6 KEZ43943.1 - 2.6 8.5 9.9 0.11 12.8 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) Abhydrolase_6 PF12697.7 KEZ43944.1 - 5.6e-05 23.9 0.2 7.5e-05 23.4 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAP2 PF01569.21 KEZ43945.1 - 2e-07 30.8 0.9 4.9e-07 29.6 0.1 1.9 2 0 0 2 2 2 1 PAP2 superfamily AA_permease PF00324.21 KEZ43946.1 - 6.4e-104 348.2 35.0 1.1e-103 347.4 35.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ43946.1 - 1.3e-20 73.7 33.6 1.6e-20 73.3 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AhpC-TSA PF00578.21 KEZ43947.1 - 3.4e-36 123.9 0.0 4.4e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KEZ43947.1 - 1.5e-13 50.7 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KEZ43947.1 - 1.1e-12 47.6 0.0 1.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin HNH_2 PF13391.6 KEZ43948.1 - 2.8e-05 24.2 0.1 6.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_45 PF02015.16 KEZ43949.1 - 1.8e-20 73.7 5.0 2.4e-20 73.4 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 p450 PF00067.22 KEZ43950.1 - 1.9e-33 116.0 0.0 2.6e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Malic_M PF03949.15 KEZ43952.1 - 5.3e-94 314.3 0.1 6.9e-94 313.9 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KEZ43952.1 - 8.2e-61 205.0 0.0 1.3e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Endosulfine PF04667.17 KEZ43952.1 - 0.086 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region PTR2 PF00854.21 KEZ43954.1 - 2.4e-81 273.6 7.2 7.5e-81 272.0 6.7 1.8 2 0 0 2 2 2 1 POT family MFS_1 PF07690.16 KEZ43955.1 - 1.4e-20 73.6 57.8 4.4e-19 68.6 35.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KEZ43956.1 - 3.5e-49 167.8 0.0 4.9e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KEZ43956.1 - 0.0052 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 AzlD PF05437.12 KEZ43956.1 - 0.11 12.7 0.3 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) HCV_NS5a PF01506.19 KEZ43956.1 - 0.53 10.2 1.4 0.79 9.7 0.1 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Histidinol_dh PF00815.20 KEZ43957.1 - 1.9e-138 461.9 0.0 2.3e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase adh_short_C2 PF13561.6 KEZ43958.1 - 3.7e-37 128.1 0.7 5.1e-37 127.7 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ43958.1 - 6.8e-37 126.8 0.0 1.1e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ43958.1 - 8.9e-11 42.0 0.3 1.5e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.11 KEZ43959.1 - 2.9e-09 36.5 0.0 5.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KEZ43959.1 - 0.043 13.4 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin AAA_12 PF13087.6 KEZ43961.1 - 2.5e-21 76.2 0.0 4.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ43961.1 - 1.3e-09 38.2 0.0 0.00018 21.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 KEZ43961.1 - 0.00014 21.6 0.0 0.00067 19.4 0.0 2.2 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KEZ43961.1 - 0.00047 19.9 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEZ43961.1 - 0.0007 20.0 0.0 0.0024 18.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KEZ43961.1 - 0.042 13.7 0.1 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Helicase MFS_1 PF07690.16 KEZ43962.1 - 2.7e-35 121.9 30.0 2.7e-35 121.9 30.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43962.1 - 2.1e-14 53.2 9.5 2.1e-14 53.2 9.5 3.2 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ43962.1 - 0.0014 17.2 6.2 0.0025 16.3 6.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrophobin PF01185.18 KEZ43963.1 - 1.6e-05 25.5 10.1 4.4e-05 24.0 10.1 1.7 1 1 1 2 2 2 2 Fungal hydrophobin Glyco_hydro_63 PF03200.16 KEZ43963.1 - 0.047 12.5 0.0 0.05 12.4 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain DUF3328 PF11807.8 KEZ43964.1 - 8.1e-28 97.7 0.6 9e-28 97.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.25 KEZ43965.1 - 4.7e-35 120.8 0.1 5.7e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ43965.1 - 5.7e-24 85.0 0.0 7e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ43965.1 - 0.00012 22.0 0.4 0.0002 21.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ43965.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KEZ43965.1 - 0.08 12.3 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3335 PF11814.8 KEZ43965.1 - 0.16 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Peptidase_S8 PF00082.22 KEZ43966.1 - 2.5e-33 115.6 16.6 5.1e-33 114.6 16.6 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEZ43966.1 - 5.4e-09 36.6 0.0 1.1e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 CCDC158 PF15921.5 KEZ43967.1 - 0.33 8.7 0.0 0.42 8.4 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 SGL PF08450.12 KEZ43968.1 - 0.0013 18.4 0.1 0.0041 16.7 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 KEZ43968.1 - 0.079 12.9 0.2 0.67 10.0 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RCC1_2 PF13540.6 KEZ43968.1 - 0.095 12.5 1.8 9.8 6.1 0.0 3.3 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat TRAP-gamma PF07074.12 KEZ43969.1 - 0.12 11.9 0.2 0.12 11.9 0.2 1.7 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) p450 PF00067.22 KEZ43970.1 - 1.6e-69 234.9 0.0 1.8e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.19 KEZ43971.1 - 3.4e-37 128.4 0.0 4.4e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ43971.1 - 3.6e-32 111.9 0.0 5.6e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ43971.1 - 0.073 12.1 1.9 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Tyrosinase PF00264.20 KEZ43972.1 - 8.6e-30 104.7 0.0 1.6e-29 103.8 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Catalase PF00199.19 KEZ43973.1 - 1.3e-176 587.4 0.0 1.5e-176 587.1 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KEZ43973.1 - 5.4e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive TauD PF02668.16 KEZ43974.1 - 8.6e-37 127.4 0.2 1.2e-36 126.9 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Arginase PF00491.21 KEZ43975.1 - 2.9e-90 302.6 0.0 3.4e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KEZ43975.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.18 KEZ43976.1 - 1e-57 194.3 17.1 2.4e-30 105.3 3.2 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KEZ43976.1 - 1.7e-05 24.9 14.3 1.7e-05 24.9 14.3 3.9 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.16 KEZ43977.1 - 1.9e-44 152.1 43.7 4.9e-38 131.0 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ43977.1 - 5.1e-14 52.0 9.7 5.1e-14 52.0 9.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ43977.1 - 0.00031 19.3 4.8 0.00031 19.3 4.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Lipase_GDSL_2 PF13472.6 KEZ43978.1 - 4e-13 50.1 0.0 1.2e-12 48.7 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CHAT PF12770.7 KEZ43978.1 - 1.4e-08 34.5 0.0 3.5e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 CHAT domain NACHT PF05729.12 KEZ43978.1 - 6.3e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Lipase_GDSL PF00657.22 KEZ43978.1 - 0.00015 21.8 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KEZ43978.1 - 0.00073 19.7 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AAA_16 PF13191.6 KEZ43978.1 - 0.0029 18.0 1.0 0.019 15.3 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 KEZ43978.1 - 0.0088 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Peptidase_C25 PF01364.18 KEZ43978.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C25 AAA_7 PF12775.7 KEZ43978.1 - 0.038 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KEZ43978.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Transferase PF02458.15 KEZ43979.1 - 4.5e-07 28.9 0.0 1.6e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Transferase family GST_N_4 PF17172.4 KEZ43980.1 - 3.4e-18 66.2 0.0 4.4e-15 56.2 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEZ43980.1 - 3.1e-07 30.1 0.0 8.5e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEZ43980.1 - 0.0001 22.3 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.21 KEZ43981.1 - 1.1e-35 123.5 0.0 1.9e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 KEZ43981.1 - 0.25 10.4 1.1 1 8.3 1.1 1.9 1 1 0 1 1 1 0 Phosphate transporter family PBP_like_2 PF12849.7 KEZ43982.1 - 2.3e-10 40.6 2.5 3.4e-10 40.1 2.5 1.2 1 0 0 1 1 1 1 PBP superfamily domain Glyco_hydro_61 PF03443.14 KEZ43983.1 - 3e-56 190.6 0.1 3.4e-56 190.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glycogen_syn PF05693.13 KEZ43984.1 - 2.1e-231 769.9 0.0 2.6e-231 769.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 KEZ43984.1 - 3.5e-06 26.9 0.1 8e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KEZ43984.1 - 9.8e-06 25.2 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ43984.1 - 1.4e-05 25.5 0.0 0.00014 22.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ43984.1 - 0.00017 22.0 0.2 0.00053 20.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ43984.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PHO4 PF01384.20 KEZ43985.1 - 9.5e-113 376.7 14.6 1.1e-112 376.5 14.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Dioxygenase_C PF00775.21 KEZ43986.1 - 5.2e-40 136.8 0.0 7e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KEZ43986.1 - 6.8e-25 86.7 0.2 1.2e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 KEZ43986.1 - 9.7e-05 22.6 0.1 0.00025 21.3 0.1 1.7 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 KEZ43986.1 - 0.011 16.0 0.0 0.039 14.2 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Exo_endo_phos PF03372.23 KEZ43987.1 - 0.00047 19.7 0.1 0.00089 18.8 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Memo PF01875.17 KEZ43987.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Memo-like protein MFS_1 PF07690.16 KEZ43988.1 - 2.1e-18 66.4 8.7 3.2e-13 49.3 4.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ43988.1 - 0.00022 20.6 1.0 0.00022 20.6 1.0 1.5 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 KEZ43988.1 - 0.072 11.7 2.3 0.095 11.3 0.2 1.8 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like Fungal_trans PF04082.18 KEZ43989.1 - 2e-07 30.3 0.1 4.5e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ43989.1 - 0.0004 20.5 10.4 0.00085 19.4 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 KEZ43990.1 - 2.6e-51 174.5 0.0 7.6e-46 156.6 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III Mannosidase_ig PF17786.1 KEZ43991.1 - 2.3e-12 47.3 0.1 7.3e-12 45.7 0.1 1.9 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KEZ43991.1 - 1.1e-06 29.2 0.0 7.7e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KEZ43991.1 - 0.0011 18.9 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_GlcNase PF18368.1 KEZ43991.1 - 0.1 12.8 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain Zn_clus PF00172.18 KEZ43993.1 - 0.00014 22.0 6.6 0.00027 21.0 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEZ43994.1 - 5.2e-78 262.9 16.8 5.9e-78 262.7 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ43994.1 - 6.3e-20 71.4 38.0 1.5e-17 63.6 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.24 KEZ43996.1 - 5.9e-30 104.6 0.1 9.5e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Bac_luciferase PF00296.20 KEZ43997.1 - 5.3e-60 203.5 0.0 7.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase HNH_repeat PF18780.1 KEZ43997.1 - 0.028 14.2 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Homing endonuclease repeat MFS_1 PF07690.16 KEZ43998.1 - 6.4e-31 107.6 25.2 6.5e-31 107.5 24.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 KEZ43999.1 - 3.5e-14 52.1 0.1 3.8e-13 48.7 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ43999.1 - 1.6e-09 37.8 0.0 5.1e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ43999.1 - 2.7e-05 23.6 0.0 0.00013 21.3 0.0 2.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ43999.1 - 7.1e-05 22.2 0.1 0.00032 20.1 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ43999.1 - 0.00012 21.4 0.2 0.0074 15.5 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEZ43999.1 - 0.00047 19.5 0.1 0.0015 17.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KEZ43999.1 - 0.027 14.5 0.3 0.59 10.1 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.16 KEZ44001.1 - 5.5e-35 120.9 29.5 1.5e-34 119.5 28.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MASE2 PF05230.11 KEZ44001.1 - 0.74 9.9 8.2 5.5 7.1 0.3 3.0 2 0 0 2 2 2 0 MASE2 domain Peptidase_S8 PF00082.22 KEZ44002.1 - 3.8e-30 105.2 8.0 6.6e-30 104.4 7.8 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEZ44002.1 - 2.4e-15 56.9 0.0 4.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 ADH_zinc_N PF00107.26 KEZ44003.1 - 4e-17 62.4 0.0 5.5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KEZ44003.1 - 1.3e-16 60.4 0.1 3.1e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KEZ44003.1 - 8e-07 30.2 0.0 1.3e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3938 PF13074.6 KEZ44005.1 - 0.0048 17.1 2.6 0.14 12.4 0.2 2.8 1 1 0 2 2 2 2 Protein of unknown function (DUF3938) NdhL PF10716.9 KEZ44005.1 - 6.7 6.7 8.0 1.4 9.0 0.1 3.2 4 0 0 4 4 4 0 NADH dehydrogenase transmembrane subunit p450 PF00067.22 KEZ44006.1 - 3.3e-30 105.2 0.2 5.8e-18 64.9 1.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 SAM_Exu PF18609.1 KEZ44006.1 - 0.19 11.8 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Exuperantia SAM-like domain GSu_C4xC__C2xCH PF09698.10 KEZ44007.1 - 5.7 7.8 6.9 0.69 10.7 0.9 2.6 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) NAD_binding_10 PF13460.6 KEZ44008.1 - 2.3e-07 30.9 0.0 4.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding DUF2122 PF09895.9 KEZ44008.1 - 0.075 13.4 0.3 0.21 12.0 0.0 1.8 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) Prominin PF05478.11 KEZ44009.1 - 0.026 12.5 0.5 0.056 11.4 0.1 1.7 2 0 0 2 2 2 0 Prominin Peptidase_M43 PF05572.13 KEZ44010.1 - 1.2e-17 64.2 0.2 1.9e-17 63.6 0.2 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KEZ44010.1 - 1.1e-07 32.2 0.3 1.5e-07 31.8 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KEZ44010.1 - 7e-06 26.6 0.0 2.3e-05 24.9 0.0 1.7 1 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KEZ44010.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KEZ44010.1 - 0.0043 16.1 0.3 0.0065 15.5 0.3 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 KEZ44010.1 - 0.062 12.9 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SET PF00856.28 KEZ44011.1 - 2.7e-11 44.1 0.1 9.8e-10 39.1 0.1 2.3 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 KEZ44011.1 - 0.032 14.5 0.2 0.089 13.1 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat LCIB_C_CA PF18599.1 KEZ44012.1 - 0.11 11.8 1.0 0.18 11.1 1.0 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Romo1 PF10247.9 KEZ44012.1 - 0.17 12.2 3.5 7.3 7.0 0.4 2.7 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 DUF1689 PF07954.11 KEZ44012.1 - 0.22 11.9 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Ank_2 PF12796.7 KEZ44013.1 - 2.9e-11 43.8 0.1 4.4e-08 33.6 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ44013.1 - 3.6e-08 33.1 0.7 0.26 11.9 0.0 5.1 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KEZ44013.1 - 1e-06 29.1 0.3 0.0014 19.2 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Stig1 PF04885.13 KEZ44013.1 - 5.7e-06 26.9 4.1 1.3e-05 25.8 4.1 1.5 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 Ank PF00023.30 KEZ44013.1 - 1e-05 25.7 1.4 0.87 10.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KEZ44013.1 - 1.4e-05 25.3 0.9 0.033 14.5 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Syntaxin-6_N PF09177.11 KEZ44013.1 - 0.18 12.4 0.0 0.5 10.9 0.0 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Copper-fist PF00649.18 KEZ44014.1 - 6.6e-13 47.9 3.6 6.6e-13 47.9 3.6 1.6 2 0 0 2 2 2 1 Copper fist DNA binding domain Metallothio_Euk PF12749.7 KEZ44014.1 - 0.75 10.0 9.0 1.2 9.3 9.0 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein Phospholip_A2_3 PF09056.11 KEZ44015.1 - 5.5e-46 155.8 0.2 7e-46 155.4 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Sugar_tr PF00083.24 KEZ44016.1 - 1.2e-88 297.9 17.0 1.4e-88 297.7 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ44016.1 - 8.2e-22 77.6 42.0 9.3e-17 61.0 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ44016.1 - 0.00038 19.0 4.1 0.00038 19.0 4.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SWIRM-assoc_3 PF16498.5 KEZ44016.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal OATP PF03137.20 KEZ44016.1 - 5.4 5.2 11.1 0.98 7.6 0.2 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ADH_N PF08240.12 KEZ44017.1 - 3.4e-29 100.9 3.7 6.6e-29 100.0 3.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ44017.1 - 1.2e-22 80.2 1.2 2.2e-22 79.4 1.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ44017.1 - 1.6e-09 38.9 0.1 3.2e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ44017.1 - 1.2e-05 24.9 2.5 2.9e-05 23.6 2.5 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus NAS PF03059.16 KEZ44017.1 - 0.02 14.3 0.1 0.043 13.2 0.1 1.6 1 1 0 1 1 1 0 Nicotianamine synthase protein TrkA_N PF02254.18 KEZ44017.1 - 0.049 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain MIP PF00230.20 KEZ44018.1 - 8.2e-07 29.0 0.1 1.1e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.16 KEZ44019.1 - 5.7e-18 65.0 21.8 1.7e-17 63.4 21.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily LigB PF02900.18 KEZ44020.1 - 4.2e-29 101.5 0.1 4.8e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3632 PF12311.8 KEZ44021.1 - 7.1e-28 98.2 1.6 1.2e-27 97.5 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) YppF PF14178.6 KEZ44021.1 - 0.034 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 YppF-like protein E1-E2_ATPase PF00122.20 KEZ44022.1 - 2.9e-33 114.9 18.5 1.9e-24 86.2 0.6 4.1 5 0 0 5 5 5 3 E1-E2 ATPase Hydrolase PF00702.26 KEZ44022.1 - 5.3e-17 62.8 0.0 1.4e-16 61.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ44022.1 - 3.1e-11 42.8 0.0 7.3e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ44022.1 - 0.0027 17.5 0.1 0.0057 16.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AphA_like PF14557.6 KEZ44022.1 - 0.037 13.7 0.3 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator Enolase_C PF00113.22 KEZ44023.1 - 5.9e-113 377.0 0.0 7.5e-113 376.7 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KEZ44023.1 - 1.8e-51 173.7 0.1 4.4e-51 172.5 0.0 1.6 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KEZ44023.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like Lipase_GDSL_2 PF13472.6 KEZ44024.1 - 1.7e-15 57.8 0.1 2.7e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ44024.1 - 1.5e-11 44.7 0.0 2.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KEZ44024.1 - 0.00058 20.0 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KEZ44024.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 OSK domain GMC_oxred_N PF00732.19 KEZ44025.1 - 5.3e-60 203.3 0.0 8.6e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ44025.1 - 9.3e-26 91.1 0.0 2e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ44025.1 - 2e-06 27.2 0.7 0.029 13.5 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ44025.1 - 2.7e-05 24.0 0.0 0.00017 21.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ44025.1 - 8.6e-05 21.9 0.2 0.021 14.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ44025.1 - 0.00048 20.3 0.4 0.0011 19.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ44025.1 - 0.001 18.4 0.0 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ44025.1 - 0.0028 18.2 0.2 0.0078 16.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ44025.1 - 0.0083 15.4 0.2 0.017 14.4 0.2 1.5 1 0 0 1 1 1 1 Thi4 family GDI PF00996.18 KEZ44025.1 - 0.014 13.9 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.12 KEZ44025.1 - 0.019 14.0 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KEZ44025.1 - 0.16 10.6 0.1 0.29 9.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein HPP PF04982.13 KEZ44028.1 - 2.7e-35 121.2 7.1 3.3e-35 120.9 7.1 1.1 1 0 0 1 1 1 1 HPP family Ank_4 PF13637.6 KEZ44030.1 - 1.2e-11 44.8 0.0 6.3e-06 26.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ44030.1 - 3.5e-10 40.3 0.0 3.6e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ44030.1 - 3.5e-05 24.0 0.0 0.0014 19.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KEZ44030.1 - 4e-05 23.7 0.0 0.0015 18.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KEZ44030.1 - 0.0028 17.9 0.0 0.074 13.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Baculo_PEP_C PF04513.12 KEZ44031.1 - 0.028 14.5 12.7 0.33 11.0 7.2 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 KEZ44033.1 - 3.3e-28 98.6 24.9 3.3e-28 98.6 24.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1435 PF07256.12 KEZ44033.1 - 0.72 10.0 3.6 9.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) TauD PF02668.16 KEZ44034.1 - 4.2e-51 174.3 0.1 5e-51 174.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Myosin-VI_CBD PF16521.5 KEZ44035.1 - 0.1 12.6 0.0 9.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Myosin VI cargo binding domain DUF5534 PF17686.1 KEZ44036.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) AAA_16 PF13191.6 KEZ44037.1 - 3.6e-08 34.0 0.0 1.5e-07 32.0 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KEZ44037.1 - 1.7e-07 30.7 0.0 4.5e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.6 KEZ44037.1 - 0.00077 19.7 0.8 0.34 11.2 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ44037.1 - 0.035 14.2 8.7 0.18 12.0 1.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KEZ44037.1 - 0.041 13.8 0.3 0.16 11.8 0.0 2.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea TPR_10 PF13374.6 KEZ44037.1 - 0.076 12.9 3.4 15 5.6 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ44037.1 - 0.29 11.0 8.0 1 9.3 1.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C15 PF01470.17 KEZ44039.1 - 0.0038 17.4 0.0 0.042 14.0 0.0 2.0 2 0 0 2 2 2 1 Pyroglutamyl peptidase MepB PF08877.10 KEZ44039.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 MepB protein SNF2_N PF00176.23 KEZ44040.1 - 3.1e-63 213.6 0.1 4.3e-63 213.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ44040.1 - 6.7e-14 52.2 0.0 2.6e-13 50.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ44040.1 - 4.4e-09 36.6 0.1 9.1e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ44040.1 - 1.3e-06 28.3 0.1 4.1e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KEZ44040.1 - 0.002 17.4 0.1 0.0039 16.4 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_UBOX PF13445.6 KEZ44040.1 - 0.0043 17.0 2.4 0.012 15.6 2.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEZ44040.1 - 0.0077 16.1 1.0 0.026 14.4 1.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KEZ44040.1 - 0.019 13.9 0.5 0.16 10.8 0.5 2.1 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-RING_5 PF14634.6 KEZ44040.1 - 0.023 14.6 9.3 0.052 13.5 9.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 KEZ44040.1 - 0.03 14.1 3.7 0.091 12.6 3.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KEZ44040.1 - 0.091 12.6 8.3 0.2 11.5 8.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEZ44040.1 - 0.095 12.6 6.4 0.29 11.0 6.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEZ44040.1 - 0.39 11.1 8.5 1.2 9.6 8.5 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 KEZ44040.1 - 0.77 9.7 15.4 0.14 12.0 10.5 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 KEZ44040.1 - 3.8 7.5 6.0 8.6 6.3 6.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.12 KEZ44041.1 - 1.3e-11 44.8 0.0 3.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ44041.1 - 7.4e-07 29.7 0.0 8.1e-06 26.3 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KEZ44041.1 - 1.5e-06 27.6 0.0 7.6e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain zf-C2H2 PF00096.26 KEZ44041.1 - 1.8e-06 28.1 36.5 0.0095 16.3 8.1 5.8 6 0 0 6 6 6 3 Zinc finger, C2H2 type AAA_22 PF13401.6 KEZ44041.1 - 8e-06 26.2 0.1 9.4e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEZ44041.1 - 0.00034 21.0 0.0 0.003 18.0 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KEZ44041.1 - 0.0021 18.0 0.1 0.0056 16.6 0.1 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea zf-met PF12874.7 KEZ44041.1 - 0.003 17.9 18.6 0.02 15.3 5.3 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 KEZ44041.1 - 0.011 16.1 0.2 0.011 16.1 0.2 5.5 8 0 0 8 8 5 0 Zinc-finger double domain ATPase PF06745.13 KEZ44041.1 - 0.017 14.5 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 KEZ44041.1 - 0.024 14.7 0.1 0.66 10.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KEZ44041.1 - 0.075 13.4 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Goodbye PF17109.5 KEZ44041.1 - 0.089 13.2 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain zf-C2H2_4 PF13894.6 KEZ44041.1 - 0.15 13.0 38.9 0.27 12.2 1.2 7.1 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ44041.1 - 0.25 11.7 23.1 0.28 11.5 4.6 4.7 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding Endonuclease_7 PF02945.15 KEZ44041.1 - 0.54 10.2 4.7 1.5 8.8 4.7 1.7 1 0 0 1 1 1 0 Recombination endonuclease VII Aminotran_3 PF00202.21 KEZ44042.1 - 1.6e-15 56.7 0.0 8.4e-09 34.6 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III adh_short_C2 PF13561.6 KEZ44043.1 - 1.5e-57 194.8 3.4 1.7e-57 194.6 3.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ44043.1 - 1.6e-48 164.8 1.3 2.1e-48 164.4 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ44043.1 - 5.3e-12 46.0 0.1 7.8e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ44043.1 - 0.0019 17.7 0.4 0.01 15.3 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.6 KEZ44043.1 - 0.041 14.9 0.1 0.12 13.4 0.1 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.21 KEZ44043.1 - 0.078 13.0 1.5 0.11 12.5 0.3 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Cytochrome_CBB3 PF13442.6 KEZ44043.1 - 0.12 12.7 0.1 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Zn_clus PF00172.18 KEZ44044.1 - 0.12 12.5 4.8 0.28 11.3 4.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_4 PF08386.10 KEZ44045.1 - 4.4e-19 68.5 0.0 1.1e-18 67.2 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 KEZ44045.1 - 3.4e-09 36.7 0.1 5.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold zf-ANAPC11 PF12861.7 KEZ44045.1 - 0.1 12.6 0.6 0.29 11.2 0.0 2.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger HCO3_cotransp PF00955.21 KEZ44046.1 - 4.2e-69 233.7 9.8 5.2e-36 124.5 2.9 2.1 2 0 0 2 2 2 2 HCO3- transporter family DctQ PF04290.12 KEZ44046.1 - 0.36 10.7 10.9 0.63 10.0 0.3 3.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component K_oxygenase PF13434.6 KEZ44047.1 - 2.2e-13 50.1 0.0 1.1e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ44047.1 - 4.4e-07 29.4 0.0 0.022 14.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ44047.1 - 7.2e-07 28.8 0.2 0.04 13.2 0.3 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ44047.1 - 0.0028 17.7 0.4 0.23 11.5 0.2 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KEZ44047.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 KEZ44047.1 - 0.01 14.6 0.0 0.36 9.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KEZ44047.1 - 0.012 14.9 1.0 0.12 11.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KEZ44047.1 - 0.027 14.7 0.9 0.13 12.5 0.0 2.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ44047.1 - 0.034 13.4 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KEZ44047.1 - 0.21 11.1 5.6 9.9 5.6 5.0 3.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase Methyltransf_23 PF13489.6 KEZ44048.1 - 3.2e-26 92.1 0.0 4.3e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44048.1 - 2.2e-10 41.1 0.0 4.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44048.1 - 1.4e-08 34.7 0.0 1.8e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44048.1 - 2.2e-07 31.4 0.0 4.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44048.1 - 1.5e-05 25.6 0.0 6.6e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ44048.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 KEZ44048.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KEZ44048.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TrmB PF01978.19 KEZ44048.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MTS PF05175.14 KEZ44048.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 KEZ44049.1 - 2.4e-56 191.4 0.0 3.2e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_61 PF03443.14 KEZ44050.1 - 1.4e-42 146.0 0.0 1.5e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5324 PF17258.2 KEZ44050.1 - 0.24 11.1 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5324) Lustrin_cystein PF14625.6 KEZ44051.1 - 3.8 8.0 11.9 17 5.9 8.8 2.2 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain Methyltransf_23 PF13489.6 KEZ44052.1 - 3.6e-18 65.9 0.0 5.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44052.1 - 2e-10 41.3 0.0 9.2e-10 39.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44052.1 - 1.5e-08 34.6 0.0 0.00068 19.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44052.1 - 1.9e-08 35.0 0.0 8.7e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44052.1 - 6.2e-08 33.2 0.0 2.1e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KEZ44052.1 - 6.4e-05 23.1 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KEZ44052.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KEZ44052.1 - 0.021 14.2 0.0 1.8 7.8 0.0 2.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ44052.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ44052.1 - 0.057 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KEZ44052.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KEZ44052.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FAM76 PF16046.5 KEZ44053.1 - 0.018 14.4 5.7 0.034 13.5 5.7 1.3 1 0 0 1 1 1 0 FAM76 protein DUF874 PF05917.11 KEZ44053.1 - 0.04 13.0 7.2 0.059 12.4 7.2 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) ARGLU PF15346.6 KEZ44053.1 - 0.48 10.3 31.0 0.86 9.5 31.0 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 LysM PF01476.20 KEZ44055.1 - 8e-12 45.0 0.8 4.9e-07 29.7 0.5 2.5 2 0 0 2 2 2 2 LysM domain Mucin PF01456.17 KEZ44055.1 - 0.12 12.3 21.4 0.016 15.2 12.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein HTH_23 PF13384.6 KEZ44055.1 - 0.13 12.0 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain DUF2845 PF11006.8 KEZ44055.1 - 0.23 11.6 1.9 0.42 10.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) adh_short PF00106.25 KEZ44056.1 - 4.5e-22 78.5 0.0 5.7e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ44056.1 - 8e-17 61.6 0.0 1e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KEZ44056.1 - 3.3e-09 36.6 0.0 7.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KEZ44056.1 - 1.7e-08 34.2 0.0 0.00046 19.7 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase KR PF08659.10 KEZ44056.1 - 1.5e-07 31.6 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KEZ44056.1 - 8.1e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KEZ44056.1 - 0.00026 20.6 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KEZ44056.1 - 0.0021 17.3 0.1 0.018 14.3 0.0 2.2 2 1 1 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.15 KEZ44056.1 - 0.078 12.1 0.1 0.36 9.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 KEZ44057.1 - 1.9e-06 27.1 37.6 2.1e-06 26.9 36.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEZ44057.1 - 4.8e-05 23.1 1.6 0.00014 21.6 1.6 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MtN3_slv PF03083.16 KEZ44057.1 - 0.073 13.1 0.0 0.33 11.0 0.0 2.1 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange NPP1 PF05630.11 KEZ44059.1 - 1.9e-62 210.9 0.4 3.3e-62 210.1 0.4 1.4 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) VCBS PF13517.6 KEZ44059.1 - 2.6e-35 120.8 75.6 3e-09 37.3 7.6 8.6 4 2 5 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HeLo PF14479.6 KEZ44059.1 - 1.8e-20 73.7 0.0 2.8e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Lipase_GDSL_2 PF13472.6 KEZ44059.1 - 9.6e-18 65.2 1.0 5.2e-17 62.8 0.9 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ44059.1 - 3.7e-06 27.0 0.0 9.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KEZ44059.1 - 4.3e-05 22.9 26.0 0.64 9.4 0.1 8.6 4 3 2 8 8 8 2 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.6 KEZ44059.1 - 0.00029 21.0 0.0 0.00056 20.1 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Itfg2 PF15907.5 KEZ44059.1 - 1.4 7.8 5.3 52 2.7 0.0 4.2 5 0 0 5 5 5 0 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 KEZ44059.1 - 4.3 7.6 66.5 4.8 7.4 1.8 10.0 9 0 0 9 9 9 0 FG-GAP repeat GW PF13457.6 KEZ44059.1 - 5.6 7.7 6.0 10 6.8 0.3 4.0 4 1 0 4 4 4 0 GW (Gly-Tryp) dipeptide domain Fungal_trans_2 PF11951.8 KEZ44060.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cyclase PF04199.13 KEZ44060.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative cyclase DUF3176 PF11374.8 KEZ44061.1 - 1.2e-27 96.2 0.9 1.2e-27 96.2 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) ApbA_C PF08546.11 KEZ44062.1 - 4.8e-32 110.8 0.0 7.3e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KEZ44062.1 - 1.7e-28 99.2 0.0 2.4e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HutD PF05962.11 KEZ44062.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 HutD GerPB PF10803.8 KEZ44063.1 - 0.041 14.0 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Spore germination GerPB SYS1 PF09801.9 KEZ44065.1 - 5e-48 162.9 0.9 5.8e-48 162.7 0.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Aspzincin_M35 PF14521.6 KEZ44067.1 - 5.3e-05 23.8 0.0 0.00025 21.6 0.0 2.0 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase PSII PF00421.19 KEZ44067.1 - 0.05 12.3 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein PIP5K PF01504.18 KEZ44069.1 - 7.5e-103 343.5 0.2 1.3e-102 342.7 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Acyl-CoA_dh_N PF02771.16 KEZ44070.1 - 1.7e-24 86.7 0.5 4.8e-24 85.2 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KEZ44070.1 - 1.2e-22 80.8 0.8 2.2e-22 79.9 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ44070.1 - 1.4e-15 57.3 0.0 3.1e-15 56.2 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KEZ44070.1 - 2.9e-06 27.6 1.0 7.2e-06 26.3 1.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 KEZ44071.1 - 1.6e-52 176.8 0.0 1.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ44071.1 - 0.0048 16.6 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KEZ44071.1 - 0.037 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KEZ44071.1 - 0.046 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.12 KEZ44072.1 - 6.1e-32 110.9 0.0 1.1e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEZ44072.1 - 1.4e-20 73.4 0.2 5.5e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KEZ44072.1 - 3e-18 66.1 17.2 9.7e-18 64.5 9.7 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KEZ44072.1 - 0.15 12.7 0.0 0.55 10.9 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Lactamase_B_6 PF16661.5 KEZ44074.1 - 3.6e-57 192.9 0.0 5.4e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KEZ44074.1 - 9.4e-48 162.6 0.6 9.4e-48 162.6 0.6 1.6 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KEZ44074.1 - 2.2e-15 56.9 0.0 6.9e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KEZ44074.1 - 8.9e-15 54.4 0.0 2.2e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain YbbR PF07949.12 KEZ44074.1 - 0.041 14.2 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 YbbR-like protein Tim54 PF11711.8 KEZ44074.1 - 0.18 10.6 2.2 0.32 9.7 2.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec23_trunk PF04811.15 KEZ44075.1 - 1.1e-52 179.1 0.0 6.1e-52 176.6 0.0 2.1 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KEZ44075.1 - 1.7e-22 79.1 0.1 3.7e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KEZ44075.1 - 1.5e-17 64.1 0.0 2.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KEZ44075.1 - 7e-15 54.8 6.7 1.4e-14 53.8 6.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KEZ44075.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-FPG_IleRS PF06827.14 KEZ44075.1 - 7.7 6.5 6.6 4.1 7.3 3.4 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS tRNA-synt_2 PF00152.20 KEZ44076.1 - 1.4e-74 251.0 0.0 2.8e-74 250.0 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KEZ44076.1 - 0.062 12.8 0.1 4.3 6.7 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) CorA PF01544.18 KEZ44077.1 - 0.00031 20.2 0.3 0.00031 20.2 0.3 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein HET PF06985.11 KEZ44078.1 - 9.7e-07 29.2 4.4 0.00017 22.0 4.4 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) XPG_N PF00752.17 KEZ44079.1 - 1.9e-32 111.7 0.0 1.9e-32 111.7 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 KEZ44079.1 - 2.5e-31 107.9 1.8 3.1e-31 107.6 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 KEZ44079.1 - 5e-06 27.0 0.4 4.5e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KEZ44079.1 - 0.02 15.5 0.0 0.055 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.7 KEZ44079.1 - 0.082 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Acyl-CoA_dh_1 PF00441.24 KEZ44080.1 - 6.7e-42 143.2 0.3 9.4e-42 142.8 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ44080.1 - 1.9e-20 72.8 0.1 3.4e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KEZ44080.1 - 2.2e-19 69.3 0.1 4.2e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 KEZ44080.1 - 4.6e-19 69.1 0.0 1e-18 68.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KEZ44080.1 - 1.3e-08 35.2 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEC-1_N PF04625.13 KEZ44080.1 - 0.46 9.5 7.3 0.79 8.7 7.3 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.19 KEZ44080.1 - 2.5 8.8 12.3 5.1 7.8 12.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein CAP_N PF01213.19 KEZ44080.1 - 3.1 7.2 7.5 4.6 6.6 7.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Actino_peptide PF14408.6 KEZ44081.1 - 1.5 9.0 9.8 2.3 8.4 2.2 2.8 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes Fungal_trans_2 PF11951.8 KEZ44082.1 - 2.1e-28 99.2 1.4 1.5e-17 63.5 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ44082.1 - 1.5e-08 34.6 12.2 2.8e-08 33.8 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KEZ44082.1 - 0.074 13.0 4.7 0.25 11.4 4.7 2.0 1 0 0 1 1 1 0 AT hook motif PDE6_gamma PF04868.12 KEZ44083.1 - 0.0074 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Retinal cGMP phosphodiesterase, gamma subunit ABC_tran PF00005.27 KEZ44085.1 - 4e-53 179.6 0.0 3.3e-26 92.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KEZ44085.1 - 5.8e-35 120.6 31.5 2.2e-20 73.0 8.9 3.8 3 1 1 4 4 4 3 ABC-2 type transporter AAA_21 PF13304.6 KEZ44085.1 - 2.6e-13 50.5 5.3 0.041 13.7 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEZ44085.1 - 1.3e-09 38.2 1.2 0.0003 20.7 0.2 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KEZ44085.1 - 1.5e-08 35.0 1.4 0.018 15.3 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KEZ44085.1 - 2.1e-08 33.8 1.8 0.0052 16.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ44085.1 - 2.5e-08 34.5 1.8 0.0091 16.4 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain SMC_N PF02463.19 KEZ44085.1 - 5.8e-08 32.4 3.4 0.0023 17.4 0.1 4.3 4 1 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KEZ44085.1 - 1.9e-06 28.2 4.6 0.0015 18.8 0.1 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KEZ44085.1 - 2.8e-06 27.3 0.0 0.032 14.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 KEZ44085.1 - 1.3e-05 25.1 4.1 0.019 14.7 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KEZ44085.1 - 1.7e-05 25.4 11.6 0.00079 20.0 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 KEZ44085.1 - 0.00012 21.7 1.0 0.34 10.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KEZ44085.1 - 0.00012 22.6 0.1 1.1 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KEZ44085.1 - 0.00013 21.6 1.6 0.37 10.3 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KEZ44085.1 - 0.00016 22.1 0.7 0.086 13.2 0.2 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KEZ44085.1 - 0.00052 20.1 0.9 0.49 10.5 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KEZ44085.1 - 0.00058 19.0 1.9 0.61 9.1 0.2 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.22 KEZ44085.1 - 0.00076 19.8 0.1 1.8 9.0 0.0 2.8 3 0 0 3 3 2 1 RNA helicase ATPase_2 PF01637.18 KEZ44085.1 - 0.0008 19.4 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KEZ44085.1 - 0.001 18.9 0.2 1.3 8.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 KEZ44085.1 - 0.0011 19.4 0.1 0.085 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ44085.1 - 0.0025 18.0 0.2 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KEZ44085.1 - 0.0033 17.3 0.2 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 KEZ44085.1 - 0.0034 17.6 1.2 3.1 8.1 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 KEZ44085.1 - 0.0036 16.7 5.1 0.46 9.8 0.5 3.1 2 1 1 3 3 3 1 FtsK/SpoIIIE family AAA_5 PF07728.14 KEZ44085.1 - 0.0037 17.3 0.7 4.7 7.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KEZ44085.1 - 0.0055 17.1 0.4 8.8 6.8 0.1 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 KEZ44085.1 - 0.011 16.0 0.2 4 7.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 KEZ44085.1 - 0.012 15.5 0.4 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 KEZ44085.1 - 0.018 14.3 0.1 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 KEZ44085.1 - 0.03 14.0 9.2 5 6.7 0.1 3.6 4 0 0 4 4 3 0 AAA ATPase domain PhoH PF02562.16 KEZ44085.1 - 0.031 13.7 0.5 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KEZ44085.1 - 0.035 13.8 0.6 3.4 7.4 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein Pox_A32 PF04665.12 KEZ44085.1 - 0.039 13.4 3.0 0.36 10.3 0.1 2.5 3 0 0 3 3 2 0 Poxvirus A32 protein KAP_NTPase PF07693.14 KEZ44085.1 - 0.039 13.2 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Cytidylate_kin PF02224.18 KEZ44085.1 - 0.045 13.5 0.4 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase DnaB_C PF03796.15 KEZ44085.1 - 0.05 12.9 0.3 1.7 7.9 0.1 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 KEZ44085.1 - 0.066 12.8 0.5 6.8 6.3 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KEZ44085.1 - 0.071 12.8 0.3 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KEZ44085.1 - 0.074 12.6 0.3 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KEZ44085.1 - 0.075 12.9 0.4 9 6.2 0.1 3.7 5 0 0 5 5 4 0 NTPase SRPRB PF09439.10 KEZ44085.1 - 0.076 12.4 0.6 9.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.9 KEZ44085.1 - 0.077 12.2 0.2 11 5.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 KEZ44085.1 - 0.077 12.7 2.3 1.4 8.6 0.1 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 KEZ44085.1 - 0.081 12.6 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 KEZ44085.1 - 0.088 11.6 0.9 1.5 7.6 0.2 2.4 3 0 0 3 3 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 KEZ44085.1 - 0.1 11.9 0.6 5.9 6.1 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 KEZ44085.1 - 0.13 12.1 1.8 7.3 6.4 0.0 3.1 3 0 0 3 3 3 0 Deoxynucleoside kinase TsaE PF02367.17 KEZ44085.1 - 0.13 12.3 0.4 8.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vfa1 PF08432.10 KEZ44085.1 - 0.14 12.5 9.5 0.024 15.0 3.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mg_chelatase PF01078.21 KEZ44085.1 - 0.16 11.3 1.0 23 4.3 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 KEZ44085.1 - 0.8 9.7 5.1 5 7.2 0.0 3.0 3 0 0 3 3 2 0 Dynamin family AAA_11 PF13086.6 KEZ44085.1 - 8.8 6.0 10.4 3.4 7.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain polyprenyl_synt PF00348.17 KEZ44086.1 - 8.2e-71 238.1 0.0 1.7e-70 237.0 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Vma12 PF11712.8 KEZ44087.1 - 1.2e-45 155.0 0.0 2e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 KEZ44087.1 - 0.00096 19.5 0.1 0.0016 18.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SCIMP PF15050.6 KEZ44087.1 - 0.34 11.4 4.3 14 6.1 0.2 2.8 2 1 0 2 2 2 0 SCIMP protein GMC_oxred_N PF00732.19 KEZ44088.1 - 3e-42 145.0 0.0 8.6e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ44088.1 - 3.7e-21 76.2 0.0 2.3e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ44088.1 - 1e-05 24.9 0.0 0.0002 20.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ44088.1 - 0.0017 18.5 0.3 0.0045 17.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ44088.1 - 0.0019 17.5 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KEZ44088.1 - 0.0075 15.4 0.0 0.015 14.3 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEZ44088.1 - 0.009 15.3 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ44088.1 - 0.02 14.5 0.9 0.15 11.6 0.6 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KEZ44088.1 - 0.08 13.2 0.2 0.32 11.3 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 KEZ44088.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Zip PF02535.22 KEZ44089.1 - 4.6e-30 105.0 49.9 1.9e-13 50.3 2.9 3.9 3 1 2 5 5 5 3 ZIP Zinc transporter CLP1_P PF16575.5 KEZ44090.1 - 8.1e-31 107.3 0.0 5.9e-30 104.5 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 KEZ44090.1 - 0.0079 16.5 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ44090.1 - 0.035 14.7 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ44090.1 - 0.038 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KEZ44090.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 KEZ44090.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KEZ44090.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 KEZ44090.1 - 0.1 13.0 0.1 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 KEZ44090.1 - 0.1 12.7 0.0 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 KEZ44090.1 - 0.1 12.8 1.0 0.2 11.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain RNA_polI_A34 PF08208.11 KEZ44091.1 - 8.6e-05 22.7 17.3 8.6e-05 22.7 17.3 5.2 3 1 2 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 PAP2_3 PF14378.6 KEZ44092.1 - 5.5e-25 88.2 9.7 1.1e-24 87.2 9.7 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KEZ44092.1 - 9.2e-12 44.9 4.8 9.2e-12 44.9 4.8 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KEZ44092.1 - 1.3 9.6 7.1 1.9 9.1 1.3 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RseC_MucC PF04246.12 KEZ44092.1 - 5.5 7.0 6.5 0.87 9.5 0.2 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Pkinase PF00069.25 KEZ44093.1 - 4.2e-71 239.4 0.0 5.8e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44093.1 - 1.9e-29 102.7 0.0 2.6e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KEZ44093.1 - 1e-17 64.5 0.1 1.5e-07 31.9 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ44093.1 - 2.1e-15 56.9 1.7 1.5e-06 28.6 0.0 4.2 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ44093.1 - 1.1e-14 54.2 2.4 8.7e-07 29.1 0.2 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ44093.1 - 6.3e-12 44.6 0.2 0.00075 19.8 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KEZ44093.1 - 3.5e-11 43.0 5.5 3.9e-06 27.1 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat Kinase-like PF14531.6 KEZ44093.1 - 5e-06 26.0 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KEZ44093.1 - 0.00021 20.2 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KEZ44093.1 - 0.00028 20.9 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KEZ44093.1 - 0.00029 20.2 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 KEZ44094.1 - 3.9e-11 42.6 0.0 6.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ44094.1 - 5.2e-09 35.8 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.23 KEZ44095.1 - 2.2e-07 31.1 0.1 2.6e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.28 KEZ44096.1 - 1.3e-69 235.3 0.6 1.9e-69 234.8 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEZ44096.1 - 6.8e-14 52.1 50.7 2.9e-12 46.8 20.9 4.5 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.20 KEZ44097.1 - 1.4e-24 85.9 0.0 2.5e-05 24.2 0.1 7.2 7 0 0 7 7 7 4 LysM domain UPF0203 PF05254.12 KEZ44097.1 - 0.012 15.9 0.9 33 4.8 0.0 3.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) Ferric_reduct PF01794.19 KEZ44099.1 - 6.2e-16 58.7 20.2 1.6e-15 57.3 20.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEZ44099.1 - 7.3e-16 58.7 0.0 1.1e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KEZ44099.1 - 0.00013 22.0 0.0 0.0013 18.8 0.0 2.5 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KEZ44099.1 - 0.00021 21.9 0.0 0.022 15.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain VanZ PF04892.12 KEZ44100.1 - 8.6e-10 39.4 2.5 1.3e-09 38.8 2.5 1.2 1 0 0 1 1 1 1 VanZ like family Saf_2TM PF18303.1 KEZ44100.1 - 0.055 13.1 0.5 0.72 9.4 0.0 2.2 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Phage_holin_2_4 PF16082.5 KEZ44100.1 - 0.26 11.0 0.1 0.26 11.0 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Asp-Al_Ex PF06826.12 KEZ44100.1 - 0.31 10.8 3.8 1.1 9.0 3.8 1.8 1 1 0 1 1 1 0 Predicted Permease Membrane Region Bromodomain PF00439.25 KEZ44101.1 - 1.6e-18 66.6 0.4 4.5e-18 65.1 0.4 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KEZ44101.1 - 1.8e-08 34.2 0.0 4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated CbiG_C PF01890.16 KEZ44101.1 - 0.28 11.7 2.0 9.2 6.9 0.4 3.2 3 0 0 3 3 3 0 Cobalamin synthesis G C-terminus PBP1_TM PF14812.6 KEZ44101.1 - 0.3 11.5 16.6 0.11 12.9 5.3 3.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp PF00026.23 KEZ44102.1 - 1.6e-110 369.4 0.0 1.9e-110 369.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ44102.1 - 2e-16 60.7 0.3 6.1e-15 55.9 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KEZ44102.1 - 0.00034 21.1 0.0 0.49 11.0 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KEZ44102.1 - 0.00035 21.2 0.1 3.3 8.4 0.0 3.3 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 KEZ44102.1 - 0.00043 20.1 0.0 0.0069 16.2 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TERB2 PF15101.6 KEZ44103.1 - 2.8 7.9 7.9 7.4 6.6 7.9 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Drc1-Sld2 PF11719.8 KEZ44105.1 - 2.5e-79 268.0 20.9 3.7e-79 267.4 20.9 1.3 1 0 0 1 1 1 1 DNA replication and checkpoint protein Swi5 PF07061.11 KEZ44105.1 - 0.046 13.8 2.7 0.7 10.0 0.0 2.8 2 0 0 2 2 2 0 Swi5 DASH_Spc34 PF08657.10 KEZ44106.1 - 1.6e-49 169.0 1.0 9.5e-24 84.6 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DASH_Spc19 PF08287.11 KEZ44106.1 - 0.0059 16.5 5.5 0.009 15.9 5.5 1.3 1 0 0 1 1 1 1 Spc19 CAP_N PF01213.19 KEZ44106.1 - 0.096 12.2 1.0 0.16 11.5 1.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal OmpH PF03938.14 KEZ44106.1 - 0.54 10.6 3.2 0.82 10.0 3.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase_Tyr PF07714.17 KEZ44107.1 - 4.8e-11 42.4 0.0 8.8e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KEZ44107.1 - 9.2e-11 41.6 0.0 4.7e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KEZ44107.1 - 0.098 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TFIID_20kDa PF03847.13 KEZ44108.1 - 5.5e-19 68.4 0.1 9.7e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A V_ATPase_I PF01496.19 KEZ44108.1 - 0.0058 14.6 1.6 0.0094 13.9 1.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HSM3_C PF18794.1 KEZ44108.1 - 0.11 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, C terminal domain SMAP PF15477.6 KEZ44108.1 - 0.57 11.2 0.1 0.57 11.2 0.1 3.3 3 0 0 3 3 3 0 Small acidic protein family TraG_N PF07916.11 KEZ44108.1 - 1.1 8.1 11.7 3.5 6.4 11.7 1.9 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Peroxin-13_N PF04088.13 KEZ44108.1 - 2.1 8.6 5.6 11 6.3 0.2 2.6 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Rpn3_C PF08375.11 KEZ44110.1 - 2.3e-26 92.0 1.3 8e-26 90.3 1.3 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KEZ44110.1 - 5.7e-22 78.2 0.2 3.7e-21 75.6 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KEZ44110.1 - 0.035 14.2 0.1 0.12 12.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat MOZ_SAS PF01853.18 KEZ44111.1 - 9.2e-54 181.8 0.0 1.6e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KEZ44111.1 - 1.5e-08 34.1 2.1 0.0045 16.6 1.1 2.4 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_1 PF00583.25 KEZ44111.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ44111.1 - 0.036 14.5 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATP-synt_C PF00137.21 KEZ44112.1 - 6.5e-11 42.4 13.0 6.5e-11 42.4 13.0 1.7 2 0 0 2 2 2 1 ATP synthase subunit C RINT1_TIP1 PF04437.13 KEZ44114.1 - 9.9e-174 578.9 0.0 2e-173 577.9 0.0 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF4164 PF13747.6 KEZ44114.1 - 0.0056 16.9 8.6 0.023 14.9 6.6 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) CRISPR_Cse2 PF09485.10 KEZ44114.1 - 0.0076 16.8 2.3 0.034 14.7 2.3 2.2 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) DHR10 PF18595.1 KEZ44114.1 - 0.0079 16.3 7.8 0.0079 16.3 7.8 2.2 2 1 0 2 2 2 1 Designed helical repeat protein 10 domain Zwint PF15556.6 KEZ44114.1 - 0.029 13.9 10.5 0.19 11.2 9.8 2.4 2 1 0 2 2 2 0 ZW10 interactor DUF1664 PF07889.12 KEZ44114.1 - 0.033 14.2 1.5 0.12 12.4 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KEZ44114.1 - 0.078 13.1 5.7 5.4 7.1 5.7 2.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.8 KEZ44114.1 - 0.45 10.5 6.9 1.5 8.8 6.9 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HTH_53 PF18606.1 KEZ44114.1 - 1 9.1 3.3 2.2 8.0 1.2 2.5 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain HSCB_C PF07743.13 KEZ44114.1 - 2.8 8.5 6.4 4.2 7.9 3.8 2.8 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain GrpE PF01025.19 KEZ44114.1 - 3.2 7.4 8.9 11 5.6 8.1 2.1 1 1 1 2 2 2 0 GrpE DUF4763 PF15960.5 KEZ44114.1 - 7.8 5.7 11.3 21 4.3 11.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Mito_carr PF00153.27 KEZ44115.1 - 2e-58 194.3 2.0 4.8e-21 74.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_trans_2_3 PF13632.6 KEZ44116.1 - 9.5e-49 166.0 4.3 2.7e-48 164.5 4.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KEZ44116.1 - 3.6e-07 30.1 0.1 4.5e-05 23.3 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KEZ44116.1 - 6.6e-05 22.5 0.1 0.00028 20.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Peptidase_C48 PF02902.19 KEZ44117.1 - 3.8e-31 108.6 0.0 9.2e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Proteasome PF00227.26 KEZ44118.1 - 6.5e-35 120.3 0.0 7.9e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit AMP-binding PF00501.28 KEZ44119.1 - 2.2e-18 66.0 0.0 3.3e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Lysine_decarbox PF03641.14 KEZ44120.1 - 9.9e-27 93.6 0.0 1.5e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KEZ44120.1 - 2.1e-05 24.1 0.1 0.0009 18.9 0.0 2.2 2 0 0 2 2 2 2 SLOG cluster4 family LSDAT_prok PF18171.1 KEZ44120.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Proteasome PF00227.26 KEZ44121.1 - 1e-46 158.9 0.1 1.3e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KEZ44121.1 - 1.5e-11 43.7 0.3 2.7e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 KEZ44122.1 - 8.7e-46 154.7 8.2 9.8e-46 154.5 8.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TRAPPC9-Trs120 PF08626.11 KEZ44123.1 - 0 1396.7 0.0 0 1396.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ASH PF15780.5 KEZ44123.1 - 0.021 15.0 0.5 0.47 10.7 0.0 2.5 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin adh_short PF00106.25 KEZ44124.1 - 1.3e-19 70.4 0.0 2.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ44124.1 - 1.8e-16 60.4 0.0 2.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KEZ44124.1 - 0.088 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.10 KEZ44124.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 KR domain Sugar_tr PF00083.24 KEZ44125.1 - 4.3e-108 362.1 18.1 5.8e-108 361.7 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ44125.1 - 1.6e-17 63.5 35.4 2.6e-17 62.8 26.2 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 KEZ44126.1 - 6.3e-135 449.8 0.1 8.3e-135 449.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) LysM PF01476.20 KEZ44126.1 - 0.032 14.3 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 LysM domain Glyco_hydro_63 PF03200.16 KEZ44127.1 - 1.2e-171 571.9 0.5 1.7e-170 568.0 0.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KEZ44127.1 - 1e-76 258.0 0.0 2.4e-76 256.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KEZ44127.1 - 3.6e-05 22.8 0.1 7e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Trehalase MnmE_helical PF12631.7 KEZ44128.1 - 1.8e-30 106.7 0.1 2.3e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KEZ44128.1 - 9.5e-20 70.8 0.0 1.7e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ44128.1 - 3.6e-07 29.8 0.0 3.9e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KEZ44128.1 - 7.3e-06 26.1 0.0 3.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Dynamin family TrmE_N PF10396.9 KEZ44128.1 - 1.2e-05 25.6 0.1 3.8e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus RsgA_GTPase PF03193.16 KEZ44128.1 - 0.00011 22.1 0.2 0.06 13.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KEZ44128.1 - 0.0049 16.4 0.0 0.53 9.8 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 KEZ44128.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ44128.1 - 0.039 14.5 0.1 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 KEZ44128.1 - 0.046 14.0 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEZ44128.1 - 0.079 12.6 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Ras family Ribosomal_L28e PF01778.17 KEZ44129.1 - 2.4e-39 134.7 2.3 2.4e-39 134.7 2.3 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KEZ44129.1 - 5.6e-27 94.3 13.4 5.6e-27 94.3 13.4 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KEZ44129.1 - 3.8e-08 33.1 20.9 4.9e-08 32.7 20.9 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 KEZ44129.1 - 0.026 13.2 36.1 0.037 12.6 36.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.18 KEZ44129.1 - 0.085 12.6 2.6 0.095 12.4 1.5 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain Rgp1 PF08737.10 KEZ44129.1 - 0.12 11.6 4.5 0.16 11.1 4.5 1.2 1 0 0 1 1 1 0 Rgp1 SDA1 PF05285.12 KEZ44129.1 - 0.28 10.6 30.6 0.38 10.1 30.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEZ44129.1 - 5.1 5.2 36.0 7.6 4.6 36.0 1.2 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.17 KEZ44129.1 - 8.9 6.4 7.0 24 5.0 7.0 1.8 1 1 0 1 1 1 0 DDHD domain RabGAP-TBC PF00566.18 KEZ44130.1 - 4.8e-36 124.4 3.3 1.4e-35 122.9 3.3 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KEZ44130.1 - 6.9e-07 28.9 0.0 0.011 15.2 0.0 3.3 3 0 0 3 3 3 3 Rab-binding domain (RBD) adh_short_C2 PF13561.6 KEZ44131.1 - 8.5e-50 169.5 0.0 1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ44131.1 - 1.7e-37 128.8 0.0 2.4e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ44131.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Med6 PF04934.14 KEZ44132.1 - 2.4e-38 130.9 0.0 3.1e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component FbpC_C_terminal PF17845.1 KEZ44132.1 - 0.0055 16.8 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 2 FbpC C-terminal regulatory nucleotide binding domain Telomerase_RBD PF12009.8 KEZ44133.1 - 0.087 12.9 0.2 0.2 11.7 0.1 1.4 1 1 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Pkinase PF00069.25 KEZ44134.1 - 5.7e-36 124.2 0.0 9.2e-31 107.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44134.1 - 1.1e-16 60.9 0.0 2.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ44134.1 - 0.005 16.8 0.1 0.021 14.8 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family ERF PF04404.12 KEZ44134.1 - 0.19 11.6 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 ERF superfamily Exo_endo_phos PF03372.23 KEZ44135.1 - 8e-10 38.6 0.2 1.3e-09 37.9 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.9 KEZ44135.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain SdpI PF13630.6 KEZ44135.1 - 0.085 13.0 0.4 0.2 11.8 0.4 1.6 1 0 0 1 1 1 0 SdpI/YhfL protein family YbgT_YccB PF08173.11 KEZ44135.1 - 3.7 7.8 5.9 1 9.5 2.1 2.1 2 0 0 2 2 2 0 Membrane bound YbgT-like protein WD40 PF00400.32 KEZ44136.1 - 3.1e-53 176.6 18.4 2e-10 41.1 1.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ44136.1 - 3.8e-20 72.0 0.0 0.0018 18.5 0.0 6.2 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ44136.1 - 1.8e-08 33.7 0.1 0.9 8.4 0.0 5.0 2 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEZ44136.1 - 3.6e-07 29.2 0.4 0.049 12.3 0.1 4.1 2 2 2 4 4 4 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 KEZ44136.1 - 8.5e-05 21.8 1.0 3.2 6.8 0.0 3.9 2 1 1 4 4 4 2 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 KEZ44136.1 - 8.6e-05 21.4 0.5 0.12 11.1 0.0 3.6 1 1 2 3 3 3 2 Nup133 N terminal like VID27 PF08553.10 KEZ44136.1 - 0.0079 15.3 0.1 0.6 9.1 0.0 3.6 2 1 4 6 6 6 1 VID27 C-terminal WD40-like domain WD40_like PF17005.5 KEZ44136.1 - 0.02 14.2 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Frtz PF11768.8 KEZ44136.1 - 0.025 12.9 0.0 1.2 7.4 0.0 2.4 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 KEZ44136.1 - 0.11 10.5 0.0 0.25 9.3 0.0 1.5 1 1 1 2 2 2 0 IKI3 family zf-UBR PF02207.20 KEZ44137.1 - 1.7e-18 66.6 14.8 4.2e-18 65.3 14.8 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KEZ44137.1 - 2.4e-07 30.4 0.2 7.3e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.12 KEZ44138.1 - 2.4e-23 81.8 1.9 4.9e-23 80.8 1.9 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Vut_1 PF02592.15 KEZ44138.1 - 0.0064 16.8 1.2 0.0064 16.8 1.2 3.3 3 1 1 4 4 4 2 Putative vitamin uptake transporter Vpu PF00558.19 KEZ44138.1 - 3.5 7.5 4.7 3.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Vpu protein SCAMP PF04144.13 KEZ44138.1 - 9.1 6.6 13.7 0.16 12.3 4.5 2.5 3 0 0 3 3 3 0 SCAMP family Cation_ATPase_C PF00689.21 KEZ44139.1 - 1.2e-46 158.7 5.8 2.2e-46 157.9 1.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEZ44139.1 - 2e-36 125.2 0.4 2e-36 125.2 0.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KEZ44139.1 - 1.9e-22 79.1 0.0 4.2e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ44139.1 - 1.3e-17 64.8 0.6 3.3e-17 63.5 0.6 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ44139.1 - 2.8e-09 36.5 0.0 2.6e-07 30.2 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ44139.1 - 7.2e-06 25.9 0.6 0.0002 21.2 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KEZ44139.1 - 0.0031 16.4 0.9 0.0031 16.4 0.9 1.7 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG AgrB PF04647.15 KEZ44139.1 - 2 7.7 4.1 0.74 9.1 0.0 2.3 3 0 0 3 3 3 0 Accessory gene regulator B Phage_holin_3_6 PF07332.11 KEZ44139.1 - 5.6 7.0 8.2 0.36 10.9 0.1 3.0 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III RWD PF05773.22 KEZ44140.1 - 5.9e-24 84.6 0.6 1e-23 83.8 0.6 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KEZ44140.1 - 6e-08 33.1 6.1 1.1e-07 32.2 6.1 1.4 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 UQ_con PF00179.26 KEZ44140.1 - 0.0019 17.9 0.1 0.0059 16.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UPF0564 PF10595.9 KEZ44140.1 - 0.018 14.1 2.9 0.026 13.6 2.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF2852 PF11014.8 KEZ44140.1 - 0.12 12.6 1.1 0.18 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Lum_binding PF00677.17 KEZ44141.1 - 3.7e-43 145.4 0.4 3.1e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain ATP-synt_DE_N PF02823.16 KEZ44141.1 - 0.025 14.5 0.0 0.083 12.8 0.0 1.9 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PGM_PMM_I PF02878.16 KEZ44142.1 - 6.8e-17 61.5 0.3 7.4e-08 32.2 0.0 3.6 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KEZ44142.1 - 2.2e-11 43.8 0.4 7.7e-11 42.0 0.4 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 KEZ44142.1 - 0.0025 18.4 0.3 0.088 13.4 0.3 2.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KEZ44142.1 - 0.0032 17.6 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_25 PF13649.6 KEZ44143.1 - 4.7e-11 43.3 0.0 1.3e-10 41.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KEZ44143.1 - 1e-09 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KEZ44143.1 - 1.6e-09 37.7 0.1 6.6e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44143.1 - 1.4e-07 32.0 0.0 3.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KEZ44143.1 - 3.1e-06 26.4 0.1 4.5e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 KEZ44143.1 - 3.8e-05 24.3 0.0 8.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ44143.1 - 6.4e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KEZ44143.1 - 0.00048 20.1 0.1 0.0009 19.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ44143.1 - 0.00073 19.1 0.3 0.0025 17.4 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KEZ44143.1 - 0.0013 18.1 0.2 0.0029 16.9 0.2 1.6 1 1 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KEZ44143.1 - 0.0021 17.4 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 KEZ44143.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 KEZ44143.1 - 0.033 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KEZ44144.1 - 8.1e-60 202.4 0.0 2.7e-37 128.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44144.1 - 2.6e-28 99.0 0.0 3.6e-20 72.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KEZ44144.1 - 6.5e-15 55.3 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KEZ44144.1 - 4.2e-07 29.6 0.1 0.0005 19.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KEZ44144.1 - 0.00023 21.1 0.0 0.035 14.0 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 KEZ44144.1 - 0.0045 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 KEZ44144.1 - 0.023 13.6 0.2 0.042 12.8 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KEZ44144.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KEZ44144.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Acyltransferase PF01553.21 KEZ44145.1 - 1.4e-13 50.7 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KEZ44145.1 - 3.9e-10 39.7 2.2 4.4e-10 39.5 0.5 1.9 2 0 0 2 2 2 1 Acyltransferase C-terminus PAP1 PF08601.10 KEZ44146.1 - 0.067 12.9 7.1 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 bZIP_1 PF00170.21 KEZ44146.1 - 0.08 13.0 4.9 0.17 12.0 4.9 1.5 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 KEZ44146.1 - 0.093 13.1 0.5 0.21 11.9 0.5 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family eIF-3_zeta PF05091.12 KEZ44147.1 - 5.2e-204 679.0 0.0 6.2e-204 678.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KEZ44147.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF569) KH_8 PF17903.1 KEZ44148.1 - 7.1e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KEZ44148.1 - 0.012 15.4 0.4 0.025 14.4 0.4 1.5 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 KEZ44149.1 - 6.7e-166 553.0 0.0 8e-166 552.8 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HET PF06985.11 KEZ44150.1 - 1.1e-24 87.4 0.4 1.8e-24 86.7 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fur_reg_FbpA PF13076.6 KEZ44150.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Fur-regulated basic protein A zf-H2C2_2 PF13465.6 KEZ44152.1 - 8.3e-13 48.1 8.0 1.9e-07 31.2 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KEZ44152.1 - 3.3e-12 46.1 16.8 3.6e-06 27.1 2.4 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ44152.1 - 1.3e-08 35.0 12.8 0.0004 21.0 1.5 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KEZ44152.1 - 2.7e-08 33.6 5.4 0.00032 20.6 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ44152.1 - 1.4e-06 28.4 1.3 0.087 13.1 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ44152.1 - 3.5e-05 24.0 2.9 0.013 15.9 0.2 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KEZ44152.1 - 0.0072 16.1 5.4 0.41 10.5 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 KEZ44152.1 - 0.041 14.4 0.8 0.086 13.4 0.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 KEZ44152.1 - 0.069 13.5 1.4 0.13 12.5 1.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.22 KEZ44152.1 - 0.48 10.7 3.6 18 5.7 0.1 2.4 1 1 1 2 2 2 0 LIM domain zf-C2HE PF16278.5 KEZ44152.1 - 0.87 10.1 3.7 12 6.5 0.3 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 KEZ44152.1 - 2.2 8.5 5.2 4.2 7.6 5.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger C5HCH PF17982.1 KEZ44152.1 - 4 7.7 6.7 25 5.1 1.1 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain AOX PF01786.17 KEZ44153.1 - 7.2e-76 254.5 0.0 8.6e-76 254.3 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase RFX_DNA_binding PF02257.15 KEZ44154.1 - 0.098 13.3 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain RhodobacterPufX PF11511.8 KEZ44154.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.4 2 0 0 2 2 2 0 Intrinsic membrane protein PufX eIF3_subunit PF08597.10 KEZ44155.1 - 9.3e-74 248.4 26.3 1.2e-73 248.0 26.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop53 PF07767.11 KEZ44155.1 - 0.42 10.0 25.9 0.33 10.3 17.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PRP4 PF08799.11 KEZ44155.1 - 0.86 9.2 3.7 1.9 8.1 3.7 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Per1 PF04080.13 KEZ44157.1 - 9.4e-104 346.7 10.1 1.2e-103 346.4 10.1 1.1 1 0 0 1 1 1 1 Per1-like family FAM70 PF14967.6 KEZ44157.1 - 0.058 12.9 0.4 0.082 12.4 0.4 1.1 1 0 0 1 1 1 0 FAM70 protein DUF4805 PF16063.5 KEZ44158.1 - 0.054 12.8 2.4 0.083 12.2 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) HLH PF00010.26 KEZ44159.1 - 5.8e-13 48.6 0.4 1.1e-12 47.7 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5583 PF17821.1 KEZ44159.1 - 1.1 9.2 5.3 0.24 11.4 1.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5583) FAM199X PF15814.5 KEZ44159.1 - 5.9 5.8 14.0 16 4.4 14.0 1.7 1 0 0 1 1 1 0 Protein family FAM199X Miga PF10265.9 KEZ44159.1 - 9.9 5.0 8.7 13 4.6 8.7 1.3 1 0 0 1 1 1 0 Mitoguardin Aldedh PF00171.22 KEZ44160.1 - 3.5e-113 378.6 0.0 4.4e-113 378.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BcsB PF03170.13 KEZ44160.1 - 0.083 11.2 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit PhoD PF09423.10 KEZ44161.1 - 1.7e-05 24.0 0.3 0.0046 16.0 0.1 2.7 3 0 0 3 3 3 2 PhoD-like phosphatase Ank_2 PF12796.7 KEZ44162.1 - 8.8e-40 135.2 1.2 1.9e-12 47.6 0.0 9.0 8 1 1 9 9 9 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ44162.1 - 2.3e-32 107.4 1.1 0.0021 18.4 0.0 12.4 12 0 0 12 12 12 5 Ankyrin repeat Ank_4 PF13637.6 KEZ44162.1 - 6.5e-30 103.1 2.5 5e-05 23.8 0.0 10.2 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 KEZ44162.1 - 1.6e-24 85.2 9.2 0.00065 20.0 0.0 11.2 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 KEZ44162.1 - 2.7e-16 59.4 3.9 0.00038 20.7 0.1 7.6 8 1 1 9 9 9 5 Ankyrin repeats (many copies) DUF4746 PF15928.5 KEZ44162.1 - 2.5 7.4 15.1 4.2 6.7 11.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PPL5 PF18168.1 KEZ44162.1 - 3.1 7.0 6.0 8.5 5.6 6.0 1.6 1 0 0 1 1 1 0 Prim-pol family 5 CFEM PF05730.11 KEZ44163.1 - 1.7e-12 47.2 13.6 2.6e-12 46.6 13.6 1.3 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.16 KEZ44164.1 - 3.8e-32 111.6 31.3 3.8e-32 111.6 31.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ44164.1 - 1.9e-08 33.7 13.1 1.9e-08 33.7 13.1 3.3 2 2 0 3 3 3 1 Sugar (and other) transporter DUF1772 PF08592.11 KEZ44165.1 - 0.00029 21.1 10.0 0.0011 19.2 10.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) RGM_C PF06534.13 KEZ44165.1 - 0.045 13.3 0.2 0.066 12.7 0.2 1.2 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus adh_short_C2 PF13561.6 KEZ44166.1 - 3.3e-37 128.3 0.4 4.8e-37 127.8 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ44166.1 - 2.2e-31 108.9 0.9 3.3e-31 108.3 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ44166.1 - 2e-08 34.3 1.1 9e-08 32.2 0.2 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KEZ44166.1 - 0.0052 16.0 0.1 0.007 15.5 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KEZ44166.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TRP PF06011.12 KEZ44167.1 - 2.2e-36 125.5 18.7 8.4e-29 100.5 7.7 2.1 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KEZ44167.1 - 1.1e-23 84.1 0.0 1.7e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 ML-like domain PWI PF01480.17 KEZ44168.1 - 1.9e-31 108.1 0.1 6.7e-31 106.4 0.1 2.0 1 0 0 1 1 1 1 PWI domain DNA_mis_repair PF01119.19 KEZ44168.1 - 1.1e-13 50.9 0.0 2.2e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KEZ44168.1 - 0.0036 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nas2_N PF18265.1 KEZ44169.1 - 8.8e-31 105.7 0.2 1.2e-30 105.2 0.2 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KEZ44169.1 - 5.1e-08 32.6 0.5 4.1e-07 29.8 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 KEZ44169.1 - 4.7e-06 26.8 0.0 9.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KEZ44169.1 - 3.8e-05 23.9 0.0 7.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 KEZ44170.1 - 8.8e-49 165.2 0.0 1.1e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ44170.1 - 3.8e-29 101.4 0.0 9.6e-29 100.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ44170.1 - 5.7e-10 38.9 0.0 7.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEZ44170.1 - 0.00035 20.6 0.0 0.00065 19.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KEZ44170.1 - 0.00057 20.3 0.1 0.0046 17.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KEZ44170.1 - 0.0067 15.8 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KEZ44170.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KEZ44170.1 - 0.026 14.5 0.1 7.7 6.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KEZ44170.1 - 0.027 14.0 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 KEZ44170.1 - 0.033 13.4 1.9 1.3 8.1 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 KEZ44170.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KEZ44170.1 - 0.089 12.8 0.1 0.19 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KEZ44170.1 - 0.093 13.1 0.1 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 KEZ44170.1 - 0.1 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KEZ44170.1 - 0.21 10.8 0.7 0.31 10.3 0.1 1.5 2 0 0 2 2 2 0 Septin Peptidase_S10 PF00450.22 KEZ44171.1 - 2.6e-52 178.7 0.0 5.6e-26 91.9 0.2 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase Pep3_Vps18 PF05131.14 KEZ44171.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family Homeodomain PF00046.29 KEZ44172.1 - 1.1e-12 47.6 0.5 1.1e-12 47.6 0.5 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 KEZ44172.1 - 0.094 12.6 0.3 0.28 11.1 0.3 1.8 1 0 0 1 1 1 0 Homeobox KN domain NAD_kinase PF01513.21 KEZ44173.1 - 8.2e-80 268.1 0.0 1.2e-79 267.6 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 KEZ44174.1 - 0.00042 20.8 0.0 0.0011 19.5 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEZ44174.1 - 0.028 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 HalOD1 PF18545.1 KEZ44174.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Halobacterial output domain 1 MaoC_dehydratas PF01575.19 KEZ44175.1 - 9e-23 80.2 0.0 1.5e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain dCMP_cyt_deam_1 PF00383.23 KEZ44176.1 - 1.7e-08 34.3 0.4 1.2e-06 28.3 0.4 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KEZ44176.1 - 0.00077 19.1 2.0 0.044 13.4 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sugar_tr PF00083.24 KEZ44177.1 - 5.5e-97 325.5 30.6 7.2e-97 325.1 30.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ44177.1 - 4.6e-20 71.9 36.0 6.9e-20 71.3 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ44177.1 - 0.00014 20.4 0.8 0.00014 20.4 0.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) HisG PF01634.18 KEZ44178.1 - 8.8e-55 185.0 0.0 1.4e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KEZ44178.1 - 3e-29 100.9 0.8 6.2e-29 100.0 0.8 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KEZ44178.1 - 0.11 12.4 0.0 8.5 6.2 0.0 2.5 2 1 0 2 2 2 0 NMT1/THI5 like STT3 PF02516.14 KEZ44180.1 - 1.7e-141 472.5 33.8 6.2e-137 457.5 31.4 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 KEZ44181.1 - 1.1e-23 83.4 0.1 1.2e-23 83.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain Halogen_Hydrol PF10112.9 KEZ44181.1 - 0.093 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein WD40 PF00400.32 KEZ44182.1 - 4.9e-07 30.4 6.3 0.35 11.8 1.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat Sec20 PF03908.13 KEZ44182.1 - 0.35 10.8 1.8 3 7.8 1.3 2.2 1 1 1 2 2 2 0 Sec20 DUF726 PF05277.12 KEZ44183.1 - 1.6e-126 421.8 2.3 2.3e-126 421.4 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SKG6 PF08693.10 KEZ44184.1 - 0.0057 16.0 2.2 0.012 15.1 2.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KEZ44184.1 - 0.056 13.4 1.2 0.16 11.9 1.2 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif VSP PF03302.13 KEZ44184.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF3188 PF11384.8 KEZ44184.1 - 0.14 11.9 1.5 0.32 10.7 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF347 PF03988.12 KEZ44184.1 - 0.2 11.9 1.1 0.4 10.9 1.1 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF3611 PF12263.8 KEZ44184.1 - 0.22 11.4 0.6 0.4 10.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) VPDSG-CTERM PF18205.1 KEZ44184.1 - 1.1 9.1 7.6 2.4 8.1 7.6 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif DUF846 PF05832.12 KEZ44185.1 - 3.4e-40 137.3 4.1 4.1e-40 137.0 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.6 KEZ44185.1 - 0.12 11.7 1.8 0.16 11.3 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) HpcH_HpaI PF03328.14 KEZ44186.1 - 4.6e-42 143.6 0.0 5.9e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KEZ44186.1 - 9.3e-16 57.9 0.0 2e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 KEZ44186.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain BLACT_WH PF17778.1 KEZ44186.1 - 0.36 10.8 1.8 0.37 10.8 0.1 1.8 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain RRM_1 PF00076.22 KEZ44188.1 - 1.8e-23 82.2 0.0 2.3e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ44188.1 - 0.00049 20.2 0.0 0.00086 19.4 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 KEZ44188.1 - 0.024 14.5 0.0 0.038 13.8 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif PAP_PilO PF06864.12 KEZ44188.1 - 0.079 11.8 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) ChaC PF04752.12 KEZ44189.1 - 3.8e-37 128.1 0.0 5.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.32 KEZ44190.1 - 9.9e-27 90.5 4.1 1.2e-06 27.7 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 KEZ44190.1 - 1.5e-23 83.0 2.5 6.4e-11 42.6 0.0 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KEZ44190.1 - 4.5e-22 76.0 3.5 0.0015 18.3 0.0 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 KEZ44190.1 - 2.2e-19 69.0 6.6 5.7e-11 42.1 0.0 4.8 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KEZ44190.1 - 4.3e-17 60.7 1.3 0.0016 17.9 0.0 4.5 4 0 0 4 4 4 4 EF hand Hep_59 PF07052.11 KEZ44192.1 - 1.1e-14 55.0 2.6 7e-14 52.5 0.1 3.1 2 2 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 ChapFlgA PF13144.6 KEZ44192.1 - 0.023 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation WD40 PF00400.32 KEZ44194.1 - 1.3e-16 60.6 8.6 0.00088 20.0 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ44194.1 - 6e-06 26.5 1.0 0.0084 16.4 0.2 4.1 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ44194.1 - 9.7e-06 24.5 0.8 0.0001 21.1 0.2 2.5 2 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KEZ44194.1 - 0.0062 15.3 0.1 1.1 7.9 0.1 2.9 2 1 1 3 3 3 2 Nup133 N terminal like LZ_Tnp_IS66 PF13007.7 KEZ44194.1 - 0.46 11.3 5.5 0.86 10.4 2.3 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Cys_Met_Meta_PP PF01053.20 KEZ44195.1 - 7e-60 202.6 0.0 1.5e-59 201.5 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2417 PF10329.9 KEZ44197.1 - 8.4e-79 264.3 2.1 1.2e-78 263.8 2.1 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2070 PF09843.9 KEZ44197.1 - 0.71 8.1 6.9 0.99 7.6 6.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RhoGAP PF00620.27 KEZ44198.1 - 2.6e-35 121.5 0.0 6.7e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KEZ44198.1 - 5e-30 103.5 38.3 3e-12 46.6 6.3 4.9 5 0 0 5 5 5 4 LIM domain Mfa1 PF17445.2 KEZ44198.1 - 0.027 14.5 0.1 0.073 13.1 0.1 1.8 1 0 0 1 1 1 0 Mating factor A1 3Beta_HSD PF01073.19 KEZ44199.1 - 4.2e-64 216.3 0.0 5.2e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEZ44199.1 - 9.1e-34 117.0 0.7 1.3e-33 116.5 0.3 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ44199.1 - 1.9e-17 63.3 0.1 2.6e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEZ44199.1 - 5.4e-15 55.6 0.1 6.5e-14 52.1 0.2 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ44199.1 - 2.5e-11 43.2 1.4 6.1e-09 35.4 0.2 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KEZ44199.1 - 3.3e-10 40.2 0.1 4.7e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEZ44199.1 - 4.3e-08 32.6 2.3 1.6e-07 30.8 1.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KEZ44199.1 - 0.00036 20.2 0.4 0.00076 19.1 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family DUF3798 PF12683.7 KEZ44199.1 - 0.0068 15.9 0.2 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3798) KR PF08659.10 KEZ44199.1 - 0.049 13.5 5.5 3.5 7.5 4.9 2.8 1 1 1 2 2 2 0 KR domain HMG_box PF00505.19 KEZ44200.1 - 2e-10 40.9 0.3 2e-10 40.9 0.3 2.8 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEZ44200.1 - 1.9e-08 34.7 2.0 1.7e-07 31.8 0.5 2.8 2 0 0 2 2 2 1 HMG-box domain Imm58 PF15581.6 KEZ44200.1 - 0.0018 18.4 0.1 0.004 17.2 0.1 1.5 1 0 0 1 1 1 1 Immunity protein 58 SspB PF04386.13 KEZ44200.1 - 0.33 10.8 3.5 0.67 9.8 3.5 1.5 1 0 0 1 1 1 0 Stringent starvation protein B Proteasome PF00227.26 KEZ44201.1 - 1.1e-26 93.4 0.0 1.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SIS PF01380.22 KEZ44202.1 - 3.1e-59 198.5 0.1 2.1e-31 108.5 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KEZ44202.1 - 1e-17 64.6 0.0 1.9e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KEZ44202.1 - 4.3e-10 39.6 0.0 9.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KEZ44202.1 - 0.005 15.8 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA PF00004.29 KEZ44203.1 - 5.5e-43 146.6 0.0 1.2e-42 145.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEZ44203.1 - 2.5e-12 46.6 0.1 3.2e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KEZ44203.1 - 8.9e-10 38.2 0.8 1.9e-09 37.2 0.1 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KEZ44203.1 - 4.2e-08 33.8 0.0 2.3e-05 24.8 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KEZ44203.1 - 1.5e-06 28.3 0.1 3.8e-05 23.7 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEZ44203.1 - 3.9e-06 27.1 0.0 9.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KEZ44203.1 - 6.6e-06 26.0 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ44203.1 - 0.0002 21.6 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ44203.1 - 0.00065 20.2 0.3 0.0028 18.2 0.0 2.2 3 1 0 3 3 1 1 AAA domain DUF815 PF05673.13 KEZ44203.1 - 0.00065 18.9 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KEZ44203.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KEZ44203.1 - 0.0021 17.6 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KEZ44203.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 KEZ44203.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 KEZ44203.1 - 0.0039 17.4 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEZ44203.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEZ44203.1 - 0.0053 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEZ44203.1 - 0.006 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KEZ44203.1 - 0.0063 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KEZ44203.1 - 0.0083 15.8 0.0 0.026 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KEZ44203.1 - 0.0097 15.8 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KEZ44203.1 - 0.027 13.8 0.5 0.15 11.4 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 KEZ44203.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ44203.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ44203.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 KEZ44203.1 - 0.06 13.1 0.2 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEZ44203.1 - 0.061 13.2 0.0 0.28 11.1 0.0 2.2 2 1 0 2 2 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 KEZ44203.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KEZ44203.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ44203.1 - 0.088 12.4 0.3 0.23 11.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KEZ44203.1 - 0.096 12.0 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 KEZ44203.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 OmpH PF03938.14 KEZ44203.1 - 0.72 10.2 3.9 1.4 9.2 0.9 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 KEZ44203.1 - 0.72 10.3 6.9 0.12 12.7 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) KAR9 PF08580.10 KEZ44204.1 - 3.6e-176 587.7 6.4 3.6e-176 587.7 6.4 2.2 2 0 0 2 2 2 1 Yeast cortical protein KAR9 PLU-1 PF08429.11 KEZ44204.1 - 0.048 12.8 4.7 0.073 12.2 0.0 2.7 2 1 1 3 3 3 0 PLU-1-like protein Syntaxin-6_N PF09177.11 KEZ44204.1 - 0.097 13.2 9.3 1.8 9.1 1.5 4.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 KEZ44204.1 - 0.11 13.0 5.4 5.1 7.6 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DNA_photolyase PF00875.18 KEZ44204.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA photolyase FliT PF05400.13 KEZ44204.1 - 0.18 12.6 5.1 1.8 9.5 0.1 3.7 3 0 0 3 3 3 0 Flagellar protein FliT DHR10 PF18595.1 KEZ44204.1 - 0.61 10.2 2.9 1.4 9.0 0.1 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Fib_alpha PF08702.10 KEZ44204.1 - 0.82 9.8 2.7 1.9 8.7 0.3 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 KEZ44204.1 - 1.1 9.3 2.7 6.8 6.7 0.1 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DEAD PF00270.29 KEZ44205.1 - 7.2e-20 71.5 0.0 1.4e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ44205.1 - 1.9e-16 60.4 0.0 1e-14 54.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KEZ44205.1 - 3.2e-16 59.8 1.9 7.7e-16 58.6 1.9 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KEZ44205.1 - 2.2e-12 46.7 0.4 2.7e-11 43.3 0.4 2.4 1 1 0 1 1 1 1 RQC domain ResIII PF04851.15 KEZ44205.1 - 2.1e-07 31.1 0.1 8.9e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KEZ44205.1 - 1.5e-05 24.9 0.4 4.7e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 HRDC domain DUF4407 PF14362.6 KEZ44205.1 - 1.6 8.0 5.0 11 5.3 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GPI-anchored PF10342.9 KEZ44206.1 - 5.6e-20 71.9 0.0 1.2e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KEZ44206.1 - 0.0038 17.0 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Cohesin PF00963.18 KEZ44206.1 - 0.063 13.5 0.0 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Cohesin domain ABM PF03992.16 KEZ44207.1 - 4.5e-06 26.7 0.1 0.00067 19.7 0.1 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF3764 PF12594.8 KEZ44207.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) HCV_NS4a PF01006.20 KEZ44207.1 - 0.077 12.8 1.5 0.079 12.7 0.4 1.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a DUF4188 PF13826.6 KEZ44207.1 - 0.09 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) KH_1 PF00013.29 KEZ44208.1 - 3.4e-43 145.3 6.3 9.7e-18 63.8 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KEZ44208.1 - 3.2e-12 46.1 4.0 0.0032 17.3 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KEZ44208.1 - 9.3e-06 25.4 1.1 0.43 10.5 0.0 3.4 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 KEZ44208.1 - 2.7e-05 24.1 0.0 0.004 17.1 0.0 2.5 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KEZ44208.1 - 0.00014 21.9 8.5 0.14 12.3 0.2 3.5 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.19 KEZ44209.1 - 6e-45 152.1 0.0 8e-45 151.7 0.0 1.2 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.12 KEZ44210.1 - 6.6e-13 48.6 0.0 9.8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KEZ44210.1 - 3.2e-07 30.0 0.2 1.3e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Ipi1_N PF12333.8 KEZ44210.1 - 0.14 12.7 0.1 0.28 11.8 0.1 1.4 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation CH PF00307.31 KEZ44210.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain PCNA_N PF00705.18 KEZ44211.1 - 6e-55 184.4 7.6 7.3e-55 184.1 5.9 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KEZ44211.1 - 6.9e-50 168.5 0.0 1.5e-49 167.4 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KEZ44211.1 - 3.6e-11 43.0 0.1 4.2e-11 42.8 0.1 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KEZ44211.1 - 6.5e-08 32.0 0.7 2.5e-06 26.7 0.7 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KEZ44211.1 - 5e-06 25.8 0.4 2.2e-05 23.7 0.4 2.2 1 1 0 1 1 1 1 Hus1-like protein p450 PF00067.22 KEZ44212.1 - 8.5e-75 252.3 0.0 1.3e-74 251.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CENP-K PF11802.8 KEZ44213.1 - 1.2e-08 34.9 3.0 0.021 14.4 7.5 2.2 2 0 0 2 2 2 2 Centromere-associated protein K DUF4368 PF14287.6 KEZ44213.1 - 0.015 15.5 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) DUF724 PF05266.14 KEZ44213.1 - 0.017 14.9 14.7 0.068 13.0 3.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 KEZ44213.1 - 0.27 11.8 10.7 1.7 9.2 1.8 3.2 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Sec8_exocyst PF04048.14 KEZ44213.1 - 0.35 10.8 5.6 0.39 10.6 1.3 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DivIC PF04977.15 KEZ44213.1 - 0.65 9.8 16.3 0.18 11.6 6.2 3.1 2 1 1 3 3 3 0 Septum formation initiator Spc7 PF08317.11 KEZ44213.1 - 0.8 8.5 17.3 0.035 13.0 6.2 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein PIN_12 PF16289.5 KEZ44213.1 - 0.84 10.1 4.3 1.4 9.4 1.0 2.5 3 0 0 3 3 3 0 PIN domain USP8_interact PF08941.10 KEZ44213.1 - 0.99 9.2 5.5 4.3 7.1 1.8 2.4 2 0 0 2 2 2 0 USP8 interacting FapA PF03961.13 KEZ44213.1 - 2.8 6.4 9.3 1.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A FAM76 PF16046.5 KEZ44213.1 - 2.9 7.1 6.3 7 5.9 6.3 1.7 1 0 0 1 1 1 0 FAM76 protein Prefoldin PF02996.17 KEZ44213.1 - 4.5 7.2 13.1 0.59 10.1 0.8 3.3 2 1 1 3 3 3 0 Prefoldin subunit DHR10 PF18595.1 KEZ44213.1 - 4.8 7.3 21.1 3.7 7.6 0.8 3.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Ribosomal_L37 PF08561.10 KEZ44215.1 - 8.2e-41 139.3 2.0 1e-40 139.0 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.9 KEZ44216.1 - 0.00076 20.0 0.0 0.00089 19.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 RRM_1 PF00076.22 KEZ44217.1 - 2.8e-34 116.7 4.8 5.1e-17 61.5 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_2 PF13347.6 KEZ44218.1 - 2e-12 46.4 6.5 2e-12 46.4 6.5 1.8 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 KEZ44218.1 - 5.9e-05 22.1 4.5 5.9e-05 22.1 4.5 2.5 3 1 0 3 3 3 1 MFS_1 like family RhoGEF PF00621.20 KEZ44219.1 - 3.4e-30 105.6 0.0 6.8e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KEZ44219.1 - 1.6e-10 41.1 0.5 3.7e-10 39.9 0.5 1.5 1 0 0 1 1 1 1 BAR domain Seryl_tRNA_N PF02403.22 KEZ44219.1 - 3.5 7.9 5.7 2.3 8.5 1.3 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Telomerase_RBD PF12009.8 KEZ44220.1 - 8e-52 174.9 0.3 2.1e-51 173.5 0.3 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KEZ44220.1 - 1.1e-11 44.7 0.0 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.6 KEZ44221.1 - 2e-18 66.4 2.4 7.7e-18 64.6 2.4 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CYSTM PF12734.7 KEZ44222.1 - 0.00035 20.8 57.2 97 3.4 57.2 3.6 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 KEZ44222.1 - 0.3 11.7 9.8 0.33 11.6 9.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 KEZ44222.1 - 3.6 7.5 14.7 5.4 7.0 14.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SH3_9 PF14604.6 KEZ44223.1 - 1e-29 102.1 4.1 1.2e-14 53.8 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KEZ44223.1 - 6.3e-25 86.5 4.6 4.3e-13 48.6 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KEZ44223.1 - 4.6e-19 67.8 0.0 2.6e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 KEZ44223.1 - 1.4e-14 53.9 0.0 3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Fungal_trans PF04082.18 KEZ44224.1 - 1.7e-16 60.1 0.1 2.5e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1636 PF07845.11 KEZ44224.1 - 0.033 14.6 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) zf-C2H2 PF00096.26 KEZ44226.1 - 0.002 18.5 2.6 0.44 11.1 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ44226.1 - 0.029 15.2 1.4 11 7.1 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KEZ44226.1 - 0.13 11.7 1.0 0.24 10.8 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KEZ44226.1 - 2.2 8.5 4.6 0.38 10.9 0.2 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_2 PF13639.6 KEZ44227.1 - 2.3e-10 40.6 3.8 4.2e-10 39.8 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KEZ44227.1 - 1.3e-08 35.0 2.7 1.3e-08 35.0 2.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEZ44227.1 - 4.3e-06 26.7 0.3 8.2e-06 25.8 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 KEZ44227.1 - 9e-05 22.2 5.8 0.00022 21.0 5.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEZ44227.1 - 0.00017 21.4 1.2 0.00034 20.4 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ44227.1 - 0.00046 20.0 2.9 0.00091 19.0 2.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEZ44227.1 - 0.00056 19.7 3.0 0.00095 19.0 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ44227.1 - 0.00066 19.6 2.5 0.0012 18.8 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEZ44227.1 - 0.0011 18.9 2.7 0.0029 17.6 2.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KEZ44227.1 - 0.0074 15.9 0.5 0.016 14.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KEZ44227.1 - 0.097 12.4 1.3 0.21 11.3 1.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KEZ44227.1 - 0.45 10.7 4.8 6.4 7.0 4.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain p450 PF00067.22 KEZ44228.1 - 1.8e-76 257.8 0.0 2.6e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PKcGMP_CC PF16808.5 KEZ44229.1 - 0.00068 19.4 4.3 0.0043 16.9 0.2 3.6 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 KEZ44229.1 - 0.0015 18.6 5.7 0.0015 18.6 5.7 4.9 4 0 0 4 4 4 1 bZIP transcription factor Spc7 PF08317.11 KEZ44229.1 - 0.046 12.6 12.7 0.016 14.1 9.2 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 KEZ44229.1 - 1.3 7.5 23.0 0.012 14.3 13.0 2.5 2 0 0 2 2 2 0 AAA domain DUF5082 PF16888.5 KEZ44229.1 - 4.3 7.6 8.4 19 5.6 8.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF641 PF04859.12 KEZ44229.1 - 5.6 7.3 14.4 5 7.5 0.9 2.8 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) SHE3 PF17078.5 KEZ44229.1 - 8.7 6.0 16.2 0.98 9.1 4.7 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Fungal_trans PF04082.18 KEZ44230.1 - 4.7e-13 48.8 0.0 4.7e-13 48.8 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ44230.1 - 7.3e-09 35.6 10.7 1.2e-08 34.9 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Omp_AT PF11557.8 KEZ44230.1 - 0.16 10.9 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Solitary outer membrane autotransporter beta-barrel domain URO-D PF01208.17 KEZ44231.1 - 3.9e-125 417.6 0.0 4.4e-125 417.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.8 KEZ44232.1 - 1.9e-15 57.2 8.6 3.4e-12 46.8 2.6 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 KEZ44232.1 - 0.72 9.4 5.1 2.2 7.9 0.0 2.8 1 1 2 3 3 3 0 GTP1/OBG MARVEL PF01284.23 KEZ44233.1 - 0.12 12.3 6.1 0.21 11.6 6.1 1.7 1 1 0 1 1 1 0 Membrane-associating domain Velvet PF11754.8 KEZ44234.1 - 2.4e-91 306.1 4.3 5e-91 305.1 0.0 2.1 2 0 0 2 2 2 1 Velvet factor LRR_4 PF12799.7 KEZ44235.1 - 8.8e-12 45.0 7.1 0.0032 17.8 0.2 4.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEZ44235.1 - 1.5e-10 40.7 4.7 0.0026 17.5 2.7 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 KEZ44235.1 - 4.4e-08 32.6 2.6 5 7.4 0.5 6.1 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KEZ44235.1 - 8.9e-05 22.1 1.3 1 8.8 0.3 3.5 1 1 2 3 3 3 2 Leucine-rich repeat CAP_GLY PF01302.25 KEZ44235.1 - 0.0013 18.7 0.1 0.0038 17.2 0.0 1.8 2 0 0 2 2 2 1 CAP-Gly domain Aldo_ket_red PF00248.21 KEZ44236.1 - 4.3e-64 216.5 0.0 4.9e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldolase_II PF00596.21 KEZ44237.1 - 1.3e-44 152.4 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sec20 PF03908.13 KEZ44238.1 - 2.3e-11 43.4 1.5 4.6e-11 42.5 0.5 2.0 2 0 0 2 2 2 1 Sec20 PEP-utilisers_N PF05524.13 KEZ44238.1 - 0.56 10.4 8.3 5 7.3 1.9 3.2 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal FapA PF03961.13 KEZ44238.1 - 0.66 8.5 3.0 0.7 8.4 1.4 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 KEZ44238.1 - 3 7.9 8.5 1.8 8.6 0.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 KEZ44238.1 - 4.5 8.2 14.1 16 6.5 1.1 3.0 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain MRP_L53 PF10780.9 KEZ44239.1 - 1.1e-22 79.9 1.1 1.7e-22 79.3 1.1 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF971 PF06155.12 KEZ44239.1 - 0.042 14.5 0.1 0.059 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Pyrophosphatase PF00719.19 KEZ44240.1 - 9.3e-59 197.8 0.2 1.2e-58 197.5 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase ApoO PF09769.9 KEZ44241.1 - 3.1e-44 150.1 1.1 1.4e-43 148.0 0.1 2.1 2 0 0 2 2 2 1 Apolipoprotein O Dus PF01207.17 KEZ44242.1 - 1.2e-43 149.4 0.8 4.3e-42 144.3 0.4 2.5 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KEZ44242.1 - 0.046 13.1 0.5 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase Peptidase_M61_N PF17899.1 KEZ44242.1 - 0.18 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain Rotamase_2 PF13145.6 KEZ44242.1 - 0.82 10.5 5.0 1.3 9.8 5.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Glutaredoxin PF00462.24 KEZ44244.1 - 6e-12 45.6 0.0 3.3e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 KEZ44244.1 - 0.0024 18.3 0.0 0.0075 16.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF1765 PF08578.10 KEZ44245.1 - 1.3e-41 141.9 3.0 2.5e-41 141.0 3.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Fungal_trans_2 PF11951.8 KEZ44247.1 - 1.4e-05 24.1 1.4 2.6e-05 23.2 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ44247.1 - 0.005 16.9 2.3 0.0088 16.1 2.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.18 KEZ44248.1 - 5.6e-46 157.1 0.2 7.7e-46 156.6 0.2 1.2 1 0 0 1 1 1 1 Brix domain FAM25 PF15825.5 KEZ44248.1 - 0.0034 17.7 2.0 0.006 16.9 1.2 1.8 2 0 0 2 2 2 1 FAM25 family Tubulin PF00091.25 KEZ44249.1 - 2.3e-64 217.2 0.0 3.1e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEZ44249.1 - 2.2e-45 153.9 0.0 3.9e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KEZ44249.1 - 0.00063 19.5 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 KEZ44250.1 - 1.1e-13 50.8 0.5 4e-08 33.0 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 KEZ44251.1 - 3.6e-14 53.3 3.9 3.6e-14 53.3 3.9 2.6 2 2 1 3 3 3 1 Sds3-like Coiled-coil_56 PF09813.9 KEZ44252.1 - 0.0001 22.3 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 KEZ44253.1 - 3.1e-68 229.8 0.2 6.2e-68 228.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) 3Beta_HSD PF01073.19 KEZ44255.1 - 3.1e-19 69.0 0.0 6.4e-18 64.7 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEZ44255.1 - 4.3e-07 29.6 0.1 1e-06 28.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEZ44255.1 - 3.3e-06 26.5 0.0 0.00018 20.8 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KEZ44255.1 - 9e-05 22.4 0.0 0.00044 20.2 0.0 2.1 2 1 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KEZ44255.1 - 0.0066 15.6 0.1 0.014 14.5 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KEZ44255.1 - 0.0097 15.8 0.1 0.023 14.6 0.1 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KEZ44255.1 - 0.15 11.5 0.2 0.47 9.8 0.2 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RAP1 PF07218.11 KEZ44256.1 - 9.4 4.4 6.0 11 4.1 6.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PGM_PMM_I PF02878.16 KEZ44257.1 - 2.2e-33 114.9 0.0 3.2e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KEZ44257.1 - 3.4e-25 88.5 0.0 6.7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KEZ44257.1 - 6e-15 55.7 0.1 1.3e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KEZ44257.1 - 5e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain N6-adenineMlase PF10237.9 KEZ44257.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase DSPn PF14671.6 KEZ44258.1 - 9.2e-43 146.1 0.0 5.4e-39 133.8 0.0 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KEZ44258.1 - 4.2e-17 62.2 0.0 8.5e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEZ44258.1 - 5.2e-07 29.5 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KEZ44258.1 - 0.0011 19.1 0.6 0.0054 16.9 0.0 2.4 3 0 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 KEZ44258.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KEZ44258.1 - 0.034 14.1 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3439 PF11921.8 KEZ44258.1 - 0.058 13.4 1.1 0.18 11.8 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CDKN3 PF05706.12 KEZ44258.1 - 0.063 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) MFS_1 PF07690.16 KEZ44259.1 - 1.9e-37 129.1 46.3 4.7e-36 124.4 46.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Pcc1 PF09341.10 KEZ44259.1 - 2.5e-30 104.4 0.5 4.7e-30 103.5 0.5 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 TRI12 PF06609.13 KEZ44259.1 - 1.3e-10 40.4 13.2 2.1e-10 39.7 13.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HLH PF00010.26 KEZ44260.1 - 1.7e-15 56.7 0.0 4.1e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tropomyosin PF00261.20 KEZ44260.1 - 0.08 12.3 0.8 0.19 11.0 0.8 1.6 1 0 0 1 1 1 0 Tropomyosin ATG11 PF10377.9 KEZ44261.1 - 2.1e-42 144.2 0.0 2.1e-42 144.2 0.0 4.6 5 0 0 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 KEZ44261.1 - 3.1e-05 23.3 9.7 3.1e-05 23.3 9.7 6.2 2 2 3 5 5 5 1 Autophagy protein Apg17 TPR_MLP1_2 PF07926.12 KEZ44261.1 - 0.0003 20.9 14.7 0.0003 20.9 14.7 8.5 6 3 1 8 8 8 3 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 KEZ44261.1 - 0.0022 17.6 29.7 0.0022 17.6 29.7 5.4 3 1 2 5 5 5 1 Mechanosensitive ion channel porin domain Tropomyosin PF00261.20 KEZ44261.1 - 0.0027 17.1 11.4 0.0027 17.1 11.4 8.6 4 2 2 8 8 8 1 Tropomyosin HicA_toxin PF07927.12 KEZ44261.1 - 0.13 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Pox_A_type_inc PF04508.12 KEZ44261.1 - 9 6.3 9.8 0.63 10.0 0.4 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CENP-H PF05837.12 KEZ44262.1 - 3.2e-30 104.8 3.6 3.8e-30 104.6 3.6 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF349 PF03993.12 KEZ44262.1 - 0.00091 19.5 0.4 0.98 9.8 0.1 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF349) Uso1_p115_C PF04871.13 KEZ44262.1 - 0.022 15.1 2.7 0.054 13.9 2.7 1.7 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF818 PF05677.12 KEZ44262.1 - 0.072 12.0 0.2 0.087 11.8 0.2 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) HMG_box PF00505.19 KEZ44263.1 - 1.1e-24 86.6 1.4 1.3e-24 86.3 1.4 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEZ44263.1 - 3.2e-18 66.1 1.8 4.3e-18 65.7 1.8 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KEZ44263.1 - 0.00066 20.2 1.0 0.003 18.1 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KEZ44263.1 - 0.01 15.8 0.3 0.019 14.9 0.3 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 KEZ44263.1 - 0.033 14.2 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain Prp31_C PF09785.9 KEZ44263.1 - 0.047 14.6 2.3 0.057 14.4 2.3 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain Sod_Cu PF00080.20 KEZ44265.1 - 8.6e-11 42.2 0.5 1.5e-10 41.4 0.3 1.6 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) GP67 PF17634.2 KEZ44265.1 - 0.0064 16.9 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 Gene product 67 CVNH PF08881.10 KEZ44266.1 - 1.3e-16 61.2 1.1 1.1e-07 32.5 0.1 2.2 2 0 0 2 2 2 2 CVNH domain Coa1 PF08695.10 KEZ44266.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.6 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 DUF202 PF02656.15 KEZ44268.1 - 0.00018 21.9 3.9 0.00018 21.9 3.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Glyco_hydro_47 PF01532.20 KEZ44269.1 - 1.5e-170 568.0 0.0 1.9e-170 567.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF347 PF03988.12 KEZ44270.1 - 0.007 16.5 0.1 0.84 9.9 0.0 2.4 2 0 0 2 2 2 2 Repeat of Unknown Function (DUF347) Ribosomal_S19 PF00203.21 KEZ44271.1 - 1.6e-34 117.6 0.3 2.2e-34 117.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 C12orf66_like PF09404.10 KEZ44272.1 - 0.06 12.2 0.1 6.6 5.5 0.0 2.0 1 1 1 2 2 2 0 KICSTOR complex C12orf66 like AA_permease PF00324.21 KEZ44274.1 - 2.6e-140 468.2 33.3 3.2e-140 467.9 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ44274.1 - 1.9e-37 129.1 33.1 2.4e-37 128.8 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 KEZ44274.1 - 0.023 13.5 0.6 0.04 12.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) SnoaL_2 PF12680.7 KEZ44275.1 - 0.00076 20.1 0.0 0.0046 17.6 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain Sortilin-Vps10 PF15902.5 KEZ44276.1 - 1.1e-272 904.4 16.0 3.2e-138 461.3 7.1 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KEZ44276.1 - 1.7e-92 308.4 16.5 6.6e-48 163.3 8.4 2.8 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KEZ44276.1 - 4.6e-13 47.0 38.6 0.19 11.9 0.1 11.7 10 0 0 10 10 10 5 BNR/Asp-box repeat BNR_2 PF13088.6 KEZ44276.1 - 2.8e-07 30.1 7.0 0.0067 15.8 0.0 5.5 4 1 2 6 6 6 3 BNR repeat-like domain PSII_BNR PF14870.6 KEZ44276.1 - 0.0092 15.3 8.2 0.93 8.7 0.0 4.9 5 1 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 DUF2561 PF10812.8 KEZ44276.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) CHB_HEX_C PF03174.13 KEZ44276.1 - 0.046 13.7 2.9 0.55 10.3 0.1 4.0 3 1 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain Ni_hydr_CYTB PF01292.20 KEZ44276.1 - 0.1 12.2 0.1 0.47 10.0 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 BNR_6 PF15899.5 KEZ44276.1 - 0.19 11.9 17.5 27 5.2 0.1 8.2 8 0 0 8 8 8 0 BNR-Asp box repeat LAM_C PF12544.8 KEZ44278.1 - 0.00015 21.9 0.0 0.00037 20.7 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 KEZ44278.1 - 0.008 16.6 0.2 0.046 14.1 0.2 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Rhomboid PF01694.22 KEZ44279.1 - 7.4e-26 91.0 10.9 1.3e-25 90.1 10.9 1.4 1 0 0 1 1 1 1 Rhomboid family IU_nuc_hydro PF01156.19 KEZ44280.1 - 2.6e-53 181.6 0.0 5.2e-53 180.6 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ntox5 PF15543.6 KEZ44280.1 - 0.041 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial toxin 5 P34-Arc PF04045.14 KEZ44282.1 - 3.5e-91 305.2 1.5 1.8e-86 289.7 0.4 2.1 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc Rax2 PF12768.7 KEZ44283.1 - 6e-70 235.1 0.2 7.5e-68 228.2 0.0 3.5 3 0 0 3 3 3 1 Cortical protein marker for cell polarity DUF5122 PF17164.4 KEZ44283.1 - 2.3e-05 24.6 13.5 0.0038 17.5 0.1 7.1 6 0 0 6 6 6 2 Domain of unknown function (DUF5122) beta-propeller Kelch_6 PF13964.6 KEZ44283.1 - 0.009 16.3 5.1 37 4.8 0.0 5.8 5 0 0 5 5 5 0 Kelch motif PQQ_3 PF13570.6 KEZ44283.1 - 0.053 14.0 18.7 1.4 9.6 0.8 6.4 6 0 0 6 6 6 0 PQQ-like domain Kelch_4 PF13418.6 KEZ44283.1 - 0.2 11.7 8.2 17 5.5 0.0 5.3 5 0 0 5 5 5 0 Galactose oxidase, central domain zf-C2H2 PF00096.26 KEZ44284.1 - 5.1e-11 42.4 10.9 2.2e-05 24.6 4.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ44284.1 - 1.8e-07 31.3 24.9 5.7e-06 26.5 0.7 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.7 KEZ44284.1 - 5.4e-06 26.6 1.3 1.8e-05 24.9 1.3 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KEZ44284.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KEZ44284.1 - 0.00029 21.4 10.6 0.0013 19.4 3.2 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ44284.1 - 0.00061 20.0 5.8 0.00075 19.7 1.8 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FXMRP1_C_core PF12235.8 KEZ44284.1 - 0.0078 16.9 0.4 0.0078 16.9 0.4 2.0 2 0 0 2 2 2 1 Fragile X-related 1 protein core C terminal zf-C2H2_2 PF12756.7 KEZ44284.1 - 0.022 15.1 1.1 0.022 15.1 1.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SF3b1 PF08920.10 KEZ44285.1 - 1.6e-23 83.5 5.7 1.6e-23 83.5 5.7 2.0 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KEZ44285.1 - 1.7e-10 41.1 7.5 0.13 12.7 0.1 8.5 8 1 3 11 11 11 3 HEAT repeats HEAT_EZ PF13513.6 KEZ44285.1 - 2.5e-10 40.6 3.5 0.02 15.4 0.0 6.9 7 1 1 8 8 7 2 HEAT-like repeat HhH-GPD PF00730.25 KEZ44285.1 - 7.4e-09 36.0 0.0 2.9e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HEAT PF02985.22 KEZ44285.1 - 4.7e-08 32.6 7.3 1 9.8 0.0 9.0 9 0 0 9 9 9 1 HEAT repeat Adaptin_N PF01602.20 KEZ44285.1 - 4.2e-06 25.6 0.1 0.00097 17.8 0.0 3.0 3 1 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.7 KEZ44285.1 - 4.1e-05 23.7 0.8 1.8 8.6 0.0 5.6 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KEZ44285.1 - 0.00017 22.1 0.0 1.3 9.6 0.0 5.0 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 KEZ44285.1 - 0.00058 19.6 0.1 1.2 8.8 0.0 3.8 5 0 0 5 5 5 2 NUC173 domain UNC45-central PF11701.8 KEZ44285.1 - 0.0014 18.6 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central HHH PF00633.23 KEZ44285.1 - 0.0025 17.6 0.0 0.0082 16.0 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF3385 PF11865.8 KEZ44285.1 - 0.004 17.1 1.6 0.22 11.4 0.0 4.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KEZ44285.1 - 0.018 14.6 0.0 2.4 7.7 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal DRIM PF07539.12 KEZ44285.1 - 0.064 11.5 0.3 10 4.3 0.0 3.8 2 1 2 4 4 4 0 Down-regulated in metastasis MMS19_C PF12460.8 KEZ44285.1 - 0.12 11.5 0.0 1.9 7.5 0.0 2.7 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal RRM_1 PF00076.22 KEZ44286.1 - 4e-26 90.6 0.1 4.9e-11 42.3 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S13_N PF08069.12 KEZ44287.1 - 1e-28 99.1 0.1 1.7e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KEZ44287.1 - 2.8e-14 53.1 0.4 3.9e-14 52.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KEZ44287.1 - 0.095 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 'Paired box' domain Dpy-30 PF05186.13 KEZ44288.1 - 1.6e-06 27.7 0.2 5.6e-06 26.0 0.2 1.9 1 1 0 1 1 1 1 Dpy-30 motif APH PF01636.23 KEZ44289.1 - 4.9e-43 147.8 0.0 3.2e-42 145.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KEZ44289.1 - 1.8e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KEZ44289.1 - 0.00013 21.6 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KEZ44289.1 - 0.014 14.3 0.0 0.042 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KEZ44289.1 - 0.06 12.6 0.0 0.59 9.3 0.0 2.3 1 1 0 1 1 1 0 Fructosamine kinase Arrestin_N PF00339.29 KEZ44290.1 - 5.1e-07 29.9 0.0 9.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KEZ44290.1 - 0.01 16.3 0.0 2 8.9 0.0 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain LSM PF01423.22 KEZ44292.1 - 1.2e-18 66.6 0.1 1.5e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEZ44292.1 - 0.00087 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 KEZ44292.1 - 2.3 6.9 6.0 3.1 6.5 6.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RNA_pol_Rpb2_6 PF00562.28 KEZ44293.1 - 2e-112 376.1 0.0 3e-112 375.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Tyrosinase PF00264.20 KEZ44293.1 - 2.7e-49 168.5 7.2 4.9e-49 167.6 7.2 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_3 PF04565.16 KEZ44293.1 - 1.4e-28 98.8 0.0 3.2e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 KEZ44293.1 - 3.5e-28 98.5 0.0 5.8e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit Tyosinase_C PF18132.1 KEZ44293.1 - 4.1e-26 92.0 0.0 8.6e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Tyosinase C-terminal domain RNA_pol_Rpa2_4 PF06883.12 KEZ44293.1 - 3.5e-21 75.0 0.0 8.8e-21 73.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KEZ44293.1 - 2.4e-18 66.4 0.0 5.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KEZ44293.1 - 4.1e-14 52.7 0.0 3.6e-13 49.7 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Arf PF00025.21 KEZ44294.1 - 2.4e-41 141.1 0.0 2.7e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KEZ44294.1 - 1.4e-18 67.0 0.0 1.5e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ44294.1 - 7.1e-15 55.3 0.0 2.5e-14 53.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KEZ44294.1 - 2.2e-06 27.7 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KEZ44294.1 - 4.5e-06 26.2 0.0 5.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KEZ44294.1 - 1.1e-05 24.9 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KEZ44294.1 - 2.6e-05 23.5 0.0 3.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.27 KEZ44294.1 - 0.0027 17.2 0.0 0.0055 16.3 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 KEZ44294.1 - 0.058 13.4 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 KEZ44294.1 - 0.076 13.1 0.0 1.1 9.3 0.1 2.1 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.18 KEZ44294.1 - 0.11 12.1 0.1 0.43 10.1 0.0 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Beta_elim_lyase PF01212.21 KEZ44295.1 - 5.3e-66 222.9 0.0 6.3e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KEZ44295.1 - 2e-06 27.3 0.0 2.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ44295.1 - 0.0013 17.4 0.0 0.0022 16.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEZ44295.1 - 0.0035 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEZ44295.1 - 0.0082 15.5 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Trehalase PF01204.18 KEZ44296.1 - 2.4e-119 399.5 0.2 2.8e-118 396.0 0.2 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KEZ44296.1 - 0.0075 15.2 0.1 0.014 14.3 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Proteasome PF00227.26 KEZ44297.1 - 7.6e-47 159.3 0.1 9.3e-47 159.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KEZ44297.1 - 1.4e-11 43.6 0.2 1.4e-11 43.6 0.2 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal Sel1 PF08238.12 KEZ44298.1 - 3.5e-11 43.4 6.3 0.0055 17.3 0.1 3.8 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.12 KEZ44299.1 - 4.2e-88 294.9 0.0 8.1e-88 294.0 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KEZ44299.1 - 6.6e-30 103.3 0.1 4.1e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.6 KEZ44300.1 - 3e-32 110.9 2.0 3e-32 110.9 2.0 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KEZ44300.1 - 1.5e-21 76.0 0.0 2.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KEZ44300.1 - 1.3e-09 37.4 0.4 1.3e-09 37.4 0.4 3.7 5 0 0 5 5 5 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KEZ44300.1 - 0.0025 17.9 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 KEZ44301.1 - 1.6e-16 59.9 0.1 1.7e-06 27.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ44301.1 - 0.029 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif U1snRNP70_N PF12220.8 KEZ44301.1 - 0.038 14.6 0.5 0.12 13.1 0.5 1.8 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal GTP-bdg_M PF16360.5 KEZ44301.1 - 0.045 14.3 0.1 0.11 13.2 0.1 1.6 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region Proteasom_Rpn13 PF04683.13 KEZ44302.1 - 4.2e-25 88.1 0.0 6.7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KEZ44302.1 - 1.1e-10 41.6 0.2 1.5e-09 38.0 0.2 2.2 1 1 0 1 1 1 1 UCH-binding domain L27_2 PF09045.10 KEZ44302.1 - 0.017 15.1 0.2 0.035 14.1 0.2 1.4 1 0 0 1 1 1 0 L27_2 EF1_GNE PF00736.19 KEZ44303.1 - 1.3e-33 115.0 0.7 2.4e-33 114.2 0.7 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KEZ44303.1 - 1.4e-14 54.2 7.1 1.4e-14 54.2 7.1 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KEZ44303.1 - 0.0005 20.2 0.4 0.0019 18.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEZ44303.1 - 0.0049 17.1 0.1 0.0049 17.1 0.1 2.5 3 2 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KEZ44303.1 - 0.049 13.7 0.3 0.29 11.2 0.3 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Nucleo_P87 PF07267.11 KEZ44303.1 - 0.18 10.6 1.3 0.73 8.6 0.4 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol3_a_NII PF11490.8 KEZ44303.1 - 0.43 10.5 7.3 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Sld5 PF05916.11 KEZ44304.1 - 6.2e-11 42.7 0.0 8.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Sulfate_transp PF00916.20 KEZ44305.1 - 2.9e-48 164.5 3.4 4.6e-48 163.9 3.4 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KEZ44305.1 - 9.2e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KEZ44305.1 - 5.8e-10 38.8 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain PIRT PF15099.6 KEZ44305.1 - 0.069 12.7 0.2 0.18 11.4 0.2 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Kinesin PF00225.23 KEZ44306.1 - 2.6e-95 319.1 0.0 2.6e-95 319.1 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ44306.1 - 2.3e-23 82.8 0.0 1.7e-21 76.7 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KEZ44306.1 - 1.2 9.0 17.2 0.093 12.6 1.0 4.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TFB6 PF17110.5 KEZ44306.1 - 2.6 7.8 5.0 6.9 6.4 5.0 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Vezatin PF12632.7 KEZ44307.1 - 3.1e-75 253.1 0.4 5e-75 252.4 0.0 1.5 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes Vma12 PF11712.8 KEZ44307.1 - 0.021 14.9 0.2 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase REV PF00424.18 KEZ44307.1 - 6.9 6.8 7.8 0.64 10.1 0.4 2.7 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Rab5ip PF07019.12 KEZ44308.1 - 2.7e-27 95.2 9.8 3.2e-27 94.9 9.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_12 PF13424.6 KEZ44310.1 - 3.5e-19 68.8 6.6 3.9e-07 30.3 1.2 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat Patatin PF01734.22 KEZ44310.1 - 4.9e-11 43.2 0.0 3.2e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.6 KEZ44310.1 - 3e-07 30.1 7.2 0.00077 19.2 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ44310.1 - 4.3e-06 26.5 0.1 0.0035 17.4 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ44310.1 - 5.7e-06 26.0 0.1 0.028 14.4 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ44310.1 - 1.2e-05 25.7 4.3 0.15 12.6 0.3 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ44310.1 - 5.9e-05 22.9 5.9 0.0022 18.0 0.4 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ44310.1 - 6.1e-05 23.4 2.3 0.29 11.8 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ44310.1 - 7.7e-05 22.3 0.2 0.0021 17.8 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ44310.1 - 0.00038 20.8 4.5 0.47 11.2 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ44310.1 - 0.0016 19.1 4.2 3.4 8.7 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ44310.1 - 0.0023 18.1 0.2 0.71 10.1 0.2 3.5 2 2 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KEZ44310.1 - 0.059 14.0 0.2 3.6 8.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEZ44310.1 - 0.14 12.5 0.5 13 6.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Beach PF02138.18 KEZ44310.1 - 0.16 11.3 0.3 0.29 10.5 0.3 1.3 1 0 0 1 1 1 0 Beige/BEACH domain COG4 PF08318.12 KEZ44311.1 - 5.7e-124 413.6 0.0 8.1e-124 413.0 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Clr5 PF14420.6 KEZ44312.1 - 2.8e-05 24.3 0.8 5.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Clr5 domain DUF4110 PF13422.6 KEZ44312.1 - 0.028 14.5 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) MMR_HSR1 PF01926.23 KEZ44313.1 - 3.2e-06 27.2 0.0 1.1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ44313.1 - 0.00047 20.1 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 KEZ44313.1 - 0.0029 17.4 0.1 0.0062 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ44313.1 - 0.0039 17.4 0.3 0.014 15.7 0.2 1.9 2 1 0 2 2 1 1 AAA domain AIG1 PF04548.16 KEZ44313.1 - 0.0044 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 KEZ44313.1 - 0.017 15.6 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KEZ44313.1 - 0.018 15.4 0.2 0.041 14.3 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KEZ44313.1 - 0.031 13.8 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KEZ44313.1 - 0.031 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KEZ44313.1 - 0.034 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PIF1 PF05970.14 KEZ44313.1 - 0.052 12.7 0.1 0.083 12.0 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_29 PF13555.6 KEZ44313.1 - 0.061 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 KEZ44313.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B PhoH PF02562.16 KEZ44313.1 - 0.12 11.8 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 PhoH-like protein MCM PF00493.23 KEZ44313.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain PduV-EutP PF10662.9 KEZ44313.1 - 0.15 11.8 0.0 0.36 10.6 0.1 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KEZ44313.1 - 0.16 11.9 0.4 0.7 9.8 0.3 2.0 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 KEZ44313.1 - 0.17 10.9 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KEZ44313.1 - 0.17 11.0 0.2 0.27 10.4 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.18 KEZ44313.1 - 0.22 10.7 0.2 0.43 9.8 0.2 1.4 1 1 0 1 1 1 0 Septin Cation_ATPase_C PF00689.21 KEZ44314.1 - 4.4e-43 147.1 0.9 7.8e-43 146.3 0.9 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEZ44314.1 - 3.8e-36 124.3 0.4 3.8e-36 124.3 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KEZ44314.1 - 3.4e-19 68.3 0.0 6.8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 KEZ44314.1 - 9.6e-17 62.0 0.2 2.1e-15 57.6 0.1 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ44314.1 - 3.2e-12 46.4 0.0 6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KEZ44314.1 - 5.1e-05 23.1 0.7 5.1e-05 23.1 0.7 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ44314.1 - 0.065 13.6 0.2 0.45 10.9 0.1 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 KEZ44315.1 - 4.1e-37 126.7 0.0 8.8e-37 125.7 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KEZ44315.1 - 5.6e-08 31.9 0.7 9.7e-08 31.2 0.0 1.7 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein Gln-synt_N_2 PF16952.5 KEZ44315.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain TBCA PF02970.16 KEZ44316.1 - 1e-19 70.6 4.7 1.3e-19 70.3 4.7 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Golgin_A5 PF09787.9 KEZ44316.1 - 0.0083 15.6 3.9 0.0096 15.4 3.9 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 CLP1_N PF16573.5 KEZ44316.1 - 0.059 13.6 0.2 0.083 13.1 0.2 1.2 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor SPT16 PF08644.11 KEZ44317.1 - 0.049 13.8 0.1 0.087 13.0 0.1 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Sel1 PF08238.12 KEZ44318.1 - 3.4e-15 56.1 0.1 0.00016 22.2 0.1 3.7 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 KEZ44318.1 - 0.038 14.6 0.1 21 6.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Mob1_phocein PF03637.17 KEZ44319.1 - 1.4e-42 145.6 0.5 3.1e-42 144.5 0.5 1.5 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 KEZ44320.1 - 7.7e-31 107.2 0.1 7.7e-31 107.2 0.1 2.0 2 0 0 2 2 2 1 Leo1-like protein DUF3336 PF11815.8 KEZ44321.1 - 1.4e-37 128.5 0.3 1.3e-36 125.3 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KEZ44321.1 - 5.1e-13 49.7 0.1 1.2e-12 48.4 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Lipase_GDSL_2 PF13472.6 KEZ44322.1 - 1.7e-22 80.7 1.0 2.6e-22 80.1 1.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ44322.1 - 3.7e-12 46.7 0.0 6.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase POTRA PF07244.15 KEZ44322.1 - 0.046 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Surface antigen variable number repeat VWA_3 PF13768.6 KEZ44322.1 - 0.098 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A domain BOP1NT PF08145.12 KEZ44323.1 - 2.3e-99 332.5 10.0 3.2e-99 332.1 10.0 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KEZ44323.1 - 2.7e-14 53.3 5.9 5.1e-09 36.6 0.9 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ44323.1 - 0.00033 20.9 0.0 0.39 11.0 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 KEZ44324.1 - 9.9e-67 220.9 0.4 6.1e-21 74.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IU_nuc_hydro PF01156.19 KEZ44325.1 - 1.1e-71 241.9 0.0 1.9e-71 241.1 0.0 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KEZ44325.1 - 3.5e-05 23.5 12.2 3.5e-05 23.5 12.2 2.5 2 1 0 2 2 2 1 RED-like protein N-terminal region DUF2924 PF11149.8 KEZ44325.1 - 0.088 13.2 3.4 0.85 10.0 3.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) DUF5643 PF18705.1 KEZ44325.1 - 0.8 9.7 4.8 2 8.4 2.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5643) Lsm_interact PF05391.11 KEZ44325.1 - 3.7 7.2 6.7 0.31 10.6 0.9 2.3 2 0 0 2 2 2 0 Lsm interaction motif IMS PF00817.20 KEZ44326.1 - 1.3e-40 138.8 0.0 3.2e-40 137.5 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 KEZ44326.1 - 7.4e-25 87.2 0.6 1.9e-24 85.8 0.6 1.8 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 KEZ44326.1 - 1.3e-15 56.3 15.0 1.2e-07 30.9 3.2 3.8 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 KEZ44326.1 - 1.6e-13 51.4 0.0 4.4e-13 50.0 0.0 1.8 2 0 0 2 2 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KEZ44326.1 - 2.3e-05 24.7 0.0 0.00013 22.3 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain mCpol PF18182.1 KEZ44326.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 KEZ44326.1 - 0.0043 17.3 0.5 0.024 15.0 0.1 2.5 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 KEZ44326.1 - 0.012 15.9 0.2 0.026 14.8 0.0 1.7 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain HHH_5 PF14520.6 KEZ44326.1 - 0.036 14.7 0.0 0.088 13.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1805 PF08827.11 KEZ44326.1 - 0.043 14.2 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) PTCB-BRCT PF12738.7 KEZ44326.1 - 0.055 13.4 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain BRCT PF00533.26 KEZ44326.1 - 0.083 13.3 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.22 KEZ44328.1 - 5.8e-17 61.3 0.0 9.5e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KEZ44328.1 - 1e-05 26.0 8.7 1e-05 26.0 8.7 3.6 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Anp1 PF03452.14 KEZ44329.1 - 1.8e-103 345.6 0.0 2.1e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 UQ_con PF00179.26 KEZ44330.1 - 1.2e-33 115.7 0.0 1.5e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cgr1 PF03879.14 KEZ44331.1 - 4.9e-35 120.2 28.2 5.6e-35 120.0 28.2 1.0 1 0 0 1 1 1 1 Cgr1 family STAT_bind PF02864.15 KEZ44331.1 - 1.2 9.7 5.3 1.6 9.3 5.3 1.2 1 0 0 1 1 1 0 STAT protein, DNA binding domain Fib_alpha PF08702.10 KEZ44332.1 - 0.0062 16.7 5.5 0.017 15.3 5.4 1.7 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF812 PF05667.11 KEZ44332.1 - 0.018 13.9 5.2 0.025 13.5 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Prominin PF05478.11 KEZ44332.1 - 0.021 12.8 0.1 0.061 11.3 0.1 1.6 1 1 0 1 1 1 0 Prominin DUF4208 PF13907.6 KEZ44332.1 - 0.064 13.7 4.0 0.3 11.5 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Occludin_ELL PF07303.13 KEZ44332.1 - 0.11 13.3 3.6 0.13 13.0 1.5 2.2 1 1 0 1 1 1 0 Occludin homology domain SLATT_fungal PF18142.1 KEZ44332.1 - 0.11 12.5 0.9 30 4.6 0.7 2.9 2 1 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Bacillus_HBL PF05791.11 KEZ44332.1 - 0.12 12.1 4.6 0.2 11.4 4.6 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) MCPsignal PF00015.21 KEZ44332.1 - 0.13 12.1 1.4 0.46 10.3 0.2 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3782 PF12644.7 KEZ44332.1 - 0.38 10.9 3.1 6 7.1 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) GAS PF13851.6 KEZ44332.1 - 1 8.7 9.2 0.15 11.4 3.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 KEZ44332.1 - 1.6 8.8 4.5 28 4.7 3.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KEZ44332.1 - 1.8 8.6 4.9 3.1 7.8 0.9 2.2 1 1 2 3 3 3 0 Laminin Domain II DUF16 PF01519.16 KEZ44332.1 - 1.8 9.1 9.7 0.44 11.1 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 MIP-T3_C PF17749.1 KEZ44332.1 - 2.1 8.3 8.7 1.5 8.7 2.3 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region FlaC_arch PF05377.11 KEZ44332.1 - 2.4 8.6 5.7 12 6.4 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Med9 PF07544.13 KEZ44332.1 - 3.3 7.8 7.0 1.1 9.4 1.1 2.7 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 KEZ44332.1 - 6.2 7.2 6.3 14 6.0 0.6 3.4 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3818 PF12825.7 KEZ44333.1 - 2.2e-126 421.5 9.1 3e-126 421.0 7.2 2.0 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KEZ44333.1 - 2.8e-38 130.8 0.8 5.5e-38 129.9 0.8 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KEZ44333.1 - 3.1e-14 52.9 5.9 4.5e-14 52.4 0.4 3.6 3 1 0 3 3 3 1 PX domain FAD_binding_2 PF00890.24 KEZ44334.1 - 8.3e-123 410.5 0.8 1e-122 410.2 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KEZ44334.1 - 3.5e-44 149.9 0.2 5.2e-44 149.3 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 KEZ44334.1 - 0.00011 21.5 0.0 0.27 10.4 0.0 2.9 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.14 KEZ44334.1 - 0.00038 19.8 1.2 0.016 14.5 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ44334.1 - 0.00042 19.5 1.2 0.053 12.6 2.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KEZ44334.1 - 0.011 15.0 0.2 0.021 14.0 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KEZ44334.1 - 0.018 14.6 0.2 0.036 13.7 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ44334.1 - 0.16 10.7 0.9 0.53 8.9 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein zf-GRF PF06839.12 KEZ44335.1 - 6.3e-07 29.4 8.3 1.2e-06 28.5 8.3 1.4 1 0 0 1 1 1 1 GRF zinc finger MerR-DNA-bind PF09278.11 KEZ44335.1 - 0.56 10.8 2.9 4 8.0 2.9 2.3 1 1 0 1 1 1 0 MerR, DNA binding MscS_porin PF12795.7 KEZ44335.1 - 1.8 8.0 7.1 0.09 12.3 0.6 1.9 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain bZIP_2 PF07716.15 KEZ44335.1 - 2.1 8.5 4.4 0.74 9.9 1.1 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Flg_hook PF02120.16 KEZ44336.1 - 0.00014 21.7 0.3 0.074 12.9 0.0 2.7 2 0 0 2 2 2 2 Flagellar hook-length control protein FliK Oxysterol_BP PF01237.18 KEZ44337.1 - 1.7e-87 293.7 0.0 4.5e-85 285.7 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.24 KEZ44338.1 - 1.3e-08 34.5 18.6 5.3e-07 29.4 2.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KEZ44338.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KEZ44338.1 - 0.0036 18.0 1.8 0.4 11.4 0.2 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KEZ44338.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 KEZ44338.1 - 0.049 13.8 1.8 0.39 11.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family SCRG1 PF15224.6 KEZ44338.1 - 0.49 10.5 0.1 0.49 10.5 0.1 2.5 2 1 0 2 2 2 0 Scrapie-responsive protein 1 HET PF06985.11 KEZ44339.1 - 9.1e-29 100.7 0.1 2.1e-28 99.5 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 KEZ44340.1 - 3.4e-20 72.9 0.0 9e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HEAT_2 PF13646.6 KEZ44341.1 - 0.028 14.8 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.22 KEZ44341.1 - 0.028 14.7 0.0 0.25 11.7 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat AAA_9 PF12781.7 KEZ44341.1 - 0.12 11.5 0.1 10 5.2 0.0 2.1 2 0 0 2 2 2 0 ATP-binding dynein motor region CAP_GLY PF01302.25 KEZ44342.1 - 1.2e-15 57.2 0.2 4.1e-15 55.5 0.1 2.0 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KEZ44342.1 - 4.7e-08 32.7 11.7 0.00019 21.2 1.6 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle YscO PF07321.12 KEZ44342.1 - 0.00053 20.0 5.6 0.00053 20.0 5.6 3.3 3 1 0 3 3 3 1 Type III secretion protein YscO Med4 PF10018.9 KEZ44342.1 - 0.025 14.2 0.5 0.025 14.2 0.5 2.8 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 AAA_13 PF13166.6 KEZ44342.1 - 0.048 12.3 14.7 0.064 11.9 11.4 2.3 2 1 0 2 2 2 0 AAA domain RACo_linker PF17650.1 KEZ44342.1 - 0.11 12.4 2.8 0.62 10.0 0.1 2.7 2 0 0 2 2 2 0 RACo linker region NPV_P10 PF05531.12 KEZ44342.1 - 0.15 12.5 8.7 2.1 8.9 0.9 3.3 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Med10 PF09748.9 KEZ44342.1 - 0.18 11.8 0.8 0.45 10.5 0.1 2.0 2 0 0 2 2 1 0 Transcription factor subunit Med10 of Mediator complex Glutaredoxin2_C PF04399.13 KEZ44342.1 - 0.24 11.2 4.3 3 7.7 0.3 2.9 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Spc7 PF08317.11 KEZ44342.1 - 1.1 8.1 31.7 0.47 9.3 1.1 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein APG6_N PF17675.1 KEZ44342.1 - 1.5 9.4 35.8 1.8 9.1 7.2 3.8 3 1 0 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 KEZ44342.1 - 1.6 8.8 11.8 0.53 10.3 1.4 3.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KEZ44342.1 - 1.7 9.0 13.2 0.67 10.3 1.5 3.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 KEZ44342.1 - 2.2 8.6 4.5 1.4 9.2 0.7 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.11 KEZ44342.1 - 3.2 7.6 18.3 1.7 8.5 0.2 3.7 3 1 0 3 3 3 0 Phage minor structural protein GP20 EzrA PF06160.12 KEZ44342.1 - 3.6 5.6 15.9 0.15 10.2 5.0 2.8 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA FliD_N PF02465.18 KEZ44342.1 - 4.1 8.2 7.2 6 7.6 1.1 3.5 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4239 PF14023.6 KEZ44342.1 - 7.1 6.3 5.4 19 4.9 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4239) Pkinase PF00069.25 KEZ44343.1 - 2.2e-34 119.1 0.0 6.3e-20 71.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44343.1 - 6.9e-14 51.7 0.0 7.4e-10 38.5 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEZ44343.1 - 0.00084 18.7 0.0 0.33 10.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KEZ44343.1 - 0.0061 16.5 0.0 0.051 13.5 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_38N PF01074.22 KEZ44344.1 - 7.6e-88 294.6 1.0 1.4e-87 293.8 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KEZ44344.1 - 6.8e-54 183.2 0.1 2e-53 181.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KEZ44344.1 - 3.3e-29 100.9 0.0 9.9e-29 99.4 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KEZ44344.1 - 2.6e-13 49.9 0.1 1.8e-12 47.2 0.1 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KEZ44344.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SNARE_assoc PF09335.11 KEZ44345.1 - 2.6e-13 50.5 6.5 2.6e-13 50.5 6.5 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Hrs_helical PF12210.8 KEZ44346.1 - 0.0039 17.7 1.6 0.12 13.0 0.5 2.4 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Herpes_UL6 PF01763.16 KEZ44346.1 - 0.17 10.3 0.1 0.25 9.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Abhydrolase_1 PF00561.20 KEZ44347.1 - 1.9e-13 50.6 0.0 6.9e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ44347.1 - 1.6e-07 32.2 0.4 8.4e-05 23.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ44347.1 - 3.8e-06 26.4 0.0 1.1e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 KEZ44347.1 - 0.17 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DEAD PF00270.29 KEZ44348.1 - 5.8e-13 49.0 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ44348.1 - 0.00015 22.1 0.0 0.00061 20.1 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ44348.1 - 0.0017 18.4 0.0 0.012 15.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 KEZ44348.1 - 0.051 14.2 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain PHD PF00628.29 KEZ44349.1 - 3.8e-15 55.5 35.3 1.1e-08 34.8 4.4 5.3 5 0 0 5 5 5 2 PHD-finger PHD_2 PF13831.6 KEZ44349.1 - 1.8e-09 37.0 2.4 1.8e-09 37.0 2.4 4.5 5 0 0 5 5 5 2 PHD-finger zf-HC5HC2H_2 PF13832.6 KEZ44349.1 - 2.5e-05 24.4 15.4 0.00013 22.1 0.2 4.5 3 1 1 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 KEZ44349.1 - 0.00045 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain Myb_DNA-binding PF00249.31 KEZ44349.1 - 0.00051 20.2 1.3 0.0008 19.6 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Prok-RING_1 PF14446.6 KEZ44349.1 - 0.0048 16.8 0.7 0.0048 16.8 0.7 3.8 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 C1_1 PF00130.22 KEZ44349.1 - 0.014 15.3 0.8 0.014 15.3 0.8 5.3 4 2 2 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HBS1_N PF08938.10 KEZ44349.1 - 0.039 14.3 1.5 0.16 12.3 0.0 2.8 2 0 0 2 2 2 0 HBS1 N-terminus TrkA_C PF02080.21 KEZ44349.1 - 0.22 11.4 0.0 0.48 10.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain DnaJ_C PF01556.18 KEZ44350.1 - 1e-37 129.5 0.1 1.3e-37 129.2 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ44350.1 - 6.3e-26 90.3 3.5 6.7e-26 90.2 2.0 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEZ44350.1 - 1.1e-16 60.9 17.9 2e-16 60.1 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEZ44350.1 - 0.011 15.6 16.1 0.09 12.7 2.8 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_9 PF14369.6 KEZ44350.1 - 0.15 12.3 2.4 22 5.4 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon HypA PF01155.19 KEZ44350.1 - 0.35 10.9 9.7 0.56 10.2 2.4 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 KEZ44350.1 - 0.37 10.8 7.8 5.6 7.0 2.7 2.4 1 1 1 2 2 2 0 zinc-ribbons DUF2614 PF11023.8 KEZ44350.1 - 3.7 7.7 6.7 4.1 7.5 1.1 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain CPSF_A PF03178.15 KEZ44351.1 - 0.0021 17.4 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region WD40 PF00400.32 KEZ44351.1 - 0.028 15.3 0.8 7.6 7.6 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat TSA PF03249.13 KEZ44351.1 - 0.24 10.2 0.0 0.24 10.2 0.0 2.0 2 0 0 2 2 2 0 Type specific antigen Ribosomal_L10 PF00466.20 KEZ44352.1 - 2.8e-23 81.9 0.0 6.3e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KEZ44352.1 - 4.9e-22 77.7 0.0 8.8e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KEZ44352.1 - 8.8e-19 67.9 7.2 2.1e-18 66.7 5.5 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.21 KEZ44353.1 - 5.2e-67 225.5 0.9 8.7e-66 221.5 0.9 2.5 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KEZ44353.1 - 9.1e-50 169.5 5.2 1.7e-49 168.7 5.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KEZ44353.1 - 2.4e-18 66.4 0.0 5.6e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KEZ44353.1 - 2.4e-09 37.6 0.0 7.2e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 KEZ44353.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ44353.1 - 0.3 11.6 1.6 0.8 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF1771 PF08590.10 KEZ44354.1 - 4.1e-15 55.9 11.6 8.5e-15 54.9 11.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KEZ44354.1 - 3.7e-08 33.6 0.0 9.1e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 KEZ44354.1 - 1e-07 31.8 8.9 8.7e-06 25.6 0.9 3.0 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KEZ44354.1 - 1.5e-07 31.2 4.0 0.0017 18.2 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KEZ44354.1 - 0.0001 22.6 4.5 0.2 12.2 0.5 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KEZ44354.1 - 0.00025 20.8 11.1 0.00033 20.4 0.7 3.0 2 1 0 2 2 2 1 CCCH-type zinc finger HBS1_N PF08938.10 KEZ44354.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 HBS1 N-terminus zf-CCCH_3 PF15663.5 KEZ44354.1 - 0.03 14.5 1.9 1.5 9.0 0.1 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 KEZ44354.1 - 1.5 9.5 5.1 1.5 9.5 0.8 2.3 1 1 1 2 2 2 0 Torus domain MFS_1 PF07690.16 KEZ44355.1 - 3.6e-13 49.2 22.3 2.4e-09 36.6 3.4 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ44355.1 - 0.36 9.2 6.7 0.59 8.5 0.2 2.4 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) UDPGT PF00201.18 KEZ44356.1 - 1e-18 67.4 0.0 2.2e-18 66.4 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEZ44356.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Cupin_8 PF13621.6 KEZ44357.1 - 2.4e-18 66.8 0.1 3.5e-16 59.7 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KEZ44357.1 - 5e-10 39.8 0.0 1.3e-09 38.4 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KEZ44357.1 - 0.00045 20.0 0.0 0.00096 19.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like ScsC_N PF18312.1 KEZ44357.1 - 0.015 15.1 0.4 0.028 14.2 0.4 1.4 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain F-box PF00646.33 KEZ44357.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 F-box domain DEAD PF00270.29 KEZ44358.1 - 1.6e-45 155.0 1.5 2.6e-45 154.4 1.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ44358.1 - 2.9e-32 111.3 0.3 8.7e-31 106.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ44358.1 - 1.4e-06 28.4 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KEZ44358.1 - 7.9e-05 22.4 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ44358.1 - 0.00065 20.1 1.6 0.0031 17.8 0.7 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 KEZ44358.1 - 0.019 15.0 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 KEZ44358.1 - 0.021 15.1 0.7 0.12 12.7 0.7 2.2 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KEZ44358.1 - 0.046 13.1 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 KEZ44358.1 - 0.048 13.5 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 KEZ44358.1 - 0.052 13.5 0.2 0.24 11.3 0.2 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 KEZ44358.1 - 0.074 12.6 0.3 0.11 12.0 0.3 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain tRNA-synt_1b PF00579.25 KEZ44358.1 - 0.084 12.2 0.2 0.51 9.6 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) DASH_Ask1 PF08655.10 KEZ44358.1 - 0.1 12.5 0.2 0.59 10.1 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Ask1 fragilysinNterm PF16376.5 KEZ44358.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin Clat_adaptor_s PF01217.20 KEZ44359.1 - 7.7e-18 64.8 0.2 2.2e-15 56.8 0.6 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain MCM PF00493.23 KEZ44360.1 - 2.4e-101 337.5 0.0 3.6e-101 337.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEZ44360.1 - 4.7e-39 133.1 1.3 8.3e-39 132.3 1.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEZ44360.1 - 7.1e-29 100.1 3.3 1.6e-28 99.0 3.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEZ44360.1 - 1.1e-16 61.3 0.0 4e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEZ44360.1 - 1.7e-05 24.3 0.0 0.00082 18.8 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEZ44360.1 - 3.9e-05 23.7 0.1 0.00021 21.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KEZ44360.1 - 0.00061 19.6 0.0 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RcpC PF16976.5 KEZ44360.1 - 0.017 15.2 0.2 0.043 13.9 0.2 1.6 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB Oberon_cc PF16312.5 KEZ44360.1 - 0.32 10.9 3.2 0.7 9.8 3.2 1.5 1 0 0 1 1 1 0 Coiled-coil region of Oberon Cys_Met_Meta_PP PF01053.20 KEZ44361.1 - 4.2e-18 65.0 0.0 4.4e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme VTC PF09359.10 KEZ44362.1 - 3.5e-95 318.5 0.0 5.3e-95 317.9 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 KEZ44362.1 - 1e-14 55.3 8.9 7.8e-06 26.1 0.1 4.0 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 KEZ44362.1 - 1.2e-11 44.8 0.7 1.2e-11 44.8 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ank_2 PF12796.7 KEZ44363.1 - 0.043 14.4 0.0 0.84 10.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Hexokinase_2 PF03727.16 KEZ44364.1 - 9.7e-79 264.2 0.0 1.4e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KEZ44364.1 - 1.5e-72 243.7 0.0 2.6e-72 242.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Ribophorin_I PF04597.14 KEZ44365.1 - 9.8e-149 496.3 0.5 1.1e-148 496.1 0.5 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.6 KEZ44367.1 - 9.6e-109 362.9 5.4 1.2e-108 362.6 5.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 WW PF00397.26 KEZ44368.1 - 1.7e-11 44.0 0.1 4.1e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KEZ44368.1 - 0.034 13.2 0.4 0.064 12.3 0.4 1.5 1 1 0 1 1 1 0 PhoD-like phosphatase PMM PF03332.13 KEZ44369.1 - 3.7e-100 334.2 0.0 4.3e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KEZ44369.1 - 0.0067 16.2 0.0 0.1 12.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Na_Ca_ex PF01699.24 KEZ44370.1 - 4.1e-46 156.7 35.5 5.1e-30 104.4 15.9 3.1 3 1 1 4 4 4 2 Sodium/calcium exchanger protein Cnd2 PF05786.14 KEZ44371.1 - 0 1061.7 0.4 0 1061.5 0.4 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KEZ44371.1 - 0.0025 18.0 0.1 0.0065 16.7 0.1 1.7 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal HMG_box PF00505.19 KEZ44372.1 - 5.1e-14 52.4 0.4 5.1e-14 52.4 0.4 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.30 KEZ44372.1 - 1.8e-10 41.1 2.2 4.4e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 KEZ44372.1 - 6.1e-10 39.6 0.3 6.1e-10 39.6 0.3 2.1 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.17 KEZ44372.1 - 6.8e-06 26.1 0.6 1.2e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF5613 PF18467.1 KEZ44372.1 - 0.0068 16.8 1.7 0.012 16.0 1.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5613) WYL_3 PF18488.1 KEZ44372.1 - 0.086 13.2 4.0 0.17 12.3 4.0 1.5 1 0 0 1 1 1 0 WYL domain HTH_Tnp_ISL3 PF13542.6 KEZ44372.1 - 0.14 11.6 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 4HB_MCP_1 PF12729.7 KEZ44372.1 - 0.36 10.3 3.7 0.56 9.7 3.7 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF883 PF05957.13 KEZ44372.1 - 1.6 9.4 4.1 1.5 9.5 0.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CCDC53 PF10152.9 KEZ44373.1 - 0.042 14.3 0.5 0.042 14.3 0.5 1.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HAMP PF00672.25 KEZ44374.1 - 7.1e-40 135.2 12.1 7e-08 32.7 0.2 7.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KEZ44374.1 - 1.1e-30 106.4 0.2 3.5e-30 104.8 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ44374.1 - 8.9e-27 93.5 0.6 9.6e-26 90.1 0.2 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KEZ44374.1 - 1.7e-17 63.2 4.1 3.1e-17 62.4 0.7 3.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KEZ44374.1 - 0.00027 21.2 18.2 4.1 7.8 0.3 7.4 3 1 3 7 7 6 1 Syntaxin-like protein Fib_alpha PF08702.10 KEZ44374.1 - 0.0011 19.1 28.6 0.084 13.1 0.3 6.8 7 1 0 7 7 6 2 Fibrinogen alpha/beta chain family DUF3829 PF12889.7 KEZ44374.1 - 0.014 14.8 13.2 1.6 8.2 0.2 4.8 4 2 0 5 5 5 0 Protein of unknown function (DUF3829) Gp-FAR-1 PF05823.12 KEZ44374.1 - 0.015 15.6 0.2 25 5.2 0.1 4.4 2 2 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1759 PF03564.15 KEZ44374.1 - 0.081 12.9 0.6 23 4.9 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) DUF948 PF06103.11 KEZ44374.1 - 0.34 11.2 52.0 0.59 10.4 1.5 9.6 4 2 4 8 8 8 0 Bacterial protein of unknown function (DUF948) DUF4795 PF16043.5 KEZ44374.1 - 0.35 10.4 23.3 4 7.0 3.7 4.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SpoIIID PF12116.8 KEZ44374.1 - 0.35 11.0 5.2 83 3.4 0.1 5.2 4 1 1 5 5 5 0 Stage III sporulation protein D GhoS PF11080.8 KEZ44374.1 - 0.47 10.5 5.3 1.6 8.7 0.0 3.8 4 0 0 4 4 4 0 Endoribonuclease GhoS BORCS8 PF10167.9 KEZ44374.1 - 0.57 10.1 4.7 4 7.4 0.1 3.8 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 AdHead_fibreRBD PF16812.5 KEZ44374.1 - 1.3 8.8 6.8 0.81 9.5 0.1 3.1 3 0 0 3 3 3 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Syntaphilin PF15290.6 KEZ44374.1 - 2.4 7.7 7.5 3.2 7.3 0.3 3.3 3 0 0 3 3 3 0 Golgi-localised syntaxin-1-binding clamp AAA_13 PF13166.6 KEZ44374.1 - 4.5 5.8 23.4 1.1 7.8 6.1 3.1 2 1 1 3 3 3 0 AAA domain WXG100 PF06013.12 KEZ44374.1 - 6.1 7.2 26.0 15 5.9 0.2 7.4 4 2 1 7 7 7 0 Proteins of 100 residues with WXG C2 PF00168.30 KEZ44375.1 - 6.7e-17 61.7 0.0 1.6e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 KEZ44375.1 - 5.4e-14 52.6 2.3 4.2e-11 43.2 2.3 2.6 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 KEZ44375.1 - 1.5e-05 23.8 0.3 2.6e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) ArfGap PF01412.18 KEZ44376.1 - 9e-35 119.3 0.0 2.6e-34 117.8 0.0 1.8 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KEZ44376.1 - 2e-21 76.8 10.5 3.1e-21 76.2 10.5 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KEZ44376.1 - 2e-11 44.3 0.1 5.4e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 PH domain EMP24_GP25L PF01105.24 KEZ44376.1 - 0.082 12.8 3.4 0.096 12.6 1.1 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Phage_GP20 PF06810.11 KEZ44376.1 - 1.4 8.7 7.3 2.6 7.8 0.8 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Pkinase PF00069.25 KEZ44377.1 - 1e-77 261.1 0.0 1.4e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44377.1 - 2.5e-39 135.1 0.0 3.5e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEZ44377.1 - 9.1e-14 51.6 0.1 2.1e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KEZ44377.1 - 1.2e-12 47.8 0.0 1.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KEZ44377.1 - 7.4e-07 28.3 0.8 1.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KEZ44377.1 - 0.0014 18.9 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KEZ44377.1 - 0.0036 16.7 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KEZ44377.1 - 0.07 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 KEZ44377.1 - 0.13 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 KEZ44377.1 - 3.7 7.4 5.4 4.8 7.0 0.2 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family PCI PF01399.27 KEZ44378.1 - 5.2e-14 52.6 0.0 2.7e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KEZ44378.1 - 8.4e-12 44.6 2.3 8.4e-12 44.6 2.3 2.2 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix Tox-SHH PF15652.6 KEZ44378.1 - 0.043 14.8 0.2 5.6 8.0 0.1 3.4 3 1 0 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature Hox9_act PF04617.13 KEZ44378.1 - 0.15 12.8 0.0 0.32 11.7 0.0 1.5 1 0 0 1 1 1 0 Hox9 activation region MatP_C PF17414.2 KEZ44378.1 - 0.19 11.9 1.0 0.5 10.6 1.0 1.7 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain ADK PF00406.22 KEZ44379.1 - 4.7e-45 153.4 0.0 6.1e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KEZ44379.1 - 5e-35 120.9 0.0 7.4e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ44379.1 - 4.5e-08 33.7 0.0 6.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEZ44379.1 - 0.00029 21.0 0.2 0.0038 17.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KEZ44379.1 - 0.0077 15.9 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 KEZ44379.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PAS_7 PF12860.7 KEZ44379.1 - 0.13 12.4 0.0 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 PAS fold MARVEL PF01284.23 KEZ44380.1 - 0.008 16.2 9.4 0.009 16.0 7.9 1.8 1 1 0 1 1 1 1 Membrane-associating domain Ninjurin PF04923.12 KEZ44380.1 - 0.021 14.7 1.7 0.048 13.6 0.1 2.1 2 0 0 2 2 2 0 Ninjurin DUF3169 PF11368.8 KEZ44380.1 - 0.033 13.7 4.3 1.1 8.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Peptidase_M56 PF05569.11 KEZ44380.1 - 0.065 12.4 4.3 0.097 11.8 4.3 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3290 PF11694.8 KEZ44380.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF4059 PF13268.6 KEZ44380.1 - 0.35 11.3 7.9 3.2 8.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) DUF2569 PF10754.9 KEZ44380.1 - 0.93 9.9 10.4 0.19 12.2 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) MASE3 PF17159.4 KEZ44380.1 - 1.1 8.9 9.7 0.19 11.3 3.6 2.0 2 0 0 2 2 2 0 Membrane-associated sensor domain ER_lumen_recept PF00810.18 KEZ44380.1 - 3.6 8.4 8.8 2.5 8.9 5.8 2.0 2 1 1 3 3 3 0 ER lumen protein retaining receptor SUR7 PF06687.12 KEZ44380.1 - 8.3 6.0 12.4 0.75 9.4 5.3 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF5102 PF17104.5 KEZ44381.1 - 3.1e-111 372.0 2.0 3.1e-111 372.0 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) eIF2_C PF09173.11 KEZ44382.1 - 6.8e-34 116.0 0.4 1.5e-33 114.8 0.4 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KEZ44382.1 - 8e-23 81.0 1.3 1.1e-21 77.3 1.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KEZ44382.1 - 1.4e-10 41.4 0.2 3e-10 40.3 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KEZ44382.1 - 0.004 17.2 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KEZ44382.1 - 0.0074 16.3 0.9 0.02 14.9 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 KEZ44382.1 - 0.074 13.0 0.2 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase 6PGD PF00393.19 KEZ44383.1 - 1.4e-127 425.0 0.0 1.9e-127 424.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KEZ44383.1 - 5.5e-49 166.4 0.0 8.9e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Nsp1_C PF05064.13 KEZ44384.1 - 3.8e-41 139.5 3.3 8.8e-41 138.4 3.3 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KEZ44384.1 - 1e-14 55.1 156.8 2.4e-05 25.1 33.3 7.4 2 1 4 6 6 6 3 Nucleoporin FG repeat region DUF948 PF06103.11 KEZ44384.1 - 0.091 13.0 1.8 0.46 10.8 1.4 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Peptidase_M24_C PF16188.5 KEZ44384.1 - 0.12 12.4 0.9 0.55 10.3 0.3 2.3 2 1 0 2 2 2 0 C-terminal region of peptidase_M24 ERM PF00769.19 KEZ44384.1 - 0.29 10.9 7.9 0.43 10.4 7.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 KEZ44384.1 - 2 8.5 6.7 1.4 9.0 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 KEZ44384.1 - 5.1 6.9 9.0 2 8.2 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4200 PF13863.6 KEZ44384.1 - 6.9 7.1 11.9 28 5.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IATP PF04568.12 KEZ44385.1 - 1.2e-29 102.6 1.8 1.3e-29 102.5 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HTH_32 PF13565.6 KEZ44385.1 - 0.016 15.8 0.5 0.02 15.5 0.5 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Peptidase_S15 PF02129.18 KEZ44385.1 - 0.084 12.5 0.2 0.085 12.4 0.2 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1003 PF06210.11 KEZ44385.1 - 0.12 12.4 2.9 0.17 12.0 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF2205 PF10224.9 KEZ44385.1 - 0.21 11.6 4.5 0.29 11.2 4.5 1.2 1 0 0 1 1 1 0 Short coiled-coil protein GTP_EFTU_D2 PF03144.25 KEZ44386.1 - 0.18 12.2 0.1 8.7 6.8 0.1 2.9 2 0 0 2 2 2 0 Elongation factor Tu domain 2 HMG_CoA_synt_C PF08540.10 KEZ44388.1 - 8.1e-93 311.1 0.1 1.1e-92 310.7 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KEZ44388.1 - 3.4e-81 271.3 0.1 5.2e-81 270.7 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal 14-3-3 PF00244.20 KEZ44389.1 - 1.5e-106 354.9 3.8 1.7e-106 354.7 3.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 KEZ44389.1 - 1.6 9.3 5.4 0.76 10.3 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Mitoc_mL59 PF18126.1 KEZ44390.1 - 1.1e-44 151.8 3.2 1.4e-44 151.6 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Mito_carr PF00153.27 KEZ44391.1 - 4.4e-60 199.6 0.1 1.2e-20 73.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_6 PF08036.11 KEZ44391.1 - 3 8.0 6.0 7.3 6.7 0.2 3.0 3 0 0 3 3 3 0 Diapausin family of antimicrobial peptide TspO_MBR PF03073.15 KEZ44392.1 - 3.6e-38 130.7 3.0 4.4e-38 130.4 3.0 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.8 KEZ44393.1 - 8.2e-33 112.9 4.1 8.2e-33 112.9 4.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KEZ44393.1 - 7.5e-12 46.0 1.3 1.5e-11 45.1 0.2 2.2 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KEZ44393.1 - 7e-10 38.5 0.6 1.7e-09 37.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Astro_capsid_p PF12226.8 KEZ44393.1 - 0.79 8.8 6.0 1.3 8.1 6.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DAHP_synth_1 PF00793.20 KEZ44394.1 - 6.2e-102 340.2 0.0 9.2e-102 339.6 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family Cytochrom_C1 PF02167.15 KEZ44394.1 - 4.1e-91 304.6 0.0 5.8e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KEZ44394.1 - 0.019 15.3 0.0 0.055 13.8 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AAA PF00004.29 KEZ44395.1 - 3e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ44395.1 - 2.2e-07 30.6 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KEZ44395.1 - 8.2e-05 22.6 0.1 0.00062 19.8 0.0 2.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ44395.1 - 0.00014 22.2 0.0 0.0055 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KEZ44395.1 - 0.00051 20.2 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KEZ44395.1 - 0.00066 20.1 0.1 0.015 15.7 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KEZ44395.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KEZ44395.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KEZ44395.1 - 0.02 15.2 0.1 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ44395.1 - 0.034 13.9 0.1 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ44395.1 - 0.04 13.4 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KEZ44395.1 - 0.044 14.2 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 KEZ44395.1 - 0.049 13.8 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KEZ44395.1 - 0.069 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KEZ44395.1 - 0.1 11.9 0.1 6.9 5.9 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KEZ44395.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KEZ44395.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 KEZ44396.1 - 2e-150 501.7 16.5 2.2e-150 501.5 16.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans_2 PF11951.8 KEZ44397.1 - 7.5e-50 169.8 0.0 1.1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.21 KEZ44398.1 - 4.9e-49 166.6 0.1 2.3e-48 164.4 0.1 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KEZ44398.1 - 1e-11 45.1 0.0 0.00012 22.8 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ44398.1 - 0.00087 19.6 0.0 2.6 8.4 0.0 4.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ44398.1 - 0.075 12.0 1.0 3.9 6.3 0.1 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Indigoidine_A PF04227.12 KEZ44400.1 - 6.4e-108 360.5 0.2 1.1e-107 359.8 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KEZ44400.1 - 2.8e-22 79.4 0.2 1.1e-12 47.9 0.0 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase SLD5_C PF16922.5 KEZ44400.1 - 1.3e-11 44.5 0.8 3e-11 43.3 0.8 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KEZ44400.1 - 1.7e-06 28.5 0.1 4e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 GINS complex protein HSP70 PF00012.20 KEZ44400.1 - 0.0095 14.2 0.4 0.052 11.7 0.1 2.0 2 0 0 2 2 2 1 Hsp70 protein HTH_DeoR PF08220.12 KEZ44400.1 - 0.14 11.9 0.1 0.5 10.1 0.1 1.9 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain UBM PF14377.6 KEZ44400.1 - 0.45 10.0 2.3 0.64 9.5 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin binding region NapD PF03927.13 KEZ44401.1 - 0.11 12.6 0.1 19 5.4 0.0 3.0 3 0 0 3 3 3 0 NapD protein Tnp_22_trimer PF17489.2 KEZ44402.1 - 0.032 14.2 0.2 7 6.7 0.0 2.5 2 0 0 2 2 2 0 L1 transposable element trimerization domain HemX PF04375.14 KEZ44402.1 - 0.037 13.3 1.8 0.055 12.8 1.8 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fmp27_WPPW PF10359.9 KEZ44402.1 - 0.046 12.6 0.3 0.064 12.1 0.3 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tropomyosin PF00261.20 KEZ44402.1 - 0.14 11.5 4.5 0.21 10.9 4.5 1.1 1 0 0 1 1 1 0 Tropomyosin GreA_GreB_N PF03449.15 KEZ44402.1 - 0.19 11.9 2.7 0.83 9.8 0.2 2.4 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal RecQ5 PF06959.11 KEZ44403.1 - 0.22 11.5 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) FAD_binding_3 PF01494.19 KEZ44404.1 - 4.5e-77 259.7 0.0 5.5e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEZ44404.1 - 1.1e-30 106.9 0.0 2e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KEZ44404.1 - 1.6e-08 34.2 0.0 3.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ44404.1 - 3.9e-07 30.5 0.0 0.00024 21.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ44404.1 - 3.7e-06 26.8 0.1 0.0042 16.7 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ44404.1 - 2.1e-05 23.4 0.2 6.1e-05 21.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KEZ44404.1 - 7.2e-05 22.9 0.1 0.00017 21.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ44404.1 - 0.00017 20.8 0.1 0.00027 20.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KEZ44404.1 - 0.0044 16.3 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KEZ44404.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ44404.1 - 0.0072 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 KEZ44404.1 - 0.0085 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KEZ44404.1 - 0.0089 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 KEZ44404.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 KEZ44404.1 - 0.015 14.4 0.1 0.03 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.6 KEZ44404.1 - 0.03 14.8 0.0 0.073 13.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 KEZ44404.1 - 0.038 13.3 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEZ44404.1 - 0.076 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KEZ44404.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KEZ44404.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 KEZ44404.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KEZ44404.1 - 0.2 10.9 0.2 0.41 9.9 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aldedh PF00171.22 KEZ44405.1 - 1.5e-132 442.4 0.6 1.8e-132 442.2 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MgsA_C PF12002.8 KEZ44405.1 - 0.054 13.4 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Bromo_TP PF07524.13 KEZ44406.1 - 3e-10 40.0 0.0 4.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 KEZ44406.1 - 0.0014 18.7 0.1 0.0023 18.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF1746 PF08508.10 KEZ44407.1 - 2.3e-37 127.8 1.0 3.6e-37 127.2 1.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CDC45 PF02724.14 KEZ44407.1 - 1.5 7.0 6.2 0.71 8.1 0.2 2.0 2 0 0 2 2 2 0 CDC45-like protein REV PF00424.18 KEZ44407.1 - 2.7 8.1 17.7 0.73 9.9 0.1 2.7 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Peptidase_A21 PF03566.13 KEZ44407.1 - 9 4.4 9.9 4.6 5.4 2.6 2.1 2 0 0 2 2 2 0 Peptidase family A21 tRNA-synt_2d PF01409.20 KEZ44408.1 - 3.5e-85 285.4 0.0 4.7e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KEZ44408.1 - 2.8e-17 62.7 0.8 8.2e-17 61.2 0.5 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KEZ44408.1 - 4.3e-06 26.3 0.0 0.0031 17.0 0.0 2.7 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 KEZ44408.1 - 4.1e-05 23.5 5.3 0.00011 22.1 5.3 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 KEZ44408.1 - 0.00011 21.5 0.5 0.0025 17.0 0.1 2.7 2 1 1 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KEZ44408.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) NPL4 PF05021.15 KEZ44409.1 - 2e-140 467.5 0.0 2.6e-140 467.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KEZ44409.1 - 3.8e-68 228.2 0.0 6.1e-68 227.5 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KEZ44409.1 - 0.00026 21.4 0.0 0.0017 18.8 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 CPSase_L_D2 PF02786.17 KEZ44410.1 - 2.8e-110 366.8 0.2 4.7e-84 281.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KEZ44410.1 - 2.1e-40 137.8 0.0 6.8e-40 136.2 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KEZ44410.1 - 5e-21 75.0 0.1 9.7e-10 38.3 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEZ44410.1 - 1.2e-17 64.2 1.3 1.2e-07 31.4 0.3 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KEZ44410.1 - 2.6e-11 43.4 0.0 0.00027 20.7 0.0 3.1 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KEZ44410.1 - 1.9e-05 24.7 0.3 0.22 11.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KEZ44410.1 - 3.7e-05 23.3 0.5 0.065 12.7 0.1 2.7 2 1 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 KEZ44410.1 - 8.8e-05 22.4 0.5 0.55 10.0 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KEZ44410.1 - 0.0005 19.7 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.22 KEZ44410.1 - 0.013 15.6 0.0 0.052 13.7 0.0 2.0 1 0 0 1 1 1 0 MGS-like domain Sec66 PF09802.9 KEZ44411.1 - 1.6e-81 272.2 1.1 1.9e-81 271.9 1.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 KEZ44411.1 - 0.029 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Stm1_N PF09598.10 KEZ44411.1 - 0.91 10.4 12.9 2.6 9.0 12.9 1.8 1 1 0 1 1 1 0 Stm1 PepSY_TM PF03929.16 KEZ44411.1 - 1.9 8.1 3.6 8.2 6.0 3.6 2.0 1 1 0 1 1 1 0 PepSY-associated TM region Med3 PF11593.8 KEZ44411.1 - 4.5 6.3 8.8 5.7 6.0 8.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ORC3_N PF07034.11 KEZ44412.1 - 5.6e-32 111.2 7.4 2.6e-30 105.7 1.3 3.2 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KEZ44412.1 - 2.9e-24 85.7 0.0 1.4e-12 47.8 0.0 2.4 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal UPF0158 PF03682.13 KEZ44412.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF2564 PF10819.8 KEZ44412.1 - 0.15 12.5 1.0 14 6.1 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) PWWP PF00855.17 KEZ44413.1 - 9.2e-19 67.7 1.2 7.5e-18 64.7 0.0 3.0 2 0 0 2 2 2 1 PWWP domain Sec63 PF02889.16 KEZ44414.1 - 8e-161 533.1 0.1 3.2e-88 295.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KEZ44414.1 - 5.5e-49 166.3 0.0 1.1e-27 97.0 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KEZ44414.1 - 9e-36 122.4 0.1 3.1e-35 120.7 0.1 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KEZ44414.1 - 1.6e-23 83.6 0.0 1.7e-13 50.9 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KEZ44414.1 - 2.4e-11 44.0 0.0 2.7e-08 34.2 0.0 3.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KEZ44414.1 - 1.5e-07 31.8 0.1 0.0042 17.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KEZ44414.1 - 7.4e-05 21.9 0.0 0.38 9.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein UvrD-helicase PF00580.21 KEZ44414.1 - 0.015 14.8 0.3 3.9 6.9 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KEZ44414.1 - 0.024 15.0 0.0 5.3 7.4 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 KEZ44414.1 - 0.032 13.7 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 KEZ44414.1 - 0.038 13.5 0.0 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 KEZ44414.1 - 0.11 13.0 5.2 41 4.6 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KEZ44414.1 - 0.12 12.7 0.0 17 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KEZ44414.1 - 2.7 7.7 6.9 29 4.3 0.0 3.6 3 1 0 4 4 4 0 AAA domain Rep_fac_C PF08542.11 KEZ44415.1 - 1.2e-21 76.9 0.0 2.3e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KEZ44415.1 - 2.8e-16 60.2 0.0 1.2e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KEZ44415.1 - 1.8e-12 47.3 0.0 4.2e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KEZ44415.1 - 2.2e-09 37.5 0.1 8.1e-09 35.7 0.0 1.9 3 0 0 3 3 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KEZ44415.1 - 6.9e-06 25.9 0.0 2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KEZ44415.1 - 1.9e-05 24.6 0.0 4.3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ44415.1 - 2.5e-05 24.7 0.1 0.0012 19.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEZ44415.1 - 4.1e-05 23.9 0.0 0.0035 17.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KEZ44415.1 - 9.8e-05 22.6 0.0 0.00029 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 KEZ44415.1 - 0.00017 21.1 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KEZ44415.1 - 0.00086 19.4 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 KEZ44415.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 KEZ44415.1 - 0.0016 18.8 0.0 0.012 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KEZ44415.1 - 0.0031 17.3 0.0 0.0068 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEZ44415.1 - 0.0045 16.5 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KEZ44415.1 - 0.0069 16.6 0.0 0.045 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEZ44415.1 - 0.0094 16.0 0.1 0.08 12.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KEZ44415.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 KEZ44415.1 - 0.016 15.0 0.0 0.096 12.4 0.0 2.3 3 1 0 3 3 3 0 AAA domain ResIII PF04851.15 KEZ44415.1 - 0.038 14.0 0.0 0.22 11.5 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 KEZ44415.1 - 0.04 14.5 0.0 0.12 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ44415.1 - 0.055 12.7 0.0 0.18 11.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 KEZ44415.1 - 0.06 13.2 0.0 0.31 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KEZ44415.1 - 0.071 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KEZ44415.1 - 0.12 12.2 0.2 1.7 8.4 0.0 2.5 2 1 0 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KEZ44415.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase UQ_con PF00179.26 KEZ44416.1 - 9.3e-45 151.7 0.0 2.5e-30 105.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ44416.1 - 0.00031 20.5 0.0 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic E2 family B UEV PF05743.13 KEZ44416.1 - 0.029 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 UEV domain FDC-SP PF15215.6 KEZ44416.1 - 0.09 13.3 0.1 0.64 10.6 0.0 2.2 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide Transglut_N PF00868.20 KEZ44416.1 - 0.12 12.7 0.0 6.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Transglutaminase family CHORD PF04968.12 KEZ44417.1 - 1.6e-25 89.6 5.2 1.6e-25 89.6 5.2 2.0 2 0 0 2 2 2 1 CHORD CS PF04969.16 KEZ44417.1 - 4.1e-10 40.5 0.1 6.9e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 CS domain DUF5082 PF16888.5 KEZ44417.1 - 0.22 11.8 0.2 0.45 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Dicty_REP PF05086.12 KEZ44417.1 - 1.7 6.5 7.7 2.7 5.9 7.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOG2 PF10428.9 KEZ44417.1 - 1.9 7.6 13.6 0.033 13.4 6.8 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein WH2 PF02205.20 KEZ44418.1 - 5e-09 35.7 0.7 5e-09 35.7 0.7 2.0 2 0 0 2 2 2 1 WH2 motif AAA_11 PF13086.6 KEZ44419.1 - 3.1e-58 197.6 0.1 5.8e-58 196.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KEZ44419.1 - 4.3e-45 153.8 0.0 7.4e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ44419.1 - 1.4e-10 41.2 0.0 2.3e-09 37.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ44419.1 - 5.1e-08 33.4 0.0 2.1e-07 31.4 0.0 2.1 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.9 KEZ44419.1 - 1.3e-06 27.9 0.1 8.8e-06 25.2 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KEZ44419.1 - 1.1e-05 25.5 0.0 5.8e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KEZ44419.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KEZ44419.1 - 0.00021 21.6 0.2 0.0024 18.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KEZ44419.1 - 0.00053 19.9 0.0 0.03 14.2 0.0 2.4 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 KEZ44419.1 - 0.00056 19.7 0.0 0.95 9.2 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KEZ44419.1 - 0.0006 20.2 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KEZ44419.1 - 0.00071 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 KEZ44419.1 - 0.0012 18.6 0.0 0.041 13.7 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 KEZ44419.1 - 0.0051 16.8 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.9 KEZ44419.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 KEZ44419.1 - 0.022 14.5 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 KEZ44419.1 - 0.026 14.5 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 KEZ44419.1 - 0.026 14.0 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 KEZ44419.1 - 0.028 14.8 0.0 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) 4HB_MCP_1 PF12729.7 KEZ44419.1 - 0.03 13.9 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_25 PF13481.6 KEZ44419.1 - 0.031 13.8 0.6 1 8.9 0.0 3.3 2 2 0 4 4 4 0 AAA domain AAA_24 PF13479.6 KEZ44419.1 - 0.05 13.3 0.1 0.31 10.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ44419.1 - 0.071 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KEZ44419.1 - 0.079 13.5 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ribosomal_L30_N PF08079.12 KEZ44419.1 - 0.13 12.6 2.9 0.32 11.3 2.9 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain DUF202 PF02656.15 KEZ44420.1 - 1.2e-20 73.7 1.7 1.2e-20 73.7 1.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Rax2 PF12768.7 KEZ44420.1 - 0.19 11.2 0.3 0.28 10.6 0.3 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity zf-C2H2 PF00096.26 KEZ44421.1 - 5.7e-13 48.5 11.0 1.9e-06 28.0 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ44421.1 - 3.6e-08 33.6 8.9 0.0022 18.7 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEZ44421.1 - 3.8e-08 33.4 12.0 2e-07 31.1 4.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KEZ44421.1 - 1e-06 28.9 3.9 0.00029 21.1 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KEZ44421.1 - 5.4e-06 26.6 3.5 0.0035 17.6 0.6 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KEZ44421.1 - 2.4e-05 24.2 8.3 0.0062 16.5 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KEZ44421.1 - 0.023 14.3 3.3 2.2 8.0 0.2 2.5 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KEZ44421.1 - 0.027 14.5 1.5 0.027 14.5 1.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf_UBZ PF18439.1 KEZ44421.1 - 0.05 13.2 1.6 2.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KEZ44421.1 - 0.26 12.0 1.9 6.5 7.4 0.3 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KEZ44421.1 - 0.44 10.3 5.4 8.6 6.2 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Actin_micro PF17003.5 KEZ44421.1 - 0.91 8.6 2.4 4.6 6.3 2.4 1.8 1 1 0 1 1 1 0 Putative actin-like family Zn-ribbon_8 PF09723.10 KEZ44421.1 - 2.6 8.3 4.9 9.5 6.4 0.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 KEZ44421.1 - 8.3 7.0 6.9 78 3.8 6.9 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger COesterase PF00135.28 KEZ44422.1 - 8.8e-72 242.6 0.0 1.1e-71 242.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ44422.1 - 4.9e-05 23.3 0.0 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.7 KEZ44423.1 - 1.9e-06 27.6 0.2 4.6e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ44423.1 - 0.0033 17.3 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Fungal_trans_2 PF11951.8 KEZ44424.1 - 5.9e-79 265.6 0.0 7.2e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ44424.1 - 1.9e-06 27.9 9.4 3e-06 27.2 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.29 KEZ44425.1 - 1.1e-05 25.9 0.0 2.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 KEZ44425.1 - 1.1e-05 25.4 0.0 3.3e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KEZ44425.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEZ44425.1 - 0.023 15.1 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 KEZ44425.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_9 PF15410.6 KEZ44425.1 - 0.2 12.0 0.0 0.5 10.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Sod_Fe_C PF02777.18 KEZ44426.1 - 1.2e-14 54.3 0.0 8.3e-12 45.2 0.0 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KEZ44426.1 - 0.0001 22.7 0.1 0.00016 22.1 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain STIMATE PF12400.8 KEZ44427.1 - 8.3e-41 139.5 2.7 8.3e-41 139.5 2.7 1.5 2 0 0 2 2 2 1 STIMATE family Virul_fac_BrkB PF03631.15 KEZ44427.1 - 0.04 13.5 5.9 0.37 10.4 2.5 2.3 2 0 0 2 2 2 0 Virulence factor BrkB Polysacc_synt PF01943.17 KEZ44427.1 - 0.58 9.5 4.9 0.6 9.4 0.7 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein APH PF01636.23 KEZ44428.1 - 5.2e-10 39.7 0.0 6.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ44428.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KEZ44428.1 - 0.00038 19.9 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 KEZ44428.1 - 0.0068 15.7 0.0 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 Fructosamine kinase TOM13 PF08219.11 KEZ44428.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein TOM13 adh_short PF00106.25 KEZ44430.1 - 1.3e-26 93.3 0.0 1.3e-23 83.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ44430.1 - 2.8e-15 56.5 0.0 5.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ44430.1 - 1.1e-08 35.3 0.1 2e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KEZ44430.1 - 0.00063 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KEZ44430.1 - 0.0017 18.2 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 KEZ44430.1 - 0.0025 17.3 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KEZ44430.1 - 0.0051 16.2 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KEZ44430.1 - 0.01 15.0 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein Pyr_redox PF00070.27 KEZ44430.1 - 0.021 15.4 0.0 0.72 10.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEZ44430.1 - 0.03 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KEZ44430.1 - 0.052 12.8 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KEZ44430.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans_2 PF11951.8 KEZ44431.1 - 0.00018 20.5 1.4 0.00024 20.0 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_14 PF01373.17 KEZ44431.1 - 0.26 10.2 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 RCR PF12273.8 KEZ44432.1 - 2e-14 54.3 27.8 4.9e-14 53.0 27.8 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red CYYR1 PF10873.8 KEZ44432.1 - 0.0036 17.8 2.8 0.0068 16.9 2.8 1.4 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Rhabdo_glycop PF00974.18 KEZ44432.1 - 0.18 10.3 0.8 0.23 9.9 0.8 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF2207 PF09972.9 KEZ44432.1 - 0.21 10.3 0.0 0.22 10.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FAA_hydrolase PF01557.18 KEZ44434.1 - 2e-52 178.0 0.0 2.4e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ZU5 PF00791.20 KEZ44434.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 ZU5 domain Ctr PF04145.15 KEZ44435.1 - 6.3e-29 101.5 12.5 4.8e-27 95.4 12.5 2.0 1 1 0 1 1 1 1 Ctr copper transporter family NUDIX PF00293.28 KEZ44436.1 - 4.8e-09 36.4 0.0 2.1e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain EXS PF03124.14 KEZ44437.1 - 8.3e-103 344.2 9.4 9.4e-103 344.0 9.4 1.0 1 0 0 1 1 1 1 EXS family zf-LYAR PF08790.11 KEZ44438.1 - 7.7e-14 51.3 4.0 7.7e-14 51.3 4.0 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger LacI PF00356.21 KEZ44438.1 - 0.04 13.7 0.2 0.077 12.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family zf-ACC PF17848.1 KEZ44438.1 - 0.16 12.0 0.7 0.36 11.0 0.7 1.6 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain Hydrolase_4 PF12146.8 KEZ44439.1 - 2.1e-17 63.2 0.1 7.3e-12 45.1 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ44439.1 - 9e-12 45.2 0.4 1.6e-08 34.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ44439.1 - 6.2e-05 23.7 0.0 0.00012 22.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KEZ44439.1 - 0.00012 20.9 0.0 0.18 10.4 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 KEZ44439.1 - 0.00045 20.0 0.0 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 KEZ44439.1 - 0.0011 18.4 0.0 0.0068 15.9 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEZ44439.1 - 0.0013 18.6 0.0 0.31 10.8 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase DUF818 PF05677.12 KEZ44439.1 - 0.0014 17.6 0.1 0.002 17.1 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 KEZ44439.1 - 0.0039 16.8 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 KEZ44439.1 - 0.007 16.3 0.0 0.38 10.7 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 KEZ44439.1 - 0.1 12.2 0.0 5.3 6.6 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 KEZ44439.1 - 0.14 11.9 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold R3H PF01424.22 KEZ44440.1 - 3.6e-15 55.7 0.1 7.4e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 R3H domain Dehyd-heme_bind PF09098.10 KEZ44440.1 - 0.068 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding WSC PF01822.19 KEZ44442.1 - 4e-87 286.5 73.2 6.6e-19 67.9 13.8 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 KEZ44442.1 - 1.3e-26 93.3 0.0 2.7e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KEZ44442.1 - 2.3e-22 79.1 0.0 4.4e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 KEZ44442.1 - 0.19 11.8 1.3 2.2 8.4 0.0 3.5 5 0 0 5 5 5 0 Kelch motif LCE6A PF15858.5 KEZ44442.1 - 3.2 8.6 9.8 1.4e+02 3.3 3.0 4.4 3 0 0 3 3 3 0 Late cornified envelope protein 6A family Dopey_N PF04118.14 KEZ44444.1 - 5.4e-121 403.4 0.0 1.1e-119 399.1 0.0 2.5 2 0 0 2 2 2 2 Dopey, N-terminal Methyltransf_15 PF09445.10 KEZ44445.1 - 7.5e-42 142.7 0.0 1e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KEZ44445.1 - 7.1e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KEZ44445.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_5 PF01795.19 KEZ44445.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family tRNA_U5-meth_tr PF05958.11 KEZ44445.1 - 0.062 12.3 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DNA_methylase PF00145.17 KEZ44445.1 - 0.087 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase MTS PF05175.14 KEZ44445.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 KEZ44445.1 - 0.17 11.5 0.1 0.28 10.8 0.1 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 GRASP55_65 PF04495.14 KEZ44446.1 - 7.4e-49 165.6 0.0 5.4e-48 162.8 0.0 1.9 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KEZ44446.1 - 0.00033 20.4 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain DAD PF02109.16 KEZ44447.1 - 1.6e-47 160.3 3.0 1.9e-47 160.0 3.0 1.0 1 0 0 1 1 1 1 DAD family Tmemb_14 PF03647.13 KEZ44448.1 - 8.4e-23 80.9 7.9 9.6e-23 80.7 7.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Cmc1 PF08583.10 KEZ44449.1 - 5.5e-15 55.1 2.1 6.6e-15 54.9 2.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 KEZ44449.1 - 0.29 11.5 2.3 0.58 10.6 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Prefoldin_2 PF01920.20 KEZ44450.1 - 2.3e-23 82.2 8.0 2.7e-23 82.0 8.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KEZ44450.1 - 0.019 14.9 5.3 0.41 10.6 5.3 2.1 1 1 0 1 1 1 0 Prefoldin subunit DUF148 PF02520.17 KEZ44450.1 - 0.022 14.9 5.6 0.038 14.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 ATPase PF06745.13 KEZ44450.1 - 0.033 13.5 0.5 0.27 10.5 0.1 2.0 1 1 1 2 2 2 0 KaiC RUN PF02759.19 KEZ44450.1 - 0.034 14.1 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 RUN domain DUF2205 PF10224.9 KEZ44450.1 - 0.49 10.4 3.8 0.64 10.0 0.6 2.1 2 0 0 2 2 2 0 Short coiled-coil protein CBFD_NFYB_HMF PF00808.23 KEZ44451.1 - 2.1e-21 76.0 4.0 7e-20 71.1 4.0 2.2 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_C1_2 PF03051.15 KEZ44451.1 - 0.033 13.0 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Histone PF00125.24 KEZ44451.1 - 0.068 13.5 0.2 0.52 10.7 0.2 2.2 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4110 PF13422.6 KEZ44452.1 - 3.3e-29 100.8 0.7 3.3e-29 100.8 0.7 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KEZ44452.1 - 4.2e-26 90.7 11.7 4.8e-09 36.1 0.0 6.9 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 KEZ44452.1 - 1.5e-22 79.4 9.8 2.8e-08 33.8 0.1 6.2 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KEZ44452.1 - 8.5e-22 76.7 0.3 1.1e-06 28.4 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KEZ44452.1 - 2e-17 62.4 2.6 0.00078 19.3 0.0 5.9 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 KEZ44452.1 - 1.3e-14 53.9 2.1 0.0042 17.3 0.1 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KEZ44452.1 - 4.8e-11 42.1 0.3 0.033 13.8 0.0 4.9 4 1 0 4 4 4 3 Kelch motif TFIIF_alpha PF05793.12 KEZ44452.1 - 4.7 5.7 27.3 0.097 11.2 9.5 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Thioredoxin PF00085.20 KEZ44454.1 - 2e-61 204.4 3.5 4.9e-30 103.6 0.0 4.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KEZ44454.1 - 1.3e-46 158.8 0.1 4.8e-35 121.1 0.0 3.7 2 1 1 3 3 3 3 Thioredoxin-like domain WLM PF08325.10 KEZ44454.1 - 4.4e-28 98.6 0.0 1.4e-27 97.1 0.0 1.9 1 1 0 1 1 1 1 WLM domain Calsequestrin PF01216.17 KEZ44454.1 - 4.6e-08 32.5 0.1 8.7e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 Calsequestrin DUF45 PF01863.17 KEZ44454.1 - 1.6e-07 31.6 0.3 6.4e-07 29.6 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function DUF45 Thioredoxin_7 PF13899.6 KEZ44454.1 - 3.7e-07 30.2 0.0 0.035 14.3 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KEZ44454.1 - 4.9e-07 29.7 0.1 0.0071 16.3 0.0 3.0 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KEZ44454.1 - 1.2e-06 28.7 0.0 0.018 15.4 0.0 3.5 4 0 0 4 4 3 2 Thioredoxin-like Redoxin PF08534.10 KEZ44454.1 - 7.5e-06 25.7 1.6 0.24 11.1 0.0 3.6 3 0 0 3 3 3 2 Redoxin Thioredoxin_2 PF13098.6 KEZ44454.1 - 1.1e-05 25.9 0.1 0.16 12.4 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KEZ44454.1 - 3.5e-05 23.3 0.1 0.27 10.6 0.0 3.0 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family ERp29_N PF07912.13 KEZ44454.1 - 0.02 15.0 0.1 7.2 6.8 0.0 3.4 3 1 0 3 3 3 0 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 KEZ44454.1 - 0.3 11.2 1.8 6.9 6.8 0.1 3.1 2 0 0 2 2 2 0 Thioredoxin Enolase_C PF00113.22 KEZ44455.1 - 1.9e-152 506.6 0.0 2.6e-152 506.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KEZ44455.1 - 2.6e-58 195.8 0.1 4.7e-58 195.0 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KEZ44455.1 - 0.00032 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KEZ44455.1 - 0.018 14.2 0.2 0.8 8.8 0.1 2.8 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Mad3_BUB1_I PF08311.12 KEZ44456.1 - 4.2e-41 139.8 0.6 7.5e-41 139.0 0.6 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KEZ44456.1 - 1.3e-08 34.6 0.0 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KEZ44456.1 - 1.8e-07 31.2 0.0 5.2e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 KEZ44456.1 - 0.0046 16.3 0.0 0.016 14.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KEZ44456.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein ATP-synt_J PF04911.12 KEZ44456.1 - 0.045 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase j chain AP_endonuc_2 PF01261.24 KEZ44457.1 - 1e-33 116.6 0.1 1.4e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAGAT PF03982.13 KEZ44458.1 - 3.9e-92 308.3 0.0 5.1e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase zf-H2C2_2 PF13465.6 KEZ44459.1 - 1.4e-16 60.0 21.2 2e-08 34.3 2.9 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KEZ44459.1 - 6e-10 39.0 25.1 0.003 17.9 7.5 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ44459.1 - 2.3e-07 31.1 21.7 0.034 15.0 6.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Rpr2 PF04032.16 KEZ44459.1 - 0.0013 19.0 0.2 0.073 13.4 0.0 2.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Rad50_zn_hook PF04423.14 KEZ44459.1 - 0.0014 18.4 1.6 0.61 10.0 0.2 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif GAGA PF09237.11 KEZ44459.1 - 0.0052 16.6 6.2 3.3 7.6 0.1 3.9 2 1 2 4 4 4 1 GAGA factor zf-C2H2_6 PF13912.6 KEZ44459.1 - 0.012 15.6 18.4 0.12 12.4 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 KEZ44459.1 - 0.047 13.8 7.1 0.09 12.9 2.9 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 KEZ44459.1 - 0.07 13.0 2.5 12 5.9 0.4 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (1 copy) HypA PF01155.19 KEZ44459.1 - 0.15 12.1 1.2 0.34 11.0 1.2 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ADIP PF11559.8 KEZ44459.1 - 0.18 11.9 1.3 0.39 10.8 1.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Zn_Tnp_IS1595 PF12760.7 KEZ44459.1 - 0.58 10.2 8.3 1.5 8.9 3.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-XS PF03470.14 KEZ44459.1 - 1.1 9.6 6.4 8.7 6.7 0.4 3.0 2 1 1 3 3 3 0 XS zinc finger domain zf-C2H2_jaz PF12171.8 KEZ44459.1 - 1.6 9.1 9.2 0.72 10.2 1.7 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 KEZ44459.1 - 6.6 6.8 6.7 29 4.8 6.5 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 KEZ44459.1 - 7 7.0 12.7 22 5.5 7.1 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KEZ44459.1 - 7.3 7.1 14.9 0.71 10.4 2.2 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.6 KEZ44459.1 - 9.3 6.1 6.0 37 4.2 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.12 KEZ44459.1 - 9.4 6.6 8.8 1.8e+02 2.5 0.1 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain SUN PF03856.13 KEZ44460.1 - 3.7e-94 314.8 8.3 4.6e-94 314.5 8.3 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Trypan_PARP PF05887.11 KEZ44460.1 - 4.3e-05 23.5 12.8 7.6e-05 22.7 12.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 KEZ44461.1 - 4.5e-07 29.1 28.0 4.5e-07 29.1 28.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ44461.1 - 0.0017 17.3 5.2 0.0017 17.3 5.2 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Folate_carrier PF01770.18 KEZ44461.1 - 0.013 14.2 1.0 0.022 13.5 1.0 1.3 1 0 0 1 1 1 0 Reduced folate carrier UDPGP PF01704.18 KEZ44462.1 - 1.3e-189 630.1 0.0 1.6e-189 629.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3605 PF12239.8 KEZ44463.1 - 9.9e-55 185.1 0.0 1.3e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.18 KEZ44464.1 - 6e-22 78.3 0.0 6.5e-11 42.8 0.0 3.3 2 2 0 2 2 2 2 Dihydroneopterin aldolase SKG6 PF08693.10 KEZ44465.1 - 0.00012 21.4 0.3 0.0004 19.7 0.3 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KEZ44465.1 - 0.016 15.0 0.2 0.016 15.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TraL PF07178.11 KEZ44465.1 - 0.049 14.1 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 TraL protein DUF2207 PF09972.9 KEZ44465.1 - 0.4 9.4 6.2 0.68 8.6 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) zf-IS66 PF13005.7 KEZ44465.1 - 0.48 10.9 1.4 0.59 10.6 0.1 1.8 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-LITAF-like PF10601.9 KEZ44465.1 - 6.7 7.0 6.6 1.2 9.5 1.0 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain SHS2_Rpb7-N PF03876.17 KEZ44466.1 - 1.6e-13 50.8 0.0 2.6e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KEZ44466.1 - 1.2e-12 47.9 0.0 2e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KEZ44466.1 - 0.029 14.6 0.1 0.063 13.5 0.1 1.5 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 DUF962 PF06127.11 KEZ44467.1 - 1.2e-26 92.5 0.7 1.6e-26 92.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF3262 PF11660.8 KEZ44467.1 - 0.1 13.0 1.9 0.73 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) MerE PF05052.12 KEZ44467.1 - 0.27 11.2 2.7 0.59 10.1 2.7 1.5 1 0 0 1 1 1 0 MerE protein DUF3306 PF11748.8 KEZ44468.1 - 3.7 8.5 8.0 9.3 7.1 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) AAA_16 PF13191.6 KEZ44469.1 - 2.7e-13 50.7 0.0 3.1e-12 47.2 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ44469.1 - 2.3e-12 47.3 0.0 5.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ44469.1 - 1.5e-11 44.9 0.1 3.5e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 KEZ44469.1 - 1.8e-06 27.8 0.1 1.8e-05 24.6 0.1 2.5 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain TniB PF05621.11 KEZ44469.1 - 1.9e-06 27.4 0.0 4.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 KEZ44469.1 - 9.5e-06 25.2 0.1 2.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_10 PF17872.1 KEZ44469.1 - 3.4e-05 23.9 0.0 8.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KEZ44469.1 - 9.8e-05 22.7 0.1 0.00026 21.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KEZ44469.1 - 0.00085 19.4 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KEZ44469.1 - 0.00098 18.4 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA_5 PF07728.14 KEZ44469.1 - 0.0013 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KEZ44469.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ44469.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Rad17 PF03215.15 KEZ44469.1 - 0.0044 17.0 0.1 0.0098 15.8 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain ATPase_2 PF01637.18 KEZ44469.1 - 0.018 15.0 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KEZ44469.1 - 0.018 14.8 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ44469.1 - 0.031 14.2 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KEZ44469.1 - 0.031 14.7 0.0 0.084 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KEZ44469.1 - 0.033 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF815 PF05673.13 KEZ44469.1 - 0.043 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_32 PF13654.6 KEZ44469.1 - 0.048 12.4 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rrf2 PF02082.20 KEZ44469.1 - 0.089 13.2 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator T2SSE PF00437.20 KEZ44469.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.14 KEZ44469.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA_2 PF07724.14 KEZ44469.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 KEZ44469.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 KEZ44469.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DEAD PF00270.29 KEZ44469.1 - 0.26 11.0 2.7 0.46 10.2 1.2 2.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase PBP1_TM PF14812.6 KEZ44469.1 - 2.3 8.6 6.2 6.2 7.3 6.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arrestin_N PF00339.29 KEZ44470.1 - 9.8e-16 58.1 0.0 1.7e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KEZ44470.1 - 7.2e-06 26.5 0.1 9.9e-05 22.8 0.2 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF836 PF05768.14 KEZ44471.1 - 7.4e-16 58.3 0.0 8.6e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KEZ44471.1 - 0.00047 20.3 0.0 0.00086 19.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 KEZ44471.1 - 0.11 12.4 0.1 0.27 11.0 0.0 1.6 1 1 1 2 2 2 0 F plasmid transfer operon protein Fcf1 PF04900.12 KEZ44472.1 - 1.9e-32 111.6 0.0 2.9e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 KEZ44472.1 - 0.54 8.5 3.6 0.65 8.2 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PP2C PF00481.21 KEZ44473.1 - 0.00088 19.0 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KEZ44473.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PH PF00169.29 KEZ44474.1 - 5.7e-07 30.0 1.7 2.1e-06 28.2 0.0 2.6 3 1 0 3 3 3 1 PH domain Peptidase_S9_N PF02897.15 KEZ44474.1 - 0.068 12.0 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PH_9 PF15410.6 KEZ44474.1 - 0.086 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 KEZ44475.1 - 4.7e-59 199.9 0.0 1.1e-58 198.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44475.1 - 4.3e-29 101.6 0.0 8.9e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KEZ44475.1 - 1.9e-11 44.1 0.1 5.6e-08 33.0 0.1 2.8 2 0 0 2 2 2 2 FHA domain Kdo PF06293.14 KEZ44475.1 - 0.0024 17.3 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ44475.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Yop-YscD_cpl PF16697.5 KEZ44475.1 - 0.076 13.3 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RHH_1 PF01402.21 KEZ44475.1 - 0.17 11.9 1.8 0.61 10.1 1.8 1.9 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family TTSSLRR PF12468.8 KEZ44475.1 - 0.28 11.4 1.5 0.69 10.2 1.5 1.7 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein CRT10 PF08728.10 KEZ44476.1 - 3.4e-14 52.0 0.0 1.8e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 CRT10 CDC45 PF02724.14 KEZ44476.1 - 0.00019 19.9 7.4 0.00025 19.5 7.4 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 KEZ44476.1 - 0.36 10.2 24.3 0.65 9.4 24.3 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEZ44476.1 - 0.9 7.7 25.7 1.3 7.1 25.7 1.1 1 0 0 1 1 1 0 Nop14-like family Ammonium_transp PF00909.21 KEZ44477.1 - 1.5e-115 386.1 30.9 1.7e-115 385.9 30.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_2 PF00328.22 KEZ44478.1 - 6.2e-45 154.2 0.0 7.4e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3357 PF11837.8 KEZ44478.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Sigma_reg_N PF13800.6 KEZ44478.1 - 0.19 12.0 0.1 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TauD PF02668.16 KEZ44479.1 - 8.8e-28 97.8 0.1 1.1e-27 97.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEZ44479.1 - 0.0028 16.8 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 CsiD Ribul_P_3_epim PF00834.19 KEZ44479.1 - 0.16 11.3 0.1 8 5.8 0.0 2.1 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family EMP24_GP25L PF01105.24 KEZ44482.1 - 4.8e-45 153.7 0.0 5.5e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.21 KEZ44483.1 - 2.5e-79 264.8 0.2 2.9e-79 264.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEZ44483.1 - 2e-14 53.4 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KEZ44483.1 - 2.6e-14 53.4 0.0 3.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KEZ44483.1 - 2.3e-13 50.0 1.3 3.3e-09 36.4 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KEZ44483.1 - 3.7e-13 49.4 0.0 4.1e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KEZ44483.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEZ44483.1 - 2e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KEZ44483.1 - 0.0052 16.1 0.3 0.021 14.1 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase zf-C2H2 PF00096.26 KEZ44485.1 - 3.6e-21 74.4 29.0 5.6e-05 23.4 0.3 7.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ44485.1 - 2.3e-17 62.2 24.3 0.0015 19.2 0.6 7.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEZ44485.1 - 1e-15 57.4 32.1 7e-07 29.4 0.3 6.2 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.6 KEZ44485.1 - 2.1e-11 43.5 18.2 0.025 14.6 0.2 5.2 4 1 1 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ44485.1 - 2.3e-06 27.7 13.5 0.0014 18.8 0.8 4.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ44485.1 - 0.004 17.5 13.2 0.31 11.5 0.2 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KEZ44485.1 - 0.022 15.4 13.1 1.5 9.5 1.3 4.4 4 1 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 KEZ44485.1 - 0.15 12.1 11.1 3.2 7.9 0.3 4.2 1 1 2 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.6 KEZ44485.1 - 0.18 11.7 10.0 0.8 9.7 0.2 4.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type BolA PF01722.18 KEZ44485.1 - 0.24 11.7 1.0 5.7 7.3 0.2 2.7 2 1 1 3 3 3 0 BolA-like protein zf-C2H2_aberr PF17017.5 KEZ44485.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.0 1 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 KEZ44485.1 - 0.92 9.3 10.3 11 5.9 0.1 4.6 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 KEZ44485.1 - 2.7 7.9 5.0 14 5.6 0.1 3.4 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 KEZ44485.1 - 4 7.8 20.3 1.6 9.1 1.2 4.4 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Ribosomal_L29 PF00831.23 KEZ44486.1 - 6.6e-17 61.2 2.8 6.6e-17 61.2 2.8 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein Phe_tRNA-synt_N PF02912.18 KEZ44486.1 - 0.0037 17.1 0.5 0.011 15.6 0.5 1.8 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain AICARFT_IMPCHas PF01808.18 KEZ44487.1 - 4.1e-89 298.9 0.0 5.3e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KEZ44487.1 - 5.7e-25 87.3 0.0 1.1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain V-SNARE_C PF12352.8 KEZ44488.1 - 8.3e-14 51.6 5.4 6.2e-13 48.8 0.0 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus FTA4 PF13093.6 KEZ44488.1 - 0.0086 16.0 6.8 0.81 9.5 7.4 2.7 1 1 1 2 2 2 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 STAT_alpha PF01017.20 KEZ44488.1 - 0.077 12.9 4.5 0.088 12.7 1.1 2.2 1 1 0 2 2 2 0 STAT protein, all-alpha domain Syntaxin_2 PF14523.6 KEZ44488.1 - 0.2 12.0 7.0 0.89 10.0 0.4 2.9 1 1 0 2 2 2 0 Syntaxin-like protein Spc7 PF08317.11 KEZ44488.1 - 0.29 10.0 9.6 0.5 9.2 9.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1451 PF07295.11 KEZ44488.1 - 0.57 10.2 4.3 3 7.9 1.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF4404 PF14357.6 KEZ44488.1 - 0.85 10.3 6.3 0.19 12.4 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Snapin_Pallidin PF14712.6 KEZ44488.1 - 1.1 9.7 10.7 0.24 11.9 4.1 2.6 2 1 1 3 3 3 0 Snapin/Pallidin Atg14 PF10186.9 KEZ44488.1 - 2.1 7.3 11.1 27 3.7 0.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_10 PF05176.14 KEZ44489.1 - 1.8e-77 260.1 0.0 2.3e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.23 KEZ44490.1 - 9.7e-75 251.0 0.5 1.9e-74 250.0 0.5 1.5 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEZ44490.1 - 2.3e-18 65.8 0.1 5e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEZ44490.1 - 5.6e-13 49.0 1.6 8e-13 48.5 0.1 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KEZ44490.1 - 0.07 13.0 0.5 0.25 11.2 0.2 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like AAA_18 PF13238.6 KEZ44491.1 - 1.5e-10 41.8 0.0 4e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KEZ44491.1 - 3.8e-09 36.9 0.0 4.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KEZ44491.1 - 6.5e-09 36.1 0.0 1.4e-08 35.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KEZ44491.1 - 9.4e-06 26.1 0.0 2e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KEZ44491.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase dNK PF01712.19 KEZ44491.1 - 0.00031 20.7 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 KEZ44491.1 - 0.00045 20.7 0.0 0.00083 19.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KEZ44491.1 - 0.00053 20.0 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KEZ44491.1 - 0.0058 17.1 0.1 0.03 14.8 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ44491.1 - 0.0074 16.6 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KEZ44491.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KEZ44491.1 - 0.037 14.3 0.0 0.074 13.3 0.0 1.6 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KEZ44491.1 - 0.038 13.9 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 KEZ44491.1 - 0.04 14.3 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KEZ44491.1 - 0.046 13.6 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 NTPase DNA_pol3_delta2 PF13177.6 KEZ44491.1 - 0.057 13.2 0.0 0.089 12.6 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_29 PF13555.6 KEZ44491.1 - 0.098 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KEZ44491.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Herpes_Helicase PF02689.14 KEZ44491.1 - 0.15 9.9 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Helicase Peptidase_M49 PF03571.15 KEZ44492.1 - 4.4e-247 820.9 0.0 5.2e-247 820.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 CdiA_C_tRNase PF18664.1 KEZ44492.1 - 0.017 15.3 0.1 0.047 13.9 0.1 1.7 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain 2C_adapt PF08793.10 KEZ44492.1 - 0.081 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain Glucosamine_iso PF01182.20 KEZ44492.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L6e PF01159.19 KEZ44493.1 - 5.5e-40 136.4 0.7 5.5e-40 136.4 0.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e HCNGP PF07818.13 KEZ44494.1 - 1.2e-30 106.0 0.0 1.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein DUF3712 PF12505.8 KEZ44495.1 - 3.1e-24 85.6 2.8 7.3e-24 84.4 2.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) FMN_dh PF01070.18 KEZ44496.1 - 8.9e-104 347.2 0.0 1.1e-103 347.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KEZ44496.1 - 2.7e-20 72.3 0.0 6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KEZ44496.1 - 1.1e-07 31.3 0.1 1.9e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KEZ44496.1 - 4.4e-07 29.2 0.0 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KEZ44496.1 - 0.02 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KEZ44496.1 - 0.022 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family NMO PF03060.15 KEZ44496.1 - 0.053 12.9 1.3 0.12 11.7 0.2 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.21 KEZ44496.1 - 0.07 12.3 0.0 0.1 11.8 0.0 1.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Lipase_GDSL_2 PF13472.6 KEZ44497.1 - 2.3e-18 67.2 0.0 7.4e-18 65.6 0.0 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family HSCB_C PF07743.13 KEZ44497.1 - 2e-09 37.8 7.2 2e-09 37.8 7.2 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain Lipase_GDSL PF00657.22 KEZ44497.1 - 3.1e-07 30.6 0.0 8.4e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DnaJ PF00226.31 KEZ44497.1 - 0.00074 19.6 0.2 0.0024 17.9 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Pex14_N PF04695.13 KEZ44497.1 - 3.8 8.1 9.3 11 6.7 0.2 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PCI PF01399.27 KEZ44498.1 - 5e-11 43.0 0.0 8.5e-10 39.1 0.0 2.8 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 KEZ44498.1 - 3.1e-05 23.7 0.1 7.8e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 26S proteasome subunit RPN7 EF-G-binding_N PF07299.11 KEZ44498.1 - 0.11 13.1 0.1 12 6.5 0.0 3.1 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal FANC_SAP PF18081.1 KEZ44498.1 - 7.3 6.8 6.3 19 5.5 0.0 3.6 4 0 0 4 4 4 0 Fanconi anemia-associated nuclease SAP domain F-box-like PF12937.7 KEZ44499.1 - 0.0013 18.6 0.3 0.0037 17.1 0.3 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KEZ44499.1 - 0.17 11.7 7.6 0.03 14.1 1.4 2.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KEZ44499.1 - 0.36 11.3 10.5 0.16 12.4 2.0 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) SNF2_N PF00176.23 KEZ44500.1 - 9.8e-37 126.5 0.0 7.4e-34 117.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ44500.1 - 5.9e-08 33.0 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ44500.1 - 0.019 15.0 0.0 7.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Questin_oxidase PF14027.6 KEZ44501.1 - 1.1e-89 301.4 0.4 2e-89 300.5 0.4 1.5 1 0 0 1 1 1 1 Questin oxidase-like Rad17 PF03215.15 KEZ44501.1 - 8.6e-21 74.7 0.0 1.5e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KEZ44501.1 - 0.00033 21.1 0.0 0.0016 18.9 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ44501.1 - 0.0031 17.9 0.1 0.022 15.1 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KEZ44501.1 - 0.0096 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KEZ44501.1 - 0.087 12.5 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KEZ44501.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KEZ44501.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.13 KEZ44501.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KEZ44501.1 - 0.15 12.3 0.0 0.54 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain SPX PF03105.19 KEZ44503.1 - 0.56 10.1 18.4 2 8.3 17.4 2.1 2 0 0 2 2 2 0 SPX domain Macoilin PF09726.9 KEZ44503.1 - 0.82 8.2 9.9 1.2 7.6 9.9 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 KEZ44503.1 - 0.82 8.4 13.3 0.66 8.8 11.8 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain PRCC PF10253.9 KEZ44503.1 - 3.9 8.2 16.2 0.44 11.3 10.1 2.3 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting QWRF PF04484.12 KEZ44503.1 - 9.2 5.9 14.4 18 4.9 14.4 1.5 1 0 0 1 1 1 0 QWRF family Ppx-GppA PF02541.16 KEZ44504.1 - 1.5e-26 93.5 0.0 2.7e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family O-FucT PF10250.9 KEZ44504.1 - 4.5e-10 39.7 0.0 1.4e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase BTB PF00651.31 KEZ44505.1 - 0.0057 16.9 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Topo_C_assoc PF14370.6 KEZ44505.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal topoisomerase domain Oxidored_FMN PF00724.20 KEZ44506.1 - 9.8e-67 225.6 0.0 1.9e-66 224.7 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SUI1 PF01253.22 KEZ44507.1 - 5.7e-13 49.2 5.4 1.6e-12 47.7 0.5 2.9 2 1 0 2 2 2 1 Translation initiation factor SUI1 Dermcidin PF15291.6 KEZ44507.1 - 0.036 14.6 3.1 0.053 14.1 3.1 1.2 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Nbl1_Borealin_N PF10444.9 KEZ44508.1 - 4.9e-21 74.1 3.3 8e-21 73.4 3.3 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 KEZ44509.1 - 4.1e-27 94.9 0.0 8.4e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEZ44509.1 - 8.1e-10 39.2 0.2 1.1e-09 38.8 0.2 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KEZ44509.1 - 5.3e-08 32.9 0.0 7.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KEZ44509.1 - 0.011 15.6 0.6 0.031 14.2 0.6 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Ala_racemase_N PF01168.20 KEZ44509.1 - 0.044 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain DUF4355 PF14265.6 KEZ44509.1 - 2.7 8.3 10.0 0.43 10.8 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Sybindin PF04099.12 KEZ44510.1 - 3.6e-53 179.3 0.0 4.1e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KEZ44510.1 - 9e-08 32.3 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RNA_pol_Rpb4 PF03874.16 KEZ44511.1 - 6.1e-25 87.9 4.9 7.6e-25 87.6 4.9 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 MIF4G_like_2 PF09090.11 KEZ44511.1 - 0.06 12.8 0.9 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 MIF4G like CPL PF08144.11 KEZ44512.1 - 2.3e-38 131.7 0.1 4.8e-35 121.0 0.0 3.9 4 0 0 4 4 4 1 CPL (NUC119) domain SCHIP-1 PF10148.9 KEZ44512.1 - 0.0013 18.4 2.3 0.0022 17.6 2.3 1.3 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 SNAD1 PF18744.1 KEZ44512.1 - 0.0073 16.2 0.0 0.93 9.3 0.0 2.3 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 1 CTI PF06934.11 KEZ44512.1 - 0.017 13.7 0.0 0.032 12.8 0.0 1.4 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) SNAD2 PF18745.1 KEZ44512.1 - 0.02 14.6 0.2 0.048 13.4 0.2 1.6 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 VTC PF09359.10 KEZ44512.1 - 0.22 10.9 3.8 0.44 9.9 3.8 1.4 1 0 0 1 1 1 0 VTC domain DUF4065 PF13274.6 KEZ44512.1 - 3 8.8 6.4 4.1 8.3 0.1 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF4065) PITH PF06201.13 KEZ44515.1 - 7.6e-34 117.1 0.0 1.2e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KEZ44515.1 - 1.8e-18 66.4 0.0 2.8e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KEZ44515.1 - 5.8e-05 23.5 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KEZ44515.1 - 0.00012 21.5 0.1 0.00017 21.0 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KEZ44515.1 - 0.007 16.7 0.0 0.15 12.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 KEZ44515.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE VCBS PF13517.6 KEZ44515.1 - 0.048 14.3 0.0 3.2 8.4 0.0 2.9 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Thioredoxin_6 PF13848.6 KEZ44515.1 - 0.1 12.5 0.1 0.96 9.3 0.0 2.2 2 1 1 3 3 3 0 Thioredoxin-like domain BTB PF00651.31 KEZ44516.1 - 0.0026 18.0 0.0 0.0045 17.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RecX PF02631.16 KEZ44516.1 - 0.065 13.7 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 RecX family G-patch PF01585.23 KEZ44517.1 - 0.00079 19.3 0.0 0.0022 17.8 0.0 1.9 1 0 0 1 1 1 1 G-patch domain Fungal_trans PF04082.18 KEZ44519.1 - 1.3e-06 27.7 0.1 2.5e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ44519.1 - 1.5e-05 25.0 7.7 3.1e-05 24.0 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4834 PF16118.5 KEZ44519.1 - 1.6 9.7 5.5 34 5.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SidE PF12252.8 KEZ44521.1 - 0.063 10.8 6.6 0.068 10.7 6.6 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein FAM76 PF16046.5 KEZ44521.1 - 0.24 10.7 9.0 0.29 10.4 9.0 1.1 1 0 0 1 1 1 0 FAM76 protein Exonuc_VII_L PF02601.15 KEZ44521.1 - 0.86 9.1 6.7 1.1 8.8 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit COX17 PF05051.13 KEZ44522.1 - 1.5e-20 73.2 7.3 1.8e-20 73.0 7.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DnaJ PF00226.31 KEZ44523.1 - 1.6e-19 69.8 0.8 2.5e-19 69.2 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KEZ44523.1 - 5.2 7.4 9.9 0.059 13.7 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF456) GPI-anchored PF10342.9 KEZ44524.1 - 1.1e-08 35.7 0.0 2.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_18 PF00704.28 KEZ44525.1 - 1.8e-79 267.7 0.8 2.3e-79 267.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 KEZ44525.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 AP_endonuc_2 PF01261.24 KEZ44525.1 - 0.095 12.1 0.1 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel LRR_6 PF13516.6 KEZ44527.1 - 7.8e-13 47.4 9.9 0.0048 16.8 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 KEZ44527.1 - 4.7e-07 30.0 10.6 0.033 14.6 0.1 5.4 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEZ44527.1 - 0.00019 21.5 6.2 8.2 7.4 0.4 6.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 KEZ44527.1 - 0.0049 16.6 10.6 0.28 11.0 0.3 4.8 4 1 0 4 4 4 1 Leucine rich repeat Occludin_ELL PF07303.13 KEZ44527.1 - 0.42 11.4 4.5 0.78 10.5 2.2 2.3 2 0 0 2 2 2 0 Occludin homology domain Radial_spoke PF04712.12 KEZ44527.1 - 1.5 7.7 16.1 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein zf-H2C2_2 PF13465.6 KEZ44528.1 - 8.6e-07 29.1 10.4 3.5e-06 27.2 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KEZ44528.1 - 2.5e-05 24.2 0.5 0.065 13.3 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ44528.1 - 2.7e-05 24.4 0.3 2.7e-05 24.4 0.3 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KEZ44528.1 - 8.8e-05 23.1 10.5 0.16 12.6 0.0 4.0 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KEZ44528.1 - 0.00046 20.8 3.9 0.013 16.3 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger ATG16 PF08614.11 KEZ44528.1 - 0.046 14.0 0.1 0.046 14.0 0.1 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KEZ44528.1 - 0.13 12.3 1.3 0.23 11.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3350 PF11830.8 KEZ44528.1 - 1.6 9.1 5.2 0.31 11.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) SUZ PF12752.7 KEZ44530.1 - 2.8e-07 31.2 2.6 2.8e-07 31.2 2.6 3.1 4 0 0 4 4 4 1 SUZ domain ATP_sub_h PF10775.9 KEZ44532.1 - 5.8e-25 87.1 0.2 8.5e-25 86.5 0.2 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Pkinase PF00069.25 KEZ44533.1 - 4.2e-69 232.8 0.0 5.4e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44533.1 - 5.5e-31 107.8 0.0 7.9e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KEZ44533.1 - 1.9e-14 54.1 3.4 2.8e-14 53.6 0.2 2.9 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KEZ44533.1 - 9.3e-10 38.3 0.0 2.5e-09 36.9 0.0 1.6 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 KEZ44533.1 - 2.8e-08 34.0 0.0 9.7e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KEZ44533.1 - 0.002 17.2 0.5 0.0047 15.9 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Adeno_E3_15_3 PF03307.14 KEZ44533.1 - 0.0023 17.9 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Adenovirus 15.3kD protein in E3 region Kdo PF06293.14 KEZ44533.1 - 0.012 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KEZ44533.1 - 0.074 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KEZ44533.1 - 0.2 11.2 0.2 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SWI-SNF_Ssr4 PF08549.10 KEZ44534.1 - 1.2e-269 897.0 0.7 1.3e-269 896.8 0.7 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) TPT PF03151.16 KEZ44535.1 - 1.9e-16 60.3 11.9 2.7e-16 59.8 11.9 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEZ44535.1 - 1.3e-05 25.4 30.0 0.0086 16.3 3.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family NfI_DNAbd_pre-N PF10524.9 KEZ44535.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Tom5 PF10642.9 KEZ44535.1 - 0.33 11.0 1.2 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase GH131_N PF18271.1 KEZ44536.1 - 4e-82 275.7 0.0 4.9e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 KEZ44536.1 - 0.015 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Zn_clus PF00172.18 KEZ44537.1 - 0.076 13.1 6.4 0.15 12.2 6.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PRA1 PF03208.19 KEZ44539.1 - 9.9e-31 106.3 3.2 1.4e-30 105.8 3.2 1.1 1 0 0 1 1 1 1 PRA1 family protein RXT2_N PF08595.11 KEZ44539.1 - 0.074 13.1 0.1 0.074 13.1 0.1 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF3246 PF11596.8 KEZ44539.1 - 0.085 12.3 3.3 0.17 11.3 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Rhodanese PF00581.20 KEZ44540.1 - 6e-13 49.3 0.0 1.5e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain SMP PF04927.12 KEZ44540.1 - 0.7 10.4 2.4 1.5 9.4 2.4 1.5 1 0 0 1 1 1 0 Seed maturation protein DNA_pol_phi PF04931.13 KEZ44541.1 - 3.9e-115 385.7 0.1 5.8e-115 385.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase phi DUF3473 PF11959.8 KEZ44541.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) RRN3 PF05327.11 KEZ44541.1 - 1.4 7.4 13.1 22 3.4 12.0 2.7 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 KEZ44541.1 - 4.5 6.5 19.3 9.5 5.4 19.3 1.5 1 0 0 1 1 1 0 BUD22 Proteasome PF00227.26 KEZ44542.1 - 1.9e-47 161.3 0.1 1.9e-32 112.3 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KEZ44542.1 - 1.4e-11 43.8 0.0 1.4e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DnaJ PF00226.31 KEZ44543.1 - 3.8e-11 42.9 1.1 9.4e-11 41.7 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain CwfJ_C_1 PF04677.15 KEZ44544.1 - 3.1e-24 85.2 0.0 1.3e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KEZ44544.1 - 2.2e-17 63.8 0.6 5.2e-17 62.6 0.6 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 tRNA_int_endo PF01974.17 KEZ44544.1 - 0.012 15.7 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain DRIM PF07539.12 KEZ44545.1 - 2.3e-185 617.5 0.4 3.3e-184 613.7 0.0 3.0 3 0 0 3 3 3 1 Down-regulated in metastasis BP28CT PF08146.12 KEZ44545.1 - 0.11 12.3 0.0 0.7 9.7 0.0 2.5 1 0 0 1 1 1 0 BP28CT (NUC211) domain Utp13 PF08625.11 KEZ44545.1 - 0.13 12.2 0.0 0.58 10.1 0.0 2.2 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Cullin PF00888.22 KEZ44546.1 - 4e-176 587.3 0.1 1e-175 585.9 0.0 1.6 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KEZ44546.1 - 1.6e-25 88.9 1.3 3.7e-25 87.7 1.3 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain MPC PF03650.13 KEZ44547.1 - 4.1e-36 123.5 0.0 5e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CPSase_L_D2 PF02786.17 KEZ44548.1 - 5.5e-80 267.8 0.2 8.6e-80 267.2 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KEZ44548.1 - 1.3e-69 234.0 0.0 2.1e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KEZ44548.1 - 6.2e-39 133.0 0.1 1.3e-38 131.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ44548.1 - 6e-32 110.0 0.0 1.8e-31 108.4 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KEZ44548.1 - 1.6e-27 96.7 0.0 4e-27 95.4 0.0 1.6 1 1 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KEZ44548.1 - 6e-19 67.6 2.5 1.4e-18 66.5 1.4 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KEZ44548.1 - 9.5e-10 38.4 0.0 2.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KEZ44548.1 - 1.4e-09 37.6 0.6 4.1e-06 26.5 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KEZ44548.1 - 2.9e-07 30.2 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KEZ44548.1 - 7.3e-05 22.9 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KEZ44548.1 - 0.0014 17.9 0.1 0.091 12.0 0.0 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 KEZ44548.1 - 0.0016 18.0 0.0 0.01 15.4 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 KEZ44548.1 - 0.0033 18.1 0.1 1.1 9.9 0.0 3.0 2 0 0 2 2 2 1 HlyD family secretion protein ATP-grasp_4 PF13535.6 KEZ44548.1 - 0.0034 17.0 0.1 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KEZ44548.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 KEZ44548.1 - 0.016 14.5 0.0 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KEZ44548.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.11 KEZ44548.1 - 0.047 13.1 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_YheCD PF14398.6 KEZ44548.1 - 0.066 12.5 0.0 2.9 7.0 0.0 2.4 2 0 0 2 2 2 0 YheC/D like ATP-grasp PYNP_C PF07831.13 KEZ44548.1 - 0.088 12.5 1.3 2.5 7.8 0.0 3.2 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.19 KEZ44548.1 - 0.14 12.1 0.2 0.62 10.0 0.2 2.1 1 0 0 1 1 1 0 Glycine cleavage H-protein Cyclin_N PF00134.23 KEZ44549.1 - 1.2e-09 38.0 0.1 2.5e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 KEZ44549.1 - 0.1 12.7 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat ABC_tran PF00005.27 KEZ44550.1 - 2.1e-36 125.5 0.0 7.4e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEZ44550.1 - 5.8e-26 91.8 33.5 3.4e-23 82.7 17.8 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KEZ44550.1 - 2.8e-07 30.7 0.0 2.1 8.1 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ44550.1 - 3.8e-07 29.8 0.3 0.89 8.9 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ44550.1 - 9.8e-05 22.0 0.1 0.3 10.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KEZ44550.1 - 0.0017 17.5 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KEZ44550.1 - 0.0021 18.1 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KEZ44550.1 - 0.0026 17.8 0.3 0.33 11.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 KEZ44550.1 - 0.0042 16.7 0.1 1.4 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KEZ44550.1 - 0.012 15.5 0.0 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 KEZ44550.1 - 0.043 13.5 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KEZ44550.1 - 0.051 12.9 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KEZ44550.1 - 0.063 13.4 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KEZ44550.1 - 0.11 12.8 0.5 9.3 6.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEZ44550.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_7 PF12775.7 KEZ44550.1 - 0.14 11.7 0.0 17 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KEZ44550.1 - 0.15 12.6 0.0 37 4.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KEZ44550.1 - 0.16 12.4 0.0 28 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain CDH-cyt PF16010.5 KEZ44551.1 - 6.2e-25 87.9 4.0 1.1e-24 87.1 4.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KEZ44551.1 - 5.3e-09 35.8 0.6 5.3e-09 35.8 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.17 KEZ44551.1 - 2.1e-07 31.2 1.3 4.5e-07 30.1 1.3 1.5 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 KEZ44551.1 - 4.2e-06 26.9 12.1 1e-05 25.7 12.1 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2231 PF09990.9 KEZ44551.1 - 0.59 10.6 8.4 0.39 11.2 5.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF3995 PF13160.6 KEZ44551.1 - 7.2 7.0 15.5 5.9 7.3 1.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) LSM PF01423.22 KEZ44552.1 - 7.3e-16 57.6 0.0 1.1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain FAP PF07174.11 KEZ44552.1 - 0.92 8.9 32.8 0.28 10.6 29.1 1.7 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) Ribosomal_L5_C PF00673.21 KEZ44553.1 - 1.8e-22 79.3 0.0 2.7e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KEZ44553.1 - 1.6e-20 73.2 0.1 3.3e-20 72.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 ATP-synt_ab PF00006.25 KEZ44554.1 - 1.5e-72 243.7 0.0 2.2e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KEZ44554.1 - 4.1e-47 159.6 0.2 6.9e-47 158.9 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KEZ44554.1 - 3.2e-15 56.4 3.0 1.1e-14 54.7 3.0 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Carb_kinase PF01256.17 KEZ44555.1 - 6.8e-54 182.9 0.1 9.2e-54 182.5 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KEZ44555.1 - 2.9e-05 23.6 0.0 7e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KEZ44555.1 - 0.037 13.3 0.0 0.09 12.1 0.0 1.6 2 0 0 2 2 2 0 pfkB family carbohydrate kinase CorA PF01544.18 KEZ44556.1 - 1.4e-35 123.0 0.1 1.3e-34 119.9 0.1 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Osmo_CC PF08946.10 KEZ44556.1 - 4 7.8 5.0 13 6.1 5.0 1.8 1 0 0 1 1 1 0 Osmosensory transporter coiled coil CBF PF03914.17 KEZ44557.1 - 7.8e-36 123.7 0.7 3.3e-35 121.6 0.1 2.3 3 0 0 3 3 3 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 KEZ44558.1 - 4e-53 179.4 5.6 5.1e-53 179.0 5.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) BON PF04972.17 KEZ44558.1 - 0.054 13.8 0.6 1.2 9.5 0.1 3.0 3 0 0 3 3 3 0 BON domain TSP_NTD PF17804.1 KEZ44558.1 - 0.27 11.5 4.0 0.39 11.0 4.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain MSC PF09402.10 KEZ44559.1 - 3.7e-114 381.7 0.0 5.3e-114 381.2 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KEZ44559.1 - 1e-17 63.5 0.1 1.8e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KEZ44559.1 - 0.0026 17.3 0.1 0.006 16.2 0.1 1.5 1 0 0 1 1 1 1 Thymopoietin protein FAD_binding_3 PF01494.19 KEZ44560.1 - 7.6e-21 74.7 0.0 2e-18 66.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KEZ44560.1 - 0.00012 21.2 0.8 0.0018 17.4 0.3 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEZ44560.1 - 0.0024 17.2 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEZ44560.1 - 0.0034 16.5 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KEZ44560.1 - 0.017 14.7 0.0 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ44560.1 - 0.022 15.0 0.1 0.08 13.2 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEZ44560.1 - 0.035 13.2 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KEZ44560.1 - 0.052 12.8 0.0 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KEZ44560.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Complex1_49kDa PF00346.19 KEZ44561.1 - 1.6e-123 411.1 0.0 2.2e-123 410.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KEZ44561.1 - 0.051 12.5 0.0 0.084 11.8 0.0 1.4 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 KEZ44562.1 - 9.4e-27 93.6 0.0 1.9e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KEZ44562.1 - 9e-20 69.9 0.0 1.3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 KEZ44563.1 - 3.2e-63 213.3 0.1 4.5e-63 212.9 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KEZ44563.1 - 6.2e-29 100.0 0.0 1e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 KEZ44563.1 - 6e-05 23.6 0.0 0.00054 20.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 KEZ44563.1 - 0.00051 20.1 0.5 0.0013 18.8 0.0 1.9 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KEZ44563.1 - 0.029 14.8 0.1 0.075 13.5 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KEZ44563.1 - 0.11 12.7 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Telomere_reg-2 PF10193.9 KEZ44564.1 - 1.9e-36 124.8 0.0 4.2e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein NESP55 PF06390.12 KEZ44564.1 - 0.078 12.6 3.0 0.14 11.7 3.0 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pkinase PF00069.25 KEZ44565.1 - 7.8e-54 182.8 0.0 1.1e-53 182.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44565.1 - 1.7e-40 138.9 0.0 2.6e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ44565.1 - 2.4e-05 23.8 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KEZ44565.1 - 0.0026 16.7 0.1 0.54 9.1 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 KEZ44565.1 - 0.011 14.5 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KEZ44565.1 - 0.038 13.9 0.1 0.29 11.0 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KEZ44565.1 - 0.05 13.0 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PocR PF10114.9 KEZ44565.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR DUF5560 PF17715.1 KEZ44566.1 - 5.6 6.4 7.6 0.44 10.0 0.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5560) SNase PF00565.17 KEZ44567.1 - 9.8e-24 83.9 0.0 1.2e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TFIIF_beta_N PF17683.1 KEZ44568.1 - 2.4e-31 109.2 0.0 4.4e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KEZ44568.1 - 2.3e-28 98.1 0.2 3.7e-28 97.5 0.2 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Band_7 PF01145.25 KEZ44569.1 - 4.9e-23 82.1 2.3 1.1e-22 80.9 2.3 1.7 1 0 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.23 KEZ44569.1 - 8.3e-18 63.9 0.1 1.6e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KEZ44569.1 - 1.8e-06 27.6 0.0 3.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like APH PF01636.23 KEZ44569.1 - 0.011 15.7 0.5 0.027 14.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ubiquitin_2 PF14560.6 KEZ44569.1 - 0.019 15.4 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 KEZ44569.1 - 0.17 11.8 0.0 0.64 10.0 0.0 1.9 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain AAA_11 PF13086.6 KEZ44569.1 - 0.22 11.3 1.8 0.4 10.4 1.8 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KEZ44570.1 - 6.1e-44 147.1 27.2 7.6e-07 29.7 0.4 11.4 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 KEZ44570.1 - 4.8e-20 71.9 0.1 9.8e-20 70.9 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KEZ44570.1 - 5.8e-17 61.8 5.7 0.0098 16.2 0.0 8.9 5 3 6 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 KEZ44570.1 - 1.1e-12 47.5 2.8 1.1e-12 47.4 0.8 2.1 2 0 0 2 2 2 1 LSM domain eIF2A PF08662.11 KEZ44570.1 - 3.8e-05 23.6 0.1 0.0062 16.4 0.0 3.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KEZ44570.1 - 5e-05 22.4 2.3 2.2 7.2 0.0 4.9 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KEZ44570.1 - 0.00022 20.0 5.6 0.4 9.3 0.0 4.9 4 1 0 5 5 5 2 Nucleoporin Nup120/160 Frtz PF11768.8 KEZ44570.1 - 0.0032 15.9 0.0 0.16 10.2 0.0 2.5 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz NINJA_B PF16136.5 KEZ44570.1 - 0.0074 16.7 0.2 0.018 15.4 0.2 1.6 1 0 0 1 1 1 1 Putative nuclear localisation signal WD40_like PF17005.5 KEZ44570.1 - 0.0091 15.3 0.0 7.6 5.8 0.0 3.4 3 0 0 3 3 3 1 WD40-like domain 7TMR-HDED PF07697.11 KEZ44570.1 - 0.036 14.2 1.6 0.053 13.6 0.1 2.0 2 0 0 2 2 2 0 7TM-HD extracellular Hfq PF17209.3 KEZ44570.1 - 0.084 12.5 0.1 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Hfq protein CorA PF01544.18 KEZ44571.1 - 7.5e-05 22.2 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 KEZ44572.1 - 5.4e-59 199.7 0.0 8.2e-58 195.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44572.1 - 1.5e-26 93.2 0.1 2e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KEZ44572.1 - 6.5e-05 22.0 0.1 0.0001 21.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEZ44572.1 - 0.00055 19.3 0.0 0.0015 18.0 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KEZ44572.1 - 0.002 17.5 1.0 0.0025 17.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEZ44572.1 - 0.0021 18.0 7.8 0.015 15.3 0.4 3.2 3 1 1 4 4 4 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEZ44572.1 - 0.059 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KEZ44572.1 - 0.32 10.6 1.2 0.89 9.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.8 KEZ44573.1 - 4.3e-142 473.3 4.2 5.1e-142 473.1 4.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 KEZ44573.1 - 5 7.4 12.8 10 6.4 2.2 3.1 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 KEZ44573.1 - 8.6 6.1 8.3 1.3 8.8 1.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Nefa_Nip30_N PF10187.9 KEZ44574.1 - 5.5e-30 103.8 16.0 5.5e-30 103.8 16.0 2.3 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 PKK PF12474.8 KEZ44574.1 - 9.9 6.3 25.7 0.96 9.6 7.1 2.2 1 1 1 2 2 2 0 Polo kinase kinase CRC_subunit PF08624.10 KEZ44575.1 - 1.2e-52 177.9 0.0 1.7e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Autophagy_act_C PF03987.15 KEZ44576.1 - 1.7e-13 50.9 0.5 2.9e-13 50.2 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 KEZ44577.1 - 0.026 14.3 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KEZ44578.1 - 1.8e-16 60.2 12.4 0.00029 21.6 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ44578.1 - 1.1e-06 28.8 0.0 0.15 12.3 0.0 4.3 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KEZ44578.1 - 0.034 14.1 0.0 6.4 6.9 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ribonuc_L-PSP PF01042.21 KEZ44579.1 - 5.3e-39 133.0 0.1 6.5e-39 132.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.18 KEZ44580.1 - 5.8e-84 281.5 15.7 1.1e-83 280.7 15.7 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KEZ44580.1 - 3.7e-70 235.6 8.0 3.7e-70 235.6 8.0 3.1 3 1 1 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KEZ44580.1 - 1.1e-19 71.0 0.4 3.2e-19 69.5 0.2 1.7 1 1 1 2 2 2 2 MIR domain YqzE PF14038.6 KEZ44580.1 - 5 7.2 5.6 3.3 7.8 0.2 2.8 2 0 0 2 2 2 0 YqzE-like protein CAP59_mtransfer PF11735.8 KEZ44581.1 - 1.4e-72 244.3 0.0 2.3e-72 243.6 0.0 1.4 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CoA_transf_3 PF02515.17 KEZ44582.1 - 2.2e-125 418.6 0.0 3.8e-125 417.8 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.29 KEZ44582.1 - 0.016 15.1 9.0 0.03 14.2 9.0 1.5 1 0 0 1 1 1 0 PHD-finger Cytochrom_CIII PF02085.16 KEZ44582.1 - 0.02 15.2 4.7 0.042 14.2 4.7 1.5 1 0 0 1 1 1 0 Class III cytochrome C family DUF2318 PF10080.9 KEZ44582.1 - 0.048 13.8 0.6 0.12 12.6 0.6 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) C1_1 PF00130.22 KEZ44582.1 - 0.13 12.1 1.2 0.31 11.0 1.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KEZ44582.1 - 0.57 10.5 3.9 0.46 10.8 0.8 2.1 2 0 0 2 2 2 0 C1 domain Glyco_hydro_20 PF00728.22 KEZ44583.1 - 2e-89 300.4 0.0 2.5e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KEZ44583.1 - 4.1e-29 102.0 0.0 7.4e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KEZ44583.1 - 1.1e-06 29.4 0.0 0.0013 19.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 KEZ44584.1 - 4.7e-60 203.6 0.0 9.1e-60 202.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 KEZ44585.1 - 4.6e-18 65.5 0.0 8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KEZ44585.1 - 5.8e-05 22.1 0.0 0.00025 20.0 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HET PF06985.11 KEZ44586.1 - 0.00042 20.7 0.1 0.0013 19.1 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_16 PF00722.21 KEZ44587.1 - 7.8e-45 152.5 1.0 1.2e-44 151.9 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I PF01028.20 KEZ44588.1 - 4.5e-99 330.4 6.8 1.4e-98 328.8 6.8 1.9 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KEZ44588.1 - 1.1e-94 315.8 6.3 1.1e-94 315.8 6.3 3.1 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KEZ44588.1 - 1.6e-29 101.6 0.3 1.6e-29 101.6 0.3 2.7 3 0 0 3 3 3 1 C-terminal topoisomerase domain DWNN PF08783.11 KEZ44588.1 - 0.053 13.8 0.1 0.21 11.9 0.1 2.0 1 0 0 1 1 1 0 DWNN domain ATP-synt PF00231.19 KEZ44589.1 - 9.7e-80 268.3 1.3 1.2e-79 268.0 1.3 1.0 1 0 0 1 1 1 1 ATP synthase EspA PF03433.13 KEZ44589.1 - 0.072 12.9 0.6 2.3 8.1 0.1 2.2 2 1 0 2 2 2 0 EspA-like secreted protein Amino_oxidase PF01593.24 KEZ44590.1 - 5.4e-79 266.6 0.0 6e-78 263.1 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 KEZ44590.1 - 1.8e-13 50.6 0.0 4.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 KEZ44590.1 - 1.8e-06 28.3 4.1 2.1e-06 28.1 2.1 2.3 2 1 0 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 KEZ44590.1 - 6.1e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 KEZ44590.1 - 5e-05 23.8 1.5 0.00012 22.6 1.5 1.6 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 KEZ44590.1 - 0.00042 19.6 0.0 0.0084 15.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ44590.1 - 0.0028 16.8 0.0 0.68 8.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 KEZ44590.1 - 0.005 16.5 0.4 0.011 15.4 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF2057 PF09829.9 KEZ44590.1 - 0.67 10.1 0.0 0.67 10.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) FAD_binding_2 PF00890.24 KEZ44590.1 - 2.2 7.2 8.7 2.1 7.3 2.1 3.4 3 1 0 3 3 3 0 FAD binding domain Sec1 PF00995.23 KEZ44591.1 - 4e-120 402.8 0.0 4.5e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.6 KEZ44592.1 - 3.8e-39 134.8 0.0 9.5e-33 113.8 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KEZ44592.1 - 3.2e-12 46.4 0.0 5.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KEZ44592.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 KEZ44592.1 - 0.00027 21.0 0.0 0.00068 19.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KEZ44592.1 - 0.014 14.5 0.1 0.1 11.7 0.1 2.1 1 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Pkinase PF00069.25 KEZ44594.1 - 6.4e-69 232.3 0.0 8.8e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44594.1 - 3.6e-33 114.9 0.0 5.7e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ44594.1 - 1.9e-05 24.2 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KEZ44594.1 - 0.0057 16.0 0.1 0.015 14.7 0.1 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KEZ44594.1 - 0.028 13.9 0.1 0.24 10.9 0.0 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL UQ_con PF00179.26 KEZ44595.1 - 6.1e-27 94.0 0.0 7.1e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ44595.1 - 1.1e-06 28.4 0.0 3.7e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KEZ44595.1 - 0.0021 17.9 0.1 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KEZ44595.1 - 0.003 17.8 0.1 0.0038 17.5 0.1 1.2 1 0 0 1 1 1 1 RWD domain MFS_1 PF07690.16 KEZ44596.1 - 1e-39 136.5 24.1 1.3e-39 136.1 24.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ44596.1 - 3.5e-12 45.9 9.9 3.5e-12 45.9 9.9 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ44596.1 - 4.6e-10 38.5 2.8 4.6e-10 38.5 2.8 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trp_oprn_chp PF09534.10 KEZ44596.1 - 0.12 12.2 4.4 0.24 11.2 0.1 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) OATP PF03137.20 KEZ44596.1 - 0.47 8.7 6.9 0.31 9.3 2.8 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ABC_membrane PF00664.23 KEZ44597.1 - 2.3e-86 289.8 32.2 7.8e-46 156.9 12.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ44597.1 - 3.7e-64 215.4 0.0 3e-32 112.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ44597.1 - 2.6e-16 59.7 2.4 2.1e-08 33.9 0.2 3.6 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KEZ44597.1 - 1.2e-09 38.8 0.1 0.00021 21.7 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KEZ44597.1 - 1e-07 31.2 0.2 0.021 13.7 0.0 3.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KEZ44597.1 - 1.6e-07 31.4 0.1 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KEZ44597.1 - 2.8e-07 30.2 0.3 0.0017 18.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ44597.1 - 4.8e-07 30.1 0.2 0.094 13.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KEZ44597.1 - 4.9e-06 26.6 0.0 0.048 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KEZ44597.1 - 6.8e-06 26.1 0.1 0.47 10.2 0.0 3.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3987 PF13148.6 KEZ44597.1 - 1.4e-05 24.3 1.2 0.00012 21.3 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) ATP-synt_ab PF00006.25 KEZ44597.1 - 6.4e-05 22.7 0.0 0.23 11.1 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KEZ44597.1 - 0.0003 20.4 0.2 1.3 8.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 KEZ44597.1 - 0.0004 20.2 5.5 0.29 10.8 0.1 3.7 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.6 KEZ44597.1 - 0.0005 20.6 8.0 0.075 13.5 3.4 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KEZ44597.1 - 0.00055 20.5 0.2 0.37 11.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEZ44597.1 - 0.00092 19.2 0.3 3.1 7.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ44597.1 - 0.0014 18.2 0.1 2.3 7.7 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region PRK PF00485.18 KEZ44597.1 - 0.0024 17.7 0.1 0.56 9.9 0.1 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 KEZ44597.1 - 0.0024 18.1 3.0 0.86 9.9 0.3 4.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KEZ44597.1 - 0.0026 18.2 5.6 11 6.4 0.1 4.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 KEZ44597.1 - 0.0059 15.9 0.1 0.42 9.8 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin SRP54 PF00448.22 KEZ44597.1 - 0.012 15.2 0.0 27 4.3 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AP3D1 PF06375.11 KEZ44597.1 - 0.013 15.8 7.8 0.034 14.4 7.8 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 ABC_membrane_3 PF13748.6 KEZ44597.1 - 0.013 14.7 3.1 0.24 10.6 0.1 2.6 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_28 PF13521.6 KEZ44597.1 - 0.023 14.9 0.1 3.5 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KEZ44597.1 - 0.026 14.5 0.5 8.5 6.4 0.1 3.3 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 KEZ44597.1 - 0.027 14.4 0.0 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Gtr1_RagA PF04670.12 KEZ44597.1 - 0.05 13.0 0.0 9.9 5.4 0.0 2.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 KEZ44597.1 - 0.053 13.7 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KEZ44597.1 - 0.069 12.3 0.8 9.3 5.3 0.0 2.5 2 1 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 KEZ44597.1 - 0.072 12.3 0.0 9 5.4 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.17 KEZ44597.1 - 0.11 12.5 0.0 0.95 9.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 KEZ44597.1 - 0.15 12.5 0.0 34 4.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Hydrolase_4 PF12146.8 KEZ44598.1 - 6.3e-15 55.1 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KEZ44598.1 - 3.7e-10 39.9 0.4 5.9e-10 39.2 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ44598.1 - 4.7e-09 37.2 9.1 9.2e-09 36.2 9.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEZ44598.1 - 0.0066 16.2 0.2 0.23 11.2 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 KEZ44598.1 - 0.0077 15.9 0.8 0.014 15.1 0.8 1.5 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 KEZ44598.1 - 0.026 14.1 0.1 0.26 10.8 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KEZ44598.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 KEZ44598.1 - 0.18 11.6 0.0 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family FYVE PF01363.21 KEZ44599.1 - 5.2e-09 36.1 2.1 5.2e-09 36.1 2.1 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KEZ44599.1 - 3.6e-07 30.4 4.9 3.6e-07 30.4 4.9 3.7 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KEZ44599.1 - 0.00016 21.4 4.1 0.00016 21.4 4.1 2.7 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEZ44599.1 - 0.00018 21.3 3.8 0.00018 21.3 3.8 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ44599.1 - 0.0044 17.0 5.0 0.0044 17.0 5.0 3.6 3 0 0 3 3 3 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 KEZ44599.1 - 0.14 12.0 4.2 0.1 12.5 0.5 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING-like PF08746.11 KEZ44599.1 - 1.6 9.1 8.8 0.067 13.5 2.4 2.1 2 0 0 2 2 2 0 RING-like domain zf-C3HC4 PF00097.25 KEZ44599.1 - 2.6 8.0 14.5 0.028 14.3 3.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CarbpepA_inh PF02977.15 KEZ44599.1 - 3.5 7.5 5.7 35 4.3 0.1 3.3 2 1 0 2 2 2 0 Carboxypeptidase A inhibitor zf-C2H2_6 PF13912.6 KEZ44599.1 - 5.2 7.2 7.4 16 5.7 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-rbx1 PF12678.7 KEZ44599.1 - 6 7.2 15.7 0.3 11.4 5.7 3.3 3 1 0 3 3 3 0 RING-H2 zinc finger domain C2 PF00168.30 KEZ44600.1 - 5.7e-88 290.0 0.8 8.7e-26 90.2 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KEZ44600.1 - 2.4e-05 23.9 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 KEZ44600.1 - 0.17 11.6 0.5 5.6 6.7 0.0 3.6 4 1 1 5 5 5 0 N-terminal C2 in EEIG1 and EHBP1 proteins Proteasome PF00227.26 KEZ44601.1 - 2.2e-46 157.8 0.3 2.6e-46 157.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_transf_3 PF00591.21 KEZ44602.1 - 2.7e-61 207.4 0.0 3.8e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KEZ44602.1 - 1.7e-10 40.6 0.0 7.9e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Lip_A_acyltrans PF03279.13 KEZ44602.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Methyltransf_25 PF13649.6 KEZ44603.1 - 0.0011 19.6 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ44603.1 - 0.0063 16.4 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44603.1 - 0.0076 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KEZ44603.1 - 0.014 16.0 0.0 0.023 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 KEZ44604.1 - 8.4e-21 73.4 0.1 9.4e-21 73.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KEZ44604.1 - 0.00012 22.1 0.1 0.00014 21.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KEZ44604.1 - 0.0011 19.1 0.1 0.0012 18.9 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 KEZ44604.1 - 0.13 11.9 0.1 0.21 11.3 0.1 1.4 1 1 0 1 1 1 0 Hfq protein Rad60-SLD PF11976.8 KEZ44605.1 - 1.2e-14 53.8 0.2 2.4e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KEZ44605.1 - 2.6e-05 23.9 0.1 6.4e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family TFA2_Winged_2 PF18121.1 KEZ44606.1 - 0.1 12.3 0.2 0.9 9.3 0.0 2.7 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 APC_N_CC PF16689.5 KEZ44606.1 - 1 9.5 9.2 1.3 9.1 1.4 4.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Filament PF00038.21 KEZ44606.1 - 5.1 6.6 89.1 0.17 11.4 15.9 6.6 3 2 3 7 7 7 0 Intermediate filament protein DivIC PF04977.15 KEZ44606.1 - 7.2 6.5 0.0 7.2 6.5 0.0 10.9 7 4 3 10 10 10 0 Septum formation initiator Ammonium_transp PF00909.21 KEZ44607.1 - 2.4e-119 398.6 28.8 2.8e-119 398.4 28.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 KEZ44607.1 - 2 8.5 5.7 0.69 10.0 1.3 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S Sec10 PF07393.11 KEZ44608.1 - 7.5e-222 738.7 9.1 9.6e-222 738.3 9.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Arg_decarbox_C PF17944.1 KEZ44608.1 - 5.9 7.5 7.8 2.7 8.6 0.1 4.1 5 0 0 5 5 5 0 Arginine decarboxylase C-terminal helical extension Glyco_hydro_18 PF00704.28 KEZ44610.1 - 1.3e-65 222.2 0.2 1.9e-65 221.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEZ44610.1 - 3.2e-10 40.3 6.2 3.2e-10 40.3 6.2 4.0 4 0 0 4 4 4 1 Chitin recognition protein Glyco_hydro_85 PF03644.13 KEZ44610.1 - 0.0017 17.9 0.2 0.0026 17.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 LysM PF01476.20 KEZ44611.1 - 5.8e-14 51.9 0.0 0.00064 19.7 0.0 5.8 6 0 0 6 6 6 4 LysM domain Met_10 PF02475.16 KEZ44613.1 - 7.1e-73 244.6 0.0 1e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KEZ44613.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF1752 PF08550.10 KEZ44614.1 - 6.1e-10 38.8 6.8 1.3e-09 37.7 6.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNB PF00773.19 KEZ44615.1 - 8.8e-44 150.1 0.0 5.6e-43 147.5 0.0 2.1 1 1 0 1 1 1 1 RNB domain DUF3824 PF12868.7 KEZ44616.1 - 0.14 12.8 0.0 0.14 12.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) Diedel PF13164.6 KEZ44616.1 - 0.67 10.4 4.2 3 8.4 0.7 2.7 2 0 0 2 2 2 0 Diedel WD40 PF00400.32 KEZ44617.1 - 0.0012 19.7 0.6 0.0073 17.1 0.6 2.5 1 0 0 1 1 1 1 WD domain, G-beta repeat DUF2415 PF10313.9 KEZ44617.1 - 0.0012 18.7 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Chitin_synth_2 PF03142.15 KEZ44618.1 - 2.4e-291 966.9 0.2 3.2e-291 966.5 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KEZ44618.1 - 4e-15 56.2 1.0 1.1e-14 54.8 1.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KEZ44618.1 - 3.2e-11 43.5 0.0 7.3e-10 39.1 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ44618.1 - 0.00016 21.2 0.0 0.0048 16.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEZ44618.1 - 0.0061 16.4 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1418 PF07214.12 KEZ44618.1 - 2.3 8.1 6.5 11 5.9 6.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Sel1 PF08238.12 KEZ44619.1 - 5.9e-36 122.1 30.9 4e-05 24.1 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 KEZ44619.1 - 0.14 12.9 1.0 8.8 7.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KEZ44620.1 - 9.1e-69 231.7 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44620.1 - 1.8e-41 142.1 0.0 2.8e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KEZ44620.1 - 1.4e-06 28.4 0.0 0.00071 19.7 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KEZ44620.1 - 3.8e-05 23.2 0.1 9.1e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEZ44620.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ44620.1 - 0.056 12.2 0.1 0.14 10.9 0.1 1.6 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KEZ44620.1 - 0.21 10.5 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain OPA3 PF07047.12 KEZ44621.1 - 3.8e-42 143.0 0.1 3.8e-42 143.0 0.1 1.7 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) SBDS PF01172.18 KEZ44621.1 - 6.4e-20 71.0 0.1 1.2e-19 70.2 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein VSG_B PF13206.6 KEZ44621.1 - 0.0017 17.6 0.8 0.0027 17.0 0.8 1.2 1 0 0 1 1 1 1 Trypanosomal VSG domain TRPM_tetra PF16519.5 KEZ44621.1 - 0.02 15.0 3.0 0.044 13.9 3.0 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM RhoGEF PF00621.20 KEZ44623.1 - 9.8e-24 84.6 0.1 1.5e-23 84.0 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.20 KEZ44624.1 - 2.9e-49 167.0 4.8 6.2e-49 166.0 2.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEZ44624.1 - 1.2e-46 158.7 4.1 1.2e-46 158.7 4.1 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KEZ44624.1 - 1.2e-21 76.5 0.0 2.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ44624.1 - 5.1e-21 75.9 0.1 8.2e-17 62.2 0.0 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ44624.1 - 1.2e-18 66.5 0.0 3.6e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ44624.1 - 3.1e-07 30.4 1.0 1.1e-05 25.3 0.9 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ44624.1 - 0.00011 22.6 0.0 0.00073 20.0 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Proteasome PF00227.26 KEZ44625.1 - 9.7e-40 136.1 0.0 1.2e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 KEZ44626.1 - 2.5e-24 85.3 0.1 2e-23 82.3 0.0 2.4 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 KEZ44626.1 - 0.06 13.6 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 UBX domain CLU PF13236.6 KEZ44626.1 - 0.096 12.5 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Clustered mitochondria RBD PF02196.15 KEZ44626.1 - 0.12 12.5 0.2 2.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Raf-like Ras-binding domain Ribosomal_L36e PF01158.18 KEZ44627.1 - 4.1e-41 139.1 5.8 4.6e-41 139.0 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 KEZ44627.1 - 0.02 14.9 0.2 0.024 14.7 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide MRP-L28 PF09812.9 KEZ44627.1 - 0.069 13.3 2.3 0.079 13.1 2.0 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 LemA PF04011.12 KEZ44627.1 - 0.096 12.5 0.4 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 LemA family PRA-PH PF01503.17 KEZ44627.1 - 0.11 12.9 0.1 0.48 10.9 0.1 1.9 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF2207 PF09972.9 KEZ44627.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AltA1 PF16541.5 KEZ44628.1 - 0.0084 17.0 1.3 0.012 16.5 1.3 1.2 1 0 0 1 1 1 1 Alternaria alternata allergen 1 14-3-3 PF00244.20 KEZ44629.1 - 1e-107 358.7 3.1 1.2e-107 358.5 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaC_arch PF05377.11 KEZ44629.1 - 0.24 11.8 1.2 0.57 10.6 1.2 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Syja_N PF02383.18 KEZ44630.1 - 1.8e-71 241.1 0.0 3.5e-71 240.1 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 KEZ44630.1 - 2.1e-09 37.3 0.1 4.2e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Uso1_p115_C PF04871.13 KEZ44630.1 - 0.65 10.4 1.8 1.3 9.4 1.8 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_14 PF13428.6 KEZ44631.1 - 6e-06 26.6 9.9 0.1 13.5 0.2 7.2 4 3 5 9 9 9 2 Tetratricopeptide repeat Suf PF05843.14 KEZ44631.1 - 0.00014 22.0 6.3 0.08 12.9 0.0 3.3 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) EF-1_beta_acid PF10587.9 KEZ44631.1 - 0.12 12.8 0.2 0.5 10.8 0.2 2.1 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region peroxidase PF00141.23 KEZ44632.1 - 2.2e-48 165.0 0.0 3.5e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Homeodomain PF00046.29 KEZ44633.1 - 9.5e-14 51.0 3.2 2.3e-13 49.7 3.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KEZ44633.1 - 0.0037 17.2 0.4 0.0096 15.8 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Dna2 PF08696.11 KEZ44633.1 - 0.11 12.3 1.9 0.19 11.5 1.9 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 Auxin_canalis PF05703.11 KEZ44633.1 - 7.1 6.5 15.3 0.019 14.9 4.3 2.2 3 0 0 3 3 3 0 Auxin canalisation HAD_2 PF13419.6 KEZ44634.1 - 1.2e-17 64.6 0.0 1.6e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KEZ44634.1 - 6.4e-07 29.9 0.0 0.035 14.4 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ44634.1 - 5.1e-05 23.2 0.0 8.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like GHL6 PF14871.6 KEZ44634.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 HAD PF12710.7 KEZ44634.1 - 0.19 12.1 0.0 0.33 11.4 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.11 KEZ44635.1 - 1e-25 89.6 18.5 2e-25 88.7 18.5 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KEZ44635.1 - 7.8e-16 58.2 0.0 1.4e-11 44.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ44635.1 - 2.1e-08 34.3 0.0 4.3e-07 30.0 0.0 2.2 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KEZ44635.1 - 8.8e-07 28.6 0.0 0.022 14.3 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KEZ44635.1 - 6.9e-05 23.0 0.7 0.15 12.1 0.1 3.6 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 KEZ44635.1 - 0.0014 18.2 0.1 0.079 12.5 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 KEZ44635.1 - 0.026 14.1 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KEZ44635.1 - 0.042 12.8 0.1 0.042 12.8 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nuc_deoxyri_tr2 PF15891.5 KEZ44635.1 - 0.17 12.2 0.3 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like AAA_16 PF13191.6 KEZ44635.1 - 0.2 12.1 10.3 0.25 11.7 0.1 3.3 2 1 0 2 2 2 0 AAA ATPase domain UPF0767 PF15990.5 KEZ44635.1 - 6.3 7.0 6.2 19 5.5 0.0 3.1 3 0 0 3 3 3 0 UPF0767 family RNB PF00773.19 KEZ44636.1 - 6.4e-98 328.1 0.2 9.7e-98 327.5 0.2 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KEZ44636.1 - 8.6e-31 105.8 0.1 3.4e-30 103.8 0.1 2.1 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KEZ44636.1 - 4.9e-30 104.2 0.1 1.5e-29 102.6 0.1 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KEZ44636.1 - 7.1e-18 64.4 0.0 2.5e-17 62.7 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KEZ44636.1 - 5.6e-12 46.1 0.3 5.6e-12 46.1 0.3 2.6 3 0 0 3 3 3 1 PIN domain CSD2 PF17876.1 KEZ44636.1 - 1.8e-05 24.8 0.0 0.028 14.6 0.0 3.0 3 0 0 3 3 3 2 Cold shock domain Dis3l2_C_term PF17877.1 KEZ44636.1 - 0.017 15.4 0.0 0.065 13.6 0.0 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal CRC_subunit PF08624.10 KEZ44637.1 - 1.4e-52 177.7 0.0 2e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 KEZ44638.1 - 4.3e-09 36.5 0.0 7.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEZ44638.1 - 7.8e-06 26.3 0.3 7.8e-06 26.3 0.3 2.5 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KEZ44638.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KEZ44638.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CDC27 PF09507.10 KEZ44638.1 - 0.4 10.0 39.2 0.091 12.1 22.5 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Mid2 PF04478.12 KEZ44639.1 - 0.069 13.0 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Gemini_mov PF01708.16 KEZ44639.1 - 2 8.3 0.0 2 8.3 0.0 2.9 2 0 0 2 2 2 0 Geminivirus putative movement protein G6PD_C PF02781.16 KEZ44640.1 - 1.9e-115 385.0 0.0 3e-115 384.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KEZ44640.1 - 9.8e-60 202.2 0.0 1.7e-59 201.4 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain AMP-binding PF00501.28 KEZ44641.1 - 4.3e-99 332.0 0.0 5.5e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ44641.1 - 4.7e-12 46.7 0.0 1.2e-11 45.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SLD3 PF08639.10 KEZ44642.1 - 1.1e-154 516.2 3.4 1.1e-154 516.2 3.4 1.7 2 0 0 2 2 2 1 DNA replication regulator SLD3 Trs65 PF12735.7 KEZ44643.1 - 5.4e-117 390.7 0.0 7.2e-117 390.3 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.19 KEZ44644.1 - 1.1e-50 169.6 12.2 1.1e-14 54.3 0.0 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.26 KEZ44644.1 - 2.5e-17 62.6 18.0 1.1e-09 38.2 3.3 2.7 2 0 0 2 2 2 2 WW domain HycH PF07450.11 KEZ44644.1 - 0.098 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Glyco_hyd_101C PF17451.2 KEZ44644.1 - 0.21 11.9 5.5 6.5 7.1 0.1 3.0 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain ABC_tran PF00005.27 KEZ44645.1 - 8.7e-33 113.7 0.0 1.2e-15 58.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KEZ44645.1 - 2.3e-13 49.7 5.8 2.3e-13 49.7 5.8 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KEZ44645.1 - 7.6e-10 38.6 2.0 0.0026 17.2 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ44645.1 - 1.2e-09 38.4 5.7 0.19 11.5 1.7 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ44645.1 - 3e-06 27.7 0.0 0.031 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KEZ44645.1 - 1.5e-05 25.2 0.0 0.0031 17.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KEZ44645.1 - 1.6e-05 25.3 0.0 0.022 15.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KEZ44645.1 - 2.6e-05 24.1 0.2 0.2 11.3 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain Fer4 PF00037.27 KEZ44645.1 - 0.0002 21.0 4.1 0.0002 21.0 4.1 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 KEZ44645.1 - 0.00022 21.2 0.1 0.76 9.7 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 KEZ44645.1 - 0.00027 21.5 0.0 0.075 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEZ44645.1 - 0.00035 20.9 0.0 0.2 12.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Rad17 PF03215.15 KEZ44645.1 - 0.00041 20.3 0.1 0.067 13.1 0.0 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain Fer4_10 PF13237.6 KEZ44645.1 - 0.00049 20.2 9.0 0.014 15.5 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.6 KEZ44645.1 - 0.00049 20.6 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KEZ44645.1 - 0.00095 18.9 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KEZ44645.1 - 0.0011 18.7 0.4 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 KEZ44645.1 - 0.0011 18.6 1.4 0.09 12.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_21 PF14697.6 KEZ44645.1 - 0.0019 18.3 11.4 0.0037 17.4 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.12 KEZ44645.1 - 0.0023 17.9 1.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 KEZ44645.1 - 0.0025 17.5 0.2 2.5 7.7 0.0 2.9 3 0 0 3 3 3 1 Thymidylate kinase AAA_33 PF13671.6 KEZ44645.1 - 0.0035 17.5 0.0 0.55 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 KEZ44645.1 - 0.0042 15.8 0.5 0.0088 14.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KEZ44645.1 - 0.0044 17.0 0.2 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_6 PF12837.7 KEZ44645.1 - 0.0047 16.9 13.9 0.0057 16.7 2.9 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_5 PF07728.14 KEZ44645.1 - 0.0066 16.4 0.6 0.25 11.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ44645.1 - 0.0076 15.8 0.6 0.097 12.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_7 PF12838.7 KEZ44645.1 - 0.012 16.2 7.7 0.012 16.2 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_28 PF13521.6 KEZ44645.1 - 0.016 15.5 0.2 2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KEZ44645.1 - 0.024 13.8 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Fer4_9 PF13187.6 KEZ44645.1 - 0.038 14.2 10.5 0.083 13.1 10.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 KEZ44645.1 - 0.043 13.5 0.3 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KEZ44645.1 - 0.046 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Fer4_16 PF13484.6 KEZ44645.1 - 0.055 14.4 0.2 0.055 14.4 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 KEZ44645.1 - 0.11 12.6 0.4 15 5.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KEZ44645.1 - 0.13 12.3 0.2 13 5.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain VirE PF05272.11 KEZ44645.1 - 0.14 11.9 0.0 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_17 PF13534.6 KEZ44645.1 - 0.14 12.7 0.1 0.14 12.7 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 KEZ44645.1 - 0.21 11.5 1.4 6.6 6.6 0.0 2.6 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 KEZ44645.1 - 0.29 10.9 0.7 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 KEZ44645.1 - 0.36 10.6 2.1 0.61 9.8 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.6 KEZ44645.1 - 6.6 7.3 10.7 0.87 10.1 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 KEZ44645.1 - 7.4 6.9 11.4 0.66 10.2 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 KEZ44646.1 - 3.4e-53 180.6 0.0 5.5e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KEZ44646.1 - 1.5e-27 95.2 4.4 3.2e-17 62.2 0.5 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KEZ44646.1 - 3.2e-19 69.3 0.0 7.4e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 KEZ44646.1 - 5.1e-15 55.7 0.0 1.8e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 KEZ44646.1 - 3.9e-09 36.1 0.1 1.2e-08 34.5 0.1 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 KEZ44646.1 - 5.4e-06 26.7 17.7 8.5e-05 22.9 0.5 4.3 2 1 1 3 3 3 2 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 KEZ44646.1 - 1.7e-05 25.4 3.7 1.7e-05 25.4 3.7 3.3 3 0 0 3 3 2 1 CDH1/2 SANT-Helical linker 1 ResIII PF04851.15 KEZ44646.1 - 3.6e-05 23.8 0.0 0.0003 20.8 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 KEZ44646.1 - 6.2e-05 23.0 0.1 0.0017 18.4 0.0 3.2 2 0 0 2 2 2 1 SLIDE Myb_DNA-binding PF00249.31 KEZ44646.1 - 0.0066 16.6 0.0 0.16 12.2 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 KEZ44646.1 - 0.027 14.6 0.0 0.027 14.6 0.0 2.9 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain AAA_22 PF13401.6 KEZ44646.1 - 0.071 13.4 0.0 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Med16 PF11635.8 KEZ44647.1 - 1.4e-82 277.9 0.0 1.8e-82 277.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Helicase_C_4 PF13871.6 KEZ44647.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue zf-CCCH_2 PF14608.6 KEZ44648.1 - 4.3e-12 46.0 51.8 1.6e-05 25.2 11.3 5.5 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KEZ44648.1 - 0.0075 16.5 0.1 0.017 15.4 0.0 1.6 2 0 0 2 2 2 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) TFIIA PF03153.13 KEZ44648.1 - 9.1 6.2 12.5 13 5.7 12.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Amino_oxidase PF01593.24 KEZ44649.1 - 6.6e-29 101.5 0.0 8.2e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ44649.1 - 1e-12 48.0 0.2 5.9e-12 45.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ44649.1 - 7.4e-10 38.9 0.0 2.5e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ44649.1 - 1.2e-05 24.8 0.1 0.00051 19.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ44649.1 - 0.0032 18.0 2.8 0.032 14.8 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ44649.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KEZ44649.1 - 0.028 13.3 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 KEZ44649.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 KEZ44649.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Ribul_P_3_epim PF00834.19 KEZ44649.1 - 0.24 10.7 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Med14 PF08638.11 KEZ44650.1 - 7.8e-59 198.3 0.0 1.6e-58 197.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Ribosomal_L35Ae PF01247.18 KEZ44651.1 - 5.1e-41 138.8 0.2 5.7e-41 138.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KEZ44651.1 - 0.00021 21.4 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.9 KEZ44652.1 - 1.3e-16 61.0 0.2 2.9e-16 59.9 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 KEZ44653.1 - 6.4e-15 55.0 8.2 9e-15 54.5 8.2 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 KEZ44654.1 - 7.8e-50 169.5 0.0 1.3e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ44654.1 - 8.4e-17 61.5 0.0 2.4e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KEZ44654.1 - 0.00019 20.7 0.0 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RTT107_BRCT_5 PF16770.5 KEZ44654.1 - 0.02 14.7 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain HIGH_NTase1_ass PF16581.5 KEZ44654.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region DUF3602 PF12223.8 KEZ44655.1 - 1e-22 80.5 5.4 1e-22 80.5 5.4 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Glyco_hydro_10 PF00331.20 KEZ44656.1 - 1.4e-100 336.5 1.9 1.6e-100 336.3 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 zf-CCCH PF00642.24 KEZ44657.1 - 5.1e-11 42.2 8.4 1.5e-05 24.7 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KEZ44657.1 - 1.9e-10 40.3 11.8 2.7e-05 23.9 3.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KEZ44657.1 - 4.6e-10 39.2 17.4 7.2e-05 22.7 4.2 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KEZ44657.1 - 5.1e-09 36.8 6.0 7.4e-05 23.4 0.4 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 KEZ44657.1 - 5.1e-05 23.5 1.5 9.1e-05 22.6 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KEZ44657.1 - 0.0039 17.6 17.2 0.081 13.4 5.4 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger PP-binding PF00550.25 KEZ44658.1 - 2.4e-12 47.0 0.1 3.2e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KEZ44658.1 - 0.00028 21.0 0.1 0.00041 20.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.27 KEZ44659.1 - 4.3e-14 51.7 16.4 5.7e-08 32.2 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KEZ44659.1 - 5.1e-13 49.4 10.7 8.6e-13 48.7 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KEZ44659.1 - 7.3e-11 42.8 7.2 7.5e-05 23.6 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KEZ44659.1 - 3.6e-10 39.8 4.7 7.3e-05 22.8 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KEZ44659.1 - 5.5e-09 36.0 21.6 1e-06 28.7 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KEZ44659.1 - 2e-08 34.3 10.1 4e-08 33.3 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ44659.1 - 3.4e-07 30.6 19.9 0.00014 22.3 11.9 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 KEZ44659.1 - 7.7e-07 28.9 16.9 0.0002 21.3 5.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KEZ44659.1 - 9.6e-07 28.5 12.2 0.0027 17.7 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KEZ44659.1 - 2e-05 24.7 11.6 0.00065 20.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KEZ44659.1 - 6.5e-05 23.4 11.3 0.015 15.8 12.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KEZ44659.1 - 0.005 17.0 5.5 0.58 10.4 0.4 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KEZ44659.1 - 0.031 14.5 9.3 0.5 10.6 1.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KEZ44659.1 - 0.045 13.9 4.9 0.23 11.6 0.3 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 KEZ44659.1 - 0.063 13.8 14.6 0.8 10.3 4.0 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KEZ44659.1 - 0.085 13.8 16.6 0.4 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KEZ44659.1 - 0.38 11.6 11.8 3.1 8.7 2.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain EPF PF17181.4 KEZ44659.1 - 0.4 10.7 5.8 0.17 11.9 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Mito_carr PF00153.27 KEZ44660.1 - 2.9e-52 174.5 3.0 1.6e-21 76.1 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.9 KEZ44662.1 - 4.7e-85 284.8 0.0 9.5e-85 283.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) TMEM252 PF15664.5 KEZ44662.1 - 0.011 15.5 0.2 3.9 7.2 0.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 252 family PCMT PF01135.19 KEZ44663.1 - 8.8e-59 198.8 0.0 1.2e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEZ44663.1 - 4.8e-06 26.4 0.0 8.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KEZ44663.1 - 4.9e-05 23.4 0.0 7.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44663.1 - 0.00058 20.5 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ44663.1 - 0.0027 17.6 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44663.1 - 0.0035 16.7 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 KEZ44663.1 - 0.0072 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.12 KEZ44663.1 - 0.018 15.7 0.0 0.048 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DAGK_prokar PF01219.19 KEZ44663.1 - 0.049 13.5 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase MTS PF05175.14 KEZ44663.1 - 0.053 13.1 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 KEZ44663.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 KEZ44663.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.17 KEZ44663.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_16 PF10294.9 KEZ44663.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase GMC_oxred_N PF00732.19 KEZ44664.1 - 5.8e-47 160.5 0.0 8e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ44664.1 - 1e-29 103.9 0.0 1.9e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KEZ44664.1 - 0.0047 16.2 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KEZ44664.1 - 0.011 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 KEZ44664.1 - 0.017 15.4 0.2 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 KEZ44664.1 - 0.031 13.9 0.2 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ44664.1 - 0.04 14.1 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ44664.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ44664.1 - 0.18 10.8 0.1 0.36 9.8 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain GRIM-19 PF06212.12 KEZ44665.1 - 2.5e-22 79.3 0.0 2.7e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein GldH_lipo PF14109.6 KEZ44665.1 - 0.064 14.0 0.0 0.085 13.6 0.0 1.1 1 0 0 1 1 1 0 GldH lipoprotein Cnd1_N PF12922.7 KEZ44666.1 - 3.2e-62 209.3 0.7 9.3e-61 204.5 0.2 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KEZ44666.1 - 1.1e-46 158.8 6.2 4.2e-44 150.4 0.3 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KEZ44666.1 - 4.5e-10 38.9 1.5 0.12 12.7 0.0 6.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KEZ44666.1 - 1.4e-07 31.8 2.2 0.0049 17.2 0.0 5.0 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KEZ44666.1 - 0.00045 20.7 4.2 0.1 13.1 0.1 4.8 4 1 0 4 4 4 1 HEAT-like repeat RTP1_C1 PF10363.9 KEZ44666.1 - 0.001 19.2 0.1 3.3 7.9 0.0 3.7 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KEZ44666.1 - 0.0021 17.3 0.5 0.0021 17.3 0.5 3.3 3 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Spore_GerAC PF05504.11 KEZ44666.1 - 0.12 12.5 0.3 0.36 11.1 0.3 1.7 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Pkinase PF00069.25 KEZ44667.1 - 2.1e-42 145.4 0.0 4.6e-39 134.4 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44667.1 - 8.8e-14 51.4 0.0 1.1e-07 31.4 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KEZ44667.1 - 0.00022 21.3 0.0 0.045 13.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ44667.1 - 0.0014 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEZ44667.1 - 0.0038 16.6 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KEZ44667.1 - 0.12 11.7 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L27A PF00828.19 KEZ44668.1 - 1.4e-11 45.2 0.5 2.4e-11 44.4 0.5 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Helicase_C_2 PF13307.6 KEZ44670.1 - 2.7e-58 196.9 0.0 1.3e-57 194.8 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KEZ44670.1 - 1.1e-49 168.4 0.0 1.9e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 AAR2 PF05282.11 KEZ44670.1 - 0.00063 19.3 1.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 1 AAR2 protein ResIII PF04851.15 KEZ44670.1 - 0.0028 17.7 0.0 2.1 8.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEZ44670.1 - 0.17 12.2 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain GRAM PF02893.20 KEZ44671.1 - 3.5e-33 113.9 3.2 4.9e-21 74.8 0.1 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KEZ44671.1 - 2.8e-29 101.9 0.0 6.1e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KEZ44671.1 - 3.9e-15 56.2 0.1 1.2e-14 54.7 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KEZ44671.1 - 2e-07 31.2 0.3 9.1e-07 29.1 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KEZ44671.1 - 2e-06 28.2 1.3 1.3e-05 25.5 1.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KEZ44671.1 - 8.2e-05 22.7 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 KEZ44671.1 - 0.0002 20.3 0.5 0.00033 19.6 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_2 PF08458.10 KEZ44671.1 - 0.0081 16.5 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Plant pleckstrin homology-like region PH_6 PF15406.6 KEZ44671.1 - 0.047 14.0 0.1 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.32 KEZ44672.1 - 5e-09 36.6 9.0 0.044 14.7 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat RTA1 PF04479.13 KEZ44673.1 - 7.9e-46 156.3 0.8 1e-45 155.9 0.8 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.6 KEZ44673.1 - 3.3 7.3 5.9 12 5.5 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Inp1 PF12634.7 KEZ44674.1 - 2.1e-42 144.4 0.1 1.1e-41 142.0 0.0 2.4 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 KEZ44675.1 - 3e-12 47.1 17.3 9e-08 32.6 3.5 2.1 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Zn_clus PF00172.18 KEZ44676.1 - 2.1e-09 37.4 11.3 3.4e-09 36.7 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ44676.1 - 0.00022 20.3 0.0 0.00047 19.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TERB2 PF15101.6 KEZ44676.1 - 1 9.4 9.3 1.9 8.5 9.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Roughex PF06020.11 KEZ44676.1 - 3.3 6.7 6.3 6.1 5.8 6.3 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 KEZ44676.1 - 6.5 6.6 20.5 12 5.7 20.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bromodomain PF00439.25 KEZ44677.1 - 1.4e-37 127.6 0.1 8.4e-20 70.6 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KEZ44677.1 - 4.2e-18 65.3 0.1 1.5e-17 63.6 0.1 2.0 1 0 0 1 1 1 1 BAH domain DUF913 PF06025.12 KEZ44677.1 - 0.018 14.1 8.0 3.5 6.5 2.3 3.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) DUF2849 PF11011.8 KEZ44677.1 - 1.1 9.9 6.2 1.2 9.8 3.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) DUF2052 PF09747.9 KEZ44677.1 - 1.9 8.6 28.7 0.16 12.1 2.5 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 KEZ44677.1 - 2.7 6.2 27.9 0.026 12.8 3.8 3.1 3 0 0 3 3 3 0 CDC45-like protein zf-C2H2 PF00096.26 KEZ44678.1 - 0.042 14.3 3.7 0.37 11.3 3.7 2.4 1 1 0 1 1 1 0 Zinc finger, C2H2 type TPMT PF05724.11 KEZ44679.1 - 5.2e-27 94.9 0.0 9.6e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) adh_short PF00106.25 KEZ44679.1 - 1.1e-18 67.4 0.0 1.9e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ44679.1 - 8.2e-12 45.2 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 KEZ44679.1 - 2e-07 31.0 0.0 4.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44679.1 - 4.9e-07 30.4 0.0 1.5e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44679.1 - 1.6e-06 28.8 0.1 0.00011 22.8 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Metallophos PF00149.28 KEZ44679.1 - 1.6e-06 28.8 1.3 3.1e-06 27.8 1.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_11 PF08241.12 KEZ44679.1 - 1.1e-05 26.0 0.0 4.6e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KEZ44679.1 - 2e-05 24.6 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_31 PF13847.6 KEZ44679.1 - 2.5e-05 24.1 0.0 0.28 11.0 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Ank_2 PF12796.7 KEZ44680.1 - 1e-11 45.3 0.1 2.3e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ44680.1 - 1.5e-09 37.3 0.1 0.0003 21.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KEZ44680.1 - 4.3e-08 33.3 0.1 5.4e-05 23.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ44680.1 - 4.8e-07 30.2 0.3 3.5e-05 24.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KEZ44680.1 - 5.3e-06 26.6 0.0 0.017 15.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat HTH_Tnp_Tc5 PF03221.16 KEZ44680.1 - 0.00011 22.1 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Aspzincin_M35 PF14521.6 KEZ44680.1 - 0.0016 19.0 0.1 0.0077 16.8 0.0 2.2 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Nodulin_late PF07127.11 KEZ44680.1 - 0.17 12.2 6.2 0.072 13.4 1.4 2.4 2 0 0 2 2 2 0 Late nodulin protein adh_short PF00106.25 KEZ44682.1 - 3.2e-27 95.3 0.0 4.4e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ44682.1 - 1.2e-20 74.1 0.0 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AA_permease_2 PF13520.6 KEZ44683.1 - 2.6e-56 191.3 60.4 3.2e-56 191.0 60.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ44683.1 - 3e-22 78.9 54.4 4e-22 78.5 54.4 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KEZ44684.1 - 3.9e-29 101.6 1.8 5.1e-29 101.3 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ44684.1 - 1.3e-07 31.6 10.7 2.4e-07 30.7 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KEZ44685.1 - 3e-53 181.1 0.0 3.9e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ44685.1 - 2.3e-37 128.7 0.0 3.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KEZ44685.1 - 0.00073 19.7 0.5 0.0028 17.8 0.2 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ44685.1 - 0.0016 17.6 0.1 0.0023 17.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KEZ44685.1 - 0.0096 15.5 1.5 0.15 11.6 0.6 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ44685.1 - 0.025 13.6 0.3 0.72 8.9 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KEZ44685.1 - 0.039 13.2 0.2 0.28 10.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ44685.1 - 0.051 12.4 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AA_permease_2 PF13520.6 KEZ44686.1 - 8.5e-31 107.2 45.3 3e-28 98.8 39.2 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 KEZ44686.1 - 4.7e-12 45.3 29.6 4.7e-12 45.3 29.6 2.1 1 1 0 2 2 2 2 Amino acid permease Peptidase_S8 PF00082.22 KEZ44687.1 - 5.7e-40 137.4 0.0 1.1e-39 136.5 0.0 1.4 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KEZ44687.1 - 4.3e-21 75.7 0.4 1e-20 74.5 0.5 1.7 2 0 0 2 2 2 1 Fn3-like domain FlgD_ig PF13860.6 KEZ44687.1 - 0.03 14.2 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 FlgD Ig-like domain Transport_MerF PF11431.8 KEZ44688.1 - 0.7 9.8 5.9 0.17 11.8 0.6 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF Amino_oxidase PF01593.24 KEZ44689.1 - 2.9e-44 152.1 0.0 5.3e-44 151.2 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ44689.1 - 1.7e-11 44.1 0.3 6e-11 42.4 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KEZ44689.1 - 0.00026 20.5 0.0 0.00061 19.2 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KEZ44689.1 - 0.0023 17.6 3.4 0.0065 16.1 2.4 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ44689.1 - 0.009 15.1 0.3 0.019 14.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ44689.1 - 0.0098 14.6 0.2 0.017 13.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KEZ44689.1 - 0.01 15.1 1.2 0.017 14.4 1.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KEZ44689.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ44689.1 - 0.044 14.3 0.1 0.1 13.2 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KEZ44689.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 KEZ44689.1 - 0.078 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Methyltransf_23 PF13489.6 KEZ44690.1 - 2.6e-18 66.4 0.0 3.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44690.1 - 3.9e-13 49.9 0.0 8.5e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44690.1 - 4e-11 43.4 0.0 7.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44690.1 - 1.7e-08 34.4 0.0 2.3e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44690.1 - 3.1e-07 31.0 0.0 1.2e-06 29.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ44690.1 - 1.1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KEZ44690.1 - 1.6e-05 24.3 0.0 0.00017 21.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEZ44690.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 KEZ44690.1 - 0.043 13.6 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 KEZ44690.1 - 0.045 13.1 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KEZ44690.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KEZ44690.1 - 0.23 10.9 0.0 0.55 9.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Sugar_tr PF00083.24 KEZ44691.1 - 7e-109 364.7 24.1 8.4e-109 364.4 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ44691.1 - 5.9e-23 81.4 32.0 2.7e-15 56.2 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4246 PF14033.6 KEZ44692.1 - 1.3e-163 545.4 0.0 1.5e-163 545.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KEZ44692.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-Fe_Oxy_2 PF10014.9 KEZ44692.1 - 0.034 13.9 0.0 0.19 11.5 0.0 2.2 2 1 0 2 2 2 0 2OG-Fe dioxygenase RXT2_N PF08595.11 KEZ44692.1 - 0.19 11.7 4.0 0.4 10.7 4.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 KEZ44692.1 - 2.2 6.4 5.8 3.6 5.7 5.8 1.3 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_1d PF00750.19 KEZ44693.1 - 6.7e-60 202.9 0.0 1.5e-59 201.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KEZ44693.1 - 2.4e-10 40.6 0.0 5.1e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain AAA PF00004.29 KEZ44694.1 - 3.8e-11 43.5 0.0 7.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HNH_2 PF13391.6 KEZ44696.1 - 2.2e-06 27.7 0.1 8.6e-06 25.8 0.1 2.0 1 1 1 2 2 2 1 HNH endonuclease zf-CCCH_4 PF18044.1 KEZ44697.1 - 0.018 14.9 1.2 0.018 14.9 1.2 4.0 4 1 0 4 4 4 0 CCCH-type zinc finger DUF3173 PF11372.8 KEZ44697.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) zf-CCCH_2 PF14608.6 KEZ44697.1 - 1.2 9.7 14.6 4.2 8.0 0.7 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger CFEM PF05730.11 KEZ44699.1 - 6e-07 29.5 5.9 8.7e-07 28.9 5.9 1.2 1 0 0 1 1 1 1 CFEM domain HNH_2 PF13391.6 KEZ44700.1 - 4.7e-15 55.5 0.1 9.8e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Alk_phosphatase PF00245.20 KEZ44700.1 - 0.055 12.4 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Alkaline phosphatase Med18 PF09637.10 KEZ44701.1 - 5.9e-22 78.7 0.0 7.1e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 KEZ44702.1 - 5.3e-56 188.8 0.0 7.6e-56 188.3 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KEZ44702.1 - 1.2e-24 87.0 0.0 5.4e-22 78.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEZ44702.1 - 5.4e-06 26.1 0.0 0.016 14.7 0.0 2.5 2 1 1 3 3 3 2 Chromatin associated protein KTI12 AAA_22 PF13401.6 KEZ44702.1 - 0.0026 18.0 0.0 0.0065 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KEZ44702.1 - 0.035 14.0 0.0 0.15 12.0 0.0 2.0 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 KEZ44702.1 - 0.1 13.1 0.0 0.42 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 KEZ44702.1 - 0.13 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KEZ44702.1 - 0.13 12.6 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase S36_mt PF10937.8 KEZ44703.1 - 3.1e-41 141.6 0.4 3.7e-41 141.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial CDH-cyt PF16010.5 KEZ44704.1 - 4.5e-44 150.3 5.5 5.6e-44 150.0 5.5 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KEZ44704.1 - 0.00032 20.9 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 DOMON domain ALO PF04030.14 KEZ44705.1 - 8.4e-08 32.3 0.1 6.2e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KEZ44705.1 - 1.1e-07 31.7 0.1 7.1e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Chol_subst-bind PF09129.11 KEZ44705.1 - 0.075 12.0 2.8 2 7.3 0.1 3.1 2 1 0 2 2 2 0 Cholesterol oxidase, substrate-binding Rxt3 PF08642.10 KEZ44706.1 - 1.8e-45 154.8 0.0 6.2e-45 153.1 0.0 2.0 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KEZ44706.1 - 0.0001 22.3 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 2 LCCL domain NicO PF03824.16 KEZ44706.1 - 7.7 5.8 7.1 44 3.3 7.8 1.7 2 0 0 2 2 2 0 High-affinity nickel-transport protein SDF PF00375.18 KEZ44708.1 - 7.3e-90 301.8 33.1 9e-90 301.5 33.1 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.6 KEZ44708.1 - 0.0043 16.8 1.0 0.018 14.8 0.4 2.4 1 1 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MAP17 PF15807.5 KEZ44708.1 - 0.75 10.0 2.3 8.1 6.7 1.3 2.6 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 MDD_C PF18376.1 KEZ44709.1 - 5.3e-60 202.4 0.0 7.9e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KEZ44709.1 - 6.1e-09 36.0 0.8 1.6e-08 34.7 0.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF647 PF04884.14 KEZ44710.1 - 1e-85 287.3 0.4 1.4e-85 286.8 0.4 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.17 KEZ44711.1 - 1.6e-41 142.8 6.4 2.1e-40 139.2 6.4 2.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Acetyltransf_8 PF13523.6 KEZ44711.1 - 6.3e-34 116.7 0.0 1.1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CTP_transf_like PF01467.26 KEZ44712.1 - 1.4e-06 28.6 0.0 3.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like PHO4 PF01384.20 KEZ44713.1 - 1.1e-109 366.6 15.2 1.4e-109 366.2 15.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family SPX PF03105.19 KEZ44714.1 - 1.3e-35 124.1 1.2 4.5e-26 92.7 0.2 4.0 3 1 1 4 4 4 2 SPX domain PPTA PF01239.22 KEZ44714.1 - 5e-31 105.5 11.8 2.4e-07 30.3 1.4 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Na_sulph_symp PF00939.19 KEZ44714.1 - 1.7e-29 103.2 37.5 2.6e-29 102.6 37.5 1.4 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KEZ44714.1 - 5.9e-22 78.2 66.1 1e-20 74.2 42.9 2.5 1 1 1 3 3 3 2 Citrate transporter RFX_DNA_binding PF02257.15 KEZ44714.1 - 0.12 13.0 0.1 0.47 11.1 0.1 1.9 2 0 0 2 2 2 0 RFX DNA-binding domain DUF5392 PF17370.2 KEZ44714.1 - 0.87 9.7 3.8 0.86 9.7 0.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5392) ABC_membrane PF00664.23 KEZ44715.1 - 2.2e-88 296.5 26.3 3.9e-48 164.5 7.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ44715.1 - 2.8e-65 219.0 0.0 9.2e-32 110.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ44715.1 - 9.2e-15 54.7 0.4 0.00029 20.4 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ44715.1 - 1e-07 31.6 0.1 0.01 15.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ44715.1 - 2.3e-06 27.6 0.0 0.084 12.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KEZ44715.1 - 2.8e-06 27.6 1.2 0.32 11.3 0.0 4.0 2 2 1 3 3 3 2 AAA domain AAA_21 PF13304.6 KEZ44715.1 - 8.8e-06 25.7 1.6 0.055 13.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ44715.1 - 4.5e-05 23.9 4.0 0.029 14.8 0.4 3.5 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KEZ44715.1 - 4.7e-05 22.4 0.3 0.0027 16.6 0.0 3.1 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KEZ44715.1 - 0.00022 20.8 0.1 0.39 10.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 KEZ44715.1 - 0.00029 21.4 0.1 0.38 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KEZ44715.1 - 0.00054 20.1 0.8 0.025 14.7 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KEZ44715.1 - 0.0012 18.6 4.0 0.25 11.0 0.3 3.6 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 KEZ44715.1 - 0.0023 18.1 3.4 2.8 8.2 0.1 4.3 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KEZ44715.1 - 0.0023 18.3 0.8 5.5 7.4 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 KEZ44715.1 - 0.0033 16.5 0.0 0.21 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_5 PF07728.14 KEZ44715.1 - 0.0068 16.4 0.4 6 6.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KEZ44715.1 - 0.01 16.3 0.0 5.5 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ44715.1 - 0.024 14.2 0.5 2 7.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3671 PF12420.8 KEZ44715.1 - 0.03 14.4 4.7 20 5.3 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function AAA_33 PF13671.6 KEZ44715.1 - 0.046 13.9 0.3 20 5.3 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KEZ44715.1 - 0.086 12.5 0.0 8.8 5.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 KEZ44715.1 - 0.12 12.2 0.6 8.4 6.1 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KEZ44715.1 - 0.13 12.0 0.1 13 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ44715.1 - 0.16 12.4 0.1 31 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 KEZ44715.1 - 0.21 11.5 0.0 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Rhomboid PF01694.22 KEZ44715.1 - 0.5 10.4 10.4 0.026 14.5 3.2 2.7 2 0 0 2 2 1 0 Rhomboid family Pyr_redox_2 PF07992.14 KEZ44716.1 - 3.6e-25 88.8 0.0 1.2e-24 87.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ44716.1 - 1.7e-15 57.3 0.9 1.9e-12 47.6 1.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ44716.1 - 0.00021 20.4 0.0 0.00039 19.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.6 KEZ44716.1 - 0.00078 18.7 0.1 0.0016 17.7 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ44716.1 - 0.00081 18.7 0.1 0.059 12.6 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ44716.1 - 0.012 15.0 2.1 1.3 8.3 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ44716.1 - 0.012 14.8 0.6 0.049 12.9 0.1 2.0 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KEZ44716.1 - 0.017 14.7 0.1 0.16 11.5 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ44716.1 - 0.028 13.1 1.9 0.12 11.0 0.2 2.6 2 1 1 3 3 3 0 HI0933-like protein GIDA PF01134.22 KEZ44716.1 - 0.087 11.9 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KEZ44716.1 - 0.13 12.5 0.7 0.94 9.8 0.0 2.4 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEZ44716.1 - 0.22 10.3 0.1 1 8.1 0.2 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 KEZ44716.1 - 0.59 10.6 3.3 1 9.8 0.7 2.5 3 1 0 3 3 3 0 Putative NAD(P)-binding AMP-binding PF00501.28 KEZ44717.1 - 6.4e-99 331.4 0.0 7.3e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ44717.1 - 3.1e-11 44.1 0.0 6.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CsgE PF10627.9 KEZ44718.1 - 0.42 10.9 1.3 1.2 9.3 1.3 1.7 1 0 0 1 1 1 0 Curli assembly protein CsgE OCC1 PF15506.6 KEZ44718.1 - 0.45 10.7 4.5 0.21 11.7 0.5 2.6 2 0 0 2 2 2 0 OCC1 family PAPA-1 PF04795.12 KEZ44719.1 - 4.1e-30 104.4 3.4 4.1e-30 104.4 3.4 3.4 3 0 0 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.13 KEZ44720.1 - 3e-27 96.2 0.8 3e-27 96.2 0.8 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5333 PF17267.2 KEZ44720.1 - 0.054 13.7 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5333) AIP3 PF03915.13 KEZ44720.1 - 0.079 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Ribosomal_60s PF00428.19 KEZ44720.1 - 0.19 12.3 0.1 0.19 12.3 0.1 2.6 3 1 0 3 3 3 0 60s Acidic ribosomal protein CitF PF04223.12 KEZ44720.1 - 0.21 10.5 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) HBM PF16591.5 KEZ44720.1 - 0.61 9.5 2.8 16 4.8 0.4 2.1 2 0 0 2 2 2 0 Helical bimodular sensor domain Chromo PF00385.24 KEZ44721.1 - 5.3e-08 32.6 0.1 1.1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.22 KEZ44722.1 - 8.4e-62 207.5 0.0 1e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ44722.1 - 2.8e-34 117.9 0.0 3.8e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ44722.1 - 9.6e-12 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KEZ44722.1 - 3.9e-07 30.1 0.1 6.2e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ44722.1 - 0.001 19.0 0.5 0.027 14.4 0.1 2.1 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KEZ44722.1 - 0.0023 18.4 0.0 0.0034 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KEZ44722.1 - 0.0027 17.3 0.1 0.0089 15.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KEZ44722.1 - 0.0045 17.3 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 KEZ44722.1 - 0.0061 15.9 0.0 0.0088 15.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 KEZ44722.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 KEZ44722.1 - 0.047 13.1 0.0 0.083 12.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 KEZ44722.1 - 0.06 13.4 0.1 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KEZ44722.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KEZ44722.1 - 0.1 13.1 0.1 0.15 12.6 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KEZ44722.1 - 0.16 11.7 0.7 0.24 11.2 0.6 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Brix PF04427.18 KEZ44723.1 - 4.7e-35 121.5 0.0 6e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain F-box PF00646.33 KEZ44724.1 - 7.8e-07 28.8 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KEZ44724.1 - 2.5e-05 24.1 2.1 0.00021 21.1 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KEZ44724.1 - 0.007 16.2 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 F-box Multi_ubiq PF14452.6 KEZ44724.1 - 0.076 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Multiubiquitin PRANC PF09372.10 KEZ44724.1 - 0.16 12.3 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 PRANC domain RNase_H2-Ydr279 PF09468.10 KEZ44724.1 - 0.2 11.9 0.4 4.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Arb2 PF09757.9 KEZ44725.1 - 9.9e-92 306.7 0.0 1.3e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KEZ44725.1 - 1.7e-82 277.3 0.0 2.5e-82 276.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-HC5HC2H PF13771.6 KEZ44727.1 - 5.7e-06 26.5 2.6 1.5e-05 25.2 2.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain VEFS-Box PF09733.9 KEZ44727.1 - 8.8e-06 25.6 0.1 1.7e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein zf-HC5HC2H_2 PF13832.6 KEZ44727.1 - 9.3e-05 22.6 2.8 0.00022 21.4 2.8 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 KEZ44727.1 - 0.0015 18.4 8.3 0.0038 17.1 8.3 1.8 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 KEZ44727.1 - 0.036 14.2 7.9 0.023 14.9 5.1 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain zf_C2H2_ZHX PF18387.1 KEZ44727.1 - 0.061 13.0 0.4 0.19 11.4 0.4 1.8 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-rbx1 PF12678.7 KEZ44727.1 - 0.94 9.8 5.8 0.6 10.4 3.2 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEZ44727.1 - 2.7 8.4 12.0 1.5 9.2 9.0 2.2 2 0 0 2 2 2 0 Ring finger domain zf-met PF12874.7 KEZ44727.1 - 4.8 7.7 5.1 1.1 9.8 0.3 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type TPT PF03151.16 KEZ44728.1 - 1.4e-56 192.0 8.1 1.7e-56 191.7 8.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KEZ44728.1 - 2e-09 37.7 25.5 6e-06 26.5 10.3 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KEZ44728.1 - 1.4e-06 27.7 13.5 1.6e-05 24.3 13.5 2.1 1 1 0 1 1 1 1 UAA transporter family ORC5_C PF14630.6 KEZ44729.1 - 3.4e-80 269.6 0.0 4.3e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 KEZ44729.1 - 4.8e-16 59.6 0.0 1e-15 58.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ44729.1 - 0.0042 17.4 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KEZ44729.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 KEZ44729.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KEZ44729.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 KEZ44729.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Esterase_phd PF10503.9 KEZ44730.1 - 1.4e-20 73.8 1.4 1.4e-20 73.7 0.1 1.5 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ44730.1 - 3.8e-05 23.3 0.2 6.1e-05 22.6 0.2 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 KEZ44730.1 - 0.00028 19.7 0.2 0.14 10.8 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KEZ44730.1 - 0.0056 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KEZ44730.1 - 0.0057 16.3 0.2 0.0082 15.8 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KEZ44730.1 - 0.0069 16.1 1.1 0.022 14.4 1.1 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KEZ44730.1 - 0.014 15.3 0.5 0.025 14.4 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S51 PF03575.17 KEZ44730.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 ATP-synt_ab PF00006.25 KEZ44731.1 - 4.3e-62 209.5 0.0 7.1e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KEZ44731.1 - 1.9e-22 79.5 0.3 1.3e-21 76.9 0.2 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 KEZ44731.1 - 0.012 15.5 0.3 0.027 14.4 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase T3SS_ATPase_C PF18269.1 KEZ44731.1 - 0.017 15.0 0.9 0.087 12.7 0.9 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 KEZ44731.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KEZ44731.1 - 0.02 14.1 0.5 0.081 12.1 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 KEZ44731.1 - 0.025 15.0 0.1 0.76 10.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEZ44731.1 - 0.033 14.5 0.6 0.48 10.8 0.2 2.4 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 KEZ44731.1 - 0.04 13.3 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 KEZ44731.1 - 0.049 13.6 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KEZ44731.1 - 0.074 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KEZ44731.1 - 0.15 12.4 0.1 0.51 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Alpha-amylase_C PF02806.18 KEZ44732.1 - 1.1e-27 96.4 0.1 3.7e-27 94.6 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KEZ44732.1 - 1.5e-19 70.1 0.0 5.9e-19 68.2 0.0 2.1 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KEZ44732.1 - 1.2e-15 57.9 0.1 9.7e-12 45.1 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 KEZ44732.1 - 0.045 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase AAA_2 PF07724.14 KEZ44733.1 - 4.4e-33 114.8 0.0 1.7e-32 112.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KEZ44733.1 - 4.3e-12 46.6 0.0 8.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KEZ44733.1 - 5.1e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KEZ44733.1 - 1.3e-07 31.7 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KEZ44733.1 - 2.1e-05 23.8 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 KEZ44733.1 - 0.0014 18.9 1.5 0.025 14.8 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEZ44733.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KEZ44733.1 - 0.0087 16.5 0.0 0.038 14.4 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KEZ44733.1 - 0.0095 15.7 0.0 0.059 13.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 KEZ44733.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 KEZ44733.1 - 0.016 15.2 0.6 0.031 14.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEZ44733.1 - 0.017 15.7 0.0 0.045 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEZ44733.1 - 0.033 13.9 0.1 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 KEZ44733.1 - 0.043 13.2 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 KEZ44733.1 - 0.052 12.9 2.2 0.46 9.9 0.0 2.5 2 1 1 3 3 3 0 Bacterial TniB protein Rad17 PF03215.15 KEZ44733.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Torsin PF06309.11 KEZ44733.1 - 0.088 12.9 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_15 PF13175.6 KEZ44733.1 - 0.096 12.4 0.3 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF1296 PF06972.11 KEZ44733.1 - 0.1 12.7 0.1 5.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) AAA_19 PF13245.6 KEZ44733.1 - 0.22 11.8 0.9 0.69 10.2 0.0 2.1 2 1 0 3 3 2 0 AAA domain COX4 PF02936.14 KEZ44734.1 - 2.7e-44 150.5 0.1 3.2e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Toprim_Crpt PF13342.6 KEZ44734.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Aldedh PF00171.22 KEZ44734.1 - 0.16 10.5 1.1 0.2 10.1 1.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Mus7 PF09462.10 KEZ44735.1 - 3.3e-117 392.9 0.0 3.3e-117 392.9 0.0 1.4 2 0 0 2 2 2 1 Mus7/MMS22 family NAD_binding_4 PF07993.12 KEZ44735.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein PH_TFIIH PF08567.11 KEZ44736.1 - 1.8e-23 82.7 0.0 5e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 KEZ44736.1 - 2.6e-20 72.1 1.1 1.4e-12 47.5 0.1 3.2 3 0 0 3 3 3 2 BSD domain DUF3144 PF11342.8 KEZ44736.1 - 0.55 10.6 3.1 2.3 8.6 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) Transket_pyr PF02779.24 KEZ44738.1 - 6.9e-61 205.0 0.0 1.1e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KEZ44738.1 - 7.5e-58 195.8 0.0 1.1e-57 195.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KEZ44738.1 - 7.8e-57 191.2 0.0 1.3e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KEZ44738.1 - 1.1e-19 69.7 1.9 2.8e-19 68.4 1.9 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Glyco_hydro_15 PF00723.21 KEZ44739.1 - 4.4e-78 263.1 0.0 3.6e-39 134.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KEZ44739.1 - 2.1e-25 88.5 0.1 3.7e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.13 KEZ44740.1 - 6.5e-181 603.1 63.3 7.5e-181 602.9 63.3 1.0 1 0 0 1 1 1 1 SART-1 family DUF3712 PF12505.8 KEZ44742.1 - 5.4e-08 33.2 1.0 6.1e-07 29.7 0.3 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KEZ44742.1 - 7.1e-07 29.7 0.4 0.1 13.2 0.0 4.2 4 1 0 4 4 4 2 Late embryogenesis abundant protein KH_1 PF00013.29 KEZ44743.1 - 1.9e-09 37.2 0.1 2.2e-07 30.6 0.1 2.5 2 0 0 2 2 2 2 KH domain ATLF PF07737.11 KEZ44743.1 - 0.12 11.7 0.2 0.6 9.4 0.0 1.9 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain ACT PF01842.25 KEZ44744.1 - 9.5e-15 54.1 0.2 1.7e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 KEZ44744.1 - 1.1e-14 54.4 0.0 1.9e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 KEZ44744.1 - 7.1e-09 35.4 0.1 1.6e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 KEZ44744.1 - 0.057 13.4 0.0 23 5.1 0.0 2.8 2 0 0 2 2 2 0 ACT domain Myc-LZ PF02344.15 KEZ44744.1 - 0.54 10.4 2.8 0.59 10.3 0.4 2.3 2 0 0 2 2 2 0 Myc leucine zipper domain DUF974 PF06159.13 KEZ44745.1 - 2.4e-78 263.4 0.0 2.9e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) IMS PF00817.20 KEZ44746.1 - 3.4e-36 124.5 0.0 5.5e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KEZ44746.1 - 2.8e-13 50.6 0.2 7e-13 49.3 0.1 1.6 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Ribosomal_L26 PF16906.5 KEZ44747.1 - 9e-38 128.6 1.6 1.1e-37 128.3 1.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KEZ44747.1 - 1.2e-07 31.4 4.0 1.3e-07 31.3 2.4 1.9 2 0 0 2 2 2 1 KOW motif CtaG_Cox11 PF04442.14 KEZ44748.1 - 2.1e-60 203.2 0.1 3.9e-60 202.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Amino_oxidase PF01593.24 KEZ44749.1 - 1.9e-16 60.4 0.0 3.2e-15 56.4 0.0 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ44749.1 - 1.4e-11 44.5 0.3 4.3e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ44749.1 - 0.00015 21.5 0.2 0.0048 16.5 0.2 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ44749.1 - 0.0011 18.3 0.0 0.0048 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ44749.1 - 0.0029 16.4 0.1 0.044 12.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KEZ44749.1 - 0.004 16.3 0.1 0.0069 15.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KEZ44749.1 - 0.0058 16.6 0.0 4.7 7.2 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEZ44749.1 - 0.023 13.9 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ44749.1 - 0.029 14.9 0.0 0.75 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ44749.1 - 0.043 12.9 0.1 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ44749.1 - 0.05 12.9 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEZ44749.1 - 0.065 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain OTCace_N PF02729.21 KEZ44750.1 - 3.6e-42 143.9 0.4 5.1e-42 143.4 0.4 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KEZ44750.1 - 5e-42 143.6 0.0 7.6e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain V-SNARE PF05008.15 KEZ44751.1 - 1.4e-20 73.4 2.7 1.4e-20 73.4 2.7 2.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KEZ44751.1 - 8.4e-17 61.2 1.6 8.4e-17 61.2 1.6 2.5 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KEZ44751.1 - 0.0099 15.8 1.0 0.02 14.8 0.3 1.9 2 0 0 2 2 2 1 Sec20 Phycobilisome PF00502.19 KEZ44751.1 - 0.016 15.1 0.7 0.041 13.8 0.7 1.6 1 0 0 1 1 1 0 Phycobilisome protein Fusion_gly PF00523.18 KEZ44751.1 - 0.073 11.3 1.1 0.21 9.8 0.2 1.9 2 0 0 2 2 2 0 Fusion glycoprotein F0 CDC14 PF08045.11 KEZ44751.1 - 0.14 11.3 2.8 0.081 12.0 0.5 1.7 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Synaptobrevin PF00957.21 KEZ44751.1 - 0.18 11.6 2.1 0.31 10.8 0.5 2.0 1 1 0 2 2 2 0 Synaptobrevin FAM76 PF16046.5 KEZ44751.1 - 0.22 10.8 2.5 0.1 11.9 0.5 1.4 2 0 0 2 2 2 0 FAM76 protein Use1 PF09753.9 KEZ44751.1 - 0.39 10.4 8.3 12 5.5 8.3 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 YqjK PF13997.6 KEZ44751.1 - 4.9 7.5 8.2 7.8 6.8 0.1 3.2 3 1 1 4 4 4 0 YqjK-like protein DarA_C PF18789.1 KEZ44752.1 - 0.061 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Defence against restriction A C-terminal SET PF00856.28 KEZ44753.1 - 0.034 14.5 0.5 0.29 11.5 0.0 2.2 2 1 0 2 2 2 0 SET domain DUF1631 PF07793.11 KEZ44753.1 - 0.25 9.7 2.9 0.32 9.4 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Ala_racemase_N PF01168.20 KEZ44754.1 - 1.2e-22 80.7 0.0 1.5e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Thioredoxin_8 PF13905.6 KEZ44754.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Adaptin_N PF01602.20 KEZ44755.1 - 3.5e-119 398.7 5.1 4.2e-119 398.5 5.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KEZ44755.1 - 8.9e-46 154.7 0.0 2.2e-45 153.5 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KEZ44755.1 - 1.6e-13 51.0 0.0 2.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KEZ44755.1 - 0.034 14.3 0.1 0.13 12.4 0.1 2.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Methyltransf_23 PF13489.6 KEZ44756.1 - 3e-10 40.2 0.0 4.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44756.1 - 1.7e-09 38.2 0.0 4.2e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44756.1 - 2e-07 31.6 0.0 9.2e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44756.1 - 4.4e-07 30.5 0.0 7.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44756.1 - 0.00024 20.9 0.0 0.00053 19.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44756.1 - 0.0024 17.2 0.0 0.0052 16.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 KEZ44757.1 - 5.7e-34 117.7 0.0 7.6e-28 97.9 0.0 2.1 1 1 1 2 2 2 2 ARP2/3 complex 16 kDa subunit (p16-Arc) RunxI PF08504.11 KEZ44757.1 - 0.086 13.5 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Runx inhibition domain CN_hydrolase PF00795.22 KEZ44758.1 - 1.5e-48 165.4 0.0 2.2e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.14 KEZ44758.1 - 2.5e-19 70.1 12.1 2.8e-17 63.4 10.8 3.0 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family PCP_red PF08369.10 KEZ44758.1 - 0.053 13.7 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit CPSF73-100_C PF11718.8 KEZ44759.1 - 1.4e-81 273.1 0.0 2.1e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KEZ44759.1 - 4.6e-31 107.4 0.0 9.2e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KEZ44759.1 - 4.6e-19 69.2 0.3 9.3e-19 68.2 0.3 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KEZ44759.1 - 6.8e-16 58.3 0.1 1.4e-15 57.2 0.0 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KEZ44759.1 - 1.1e-14 54.1 0.1 2.3e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KEZ44759.1 - 5e-07 29.4 0.5 1.3e-06 28.1 0.5 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KEZ44759.1 - 1.3e-05 25.2 0.0 3.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain V_ATPase_I PF01496.19 KEZ44760.1 - 0 1026.2 0.0 0 1026.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LRR_6 PF13516.6 KEZ44760.1 - 0.00091 19.1 2.7 0.81 9.9 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich repeat DUF1465 PF07323.12 KEZ44760.1 - 0.049 13.5 0.1 0.43 10.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) LRR_4 PF12799.7 KEZ44760.1 - 0.084 13.3 0.3 17 6.0 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) CheZ PF04344.13 KEZ44760.1 - 0.28 11.1 2.9 0.38 10.7 0.2 2.1 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ CENP-Q PF13094.6 KEZ44760.1 - 0.29 11.3 1.2 0.76 10.0 1.1 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.6 KEZ44760.1 - 2 8.1 4.1 17 5.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) ING PF12998.7 KEZ44761.1 - 2.6e-11 44.0 0.0 3.7e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KEZ44761.1 - 3.2e-06 26.9 8.2 5.8e-06 26.1 8.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KEZ44761.1 - 0.13 12.5 4.3 0.36 11.1 4.2 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Prenyltransf PF01255.19 KEZ44762.1 - 5.9e-82 274.5 0.0 1.5e-81 273.2 0.0 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rhomboid PF01694.22 KEZ44763.1 - 5.7e-06 26.4 0.9 1.3e-05 25.3 0.9 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KEZ44763.1 - 5e-05 23.8 1.4 8.3e-05 23.1 0.8 1.7 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.15 KEZ44763.1 - 0.0056 16.6 2.5 0.0091 15.9 2.5 1.3 1 0 0 1 1 1 1 Der1-like family TFIID-18kDa PF02269.16 KEZ44764.1 - 6.8e-18 64.5 0.0 1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 KEZ44764.1 - 0.00036 20.9 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 KEZ44764.1 - 0.00049 20.5 0.3 0.0013 19.1 0.0 1.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KEZ44764.1 - 0.00052 20.2 0.8 0.0056 16.9 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KEZ44764.1 - 0.00053 20.1 0.0 0.00079 19.5 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KEZ44764.1 - 0.0044 17.0 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated DLP_helical PF18709.1 KEZ44764.1 - 0.015 14.5 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain TFIID_20kDa PF03847.13 KEZ44764.1 - 0.053 14.0 0.1 0.14 12.7 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Uds1 PF15456.6 KEZ44765.1 - 2.8e-42 144.0 1.8 2.8e-42 144.0 1.8 8.3 4 2 4 8 8 8 1 Up-regulated During Septation HR1 PF02185.16 KEZ44765.1 - 2.6e-06 27.4 0.1 2.6e-06 27.4 0.1 10.3 10 2 0 10 10 10 1 Hr1 repeat Img2 PF05046.14 KEZ44765.1 - 0.0017 18.6 1.3 0.13 12.6 0.1 3.1 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) HalX PF08663.10 KEZ44765.1 - 0.0029 17.9 1.5 0.0029 17.9 1.5 11.1 10 4 2 12 12 11 1 HalX domain BST2 PF16716.5 KEZ44765.1 - 0.0064 17.1 5.4 0.0064 17.1 5.4 10.9 8 3 3 11 11 11 1 Bone marrow stromal antigen 2 ZapB PF06005.12 KEZ44765.1 - 0.019 15.4 3.8 0.019 15.4 3.8 10.4 8 3 1 9 9 7 0 Cell division protein ZapB DUF3606 PF12244.8 KEZ44765.1 - 0.06 13.3 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) MtrG PF04210.13 KEZ44765.1 - 0.68 9.8 3.5 4.3 7.3 0.1 3.7 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Shugoshin_N PF07558.11 KEZ44765.1 - 1.1 9.2 8.1 6.1 6.8 0.1 4.5 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 KEZ44765.1 - 1.8 7.4 91.3 0.039 12.8 16.1 6.5 5 1 2 7 7 7 0 Spc7 kinetochore protein PAP_central PF04928.17 KEZ44765.1 - 3.6 6.5 7.2 0.26 10.2 1.6 2.0 2 0 0 2 2 2 0 Poly(A) polymerase central domain TLE_N PF03920.15 KEZ44765.1 - 7.6 6.6 13.0 0.37 10.9 0.3 4.3 4 1 0 4 4 4 0 Groucho/TLE N-terminal Q-rich domain Ric8 PF10165.9 KEZ44766.1 - 1.4e-76 258.4 0.0 1.8e-76 258.0 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn TIP49 PF06068.13 KEZ44767.1 - 5.7e-168 558.6 0.0 8.9e-168 557.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KEZ44767.1 - 4e-23 81.3 0.0 1.2e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KEZ44767.1 - 7.2e-11 42.6 0.4 6.5e-07 29.8 0.1 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KEZ44767.1 - 1.6e-09 37.7 0.1 1.1e-06 28.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KEZ44767.1 - 4.4e-05 23.8 0.3 0.074 13.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KEZ44767.1 - 0.00036 20.8 0.2 0.0037 17.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ44767.1 - 0.00053 20.4 0.1 0.0058 17.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KEZ44767.1 - 0.0031 17.9 3.3 0.18 12.1 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEZ44767.1 - 0.0032 17.4 0.2 0.21 11.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KEZ44767.1 - 0.011 15.3 0.1 0.068 12.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KEZ44767.1 - 0.017 14.5 0.1 0.64 9.4 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KEZ44767.1 - 0.018 15.6 0.0 0.045 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ44767.1 - 0.024 13.9 0.2 0.067 12.5 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KEZ44767.1 - 0.031 14.0 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 KEZ44767.1 - 0.053 13.2 0.2 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KEZ44767.1 - 0.065 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 KEZ44767.1 - 0.066 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KEZ44767.1 - 0.096 11.9 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KEZ44767.1 - 0.17 11.4 0.1 0.4 10.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region HMG_box PF00505.19 KEZ44768.1 - 6.5e-22 77.7 1.0 1.4e-21 76.7 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KEZ44768.1 - 8.7e-07 29.4 0.7 1.8e-06 28.4 0.7 1.6 1 0 0 1 1 1 1 HMG-box domain Dynactin PF12455.8 KEZ44769.1 - 1.1e-104 349.7 9.2 1.1e-104 349.7 9.2 3.8 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KEZ44769.1 - 6.2e-22 77.4 0.4 1.2e-21 76.5 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain GST_C_3 PF14497.6 KEZ44769.1 - 0.1 12.8 0.0 0.47 10.7 0.0 2.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 KEZ44770.1 - 9.1e-07 28.9 11.1 1.9e-06 27.9 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CC PF04942.14 KEZ44770.1 - 0.0081 16.3 1.8 0.022 14.9 1.8 1.7 1 0 0 1 1 1 1 CC domain DUF3716 PF12511.8 KEZ44770.1 - 0.5 10.4 6.2 1.4 9.1 6.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) CDP-OH_P_transf PF01066.21 KEZ44771.1 - 1.6e-13 51.2 0.2 1.6e-13 51.2 0.2 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 KEZ44771.1 - 0.067 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Thermopsin Het-C PF07217.11 KEZ44773.1 - 1.7e-272 905.0 0.0 2e-272 904.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cyt-b5 PF00173.28 KEZ44774.1 - 2e-16 59.9 1.4 4.1e-16 58.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KEZ44774.1 - 2.6e-12 47.3 20.8 2.6e-12 47.3 20.8 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1453 PF07301.11 KEZ44774.1 - 0.017 15.1 0.3 0.029 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Anth_synt_I_N PF04715.13 KEZ44774.1 - 0.067 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 KEZ44774.1 - 0.12 12.3 0.3 0.32 10.9 0.3 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RRM_1 PF00076.22 KEZ44775.1 - 7e-44 147.5 1.7 8.6e-21 73.5 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KEZ44775.1 - 2.4e-23 83.0 0.1 7.8e-23 81.4 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KEZ44775.1 - 1.2e-05 25.1 0.0 0.018 14.9 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KEZ44775.1 - 0.0051 16.8 0.0 1.2 9.2 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KEZ44775.1 - 0.0065 16.6 0.1 0.88 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif PHM7_cyt PF14703.6 KEZ44775.1 - 0.0073 16.6 0.3 0.37 11.0 0.3 3.3 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KEZ44775.1 - 0.013 15.5 1.2 0.21 11.7 0.0 3.0 3 1 0 3 3 3 0 RNA binding motif RRM_5 PF13893.6 KEZ44775.1 - 0.016 14.8 0.0 0.14 11.8 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 KEZ44775.1 - 0.026 14.4 0.0 1.8 8.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1866) Aminotran_1_2 PF00155.21 KEZ44777.1 - 1.5e-33 116.5 0.0 4.4e-33 114.9 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class I and II VWA PF00092.28 KEZ44778.1 - 9.2e-08 32.5 0.0 2.6e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KEZ44778.1 - 1.8e-06 28.5 0.0 4.5e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KEZ44778.1 - 0.0015 18.7 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus EP400_N PF15790.5 KEZ44778.1 - 0.16 10.8 4.4 0.25 10.1 4.4 1.2 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal GEN1_C PF18380.1 KEZ44779.1 - 3.5e-27 95.4 0.0 3.5e-27 95.4 0.0 3.6 4 0 0 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KEZ44779.1 - 3.2e-25 88.3 0.0 6.5e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KEZ44779.1 - 9e-08 32.5 0.0 1.9e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain TFIIA PF03153.13 KEZ44779.1 - 6.6 6.6 8.4 11 5.9 8.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C12 PF01088.21 KEZ44781.1 - 1.1e-47 162.6 0.0 8.3e-47 159.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Actin PF00022.19 KEZ44782.1 - 4.6e-19 68.3 0.0 3.3e-17 62.2 0.0 3.2 2 1 0 2 2 2 1 Actin WW PF00397.26 KEZ44783.1 - 3.3e-09 36.7 0.1 6.9e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 WW domain Pga1 PF10333.9 KEZ44784.1 - 3.6e-07 30.2 0.1 6e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator WPP PF13943.6 KEZ44784.1 - 0.11 12.9 0.0 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 WPP domain His_biosynth PF00977.21 KEZ44785.1 - 6e-38 130.6 0.0 7.4e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KEZ44785.1 - 0.081 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Tubulin PF00091.25 KEZ44786.1 - 4.8e-66 222.7 0.0 7.1e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KEZ44786.1 - 2.3e-50 170.0 0.1 3.8e-50 169.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KEZ44786.1 - 0.0073 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain EF-hand_4 PF12763.7 KEZ44787.1 - 9.4e-34 115.5 0.0 2.5e-13 49.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KEZ44787.1 - 9.7e-07 29.2 0.0 0.00078 19.9 0.0 3.9 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KEZ44787.1 - 6.1e-05 22.3 0.2 0.69 9.6 0.0 4.6 5 0 0 5 5 4 1 EF hand EF-hand_6 PF13405.6 KEZ44787.1 - 0.0017 18.1 0.6 22 5.3 0.1 4.9 5 0 0 5 5 4 0 EF-hand domain DUF3584 PF12128.8 KEZ44787.1 - 0.0042 14.7 24.4 0.0061 14.2 24.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KEZ44787.1 - 0.013 15.0 20.9 0.025 14.1 20.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 KEZ44787.1 - 0.015 14.7 29.4 0.13 11.6 10.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 KEZ44787.1 - 0.021 14.6 19.7 0.011 15.5 9.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UBA PF00627.31 KEZ44787.1 - 0.044 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain JAKMIP_CC3 PF16034.5 KEZ44787.1 - 0.072 13.0 20.6 0.18 11.7 20.6 1.7 1 0 0 1 1 1 0 JAKMIP CC3 domain EF-hand_8 PF13833.6 KEZ44787.1 - 0.094 12.6 0.0 75 3.3 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair CENP-F_leu_zip PF10473.9 KEZ44787.1 - 0.11 12.5 29.3 0.12 12.4 10.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KEZ44787.1 - 0.13 12.4 24.4 0.44 10.8 4.0 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 KEZ44787.1 - 0.2 10.5 30.0 1.4 7.7 16.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KEZ44787.1 - 0.25 11.9 30.7 2.9 8.4 20.7 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KEZ44787.1 - 0.3 11.3 41.2 0.16 12.2 20.4 3.1 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 KEZ44787.1 - 0.37 10.9 32.8 2.1 8.4 18.5 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 KEZ44787.1 - 0.42 11.0 21.1 0.69 10.3 1.2 4.7 2 1 1 4 4 3 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KEZ44787.1 - 0.53 10.3 15.3 0.11 12.6 7.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FUSC PF04632.12 KEZ44787.1 - 0.57 8.6 9.1 0.93 7.9 9.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 KEZ44787.1 - 0.66 10.1 32.5 0.33 11.0 9.4 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 KEZ44787.1 - 0.85 10.0 18.7 0.18 12.2 2.2 3.6 2 2 1 3 3 3 0 Csm1 N-terminal domain DUF4763 PF15960.5 KEZ44787.1 - 0.98 8.7 21.5 1.1 8.5 10.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4763) MscS_porin PF12795.7 KEZ44787.1 - 0.99 8.9 41.0 1.9 8.0 13.7 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.6 KEZ44787.1 - 1 7.9 20.2 3.8 6.0 5.4 2.2 1 1 1 2 2 2 0 AAA domain DivIC PF04977.15 KEZ44787.1 - 1.4 8.8 26.6 0.3 10.9 7.0 4.1 1 1 3 4 4 4 0 Septum formation initiator HAP1_N PF04849.13 KEZ44787.1 - 1.4 8.1 25.5 0.23 10.6 16.3 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF4201 PF13870.6 KEZ44787.1 - 1.4 8.6 25.7 0.79 9.4 17.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.21 KEZ44787.1 - 1.4 8.4 26.4 0.42 10.1 10.8 2.3 1 1 0 2 2 2 0 Intermediate filament protein PRKG1_interact PF15898.5 KEZ44787.1 - 1.4 9.9 27.0 0.087 13.7 9.3 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain HrpB7 PF09486.10 KEZ44787.1 - 1.9 8.9 16.8 4.4 7.7 16.8 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF812 PF05667.11 KEZ44787.1 - 2 7.2 28.8 0.043 12.7 20.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) kleA_kleC PF17383.2 KEZ44787.1 - 2.1 8.7 6.4 31 5.0 2.0 3.4 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A DUF2730 PF10805.8 KEZ44787.1 - 2.4 8.3 10.6 2.5 8.2 4.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Exonuc_VII_L PF02601.15 KEZ44787.1 - 2.6 7.6 16.2 5.5 6.5 16.2 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit HemX PF04375.14 KEZ44787.1 - 3.7 6.7 32.4 2.6 7.2 11.7 2.3 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase MbeD_MobD PF04899.12 KEZ44787.1 - 3.8 7.7 17.3 8.7 6.5 0.6 3.8 2 1 2 4 4 3 0 MbeD/MobD like Allexi_40kDa PF05549.11 KEZ44787.1 - 3.9 6.9 16.6 7.6 6.0 3.5 2.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein SHE3 PF17078.5 KEZ44787.1 - 4.2 7.0 20.2 17 5.0 20.3 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Fib_alpha PF08702.10 KEZ44787.1 - 4.3 7.5 20.5 0.61 10.3 11.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DegS PF05384.11 KEZ44787.1 - 4.7 6.7 16.5 1.5 8.3 3.6 2.3 1 1 1 2 2 2 0 Sensor protein DegS Occludin_ELL PF07303.13 KEZ44787.1 - 5.1 7.9 13.6 1.1 10.0 4.4 3.2 2 1 1 3 3 3 0 Occludin homology domain DUF3450 PF11932.8 KEZ44787.1 - 5.1 6.3 32.7 0.86 8.9 11.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4200 PF13863.6 KEZ44787.1 - 7.5 7.0 24.4 14 6.1 18.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.6 KEZ44787.1 - 9.2 6.3 37.6 58 3.8 15.4 3.1 1 1 1 2 2 2 0 FlxA-like protein LsmAD PF06741.13 KEZ44788.1 - 8e-28 96.8 2.3 8e-28 96.8 2.3 2.6 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.20 KEZ44789.1 - 2.7e-19 69.6 0.1 5.5e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KEZ44789.1 - 7.2e-12 45.7 0.0 1.6e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain BMC PF00936.19 KEZ44789.1 - 0.043 13.8 2.7 0.06 13.3 0.6 2.3 2 0 0 2 2 2 0 BMC domain LPP20 PF02169.16 KEZ44789.1 - 4 7.8 9.4 8.8 6.8 0.2 2.8 2 1 0 2 2 2 0 LPP20 lipoprotein RNA_pol_Rpc82 PF05645.13 KEZ44790.1 - 5.9e-40 137.6 0.0 1e-36 127.0 0.0 2.7 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KEZ44790.1 - 8.2e-19 67.5 0.0 1.2e-17 63.7 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KEZ44790.1 - 4.9e-07 29.6 0.1 0.0037 17.1 0.0 3.1 2 0 0 2 2 2 2 TFIIE alpha subunit HTH_IclR PF09339.10 KEZ44790.1 - 1.8e-05 24.4 1.1 0.037 13.8 0.0 3.7 3 0 0 3 3 3 2 IclR helix-turn-helix domain MarR_2 PF12802.7 KEZ44790.1 - 0.0046 16.8 0.1 6.3 6.8 0.1 2.9 2 0 0 2 2 2 2 MarR family HTH_5 PF01022.20 KEZ44790.1 - 0.0076 16.1 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 KEZ44790.1 - 0.0098 15.8 0.0 0.16 11.9 0.0 2.8 3 0 0 3 3 3 1 MarR family Mito_carr PF00153.27 KEZ44791.1 - 4e-31 106.8 0.7 3.9e-15 55.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Fe_dep_repress PF01325.19 KEZ44792.1 - 0.02 15.1 5.3 0.13 12.5 0.6 3.7 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain HWE_HK PF07536.14 KEZ44792.1 - 0.74 10.6 5.8 0.61 10.8 0.1 3.9 3 0 0 3 3 3 0 HWE histidine kinase RbsD_FucU PF05025.13 KEZ44792.1 - 1.1 9.7 8.8 1.5 9.2 1.8 4.6 4 0 0 4 4 4 0 RbsD / FucU transport protein family AKNA PF12443.8 KEZ44792.1 - 3.9 8.2 14.5 4.6 8.0 0.1 5.5 5 1 1 6 6 6 0 AT-hook-containing transcription factor Rax2 PF12768.7 KEZ44793.1 - 0.015 14.8 0.0 0.039 13.4 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SKG6 PF08693.10 KEZ44793.1 - 0.026 13.9 0.0 0.026 13.9 0.0 2.0 2 1 0 2 2 1 0 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.11 KEZ44793.1 - 0.029 12.5 3.4 0.035 12.2 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 KEZ44793.1 - 0.031 13.1 1.3 0.033 13.1 1.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 KEZ44793.1 - 0.095 12.3 15.0 0.16 11.6 15.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 KEZ44793.1 - 0.14 10.9 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Presenilin PH_4 PF15404.6 KEZ44793.1 - 0.16 11.8 0.3 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Macoilin PF09726.9 KEZ44793.1 - 0.18 10.4 2.2 0.17 10.4 2.2 1.1 1 0 0 1 1 1 0 Macoilin family EBP50_C PF09007.11 KEZ44793.1 - 0.35 11.9 8.0 0.12 13.4 5.0 1.6 2 0 0 2 2 2 0 EBP50, C-terminal SSP160 PF06933.11 KEZ44793.1 - 0.54 8.4 12.1 0.74 7.9 12.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 KEZ44793.1 - 7.7 4.8 13.3 10 4.4 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mannosyl_trans3 PF11051.8 KEZ44794.1 - 9.5e-42 143.2 0.0 3.1e-41 141.6 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative NADH-G_4Fe-4S_3 PF10588.9 KEZ44794.1 - 1.6e-11 43.5 0.5 3.3e-11 42.5 0.3 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DENN PF02141.21 KEZ44795.1 - 7e-40 137.0 0.1 1.2e-39 136.2 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KEZ44795.1 - 7.1e-07 29.9 0.3 2.7e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 KEZ44795.1 - 0.42 11.2 11.6 0.029 14.9 5.5 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TMF_TATA_bd PF12325.8 KEZ44795.1 - 6.6 7.0 17.3 2.2 8.5 4.8 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1899 PF08953.11 KEZ44796.1 - 1.2e-34 118.0 0.1 2.2e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KEZ44796.1 - 4.1e-19 68.2 0.1 7.5e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KEZ44796.1 - 2.9e-17 62.7 4.6 4.3e-05 24.2 0.3 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ44796.1 - 3.4e-07 30.5 0.2 0.015 15.6 0.1 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KEZ44796.1 - 0.021 13.5 0.3 0.24 10.0 0.3 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ44796.1 - 0.061 12.3 0.0 1 8.2 0.1 2.2 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Syntaxin-6_N PF09177.11 KEZ44797.1 - 0.016 15.8 2.2 0.51 10.9 0.4 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1678 PF07913.11 KEZ44797.1 - 0.04 13.7 0.1 0.096 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) zf-C2H2_3 PF13878.6 KEZ44797.1 - 0.11 12.4 0.1 0.33 10.8 0.1 1.9 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO HypA PF01155.19 KEZ44797.1 - 0.16 12.0 0.5 0.45 10.6 0.1 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CorA PF01544.18 KEZ44797.1 - 0.38 10.0 4.3 0.79 9.0 0.5 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein zf-C4pol PF14260.6 KEZ44797.1 - 8.3 7.0 7.2 13 6.3 1.6 2.9 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Anillin PF08174.11 KEZ44798.1 - 1.4e-10 41.7 0.0 3.9e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KEZ44798.1 - 6.2e-08 33.1 0.0 2e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KEZ44798.1 - 0.14 12.6 0.3 0.74 10.3 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain DEAD PF00270.29 KEZ44799.1 - 1.9e-43 148.2 1.2 3e-43 147.6 1.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ44799.1 - 1.1e-31 109.5 0.2 9.8e-31 106.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ44799.1 - 2.3e-07 31.0 0.0 4.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MARCKS PF02063.17 KEZ44799.1 - 0.0021 18.1 0.7 0.0021 18.1 0.7 1.7 2 0 0 2 2 2 1 MARCKS family CCDC-167 PF15188.6 KEZ44799.1 - 0.15 12.4 2.0 1.6 9.1 2.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Methyltransf_23 PF13489.6 KEZ44800.1 - 8e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44800.1 - 1.1e-13 51.6 0.0 1.3e-12 48.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44800.1 - 1.3e-13 51.4 0.0 5.2e-13 49.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44800.1 - 1.5e-10 41.6 0.0 2.1e-09 38.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44800.1 - 1.3e-09 38.0 0.0 0.00056 19.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44800.1 - 0.00015 21.2 0.0 0.006 15.9 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEZ44800.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KEZ44800.1 - 0.0016 17.9 0.0 0.0061 16.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KEZ44800.1 - 0.0043 16.6 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KEZ44800.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 KEZ44800.1 - 0.0082 15.5 0.0 0.025 13.9 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain PrmA PF06325.13 KEZ44800.1 - 0.048 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KEZ44800.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Catalase PF00199.19 KEZ44801.1 - 6.7e-166 552.1 0.0 8.7e-166 551.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KEZ44801.1 - 4.1e-47 159.6 0.1 6.5e-47 159.0 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KEZ44801.1 - 7.7e-20 70.9 0.0 1.4e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF2624 PF11116.8 KEZ44801.1 - 0.13 13.2 0.3 0.26 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Nucleoside_tran PF01733.18 KEZ44802.1 - 2.9e-34 118.9 15.9 2.9e-34 118.9 15.9 3.2 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 KEZ44802.1 - 2.8e-09 36.4 32.2 0.00087 18.3 8.1 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Scs3p PF10261.9 KEZ44802.1 - 0.0066 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Spo7 PF03907.13 KEZ44802.1 - 4.7 6.6 6.6 5.1 6.5 2.5 2.3 2 0 0 2 2 2 0 Spo7-like protein COX14 PF14880.6 KEZ44802.1 - 9.9 6.1 7.4 1.1 9.2 2.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Ins_P5_2-kin PF06090.12 KEZ44803.1 - 3.1e-35 122.2 0.0 5.2e-34 118.2 0.0 2.2 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase YEATS PF03366.16 KEZ44805.1 - 2.9e-29 100.9 0.4 4.8e-29 100.2 0.4 1.4 1 0 0 1 1 1 1 YEATS family NAD_binding_4 PF07993.12 KEZ44806.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.4 2 0 0 2 2 2 0 Male sterility protein Gln-synt_N_2 PF16952.5 KEZ44806.1 - 0.077 12.8 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain Kelch_5 PF13854.6 KEZ44807.1 - 1.3e-14 53.8 11.2 3.1e-12 46.2 0.3 5.3 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.6 KEZ44807.1 - 4.3e-08 33.2 8.3 0.46 10.8 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 KEZ44807.1 - 1.6e-05 24.8 11.6 0.045 13.8 0.3 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KEZ44807.1 - 0.0024 17.8 1.5 18 5.5 0.0 4.7 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 KEZ44807.1 - 0.006 16.1 4.8 8.4 6.1 0.0 5.4 6 0 0 6 6 6 1 Kelch motif MccV PF17508.2 KEZ44807.1 - 0.072 13.7 1.2 0.17 12.4 1.2 1.6 1 0 0 1 1 1 0 Microcin V bacteriocin DUF4690 PF15756.5 KEZ44807.1 - 0.98 10.1 2.6 1 10.0 0.1 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Ecl1 PF12855.7 KEZ44808.1 - 2.4e-32 113.5 9.2 2.4e-32 113.5 9.2 2.1 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins PhoLip_ATPase_C PF16212.5 KEZ44809.1 - 1e-81 274.4 18.8 1e-81 274.4 18.8 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEZ44809.1 - 1.4e-27 95.2 5.8 3.7e-27 93.8 5.8 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KEZ44809.1 - 8.3e-12 45.8 3.1 3.8e-07 30.6 0.9 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ44809.1 - 5.4e-11 42.4 0.0 2.7e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KEZ44809.1 - 7.2e-08 32.2 0.1 1.7e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEZ44809.1 - 0.0015 18.4 0.3 0.0091 15.8 0.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Delta_lysin PF05372.11 KEZ44809.1 - 0.037 13.3 0.7 0.095 12.0 0.7 1.6 1 0 0 1 1 1 0 Delta lysin family Pinin_SDK_memA PF04696.13 KEZ44811.1 - 8.1e-23 80.9 17.2 8.1e-23 80.9 17.2 2.5 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF5415 PF17436.2 KEZ44811.1 - 0.016 15.3 0.8 0.016 15.3 0.8 3.5 1 1 2 3 3 3 0 Family of unknown function (DUF5415) RGS-like PF09128.11 KEZ44811.1 - 0.016 14.9 4.8 0.037 13.7 0.1 2.3 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain PHF5 PF03660.14 KEZ44812.1 - 1.1e-52 176.5 10.2 1.3e-52 176.4 10.2 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KEZ44812.1 - 0.25 9.2 6.4 0.26 9.1 6.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KEZ44812.1 - 2 8.5 15.7 6 7.0 2.0 3.1 1 1 1 2 2 2 0 Double zinc ribbon Pex26 PF07163.12 KEZ44813.1 - 0.00032 20.1 5.6 0.00067 19.1 5.1 1.7 2 0 0 2 2 2 1 Pex26 protein TPH PF13868.6 KEZ44813.1 - 0.0083 14.7 35.5 0.012 14.1 35.5 1.1 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain DUF1451 PF07295.11 KEZ44813.1 - 2.7 8.0 10.3 4.7 7.2 10.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain OmpH PF03938.14 KEZ44813.1 - 7.4 6.9 13.7 14 6.0 13.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Haspin_kinase PF12330.8 KEZ44814.1 - 1.9e-32 112.6 0.0 2.6e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain ABC1 PF03109.16 KEZ44814.1 - 0.6 10.3 1.8 8.2 6.6 0.6 2.3 2 0 0 2 2 2 0 ABC1 family DUF1764 PF08576.10 KEZ44814.1 - 0.88 10.5 4.7 1.5 9.8 4.1 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF1682 PF07946.14 KEZ44815.1 - 1.2e-111 373.1 0.8 1.4e-111 372.8 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) LUC7 PF03194.15 KEZ44815.1 - 0.49 10.0 9.1 0.85 9.2 9.1 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Thiamine_BP PF01910.17 KEZ44816.1 - 4.3e-32 109.9 0.0 5.2e-32 109.6 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein PI-PLC-X PF00388.19 KEZ44817.1 - 3.7e-64 214.7 0.0 5.6e-64 214.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KEZ44817.1 - 2.2e-42 144.0 0.0 4e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain SspP PF08179.12 KEZ44817.1 - 0.58 10.6 2.6 1.2 9.7 0.7 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein P family Voltage_CLC PF00654.20 KEZ44818.1 - 1.1e-89 301.2 21.1 1.1e-89 301.2 21.1 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel Mso1_C PF14477.6 KEZ44818.1 - 0.068 13.6 2.3 0.15 12.5 2.3 1.5 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 NRDE-2 PF08424.10 KEZ44819.1 - 6.9e-88 294.9 0.0 3.3e-87 292.6 0.0 2.0 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KEZ44819.1 - 0.00061 20.4 2.2 4.8 8.3 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat SelP_N PF04592.14 KEZ44819.1 - 9.3 5.6 9.6 18 4.6 9.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Aminotran_3 PF00202.21 KEZ44820.1 - 1.2e-118 396.3 0.0 1.5e-118 396.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEZ44820.1 - 0.0043 16.3 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SRI PF08236.11 KEZ44822.1 - 1.9e-23 82.5 7.9 4.1e-23 81.3 7.9 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KEZ44822.1 - 3.1e-18 66.8 0.1 3.1e-18 66.8 0.1 3.6 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KEZ44822.1 - 3.8e-14 52.4 4.4 3.8e-14 52.4 4.4 2.1 2 0 0 2 2 2 1 AWS domain WW PF00397.26 KEZ44822.1 - 7.6e-06 25.9 1.7 1.7e-05 24.8 1.7 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 KEZ44822.1 - 0.00059 19.8 0.1 0.0035 17.3 0.1 2.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Arm_3 PF16186.5 KEZ44822.1 - 0.035 13.7 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Atypical Arm repeat ThiF PF00899.21 KEZ44824.1 - 2.4e-29 102.4 0.0 4.1e-29 101.7 0.0 1.3 1 1 0 1 1 1 1 ThiF family SDA1 PF05285.12 KEZ44825.1 - 0.00021 20.8 12.0 0.00033 20.2 12.0 1.4 1 0 0 1 1 1 1 SDA1 Paf1 PF03985.13 KEZ44825.1 - 0.0034 16.5 13.4 0.0046 16.0 12.0 1.8 2 0 0 2 2 2 1 Paf1 Nop14 PF04147.12 KEZ44825.1 - 0.0037 15.6 20.2 0.0052 15.1 20.2 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 KEZ44825.1 - 0.0044 16.4 14.1 0.0044 16.4 14.1 1.7 2 0 0 2 2 2 1 BUD22 Mpp10 PF04006.12 KEZ44825.1 - 0.012 14.1 15.7 0.02 13.4 15.7 1.3 1 0 0 1 1 1 0 Mpp10 protein Tim54 PF11711.8 KEZ44825.1 - 0.072 11.9 2.2 0.13 11.0 2.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_3_Rpc31 PF11705.8 KEZ44825.1 - 0.17 12.1 28.7 0.025 14.9 23.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CAF1A PF12253.8 KEZ44825.1 - 0.29 11.4 24.9 1.1 9.5 24.9 2.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A DNA_pol_phi PF04931.13 KEZ44825.1 - 0.31 9.1 34.3 0.43 8.6 34.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 KEZ44825.1 - 0.34 10.6 27.7 0.085 12.6 21.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 KEZ44825.1 - 0.45 9.2 3.3 0.7 8.6 3.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5523 PF17661.1 KEZ44825.1 - 0.57 9.8 12.5 1.3 8.7 12.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RPN2_C PF18004.1 KEZ44825.1 - 0.6 10.0 6.8 1.2 9.0 6.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sigma70_ner PF04546.13 KEZ44825.1 - 0.68 9.8 16.8 1.1 9.0 16.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TFB6 PF17110.5 KEZ44825.1 - 1.3 8.7 10.4 2.8 7.6 10.4 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 KEZ44825.1 - 1.9 6.7 21.4 0.16 10.2 16.3 1.7 2 0 0 2 2 2 0 CDC45-like protein Pox_Ag35 PF03286.14 KEZ44825.1 - 4.5 7.0 14.4 0.62 9.8 9.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein XAP5 PF04921.14 KEZ44825.1 - 5.8 6.7 10.8 13 5.5 10.8 1.6 1 0 0 1 1 1 0 XAP5, circadian clock regulator CPSF100_C PF13299.6 KEZ44825.1 - 6.1 7.0 8.0 1.4 9.1 4.1 1.8 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Astro_capsid_p PF12226.8 KEZ44825.1 - 6.8 5.7 20.1 11 5.0 20.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RR_TM4-6 PF06459.12 KEZ44825.1 - 7.1 6.4 9.4 2.8 7.7 6.2 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 KEZ44825.1 - 8.9 5.8 23.3 0.19 11.3 15.6 2.0 2 0 0 2 2 2 0 PPP4R2 eIF-6 PF01912.18 KEZ44826.1 - 1.1e-64 217.4 0.9 1.5e-57 194.2 0.1 2.2 1 1 1 2 2 2 2 eIF-6 family CAF1 PF04857.20 KEZ44827.1 - 1.8e-24 86.5 0.0 2.8e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KEZ44827.1 - 0.027 15.1 0.0 0.5 11.0 0.0 2.4 2 0 0 2 2 2 0 RFX DNA-binding domain NDUF_B12 PF08122.12 KEZ44828.1 - 3.6e-25 87.8 1.4 4.8e-25 87.4 1.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CLTH PF10607.9 KEZ44829.1 - 1.4e-31 109.4 0.0 3.2e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain HLH PF00010.26 KEZ44830.1 - 1.1e-12 47.7 0.4 2.1e-12 46.8 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2235 PF09994.9 KEZ44832.1 - 5.8e-75 252.3 0.0 4.9e-74 249.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Aconitase PF00330.20 KEZ44833.1 - 3e-43 148.5 0.1 4e-42 144.8 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ44833.1 - 2.1e-17 63.7 0.0 3.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain OKR_DC_1_C PF03711.15 KEZ44833.1 - 0.063 13.6 0.1 0.35 11.2 0.0 2.1 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, C-terminal domain AMP-binding PF00501.28 KEZ44834.1 - 4.1e-70 236.5 0.0 5.9e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ44834.1 - 7.3e-17 62.1 2.2 1.2e-16 61.5 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.20 KEZ44834.1 - 0.11 11.9 0.1 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 LysR substrate binding domain ArAE_1_C PF11728.8 KEZ44835.1 - 0.12 12.4 0.1 0.52 10.3 0.0 1.8 1 1 1 2 2 2 0 Putative aromatic acid exporter C-terminal domain DUF966 PF06136.13 KEZ44836.1 - 0.076 12.7 0.2 0.088 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MSA-2c PF12238.8 KEZ44836.1 - 0.11 12.5 0.5 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c ADH_zinc_N_2 PF13602.6 KEZ44837.1 - 1e-08 36.3 0.0 2.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ44837.1 - 3.3e-08 33.4 0.1 1.2e-07 31.6 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_1 PF00232.18 KEZ44838.1 - 5.7e-154 512.9 0.0 7e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF4203 PF13886.6 KEZ44839.1 - 6.2e-48 163.1 23.8 8.4e-48 162.7 23.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2681 PF10883.8 KEZ44839.1 - 0.0052 17.2 1.1 0.017 15.5 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Erf4 PF10256.9 KEZ44840.1 - 7.2e-37 126.0 0.0 1.2e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PALP PF00291.25 KEZ44840.1 - 0.04 13.3 0.2 2.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme STE3 PF02076.15 KEZ44841.1 - 5.5e-59 199.8 17.2 7.4e-59 199.3 17.2 1.2 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.25 KEZ44842.1 - 5.3e-17 61.7 0.0 6.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GSH_synth_ATP PF03917.17 KEZ44843.1 - 2.6e-141 470.7 0.0 3e-141 470.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KEZ44843.1 - 1.3e-34 118.7 0.0 2.7e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 KEZ44844.1 - 4.4e-39 134.2 0.0 8e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ44844.1 - 2.7e-20 72.7 0.1 5e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ44844.1 - 0.00012 22.1 0.0 0.00042 20.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KEZ44844.1 - 0.0085 15.8 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Aminotran_1_2 PF00155.21 KEZ44845.1 - 1.1e-78 265.0 0.0 1.4e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ44845.1 - 5.1e-05 22.0 0.0 8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEZ44845.1 - 0.00046 19.3 0.0 0.0008 18.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEZ44845.1 - 0.0013 18.1 0.3 0.002 17.5 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.18 KEZ44846.1 - 0.12 12.5 9.1 0.42 10.8 9.1 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu PF17563.2 KEZ44846.1 - 1.7 8.9 4.7 21 5.4 0.1 2.3 2 0 0 2 2 2 0 Cupiennin Glyco_hydr_30_2 PF14587.6 KEZ44847.1 - 4.2e-20 72.7 1.2 4.7e-20 72.5 0.4 1.4 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 KEZ44847.1 - 7.8e-14 51.6 3.1 1.3e-13 50.9 3.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 KEZ44847.1 - 2.6e-09 37.2 3.2 7.9e-09 35.6 3.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 KEZ44847.1 - 4.3e-05 22.6 1.1 8.2e-05 21.7 1.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Levi_coat PF01819.17 KEZ44847.1 - 0.036 14.1 1.0 0.08 13.0 1.0 1.5 1 0 0 1 1 1 0 Levivirus coat protein Glyco_hydro2_C5 PF18565.1 KEZ44847.1 - 0.1 12.5 0.6 0.36 10.7 0.1 2.0 1 1 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 HK PF02110.15 KEZ44848.1 - 2.4e-72 243.3 2.3 3.3e-72 242.8 2.3 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KEZ44848.1 - 6.2e-54 182.1 0.3 5.2e-47 159.5 0.0 2.3 1 1 1 2 2 2 2 Thiamine monophosphate synthase Carb_kinase PF01256.17 KEZ44848.1 - 0.00057 19.4 0.5 0.0011 18.5 0.5 1.4 1 0 0 1 1 1 1 Carbohydrate kinase ADH_zinc_N PF00107.26 KEZ44848.1 - 0.024 14.6 2.9 0.47 10.4 0.4 3.2 4 0 0 4 4 4 0 Zinc-binding dehydrogenase Phos_pyr_kin PF08543.12 KEZ44848.1 - 0.031 13.7 0.1 0.061 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Isochorismatase PF00857.20 KEZ44849.1 - 5.1e-26 91.9 0.0 9.2e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.6 KEZ44850.1 - 9.6e-21 75.0 0.0 1.7e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ44850.1 - 2.2e-16 60.5 0.0 3.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KEZ44850.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family BP28CT PF08146.12 KEZ44853.1 - 1.9e-42 144.8 0.1 5.6e-42 143.3 0.1 1.9 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KEZ44853.1 - 1e-21 77.4 0.0 1e-21 77.4 0.0 5.0 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KEZ44853.1 - 6.1e-07 29.2 12.1 0.0031 17.6 0.0 7.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KEZ44853.1 - 0.0012 19.2 11.3 0.8 10.1 0.1 5.8 4 1 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KEZ44853.1 - 0.016 15.7 9.9 0.17 12.4 0.1 6.6 8 1 0 8 8 8 0 HEAT-like repeat RIX1 PF08167.12 KEZ44853.1 - 0.039 13.7 0.3 0.039 13.7 0.3 3.0 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Ipi1_N PF12333.8 KEZ44853.1 - 0.081 13.5 0.0 0.86 10.2 0.0 2.9 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.8 KEZ44853.1 - 0.095 12.2 0.0 0.59 9.6 0.0 2.4 1 0 0 1 1 1 0 CLASP N terminal HABP4_PAI-RBP1 PF04774.15 KEZ44854.1 - 0.22 12.4 16.4 0.083 13.7 12.3 2.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family MFS_1 PF07690.16 KEZ44855.1 - 6.2e-18 64.8 35.5 1.9e-11 43.5 7.9 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ44855.1 - 3.5e-06 26.1 0.0 0.053 12.4 0.0 2.4 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KEZ44855.1 - 0.0063 15.4 0.6 0.0063 15.4 0.6 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Phage_holin_3_6 PF07332.11 KEZ44855.1 - 0.01 15.9 0.3 0.01 15.9 0.3 4.6 5 2 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III BRI3BP PF14965.6 KEZ44855.1 - 0.04 13.4 0.2 0.04 13.4 0.2 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Actin PF00022.19 KEZ44856.1 - 4.7e-31 107.8 0.0 4.7e-20 71.6 0.0 2.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 KEZ44856.1 - 0.0036 16.2 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 KEZ44856.1 - 0.0041 16.4 0.5 0.39 9.8 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KEZ44856.1 - 0.006 17.0 0.0 0.024 15.1 0.0 2.0 1 1 0 1 1 1 1 Cell division protein FtsA DUF4451 PF14616.6 KEZ44857.1 - 2e-24 86.1 0.1 4.1e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Iso_dh PF00180.20 KEZ44858.1 - 1e-121 406.4 0.0 1.5e-121 405.8 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.29 KEZ44858.1 - 2.6e-08 33.6 6.2 4.3e-08 32.9 6.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KEZ44858.1 - 0.12 11.9 1.5 0.22 11.1 1.5 1.4 1 0 0 1 1 1 0 PHD-finger EVE PF01878.18 KEZ44859.1 - 2.8e-48 163.6 0.3 2.8e-48 163.6 0.3 2.0 2 0 0 2 2 2 1 EVE domain RNA_pol_Rbc25 PF08292.12 KEZ44859.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.6 2 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 SSrecog PF03531.14 KEZ44860.1 - 1.7e-30 104.7 0.1 8.7e-30 102.5 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KEZ44860.1 - 2.5e-30 104.7 0.5 8.4e-29 99.8 0.1 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KEZ44860.1 - 3.8e-23 81.7 0.0 3.2e-22 78.7 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like YL1 PF05764.13 KEZ44860.1 - 0.9 9.6 23.3 1.5 8.9 23.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein RNA_polI_A34 PF08208.11 KEZ44860.1 - 2.2 8.3 15.6 0.17 12.0 10.8 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2201_N PF13203.6 KEZ44860.1 - 2.9 7.4 10.1 0.84 9.2 0.1 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain SDA1 PF05285.12 KEZ44860.1 - 6.9 6.0 23.6 10 5.4 23.6 1.3 1 0 0 1 1 1 0 SDA1 Mg_trans_NIPA PF05653.14 KEZ44861.1 - 5.6e-58 196.4 14.4 3e-55 187.4 11.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA CD20 PF04103.15 KEZ44861.1 - 0.0098 16.0 2.8 1.6 8.8 0.2 3.1 3 0 0 3 3 3 2 CD20-like family EamA PF00892.20 KEZ44861.1 - 0.016 15.4 1.0 0.016 15.4 1.0 3.9 3 1 1 4 4 4 0 EamA-like transporter family LRR19-TM PF15176.6 KEZ44861.1 - 0.091 12.8 4.0 0.25 11.3 0.0 3.1 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Ctr PF04145.15 KEZ44861.1 - 0.52 10.9 6.7 4.7 7.8 0.1 3.8 3 2 1 4 4 4 0 Ctr copper transporter family LysE PF01810.18 KEZ44861.1 - 1.9 7.9 13.6 0.022 14.2 3.8 2.5 2 1 1 3 3 3 0 LysE type translocator DUF2101 PF09874.9 KEZ44861.1 - 2.7 7.7 8.0 3.4 7.3 5.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2101) DUF4131 PF13567.6 KEZ44861.1 - 4.1 7.0 11.5 1.8 8.2 0.5 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF1461 PF07314.11 KEZ44861.1 - 9.6 6.1 8.6 1.6 8.6 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Cnd3 PF12719.7 KEZ44862.1 - 1.9e-93 312.9 1.1 1.9e-93 312.9 1.1 2.4 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KEZ44862.1 - 1.9e-11 44.2 10.9 3.2e-06 27.4 3.0 4.8 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.22 KEZ44862.1 - 3.3e-08 33.1 11.6 0.18 12.1 0.0 7.3 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 KEZ44862.1 - 0.0031 17.6 2.8 0.52 10.3 0.1 4.2 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 KEZ44862.1 - 0.013 15.0 1.9 0.91 9.0 0.1 3.0 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 KEZ44862.1 - 0.59 10.7 14.9 2.5 8.7 1.1 6.2 6 1 1 7 7 7 0 HEAT-like repeat Phosphodiest PF01663.22 KEZ44863.1 - 1.3e-12 48.0 0.9 5.7e-10 39.3 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KEZ44863.1 - 0.00032 20.2 0.0 0.0015 18.0 0.0 2.0 2 1 0 2 2 2 1 Sulfatase MHYT PF03707.16 KEZ44863.1 - 0.01 16.0 4.8 3.8 7.7 0.0 4.1 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat Metalloenzyme PF01676.18 KEZ44863.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF2423 PF10338.9 KEZ44864.1 - 3e-20 72.2 4.0 3e-20 72.2 4.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2423) Myb_Cef PF11831.8 KEZ44864.1 - 0.031 13.9 4.2 0.035 13.7 4.2 1.1 1 0 0 1 1 1 0 pre-mRNA splicing factor component HMG14_17 PF01101.18 KEZ44864.1 - 0.068 14.1 6.7 0.1 13.6 6.3 1.7 1 1 0 1 1 1 0 HMG14 and HMG17 P53_C PF11619.8 KEZ44864.1 - 0.25 11.4 0.2 0.25 11.4 0.2 2.0 2 1 0 2 2 2 0 Transcription factor P53 - C terminal domain TRAPP PF04051.16 KEZ44865.1 - 6.7e-43 145.9 0.0 8.7e-43 145.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_C PF02866.18 KEZ44866.1 - 7e-48 162.7 0.0 9.9e-48 162.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KEZ44866.1 - 1.1e-43 148.7 0.2 1.7e-43 148.1 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEZ44866.1 - 0.0091 15.0 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.17 KEZ44867.1 - 5.3e-34 117.4 0.4 6.5e-34 117.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family FA_hydroxylase PF04116.13 KEZ44868.1 - 1.1e-24 87.3 17.7 1.1e-24 87.3 17.7 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.32 KEZ44869.1 - 1.2e-59 196.8 14.0 7.9e-09 36.0 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KEZ44869.1 - 9.2e-17 61.1 11.2 1.9e-16 60.1 11.2 1.5 1 1 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KEZ44869.1 - 3e-16 59.5 0.0 0.0003 21.0 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ44869.1 - 2e-07 30.3 0.1 0.24 10.3 0.0 4.9 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KEZ44869.1 - 1.3e-05 24.7 0.0 0.16 11.3 0.0 4.5 4 1 1 5 5 5 2 WD40-like domain Cytochrom_D1 PF02239.16 KEZ44869.1 - 0.00052 18.7 0.3 0.07 11.6 0.1 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.8 KEZ44869.1 - 0.0033 16.1 0.2 1.5 7.3 0.0 3.5 1 1 3 4 4 4 1 Nucleoporin Nup120/160 Filament PF00038.21 KEZ44869.1 - 0.023 14.3 2.0 0.034 13.7 2.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein Golgin_A5 PF09787.9 KEZ44869.1 - 0.026 14.0 3.8 0.039 13.4 3.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 PD40 PF07676.12 KEZ44869.1 - 0.036 14.0 0.0 21 5.2 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat SHE3 PF17078.5 KEZ44869.1 - 0.084 12.6 2.2 0.14 11.9 2.2 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nucleoporin_N PF08801.11 KEZ44869.1 - 0.095 11.4 0.1 5.9 5.5 0.0 3.3 2 1 1 3 3 3 0 Nup133 N terminal like TSNAXIP1_N PF15739.5 KEZ44869.1 - 0.18 12.2 4.9 0.3 11.5 4.9 1.2 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus MMS1_N PF10433.9 KEZ44869.1 - 0.18 10.4 0.0 2.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term TPX2 PF06886.11 KEZ44869.1 - 4.1 7.7 9.2 7.2 6.9 5.2 2.7 2 1 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) OAD_gamma PF04277.13 KEZ44870.1 - 2.8 8.6 0.0 2.8 8.6 0.0 2.7 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Aa_trans PF01490.18 KEZ44871.1 - 3.5e-58 197.3 24.7 4.5e-58 196.9 24.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 KEZ44871.1 - 2.3e-06 26.7 11.9 2.3e-06 26.7 11.9 2.0 2 0 0 2 2 2 1 Amino acid permease Hydrolase PF00702.26 KEZ44872.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Bmt2 PF11968.8 KEZ44873.1 - 1.7e-57 194.8 0.0 1.6e-50 172.0 0.0 2.1 1 1 1 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KEZ44873.1 - 0.0057 16.5 0.0 0.0078 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF1590 PF07629.11 KEZ44873.1 - 0.33 10.8 0.1 0.33 10.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) Ribosomal_L23eN PF03939.13 KEZ44874.1 - 1.9e-24 85.6 11.2 4.7e-24 84.3 11.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KEZ44874.1 - 5.3e-15 55.5 0.4 5.3e-15 55.5 0.4 1.8 3 0 0 3 3 3 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 KEZ44875.1 - 3.1e-19 68.4 0.2 3.9e-19 68.1 0.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CorA PF01544.18 KEZ44876.1 - 1.6e-42 145.8 0.1 4.6e-42 144.3 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SPC12 PF06645.13 KEZ44877.1 - 3.6e-28 97.4 0.1 4.1e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.7 KEZ44878.1 - 7.4e-25 87.0 12.9 9.9e-25 86.6 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KEZ44878.1 - 1.1e-16 60.6 9.6 1.4e-16 60.3 9.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KEZ44878.1 - 3.9e-06 27.1 14.1 0.00014 22.1 14.1 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEZ44878.1 - 0.0016 18.2 14.3 0.0025 17.6 8.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ44878.1 - 0.0017 18.2 11.6 0.03 14.2 11.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEZ44878.1 - 0.21 11.5 10.8 0.65 9.9 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEZ44878.1 - 0.32 10.8 15.8 26 4.7 15.8 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KEZ44878.1 - 0.41 10.7 6.8 1.5 8.9 6.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KEZ44878.1 - 1.4 8.6 15.0 0.33 10.6 4.9 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KEZ44878.1 - 1.9 8.7 10.4 5 7.4 9.3 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 KEZ44878.1 - 6.1 6.9 12.1 54 3.9 12.1 2.5 1 1 0 1 1 1 0 zinc-RING finger domain Tyr-DNA_phospho PF06087.12 KEZ44879.1 - 5.6e-46 157.3 1.0 1.2e-16 60.7 0.0 3.6 2 1 1 4 4 4 3 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KEZ44879.1 - 3e-05 23.6 0.1 7.5e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Ndc1_Nup PF09531.10 KEZ44879.1 - 0.02 13.6 4.3 0.024 13.3 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDP-OH_P_transf PF01066.21 KEZ44880.1 - 5.9e-15 55.8 0.3 5.9e-15 55.8 0.3 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.22 KEZ44881.1 - 4.7e-151 503.3 0.0 6.8e-151 502.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Sec1 PF00995.23 KEZ44881.1 - 3.3e-129 432.8 0.3 4.5e-129 432.3 0.3 1.1 1 0 0 1 1 1 1 Sec1 family GIDA_assoc PF13932.6 KEZ44881.1 - 8.9e-66 222.1 0.0 2.3e-65 220.7 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KEZ44881.1 - 2.9e-06 26.9 0.3 5e-06 26.1 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ44881.1 - 3.4e-06 26.5 0.3 9.7e-06 25.0 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ44881.1 - 0.011 14.9 6.8 0.022 13.8 5.7 2.1 1 1 1 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 KEZ44881.1 - 0.048 13.0 0.1 0.094 12.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MGS PF02142.22 KEZ44881.1 - 0.1 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 MGS-like domain HI0933_like PF03486.14 KEZ44881.1 - 8.8 4.9 8.5 0.18 10.4 0.8 2.1 4 0 0 4 4 4 0 HI0933-like protein Synaptobrevin PF00957.21 KEZ44882.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Synaptobrevin MBOAT PF03062.19 KEZ44883.1 - 4.1e-56 190.8 1.5 4.1e-56 190.8 1.5 2.4 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family UAA PF08449.11 KEZ44883.1 - 1.7e-09 37.3 13.5 3.2e-09 36.4 13.5 1.4 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEZ44883.1 - 7.2e-05 23.0 9.6 7.2e-05 23.0 9.6 4.1 4 0 0 4 4 4 2 EamA-like transporter family SpecificRecomb PF10136.9 KEZ44883.1 - 0.063 11.6 0.1 0.14 10.5 0.1 1.5 1 0 0 1 1 1 0 Site-specific recombinase ARD PF03079.14 KEZ44884.1 - 3.4e-33 115.1 0.2 3.4e-33 115.1 0.2 1.6 2 0 0 2 2 2 1 ARD/ARD' family adh_short PF00106.25 KEZ44884.1 - 5.5e-30 104.3 0.0 9.4e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ44884.1 - 2.3e-20 73.2 0.0 3.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ44884.1 - 4.7e-09 36.4 0.0 1.3e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Cupin_2 PF07883.11 KEZ44884.1 - 1.9e-07 30.7 0.1 4.5e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Epimerase PF01370.21 KEZ44884.1 - 1.9e-06 27.5 0.1 4.3e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AraC_binding PF02311.19 KEZ44884.1 - 1.4e-05 25.0 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain RmlD_sub_bind PF04321.17 KEZ44884.1 - 0.00059 19.0 0.0 0.0016 17.6 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEZ44884.1 - 0.0069 15.4 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ44884.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KEZ44884.1 - 0.049 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 KEZ44884.1 - 0.16 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Creatinase_N_2 PF16189.5 KEZ44885.1 - 4.5e-52 176.4 0.0 3.3e-50 170.3 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KEZ44885.1 - 8.3e-46 156.3 0.0 1.3e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KEZ44885.1 - 9.4e-22 76.9 0.2 2.9e-21 75.3 0.2 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KEZ44885.1 - 5.3e-17 62.7 0.1 1.4e-15 58.1 0.0 2.6 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain SBP_bac_8 PF13416.6 KEZ44885.1 - 0.13 12.0 0.1 2.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Importin_rep_3 PF18806.1 KEZ44886.1 - 0.0026 17.8 0.0 0.0087 16.1 0.0 1.9 1 0 0 1 1 1 1 Importin 13 repeat tRNA-synt_1b PF00579.25 KEZ44887.1 - 6.4e-40 137.3 0.0 8.2e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Fcf2 PF08698.11 KEZ44888.1 - 4.6e-31 107.1 0.0 9.9e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.22 KEZ44888.1 - 1.1e-20 73.6 0.0 2.4e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CBFD_NFYB_HMF PF00808.23 KEZ44889.1 - 2.7e-19 69.2 0.5 4.1e-19 68.6 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KEZ44889.1 - 6.5e-15 55.7 0.1 1e-14 55.0 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KEZ44889.1 - 0.047 14.0 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.12 KEZ44890.1 - 2.3e-113 378.8 1.1 2.3e-113 378.8 1.1 2.7 2 1 1 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.6 KEZ44890.1 - 0.0066 16.2 4.3 0.01 15.6 3.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Rbsn PF11464.8 KEZ44890.1 - 0.18 11.6 2.6 0.21 11.3 0.5 2.3 2 0 0 2 2 2 0 Rabenosyn Rab binding domain COG5 PF10392.9 KEZ44890.1 - 0.21 11.8 8.3 3 8.0 5.0 3.3 3 0 0 3 3 3 0 Golgi transport complex subunit 5 STAT1_TAZ2bind PF12162.8 KEZ44890.1 - 0.64 9.7 2.5 7.2 6.3 0.1 3.0 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain COG2 PF06148.11 KEZ44890.1 - 6.6 6.8 9.8 3 7.9 3.5 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_2 PF04059.12 KEZ44891.1 - 2.8e-18 65.9 0.6 3.8e-11 43.1 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif 2 RRM_occluded PF16842.5 KEZ44891.1 - 0.17 11.8 0.0 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Aldo_ket_red PF00248.21 KEZ44892.1 - 2.7e-56 191.0 0.0 3.1e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MerR_1 PF13411.6 KEZ44892.1 - 0.025 14.7 0.0 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 MerR HTH family regulatory protein Lipase_GDSL_2 PF13472.6 KEZ44893.1 - 3.2e-05 24.4 0.1 0.00015 22.3 0.0 1.8 1 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF1345 PF07077.11 KEZ44893.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Ank_2 PF12796.7 KEZ44894.1 - 3.1e-28 98.2 0.4 2.9e-12 47.0 0.1 3.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ44894.1 - 5.5e-27 93.8 1.9 2.6e-10 40.6 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ44894.1 - 1.1e-23 80.7 0.6 9.7e-05 22.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 KEZ44894.1 - 5.1e-19 67.8 2.6 0.0015 18.9 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 KEZ44894.1 - 1.6e-18 66.5 0.2 0.00011 22.4 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ44895.1 - 1.5e-05 25.0 0.3 0.00013 21.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ44895.1 - 7.9e-05 23.1 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KEZ44895.1 - 0.00092 19.6 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KEZ44895.1 - 0.0029 18.0 0.1 0.0053 17.1 0.1 1.4 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KEZ44895.1 - 0.0058 16.4 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ44895.1 - 0.0067 15.6 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEZ44895.1 - 0.0089 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KEZ44895.1 - 0.01 15.8 0.7 0.66 10.0 0.0 2.8 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 KEZ44895.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KEZ44895.1 - 0.024 15.0 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KEZ44895.1 - 0.027 15.0 0.1 0.05 14.1 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.11 KEZ44895.1 - 0.029 14.5 0.1 0.048 13.8 0.1 1.4 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.6 KEZ44895.1 - 0.039 14.2 0.1 0.063 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KEZ44895.1 - 0.047 13.9 0.1 0.068 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KEZ44895.1 - 0.087 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 KEZ44895.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KEZ44895.1 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF981 PF06168.11 KEZ44897.1 - 0.33 10.8 15.4 0.098 12.6 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF981) Hint_2 PF13403.6 KEZ44899.1 - 0.0012 19.1 0.1 0.015 15.6 0.1 2.4 2 0 0 2 2 2 1 Hint domain CAAD PF14159.6 KEZ44899.1 - 0.051 13.4 1.7 0.14 12.0 1.7 1.7 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase LigA PF07746.11 KEZ44899.1 - 0.19 11.9 1.0 0.38 10.9 0.1 1.9 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit DUF3040 PF11239.8 KEZ44899.1 - 0.32 11.3 3.2 1.2 9.4 3.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) ABC2_membrane PF01061.24 KEZ44900.1 - 3e-83 278.4 47.0 4.4e-47 160.2 13.3 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ44900.1 - 1.1e-38 132.8 0.0 1.1e-18 68.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEZ44900.1 - 2.5e-25 88.2 1.6 8.4e-22 76.9 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KEZ44900.1 - 1e-07 31.4 34.2 0.00011 21.5 11.0 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KEZ44900.1 - 3.6e-06 27.5 0.1 0.0032 17.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 KEZ44900.1 - 0.00026 21.6 0.0 0.00085 19.9 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KEZ44900.1 - 0.00027 20.9 0.1 0.019 14.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KEZ44900.1 - 0.0011 18.6 0.0 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEZ44900.1 - 0.0013 18.7 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ44900.1 - 0.0035 17.1 0.4 0.13 12.0 0.2 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ44900.1 - 0.011 15.9 0.1 1.1 9.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEZ44900.1 - 0.014 15.7 1.1 0.96 9.7 0.5 2.9 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.12 KEZ44900.1 - 0.018 14.8 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KEZ44900.1 - 0.036 13.4 0.0 0.93 8.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 KEZ44900.1 - 0.037 13.7 0.2 3.8 7.2 0.7 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEZ44900.1 - 0.046 13.8 0.1 17 5.6 0.2 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KEZ44900.1 - 0.065 13.8 0.0 5 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2627 PF11118.8 KEZ44900.1 - 0.089 13.4 0.2 0.46 11.1 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) PduV-EutP PF10662.9 KEZ44900.1 - 0.15 11.8 0.4 2.7 7.7 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KEZ44900.1 - 0.17 11.4 0.8 4.8 6.7 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEZ44900.1 - 0.33 10.9 0.7 5 7.0 0.6 2.4 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.25 KEZ44901.1 - 5e-20 72.0 0.0 1.6e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44901.1 - 4.5e-15 55.6 0.0 6.2e-14 51.9 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ44901.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MaoC_dehydrat_N PF13452.6 KEZ44902.1 - 0.00024 21.2 0.0 0.0084 16.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 KEZ44902.1 - 0.017 14.7 0.1 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 MaoC like domain Fungal_trans PF04082.18 KEZ44903.1 - 2.2e-12 46.6 0.0 1.2e-08 34.3 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 KEZ44905.1 - 4.6e-43 147.5 0.0 8.4e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ44905.1 - 1.3e-30 106.8 0.0 6.4e-29 101.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ44905.1 - 1.6e-20 72.9 0.1 3.3e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Aldolase_II PF00596.21 KEZ44906.1 - 7.2e-44 149.9 0.0 9.3e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MinC_C PF03775.16 KEZ44906.1 - 0.16 11.9 0.6 0.42 10.6 0.6 1.6 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Oxidored_FMN PF00724.20 KEZ44909.1 - 4.3e-61 207.1 0.0 5.3e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CFTR_R PF14396.6 KEZ44911.1 - 0.03 13.9 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain AMP-binding PF00501.28 KEZ44912.1 - 2.3e-45 155.0 0.0 3.1e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KEZ44912.1 - 3.7e-07 30.0 0.1 7.9e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KEZ44912.1 - 0.00094 20.1 0.0 0.0019 19.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KEZ44913.1 - 3.5e-16 59.0 0.2 1.1e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 KEZ44914.1 - 2.3e-24 86.1 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44914.1 - 5.5e-15 55.8 0.0 2.2e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44914.1 - 1.8e-13 50.9 0.0 4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44914.1 - 1.8e-10 41.4 0.0 1.9e-09 38.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44914.1 - 2.4e-09 37.2 0.0 0.0023 17.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44914.1 - 2e-05 24.0 0.0 0.00063 19.1 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ44914.1 - 0.00022 20.8 0.0 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KEZ44914.1 - 0.0037 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEZ44914.1 - 0.0095 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KEZ44914.1 - 0.05 13.1 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.12 KEZ44914.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KEZ44914.1 - 0.087 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MARVEL PF01284.23 KEZ44915.1 - 0.72 9.9 8.5 4.3 7.4 8.5 2.1 1 1 0 1 1 1 0 Membrane-associating domain Methyltransf_23 PF13489.6 KEZ44916.1 - 2.8e-20 72.8 0.0 4.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44916.1 - 4.9e-12 45.9 0.0 7.6e-11 42.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44916.1 - 1.4e-11 45.0 0.0 3.2e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44916.1 - 6.1e-09 36.4 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44916.1 - 2.1e-06 28.4 0.0 1.5e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ44916.1 - 0.0006 19.4 0.0 0.0025 17.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ44916.1 - 0.0017 17.8 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 KEZ44916.1 - 0.0059 16.7 0.0 0.0095 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KEZ44916.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEZ44916.1 - 0.034 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase CheR PF01739.18 KEZ44916.1 - 0.05 13.1 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 KEZ44916.1 - 0.12 11.7 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KEZ44916.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_23 PF13489.6 KEZ44917.1 - 7.5e-15 55.1 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44917.1 - 3.2e-11 43.3 0.0 2e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44917.1 - 1.7e-09 38.3 0.0 3.6e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44917.1 - 8.9e-07 29.5 0.0 2.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44917.1 - 3.5e-06 27.7 0.0 2.4e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ44917.1 - 0.00092 18.8 0.0 0.0021 17.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KEZ44917.1 - 0.011 15.1 0.0 0.79 9.0 0.0 2.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KEZ44917.1 - 0.023 14.0 0.0 0.053 12.8 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain FtsJ PF01728.19 KEZ44917.1 - 0.027 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KEZ44917.1 - 0.042 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KEZ44917.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase GidB PF02527.15 KEZ44917.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF3488 PF11992.8 KEZ44918.1 - 3.9 6.3 13.2 0.043 12.8 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) HET PF06985.11 KEZ44919.1 - 1.1e-32 113.4 0.0 2.2e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 KEZ44919.1 - 2.6e-30 105.7 0.0 4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ44919.1 - 4.6e-22 78.8 0.0 9.1e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ44919.1 - 2.2e-05 24.1 0.0 6.3e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEZ44919.1 - 0.00028 21.1 0.0 0.00059 20.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Nop10p PF04135.12 KEZ44919.1 - 0.13 12.3 0.2 0.3 11.2 0.2 1.6 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family adh_short PF00106.25 KEZ44920.1 - 2.3e-22 79.4 0.3 1.7e-21 76.6 0.3 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ44920.1 - 7.6e-11 42.0 0.2 1.9e-10 40.7 0.1 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ44920.1 - 5.1e-08 33.0 0.6 8.5e-08 32.3 0.1 1.5 2 0 0 2 2 2 1 KR domain YAcAr PF10686.9 KEZ44920.1 - 0.14 12.1 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family adh_short_C2 PF13561.6 KEZ44921.1 - 2.9e-65 220.1 0.9 3.5e-65 219.8 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ44921.1 - 4.9e-48 163.2 1.1 6.3e-48 162.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ44921.1 - 6.7e-08 32.6 0.1 1.3e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ44921.1 - 2.5e-05 23.9 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KEZ44921.1 - 0.0015 18.8 0.1 0.0028 17.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KEZ44921.1 - 0.057 13.3 0.1 0.08 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 KEZ44921.1 - 0.075 13.7 0.1 0.69 10.6 0.0 2.2 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KEZ44922.1 - 1.1e-16 60.6 0.1 2.6e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KEZ44923.1 - 5.8e-80 269.4 20.7 6.9e-80 269.1 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ44923.1 - 1.7e-25 89.7 51.2 1.9e-19 69.8 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KEZ44923.1 - 0.00075 17.9 1.3 0.0013 17.1 1.3 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) ABC2_membrane_2 PF12679.7 KEZ44923.1 - 0.015 14.6 3.5 0.035 13.4 3.5 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein GET2 PF08690.10 KEZ44923.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Aldedh PF00171.22 KEZ44924.1 - 2.4e-128 428.6 0.0 2.1e-116 389.2 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family SNF2_N PF00176.23 KEZ44925.1 - 3.7e-34 118.0 0.1 1.6e-32 112.6 0.0 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ44925.1 - 1.6e-12 47.7 0.0 3.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NACHT PF05729.12 KEZ44926.1 - 1.5e-10 41.2 0.0 3.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KEZ44926.1 - 4.4e-06 27.2 0.0 1.3e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KEZ44926.1 - 3.8e-05 23.7 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KEZ44926.1 - 0.00024 21.4 0.0 0.0011 19.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KEZ44926.1 - 0.00069 19.0 0.0 0.0017 17.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 KEZ44926.1 - 0.0026 17.0 0.0 0.0053 16.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KEZ44926.1 - 0.0036 17.7 1.0 0.022 15.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KEZ44926.1 - 0.0051 17.0 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KEZ44926.1 - 0.043 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Goodbye PF17109.5 KEZ44926.1 - 0.056 13.9 0.3 0.13 12.7 0.3 1.7 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain cobW PF02492.19 KEZ44926.1 - 0.074 12.6 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 KEZ44926.1 - 0.076 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ44926.1 - 0.083 12.2 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 KEZ44926.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB COG2 PF06148.11 KEZ44926.1 - 0.87 9.7 4.8 7.7 6.6 1.0 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cellulase PF00150.18 KEZ44927.1 - 3e-13 49.8 0.0 2.2e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KEZ44927.1 - 6.9e-08 32.0 0.0 4.1e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KEZ44927.1 - 0.00016 21.4 0.6 0.00024 20.9 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KEZ44927.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Helo_like_N PF17111.5 KEZ44929.1 - 3.4e-81 271.6 5.2 9.2e-73 244.0 0.3 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KEZ44929.1 - 2e-05 24.7 3.3 0.00036 20.7 0.0 3.2 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ArgoL1 PF08699.10 KEZ44929.1 - 0.029 14.0 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Argonaute linker 1 domain DUF1128 PF06569.11 KEZ44929.1 - 0.036 14.1 0.3 0.28 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) MalF_P2 PF14785.6 KEZ44929.1 - 0.21 11.6 1.9 0.33 11.0 0.2 2.0 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain Syntaxin-6_N PF09177.11 KEZ44929.1 - 0.23 12.0 5.2 0.34 11.5 0.5 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal FlxA PF14282.6 KEZ44929.1 - 1.8 8.6 8.8 8.7 6.4 1.3 3.1 3 0 0 3 3 3 0 FlxA-like protein DUF842 PF05811.13 KEZ44929.1 - 1.8 8.3 15.6 4.1 7.1 6.9 3.6 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) YlqD PF11068.8 KEZ44929.1 - 3.5 8.0 12.7 0.28 11.6 3.1 2.7 3 0 0 3 3 3 0 YlqD protein Abhydrolase_1 PF00561.20 KEZ44930.1 - 6.1e-15 55.5 0.1 5.3e-14 52.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ44930.1 - 1.8e-11 43.8 0.0 3.8e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ44930.1 - 2.5e-10 41.3 3.2 4.5e-10 40.5 3.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEZ44930.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 KEZ44932.1 - 1.2e-10 40.8 0.4 2.3e-10 39.9 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dynamin_N PF00350.23 KEZ44934.1 - 1.3e-27 96.9 0.0 4e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KEZ44934.1 - 5.9e-19 68.4 0.0 9.2e-15 54.6 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KEZ44934.1 - 0.00045 20.3 0.0 0.0031 17.6 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ44934.1 - 0.1 13.0 0.0 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 KEZ44934.1 - 0.14 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Methyltransf_23 PF13489.6 KEZ44935.1 - 1.1e-18 67.6 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44935.1 - 2.4e-13 50.6 0.0 7.2e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44935.1 - 1.6e-10 41.0 0.0 2.7e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44935.1 - 2.3e-10 41.0 0.0 9.4e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44935.1 - 1.8e-09 38.2 0.0 8e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44935.1 - 4.9e-06 26.1 0.0 0.00012 21.6 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ44935.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ44935.1 - 0.00019 21.0 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ44935.1 - 0.00027 20.5 0.0 0.0018 17.8 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KEZ44935.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KEZ44935.1 - 0.025 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KEZ44935.1 - 0.049 12.9 0.0 0.099 11.9 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase HET PF06985.11 KEZ44936.1 - 3.2e-34 118.4 0.0 6.9e-34 117.3 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3050 PF11251.8 KEZ44937.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Glyco_hydro_7 PF00840.20 KEZ44939.1 - 7.6e-83 278.6 18.5 4.1e-46 157.6 7.5 5.1 1 1 2 3 3 3 3 Glycosyl hydrolase family 7 SesA PF17107.5 KEZ44939.1 - 5.2e-40 136.4 0.3 1.5e-39 135.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KEZ44939.1 - 0.00041 20.6 0.0 0.0012 19.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 KEZ44939.1 - 0.0095 16.5 0.1 0.034 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KEZ44939.1 - 0.011 16.3 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 KEZ44939.1 - 0.03 14.7 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 KEZ44939.1 - 0.04 13.8 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KEZ44939.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 KEZ44939.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KEZ44939.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KEZ44939.1 - 0.11 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KEZ44939.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Striatin PF08232.12 KEZ44940.1 - 4.7e-05 24.0 1.1 5.9e-05 23.7 1.1 1.2 1 0 0 1 1 1 1 Striatin family CENP-F_leu_zip PF10473.9 KEZ44940.1 - 0.0033 17.5 0.2 0.0062 16.6 0.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 KEZ44940.1 - 0.0035 17.4 10.1 0.0073 16.4 10.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper CCD48 PF15799.5 KEZ44940.1 - 0.0057 15.0 2.2 0.006 14.9 2.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 Tropomyosin PF00261.20 KEZ44940.1 - 0.0085 15.5 2.2 0.011 15.1 2.2 1.2 1 0 0 1 1 1 1 Tropomyosin Herpes_UL25 PF01499.16 KEZ44940.1 - 0.015 13.9 2.2 0.018 13.6 2.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family bZIP_1 PF00170.21 KEZ44940.1 - 0.031 14.4 8.6 1.5 9.0 9.4 2.3 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 KEZ44940.1 - 0.071 13.6 0.5 0.071 13.6 0.5 1.9 2 0 0 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 KEZ44940.1 - 0.11 12.6 0.8 0.18 11.8 0.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 KEZ44940.1 - 0.11 13.0 5.1 0.17 12.3 5.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ParcG PF10274.9 KEZ44940.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Parkin co-regulated protein DUF724 PF05266.14 KEZ44940.1 - 0.17 11.7 1.3 0.26 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KEZ44940.1 - 0.19 11.8 0.4 0.29 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4337 PF14235.6 KEZ44940.1 - 0.38 10.8 2.9 0.55 10.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Neprosin_AP PF14365.6 KEZ44940.1 - 0.43 11.1 0.1 0.43 11.1 0.1 2.1 1 1 1 2 2 2 0 Neprosin activation peptide MFS_1 PF07690.16 KEZ44945.1 - 6.8e-20 71.3 17.5 2.9e-18 65.9 19.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KEZ44946.1 - 1.3e-09 37.5 0.0 2.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ44946.1 - 9.8e-05 22.4 13.9 0.00012 22.1 9.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKS_DE PF18369.1 KEZ44946.1 - 0.044 14.4 0.8 2.6 8.7 0.2 2.9 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Sugar_tr PF00083.24 KEZ44947.1 - 1e-85 288.3 24.3 1.2e-85 288.1 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ44947.1 - 7.5e-24 84.3 28.9 7.5e-24 84.3 28.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 KEZ44948.1 - 1.9e-53 181.5 0.0 4.2e-53 180.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ44948.1 - 5e-49 167.4 0.0 8.9e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ44948.1 - 2.6e-18 65.9 0.0 8.4e-18 64.2 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KEZ44948.1 - 0.00027 20.8 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Diphtheria_C PF02763.14 KEZ44948.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Diphtheria toxin, C domain Sugar-bind PF04198.13 KEZ44948.1 - 0.2 10.8 0.2 0.51 9.4 0.0 1.6 2 0 0 2 2 2 0 Putative sugar-binding domain F-box-like PF12937.7 KEZ44949.1 - 1.7e-06 27.8 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KEZ44949.1 - 0.0043 16.9 0.1 0.0099 15.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain HI0933_like PF03486.14 KEZ44950.1 - 0.44 9.2 0.8 1.1 7.9 0.9 1.5 2 0 0 2 2 2 0 HI0933-like protein Aa_trans PF01490.18 KEZ44951.1 - 3.1e-36 125.0 30.9 3.5e-36 124.8 30.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.21 KEZ44951.1 - 4.3 7.0 21.3 0.059 13.1 4.5 2.9 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus 7tm_7 PF08395.12 KEZ44951.1 - 7.6 5.6 21.4 0.037 13.3 1.3 3.4 2 1 1 3 3 3 0 7tm Chemosensory receptor Aldedh PF00171.22 KEZ44952.1 - 4.4e-134 447.5 0.2 5e-134 447.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1344 PF07076.11 KEZ44952.1 - 0.093 12.7 0.0 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) DUF3879 PF12995.7 KEZ44952.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) FMN_dh PF01070.18 KEZ44953.1 - 3.4e-117 391.4 0.0 4.1e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KEZ44953.1 - 4.9e-06 25.8 0.3 1.2e-05 24.5 0.3 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEZ44953.1 - 0.00043 19.5 0.1 0.00092 18.4 0.1 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KEZ44953.1 - 0.00071 19.1 0.1 0.0099 15.4 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 KEZ44953.1 - 0.0014 18.1 0.4 0.002 17.5 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 KEZ44953.1 - 0.016 14.4 0.1 0.036 13.3 0.1 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 KEZ44953.1 - 0.017 14.4 0.0 0.83 8.9 0.0 2.9 3 0 0 3 3 3 0 Thiamine monophosphate synthase ThiG PF05690.14 KEZ44953.1 - 0.054 12.8 0.2 0.6 9.4 0.0 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 KEZ44953.1 - 0.16 11.1 0.0 1.9 7.5 0.0 2.4 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) Fungal_trans_2 PF11951.8 KEZ44954.1 - 2.7e-48 164.7 0.2 3.7e-48 164.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 KEZ44955.1 - 5.7e-110 367.8 0.0 8e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III NAD_binding_10 PF13460.6 KEZ44955.1 - 5.8e-07 29.6 0.0 2.2e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KEZ44955.1 - 6.4e-06 25.9 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KEZ44955.1 - 0.00013 21.5 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEZ44955.1 - 0.0057 15.8 0.0 0.0097 15.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Aldedh PF00171.22 KEZ44956.1 - 2.6e-159 530.6 0.1 4.1e-159 530.0 0.1 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family APH PF01636.23 KEZ44956.1 - 3e-12 47.0 0.0 1.9e-11 44.3 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family LuxC PF05893.14 KEZ44956.1 - 0.0003 20.0 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Choline_kinase PF01633.20 KEZ44956.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1487 PF07368.11 KEZ44956.1 - 0.019 14.4 0.0 0.1 12.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) HET-s_218-289 PF11558.8 KEZ44956.1 - 0.18 11.9 0.3 1.5 8.9 0.0 2.5 3 0 0 3 3 3 0 Het-s 218-289 DNA_pol3_theta PF06440.11 KEZ44957.1 - 0.43 10.3 2.7 0.8 9.4 0.0 2.8 4 0 0 4 4 4 0 DNA polymerase III, theta subunit Nop14 PF04147.12 KEZ44958.1 - 0.0019 16.5 8.2 0.0024 16.2 8.2 1.1 1 0 0 1 1 1 1 Nop14-like family TFIIF_alpha PF05793.12 KEZ44958.1 - 0.0035 16.0 8.2 0.0048 15.5 8.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sigma70_ner PF04546.13 KEZ44958.1 - 0.0043 17.0 5.6 0.0063 16.4 5.6 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Myc_N PF01056.18 KEZ44958.1 - 0.0051 16.8 7.8 0.0078 16.1 7.8 1.2 1 0 0 1 1 1 1 Myc amino-terminal region CENP-N PF05238.13 KEZ44958.1 - 0.01 15.2 2.1 0.014 14.7 2.1 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Pox_Ag35 PF03286.14 KEZ44958.1 - 0.017 15.0 6.5 0.026 14.3 6.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 KEZ44958.1 - 0.02 14.5 5.9 0.037 13.7 5.9 1.4 1 0 0 1 1 1 0 FAM176 family Dicty_REP PF05086.12 KEZ44958.1 - 0.035 12.1 3.9 0.046 11.7 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SDA1 PF05285.12 KEZ44958.1 - 0.055 12.9 11.6 0.079 12.4 11.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KEZ44958.1 - 0.081 11.2 10.6 0.12 10.7 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KEZ44958.1 - 0.089 12.1 10.0 0.19 11.0 10.0 1.5 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KEZ44958.1 - 0.1 10.6 7.3 0.14 10.2 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PTPRCAP PF15713.5 KEZ44958.1 - 0.12 12.7 12.8 0.21 11.9 12.8 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SMN PF06003.12 KEZ44958.1 - 0.13 11.5 3.7 0.2 10.9 3.7 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4746 PF15928.5 KEZ44958.1 - 0.13 11.7 10.8 0.18 11.2 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF719 PF05334.13 KEZ44958.1 - 0.18 12.0 5.2 0.34 11.1 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Prothymosin PF03247.14 KEZ44958.1 - 0.22 12.0 26.5 0.37 11.3 26.5 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family RR_TM4-6 PF06459.12 KEZ44958.1 - 0.31 10.8 9.6 0.48 10.2 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 KEZ44958.1 - 0.37 9.8 1.6 0.5 9.3 1.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TLP-20 PF06088.11 KEZ44958.1 - 0.44 10.4 5.0 0.84 9.5 5.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPSF100_C PF13299.6 KEZ44958.1 - 0.45 10.7 3.5 0.88 9.7 3.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_3_Rpc31 PF11705.8 KEZ44958.1 - 0.48 10.6 14.7 0.79 9.9 14.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 KEZ44958.1 - 0.84 8.3 2.3 1.1 8.0 2.3 1.1 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 KEZ44958.1 - 0.86 8.9 14.6 1.4 8.3 14.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 KEZ44958.1 - 1.1 8.2 19.9 1.9 7.4 19.9 1.3 1 0 0 1 1 1 0 Paf1 PI3K_1B_p101 PF10486.9 KEZ44958.1 - 1.1 7.0 5.0 1.4 6.6 5.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RPN2_C PF18004.1 KEZ44958.1 - 1.3 8.9 9.7 2.4 8.0 9.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SURF2 PF05477.11 KEZ44958.1 - 2 8.1 9.1 3.2 7.4 9.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) TRAP_alpha PF03896.16 KEZ44958.1 - 2.4 7.3 8.0 3.5 6.7 8.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Radial_spoke PF04712.12 KEZ44958.1 - 2.4 7.0 15.0 3.5 6.5 15.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4637 PF15470.6 KEZ44958.1 - 3.1 7.5 16.6 5.3 6.7 16.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 KEZ44958.1 - 3.4 5.7 20.9 4.8 5.2 20.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 KEZ44958.1 - 3.4 6.7 12.8 5.9 5.9 12.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF913 PF06025.12 KEZ44958.1 - 3.8 6.4 4.9 5.8 5.8 4.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.6 KEZ44958.1 - 4 7.9 9.8 7.9 6.9 9.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 KEZ44960.1 - 1.5e-15 57.3 0.0 2.8e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ44960.1 - 1.3e-13 50.9 0.0 4e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Methyltransf_23 PF13489.6 KEZ44961.1 - 3.1e-23 82.4 0.0 5.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44961.1 - 6.9e-15 55.5 0.0 2e-14 54.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44961.1 - 2.9e-11 43.9 0.0 8.8e-11 42.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44961.1 - 1.7e-09 38.3 0.0 6.7e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44961.1 - 2.2e-09 37.3 0.0 2.8e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44961.1 - 6.3e-08 32.2 0.0 6e-06 25.8 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ44961.1 - 2.9e-05 24.2 0.0 0.00025 21.2 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ44961.1 - 0.00021 20.9 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ44961.1 - 0.00036 20.0 0.0 0.001 18.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 KEZ44961.1 - 0.00073 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 KEZ44961.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_PK PF05891.12 KEZ44961.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 KEZ44961.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KEZ44961.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PALP PF00291.25 KEZ44962.1 - 2.7e-60 204.3 0.4 4.3e-60 203.6 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 KEZ44962.1 - 5.8e-32 111.1 1.0 1e-31 110.3 0.3 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ44962.1 - 1.1e-16 60.7 0.0 2.3e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEZ44962.1 - 9.7e-07 28.7 0.4 2e-06 27.7 0.4 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 KEZ44962.1 - 0.16 11.0 1.2 5.4 5.9 0.1 2.6 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase ABC_membrane PF00664.23 KEZ44964.1 - 4.8e-86 288.8 32.1 1.1e-47 163.0 8.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ44964.1 - 6.8e-63 211.2 0.0 1.2e-30 106.9 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ44964.1 - 4.7e-17 62.2 0.0 1.7e-08 34.2 0.0 3.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ44964.1 - 4.5e-09 35.9 0.1 0.0002 21.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ44964.1 - 1.1e-08 35.5 0.4 0.02 15.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KEZ44964.1 - 2e-07 31.5 2.7 0.018 15.4 0.2 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KEZ44964.1 - 5.7e-07 29.6 0.1 0.061 13.1 0.0 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KEZ44964.1 - 6.4e-07 29.4 0.0 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KEZ44964.1 - 1.2e-06 28.5 0.1 0.014 15.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 KEZ44964.1 - 1.3e-06 28.5 0.0 0.039 13.9 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_23 PF13476.6 KEZ44964.1 - 2.6e-06 28.1 0.1 0.11 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KEZ44964.1 - 5.2e-06 26.9 0.9 2.2 8.7 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 KEZ44964.1 - 6.4e-05 21.9 0.7 0.043 12.6 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_28 PF13521.6 KEZ44964.1 - 9.9e-05 22.6 0.1 0.42 10.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KEZ44964.1 - 0.00018 21.3 4.7 0.88 9.3 0.0 4.3 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 KEZ44964.1 - 0.00027 21.5 0.0 0.78 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KEZ44964.1 - 0.00096 19.2 0.1 4.1 7.4 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KEZ44964.1 - 0.0017 17.9 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SRP54 PF00448.22 KEZ44964.1 - 0.0018 18.0 0.0 1.4 8.5 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KEZ44964.1 - 0.0019 18.0 0.3 1.5 8.5 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF3987 PF13148.6 KEZ44964.1 - 0.0019 17.3 0.0 0.007 15.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) SbcCD_C PF13558.6 KEZ44964.1 - 0.0022 18.2 8.4 0.59 10.4 0.2 4.7 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KEZ44964.1 - 0.0028 17.8 0.0 4.1 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 KEZ44964.1 - 0.0056 16.5 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 KEZ44964.1 - 0.0063 16.3 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEZ44964.1 - 0.0074 15.9 0.7 2 7.9 0.0 3.3 4 0 0 4 4 3 1 AAA domain ATP-synt_ab PF00006.25 KEZ44964.1 - 0.0079 15.9 2.6 0.8 9.3 0.0 3.5 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain TniB PF05621.11 KEZ44964.1 - 0.02 14.3 0.0 16 4.9 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein RNA_helicase PF00910.22 KEZ44964.1 - 0.028 14.8 0.0 12 6.4 0.0 3.1 3 0 0 3 3 2 0 RNA helicase ABC_membrane_3 PF13748.6 KEZ44964.1 - 0.032 13.4 1.4 0.094 11.9 0.1 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region NTPase_1 PF03266.15 KEZ44964.1 - 0.042 13.8 0.7 59 3.5 0.1 3.8 4 0 0 4 4 4 0 NTPase PRK PF00485.18 KEZ44964.1 - 0.045 13.5 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 KEZ44964.1 - 0.11 12.4 0.0 18 5.2 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase MoeA_C PF03454.15 KEZ44964.1 - 0.11 12.6 0.0 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) AAA_17 PF13207.6 KEZ44964.1 - 0.11 12.9 0.1 16 5.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain SRPRB PF09439.10 KEZ44964.1 - 0.12 11.8 0.0 44 3.5 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KEZ44964.1 - 0.16 11.1 0.1 6.1 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.7 KEZ44964.1 - 0.52 9.2 2.1 1.2 7.9 0.0 2.5 4 0 0 4 4 4 0 AAA-like domain NACHT PF05729.12 KEZ44965.1 - 2.4e-07 30.8 0.0 1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ44965.1 - 8.1e-05 23.1 0.6 0.00059 20.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEZ44965.1 - 0.0034 17.6 0.0 0.013 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ44965.1 - 0.014 14.6 0.0 0.045 12.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KEZ44965.1 - 0.026 14.9 0.1 0.17 12.3 0.0 2.4 3 0 0 3 3 3 0 RNA helicase TFIIA PF03153.13 KEZ44965.1 - 1.5 8.7 12.6 3 7.7 12.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF2_N PF00176.23 KEZ44966.1 - 2.3e-63 214.1 0.0 3.3e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 KEZ44966.1 - 1.7e-06 28.1 0.0 3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ44966.1 - 9.6e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AMP-binding PF00501.28 KEZ44967.1 - 1e-90 304.4 0.0 1.2e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ44967.1 - 1.2e-18 67.9 0.0 3.2e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KEZ44968.1 - 7.1e-27 94.3 60.4 7.1e-27 94.3 60.4 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.6 KEZ44968.1 - 2.6 8.3 5.1 2.7 8.2 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4470 PF14737.6 KEZ44969.1 - 0.00053 20.1 0.1 0.97 9.7 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4470) Wzy_C PF04932.15 KEZ44970.1 - 0.19 11.3 11.1 0.54 9.9 5.3 2.3 2 0 0 2 2 2 0 O-Antigen ligase Methyltransf_23 PF13489.6 KEZ44971.1 - 1.9e-26 92.9 0.0 3.3e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ44971.1 - 1.4e-14 54.6 0.0 3.7e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ44971.1 - 1.9e-12 47.7 0.0 3.9e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ44971.1 - 2.6e-10 40.9 0.0 1.6e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ44971.1 - 8.1e-09 35.4 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ44971.1 - 2.6e-07 30.2 0.0 3.3e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ44971.1 - 0.0014 18.2 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KEZ44971.1 - 0.0031 17.3 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KEZ44971.1 - 0.0038 16.7 0.0 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KEZ44971.1 - 0.0053 16.2 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KEZ44971.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF938 PF06080.12 KEZ44971.1 - 0.033 14.0 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 KEZ44971.1 - 0.042 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 KEZ44971.1 - 0.08 12.2 0.0 0.4 9.9 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KEZ44971.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 KEZ44971.1 - 0.18 11.6 0.0 43 3.8 0.0 3.3 4 0 0 4 4 4 0 Hypothetical methyltransferase DUF3425 PF11905.8 KEZ44972.1 - 5.4e-19 68.4 0.0 9.3e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PHO4 PF01384.20 KEZ44973.1 - 1.3e-113 379.5 4.4 1.5e-113 379.3 4.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF2052 PF09747.9 KEZ44973.1 - 0.00037 20.7 0.4 0.00052 20.2 0.4 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) PBP1_TM PF14812.6 KEZ44973.1 - 0.0089 16.4 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Radial_spoke PF04712.12 KEZ44973.1 - 0.35 9.7 4.2 0.49 9.3 4.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 KEZ44973.1 - 0.63 10.5 9.2 1.2 9.5 9.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 KEZ44973.1 - 1.2 8.7 5.1 3 7.5 5.1 1.6 1 0 0 1 1 1 0 FAM176 family 3Beta_HSD PF01073.19 KEZ44974.1 - 8.1e-19 67.7 0.0 1.8e-18 66.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KEZ44974.1 - 8.2e-10 38.3 0.1 2.3e-07 30.3 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein Epimerase PF01370.21 KEZ44974.1 - 1.1e-08 34.9 0.0 2.4e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KEZ44974.1 - 1.2e-05 25.3 0.0 2.5e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KEZ44974.1 - 1.8e-05 24.8 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ44974.1 - 0.0019 17.4 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KEZ44974.1 - 0.0089 15.2 0.0 0.023 13.8 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KEZ44974.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 KEZ44974.1 - 0.15 12.6 0.0 0.54 10.9 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 KEZ44975.1 - 2e-11 43.9 0.1 5.4e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KEZ44975.1 - 1.4e-08 33.6 0.0 4.1e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEZ44975.1 - 2e-07 30.5 0.0 0.012 14.7 0.0 3.8 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ44975.1 - 3.4e-06 26.5 0.0 3.4e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ44975.1 - 7.6e-06 25.4 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ44975.1 - 1.5e-05 25.1 0.2 0.00044 20.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KEZ44975.1 - 0.0011 18.7 0.0 0.91 9.0 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ44975.1 - 0.0018 17.6 0.0 0.072 12.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KEZ44975.1 - 0.064 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_4 PF01565.23 KEZ44976.1 - 3.5e-24 85.1 0.0 5.5e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ44976.1 - 6.4e-13 48.9 0.0 9.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Defensin_2 PF01097.18 KEZ44977.1 - 2.4e-05 24.2 9.3 3.7e-05 23.6 9.3 1.3 1 0 0 1 1 1 1 Arthropod defensin BTB PF00651.31 KEZ44978.1 - 8e-05 22.8 0.1 0.00061 20.0 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.16 KEZ44979.1 - 1.8e-34 119.2 23.4 8.7e-34 117.0 25.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KEZ44979.1 - 0.87 7.8 8.0 2.6 6.2 0.2 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PRP1_N PF06424.12 KEZ44980.1 - 0.038 14.4 1.5 0.057 13.8 1.5 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3782 PF12644.7 KEZ44980.1 - 0.048 13.8 1.2 0.048 13.8 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) Ras PF00071.22 KEZ44980.1 - 0.054 13.1 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Ras family Ribosomal_L21p PF00829.21 KEZ44980.1 - 0.28 11.5 3.2 0.53 10.6 2.8 1.6 1 1 0 1 1 1 0 Ribosomal prokaryotic L21 protein AAA_28 PF13521.6 KEZ44980.1 - 0.38 11.0 3.2 9.6 6.4 1.0 2.2 1 1 1 2 2 2 0 AAA domain ATP-synt_E PF05680.12 KEZ44980.1 - 6.3 7.2 8.1 0.84 10.0 2.6 2.0 2 0 0 2 2 2 0 ATP synthase E chain FAD_binding_3 PF01494.19 KEZ44981.1 - 8.2e-46 156.8 0.0 7.9e-35 120.7 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain EcoR124_C PF12008.8 KEZ44981.1 - 0.19 11.4 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal GST_N PF02798.20 KEZ44982.1 - 1.5e-15 57.2 0.0 3.8e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEZ44982.1 - 1.8e-11 44.3 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ44982.1 - 7.3e-10 38.9 0.0 9.5e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEZ44982.1 - 1.8e-09 37.7 0.0 4.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ44982.1 - 4e-05 23.6 0.1 6.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF664 PF04978.12 KEZ44982.1 - 0.047 14.1 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF664) C166 PF17615.2 KEZ44983.1 - 4.8e-24 85.3 5.2 6.1e-24 84.9 5.2 1.1 1 0 0 1 1 1 1 Family of unknown function HsbA PF12296.8 KEZ44983.1 - 0.00027 21.3 0.9 0.003 18.0 0.0 2.3 1 1 1 2 2 2 1 Hydrophobic surface binding protein A HET PF06985.11 KEZ44986.1 - 2.4e-26 92.9 1.6 3.6e-26 92.2 0.2 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 KEZ44986.1 - 2e-08 33.5 1.9 2e-08 33.5 1.9 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ44987.1 - 3.9e-56 190.5 29.4 3.9e-56 190.5 29.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ44987.1 - 1e-10 41.1 9.5 1e-10 41.1 9.5 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KEZ44987.1 - 1.9e-08 34.0 5.2 1.9e-08 34.0 5.2 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KEZ44987.1 - 0.00024 19.7 2.1 0.00039 18.9 2.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 KEZ44987.1 - 0.0013 17.1 2.5 0.0013 17.1 2.5 2.4 1 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KEZ44988.1 - 8.3e-49 166.6 0.0 1.1e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FYVE_2 PF02318.16 KEZ44989.1 - 0.16 12.2 1.8 0.8 9.9 1.8 2.1 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 KEZ44989.1 - 0.38 10.9 6.8 0.19 11.9 2.9 2.2 2 0 0 2 2 2 0 B-box zinc finger Amidase PF01425.21 KEZ44990.1 - 3.1e-75 253.9 0.0 1.1e-42 146.6 0.0 2.2 1 1 1 2 2 2 2 Amidase Gag_p15 PF08723.10 KEZ44990.1 - 0.08 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Gag protein p15 Aconitase PF00330.20 KEZ44991.1 - 2.5e-78 264.1 0.0 7.4e-73 246.1 0.0 2.9 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ44991.1 - 4.6e-28 98.2 0.0 7.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MFS_1 PF07690.16 KEZ44992.1 - 5.7e-48 163.6 45.7 9.1e-48 163.0 45.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ44992.1 - 1.9e-18 66.6 5.2 1.9e-18 66.6 5.2 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KEZ44992.1 - 2.5e-05 22.9 27.0 0.00014 20.4 27.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CPSase_L_D2 PF02786.17 KEZ44993.1 - 2.3e-68 229.8 0.1 4.8e-68 228.8 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KEZ44993.1 - 4.5e-59 199.5 0.0 7.2e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KEZ44993.1 - 2.1e-36 124.8 0.1 4.8e-36 123.7 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KEZ44993.1 - 1.6e-29 102.2 0.0 4e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KEZ44993.1 - 3.9e-21 75.8 3.9 2.6e-20 73.1 0.9 2.4 2 0 0 2 2 2 1 HMGL-like Biotin_lipoyl PF00364.22 KEZ44993.1 - 5.3e-16 58.2 0.8 3.3e-15 55.7 0.2 2.6 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KEZ44993.1 - 3.8e-05 23.4 0.0 0.27 11.1 0.0 3.0 1 1 2 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KEZ44993.1 - 7e-05 22.5 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KEZ44993.1 - 0.0014 18.2 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 KEZ44993.1 - 0.0072 17.0 0.0 11 6.8 0.0 3.5 2 1 1 3 3 3 1 HlyD family secretion protein ATP-grasp_3 PF02655.14 KEZ44993.1 - 0.0088 16.1 0.1 0.26 11.3 0.1 2.4 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KEZ44993.1 - 0.057 13.0 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 KEZ44993.1 - 0.097 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp FbpC_C_terminal PF17845.1 KEZ44993.1 - 0.11 12.6 0.0 0.48 10.6 0.0 2.1 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain DUF4231 PF14015.6 KEZ44994.1 - 0.095 13.2 0.2 0.095 13.2 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF3742 PF12553.8 KEZ44994.1 - 0.32 11.1 1.5 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) NAD_binding_6 PF08030.12 KEZ44995.1 - 6.5e-17 62.1 0.0 1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KEZ44995.1 - 3e-13 50.0 3.5 3e-13 50.0 3.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEZ44995.1 - 1.6e-11 44.3 0.0 7e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 KEZ44995.1 - 0.00027 21.5 0.0 0.039 14.6 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain MFS_1 PF07690.16 KEZ44996.1 - 1.5e-29 103.1 43.6 2.6e-27 95.7 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HNH_2 PF13391.6 KEZ44996.1 - 2.4e-14 53.2 0.0 6.7e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease DUF3377 PF11857.8 KEZ44996.1 - 1.3 9.0 2.5 32 4.6 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) WSC PF01822.19 KEZ44997.1 - 1e-36 125.0 46.0 1e-15 57.7 7.9 7.8 7 2 1 8 8 8 4 WSC domain Lipase_GDSL_2 PF13472.6 KEZ44997.1 - 7.6e-07 29.7 0.1 2.4e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SOG2 PF10428.9 KEZ44997.1 - 5.5 6.1 12.7 8.3 5.5 12.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RTA1 PF04479.13 KEZ44999.1 - 1.7e-60 204.2 9.0 2.5e-60 203.6 9.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3267 PF11667.8 KEZ44999.1 - 6.7 7.1 9.9 0.18 12.1 2.2 2.4 2 1 0 2 2 2 0 Putative zincin peptidase hNIFK_binding PF12196.8 KEZ45000.1 - 0.071 12.6 0.2 2.9 7.4 0.0 3.1 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK DUF998 PF06197.13 KEZ45001.1 - 0.071 12.7 0.3 0.094 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Bac_luciferase PF00296.20 KEZ45002.1 - 2.5e-58 198.0 1.0 3.5e-58 197.5 1.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 KEZ45003.1 - 2.7e-10 39.7 34.8 3.8e-10 39.2 34.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEZ45003.1 - 4.6e-05 23.2 5.1 4.6e-05 23.2 5.1 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Ank_2 PF12796.7 KEZ45004.1 - 4.8e-23 81.6 0.6 2.2e-09 37.8 0.0 4.6 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45004.1 - 8.7e-17 61.3 3.4 0.00049 20.6 0.1 5.7 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KEZ45004.1 - 2e-15 56.5 1.7 0.0026 18.1 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 KEZ45004.1 - 8.8e-15 53.3 4.2 0.0009 19.5 0.0 7.3 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 KEZ45004.1 - 6e-14 51.9 4.5 0.016 15.5 0.1 6.2 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Cation_ATPase_C PF00689.21 KEZ45004.1 - 0.1 12.3 0.5 14 5.3 0.1 2.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus TctB PF07331.11 KEZ45004.1 - 9.4 6.5 7.5 4.1 7.7 2.9 2.6 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family GRDP-like PF07173.12 KEZ45005.1 - 1.7e-15 57.9 0.2 9.3e-12 45.8 0.0 2.9 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like Lipase_GDSL_2 PF13472.6 KEZ45007.1 - 1.2e-05 25.9 2.0 3.1e-05 24.4 2.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KEZ45007.1 - 0.015 15.3 0.5 0.071 13.1 0.3 2.3 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase HBS1_N PF08938.10 KEZ45007.1 - 0.15 12.4 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 HBS1 N-terminus AA_permease PF00324.21 KEZ45009.1 - 9.8e-129 430.0 34.0 1.2e-128 429.7 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ45009.1 - 3.3e-46 158.0 36.5 4.4e-46 157.6 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease OmdA PF13376.6 KEZ45011.1 - 2e-18 66.1 0.5 3.6e-18 65.3 0.5 1.4 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated TPR_12 PF13424.6 KEZ45012.1 - 9.9e-82 269.3 44.1 1.2e-17 64.0 1.6 6.0 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ45012.1 - 2.2e-68 224.5 23.6 3.4e-14 52.2 0.5 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ45012.1 - 2.3e-28 96.1 25.3 3.1e-06 26.8 0.2 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ45012.1 - 4.1e-24 82.7 17.9 0.001 19.0 0.2 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ45012.1 - 2.6e-22 77.6 22.2 0.00037 20.2 0.4 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat Patatin PF01734.22 KEZ45012.1 - 4e-22 79.4 1.2 3e-21 76.6 0.3 2.8 2 1 0 2 2 1 1 Patatin-like phospholipase TPR_16 PF13432.6 KEZ45012.1 - 1.4e-17 64.0 7.4 2.3e-06 28.1 0.8 6.4 6 2 1 7 7 5 4 Tetratricopeptide repeat TPR_3 PF07720.12 KEZ45012.1 - 9.7e-16 57.4 9.6 0.05 13.6 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ45012.1 - 1e-15 58.0 17.9 1.7e-08 34.3 4.4 2.9 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 KEZ45012.1 - 1.4e-13 50.1 0.1 1 10.2 0.0 7.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ45012.1 - 2.3e-13 49.7 15.1 0.4 11.6 0.0 8.1 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ45012.1 - 7.2e-13 48.8 25.8 2.3e-05 24.8 2.3 6.3 5 2 2 7 7 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ45012.1 - 8.1e-12 44.8 0.0 1.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 KEZ45012.1 - 1.7e-09 37.2 18.5 1 9.7 0.1 7.0 7 0 0 7 7 6 4 Tetratricopeptide repeat PPR PF01535.20 KEZ45012.1 - 4.4e-08 32.9 0.1 1.4 9.3 0.0 6.5 6 0 0 6 6 6 1 PPR repeat TPR_17 PF13431.6 KEZ45012.1 - 5.6e-06 26.4 16.7 4.2 8.0 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 KEZ45012.1 - 1.2e-05 25.2 11.6 4.1 7.5 0.0 6.8 7 0 0 7 7 6 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 KEZ45012.1 - 0.00011 22.6 0.1 0.00039 20.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain PPR_2 PF13041.6 KEZ45012.1 - 0.00036 20.7 3.9 19 5.5 0.0 5.4 5 0 0 5 5 5 0 PPR repeat family ANAPC3 PF12895.7 KEZ45012.1 - 0.00041 20.5 13.8 1.8 8.9 0.4 4.9 1 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KEZ45012.1 - 0.00051 20.0 11.2 0.055 13.6 0.1 5.7 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat NACHT PF05729.12 KEZ45012.1 - 0.0014 18.6 0.0 0.0035 17.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PPR_1 PF12854.7 KEZ45012.1 - 0.0077 15.9 0.0 4.7 7.0 0.0 4.8 6 0 0 6 6 4 1 PPR repeat Coatomer_E PF04733.14 KEZ45012.1 - 0.019 14.4 4.0 1.6 8.1 0.1 4.0 1 1 3 4 4 4 0 Coatomer epsilon subunit UBM PF14377.6 KEZ45012.1 - 0.027 13.9 0.4 0.44 10.1 0.2 3.1 3 0 0 3 3 3 0 Ubiquitin binding region AAA_22 PF13401.6 KEZ45012.1 - 0.03 14.6 0.0 0.12 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain SHNi-TPR PF10516.9 KEZ45012.1 - 0.03 13.8 6.1 0.38 10.3 0.0 4.3 5 0 0 5 5 5 0 SHNi-TPR Cas_Cmr5 PF09701.10 KEZ45012.1 - 0.042 14.2 0.1 0.66 10.3 0.0 3.0 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) SPO22 PF08631.10 KEZ45012.1 - 0.067 12.7 6.2 0.58 9.6 1.5 3.6 1 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like RPN6_N PF18055.1 KEZ45012.1 - 0.38 11.1 7.1 22 5.4 0.1 4.6 2 1 4 6 6 6 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_6 PF13174.6 KEZ45012.1 - 0.45 11.3 14.1 2.3e+02 2.7 0.1 7.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KEZ45012.1 - 0.47 10.4 6.4 75 3.3 0.2 5.3 5 1 0 5 5 5 0 Mad3/BUB1 homology region 1 Lge1 PF11488.8 KEZ45012.1 - 0.77 10.0 3.1 1.1e+02 3.1 0.0 4.6 5 0 0 5 5 4 0 Transcriptional regulatory protein LGE1 kleA_kleC PF17383.2 KEZ45012.1 - 1.9 8.8 10.3 31 5.0 0.3 5.5 4 2 1 6 6 6 0 Uncharacterized KorC regulated protein A TPR_11 PF13414.6 KEZ45012.1 - 8.9 6.1 21.7 0.25 11.1 0.4 6.1 7 0 0 7 7 5 0 TPR repeat Sugar_tr PF00083.24 KEZ45013.1 - 1.1e-17 64.1 6.5 2.5e-11 43.1 0.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45013.1 - 0.0044 16.0 4.9 0.0068 15.4 4.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2929 PF11151.8 KEZ45013.1 - 0.07 13.4 0.3 0.21 11.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) adh_short PF00106.25 KEZ45014.1 - 7e-24 84.4 0.1 8.2e-24 84.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ45014.1 - 3.2e-15 56.3 0.0 4e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ45014.1 - 1e-05 25.5 0.2 1.3e-05 25.1 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF3701 PF12482.8 KEZ45014.1 - 0.031 14.3 0.0 0.065 13.3 0.0 1.5 1 1 0 1 1 1 0 Phage integrase protein Fungal_trans PF04082.18 KEZ45015.1 - 4.4e-08 32.5 0.0 8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ45016.1 - 8.8e-34 117.0 28.3 8.8e-34 117.0 28.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SLAC1 PF03595.17 KEZ45017.1 - 2.2e-87 293.4 45.7 2.7e-87 293.1 45.7 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Acetyltransf_3 PF13302.7 KEZ45017.1 - 2.5e-08 34.7 0.0 4.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ilar_coat PF01787.16 KEZ45017.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein Sec62 PF03839.16 KEZ45017.1 - 3 7.3 4.8 5.6 6.4 4.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Glyco_hydro_61 PF03443.14 KEZ45018.1 - 1.1e-40 139.8 0.3 8.6e-39 133.6 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Ribonuclease_T2 PF00445.18 KEZ45020.1 - 6.6e-43 147.1 4.8 1.1e-42 146.4 4.8 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Ank_2 PF12796.7 KEZ45021.1 - 1.2e-28 99.5 0.0 2.5e-13 50.4 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45021.1 - 1.8e-27 95.3 0.6 3.2e-09 37.1 0.0 6.4 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ45021.1 - 2.3e-27 94.7 0.9 4.9e-08 33.1 0.0 6.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45021.1 - 1.7e-21 74.0 0.0 0.0084 16.5 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 KEZ45021.1 - 1.1e-17 63.6 0.0 0.0029 18.0 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Amidase PF01425.21 KEZ45023.1 - 1.3e-114 383.7 0.0 1.7e-114 383.3 0.0 1.1 1 0 0 1 1 1 1 Amidase APH PF01636.23 KEZ45024.1 - 9.4e-14 51.9 0.1 2.8e-13 50.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ45024.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_N PF00732.19 KEZ45025.1 - 3.7e-44 151.3 0.0 5.4e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ45025.1 - 1.5e-28 100.1 0.0 2.8e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ45025.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain BBE PF08031.12 KEZ45026.1 - 7.8e-12 45.1 0.0 2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 KEZ45026.1 - 6.3e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain AnkUBD PF18418.1 KEZ45026.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain FAR1 PF03101.15 KEZ45027.1 - 0.00022 21.8 0.2 0.00059 20.5 0.2 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain CDC45 PF02724.14 KEZ45027.1 - 0.32 9.3 3.1 0.5 8.6 3.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.24 KEZ45028.1 - 5.7e-107 358.4 21.0 4.8e-106 355.3 21.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45028.1 - 1.3e-18 67.0 31.9 3.6e-16 59.1 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5316 PF17247.2 KEZ45028.1 - 7 6.7 8.4 0.8 9.8 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5316) Glyco_hydro_3 PF00933.21 KEZ45029.1 - 4.2e-52 177.5 0.0 5.8e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KEZ45029.1 - 4.5e-36 124.7 0.0 7.6e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KEZ45029.1 - 5.5e-15 55.2 0.1 1e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 KEZ45030.1 - 5.4e-30 104.5 32.2 8.3e-30 103.9 32.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.8 KEZ45030.1 - 0.056 12.9 0.1 0.056 12.9 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) MRP-S26 PF14943.6 KEZ45030.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Fungal_trans PF04082.18 KEZ45031.1 - 4.3e-18 65.3 0.0 4e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45031.1 - 4e-08 33.2 9.3 8.7e-08 32.2 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KEZ45032.1 - 1e-57 196.0 0.0 1.3e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.6 KEZ45033.1 - 7.2e-09 35.9 0.6 1.1e-08 35.3 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 KEZ45033.1 - 0.022 15.0 0.5 0.03 14.6 0.5 1.2 1 0 0 1 1 1 0 SnoaL-like domain HIPIP PF01355.17 KEZ45033.1 - 0.041 14.2 0.2 0.071 13.5 0.2 1.4 1 0 0 1 1 1 0 High potential iron-sulfur protein p450 PF00067.22 KEZ45034.1 - 3.4e-53 181.0 0.0 4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 STb_secrete PF09075.10 KEZ45034.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory AMP-binding PF00501.28 KEZ45035.1 - 7.7e-15 54.4 0.0 4.1e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme oligo_HPY PF08352.12 KEZ45035.1 - 0.2 12.2 0.0 0.39 11.3 0.0 1.4 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region Form_Nir_trans PF01226.17 KEZ45036.1 - 1.2e-72 244.1 18.3 1.3e-72 243.9 18.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Sdh_cyt PF01127.22 KEZ45036.1 - 0.0055 16.7 3.4 0.017 15.2 3.4 1.9 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonuc_L-PSP PF01042.21 KEZ45038.1 - 4.9e-05 23.3 0.0 7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_3_C PF01915.22 KEZ45039.1 - 2.5e-56 190.9 0.0 5.4e-56 189.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ45039.1 - 1.7e-46 159.1 0.0 2.6e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ45039.1 - 4.5e-17 61.9 0.0 1e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KEZ45039.1 - 1.2e-06 28.4 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 KEZ45039.1 - 0.024 15.0 0.0 0.077 13.4 0.0 1.9 1 0 0 1 1 1 0 GLEYA domain Sugar_tr PF00083.24 KEZ45040.1 - 1.5e-39 136.1 16.5 7.5e-30 104.2 9.9 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45040.1 - 1.3e-11 44.0 16.2 1.2e-08 34.4 7.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ferlin_C PF16165.5 KEZ45040.1 - 0.18 11.8 1.1 0.32 10.9 1.1 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Zn_clus PF00172.18 KEZ45041.1 - 1.8e-07 31.1 5.7 3.3e-07 30.3 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEZ45042.1 - 7e-55 186.7 26.8 7.3e-25 87.7 10.7 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45042.1 - 1.1e-17 64.0 36.0 1.8e-11 43.5 14.1 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Brr6_like_C_C PF10104.9 KEZ45042.1 - 0.5 10.1 7.0 0.09 12.6 2.4 2.1 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain MFS_1 PF07690.16 KEZ45043.1 - 8.9e-34 116.9 14.9 8.9e-34 116.9 14.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily CAP59_mtransfer PF11735.8 KEZ45044.1 - 2.4e-68 230.4 0.0 3.1e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MFS_1 PF07690.16 KEZ45045.1 - 5.6e-32 111.0 19.3 5.6e-32 111.0 19.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 KEZ45046.1 - 5.9e-58 196.7 0.0 1e-45 156.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF655 PF04919.12 KEZ45046.1 - 0.079 12.9 0.1 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF655) Glyoxalase PF00903.25 KEZ45047.1 - 5.9e-11 42.7 0.0 1.4e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ45047.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CHORD PF04968.12 KEZ45049.1 - 0.025 15.3 1.9 0.11 13.3 0.1 2.4 2 0 0 2 2 2 0 CHORD Ank_4 PF13637.6 KEZ45050.1 - 2.2e-09 37.7 0.1 9.6e-09 35.6 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KEZ45050.1 - 9.6e-09 35.3 0.7 5.7e-05 23.4 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KEZ45050.1 - 1.7e-07 31.7 0.1 4.3e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ45050.1 - 1.7e-06 28.2 0.4 3.7e-05 23.9 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45050.1 - 2e-06 27.7 1.1 0.00022 21.4 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat PLDc_2 PF13091.6 KEZ45050.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain SSF PF00474.17 KEZ45051.1 - 3.5e-24 85.4 24.9 3.5e-24 85.4 24.9 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family NmrA PF05368.13 KEZ45052.1 - 3.3e-21 75.9 0.0 4.7e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ45052.1 - 4.9e-15 55.9 0.0 1.3e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ45052.1 - 0.0069 15.9 0.1 0.027 13.9 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ45052.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KEZ45052.1 - 0.068 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 KR domain Beta_elim_lyase PF01212.21 KEZ45052.1 - 0.16 11.2 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase SET PF00856.28 KEZ45053.1 - 0.0082 16.5 0.0 0.0091 16.4 0.0 1.2 1 0 0 1 1 1 1 SET domain Transferase PF02458.15 KEZ45054.1 - 1.1e-05 24.3 0.0 2.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Transferase family Methyltransf_23 PF13489.6 KEZ45055.1 - 7e-20 71.5 0.0 1.1e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45055.1 - 1.1e-13 51.7 0.0 2.5e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45055.1 - 1.1e-11 45.4 0.0 2.8e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45055.1 - 6.7e-11 42.7 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45055.1 - 1.3e-09 38.1 0.0 3.2e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45055.1 - 3e-07 30.0 0.0 2.8e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KEZ45055.1 - 2.4e-05 23.9 0.1 0.0005 19.6 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.14 KEZ45055.1 - 0.00072 19.1 0.0 0.0049 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 KEZ45055.1 - 0.071 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 KEZ45055.1 - 0.085 12.6 0.0 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 KEZ45055.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KEZ45055.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MFS_1 PF07690.16 KEZ45056.1 - 1e-21 77.3 54.6 3.2e-16 59.2 28.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ45056.1 - 5.7e-11 41.5 20.6 6.9e-11 41.3 19.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Chromo PF00385.24 KEZ45060.1 - 2.2e-05 24.3 4.5 0.033 14.1 0.4 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_31 PF01055.26 KEZ45062.1 - 7.8e-49 167.0 3.4 7.7e-37 127.5 0.6 3.2 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 HET PF06985.11 KEZ45062.1 - 8.1e-32 110.6 0.4 8.1e-32 110.6 0.4 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Gal_mutarotas_2 PF13802.6 KEZ45062.1 - 1.8e-12 47.4 0.0 8.3e-12 45.3 0.0 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Tyrosinase PF00264.20 KEZ45063.1 - 1.3e-38 133.5 0.0 2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 KEZ45064.1 - 5.7e-23 81.4 55.6 3e-20 72.5 45.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.19 KEZ45065.1 - 4.2e-24 84.9 0.0 7.5e-15 54.3 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ45065.1 - 6.9e-09 35.4 0.0 7.2e-07 28.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ45065.1 - 0.00024 20.4 0.0 0.0057 15.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2OG-FeII_Oxy PF03171.20 KEZ45067.1 - 8.1e-17 61.6 0.1 1.3e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KEZ45067.1 - 3.9e-09 37.3 0.0 6.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Polysacc_deac_2 PF04748.13 KEZ45067.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Amidohydro_3 PF07969.11 KEZ45068.1 - 4.1e-12 46.3 2.4 5.6e-10 39.3 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KEZ45068.1 - 5.9e-11 42.3 0.0 2.5e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family PHD_2 PF13831.6 KEZ45068.1 - 0.22 11.1 0.2 0.48 10.0 0.2 1.5 1 0 0 1 1 1 0 PHD-finger GMC_oxred_N PF00732.19 KEZ45069.1 - 8.5e-78 261.7 0.0 1.2e-77 261.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ45069.1 - 7.7e-34 117.3 0.0 2.6e-33 115.6 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEZ45069.1 - 0.00011 21.4 0.1 0.00016 20.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEZ45069.1 - 0.00027 20.1 0.1 0.45 9.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KEZ45069.1 - 0.002 17.8 1.7 0.012 15.2 1.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ45069.1 - 0.0052 16.1 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ45069.1 - 0.0089 15.3 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family DUF2458 PF10454.9 KEZ45070.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF1706 PF08020.11 KEZ45070.1 - 0.18 11.7 1.5 0.2 11.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) OTT_1508_deam PF14441.6 KEZ45071.1 - 6.6e-20 70.9 1.4 1.6e-19 69.7 1.4 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Fungal_trans PF04082.18 KEZ45072.1 - 2.5e-16 59.5 0.2 3.6e-16 59.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEZ45072.1 - 0.11 13.0 0.1 0.32 11.6 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type adh_short_C2 PF13561.6 KEZ45073.1 - 7.9e-61 205.6 1.0 1e-60 205.2 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ45073.1 - 3.2e-43 147.5 0.6 3.9e-43 147.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ45073.1 - 8.9e-09 35.5 0.4 1.7e-08 34.6 0.4 1.5 1 0 0 1 1 1 1 KR domain ThiF PF00899.21 KEZ45073.1 - 0.00064 19.1 3.0 0.1 11.9 0.6 2.4 1 1 1 2 2 2 2 ThiF family Methyltransf_25 PF13649.6 KEZ45073.1 - 0.024 15.3 0.1 0.69 10.6 0.1 2.5 1 1 1 2 2 2 0 Methyltransferase domain DUF5448 PF17526.2 KEZ45073.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Amidase PF01425.21 KEZ45074.1 - 5.1e-88 296.0 0.0 6.6e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 Amidase ADH_N PF08240.12 KEZ45075.1 - 5.2e-23 81.0 0.9 1.1e-22 80.0 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ45075.1 - 2.7e-15 56.5 0.0 5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KEZ45075.1 - 0.0039 16.6 0.1 0.0063 15.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KEZ45075.1 - 0.018 15.5 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain ATPgrasp_N PF18130.1 KEZ45075.1 - 0.14 12.7 0.4 0.32 11.6 0.2 1.7 2 0 0 2 2 2 0 ATP-grasp N-terminal domain Polysacc_deac_1 PF01522.21 KEZ45076.1 - 3.8e-19 68.8 0.0 9e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KEZ45076.1 - 7.8e-06 25.7 0.1 1.5e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KEZ45076.1 - 0.078 11.3 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Aa_trans PF01490.18 KEZ45077.1 - 3.7e-28 98.4 33.3 4.6e-28 98.1 33.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF872 PF05915.12 KEZ45077.1 - 0.039 14.1 1.6 0.67 10.1 0.4 3.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Abhydrolase_6 PF12697.7 KEZ45078.1 - 3.7e-11 44.1 1.9 4.5e-11 43.8 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DegV PF02645.16 KEZ45078.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 PGAP1 PF07819.13 KEZ45078.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein adh_short PF00106.25 KEZ45079.1 - 1.4e-37 129.0 0.0 1.9e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ45079.1 - 1.2e-27 97.0 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KEZ45079.1 - 0.00021 21.2 0.0 0.00039 20.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding ACR_tran PF00873.19 KEZ45080.1 - 0.11 10.1 1.1 0.16 9.6 1.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family APH PF01636.23 KEZ45081.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.29 KEZ45082.1 - 8e-08 32.8 0.0 5.1e-07 30.2 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KEZ45082.1 - 0.00013 22.1 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ45082.1 - 0.00024 21.6 0.0 0.0014 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ45082.1 - 0.00038 20.9 0.0 0.00091 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEZ45082.1 - 0.0031 17.5 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ45082.1 - 0.0056 17.0 0.0 0.019 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KEZ45082.1 - 0.0081 16.3 0.0 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KEZ45082.1 - 0.01 15.2 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEZ45082.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KEZ45082.1 - 0.012 15.9 0.0 0.1 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KEZ45082.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 KEZ45082.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KEZ45082.1 - 0.041 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ45082.1 - 0.047 13.6 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.13 KEZ45082.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain PhoH PF02562.16 KEZ45082.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 KEZ45082.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 KEZ45082.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sulfatase PF00884.23 KEZ45083.1 - 2.8e-71 240.5 0.0 4.2e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Ank_2 PF12796.7 KEZ45083.1 - 5e-34 116.7 6.5 3.8e-10 40.2 0.1 6.3 4 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45083.1 - 2.4e-30 104.5 8.9 6.8e-06 26.5 0.3 7.7 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ45083.1 - 4.4e-26 90.6 9.6 1e-05 25.7 0.0 7.5 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 KEZ45083.1 - 7.9e-23 79.8 17.4 1.2e-05 25.6 0.0 9.8 10 0 0 10 10 9 5 Ankyrin repeat Ank_3 PF13606.6 KEZ45083.1 - 1.4e-20 71.2 10.2 6.4e-05 23.1 0.0 10.7 11 1 0 11 11 10 3 Ankyrin repeat AAA_16 PF13191.6 KEZ45083.1 - 1.6e-08 35.1 0.0 5.9e-08 33.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEZ45083.1 - 6.7e-07 29.4 0.0 6.9e-06 26.1 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ45083.1 - 2.1e-05 24.8 0.0 0.00013 22.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KEZ45083.1 - 0.0048 16.2 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KEZ45083.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4976 PF16347.5 KEZ45083.1 - 0.016 15.4 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KEZ45083.1 - 0.019 15.7 0.3 0.2 12.4 0.3 2.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.17 KEZ45083.1 - 0.021 13.4 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) NB-ARC PF00931.22 KEZ45083.1 - 0.027 13.6 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 KEZ45083.1 - 0.031 14.7 0.0 1.2 9.5 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KEZ45083.1 - 0.048 14.0 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KEZ45083.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KEZ45083.1 - 0.059 13.9 0.0 0.19 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 KEZ45083.1 - 0.059 13.3 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Phosphodiest PF01663.22 KEZ45083.1 - 0.1 12.2 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase NTPase_1 PF03266.15 KEZ45083.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 KEZ45083.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KEZ45083.1 - 0.15 11.3 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain MMR_HSR1 PF01926.23 KEZ45083.1 - 0.23 11.5 0.7 1.1 9.4 0.0 2.5 3 0 0 3 3 2 0 50S ribosome-binding GTPase Sugar_tr PF00083.24 KEZ45084.1 - 5.7e-81 272.7 12.3 1.1e-80 271.8 12.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45084.1 - 8.5e-17 61.1 15.2 8.5e-17 61.1 15.2 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Hol_Tox PF16935.5 KEZ45084.1 - 0.0082 16.2 1.2 0.028 14.4 0.0 2.6 3 0 0 3 3 3 1 Putative Holin-like Toxin (Hol-Tox) DUF5325 PF17259.2 KEZ45084.1 - 0.043 13.7 1.1 0.043 13.7 1.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5325) TRI12 PF06609.13 KEZ45084.1 - 0.28 9.5 6.3 0.73 8.2 0.3 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Romo1 PF10247.9 KEZ45084.1 - 1.7 9.0 7.4 11 6.5 0.4 3.5 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 WRW PF10206.9 KEZ45087.1 - 0.045 14.1 0.0 0.28 11.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f PTP_tm PF18861.1 KEZ45087.1 - 0.056 13.4 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Herpes_gE PF02480.16 KEZ45087.1 - 0.21 10.3 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GMC_oxred_N PF00732.19 KEZ45088.1 - 4.1e-50 170.8 0.0 5.5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ45088.1 - 6e-32 111.1 0.0 9.9e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KEZ45088.1 - 0.0008 19.1 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ45088.1 - 0.0013 18.9 0.2 0.006 16.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ45088.1 - 0.0013 18.0 0.0 0.039 13.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Hormone_recep PF00104.30 KEZ45088.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor NAD_binding_9 PF13454.6 KEZ45088.1 - 0.021 14.8 0.1 0.1 12.6 0.0 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEZ45088.1 - 0.03 13.6 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ45088.1 - 0.057 12.5 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KEZ45088.1 - 0.1 11.6 0.0 7.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KEZ45088.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Dioxygenase_C PF00775.21 KEZ45089.1 - 4e-08 32.9 0.7 1.6e-07 30.9 0.7 1.9 1 1 0 1 1 1 1 Dioxygenase SpaA PF17802.1 KEZ45089.1 - 0.032 14.6 0.3 0.17 12.3 0.0 2.2 1 1 1 2 2 2 0 Prealbumin-like fold domain MFS_1 PF07690.16 KEZ45090.1 - 2.1e-40 138.7 45.9 2.1e-40 138.7 45.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KEZ45091.1 - 2.5e-08 33.3 0.0 8.9e-08 31.5 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KEZ45092.1 - 3.3e-14 52.6 1.3 5.8e-14 51.8 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spherulin4 PF12138.8 KEZ45093.1 - 7.5e-23 81.4 1.0 1.9e-22 80.1 1.0 1.7 1 1 0 1 1 1 1 Spherulation-specific family 4 MARVEL PF01284.23 KEZ45095.1 - 2.7 8.0 11.2 4.4 7.3 11.2 1.4 1 0 0 1 1 1 0 Membrane-associating domain Fungal_trans PF04082.18 KEZ45096.1 - 3.6e-17 62.3 1.6 6.3e-17 61.5 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45096.1 - 2.4e-09 37.1 11.9 4.7e-09 36.2 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carboxyl_trans PF01039.22 KEZ45097.1 - 1.3e-34 119.7 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_M PF02770.19 KEZ45097.1 - 9.4e-22 77.0 0.1 1.8e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEZ45097.1 - 0.07 13.8 0.0 0.24 12.1 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain CMD PF02627.20 KEZ45098.1 - 0.035 14.2 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DUF3500 PF12006.8 KEZ45099.1 - 2.6e-96 322.6 0.0 3.2e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Fungal_trans PF04082.18 KEZ45100.1 - 3.5e-08 32.8 0.9 0.00034 19.7 0.1 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF4470 PF14737.6 KEZ45101.1 - 2.8e-24 85.2 0.5 1e-23 83.4 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4470) E1-E2_ATPase PF00122.20 KEZ45102.1 - 1.4e-38 132.2 24.5 9.5e-33 113.2 0.1 3.9 3 1 1 4 4 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KEZ45102.1 - 1.4e-20 73.8 4.8 1.4e-20 73.8 4.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KEZ45102.1 - 2.9e-19 70.2 0.0 8.6e-15 55.6 0.0 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ45102.1 - 3e-17 62.5 0.0 7.2e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KEZ45102.1 - 1e-15 57.1 0.2 4.9e-15 55.0 0.2 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ45102.1 - 0.00015 21.6 0.4 0.00031 20.6 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KEZ45102.1 - 0.013 15.4 0.8 0.033 14.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Transgly_assoc PF04226.13 KEZ45102.1 - 0.017 15.4 3.0 0.017 15.4 3.0 2.7 3 0 0 3 3 2 0 Transglycosylase associated protein Spore_IV_A PF09547.10 KEZ45102.1 - 0.02 13.9 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) SLATT_5 PF18160.1 KEZ45102.1 - 0.021 14.1 0.5 0.056 12.8 0.5 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Caveolin PF01146.17 KEZ45102.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.9 3 0 0 3 3 2 0 Caveolin AAA PF00004.29 KEZ45103.1 - 9.7e-19 68.1 0.0 2.5e-18 66.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ45103.1 - 0.00031 21.0 0.0 0.0022 18.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ45103.1 - 0.00056 20.3 0.1 0.0033 17.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEZ45103.1 - 0.00091 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zot PF05707.12 KEZ45103.1 - 0.002 17.8 0.1 0.061 13.0 0.0 2.8 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) RuvB_N PF05496.12 KEZ45103.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KEZ45103.1 - 0.034 13.4 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KEZ45103.1 - 0.036 13.8 0.1 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KEZ45103.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 KEZ45103.1 - 0.068 13.3 0.0 1.4 9.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KEZ45103.1 - 0.081 13.5 0.0 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ45103.1 - 0.19 12.1 0.0 0.56 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Hydin_ADK PF17213.3 KEZ45103.1 - 0.19 12.0 0.0 0.47 10.7 0.0 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain His_Phos_1 PF00300.22 KEZ45106.1 - 7.7e-07 29.0 0.0 8.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AOX PF01786.17 KEZ45107.1 - 8.4e-92 306.6 0.1 1e-91 306.4 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Zn_clus PF00172.18 KEZ45108.1 - 3.5e-08 33.4 8.8 9.3e-08 32.1 8.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEZ45109.1 - 2.3e-88 297.0 23.9 2.6e-88 296.9 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45109.1 - 3.6e-21 75.5 30.9 3.6e-21 75.5 30.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ45109.1 - 0.0059 16.0 2.2 0.0059 16.0 2.2 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TauD PF02668.16 KEZ45110.1 - 6.9e-57 193.3 1.4 8.1e-57 193.0 1.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.6 KEZ45110.1 - 0.0079 16.9 0.0 0.31 11.8 0.0 2.4 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Pkinase PF00069.25 KEZ45113.1 - 5.5e-20 71.8 0.0 9.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45113.1 - 1.4e-11 44.2 0.0 4e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase VCBS PF13517.6 KEZ45113.1 - 1.4e-09 38.4 17.3 3.6e-07 30.7 3.8 3.8 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KEZ45113.1 - 0.00052 20.1 16.8 0.096 12.8 0.1 3.9 4 0 0 4 4 4 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 KEZ45113.1 - 0.16 11.3 2.8 8.5 5.7 0.1 3.1 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region CorA PF01544.18 KEZ45114.1 - 5.2e-05 22.7 2.2 0.0012 18.2 0.1 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EMP70 PF02990.16 KEZ45114.1 - 0.083 11.5 1.4 0.13 10.9 1.4 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Not3 PF04065.15 KEZ45114.1 - 0.1 12.0 1.0 0.29 10.5 0.1 1.9 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Pkinase PF00069.25 KEZ45115.1 - 1.7e-15 57.1 0.0 3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF3632 PF12311.8 KEZ45116.1 - 3.5e-20 73.2 0.5 4.6e-18 66.3 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3632) NACHT PF05729.12 KEZ45119.1 - 0.0011 18.9 0.2 0.0038 17.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain GP52 PF17468.2 KEZ45119.1 - 0.0036 17.4 0.0 0.01 16.0 0.0 1.7 2 0 0 2 2 2 1 Phage gene product 52 AA_permease PF00324.21 KEZ45120.1 - 2.8e-105 352.7 41.2 2.9e-104 349.3 41.2 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ45120.1 - 1e-31 110.3 33.5 1.6e-31 109.6 33.5 1.3 1 1 0 1 1 1 1 Amino acid permease TMEM208_SND2 PF05620.11 KEZ45120.1 - 0.00068 19.4 0.3 1 9.1 0.3 3.0 2 0 0 2 2 2 2 SRP-independent targeting protein 2/TMEM208 PepSY_TM PF03929.16 KEZ45120.1 - 6.7 6.3 7.5 26 4.4 7.3 2.1 1 1 0 1 1 1 0 PepSY-associated TM region Aminotran_1_2 PF00155.21 KEZ45121.1 - 8.4e-40 137.1 0.0 1e-39 136.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.11 KEZ45122.1 - 1.2e-74 251.9 0.0 6e-38 130.9 0.0 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KEZ45122.1 - 9e-06 25.3 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KEZ45122.1 - 0.00023 20.5 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chromo PF00385.24 KEZ45123.1 - 4e-10 39.4 0.2 0.00036 20.4 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4746 PF15928.5 KEZ45123.1 - 0.28 10.6 7.1 0.57 9.6 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GOLD_2 PF13897.6 KEZ45123.1 - 1.2 9.6 7.0 0.55 10.7 4.0 1.8 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.14 KEZ45123.1 - 2.3 6.4 8.1 3.2 5.9 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KEZ45123.1 - 2.3 7.5 14.8 5.1 6.4 14.8 1.6 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEZ45123.1 - 2.4 6.2 15.1 3.5 5.7 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family Thi4 PF01946.17 KEZ45124.1 - 5.4e-114 379.3 0.1 6.4e-114 379.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KEZ45124.1 - 3.9e-06 26.7 5.4 4.6e-05 23.2 3.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ45124.1 - 0.0003 21.0 0.6 0.00077 19.6 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ45124.1 - 0.00035 19.9 0.1 0.00047 19.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ45124.1 - 0.0005 19.3 2.0 0.013 14.6 0.7 2.3 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KEZ45124.1 - 0.0022 17.1 1.5 0.005 15.9 0.8 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KEZ45124.1 - 0.014 15.4 0.1 0.014 15.4 0.1 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KEZ45124.1 - 0.04 13.3 0.6 0.078 12.3 0.6 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ45124.1 - 0.078 11.7 0.7 0.12 11.0 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ45124.1 - 0.09 12.0 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-RVT PF13966.6 KEZ45125.1 - 0.057 14.1 0.8 0.28 11.9 0.1 2.2 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase YpmT PF17431.2 KEZ45125.1 - 3.1 7.9 4.9 1.7 8.7 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized YmpT-like GMC_oxred_N PF00732.19 KEZ45126.1 - 6.4e-55 186.6 0.0 8.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ45126.1 - 2.7e-34 118.8 0.0 4.6e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KEZ45126.1 - 0.00031 19.9 0.4 0.00056 19.1 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ45126.1 - 0.006 16.8 1.0 0.018 15.3 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ45126.1 - 0.015 14.9 0.4 0.015 14.9 0.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ45126.1 - 0.021 14.1 1.0 0.044 13.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.23 KEZ45126.1 - 0.038 13.9 0.1 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif HI0933_like PF03486.14 KEZ45126.1 - 0.093 11.4 0.7 0.37 9.4 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KEZ45126.1 - 0.14 11.4 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KEZ45126.1 - 0.36 10.1 0.9 11 5.1 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ45126.1 - 0.66 9.0 1.8 8.3 5.4 0.4 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NDUF_B7 PF05676.13 KEZ45127.1 - 2.7e-30 103.9 5.9 3.2e-30 103.6 5.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KEZ45127.1 - 0.014 15.4 1.5 0.018 15.0 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GTP_cyclohydro2 PF00925.20 KEZ45129.1 - 4.4e-60 202.0 0.0 6.4e-60 201.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II PTR2 PF00854.21 KEZ45130.1 - 4.2e-75 253.0 3.0 1.1e-74 251.6 0.7 2.5 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 KEZ45130.1 - 2e-09 36.9 14.0 2e-09 36.9 14.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily EI24 PF07264.11 KEZ45130.1 - 0.0047 17.2 8.5 0.014 15.6 0.0 3.2 2 1 1 3 3 3 1 Etoposide-induced protein 2.4 (EI24) GFO_IDH_MocA PF01408.22 KEZ45132.1 - 7.6e-15 55.8 0.0 1.3e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KEZ45132.1 - 0.019 15.6 0.0 0.053 14.2 0.0 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain SGL PF08450.12 KEZ45133.1 - 5e-27 95.0 0.1 1.4e-15 57.6 0.0 2.1 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KEZ45133.1 - 0.00046 20.3 0.0 0.0013 18.9 0.0 1.8 1 1 0 1 1 1 1 Arylesterase Str_synth PF03088.16 KEZ45133.1 - 0.0028 17.7 0.0 0.013 15.6 0.0 2.2 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.21 KEZ45133.1 - 0.14 12.2 3.4 7.9 6.7 0.0 4.1 4 0 0 4 4 4 0 NHL repeat Methyltransf_23 PF13489.6 KEZ45134.1 - 1.9e-11 44.1 0.0 5.2e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45134.1 - 0.0001 22.9 0.0 0.00024 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45134.1 - 0.0015 18.4 0.0 0.0076 16.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45134.1 - 0.0033 18.1 0.0 0.0059 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SCNM1_acidic PF15805.5 KEZ45134.1 - 0.029 14.1 0.1 0.029 14.1 0.1 2.2 3 0 0 3 3 3 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Methyltransf_11 PF08241.12 KEZ45134.1 - 0.029 15.0 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ABC2_membrane PF01061.24 KEZ45135.1 - 9.8e-48 162.3 56.5 1.9e-33 115.7 11.6 4.8 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ45135.1 - 4.7e-26 91.9 0.0 7.7e-14 52.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEZ45135.1 - 1.5e-17 63.3 16.0 1.6e-17 63.2 0.0 3.6 4 0 0 4 4 3 2 CDR ABC transporter AAA_16 PF13191.6 KEZ45135.1 - 3.8e-05 24.1 0.4 0.22 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KEZ45135.1 - 0.00033 20.8 0.1 0.031 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEZ45135.1 - 0.00045 19.9 0.1 0.014 15.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ45135.1 - 0.0012 19.1 0.4 0.24 11.7 0.2 3.5 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KEZ45135.1 - 0.0018 18.2 0.0 0.011 15.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KEZ45135.1 - 0.0042 16.8 0.2 2.3 8.0 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KEZ45135.1 - 0.0049 17.4 0.0 0.15 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEZ45135.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KEZ45135.1 - 0.069 12.4 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 KEZ45135.1 - 0.076 13.1 0.1 13 5.9 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase HEPN_RES_NTD1 PF18870.1 KEZ45135.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 AAA_30 PF13604.6 KEZ45135.1 - 0.17 11.6 0.1 5.4 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KEZ45135.1 - 0.17 11.4 0.8 0.38 10.3 0.3 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEZ45135.1 - 0.21 11.5 1.8 1 9.3 0.2 2.5 3 0 0 3 3 3 0 NACHT domain DUF4227 PF14004.6 KEZ45135.1 - 0.44 10.6 4.4 1.9 8.5 4.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DAHP_synth_2 PF01474.16 KEZ45136.1 - 7.3e-109 364.2 0.0 1e-70 238.5 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family DAHP_synth_1 PF00793.20 KEZ45136.1 - 0.049 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 DAHP synthetase I family AMP-binding PF00501.28 KEZ45137.1 - 2.2e-45 155.0 0.0 7.8e-45 153.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ45137.1 - 3.5e-11 43.9 0.0 8.9e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glutaredoxin2_C PF04399.13 KEZ45137.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DNA_pol_E_B PF04042.16 KEZ45138.1 - 7.5e-56 188.8 0.0 1.2e-55 188.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Methyltransf_16 PF10294.9 KEZ45140.1 - 2.4e-18 66.5 0.0 3.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KEZ45140.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ45140.1 - 9.4e-05 22.3 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KEZ45140.1 - 0.00018 22.1 0.0 0.00034 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEZ45140.1 - 0.00049 19.6 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KEZ45140.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KEZ45140.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KEZ45140.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45140.1 - 0.041 14.6 0.0 0.1 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 KEZ45140.1 - 0.063 13.0 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_3 PF01596.17 KEZ45140.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Ribosomal_S24e PF01282.19 KEZ45141.1 - 3.6e-35 119.8 0.0 6.3e-35 119.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 KEZ45141.1 - 0.03 14.2 3.0 0.099 12.5 3.0 1.8 1 1 0 1 1 1 0 RRXRR protein SH2_2 PF14633.6 KEZ45143.1 - 6.2e-83 277.5 0.0 6.2e-83 277.5 0.0 2.2 2 0 0 2 2 1 1 SH2 domain HTH_44 PF14641.6 KEZ45143.1 - 1.1e-39 135.4 0.8 3.5e-39 133.8 0.8 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KEZ45143.1 - 1.1e-31 109.2 0.0 2.6e-31 108.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 KEZ45143.1 - 7.1e-29 100.5 0.0 3.5e-28 98.3 0.0 2.3 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KEZ45143.1 - 1.1e-19 70.8 30.6 1.1e-19 70.8 30.6 6.7 3 2 5 8 8 4 1 Acidic N-terminal SPT6 S1 PF00575.23 KEZ45143.1 - 2e-06 28.0 0.9 5.5e-06 26.6 0.9 1.8 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 KEZ45143.1 - 2.8e-05 24.9 1.0 2.8e-05 24.9 1.0 4.5 4 1 0 4 4 4 1 HHH domain SH2 PF00017.24 KEZ45143.1 - 0.00044 20.3 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KEZ45143.1 - 0.0027 17.9 0.0 0.0085 16.3 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif B12-binding PF02310.19 KEZ45143.1 - 0.12 12.5 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain MDM1 PF15501.6 KEZ45143.1 - 0.44 9.6 16.7 0.84 8.7 16.7 1.4 1 0 0 1 1 1 0 Nuclear protein MDM1 HAD_2 PF13419.6 KEZ45144.1 - 1.2e-10 41.8 0.0 7.7e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ45144.1 - 1.8e-06 27.9 0.1 4.2e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEZ45144.1 - 9.8e-06 26.0 0.1 0.29 11.4 0.0 2.9 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KEZ45144.1 - 0.013 15.9 0.1 0.4 11.1 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KEZ45144.1 - 0.11 12.1 0.0 0.69 9.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Pkinase PF00069.25 KEZ45145.1 - 6.7e-65 219.1 0.0 1.5e-64 217.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45145.1 - 1.1e-39 136.3 0.0 1.6e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ45145.1 - 0.00016 21.1 0.0 0.00045 19.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like SUIM_assoc PF16619.5 KEZ45145.1 - 0.00018 21.5 4.1 0.00045 20.2 4.1 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Pkinase_fungal PF17667.1 KEZ45145.1 - 0.0002 20.3 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KEZ45145.1 - 0.029 13.3 1.5 0.035 13.1 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Spt20 PF12090.8 KEZ45145.1 - 0.28 10.8 6.4 0.21 11.1 5.0 1.5 2 0 0 2 2 2 0 Spt20 family FUSC_2 PF13515.6 KEZ45146.1 - 1.7e-24 86.3 6.5 1.7e-24 86.3 6.5 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 KEZ45146.1 - 7.4e-06 24.8 21.9 4.9e-05 22.1 6.2 3.2 3 2 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 KEZ45146.1 - 7e-05 22.8 0.1 0.0096 15.8 0.0 3.4 4 0 0 4 4 4 1 Aromatic acid exporter family member 2 ALMT PF11744.8 KEZ45146.1 - 0.052 12.4 10.0 0.41 9.4 2.4 4.2 4 0 0 4 4 4 0 Aluminium activated malate transporter Glyco_hydro_16 PF00722.21 KEZ45147.1 - 0.00023 20.7 3.8 0.00031 20.3 0.0 2.8 3 1 1 4 4 4 1 Glycosyl hydrolases family 16 Formyl_trans_N PF00551.19 KEZ45148.1 - 8.1e-20 71.3 0.0 1.8e-19 70.2 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 KEZ45148.1 - 0.034 14.4 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain CDH-cyt PF16010.5 KEZ45150.1 - 1.1e-21 77.4 0.0 2.3e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KEZ45150.1 - 1.6e-08 34.8 11.5 3.2e-08 33.8 11.5 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KEZ45150.1 - 4.4e-05 23.2 0.9 4.4e-05 23.2 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) L_HMGIC_fpl PF10242.9 KEZ45150.1 - 0.16 12.2 0.7 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein DUF4179 PF13786.6 KEZ45150.1 - 0.45 11.0 0.1 0.45 11.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF4079 PF13301.6 KEZ45150.1 - 0.9 9.7 12.3 17 5.5 12.3 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Mem_trans PF03547.18 KEZ45150.1 - 1.4 7.3 4.5 0.18 10.2 0.2 1.7 2 0 0 2 2 2 0 Membrane transport protein DUF5125 PF17163.4 KEZ45151.1 - 0.043 14.0 0.1 0.076 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5125) Cu-oxidase_3 PF07732.15 KEZ45152.1 - 1.9e-40 137.6 7.1 7.9e-40 135.6 4.4 2.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEZ45152.1 - 3.7e-40 136.8 13.1 3.8e-40 136.8 2.4 3.3 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KEZ45152.1 - 8e-34 117.1 0.1 1.7e-33 116.0 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Pkinase PF00069.25 KEZ45153.1 - 1.7e-23 83.3 0.0 3.7e-10 39.6 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45153.1 - 1.4e-07 31.1 0.0 0.041 13.2 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KEZ45153.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KEZ45153.1 - 0.035 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ45153.1 - 0.12 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CorA PF01544.18 KEZ45154.1 - 4.7e-06 26.1 0.1 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SNF2_N PF00176.23 KEZ45155.1 - 1.1e-12 47.4 0.0 6.4e-12 44.9 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 KEZ45155.1 - 1.2e-10 41.3 0.0 9.4e-08 31.8 0.0 2.5 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.6 KEZ45155.1 - 0.00027 20.9 3.8 0.00027 20.9 3.8 2.9 3 0 0 3 3 3 1 zinc-RING finger domain Helicase_C PF00271.31 KEZ45155.1 - 0.0009 19.6 0.0 0.003 17.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ45155.1 - 0.026 14.5 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 KEZ45155.1 - 0.45 10.6 15.6 0.031 14.3 3.0 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KEZ45155.1 - 0.85 9.5 30.8 0.053 13.4 7.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L44 PF00935.19 KEZ45157.1 - 2.8e-36 123.9 12.1 3.9e-36 123.4 12.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Rho_N PF07498.12 KEZ45158.1 - 0.017 15.0 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain p450 PF00067.22 KEZ45159.1 - 1.7e-48 165.6 0.0 3.6e-36 124.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 KEZ45160.1 - 6.7e-12 45.0 41.7 8.1e-11 41.4 14.9 4.3 3 1 1 4 4 4 3 Major Facilitator Superfamily DUF4637 PF15470.6 KEZ45160.1 - 2 8.1 4.8 4.4 7.0 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Glyoxalase_6 PF18029.1 KEZ45162.1 - 1.3e-05 25.9 0.0 2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KEZ45162.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.25 KEZ45163.1 - 6.8e-08 32.2 0.0 1.7e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.18 KEZ45164.1 - 6.2e-24 84.4 0.0 9.3e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45164.1 - 0.0059 16.7 5.2 0.0099 16.0 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2408 PF10303.9 KEZ45165.1 - 0.027 15.0 0.0 11 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) gag-asp_proteas PF13975.6 KEZ45166.1 - 3.1e-06 27.7 0.0 6.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KEZ45166.1 - 2.7e-05 24.7 0.0 5.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DLIC PF05783.11 KEZ45166.1 - 0.0089 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) MFS_1 PF07690.16 KEZ45167.1 - 2.9e-31 108.7 51.2 7.1e-31 107.4 51.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45167.1 - 3.5e-08 32.7 10.6 3.5e-08 32.7 10.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ45167.1 - 0.0053 15.2 23.4 0.0081 14.6 23.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2 PF00096.26 KEZ45168.1 - 6.1e-06 26.4 13.0 0.01 16.3 2.9 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ45168.1 - 0.0006 20.4 11.0 0.27 12.2 1.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger CTP_transf_like PF01467.26 KEZ45169.1 - 1.3e-30 106.4 0.0 3.2e-30 105.2 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like TauD PF02668.16 KEZ45170.1 - 3.5e-21 76.2 0.0 5.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEZ45170.1 - 0.0071 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 CsiD Read-through PF16814.5 KEZ45170.1 - 0.019 14.8 0.0 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 Read-through domain Ribosomal_L4 PF00573.22 KEZ45171.1 - 0.23 11.1 0.5 0.45 10.2 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Acetyltransf_10 PF13673.7 KEZ45172.1 - 0.014 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ45172.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family RRM_1 PF00076.22 KEZ45173.1 - 2.4e-35 120.2 0.7 1.3e-16 60.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ45173.1 - 9.4e-12 44.9 0.1 0.00024 21.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KEZ45173.1 - 2.4e-05 24.3 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KEZ45173.1 - 0.057 13.5 0.1 8.6 6.5 0.0 2.6 2 1 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.18 KEZ45175.1 - 1.2e-48 165.6 0.0 2.6e-48 164.5 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ank_4 PF13637.6 KEZ45176.1 - 1.9e-45 152.6 11.7 7.2e-11 42.4 0.1 7.1 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ45176.1 - 4e-39 133.1 8.3 9.6e-14 51.7 0.3 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ45176.1 - 8.8e-32 105.6 6.0 0.00038 20.7 0.0 8.1 7 0 0 7 7 7 7 Ankyrin repeat Ank PF00023.30 KEZ45176.1 - 1.6e-31 107.3 14.4 1.3e-05 25.4 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KEZ45176.1 - 1.5e-17 63.4 4.4 0.00057 20.1 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ45176.1 - 1.9e-09 37.6 0.1 8.5e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ45176.1 - 1.3e-05 25.7 0.9 6.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ45176.1 - 0.0066 16.7 0.1 0.094 13.0 0.0 2.9 3 1 1 4 4 4 1 AAA domain Helo_like_N PF17111.5 KEZ45176.1 - 0.036 13.4 1.4 0.8 9.0 0.0 2.4 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins ATPase_2 PF01637.18 KEZ45176.1 - 0.14 12.1 0.1 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Biotin_carb_C PF02785.19 KEZ45176.1 - 0.2 11.8 0.5 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Biotin carboxylase C-terminal domain Oxysterol_BP PF01237.18 KEZ45177.1 - 2.7e-113 378.6 0.0 7.9e-113 377.1 0.0 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KEZ45177.1 - 7e-37 125.6 0.6 1.7e-36 124.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KEZ45177.1 - 2.7e-07 31.0 0.0 6.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 PH domain ATG7_N PF16420.5 KEZ45178.1 - 7.3e-98 327.9 0.0 9.1e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KEZ45178.1 - 3.2e-45 154.4 0.0 4.8e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family dCMP_cyt_deam_1 PF00383.23 KEZ45179.1 - 8.9e-27 92.9 1.9 1.4e-26 92.3 1.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEZ45179.1 - 4.9e-10 39.3 0.1 8e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase CoaE PF01121.20 KEZ45179.1 - 0.0029 17.3 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KEZ45179.1 - 0.027 15.0 0.0 0.057 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KEZ45179.1 - 0.17 12.3 0.6 0.33 11.4 0.2 1.7 2 0 0 2 2 2 0 AAA domain NKAP PF15692.5 KEZ45179.1 - 0.18 12.6 1.5 0.29 11.9 1.5 1.3 1 0 0 1 1 1 0 NF-kappa-B-activating protein MRC1 PF09444.10 KEZ45180.1 - 5e-40 137.4 23.2 5e-40 137.4 23.2 9.5 8 3 2 10 10 10 1 MRC1-like domain BUD22 PF09073.10 KEZ45180.1 - 0.0024 17.3 30.6 0.0024 17.3 30.6 4.8 3 2 1 4 4 4 1 BUD22 Gln-synt_C PF00120.24 KEZ45181.1 - 4.6e-18 65.3 0.0 2.2e-12 46.7 0.0 2.2 1 1 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KEZ45181.1 - 1.1e-12 47.5 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain APH PF01636.23 KEZ45182.1 - 4.3e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ45182.1 - 4e-05 23.3 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KEZ45182.1 - 0.0028 17.1 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SHNi-TPR PF10516.9 KEZ45183.1 - 4.3e-16 58.1 1.4 1.3e-15 56.6 0.1 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 KEZ45183.1 - 1.3e-05 25.3 6.1 0.0035 17.6 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ45183.1 - 0.0064 17.1 1.9 0.022 15.4 0.1 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ45183.1 - 0.031 14.1 2.6 0.15 11.9 2.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ45183.1 - 0.069 13.6 0.0 0.81 10.2 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ45183.1 - 0.071 13.3 11.8 0.13 12.5 2.5 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ45183.1 - 2.2 8.0 8.4 9.2 6.1 1.5 3.7 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 KEZ45183.1 - 6 7.3 9.6 14 6.2 1.8 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AMPK1_CBM PF16561.5 KEZ45184.1 - 4.3e-07 30.0 0.2 9.2e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 KEZ45184.1 - 0.0038 17.8 0.8 0.0069 16.9 0.0 1.7 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) NACHT PF05729.12 KEZ45185.1 - 0.066 13.1 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Abhydrolase_6 PF12697.7 KEZ45187.1 - 0.0045 17.6 0.2 0.0068 17.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DnaJ PF00226.31 KEZ45188.1 - 9.4e-13 48.1 0.0 1.5e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Ntox15 PF15604.6 KEZ45188.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Novel toxin 15 L27_2 PF09045.10 KEZ45188.1 - 0.33 10.9 1.2 0.61 10.1 1.2 1.4 1 0 0 1 1 1 0 L27_2 MFS_1 PF07690.16 KEZ45189.1 - 4.7e-30 104.7 34.3 8.4e-30 103.9 34.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45189.1 - 8.8e-19 67.7 19.1 5.1e-17 61.9 10.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 KEZ45191.1 - 1.3e-10 41.1 0.0 2.5e-05 23.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45191.1 - 5.7e-05 22.5 0.0 0.0059 15.9 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pro_isomerase PF00160.21 KEZ45192.1 - 2e-48 164.6 0.1 2.9e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KEZ45192.1 - 3.2e-10 39.3 4.4 4.2e-05 23.3 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ45192.1 - 4.7e-10 38.9 2.6 2.7e-05 23.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ45192.1 - 0.00019 21.4 1.8 0.0062 16.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ45192.1 - 0.00065 19.3 6.6 0.008 15.8 0.2 3.7 3 1 1 4 4 4 1 TPR repeat TPR_6 PF13174.6 KEZ45192.1 - 0.0031 18.1 1.6 0.11 13.2 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KEZ45192.1 - 0.0059 17.0 0.4 0.037 14.4 0.1 2.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_16 PF13432.6 KEZ45192.1 - 0.011 16.4 10.1 0.62 10.8 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ45192.1 - 0.094 13.0 2.9 4.6 7.6 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ45192.1 - 0.1 13.5 0.6 0.1 13.5 0.6 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 KEZ45193.1 - 9.1e-54 181.9 0.1 1.1e-53 181.6 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 KEZ45194.1 - 3.1e-88 295.1 28.5 5.1e-88 294.4 28.5 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KEZ45194.1 - 1.3e-41 141.8 9.4 2.9e-41 140.6 9.4 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family HR1 PF02185.16 KEZ45194.1 - 0.0034 17.5 1.2 0.0034 17.5 1.2 2.4 2 1 0 2 2 2 1 Hr1 repeat Syntaxin_2 PF14523.6 KEZ45194.1 - 0.011 16.1 3.5 0.011 16.1 3.5 2.8 2 1 1 3 3 3 0 Syntaxin-like protein DUF2373 PF10180.9 KEZ45194.1 - 0.026 14.4 3.3 0.061 13.2 3.3 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.11 KEZ45194.1 - 0.076 13.1 0.3 0.076 13.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) CorA PF01544.18 KEZ45194.1 - 0.47 9.7 7.1 0.11 11.8 2.5 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 KEZ45194.1 - 0.47 10.9 9.1 1.6 9.3 2.2 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ZapB PF06005.12 KEZ45194.1 - 3 8.4 17.5 0.092 13.2 2.5 2.8 2 0 0 2 2 2 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 KEZ45194.1 - 5.8 7.4 14.0 0.51 10.8 0.8 2.8 2 1 0 2 2 2 0 Snapin/Pallidin HypA PF01155.19 KEZ45195.1 - 0.18 11.8 0.9 0.34 10.9 0.9 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Iso_dh PF00180.20 KEZ45196.1 - 1.1e-72 245.2 0.0 1.2e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.6 KEZ45197.1 - 4.8e-47 161.6 5.7 8e-26 92.2 0.1 3.0 2 1 1 3 3 3 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF3391 PF11871.8 KEZ45197.1 - 0.031 14.8 0.7 0.031 14.8 0.7 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) KIAA1430 PF13879.6 KEZ45197.1 - 0.12 13.2 3.0 2.8 8.8 0.0 2.6 2 0 0 2 2 2 0 KIAA1430 homologue Endosulfine PF04667.17 KEZ45198.1 - 1.3e-27 95.7 0.0 2.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region BESS PF02944.20 KEZ45198.1 - 0.15 12.0 0.3 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 BESS motif HET PF06985.11 KEZ45199.1 - 3.1e-37 128.2 0.0 5.8e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 KEZ45199.1 - 7.1e-16 58.3 4.5 8.4e-09 35.6 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ45199.1 - 3.4e-11 42.6 3.4 4.2e-07 29.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF676 PF05057.14 KEZ45199.1 - 1.3e-05 24.9 0.0 3.4e-05 23.5 0.0 1.6 1 1 1 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ45199.1 - 0.004 17.8 0.0 0.021 15.5 0.0 2.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_14 PF13428.6 KEZ45199.1 - 0.036 14.9 0.5 0.6 11.1 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ45199.1 - 0.16 12.7 0.8 0.65 10.8 0.8 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF829 PF05705.14 KEZ45199.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) PGAP1 PF07819.13 KEZ45199.1 - 0.17 11.5 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Pkinase PF00069.25 KEZ45199.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SPX PF03105.19 KEZ45201.1 - 4.9e-14 53.0 13.0 2e-06 28.0 0.0 4.1 2 1 2 4 4 4 4 SPX domain Fungal_trans PF04082.18 KEZ45202.1 - 3.1e-08 33.0 0.0 4.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45202.1 - 7.7e-07 29.1 10.6 1.5e-06 28.2 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KEZ45203.1 - 0.33 10.9 14.7 0.078 13.0 8.8 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit INCENP_ARK-bind PF03941.15 KEZ45203.1 - 0.73 9.8 8.9 4.7 7.2 1.3 2.9 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region RNA_Me_trans PF04252.13 KEZ45204.1 - 5.9e-83 277.4 0.0 6.6e-83 277.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF2007 PF09413.10 KEZ45205.1 - 0.14 12.3 0.0 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein AbiEii PF08843.11 KEZ45206.1 - 0.00058 19.9 0.0 0.003 17.6 0.0 1.9 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system Peptidase_S10 PF00450.22 KEZ45207.1 - 1.3e-114 383.9 0.1 1.6e-114 383.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CIAPIN1 PF05093.13 KEZ45208.1 - 1.4e-40 137.8 1.9 2.2e-40 137.2 1.9 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KEZ45208.1 - 1.4e-32 112.7 0.0 2.2e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Ceramidase_alk PF04734.13 KEZ45209.1 - 7.5e-216 717.7 0.0 8.7e-216 717.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KEZ45209.1 - 4.6e-56 189.3 0.0 7.7e-56 188.6 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Tctex-1 PF03645.13 KEZ45210.1 - 9.9e-41 138.2 0.0 1.1e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 KEZ45211.1 - 6.6e-17 61.7 5.1 1.4e-16 60.7 2.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.20 KEZ45211.1 - 0.027 14.3 4.5 0.036 13.9 4.5 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF983 PF06170.12 KEZ45211.1 - 0.19 12.2 2.7 6.5 7.2 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF983) CFEM PF05730.11 KEZ45212.1 - 0.033 14.3 12.4 0.069 13.3 12.3 1.6 1 1 0 1 1 1 0 CFEM domain RRM_1 PF00076.22 KEZ45213.1 - 9.1e-17 60.6 0.0 1.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FDF PF09532.10 KEZ45213.1 - 0.023 15.6 1.9 0.035 15.0 1.9 1.2 1 0 0 1 1 1 0 FDF domain Nup35_RRM_2 PF14605.6 KEZ45213.1 - 0.036 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KEZ45213.1 - 0.098 12.4 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KEZ45213.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif GPS2_interact PF15784.5 KEZ45213.1 - 0.11 13.0 4.1 0.23 11.9 4.1 1.5 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain V_ATPase_I PF01496.19 KEZ45213.1 - 0.29 9.0 2.9 0.33 8.8 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 KEZ45213.1 - 0.58 10.4 3.1 0.9 9.8 3.1 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ATP-synt_E PF05680.12 KEZ45213.1 - 0.59 10.5 3.7 0.85 10.0 3.7 1.2 1 0 0 1 1 1 0 ATP synthase E chain OmpH PF03938.14 KEZ45213.1 - 1.4 9.3 7.2 1.8 8.9 7.2 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) HECT PF00632.25 KEZ45214.1 - 6.2e-97 324.8 0.0 8.2e-97 324.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KEZ45214.1 - 7e-33 112.4 19.8 9.2e-13 48.0 3.4 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KEZ45214.1 - 1.1e-20 73.9 0.0 3.3e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 C2 domain PurS PF02700.14 KEZ45214.1 - 0.019 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Oxidored_q6 PF01058.22 KEZ45215.1 - 3.2e-22 78.7 0.0 5.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PMI_typeI PF01238.21 KEZ45217.1 - 4.9e-135 450.5 0.0 5.6e-135 450.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF1325 PF07039.11 KEZ45218.1 - 1.7e-36 125.2 0.1 2.9e-36 124.5 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF5327 PF17261.2 KEZ45218.1 - 0.01 16.5 0.5 0.1 13.4 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF3915 PF13054.6 KEZ45218.1 - 0.02 14.9 3.6 0.039 13.9 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Tudor_3 PF18115.1 KEZ45218.1 - 0.024 14.5 0.1 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Fib_alpha PF08702.10 KEZ45218.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Arf PF00025.21 KEZ45219.1 - 8.9e-76 253.2 0.1 1e-75 253.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KEZ45219.1 - 1.3e-14 54.4 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEZ45219.1 - 5.5e-13 48.8 0.0 6.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KEZ45219.1 - 1.6e-12 47.2 1.8 1.5e-08 34.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KEZ45219.1 - 1.1e-11 44.5 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KEZ45219.1 - 7.5e-11 41.8 0.0 9.4e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEZ45219.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KEZ45219.1 - 0.011 15.1 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Methyltrn_RNA_3 PF02598.17 KEZ45219.1 - 0.032 13.7 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase CRISPR_Cas2 PF09827.9 KEZ45219.1 - 0.077 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 DegQ PF08181.11 KEZ45219.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 DegQ (SacQ) family SpoOE-like PF09388.10 KEZ45219.1 - 0.13 12.1 1.0 0.22 11.4 1.0 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Pkinase PF00069.25 KEZ45220.1 - 1.9e-62 211.1 0.0 4.8e-62 209.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45220.1 - 8.4e-31 107.2 0.0 4.9e-30 104.7 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ45220.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like SelP_N PF04592.14 KEZ45220.1 - 0.88 8.9 16.4 1.8 7.9 16.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Actin PF00022.19 KEZ45221.1 - 7.3e-113 377.2 0.0 4.7e-112 374.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KEZ45221.1 - 0.018 13.9 0.0 0.12 11.2 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein Actin_micro PF17003.5 KEZ45221.1 - 0.028 13.6 0.1 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative actin-like family LMWPc PF01451.21 KEZ45222.1 - 8.1e-39 133.2 0.0 9.3e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.25 KEZ45223.1 - 1.8e-69 234.1 0.0 2.1e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45223.1 - 1.2e-31 110.0 0.0 1.6e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEZ45223.1 - 0.0086 15.1 0.0 0.019 13.9 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KEZ45223.1 - 0.042 13.2 0.1 0.085 12.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KEZ45223.1 - 0.051 13.5 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3455 PF11937.8 KEZ45224.1 - 6.9e-25 88.3 0.0 1.1e-24 87.6 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) NmrA PF05368.13 KEZ45225.1 - 6.3e-38 130.6 0.0 9.3e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ45225.1 - 6e-14 52.3 0.5 9.6e-14 51.7 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ45225.1 - 0.0016 17.5 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KEZ45225.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF1199 PF06712.11 KEZ45225.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) DXP_reductoisom PF02670.16 KEZ45225.1 - 0.12 13.1 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 KEZ45225.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Hexapep PF00132.24 KEZ45226.1 - 1.1e-08 34.4 3.1 4.3e-05 23.1 2.6 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KEZ45226.1 - 2.6e-05 23.8 0.2 0.00079 19.1 0.1 2.7 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF1279 PF06916.13 KEZ45227.1 - 4.3e-24 84.9 0.1 6.6e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3295 PF11702.8 KEZ45228.1 - 5.4 6.3 6.3 6.5 6.0 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) eIF-5_eIF-2B PF01873.17 KEZ45229.1 - 1.9e-42 143.8 0.5 2.9e-42 143.2 0.5 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Med19 PF10278.9 KEZ45229.1 - 0.078 12.9 6.5 0.26 11.2 6.7 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 TF_Zn_Ribbon PF08271.12 KEZ45229.1 - 0.12 11.9 0.6 0.24 10.9 0.6 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 KEZ45229.1 - 0.72 10.2 7.1 1.6 9.2 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain DAO PF01266.24 KEZ45230.1 - 2.5e-38 132.6 3.1 3.1e-38 132.3 3.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ45230.1 - 0.00056 20.1 0.3 0.0017 18.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ45230.1 - 0.00063 18.9 1.0 0.0012 18.0 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KEZ45230.1 - 0.0027 17.0 0.8 1.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ45230.1 - 0.025 13.9 0.3 0.035 13.5 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ45230.1 - 0.043 13.1 0.4 0.1 11.8 0.2 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KEZ45230.1 - 0.17 10.5 1.5 0.36 9.5 1.5 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KEZ45230.1 - 0.17 11.1 1.8 0.32 10.2 1.8 1.4 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.25 KEZ45231.1 - 2.5e-74 250.0 0.0 3.4e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45231.1 - 1.2e-36 126.4 0.0 2.2e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KEZ45231.1 - 6.9e-20 71.7 0.0 2.2e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KEZ45231.1 - 8.5e-16 57.8 0.5 1.6e-15 56.9 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KEZ45231.1 - 3.1e-06 26.7 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KEZ45231.1 - 0.00051 19.7 0.2 0.0014 18.3 0.2 1.7 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KEZ45231.1 - 0.0018 17.3 0.1 0.0028 16.7 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KEZ45231.1 - 0.0044 15.9 0.1 0.0065 15.3 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 KEZ45231.1 - 0.055 13.4 1.3 0.31 10.9 0.5 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KEZ45231.1 - 0.26 10.2 0.2 0.4 9.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NmrA PF05368.13 KEZ45232.1 - 1.1e-26 93.8 0.1 1.3e-26 93.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ45232.1 - 1.2e-08 35.1 0.1 1.1e-07 31.9 0.0 2.3 3 0 0 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 KEZ45232.1 - 8.1e-08 32.0 0.1 3.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ45232.1 - 0.0003 19.9 0.0 0.00041 19.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glu_dehyd_C PF16912.5 KEZ45232.1 - 0.00076 19.0 0.1 0.0016 18.0 0.0 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus GDP_Man_Dehyd PF16363.5 KEZ45232.1 - 0.00078 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KEZ45232.1 - 0.00095 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEZ45232.1 - 0.00098 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KEZ45232.1 - 0.0016 18.8 0.0 0.0033 17.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 KEZ45232.1 - 0.0042 16.6 0.0 0.0089 15.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KEZ45232.1 - 0.0074 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Cas_Cas02710 PF09670.10 KEZ45232.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Sugar_tr PF00083.24 KEZ45233.1 - 3.4e-83 280.0 23.4 7.9e-82 275.5 23.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45233.1 - 1.2e-24 86.9 26.4 1.2e-24 86.9 26.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ45233.1 - 2.7e-09 36.0 1.6 2.7e-09 36.0 1.6 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Trehalase PF01204.18 KEZ45235.1 - 2.6e-180 600.6 0.2 3.1e-180 600.4 0.2 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KEZ45235.1 - 2.9e-09 36.5 0.4 4.9e-09 35.8 0.4 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 KEZ45236.1 - 1.1e-295 981.2 2.8 1.2e-295 981.0 2.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KEZ45236.1 - 2.4e-11 43.6 1.3 1.4e-10 41.0 0.0 2.3 1 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF1712 PF08217.11 KEZ45237.1 - 6e-13 48.2 0.0 3.9e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) RCC1 PF00415.18 KEZ45237.1 - 0.031 14.9 0.0 0.073 13.7 0.0 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat AIM5 PF17050.5 KEZ45238.1 - 9.9e-19 67.9 1.9 9.9e-19 67.9 1.9 2.6 2 1 0 2 2 2 1 Altered inheritance of mitochondria 5 Collagen_mid PF15984.5 KEZ45238.1 - 0.093 12.5 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Bacterial collagen, middle region ZYG-11_interact PF05884.12 KEZ45238.1 - 0.12 11.7 0.6 0.18 11.2 0.6 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 Spt5_N PF11942.8 KEZ45238.1 - 0.4 11.7 3.5 1.2 10.2 3.5 1.9 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_L17 PF01196.19 KEZ45239.1 - 1.9e-30 105.6 0.7 1.9e-30 105.6 0.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 PIN_5 PF08745.11 KEZ45239.1 - 0.11 11.9 1.4 0.38 10.1 0.1 1.9 2 0 0 2 2 2 0 PINc domain ribonuclease UTP25 PF06862.12 KEZ45240.1 - 1.6e-195 650.4 0.4 1.9e-195 650.1 0.4 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KEZ45240.1 - 0.0035 17.1 0.0 0.11 12.2 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase SUZ PF12752.7 KEZ45241.1 - 1.2e-15 58.0 4.2 1.2e-15 58.0 4.2 3.1 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 KEZ45241.1 - 9.2e-09 35.2 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 R3H domain Glyco_transf_8 PF01501.20 KEZ45241.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 KRTAP7 PF15034.6 KEZ45242.1 - 0.068 14.1 1.6 0.12 13.4 1.6 1.4 1 0 0 1 1 1 0 KRTAP type 7 family LRS4 PF10422.9 KEZ45242.1 - 0.47 10.0 3.3 0.4 10.2 1.8 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 NAD_binding_5 PF07994.12 KEZ45243.1 - 5.4e-146 486.1 0.1 7.3e-146 485.6 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KEZ45243.1 - 2.8e-45 153.0 0.5 6.9e-45 151.8 0.5 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.22 KEZ45244.1 - 1.1e-22 80.0 17.0 1.4e-11 44.4 4.3 3.1 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 KEZ45244.1 - 0.17 11.6 0.9 0.47 10.2 0.1 2.1 2 0 0 2 2 2 0 WRC PC4 PF02229.16 KEZ45245.1 - 1.1e-23 82.6 0.4 3.2e-23 81.1 0.3 1.8 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) MFS_1 PF07690.16 KEZ45246.1 - 7.7e-21 74.4 17.6 5.6e-13 48.6 7.5 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45246.1 - 5.7e-11 41.9 4.9 5.7e-11 41.9 4.9 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter DUF979 PF06166.12 KEZ45246.1 - 0.0015 17.7 0.3 1.2 8.2 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF979) 4HBT_2 PF13279.6 KEZ45247.1 - 0.00013 22.5 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Hydantoinase_B PF02538.14 KEZ45248.1 - 4.2e-219 728.2 0.0 5.4e-219 727.9 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KEZ45248.1 - 1.5e-80 270.6 0.0 7.8e-61 205.9 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ45248.1 - 1.2e-60 204.3 0.0 2.3e-60 203.3 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region GCS PF03074.16 KEZ45250.1 - 5.4e-175 582.1 0.0 6.5e-175 581.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase HET PF06985.11 KEZ45251.1 - 3.3e-23 82.7 0.0 6.9e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RTTN_N PF14726.6 KEZ45251.1 - 0.14 13.0 0.4 0.28 12.0 0.4 1.4 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning Cyclin PF08613.11 KEZ45252.1 - 9.7e-11 42.3 0.2 2.1e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KEZ45252.1 - 0.0033 17.2 0.1 0.0056 16.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs7 PF12271.8 KEZ45253.1 - 4e-126 420.2 18.3 4.6e-126 420.0 18.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KEZ45253.1 - 3.3 8.0 10.1 0.07 13.4 1.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3716 PF12511.8 KEZ45254.1 - 2.9e-09 36.8 5.9 5.1e-09 36.0 5.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Glyco_hydro_47 PF01532.20 KEZ45255.1 - 2.2e-166 554.3 0.0 2.6e-166 554.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KEZ45255.1 - 0.052 12.6 2.8 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 PX PF00787.24 KEZ45258.1 - 1.1e-18 67.3 0.2 2e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 PX domain Ribosomal_L27A PF00828.19 KEZ45259.1 - 1.1e-31 110.2 0.5 1.7e-31 109.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Lactonase PF10282.9 KEZ45260.1 - 1.1e-51 176.2 0.0 1.4e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.16 KEZ45260.1 - 0.038 12.5 0.0 4 5.9 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain Glyco_hydro_16 PF00722.21 KEZ45261.1 - 8.5e-45 152.4 9.2 1.3e-44 151.7 9.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KEZ45261.1 - 0.012 16.0 12.7 0.031 14.8 12.7 1.6 1 0 0 1 1 1 0 Chitin recognition protein Myb_DNA-binding PF00249.31 KEZ45262.1 - 5.1e-16 58.6 2.0 4.3e-09 36.4 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEZ45262.1 - 4e-09 36.6 0.7 0.00052 20.2 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KEZ45262.1 - 0.29 11.3 2.0 0.31 11.2 0.0 2.0 3 0 0 3 3 3 0 Rap1 Myb domain Myb_DNA-binding PF00249.31 KEZ45263.1 - 0.00054 20.1 0.9 0.0015 18.7 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEZ45263.1 - 0.011 16.0 0.1 0.044 14.1 0.2 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain ILVD_EDD PF00920.21 KEZ45264.1 - 2.4e-210 699.6 0.1 2.8e-210 699.3 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.16 KEZ45265.1 - 1.6e-94 316.8 5.7 3.1e-94 315.9 5.7 1.4 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4974 PF16344.5 KEZ45265.1 - 0.03 14.3 0.3 0.086 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) COX5B PF01215.19 KEZ45266.1 - 2e-59 198.9 0.0 2.6e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.10 KEZ45266.1 - 0.07 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain 4HBT_3 PF13622.6 KEZ45267.1 - 3.7e-21 76.5 0.3 4.8e-21 76.1 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Cullin_binding PF03556.15 KEZ45268.1 - 9.2e-35 119.7 2.6 1.4e-34 119.1 2.6 1.3 1 0 0 1 1 1 1 Cullin binding Ribosomal_S6 PF01250.17 KEZ45269.1 - 1.1e-21 76.9 0.0 1.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 SQS_PSY PF00494.19 KEZ45270.1 - 5e-57 193.4 0.2 6.1e-57 193.1 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 KEZ45271.1 - 5.5e-76 255.5 0.0 9e-76 254.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KEZ45271.1 - 7.6e-26 89.9 0.0 1.4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KEZ45271.1 - 3.2e-17 62.9 0.0 6.5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ45271.1 - 1.2e-05 25.4 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KEZ45271.1 - 2.4e-05 24.1 11.2 4.7e-05 23.2 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ45271.1 - 5.4e-05 22.9 6.0 0.00011 22.0 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEZ45271.1 - 0.0011 18.7 9.3 0.0021 17.9 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEZ45271.1 - 0.0038 17.5 10.4 0.0094 16.3 10.4 1.7 1 0 0 1 1 1 1 Ring finger domain UBA_4 PF14555.6 KEZ45271.1 - 0.0057 16.4 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain ERCC3_RAD25_C PF16203.5 KEZ45271.1 - 0.014 14.7 0.2 0.024 13.9 0.2 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 KEZ45271.1 - 0.027 14.4 8.3 0.067 13.2 8.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEZ45271.1 - 0.071 13.1 8.9 0.16 12.0 8.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Retinal PF15449.6 KEZ45273.1 - 3.8 5.2 18.2 4.8 4.8 18.2 1.1 1 0 0 1 1 1 0 Retinal protein Asp PF00026.23 KEZ45274.1 - 1.5e-51 175.7 0.0 1.8e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ45274.1 - 3.1e-13 50.3 0.8 1e-11 45.4 0.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.18 KEZ45275.1 - 9.3e-21 74.0 0.1 2.1e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEZ45275.1 - 2.4e-08 34.0 13.0 0.00042 20.6 1.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ45275.1 - 5.8e-06 26.5 12.4 1e-05 25.7 6.6 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ45275.1 - 0.00054 20.6 12.7 0.048 14.5 1.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.12 KEZ45275.1 - 0.64 10.3 2.0 1.5 9.1 2.0 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 KEZ45275.1 - 1.2 9.5 3.5 0.44 10.9 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GTP_EFTU PF00009.27 KEZ45276.1 - 9.8e-18 64.4 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KEZ45276.1 - 3.4e-09 37.0 1.7 1.1e-08 35.3 1.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KEZ45276.1 - 1.4e-05 25.4 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain RsgA_GTPase PF03193.16 KEZ45276.1 - 0.00031 20.7 0.7 0.36 10.7 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KEZ45276.1 - 0.0021 18.1 0.2 0.0056 16.8 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KEZ45276.1 - 0.0097 15.7 0.1 1.8 8.3 0.0 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 KEZ45276.1 - 0.058 13.6 0.1 0.52 10.5 0.0 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phage_lysis PF03245.13 KEZ45276.1 - 0.063 13.4 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein Dynamin_N PF00350.23 KEZ45276.1 - 0.07 13.2 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Dynamin family Arrestin_C PF02752.22 KEZ45277.1 - 6.9e-17 62.2 1.1 1.8e-16 60.8 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KEZ45277.1 - 8.9e-05 22.6 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LSM PF01423.22 KEZ45278.1 - 3e-18 65.3 0.1 4.3e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain PIG-L PF02585.17 KEZ45279.1 - 3.7e-26 92.3 0.0 5.2e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PBP_N PF17093.5 KEZ45280.1 - 0.056 13.7 0.5 0.16 12.3 0.5 1.8 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus CD52 PF15116.6 KEZ45280.1 - 6.5 6.9 5.2 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen DUF202 PF02656.15 KEZ45281.1 - 0.07 13.6 0.5 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Cas_Cas1 PF01867.16 KEZ45281.1 - 0.084 12.0 1.5 1.5 7.9 0.2 2.1 2 0 0 2 2 2 0 CRISPR associated protein Cas1 Flu_M2 PF00599.17 KEZ45281.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Helo_like_N PF17111.5 KEZ45281.1 - 0.27 10.6 2.6 0.45 9.8 0.1 2.4 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins SlyX PF04102.12 KEZ45281.1 - 1.3 9.7 6.7 0.28 11.8 0.6 2.7 3 0 0 3 3 3 0 SlyX SH3-RhoG_link PF16609.5 KEZ45282.1 - 0.022 14.5 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region DUF3391 PF11871.8 KEZ45282.1 - 0.079 13.5 7.4 0.31 11.6 7.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) COG2 PF06148.11 KEZ45282.1 - 0.12 12.4 2.6 0.14 12.3 1.0 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 VGCC_beta4Aa_N PF12052.8 KEZ45282.1 - 6.6 6.9 9.8 0.68 10.1 0.4 3.1 3 0 0 3 3 3 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal MscS_porin PF12795.7 KEZ45283.1 - 0.0021 17.7 5.4 0.0028 17.2 5.4 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Resolvase PF00239.21 KEZ45283.1 - 0.028 14.5 1.4 0.077 13.1 1.4 1.8 1 1 0 1 1 1 0 Resolvase, N terminal domain mRNA_stabil PF13929.6 KEZ45283.1 - 0.035 13.1 0.2 0.048 12.7 0.2 1.1 1 0 0 1 1 1 0 mRNA stabilisation TT_ORF2 PF02957.15 KEZ45283.1 - 0.066 14.1 0.0 0.08 13.9 0.0 1.1 1 0 0 1 1 1 0 TT viral ORF2 Nha1_C PF08619.10 KEZ45285.1 - 1e-112 377.7 24.2 1.2e-112 377.5 24.2 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KEZ45285.1 - 1.3e-79 267.8 21.5 1.5e-79 267.5 21.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KEZ45285.1 - 0.029 14.5 0.4 0.029 14.5 0.4 2.4 2 0 0 2 2 2 0 YrhC-like protein FlgD_ig PF13860.6 KEZ45285.1 - 0.069 13.0 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 FlgD Ig-like domain DUF21 PF01595.20 KEZ45285.1 - 0.3 10.8 4.6 1.1 9.0 4.6 1.9 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain FAD_binding_4 PF01565.23 KEZ45288.1 - 4.9e-22 78.2 0.6 8.4e-22 77.4 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ45288.1 - 1.5e-07 31.4 1.0 3e-07 30.4 1.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Tom22 PF04281.13 KEZ45290.1 - 1.3e-45 154.6 0.1 2e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Cofilin_ADF PF00241.20 KEZ45291.1 - 0.0081 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MMS1_N PF10433.9 KEZ45292.1 - 1.2e-150 502.3 0.0 2.4e-150 501.4 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KEZ45292.1 - 1.5e-100 336.6 0.0 4.9e-100 335.0 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 KEZ45292.1 - 0.0048 17.2 0.0 0.29 11.4 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 KEZ45292.1 - 0.038 13.3 0.0 4 6.6 0.0 3.3 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller PP2C PF00481.21 KEZ45293.1 - 2.4e-65 220.7 0.0 4.3e-52 177.3 0.1 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C Snf7 PF03357.21 KEZ45294.1 - 1.9e-35 122.0 17.0 1.9e-35 122.0 17.0 1.5 2 0 0 2 2 2 1 Snf7 CCAP PF11105.8 KEZ45294.1 - 0.0032 17.4 0.5 0.0064 16.4 0.5 1.6 1 0 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a RTX PF02382.15 KEZ45294.1 - 0.049 13.3 0.7 0.072 12.8 0.7 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein DUF1993 PF09351.10 KEZ45294.1 - 0.4 10.8 3.5 0.58 10.3 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Spc24 PF08286.11 KEZ45294.1 - 5.3 7.3 9.1 0.72 10.1 3.1 2.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Dynamin_N PF00350.23 KEZ45295.1 - 7.2e-19 68.4 0.0 2.8e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KEZ45295.1 - 1.9e-09 37.6 0.0 1e-08 35.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEZ45295.1 - 5.7e-06 26.0 0.8 0.00016 21.2 1.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Lipase_GDSL_3 PF14606.6 KEZ45295.1 - 0.006 16.7 0.8 9.8 6.3 0.0 3.9 4 0 0 4 4 4 1 GDSL-like Lipase/Acylhydrolase family TsaE PF02367.17 KEZ45295.1 - 0.02 14.9 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 KEZ45295.1 - 0.026 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 KEZ45295.1 - 0.083 13.4 0.0 0.25 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2205 PF10224.9 KEZ45295.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Short coiled-coil protein WD40 PF00400.32 KEZ45296.1 - 2.5e-37 126.2 24.2 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ45296.1 - 1.9e-14 53.7 0.1 0.00032 21.0 0.1 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ45296.1 - 1.1e-05 24.6 0.2 0.34 9.8 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEZ45296.1 - 3.3e-05 23.9 0.0 0.039 13.8 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KEZ45296.1 - 0.00084 18.7 0.1 0.047 13.0 0.0 2.9 3 1 1 4 4 4 1 WD40-like domain GrpE PF01025.19 KEZ45296.1 - 0.11 12.1 1.1 0.17 11.5 1.1 1.2 1 0 0 1 1 1 0 GrpE Spc24 PF08286.11 KEZ45296.1 - 0.21 11.8 0.7 26 5.1 0.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.9 KEZ45296.1 - 1.1 8.3 4.3 1.5 7.8 4.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phosducin PF02114.16 KEZ45297.1 - 1.2e-09 37.6 0.0 1.1e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 Phosducin Ran_BP1 PF00638.18 KEZ45298.1 - 1.6e-49 167.2 2.5 3e-49 166.3 2.5 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 KEZ45298.1 - 0.0031 17.4 0.3 0.012 15.5 0.3 1.8 1 1 0 1 1 1 1 WH1 domain PS-DH PF14765.6 KEZ45298.1 - 0.015 14.5 0.5 0.028 13.7 0.5 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase DUF4358 PF14270.6 KEZ45298.1 - 0.078 13.3 0.5 0.078 13.3 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) YEATS PF03366.16 KEZ45299.1 - 6.3e-21 74.1 0.1 1.5e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KEZ45299.1 - 0.0019 18.3 2.7 0.025 14.7 2.7 2.4 1 1 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Zn_clus PF00172.18 KEZ45300.1 - 3.6e-07 30.2 11.9 5.6e-07 29.6 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 KEZ45301.1 - 1.1e-43 149.4 0.0 1.5e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KEZ45301.1 - 5.3e-10 39.1 1.3 1.4e-09 37.7 0.1 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KEZ45301.1 - 1.7e-06 28.9 0.2 5.5e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SAM_2 PF07647.17 KEZ45302.1 - 4.5e-16 58.7 0.0 9.4e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KEZ45302.1 - 1.6e-13 50.9 0.0 3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KEZ45302.1 - 2e-11 44.4 0.0 4.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KEZ45302.1 - 0.033 14.2 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ETS_PEA3_N PF04621.13 KEZ45302.1 - 0.79 9.5 9.6 1.7 8.4 9.6 1.8 1 1 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Pyr_redox_2 PF07992.14 KEZ45304.1 - 6e-53 180.0 0.1 7.5e-53 179.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ45304.1 - 5.8e-14 52.4 0.0 2.2e-12 47.4 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ45304.1 - 0.0011 18.3 0.1 0.68 9.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 KEZ45304.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal SH3_1 PF00018.28 KEZ45305.1 - 0.00049 19.7 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF4878 PF12870.7 KEZ45305.1 - 0.027 14.8 3.0 0.1 12.9 3.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) SH3_9 PF14604.6 KEZ45305.1 - 0.032 14.1 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain ELFV_dehydrog PF00208.21 KEZ45307.1 - 3.8e-64 216.7 0.0 5.9e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KEZ45307.1 - 3.2e-18 64.8 0.0 1.3e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KEZ45307.1 - 0.00062 19.7 0.0 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.19 KEZ45308.1 - 2.6e-05 23.4 0.0 0.00035 19.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KEZ45308.1 - 0.00054 18.6 0.0 0.00077 18.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KEZ45308.1 - 0.026 13.8 0.0 0.053 12.8 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.19 KEZ45308.1 - 0.22 10.1 0.0 0.45 9.0 0.0 1.4 2 0 0 2 2 2 0 Serine hydroxymethyltransferase Bac_rhamnosid6H PF17389.2 KEZ45309.1 - 4.1e-17 62.5 2.9 2e-16 60.2 1.2 2.4 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KEZ45309.1 - 3.2e-06 26.8 0.4 6.4e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KEZ45309.1 - 5.4e-06 25.6 0.0 8.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF608 PF04685.13 KEZ45309.1 - 0.0006 19.1 0.2 0.001 18.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Bac_rhamnosid PF05592.11 KEZ45309.1 - 0.0017 18.3 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_36 PF17167.4 KEZ45309.1 - 0.092 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Ribosomal_L32e PF01655.18 KEZ45310.1 - 2.3e-48 163.1 2.0 3.6e-48 162.5 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L32 DnaJ_C PF01556.18 KEZ45310.1 - 1.3e-33 116.2 1.0 1.9e-33 115.7 0.2 1.7 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 KEZ45310.1 - 1e-24 86.4 3.8 1.9e-24 85.5 3.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KEZ45310.1 - 4.2e-14 52.6 16.1 7.2e-14 51.9 16.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KEZ45310.1 - 0.00025 21.0 10.2 0.088 12.8 2.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KEZ45310.1 - 0.059 13.4 8.6 0.46 10.5 1.0 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 KEZ45310.1 - 0.17 12.4 5.4 2 9.0 0.9 2.5 2 0 0 2 2 2 0 Cytochrome c3 zf-RING_10 PF16685.5 KEZ45310.1 - 0.44 10.7 8.1 1.9 8.7 0.9 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 KEZ45310.1 - 9.8 6.3 9.8 16 5.6 1.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon tRNA-synt_1c PF00749.21 KEZ45311.1 - 1.2e-60 205.0 0.0 2.3e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HET PF06985.11 KEZ45311.1 - 4e-33 114.8 0.5 1e-32 113.5 0.5 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 KEZ45312.1 - 2.1e-16 59.0 8.5 1.6e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ45312.1 - 1.8e-15 55.7 8.6 1.9e-06 27.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ45312.1 - 1.1e-11 44.8 0.6 2.1e-07 31.1 0.1 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ45312.1 - 1.7e-09 37.2 5.0 6.8e-06 25.9 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ45312.1 - 8.4e-09 35.5 0.9 0.084 13.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ45312.1 - 4.7e-08 32.5 0.7 3.7e-06 26.6 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ45312.1 - 1.4e-07 31.1 2.2 1.1e-05 24.9 0.1 3.8 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 KEZ45312.1 - 1.4e-06 28.2 0.2 2.5e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.6 KEZ45312.1 - 3.6e-06 27.0 0.2 0.15 12.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ45312.1 - 8.3e-05 22.7 0.8 0.26 11.8 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ45312.1 - 0.00015 22.3 0.7 0.0072 16.9 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ45312.1 - 0.00096 19.0 7.2 0.16 11.9 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ45312.1 - 0.0052 17.5 0.3 0.19 12.6 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.9 KEZ45312.1 - 0.046 12.5 0.1 0.081 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_4 PF07721.14 KEZ45312.1 - 0.095 13.4 0.1 45 5.1 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ45312.1 - 0.098 13.2 0.0 1.3 9.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat HMA PF00403.26 KEZ45313.1 - 3.1e-13 50.0 0.1 5.9e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KEZ45313.1 - 8.4e-09 35.7 0.0 1.3e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chordopox_RPO7 PF05864.12 KEZ45313.1 - 0.18 12.0 0.4 3.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ribosomal_L13 PF00572.18 KEZ45314.1 - 8.8e-39 132.6 0.0 1.6e-38 131.8 0.0 1.3 2 0 0 2 2 2 1 Ribosomal protein L13 Uricase PF01014.18 KEZ45315.1 - 1.9e-77 257.9 0.6 2e-41 141.3 0.1 2.0 2 0 0 2 2 2 2 Uricase DUF4699 PF15770.5 KEZ45315.1 - 0.046 13.5 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) DICT PF10069.9 KEZ45315.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.8 1 1 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system HET PF06985.11 KEZ45316.1 - 1.7e-20 73.9 0.0 2.7e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PDH PF02153.17 KEZ45317.1 - 4.5e-13 48.8 0.0 6.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KEZ45317.1 - 1.1e-06 28.9 0.1 2.3e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ45317.1 - 1e-05 26.0 0.1 2.3e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 KEZ45317.1 - 0.00023 20.6 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KEZ45317.1 - 0.0012 18.5 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KEZ45317.1 - 0.0038 17.5 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KEZ45317.1 - 0.019 14.8 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KEZ45317.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 KEZ45317.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain Mpv17_PMP22 PF04117.12 KEZ45318.1 - 9.8e-11 41.7 5.0 1.9e-10 40.8 3.2 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family Phos_pyr_kin PF08543.12 KEZ45319.1 - 9.4e-74 247.9 1.1 1.3e-73 247.5 1.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KEZ45319.1 - 5e-48 163.7 0.1 7.8e-48 163.1 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KEZ45319.1 - 8.6e-09 35.1 0.1 6.5e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase HK PF02110.15 KEZ45319.1 - 0.0045 16.4 0.6 0.23 10.8 0.1 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KEZ45319.1 - 0.0096 15.4 0.6 0.14 11.6 0.2 2.3 2 0 0 2 2 2 1 Carbohydrate kinase CbiK PF06180.11 KEZ45319.1 - 0.034 13.5 0.1 0.097 12.0 0.1 1.7 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DEAD PF00270.29 KEZ45320.1 - 8.7e-49 165.7 0.0 6.9e-48 162.7 0.0 2.0 1 1 2 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ45320.1 - 1.4e-24 86.6 0.4 2.5e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ45320.1 - 8.1e-05 22.7 0.0 0.00022 21.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GRP PF07172.11 KEZ45320.1 - 0.021 15.5 1.7 0.021 15.5 1.7 3.4 2 1 1 3 3 3 0 Glycine rich protein family AAA_19 PF13245.6 KEZ45320.1 - 0.1 12.9 0.0 19 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain UL17 PF17640.2 KEZ45320.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized UL17 Catalase-rel PF06628.12 KEZ45320.1 - 0.16 12.2 0.2 3.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF5335 PF17269.2 KEZ45320.1 - 0.18 11.6 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) FOXP-CC PF16159.5 KEZ45321.1 - 0.14 12.8 0.4 0.32 11.7 0.4 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KEZ45321.1 - 0.2 12.2 0.1 0.42 11.2 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Ribosomal_S9 PF00380.19 KEZ45322.1 - 1.8e-28 99.5 0.0 2.4e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RICTOR_N PF14664.6 KEZ45323.1 - 7.8e-96 321.3 0.0 6.9e-92 308.3 0.0 2.7 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KEZ45323.1 - 1e-38 131.3 0.0 1.2e-35 121.4 0.0 4.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KEZ45323.1 - 8.3e-38 129.1 0.3 1.6e-36 125.0 0.0 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KEZ45323.1 - 1.1e-28 99.2 0.4 8.6e-27 93.2 0.1 3.5 4 0 0 4 4 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KEZ45323.1 - 2.2e-16 59.7 12.4 5.7e-16 58.4 12.4 1.8 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.9 KEZ45323.1 - 0.00017 20.3 0.2 0.18 10.2 0.0 3.4 4 0 0 4 4 4 2 Proteasome non-ATPase 26S subunit Uds1 PF15456.6 KEZ45323.1 - 0.0036 17.4 7.7 0.0089 16.2 7.7 1.7 1 0 0 1 1 1 1 Up-regulated During Septation DUF724 PF05266.14 KEZ45323.1 - 0.14 12.0 4.3 0.31 10.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KEZ45323.1 - 1.2 8.4 6.0 0.75 9.1 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4611 PF15387.6 KEZ45323.1 - 2.5 8.4 8.5 2.4 8.4 4.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-K PF11802.8 KEZ45323.1 - 3.5 7.1 8.1 6.5 6.3 8.1 1.3 1 0 0 1 1 1 0 Centromere-associated protein K FemAB PF02388.16 KEZ45323.1 - 8.5 5.1 7.6 14 4.5 7.6 1.2 1 0 0 1 1 1 0 FemAB family Rad9 PF04139.13 KEZ45324.1 - 8.8e-25 87.6 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 Alk_phosphatase PF00245.20 KEZ45325.1 - 4.6e-105 351.9 0.0 6e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KEZ45325.1 - 7.5e-05 22.2 0.1 0.00017 21.1 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Abhydrolase_6 PF12697.7 KEZ45326.1 - 7e-17 62.8 0.1 1.2e-16 62.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ45326.1 - 3.2e-16 59.8 0.0 1.3e-14 54.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ45326.1 - 1.5e-13 50.6 0.0 1.2e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 KEZ45326.1 - 4.4e-09 36.2 0.0 9.3e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PGAP1 PF07819.13 KEZ45326.1 - 9.8e-06 25.4 0.1 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 KEZ45326.1 - 0.00028 21.1 0.1 0.0005 20.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Y_phosphatase PF00102.27 KEZ45326.1 - 0.0044 16.6 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF900 PF05990.12 KEZ45326.1 - 0.0082 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PTPlike_phytase PF14566.6 KEZ45326.1 - 0.009 16.1 0.1 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate LCAT PF02450.15 KEZ45326.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PAF-AH_p_II PF03403.13 KEZ45326.1 - 0.015 13.8 0.1 3.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Ser_hydrolase PF06821.13 KEZ45326.1 - 0.029 14.2 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_2 PF02230.16 KEZ45326.1 - 0.049 13.4 0.0 2 8.1 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 KEZ45326.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 KEZ45326.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KEZ45326.1 - 0.082 12.8 0.2 0.22 11.4 0.1 1.7 1 1 1 2 2 2 0 Lipase (class 3) VirJ PF06057.11 KEZ45326.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_4 PF08386.10 KEZ45326.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 KEZ45326.1 - 0.2 11.3 0.0 1.7 8.3 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ribosomal_L34e PF01199.18 KEZ45327.1 - 4.8e-37 126.2 1.4 9e-37 125.3 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L34e Ricin_B_lectin PF00652.22 KEZ45328.1 - 7e-15 55.4 0.1 4.6e-06 26.9 0.0 4.3 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain APOBEC3 PF18771.1 KEZ45329.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 APOBEC3 Ribosomal_S19e PF01090.19 KEZ45330.1 - 7.2e-60 200.6 0.2 8.1e-60 200.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e MDM10 PF12519.8 KEZ45331.1 - 1.2e-155 519.0 0.1 3.4e-155 517.5 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Adeno_PV PF03910.13 KEZ45331.1 - 0.033 12.9 0.6 0.052 12.2 0.6 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV PAP2_3 PF14378.6 KEZ45332.1 - 3.8e-38 131.1 15.6 1.7e-28 99.7 3.1 2.7 2 1 1 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 KEZ45332.1 - 0.0061 16.3 3.2 0.0061 16.3 3.2 2.5 3 0 0 3 3 3 1 PAP2 superfamily Mid2 PF04478.12 KEZ45332.1 - 0.024 14.5 0.1 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor PAP2_C PF14360.6 KEZ45332.1 - 0.2 12.2 1.9 0.41 11.2 0.4 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal LDB19 PF13002.7 KEZ45333.1 - 3.4e-35 121.5 0.2 4.8e-35 121.0 0.2 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Spo0M PF07070.11 KEZ45333.1 - 0.019 14.5 0.2 0.04 13.5 0.0 1.5 2 0 0 2 2 2 0 SpoOM protein Arrestin_N PF00339.29 KEZ45333.1 - 0.032 14.3 0.1 0.28 11.3 0.1 2.3 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Roughex PF06020.11 KEZ45333.1 - 0.039 13.0 1.6 0.062 12.4 1.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF4449 PF14613.6 KEZ45334.1 - 3e-49 167.3 0.6 3e-49 167.3 0.6 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) UPRTase PF14681.6 KEZ45335.1 - 3.8e-70 235.6 0.0 4.3e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KEZ45335.1 - 0.00013 21.6 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 KEZ45335.1 - 0.0046 16.3 0.3 0.11 11.9 0.1 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase PRTase_2 PF15609.6 KEZ45335.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase Pribosyl_synth PF14572.6 KEZ45335.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain DNA_ligase_A_M PF01068.21 KEZ45336.1 - 2.2e-42 145.1 0.1 7.3e-42 143.3 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KEZ45336.1 - 9.4e-41 140.0 0.0 1.6e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KEZ45336.1 - 1.1e-16 61.6 0.0 2.4e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 KEZ45336.1 - 6.7e-16 58.5 0.0 2.2e-09 37.6 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KEZ45336.1 - 7e-16 58.6 0.2 3.1e-15 56.6 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KEZ45336.1 - 9.3e-09 35.6 0.0 1e-07 32.2 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KEZ45336.1 - 0.0044 17.1 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 KEZ45336.1 - 0.0084 16.4 0.0 5 7.5 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain mRNA_cap_enzyme PF01331.19 KEZ45336.1 - 0.019 14.8 0.0 0.27 11.0 0.0 2.4 2 1 0 2 2 2 0 mRNA capping enzyme, catalytic domain DUF4652 PF15525.6 KEZ45336.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) LigB PF02900.18 KEZ45337.1 - 4.3e-35 121.1 0.0 8e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Amidohydro_3 PF07969.11 KEZ45337.1 - 8.6e-16 58.5 0.6 5.9e-10 39.2 0.0 3.4 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 KEZ45337.1 - 3.2e-12 46.4 0.1 7.5e-10 38.6 0.0 3.5 4 0 0 4 4 4 1 Amidohydrolase family GST_C_3 PF14497.6 KEZ45338.1 - 6.9e-31 106.4 0.0 1.3e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEZ45338.1 - 0.00018 21.6 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEZ45338.1 - 0.0076 16.6 0.0 0.097 13.0 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ45338.1 - 0.024 14.6 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MAP65_ASE1 PF03999.12 KEZ45339.1 - 2.9e-81 274.0 6.3 6.4e-81 272.8 6.2 1.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.11 KEZ45339.1 - 0.37 8.7 3.9 2.8 5.8 0.1 2.5 2 1 0 2 2 2 0 Prominin APG6_N PF17675.1 KEZ45339.1 - 2.2 8.8 25.2 0.19 12.2 4.8 3.6 3 0 0 3 3 3 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 KEZ45339.1 - 2.7 8.4 6.0 2.9 8.2 0.0 3.7 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_M28 PF04389.17 KEZ45340.1 - 6.2e-43 146.8 0.0 9.4e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEZ45340.1 - 4.6e-12 45.8 0.1 1.3e-11 44.4 0.1 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEZ45340.1 - 4.8e-06 26.4 0.0 1.9e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 GMC_oxred_N PF00732.19 KEZ45341.1 - 1.3e-47 162.6 0.0 2e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ45341.1 - 1.3e-23 84.1 0.1 4.6e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 KEZ45341.1 - 0.011 15.3 2.6 0.033 13.8 2.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KEZ45341.1 - 0.012 15.9 0.3 0.042 14.1 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 KEZ45341.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 KEZ45341.1 - 0.032 14.5 0.1 0.092 13.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ45341.1 - 0.047 12.8 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KEZ45341.1 - 0.067 12.4 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ45341.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DOT1 PF08123.13 KEZ45342.1 - 8.7e-76 254.0 0.0 1.3e-75 253.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 KEZ45342.1 - 0.0062 17.2 0.1 0.014 16.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ45342.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain ATG16 PF08614.11 KEZ45343.1 - 5.2e-52 177.0 12.5 5.9e-52 176.8 12.5 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 KEZ45343.1 - 0.0027 16.9 13.2 0.026 13.6 9.9 2.0 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region POTRA_TamA_1 PF17243.2 KEZ45343.1 - 0.016 15.3 0.6 0.044 13.9 0.1 2.1 2 0 0 2 2 2 0 POTRA domain TamA domain 1 BBS2_C PF14782.6 KEZ45343.1 - 0.037 12.8 4.0 0.054 12.3 4.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF5094 PF17015.5 KEZ45343.1 - 0.41 10.7 6.8 0.2 11.7 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) DUF4472 PF14739.6 KEZ45343.1 - 0.47 11.2 12.3 0.24 12.2 8.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) UPF0242 PF06785.11 KEZ45343.1 - 0.86 9.7 8.8 1.6 8.8 8.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ndc1_Nup PF09531.10 KEZ45343.1 - 0.92 8.1 4.5 1 7.9 4.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3810 PF12725.7 KEZ45343.1 - 0.93 8.8 5.6 5.9 6.1 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) APG6_N PF17675.1 KEZ45343.1 - 1.4 9.4 21.7 3.1 8.3 16.4 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 KEZ45343.1 - 1.8 8.6 6.9 1.1 9.4 4.9 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Vps16_N PF04841.13 KEZ45344.1 - 5.3e-89 298.8 0.0 9.9e-89 297.9 0.0 1.4 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 KEZ45344.1 - 1.7e-82 277.1 0.0 2.5e-82 276.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KEZ45344.1 - 0.00092 19.5 0.0 0.13 12.6 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 KEZ45345.1 - 1.3e-16 60.6 0.0 2.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KEZ45345.1 - 1.5e-13 50.2 6.2 2.6e-13 49.5 6.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KEZ45345.1 - 3.1e-07 30.6 9.5 5.3e-07 29.9 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 KEZ45345.1 - 0.005 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KEZ45345.1 - 0.0053 16.6 9.4 0.0091 15.9 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEZ45345.1 - 0.0067 16.7 6.3 0.018 15.3 6.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEZ45345.1 - 0.0084 16.0 6.8 0.014 15.4 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.29 KEZ45345.1 - 0.016 15.1 5.2 0.029 14.2 5.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KEZ45345.1 - 0.053 13.6 9.1 0.11 12.5 9.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KEZ45345.1 - 0.071 13.0 9.2 0.13 12.1 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KEZ45345.1 - 0.12 12.3 5.2 0.18 11.7 5.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEZ45345.1 - 0.12 12.4 2.3 0.23 11.5 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger OrfB_Zn_ribbon PF07282.11 KEZ45345.1 - 0.69 9.9 2.5 6.9 6.7 0.8 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_4 PF15227.6 KEZ45345.1 - 0.72 10.1 6.8 1.6 8.9 6.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KEZ45345.1 - 3.6 8.0 5.3 6.4 7.2 5.3 1.4 1 0 0 1 1 1 0 RING-like domain Peptidase_M16_C PF05193.21 KEZ45347.1 - 9.3e-53 179.0 0.0 1.8e-52 178.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KEZ45347.1 - 2.7e-41 141.0 0.0 1.1e-40 139.0 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Jun PF03957.13 KEZ45347.1 - 0.03 14.2 1.0 0.052 13.4 1.0 1.3 1 0 0 1 1 1 0 Jun-like transcription factor SpoIIP PF07454.11 KEZ45348.1 - 0.055 12.9 8.9 0.024 14.1 3.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) S1 PF00575.23 KEZ45349.1 - 1.3e-82 272.2 29.9 1.6e-16 60.4 0.2 12.8 12 0 0 12 12 12 11 S1 RNA binding domain TPR_14 PF13428.6 KEZ45349.1 - 3.1e-07 30.6 0.0 0.12 13.3 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 KEZ45349.1 - 7.7e-06 25.8 2.3 0.13 12.2 0.1 5.9 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_19 PF14559.6 KEZ45349.1 - 2.2e-05 24.9 0.0 1.7 9.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat PCB_OB PF17092.5 KEZ45349.1 - 0.00022 21.9 3.2 0.19 12.5 0.0 6.3 6 2 2 8 8 6 1 Penicillin-binding protein OB-like domain EF-hand_4 PF12763.7 KEZ45349.1 - 0.0003 20.7 0.0 0.00081 19.3 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand TPR_16 PF13432.6 KEZ45349.1 - 0.0028 18.2 0.6 0.26 12.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.20 KEZ45349.1 - 0.0039 17.3 0.3 0.024 14.9 0.0 2.4 2 0 0 2 2 2 1 PPR repeat S1_2 PF13509.6 KEZ45349.1 - 0.02 14.9 0.2 30 4.8 0.0 4.9 6 0 0 6 6 6 0 S1 domain NRDE-2 PF08424.10 KEZ45349.1 - 0.045 12.9 3.5 0.093 11.8 0.8 2.6 2 2 0 2 2 2 0 NRDE-2, necessary for RNA interference PPR_2 PF13041.6 KEZ45349.1 - 0.21 11.8 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family Amastin PF07344.11 KEZ45350.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.0 2 1 1 3 3 3 0 Amastin surface glycoprotein ABC2_membrane PF01061.24 KEZ45350.1 - 2 7.8 16.4 0.03 13.7 3.9 2.3 2 1 0 2 2 2 0 ABC-2 type transporter NapE PF06796.11 KEZ45350.1 - 6.7 6.3 6.7 8.4 6.0 0.4 2.7 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Methyltransf_31 PF13847.6 KEZ45351.1 - 4.7e-21 75.2 0.0 7.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45351.1 - 2e-14 54.1 0.0 4.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45351.1 - 1.1e-12 48.4 0.0 2.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45351.1 - 3.2e-10 39.8 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEZ45351.1 - 2.2e-08 34.1 0.0 3.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KEZ45351.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 KEZ45351.1 - 0.0014 18.4 0.1 0.0071 16.1 0.1 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KEZ45351.1 - 0.0016 19.2 0.0 0.0033 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEZ45351.1 - 0.0034 16.8 0.7 0.0063 15.9 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 KEZ45351.1 - 0.0053 16.6 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase DOT1 PF08123.13 KEZ45351.1 - 0.039 13.5 0.6 0.41 10.1 0.6 2.2 1 1 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.20 KEZ45351.1 - 0.073 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase bZIP_2 PF07716.15 KEZ45352.1 - 3.5e-05 23.8 4.6 5.9e-05 23.1 4.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KEZ45352.1 - 0.00027 21.0 6.8 0.00055 20.0 6.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF3584 PF12128.8 KEZ45352.1 - 0.00067 17.3 2.0 0.00094 16.8 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DivIC PF04977.15 KEZ45352.1 - 0.013 15.3 1.2 0.028 14.2 1.2 1.5 1 0 0 1 1 1 0 Septum formation initiator CCDC144C PF14915.6 KEZ45352.1 - 0.026 13.7 1.9 0.044 12.9 1.9 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TMF_DNA_bd PF12329.8 KEZ45352.1 - 0.037 14.0 0.8 0.066 13.2 0.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CREPT PF16566.5 KEZ45352.1 - 0.071 13.3 2.1 0.15 12.2 2.1 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour ZapB PF06005.12 KEZ45352.1 - 0.09 13.2 0.2 0.24 11.9 0.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB BLOC1_2 PF10046.9 KEZ45352.1 - 0.11 12.8 0.3 0.22 11.9 0.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4094 PF13334.6 KEZ45352.1 - 0.12 12.8 0.3 0.3 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) FapA PF03961.13 KEZ45352.1 - 0.13 10.8 0.4 1.1 7.8 0.6 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A LPP PF04728.13 KEZ45352.1 - 0.15 12.5 0.7 0.38 11.2 0.7 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TMPIT PF07851.13 KEZ45352.1 - 0.19 10.9 0.7 0.3 10.3 0.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Nop25 PF09805.9 KEZ45352.1 - 0.19 12.2 3.9 0.32 11.5 3.9 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CASP_C PF08172.12 KEZ45352.1 - 0.22 10.8 3.9 0.39 10.0 3.9 1.3 1 0 0 1 1 1 0 CASP C terminal Herpes_UL25 PF01499.16 KEZ45352.1 - 0.24 9.9 3.3 0.35 9.3 3.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Uds1 PF15456.6 KEZ45352.1 - 1.5 9.0 5.8 1.2 9.3 3.6 1.8 2 0 0 2 2 2 0 Up-regulated During Septation PT-VENN PF04829.13 KEZ45353.1 - 1.1 9.4 5.5 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif RRM_1 PF00076.22 KEZ45354.1 - 1.7e-15 56.6 0.0 3.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.11 KEZ45354.1 - 3.3 7.7 15.9 5.8 6.9 15.9 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.9 KEZ45354.1 - 5.9 5.6 26.4 7.9 5.2 26.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Usp PF00582.26 KEZ45355.1 - 1.9e-13 51.1 0.0 5.2e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Universal stress protein family Paf67 PF10255.9 KEZ45356.1 - 5.9e-154 512.9 0.6 7.3e-154 512.6 0.6 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KEZ45356.1 - 0.047 13.8 0.7 0.16 12.2 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KEZ45356.1 - 1 9.8 4.6 21 5.6 0.8 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 KEZ45357.1 - 2.8e-59 200.0 0.0 7.1e-59 198.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KEZ45357.1 - 1.8e-15 56.8 0.0 5e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KEZ45357.1 - 4.5e-12 46.2 0.0 1.8e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KEZ45357.1 - 7e-09 35.7 0.0 1.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KEZ45357.1 - 2.3e-05 24.2 0.0 0.00024 20.8 0.0 2.6 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KEZ45357.1 - 0.05 13.7 0.0 0.17 11.9 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pol_alpha_B_N PF08418.10 KEZ45357.1 - 0.13 12.2 0.5 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal zf-MYND PF01753.18 KEZ45358.1 - 0.00037 20.5 11.8 0.00037 20.5 11.8 2.5 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KEZ45358.1 - 2 8.8 8.1 12 6.3 7.2 2.5 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding JAB PF01398.21 KEZ45359.1 - 3.6e-31 107.6 0.1 5.1e-31 107.1 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KEZ45359.1 - 1.3e-19 70.9 0.1 2.6e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KEZ45359.1 - 3.6e-05 23.5 0.0 7.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain His_Phos_1 PF00300.22 KEZ45360.1 - 1.2e-10 41.4 2.3 3.5e-10 39.9 1.2 2.2 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Gln_amidase PF15644.6 KEZ45360.1 - 0.081 13.9 0.1 0.17 12.9 0.1 1.5 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase APC_r PF05923.12 KEZ45360.1 - 0.098 12.4 0.0 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 APC repeat Cullin PF00888.22 KEZ45361.1 - 8.7e-168 559.7 0.8 1.1e-167 559.4 0.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KEZ45361.1 - 3.9e-24 84.5 0.7 1.1e-23 83.0 0.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Ca_bind_SSO6904 PF18249.1 KEZ45361.1 - 0.074 13.4 0.5 1.5 9.2 0.1 2.7 2 1 0 2 2 2 0 Calcium binding protein SSO6904 GatB_Yqey PF02637.18 KEZ45361.1 - 0.35 10.7 2.4 1.4 8.8 1.3 2.4 2 0 0 2 2 2 0 GatB domain PI3_PI4_kinase PF00454.27 KEZ45362.1 - 2.9e-48 164.9 0.0 6.7e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KEZ45362.1 - 1.3e-34 119.5 0.0 8.6e-34 116.8 0.0 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KEZ45362.1 - 1.5e-11 43.9 0.0 4.1e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 KEZ45362.1 - 2.6e-10 40.1 6.8 5.3e-10 39.0 6.8 1.5 1 0 0 1 1 1 1 FAT domain Nup192 PF11894.8 KEZ45363.1 - 0 1436.3 0.0 0 1436.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Dicty_CAD PF05720.12 KEZ45363.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Cell-cell adhesion domain DNApol_Exo PF18136.1 KEZ45364.1 - 2.7e-104 348.3 0.0 4.3e-104 347.6 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KEZ45364.1 - 3e-58 197.7 0.0 4.8e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A COesterase PF00135.28 KEZ45365.1 - 3.9e-82 276.8 0.0 2.2e-81 274.3 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ45365.1 - 3.4e-12 46.7 0.1 1.6e-11 44.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hce2 PF14856.6 KEZ45365.1 - 4.2e-07 30.2 0.0 1.6e-06 28.4 0.0 2.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Peptidase_S9 PF00326.21 KEZ45365.1 - 0.043 13.3 0.2 0.078 12.4 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lectin_C PF00059.21 KEZ45365.1 - 0.07 13.9 0.4 0.63 10.8 0.5 2.3 1 1 1 2 2 2 0 Lectin C-type domain PIF1 PF05970.14 KEZ45366.1 - 1.6e-58 198.6 0.3 2e-55 188.5 0.3 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KEZ45366.1 - 7.6e-24 84.5 0.0 1.5e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KEZ45366.1 - 8.2e-11 42.4 0.0 3e-10 40.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain Helo_like_N PF17111.5 KEZ45366.1 - 3.5e-09 36.4 0.7 6.8e-09 35.4 0.7 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KEZ45366.1 - 2.4e-05 24.6 0.1 0.00013 22.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEZ45366.1 - 4.8e-05 22.9 0.0 9.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 KEZ45366.1 - 0.00027 21.4 1.3 0.00078 19.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KEZ45366.1 - 0.0013 19.2 0.0 0.0038 17.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KEZ45366.1 - 0.0014 18.4 0.1 0.0034 17.2 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KEZ45366.1 - 0.0015 18.0 0.0 0.0042 16.6 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein TPR_12 PF13424.6 KEZ45366.1 - 0.0022 18.2 2.7 0.05 13.9 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat Herpes_Helicase PF02689.14 KEZ45366.1 - 0.0024 15.9 0.0 0.0053 14.7 0.0 1.4 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 KEZ45366.1 - 0.0044 16.1 0.0 0.0097 15.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 KEZ45366.1 - 0.015 15.8 0.0 0.063 13.8 0.0 2.1 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KEZ45366.1 - 0.019 14.2 0.1 0.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SH3_13 PF18335.1 KEZ45366.1 - 0.022 14.6 0.2 0.058 13.2 0.2 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain RNA_helicase PF00910.22 KEZ45366.1 - 0.022 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 KEZ45366.1 - 0.025 14.4 0.0 0.072 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KEZ45366.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 KEZ45366.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KEZ45366.1 - 0.045 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 KEZ45366.1 - 0.07 12.9 0.1 4.5 7.0 0.0 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KEZ45366.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KEZ45366.1 - 0.094 12.5 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 KEZ45366.1 - 0.098 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KEZ45366.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 KEZ45366.1 - 0.13 12.4 0.1 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain YjeF_N PF03853.15 KEZ45367.1 - 3.2e-40 137.8 0.0 4.8e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KEZ45367.1 - 5.8e-08 33.5 0.8 5.8e-08 33.5 0.8 1.9 2 0 0 2 2 2 1 FDF domain Peptidase_C15 PF01470.17 KEZ45370.1 - 2e-11 44.4 0.0 1.3e-10 41.8 0.0 1.9 1 1 0 1 1 1 1 Pyroglutamyl peptidase PhoD PF09423.10 KEZ45371.1 - 9.5e-109 363.6 1.1 1.3e-108 363.2 1.1 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KEZ45371.1 - 1.3e-30 105.7 0.2 2.5e-30 104.9 0.2 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KEZ45371.1 - 0.00041 20.9 0.2 0.00097 19.7 0.2 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Aldo_ket_red PF00248.21 KEZ45373.1 - 1.2e-27 96.9 0.0 4.7e-17 62.1 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family DUF1996 PF09362.10 KEZ45374.1 - 1.5e-82 277.1 0.6 1.8e-82 276.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FAD_binding_3 PF01494.19 KEZ45376.1 - 1.6e-12 47.4 0.1 8.6e-07 28.5 0.0 2.7 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 KEZ45376.1 - 5.9e-09 36.0 0.3 0.00021 21.0 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ45376.1 - 5.2e-08 32.5 0.0 0.0032 16.7 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ45376.1 - 0.00011 21.4 0.0 0.00023 20.3 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ45376.1 - 0.0018 18.5 0.1 0.017 15.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KEZ45376.1 - 0.0032 16.4 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 KEZ45376.1 - 0.0043 16.2 0.0 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 KEZ45376.1 - 0.024 13.7 0.0 0.15 11.1 0.0 1.9 1 1 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 KEZ45376.1 - 0.089 11.9 0.0 0.18 10.9 0.0 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_4 PF01565.23 KEZ45377.1 - 2.1e-23 82.6 0.2 3.1e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.13 KEZ45378.1 - 1.6e-10 41.0 0.0 5.6e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ45378.1 - 6.6e-09 35.9 0.0 1.5e-08 34.8 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KEZ45378.1 - 2.8e-05 24.4 0.0 0.00034 20.9 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DUF3871 PF12987.7 KEZ45378.1 - 0.21 10.4 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) p450 PF00067.22 KEZ45379.1 - 3.6e-78 263.4 0.0 1.4e-76 258.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEZ45380.1 - 2.3e-62 211.3 0.0 2.9e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 KEZ45381.1 - 1.1e-129 433.0 0.4 1.5e-129 432.5 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KEZ45381.1 - 0.00026 20.5 0.1 0.00047 19.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) DLH PF01738.18 KEZ45382.1 - 8.8e-09 35.2 0.0 6e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family adh_short PF00106.25 KEZ45382.1 - 0.0013 18.2 0.2 0.003 17.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Abhydrolase_6 PF12697.7 KEZ45382.1 - 0.028 15.0 0.0 0.076 13.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 KEZ45382.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FAD_binding_4 PF01565.23 KEZ45383.1 - 4e-26 91.4 0.0 8.7e-26 90.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ45383.1 - 2.4e-06 27.4 0.0 3.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 KEZ45384.1 - 1.6e-07 32.2 0.0 3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Beta-lactamase PF00144.24 KEZ45385.1 - 3.1e-45 154.9 0.1 2.2e-44 152.0 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 KEZ45386.1 - 1.4e-16 60.1 0.4 2.1e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KEZ45386.1 - 6.6e-13 48.5 0.0 6.1e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ45386.1 - 2.8e-10 39.9 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ45386.1 - 3.8e-09 36.1 0.0 1.1e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KEZ45386.1 - 8.2e-06 26.0 0.2 5.5e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ45386.1 - 0.036 13.1 0.0 0.11 11.5 0.0 1.9 1 0 0 1 1 1 0 Lycopene cyclase protein Zn_clus PF00172.18 KEZ45386.1 - 0.067 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_9 PF13454.6 KEZ45386.1 - 0.07 13.1 1.4 27 4.7 0.0 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 KEZ45386.1 - 0.15 11.6 0.1 3 7.3 0.0 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ45388.1 - 6.3e-13 48.7 0.0 2.1e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ45388.1 - 0.0016 18.1 0.2 0.0036 16.9 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ45388.1 - 0.0053 17.0 0.1 0.016 15.4 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ45388.1 - 0.0097 15.2 0.0 0.11 11.7 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ45388.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ45388.1 - 0.023 15.3 0.7 0.049 14.2 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_10 PF13374.6 KEZ45389.1 - 1.4e-58 193.3 19.6 2.6e-09 36.6 0.0 11.0 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ45389.1 - 1e-56 189.1 6.0 5.1e-15 55.5 0.1 8.7 4 3 5 9 9 9 9 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ45389.1 - 3e-12 46.6 4.6 5.5e-06 26.0 0.3 3.3 1 1 3 4 4 4 2 MalT-like TPR region TPR_2 PF07719.17 KEZ45389.1 - 2.4e-11 42.8 2.5 0.043 13.9 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ45389.1 - 6.9e-11 41.4 3.0 0.13 12.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ45389.1 - 9.6e-11 41.6 4.8 0.2 12.6 0.0 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ45389.1 - 2.6e-09 36.6 1.8 0.29 11.5 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ45389.1 - 2.7e-09 37.5 1.1 0.00011 22.7 0.0 4.6 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ45389.1 - 3.6e-09 36.1 1.8 0.13 12.2 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Clr5 PF14420.6 KEZ45389.1 - 1.4e-08 34.8 0.2 4.6e-08 33.2 0.2 2.0 1 0 0 1 1 1 1 Clr5 domain TPR_4 PF07721.14 KEZ45389.1 - 1e-06 28.8 10.0 0.83 10.5 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_5 PF12688.7 KEZ45389.1 - 0.00011 22.4 5.2 1.4 9.2 0.1 4.1 3 2 1 4 4 4 2 Tetratrico peptide repeat TPR_19 PF14559.6 KEZ45389.1 - 0.00034 21.1 5.6 0.63 10.6 0.2 4.1 2 2 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ45389.1 - 0.0006 20.0 0.0 2.2 8.6 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KEZ45389.1 - 0.00079 19.6 1.0 6.2 7.5 0.1 4.8 5 0 0 5 5 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 KEZ45389.1 - 0.0015 18.6 3.0 2.9 8.0 0.2 3.3 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) DUF4477 PF14780.6 KEZ45389.1 - 0.0082 15.8 0.6 2.7 7.6 0.1 3.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4477) STAT_int PF02865.17 KEZ45389.1 - 0.031 14.7 0.2 1 9.8 0.0 3.0 3 0 0 3 3 2 0 STAT protein, protein interaction domain DUF4145 PF13643.6 KEZ45389.1 - 0.052 13.7 0.6 2.3 8.4 0.1 3.5 3 1 1 4 4 3 0 Domain of unknown function (DUF4145) TPR_20 PF14561.6 KEZ45389.1 - 0.27 11.6 4.6 1e+02 3.3 0.1 5.3 4 3 1 6 6 6 0 Tetratricopeptide repeat TBCA PF02970.16 KEZ45389.1 - 0.36 11.2 2.0 2.7 8.4 0.2 3.2 2 1 1 3 3 3 0 Tubulin binding cofactor A TPR_6 PF13174.6 KEZ45389.1 - 0.45 11.3 7.0 11 6.9 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4404 PF14357.6 KEZ45389.1 - 1.1 9.9 5.2 2.9 8.6 0.2 3.7 3 1 1 4 4 3 0 Domain of unknown function (DUF4404) Patched PF02460.18 KEZ45391.1 - 0.05 11.7 0.8 1 7.4 0.1 2.0 2 0 0 2 2 2 0 Patched family FMN_dh PF01070.18 KEZ45392.1 - 1.1e-72 245.0 0.1 5e-72 242.8 0.1 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KEZ45392.1 - 1.1e-05 24.9 0.2 0.058 12.6 0.0 2.3 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase IMPDH PF00478.25 KEZ45392.1 - 0.01 14.9 0.3 0.032 13.2 0.3 1.8 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KEZ45392.1 - 0.041 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 KEZ45392.1 - 0.13 11.7 0.5 20 4.5 0.1 2.9 2 1 1 3 3 3 0 Histidine biosynthesis protein ADH_N PF08240.12 KEZ45393.1 - 1.4e-06 28.2 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KEZ45393.1 - 0.045 13.7 0.0 0.09 12.7 0.0 1.5 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase TCTP PF00838.17 KEZ45394.1 - 4.3e-71 238.6 2.2 4.9e-71 238.4 2.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Prp18 PF02840.15 KEZ45397.1 - 1.6e-52 177.4 0.0 1.6e-52 177.4 0.0 2.0 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KEZ45397.1 - 3.3e-10 39.3 1.8 3.3e-10 39.3 1.8 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC45 PF02724.14 KEZ45397.1 - 0.72 8.1 13.4 0.86 7.8 13.4 1.3 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 KEZ45397.1 - 1.8 7.9 21.7 3.4 7.0 21.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 V_ATPase_I PF01496.19 KEZ45397.1 - 2.5 5.9 5.9 3.7 5.4 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 KEZ45397.1 - 5.9 5.5 10.3 8.7 5.0 10.3 1.2 1 0 0 1 1 1 0 Presenilin GST_N PF02798.20 KEZ45398.1 - 1.5e-08 34.9 0.0 1.4e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KEZ45398.1 - 2.1e-07 31.1 0.1 5.7e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ45398.1 - 2.5e-07 30.6 0.1 4.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KEZ45398.1 - 3.4e-07 30.6 0.0 7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KEZ45398.1 - 4.7e-05 23.5 0.0 8.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KEZ45398.1 - 0.00016 21.8 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WAC_Acf1_DNA_bd PF10537.9 KEZ45399.1 - 1.4e-38 131.5 2.3 1.4e-38 131.5 0.1 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KEZ45399.1 - 9.2e-19 67.8 0.1 5.7e-18 65.2 0.1 2.5 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KEZ45399.1 - 1.1e-16 60.8 0.5 2.1e-16 60.0 0.5 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KEZ45399.1 - 4.4e-06 26.1 0.3 0.00011 21.6 0.0 2.8 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 PDDEXK_9 PF08011.11 KEZ45400.1 - 0.00015 21.6 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily HSDR_N_2 PF13588.6 KEZ45400.1 - 0.037 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) CorA PF01544.18 KEZ45401.1 - 2.6e-12 46.7 1.1 5.1e-12 45.7 1.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3169 PF11368.8 KEZ45401.1 - 0.1 12.1 0.7 0.16 11.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) RepA_N PF06970.11 KEZ45401.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus DUF1270 PF06900.11 KEZ45401.1 - 1 9.8 3.6 3.4 8.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) PH_14 PF17787.1 KEZ45402.1 - 0.026 14.4 0.0 0.069 13.0 0.0 1.7 1 1 0 1 1 1 0 PH domain Alg6_Alg8 PF03155.15 KEZ45404.1 - 1.8e-156 521.9 25.9 2.3e-156 521.6 25.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ATP1G1_PLM_MAT8 PF02038.16 KEZ45404.1 - 2 7.9 4.8 2.2 7.8 0.2 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Lectin_leg-like PF03388.13 KEZ45405.1 - 4e-23 81.9 0.0 7.5e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Legume-like lectin family DUF2353 PF09789.9 KEZ45405.1 - 0.0003 20.3 1.3 0.00059 19.3 1.3 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Lectin_N PF03954.14 KEZ45405.1 - 0.0016 18.2 1.1 0.24 11.2 0.2 2.3 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain DUF812 PF05667.11 KEZ45405.1 - 0.024 13.6 0.5 0.032 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 KEZ45405.1 - 0.029 14.4 2.5 0.21 11.6 0.9 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 KEZ45405.1 - 0.04 14.5 0.8 0.099 13.2 0.8 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ATF7IP_BD PF16788.5 KEZ45405.1 - 0.063 13.4 0.3 0.063 13.4 0.3 1.8 2 1 0 2 2 2 0 ATF-interacting protein binding domain TMF_TATA_bd PF12325.8 KEZ45405.1 - 0.081 13.1 1.1 0.2 11.9 1.1 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 KEZ45405.1 - 0.11 13.0 0.1 0.11 13.0 0.1 1.4 2 0 0 2 2 1 0 Fez1 FUSC PF04632.12 KEZ45405.1 - 0.21 10.1 1.0 0.29 9.6 1.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KEZ45405.1 - 0.22 11.6 1.9 0.53 10.3 1.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 KEZ45405.1 - 0.34 11.0 4.6 8.4 6.6 0.0 2.7 2 1 0 3 3 3 0 TolA binding protein trimerisation SlyX PF04102.12 KEZ45405.1 - 0.35 11.5 2.7 15 6.3 0.4 2.4 1 1 1 2 2 2 0 SlyX FAM76 PF16046.5 KEZ45405.1 - 0.43 9.9 4.8 0.73 9.1 4.8 1.3 1 0 0 1 1 1 0 FAM76 protein DUF948 PF06103.11 KEZ45405.1 - 1 9.6 3.4 3.2 8.1 1.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 KEZ45405.1 - 4.3 7.7 7.2 0.42 11.0 0.4 2.5 3 1 1 4 4 3 0 Outer membrane protein (OmpH-like) Peptidase_M24 PF00557.24 KEZ45406.1 - 1.9e-63 214.0 0.1 2.8e-63 213.4 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEZ45406.1 - 5.4e-22 77.8 0.0 1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.18 KEZ45406.1 - 4.8e-08 33.0 10.3 1e-07 32.0 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 KEZ45407.1 - 8.2e-105 350.4 35.3 1.4e-52 179.1 12.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KEZ45407.1 - 7.9e-68 227.2 0.0 1.6e-33 116.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KEZ45407.1 - 6.1e-14 52.0 0.0 9.1e-05 22.0 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ45407.1 - 3.2e-07 30.0 1.7 0.0023 17.6 0.5 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ45407.1 - 8.9e-07 29.4 6.4 0.0014 19.0 0.1 3.2 3 1 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ45407.1 - 6.2e-06 26.2 0.0 0.33 10.8 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase ABC_ATPase PF09818.9 KEZ45407.1 - 1.1e-05 24.5 2.7 0.093 11.5 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 KEZ45407.1 - 7.9e-05 23.0 1.8 0.44 10.8 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KEZ45407.1 - 8.8e-05 22.2 0.0 0.14 11.7 0.1 3.0 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KEZ45407.1 - 0.0004 19.7 0.0 0.18 11.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 KEZ45407.1 - 0.00043 20.1 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KEZ45407.1 - 0.0018 18.7 2.9 14 6.1 0.0 4.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 KEZ45407.1 - 0.0019 18.4 2.2 1.7 8.9 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KEZ45407.1 - 0.0019 18.3 0.3 2 8.5 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_5 PF07728.14 KEZ45407.1 - 0.0075 16.3 0.2 4.6 7.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEZ45407.1 - 0.0077 16.4 0.0 7.1 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEZ45407.1 - 0.0082 16.4 0.9 0.55 10.5 0.1 2.6 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KEZ45407.1 - 0.0083 15.3 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KEZ45407.1 - 0.011 15.6 1.0 5.8 6.6 0.0 3.7 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KEZ45407.1 - 0.012 15.4 3.2 3.4 7.4 0.1 3.5 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 KEZ45407.1 - 0.036 13.6 0.0 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KEZ45407.1 - 0.043 14.4 0.1 17 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KEZ45407.1 - 0.05 12.8 0.1 4.4 6.4 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KEZ45407.1 - 0.08 12.9 0.0 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 KEZ45407.1 - 0.13 12.7 2.2 4.2 7.8 0.1 3.1 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 KEZ45407.1 - 0.15 11.4 0.2 10 5.4 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KEZ45407.1 - 0.2 12.1 0.1 11 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Sporozoite_P67 PF05642.11 KEZ45408.1 - 0.0045 15.2 2.1 0.0058 14.8 2.1 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Fungal_trans PF04082.18 KEZ45409.1 - 1.6e-27 96.2 0.1 2.4e-27 95.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPN7 PF10602.9 KEZ45410.1 - 6.5e-41 139.9 0.3 1.4e-40 138.8 0.0 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KEZ45410.1 - 2.3e-14 53.8 0.1 3.2e-12 46.9 0.0 2.4 2 0 0 2 2 2 1 PCI domain DUF1299 PF06975.11 KEZ45410.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) ANAPC3 PF12895.7 KEZ45410.1 - 0.28 11.4 8.2 0.26 11.6 0.3 3.8 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KEZ45410.1 - 1.8 8.9 4.6 14 6.1 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BRE1 PF08647.11 KEZ45411.1 - 4.3e-24 84.4 9.6 4.3e-24 84.4 9.6 6.7 4 2 3 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KEZ45411.1 - 3.7e-09 36.3 8.9 6.1e-09 35.6 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ45411.1 - 6.2e-09 35.6 12.3 1.1e-08 34.8 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ45411.1 - 2.5e-08 33.6 7.4 4.2e-08 32.9 7.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KEZ45411.1 - 7.7e-08 32.1 9.0 1.3e-07 31.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ45411.1 - 1e-06 28.6 11.0 1.7e-06 27.9 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEZ45411.1 - 1.2e-06 28.4 8.8 2.3e-06 27.5 8.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KEZ45411.1 - 6.6e-06 26.4 9.3 1.1e-05 25.7 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain VGPC1_C PF16799.5 KEZ45411.1 - 0.0027 17.6 9.9 0.075 13.0 0.4 4.3 4 0 0 4 4 4 1 C-terminal membrane-localisation domain of ion-channel, VCN1 bZIP_2 PF07716.15 KEZ45411.1 - 0.0089 16.1 2.8 0.0089 16.1 2.8 8.0 8 2 2 10 10 9 2 Basic region leucine zipper DivIC PF04977.15 KEZ45411.1 - 0.014 15.1 3.9 0.014 15.1 3.9 7.9 5 2 3 8 8 8 0 Septum formation initiator zf-C2HC_2 PF13913.6 KEZ45411.1 - 0.017 15.1 0.2 0.91 9.5 0.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C3HC4_4 PF15227.6 KEZ45411.1 - 0.023 14.9 7.8 0.046 13.9 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KEZ45411.1 - 0.067 13.1 3.0 0.13 12.1 3.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1192 PF06698.11 KEZ45411.1 - 0.073 13.1 0.5 0.073 13.1 0.5 4.5 6 0 0 6 6 4 0 Protein of unknown function (DUF1192) zf-UDP PF14569.6 KEZ45411.1 - 0.18 12.0 4.5 0.57 10.3 4.5 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-rbx1 PF12678.7 KEZ45411.1 - 0.23 11.8 8.1 0.7 10.2 8.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KEZ45411.1 - 0.4 10.5 4.8 1 9.2 4.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 KEZ45411.1 - 0.46 10.3 7.4 0.93 9.3 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 KEZ45411.1 - 0.62 10.3 12.0 4 7.6 11.5 2.3 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.8 KEZ45411.1 - 0.76 9.6 5.1 1.6 8.6 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_jaz PF12171.8 KEZ45411.1 - 1.2 9.5 4.4 90 3.5 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SHE3 PF17078.5 KEZ45411.1 - 5.5 6.6 54.5 0.029 14.1 11.1 4.7 1 1 3 4 4 3 0 SWI5-dependent HO expression protein 3 zf-C2H2_4 PF13894.6 KEZ45411.1 - 7.6 7.7 7.1 71 4.7 0.4 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger XPC-binding PF09280.11 KEZ45412.1 - 2.5e-25 88.0 10.5 4.1e-25 87.3 10.5 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KEZ45412.1 - 5.2e-22 77.4 0.5 8.6e-22 76.7 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KEZ45412.1 - 2.7e-21 75.1 8.0 3e-11 43.0 0.8 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 KEZ45412.1 - 2.4e-08 33.7 0.9 3.7e-08 33.1 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KEZ45412.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KEZ45412.1 - 0.018 15.6 0.0 0.035 14.7 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 KEZ45412.1 - 0.025 15.0 0.3 0.041 14.2 0.3 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain WIYLD PF10440.9 KEZ45412.1 - 0.049 13.4 0.3 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain UBA_3 PF09288.10 KEZ45412.1 - 0.12 12.1 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain NUDE_C PF04880.13 KEZ45412.1 - 2.5 8.6 4.9 4.5 7.7 4.9 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TFIIA PF03153.13 KEZ45412.1 - 2.9 7.8 8.3 4.1 7.3 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltr_RsmB-F PF01189.17 KEZ45413.1 - 4.3e-17 62.4 0.0 1.3e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Nop14 PF04147.12 KEZ45413.1 - 2 6.5 12.4 3 5.9 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family BicD PF09730.9 KEZ45414.1 - 0.025 13.0 0.0 0.03 12.8 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D V_ATPase_I PF01496.19 KEZ45415.1 - 0.0013 16.8 9.6 0.0085 14.1 0.0 2.0 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family FapA PF03961.13 KEZ45415.1 - 0.024 13.3 9.1 0.44 9.1 2.7 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A ATF7IP_BD PF16788.5 KEZ45415.1 - 0.63 10.1 18.7 1.5 8.9 12.1 2.4 2 0 0 2 2 2 0 ATF-interacting protein binding domain KxDL PF10241.9 KEZ45415.1 - 1.9 8.8 6.6 14 6.0 0.3 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein Fez1 PF06818.15 KEZ45415.1 - 5.3 7.4 16.2 0.37 11.2 2.1 2.2 2 0 0 2 2 2 0 Fez1 SlyX PF04102.12 KEZ45415.1 - 8.3 7.1 7.0 11 6.7 1.1 3.5 2 2 1 3 3 3 0 SlyX PALP PF00291.25 KEZ45416.1 - 2.8e-66 223.9 0.1 3.6e-66 223.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KEZ45416.1 - 1e-10 41.9 0.2 7.9e-08 32.6 0.0 3.4 4 0 0 4 4 4 2 CBS domain Ank_2 PF12796.7 KEZ45417.1 - 3.3e-26 91.7 0.0 1.6e-13 51.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ45417.1 - 1e-23 83.0 0.0 1.7e-06 28.2 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ45417.1 - 1.1e-22 80.1 0.9 1.5e-07 31.9 0.2 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KEZ45417.1 - 7.1e-21 73.7 0.0 2.3e-05 24.6 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KEZ45417.1 - 9.2e-21 71.7 0.4 7.1e-07 29.1 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat DHHC PF01529.20 KEZ45417.1 - 2.8e-10 40.4 21.2 2.8e-10 40.4 21.2 3.5 3 1 0 3 3 3 1 DHHC palmitoyltransferase TPP_enzyme_N PF02776.18 KEZ45418.1 - 3.8e-38 130.8 0.0 7.9e-37 126.5 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEZ45418.1 - 7.7e-23 81.0 0.1 1.3e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ45418.1 - 3.8e-12 46.1 0.0 5.7e-11 42.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_4 PF01565.23 KEZ45419.1 - 9.5e-25 87.0 4.7 1.7e-24 86.2 4.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ45419.1 - 5.6e-09 36.0 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 KEZ45419.1 - 0.0021 17.8 0.1 0.013 15.2 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase PH_10 PF15411.6 KEZ45420.1 - 1.8e-29 102.5 1.0 2.9e-29 101.8 1.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KEZ45420.1 - 4.1e-14 53.2 0.0 6.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KEZ45420.1 - 1.2e-09 38.3 0.8 6.6e-09 35.9 0.1 2.6 3 1 0 3 3 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KEZ45420.1 - 0.0001 22.6 5.4 0.00017 21.8 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KEZ45420.1 - 0.00035 20.5 5.4 0.0006 19.7 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KEZ45420.1 - 0.0024 18.1 2.6 0.0052 17.0 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KEZ45420.1 - 0.007 16.2 2.6 0.013 15.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KEZ45420.1 - 0.0097 15.5 2.3 0.0097 15.5 2.3 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PH PF00169.29 KEZ45420.1 - 0.015 15.8 0.1 0.035 14.6 0.1 1.5 1 0 0 1 1 1 0 PH domain zf-C3HC4 PF00097.25 KEZ45420.1 - 0.024 14.5 5.0 0.044 13.7 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ45420.1 - 0.038 13.9 4.4 0.071 13.0 4.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEZ45420.1 - 0.066 13.3 0.8 0.12 12.5 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 KEZ45420.1 - 0.14 12.5 3.7 0.26 11.6 3.7 1.4 1 0 0 1 1 1 0 RING-like domain DUF1147 PF06615.11 KEZ45420.1 - 0.16 12.0 0.5 0.38 10.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING_11 PF17123.5 KEZ45420.1 - 0.18 11.6 4.0 0.37 10.6 4.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 KEZ45420.1 - 0.22 11.4 4.0 0.41 10.5 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KEZ45420.1 - 0.31 11.1 2.8 0.68 10.0 2.8 1.6 1 1 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 KEZ45420.1 - 5.6 7.1 5.0 17 5.5 5.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger U3_snoRNA_assoc PF08297.11 KEZ45421.1 - 6.5e-11 42.8 3.0 6.5e-11 42.8 3.0 4.3 3 1 0 3 3 3 1 U3 snoRNA associated GREB1 PF15782.5 KEZ45421.1 - 2.6 5.0 17.4 3.5 4.6 17.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Beta-lactamase PF00144.24 KEZ45422.1 - 3.7e-29 102.0 0.2 7.3e-29 101.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase Dynamin_N PF00350.23 KEZ45423.1 - 4.7e-32 111.4 0.0 8.8e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KEZ45423.1 - 1.3e-23 83.7 2.0 5.8e-21 75.0 0.0 3.1 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.23 KEZ45423.1 - 9.6e-06 25.7 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GED PF02212.18 KEZ45423.1 - 2.5e-05 24.4 0.5 6e-05 23.1 0.5 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_15 PF13175.6 KEZ45423.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 KEZ45423.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 KEZ45423.1 - 0.047 13.2 0.0 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Med9 PF07544.13 KEZ45423.1 - 0.049 13.7 1.4 7.2 6.8 0.2 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_29 PF13555.6 KEZ45423.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ45423.1 - 0.13 12.7 0.1 0.61 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Nucleoporin_FG PF13634.6 KEZ45423.1 - 0.28 12.1 20.2 1.5 9.7 20.2 2.2 1 1 0 1 1 1 0 Nucleoporin FG repeat region DUF1996 PF09362.10 KEZ45424.1 - 7.1e-63 212.7 0.1 9.9e-63 212.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Matrilin_ccoil PF10393.9 KEZ45424.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TSP_3 PF02412.18 KEZ45424.1 - 0.16 11.7 0.6 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 Thrombospondin type 3 repeat tRNA-synt_1d PF00750.19 KEZ45425.1 - 1.1e-97 327.1 2.6 1.6e-97 326.6 2.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KEZ45425.1 - 1.9e-28 99.0 0.0 4.9e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KEZ45425.1 - 1.3e-07 32.1 0.0 6.5e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Ank_2 PF12796.7 KEZ45426.1 - 6.6e-56 186.9 0.4 8.2e-18 64.8 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ45426.1 - 3.6e-37 125.2 0.1 2.9e-06 27.5 0.0 8.2 9 0 0 9 9 8 5 Ankyrin repeat Ank_3 PF13606.6 KEZ45426.1 - 6.1e-32 106.1 0.4 0.00046 20.4 0.0 8.2 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 KEZ45426.1 - 4.1e-30 103.8 2.4 6.8e-10 39.3 0.0 6.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ45426.1 - 6.2e-26 90.1 2.5 5e-11 42.6 0.4 6.3 2 2 5 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ45426.1 - 4.9e-07 29.8 0.0 1.7e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ45426.1 - 7.1e-06 26.3 0.0 2.1e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ45426.1 - 0.002 18.5 0.0 0.0065 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain EPSP_synthase PF00275.20 KEZ45426.1 - 0.014 14.1 0.2 6.6 5.3 0.0 3.4 1 1 3 4 4 4 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) EFG_C PF00679.24 KEZ45426.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 Elongation factor G C-terminus HTH_11 PF08279.12 KEZ45426.1 - 1.5 8.8 4.9 2.9e+02 1.5 0.1 5.3 6 0 0 6 6 6 0 HTH domain Ferric_reduct PF01794.19 KEZ45427.1 - 8.1e-21 74.4 13.1 1.8e-20 73.3 13.1 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KEZ45427.1 - 3.4e-12 46.4 0.0 7.5e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KEZ45427.1 - 1.3e-10 41.6 0.0 2.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF3746 PF12562.8 KEZ45427.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) RINGv PF12906.7 KEZ45429.1 - 1.2e-16 60.6 9.1 1.9e-16 59.9 9.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KEZ45429.1 - 0.015 15.6 9.5 0.026 14.8 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KEZ45429.1 - 0.48 10.5 2.5 1.1 9.3 2.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KEZ45429.1 - 1.2 9.0 6.1 2.6 8.0 6.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fib_alpha PF08702.10 KEZ45430.1 - 0.28 11.4 1.2 0.82 9.8 1.2 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HeLo PF14479.6 KEZ45431.1 - 7.6e-07 29.2 1.2 0.0075 16.1 0.0 3.2 3 0 0 3 3 3 2 Prion-inhibition and propagation YL1 PF05764.13 KEZ45431.1 - 0.0025 18.0 7.4 0.0025 18.0 7.4 2.8 3 0 0 3 3 3 1 YL1 nuclear protein DUF4766 PF15973.5 KEZ45431.1 - 0.47 11.0 4.9 0.33 11.5 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4766) CDC45 PF02724.14 KEZ45431.1 - 2.1 6.5 12.2 1.6 6.9 3.3 2.2 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 KEZ45431.1 - 5 6.5 23.5 1.3 8.4 6.3 2.4 2 0 0 2 2 2 0 SDA1 NFACT-R_1 PF05670.13 KEZ45432.1 - 1.1e-41 141.8 0.1 1.8e-41 141.2 0.1 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain BTB PF00651.31 KEZ45433.1 - 1.2e-06 28.7 0.0 6.7e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain HAUS-augmin3 PF14932.6 KEZ45434.1 - 0.0027 17.4 0.1 0.0027 17.4 0.1 3.4 2 1 1 4 4 4 1 HAUS augmin-like complex subunit 3 Snapin_Pallidin PF14712.6 KEZ45434.1 - 0.0034 17.8 0.8 0.0034 17.8 0.8 3.8 3 2 1 5 5 5 1 Snapin/Pallidin MbeD_MobD PF04899.12 KEZ45434.1 - 0.1 12.8 2.9 30 4.8 0.7 4.2 4 0 0 4 4 4 0 MbeD/MobD like DUF5082 PF16888.5 KEZ45434.1 - 0.16 12.2 12.3 0.41 10.9 6.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Ribonuc_2-5A PF06479.12 KEZ45434.1 - 0.19 11.9 3.9 0.56 10.4 0.5 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A DASH_Dam1 PF08653.10 KEZ45434.1 - 0.27 11.0 1.2 1.1 9.1 0.1 2.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF148 PF02520.17 KEZ45434.1 - 3.5 7.8 10.0 0.57 10.3 2.6 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF148 EMP24_GP25L PF01105.24 KEZ45434.1 - 4.4 7.2 8.8 3.2 7.7 1.9 3.1 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF948 PF06103.11 KEZ45434.1 - 5.3 7.4 11.3 8.3 6.7 0.4 4.5 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) TT_ORF1 PF02956.14 KEZ45434.1 - 5.3 5.6 6.2 8.3 5.0 6.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 Prefoldin PF02996.17 KEZ45434.1 - 7.6 6.5 10.3 13 5.7 0.4 3.8 4 1 0 4 4 4 0 Prefoldin subunit LrgB PF04172.16 KEZ45435.1 - 1.5e-21 76.9 10.0 1.6e-16 60.5 1.4 2.4 2 1 0 2 2 2 2 LrgB-like family Rotamase PF00639.21 KEZ45436.1 - 5.7e-23 81.7 0.0 8.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KEZ45436.1 - 5.9e-18 65.5 0.0 8.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KEZ45436.1 - 1.2e-05 25.3 1.9 1.2e-05 25.3 1.9 2.0 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KEZ45436.1 - 2.2e-05 25.3 0.0 3.6e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L14 PF00238.19 KEZ45437.1 - 8.2e-46 155.1 4.0 9.1e-46 154.9 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.28 KEZ45438.1 - 1.2e-09 38.8 0.1 5e-09 36.8 0.1 2.0 1 1 0 1 1 1 1 SET domain Peptidase_M24 PF00557.24 KEZ45439.1 - 5.1e-56 189.7 0.0 7.2e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KEZ45439.1 - 1.7e-24 85.9 0.0 3.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain p450 PF00067.22 KEZ45440.1 - 3.3e-49 167.9 0.0 4.4e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 KEZ45441.1 - 7.8e-50 168.9 2.3 7.8e-50 168.9 2.3 2.5 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ45441.1 - 4.9e-17 62.9 1.9 1e-15 58.6 1.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KEZ45441.1 - 1.7e-07 31.6 0.0 6.1e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain SAD_SRA PF02182.17 KEZ45442.1 - 8.1e-31 106.8 0.6 1.2e-30 106.3 0.6 1.3 1 0 0 1 1 1 1 SAD/SRA domain Amidohydro_1 PF01979.20 KEZ45443.1 - 5.5e-13 48.9 0.0 7.9e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KEZ45443.1 - 6.6e-08 32.5 0.0 1.4e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family DUF2288 PF10052.9 KEZ45444.1 - 0.0062 16.6 0.2 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2288) Dpoe2NT PF12213.8 KEZ45444.1 - 0.0071 16.6 1.0 0.81 10.0 0.2 2.5 2 0 0 2 2 2 2 DNA polymerases epsilon N terminal Fe-S_biosyn PF01521.20 KEZ45445.1 - 3.5e-16 59.4 0.0 4.7e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.10 KEZ45446.1 - 2.8e-87 292.2 0.0 6.4e-87 291.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) tRNA-synt_1c PF00749.21 KEZ45447.1 - 2.3e-101 338.8 0.0 3.2e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEZ45447.1 - 4.8e-28 98.2 0.0 1.4e-27 96.7 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Bromodomain PF00439.25 KEZ45448.1 - 1.7e-30 104.9 0.0 6e-19 67.9 0.0 2.9 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KEZ45448.1 - 2.5e-07 30.8 0.2 8.8e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation FOXP-CC PF16159.5 KEZ45448.1 - 0.18 12.5 1.9 1.1 9.9 2.0 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain Methyltransf_23 PF13489.6 KEZ45449.1 - 1.4e-17 64.0 0.0 2.4e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45449.1 - 3.8e-10 40.3 0.0 1.2e-09 38.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45449.1 - 7.3e-09 36.2 0.0 1.8e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45449.1 - 2.6e-07 31.3 0.0 2.6e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45449.1 - 3.4e-07 30.2 0.0 0.0018 18.1 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain PrmA PF06325.13 KEZ45449.1 - 0.00099 18.6 0.1 0.002 17.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KEZ45449.1 - 0.0048 16.6 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KEZ45449.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 KEZ45449.1 - 0.017 14.5 0.0 0.3 10.4 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KEZ45449.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FBP_C PF16571.5 KEZ45450.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Peptidase_M3 PF01432.20 KEZ45451.1 - 6.2e-120 401.5 0.0 7.6e-120 401.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KEZ45451.1 - 0.33 10.6 0.4 1.8 8.1 0.1 1.9 2 0 0 2 2 2 0 Peptidase M50B-like CFEM PF05730.11 KEZ45452.1 - 3.9e-09 36.5 6.6 5.1e-09 36.1 6.6 1.2 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_115 PF15979.5 KEZ45453.1 - 6.2e-131 436.8 4.0 8.4e-131 436.4 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KEZ45453.1 - 5.5e-53 179.3 0.1 1.3e-52 178.1 0.1 1.7 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 KEZ45453.1 - 0.003 17.8 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus CblD PF07434.11 KEZ45453.1 - 0.032 13.2 0.2 0.053 12.5 0.2 1.2 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator S_layer_C PF05124.12 KEZ45453.1 - 0.17 11.9 0.3 0.3 11.0 0.3 1.4 1 0 0 1 1 1 0 S-layer like family, C-terminal region CLN3 PF02487.17 KEZ45454.1 - 1.7e-158 527.9 5.9 1.9e-158 527.7 5.9 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KEZ45454.1 - 0.2 10.6 30.9 0.0033 16.4 11.4 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF4536 PF15055.6 KEZ45454.1 - 0.39 11.0 3.0 2.4 8.5 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF2183 PF09949.9 KEZ45455.1 - 2.8e-33 114.2 0.0 5.5e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2434 PF10361.9 KEZ45456.1 - 1.9e-125 417.8 14.2 2.3e-125 417.4 14.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.9 KEZ45457.1 - 7.3e-32 110.3 0.9 7.3e-32 110.3 0.9 2.7 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Polysacc_deac_1 PF01522.21 KEZ45458.1 - 1.1e-26 93.2 0.0 1.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1451 PF07295.11 KEZ45458.1 - 0.035 14.1 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Glyco_hydro_57 PF03065.15 KEZ45458.1 - 0.048 12.9 0.0 0.078 12.2 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Androgen_recep PF02166.16 KEZ45459.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Androgen receptor Glyco_hydro_18 PF00704.28 KEZ45460.1 - 4.2e-41 141.7 0.0 6.1e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KEZ45460.1 - 0.00047 20.6 8.1 0.00047 20.6 8.1 4.2 4 1 1 5 5 5 1 Chitin recognition protein LysM PF01476.20 KEZ45460.1 - 0.016 15.3 0.0 0.31 11.1 0.0 2.6 2 0 0 2 2 2 0 LysM domain Fungal_trans PF04082.18 KEZ45461.1 - 8.8e-17 61.0 0.0 1.4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ45463.1 - 1.1e-23 83.7 64.2 5.4e-23 81.5 49.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3638 PF12340.8 KEZ45464.1 - 3.5e-84 281.6 0.2 1.5e-62 210.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KEZ45464.1 - 2.9e-15 55.4 1.8 4e-15 54.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) Mito_carr PF00153.27 KEZ45465.1 - 7.5e-34 115.5 5.4 8.9e-16 57.6 0.3 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_25 PF13649.6 KEZ45465.1 - 5.9e-12 46.1 0.0 1.4e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45465.1 - 2e-11 44.4 0.0 6.1e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45465.1 - 3.2e-11 43.2 0.0 5.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ45465.1 - 1.2e-10 41.4 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45465.1 - 2.9e-10 40.8 0.0 7.7e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45465.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Ubiq-Cytc-red_N PF09165.10 KEZ45465.1 - 0.11 13.4 0.4 0.11 13.4 0.4 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal SelP_N PF04592.14 KEZ45465.1 - 5.3 6.4 19.2 9.2 5.6 19.2 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Coatomer_WDAD PF04053.14 KEZ45466.1 - 6.6e-145 483.6 0.0 1.1e-144 482.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KEZ45466.1 - 2.3e-97 326.3 0.0 3.8e-97 325.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus SNF2_N PF00176.23 KEZ45466.1 - 3.4e-58 197.1 0.0 5.8e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KEZ45466.1 - 5.6e-42 143.9 0.2 4.1e-41 141.1 0.3 2.2 2 0 0 2 2 2 1 Rad54 N terminal WD40 PF00400.32 KEZ45466.1 - 9e-36 121.3 16.9 2.2e-07 31.5 0.2 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Pkinase PF00069.25 KEZ45466.1 - 3e-20 72.7 0.0 9.2e-20 71.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Helicase_C PF00271.31 KEZ45466.1 - 1.2e-14 54.6 0.0 3.9e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ45466.1 - 1.3e-08 35.1 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ANAPC4_WD40 PF12894.7 KEZ45466.1 - 1.3e-08 35.0 1.5 0.00027 21.2 0.0 5.4 3 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 KEZ45466.1 - 0.0044 16.3 0.5 0.061 12.6 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase HDA2-3 PF11496.8 KEZ45466.1 - 0.011 14.9 0.0 0.034 13.3 0.0 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Clathrin PF00637.20 KEZ45466.1 - 0.11 12.3 0.4 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.8 KEZ45466.1 - 0.19 10.4 5.9 4.9 5.7 0.1 3.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 CSN8_PSD8_EIF3K PF10075.9 KEZ45467.1 - 4.7e-19 68.8 0.0 7.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KEZ45467.1 - 0.18 11.1 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family Sel1 PF08238.12 KEZ45468.1 - 1.2e-13 51.2 29.1 1.3e-05 25.7 0.3 7.7 6 1 1 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 KEZ45468.1 - 0.0031 17.3 0.4 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ45468.1 - 0.13 12.4 0.8 3.9 7.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_24 PF18404.1 KEZ45469.1 - 3.4e-150 498.8 2.9 5.2e-150 498.2 2.9 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KEZ45469.1 - 8.6e-62 209.4 0.0 5.1e-60 203.6 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KEZ45469.1 - 5.3e-54 183.4 0.0 1.2e-51 175.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KEZ45469.1 - 2e-44 151.7 0.0 4.7e-44 150.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KEZ45469.1 - 2.9e-41 140.6 0.0 2.4e-40 137.6 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KEZ45469.1 - 1e-40 138.3 0.0 2.2e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KEZ45469.1 - 4.9e-06 26.3 0.0 9.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 U79_P34 PF03064.16 KEZ45469.1 - 7.5 5.8 8.4 13 5.0 8.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PAS_9 PF13426.7 KEZ45470.1 - 4.3e-25 88.0 0.0 1.7e-17 63.6 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KEZ45470.1 - 5.4e-19 68.3 0.0 1.4e-10 41.3 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KEZ45470.1 - 2.4e-16 59.7 0.0 3e-05 24.0 0.0 3.8 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 KEZ45470.1 - 2.1e-15 56.0 8.0 4.5e-15 55.0 8.0 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 KEZ45470.1 - 7.8e-12 45.4 0.0 0.00017 21.8 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.6 KEZ45470.1 - 6.5e-05 23.0 0.0 0.038 14.1 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 KEZ45470.1 - 0.027 15.2 0.0 0.77 10.4 0.0 2.9 3 0 0 3 3 3 0 PAS fold Importin_rep_4 PF18808.1 KEZ45471.1 - 4.1e-33 113.5 1.2 4.1e-33 113.5 1.2 4.3 6 0 0 6 6 3 1 Importin repeat HEAT_EZ PF13513.6 KEZ45471.1 - 6e-22 77.7 12.1 3.1e-11 43.5 0.1 8.9 7 1 2 9 9 9 3 HEAT-like repeat Importin_rep_5 PF18816.1 KEZ45471.1 - 3.3e-20 72.1 4.7 4e-20 71.9 0.7 3.1 3 0 0 3 3 3 1 Importin repeat HEAT_2 PF13646.6 KEZ45471.1 - 4.4e-19 68.7 10.5 6.1e-08 32.9 0.1 8.5 3 3 4 8 8 8 4 HEAT repeats HEAT PF02985.22 KEZ45471.1 - 1e-17 62.7 11.1 0.0028 17.8 0.0 10.2 11 0 0 11 11 8 4 HEAT repeat Importin_rep_6 PF18829.1 KEZ45471.1 - 8.5e-14 51.6 1.2 8.7e-13 48.4 0.3 3.0 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KEZ45471.1 - 2.2e-11 44.2 0.0 0.0086 16.7 0.0 6.9 5 2 3 8 8 7 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 KEZ45471.1 - 8.7e-09 35.5 0.0 0.2 11.6 0.0 6.1 6 3 0 6 6 5 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 KEZ45471.1 - 3.3e-08 33.5 0.0 0.00017 21.4 0.0 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis DRIM PF07539.12 KEZ45471.1 - 5.2e-08 31.7 1.3 0.0013 17.2 0.2 4.6 4 1 1 5 5 5 2 Down-regulated in metastasis Cnd1 PF12717.7 KEZ45471.1 - 9e-08 32.3 0.3 0.054 13.5 0.0 6.1 5 3 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KEZ45471.1 - 1.8e-07 31.0 0.0 0.006 16.2 0.2 4.9 4 1 1 5 5 5 1 CLASP N terminal MMS19_C PF12460.8 KEZ45471.1 - 6.1e-07 28.9 4.9 8.5e-07 28.4 0.1 3.5 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KEZ45471.1 - 2.9e-05 22.9 1.6 0.0057 15.3 0.2 3.8 3 1 2 5 5 5 1 Adaptin N terminal region Arm PF00514.23 KEZ45471.1 - 4.2e-05 23.4 4.1 0.52 10.4 0.0 5.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KEZ45471.1 - 0.00011 22.0 1.0 0.00097 19.0 0.3 3.1 3 1 0 3 3 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 KEZ45471.1 - 0.00064 19.9 0.9 0.055 13.6 0.3 4.0 3 2 1 4 4 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3535 PF12054.8 KEZ45471.1 - 0.0012 18.2 0.3 0.032 13.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) UNC45-central PF11701.8 KEZ45471.1 - 0.0033 17.4 4.3 0.23 11.4 0.3 4.2 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Telomere_reg-2 PF10193.9 KEZ45471.1 - 0.011 16.2 3.4 0.054 13.9 0.6 3.3 3 0 0 3 3 2 0 Telomere length regulation protein V-ATPase_H_N PF03224.14 KEZ45471.1 - 0.022 14.1 3.1 0.17 11.2 0.1 3.1 3 0 0 3 3 3 0 V-ATPase subunit H TetR_C_1 PF02909.17 KEZ45471.1 - 0.027 14.3 0.5 12 5.7 0.0 3.9 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain TFCD_C PF12612.8 KEZ45471.1 - 0.028 14.3 0.0 4.3 7.1 0.0 3.8 3 1 1 4 4 4 0 Tubulin folding cofactor D C terminal CAS_CSE1 PF03378.15 KEZ45471.1 - 0.04 12.4 0.2 3.9 5.9 0.1 3.3 2 1 2 4 4 4 0 CAS/CSE protein, C-terminus DNA_alkylation PF08713.11 KEZ45471.1 - 0.043 13.5 0.6 0.75 9.5 0.0 3.0 3 0 0 3 3 3 0 DNA alkylation repair enzyme Cnd3 PF12719.7 KEZ45471.1 - 0.071 12.3 0.1 0.94 8.6 0.0 2.7 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 KEZ45471.1 - 0.074 13.4 0.0 3.8 7.9 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 KEZ45471.1 - 0.11 12.2 0.0 9.2 5.9 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4042) CBS PF00571.28 KEZ45472.1 - 1.1e-17 64.3 2.2 4.1e-05 23.9 0.0 5.3 5 0 0 5 5 5 5 CBS domain Ytp1 PF10355.9 KEZ45473.1 - 1.5e-95 319.6 1.1 2.3e-95 319.0 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KEZ45473.1 - 2.4e-29 101.2 6.3 2.4e-29 101.2 6.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Rsa3 PF14615.6 KEZ45473.1 - 4.6e-13 48.5 0.0 1e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TMEM100 PF16311.5 KEZ45473.1 - 0.48 10.0 1.3 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 100 Ca_hom_mod PF14798.6 KEZ45473.1 - 2.9 6.9 4.9 0.96 8.5 0.0 2.4 3 0 0 3 3 3 0 Calcium homeostasis modulator UCH PF00443.29 KEZ45474.1 - 4.8e-33 114.8 0.2 6.8e-33 114.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ45474.1 - 4e-25 89.1 2.4 6.2e-25 88.5 2.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KEZ45474.1 - 0.00034 20.9 0.3 0.00034 20.9 0.3 2.7 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.12 KEZ45474.1 - 9.6 5.8 13.0 1.9 8.1 0.0 4.0 3 1 1 4 4 4 0 TFIIB zinc-binding NAD_binding_10 PF13460.6 KEZ45475.1 - 1e-07 32.1 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ45475.1 - 4.6e-07 29.5 0.0 1.6e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ45475.1 - 3e-06 26.5 0.2 8.6e-06 25.0 0.2 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KEZ45475.1 - 9e-06 25.4 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KEZ45475.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KEZ45475.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain PCI PF01399.27 KEZ45476.1 - 1.7e-12 47.7 0.0 3.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KEZ45476.1 - 1.8e-08 33.8 0.1 4.6e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 KEZ45476.1 - 0.041 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Aconitase PF00330.20 KEZ45477.1 - 2.6e-148 494.9 0.0 3.3e-148 494.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ45477.1 - 5.4e-44 149.7 0.0 9.4e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 KEZ45478.1 - 1e-09 38.4 0.7 2.5e-09 37.2 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KEZ45478.1 - 0.0011 19.3 0.8 0.0022 18.3 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type GH-E PF14410.6 KEZ45478.1 - 0.0069 16.8 0.8 0.023 15.1 0.1 1.9 2 0 0 2 2 2 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues zf-C2H2_4 PF13894.6 KEZ45478.1 - 0.017 15.9 0.8 0.036 14.9 0.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger MCM_OB PF17207.3 KEZ45478.1 - 0.067 13.0 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 MCM OB domain zf-C2H2_2 PF12756.7 KEZ45478.1 - 0.084 13.2 0.4 0.13 12.6 0.4 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CRAL_TRIO PF00650.20 KEZ45479.1 - 2.4e-42 144.3 0.0 5.6e-42 143.2 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KEZ45479.1 - 1.4e-13 50.8 0.1 1.4e-13 50.8 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KEZ45479.1 - 4.5e-07 30.1 0.0 9.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SOAR PF16533.5 KEZ45479.1 - 0.14 12.1 0.1 2.9 7.9 0.1 2.5 2 0 0 2 2 2 0 STIM1 Orai1-activating region HIT PF01230.23 KEZ45480.1 - 1.2e-21 77.2 0.2 1.7e-21 76.8 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KEZ45480.1 - 1.4e-14 54.6 0.0 2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KEZ45480.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ICAT PF06384.11 KEZ45480.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Mog1 PF04603.12 KEZ45481.1 - 5e-38 130.6 0.0 5.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Glucan_synthase PF02364.15 KEZ45482.1 - 0 1362.4 0.0 0 1361.8 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KEZ45482.1 - 5.5e-43 146.4 1.4 1.8e-42 144.8 1.4 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 KEZ45483.1 - 6.5e-30 104.5 0.0 8.8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KEZ45483.1 - 0.0031 16.1 0.0 0.0048 15.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pkinase_fungal PF17667.1 KEZ45484.1 - 2e-102 343.0 0.0 6.3e-102 341.4 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase MauJ PF17419.2 KEZ45484.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ APH PF01636.23 KEZ45484.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family BDV_P24 PF06595.11 KEZ45484.1 - 0.064 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Borna disease virus P24 protein RIO1 PF01163.22 KEZ45484.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HET PF06985.11 KEZ45486.1 - 1.4e-29 103.3 0.0 2.6e-29 102.4 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KEZ45488.1 - 1.1e-33 116.7 31.4 1.7e-33 116.0 31.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.12 KEZ45488.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_M20 PF01546.28 KEZ45489.1 - 1.1e-07 31.7 0.1 2.1e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ45489.1 - 8.9e-07 28.8 0.0 5e-06 26.4 0.0 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.8 KEZ45490.1 - 2.1e-10 40.0 0.1 2.6e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.12 KEZ45491.1 - 1.3e-10 41.5 0.1 6.6e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 KEZ45491.1 - 0.0018 17.5 0.2 0.061 12.5 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain RPN7 PF10602.9 KEZ45491.1 - 0.0085 15.8 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 ABC_tran PF00005.27 KEZ45491.1 - 0.012 16.2 0.5 0.61 10.6 0.0 3.1 3 1 0 3 3 3 0 ABC transporter Phasin PF05597.11 KEZ45491.1 - 0.015 15.3 1.3 0.046 13.7 1.3 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Syntaxin_2 PF14523.6 KEZ45491.1 - 0.026 14.9 2.3 0.034 14.5 0.3 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DASH_Ask1 PF08655.10 KEZ45491.1 - 0.027 14.4 0.1 7.4 6.5 0.0 4.3 5 0 0 5 5 5 0 DASH complex subunit Ask1 DUF2075 PF09848.9 KEZ45491.1 - 0.036 13.3 0.1 3.7 6.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KEZ45491.1 - 0.04 14.2 0.0 0.56 10.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.6 KEZ45491.1 - 0.043 14.2 0.0 0.25 11.7 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 KEZ45491.1 - 0.064 13.0 0.6 0.67 9.7 0.1 2.5 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KEZ45491.1 - 0.071 13.6 0.0 0.26 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 KEZ45491.1 - 0.076 12.6 0.7 0.17 11.4 0.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ank PF00023.30 KEZ45491.1 - 0.15 12.5 0.0 15 6.3 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Viral_helicase1 PF01443.18 KEZ45491.1 - 0.17 11.6 0.5 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SesA PF17107.5 KEZ45491.1 - 0.2 11.8 2.7 0.34 11.1 0.0 2.7 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RNA_helicase PF00910.22 KEZ45491.1 - 0.22 11.9 0.4 0.69 10.3 0.1 2.0 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KEZ45491.1 - 0.25 11.1 0.8 0.47 10.2 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Bacillus_HBL PF05791.11 KEZ45491.1 - 0.54 10.1 4.0 1.2 9.0 4.0 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) COG5 PF10392.9 KEZ45491.1 - 1.2 9.3 5.3 0.53 10.5 1.8 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 MCPsignal PF00015.21 KEZ45491.1 - 1.7 8.4 4.6 5.7 6.7 2.7 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HET PF06985.11 KEZ45493.1 - 5e-21 75.6 0.0 9.8e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 KEZ45494.1 - 1.7e-17 64.1 0.0 3.1e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ45494.1 - 2e-05 24.9 0.3 0.0011 19.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 KEZ45494.1 - 0.00098 19.7 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEZ45494.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEZ45494.1 - 0.0062 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 KEZ45494.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEZ45494.1 - 0.023 15.1 0.2 0.055 13.9 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 KEZ45494.1 - 0.024 15.0 0.1 0.052 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEZ45494.1 - 0.025 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEZ45494.1 - 0.085 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KEZ45494.1 - 0.094 12.1 0.2 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KEZ45494.1 - 0.23 11.4 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Glyco_hydro_61 PF03443.14 KEZ45495.1 - 1.4e-52 178.6 0.1 2.1e-52 178.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAR2 PF16974.5 KEZ45495.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory Cu_bind_like PF02298.17 KEZ45496.1 - 0.012 15.6 0.5 0.03 14.3 0.5 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.20 KEZ45496.1 - 0.03 14.8 0.4 0.052 14.0 0.4 1.4 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Helo_like_N PF17111.5 KEZ45497.1 - 0.00039 19.9 8.3 0.051 12.9 1.0 2.7 3 0 0 3 3 3 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KEZ45497.1 - 0.017 15.3 2.1 0.021 15.0 0.7 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ketoacyl-synt PF00109.26 KEZ45498.1 - 7.5e-67 225.6 0.0 1.8e-66 224.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KEZ45498.1 - 5.7e-59 199.8 0.0 1e-58 199.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KEZ45498.1 - 9.7e-57 191.8 0.3 4.4e-56 189.6 0.1 2.3 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KEZ45498.1 - 1.4e-40 138.0 0.1 3.5e-40 136.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KEZ45498.1 - 1.1e-31 110.5 0.1 2e-31 109.7 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 KEZ45498.1 - 6.6e-19 68.5 0.0 7.5e-18 65.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KEZ45498.1 - 3.3e-14 54.1 0.0 1.4e-12 48.8 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 KEZ45498.1 - 7e-12 45.2 0.0 2.7e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KEZ45498.1 - 3.7e-11 43.6 1.1 2.6e-10 40.9 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45498.1 - 1.4e-09 38.5 0.0 1.1e-08 35.6 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ45498.1 - 4e-09 36.5 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KEZ45498.1 - 1.7e-08 34.5 0.0 1.6e-07 31.4 0.0 2.7 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 KEZ45498.1 - 2e-08 34.5 0.3 5.7e-08 33.0 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KEZ45498.1 - 5e-07 29.6 0.0 1.8e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45498.1 - 2.7e-06 26.9 0.0 4.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family KAsynt_C_assoc PF16197.5 KEZ45498.1 - 9.4e-06 26.1 0.0 3.5e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 KEZ45498.1 - 6.1e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KEZ45498.1 - 0.0062 15.7 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEZ45498.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KEZ45498.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEZ45498.1 - 0.041 13.8 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 KEZ45498.1 - 0.051 13.0 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sun2_CC2 PF18580.1 KEZ45498.1 - 0.07 13.4 0.1 0.37 11.1 0.1 2.2 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 TrkA_N PF02254.18 KEZ45498.1 - 0.074 13.3 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 1 0 TrkA-N domain Thiolase_N PF00108.23 KEZ45498.1 - 0.075 12.4 0.4 0.4 10.0 0.1 2.2 2 0 0 2 2 2 0 Thiolase, N-terminal domain DUF5319 PF17252.2 KEZ45498.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5319) MBOAT_2 PF13813.6 KEZ45499.1 - 1.1e-16 60.9 0.9 2.8e-16 59.5 0.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 KEZ45500.1 - 6.5e-47 160.3 0.0 1.1e-46 159.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KEZ45501.1 - 1.4e-10 41.3 0.0 2.9e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45501.1 - 2.3e-05 25.0 0.0 0.00017 22.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45501.1 - 7.5e-05 22.6 0.0 0.06 13.1 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45501.1 - 0.00012 22.7 0.0 0.00083 20.0 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45501.1 - 0.00068 20.3 0.0 0.078 13.7 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45501.1 - 0.00079 18.8 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KEZ45501.1 - 0.0051 15.8 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 KEZ45501.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Zn_clus PF00172.18 KEZ45502.1 - 0.15 12.2 2.9 0.28 11.3 2.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KEZ45503.1 - 1.9e-33 115.9 0.0 2.7e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AIG2_2 PF13772.6 KEZ45504.1 - 0.0005 20.4 0.0 0.013 15.9 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family GGACT PF06094.12 KEZ45504.1 - 0.00097 19.7 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AMP-binding PF00501.28 KEZ45505.1 - 2.3e-65 220.9 0.0 3.9e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KEZ45505.1 - 6.9e-45 153.6 0.0 1.1e-24 87.0 0.0 2.8 4 0 0 4 4 4 2 Condensation domain PP-binding PF00550.25 KEZ45505.1 - 2.4e-13 50.2 0.1 3.2e-08 33.8 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KEZ45505.1 - 0.0079 17.2 0.0 0.021 15.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 KEZ45506.1 - 2.1e-28 99.6 0.0 2.2e-21 76.5 0.0 3.0 2 1 1 3 3 3 3 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEZ45506.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pyr_redox_2 PF07992.14 KEZ45507.1 - 4.6e-18 65.5 0.0 9.8e-18 64.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ45507.1 - 9.4e-07 28.9 0.7 0.031 14.3 0.1 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KEZ45507.1 - 6.7e-06 25.4 0.0 1.7e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEZ45507.1 - 1.7e-05 23.7 0.0 0.015 14.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ45507.1 - 0.0003 20.2 0.1 0.31 10.2 0.4 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ45507.1 - 0.00045 19.4 0.0 0.035 13.2 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KEZ45507.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ45507.1 - 0.0054 15.9 0.5 0.015 14.4 0.6 1.7 1 1 1 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 KEZ45507.1 - 0.0062 16.2 3.5 0.0092 15.6 2.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ45507.1 - 0.0067 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEZ45507.1 - 0.035 13.3 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KEZ45507.1 - 0.093 11.6 0.6 0.17 10.7 0.6 1.4 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 KEZ45507.1 - 0.099 11.8 0.0 0.94 8.6 0.0 2.2 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KEZ45507.1 - 0.14 11.5 2.7 0.18 11.1 2.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.18 KEZ45508.1 - 1.4e-33 116.0 0.0 6.2e-33 113.9 0.0 1.9 1 1 1 2 2 2 1 O-methyltransferase domain GST_N_2 PF13409.6 KEZ45509.1 - 8.2e-07 29.2 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEZ45509.1 - 1e-06 29.0 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ45509.1 - 2.5e-05 24.4 0.0 4.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KEZ45509.1 - 0.0018 18.6 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ45509.1 - 0.055 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short PF00106.25 KEZ45510.1 - 5.4e-25 88.0 0.1 3.5e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ45510.1 - 2.5e-13 50.1 0.0 4.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ45510.1 - 5.4e-08 33.0 0.1 9.5e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KEZ45510.1 - 0.0045 16.4 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KEZ45510.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1857 PF08982.11 KEZ45511.1 - 6.7e-23 81.2 0.0 2.5e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1857) CorA PF01544.18 KEZ45511.1 - 7.5e-10 38.6 1.4 7.5e-08 32.0 0.2 2.6 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 KEZ45511.1 - 0.038 14.4 3.1 0.077 13.4 0.4 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SpoVR PF04293.13 KEZ45511.1 - 0.6 8.7 5.9 0.079 11.6 1.5 1.7 2 0 0 2 2 2 0 SpoVR like protein TPR_12 PF13424.6 KEZ45512.1 - 9.6e-12 45.0 6.1 4.3e-05 23.7 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ45512.1 - 8.3e-10 38.3 0.0 1.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 KEZ45512.1 - 3.5e-05 23.4 1.0 0.58 10.1 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.6 KEZ45512.1 - 4.8e-05 23.7 0.0 0.00022 21.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.17 KEZ45512.1 - 0.00085 19.3 1.7 1.8 8.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ45512.1 - 0.0016 18.9 4.0 0.0021 18.5 0.5 3.0 2 1 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 KEZ45512.1 - 0.018 15.5 0.8 6.1 7.4 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ45512.1 - 0.024 14.8 1.4 13 6.1 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF87 PF01935.17 KEZ45512.1 - 0.049 13.7 0.4 0.22 11.6 0.0 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain ATPase_2 PF01637.18 KEZ45512.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_10 PF13374.6 KEZ45512.1 - 0.089 12.7 2.6 5.4 7.0 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ45512.1 - 0.091 13.0 2.9 53 4.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_7 PF12775.7 KEZ45512.1 - 0.11 11.9 0.0 0.59 9.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 KEZ45512.1 - 0.14 12.1 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain CdiI_2 PF18593.1 KEZ45512.1 - 0.27 11.9 2.1 11 6.8 0.1 3.1 2 0 0 2 2 2 0 CdiI immunity protein Peptidase_M49 PF03571.15 KEZ45515.1 - 5.2e-198 658.9 0.0 6e-198 658.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Aa_trans PF01490.18 KEZ45517.1 - 3.3e-25 88.6 37.5 4e-25 88.4 37.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Glyco_hydro_31 PF01055.26 KEZ45518.1 - 5.5e-147 490.5 2.2 7e-147 490.2 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KEZ45518.1 - 1.4e-37 128.5 0.0 2.4e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KEZ45518.1 - 1.7e-12 47.5 1.8 1.7e-12 47.5 1.8 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like Epimerase PF01370.21 KEZ45519.1 - 5.7e-17 62.0 0.0 9.2e-17 61.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ45519.1 - 3.3e-09 36.2 0.0 4.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEZ45519.1 - 8.5e-09 35.6 0.2 1.3e-08 34.9 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KEZ45519.1 - 1.2e-08 34.8 0.1 1.8e-08 34.1 0.0 1.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ45519.1 - 7.4e-07 28.6 0.0 0.00031 20.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 KEZ45519.1 - 0.0035 16.9 0.2 0.006 16.2 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KEZ45519.1 - 0.0036 17.2 1.1 0.024 14.6 1.1 2.1 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KEZ45519.1 - 0.033 13.7 0.3 0.51 9.8 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Ada_Zn_binding PF02805.16 KEZ45520.1 - 2e-29 101.4 2.9 3.4e-29 100.6 2.9 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KEZ45520.1 - 2.1e-09 37.2 0.0 6.7e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KEZ45520.1 - 3.3e-07 30.5 0.0 5.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HNH_2 PF13391.6 KEZ45521.1 - 0.00021 21.3 0.1 0.00043 20.4 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Tyrosinase PF00264.20 KEZ45522.1 - 2.2e-24 87.0 0.3 2.2e-24 87.0 0.3 2.3 2 1 0 2 2 2 1 Common central domain of tyrosinase CsbD PF05532.12 KEZ45523.1 - 1e-06 28.5 0.1 1e-06 28.5 0.1 3.2 2 1 1 3 3 3 1 CsbD-like CBM_4_9 PF02018.17 KEZ45524.1 - 1.8e-09 38.0 0.3 1e-05 25.8 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate binding domain ADH_N PF08240.12 KEZ45525.1 - 2e-23 82.4 1.5 2e-23 82.4 1.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ45525.1 - 2.3e-13 50.3 3.0 9.3e-13 48.3 1.2 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEZ45525.1 - 0.066 12.5 0.5 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain tRNA-synt_1e PF01406.19 KEZ45526.1 - 5.7e-109 364.1 0.0 9.2e-109 363.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KEZ45526.1 - 0.018 13.8 0.2 0.33 9.7 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (M) Methyltransf_23 PF13489.6 KEZ45527.1 - 9e-22 77.7 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45527.1 - 5.2e-14 52.7 0.0 1.7e-13 51.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45527.1 - 2.9e-10 40.1 0.0 3.7e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45527.1 - 6.1e-10 39.6 0.0 1.8e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45527.1 - 1.4e-09 38.6 0.0 3.5e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45527.1 - 1.9e-06 27.4 0.0 1.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KEZ45527.1 - 3.6e-05 23.3 0.0 7.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 KEZ45527.1 - 0.0001 22.5 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ45527.1 - 0.00072 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KEZ45527.1 - 0.011 15.0 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KEZ45527.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KEZ45527.1 - 0.029 13.8 0.0 0.072 12.5 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KEZ45527.1 - 0.063 13.0 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MFS_1 PF07690.16 KEZ45528.1 - 9e-37 126.8 57.9 3.9e-35 121.4 55.6 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 KEZ45528.1 - 1.1e-12 48.1 0.0 2.4e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family DUF899 PF05988.12 KEZ45529.1 - 7.8e-79 264.2 0.0 8.7e-79 264.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 KEZ45529.1 - 0.037 13.9 0.0 0.068 13.1 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family AAA_16 PF13191.6 KEZ45530.1 - 0.0025 18.2 0.0 0.0083 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KEZ45530.1 - 0.0029 18.0 0.0 0.0078 16.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KEZ45530.1 - 0.022 14.9 0.0 0.19 11.8 0.0 2.4 2 0 0 2 2 2 0 Torsin DUF87 PF01935.17 KEZ45530.1 - 0.15 12.2 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 KEZ45530.1 - 0.17 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KEZ45531.1 - 3.1e-23 81.6 26.2 7.1e-06 26.7 0.1 8.4 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ45531.1 - 3.9e-18 65.5 0.0 0.014 15.7 0.0 7.0 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 KEZ45531.1 - 2.6e-14 53.5 0.1 5.4e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 KEZ45531.1 - 2.3e-09 36.7 2.6 0.21 10.5 0.0 5.2 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KEZ45531.1 - 1.7e-06 27.8 0.4 1.9 8.5 0.0 4.4 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat DUF676 PF05057.14 KEZ45531.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Nup160 PF11715.8 KEZ45531.1 - 0.0019 16.9 2.9 0.65 8.6 0.0 4.0 3 1 1 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KEZ45531.1 - 0.0039 16.8 1.3 0.89 9.1 0.5 3.2 1 1 2 3 3 3 2 PQQ-like domain PGAP1 PF07819.13 KEZ45531.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 KEZ45531.1 - 0.0092 16.4 0.0 0.043 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KEZ45531.1 - 0.029 15.0 0.6 0.17 12.5 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Spt4 PF06093.13 KEZ45531.1 - 0.058 13.5 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger eIF2A PF08662.11 KEZ45531.1 - 0.091 12.6 0.1 1 9.2 0.0 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cutinase PF01083.22 KEZ45531.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase adh_short PF00106.25 KEZ45532.1 - 3e-22 79.1 0.0 4.1e-19 68.8 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ45532.1 - 8.3e-15 55.0 0.0 8.4e-13 48.4 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ45532.1 - 3e-06 27.3 0.2 5.3e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ45532.1 - 0.0023 17.1 0.1 0.0032 16.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FAD_binding_3 PF01494.19 KEZ45533.1 - 2.9e-12 46.5 0.8 8.8e-09 35.1 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KEZ45533.1 - 6.1e-08 32.2 0.0 8.5e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ45533.1 - 1.8e-06 27.3 0.1 3.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ45533.1 - 4.3e-06 26.9 0.0 1.4e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KEZ45533.1 - 6.8e-05 21.7 0.0 0.00076 18.3 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 KEZ45533.1 - 0.00014 21.1 0.1 0.00052 19.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ45533.1 - 0.00053 19.5 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ45533.1 - 0.0022 18.5 0.1 0.04 14.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ45533.1 - 0.0087 15.7 0.0 0.032 13.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ45533.1 - 0.015 14.6 0.1 0.24 10.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KEZ45533.1 - 0.032 13.5 0.2 0.08 12.2 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KEZ45533.1 - 0.073 12.1 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KEZ45533.1 - 0.089 11.6 0.1 8.3 5.1 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Armet PF10208.9 KEZ45533.1 - 0.17 11.8 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Aldedh PF00171.22 KEZ45534.1 - 1.1e-159 531.9 0.2 1.2e-159 531.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KEZ45534.1 - 0.004 16.2 0.0 0.0074 15.4 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 KEZ45534.1 - 0.013 15.0 0.1 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF1612 PF07756.12 KEZ45534.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) Fungal_trans PF04082.18 KEZ45535.1 - 3.7e-07 29.4 0.3 6.7e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45535.1 - 9.7e-05 22.4 8.0 0.00022 21.3 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEZ45536.1 - 1e-22 80.6 25.2 6e-16 58.3 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEZ45536.1 - 0.00055 18.4 3.0 0.068 11.4 0.3 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KEZ45536.1 - 0.092 11.6 0.9 0.16 10.8 0.9 1.4 1 0 0 1 1 1 0 MFS_1 like family Methyltransf_24 PF13578.6 KEZ45537.1 - 2.5e-06 28.5 0.0 5.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45537.1 - 0.026 15.2 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45537.1 - 0.057 14.2 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ45537.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF1383 PF07134.11 KEZ45537.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) MFS_5 PF05631.14 KEZ45538.1 - 4.5e-12 45.6 2.1 7.4e-12 44.9 2.0 1.4 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KEZ45538.1 - 1.2e-05 24.4 7.7 1.8e-05 23.8 7.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2157 PF09925.9 KEZ45538.1 - 0.016 15.0 4.2 0.028 14.2 3.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4293 PF14126.6 KEZ45538.1 - 0.017 15.4 2.9 0.017 15.4 2.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) FTA2 PF13095.6 KEZ45539.1 - 7.9e-08 32.2 0.1 6.6e-06 25.9 0.0 2.6 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Amidohydro_2 PF04909.14 KEZ45540.1 - 3.9e-34 118.8 0.1 5.3e-34 118.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase SnoaL_4 PF13577.6 KEZ45541.1 - 1.7e-26 92.8 0.0 4.1e-26 91.6 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain RPE65 PF03055.15 KEZ45542.1 - 8.1e-105 351.7 0.0 9.7e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein OpcA_G6PD_assem PF10128.9 KEZ45542.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit Sugar_tr PF00083.24 KEZ45543.1 - 2.5e-83 280.4 20.0 2.9e-83 280.2 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45543.1 - 1e-19 70.7 36.8 6.3e-17 61.5 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KEZ45543.1 - 0.00049 18.6 5.6 0.00051 18.6 1.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KEZ45543.1 - 0.049 11.9 5.8 0.039 12.2 1.7 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Arylesterase PF01731.20 KEZ45544.1 - 0.0049 17.0 0.0 0.035 14.3 0.0 2.4 1 1 0 1 1 1 1 Arylesterase PilJ_C PF18223.1 KEZ45544.1 - 0.18 12.3 0.0 0.52 10.8 0.0 1.7 1 1 0 1 1 1 0 Pili PilJ C-terminal domain HET PF06985.11 KEZ45545.1 - 5.4e-34 117.6 0.0 8.7e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Molydop_binding PF01568.21 KEZ45545.1 - 0.096 12.7 0.0 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain Aminotran_3 PF00202.21 KEZ45547.1 - 1.5e-67 228.0 0.0 2.1e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HET PF06985.11 KEZ45548.1 - 1.8e-24 86.8 0.0 3.3e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lactonase PF10282.9 KEZ45549.1 - 0.0098 15.2 0.0 0.038 13.3 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF1815 PF08844.10 KEZ45549.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Amidase PF01425.21 KEZ45550.1 - 8.3e-71 239.3 3.6 5.4e-69 233.3 0.8 2.4 2 0 0 2 2 2 2 Amidase bZIP_1 PF00170.21 KEZ45550.1 - 0.0025 17.9 8.2 0.0053 16.8 8.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2353 PF09789.9 KEZ45550.1 - 0.026 13.9 2.1 0.045 13.1 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.9 KEZ45550.1 - 0.34 9.9 2.9 0.53 9.3 2.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KEZ45550.1 - 0.81 8.5 5.5 1.4 7.8 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HSP70 PF00012.20 KEZ45550.1 - 0.95 7.6 3.4 1.4 7.0 3.4 1.1 1 0 0 1 1 1 0 Hsp70 protein MFS_1 PF07690.16 KEZ45551.1 - 1.8e-23 83.0 52.8 1.4e-13 50.5 44.3 4.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Tmemb_14 PF03647.13 KEZ45551.1 - 0.071 13.8 0.0 0.071 13.8 0.0 3.9 2 1 0 3 3 3 0 Transmembrane proteins 14C Tropomyosin_1 PF12718.7 KEZ45552.1 - 0.0021 18.2 10.5 0.0021 18.2 10.5 2.0 2 0 0 2 2 2 1 Tropomyosin like DUF3450 PF11932.8 KEZ45552.1 - 0.0031 16.8 12.6 0.0061 15.9 9.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Laminin_I PF06008.14 KEZ45552.1 - 0.0062 16.3 7.2 0.0062 16.3 7.2 1.5 2 0 0 2 2 2 1 Laminin Domain I zf-C4H2 PF10146.9 KEZ45552.1 - 0.0071 16.7 1.4 0.015 15.6 1.4 1.6 1 0 0 1 1 1 1 Zinc finger-containing protein FliJ PF02050.16 KEZ45552.1 - 0.077 13.2 0.8 0.077 13.2 0.8 3.1 2 1 0 3 3 3 0 Flagellar FliJ protein Phage_Nu1 PF07471.12 KEZ45552.1 - 0.12 12.1 4.2 0.25 11.1 4.2 1.5 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 FAM184 PF15665.5 KEZ45552.1 - 0.14 11.9 10.5 0.35 10.6 10.5 1.6 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Cep57_CLD_2 PF14197.6 KEZ45552.1 - 0.32 11.1 13.2 0.061 13.4 6.3 2.8 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 KEZ45552.1 - 0.45 9.3 10.4 0.83 8.5 10.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 KEZ45552.1 - 0.49 10.5 10.2 1.1 9.3 10.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 KEZ45552.1 - 1.5 9.0 17.8 0.12 12.6 11.4 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KEZ45552.1 - 2 7.9 7.2 3.5 7.1 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit YkyA PF10368.9 KEZ45552.1 - 2.8 7.6 16.4 0.031 14.0 7.1 2.3 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Prominin PF05478.11 KEZ45552.1 - 2.9 5.7 5.3 4.2 5.2 5.3 1.2 1 0 0 1 1 1 0 Prominin SesA PF17107.5 KEZ45553.1 - 4e-29 101.3 0.2 1.6e-28 99.3 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KEZ45553.1 - 8.9e-07 29.0 0.0 2.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KEZ45553.1 - 0.004 16.4 0.0 0.0094 15.2 0.0 1.6 1 0 0 1 1 1 1 KAP family P-loop domain CCDC-167 PF15188.6 KEZ45553.1 - 0.0063 16.8 2.9 0.0063 16.8 2.9 2.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 AAA PF00004.29 KEZ45553.1 - 0.096 13.1 0.1 4.3 7.8 0.0 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2884 PF11101.8 KEZ45553.1 - 0.12 11.9 0.5 1.3 8.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Arg_decarbox_C PF17944.1 KEZ45553.1 - 2.7 8.6 6.3 37 5.0 0.2 3.8 4 1 1 5 5 5 0 Arginine decarboxylase C-terminal helical extension DHR10 PF18595.1 KEZ45553.1 - 2.8 8.0 7.7 1.1 9.3 2.6 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Esterase_phd PF10503.9 KEZ45555.1 - 1.2e-16 60.9 0.0 1.7e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ45555.1 - 1.5e-09 37.6 0.1 3e-09 36.7 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEZ45555.1 - 0.13 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_10 PF00331.20 KEZ45556.1 - 4.9e-80 269.0 0.0 5.9e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_1 PF00232.18 KEZ45556.1 - 0.0012 17.3 0.1 0.0019 16.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3759 PF12585.8 KEZ45558.1 - 4.3e-36 122.8 2.7 5.2e-36 122.6 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ABC2_membrane PF01061.24 KEZ45559.1 - 1.9e-74 249.6 55.0 1e-43 149.2 21.1 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ45559.1 - 3.1e-38 131.4 0.1 2.7e-19 70.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KEZ45559.1 - 7e-21 73.9 4.9 2.3e-18 65.9 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KEZ45559.1 - 1.8e-09 37.2 3.0 1.8e-09 37.2 3.0 3.0 2 1 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KEZ45559.1 - 1.2e-07 31.7 0.5 9.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 KEZ45559.1 - 1.9e-06 27.9 0.0 0.12 12.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KEZ45559.1 - 1.3e-05 25.6 0.1 0.0038 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KEZ45559.1 - 3.7e-05 23.5 0.0 0.34 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KEZ45559.1 - 0.002 17.8 0.1 0.036 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ45559.1 - 0.0033 17.7 0.0 0.56 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KEZ45559.1 - 0.0075 16.8 0.0 0.85 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEZ45559.1 - 0.011 16.0 0.2 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KEZ45559.1 - 0.019 15.2 0.1 0.38 11.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEZ45559.1 - 0.023 14.8 0.1 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KEZ45559.1 - 0.056 13.6 0.0 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KEZ45559.1 - 0.075 12.6 0.2 0.77 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KEZ45559.1 - 0.1 12.3 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KEZ45559.1 - 0.14 12.1 0.1 0.79 9.6 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KEZ45559.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rootletin PF15035.6 KEZ45560.1 - 0.0082 16.2 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Peptidase_S8 PF00082.22 KEZ45561.1 - 1.4e-35 123.0 2.0 3e-35 121.9 2.0 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KEZ45561.1 - 3.4e-20 72.5 0.3 1.1e-19 70.8 0.1 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 Peptidase_M28 PF04389.17 KEZ45562.1 - 9.3e-37 126.6 0.1 1.3e-36 126.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEZ45562.1 - 3.3e-17 62.3 1.4 6.8e-17 61.3 1.4 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KEZ45562.1 - 0.00023 20.9 0.2 0.00086 19.1 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Glyco_hydro_114 PF03537.13 KEZ45563.1 - 9.1e-52 175.7 0.0 1.1e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 NACHT PF05729.12 KEZ45564.1 - 0.00045 20.2 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 KEZ45564.1 - 0.097 12.4 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ45564.1 - 0.2 11.9 0.3 1.1 9.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain Alk_phosphatase PF00245.20 KEZ45565.1 - 3.7e-71 240.3 0.0 2.5e-70 237.6 0.0 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 KEZ45565.1 - 2.8e-07 30.3 0.1 4.3e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KEZ45565.1 - 4.1e-06 26.6 0.0 6.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KEZ45565.1 - 0.0028 16.3 0.6 0.0077 14.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KEZ45565.1 - 0.071 12.5 2.2 0.22 10.8 0.2 2.3 3 0 0 3 3 3 0 Metalloenzyme superfamily DUF1501 PF07394.12 KEZ45565.1 - 0.086 11.9 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CENP-Q PF13094.6 KEZ45566.1 - 0.00055 20.2 8.0 0.00055 20.2 8.0 2.2 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.11 KEZ45566.1 - 0.0016 17.4 9.2 0.0034 16.3 9.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein SHE3 PF17078.5 KEZ45566.1 - 0.1 12.3 6.2 1.4 8.6 6.2 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 CwsA PF10814.8 KEZ45566.1 - 0.28 11.4 2.6 0.69 10.1 2.6 1.7 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Fez1 PF06818.15 KEZ45566.1 - 0.36 11.2 13.9 0.41 11.1 12.1 1.8 2 0 0 2 2 2 0 Fez1 Lebercilin PF15619.6 KEZ45566.1 - 0.4 10.3 16.4 0.9 9.2 16.4 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 KEZ45566.1 - 0.41 10.1 13.4 1.4 8.3 12.7 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Prominin PF05478.11 KEZ45566.1 - 0.71 7.7 4.1 1 7.2 4.1 1.1 1 0 0 1 1 1 0 Prominin TMPIT PF07851.13 KEZ45566.1 - 0.79 8.9 3.5 0.78 8.9 0.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein GAS PF13851.6 KEZ45566.1 - 0.95 8.8 13.0 0.67 9.3 10.3 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KEZ45566.1 - 1.2 9.2 20.5 14 5.7 0.2 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LMBR1 PF04791.16 KEZ45566.1 - 1.9 7.3 6.1 2.6 6.8 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6_N PF17675.1 KEZ45566.1 - 2 9.0 18.2 3.3 8.2 10.7 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 KEZ45566.1 - 3.7 7.9 11.3 9.6 6.5 6.6 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) TolA_bind_tri PF16331.5 KEZ45566.1 - 4.2 7.5 13.5 1 9.5 3.3 2.7 3 0 0 3 3 3 0 TolA binding protein trimerisation HSP70 PF00012.20 KEZ45567.1 - 1e-09 37.2 2.6 9.4e-06 24.1 0.2 2.9 3 0 0 3 3 3 3 Hsp70 protein UDPGT PF00201.18 KEZ45570.1 - 2.2e-07 30.1 0.0 5.4e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KEZ45570.1 - 0.086 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_3_C PF01915.22 KEZ45572.1 - 1.5e-57 194.9 0.0 1.5e-56 191.6 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ45572.1 - 2.1e-53 181.7 0.0 4.2e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ45572.1 - 5.9e-18 64.7 0.1 8.5e-17 61.0 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KEZ45572.1 - 1.7e-06 27.9 0.0 3.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 KEZ45572.1 - 0.16 12.2 0.1 0.42 10.9 0.1 1.6 1 0 0 1 1 1 0 CARDB Sugar_tr PF00083.24 KEZ45573.1 - 4.4e-69 233.5 16.9 1.1e-68 232.2 12.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45573.1 - 6.6e-19 68.0 27.4 2.4e-13 49.7 14.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Phage_CP76 PF06892.11 KEZ45573.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) GPI2 PF06432.11 KEZ45573.1 - 1.5 8.2 7.4 0.16 11.4 0.4 2.2 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Ni_hydr_CYTB PF01292.20 KEZ45573.1 - 2 8.0 7.3 0.58 9.7 2.7 2.2 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4133 PF13571.6 KEZ45573.1 - 6.2 7.2 11.1 0.14 12.5 2.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) GFO_IDH_MocA PF01408.22 KEZ45574.1 - 1.8e-19 70.7 0.1 9.6e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.22 KEZ45575.1 - 1.1e-18 68.1 0.0 2.2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KEZ45575.1 - 0.015 15.9 0.0 0.025 15.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEZ45575.1 - 0.17 12.5 0.0 0.76 10.4 0.0 2.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KEZ45577.1 - 7.1e-32 110.7 0.0 1.2e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEZ45577.1 - 1.6e-12 47.9 0.0 4.2e-12 46.5 0.0 1.8 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.12 KEZ45577.1 - 1.4e-05 24.8 0.1 0.27 10.8 0.0 3.2 1 1 2 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Ldl_recept_b PF00058.17 KEZ45577.1 - 2.4e-05 24.7 0.0 0.074 13.5 0.0 4.1 4 0 0 4 4 4 1 Low-density lipoprotein receptor repeat class B NHL PF01436.21 KEZ45577.1 - 6.9e-05 22.7 0.2 0.056 13.5 0.0 4.5 5 0 0 5 5 5 1 NHL repeat Str_synth PF03088.16 KEZ45577.1 - 0.00038 20.5 0.0 1.1 9.4 0.0 3.8 4 0 0 4 4 3 1 Strictosidine synthase NAD_binding_2 PF03446.15 KEZ45577.1 - 0.00086 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KEZ45577.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KEZ45577.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KEZ45577.1 - 0.0054 16.0 0.0 0.052 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KEZ45577.1 - 0.014 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PQQ_3 PF13570.6 KEZ45577.1 - 0.016 15.7 1.8 0.16 12.5 0.1 3.4 3 1 1 4 4 4 0 PQQ-like domain PQQ PF01011.21 KEZ45577.1 - 0.052 13.5 1.8 0.18 11.8 0.1 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat Pyr_redox PF00070.27 KEZ45577.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KEZ45577.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding APH PF01636.23 KEZ45578.1 - 0.011 15.7 0.2 0.022 14.7 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_1 PF00175.21 KEZ45579.1 - 1.5e-31 109.3 0.0 5.4e-31 107.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEZ45579.1 - 4.4e-31 107.2 0.0 1.1e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KEZ45579.1 - 5.9e-22 77.6 0.0 1.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KEZ45579.1 - 5.3e-06 26.6 0.0 0.00058 20.0 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain p450 PF00067.22 KEZ45580.1 - 9e-65 219.2 0.0 1.1e-64 218.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KEZ45581.1 - 3.1e-06 27.2 9.7 5.8e-06 26.3 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bacillus_HBL PF05791.11 KEZ45581.1 - 0.2 11.4 0.2 2.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) His_Phos_1 PF00300.22 KEZ45582.1 - 1.5e-08 34.6 0.0 3.3e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SMYLE_N PF18615.1 KEZ45582.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Ank_2 PF12796.7 KEZ45583.1 - 3e-34 117.5 0.0 7.7e-15 55.3 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ45583.1 - 2.4e-29 100.5 3.6 2.3e-06 27.8 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 KEZ45583.1 - 2.1e-26 89.0 3.0 1.1e-05 25.4 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 KEZ45583.1 - 5.5e-24 84.2 0.4 9.5e-08 32.4 0.1 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ45583.1 - 1.7e-23 82.4 3.5 1.2e-07 31.8 0.1 6.5 2 2 5 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ45583.1 - 2.3e-13 50.4 0.0 5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 KEZ45583.1 - 8.4e-13 48.9 8.1 9.6e-11 42.2 1.4 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 KEZ45583.1 - 7.5e-10 39.4 0.7 4.5e-09 36.9 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEZ45583.1 - 0.0013 19.0 0.0 0.0033 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KEZ45583.1 - 0.0014 18.0 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KEZ45583.1 - 0.0082 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 KEZ45583.1 - 0.018 14.3 0.1 0.11 11.7 0.0 2.0 1 1 0 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.6 KEZ45583.1 - 0.025 14.3 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEZ45583.1 - 0.054 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KEZ45583.1 - 0.056 13.4 0.0 2 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEZ45583.1 - 0.058 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ45583.1 - 0.095 13.1 0.0 0.36 11.3 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KEZ45583.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 KEZ45583.1 - 0.14 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KEZ45583.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family SKG6 PF08693.10 KEZ45584.1 - 0.0099 15.3 0.7 0.0099 15.3 0.7 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CoatB PF10389.9 KEZ45584.1 - 2.7 7.9 8.6 1.2 9.0 4.1 2.5 2 0 0 2 2 2 0 Bacteriophage coat protein B Fic PF02661.18 KEZ45585.1 - 1.4e-16 61.1 0.0 4.2e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family Sugar_tr PF00083.24 KEZ45586.1 - 6.2e-61 206.6 10.7 1.8e-34 119.4 0.4 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45586.1 - 2.6e-07 29.9 8.1 2.6e-07 29.9 8.1 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KEZ45587.1 - 1.3e-15 57.2 1.3 2.4e-15 56.3 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 KEZ45588.1 - 6.5e-33 114.1 0.0 1.1e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 KEZ45589.1 - 5.1e-19 68.7 0.0 9.4e-18 64.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ45589.1 - 1.5e-08 34.6 2.5 0.0033 17.1 2.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ45589.1 - 2.9e-08 33.3 0.1 0.00052 19.3 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ45589.1 - 4.2e-06 26.1 2.2 6.6e-06 25.5 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KEZ45589.1 - 5.4e-06 25.4 0.3 0.00024 19.9 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KEZ45589.1 - 5.5e-06 26.5 3.4 2e-05 24.7 1.1 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ45589.1 - 0.00018 20.8 0.1 0.00032 20.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KEZ45589.1 - 0.00083 18.3 0.1 0.055 12.3 0.1 2.3 2 1 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KEZ45589.1 - 0.002 17.5 1.5 0.0032 16.9 1.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ45589.1 - 0.0069 15.5 1.4 0.049 12.7 1.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KEZ45589.1 - 0.0087 16.6 0.1 0.13 12.8 0.0 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEZ45589.1 - 0.015 14.3 0.0 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 KEZ45589.1 - 0.046 12.8 2.2 0.074 12.1 2.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 2-oxoacid_dh PF00198.23 KEZ45590.1 - 7.1e-30 104.2 0.0 1.2e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEZ45590.1 - 1.2e-14 53.9 1.6 2.1e-14 53.1 1.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Pkinase PF00069.25 KEZ45590.1 - 4.7e-11 42.6 0.0 8.6e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain VWA_2 PF13519.6 KEZ45590.1 - 3.7e-06 27.6 0.0 1.2e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEZ45590.1 - 0.11 12.7 0.0 0.4 10.9 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain CorA PF01544.18 KEZ45591.1 - 7.2e-05 22.2 0.2 0.00013 21.4 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein BTP PF05232.12 KEZ45591.1 - 0.12 12.5 3.9 0.28 11.3 0.8 2.2 2 0 0 2 2 2 0 Chlorhexidine efflux transporter MafB19-deam PF14437.6 KEZ45592.1 - 1.6e-09 37.6 0.0 2.1e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KEZ45592.1 - 7.3e-09 35.4 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Acetyltransf_1 PF00583.25 KEZ45593.1 - 2.2e-14 53.7 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ45593.1 - 5.9e-08 33.0 0.0 9.7e-08 32.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ45593.1 - 1.8e-06 27.9 0.0 2.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ45593.1 - 1.5e-05 25.7 0.0 1.9e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ45593.1 - 2.7e-05 24.0 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KEZ45593.1 - 0.00059 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KEZ45593.1 - 0.0069 16.5 0.0 0.0089 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain VCBS PF13517.6 KEZ45594.1 - 5.7e-33 113.3 48.8 4.3e-09 36.8 1.8 8.2 4 2 4 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KEZ45594.1 - 1.4e-15 58.2 0.1 3.5e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 KEZ45594.1 - 5.4e-09 35.7 13.0 4 6.8 0.0 8.0 4 2 4 8 8 8 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 KEZ45594.1 - 2e-06 27.9 0.1 3.3e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KEZ45594.1 - 5.7e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Dockerin_1 PF00404.18 KEZ45594.1 - 0.00014 22.0 7.4 9 6.6 0.1 6.3 7 0 0 7 7 7 2 Dockerin type I domain VCBS PF13517.6 KEZ45595.1 - 5.2e-60 199.9 96.2 1.4e-11 44.8 7.6 9.2 3 1 7 10 10 10 9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KEZ45595.1 - 1.3e-14 54.0 60.5 0.0038 17.3 1.7 10.6 10 0 0 10 10 10 8 FG-GAP repeat Lipase_GDSL_2 PF13472.6 KEZ45595.1 - 1.1e-12 48.7 1.2 2e-12 47.9 0.2 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 KEZ45595.1 - 1.8e-12 47.0 21.0 1.1 8.6 0.1 10.4 7 3 3 11 11 11 6 Insecticide toxin TcdB middle/N-terminal region Dockerin_1 PF00404.18 KEZ45595.1 - 7.1e-07 29.3 20.0 1.9 8.8 0.0 9.3 8 1 1 9 9 9 2 Dockerin type I domain PliI PF16743.5 KEZ45595.1 - 3.6e-05 23.5 2.8 32 4.3 0.0 7.3 8 0 0 8 8 8 0 Periplasmic lysozyme inhibitor of I-type lysozyme Itfg2 PF15907.5 KEZ45595.1 - 0.00022 20.4 1.5 23 3.9 0.2 6.4 7 0 0 7 7 7 0 Integrin-alpha FG-GAP repeat-containing protein 2 Lipase_GDSL PF00657.22 KEZ45595.1 - 0.00038 20.5 0.2 0.00069 19.6 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BBS2_Mid PF14783.6 KEZ45595.1 - 0.004 17.2 3.8 6.3 6.9 0.1 5.7 4 2 2 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Ank_2 PF12796.7 KEZ45597.1 - 6.8e-56 186.8 0.3 1.5e-12 48.0 0.0 7.6 4 2 4 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45597.1 - 5.7e-43 144.7 4.4 7.1e-11 42.4 0.1 9.1 2 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 KEZ45597.1 - 1.3e-40 136.0 8.7 2.5e-05 24.5 0.0 10.9 10 1 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 KEZ45597.1 - 7.9e-40 130.3 5.3 0.0002 21.5 0.0 12.2 12 1 1 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KEZ45597.1 - 7.7e-33 112.1 13.2 1.4e-06 28.4 0.1 8.2 8 1 2 10 10 10 6 Ankyrin repeats (many copies) NACHT PF05729.12 KEZ45597.1 - 0.00027 20.9 0.0 0.00064 19.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ45597.1 - 0.004 17.5 0.0 0.017 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain ZZ PF00569.17 KEZ45597.1 - 0.008 16.0 8.7 0.017 14.9 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Peptidase_C1_2 PF03051.15 KEZ45598.1 - 6.7e-152 506.3 0.0 7.7e-152 506.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KEZ45598.1 - 7e-10 39.4 0.2 3.8e-05 23.9 0.1 2.8 2 1 0 2 2 2 2 Papain family cysteine protease SnoaL_4 PF13577.6 KEZ45598.1 - 0.076 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain Glyco_hydro_76 PF03663.14 KEZ45599.1 - 2.4e-148 494.6 4.0 3e-148 494.2 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 AAA PF00004.29 KEZ45600.1 - 2.2e-20 73.4 0.0 4.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ45600.1 - 0.0025 18.2 0.6 0.013 15.9 0.1 2.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KEZ45600.1 - 0.0082 16.4 0.4 0.3 11.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 KEZ45600.1 - 0.082 12.5 0.1 0.56 9.8 0.1 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) COesterase PF00135.28 KEZ45601.1 - 1.4e-77 261.8 0.0 2e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ45601.1 - 4.2e-09 36.6 0.0 3e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ45601.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KEZ45601.1 - 0.13 11.1 0.0 0.59 8.9 0.0 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase MFS_1 PF07690.16 KEZ45602.1 - 8.6e-19 67.7 22.9 8.6e-19 67.7 22.9 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45602.1 - 2e-10 40.1 1.3 2e-10 40.1 1.3 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter FAA_hydrolase PF01557.18 KEZ45603.1 - 7.5e-46 156.5 0.0 8.7e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_S8 PF00082.22 KEZ45604.1 - 1.7e-39 135.9 0.2 1.7e-39 135.9 0.2 1.5 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 KEZ45604.1 - 3.5e-11 43.8 0.0 5.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain Myb_DNA-binding PF00249.31 KEZ45605.1 - 0.56 10.5 2.6 70 3.7 0.1 3.2 3 0 0 3 3 3 0 Myb-like DNA-binding domain HHA PF05321.11 KEZ45605.1 - 1.6 9.1 3.2 13 6.2 0.1 2.9 3 1 0 3 3 3 0 Haemolysin expression modulating protein IIGP PF05049.13 KEZ45606.1 - 8.9e-24 84.2 0.0 1.2e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 KEZ45606.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KEZ45606.1 - 0.003 17.4 0.1 0.31 10.8 0.1 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KEZ45606.1 - 0.0045 17.5 1.0 0.04 14.5 0.7 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 KEZ45606.1 - 0.0052 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KEZ45606.1 - 0.0065 16.4 0.4 0.015 15.2 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KEZ45606.1 - 0.0087 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KEZ45606.1 - 0.025 15.1 0.1 0.045 14.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KEZ45606.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KEZ45606.1 - 0.047 13.8 0.3 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KEZ45606.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 KEZ45606.1 - 0.05 13.8 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KEZ45606.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KEZ45606.1 - 0.092 12.8 0.2 0.092 12.8 0.2 1.8 2 1 0 2 2 1 0 Dynamin family cobW PF02492.19 KEZ45606.1 - 0.17 11.5 0.2 0.38 10.3 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KEZ45606.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Herpes_Helicase PF02689.14 KEZ45606.1 - 0.22 9.4 0.0 0.32 8.8 0.0 1.1 1 0 0 1 1 1 0 Helicase Cu_amine_oxid PF01179.20 KEZ45607.1 - 1.1e-157 525.1 0.0 1.4e-157 524.9 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KEZ45607.1 - 4e-24 84.9 0.2 8.3e-24 83.9 0.2 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KEZ45607.1 - 2.3e-12 47.0 0.0 3.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Homeobox_KN PF05920.11 KEZ45608.1 - 2.5e-16 59.3 0.6 6.4e-16 58.0 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KEZ45608.1 - 7.9e-08 32.0 0.1 1.9e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 KEZ45608.1 - 0.016 15.2 0.1 0.76 9.9 0.0 3.5 3 1 0 3 3 3 0 Tc5 transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 KEZ45608.1 - 0.28 10.7 4.7 1 8.9 1.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2_4 PF13894.6 KEZ45608.1 - 7.5 7.7 9.9 25 6.1 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger COesterase PF00135.28 KEZ45609.1 - 3.9e-82 276.8 0.0 1.1e-81 275.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ45609.1 - 2.5e-07 30.8 0.0 1.4e-05 25.1 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Sugar_tr PF00083.24 KEZ45610.1 - 4e-57 194.1 8.3 2.1e-56 191.7 3.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45610.1 - 2.6e-18 66.1 10.3 4e-18 65.5 9.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEZ45610.1 - 0.00016 20.3 3.2 0.00092 17.9 1.9 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein Glyco_hydro_127 PF07944.12 KEZ45611.1 - 2.4e-108 362.9 0.0 3.5e-108 362.4 0.0 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF1955 PF09205.10 KEZ45612.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) adh_short_C2 PF13561.6 KEZ45613.1 - 2e-10 40.7 0.0 2.6e-07 30.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ45613.1 - 8.9e-08 31.8 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TPR_10 PF13374.6 KEZ45614.1 - 6.7e-52 172.0 7.4 2.6e-12 46.2 0.0 6.8 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ45614.1 - 1.2e-38 131.2 2.5 8e-15 54.9 0.0 5.6 2 1 3 5 5 5 4 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 KEZ45614.1 - 1.4e-26 93.5 0.0 1.3e-24 87.0 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II TPR_7 PF13176.6 KEZ45614.1 - 1.3e-14 53.0 1.9 0.00084 19.2 0.2 5.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ45614.1 - 4.5e-11 42.0 0.9 0.17 12.1 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ45614.1 - 2.3e-10 41.0 0.0 0.46 11.2 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ45614.1 - 1.2e-09 37.6 0.8 0.16 11.8 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ45614.1 - 2.7e-09 36.8 8.3 0.24 12.1 0.0 5.8 6 0 0 6 6 4 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 KEZ45614.1 - 1.7e-08 34.1 0.6 7e-08 32.0 0.6 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_17 PF13431.6 KEZ45614.1 - 2e-07 30.9 1.0 0.85 10.1 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ45614.1 - 8.4e-06 26.2 1.3 4 8.0 0.0 5.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ45614.1 - 0.00016 21.1 5.9 0.057 12.8 0.8 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 KEZ45614.1 - 0.0011 19.1 0.2 18 5.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ45614.1 - 0.0042 17.6 3.2 30 5.5 0.1 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ45614.1 - 0.0052 16.0 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KEZ45614.1 - 0.18 12.7 4.0 2.2e+02 3.1 0.1 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Amidohydro_2 PF04909.14 KEZ45615.1 - 4.4e-40 138.3 0.3 7e-40 137.6 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase ADH_N PF08240.12 KEZ45616.1 - 9.2e-09 35.2 0.2 1.8e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ45616.1 - 1.1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ45616.1 - 0.0015 19.6 0.0 0.0026 18.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NACHT PF05729.12 KEZ45617.1 - 1.1e-11 44.9 0.1 3.3e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ45617.1 - 3.1e-07 30.9 0.3 1.3e-06 28.9 0.3 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ45617.1 - 0.0013 19.0 0.2 0.0075 16.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KEZ45617.1 - 0.0055 17.1 0.1 0.16 12.4 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KEZ45617.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 KEZ45617.1 - 0.018 15.4 0.3 0.58 10.6 0.3 2.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ45617.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KEZ45617.1 - 0.098 11.8 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 KEZ45617.1 - 0.099 11.9 0.1 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Goodbye PF17109.5 KEZ45617.1 - 0.33 11.4 1.9 0.43 11.0 0.2 2.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Methyltransf_23 PF13489.6 KEZ45618.1 - 3.8e-17 62.6 0.0 5.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45618.1 - 9.1e-14 51.9 0.0 1.9e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45618.1 - 8.8e-12 45.5 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45618.1 - 7.1e-10 38.9 0.0 5.1e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45618.1 - 1.3e-09 38.6 0.0 6e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45618.1 - 1.1e-07 31.5 0.0 1.1e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KEZ45618.1 - 0.00026 20.6 0.0 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ45618.1 - 0.002 17.6 0.0 0.0062 16.0 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KEZ45618.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KEZ45618.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 KEZ45618.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_PK PF05891.12 KEZ45618.1 - 0.16 11.4 0.1 0.28 10.7 0.1 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase FAD_binding_3 PF01494.19 KEZ45619.1 - 2.4e-21 76.4 0.0 2.8e-20 72.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ45619.1 - 3.1e-11 43.4 3.7 1.2e-05 25.1 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ45619.1 - 2.2e-09 37.0 0.9 0.00038 19.8 0.4 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ45619.1 - 2.4e-07 30.9 0.5 1.5e-06 28.3 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KEZ45619.1 - 8.5e-07 28.3 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KEZ45619.1 - 1.1e-05 24.7 2.0 2.5e-05 23.5 1.7 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KEZ45619.1 - 1.3e-05 24.2 0.2 0.0035 16.2 0.1 2.9 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KEZ45619.1 - 2.8e-05 23.0 0.8 0.022 13.5 1.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KEZ45619.1 - 0.00048 20.6 0.1 0.036 14.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEZ45619.1 - 0.0015 17.9 0.3 0.45 9.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KEZ45619.1 - 0.0033 16.8 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ45619.1 - 0.0078 15.5 0.6 0.046 13.0 0.2 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ45619.1 - 0.025 13.7 0.5 0.077 12.1 0.2 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Thi4 PF01946.17 KEZ45619.1 - 0.055 12.7 0.4 0.12 11.6 0.4 1.4 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 KEZ45620.1 - 2.3e-39 135.3 23.5 3.5e-39 134.7 23.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Bcl-2_3 PF15286.6 KEZ45620.1 - 0.032 14.9 0.6 0.94 10.2 0.1 2.4 2 0 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like DUF2649 PF10854.8 KEZ45620.1 - 2 8.8 6.5 0.84 10.0 1.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2649) Fungal_trans PF04082.18 KEZ45621.1 - 2.6e-24 85.7 0.2 7.2e-24 84.2 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45621.1 - 5.6e-05 23.2 13.5 0.00011 22.3 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.18 KEZ45622.1 - 3.5e-120 401.2 0.0 1.1e-119 399.5 0.0 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase TPP_enzyme_N PF02776.18 KEZ45622.1 - 6.8e-25 87.6 0.6 9.6e-24 83.9 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEZ45622.1 - 9e-18 64.5 0.0 1.8e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NMO PF03060.15 KEZ45622.1 - 8.6e-08 31.9 0.2 6.4e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase TPP_enzyme_M PF00205.22 KEZ45622.1 - 1.8e-06 27.7 0.0 5.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain IMPDH PF00478.25 KEZ45622.1 - 3.3e-05 23.0 0.1 0.00017 20.7 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 KEZ45622.1 - 3.8e-05 23.1 0.0 0.22 10.8 0.0 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KEZ45622.1 - 4.7e-05 22.7 0.0 8.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KEZ45622.1 - 0.00056 19.4 0.0 0.0019 17.7 0.0 1.9 2 1 1 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.21 KEZ45622.1 - 0.012 14.9 0.0 0.036 13.3 0.0 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Aldedh PF00171.22 KEZ45623.1 - 5.9e-131 437.2 0.0 6.8e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SPW PF03779.14 KEZ45623.1 - 0.11 12.2 0.5 0.27 10.8 0.5 1.7 1 0 0 1 1 1 0 SPW repeat APH PF01636.23 KEZ45624.1 - 2.6e-10 40.7 0.0 3.9e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ45624.1 - 6.6e-05 22.6 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KEZ45624.1 - 0.049 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 KEZ45624.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 KEZ45625.1 - 1.4e-25 89.7 0.0 1.1e-07 32.4 0.0 5.7 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45625.1 - 1.4e-21 76.5 0.0 3.2e-05 24.4 0.0 6.7 4 1 3 7 7 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45625.1 - 1.5e-15 55.7 0.0 0.47 11.2 0.0 8.8 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 KEZ45625.1 - 2.5e-13 49.8 0.2 1.2 9.7 0.0 8.0 8 0 0 8 8 7 3 Ankyrin repeat Ank_5 PF13857.6 KEZ45625.1 - 2.5e-11 43.6 0.1 0.0017 18.6 0.0 6.5 5 2 2 7 7 7 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 KEZ45625.1 - 8.2e-06 26.3 0.0 3.4e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KEZ45625.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KEZ45625.1 - 0.0022 18.3 0.0 0.0087 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Hydrolase_4 PF12146.8 KEZ45625.1 - 0.013 14.8 0.1 0.051 12.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AAA PF00004.29 KEZ45625.1 - 0.014 15.8 0.0 0.11 12.9 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.14 KEZ45625.1 - 0.017 14.7 0.0 0.085 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ45625.1 - 0.029 15.0 4.7 0.077 13.6 3.3 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family KAP_NTPase PF07693.14 KEZ45625.1 - 0.035 13.3 0.3 0.37 10.0 0.0 2.1 1 1 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 KEZ45625.1 - 0.047 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ45625.1 - 0.12 12.8 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Cutinase PF01083.22 KEZ45625.1 - 0.2 11.6 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 Cutinase FSH1 PF03959.13 KEZ45626.1 - 4.4e-34 118.0 0.0 5e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 KEZ45627.1 - 8.1e-78 261.5 0.0 2.5e-77 259.9 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ45627.1 - 9.1e-65 217.9 0.0 2.1e-64 216.8 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KEZ45627.1 - 3.6e-63 213.6 0.1 6.3e-63 212.8 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KEZ45627.1 - 1e-48 166.5 0.9 2.1e-48 165.5 0.4 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KEZ45627.1 - 8.3e-37 125.8 0.0 2.5e-36 124.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KEZ45627.1 - 6.1e-20 71.8 0.0 1.6e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KEZ45627.1 - 9.4e-18 65.5 0.0 7.1e-17 62.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ45627.1 - 6.7e-16 58.5 0.1 2.7e-15 56.5 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 KEZ45627.1 - 2.8e-15 56.7 0.4 6.1e-12 46.0 0.0 2.7 1 1 1 2 2 2 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEZ45627.1 - 2e-12 47.0 3.0 6.9e-12 45.2 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KEZ45627.1 - 5.7e-11 43.0 0.1 1.5e-09 38.4 0.0 3.3 4 0 0 4 4 2 1 Methyltransferase domain adh_short_C2 PF13561.6 KEZ45627.1 - 4.4e-09 36.2 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 KEZ45627.1 - 5.6e-09 36.1 0.0 1.2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45627.1 - 7e-09 36.2 0.0 2.4e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KEZ45627.1 - 3.4e-08 33.7 0.0 1.1e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 KEZ45627.1 - 4.5e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 KEZ45627.1 - 1.5e-06 28.1 0.2 3.3e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 KEZ45627.1 - 4.8e-05 22.8 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KEZ45627.1 - 7.2e-05 22.3 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 KEZ45627.1 - 0.0071 15.4 0.1 0.047 12.7 0.0 2.4 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.25 KEZ45627.1 - 0.047 13.1 3.8 0.081 12.3 0.2 2.7 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme SAT PF16073.5 KEZ45627.1 - 0.052 13.3 2.8 1.3 8.7 0.4 3.6 3 1 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Epimerase PF01370.21 KEZ45627.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ45627.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Transferase PF02458.15 KEZ45628.1 - 8.7e-09 34.5 0.0 3e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Transferase family Aldo_ket_red PF00248.21 KEZ45629.1 - 8e-47 159.8 0.0 9e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KEZ45632.1 - 2.7e-28 98.9 36.6 2.7e-28 98.9 36.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sigma_M_inh PF17453.2 KEZ45632.1 - 0.11 13.0 5.2 0.25 11.8 5.2 1.6 1 0 0 1 1 1 0 Sigma-M inhibitor STI1 PF17830.1 KEZ45632.1 - 0.24 11.4 1.2 23 5.0 0.2 2.3 2 0 0 2 2 2 0 STI1 domain DIOX_N PF14226.6 KEZ45633.1 - 4.6e-18 66.1 0.1 9.2e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ45633.1 - 2.2e-16 60.2 0.1 4.7e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MGTL PF17059.5 KEZ45633.1 - 4.7 7.2 5.0 2.5 8.0 1.9 2.1 2 0 0 2 2 2 0 MgtA leader peptide AA_permease PF00324.21 KEZ45634.1 - 3.9e-130 434.7 36.6 4.4e-130 434.5 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KEZ45634.1 - 1.2e-32 113.3 43.0 1.7e-32 112.8 43.0 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KEZ45635.1 - 2.3e-25 89.3 59.6 1.5e-23 83.3 54.7 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45635.1 - 7.6e-10 38.2 7.5 7.6e-10 38.2 7.5 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KEZ45635.1 - 9.8e-05 20.8 2.1 9.8e-05 20.8 2.1 2.3 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Cytomega_TRL10 PF06084.11 KEZ45635.1 - 1.5 8.9 5.4 19 5.3 0.1 2.6 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Fungal_trans_2 PF11951.8 KEZ45637.1 - 4.7e-05 22.4 0.2 6.6e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 KEZ45638.1 - 3.3e-52 177.1 4.0 7.7e-52 175.9 4.0 1.6 1 1 0 1 1 1 1 RTA1 like protein MMPL PF03176.15 KEZ45638.1 - 0.29 10.0 3.3 0.42 9.5 3.3 1.2 1 0 0 1 1 1 0 MMPL family DUF1223 PF06764.11 KEZ45639.1 - 4.4e-07 30.1 0.0 4.4e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Hydrolase_4 PF12146.8 KEZ45640.1 - 3.9e-07 29.6 0.3 0.00015 21.1 0.3 3.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ45640.1 - 8.2e-07 29.8 0.2 1.7e-06 28.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ45640.1 - 4.1e-05 23.4 0.4 0.00025 20.8 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ45640.1 - 0.00088 18.8 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family FAD_binding_4 PF01565.23 KEZ45641.1 - 5.2e-12 45.7 0.9 1e-11 44.7 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ45641.1 - 2e-11 43.8 0.3 3.4e-11 43.1 0.3 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KEZ45641.1 - 0.075 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Chromate_transp PF02417.15 KEZ45642.1 - 1.9e-56 190.6 36.6 1.2e-33 116.5 15.4 2.4 3 0 0 3 3 3 2 Chromate transporter DUF4064 PF13273.6 KEZ45642.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) DUF4834 PF16118.5 KEZ45642.1 - 1.9 9.5 3.4 4 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Aconitase PF00330.20 KEZ45643.1 - 3.2e-72 244.0 0.1 2.2e-70 238.0 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KEZ45643.1 - 8.3e-06 26.2 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KEZ45643.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus PEP_mutase PF13714.6 KEZ45644.1 - 3.3e-35 121.7 0.2 3.9e-35 121.5 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KEZ45644.1 - 8.2e-19 67.5 0.1 1.2e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Isocitrate lyase family Sua5_yciO_yrdC PF01300.18 KEZ45645.1 - 2.4e-11 43.4 0.0 3.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination MFS_1 PF07690.16 KEZ45646.1 - 2e-17 63.2 43.5 1.1e-11 44.3 11.8 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Oleosin PF01277.17 KEZ45646.1 - 0.92 9.3 8.2 2.3 8.0 6.7 2.5 2 1 0 2 2 2 0 Oleosin MFS_1 PF07690.16 KEZ45647.1 - 2e-47 161.8 23.0 1.1e-42 146.2 12.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily FAM176 PF14851.6 KEZ45647.1 - 0.2 11.3 0.1 0.47 10.1 0.0 1.6 2 0 0 2 2 2 0 FAM176 family Aldo_ket_red PF00248.21 KEZ45648.1 - 1.4e-56 191.9 0.0 1.5e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRL PF13146.6 KEZ45648.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 TRL-like protein family AP_endonuc_2 PF01261.24 KEZ45648.1 - 0.14 11.6 0.0 0.5 9.8 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF4479 PF14794.6 KEZ45648.1 - 0.15 11.9 0.0 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) ADH_zinc_N PF00107.26 KEZ45649.1 - 6e-29 100.7 0.7 1.1e-28 99.8 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ45649.1 - 8.3e-15 56.0 0.0 3.9e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ45649.1 - 2.2e-09 37.2 0.1 5.6e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KEZ45649.1 - 0.00019 21.6 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain p450 PF00067.22 KEZ45650.1 - 8.7e-71 239.0 0.0 1.1e-70 238.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KEZ45651.1 - 2.8e-05 24.1 12.3 2.8e-05 24.1 12.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEZ45652.1 - 1.6e-38 132.6 21.5 1.6e-38 132.6 21.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3522 PF12036.8 KEZ45652.1 - 0.19 12.0 6.0 7.8 6.7 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3522) Piwi PF02171.17 KEZ45653.1 - 7.6e-78 261.8 0.0 1.5e-77 260.8 0.0 1.5 1 1 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KEZ45653.1 - 9.3e-17 61.9 0.0 1.7e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KEZ45653.1 - 3.9e-13 48.8 0.4 9e-13 47.7 0.4 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KEZ45653.1 - 1.2e-11 44.6 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KEZ45653.1 - 1.6e-11 44.3 0.0 5.7e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KEZ45653.1 - 0.025 14.8 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Mid domain of argonaute Zip PF02535.22 KEZ45654.1 - 1.4e-64 218.5 13.8 9.6e-64 215.7 13.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter CBM_11 PF03425.13 KEZ45655.1 - 0.03 14.2 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) LOR PF04525.12 KEZ45656.1 - 3.5e-21 75.6 0.1 4.2e-21 75.4 0.1 1.0 1 0 0 1 1 1 1 LURP-one-related MFS_1 PF07690.16 KEZ45657.1 - 6.1e-16 58.3 78.8 8e-15 54.6 49.0 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KEZ45657.1 - 1.6e-05 24.4 23.4 2.3e-05 23.9 23.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Dioxygenase_C PF00775.21 KEZ45659.1 - 1.8e-07 30.8 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase DUF4198 PF10670.9 KEZ45659.1 - 0.065 13.6 0.0 0.17 12.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) Hemerythrin PF01814.23 KEZ45661.1 - 1.2e-08 35.6 0.2 2.3e-08 34.7 0.2 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF953 PF06110.11 KEZ45662.1 - 3.5e-13 49.2 0.0 4.1e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 KEZ45662.1 - 0.0016 18.2 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AtuA PF07287.11 KEZ45663.1 - 8.1e-124 412.9 0.0 1e-123 412.6 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA GFA PF04828.14 KEZ45663.1 - 3.6e-06 27.2 0.0 8.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CoA_transf_3 PF02515.17 KEZ45664.1 - 6.2e-11 42.0 1.6 3.1e-08 33.1 0.1 4.0 2 2 2 4 4 4 4 CoA-transferase family III polyprenyl_synt PF00348.17 KEZ45665.1 - 1.3e-24 86.6 0.0 1.9e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.22 KEZ45666.1 - 1.1e-37 130.0 0.2 1.8e-37 129.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KEZ45666.1 - 1.8e-20 73.5 4.1 1.3e-12 47.6 2.3 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KEZ45666.1 - 0.00014 21.3 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ45666.1 - 0.00033 20.8 0.4 0.00089 19.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ45666.1 - 0.0052 17.3 1.8 0.02 15.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ45666.1 - 0.022 14.4 2.6 0.24 10.9 0.7 2.4 1 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KEZ45666.1 - 0.027 13.5 0.5 0.44 9.5 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KEZ45666.1 - 0.052 12.8 0.3 0.12 11.5 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KEZ45667.1 - 3e-33 115.3 0.0 3.4e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 KEZ45668.1 - 8.7e-99 331.4 0.0 9.9e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 KEZ45669.1 - 5.8e-30 104.4 0.0 6.9e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.20 KEZ45671.1 - 1.1e-52 179.2 0.1 1.3e-52 179.0 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Methyltransf_2 PF00891.18 KEZ45672.1 - 1e-24 87.1 0.0 1.5e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 KEZ45672.1 - 0.15 11.5 0.0 11 5.4 0.0 2.3 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase Alpha_kinase PF02816.18 KEZ45674.1 - 1.8e-33 116.3 0.3 1.3e-26 93.9 0.0 2.4 1 1 1 2 2 2 2 Alpha-kinase family VWA_2 PF13519.6 KEZ45674.1 - 1.5e-13 51.3 0.1 4.4e-13 49.8 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KEZ45674.1 - 0.00042 20.6 0.0 0.0012 19.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain FB_lectin PF07367.11 KEZ45674.1 - 0.12 12.4 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Fungal fruit body lectin Glyco_hydro_32N PF00251.20 KEZ45675.1 - 7e-05 22.5 0.1 0.00066 19.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Transglut_core PF01841.19 KEZ45675.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily zf-A20 PF01754.16 KEZ45676.1 - 1.2 9.1 3.6 1.9 8.5 0.2 2.8 2 0 0 2 2 2 0 A20-like zinc finger AAA_12 PF13087.6 KEZ45677.1 - 3.9e-22 78.8 0.0 6.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ45677.1 - 1.7e-10 41.1 0.0 1.6e-09 37.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ45677.1 - 2e-06 27.7 0.0 0.0038 17.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KEZ45677.1 - 0.00013 21.8 0.0 2.1 8.0 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KEZ45677.1 - 0.0067 16.8 0.0 0.021 15.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KEZ45677.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Hemerythrin PF01814.23 KEZ45678.1 - 1.4e-08 35.4 11.3 1.4e-08 35.4 11.3 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF1722 PF08349.11 KEZ45678.1 - 0.01 16.1 0.1 0.053 13.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) NAD_binding_1 PF00175.21 KEZ45678.1 - 0.17 12.5 0.3 0.49 11.1 0.2 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FlgN PF05130.12 KEZ45678.1 - 0.44 11.0 5.7 0.16 12.5 3.0 1.6 2 0 0 2 2 2 0 FlgN protein AAA_12 PF13087.6 KEZ45680.1 - 0.059 13.0 0.0 0.57 9.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain Gemini_mov PF01708.16 KEZ45681.1 - 4.4 7.1 0.0 4.4 7.1 0.0 3.5 3 2 2 5 5 5 0 Geminivirus putative movement protein Tannase PF07519.11 KEZ45682.1 - 6.9e-62 209.9 0.0 1.8e-61 208.5 0.0 1.7 2 0 0 2 2 2 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KEZ45682.1 - 0.17 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KEZ45683.1 - 6.2e-23 81.3 37.2 1.9e-18 66.6 9.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEZ45683.1 - 0.048 12.0 2.7 0.14 10.4 2.1 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ABC_tran PF00005.27 KEZ45684.1 - 2.9e-39 134.7 0.1 1.3e-19 71.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KEZ45684.1 - 3.7e-14 53.0 8.2 3.7e-14 53.0 8.2 2.0 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KEZ45684.1 - 8.3e-09 35.2 2.1 0.014 14.9 0.3 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KEZ45684.1 - 2.6e-06 27.7 0.1 0.039 14.0 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 KEZ45684.1 - 3.5e-06 27.3 0.9 0.082 13.2 0.2 3.1 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KEZ45684.1 - 1.3e-05 25.3 0.0 0.34 11.0 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ45684.1 - 1.3e-05 25.6 0.7 0.034 14.5 0.3 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 KEZ45684.1 - 6.1e-05 22.6 0.4 0.046 13.2 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 KEZ45684.1 - 7.7e-05 23.1 0.0 0.22 11.9 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KEZ45684.1 - 8.7e-05 22.2 0.1 0.082 12.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KEZ45684.1 - 0.0001 21.8 0.3 0.099 12.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KEZ45684.1 - 0.00011 22.2 0.6 0.25 11.2 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KEZ45684.1 - 0.00046 20.0 0.5 0.18 11.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KEZ45684.1 - 0.0011 18.9 0.0 9.4 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KEZ45684.1 - 0.0011 18.2 1.6 0.17 11.0 0.3 2.9 2 1 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 KEZ45684.1 - 0.0013 18.3 0.4 0.27 10.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KEZ45684.1 - 0.0055 16.6 0.2 0.58 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.6 KEZ45684.1 - 0.0071 16.6 0.4 1.1 9.5 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 KEZ45684.1 - 0.0087 15.2 0.3 1.1 8.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KEZ45684.1 - 0.01 14.8 1.2 2.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 KEZ45684.1 - 0.019 15.4 0.1 2.3 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 KEZ45684.1 - 0.024 13.7 1.0 0.67 9.0 0.0 2.5 3 0 0 3 3 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KEZ45684.1 - 0.028 14.1 0.0 4.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.23 KEZ45684.1 - 0.028 14.5 1.5 3 7.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 KEZ45684.1 - 0.052 13.3 0.1 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.7 KEZ45684.1 - 0.061 12.2 0.1 1 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.6 KEZ45684.1 - 0.12 12.9 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEZ45684.1 - 0.12 12.3 0.3 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 KEZ45684.1 - 0.14 11.4 0.3 16 4.7 0.0 2.3 2 0 0 2 2 2 0 KaiC Pox_A32 PF04665.12 KEZ45684.1 - 0.18 11.3 0.1 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein ATP-synt_ab PF00006.25 KEZ45684.1 - 0.18 11.5 0.3 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 KEZ45684.1 - 0.19 11.3 0.8 12 5.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KEZ45684.1 - 0.27 11.7 0.1 5 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 KEZ45685.1 - 0.011 16.4 0.2 0.016 15.8 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_23 PF13489.6 KEZ45686.1 - 8.5e-19 68.0 0.0 1.4e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45686.1 - 1.1e-12 48.5 0.0 4.3e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45686.1 - 7.7e-10 39.3 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45686.1 - 1.9e-09 37.5 0.0 2.6e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45686.1 - 5.2e-09 36.8 0.0 2.3e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ45686.1 - 0.00086 18.8 0.5 0.0038 16.7 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_2 PF00891.18 KEZ45686.1 - 0.0012 18.1 0.0 0.0036 16.6 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain PrmA PF06325.13 KEZ45686.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KEZ45686.1 - 0.0039 16.8 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KEZ45686.1 - 0.054 12.8 0.0 0.64 9.3 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KEZ45687.1 - 1.9e-25 89.4 0.1 4e-25 88.4 0.1 1.5 1 1 0 1 1 1 1 O-methyltransferase domain GAPES3 PF17154.4 KEZ45687.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain MFS_1 PF07690.16 KEZ45688.1 - 1.6e-19 70.1 20.4 3.1e-19 69.1 20.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45688.1 - 1.2e-06 27.7 5.5 0.00022 20.2 1.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 KEZ45689.1 - 1.3e-35 123.1 0.0 2.3e-35 122.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45689.1 - 2.3e-21 76.2 0.0 3.5e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ45689.1 - 1.2e-06 27.6 0.1 3.4e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KEZ45689.1 - 0.0002 20.8 0.0 0.028 13.7 0.0 2.5 2 1 0 2 2 2 2 Kinase-like FTA2 PF13095.6 KEZ45689.1 - 0.052 13.2 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FHA PF00498.26 KEZ45689.1 - 0.13 12.6 0.1 0.37 11.2 0.1 1.8 1 0 0 1 1 1 0 FHA domain PHO4 PF01384.20 KEZ45691.1 - 1.6e-115 385.8 13.1 1.8e-115 385.6 13.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Chitin_bind_1 PF00187.19 KEZ45693.1 - 1.9e-13 50.6 76.1 4.4e-07 30.2 19.4 4.2 3 2 1 4 4 4 3 Chitin recognition protein NACHT PF05729.12 KEZ45694.1 - 0.013 15.4 0.1 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Egh16-like PF11327.8 KEZ45695.1 - 1.8e-40 139.3 6.1 1.8e-40 139.3 6.1 2.4 2 2 0 2 2 2 1 Egh16-like virulence factor FXMRP1_C_core PF12235.8 KEZ45695.1 - 0.58 10.8 12.2 0.98 10.1 12.2 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF3632 PF12311.8 KEZ45698.1 - 1.5e-22 80.9 0.0 2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.11 KEZ45699.1 - 2.2e-25 89.7 0.0 7.3e-25 88.0 0.0 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNA_pol_3_Rpc31 PF11705.8 KEZ45699.1 - 0.23 11.7 9.9 0.42 10.8 9.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3752 PF12572.8 KEZ45699.1 - 0.48 10.9 5.4 0.85 10.1 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Ank_2 PF12796.7 KEZ45700.1 - 1.6e-14 54.3 0.0 8.2e-10 39.1 0.0 3.9 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ45700.1 - 4.6e-12 45.0 0.4 0.014 15.8 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 KEZ45700.1 - 1.1e-11 45.0 3.2 9.7e-05 22.9 0.0 6.5 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 KEZ45700.1 - 4.4e-08 33.2 0.3 2 9.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KEZ45700.1 - 5.8e-06 26.5 0.8 11 6.5 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ferric_reduct PF01794.19 KEZ45701.1 - 6.1e-23 81.3 8.1 6.1e-23 81.3 8.1 2.9 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KEZ45701.1 - 1e-07 32.2 0.1 0.006 16.7 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KEZ45701.1 - 8.4e-05 23.2 0.0 0.0003 21.4 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KEZ45701.1 - 0.0024 18.0 0.1 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Methyltransf_11 PF08241.12 KEZ45703.1 - 0.0051 17.4 0.0 0.0081 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45703.1 - 0.022 15.4 0.0 0.038 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45703.1 - 0.023 15.4 0.0 0.036 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lac_bphage_repr PF06543.12 KEZ45703.1 - 0.055 13.4 0.2 0.22 11.5 0.2 2.0 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Methyltransf_8 PF05148.15 KEZ45703.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 KEZ45703.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KEZ45703.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45703.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KEZ45706.1 - 2.9e-49 167.2 0.0 4.4e-32 111.2 0.1 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KEZ45706.1 - 1.8e-32 111.4 0.0 4.9e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KEZ45706.1 - 1.5e-22 80.0 0.0 2.5e-18 66.4 0.0 3.1 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KEZ45706.1 - 0.045 14.0 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Dioxygenase_C PF00775.21 KEZ45708.1 - 2.2e-08 33.7 0.1 5.6e-08 32.4 0.1 1.7 2 0 0 2 2 2 1 Dioxygenase DUF4360 PF14273.6 KEZ45710.1 - 2.1e-14 53.8 0.0 3e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Acetyltransf_1 PF00583.25 KEZ45711.1 - 5.2e-14 52.5 0.0 7.8e-14 51.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KEZ45711.1 - 4.7e-07 29.7 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KEZ45711.1 - 2.9e-05 24.4 0.0 5.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ45711.1 - 0.00022 21.1 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KEZ45711.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KEZ45711.1 - 0.12 13.0 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_4 PF13637.6 KEZ45712.1 - 1e-13 51.5 0.8 4.3e-08 33.5 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ45712.1 - 8.9e-11 42.2 0.3 0.0025 18.4 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ45712.1 - 4.8e-10 39.5 2.9 0.00038 20.7 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45712.1 - 2.6e-08 33.5 1.4 0.011 16.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KEZ45712.1 - 7.2e-07 29.4 2.4 0.3 11.6 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 KEZ45712.1 - 0.00011 22.0 1.7 0.00073 19.4 0.5 2.7 2 1 0 2 2 2 1 KilA-N domain Fer2_BFD PF04324.15 KEZ45712.1 - 0.19 12.1 0.1 0.58 10.6 0.1 1.8 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain FYVE PF01363.21 KEZ45713.1 - 3.1e-22 78.5 23.0 2.7e-16 59.4 5.6 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KEZ45713.1 - 3.3e-17 61.9 4.6 7.6e-17 60.8 4.6 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KEZ45713.1 - 0.00028 21.0 2.3 0.00028 21.0 2.3 4.0 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KEZ45713.1 - 0.00043 20.5 7.8 0.039 14.2 0.1 3.1 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding ABC_tran_CTD PF16326.5 KEZ45713.1 - 0.023 14.9 0.8 8.3 6.7 0.2 3.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain RIIa PF02197.17 KEZ45713.1 - 0.065 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit zf-C2H2_2 PF12756.7 KEZ45713.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) C6_DPF PF10170.9 KEZ45713.1 - 0.34 11.3 2.4 0.44 11.0 0.2 2.2 2 0 0 2 2 2 0 Cysteine-rich domain DUF16 PF01519.16 KEZ45713.1 - 0.34 11.4 2.8 1.7 9.1 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function DUF16 HypA PF01155.19 KEZ45713.1 - 1.4 8.9 13.1 0.55 10.3 0.4 3.6 4 0 0 4 4 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CK_II_beta PF01214.18 KEZ45713.1 - 1.7 8.4 3.9 2.1 8.1 0.1 2.6 3 0 0 3 3 3 0 Casein kinase II regulatory subunit zinc_ribbon_9 PF14369.6 KEZ45713.1 - 2.6 8.4 9.4 3.1 8.1 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon zf-C2HC5 PF06221.13 KEZ45713.1 - 7.2 6.7 15.9 8.4 6.5 0.1 4.4 3 1 1 4 4 4 0 Putative zinc finger motif, C2HC5-type Sugar_tr PF00083.24 KEZ45714.1 - 1.3e-77 261.6 13.1 1.6e-77 261.3 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45714.1 - 2.5e-18 66.1 26.2 7.9e-17 61.2 21.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ldh_2 PF02615.14 KEZ45715.1 - 7.8e-125 416.4 1.4 8.9e-125 416.3 1.4 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NAD_binding_7 PF13241.6 KEZ45716.1 - 7.3e-30 103.5 0.0 1.2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KEZ45716.1 - 1.4e-26 91.9 0.1 2.1e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KEZ45716.1 - 6.6e-15 54.3 0.6 9.9e-15 53.7 0.6 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KEZ45716.1 - 0.054 12.7 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mito_fiss_reg PF05308.11 KEZ45717.1 - 0.6 10.2 7.4 0.26 11.4 4.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4139 PF13598.6 KEZ45718.1 - 1.3e-34 119.8 0.0 2.8e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KEZ45718.1 - 2.6e-28 98.3 0.1 2.6e-28 98.3 0.1 3.2 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Sas10_Utp3 PF04000.15 KEZ45718.1 - 0.21 12.2 1.4 0.46 11.1 0.2 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Peptidase_S49_N PF08496.10 KEZ45718.1 - 1.9 8.6 8.8 4.9 7.2 8.8 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal XhlA PF10779.9 KEZ45718.1 - 2.2 8.6 7.9 0.45 10.8 0.2 3.0 3 0 0 3 3 3 0 Haemolysin XhlA Methyltransf_10 PF05971.12 KEZ45719.1 - 7.1e-62 209.4 0.0 1.1e-61 208.8 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KEZ45719.1 - 0.00028 20.5 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KEZ45719.1 - 0.0029 17.0 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KEZ45719.1 - 0.0037 17.2 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45719.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sec20 PF03908.13 KEZ45719.1 - 0.098 12.6 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Sec20 p450 PF00067.22 KEZ45720.1 - 1.2e-09 37.5 1.2 0.00029 19.7 0.1 3.0 3 0 0 3 3 3 3 Cytochrome P450 AcetDehyd-dimer PF09290.11 KEZ45720.1 - 0.11 12.7 0.1 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Ank PF00023.30 KEZ45721.1 - 1e-50 168.0 0.0 6.3e-08 32.7 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.7 KEZ45721.1 - 1.1e-49 167.0 0.0 1.7e-16 60.6 0.0 6.4 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45721.1 - 5.8e-48 160.7 1.8 9.8e-09 35.6 0.1 8.2 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KEZ45721.1 - 1.2e-42 143.4 3.7 9.8e-10 38.5 0.0 7.7 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45721.1 - 6.3e-39 127.5 0.0 0.00035 20.8 0.0 8.5 8 0 0 8 8 8 7 Ankyrin repeat HET PF06985.11 KEZ45721.1 - 1.1e-10 42.1 7.8 6.1e-09 36.4 7.8 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KEZ45722.1 - 3.9e-11 42.5 0.0 1.2e-10 40.9 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45722.1 - 1.1e-07 31.9 8.8 1.7e-07 31.2 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-oxogl_dehyd_N PF16078.5 KEZ45722.1 - 0.062 12.9 0.3 0.062 12.9 0.3 1.8 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus 2-oxoacid_dh PF00198.23 KEZ45723.1 - 7.3e-75 251.4 0.1 9.2e-75 251.1 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KEZ45723.1 - 1.5e-18 66.4 0.5 3e-18 65.4 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KEZ45723.1 - 5.9e-11 42.5 0.5 5.9e-11 42.5 0.5 2.1 2 0 0 2 2 2 1 e3 binding domain DUF3614 PF12267.8 KEZ45723.1 - 0.0049 17.4 0.2 0.014 15.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3614) Sec7 PF01369.20 KEZ45724.1 - 8.2e-74 247.3 3.5 2.8e-73 245.5 1.5 2.8 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 KEZ45724.1 - 2.4e-38 131.5 0.8 2.4e-38 131.5 0.8 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KEZ45724.1 - 5.6e-32 109.4 9.6 9.3e-31 105.5 0.0 6.1 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KEZ45724.1 - 1.1e-22 80.6 2.0 7.1e-21 74.7 0.1 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Fip1 PF05182.13 KEZ45725.1 - 2.8e-20 71.6 0.9 4.8e-20 70.8 0.9 1.4 1 0 0 1 1 1 1 Fip1 motif Cytomega_UL20A PF05984.12 KEZ45725.1 - 0.077 13.3 0.7 0.19 12.1 0.7 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Nucleoporin_FG PF13634.6 KEZ45726.1 - 4e-28 98.1 102.8 1.8e-12 47.9 32.0 4.0 2 1 2 4 4 4 3 Nucleoporin FG repeat region LXG PF04740.12 KEZ45726.1 - 0.05 13.3 1.3 0.48 10.1 0.2 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.12 KEZ45726.1 - 0.078 13.0 1.6 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRXRR PF14239.6 KEZ45726.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RRXRR protein Spc7 PF08317.11 KEZ45726.1 - 0.15 10.9 3.3 1.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KEZ45726.1 - 0.17 12.1 0.9 0.7 10.1 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KEZ45726.1 - 0.4 10.7 3.5 5.3 7.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cluap1 PF10234.9 KEZ45726.1 - 0.54 9.6 2.9 0.69 9.3 0.1 2.1 2 1 0 2 2 2 0 Clusterin-associated protein-1 DUF4810 PF16068.5 KEZ45726.1 - 1.8 9.2 4.9 0.85 10.2 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4810) RNA_pol_3_Rpc31 PF11705.8 KEZ45727.1 - 8.4e-49 166.8 6.0 1.1e-48 166.5 6.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sulfate_transp PF00916.20 KEZ45728.1 - 3.3e-91 305.9 17.9 2.6e-90 302.9 17.9 2.0 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEZ45728.1 - 4.6e-08 32.7 0.0 8.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain PIN_8 PF18476.1 KEZ45729.1 - 0.008 16.1 1.4 0.31 10.9 1.6 2.1 2 0 0 2 2 2 1 PIN like domain DUF2570 PF10828.8 KEZ45729.1 - 0.13 12.1 3.9 0.18 11.7 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Jnk-SapK_ap_N PF09744.9 KEZ45729.1 - 0.21 11.8 9.0 0.31 11.2 9.0 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Dynamin_N PF00350.23 KEZ45729.1 - 1.1 9.3 6.2 2.9 7.9 0.0 2.2 1 1 0 2 2 2 0 Dynamin family Casc1_N PF15927.5 KEZ45729.1 - 6.5 6.4 15.2 9.2 5.9 15.2 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus N2227 PF07942.12 KEZ45732.1 - 1.5e-64 217.8 0.0 2.1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 KEZ45732.1 - 2.4e-06 28.1 0.0 6.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45732.1 - 0.0024 18.6 0.2 0.01 16.6 0.0 2.4 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ45732.1 - 0.0087 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF5069 PF16798.5 KEZ45732.1 - 0.018 15.2 0.7 0.47 10.7 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5069) Methyltransf_25 PF13649.6 KEZ45732.1 - 0.051 14.3 0.0 0.16 12.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45732.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF2284 PF10050.9 KEZ45733.1 - 7.9e-07 29.0 142.4 0.88 9.3 1.5 15.4 16 0 0 16 16 16 15 Predicted metal-binding protein (DUF2284) Strep_his_triad PF04270.13 KEZ45733.1 - 2.9e-06 27.2 55.2 13 5.9 0.0 15.0 16 0 0 16 16 16 9 Streptococcal histidine triad protein Cyt-b5 PF00173.28 KEZ45734.1 - 1.5e-16 60.3 0.1 5.5e-10 39.3 0.0 3.8 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Mito_fiss_reg PF05308.11 KEZ45734.1 - 0.046 13.8 2.6 0.12 12.5 2.6 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator S-layer PF07752.11 KEZ45735.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 S-layer protein TPR_2 PF07719.17 KEZ45736.1 - 6.2e-10 38.4 1.4 0.0045 17.0 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ45736.1 - 2.9e-08 33.2 0.1 0.025 14.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ45736.1 - 3.7e-08 33.9 2.2 3.7e-08 33.9 2.2 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ45736.1 - 9.3e-07 29.0 7.1 0.0038 17.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ45736.1 - 9.8e-06 26.0 8.1 0.021 15.6 0.1 4.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ45736.1 - 6.5e-05 23.4 1.7 0.0069 16.9 0.3 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ45736.1 - 0.00019 21.4 0.2 0.42 10.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ45736.1 - 0.00059 19.7 2.3 0.045 13.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ45736.1 - 0.00096 19.3 0.9 0.0044 17.1 0.9 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ45736.1 - 0.001 18.7 0.0 0.013 15.1 0.0 2.8 3 0 0 3 3 3 1 TPR repeat XLF PF09302.11 KEZ45736.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TPR_6 PF13174.6 KEZ45736.1 - 0.28 11.9 2.3 16 6.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.20 KEZ45737.1 - 1.8e-06 26.5 0.0 3.1e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ45737.1 - 0.026 13.4 0.4 0.048 12.5 0.1 1.5 2 0 0 2 2 2 0 MreB/Mbl protein XAP5 PF04921.14 KEZ45738.1 - 4.9e-93 311.5 0.4 4.9e-93 311.5 0.4 1.7 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 KEZ45738.1 - 0.0067 16.9 3.6 0.0067 16.9 3.6 2.9 2 2 1 3 3 3 1 Domain of unknown function (DUF4604) SR-25 PF10500.9 KEZ45738.1 - 0.13 11.8 11.2 0.23 11.1 11.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GYF PF02213.16 KEZ45739.1 - 1.3e-17 63.2 0.2 1.3e-17 63.2 0.2 2.1 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 KEZ45739.1 - 0.0023 17.7 0.0 0.0098 15.7 0.0 2.2 1 0 0 1 1 1 1 GYF domain 2 AltA1 PF16541.5 KEZ45740.1 - 8.5e-09 36.3 0.0 2e-08 35.0 0.0 1.6 1 1 1 2 2 2 1 Alternaria alternata allergen 1 ABC_tran PF00005.27 KEZ45741.1 - 5.3e-48 163.0 0.3 6.9e-25 88.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KEZ45741.1 - 1.8e-32 111.2 0.4 6.4e-32 109.5 0.4 2.1 1 0 0 1 1 1 1 Four helical bundle domain SMC_N PF02463.19 KEZ45741.1 - 3.8e-18 65.8 0.2 4.3e-07 29.6 0.0 3.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ45741.1 - 4.2e-18 66.2 0.2 0.0017 18.2 0.0 5.2 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ45741.1 - 1e-08 36.0 9.1 0.00022 21.8 0.1 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KEZ45741.1 - 1.3e-08 34.4 0.1 0.0075 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KEZ45741.1 - 1.1e-07 31.9 0.0 0.0011 19.0 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KEZ45741.1 - 1.6e-07 31.7 0.0 0.0042 17.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KEZ45741.1 - 1.6e-07 31.4 0.0 0.0022 18.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 KEZ45741.1 - 8e-07 29.4 0.0 0.015 15.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KEZ45741.1 - 6.1e-06 26.8 0.1 0.13 12.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 KEZ45741.1 - 1.1e-05 25.6 0.0 0.00099 19.2 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 KEZ45741.1 - 1.3e-05 25.1 2.5 0.073 12.8 0.0 3.7 5 0 0 5 5 4 2 AAA ATPase domain AAA_16 PF13191.6 KEZ45741.1 - 1.6e-05 25.3 0.4 0.42 11.0 0.0 4.2 5 0 0 5 5 4 1 AAA ATPase domain AAA_33 PF13671.6 KEZ45741.1 - 2.4e-05 24.5 0.1 0.51 10.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KEZ45741.1 - 2.6e-05 24.6 0.0 0.58 10.6 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KEZ45741.1 - 7.1e-05 22.6 0.8 0.061 13.1 0.0 3.2 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 KEZ45741.1 - 7.9e-05 23.0 0.0 0.65 10.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase MeaB PF03308.16 KEZ45741.1 - 0.00013 21.1 0.2 0.33 9.9 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 KEZ45741.1 - 0.00018 21.2 0.0 0.17 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KEZ45741.1 - 0.00027 20.7 0.1 1.3 8.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KEZ45741.1 - 0.00047 20.1 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KEZ45741.1 - 0.00096 19.2 0.1 3.3 7.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 KEZ45741.1 - 0.0012 18.4 0.4 3.9 7.0 0.0 3.7 5 0 0 5 5 3 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 KEZ45741.1 - 0.0014 18.6 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 KEZ45741.1 - 0.0017 18.5 2.9 0.95 9.5 0.0 4.2 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_30 PF13604.6 KEZ45741.1 - 0.0021 17.8 0.0 3.8 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 KEZ45741.1 - 0.0029 16.8 0.2 1.6 7.8 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit NB-ARC PF00931.22 KEZ45741.1 - 0.005 16.1 0.1 0.3 10.2 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 KEZ45741.1 - 0.0054 17.0 0.0 0.95 9.7 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KEZ45741.1 - 0.0075 16.0 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 KEZ45741.1 - 0.0092 16.2 0.0 8.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KEZ45741.1 - 0.01 15.8 0.0 3.3 7.6 0.0 3.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KEZ45741.1 - 0.01 15.6 0.0 6.4 6.5 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 KEZ45741.1 - 0.016 14.5 0.0 2.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Septin CLP1_P PF16575.5 KEZ45741.1 - 0.017 14.9 0.0 0.8 9.5 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP-synt_ab PF00006.25 KEZ45741.1 - 0.019 14.6 0.0 7.2 6.2 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 KEZ45741.1 - 0.02 14.6 0.0 5.6 6.7 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 KEZ45741.1 - 0.024 14.5 0.1 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 KEZ45741.1 - 0.025 14.1 0.0 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 KEZ45741.1 - 0.032 14.0 0.0 6.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 KEZ45741.1 - 0.045 13.1 0.1 3.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KEZ45741.1 - 0.049 12.7 0.1 4.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.6 KEZ45741.1 - 0.076 12.6 0.0 6.4 6.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KEZ45741.1 - 0.084 12.8 0.0 18 5.2 0.0 2.7 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 KEZ45741.1 - 0.11 11.8 0.8 17 4.6 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_5 PF07728.14 KEZ45741.1 - 0.13 12.2 0.0 31 4.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 KEZ45741.1 - 0.15 11.6 0.1 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DAP3 PF10236.9 KEZ45741.1 - 0.32 10.1 6.0 1.5 7.9 0.8 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.6 KEZ45741.1 - 0.42 11.0 3.0 57 4.1 0.0 4.3 3 1 0 3 3 3 0 AAA domain AAA_13 PF13166.6 KEZ45741.1 - 3.7 6.1 12.1 2.4 6.7 0.0 4.2 4 1 0 5 5 5 0 AAA domain Glyco_hydro_61 PF03443.14 KEZ45742.1 - 7.7e-57 192.5 0.3 9.1e-57 192.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PKD_channel PF08016.12 KEZ45743.1 - 1.1e-07 30.9 20.5 8.2e-06 24.7 20.5 2.3 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 KEZ45743.1 - 3.1e-05 23.3 28.8 0.00039 19.7 28.8 2.3 1 1 0 1 1 1 1 Ion transport protein BicD PF09730.9 KEZ45743.1 - 0.36 9.2 0.9 0.49 8.8 0.9 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D AAA PF00004.29 KEZ45744.1 - 2.4e-15 57.1 0.0 8e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KEZ45744.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ45744.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.8 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 KEZ45744.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.9 4 1 0 4 4 4 0 AAA domain Macro PF01661.21 KEZ45745.1 - 1.6e-41 141.1 0.0 2.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Macro domain Tipalpha PF16753.5 KEZ45746.1 - 0.00068 19.5 0.6 0.013 15.3 0.1 2.4 2 0 0 2 2 2 1 TNF-alpha-Inducing protein of Helicobacter Peptidase_S46 PF10459.9 KEZ45746.1 - 0.095 11.3 4.8 0.14 10.7 4.8 1.2 1 0 0 1 1 1 0 Peptidase S46 Fungal_trans PF04082.18 KEZ45747.1 - 2.3e-10 39.9 0.0 3.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45747.1 - 1.3e-05 25.2 8.0 2.2e-05 24.5 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEZ45748.1 - 5.1e-80 269.5 15.5 5.9e-80 269.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45748.1 - 1.2e-13 50.8 25.4 2.1e-11 43.4 18.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KEZ45748.1 - 0.0036 16.2 2.5 0.0036 16.2 2.5 2.2 2 0 0 2 2 2 1 MFS_1 like family Tetraspanin PF00335.20 KEZ45748.1 - 2.2 8.0 7.5 0.076 12.7 0.9 1.9 2 0 0 2 2 2 0 Tetraspanin family Abhydrolase_3 PF07859.13 KEZ45749.1 - 3e-08 33.8 0.0 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ45749.1 - 0.0025 17.3 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.9 KEZ45749.1 - 0.015 14.8 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KEZ45749.1 - 0.086 12.1 0.0 0.47 9.7 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Sulfate_transp PF00916.20 KEZ45750.1 - 1.1e-75 254.8 14.9 1.5e-75 254.4 14.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KEZ45750.1 - 3.8e-17 62.0 0.0 8.3e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KEZ45750.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 KEZ45750.1 - 1.2 9.5 11.9 0.21 12.0 5.6 2.7 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Thiolase_N PF00108.23 KEZ45751.1 - 3.3e-64 216.7 0.0 4.9e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KEZ45751.1 - 1.4e-40 137.8 1.1 3.3e-40 136.6 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain Glyco_hydro_cc PF11790.8 KEZ45752.1 - 9.8e-68 228.3 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GH131_N PF18271.1 KEZ45754.1 - 1.4e-82 277.2 0.0 1.6e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain SIR2 PF02146.17 KEZ45755.1 - 8.3e-21 74.7 0.0 1e-10 41.8 0.0 2.4 2 0 0 2 2 2 2 Sir2 family OATP PF03137.20 KEZ45755.1 - 0.13 10.6 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CHCH PF06747.13 KEZ45756.1 - 3e-06 27.2 4.9 5e-06 26.5 4.9 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KEZ45756.1 - 2.7 8.5 7.9 0.11 12.9 1.9 1.8 2 0 0 2 2 2 0 GCK domain AIF_C PF14721.6 KEZ45756.1 - 9.5 6.6 6.5 0.61 10.5 0.4 1.9 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TPK_catalytic PF04263.16 KEZ45757.1 - 6.8e-25 87.4 0.0 4.3e-24 84.9 0.0 2.1 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KEZ45757.1 - 1.2e-21 76.2 0.0 2.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain NACHT PF05729.12 KEZ45757.1 - 1.2e-08 35.0 0.0 2.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 KEZ45757.1 - 1.2e-05 25.5 0.0 0.00023 21.3 0.0 2.6 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 KEZ45757.1 - 0.00019 21.9 0.0 0.0012 19.3 0.0 2.3 3 0 0 3 3 1 1 AAA ATPase domain Helo_like_N PF17111.5 KEZ45757.1 - 0.0029 17.0 0.0 0.009 15.4 0.0 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins CSN4_RPN5_eIF3a PF18420.1 KEZ45757.1 - 0.0035 17.5 0.1 0.0091 16.1 0.1 1.7 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain ABC_tran PF00005.27 KEZ45757.1 - 0.0054 17.3 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 KEZ45757.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KEZ45757.1 - 0.015 15.5 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ45757.1 - 0.025 15.1 0.0 0.12 12.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ45757.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KEZ45757.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 KEZ45757.1 - 0.11 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KEZ45757.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rootletin PF15035.6 KEZ45757.1 - 0.12 12.3 0.2 0.39 10.7 0.2 1.8 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Rad17 PF03215.15 KEZ45757.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KEZ45757.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KEZ45757.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase 3HCDH_N PF02737.18 KEZ45758.1 - 1.5e-27 96.6 0.0 3e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KEZ45758.1 - 1.3e-18 67.4 0.0 2.4e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.14 KEZ45758.1 - 8.5e-05 21.9 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KEZ45758.1 - 0.00062 19.4 0.0 0.0025 17.4 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KEZ45758.1 - 0.00071 20.1 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KEZ45758.1 - 0.0036 17.5 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KEZ45758.1 - 0.0042 17.1 0.2 0.012 15.6 0.2 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 KEZ45758.1 - 0.007 15.5 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KEZ45758.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ45758.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ45758.1 - 0.027 14.7 0.1 0.055 13.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KEZ45758.1 - 0.047 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 KEZ45758.1 - 0.048 14.2 0.0 0.14 12.7 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Herpes_ICP4_C PF03585.14 KEZ45758.1 - 0.061 12.0 0.0 0.09 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region AlaDh_PNT_C PF01262.21 KEZ45758.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KEZ45760.1 - 3.6e-38 131.4 25.9 3.6e-38 131.4 25.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45760.1 - 2.8e-12 46.3 18.2 4.4e-12 45.6 18.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter AAA PF00004.29 KEZ45761.1 - 5.9e-19 68.8 0.0 1.1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ45761.1 - 0.0036 17.7 0.5 0.018 15.4 0.5 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KEZ45761.1 - 0.0076 16.5 0.7 0.098 12.9 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ45761.1 - 0.08 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEZ45761.1 - 0.089 12.8 0.0 0.56 10.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) tRNA-synt_1b PF00579.25 KEZ45763.1 - 6.3e-33 114.3 0.0 8.8e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DIOX_N PF14226.6 KEZ45764.1 - 2.1e-06 28.5 0.1 3.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ45764.1 - 0.00011 22.7 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KEZ45765.1 - 2e-43 148.7 41.6 3.7e-43 147.8 41.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ45765.1 - 5.2e-17 61.8 13.7 5.2e-17 61.8 13.7 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KEZ45765.1 - 7.5e-06 24.6 9.1 7.5e-06 24.6 9.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Bac_chlorC PF02043.17 KEZ45765.1 - 0.13 12.2 0.1 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein MFS_1 PF07690.16 KEZ45766.1 - 3.1e-43 148.1 51.2 3.1e-43 148.1 51.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ45766.1 - 4.7e-15 55.0 16.4 8.7e-15 54.2 16.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KEZ45766.1 - 7e-10 38.3 12.4 7e-10 38.3 12.4 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter NACHT PF05729.12 KEZ45768.1 - 1.5e-06 28.3 0.2 7.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KEZ45768.1 - 6.9e-06 26.5 0.5 0.00055 20.3 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KEZ45768.1 - 0.005 16.6 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SesA PF17107.5 KEZ45768.1 - 0.0075 16.5 2.6 0.0095 16.1 0.0 2.5 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KEZ45768.1 - 0.0085 16.4 0.0 0.053 13.8 0.0 2.5 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KEZ45768.1 - 0.013 15.9 0.0 0.039 14.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KEZ45768.1 - 0.013 16.0 2.4 0.11 13.0 0.0 3.1 3 1 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 KEZ45768.1 - 0.034 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KEZ45768.1 - 0.054 14.1 0.0 0.42 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KEZ45768.1 - 0.072 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 KEZ45768.1 - 0.1 12.3 0.4 0.45 10.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 KEZ45768.1 - 0.17 12.2 0.2 1.7 9.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain p450 PF00067.22 KEZ45769.1 - 0.0012 17.7 0.1 0.0023 16.8 0.1 1.6 1 1 0 1 1 1 1 Cytochrome P450 Asp_protease PF09668.10 KEZ45769.1 - 0.064 13.0 0.1 5.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease PHO4 PF01384.20 KEZ45770.1 - 7.8e-101 337.5 16.9 9e-101 337.3 16.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Ank_2 PF12796.7 KEZ45771.1 - 4.8e-32 110.4 1.5 9.9e-12 45.3 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ45771.1 - 3.2e-26 91.0 6.1 0.00021 21.5 0.2 7.3 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ45771.1 - 1.3e-22 79.9 1.4 9.4e-08 32.5 0.0 5.4 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45771.1 - 1.5e-22 77.2 4.2 0.03 14.9 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 KEZ45771.1 - 5.2e-20 70.9 20.4 9.7e-05 22.6 0.1 8.0 6 2 1 7 7 7 5 Ankyrin repeat NACHT PF05729.12 KEZ45771.1 - 6.1e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ45771.1 - 0.0011 19.4 0.0 0.0062 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KEZ45771.1 - 0.048 12.9 0.3 1.1 8.4 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.6 KEZ45771.1 - 0.076 13.3 0.1 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF676 PF05057.14 KEZ45772.1 - 1.8e-07 30.9 0.0 2.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ45772.1 - 0.00013 22.7 3.1 0.00073 20.2 3.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEZ45772.1 - 0.00088 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_8 PF06259.12 KEZ45772.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF829 PF05705.14 KEZ45772.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Whi5 PF08528.11 KEZ45773.1 - 9.9e-12 44.2 0.0 1.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like HET PF06985.11 KEZ45774.1 - 1.5e-14 54.5 0.0 2.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_3_C PF01915.22 KEZ45775.1 - 1.5e-53 181.8 0.0 3.3e-53 180.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ45775.1 - 7.2e-42 143.9 0.0 1.1e-41 143.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ45775.1 - 1.6e-26 92.2 0.3 3.5e-26 91.1 0.3 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Cuticle_1 PF08140.11 KEZ45775.1 - 0.039 14.0 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Myb_DNA-bind_3 PF12776.7 KEZ45776.1 - 1.5e-26 93.2 0.3 2.8e-26 92.3 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF5353 PF17304.2 KEZ45777.1 - 1e-16 60.4 0.5 1.5e-16 59.9 0.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Macoilin PF09726.9 KEZ45777.1 - 1.8 7.0 3.3 2.1 6.8 3.3 1.0 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_18 PF00704.28 KEZ45778.1 - 1.9e-55 188.8 0.0 2.6e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BNR PF02012.20 KEZ45778.1 - 2.2 8.6 4.6 14 6.1 0.1 4.0 4 0 0 4 4 4 0 BNR/Asp-box repeat Fungal_trans PF04082.18 KEZ45779.1 - 8.3e-19 67.6 0.2 2.1e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45779.1 - 1.4e-08 34.7 9.9 3.2e-08 33.6 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAP7 PF05672.11 KEZ45780.1 - 0.98 9.1 25.0 0.012 15.3 15.8 2.0 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family FAD_binding_3 PF01494.19 KEZ45781.1 - 5.2e-24 85.1 0.0 8.9e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ45781.1 - 1.5e-09 37.6 0.0 0.00095 18.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ45781.1 - 2.7e-08 33.8 2.1 0.0062 16.2 0.0 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ45781.1 - 3.7e-06 27.4 0.2 0.0034 17.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ45781.1 - 5e-06 25.9 2.7 7.8e-06 25.2 2.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEZ45781.1 - 1.2e-05 24.2 0.7 0.00064 18.5 0.8 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KEZ45781.1 - 1.9e-05 24.8 0.5 0.00012 22.2 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KEZ45781.1 - 8.7e-05 21.8 0.1 0.00028 20.1 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEZ45781.1 - 0.00036 19.9 0.1 0.064 12.5 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KEZ45781.1 - 0.00043 19.3 0.3 0.0093 14.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KEZ45781.1 - 0.0017 17.5 0.3 0.0091 15.1 0.3 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KEZ45781.1 - 0.0023 17.3 0.6 0.0034 16.8 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KEZ45781.1 - 0.0024 17.0 0.1 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 KEZ45781.1 - 0.0031 16.8 0.1 0.0051 16.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KEZ45781.1 - 0.022 14.0 0.1 0.44 9.8 0.1 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KEZ45781.1 - 0.023 13.5 0.0 0.76 8.5 0.0 2.1 2 0 0 2 2 2 0 MCRA family Rossmann-like PF10727.9 KEZ45781.1 - 0.071 13.0 0.1 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Rossmann-like domain Cupin_2 PF07883.11 KEZ45782.1 - 1.2e-11 44.2 0.1 9.8e-08 31.6 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KEZ45782.1 - 0.0011 18.6 0.0 1.8 8.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_4 PF08007.12 KEZ45782.1 - 0.064 12.7 0.2 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Abhydrolase_3 PF07859.13 KEZ45783.1 - 1.6e-13 51.1 0.0 1.8e-09 37.7 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ45783.1 - 9.8e-10 38.3 0.0 2.7e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 KEZ45783.1 - 1.7e-05 24.6 0.1 0.00016 21.4 0.1 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KEZ45783.1 - 0.00039 20.1 0.1 0.61 9.7 0.0 2.9 3 1 1 4 4 4 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KEZ45783.1 - 0.00078 19.3 0.0 1.2 8.8 0.0 2.5 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.28 KEZ45783.1 - 0.00081 18.4 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S15 PF02129.18 KEZ45783.1 - 0.0073 15.9 0.0 0.22 11.1 0.0 2.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 KEZ45783.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 KEZ45783.1 - 0.022 14.3 0.0 0.28 10.7 0.0 2.2 3 0 0 3 3 3 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KEZ45783.1 - 0.024 13.9 0.0 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ldh_1_C PF02866.18 KEZ45784.1 - 1.6e-44 151.8 0.0 2.6e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KEZ45784.1 - 5e-44 149.8 0.0 7.3e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KEZ45784.1 - 4.5e-06 25.9 0.0 6.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KEZ45784.1 - 0.025 15.0 0.3 0.074 13.5 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain E1-E2_ATPase PF00122.20 KEZ45785.1 - 1.4e-17 63.9 0.0 3.1e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KEZ45785.1 - 6.8e-14 52.6 5.2 1.8e-08 35.0 2.5 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ45785.1 - 0.0065 16.2 0.1 0.08 12.7 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KEZ45785.1 - 0.066 13.3 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Cation transport ATPase (P-type) DUF4059 PF13268.6 KEZ45785.1 - 0.23 11.9 2.8 14 6.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) S6PP PF05116.13 KEZ45785.1 - 0.3 10.6 0.7 11 5.4 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Phage_Gp23 PF10669.9 KEZ45785.1 - 1.7 9.0 7.7 1.3 9.4 3.8 2.6 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DUF3636 PF12331.8 KEZ45787.1 - 5.3e-30 104.2 0.4 1.3e-29 103.0 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF1192 PF06698.11 KEZ45787.1 - 5.7 7.1 7.2 2.5 8.2 2.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) CTP_transf_1 PF01148.20 KEZ45788.1 - 1.1e-77 261.5 26.1 1.3e-77 261.1 26.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family adh_short PF00106.25 KEZ45789.1 - 1.3e-16 60.7 0.0 7.4e-11 41.9 0.0 3.0 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ45789.1 - 8.3e-13 48.4 0.2 5.9e-11 42.4 0.0 2.8 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ45789.1 - 3.2e-05 23.9 0.0 4.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 5_nucleotid_C PF02872.18 KEZ45790.1 - 3.4e-34 118.4 0.0 6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KEZ45790.1 - 8.3e-08 33.0 0.1 1.3e-07 32.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Esterase_phd PF10503.9 KEZ45791.1 - 6.3e-22 78.1 0.2 9.4e-22 77.6 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KEZ45791.1 - 2e-10 40.5 0.4 3.1e-10 39.9 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KEZ45791.1 - 0.0024 17.8 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEZ45791.1 - 0.0051 15.7 0.1 0.009 14.9 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 KEZ45791.1 - 0.039 13.7 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 KEZ45791.1 - 0.088 12.4 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase LIP PF03583.14 KEZ45791.1 - 0.21 10.9 0.9 12 5.1 0.7 2.1 1 1 1 2 2 2 0 Secretory lipase Sulfotransfer_4 PF17784.1 KEZ45792.1 - 3.1e-57 193.9 0.0 3.6e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEZ45792.1 - 2.7e-05 24.6 0.1 9.8e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase family LSM PF01423.22 KEZ45793.1 - 1.5e-13 50.2 0.2 2.1e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KEZ45793.1 - 0.039 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein HNH_2 PF13391.6 KEZ45794.1 - 8e-06 25.9 0.5 2e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 HNH endonuclease HMGL-like PF00682.19 KEZ45795.1 - 5.9e-75 252.2 0.0 1.1e-74 251.4 0.0 1.4 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 KEZ45795.1 - 1.4e-22 80.0 0.0 5.5e-22 78.1 0.0 2.0 2 1 0 2 2 2 1 LeuA allosteric (dimerisation) domain Ank_2 PF12796.7 KEZ45796.1 - 3.3e-49 165.4 0.2 4.4e-14 52.8 0.0 7.8 6 3 2 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45796.1 - 9.5e-37 124.9 5.0 1.6e-06 28.5 0.0 10.9 8 2 4 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45796.1 - 3.2e-33 110.0 9.6 0.0078 16.6 0.0 14.7 15 1 0 15 15 15 7 Ankyrin repeat Ank PF00023.30 KEZ45796.1 - 8.5e-23 79.7 14.0 0.023 15.1 0.0 13.3 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 KEZ45796.1 - 4.7e-18 65.0 7.0 0.017 15.5 0.0 10.6 7 2 4 11 11 11 5 Ankyrin repeats (many copies) MFS_1 PF07690.16 KEZ45797.1 - 2.7e-33 115.4 60.0 2.3e-28 99.1 45.7 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KEZ45797.1 - 0.00012 21.0 0.1 0.00012 21.0 0.1 3.0 3 1 0 3 3 3 1 LacY proton/sugar symporter CbtB PF09489.10 KEZ45797.1 - 2.3 8.4 5.9 4.4 7.5 0.1 4.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Sugar_tr PF00083.24 KEZ45798.1 - 2.1e-79 267.5 23.4 2.5e-79 267.3 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45798.1 - 9.3e-19 67.5 24.7 9.3e-19 67.5 24.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KEZ45799.1 - 1.6e-11 44.1 23.7 5.1e-06 26.5 8.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ45799.1 - 1.6e-09 37.2 0.0 3.7e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sulfatase PF00884.23 KEZ45800.1 - 1.1e-46 159.7 0.5 1.5e-46 159.3 0.5 1.2 1 0 0 1 1 1 1 Sulfatase DUF2330 PF10092.9 KEZ45800.1 - 0.00048 19.3 0.0 0.00076 18.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2330) Ytp1 PF10355.9 KEZ45801.1 - 6.7e-100 333.8 8.8 8.9e-100 333.5 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KEZ45801.1 - 7.1e-09 35.4 0.2 7.1e-09 35.4 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) TMEM107 PF14995.6 KEZ45801.1 - 0.32 11.5 6.6 3.1 8.2 0.6 3.3 3 0 0 3 3 3 0 Transmembrane protein DUF4407 PF14362.6 KEZ45801.1 - 1.5 8.1 4.7 2.9 7.2 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn_clus PF00172.18 KEZ45802.1 - 0.0072 16.4 14.5 0.014 15.5 14.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KEZ45803.1 - 2.5e-13 50.4 0.0 3.3e-09 37.2 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ45803.1 - 4.9e-10 38.8 0.1 0.16 12.6 0.0 6.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 KEZ45803.1 - 1.9e-09 37.6 2.9 0.0002 21.6 0.1 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ45803.1 - 3e-09 37.2 0.7 0.015 15.9 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 KEZ45803.1 - 0.00019 20.8 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 KEZ45803.1 - 0.00022 21.5 0.0 0.00078 19.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ank PF00023.30 KEZ45803.1 - 0.00052 20.4 0.0 4.6 7.9 0.0 4.5 3 1 0 3 3 3 1 Ankyrin repeat NACHT PF05729.12 KEZ45803.1 - 0.0049 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Methyltransf_2 PF00891.18 KEZ45804.1 - 4.6e-18 65.3 0.0 9e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KEZ45804.1 - 0.0085 15.9 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MarR PF01047.22 KEZ45804.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 KEZ45804.1 - 0.076 13.1 0.1 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Dimerisation2 PF16864.5 KEZ45804.1 - 0.078 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain HTH_11 PF08279.12 KEZ45804.1 - 0.081 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain Methyltransf_23 PF13489.6 KEZ45805.1 - 1.8e-24 86.5 0.0 2.8e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45805.1 - 1.2e-14 54.8 0.0 2.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45805.1 - 1.5e-13 51.2 0.0 3.6e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45805.1 - 9.1e-13 48.3 0.1 1.8e-11 44.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45805.1 - 2.4e-10 41.0 0.0 1.5e-09 38.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KEZ45805.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KEZ45805.1 - 0.00028 20.4 0.0 0.00042 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KEZ45805.1 - 0.00032 20.2 0.0 0.00067 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 KEZ45805.1 - 0.0004 19.8 0.0 0.00078 18.8 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KEZ45805.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 KEZ45805.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KEZ45805.1 - 0.087 12.1 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KEZ45805.1 - 0.098 12.0 0.0 0.5 9.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family NACHT PF05729.12 KEZ45806.1 - 0.00052 20.0 0.0 0.004 17.1 0.0 2.2 1 1 0 1 1 1 1 NACHT domain TMF_DNA_bd PF12329.8 KEZ45806.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding SKG6 PF08693.10 KEZ45806.1 - 0.037 13.4 2.0 0.1 12.0 2.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AAA_16 PF13191.6 KEZ45806.1 - 0.046 14.1 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KEZ45806.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF347 PF03988.12 KEZ45806.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF5080 PF16883.5 KEZ45806.1 - 0.22 11.6 0.0 0.39 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5080) Aa_trans PF01490.18 KEZ45809.1 - 1.3e-44 152.5 34.7 1.5e-44 152.4 34.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 KEZ45809.1 - 0.039 13.8 0.6 0.25 11.2 0.6 2.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase GFO_IDH_MocA PF01408.22 KEZ45810.1 - 1.3e-16 61.5 0.0 2.8e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HET PF06985.11 KEZ45811.1 - 2.1e-30 106.0 0.1 3.3e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KEZ45812.1 - 8.1e-11 41.8 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SPOR PF05036.13 KEZ45812.1 - 0.056 13.8 0.0 0.75 10.2 0.0 2.4 2 0 0 2 2 2 0 Sporulation related domain Endonuc_BglI PF14562.6 KEZ45812.1 - 0.19 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI HAV_VP PF12944.7 KEZ45814.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Hepatitis A virus viral protein VP MFS_1 PF07690.16 KEZ45815.1 - 5.6e-33 114.3 23.5 7.7e-33 113.9 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEZ45815.1 - 0.00016 21.5 3.0 0.00037 20.2 3.0 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Neurensin PF14927.6 KEZ45815.1 - 0.27 11.0 2.8 0.37 10.5 0.1 2.5 1 1 1 2 2 2 0 Neurensin SesA PF17107.5 KEZ45816.1 - 2.7e-08 34.1 1.4 3.4e-08 33.7 0.2 1.8 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 KEZ45816.1 - 0.00024 20.5 0.3 0.00044 19.7 0.3 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 KEZ45816.1 - 0.00036 20.5 0.3 0.0038 17.2 0.0 2.7 2 2 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KEZ45816.1 - 0.00088 19.6 0.4 0.0085 16.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 KEZ45816.1 - 0.0016 18.2 0.0 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ45816.1 - 0.002 18.5 1.3 0.008 16.6 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain NB-ARC PF00931.22 KEZ45816.1 - 0.0086 15.3 0.0 0.043 13.0 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 KEZ45816.1 - 0.052 14.1 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Jnk-SapK_ap_N PF09744.9 KEZ45816.1 - 0.057 13.6 3.9 0.076 13.2 1.6 2.3 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 AAA_18 PF13238.6 KEZ45816.1 - 0.059 13.9 0.0 0.59 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ45816.1 - 0.078 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KEZ45816.1 - 0.12 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KEZ45816.1 - 0.13 12.7 2.7 0.9 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain zf-TFIIB PF13453.6 KEZ45816.1 - 0.14 11.5 1.1 2 7.8 0.1 2.9 2 0 0 2 2 2 0 Transcription factor zinc-finger Gene66 PF02053.15 KEZ45816.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Gene 66 (IR5) protein Vpu PF00558.19 KEZ45816.1 - 0.21 11.4 1.6 0.7 9.7 1.6 1.8 1 0 0 1 1 1 0 Vpu protein APG17 PF04108.12 KEZ45816.1 - 0.49 9.4 4.1 2.5 7.1 4.1 1.9 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF4246 PF14033.6 KEZ45817.1 - 1.6e-98 330.8 0.1 1.1e-96 324.7 0.1 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) Fungal_trans PF04082.18 KEZ45818.1 - 2e-14 53.3 0.1 3.8e-14 52.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45818.1 - 1.4e-13 50.7 27.4 2.8e-08 33.8 7.0 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KEZ45819.1 - 4.6e-73 246.6 17.1 7.3e-72 242.7 11.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter Ion_trans PF00520.31 KEZ45820.1 - 0.0041 16.4 16.8 0.0081 15.4 16.8 1.5 1 0 0 1 1 1 1 Ion transport protein HET PF06985.11 KEZ45821.1 - 4.5e-23 82.2 0.2 1.1e-22 80.9 0.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KEZ45823.1 - 0.5 10.5 2.4 0.39 10.9 0.6 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KEZ45824.1 - 1.9e-34 119.1 28.8 2.9e-34 118.6 28.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ammonium_transp PF00909.21 KEZ45825.1 - 5.3e-99 331.6 15.8 6.5e-99 331.3 15.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SepZ PF06066.11 KEZ45825.1 - 0.19 12.0 1.0 0.59 10.4 1.0 1.8 1 0 0 1 1 1 0 SepZ Ank_2 PF12796.7 KEZ45826.1 - 2.6e-57 191.4 0.0 4.9e-14 52.7 0.1 8.3 5 3 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ45826.1 - 5.3e-43 144.5 19.0 2e-05 24.8 0.8 11.6 8 3 4 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45826.1 - 3.1e-39 128.5 3.2 0.003 17.9 0.0 14.5 14 0 0 14 14 14 8 Ankyrin repeat Ank PF00023.30 KEZ45826.1 - 1.3e-37 126.6 7.9 0.013 15.9 0.9 13.1 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.6 KEZ45826.1 - 2.2e-36 123.8 4.9 9.9e-06 26.0 0.1 10.1 7 2 2 10 10 10 8 Ankyrin repeats (many copies) SBP_bac_11 PF13531.6 KEZ45826.1 - 0.046 13.5 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein HET PF06985.11 KEZ45826.1 - 0.14 12.5 0.0 4.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Fascin PF06268.13 KEZ45826.1 - 0.16 12.2 0.2 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Fascin domain Transferase PF02458.15 KEZ45829.1 - 1.3e-23 83.4 0.0 2.7e-23 82.3 0.0 1.3 1 1 0 1 1 1 1 Transferase family TMF_DNA_bd PF12329.8 KEZ45831.1 - 0.016 15.2 0.3 0.048 13.7 0.3 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF5082 PF16888.5 KEZ45831.1 - 0.025 14.8 0.6 0.049 13.9 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SKA2 PF16740.5 KEZ45831.1 - 0.14 12.0 4.1 1 9.1 1.5 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 AAA_11 PF13086.6 KEZ45831.1 - 0.17 11.6 1.4 0.27 11.0 1.4 1.2 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 KEZ45831.1 - 0.41 10.7 4.9 0.1 12.7 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KEZ45831.1 - 0.44 10.7 2.8 0.33 11.1 0.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 KEZ45831.1 - 0.51 9.9 5.7 1 8.9 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Laminin_II PF06009.12 KEZ45831.1 - 1.4 8.9 5.7 1 9.4 2.5 2.3 1 1 0 2 2 2 0 Laminin Domain II Glyco_hydro_1 PF00232.18 KEZ45832.1 - 8.6e-133 443.1 0.0 1.3e-132 442.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HET PF06985.11 KEZ45832.1 - 3e-53 180.1 0.4 6.9e-28 97.8 0.0 3.4 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 KEZ45833.1 - 5.5e-77 259.5 23.8 6.6e-77 259.3 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45833.1 - 3.4e-20 72.3 45.1 1.4e-17 63.6 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KEZ45833.1 - 6.3 5.0 18.3 0.19 10.0 0.4 3.8 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 KEZ45834.1 - 4.2e-11 42.4 0.5 6.4e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45834.1 - 0.00044 20.3 12.7 0.00085 19.4 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3237 PF11578.8 KEZ45836.1 - 2.4e-27 95.6 0.2 2.7e-27 95.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) SesA PF17107.5 KEZ45837.1 - 0.0077 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Acyl-CoA_dh_2 PF08028.11 KEZ45838.1 - 1.2e-13 51.5 0.0 2.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KEZ45838.1 - 0.00059 20.0 0.1 0.0017 18.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KEZ45838.1 - 0.00089 19.9 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KEZ45838.1 - 0.0022 18.2 0.0 0.0065 16.7 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ADH_zinc_N PF00107.26 KEZ45839.1 - 2.3e-07 30.8 0.3 4.1e-07 30.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ45839.1 - 0.0003 20.6 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KEZ45839.1 - 0.18 11.7 0.0 0.59 10.0 0.0 1.9 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase p450 PF00067.22 KEZ45841.1 - 4.8e-60 203.6 0.0 6.7e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KEZ45842.1 - 5.2e-09 35.8 0.0 0.0012 18.2 0.0 2.8 2 2 0 2 2 2 2 Protein kinase domain APH PF01636.23 KEZ45843.1 - 1.2e-19 71.2 0.0 1.6e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KEZ45843.1 - 3.1e-06 26.9 0.0 5.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KEZ45843.1 - 2.5e-05 24.0 0.0 0.058 13.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.14 KEZ45843.1 - 0.0037 16.6 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Defensin_2 PF01097.18 KEZ45844.1 - 2.4e-08 33.8 9.5 3.5e-08 33.2 9.5 1.3 1 0 0 1 1 1 1 Arthropod defensin Toxin_38 PF14866.6 KEZ45844.1 - 0.26 11.6 11.8 0.45 10.9 11.8 1.4 1 1 0 1 1 1 0 Potassium channel toxin YbgS PF13985.6 KEZ45844.1 - 5.8 7.2 5.1 3.2 8.1 2.2 1.8 1 1 1 2 2 2 0 YbgS-like protein DJ-1_PfpI PF01965.24 KEZ45845.1 - 3.3e-08 33.5 0.0 5.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Tymo_coat PF00983.18 KEZ45845.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Tymovirus coat protein Mitofilin PF09731.9 KEZ45848.1 - 1.8e-09 37.1 0.0 2.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Dus PF01207.17 KEZ45849.1 - 0.046 12.8 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Glycogen_syn PF05693.13 KEZ45850.1 - 5.2e-208 692.6 0.0 5.8e-208 692.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KEZ45850.1 - 8.8e-07 28.6 0.0 0.00022 20.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ45850.1 - 5.1e-05 23.7 0.0 0.0062 17.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ45850.1 - 0.0006 20.3 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KEZ45850.1 - 0.036 14.1 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Imm-NTF2 PF15655.6 KEZ45850.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 NTF2 fold immunity protein Hemerythrin PF01814.23 KEZ45851.1 - 4.5e-12 46.7 1.9 6.7e-12 46.2 1.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain adh_short_C2 PF13561.6 KEZ45852.1 - 1.1e-42 146.3 0.0 4.8e-42 144.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ45852.1 - 7e-41 139.8 0.1 1.1e-40 139.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KEZ45852.1 - 1.6e-06 28.1 0.2 4.9e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 KEZ45852.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KEZ45852.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KEZ45852.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KEZ45852.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CHZ PF09649.10 KEZ45853.1 - 0.041 13.4 0.1 0.086 12.3 0.1 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ Amino_oxidase PF01593.24 KEZ45854.1 - 2.5e-50 172.1 0.1 2.9e-50 171.9 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KEZ45854.1 - 3.5e-12 46.4 0.2 7.7e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ45854.1 - 8.9e-07 28.8 0.1 2.6e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KEZ45854.1 - 1.1e-05 24.8 0.3 1.8e-05 24.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ45854.1 - 2.9e-05 23.5 0.0 6.7e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KEZ45854.1 - 0.00011 21.1 0.0 0.00016 20.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KEZ45854.1 - 0.00029 20.3 0.1 0.00049 19.6 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ45854.1 - 0.0004 19.7 0.2 0.0007 18.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KEZ45854.1 - 0.0032 16.8 0.6 0.0086 15.4 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 KEZ45854.1 - 0.0041 16.2 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KEZ45854.1 - 0.0044 17.5 0.1 0.0095 16.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ45854.1 - 0.0062 15.6 0.2 0.01 14.9 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEZ45854.1 - 0.064 12.5 0.2 0.82 8.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4082 PF13313.6 KEZ45854.1 - 0.08 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Fungal_trans PF04082.18 KEZ45855.1 - 1.5e-12 47.2 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45855.1 - 9.5e-08 32.0 8.0 2e-07 31.0 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asparaginase_2 PF01112.18 KEZ45855.1 - 0.037 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Asparaginase p450 PF00067.22 KEZ45856.1 - 2.2e-37 128.9 0.0 2.2e-33 115.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 MciZ PF13072.6 KEZ45856.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ HgmA PF04209.13 KEZ45857.1 - 3.1e-174 579.6 0.3 7.6e-115 384.0 0.4 2.2 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Beta-lactamase PF00144.24 KEZ45858.1 - 4.7e-45 154.3 0.4 6.1e-45 153.9 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase VbhA PF18495.1 KEZ45858.1 - 0.054 13.4 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Antitoxin VbhA Beta-lactamase2 PF13354.6 KEZ45858.1 - 0.06 12.9 0.0 0.4 10.2 0.0 2.2 2 1 0 2 2 2 0 Beta-lactamase enzyme family zf-C2H2_4 PF13894.6 KEZ45859.1 - 0.0029 18.3 0.4 0.0073 17.1 0.4 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KEZ45859.1 - 0.014 15.1 0.4 0.028 14.2 0.4 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 KEZ45859.1 - 0.064 13.7 0.5 0.064 13.7 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KEZ45859.1 - 0.081 13.4 0.3 0.18 12.3 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type MFS_1 PF07690.16 KEZ45860.1 - 1.5e-30 106.4 48.1 1.5e-30 106.4 48.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ45860.1 - 1.5e-13 50.0 11.9 2.3e-13 49.5 11.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5453 PF17534.2 KEZ45860.1 - 0.5 10.3 3.5 8.6 6.3 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5453) DUF4440 PF14534.6 KEZ45861.1 - 0.034 14.6 0.1 0.065 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Phage_T4_Gp30_7 PF06919.11 KEZ45861.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Phage Gp30.7 protein adh_short PF00106.25 KEZ45862.1 - 1.5e-14 53.9 0.0 2.7e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ45862.1 - 7.6e-07 28.9 0.0 0.00058 19.5 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ45862.1 - 0.00028 20.8 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ45862.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KEZ45862.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KEZ45862.1 - 0.044 13.9 0.0 0.39 10.8 0.0 2.2 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_11 PF00457.17 KEZ45863.1 - 2.5e-69 232.4 11.6 2.9e-69 232.3 11.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Fungal_trans PF04082.18 KEZ45864.1 - 2.9e-16 59.3 0.0 5.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KEZ45864.1 - 3.2e-05 24.2 12.2 0.024 15.1 5.2 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KEZ45864.1 - 0.0003 20.8 11.7 0.0003 20.8 11.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KEZ45864.1 - 0.0066 17.2 4.5 0.0066 17.2 4.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KEZ45864.1 - 0.015 15.6 1.8 0.066 13.6 1.8 2.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KEZ45864.1 - 0.02 14.9 9.1 0.07 13.2 0.1 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEZ45864.1 - 0.03 14.8 9.5 1.5 9.4 1.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KEZ45864.1 - 0.037 14.3 4.0 0.37 11.2 1.8 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ADH_N PF08240.12 KEZ45865.1 - 2.1e-22 79.0 0.1 4.3e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ45865.1 - 4.6e-18 65.5 0.1 1.1e-17 64.2 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ45865.1 - 1.2e-08 34.7 0.3 2.1e-08 33.9 0.3 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KEZ45865.1 - 0.019 14.3 1.6 0.035 13.4 1.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KEZ45865.1 - 0.031 13.6 1.8 4 6.8 0.3 2.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.22 KEZ45866.1 - 3.3e-70 237.1 0.0 4e-69 233.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 KEZ45867.1 - 9.8e-38 130.0 0.0 5e-33 114.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ45867.1 - 4.3e-08 33.6 0.0 6.7e-07 29.8 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_7 PF13508.7 KEZ45868.1 - 1.4e-07 31.8 0.0 2.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KEZ45868.1 - 2.1e-07 31.0 0.0 3.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ45868.1 - 1.8e-05 24.9 0.0 2.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KEZ45868.1 - 0.0025 17.9 0.0 0.0086 16.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ45868.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KEZ45868.1 - 0.075 13.2 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 KEZ45869.1 - 2e-30 106.0 31.1 2e-30 106.0 31.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.21 KEZ45870.1 - 2.5e-10 40.2 0.0 6.7e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KEZ45870.1 - 1.6e-08 33.9 0.0 2.5e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KEZ45870.1 - 1.3e-07 31.7 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KEZ45870.1 - 3e-07 29.9 0.1 5.5e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KEZ45870.1 - 5.8e-07 29.2 0.1 1.9e-06 27.5 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KEZ45870.1 - 7.4e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NmrA PF05368.13 KEZ45871.1 - 1.2e-55 188.6 0.0 1.4e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ45871.1 - 3.1e-16 59.8 0.0 4.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ45871.1 - 9.6e-07 28.1 0.0 1.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KEZ45871.1 - 0.00035 20.8 0.0 0.0006 20.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KEZ45871.1 - 0.00064 19.3 0.0 0.0017 17.8 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEZ45871.1 - 0.0039 17.4 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 KEZ45871.1 - 0.032 14.7 0.1 0.073 13.5 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_61 PF03443.14 KEZ45872.1 - 1.1e-63 214.9 0.0 1.3e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KEZ45873.1 - 2.8e-52 177.7 0.0 3.6e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 H_lectin PF09458.10 KEZ45873.1 - 0.085 13.1 0.3 0.2 11.9 0.3 1.6 1 0 0 1 1 1 0 H-type lectin domain Abhydrolase_4 PF08386.10 KEZ45874.1 - 4.5e-19 68.5 0.0 8.3e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEZ45874.1 - 3.4e-18 66.2 0.0 2.5e-07 30.6 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Transferase PF02458.15 KEZ45875.1 - 1e-08 34.3 0.0 2.5e-07 29.7 0.0 2.5 2 1 0 2 2 2 1 Transferase family Glyco_hydro_16 PF00722.21 KEZ45876.1 - 7.5e-20 71.1 0.3 2.1e-19 69.7 0.2 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 ATPase_gene1 PF09527.10 KEZ45876.1 - 0.097 12.8 0.2 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Glyco_trans_2_3 PF13632.6 KEZ45877.1 - 3.3e-52 177.3 3.1 3.3e-52 177.3 3.1 3.2 3 1 1 4 4 4 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KEZ45877.1 - 0.0013 18.2 0.1 0.0037 16.7 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEZ45877.1 - 0.0018 18.1 0.0 0.0051 16.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 RTA1 PF04479.13 KEZ45878.1 - 6.6e-55 185.9 4.5 9.1e-55 185.5 4.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_43 PF04616.14 KEZ45879.1 - 8.9e-20 71.2 0.9 1.1e-19 70.8 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cu_bind_like PF02298.17 KEZ45880.1 - 0.22 11.6 0.1 0.8 9.8 0.1 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain Methyltransf_23 PF13489.6 KEZ45881.1 - 5.5e-18 65.4 0.0 8e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ45881.1 - 3.3e-12 46.9 0.0 1.1e-11 45.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ45881.1 - 2.1e-11 44.3 0.0 4.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ45881.1 - 6.5e-10 39.6 0.0 4.4e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ45881.1 - 7.1e-07 29.1 0.0 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ45881.1 - 4.1e-05 23.0 0.0 0.056 12.8 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KEZ45881.1 - 0.0028 17.0 0.0 0.03 13.6 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KEZ45881.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ45881.1 - 0.039 13.4 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KEZ45881.1 - 0.062 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KEZ45881.1 - 0.064 12.6 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_M3 PF01432.20 KEZ45882.1 - 1.2e-95 321.4 0.0 1.8e-95 320.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 CorA PF01544.18 KEZ45884.1 - 7.5e-07 28.8 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Tricorn_C1 PF14684.6 KEZ45884.1 - 0.27 11.4 2.9 0.96 9.6 0.4 3.0 3 0 0 3 3 3 0 Tricorn protease C1 domain EI24 PF07264.11 KEZ45885.1 - 0.82 9.9 10.0 1.2 9.4 10.0 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2569 PF10754.9 KEZ45885.1 - 9.7 6.6 12.1 15 6.0 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) MFS_1 PF07690.16 KEZ45886.1 - 4.2e-21 75.3 56.7 9.6e-16 57.6 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1290 PF06947.12 KEZ45886.1 - 0.067 13.3 3.5 2.5 8.2 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1290) CPP1-like PF11833.8 KEZ45886.1 - 0.91 9.2 4.4 2.7 7.6 4.4 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Kinesin PF00225.23 KEZ45887.1 - 4.1e-116 387.5 0.0 6.4e-116 386.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ45887.1 - 6.1e-27 94.4 0.0 1.4e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 KEZ45887.1 - 0.021 15.0 6.8 0.06 13.6 6.8 1.7 1 1 0 1 1 1 0 Herpesvirus UL14-like protein DUF932 PF06067.11 KEZ45887.1 - 0.038 13.8 3.3 0.085 12.6 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF3584 PF12128.8 KEZ45887.1 - 0.15 9.6 15.8 0.2 9.1 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zn_clus PF00172.18 KEZ45888.1 - 1.6e-07 31.3 7.1 2.4e-07 30.8 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KEZ45888.1 - 0.5 10.3 7.7 0.6 10.0 7.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_16 PF13191.6 KEZ45889.1 - 3.2e-06 27.6 0.1 1.2e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KEZ45889.1 - 4.3e-06 26.8 0.3 0.00011 22.2 0.3 2.6 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 KEZ45889.1 - 0.012 16.1 0.1 0.13 12.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KEZ45889.1 - 0.053 14.1 0.0 0.17 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ45889.1 - 0.068 13.4 0.0 0.26 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain SesA PF17107.5 KEZ45889.1 - 0.068 13.4 0.0 0.84 9.8 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ATPase_2 PF01637.18 KEZ45889.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KEZ45889.1 - 0.082 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain CGI-121 PF08617.10 KEZ45890.1 - 1.3e-50 171.7 0.0 1.5e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pro_dh PF01619.18 KEZ45891.1 - 8.8e-71 238.8 0.0 1e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase NIF PF03031.18 KEZ45892.1 - 3.2e-38 131.0 0.0 4.7e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase D123 PF07065.14 KEZ45892.1 - 0.31 10.2 2.7 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 D123 EMC3_TMCO1 PF01956.16 KEZ45892.1 - 0.77 9.5 5.5 1.5 8.5 5.5 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RNase_PH PF01138.21 KEZ45893.1 - 1.7e-36 125.6 0.6 4.8e-36 124.2 0.2 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.20 KEZ45894.1 - 3.5e-32 110.4 0.2 3.9e-27 94.3 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 KEZ45894.1 - 5.5e-10 39.1 0.1 1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KEZ45894.1 - 5.9e-07 29.9 0.4 0.022 15.2 0.1 2.6 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KEZ45894.1 - 0.00024 21.4 0.0 1.1 9.7 0.0 3.9 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KEZ45894.1 - 0.0056 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family QSOX_Trx1 PF18108.1 KEZ45894.1 - 0.0097 16.1 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 1 QSOX Trx-like domain TraF PF13728.6 KEZ45894.1 - 0.012 15.5 0.0 0.012 15.5 0.0 4.0 3 1 1 4 4 4 0 F plasmid transfer operon protein HTH_6 PF01418.17 KEZ45894.1 - 0.11 12.5 0.0 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family ERp29_N PF07912.13 KEZ45894.1 - 0.12 12.5 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 ERp29, N-terminal domain Vta1 PF04652.16 KEZ45895.1 - 5.4e-31 107.5 3.2 5.4e-31 107.5 3.2 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KEZ45895.1 - 3.7e-17 61.7 0.1 3.7e-17 61.7 0.1 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain DUF1996 PF09362.10 KEZ45896.1 - 5.5e-83 278.5 0.2 6.8e-83 278.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Bax1-I PF01027.20 KEZ45897.1 - 7e-37 127.3 7.6 1e-36 126.7 7.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 COX14 PF14880.6 KEZ45897.1 - 0.12 12.2 0.9 31 4.5 0.0 3.3 3 0 0 3 3 3 0 Cytochrome oxidase c assembly PMSR PF01625.21 KEZ45898.1 - 2.8e-60 202.9 0.0 3.3e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Sugar_tr PF00083.24 KEZ45899.1 - 9.5e-82 275.2 14.9 1.1e-81 275.0 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ45899.1 - 8.8e-30 103.8 23.3 8.8e-30 103.8 23.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KEZ45899.1 - 3.6e-05 22.4 0.9 3.6e-05 22.4 0.9 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KEZ45899.1 - 9.4e-05 21.1 19.6 0.0047 15.5 3.6 3.4 2 1 1 3 3 3 2 MFS/sugar transport protein AA_permease_C PF13906.6 KEZ45899.1 - 0.019 15.0 1.2 0.07 13.2 1.2 2.0 1 0 0 1 1 1 0 C-terminus of AA_permease MIP PF00230.20 KEZ45900.1 - 6.5e-48 163.4 20.4 8.3e-48 163.1 20.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3328 PF11807.8 KEZ45901.1 - 3.7e-50 170.7 1.4 4.7e-50 170.4 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.18 KEZ45902.1 - 4e-16 58.8 0.0 7.3e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ45902.1 - 2.5e-09 37.1 12.4 4.1e-09 36.4 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 KEZ45903.1 - 2e-06 27.9 0.0 4.8e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Ribosomal_S21e PF01249.18 KEZ45904.1 - 2.1e-40 136.7 0.1 2.4e-40 136.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Forkhead PF00250.18 KEZ45905.1 - 8e-17 61.3 0.2 2.1e-16 59.9 0.2 1.6 1 1 0 1 1 1 1 Forkhead domain Nup84_Nup100 PF04121.13 KEZ45905.1 - 0.084 11.0 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 CactinC_cactus PF09732.9 KEZ45906.1 - 7.6e-58 193.9 5.2 1.3e-57 193.2 5.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KEZ45906.1 - 1.5e-56 191.3 11.5 2.1e-56 190.8 11.5 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin SF3A2 PF16835.5 KEZ45906.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 KEZ45906.1 - 0.21 11.6 1.8 0.41 10.7 0.3 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF3069 PF11269.8 KEZ45906.1 - 0.38 11.0 3.7 0.14 12.4 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) Glyco_hydro_3_C PF01915.22 KEZ45907.1 - 9.7e-43 146.5 0.2 2.8e-42 145.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KEZ45907.1 - 1.8e-28 99.8 0.0 3e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KEZ45907.1 - 5.1e-08 32.9 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Mannosyl_trans3 PF11051.8 KEZ45909.1 - 9.4e-36 123.6 0.0 2.1e-25 89.6 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Syja_N PF02383.18 KEZ45910.1 - 3e-87 292.9 0.0 3.8e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 KEZ45911.1 - 2.8e-58 196.1 0.1 3.6e-58 195.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ45911.1 - 5.5e-36 123.4 0.1 1.1e-35 122.4 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ45911.1 - 1.7e-14 53.6 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEZ45911.1 - 1.5e-06 27.8 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEZ45911.1 - 5e-06 26.6 0.0 7.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KEZ45911.1 - 6.1e-06 25.9 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KEZ45911.1 - 1.3e-05 25.1 0.5 0.077 12.9 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KEZ45911.1 - 0.025 15.0 0.3 0.054 13.9 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 KEZ45911.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KEZ45911.1 - 0.13 11.4 0.1 0.57 9.3 0.1 2.1 1 1 0 1 1 1 0 G-protein alpha subunit GbpA_2 PF18416.1 KEZ45911.1 - 0.17 12.2 0.8 5.6 7.3 0.0 2.3 1 1 1 2 2 2 0 N-acetylglucosamine binding protein domain 2 Mitofilin PF09731.9 KEZ45912.1 - 5.7e-143 478.0 28.7 2.1e-140 469.5 28.7 2.1 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF1848 PF08902.11 KEZ45912.1 - 0.0026 17.5 2.8 0.1 12.3 2.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1848) Serine_rich PF08824.10 KEZ45912.1 - 0.2 11.7 11.9 3.9 7.5 0.1 2.8 3 0 0 3 3 3 0 Serine rich protein interaction domain WXG100 PF06013.12 KEZ45912.1 - 0.26 11.5 8.4 0.13 12.5 1.2 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG KxDL PF10241.9 KEZ45912.1 - 4.3 7.7 8.1 0.68 10.3 0.4 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Mur_ligase_M PF08245.12 KEZ45913.1 - 3.6e-08 33.6 0.0 1.5e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Mur ligase middle domain adh_short PF00106.25 KEZ45914.1 - 3.8e-38 130.9 0.1 4.6e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ45914.1 - 7.7e-29 100.9 0.1 9.6e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ45914.1 - 6.9e-09 35.9 0.2 1.8e-08 34.5 0.2 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KEZ45914.1 - 0.00036 19.6 0.0 0.0059 15.6 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEZ45914.1 - 0.0028 17.2 0.2 0.0077 15.7 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KEZ45914.1 - 0.031 14.5 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Asp_protease_2 PF13650.6 KEZ45915.1 - 5.7e-09 36.5 0.2 1.5e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KEZ45915.1 - 2.6e-06 27.9 0.0 0.00059 20.4 0.0 2.8 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KEZ45915.1 - 7e-05 22.6 0.1 0.042 13.6 0.0 2.5 3 0 0 3 3 3 2 Aspartyl protease zf-H2C2_2 PF13465.6 KEZ45915.1 - 0.2 12.2 4.9 7.1 7.2 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 KEZ45915.1 - 0.26 11.8 0.3 0.26 11.8 0.3 4.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF3623 PF12291.8 KEZ45916.1 - 0.025 13.8 1.9 0.035 13.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) DUF1304 PF06993.12 KEZ45916.1 - 0.044 13.8 4.9 0.61 10.1 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) Ras PF00071.22 KEZ45917.1 - 1.7e-42 144.8 0.0 4.3e-42 143.5 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KEZ45917.1 - 3.7e-30 104.6 0.0 5.7e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ45917.1 - 8.1e-11 41.7 0.0 2.3e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEZ45917.1 - 8.1e-05 22.1 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KEZ45917.1 - 0.0002 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KEZ45917.1 - 0.0062 16.7 0.0 0.0097 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KEZ45917.1 - 0.0082 15.7 0.0 0.054 13.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KEZ45917.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KEZ45917.1 - 0.011 15.5 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 KEZ45917.1 - 0.034 14.6 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 KEZ45917.1 - 0.037 13.9 0.1 0.34 10.8 0.0 2.1 1 1 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 KEZ45917.1 - 0.048 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KEZ45917.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ45917.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KEZ45917.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KEZ45917.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Mannosidase_ig PF17786.1 KEZ45918.1 - 1.9e-13 50.8 1.0 5.7e-13 49.3 0.1 2.2 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KEZ45918.1 - 9.2e-12 45.6 1.2 1.5e-11 44.9 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KEZ45918.1 - 0.00034 20.3 0.2 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KEZ45918.1 - 0.0065 16.4 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KEZ45918.1 - 0.0087 15.2 0.3 0.033 13.3 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cytotoxic PF09000.10 KEZ45918.1 - 0.1 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Cytotoxic Cadherin-like PF12733.7 KEZ45918.1 - 0.19 12.2 4.2 1.2 9.7 0.7 3.2 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain Ribosomal_L14 PF00238.19 KEZ45919.1 - 9.7e-33 112.8 0.0 1.2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF5427 PF10310.9 KEZ45921.1 - 5.7e-168 559.7 0.2 6.8e-168 559.4 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) BST2 PF16716.5 KEZ45921.1 - 0.53 10.9 3.7 17 6.1 0.5 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Ndc1_Nup PF09531.10 KEZ45921.1 - 1.5 7.4 3.8 2.1 6.9 3.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_1 PF00515.28 KEZ45922.1 - 6.4e-41 136.6 20.8 2e-05 24.2 0.2 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat STI1 PF17830.1 KEZ45922.1 - 2.9e-37 126.4 10.1 6.1e-20 70.9 0.6 3.3 4 0 0 4 4 3 2 STI1 domain TPR_2 PF07719.17 KEZ45922.1 - 3.4e-35 117.3 22.9 0.00015 21.6 0.2 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ45922.1 - 3.4e-19 68.2 23.5 0.00024 20.7 0.4 8.0 9 0 0 9 9 9 5 TPR repeat TPR_8 PF13181.6 KEZ45922.1 - 9.5e-17 59.8 13.4 0.0094 16.1 0.0 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ45922.1 - 7.6e-15 55.0 15.7 1.1e-08 35.2 0.0 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ45922.1 - 2.2e-14 53.8 15.7 2.9e-05 24.6 0.3 6.9 5 2 3 8 8 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ45922.1 - 5.1e-14 52.2 4.0 0.0006 19.9 0.0 6.1 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ45922.1 - 7.9e-14 50.6 3.1 0.093 12.8 0.0 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ45922.1 - 1.4e-13 50.4 11.1 0.49 11.4 0.1 9.1 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ45922.1 - 5.6e-13 49.2 6.9 0.013 16.0 0.0 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ45922.1 - 2.7e-10 39.9 12.8 0.62 10.6 0.2 8.4 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ45922.1 - 4.1e-07 29.7 11.3 0.26 11.2 0.1 7.3 6 1 1 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.8 KEZ45922.1 - 0.00061 18.8 0.2 0.00061 18.8 0.2 3.8 2 1 0 4 4 4 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 KEZ45922.1 - 0.0035 17.9 15.1 19 6.2 0.0 7.7 8 0 0 8 8 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEZ45922.1 - 0.007 16.4 5.5 2.4 8.3 0.0 5.0 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KEZ45922.1 - 0.033 14.4 9.5 0.076 13.3 0.8 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF5486 PF17588.2 KEZ45922.1 - 0.11 12.3 4.9 1.4 8.9 1.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5486) CODH_A_N PF18537.1 KEZ45922.1 - 0.12 12.4 0.0 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Trypan_PARP PF05887.11 KEZ45922.1 - 0.87 9.6 12.8 2.7 8.0 12.8 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EMP24_GP25L PF01105.24 KEZ45922.1 - 0.92 9.4 3.6 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD LIN37 PF15306.6 KEZ45922.1 - 0.96 9.7 5.2 0.61 10.3 2.4 2.0 2 0 0 2 2 2 0 LIN37 TPR_20 PF14561.6 KEZ45922.1 - 2.3 8.6 11.0 2.1 8.8 0.3 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPM_phosphatase PF04536.14 KEZ45922.1 - 5.6 7.2 6.8 61 3.8 0.0 4.0 4 1 0 4 4 4 0 TPM domain DUF3391 PF11871.8 KEZ45922.1 - 5.6 7.5 11.7 0.084 13.4 0.7 2.9 2 1 0 2 2 1 0 Domain of unknown function (DUF3391) RNA_pol_Rpc34 PF05158.12 KEZ45924.1 - 6.9e-92 308.4 0.0 9.8e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KEZ45924.1 - 0.00029 21.4 0.1 0.49 11.1 0.0 2.9 3 0 0 3 3 3 2 Replication protein A C terminal Rhodanese PF00581.20 KEZ45925.1 - 2.8e-06 27.8 0.1 5.1e-06 27.0 0.1 1.4 1 1 0 1 1 1 1 Rhodanese-like domain LSM PF01423.22 KEZ45926.1 - 8.7e-21 73.4 0.5 9.7e-21 73.2 0.5 1.0 1 0 0 1 1 1 1 LSM domain FAM76 PF16046.5 KEZ45927.1 - 0.021 14.2 0.7 0.021 14.2 0.7 2.5 3 0 0 3 3 3 0 FAM76 protein DUF3844 PF12955.7 KEZ45928.1 - 3.8e-34 117.0 1.3 7.5e-34 116.0 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Pkinase PF00069.25 KEZ45929.1 - 1.2e-20 74.0 0.0 7.9e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45929.1 - 3.8e-14 52.6 0.0 2.8e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Cation_ATPase_C PF00689.21 KEZ45931.1 - 1.1e-44 152.4 10.7 1.1e-44 152.4 10.7 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEZ45931.1 - 3.6e-34 117.9 0.5 3.6e-34 117.9 0.5 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KEZ45931.1 - 3.2e-21 75.2 0.1 6.6e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ45931.1 - 1.7e-15 57.9 1.8 1.6e-14 54.7 1.8 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ45931.1 - 5.6e-09 35.5 0.2 6.4e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KEZ45931.1 - 0.0004 20.2 0.1 0.0008 19.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4512 PF14975.6 KEZ45932.1 - 5.1 8.0 5.9 3.7 8.4 3.6 2.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4512) ADH_N PF08240.12 KEZ45933.1 - 1.5e-30 105.3 1.4 2.5e-30 104.6 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ45933.1 - 1.4e-24 86.6 0.2 2.2e-24 85.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ45933.1 - 6e-09 35.7 0.3 9.3e-09 35.1 0.3 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KEZ45933.1 - 3e-06 28.3 0.0 7.5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KEZ45933.1 - 1.1e-05 24.9 2.1 1.8e-05 24.2 2.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KEZ45933.1 - 0.0052 16.1 0.1 0.0085 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.6 KEZ45933.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KEZ45933.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KEZ45933.1 - 0.023 15.4 0.1 0.063 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KEZ45933.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KEZ45933.1 - 0.098 11.3 0.7 0.13 10.9 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KEZ45933.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Met_10 PF02475.16 KEZ45933.1 - 0.16 11.7 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Atg14 PF10186.9 KEZ45935.1 - 1.7e-13 50.4 7.9 1.1e-11 44.5 7.9 2.2 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KEZ45935.1 - 6.3e-13 48.4 0.0 2.6e-08 33.2 0.0 3.8 3 1 0 3 3 3 3 Vacuolar protein sorting 38 ATG16 PF08614.11 KEZ45935.1 - 0.042 14.1 8.2 0.075 13.3 8.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KEZ45935.1 - 0.066 13.3 4.8 0.18 11.9 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 KEZ45935.1 - 0.085 12.4 4.6 0.13 11.8 4.6 1.2 1 0 0 1 1 1 0 Intermediate filament protein CDPS PF16715.5 KEZ45935.1 - 0.19 11.4 2.0 17 5.0 0.0 2.3 2 0 0 2 2 2 0 Cyclodipeptide synthase Spc7 PF08317.11 KEZ45935.1 - 0.24 10.2 4.7 0.38 9.6 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 KEZ45935.1 - 1.3 9.5 10.2 1.8 9.0 4.5 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Lipase_GDSL_2 PF13472.6 KEZ45936.1 - 3.5e-20 73.1 1.7 7.9e-20 72.0 1.7 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 KEZ45936.1 - 7.8e-09 36.0 11.3 0.0016 19.2 1.8 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Lipase_GDSL PF00657.22 KEZ45936.1 - 5e-08 33.2 0.1 1.1e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ANAPC4_WD40 PF12894.7 KEZ45936.1 - 0.0024 18.1 0.3 1.6 9.1 0.1 3.9 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Alpha_adaptinC2 PF02883.20 KEZ45936.1 - 2.9 8.3 3.9 20 5.6 0.2 2.9 3 0 0 3 3 3 0 Adaptin C-terminal domain Pkinase PF00069.25 KEZ45937.1 - 6.3e-64 215.9 0.0 1.1e-63 215.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45937.1 - 6.6e-35 120.6 0.0 5.1e-29 101.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KEZ45937.1 - 3.5e-07 29.8 0.0 0.00076 18.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KEZ45937.1 - 0.0025 17.8 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEZ45937.1 - 0.025 13.5 0.2 0.039 12.9 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KEZ45937.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ45937.1 - 0.21 10.3 0.1 0.57 8.9 0.1 1.7 1 0 0 1 1 1 0 Fungal protein kinase TMEM100 PF16311.5 KEZ45938.1 - 0.023 14.3 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 CorA PF01544.18 KEZ45938.1 - 0.081 12.2 1.8 0.2 10.9 1.8 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 KEZ45939.1 - 3.6e-21 75.7 0.0 1.7e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45939.1 - 7.2e-10 38.6 1.3 0.0031 16.8 0.1 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 KEZ45939.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Na_Ca_ex PF01699.24 KEZ45940.1 - 2e-33 115.5 26.8 1.7e-17 63.8 12.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3087 PF11286.8 KEZ45940.1 - 0.091 12.2 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) SelP_N PF04592.14 KEZ45940.1 - 2 7.7 9.8 3.8 6.8 9.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Acyl_transf_3 PF01757.22 KEZ45940.1 - 8 5.4 14.0 0.21 10.6 1.4 2.6 3 0 0 3 3 3 0 Acyltransferase family FAD-oxidase_C PF02913.19 KEZ45941.1 - 5e-60 203.2 0.3 9.8e-60 202.3 0.1 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KEZ45941.1 - 1.5e-36 125.2 0.0 3.2e-36 124.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pkinase PF00069.25 KEZ45942.1 - 1.6e-74 250.6 0.0 2.6e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ45942.1 - 5.9e-38 130.6 0.0 1.2e-37 129.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ45942.1 - 0.00029 20.3 0.2 0.88 8.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KEZ45942.1 - 0.00059 19.2 0.5 0.0023 17.3 0.5 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KEZ45942.1 - 0.0065 15.3 0.8 0.018 13.9 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KEZ45942.1 - 0.021 14.7 0.4 0.13 12.1 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-C2H2_4 PF13894.6 KEZ45943.1 - 2.9e-08 33.9 1.8 0.0018 18.9 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ45943.1 - 2.5e-07 30.8 2.1 0.0022 18.3 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KEZ45943.1 - 0.034 14.4 1.4 4.8 7.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Axin_b-cat_bind PF08833.10 KEZ45943.1 - 0.048 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Axin beta-catenin binding domain Ima1_N PF09779.9 KEZ45943.1 - 0.053 14.4 0.5 0.11 13.3 0.2 1.8 2 0 0 2 2 2 0 Ima1 N-terminal domain zf-C2H2_11 PF16622.5 KEZ45943.1 - 0.054 13.3 0.3 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KEZ45943.1 - 0.062 13.3 1.6 0.67 10.0 0.5 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger LicD PF04991.13 KEZ45943.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 LicD family zf-Di19 PF05605.12 KEZ45943.1 - 0.68 10.3 2.4 9.7 6.6 1.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_60s PF00428.19 KEZ45943.1 - 1.5 9.5 11.4 8 7.1 1.6 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_115 PF15979.5 KEZ45944.1 - 1e-135 452.6 0.2 1e-135 452.6 0.2 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KEZ45944.1 - 7.3e-45 152.9 0.0 1.5e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain LepA_C PF06421.12 KEZ45944.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus tRNA-synt_1 PF00133.22 KEZ45945.1 - 5e-148 494.0 0.0 7.2e-148 493.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KEZ45945.1 - 5e-19 68.3 0.0 3.7e-11 42.4 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEZ45945.1 - 2.6e-15 56.7 0.0 5.1e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KEZ45945.1 - 0.0037 16.6 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DUF5066 PF16728.5 KEZ45945.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) HET PF06985.11 KEZ45947.1 - 1.6e-26 93.4 0.2 2.5e-26 92.8 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fasciclin PF02469.22 KEZ45948.1 - 6.6e-21 74.9 0.1 4.1e-18 65.8 0.0 3.1 3 0 0 3 3 3 2 Fasciclin domain Tom37 PF10568.9 KEZ45949.1 - 2.3e-33 115.2 0.4 4.8e-33 114.1 0.4 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KEZ45949.1 - 1.3e-05 25.8 0.0 3.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KEZ45949.1 - 0.016 15.0 0.1 0.037 13.8 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Prolactin_RP PF15172.6 KEZ45949.1 - 0.52 10.0 2.3 0.38 10.4 0.1 1.8 2 0 0 2 2 2 0 Prolactin-releasing peptide UPF0183 PF03676.14 KEZ45950.1 - 4.9e-55 187.4 0.0 7.9e-34 117.6 0.0 3.1 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) tRNA-synt_1 PF00133.22 KEZ45951.1 - 8.1e-232 770.8 0.7 8.8e-231 767.3 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KEZ45951.1 - 4.6e-33 114.3 0.0 1.1e-32 113.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KEZ45951.1 - 4.5e-13 48.7 0.1 0.0011 17.8 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KEZ45951.1 - 2.3e-11 43.6 0.0 8.2e-08 32.0 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KEZ45951.1 - 0.0043 16.4 0.0 0.055 12.8 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Jag_N PF14804.6 KEZ45951.1 - 0.15 12.5 2.3 3.6 8.0 0.3 3.6 3 0 0 3 3 3 0 Jag N-terminus Kinesin PF00225.23 KEZ45952.1 - 3.5e-107 358.2 0.2 7.3e-107 357.1 0.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ45952.1 - 1.8e-23 83.2 0.0 9.6e-23 80.8 0.0 2.4 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KEZ45952.1 - 1.2e-07 32.2 4.3 1.2e-07 32.2 4.3 5.1 5 1 0 5 5 5 1 Kinesin-associated microtubule-binding DUF4208 PF13907.6 KEZ45952.1 - 0.12 12.8 5.2 10 6.6 0.7 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4208) PIN_12 PF16289.5 KEZ45952.1 - 1.1 9.7 6.2 9.2 6.7 0.4 3.3 2 0 0 2 2 2 0 PIN domain RRN9 PF10680.9 KEZ45953.1 - 1.4e-18 66.9 0.1 6.6e-18 64.8 0.1 2.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_aberr PF17017.5 KEZ45953.1 - 0.012 15.8 0.1 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2 PF00096.26 KEZ45953.1 - 0.025 15.0 0.5 0.1 13.1 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KEZ45953.1 - 0.49 10.2 2.5 0.4 10.5 0.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PIG-U PF06728.13 KEZ45954.1 - 5.5e-118 394.3 28.1 6.3e-118 394.1 28.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U HMG-CoA_red PF00368.18 KEZ45955.1 - 2e-139 464.7 5.7 2.5e-139 464.3 5.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KEZ45955.1 - 2.2e-49 167.3 0.3 3.9e-49 166.5 0.3 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KEZ45955.1 - 6.6e-12 45.5 6.5 6e-11 42.4 6.5 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KEZ45955.1 - 6.3e-06 24.6 2.2 9.8e-06 23.9 2.2 1.2 1 0 0 1 1 1 1 Patched family Isochorismatase PF00857.20 KEZ45956.1 - 5.6e-25 88.5 0.0 3.5e-24 85.9 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family DUF3880 PF12996.7 KEZ45956.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 DUF based on E. rectale Gene description (DUF3880) Dabb PF07876.12 KEZ45957.1 - 5.3e-25 87.9 0.0 6.5e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MCRA PF06100.11 KEZ45958.1 - 2.2e-156 521.6 0.0 1.2e-133 446.6 0.0 2.0 2 0 0 2 2 2 2 MCRA family NAD_binding_8 PF13450.6 KEZ45958.1 - 7.2e-05 22.9 0.0 0.00021 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEZ45958.1 - 0.0061 16.6 0.1 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KEZ45958.1 - 0.021 14.4 0.1 0.17 11.4 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trypan_PARP PF05887.11 KEZ45958.1 - 1.9 8.4 16.3 0.074 13.0 9.9 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) GWT1 PF06423.12 KEZ45959.1 - 3.1e-45 153.9 4.5 7e-45 152.8 2.6 2.3 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KEZ45959.1 - 0.0085 16.6 0.0 0.0085 16.6 0.0 3.5 5 1 0 5 5 5 1 Domain of unknown function (DUF4818) Glyco_tranf_2_3 PF13641.6 KEZ45961.1 - 3.3e-19 69.7 0.0 5.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ45961.1 - 4.5e-07 29.5 0.0 9.7e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KEZ45961.1 - 8.6e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF2897 PF11446.8 KEZ45963.1 - 0.1 12.5 0.1 0.33 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Pex14_N PF04695.13 KEZ45963.1 - 2.8 8.6 5.9 2.6 8.7 3.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Claudin_3 PF06653.11 KEZ45963.1 - 9.6 6.1 16.5 3 7.7 6.8 2.9 1 1 0 2 2 2 0 Tight junction protein, Claudin-like CLTH PF10607.9 KEZ45964.1 - 4.4e-34 117.5 0.2 9.4e-34 116.4 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KEZ45964.1 - 1.3e-08 34.7 1.5 2.7e-08 33.7 1.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEZ45964.1 - 1.5e-05 24.9 1.7 3e-05 23.9 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KEZ45964.1 - 3.6e-05 23.5 4.1 6.9e-05 22.6 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ45964.1 - 4.4e-05 23.3 3.7 8.6e-05 22.3 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ45964.1 - 4.9e-05 23.1 1.4 9.3e-05 22.2 1.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KEZ45964.1 - 6.4e-05 23.2 2.1 0.00012 22.4 2.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KEZ45964.1 - 7.7e-05 22.5 2.2 0.00014 21.6 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KEZ45964.1 - 0.00034 20.1 0.2 0.00065 19.1 0.2 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 KEZ45964.1 - 0.0013 18.8 1.5 0.0028 17.8 1.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING AA_synth PF06684.11 KEZ45964.1 - 0.0016 18.0 0.0 0.69 9.4 0.0 2.2 2 0 0 2 2 2 2 Amino acid synthesis zf-RING_4 PF14570.6 KEZ45964.1 - 0.029 14.2 0.9 0.06 13.2 0.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KEZ45964.1 - 0.045 13.7 1.0 0.1 12.6 0.1 2.1 2 0 0 2 2 1 0 Transposase zinc-ribbon domain zf-C2HC5 PF06221.13 KEZ45964.1 - 0.11 12.6 0.2 0.22 11.5 0.2 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-RING_10 PF16685.5 KEZ45964.1 - 0.11 12.7 1.2 0.2 11.8 1.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Translin PF01997.16 KEZ45964.1 - 0.39 10.7 1.6 8.7 6.3 0.1 2.2 2 0 0 2 2 2 0 Translin family zf-Nse PF11789.8 KEZ45964.1 - 2.1 8.2 6.4 7.5 6.5 4.5 2.6 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Tim10_DDP PF02953.15 KEZ45965.1 - 2.5e-15 55.9 1.8 3.3e-15 55.5 1.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger NUDIX PF00293.28 KEZ45966.1 - 6.3e-10 39.2 1.3 8.3e-10 38.8 1.3 1.1 1 0 0 1 1 1 1 NUDIX domain HRI1 PF16815.5 KEZ45967.1 - 0.14 11.8 3.1 0.25 11.0 2.9 1.5 1 1 0 1 1 1 0 Protein HRI1 WRNPLPNID PF15017.6 KEZ45967.1 - 6.5 7.7 20.2 0.13 13.1 3.7 3.7 4 0 0 4 4 4 0 Putative WW-binding domain and destruction box Pro_isomerase PF00160.21 KEZ45969.1 - 9.7e-44 149.4 0.4 1.1e-43 149.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 KEZ45970.1 - 2.4e-46 156.9 0.4 3.6e-46 156.3 0.4 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KEZ45970.1 - 0.00026 20.1 0.1 0.00037 19.6 0.1 1.2 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 KEZ45970.1 - 0.96 9.4 7.2 0.74 9.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Ctr PF04145.15 KEZ45971.1 - 1.7e-39 135.8 0.6 2.1e-39 135.5 0.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.10 KEZ45971.1 - 0.14 10.4 5.5 0.2 9.9 5.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Hemerythrin PF01814.23 KEZ45972.1 - 9.6e-05 23.0 0.4 0.00013 22.6 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Chlorophyllase2 PF12740.7 KEZ45973.1 - 0.0066 15.4 0.0 0.022 13.7 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KEZ45973.1 - 0.052 12.6 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase AXE1 PF05448.12 KEZ45973.1 - 0.19 10.4 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Zip PF02535.22 KEZ45974.1 - 8.5e-52 176.4 0.0 1.4e-51 175.7 0.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Myb_DNA-bind_7 PF15963.5 KEZ45975.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Myb DNA-binding like JAB PF01398.21 KEZ45976.1 - 1.4e-32 112.2 0.0 2.4e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KEZ45976.1 - 1.1e-11 45.1 0.3 2e-11 44.3 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KEZ45976.1 - 1.2e-07 31.6 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.19 KEZ45977.1 - 1.5e-75 254.6 0.4 9e-75 252.0 0.2 2.2 2 1 0 2 2 2 1 Histone deacetylase domain AAA_16 PF13191.6 KEZ45978.1 - 8.8e-08 32.7 2.1 3.4e-07 30.8 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 KEZ45978.1 - 1.6e-06 28.2 0.0 3.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KEZ45978.1 - 0.00021 20.6 0.0 0.00049 19.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain EST1 PF10374.9 KEZ45978.1 - 0.0036 17.9 0.3 0.033 14.8 0.0 2.5 2 0 0 2 2 2 1 Telomerase activating protein Est1 MeaB PF03308.16 KEZ45978.1 - 0.013 14.5 0.0 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 KEZ45978.1 - 0.017 15.5 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 KEZ45978.1 - 0.041 14.1 0.7 0.21 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain zf-C2H2_4 PF13894.6 KEZ45978.1 - 0.32 12.0 4.8 0.39 11.7 0.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DAP3 PF10236.9 KEZ45978.1 - 0.6 9.2 2.0 0.58 9.3 0.0 1.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SNF2_N PF00176.23 KEZ45979.1 - 1.5e-28 99.5 0.3 1.6e-14 53.4 0.2 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ45979.1 - 1.3e-06 28.7 0.0 3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KEZ45979.1 - 0.048 12.9 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase C166 PF17615.2 KEZ45980.1 - 4.4e-27 95.2 3.8 6.1e-27 94.7 3.8 1.1 1 0 0 1 1 1 1 Family of unknown function PPP4R2 PF09184.11 KEZ45981.1 - 6e-09 35.9 6.5 4.1e-08 33.2 5.8 2.3 1 1 0 1 1 1 1 PPP4R2 PsiA PF06952.11 KEZ45981.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 PsiA protein SOG2 PF10428.9 KEZ45981.1 - 0.13 11.5 2.9 0.2 10.8 2.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein AAA_23 PF13476.6 KEZ45982.1 - 2.6e-36 126.0 0.7 2.6e-36 126.0 0.7 7.8 1 1 4 5 5 1 1 AAA domain AAA_21 PF13304.6 KEZ45982.1 - 3.8e-09 36.8 13.7 1.7e-05 24.8 1.4 4.0 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ45982.1 - 3.3e-08 33.2 0.1 3.3e-08 33.2 0.1 2.6 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KEZ45982.1 - 4e-06 27.0 0.0 1.4e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 KEZ45982.1 - 0.00052 19.8 2.4 0.00052 19.8 2.4 5.8 1 1 3 4 4 2 2 AAA ATPase domain AAA_29 PF13555.6 KEZ45982.1 - 0.00062 19.5 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 KEZ45982.1 - 0.04 12.6 0.1 0.04 12.6 0.1 6.8 2 1 5 7 7 5 0 AAA domain AAA_16 PF13191.6 KEZ45982.1 - 0.079 13.3 0.0 0.079 13.3 0.0 5.5 3 2 0 3 3 1 0 AAA ATPase domain ABC_tran PF00005.27 KEZ45982.1 - 0.083 13.4 0.0 0.083 13.4 0.0 6.6 4 2 0 5 5 3 0 ABC transporter RBM39linker PF15519.6 KEZ45982.1 - 0.19 12.8 3.4 26 6.0 0.3 3.5 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Strep_SA_rep PF06696.11 KEZ45982.1 - 3.2 7.9 15.3 27 4.9 1.1 5.7 5 0 0 5 5 5 0 Streptococcal surface antigen repeat PAP_central PF04928.17 KEZ45982.1 - 8.8 5.2 15.6 9.3 5.1 1.8 4.5 4 0 0 4 4 4 0 Poly(A) polymerase central domain PAS_3 PF08447.12 KEZ45983.1 - 2.3e-17 63.1 0.0 4.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold GATA PF00320.27 KEZ45983.1 - 6.9e-16 57.6 6.7 1.3e-15 56.7 6.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 KEZ45983.1 - 2.8e-06 27.6 0.0 6.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 KEZ45983.1 - 4.9e-06 26.6 0.0 9.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KEZ45983.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KEZ45983.1 - 0.0031 17.7 0.1 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 PAS domain DMAP_binding PF06464.11 KEZ45983.1 - 0.015 16.1 3.9 0.056 14.3 1.7 2.3 2 0 0 2 2 2 0 DMAP1-binding Domain Zn-ribbon_8 PF09723.10 KEZ45983.1 - 0.016 15.3 0.1 0.036 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain APG6_N PF17675.1 KEZ45983.1 - 0.044 14.3 4.9 0.082 13.4 4.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region tRNA-synt_1c PF00749.21 KEZ45984.1 - 6.5e-35 120.5 0.2 2.4e-27 95.7 0.1 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KEZ45984.1 - 1.8e-19 70.3 0.0 7.3e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Amidase PF01425.21 KEZ45986.1 - 9.5e-56 189.6 0.2 1.3e-55 189.2 0.2 1.2 1 0 0 1 1 1 1 Amidase Ank PF00023.30 KEZ45987.1 - 6.2e-14 51.7 0.0 2.9e-05 24.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KEZ45987.1 - 2e-13 50.7 0.0 2.4e-09 37.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ45987.1 - 1.3e-12 48.0 0.0 0.0083 16.7 0.0 5.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ45987.1 - 2.3e-11 42.9 0.0 0.0039 17.6 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KEZ45987.1 - 8.5e-09 35.5 0.0 0.00013 22.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) vWA-TerF-like PF10138.9 KEZ45987.1 - 0.00026 21.2 0.0 0.00049 20.3 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus TPR_MLP1_2 PF07926.12 KEZ45990.1 - 8.5e-07 29.1 120.0 0.00091 19.3 5.3 9.7 1 1 5 8 8 8 5 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 KEZ45990.1 - 0.0003 20.7 14.8 0.0003 20.7 14.8 5.3 1 1 4 5 5 3 1 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 KEZ45990.1 - 0.00065 18.7 111.5 0.11 11.4 14.5 6.6 1 1 6 7 7 7 5 Spc7 kinetochore protein HMMR_N PF15905.5 KEZ45990.1 - 0.0014 18.1 27.1 0.0014 18.1 27.1 6.0 1 1 6 7 7 6 2 Hyaluronan mediated motility receptor N-terminal ADIP PF11559.8 KEZ45990.1 - 0.0021 18.2 23.1 0.0064 16.6 7.5 9.7 1 1 8 10 10 10 5 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 KEZ45990.1 - 0.0087 13.6 110.4 0.078 10.5 16.1 3.6 1 1 3 4 4 4 3 Protein of unknown function (DUF3584) DDE_Tnp_1 PF01609.21 KEZ45990.1 - 0.016 14.9 2.1 0.022 14.4 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain PI_PP_I PF18363.1 KEZ45990.1 - 0.24 11.6 2.8 1.1 9.5 0.0 3.4 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain DUF812 PF05667.11 KEZ45990.1 - 6 5.6 100.1 0.39 9.5 20.9 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KEZ45990.1 - 6.4 7.2 108.3 0.4 11.1 22.9 6.3 1 1 5 6 6 6 0 Fez1 DASH_Dad4 PF08650.10 KEZ45990.1 - 7.3 6.6 12.1 0.38 10.7 0.7 4.5 5 0 0 5 5 5 0 DASH complex subunit Dad4 YabA PF06156.13 KEZ45990.1 - 9.2 7.0 73.3 3.8 8.2 4.9 9.3 2 1 4 8 8 8 0 Initiation control protein YabA HeLo PF14479.6 KEZ45991.1 - 7.4e-28 97.8 0.0 1.6e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Vps8 PF12816.7 KEZ45992.1 - 2e-71 239.6 0.0 3.5e-71 238.8 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KEZ45992.1 - 0.00063 19.6 0.2 1.5 8.7 0.0 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 KEZ45992.1 - 0.003 17.5 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KEZ45992.1 - 0.061 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KEZ45992.1 - 0.17 11.6 2.5 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 KEZ45992.1 - 0.18 12.2 0.1 0.46 10.9 0.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 KEZ45992.1 - 4.9 7.3 6.1 0.35 11.0 0.1 2.2 3 0 0 3 3 3 0 Zinc-finger zf-RING_2 PF13639.6 KEZ45993.1 - 1.2e-11 44.8 6.7 1.8e-11 44.2 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KEZ45993.1 - 6.5e-08 32.3 6.4 1e-07 31.7 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ45993.1 - 8e-08 32.0 3.8 1.3e-07 31.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KEZ45993.1 - 8.3e-08 31.8 0.9 1.4e-07 31.1 0.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KEZ45993.1 - 1.4e-06 28.5 8.3 5.4e-06 26.6 8.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KEZ45993.1 - 1.1e-05 25.3 3.7 1.7e-05 24.7 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEZ45993.1 - 0.0025 17.6 2.7 0.0039 17.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KEZ45993.1 - 0.0031 17.6 3.4 0.0065 16.5 3.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KEZ45993.1 - 0.0032 17.4 0.9 0.0032 17.4 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KEZ45993.1 - 0.026 14.3 6.5 0.047 13.5 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KEZ45993.1 - 0.18 11.7 4.5 0.44 10.4 4.6 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KEZ45993.1 - 0.25 11.2 6.0 0.47 10.4 6.0 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KEZ45993.1 - 0.4 10.9 2.9 1 9.6 2.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KEZ45993.1 - 0.76 9.5 5.2 1.5 8.5 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type OAD_gamma PF04277.13 KEZ45993.1 - 0.99 10.0 0.0 0.99 10.0 0.0 3.8 4 1 0 4 4 2 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 KEZ45993.1 - 1 9.5 4.6 2.2 8.5 4.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cwf_Cwc_15 PF04889.12 KEZ45993.1 - 4.9 6.8 13.4 8.9 6.0 13.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pro_isomerase PF00160.21 KEZ45994.1 - 1.7e-51 174.6 0.3 1.9e-51 174.5 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TEA PF01285.18 KEZ45995.1 - 3.3e-24 84.7 0.0 7e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain RRM_1 PF00076.22 KEZ45996.1 - 7.6e-74 243.5 0.5 1.5e-17 63.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KEZ45996.1 - 2e-07 31.0 0.0 0.36 11.0 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif RRM_occluded PF16842.5 KEZ45996.1 - 2.3e-07 30.6 0.0 0.069 13.0 0.0 4.6 5 0 0 5 5 5 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KEZ45996.1 - 1.3e-06 28.3 0.0 9.3 6.3 0.0 4.5 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KEZ45996.1 - 0.0001 21.9 0.0 0.32 10.6 0.0 3.8 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KEZ45996.1 - 0.0002 21.3 0.0 2.2 8.4 0.0 4.7 4 0 0 4 4 4 1 Limkain b1 RRM_3 PF08777.11 KEZ45996.1 - 0.00079 19.4 0.2 0.36 10.9 0.0 4.1 4 1 1 5 5 5 1 RNA binding motif RRM_Rrp7 PF17799.1 KEZ45996.1 - 0.017 14.9 0.0 15 5.3 0.0 4.0 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain T2SSS_2 PF16549.5 KEZ45996.1 - 0.28 11.2 0.9 48 4.0 0.0 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS) pilotin, S protein Dynein_light PF01221.18 KEZ45997.1 - 1.1e-30 105.8 4.8 2.5e-30 104.6 4.8 1.6 1 1 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 KEZ45997.1 - 0.024 14.4 0.1 0.051 13.4 0.0 1.4 1 1 0 1 1 1 0 Immunity protein 48 Methyltransf_16 PF10294.9 KEZ45999.1 - 1.4e-18 67.3 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KEZ45999.1 - 0.029 14.2 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KEZ45999.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF3654 PF12376.8 KEZ46000.1 - 0.11 12.7 0.3 0.26 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) RNA_pol_N PF01194.17 KEZ46001.1 - 8.7e-31 106.0 0.7 1e-30 105.8 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 KEZ46002.1 - 3e-08 34.2 10.9 0.0039 18.0 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ46002.1 - 9.8e-05 22.6 0.7 1.4 9.3 0.0 4.8 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KEZ46002.1 - 0.021 15.3 0.1 0.53 10.9 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.21 KEZ46002.1 - 0.063 13.2 0.3 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat PD40 PF07676.12 KEZ46002.1 - 0.17 11.9 1.2 11 6.2 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DIOX_N PF14226.6 KEZ46003.1 - 4e-33 114.7 0.0 7.2e-32 110.6 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KEZ46003.1 - 1.5e-13 51.1 0.0 2.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 KEZ46003.1 - 0.07 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain zf-met2 PF12907.7 KEZ46004.1 - 1.3e-13 50.8 3.9 2.2e-13 50.1 3.9 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KEZ46004.1 - 1.5e-06 28.9 7.3 2.7e-06 28.2 7.3 1.4 1 0 0 1 1 1 1 4F5 protein family zf-C2H2_12 PF18658.1 KEZ46004.1 - 0.052 13.1 0.7 0.073 12.7 0.7 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type HHH PF00633.23 KEZ46005.1 - 0.00067 19.4 0.3 0.0023 17.7 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KEZ46005.1 - 0.0048 17.5 0.1 0.019 15.6 0.1 2.0 1 1 0 1 1 1 1 Helix-hairpin-helix domain Arc_C PF18162.1 KEZ46005.1 - 0.06 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Arc C-lobe Bap31 PF05529.12 KEZ46006.1 - 9.5e-49 164.7 9.2 1.2e-48 164.4 9.2 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KEZ46006.1 - 7.4e-14 51.5 7.3 1.3e-13 50.7 7.3 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HemX PF04375.14 KEZ46006.1 - 0.0045 16.3 0.4 0.0056 16.0 0.4 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Phage_GP20 PF06810.11 KEZ46006.1 - 0.016 15.0 4.0 0.021 14.7 3.0 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 She9_MDM33 PF05546.11 KEZ46006.1 - 0.039 13.8 0.2 0.072 12.9 0.2 1.4 1 0 0 1 1 1 0 She9 / Mdm33 family HIP1_clath_bdg PF16515.5 KEZ46006.1 - 0.054 14.1 1.9 0.098 13.3 1.9 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin_2 PF01920.20 KEZ46006.1 - 0.069 13.1 3.6 0.11 12.5 3.0 1.6 1 1 0 1 1 1 0 Prefoldin subunit DUF4446 PF14584.6 KEZ46006.1 - 0.069 13.1 0.8 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FlaC_arch PF05377.11 KEZ46006.1 - 0.078 13.4 0.8 0.17 12.3 0.3 1.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 KEZ46006.1 - 0.27 11.5 6.3 0.31 11.3 0.4 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 KEZ46006.1 - 0.38 10.5 6.8 0.2 11.5 2.1 2.7 2 1 1 3 3 3 0 Septum formation initiator Spc24 PF08286.11 KEZ46006.1 - 0.41 10.9 2.7 0.82 9.9 2.4 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 KEZ46006.1 - 0.51 10.7 4.2 1.6 9.1 4.2 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 APG6_N PF17675.1 KEZ46006.1 - 0.64 10.5 7.4 0.12 12.9 3.7 1.6 2 1 0 2 2 1 0 Apg6 coiled-coil region EZH2_N PF18601.1 KEZ46007.1 - 1.5e-27 95.8 0.3 4e-27 94.3 0.3 1.7 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 KEZ46007.1 - 1.2e-21 76.1 0.7 3.2e-21 74.7 0.7 1.7 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 KEZ46007.1 - 7.9e-17 62.1 0.1 5.4e-16 59.4 0.1 2.5 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 KEZ46007.1 - 2.3e-05 24.8 12.8 2.3e-05 24.8 12.8 3.3 1 1 1 2 2 2 1 CXC domain Pil1 PF13805.6 KEZ46008.1 - 2.6e-124 414.0 0.2 3.4e-124 413.6 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 K-box PF01486.17 KEZ46008.1 - 0.0056 16.8 0.9 0.46 10.7 0.1 2.8 2 1 0 2 2 2 2 K-box region zf-C2H2_jaz PF12171.8 KEZ46009.1 - 0.0061 16.8 0.3 0.013 15.8 0.1 1.7 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KEZ46009.1 - 0.039 14.8 5.3 0.2 12.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger UPF0167 PF03691.14 KEZ46009.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-met PF12874.7 KEZ46009.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Peroxin-13_N PF04088.13 KEZ46010.1 - 1.1e-50 171.6 0.0 1.6e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KEZ46010.1 - 9.3e-07 28.4 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KEZ46010.1 - 6.2e-06 25.7 0.0 1.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ46010.1 - 1.9e-05 24.4 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ADH_N PF08240.12 KEZ46011.1 - 1.4e-28 98.9 1.0 2.7e-28 98.0 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ46011.1 - 1.6e-17 63.7 0.0 2.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KEZ46011.1 - 2.8e-05 23.7 1.2 0.0077 15.7 0.6 2.8 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 KEZ46012.1 - 1.9e-31 108.8 0.5 1.5e-30 106.0 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF1748 PF08520.10 KEZ46012.1 - 0.02 14.7 0.1 0.052 13.4 0.1 1.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) SipA_VBS PF17985.1 KEZ46012.1 - 0.59 10.1 3.0 3.8 7.6 0.0 2.9 2 1 0 2 2 2 0 SipA vinculin binding site Methyltransf_23 PF13489.6 KEZ46013.1 - 1.7e-15 57.2 0.0 2.4e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46013.1 - 4.5e-05 24.1 0.0 0.0043 17.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46013.1 - 0.00059 20.5 0.0 0.0049 17.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46013.1 - 0.0014 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ46013.1 - 0.0029 17.1 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KEZ46013.1 - 0.0042 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEZ46013.1 - 0.017 15.3 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 KEZ46013.1 - 0.072 13.8 0.0 0.55 10.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KEZ46013.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TFIIA PF03153.13 KEZ46014.1 - 2.9e-78 264.7 17.3 1.6e-76 259.0 17.3 2.7 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 KEZ46014.1 - 0.13 12.0 2.7 0.18 11.5 2.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 KEZ46015.1 - 1.3e-17 63.8 14.4 0.00032 21.4 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ46015.1 - 2.4e-17 63.0 4.3 4e-05 23.8 0.2 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ46015.1 - 3.2e-06 26.3 0.0 0.00032 19.8 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEZ46015.1 - 7.9e-06 25.9 0.2 0.0005 20.0 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.6 KEZ46016.1 - 6.6e-30 102.9 5.5 8.1e-08 32.2 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KEZ46016.1 - 2.5e-26 91.1 0.5 1.4e-07 31.3 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KEZ46016.1 - 9.7e-25 86.0 3.6 1.7e-05 25.0 0.1 5.8 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 KEZ46016.1 - 1.7e-20 72.2 0.6 7.9e-06 25.6 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KEZ46016.1 - 2.7e-20 71.7 0.1 3.5e-06 26.5 0.1 4.8 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KEZ46016.1 - 5.5e-20 71.2 1.7 6.9e-08 32.6 0.2 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 KEZ46016.1 - 4.5e-08 33.3 0.0 7.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_aberr PF17017.5 KEZ46017.1 - 7.5e-05 22.9 2.0 0.046 13.9 0.1 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KEZ46017.1 - 0.00012 22.3 14.1 0.092 13.2 0.5 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ46017.1 - 0.00032 21.3 14.2 0.084 13.8 1.2 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ46017.1 - 0.0044 17.3 6.2 0.12 12.7 0.7 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KEZ46017.1 - 0.044 14.2 0.8 0.044 14.2 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 KEZ46017.1 - 0.47 10.9 11.6 0.15 12.5 1.7 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HIG_1_N PF04588.13 KEZ46018.1 - 5.6e-05 23.3 1.5 5.6e-05 23.3 1.5 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Dus PF01207.17 KEZ46019.1 - 3.1e-39 134.9 0.0 3e-27 95.5 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) SPX PF03105.19 KEZ46019.1 - 0.0021 18.1 1.7 0.0033 17.4 1.7 1.3 1 0 0 1 1 1 1 SPX domain zf_CCCH_4 PF18345.1 KEZ46019.1 - 0.17 12.0 6.3 0.96 9.6 1.0 2.5 2 0 0 2 2 2 0 Zinc finger domain Metallophos PF00149.28 KEZ46020.1 - 5.2e-35 121.8 0.0 8.3e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KEZ46020.1 - 1.4e-17 63.9 0.2 5.1e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Ank_5 PF13857.6 KEZ46021.1 - 5.6e-10 39.3 0.5 0.00065 19.9 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ46021.1 - 3.8e-09 37.0 0.0 9.3e-07 29.4 0.0 3.9 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) NACHT PF05729.12 KEZ46021.1 - 3.3e-08 33.6 0.1 7.3e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KEZ46021.1 - 1.8e-07 31.7 0.0 4.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Ank_4 PF13637.6 KEZ46021.1 - 6.9e-06 26.5 0.0 0.002 18.6 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 KEZ46021.1 - 7e-06 26.4 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Ank_3 PF13606.6 KEZ46021.1 - 0.00085 19.6 0.1 44 5.1 0.0 5.0 4 0 0 4 4 4 0 Ankyrin repeat KAP_NTPase PF07693.14 KEZ46021.1 - 0.0047 16.2 0.0 0.022 14.0 0.0 1.8 1 1 1 2 2 2 1 KAP family P-loop domain TrwB_AAD_bind PF10412.9 KEZ46021.1 - 0.15 10.9 0.0 0.48 9.3 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RRF PF01765.19 KEZ46022.1 - 1.3e-26 93.4 0.4 2.7e-26 92.5 0.4 1.5 1 0 0 1 1 1 1 Ribosome recycling factor WD40 PF00400.32 KEZ46022.1 - 3.8e-15 56.0 14.3 4e-05 24.3 0.2 8.9 10 0 0 10 10 10 4 WD domain, G-beta repeat Nup160 PF11715.8 KEZ46022.1 - 0.016 13.9 0.0 14 4.2 0.0 3.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 SCAN PF02023.17 KEZ46022.1 - 0.083 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 SCAN domain Nup214_FG PF18617.1 KEZ46022.1 - 0.14 12.7 3.2 0.1 13.1 0.4 2.2 2 0 0 2 2 2 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Aldedh PF00171.22 KEZ46023.1 - 3.2e-163 543.6 0.5 3.7e-163 543.3 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HATPase_c PF02518.26 KEZ46024.1 - 3.9e-25 88.5 0.7 1.2e-24 86.9 0.3 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KEZ46024.1 - 1.7e-20 73.3 0.0 4.4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 KEZ46024.1 - 1.5e-09 38.1 0.0 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 KEZ46024.1 - 8.9e-08 32.3 0.0 0.00011 22.5 0.0 2.8 2 0 0 2 2 2 2 PAS domain HisKA PF00512.25 KEZ46024.1 - 2.5e-06 27.4 0.0 9.1e-06 25.6 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 KEZ46024.1 - 3.8e-06 26.9 0.0 8.4e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KEZ46024.1 - 0.0018 18.5 3.3 0.0019 18.5 0.2 2.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 KEZ46024.1 - 0.0086 16.1 0.0 0.09 12.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain PH_6 PF15406.6 KEZ46025.1 - 5e-37 126.6 4.5 5e-37 126.6 4.5 3.9 4 1 1 5 5 5 1 Pleckstrin homology domain PH PF00169.29 KEZ46025.1 - 8.5e-06 26.2 0.0 2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PH domain tRNA-synt_2 PF00152.20 KEZ46026.1 - 3.3e-61 207.1 0.0 1.5e-47 162.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KEZ46026.1 - 3e-09 36.7 0.0 5.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KEZ46026.1 - 0.00031 20.3 0.0 0.068 12.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Actin PF00022.19 KEZ46027.1 - 1.9e-146 487.8 0.0 2.2e-146 487.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KEZ46027.1 - 7.4e-06 25.0 0.0 0.0033 16.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF1651 PF07864.11 KEZ46027.1 - 0.0055 17.0 0.2 0.089 13.2 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1651) SRF-TF PF00319.18 KEZ46028.1 - 1.5e-22 78.8 0.1 2.6e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Fungal_trans PF04082.18 KEZ46029.1 - 9.3e-14 51.1 0.0 1.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46029.1 - 3.6e-08 33.4 9.4 5.9e-08 32.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EFhand_Ca_insen PF08726.10 KEZ46029.1 - 0.04 14.0 0.4 0.86 9.7 0.0 2.4 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Fungal_trans PF04082.18 KEZ46030.1 - 7.4e-09 35.0 0.0 1.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gag_p24 PF00607.20 KEZ46030.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) VPS9 PF02204.18 KEZ46031.1 - 5.7e-20 71.5 0.0 1.2e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KEZ46031.1 - 7.5e-17 61.4 0.1 1.5e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KEZ46031.1 - 4.6e-09 35.8 0.1 4.3e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 CUE domain PhoLip_ATPase_C PF16212.5 KEZ46032.1 - 5.3e-65 219.6 19.1 5.3e-65 219.6 19.1 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KEZ46032.1 - 1.3e-21 76.0 2.1 2.2e-20 72.1 0.2 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KEZ46032.1 - 1.4e-11 44.3 0.0 1.4e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ46032.1 - 8.8e-11 42.5 0.1 1.3e-05 25.6 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KEZ46032.1 - 1.2e-07 31.5 0.1 2.8e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KEZ46032.1 - 0.0055 16.5 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 KEZ46033.1 - 2.3e-40 138.6 59.5 3e-40 138.2 52.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Tmemb_18A PF09771.9 KEZ46033.1 - 2 8.9 3.8 2 8.8 0.7 2.3 2 0 0 2 2 2 0 Transmembrane protein 188 AAA PF00004.29 KEZ46034.1 - 1.9e-17 63.9 0.0 3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ46034.1 - 0.00024 21.5 0.1 0.00088 19.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KEZ46034.1 - 0.00025 21.0 0.0 0.00073 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ46034.1 - 0.00039 20.7 0.1 0.0028 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KEZ46034.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KEZ46034.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KEZ46034.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ46034.1 - 0.12 12.1 0.3 0.25 11.1 0.3 1.6 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 KEZ46034.1 - 0.12 12.0 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 KEZ46034.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KEZ46034.1 - 0.14 11.8 0.4 1.8 8.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 KEZ46034.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_2 PF07724.14 KEZ46034.1 - 0.17 12.0 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) SNF5 PF04855.12 KEZ46035.1 - 2.7e-87 292.5 0.0 3.7e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 A_deaminase PF00962.22 KEZ46035.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase TPR_21 PF09976.9 KEZ46036.1 - 8.2e-07 28.9 0.1 1.5e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KEZ46036.1 - 2.1e-05 24.6 0.0 6.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46036.1 - 3.6e-05 23.6 0.1 0.017 15.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 KEZ46036.1 - 4.2e-05 22.6 0.0 6e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_1 PF00515.28 KEZ46036.1 - 5.3e-05 22.9 0.0 0.019 14.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ46036.1 - 7.1e-05 22.6 0.0 0.054 13.6 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46036.1 - 0.0012 19.3 0.1 0.76 10.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ46036.1 - 0.015 16.0 0.3 1 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46036.1 - 0.044 14.6 1.3 3.1 8.9 0.1 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_7 PF00840.20 KEZ46037.1 - 3.6e-205 681.7 21.1 4.4e-205 681.5 21.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KEZ46037.1 - 1e-14 54.2 11.9 1e-14 54.2 11.9 4.6 4 1 0 4 4 4 1 Fungal cellulose binding domain CUE PF02845.16 KEZ46038.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 KEZ46038.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Glyco_hydro_7 PF00840.20 KEZ46039.1 - 6.9e-190 631.4 6.0 7.8e-190 631.2 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Hexapep PF00132.24 KEZ46040.1 - 4.4e-07 29.4 1.4 0.00087 18.9 0.6 3.2 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KEZ46040.1 - 2.8e-05 23.2 0.2 4.5e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KEZ46040.1 - 3.9e-05 24.1 0.0 9.4e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KEZ46040.1 - 0.00031 19.0 0.7 0.00044 18.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 KEZ46040.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.6 KEZ46040.1 - 0.07 12.9 5.5 0.085 12.6 0.9 2.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-C2H2 PF00096.26 KEZ46041.1 - 1.4e-05 25.3 13.5 0.0036 17.7 4.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KEZ46041.1 - 0.024 15.3 0.3 0.024 15.3 0.3 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KEZ46041.1 - 0.1 13.5 10.7 1.9 9.6 3.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger LRR_4 PF12799.7 KEZ46042.1 - 4.1e-05 23.9 0.2 2 8.9 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KEZ46042.1 - 0.0054 16.6 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KEZ46042.1 - 0.056 13.2 0.1 6 6.7 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat Ribosomal_S8e PF01201.22 KEZ46043.1 - 2.5e-55 186.4 0.8 2.9e-55 186.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF913 PF06025.12 KEZ46044.1 - 5.8e-117 390.8 0.0 5.8e-117 390.8 0.0 6.1 6 1 0 6 6 6 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KEZ46044.1 - 1.6e-111 373.2 0.0 1.6e-111 373.2 0.0 3.9 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KEZ46044.1 - 1.9e-97 326.4 0.0 3e-97 325.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KEZ46044.1 - 9.9e-24 82.0 18.1 6.3e-08 31.8 0.2 4.2 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 KEZ46044.1 - 0.014 15.3 1.6 0.052 13.5 0.8 2.4 2 0 0 2 2 2 0 UBA/TS-N domain RabGAP-TBC PF00566.18 KEZ46045.1 - 5.3e-50 170.0 2.3 5.2e-48 163.5 0.0 3.0 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Jnk-SapK_ap_N PF09744.9 KEZ46045.1 - 0.00015 22.0 21.3 0.00015 22.0 21.3 3.9 4 1 1 5 5 5 1 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 KEZ46045.1 - 0.00018 21.6 6.0 0.00018 21.6 6.0 4.0 4 1 1 5 5 5 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 KEZ46045.1 - 0.059 13.6 20.7 0.1 12.8 0.4 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 KEZ46045.1 - 0.47 10.9 9.2 1.7 9.1 2.1 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 KEZ46045.1 - 1.7 8.7 25.4 1.9e+03 -1.2 25.3 3.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HMMR_N PF15905.5 KEZ46045.1 - 4 6.8 34.5 0.24 10.8 23.0 2.9 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal HMMR_C PF15908.5 KEZ46045.1 - 8.9 6.6 21.4 0.9 9.8 2.1 3.9 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor C-terminal DUF1664 PF07889.12 KEZ46045.1 - 9.1 6.3 13.5 2.4 8.2 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fungal_trans PF04082.18 KEZ46046.1 - 2e-12 46.8 0.5 3.2e-12 46.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46046.1 - 3.2e-05 23.9 9.1 5.2e-05 23.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hepatitis_core PF00906.20 KEZ46046.1 - 1.9 8.0 5.9 4.1 6.9 1.7 2.3 2 0 0 2 2 2 0 Hepatitis core antigen bZIP_1 PF00170.21 KEZ46046.1 - 5.5 7.2 11.8 5.8 7.1 0.1 2.9 3 0 0 3 3 3 0 bZIP transcription factor AbiEii PF08843.11 KEZ46047.1 - 4e-06 27.0 0.0 8.4e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system NTP_transf_5 PF14907.6 KEZ46047.1 - 0.013 15.2 0.1 0.024 14.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase CDP-OH_P_tran_2 PF08009.11 KEZ46047.1 - 0.14 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 DOCK_N PF16172.5 KEZ46048.1 - 1.2e-116 389.8 0.8 1.8e-116 389.2 0.0 1.7 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 KEZ46048.1 - 4e-35 121.4 1.9 2.8e-34 118.7 1.9 2.0 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KEZ46048.1 - 1.2e-34 119.9 0.0 2.2e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KEZ46048.1 - 2.4e-05 23.8 0.0 5.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KEZ46048.1 - 0.00083 19.2 0.0 0.0044 16.9 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KEZ46048.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain DUF4360 PF14273.6 KEZ46049.1 - 2.5e-12 47.1 0.0 4.9e-10 39.6 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4360) DUF2407_C PF13373.6 KEZ46051.1 - 1.1e-36 126.0 0.3 2.8e-36 124.8 0.3 1.7 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KEZ46051.1 - 6.7e-22 78.0 0.1 3.4e-21 75.7 0.1 2.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Ras PF00071.22 KEZ46051.1 - 3.5e-08 33.2 0.0 5.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ras family ubiquitin PF00240.23 KEZ46051.1 - 0.093 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family rRNA_proc-arch PF13234.6 KEZ46052.1 - 8.3e-83 278.4 0.0 1.5e-82 277.6 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KEZ46052.1 - 5.5e-50 169.2 3.8 6.3e-50 169.0 2.0 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KEZ46052.1 - 3.9e-17 62.6 0.0 2.1e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ46052.1 - 5e-06 26.8 0.0 2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ46052.1 - 1.7e-05 24.9 0.0 4.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KEZ46052.1 - 0.063 13.5 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KEZ46052.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NDUFB11 PF17250.2 KEZ46053.1 - 0.024 15.3 2.2 0.096 13.3 2.2 2.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Nif11 PF07862.11 KEZ46053.1 - 0.27 11.6 3.2 1.7 9.0 3.2 2.5 1 0 0 1 1 1 0 Nif11 domain Cyt-b5 PF00173.28 KEZ46054.1 - 2.1e-10 40.6 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CENP-X PF09415.10 KEZ46056.1 - 1.2e-21 76.7 0.2 2e-21 76.1 0.2 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 KEZ46056.1 - 0.11 12.7 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 KEZ46057.1 - 4.3e-68 225.3 3.9 9.8e-24 83.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.15 KEZ46058.1 - 1.6e-39 134.2 4.2 1.7e-39 134.1 4.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 KEZ46058.1 - 0.0021 17.9 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 KEZ46058.1 - 0.012 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator RNA_pol_Rpc34 PF05158.12 KEZ46058.1 - 0.015 14.7 0.2 0.032 13.6 0.1 1.5 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 KEZ46058.1 - 0.03 13.9 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EAP30 PF04157.16 KEZ46058.1 - 0.035 13.4 0.1 0.041 13.2 0.1 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_27 PF13463.6 KEZ46058.1 - 0.036 14.6 0.1 0.045 14.3 0.1 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain TrmB PF01978.19 KEZ46058.1 - 0.038 13.9 0.3 0.052 13.4 0.3 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 KEZ46058.1 - 0.058 13.6 0.1 0.089 13.0 0.1 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Ribosomal_S7 PF00177.21 KEZ46059.1 - 7.8e-38 129.5 1.9 9.7e-38 129.1 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NPP1 PF05630.11 KEZ46060.1 - 2e-62 210.8 0.0 2.3e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) BTB_2 PF02214.22 KEZ46061.1 - 2.3e-07 31.0 0.1 0.00027 21.2 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Pyridoxal_deC PF00282.19 KEZ46062.1 - 1.7e-75 254.1 0.0 2.2e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KEZ46062.1 - 5e-07 29.0 0.0 9.9e-07 28.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEZ46062.1 - 0.0072 15.7 0.3 0.027 13.8 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 KEZ46062.1 - 0.067 11.9 0.0 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Abhydrolase_3 PF07859.13 KEZ46063.1 - 7.1e-35 120.8 0.0 4.4e-24 85.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KEZ46063.1 - 0.22 10.3 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase RNA_pol_Rpc4 PF05132.14 KEZ46063.1 - 1.1 9.6 4.9 0.72 10.3 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Aminotran_3 PF00202.21 KEZ46064.1 - 2e-109 365.9 0.0 2.7e-109 365.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KEZ46064.1 - 0.0057 15.9 0.0 0.0092 15.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DUF5070 PF16802.5 KEZ46064.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) Ufd2P_core PF10408.9 KEZ46065.1 - 2.9e-212 706.7 1.1 4.2e-212 706.2 1.1 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KEZ46065.1 - 1.4e-24 86.1 0.8 5e-24 84.3 0.8 2.0 1 0 0 1 1 1 1 U-box domain Peptidase_C2 PF00648.21 KEZ46066.1 - 1.4e-63 214.7 4.3 1.5e-62 211.3 4.3 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease SPO22 PF08631.10 KEZ46067.1 - 4.5e-61 206.8 4.8 2.7e-59 201.0 0.4 3.4 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KEZ46067.1 - 4.6e-06 26.8 1.7 0.0086 16.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2390 PF09523.10 KEZ46067.1 - 1 9.7 5.4 2.2 8.6 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2390) TPR_2 PF07719.17 KEZ46067.1 - 6.6 7.1 12.5 0.84 9.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat PAS PF00989.25 KEZ46068.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Mic1 PF07035.12 KEZ46068.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Ald_Xan_dh_C2 PF02738.18 KEZ46069.1 - 1.1e-206 687.6 0.6 1.5e-206 687.1 0.6 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KEZ46069.1 - 2e-46 157.9 0.0 4.3e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KEZ46069.1 - 1.7e-31 108.9 0.0 4.5e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KEZ46069.1 - 2.6e-29 101.4 0.6 1e-28 99.5 0.1 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KEZ46069.1 - 1.5e-28 98.6 0.0 4.4e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KEZ46069.1 - 1.1e-08 34.9 0.4 4e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 KEZ46069.1 - 0.014 15.5 0.1 0.044 13.8 0.1 1.8 1 0 0 1 1 1 0 DUF218 domain APH PF01636.23 KEZ46070.1 - 1.1e-06 28.8 0.0 1.5e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Aldedh PF00171.22 KEZ46071.1 - 1.4e-134 449.2 0.1 1.6e-134 448.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Stathmin PF00836.19 KEZ46071.1 - 0.017 15.1 0.7 0.032 14.2 0.7 1.4 1 0 0 1 1 1 0 Stathmin family HicB_lk_antitox PF15919.5 KEZ46071.1 - 0.086 13.0 1.8 2.8 8.0 1.7 2.7 2 1 1 3 3 3 0 HicB_like antitoxin of bacterial toxin-antitoxin system GCH_III PF05165.12 KEZ46071.1 - 0.094 12.0 0.4 0.21 10.8 0.4 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase III PmbA_TldD PF01523.16 KEZ46071.1 - 0.16 11.8 0.7 0.31 10.8 0.7 1.4 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DUF5633 PF18656.1 KEZ46071.1 - 1.7 8.6 5.5 0.54 10.2 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Aminotran_1_2 PF00155.21 KEZ46072.1 - 2.5e-68 230.9 0.0 2.8e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEZ46072.1 - 0.002 17.5 0.0 0.0043 16.4 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KEZ46072.1 - 0.0027 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KEZ46072.1 - 0.0037 15.9 0.0 0.0074 14.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEZ46072.1 - 0.0087 15.0 0.0 0.016 14.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Steroid_dh PF02544.16 KEZ46073.1 - 5.1e-20 72.0 2.3 8.5e-19 68.0 2.3 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KEZ46073.1 - 3.3e-05 23.5 1.3 5.6e-05 22.8 0.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) MINDY_DUB PF04424.13 KEZ46074.1 - 2.9e-22 78.9 0.0 4.5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase SprA-related PF12118.8 KEZ46074.1 - 2.4 7.2 5.1 4.1 6.4 5.1 1.3 1 0 0 1 1 1 0 SprA-related family DUF1977 PF09320.11 KEZ46075.1 - 1e-27 96.4 0.3 3.3e-26 91.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KEZ46075.1 - 2.4e-19 69.2 0.2 4.3e-19 68.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 KEZ46076.1 - 7.4e-07 29.5 0.6 2.6e-06 27.7 0.2 1.9 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 DUF4536 PF15055.6 KEZ46076.1 - 0.062 13.6 0.8 0.45 10.8 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) Y_phosphatase2 PF03162.13 KEZ46077.1 - 1.3e-41 142.0 0.0 1.8e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KEZ46077.1 - 1.8e-10 41.2 0.0 2.4e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KEZ46077.1 - 6.4e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KEZ46077.1 - 0.00021 20.9 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ima1_N PF09779.9 KEZ46078.1 - 7.7e-23 81.8 2.3 1.7e-22 80.8 2.3 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain MRP-S25 PF13741.6 KEZ46079.1 - 5.5e-62 209.3 11.5 2.6e-58 197.3 3.7 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KEZ46079.1 - 0.0054 17.0 3.0 0.012 15.9 1.4 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S23 COX7C PF02935.16 KEZ46080.1 - 2.8e-23 81.9 2.4 3.1e-23 81.8 2.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Frataxin_Cyay PF01491.16 KEZ46081.1 - 3.5e-21 75.3 2.9 8.4e-15 54.8 0.0 2.1 1 1 1 2 2 2 2 Frataxin-like domain Beta-lactamase PF00144.24 KEZ46081.1 - 0.077 12.2 0.1 1.9 7.7 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase SeqA_N PF17206.3 KEZ46081.1 - 0.096 12.0 0.3 0.23 10.8 0.3 1.5 1 0 0 1 1 1 0 SeqA protein N-terminal domain AIG1 PF04548.16 KEZ46082.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 KEZ46082.1 - 3.4e-05 23.9 0.0 9.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ46082.1 - 0.0032 17.9 0.1 0.0084 16.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ46082.1 - 0.0043 17.0 0.1 0.012 15.6 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 KEZ46082.1 - 0.0047 16.7 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KEZ46082.1 - 0.016 15.8 0.2 0.038 14.5 0.2 1.7 1 0 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 KEZ46082.1 - 0.037 13.6 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 KEZ46082.1 - 0.057 13.2 0.2 0.16 11.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KEZ46082.1 - 0.071 13.4 0.2 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KEZ46082.1 - 0.11 13.0 0.1 0.29 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KEZ46082.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KEZ46082.1 - 0.18 11.3 0.1 0.29 10.7 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Methyltrans_RNA PF04452.14 KEZ46083.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Clat_adaptor_s PF01217.20 KEZ46084.1 - 2.2e-31 108.7 0.0 4e-31 107.9 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_1 PF00133.22 KEZ46085.1 - 1.6e-40 139.0 0.1 1e-32 113.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KEZ46085.1 - 3.9e-15 55.5 0.1 2.9e-08 32.9 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KEZ46085.1 - 1.6e-12 47.6 0.2 4.7e-12 46.1 0.2 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KEZ46085.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain zf-CSL PF05207.13 KEZ46086.1 - 7.2e-23 80.1 0.8 9.2e-23 79.7 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KEZ46086.1 - 0.00021 21.3 0.7 0.00031 20.8 0.7 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 KEZ46086.1 - 0.0013 17.4 0.2 0.0016 17.1 0.2 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Prok-RING_1 PF14446.6 KEZ46086.1 - 0.35 10.8 2.3 0.69 9.9 2.3 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_membrane_2 PF06472.15 KEZ46087.1 - 1.4e-102 342.7 1.2 2.2e-102 342.1 1.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KEZ46087.1 - 1.4e-18 67.8 0.0 2.8e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KEZ46087.1 - 0.0003 20.7 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KEZ46087.1 - 0.04 14.4 0.2 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ46087.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KEZ46087.1 - 0.088 13.2 1.1 0.47 10.8 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 KEZ46087.1 - 0.095 12.1 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KEZ46087.1 - 0.13 11.6 0.1 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KEZ46087.1 - 0.15 11.8 0.0 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KEZ46087.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain IBR PF01485.21 KEZ46088.1 - 3.6e-18 65.5 36.9 7.4e-11 42.1 4.8 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DNA_ligase_ZBD PF03119.16 KEZ46088.1 - 0.08 13.0 4.5 1.4 9.0 0.0 3.0 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF2752 PF10825.8 KEZ46088.1 - 0.17 12.0 2.9 12 6.0 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-ribbon_3 PF13248.6 KEZ46088.1 - 0.66 9.5 9.1 1.8 8.1 0.2 3.8 3 0 0 3 3 3 0 zinc-ribbon domain YhfH PF14149.6 KEZ46088.1 - 1 9.4 13.3 2.5 8.2 3.3 3.6 3 0 0 3 3 3 0 YhfH-like protein HSP70 PF00012.20 KEZ46089.1 - 0.0019 16.5 2.0 0.034 12.3 0.1 2.9 3 1 0 3 3 3 2 Hsp70 protein JmjC PF02373.22 KEZ46090.1 - 5.5e-38 129.9 0.3 1.5e-37 128.5 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KEZ46090.1 - 1.1e-17 64.1 3.9 1.9e-17 63.4 3.9 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KEZ46090.1 - 2.8e-17 62.8 2.9 6.7e-17 61.5 2.9 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 KEZ46090.1 - 7.4e-14 51.4 1.3 2.3e-13 49.9 1.3 1.9 1 0 0 1 1 1 1 jmjN domain PAP2 PF01569.21 KEZ46091.1 - 1.4e-20 73.4 0.8 4.4e-20 71.8 0.8 1.8 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KEZ46091.1 - 0.00044 20.0 2.6 0.00044 20.0 2.6 2.1 2 0 0 2 2 2 1 PAP2 superfamily CHD5 PF04420.14 KEZ46091.1 - 0.47 10.3 2.5 0.31 10.9 0.2 1.8 2 0 0 2 2 2 0 CHD5-like protein QueT PF06177.11 KEZ46091.1 - 5.7 7.3 9.1 1.3 9.4 5.0 2.2 2 1 0 2 2 2 0 QueT transporter adh_short_C2 PF13561.6 KEZ46092.1 - 8.2e-30 104.1 0.2 1.2e-25 90.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ46092.1 - 8.5e-29 100.4 0.3 5.8e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KEZ46092.1 - 4.5e-07 29.9 2.1 3.2e-06 27.2 2.1 2.0 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KEZ46092.1 - 9.2e-06 25.6 0.4 1.5e-05 25.0 0.4 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KEZ46092.1 - 0.00016 21.4 0.2 0.00024 20.8 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KEZ46092.1 - 0.00086 19.7 0.1 0.0016 18.8 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.21 KEZ46092.1 - 0.0042 16.6 0.4 0.0078 15.7 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KEZ46092.1 - 0.01 15.4 0.4 0.015 14.9 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 KEZ46092.1 - 0.018 15.3 0.4 0.046 14.0 0.4 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ParD_antitoxin PF03693.14 KEZ46092.1 - 0.022 15.2 0.0 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH F420_oxidored PF03807.17 KEZ46092.1 - 0.028 15.0 0.4 0.067 13.8 0.4 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 KEZ46092.1 - 0.034 14.0 0.2 0.059 13.2 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 KEZ46092.1 - 0.035 13.4 0.1 0.29 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.14 KEZ46092.1 - 0.043 13.0 0.1 0.06 12.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KEZ46093.1 - 4.2e-75 252.3 0.0 6.1e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KEZ46093.1 - 3.1e-22 78.9 1.6 1e-21 77.3 1.6 1.9 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KEZ46093.1 - 1.7e-05 24.9 0.6 0.00032 20.7 0.2 2.4 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 KEZ46093.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 KEZ46093.1 - 0.0021 18.5 0.0 0.0075 16.7 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 KEZ46093.1 - 0.1 12.9 0.2 15 5.9 0.1 2.7 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KEZ46093.1 - 0.13 12.9 0.1 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Q_salvage PF10343.9 KEZ46094.1 - 8.5e-127 422.5 0.0 1e-126 422.3 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DNA_pol_delta_4 PF04081.13 KEZ46095.1 - 5.1e-37 127.1 7.4 2e-36 125.3 7.4 1.9 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 WD40 PF00400.32 KEZ46095.1 - 1.1e-19 70.3 14.0 2.8e-07 31.1 0.8 6.5 7 0 0 7 7 6 5 WD domain, G-beta repeat Ribosomal_L32p PF01783.23 KEZ46095.1 - 5e-13 49.1 6.8 5e-13 49.1 6.8 1.8 2 0 0 2 2 1 1 Ribosomal L32p protein family ANAPC4_WD40 PF12894.7 KEZ46095.1 - 2e-10 40.8 1.9 0.021 15.1 0.4 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KEZ46095.1 - 0.0039 16.6 0.0 0.027 13.8 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 KEZ46095.1 - 0.023 13.4 0.1 1.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KEZ46095.1 - 0.026 14.4 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KEZ46095.1 - 0.029 12.9 0.1 0.14 10.7 0.0 1.7 1 1 0 2 2 2 0 Cytochrome D1 heme domain zinc-ribbons_6 PF07191.12 KEZ46095.1 - 0.068 13.2 1.4 0.13 12.3 1.4 1.3 1 0 0 1 1 1 0 zinc-ribbons Ge1_WD40 PF16529.5 KEZ46095.1 - 0.094 11.7 0.3 3.9 6.3 0.0 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 KEZ46095.1 - 0.12 12.1 0.3 0.98 9.1 0.0 2.5 3 0 0 3 3 3 0 TUP1-like enhancer of split Kelch_6 PF13964.6 KEZ46095.1 - 0.14 12.4 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 Kelch motif DUF3306 PF11748.8 KEZ46095.1 - 1.1 10.2 9.1 43 5.0 7.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Pox_Ag35 PF03286.14 KEZ46095.1 - 1.3 8.8 6.8 3.1 7.5 6.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Septin PF00735.18 KEZ46096.1 - 2.8e-113 377.9 0.7 3.3e-113 377.6 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KEZ46096.1 - 4.8e-08 33.1 0.0 9.4e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ46096.1 - 2.2e-05 24.4 0.2 0.00042 20.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KEZ46096.1 - 2.3e-05 24.0 0.5 0.013 15.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KEZ46096.1 - 3.7e-05 23.1 0.0 6.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KEZ46096.1 - 0.003 17.7 0.9 2.3 8.2 0.1 2.6 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.6 KEZ46096.1 - 0.0049 17.2 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KEZ46096.1 - 0.0069 15.9 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 KEZ46096.1 - 0.0077 16.6 0.0 0.031 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KEZ46096.1 - 0.015 15.8 0.3 0.024 15.1 0.3 1.7 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 KEZ46096.1 - 0.018 14.4 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.22 KEZ46096.1 - 0.033 13.4 0.1 0.059 12.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 KEZ46096.1 - 0.048 12.8 0.7 0.21 10.7 0.6 2.0 1 1 0 1 1 1 0 G-protein alpha subunit Microtub_bd PF16796.5 KEZ46096.1 - 0.087 12.8 0.1 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 Microtubule binding Roc PF08477.13 KEZ46096.1 - 0.089 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KEZ46096.1 - 0.14 11.8 0.0 0.47 10.0 0.0 1.9 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.6 KEZ46096.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 KEZ46097.1 - 3e-61 206.3 0.0 3.5e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 KEZ46097.1 - 1.3e-06 28.4 0.0 9.3e-06 25.7 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KEZ46097.1 - 8.9e-05 23.0 0.0 0.00019 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ46097.1 - 0.00015 22.2 0.0 0.00036 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ46097.1 - 0.00037 20.4 0.1 0.00091 19.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KEZ46097.1 - 0.0012 19.1 0.3 0.066 13.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ46097.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KEZ46097.1 - 0.016 15.4 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KEZ46097.1 - 0.031 14.2 0.1 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 KEZ46097.1 - 0.048 13.3 0.0 0.46 10.1 0.0 2.0 1 1 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.6 KEZ46097.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 KEZ46097.1 - 0.098 12.5 0.1 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_29 PF13555.6 KEZ46097.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_72 PF03198.14 KEZ46098.1 - 2.7e-117 391.5 0.0 3.3e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KEZ46098.1 - 0.00051 19.6 0.0 0.012 15.1 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Citrate_bind PF16114.5 KEZ46099.1 - 4.8e-86 286.8 0.0 6.5e-86 286.3 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KEZ46099.1 - 5.5e-09 35.9 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KEZ46099.1 - 0.0023 16.1 0.0 0.0031 15.7 0.0 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 KEZ46100.1 - 2e-20 73.2 0.0 2.8e-17 62.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KEZ46100.1 - 2e-19 70.1 0.1 5.8e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KEZ46100.1 - 2.6e-15 56.5 0.1 5.1e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KEZ46100.1 - 4.9e-06 26.4 0.0 0.00014 21.7 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Arena_RNA_pol PF06317.11 KEZ46100.1 - 0.13 9.4 0.0 0.18 9.0 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase MRG PF05712.13 KEZ46101.1 - 1.2e-57 194.4 0.4 1.7e-57 193.9 0.4 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KEZ46101.1 - 3.3e-08 33.3 0.2 7.1e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KEZ46101.1 - 0.049 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Agenet PF05641.12 KEZ46101.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Agenet domain Methyltransf_23 PF13489.6 KEZ46102.1 - 3.5e-18 66.0 0.0 5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46102.1 - 7.7e-13 49.0 0.0 2.4e-12 47.4 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46102.1 - 7.1e-10 39.5 0.0 8.5e-09 36.1 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46102.1 - 8.2e-10 39.2 0.0 3.2e-09 37.3 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46102.1 - 3.4e-08 33.4 0.0 3.3e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ46102.1 - 0.00017 21.0 0.0 0.0058 16.0 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEZ46102.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KEZ46102.1 - 0.0073 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KEZ46102.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KEZ46102.1 - 0.018 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_15 PF09445.10 KEZ46102.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 KEZ46102.1 - 0.037 13.4 0.0 0.086 12.2 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 KEZ46102.1 - 0.056 13.2 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cnl2_NKP2 PF09447.10 KEZ46103.1 - 9.4e-27 93.0 0.5 1.7e-26 92.1 0.5 1.5 1 0 0 1 1 1 1 Cnl2/NKP2 family protein HAUS-augmin3 PF14932.6 KEZ46103.1 - 0.00073 19.2 0.9 0.001 18.8 0.8 1.3 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 Prefoldin_2 PF01920.20 KEZ46103.1 - 0.0018 18.2 1.6 0.0025 17.8 0.2 1.9 2 1 0 2 2 2 1 Prefoldin subunit CENP-F_leu_zip PF10473.9 KEZ46103.1 - 0.014 15.4 5.1 0.023 14.7 4.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MIF4G_like_2 PF09090.11 KEZ46103.1 - 0.014 14.9 1.3 0.018 14.6 1.3 1.1 1 0 0 1 1 1 0 MIF4G like DASH_Spc19 PF08287.11 KEZ46103.1 - 0.051 13.5 0.1 0.051 13.5 0.1 2.0 1 1 1 2 2 2 0 Spc19 APG6_N PF17675.1 KEZ46103.1 - 2.4 8.7 8.9 10 6.6 9.1 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_60s PF00428.19 KEZ46104.1 - 8.2 7.1 12.2 12 6.6 2.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-Q PF13094.6 KEZ46105.1 - 2e-29 103.0 0.2 2e-29 103.0 0.2 2.9 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 KEZ46105.1 - 1.3 9.5 12.3 0.028 15.0 4.1 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Meth_synt_2 PF01717.18 KEZ46106.1 - 1.6e-152 507.4 0.0 1.1e-146 488.3 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KEZ46106.1 - 8.2e-118 393.5 1.3 9.4e-111 370.3 0.0 3.2 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KEZ46106.1 - 0.00036 19.8 0.0 0.004 16.4 0.0 2.2 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) YolD PF08863.10 KEZ46106.1 - 0.1 12.6 0.9 0.28 11.3 0.9 1.7 1 0 0 1 1 1 0 YolD-like protein Prefoldin_2 PF01920.20 KEZ46108.1 - 7.4e-27 93.4 11.1 1e-26 92.9 11.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KEZ46108.1 - 0.011 15.6 2.2 0.011 15.6 2.2 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF5082 PF16888.5 KEZ46108.1 - 0.05 13.9 7.4 0.069 13.4 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) PI3K_P85_iSH2 PF16454.5 KEZ46108.1 - 0.088 12.4 9.6 0.22 11.1 9.6 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 KEZ46108.1 - 0.14 12.2 4.4 0.2 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spore_III_AB PF09548.10 KEZ46108.1 - 0.35 11.0 3.8 0.56 10.3 3.7 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Prominin PF05478.11 KEZ46108.1 - 0.48 8.3 3.1 0.6 8.0 3.0 1.2 1 1 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 KEZ46108.1 - 0.66 10.6 10.0 1e+02 3.5 10.0 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PP_kinase_N PF13089.6 KEZ46108.1 - 0.74 10.2 5.8 0.26 11.6 0.4 2.1 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain DUF4337 PF14235.6 KEZ46108.1 - 1.2 9.2 10.0 0.86 9.7 5.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FlaC_arch PF05377.11 KEZ46108.1 - 4.4 7.8 9.7 0.29 11.6 1.2 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KEZ46108.1 - 9 6.2 13.0 8.5 6.2 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator CBFD_NFYB_HMF PF00808.23 KEZ46109.1 - 1.2e-05 25.5 0.0 1.3e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 KEZ46109.1 - 0.00012 22.3 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein NRIP1_repr_3 PF15689.5 KEZ46110.1 - 0.03 14.6 2.1 0.03 14.6 2.1 2.5 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 SseB_C PF14581.6 KEZ46110.1 - 0.032 14.3 3.2 0.24 11.5 0.3 2.4 2 0 0 2 2 2 0 SseB protein C-terminal domain BST2 PF16716.5 KEZ46110.1 - 0.43 11.2 8.8 0.37 11.4 0.2 2.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Gly_acyl_tr_N PF06021.11 KEZ46110.1 - 0.86 9.7 6.5 0.64 10.1 4.0 1.9 2 1 1 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Fib_alpha PF08702.10 KEZ46110.1 - 1 9.5 6.9 9.7 6.4 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 KEZ46110.1 - 2.7 8.0 25.4 0.23 11.5 1.8 3.6 2 1 2 4 4 4 0 FlxA-like protein Noelin-1 PF12308.8 KEZ46110.1 - 3.7 7.6 7.5 13 5.9 0.1 2.7 2 1 1 3 3 3 0 Neurogenesis glycoprotein DEAD PF00270.29 KEZ46111.1 - 7.9e-32 110.4 0.0 1.7e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ46111.1 - 4.4e-23 81.8 0.0 1e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KEZ46111.1 - 1.2e-21 76.7 0.1 3.3e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KEZ46111.1 - 0.0084 16.1 0.0 0.046 13.7 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RIC1 PF07064.13 KEZ46111.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 RIC1 AAA_22 PF13401.6 KEZ46111.1 - 0.13 12.5 0.1 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KEZ46111.1 - 0.49 10.1 5.2 4.2 7.1 5.2 2.5 2 0 0 2 2 2 0 AAA domain KxDL PF10241.9 KEZ46112.1 - 3.4e-32 110.6 1.7 5e-32 110.0 1.7 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein Malate_synthase PF01274.22 KEZ46112.1 - 0.11 10.8 0.9 0.13 10.5 0.9 1.0 1 0 0 1 1 1 0 Malate synthase RasGEF PF00617.19 KEZ46113.1 - 2.1e-49 168.1 0.3 4.3e-49 167.1 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KEZ46113.1 - 1.5e-11 44.4 0.2 4.6e-11 42.9 0.2 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif ANAPC4_WD40 PF12894.7 KEZ46114.1 - 4.1e-09 36.6 0.0 0.0042 17.3 0.0 4.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KEZ46114.1 - 1.3e-06 29.0 1.6 0.18 12.7 0.0 6.4 8 0 0 8 8 6 1 WD domain, G-beta repeat Abhydrolase_6 PF12697.7 KEZ46114.1 - 1.7e-06 28.8 0.0 5.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.12 KEZ46114.1 - 7.6e-06 25.9 0.0 2.7e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain PGAP1 PF07819.13 KEZ46114.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KEZ46114.1 - 0.0012 18.6 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA_22 PF13401.6 KEZ46114.1 - 0.015 15.6 0.0 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF676 PF05057.14 KEZ46114.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KEZ46114.1 - 0.053 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_helicase PF00910.22 KEZ46114.1 - 0.14 12.6 0.0 1.6 9.1 0.0 2.4 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KEZ46114.1 - 0.16 11.6 0.0 0.49 10.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KEZ46115.1 - 5.1e-47 159.6 0.0 4e-37 127.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ46115.1 - 2.6e-11 43.1 0.1 5.6e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KEZ46115.1 - 7.2e-07 29.6 0.1 0.00086 19.6 0.0 3.6 2 2 0 3 3 3 1 AAA domain CDC48_2 PF02933.17 KEZ46115.1 - 9.1e-06 25.4 0.7 0.00012 21.8 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 KEZ46115.1 - 1.4e-05 25.5 0.0 0.001 19.5 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KEZ46115.1 - 3.6e-05 23.1 0.0 0.0041 16.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 KEZ46115.1 - 0.00012 22.1 0.8 6.6 6.6 0.0 3.8 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_2 PF07724.14 KEZ46115.1 - 0.00018 21.7 0.6 0.00046 20.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KEZ46115.1 - 0.00024 21.6 0.0 0.097 13.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KEZ46115.1 - 0.00051 19.8 0.1 0.025 14.3 0.1 3.1 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KEZ46115.1 - 0.00057 19.7 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KEZ46115.1 - 0.00075 19.5 0.0 0.0035 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 KEZ46115.1 - 0.0011 19.0 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEZ46115.1 - 0.0018 18.4 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEZ46115.1 - 0.002 17.6 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KEZ46115.1 - 0.002 18.2 0.0 0.68 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEZ46115.1 - 0.0038 17.6 0.0 0.044 14.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DAP3 PF10236.9 KEZ46115.1 - 0.0047 16.1 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 KEZ46115.1 - 0.0052 17.3 0.6 0.036 14.6 0.1 2.4 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 KEZ46115.1 - 0.0056 16.2 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 1 1 P-loop containing dynein motor region ResIII PF04851.15 KEZ46115.1 - 0.011 15.8 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KEZ46115.1 - 0.02 14.6 0.4 0.099 12.4 0.0 2.3 3 1 0 3 3 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 KEZ46115.1 - 0.043 14.1 0.0 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KEZ46115.1 - 0.06 13.2 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KEZ46115.1 - 0.083 13.2 0.0 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KEZ46115.1 - 0.085 13.3 0.1 21 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KEZ46115.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KEZ46115.1 - 0.12 12.1 0.1 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KEZ46115.1 - 0.21 11.5 4.5 9.2 6.2 0.1 3.8 4 0 0 4 4 3 0 NACHT domain Parvo_NS1 PF01057.17 KEZ46115.1 - 0.22 10.6 0.0 0.45 9.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNase_PH PF01138.21 KEZ46116.1 - 6.9e-14 52.5 0.0 1.4e-13 51.4 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KEZ46116.1 - 0.088 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Cir_N PF10197.9 KEZ46117.1 - 1.7e-07 31.3 2.8 1.7e-07 31.3 2.8 5.1 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Cytochrom_C PF00034.21 KEZ46118.1 - 1e-11 45.8 0.1 1.5e-11 45.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KEZ46118.1 - 9.2e-09 35.5 2.2 3.6e-08 33.6 2.2 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KEZ46118.1 - 0.0072 16.0 2.2 0.031 14.0 2.1 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 KEZ46118.1 - 0.11 13.2 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 KEZ46118.1 - 0.17 11.5 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Snf7 PF03357.21 KEZ46120.1 - 7.2e-33 113.6 7.2 8.5e-33 113.4 7.2 1.0 1 0 0 1 1 1 1 Snf7 DUF2138 PF09909.9 KEZ46120.1 - 0.048 12.0 0.1 0.091 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Fructosamin_kin PF03881.14 KEZ46121.1 - 1e-60 205.4 0.0 1.1e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KEZ46121.1 - 0.034 14.1 0.0 0.054 13.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 KEZ46121.1 - 0.21 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase GATase_2 PF00310.21 KEZ46122.1 - 3.7e-181 602.4 0.0 5.1e-181 602.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KEZ46122.1 - 1.1e-154 515.0 0.0 1.7e-154 514.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KEZ46122.1 - 3.2e-110 368.0 0.0 1e-108 363.1 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KEZ46122.1 - 1.3e-85 285.8 1.4 2.2e-85 285.1 1.4 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KEZ46122.1 - 4e-21 75.5 0.1 2.1e-20 73.2 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KEZ46122.1 - 6.2e-21 74.3 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KEZ46122.1 - 3.2e-09 36.9 0.0 1.2e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ46122.1 - 1.6e-07 31.2 0.1 0.00044 19.9 0.0 3.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ46122.1 - 2.4e-07 31.2 0.0 6.5e-05 23.4 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEZ46122.1 - 4.2e-07 29.6 0.0 7.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KEZ46122.1 - 4.4e-05 22.4 0.6 7.1e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein FMO-like PF00743.19 KEZ46122.1 - 0.00012 20.7 0.1 0.35 9.2 0.0 2.5 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KEZ46122.1 - 0.0002 20.7 0.1 0.054 12.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KEZ46122.1 - 0.00033 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KEZ46122.1 - 0.00068 20.0 0.0 3.5 8.1 0.1 3.3 3 0 0 3 3 3 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KEZ46122.1 - 0.0015 17.7 0.4 0.0069 15.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KEZ46122.1 - 0.0023 17.2 0.0 0.0061 15.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KEZ46122.1 - 0.0027 17.0 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 KEZ46122.1 - 0.011 15.7 0.1 0.038 14.0 0.0 1.9 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 KEZ46122.1 - 0.012 15.7 0.6 5.4 7.1 0.1 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KEZ46122.1 - 0.08 12.2 0.1 5.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 KEZ46122.1 - 0.085 12.8 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding FMN_dh PF01070.18 KEZ46122.1 - 0.12 11.4 0.9 0.25 10.3 0.6 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.12 KEZ46122.1 - 0.13 11.3 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KEZ46122.1 - 0.15 11.4 0.1 0.53 9.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEZ46122.1 - 0.17 12.5 0.0 1.5 9.5 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 KEZ46122.1 - 0.2 10.8 0.0 16 4.5 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Relaxase PF03432.14 KEZ46122.1 - 0.21 11.2 2.8 0.41 10.2 2.8 1.4 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Apc15p PF05841.11 KEZ46123.1 - 1.4e-19 71.1 4.2 1.4e-19 71.1 4.2 2.1 2 1 0 2 2 2 1 Apc15p protein FluMu_N PF17891.1 KEZ46123.1 - 0.00032 20.4 1.1 0.00078 19.2 1.1 1.6 1 0 0 1 1 1 1 Mu-like prophage FluMu N-terminal domain Use1 PF09753.9 KEZ46124.1 - 0.0077 16.0 0.0 0.0077 16.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4516 PF14990.6 KEZ46124.1 - 0.21 11.3 0.3 0.41 10.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) CHZ PF09649.10 KEZ46125.1 - 3.3e-17 61.7 5.7 3.3e-17 61.7 5.7 2.8 3 1 0 3 3 3 1 Histone chaperone domain CHZ BUD22 PF09073.10 KEZ46125.1 - 4.5 6.5 22.9 5.4 6.2 22.9 1.0 1 0 0 1 1 1 0 BUD22 Cyclin PF08613.11 KEZ46127.1 - 1.5e-31 109.9 0.3 4.8e-31 108.3 0.3 2.0 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KEZ46127.1 - 0.00031 20.5 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.23 KEZ46128.1 - 3.7e-13 49.0 12.5 0.00011 22.1 0.0 9.3 11 0 0 11 11 11 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KEZ46128.1 - 6.9e-10 39.2 7.1 0.11 13.0 0.1 7.1 6 1 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 KEZ46128.1 - 1.9e-07 30.8 12.8 0.18 12.1 0.0 8.2 8 0 0 8 8 8 3 HEAT repeat V-ATPase_H_N PF03224.14 KEZ46128.1 - 1.5e-06 27.8 0.1 0.0016 17.8 0.0 3.6 3 1 0 3 3 3 2 V-ATPase subunit H HEAT_2 PF13646.6 KEZ46128.1 - 3.3e-05 24.2 14.5 0.3 11.5 0.1 6.1 6 3 0 6 6 6 3 HEAT repeats WAPL PF07814.13 KEZ46128.1 - 0.051 12.4 0.2 0.62 8.8 0.2 2.3 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin DUF3361 PF11841.8 KEZ46128.1 - 0.57 10.1 4.3 1.3 8.9 0.0 3.2 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Velvet PF11754.8 KEZ46129.1 - 4.3e-53 180.8 0.0 1.6e-34 120.0 0.0 3.7 2 2 1 3 3 3 2 Velvet factor Ank_5 PF13857.6 KEZ46130.1 - 4.9e-12 45.8 0.1 3.3e-11 43.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TIG PF01833.24 KEZ46130.1 - 5.8e-12 45.5 1.8 6.2e-12 45.4 0.3 1.9 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 KEZ46130.1 - 8.2e-10 39.2 0.0 1.9e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KEZ46130.1 - 4.3e-09 36.4 0.4 2.5e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KEZ46130.1 - 1.4e-06 28.2 0.2 0.0025 18.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KEZ46130.1 - 2.5e-06 27.9 0.6 1.3e-05 25.6 0.1 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF4118 PF13493.6 KEZ46130.1 - 0.016 15.0 0.2 0.041 13.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) Cauli_VI PF01693.16 KEZ46131.1 - 6.9e-39 131.9 9.3 6.5e-21 74.4 0.5 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KEZ46131.1 - 3.6e-37 127.7 0.6 5.7e-37 127.1 0.6 1.3 1 0 0 1 1 1 1 RNase H dCMP_cyt_deam_1 PF00383.23 KEZ46132.1 - 1.7e-09 37.5 0.0 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KEZ46132.1 - 0.0099 15.6 0.1 0.037 13.8 0.0 1.9 2 0 0 2 2 2 1 MafB19-like deaminase 6PF2K PF01591.18 KEZ46133.1 - 1.1e-66 224.4 0.0 1.7e-47 161.6 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KEZ46133.1 - 1.1e-31 110.1 0.0 1e-23 84.1 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KEZ46133.1 - 0.0003 21.0 0.0 0.0021 18.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KEZ46133.1 - 0.045 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PhoU PF01895.19 KEZ46133.1 - 0.1 13.1 0.6 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 PhoU domain Zn_clus PF00172.18 KEZ46134.1 - 4.7e-08 33.0 9.5 7.4e-08 32.4 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEZ46134.1 - 8.2e-05 21.6 0.4 0.00013 20.9 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.6 KEZ46135.1 - 1.1e-12 48.0 3.7 1.8e-12 47.4 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KEZ46135.1 - 1.3e-10 40.8 1.6 2.3e-10 40.0 1.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KEZ46135.1 - 5.1e-08 32.6 4.0 8.2e-08 32.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KEZ46135.1 - 1.8e-07 30.9 2.6 3e-07 30.2 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KEZ46135.1 - 5.6e-07 29.8 4.8 1.3e-06 28.5 4.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KEZ46135.1 - 9.5e-05 22.2 4.1 0.00017 21.3 4.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KEZ46135.1 - 0.00011 22.1 1.2 0.00017 21.5 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KEZ46135.1 - 0.0021 18.0 1.2 0.0041 17.1 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KEZ46135.1 - 0.0024 17.7 1.8 0.0039 17.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ46135.1 - 0.021 14.8 4.5 0.043 13.8 4.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.6 KEZ46135.1 - 0.06 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KEZ46135.1 - 0.13 12.1 2.8 0.23 11.3 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 KEZ46135.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 KEZ46135.1 - 0.16 12.3 1.6 0.26 11.6 1.6 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 KEZ46135.1 - 0.69 10.1 3.8 3.4 7.9 3.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KEZ46135.1 - 0.82 9.9 2.5 1.8 8.8 2.5 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 KEZ46135.1 - 0.9 9.5 3.0 1.9 8.4 2.9 1.7 1 1 0 1 1 1 0 PHD-finger Lyase_1 PF00206.20 KEZ46136.1 - 8.5e-17 61.5 0.1 1.3e-16 60.9 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KEZ46136.1 - 3.2e-15 56.4 0.0 9.9e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Skp1 PF01466.19 KEZ46136.1 - 0.3 11.3 3.0 22 5.3 0.2 3.1 2 0 0 2 2 2 0 Skp1 family, dimerisation domain CAP_GLY PF01302.25 KEZ46137.1 - 8.6e-22 76.9 1.8 1.3e-21 76.4 1.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KEZ46137.1 - 4.2e-19 68.8 0.0 7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KEZ46137.1 - 7.2e-06 25.7 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family T6_Ig_like PF18002.1 KEZ46137.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain MFS_1 PF07690.16 KEZ46138.1 - 3.3e-18 65.7 16.6 3.3e-18 65.7 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VHS PF00790.19 KEZ46139.1 - 4e-07 30.0 0.0 8.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain CFIA_Pcf11 PF11526.8 KEZ46139.1 - 6.1e-07 29.8 0.2 1.9e-06 28.3 0.2 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KEZ46139.1 - 0.00026 21.8 0.0 0.0016 19.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 KEZ46139.1 - 0.08 13.4 0.3 0.08 13.4 0.3 2.3 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-NADH-PPase PF09297.11 KEZ46139.1 - 0.11 12.2 0.8 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2_4 PF13894.6 KEZ46139.1 - 0.49 11.4 4.8 13 7.0 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KEZ46139.1 - 0.6 10.1 3.9 1.4 8.9 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 KEZ46139.1 - 0.93 9.1 8.0 0.8 9.4 2.7 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger GFO_IDH_MocA PF01408.22 KEZ46140.1 - 1.2e-14 55.2 0.1 2.3e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Myb_DNA-binding PF00249.31 KEZ46141.1 - 1.9e-11 44.0 1.1 4.5e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEZ46141.1 - 8.3e-05 22.8 0.3 0.00023 21.4 0.2 1.8 1 1 1 2 2 2 1 Myb-like DNA-binding domain Totivirus_coat PF05518.11 KEZ46141.1 - 5.1 5.0 13.8 6.7 4.6 13.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein ABC2_membrane PF01061.24 KEZ46142.1 - 9.5e-84 280.0 64.1 6.5e-43 146.6 19.9 3.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KEZ46142.1 - 4.9e-38 130.7 0.0 2.4e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KEZ46142.1 - 7e-35 118.8 3.1 2.3e-28 97.9 0.1 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KEZ46142.1 - 4.7e-14 52.8 0.0 1.1e-13 51.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 KEZ46142.1 - 1.7e-05 24.8 0.9 0.0035 17.3 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase AAA_33 PF13671.6 KEZ46142.1 - 2.8e-05 24.3 1.8 0.0017 18.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KEZ46142.1 - 0.00022 21.8 0.0 0.0026 18.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KEZ46142.1 - 0.00029 20.5 0.1 0.029 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ46142.1 - 0.0004 20.8 0.1 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KEZ46142.1 - 0.0017 18.0 0.5 0.053 13.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KEZ46142.1 - 0.0029 17.1 0.0 1.3 8.4 0.0 3.3 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 KEZ46142.1 - 0.0047 16.9 0.8 1.7 8.5 0.1 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 KEZ46142.1 - 0.01 15.4 0.5 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KEZ46142.1 - 0.012 15.4 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TrpP PF17099.5 KEZ46142.1 - 0.013 15.2 0.3 0.013 15.2 0.3 2.1 2 0 0 2 2 2 0 Tryptophan transporter TrpP AAA_30 PF13604.6 KEZ46142.1 - 0.02 14.6 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KEZ46142.1 - 0.029 14.4 0.0 8.2 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KEZ46142.1 - 0.034 14.4 0.3 1.7 8.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KEZ46142.1 - 0.074 13.4 0.1 13 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KEZ46142.1 - 0.081 13.3 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KEZ46142.1 - 0.087 13.3 0.2 2 8.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain DUF2946 PF11162.8 KEZ46142.1 - 0.5 11.1 1.7 2 9.1 1.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) RPN6_N PF18055.1 KEZ46143.1 - 7.6e-46 155.3 3.9 7.6e-46 155.3 3.9 2.3 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KEZ46143.1 - 3.1e-20 72.6 1.1 1.6e-19 70.4 0.1 2.6 3 1 0 3 3 2 1 PCI domain RPN6_C_helix PF18503.1 KEZ46143.1 - 5e-10 38.9 0.3 1.1e-09 37.8 0.3 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 KEZ46143.1 - 2.6e-05 23.8 4.5 2.6e-05 23.8 4.5 2.4 2 1 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KEZ46143.1 - 7.8e-05 22.4 3.3 1.2 9.4 0.5 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ46143.1 - 0.00022 21.5 20.3 0.0097 16.2 1.6 5.6 3 2 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.9 KEZ46143.1 - 0.00094 18.8 0.2 0.00094 18.8 0.2 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_2 PF07719.17 KEZ46143.1 - 0.0029 17.6 6.9 30 5.0 0.0 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat DUF410 PF04190.13 KEZ46143.1 - 0.0099 15.7 2.8 0.03 14.1 0.2 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF410) TPR_14 PF13428.6 KEZ46143.1 - 0.02 15.6 11.0 3.4 8.7 0.0 6.1 4 3 2 6 6 6 0 Tetratricopeptide repeat ATP13 PF12921.7 KEZ46143.1 - 0.021 14.7 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase expression ParB PF08775.10 KEZ46143.1 - 0.035 14.6 0.5 0.035 14.6 0.5 2.2 3 0 0 3 3 2 0 ParB family TPR_19 PF14559.6 KEZ46143.1 - 0.062 13.8 17.6 0.28 11.7 0.1 5.6 5 2 1 6 6 5 0 Tetratricopeptide repeat Med2 PF11214.8 KEZ46143.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.9 3 0 0 3 3 3 0 Mediator complex subunit 2 TPR_16 PF13432.6 KEZ46143.1 - 0.13 12.9 10.6 3.6 8.3 0.2 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ46143.1 - 0.21 12.3 2.2 1.1 10.1 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ46143.1 - 0.3 11.0 7.7 10 6.1 0.1 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat YfdX PF10938.8 KEZ46143.1 - 1.6 8.6 8.0 0.59 10.0 0.2 3.4 1 1 1 3 3 3 0 YfdX protein DUF4398 PF14346.6 KEZ46143.1 - 4.1 8.1 9.5 12 6.6 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) Mito_carr PF00153.27 KEZ46144.1 - 9e-53 176.2 4.7 1.6e-16 60.0 0.8 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 KEZ46144.1 - 0.081 12.9 0.1 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 UcrQ family HMD PF03201.16 KEZ46144.1 - 0.12 12.7 0.0 7.9 6.8 0.0 2.7 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase HTH_21 PF13276.6 KEZ46144.1 - 0.14 12.3 0.1 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 HTH-like domain Mak10 PF04112.13 KEZ46145.1 - 4.9e-32 110.8 1.8 1.4e-28 99.5 0.0 3.8 3 1 0 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 KEZ46146.1 - 1.5e-23 82.5 2.4 1.5e-23 82.5 2.4 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain DUF2184 PF09950.9 KEZ46146.1 - 0.0043 16.5 0.3 0.0047 16.3 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2184) RGS PF00615.19 KEZ46147.1 - 0.11 12.7 0.2 1.4 9.2 0.0 2.4 3 0 0 3 3 3 0 Regulator of G protein signaling domain HGTP_anticodon PF03129.20 KEZ46148.1 - 2.9e-21 75.4 0.0 8.6e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KEZ46148.1 - 1.7e-07 31.4 0.0 1.3e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_72 PF03198.14 KEZ46149.1 - 6.7e-74 249.0 1.0 1.3e-61 208.6 0.6 2.2 1 1 1 2 2 2 2 Glucanosyltransferase Cellulase PF00150.18 KEZ46149.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 KEZ46149.1 - 0.16 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain adh_short PF00106.25 KEZ46151.1 - 1.2e-37 129.3 0.2 1.6e-37 128.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ46151.1 - 1e-29 103.8 0.0 1.4e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ46151.1 - 4.2e-10 39.8 4.0 2.1e-09 37.6 4.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KEZ46151.1 - 0.0005 19.6 0.1 0.00078 19.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FtsJ PF01728.19 KEZ46151.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase HI0933_like PF03486.14 KEZ46151.1 - 0.087 11.5 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Sof1 PF04158.14 KEZ46152.1 - 2e-30 104.9 14.5 3.5e-30 104.1 14.5 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KEZ46152.1 - 1.3e-27 95.5 13.0 1.3e-05 25.9 1.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ46152.1 - 2.4e-09 37.4 2.0 0.064 13.6 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ46152.1 - 0.00069 18.7 0.1 0.18 10.8 0.0 3.3 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein XPG_I PF00867.18 KEZ46152.1 - 0.22 11.9 1.1 0.76 10.2 0.0 2.3 2 0 0 2 2 2 0 XPG I-region RNA_pol_A_bac PF01000.26 KEZ46153.1 - 2.7e-32 111.4 0.0 5.6e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KEZ46153.1 - 1.3e-17 62.9 0.0 1.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HeLo PF14479.6 KEZ46154.1 - 3.2e-22 79.4 0.0 5.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation HET PF06985.11 KEZ46154.1 - 1e-18 68.1 0.0 6.1e-18 65.6 0.0 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Cyt-b5 PF00173.28 KEZ46154.1 - 0.13 12.4 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain 4F5 PF04419.14 KEZ46155.1 - 3.7e-07 30.9 7.1 3.7e-07 30.9 7.1 3.2 3 1 1 4 4 4 1 4F5 protein family Cu_bind_like PF02298.17 KEZ46156.1 - 0.2 11.7 0.1 0.57 10.2 0.1 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain SMN PF06003.12 KEZ46157.1 - 1.7 7.9 9.7 0.76 9.0 2.5 2.6 1 1 2 3 3 3 0 Survival motor neuron protein (SMN) RRM_1 PF00076.22 KEZ46158.1 - 2.9e-15 55.8 0.0 2.9e-15 55.8 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KEZ46158.1 - 0.01 15.8 0.1 0.025 14.6 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KEZ46158.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KEZ46158.1 - 0.15 12.0 0.8 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 RL domain GRAB PF10375.9 KEZ46159.1 - 1.2e-08 34.4 0.1 2.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.11 KEZ46159.1 - 0.00023 20.1 57.5 0.018 14.0 31.3 2.8 1 1 2 3 3 3 3 Spc7 kinetochore protein Golgin_A5 PF09787.9 KEZ46159.1 - 0.0017 17.9 56.0 0.033 13.7 27.6 3.3 1 1 3 4 4 4 2 Golgin subfamily A member 5 DUF1664 PF07889.12 KEZ46159.1 - 0.0018 18.3 31.5 0.36 10.9 1.5 4.2 1 1 4 5 5 5 4 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 KEZ46159.1 - 0.0019 18.2 67.1 0.022 14.8 12.7 4.7 2 2 2 4 4 4 3 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KEZ46159.1 - 0.002 18.2 62.5 0.039 14.0 31.2 3.6 2 2 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 KEZ46159.1 - 0.0042 16.7 50.8 0.019 14.5 16.7 3.4 1 1 2 3 3 3 2 Intermediate filament protein Baculo_PEP_C PF04513.12 KEZ46159.1 - 0.0075 16.3 1.9 0.0075 16.3 1.9 3.5 1 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 KEZ46159.1 - 0.011 16.0 37.2 0.77 10.1 6.3 5.0 1 1 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cast PF10174.9 KEZ46159.1 - 0.017 13.4 45.8 0.023 13.0 45.8 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone NPV_P10 PF05531.12 KEZ46159.1 - 0.02 15.4 26.4 0.023 15.2 1.8 4.7 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KEZ46159.1 - 0.022 14.1 55.9 0.13 11.6 13.8 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KEZ46159.1 - 0.026 14.8 62.0 1.2 9.3 24.3 4.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TRAF_BIRC3_bd PF16673.5 KEZ46159.1 - 0.037 13.8 0.7 0.037 13.8 0.7 5.1 4 2 2 6 6 6 0 TNF receptor-associated factor BIRC3 binding domain Lectin_N PF03954.14 KEZ46159.1 - 0.074 12.8 28.1 0.14 11.9 3.5 3.7 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF641 PF04859.12 KEZ46159.1 - 0.086 13.2 36.1 1.9 8.9 6.0 3.7 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF3584 PF12128.8 KEZ46159.1 - 0.1 10.1 52.7 0.13 9.8 51.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) FH2 PF02181.23 KEZ46159.1 - 0.11 11.6 36.2 0.04 13.0 6.4 3.3 1 1 2 3 3 3 0 Formin Homology 2 Domain SNARE PF05739.19 KEZ46159.1 - 0.19 11.7 7.4 7.2 6.7 0.2 3.7 3 0 0 3 3 3 0 SNARE domain HMMR_N PF15905.5 KEZ46159.1 - 0.28 10.6 55.3 3.4 7.0 22.7 3.4 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 KEZ46159.1 - 0.32 11.2 32.7 1.1 9.5 5.7 3.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 KEZ46159.1 - 0.36 9.4 43.0 0.12 11.0 26.4 2.3 1 1 1 2 2 2 0 AAA domain APG6_N PF17675.1 KEZ46159.1 - 0.44 11.1 65.6 1.6 9.3 19.5 3.8 2 2 1 3 3 3 0 Apg6 coiled-coil region T7SS_ESX_EspC PF10824.8 KEZ46159.1 - 0.63 10.5 13.2 0.31 11.5 3.4 3.5 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm FAM184 PF15665.5 KEZ46159.1 - 0.79 9.5 57.4 0.33 10.7 18.9 3.0 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B Rootletin PF15035.6 KEZ46159.1 - 0.98 9.4 49.4 0.77 9.8 29.2 2.9 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HicB_lk_antitox PF15919.5 KEZ46159.1 - 0.99 9.5 5.1 4.1 7.5 0.9 2.5 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system FUSC PF04632.12 KEZ46159.1 - 1.1 7.7 29.0 0.096 11.2 10.3 2.6 1 1 2 3 3 3 0 Fusaric acid resistance protein family DUF4407 PF14362.6 KEZ46159.1 - 1.9 7.8 41.0 0.41 10.0 14.7 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 KEZ46159.1 - 2.2 8.6 31.4 4.6 7.5 5.9 4.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF2959 PF11172.8 KEZ46159.1 - 2.6 8.2 30.5 1.6 8.9 16.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) KASH_CCD PF14662.6 KEZ46159.1 - 3 7.6 62.0 2.1 8.1 15.2 3.3 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH YscO PF07321.12 KEZ46159.1 - 3.7 7.5 64.4 0.37 10.7 10.5 4.3 2 2 2 4 4 4 0 Type III secretion protein YscO Uso1_p115_C PF04871.13 KEZ46159.1 - 4.1 7.8 58.3 6.4 7.2 16.8 3.7 1 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prominin PF05478.11 KEZ46159.1 - 5.4 4.9 26.5 3.6 5.4 12.7 2.2 1 1 1 2 2 2 0 Prominin Exonuc_VII_L PF02601.15 KEZ46159.1 - 5.8 6.4 39.7 3.2 7.2 19.0 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit Mod_r PF07200.13 KEZ46159.1 - 6.2 6.9 49.7 1.9 8.6 9.6 4.8 1 1 3 4 4 4 0 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 KEZ46159.1 - 6.9 7.1 55.3 1.6 9.1 28.2 3.0 1 1 1 2 2 2 0 Fez1 DUF4618 PF15397.6 KEZ46159.1 - 9.2 5.6 42.9 1.7 8.0 9.8 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) IFT57 PF10498.9 KEZ46159.1 - 9.3 5.1 46.5 22 3.9 18.6 2.4 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF948 PF06103.11 KEZ46159.1 - 9.8 6.5 21.8 22 5.4 0.9 4.3 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MLTD_N PF06474.12 KEZ46160.1 - 0.078 13.2 0.9 0.078 13.2 0.9 2.1 2 0 0 2 2 2 0 MltD lipid attachment motif CHD5 PF04420.14 KEZ46161.1 - 9.6e-57 191.3 1.7 1.2e-56 191.0 1.7 1.1 1 0 0 1 1 1 1 CHD5-like protein FbpA PF05833.11 KEZ46161.1 - 0.0024 16.7 1.0 0.003 16.4 1.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) TMEM247 PF15444.6 KEZ46161.1 - 0.012 15.7 0.2 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 LapA_dom PF06305.11 KEZ46161.1 - 0.03 14.1 0.3 0.03 14.1 0.3 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain FtsL PF04999.13 KEZ46161.1 - 0.082 12.9 2.1 0.14 12.1 1.4 1.9 1 1 0 1 1 1 0 Cell division protein FtsL EMC3_TMCO1 PF01956.16 KEZ46161.1 - 0.47 10.2 3.2 1.4 8.6 3.2 1.8 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Asp PF00026.23 KEZ46162.1 - 1.4e-67 228.4 1.2 1.8e-67 228.0 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ46162.1 - 4.8e-11 43.2 3.6 3.5e-05 24.1 0.1 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEZ46162.1 - 0.00016 22.2 0.7 0.072 13.7 0.2 3.2 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KEZ46162.1 - 0.011 16.3 0.0 0.16 12.5 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KEZ46162.1 - 0.039 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Aa_trans PF01490.18 KEZ46163.1 - 1.1e-73 248.4 26.2 1.3e-73 248.1 26.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ras PF00071.22 KEZ46164.1 - 3.9e-55 185.9 0.0 4.5e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ46164.1 - 8.3e-22 77.7 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ46164.1 - 1.7e-07 30.8 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KEZ46164.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KEZ46164.1 - 0.06 12.5 0.1 0.57 9.3 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KEZ46164.1 - 0.2 11.0 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Syntaxin-6_N PF09177.11 KEZ46165.1 - 0.047 14.3 3.8 0.24 12.0 0.1 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal IKI3 PF04762.12 KEZ46166.1 - 2.1e-291 969.3 0.0 4.5e-291 968.2 0.0 1.5 1 1 0 1 1 1 1 IKI3 family TPR_1 PF00515.28 KEZ46166.1 - 0.099 12.5 1.4 0.66 9.9 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HIRA_B PF09453.10 KEZ46166.1 - 0.12 12.2 2.0 3.1 7.7 0.2 2.5 2 0 0 2 2 2 0 HIRA B motif Hpt PF01627.23 KEZ46167.1 - 3.5e-12 46.4 0.0 2.2e-11 43.8 0.0 2.2 1 1 1 2 2 2 1 Hpt domain DUF4564 PF15169.6 KEZ46167.1 - 0.043 13.5 3.3 0.064 13.0 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) Nucleolin_bd PF16725.5 KEZ46167.1 - 0.077 12.7 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Nucleolin binding domain SGT1 PF07093.11 KEZ46167.1 - 0.082 11.3 5.8 0.082 11.3 5.8 1.1 1 0 0 1 1 1 0 SGT1 protein RP-C_C PF11800.8 KEZ46167.1 - 0.24 11.5 6.4 0.61 10.2 6.2 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region GCIP PF13324.6 KEZ46167.1 - 0.5 9.9 8.9 0.86 9.2 8.9 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sporozoite_P67 PF05642.11 KEZ46167.1 - 0.56 8.2 8.9 0.69 7.9 8.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 KEZ46167.1 - 0.7 8.0 18.9 0.81 7.8 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 KEZ46167.1 - 0.8 8.2 8.0 1.1 7.7 8.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Paf1 PF03985.13 KEZ46167.1 - 1.2 8.1 14.2 1.9 7.4 14.2 1.3 1 0 0 1 1 1 0 Paf1 PTPRCAP PF15713.5 KEZ46167.1 - 1.5 9.1 17.8 2.7 8.3 17.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 KEZ46167.1 - 2.3 6.4 16.5 3 6.0 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DHHW PF14286.6 KEZ46167.1 - 5.5 6.2 6.8 7.8 5.7 6.8 1.2 1 0 0 1 1 1 0 DHHW protein DUF4611 PF15387.6 KEZ46167.1 - 6.4 7.1 16.0 0.7 10.2 10.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) SAPS PF04499.15 KEZ46167.1 - 8.7 5.0 8.9 9.6 4.9 8.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.12 KEZ46167.1 - 8.8 4.5 12.3 14 3.8 12.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Spc7 PF08317.11 KEZ46168.1 - 0.03 13.2 6.0 0.054 12.4 6.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 KEZ46168.1 - 0.1 12.6 10.2 2.8 8.0 0.1 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 KEZ46168.1 - 0.13 11.4 2.0 0.25 10.4 2.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3150 PF11348.8 KEZ46168.1 - 0.13 11.5 3.6 0.078 12.2 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) ERM PF00769.19 KEZ46168.1 - 0.15 11.9 7.9 0.27 11.0 7.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Lebercilin PF15619.6 KEZ46168.1 - 0.19 11.4 11.2 0.27 10.9 3.4 2.8 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Csm1_N PF18504.1 KEZ46168.1 - 0.41 11.0 8.2 0.63 10.4 0.1 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain FAM184 PF15665.5 KEZ46168.1 - 0.49 10.1 8.6 1.6 8.5 6.6 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B PKcGMP_CC PF16808.5 KEZ46168.1 - 0.75 9.7 7.9 7.5 6.5 0.2 2.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NYD-SP28 PF14772.6 KEZ46168.1 - 1.4 9.1 8.1 0.062 13.3 0.7 2.5 3 0 0 3 3 3 0 Sperm tail HSP70 PF00012.20 KEZ46169.1 - 3.3e-09 35.5 0.1 2.2e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 KEZ46169.1 - 0.0081 16.6 0.1 0.21 12.0 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA Pkinase PF00069.25 KEZ46170.1 - 2.5e-56 191.0 0.0 3.6e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46170.1 - 1.3e-31 109.9 0.0 4.9e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KEZ46170.1 - 0.0055 15.7 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KEZ46170.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KEZ46170.1 - 0.12 11.8 0.2 0.22 10.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stc1 PF12898.7 KEZ46171.1 - 4.8e-17 62.3 0.5 1.3e-16 60.9 0.5 1.7 1 0 0 1 1 1 1 Stc1 domain BCDHK_Adom3 PF10436.9 KEZ46172.1 - 6.2e-73 244.0 0.0 9e-73 243.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KEZ46172.1 - 4.6e-13 49.7 0.0 1.2e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEZ46172.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4349 PF14257.6 KEZ46173.1 - 0.00098 18.6 2.9 0.00098 18.6 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) CENP-F_leu_zip PF10473.9 KEZ46173.1 - 0.054 13.5 6.0 0.03 14.3 3.5 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KEZ46173.1 - 0.54 9.1 7.4 0.71 8.7 5.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.12 KEZ46173.1 - 0.98 9.9 3.8 53 4.4 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 KEZ46173.1 - 1.4 7.3 3.1 1.6 7.2 2.2 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 KEZ46173.1 - 1.7 8.7 3.5 2.7 8.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 KEZ46173.1 - 9.6 7.0 7.6 0.54 11.0 1.4 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Sugar_tr PF00083.24 KEZ46174.1 - 1.3e-81 274.8 17.7 2.1e-81 274.1 17.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ46174.1 - 8.1e-12 44.7 39.8 1.1e-11 44.3 25.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Macoilin PF09726.9 KEZ46175.1 - 2.3 6.7 6.3 3 6.3 6.3 1.2 1 0 0 1 1 1 0 Macoilin family Pyridoxal_deC PF00282.19 KEZ46176.1 - 2.5e-15 56.1 0.0 3.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KEZ46176.1 - 0.0001 21.4 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KEZ46176.1 - 0.086 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.12 KEZ46177.1 - 5.8e-68 229.2 0.0 7e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Proteasome PF00227.26 KEZ46178.1 - 8.6e-58 195.0 0.0 9.4e-34 116.6 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KEZ46178.1 - 1.8e-10 40.3 0.2 5.1e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 KEZ46178.1 - 0.12 11.0 0.3 8.5 5.0 0.0 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RCC1_2 PF13540.6 KEZ46179.1 - 5e-16 58.0 2.4 2.5e-05 24.0 0.1 4.7 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 KEZ46179.1 - 3.4e-08 34.0 0.3 0.0034 18.0 0.1 4.8 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ribonuclease_3 PF00636.26 KEZ46180.1 - 3.9e-36 123.8 0.0 3e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KEZ46180.1 - 6.5e-23 80.7 0.0 2.8e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KEZ46180.1 - 2.5e-19 69.7 0.0 4.6e-07 30.0 0.0 3.7 3 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.31 KEZ46180.1 - 1.5e-15 57.5 0.0 7e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ46180.1 - 1.9e-08 34.5 0.0 0.0044 17.0 0.1 2.6 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 KEZ46180.1 - 3e-08 33.6 0.1 0.0026 17.5 0.0 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase DEAD_2 PF06733.15 KEZ46180.1 - 0.0032 17.1 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 AAA_22 PF13401.6 KEZ46180.1 - 0.023 14.9 0.0 0.098 12.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Rgp1 PF08737.10 KEZ46181.1 - 2.7e-156 520.9 0.0 5.3e-156 520.0 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 KEZ46181.1 - 0.0063 16.6 0.0 0.023 14.8 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KEZ46181.1 - 0.025 15.0 0.0 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain tRNA-synt_2d PF01409.20 KEZ46182.1 - 6.1e-48 163.4 0.3 5.4e-25 88.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KEZ46182.1 - 1.8e-26 92.4 0.0 5.8e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Herpes_UL82_83 PF05784.11 KEZ46182.1 - 0.012 14.5 0.1 0.021 13.7 0.1 1.4 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus tRNA-synt_2 PF00152.20 KEZ46182.1 - 0.025 13.7 0.1 0.082 12.0 0.0 1.8 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Mito_carr PF00153.27 KEZ46183.1 - 3.6e-43 145.4 8.0 5.6e-16 58.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clathrin PF00637.20 KEZ46184.1 - 3.1e-24 85.5 3.9 1.9e-22 79.7 2.4 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 KEZ46184.1 - 4e-21 75.0 0.1 9.4e-21 73.8 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KEZ46184.1 - 4.9e-07 29.7 4.7 1.2e-06 28.5 4.7 1.7 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KEZ46184.1 - 2.1e-05 24.2 3.9 4.9e-05 23.1 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KEZ46184.1 - 3.5e-05 23.7 3.4 7.1e-05 22.7 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 KEZ46184.1 - 0.004 16.8 0.1 0.004 16.8 0.1 2.1 3 0 0 3 3 2 1 TPR repeat zf-rbx1 PF12678.7 KEZ46184.1 - 0.0046 17.2 2.6 0.011 16.0 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEZ46184.1 - 0.017 15.4 4.0 0.017 15.4 4.0 1.8 2 0 0 2 2 1 0 Ring finger domain TPR_14 PF13428.6 KEZ46184.1 - 0.021 15.6 0.7 43 5.3 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 KEZ46184.1 - 0.037 13.9 2.4 0.1 12.5 2.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ46184.1 - 0.098 12.7 4.8 0.15 12.1 3.6 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Curto_V2 PF07325.11 KEZ46184.1 - 0.38 10.6 1.5 1.3 8.9 0.2 2.2 2 0 0 2 2 2 0 Curtovirus V2 protein zf-ANAPC11 PF12861.7 KEZ46184.1 - 0.38 10.8 1.4 1 9.4 1.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_19 PF14559.6 KEZ46184.1 - 2.3 8.8 11.0 0.5 10.9 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 KEZ46184.1 - 2.8 7.8 4.6 9.1 6.1 4.6 2.0 1 0 0 1 1 1 0 RING-like zinc finger ANAPC3 PF12895.7 KEZ46184.1 - 4.8 7.5 8.8 66 3.8 1.3 3.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Na_Ca_ex PF01699.24 KEZ46185.1 - 1e-19 71.0 23.7 3.2e-14 53.2 8.0 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KEZ46185.1 - 2.5e-16 60.1 15.9 2.5e-16 60.1 15.9 4.2 4 0 0 4 4 4 1 Inner membrane component domain AAA PF00004.29 KEZ46186.1 - 7.6e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ46186.1 - 2.2e-14 52.9 0.0 4.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KEZ46186.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEZ46186.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KEZ46186.1 - 2.6e-06 27.3 4.2 6.9e-06 25.9 4.2 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KEZ46186.1 - 4.3e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEZ46186.1 - 2.5e-05 24.6 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KEZ46186.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KEZ46186.1 - 0.00065 20.2 0.0 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KEZ46186.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KEZ46186.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEZ46186.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KEZ46186.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KEZ46186.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KEZ46186.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 KEZ46186.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KEZ46186.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KEZ46186.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KEZ46186.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Prot_ATP_OB_N PF17758.1 KEZ46186.1 - 0.024 14.3 0.4 0.089 12.5 0.4 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_7 PF12775.7 KEZ46186.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KEZ46186.1 - 0.029 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KEZ46186.1 - 0.032 13.9 0.0 0.1 12.3 0.0 1.8 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 KEZ46186.1 - 0.035 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KEZ46186.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KEZ46186.1 - 0.053 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 KEZ46186.1 - 0.054 13.6 1.0 0.13 12.4 1.0 1.6 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 KEZ46186.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KEZ46186.1 - 0.1 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 KEZ46186.1 - 0.17 12.2 0.1 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Y_phosphatase PF00102.27 KEZ46187.1 - 1.6e-57 194.8 0.0 3.2e-31 108.7 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 KEZ46187.1 - 2.6e-13 50.4 0.0 6.5e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 KEZ46187.1 - 0.032 14.0 0.3 0.074 12.9 0.3 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KEZ46187.1 - 0.13 12.2 1.0 0.27 11.2 1.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family ERAP1_C PF11838.8 KEZ46188.1 - 8e-86 288.4 0.0 3.9e-85 286.2 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KEZ46188.1 - 6.8e-80 267.7 4.3 1e-79 267.1 4.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KEZ46188.1 - 8.3e-49 166.3 0.2 2.1e-48 165.0 0.2 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 KEZ46188.1 - 0.65 10.0 3.2 0.98 9.4 0.4 2.6 3 1 0 3 3 3 0 Protein of unknown function DUF45 PIGA PF08288.12 KEZ46189.1 - 2.7e-46 156.1 2.4 6.6e-46 154.8 0.6 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KEZ46189.1 - 9.4e-28 96.9 0.0 1.5e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ46189.1 - 3.4e-25 89.0 0.8 5.8e-25 88.2 0.8 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KEZ46189.1 - 4.7e-24 85.3 0.0 1e-23 84.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KEZ46189.1 - 3.5e-09 37.3 0.0 6.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ46189.1 - 7.8e-05 23.0 0.0 0.00019 21.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 KEZ46189.1 - 0.00017 21.7 0.1 0.00027 21.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 KEZ46189.1 - 0.086 12.5 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Asp PF00026.23 KEZ46190.1 - 1e-35 123.7 0.0 7.7e-35 120.8 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ46190.1 - 6.3e-05 23.3 0.1 0.04 14.2 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEZ46190.1 - 0.11 13.2 0.1 11 6.7 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease CENP-Q PF13094.6 KEZ46191.1 - 0.002 18.3 0.8 0.0031 17.7 0.8 1.3 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit TACC_C PF05010.14 KEZ46191.1 - 0.0029 17.4 0.3 0.0045 16.8 0.3 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 KEZ46191.1 - 0.0051 17.4 0.3 0.0051 17.4 0.3 1.8 2 0 0 2 2 2 1 SlyX ABC_tran_CTD PF16326.5 KEZ46191.1 - 0.0071 16.6 0.7 0.025 14.8 0.4 1.9 1 1 1 2 2 2 1 ABC transporter C-terminal domain PspA_IM30 PF04012.12 KEZ46191.1 - 0.012 15.2 0.9 0.02 14.5 0.9 1.2 1 0 0 1 1 1 0 PspA/IM30 family DUF4686 PF15742.5 KEZ46191.1 - 0.013 14.6 0.2 0.019 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF16 PF01519.16 KEZ46191.1 - 0.013 15.9 0.6 0.019 15.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Tropomyosin PF00261.20 KEZ46191.1 - 0.014 14.8 1.8 0.023 14.0 1.8 1.3 1 0 0 1 1 1 0 Tropomyosin DHR10 PF18595.1 KEZ46191.1 - 0.018 15.1 1.4 0.03 14.4 1.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain SKA1 PF07160.12 KEZ46191.1 - 0.033 14.0 0.4 0.039 13.8 0.4 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Sugarporin_N PF11471.8 KEZ46191.1 - 0.034 14.1 2.4 0.06 13.3 2.4 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension KxDL PF10241.9 KEZ46191.1 - 0.039 14.2 0.7 0.081 13.2 0.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein ATG16 PF08614.11 KEZ46191.1 - 0.058 13.6 1.5 0.058 13.6 1.5 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Tup_N PF08581.10 KEZ46191.1 - 0.073 13.4 1.7 1.6 9.0 2.3 2.2 1 1 1 2 2 2 0 Tup N-terminal TMF_DNA_bd PF12329.8 KEZ46191.1 - 0.083 12.9 2.1 0.15 12.1 2.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 KEZ46191.1 - 0.13 12.5 2.8 0.23 11.7 2.8 1.4 1 0 0 1 1 1 0 Haemolysin XhlA PHO4 PF01384.20 KEZ46192.1 - 7.6e-115 383.5 15.7 8.7e-115 383.4 15.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF1707 PF08044.11 KEZ46192.1 - 0.072 13.2 0.8 0.16 12.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Glyco_hydro_31 PF01055.26 KEZ46193.1 - 1.9e-63 215.2 2.2 4e-63 214.1 2.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Trypan_PARP PF05887.11 KEZ46193.1 - 1.1e-06 28.6 441.5 0.0066 16.4 60.3 7.9 1 1 4 5 5 5 2 Procyclic acidic repetitive protein (PARP) Striatin PF08232.12 KEZ46195.1 - 9.2e-37 127.0 3.1 2.4e-36 125.7 3.1 1.8 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 KEZ46195.1 - 3.9e-25 87.6 24.3 6.3e-05 23.7 0.3 8.5 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ46195.1 - 0.00013 22.2 0.0 14 6.1 0.0 4.8 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4482 PF14818.6 KEZ46195.1 - 0.0068 17.3 3.3 0.017 16.0 3.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) CALCOCO1 PF07888.11 KEZ46195.1 - 0.05 12.5 6.8 0.071 12.0 6.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Ge1_WD40 PF16529.5 KEZ46195.1 - 0.057 12.4 0.0 0.58 9.1 0.0 2.5 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_N_2 PF16884.5 KEZ46195.1 - 0.079 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase YscO-like PF16789.5 KEZ46195.1 - 0.089 12.8 3.8 0.15 12.1 3.8 1.3 1 0 0 1 1 1 0 YscO-like protein Med6 PF04934.14 KEZ46195.1 - 0.092 12.5 1.0 0.17 11.7 1.0 1.4 1 0 0 1 1 1 0 MED6 mediator sub complex component Cytochrom_D1 PF02239.16 KEZ46195.1 - 0.094 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain HemX PF04375.14 KEZ46195.1 - 1.1 8.4 7.2 1.8 7.8 7.2 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase XPA_C PF05181.12 KEZ46196.1 - 8.4e-26 89.7 3.6 1.9e-25 88.6 3.6 1.6 1 0 0 1 1 1 1 XPA protein C-terminus Endonuc_Holl PF10107.9 KEZ46196.1 - 0.066 13.1 0.7 0.26 11.1 0.7 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase XPA_N PF01286.18 KEZ46196.1 - 0.34 11.0 13.2 0.11 12.5 6.8 2.4 2 0 0 2 2 2 0 XPA protein N-terminal C1_1 PF00130.22 KEZ46196.1 - 4.7 7.2 7.4 8.4 6.4 4.3 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CBP4 PF07960.11 KEZ46196.1 - 5.4 6.9 7.6 3.6 7.4 0.3 2.5 2 0 0 2 2 2 0 CBP4 Pho88 PF10032.9 KEZ46197.1 - 3e-76 254.7 0.0 3.4e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ribosomal_L3 PF00297.22 KEZ46198.1 - 2.2e-180 599.5 9.0 2.5e-180 599.3 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 KEZ46199.1 - 4.4e-54 178.2 26.1 7.8e-08 31.8 0.0 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ46199.1 - 3.6e-47 154.7 18.9 2.3e-05 24.1 1.1 10.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46199.1 - 3.5e-35 117.2 18.9 3.5e-06 26.8 0.0 10.6 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ46199.1 - 7.5e-30 101.2 20.4 0.00073 19.8 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46199.1 - 1.1e-27 94.3 7.4 0.00039 21.0 0.0 8.6 3 2 4 8 8 8 8 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46199.1 - 2.8e-24 85.4 14.6 0.00019 21.9 0.1 6.9 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ46199.1 - 7.2e-22 76.5 14.8 0.00082 19.9 0.0 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ46199.1 - 2.4e-21 75.1 33.8 3.9e-06 26.4 0.2 9.6 5 4 5 10 10 10 6 TPR repeat TPR_16 PF13432.6 KEZ46199.1 - 2.8e-21 75.8 19.8 0.00024 21.7 0.3 7.2 4 3 5 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ46199.1 - 1.1e-20 73.6 19.1 2.3e-05 24.6 0.5 7.3 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ46199.1 - 6.6e-17 60.2 10.9 0.011 15.8 0.1 9.0 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ46199.1 - 1.5e-16 60.3 9.8 0.0014 18.8 0.1 6.5 1 1 5 7 7 7 7 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ46199.1 - 7.6e-12 45.0 9.9 0.007 15.6 1.7 4.9 1 1 3 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ46199.1 - 2.1e-11 43.9 12.3 4.1e-09 36.5 2.0 3.6 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KEZ46199.1 - 3e-08 33.6 6.2 0.0011 18.7 0.0 4.9 3 2 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 KEZ46199.1 - 3.7e-05 24.0 3.9 0.43 10.9 0.1 4.0 4 1 1 5 5 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEZ46199.1 - 0.0049 16.9 0.7 1.9 8.6 0.1 4.2 5 0 0 5 5 3 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 KEZ46199.1 - 0.0078 15.3 2.2 2.3 7.1 0.0 3.0 2 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 KEZ46199.1 - 0.01 16.3 0.1 0.01 16.3 0.1 3.6 4 0 0 4 4 3 0 Bacterial transcriptional activator domain DUF2225 PF09986.9 KEZ46199.1 - 0.042 13.6 3.1 1.6 8.4 0.0 3.1 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 KEZ46199.1 - 0.16 11.3 15.2 2.1 7.7 0.2 4.4 1 1 3 4 4 4 0 Soluble NSF attachment protein, SNAP DUF1018 PF06252.12 KEZ46199.1 - 0.56 11.2 2.9 1.6 9.7 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1018) DUF1751 PF08551.10 KEZ46200.1 - 7.7e-28 97.0 5.6 7.7e-28 97.0 5.6 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KEZ46200.1 - 0.00079 19.5 11.7 0.0015 18.5 11.7 1.4 1 0 0 1 1 1 1 Rhomboid family WD40 PF00400.32 KEZ46201.1 - 3.9e-11 43.3 9.8 0.0035 18.2 0.0 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ46201.1 - 1.4e-07 31.7 0.5 0.022 15.0 0.1 5.1 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KEZ46201.1 - 8.1e-07 28.8 0.1 1.5e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 LisH NuiA PF07924.11 KEZ46202.1 - 0.0002 21.7 0.0 0.0039 17.6 0.0 2.1 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Chorismate_bind PF00425.18 KEZ46203.1 - 2.3e-91 306.0 0.0 2.8e-90 302.4 0.0 2.0 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KEZ46203.1 - 1.1e-26 93.7 0.0 2.8e-22 79.5 0.0 3.4 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region MFS_1 PF07690.16 KEZ46204.1 - 7e-40 137.0 38.5 7e-40 137.0 38.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ46204.1 - 7.8e-12 44.8 8.6 7.8e-12 44.8 8.6 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KEZ46204.1 - 1.7e-05 23.5 2.1 3.3e-05 22.5 2.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1072 PF06380.11 KEZ46204.1 - 0.8 9.6 3.5 0.52 10.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Sugar_tr PF00083.24 KEZ46205.1 - 9.6e-106 354.3 19.5 1.4e-105 353.8 19.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ46205.1 - 2.7e-24 85.8 27.2 2.7e-24 85.8 27.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.19 KEZ46205.1 - 0.016 14.0 8.3 0.014 14.2 1.3 2.4 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF2938 PF11158.8 KEZ46205.1 - 4.4 6.8 12.0 0.031 13.8 1.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2938) Phage_holin_3_2 PF04550.12 KEZ46205.1 - 4.8 7.8 9.8 1.9 9.1 3.9 2.9 2 1 1 3 3 3 0 Phage holin family 2 AIP3 PF03915.13 KEZ46206.1 - 2.2e-155 517.8 4.0 2.2e-155 517.8 4.0 1.5 2 0 0 2 2 2 1 Actin interacting protein 3 Wtap PF17098.5 KEZ46206.1 - 0.00079 19.4 0.5 0.00079 19.4 0.5 2.2 3 0 0 3 3 3 1 WTAP/Mum2p family DUF1664 PF07889.12 KEZ46206.1 - 0.029 14.4 3.9 0.28 11.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 KEZ46206.1 - 0.14 10.7 2.1 0.22 10.1 0.3 2.0 2 0 0 2 2 2 0 AAA domain FliL PF03748.14 KEZ46206.1 - 0.33 11.6 3.3 0.77 10.4 0.1 3.2 4 1 0 4 4 4 0 Flagellar basal body-associated protein FliL DivIC PF04977.15 KEZ46206.1 - 0.53 10.1 12.6 0.23 11.3 0.5 3.4 3 1 1 4 4 4 0 Septum formation initiator MIP-T3_C PF17749.1 KEZ46206.1 - 0.77 9.7 5.1 0.31 11.0 0.7 2.5 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region ATG16 PF08614.11 KEZ46206.1 - 0.8 9.9 13.9 6.9 6.8 0.1 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 KEZ46206.1 - 1.4 9.4 7.9 2.1 8.8 0.2 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FAD_binding_3 PF01494.19 KEZ46207.1 - 6.6e-24 84.8 0.1 1.1e-23 84.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ46207.1 - 6.5e-06 26.0 0.0 0.00055 19.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ46207.1 - 0.00011 22.3 0.1 0.00039 20.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ46207.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEZ46207.1 - 0.0017 17.5 0.0 0.0037 16.4 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 KEZ46207.1 - 0.0022 18.5 0.1 0.0053 17.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KEZ46207.1 - 0.0056 17.2 0.0 0.017 15.6 0.0 1.8 2 0 0 2 2 1 1 XdhC Rossmann domain ApbA PF02558.16 KEZ46207.1 - 0.017 14.8 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KEZ46207.1 - 0.019 14.8 0.1 0.044 13.7 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KEZ46207.1 - 0.035 14.1 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 KEZ46207.1 - 0.038 13.2 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KEZ46207.1 - 0.046 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 KEZ46207.1 - 0.046 12.8 0.8 0.083 11.9 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KEZ46207.1 - 0.053 12.8 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KEZ46207.1 - 0.088 13.4 0.1 0.22 12.2 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 KEZ46207.1 - 0.11 12.3 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_7 PF13241.6 KEZ46207.1 - 0.17 12.4 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Cellulase PF00150.18 KEZ46208.1 - 3.6e-48 164.4 0.3 4.7e-48 164.0 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KEZ46208.1 - 6e-05 22.8 0.1 7.7e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Ribosomal_S19 PF00203.21 KEZ46209.1 - 5.4e-28 96.7 0.0 6.3e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 KEZ46210.1 - 3.9e-25 87.6 0.4 3.9e-25 87.6 0.4 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KEZ46210.1 - 0.091 13.3 0.4 0.18 12.3 0.4 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ER_lumen_recept PF00810.18 KEZ46211.1 - 1.2e-52 178.7 10.4 2e-52 177.9 10.4 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KEZ46211.1 - 0.04 13.7 0.4 0.04 13.7 0.4 3.6 4 1 1 5 5 5 0 PQ loop repeat COX7B PF05392.11 KEZ46211.1 - 0.092 12.4 0.2 0.22 11.2 0.1 1.7 1 1 1 2 2 2 0 Cytochrome C oxidase chain VIIB LicD PF04991.13 KEZ46212.1 - 2.2e-20 73.8 9.3 2.8e-15 57.1 4.3 4.0 2 2 1 3 3 3 2 LicD family CDC45 PF02724.14 KEZ46212.1 - 5.7e-05 21.6 28.6 6.8e-05 21.4 28.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Endostatin PF06482.11 KEZ46212.1 - 0.18 11.3 10.6 0.28 10.6 10.6 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SRP-alpha_N PF04086.13 KEZ46212.1 - 0.18 11.7 36.6 0.26 11.2 36.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BC10 PF06726.12 KEZ46213.1 - 5e-14 52.3 12.0 8.3e-14 51.6 12.0 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 PRRSV_Env PF02340.15 KEZ46213.1 - 0.13 11.6 2.4 0.2 11.0 2.4 1.3 1 0 0 1 1 1 0 PRRSV putative envelope protein Nup160 PF11715.8 KEZ46214.1 - 0.018 13.7 0.0 0.06 12.0 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 MukF_M PF17192.4 KEZ46214.1 - 0.081 12.7 3.6 0.19 11.5 3.6 1.6 1 0 0 1 1 1 0 MukF middle domain ING PF12998.7 KEZ46214.1 - 0.29 11.8 1.7 1.3 9.6 0.1 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DNA_pol3_delta2 PF13177.6 KEZ46215.1 - 3.9e-10 39.7 0.1 9.5e-10 38.5 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KEZ46215.1 - 5.5e-06 26.7 0.2 9.2e-05 22.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain Rep_fac_C PF08542.11 KEZ46215.1 - 6.7e-06 26.4 0.2 3.5e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 KEZ46215.1 - 6.8e-06 26.5 0.1 1.7e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ46215.1 - 0.00011 22.6 0.9 0.0025 18.2 0.6 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KEZ46215.1 - 0.0028 17.4 0.2 0.0089 15.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KEZ46215.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KEZ46215.1 - 0.025 14.4 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ABC_tran PF00005.27 KEZ46215.1 - 0.067 13.7 0.1 0.19 12.3 0.0 1.8 2 1 0 2 2 2 0 ABC transporter T4SS-DNA_transf PF02534.14 KEZ46215.1 - 0.086 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer AMP-binding PF00501.28 KEZ46216.1 - 4.9e-89 298.8 0.2 7.6e-89 298.2 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ46216.1 - 5.6e-24 84.9 8.3 9.6e-24 84.2 2.2 3.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KEZ46216.1 - 8.7e-18 64.0 0.1 8.7e-18 64.0 0.1 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Reprolysin_5 PF13688.6 KEZ46217.1 - 5.7e-59 199.6 5.9 5.7e-59 199.6 5.9 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KEZ46217.1 - 2.2e-50 171.3 3.4 6.2e-50 169.8 3.4 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KEZ46217.1 - 1.2e-44 152.4 2.7 2.4e-44 151.4 2.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KEZ46217.1 - 2.3e-16 60.3 32.5 2.3e-16 60.3 32.5 4.4 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KEZ46217.1 - 4e-13 50.0 0.1 4e-13 50.0 0.1 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KEZ46217.1 - 0.0069 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide DUF4953 PF16313.5 KEZ46217.1 - 0.22 10.7 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 Met-zincin SelP_N PF04592.14 KEZ46219.1 - 0.79 9.1 7.0 0.98 8.8 7.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_L16 PF00252.18 KEZ46221.1 - 3.5e-32 111.2 0.3 4.8e-32 110.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 KEZ46222.1 - 4.3e-55 186.2 0.1 5e-54 182.7 0.0 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KEZ46222.1 - 1.2e-14 54.4 0.0 3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KEZ46222.1 - 2.2e-10 41.1 0.0 6.8e-10 39.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KEZ46222.1 - 1.9e-07 31.2 0.0 5.4e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KEZ46222.1 - 1.8e-06 27.9 0.0 4.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KEZ46222.1 - 2.5e-05 24.6 0.0 8.2e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ46222.1 - 0.0016 19.0 0.0 0.0054 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KEZ46222.1 - 0.0016 18.9 1.3 0.0036 17.7 0.0 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.6 KEZ46222.1 - 0.0032 17.5 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KEZ46222.1 - 0.028 14.6 0.3 0.13 12.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KEZ46222.1 - 0.041 13.8 0.5 0.27 11.1 0.5 2.1 1 1 1 2 2 2 0 NTPase AAA_28 PF13521.6 KEZ46222.1 - 0.058 13.6 2.4 0.3 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 KEZ46222.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 KEZ46222.1 - 0.16 11.8 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Vps8 PF12816.7 KEZ46222.1 - 0.2 11.1 0.1 0.84 9.1 0.1 1.9 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 GrpE PF01025.19 KEZ46224.1 - 1.9e-44 151.3 5.2 2.6e-44 150.8 5.2 1.2 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.12 KEZ46224.1 - 0.011 15.3 2.4 0.015 14.9 2.4 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4238 PF14022.6 KEZ46224.1 - 0.1 12.1 0.2 0.12 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Mito_carr PF00153.27 KEZ46225.1 - 5e-54 180.2 1.1 1.4e-19 69.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chorismate_synt PF01264.21 KEZ46226.1 - 1e-137 458.2 0.0 1.2e-137 458.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 KEZ46227.1 - 5.3e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.25 KEZ46228.1 - 6.7e-50 169.9 0.1 2.2e-33 115.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46228.1 - 7e-22 77.9 0.8 2.9e-20 72.6 0.2 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ46228.1 - 0.00013 21.4 0.0 0.00032 20.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ46228.1 - 0.0047 16.9 0.1 0.0047 16.9 0.1 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Glycos_transf_1 PF00534.20 KEZ46229.1 - 1.9e-35 121.9 0.0 6.2e-34 117.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KEZ46229.1 - 4.8e-17 62.6 0.1 1.8e-16 60.8 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KEZ46229.1 - 1.1e-13 51.6 0.2 2.2e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KEZ46229.1 - 1e-07 32.6 0.4 1e-07 32.6 0.4 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KEZ46229.1 - 5.2e-06 26.8 0.0 1.5e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 ALG11_N PF15924.5 KEZ46229.1 - 4.1e-05 23.7 1.6 0.038 14.1 0.2 2.9 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus AAA_16 PF13191.6 KEZ46230.1 - 0.0016 18.9 0.3 0.0058 17.0 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KEZ46230.1 - 0.0022 17.9 0.0 0.007 16.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 KEZ46230.1 - 0.0028 17.9 0.0 0.0096 16.2 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 KEZ46230.1 - 0.031 14.9 0.7 0.16 12.5 0.1 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family IPK PF03770.16 KEZ46232.1 - 3.4e-55 187.0 0.0 1e-54 185.4 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase DAO PF01266.24 KEZ46233.1 - 8.4e-29 101.2 0.2 9.8e-29 101.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase CN_hydrolase PF00795.22 KEZ46234.1 - 1.6e-28 99.7 0.1 5.3e-22 78.4 0.1 2.7 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase Nitroreductase PF00881.24 KEZ46234.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Nitroreductase family HATPase_c_3 PF13589.6 KEZ46235.1 - 7.3e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KEZ46235.1 - 1.2e-08 34.9 0.0 3.8e-07 30.0 0.0 2.6 3 0 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KEZ46235.1 - 0.00017 22.1 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TcpA PF05946.12 KEZ46235.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Fungal_trans_2 PF11951.8 KEZ46236.1 - 1.9e-48 165.2 0.0 2.9e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46236.1 - 1.1e-06 28.6 14.1 1.9e-06 27.8 14.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.12 KEZ46238.1 - 2.5e-89 300.1 49.5 2.5e-89 300.1 49.5 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 KEZ46238.1 - 5.6e-22 77.8 1.6 8.8e-22 77.2 0.1 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Tetraspanin PF00335.20 KEZ46239.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.7 1 1 0 1 1 1 1 Tetraspanin family FtsX PF02687.21 KEZ46239.1 - 3.4 8.2 0.0 3.4 8.2 0.0 2.9 2 1 0 2 2 2 0 FtsX-like permease family SNO PF01174.19 KEZ46240.1 - 1.8e-54 184.5 0.0 2.9e-53 180.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KEZ46240.1 - 9.3e-08 31.9 0.0 2.2e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KEZ46240.1 - 0.00036 20.3 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KEZ46240.1 - 0.00044 20.1 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 KEZ46240.1 - 0.0032 17.2 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 ParD PF09386.10 KEZ46240.1 - 0.13 12.6 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Antitoxin ParD HMGL-like PF00682.19 KEZ46241.1 - 9.9e-44 149.9 0.1 4e-42 144.6 0.1 2.0 1 1 0 1 1 1 1 HMGL-like MCR_C PF04609.12 KEZ46241.1 - 0.06 12.4 0.1 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C ComA PF02679.15 KEZ46241.1 - 0.073 12.5 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF362 PF04015.12 KEZ46241.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF362) ATP-synt_ab PF00006.25 KEZ46242.1 - 9.8e-68 228.0 0.0 1.4e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KEZ46242.1 - 1.8e-11 44.4 0.7 3.3e-11 43.6 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 KEZ46242.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) bZIP_1 PF00170.21 KEZ46243.1 - 1.4e-09 37.9 10.4 3.4e-09 36.7 10.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KEZ46243.1 - 0.0031 17.5 12.5 0.0031 17.5 12.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper MFS_1 PF07690.16 KEZ46244.1 - 2.7e-28 98.9 67.0 9.8e-15 54.3 38.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM176 PF14851.6 KEZ46244.1 - 0.18 11.5 0.2 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 FAM176 family IncF PF17626.2 KEZ46244.1 - 1.8 8.9 10.1 0.23 11.9 2.9 3.0 2 1 1 3 3 3 0 Inclusion membrane protein F AAA PF00004.29 KEZ46245.1 - 7.5e-18 65.2 0.0 1.9e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KEZ46245.1 - 0.0014 18.9 0.2 0.018 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ46245.1 - 0.0017 18.8 0.0 0.007 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 KEZ46245.1 - 0.05 14.0 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KEZ46245.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.6 KEZ46246.1 - 3.7e-15 56.0 0.0 4.7e-08 33.2 0.0 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ46246.1 - 1.5e-14 53.8 0.0 2.3e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 KEZ46246.1 - 7e-12 44.6 0.0 0.00086 19.0 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ46246.1 - 3.7e-08 32.9 0.0 0.027 14.6 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46246.1 - 3.6e-07 29.9 0.2 0.0026 17.8 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ46246.1 - 6.7e-07 29.0 0.0 0.025 14.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 KEZ46246.1 - 2.4e-06 28.0 0.0 9.4e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.6 KEZ46246.1 - 5.9e-06 26.0 0.0 0.18 11.9 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ46246.1 - 4e-05 23.1 0.4 0.28 10.5 0.0 2.8 2 1 1 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 KEZ46246.1 - 0.00036 21.1 0.0 3.5 8.7 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46246.1 - 0.00074 20.0 0.0 2.9 8.5 0.0 3.5 3 1 0 3 3 2 2 Tetratricopeptide repeat AAA_33 PF13671.6 KEZ46246.1 - 0.0042 17.2 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ46246.1 - 0.007 16.8 0.0 0.023 15.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KEZ46246.1 - 0.0089 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 KaiC NACHT PF05729.12 KEZ46246.1 - 0.013 15.4 0.0 0.043 13.7 0.0 2.0 1 1 0 1 1 1 0 NACHT domain DnaB_C PF03796.15 KEZ46246.1 - 0.034 13.5 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 KEZ46246.1 - 0.047 13.7 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ46246.1 - 0.048 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.6 KEZ46246.1 - 0.068 13.8 0.0 10 6.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 KEZ46246.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TB2_DP1_HVA22 PF03134.19 KEZ46247.1 - 0.019 14.9 0.2 0.044 13.7 0.2 1.5 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Amidase PF01425.21 KEZ46248.1 - 1.9e-22 79.9 0.1 3e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Amidase DUF2749 PF10907.8 KEZ46249.1 - 0.042 14.0 1.9 0.28 11.4 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) APH PF01636.23 KEZ46250.1 - 4.1e-20 72.7 0.0 1.3e-19 71.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEZ46250.1 - 0.0011 18.6 0.1 0.4 10.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 KEZ46250.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAD_binding_8 PF13450.6 KEZ46251.1 - 1.2e-11 44.7 0.3 2.3e-11 43.8 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ46251.1 - 3.7e-08 32.9 2.8 5.9e-08 32.2 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KEZ46251.1 - 4.6e-08 32.8 0.3 8.9e-08 31.9 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KEZ46251.1 - 8.8e-07 28.8 0.5 2.1e-06 27.6 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KEZ46251.1 - 1.3e-05 24.7 0.1 0.00052 19.4 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KEZ46251.1 - 1.7e-05 23.7 0.8 3e-05 22.9 0.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KEZ46251.1 - 3.8e-05 23.1 0.1 0.0002 20.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KEZ46251.1 - 0.00017 22.1 1.3 0.00061 20.3 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ46251.1 - 0.00039 19.8 1.0 0.00068 19.0 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KEZ46251.1 - 0.0014 17.9 0.9 0.0039 16.5 0.3 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KEZ46251.1 - 0.0053 16.0 0.0 0.0089 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ46251.1 - 0.0078 15.4 0.2 3.7 6.6 0.3 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KEZ46251.1 - 0.12 11.5 2.6 0.22 10.6 2.7 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A Cpn60_TCP1 PF00118.24 KEZ46251.1 - 0.14 10.7 0.2 0.21 10.2 0.2 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family FAD_binding_3 PF01494.19 KEZ46252.1 - 3.6e-16 59.3 0.1 1.3e-15 57.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ46252.1 - 5.4e-06 26.2 0.1 9.5e-05 22.1 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ46252.1 - 0.00016 21.9 0.1 0.00049 20.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEZ46252.1 - 0.00074 19.5 0.0 0.69 9.9 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KEZ46252.1 - 0.015 14.6 0.1 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KEZ46252.1 - 0.047 12.8 0.0 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.24 KEZ46252.1 - 0.048 12.8 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 KEZ46252.1 - 0.049 12.9 0.0 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KEZ46252.1 - 0.087 12.1 0.1 0.59 9.3 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hist_deacetyl PF00850.19 KEZ46252.1 - 0.12 11.9 0.0 0.66 9.4 0.0 2.0 1 1 0 1 1 1 0 Histone deacetylase domain Gcd10p PF04189.13 KEZ46253.1 - 4.6e-110 367.4 0.0 6.2e-110 367.0 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family SAPS PF04499.15 KEZ46253.1 - 0.11 11.3 0.8 0.16 10.7 0.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein P21-Arc PF04062.14 KEZ46254.1 - 3.5e-71 238.8 0.0 4e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit AAA PF00004.29 KEZ46255.1 - 9.6e-16 58.4 0.0 1.7e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KEZ46255.1 - 1.4e-13 51.0 0.0 3.9e-13 49.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KEZ46255.1 - 7.2e-12 45.4 0.0 1.3e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KEZ46255.1 - 1.9e-08 34.5 0.0 4.1e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KEZ46255.1 - 8.9e-07 29.2 0.0 2.9e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 KEZ46255.1 - 4.8e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KEZ46255.1 - 8.7e-06 26.2 0.1 0.00012 22.5 0.0 2.5 2 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KEZ46255.1 - 2.2e-05 24.7 0.0 0.00018 21.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ46255.1 - 2.5e-05 24.2 0.1 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KEZ46255.1 - 4.6e-05 23.2 0.1 0.00014 21.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KEZ46255.1 - 5.7e-05 23.0 0.1 0.00012 21.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.13 KEZ46255.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KEZ46255.1 - 0.00019 21.3 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KEZ46255.1 - 0.0002 21.1 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KEZ46255.1 - 0.00021 21.3 0.3 0.0022 18.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KEZ46255.1 - 0.00025 21.4 0.4 0.00061 20.2 0.1 1.9 2 1 0 2 2 1 1 AAA domain AAA_3 PF07726.11 KEZ46255.1 - 0.00046 20.0 0.2 0.0037 17.1 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KEZ46255.1 - 0.0008 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KEZ46255.1 - 0.0019 17.7 0.1 0.64 9.4 0.0 2.4 1 1 1 2 2 2 1 PhoH-like protein AAA_18 PF13238.6 KEZ46255.1 - 0.0023 18.5 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 KEZ46255.1 - 0.0029 17.0 0.0 0.037 13.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 KEZ46255.1 - 0.0083 15.5 0.1 0.054 12.9 0.1 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KEZ46255.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KEZ46255.1 - 0.016 14.8 0.0 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ46255.1 - 0.017 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 KEZ46255.1 - 0.024 14.7 0.0 0.14 12.2 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KEZ46255.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KEZ46255.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KEZ46255.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MCM PF00493.23 KEZ46255.1 - 0.13 11.4 0.1 1.3 8.0 0.1 2.4 1 1 0 1 1 1 0 MCM P-loop domain IstB_IS21 PF01695.17 KEZ46255.1 - 0.16 11.7 0.0 0.41 10.3 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Fringe PF02434.16 KEZ46256.1 - 1.2e-06 28.2 2.8 3.1e-05 23.5 1.0 2.9 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 KEZ46256.1 - 0.0022 17.9 1.1 0.0057 16.5 1.1 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 KEZ46256.1 - 0.026 14.3 0.6 0.067 13.0 0.6 1.6 1 0 0 1 1 1 0 PAN-like domain Galactosyl_T PF01762.21 KEZ46256.1 - 0.13 12.0 0.5 0.82 9.5 0.2 1.9 1 1 1 2 2 2 0 Galactosyltransferase Asp PF00026.23 KEZ46257.1 - 3.5e-53 181.1 0.8 4.7e-53 180.7 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ46257.1 - 1.5e-07 31.8 0.3 8e-06 26.2 0.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KEZ46257.1 - 0.0041 17.7 0.0 0.15 12.8 0.0 2.8 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.6 KEZ46257.1 - 0.0059 16.4 0.1 0.83 9.4 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KEZ46257.1 - 0.043 14.4 0.0 1.7 9.2 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease 2OG-FeII_Oxy_3 PF13640.6 KEZ46258.1 - 1.8e-09 38.3 0.1 2.9e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-U PF06728.13 KEZ46258.1 - 0.24 10.4 0.0 0.31 10.0 0.0 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U BAGE PF08180.11 KEZ46258.1 - 0.39 10.8 1.1 0.84 9.8 1.1 1.6 1 0 0 1 1 1 0 B melanoma antigen family Thioredoxin_6 PF13848.6 KEZ46259.1 - 1.2e-11 44.8 0.0 1.9e-10 41.0 0.0 2.4 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 KEZ46259.1 - 1.9e-09 37.4 0.0 1.1e-07 31.7 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Pro-kuma_activ PF09286.11 KEZ46260.1 - 2.4e-35 121.9 0.0 4.5e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Glyco_transf_25 PF01755.17 KEZ46260.1 - 2e-09 37.6 0.0 9e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Peptidase_S8 PF00082.22 KEZ46260.1 - 2.1e-05 23.9 0.0 3.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.6 KEZ46261.1 - 2.2e-12 47.2 1.2 2.1e-09 37.7 0.0 4.3 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 KEZ46261.1 - 1.7e-11 44.1 0.1 0.00035 20.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 KEZ46261.1 - 7.3e-11 42.5 1.0 1.6e-09 38.2 0.1 3.2 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ46261.1 - 8.2e-09 35.6 6.9 1.3e-08 34.9 0.5 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ46261.1 - 2e-08 33.8 0.3 0.00099 19.4 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat DUF1442 PF07279.11 KEZ46261.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) CDH-cyt PF16010.5 KEZ46262.1 - 5.1e-48 163.2 0.3 6.5e-48 162.8 0.3 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase RdRP PF05183.12 KEZ46263.1 - 2e-184 614.5 0.0 2.5e-184 614.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase BUD22 PF09073.10 KEZ46264.1 - 0.016 14.6 8.1 0.021 14.2 8.1 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 KEZ46264.1 - 0.045 12.1 1.5 0.056 11.7 1.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KEZ46264.1 - 0.083 12.3 6.7 0.15 11.5 6.7 1.3 1 1 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEZ46264.1 - 0.3 9.2 6.1 0.38 8.9 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 KEZ46264.1 - 1.2 8.0 5.3 1.6 7.6 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) YL1 PF05764.13 KEZ46264.1 - 2.8 8.0 5.7 4.4 7.4 5.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Histone PF00125.24 KEZ46265.1 - 1.9e-18 67.1 0.0 2.5e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KEZ46265.1 - 3.8e-13 48.9 0.1 9.8e-13 47.6 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KEZ46265.1 - 2.6e-05 24.4 0.0 4.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 KEZ46266.1 - 5.9e-11 42.2 0.3 1.2e-10 41.2 0.3 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KEZ46266.1 - 2.2e-05 24.2 0.0 5.1e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mre11_DNA_bind PF04152.14 KEZ46267.1 - 8.7e-53 179.1 0.6 2.7e-52 177.5 0.1 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KEZ46267.1 - 3.9e-15 56.9 2.6 7.6e-15 56.0 2.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_binding_1 PF01035.20 KEZ46268.1 - 1.3e-09 38.0 0.3 7.8e-09 35.5 0.3 2.0 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain His_Phos_1 PF00300.22 KEZ46268.1 - 6.7e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cwf_Cwc_15 PF04889.12 KEZ46268.1 - 0.00086 19.1 10.0 0.0012 18.7 10.0 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KEZ46268.1 - 0.0021 18.4 14.8 0.0044 17.4 14.8 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nop14 PF04147.12 KEZ46268.1 - 0.084 11.1 7.0 0.093 10.9 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KEZ46268.1 - 0.099 12.5 5.0 0.15 11.9 5.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 KEZ46268.1 - 0.12 11.5 20.8 0.17 11.0 20.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SpoIIIAH PF12685.7 KEZ46268.1 - 0.12 12.2 4.7 0.17 11.7 4.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.13 KEZ46268.1 - 0.12 12.3 6.9 0.18 11.8 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 KEZ46268.1 - 0.21 11.0 7.7 0.26 10.7 7.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KEZ46268.1 - 0.24 10.7 7.9 0.29 10.4 7.9 1.1 1 0 0 1 1 1 0 BUD22 Nucleo_P87 PF07267.11 KEZ46268.1 - 0.36 9.6 3.7 0.51 9.1 3.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 KEZ46268.1 - 0.37 9.0 7.2 0.5 8.6 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 KEZ46268.1 - 0.43 10.1 7.5 0.66 9.5 7.5 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KEZ46268.1 - 0.67 9.2 16.8 0.97 8.7 16.8 1.2 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 KEZ46268.1 - 0.69 9.5 11.1 1.1 8.8 11.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2722 PF10846.8 KEZ46268.1 - 0.73 8.7 5.7 0.96 8.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FAM176 PF14851.6 KEZ46268.1 - 2 8.0 8.2 3.3 7.3 8.2 1.3 1 0 0 1 1 1 0 FAM176 family FYDLN_acid PF09538.10 KEZ46268.1 - 2.1 9.1 16.3 4 8.2 16.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Sporozoite_P67 PF05642.11 KEZ46268.1 - 2.3 6.2 8.1 3.2 5.7 8.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 KEZ46268.1 - 2.3 8.2 11.1 4.1 7.4 11.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2076 PF09849.9 KEZ46268.1 - 2.8 7.9 8.9 4.3 7.3 8.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pox_Ag35 PF03286.14 KEZ46268.1 - 3.5 7.4 9.3 6.4 6.5 9.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Herpes_LMP1 PF05297.11 KEZ46268.1 - 3.7 6.6 5.7 5.2 6.2 5.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DNA_pol_phi PF04931.13 KEZ46268.1 - 4.1 5.4 18.4 5.4 5.0 18.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 KEZ46268.1 - 4.9 7.6 14.5 9.3 6.7 14.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinesin PF00225.23 KEZ46269.1 - 2.2e-90 303.0 0.0 2.2e-90 303.0 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ46269.1 - 1.9e-17 63.6 0.0 3.7e-14 52.9 0.0 3.3 3 0 0 3 3 3 2 Microtubule binding HisKA PF00512.25 KEZ46269.1 - 2 8.5 11.6 2.8 8.1 2.5 5.1 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain NACHT PF05729.12 KEZ46270.1 - 9.2e-10 38.7 0.0 2.6e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.6 KEZ46270.1 - 0.001 19.6 0.3 0.089 13.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KEZ46270.1 - 0.03 14.1 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KEZ46270.1 - 0.051 14.0 0.1 0.36 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KEZ46270.1 - 0.056 13.8 1.5 1.4 9.3 0.0 3.5 3 2 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 KEZ46270.1 - 0.13 12.8 0.0 0.53 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KEZ46270.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TSC22 PF01166.18 KEZ46270.1 - 0.15 12.4 0.2 0.54 10.6 0.2 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family ABC_tran PF00005.27 KEZ46270.1 - 0.19 12.2 0.2 0.65 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter BRO1 PF03097.18 KEZ46271.1 - 5e-118 394.3 0.0 6.9e-118 393.8 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KEZ46271.1 - 3.9e-81 272.6 3.4 8.6e-81 271.5 0.9 2.3 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Ysc84 PF04366.12 KEZ46272.1 - 2.1e-46 156.8 0.0 3.6e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Band_7 PF01145.25 KEZ46273.1 - 1e-17 64.7 0.1 1e-17 64.7 0.1 3.3 2 1 0 3 3 3 1 SPFH domain / Band 7 family PHC2_SAM_assoc PF16616.5 KEZ46273.1 - 1.4 9.8 5.9 0.74 10.6 2.3 2.2 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 LCIB_C_CA PF18599.1 KEZ46273.1 - 4.4 6.5 7.6 3.7 6.8 5.6 1.8 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases FTA2 PF13095.6 KEZ46274.1 - 1.4e-05 24.8 0.0 0.0013 18.4 0.0 2.6 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Isochorismatase PF00857.20 KEZ46278.1 - 1.1e-40 139.6 0.1 1.2e-40 139.5 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF87 PF01935.17 KEZ46278.1 - 0.15 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Abhydrolase_1 PF00561.20 KEZ46279.1 - 5.4e-19 68.8 0.1 4e-17 62.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ46279.1 - 2.2e-15 57.8 0.4 2.8e-15 57.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KEZ46279.1 - 1.8e-12 47.1 0.0 3.7e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KEZ46279.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KEZ46279.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.18 KEZ46279.1 - 0.06 12.9 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family EHN PF06441.12 KEZ46279.1 - 0.12 12.7 0.0 0.94 9.9 0.0 2.2 2 0 0 2 2 2 0 Epoxide hydrolase N terminus MFS_1 PF07690.16 KEZ46280.1 - 7e-17 61.4 31.4 7e-17 61.4 31.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_28 PF00295.17 KEZ46282.1 - 2.5e-41 141.8 8.5 4.4e-41 141.0 8.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Peptidase_M14 PF00246.24 KEZ46283.1 - 4e-83 279.5 0.1 5.2e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_16 PF00722.21 KEZ46283.1 - 2.8e-13 49.7 0.1 6.4e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Propep_M14 PF02244.16 KEZ46283.1 - 0.09 13.2 0.2 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide DUF1996 PF09362.10 KEZ46284.1 - 6e-83 278.4 1.3 7.1e-83 278.2 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) p450 PF00067.22 KEZ46285.1 - 3.3e-67 227.2 0.1 4.6e-66 223.4 0.0 1.9 1 1 1 2 2 2 2 Cytochrome P450 DUF3500 PF12006.8 KEZ46286.1 - 1.6e-106 356.1 0.0 1.9e-106 355.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Methyltransf_2 PF00891.18 KEZ46288.1 - 6e-21 74.7 0.0 8.7e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KEZ46288.1 - 0.00051 20.0 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain Fungal_trans PF04082.18 KEZ46289.1 - 1.1e-14 54.1 0.4 1.8e-14 53.4 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cons_hypoth698 PF03601.14 KEZ46289.1 - 0.079 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MFS_1 PF07690.16 KEZ46290.1 - 1.2e-31 109.9 24.6 7.2e-28 97.5 20.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ46290.1 - 1.2e-11 44.1 15.5 1.9e-11 43.5 15.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4006 PF13179.6 KEZ46290.1 - 0.14 12.1 0.1 0.7 9.8 0.1 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF3671 PF12420.8 KEZ46290.1 - 3.8 7.6 5.7 12 6.0 0.0 3.8 4 2 0 4 4 4 0 Protein of unknown function MFS_1 PF07690.16 KEZ46291.1 - 2.5e-09 36.5 5.5 0.0011 18.0 1.4 3.2 2 2 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KEZ46291.1 - 4.7e-05 22.1 0.0 8e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein ADC PF06314.11 KEZ46292.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Acetyltransf_1 PF00583.25 KEZ46293.1 - 1.9e-14 53.9 0.0 2.3e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KEZ46293.1 - 4.4e-08 33.4 0.1 7.7e-08 32.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KEZ46293.1 - 6.9e-07 29.2 0.0 3.1e-06 27.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KEZ46293.1 - 9.6e-07 28.8 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KEZ46293.1 - 7.3e-05 22.8 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KEZ46293.1 - 0.00098 19.8 0.0 0.0013 19.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KEZ46293.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KEZ46293.1 - 0.01 16.0 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 KEZ46293.1 - 0.047 13.1 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 KEZ46293.1 - 0.1 12.6 0.0 0.91 9.6 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase NmrA PF05368.13 KEZ46294.1 - 5.5e-42 143.9 0.0 7.1e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ46294.1 - 1.6e-17 64.0 0.0 2.1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KEZ46294.1 - 5e-08 32.3 0.0 7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KEZ46294.1 - 3.4e-07 30.0 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ46294.1 - 0.0002 21.3 0.1 0.00032 20.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KEZ46294.1 - 0.0008 18.6 0.0 0.0059 15.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KEZ46294.1 - 0.0031 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KEZ46294.1 - 0.0041 16.3 0.0 0.009 15.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KEZ46294.1 - 0.026 14.0 0.0 0.085 12.3 0.0 1.7 1 1 1 2 2 2 0 short chain dehydrogenase DapB_N PF01113.20 KEZ46294.1 - 0.049 13.7 0.0 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KEZ46294.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.8 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 KEZ46295.1 - 6.4e-89 298.8 0.0 7.4e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhoQ_Sensor PF08918.10 KEZ46295.1 - 0.058 13.2 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor FMO-like PF00743.19 KEZ46296.1 - 2.1e-13 49.6 0.0 5.3e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ46296.1 - 1.5e-08 34.8 0.0 3.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KEZ46296.1 - 1.6e-06 27.6 0.0 0.00023 20.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ46296.1 - 4.3e-05 22.9 0.0 0.0012 18.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ46296.1 - 0.00012 21.4 0.0 0.074 12.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ46296.1 - 0.0058 16.6 0.0 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Holin_SPP1 PF04688.13 KEZ46297.1 - 0.085 13.0 0.6 0.26 11.5 0.2 2.0 2 0 0 2 2 2 0 SPP1 phage holin FAD_binding_3 PF01494.19 KEZ46298.1 - 1.7e-89 300.5 0.0 2.4e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KEZ46298.1 - 9.5e-59 198.1 0.0 1.8e-58 197.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KEZ46298.1 - 2.1e-05 23.4 0.3 3.1e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KEZ46298.1 - 5.6e-05 22.4 0.3 9.1e-05 21.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ46298.1 - 0.00078 18.8 0.4 0.002 17.4 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ46298.1 - 0.0013 18.9 0.1 0.013 15.7 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KEZ46298.1 - 0.0015 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KEZ46298.1 - 0.0017 17.7 0.3 0.0027 17.0 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ46298.1 - 0.0095 15.0 0.3 0.017 14.2 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ46298.1 - 0.02 14.2 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEZ46298.1 - 0.03 13.6 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KEZ46298.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ46298.1 - 0.16 11.0 0.3 0.32 10.0 0.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KEZ46298.1 - 0.22 10.3 0.5 0.64 8.8 0.2 1.9 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.25 KEZ46299.1 - 2.9e-19 69.3 0.1 2.5e-17 63.0 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ46299.1 - 6.5e-11 42.2 0.4 6.1e-10 39.1 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ46299.1 - 0.00011 22.2 0.1 0.00016 21.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KEZ46299.1 - 0.011 16.0 0.3 0.018 15.3 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CoA_binding PF02629.19 KEZ46300.1 - 8.9e-22 77.6 0.6 8.9e-22 77.6 0.6 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KEZ46300.1 - 7.1e-18 64.9 0.1 1.2e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KEZ46300.1 - 6.4e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 KEZ46301.1 - 4.9e-65 218.9 0.0 6.9e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KEZ46301.1 - 3.4e-18 65.9 0.4 6.1e-18 65.1 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KEZ46301.1 - 5.8e-12 45.5 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KEZ46301.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain Citrate_bind PF16114.5 KEZ46301.1 - 0.023 14.2 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding CPSase_L_D2 PF02786.17 KEZ46301.1 - 0.025 14.1 0.6 0.064 12.7 0.1 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain adh_short_C2 PF13561.6 KEZ46302.1 - 1.9e-34 119.2 0.0 2.4e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ46302.1 - 1.4e-16 60.5 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Amidase PF01425.21 KEZ46303.1 - 8.6e-14 51.3 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Amidase FAD_binding_4 PF01565.23 KEZ46304.1 - 5.6e-30 103.9 0.1 8.2e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ46304.1 - 0.00022 20.9 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain MADF_DNA_bdg PF10545.9 KEZ46305.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_1 PF07690.16 KEZ46306.1 - 2.2e-35 122.3 21.5 2.2e-35 122.3 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ46306.1 - 6.8e-12 45.0 11.5 6.8e-12 45.0 11.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter RPE65 PF03055.15 KEZ46307.1 - 7.4e-105 351.8 0.0 8.4e-105 351.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Cupin_2 PF07883.11 KEZ46308.1 - 1.2e-21 76.2 0.9 4.5e-14 51.9 0.5 2.8 3 0 0 3 3 3 2 Cupin domain AraC_binding PF02311.19 KEZ46308.1 - 0.00076 19.4 1.1 1.4 8.8 0.3 2.6 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_3 PF05899.12 KEZ46308.1 - 0.0026 17.4 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 KEZ46308.1 - 0.0029 17.8 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_1 PF00190.22 KEZ46308.1 - 0.035 13.7 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Cupin DUF4859 PF16151.5 KEZ46308.1 - 0.035 14.0 0.0 0.38 10.6 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4859) FAD_binding_3 PF01494.19 KEZ46309.1 - 8.8e-18 64.7 0.0 2.1e-17 63.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KEZ46309.1 - 1.4e-12 47.9 5.6 3.6e-06 26.8 3.7 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KEZ46309.1 - 5.8e-10 38.9 0.5 6.2e-05 22.4 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ46309.1 - 6.5e-09 35.9 0.6 2.4e-08 34.1 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ46309.1 - 3.6e-07 30.7 0.1 0.00034 21.1 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KEZ46309.1 - 8.2e-07 28.2 3.0 0.078 11.8 0.0 3.1 2 1 1 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 KEZ46309.1 - 2.6e-06 26.4 0.6 0.0032 16.3 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KEZ46309.1 - 3.1e-06 26.6 2.7 5.4e-06 25.8 2.7 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KEZ46309.1 - 8.1e-05 22.1 1.5 0.049 12.9 0.6 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KEZ46309.1 - 0.00033 19.8 2.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 KEZ46309.1 - 0.00047 19.3 1.8 0.0081 15.3 1.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KEZ46309.1 - 0.00062 19.2 5.5 0.0012 18.2 5.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KEZ46309.1 - 0.00083 18.7 1.2 0.19 10.9 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ46309.1 - 0.0042 17.1 1.6 0.067 13.2 1.6 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KEZ46309.1 - 0.02 14.4 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KEZ46309.1 - 0.035 13.4 0.8 0.098 11.9 0.3 1.9 2 0 0 2 2 2 0 Thi4 family SE PF08491.10 KEZ46309.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 KEZ46309.1 - 0.14 11.4 0.3 0.28 10.4 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KEZ46309.1 - 0.18 11.7 1.0 0.29 11.0 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAA_hydrolase PF01557.18 KEZ46310.1 - 8.2e-53 179.3 0.0 1.2e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ADH_zinc_N PF00107.26 KEZ46311.1 - 2.4e-32 111.6 0.6 3.8e-32 111.0 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ46311.1 - 2.7e-14 54.4 0.0 4.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ46311.1 - 2.2e-05 24.3 0.0 0.00027 20.8 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 KEZ46311.1 - 0.0017 17.9 0.3 0.0025 17.3 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 KEZ46311.1 - 0.019 15.2 0.2 0.041 14.1 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KEZ46311.1 - 0.037 13.3 0.8 0.069 12.4 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HupF_HypC PF01455.18 KEZ46311.1 - 0.068 13.3 0.2 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 HupF/HypC family ADH_N_2 PF16884.5 KEZ46311.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF676 PF05057.14 KEZ46312.1 - 0.0025 17.3 0.0 0.055 13.0 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF4032 PF13224.6 KEZ46312.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) DUF4570 PF15134.6 KEZ46312.1 - 0.12 12.4 0.2 22 5.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) NAD_binding_10 PF13460.6 KEZ46313.1 - 4.1e-11 43.1 0.0 7.1e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DUF4246 PF14033.6 KEZ46316.1 - 2.1e-42 145.8 0.0 8.2e-28 97.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4246) p450 PF00067.22 KEZ46316.1 - 1.4e-30 106.5 0.0 1.9e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 KEZ46316.1 - 0.0047 17.1 0.1 0.012 15.8 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Alpha_GJ PF03229.13 KEZ46317.1 - 0.34 11.5 8.5 0.11 13.0 5.4 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J MFS_1 PF07690.16 KEZ46318.1 - 1.5e-36 126.0 28.9 1.5e-36 126.0 28.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ABM PF03992.16 KEZ46320.1 - 3.2e-07 30.3 1.2 0.0026 17.8 0.8 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Cyclase PF04199.13 KEZ46321.1 - 3e-14 53.4 0.1 6.5e-14 52.3 0.1 1.5 1 1 1 2 2 2 1 Putative cyclase DUF995 PF06191.12 KEZ46321.1 - 0.092 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF995) Fungal_trans PF04082.18 KEZ46322.1 - 5.1e-13 48.7 0.0 8.8e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46322.1 - 2e-07 31.0 8.8 3.7e-07 30.2 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 KEZ46323.1 - 1.9e-17 62.9 0.5 2.2e-14 52.8 0.1 2.7 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KEZ46323.1 - 4.5e-06 26.1 0.1 0.00019 20.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KEZ46323.1 - 6.1e-06 25.7 0.0 0.00014 21.2 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KEZ46323.1 - 2.4e-05 23.7 0.0 0.00095 18.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ46323.1 - 5.3e-05 23.0 0.1 0.1 12.1 0.1 3.2 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ46323.1 - 0.0002 21.5 0.0 0.00076 19.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KEZ46323.1 - 0.0076 16.2 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEZ46323.1 - 0.013 16.0 0.0 0.6 10.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KEZ46323.1 - 0.074 12.3 0.0 8.7 5.5 0.0 2.6 2 0 0 2 2 2 0 Thi4 family DUF4899 PF16240.5 KEZ46323.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) Clr5 PF14420.6 KEZ46324.1 - 0.00013 22.1 2.8 0.0003 20.9 2.8 1.7 1 0 0 1 1 1 1 Clr5 domain Egh16-like PF11327.8 KEZ46325.1 - 1.7e-21 77.5 3.8 3.8e-21 76.3 3.8 1.5 1 0 0 1 1 1 1 Egh16-like virulence factor Egh16-like PF11327.8 KEZ46326.1 - 1.8e-39 136.1 4.2 2.1e-39 135.8 4.2 1.0 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 KEZ46326.1 - 0.028 14.5 0.5 0.043 13.9 0.1 1.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain Izumo-Ig PF16706.5 KEZ46326.1 - 0.039 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Ig_3 PF13927.6 KEZ46326.1 - 0.041 14.5 0.2 0.19 12.4 0.1 2.0 1 1 1 2 2 2 0 Immunoglobulin domain Dynamin_N PF00350.23 KEZ46327.1 - 4.3e-08 33.4 0.0 1.3e-07 31.9 0.0 1.9 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KEZ46327.1 - 1.1e-06 28.7 0.0 0.0022 18.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KEZ46327.1 - 8e-05 22.6 0.0 0.0006 19.7 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KEZ46327.1 - 0.001 19.5 0.1 0.0097 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KEZ46327.1 - 0.0024 18.1 0.1 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KEZ46327.1 - 0.017 15.6 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.16 KEZ46327.1 - 0.1 11.9 0.1 0.25 10.7 0.1 1.7 1 0 0 1 1 1 0 AIG1 family EHN PF06441.12 KEZ46328.1 - 2.6e-30 105.0 0.0 4e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KEZ46328.1 - 5.6e-12 45.8 0.0 7.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KEZ46328.1 - 5.5e-06 27.1 0.1 7.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 KEZ46329.1 - 7.2e-44 148.3 0.1 5.4e-11 42.9 0.1 6.4 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KEZ46329.1 - 8.7e-34 111.7 7.2 0.00061 20.1 0.0 12.4 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.6 KEZ46329.1 - 2e-33 114.3 10.1 4.3e-08 33.5 0.1 8.8 4 1 7 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KEZ46329.1 - 5.2e-26 89.9 25.8 0.00028 21.2 0.0 11.2 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 KEZ46329.1 - 4.2e-20 71.5 10.4 0.00015 22.0 0.0 8.7 7 2 2 9 9 9 5 Ankyrin repeats (many copies) F-box-like PF12937.7 KEZ46329.1 - 0.00027 20.8 0.1 0.00054 19.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like VWA_3_C PF18571.1 KEZ46329.1 - 0.77 9.7 4.6 58 3.7 0.0 4.2 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Zn_clus PF00172.18 KEZ46330.1 - 1.2e-07 31.7 9.3 2e-07 31.0 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEZ46330.1 - 0.04 12.7 0.0 0.076 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain RTA1 PF04479.13 KEZ46331.1 - 1.5e-76 256.6 5.1 1.5e-76 256.6 5.1 1.8 1 1 1 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.21 KEZ46331.1 - 0.09 12.5 13.5 0.085 12.6 2.4 2.7 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Glyco_transf_28 PF03033.20 KEZ46332.1 - 3.7e-22 78.9 0.0 7.4e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain VPS13_C PF16909.5 KEZ46332.1 - 0.0023 17.7 0.4 0.0066 16.2 0.2 1.9 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal UDPGT PF00201.18 KEZ46332.1 - 0.0049 15.7 0.0 0.0074 15.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase COX2-transmemb PF09125.10 KEZ46334.1 - 0.062 13.1 0.6 0.062 13.1 0.6 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Metallophos PF00149.28 KEZ46335.1 - 4.2e-24 86.2 0.1 3.3e-23 83.3 0.0 2.5 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase NACHT PF05729.12 KEZ46335.1 - 4.4e-09 36.5 0.2 2.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.6 KEZ46335.1 - 1e-08 35.5 0.3 0.00013 22.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ46335.1 - 3.1e-07 30.9 0.1 1.1e-06 29.2 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_16 PF13191.6 KEZ46335.1 - 3.6e-07 30.7 0.0 1.5e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KEZ46335.1 - 2.8e-05 24.8 0.1 7.4e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.6 KEZ46335.1 - 0.00077 19.7 0.0 0.0027 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ46335.1 - 0.0023 17.1 0.0 0.0056 15.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Ank_3 PF13606.6 KEZ46335.1 - 0.0025 18.1 0.2 9.1 7.2 0.0 4.5 3 0 0 3 3 3 1 Ankyrin repeat AAA_33 PF13671.6 KEZ46335.1 - 0.0027 17.9 0.0 0.019 15.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KEZ46335.1 - 0.0072 16.9 0.0 0.056 14.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain Ank_5 PF13857.6 KEZ46335.1 - 0.0075 16.6 0.2 0.025 14.9 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NTPase_1 PF03266.15 KEZ46335.1 - 0.011 15.7 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 NTPase AAA PF00004.29 KEZ46335.1 - 0.011 16.2 0.0 0.044 14.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.14 KEZ46335.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Mqo PF06039.15 KEZ46335.1 - 0.035 12.7 0.0 0.054 12.0 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Ank PF00023.30 KEZ46335.1 - 0.047 14.2 3.1 1.2 9.7 0.2 4.0 4 0 0 4 4 3 0 Ankyrin repeat Hydrolase_4 PF12146.8 KEZ46335.1 - 0.071 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 EF1_GNE PF00736.19 KEZ46336.1 - 1.1e-29 102.4 0.6 1.6e-29 101.9 0.6 1.2 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KEZ46336.1 - 7e-12 45.6 6.6 1.6e-11 44.4 6.6 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region RabGAP-TBC PF00566.18 KEZ46337.1 - 3e-32 112.0 0.0 5.1e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KEZ46337.1 - 1.6e-08 33.3 0.5 4e-08 32.0 0.5 1.6 1 0 0 1 1 1 1 SBE2, cell-wall formation PBP1_TM PF14812.6 KEZ46337.1 - 7.3 7.0 8.6 24 5.4 1.0 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cpn60_TCP1 PF00118.24 KEZ46338.1 - 8.9e-143 476.5 9.9 1e-142 476.3 9.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KEZ46338.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat eIF2A PF08662.11 KEZ46339.1 - 3e-38 131.6 3.0 2.1e-35 122.4 0.3 4.0 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KEZ46339.1 - 6.2e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KEZ46339.1 - 0.11 13.4 5.1 8.8 7.4 0.0 4.9 5 1 0 5 5 5 0 WD domain, G-beta repeat DUF4467 PF14729.6 KEZ46339.1 - 0.12 12.8 0.6 0.92 9.9 0.0 2.7 4 0 0 4 4 4 0 Domain of unknown function with cystatin-like fold (DUF4467) PRP3 PF08572.10 KEZ46339.1 - 1.6 8.4 5.1 5.9 6.6 5.1 2.0 1 1 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) FA_desaturase PF00487.24 KEZ46340.1 - 3.4e-24 86.1 19.5 6.6e-24 85.1 19.5 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KEZ46340.1 - 8.7e-06 26.0 0.0 3e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) zf-C3HC4_3 PF13920.6 KEZ46341.1 - 1.1e-06 28.4 9.6 1.1e-06 28.4 9.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ46341.1 - 0.0036 17.1 11.3 0.0036 17.1 11.3 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KEZ46341.1 - 0.021 15.2 11.1 0.021 15.2 11.1 3.1 4 0 0 4 4 4 0 Ring finger domain SWIB PF02201.18 KEZ46342.1 - 9.7e-31 105.5 1.1 2.5e-30 104.2 1.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KEZ46342.1 - 1.4e-16 60.1 3.0 2.3e-16 59.4 1.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain SRP54_N PF02881.19 KEZ46342.1 - 0.083 13.1 0.5 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain DTHCT PF08070.11 KEZ46342.1 - 0.11 13.2 18.7 0.45 11.3 2.4 2.4 1 1 1 2 2 2 0 DTHCT (NUC029) region SRP-alpha_N PF04086.13 KEZ46342.1 - 0.15 11.9 8.7 0.19 11.6 8.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pap_E4 PF02711.14 KEZ46342.1 - 0.58 11.2 6.4 7 7.7 0.2 2.4 2 0 0 2 2 2 0 E4 protein Ank_2 PF12796.7 KEZ46343.1 - 5.7e-99 324.9 0.0 9.5e-19 67.8 0.0 8.9 3 3 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ46343.1 - 1.3e-76 252.1 9.4 1.4e-08 35.1 0.0 16.6 5 4 12 17 17 17 14 Ankyrin repeats (many copies) Ank PF00023.30 KEZ46343.1 - 3.1e-71 232.9 0.5 3.8e-06 27.1 0.0 17.8 18 1 0 18 18 18 15 Ankyrin repeat Ank_3 PF13606.6 KEZ46343.1 - 2.4e-68 217.9 0.3 0.00031 20.9 0.0 19.1 19 0 0 19 19 19 13 Ankyrin repeat Ank_5 PF13857.6 KEZ46343.1 - 1.3e-64 213.4 11.1 1.3e-10 41.3 0.1 14.5 7 3 7 14 14 14 12 Ankyrin repeats (many copies) CorA PF01544.18 KEZ46343.1 - 1.2e-06 28.0 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CHCH PF06747.13 KEZ46344.1 - 1e-05 25.5 2.3 2.1e-05 24.5 2.3 1.6 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KEZ46344.1 - 0.00061 20.0 1.8 0.00091 19.4 1.8 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 KEZ46344.1 - 0.0044 17.3 1.9 0.0067 16.7 1.9 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NatB_MDM20 PF09797.9 KEZ46345.1 - 1e-41 143.2 0.0 2.9e-41 141.7 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit SapB_1 PF05184.15 KEZ46345.1 - 0.044 13.8 0.3 0.7 10.0 0.1 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 Ilm1 PF10311.9 KEZ46346.1 - 1.4e-69 233.0 0.8 1.6e-69 232.7 0.8 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 SVM_signal PF12113.8 KEZ46346.1 - 0.21 11.5 1.4 0.52 10.3 1.4 1.6 1 0 0 1 1 1 0 SVM protein signal sequence Prenyltrans PF00432.21 KEZ46347.1 - 6.7e-32 108.9 9.5 8.2e-07 28.7 0.0 5.9 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KEZ46347.1 - 0.06 12.4 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KEZ46347.1 - 0.087 11.9 0.1 0.22 10.6 0.1 1.7 1 1 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Pkinase PF00069.25 KEZ46348.1 - 2.6e-65 220.4 0.0 3.6e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46348.1 - 4.8e-40 137.5 0.0 7.1e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ46348.1 - 1.6e-07 30.9 0.0 5.8e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KEZ46348.1 - 0.00015 21.8 4.4 0.031 14.2 0.1 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KEZ46348.1 - 0.00019 20.5 0.0 0.00019 20.5 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KEZ46348.1 - 0.11 11.9 2.8 0.26 10.6 0.0 2.4 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KEZ46348.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TRAPPC10 PF12584.8 KEZ46349.1 - 2.3e-21 76.1 0.0 4.3e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KEZ46349.1 - 0.011 15.3 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Ribosomal_L12_N PF16320.5 KEZ46349.1 - 0.29 10.9 1.3 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain IF-2B PF01008.17 KEZ46350.1 - 5e-80 268.7 0.7 5.9e-80 268.5 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.28 KEZ46351.1 - 1.7e-21 76.9 0.1 2.5e-20 73.1 0.1 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KEZ46351.1 - 1.1e-18 67.2 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KEZ46351.1 - 0.00045 20.0 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 NDUF_B8 PF05821.11 KEZ46353.1 - 1.6e-07 31.3 3.2 2.5e-07 30.7 3.2 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF2205 PF10224.9 KEZ46354.1 - 1.7e-36 124.1 1.0 2.3e-36 123.6 1.0 1.2 1 0 0 1 1 1 1 Short coiled-coil protein AAA_32 PF13654.6 KEZ46354.1 - 0.025 13.4 0.0 0.026 13.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 KEZ46355.1 - 3.7e-24 85.3 26.0 2.7e-16 59.5 8.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily 7tm_2 PF00002.24 KEZ46356.1 - 3.7e-11 42.8 10.1 3.7e-11 42.8 10.1 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KEZ46356.1 - 6e-09 35.5 16.3 7.5e-09 35.1 10.7 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KEZ46356.1 - 4.3e-08 33.2 11.9 7.6e-08 32.4 11.9 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KEZ46356.1 - 1.3e-06 27.9 3.4 1.9e-06 27.4 3.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 KEZ46356.1 - 0.0092 15.1 11.6 0.21 10.6 11.6 2.1 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Peptidase_M56 PF05569.11 KEZ46356.1 - 0.35 10.0 1.8 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 STE3 PF02076.15 KEZ46356.1 - 7.5 5.7 20.7 5.5 6.1 16.7 2.5 2 1 0 2 2 2 0 Pheromone A receptor zf_C2H2_10 PF18414.1 KEZ46358.1 - 0.0025 17.3 1.8 0.0025 17.3 1.8 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger zf-C2H2_4 PF13894.6 KEZ46358.1 - 0.01 16.6 1.8 0.067 14.1 0.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KEZ46358.1 - 0.023 15.1 1.0 0.073 13.6 1.0 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Evr1_Alr PF04777.13 KEZ46359.1 - 4.3e-25 88.1 0.0 6.7e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.26 KEZ46360.1 - 7.3e-47 159.3 0.3 8.5e-47 159.1 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Dot_icm_IcmQ PF09475.10 KEZ46361.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Cyclin PF08613.11 KEZ46362.1 - 1e-42 146.2 3.6 7.3e-25 88.2 0.1 2.6 2 0 0 2 2 2 2 Cyclin Cwf_Cwc_15 PF04889.12 KEZ46362.1 - 6.6e-05 22.8 4.9 0.00011 22.0 4.9 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 KEZ46362.1 - 0.32 10.4 5.7 0.69 9.3 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FAM176 PF14851.6 KEZ46362.1 - 0.63 9.7 4.1 5.3 6.7 3.4 2.3 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 KEZ46362.1 - 1.1 9.7 8.8 2.4 8.6 8.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 KEZ46362.1 - 1.4 8.2 10.8 2.2 7.5 10.8 1.2 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 KEZ46362.1 - 3.1 8.5 13.6 11 6.7 13.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Acetyltransf_2 PF00797.17 KEZ46363.1 - 2.2e-35 122.6 0.0 6.2e-34 117.8 0.0 2.8 1 1 1 2 2 2 1 N-acetyltransferase YbjQ_1 PF01906.17 KEZ46364.1 - 3.8e-28 98.2 0.1 4.6e-28 97.9 0.1 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.21 KEZ46365.1 - 7.1e-98 327.6 0.2 9.4e-98 327.2 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KEZ46365.1 - 1.4e-54 184.8 0.7 2.8e-54 183.8 0.4 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KEZ46365.1 - 0.00084 19.0 0.8 0.0049 16.5 0.3 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KEZ46365.1 - 0.018 14.3 0.2 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ46365.1 - 0.028 15.0 0.8 0.028 15.0 0.8 3.2 2 2 1 3 3 3 0 Alpha/beta hydrolase family DLH PF01738.18 KEZ46365.1 - 0.092 12.3 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Clathrin PF00637.20 KEZ46366.1 - 1.8e-195 640.7 26.0 4.6e-32 110.9 1.9 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 KEZ46366.1 - 5.2e-32 109.6 0.7 2.9e-31 107.2 0.1 2.7 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 KEZ46366.1 - 1.5e-25 88.2 0.3 4.3e-05 23.6 0.0 6.5 6 0 0 6 6 6 5 Clathrin propeller repeat TPR_7 PF13176.6 KEZ46366.1 - 0.0009 19.1 2.8 1.2e+02 3.1 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46366.1 - 0.0077 17.0 10.9 20 6.3 0.0 8.0 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46366.1 - 0.0087 16.2 6.0 0.5 10.7 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Clathrin-link PF09268.10 KEZ46366.1 - 0.013 14.9 0.7 0.037 13.4 0.7 1.9 1 0 0 1 1 1 0 Clathrin, heavy-chain linker XPC-binding PF09280.11 KEZ46366.1 - 0.11 12.3 0.5 18 5.2 0.0 3.5 3 0 0 3 3 3 0 XPC-binding domain VapB_antitoxin PF09957.9 KEZ46366.1 - 0.13 12.2 0.0 0.57 10.1 0.0 2.1 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Coatomer_WDAD PF04053.14 KEZ46366.1 - 0.43 9.6 6.7 2.3 7.2 0.3 4.0 5 0 0 5 5 5 0 Coatomer WD associated region TPR_1 PF00515.28 KEZ46366.1 - 0.48 10.3 5.2 12 5.9 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Vps39_1 PF10366.9 KEZ46366.1 - 1.1 9.6 4.4 20 5.5 0.0 4.9 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 KEZ46366.1 - 3.8 7.9 10.3 5.4 7.4 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46366.1 - 8.4 7.0 8.7 34 5.0 0.1 5.4 7 0 0 7 7 5 0 Tetratricopeptide repeat SET PF00856.28 KEZ46367.1 - 3.3e-14 53.6 0.0 2.2e-13 51.0 0.0 2.3 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 KEZ46367.1 - 0.00014 21.7 0.4 0.00014 21.7 0.4 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46367.1 - 0.00021 21.2 11.0 0.00033 20.6 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ46367.1 - 0.0012 18.6 5.9 0.11 12.4 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46367.1 - 0.0018 18.8 0.2 0.005 17.3 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46367.1 - 0.013 16.2 5.1 0.088 13.7 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ46367.1 - 0.31 11.4 6.3 0.41 11.0 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KEZ46367.1 - 1.9 8.6 4.2 0.7 10.0 0.5 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Hum_adeno_E3A PF05393.11 KEZ46368.1 - 0.0011 18.8 0.2 0.002 18.0 0.2 1.3 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein DUF4381 PF14316.6 KEZ46368.1 - 0.096 12.9 0.4 0.26 11.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 KEZ46368.1 - 0.2 11.6 1.4 0.78 9.6 0.0 2.1 2 1 0 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 KEZ46368.1 - 0.21 12.0 0.5 11 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Synaptobrevin PF00957.21 KEZ46368.1 - 7 6.5 5.8 11 5.9 5.8 1.2 1 0 0 1 1 1 0 Synaptobrevin RCR PF12273.8 KEZ46368.1 - 7.1 7.3 9.4 3.6 8.3 5.4 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red hDGE_amylase PF14701.6 KEZ46369.1 - 1.2e-156 522.2 0.0 1.6e-156 521.8 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KEZ46369.1 - 6.7e-122 407.1 0.0 9.7e-122 406.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KEZ46369.1 - 6.1e-84 281.6 0.0 1.3e-83 280.6 0.0 1.6 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KEZ46369.1 - 2.5e-28 98.0 0.0 5.4e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme NAD_Gly3P_dh_N PF01210.23 KEZ46370.1 - 4.7e-43 146.9 0.0 1.6e-42 145.1 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KEZ46370.1 - 9.3e-40 136.2 0.1 1.4e-39 135.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus BORCS6 PF10157.9 KEZ46371.1 - 0.23 11.7 1.6 0.87 9.8 0.0 2.6 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 FAM184 PF15665.5 KEZ46371.1 - 0.9 9.3 5.5 0.17 11.7 1.2 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Pam17 PF08566.10 KEZ46372.1 - 2.5e-63 212.9 0.0 3.3e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ThiF PF00899.21 KEZ46373.1 - 9.7e-34 116.8 1.4 5e-22 78.4 0.0 2.2 1 1 1 2 2 2 2 ThiF family Rhodanese PF00581.20 KEZ46373.1 - 1.8e-09 38.1 0.0 3.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox PF00070.27 KEZ46373.1 - 0.011 16.2 0.1 0.033 14.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KEZ46373.1 - 0.023 14.0 0.5 0.035 13.3 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain ZapB PF06005.12 KEZ46373.1 - 0.058 13.8 1.5 0.099 13.1 1.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Pyr_redox_2 PF07992.14 KEZ46373.1 - 0.07 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3847 PF12958.7 KEZ46373.1 - 0.33 11.1 2.0 0.58 10.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) SLX9 PF15341.6 KEZ46374.1 - 2.9e-35 121.5 0.6 3.8e-35 121.1 0.2 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Peptidase_C48 PF02902.19 KEZ46375.1 - 1.1e-16 61.3 0.0 4.5e-16 59.3 0.0 2.0 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain NAAA-beta PF15508.6 KEZ46376.1 - 2.2e-13 50.3 0.2 1.2e-12 48.0 0.1 2.1 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MFS_1 PF07690.16 KEZ46377.1 - 4.2e-35 121.3 60.9 2.7e-33 115.3 57.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KEZ46378.1 - 6.3e-27 94.4 0.0 1.5e-26 93.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46378.1 - 2.6e-06 27.4 10.8 5e-06 26.5 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNR_4 PF15892.5 KEZ46379.1 - 3.1e-76 256.3 5.1 3.8e-76 256.0 5.1 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member SKG6 PF08693.10 KEZ46380.1 - 0.018 14.4 4.9 0.035 13.5 4.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.7 KEZ46380.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF347 PF03988.12 KEZ46380.1 - 0.048 13.8 0.8 0.084 13.1 0.8 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Gram_pos_anchor PF00746.21 KEZ46380.1 - 0.079 12.9 0.4 0.18 11.8 0.4 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 KEZ46382.1 - 3.4e-15 55.8 17.6 3.4e-15 55.8 17.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 KEZ46383.1 - 4.6e-64 216.8 0.8 5.6e-64 216.5 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.22 KEZ46384.1 - 2.9e-72 243.9 0.0 4.4e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KEZ46385.1 - 5.6e-57 193.5 0.0 7.1e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 B12D PF06522.11 KEZ46385.1 - 0.41 10.5 1.3 9.3 6.1 0.7 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Fungal_trans PF04082.18 KEZ46386.1 - 9.9e-05 21.5 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGA2 PF07543.12 KEZ46386.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 AMP-binding PF00501.28 KEZ46387.1 - 2.8e-55 187.6 0.0 3.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KEZ46387.1 - 0.0081 17.1 0.0 0.02 15.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myco_arth_vir_N PF09610.10 KEZ46387.1 - 0.69 10.1 5.2 1.9 8.6 5.2 1.8 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Fungal_trans PF04082.18 KEZ46388.1 - 4.5e-11 42.3 0.2 6.5e-11 41.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ46389.1 - 1.2e-30 106.6 22.3 8.7e-30 103.8 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KEZ46389.1 - 0.12 12.2 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SKG6 PF08693.10 KEZ46390.1 - 0.071 12.5 1.1 0.18 11.3 1.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UPF0697 PF15117.6 KEZ46390.1 - 0.15 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 HMGL-like PF00682.19 KEZ46392.1 - 2e-34 119.4 0.0 3.9e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Fungal_trans PF04082.18 KEZ46392.1 - 8.2e-18 64.4 0.0 1.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KEZ46392.1 - 8.2e-09 35.1 0.1 4.1e-08 32.8 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KEZ46392.1 - 2.6e-07 30.4 0.0 8e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Zn_clus PF00172.18 KEZ46392.1 - 3.3e-07 30.3 10.2 6.4e-07 29.4 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phasin PF05597.11 KEZ46392.1 - 0.2 11.7 0.3 1.5 8.8 0.3 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Biotin_carb_N PF00289.22 KEZ46393.1 - 1.2e-36 125.6 0.1 2.1e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CPSase_L_D2 PF02786.17 KEZ46393.1 - 1.3e-18 67.3 0.1 2e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 KEZ46393.1 - 0.0024 17.5 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KEZ46393.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KEZ46393.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Ldi PF18566.1 KEZ46394.1 - 3.5e-136 453.9 0.0 4.8e-136 453.4 0.0 1.2 1 0 0 1 1 1 1 Linalool dehydratase/isomerase DUF4979 PF16351.5 KEZ46394.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4979) Aldedh PF00171.22 KEZ46395.1 - 5.7e-140 466.9 0.0 9.6e-140 466.1 0.0 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family ADH_zinc_N PF00107.26 KEZ46396.1 - 3.9e-23 81.9 0.3 1.2e-22 80.2 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KEZ46396.1 - 1.5e-08 34.4 0.1 3.8e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KEZ46396.1 - 7.8e-05 22.2 1.0 0.00012 21.7 1.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KEZ46396.1 - 0.0018 17.6 2.9 0.0031 16.9 2.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KEZ46396.1 - 0.035 13.5 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KEZ46396.1 - 0.058 13.7 0.4 0.12 12.7 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain ADH_zinc_N_2 PF13602.6 KEZ46396.1 - 0.15 13.2 0.0 0.3 12.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_hydro_61 PF03443.14 KEZ46397.1 - 2.6e-59 200.6 0.0 3.1e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4690 PF15756.5 KEZ46398.1 - 0.027 15.1 0.1 0.074 13.7 0.1 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage PTP_tm PF18861.1 KEZ46398.1 - 0.04 13.9 0.2 0.066 13.2 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Nitrate_red_gam PF02665.14 KEZ46398.1 - 0.048 13.2 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Gram_pos_anchor PF00746.21 KEZ46398.1 - 0.21 11.6 2.8 0.41 10.6 2.8 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ABC_tran PF00005.27 KEZ46399.1 - 1.1e-35 123.2 0.1 1.6e-17 64.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_22 PF13401.6 KEZ46399.1 - 3.7e-08 33.7 0.8 0.0022 18.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 KEZ46399.1 - 4e-08 33.0 0.4 0.00066 19.2 0.3 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ46399.1 - 1.5e-07 31.6 2.4 0.0018 18.2 0.6 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 KEZ46399.1 - 8.6e-06 25.6 21.2 0.051 13.2 0.8 4.4 2 2 2 4 4 4 3 ABC transporter transmembrane region T2SSE PF00437.20 KEZ46399.1 - 9.9e-06 24.8 3.1 0.012 14.6 0.3 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KEZ46399.1 - 1.5e-05 25.0 0.9 0.018 14.9 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 KEZ46399.1 - 1.8e-05 24.4 0.2 0.23 11.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KEZ46399.1 - 2e-05 24.3 0.2 0.027 14.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 KEZ46399.1 - 4e-05 23.8 0.2 0.31 11.3 0.0 3.9 4 1 0 4 4 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KEZ46399.1 - 0.00026 21.4 1.2 0.32 11.4 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KEZ46399.1 - 0.00027 20.6 1.8 0.003 17.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KEZ46399.1 - 0.00046 20.1 0.3 1.5 8.7 0.1 2.8 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.18 KEZ46399.1 - 0.0017 17.8 0.4 0.0066 15.8 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 KEZ46399.1 - 0.0033 17.2 0.0 7 6.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 KEZ46399.1 - 0.0034 17.8 0.3 0.42 11.0 0.0 3.5 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KEZ46399.1 - 0.0038 16.8 1.7 1 8.9 0.3 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KEZ46399.1 - 0.004 17.1 0.2 3.7 7.6 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KEZ46399.1 - 0.0061 16.7 0.3 3.1 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KEZ46399.1 - 0.0068 15.8 0.4 1.3 8.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 KEZ46399.1 - 0.0093 14.9 2.9 2.1 7.2 0.1 3.2 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.23 KEZ46399.1 - 0.038 14.1 2.7 5.8 7.0 0.4 2.9 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 KEZ46399.1 - 0.038 14.4 0.5 9.8 6.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Sigma54_activat PF00158.26 KEZ46399.1 - 0.038 13.7 0.0 5.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.29 KEZ46399.1 - 0.051 13.4 0.3 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase MobB PF03205.14 KEZ46399.1 - 0.068 13.1 1.4 4.1 7.3 0.2 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 KEZ46399.1 - 0.084 12.1 0.8 8.8 5.5 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 KEZ46399.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 KEZ46399.1 - 0.092 12.6 0.4 0.63 9.9 0.1 2.4 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.12 KEZ46399.1 - 0.093 12.2 1.6 0.82 9.1 0.3 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_24 PF13479.6 KEZ46399.1 - 0.11 12.2 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KEZ46399.1 - 0.15 12.1 2.4 0.88 9.6 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 KEZ46399.1 - 0.23 11.9 1.2 0.32 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 KEZ46399.1 - 0.62 10.3 4.5 41 4.4 0.2 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 KEZ46400.1 - 1.2e-11 44.2 3.8 1.1e-10 41.0 0.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ46400.1 - 8.6e-07 28.2 1.7 1.7e-06 27.2 1.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KEZ46400.1 - 0.00063 18.7 0.0 0.00077 18.4 0.0 1.3 1 1 0 1 1 1 1 MFS_1 like family Acyl_transf_3 PF01757.22 KEZ46400.1 - 0.026 13.6 1.1 0.026 13.6 1.1 1.8 3 0 0 3 3 3 0 Acyltransferase family DUF2723 PF11028.8 KEZ46400.1 - 0.041 13.8 0.9 4 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) GPR15L PF15854.5 KEZ46401.1 - 0.0072 16.5 0.5 0.0084 16.3 0.5 1.1 1 0 0 1 1 1 1 G-protein coupled receptor ligand 15 DegT_DnrJ_EryC1 PF01041.17 KEZ46402.1 - 2.2e-18 66.7 0.0 1.4e-13 50.9 0.0 2.3 1 1 1 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family ABC_membrane PF00664.23 KEZ46403.1 - 1.5e-14 54.3 0.6 1.8e-14 54.0 0.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Cas_Cmr5 PF09701.10 KEZ46403.1 - 0.0082 16.4 0.0 0.0087 16.4 0.0 1.3 1 1 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr5) Pectate_lyase_3 PF12708.7 KEZ46404.1 - 9.1e-32 110.6 4.0 3.7e-20 72.7 0.2 3.3 2 1 1 3 3 3 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 KEZ46404.1 - 3.7e-05 23.3 1.7 0.055 13.2 0.2 3.2 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Ecm33 PF12454.8 KEZ46405.1 - 0.036 14.2 1.0 0.08 13.1 1.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein LysM PF01476.20 KEZ46406.1 - 3.5e-40 135.8 13.9 3.2e-08 33.5 0.3 5.2 5 0 0 5 5 5 5 LysM domain HTH_28 PF13518.6 KEZ46406.1 - 3.2e-05 23.9 0.0 3.4 7.9 0.0 4.4 5 0 0 5 5 5 1 Helix-turn-helix domain HTH_23 PF13384.6 KEZ46406.1 - 0.003 17.3 0.1 46 4.0 0.0 4.2 4 0 0 4 4 4 0 Homeodomain-like domain SurA_N PF09312.11 KEZ46406.1 - 0.0063 16.6 0.5 38 4.4 0.0 3.9 4 0 0 4 4 4 0 SurA N-terminal domain DUF2960 PF11173.8 KEZ46406.1 - 0.018 15.5 0.0 31 5.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2960) UPF0203 PF05254.12 KEZ46406.1 - 0.034 14.4 4.4 3 8.2 0.4 3.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) HTH_Tnp_1 PF01527.20 KEZ46406.1 - 0.083 13.2 0.0 10 6.5 0.0 3.4 4 0 0 4 4 4 0 Transposase Aldo_ket_red PF00248.21 KEZ46407.1 - 2.9e-48 164.6 0.0 1.1e-47 162.6 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family NACHT PF05729.12 KEZ46408.1 - 1e-09 38.5 0.0 2.7e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KEZ46408.1 - 1.9e-09 37.7 0.7 0.002 18.4 0.0 5.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 KEZ46408.1 - 1.3e-05 25.6 0.1 9.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain WD40 PF00400.32 KEZ46408.1 - 0.00075 20.3 2.2 32 5.6 0.0 6.4 6 0 0 6 6 6 0 WD domain, G-beta repeat NB-ARC PF00931.22 KEZ46408.1 - 0.0017 17.6 0.0 0.004 16.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KEZ46408.1 - 0.0063 16.8 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KEZ46408.1 - 0.0083 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 KEZ46408.1 - 0.026 14.9 0.1 0.093 13.1 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 KEZ46408.1 - 0.038 13.6 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KEZ46408.1 - 0.041 14.1 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KEZ46408.1 - 0.057 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KEZ46408.1 - 0.058 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 KEZ46408.1 - 0.065 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 KEZ46408.1 - 0.092 13.2 0.2 0.24 11.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KEZ46408.1 - 0.098 11.6 0.0 0.24 10.3 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 KEZ46408.1 - 0.1 11.8 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 KEZ46408.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KEZ46408.1 - 0.13 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KEZ46408.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 KEZ46408.1 - 0.16 11.7 0.1 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain RdRP PF05183.12 KEZ46410.1 - 3.5e-124 415.6 0.0 4.5e-124 415.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fungal_trans PF04082.18 KEZ46412.1 - 4.6e-16 58.6 1.2 7.4e-16 58.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46412.1 - 1.2e-08 34.9 12.0 2.6e-08 33.8 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_1 PF00232.18 KEZ46413.1 - 3.2e-97 325.8 0.4 1.3e-61 208.5 0.0 2.0 1 1 0 2 2 2 2 Glycosyl hydrolase family 1 Sugar_tr PF00083.24 KEZ46414.1 - 5.6e-78 262.8 17.7 6.9e-78 262.5 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ46414.1 - 3.5e-21 75.5 20.9 3.5e-21 75.5 20.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily HlyIII PF03006.20 KEZ46414.1 - 0.4 10.4 13.6 2.5 7.8 5.5 2.4 2 0 0 2 2 2 0 Haemolysin-III related IU_nuc_hydro PF01156.19 KEZ46415.1 - 1.9e-72 244.4 0.2 2.4e-72 244.1 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Abhydrolase_4 PF08386.10 KEZ46416.1 - 7e-21 74.3 0.0 1.2e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KEZ46416.1 - 1.4e-17 64.2 0.0 1.1e-08 35.0 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Glyco_hydro_125 PF06824.11 KEZ46417.1 - 1.9e-154 514.5 0.1 1.7e-151 504.8 0.1 2.0 1 1 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) AAA PF00004.29 KEZ46418.1 - 3.7e-54 182.7 0.0 3.2e-43 147.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KEZ46418.1 - 7.6e-27 93.6 0.4 2.2e-26 92.1 0.4 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KEZ46418.1 - 4.2e-16 58.5 0.5 1.9e-10 40.3 0.2 2.7 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KEZ46418.1 - 6.7e-10 39.6 1.7 0.0041 17.5 0.0 4.3 2 2 2 4 4 4 2 AAA ATPase domain NACHT PF05729.12 KEZ46418.1 - 2.8e-07 30.6 0.3 0.00037 20.5 0.0 3.3 3 1 0 3 3 3 1 NACHT domain TsaE PF02367.17 KEZ46418.1 - 7.6e-06 25.9 0.0 0.018 15.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KEZ46418.1 - 1.2e-05 25.9 0.0 0.039 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KEZ46418.1 - 1.4e-05 25.3 0.0 0.27 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KEZ46418.1 - 2.2e-05 24.0 0.0 0.001 18.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KEZ46418.1 - 2.7e-05 24.2 0.0 0.043 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KEZ46418.1 - 2.8e-05 24.1 0.2 0.13 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KEZ46418.1 - 3e-05 24.3 0.7 0.43 10.9 0.0 3.7 2 2 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KEZ46418.1 - 5e-05 23.1 0.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KEZ46418.1 - 7.1e-05 23.0 0.0 0.26 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 KEZ46418.1 - 0.00057 19.1 0.0 0.013 14.7 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 KEZ46418.1 - 0.0016 19.0 0.0 0.81 10.2 0.0 2.9 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 KEZ46418.1 - 0.0019 17.5 0.0 0.74 9.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 KEZ46418.1 - 0.004 17.5 0.0 5.1 7.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KEZ46418.1 - 0.0054 16.3 4.5 1.4 8.5 0.1 4.1 2 2 0 4 4 4 1 AAA domain AAA_28 PF13521.6 KEZ46418.1 - 0.0061 16.8 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KEZ46418.1 - 0.01 15.1 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KEZ46418.1 - 0.012 15.3 0.1 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEZ46418.1 - 0.016 14.6 0.1 0.79 9.1 0.1 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 KEZ46418.1 - 0.023 14.6 0.0 0.89 9.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KEZ46418.1 - 0.026 13.9 0.0 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 KEZ46418.1 - 0.037 14.0 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 KEZ46418.1 - 0.054 13.2 0.1 0.57 10.0 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KEZ46418.1 - 0.068 12.9 0.0 4.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 KEZ46418.1 - 0.069 13.6 0.1 2.5 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KEZ46418.1 - 0.091 12.5 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SKI PF01202.22 KEZ46418.1 - 0.1 12.7 0.0 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase FtsK_SpoIIIE PF01580.18 KEZ46418.1 - 0.12 11.7 0.1 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family PEX-2N PF09263.10 KEZ46418.1 - 0.15 12.4 0.2 1.3 9.4 0.0 2.6 2 1 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal dNK PF01712.19 KEZ46418.1 - 0.15 11.8 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 KEZ46418.1 - 0.25 10.9 1.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 KEZ46419.1 - 8.4e-104 345.5 0.0 1.3e-103 344.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEZ46419.1 - 1.3e-29 102.6 1.9 2.4e-29 101.7 1.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEZ46419.1 - 7.2e-20 71.2 1.5 1.6e-19 70.1 1.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KEZ46419.1 - 5.9e-17 62.2 1.9 1.8e-16 60.6 1.9 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KEZ46419.1 - 1.4e-07 31.1 0.0 1.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KEZ46419.1 - 3e-06 27.3 0.0 9.5e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KEZ46419.1 - 0.0075 16.1 0.1 0.029 14.2 0.1 2.0 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 KEZ46419.1 - 0.021 15.5 2.9 0.087 13.5 0.5 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KEZ46419.1 - 0.027 14.3 0.0 0.1 12.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEZ46419.1 - 0.14 11.9 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.9 KEZ46420.1 - 3.2e-83 279.5 0.0 4.1e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 CpcD PF01383.21 KEZ46421.1 - 0.15 12.3 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain RhoGAP PF00620.27 KEZ46423.1 - 4.7e-30 104.4 0.0 8.5e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.21 KEZ46424.1 - 1.8e-58 194.0 8.7 1.2e-12 47.3 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KEZ46424.1 - 7.3e-05 22.0 0.0 0.073 12.2 0.0 3.2 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain DUF2014 PF09427.10 KEZ46425.1 - 0.0071 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) MutS_V PF00488.21 KEZ46426.1 - 1.3e-68 230.8 0.3 6.7e-68 228.4 0.1 2.4 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KEZ46426.1 - 4.3e-35 121.7 1.4 8.7e-35 120.7 1.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KEZ46426.1 - 6.5e-28 97.2 0.0 1.3e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KEZ46426.1 - 1.2e-09 38.5 0.0 1.3e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KEZ46426.1 - 1.9e-06 28.1 0.0 4.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KEZ46426.1 - 0.0011 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) AAA_29 PF13555.6 KEZ46426.1 - 0.13 12.1 0.1 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ46426.1 - 0.16 12.5 0.2 2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FAR1 PF03101.15 KEZ46427.1 - 0.00019 22.0 1.0 0.00019 22.0 1.0 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 KEZ46427.1 - 0.11 13.0 0.4 0.11 13.0 0.4 2.4 2 1 0 2 2 2 0 Transcription factor AFT NAD_binding_9 PF13454.6 KEZ46428.1 - 6.1e-12 45.8 0.0 2.8e-10 40.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KEZ46428.1 - 2.1e-10 40.3 2.0 4.8e-08 32.6 1.6 3.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ46428.1 - 2.7e-09 36.7 0.2 0.00011 21.6 0.0 4.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ46428.1 - 3.3e-07 30.2 0.4 0.045 13.3 0.1 3.2 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ46428.1 - 1.5e-06 28.4 0.1 2.8e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KEZ46428.1 - 0.00027 21.5 0.1 3.7 8.2 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ46428.1 - 0.0017 17.6 0.1 0.02 14.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KEZ46428.1 - 0.0077 15.0 0.0 0.16 10.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KEZ46428.1 - 0.0092 15.3 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KEZ46428.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 KEZ46428.1 - 0.038 13.1 0.2 0.46 9.5 0.0 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KEZ46428.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Arginosuc_synth PF00764.19 KEZ46429.1 - 8.5e-142 473.0 0.0 9.8e-142 472.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KEZ46429.1 - 0.002 17.7 0.0 0.0063 16.0 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KEZ46429.1 - 0.098 11.4 0.0 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 tRNA methyl transferase RSN1_7TM PF02714.15 KEZ46431.1 - 6e-74 248.8 22.7 6e-74 248.8 22.7 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KEZ46431.1 - 2.6e-39 135.3 0.0 3.7e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KEZ46431.1 - 2.2e-35 121.8 0.8 2.2e-35 121.8 0.8 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport Streptin-Immun PF11083.8 KEZ46431.1 - 0.19 12.2 0.9 18 5.8 0.1 2.3 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein WD40 PF00400.32 KEZ46432.1 - 7.8e-57 187.9 38.7 3.1e-11 43.6 0.8 9.2 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KEZ46432.1 - 3.6e-20 72.1 7.7 3.7e-05 23.9 0.0 6.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KEZ46432.1 - 8.7e-07 28.2 0.0 0.19 10.7 0.0 4.5 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KEZ46432.1 - 7.6e-06 25.9 0.0 0.011 15.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KEZ46432.1 - 3.3e-05 23.7 0.3 0.23 11.5 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KEZ46432.1 - 0.00021 20.1 3.3 0.59 8.7 0.4 4.4 4 2 0 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 KEZ46432.1 - 0.0022 17.4 0.1 2.4 7.4 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal NLE PF08154.12 KEZ46432.1 - 0.011 16.3 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 NLE (NUC135) domain WD40_like PF17005.5 KEZ46432.1 - 0.027 13.8 0.0 0.93 8.8 0.0 3.1 4 0 0 4 4 4 0 WD40-like domain Proteasome_A_N PF10584.9 KEZ46432.1 - 0.045 13.4 0.1 15 5.4 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature 7TMR-DISM_7TM PF07695.11 KEZ46432.1 - 0.59 10.0 3.4 0.94 9.3 3.4 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Ank_2 PF12796.7 KEZ46433.1 - 6e-24 84.4 0.0 1.9e-08 34.8 0.0 4.0 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KEZ46433.1 - 1.1e-14 54.2 1.3 0.019 15.3 0.0 5.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 KEZ46433.1 - 1.8e-14 53.9 0.1 2.9e-05 24.5 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ46433.1 - 8.6e-14 50.3 1.4 0.1 13.2 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KEZ46433.1 - 3.2e-06 27.3 3.7 0.92 10.1 0.1 6.1 7 0 0 7 7 7 2 Ankyrin repeat MutS_V PF00488.21 KEZ46435.1 - 3.2e-63 213.2 0.2 4.6e-63 212.7 0.2 1.2 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 KEZ46435.1 - 1.1e-05 25.7 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 KEZ46435.1 - 2.7e-05 24.5 0.9 0.00082 19.7 0.1 2.3 2 0 0 2 2 2 1 MutS domain III AAA_27 PF13514.6 KEZ46435.1 - 0.014 15.0 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KEZ46435.1 - 0.085 12.3 0.1 3.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 GMC_oxred_N PF00732.19 KEZ46436.1 - 1.4e-29 103.4 0.0 1.3e-28 100.3 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ46436.1 - 1.3e-27 97.1 0.0 2.9e-27 96.0 0.0 1.6 2 0 0 2 2 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KEZ46436.1 - 0.00042 20.5 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ46436.1 - 0.00052 19.3 0.0 0.00091 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KEZ46436.1 - 0.0028 17.0 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ46436.1 - 0.006 15.7 0.9 0.0094 15.1 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KEZ46436.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KEZ46436.1 - 0.023 14.3 0.0 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KEZ46436.1 - 0.069 12.5 0.7 0.12 11.7 0.7 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KEZ46436.1 - 0.08 12.2 0.5 0.12 11.5 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain E3_binding PF02817.17 KEZ46436.1 - 0.089 13.2 1.8 6.2 7.3 0.0 2.9 2 1 0 2 2 2 0 e3 binding domain HI0933_like PF03486.14 KEZ46436.1 - 0.09 11.5 0.2 0.13 10.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Tyrosinase PF00264.20 KEZ46437.1 - 1.2e-51 176.1 2.1 2.2e-51 175.3 0.2 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KEZ46437.1 - 1e-32 113.4 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain WBS_methylT PF12589.8 KEZ46438.1 - 7.3e-15 55.5 4.7 1.3e-14 54.7 4.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KEZ46438.1 - 8.5e-11 42.4 0.0 1.4e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46438.1 - 5.1e-10 39.9 0.0 1e-09 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KEZ46438.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KEZ46438.1 - 0.00017 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46438.1 - 0.0004 21.1 0.0 0.0013 19.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ46438.1 - 0.0041 17.0 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEZ46438.1 - 0.0095 15.3 0.0 0.092 12.0 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KEZ46438.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KEZ46438.1 - 0.05 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 KEZ46438.1 - 0.087 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Erv26 PF04148.13 KEZ46439.1 - 2.8e-86 288.6 2.6 3.5e-86 288.3 2.6 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3169 PF11368.8 KEZ46439.1 - 1.6 8.2 5.8 1.5 8.3 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) Dynamin_N PF00350.23 KEZ46440.1 - 1.3e-32 113.2 0.7 6.8e-31 107.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KEZ46440.1 - 1e-13 51.2 0.0 3.8e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KEZ46440.1 - 8.3e-06 25.9 0.0 2.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KEZ46440.1 - 0.03 14.8 1.0 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 KEZ46440.1 - 0.24 11.6 1.2 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phe_tRNA-synt_N PF02912.18 KEZ46440.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain TMEM214 PF10151.9 KEZ46440.1 - 0.88 8.0 8.2 1.5 7.2 8.2 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Spt20 PF12090.8 KEZ46440.1 - 4.9 6.7 24.9 9.9 5.7 24.9 1.6 1 0 0 1 1 1 0 Spt20 family AAA_23 PF13476.6 KEZ46440.1 - 8.1 6.9 0.0 8.1 6.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain Aminotran_4 PF01063.19 KEZ46441.1 - 2.5e-24 86.4 0.0 3e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Thioredoxin_7 PF13899.6 KEZ46442.1 - 1.7e-17 63.4 0.0 5.4e-17 61.7 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KEZ46442.1 - 1e-14 54.0 0.3 2.7e-14 52.7 0.3 1.8 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KEZ46442.1 - 3.7e-07 30.3 0.0 9.2e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain CCDC50_N PF15295.6 KEZ46442.1 - 0.015 15.5 1.2 0.047 13.9 1.2 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Thioredox_DsbH PF03190.15 KEZ46442.1 - 0.035 14.1 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF255 CSN5_C PF18323.1 KEZ46442.1 - 0.11 13.4 0.4 0.4 11.6 0.4 1.9 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Pkinase PF00069.25 KEZ46443.1 - 5.4e-63 212.8 0.0 1.6e-31 109.6 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46443.1 - 1e-44 152.8 0.0 1.5e-24 86.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Ecm29 PF13001.7 KEZ46444.1 - 1.2e-139 466.2 0.0 8.8e-139 463.4 0.0 2.5 2 0 0 2 2 2 1 Proteasome stabiliser HEAT_EZ PF13513.6 KEZ46444.1 - 0.0002 21.8 6.4 9.8 6.8 0.0 7.5 5 1 1 6 6 6 1 HEAT-like repeat IFRD PF05004.13 KEZ46444.1 - 0.0073 15.4 0.1 6.9 5.7 0.0 3.9 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 KEZ46444.1 - 0.018 14.2 0.1 1.1 8.3 0.1 3.5 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 KEZ46444.1 - 0.034 14.4 7.2 94 3.7 0.0 7.5 7 0 0 7 7 7 0 HEAT repeat TAF6_C PF07571.13 KEZ46444.1 - 0.17 12.3 0.5 21 5.5 0.0 3.5 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain adh_short PF00106.25 KEZ46445.1 - 3.4e-30 105.0 0.0 2.7e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KEZ46445.1 - 3.7e-16 59.4 0.0 1.8e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KEZ46445.1 - 1.2e-05 25.3 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.19 KEZ46446.1 - 1e-12 48.0 0.7 3.6e-05 23.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 KEZ46446.1 - 1.1e-09 38.0 0.2 0.00035 19.9 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KEZ46446.1 - 3.1e-06 26.6 0.1 5.7e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KEZ46446.1 - 4.5e-05 23.6 0.1 0.00018 21.7 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ46446.1 - 9.4e-05 22.1 0.4 0.0035 17.0 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KEZ46446.1 - 0.00011 21.1 0.1 0.0053 15.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KEZ46446.1 - 0.00025 20.5 0.0 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KEZ46446.1 - 0.00029 21.3 0.3 0.069 13.7 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KEZ46446.1 - 0.0015 17.7 0.2 0.0038 16.3 0.2 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KEZ46446.1 - 0.032 13.5 0.0 5.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KEZ46446.1 - 0.033 13.4 0.1 0.53 9.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ46446.1 - 0.042 12.9 0.1 8 5.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein p450 PF00067.22 KEZ46447.1 - 5e-61 206.8 0.0 6.9e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Iso_dh PF00180.20 KEZ46448.1 - 8.7e-82 275.0 0.0 1e-81 274.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1157 PF06636.11 KEZ46448.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) C9orf72-like PF15019.6 KEZ46449.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 1 0 1 1 1 0 C9orf72-like protein family CBS PF00571.28 KEZ46450.1 - 5.4e-06 26.8 0.2 0.28 11.6 0.0 3.0 2 1 1 3 3 3 3 CBS domain Mito_carr PF00153.27 KEZ46451.1 - 1.8e-48 162.4 4.6 2.6e-17 62.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Patatin PF01734.22 KEZ46452.1 - 2.8e-19 70.1 1.1 6.7e-19 68.9 1.1 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase zf-RING_UBOX PF13445.6 KEZ46452.1 - 0.00012 22.1 3.6 0.00028 20.8 3.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEZ46452.1 - 0.0056 16.6 1.5 0.013 15.4 1.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KEZ46452.1 - 0.014 15.7 3.4 0.035 14.5 3.4 1.7 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 KEZ46452.1 - 0.032 14.1 3.2 0.071 13.0 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KEZ46452.1 - 0.12 12.3 2.5 0.28 11.1 2.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KEZ46452.1 - 1.8 8.4 7.8 0.39 10.6 3.2 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 KEZ46453.1 - 3.8e-41 141.3 0.0 3.8e-41 141.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KEZ46453.1 - 9.4e-19 68.1 0.1 1.6e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EMC3_TMCO1 PF01956.16 KEZ46453.1 - 0.33 10.7 6.0 0.6 9.8 6.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Borrelia_P83 PF05262.11 KEZ46453.1 - 2.2 6.7 12.2 3.3 6.1 12.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_C98 PF15499.6 KEZ46453.1 - 2.7 7.4 12.2 0.15 11.5 0.4 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_transf_22 PF03901.17 KEZ46454.1 - 3.5e-42 145.1 15.5 4.3e-42 144.8 15.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 KEZ46454.1 - 0.0025 18.1 11.5 0.0025 18.1 11.5 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PP2C PF00481.21 KEZ46455.1 - 6.5e-54 183.3 0.0 1e-53 182.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KEZ46455.1 - 6.4e-40 134.7 72.0 2.1e-09 37.0 0.4 10.1 4 3 8 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 KEZ46455.1 - 6.5e-32 109.0 73.0 0.00033 21.0 6.3 13.1 10 1 5 15 15 15 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 KEZ46455.1 - 5.5e-31 107.6 0.1 3.3e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 KEZ46455.1 - 8.6e-14 51.0 0.5 2e-13 49.8 0.5 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 KEZ46455.1 - 7.3e-09 35.4 24.8 0.031 13.8 0.4 4.5 2 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KEZ46455.1 - 1.3e-05 25.0 50.9 0.95 10.3 0.2 16.0 17 1 0 17 17 17 2 Leucine Rich Repeat LRR_6 PF13516.6 KEZ46455.1 - 0.002 18.0 44.4 1.9 8.7 0.0 12.8 14 0 0 14 14 14 4 Leucine Rich repeat LRR_5 PF13306.6 KEZ46455.1 - 0.14 12.1 2.0 0.83 9.6 0.1 2.9 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Pkinase PF00069.25 KEZ46456.1 - 3.9e-24 85.4 0.0 6.2e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46456.1 - 0.00029 20.2 0.0 0.029 13.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ46456.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RTC4 PF14474.6 KEZ46457.1 - 3.4e-32 111.1 0.0 6.8e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain zf-ribbon_3 PF13248.6 KEZ46457.1 - 0.11 12.0 0.4 0.22 11.0 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Dynamitin PF04912.14 KEZ46458.1 - 5.5e-97 325.5 6.6 6.6e-97 325.3 6.6 1.1 1 0 0 1 1 1 1 Dynamitin DUF724 PF05266.14 KEZ46458.1 - 0.00018 21.4 5.9 0.0014 18.5 0.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 KEZ46458.1 - 0.0041 17.2 4.5 0.037 14.1 0.3 3.1 3 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus FH2 PF02181.23 KEZ46458.1 - 0.0045 16.1 3.8 0.22 10.6 0.0 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain KxDL PF10241.9 KEZ46458.1 - 0.005 17.1 1.9 1.3 9.4 0.2 3.4 3 0 0 3 3 3 1 Uncharacterized conserved protein THOC7 PF05615.13 KEZ46458.1 - 0.011 16.1 2.2 0.011 16.1 2.2 2.8 2 1 0 2 2 2 0 Tho complex subunit 7 DHR10 PF18595.1 KEZ46458.1 - 0.024 14.7 2.9 0.024 14.7 2.9 3.2 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain ApoLp-III PF07464.11 KEZ46458.1 - 0.046 13.8 3.7 0.28 11.2 0.1 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 KEZ46458.1 - 0.11 12.9 8.0 1.2 9.5 0.3 4.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynein_heavy PF03028.15 KEZ46458.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain DUF1664 PF07889.12 KEZ46458.1 - 0.15 12.1 4.2 7.8 6.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc29 PF17082.5 KEZ46458.1 - 0.15 11.9 5.4 0.15 11.9 0.6 2.6 2 1 0 2 2 2 0 Spindle Pole Component 29 APG6_N PF17675.1 KEZ46458.1 - 0.15 12.5 15.5 0.24 11.9 1.0 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KEZ46458.1 - 0.27 11.3 17.7 0.12 12.5 2.5 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 KEZ46458.1 - 0.37 9.7 7.2 0.3 10.0 0.2 2.6 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF2203 PF09969.9 KEZ46458.1 - 0.5 11.1 10.2 0.96 10.2 0.3 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Laminin_II PF06009.12 KEZ46458.1 - 0.55 10.2 10.3 0.62 10.1 0.4 3.7 2 1 1 4 4 4 0 Laminin Domain II DUF2408 PF10303.9 KEZ46458.1 - 0.55 10.8 6.8 0.93 10.1 2.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.10 KEZ46458.1 - 0.81 9.9 6.2 18 5.5 0.1 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 KEZ46458.1 - 0.95 7.9 9.2 0.15 10.5 3.4 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family FlxA PF14282.6 KEZ46458.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.3 2 1 0 3 3 3 0 FlxA-like protein Spc7 PF08317.11 KEZ46458.1 - 2.1 7.2 14.3 1 8.2 2.3 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein XhlA PF10779.9 KEZ46458.1 - 2.4 8.4 15.7 2.9 8.2 0.4 4.5 4 1 1 5 5 5 0 Haemolysin XhlA MIP-T3_C PF17749.1 KEZ46458.1 - 2.9 7.8 13.0 2.4 8.1 0.6 3.2 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region GrpE PF01025.19 KEZ46458.1 - 3.2 7.4 11.4 0.2 11.3 1.8 3.0 2 1 0 3 3 3 0 GrpE DivIC PF04977.15 KEZ46458.1 - 3.3 7.6 17.5 0.52 10.1 0.7 3.5 3 1 1 4 4 4 0 Septum formation initiator Prefoldin_2 PF01920.20 KEZ46458.1 - 3.4 7.7 13.1 3.3 7.7 1.1 3.5 3 1 0 3 3 3 0 Prefoldin subunit Golgin_A5 PF09787.9 KEZ46458.1 - 4 6.8 15.7 1.2 8.5 1.7 3.0 2 1 1 3 3 3 0 Golgin subfamily A member 5 Ribosomal_S28e PF01200.18 KEZ46459.1 - 4.3e-16 58.6 1.0 6.8e-16 58.0 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S28e ThiS PF02597.20 KEZ46459.1 - 2.3e-08 34.5 0.0 3.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 ThiS family Complex1_LYR PF05347.15 KEZ46460.1 - 3e-16 59.2 0.5 3.8e-16 58.9 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KEZ46460.1 - 0.0015 19.3 0.1 0.0021 18.8 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KEZ46460.1 - 0.04 14.5 0.3 0.09 13.4 0.2 1.6 1 1 0 1 1 1 0 Complex1_LYR-like 23S_rRNA_IVP PF05635.11 KEZ46460.1 - 0.051 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein DUF2102 PF09875.9 KEZ46460.1 - 0.12 12.1 0.3 0.19 11.4 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) Glyco_transf_34 PF05637.12 KEZ46462.1 - 1.9e-65 220.9 0.4 2.5e-65 220.6 0.4 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family FMO-like PF00743.19 KEZ46463.1 - 7.3e-11 41.2 0.0 5.3e-09 35.0 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ46463.1 - 9.4e-10 38.6 0.0 2.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KEZ46463.1 - 7e-07 28.8 0.0 0.00088 18.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KEZ46463.1 - 0.00022 21.3 0.0 0.7 9.9 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KEZ46463.1 - 0.00074 18.9 0.0 0.027 13.7 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KEZ46463.1 - 0.016 14.5 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 KEZ46463.1 - 0.029 13.5 0.0 4.5 6.3 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) AP2 PF00847.20 KEZ46463.1 - 5.2 7.4 6.7 0.33 11.2 1.3 1.8 2 0 0 2 2 2 0 AP2 domain Methyltransf_16 PF10294.9 KEZ46464.1 - 0.0056 16.4 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase GPI-anchored PF10342.9 KEZ46465.1 - 3.3e-16 59.8 0.1 3.3e-16 59.8 0.1 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RAP1 PF07218.11 KEZ46465.1 - 0.045 12.0 13.6 0.05 11.9 13.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ORC6 PF05460.13 KEZ46465.1 - 0.69 9.1 5.3 0.8 8.9 5.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sporozoite_P67 PF05642.11 KEZ46465.1 - 1.3 7.0 13.9 1.3 7.0 13.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 KEZ46465.1 - 9.2 4.7 8.5 11 4.4 8.5 1.1 1 0 0 1 1 1 0 Macoilin family Fer2_3 PF13085.6 KEZ46466.1 - 5.4e-32 110.0 0.0 8.5e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.6 KEZ46466.1 - 9.8e-09 35.2 3.2 9.8e-09 35.2 3.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 KEZ46466.1 - 2.7e-08 34.2 6.5 2.7e-08 34.2 6.5 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KEZ46466.1 - 8.7e-08 32.5 8.4 8.7e-08 32.5 8.4 2.4 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 KEZ46466.1 - 0.0017 18.3 0.4 0.0017 18.3 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Peptidase_C6 PF00851.18 KEZ46466.1 - 0.055 12.4 0.1 0.077 11.9 0.1 1.1 1 0 0 1 1 1 0 Helper component proteinase Fer4_9 PF13187.6 KEZ46466.1 - 0.33 11.2 12.6 4 7.7 10.9 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 KEZ46466.1 - 2.8 8.6 17.4 0.84 10.3 10.9 2.9 2 2 1 3 3 3 0 4Fe-4S dicluster domain Epimerase PF01370.21 KEZ46467.1 - 1.3e-17 64.0 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KEZ46467.1 - 1.4e-07 31.0 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KEZ46467.1 - 0.002 17.2 0.0 0.0044 16.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KEZ46467.1 - 0.033 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F_actin_cap_B PF01115.17 KEZ46468.1 - 1.6e-103 345.5 0.0 1.8e-103 345.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit BAH PF01426.18 KEZ46469.1 - 0.00099 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 KEZ46469.1 - 0.0079 16.1 3.7 0.019 14.8 3.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.11 KEZ46469.1 - 0.033 14.5 0.3 0.072 13.4 0.3 1.5 1 0 0 1 1 1 0 RING-like domain IglC PF11550.8 KEZ46469.1 - 0.035 13.6 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Intracellular growth locus C protein FANCL_C PF11793.8 KEZ46469.1 - 0.061 13.5 1.1 0.15 12.3 1.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 KEZ46469.1 - 0.1 12.8 0.3 0.42 10.9 0.1 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain ATG22 PF11700.8 KEZ46470.1 - 1.4e-191 637.3 6.8 1.6e-191 637.1 6.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Cg6151-P PF10233.9 KEZ46471.1 - 1.6e-37 128.3 14.8 1.8e-37 128.1 14.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.13 KEZ46471.1 - 3.1 7.3 6.4 9.1 5.8 6.4 1.9 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF1430 PF07242.11 KEZ46471.1 - 3.3 8.0 9.2 1.7 8.9 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Aim21 PF11489.8 KEZ46472.1 - 8.4e-86 289.5 100.2 2.3e-49 169.0 52.4 3.5 2 1 1 3 3 3 2 Altered inheritance of mitochondria protein 21 Dna2 PF08696.11 KEZ46473.1 - 1.4e-69 234.0 0.0 3e-69 232.9 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KEZ46473.1 - 1.3e-52 178.4 0.0 2e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ46473.1 - 2.7e-32 112.6 2.8 1.5e-16 61.0 0.0 2.8 2 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KEZ46473.1 - 2.1e-14 53.7 0.0 8.3e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KEZ46473.1 - 3.4e-12 46.9 0.2 1.4e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.17 KEZ46473.1 - 5.6e-09 36.3 0.0 2.2e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KEZ46473.1 - 1.5e-06 28.2 0.6 0.7 9.6 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KEZ46473.1 - 0.00055 19.8 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KEZ46473.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 KEZ46473.1 - 0.0031 17.2 0.2 0.0073 16.0 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 KEZ46473.1 - 0.0034 16.6 0.0 0.11 11.7 0.1 2.2 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.6 KEZ46473.1 - 0.0046 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 KEZ46473.1 - 0.017 15.2 0.2 0.046 13.8 0.2 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 KEZ46473.1 - 0.017 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PEPCK_ATP PF01293.20 KEZ46473.1 - 0.037 12.7 0.0 0.062 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF87 PF01935.17 KEZ46473.1 - 0.07 13.2 0.1 0.29 11.2 0.2 2.0 2 0 0 2 2 1 0 Helicase HerA, central domain cobW PF02492.19 KEZ46473.1 - 0.083 12.5 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 KEZ46473.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ArAE_2_N PF10337.9 KEZ46474.1 - 4.4e-09 35.9 11.3 6.7e-07 28.7 0.7 3.4 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KEZ46474.1 - 0.0082 16.3 15.1 0.019 15.1 15.2 1.6 1 1 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KEZ46474.1 - 0.025 14.4 0.0 0.21 11.4 0.0 2.3 1 1 0 1 1 1 0 Aromatic acid exporter family member 2 ESSS PF10183.9 KEZ46475.1 - 2.3e-12 47.0 0.0 2.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.19 KEZ46476.1 - 1.9e-36 126.0 0.0 2.6e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV CVNH PF08881.10 KEZ46477.1 - 8.9e-13 48.8 0.0 1.1e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Calsarcin PF05556.11 KEZ46477.1 - 0.25 10.8 0.0 0.34 10.4 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Pkinase PF00069.25 KEZ46478.1 - 1.7e-16 60.4 0.0 6.1e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46478.1 - 1.8e-09 37.3 0.0 1.1e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1515 PF07439.11 KEZ46478.1 - 0.038 14.0 0.0 13 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DCB PF16213.5 KEZ46478.1 - 0.085 12.5 0.6 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 KRTAP PF11759.8 KEZ46478.1 - 0.93 10.1 4.9 1.1 9.9 3.5 1.8 2 0 0 2 2 2 0 Keratin-associated matrix Tyrosinase PF00264.20 KEZ46479.1 - 2e-30 106.7 0.0 4.6e-30 105.6 0.0 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KEZ46479.1 - 0.16 12.7 0.0 0.8 10.4 0.0 2.0 1 1 0 1 1 1 0 Tyosinase C-terminal domain Fungal_trans PF04082.18 KEZ46480.1 - 1.5e-22 79.9 0.0 3.3e-22 78.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46480.1 - 0.00041 20.4 6.8 0.00071 19.7 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-primase PF09329.11 KEZ46481.1 - 1.1e-18 66.8 1.7 1.9e-18 66.0 1.7 1.4 1 0 0 1 1 1 1 Primase zinc finger DASH_Duo1 PF08651.10 KEZ46482.1 - 2.9e-31 107.0 0.1 4.1e-31 106.6 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.14 KEZ46482.1 - 0.011 15.0 1.7 0.011 15.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FliN_N PF16973.5 KEZ46482.1 - 9.5 6.1 7.5 8 6.4 0.9 2.4 2 0 0 2 2 2 0 Flagellar motor switch protein FliN N-terminal TTL PF03133.15 KEZ46484.1 - 2.9e-54 184.2 0.0 5e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 KEZ46484.1 - 1.6e-51 174.9 0.0 2.4e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 KEZ46484.1 - 0.00042 19.7 0.0 0.0024 17.1 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp Cation_ATPase_C PF00689.21 KEZ46485.1 - 9.4e-41 139.5 4.6 9.4e-41 139.5 4.6 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KEZ46485.1 - 2.8e-33 115.0 1.6 2.8e-33 115.0 1.6 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KEZ46485.1 - 9.3e-21 73.7 0.0 1.8e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KEZ46485.1 - 3.2e-20 73.3 0.0 9.7e-20 71.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KEZ46485.1 - 9.7e-05 22.2 0.8 0.00025 20.9 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KEZ46485.1 - 0.00024 20.7 0.0 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus RskA PF10099.9 KEZ46485.1 - 0.009 16.3 0.3 0.61 10.4 0.0 3.5 2 1 0 2 2 2 1 Anti-sigma-K factor rskA HAD PF12710.7 KEZ46485.1 - 0.037 14.4 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KEZ46485.1 - 1.3 7.8 8.6 0.041 12.7 1.9 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG SIR2 PF02146.17 KEZ46486.1 - 1.5e-56 191.1 0.0 2.4e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Apt1 PF10351.9 KEZ46486.1 - 0.022 13.7 4.9 0.032 13.1 4.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF592 PF04574.13 KEZ46486.1 - 0.045 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) FYDLN_acid PF09538.10 KEZ46486.1 - 0.27 11.9 5.1 13 6.5 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Hamartin PF04388.12 KEZ46486.1 - 0.41 9.3 4.7 0.57 8.8 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 KEZ46486.1 - 1.8 7.0 7.7 2.9 6.3 7.7 1.3 1 0 0 1 1 1 0 Macoilin family NARP1 PF12569.8 KEZ46486.1 - 6.4 5.5 5.3 9.3 5.0 5.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AC_N PF16214.5 KEZ46486.1 - 8 5.5 6.4 13 4.8 6.4 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TT_ORF2 PF02957.15 KEZ46486.1 - 8.9 7.3 8.5 1.7 9.6 3.4 2.2 2 0 0 2 2 2 0 TT viral ORF2 Spermine_synth PF01564.17 KEZ46488.1 - 8e-08 31.9 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KEZ46488.1 - 0.0024 17.7 0.0 0.0093 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46488.1 - 0.057 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.21 KEZ46488.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_12 PF08242.12 KEZ46488.1 - 0.12 13.2 0.0 0.27 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46488.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RCC1 PF00415.18 KEZ46490.1 - 5.1e-50 167.9 17.9 7.5e-09 36.1 0.4 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KEZ46490.1 - 6.2e-34 115.1 32.7 2e-10 40.2 1.3 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KEZ46490.1 - 0.084 13.3 0.1 14 6.1 0.0 3.2 4 0 0 4 4 4 0 SUKH-3 immunity protein NAD_binding_2 PF03446.15 KEZ46491.1 - 1.8e-30 106.2 0.1 3.1e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KEZ46491.1 - 4.1e-11 43.3 0.3 1.6e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KEZ46491.1 - 9.3e-11 41.9 0.0 2.5e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 KEZ46491.1 - 2.3e-09 37.6 0.1 5.1e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sacchrp_dh_NADP PF03435.18 KEZ46491.1 - 0.00044 20.5 0.1 0.00089 19.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KEZ46491.1 - 0.00047 20.4 0.1 0.0015 18.8 0.1 1.8 1 1 0 1 1 1 1 TrkA-N domain Phyto-Amp PF15438.6 KEZ46491.1 - 0.0085 16.0 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Antigenic membrane protein of phytoplasma GFO_IDH_MocA PF01408.22 KEZ46491.1 - 0.037 14.8 0.1 0.12 13.2 0.0 1.9 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ATP_synt_H PF05493.13 KEZ46492.1 - 3.7e-19 68.9 3.7 4.3e-19 68.7 3.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Fig1 PF12351.8 KEZ46492.1 - 0.47 10.4 4.3 0.51 10.2 4.3 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF5325 PF17259.2 KEZ46492.1 - 6 6.8 7.9 2.4 8.1 2.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Arv1 PF04161.13 KEZ46493.1 - 2.2e-78 263.3 0.0 2.5e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Arv1-like family Fungal_trans PF04082.18 KEZ46494.1 - 6.4e-38 130.3 0.0 9.9e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PigN PF04987.14 KEZ46495.1 - 3e-159 530.7 31.5 4.1e-159 530.3 31.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KEZ46495.1 - 4.1e-10 39.8 5.5 2.7e-08 33.8 5.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KEZ46495.1 - 8.4e-08 32.0 0.1 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KEZ46495.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Csm1 PF12539.8 KEZ46496.1 - 2e-34 118.1 0.1 3.6e-34 117.2 0.1 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TMF_DNA_bd PF12329.8 KEZ46496.1 - 1.5e-05 24.8 3.2 1.5e-05 24.8 3.2 2.7 1 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 KEZ46496.1 - 0.0009 19.4 8.7 0.0012 19.0 7.8 1.6 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 KEZ46496.1 - 0.011 15.8 6.4 0.018 15.1 6.4 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Phlebovirus_NSM PF07246.11 KEZ46496.1 - 0.012 15.0 4.8 0.017 14.5 4.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GAS PF13851.6 KEZ46496.1 - 0.013 14.9 2.6 0.013 14.9 2.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.13 KEZ46496.1 - 0.013 14.7 6.0 0.02 14.1 6.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region EzrA PF06160.12 KEZ46496.1 - 0.022 13.0 6.4 0.031 12.4 6.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CALCOCO1 PF07888.11 KEZ46496.1 - 0.023 13.6 10.0 0.034 13.0 10.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.19 KEZ46496.1 - 0.04 11.8 4.9 0.055 11.4 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 KEZ46496.1 - 0.087 11.7 9.2 0.14 11.0 9.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4472 PF14739.6 KEZ46496.1 - 0.16 12.7 7.6 2.7 8.7 1.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) Atg14 PF10186.9 KEZ46496.1 - 0.19 10.8 8.6 0.34 10.0 8.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YpjP PF14005.6 KEZ46496.1 - 0.22 11.6 0.4 0.56 10.3 0.4 1.6 1 0 0 1 1 1 0 YpjP-like protein DDE_Tnp_IS66 PF03050.14 KEZ46496.1 - 0.31 10.5 4.6 0.5 9.8 4.6 1.2 1 0 0 1 1 1 0 Transposase IS66 family CHDCT2 PF08074.11 KEZ46496.1 - 0.32 11.1 2.0 0.54 10.4 2.0 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain CENP-H PF05837.12 KEZ46496.1 - 0.34 11.3 14.8 0.41 11.1 5.4 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Muted PF14942.6 KEZ46496.1 - 0.39 11.1 7.3 0.36 11.2 0.4 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Phage_GP20 PF06810.11 KEZ46496.1 - 0.42 10.4 9.1 0.82 9.5 9.1 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 KEZ46496.1 - 0.61 10.1 10.1 1.7 8.7 10.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 KEZ46496.1 - 0.7 10.6 5.3 0.4 11.3 0.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 KEZ46496.1 - 0.77 10.2 8.7 1.4 9.3 8.7 1.4 1 0 0 1 1 1 0 Fez1 JAKMIP_CC3 PF16034.5 KEZ46496.1 - 0.77 9.7 9.5 9.1 6.2 8.3 2.0 1 1 0 1 1 1 0 JAKMIP CC3 domain Prominin PF05478.11 KEZ46496.1 - 0.8 7.6 2.1 1 7.3 2.1 1.1 1 0 0 1 1 1 0 Prominin THOC7 PF05615.13 KEZ46496.1 - 0.87 9.9 11.2 0.27 11.5 1.0 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 DUF3450 PF11932.8 KEZ46496.1 - 0.93 8.7 12.5 2.4 7.4 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 KEZ46496.1 - 0.95 9.5 10.5 1.6 8.8 9.3 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 KEZ46496.1 - 1 6.8 12.8 1.3 6.4 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MCC-bdg_PDZ PF10506.9 KEZ46496.1 - 1.1 9.3 5.7 2.4 8.3 0.5 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome BST2 PF16716.5 KEZ46496.1 - 1.2 9.7 8.5 4.7 7.9 8.4 2.0 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 ABC_tran_CTD PF16326.5 KEZ46496.1 - 2.1 8.6 8.2 0.38 11.0 1.1 2.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain FUSC PF04632.12 KEZ46496.1 - 3 6.3 5.3 4.4 5.7 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.12 KEZ46496.1 - 4.2 8.1 5.9 3.3 8.4 0.4 3.0 1 1 2 3 3 3 0 SlyX ATG16 PF08614.11 KEZ46496.1 - 4.6 7.4 19.1 0.21 11.8 13.3 1.8 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) Fmp27_WPPW PF10359.9 KEZ46496.1 - 4.6 6.0 8.4 5.4 5.7 7.6 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.12 KEZ46496.1 - 5.3 7.1 17.3 7.4 6.7 16.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 KEZ46496.1 - 6.9 5.9 14.0 7.3 5.8 12.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KEZ46496.1 - 8.1 5.6 8.9 5.4 6.2 0.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein XhlA PF10779.9 KEZ46496.1 - 9.7 6.5 7.1 1.9 8.7 0.4 2.5 2 1 0 2 2 2 0 Haemolysin XhlA AAA PF00004.29 KEZ46497.1 - 1.2e-37 129.3 0.0 1.8e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ46497.1 - 4.9e-09 35.9 0.0 1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KEZ46497.1 - 1.3e-06 28.3 0.0 3.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEZ46497.1 - 2.8e-06 27.8 0.2 0.00023 21.6 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KEZ46497.1 - 6.6e-06 26.2 0.2 4.7e-05 23.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KEZ46497.1 - 1.2e-05 25.5 0.0 3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KEZ46497.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ46497.1 - 4.8e-05 23.7 0.3 0.006 16.8 0.0 2.7 1 1 2 3 3 2 1 AAA domain TniB PF05621.11 KEZ46497.1 - 5.3e-05 22.7 0.0 0.081 12.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_25 PF13481.6 KEZ46497.1 - 8.3e-05 22.3 1.3 0.036 13.6 0.1 2.7 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 KEZ46497.1 - 0.0001 22.8 0.1 0.0013 19.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ46497.1 - 0.00026 21.2 0.0 0.00068 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KEZ46497.1 - 0.0005 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KEZ46497.1 - 0.0008 18.8 0.1 0.0021 17.5 0.1 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KEZ46497.1 - 0.0014 19.0 0.0 0.0032 17.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 KEZ46497.1 - 0.0022 17.9 0.0 0.014 15.3 0.0 2.1 1 1 1 2 2 2 1 NACHT domain Rad17 PF03215.15 KEZ46497.1 - 0.0028 17.6 0.0 0.0082 16.1 0.0 1.7 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 KEZ46497.1 - 0.0029 17.8 0.0 0.0095 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KEZ46497.1 - 0.0042 16.8 0.0 0.0099 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KEZ46497.1 - 0.0086 16.0 0.1 0.23 11.4 0.0 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KEZ46497.1 - 0.014 15.1 0.1 0.057 13.1 0.0 2.0 3 0 0 3 3 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 KEZ46497.1 - 0.023 15.1 0.4 0.094 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KEZ46497.1 - 0.028 14.9 0.0 0.052 14.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 KEZ46497.1 - 0.031 14.4 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 KEZ46497.1 - 0.037 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KEZ46497.1 - 0.042 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KEZ46497.1 - 0.043 13.1 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 KEZ46497.1 - 0.052 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KEZ46497.1 - 0.055 13.0 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region TIP49 PF06068.13 KEZ46497.1 - 0.06 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Guanylate_kin PF00625.21 KEZ46497.1 - 0.096 12.4 0.0 6.2 6.5 0.0 3.0 2 1 1 3 3 3 0 Guanylate kinase NB-ARC PF00931.22 KEZ46497.1 - 0.1 11.8 0.0 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 KEZ46497.1 - 0.1 11.9 0.0 0.56 9.5 0.0 2.0 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.11 KEZ46497.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KEZ46497.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cys_Met_Meta_PP PF01053.20 KEZ46498.1 - 1.7e-140 467.9 0.0 2e-140 467.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KEZ46498.1 - 1.3e-06 27.7 0.0 6.3e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KEZ46498.1 - 1.5e-06 27.6 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KEZ46498.1 - 8.5e-06 25.3 0.3 3e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KEZ46498.1 - 0.00048 18.8 0.1 0.0014 17.2 0.1 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KEZ46498.1 - 0.0067 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KEZ46498.1 - 0.036 13.3 0.3 0.1 11.8 0.2 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase MFS_1 PF07690.16 KEZ46499.1 - 4.9e-16 58.6 12.9 4.9e-16 58.6 12.9 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KEZ46499.1 - 9.6e-13 48.2 2.8 9.6e-13 48.2 2.8 1.8 2 0 0 2 2 2 1 Nodulin-like PGAP1 PF07819.13 KEZ46500.1 - 1.9e-93 312.4 0.0 2.6e-93 312.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KEZ46500.1 - 0.00016 22.3 0.1 0.00043 21.0 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ46500.1 - 0.0022 17.7 0.1 0.0063 16.2 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ46500.1 - 0.0036 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 KEZ46500.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KEZ46500.1 - 0.039 13.5 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KEZ46500.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 KEZ46500.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF3094 PF11293.8 KEZ46500.1 - 1.9 8.2 4.4 12 5.7 4.4 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) MutL_C PF08676.11 KEZ46501.1 - 1.7e-23 83.0 0.1 5.5e-23 81.4 0.1 1.9 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KEZ46501.1 - 5.9e-18 64.7 0.0 1.5e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KEZ46501.1 - 3.5e-10 39.9 0.1 8.2e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KEZ46501.1 - 3.2e-06 27.6 0.0 9.5e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.14 KEZ46503.1 - 2.1e-07 30.4 0.0 0.00014 21.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KEZ46503.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ETF PF01012.21 KEZ46504.1 - 2.3e-43 148.2 3.4 3.4e-43 147.6 3.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KEZ46504.1 - 5.4e-34 116.1 0.4 1.2e-33 115.0 0.4 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.17 KEZ46505.1 - 1.7e-32 111.6 0.1 3.6e-32 110.6 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KEZ46505.1 - 6.1e-30 103.0 6.0 1.3e-29 102.0 6.0 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KEZ46505.1 - 1.4e-11 44.3 0.1 3.7e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KEZ46505.1 - 1.2e-07 31.9 0.1 2.6e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KEZ46505.1 - 0.029 14.6 0.1 0.081 13.1 0.1 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KEZ46505.1 - 0.19 11.7 0.8 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 Myb DNA-binding like DUF3439 PF11921.8 KEZ46505.1 - 0.27 11.2 9.6 0.28 11.1 7.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Carn_acyltransf PF00755.20 KEZ46506.1 - 2e-201 670.7 0.0 2.2e-201 670.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.19 KEZ46507.1 - 6.3e-118 393.9 3.0 9.8e-118 393.2 3.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KEZ46507.1 - 5.8e-55 185.2 1.8 8.2e-55 184.7 1.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF2774 PF11242.8 KEZ46507.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) PfkB PF00294.24 KEZ46508.1 - 3.6e-13 49.5 0.0 4.7e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.23 KEZ46509.1 - 5.6e-98 326.5 0.2 1.1e-97 325.5 0.2 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KEZ46509.1 - 6.4e-32 110.1 0.0 1.3e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KEZ46509.1 - 9.9e-24 83.6 0.5 2.3e-23 82.4 0.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KEZ46509.1 - 4.1e-07 29.6 0.0 4.8e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KEZ46509.1 - 0.0015 18.4 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KEZ46509.1 - 0.0089 15.7 0.1 0.031 14.0 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 KEZ46509.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIIF_alpha PF05793.12 KEZ46509.1 - 0.091 11.3 7.5 0.13 10.8 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Exo70 PF03081.15 KEZ46510.1 - 4.2e-90 302.5 0.0 7.5e-90 301.7 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Enkurin PF13864.6 KEZ46510.1 - 0.13 12.7 0.2 0.65 10.5 0.1 2.3 2 0 0 2 2 2 0 Calmodulin-binding Apolipoprotein PF01442.18 KEZ46510.1 - 0.44 10.4 6.0 0.84 9.5 0.5 3.3 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain GAS PF13851.6 KEZ46510.1 - 1.4 8.3 7.5 3.1 7.1 0.2 3.2 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Syja_N PF02383.18 KEZ46511.1 - 2.3e-63 214.4 0.0 1e-60 205.7 0.0 2.4 1 1 0 1 1 1 1 SacI homology domain Tox-ODYAM1 PF15642.6 KEZ46511.1 - 0.06 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus PolyA_pol PF01743.20 KEZ46512.1 - 1.1e-27 96.9 0.0 2.8e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KEZ46512.1 - 5.9e-07 29.2 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 KEZ46512.1 - 0.0014 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Suf PF05843.14 KEZ46513.1 - 1.7e-11 44.7 6.0 0.049 13.6 0.0 6.3 4 1 2 7 7 7 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KEZ46513.1 - 8e-11 41.8 23.7 4.8 8.3 0.3 12.1 11 4 2 13 13 12 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KEZ46513.1 - 7.3e-08 31.9 8.5 0.0021 17.2 0.1 6.0 2 2 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 KEZ46513.1 - 3.3e-07 29.8 2.9 0.00012 21.4 0.4 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46513.1 - 2.8e-06 27.1 4.2 0.18 12.1 0.0 6.3 6 0 0 6 6 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KEZ46513.1 - 4e-06 26.8 7.8 0.18 11.8 0.1 6.5 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KEZ46513.1 - 0.00022 21.5 4.1 7.1 7.0 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 KEZ46513.1 - 0.01 15.6 0.2 0.48 10.1 0.0 2.8 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 KEZ46513.1 - 0.021 15.2 2.2 5 7.7 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TetR_C_11 PF16859.5 KEZ46513.1 - 0.026 14.8 0.4 0.18 12.1 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_2 PF07719.17 KEZ46513.1 - 0.94 9.8 17.0 49 4.4 0.1 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat HAT PF02184.16 KEZ46513.1 - 2.3 8.2 15.1 2.8 8.0 0.0 6.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat ATP-synt_D PF01813.17 KEZ46514.1 - 1.1e-24 87.4 3.6 2.6e-19 69.8 0.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit D T6PP_N PF18572.1 KEZ46514.1 - 0.073 12.9 0.5 0.16 11.9 0.5 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain RRM_1 PF00076.22 KEZ46515.1 - 8.4e-25 86.4 0.5 2.2e-11 43.4 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ46515.1 - 3.2e-05 23.5 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1027 PF06265.11 KEZ46515.1 - 0.13 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) PHM7_cyt PF14703.6 KEZ46515.1 - 0.44 10.8 3.7 18 5.5 0.1 3.2 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Sec7 PF01369.20 KEZ46516.1 - 4.7e-66 222.0 0.0 7.5e-66 221.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KEZ46516.1 - 6.3e-16 58.7 0.9 4.1e-15 56.0 0.0 2.8 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KEZ46516.1 - 0.24 11.3 0.6 8.8 6.3 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Anp1 PF03452.14 KEZ46517.1 - 8e-112 372.9 1.1 1.7e-111 371.9 0.0 1.9 2 0 0 2 2 2 1 Anp1 RNA_pol_Rpb8 PF03870.15 KEZ46519.1 - 1.1e-44 152.0 0.0 1.3e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KEZ46519.1 - 2.3e-06 27.7 0.3 0.046 13.8 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G GDA1_CD39 PF01150.17 KEZ46520.1 - 7.8e-105 351.0 0.0 1e-104 350.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RNase_H2_suC PF08615.11 KEZ46521.1 - 0.057 13.6 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LVIVD PF08309.11 KEZ46522.1 - 6.5e-09 35.0 0.0 0.15 11.4 0.0 4.8 4 0 0 4 4 4 4 LVIVD repeat DLH PF01738.18 KEZ46523.1 - 1.5e-16 60.6 0.1 2.9e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family SGL PF08450.12 KEZ46524.1 - 2.2e-32 112.6 0.1 3.1e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KEZ46524.1 - 0.0018 18.2 1.0 4 7.6 0.0 3.7 4 0 0 4 4 4 2 NHL repeat Str_synth PF03088.16 KEZ46524.1 - 0.0062 16.6 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase Reg_prop PF07494.11 KEZ46524.1 - 0.15 12.4 0.7 68 4.2 0.0 4.3 6 0 0 6 6 6 0 Two component regulator propeller Methyltransf_23 PF13489.6 KEZ46526.1 - 3.5e-20 72.5 0.0 4.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46526.1 - 1.9e-12 47.7 0.0 5.2e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46526.1 - 5.3e-10 39.8 0.0 1.4e-09 38.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46526.1 - 3e-09 37.5 0.0 2.5e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46526.1 - 5e-09 36.1 0.0 4.5e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KEZ46526.1 - 4.7e-06 26.2 0.0 1.8e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KEZ46526.1 - 0.00035 20.7 0.0 0.0011 19.2 0.0 1.6 1 1 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ46526.1 - 0.00037 20.1 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KEZ46526.1 - 0.00041 19.8 0.0 0.0039 16.6 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 KEZ46526.1 - 0.033 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0146 PF03686.13 KEZ46526.1 - 0.043 13.7 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) CMAS PF02353.20 KEZ46526.1 - 0.06 12.6 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DAPG_hydrolase PF18089.1 KEZ46526.1 - 0.076 12.5 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain Methyltransf_9 PF08003.11 KEZ46526.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF938 PF06080.12 KEZ46526.1 - 0.21 11.3 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cu-oxidase_2 PF07731.14 KEZ46527.1 - 3e-43 146.8 9.4 1.6e-39 134.8 3.7 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KEZ46527.1 - 7.2e-43 145.4 1.9 5.3e-38 129.7 0.1 3.2 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KEZ46527.1 - 9.1e-40 136.4 0.7 1.5e-34 119.4 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KEZ46527.1 - 0.00026 21.0 0.0 10 6.3 0.0 3.8 3 1 0 4 4 4 2 Cupredoxin-like domain DUF5060 PF16586.5 KEZ46527.1 - 0.033 14.6 0.4 0.81 10.1 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5060) FTR1 PF03239.14 KEZ46528.1 - 1.3e-58 198.6 7.1 5.4e-32 111.2 0.2 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family S_4TM PF18159.1 KEZ46528.1 - 0.18 11.1 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF1218 PF06749.12 KEZ46528.1 - 0.61 10.6 5.9 0.51 10.9 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Hydrophobin PF01185.18 KEZ46529.1 - 1.4e-07 32.0 8.6 2.4e-07 31.3 8.6 1.4 1 0 0 1 1 1 1 Fungal hydrophobin Pam17 PF08566.10 KEZ46529.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 GMC_oxred_N PF00732.19 KEZ46530.1 - 8.4e-61 205.9 0.0 1.1e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ46530.1 - 1.3e-31 110.1 0.0 2.4e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KEZ46530.1 - 0.0025 18.0 0.2 0.0099 16.1 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KEZ46530.1 - 0.012 14.7 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KEZ46530.1 - 0.013 14.7 0.1 0.027 13.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KEZ46530.1 - 0.12 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Transp_cyt_pur PF02133.15 KEZ46531.1 - 5.4e-147 490.1 35.2 6.3e-147 489.9 35.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.19 KEZ46532.1 - 6.8e-50 168.9 0.0 1.3e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEZ46532.1 - 3.1e-15 56.0 0.0 3.8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEZ46532.1 - 0.00012 22.3 0.0 0.00047 20.3 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KEZ46532.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KEZ46532.1 - 0.042 13.9 0.1 0.14 12.2 0.0 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FTR1 PF03239.14 KEZ46533.1 - 8.5e-48 163.1 4.2 9.6e-48 162.9 4.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Cu-oxidase_3 PF07732.15 KEZ46534.1 - 7.5e-45 151.8 8.5 8.6e-42 141.9 1.7 4.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEZ46534.1 - 5e-43 146.1 8.9 2.8e-39 134.0 0.1 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KEZ46534.1 - 1.9e-38 132.1 0.1 1.4e-34 119.5 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KEZ46534.1 - 0.0012 18.9 0.0 6.3 7.0 0.0 3.9 4 0 0 4 4 4 1 Cupredoxin-like domain TauD PF02668.16 KEZ46535.1 - 4.5e-52 177.5 0.2 5.5e-52 177.2 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ketoacyl-synt PF00109.26 KEZ46536.1 - 1.4e-70 237.8 0.0 3e-70 236.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KEZ46536.1 - 6.4e-63 211.9 0.8 6.4e-63 211.9 0.8 2.1 3 0 0 3 3 1 1 KR domain Acyl_transf_1 PF00698.21 KEZ46536.1 - 1.9e-56 191.9 0.0 3.4e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KEZ46536.1 - 3.3e-47 161.2 0.0 6.2e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KEZ46536.1 - 6.4e-40 135.9 0.3 3.3e-39 133.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KEZ46536.1 - 6.9e-18 65.1 0.0 2.8e-17 63.2 0.0 2.1 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KEZ46536.1 - 3.2e-17 62.6 0.8 3.2e-17 62.6 0.8 2.7 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 KEZ46536.1 - 1.1e-16 62.1 0.0 4e-16 60.3 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KEZ46536.1 - 1.5e-14 54.1 0.9 4.6e-13 49.3 0.2 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KEZ46536.1 - 1.5e-13 50.9 0.2 1.5e-13 50.9 0.2 2.8 4 0 0 4 4 3 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KEZ46536.1 - 7.3e-08 32.3 0.1 2.2e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KEZ46536.1 - 4.5e-06 26.9 0.2 1.3e-05 25.4 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sacchrp_dh_NADP PF03435.18 KEZ46536.1 - 1.5e-05 25.3 0.1 8.2e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KEZ46536.1 - 1.7e-05 24.0 0.6 2.9e-05 23.2 0.6 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KEZ46536.1 - 4.8e-05 22.9 0.2 9.5e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KEZ46536.1 - 0.00017 20.8 0.1 0.00028 20.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 KEZ46536.1 - 0.00032 20.2 0.0 0.0012 18.3 0.0 2.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.21 KEZ46536.1 - 0.0038 16.7 0.1 0.0074 15.8 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 KEZ46536.1 - 0.021 14.3 0.5 1.5 8.2 0.1 2.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Shikimate_DH PF01488.20 KEZ46536.1 - 0.034 14.2 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KEZ46536.1 - 0.038 14.5 0.2 5.7 7.6 0.0 3.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Hemagglutinin PF00509.18 KEZ46536.1 - 0.21 9.9 0.0 0.53 8.6 0.0 1.5 2 0 0 2 2 2 0 Haemagglutinin An_peroxidase PF03098.15 KEZ46537.1 - 3.5e-32 111.7 0.0 1.6e-23 83.1 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KEZ46537.1 - 1.4e-13 50.4 0.0 2.3e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 DUF2235 PF09994.9 KEZ46538.1 - 1.2e-88 297.3 0.2 1.7e-88 296.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Transferase PF02458.15 KEZ46539.1 - 3.1e-13 49.2 0.0 3e-11 42.6 0.0 2.5 2 1 0 2 2 2 2 Transferase family SBF PF01758.16 KEZ46540.1 - 9e-26 90.8 1.4 9e-26 90.8 1.4 2.1 2 1 1 3 3 3 1 Sodium Bile acid symporter family MFS_1 PF07690.16 KEZ46542.1 - 5.2e-25 88.1 21.6 6.7e-25 87.8 21.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.28 KEZ46543.1 - 2.6e-78 264.2 0.0 3.4e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KEZ46543.1 - 1.1e-06 28.7 0.0 0.022 14.6 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Aminotran_1_2 PF00155.21 KEZ46544.1 - 1.2e-11 44.4 0.0 2.6e-10 40.0 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aldo_ket_red PF00248.21 KEZ46545.1 - 5.5e-32 111.1 0.0 8.7e-29 100.6 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family HpcH_HpaI PF03328.14 KEZ46546.1 - 1.1e-27 96.7 0.0 7.3e-23 80.9 0.0 2.1 1 1 1 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.18 KEZ46547.1 - 8.7e-16 57.7 0.0 1.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KEZ46549.1 - 1.1e-16 60.7 8.6 1.2e-16 60.6 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ46549.1 - 3.2e-05 23.0 14.2 3.5e-05 22.9 14.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KEZ46550.1 - 0.055 12.4 0.1 0.062 12.2 0.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.16 KEZ46551.1 - 2.1e-16 59.8 8.5 2.8e-16 59.4 8.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CFEM PF05730.11 KEZ46553.1 - 9.7e-16 57.6 13.6 1.7e-15 56.8 13.6 1.4 1 0 0 1 1 1 1 CFEM domain p450 PF00067.22 KEZ46554.1 - 2.3e-65 221.2 0.0 3.1e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KEZ46554.1 - 0.079 12.7 0.1 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split Sugar_tr PF00083.24 KEZ46555.1 - 2.4e-94 316.8 17.9 2.7e-94 316.6 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ46555.1 - 3.4e-32 111.7 39.7 1.4e-29 103.2 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1011 PF06237.12 KEZ46555.1 - 0.027 14.8 2.1 0.027 14.8 2.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1011) Phage_holin_3_2 PF04550.12 KEZ46555.1 - 0.11 13.0 2.5 1.2 9.7 2.2 2.6 2 0 0 2 2 2 0 Phage holin family 2 TRI12 PF06609.13 KEZ46555.1 - 0.17 10.2 8.2 0.022 13.2 1.2 2.4 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.23 KEZ46556.1 - 1.4e-20 73.4 0.6 2.6e-20 72.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ46556.1 - 1.1e-12 47.8 0.1 6.2e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like Phage_tail_APC PF16778.5 KEZ46556.1 - 0.044 13.7 1.4 0.069 13.0 0.2 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone protein MFS_1 PF07690.16 KEZ46557.1 - 3.2e-23 82.2 20.7 4.4e-23 81.8 20.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KEZ46557.1 - 4.9e-05 23.1 4.1 0.00012 21.8 4.1 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Aminotran_1_2 PF00155.21 KEZ46558.1 - 2.8e-41 141.9 0.0 3.5e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KEZ46558.1 - 0.028 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Ribonuc_L-PSP PF01042.21 KEZ46559.1 - 2.3e-25 88.9 0.0 2.9e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Beta-lactamase PF00144.24 KEZ46560.1 - 1.8e-25 89.9 0.0 3.2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 KEZ46561.1 - 4.8e-40 137.6 34.8 4.8e-40 137.6 34.8 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily YbhQ PF11076.8 KEZ46561.1 - 1 9.3 5.1 5 7.1 3.1 2.4 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Glyco_hydro_61 PF03443.14 KEZ46562.1 - 4.8e-62 209.5 0.0 5.6e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4337 PF14235.6 KEZ46562.1 - 0.13 12.4 0.2 0.18 11.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) p450 PF00067.22 KEZ46564.1 - 3.1e-37 128.4 0.0 5.1e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KEZ46565.1 - 4.6e-16 58.7 10.0 5.1e-16 58.5 10.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KEZ46566.1 - 1.3e-17 63.6 28.0 1.8e-09 37.5 9.4 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ46566.1 - 0.00013 21.1 0.0 0.00029 20.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cellulase PF00150.18 KEZ46567.1 - 2.1e-49 168.5 10.4 3.5e-49 167.7 10.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NMO PF03060.15 KEZ46567.1 - 2.8e-32 112.4 1.2 1.9e-25 89.9 1.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase CBM_1 PF00734.18 KEZ46567.1 - 4.6e-14 52.1 13.0 4.6e-14 52.1 13.0 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain IMPDH PF00478.25 KEZ46567.1 - 1.6e-10 40.6 0.4 1.8e-09 37.0 0.4 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KEZ46567.1 - 6.5e-07 28.7 3.4 1e-06 28.0 3.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KEZ46567.1 - 3.6e-06 26.4 0.5 6.2e-06 25.6 0.5 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Toxin_7 PF05980.12 KEZ46567.1 - 0.099 12.9 3.0 0.19 12.0 3.0 1.5 1 0 0 1 1 1 0 Toxin 7 DHO_dh PF01180.21 KEZ46567.1 - 0.18 11.0 0.5 0.33 10.1 0.5 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase RTA1 PF04479.13 KEZ46568.1 - 0.011 15.3 1.9 0.011 15.3 1.9 2.3 2 1 0 2 2 2 0 RTA1 like protein FAD_binding_4 PF01565.23 KEZ46569.1 - 6.3e-23 81.1 2.3 8.5e-23 80.6 1.3 1.8 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 KEZ46569.1 - 6.6e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.19 KEZ46571.1 - 2.9e-80 270.2 0.0 3.7e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KEZ46571.1 - 0.0066 15.7 0.1 0.021 14.0 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ46571.1 - 0.06 12.4 0.2 0.099 11.7 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 KEZ46571.1 - 0.11 12.0 1.0 1.8 8.0 0.3 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Glyoxalase PF00903.25 KEZ46572.1 - 3.4e-08 33.7 7.6 5.4e-07 29.8 1.3 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KEZ46572.1 - 0.013 15.8 0.0 2.2 8.6 0.0 3.2 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GFO_IDH_MocA PF01408.22 KEZ46573.1 - 4.7e-14 53.3 0.0 7.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Alkyl_sulf_dimr PF14863.6 KEZ46574.1 - 1.1e-53 181.4 0.0 1.7e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 KEZ46574.1 - 1.6e-22 80.5 0.0 5.8e-22 78.7 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 KEZ46574.1 - 5e-18 65.6 0.1 1.1e-17 64.5 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 KEZ46574.1 - 0.00048 19.7 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SCP2 PF02036.17 KEZ46574.1 - 0.086 13.3 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family MFS_1 PF07690.16 KEZ46575.1 - 4.1e-39 134.5 49.4 2.8e-36 125.2 33.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily HSP70 PF00012.20 KEZ46577.1 - 0.0052 15.0 0.0 0.18 10.0 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.20 KEZ46577.1 - 0.053 13.0 0.0 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Sugar_tr PF00083.24 KEZ46578.1 - 3.6e-90 303.0 20.5 4.5e-90 302.7 20.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KEZ46578.1 - 1.2e-08 34.3 45.5 9e-07 28.1 33.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.11 KEZ46578.1 - 0.0031 16.7 0.2 0.0063 15.8 0.2 1.4 1 0 0 1 1 1 1 UAA transporter family NmrA PF05368.13 KEZ46579.1 - 1.3e-13 51.1 0.1 5.3e-13 49.1 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KEZ46579.1 - 2.9e-11 43.6 0.0 1.4e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ46579.1 - 1.4e-05 24.6 0.3 0.00018 21.1 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KEZ46579.1 - 0.038 13.9 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 KEZ46579.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RAI16-like PF10257.9 KEZ46581.1 - 7.9e-74 248.7 3.7 1.1e-73 248.2 3.7 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Carb_bind PF10645.9 KEZ46582.1 - 1.4e-20 73.2 10.9 3.6e-20 71.9 10.9 1.7 1 0 0 1 1 1 1 Carbohydrate binding Zn_clus PF00172.18 KEZ46585.1 - 7.5e-11 42.0 10.0 1.2e-10 41.3 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KEZ46585.1 - 1.6e-07 30.6 3.0 2.6e-07 30.0 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.13 KEZ46586.1 - 0.016 15.2 10.9 0.024 14.6 10.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 KEZ46586.1 - 0.017 14.3 12.1 0.019 14.1 12.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ndc1_Nup PF09531.10 KEZ46586.1 - 0.019 13.7 9.7 0.023 13.4 9.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FlaG PF03646.15 KEZ46586.1 - 0.054 13.7 0.3 0.054 13.7 0.3 1.5 2 0 0 2 2 2 0 FlaG protein Suf PF05843.14 KEZ46586.1 - 0.093 12.7 7.0 0.11 12.4 7.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Baculo_PP31 PF05311.11 KEZ46586.1 - 0.26 10.8 5.6 0.4 10.1 5.6 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Roughex PF06020.11 KEZ46586.1 - 2.6 7.0 5.2 0.2 10.7 0.3 1.6 2 0 0 2 2 2 0 Drosophila roughex protein Amidase PF01425.21 KEZ46587.1 - 8.2e-72 242.6 0.0 2.9e-69 234.2 0.0 2.0 1 1 0 1 1 1 1 Amidase LIDHydrolase PF10230.9 KEZ46588.1 - 4.9e-57 193.5 0.0 5.7e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KEZ46588.1 - 3.8e-05 24.4 0.1 5.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KEZ46588.1 - 0.021 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ46588.1 - 0.021 14.1 0.2 0.48 9.6 0.1 2.7 2 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF89 PF01937.19 KEZ46589.1 - 1.1e-135 452.2 0.0 1.2e-135 452.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Exo_endo_phos PF03372.23 KEZ46590.1 - 7.1e-15 55.1 0.2 8.2e-14 51.7 0.2 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KEZ46590.1 - 5.5e-09 35.7 6.1 8.6e-07 28.6 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KEZ46590.1 - 5.8e-09 36.1 3.7 0.00015 22.1 0.0 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KEZ46590.1 - 0.067 13.8 6.0 13 6.8 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Complex1_LYR PF05347.15 KEZ46591.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) ADIP PF11559.8 KEZ46593.1 - 0.0022 18.1 1.7 0.0039 17.3 1.7 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 KEZ46593.1 - 0.027 15.0 2.6 0.044 14.3 2.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CLP_protease PF00574.23 KEZ46594.1 - 1e-65 221.0 0.0 1.3e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Clp protease AAA_12 PF13087.6 KEZ46595.1 - 6.8e-09 35.6 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zn_clus PF00172.18 KEZ46596.1 - 0.00027 21.0 9.7 0.00027 21.0 9.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrcA PF01628.21 KEZ46596.1 - 0.0081 16.1 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 HrcA protein C terminal domain zf-Di19 PF05605.12 KEZ46596.1 - 0.027 14.8 0.1 0.027 14.8 0.1 3.3 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF948 PF06103.11 KEZ46596.1 - 0.14 12.4 0.0 0.46 10.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) zinc_ribbon_4 PF13717.6 KEZ46596.1 - 0.23 11.4 4.4 9.6 6.2 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_3rep PF18868.1 KEZ46596.1 - 1.2 9.9 7.0 5.6 7.7 0.8 3.2 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Glyco_hydro_6 PF01341.17 KEZ46597.1 - 3.6e-99 332.4 0.0 4.6e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KEZ46597.1 - 1.4e-13 50.5 14.8 3.3e-13 49.4 14.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Yeast-kill-tox PF09207.11 KEZ46597.1 - 0.074 13.7 7.0 0.096 13.3 4.5 2.3 2 0 0 2 2 2 0 Yeast killer toxin MGC-24 PF05283.11 KEZ46597.1 - 4.4 7.7 8.9 17 5.9 8.9 1.9 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RRG8 PF17068.5 KEZ46598.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial BAR PF03114.18 KEZ46599.1 - 1.2e-50 172.4 7.0 1.9e-50 171.8 7.0 1.3 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KEZ46599.1 - 1e-06 28.1 3.3 1.3e-06 27.8 3.3 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Uds1 PF15456.6 KEZ46599.1 - 1.1 9.4 13.5 0.39 10.9 7.2 2.7 2 1 1 3 3 3 0 Up-regulated During Septation LRR_6 PF13516.6 KEZ46600.1 - 1.2e-16 59.3 19.8 0.65 10.2 0.0 12.4 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.7 KEZ46600.1 - 1.4e-13 50.8 6.4 0.35 11.4 0.0 6.9 5 1 1 7 7 7 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KEZ46600.1 - 6.2e-13 48.4 1.6 1e-12 47.7 0.8 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KEZ46600.1 - 0.00023 21.0 0.0 0.00073 19.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 KEZ46600.1 - 0.0012 18.5 0.4 3.8 7.2 0.0 4.1 3 2 1 4 4 4 2 Protein of unknown function (DUF1699) Peptidase_C37 PF05416.12 KEZ46600.1 - 0.25 9.8 0.0 0.39 9.2 0.0 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Glutaredoxin PF00462.24 KEZ46601.1 - 9e-21 73.9 0.0 1.3e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KEZ46601.1 - 0.00021 21.7 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 KEZ46601.1 - 0.0014 18.5 0.1 0.034 13.9 0.1 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain DUF836 PF05768.14 KEZ46601.1 - 0.0096 16.3 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.6 KEZ46601.1 - 0.029 14.5 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.6 KEZ46601.1 - 0.077 13.4 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 KEZ46601.1 - 0.088 13.0 0.6 1.1 9.5 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 KEZ46601.1 - 0.11 12.6 0.1 0.41 10.7 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin PF00085.20 KEZ46601.1 - 0.14 12.2 0.1 0.23 11.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin DUF5635 PF18685.1 KEZ46603.1 - 0.024 14.5 0.3 0.042 13.8 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5635) CAP59_mtransfer PF11735.8 KEZ46604.1 - 2.9e-72 243.3 0.0 3.6e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Swi5 PF07061.11 KEZ46605.1 - 3.2e-17 62.4 1.9 5.7e-17 61.6 0.0 2.2 2 1 0 2 2 2 1 Swi5 RRF PF01765.19 KEZ46605.1 - 0.024 14.6 1.4 0.028 14.4 0.2 1.6 2 0 0 2 2 2 0 Ribosome recycling factor DUF4363 PF14276.6 KEZ46605.1 - 0.15 12.2 4.2 0.34 11.1 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) SKG6 PF08693.10 KEZ46606.1 - 0.12 11.8 0.4 0.23 10.9 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4680 PF15730.5 KEZ46606.1 - 1.2 9.5 3.3 1.9 8.8 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Ribosomal_L13 PF00572.18 KEZ46607.1 - 6.4e-11 42.6 0.0 5.7e-09 36.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 BAR PF03114.18 KEZ46608.1 - 7.2e-68 228.8 5.1 9.3e-68 228.4 5.1 1.1 1 0 0 1 1 1 1 BAR domain SVIP PF15811.5 KEZ46608.1 - 0.55 10.7 4.1 0.24 11.9 0.6 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Ammonium_transp PF00909.21 KEZ46609.1 - 2.9e-121 404.9 25.6 3.3e-121 404.8 25.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tweety PF04906.13 KEZ46609.1 - 0.14 10.8 2.1 0.19 10.3 0.8 1.7 2 0 0 2 2 2 0 Tweety WSC PF01822.19 KEZ46610.1 - 8.6e-15 54.7 8.3 8.6e-15 54.7 8.3 1.8 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.11 KEZ46610.1 - 0.00013 22.2 0.2 0.00022 21.4 0.2 1.3 1 0 0 1 1 1 1 Podoplanin Shisa PF13908.6 KEZ46610.1 - 0.0003 21.1 0.8 0.00081 19.7 0.8 1.7 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Amnionless PF14828.6 KEZ46610.1 - 0.0061 15.5 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.10 KEZ46610.1 - 0.018 14.4 4.8 0.036 13.5 4.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Orf78 PF06024.12 KEZ46610.1 - 0.048 14.0 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) BatD PF13584.6 KEZ46610.1 - 0.053 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance S1FA PF04689.13 KEZ46610.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA DUF4366 PF14283.6 KEZ46610.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4690 PF15756.5 KEZ46610.1 - 0.28 11.8 8.0 0.25 11.9 5.7 2.2 2 1 0 2 2 2 0 Small Novel Rich in Cartilage VSP PF03302.13 KEZ46610.1 - 0.74 8.6 17.3 1.1 8.1 15.6 1.8 1 1 0 1 1 1 0 Giardia variant-specific surface protein Bestrophin PF01062.21 KEZ46611.1 - 4e-34 118.4 0.0 7.9e-34 117.4 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Cyclin_C_2 PF16899.5 KEZ46613.1 - 2.4e-35 121.1 0.8 3.5e-33 114.1 0.1 2.5 2 1 0 2 2 2 2 Cyclin C-terminal domain TMA7 PF09072.10 KEZ46613.1 - 0.19 12.6 0.6 0.47 11.3 0.1 1.9 2 0 0 2 2 2 0 Translation machinery associated TMA7 Promethin PF16015.5 KEZ46614.1 - 2e-33 114.5 17.1 2.4e-33 114.2 17.1 1.1 1 0 0 1 1 1 1 Promethin Glyco_hydro_10 PF00331.20 KEZ46615.1 - 4.2e-101 338.3 0.2 5.2e-101 337.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KEZ46615.1 - 9.1e-15 54.3 13.5 2.6e-14 52.9 13.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain HC2 PF07382.11 KEZ46616.1 - 9.2e-06 25.9 22.9 0.00018 21.6 7.6 2.0 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 AAA PF00004.29 KEZ46617.1 - 0.00025 21.5 0.0 0.00069 20.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Goodbye PF17109.5 KEZ46617.1 - 0.00045 20.7 0.1 0.0018 18.7 0.1 2.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KEZ46617.1 - 0.0012 18.7 1.0 0.028 14.3 0.2 2.8 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KEZ46617.1 - 0.0019 18.6 2.4 1.9 8.8 0.0 3.9 2 1 1 3 3 3 2 AAA ATPase domain Glyco_hydro_72 PF03198.14 KEZ46619.1 - 7.1e-119 396.7 1.3 9.3e-119 396.3 1.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KEZ46619.1 - 2.3e-24 85.9 5.3 6.3e-24 84.5 5.3 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KEZ46619.1 - 0.00018 20.7 0.0 0.0017 17.5 0.0 2.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain OPT PF03169.15 KEZ46620.1 - 3.2e-69 234.2 38.2 4e-52 177.7 27.0 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Radical_SAM_C PF16199.5 KEZ46622.1 - 5.7e-32 109.6 0.0 1.1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KEZ46622.1 - 1e-16 61.8 0.1 4.2e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KEZ46622.1 - 1.3e-07 31.8 0.1 2.4e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KEZ46622.1 - 1.3e-05 25.2 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KEZ46622.1 - 0.091 13.2 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 KEZ46623.1 - 2.6e-27 95.3 2.0 5.1e-27 94.4 0.3 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KEZ46623.1 - 6.3e-24 84.5 0.2 1e-23 83.8 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KEZ46623.1 - 2.5e-09 37.0 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KEZ46623.1 - 0.00031 21.2 0.0 0.00082 19.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain UQ_con PF00179.26 KEZ46624.1 - 4.1e-40 136.7 0.0 5.3e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ46624.1 - 2.9e-05 23.8 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.10 KEZ46624.1 - 6e-05 22.8 0.1 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UEV PF05743.13 KEZ46624.1 - 0.0029 17.4 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 KEZ46624.1 - 0.033 14.5 0.0 0.072 13.4 0.0 1.6 2 0 0 2 2 2 0 RWD domain Ntox47 PF15540.6 KEZ46624.1 - 0.068 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 47 DUF1421 PF07223.11 KEZ46624.1 - 0.12 12.2 0.5 0.26 11.2 0.4 1.6 1 1 0 1 1 1 0 UBA-like domain (DUF1421) AAA PF00004.29 KEZ46625.1 - 4.3e-41 140.4 0.0 7.4e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEZ46625.1 - 1.1e-11 44.5 0.2 2.4e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KEZ46625.1 - 1.9e-10 40.3 0.5 3.5e-10 39.5 0.5 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KEZ46625.1 - 1.7e-06 28.2 0.0 3.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEZ46625.1 - 4.7e-06 26.9 0.2 0.0054 17.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KEZ46625.1 - 1.2e-05 24.7 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KEZ46625.1 - 8.8e-05 22.5 0.1 0.0003 20.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEZ46625.1 - 0.00022 21.0 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KEZ46625.1 - 0.00025 21.4 0.3 0.0029 18.0 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KEZ46625.1 - 0.00071 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KEZ46625.1 - 0.0013 18.4 0.7 0.0068 16.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 KEZ46625.1 - 0.0028 17.9 0.6 0.0092 16.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ46625.1 - 0.0097 16.1 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KEZ46625.1 - 0.015 15.2 0.1 0.61 10.0 0.1 2.4 1 1 1 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 KEZ46625.1 - 0.018 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 KEZ46625.1 - 0.019 14.5 1.2 0.5 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KEZ46625.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KEZ46625.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KEZ46625.1 - 0.025 13.8 0.1 0.062 12.5 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 KEZ46625.1 - 0.031 13.6 0.2 0.52 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 KEZ46625.1 - 0.052 13.9 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KEZ46625.1 - 0.058 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KEZ46625.1 - 0.065 12.5 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KEZ46625.1 - 0.099 12.2 1.3 0.54 9.8 0.4 2.4 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KEZ46625.1 - 0.11 12.3 0.3 0.28 10.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KEZ46625.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KEZ46625.1 - 0.2 11.2 0.1 0.51 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Lipase_3 PF01764.25 KEZ46626.1 - 1.3e-19 70.5 0.0 2.2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KEZ46626.1 - 0.047 12.9 0.0 0.086 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 KEZ46626.1 - 0.051 13.1 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 KEZ46626.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein YihI PF04220.12 KEZ46626.1 - 0.55 9.9 2.4 1.1 8.9 2.4 1.5 1 0 0 1 1 1 0 Der GTPase activator (YihI) IHABP4_N PF16174.5 KEZ46626.1 - 1.3 9.6 0.0 1.3 9.6 0.0 2.8 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal CFEM PF05730.11 KEZ46627.1 - 2.8e-06 27.3 11.0 4.1e-06 26.8 11.0 1.3 1 0 0 1 1 1 1 CFEM domain betaPIX_CC PF16523.5 KEZ46628.1 - 0.00076 19.3 3.7 0.0013 18.5 3.7 1.4 1 0 0 1 1 1 1 betaPIX coiled coil zf-C2H2 PF00096.26 KEZ46628.1 - 0.0029 18.0 0.9 0.0064 16.9 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ46628.1 - 0.041 14.7 0.5 0.11 13.5 0.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KEZ46628.1 - 0.081 13.3 0.4 0.16 12.4 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Ytp1 PF10355.9 KEZ46630.1 - 1.4e-67 227.8 18.3 1.4e-67 227.8 18.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KEZ46630.1 - 7.1e-23 80.4 3.7 7.1e-23 80.4 3.7 3.1 5 0 0 5 5 5 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KEZ46630.1 - 6.4e-05 23.1 3.4 6.4e-05 23.1 3.4 3.0 4 0 0 4 4 4 1 Eukaryotic cytochrome b561 FAD_binding_4 PF01565.23 KEZ46631.1 - 5.1e-23 81.3 2.0 9.4e-23 80.5 1.4 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KEZ46631.1 - 3.6e-13 49.4 0.1 7.6e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.9 KEZ46632.1 - 8.5e-84 281.7 0.0 1.1e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FliC PF12445.8 KEZ46632.1 - 0.21 11.9 2.2 0.17 12.2 0.5 1.7 2 0 0 2 2 2 0 Flagellin protein He_PIG PF05345.12 KEZ46632.1 - 0.41 10.9 7.1 0.11 12.6 2.2 2.8 2 1 0 2 2 2 0 Putative Ig domain Acyltransferase PF01553.21 KEZ46633.1 - 4.4e-26 91.1 0.0 6.7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KEZ46633.1 - 2.4e-13 50.0 0.0 4.4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus DUF2015 PF09435.10 KEZ46633.1 - 0.22 11.4 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) GFO_IDH_MocA PF01408.22 KEZ46634.1 - 5e-22 79.0 0.0 7.5e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KEZ46634.1 - 2.9e-13 49.9 0.0 4.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Methyltransf_23 PF13489.6 KEZ46635.1 - 9.2e-19 67.9 0.0 1.4e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46635.1 - 4.1e-08 33.8 0.0 1.2e-07 32.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46635.1 - 5.6e-07 29.5 0.0 7.4e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46635.1 - 5.7e-05 23.7 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46635.1 - 0.00042 21.0 0.0 0.0049 17.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KEZ46635.1 - 0.00048 19.5 0.0 0.0046 16.3 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 KEZ46635.1 - 0.00061 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KEZ46635.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KEZ46635.1 - 0.086 12.1 0.0 0.17 11.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KEZ46635.1 - 0.19 11.2 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Git3 PF11710.8 KEZ46636.1 - 7.1e-17 61.9 2.5 1.2e-16 61.1 2.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KEZ46636.1 - 2.4e-06 27.1 1.4 7.9e-06 25.4 1.4 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 KEZ46636.1 - 0.0022 18.0 0.1 0.0022 18.0 0.1 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 5_nucleotid_C PF02872.18 KEZ46637.1 - 8.4e-37 126.8 0.0 1.8e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KEZ46637.1 - 8.6e-12 46.0 0.4 1.9e-11 44.8 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 KEZ46637.1 - 0.00029 20.2 0.0 0.0071 15.7 0.0 2.6 3 0 0 3 3 3 1 YmdB-like protein NAD_binding_10 PF13460.6 KEZ46639.1 - 1.4e-32 113.1 0.0 2.7e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KEZ46639.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KEZ46639.1 - 0.011 14.9 0.0 0.063 12.4 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein ADH_zinc_N PF00107.26 KEZ46639.1 - 0.014 15.4 0.0 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF2569 PF10754.9 KEZ46639.1 - 0.084 13.3 3.4 0.16 12.4 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) HPP PF04982.13 KEZ46640.1 - 6.3e-38 129.7 7.6 6.3e-38 129.7 7.6 1.6 2 0 0 2 2 2 1 HPP family Ycf66_N PF07444.11 KEZ46640.1 - 0.079 13.1 0.4 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Ycf66 protein N-terminus DUF3377 PF11857.8 KEZ46640.1 - 0.15 12.0 0.6 0.37 10.8 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cu-oxidase_3 PF07732.15 KEZ46641.1 - 4.3e-43 146.1 3.7 1.8e-40 137.7 0.4 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KEZ46641.1 - 2.3e-41 140.8 7.5 5.3e-37 126.6 0.4 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KEZ46641.1 - 6e-37 127.2 0.1 2.8e-31 108.8 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KEZ46641.1 - 0.0052 16.9 0.0 18 5.5 0.0 3.9 4 0 0 4 4 4 1 Cupredoxin-like domain TauD PF02668.16 KEZ46642.1 - 1.8e-23 83.7 0.0 2.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KEZ46642.1 - 5.2e-05 22.5 0.0 7.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 CsiD Zn_clus PF00172.18 KEZ46643.1 - 0.24 11.5 9.9 0.5 10.5 9.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4716 PF15837.5 KEZ46644.1 - 6 7.0 8.0 1.8 8.7 1.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4716) Adap_comp_sub PF00928.21 KEZ46646.1 - 3.1e-84 282.5 0.0 3.9e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KEZ46646.1 - 3.2e-05 23.9 0.2 5.9e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KEZ46646.1 - 0.026 14.0 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain RIBIOP_C PF04950.12 KEZ46646.1 - 0.031 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal ABC_tran PF00005.27 KEZ46647.1 - 2.8e-47 160.7 0.0 5.8e-22 78.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KEZ46647.1 - 4.6e-22 77.8 1.3 4.6e-22 77.8 1.3 2.8 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KEZ46647.1 - 4.3e-19 69.4 0.2 0.00017 21.5 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KEZ46647.1 - 1e-10 41.4 0.1 0.34 10.3 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KEZ46647.1 - 9.7e-09 34.9 0.0 0.0022 17.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KEZ46647.1 - 2e-07 31.7 5.2 0.022 15.3 0.0 3.6 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 KEZ46647.1 - 1.4e-06 28.3 0.1 0.0027 17.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KEZ46647.1 - 1.5e-06 28.2 0.0 0.048 13.4 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 KEZ46647.1 - 6.7e-06 26.6 0.0 0.016 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KEZ46647.1 - 8.1e-06 25.9 0.0 0.028 14.5 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KEZ46647.1 - 8.5e-06 26.1 0.0 0.09 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KEZ46647.1 - 8.6e-05 22.5 0.2 0.29 11.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 KEZ46647.1 - 0.00012 22.6 0.0 0.25 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KEZ46647.1 - 0.00023 21.5 0.0 0.09 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KEZ46647.1 - 0.00044 20.3 0.1 1.1 9.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KEZ46647.1 - 0.00056 20.3 1.3 3 8.3 0.0 3.5 3 0 0 3 3 3 2 RNA helicase AAA PF00004.29 KEZ46647.1 - 0.00056 20.3 0.4 1.4 9.4 0.0 3.2 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 KEZ46647.1 - 0.0011 18.6 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KEZ46647.1 - 0.0014 18.8 0.0 1.1 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KEZ46647.1 - 0.0018 18.0 0.4 1.5 8.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KEZ46647.1 - 0.0024 17.1 0.6 3.5 6.8 0.0 3.3 3 1 1 4 4 4 1 NB-ARC domain Roc PF08477.13 KEZ46647.1 - 0.0028 17.8 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF2813 PF11398.8 KEZ46647.1 - 0.0043 16.4 0.3 0.66 9.2 0.0 2.5 3 0 0 3 3 2 1 Protein of unknown function (DUF2813) AAA_14 PF13173.6 KEZ46647.1 - 0.0092 16.0 0.0 4.6 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KEZ46647.1 - 0.011 15.3 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KEZ46647.1 - 0.013 15.1 0.0 1 8.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain MCM PF00493.23 KEZ46647.1 - 0.018 14.1 0.1 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Dynamin_N PF00350.23 KEZ46647.1 - 0.029 14.4 0.4 16 5.5 0.0 3.6 3 1 0 4 4 4 0 Dynamin family AAA_17 PF13207.6 KEZ46647.1 - 0.042 14.3 0.0 7.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KEZ46647.1 - 0.045 13.5 0.7 4 7.1 0.1 3.4 3 1 0 3 3 3 0 AAA domain DUF815 PF05673.13 KEZ46647.1 - 0.066 12.4 0.1 3.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KEZ46647.1 - 0.068 13.1 0.1 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.9 KEZ46647.1 - 0.12 11.2 0.1 25 3.5 0.0 3.2 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DAP3 PF10236.9 KEZ46647.1 - 0.12 11.5 1.0 8.4 5.5 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 KEZ46647.1 - 0.13 12.2 0.3 16 5.3 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KEZ46647.1 - 0.13 12.1 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain FeoB_N PF02421.18 KEZ46647.1 - 0.18 11.3 0.3 16 5.0 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B SNF2_N PF00176.23 KEZ46648.1 - 1.8e-65 221.0 1.1 4.5e-65 219.7 1.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KEZ46648.1 - 9.1e-47 158.8 21.0 9.1e-47 158.8 21.0 5.7 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 KEZ46648.1 - 3.5e-20 72.4 0.0 8.7e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ46648.1 - 1.7e-07 31.4 0.0 1.7e-07 31.4 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KEZ46648.1 - 0.028 13.6 0.0 0.028 13.6 0.0 3.0 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 VID27_PH PF17747.1 KEZ46648.1 - 0.17 12.1 2.3 17 5.7 0.2 2.8 3 0 0 3 3 3 0 VID27 PH-like domain Fe_hyd_lg_C PF02906.14 KEZ46648.1 - 0.7 9.5 4.0 0.59 9.8 1.9 2.0 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Zip PF02535.22 KEZ46649.1 - 1.2e-29 103.7 34.0 9.9e-13 48.0 5.6 3.3 2 1 1 3 3 3 3 ZIP Zinc transporter DNA_primase_lrg PF04104.14 KEZ46650.1 - 1.6e-84 283.5 0.0 4e-84 282.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Ank_2 PF12796.7 KEZ46651.1 - 0.00073 20.1 0.0 1.5 9.4 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF568 PF04526.13 KEZ46651.1 - 0.061 14.0 0.0 5.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF568) Pkinase PF00069.25 KEZ46652.1 - 2.7e-43 148.3 0.0 1.8e-42 145.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46652.1 - 1.6e-26 93.1 0.0 3.4e-26 92.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ46652.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KEZ46652.1 - 0.67 8.8 1.5 2.7 6.8 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Clr5 PF14420.6 KEZ46653.1 - 4.8e-23 81.1 0.5 3e-22 78.6 0.3 2.3 2 0 0 2 2 2 1 Clr5 domain DUF3433 PF11915.8 KEZ46654.1 - 3.3e-08 33.9 2.1 3.3e-08 33.9 2.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) CrgA PF06781.12 KEZ46654.1 - 0.56 10.3 1.7 9.3 6.4 0.0 3.5 3 0 0 3 3 3 0 Cell division protein CrgA GST_N PF02798.20 KEZ46655.1 - 5.2e-14 52.3 0.0 9.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KEZ46655.1 - 2.1e-13 50.5 0.0 3.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KEZ46655.1 - 3.1e-12 46.6 0.1 9.5e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KEZ46655.1 - 9.4e-12 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KEZ46655.1 - 4.1e-11 43.0 0.0 8.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KEZ46655.1 - 1.6e-08 34.5 0.1 3.3e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PI_PP_I PF18363.1 KEZ46656.1 - 0.05 13.8 2.7 2.1 8.6 0.0 3.5 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain BLOC1_2 PF10046.9 KEZ46656.1 - 0.17 12.2 12.8 0.29 11.4 3.6 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF641 PF04859.12 KEZ46656.1 - 0.35 11.2 14.4 4.4 7.7 6.8 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Aida_N PF08910.10 KEZ46656.1 - 0.47 10.9 3.5 0.65 10.4 1.4 2.4 1 1 1 2 2 2 0 Aida N-terminus Syntaxin-6_N PF09177.11 KEZ46656.1 - 0.55 10.8 11.5 3.8 8.1 5.0 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATG16 PF08614.11 KEZ46656.1 - 1.2 9.4 23.2 0.33 11.2 3.7 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KEZ46656.1 - 2 8.4 9.5 2.1 8.4 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KELK PF15796.5 KEZ46656.1 - 2.7 8.5 22.5 0.68 10.4 10.6 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NYD-SP28 PF14772.6 KEZ46656.1 - 4.3 7.5 20.5 0.035 14.2 6.6 3.5 1 1 2 3 3 3 0 Sperm tail KASH_CCD PF14662.6 KEZ46656.1 - 4.6 7.0 23.7 1.2 8.9 6.1 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Phage_GP20 PF06810.11 KEZ46656.1 - 4.7 7.0 19.5 0.13 12.0 9.3 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 Fez1 PF06818.15 KEZ46656.1 - 8.2 6.8 23.4 20 5.5 4.7 2.8 1 1 1 2 2 2 0 Fez1 COG2 PF06148.11 KEZ46656.1 - 8.3 6.5 11.0 0.71 10.0 0.7 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SF1-HH PF16275.5 KEZ46657.1 - 1.2e-43 148.0 1.2 2.7e-43 146.9 1.2 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KEZ46657.1 - 5.9e-11 41.9 11.1 1.4e-05 25.0 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KEZ46657.1 - 1.9e-08 34.0 0.2 3.6e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 KEZ46657.1 - 7.1e-07 29.1 3.5 0.0006 19.7 1.1 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KEZ46657.1 - 0.00021 21.0 5.3 0.059 13.1 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 KEZ46657.1 - 0.0019 18.0 8.4 0.38 10.6 0.7 2.8 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 KEZ46657.1 - 0.015 15.1 0.5 0.015 15.1 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle Peptidase_M28 PF04389.17 KEZ46658.1 - 8.9e-33 113.7 0.0 1.4e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Med11 PF10280.9 KEZ46659.1 - 1.1e-45 155.4 0.7 1.3e-45 155.2 0.7 1.0 1 0 0 1 1 1 1 Mediator complex protein Prominin PF05478.11 KEZ46659.1 - 0.041 11.9 0.3 0.05 11.6 0.3 1.0 1 0 0 1 1 1 0 Prominin Cytochrom_B562 PF07361.11 KEZ46659.1 - 0.067 13.9 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b562 DHC_N1 PF08385.12 KEZ46659.1 - 0.14 10.8 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 WD40 PF00400.32 KEZ46660.1 - 2.3e-40 135.8 26.5 1.4e-07 32.1 2.2 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KEZ46660.1 - 1.8e-36 125.2 0.1 2.6e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KEZ46660.1 - 1.4e-10 41.3 0.8 0.042 14.2 0.0 5.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KEZ46660.1 - 9e-05 22.3 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KEZ46660.1 - 0.001 19.0 0.1 0.013 15.3 0.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KEZ46660.1 - 0.0039 15.9 0.5 1.1 7.9 0.1 3.1 1 1 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KEZ46660.1 - 0.03 13.3 0.1 18 4.1 0.0 3.5 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KEZ46660.1 - 0.046 12.5 0.0 1.9 7.1 0.0 2.6 2 1 0 2 2 2 0 Nup133 N terminal like RAB3GAP2_N PF14655.6 KEZ46660.1 - 0.051 12.8 0.0 8.8 5.5 0.0 2.8 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Vps5 PF09325.10 KEZ46661.1 - 4.4e-88 294.8 6.9 4.4e-88 294.8 6.9 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KEZ46661.1 - 9.5e-26 90.0 0.5 3.3e-25 88.3 0.1 2.0 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KEZ46661.1 - 0.0036 17.0 6.1 0.014 15.1 1.8 2.5 1 1 1 2 2 2 1 BAR domain of APPL family DUF713 PF05218.14 KEZ46661.1 - 0.019 14.7 2.5 0.036 13.8 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF713) BAR_3_WASP_bdg PF10456.9 KEZ46661.1 - 0.022 14.2 0.7 0.13 11.7 0.7 2.1 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein BAR PF03114.18 KEZ46661.1 - 0.23 11.0 10.7 0.36 10.4 8.8 2.2 2 1 0 2 2 2 0 BAR domain Flavin_Reduct PF01613.18 KEZ46662.1 - 4.6e-29 101.5 0.0 1.2e-28 100.1 0.0 1.7 1 1 0 1 1 1 1 Flavin reductase like domain Kinesin PF00225.23 KEZ46663.1 - 3.9e-104 348.2 0.1 7.4e-104 347.3 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ46663.1 - 2.7e-55 186.4 0.6 1.7e-54 183.8 0.0 2.6 3 0 0 3 3 3 1 Microtubule binding WEMBL PF05701.11 KEZ46663.1 - 1.7e-07 30.3 25.6 1.9e-07 30.2 24.2 1.7 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Lzipper-MIP1 PF14389.6 KEZ46663.1 - 0.0079 16.5 0.8 0.0079 16.5 0.8 3.1 3 0 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.11 KEZ46663.1 - 0.023 13.6 27.5 0.073 11.9 3.5 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Filament PF00038.21 KEZ46663.1 - 0.032 13.8 33.6 0.77 9.3 33.6 2.8 1 1 0 1 1 1 0 Intermediate filament protein Phage_antitermQ PF06530.12 KEZ46663.1 - 0.068 13.1 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Phage antitermination protein Q SHE3 PF17078.5 KEZ46663.1 - 0.069 12.9 21.6 1 9.0 7.4 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 AAA_16 PF13191.6 KEZ46663.1 - 0.072 13.5 0.0 0.072 13.5 0.0 2.5 2 1 0 2 2 1 0 AAA ATPase domain DUF1664 PF07889.12 KEZ46663.1 - 0.098 12.7 15.0 0.34 11.0 3.5 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc42p PF11544.8 KEZ46663.1 - 0.17 11.9 5.9 0.1 12.6 0.8 3.0 2 0 0 2 2 2 0 Spindle pole body component Spc42p AAA_22 PF13401.6 KEZ46663.1 - 0.47 10.7 2.8 1 9.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain FlaC_arch PF05377.11 KEZ46663.1 - 0.65 10.4 11.2 5.5 7.5 0.0 5.3 5 2 0 6 6 5 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KEZ46663.1 - 1.2 9.2 6.6 1.3 9.1 1.7 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 KEZ46663.1 - 1.8 8.8 33.6 48 4.1 25.9 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 KEZ46663.1 - 2.8 7.5 21.8 0.039 13.5 2.9 2.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4618 PF15397.6 KEZ46663.1 - 3.2 7.1 21.3 9.3 5.6 13.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 KEZ46663.1 - 7.5 5.8 24.2 2.2e+02 1.0 24.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 KEZ46663.1 - 9.2 6.3 32.5 2.4 8.2 0.1 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_12 PF13424.6 KEZ46664.1 - 9.6e-10 38.6 5.8 1.3e-05 25.4 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ46664.1 - 1.1e-08 34.6 0.7 0.0088 15.9 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KEZ46664.1 - 0.00022 21.9 2.6 0.00022 21.9 2.6 3.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KEZ46664.1 - 0.0021 18.4 0.0 0.013 15.9 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KEZ46664.1 - 0.013 15.6 0.0 0.075 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF676 PF05057.14 KEZ46664.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Metallophos PF00149.28 KEZ46665.1 - 1.8e-17 64.5 0.1 3.1e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KEZ46665.1 - 8.9e-08 32.5 0.0 4.3e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.27 KEZ46666.1 - 6.8e-15 54.4 0.0 1.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KEZ46666.1 - 0.00028 20.6 0.4 0.00028 20.6 0.4 2.7 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 KEZ46666.1 - 0.0064 16.2 0.1 0.015 15.0 0.1 1.7 1 1 0 1 1 1 1 HeH/LEM domain FANC_SAP PF18081.1 KEZ46666.1 - 0.063 13.4 0.3 0.18 12.0 0.3 1.8 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain p450 PF00067.22 KEZ46667.1 - 2.5e-28 99.1 0.0 3.2e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSP90 PF00183.18 KEZ46669.1 - 7e-223 741.2 32.5 8.5e-223 740.9 32.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KEZ46669.1 - 1.1e-14 54.9 0.1 2.1e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KEZ46669.1 - 3.9e-10 39.7 0.1 3.9e-10 39.7 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KEZ46669.1 - 0.026 14.5 3.9 0.18 11.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.9 KEZ46669.1 - 0.056 13.5 0.2 0.23 11.5 0.2 2.0 1 0 0 1 1 1 0 Tumour suppressor protein DUF2052 PF09747.9 KEZ46669.1 - 0.87 9.7 17.4 2.7 8.1 11.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Acyltransferase PF01553.21 KEZ46670.1 - 0.029 14.0 0.0 0.1 12.2 0.0 1.8 1 1 0 1 1 1 0 Acyltransferase ILVD_EDD PF00920.21 KEZ46671.1 - 2.5e-212 706.1 0.6 3e-212 705.8 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KEZ46671.1 - 0.0063 16.7 0.0 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain DOG1 PF14144.6 KEZ46673.1 - 0.004 17.3 0.0 0.0081 16.4 0.0 1.4 1 0 0 1 1 1 1 Seed dormancy control Metallophos PF00149.28 KEZ46674.1 - 6e-07 30.2 0.0 8.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3726 PF12525.8 KEZ46674.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) MBOAT PF03062.19 KEZ46675.1 - 4.7e-42 144.6 19.6 2.4e-41 142.3 9.6 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DUF3440 PF11922.8 KEZ46675.1 - 0.67 9.6 3.3 7.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Sacchrp_dh_C PF16653.5 KEZ46676.1 - 4.7e-96 322.0 0.0 9.3e-96 321.0 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KEZ46676.1 - 1.7e-26 93.0 0.5 3e-26 92.2 0.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KEZ46676.1 - 2.4e-06 27.7 0.2 6.1e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KEZ46676.1 - 3.5e-05 23.8 0.1 7.1e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 KEZ46676.1 - 0.0002 20.9 0.7 0.00069 19.2 0.1 2.1 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 KEZ46676.1 - 0.0021 18.5 0.8 0.0047 17.4 0.2 1.9 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_3 PF03447.16 KEZ46676.1 - 0.0024 18.5 0.3 0.0055 17.4 0.3 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KEZ46676.1 - 0.0086 16.9 0.1 0.021 15.7 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AlaDh_PNT_C PF01262.21 KEZ46676.1 - 0.0098 15.2 0.2 0.017 14.5 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SieB PF14163.6 KEZ46676.1 - 0.041 13.4 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B Glyco_transf_8 PF01501.20 KEZ46677.1 - 1.4e-25 90.4 0.1 1.5e-24 86.9 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KEZ46677.1 - 0.019 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 KEZ46677.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Mannosyltransferase putative zf-rbx1 PF12678.7 KEZ46678.1 - 1.5e-09 38.0 4.0 3e-09 37.0 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KEZ46678.1 - 3.9e-09 36.7 5.5 7.8e-09 35.7 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KEZ46678.1 - 4.7e-06 26.4 3.0 9.1e-06 25.5 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KEZ46678.1 - 1.7e-05 24.7 2.9 3.5e-05 23.7 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KEZ46678.1 - 7e-05 22.7 1.6 0.00019 21.4 1.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KEZ46678.1 - 0.00026 20.8 7.1 0.004 17.0 7.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KEZ46678.1 - 0.00027 20.5 0.4 0.00056 19.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KEZ46678.1 - 0.0006 19.6 2.9 0.0006 19.6 2.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KEZ46678.1 - 0.0019 18.0 2.2 0.0051 16.6 2.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KEZ46678.1 - 0.017 15.2 2.9 0.043 13.9 2.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KEZ46678.1 - 0.097 12.4 2.6 0.55 10.0 2.6 2.1 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 KEZ46678.1 - 0.12 12.6 0.9 0.26 11.5 0.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Radial_spoke PF04712.12 KEZ46678.1 - 1.2 8.0 14.2 0.92 8.4 11.0 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein NOA36 PF06524.12 KEZ46678.1 - 2.4 7.4 8.8 5 6.4 8.8 1.4 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 KEZ46678.1 - 4.8 7.1 11.3 0.25 11.2 3.8 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 KEZ46678.1 - 8.5 5.9 16.7 0.15 11.6 9.7 1.6 2 0 0 2 2 1 0 PPP4R2 CMD PF02627.20 KEZ46679.1 - 0.0048 16.9 0.0 0.37 10.9 0.0 2.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Allexi_40kDa PF05549.11 KEZ46679.1 - 0.0081 15.7 0.5 0.012 15.1 0.5 1.4 1 0 0 1 1 1 1 Allexivirus 40kDa protein NPV_P10 PF05531.12 KEZ46679.1 - 0.034 14.6 0.5 1.3 9.5 0.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 KEZ46679.1 - 0.036 13.6 6.4 0.069 12.7 6.4 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain SesA PF17107.5 KEZ46679.1 - 0.039 14.2 0.1 0.091 13.0 0.1 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Plasmid_RAQPRD PF09686.10 KEZ46679.1 - 0.051 13.8 0.4 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) FlaC_arch PF05377.11 KEZ46679.1 - 0.052 14.0 0.3 0.27 11.7 0.2 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) MitMem_reg PF13012.6 KEZ46679.1 - 0.072 13.5 0.6 7.1 7.1 0.0 2.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Gp58 PF07902.11 KEZ46679.1 - 0.091 11.0 2.1 0.12 10.6 2.1 1.1 1 0 0 1 1 1 0 gp58-like protein COG2 PF06148.11 KEZ46679.1 - 0.13 12.4 0.4 0.5 10.5 0.3 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3005 PF11448.8 KEZ46679.1 - 0.14 12.2 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) Baculo_PEP_C PF04513.12 KEZ46679.1 - 0.17 12.0 5.4 0.46 10.5 5.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C2H2 PF00096.26 KEZ46680.1 - 2.8e-05 24.3 17.9 0.35 11.4 0.8 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type DNA_ligase_IV PF11411.8 KEZ46680.1 - 0.063 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 DNA ligase IV zf-TAZ PF02135.16 KEZ46680.1 - 0.47 10.9 3.7 0.47 10.9 1.4 2.0 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_4 PF13894.6 KEZ46680.1 - 1.8 9.6 19.5 1.3 10.0 0.6 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KEZ46680.1 - 5.2 7.7 16.6 0.48 11.0 0.6 4.4 4 1 0 4 4 4 0 Zinc-finger double domain Methyltransf_16 PF10294.9 KEZ46681.1 - 1.1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KEZ46681.1 - 0.0031 16.9 0.1 0.0043 16.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KEZ46681.1 - 0.077 13.7 0.1 0.42 11.3 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Vps39_2 PF10367.9 KEZ46682.1 - 3.3e-06 27.5 0.0 1.1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KEZ46682.1 - 0.0014 18.9 0.0 0.019 15.3 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 KEZ46683.1 - 9e-97 323.3 0.0 9e-97 323.3 0.0 3.6 2 1 1 3 3 3 1 CASP C terminal APG6_N PF17675.1 KEZ46683.1 - 0.0048 17.4 66.9 0.026 15.1 5.4 5.9 3 1 3 6 6 6 3 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 KEZ46683.1 - 0.0085 16.5 3.5 0.0085 16.5 3.5 6.3 5 1 2 7 7 7 2 Centrosome microtubule-binding domain of Cep57 bZIP_2 PF07716.15 KEZ46683.1 - 0.02 15.0 4.8 0.02 15.0 4.8 8.7 7 2 1 8 8 8 0 Basic region leucine zipper LMBR1 PF04791.16 KEZ46683.1 - 0.035 13.0 0.0 0.035 13.0 0.0 3.1 2 1 0 2 2 1 0 LMBR1-like membrane protein TPR_MLP1_2 PF07926.12 KEZ46683.1 - 0.1 12.7 74.3 0.19 11.8 2.4 7.2 5 2 2 7 7 7 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 KEZ46683.1 - 0.16 11.2 0.1 0.16 11.2 0.1 5.0 4 1 1 5 5 5 0 HAP1 N-terminal conserved region SKA1 PF07160.12 KEZ46683.1 - 0.21 11.4 32.3 0.94 9.3 10.7 4.3 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 GAS PF13851.6 KEZ46683.1 - 0.29 10.5 61.0 1.1 8.6 7.3 5.2 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding LemA PF04011.12 KEZ46683.1 - 0.77 9.6 13.8 0.085 12.7 1.1 4.0 4 1 0 4 4 4 0 LemA family SlyX PF04102.12 KEZ46683.1 - 1.3 9.7 0.0 1.3 9.7 0.0 7.0 5 1 0 7 7 7 0 SlyX MscS_porin PF12795.7 KEZ46683.1 - 1.4 8.4 58.3 0.032 13.8 2.1 5.1 3 1 0 5 5 5 0 Mechanosensitive ion channel porin domain PI3K_P85_iSH2 PF16454.5 KEZ46683.1 - 1.8 8.1 44.5 0.1 12.2 18.3 5.0 3 1 2 5 5 5 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 KEZ46683.1 - 2.5 7.4 47.9 4.5 6.5 6.5 5.0 1 1 3 5 5 4 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KEZ46683.1 - 2.7 8.1 43.6 1.4 9.0 2.5 6.0 7 0 0 7 7 7 0 TolA binding protein trimerisation CENP-H PF05837.12 KEZ46683.1 - 3.4 8.1 62.6 0.29 11.6 1.2 6.1 4 1 2 6 6 6 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 KEZ46683.1 - 3.7 7.6 36.8 1.7 8.7 0.0 6.5 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KEZ46683.1 - 6.5 7.2 59.8 4.3 7.7 24.8 4.6 2 1 2 5 5 5 0 Fez1 YabA PF06156.13 KEZ46683.1 - 6.6 7.4 38.9 5.7 7.6 0.0 6.3 4 1 0 5 5 3 0 Initiation control protein YabA PRKG1_interact PF15898.5 KEZ46683.1 - 9 7.3 54.5 2.6 9.0 2.3 5.3 5 1 0 5 5 5 0 cGMP-dependent protein kinase interacting domain DUF3455 PF11937.8 KEZ46684.1 - 1.8e-41 142.2 0.0 3e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KEZ46684.1 - 0.0085 16.2 1.3 0.033 14.3 1.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2990) tRNA-synt_1b PF00579.25 KEZ46686.1 - 1.7e-25 90.0 0.0 2.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF4125 PF13526.6 KEZ46686.1 - 0.064 12.9 0.9 0.14 11.7 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) DUF2989 PF11207.8 KEZ46686.1 - 0.065 13.0 1.0 0.1 12.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) DUF3716 PF12511.8 KEZ46687.1 - 1.2e-05 25.3 0.3 1.8e-05 24.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SPRY PF00622.28 KEZ46688.1 - 2.7e-17 63.0 0.0 4.7e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Zn_clus PF00172.18 KEZ46689.1 - 4.3e-08 33.2 10.9 6.6e-08 32.5 10.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KEZ46689.1 - 2.5e-07 29.8 0.4 4.1e-07 29.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.6 KEZ46690.1 - 6.7e-30 103.1 9.7 3.2e-14 53.1 0.0 10.1 9 1 1 10 10 10 5 HEAT-like repeat HEAT PF02985.22 KEZ46690.1 - 1.6e-21 74.5 12.9 9.8e-06 25.4 0.0 9.0 9 0 0 9 9 8 5 HEAT repeat HEAT_2 PF13646.6 KEZ46690.1 - 3.6e-18 65.7 1.2 1.5e-06 28.5 0.0 7.1 5 2 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 KEZ46690.1 - 6.3e-09 36.1 0.1 0.0023 18.0 0.0 4.8 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KEZ46690.1 - 1.1e-07 31.6 0.2 3e-06 27.0 0.1 3.2 2 1 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KEZ46690.1 - 1.2e-06 29.0 0.1 0.043 14.4 0.0 5.7 4 2 3 7 7 7 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 KEZ46690.1 - 2.9e-06 27.1 1.1 0.47 10.6 0.0 5.8 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 KEZ46690.1 - 1.1e-05 24.8 0.8 0.26 10.4 0.0 4.6 4 1 0 5 5 5 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KEZ46690.1 - 2.5e-05 23.0 0.0 0.021 13.4 0.0 2.5 2 0 0 2 2 2 2 Adaptin N terminal region RTP1_C1 PF10363.9 KEZ46690.1 - 0.00026 21.1 0.2 0.006 16.7 0.0 3.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 KEZ46690.1 - 0.014 16.0 0.7 26 5.8 0.0 4.9 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat TAF6_C PF07571.13 KEZ46690.1 - 0.016 15.5 0.0 12 6.3 0.0 3.7 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain BP28CT PF08146.12 KEZ46690.1 - 0.04 13.8 0.0 1.7 8.5 0.0 3.3 4 0 0 4 4 3 0 BP28CT (NUC211) domain IFRD PF05004.13 KEZ46690.1 - 0.043 12.9 0.2 6.8 5.7 0.0 3.5 2 2 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Telomere_reg-2 PF10193.9 KEZ46690.1 - 0.048 14.1 1.2 11 6.5 0.0 4.2 3 1 1 4 4 4 0 Telomere length regulation protein HipN PF18253.1 KEZ46690.1 - 0.19 11.5 0.2 43 3.9 0.0 3.5 3 0 0 3 3 3 0 Hsp70-interacting protein N N-terminal domain PAC4 PF16093.5 KEZ46691.1 - 3.4e-14 52.8 0.1 6.8e-14 51.8 0.1 1.5 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Sua5_yciO_yrdC PF01300.18 KEZ46691.1 - 0.047 13.2 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Telomere recombination N2227 PF07942.12 KEZ46692.1 - 2.1e-96 322.3 0.0 2.7e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KEZ46692.1 - 3.6e-06 26.9 0.0 7.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46692.1 - 0.0062 17.2 0.0 0.19 12.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46692.1 - 0.0063 17.2 0.0 0.059 14.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46692.1 - 0.066 13.0 0.0 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain PIN_10 PF18478.1 KEZ46692.1 - 0.11 12.7 0.0 0.99 9.7 0.0 2.4 2 0 0 2 2 2 0 PIN like domain adh_short_C2 PF13561.6 KEZ46693.1 - 7.3e-49 166.4 1.2 9.6e-49 166.0 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KEZ46693.1 - 2.8e-43 147.7 1.2 4.3e-43 147.1 0.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KEZ46693.1 - 4.8e-14 52.7 0.7 7.3e-14 52.1 0.7 1.2 1 0 0 1 1 1 1 KR domain malic PF00390.19 KEZ46693.1 - 0.081 12.7 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Epimerase PF01370.21 KEZ46693.1 - 0.1 12.1 0.4 0.53 9.7 0.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SRP-alpha_N PF04086.13 KEZ46694.1 - 3 7.7 25.6 4.2 7.2 25.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 KEZ46694.1 - 5.4 5.8 12.5 7.3 5.3 12.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain p450 PF00067.22 KEZ46695.1 - 8.1e-42 143.5 0.1 1.2e-41 143.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Nitroreductase PF00881.24 KEZ46696.1 - 3.4e-15 56.5 0.0 4.1e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Pkinase PF00069.25 KEZ46697.1 - 2.9e-29 102.3 0.0 2e-28 99.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46697.1 - 1.4e-07 31.0 0.2 8.3e-05 22.0 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase HTH_31 PF13560.6 KEZ46697.1 - 0.074 13.4 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PS_Dcarbxylase PF02666.15 KEZ46699.1 - 4.6e-75 251.6 0.0 1.1e-74 250.3 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2407 PF10302.9 KEZ46700.1 - 1.4e-05 25.5 0.1 4.9e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KEZ46700.1 - 0.00025 20.7 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 KEZ46700.1 - 0.1 12.9 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Blt1 N-terminal domain Peptidase_C12 PF01088.21 KEZ46701.1 - 3.2e-69 232.9 0.0 4e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KEZ46701.1 - 4.7e-10 39.2 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases PET122 PF05476.11 KEZ46701.1 - 0.096 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 PET122 PQ-loop PF04193.14 KEZ46702.1 - 9.5e-26 89.3 1.6 8.3e-18 63.9 0.2 2.8 2 0 0 2 2 2 2 PQ loop repeat Peptidase_U4 PF03419.13 KEZ46702.1 - 0.0003 20.2 2.4 0.00031 20.1 1.4 1.5 1 1 0 1 1 1 1 Sporulation factor SpoIIGA LapA_dom PF06305.11 KEZ46702.1 - 3.8 7.4 7.9 2.6 7.9 0.1 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Dicty_CAR PF05462.11 KEZ46704.1 - 1.2e-13 50.9 5.9 1.2e-13 50.9 5.9 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KEZ46704.1 - 5.8e-10 38.9 3.9 5.8e-10 38.9 3.9 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 KEZ46704.1 - 3.5e-08 33.5 8.6 6.4e-08 32.6 8.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KEZ46704.1 - 5.5e-08 32.5 5.1 7.9e-08 31.9 5.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 KEZ46704.1 - 0.0029 16.7 10.1 0.56 9.2 10.2 2.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Glycogen_syn PF05693.13 KEZ46705.1 - 0.38 9.2 0.1 0.38 9.2 0.1 1.7 2 0 0 2 2 2 0 Glycogen synthase Macoilin PF09726.9 KEZ46705.1 - 1.1 7.8 5.3 1 7.8 5.3 1.1 1 0 0 1 1 1 0 Macoilin family SWIRM-assoc_2 PF16496.5 KEZ46705.1 - 3.8 6.3 14.8 5.3 5.8 14.8 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal PNISR PF15996.5 KEZ46705.1 - 6.9 6.9 9.4 9.9 6.4 9.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF1645 PF07816.11 KEZ46705.1 - 9.4 6.8 24.4 27 5.2 24.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Fibrillarin PF01269.17 KEZ46706.1 - 8.8e-95 316.1 0.0 1e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KEZ46706.1 - 4.7e-08 33.0 0.0 6.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KEZ46706.1 - 0.0051 16.6 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KEZ46706.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KEZ46706.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KEZ46706.1 - 0.21 11.4 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L22 PF00237.19 KEZ46707.1 - 2.5e-42 143.3 0.0 3.5e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 KEZ46707.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain Hydrolase_4 PF12146.8 KEZ46709.1 - 2.3e-45 154.7 0.0 2.8e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KEZ46709.1 - 1.6e-14 55.0 0.4 2.3e-14 54.5 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KEZ46709.1 - 5.8e-11 42.5 0.1 1.3e-10 41.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KEZ46709.1 - 0.00025 20.6 0.2 0.053 13.0 0.1 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KEZ46709.1 - 0.071 12.9 0.8 3.2 7.5 0.0 2.7 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase CTD_bind PF04818.13 KEZ46710.1 - 3.3e-18 66.3 0.0 1.2e-17 64.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 KEZ46710.1 - 0.00073 19.7 1.3 0.0013 18.9 0.4 1.9 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF641 PF04859.12 KEZ46710.1 - 0.11 12.9 2.2 1.8 8.9 0.1 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 KEZ46710.1 - 0.12 11.3 1.5 0.19 10.6 1.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF349 PF03993.12 KEZ46710.1 - 0.74 10.2 3.4 3.2 8.1 3.4 2.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) YkyA PF10368.9 KEZ46710.1 - 0.74 9.5 4.3 1.6 8.4 4.3 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Clathrin_lg_ch PF01086.17 KEZ46711.1 - 2.8e-74 250.1 3.2 3.1e-74 249.9 3.2 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF3274 PF11678.8 KEZ46711.1 - 0.0011 18.3 0.5 0.0013 18.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3274) RGS-like PF09128.11 KEZ46711.1 - 0.015 15.0 0.3 0.023 14.4 0.3 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain rve_3 PF13683.6 KEZ46711.1 - 0.034 13.9 0.5 0.081 12.7 0.5 1.7 1 0 0 1 1 1 0 Integrase core domain COX7a PF02238.15 KEZ46712.1 - 2e-19 69.7 2.5 2.3e-19 69.5 2.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII EF-hand_1 PF00036.32 KEZ46713.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KEZ46713.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KEZ46713.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KEZ46713.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KEZ46713.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KEZ46713.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KEZ46713.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KEZ46713.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KEZ46713.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KEZ46713.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KEZ46713.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KEZ46713.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 KEZ46713.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 KEZ46713.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 KEZ46713.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 KEZ46713.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KEZ46713.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KEZ46713.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 KEZ46713.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 KEZ46713.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 KEZ46713.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 KEZ46713.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KEZ46713.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 KEZ46713.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 KEZ46713.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 KEZ46713.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein Adaptin_N PF01602.20 KEZ46714.1 - 5.3e-147 490.5 1.5 6.2e-147 490.3 1.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KEZ46714.1 - 1.8e-16 60.4 0.0 4.9e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KEZ46714.1 - 8.7e-08 32.4 8.5 0.00035 20.6 0.0 4.8 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ46714.1 - 3.8e-07 30.4 1.1 0.067 13.6 0.0 4.6 6 1 0 6 6 6 2 HEAT repeats HEAT PF02985.22 KEZ46714.1 - 5.7e-05 23.0 1.3 4.3 7.9 0.1 5.1 4 0 0 4 4 4 2 HEAT repeat DUF3730 PF12530.8 KEZ46714.1 - 0.00062 19.4 0.2 0.029 13.9 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT_EZ PF13513.6 KEZ46714.1 - 0.0078 16.7 0.3 43 4.8 0.0 5.2 4 1 1 5 5 5 0 HEAT-like repeat Arm PF00514.23 KEZ46714.1 - 0.089 12.9 0.9 1.1e+02 3.1 0.1 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sec39 PF08314.11 KEZ46715.1 - 5.4e-216 719.5 0.0 1.3e-191 638.9 0.0 2.0 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Ndufs5 PF10200.9 KEZ46716.1 - 0.00049 20.3 0.0 0.00064 19.9 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KEZ46716.1 - 0.0085 16.4 0.3 0.017 15.5 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 KEZ46716.1 - 0.063 13.5 0.1 0.091 13.0 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb RRM_1 PF00076.22 KEZ46717.1 - 5.1e-20 71.1 0.0 7.8e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ46717.1 - 2.8e-05 23.7 0.0 4.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MarR_2 PF12802.7 KEZ46718.1 - 0.083 12.8 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 MarR family SMC_N PF02463.19 KEZ46719.1 - 6.2e-60 202.4 0.0 2.8e-59 200.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KEZ46719.1 - 1.6e-25 89.7 0.0 1.3e-24 86.8 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KEZ46719.1 - 4.7e-08 33.2 17.2 5.7e-05 23.1 0.2 3.8 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KEZ46719.1 - 5.4e-08 32.5 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KEZ46719.1 - 1.9e-05 24.6 12.5 1.9e-05 24.6 12.5 4.7 2 2 1 3 3 3 1 AAA ATPase domain Tropomyosin PF00261.20 KEZ46719.1 - 0.0017 17.8 26.1 0.0017 17.8 26.1 5.9 4 3 2 6 6 6 1 Tropomyosin SbcCD_C PF13558.6 KEZ46719.1 - 0.0078 16.4 0.0 0.064 13.5 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit TFIIE_alpha PF02002.17 KEZ46720.1 - 2e-15 56.5 0.3 3.9e-15 55.6 0.3 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit zf-CCHC_2 PF13696.6 KEZ46720.1 - 0.0048 16.7 3.8 0.02 14.7 0.7 2.2 2 0 0 2 2 2 1 Zinc knuckle zf_UBZ PF18439.1 KEZ46720.1 - 0.06 12.9 0.9 5.8 6.6 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KEZ46720.1 - 0.12 12.5 0.4 0.28 11.3 0.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 KEZ46720.1 - 0.13 12.1 2.7 3.5 7.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 KEZ46720.1 - 0.15 12.1 0.5 0.46 10.6 0.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 KEZ46720.1 - 0.16 11.9 1.8 3.5 7.6 2.5 2.3 1 1 1 2 2 2 0 Nudix N-terminal FAM176 PF14851.6 KEZ46720.1 - 0.41 10.3 13.2 2.2 7.9 3.2 3.0 3 0 0 3 3 3 0 FAM176 family Astro_capsid_p PF12226.8 KEZ46720.1 - 2 7.5 5.5 3.9 6.5 5.5 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_B_thumb PF14791.6 KEZ46721.1 - 7.6e-20 70.8 0.1 1.5e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KEZ46721.1 - 3.9e-18 65.7 0.0 6.7e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KEZ46721.1 - 4.6e-11 42.9 0.0 7.8e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Sec7 PF01369.20 KEZ46722.1 - 2.3e-30 105.7 0.1 3.5e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KEZ46722.1 - 1.4e-05 25.6 0.1 3.9e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KEZ46722.1 - 6.9e-05 23.2 0.1 0.00015 22.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain NCBP3 PF10309.9 KEZ46723.1 - 5.5e-23 80.6 0.1 2.9e-22 78.2 0.0 2.1 2 0 0 2 2 2 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KEZ46723.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain Glyco_transf_41 PF13844.6 KEZ46724.1 - 1e-71 241.8 0.0 1.2e-38 132.8 0.0 3.2 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KEZ46724.1 - 7.3e-14 50.9 0.8 0.0054 16.5 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46724.1 - 9.8e-11 41.0 0.4 0.0055 16.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ46724.1 - 4.5e-10 38.8 1.0 0.98 9.7 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ46724.1 - 8.8e-09 35.2 0.1 0.018 15.4 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ46724.1 - 2.9e-08 33.2 3.7 0.01 15.5 0.0 4.7 3 1 2 5 5 5 2 TPR repeat TPR_10 PF13374.6 KEZ46724.1 - 3.7e-07 29.8 9.0 0.26 11.2 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ46724.1 - 4.5e-07 30.4 1.8 0.76 10.5 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ46724.1 - 6.5e-06 26.3 1.5 0.089 13.1 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46724.1 - 0.00012 22.6 12.8 0.094 13.6 0.0 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46724.1 - 0.00017 22.1 0.2 0.8 10.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ46724.1 - 0.00079 19.3 0.1 0.6 10.3 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ46724.1 - 0.045 13.9 0.1 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.15 KEZ46725.1 - 2.5e-79 266.3 0.0 3.6e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KEZ46725.1 - 4.1e-31 107.6 0.2 9.2e-31 106.4 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KEZ46725.1 - 2.5e-25 88.3 0.2 1.2e-24 86.1 0.1 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Ribosomal_L11_N PF03946.14 KEZ46725.1 - 1.9e-20 72.4 0.0 5.3e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain zf-Sec23_Sec24 PF04810.15 KEZ46725.1 - 3.4e-16 59.0 6.3 6.2e-16 58.2 6.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Ribosomal_L11 PF00298.19 KEZ46725.1 - 9.6e-16 58.1 0.2 1.9e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Gelsolin PF00626.22 KEZ46725.1 - 1.2e-13 50.8 0.0 3.2e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KEZ46725.1 - 0.033 13.6 0.2 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cpn60_TCP1 PF00118.24 KEZ46726.1 - 2.6e-136 455.1 7.7 3.6e-136 454.7 7.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 KEZ46726.1 - 0.099 11.8 1.0 1 8.5 0.1 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 KEZ46727.1 - 1.1e-29 103.6 0.1 1.8e-29 103.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KEZ46729.1 - 6e-35 120.8 64.4 1.9e-32 112.6 54.9 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MLTD_N PF06474.12 KEZ46729.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 MltD lipid attachment motif AA_permease_2 PF13520.6 KEZ46730.1 - 2.5e-37 128.7 49.5 2.9e-37 128.5 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ46730.1 - 1.6e-10 40.2 43.4 2.2e-10 39.7 43.4 1.1 1 0 0 1 1 1 1 Amino acid permease GWT1 PF06423.12 KEZ46730.1 - 3.7 7.7 7.7 0.74 9.9 0.6 2.6 2 0 0 2 2 2 0 GWT1 Fungal_trans_2 PF11951.8 KEZ46731.1 - 4.6e-14 52.0 0.0 7.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46731.1 - 1.5e-09 37.8 8.3 2.9e-09 36.9 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fumarate_red_C PF02300.17 KEZ46731.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Fumarate reductase subunit C PhyH PF05721.13 KEZ46732.1 - 4.1e-25 89.3 0.0 6.8e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 KEZ46733.1 - 2e-08 34.8 0.0 3.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NAD_binding_1 PF00175.21 KEZ46734.1 - 1.4e-25 90.0 0.0 3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KEZ46734.1 - 4e-18 65.6 0.0 9.1e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KEZ46734.1 - 1e-05 25.7 0.1 0.00072 19.7 0.0 2.4 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KEZ46734.1 - 0.0041 17.3 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Glyco_hydro_11 PF00457.17 KEZ46735.1 - 2.3e-72 242.3 15.1 2.7e-72 242.1 15.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 V-set_2 PF15910.5 KEZ46736.1 - 0.069 13.2 0.4 0.11 12.6 0.4 1.3 1 0 0 1 1 1 0 ICOS V-set domain Peptidase_C14 PF00656.22 KEZ46737.1 - 3.4e-59 200.8 0.0 4.6e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KEZ46737.1 - 0.09 12.7 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain WW PF00397.26 KEZ46738.1 - 1.3e-12 47.6 3.0 3.2e-12 46.3 3.0 1.7 1 0 0 1 1 1 1 WW domain TPR_2 PF07719.17 KEZ46738.1 - 0.00044 20.2 3.5 0.17 12.1 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat KinB_sensor PF16767.5 KEZ46738.1 - 0.0031 18.0 2.7 0.0031 18.0 2.7 1.6 2 0 0 2 2 2 1 Sensor domain of alginate biosynthesis sensor protein KinB DUF2853 PF11015.8 KEZ46738.1 - 0.037 14.7 4.6 0.87 10.3 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2853) DUF2076 PF09849.9 KEZ46738.1 - 0.039 14.0 36.4 9.5e+02 -0.4 36.4 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_10 PF13374.6 KEZ46738.1 - 0.051 13.5 7.2 0.3 11.0 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46738.1 - 0.39 11.1 4.7 3.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ46738.1 - 1.5 8.6 13.0 0.78 9.5 0.7 3.2 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 KEZ46738.1 - 1.7 8.6 7.7 0.16 11.9 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ish1 PF10281.9 KEZ46739.1 - 1.5e-72 239.5 22.5 6.7e-11 42.3 0.1 8.6 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KEZ46739.1 - 1.1e-10 41.1 0.0 1.5 8.6 0.0 7.1 8 0 0 8 8 8 2 SAP domain HeH PF12949.7 KEZ46739.1 - 7.6e-10 38.3 0.0 2.2 8.1 0.0 6.5 7 0 0 7 7 7 4 HeH/LEM domain Slx4 PF09494.10 KEZ46739.1 - 1.3e-06 28.2 4.4 4.2 7.4 0.0 6.7 6 1 1 7 7 7 1 Slx4 endonuclease DUF445 PF04286.12 KEZ46739.1 - 0.00028 20.8 2.2 0.00074 19.4 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF445) CPSase_sm_chain PF00988.22 KEZ46739.1 - 0.0016 18.3 0.2 2.7 7.8 0.0 4.1 4 1 1 5 5 5 1 Carbamoyl-phosphate synthase small chain, CPSase domain ANAPC2 PF08672.11 KEZ46739.1 - 0.002 18.6 1.4 1.1e+02 3.4 0.1 6.1 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 6PGD PF00393.19 KEZ46739.1 - 0.0091 15.4 6.1 3.2 7.1 0.0 4.1 3 1 1 4 4 4 1 6-phosphogluconate dehydrogenase, C-terminal domain RWP-RK PF02042.15 KEZ46739.1 - 0.02 14.8 0.0 3.1 7.9 0.0 3.8 4 0 0 4 4 4 0 RWP-RK domain TubC_N PF18563.1 KEZ46739.1 - 0.074 13.0 0.1 0.51 10.4 0.0 2.4 3 0 0 3 3 3 0 TubC N-terminal docking domain Thymopoietin PF08198.11 KEZ46739.1 - 0.077 12.6 0.0 28 4.4 0.0 4.0 4 0 0 4 4 4 0 Thymopoietin protein YtxH PF12732.7 KEZ46739.1 - 0.7 10.5 10.1 5.2 7.7 0.2 4.8 5 0 0 5 5 5 0 YtxH-like protein SAM_2 PF07647.17 KEZ46739.1 - 1.3 9.2 6.2 6.4 7.0 0.1 4.8 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) DUF883 PF05957.13 KEZ46739.1 - 6.7 7.4 13.8 20 5.9 0.1 4.9 5 1 0 5 5 4 0 Bacterial protein of unknown function (DUF883) ADSL_C PF10397.9 KEZ46739.1 - 10 6.8 8.0 65 4.2 0.1 4.5 4 2 1 5 5 5 0 Adenylosuccinate lyase C-terminus Cyt_bd_oxida_II PF02322.15 KEZ46740.1 - 0.015 14.7 2.6 0.019 14.4 2.6 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Vac_ImportDeg PF09783.9 KEZ46741.1 - 1e-63 214.0 0.7 1.6e-63 213.3 0.7 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein PM0188 PF11477.8 KEZ46741.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.3 1 1 0 1 1 1 0 Sialyltransferase PMO188 UPF0020 PF01170.18 KEZ46742.1 - 1.8e-08 34.3 0.0 1.7e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ribonuc_P_40 PF08584.11 KEZ46743.1 - 1.2e-24 87.1 0.2 1.3e-14 54.1 0.0 2.3 1 1 1 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit tRNA_lig_CPD PF08302.11 KEZ46744.1 - 6.7e-90 301.0 0.1 9.2e-90 300.5 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KEZ46744.1 - 1.8e-84 283.0 0.0 3.6e-84 282.0 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KEZ46744.1 - 4.7e-51 173.2 0.0 1.1e-50 172.1 0.0 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain DUF2362 PF10154.9 KEZ46744.1 - 0.015 14.3 1.5 0.027 13.4 1.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) RNA_ligase PF09414.10 KEZ46744.1 - 0.025 14.9 0.0 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 RNA ligase AAA_18 PF13238.6 KEZ46744.1 - 0.031 14.8 0.0 0.27 11.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KEZ46744.1 - 0.037 14.5 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KEZ46744.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KEZ46744.1 - 0.15 12.2 0.3 5.2 7.2 0.3 3.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KEZ46745.1 - 3.8e-40 137.4 0.0 9.4e-40 136.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KEZ46745.1 - 2.1e-18 66.0 0.1 4.3e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KEZ46745.1 - 3.8e-07 29.8 0.0 8.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEZ46745.1 - 0.00019 21.8 1.7 0.02 15.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KEZ46745.1 - 0.0002 21.4 0.6 0.00082 19.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KEZ46745.1 - 0.00033 20.4 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KEZ46745.1 - 0.0018 18.5 0.0 0.012 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KEZ46745.1 - 0.0051 16.3 0.6 0.069 12.6 0.1 2.4 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 KEZ46745.1 - 0.0082 16.4 4.6 0.081 13.2 0.0 3.2 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KEZ46745.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KEZ46745.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 KEZ46745.1 - 0.015 15.5 4.6 0.041 14.1 4.6 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF815 PF05673.13 KEZ46745.1 - 0.041 13.0 0.0 0.088 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KEZ46745.1 - 0.076 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KEZ46745.1 - 0.11 12.2 1.5 0.31 10.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KEZ46745.1 - 0.17 11.4 0.0 0.44 10.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KEZ46745.1 - 0.17 11.7 2.9 0.51 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Adaptin_N PF01602.20 KEZ46746.1 - 1e-95 321.3 3.1 1.7e-95 320.5 3.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KEZ46746.1 - 1e-58 197.2 0.5 2.1e-58 196.2 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KEZ46746.1 - 2e-56 189.5 0.0 5.2e-56 188.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KEZ46746.1 - 8.8e-14 51.9 0.5 9.3e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KEZ46746.1 - 1e-08 35.4 4.9 0.00049 20.4 0.0 5.1 1 1 3 4 4 4 3 HEAT repeats Coatomer_g_Cpla PF16381.5 KEZ46746.1 - 6.7e-05 23.0 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KEZ46746.1 - 0.0012 18.9 0.8 4.9 7.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat DUF2948 PF11164.8 KEZ46746.1 - 0.016 15.2 1.3 0.16 12.0 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) AP4E_app_platf PF14807.6 KEZ46746.1 - 0.052 13.9 0.2 0.18 12.1 0.2 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 KEZ46746.1 - 0.11 13.1 1.7 9.1 6.9 0.0 3.8 3 0 0 3 3 3 0 HEAT-like repeat Mago_nashi PF02792.14 KEZ46747.1 - 2.1e-72 241.9 0.2 2.4e-72 241.7 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein UBD PF16455.5 KEZ46748.1 - 2e-39 134.0 0.0 3.1e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KEZ46748.1 - 6.4e-07 29.0 0.0 9.7e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KEZ46748.1 - 0.00026 20.7 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KEZ46748.1 - 0.021 15.3 0.0 0.064 13.8 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Nop52 PF05997.12 KEZ46749.1 - 3.2e-53 180.7 0.0 3.9e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF3808 PF10300.9 KEZ46750.1 - 3.6e-128 428.3 0.0 5.4e-128 427.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 KEZ46750.1 - 2.2 8.8 5.2 0.91 10.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.13 KEZ46751.1 - 3.1e-22 78.4 13.7 4.2e-22 78.0 13.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PGK PF00162.19 KEZ46752.1 - 1e-150 501.9 0.6 1.2e-150 501.7 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 KEZ46752.1 - 8.3e-05 22.5 0.1 0.015 15.3 0.0 3.1 3 1 0 3 3 3 1 PA domain DUF3530 PF12048.8 KEZ46752.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) AlaDh_PNT_C PF01262.21 KEZ46752.1 - 0.11 11.8 1.7 0.2 10.9 1.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Brix PF04427.18 KEZ46753.1 - 1.2e-47 162.6 0.0 1.7e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF4455 PF14643.6 KEZ46753.1 - 0.0013 17.5 7.0 0.0018 17.0 7.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) DUF1168 PF06658.12 KEZ46753.1 - 0.022 14.6 11.9 0.056 13.3 11.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) V_ATPase_I PF01496.19 KEZ46753.1 - 0.083 10.8 0.6 0.11 10.4 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KEZ46753.1 - 0.13 12.3 3.7 0.19 11.8 3.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus VPS38 PF17649.1 KEZ46753.1 - 0.25 10.2 1.5 0.35 9.7 1.5 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 DEAD PF00270.29 KEZ46754.1 - 8.5e-48 162.4 0.0 1.3e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ46754.1 - 1.7e-31 108.8 0.4 2.2e-29 102.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KEZ46754.1 - 2.4e-05 24.4 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KEZ46754.1 - 0.0005 19.4 0.9 0.00095 18.4 0.1 1.7 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 KEZ46754.1 - 0.0067 16.8 0.0 0.55 10.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain Terminase_6 PF03237.15 KEZ46754.1 - 0.096 12.3 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Terminase-like family Kinesin PF00225.23 KEZ46755.1 - 6.8e-57 192.9 0.0 1.2e-56 192.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KEZ46755.1 - 1.7e-08 34.5 0.0 4.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding bZIP_2 PF07716.15 KEZ46755.1 - 1.1 9.4 9.3 4.1 7.6 3.5 3.2 3 0 0 3 3 3 0 Basic region leucine zipper SET PF00856.28 KEZ46757.1 - 3.5e-12 47.0 0.0 1.2e-11 45.3 0.0 1.8 1 1 0 1 1 1 1 SET domain SRP_SPB PF02978.19 KEZ46757.1 - 0.15 12.7 0.1 0.34 11.6 0.1 1.7 1 0 0 1 1 1 0 Signal peptide binding domain Ras PF00071.22 KEZ46759.1 - 5e-50 169.3 0.0 6e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KEZ46759.1 - 1.1e-21 77.2 0.0 1.6e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KEZ46759.1 - 2.7e-05 23.7 0.0 4.8e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KEZ46759.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KEZ46759.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 KEZ46759.1 - 0.23 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 KEZ46760.1 - 2.5e-45 155.0 13.2 2.5e-45 155.0 13.2 5.7 3 2 2 5 5 5 1 Salt tolerance down-regulator Mem_trans PF03547.18 KEZ46760.1 - 0.092 11.1 0.0 0.95 7.8 0.0 2.1 1 1 0 1 1 1 0 Membrane transport protein NPR2 PF06218.11 KEZ46760.1 - 0.18 10.5 0.3 0.4 9.4 0.3 1.5 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Pre-PUA PF17832.1 KEZ46761.1 - 1.6e-19 70.4 0.1 6.6e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 KEZ46761.1 - 3.9e-14 52.4 0.6 3.6e-13 49.3 0.6 2.2 1 1 0 1 1 1 1 PUA domain Inhibitor_I78 PF11720.8 KEZ46761.1 - 1.3e-08 34.7 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KEZ46761.1 - 0.0043 17.7 0.2 0.012 16.3 0.2 1.7 1 0 0 1 1 1 1 Potato inhibitor I family ChAPs PF09295.10 KEZ46763.1 - 4.6e-149 496.7 0.0 5.8e-149 496.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KEZ46763.1 - 0.00012 22.6 3.8 2.7 9.0 0.0 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46763.1 - 0.00015 22.2 0.0 1 9.9 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ46763.1 - 0.00025 20.9 0.3 0.63 10.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ46763.1 - 0.0023 18.1 1.7 0.011 15.9 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46763.1 - 0.0028 17.8 0.7 0.49 10.7 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ46763.1 - 0.0077 16.2 0.4 4.7 7.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ46763.1 - 0.04 13.8 0.1 9.5 6.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ46763.1 - 0.041 14.1 0.9 5.8 7.2 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AdoHcyase PF05221.17 KEZ46764.1 - 1e-129 431.9 0.0 1e-73 248.1 0.1 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KEZ46764.1 - 1.6e-84 281.9 2.7 2.4e-84 281.3 2.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KEZ46764.1 - 5.8e-08 32.3 0.2 1.1e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KEZ46764.1 - 0.0035 16.9 0.2 0.0062 16.1 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 KEZ46764.1 - 0.027 14.2 0.2 0.054 13.2 0.2 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KEZ46764.1 - 0.036 14.3 0.1 0.075 13.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KEZ46764.1 - 0.053 13.4 0.6 0.096 12.6 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain JAB PF01398.21 KEZ46765.1 - 2.8e-08 33.7 0.2 3.1e-07 30.4 0.2 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease 2-Hacid_dh_C PF02826.19 KEZ46767.1 - 4.6e-54 182.5 0.0 6.6e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KEZ46767.1 - 1.6e-20 73.1 0.0 4.1e-20 71.8 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KEZ46767.1 - 8.3e-06 26.1 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 KEZ46768.1 - 5.8e-08 32.7 11.1 8.7e-08 32.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 KEZ46768.1 - 4.4 6.0 13.2 5.6 5.6 13.2 1.1 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 KEZ46768.1 - 7.3 6.4 12.8 11 5.8 12.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Cid2 PF09774.9 KEZ46769.1 - 1.2e-54 185.1 0.0 1.4e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 KEZ46770.1 - 1.3e-197 657.8 25.8 1.1e-196 654.8 15.3 2.8 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KEZ46770.1 - 1e-22 80.4 25.1 0.0001 22.7 0.1 8.3 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ46770.1 - 1.6e-21 74.6 23.3 0.00011 22.0 0.1 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ46770.1 - 6.4e-17 61.9 27.6 0.00047 20.8 0.0 9.3 8 1 3 11 11 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46770.1 - 2.3e-16 59.1 25.3 0.033 15.0 0.0 10.8 7 4 4 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ46770.1 - 5.1e-14 51.4 19.8 1.5e-06 27.7 0.2 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46770.1 - 7.3e-13 47.6 17.8 0.00013 21.9 0.1 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ46770.1 - 1.8e-12 46.7 13.9 6.5e-06 25.7 0.1 6.0 6 0 0 6 6 6 3 TPR repeat ANAPC3 PF12895.7 KEZ46770.1 - 4.1e-12 46.2 13.6 0.00027 21.1 0.2 5.2 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KEZ46770.1 - 1.1e-08 35.1 11.5 0.006 16.7 0.1 6.6 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KEZ46770.1 - 4.1e-08 32.8 14.6 0.00059 19.1 0.7 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ46770.1 - 5e-07 29.6 12.9 0.44 11.0 0.0 9.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ46770.1 - 1.9e-06 28.1 26.6 0.018 15.3 0.2 7.8 5 3 1 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ46770.1 - 6.5e-06 26.3 14.1 0.023 15.3 2.9 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ46770.1 - 1.7e-05 24.4 10.1 0.68 9.3 1.8 4.1 3 1 0 4 4 4 3 MalT-like TPR region TPR_7 PF13176.6 KEZ46770.1 - 0.00057 19.7 14.1 5.2 7.3 0.0 7.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 KEZ46770.1 - 0.014 15.4 0.1 0.16 12.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PAC3 PF10178.9 KEZ46770.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 TPR_6 PF13174.6 KEZ46770.1 - 0.12 13.1 25.9 0.91 10.3 0.2 9.1 10 0 0 10 10 9 0 Tetratricopeptide repeat BTAD PF03704.17 KEZ46770.1 - 3.7 8.0 10.7 3.1 8.2 1.8 4.0 3 1 1 4 4 3 0 Bacterial transcriptional activator domain MIT PF04212.18 KEZ46770.1 - 9.6 6.4 17.7 3.4 7.8 1.0 6.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain DAGK_cat PF00781.24 KEZ46771.1 - 4.5e-23 81.2 0.1 1.1e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NPCBM_assoc PF10633.9 KEZ46771.1 - 0.097 12.9 0.1 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF676 PF05057.14 KEZ46772.1 - 3.6e-08 33.2 0.0 5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ46772.1 - 8.4e-05 23.3 0.0 0.00012 22.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 KEZ46772.1 - 0.0004 20.4 0.0 0.00054 20.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.13 KEZ46772.1 - 0.00053 19.8 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF829 PF05705.14 KEZ46772.1 - 0.0033 17.3 0.0 0.0041 17.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_9 PF10081.9 KEZ46772.1 - 0.005 16.0 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Abhydrolase_8 PF06259.12 KEZ46772.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KEZ46772.1 - 0.015 14.6 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 KEZ46772.1 - 0.066 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LIDHydrolase PF10230.9 KEZ46772.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase DUF726 PF05277.12 KEZ46772.1 - 0.13 11.1 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Lipase_3 PF01764.25 KEZ46772.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 KEZ46773.1 - 1.4e-06 28.0 0.0 3.2e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KEZ46773.1 - 0.0018 19.0 0.1 0.0027 18.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KEZ46773.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein NACHT PF05729.12 KEZ46774.1 - 0.094 12.6 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain PGAP1 PF07819.13 KEZ46774.1 - 0.2 11.3 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Glyco_hydro_18 PF00704.28 KEZ46775.1 - 2.6e-40 139.1 0.5 1e-39 137.1 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KEZ46775.1 - 7.1e-17 61.2 1.0 3e-07 30.4 0.0 3.5 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.19 KEZ46775.1 - 4.9e-06 26.9 7.7 4.9e-06 26.9 7.7 3.3 3 1 0 3 3 3 1 Chitin recognition protein DUF1349 PF07081.11 KEZ46776.1 - 6.3e-23 81.4 0.0 7.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Abhydrolase_1 PF00561.20 KEZ46777.1 - 3.8e-09 36.6 0.0 1.1e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ46777.1 - 1.4e-05 24.5 0.0 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S24 PF00717.23 KEZ46779.1 - 1.5e-07 31.2 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Mpv17_PMP22 PF04117.12 KEZ46780.1 - 4.5e-19 68.4 2.3 1.2e-18 67.1 0.2 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family tRNA-synt_1b PF00579.25 KEZ46781.1 - 3e-56 190.9 0.0 3.7e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ATP_bind_1 PF03029.17 KEZ46782.1 - 2.7e-71 240.2 0.1 9.2e-71 238.4 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KEZ46782.1 - 1.8e-05 23.9 0.2 0.0084 15.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KEZ46782.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KEZ46782.1 - 0.00027 21.2 0.0 0.0017 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KEZ46782.1 - 0.0005 19.7 0.1 0.023 14.2 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF4455 PF14643.6 KEZ46782.1 - 0.00068 18.4 0.2 0.00099 17.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) AAA_30 PF13604.6 KEZ46782.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KEZ46782.1 - 0.001 18.3 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain MMR_HSR1 PF01926.23 KEZ46782.1 - 0.0011 19.0 0.0 0.0087 16.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KEZ46782.1 - 0.0014 19.1 0.0 0.0032 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KEZ46782.1 - 0.0014 18.6 0.1 2.8 7.8 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase Zeta_toxin PF06414.12 KEZ46782.1 - 0.0014 18.0 0.2 0.0043 16.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 KEZ46782.1 - 0.0019 17.5 0.0 0.06 12.5 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit Roc PF08477.13 KEZ46782.1 - 0.002 18.4 0.0 2.5 8.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KEZ46782.1 - 0.002 18.3 0.0 0.0044 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KEZ46782.1 - 0.0031 17.1 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 KEZ46782.1 - 0.0034 17.3 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain CLP1_P PF16575.5 KEZ46782.1 - 0.004 17.0 0.0 0.091 12.5 0.0 2.6 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FeoB_N PF02421.18 KEZ46782.1 - 0.0044 16.6 0.0 0.095 12.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B PRK PF00485.18 KEZ46782.1 - 0.0062 16.3 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 KEZ46782.1 - 0.0089 15.5 0.1 2.1 7.8 0.0 2.7 3 1 0 3 3 2 1 ADP-ribosylation factor family IlvC PF01450.19 KEZ46782.1 - 0.011 16.0 1.2 4 7.7 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain cobW PF02492.19 KEZ46782.1 - 0.011 15.3 0.1 0.46 10.0 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KEZ46782.1 - 0.017 15.1 0.1 0.069 13.1 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KEZ46782.1 - 0.019 15.5 0.6 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 KEZ46782.1 - 0.022 14.2 0.1 1.2 8.5 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein TsaE PF02367.17 KEZ46782.1 - 0.042 13.9 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KEZ46782.1 - 0.063 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 KEZ46782.1 - 0.065 12.9 0.6 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.20 KEZ46782.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.14 KEZ46782.1 - 0.075 12.2 0.0 0.21 10.8 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 KEZ46782.1 - 0.1 13.1 0.2 20 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 KEZ46782.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 KEZ46782.1 - 0.15 11.5 0.2 8.8 5.7 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 KEZ46782.1 - 0.16 12.3 0.1 0.34 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain DNA_RNApol_7kD PF03604.13 KEZ46783.1 - 4.4e-10 39.0 5.2 6.4e-10 38.5 5.2 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-C4_ClpX PF06689.13 KEZ46783.1 - 0.01 15.7 2.7 0.44 10.5 0.1 2.3 2 0 0 2 2 2 0 ClpX C4-type zinc finger zinc_ribbon_6 PF14599.6 KEZ46783.1 - 0.2 11.7 2.5 0.31 11.1 2.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon TF_Zn_Ribbon PF08271.12 KEZ46783.1 - 0.25 10.9 7.4 0.27 10.8 0.3 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding Aldo_ket_red PF00248.21 KEZ46784.1 - 2e-46 158.5 0.0 1.4e-44 152.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HLH PF00010.26 KEZ46785.1 - 7.5e-10 38.6 0.0 7.5e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hamartin PF04388.12 KEZ46785.1 - 0.23 10.1 5.2 0.32 9.6 5.2 1.2 1 0 0 1 1 1 0 Hamartin protein KAR9 PF08580.10 KEZ46785.1 - 1.1 7.8 5.8 1.3 7.4 5.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 UQ_con PF00179.26 KEZ46787.1 - 6.9e-39 132.7 0.0 1e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KEZ46787.1 - 0.0034 17.1 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B SOG2 PF10428.9 KEZ46788.1 - 0.00012 21.4 2.0 0.00032 20.1 2.0 1.6 1 0 0 1 1 1 1 RAM signalling pathway protein TPR_9 PF13371.6 KEZ46788.1 - 0.092 12.9 2.2 0.39 10.9 2.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46788.1 - 0.35 11.4 2.2 24 5.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46788.1 - 0.78 10.7 4.8 28 5.9 0.2 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 KEZ46789.1 - 1.8e-53 181.6 0.0 2.5e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46789.1 - 2.4e-32 112.2 0.0 3.3e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ46789.1 - 0.00094 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KEZ46789.1 - 0.00096 18.5 0.0 0.0042 16.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KEZ46789.1 - 0.0014 18.1 0.1 0.0048 16.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family UL11 PF11094.8 KEZ46789.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Membrane-associated tegument protein FTA2 PF13095.6 KEZ46789.1 - 0.012 15.3 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 KEZ46789.1 - 0.047 12.7 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 KEZ46789.1 - 0.067 12.0 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KEZ46789.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 KEZ46790.1 - 1.8e-51 175.0 0.0 2.5e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46790.1 - 5.8e-24 84.8 0.0 1.1e-23 83.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KEZ46790.1 - 0.026 13.9 0.4 0.048 13.0 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KEZ46790.1 - 0.031 13.3 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KEZ46790.1 - 0.073 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Trypan_PARP PF05887.11 KEZ46790.1 - 0.61 10.1 7.6 2.1 8.3 7.6 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TMA7 PF09072.10 KEZ46791.1 - 5.1e-26 91.3 19.7 5.7e-26 91.1 19.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Amidase PF01425.21 KEZ46792.1 - 6.4e-94 315.5 0.0 9.3e-94 314.9 0.0 1.2 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 KEZ46793.1 - 2.4e-13 49.7 6.1 1.4e-08 34.0 1.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 KEZ46793.1 - 4.3e-08 32.5 33.4 1.1e-05 24.6 9.6 3.6 2 1 2 4 4 4 3 Major Facilitator Superfamily CENP-B_N PF04218.13 KEZ46793.1 - 0.0062 16.1 0.2 0.016 14.8 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HlyIII PF03006.20 KEZ46794.1 - 9.4e-67 225.0 12.8 1.4e-66 224.5 12.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related TssN PF17555.2 KEZ46794.1 - 0.085 12.2 7.7 0.44 9.9 1.2 2.2 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF996 PF06195.13 KEZ46794.1 - 0.12 12.7 3.8 0.22 11.8 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF996) Bax1-I PF01027.20 KEZ46794.1 - 1.3 8.8 12.3 1.3 8.8 10.9 1.6 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 ELYS-bb PF16687.5 KEZ46795.1 - 0.028 13.0 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin TPR_19 PF14559.6 KEZ46796.1 - 3.1e-05 24.4 1.8 0.019 15.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KEZ46796.1 - 0.015 15.9 0.1 1.5 9.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KEZ46796.1 - 0.049 13.9 0.0 0.22 11.7 0.0 2.0 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FXMRP1_C_core PF12235.8 KEZ46797.1 - 0.23 12.1 2.3 0.52 10.9 2.3 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal ArgJ PF01960.18 KEZ46798.1 - 1.1e-11 44.1 0.0 1.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 ArgJ family FPP PF05911.11 KEZ46798.1 - 0.0012 17.1 1.9 0.0016 16.7 1.9 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil CtIP_N PF10482.9 KEZ46798.1 - 0.0027 17.7 4.6 0.0027 17.7 4.6 2.1 3 0 0 3 3 3 1 Tumour-suppressor protein CtIP N-terminal domain ATG16 PF08614.11 KEZ46798.1 - 0.0039 17.4 4.0 0.0076 16.5 4.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4482 PF14818.6 KEZ46798.1 - 0.071 14.0 5.1 7.3 7.5 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) HemX PF04375.14 KEZ46798.1 - 0.12 11.6 2.7 0.2 10.9 2.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase zf-C2H2_9 PF16293.5 KEZ46798.1 - 0.13 12.1 3.0 8.1 6.4 0.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Fez1 PF06818.15 KEZ46798.1 - 0.54 10.7 8.8 0.48 10.8 6.4 1.9 2 0 0 2 2 2 0 Fez1 CorA PF01544.18 KEZ46798.1 - 0.74 9.1 3.3 1.3 8.2 3.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Atg14 PF10186.9 KEZ46798.1 - 1.2 8.1 5.6 2.1 7.4 5.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HSP70 PF00012.20 KEZ46799.1 - 1.1e-08 33.8 0.1 5.7e-08 31.4 0.1 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ46799.1 - 0.006 15.4 0.0 0.022 13.6 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Fringe PF02434.16 KEZ46800.1 - 6.4e-07 29.1 0.1 7.5e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 KEZ46800.1 - 0.0034 17.3 0.7 0.0059 16.5 0.7 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 KEZ46800.1 - 0.3 11.0 1.6 0.53 10.2 1.6 1.3 1 0 0 1 1 1 0 PAN domain Oxysterol_BP PF01237.18 KEZ46801.1 - 6.4e-58 196.4 0.2 9.1e-56 189.3 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein GMC_oxred_N PF00732.19 KEZ46802.1 - 3.4e-45 154.7 0.0 5.9e-45 153.9 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ46802.1 - 1.5e-25 90.4 0.0 3e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KEZ46802.1 - 8.8e-06 25.0 0.0 0.00027 20.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KEZ46802.1 - 0.00025 19.9 0.0 0.0013 17.5 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 KEZ46802.1 - 0.0011 19.2 0.1 0.0034 17.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KEZ46802.1 - 0.0019 17.8 1.6 0.0056 16.3 1.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KEZ46802.1 - 0.0024 17.1 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KEZ46802.1 - 0.014 14.7 0.1 0.028 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KEZ46802.1 - 0.015 15.5 0.2 0.032 14.5 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KEZ46802.1 - 0.017 14.4 0.1 0.063 12.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ46802.1 - 0.021 13.9 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KEZ46802.1 - 0.092 12.0 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Tim44 PF04280.15 KEZ46803.1 - 2.8e-37 128.1 0.1 1.7e-36 125.5 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain Cytomega_UL84 PF06284.11 KEZ46803.1 - 0.033 12.7 3.5 0.051 12.0 3.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Presenilin PF01080.17 KEZ46803.1 - 1.4 7.6 10.3 2.2 7.0 10.3 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KEZ46803.1 - 2.8 6.5 8.8 3.7 6.1 8.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_C97 PF05903.14 KEZ46804.1 - 2.3e-34 118.4 0.0 2.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KEZ46804.1 - 0.034 14.5 0.1 0.055 13.8 0.1 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.13 KEZ46805.1 - 6.5e-35 119.2 0.1 1.8e-34 117.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KEZ46805.1 - 4e-17 62.3 0.0 9.9e-17 61.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KEZ46805.1 - 0.00021 20.9 0.0 0.00041 19.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KEZ46805.1 - 0.00027 20.9 0.1 0.00069 19.6 0.1 1.7 1 0 0 1 1 1 1 TGS domain BetaGal_dom3 PF13363.6 KEZ46805.1 - 0.03 13.9 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_14 PF13173.6 KEZ46805.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_L21p PF00829.21 KEZ46805.1 - 0.42 10.9 2.5 26 5.1 0.1 2.7 2 0 0 2 2 2 0 Ribosomal prokaryotic L21 protein VPS9 PF02204.18 KEZ46806.1 - 3.6e-18 65.7 0.0 8.4e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KEZ46806.1 - 6.1e-15 55.1 0.9 2.3e-12 46.9 0.1 4.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KEZ46806.1 - 7.4e-14 52.1 0.2 9.7e-05 22.9 0.0 3.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ46806.1 - 3.5e-10 40.2 0.2 0.00017 22.0 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ46806.1 - 3.5e-07 30.0 0.4 0.023 15.2 0.0 5.5 5 1 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 KEZ46806.1 - 3e-05 24.3 0.4 0.065 13.7 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.24 KEZ46806.1 - 0.096 12.7 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 PX domain KKLCAg1 PF15204.6 KEZ46806.1 - 9.7 6.4 9.8 0.061 13.4 0.9 2.0 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 SET PF00856.28 KEZ46807.1 - 5.6e-10 39.9 0.0 3.6e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 SET domain T6SS_VipA PF05591.12 KEZ46807.1 - 0.088 12.6 0.0 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 Ldh_1_N PF00056.23 KEZ46808.1 - 2.7e-44 150.7 0.2 4e-44 150.1 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KEZ46808.1 - 4.8e-24 85.2 0.0 9.4e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DAO PF01266.24 KEZ46808.1 - 0.00026 20.7 1.4 0.001 18.7 1.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KEZ46808.1 - 0.00057 19.2 1.3 0.0016 17.8 1.3 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KEZ46808.1 - 0.0011 18.5 0.2 0.0023 17.5 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 KEZ46808.1 - 0.0015 18.5 0.2 0.0028 17.6 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KEZ46808.1 - 0.003 18.1 0.2 0.0083 16.7 0.2 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KEZ46808.1 - 0.014 15.7 0.2 0.043 14.1 0.2 1.9 1 1 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 KEZ46808.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 KEZ46808.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 KEZ46808.1 - 0.029 14.8 0.0 0.059 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_4 PF02056.16 KEZ46808.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase GFO_IDH_MocA PF01408.22 KEZ46808.1 - 0.12 13.2 0.1 0.22 12.4 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2252 PF10009.9 KEZ46808.1 - 0.15 11.1 0.1 0.53 9.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Acetyltransf_3 PF13302.7 KEZ46809.1 - 4.2e-16 59.9 0.0 6.1e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KEZ46809.1 - 3.2e-07 30.6 0.0 6.8e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Sulfotransfer_4 PF17784.1 KEZ46810.1 - 3.4e-54 183.9 0.0 4.4e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KEZ46810.1 - 0.00062 20.2 1.5 0.16 12.4 0.2 2.4 1 1 1 2 2 2 2 Sulfotransferase family AAA_18 PF13238.6 KEZ46810.1 - 0.059 13.9 0.0 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain CFEM PF05730.11 KEZ46811.1 - 2.4e-07 30.7 9.2 3.4e-07 30.3 9.2 1.2 1 0 0 1 1 1 1 CFEM domain DUF3693 PF12472.8 KEZ46811.1 - 0.098 12.3 0.3 0.25 11.0 0.3 1.6 1 0 0 1 1 1 0 Phage related protein FAD_binding_4 PF01565.23 KEZ46813.1 - 2.5e-23 82.4 3.5 4.3e-23 81.6 3.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KEZ46813.1 - 1.1e-11 44.6 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cyt-b5 PF00173.28 KEZ46814.1 - 2.5e-11 43.5 0.0 3.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2063 PF09836.9 KEZ46814.1 - 0.025 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative DNA-binding domain TNFR_16_TM PF18422.1 KEZ46814.1 - 0.064 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Peptidase_M43 PF05572.13 KEZ46815.1 - 1.7e-16 60.5 0.1 2.9e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KEZ46815.1 - 7.4e-07 29.5 0.0 1.9e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KEZ46815.1 - 1.3e-05 25.7 0.0 5.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KEZ46815.1 - 0.0087 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KEZ46815.1 - 0.017 15.3 0.1 0.036 14.2 0.1 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.24 KEZ46815.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 KEZ46815.1 - 0.037 13.9 0.6 0.073 13.0 0.2 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like TPP_enzyme_N PF02776.18 KEZ46816.1 - 9.2e-55 184.9 0.0 8.3e-54 181.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KEZ46816.1 - 4.7e-50 169.3 0.1 1.2e-48 164.7 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KEZ46816.1 - 2.1e-41 140.9 0.9 4.8e-41 139.7 0.5 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain zf-C2H2 PF00096.26 KEZ46817.1 - 2.2 8.9 10.0 2.5 8.7 0.5 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type GalKase_gal_bdg PF10509.9 KEZ46818.1 - 2.3e-20 71.9 0.0 4e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 KEZ46818.1 - 4.8e-14 52.5 0.1 1.3e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 KEZ46818.1 - 9.1e-14 51.4 2.4 9.1e-14 51.4 2.4 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1998 PF09369.10 KEZ46818.1 - 0.053 14.3 0.1 0.27 12.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1998) HTH_23 PF13384.6 KEZ46818.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 KEZ46818.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 RINGv PF12906.7 KEZ46819.1 - 0.00011 22.2 9.4 0.0002 21.4 9.4 1.4 1 0 0 1 1 1 1 RING-variant domain LTV PF04180.14 KEZ46819.1 - 0.0054 16.5 2.7 0.0071 16.1 2.7 1.1 1 0 0 1 1 1 1 Low temperature viability protein zf-RING_2 PF13639.6 KEZ46819.1 - 0.0077 16.5 10.5 0.012 15.9 10.5 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KEZ46819.1 - 0.014 15.6 4.1 0.014 15.6 4.1 1.6 2 0 0 2 2 1 0 FANCL C-terminal domain CDC45 PF02724.14 KEZ46819.1 - 0.019 13.3 9.8 0.026 12.9 9.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Rad50_zn_hook PF04423.14 KEZ46819.1 - 0.13 12.1 1.8 0.14 12.0 0.3 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Pex14_N PF04695.13 KEZ46819.1 - 0.13 12.9 5.6 0.22 12.2 5.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SDA1 PF05285.12 KEZ46819.1 - 0.31 10.4 10.2 0.4 10.1 10.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KEZ46819.1 - 0.94 7.6 12.0 1.2 7.2 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.9 KEZ46819.1 - 2.6 8.1 15.7 3.8 7.6 15.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-C3HC4 PF00097.25 KEZ46819.1 - 3.7 7.5 8.2 6 6.8 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lin-8 PF03353.15 KEZ46819.1 - 5.9 6.4 11.0 8.9 5.8 11.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist LAP1C PF05609.12 KEZ46819.1 - 7.4 5.5 6.7 9.9 5.1 6.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) zf-RING_4 PF14570.6 KEZ46819.1 - 8 6.3 8.4 14 5.6 8.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SGTA_dimer PF16546.5 KEZ46820.1 - 5.2e-22 77.4 0.8 8.7e-22 76.7 0.8 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KEZ46820.1 - 2.2e-18 65.2 2.1 5.3e-07 29.2 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KEZ46820.1 - 1.4e-16 59.2 5.2 1.7e-06 27.7 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KEZ46820.1 - 5.1e-09 35.7 4.1 0.00019 21.0 1.6 3.0 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 KEZ46820.1 - 8.3e-09 35.2 1.7 5.7e-05 23.2 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46820.1 - 8.9e-09 35.4 6.4 0.0035 18.0 0.4 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46820.1 - 3e-08 33.2 0.7 0.16 12.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ46820.1 - 3.6e-08 33.9 10.9 3.6e-06 27.5 7.2 2.8 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46820.1 - 1.7e-06 28.5 2.4 0.00017 22.1 1.9 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ46820.1 - 1.4e-05 25.3 6.1 3e-05 24.2 2.4 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ46820.1 - 2.4e-05 24.1 1.2 0.027 14.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 KEZ46820.1 - 7.1e-05 22.7 9.1 0.0013 18.6 4.9 2.4 2 0 0 2 2 2 1 STI1 domain TPR_6 PF13174.6 KEZ46820.1 - 0.00026 21.4 3.7 1.1 10.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KEZ46820.1 - 0.00031 20.5 4.2 0.12 12.3 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KEZ46820.1 - 0.00046 20.3 2.1 0.032 14.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 KEZ46820.1 - 0.054 13.9 2.2 5.9 7.3 0.2 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain XPC-binding PF09280.11 KEZ46820.1 - 0.058 13.1 2.2 0.13 12.1 2.2 1.6 1 0 0 1 1 1 0 XPC-binding domain TPR_15 PF13429.6 KEZ46820.1 - 0.11 11.7 4.0 0.21 10.8 4.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 KEZ46820.1 - 0.68 10.0 5.2 0.5 10.5 0.3 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain GerD PF17898.1 KEZ46820.1 - 0.73 9.8 2.2 2.4 8.2 2.2 1.8 1 1 0 1 1 1 0 Spore germination GerD central core domain ABC_tran PF00005.27 KEZ46821.1 - 2.8e-34 118.6 0.0 5.6e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KEZ46821.1 - 1.8e-21 77.0 1.6 3.6e-21 76.0 1.6 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 KEZ46821.1 - 0.00011 22.1 0.1 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KEZ46821.1 - 0.00046 19.7 0.0 0.0055 16.2 0.0 1.8 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KEZ46821.1 - 0.0033 17.3 0.0 0.0095 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system PAM2 PF07145.15 KEZ46821.1 - 0.011 15.4 0.2 0.025 14.3 0.2 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region AAA_30 PF13604.6 KEZ46821.1 - 0.025 14.3 0.8 0.14 11.8 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KEZ46821.1 - 0.032 14.5 0.1 0.14 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KEZ46821.1 - 0.037 14.5 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KEZ46821.1 - 0.062 13.7 0.1 0.71 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 KEZ46821.1 - 0.069 12.7 0.1 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KEZ46821.1 - 0.073 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KEZ46821.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 KEZ46821.1 - 0.089 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KEZ46821.1 - 0.11 13.0 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KEZ46821.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MTABC_N PF16185.5 KEZ46821.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region SbcCD_C PF13558.6 KEZ46821.1 - 0.17 12.2 0.2 1.8 8.8 0.2 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PBP PF01161.20 KEZ46822.1 - 2.1e-07 31.3 0.1 3.3e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Vps35 PF03635.17 KEZ46823.1 - 0 1015.9 0.0 0 1015.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TFR_dimer PF04253.15 KEZ46824.1 - 4.8e-31 107.4 0.0 1e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KEZ46824.1 - 1.2e-13 51.3 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KEZ46824.1 - 1.6e-12 47.3 0.1 3.3e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 PA domain Cwf_Cwc_15 PF04889.12 KEZ46824.1 - 0.032 14.0 1.5 0.053 13.2 1.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_10 PF13374.6 KEZ46825.1 - 2.2e-79 259.4 13.9 4.5e-11 42.2 0.1 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 KEZ46825.1 - 2.2e-64 213.7 36.7 3.4e-16 59.3 0.4 6.8 3 2 5 8 8 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KEZ46825.1 - 1.3e-21 74.9 15.4 0.0027 17.6 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KEZ46825.1 - 6.1e-14 52.1 17.1 1.1e-08 34.8 11.8 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KEZ46825.1 - 5.4e-13 48.0 20.8 0.0046 17.0 0.7 8.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_4 PF07721.14 KEZ46825.1 - 1.6e-12 46.7 10.8 0.11 13.1 0.1 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KEZ46825.1 - 1.7e-12 46.6 11.1 0.026 14.4 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 KEZ46825.1 - 1e-08 34.7 10.5 0.019 15.1 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KEZ46825.1 - 5.7e-08 33.1 14.5 0.12 12.9 0.0 7.3 5 2 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KEZ46825.1 - 1.3e-07 32.1 15.1 0.13 12.9 0.1 7.1 6 3 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KEZ46825.1 - 3.5e-06 27.4 18.4 0.25 12.3 0.0 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 KEZ46825.1 - 3.5e-06 27.0 10.5 0.7 10.4 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 KEZ46825.1 - 4.6e-05 22.7 0.0 9.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.13 KEZ46825.1 - 0.00013 21.7 0.0 0.00057 19.7 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein AAA_22 PF13401.6 KEZ46825.1 - 0.0029 17.9 0.0 0.064 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain SNAP PF14938.6 KEZ46825.1 - 0.0047 16.4 0.3 0.86 9.0 0.0 2.4 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP DUF676 PF05057.14 KEZ46825.1 - 0.0056 16.2 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PPR PF01535.20 KEZ46825.1 - 0.0059 16.8 1.0 27 5.3 0.0 5.3 6 0 0 6 6 5 0 PPR repeat Cutinase PF01083.22 KEZ46825.1 - 0.035 14.1 0.0 0.084 12.8 0.0 1.5 2 0 0 2 2 1 0 Cutinase TPR_11 PF13414.6 KEZ46825.1 - 0.038 13.7 2.0 5.8 6.7 0.0 4.2 4 0 0 4 4 3 0 TPR repeat Abhydrolase_6 PF12697.7 KEZ46825.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family TPR_6 PF13174.6 KEZ46825.1 - 0.35 11.6 15.2 1.8 9.4 0.2 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat AATase PF07247.12 KEZ46826.1 - 1.2e-15 57.1 0.0 1.6e-14 53.3 0.0 2.3 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 KEZ46826.1 - 1.4e-07 31.6 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KEZ46826.1 - 0.0029 16.3 0.0 0.048 12.3 0.0 2.0 2 0 0 2 2 2 1 Condensation domain Glyco_transf_54 PF04666.13 KEZ46827.1 - 2.1e-05 23.6 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region HisKA_7TM PF16927.5 KEZ46827.1 - 0.0031 17.6 4.9 0.6 10.1 0.2 2.2 2 0 0 2 2 2 2 N-terminal 7TM region of histidine kinase DUF4131 PF13567.6 KEZ46827.1 - 0.36 10.5 6.6 4.6 6.9 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YwiC PF14256.6 KEZ46827.1 - 2.5 8.4 7.8 1.6 9.1 3.0 2.3 2 0 0 2 2 2 0 YwiC-like protein RSN1_7TM PF02714.15 KEZ46828.1 - 6.9e-79 265.0 18.5 1.1e-78 264.3 18.5 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KEZ46828.1 - 1.3e-39 135.5 0.8 3e-39 134.3 0.8 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KEZ46828.1 - 4.4e-38 131.3 0.0 6.2e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Glycos_transf_2 PF00535.26 KEZ46830.1 - 6.7e-35 120.4 0.0 8e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KEZ46830.1 - 1.3e-12 48.1 0.0 1.7e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KEZ46830.1 - 8.5e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KEZ46830.1 - 8.9e-05 22.1 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KEZ46830.1 - 0.044 14.3 0.0 0.091 13.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 CSN8_PSD8_EIF3K PF10075.9 KEZ46831.1 - 0.0048 16.9 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PPR_1 PF12854.7 KEZ46831.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 PPR repeat AbiEii PF08843.11 KEZ46832.1 - 0.15 12.0 0.2 1.1 9.2 0.2 1.9 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF2007 PF09413.10 KEZ46833.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein IBR PF01485.21 KEZ46834.1 - 9.6e-08 32.1 35.5 7.4e-06 26.1 11.2 3.5 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain Spt20 PF12090.8 KEZ46835.1 - 3.3e-44 151.2 0.2 3.3e-44 151.2 0.2 9.3 4 1 3 7 7 7 1 Spt20 family ATG27 PF09451.10 KEZ46836.1 - 3.4e-94 315.6 0.0 4.1e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Diphthamide_syn PF01866.17 KEZ46837.1 - 2.5e-118 395.0 0.0 3e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribosomal_S6e PF01092.19 KEZ46838.1 - 1.8e-57 192.8 0.0 3.2e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Stk19 PF10494.9 KEZ46838.1 - 0.044 13.5 0.9 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 DUF16 PF01519.16 KEZ46838.1 - 0.19 12.2 1.8 0.34 11.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Gas_vesicle_C PF01304.17 KEZ46838.1 - 0.38 10.8 2.9 0.99 9.5 2.9 1.7 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Atg14 PF10186.9 KEZ46838.1 - 2.4 7.1 10.3 3.5 6.6 10.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OHCU_decarbox PF09349.10 KEZ46839.1 - 0.048 14.1 0.0 0.055 14.0 0.0 1.1 1 0 0 1 1 1 0 OHCU decarboxylase SEO_C PF14577.6 KEZ46839.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Steroid_dh PF02544.16 KEZ46840.1 - 7.2e-33 113.7 0.2 1.2e-32 113.0 0.2 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KEZ46840.1 - 4.6e-06 26.3 1.8 7e-06 25.7 0.6 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KEZ46840.1 - 0.0048 17.3 0.6 0.0096 16.3 0.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase SOG2 PF10428.9 KEZ46841.1 - 7e-75 253.2 0.0 4e-53 181.4 0.0 4.1 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_4 PF12799.7 KEZ46841.1 - 1.1e-15 57.5 7.6 6.1e-07 29.7 0.3 3.7 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KEZ46841.1 - 9.2e-15 54.2 7.7 4.9e-07 29.4 2.4 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KEZ46841.1 - 0.005 16.8 10.6 0.58 10.4 0.2 5.6 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 KEZ46841.1 - 0.0077 16.6 9.1 18 6.3 0.3 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat DEAD PF00270.29 KEZ46842.1 - 1.7e-18 67.0 0.0 3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KEZ46842.1 - 1.5e-17 64.0 0.0 1.1e-14 54.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KEZ46842.1 - 3.5e-12 46.9 1.3 9.6e-12 45.5 1.3 1.8 1 0 0 1 1 1 1 RecQ zinc-binding HSP70 PF00012.20 KEZ46843.1 - 3.7e-260 864.3 6.1 4.2e-260 864.1 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KEZ46843.1 - 5.9e-17 61.5 0.0 8.7e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KEZ46843.1 - 0.0023 17.7 0.0 0.0085 15.8 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KEZ46843.1 - 0.011 15.1 0.1 0.022 14.0 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 KEZ46843.1 - 0.014 15.8 2.1 9.6 6.7 0.1 3.5 3 1 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KEZ46843.1 - 0.052 13.0 0.0 4.2 6.8 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Golgin_A5 PF09787.9 KEZ46843.1 - 1.2 8.5 9.2 0.74 9.2 5.7 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 RNA12 PF10443.9 KEZ46844.1 - 5.4e-130 434.1 0.1 6.9e-130 433.7 0.1 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 KEZ46844.1 - 1.2e-06 28.2 0.0 8.3e-05 22.3 0.0 3.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 KEZ46844.1 - 0.0095 16.0 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) COPI_C PF06957.11 KEZ46844.1 - 0.028 13.2 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ATPase_2 PF01637.18 KEZ46844.1 - 0.076 12.9 0.2 0.27 11.1 0.2 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea CENP-C_C PF11699.8 KEZ46845.1 - 4.4e-35 119.8 0.4 6.9e-35 119.1 0.4 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 KEZ46845.1 - 8.5e-33 113.9 1.9 8.5e-33 113.9 1.9 3.4 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 KEZ46845.1 - 3e-07 30.1 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Lactamase_B PF00753.27 KEZ46845.1 - 0.022 14.8 2.3 0.081 12.9 0.1 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Cupin_1 PF00190.22 KEZ46845.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin RHD3 PF05879.12 KEZ46846.1 - 0 1035.3 0.0 0 1035.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KEZ46846.1 - 9.9e-07 28.3 0.2 1.6e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KEZ46846.1 - 3.4e-06 27.2 0.0 5.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KEZ46846.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KEZ46846.1 - 0.00079 19.7 0.0 0.0026 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KEZ46846.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Septin DLH PF01738.18 KEZ46847.1 - 3.8e-22 78.9 0.0 5.6e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KEZ46847.1 - 5e-05 23.0 0.0 8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KEZ46847.1 - 0.00014 21.8 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.11 KEZ46847.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF1854 PF08909.11 KEZ46847.1 - 0.19 11.5 0.0 0.96 9.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) MS_channel PF00924.18 KEZ46848.1 - 1.5e-18 67.1 1.1 3e-18 66.1 1.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KEZ46848.1 - 0.013 15.0 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 KEZ46848.1 - 0.058 12.9 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KEZ46848.1 - 0.075 13.5 0.1 0.21 12.1 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Abp2 PF09441.10 KEZ46849.1 - 4.6e-73 244.9 0.0 6.7e-73 244.4 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Spc42p PF11544.8 KEZ46849.1 - 0.048 13.6 0.1 3.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Spindle pole body component Spc42p ARID PF01388.21 KEZ46849.1 - 0.067 13.9 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain Methyltransf_23 PF13489.6 KEZ46850.1 - 2.9e-11 43.5 0.0 3.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46850.1 - 4.8e-08 33.5 0.0 1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46850.1 - 1.2e-06 29.1 0.0 2.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46850.1 - 2.7e-06 28.1 0.0 5.8e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46850.1 - 0.0011 18.8 0.0 0.0026 17.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ46850.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Sds3 PF08598.11 KEZ46851.1 - 4.2e-21 76.0 11.4 6.3e-21 75.4 11.4 1.4 1 1 0 1 1 1 1 Sds3-like Exonuc_VII_L PF02601.15 KEZ46851.1 - 0.64 9.5 5.2 1.1 8.8 5.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Btz PF09405.10 KEZ46852.1 - 0.0035 17.6 0.8 0.0054 17.0 0.1 1.7 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.25 KEZ46853.1 - 5.3e-50 170.2 0.0 1.8e-49 168.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46853.1 - 8.3e-23 81.0 0.0 1.9e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KEZ46853.1 - 0.00049 20.1 0.1 0.00049 20.1 0.1 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KEZ46853.1 - 0.0064 16.1 0.2 0.0064 16.1 0.2 2.1 2 1 0 2 2 2 1 RIO1 family DUF4407 PF14362.6 KEZ46853.1 - 0.36 10.1 14.5 0.34 10.2 8.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 KEZ46854.1 - 1.6e-59 197.6 0.0 2e-21 75.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KEZ46854.1 - 3.3e-10 39.6 0.0 9.8e-06 25.2 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KEZ46854.1 - 1.2e-09 37.8 0.0 0.025 14.4 0.0 3.3 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KEZ46854.1 - 2e-07 30.9 0.3 0.3 11.1 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 KEZ46854.1 - 7.1e-05 22.8 0.0 0.21 11.7 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_8 PF11835.8 KEZ46854.1 - 0.00014 22.0 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain RRM_7 PF16367.5 KEZ46854.1 - 0.0005 20.1 0.1 0.48 10.6 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 KEZ46854.1 - 0.031 14.3 0.1 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif SET_assoc PF11767.8 KEZ46854.1 - 0.054 13.2 0.0 9.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated AlaDh_PNT_N PF05222.15 KEZ46855.1 - 1.1e-22 80.8 0.0 1.5e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Med2 PF11214.8 KEZ46856.1 - 1.1 9.4 3.8 0.41 10.8 0.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 2 GREB1 PF15782.5 KEZ46856.1 - 2.1 5.4 5.1 2.6 5.0 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer APH PF01636.23 KEZ46857.1 - 9.1e-05 22.5 0.0 0.00016 21.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KEZ46857.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KEZ46857.1 - 0.0034 17.0 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KEZ46857.1 - 0.034 13.3 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 Fructosamine kinase Aquarius_N PF16399.5 KEZ46858.1 - 7.6e-301 999.9 0.0 4.5e-229 762.6 0.0 2.2 1 1 1 2 2 2 2 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KEZ46858.1 - 6.9e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KEZ46858.1 - 6.6e-21 75.3 0.0 1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KEZ46858.1 - 7.8e-07 29.0 0.0 0.00078 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KEZ46858.1 - 3.8e-06 27.0 0.0 7.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KEZ46858.1 - 1.7e-05 25.2 0.0 4.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KEZ46858.1 - 0.0012 19.3 0.0 0.0039 17.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KEZ46858.1 - 0.0029 18.0 0.6 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DnaB_C PF03796.15 KEZ46858.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.18 KEZ46858.1 - 0.022 14.5 0.1 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KEZ46858.1 - 0.033 14.5 0.5 0.32 11.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 KEZ46858.1 - 0.042 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.17 KEZ46858.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 KEZ46858.1 - 0.096 11.9 1.3 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KEZ46858.1 - 0.12 12.7 0.0 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 KEZ46858.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 KEZ46858.1 - 0.14 11.6 0.1 0.47 9.9 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Zeta_toxin PF06414.12 KEZ46858.1 - 0.15 11.3 0.0 0.41 9.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin MIF4G PF02854.19 KEZ46859.1 - 1.4e-52 178.5 0.0 2.2e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KEZ46859.1 - 5.3e-15 55.4 0.2 5.3e-15 55.4 0.2 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF4148 PF13663.6 KEZ46859.1 - 0.025 14.7 0.8 11 6.3 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) efThoc1 PF11957.8 KEZ46860.1 - 1.2e-140 469.5 0.1 1.5e-140 469.1 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KEZ46860.1 - 1e-23 84.0 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 KEZ46860.1 - 0.00018 21.7 0.7 0.0008 19.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KEZ46860.1 - 0.015 15.8 0.5 0.049 14.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KEZ46860.1 - 0.019 15.3 0.1 0.065 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 KEZ46860.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KEZ46860.1 - 0.16 12.2 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KEZ46860.1 - 0.2 11.3 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DNA_pol_B PF00136.21 KEZ46861.1 - 6.5e-115 384.5 0.0 9.7e-115 383.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KEZ46861.1 - 5.8e-67 225.0 0.8 9.1e-67 224.4 0.1 1.7 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KEZ46861.1 - 8.2e-41 140.2 0.0 1.5e-40 139.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KEZ46861.1 - 1.4e-24 85.9 7.4 1.4e-24 85.9 7.4 3.2 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KEZ46861.1 - 0.016 14.1 0.2 0.044 12.6 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral VWA_N2 PF16164.5 KEZ46861.1 - 0.16 12.2 0.5 0.44 10.7 0.5 1.7 1 0 0 1 1 1 0 VWA N-terminal WSK PF03832.13 KEZ46861.1 - 0.32 10.7 2.8 2.4 7.9 0.2 2.7 2 0 0 2 2 2 0 WSK motif Asp PF00026.23 KEZ46862.1 - 2.2e-13 50.3 0.0 2.3e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KEZ46862.1 - 0.00013 22.2 0.0 0.0002 21.7 0.0 1.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Ank_2 PF12796.7 KEZ46863.1 - 2e-45 153.3 0.3 8.1e-18 64.8 0.0 6.1 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KEZ46863.1 - 3.3e-43 145.5 7.7 3.4e-11 43.4 0.1 9.6 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KEZ46863.1 - 6e-29 96.9 9.1 0.0047 17.3 0.0 11.1 12 0 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 KEZ46863.1 - 1.7e-26 91.4 9.5 4.5e-05 23.7 0.0 10.4 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 KEZ46863.1 - 1.9e-24 85.4 9.5 0.0085 16.4 0.1 8.7 6 2 2 8 8 8 7 Ankyrin repeats (many copies) DUF5538 PF17692.1 KEZ46864.1 - 0.098 12.7 0.7 0.72 9.9 0.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5538) ssDBP_DBD PF18361.1 KEZ46864.1 - 0.099 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Nop14 PF04147.12 KEZ46865.1 - 0.26 9.4 13.5 0.5 8.5 13.5 1.4 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 KEZ46866.1 - 2.5e-40 138.5 0.0 3.7e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46866.1 - 1.6e-27 96.4 0.0 2.4e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Caldesmon PF02029.15 KEZ46866.1 - 0.00057 18.8 1.4 0.0012 17.7 1.4 1.5 1 0 0 1 1 1 1 Caldesmon Kinase-like PF14531.6 KEZ46866.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KEZ46866.1 - 0.018 14.9 0.0 5.6 6.8 0.0 2.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KEZ46866.1 - 0.22 10.3 0.1 0.78 8.4 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 KEZ46867.1 - 1.2e-59 201.8 0.0 1.8e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46867.1 - 1.9e-19 70.0 0.0 2.9e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KEZ46867.1 - 3.5e-08 33.1 0.0 5.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KEZ46867.1 - 2.4e-05 23.5 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KEZ46867.1 - 0.00092 18.1 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KEZ46867.1 - 0.001 18.7 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KEZ46867.1 - 0.0018 18.2 0.7 0.011 15.7 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KEZ46867.1 - 0.27 10.2 0.1 0.43 9.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zinc_ribbon_16 PF17034.5 KEZ46868.1 - 0.00075 19.7 0.5 0.0019 18.4 0.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Efg1 PF10153.9 KEZ46869.1 - 2e-33 115.1 12.5 2e-33 115.1 12.5 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF1493 PF07377.12 KEZ46869.1 - 0.021 15.3 2.0 0.035 14.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) dsrm PF00035.26 KEZ46870.1 - 0.051 14.3 0.2 0.16 12.7 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif Casein_kappa PF00997.18 KEZ46870.1 - 0.067 13.3 8.2 0.14 12.3 8.2 1.5 1 0 0 1 1 1 0 Kappa casein PTS_2-RNA PF01885.16 KEZ46871.1 - 7.2e-69 231.5 0.0 8.5e-69 231.2 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family UAA PF08449.11 KEZ46873.1 - 7.5e-42 143.6 8.7 1.4e-41 142.7 8.7 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KEZ46873.1 - 5.8e-07 29.7 5.7 5.8e-07 29.7 5.7 3.5 4 0 0 4 4 4 1 EamA-like transporter family Nuc_sug_transp PF04142.15 KEZ46873.1 - 2.5e-06 26.9 1.2 0.0036 16.5 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 KEZ46873.1 - 0.021 13.8 3.7 0.4 9.6 0.1 2.3 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KEZ46873.1 - 0.17 11.2 10.6 1.8 7.9 1.3 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family KH_1 PF00013.29 KEZ46874.1 - 2.7e-40 136.0 10.5 1.5e-15 56.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KEZ46874.1 - 1.1e-09 37.9 9.8 0.015 15.1 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KEZ46874.1 - 9.3e-09 35.0 5.3 0.0088 15.9 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KEZ46874.1 - 8e-05 22.6 6.2 0.22 11.6 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KEZ46874.1 - 0.0079 16.2 0.0 12 6.0 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain Keratin_2_tail PF16210.5 KEZ46874.1 - 0.015 15.6 16.4 0.015 15.6 16.4 1.7 2 0 0 2 2 2 0 Keratin type II cytoskeletal 1 tail RabGAP-TBC PF00566.18 KEZ46875.1 - 4.9e-14 52.5 0.0 9.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.16 KEZ46876.1 - 1e-45 156.2 39.8 1e-45 156.2 39.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KEZ46876.1 - 2e-12 46.7 6.9 2e-12 46.7 6.9 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter D-ser_dehydrat PF14031.6 KEZ46877.1 - 4.2e-25 88.2 0.0 9.3e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KEZ46877.1 - 4.7e-11 42.7 0.0 1.4e-10 41.2 0.0 1.6 1 1 1 2 2 2 1 Alanine racemase, N-terminal domain NPCBM_assoc PF10633.9 KEZ46878.1 - 0.075 13.3 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase MG2 PF01835.19 KEZ46878.1 - 0.11 13.0 0.0 4.1 7.9 0.0 2.5 2 0 0 2 2 2 0 MG2 domain zf-C2H2 PF00096.26 KEZ46879.1 - 2.2e-06 27.8 19.0 1.8e-05 24.9 3.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KEZ46879.1 - 3.2e-05 24.2 7.3 7e-05 23.1 4.2 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KEZ46879.1 - 4.4e-05 24.0 12.3 4.5e-05 23.9 2.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KEZ46879.1 - 0.00067 19.9 1.1 0.00067 19.9 1.1 2.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KEZ46879.1 - 0.023 15.0 4.3 0.07 13.4 4.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KEZ46879.1 - 0.031 14.3 2.3 0.031 14.3 2.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 KEZ46879.1 - 0.072 13.7 8.4 0.15 12.7 0.7 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 KEZ46879.1 - 0.28 11.2 1.8 0.58 10.1 1.8 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-met PF12874.7 KEZ46879.1 - 0.3 11.6 5.9 0.14 12.6 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KEZ46879.1 - 0.72 10.0 4.2 2.1 8.5 4.3 1.6 1 1 0 1 1 1 0 Aberrant zinc-finger zf-TRAF PF02176.18 KEZ46879.1 - 0.74 10.5 8.1 0.12 13.0 3.8 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 KEZ46879.1 - 1.5 9.2 9.3 1 9.8 6.2 2.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF1295 PF06966.12 KEZ46880.1 - 1.4e-35 122.9 7.5 1.7e-35 122.7 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Hydrolase_6 PF13344.6 KEZ46881.1 - 2.8e-26 91.6 0.0 4.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KEZ46881.1 - 3.5e-14 52.6 0.0 6.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KEZ46881.1 - 7e-11 42.8 0.0 1.6e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KEZ46881.1 - 0.011 15.8 0.1 0.12 12.4 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4149 PF13664.6 KEZ46882.1 - 4.4e-27 94.4 3.1 4.4e-27 94.4 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KEZ46882.1 - 0.0049 17.2 0.5 0.007 16.7 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DnaJ PF00226.31 KEZ46883.1 - 8.2e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KEZ46883.1 - 0.00012 22.1 0.0 0.00015 21.8 0.0 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.6 KEZ46883.1 - 0.0046 16.5 1.1 0.0046 16.5 1.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) DUF4538 PF15061.6 KEZ46883.1 - 0.18 11.6 0.1 0.38 10.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Rnk_N PF14760.6 KEZ46884.1 - 0.31 11.6 2.6 0.73 10.4 2.6 1.5 1 0 0 1 1 1 0 Rnk N-terminus Ku_PK_bind PF08785.11 KEZ46885.1 - 3.5e-33 114.3 0.0 9.1e-33 113.0 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 KEZ46885.1 - 2.7e-27 95.8 0.0 4.6e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KEZ46885.1 - 8.9e-11 42.0 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KEZ46885.1 - 0.0018 18.6 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L24e PF01246.20 KEZ46886.1 - 3.9e-31 107.1 7.8 6.5e-31 106.4 5.5 2.2 2 0 0 2 2 2 1 Ribosomal protein L24e Bac_rhamnosid PF05592.11 KEZ46886.1 - 0.081 12.9 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain DUF4472 PF14739.6 KEZ46886.1 - 0.28 11.9 3.8 10 6.9 3.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF3602 PF12223.8 KEZ46887.1 - 4.8e-15 55.9 21.0 3.9e-10 40.2 1.7 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) zf-C2H2 PF00096.26 KEZ46888.1 - 0.013 15.9 3.3 0.042 14.3 3.3 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ46888.1 - 2.1 9.4 3.9 6.9 7.8 3.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Bactofilin PF04519.13 KEZ46890.1 - 3.6e-11 43.2 4.7 4.9e-06 26.7 0.7 2.1 1 1 1 2 2 2 2 Polymer-forming cytoskeletal FapA PF03961.13 KEZ46890.1 - 5.3e-09 35.2 0.8 2.4e-05 23.1 0.3 2.1 1 1 1 2 2 2 2 Flagellar Assembly Protein A MinC_C PF03775.16 KEZ46890.1 - 3.5e-05 23.7 2.5 0.0033 17.4 0.6 2.4 1 1 1 2 2 2 2 Septum formation inhibitor MinC, C-terminal domain DUF748 PF05359.11 KEZ46890.1 - 0.00032 20.9 0.0 0.31 11.2 0.0 2.5 1 1 0 2 2 2 2 Domain of Unknown Function (DUF748) PHD PF00628.29 KEZ46891.1 - 7.3e-06 25.8 6.7 1.3e-05 25.0 6.7 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KEZ46891.1 - 0.0096 16.5 1.9 0.022 15.4 0.0 2.5 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KEZ46891.1 - 0.16 12.3 1.5 0.37 11.1 1.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain DPM2 PF07297.12 KEZ46893.1 - 6.4e-34 116.1 3.0 7.3e-34 115.9 3.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KEZ46893.1 - 2.3e-05 24.3 0.9 2.5e-05 24.1 0.9 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 KEZ46893.1 - 0.0031 17.5 3.4 0.0036 17.3 3.4 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4013 PF13197.6 KEZ46893.1 - 0.0071 16.2 4.1 0.0092 15.8 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) LapA_dom PF06305.11 KEZ46893.1 - 0.012 15.4 0.4 0.012 15.4 0.4 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4229 PF14012.6 KEZ46893.1 - 0.017 15.2 8.1 0.15 12.2 8.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) Dus PF01207.17 KEZ46894.1 - 5.2e-60 203.1 0.0 8.4e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF2188 PF09954.9 KEZ46894.1 - 0.23 11.6 2.1 20 5.4 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Cwf_Cwc_15 PF04889.12 KEZ46895.1 - 4 7.1 7.7 3.3 7.4 5.5 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DotU PF09850.9 KEZ46896.1 - 0.074 12.8 0.3 5.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion system protein DotU Carb_anhydrase PF00194.21 KEZ46898.1 - 3.4e-32 112.0 0.0 6.2e-32 111.1 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AAA PF00004.29 KEZ46899.1 - 2e-47 160.9 0.0 7.1e-42 143.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KEZ46899.1 - 1.9e-08 34.0 0.0 8.4e-08 31.9 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KEZ46899.1 - 5.4e-08 33.4 4.2 0.00013 22.4 0.2 3.6 3 1 0 3 3 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KEZ46899.1 - 8.1e-07 28.9 0.0 3.9e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KEZ46899.1 - 3.8e-06 27.1 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KEZ46899.1 - 0.00063 20.0 0.2 0.03 14.6 0.2 3.2 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KEZ46899.1 - 0.0009 19.6 0.0 0.0029 17.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KEZ46899.1 - 0.00095 19.2 0.0 0.0046 17.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KEZ46899.1 - 0.0011 19.1 0.5 0.047 13.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KEZ46899.1 - 0.0086 16.6 0.8 0.06 13.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 KEZ46899.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 KEZ46899.1 - 0.012 15.4 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KEZ46899.1 - 0.015 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KEZ46899.1 - 0.02 15.4 0.0 0.11 13.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 KEZ46899.1 - 0.024 14.7 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KEZ46899.1 - 0.032 14.3 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Latarcin PF10279.9 KEZ46899.1 - 0.035 14.5 0.6 0.035 14.5 0.6 2.9 2 1 0 2 2 1 0 Latarcin precursor AAA_3 PF07726.11 KEZ46899.1 - 0.038 13.9 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 KEZ46899.1 - 0.04 14.0 0.1 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.21 KEZ46899.1 - 0.042 13.2 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KEZ46899.1 - 0.047 13.4 0.0 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.6 KEZ46899.1 - 0.05 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 KEZ46899.1 - 0.097 12.5 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 KEZ46899.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KEZ46899.1 - 0.12 12.2 0.0 0.42 10.5 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 KEZ46899.1 - 0.31 10.8 0.0 0.31 10.8 0.0 4.1 2 1 0 2 2 1 0 AAA domain Molybdopterin_N PF18364.1 KEZ46900.1 - 0.0067 16.4 0.2 0.013 15.6 0.2 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase N-terminal domain Cellulase PF00150.18 KEZ46900.1 - 0.091 12.2 0.0 0.1 12.0 0.0 1.0 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 KEZ46901.1 - 1.7e-26 93.1 0.0 3.9e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46901.1 - 1.6e-08 34.1 0.0 1.2e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KEZ46901.1 - 0.00052 18.9 0.0 0.00077 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pox_P35 PF03213.14 KEZ46901.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein DSBA PF01323.20 KEZ46902.1 - 7.3e-21 74.8 0.0 5e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain BCNT PF07572.12 KEZ46903.1 - 3.3e-25 88.0 0.8 7e-25 86.9 0.8 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development SURF2 PF05477.11 KEZ46903.1 - 9.3 5.9 8.3 17 5.0 8.3 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SNF2_N PF00176.23 KEZ46904.1 - 1.3e-72 244.4 0.5 1.3e-72 244.4 0.5 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KEZ46904.1 - 1.1e-21 77.2 4.2 1.4e-18 67.2 0.0 4.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KEZ46904.1 - 8.9e-19 67.4 0.0 2.6e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KEZ46904.1 - 1.4e-16 60.6 13.1 1.4e-16 60.6 13.1 6.0 6 1 0 6 6 6 1 HSA SnAC PF14619.6 KEZ46904.1 - 1.6e-14 54.3 0.4 1.6e-14 54.3 0.4 4.5 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 KEZ46904.1 - 3.1e-11 42.8 4.4 8.6e-11 41.4 4.4 1.9 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 KEZ46904.1 - 3.3e-09 37.0 0.0 3.3e-09 37.0 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4602 PF15375.6 KEZ46905.1 - 0.00031 21.1 6.4 0.0015 18.9 5.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) STE PF02200.16 KEZ46906.1 - 4.8e-56 187.9 0.0 7.8e-56 187.2 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KEZ46906.1 - 0.00098 19.4 4.2 0.0024 18.2 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ46906.1 - 0.041 14.7 2.4 0.096 13.6 2.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Perilipin PF03036.16 KEZ46907.1 - 0.0012 18.0 0.1 0.0022 17.1 0.0 1.4 1 1 0 1 1 1 1 Perilipin family Vault_2 PF17794.1 KEZ46907.1 - 0.0054 17.1 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 Major Vault Protein repeat domain Pirin PF02678.16 KEZ46908.1 - 6.9e-30 103.2 0.0 1.2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KEZ46908.1 - 6.3e-27 94.0 0.0 7.7e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KEZ46908.1 - 3.4e-07 29.9 2.9 6e-05 22.7 0.4 2.5 2 0 0 2 2 2 2 Cupin domain CFEM PF05730.11 KEZ46909.1 - 1.9e-13 50.3 4.4 3.5e-13 49.4 4.4 1.4 1 0 0 1 1 1 1 CFEM domain SOG2 PF10428.9 KEZ46909.1 - 0.31 10.2 5.3 0.38 9.9 5.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Ribonuc_red_lgC PF02867.15 KEZ46910.1 - 2.2e-194 646.9 0.0 2.7e-194 646.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KEZ46910.1 - 4.2e-24 84.4 0.0 9.9e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KEZ46910.1 - 3.7e-17 62.7 0.0 8.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain TatD_DNase PF01026.21 KEZ46911.1 - 1.9e-46 158.6 0.0 2.6e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase bZIP_2 PF07716.15 KEZ46912.1 - 8.9e-13 48.1 11.5 1.8e-12 47.1 11.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KEZ46912.1 - 0.0049 16.9 10.7 0.009 16.1 10.1 1.7 1 1 1 2 2 2 2 bZIP transcription factor XhlA PF10779.9 KEZ46912.1 - 0.0061 16.7 3.3 0.012 15.8 3.3 1.5 1 0 0 1 1 1 1 Haemolysin XhlA TSC22 PF01166.18 KEZ46912.1 - 0.22 11.8 0.3 0.22 11.8 0.3 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family LCD1 PF09798.9 KEZ46912.1 - 0.99 7.8 8.2 1.3 7.4 8.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Pkinase PF00069.25 KEZ46913.1 - 5.8e-65 219.3 0.0 8.8e-65 218.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KEZ46913.1 - 8.8e-30 103.8 0.0 8.9e-28 97.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase SWIB PF02201.18 KEZ46913.1 - 6.7e-20 70.8 0.0 1.9e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Kinase-like PF14531.6 KEZ46913.1 - 0.00059 19.2 0.3 0.46 9.8 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KEZ46913.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KEZ46913.1 - 0.0066 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KEZ46913.1 - 0.048 13.6 0.1 0.048 13.6 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Med3 PF11593.8 KEZ46913.1 - 0.15 11.2 4.0 0.31 10.2 4.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FTA2 PF13095.6 KEZ46913.1 - 0.22 11.1 0.3 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Mo25 PF08569.11 KEZ46914.1 - 2.8e-125 418.0 0.1 3.2e-125 417.9 0.1 1.0 1 0 0 1 1 1 1 Mo25-like Sfi1 PF08457.10 KEZ46915.1 - 2.7e-39 135.2 54.0 3.3e-23 82.1 28.8 3.1 1 1 2 3 3 3 3 Sfi1 spindle body protein Rav1p_C PF12234.8 KEZ46916.1 - 3.9e-269 894.5 0.0 1.4e-268 892.6 0.0 1.7 2 0 0 2 2 2 1 RAVE protein 1 C terminal OPT PF03169.15 KEZ46917.1 - 7.4e-123 411.3 21.4 8.6e-123 411.1 21.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Uso1_p115_head PF04869.14 KEZ46918.1 - 1.5e-110 369.2 0.0 4.6e-110 367.6 0.0 1.8 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KEZ46918.1 - 7.4e-17 61.9 21.0 7.4e-17 61.9 21.0 4.5 2 1 2 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Rab5-bind PF09311.11 KEZ46918.1 - 3.8e-06 26.5 24.5 3.8e-06 26.5 24.5 2.4 2 0 0 2 2 2 1 Rabaptin-like protein Methyltransf_11 PF08241.12 KEZ46918.1 - 7.1e-05 23.4 0.0 0.00025 21.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KEZ46918.1 - 0.0043 16.5 0.0 0.0095 15.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Arm_vescicular PF18770.1 KEZ46918.1 - 0.049 13.6 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor UPF0020 PF01170.18 KEZ46918.1 - 0.11 12.2 1.5 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 KEZ46918.1 - 0.13 12.2 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain CHD5 PF04420.14 KEZ46918.1 - 0.21 11.5 1.8 0.6 10.0 0.1 2.6 2 0 0 2 2 2 0 CHD5-like protein Filament PF00038.21 KEZ46918.1 - 2.6 7.5 42.3 0.52 9.9 5.0 3.0 2 1 1 3 3 3 0 Intermediate filament protein DUF4704 PF15787.5 KEZ46918.1 - 6.2 6.0 8.2 1.8 7.7 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4704) XRN_M PF17846.1 KEZ46919.1 - 5.9e-136 453.9 0.0 2.9e-135 451.6 0.0 1.9 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KEZ46919.1 - 7.3e-99 330.1 0.0 2e-98 328.6 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_3 PF13917.6 KEZ46919.1 - 0.022 14.7 4.6 0.048 13.6 4.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KEZ46919.1 - 0.2 11.5 2.3 0.49 10.3 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RasGAP PF00616.19 KEZ46920.1 - 5.8e-22 78.4 0.0 1.2e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Aldedh PF00171.22 KEZ46921.1 - 3.4e-130 434.6 0.1 2.7e-114 382.2 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 KEZ46921.1 - 0.00012 21.3 0.0 0.0002 20.5 0.0 1.3 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Fungal_trans PF04082.18 KEZ46922.1 - 5.7e-06 25.6 0.4 1.8e-05 23.9 0.1 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain ADH_N PF08240.12 KEZ46923.1 - 1.8e-22 79.3 2.1 3e-22 78.5 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KEZ46923.1 - 6.5e-21 74.7 0.2 1.1e-20 73.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4730 PF15873.5 KEZ46923.1 - 0.14 12.5 0.4 0.14 12.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4730) ADH_zinc_N_2 PF13602.6 KEZ46923.1 - 0.15 13.1 0.1 0.34 12.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase FAD_binding_4 PF01565.23 KEZ46924.1 - 2.5e-26 92.1 0.0 4.5e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KEZ46924.1 - 2.5e-16 60.1 0.0 3.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain SKICH PF17751.1 KEZ46924.1 - 0.19 12.3 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 SKICH domain Tannase PF07519.11 KEZ46925.1 - 2.6e-98 330.0 0.7 2.9e-98 329.8 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KEZ46925.1 - 7.3e-05 22.3 0.1 0.011 15.3 0.2 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KEZ46925.1 - 0.0026 17.5 0.6 0.012 15.3 0.4 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KEZ46925.1 - 0.0048 16.2 0.0 0.1 11.8 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Methyltransf_12 PF08242.12 KEZ46926.1 - 5e-18 65.7 0.3 2.4e-17 63.5 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46926.1 - 2.2e-16 60.0 0.0 8.6e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46926.1 - 2.7e-12 47.2 0.0 7.3e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ46926.1 - 3.5e-11 43.2 0.0 6.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46926.1 - 3.5e-11 43.6 0.0 8.1e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ46926.1 - 9.3e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KEZ46926.1 - 0.0021 17.8 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 KEZ46926.1 - 0.031 14.0 0.1 0.18 11.5 0.0 2.2 2 1 0 2 2 2 0 Lysine methyltransferase Methyltransf_24 PF13578.6 KEZ46926.1 - 0.059 14.4 0.0 0.22 12.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 KEZ46926.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 KEZ46926.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 KEZ46926.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Cnl2_NKP2 PF09447.10 KEZ46926.1 - 0.16 12.1 0.1 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Methyltransf_33 PF10017.9 KEZ46926.1 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Hydantoinase_B PF02538.14 KEZ46927.1 - 4.2e-197 655.6 0.3 7.5e-197 654.8 0.2 1.5 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KEZ46927.1 - 1.7e-103 345.9 0.2 7.3e-103 343.8 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KEZ46927.1 - 2.6e-47 160.8 0.0 5.8e-45 153.2 0.0 3.2 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 KEZ46928.1 - 6.7e-33 114.1 21.8 1e-32 113.5 21.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KEZ46928.1 - 4e-06 26.9 6.8 6.5e-06 26.2 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_holin_5_2 PF16079.5 KEZ46928.1 - 0.13 12.6 7.3 3 8.2 0.7 3.2 2 2 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V bZIP_1 PF00170.21 KEZ46928.1 - 1.1 9.4 2.7 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 bZIP transcription factor Methyltransf_23 PF13489.6 KEZ46929.1 - 1.7e-09 37.7 0.0 5.9e-09 36.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46929.1 - 1.2e-07 32.3 0.0 2.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46929.1 - 9.2e-07 28.8 0.0 2.7e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 KEZ46929.1 - 2.2e-06 27.9 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KEZ46929.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KEZ46929.1 - 0.0003 20.3 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KEZ46929.1 - 0.00036 21.2 0.0 0.00072 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KEZ46929.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 KEZ46929.1 - 0.0017 19.0 0.0 0.0037 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KEZ46929.1 - 0.0052 16.1 0.0 0.22 10.8 0.0 2.1 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KEZ46929.1 - 0.007 15.7 0.0 0.033 13.5 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KEZ46929.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 KEZ46929.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF938) F-box PF00646.33 KEZ46930.1 - 0.26 11.2 2.6 0.39 10.7 0.0 2.5 3 0 0 3 3 3 0 F-box domain Cyt_bd_oxida_I PF01654.17 KEZ46931.1 - 0.026 13.1 0.5 0.049 12.2 0.4 1.5 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I SesA PF17107.5 KEZ46932.1 - 0.00098 19.3 0.1 0.0018 18.4 0.1 1.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases K-box PF01486.17 KEZ46932.1 - 0.061 13.5 1.5 0.11 12.7 1.5 1.4 1 0 0 1 1 1 0 K-box region Zn_clus PF00172.18 KEZ46933.1 - 2e-08 34.2 8.1 3.6e-08 33.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 KEZ46934.1 - 3.7e-05 23.9 0.1 0.00052 20.2 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SLAC1 PF03595.17 KEZ46935.1 - 1.5e-37 129.6 21.8 1.8e-37 129.3 21.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TGS PF02824.21 KEZ46935.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 TGS domain Glycophorin_A PF01102.18 KEZ46935.1 - 0.17 12.1 0.6 0.3 11.3 0.6 1.4 1 0 0 1 1 1 0 Glycophorin A Methyltransf_23 PF13489.6 KEZ46936.1 - 1.7e-19 70.3 0.0 2.6e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KEZ46936.1 - 9.4e-15 55.1 0.0 2.4e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KEZ46936.1 - 1.8e-11 44.5 0.0 3.6e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KEZ46936.1 - 8.9e-11 41.8 0.0 1.5e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KEZ46936.1 - 3.4e-09 37.3 0.0 1.1e-08 35.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ46936.1 - 1.5e-06 27.7 0.0 4.1e-05 23.0 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KEZ46936.1 - 2.6e-05 24.4 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KEZ46936.1 - 0.00032 20.2 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KEZ46936.1 - 0.00038 20.1 0.0 0.00079 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KEZ46936.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KEZ46936.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KEZ46936.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 KEZ46936.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase P22_portal PF16510.5 KEZ46936.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein TauD PF02668.16 KEZ46937.1 - 2.1e-32 113.0 0.1 3e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease_2 PF13520.6 KEZ46938.1 - 7.4e-72 242.5 35.2 9.4e-72 242.1 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KEZ46938.1 - 1.6e-18 66.6 32.7 2.5e-18 65.9 32.7 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3530 PF12048.8 KEZ46939.1 - 6.9 6.0 9.0 8.3 5.7 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Polysacc_deac_1 PF01522.21 KEZ46940.1 - 2.3e-32 111.5 0.0 3.4e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KEZ46940.1 - 2.9e-05 23.4 0.1 8.7e-05 21.9 0.0 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 Chitin_bind_1 PF00187.19 KEZ46940.1 - 0.0014 19.1 16.9 0.0026 18.2 16.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein zf-H2C2_2 PF13465.6 KEZ46942.1 - 2.6e-15 56.0 17.5 1.5e-09 37.9 0.7 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KEZ46942.1 - 8.8e-15 54.2 14.8 6.9e-05 23.1 0.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KEZ46942.1 - 9.1e-07 29.2 16.1 0.018 15.8 0.2 4.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KEZ46942.1 - 0.0025 18.1 6.5 0.065 13.5 0.5 3.7 2 1 2 4 4 4 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 KEZ46942.1 - 0.0086 16.7 3.8 2 9.1 0.0 3.6 3 1 0 3 3 3 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 KEZ46942.1 - 0.0099 16.0 1.6 3.5 7.7 0.2 2.6 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KEZ46942.1 - 0.031 14.3 7.0 0.66 10.0 0.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 KEZ46942.1 - 0.055 13.9 0.1 0.055 13.9 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type GFO_IDH_MocA PF01408.22 KEZ46943.1 - 2.9e-21 76.5 0.2 4.7e-21 75.8 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 KEZ46943.1 - 0.048 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 KEZ46944.1 - 3e-55 187.7 0.1 3.8e-55 187.4 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KEZ46944.1 - 5.4e-36 124.3 0.1 9.3e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KEZ46944.1 - 2.1e-06 27.2 0.1 0.012 14.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KEZ46944.1 - 0.00062 18.9 0.9 0.0013 17.8 0.5 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KEZ46944.1 - 0.00062 19.4 3.1 0.0046 16.6 3.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KEZ46944.1 - 0.0046 17.1 0.6 0.013 15.7 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ46944.1 - 0.025 13.8 0.8 1.2 8.3 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HHH_5 PF14520.6 KEZ46944.1 - 0.035 14.7 0.7 0.092 13.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain HI0933_like PF03486.14 KEZ46944.1 - 0.11 11.2 0.4 0.23 10.1 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KEZ46944.1 - 0.12 11.6 0.4 0.26 10.5 0.4 1.5 1 0 0 1 1 1 0 Thi4 family YitT_membrane PF02588.15 KEZ46944.1 - 0.26 10.6 1.6 0.48 9.8 1.6 1.4 1 0 0 1 1 1 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Abhydrolase_3 PF07859.13 KEZ46945.1 - 5.5e-48 163.6 0.1 8.7e-48 163.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KEZ46945.1 - 3.7e-08 32.7 0.1 1e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Fungal_trans PF04082.18 KEZ46946.1 - 7.3e-12 44.9 0.6 1.7e-11 43.7 0.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KEZ46946.1 - 2.1e-05 24.5 11.0 4.6e-05 23.5 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain U62_UL91 PF17442.2 KEZ46946.1 - 0.11 12.5 0.9 0.82 9.7 0.0 2.6 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins FMO-like PF00743.19 KEZ46947.1 - 1.1e-20 73.6 0.5 1.4e-17 63.3 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KEZ46947.1 - 1.2e-11 44.7 0.0 3.3e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KEZ46947.1 - 7.1e-09 35.3 0.0 9e-07 28.4 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KEZ46947.1 - 2.2e-06 27.0 0.0 0.00023 20.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KEZ46947.1 - 0.00034 19.9 0.0 0.0011 18.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KEZ46947.1 - 0.00088 19.0 0.0 0.56 9.7 0.0 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KEZ46947.1 - 0.0031 17.5 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KEZ46947.1 - 0.13 12.9 0.0 1 10.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pericardin_rpt PF07054.11 KEZ46947.1 - 5.2 7.3 6.2 17 5.6 6.3 1.8 1 1 0 1 1 1 0 Pericardin like repeat Defensin_2 PF01097.18 KEZ46948.1 - 3.6e-05 23.6 8.9 5.1e-05 23.1 8.9 1.3 1 0 0 1 1 1 1 Arthropod defensin Toxin_3 PF00537.18 KEZ46948.1 - 0.05 13.8 6.0 0.061 13.5 6.0 1.1 1 0 0 1 1 1 0 Scorpion toxin-like domain AHSA1 PF08327.11 KEZ46949.1 - 0.15 12.3 0.0 0.92 9.7 0.0 2.0 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein PIG-L PF02585.17 KEZ46950.1 - 2e-25 89.9 0.0 3.4e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HNH_2 PF13391.6 KEZ46951.1 - 6.4e-05 23.0 0.2 0.00018 21.6 0.2 1.8 1 1 0 1 1 1 1 HNH endonuclease CDH-cyt PF16010.5 KEZ46952.1 - 8.5e-60 201.6 0.1 1e-59 201.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase LysM PF01476.20 KEZ46952.1 - 2.5e-08 33.8 0.0 7.6e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 LysM domain DOMON PF03351.17 KEZ46952.1 - 0.0057 16.9 0.0 0.0092 16.2 0.0 1.2 1 0 0 1 1 1 1 DOMON domain Methyltransf_11 PF08241.12 KEZ46953.1 - 0.013 16.2 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KEZ46953.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KEZ46953.1 - 0.029 13.7 0.0 0.69 9.2 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Scedosporium_apiospermum-ScApio1.0/GCA_000732125.1_ScApio1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Scedosporium_apiospermum-ScApio1.0/GCA_000732125.1_ScApio1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Scedosporium_apiospermum-ScApio1.0/GCA_000732125.1_ScApio1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Scedosporium_apiospermum-ScApio1.0/GCA_000732125.1_ScApio1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 05:14:14 2019 # [ok]