# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Late_protein_L2 PF00513.13 KEZ38579.1 - 0.0083 15.0 1.7 0.011 14.5 1.2 1.1 1 0 0 1 1 1 1 Late Protein L2 Aminotran_5 PF00266.14 KEZ38580.1 - 3.8e-92 308.9 0.0 4.6e-92 308.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEZ38580.1 - 1.1e-08 34.6 0.0 1.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KEZ38580.1 - 1.8e-05 23.9 0.0 0.00012 21.3 0.0 2.2 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KEZ38580.1 - 0.013 14.0 0.0 0.018 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 KEZ38580.1 - 0.028 12.7 0.0 0.042 12.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-C4 PF00105.13 KEZ38580.1 - 0.12 12.6 0.3 0.29 11.4 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) BAR PF03114.13 KEZ38581.1 - 2.2e-60 204.0 5.7 2.9e-60 203.6 3.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KEZ38581.1 - 1.3e-14 53.2 0.1 2.6e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ38581.1 - 4.9e-13 48.4 0.0 9.6e-13 47.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEZ38581.1 - 3.6e-09 35.9 0.0 1e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain APG6 PF04111.7 KEZ38581.1 - 0.044 12.8 6.7 0.1 11.6 1.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 KEZ38581.1 - 0.48 9.4 2.6 0.36 9.8 0.1 1.9 1 1 1 2 2 2 0 TMPIT-like protein F-box-like PF12937.2 KEZ38582.1 - 0.00075 19.1 0.1 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ38582.1 - 0.0083 15.7 0.0 0.0083 15.7 0.0 2.2 2 0 0 2 2 2 1 F-box domain ADIP PF11559.3 KEZ38583.1 - 1.7e-39 135.1 6.7 6.8e-39 133.1 4.7 2.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.6 KEZ38583.1 - 2.7 8.4 13.5 0.54 10.7 3.5 3.4 3 1 0 3 3 3 0 Syntaxin 6, N-terminal TPR_11 PF13414.1 KEZ38584.1 - 0.029 14.0 2.1 0.25 11.0 1.5 2.1 1 1 0 1 1 1 0 TPR repeat DUF4398 PF14346.1 KEZ38584.1 - 0.032 14.2 0.5 0.061 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) TPR_1 PF00515.23 KEZ38584.1 - 0.12 12.0 1.4 1 9.0 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ38584.1 - 0.39 11.4 2.6 2.3 9.0 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.2 KEZ38584.1 - 0.82 9.3 2.8 8.8 6.0 0.0 4.0 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 KEZ38585.1 - 7.5e-55 185.8 0.0 1.1e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ38585.1 - 6.1e-19 68.1 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ38585.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pex24p PF06398.6 KEZ38586.1 - 8.8e-79 264.8 0.0 2.1e-78 263.6 0.0 1.5 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin Metal_resist PF13801.1 KEZ38586.1 - 0.083 12.8 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Heavy-metal resistance SKG6 PF08693.5 KEZ38587.1 - 0.13 11.6 0.3 0.25 10.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GST_C_3 PF14497.1 KEZ38588.1 - 5.1e-05 23.6 0.1 8.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 KEZ38588.1 - 0.0003 20.9 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF2731 PF10806.3 KEZ38588.1 - 0.0085 16.3 0.1 0.019 15.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) SPRY PF00622.23 KEZ38589.1 - 1.8e-28 99.1 1.3 3.1e-28 98.3 0.9 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 KEZ38589.1 - 5.7e-26 90.9 0.0 8.3e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KEZ38589.1 - 1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 LisH DUF4376 PF14301.1 KEZ38589.1 - 0.72 10.0 6.0 1.1 9.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4376) INO80_Ies4 PF08193.6 KEZ38590.1 - 1e-50 172.7 23.5 1e-50 172.7 16.3 1.7 1 1 0 1 1 1 1 INO80 complex subunit Ies4 AA_permease_2 PF13520.1 KEZ38591.1 - 5.9e-54 183.2 51.1 1.6e-53 181.8 35.5 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ38591.1 - 2.8e-24 85.3 53.1 6.3e-23 80.8 36.8 2.0 1 1 0 1 1 1 1 Amino acid permease DUF4191 PF13829.1 KEZ38591.1 - 1.7 7.6 5.6 2.1 7.3 1.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) peroxidase PF00141.18 KEZ38592.1 - 1.8e-84 282.8 0.0 9.8e-45 152.8 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Aldedh PF00171.17 KEZ38593.1 - 2.7e-188 626.0 0.0 3e-188 625.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cu_amine_oxid PF01179.15 KEZ38594.1 - 1e-167 558.1 0.1 1.2e-167 557.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KEZ38594.1 - 7.3e-18 64.5 0.1 1.5e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KEZ38594.1 - 2e-15 56.6 0.2 4.1e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Fungal_trans_2 PF11951.3 KEZ38595.1 - 1.8e-12 46.5 0.7 1.5e-07 30.4 0.1 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF2306 PF10067.4 KEZ38596.1 - 1.1e-10 41.5 10.2 1.1e-10 41.5 7.0 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) IncA PF04156.9 KEZ38596.1 - 0.66 9.5 2.1 2.5 7.6 0.8 2.1 2 0 0 2 2 2 0 IncA protein Amidohydro_2 PF04909.9 KEZ38597.1 - 9.1e-30 104.1 0.6 1.2e-29 103.7 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Dak1_2 PF13684.1 KEZ38597.1 - 0.25 10.2 0.2 0.39 9.5 0.2 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family IDO PF01231.13 KEZ38598.1 - 2.8e-42 144.6 0.0 3.8e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase TPMT PF05724.6 KEZ38599.1 - 3.6e-31 108.3 0.0 9.6e-31 106.9 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KEZ38599.1 - 6.9e-10 39.4 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ38599.1 - 1.6e-06 27.9 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ38599.1 - 2.1e-06 27.3 0.0 1.4e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ38599.1 - 3.7e-05 24.1 0.0 8.7e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ38599.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KEZ38599.1 - 0.0031 16.6 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 KEZ38599.1 - 0.0047 17.3 0.0 0.013 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.13 KEZ38599.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 KEZ38599.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 KEZ38599.1 - 0.084 12.8 0.0 0.24 11.4 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain Dicty_REP PF05086.7 KEZ38599.1 - 0.31 8.7 2.9 0.4 8.3 2.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Chitin_synth_1 PF01644.12 KEZ38600.1 - 5.9e-70 234.2 0.0 8.6e-70 233.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KEZ38600.1 - 2e-27 95.8 0.1 3.4e-22 78.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KEZ38600.1 - 6.2e-27 93.0 0.0 1.7e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KEZ38600.1 - 4.3e-11 42.8 2.2 6e-11 42.4 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ38600.1 - 3.8e-08 33.4 0.0 9.5e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF3737 PF12541.3 KEZ38601.1 - 0.042 12.8 0.5 0.077 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3737) Syndecan PF01034.15 KEZ38601.1 - 0.13 11.8 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain YrhK PF14145.1 KEZ38602.1 - 2.6e-09 36.6 17.8 0.00048 19.7 0.3 5.0 4 1 1 5 5 5 3 YrhK-like protein DUF2583 PF10762.4 KEZ38602.1 - 2.4 8.3 6.0 1.4 9.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) CD20 PF04103.10 KEZ38602.1 - 6 6.7 9.0 16 5.4 0.6 2.6 2 0 0 2 2 2 0 CD20-like family Mcp5_PH PF12814.2 KEZ38603.1 - 1.7e-47 160.3 0.1 3.6e-47 159.2 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KEZ38603.1 - 0.0069 16.1 10.2 0.0069 16.1 7.1 2.4 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 KEZ38603.1 - 1.6 8.6 18.5 3.8 7.4 12.9 1.5 1 0 0 1 1 1 0 Fez1 TMCO5 PF14992.1 KEZ38603.1 - 4.3 6.3 14.4 6.7 5.7 10.0 1.2 1 0 0 1 1 1 0 TMCO5 family IncA PF04156.9 KEZ38603.1 - 4.8 6.7 23.0 2.3 7.7 4.9 2.4 1 1 1 2 2 2 0 IncA protein UQ_con PF00179.21 KEZ38604.1 - 8.7e-37 125.6 0.0 1.2e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ38604.1 - 0.0077 15.9 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B eIF3_subunit PF08597.5 KEZ38604.1 - 0.039 13.5 0.6 0.039 13.5 0.4 1.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit IlvN PF07991.7 KEZ38605.1 - 1.6e-46 157.6 0.0 2.4e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KEZ38605.1 - 1.7e-46 157.7 0.0 2.5e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KEZ38605.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEZ38605.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.20 KEZ38606.1 - 2e-61 207.8 0.3 2.6e-61 207.5 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.12 KEZ38606.1 - 0.052 13.9 1.7 0.91 9.9 0.1 2.8 1 1 2 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Transglut_core PF01841.14 KEZ38606.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily DFP PF04127.10 KEZ38606.1 - 0.16 11.5 0.2 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.11 KEZ38607.1 - 4.5e-40 137.4 45.7 5.9e-40 137.0 26.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily COX14 PF14880.1 KEZ38607.1 - 0.49 10.0 2.0 1 9.0 0.0 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly CDC45 PF02724.9 KEZ38607.1 - 0.7 7.8 9.2 1 7.3 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RseC_MucC PF04246.7 KEZ38607.1 - 3 7.4 8.6 1.5 8.3 0.0 3.5 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Aldedh PF00171.17 KEZ38608.1 - 7.6e-16 57.4 5.2 6.7e-11 41.1 2.0 2.4 1 1 1 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 KEZ38608.1 - 0.056 12.3 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) BRCT PF00533.21 KEZ38609.1 - 1.9e-05 24.7 0.0 6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEZ38609.1 - 0.00014 21.6 0.4 0.00055 19.7 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain RAM PF15320.1 KEZ38609.1 - 0.2 11.9 1.3 0.48 10.7 0.9 1.7 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein AMP-binding PF00501.23 KEZ38610.1 - 3.2e-76 256.3 0.0 3.8e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ38610.1 - 1.1e-16 61.4 1.6 3.8e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 KEZ38611.1 - 1.4e-14 53.9 0.7 7.1e-14 51.5 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ38611.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N PF00107.21 KEZ38612.1 - 2.2e-26 91.9 0.2 3.8e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ38612.1 - 7.1e-22 78.6 0.3 1.5e-21 77.6 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ38612.1 - 4.3e-10 39.3 0.0 8e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain KilA-N PF04383.8 KEZ38613.1 - 0.00071 19.1 0.0 0.0087 15.6 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Flocculin_t3 PF13928.1 KEZ38614.1 - 0.83 9.8 29.4 0.09 12.9 7.0 2.7 1 1 1 2 2 2 0 Flocculin type 3 repeat DLH PF01738.13 KEZ38615.1 - 1e-17 64.1 0.0 1.7e-16 60.1 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ38615.1 - 3e-06 27.0 0.1 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Rep_fac-A_C PF08646.5 KEZ38616.1 - 4.7e-47 159.3 3.1 6.4e-45 152.4 1.9 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KEZ38616.1 - 5.4e-19 67.8 0.1 1.9e-18 66.0 0.0 2.0 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KEZ38616.1 - 3.4e-15 55.6 0.4 5.4e-11 42.1 0.0 3.9 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 KEZ38616.1 - 0.089 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 VEGF_C PF14554.1 KEZ38616.1 - 5.9 6.7 7.1 1.5 8.6 2.0 2.0 2 0 0 2 2 2 0 VEGF heparin-binding domain PCI PF01399.22 KEZ38617.1 - 0.071 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 PCI domain TPR_14 PF13428.1 KEZ38617.1 - 1.1 10.0 5.1 17 6.3 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat zf-PHD-like PF15446.1 KEZ38619.1 - 1.8e-64 216.2 13.0 1.8e-64 216.2 9.0 2.6 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KEZ38619.1 - 4.8e-56 189.7 0.0 4.8e-56 189.7 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ38619.1 - 1.2e-13 50.7 0.0 9.8e-13 47.7 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KEZ38619.1 - 2.8e-12 46.0 0.2 2.8e-12 46.0 0.1 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 KEZ38619.1 - 1.3e-06 27.9 1.7 4.3e-05 23.1 0.1 3.5 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 KEZ38619.1 - 0.00039 20.0 16.8 0.0051 16.4 7.1 3.2 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 KEZ38619.1 - 1.8 7.9 13.0 0.019 14.2 0.8 2.9 3 0 0 3 3 3 0 PHD-finger DUF1365 PF07103.6 KEZ38621.1 - 1.9e-16 59.9 0.0 3.3e-10 39.4 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1365) GFA PF04828.9 KEZ38622.1 - 9.1e-22 76.8 0.0 1.3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MBF1 PF08523.5 KEZ38623.1 - 2.2e-21 75.6 0.7 3.8e-21 74.8 0.5 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KEZ38623.1 - 6.8e-11 41.8 0.0 1.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KEZ38623.1 - 9.9e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KEZ38623.1 - 0.00022 21.3 0.0 0.00028 21.0 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 KEZ38623.1 - 0.051 12.9 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding GST_N_3 PF13417.1 KEZ38624.1 - 7.9e-14 51.6 0.3 1.7e-13 50.6 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEZ38624.1 - 2.1e-05 24.4 0.0 4.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEZ38624.1 - 0.0025 18.2 0.0 0.0041 17.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEZ38624.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MIS13 PF08202.6 KEZ38625.1 - 1.9e-57 194.6 2.1 1.9e-57 194.6 1.5 2.2 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Aft1_HRA PF11786.3 KEZ38625.1 - 3.7e-28 97.6 10.3 3.7e-28 97.6 7.1 2.9 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 KEZ38625.1 - 2.6e-20 73.2 4.5 2.6e-20 73.2 3.1 4.6 6 0 0 6 6 6 1 Aft1 HRR domain Aft1_OSA PF11785.3 KEZ38625.1 - 7.8e-17 61.5 5.0 7.8e-17 61.5 3.5 4.4 5 1 1 6 6 6 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 KEZ38625.1 - 6.6e-12 45.2 17.8 7.3e-12 45.0 5.3 3.5 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ38625.1 - 2.3e-06 27.2 8.0 2.3e-06 27.2 5.5 3.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEZ38625.1 - 0.0041 17.3 4.9 0.0041 17.3 3.4 3.2 3 0 0 3 3 3 1 bZIP Maf transcription factor Sdh5 PF03937.11 KEZ38626.1 - 6e-23 80.3 0.2 2.9e-22 78.1 0.2 1.9 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase EMP24_GP25L PF01105.19 KEZ38627.1 - 4.9e-41 140.4 0.0 5.5e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD zf-U1 PF06220.7 KEZ38628.1 - 6.9e-22 76.7 3.4 1.1e-21 76.0 2.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KEZ38628.1 - 0.024 14.7 3.3 0.049 13.7 2.3 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Amidohydro_2 PF04909.9 KEZ38629.1 - 5.4e-18 65.5 0.0 7.6e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Spt5-NGN PF03439.8 KEZ38629.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section HD PF01966.17 KEZ38630.1 - 5.2e-09 36.1 0.1 3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 HD domain SUR7 PF06687.7 KEZ38632.1 - 4.5e-28 98.2 8.9 4.5e-28 98.2 6.1 1.7 1 1 0 2 2 2 1 SUR7/PalI family Ras PF00071.17 KEZ38633.1 - 9.4e-17 60.8 0.0 2e-15 56.5 0.0 2.7 2 1 0 2 2 2 1 Ras family Miro PF08477.8 KEZ38633.1 - 4.6e-11 43.2 0.0 9.3e-10 39.0 0.0 2.5 3 0 0 3 3 3 1 Miro-like protein AAA_17 PF13207.1 KEZ38633.1 - 0.0027 18.5 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arf PF00025.16 KEZ38633.1 - 0.0092 15.2 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 KEZ38633.1 - 0.01 15.8 0.0 0.068 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KEZ38633.1 - 0.039 13.9 2.2 0.43 10.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KEZ38633.1 - 0.061 13.4 0.2 0.59 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KEZ38633.1 - 0.076 12.7 0.3 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 KEZ38633.1 - 0.097 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.24 KEZ38633.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEZ38633.1 - 0.19 11.5 0.7 0.91 9.3 0.0 2.4 3 0 0 3 3 3 0 Part of AAA domain TRP PF06011.7 KEZ38634.1 - 1e-149 498.8 34.1 1.3e-149 498.5 23.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEZ38634.1 - 5.4e-41 139.9 0.3 9.4e-41 139.1 0.2 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 KEZ38634.1 - 0.0029 17.8 0.2 0.0051 17.0 0.1 1.4 1 0 0 1 1 1 1 ML domain AIM24 PF01987.12 KEZ38635.1 - 1.7e-51 174.7 0.5 2.1e-51 174.4 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Med1 PF10744.4 KEZ38636.1 - 4.4e-38 131.0 0.0 2.2e-37 128.7 0.0 1.9 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.20 KEZ38637.1 - 4.6e-40 137.3 0.0 2.6e-39 134.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ38637.1 - 6e-23 81.2 0.0 4e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Spc97_Spc98 PF04130.8 KEZ38638.1 - 2.3e-120 402.4 0.0 3.3e-120 401.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family SAGA-Tad1 PF12767.2 KEZ38639.1 - 3.2e-52 177.7 0.0 4.3e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit cNMP_binding PF00027.24 KEZ38640.1 - 6.8e-42 141.1 0.0 1.7e-23 82.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KEZ38640.1 - 1.8e-07 30.4 0.1 3.8e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF1569 PF07606.6 KEZ38640.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) BCAS2 PF05700.6 KEZ38641.1 - 9.7e-33 113.4 0.0 1.2e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 KEZ38641.1 - 0.0021 17.7 0.6 0.003 17.2 0.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding HABP4_PAI-RBP1 PF04774.10 KEZ38642.1 - 4.9e-05 23.7 4.3 8.1e-05 23.0 3.0 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family HD-ZIP_N PF04618.7 KEZ38642.1 - 0.015 15.8 0.8 0.018 15.5 0.5 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus TPR_12 PF13424.1 KEZ38643.1 - 2.9e-11 43.1 0.4 7.6e-05 22.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ38643.1 - 8.6e-10 38.1 5.3 6.8e-05 22.4 0.2 3.3 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 KEZ38643.1 - 1.1e-06 27.9 3.7 0.0021 17.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ38643.1 - 3.5e-06 26.5 3.0 0.0014 18.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ38643.1 - 9.6e-05 21.9 0.1 0.17 11.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ38643.1 - 0.0024 17.5 2.0 0.13 12.1 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ38643.1 - 0.04 13.8 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ38643.1 - 0.069 13.8 0.8 15 6.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CytB6-F_Fe-S PF08802.5 KEZ38643.1 - 3.3 7.7 7.6 0.26 11.3 1.8 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit AMP-binding PF00501.23 KEZ38644.1 - 6.9e-82 275.0 0.0 8.8e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ38644.1 - 3.3e-12 47.1 0.0 1e-11 45.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CDC50 PF03381.10 KEZ38645.1 - 7.3e-97 323.8 0.0 8.8e-97 323.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 KEZ38646.1 - 1.1e-58 197.4 0.1 1.1e-58 197.4 0.1 2.7 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KEZ38646.1 - 9.5e-52 174.8 0.3 2.9e-51 173.2 0.2 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 KEZ38646.1 - 4.5e-22 77.8 0.1 1.2e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 KEZ38646.1 - 4.7e-22 78.5 0.0 9.2e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Cyt-b5 PF00173.23 KEZ38647.1 - 1.5e-14 53.5 0.0 1.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CMD PF02627.15 KEZ38648.1 - 2.1e-08 33.9 0.1 3.1e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Aldo_ket_red PF00248.16 KEZ38649.1 - 1.3e-09 37.3 0.0 1.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 KEZ38650.1 - 1.8e-52 176.8 1.5 2.1e-52 176.6 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 KEZ38651.1 - 3.2e-51 173.7 0.0 4.4e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator HATPase_c PF02518.21 KEZ38652.1 - 2.2e-29 101.3 0.3 7.6e-29 99.6 0.2 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEZ38652.1 - 2.4e-27 95.1 0.3 5.1e-27 94.1 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEZ38652.1 - 2.6e-13 49.7 0.0 5.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KEZ38652.1 - 0.00054 20.0 0.1 0.38 10.9 0.0 3.5 3 0 0 3 3 3 1 HAMP domain ORMDL PF04061.9 KEZ38653.1 - 7.9e-60 200.3 3.2 9.8e-60 200.0 2.2 1.1 1 0 0 1 1 1 1 ORMDL family Methyltransf_3 PF01596.12 KEZ38654.1 - 3.2e-37 127.5 0.0 5.4e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 KEZ38654.1 - 5.8e-15 55.3 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KEZ38654.1 - 1e-13 51.1 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KEZ38654.1 - 2.8e-13 50.6 0.0 3.3e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ38654.1 - 1.2e-10 41.9 0.0 2.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ38654.1 - 2.6e-08 33.9 0.0 5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ38654.1 - 5.1e-05 23.5 0.0 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ38654.1 - 0.00039 20.8 0.0 0.0018 18.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ38654.1 - 0.00042 19.7 0.0 0.00077 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEZ38654.1 - 0.00063 18.9 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEZ38654.1 - 0.0075 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KEZ38654.1 - 0.0097 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.12 KEZ38654.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase SUR7 PF06687.7 KEZ38656.1 - 3.8e-24 85.4 10.4 5.4e-24 84.9 7.2 1.3 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KEZ38656.1 - 6.9e-09 35.6 2.1 6.9e-09 35.6 1.5 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction AA_permease_2 PF13520.1 KEZ38656.1 - 0.098 11.1 9.1 0.18 10.3 6.3 1.6 1 1 0 1 1 1 0 Amino acid permease Orbi_NS3 PF01616.11 KEZ38656.1 - 0.29 10.0 4.4 0.18 10.7 0.2 2.3 2 1 1 3 3 3 0 Orbivirus NS3 Wzy_C PF04932.10 KEZ38656.1 - 2.1 8.0 7.3 0.44 10.3 2.0 1.9 2 0 0 2 2 2 0 O-Antigen ligase DUF3169 PF11368.3 KEZ38656.1 - 3.8 6.6 11.4 0.45 9.6 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) EI24 PF07264.6 KEZ38656.1 - 3.8 6.8 12.2 2.7 7.3 1.0 2.3 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) VIT1 PF01988.14 KEZ38656.1 - 4 6.8 12.9 0.039 13.4 3.6 1.5 2 0 0 2 2 2 0 VIT family ArsA_ATPase PF02374.10 KEZ38658.1 - 3.3e-112 374.4 0.0 3.8e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KEZ38658.1 - 3.3e-17 62.5 0.6 9.9e-17 60.9 0.4 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KEZ38658.1 - 2.7e-10 40.3 0.0 6.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KEZ38658.1 - 4.3e-06 26.3 0.8 0.00078 18.9 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 KEZ38658.1 - 1.1e-05 24.7 0.0 2.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 KEZ38658.1 - 0.0031 16.9 0.3 0.012 15.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 KEZ38658.1 - 0.01 14.9 0.1 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 ATPase MipZ NB-ARC PF00931.17 KEZ38658.1 - 0.021 13.7 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain YhjQ PF06564.7 KEZ38658.1 - 0.028 13.7 0.0 0.09 12.1 0.0 1.7 2 0 0 2 2 2 0 YhjQ protein AAA_18 PF13238.1 KEZ38658.1 - 0.039 14.2 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEZ38658.1 - 0.043 12.9 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 KEZ38658.1 - 0.06 12.2 0.1 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 KEZ38658.1 - 0.077 12.5 0.3 0.29 10.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KEZ38658.1 - 0.078 12.6 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 KEZ38658.1 - 0.089 12.0 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 KEZ38658.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KEZ38658.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DWNN PF08783.6 KEZ38659.1 - 1.5e-21 76.1 0.0 2.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC PF00098.18 KEZ38659.1 - 0.00057 19.6 1.8 0.00057 19.6 1.2 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 KEZ38659.1 - 0.0012 18.2 5.5 0.0045 16.4 3.8 2.0 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 KEZ38659.1 - 0.0027 17.6 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain DUF966 PF06136.8 KEZ38659.1 - 0.0029 17.0 3.0 0.0029 17.0 2.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF966) zf-RING_5 PF14634.1 KEZ38659.1 - 0.0034 17.0 5.4 0.0034 17.0 3.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-CCHC_3 PF13917.1 KEZ38659.1 - 0.048 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-RING_4 PF14570.1 KEZ38659.1 - 0.057 13.0 6.2 0.14 11.7 4.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KEZ38659.1 - 0.11 12.2 1.3 0.22 11.3 0.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KEZ38659.1 - 0.12 12.2 9.9 0.36 10.7 6.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KEZ38659.1 - 0.26 10.8 5.8 0.58 9.7 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 KEZ38659.1 - 0.26 11.3 14.9 0.026 14.5 5.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ38659.1 - 0.56 9.8 8.9 1.1 8.9 6.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ38659.1 - 1.2 9.0 11.6 0.031 14.0 3.7 1.7 2 0 0 2 2 2 0 Ring finger domain Peptidase_M20 PF01546.23 KEZ38660.1 - 6.3e-33 113.8 0.0 1.1e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEZ38660.1 - 1.7e-11 43.8 0.0 2.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.18 KEZ38661.1 - 1.4e-11 44.5 0.0 2.6e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KEZ38661.1 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.15 KEZ38661.1 - 0.034 13.7 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ODC_AZ PF02100.12 KEZ38662.1 - 6e-28 96.5 0.0 9.5e-28 95.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.16 KEZ38663.1 - 3.1e-50 170.5 0.4 1.5e-49 168.3 0.3 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KEZ38663.1 - 2.3e-26 92.4 0.0 3.6e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KEZ38663.1 - 2.9e-07 30.3 0.0 6.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KEZ38663.1 - 1.1e-05 25.0 0.1 3.2e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 KEZ38663.1 - 0.087 11.6 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) TFIIIC_sub6 PF10419.4 KEZ38664.1 - 1.2e-13 50.2 0.0 2.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit Transformer PF06495.6 KEZ38665.1 - 0.045 13.6 0.6 0.045 13.6 0.4 1.9 2 0 0 2 2 2 0 Fruit fly transformer protein Ribosomal_L7Ae PF01248.21 KEZ38666.1 - 3.7e-24 84.0 0.0 4.2e-24 83.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 KEZ38667.1 - 2e-30 105.2 0.0 2.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Peptidase_S28 PF05577.7 KEZ38668.1 - 0.059 11.9 1.7 0.085 11.4 1.2 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF3818 PF12825.2 KEZ38668.1 - 0.13 10.8 4.9 0.67 8.5 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Z1 PF10593.4 KEZ38668.1 - 1 8.5 10.4 1.2 8.3 6.2 1.8 1 1 1 2 2 2 0 Z1 domain DUF948 PF06103.6 KEZ38668.1 - 1 9.2 2.7 1.5 8.7 0.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MIF4G_like_2 PF09090.6 KEZ38668.1 - 5.6 6.0 21.1 0.99 8.5 7.2 2.6 2 1 0 2 2 2 0 MIF4G like Fib_alpha PF08702.5 KEZ38668.1 - 7.9 6.6 16.4 0.95 9.5 1.9 2.9 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family CorA PF01544.13 KEZ38668.1 - 8 5.4 13.2 0.061 12.3 0.4 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Vac7 PF12751.2 KEZ38669.1 - 1.1e-118 396.5 4.4 2.2e-118 395.5 3.1 1.5 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 PRP1_N PF06424.7 KEZ38670.1 - 2.1e-50 170.4 3.2 5.1e-50 169.2 2.2 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KEZ38670.1 - 8e-34 113.0 30.1 0.0001 22.5 0.2 14.7 5 3 10 15 15 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ38670.1 - 1.2e-29 102.3 13.2 4.6e-09 36.4 0.8 9.2 6 3 4 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ38670.1 - 3e-22 78.7 21.6 1.3e-07 32.0 0.7 9.2 8 2 2 11 11 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ38670.1 - 8.8e-16 57.3 11.2 0.0017 17.9 0.5 8.4 6 2 2 9 9 9 3 TPR repeat TPR_2 PF07719.12 KEZ38670.1 - 6.4e-14 50.6 11.2 0.18 11.8 0.0 9.8 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ38670.1 - 3.4e-11 42.4 3.5 5.5 7.4 0.0 8.9 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ38670.1 - 9e-10 37.6 0.2 0.43 10.4 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ38670.1 - 2.5e-08 33.1 1.2 0.21 11.2 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ38670.1 - 3e-07 29.7 24.7 0.0036 16.4 4.1 6.7 4 1 3 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.3 KEZ38670.1 - 5.8e-07 28.6 11.8 0.027 13.2 0.0 6.4 5 2 2 7 7 7 3 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 KEZ38670.1 - 0.00017 21.1 2.6 1.8 8.5 0.0 6.4 8 0 0 8 8 5 1 Tetratricopeptide repeat Suf PF05843.9 KEZ38670.1 - 0.00019 21.2 2.7 0.24 11.0 0.0 4.9 6 1 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 KEZ38670.1 - 0.00022 21.4 12.7 15 6.3 0.0 8.4 10 0 0 10 10 8 0 Tetratricopeptide repeat Apc3 PF12895.2 KEZ38670.1 - 0.00079 19.5 0.1 0.14 12.3 0.0 4.0 5 0 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEZ38670.1 - 0.001 18.9 11.9 0.56 10.1 0.0 6.0 7 1 0 7 7 6 2 Tetratricopeptide repeat DUF3808 PF10300.4 KEZ38670.1 - 0.0012 17.4 1.8 4.4 5.7 0.0 4.6 4 1 2 6 6 6 1 Protein of unknown function (DUF3808) TPR_9 PF13371.1 KEZ38670.1 - 0.0048 16.7 11.0 1.4 8.8 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.4 KEZ38670.1 - 0.074 12.9 25.7 0.15 12.0 1.2 5.9 5 1 1 6 6 5 0 Tetratricopeptide repeat Apolipoprotein PF01442.13 KEZ38671.1 - 0.0076 15.7 0.1 0.01 15.3 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 KEZ38671.1 - 0.058 13.7 0.5 0.12 12.7 0.4 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.1 KEZ38671.1 - 0.68 10.0 7.4 0.53 10.4 1.0 2.4 2 1 0 2 2 2 0 MT0933-like antitoxin protein MutS_III PF05192.13 KEZ38672.1 - 0.049 13.3 0.5 0.081 12.6 0.3 1.3 1 0 0 1 1 1 0 MutS domain III PP2C PF00481.16 KEZ38673.1 - 1.2e-82 277.1 0.0 1.7e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KEZ38673.1 - 0.0002 20.8 0.0 0.00044 19.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C ALAD PF00490.16 KEZ38674.1 - 6.2e-116 386.8 0.0 7.5e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DUF1179 PF06678.6 KEZ38675.1 - 0.053 13.8 1.2 1.8 8.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Amidohydro_3 PF07969.6 KEZ38676.1 - 5.8e-64 216.7 0.0 6.7e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEZ38676.1 - 0.0033 17.1 0.0 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEZ38676.1 - 0.099 12.2 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Amidohydrolase family 2Fe-2S_thioredx PF01257.14 KEZ38677.1 - 1.1e-57 193.7 0.0 1.4e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin zf-C2H2 PF00096.21 KEZ38678.1 - 1.7e-08 34.3 27.3 0.00068 19.8 4.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ38678.1 - 4.8e-08 32.7 27.1 0.0029 17.8 2.0 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ38678.1 - 0.012 15.9 23.0 0.18 12.1 2.0 5.4 5 0 0 5 5 5 0 Zinc-finger double domain DUF629 PF04780.7 KEZ38678.1 - 0.18 10.2 10.7 0.012 14.2 1.6 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF629) Nucleoporin_C PF03177.9 KEZ38680.1 - 1.6e-81 274.5 3.7 2.3e-81 274.1 2.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KEZ38680.1 - 2.5e-73 247.2 0.0 3.2e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 KEZ38681.1 - 4.4e-35 121.1 0.0 5.6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ38681.1 - 3.4e-14 52.5 0.0 4.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ38681.1 - 0.0056 16.4 0.0 0.19 11.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family EMP24_GP25L PF01105.19 KEZ38682.1 - 1.8e-51 174.4 0.0 2.1e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 KEZ38682.1 - 0.025 15.0 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Hexapep_2 PF14602.1 KEZ38683.1 - 5.4e-15 54.6 17.5 2.1e-08 33.5 3.3 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 KEZ38683.1 - 1.1e-12 46.8 19.0 5.6e-07 28.7 1.7 3.9 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 KEZ38683.1 - 2.8e-10 40.0 0.1 6.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 KEZ38683.1 - 9.1e-10 38.2 7.9 2e-09 37.2 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KEZ38684.1 - 2.8e-48 160.1 28.1 3e-10 39.5 0.1 10.8 11 0 0 11 11 11 9 WD domain, G-beta repeat PD40 PF07676.7 KEZ38684.1 - 0.005 16.4 0.4 8.4 6.1 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 KEZ38684.1 - 0.006 15.7 0.8 6.6 5.7 0.0 3.6 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Glyco_tran_28_C PF04101.11 KEZ38685.1 - 5.7e-18 65.1 0.0 2.6e-17 63.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 KEZ38685.1 - 0.048 12.2 0.0 0.096 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase MRP-S28 PF10213.4 KEZ38686.1 - 2.1e-44 150.6 0.0 3.9e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein zf-MIZ PF02891.15 KEZ38687.1 - 5.8e-08 32.1 5.4 6.2e-06 25.6 0.1 2.5 1 1 1 2 2 2 2 MIZ/SP-RING zinc finger PINIT PF14324.1 KEZ38687.1 - 0.029 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 PINIT domain SAM_2 PF07647.12 KEZ38688.1 - 2.2e-13 49.8 0.0 4.3e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 KEZ38688.1 - 4.8e-13 48.4 0.0 9.8e-13 47.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ38688.1 - 7.3e-12 44.4 0.0 1.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 KEZ38688.1 - 2.7e-08 33.9 0.0 5.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 KEZ38688.1 - 1.2e-05 24.6 0.0 2.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 KEZ38688.1 - 5.8e-05 23.3 0.1 0.00015 21.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 KEZ38688.1 - 0.0077 16.3 0.1 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 KEZ38688.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Agenet PF05641.7 KEZ38688.1 - 0.076 13.1 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Agenet domain Sulfate_transp PF00916.15 KEZ38689.1 - 0.00046 19.2 10.5 0.0036 16.3 7.3 2.5 1 1 0 1 1 1 1 Sulfate transporter family PS_Dcarbxylase PF02666.10 KEZ38690.1 - 2.4e-53 180.4 0.0 3.5e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KEZ38690.1 - 2.9e-32 110.3 0.0 1.1e-14 53.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.27 KEZ38690.1 - 0.0012 18.0 0.0 0.0038 16.4 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KEZ38690.1 - 0.004 17.2 0.1 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KEZ38690.1 - 0.016 15.0 0.5 0.083 12.8 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain LRR_6 PF13516.1 KEZ38692.1 - 0.00028 20.6 0.1 64 4.0 0.0 6.4 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.2 KEZ38692.1 - 0.0062 16.1 3.4 2.2 8.0 0.0 5.1 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KEZ38692.1 - 5.1 7.7 6.9 1.5e+02 3.3 0.0 5.5 8 0 0 8 8 8 0 Leucine rich repeat Ribosomal_L18p PF00861.17 KEZ38694.1 - 4e-42 143.1 0.0 4e-42 143.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KEZ38694.1 - 7.4e-35 119.3 5.8 7.4e-35 119.3 4.0 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 KEZ38694.1 - 0.017 15.1 1.1 0.56 10.2 0.0 2.9 3 1 0 3 3 3 0 Threonine synthase N terminus HAD_2 PF13419.1 KEZ38695.1 - 9.3e-15 55.2 0.0 1.6e-13 51.2 0.0 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KEZ38695.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Hydrolase_like PF13242.1 KEZ38695.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Coatomer_E PF04733.9 KEZ38696.1 - 6.7e-66 222.4 4.6 7.7e-66 222.2 3.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KEZ38696.1 - 4.8e-09 36.4 11.1 0.0038 17.5 0.2 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ38696.1 - 1.5e-06 28.6 3.5 0.008 16.8 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ38696.1 - 2.5e-06 27.6 11.0 0.016 15.7 0.1 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ38696.1 - 6.3e-05 22.5 1.7 0.0048 16.5 0.0 3.4 4 1 0 4 4 3 1 TPR repeat TPR_5 PF12688.2 KEZ38696.1 - 9.7e-05 22.3 1.4 0.23 11.5 0.0 2.5 2 0 0 2 2 2 2 Tetratrico peptide repeat Apc3 PF12895.2 KEZ38696.1 - 0.00015 21.8 0.6 1.3 9.2 0.0 3.2 3 1 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KEZ38696.1 - 0.00026 20.4 0.1 0.024 14.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ38696.1 - 0.00047 20.0 2.5 0.29 11.0 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Arg_tRNA_synt_N PF03485.11 KEZ38696.1 - 0.00067 20.1 0.7 0.0015 19.0 0.1 1.9 2 0 0 2 2 1 1 Arginyl tRNA synthetase N terminal domain TPR_2 PF07719.12 KEZ38696.1 - 0.0022 17.7 11.9 0.012 15.5 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ38696.1 - 0.0029 17.2 0.2 0.1 12.4 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 KEZ38696.1 - 0.0038 17.3 4.6 0.059 13.4 0.1 3.1 1 1 1 3 3 3 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.9 KEZ38696.1 - 0.006 16.8 8.4 0.2 12.1 0.2 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEZ38696.1 - 0.015 15.1 0.5 5.2 7.0 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KEZ38696.1 - 0.053 13.9 0.3 31 5.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc5 PF12862.2 KEZ38696.1 - 0.11 12.3 2.7 3.4 7.5 0.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_9 PF13371.1 KEZ38696.1 - 0.14 12.0 3.3 34 4.3 0.1 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ38696.1 - 0.37 10.6 8.4 4.7 7.2 0.1 4.8 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ38696.1 - 0.89 9.5 5.7 75 3.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.16 KEZ38697.1 - 2.3e-20 73.1 0.4 2.2e-18 66.6 0.3 2.1 1 1 0 1 1 1 1 Acyl transferase domain Adap_comp_sub PF00928.16 KEZ38698.1 - 3.6e-58 196.7 0.0 2.2e-38 131.8 0.0 2.0 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEZ38698.1 - 0.0047 16.6 0.0 0.0072 16.0 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ECR1_N PF14382.1 KEZ38699.1 - 1.6e-11 43.2 0.1 3.2e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KEZ38699.1 - 6.4e-05 22.8 0.1 0.0005 19.9 0.1 2.3 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Aldedh PF00171.17 KEZ38700.1 - 5e-77 259.1 0.0 6e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RTA1 PF04479.8 KEZ38701.1 - 7.7e-19 68.0 8.4 1.1e-18 67.5 5.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Poxvirus_B22R_C PF13168.1 KEZ38701.1 - 0.24 10.6 0.5 0.39 9.9 0.3 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal PMP22_Claudin PF00822.15 KEZ38701.1 - 4.8 6.8 10.4 0.14 11.7 2.0 2.2 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin family DUF4055 PF13264.1 KEZ38702.1 - 0.053 13.5 0.0 0.053 13.5 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4055) NAD_binding_6 PF08030.7 KEZ38703.1 - 3.2e-17 62.8 0.0 4.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KEZ38703.1 - 4.6e-14 52.5 11.9 4.6e-14 52.5 8.3 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEZ38703.1 - 3e-10 39.9 0.0 6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Cytochrom_B_N PF00033.14 KEZ38703.1 - 1.1 8.6 13.5 0.22 10.8 1.9 3.0 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB YfhO PF09586.5 KEZ38703.1 - 6.5 4.6 10.7 9.2 4.1 7.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SNF2_N PF00176.18 KEZ38704.1 - 9.7e-82 274.1 0.2 1.8e-81 273.2 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KEZ38704.1 - 3.7e-45 152.4 2.6 1.2e-44 150.7 1.8 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KEZ38704.1 - 4.1e-32 110.9 8.0 4.1e-32 110.9 5.6 3.4 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 KEZ38704.1 - 1.7e-15 56.6 0.0 5.1e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KEZ38704.1 - 2.3e-08 33.2 0.4 1.8e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KEZ38704.1 - 2.5e-08 33.9 0.8 3.1e-07 30.3 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KEZ38704.1 - 7.4e-05 22.3 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KEZ38704.1 - 0.024 14.0 0.1 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 KEZ38704.1 - 0.028 14.3 0.2 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.26 KEZ38704.1 - 0.056 13.5 0.1 5.2 7.2 0.0 3.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain WD40 PF00400.27 KEZ38705.1 - 2.8e-28 96.7 5.2 2.6e-09 36.6 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 KEZ38705.1 - 0.0018 16.4 0.1 0.0025 16.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KEZ38705.1 - 0.029 13.1 0.1 0.19 10.4 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region Nucleoporin_N PF08801.6 KEZ38705.1 - 0.054 12.2 0.1 0.24 10.1 0.0 1.9 1 1 0 1 1 1 0 Nup133 N terminal like FTHFS PF01268.14 KEZ38706.1 - 8.9e-257 852.5 0.1 1.2e-256 852.1 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KEZ38706.1 - 4.5e-70 233.8 0.7 4.5e-70 233.8 0.5 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KEZ38706.1 - 1.1e-29 102.8 0.2 2.2e-29 101.8 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF3563 PF12086.3 KEZ38706.1 - 0.1 12.3 0.1 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Sedlin_N PF04628.8 KEZ38707.1 - 7.8e-20 71.0 0.0 9.7e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KEZ38707.1 - 0.018 14.7 0.0 0.06 13.0 0.0 1.7 1 1 0 1 1 1 0 Sybindin-like family MCM PF00493.18 KEZ38709.1 - 1.6e-141 470.8 0.0 2.6e-141 470.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KEZ38709.1 - 7.4e-35 120.2 31.9 7.4e-35 120.2 22.1 2.6 3 1 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KEZ38709.1 - 4.4e-20 72.3 0.3 2.7e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEZ38709.1 - 4.8e-08 32.4 0.0 2.5e-06 26.7 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEZ38709.1 - 3.3e-06 26.8 0.0 8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KEZ38709.1 - 0.0028 17.1 0.1 0.024 14.1 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KEZ38709.1 - 0.003 17.1 0.1 0.022 14.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KEZ38709.1 - 0.047 12.3 0.1 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain zf-TFIIB PF13453.1 KEZ38709.1 - 0.096 11.8 1.4 0.22 10.7 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.15 KEZ38710.1 - 4.3e-16 58.3 4.3 4.3e-16 58.3 3.0 3.0 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) AA_permease PF00324.16 KEZ38711.1 - 3.2e-102 342.3 27.2 3.7e-102 342.1 18.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ38711.1 - 6.1e-39 133.7 30.5 6.1e-39 133.7 21.2 1.4 1 1 1 2 2 2 1 Amino acid permease Spore_permease PF03845.8 KEZ38711.1 - 0.00036 19.2 3.5 0.0019 16.9 2.4 2.1 1 1 0 1 1 1 1 Spore germination protein DUF2207 PF09972.4 KEZ38711.1 - 0.25 9.9 6.7 0.54 8.7 0.1 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DDE_Tnp_IS240 PF13610.1 KEZ38712.1 - 0.047 13.6 2.5 0.095 12.6 1.8 1.5 1 0 0 1 1 1 0 DDE domain MscS_porin PF12795.2 KEZ38712.1 - 1.3 8.2 20.6 0.67 9.2 4.1 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain CENP-Q PF13094.1 KEZ38712.1 - 3.6 7.5 18.5 0.95 9.4 4.3 3.2 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit GFO_IDH_MocA PF01408.17 KEZ38713.1 - 2.6e-18 66.6 0.1 5.8e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KEZ38713.1 - 3.4e-06 26.8 0.0 6.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 KEZ38713.1 - 0.025 13.5 0.2 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase Fungal_trans_2 PF11951.3 KEZ38714.1 - 1.7e-12 46.6 0.0 2.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1092 PF06485.6 KEZ38714.1 - 0.031 13.2 0.0 0.076 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1092) Patatin PF01734.17 KEZ38715.1 - 1.2e-26 93.8 0.0 1.8e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C2H2_4 PF13894.1 KEZ38716.1 - 2.2e-07 30.7 14.4 0.13 12.6 0.5 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger Raptor_N PF14538.1 KEZ38716.1 - 0.018 14.8 0.1 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain zf-TRAF PF02176.13 KEZ38716.1 - 0.49 10.8 4.5 0.13 12.6 0.7 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2 PF00096.21 KEZ38716.1 - 0.52 10.7 22.1 0.31 11.4 0.5 4.8 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KEZ38716.1 - 1.7 8.8 4.1 20 5.4 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF981 PF06168.6 KEZ38718.1 - 0.065 13.0 0.2 0.065 13.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF981) FAD_binding_4 PF01565.18 KEZ38719.1 - 1.1e-29 102.6 1.4 2.1e-29 101.7 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ38719.1 - 0.041 13.8 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like GST_N_3 PF13417.1 KEZ38720.1 - 6.3e-16 58.3 0.1 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEZ38720.1 - 4.6e-13 48.9 0.0 8.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEZ38720.1 - 4.9e-09 36.2 0.0 8.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KEZ38720.1 - 0.0016 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 KEZ38720.1 - 0.0032 17.4 0.0 0.0061 16.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEZ38720.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain bZIP_1 PF00170.16 KEZ38721.1 - 0.0005 19.9 5.1 0.0005 19.9 3.5 1.9 2 0 0 2 2 2 1 bZIP transcription factor Filo_VP35 PF02097.10 KEZ38721.1 - 0.043 13.0 0.7 0.043 13.0 0.5 2.2 2 0 0 2 2 2 0 Filoviridae VP35 DUF3972 PF13118.1 KEZ38721.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Glyco_hydro_3 PF00933.16 KEZ38722.1 - 5.8e-80 268.4 0.0 8.2e-80 267.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ38722.1 - 9.3e-71 237.9 0.0 6.1e-70 235.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ38722.1 - 1.9e-24 85.3 0.8 4.3e-24 84.2 0.5 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KEZ38722.1 - 2e-18 66.4 0.0 3.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 KEZ38722.1 - 0.11 12.6 0.3 0.55 10.3 0.1 2.1 2 0 0 2 2 2 0 CARDB DUF3176 PF11374.3 KEZ38723.1 - 1.8e-32 111.4 3.3 3.6e-32 110.5 2.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Claudin_2 PF13903.1 KEZ38723.1 - 0.0037 16.9 0.9 0.011 15.3 0.0 2.1 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Peptidase_C2 PF00648.16 KEZ38724.1 - 7.9e-57 192.5 2.8 4.8e-37 127.5 0.3 2.7 3 0 0 3 3 3 2 Calpain family cysteine protease FTA4 PF13093.1 KEZ38725.1 - 5.5e-49 166.4 0.0 6.7e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FliT PF05400.8 KEZ38725.1 - 9.9 6.6 9.2 3.7 8.0 2.1 2.9 2 1 0 3 3 3 0 Flagellar protein FliT zf-CCHC PF00098.18 KEZ38726.1 - 5.1e-44 146.1 56.6 4.5e-08 32.6 1.1 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KEZ38726.1 - 4.3e-09 35.8 41.5 0.074 12.7 0.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 KEZ38726.1 - 5.2e-06 26.0 41.3 0.053 13.2 0.0 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 KEZ38726.1 - 0.053 13.0 0.4 0.053 13.0 0.3 7.1 4 2 3 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.1 KEZ38726.1 - 2.1 8.1 47.7 0.18 11.4 0.3 6.9 6 1 1 7 7 7 0 Zinc knuckle WD40 PF00400.27 KEZ38728.1 - 1.5e-54 180.0 7.6 2.3e-09 36.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEZ38728.1 - 0.0085 14.8 0.2 3 6.4 0.0 3.2 1 1 2 3 3 3 2 Nup133 N terminal like ISAV_HA PF06215.6 KEZ38728.1 - 0.11 10.7 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin TRAPP PF04051.11 KEZ38729.1 - 3.3e-36 124.0 0.0 3.9e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.3 KEZ38729.1 - 0.062 12.1 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.6 KEZ38730.1 - 0.025 14.3 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 LisH Nucleoplasmin PF03066.10 KEZ38731.1 - 0.28 10.6 2.4 0.42 10.1 1.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Chitin_synth_1 PF01644.12 KEZ38733.1 - 4.7e-81 270.3 0.3 7.2e-81 269.7 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KEZ38733.1 - 1.6e-31 107.7 0.0 3.3e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KEZ38733.1 - 1.1e-22 80.1 0.1 1.3e-16 60.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KEZ38733.1 - 2.3e-09 37.2 3.0 2.3e-09 37.2 2.1 2.3 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ38733.1 - 1.2e-07 31.8 0.0 4.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GHMP_kinases_N PF00288.21 KEZ38734.1 - 4.3e-11 42.7 0.0 1.1e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEZ38734.1 - 0.00025 21.1 0.0 0.00063 19.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DHDPS PF00701.17 KEZ38735.1 - 1.2e-27 96.2 0.0 1.6e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF676 PF05057.9 KEZ38736.1 - 1.6e-50 171.4 0.0 2.1e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEZ38736.1 - 4.8e-07 29.8 0.0 7.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ38736.1 - 2.7e-06 27.2 0.1 4.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ38736.1 - 0.0035 16.9 0.0 0.0082 15.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 KEZ38736.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Band_7 PF01145.20 KEZ38737.1 - 1.7e-25 89.9 4.8 1.9e-25 89.8 2.7 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 KEZ38737.1 - 0.011 15.1 1.0 0.018 14.4 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) UcrQ PF02939.11 KEZ38738.1 - 7.2e-29 99.4 0.3 8.9e-29 99.1 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.21 KEZ38739.1 - 2.9e-22 77.9 1.6 1.6e-21 75.5 0.2 2.6 2 2 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SAPS PF04499.10 KEZ38739.1 - 0.16 10.6 0.0 0.16 10.6 0.0 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Med3 PF11593.3 KEZ38739.1 - 0.4 9.8 6.2 0.11 11.7 0.6 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1761 PF08570.5 KEZ38740.1 - 2.8e-24 85.5 1.5 3.2e-24 85.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.13 KEZ38741.1 - 8.1e-53 178.3 0.0 1.3e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.12 KEZ38742.1 - 4.4e-42 144.0 0.1 1.8e-41 142.0 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family Acetyltransf_1 PF00583.19 KEZ38743.1 - 8.6e-14 51.3 0.9 1e-13 51.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEZ38743.1 - 6.8e-07 28.9 0.1 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEZ38743.1 - 0.0006 19.9 0.0 0.0022 18.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEZ38743.1 - 0.0011 19.0 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEZ38743.1 - 0.0072 16.1 0.2 0.027 14.3 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4093 PF13331.1 KEZ38743.1 - 0.046 13.9 0.2 0.087 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Mito_carr PF00153.22 KEZ38744.1 - 5.5e-71 234.3 0.4 2.2e-24 84.9 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein UPF0197 PF05251.7 KEZ38744.1 - 0.16 12.2 0.3 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0197) AhpC-TSA PF00578.16 KEZ38745.1 - 9.4e-26 89.9 0.0 1.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEZ38745.1 - 2.2e-17 62.9 0.1 2.8e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KEZ38745.1 - 0.01 15.7 0.0 0.081 12.8 0.0 2.1 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme adh_short PF00106.20 KEZ38747.1 - 7.5e-29 100.7 1.2 1.1e-28 100.3 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ38747.1 - 7.9e-22 78.2 0.8 8.6e-21 74.8 0.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ38747.1 - 4.3e-14 52.5 0.3 6e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ38747.1 - 3.1e-05 23.5 0.1 7.8e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Med16 PF11635.3 KEZ38747.1 - 0.11 10.3 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 UCR_14kD PF02271.11 KEZ38748.1 - 3e-36 123.3 0.4 3.6e-36 123.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.9 KEZ38749.1 - 2.9e-110 367.6 0.0 3.5e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 Recep_L_domain PF01030.19 KEZ38750.1 - 1.2e-05 25.2 0.3 0.041 13.8 0.0 3.8 2 2 1 3 3 3 2 Receptor L domain LRR_5 PF13306.1 KEZ38750.1 - 0.017 14.8 0.5 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) G-patch PF01585.18 KEZ38751.1 - 1.9e-13 49.9 0.8 1.2e-12 47.3 0.2 2.5 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 KEZ38751.1 - 3.2e-06 26.8 0.1 5.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ38751.1 - 2.3e-05 23.9 0.1 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ38751.1 - 0.006 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 KEZ38752.1 - 2e-85 286.6 0.0 2.5e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ38752.1 - 1.2e-16 61.4 0.0 3.1e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KEZ38752.1 - 0.00042 18.9 0.0 0.011 14.2 0.0 2.2 2 0 0 2 2 2 1 GH3 auxin-responsive promoter YCII PF03795.9 KEZ38753.1 - 2.7e-10 40.3 0.0 3.2e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Clathrin PF00637.15 KEZ38753.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Region in Clathrin and VPS DUF2408 PF10303.4 KEZ38754.1 - 5.8e-46 155.9 0.2 3.7e-26 91.8 0.0 4.6 4 1 0 4 4 4 4 Protein of unknown function (DUF2408) Sigma70_ner PF04546.8 KEZ38754.1 - 0.022 14.3 6.8 0.071 12.7 4.7 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 KEZ38754.1 - 0.27 11.6 9.1 0.57 10.6 6.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein BSP_II PF05432.6 KEZ38754.1 - 0.98 8.6 9.8 1.6 7.9 6.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) AF1Q PF15017.1 KEZ38754.1 - 1.2 9.0 6.6 8.9 6.3 2.5 2.3 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Spc24 PF08286.6 KEZ38754.1 - 5.8 6.6 8.4 12 5.6 0.0 3.6 4 1 1 5 5 5 0 Spc24 subunit of Ndc80 Ribosomal_60s PF00428.14 KEZ38755.1 - 1.3e-26 92.8 12.0 1.5e-26 92.5 8.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 KEZ38755.1 - 0.22 11.3 6.1 0.34 10.7 4.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF3824 PF12868.2 KEZ38755.1 - 2 9.3 4.9 3 8.7 3.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) UBA PF00627.26 KEZ38756.1 - 0.0015 18.2 0.1 0.0042 16.9 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 KEZ38756.1 - 0.037 14.1 0.2 0.089 12.9 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) UBX PF00789.15 KEZ38756.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 UBX domain PLRV_ORF5 PF01690.12 KEZ38756.1 - 0.13 11.3 14.4 0.19 10.8 10.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Motile_Sperm PF00635.21 KEZ38757.1 - 5.6e-24 83.8 0.1 1.1e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FA_desaturase PF00487.19 KEZ38758.1 - 2.2e-29 102.7 17.8 2.8e-29 102.3 12.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KEZ38758.1 - 7.2e-20 69.9 0.3 1.3e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) TIG PF01833.19 KEZ38759.1 - 0.17 11.8 1.8 0.19 11.7 0.4 1.7 2 0 0 2 2 2 0 IPT/TIG domain ICE2 PF08426.5 KEZ38760.1 - 7.3e-135 449.7 12.6 8.5e-135 449.5 8.8 1.0 1 0 0 1 1 1 1 ICE2 Abhydrolase_5 PF12695.2 KEZ38761.1 - 5.8e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ38761.1 - 1.8e-05 24.7 0.2 3e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Mur_ligase_M PF08245.7 KEZ38762.1 - 3.3e-10 40.3 0.0 8.3e-10 39.0 0.0 1.8 2 1 0 2 2 2 1 Mur ligase middle domain DUF218 PF02698.12 KEZ38762.1 - 1.2e-07 31.3 0.0 3.8e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 DUF218 domain Mur_ligase_C PF02875.16 KEZ38762.1 - 0.01 15.8 0.0 0.076 13.0 0.0 2.4 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain UPF0146 PF03686.8 KEZ38762.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Pkinase PF00069.20 KEZ38764.1 - 2.6e-70 236.5 0.0 4.8e-70 235.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ38764.1 - 7.7e-51 172.6 0.0 1.2e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ38764.1 - 0.001 18.1 0.0 0.0027 16.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEZ38764.1 - 0.04 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RTTN_N PF14726.1 KEZ38764.1 - 0.5 10.9 3.2 2.2 8.9 0.3 2.6 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning MFS_1 PF07690.11 KEZ38765.1 - 1.5e-33 115.9 35.2 1.5e-33 115.9 24.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ38765.1 - 0.00019 20.1 27.1 0.0023 16.5 4.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KEZ38765.1 - 0.69 9.7 10.3 0.088 12.6 0.8 3.6 4 0 0 4 4 4 0 MFS_1 like family CASP_C PF08172.7 KEZ38766.1 - 0.023 13.7 0.9 0.04 12.9 0.7 1.3 1 0 0 1 1 1 0 CASP C terminal zf-C2H2 PF00096.21 KEZ38766.1 - 0.062 13.6 1.5 0.089 13.1 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type NEMO PF11577.3 KEZ38766.1 - 0.063 13.0 1.5 0.13 11.9 1.1 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO NYD-SP28_assoc PF14775.1 KEZ38766.1 - 0.5 10.0 2.9 1.1 9.0 2.0 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain UPF1_Zn_bind PF09416.5 KEZ38767.1 - 4.5e-72 240.6 3.9 2.1e-71 238.4 1.0 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KEZ38767.1 - 2e-60 203.6 0.0 3.7e-60 202.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ38767.1 - 9.2e-57 192.3 1.9 1.4e-56 191.7 1.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ38767.1 - 1.5e-14 53.4 1.5 1.8e-14 53.2 0.2 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 KEZ38767.1 - 1.8e-13 50.5 0.4 1.6e-10 40.8 0.0 2.4 1 1 0 2 2 2 2 AAA domain ResIII PF04851.10 KEZ38767.1 - 4.8e-08 33.0 0.0 9.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 KEZ38767.1 - 1.5e-05 24.7 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 KEZ38767.1 - 8.2e-05 21.7 0.3 0.00084 18.4 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KEZ38767.1 - 0.00011 21.7 0.1 0.33 10.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 KEZ38767.1 - 0.00023 20.2 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 KEZ38767.1 - 0.00033 20.2 0.2 0.00084 18.8 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KEZ38767.1 - 0.00051 19.4 0.0 0.012 14.8 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 KEZ38767.1 - 0.024 13.8 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 KEZ38767.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KEZ38767.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEZ38767.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 KEZ38767.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.24 KEZ38767.1 - 0.26 11.4 0.5 0.69 10.1 0.4 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Brix PF04427.13 KEZ38768.1 - 1e-45 155.7 0.3 1.3e-45 155.4 0.2 1.1 1 0 0 1 1 1 1 Brix domain TPR_11 PF13414.1 KEZ38769.1 - 1.4e-51 171.9 21.6 1.6e-12 46.8 0.7 6.6 4 2 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 KEZ38769.1 - 8.3e-38 126.4 19.8 0.00011 21.6 0.0 11.4 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ38769.1 - 3.3e-36 120.2 17.6 0.0002 21.0 0.0 11.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ38769.1 - 9.3e-27 93.0 6.3 1.4e-06 28.7 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ38769.1 - 9.4e-21 73.5 20.8 8.3e-07 28.8 0.0 7.6 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ38769.1 - 1.7e-16 58.9 5.4 0.051 13.7 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ38769.1 - 2e-14 53.6 17.4 1.3e-05 25.4 1.0 6.0 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ38769.1 - 1.2e-13 49.7 15.2 0.1 12.4 0.0 10.1 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ38769.1 - 1.6e-11 43.7 20.4 0.067 13.8 1.0 9.4 7 3 4 11 11 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ38769.1 - 5.4e-10 38.9 8.9 0.65 9.8 0.0 6.4 4 1 3 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ38769.1 - 4.5e-09 35.4 18.2 0.12 12.2 0.2 9.6 8 2 2 10 10 10 1 Tetratricopeptide repeat Apc3 PF12895.2 KEZ38769.1 - 5.8e-08 32.7 17.3 0.011 15.8 0.8 5.8 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEZ38769.1 - 1.4e-05 25.2 24.9 0.37 11.3 0.0 9.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ38769.1 - 0.00056 19.9 14.6 1.1 9.3 0.1 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ38769.1 - 0.0022 18.2 1.0 0.97 10.0 0.2 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KEZ38769.1 - 0.0084 15.3 1.6 37 3.6 0.0 4.6 4 0 0 4 4 4 0 SHNi-TPR Ribosomal_L22 PF00237.14 KEZ38769.1 - 0.028 14.3 0.1 0.069 13.0 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e TPR_10 PF13374.1 KEZ38769.1 - 0.033 14.1 8.2 2.5 8.1 0.8 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 KEZ38769.1 - 3.4 8.4 9.5 3.5 8.3 0.1 4.6 4 0 0 4 4 4 0 Sel1 repeat Glyco_hydro_47 PF01532.15 KEZ38770.1 - 3.3e-166 553.4 0.0 4.2e-166 553.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Aminotran_4 PF01063.14 KEZ38770.1 - 3.6e-16 59.3 0.0 8.1e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 KEZ38771.1 - 4.1e-05 22.8 0.0 8.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Myosin_tail_1 PF01576.14 KEZ38771.1 - 0.00016 19.5 54.6 0.0028 15.4 28.7 2.6 1 1 1 2 2 2 2 Myosin tail Filament PF00038.16 KEZ38771.1 - 0.0011 18.5 46.2 0.0048 16.4 16.6 4.0 1 1 1 2 2 2 1 Intermediate filament protein TSC22 PF01166.13 KEZ38771.1 - 0.0091 15.9 0.5 0.0091 15.9 0.4 5.4 6 0 0 6 6 6 2 TSC-22/dip/bun family IncA PF04156.9 KEZ38771.1 - 0.078 12.5 52.2 0.049 13.2 10.3 3.7 1 1 2 3 3 3 0 IncA protein NPV_P10 PF05531.7 KEZ38771.1 - 0.079 13.2 9.4 1 9.6 0.2 3.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.3 KEZ38771.1 - 0.19 11.5 50.0 0.46 10.3 4.7 5.5 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding Baculo_PEP_C PF04513.7 KEZ38771.1 - 0.4 10.5 10.7 1.9 8.3 1.6 2.8 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_LMP2 PF07415.6 KEZ38771.1 - 0.74 8.3 1.1 1.1 7.8 0.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Reo_sigmaC PF04582.7 KEZ38771.1 - 1.4 8.0 15.0 0.62 9.1 3.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 KEZ38771.1 - 3.1 7.6 52.6 2.1 8.1 2.4 6.8 3 1 2 6 6 6 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 KEZ38771.1 - 8.1 6.2 50.4 2.3 8.0 16.5 4.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DnaJ PF00226.26 KEZ38772.1 - 7.4e-23 80.0 0.3 1.1e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4510 PF14971.1 KEZ38772.1 - 2.4 8.3 5.0 4.7 7.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) Porin_3 PF01459.17 KEZ38773.1 - 2e-58 197.8 7.7 2.3e-58 197.6 5.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.16 KEZ38774.1 - 4.8e-69 232.6 0.0 6.4e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KEZ38774.1 - 4.5e-36 123.3 0.0 7.4e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KEZ38774.1 - 1.1e-28 99.8 0.0 2.3e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KEZ38774.1 - 7e-09 35.2 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KEZ38774.1 - 0.00047 18.9 0.0 0.085 11.5 0.0 2.8 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KEZ38774.1 - 0.0019 17.1 0.1 0.0062 15.4 0.0 1.8 1 1 0 1 1 1 1 NAD synthase UQ_con PF00179.21 KEZ38775.1 - 6.5e-49 164.9 0.0 7.3e-49 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ38775.1 - 0.00038 20.2 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEZ38775.1 - 0.14 12.1 0.9 0.19 11.6 0.6 1.7 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 KEZ38776.1 - 5.3e-69 232.6 10.9 5.3e-69 232.6 7.6 1.7 2 0 0 2 2 2 1 Pex19 protein family DUF445 PF04286.7 KEZ38776.1 - 0.019 14.4 2.4 0.15 11.5 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) BamHI PF02923.10 KEZ38776.1 - 0.13 12.2 0.0 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease BamHI ABC1 PF03109.11 KEZ38778.1 - 1.1e-33 115.6 0.0 1.8e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Rad52_Rad22 PF04098.10 KEZ38779.1 - 2.6e-59 199.3 0.0 3.5e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Gln-synt_C PF00120.19 KEZ38780.1 - 2.8e-51 174.1 0.0 4.3e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 KEZ38780.1 - 8.8e-23 81.2 0.1 1.5e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_76 PF03663.9 KEZ38781.1 - 4.7e-147 490.2 8.2 5.8e-147 489.9 5.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEZ38781.1 - 0.019 14.0 6.4 0.4 9.6 0.1 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 ERG4_ERG24 PF01222.12 KEZ38783.1 - 6.2e-140 466.5 19.6 7.2e-140 466.3 13.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Translin PF01997.11 KEZ38784.1 - 2e-43 148.3 0.1 2.6e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 Translin family ATP-synt_C PF00137.16 KEZ38785.1 - 1.4e-31 108.1 30.5 2.5e-19 68.9 8.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 KEZ38785.1 - 1.9 8.0 6.2 0.29 10.6 1.3 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Ribosomal_L7Ae PF01248.21 KEZ38786.1 - 2.7e-25 87.6 0.1 3.2e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KEZ38786.1 - 0.0001 22.1 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KEZ38786.1 - 0.021 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Syja_N PF02383.13 KEZ38787.1 - 5.6e-88 294.7 0.0 8.7e-88 294.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KEZ38787.1 - 1.4e-31 108.2 0.0 2.7e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Transketolase_N PF00456.16 KEZ38788.1 - 1.6e-155 516.9 0.1 2.2e-155 516.5 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KEZ38788.1 - 5.2e-44 149.8 0.0 9.7e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEZ38788.1 - 3.9e-14 52.6 0.0 1.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Btz PF09405.5 KEZ38789.1 - 4.6e-28 97.8 5.2 1.1e-27 96.6 3.6 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding ZZ PF00569.12 KEZ38790.1 - 1.7e-17 62.6 59.3 3.5e-05 23.2 4.8 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Baculo_IE-1 PF05290.6 KEZ38790.1 - 0.0041 16.8 0.6 0.0041 16.8 0.4 2.4 3 0 0 3 3 3 1 Baculovirus immediate-early protein (IE-0) COPIIcoated_ERV PF07970.7 KEZ38791.1 - 1.8e-33 116.0 0.1 2.4e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KEZ38791.1 - 2.4e-22 78.7 0.0 4.1e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DnaJ_CXXCXGXG PF00684.14 KEZ38792.1 - 0.024 14.7 7.5 0.028 14.4 0.4 2.5 1 1 1 2 2 2 0 DnaJ central domain TMEM95 PF15203.1 KEZ38792.1 - 0.82 9.0 4.1 1 8.7 2.8 1.2 1 0 0 1 1 1 0 TMEM95 family HEAT PF02985.17 KEZ38793.1 - 5.6e-12 44.6 0.3 0.036 14.1 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 KEZ38793.1 - 0.00017 21.7 0.0 0.15 12.3 0.0 3.4 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 KEZ38793.1 - 0.00068 20.0 0.1 0.56 10.7 0.0 3.8 3 2 1 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.15 KEZ38793.1 - 0.055 11.7 0.1 0.77 8.0 0.1 2.1 2 1 1 3 3 3 0 Adaptin N terminal region Cnd1 PF12717.2 KEZ38793.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 KEZ38793.1 - 0.095 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CLASP_N PF12348.3 KEZ38793.1 - 0.14 11.4 0.3 1.1 8.5 0.1 2.0 1 1 1 2 2 2 0 CLASP N terminal Aconitase PF00330.15 KEZ38794.1 - 1.7e-153 511.4 0.0 4.8e-153 509.9 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEZ38794.1 - 3.7e-38 130.5 0.0 6e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 KEZ38794.1 - 0.042 12.4 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) WD40 PF00400.27 KEZ38795.1 - 8e-50 165.0 17.8 2.5e-11 42.9 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KEZ38795.1 - 4.2e-08 31.8 2.9 0.011 13.9 0.0 4.5 2 1 1 5 5 5 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KEZ38795.1 - 0.00084 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 KEZ38795.1 - 0.0017 18.0 0.2 0.047 13.3 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RicinB_lectin_2 PF14200.1 KEZ38795.1 - 0.039 14.3 0.8 0.15 12.4 0.0 2.4 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Nbas_N PF15492.1 KEZ38795.1 - 0.041 12.9 0.0 5.5 6.0 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 KEZ38795.1 - 0.052 11.7 0.0 0.2 9.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) HPS3_N PF14761.1 KEZ38795.1 - 0.077 12.3 0.0 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.6 KEZ38795.1 - 0.087 11.5 2.4 0.19 10.4 0.3 2.6 2 1 1 3 3 3 0 Nup133 N terminal like MRJP PF03022.11 KEZ38795.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Major royal jelly protein Hira PF07569.6 KEZ38795.1 - 0.15 11.2 0.4 7.6 5.6 0.0 2.7 1 1 2 3 3 3 0 TUP1-like enhancer of split FHA PF00498.21 KEZ38796.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain TAT_signal PF10518.4 KEZ38797.1 - 1.8 8.7 7.5 7.7 6.7 5.2 2.2 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Actin PF00022.14 KEZ38798.1 - 2.1e-132 441.2 0.0 2.4e-132 441.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEZ38798.1 - 0.18 10.3 0.0 11 4.5 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein PIG-F PF06699.6 KEZ38800.1 - 2.7e-53 180.7 8.7 3e-53 180.6 5.4 1.4 1 1 1 2 2 2 1 GPI biosynthesis protein family Pig-F Romo1 PF10247.4 KEZ38800.1 - 0.4 10.8 2.2 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Bacteriocin_IIc PF10439.4 KEZ38800.1 - 0.74 9.9 6.2 3.2 7.9 1.6 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide VIT1 PF01988.14 KEZ38800.1 - 2.1 7.8 5.3 0.39 10.1 0.9 1.7 2 0 0 2 2 2 0 VIT family MMR_HSR1_C PF08438.5 KEZ38801.1 - 4.7e-31 107.2 0.0 1.1e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KEZ38801.1 - 1.2e-18 67.0 0.0 3.4e-18 65.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ38801.1 - 5.7e-09 35.4 0.3 2.9e-07 29.8 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEZ38801.1 - 0.0021 17.4 0.1 2.2 7.6 0.0 3.0 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KEZ38801.1 - 0.0033 16.2 0.0 0.0077 15.0 0.0 1.6 1 0 0 1 1 1 1 ArgK protein Dynamin_N PF00350.18 KEZ38801.1 - 0.014 15.2 0.1 0.17 11.7 0.2 2.3 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.1 KEZ38801.1 - 0.11 12.1 0.2 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KEZ38801.1 - 0.13 12.5 0.0 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter SET PF00856.23 KEZ38802.1 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 SET domain Fungal_trans PF04082.13 KEZ38804.1 - 5.3e-31 107.4 0.1 8.4e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Macoilin PF09726.4 KEZ38804.1 - 5.5 5.1 7.5 2.6 6.2 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein GDPD PF03009.12 KEZ38805.1 - 2.2e-34 119.1 0.0 3.3e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KEZ38805.1 - 0.00034 20.7 2.1 0.00057 20.0 0.4 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF591 PF04569.9 KEZ38805.1 - 0.21 11.6 5.9 0.4 10.7 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function Plus-3 PF03126.13 KEZ38806.1 - 1.4e-20 73.2 0.0 3e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.8 KEZ38807.1 - 5.3e-65 218.0 0.0 6.9e-65 217.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 KEZ38807.1 - 0.00029 21.1 0.0 0.00048 20.4 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin PLDc PF00614.17 KEZ38808.1 - 7.4e-16 57.3 0.7 6.8e-07 28.8 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KEZ38808.1 - 3.4e-11 42.9 0.1 2.1e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KEZ38808.1 - 6.6e-09 35.5 0.0 4.4e-08 32.8 0.0 2.5 2 1 0 2 2 2 1 PX domain Tubulin PF00091.20 KEZ38809.1 - 6.6e-73 245.0 0.0 9.6e-73 244.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEZ38809.1 - 2.4e-45 153.6 0.4 3.6e-45 153.0 0.0 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEZ38809.1 - 7.2e-08 32.4 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF1814 PF08843.6 KEZ38810.1 - 7.5e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) AAA_17 PF13207.1 KEZ38812.1 - 2.2e-08 34.9 1.5 1.2e-07 32.5 0.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEZ38812.1 - 2.3e-06 27.9 1.2 3.3e-05 24.2 0.8 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KEZ38812.1 - 5.1e-06 26.1 0.0 6.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 KEZ38812.1 - 3.5e-05 22.8 0.2 0.00012 21.0 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 KEZ38812.1 - 0.00047 19.3 0.5 0.003 16.6 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KEZ38812.1 - 0.00081 19.4 0.1 0.0018 18.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KEZ38812.1 - 0.0035 17.2 0.8 0.1 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KEZ38812.1 - 0.0044 16.4 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA_19 PF13245.1 KEZ38812.1 - 0.0044 16.7 0.2 0.011 15.4 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA PF00004.24 KEZ38812.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KEZ38812.1 - 0.017 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 KEZ38812.1 - 0.019 14.6 0.5 0.032 13.9 0.4 1.3 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.7 KEZ38812.1 - 0.023 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEZ38812.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEZ38812.1 - 0.041 12.7 0.1 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.15 KEZ38812.1 - 0.044 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 KEZ38812.1 - 0.051 12.5 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 KEZ38812.1 - 0.073 12.5 0.5 0.15 11.4 0.3 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KEZ38812.1 - 0.088 12.5 0.3 0.56 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KEZ38812.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KEZ38812.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KEZ38812.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SKI PF01202.17 KEZ38812.1 - 0.14 12.0 0.2 8.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase C2 PF00168.25 KEZ38813.1 - 1.2e-13 50.7 0.0 2.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain UPF0546 PF10639.4 KEZ38814.1 - 3.4e-34 117.0 0.1 7.8e-34 115.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 KEZ38814.1 - 0.00099 19.1 3.4 0.0079 16.2 1.9 2.1 2 0 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 KEZ38814.1 - 0.066 12.8 1.4 0.12 12.0 1.0 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF2011 PF09428.5 KEZ38815.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.9 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Proteasome PF00227.21 KEZ38816.1 - 2.2e-47 160.8 0.0 3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEZ38816.1 - 6.3e-12 44.5 0.1 6.3e-12 44.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 KEZ38816.1 - 0.34 10.4 3.6 0.16 11.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) HEAT_EZ PF13513.1 KEZ38817.1 - 4.1e-17 62.1 15.5 3.4e-06 27.3 0.6 9.9 9 1 2 11 11 10 3 HEAT-like repeat HEAT PF02985.17 KEZ38817.1 - 8.5e-16 56.5 4.5 0.012 15.5 0.0 7.4 7 0 0 7 7 6 3 HEAT repeat HEAT_2 PF13646.1 KEZ38817.1 - 2.3e-15 56.6 19.8 1.9e-05 24.8 0.8 7.7 4 2 4 8 8 8 3 HEAT repeats Adaptin_N PF01602.15 KEZ38817.1 - 5.3e-14 51.4 1.0 4.5e-05 21.9 0.0 3.6 3 0 0 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KEZ38817.1 - 3.8e-09 36.8 0.2 0.0035 17.6 0.0 6.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KEZ38817.1 - 5.7e-07 29.5 1.6 0.079 12.8 0.0 4.5 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 KEZ38817.1 - 2.3e-06 27.1 0.1 0.0059 15.9 0.0 4.2 4 1 1 5 5 5 1 CLASP N terminal UME PF08064.8 KEZ38817.1 - 9e-06 25.5 0.1 0.59 10.1 0.0 5.7 4 2 3 7 7 7 1 UME (NUC010) domain IBN_N PF03810.14 KEZ38817.1 - 3.7e-05 23.5 5.4 0.00011 22.0 0.1 3.6 4 0 0 4 4 3 1 Importin-beta N-terminal domain Arm PF00514.18 KEZ38817.1 - 4.3e-05 23.1 5.4 0.062 13.1 0.1 6.3 7 0 0 7 7 5 1 Armadillo/beta-catenin-like repeat ParcG PF10274.4 KEZ38817.1 - 5e-05 23.2 0.1 0.42 10.5 0.0 3.7 3 1 0 3 3 3 2 Parkin co-regulated protein RecO_C PF02565.10 KEZ38817.1 - 0.0001 22.1 0.5 0.0041 16.9 0.1 3.1 3 0 0 3 3 3 1 Recombination protein O C terminal DUF2454 PF10521.4 KEZ38817.1 - 0.00075 18.5 0.0 0.013 14.5 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) V-ATPase_H_N PF03224.9 KEZ38817.1 - 0.044 12.8 1.0 6.7 5.7 0.1 3.8 3 1 0 4 4 4 0 V-ATPase subunit H Dopey_N PF04118.9 KEZ38817.1 - 0.053 12.2 1.6 9.2 4.9 0.1 3.8 4 0 0 4 4 4 0 Dopey, N-terminal Pico_P2B PF01552.12 KEZ38817.1 - 0.093 12.8 0.2 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 Picornavirus 2B protein HEAT_PBS PF03130.11 KEZ38817.1 - 0.14 12.7 8.2 0.41 11.2 0.2 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat CorA PF01544.13 KEZ38818.1 - 0.033 13.2 5.5 0.092 11.7 3.8 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Claudin_2 PF13903.1 KEZ38818.1 - 0.097 12.3 0.9 0.17 11.5 0.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 KEZ38819.1 - 5.7e-08 32.9 1.1 1e-07 32.1 0.8 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.15 KEZ38819.1 - 0.037 13.6 3.8 0.1 12.2 2.7 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Spermine_synth PF01564.12 KEZ38820.1 - 5.7e-96 320.1 0.0 7.4e-96 319.8 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KEZ38820.1 - 0.00057 19.8 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ38820.1 - 0.00061 19.3 0.0 0.00097 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ38820.1 - 0.0008 19.9 0.0 0.0014 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KEZ38820.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_23 PF13489.1 KEZ38820.1 - 0.014 15.1 0.0 0.098 12.3 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KEZ38820.1 - 0.072 12.2 0.3 1.1 8.4 0.1 2.3 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_12 PF08242.7 KEZ38820.1 - 0.11 13.0 0.2 0.47 10.9 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_30 PF05430.6 KEZ38820.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase G-alpha PF00503.15 KEZ38821.1 - 8.4e-120 400.0 0.8 1e-119 399.7 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KEZ38821.1 - 4e-14 52.2 0.5 9.6e-09 34.7 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ38821.1 - 0.00026 20.2 0.2 0.062 12.4 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 KEZ38821.1 - 0.041 13.2 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ38821.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEZ38821.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pro_CA PF00484.14 KEZ38822.1 - 1.8e-45 154.6 0.1 2.1e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ODC_AZ PF02100.12 KEZ38822.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme Methyltransf_23 PF13489.1 KEZ38823.1 - 3.8e-12 46.2 0.0 5.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ38823.1 - 3e-05 24.4 0.0 0.0029 18.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ38823.1 - 0.00033 20.2 0.0 0.036 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ38823.1 - 0.00095 19.6 0.0 0.22 12.0 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ38823.1 - 0.0018 17.4 0.0 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KEZ38823.1 - 0.085 13.4 0.0 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ38823.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TFIIF_alpha PF05793.7 KEZ38824.1 - 0.14 10.4 9.0 0.26 9.5 6.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF605 PF04652.11 KEZ38824.1 - 1.3 8.3 20.3 2.7 7.3 14.0 1.5 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 KEZ38824.1 - 9.7 4.7 16.0 15 4.0 11.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Not1 PF04054.10 KEZ38825.1 - 2.8e-100 335.8 0.0 5e-100 335.0 0.0 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KEZ38825.1 - 5.9e-49 165.5 1.8 1.5e-48 164.1 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Seipin PF06775.9 KEZ38826.1 - 1.5e-41 142.1 0.2 2.5e-41 141.3 0.1 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.18 KEZ38826.1 - 3.6e-19 68.7 0.0 9.7e-19 67.3 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KEZ38826.1 - 1.8e-10 40.0 0.1 3.7e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KEZ38826.1 - 4e-06 26.2 0.0 1.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KEZ38826.1 - 3.3e-05 23.3 0.1 7.3e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain NTF2 PF02136.15 KEZ38828.1 - 9.1e-30 103.4 0.4 1e-29 103.3 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain OKR_DC_1_C PF03711.10 KEZ38828.1 - 0.0014 18.6 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Imm35 PF15581.1 KEZ38828.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 Immunity protein 35 Ribosomal_L7Ae PF01248.21 KEZ38829.1 - 5.7e-21 73.8 0.5 5.7e-21 73.8 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KEZ38829.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 MOZ_SAS PF01853.13 KEZ38830.1 - 3.9e-80 267.5 0.1 5.5e-80 267.0 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KEZ38830.1 - 0.00018 21.1 7.1 0.00018 21.1 4.9 2.2 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.1 KEZ38830.1 - 0.03 14.3 2.8 0.22 11.5 2.1 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.17 KEZ38830.1 - 0.052 13.2 1.0 0.15 11.7 0.7 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KEZ38830.1 - 0.18 11.1 2.4 0.51 9.6 1.7 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 KEZ38830.1 - 0.94 9.3 11.9 0.064 13.0 3.9 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 KEZ38830.1 - 9.7 6.0 11.2 1.4 8.6 4.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain ENTH PF01417.15 KEZ38831.1 - 1.1e-49 167.4 0.1 1.8e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KEZ38831.1 - 0.00056 18.6 0.0 0.0011 17.7 0.0 1.5 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 KEZ38831.1 - 0.014 14.9 0.8 0.014 14.9 0.5 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif VHS PF00790.14 KEZ38831.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 VHS domain IL6 PF00489.12 KEZ38833.1 - 0.00047 19.7 0.1 0.00078 19.0 0.0 1.2 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family AKNA PF12443.3 KEZ38833.1 - 0.0048 16.8 2.6 0.0048 16.8 1.8 1.9 2 0 0 2 2 2 1 AT-hook-containing transcription factor DUF4537 PF15057.1 KEZ38833.1 - 0.0049 16.6 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF4463 PF14703.1 KEZ38833.1 - 0.34 11.4 1.7 0.57 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Nup96 PF12110.3 KEZ38834.1 - 6.9e-92 307.6 0.9 1e-91 307.0 0.7 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KEZ38834.1 - 1e-46 158.2 0.0 1.6e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase ParA PF10609.4 KEZ38834.1 - 3.9e-31 106.7 0.2 1.8e-30 104.6 0.1 2.2 2 0 0 2 2 2 1 ParA/MinD ATPase like Nucleoporin_FG PF13634.1 KEZ38834.1 - 3.6e-05 23.9 354.8 0.21 11.8 51.6 10.1 3 2 3 6 6 6 1 Nucleoporin FG repeat region CbiA PF01656.18 KEZ38834.1 - 0.02 14.3 5.2 0.9 8.9 0.0 2.4 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 KEZ38834.1 - 0.047 12.8 0.0 0.5 9.5 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family UCH_1 PF13423.1 KEZ38835.1 - 1.7e-42 145.8 0.6 6e-22 78.4 0.7 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KEZ38835.1 - 1.9e-27 96.5 0.0 3.1e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KEZ38835.1 - 0.0023 17.0 0.2 0.0064 15.6 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_2 PF13240.1 KEZ38835.1 - 0.26 10.8 1.9 0.33 10.4 0.4 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Mito_carr PF00153.22 KEZ38837.1 - 1.1e-54 182.0 3.2 9e-20 70.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COX7C PF02935.11 KEZ38837.1 - 0.026 14.2 0.1 0.073 12.8 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Glyco_hydro_43 PF04616.9 KEZ38838.1 - 2.7e-66 223.5 0.2 3.5e-66 223.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 VWA_2 PF13519.1 KEZ38839.1 - 1.1e-09 38.5 2.6 6.7e-06 26.3 0.0 2.8 2 1 1 3 3 3 2 von Willebrand factor type A domain VWA PF00092.23 KEZ38839.1 - 0.0011 18.7 1.2 0.9 9.2 0.0 2.5 1 1 1 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 KEZ38839.1 - 0.05 12.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Methyltransf_25 PF13649.1 KEZ38841.1 - 3.4e-09 36.9 0.0 6.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ38841.1 - 2e-08 33.9 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ38841.1 - 3.4e-06 27.4 0.0 7.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ38841.1 - 1.6e-05 25.3 0.0 2.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ38841.1 - 5.6e-05 23.6 0.0 8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ38841.1 - 6.1e-05 22.7 0.0 8.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ38841.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 KEZ38841.1 - 0.007 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme PHY PF00360.15 KEZ38842.1 - 6.8e-27 93.7 0.0 2.6e-26 91.8 0.0 1.9 2 0 0 2 2 2 1 Phytochrome region HATPase_c PF02518.21 KEZ38842.1 - 1.3e-18 66.7 0.2 2.8e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEZ38842.1 - 1.5e-17 63.5 0.0 2.8e-16 59.5 0.0 2.8 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KEZ38842.1 - 5.5e-13 48.7 0.3 1.9e-12 47.0 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KEZ38842.1 - 1e-11 45.2 0.0 1.3e-10 41.6 0.0 2.7 3 0 0 3 3 3 1 GAF domain PAS_2 PF08446.6 KEZ38842.1 - 1.9e-08 34.7 0.0 5.7e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 KEZ38842.1 - 0.0029 17.2 0.4 0.0079 15.8 0.2 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ApbA PF02558.11 KEZ38843.1 - 8.1e-33 112.9 0.0 1.1e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KEZ38843.1 - 8.7e-26 90.3 0.0 1.4e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 KEZ38843.1 - 0.031 14.6 0.1 0.089 13.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 KEZ38844.1 - 1.3e-10 41.0 9.8 2e-10 40.3 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ38844.1 - 0.013 14.3 0.0 0.096 11.5 0.0 2.1 1 1 0 1 1 1 0 Fungal specific transcription factor domain TRAUB PF08164.7 KEZ38845.1 - 4.4e-28 97.2 0.2 3.5e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KEZ38845.1 - 4.9e-28 97.8 0.3 4.9e-28 97.8 0.2 2.5 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Chal_sti_synt_N PF00195.14 KEZ38846.1 - 3.5e-23 82.0 0.1 5.8e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 KEZ38846.1 - 1.6e-20 73.5 0.0 3.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 KEZ38846.1 - 1.8e-06 27.2 0.0 2.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 KEZ38846.1 - 0.00054 19.9 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KEZ38846.1 - 0.014 14.9 0.1 0.047 13.3 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CAS_CSE1 PF03378.10 KEZ38846.1 - 0.23 9.7 0.0 0.4 8.9 0.0 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus adh_short PF00106.20 KEZ38847.1 - 4.2e-20 72.3 0.0 7.1e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ38847.1 - 4e-11 42.9 0.0 9.7e-11 41.6 0.0 1.6 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEZ38847.1 - 3.5e-07 30.2 0.0 1e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ38847.1 - 0.0091 16.0 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEZ38847.1 - 0.012 14.5 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEZ38847.1 - 0.051 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase BUD22 PF09073.5 KEZ38848.1 - 1.2e-60 205.8 42.7 4.5e-60 203.9 29.6 1.7 1 1 0 1 1 1 1 BUD22 HGTP_anticodon2 PF12745.2 KEZ38848.1 - 9.5 5.2 12.7 48 2.9 0.0 2.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Mito_carr PF00153.22 KEZ38849.1 - 3.2e-68 225.4 2.8 7.5e-25 86.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KEZ38849.1 - 0.077 13.0 0.1 0.077 13.0 0.1 2.9 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family RCC1 PF00415.13 KEZ38851.1 - 7.8e-21 74.0 4.8 2e-06 27.8 0.1 6.7 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KEZ38851.1 - 1e-16 60.9 0.0 4.9e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KEZ38851.1 - 2.2e-08 34.3 0.6 1.3e-07 31.9 0.3 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KEZ38851.1 - 4e-08 32.6 1.7 4e-08 32.6 1.2 5.0 7 0 0 7 7 7 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KEZ38851.1 - 1.4e-05 24.8 0.5 0.14 12.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KEZ38851.1 - 0.00047 20.4 0.1 0.0013 19.0 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ38851.1 - 0.022 14.5 0.2 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat DUF639 PF04842.7 KEZ38851.1 - 0.047 11.8 0.0 0.07 11.2 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF1389 PF07146.6 KEZ38851.1 - 0.18 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) ATG13 PF10033.4 KEZ38852.1 - 3.2e-62 210.0 0.0 5.1e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 SNF2_N PF00176.18 KEZ38853.1 - 6.5e-76 254.9 0.0 1.3e-75 253.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ38853.1 - 4.3e-13 48.9 0.0 1.1e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ38853.1 - 7.4e-06 25.5 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 KEZ38853.1 - 0.084 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 HDA2-3 PF11496.3 KEZ38853.1 - 0.92 8.2 7.2 0.072 11.8 0.1 2.5 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 DUF1754 PF08555.5 KEZ38853.1 - 3.4 8.3 21.1 0.32 11.6 8.5 3.0 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PEPCK_ATP PF01293.15 KEZ38854.1 - 4.6e-217 721.1 0.0 5.4e-217 720.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KEZ38854.1 - 0.0039 17.5 0.3 0.86 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEZ38854.1 - 0.087 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ38854.1 - 0.11 12.0 0.2 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MRFAP1 PF15155.1 KEZ38854.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 MORF4 family-associated protein1 AAA_16 PF13191.1 KEZ38854.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.22 KEZ38855.1 - 1.8e-44 151.4 0.0 3.2e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEZ38855.1 - 1.2e-20 73.4 0.6 2.6e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEZ38855.1 - 7.6e-07 29.1 0.2 1.8e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEZ38855.1 - 0.00012 21.9 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.4 KEZ38855.1 - 3.6 6.1 17.2 5.4 5.5 11.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med15 PF09606.5 KEZ38855.1 - 6.7 4.7 64.7 11 4.0 44.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ran-binding PF05508.6 KEZ38856.1 - 4.8e-105 350.7 0.0 6.5e-105 350.3 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein VHS PF00790.14 KEZ38857.1 - 2.2e-35 121.3 0.2 4.1e-35 120.4 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 KEZ38857.1 - 2.8e-16 58.8 0.2 5.6e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ38857.1 - 3e-16 58.5 0.0 6.6e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KEZ38857.1 - 1.2e-13 50.3 0.1 2.4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KEZ38857.1 - 0.1 12.2 5.6 0.28 10.8 3.9 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF4220 PF13968.1 KEZ38857.1 - 0.39 9.7 0.9 1.2 8.1 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4220) CK_II_beta PF01214.13 KEZ38858.1 - 3e-76 255.0 0.0 8.2e-76 253.6 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KEZ38858.1 - 0.011 16.3 8.8 0.011 16.3 6.1 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.6 KEZ38858.1 - 0.041 11.9 2.5 0.056 11.5 1.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.6 KEZ38858.1 - 0.12 10.1 0.6 0.18 9.6 0.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 KEZ38858.1 - 0.37 8.7 2.4 0.51 8.3 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 KEZ38858.1 - 1.6 8.2 8.9 2.9 7.4 6.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KEZ38858.1 - 2.4 8.5 11.6 6.6 7.1 5.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.13 KEZ38859.1 - 2.6e-13 49.4 0.1 5.7e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ38859.1 - 2.1e-07 30.7 12.1 3.6e-07 29.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.13 KEZ38860.1 - 7.7e-50 169.3 0.0 1.2e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KEZ38860.1 - 3.5e-22 78.4 0.0 6.6e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Sulfotransfer_3 PF13469.1 KEZ38861.1 - 0.002 19.0 0.2 0.0052 17.7 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family CitMHS PF03600.11 KEZ38862.1 - 0.0014 17.3 0.2 0.0023 16.5 0.2 1.4 1 1 0 1 1 1 1 Citrate transporter DUF4231 PF14015.1 KEZ38862.1 - 0.28 11.1 4.4 0.92 9.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MARVEL PF01284.18 KEZ38862.1 - 4 7.2 16.7 0.095 12.5 3.1 2.7 1 1 1 2 2 2 0 Membrane-associating domain Glyco_hydro_16 PF00722.16 KEZ38863.1 - 4.9e-18 65.0 0.2 2.6e-17 62.7 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 KEZ38863.1 - 0.0011 17.2 6.1 0.04 12.0 0.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF708 PF05341.6 KEZ38864.1 - 0.046 13.5 0.1 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF708) DUF3663 PF12404.3 KEZ38864.1 - 0.11 12.3 0.0 0.33 10.7 0.0 1.8 1 1 0 1 1 1 0 Peptidase HgmA PF04209.8 KEZ38865.1 - 1.1e-173 577.5 0.0 1.3e-173 577.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Methyltransf_23 PF13489.1 KEZ38866.1 - 3.2e-24 85.4 0.1 4.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ38866.1 - 7.7e-13 48.7 0.0 1.7e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ38866.1 - 4.2e-12 45.9 0.0 3.2e-11 43.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ38866.1 - 5.4e-12 46.2 0.0 4.2e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ38866.1 - 5.7e-11 42.7 0.0 1.7e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ38866.1 - 4e-08 33.5 0.0 1.1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ38866.1 - 1.2e-06 27.8 0.0 7.4e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 KEZ38866.1 - 0.00013 21.4 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KEZ38866.1 - 0.00019 21.4 0.0 0.002 18.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ38866.1 - 0.00044 19.6 0.0 0.0019 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KEZ38866.1 - 0.0011 18.0 0.0 0.029 13.4 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 KEZ38866.1 - 0.0041 16.3 0.0 0.0071 15.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 KEZ38866.1 - 0.0048 16.9 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 KEZ38866.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KEZ38866.1 - 0.03 13.4 0.0 0.058 12.5 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.13 KEZ38866.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Aldolase_II PF00596.16 KEZ38867.1 - 3.3e-29 101.8 0.7 4.5e-29 101.3 0.5 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.11 KEZ38868.1 - 1.1e-28 100.0 25.6 3.1e-28 98.4 18.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily RrnaAD PF00398.15 KEZ38869.1 - 3.4e-05 23.0 0.0 0.00044 19.3 0.0 2.3 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase An_peroxidase PF03098.10 KEZ38870.1 - 1.8e-96 323.6 0.0 1.5e-77 261.2 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KEZ38870.1 - 1.8e-05 23.4 0.0 4.5e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 AA_permease PF00324.16 KEZ38871.1 - 7.6e-99 331.2 32.4 9.1e-99 330.9 22.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ38871.1 - 4.5e-26 91.3 36.4 5.8e-26 90.9 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 KEZ38871.1 - 0.52 10.0 11.0 0.22 11.2 0.4 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) AMP-binding PF00501.23 KEZ38872.1 - 3.4e-63 213.5 0.0 1.1e-62 211.8 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ38872.1 - 1.7e-10 41.6 0.0 5.6e-10 40.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_61 PF03443.9 KEZ38873.1 - 1.5e-46 158.9 0.0 2.3e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Arginase PF00491.16 KEZ38874.1 - 1.2e-77 260.9 0.6 1.5e-77 260.6 0.4 1.1 1 0 0 1 1 1 1 Arginase family WW PF00397.21 KEZ38875.1 - 0.053 13.4 0.8 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 WW domain MARVEL PF01284.18 KEZ38876.1 - 2.7e-06 27.2 13.8 3.7e-06 26.8 9.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Hum_adeno_E3A PF05393.6 KEZ38876.1 - 4 7.1 10.2 0.06 13.0 0.6 2.6 2 1 1 3 3 3 0 Human adenovirus early E3A glycoprotein Microtub_assoc PF07989.6 KEZ38877.1 - 8.1e-19 67.2 10.3 8.1e-19 67.2 7.2 7.5 5 2 2 8 8 8 1 Microtubule associated Mto2_bdg PF12808.2 KEZ38877.1 - 9.1e-09 35.2 14.6 9.1e-09 35.2 10.1 12.5 12 1 1 13 13 13 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 KEZ38877.1 - 0.0017 17.6 2.6 0.0017 17.6 1.8 5.9 5 2 2 7 7 7 3 Reovirus sigma C capsid protein E1-E2_ATPase PF00122.15 KEZ38878.1 - 4.6e-60 202.5 1.1 4.6e-60 202.5 0.8 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ38878.1 - 6.6e-31 108.3 0.1 1.3e-26 94.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KEZ38878.1 - 1.3e-30 106.2 5.9 1.3e-30 106.2 4.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KEZ38878.1 - 5.3e-16 58.3 0.0 1.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ38878.1 - 2.7e-15 57.0 0.0 7e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ38878.1 - 3.5e-14 52.0 0.1 1e-13 50.5 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEZ38878.1 - 0.00062 19.4 0.1 0.0033 17.0 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.1 KEZ38878.1 - 0.4 10.4 4.8 1.5 8.6 0.7 2.9 2 0 0 2 2 2 0 CoA-binding domain DUF2697 PF10906.3 KEZ38879.1 - 0.16 11.9 0.3 0.54 10.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2697) AAA_16 PF13191.1 KEZ38880.1 - 8.1e-08 32.4 0.0 7.2e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.2 KEZ38880.1 - 5e-05 23.3 1.9 0.00016 21.6 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase family NACHT PF05729.7 KEZ38880.1 - 0.00036 20.2 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ38880.1 - 0.00074 19.6 0.0 0.0075 16.4 0.0 2.5 1 1 0 2 2 2 1 AAA domain Abhydrolase_5 PF12695.2 KEZ38880.1 - 0.0096 15.6 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_18 PF13238.1 KEZ38880.1 - 0.081 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ38880.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PGAP1 PF07819.8 KEZ38880.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 KEZ38880.1 - 0.16 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.17 KEZ38880.1 - 0.18 11.9 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase JAB PF01398.16 KEZ38881.1 - 9.6e-14 51.1 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KEZ38881.1 - 8.1e-07 28.5 0.0 2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 KEZ38881.1 - 0.00045 20.1 0.1 0.00077 19.4 0.1 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prefoldin_2 PF01920.15 KEZ38883.1 - 1.4e-22 79.4 12.2 1.8e-22 79.1 8.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 KEZ38883.1 - 0.0016 18.2 9.4 0.012 15.4 6.5 2.6 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KEZ38883.1 - 0.0019 17.8 12.0 0.014 14.9 0.5 2.9 2 1 1 3 3 3 1 Prefoldin subunit FlaC_arch PF05377.6 KEZ38883.1 - 0.0035 17.2 6.4 0.85 9.5 0.4 3.2 2 2 1 3 3 3 1 Flagella accessory protein C (FlaC) WEMBL PF05701.6 KEZ38883.1 - 0.0053 15.2 8.2 0.0072 14.8 5.7 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light PLC-beta_C PF08703.5 KEZ38883.1 - 0.0059 16.3 10.2 0.015 15.0 0.2 2.5 2 1 0 2 2 2 1 PLC-beta C terminal DUF4201 PF13870.1 KEZ38883.1 - 0.011 15.2 10.9 0.038 13.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1464 PF07318.7 KEZ38883.1 - 0.013 14.3 0.9 0.015 14.1 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Spc24 PF08286.6 KEZ38883.1 - 0.014 15.1 5.2 1.2 8.8 1.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 KEZ38883.1 - 0.014 14.0 10.1 0.017 13.7 7.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MscS_porin PF12795.2 KEZ38883.1 - 0.015 14.5 8.7 0.32 10.2 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain COG5 PF10392.4 KEZ38883.1 - 0.032 14.1 1.8 4.9 7.1 0.4 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3584 PF12128.3 KEZ38883.1 - 0.033 11.5 8.8 0.04 11.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RmuC PF02646.11 KEZ38883.1 - 0.04 12.7 7.5 0.69 8.6 0.4 2.1 1 1 1 2 2 2 0 RmuC family FliD_C PF07195.7 KEZ38883.1 - 0.043 13.1 5.7 0.18 11.0 3.9 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus NPV_P10 PF05531.7 KEZ38883.1 - 0.059 13.6 6.2 0.62 10.3 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_27 PF13514.1 KEZ38883.1 - 0.06 11.0 9.4 0.085 10.5 6.5 1.2 1 1 0 1 1 1 0 AAA domain Tektin PF03148.9 KEZ38883.1 - 0.069 11.6 10.5 0.52 8.7 0.3 2.0 2 0 0 2 2 2 0 Tektin family DUF4051 PF13260.1 KEZ38883.1 - 0.071 12.4 0.4 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) SpoOE-like PF09388.5 KEZ38883.1 - 0.076 12.5 1.2 0.12 11.9 0.1 1.8 2 0 0 2 2 1 0 Spo0E like sporulation regulatory protein Tropomyosin_1 PF12718.2 KEZ38883.1 - 0.08 12.7 14.5 0.7 9.7 5.0 2.1 2 0 0 2 2 2 0 Tropomyosin like IncA PF04156.9 KEZ38883.1 - 0.081 12.5 15.6 2.3 7.7 10.8 2.0 1 1 0 1 1 1 0 IncA protein Rho_Binding PF08912.6 KEZ38883.1 - 0.089 13.1 10.0 0.19 12.0 2.8 2.2 2 0 0 2 2 2 0 Rho Binding DivIC PF04977.10 KEZ38883.1 - 0.092 12.2 18.3 0.71 9.4 6.4 3.5 2 1 0 2 2 2 0 Septum formation initiator COG2 PF06148.6 KEZ38883.1 - 0.095 12.5 5.7 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.1 KEZ38883.1 - 0.12 11.4 14.5 0.89 8.7 10.1 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 KEZ38883.1 - 0.13 12.5 7.6 4.2 7.7 2.9 2.4 1 1 2 3 3 2 0 Snapin/Pallidin Kinetocho_Slk19 PF12709.2 KEZ38883.1 - 0.16 12.0 12.6 0.7 10.0 1.2 3.1 2 1 1 3 3 3 0 Central kinetochore-associated DUF1192 PF06698.6 KEZ38883.1 - 0.22 11.3 6.3 3.1 7.6 0.1 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF1192) Mnd1 PF03962.10 KEZ38883.1 - 0.23 11.1 12.6 0.9 9.1 7.0 2.0 1 1 1 2 2 2 0 Mnd1 family Hemagglutinin PF00509.13 KEZ38883.1 - 0.23 9.5 1.2 0.21 9.6 0.1 1.4 2 0 0 2 2 2 0 Haemagglutinin DUF4463 PF14703.1 KEZ38883.1 - 0.25 11.8 3.5 0.31 11.5 1.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) DUF677 PF05055.7 KEZ38883.1 - 0.29 9.7 4.2 0.59 8.7 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF677) CENP-F_leu_zip PF10473.4 KEZ38883.1 - 0.3 10.9 12.0 1.1 9.1 3.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med4 PF10018.4 KEZ38883.1 - 0.34 10.2 5.5 0.74 9.1 0.0 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIVA PF05103.8 KEZ38883.1 - 0.36 10.8 9.5 6.6 6.7 0.1 2.6 2 1 0 2 2 2 0 DivIVA protein HrpB7 PF09486.5 KEZ38883.1 - 0.42 10.5 5.8 6.3 6.6 0.6 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.8 KEZ38883.1 - 0.46 11.2 10.1 0.46 11.2 3.2 2.2 1 1 1 2 2 2 0 Occludin homology domain SbcD_C PF12320.3 KEZ38883.1 - 0.71 9.9 5.8 2.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Cep57_MT_bd PF06657.8 KEZ38883.1 - 0.74 9.8 10.3 1.4 8.9 2.7 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 KEZ38883.1 - 0.74 10.0 9.3 1.9 8.7 0.3 2.2 2 0 0 2 2 2 0 Syntaxin DUF1664 PF07889.7 KEZ38883.1 - 0.86 9.4 6.9 2.5 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NUDE_C PF04880.8 KEZ38883.1 - 0.89 9.9 7.6 0.62 10.4 2.6 2.3 2 1 1 3 3 3 0 NUDE protein, C-terminal conserved region Laminin_II PF06009.7 KEZ38883.1 - 0.89 9.3 7.0 5.9 6.6 0.1 2.3 2 1 0 2 2 2 0 Laminin Domain II Dor1 PF04124.7 KEZ38883.1 - 1 7.7 5.9 2 6.7 3.7 1.7 1 1 1 2 2 2 0 Dor1-like family DUF2046 PF09755.4 KEZ38883.1 - 1.1 8.1 11.9 1.7 7.4 2.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF848 PF05852.6 KEZ38883.1 - 1.2 8.9 6.7 3 7.6 1.9 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) YgaB PF14182.1 KEZ38883.1 - 1.3 9.2 14.6 0.096 12.9 1.6 2.2 2 0 0 2 2 2 0 YgaB-like protein T2SM PF04612.7 KEZ38883.1 - 1.3 8.7 7.2 6 6.6 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M BLOC1_2 PF10046.4 KEZ38883.1 - 1.5 9.0 7.5 5.5 7.1 1.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3847 PF12958.2 KEZ38883.1 - 1.6 8.5 9.6 1.7 8.4 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Laminin_I PF06008.9 KEZ38883.1 - 1.6 7.9 11.3 9.4 5.4 7.9 1.9 1 1 0 1 1 1 0 Laminin Domain I Rootletin PF15035.1 KEZ38883.1 - 1.9 8.4 13.1 16 5.3 9.1 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.7 KEZ38883.1 - 2 8.1 12.5 4 7.1 3.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 KEZ38883.1 - 2 7.9 13.0 3.7 7.0 9.0 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Golgin_A5 PF09787.4 KEZ38883.1 - 2.5 6.5 11.0 5.6 5.3 3.4 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF972 PF06156.8 KEZ38883.1 - 2.6 8.4 10.1 54 4.1 7.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4164 PF13747.1 KEZ38883.1 - 2.7 8.2 8.6 1.1 9.4 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) CCDC-167 PF15188.1 KEZ38883.1 - 2.7 8.0 7.3 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Sas10_Utp3 PF04000.10 KEZ38883.1 - 2.7 8.2 5.9 13 6.0 2.1 2.4 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Dzip-like_N PF13815.1 KEZ38883.1 - 2.7 7.8 10.4 1.9 8.3 3.3 2.2 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal TMF_DNA_bd PF12329.3 KEZ38883.1 - 2.8 7.8 14.2 8.3 6.2 4.1 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ERp29 PF07749.7 KEZ38883.1 - 3 8.5 6.0 37 5.0 4.1 2.3 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain End3 PF12761.2 KEZ38883.1 - 3 7.4 9.9 4.8 6.7 6.8 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Atg14 PF10186.4 KEZ38883.1 - 3.1 6.6 12.6 23 3.8 8.7 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 KEZ38883.1 - 3.2 6.9 4.5 4.7 6.4 1.0 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein FliJ PF02050.11 KEZ38883.1 - 3.3 7.7 15.5 6.8 6.7 1.1 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein bZIP_1 PF00170.16 KEZ38883.1 - 3.3 7.7 8.1 9.5 6.2 0.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor FemAB PF02388.11 KEZ38883.1 - 3.3 6.2 11.8 0.8 8.3 3.5 2.0 1 1 1 2 2 2 0 FemAB family Uds1 PF15456.1 KEZ38883.1 - 3.5 7.6 7.8 6.5 6.7 5.4 1.5 1 1 0 1 1 1 0 Up-regulated During Septation DUF904 PF06005.7 KEZ38883.1 - 3.5 7.9 15.0 9.3 6.6 10.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 KEZ38883.1 - 3.8 7.6 8.7 4.2 7.4 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ERM PF00769.14 KEZ38883.1 - 4.7 6.6 16.1 15 4.9 11.2 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Nup54 PF13874.1 KEZ38883.1 - 5.5 6.6 8.1 1.4 8.5 1.7 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Macoilin PF09726.4 KEZ38883.1 - 5.5 5.1 12.3 85 1.2 8.5 2.0 1 1 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 KEZ38883.1 - 5.9 5.7 12.0 13 4.6 4.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.7 KEZ38883.1 - 6.3 7.2 7.6 34 4.8 2.9 2.4 2 0 0 2 2 2 0 SlyX DUF1409 PF07197.7 KEZ38883.1 - 6.6 6.8 6.6 1.4 9.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Rab5-bind PF09311.6 KEZ38883.1 - 6.8 6.5 18.0 9.4 6.0 6.6 2.1 1 1 1 2 2 2 0 Rabaptin-like protein DUF3829 PF12889.2 KEZ38883.1 - 7.1 5.7 10.5 5.2 6.1 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) TMPIT PF07851.8 KEZ38883.1 - 7.4 5.5 8.0 18 4.2 5.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.1 KEZ38883.1 - 8.1 4.7 13.7 1.5 7.1 1.6 1.9 1 1 1 2 2 2 0 AAA domain Val_tRNA-synt_C PF10458.4 KEZ38883.1 - 8.5 6.5 10.1 6.7 6.8 0.2 3.3 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm TBPIP PF07106.8 KEZ38883.1 - 8.6 5.8 12.9 7.8 6.0 3.5 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) KID PF02524.9 KEZ38883.1 - 9.4 6.8 7.7 65 4.3 0.1 3.8 3 0 0 3 3 3 0 KID repeat AAA PF00004.24 KEZ38884.1 - 1.1e-41 142.0 0.0 2e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 KEZ38884.1 - 5.2e-20 71.0 7.0 1.1e-19 70.0 3.3 2.5 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.5 KEZ38884.1 - 4.3e-18 64.9 0.1 1.7e-17 63.0 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.1 KEZ38884.1 - 8.7e-06 26.5 0.1 3.2e-05 24.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KEZ38884.1 - 1.2e-05 25.3 0.2 0.00053 20.0 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.7 KEZ38884.1 - 2.3e-05 23.5 0.0 4.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEZ38884.1 - 4.4e-05 23.6 0.8 0.0032 17.6 0.1 2.8 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KEZ38884.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 KEZ38884.1 - 9e-05 22.4 0.0 0.0053 16.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEZ38884.1 - 0.00012 21.8 0.1 0.00048 19.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEZ38884.1 - 0.00012 21.9 0.0 0.00048 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEZ38884.1 - 0.00016 21.1 0.3 0.13 11.5 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 KEZ38884.1 - 0.0003 20.7 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEZ38884.1 - 0.00043 19.1 0.0 0.00085 18.1 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 KEZ38884.1 - 0.0011 18.0 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 KEZ38884.1 - 0.0035 17.6 0.3 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEZ38884.1 - 0.0053 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 KEZ38884.1 - 0.014 14.9 0.1 0.063 12.8 0.0 2.2 3 0 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.1 KEZ38884.1 - 0.024 14.6 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KEZ38884.1 - 0.026 14.1 0.0 0.98 9.0 0.0 2.4 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 KEZ38884.1 - 0.028 13.5 0.1 8.1 5.4 0.0 2.9 2 1 1 3 3 3 0 KaiC Mg_chelatase PF01078.16 KEZ38884.1 - 0.033 13.3 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEZ38884.1 - 0.035 13.2 0.1 0.15 11.1 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 KEZ38884.1 - 0.036 13.8 0.1 0.098 12.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 KEZ38884.1 - 0.044 12.6 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KEZ38884.1 - 0.086 12.5 0.7 0.26 10.9 0.0 2.1 2 1 0 2 2 2 0 Archaeal ATPase U79_P34 PF03064.11 KEZ38884.1 - 0.094 12.2 0.8 0.16 11.4 0.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PhoH PF02562.11 KEZ38884.1 - 0.097 11.8 0.1 0.23 10.6 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_21 PF13304.1 KEZ38884.1 - 0.22 11.4 1.2 4.4 7.1 0.0 2.5 2 1 0 3 3 3 0 AAA domain Nop PF01798.13 KEZ38885.1 - 4.3e-49 165.6 0.1 9.4e-49 164.5 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KEZ38885.1 - 9e-20 70.2 0.0 1.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KEZ38885.1 - 3.2e-14 52.8 0.0 1e-13 51.1 0.0 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain UPF0565 PF10561.4 KEZ38885.1 - 0.4 9.5 1.8 0.72 8.6 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RNA_polI_A34 PF08208.6 KEZ38885.1 - 2.3 7.8 17.1 4.2 6.9 11.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_hydro_18 PF00704.23 KEZ38886.1 - 3.7e-97 325.8 0.4 4.2e-97 325.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 KEZ38887.1 - 1.4e-34 117.2 0.9 2.7e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KEZ38887.1 - 1.6e-28 98.2 2.1 3.3e-28 97.2 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KEZ38887.1 - 4.8e-20 71.0 0.7 1e-19 69.9 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEZ38887.1 - 8.5e-06 25.9 0.4 3.9e-05 23.8 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KEZ38887.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KEZ38887.1 - 0.00069 19.4 0.5 0.0015 18.3 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEZ38887.1 - 0.0047 17.0 0.6 0.0063 16.6 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KEZ38887.1 - 0.058 13.4 0.6 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 KEZ38887.1 - 0.084 11.1 2.5 2 6.6 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 KEZ38887.1 - 0.11 12.3 0.4 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 IBR domain Ribosomal_S26e PF01283.14 KEZ38888.1 - 1.1e-50 170.6 6.2 1.2e-50 170.5 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 KEZ38888.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 KEZ38888.1 - 0.034 14.5 0.1 7.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 KEZ38888.1 - 0.049 14.0 0.9 1.1 9.7 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain TAP42 PF04177.7 KEZ38888.1 - 0.066 12.1 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family SMC_N PF02463.14 KEZ38889.1 - 4.5e-73 245.1 19.2 8.8e-73 244.1 13.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEZ38889.1 - 5.4e-28 97.3 0.0 2.1e-27 95.4 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEZ38889.1 - 1.1e-13 51.7 0.4 1.8e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEZ38889.1 - 0.00022 20.6 0.0 0.00048 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KEZ38889.1 - 0.00067 18.9 24.8 0.081 12.0 2.0 4.8 2 2 3 5 5 5 3 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 KEZ38889.1 - 0.0019 18.0 9.4 0.0019 18.0 6.5 7.4 4 3 3 7 7 7 1 Tropomyosin like Cep57_CLD_2 PF14197.1 KEZ38889.1 - 0.0063 16.4 2.6 0.0063 16.4 1.8 7.6 6 3 3 9 9 9 1 Centrosome localisation domain of PPC89 Laminin_II PF06009.7 KEZ38889.1 - 0.013 15.2 0.9 0.013 15.2 0.7 8.1 2 2 7 9 9 9 0 Laminin Domain II ELYS PF13934.1 KEZ38890.1 - 3.5e-63 213.3 0.6 4.1e-63 213.1 0.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF4360 PF14273.1 KEZ38892.1 - 5.2e-08 32.7 0.0 6.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NACHT PF05729.7 KEZ38893.1 - 2e-07 30.8 0.2 1e-06 28.4 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEZ38893.1 - 4.4e-05 23.5 0.0 0.00017 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PHD PF00628.24 KEZ38893.1 - 0.00076 19.1 5.1 0.0016 18.0 3.6 1.6 1 0 0 1 1 1 1 PHD-finger AAA PF00004.24 KEZ38893.1 - 0.0013 18.9 0.1 0.012 15.8 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ38893.1 - 0.0027 17.8 0.0 0.0093 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEZ38893.1 - 0.0068 16.6 0.1 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 KEZ38893.1 - 0.0081 15.6 0.1 0.052 12.9 0.1 2.2 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KEZ38893.1 - 0.017 14.2 0.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ38893.1 - 0.024 15.4 0.0 0.11 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ38893.1 - 0.038 13.5 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KEZ38893.1 - 0.045 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ38893.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KEZ38893.1 - 0.076 12.4 0.2 0.29 10.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain CUE PF02845.11 KEZ38895.1 - 3.2e-10 39.3 0.4 8.4e-10 37.9 0.0 2.0 2 0 0 2 2 2 1 CUE domain HWE_HK PF07536.9 KEZ38895.1 - 0.018 15.4 3.0 0.12 12.8 0.7 3.0 2 1 1 3 3 3 0 HWE histidine kinase Ribosomal_S10 PF00338.17 KEZ38896.1 - 3.2e-28 97.4 0.8 3.9e-28 97.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 KEZ38897.1 - 4.5e-07 29.3 3.8 8.5e-07 28.5 2.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 KEZ38897.1 - 0.00012 22.3 157.6 0.0012 19.0 15.5 6.6 1 1 1 3 3 3 1 Nucleoporin FG repeat region Med17 PF10156.4 KEZ38897.1 - 0.059 11.6 0.1 0.084 11.1 0.1 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex zf-CCCH_2 PF14608.1 KEZ38897.1 - 0.069 13.1 3.1 0.17 11.9 2.2 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Tachystatin_B PF11478.3 KEZ38897.1 - 7.6 6.3 7.6 0.81 9.4 0.5 3.0 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B Cellulase PF00150.13 KEZ38898.1 - 5e-19 68.5 0.4 9.3e-19 67.6 0.3 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Hpr_kinase_N PF02603.11 KEZ38898.1 - 0.15 11.7 0.1 0.32 10.7 0.0 1.6 1 1 0 1 1 1 0 HPr Serine kinase N terminus p450 PF00067.17 KEZ38899.1 - 6.8e-65 219.3 0.0 9.3e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Frag1 PF10277.4 KEZ38900.1 - 1.4e-38 132.5 5.2 1.4e-38 132.5 3.6 3.1 3 0 0 3 3 3 2 Frag1/DRAM/Sfk1 family Ank PF00023.25 KEZ38901.1 - 1.2e-120 387.8 16.0 3.4e-12 45.5 0.0 11.5 11 0 0 11 11 11 11 Ankyrin repeat Ank_2 PF12796.2 KEZ38901.1 - 1.7e-109 358.3 0.6 2.3e-22 79.1 0.0 6.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ38901.1 - 1.6e-88 281.6 7.4 2.4e-08 33.4 0.0 11.7 11 0 0 11 11 11 10 Ankyrin repeat Ank_4 PF13637.1 KEZ38901.1 - 1.4e-87 286.6 27.5 2.7e-13 50.0 0.0 10.2 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ38901.1 - 1e-83 273.4 29.3 7.3e-13 48.3 0.1 9.7 1 1 8 10 10 10 10 Ankyrin repeats (many copies) U3_assoc_6 PF08640.6 KEZ38901.1 - 1e-18 66.8 4.9 1.4e-15 56.7 0.2 3.8 3 1 0 4 4 4 2 U3 small nucleolar RNA-associated protein 6 NACHT PF05729.7 KEZ38901.1 - 0.00021 21.0 0.0 0.00059 19.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 KEZ38901.1 - 0.00043 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KEZ38901.1 - 0.0014 18.8 0.0 0.0099 16.0 0.0 2.5 3 0 0 3 3 2 1 AAA domain Abhydrolase_6 PF12697.2 KEZ38901.1 - 0.016 15.1 0.1 0.076 12.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L5 PF00281.14 KEZ38901.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L5 DUF1973 PF09315.6 KEZ38901.1 - 5.4 6.3 20.5 3.5 7.0 0.1 6.4 9 0 0 9 9 9 0 Domain of unknown function (DUF1973) Img2 PF05046.9 KEZ38902.1 - 6e-23 80.8 0.0 8.1e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 KEZ38903.1 - 7.6e-38 129.6 1.6 2e-37 128.3 1.1 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KEZ38903.1 - 1.3e-11 44.6 0.0 3.8e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 KEZ38903.1 - 0.0021 17.4 0.0 0.0046 16.3 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Apc1 PF12859.2 KEZ38904.1 - 1.4e-28 99.1 0.2 7.4e-28 96.8 0.1 2.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KEZ38904.1 - 3.2e-08 33.3 0.9 0.016 15.3 0.0 4.7 4 0 0 4 4 4 3 Proteasome/cyclosome repeat Clathrin PF00637.15 KEZ38905.1 - 1.2e-19 70.3 3.1 3.6e-18 65.5 1.5 3.2 2 2 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KEZ38905.1 - 2.3e-05 24.0 1.6 0.0095 15.8 0.4 3.5 3 1 0 3 3 2 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 KEZ38905.1 - 0.0016 18.1 0.5 0.003 17.2 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.4 KEZ38905.1 - 0.0057 16.6 0.7 0.019 14.9 0.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 NBP1 PF08537.5 KEZ38905.1 - 0.0097 15.1 0.2 0.019 14.1 0.1 1.4 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 TPR_7 PF13176.1 KEZ38905.1 - 0.029 14.1 1.7 0.077 12.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_phi PF04931.8 KEZ38905.1 - 0.048 11.4 16.1 0.072 10.8 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_2 PF13639.1 KEZ38905.1 - 0.064 13.0 1.1 0.13 12.1 0.7 1.5 1 0 0 1 1 1 0 Ring finger domain Pox_Ag35 PF03286.9 KEZ38905.1 - 0.65 9.4 12.9 0.16 11.4 4.3 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein VID27 PF08553.5 KEZ38905.1 - 1.8 6.7 10.0 3 5.9 6.9 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein RXT2_N PF08595.6 KEZ38905.1 - 3 7.6 11.3 9.8 5.9 7.8 1.9 1 0 0 1 1 1 0 RXT2-like, N-terminal FAD_binding_4 PF01565.18 KEZ38906.1 - 1.5e-19 69.8 0.1 4.3e-19 68.3 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ38906.1 - 4.4e-14 52.1 0.5 6.5e-13 48.3 0.2 2.5 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 KEZ38906.1 - 0.11 11.6 0.1 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Adeno_E3_CR2 PF02439.10 KEZ38908.1 - 7.2e-05 22.2 0.5 0.00013 21.4 0.4 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF202 PF02656.10 KEZ38908.1 - 0.0079 16.3 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Rifin_STEVOR PF02009.11 KEZ38908.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family SKG6 PF08693.5 KEZ38908.1 - 0.019 14.2 2.3 0.035 13.4 1.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 KEZ38908.1 - 0.028 14.0 0.6 0.049 13.2 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain MtrF PF09472.5 KEZ38908.1 - 0.58 9.4 3.4 1 8.6 2.4 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ASFV_J13L PF05568.6 KEZ38908.1 - 0.99 8.9 0.0 0.99 8.9 0.0 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein DEAD PF00270.24 KEZ38910.1 - 3.8e-43 146.8 0.0 5.5e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ38910.1 - 1.2e-23 82.6 0.1 2.4e-23 81.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain API5 PF05918.6 KEZ38910.1 - 0.085 11.3 5.9 0.13 10.7 4.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NUDIX PF00293.23 KEZ38911.1 - 5.1e-06 26.1 0.0 1.3e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain Fzo_mitofusin PF04799.8 KEZ38912.1 - 0.26 10.6 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 fzo-like conserved region Grp1_Fun34_YaaH PF01184.14 KEZ38912.1 - 0.8 8.9 2.5 1.1 8.4 1.7 1.1 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family bZIP_1 PF00170.16 KEZ38914.1 - 1.9e-07 30.8 11.9 3.3e-07 30.1 8.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ38914.1 - 7.6e-06 25.6 12.8 1.7e-05 24.5 8.8 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEZ38914.1 - 0.0071 16.6 6.6 0.013 15.8 4.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor CAF-1_p150 PF11600.3 KEZ38914.1 - 0.11 11.8 8.6 0.18 11.1 6.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2505 PF10698.4 KEZ38914.1 - 0.15 11.5 0.4 0.25 10.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) DUF4140 PF13600.1 KEZ38914.1 - 0.37 11.2 2.9 0.91 10.0 2.0 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SR-25 PF10500.4 KEZ38914.1 - 9.5 5.6 17.2 0.52 9.7 5.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WAP PF00095.16 KEZ38915.1 - 0.0032 17.3 3.1 0.0056 16.6 2.1 1.4 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Gamma-thionin PF00304.15 KEZ38915.1 - 0.022 14.7 3.2 0.035 14.1 2.3 1.3 1 0 0 1 1 1 0 Gamma-thionin family PepSY_2 PF13670.1 KEZ38915.1 - 0.26 11.2 2.7 9.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ank_2 PF12796.2 KEZ38917.1 - 1.4e-67 224.0 8.2 1e-16 61.0 0.1 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ38917.1 - 7.4e-48 158.0 17.4 7.9e-07 28.5 0.2 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KEZ38917.1 - 4.8e-42 141.6 6.4 5.7e-13 48.9 0.0 5.9 5 1 0 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ38917.1 - 4.1e-34 113.2 9.5 3.1e-05 23.8 0.1 9.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 KEZ38917.1 - 2.6e-32 110.1 16.9 1.2e-07 31.7 0.4 7.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) CorA PF01544.13 KEZ38917.1 - 6.4e-10 38.5 1.3 1.3e-09 37.5 0.9 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease_2 PF13520.1 KEZ38919.1 - 5.4e-83 278.8 30.0 6.8e-83 278.5 20.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ38919.1 - 1.2e-20 73.3 26.6 1.7e-20 72.8 18.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2206 PF09971.4 KEZ38919.1 - 0.081 11.7 1.6 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) AAA PF00004.24 KEZ38920.1 - 5.5e-08 33.0 0.0 1.6e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEZ38920.1 - 0.027 14.1 0.2 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KEZ38920.1 - 0.051 13.5 0.1 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain HET PF06985.6 KEZ38923.1 - 2.9e-35 121.4 0.0 4.7e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 KEZ38924.1 - 1.2e-42 146.0 0.1 1.6e-42 145.6 0.1 1.2 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KEZ38924.1 - 3.8e-09 36.9 0.0 7.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 KEZ38924.1 - 0.0076 15.9 0.0 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 PA domain p450 PF00067.17 KEZ38926.1 - 2.1e-53 181.5 0.0 2.6e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2423 PF10338.4 KEZ38926.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Methyltransf_23 PF13489.1 KEZ38927.1 - 2.1e-17 63.2 0.0 3.1e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ38927.1 - 8.4e-08 32.7 0.0 2.7e-06 27.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ38927.1 - 1.2e-06 28.9 0.0 2.6e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ38927.1 - 2.5e-05 24.6 0.0 6.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ38927.1 - 8.4e-05 22.1 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ38927.1 - 0.00056 19.3 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ38927.1 - 0.0015 18.5 0.1 0.0057 16.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ38927.1 - 0.0045 16.9 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KEZ38927.1 - 0.011 16.0 0.0 0.046 14.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEZ38927.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.7 KEZ38927.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 KEZ38927.1 - 0.15 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldo_ket_red PF00248.16 KEZ38928.1 - 1.5e-58 197.8 0.0 1.8e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CFEM PF05730.6 KEZ38929.1 - 1.8e-09 37.2 9.7 3.3e-09 36.4 6.7 1.4 1 0 0 1 1 1 1 CFEM domain Methyltransf_23 PF13489.1 KEZ38930.1 - 8.7e-09 35.2 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ38930.1 - 3.5e-06 26.7 0.0 9.6e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ38930.1 - 4.1e-05 23.9 0.0 6.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ38930.1 - 0.00033 21.0 0.0 0.0006 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ38930.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KEZ38930.1 - 0.038 14.5 0.0 0.16 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M19 PF01244.16 KEZ38931.1 - 1.2e-104 349.7 0.3 1.4e-104 349.5 0.2 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF4258 PF14076.1 KEZ38931.1 - 0.097 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) MFS_1 PF07690.11 KEZ38932.1 - 7.4e-37 126.8 53.9 4.8e-36 124.1 36.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily GST_C PF00043.20 KEZ38933.1 - 1e-08 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEZ38933.1 - 2.4e-05 24.7 0.0 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEZ38933.1 - 2.8e-05 24.0 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ38933.1 - 4.2e-05 23.6 0.0 8.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ38933.1 - 0.00022 21.0 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEZ38933.1 - 0.00057 19.9 0.0 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.16 KEZ38934.1 - 2.3e-27 95.8 0.0 6.6e-27 94.3 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class I and II Pyr_redox_2 PF07992.9 KEZ38934.1 - 1.2e-20 74.2 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ38934.1 - 8.6e-06 24.4 0.1 0.0048 15.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 KEZ38934.1 - 1.1e-05 24.5 0.2 0.00011 21.2 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ38934.1 - 3.2e-05 24.0 0.0 0.3 11.1 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ38934.1 - 5.5e-05 22.1 0.1 0.00012 21.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KEZ38934.1 - 0.00014 21.6 0.2 0.13 12.0 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 KEZ38934.1 - 0.00083 18.3 0.1 0.092 11.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KEZ38934.1 - 0.0011 18.1 0.1 0.0017 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ38934.1 - 0.0021 18.0 0.1 0.0046 16.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ38934.1 - 0.029 13.4 0.0 0.063 12.3 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Beta_elim_lyase PF01212.16 KEZ38934.1 - 0.098 11.7 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase GIDA PF01134.17 KEZ38934.1 - 0.11 11.3 0.0 0.83 8.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KEZ38934.1 - 0.18 10.7 0.1 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein BNR_2 PF13088.1 KEZ38935.1 - 7.4e-05 22.1 0.8 0.013 14.8 0.1 2.2 1 1 0 2 2 2 2 BNR repeat-like domain Esterase_phd PF10503.4 KEZ38937.1 - 4.9e-22 78.2 0.3 6.7e-22 77.8 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEZ38937.1 - 7.1e-10 38.4 0.3 9.6e-10 38.0 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ38937.1 - 3.9e-05 23.4 0.1 5.3e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KEZ38937.1 - 0.002 16.9 0.1 0.0027 16.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ38937.1 - 0.0035 16.9 0.1 0.0081 15.7 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KEZ38937.1 - 0.028 13.8 0.3 0.044 13.2 0.2 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KEZ38937.1 - 0.033 13.7 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ38937.1 - 0.041 13.7 0.2 0.098 12.5 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 KEZ38938.1 - 0.0005 19.5 0.1 0.0013 18.1 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KEZ38938.1 - 0.0031 16.9 0.2 0.0071 15.8 0.2 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 KEZ38938.1 - 0.0043 16.3 0.2 0.0068 15.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 KEZ38938.1 - 0.026 13.7 0.9 0.04 13.1 0.0 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KEZ38938.1 - 0.065 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ38938.1 - 0.082 12.7 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family APH PF01636.18 KEZ38939.1 - 4.7e-05 23.2 0.1 8.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ38939.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Tyrosinase PF00264.15 KEZ38940.1 - 8.9e-44 150.2 0.0 1.4e-43 149.6 0.0 1.3 1 1 0 1 1 1 1 Common central domain of tyrosinase zf-B_box PF00643.19 KEZ38941.1 - 0.0001 22.1 1.7 0.0001 22.1 1.2 2.5 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_3 PF13920.1 KEZ38941.1 - 0.0056 16.3 0.7 0.0056 16.3 0.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.18 KEZ38941.1 - 0.13 12.1 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 KEZ38941.1 - 0.14 12.6 0.0 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein zf-C3HC4_2 PF13923.1 KEZ38941.1 - 0.14 12.2 14.0 0.28 11.2 1.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 KEZ38941.1 - 0.62 9.5 9.0 1.5 8.3 0.4 2.7 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.1 KEZ38941.1 - 0.72 9.6 11.5 0.057 13.1 0.4 2.6 2 0 0 2 2 2 0 zinc-RING finger domain CorA PF01544.13 KEZ38942.1 - 3.1e-08 33.0 0.2 2.5e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SGL PF08450.7 KEZ38943.1 - 0.0026 17.1 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Protoglobin PF11563.3 KEZ38944.1 - 3.1e-55 186.1 0.0 3.7e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Protoglobin MFS_1 PF07690.11 KEZ38945.1 - 1.9e-20 72.9 28.4 1.9e-20 72.9 19.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily NIR_SIR PF01077.17 KEZ38946.1 - 8.4e-26 90.2 0.0 1.6e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KEZ38946.1 - 1.4e-22 80.5 0.1 2.2e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KEZ38946.1 - 2.4e-17 62.5 0.0 5.7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 KEZ38946.1 - 6.1e-15 55.3 2.7 4.6e-13 49.3 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KEZ38946.1 - 2.9e-12 46.0 0.8 5.7e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 KEZ38946.1 - 1.9e-10 40.1 0.0 4.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Fer2_BFD PF04324.10 KEZ38946.1 - 6.2e-09 35.7 0.4 2.3e-08 33.9 0.3 2.0 1 1 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Pyr_redox_3 PF13738.1 KEZ38946.1 - 0.0005 20.1 0.0 0.18 11.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ38946.1 - 0.0032 17.2 0.1 6.8 6.4 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding Mo-co_dimer PF03404.11 KEZ38947.1 - 6.6e-54 181.0 0.0 1.1e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KEZ38947.1 - 7.3e-47 158.9 0.0 1.3e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KEZ38947.1 - 5.1e-27 93.8 0.0 1e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEZ38947.1 - 4.2e-24 85.2 0.0 9.6e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KEZ38947.1 - 2.9e-21 75.0 0.0 5.3e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KEZ38947.1 - 0.0024 17.7 0.0 0.0062 16.4 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Asp PF00026.18 KEZ38948.1 - 3e-39 135.1 6.4 6.9e-39 133.9 4.4 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ38948.1 - 3.2e-06 27.2 1.1 3.2e-06 27.2 0.8 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Shisa PF13908.1 KEZ38948.1 - 1.4 9.0 5.5 4 7.5 3.8 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 KEZ38949.1 - 1.3e-21 76.7 27.9 7.2e-14 51.2 6.0 3.0 2 2 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.15 KEZ38949.1 - 7.2e-05 21.0 1.0 0.00013 20.2 0.7 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family FPN1 PF06963.7 KEZ38949.1 - 0.06 11.7 0.1 0.06 11.7 0.0 1.8 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Oxidored_q6 PF01058.17 KEZ38950.1 - 2.3e-22 79.0 0.1 2.9e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Ank_2 PF12796.2 KEZ38951.1 - 7.9e-41 138.2 11.1 5.5e-19 68.2 0.7 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ38951.1 - 8.8e-31 104.1 10.8 2.8e-09 36.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 KEZ38951.1 - 3.6e-25 87.8 5.6 6.3e-11 42.4 0.1 6.7 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ38951.1 - 1.1e-18 65.4 11.6 7.3e-05 22.6 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KEZ38951.1 - 3e-17 62.2 13.8 5.5e-07 29.6 0.9 6.0 3 1 3 6 6 6 6 Ankyrin repeats (many copies) HET PF06985.6 KEZ38952.1 - 0.0035 17.4 0.3 0.96 9.5 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF883 PF05957.8 KEZ38955.1 - 0.013 15.8 0.4 0.085 13.2 0.3 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MCR_alpha_N PF02745.10 KEZ38955.1 - 0.066 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Zn_clus PF00172.13 KEZ38956.1 - 1.9e-07 30.8 9.1 3e-07 30.2 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ38956.1 - 8.2e-05 21.5 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ38957.1 - 2.9e-27 95.2 13.9 2.9e-27 95.2 9.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidohydro_2 PF04909.9 KEZ38958.1 - 6e-12 45.6 0.0 8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Mito_carr PF00153.22 KEZ38959.1 - 8.1e-27 92.7 5.9 1.4e-10 40.7 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Aconitase PF00330.15 KEZ38960.1 - 4.2e-63 213.4 0.1 2.7e-62 210.7 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEZ38960.1 - 7.1e-43 145.8 0.0 1.2e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_6 PF03737.10 KEZ38961.1 - 1.6e-29 102.7 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Sugar_tr PF00083.19 KEZ38962.1 - 4.4e-77 259.5 17.5 5.3e-77 259.2 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ38962.1 - 7.1e-17 61.1 14.2 7.1e-17 61.1 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dabb PF07876.7 KEZ38963.1 - 2.6e-12 47.0 0.4 4.4e-12 46.2 0.3 1.4 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain CAF1A PF12253.3 KEZ38963.1 - 0.0059 16.6 0.5 0.019 15.0 0.3 1.9 1 1 0 1 1 1 1 Chromatin assembly factor 1 subunit A Dak1 PF02733.12 KEZ38964.1 - 1e-97 326.6 0.2 1.6e-97 326.0 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KEZ38964.1 - 2.5e-42 144.4 3.0 3.7e-42 143.9 2.1 1.3 1 0 0 1 1 1 1 DAK2 domain Fungal_trans PF04082.13 KEZ38965.1 - 5.8e-21 74.5 0.0 1.1e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SSP160 PF06933.6 KEZ38965.1 - 0.23 9.4 0.4 0.33 8.8 0.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ldh_2 PF02615.9 KEZ38966.1 - 2.6e-94 315.6 0.0 4.1e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase F_bP_aldolase PF01116.15 KEZ38966.1 - 3.1e-87 292.3 0.0 1.4e-86 290.1 0.0 2.0 3 0 0 3 3 3 1 Fructose-bisphosphate aldolase class-II Esterase_phd PF10503.4 KEZ38968.1 - 3e-09 36.4 0.1 4.1e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEZ38968.1 - 1.5e-06 27.6 0.1 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KEZ38968.1 - 0.036 12.7 0.1 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Pyr_redox_3 PF13738.1 KEZ38969.1 - 2e-20 73.6 0.0 6.4e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ38969.1 - 1.1e-17 63.4 0.1 2.2e-12 45.9 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ38969.1 - 3.1e-10 39.5 0.0 7.4e-06 25.1 0.0 3.9 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEZ38969.1 - 1.8e-08 34.2 0.0 5e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEZ38969.1 - 0.025 14.3 1.8 0.76 9.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KEZ38969.1 - 0.037 14.4 3.4 0.16 12.3 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ38969.1 - 0.044 12.6 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KEZ38969.1 - 0.059 12.4 1.1 0.17 10.9 0.0 2.2 3 0 0 3 3 3 0 Thi4 family DAO PF01266.19 KEZ38969.1 - 0.094 11.5 0.0 0.84 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 KEZ38970.1 - 2.3e-25 88.9 0.2 4.3e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KEZ38971.1 - 5e-26 91.5 0.2 7.5e-26 91.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.11 KEZ38971.1 - 6.3e-19 67.8 20.2 1.3e-18 66.8 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 KEZ38971.1 - 2e-18 67.0 0.1 3.3e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ38971.1 - 1.2e-12 47.8 0.1 2e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ38971.1 - 0.00057 19.3 0.1 0.0012 18.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEZ38971.1 - 0.0054 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KEZ38971.1 - 0.048 12.7 0.0 0.32 10.0 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.20 KEZ38972.1 - 5.5e-24 84.9 0.0 9.4e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ38972.1 - 1.7e-09 37.5 0.0 3.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ38972.1 - 3.3e-08 33.5 0.0 5.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEZ38972.1 - 0.00065 19.1 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_26 PF13659.1 KEZ38972.1 - 0.1 12.6 0.2 7.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_3 PF07859.8 KEZ38973.1 - 1.3e-43 149.0 0.0 1.6e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEZ38973.1 - 1.3e-05 24.1 0.2 2.3e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEZ38973.1 - 0.00017 21.3 0.1 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KEZ38973.1 - 0.0068 15.0 0.0 0.0091 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DLH PF01738.13 KEZ38973.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KEZ38973.1 - 0.019 14.2 0.0 0.038 13.2 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family TauD PF02668.11 KEZ38974.1 - 1.8e-44 152.3 0.2 2.3e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PfkB PF00294.19 KEZ38976.1 - 1.5e-18 66.9 0.1 5e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase E1-E2_ATPase PF00122.15 KEZ38977.1 - 2.1e-38 131.6 5.7 1.5e-23 83.0 0.0 2.3 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 KEZ38977.1 - 3.6e-28 99.4 0.0 4e-27 96.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ38977.1 - 4.6e-19 68.1 0.0 1.9e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ38977.1 - 2.3e-16 60.5 0.0 4.5e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ38977.1 - 1.2e-15 56.6 0.1 3.9e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 KEZ38977.1 - 1.8e-15 56.9 0.1 1.8e-15 56.9 0.0 2.7 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus DUF1469 PF07332.6 KEZ38977.1 - 0.0003 20.5 4.6 0.043 13.5 0.9 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1469) Hydrolase_3 PF08282.7 KEZ38977.1 - 0.0062 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CorA PF01544.13 KEZ38978.1 - 6.4e-11 41.8 1.2 2.3e-10 40.0 0.0 2.4 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein EMP70 PF02990.11 KEZ38978.1 - 0.25 9.7 1.5 0.35 9.2 1.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 MFS_1 PF07690.11 KEZ38979.1 - 4.8e-29 101.1 46.1 4.8e-29 101.1 32.0 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ38979.1 - 1.4e-08 33.3 9.0 2.8e-08 32.4 5.9 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KEZ38979.1 - 1.3 6.9 11.8 0.29 9.1 1.5 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.13 KEZ38980.1 - 5e-05 23.1 9.1 9e-05 22.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-FPG_IleRS PF06827.9 KEZ38980.1 - 1.2 8.8 6.2 2.8 7.6 4.3 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS GMC_oxred_N PF00732.14 KEZ38981.1 - 6.6e-54 183.0 0.0 9.5e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ38981.1 - 3e-35 121.6 0.0 5.7e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ38981.1 - 7.4e-07 28.3 0.0 0.00088 18.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ38981.1 - 8e-06 24.9 0.6 0.0034 16.3 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ38981.1 - 0.0021 18.0 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ38981.1 - 0.0021 18.1 0.2 0.086 12.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ38981.1 - 0.0023 17.8 0.0 0.13 12.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ38981.1 - 0.0031 16.4 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEZ38981.1 - 0.0084 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.13 KEZ38981.1 - 0.031 14.2 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 KEZ38981.1 - 0.04 13.6 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF4147 PF13660.1 KEZ38981.1 - 0.052 12.6 0.1 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Tyrosinase PF00264.15 KEZ38982.1 - 1.5e-46 159.3 1.6 1.5e-46 159.3 1.1 3.0 2 1 0 2 2 2 1 Common central domain of tyrosinase DUF3333 PF11812.3 KEZ38983.1 - 0.0048 16.9 0.1 0.0048 16.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3333) Tropomyosin_1 PF12718.2 KEZ38983.1 - 0.14 12.0 45.0 0.31 10.8 6.7 2.4 2 0 0 2 2 2 0 Tropomyosin like Prominin PF05478.6 KEZ38983.1 - 0.33 8.4 3.5 0.082 10.4 0.0 1.5 2 0 0 2 2 2 0 Prominin Mnd1 PF03962.10 KEZ38983.1 - 0.48 10.0 29.5 0.51 9.9 3.7 2.4 2 0 0 2 2 2 0 Mnd1 family DUF3632 PF12311.3 KEZ38985.1 - 1.2e-28 100.1 0.5 1.6e-28 99.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 KEZ38986.1 - 7.8e-18 64.3 0.1 1.2e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 ribonuclease Glyco_hydro_7 PF00840.15 KEZ38987.1 - 8.3e-191 634.0 17.9 9.8e-191 633.7 12.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Sulfate_transp PF00916.15 KEZ38988.1 - 5.5e-81 271.6 13.1 8.5e-81 271.0 9.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEZ38988.1 - 2.3e-29 100.8 4.0 2.3e-29 100.8 2.8 3.2 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEZ38988.1 - 5.2e-10 38.7 0.0 1.5e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 KEZ38988.1 - 0.00087 19.2 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 STAS domain 2-Hacid_dh_C PF02826.14 KEZ38989.1 - 1.9e-43 147.6 0.0 7.9e-30 103.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEZ38989.1 - 0.00041 19.8 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Gp_dh_N PF00044.19 KEZ38989.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sulfotransfer_3 PF13469.1 KEZ38990.1 - 0.0013 19.7 3.8 0.0044 17.9 2.6 1.8 1 1 0 1 1 1 1 Sulfotransferase family DUF2150 PF09920.4 KEZ38992.1 - 0.12 11.9 0.7 0.15 11.6 0.3 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) DUF2383 PF09537.5 KEZ38992.1 - 0.16 12.2 0.8 0.24 11.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF4398 PF14346.1 KEZ38992.1 - 1.8 8.6 13.5 3.2 7.8 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) Rotamase_2 PF13145.1 KEZ38992.1 - 4.2 8.0 6.1 1.2 9.7 2.4 1.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain Glyco_hydro_71 PF03659.9 KEZ38993.1 - 3.1e-140 467.0 3.1 4.1e-140 466.6 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Lipase_GDSL_2 PF13472.1 KEZ38993.1 - 4.6e-10 39.9 0.0 8.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ38993.1 - 0.0026 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NYN PF01936.13 KEZ38994.1 - 0.00049 20.4 0.0 0.00096 19.4 0.0 1.4 1 0 0 1 1 1 1 NYN domain DUF1648 PF07853.6 KEZ38996.1 - 0.059 12.8 0.4 0.094 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Cut8_N PF14482.1 KEZ38996.1 - 0.059 13.3 3.3 0.11 12.5 2.3 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Cellulase PF00150.13 KEZ38997.1 - 1.6e-52 178.4 0.4 2.1e-52 178.0 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF924 PF06041.6 KEZ38999.1 - 3.3e-45 154.1 0.2 4.5e-45 153.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DUF4066 PF13278.1 KEZ39000.1 - 7e-15 54.6 0.0 1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEZ39000.1 - 0.00022 20.7 0.0 0.00042 19.8 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family MFS_1 PF07690.11 KEZ39001.1 - 1.3e-41 142.4 53.9 2e-41 141.9 37.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.10 KEZ39002.1 - 4.2e-46 155.5 3.7 1e-45 154.2 0.6 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 KEZ39002.1 - 2.8e-31 108.5 0.0 3.1e-30 105.1 0.0 2.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEZ39002.1 - 3.9e-30 104.1 3.6 9.1e-23 80.2 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase Erythro-docking PF09277.6 KEZ39002.1 - 0.054 13.1 0.2 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 Erythronolide synthase, docking YjgP_YjgQ PF03739.9 KEZ39002.1 - 0.15 10.7 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Lipocalin PF00061.18 KEZ39004.1 - 0.0039 17.1 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family NACHT PF05729.7 KEZ39004.1 - 0.0098 15.5 0.1 0.54 9.8 0.0 2.6 1 1 1 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ39004.1 - 0.011 15.8 0.0 0.036 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEZ39004.1 - 0.052 12.9 0.0 3.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 KEZ39004.1 - 0.074 12.5 0.8 0.15 11.6 0.6 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KEZ39004.1 - 0.092 12.6 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ39004.1 - 0.13 12.4 0.1 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KEZ39004.1 - 0.17 11.5 0.0 0.81 9.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase GP41 PF00517.12 KEZ39004.1 - 4.1 6.9 6.5 0.49 9.9 1.3 1.8 2 0 0 2 2 2 0 Retroviral envelope protein NACHT PF05729.7 KEZ39005.1 - 3.3e-08 33.3 0.1 6.3e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 KEZ39005.1 - 6.5e-08 31.8 0.0 2.4e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily KaiC PF06745.8 KEZ39005.1 - 1.2e-07 31.1 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 KEZ39005.1 - 2.8e-06 27.4 1.5 5.5e-06 26.5 0.0 2.2 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 KEZ39005.1 - 9.4e-06 25.7 0.1 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 KEZ39005.1 - 1.5e-05 24.8 0.2 0.00038 20.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KEZ39005.1 - 0.00052 18.9 0.0 0.0011 17.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KEZ39005.1 - 0.0013 18.4 0.1 0.0032 17.2 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase DUF2075 PF09848.4 KEZ39005.1 - 0.0098 14.8 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KEZ39005.1 - 0.041 14.0 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ39005.1 - 0.054 14.3 0.2 0.19 12.5 0.0 2.0 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 KEZ39005.1 - 0.078 11.9 0.3 9.4 5.1 0.1 2.8 2 1 1 3 3 3 0 KAP family P-loop domain SAS4 PF15460.1 KEZ39005.1 - 0.54 10.1 4.3 8.6 6.2 0.2 2.5 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 HSP70 PF00012.15 KEZ39006.1 - 1.6e-05 23.0 0.1 0.029 12.3 0.0 3.0 3 0 0 3 3 3 3 Hsp70 protein Spc42p PF11544.3 KEZ39007.1 - 0.1 12.5 0.1 0.36 10.7 0.1 1.9 2 0 0 2 2 2 0 Spindle pole body component Spc42p Linker_histone PF00538.14 KEZ39008.1 - 2.1e-22 78.9 0.3 3.9e-22 78.1 0.2 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family Pro_CA PF00484.14 KEZ39010.1 - 2.1e-21 76.5 0.0 3.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase ABC2_membrane PF01061.19 KEZ39012.1 - 7.4e-81 270.3 58.9 1e-42 145.7 13.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEZ39012.1 - 5.3e-37 127.1 0.0 1e-17 64.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEZ39012.1 - 9.6e-30 102.3 2.3 8e-25 86.4 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KEZ39012.1 - 6.3e-13 48.4 33.9 8.9e-07 28.2 14.2 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KEZ39012.1 - 2.3e-07 30.3 0.6 0.00093 18.6 0.0 3.4 4 0 0 4 4 4 2 AAA domain ABC_trans_N PF14510.1 KEZ39012.1 - 5.5e-07 29.5 0.0 2.1e-06 27.7 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 KEZ39012.1 - 5.6e-06 25.7 0.1 0.0041 16.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ39012.1 - 7.9e-06 26.6 0.0 0.029 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEZ39012.1 - 8.5e-06 25.7 0.0 0.027 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KEZ39012.1 - 1.4e-05 25.2 0.0 0.065 13.1 0.0 2.7 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ39012.1 - 2e-05 24.6 0.4 0.0099 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 KEZ39012.1 - 5.6e-05 23.1 0.4 0.031 14.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 KEZ39012.1 - 0.0001 22.4 0.0 0.24 11.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEZ39012.1 - 0.0001 21.9 1.0 0.099 12.4 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain UPF0079 PF02367.12 KEZ39012.1 - 0.00035 20.2 1.9 0.62 9.6 0.1 3.0 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KEZ39012.1 - 0.001 18.3 0.0 0.0054 15.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEZ39012.1 - 0.0011 19.2 0.0 0.38 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEZ39012.1 - 0.0032 17.1 0.5 1.8 8.2 0.0 2.4 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 KEZ39012.1 - 0.0033 16.6 0.1 0.17 11.0 0.0 3.2 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KEZ39012.1 - 0.0034 16.8 2.5 0.11 11.9 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 KEZ39012.1 - 0.0098 16.0 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KEZ39012.1 - 0.012 15.9 0.0 0.63 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEZ39012.1 - 0.025 15.0 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KEZ39012.1 - 0.039 13.3 0.2 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 KEZ39012.1 - 0.046 13.2 0.8 2.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MHC2-interact PF09307.5 KEZ39012.1 - 0.047 13.4 0.3 19 5.0 0.0 3.5 3 0 0 3 3 3 0 CLIP, MHC2 interacting FtsK_SpoIIIE PF01580.13 KEZ39012.1 - 0.052 13.0 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KEZ39012.1 - 0.068 12.7 0.5 9.2 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 KEZ39012.1 - 0.35 9.8 0.0 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Myosin_head PF00063.16 KEZ39013.1 - 1.1e-243 810.3 0.4 1.1e-243 810.3 0.3 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KEZ39013.1 - 1.8e-17 63.1 2.2 2.1e-17 62.8 0.1 2.2 2 0 0 2 2 1 1 DIL domain IQ PF00612.22 KEZ39013.1 - 2.7e-12 45.1 35.7 3.5e-05 23.0 0.4 7.0 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_22 PF13401.1 KEZ39013.1 - 0.0035 17.4 3.7 0.0048 17.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Baculo_PEP_C PF04513.7 KEZ39013.1 - 0.0089 15.8 7.8 0.017 14.9 4.1 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_N PF02736.14 KEZ39013.1 - 0.02 14.5 0.0 0.054 13.1 0.0 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KEZ39013.1 - 0.025 14.3 0.2 0.099 12.4 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_16 PF13191.1 KEZ39013.1 - 0.026 14.5 2.6 0.07 13.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 KEZ39013.1 - 0.11 11.9 0.0 0.11 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain GAS PF13851.1 KEZ39013.1 - 0.28 10.3 27.9 1.3 8.1 19.4 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 KEZ39013.1 - 0.38 10.6 7.5 1.2 9.0 0.1 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF812 PF05667.6 KEZ39013.1 - 0.55 8.6 27.0 0.88 8.0 18.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KEZ39013.1 - 1.9 7.5 6.1 2.3 7.3 1.2 2.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 KEZ39013.1 - 2.6 7.0 27.7 0.78 8.7 16.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 2-Hacid_dh_C PF02826.14 KEZ39014.1 - 2e-52 176.9 0.0 3.7e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEZ39014.1 - 1.2e-34 118.5 0.0 1.8e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEZ39014.1 - 1.8e-05 24.6 0.6 7.3e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 KEZ39014.1 - 0.005 16.6 0.2 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 KEZ39014.1 - 0.0063 15.8 0.1 0.086 12.2 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 KEZ39014.1 - 0.0092 15.4 0.2 0.031 13.7 0.1 1.9 1 1 0 1 1 1 1 ACT domain NAP PF00956.13 KEZ39015.1 - 1.7e-87 292.6 8.2 1.7e-87 292.6 5.7 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) HAD PF12710.2 KEZ39016.1 - 1.7e-29 103.3 0.0 5.8e-29 101.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEZ39016.1 - 3e-25 88.6 0.0 5.7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ39016.1 - 5.3e-19 69.4 0.0 5.5e-18 66.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KEZ39016.1 - 0.00017 21.4 0.0 0.00048 19.9 0.0 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.21 KEZ39016.1 - 0.0038 16.6 0.0 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEZ39016.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEZ39016.1 - 0.092 12.3 0.0 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CMAS PF02353.15 KEZ39017.1 - 2.3e-34 118.7 0.0 3.3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UQ_con PF00179.21 KEZ39017.1 - 1.5e-20 73.0 0.0 2.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Methyltransf_31 PF13847.1 KEZ39017.1 - 7e-18 64.6 0.0 1.1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39017.1 - 1.3e-17 64.0 0.0 2.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ39017.1 - 1.7e-14 53.8 0.0 3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39017.1 - 8.8e-12 45.5 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39017.1 - 7.6e-11 42.3 0.0 1.4e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ39017.1 - 4.8e-08 33.2 0.0 3.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ39017.1 - 5.4e-07 28.9 0.0 8.3e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ39017.1 - 7.9e-07 28.5 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KEZ39017.1 - 0.00026 20.0 0.0 0.00066 18.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase GidB PF02527.10 KEZ39017.1 - 0.00057 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.14 KEZ39017.1 - 0.00078 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 KEZ39017.1 - 0.0021 17.6 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.9 KEZ39017.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 KEZ39017.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RWD PF05773.17 KEZ39017.1 - 0.039 13.8 0.0 0.069 13.0 0.0 1.5 1 1 0 1 1 1 0 RWD domain RrnaAD PF00398.15 KEZ39017.1 - 0.051 12.5 0.1 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.8 KEZ39017.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Pex14_N PF04695.8 KEZ39017.1 - 0.11 12.5 2.0 0.21 11.6 1.0 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DREV PF05219.7 KEZ39017.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AA_permease PF00324.16 KEZ39018.1 - 6.3e-52 176.4 30.4 9.1e-52 175.9 21.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ39018.1 - 3.1e-17 62.2 36.0 4.3e-17 61.7 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4229 PF14012.1 KEZ39018.1 - 0.0035 17.2 2.8 0.0035 17.2 1.9 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF4229) SKIP_SNW PF02731.10 KEZ39019.1 - 7.5e-66 220.4 3.3 7.5e-66 220.4 2.3 3.0 3 0 0 3 3 3 1 SKIP/SNW domain EMP24_GP25L PF01105.19 KEZ39019.1 - 1.4e-44 151.9 1.3 2.7e-44 151.0 0.9 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhoD PF09423.5 KEZ39020.1 - 8e-55 186.1 0.0 1.1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase TauD PF02668.11 KEZ39021.1 - 1.1e-35 123.6 0.0 1.3e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Metallophos PF00149.23 KEZ39022.1 - 1.9e-41 141.7 1.4 2.9e-41 141.0 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase B-block_TFIIIC PF04182.7 KEZ39023.1 - 6.7e-12 45.0 0.0 5.5e-11 42.1 0.0 2.4 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC OxoDH_E1alpha_N PF12573.3 KEZ39024.1 - 0.036 13.6 0.7 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Dynamin_N PF00350.18 KEZ39025.1 - 7.1e-44 149.5 0.4 4.8e-43 146.8 0.0 2.2 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEZ39025.1 - 3.9e-08 32.4 0.0 6.5e-07 28.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KEZ39025.1 - 0.0011 18.8 0.0 0.0037 17.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ39025.1 - 0.0029 18.0 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 KEZ39025.1 - 0.082 12.8 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cation_efflux PF01545.16 KEZ39026.1 - 2.6e-34 118.6 8.4 3.1e-34 118.3 5.8 1.0 1 0 0 1 1 1 1 Cation efflux family Ebp2 PF05890.7 KEZ39027.1 - 5.4e-91 304.6 18.3 5.4e-91 304.6 12.7 2.3 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 GATase_4 PF13230.1 KEZ39030.1 - 1.6e-17 63.1 0.0 2.1e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KEZ39030.1 - 1e-08 35.2 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KEZ39030.1 - 4.9e-07 28.7 0.1 0.00011 21.1 0.1 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Mito_carr PF00153.22 KEZ39031.1 - 3.3e-68 225.4 0.8 1.8e-24 85.2 0.0 4.2 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KEZ39031.1 - 1.4e-16 58.4 3.4 9.7e-07 27.6 0.1 5.5 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 KEZ39031.1 - 3e-16 57.7 0.4 5.5e-06 25.8 0.1 6.2 7 0 0 7 7 7 2 EF-hand domain EF-hand_7 PF13499.1 KEZ39031.1 - 2.9e-14 52.9 2.4 1.5e-06 28.2 0.2 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 KEZ39031.1 - 4.2e-12 44.8 1.0 2e-05 23.7 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KEZ39031.1 - 1.3e-10 40.6 5.2 0.0034 16.9 0.0 5.5 5 1 1 6 6 6 3 EF-hand domain pair EF-hand_9 PF14658.1 KEZ39031.1 - 0.0025 17.6 0.0 4.5 7.2 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain Cyclin_N PF00134.18 KEZ39032.1 - 9e-41 138.4 0.1 1.5e-40 137.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEZ39032.1 - 1.1e-31 109.1 0.0 2.6e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 KEZ39033.1 - 0.00064 19.5 12.3 0.0011 18.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KEZ39033.1 - 0.013 14.6 0.1 0.013 14.6 0.0 2.6 3 0 0 3 3 3 0 Histone chaperone domain CHZ MFS_1 PF07690.11 KEZ39034.1 - 2.8e-32 111.8 45.0 2.8e-32 111.8 31.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ39034.1 - 0.014 15.1 14.4 0.15 11.8 2.6 3.9 4 0 0 4 4 4 0 MFS_1 like family ESSS PF10183.4 KEZ39034.1 - 0.079 13.3 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_M50 PF02163.17 KEZ39034.1 - 0.12 11.3 1.6 0.39 9.6 1.1 1.9 1 0 0 1 1 1 0 Peptidase family M50 Abhydrolase_6 PF12697.2 KEZ39035.1 - 3.6e-07 30.2 1.6 9e-07 28.9 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ39035.1 - 1.7e-05 24.5 1.3 0.00049 19.7 0.9 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ39035.1 - 4.6e-05 23.1 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 KEZ39035.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 KEZ39035.1 - 0.032 13.7 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF3089 PF11288.3 KEZ39035.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 KEZ39035.1 - 0.045 13.3 0.0 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.15 KEZ39035.1 - 0.047 13.9 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DUF2305 PF10230.4 KEZ39035.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2974 PF11187.3 KEZ39035.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HpcH_HpaI PF03328.9 KEZ39036.1 - 0.0053 15.6 0.0 0.006 15.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Adeno_E3B PF03376.9 KEZ39037.1 - 0.45 10.4 7.6 0.22 11.4 1.0 2.8 2 0 0 2 2 2 0 Adenovirus E3B protein RNA_pol_Rpc4 PF05132.9 KEZ39038.1 - 2.9e-12 46.6 0.0 2.9e-12 46.6 0.0 3.4 4 1 0 4 4 4 1 RNA polymerase III RPC4 STAG PF08514.6 KEZ39039.1 - 1.8e-27 95.3 0.8 5.8e-27 93.7 0.5 1.9 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KEZ39039.1 - 5.4e-05 23.3 0.0 0.079 13.2 0.0 3.6 2 1 0 2 2 2 1 HEAT repeats DUF422 PF04240.7 KEZ39039.1 - 0.005 16.2 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF422) Cnd1 PF12717.2 KEZ39039.1 - 0.03 14.1 0.1 0.14 12.0 0.0 2.2 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Baculo_PEP_C PF04513.7 KEZ39039.1 - 0.13 12.1 3.2 1 9.1 0.0 3.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SURF2 PF05477.6 KEZ39039.1 - 6.5 5.7 26.2 0.026 13.6 2.4 3.3 2 1 2 4 4 4 0 Surfeit locus protein 2 (SURF2) POT1 PF02765.12 KEZ39040.1 - 2e-06 27.7 0.0 4.8e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 UPF0172 PF03665.8 KEZ39040.1 - 0.057 12.8 0.4 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Arm PF00514.18 KEZ39041.1 - 9.1e-96 310.8 15.0 3.6e-14 51.9 0.2 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEZ39041.1 - 3.9e-26 91.1 0.5 2.6e-10 40.4 0.0 5.8 1 1 3 5 5 5 5 HEAT repeats IBB PF01749.15 KEZ39041.1 - 6.8e-24 83.8 1.3 1.1e-23 83.1 0.9 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KEZ39041.1 - 7.5e-23 80.3 11.9 1e-09 38.5 0.0 6.1 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 KEZ39041.1 - 4.4e-21 73.0 2.3 1.1e-06 28.1 0.0 7.2 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.8 KEZ39041.1 - 1.4e-10 40.7 0.0 0.017 14.2 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 KEZ39041.1 - 2.6e-05 22.7 0.0 0.0024 16.2 0.0 2.5 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 KEZ39041.1 - 0.0001 22.1 0.0 1.1 9.1 0.0 4.4 2 1 4 6 6 6 1 V-ATPase subunit H HEAT_PBS PF03130.11 KEZ39041.1 - 0.00048 20.3 0.3 1.4 9.5 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 KEZ39041.1 - 0.0023 16.2 0.1 0.3 9.3 0.0 2.9 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 KEZ39041.1 - 0.017 14.7 0.0 18 5.0 0.0 3.6 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NAD_kinase PF01513.16 KEZ39042.1 - 2.4e-65 220.1 0.0 3.7e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase HIT PF01230.18 KEZ39043.1 - 3.4e-16 59.5 0.9 8.1e-16 58.3 0.7 1.6 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEZ39043.1 - 6.1e-15 55.4 4.8 1.8e-13 50.7 3.3 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.20 KEZ39044.1 - 4.5e-31 107.9 0.0 6.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39044.1 - 2.5e-11 43.1 0.0 4.1e-10 39.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PfkB PF00294.19 KEZ39045.1 - 6e-19 68.2 0.0 1.2e-16 60.7 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CoA_transf_3 PF02515.12 KEZ39045.1 - 0.073 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 CoA-transferase family III pRN1_helical PF13010.1 KEZ39046.1 - 0.018 14.7 0.5 0.018 14.7 0.4 2.0 2 0 0 2 2 2 0 Primase helical domain CytochromB561_N PF09786.4 KEZ39046.1 - 0.33 9.3 18.8 0.45 8.8 13.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal SDH_alpha PF03313.10 KEZ39046.1 - 2.7 6.9 8.2 13 4.7 4.1 2.2 2 0 0 2 2 2 0 Serine dehydratase alpha chain Las1 PF04031.8 KEZ39047.1 - 3.8e-60 202.0 0.1 5.8e-60 201.4 0.1 1.3 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 KEZ39047.1 - 4.5e-23 81.9 3.6 9.8e-23 80.8 2.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEZ39047.1 - 3.7e-05 23.3 0.1 8.2e-05 22.2 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.20 KEZ39048.1 - 6.6e-05 22.1 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KEZ39048.1 - 0.00034 20.0 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KEZ39048.1 - 0.039 13.6 0.2 0.18 11.5 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family IF4E PF01652.13 KEZ39050.1 - 1e-37 129.2 0.2 1.3e-37 128.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HA2 PF04408.18 KEZ39051.1 - 2.8e-18 65.7 0.6 8.4e-18 64.2 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEZ39051.1 - 1.1e-14 54.0 0.0 2.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KEZ39051.1 - 1.2e-14 54.0 0.0 2.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 KEZ39051.1 - 1.8e-10 40.6 0.2 3.5e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 KEZ39051.1 - 3.6e-09 36.3 0.3 1.2e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEZ39051.1 - 0.00039 20.5 0.1 0.0011 19.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 KEZ39051.1 - 0.0034 17.6 0.6 0.012 15.9 0.4 2.0 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 KEZ39051.1 - 0.004 16.6 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 KEZ39051.1 - 0.0092 15.1 0.4 0.024 13.7 0.3 1.7 1 1 0 1 1 1 1 KaiC T2SE PF00437.15 KEZ39051.1 - 0.02 13.7 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 KEZ39051.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 KEZ39051.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 KEZ39051.1 - 0.11 12.8 0.2 0.11 12.8 0.1 2.0 2 0 0 2 2 1 0 AAA domain Zn_clus PF00172.13 KEZ39052.1 - 3.5e-08 33.2 14.2 6.8e-08 32.2 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEZ39052.1 - 0.00067 18.3 0.3 0.00096 17.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rhomboid PF01694.17 KEZ39053.1 - 1.1e-39 135.7 8.6 2.3e-39 134.7 6.0 1.5 1 0 0 1 1 1 1 Rhomboid family DNA_pol_B PF00136.16 KEZ39054.1 - 7.1e-145 483.3 2.6 1.1e-144 482.7 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEZ39054.1 - 1.3e-83 280.5 1.0 2.5e-83 279.6 0.1 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KEZ39054.1 - 2.5e-23 81.8 5.1 5e-23 80.8 3.6 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KEZ39054.1 - 0.00044 20.1 0.1 0.0017 18.1 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KEZ39054.1 - 0.0021 17.6 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 KEZ39054.1 - 0.0067 15.1 1.3 0.05 12.2 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DUF2614 PF11023.3 KEZ39054.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) GTP_EFTU PF00009.22 KEZ39055.1 - 2.8e-59 199.7 0.2 3.7e-59 199.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEZ39055.1 - 3e-25 88.2 0.0 7.2e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEZ39055.1 - 1.3e-15 57.2 2.9 3.2e-15 55.9 2.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEZ39055.1 - 1.5e-05 24.9 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KEZ39055.1 - 2.5e-05 23.8 0.5 6.7e-05 22.4 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 KEZ39055.1 - 0.0059 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KEZ39055.1 - 0.032 13.3 0.1 0.1 11.7 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KEZ39055.1 - 0.033 13.6 0.2 12 5.4 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2823 PF11034.3 KEZ39056.1 - 1.1e-30 105.5 3.9 1.4e-30 105.2 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) RNA_pol_I_A49 PF06870.7 KEZ39056.1 - 0.19 10.2 1.1 0.2 10.1 0.8 1.0 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor EBP PF05241.7 KEZ39057.1 - 7.5e-65 217.5 10.4 9e-65 217.3 7.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein PsbN PF02468.10 KEZ39057.1 - 0.94 9.1 3.5 0.88 9.2 0.6 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) DUF788 PF05620.6 KEZ39057.1 - 1.9 8.3 6.9 0.75 9.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Romo1 PF10247.4 KEZ39058.1 - 0.027 14.6 0.7 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 PAP2 PF01569.16 KEZ39059.1 - 2.5e-14 53.0 6.1 3.8e-14 52.4 4.2 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KEZ39059.1 - 0.0046 16.7 0.3 0.24 11.1 0.0 2.5 2 1 0 2 2 2 2 Divergent PAP2 family IBR PF01485.16 KEZ39060.1 - 5.7e-18 64.5 38.2 8.3e-13 48.0 4.3 3.8 3 1 1 4 4 4 3 IBR domain RWD PF05773.17 KEZ39060.1 - 5.3e-17 61.7 0.0 1.2e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KEZ39060.1 - 2.4e-05 24.0 8.0 2.4e-05 24.0 5.6 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KEZ39060.1 - 0.0031 17.1 6.0 0.0031 17.1 4.1 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEZ39060.1 - 0.017 14.9 0.7 0.017 14.9 0.5 4.1 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING NDT80_PhoG PF05224.7 KEZ39061.1 - 8e-35 120.5 1.7 2.9e-34 118.6 0.0 2.4 3 0 0 3 3 3 1 NDT80 / PhoG like DNA-binding family DUF3402 PF11882.3 KEZ39062.1 - 1.6e-156 521.4 0.0 2.4e-156 520.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KEZ39062.1 - 1.5e-74 250.4 0.0 2.7e-74 249.6 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein MARVEL PF01284.18 KEZ39063.1 - 0.00039 20.2 11.7 0.0047 16.7 8.9 1.9 1 1 1 2 2 2 1 Membrane-associating domain 7tm_7 PF08395.7 KEZ39063.1 - 0.15 11.0 1.2 0.41 9.5 0.2 1.8 2 0 0 2 2 2 0 7tm Chemosensory receptor Antimicrobial10 PF08105.6 KEZ39063.1 - 5.5 6.7 8.5 4.5 6.9 2.0 2.8 1 1 1 2 2 2 0 Metchnikowin family WSC PF01822.14 KEZ39064.1 - 1e-40 137.5 59.5 7.9e-20 70.5 5.4 6.2 4 2 1 5 5 5 3 WSC domain peroxidase PF00141.18 KEZ39064.1 - 2e-20 73.2 0.0 4.7e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Peroxidase DUF605 PF04652.11 KEZ39064.1 - 0.00017 21.1 34.1 0.00033 20.1 23.7 1.5 1 0 0 1 1 1 1 Vta1 like HSBP1 PF06825.7 KEZ39065.1 - 6.1e-17 60.9 0.1 7.1e-17 60.7 0.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 KEZ39065.1 - 0.0042 16.4 0.2 0.46 9.8 0.1 2.1 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin HR1 PF02185.11 KEZ39065.1 - 0.012 15.3 2.8 0.034 13.8 0.4 1.9 1 1 1 2 2 2 0 Hr1 repeat Apolipoprotein PF01442.13 KEZ39065.1 - 0.013 14.9 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain WEMBL PF05701.6 KEZ39065.1 - 0.015 13.7 0.6 0.016 13.7 0.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light WXG100 PF06013.7 KEZ39065.1 - 0.041 13.8 0.2 0.1 12.5 0.2 1.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.17 KEZ39065.1 - 0.048 13.6 1.5 0.35 10.9 1.0 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 KEZ39065.1 - 0.068 12.9 0.1 0.082 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UBN2 PF14223.1 KEZ39065.1 - 0.069 12.9 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Baculo_PEP_C PF04513.7 KEZ39065.1 - 0.1 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 KEZ39065.1 - 0.12 12.2 0.7 1.4 8.7 0.0 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Reo_sigmaC PF04582.7 KEZ39065.1 - 0.13 11.4 2.0 0.14 11.3 1.4 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DELLA PF12041.3 KEZ39065.1 - 0.22 11.2 2.8 1.6 8.4 0.2 2.0 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal Thioredoxin PF00085.15 KEZ39066.1 - 2.1e-61 204.0 0.2 7.3e-31 105.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KEZ39066.1 - 1.8e-24 86.1 6.5 3.9e-24 85.0 4.5 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KEZ39066.1 - 4.2e-19 68.7 3.4 3.3e-08 33.6 0.0 3.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEZ39066.1 - 6.6e-14 51.7 0.2 1.9e-05 24.7 0.0 4.2 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KEZ39066.1 - 2.6e-11 43.3 0.1 0.00026 20.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 KEZ39066.1 - 2.3e-07 30.8 0.0 0.0099 15.6 0.0 2.9 2 1 1 3 3 3 3 Thioredoxin-like domain AhpC-TSA PF00578.16 KEZ39066.1 - 1.8e-06 27.6 1.7 0.038 13.6 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.1 KEZ39066.1 - 0.00013 21.5 1.6 0.11 12.0 0.0 3.2 3 1 1 4 4 4 2 Thioredoxin Glutaredoxin PF00462.19 KEZ39066.1 - 0.00044 20.1 0.8 1.6 8.7 0.0 3.5 3 1 0 3 3 3 2 Glutaredoxin Redoxin PF08534.5 KEZ39066.1 - 0.00073 19.0 1.2 0.17 11.4 0.1 2.6 2 1 1 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 KEZ39066.1 - 0.001 18.8 0.0 0.1 12.4 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 KEZ39066.1 - 0.013 15.5 7.3 1.3 9.0 0.0 3.9 3 1 1 4 4 4 0 Thioredoxin DDE_Tnp_1_2 PF13586.1 KEZ39066.1 - 0.09 12.9 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain ELFV_dehydrog PF00208.16 KEZ39067.1 - 6.1e-83 278.1 1.2 7.6e-83 277.8 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KEZ39067.1 - 9.7e-48 161.0 0.0 2.2e-47 159.9 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KEZ39067.1 - 0.023 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GMC_oxred_N PF00732.14 KEZ39068.1 - 1.1e-10 41.1 0.0 5.7e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39068.1 - 2.7e-08 34.1 0.1 1.1e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KEZ39068.1 - 0.0046 16.9 0.4 0.019 14.9 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ39068.1 - 0.048 12.5 0.9 0.095 11.5 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF900 PF05990.7 KEZ39068.1 - 0.21 10.9 0.0 0.45 9.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pyr_redox_2 PF07992.9 KEZ39068.1 - 0.37 10.6 2.0 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Suc_Fer-like PF06999.7 KEZ39069.1 - 7.5e-38 130.8 0.0 1e-37 130.3 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Tannase PF07519.6 KEZ39070.1 - 3.6e-85 286.4 0.0 4.6e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEZ39070.1 - 7e-05 22.8 0.1 0.00027 20.9 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ39070.1 - 0.0002 20.9 0.1 0.00094 18.7 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ39070.1 - 0.043 13.0 0.0 4.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ39070.1 - 0.044 13.5 0.1 0.77 9.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Aa_trans PF01490.13 KEZ39071.1 - 1.9e-81 273.6 30.1 2.4e-81 273.3 20.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein KAT11 PF08214.6 KEZ39072.1 - 3.6e-89 299.2 0.0 5.1e-89 298.7 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein 2-Hacid_dh_C PF02826.14 KEZ39072.1 - 8.9e-36 122.6 0.0 1.4e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribonucleas_3_3 PF14622.1 KEZ39072.1 - 2.4e-25 88.9 0.0 4.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like 2-Hacid_dh PF00389.25 KEZ39072.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEZ39072.1 - 2.1e-05 24.4 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEZ39072.1 - 0.0037 17.6 0.0 0.0098 16.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KEZ39072.1 - 0.063 13.5 0.0 0.62 10.3 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF1788 PF08747.6 KEZ39073.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) zf-RING_2 PF13639.1 KEZ39074.1 - 5.1e-09 35.8 5.4 6.2e-08 32.3 1.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KEZ39074.1 - 2.5e-06 27.4 4.0 1.1e-05 25.4 1.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEZ39074.1 - 1.2e-05 24.8 2.0 0.00021 20.9 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ39074.1 - 1.4e-05 24.7 3.8 2.5e-05 23.8 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEZ39074.1 - 8.3e-05 22.5 6.2 0.0003 20.7 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ39074.1 - 0.00041 19.9 3.1 0.0014 18.2 0.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEZ39074.1 - 0.0015 18.3 1.1 0.0015 18.3 0.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KEZ39074.1 - 0.033 13.9 2.5 0.049 13.4 0.2 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Rtf2 PF04641.7 KEZ39074.1 - 0.04 13.1 0.2 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger Prok-RING_4 PF14447.1 KEZ39074.1 - 0.19 11.3 3.7 1.2 8.7 0.4 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-H2C2_2 PF13465.1 KEZ39074.1 - 0.19 12.0 0.9 31 5.1 0.1 2.8 2 1 0 2 2 2 0 Zinc-finger double domain FANCL_C PF11793.3 KEZ39074.1 - 1.9 8.5 10.8 0.88 9.5 1.2 3.0 2 1 1 3 3 3 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KEZ39074.1 - 3.9 7.1 7.0 1.7 8.2 1.8 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain OppC_N PF12911.2 KEZ39074.1 - 4.3 6.7 5.3 8.6 5.8 3.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C zf-C3HC4_4 PF15227.1 KEZ39074.1 - 4.4 7.2 7.2 0.82 9.5 0.7 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KEZ39074.1 - 5.1 6.8 8.0 0.62 9.8 2.2 2.1 2 1 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.1 KEZ39074.1 - 5.8 6.7 6.3 1.6 8.5 0.5 2.8 2 1 1 3 3 3 0 RING-type zinc-finger E1-E2_ATPase PF00122.15 KEZ39075.1 - 3.2e-62 209.5 5.4 6.5e-62 208.5 3.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ39075.1 - 8.5e-37 126.4 4.4 8.5e-37 126.4 3.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ39075.1 - 2.5e-31 109.7 0.0 4.5e-30 105.6 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ39075.1 - 2e-18 65.5 1.1 7.9e-18 63.6 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEZ39075.1 - 5.2e-18 64.7 0.0 1.2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ39075.1 - 7e-15 55.6 0.0 1.6e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ39075.1 - 0.00029 20.5 0.2 0.0029 17.2 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase KR PF08659.5 KEZ39075.1 - 0.026 14.2 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 KR domain DUF2207 PF09972.4 KEZ39075.1 - 1.2 7.6 2.7 1.7 7.1 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) IPP-2 PF04979.9 KEZ39076.1 - 1.3e-12 48.1 5.4 3.7e-06 27.2 0.1 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF2946 PF11162.3 KEZ39077.1 - 0.022 14.9 3.5 0.027 14.6 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF2076 PF09849.4 KEZ39077.1 - 0.072 13.1 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TerY-C PF15616.1 KEZ39077.1 - 0.073 12.9 1.9 0.12 12.3 1.3 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain DUF2933 PF11666.3 KEZ39077.1 - 2 8.0 9.1 3.7 7.1 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Ribosomal_L27 PF01016.14 KEZ39078.1 - 4.5e-22 77.6 0.0 4.5e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L27 protein Metal_resist PF13801.1 KEZ39078.1 - 0.45 10.4 5.2 1 9.3 3.6 1.5 1 0 0 1 1 1 0 Heavy-metal resistance DUF3716 PF12511.3 KEZ39079.1 - 0.00011 21.6 2.9 0.00025 20.6 2.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-H2C2_2 PF13465.1 KEZ39079.1 - 1.1 9.7 6.1 0.3 11.4 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double domain CorA PF01544.13 KEZ39081.1 - 1.9e-11 43.5 2.7 3.4e-11 42.7 0.6 2.0 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 KEZ39081.1 - 1.6e-06 27.6 0.0 2.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEZ39081.1 - 0.0037 17.1 1.8 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KEZ39081.1 - 0.04 13.3 0.0 0.14 11.5 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase TAFII28 PF04719.9 KEZ39082.1 - 1e-16 60.4 0.0 6.2e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 hTAFII28-like protein conserved region Vfa1 PF08432.5 KEZ39082.1 - 0.22 11.5 2.5 0.37 10.7 1.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GTP_cyclohydroI PF01227.17 KEZ39083.1 - 6e-71 237.4 0.1 1.2e-70 236.4 0.1 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KEZ39083.1 - 0.00043 20.1 0.0 0.0008 19.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein IER PF05760.7 KEZ39083.1 - 0.15 11.9 5.2 0.23 11.3 3.6 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) CDK5_activator PF03261.10 KEZ39083.1 - 0.27 10.5 2.2 0.39 10.0 1.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4661 PF15576.1 KEZ39083.1 - 1.9 8.0 5.5 2.6 7.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF4407 PF14362.1 KEZ39083.1 - 2.8 6.8 7.4 4.1 6.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dicty_REP PF05086.7 KEZ39083.1 - 5.3 4.6 10.1 6.9 4.2 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_76 PF03663.9 KEZ39084.1 - 4.7e-147 490.2 4.7 5.8e-147 489.9 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEZ39084.1 - 0.28 10.1 5.5 1.6 7.6 0.2 2.7 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Exo_endo_phos PF03372.18 KEZ39085.1 - 7.5e-27 94.8 0.7 1.7e-26 93.6 0.1 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 KEZ39085.1 - 0.013 15.2 0.0 0.044 13.5 0.0 1.9 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 KEZ39085.1 - 0.026 14.3 0.3 3.4 7.7 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat MRF_C1 PF13887.1 KEZ39085.1 - 0.2 10.7 0.0 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 SRR1 PF07985.7 KEZ39087.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 SRR1 NACHT PF05729.7 KEZ39088.1 - 3.4e-10 39.8 0.1 6.9e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ39088.1 - 3e-05 24.1 0.0 0.00023 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEZ39088.1 - 0.017 15.3 0.5 0.073 13.3 0.0 2.3 3 0 0 3 3 3 0 ABC transporter Dynactin PF12455.3 KEZ39088.1 - 0.026 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Dynein associated protein AAA_30 PF13604.1 KEZ39088.1 - 0.037 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ39088.1 - 0.038 13.5 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KEZ39088.1 - 0.22 11.7 0.1 0.53 10.4 0.1 1.7 1 0 0 1 1 1 0 RNA helicase Herpes_Helicase PF02689.9 KEZ39088.1 - 0.31 8.7 0.0 0.57 7.8 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF3818 PF12825.2 KEZ39089.1 - 1.4e-31 109.4 0.0 2.6e-22 78.9 0.0 2.9 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KEZ39089.1 - 2.2e-31 108.2 0.0 3.8e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 PX-associated Phage_RpbA PF10789.4 KEZ39089.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA M16C_assoc PF08367.6 KEZ39090.1 - 1.5e-62 210.6 0.0 2.1e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KEZ39090.1 - 2.1e-32 112.3 0.0 5.6e-18 65.2 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEZ39090.1 - 5.2e-07 29.5 0.0 2.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) tRNA_Me_trans PF03054.11 KEZ39090.1 - 0.23 9.9 0.0 0.37 9.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Taxilin PF09728.4 KEZ39091.1 - 1.7e-83 280.3 42.7 2.9e-83 279.4 29.6 1.4 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF904 PF06005.7 KEZ39091.1 - 0.0027 17.9 2.8 0.0027 17.9 1.9 5.6 2 2 2 4 4 4 2 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 KEZ39091.1 - 0.0035 17.0 40.8 0.0079 15.9 4.7 4.6 3 1 1 4 4 4 3 TATA element modulatory factor 1 TATA binding Sec20 PF03908.8 KEZ39091.1 - 3.1 7.5 11.0 1.4 8.6 0.3 3.8 3 1 1 4 4 4 0 Sec20 Nucleoplasmin PF03066.10 KEZ39091.1 - 8.6 5.8 19.8 1.4 8.4 10.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin Orn_Arg_deC_N PF02784.11 KEZ39092.1 - 4.4e-76 255.4 0.0 6.2e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KEZ39092.1 - 1.4e-29 102.1 0.1 2.6e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain WD40 PF00400.27 KEZ39093.1 - 5.5e-119 384.2 50.2 1.6e-12 46.8 0.1 12.5 12 0 0 12 12 12 12 WD domain, G-beta repeat NACHT PF05729.7 KEZ39093.1 - 1.2e-15 57.6 0.0 2.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 KEZ39093.1 - 3.5e-10 38.6 17.7 0.013 13.6 0.1 7.0 2 2 3 6 6 6 5 Nucleoporin Nup120/160 Nbas_N PF15492.1 KEZ39093.1 - 0.00015 20.9 16.4 1.2 8.1 0.1 8.2 5 3 3 9 9 9 2 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.1 KEZ39093.1 - 0.002 18.1 0.0 0.009 16.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 KEZ39093.1 - 0.012 15.7 0.0 0.045 13.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KEZ39093.1 - 0.036 13.7 0.1 0.17 11.5 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase DUF745 PF05335.8 KEZ39093.1 - 0.18 11.3 4.1 0.48 9.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Peptidase_M16_C PF05193.16 KEZ39094.1 - 3.7e-22 78.8 0.0 3.3e-16 59.5 0.0 4.0 3 1 0 4 4 4 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEZ39094.1 - 1.4e-06 28.1 0.0 5.3e-06 26.2 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 KEZ39094.1 - 0.007 15.2 5.1 0.52 9.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16C associated CTD_bind PF04818.8 KEZ39095.1 - 4.8e-09 36.3 0.0 1.6e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. KAR9 PF08580.5 KEZ39095.1 - 2.1 6.5 13.8 2.7 6.1 9.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF936 PF06075.7 KEZ39095.1 - 4.7 6.0 15.5 6.1 5.6 10.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) B56 PF01603.15 KEZ39096.1 - 2.5e-174 579.6 8.4 3e-174 579.4 5.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 KEZ39096.1 - 0.029 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Dynamin family FAM220 PF15487.1 KEZ39096.1 - 1 8.6 7.6 1.9 7.8 5.2 1.3 1 0 0 1 1 1 0 FAM220 family Tau95 PF09734.4 KEZ39097.1 - 3.5e-59 200.6 0.0 4.9e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit zf-C2H2 PF00096.21 KEZ39098.1 - 6.2e-13 48.2 21.4 0.092 13.1 0.2 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ39098.1 - 3.1e-08 33.3 17.6 0.33 11.3 0.7 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ39098.1 - 0.001 19.1 11.1 1.1 9.4 0.1 4.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KEZ39098.1 - 0.0041 16.7 3.5 6 6.6 0.1 3.6 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 KEZ39098.1 - 0.012 15.8 17.0 4.6 7.7 0.1 5.2 5 0 0 5 5 5 0 Zinc-finger double domain zinc_ribbon_4 PF13717.1 KEZ39098.1 - 0.022 14.4 4.0 1.8 8.2 0.0 3.9 3 0 0 3 3 3 0 zinc-ribbon domain DUF4503 PF14951.1 KEZ39098.1 - 0.078 11.1 0.4 0.12 10.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) zf-C2H2_6 PF13912.1 KEZ39098.1 - 0.14 12.1 24.9 0.3 11.0 0.1 5.3 6 0 0 6 6 6 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 KEZ39098.1 - 0.52 9.9 8.2 1.7 8.2 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Tmemb_55A PF09788.4 KEZ39098.1 - 2 7.4 4.7 0.28 10.2 0.1 1.8 2 0 0 2 2 2 0 Transmembrane protein 55A zf-DHHC PF01529.15 KEZ39099.1 - 6.2e-42 142.9 5.8 6.2e-42 142.9 4.0 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase LRS4 PF10422.4 KEZ39099.1 - 0.041 13.2 0.5 0.078 12.3 0.0 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 DZR PF12773.2 KEZ39099.1 - 0.13 12.0 6.1 0.24 11.2 4.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zw10 PF06248.8 KEZ39100.1 - 9.7e-16 57.0 4.6 2.4e-13 49.1 0.6 2.1 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Leu_zip PF15294.1 KEZ39100.1 - 0.047 12.8 7.8 0.18 10.8 0.1 3.4 3 1 0 3 3 3 0 Leucine zipper DUF733 PF05306.6 KEZ39100.1 - 0.3 11.4 2.2 0.3 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF733) Peptidase_M48 PF01435.13 KEZ39101.1 - 2.1e-49 168.1 0.1 3e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KEZ39101.1 - 0.029 13.3 0.4 0.065 12.1 0.3 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.4 KEZ39101.1 - 0.16 11.6 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 SprT-like family SNF2_N PF00176.18 KEZ39102.1 - 1.6e-39 135.5 0.0 2.5e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ39102.1 - 4e-07 29.8 0.0 8.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ39102.1 - 2.9e-06 27.2 0.0 1.1e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 KEZ39102.1 - 0.0093 15.6 4.3 0.019 14.6 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ39102.1 - 0.01 15.6 5.2 0.02 14.6 3.6 1.4 1 0 0 1 1 1 0 Ring finger domain Fer2_3 PF13085.1 KEZ39102.1 - 0.12 12.2 0.2 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2616 PF11077.3 KEZ39102.1 - 0.13 11.7 1.2 0.35 10.3 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-C3HC4_2 PF13923.1 KEZ39102.1 - 0.2 11.7 5.5 0.44 10.6 3.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ39102.1 - 2 8.1 5.9 4.3 7.0 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L38e PF01781.13 KEZ39103.1 - 6e-33 112.4 1.3 7e-33 112.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family GHMP_kinases_N PF00288.21 KEZ39104.1 - 1.4e-19 69.9 0.0 2.8e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KEZ39104.1 - 1.2e-08 35.0 0.0 2.7e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KEZ39104.1 - 0.009 15.2 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.17 KEZ39105.1 - 3.2e-37 124.3 16.6 2.4e-07 29.7 0.2 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_2 PF07719.12 KEZ39105.1 - 0.18 11.7 3.0 0.43 10.6 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ39105.1 - 0.33 11.7 8.0 2 9.2 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NTF2 PF02136.15 KEZ39106.1 - 0.0003 21.1 0.9 0.0025 18.1 0.6 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain E1-E2_ATPase PF00122.15 KEZ39107.1 - 3.1e-26 91.8 0.3 4.4e-26 91.3 0.2 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ39107.1 - 0.00043 19.8 0.7 0.00043 19.8 0.5 2.1 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus LHC PF00556.15 KEZ39107.1 - 0.1 12.4 0.7 0.48 10.3 0.5 2.3 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit MFS_1 PF07690.11 KEZ39108.1 - 5.8e-33 114.0 32.2 1e-24 86.9 6.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39108.1 - 5e-07 28.6 17.9 9.1e-07 27.8 1.5 3.8 3 1 1 4 4 4 2 Sugar (and other) transporter ATG22 PF11700.3 KEZ39108.1 - 6.3e-07 28.2 8.9 0.0018 16.8 0.1 2.4 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 KEZ39108.1 - 1.9e-06 26.5 1.4 1.9e-06 26.5 1.0 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein DUF2755 PF10954.3 KEZ39108.1 - 0.017 14.8 0.2 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) AAA_16 PF13191.1 KEZ39110.1 - 4.3e-09 36.6 0.1 6.5e-08 32.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEZ39110.1 - 5e-05 23.4 0.1 0.0011 19.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain TPR_19 PF14559.1 KEZ39110.1 - 7.3e-05 23.0 2.8 0.37 11.1 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.7 KEZ39110.1 - 0.00023 20.8 0.0 0.001 18.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KEZ39110.1 - 0.03 14.0 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain TPR_10 PF13374.1 KEZ39110.1 - 0.098 12.6 10.7 33 4.5 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2561 PF10812.3 KEZ39112.1 - 0.026 14.1 0.1 0.098 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Methyltransf_2 PF00891.13 KEZ39113.1 - 6.5e-26 90.9 0.0 3.7e-25 88.5 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 KEZ39113.1 - 0.0028 17.3 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 KEZ39113.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DUF4066 PF13278.1 KEZ39115.1 - 2.1e-12 46.6 0.0 4.1e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEZ39115.1 - 3.8e-05 23.1 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1996 PF09362.5 KEZ39116.1 - 2.7e-89 298.8 0.4 3.5e-89 298.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ferric_reduct PF01794.14 KEZ39117.1 - 1.4e-19 70.3 14.0 1.4e-19 70.3 9.7 2.3 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEZ39117.1 - 9.6e-08 31.8 0.0 0.0017 18.1 0.0 3.1 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.7 KEZ39117.1 - 4.6e-06 26.6 0.7 0.13 12.2 0.0 3.0 2 1 1 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KEZ39117.1 - 0.0091 16.5 0.1 0.083 13.4 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain AAA_12 PF13087.1 KEZ39118.1 - 8.2e-42 142.8 0.0 2.7e-41 141.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEZ39118.1 - 4.6e-40 136.8 1.6 3.9e-12 46.5 0.0 6.7 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KEZ39118.1 - 7.2e-33 114.1 13.2 2.6e-27 95.9 0.0 5.8 6 0 0 6 6 5 2 AAA domain AAA_19 PF13245.1 KEZ39118.1 - 4.8e-22 77.5 5.0 8.1e-10 38.3 0.1 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 KEZ39118.1 - 1e-14 54.7 5.5 0.0045 17.1 0.0 8.0 4 3 0 4 4 4 2 AAA domain AAA_30 PF13604.1 KEZ39118.1 - 1.6e-13 50.7 13.3 1.9e-06 27.6 0.0 6.5 6 1 0 6 6 5 3 AAA domain AAA_16 PF13191.1 KEZ39118.1 - 3.3e-10 40.2 10.1 0.037 14.0 0.0 6.2 6 0 0 6 6 6 3 AAA ATPase domain AAA_5 PF07728.9 KEZ39118.1 - 2.6e-09 36.9 6.1 0.078 12.7 0.0 5.1 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEZ39118.1 - 8e-09 36.3 18.3 0.23 12.2 0.0 6.6 6 0 0 6 6 5 4 AAA domain RuvB_N PF05496.7 KEZ39118.1 - 8.4e-09 34.8 0.4 0.021 13.8 0.0 5.3 5 2 0 5 5 5 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KEZ39118.1 - 3e-08 33.1 0.4 0.064 12.4 0.0 4.7 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEZ39118.1 - 5.8e-08 32.3 0.1 0.35 10.2 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KEZ39118.1 - 1.8e-06 28.0 1.5 3.7 7.7 0.0 5.5 5 1 0 5 5 4 1 RNA helicase AAA_33 PF13671.1 KEZ39118.1 - 2.1e-06 27.6 6.8 0.53 10.1 0.0 5.3 4 0 0 4 4 4 2 AAA domain KaiC PF06745.8 KEZ39118.1 - 1.5e-05 24.2 4.7 0.0045 16.1 0.0 4.4 5 0 0 5 5 5 1 KaiC Torsin PF06309.6 KEZ39118.1 - 1.9e-05 24.5 0.0 4 7.3 0.0 4.7 4 0 0 4 4 4 1 Torsin PhoH PF02562.11 KEZ39118.1 - 6e-05 22.3 0.3 1.7 7.8 0.0 4.6 4 0 0 4 4 4 1 PhoH-like protein AAA_10 PF12846.2 KEZ39118.1 - 0.00013 21.4 10.7 15 4.8 0.2 7.2 6 2 0 7 7 7 0 AAA-like domain AAA_24 PF13479.1 KEZ39118.1 - 0.00054 19.5 10.5 1.3 8.5 0.0 5.3 6 0 0 6 6 5 1 AAA domain AAA_25 PF13481.1 KEZ39118.1 - 0.0017 17.7 4.5 32 3.8 0.0 5.7 4 1 1 5 5 5 0 AAA domain Helicase_RecD PF05127.9 KEZ39118.1 - 0.0018 17.9 0.3 0.37 10.4 0.0 3.4 3 0 0 3 3 2 1 Helicase Guanylate_cyc_2 PF09778.4 KEZ39118.1 - 0.0028 16.8 0.0 0.22 10.7 0.0 2.9 3 0 0 3 3 3 1 Guanylylate cyclase AAA_18 PF13238.1 KEZ39118.1 - 0.0083 16.4 25.1 2.4 8.4 0.0 6.5 7 0 0 7 7 5 3 AAA domain MobB PF03205.9 KEZ39118.1 - 0.012 15.3 2.2 45 3.7 0.0 4.8 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KEZ39118.1 - 0.02 14.8 13.6 2.5 8.0 0.1 5.4 5 0 0 5 5 5 0 AAA domain DUF2075 PF09848.4 KEZ39118.1 - 0.028 13.4 0.0 0.028 13.4 0.0 6.6 8 0 0 8 8 8 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 KEZ39118.1 - 0.15 11.5 2.9 1.3 8.4 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AMP-binding PF00501.23 KEZ39119.1 - 0 1067.5 0.0 8.2e-86 287.9 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 KEZ39119.1 - 4.8e-164 544.4 0.0 1.8e-53 181.3 0.0 4.9 4 2 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KEZ39119.1 - 3.4e-56 187.3 0.0 1.2e-13 51.1 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEZ39119.1 - 1e-31 109.6 1.1 1.4e-09 38.7 0.0 5.0 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 KEZ39119.1 - 1.1e-20 73.7 0.2 1.3e-19 70.2 0.1 3.0 3 0 0 3 3 3 1 HxxPF-repeated domain Collagen PF01391.13 KEZ39119.1 - 1.1 8.8 9.7 0.58 9.7 0.7 3.4 3 0 0 3 3 3 0 Collagen triple helix repeat (20 copies) DUF2884 PF11101.3 KEZ39119.1 - 1.7 7.9 0.6 1.1e+02 2.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) MFS_1 PF07690.11 KEZ39120.1 - 2.6e-40 138.2 18.5 2.6e-40 138.2 12.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.1 KEZ39120.1 - 0.061 13.3 0.2 0.061 13.3 0.1 2.8 2 1 0 2 2 2 0 Stage V sporulation protein AB Fungal_trans PF04082.13 KEZ39121.1 - 1.1e-39 135.9 0.6 1.5e-39 135.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NMT1 PF09084.6 KEZ39122.1 - 0.0047 16.5 0.0 1.4 8.4 0.0 2.5 2 1 0 2 2 2 2 NMT1/THI5 like p450 PF00067.17 KEZ39123.1 - 8.3e-35 120.1 0.0 1.1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2312 PF10073.4 KEZ39123.1 - 0.037 13.3 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF1761 PF08570.5 KEZ39125.1 - 0.053 13.5 4.9 0.85 9.6 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) GMC_oxred_N PF00732.14 KEZ39126.1 - 3.1e-46 157.8 0.0 4e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39126.1 - 2.5e-28 99.1 0.0 4.3e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KEZ39126.1 - 0.0048 15.8 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KEZ39126.1 - 0.031 13.1 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KEZ39126.1 - 0.046 12.3 0.2 0.08 11.5 0.0 1.4 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KEZ39126.1 - 0.047 12.5 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 KEZ39126.1 - 0.075 13.0 0.1 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Exo_endo_phos PF03372.18 KEZ39127.1 - 2.7e-05 24.2 1.5 3.9e-05 23.7 1.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family His_Phos_2 PF00328.17 KEZ39128.1 - 2.9e-30 105.7 0.0 4.2e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_hydro_16 PF00722.16 KEZ39129.1 - 1.7e-07 30.6 0.1 2.5e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.6 KEZ39129.1 - 0.00067 19.5 0.1 0.00096 19.0 0.1 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Pyrophosphatase PF00719.14 KEZ39130.1 - 1.8e-42 144.4 0.0 2.4e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF1996 PF09362.5 KEZ39131.1 - 1e-87 293.6 0.8 1.3e-87 293.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Phytase-like PF13449.1 KEZ39132.1 - 1.3e-26 93.7 0.0 3.4e-26 92.3 0.0 1.7 2 1 0 2 2 2 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 KEZ39132.1 - 0.1 11.4 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 SdiA-regulated FAD_binding_3 PF01494.14 KEZ39133.1 - 1e-27 97.1 0.1 4.2e-27 95.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ39133.1 - 9.4e-07 28.0 0.8 1.8e-05 23.8 0.3 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ39133.1 - 2.6e-06 27.6 0.0 4.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ39133.1 - 0.00014 21.7 0.2 0.00038 20.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEZ39133.1 - 0.00018 20.7 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KEZ39133.1 - 0.0016 17.4 1.1 0.015 14.2 0.1 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein ThiF PF00899.16 KEZ39133.1 - 0.0025 17.6 0.4 0.0053 16.5 0.3 1.5 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.19 KEZ39133.1 - 0.0042 15.9 0.0 0.0098 14.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 KEZ39133.1 - 0.0046 17.0 0.4 0.0095 16.0 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KEZ39133.1 - 0.0049 17.2 2.2 0.025 14.9 0.8 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ39133.1 - 0.0071 16.1 0.2 0.15 11.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 KEZ39133.1 - 0.0094 15.0 0.2 0.016 14.2 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KEZ39133.1 - 0.012 14.0 0.1 0.044 12.2 0.1 1.9 1 1 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KEZ39133.1 - 0.012 14.2 0.6 0.43 9.1 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 KEZ39133.1 - 0.026 14.5 0.1 0.07 13.1 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 KEZ39133.1 - 0.04 13.7 0.1 0.064 13.1 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.5 KEZ39133.1 - 0.057 13.0 0.5 0.12 12.0 0.2 1.6 2 0 0 2 2 2 0 KR domain ApbA PF02558.11 KEZ39133.1 - 0.097 12.1 0.9 0.17 11.2 0.6 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 KEZ39133.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KEZ39133.1 - 0.17 10.6 0.3 0.78 8.5 0.2 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A Transferase PF02458.10 KEZ39134.1 - 8.8e-11 40.8 0.0 7e-10 37.9 0.0 2.0 1 1 0 1 1 1 1 Transferase family Crystall PF00030.14 KEZ39135.1 - 0.0011 18.8 0.2 0.43 10.4 0.0 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KEZ39135.1 - 0.006 16.2 0.5 0.11 12.2 0.1 2.1 1 1 1 2 2 2 2 Beta/Gamma crystallin Arginase PF00491.16 KEZ39136.1 - 2.2e-74 250.2 0.0 2.9e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KEZ39136.1 - 0.053 13.7 0.1 0.092 12.9 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain Defensin_propep PF00879.13 KEZ39136.1 - 0.61 10.0 3.7 1.2 9.1 2.6 1.5 1 0 0 1 1 1 0 Defensin propeptide NmrA PF05368.8 KEZ39138.1 - 3.1e-34 118.2 0.0 3.5e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ39138.1 - 1.4e-10 41.4 0.2 3e-10 40.3 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEZ39138.1 - 1.5e-07 30.7 0.1 2.2e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KEZ39138.1 - 1.6e-05 25.1 0.1 2.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KEZ39138.1 - 0.02 14.3 0.1 0.088 12.2 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KEZ39138.1 - 0.079 12.6 0.2 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 KR domain Pox_Ag35 PF03286.9 KEZ39138.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4360 PF14273.1 KEZ39139.1 - 6.5e-50 169.3 0.0 1.1e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Fungal_trans PF04082.13 KEZ39139.1 - 1.3e-07 30.7 5.1 2e-07 30.1 3.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 KEZ39140.1 - 9.1e-08 32.3 0.1 3.4e-07 30.4 0.0 1.6 1 1 1 2 2 2 1 NADH(P)-binding Ricin_B_lectin PF00652.17 KEZ39141.1 - 7.7e-12 45.3 1.3 1.7e-11 44.2 0.9 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KEZ39141.1 - 4.6e-07 30.1 3.1 6.3e-05 23.2 0.3 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Sugar_tr PF00083.19 KEZ39142.1 - 7.5e-72 242.3 15.8 8.6e-72 242.1 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39142.1 - 1.2e-29 103.1 20.5 5e-27 94.5 7.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ39142.1 - 3.2e-06 25.7 0.7 3.2e-06 25.7 0.5 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein LacY_symp PF01306.14 KEZ39142.1 - 0.00024 19.7 3.3 0.00051 18.7 0.2 2.1 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF2085 PF09858.4 KEZ39142.1 - 2.3 8.3 8.3 0.32 11.0 0.1 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) DUF1996 PF09362.5 KEZ39143.1 - 6.2e-86 287.8 1.2 7.3e-86 287.6 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NAD_binding_6 PF08030.7 KEZ39144.1 - 6.7e-19 68.3 0.0 1.4e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEZ39144.1 - 7.6e-15 54.6 0.0 1.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KEZ39144.1 - 2.2e-13 50.4 14.6 2.2e-13 50.4 10.1 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KEZ39144.1 - 0.0019 18.7 0.0 0.065 13.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF2207 PF09972.4 KEZ39144.1 - 0.37 9.3 0.9 0.58 8.6 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 KEZ39145.1 - 4.5e-13 48.6 54.3 1.5e-07 30.5 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_30 PF02055.11 KEZ39146.1 - 1.7e-18 66.1 0.4 1.2e-12 46.8 0.2 2.8 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KEZ39146.1 - 3.4e-15 55.8 0.7 7.1e-14 51.5 0.5 2.4 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 HMGL-like PF00682.14 KEZ39146.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 HMGL-like DUF3632 PF12311.3 KEZ39147.1 - 2e-24 86.3 1.0 2.9e-24 85.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 KEZ39148.1 - 4.3e-06 26.6 0.0 8.2e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 ribonuclease DIM PF08194.7 KEZ39148.1 - 0.0026 17.6 0.9 0.0054 16.6 0.6 1.5 1 0 0 1 1 1 1 DIM protein FMO-like PF00743.14 KEZ39149.1 - 9.2e-23 80.2 0.0 1e-11 43.7 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEZ39149.1 - 1.9e-09 37.8 0.0 5.1e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ39149.1 - 4.4e-06 25.8 0.0 4.7e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEZ39150.1 - 8.5e-13 48.1 0.0 1.8e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ39150.1 - 3.4e-07 30.5 0.3 1.2e-06 28.7 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ39150.1 - 4.8e-07 29.1 0.0 8.5e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KEZ39150.1 - 7.5e-07 28.5 0.1 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEZ39150.1 - 9.4e-07 28.1 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KEZ39150.1 - 2.1e-06 26.8 1.0 3.6e-06 26.0 0.5 1.4 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ39150.1 - 2.9e-06 26.0 1.1 4.3e-06 25.4 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ39150.1 - 5.7e-06 26.3 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ39150.1 - 3.7e-05 22.9 0.4 5.9e-05 22.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KEZ39150.1 - 0.00047 19.1 0.1 0.0011 17.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ39150.1 - 0.0042 17.4 0.1 0.008 16.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KEZ39150.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 KEZ39150.1 - 0.016 14.0 0.5 0.024 13.5 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KEZ39150.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KEZ39150.1 - 0.04 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 KEZ39150.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 KEZ39150.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 KEZ39150.1 - 0.082 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 KEZ39150.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KEZ39150.1 - 0.17 10.7 0.2 0.28 10.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FMO-like PF00743.14 KEZ39150.1 - 0.19 9.8 0.1 0.27 9.4 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like ADH_zinc_N PF00107.21 KEZ39151.1 - 2.8e-27 94.8 1.1 4.2e-27 94.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ39151.1 - 6.5e-14 52.9 0.0 2.1e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ39151.1 - 5.1e-05 22.9 0.1 0.00015 21.5 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KEZ39151.1 - 0.0069 16.3 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain MFS_1 PF07690.11 KEZ39152.1 - 1.3e-16 60.2 7.4 1.9e-16 59.7 5.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39152.1 - 1.5e-05 23.7 3.2 1.9e-05 23.4 2.2 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KEZ39152.1 - 0.022 12.9 9.6 0.0055 14.8 4.1 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_2 PF13347.1 KEZ39152.1 - 0.21 9.9 9.8 0.44 8.8 6.8 1.5 1 1 0 1 1 1 0 MFS/sugar transport protein ATG22 PF11700.3 KEZ39152.1 - 6 5.2 11.5 12 4.2 8.0 1.4 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like AMP-binding PF00501.23 KEZ39153.1 - 7.6e-47 159.6 0.0 1e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FAA_hydrolase PF01557.13 KEZ39154.1 - 4.3e-31 108.0 0.0 6.2e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.17 KEZ39155.1 - 1e-65 222.1 0.0 3.6e-50 170.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 2-oxoacid_dh PF00198.18 KEZ39156.1 - 4.9e-66 222.3 0.1 7.4e-66 221.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEZ39156.1 - 4e-17 61.6 0.0 7.8e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEZ39156.1 - 5.7e-15 54.6 0.1 1.4e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KEZ39156.1 - 1.6e-06 27.6 0.0 0.0015 18.1 0.0 2.8 2 1 1 3 3 3 2 Biotin-lipoyl like E1_dh PF00676.15 KEZ39157.1 - 2.6e-72 243.0 0.0 3.5e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KEZ39157.1 - 0.022 13.6 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 KEZ39158.1 - 6.1e-43 146.3 0.0 8.4e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEZ39158.1 - 3e-31 107.9 0.0 5.8e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_3 PF01494.14 KEZ39159.1 - 1e-64 218.8 0.0 1.7e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEZ39159.1 - 2.2e-05 24.7 0.0 0.27 11.6 0.0 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ39159.1 - 3e-05 23.1 0.0 0.049 12.5 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ39159.1 - 0.14 12.1 0.0 1.1 9.2 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_21 PF13506.1 KEZ39160.1 - 0.0058 15.9 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Flagellin_N PF00669.15 KEZ39160.1 - 0.037 13.8 0.9 0.098 12.4 0.1 1.8 1 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF948 PF06103.6 KEZ39160.1 - 0.04 13.7 7.8 0.075 12.8 0.5 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KEZ39160.1 - 0.045 12.9 3.8 0.3 10.2 2.7 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 KEZ39160.1 - 2.1 8.6 5.0 10 6.4 2.4 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nop14 PF04147.7 KEZ39161.1 - 0.14 10.0 4.7 0.23 9.3 3.2 1.3 1 0 0 1 1 1 0 Nop14-like family Fer4_19 PF06902.6 KEZ39161.1 - 0.37 10.6 2.5 0.85 9.4 1.7 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Nucleoplasmin PF03066.10 KEZ39161.1 - 2.8 7.4 11.0 0.18 11.3 2.7 2.4 3 0 0 3 3 3 0 Nucleoplasmin DUF2196 PF09962.4 KEZ39162.1 - 1.6e-21 75.8 4.5 2.5e-21 75.2 3.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Methyltransf_24 PF13578.1 KEZ39163.1 - 5.2e-13 49.7 0.0 9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEZ39163.1 - 7.9e-09 34.8 0.0 2.1e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEZ39163.1 - 0.022 15.3 0.0 0.051 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 KEZ39164.1 - 1.6e-15 56.6 15.1 1e-10 40.8 4.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ39164.1 - 0.043 12.1 8.8 0.01 14.2 1.4 2.3 3 0 0 3 3 3 0 MFS/sugar transport protein ABC_tran PF00005.22 KEZ39165.1 - 3.3e-40 137.5 0.0 1.2e-28 100.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ39165.1 - 1.3e-09 37.8 31.1 1.8e-09 37.4 5.9 3.8 3 1 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 KEZ39165.1 - 4.8e-05 23.4 5.1 0.028 14.4 0.0 3.7 3 1 1 4 4 4 2 AAA domain T2SE PF00437.15 KEZ39165.1 - 0.00023 20.1 0.7 0.052 12.4 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KEZ39165.1 - 0.00027 20.8 0.0 0.024 14.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ39165.1 - 0.00029 20.0 0.4 0.0027 16.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ39165.1 - 0.0003 20.9 0.6 0.02 15.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain Guanylate_kin PF00625.16 KEZ39165.1 - 0.0003 20.2 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase AAA_29 PF13555.1 KEZ39165.1 - 0.00033 20.1 2.0 0.11 12.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ39165.1 - 0.00038 20.5 0.1 0.0048 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KEZ39165.1 - 0.00072 19.0 0.1 0.81 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KEZ39165.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin family AAA_14 PF13173.1 KEZ39165.1 - 0.0018 18.1 0.0 0.0051 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEZ39165.1 - 0.0023 18.1 0.3 0.013 15.7 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KEZ39165.1 - 0.0026 16.9 0.7 0.0086 15.1 0.1 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 KEZ39165.1 - 0.0026 18.0 0.0 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KEZ39165.1 - 0.0033 17.9 0.1 0.097 13.1 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 KEZ39165.1 - 0.004 16.6 0.5 0.0082 15.6 0.0 1.8 2 0 0 2 2 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 KEZ39165.1 - 0.0044 16.2 3.5 1.3 8.1 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 KEZ39165.1 - 0.006 16.4 0.3 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEZ39165.1 - 0.007 15.8 1.0 0.67 9.3 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain DUF815 PF05673.8 KEZ39165.1 - 0.011 14.6 0.3 0.035 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEZ39165.1 - 0.011 16.4 1.5 0.15 12.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KEZ39165.1 - 0.012 14.7 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 KEZ39165.1 - 0.02 15.2 1.5 0.12 12.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEZ39165.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase NB-ARC PF00931.17 KEZ39165.1 - 0.05 12.4 2.0 0.31 9.8 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 KEZ39165.1 - 0.077 12.6 0.6 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KEZ39165.1 - 0.088 12.3 1.7 2.1 7.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ39165.1 - 0.12 12.5 0.1 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 KEZ39165.1 - 0.14 11.8 1.2 0.34 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KEZ39165.1 - 0.17 11.3 1.1 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 KEZ39165.1 - 0.19 11.3 2.7 0.26 10.9 0.1 2.4 3 0 0 3 3 2 0 NACHT domain Rad17 PF03215.10 KEZ39165.1 - 0.26 9.9 0.3 0.41 9.2 0.2 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein cobW PF02492.14 KEZ39165.1 - 0.26 10.6 1.5 0.26 10.6 0.1 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEZ39165.1 - 0.4 10.3 1.8 2 8.1 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AA_permease_2 PF13520.1 KEZ39166.1 - 8.4e-93 311.2 39.7 1.1e-92 310.8 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ39166.1 - 2.9e-21 75.3 31.1 4e-21 74.9 21.6 1.2 1 0 0 1 1 1 1 Amino acid permease YCII PF03795.9 KEZ39167.1 - 8.1e-11 41.9 0.0 1.3e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 YCII-related domain Abhydrolase_4 PF08386.5 KEZ39168.1 - 5.9e-20 71.0 0.0 1.1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEZ39168.1 - 5e-13 49.1 0.0 2.1e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ39168.1 - 2.9e-07 30.6 0.0 1.3e-06 28.4 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 KEZ39169.1 - 1.5e-11 43.7 0.0 2.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ39170.1 - 8.8e-21 73.9 24.5 1.1e-20 73.6 17.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39170.1 - 1.1e-17 63.8 9.6 2.1e-17 62.8 6.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TPR_19 PF14559.1 KEZ39170.1 - 0.15 12.4 0.1 0.43 10.9 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ39170.1 - 0.16 11.8 0.2 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_11 PF00457.12 KEZ39171.1 - 2.3e-76 255.2 21.6 2.7e-76 255.0 15.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ribosomal_S16 PF00886.14 KEZ39171.1 - 0.072 12.8 0.1 0.78 9.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S16 GMC_oxred_N PF00732.14 KEZ39176.1 - 5.3e-68 229.3 0.0 7.2e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39176.1 - 5.5e-28 98.0 0.0 8.9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ39176.1 - 3.4e-06 26.1 0.4 0.052 12.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEZ39176.1 - 2.4e-05 23.4 0.3 4.4e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ39176.1 - 3.8e-05 23.6 0.1 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ39176.1 - 0.00015 20.7 2.7 0.0097 14.8 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ39176.1 - 0.012 14.7 1.1 0.019 14.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 KEZ39176.1 - 0.061 11.9 0.2 0.091 11.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HET PF06985.6 KEZ39177.1 - 0.0017 18.4 0.0 0.0052 16.9 0.0 1.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEZ39178.1 - 4.8e-36 122.9 0.1 5.2e-12 45.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ39178.1 - 4.9e-28 95.5 0.2 1.7e-08 33.8 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KEZ39178.1 - 1.2e-24 85.7 0.5 1e-07 31.9 0.1 5.3 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ39178.1 - 8.4e-23 80.3 0.0 2.1e-05 24.9 0.0 5.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ39178.1 - 7.6e-21 72.1 0.1 5.2e-07 29.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat TPR_12 PF13424.1 KEZ39178.1 - 7e-07 29.0 0.1 0.021 14.7 0.0 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ39178.1 - 0.0073 16.0 0.1 7.1 6.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ39178.1 - 0.063 13.2 0.8 5.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KEZ39179.1 - 1.9e-60 204.7 0.4 2.8e-60 204.1 0.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 KEZ39180.1 - 1.7e-08 33.6 0.0 4.9e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 KEZ39181.1 - 3.5e-78 262.8 28.7 2.2e-41 142.0 5.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ39181.1 - 2.7e-70 235.0 0.0 1.3e-34 119.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEZ39181.1 - 3.7e-12 46.8 0.0 0.0021 18.1 0.0 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KEZ39181.1 - 4.6e-11 42.3 7.8 0.00015 21.1 0.8 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KEZ39181.1 - 6.5e-10 38.1 1.5 0.00014 20.6 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KEZ39181.1 - 4.4e-09 35.7 1.4 0.00025 20.5 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEZ39181.1 - 1.1e-07 31.1 0.1 0.011 14.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ39181.1 - 1.6e-07 31.4 3.2 0.00064 19.7 0.1 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KEZ39181.1 - 1e-06 28.9 1.7 0.15 12.1 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEZ39181.1 - 3.2e-06 26.6 0.7 0.042 13.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEZ39181.1 - 1.5e-05 25.8 0.0 0.22 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEZ39181.1 - 3.2e-05 23.5 3.0 0.84 9.1 0.1 4.3 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 KEZ39181.1 - 4.6e-05 22.6 0.4 1.3 8.0 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin SbcCD_C PF13558.1 KEZ39181.1 - 0.00022 21.0 1.7 0.35 10.8 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 KEZ39181.1 - 0.00027 19.7 0.0 0.29 9.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.9 KEZ39181.1 - 0.00085 19.0 0.4 4.4 7.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KEZ39181.1 - 0.0025 18.0 0.1 7.8 6.7 0.0 4.0 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KEZ39181.1 - 0.0032 16.9 1.6 2.2 7.6 0.0 4.1 4 0 0 4 4 4 1 AAA-like domain AAA_14 PF13173.1 KEZ39181.1 - 0.0032 17.3 0.0 8.9 6.2 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.1 KEZ39181.1 - 0.0038 17.1 0.0 3.3 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KEZ39181.1 - 0.0041 17.4 0.7 0.77 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KEZ39181.1 - 0.0076 15.7 0.0 0.16 11.4 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 KEZ39181.1 - 0.012 15.3 0.1 14 5.4 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KEZ39181.1 - 0.012 14.7 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 KEZ39181.1 - 0.016 15.4 0.1 9.7 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KEZ39181.1 - 0.029 14.3 0.3 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.13 KEZ39181.1 - 0.035 13.6 0.1 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 KEZ39181.1 - 0.04 12.7 1.1 1.3 7.8 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF2207 PF09972.4 KEZ39181.1 - 0.045 12.3 0.6 0.2 10.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF815 PF05673.8 KEZ39181.1 - 0.046 12.6 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.15 KEZ39181.1 - 0.051 13.2 0.2 5.8 6.5 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase Miro PF08477.8 KEZ39181.1 - 0.06 13.8 0.2 16 6.0 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein DUF87 PF01935.12 KEZ39181.1 - 0.1 12.3 1.3 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 FumaraseC_C PF10415.4 KEZ39181.1 - 0.15 12.1 2.1 0.3 11.2 0.5 2.3 2 0 0 2 2 1 0 Fumarase C C-terminus AA_permease PF00324.16 KEZ39182.1 - 8.7e-121 403.5 43.8 1.1e-120 403.2 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ39182.1 - 1.1e-29 103.2 49.0 1.4e-29 102.9 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.11 KEZ39183.1 - 2.1e-27 96.4 0.0 2.6e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.1 KEZ39183.1 - 0.11 11.4 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus Mg_trans_NIPA PF05653.9 KEZ39184.1 - 6e-94 314.3 24.8 8.4e-94 313.8 17.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KEZ39184.1 - 4.4e-07 30.0 5.7 4.4e-07 30.0 4.0 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KEZ39184.1 - 2.2e-06 27.7 8.0 2.2e-06 27.7 5.6 3.0 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 KEZ39184.1 - 0.0038 16.1 4.6 0.0038 16.1 3.2 2.3 1 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Polysacc_deac_1 PF01522.16 KEZ39185.1 - 4.8e-28 97.2 0.0 8.6e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Terpene_synth_C PF03936.11 KEZ39186.1 - 2e-09 37.1 0.9 4e-09 36.1 0.2 1.6 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain Glyco_hydro_16 PF00722.16 KEZ39187.1 - 1.3e-06 27.8 0.1 2e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Polysacc_lyase PF14099.1 KEZ39187.1 - 0.026 14.2 0.5 0.17 11.4 0.3 2.0 1 1 0 1 1 1 0 Polysaccharide lyase Cu-oxidase_3 PF07732.10 KEZ39188.1 - 5.2e-42 142.2 8.5 1e-41 141.3 0.4 4.0 4 1 1 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEZ39188.1 - 2.1e-40 137.4 7.5 5.1e-37 126.4 0.5 3.4 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KEZ39188.1 - 7e-31 107.2 0.0 2.8e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Tropomyosin PF00261.15 KEZ39189.1 - 0.0011 18.0 36.6 0.0011 18.0 25.4 5.7 4 1 1 5 5 5 2 Tropomyosin PAM2 PF07145.10 KEZ39189.1 - 0.026 13.9 15.4 0.72 9.4 1.4 4.6 4 0 0 4 4 4 0 Ataxin-2 C-terminal region DNA_pol_B PF00136.16 KEZ39190.1 - 1.5e-95 320.7 0.0 1e-94 317.9 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KEZ39190.1 - 4.6e-21 75.0 0.0 3.4e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KEZ39190.1 - 1.2e-16 60.4 1.8 2.6e-16 59.3 1.3 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 KEZ39190.1 - 0.049 13.4 0.2 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 KEZ39190.1 - 2.8 7.6 5.6 12 5.6 0.1 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Mcp5_PH PF12814.2 KEZ39191.1 - 8e-44 148.4 0.6 1.7e-43 147.4 0.0 1.9 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Thioredoxin_2 PF13098.1 KEZ39192.1 - 0.00015 21.9 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 KEZ39192.1 - 0.00016 21.3 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KEZ39192.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF953 PF06110.6 KEZ39192.1 - 0.036 13.5 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) MFS_1 PF07690.11 KEZ39193.1 - 1.5e-38 132.4 30.6 3.4e-30 104.9 6.9 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39193.1 - 2e-12 46.4 14.7 2e-12 46.4 10.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KEZ39193.1 - 0.00019 19.8 5.0 0.00037 18.8 3.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PFK PF00365.15 KEZ39194.1 - 2.7e-161 535.1 2.6 4.5e-118 393.3 1.6 2.2 2 0 0 2 2 2 2 Phosphofructokinase EI24 PF07264.6 KEZ39195.1 - 9.7e-07 28.4 16.1 4.8e-06 26.1 11.1 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ESSS PF10183.4 KEZ39195.1 - 0.13 12.7 1.1 15 6.0 0.0 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-RING_2 PF13639.1 KEZ39196.1 - 3.6e-13 49.1 5.6 5.8e-13 48.4 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KEZ39196.1 - 4.4e-12 45.5 0.0 1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 KEZ39196.1 - 9.9e-09 35.1 2.6 1.9e-08 34.2 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEZ39196.1 - 1.4e-08 34.6 5.8 2.2e-08 33.9 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ39196.1 - 2.5e-08 33.4 3.0 3.8e-08 32.8 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ39196.1 - 2e-07 30.5 3.3 3e-07 29.9 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ39196.1 - 2.6e-07 30.2 2.2 4e-07 29.6 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KEZ39196.1 - 0.0037 17.0 1.1 0.0068 16.2 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KEZ39196.1 - 0.099 12.5 4.6 0.44 10.4 3.2 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KEZ39196.1 - 0.22 11.5 2.2 0.61 10.0 1.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KEZ39196.1 - 0.39 10.4 2.9 0.86 9.3 2.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 KEZ39196.1 - 0.63 10.1 3.6 1.2 9.2 2.5 1.5 1 0 0 1 1 1 0 RING-variant domain LANC_like PF05147.8 KEZ39197.1 - 1e-26 93.3 0.0 1.5e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein TRP PF06011.7 KEZ39199.1 - 9.1e-70 235.4 12.7 8.8e-68 228.8 8.8 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEZ39199.1 - 2.9e-19 69.5 0.0 4.2e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 ML-like domain PAR1 PF06521.6 KEZ39199.1 - 0.23 11.0 0.0 0.51 9.9 0.0 1.4 1 0 0 1 1 1 0 PAR1 protein ATP-sulfurylase PF01747.12 KEZ39200.1 - 3.5e-88 294.5 0.2 4.7e-88 294.0 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KEZ39200.1 - 2.1e-57 193.1 0.0 3.4e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KEZ39200.1 - 2.8e-51 173.0 0.0 4.3e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 KEZ39200.1 - 0.041 13.7 0.2 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KEZ39200.1 - 0.056 12.6 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Dioxygenase_C PF00775.16 KEZ39201.1 - 1.2e-53 181.0 0.0 1.8e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEZ39201.1 - 2e-14 53.3 0.0 8.9e-14 51.2 0.0 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEZ39201.1 - 0.0013 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF824 PF05688.6 KEZ39201.1 - 0.051 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) SUI1 PF01253.17 KEZ39202.1 - 3.4e-29 100.4 6.4 4.3e-29 100.1 4.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 KEZ39202.1 - 0.17 11.9 0.6 0.34 10.9 0.1 1.6 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) EOS1 PF12326.3 KEZ39203.1 - 2.7e-22 79.0 11.2 1.5e-19 70.1 3.2 2.3 1 1 1 2 2 2 2 N-glycosylation protein CAF-1_p60_C PF15512.1 KEZ39203.1 - 0.047 14.1 10.6 0.064 13.6 7.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal DUF566 PF04484.7 KEZ39203.1 - 2.4 7.6 7.4 3.5 7.0 5.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Tim44 PF04280.10 KEZ39204.1 - 1.1e-08 35.2 0.8 6.5e-08 32.6 0.1 2.3 2 1 0 2 2 2 1 Tim44-like domain MBA1 PF07961.6 KEZ39204.1 - 3.7e-06 25.9 0.0 1.5e-05 23.9 0.0 1.8 1 1 1 2 2 2 1 MBA1-like protein SSF PF00474.12 KEZ39205.1 - 7.7e-06 24.7 31.5 0.00012 20.8 21.9 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family Tom22 PF04281.8 KEZ39205.1 - 0.34 10.4 0.8 0.84 9.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 RRM_1 PF00076.17 KEZ39206.1 - 2.6e-19 68.6 0.0 3.2e-12 45.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ39206.1 - 7.6e-17 61.0 0.0 3.5e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ39206.1 - 3.1e-12 46.1 0.0 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 KEZ39207.1 - 2.9e-44 150.6 0.0 4.7e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Sas10_Utp3 PF04000.10 KEZ39208.1 - 3e-08 33.7 0.4 6.7e-08 32.6 0.3 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Seryl_tRNA_N PF02403.17 KEZ39208.1 - 0.053 13.5 6.9 0.33 10.9 0.2 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2076 PF09849.4 KEZ39210.1 - 1.1e-09 38.7 9.7 1.3e-09 38.5 6.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KEZ39210.1 - 0.00011 21.9 4.8 0.00017 21.4 3.3 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 KEZ39210.1 - 0.012 15.7 0.9 0.02 15.0 0.2 1.6 1 1 1 2 2 2 0 GCK domain COX6B PF02297.12 KEZ39210.1 - 0.29 11.1 3.4 0.4 10.7 2.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Gly-zipper_YMGG PF13441.1 KEZ39210.1 - 4.2 6.9 12.0 0.98 8.9 6.1 1.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper UBX PF00789.15 KEZ39211.1 - 1.2e-08 34.8 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 KEZ39211.1 - 0.0064 16.4 0.1 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like CDC27 PF09507.5 KEZ39211.1 - 0.088 12.0 28.3 0.15 11.2 19.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.4 KEZ39211.1 - 10 4.2 12.8 18 3.4 8.9 1.4 1 0 0 1 1 1 0 Transmembrane protein SURF1 PF02104.10 KEZ39212.1 - 4.5e-66 222.7 0.0 5.7e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 KEZ39213.1 - 3e-99 333.1 14.7 4.8e-57 194.0 8.6 2.3 1 1 1 2 2 2 2 Centromere kinetochore component CENP-T CENP-S PF15630.1 KEZ39213.1 - 1.1e-09 38.3 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEZ39213.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEZ39213.1 - 0.00071 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KEZ39213.1 - 0.013 15.1 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 KEZ39213.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Ras PF00071.17 KEZ39214.1 - 5.2e-54 181.9 0.0 6e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ39214.1 - 7.9e-18 65.0 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ39214.1 - 1.6e-06 27.4 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CMS1 PF14617.1 KEZ39215.1 - 1.5e-83 279.7 0.3 1.5e-83 279.7 0.2 4.6 3 1 1 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit RRM_1 PF00076.17 KEZ39215.1 - 4.8e-12 45.3 0.0 1.2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ39215.1 - 3.9e-09 36.3 0.0 8.9e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 KEZ39215.1 - 3.7e-06 26.5 0.0 8.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_5 PF13893.1 KEZ39215.1 - 0.0041 16.9 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.22 KEZ39216.1 - 4.2e-46 156.3 0.0 1.2e-45 154.8 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KEZ39216.1 - 1.3e-14 54.1 0.3 4.1e-14 52.5 0.2 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DnaI_N PF07319.6 KEZ39216.1 - 0.11 12.7 0.6 0.38 11.0 0.1 2.1 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Med12 PF09497.5 KEZ39217.1 - 2.1e-27 94.8 0.4 8.4e-27 92.9 0.2 2.2 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 UPF0139 PF03669.8 KEZ39218.1 - 0.00043 19.7 0.1 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Asp PF00026.18 KEZ39219.1 - 3.7e-62 210.4 1.4 4.5e-62 210.1 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ39219.1 - 8e-11 42.1 0.0 3.2e-10 40.1 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEZ39219.1 - 3.4e-06 27.4 0.1 0.047 14.1 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KEZ39219.1 - 0.0032 17.0 0.2 0.96 8.9 0.0 2.5 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KEZ39219.1 - 0.059 13.2 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Serglycin PF04360.7 KEZ39219.1 - 0.075 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Serglycin Mt_ATP-synt_D PF05873.7 KEZ39220.1 - 1.1e-16 60.9 2.9 1.3e-16 60.6 2.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Dor1 PF04124.7 KEZ39220.1 - 0.0037 15.7 2.4 0.0047 15.4 1.6 1.2 1 0 0 1 1 1 1 Dor1-like family DUF2775 PF10950.3 KEZ39220.1 - 0.11 12.7 1.2 0.15 12.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2775) YodL PF14191.1 KEZ39220.1 - 0.14 12.6 0.4 0.41 11.1 0.1 1.8 2 0 0 2 2 2 0 YodL-like DUF3074 PF11274.3 KEZ39220.1 - 0.18 11.4 0.9 0.25 10.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) Phage_GP20 PF06810.6 KEZ39220.1 - 0.22 10.9 8.9 0.13 11.7 0.6 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4515 PF14988.1 KEZ39220.1 - 0.23 11.1 7.3 2 8.0 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4515) CheZ PF04344.8 KEZ39220.1 - 0.25 10.9 5.2 0.42 10.2 3.6 1.3 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ V_ATPase_I PF01496.14 KEZ39220.1 - 0.37 8.5 2.7 0.44 8.3 1.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2408 PF10303.4 KEZ39220.1 - 0.54 10.3 4.2 0.54 10.3 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Spectrin PF00435.16 KEZ39220.1 - 0.63 10.3 7.5 2.2 8.5 0.6 2.4 1 1 2 3 3 3 0 Spectrin repeat CCP_MauG PF03150.9 KEZ39220.1 - 0.68 10.2 3.5 0.86 9.8 2.0 1.5 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase TMF_DNA_bd PF12329.3 KEZ39220.1 - 1.3 8.9 6.9 4.3 7.2 1.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Neuromodulin PF06614.6 KEZ39220.1 - 6.7 6.6 7.3 3.3 7.6 3.6 1.5 1 1 1 2 2 2 0 Neuromodulin WD40 PF00400.27 KEZ39221.1 - 8.2e-13 47.7 15.7 9.7e-06 25.2 0.6 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat RWD PF05773.17 KEZ39221.1 - 0.00092 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 KEZ39221.1 - 0.038 13.4 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.1 KEZ39221.1 - 0.88 9.4 9.4 1.9 8.4 6.5 1.5 1 0 0 1 1 1 0 Ring finger domain UQ_con PF00179.21 KEZ39222.1 - 9.3e-49 164.4 0.0 1.1e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ39222.1 - 0.0001 22.0 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KEZ39222.1 - 0.0036 16.9 0.1 0.0072 16.0 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KEZ39222.1 - 0.035 14.0 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain ADH_zinc_N PF00107.21 KEZ39223.1 - 1.8e-13 50.1 0.0 3.4e-13 49.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ39223.1 - 0.00035 20.2 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PI3Ka PF00613.15 KEZ39224.1 - 4.1e-57 192.3 0.3 7.2e-57 191.5 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KEZ39224.1 - 5.8e-45 153.5 0.0 1.5e-43 148.9 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KEZ39224.1 - 7e-33 113.4 0.0 1.1e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 SrfB PF07520.6 KEZ39224.1 - 0.061 10.8 0.1 0.088 10.2 0.1 1.1 1 0 0 1 1 1 0 Virulence factor SrfB Nse4_C PF08743.5 KEZ39225.1 - 3.3e-34 116.7 0.0 6.4e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KEZ39225.1 - 1.5e-17 63.2 0.0 3.8e-17 61.8 0.0 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Pox_Ag35 PF03286.9 KEZ39225.1 - 0.0019 17.7 1.1 0.017 14.6 0.5 2.2 2 0 0 2 2 2 1 Pox virus Ag35 surface protein DUF1409 PF07197.7 KEZ39225.1 - 0.015 15.3 1.3 0.043 13.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) DUF3326 PF11805.3 KEZ39225.1 - 0.03 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) ASD2 PF08687.6 KEZ39225.1 - 0.045 13.0 1.0 0.064 12.5 0.1 1.7 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 DivIC PF04977.10 KEZ39225.1 - 0.06 12.8 0.3 0.16 11.4 0.2 1.7 1 0 0 1 1 1 0 Septum formation initiator tRNA-synt_2 PF00152.15 KEZ39226.1 - 3e-72 243.2 0.0 4.3e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEZ39226.1 - 0.00024 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Borrelia_P83 PF05262.6 KEZ39226.1 - 0.3 9.3 6.3 0.47 8.6 4.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein NARP1 PF12569.3 KEZ39226.1 - 0.51 9.0 7.9 0.67 8.6 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Fasciclin PF02469.17 KEZ39227.1 - 1.3e-44 151.3 0.0 2.4e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Pal1 PF08316.6 KEZ39228.1 - 1.3e-41 142.3 2.3 1.3e-41 142.3 1.6 2.5 2 1 0 2 2 2 1 Pal1 cell morphology protein DUF3154 PF11351.3 KEZ39228.1 - 0.016 14.9 0.1 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) vMSA PF00695.14 KEZ39228.1 - 4.6 6.3 8.1 0.071 12.3 0.1 1.8 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus DUF3764 PF12594.3 KEZ39229.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) DUF3433 PF11915.3 KEZ39230.1 - 4.4e-30 103.6 17.2 1.1e-29 102.3 0.5 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF3433) Raptor_N PF14538.1 KEZ39234.1 - 6.8e-64 214.3 0.0 1.3e-63 213.4 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KEZ39234.1 - 1.9e-09 37.0 1.2 0.48 10.3 0.0 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEZ39234.1 - 6.9e-05 22.5 0.1 0.13 12.0 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 KEZ39234.1 - 0.0024 18.1 0.4 0.59 10.4 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 KEZ39234.1 - 0.003 17.4 6.6 2.7 8.3 0.1 5.5 6 0 0 6 6 6 1 HEAT repeat Kelch_4 PF13418.1 KEZ39235.1 - 4.8e-38 128.6 9.6 4.4e-07 29.5 0.2 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KEZ39235.1 - 9e-31 105.3 11.7 1.1e-07 31.6 0.1 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 KEZ39235.1 - 6.9e-29 98.8 5.8 8.9e-09 35.1 0.4 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KEZ39235.1 - 2.6e-28 97.2 4.1 4.7e-09 35.6 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 KEZ39235.1 - 1.2e-27 95.3 22.8 1.9e-08 34.2 0.1 7.1 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KEZ39235.1 - 8.5e-18 63.3 7.9 2.8e-05 23.6 0.1 7.1 6 1 0 6 6 6 5 Kelch motif RAG2 PF03089.9 KEZ39235.1 - 0.2 10.3 0.2 3.1 6.4 0.0 2.9 4 0 0 4 4 4 0 Recombination activating protein 2 CFEM PF05730.6 KEZ39236.1 - 8.8e-05 22.2 2.0 8.8e-05 22.2 1.4 2.3 2 0 0 2 2 2 1 CFEM domain Ank_5 PF13857.1 KEZ39237.1 - 3e-05 24.1 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEZ39237.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ39237.1 - 0.024 14.4 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat HSP70 PF00012.15 KEZ39238.1 - 0.071 11.0 0.4 0.5 8.2 0.1 2.3 2 1 0 2 2 2 0 Hsp70 protein AAA_13 PF13166.1 KEZ39239.1 - 0.025 13.0 1.5 0.037 12.5 1.0 1.1 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.2 KEZ39239.1 - 0.11 11.7 7.1 0.21 10.9 4.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CENP-Q PF13094.1 KEZ39239.1 - 0.12 12.3 4.9 0.28 11.1 3.4 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 KEZ39239.1 - 0.27 11.0 7.0 1 9.2 0.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KEZ39239.1 - 0.39 10.2 7.4 0.89 9.1 5.1 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KEZ39239.1 - 0.46 8.2 2.7 0.68 7.7 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 KEZ39239.1 - 3.1 7.7 4.8 33 4.4 0.5 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 KEZ39239.1 - 3.2 7.2 7.2 1.1 8.8 1.2 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uds1 PF15456.1 KEZ39239.1 - 8 6.4 11.3 0.95 9.4 2.8 2.8 1 1 1 2 2 2 0 Up-regulated During Septation PTR2 PF00854.16 KEZ39240.1 - 6e-48 163.5 9.2 2.8e-25 88.9 2.7 3.0 2 1 1 3 3 3 2 POT family DUF1689 PF07954.6 KEZ39240.1 - 0.017 14.9 0.7 0.39 10.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1689) Glyco_hydro_6 PF01341.12 KEZ39241.1 - 1.2e-95 320.3 0.0 1.5e-95 320.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 AP_endonuc_2 PF01261.19 KEZ39241.1 - 0.05 12.8 0.1 0.086 12.1 0.1 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PI3_PI4_kinase PF00454.22 KEZ39242.1 - 3e-47 161.0 0.0 5.5e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KEZ39242.1 - 2.9e-29 102.1 1.9 5.3e-29 101.2 1.3 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KEZ39242.1 - 5.3e-29 100.3 0.2 5e-28 97.1 0.0 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 KEZ39242.1 - 1.5e-17 62.7 0.0 3.3e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.1 KEZ39242.1 - 0.023 15.3 1.5 1.4 9.7 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-PARP PF00645.13 KEZ39243.1 - 1.6e-14 53.8 0.4 5.2e-14 52.2 0.3 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Med17 PF10156.4 KEZ39246.1 - 1e-68 231.7 0.0 1.3e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PI-PLC-X PF00388.14 KEZ39247.1 - 3.2e-53 179.0 0.0 5.9e-53 178.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEZ39247.1 - 2.2e-34 117.9 0.0 4.1e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KEZ39247.1 - 0.0033 17.4 0.1 0.0085 16.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like zf-C2H2 PF00096.21 KEZ39248.1 - 1.3e-09 37.7 9.7 0.00012 22.2 0.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ39248.1 - 8.1e-07 28.9 18.6 0.0001 22.3 0.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 KEZ39248.1 - 2.9e-06 27.1 10.3 2.9e-06 27.1 7.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 KEZ39248.1 - 0.00022 21.3 3.0 0.00022 21.3 2.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain Ribosomal_60s PF00428.14 KEZ39249.1 - 2.4 8.6 14.0 0.13 12.6 4.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein eIF-5a PF01287.15 KEZ39252.1 - 4.8e-06 26.4 0.0 8.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.3 KEZ39252.1 - 0.0098 16.4 0.9 0.0098 16.4 0.6 2.6 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red IncA PF04156.9 KEZ39253.1 - 3.3 7.2 7.4 1.2 8.7 0.3 2.8 3 0 0 3 3 3 0 IncA protein DivIC PF04977.10 KEZ39253.1 - 5 6.6 7.5 0.76 9.3 0.5 2.6 2 0 0 2 2 2 0 Septum formation initiator Myosin_head PF00063.16 KEZ39254.1 - 5.5e-251 834.4 0.0 5.5e-251 834.4 0.0 2.7 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KEZ39254.1 - 2.2e-27 95.1 282.7 2.4e-20 71.9 51.6 7.1 3 2 3 7 7 7 7 Myosin tail Myosin_N PF02736.14 KEZ39254.1 - 3.9e-05 23.2 0.2 0.00011 21.7 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 KEZ39254.1 - 0.06 13.1 0.0 0.21 11.3 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain UDPG_MGDP_dh_N PF03721.9 KEZ39254.1 - 0.36 10.1 3.3 1.2 8.4 2.3 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sec2p PF06428.6 KEZ39255.1 - 0.076 12.8 0.6 0.076 12.8 0.4 1.9 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p PHD PF00628.24 KEZ39256.1 - 1.1e-09 37.8 2.8 2.6e-09 36.6 1.9 1.6 1 0 0 1 1 1 1 PHD-finger UIM PF02809.15 KEZ39256.1 - 0.02 14.4 1.0 0.079 12.5 0.7 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif PHD_2 PF13831.1 KEZ39256.1 - 0.027 13.8 4.3 0.047 13.0 3.0 1.4 1 0 0 1 1 1 0 PHD-finger DLH PF01738.13 KEZ39259.1 - 2.2e-14 53.2 0.0 2.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ39259.1 - 2.4e-06 27.3 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ39259.1 - 0.005 16.4 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ39259.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short_C2 PF13561.1 KEZ39260.1 - 1.1e-23 84.2 0.0 1.3e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ39260.1 - 6.2e-17 62.0 6.6 1.5e-15 57.5 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 KEZ39260.1 - 6.8e-08 32.3 4.6 3.6e-07 30.0 0.0 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KEZ39260.1 - 0.0059 16.0 0.0 0.011 15.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Acyl-CoA_dh_1 PF00441.19 KEZ39262.1 - 2.4e-42 144.5 0.8 4.4e-42 143.7 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEZ39262.1 - 6.2e-31 107.3 0.0 1.3e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ39262.1 - 5.4e-18 64.2 0.0 1.2e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEZ39262.1 - 2.5e-13 50.4 0.2 4.7e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KEZ39262.1 - 3.1e-05 23.5 0.5 0.00015 21.2 0.4 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.1 KEZ39262.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Carboxyl_trans PF01039.17 KEZ39263.1 - 4.5e-142 473.8 0.1 6.3e-142 473.3 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KEZ39263.1 - 0.019 14.1 0.1 0.24 10.5 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) DUF1348 PF07080.6 KEZ39264.1 - 3.5e-25 88.4 7.8 9e-19 67.6 2.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1348) DUF3417 PF11897.3 KEZ39264.1 - 0.083 12.8 1.6 0.099 12.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Redoxin PF08534.5 KEZ39265.1 - 2e-34 118.2 0.0 2.3e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEZ39265.1 - 7.7e-10 38.5 0.0 9.6e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF295 PF03478.13 KEZ39265.1 - 0.0034 16.7 0.0 0.0062 15.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF295) Ribosomal_L24e PF01246.15 KEZ39266.1 - 1.9e-30 104.4 0.3 1.9e-30 104.4 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Phosducin PF02114.11 KEZ39267.1 - 4.5e-15 55.1 0.1 7.3e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KEZ39267.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin LRR_4 PF12799.2 KEZ39268.1 - 4.5e-13 48.4 30.7 8.1e-09 34.9 6.3 4.4 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ39268.1 - 1.8e-10 40.4 13.1 4.2e-10 39.2 2.6 3.9 3 2 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 KEZ39268.1 - 2.8e-05 23.5 22.2 0.023 14.6 0.4 6.0 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 KEZ39268.1 - 0.00025 20.7 13.6 0.16 12.3 0.2 5.3 5 0 0 5 5 5 2 Leucine rich repeat DUF1620 PF07774.8 KEZ39269.1 - 9.3e-64 214.6 0.0 1.4e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KEZ39269.1 - 3.7e-17 62.5 6.6 5.3e-13 48.9 1.1 2.8 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 KEZ39269.1 - 3.7e-09 35.6 0.4 0.00016 21.0 0.0 5.3 6 0 0 6 6 6 2 PQQ enzyme repeat EST1_DNA_bind PF10373.4 KEZ39270.1 - 5.2e-11 42.2 0.2 1.3e-10 41.0 0.1 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain SQS_PSY PF00494.14 KEZ39270.1 - 0.0057 15.9 0.4 0.037 13.3 0.1 2.3 2 0 0 2 2 2 1 Squalene/phytoene synthase ThiF PF00899.16 KEZ39271.1 - 1.3e-35 122.2 0.0 2.7e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KEZ39271.1 - 0.0065 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AAA_26 PF13500.1 KEZ39271.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Coatomer_E PF04733.9 KEZ39271.1 - 0.029 13.5 0.0 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Coatomer epsilon subunit Glyco_hydro_17 PF00332.13 KEZ39271.1 - 0.051 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 UDPG_MGDP_dh_N PF03721.9 KEZ39271.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TSGP1 PF07771.6 KEZ39273.1 - 4.9 7.0 6.3 5.6 6.8 4.4 1.1 1 0 0 1 1 1 0 Tick salivary peptide group 1 Arb2 PF09757.4 KEZ39274.1 - 7.8e-19 67.7 0.0 1.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain TFIIA PF03153.8 KEZ39277.1 - 1.7e-06 28.1 4.4 2.2e-06 27.8 3.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit VID27 PF08553.5 KEZ39277.1 - 0.17 10.0 10.6 0.23 9.6 7.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 KEZ39277.1 - 0.38 8.7 18.1 0.52 8.2 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 KEZ39277.1 - 1.6 7.2 5.5 2.3 6.7 3.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.8 KEZ39277.1 - 4.8 5.8 17.2 7 5.2 11.9 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 KEZ39277.1 - 7.6 4.3 26.6 11 3.7 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_S8 PF00082.17 KEZ39278.1 - 1.1e-52 178.9 7.9 1.7e-52 178.3 5.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEZ39278.1 - 2.2e-19 69.7 0.3 4.7e-19 68.7 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.13 KEZ39279.1 - 9.2e-111 369.6 0.3 2.7e-110 368.0 0.0 1.9 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 KEZ39279.1 - 7.3e-11 41.8 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 KEZ39279.1 - 2e-05 24.3 0.8 4.3 7.3 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat p450 PF00067.17 KEZ39280.1 - 2.2e-52 178.1 0.0 2.7e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDOST_48kD PF03345.9 KEZ39281.1 - 5.4e-159 529.2 0.0 6.1e-159 529.0 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Isy1 PF06246.7 KEZ39282.1 - 1.2e-89 300.1 0.5 1.7e-89 299.6 0.3 1.2 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 KEZ39282.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 YolD-like protein Glyco_hydro_3 PF00933.16 KEZ39283.1 - 2.6e-58 197.3 0.0 3.8e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ39283.1 - 4.4e-43 147.4 0.3 6.8e-43 146.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ39283.1 - 8.2e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Menin PF05053.8 KEZ39284.1 - 0.75 7.8 3.3 1.1 7.3 2.3 1.1 1 0 0 1 1 1 0 Menin AhpC-TSA_2 PF13911.1 KEZ39286.1 - 3e-11 43.2 0.2 1.2e-10 41.2 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KEZ39286.1 - 9.7e-05 22.0 0.0 0.00019 21.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEZ39286.1 - 0.0031 17.0 0.0 0.0099 15.4 0.0 1.8 1 1 1 2 2 2 1 Redoxin PAP_assoc PF03828.14 KEZ39287.1 - 7e-19 67.5 0.3 1.7e-18 66.2 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEZ39287.1 - 7.7e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain eIF-1a PF01176.14 KEZ39289.1 - 8.5e-27 92.3 0.3 1.2e-26 91.9 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 KEZ39289.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain WH1 PF00568.18 KEZ39290.1 - 9.9e-27 92.8 0.1 1.4e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 KEZ39290.1 - 0.003 17.1 0.3 0.0067 15.9 0.2 1.6 1 0 0 1 1 1 1 WH2 motif IBR PF01485.16 KEZ39292.1 - 1.6e-06 27.8 16.5 5.9e-05 22.8 11.5 2.8 1 1 0 1 1 1 1 IBR domain Malate_synthase PF01274.17 KEZ39292.1 - 0.0041 15.1 0.7 0.01 13.9 0.5 1.6 1 1 0 1 1 1 1 Malate synthase MmgE_PrpD PF03972.9 KEZ39293.1 - 5.1e-149 496.2 0.0 6e-149 496.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family SH3_1 PF00018.23 KEZ39294.1 - 1.4e-15 56.3 0.1 2.2e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ39294.1 - 2.6e-10 39.7 0.0 3.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEZ39294.1 - 3.7e-09 35.9 0.0 5.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.8 KEZ39294.1 - 0.027 14.5 0.2 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF910 PF06014.6 KEZ39294.1 - 0.11 12.4 0.1 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) DUF4004 PF13171.1 KEZ39294.1 - 0.15 12.1 0.1 0.64 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4004) HhH-GPD PF00730.20 KEZ39295.1 - 0.00021 21.5 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SEN1_N PF12726.2 KEZ39296.1 - 1.5e-132 443.1 0.2 2.3e-132 442.5 0.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KEZ39296.1 - 3e-66 223.3 0.4 3e-66 223.3 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KEZ39296.1 - 8.1e-63 211.4 0.1 3.4e-62 209.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ39296.1 - 3.9e-11 42.5 0.4 1e-09 38.0 0.3 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KEZ39296.1 - 3.2e-07 30.1 0.1 0.00012 21.7 0.1 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KEZ39296.1 - 5.7e-05 22.7 1.0 0.038 13.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KEZ39296.1 - 0.0048 16.3 0.1 0.014 14.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KEZ39296.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ribosomal_S27e PF01667.12 KEZ39297.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KEZ39297.1 - 0.016 15.0 1.4 0.018 14.9 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 KEZ39297.1 - 0.27 10.5 3.3 0.41 10.0 2.3 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding SIP1 PF04938.7 KEZ39298.1 - 0.0023 17.3 0.0 3.2 7.0 0.0 3.3 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Herpes_LMP2 PF07415.6 KEZ39298.1 - 0.87 8.1 12.4 0.027 13.0 4.1 1.7 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Herpes_TAF50 PF03326.8 KEZ39298.1 - 2.7 6.8 8.5 5.4 5.8 5.9 1.4 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) FAD_binding_4 PF01565.18 KEZ39299.1 - 6.3e-23 80.7 2.4 1.7e-22 79.3 1.0 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEZ39299.1 - 1.1e-12 47.6 1.1 1.7e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like WD40 PF00400.27 KEZ39301.1 - 1.2e-11 44.0 13.6 0.00016 21.3 0.1 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Nup160 PF11715.3 KEZ39301.1 - 0.021 12.9 0.6 0.26 9.3 0.0 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KEZ39301.1 - 0.1 12.8 0.0 4.7 7.6 0.0 3.5 3 1 0 3 3 3 0 PQQ-like domain Pro-kuma_activ PF09286.6 KEZ39302.1 - 6.9e-45 152.5 0.1 1.6e-44 151.3 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KEZ39302.1 - 9.7e-11 41.3 0.5 1.7e-10 40.5 0.3 1.3 1 0 0 1 1 1 1 Subtilase family Complex1_LYR_1 PF13232.1 KEZ39303.1 - 2.3e-23 82.1 2.7 3e-23 81.8 1.9 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KEZ39303.1 - 8.5e-22 76.7 2.9 1.2e-21 76.2 2.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Bac_luciferase PF00296.15 KEZ39303.1 - 0.0042 16.2 0.1 0.005 16.0 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Complex1_LYR_2 PF13233.1 KEZ39303.1 - 0.0067 16.9 0.7 0.0076 16.7 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like IL28A PF15177.1 KEZ39303.1 - 0.049 13.1 0.1 0.058 12.9 0.1 1.1 1 0 0 1 1 1 0 Interleukin-28A VitD-bind_III PF09164.5 KEZ39303.1 - 0.13 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Catalase-rel PF06628.7 KEZ39303.1 - 0.22 11.4 2.0 6.3 6.7 0.7 2.4 1 1 2 3 3 3 0 Catalase-related immune-responsive Toxin_43 PF15604.1 KEZ39303.1 - 0.24 11.4 2.5 0.26 11.2 1.7 1.1 1 0 0 1 1 1 0 Putative toxin 43 OPT PF03169.10 KEZ39305.1 - 3.4e-184 613.7 52.5 3.9e-184 613.5 36.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_GP90 PF00971.13 KEZ39305.1 - 2.7 6.3 5.8 6.7 5.0 0.0 2.4 3 0 0 3 3 3 0 EIAV coat protein, gp90 Pyridoxal_deC PF00282.14 KEZ39306.1 - 1.4e-59 201.4 0.0 2e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MFS_1 PF07690.11 KEZ39306.1 - 3.8e-42 144.2 34.1 2.7e-40 138.1 13.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39306.1 - 1.3e-08 33.8 1.9 1.3e-08 33.8 1.4 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Podoplanin PF05808.6 KEZ39306.1 - 0.00074 19.1 0.1 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 Podoplanin Aminotran_5 PF00266.14 KEZ39306.1 - 0.0014 17.4 0.0 0.0026 16.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V TRI12 PF06609.8 KEZ39306.1 - 0.0015 16.8 0.4 0.0025 16.0 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sporozoite_P67 PF05642.6 KEZ39306.1 - 0.011 13.6 4.1 0.016 13.1 2.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Rax2 PF12768.2 KEZ39306.1 - 0.026 13.7 0.6 0.054 12.7 0.4 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4064 PF13273.1 KEZ39306.1 - 0.3 11.2 5.9 1.3 9.1 0.0 3.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Macoilin PF09726.4 KEZ39306.1 - 0.77 7.9 3.9 1.2 7.3 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein Acatn PF13000.2 KEZ39307.1 - 7e-151 503.4 21.3 1.4e-77 261.4 5.7 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.5 KEZ39308.1 - 7.3e-21 74.2 1.2 1.2e-20 73.4 0.0 2.0 3 0 0 3 3 3 1 Cenp-O kinetochore centromere component DUF3999 PF13163.1 KEZ39308.1 - 0.0079 15.1 0.3 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3999) MFS_1 PF07690.11 KEZ39309.1 - 3.9e-36 124.5 44.5 3.9e-36 124.5 30.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39309.1 - 8.7e-09 34.4 37.9 4.1e-06 25.6 9.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Wbp11 PF09429.5 KEZ39310.1 - 1.7e-21 75.9 10.2 1.7e-21 75.9 7.1 2.5 3 0 0 3 3 3 1 WW domain binding protein 11 Lipoprotein_7 PF01540.11 KEZ39310.1 - 0.0094 15.0 0.7 0.014 14.5 0.5 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein DUF2294 PF10057.4 KEZ39310.1 - 0.037 13.6 0.2 0.064 12.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) Pkinase PF00069.20 KEZ39311.1 - 2.7e-58 197.1 0.0 1.8e-57 194.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39311.1 - 1.3e-28 99.8 0.4 2e-20 72.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KEZ39311.1 - 1.5e-06 28.6 0.2 4.2e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KEZ39311.1 - 0.00035 19.6 0.3 0.002 17.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KEZ39311.1 - 0.0053 16.5 0.1 0.076 12.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEZ39311.1 - 0.056 12.5 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.2 KEZ39313.1 - 6.3e-94 308.4 4.8 1.1e-17 64.0 0.0 6.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ39313.1 - 6e-70 227.7 0.1 4.2e-05 23.1 0.0 11.5 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.1 KEZ39313.1 - 1.3e-58 194.3 0.3 3.4e-11 43.3 0.0 8.1 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ39313.1 - 2.9e-55 178.6 0.0 0.002 18.1 0.0 11.8 11 0 0 11 11 11 11 Ankyrin repeat Ank_5 PF13857.1 KEZ39313.1 - 3.3e-41 138.3 0.8 8.9e-08 32.1 0.0 8.3 2 2 6 9 9 9 7 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 KEZ39313.1 - 2.5e-13 49.5 0.1 1.2e-12 47.3 0.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KEZ39313.1 - 6.4e-09 35.6 0.0 1.4e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ39313.1 - 1.5e-06 28.3 0.3 9.1e-06 25.7 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ39313.1 - 0.0015 18.6 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEZ39313.1 - 0.0049 16.3 0.0 0.048 13.0 0.0 2.4 2 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 KEZ39313.1 - 0.0057 16.9 0.0 0.047 13.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KEZ39313.1 - 0.0078 15.7 0.0 0.18 11.3 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain KAP_NTPase PF07693.9 KEZ39313.1 - 0.015 14.2 0.5 0.86 8.5 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 KEZ39313.1 - 0.052 13.8 0.0 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEZ39313.1 - 0.083 12.6 0.0 0.44 10.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain DUF3459 PF11941.3 KEZ39313.1 - 0.36 10.9 2.8 1.5e+02 2.5 0.0 4.5 1 1 3 5 5 5 0 Domain of unknown function (DUF3459) GATA PF00320.22 KEZ39315.1 - 1.7e-16 59.2 1.9 3.3e-16 58.3 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 KEZ39315.1 - 6.7e-12 44.7 0.4 1.4e-11 43.7 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Ipi1_N PF12333.3 KEZ39317.1 - 3.7e-20 71.7 0.0 2.1e-19 69.3 0.0 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation MOR2-PAG1_C PF14225.1 KEZ39317.1 - 0.0086 15.8 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Cell morphogenesis C-terminal DEAD PF00270.24 KEZ39318.1 - 8.4e-41 139.2 0.0 1.5e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ39318.1 - 3.7e-21 74.7 0.1 8.7e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aldedh PF00171.17 KEZ39319.1 - 4.6e-112 374.7 0.0 5.7e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family E1-E2_ATPase PF00122.15 KEZ39320.1 - 2.5e-13 49.5 0.0 1.5e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KEZ39320.1 - 3.1e-13 49.4 0.0 8.3e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ39320.1 - 3.2e-13 50.2 0.0 1.5e-12 48.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEZ39320.1 - 5.2e-11 43.3 2.4 1.5e-08 35.3 1.7 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ39320.1 - 0.012 15.2 0.4 0.028 13.9 0.3 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.13 KEZ39322.1 - 2.7e-54 183.4 7.2 3.1e-54 183.2 5.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Mg_trans_NIPA PF05653.9 KEZ39323.1 - 4.3e-15 55.4 11.7 9.3e-15 54.3 8.1 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KEZ39323.1 - 1.8e-05 24.7 18.4 9.6e-05 22.4 0.0 3.1 2 1 1 3 3 3 2 EamA-like transporter family COX4_pro_2 PF07835.7 KEZ39323.1 - 0.066 13.2 0.7 1.4 8.9 0.1 2.6 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF373 PF04123.8 KEZ39323.1 - 0.85 8.5 6.4 0.53 9.2 3.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Multi_Drug_Res PF00893.14 KEZ39323.1 - 1 9.8 8.9 13 6.3 0.1 2.9 2 1 0 2 2 2 0 Small Multidrug Resistance protein Tetraspannin PF00335.15 KEZ39324.1 - 0.00019 20.7 11.0 0.0004 19.7 7.6 1.7 1 1 0 1 1 1 1 Tetraspanin family SRF-TF PF00319.13 KEZ39325.1 - 8.6e-24 82.5 0.4 1.2e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 KEZ39325.1 - 0.059 11.3 0.5 0.076 11.0 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Ctr PF04145.10 KEZ39326.1 - 7.3e-30 103.9 1.0 8.9e-30 103.6 0.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.16 KEZ39326.1 - 0.43 10.2 4.7 4.3 7.0 0.2 2.2 2 0 0 2 2 2 0 PAP2 superfamily Malate_synthase PF01274.17 KEZ39327.1 - 1.7e-232 772.0 0.0 1.9e-232 771.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 KEZ39327.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Pkinase PF00069.20 KEZ39328.1 - 2.7e-71 239.7 0.0 3.9e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39328.1 - 8.3e-36 123.3 0.0 3.8e-34 117.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39328.1 - 1.8e-06 27.1 0.0 3.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ39328.1 - 0.0038 16.3 0.0 0.0084 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KEZ39328.1 - 0.007 15.9 0.1 0.017 14.7 0.1 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KEZ39328.1 - 0.011 15.5 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family SMC_N PF02463.14 KEZ39329.1 - 1e-26 93.5 0.0 1.7e-26 92.8 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEZ39329.1 - 1.2e-12 48.6 38.2 1.5e-12 48.2 8.9 4.4 3 1 1 4 4 4 1 AAA domain AAA_21 PF13304.1 KEZ39329.1 - 4.9e-08 33.2 0.0 1.8e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ39329.1 - 0.00091 18.7 0.0 0.0029 17.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KEZ39329.1 - 0.0011 19.1 0.0 0.0055 16.9 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KEZ39329.1 - 0.013 14.7 0.0 0.049 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 KEZ39329.1 - 0.036 13.7 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KEZ39329.1 - 0.043 13.9 1.5 0.24 11.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KEZ39329.1 - 0.18 11.9 0.0 0.73 10.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase COG5 PF10392.4 KEZ39329.1 - 0.75 9.7 11.6 5.6 6.9 0.0 4.5 4 0 0 4 4 4 0 Golgi transport complex subunit 5 DUF2680 PF10925.3 KEZ39329.1 - 0.87 9.5 10.1 3.4 7.6 0.2 3.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2680) AAA_15 PF13175.1 KEZ39329.1 - 1.3 7.9 5.3 0.47 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KEZ39329.1 - 1.7 9.4 9.6 0.15 12.9 0.8 3.7 2 2 1 3 3 2 0 AAA domain AAA_10 PF12846.2 KEZ39329.1 - 4.7 6.5 11.3 0.36 10.2 1.7 2.8 2 1 0 2 2 2 0 AAA-like domain BLOC1_2 PF10046.4 KEZ39329.1 - 6.2 7.0 30.2 0.23 11.6 0.1 6.1 4 1 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Reo_sigmaC PF04582.7 KEZ39329.1 - 8.7 5.4 8.1 39 3.2 0.4 3.8 4 1 1 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 KEZ39329.1 - 9.5 6.5 17.5 20 5.4 7.6 4.6 3 2 0 3 3 3 0 ABC transporter ApbA_C PF08546.6 KEZ39330.1 - 7.3e-25 87.3 0.0 1.2e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KEZ39330.1 - 1.1e-18 67.1 0.0 1.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DASH_Hsk3 PF08227.6 KEZ39331.1 - 6.4e-21 74.2 4.9 1.1e-20 73.5 3.4 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like MRP-L28 PF09812.4 KEZ39331.1 - 0.05 13.4 0.1 0.057 13.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 ADIP PF11559.3 KEZ39331.1 - 0.056 13.3 0.7 0.069 13.0 0.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GCV_T PF01571.16 KEZ39331.1 - 0.07 12.4 0.1 0.076 12.3 0.0 1.0 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain Nup54 PF13874.1 KEZ39331.1 - 0.14 11.8 1.4 0.19 11.3 1.0 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DEAD PF00270.24 KEZ39332.1 - 3e-37 127.7 0.1 5e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ39332.1 - 9.7e-24 83.0 0.0 7.5e-23 80.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ39332.1 - 4e-05 23.5 0.1 0.00011 22.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cyclin PF08613.6 KEZ39333.1 - 1.7e-13 51.1 0.2 5.5e-13 49.5 0.0 1.9 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KEZ39333.1 - 0.0019 17.7 0.1 0.0061 16.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain F-box-like PF12937.2 KEZ39334.1 - 0.037 13.7 0.5 0.064 12.9 0.3 1.4 1 0 0 1 1 1 0 F-box-like CorA PF01544.13 KEZ39335.1 - 4.4e-14 52.2 0.1 6.6e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ERCC4 PF02732.10 KEZ39337.1 - 2.3e-25 89.0 0.0 4.8e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain YjeF_N PF03853.10 KEZ39338.1 - 1.8e-23 82.9 0.0 3.4e-23 82.1 0.0 1.4 1 1 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 KEZ39339.1 - 4.4e-25 87.1 0.1 5.7e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.13 KEZ39340.1 - 1.1e-86 290.8 18.0 1.9e-86 290.1 12.5 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KEZ39340.1 - 3.1e-05 22.9 22.1 3.1e-05 22.9 15.3 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SH3_1 PF00018.23 KEZ39342.1 - 1.4e-09 37.1 0.1 2.3e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ39342.1 - 5.2e-07 29.1 0.0 9.8e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEZ39342.1 - 5.2e-07 29.0 0.0 9.5e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DASH_Spc19 PF08287.6 KEZ39343.1 - 6.3e-41 139.5 0.2 8.5e-41 139.1 0.1 1.2 1 0 0 1 1 1 1 Spc19 COG5 PF10392.4 KEZ39343.1 - 0.1 12.5 0.9 20 5.1 0.0 2.6 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Radical_SAM PF04055.16 KEZ39344.1 - 1.6e-13 51.1 0.1 2.4e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Pectate_lyase_3 PF12708.2 KEZ39345.1 - 4e-82 275.6 7.3 1e-67 228.5 0.6 2.7 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KEZ39345.1 - 0.0011 18.4 1.8 0.055 12.9 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Methyltrn_RNA_3 PF02598.12 KEZ39346.1 - 9.4e-79 264.7 0.0 1.2e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Rsm22 PF09243.5 KEZ39347.1 - 1.4e-31 109.5 0.0 5.2e-31 107.6 0.0 1.9 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Thioredoxin PF00085.15 KEZ39347.1 - 3.8e-25 87.5 0.0 6.9e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Methyltransf_23 PF13489.1 KEZ39347.1 - 8.4e-06 25.5 0.0 4.2e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Thioredoxin_8 PF13905.1 KEZ39347.1 - 0.00014 21.9 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEZ39347.1 - 0.00017 21.7 0.1 0.00063 19.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KEZ39347.1 - 0.00074 19.1 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KEZ39347.1 - 0.0061 16.1 0.1 0.043 13.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 KEZ39347.1 - 0.016 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Methyltransf_12 PF08242.7 KEZ39347.1 - 0.016 15.6 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Redoxin PF08534.5 KEZ39347.1 - 0.063 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Redoxin QRPTase_C PF01729.14 KEZ39348.1 - 6.4e-53 178.7 0.0 7.6e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KEZ39348.1 - 1.5e-21 75.9 0.0 5.2e-21 74.2 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 KEZ39348.1 - 0.037 13.5 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase B12-binding PF02310.14 KEZ39348.1 - 0.077 12.8 0.3 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 B12 binding domain FHA PF00498.21 KEZ39349.1 - 2e-16 59.8 0.0 5.3e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain DUF4631 PF15450.1 KEZ39349.1 - 6.1e-05 21.4 5.3 6.1e-05 21.4 3.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4631) GAS PF13851.1 KEZ39349.1 - 0.0021 17.3 13.3 0.027 13.6 2.0 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF4201 PF13870.1 KEZ39349.1 - 0.025 14.0 12.8 0.53 9.6 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Laminin_II PF06009.7 KEZ39349.1 - 0.13 11.9 14.8 0.95 9.2 3.5 2.4 2 0 0 2 2 2 0 Laminin Domain II Mod_r PF07200.8 KEZ39349.1 - 0.21 11.5 13.3 1.5 8.7 1.0 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CENP-Q PF13094.1 KEZ39349.1 - 0.73 9.8 27.4 0.67 9.9 4.1 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Mnd1 PF03962.10 KEZ39349.1 - 0.86 9.2 18.0 0.87 9.2 1.8 2.3 2 0 0 2 2 2 0 Mnd1 family FliJ PF02050.11 KEZ39349.1 - 1 9.3 23.0 1.2 9.2 2.6 3.1 3 1 0 3 3 3 0 Flagellar FliJ protein TBPIP PF07106.8 KEZ39349.1 - 1.5 8.3 10.8 6.2 6.3 2.9 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FH2 PF02181.18 KEZ39349.1 - 3.8 6.2 8.4 7.4 5.3 1.0 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain EAP30 PF04157.11 KEZ39349.1 - 5.3 6.1 14.2 0.28 10.2 3.6 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family COG2 PF06148.6 KEZ39349.1 - 6.6 6.6 12.2 2.1 8.1 0.8 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Romo1 PF10247.4 KEZ39350.1 - 2.7e-25 88.3 12.4 3.9e-25 87.8 8.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.1 KEZ39350.1 - 0.016 14.7 0.9 0.03 13.8 0.7 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Tim17 PF02466.14 KEZ39350.1 - 0.027 14.5 3.9 0.036 14.1 2.7 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 KEZ39350.1 - 0.19 11.3 4.1 0.5 10.0 2.8 1.7 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SIR2 PF02146.12 KEZ39351.1 - 2.6e-54 183.6 0.0 3.7e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family GMC_oxred_N PF00732.14 KEZ39352.1 - 8.3e-45 153.1 0.0 1.1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39352.1 - 6.9e-24 84.7 0.0 1.5e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ39352.1 - 9.3e-06 24.7 0.3 0.00021 20.2 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KEZ39352.1 - 0.0052 15.9 0.1 0.009 15.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KEZ39352.1 - 0.0097 15.9 0.1 0.035 14.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ39352.1 - 0.019 13.8 0.1 0.057 12.3 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ39352.1 - 0.021 14.8 0.0 0.093 12.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KEZ39352.1 - 0.022 14.7 0.1 0.21 11.6 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 KEZ39352.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Carb_anhydrase PF00194.16 KEZ39353.1 - 1.4e-22 79.9 0.0 2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF619 PF04768.8 KEZ39354.1 - 1.6e-36 125.2 0.1 3.8e-36 124.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KEZ39354.1 - 6.4e-29 100.7 0.0 1.9e-28 99.1 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KEZ39354.1 - 7.6e-23 81.2 0.0 1.5e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KEZ39354.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 KEZ39355.1 - 2.9e-34 116.5 1.4 3.3e-34 116.3 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2976 PF11190.3 KEZ39355.1 - 0.089 12.3 0.6 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Glyco_hydro_76 PF03663.9 KEZ39356.1 - 1.5e-149 498.4 22.7 1.8e-149 498.1 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.17 KEZ39357.1 - 1.3e-34 119.5 0.0 1.6e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_U44 PF04533.8 KEZ39357.1 - 0.012 14.9 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Herpes virus U44 protein Ribosomal_S14 PF00253.16 KEZ39358.1 - 9.5e-20 69.7 2.4 5.6e-19 67.2 0.5 2.1 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e zf-DHHC PF01529.15 KEZ39359.1 - 5.5e-37 126.8 2.0 1.6e-36 125.3 1.4 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 KEZ39359.1 - 6.4e-05 22.5 2.7 0.00024 20.6 0.1 2.1 2 0 0 2 2 2 1 Yip1 domain DUF4366 PF14283.1 KEZ39360.1 - 0.048 13.0 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TYW3 PF02676.9 KEZ39361.1 - 8e-64 214.5 0.0 9.8e-64 214.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.6 KEZ39362.1 - 1.3e-33 115.9 0.9 1.5e-33 115.7 0.6 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lebercilin PF15619.1 KEZ39362.1 - 0.00026 20.4 7.8 0.00033 20.1 5.4 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease PAP_central PF04928.12 KEZ39362.1 - 0.28 9.9 1.3 0.36 9.5 0.9 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain HrpA_pilin PF09589.5 KEZ39362.1 - 0.39 11.1 3.1 5.4 7.4 2.1 2.1 1 1 0 1 1 1 0 HrpA pilus formation protein FliJ PF02050.11 KEZ39362.1 - 6.2 6.8 9.0 0.78 9.8 2.2 2.3 3 0 0 3 3 3 0 Flagellar FliJ protein APH PF01636.18 KEZ39363.1 - 6.3e-15 55.5 0.0 2e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEZ39363.1 - 0.0033 16.6 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 KEZ39363.1 - 0.0043 15.7 0.0 0.018 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Pkinase PF00069.20 KEZ39363.1 - 0.016 14.3 0.0 0.049 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein kinase domain HEAT_EZ PF13513.1 KEZ39364.1 - 1.2e-11 44.6 10.3 6.5e-06 26.4 0.0 8.7 8 2 3 11 11 11 2 HEAT-like repeat HEAT PF02985.17 KEZ39364.1 - 1.8e-11 43.0 14.2 0.16 12.0 0.0 10.1 12 1 1 13 13 13 4 HEAT repeat HEAT_2 PF13646.1 KEZ39364.1 - 9.6e-11 41.8 16.2 0.0084 16.3 0.0 7.6 3 1 7 10 10 10 8 HEAT repeats IBN_N PF03810.14 KEZ39364.1 - 8e-09 35.2 7.5 1.2e-08 34.6 0.7 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain RIX1 PF08167.7 KEZ39364.1 - 1.9e-06 27.6 1.0 0.069 12.8 0.2 5.5 2 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 KEZ39364.1 - 0.0016 17.8 5.9 5.5 6.2 0.1 5.8 3 2 5 8 8 8 2 CLASP N terminal DUF1548 PF07579.6 KEZ39364.1 - 0.11 12.6 0.7 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) Lipase_GDSL_2 PF13472.1 KEZ39367.1 - 2.2e-08 34.4 1.1 2.2e-08 34.4 0.8 1.9 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ39367.1 - 9e-08 32.2 8.5 2.8e-07 30.5 5.9 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KEZ39367.1 - 0.0029 17.3 0.1 0.37 10.5 0.0 2.2 1 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family zf-C2H2 PF00096.21 KEZ39368.1 - 3.6e-07 30.1 17.7 0.00041 20.5 1.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEZ39368.1 - 1.7e-06 28.0 1.7 1.7e-06 28.0 1.2 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEZ39368.1 - 7e-05 22.8 10.7 0.01 16.0 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KEZ39368.1 - 0.041 14.0 1.5 0.041 14.0 1.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEZ39368.1 - 0.072 13.2 0.7 0.072 13.2 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Suf PF05843.9 KEZ39368.1 - 2.6 7.7 11.1 3.7 7.1 7.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-BED PF02892.10 KEZ39368.1 - 4.3 7.1 7.5 25 4.7 1.1 2.5 1 1 1 2 2 2 0 BED zinc finger Pkinase PF00069.20 KEZ39369.1 - 8.1e-57 192.3 0.0 1.2e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39369.1 - 3.3e-35 121.4 0.0 4.8e-34 117.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39369.1 - 7.1e-05 21.8 0.0 0.00019 20.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like BTB PF00651.26 KEZ39370.1 - 2.1e-25 88.8 1.8 1.1e-12 47.8 1.2 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank PF00023.25 KEZ39370.1 - 1.6e-10 40.2 0.2 1.9e-05 24.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KEZ39370.1 - 5e-10 39.5 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ39370.1 - 8.5e-10 38.8 0.0 2.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ39370.1 - 6.6e-07 28.9 0.1 0.0036 17.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEZ39370.1 - 1.9e-06 27.9 0.0 1e-05 25.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DNA_gyraseB_C PF00986.16 KEZ39370.1 - 0.037 13.7 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Shadoo PF14999.1 KEZ39370.1 - 2.9 7.7 8.2 5.5 6.8 5.7 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SCO1-SenC PF02630.9 KEZ39371.1 - 4.3e-60 202.2 0.0 5.6e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KEZ39371.1 - 7.4e-05 22.4 0.0 0.00016 21.3 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEZ39371.1 - 0.009 15.5 0.0 0.1 12.1 0.0 2.1 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 KEZ39371.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Hydrolase_6 PF13344.1 KEZ39372.1 - 6.1e-26 90.2 0.0 1e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ39372.1 - 1.6e-15 56.5 0.0 8.1e-15 54.2 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KEZ39372.1 - 0.00034 20.8 0.1 0.31 11.2 0.0 3.9 2 2 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEZ39372.1 - 0.0049 17.2 0.1 7.7 6.8 0.0 3.5 2 1 2 4 4 4 2 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.15 KEZ39373.1 - 4.6e-51 173.3 0.0 5.6e-50 169.8 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KEZ39373.1 - 3.3e-19 68.0 0.0 7.5e-19 66.9 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus Rad21_Rec8_N PF04825.8 KEZ39373.1 - 1.1e-18 67.2 0.0 2.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KEZ39373.1 - 2.3e-06 26.6 0.0 6.9e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein GDI PF00996.13 KEZ39374.1 - 1.6e-39 135.5 0.0 2.1e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor MoaE PF02391.12 KEZ39375.1 - 3.1e-30 104.3 0.1 6e-30 103.4 0.1 1.5 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.18 KEZ39376.1 - 7.3e-12 44.8 1.9 1.6e-11 43.8 1.3 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KEZ39376.1 - 4.4e-06 26.4 1.5 1.1e-05 25.1 0.8 1.9 1 1 0 1 1 1 1 DExH-box splicing factor binding site RRM_6 PF14259.1 KEZ39376.1 - 5.5e-06 26.2 0.0 0.033 14.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 KEZ39376.1 - 0.00054 19.2 2.2 0.00054 19.2 1.5 1.6 2 0 0 2 2 2 1 RED-like protein N-terminal region RRM_1 PF00076.17 KEZ39376.1 - 0.0028 17.2 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.2 KEZ39376.1 - 0.026 14.6 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SET PF00856.23 KEZ39377.1 - 1.6e-12 48.0 0.2 1.6e-11 44.7 0.1 2.2 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 KEZ39377.1 - 0.033 14.1 0.2 0.17 11.8 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat ATP-synt_C PF00137.16 KEZ39379.1 - 1.2e-26 92.3 27.9 2e-15 56.3 4.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C UPF0220 PF05255.6 KEZ39379.1 - 0.11 11.7 1.0 0.2 10.9 0.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF4199 PF13858.1 KEZ39379.1 - 8.7 6.2 12.0 0.66 9.8 0.5 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF4199) CNH PF00780.17 KEZ39380.1 - 7.8e-79 264.9 0.0 2.6e-78 263.2 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 KEZ39380.1 - 3.3e-44 150.0 0.0 3.3e-44 150.0 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 KEZ39380.1 - 4.8e-39 134.0 0.1 9.1e-39 133.1 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KEZ39380.1 - 1.6e-15 56.5 0.0 3.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 KEZ39380.1 - 0.0086 16.2 0.0 0.06 13.5 0.0 2.4 1 1 0 1 1 1 1 PH domain PAP2_3 PF14378.1 KEZ39380.1 - 0.23 10.9 0.0 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily Thioredox_DsbH PF03190.10 KEZ39381.1 - 5e-57 192.1 0.0 8.2e-57 191.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KEZ39381.1 - 1.2e-07 31.6 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEZ39381.1 - 0.021 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Glyco_hydro_76 PF03663.9 KEZ39381.1 - 0.12 11.7 2.3 1 8.6 0.5 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 DLIC PF05783.6 KEZ39382.1 - 4e-34 118.0 0.0 2.9e-32 111.9 0.0 2.3 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 KEZ39383.1 - 1.1e-13 50.5 0.0 2.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ39383.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ39383.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KEZ39384.1 - 6.1e-11 41.7 3.4 0.00061 19.5 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat IKI3 PF04762.7 KEZ39384.1 - 5.6e-05 21.1 0.0 0.0002 19.3 0.0 1.8 2 1 1 3 3 3 1 IKI3 family Nbas_N PF15492.1 KEZ39384.1 - 0.15 11.1 0.0 1.7 7.6 0.0 2.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 KEZ39385.1 - 2.2e-108 361.5 0.1 4.8e-108 360.4 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KEZ39385.1 - 0.0004 20.3 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ39385.1 - 0.0082 15.3 0.3 0.03 13.4 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEZ39385.1 - 0.0094 15.7 3.3 1.3 8.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_17 PF13207.1 KEZ39385.1 - 0.014 16.1 3.2 0.066 14.0 0.1 2.8 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 KEZ39385.1 - 0.016 15.3 0.1 0.06 13.4 0.0 2.0 2 2 0 2 2 2 0 AAA domain Miro PF08477.8 KEZ39385.1 - 0.021 15.3 0.3 0.068 13.6 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 KEZ39385.1 - 0.027 13.8 0.1 0.094 12.1 0.1 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEZ39385.1 - 0.073 12.9 0.2 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KEZ39385.1 - 0.11 11.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family V_ATPase_I PF01496.14 KEZ39385.1 - 1.5 6.5 3.7 2.2 6.0 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bax1-I PF01027.15 KEZ39386.1 - 3.3e-48 164.0 28.3 3.9e-48 163.7 19.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF417 PF04224.7 KEZ39386.1 - 0.033 13.5 0.4 0.033 13.5 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function, DUF417 Orbi_NS3 PF01616.11 KEZ39386.1 - 0.062 12.2 1.4 0.5 9.3 0.1 2.2 2 0 0 2 2 2 0 Orbivirus NS3 DsbD_2 PF13386.1 KEZ39386.1 - 0.12 12.0 10.7 0.21 11.2 7.4 1.4 1 1 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Pol_alpha_B_N PF08418.5 KEZ39387.1 - 0.013 15.0 7.1 0.21 11.0 0.7 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Herpes_capsid PF06112.6 KEZ39387.1 - 3.1 7.8 17.5 3.2 7.8 1.3 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein TRAM_LAG1_CLN8 PF03798.11 KEZ39388.1 - 4.9e-47 160.0 17.0 8.6e-47 159.2 11.8 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KEZ39388.1 - 2.9e-19 68.3 0.1 1.2e-18 66.3 0.1 2.1 1 0 0 1 1 1 1 TRAM1-like protein Gly_transf_sug PF04488.10 KEZ39389.1 - 8.1e-14 51.8 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Cu_amine_oxid PF01179.15 KEZ39390.1 - 1.9e-134 448.5 0.0 4.1e-134 447.3 0.0 1.5 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KEZ39390.1 - 5.3e-08 32.8 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KEZ39390.1 - 0.00038 20.4 0.0 0.00079 19.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain NUDIX PF00293.23 KEZ39392.1 - 2.6e-06 27.1 0.0 4.6e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain PP-binding PF00550.20 KEZ39392.1 - 0.089 13.0 0.1 26 5.1 0.0 2.6 2 0 0 2 2 2 0 Phosphopantetheine attachment site NUDIX PF00293.23 KEZ39393.1 - 1.4e-16 60.3 0.0 2.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CBFD_NFYB_HMF PF00808.18 KEZ39394.1 - 6.2e-17 61.4 0.2 6.2e-17 61.4 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEZ39394.1 - 2.1e-05 24.5 0.1 4.7e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Decorin_bind PF02352.10 KEZ39394.1 - 0.07 13.1 0.2 0.19 11.7 0.1 1.7 1 1 0 1 1 1 0 Decorin binding protein Bromo_TP PF07524.8 KEZ39394.1 - 0.077 12.7 0.4 0.19 11.5 0.0 1.8 2 1 1 3 3 3 0 Bromodomain associated Histone_HNS PF00816.16 KEZ39394.1 - 2.3 8.7 5.0 7.4 7.1 1.2 2.2 1 1 1 2 2 2 0 H-NS histone family adh_short PF00106.20 KEZ39395.1 - 3.7e-17 62.7 2.8 2e-13 50.5 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ39395.1 - 8.7e-08 32.2 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ39395.1 - 0.14 11.8 1.1 0.56 9.8 0.1 1.9 1 1 1 2 2 2 0 KR domain APH PF01636.18 KEZ39396.1 - 2.8e-09 37.0 0.1 5.7e-08 32.7 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family HNH_2 PF13391.1 KEZ39396.1 - 3.4e-07 29.9 0.0 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease PPDK_N PF01326.14 KEZ39396.1 - 0.14 11.1 0.2 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain COX16 PF14138.1 KEZ39397.1 - 2.4e-28 98.1 0.2 3.2e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.6 KEZ39397.1 - 0.016 15.6 0.1 0.053 13.9 0.0 1.8 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Ribosomal_L24e PF01246.15 KEZ39397.1 - 0.22 11.3 1.6 0.4 10.5 1.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L24e Amidase PF01425.16 KEZ39398.1 - 2.2e-99 333.3 0.1 3.8e-99 332.5 0.1 1.3 1 1 0 1 1 1 1 Amidase Metallophos PF00149.23 KEZ39399.1 - 3.2e-07 29.9 2.4 7.1e-07 28.8 1.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PCI PF01399.22 KEZ39400.1 - 1.9e-22 79.5 0.0 8.1e-22 77.5 0.0 2.1 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 KEZ39400.1 - 8e-06 25.3 2.8 0.0076 15.5 0.3 2.4 2 0 0 2 2 2 2 Putative aspartate racemase FSH1 PF03959.8 KEZ39401.1 - 3e-60 203.2 0.0 3.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KEZ39401.1 - 1.7e-07 31.3 3.0 9e-06 25.7 2.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ39401.1 - 2.7e-05 23.9 0.1 4.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KEZ39401.1 - 0.0015 17.8 0.1 0.083 12.1 0.2 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase DLH PF01738.13 KEZ39401.1 - 0.002 17.4 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KEZ39401.1 - 0.023 14.1 0.1 4 6.8 0.4 3.0 3 1 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KEZ39401.1 - 0.05 13.8 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 KEZ39401.1 - 0.067 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2048 PF09752.4 KEZ39401.1 - 0.11 11.3 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) AXE1 PF05448.7 KEZ39401.1 - 0.2 10.0 0.2 0.31 9.5 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) NIPSNAP PF07978.8 KEZ39402.1 - 2.9e-39 133.1 0.5 5e-28 97.0 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.4 KEZ39403.1 - 4.8e-54 183.3 0.0 5.5e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 KEZ39404.1 - 1.3e-28 99.5 2.3 1.7e-28 99.0 1.6 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KEZ39404.1 - 4.5e-16 58.1 0.8 7.3e-16 57.5 0.5 1.3 1 0 0 1 1 1 1 Alba DUF3614 PF12267.3 KEZ39404.1 - 0.023 14.9 1.6 0.028 14.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) TRSP PF12500.3 KEZ39404.1 - 0.079 12.4 0.1 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 TRSP domain C terminus to PRTase_2 ketoacyl-synt PF00109.21 KEZ39405.1 - 1.1e-71 241.3 0.0 3.6e-71 239.6 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEZ39405.1 - 1.2e-60 205.5 0.0 2e-60 204.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEZ39405.1 - 1.6e-59 200.5 2.2 5.5e-59 198.8 1.5 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEZ39405.1 - 8.7e-51 172.1 5.6 2.9e-50 170.4 2.1 3.2 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 KEZ39405.1 - 6e-44 150.3 0.0 1.2e-43 149.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEZ39405.1 - 1.9e-41 140.6 0.2 8.2e-41 138.5 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEZ39405.1 - 6.2e-17 61.3 0.4 1.7e-15 56.7 0.1 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ39405.1 - 7.9e-12 46.1 0.0 3.8e-11 43.9 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ39405.1 - 2.3e-08 33.7 0.0 6.1e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEZ39405.1 - 0.00025 21.2 0.2 0.0039 17.4 0.2 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KEZ39405.1 - 0.0014 17.7 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain FSH1 PF03959.8 KEZ39406.1 - 1.1e-25 90.3 0.0 4.3e-25 88.4 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ABC_membrane PF00664.18 KEZ39407.1 - 3e-68 230.2 25.2 9.1e-41 140.0 4.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ39407.1 - 8.6e-65 217.1 0.0 1.1e-32 113.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ39407.1 - 2.5e-14 53.0 3.3 0.00078 18.7 0.3 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ39407.1 - 4.1e-14 53.2 0.2 0.0005 20.1 0.0 4.2 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KEZ39407.1 - 1.9e-07 30.0 1.1 0.02 13.4 0.0 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KEZ39407.1 - 3.3e-07 29.7 3.0 0.00038 19.9 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KEZ39407.1 - 3.4e-07 30.4 2.2 0.096 12.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEZ39407.1 - 6.1e-07 30.2 0.7 0.081 13.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ39407.1 - 8e-07 29.2 1.1 0.015 15.3 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KEZ39407.1 - 1.4e-06 27.6 0.0 0.053 12.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEZ39407.1 - 9.9e-05 21.8 3.0 0.16 11.3 0.0 3.4 5 0 0 5 5 4 2 AAA domain SbcCD_C PF13558.1 KEZ39407.1 - 0.00022 21.0 0.7 0.69 9.8 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KEZ39407.1 - 0.0008 19.7 2.4 0.14 12.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KEZ39407.1 - 0.0014 18.1 3.3 0.19 11.2 0.3 3.3 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 KEZ39407.1 - 0.0019 17.7 5.0 0.2 11.0 0.0 4.6 5 0 0 5 5 5 1 AAA-like domain AAA_18 PF13238.1 KEZ39407.1 - 0.0027 17.9 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KEZ39407.1 - 0.003 17.3 0.5 0.62 9.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 KEZ39407.1 - 0.0045 16.5 8.6 0.24 10.9 0.4 4.1 4 1 0 4 4 3 2 AAA domain MobB PF03205.9 KEZ39407.1 - 0.0053 16.4 0.6 2.6 7.7 0.0 3.4 4 0 0 4 4 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KEZ39407.1 - 0.019 14.8 0.4 2.1 8.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEZ39407.1 - 0.021 14.7 0.1 22 4.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.9 KEZ39407.1 - 0.021 14.5 0.0 8.1 6.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KEZ39407.1 - 0.032 13.8 0.2 5.1 6.6 0.0 3.1 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.12 KEZ39407.1 - 0.039 13.4 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KEZ39407.1 - 0.05 13.5 0.2 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 KEZ39407.1 - 0.08 12.4 0.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 KEZ39407.1 - 0.094 11.7 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 KEZ39407.1 - 0.1 13.0 0.4 9.9 6.6 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein DUF3237 PF11578.3 KEZ39408.1 - 1.1e-13 50.8 0.0 1.9e-13 49.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3237) CAP PF00188.21 KEZ39409.1 - 4.6e-23 82.0 3.1 6.1e-23 81.6 2.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TFIIA PF03153.8 KEZ39409.1 - 2.9 7.6 5.5 3.4 7.4 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KEZ39409.1 - 4.5 5.3 11.6 5.3 5.1 8.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Trypan_PARP PF05887.6 KEZ39409.1 - 6.7 6.5 35.1 21 4.9 24.3 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CHCH PF06747.8 KEZ39410.1 - 4.3e-06 26.4 14.4 0.0001 22.0 3.3 2.5 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KEZ39410.1 - 0.00078 19.1 9.3 0.23 11.2 1.9 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KEZ39410.1 - 2.1 8.4 7.5 6.7 6.8 3.5 2.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Nup54 PF13874.1 KEZ39411.1 - 1.7e-43 147.6 0.2 1.7e-43 147.6 0.1 2.8 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 DivIVA PF05103.8 KEZ39411.1 - 0.008 16.2 2.9 0.008 16.2 2.0 2.7 3 0 0 3 3 3 1 DivIVA protein Nucleoporin_FG PF13634.1 KEZ39411.1 - 0.042 14.0 7.7 0.074 13.2 5.3 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region YliH PF10799.3 KEZ39411.1 - 0.056 13.1 0.2 0.16 11.6 0.0 1.9 1 1 1 2 2 2 0 Biofilm formation protein (YliH/bssR) DUF342 PF03961.8 KEZ39411.1 - 0.94 7.8 5.0 1.4 7.2 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 KEZ39411.1 - 1.6 9.0 6.3 6.6 7.0 0.0 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein bZIP_2 PF07716.10 KEZ39411.1 - 4.3 7.2 7.7 19 5.1 1.0 3.7 4 0 0 4 4 4 0 Basic region leucine zipper GDC-P PF02347.11 KEZ39412.1 - 3.2e-170 566.4 0.1 1.2e-155 518.4 0.0 2.6 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 KEZ39412.1 - 2.3e-10 39.7 0.0 4.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEZ39412.1 - 1.5e-06 27.5 0.0 3.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KEZ39412.1 - 0.0017 16.7 0.0 0.0063 14.8 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEZ39412.1 - 0.041 12.9 0.0 0.094 11.7 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SUR7 PF06687.7 KEZ39414.1 - 1e-31 110.1 8.8 1.4e-31 109.7 6.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KEZ39414.1 - 0.00033 20.3 12.5 0.00033 20.3 8.7 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 KEZ39414.1 - 0.0045 16.2 2.8 0.0076 15.5 1.9 1.5 1 0 0 1 1 1 1 Clc-like Amastin PF07344.6 KEZ39414.1 - 0.072 12.6 9.3 0.18 11.4 6.5 1.6 1 0 0 1 1 1 0 Amastin surface glycoprotein Fig1 PF12351.3 KEZ39414.1 - 5.6 6.8 17.4 0.45 10.3 5.6 2.2 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Peptidase_C65 PF10275.4 KEZ39415.1 - 5.7e-64 215.7 0.0 9e-64 215.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 KEZ39416.1 - 6.8e-19 68.1 1.3 2e-18 66.6 0.1 2.4 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 KEZ39416.1 - 1.3e-07 31.4 0.2 5.1e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 KEZ39416.1 - 0.0068 16.0 0.0 0.023 14.3 0.0 1.9 2 0 0 2 2 2 1 FeoC like transcriptional regulator AAA_10 PF12846.2 KEZ39416.1 - 0.056 12.8 0.5 12 5.2 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain Ipi1_N PF12333.3 KEZ39416.1 - 0.1 12.5 1.5 0.24 11.4 0.1 2.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Syntaxin PF00804.20 KEZ39416.1 - 0.35 11.0 5.1 6.9 6.8 0.0 3.1 2 1 0 2 2 2 0 Syntaxin CWC25 PF12542.3 KEZ39417.1 - 5.9e-26 90.7 3.2 5.9e-26 90.7 2.2 4.0 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KEZ39417.1 - 1.5e-14 53.7 4.9 1.5e-14 53.7 3.4 3.8 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 KEZ39417.1 - 0.16 11.4 0.1 0.47 9.9 0.1 1.8 1 0 0 1 1 1 0 RNA dependent RNA polymerase Ras PF00071.17 KEZ39418.1 - 3.5e-52 176.0 0.0 4.6e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ39418.1 - 7.8e-14 52.1 0.0 1.2e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ39418.1 - 1.9e-06 27.2 0.0 3.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ39418.1 - 0.061 12.4 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glyco_hydro_16 PF00722.16 KEZ39419.1 - 1e-40 138.9 2.3 2.1e-40 137.9 1.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Citrate_synt PF00285.16 KEZ39420.1 - 2e-101 339.3 0.0 2.5e-101 338.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_98M PF08306.6 KEZ39420.1 - 0.076 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 ICL PF00463.16 KEZ39421.1 - 3.4e-199 662.4 0.7 3.9e-199 662.2 0.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KEZ39421.1 - 5.7e-11 42.0 0.0 2.8e-10 39.8 0.0 1.9 1 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase FliO PF04347.8 KEZ39421.1 - 0.045 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO adh_short PF00106.20 KEZ39422.1 - 1.2e-24 87.0 1.9 1.7e-24 86.6 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ39422.1 - 1.5e-18 67.4 0.0 1.8e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ39422.1 - 2.5e-07 30.5 0.8 4.6e-07 29.6 0.5 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KEZ39422.1 - 0.0011 18.6 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KEZ39422.1 - 0.028 14.2 0.2 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_18 PF12847.2 KEZ39422.1 - 0.029 14.9 0.0 0.064 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39422.1 - 0.037 14.4 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 KEZ39422.1 - 0.04 13.7 4.5 0.71 9.7 0.9 3.1 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KEZ39422.1 - 0.089 11.8 0.0 0.24 10.4 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KEZ39422.1 - 0.12 11.8 0.1 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1625 PF07787.7 KEZ39424.1 - 0.43 9.7 1.6 0.68 9.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Pkinase PF00069.20 KEZ39425.1 - 9.1e-12 44.6 0.0 1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Gln-synt_C PF00120.19 KEZ39426.1 - 5.4e-59 199.4 0.0 6.8e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Pkinase PF00069.20 KEZ39427.1 - 2.2e-50 171.2 0.0 9.8e-48 162.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39427.1 - 6.1e-30 104.1 0.0 6e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39427.1 - 1.8e-05 23.8 0.0 2.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KEZ39427.1 - 0.0033 16.3 0.1 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KEZ39427.1 - 0.16 10.7 0.1 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mem_trans PF03547.13 KEZ39428.1 - 6.6e-53 179.3 0.0 1e-52 178.7 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Nse5 PF08691.5 KEZ39428.1 - 0.1 11.1 0.6 0.16 10.4 0.4 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Pyridox_oxidase PF01243.15 KEZ39429.1 - 5e-13 48.8 0.0 1.8e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 KEZ39429.1 - 0.0026 15.8 0.1 0.0031 15.6 0.1 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Pyridox_ox_2 PF12900.2 KEZ39429.1 - 0.0032 17.2 0.0 0.085 12.6 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.12 KEZ39430.1 - 6.1e-72 241.3 0.0 9.2e-72 240.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KEZ39430.1 - 5.6e-36 122.7 0.0 1.1e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KEZ39430.1 - 6e-35 119.6 0.0 1.3e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KEZ39430.1 - 3.9e-19 69.0 0.1 2.1e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KEZ39430.1 - 1.3e-16 59.9 2.1 3.9e-16 58.4 1.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KEZ39430.1 - 5.5e-15 54.9 0.0 9.3e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KEZ39430.1 - 4.2e-08 32.7 0.0 0.006 16.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KEZ39430.1 - 7.4e-08 32.0 0.0 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEZ39430.1 - 1.1e-05 24.8 0.0 2.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KEZ39430.1 - 0.00013 22.2 0.1 0.41 10.9 0.0 3.1 3 0 0 3 3 2 2 HlyD family secretion protein HlyD PF00529.15 KEZ39430.1 - 0.00013 21.4 0.1 0.1 11.8 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 KEZ39430.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 KEZ39430.1 - 0.0045 16.1 0.1 0.55 9.3 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein RimK PF08443.6 KEZ39430.1 - 0.01 15.3 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GCV_H PF01597.14 KEZ39430.1 - 0.068 12.8 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein TP_methylase PF00590.15 KEZ39431.1 - 3.5e-42 144.4 0.1 8e-42 143.3 0.0 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KEZ39431.1 - 1.1e-14 54.5 0.0 2.3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KEZ39431.1 - 1.1e-07 30.9 0.0 8.9e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KEZ39431.1 - 2.8e-06 26.2 0.0 6.2e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central RRM_1 PF00076.17 KEZ39432.1 - 1.6e-15 56.4 0.0 2.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ39432.1 - 8.8e-12 44.8 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ39432.1 - 3.4e-07 30.0 0.0 6.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ39432.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_trans_2_3 PF13632.1 KEZ39433.1 - 1.1e-48 165.4 2.6 2.6e-48 164.2 1.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ39433.1 - 2.2e-07 30.9 0.1 5.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEZ39433.1 - 6.4e-06 25.9 0.0 1.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KEZ39433.1 - 0.00017 20.9 0.0 0.00036 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 KEZ39434.1 - 1.3e-19 70.2 0.7 2.2e-19 69.4 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.2 KEZ39434.1 - 0.097 12.4 0.1 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain ABC_tran PF00005.22 KEZ39435.1 - 1.1e-47 161.8 0.0 7.9e-25 87.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KEZ39435.1 - 2.1e-17 64.0 0.1 2.5e-07 30.9 0.0 3.4 2 1 1 3 3 3 3 AAA domain SMC_N PF02463.14 KEZ39435.1 - 2e-13 50.0 0.0 0.00015 21.0 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEZ39435.1 - 3.5e-09 37.3 0.3 2.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEZ39435.1 - 2.7e-07 30.0 0.3 0.01 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ39435.1 - 2.3e-06 28.4 0.0 0.033 14.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KEZ39435.1 - 3e-06 27.1 0.0 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ39435.1 - 4e-06 26.1 0.0 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 KEZ39435.1 - 4.2e-06 26.0 0.0 0.16 11.0 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain SbcCD_C PF13558.1 KEZ39435.1 - 8.5e-06 25.6 0.0 0.083 12.8 0.0 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KEZ39435.1 - 1.1e-05 25.6 0.1 0.088 12.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain Chromo PF00385.19 KEZ39435.1 - 1.4e-05 24.6 0.1 3.2e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_10 PF12846.2 KEZ39435.1 - 0.00013 21.4 0.0 1.3 8.3 0.1 3.5 4 1 0 4 4 4 2 AAA-like domain Miro PF08477.8 KEZ39435.1 - 0.00018 22.0 0.0 0.42 11.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 KEZ39435.1 - 0.00028 20.7 0.2 0.3 10.8 0.0 3.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 MobB PF03205.9 KEZ39435.1 - 0.00029 20.5 0.0 0.97 9.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEZ39435.1 - 0.00051 20.1 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 KEZ39435.1 - 0.00077 19.6 0.0 1.2 9.3 0.0 3.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KEZ39435.1 - 0.00084 19.3 0.0 0.08 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEZ39435.1 - 0.0015 18.4 0.0 2.3 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEZ39435.1 - 0.0017 18.6 0.0 0.47 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEZ39435.1 - 0.003 17.2 0.0 0.48 10.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 KEZ39435.1 - 0.004 15.9 0.3 1.2 7.8 0.0 2.4 2 0 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 KEZ39435.1 - 0.004 16.9 0.0 1 9.1 0.0 3.0 2 1 0 2 2 2 1 Dynamin family AAA_30 PF13604.1 KEZ39435.1 - 0.0081 15.7 0.0 2.8 7.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KEZ39435.1 - 0.0089 15.9 0.0 5.3 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEZ39435.1 - 0.01 15.5 0.0 0.51 9.9 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase PduV-EutP PF10662.4 KEZ39435.1 - 0.017 14.6 0.0 7.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 KEZ39435.1 - 0.02 13.3 0.0 1.8 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEZ39435.1 - 0.021 13.9 0.1 8.4 5.4 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 KEZ39435.1 - 0.025 14.5 1.5 7.7 6.4 0.0 3.8 5 0 0 5 5 3 0 AAA ATPase domain AAA_25 PF13481.1 KEZ39435.1 - 0.04 13.3 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.15 KEZ39435.1 - 0.046 12.0 0.1 0.38 9.0 0.1 2.0 2 0 0 2 2 2 0 Adaptin N terminal region DUF815 PF05673.8 KEZ39435.1 - 0.047 12.6 0.0 5.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MutS_V PF00488.16 KEZ39435.1 - 0.13 11.7 0.1 9.3 5.5 0.0 2.3 2 0 0 2 2 2 0 MutS domain V DUF3584 PF12128.3 KEZ39435.1 - 0.14 9.4 0.7 3.5 4.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HEAT_2 PF13646.1 KEZ39435.1 - 0.17 12.1 5.0 0.7 10.2 0.1 3.4 1 1 3 4 4 4 0 HEAT repeats HET PF06985.6 KEZ39436.1 - 5.7e-25 88.1 0.0 9.7e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRM_DME PF15628.1 KEZ39436.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RRM in Demeter CVNH PF08881.5 KEZ39437.1 - 4.8e-08 33.1 0.7 4.4e-05 23.6 0.1 2.2 1 1 1 2 2 2 2 CVNH domain tRNA_SAD PF07973.9 KEZ39437.1 - 0.055 13.3 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonyl and Alanyl tRNA synthetase second additional domain Dsh_C PF12316.3 KEZ39438.1 - 0.00052 20.1 0.7 0.00073 19.7 0.5 1.3 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal Reo_sigmaC PF04582.7 KEZ39439.1 - 9.1e-15 54.6 39.1 1.2e-07 31.2 3.1 5.0 3 2 3 6 6 6 6 Reovirus sigma C capsid protein IncA PF04156.9 KEZ39439.1 - 2.8e-11 43.3 117.0 1.2e-05 24.9 3.7 7.2 1 1 5 6 6 5 5 IncA protein Myosin_tail_1 PF01576.14 KEZ39439.1 - 4.2e-11 41.3 130.7 4e-06 24.8 7.4 3.1 2 1 1 3 3 3 2 Myosin tail TMF_DNA_bd PF12329.3 KEZ39439.1 - 9e-09 35.0 132.2 0.0035 17.1 1.6 13.6 6 3 5 13 13 12 7 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 KEZ39439.1 - 5.8e-06 25.2 34.7 1.7e-05 23.6 5.0 6.1 2 1 5 7 7 7 4 Spc7 kinetochore protein ATG16 PF08614.6 KEZ39439.1 - 5.9e-06 26.2 4.3 5.9e-06 26.2 3.0 8.6 2 2 5 7 7 7 2 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KEZ39439.1 - 0.00031 19.3 80.1 0.0012 17.4 14.2 4.2 1 1 3 4 4 4 1 AAA domain GAS PF13851.1 KEZ39439.1 - 0.001 18.3 103.5 0.013 14.6 10.5 7.0 2 2 4 6 6 6 4 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.6 KEZ39439.1 - 0.0019 16.5 9.6 0.0019 16.5 6.7 4.2 2 1 2 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 PF12718.2 KEZ39439.1 - 0.0025 17.6 11.7 0.0025 17.6 8.1 6.8 2 1 6 8 8 5 2 Tropomyosin like CCDC144C PF14915.1 KEZ39439.1 - 0.0029 16.5 22.0 0.0029 16.5 15.3 5.0 1 1 3 4 4 3 1 CCDC144C protein coiled-coil region DUF3552 PF12072.3 KEZ39439.1 - 0.003 16.8 12.0 0.003 16.8 8.3 7.2 1 1 6 7 7 4 2 Domain of unknown function (DUF3552) TMF_TATA_bd PF12325.3 KEZ39439.1 - 0.0031 17.2 4.1 0.0031 17.2 2.8 9.8 4 3 5 9 9 9 2 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 KEZ39439.1 - 0.0038 17.0 2.2 0.0038 17.0 1.5 7.7 4 3 2 7 7 7 3 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 KEZ39439.1 - 0.0041 16.9 134.6 0.11 12.4 8.9 7.7 2 2 5 7 7 7 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 KEZ39439.1 - 0.0056 15.9 1.6 0.0056 15.9 1.1 8.8 2 2 7 9 9 9 2 Protein of unknown function (DUF3450) ADIP PF11559.3 KEZ39439.1 - 0.0059 16.5 0.2 0.0059 16.5 0.1 9.4 2 2 7 9 9 9 2 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 KEZ39439.1 - 0.0062 16.2 9.4 0.0062 16.2 6.5 7.4 2 2 5 7 7 6 3 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.1 KEZ39439.1 - 0.0091 16.0 10.3 0.0091 16.0 7.2 7.7 5 2 3 8 8 8 1 Leucine-zipper of ternary complex factor MIP1 NPV_P10 PF05531.7 KEZ39439.1 - 0.063 13.5 56.0 1.7 8.9 2.9 10.3 4 3 4 8 8 6 0 Nucleopolyhedrovirus P10 protein APG6 PF04111.7 KEZ39439.1 - 0.11 11.5 112.2 0.076 12.0 5.1 6.4 2 1 5 7 7 7 0 Autophagy protein Apg6 DUF2353 PF09789.4 KEZ39439.1 - 0.16 11.1 91.8 0.12 11.5 14.8 6.1 2 2 4 6 6 5 0 Uncharacterized coiled-coil protein (DUF2353) bZIP_1 PF00170.16 KEZ39439.1 - 0.23 11.4 0.0 0.23 11.4 0.0 14.8 6 4 9 17 17 16 0 bZIP transcription factor DUF4201 PF13870.1 KEZ39439.1 - 0.33 10.3 97.7 0.078 12.4 11.0 7.9 2 2 5 7 7 5 0 Domain of unknown function (DUF4201) CCDC155 PF14662.1 KEZ39439.1 - 1.3 8.5 123.3 0.037 13.6 25.3 7.0 2 2 4 6 6 6 0 Coiled-coil region of CCDC155 ERM PF00769.14 KEZ39439.1 - 1.6 8.2 125.0 0.066 12.7 13.2 6.7 1 1 5 6 6 5 0 Ezrin/radixin/moesin family HALZ PF02183.13 KEZ39439.1 - 3.1 7.5 0.0 2.3 8.0 0.2 14.7 10 3 6 16 16 15 0 Homeobox associated leucine zipper Atg14 PF10186.4 KEZ39439.1 - 3.6 6.4 95.8 0.02 13.8 2.9 6.3 2 1 3 5 5 5 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KEZ39439.1 - 7.2 5.9 107.0 3.1 7.1 2.3 5.9 2 2 2 4 4 4 0 Intermediate filament protein MFS_1 PF07690.11 KEZ39440.1 - 1.6e-33 115.8 13.8 5.1e-33 114.2 9.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39440.1 - 2.5e-08 32.9 6.1 1.7e-06 26.9 5.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KEZ39440.1 - 0.00022 19.7 14.9 0.00051 18.5 3.6 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 KEZ39440.1 - 0.0014 16.8 11.8 0.0019 16.4 3.4 2.6 3 0 0 3 3 3 2 Transmembrane secretion effector Folate_carrier PF01770.13 KEZ39440.1 - 0.021 13.3 1.1 0.051 12.0 0.1 1.8 1 1 0 2 2 2 0 Reduced folate carrier DUF1590 PF07629.6 KEZ39440.1 - 4.7 6.8 14.4 2.2 7.9 4.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) PTR2 PF00854.16 KEZ39441.1 - 4.4e-17 61.9 0.1 5.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 POT family Ank_2 PF12796.2 KEZ39442.1 - 5e-59 196.6 0.3 1.2e-18 67.2 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ39442.1 - 3.4e-56 184.3 2.1 3.9e-11 42.1 0.1 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 KEZ39442.1 - 2.1e-43 145.9 8.6 1.3e-12 47.8 0.1 5.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ39442.1 - 2.6e-43 145.0 5.4 7.9e-12 45.0 0.0 5.2 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ39442.1 - 2.8e-43 141.5 0.0 8e-07 28.7 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Nitro_FeMo-Co PF02579.12 KEZ39442.1 - 0.0021 18.0 0.3 2.2 8.4 0.0 3.2 1 1 2 3 3 3 2 Dinitrogenase iron-molybdenum cofactor DUF4350 PF14258.1 KEZ39442.1 - 0.026 14.7 1.7 4 7.7 0.0 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4350) NAD_binding_8 PF13450.1 KEZ39443.1 - 3.5e-13 49.3 0.9 8.6e-13 48.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Acetyltransf_1 PF00583.19 KEZ39443.1 - 9.3e-10 38.4 0.0 3e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ39443.1 - 3.6e-06 27.0 0.0 1e-05 25.5 0.0 1.8 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain DAO PF01266.19 KEZ39443.1 - 3.3e-05 22.9 0.9 6.3e-05 22.0 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ39443.1 - 4e-05 22.6 0.5 7e-05 21.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KEZ39443.1 - 0.00016 20.9 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KEZ39443.1 - 0.00016 20.8 0.2 0.00031 19.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Acetyltransf_CG PF14542.1 KEZ39443.1 - 0.00038 20.2 0.0 0.00091 19.0 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 KEZ39443.1 - 0.00046 20.2 0.0 0.0013 18.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAD_oxidored PF12831.2 KEZ39443.1 - 0.00065 18.8 0.4 0.0012 18.0 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ39443.1 - 0.0019 18.5 1.1 0.0092 16.3 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ39443.1 - 0.003 16.6 0.3 0.0053 15.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ39443.1 - 0.0031 16.0 1.0 0.0045 15.5 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KEZ39443.1 - 0.0036 17.3 0.2 0.009 16.0 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ39443.1 - 0.011 15.5 0.2 0.066 13.0 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FR47 PF08445.5 KEZ39443.1 - 0.018 14.7 0.0 0.065 13.0 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 KEZ39443.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Trp_halogenase PF04820.9 KEZ39443.1 - 0.1 11.2 0.4 0.16 10.5 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Methyltransf_23 PF13489.1 KEZ39444.1 - 7.9e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39444.1 - 4.3e-11 43.1 0.0 7.9e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39444.1 - 2.4e-09 37.5 0.0 1e-08 35.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39444.1 - 3.6e-09 37.1 0.0 4.2e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39444.1 - 1.4e-06 27.9 0.0 2e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ39444.1 - 7.9e-05 22.9 0.0 0.00019 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ39444.1 - 0.00014 21.0 0.0 0.0016 17.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEZ39444.1 - 0.00039 19.5 0.0 0.0027 16.8 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_PK PF05891.7 KEZ39444.1 - 0.004 16.4 0.0 0.008 15.4 0.0 1.5 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.4 KEZ39444.1 - 0.0081 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ39444.1 - 0.01 15.8 0.0 0.042 13.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KEZ39444.1 - 0.032 14.2 0.0 0.075 13.0 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 KEZ39444.1 - 0.043 13.2 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.7 KEZ39444.1 - 0.045 13.2 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.15 KEZ39444.1 - 0.093 11.7 0.0 0.6 9.1 0.0 2.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MFS_1 PF07690.11 KEZ39445.1 - 4.5e-20 71.6 29.9 4.5e-12 45.3 4.2 2.5 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1228 PF06779.9 KEZ39445.1 - 0.0015 18.5 4.7 0.019 15.0 0.2 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1228) Tox-GHH PF15636.1 KEZ39445.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin FAD_binding_3 PF01494.14 KEZ39446.1 - 2.5e-100 335.9 0.0 3.2e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ39446.1 - 4.4e-09 35.7 0.0 2.6e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ39446.1 - 5.6e-08 32.8 0.0 1.2e-07 31.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ39446.1 - 0.00047 20.2 0.2 0.0035 17.4 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ39446.1 - 0.0033 17.8 0.0 4.7 7.6 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ39446.1 - 0.0053 15.2 0.1 0.55 8.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 KEZ39446.1 - 0.027 13.5 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 KEZ39446.1 - 0.082 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 ThiF family FAA_hydrolase PF01557.13 KEZ39447.1 - 7.3e-59 198.8 0.0 1e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.20 KEZ39448.1 - 1.8e-06 27.9 1.3 0.00014 21.8 0.4 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Clavanin PF05452.6 KEZ39449.1 - 0.071 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Clavanin HET PF06985.6 KEZ39450.1 - 1.1e-27 96.8 0.0 2.2e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec3_C PF09763.4 KEZ39451.1 - 3.9e-189 630.1 0.0 5.7e-189 629.6 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KEZ39451.1 - 2.4e-30 104.2 0.1 5.8e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 KEZ39451.1 - 0.0039 15.7 1.4 0.055 11.9 0.0 2.8 3 0 0 3 3 3 1 Vps52 / Sac2 family Sec3_C_2 PF15278.1 KEZ39451.1 - 0.12 12.5 0.2 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Sec3 exocyst complex subunit COesterase PF00135.23 KEZ39453.1 - 0.072 11.7 0.2 0.63 8.6 0.0 1.7 1 1 1 2 2 2 0 Carboxylesterase family SIR2_2 PF13289.1 KEZ39453.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 SIR2-like domain RXT2_N PF08595.6 KEZ39455.1 - 4.7e-36 123.8 0.0 4.7e-36 123.8 0.0 3.1 5 0 0 5 5 5 1 RXT2-like, N-terminal Helicase_C_3 PF13625.1 KEZ39455.1 - 2.8e-25 88.5 0.0 7.5e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ39455.1 - 9.6e-10 38.5 0.0 1.4e-08 34.8 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEZ39455.1 - 9.8e-10 38.1 0.1 9.6e-09 34.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HNH_2 PF13391.1 KEZ39456.1 - 9.8e-05 22.0 0.3 0.00018 21.1 0.2 1.5 1 0 0 1 1 1 1 HNH endonuclease Herpes_BBRF1 PF04793.7 KEZ39456.1 - 0.06 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 BRRF1-like protein Gryzun PF07919.7 KEZ39458.1 - 1.1e-97 327.7 0.0 1.5e-97 327.1 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 KEZ39458.1 - 9e-73 244.7 0.3 4.9e-68 229.2 0.5 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 KEZ39458.1 - 0.022 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 KEZ39459.1 - 3.8e-31 108.7 0.3 6.1e-31 108.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ39459.1 - 5.9e-05 22.8 0.0 7.7e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ39459.1 - 0.00069 19.2 0.0 0.0039 16.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KEZ39459.1 - 0.044 13.3 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Pkinase PF00069.20 KEZ39460.1 - 2.3e-70 236.7 0.0 3.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39460.1 - 8.3e-31 106.9 0.0 1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39460.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ39460.1 - 0.0017 18.1 0.0 0.0088 15.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEZ39460.1 - 0.024 13.4 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KEZ39460.1 - 0.044 12.8 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2OG-FeII_Oxy_2 PF13532.1 KEZ39461.1 - 1.6e-29 103.1 0.0 6.4e-28 97.9 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KEZ39461.1 - 0.0039 17.6 0.0 0.0087 16.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_7 PF00840.15 KEZ39462.1 - 6.4e-206 683.8 17.4 7.4e-206 683.6 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fapy_DNA_glyco PF01149.19 KEZ39463.1 - 1.1e-26 93.5 1.4 2e-26 92.6 0.0 2.1 2 1 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KEZ39463.1 - 2.4e-20 72.0 0.0 4.9e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain MCPVI PF02993.9 KEZ39463.1 - 4.6 7.3 10.5 7.3 6.6 7.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Mating_N PF12731.2 KEZ39464.1 - 0.0094 15.7 0.3 1.3 8.9 0.1 2.6 2 0 0 2 2 2 2 Mating-type protein beta 1 zinc_ribbon_5 PF13719.1 KEZ39465.1 - 0.053 13.1 3.1 0.17 11.5 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KEZ39465.1 - 0.089 12.4 3.1 0.34 10.6 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 KEZ39465.1 - 0.97 9.2 4.4 0.33 10.7 0.9 1.7 2 0 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 KEZ39465.1 - 8.2 6.5 9.1 50 4.0 0.5 3.3 3 0 0 3 3 3 0 zinc-finger Clr5 PF14420.1 KEZ39466.1 - 1.9e-11 43.6 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Clr5 domain PH PF00169.24 KEZ39467.1 - 0.0043 17.2 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Arrestin_C PF02752.17 KEZ39468.1 - 2.4e-14 53.5 0.0 4.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KEZ39468.1 - 2.1e-13 50.3 0.0 3.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KEZ39468.1 - 0.0057 16.1 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like WD40 PF00400.27 KEZ39469.1 - 3.3e-23 80.6 6.3 3.4e-07 29.8 0.3 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 KEZ39469.1 - 9.1e-05 22.2 0.0 0.00043 20.0 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KEZ39469.1 - 0.00066 17.6 0.0 0.0009 17.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 KEZ39469.1 - 0.026 12.8 0.0 0.066 11.4 0.0 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.7 KEZ39469.1 - 0.089 12.4 0.0 20 4.9 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Lactamase_B_4 PF13691.1 KEZ39469.1 - 0.14 11.6 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 tRNase Z endonuclease EF_assoc_1 PF08355.7 KEZ39470.1 - 6.8e-34 114.9 0.3 1.4e-33 113.9 0.0 1.7 2 0 0 2 2 1 1 EF hand associated Miro PF08477.8 KEZ39470.1 - 2.9e-32 111.6 0.0 2e-16 60.5 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KEZ39470.1 - 5.4e-27 93.3 0.0 1.3e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KEZ39470.1 - 1.6e-19 69.8 0.0 1.6e-12 47.1 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_1 PF00036.27 KEZ39470.1 - 6.6e-10 37.5 2.3 0.00049 19.1 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KEZ39470.1 - 9.4e-10 38.4 0.4 0.0002 21.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEZ39470.1 - 1.8e-09 36.4 7.9 9.1e-05 21.6 1.7 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEZ39470.1 - 3e-09 35.9 5.3 0.00076 19.1 0.7 2.7 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.18 KEZ39470.1 - 3.8e-07 30.0 0.0 0.031 14.2 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEZ39470.1 - 2.3e-05 24.2 0.2 0.25 11.1 0.0 3.3 4 0 0 4 4 3 2 Dynamin family AAA_29 PF13555.1 KEZ39470.1 - 4.7e-05 22.8 0.0 0.0098 15.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ39470.1 - 5e-05 23.3 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 KEZ39470.1 - 0.0025 17.2 0.1 0.44 9.9 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain SPARC_Ca_bdg PF10591.4 KEZ39470.1 - 0.0037 17.2 0.0 5.2 7.1 0.0 3.2 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region ABC_tran PF00005.22 KEZ39470.1 - 0.0046 17.2 0.0 0.94 9.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 KEZ39470.1 - 0.011 15.7 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KEZ39470.1 - 0.011 15.8 0.0 0.59 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 KEZ39470.1 - 0.034 12.9 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.14 KEZ39470.1 - 0.035 13.5 0.1 3 7.2 0.1 3.2 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 KEZ39470.1 - 0.037 12.8 0.1 4 6.1 0.0 2.3 2 0 0 2 2 2 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 KEZ39470.1 - 0.042 13.3 0.1 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family EF-hand_10 PF14788.1 KEZ39470.1 - 0.058 13.0 0.5 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 KEZ39470.1 - 0.058 13.0 4.2 1.9 8.1 0.6 2.6 2 0 0 2 2 2 0 EF-hand domain pair MobB PF03205.9 KEZ39470.1 - 0.074 12.7 0.0 7.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KEZ39470.1 - 0.079 12.5 0.1 9.3 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KEZ39470.1 - 0.12 11.9 0.0 19 4.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UCR_Fe-S_N PF10399.4 KEZ39470.1 - 0.21 10.7 1.4 0.49 9.6 1.0 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal RPN7 PF10602.4 KEZ39471.1 - 4.3e-55 185.8 0.4 1.3e-54 184.2 0.0 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KEZ39471.1 - 8.2e-16 58.2 0.0 1.8e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 KEZ39471.1 - 0.13 12.1 0.6 0.61 10.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 KEZ39472.1 - 3.8e-40 137.9 0.0 5.5e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ39472.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Ribosomal_L33 PF00471.15 KEZ39473.1 - 4.8e-08 33.1 0.0 7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 CD99L2 PF12301.3 KEZ39475.1 - 0.025 14.2 0.2 0.038 13.6 0.1 1.4 1 1 0 1 1 1 0 CD99 antigen like protein 2 UNC-50 PF05216.8 KEZ39475.1 - 0.069 12.3 0.2 0.093 11.9 0.1 1.1 1 0 0 1 1 1 0 UNC-50 family NUC153 PF08159.7 KEZ39476.1 - 2.9e-11 42.7 0.2 5.3e-11 41.9 0.2 1.4 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KEZ39476.1 - 2.6e-08 33.4 0.1 8.7e-06 25.4 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat PNP_UDP_1 PF01048.15 KEZ39477.1 - 1.5e-38 132.0 0.2 2.8e-38 131.1 0.1 1.4 2 0 0 2 2 2 1 Phosphorylase superfamily PK_C PF02887.11 KEZ39477.1 - 0.15 11.6 0.1 1.9 8.0 0.1 2.4 1 1 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Med13_C PF06333.7 KEZ39478.1 - 7.3e-102 341.0 0.0 1e-101 340.5 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 KEZ39478.1 - 9.4e-08 31.1 0.0 5e-07 28.7 0.0 2.2 2 1 0 2 2 2 1 Mediator complex subunit 13 N-terminal K-cyclin_vir_C PF09080.5 KEZ39478.1 - 0.01 16.0 0.9 0.098 12.8 0.1 2.9 3 0 0 3 3 3 0 K cyclin, C terminal Atx10homo_assoc PF09759.4 KEZ39479.1 - 4.4e-08 32.7 0.0 1.4e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Zip PF02535.17 KEZ39479.1 - 9.6e-05 21.5 5.1 0.00015 20.8 3.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.11 KEZ39479.1 - 0.26 10.5 5.8 0.44 9.8 4.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF2796 PF10986.3 KEZ39479.1 - 0.88 9.5 24.4 1.7 8.5 16.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Zip PF02535.17 KEZ39480.1 - 2.8e-48 164.5 0.0 3.4e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF772 PF05598.6 KEZ39480.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Transposase domain (DUF772) Cation_efflux PF01545.16 KEZ39481.1 - 1.3e-36 126.1 6.5 1.7e-36 125.8 4.5 1.1 1 0 0 1 1 1 1 Cation efflux family MRP-L27 PF09809.4 KEZ39482.1 - 8.9e-16 57.5 0.3 1.2e-15 57.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Abhydrolase_3 PF07859.8 KEZ39483.1 - 7.3e-43 146.5 0.1 6.2e-33 114.1 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KEZ39483.1 - 4.7e-15 55.1 0.0 2.2e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KEZ39483.1 - 4.6e-05 23.2 0.0 9.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KEZ39483.1 - 4.9e-05 22.2 0.3 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.2 KEZ39483.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family WGG PF10273.4 KEZ39484.1 - 7.3e-26 90.0 0.1 1.1e-25 89.5 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 KEZ39484.1 - 0.095 12.7 0.4 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Nucleoplasmin PF03066.10 KEZ39484.1 - 0.29 10.6 5.4 0.38 10.2 3.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin SDA1 PF05285.7 KEZ39484.1 - 0.4 9.9 8.6 0.54 9.4 6.0 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 KEZ39484.1 - 0.5 10.1 2.9 0.82 9.4 2.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 KEZ39484.1 - 0.55 9.8 6.6 0.88 9.1 4.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KEZ39484.1 - 1.1 8.4 4.6 1.3 8.1 3.2 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KEZ39484.1 - 1.4 9.1 9.7 3.4 7.9 6.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Trypan_PARP PF05887.6 KEZ39484.1 - 2.7 7.7 6.0 3.9 7.2 4.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BSD PF03909.12 KEZ39485.1 - 9.3e-16 57.3 0.2 1.7e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 KEZ39485.1 - 0.0095 15.6 1.1 0.022 14.4 0.8 1.6 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAP1 PF08601.5 KEZ39486.1 - 9.4e-53 180.1 7.1 9.4e-53 180.1 4.9 2.4 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 KEZ39486.1 - 1.6e-07 31.1 13.9 6.3e-07 29.2 9.6 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ39486.1 - 0.00023 20.9 9.1 0.00053 19.7 6.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Adeno_PIX PF03955.9 KEZ39486.1 - 0.054 14.0 1.1 0.21 12.1 0.8 2.0 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 KEZ39486.1 - 0.093 12.3 1.7 0.18 11.4 1.2 1.4 1 0 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 KEZ39486.1 - 1.1 9.5 9.7 2.4 8.5 6.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor IFT57 PF10498.4 KEZ39486.1 - 1.9 7.1 7.1 1.8 7.2 2.1 2.4 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 SpoIIIAH PF12685.2 KEZ39486.1 - 4.4 6.7 8.4 10 5.5 5.8 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Fungal_trans PF04082.13 KEZ39487.1 - 4.7e-13 48.6 0.0 7.5e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ39487.1 - 2.9e-06 27.0 13.3 4.9e-06 26.3 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 KEZ39488.1 - 1.3e-09 37.2 0.0 7.3e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEZ39488.1 - 0.0067 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 KEZ39489.1 - 2.8e-139 464.2 0.0 3.5e-139 463.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Zn_clus PF00172.13 KEZ39490.1 - 2.8e-05 23.9 10.1 5.4e-05 23.0 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ39490.1 - 0.00021 20.2 0.0 0.00065 18.6 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KEZ39491.1 - 9.1e-18 64.4 0.3 6.8e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEZ39491.1 - 1.1e-08 35.0 0.5 2.4e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ39491.1 - 1.9e-07 30.3 4.9 2.7e-07 29.8 1.7 2.1 1 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ39491.1 - 1.2e-06 27.6 1.0 0.0016 17.3 0.4 2.1 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KEZ39491.1 - 4.9e-05 23.2 0.1 9.6e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ39491.1 - 5e-05 23.6 0.6 0.00012 22.4 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ39491.1 - 0.00021 20.5 0.1 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEZ39491.1 - 0.007 15.4 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KEZ39491.1 - 0.015 15.3 0.4 0.028 14.4 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 KEZ39491.1 - 0.019 14.6 0.2 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 KEZ39491.1 - 0.024 14.3 0.4 0.039 13.6 0.3 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KEZ39491.1 - 0.031 13.9 1.4 0.051 13.2 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KEZ39491.1 - 0.037 12.8 1.0 0.054 12.3 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 KEZ39491.1 - 0.039 12.4 0.8 0.06 11.8 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KEZ39491.1 - 0.052 12.4 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 KEZ39491.1 - 0.068 13.0 0.1 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KEZ39491.1 - 0.12 11.7 1.6 0.3 10.5 0.4 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Amidohydro_2 PF04909.9 KEZ39492.1 - 4.3e-40 137.9 0.1 5.5e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Pkinase PF00069.20 KEZ39493.1 - 1.1e-08 34.5 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39493.1 - 0.0014 17.7 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pyr_redox_3 PF13738.1 KEZ39494.1 - 4.6e-25 88.8 0.0 1.4e-21 77.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ39494.1 - 9e-16 57.1 0.0 1.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ39494.1 - 1.4e-14 53.8 0.0 6.8e-13 48.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEZ39494.1 - 4e-12 46.4 0.0 7.8e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ39494.1 - 2.3e-07 30.7 0.2 6.4e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ39494.1 - 6.5e-07 28.6 0.3 0.0076 15.3 0.0 2.5 3 0 0 3 3 3 2 Thi4 family Pyr_redox PF00070.22 KEZ39494.1 - 1.7e-05 25.1 0.7 0.046 14.1 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ39494.1 - 0.00015 21.5 0.7 0.14 11.9 0.1 3.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KEZ39494.1 - 0.00031 19.7 0.1 0.59 8.9 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 KEZ39494.1 - 0.0009 18.2 1.2 5.5 5.7 0.1 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEZ39494.1 - 0.0098 14.7 1.1 0.96 8.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KEZ39494.1 - 0.016 13.7 2.1 1.3 7.3 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.19 KEZ39494.1 - 0.019 13.8 9.0 0.17 10.7 0.1 4.2 3 2 0 4 4 4 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KEZ39494.1 - 0.07 13.2 0.0 2.4 8.2 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 KEZ39495.1 - 4.9e-32 111.6 0.1 5.9e-32 111.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ39495.1 - 1.7e-26 93.1 0.6 2.3e-26 92.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ39495.1 - 1.4e-13 50.9 0.1 2.4e-13 50.1 0.1 1.4 1 1 0 1 1 1 1 KR domain Glyco_transf_5 PF08323.6 KEZ39495.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF43 PF01861.11 KEZ39495.1 - 0.052 12.5 0.0 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF43 SnoaL PF07366.7 KEZ39496.1 - 0.0072 15.9 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 KEZ39497.1 - 5e-30 104.4 0.0 5.7e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ39497.1 - 6.4e-06 25.9 0.0 9.5e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ39497.1 - 0.014 15.2 0.0 0.82 9.4 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family Fe-ADH PF00465.14 KEZ39498.1 - 9.8e-104 346.8 0.0 1.2e-103 346.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KEZ39498.1 - 1.2e-14 54.2 0.0 9.9e-12 44.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 KEZ39498.1 - 0.0004 19.8 0.1 0.00075 18.9 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Pkinase PF00069.20 KEZ39499.1 - 2.3e-58 197.3 0.0 3.1e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39499.1 - 1.5e-30 106.1 0.0 2.1e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39499.1 - 1.5e-05 24.1 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ39499.1 - 0.0061 16.3 0.2 0.0061 16.3 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KEZ39499.1 - 0.033 13.2 0.0 0.07 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HECT PF00632.20 KEZ39500.1 - 3e-69 233.6 0.0 4.3e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fe_dep_repress PF01325.14 KEZ39500.1 - 0.21 11.5 0.1 0.57 10.1 0.1 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain zf-C2H2_2 PF12756.2 KEZ39501.1 - 2.4e-35 120.6 7.2 3.2e-28 97.7 0.8 3.7 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KEZ39501.1 - 1.4e-08 34.5 21.4 7.7e-06 25.8 2.8 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ39501.1 - 1.5e-06 28.2 4.3 1.5e-06 28.2 3.0 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type SnoaL_2 PF12680.2 KEZ39501.1 - 0.012 16.0 0.1 0.077 13.4 0.1 2.1 2 0 0 2 2 2 0 SnoaL-like domain zf-DBF PF07535.7 KEZ39501.1 - 0.69 9.6 8.8 0.66 9.7 1.1 3.2 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.21 KEZ39501.1 - 1.4 9.3 21.2 2.1 8.8 1.0 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KEZ39501.1 - 9.1 6.3 10.6 17 5.4 1.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DHBP_synthase PF00926.14 KEZ39502.1 - 1.7e-69 232.9 0.0 6.1e-69 231.1 0.0 1.7 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase EII-Sor PF03609.9 KEZ39503.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 PTS system sorbose-specific iic component NYN PF01936.13 KEZ39504.1 - 0.002 18.4 0.0 0.0039 17.4 0.0 1.4 1 0 0 1 1 1 1 NYN domain zf-Nse PF11789.3 KEZ39505.1 - 1e-22 79.3 0.4 1.9e-22 78.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KEZ39505.1 - 5.3e-05 22.8 0.1 0.00011 21.8 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KEZ39505.1 - 0.009 15.5 0.2 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.1 KEZ39505.1 - 0.032 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 KEZ39505.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger FUSC PF04632.7 KEZ39505.1 - 1.2 7.4 3.3 1.8 6.8 2.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 KEZ39505.1 - 1.8 7.5 7.1 3 6.7 4.9 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3433 PF11915.3 KEZ39506.1 - 9.9e-28 96.1 6.4 4.4e-17 62.0 0.1 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF1146 PF06612.6 KEZ39506.1 - 0.00092 19.0 0.4 0.00092 19.0 0.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1146) DUF4381 PF14316.1 KEZ39506.1 - 2.3 8.3 5.7 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Complex1_LYR PF05347.10 KEZ39507.1 - 9.9e-13 47.6 0.2 2.5e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEZ39507.1 - 1.7e-10 40.9 0.1 4.9e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Complex1_LYR-like bZIP_1 PF00170.16 KEZ39508.1 - 1.2e-06 28.3 2.2 2.3e-06 27.4 1.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF4175 PF13779.1 KEZ39508.1 - 4.1 4.9 16.7 6.6 4.3 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 KEZ39508.1 - 6.9 5.4 10.7 10 4.8 7.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_7 PF00840.15 KEZ39509.1 - 3.8e-153 509.9 7.1 4.6e-153 509.6 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Asp PF00026.18 KEZ39510.1 - 0.0045 16.2 0.0 0.052 12.7 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Herpes_gE PF02480.11 KEZ39510.1 - 0.019 13.2 0.0 0.03 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E adh_short PF00106.20 KEZ39511.1 - 1.5e-25 90.0 0.2 2e-25 89.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ39511.1 - 2e-18 67.0 0.1 2.5e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ39511.1 - 3.2e-05 24.0 0.3 0.0001 22.3 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 KEZ39511.1 - 0.00064 19.7 0.1 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain DUF1776 PF08643.5 KEZ39511.1 - 0.0013 17.9 0.0 0.0026 16.9 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 KEZ39511.1 - 0.03 14.7 0.1 0.054 13.9 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KEZ39511.1 - 0.077 12.4 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ApbA PF02558.11 KEZ39511.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.21 KEZ39511.1 - 0.13 11.8 0.5 0.25 10.8 0.4 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Tim17 PF02466.14 KEZ39513.1 - 5e-34 117.1 6.1 6.3e-34 116.7 4.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family APH PF01636.18 KEZ39514.1 - 1.1e-09 38.3 0.0 3.1e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KEZ39514.1 - 0.076 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Peptidase_M20 PF01546.23 KEZ39515.1 - 3.8e-21 75.4 0.0 7.6e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KEZ39515.1 - 2.6e-17 61.9 2.0 0.00053 19.7 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 KEZ39515.1 - 0.00017 21.2 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Methyltransf_23 PF13489.1 KEZ39516.1 - 2.8e-13 49.8 0.0 3.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39516.1 - 0.0029 18.0 0.0 0.0065 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39516.1 - 0.01 15.4 0.0 0.025 14.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain RuvA_C PF07499.8 KEZ39516.1 - 0.034 14.3 0.1 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain Methyltransf_12 PF08242.7 KEZ39516.1 - 0.13 12.7 0.0 0.55 10.7 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KEZ39517.1 - 4.5e-60 202.7 0.0 6e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.21 KEZ39518.1 - 4.5e-17 61.7 0.0 5.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEZ39518.1 - 0.026 14.4 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 RWD domain Band_7 PF01145.20 KEZ39519.1 - 8.6e-32 110.4 0.4 1.7e-31 109.5 0.3 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KEZ39519.1 - 0.033 13.7 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Sec7_N PF12783.2 KEZ39520.1 - 1.4e-35 122.2 1.0 1.6e-34 118.7 0.1 3.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KEZ39520.1 - 1.7e-05 24.2 0.1 0.0016 17.9 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Velvet PF11754.3 KEZ39521.1 - 2.5e-49 167.6 3.4 1.3e-48 165.3 2.4 1.9 1 1 0 1 1 1 1 Velvet factor Peptidase_M4 PF01447.13 KEZ39522.1 - 7.9e-29 100.7 2.5 1.2e-28 100.1 1.7 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M4_C PF02868.10 KEZ39522.1 - 2.5e-23 82.5 1.3 2.4e-18 66.4 0.0 2.9 2 1 1 3 3 3 2 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M13 PF01431.16 KEZ39522.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M13 DUF4649 PF15507.1 KEZ39522.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Mem_trans PF03547.13 KEZ39523.1 - 0.79 7.9 2.8 0.83 7.8 2.0 1.0 1 0 0 1 1 1 0 Membrane transport protein Mucin PF01456.12 KEZ39523.1 - 0.9 9.3 17.6 1.1 9.0 12.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3437 PF11919.3 KEZ39524.1 - 3.7e-32 109.8 0.0 1.1e-31 108.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Cutinase PF01083.17 KEZ39525.1 - 7.5e-52 175.6 7.7 8.6e-52 175.4 5.4 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KEZ39525.1 - 4.1e-06 26.3 0.0 6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 KEZ39525.1 - 0.0043 16.9 0.1 0.0077 16.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ39525.1 - 0.0059 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.6 KEZ39525.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 KEZ39525.1 - 0.15 11.8 0.5 0.62 9.8 0.1 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Complex1_51K PF01512.12 KEZ39526.1 - 2.7e-46 157.0 0.0 4.1e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KEZ39526.1 - 2.8e-18 64.7 1.1 2.8e-18 64.7 0.8 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KEZ39526.1 - 4.2e-10 39.3 0.0 2e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 SLBB domain PEX11 PF05648.9 KEZ39527.1 - 6.7e-27 94.1 0.0 6.5e-26 90.9 0.0 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3186 PF11382.3 KEZ39527.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) ATP-synt_E PF05680.7 KEZ39527.1 - 1.5 8.7 10.3 26 4.8 7.1 2.3 1 1 0 1 1 1 0 ATP synthase E chain Smr PF01713.16 KEZ39528.1 - 3.3e-10 40.0 0.1 8.7e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 KEZ39528.1 - 0.024 14.1 0.0 0.07 12.6 0.0 1.8 2 0 0 2 2 2 0 CUE domain GMC_oxred_N PF00732.14 KEZ39529.1 - 1.2e-56 192.0 0.0 1.5e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39529.1 - 2e-29 102.7 0.2 3.3e-29 102.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ39529.1 - 5.9e-05 22.0 0.0 0.081 11.7 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 KEZ39529.1 - 0.00011 21.2 0.1 0.048 12.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ39529.1 - 0.0008 19.5 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ39529.1 - 0.0083 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ39529.1 - 0.014 15.4 0.1 0.043 13.8 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ39529.1 - 0.019 14.0 0.3 0.22 10.6 0.0 2.6 3 0 0 3 3 3 0 Thi4 family Pyr_redox_2 PF07992.9 KEZ39529.1 - 0.026 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ39529.1 - 0.1 12.3 0.0 0.67 9.7 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding NT5C PF06941.7 KEZ39529.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) APH PF01636.18 KEZ39530.1 - 1.2e-11 44.8 0.1 3.4e-11 43.3 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ39530.1 - 6.7e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KEZ39530.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PRKCSH-like PF12999.2 KEZ39532.1 - 5.9e-41 139.9 7.9 2e-23 82.8 0.5 3.0 2 1 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KEZ39532.1 - 5.4e-32 110.4 0.1 1.4e-31 109.0 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KEZ39532.1 - 5.8e-10 39.8 0.8 2e-09 38.1 0.6 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DFF-C PF09033.5 KEZ39532.1 - 0.0033 17.2 0.3 0.0086 15.9 0.2 1.7 1 0 0 1 1 1 1 DNA Fragmentation factor 45kDa, C terminal domain zf-ZPR1 PF03367.8 KEZ39532.1 - 0.07 12.2 0.3 0.16 11.0 0.2 1.6 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Mnd1 PF03962.10 KEZ39532.1 - 0.61 9.7 8.1 0.071 12.7 1.7 2.3 2 1 1 3 3 3 0 Mnd1 family Fzo_mitofusin PF04799.8 KEZ39532.1 - 2.4 7.5 5.6 5.8 6.2 0.3 2.3 2 0 0 2 2 2 0 fzo-like conserved region ADIP PF11559.3 KEZ39532.1 - 4.9 7.0 12.7 0.69 9.8 0.2 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding FAT PF02259.18 KEZ39533.1 - 1.6e-123 412.1 3.2 1.6e-123 412.1 2.2 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KEZ39533.1 - 1.1e-62 211.6 0.3 1.8e-62 210.8 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KEZ39533.1 - 3.2e-61 205.9 2.2 5.4e-59 198.7 0.8 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KEZ39533.1 - 9.3e-44 147.6 0.6 5.1e-43 145.2 0.0 2.7 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 KEZ39533.1 - 2.1e-15 56.7 19.3 0.0044 17.2 0.2 9.3 4 2 6 10 10 10 7 HEAT repeats FATC PF02260.15 KEZ39533.1 - 2.7e-14 52.2 0.1 7.2e-14 50.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KEZ39533.1 - 1.9e-11 43.0 24.7 0.0051 16.7 0.0 11.5 13 0 0 13 13 13 3 HEAT repeat HEAT_EZ PF13513.1 KEZ39533.1 - 3.9e-08 33.5 27.1 3.6e-06 27.3 0.1 11.8 10 3 3 13 13 12 2 HEAT-like repeat Cnd1 PF12717.2 KEZ39533.1 - 5.8e-05 23.0 1.0 0.063 13.1 0.1 4.6 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Apc3 PF12895.2 KEZ39533.1 - 0.0045 17.1 0.8 1.6 8.9 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KEZ39533.1 - 0.06 13.1 1.8 4.4 7.3 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex24p PF06398.6 KEZ39535.1 - 2.2e-97 326.0 0.0 2.8e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin COesterase PF00135.23 KEZ39536.1 - 4.1e-96 322.8 0.0 5.3e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ39536.1 - 5.3e-07 29.4 0.1 2.4e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ39536.1 - 1.7e-05 24.1 0.1 3.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.5 KEZ39536.1 - 0.038 12.8 0.0 0.51 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) AcetylCoA_hyd_C PF13336.1 KEZ39536.1 - 0.043 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain SNF2_N PF00176.18 KEZ39538.1 - 2.1e-21 76.0 0.0 1.5e-19 69.8 0.0 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ39538.1 - 3.2e-07 30.0 0.0 6.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ39538.1 - 0.0018 17.7 0.2 0.026 13.9 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase zf-ribbon_3 PF13248.1 KEZ39538.1 - 0.025 13.7 1.2 0.048 12.8 0.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain COesterase PF00135.23 KEZ39539.1 - 4.2e-67 227.0 0.0 5e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ39539.1 - 3.5e-09 36.5 0.0 5.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KEZ39539.1 - 0.0027 16.4 0.0 0.0043 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KEZ39539.1 - 0.0085 15.8 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox_2 PF07992.9 KEZ39540.1 - 5.8e-09 36.1 0.2 6.2e-08 32.7 0.1 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ39540.1 - 1.7e-05 24.6 0.0 0.00037 20.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KEZ39540.1 - 4.7e-05 22.4 0.5 0.0018 17.2 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ39540.1 - 0.00039 20.5 0.3 0.013 15.5 0.1 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEZ39540.1 - 0.0014 17.2 0.3 0.0028 16.3 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KEZ39540.1 - 0.0054 16.7 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ39540.1 - 0.0075 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEZ39540.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Malic_M PF03949.10 KEZ39540.1 - 0.054 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DUF4147 PF13660.1 KEZ39540.1 - 0.093 11.8 0.0 0.26 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) ThiF PF00899.16 KEZ39540.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 KEZ39540.1 - 0.15 10.9 1.7 0.44 9.3 0.9 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KEZ39540.1 - 0.16 12.4 0.2 0.83 10.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1996 PF09362.5 KEZ39541.1 - 9.5e-87 290.5 2.5 1.2e-86 290.2 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 KEZ39542.1 - 1e-80 270.8 2.5 1.2e-80 270.5 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ferric_reduct PF01794.14 KEZ39544.1 - 7.8e-17 61.5 14.3 2e-16 60.1 9.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEZ39544.1 - 7.6e-10 38.9 0.0 7.9e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEZ39544.1 - 1.8e-08 34.2 0.0 0.00028 20.6 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain AftA_C PF12249.3 KEZ39546.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Ead_Ea22 PF13935.1 KEZ39546.1 - 0.085 13.1 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Ead/Ea22-like protein Fungal_trans PF04082.13 KEZ39547.1 - 3.1e-05 23.0 0.0 6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p31comet PF06581.7 KEZ39547.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding SnoaL PF07366.7 KEZ39548.1 - 0.002 17.6 0.1 0.99 8.9 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KEZ39548.1 - 0.071 13.5 0.1 0.17 12.3 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like domain Methyltransf_23 PF13489.1 KEZ39549.1 - 1.6e-21 76.7 0.0 2.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39549.1 - 9.2e-14 51.2 0.1 1e-12 47.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39549.1 - 1.3e-12 48.2 0.1 1.4e-11 44.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39549.1 - 9.3e-11 42.0 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39549.1 - 9e-10 38.9 0.0 4.8e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ39549.1 - 1.1e-06 28.8 0.0 3.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ39549.1 - 1.2e-05 25.3 0.0 2.9e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ39549.1 - 2.1e-05 23.6 0.0 9.8e-05 21.4 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ39549.1 - 8.3e-05 22.0 0.0 0.00035 19.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KEZ39549.1 - 0.00078 19.4 0.0 0.0021 18.1 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.15 KEZ39549.1 - 0.00099 18.2 0.0 0.0026 16.8 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KEZ39549.1 - 0.0071 15.5 0.0 0.014 14.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KEZ39549.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_16 PF10294.4 KEZ39549.1 - 0.024 14.0 0.0 0.054 12.9 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KEZ39549.1 - 0.047 12.8 0.0 0.53 9.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4246 PF14033.1 KEZ39550.1 - 1.2e-172 575.0 0.0 1.7e-172 574.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.1 KEZ39550.1 - 0.027 14.9 0.1 0.082 13.4 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KEZ39550.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 KEZ39551.1 - 9.2e-28 96.9 34.9 9.2e-28 96.9 24.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Tannase PF07519.6 KEZ39552.1 - 1.2e-89 301.1 0.6 1.9e-89 300.6 0.4 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 KEZ39552.1 - 0.0011 18.2 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ39552.1 - 0.022 14.5 0.0 0.29 10.8 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Polysacc_deac_1 PF01522.16 KEZ39553.1 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase ComA PF02679.10 KEZ39554.1 - 2.2e-81 272.5 0.0 2.5e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) HMGL-like PF00682.14 KEZ39554.1 - 0.038 13.6 0.0 6.7 6.2 0.0 2.7 2 1 0 3 3 3 0 HMGL-like Sugar_tr PF00083.19 KEZ39555.1 - 2.4e-97 326.3 14.0 2.8e-97 326.1 9.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39555.1 - 2.4e-24 85.7 26.0 1.1e-18 67.0 1.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KEZ39555.1 - 0.00059 18.0 2.3 0.00061 17.9 0.4 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 KEZ39555.1 - 0.0022 17.9 1.1 1.2 9.1 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) Fungal_trans_2 PF11951.3 KEZ39556.1 - 2.2e-08 33.1 0.1 1.1e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.17 KEZ39557.1 - 2e-63 214.5 0.0 2.7e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 KEZ39558.1 - 1.8e-30 105.7 0.4 1.2e-26 93.2 0.3 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Cyclase PF04199.8 KEZ39559.1 - 3e-19 69.3 0.0 4.2e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase DIOX_N PF14226.1 KEZ39561.1 - 1.8e-31 109.0 0.0 2.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEZ39561.1 - 2.2e-24 85.5 0.0 4.1e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_23 PF13489.1 KEZ39562.1 - 1.9e-13 50.4 0.0 2.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39562.1 - 1.9e-08 34.6 0.0 2.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39562.1 - 3.9e-07 30.4 0.0 5.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39562.1 - 8.6e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39562.1 - 2.9e-06 27.8 0.0 4.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ39562.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KEZ39562.1 - 0.0018 18.2 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_25 PF13649.1 KEZ39562.1 - 0.0021 18.4 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 KEZ39562.1 - 0.0047 16.4 0.0 0.0063 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 KEZ39562.1 - 0.012 14.7 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KEZ39562.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KEZ39562.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KEZ39563.1 - 1.9e-18 66.7 0.0 2.9e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39563.1 - 1.6e-13 50.9 0.0 3.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39563.1 - 1.8e-10 41.1 0.0 7.1e-10 39.2 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39563.1 - 1.4e-09 38.5 0.0 2e-08 34.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39563.1 - 2.3e-09 36.9 0.0 1.9e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ39563.1 - 1.9e-07 31.3 0.0 6.7e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ39563.1 - 1.9e-05 23.9 0.0 0.00014 21.0 0.0 2.2 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEZ39563.1 - 5.7e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KEZ39563.1 - 7.3e-05 22.8 0.1 0.0002 21.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ39563.1 - 0.00011 22.1 0.0 0.0016 18.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ39563.1 - 0.00081 18.8 0.0 0.0033 16.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KEZ39563.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 KEZ39563.1 - 0.027 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KEZ39563.1 - 0.042 12.9 0.0 0.069 12.2 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 KEZ39563.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_15 PF09445.5 KEZ39563.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pkinase PF00069.20 KEZ39564.1 - 1.2e-17 63.9 0.0 5.3e-17 61.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39564.1 - 2.3e-08 33.4 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Methyltransf_23 PF13489.1 KEZ39564.1 - 1.2e-06 28.3 0.0 2.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CFEM PF05730.6 KEZ39566.1 - 1.2e-07 31.4 6.3 2.4e-07 30.4 4.4 1.5 1 0 0 1 1 1 1 CFEM domain Herpes_gE PF02480.11 KEZ39566.1 - 0.015 13.6 1.6 0.017 13.4 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Phage_GP20 PF06810.6 KEZ39566.1 - 0.052 12.9 2.1 0.074 12.4 1.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 KEZ39566.1 - 0.19 11.2 8.9 3.5 7.1 0.1 2.2 2 0 0 2 2 2 0 IncA protein MtrF PF09472.5 KEZ39566.1 - 0.24 10.6 3.4 0.42 9.8 2.4 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Fungal_trans PF04082.13 KEZ39567.1 - 1.6e-24 86.2 0.0 2.6e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.17 KEZ39568.1 - 1.1e-143 478.9 0.6 4.3e-73 246.2 0.0 3.1 1 1 2 3 3 3 3 Aldehyde dehydrogenase family Aa_trans PF01490.13 KEZ39569.1 - 3.1e-26 91.8 37.3 4.8e-25 87.9 25.8 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein ADH_N PF08240.7 KEZ39570.1 - 9.7e-32 108.9 2.6 2e-31 107.9 1.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ39570.1 - 3.7e-14 52.3 0.0 5.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KEZ39570.1 - 0.008 16.2 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 KEZ39570.1 - 0.072 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 KEZ39570.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Transketolase_N PF00456.16 KEZ39571.1 - 2.7e-117 391.3 0.0 3.6e-117 390.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KEZ39571.1 - 8e-42 142.7 0.0 1.3e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 KEZ39571.1 - 1.7e-07 30.4 0.0 2.7e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 KEZ39571.1 - 3e-05 23.9 0.0 7.6e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 KEZ39571.1 - 0.0092 14.7 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Fungal_trans_2 PF11951.3 KEZ39572.1 - 6.7e-16 57.8 2.1 4.4e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 KEZ39573.1 - 7.4e-51 172.6 0.0 8.8e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.23 KEZ39574.1 - 5.1e-107 358.8 0.0 6.4e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ39574.1 - 1.8e-07 30.9 0.0 4.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 KEZ39575.1 - 7.7e-80 268.6 20.5 8.8e-80 268.4 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39575.1 - 4.9e-16 58.3 20.7 4.9e-16 58.3 14.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ39575.1 - 4.6e-10 38.4 18.3 6.2e-06 24.8 2.6 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein EF-hand_4 PF12763.2 KEZ39576.1 - 1.2e-14 53.9 0.0 1.8e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KEZ39576.1 - 0.00067 18.7 0.1 0.038 13.2 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KEZ39576.1 - 0.0062 16.3 3.9 0.14 12.1 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 KEZ39576.1 - 0.013 15.6 0.0 0.11 12.6 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain pair Polysacc_deac_1 PF01522.16 KEZ39577.1 - 2.6e-31 107.8 0.0 3.6e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KEZ39577.1 - 1.2e-05 25.1 22.0 2.2e-05 24.3 15.2 1.4 1 0 0 1 1 1 1 Chitin recognition protein Hemocyanin_N PF03722.9 KEZ39577.1 - 0.037 14.1 0.0 12 6.0 0.0 2.1 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain Glyco_hydro_57 PF03065.10 KEZ39577.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NAD_binding_8 PF13450.1 KEZ39580.1 - 2.6e-11 43.3 0.0 5.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ39580.1 - 1.4e-07 30.7 1.0 2.9e-07 29.6 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ39580.1 - 4.4e-06 25.8 0.8 8e-06 24.9 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEZ39580.1 - 5.5e-06 25.7 0.4 8.2e-06 25.1 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ39580.1 - 2.1e-05 23.2 0.2 3.1e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KEZ39580.1 - 2.6e-05 24.5 0.1 5.4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ39580.1 - 0.00029 20.0 0.0 0.00065 18.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KEZ39580.1 - 0.00037 20.6 0.0 0.0023 18.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ39580.1 - 0.00097 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ39580.1 - 0.0011 18.9 0.1 0.0029 17.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ39580.1 - 0.011 14.7 0.2 0.017 14.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KEZ39580.1 - 0.077 11.8 0.3 0.12 11.1 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 KEZ39582.1 - 2.8e-14 53.3 0.0 4.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Peptidase_S8 PF00082.17 KEZ39583.1 - 3.5e-48 164.1 13.1 5.4e-48 163.5 9.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEZ39583.1 - 3.9e-09 36.9 0.0 1.7e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_23 PF13489.1 KEZ39585.1 - 5.7e-23 81.4 0.0 8.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39585.1 - 7.6e-11 42.3 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39585.1 - 3.9e-10 40.2 0.0 6.9e-09 36.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39585.1 - 8.6e-10 38.3 0.0 6.4e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ39585.1 - 3.9e-08 33.5 0.0 1.7e-07 31.5 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39585.1 - 2.6e-06 27.8 0.0 2.3e-05 24.7 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ39585.1 - 1.5e-05 24.2 0.0 0.00016 20.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEZ39585.1 - 8.3e-05 22.6 0.0 0.00024 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ39585.1 - 0.00033 19.7 0.0 0.001 18.1 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ39585.1 - 0.004 16.5 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KEZ39585.1 - 0.0042 17.1 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KEZ39585.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 KEZ39585.1 - 0.08 12.1 0.0 0.35 10.0 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase FmrO PF07091.6 KEZ39585.1 - 0.08 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.6 KEZ39585.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.14 KEZ39585.1 - 0.14 11.7 0.0 0.8 9.1 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fe-ADH PF00465.14 KEZ39586.1 - 1.3e-75 254.3 0.6 1.5e-75 254.1 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KEZ39586.1 - 9.9e-15 54.5 0.1 1.4e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1967 PF09269.6 KEZ39586.1 - 0.17 11.5 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Dioxygenase_C PF00775.16 KEZ39587.1 - 3.9e-52 176.1 0.0 6.6e-52 175.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEZ39587.1 - 4.2e-19 68.3 0.2 8.4e-19 67.3 0.0 1.6 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEZ39587.1 - 0.00073 19.5 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CoA_transf_3 PF02515.12 KEZ39588.1 - 1.4e-20 73.3 0.1 6.7e-08 31.9 0.0 3.2 3 0 0 3 3 3 3 CoA-transferase family III p450 PF00067.17 KEZ39589.1 - 2.4e-58 197.7 0.0 1.5e-56 191.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.14 KEZ39590.1 - 1.3e-47 162.6 0.0 1.7e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Carboxyl_trans PF01039.17 KEZ39591.1 - 1e-101 340.7 0.0 1.4e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KEZ39591.1 - 3.7e-65 219.1 0.0 6.6e-65 218.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KEZ39591.1 - 4.2e-29 100.6 0.0 8.2e-29 99.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KEZ39591.1 - 5.3e-24 84.4 0.0 1.8e-23 82.7 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KEZ39591.1 - 2.7e-13 50.0 0.0 6.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KEZ39591.1 - 1.1e-11 44.1 4.3 5.7e-11 41.9 2.7 2.2 1 1 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KEZ39591.1 - 9.4e-10 38.2 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KEZ39591.1 - 1.3e-09 37.2 0.0 1.2e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEZ39591.1 - 1.4e-09 37.5 0.1 2.7e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KEZ39591.1 - 1.5e-06 28.1 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KEZ39591.1 - 5.6e-06 25.9 0.1 0.0024 17.4 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.6 KEZ39591.1 - 0.015 14.8 0.1 0.032 13.7 0.0 1.5 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_2 PF12700.2 KEZ39591.1 - 0.29 10.2 0.0 9 5.3 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein AMP-binding PF00501.23 KEZ39592.1 - 2.3e-72 243.6 0.2 1.8e-38 132.0 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ39592.1 - 2.2e-11 44.5 0.0 9e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH PF00378.15 KEZ39593.1 - 4.8e-41 140.4 0.0 8.1e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 KEZ39593.1 - 9.3e-21 74.5 0.3 2.6e-17 63.2 0.0 2.4 1 1 1 2 2 2 2 HMGL-like Fungal_trans_2 PF11951.3 KEZ39594.1 - 0.00098 17.8 0.4 0.0057 15.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox PF00070.22 KEZ39597.1 - 4.9e-13 49.2 0.1 8.4e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ39597.1 - 1.1e-07 31.9 0.0 0.00043 20.2 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ39597.1 - 3.5e-06 26.1 0.0 0.0031 16.4 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ39597.1 - 1.5e-05 25.1 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEZ39597.1 - 0.0043 15.7 0.0 0.13 10.8 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase K_oxygenase PF13434.1 KEZ39597.1 - 0.0069 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 KEZ39597.1 - 0.011 14.6 0.0 0.098 11.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KEZ39597.1 - 0.033 14.4 0.0 0.17 12.1 0.0 2.1 3 0 0 3 3 3 0 Putative NAD(P)-binding TrkA_N PF02254.13 KEZ39597.1 - 0.037 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KEZ39597.1 - 0.04 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNase_NucA_NucB PF14040.1 KEZ39600.1 - 1.8e-06 28.0 1.9 5.5e-06 26.5 0.0 2.5 3 0 0 3 3 3 1 Deoxyribonuclease NucA/NucB CPG4 PF15481.1 KEZ39600.1 - 0.18 12.1 6.3 2.8 8.3 0.8 2.3 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 tRNA-synt_1g PF09334.6 KEZ39601.1 - 8.9e-116 386.7 0.0 1.4e-115 386.0 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEZ39601.1 - 6.9e-23 80.4 2.1 2.4e-09 35.7 0.1 3.5 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.1 KEZ39601.1 - 5e-16 59.1 0.0 1.5e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 KEZ39601.1 - 9.4e-10 38.0 0.0 8.8e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Acetyltransf_8 PF13523.1 KEZ39601.1 - 6.6e-06 26.0 0.0 0.0033 17.3 0.0 2.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Anticodon_1 PF08264.8 KEZ39601.1 - 0.006 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Acetyltransf_1 PF00583.19 KEZ39601.1 - 0.02 14.9 0.1 0.071 13.1 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KEZ39601.1 - 0.036 13.9 0.0 0.46 10.4 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1754 PF08555.5 KEZ39602.1 - 9.8e-11 42.1 15.3 1.5e-10 41.4 10.6 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Adaptin_binding PF10199.4 KEZ39602.1 - 0.46 10.7 11.0 0.73 10.1 7.6 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TPK_catalytic PF04263.11 KEZ39602.1 - 1.6 8.3 3.8 2.5 7.7 0.1 2.1 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain CDC27 PF09507.5 KEZ39602.1 - 2.5 7.2 18.3 3.1 6.9 12.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sigma70_ner PF04546.8 KEZ39602.1 - 2.7 7.5 13.0 4 6.9 9.0 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region CTP_transf_1 PF01148.15 KEZ39604.1 - 7.9e-07 28.9 9.5 7.9e-07 28.9 6.6 3.0 3 1 0 3 3 3 1 Cytidylyltransferase family DUF3619 PF12279.3 KEZ39604.1 - 0.091 12.8 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) ORC2 PF04084.9 KEZ39605.1 - 3.3e-96 321.9 0.0 4e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 SEEEED PF14797.1 KEZ39605.1 - 3.8 7.6 15.6 2.3 8.3 1.2 2.4 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex PGP_phosphatase PF09419.5 KEZ39606.1 - 9.3e-62 207.3 0.0 1.3e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KEZ39606.1 - 5.8e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEZ39606.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CutC PF03932.9 KEZ39607.1 - 9.3e-34 116.4 0.0 1.7e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 CutC family TGT PF01702.13 KEZ39608.1 - 3e-33 115.0 0.0 4e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase CENP-I PF07778.6 KEZ39609.1 - 2.4e-81 273.4 0.0 4.7e-57 193.3 0.0 2.8 2 1 1 3 3 3 2 Mis6 ADH_zinc_N_2 PF13602.1 KEZ39610.1 - 4.6e-18 66.3 0.0 1.1e-17 65.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEZ39610.1 - 9.5e-08 31.6 0.7 1.7e-07 30.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ39610.1 - 1.8e-05 24.4 0.1 0.0061 16.3 0.0 3.3 2 2 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KEZ39610.1 - 0.0007 19.2 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.15 KEZ39610.1 - 0.0019 18.1 0.1 0.0041 17.0 0.0 1.5 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus AMP-binding PF00501.23 KEZ39610.1 - 0.01 14.2 0.0 0.18 10.1 0.0 2.2 2 1 0 2 2 2 0 AMP-binding enzyme CAS_CSE1 PF03378.10 KEZ39611.1 - 1.4e-151 504.7 0.5 4.7e-151 502.9 0.0 2.1 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KEZ39611.1 - 2.2e-150 500.3 1.5 3.6e-150 499.6 1.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KEZ39611.1 - 1.5e-12 47.2 0.8 1.2e-11 44.3 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KEZ39611.1 - 0.027 14.4 0.4 1.4 8.8 0.0 3.8 3 1 0 3 3 3 0 Exportin 1-like protein adh_short PF00106.20 KEZ39612.1 - 7.6e-16 58.4 3.6 1.2e-15 57.8 2.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ39612.1 - 3.4e-06 26.8 1.0 7.1e-06 25.8 0.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ39612.1 - 0.00016 21.2 0.0 0.00019 20.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEZ39612.1 - 0.00099 18.9 0.0 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ39612.1 - 0.038 13.9 2.2 0.34 10.8 1.5 2.2 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KEZ39612.1 - 0.082 12.0 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cas6 PF09559.5 KEZ39612.1 - 0.12 12.1 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Cas6 Crispr CoA_transf_3 PF02515.12 KEZ39613.1 - 3.6e-49 166.6 0.0 4.9e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.15 KEZ39614.1 - 3.9e-106 354.1 0.0 1e-105 352.7 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KEZ39614.1 - 5.3e-56 189.0 0.0 9.3e-56 188.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KEZ39614.1 - 2.7e-29 100.8 3.2 2.7e-29 100.8 2.2 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEZ39614.1 - 0.0017 18.2 0.2 0.036 14.0 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ39614.1 - 0.0054 17.2 0.0 0.032 14.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 KEZ39615.1 - 9.6e-11 41.1 7.8 0.0012 18.5 0.1 5.2 4 1 1 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KEZ39615.1 - 0.078 11.2 0.0 0.14 10.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain RNA_pol_3_Rpc31 PF11705.3 KEZ39616.1 - 0.011 15.6 5.3 0.028 14.3 3.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_E_B PF04042.11 KEZ39617.1 - 3.3e-52 176.7 0.0 4.5e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Elong-fact-P_C PF09285.6 KEZ39617.1 - 0.0067 15.7 0.5 0.045 13.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor P, C-terminal PALP PF00291.20 KEZ39618.1 - 6.7e-57 193.0 0.0 9.2e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CENP-S PF15630.1 KEZ39620.1 - 1.1e-30 105.6 0.2 1.7e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 KEZ39620.1 - 0.00023 20.5 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KEZ39620.1 - 0.00043 19.9 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 KEZ39620.1 - 0.013 15.2 0.1 0.017 14.9 0.1 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF956 PF06115.6 KEZ39620.1 - 0.068 12.7 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF956) TAF PF02969.12 KEZ39620.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.10 KEZ39620.1 - 0.092 12.5 0.1 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AA_permease_2 PF13520.1 KEZ39621.1 - 4.9e-37 127.4 35.9 7.1e-37 126.9 24.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ39621.1 - 1.2e-13 50.2 28.9 1.2e-13 50.2 20.1 1.7 1 1 1 2 2 2 1 Amino acid permease Spore_permease PF03845.8 KEZ39621.1 - 0.0051 15.5 1.5 0.0051 15.5 1.0 3.0 3 1 0 3 3 3 2 Spore germination protein Ribosomal_L4 PF00573.17 KEZ39623.1 - 6.7e-41 139.7 0.1 9.6e-41 139.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KEZ39623.1 - 1.2e-26 92.4 3.4 2.5e-26 91.3 2.4 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.16 KEZ39624.1 - 1.6e-13 50.3 0.0 7.8e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Lipase_3 PF01764.20 KEZ39626.1 - 2.9e-31 107.9 0.0 5.1e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KEZ39626.1 - 3.4e-12 45.9 0.0 6.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Cutinase PF01083.17 KEZ39626.1 - 0.00011 21.9 0.3 0.00036 20.3 0.2 1.9 1 1 0 1 1 1 1 Cutinase DUF2974 PF11187.3 KEZ39626.1 - 0.037 13.3 0.1 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LRR_8 PF13855.1 KEZ39627.1 - 4.2e-06 26.4 4.5 0.063 13.0 0.0 4.5 4 1 1 5 5 5 2 Leucine rich repeat DUF2890 PF11081.3 KEZ39627.1 - 0.00062 19.8 3.4 0.00097 19.2 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) LRR_4 PF12799.2 KEZ39627.1 - 0.0012 18.3 2.4 8.2 6.1 0.0 4.7 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEZ39627.1 - 0.0016 18.2 8.8 9.7 6.6 0.0 6.5 6 0 0 6 6 6 1 Leucine Rich repeat Myc_N PF01056.13 KEZ39627.1 - 0.0032 16.6 5.0 0.0049 16.0 3.5 1.3 1 0 0 1 1 1 1 Myc amino-terminal region LRR_7 PF13504.1 KEZ39627.1 - 0.23 11.8 5.1 1.5e+02 3.3 0.0 6.2 7 0 0 7 7 7 0 Leucine rich repeat Nop14 PF04147.7 KEZ39627.1 - 0.34 8.7 11.7 0.5 8.2 8.1 1.2 1 0 0 1 1 1 0 Nop14-like family alpha-hel2 PF14456.1 KEZ39627.1 - 0.42 9.3 4.2 0.87 8.2 2.9 1.5 1 0 0 1 1 1 0 Alpha-helical domain 2 LRR_1 PF00560.28 KEZ39627.1 - 0.83 9.9 7.1 11 6.4 0.0 5.6 9 0 0 9 9 9 0 Leucine Rich Repeat SNF2_N PF00176.18 KEZ39628.1 - 1.5e-60 204.5 0.0 2.6e-60 203.7 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ39628.1 - 8.9e-11 41.5 0.0 2.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ39628.1 - 1.1e-06 28.5 0.1 3.3e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KEZ39628.1 - 9e-06 25.2 13.5 9e-06 25.2 9.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ39628.1 - 1.5e-05 24.5 11.9 1.5e-05 24.5 8.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ39628.1 - 4.6e-05 23.3 13.4 4.6e-05 23.3 9.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ39628.1 - 0.0035 17.1 13.3 0.0035 17.1 9.2 2.3 2 0 0 2 2 2 1 Ring finger domain AAA_34 PF13872.1 KEZ39628.1 - 0.074 11.8 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.3 KEZ39628.1 - 0.096 12.2 5.8 0.3 10.6 4.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.1 KEZ39628.1 - 1.2 8.7 12.6 2 7.9 3.5 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.1 KEZ39628.1 - 9.7 6.0 24.4 0.32 10.7 9.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Tim17 PF02466.14 KEZ39629.1 - 6.5e-47 158.7 9.9 8.2e-47 158.4 6.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KEZ39629.1 - 0.0055 16.6 0.5 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF543) Gly-zipper_Omp PF13488.1 KEZ39629.1 - 0.037 13.6 2.2 0.037 13.6 1.5 2.7 4 0 0 4 4 4 0 Glycine zipper SDH_alpha PF03313.10 KEZ39629.1 - 0.75 8.7 5.1 0.12 11.3 1.1 1.5 2 0 0 2 2 2 0 Serine dehydratase alpha chain Gly-zipper_OmpA PF13436.1 KEZ39629.1 - 6.7 6.3 13.9 2.8 7.6 3.5 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain AMPKBI PF04739.10 KEZ39630.1 - 3.9e-28 97.2 0.6 1.6e-27 95.3 0.4 2.0 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain Macoilin PF09726.4 KEZ39630.1 - 1.4 7.1 11.6 2.1 6.5 8.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Ndc1_Nup PF09531.5 KEZ39630.1 - 3.3 6.0 9.7 4.6 5.5 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EPL1 PF10513.4 KEZ39631.1 - 4.7e-28 98.4 2.9 4.7e-28 98.4 2.0 2.5 3 1 0 3 3 3 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 KEZ39632.1 - 1.1e-19 68.1 12.4 9.1e-08 30.8 0.8 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KEZ39632.1 - 1.1e-16 60.7 4.7 1.5e-12 47.4 0.7 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEZ39632.1 - 4.7e-14 50.9 7.7 5.7e-07 28.6 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KEZ39632.1 - 3.2e-13 48.3 5.1 0.00012 21.7 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KEZ39632.1 - 1.2e-12 47.2 11.4 4.1e-06 26.3 1.1 3.6 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KEZ39632.1 - 1.2e-06 28.1 6.1 0.01 15.5 0.5 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEZ39632.1 - 8.9e-05 22.4 0.1 0.00018 21.5 0.1 1.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KEZ39632.1 - 0.0058 16.5 0.0 0.16 11.8 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain VCBS PF13517.1 KEZ39632.1 - 0.15 12.4 2.6 6.2 7.2 0.3 2.4 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S9 PF00380.14 KEZ39634.1 - 2.6e-36 124.5 0.2 4e-36 123.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 KEZ39635.1 - 2.1e-39 133.4 0.1 3.7e-39 132.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KEZ39635.1 - 5.2e-16 58.4 0.0 1.9e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEZ39635.1 - 4.2e-11 42.5 0.0 1.7e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEZ39635.1 - 3.5e-06 27.4 0.0 7.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEZ39635.1 - 5.3e-06 26.5 0.0 2.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ39635.1 - 4.5e-05 23.5 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Metallophos PF00149.23 KEZ39636.1 - 4.4e-39 133.9 0.0 6.6e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 KEZ39636.1 - 7.9e-31 105.9 0.3 2.4e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 KEZ39636.1 - 5.1e-28 96.5 10.4 3.3e-17 61.8 1.1 2.4 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KEZ39636.1 - 1.9e-18 65.2 5.2 3.4e-07 29.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ39636.1 - 1.3e-15 55.9 3.0 2.8e-05 23.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ39636.1 - 1.4e-06 28.0 1.5 0.0052 16.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ39636.1 - 7.5e-06 25.7 0.0 0.07 12.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ39636.1 - 1.5e-05 25.4 0.2 0.37 11.5 0.0 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ39636.1 - 0.00017 21.1 2.3 0.052 13.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ39636.1 - 0.00091 19.6 0.0 1 10.1 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ39636.1 - 0.011 16.1 0.1 0.49 10.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ39636.1 - 0.017 15.4 0.4 0.99 9.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ39636.1 - 0.017 15.0 0.1 1.9 8.4 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ39636.1 - 0.033 13.2 0.1 1.8 7.5 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Spt4 PF06093.8 KEZ39637.1 - 4e-33 113.1 0.1 5e-33 112.8 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 KEZ39637.1 - 0.16 11.7 0.7 0.43 10.4 0.1 1.9 1 1 1 2 2 2 0 Coronavirus gene 5 protein Cys_rich_CPXG PF14255.1 KEZ39637.1 - 0.37 10.6 3.8 16 5.4 0.0 2.6 2 1 0 2 2 2 0 Cysteine-rich CPXCG Kin17_mid PF10357.4 KEZ39638.1 - 7.1e-48 161.4 1.2 7.1e-48 161.4 0.9 2.8 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KEZ39638.1 - 0.0033 17.5 4.7 0.0073 16.4 3.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEZ39638.1 - 0.008 16.2 3.7 0.016 15.2 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KEZ39638.1 - 0.033 14.2 0.4 0.033 14.2 0.3 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SlyX PF04102.7 KEZ39639.1 - 0.15 12.4 1.8 0.36 11.2 1.2 1.7 1 0 0 1 1 1 0 SlyX PBP PF01161.15 KEZ39640.1 - 8.8e-18 64.5 0.1 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein USP7_ICP0_bdg PF12436.3 KEZ39641.1 - 7e-75 251.4 0.0 2.6e-73 246.3 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KEZ39641.1 - 3.5e-72 242.2 1.8 3.5e-72 242.2 1.3 3.8 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 KEZ39641.1 - 5.9e-56 189.5 2.1 5.9e-56 189.5 1.5 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ39641.1 - 6.6e-29 101.2 1.6 9.1e-29 100.8 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KEZ39641.1 - 2.4e-12 47.1 1.8 2.2e-11 44.0 0.0 3.0 3 0 0 3 3 3 1 MATH domain YukD PF08817.5 KEZ39641.1 - 0.035 14.6 0.0 5.4 7.6 0.0 3.0 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.4 KEZ39642.1 - 1.5e-43 148.1 0.1 2.6e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEZ39642.1 - 4.1e-09 36.1 0.0 1.6e-05 24.5 0.0 2.8 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEZ39642.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Baculo_IE-1 PF05290.6 KEZ39642.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Septin PF00735.13 KEZ39643.1 - 7.3e-117 389.3 0.3 1.1e-116 388.8 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KEZ39643.1 - 6e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEZ39643.1 - 2.8e-06 26.9 0.6 5.7e-05 22.6 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEZ39643.1 - 1.2e-05 24.5 0.0 3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KEZ39643.1 - 0.0024 18.3 0.1 0.0081 16.6 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 KEZ39643.1 - 0.0033 17.0 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEZ39643.1 - 0.0036 17.4 0.3 0.015 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 KEZ39643.1 - 0.0065 15.5 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KEZ39643.1 - 0.0069 15.8 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 KEZ39643.1 - 0.0071 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 KEZ39643.1 - 0.012 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 KEZ39643.1 - 0.017 14.5 0.6 0.054 12.8 0.4 1.9 2 1 0 2 2 2 0 Ras family NACHT PF05729.7 KEZ39643.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KEZ39643.1 - 0.047 13.9 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 KEZ39643.1 - 0.049 12.5 0.3 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 KEZ39643.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.4 KEZ39643.1 - 0.081 12.4 0.7 2.8 7.4 0.2 2.7 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KEZ39643.1 - 0.089 12.5 7.2 0.71 9.6 0.1 3.0 2 1 1 3 3 3 0 Dynamin family ArgK PF03308.11 KEZ39643.1 - 0.11 11.3 2.5 0.89 8.2 0.0 2.9 3 0 0 3 3 3 0 ArgK protein DUF2968 PF11180.3 KEZ39643.1 - 0.11 11.8 6.8 0.31 10.4 4.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) RNA_helicase PF00910.17 KEZ39643.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Ribosomal_L6e PF01159.14 KEZ39643.1 - 0.13 12.5 5.0 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_16 PF13191.1 KEZ39643.1 - 0.13 12.1 2.8 0.37 10.7 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 KEZ39643.1 - 0.18 10.7 1.9 0.25 10.3 1.3 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Myc-LZ PF02344.10 KEZ39643.1 - 2.9 7.6 11.7 1.6 8.3 3.2 2.9 2 1 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.27 KEZ39644.1 - 6.7e-49 162.1 32.7 3.1e-12 45.8 0.1 11.8 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 KEZ39644.1 - 2.4e-26 91.8 0.0 3.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KEZ39644.1 - 1.4e-07 31.4 2.5 0.018 14.7 0.0 6.1 6 1 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KEZ39644.1 - 3.4e-07 28.5 0.0 0.0001 20.3 0.0 2.4 2 1 0 2 2 2 2 IKI3 family Nup160 PF11715.3 KEZ39644.1 - 1.7e-05 23.1 5.6 0.17 9.9 0.0 4.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KEZ39644.1 - 0.0004 19.5 0.1 1.1 8.3 0.0 4.0 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal DUF4243 PF14027.1 KEZ39645.1 - 2.5e-68 230.9 1.1 3.3e-68 230.5 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAP PF00956.13 KEZ39646.1 - 1.2e-46 158.8 0.4 1.6e-46 158.4 0.3 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) BUD22 PF09073.5 KEZ39646.1 - 0.0079 15.3 1.6 0.011 14.8 1.1 1.2 1 0 0 1 1 1 1 BUD22 PBP1_TM PF14812.1 KEZ39646.1 - 0.018 15.3 4.5 6 7.2 2.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tox-GHH PF15636.1 KEZ39646.1 - 0.45 10.1 3.6 0.28 10.8 0.9 1.9 1 1 1 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF2457 PF10446.4 KEZ39646.1 - 9.3 4.8 15.0 14 4.2 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Baculo_PEP_C PF04513.7 KEZ39647.1 - 1.6 8.5 8.9 4.8 7.0 3.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 KEZ39648.1 - 3.2e-63 213.3 0.0 3.8e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39648.1 - 1.7e-29 102.6 0.0 2.3e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39648.1 - 0.034 13.1 0.0 0.065 12.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like FAT PF02259.18 KEZ39649.1 - 5e-74 249.3 1.8 1.3e-73 248.0 1.3 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KEZ39649.1 - 6.6e-26 91.2 0.6 1.8e-25 89.7 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KEZ39649.1 - 6.1e-11 41.5 0.5 1.7e-10 40.1 0.3 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 KEZ39649.1 - 0.11 12.4 2.6 3.7 7.6 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ39649.1 - 0.91 9.4 4.2 21 5.1 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.8 KEZ39649.1 - 7 6.4 26.8 15 5.3 18.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIG2 PF06094.7 KEZ39650.1 - 9e-19 67.8 0.1 1.3e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family DUF3433 PF11915.3 KEZ39651.1 - 4.6e-39 132.4 4.1 7.8e-20 70.8 0.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) SMAP PF15477.1 KEZ39652.1 - 0.091 13.0 3.7 1.9 8.8 0.6 3.1 2 0 0 2 2 2 0 Small acidic protein family Fungal_trans PF04082.13 KEZ39653.1 - 8.1e-37 126.5 0.7 9.6e-37 126.2 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ39653.1 - 8.4e-08 32.0 9.6 1.5e-07 31.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin-6_N PF09177.6 KEZ39654.1 - 2.9e-24 85.3 0.5 8.9e-24 83.7 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KEZ39654.1 - 4.5e-12 45.4 4.6 4.5e-12 45.4 3.2 2.5 3 0 0 3 3 3 1 SNARE domain FlaC_arch PF05377.6 KEZ39654.1 - 0.0035 17.2 0.1 8.8 6.3 0.0 3.2 3 0 0 3 3 3 2 Flagella accessory protein C (FlaC) MscS_porin PF12795.2 KEZ39654.1 - 0.0051 16.1 1.7 0.0051 16.1 1.1 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain NPV_P10 PF05531.7 KEZ39654.1 - 0.011 15.9 0.9 5.3 7.3 0.0 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KEZ39654.1 - 0.019 14.1 1.7 0.046 12.9 0.6 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 KEZ39654.1 - 0.057 12.8 4.2 2.3 7.6 0.7 2.5 2 1 0 2 2 2 0 Intermediate filament protein MbeD_MobD PF04899.7 KEZ39654.1 - 0.1 12.4 2.4 1.5 8.8 0.1 2.6 2 1 0 2 2 2 0 MbeD/MobD like THOC7 PF05615.8 KEZ39654.1 - 0.11 12.7 1.1 0.88 9.8 0.1 2.4 2 1 0 2 2 2 0 Tho complex subunit 7 Enkurin PF13864.1 KEZ39654.1 - 0.12 12.5 1.7 1.5 9.1 0.2 2.7 3 0 0 3 3 3 0 Calmodulin-binding CorA PF01544.13 KEZ39654.1 - 0.56 9.1 4.5 6 5.8 0.1 3.0 3 1 0 3 3 3 0 CorA-like Mg2+ transporter protein FliD_N PF02465.13 KEZ39654.1 - 0.67 10.3 4.5 20 5.6 0.3 3.1 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.4 KEZ39654.1 - 1.6 8.5 5.3 5.4 6.8 0.3 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACT_7 PF13840.1 KEZ39655.1 - 1.4e-20 72.5 0.9 4.7e-16 58.0 0.1 2.5 2 0 0 2 2 2 2 ACT domain HC2 PF07382.6 KEZ39656.1 - 0.11 12.3 91.2 0.035 13.9 21.2 4.9 1 1 3 4 4 4 0 Histone H1-like nucleoprotein HC2 Porin_3 PF01459.17 KEZ39657.1 - 1.2e-82 277.3 1.0 1.4e-82 277.1 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 KEZ39658.1 - 5.7e-61 205.4 0.0 8e-61 204.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KEZ39658.1 - 2e-24 86.5 0.5 3.6e-24 85.6 0.4 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KEZ39658.1 - 0.00011 22.1 0.1 0.001 18.9 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 KEZ39658.1 - 0.0072 17.1 0.2 0.046 14.5 0.0 2.4 2 1 1 3 3 3 1 AAA domain APS_kinase PF01583.15 KEZ39658.1 - 0.13 11.9 0.0 8.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase UCH_1 PF13423.1 KEZ39659.1 - 6.7e-71 239.1 0.0 1.3e-70 238.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 KEZ39659.1 - 7.4e-15 54.7 0.0 1.7e-14 53.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.16 KEZ39660.1 - 1.3e-21 76.1 0.0 1.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Actin PF00022.14 KEZ39661.1 - 1.5e-159 530.6 0.0 1.7e-159 530.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KEZ39661.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RF-1 PF00472.15 KEZ39662.1 - 3.6e-26 91.1 2.0 6.5e-26 90.3 1.4 1.3 1 0 0 1 1 1 1 RF-1 domain DUF3317 PF11779.3 KEZ39663.1 - 2e-16 59.1 7.6 2.5e-16 58.8 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) WD40 PF00400.27 KEZ39664.1 - 3.4e-55 182.0 10.4 5.1e-08 32.5 0.0 10.4 11 0 0 11 11 11 9 WD domain, G-beta repeat MucBP PF06458.7 KEZ39664.1 - 0.14 12.7 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 MucBP domain Mito_carr PF00153.22 KEZ39665.1 - 3.8e-60 199.5 3.2 8.7e-22 76.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 KEZ39666.1 - 0.0063 16.7 4.3 0.0063 16.7 3.0 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ39666.1 - 1.8 9.0 5.9 0.84 10.1 2.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ39666.1 - 8.9 6.8 10.0 3.7 8.0 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Urm1 PF09138.6 KEZ39667.1 - 1.7e-35 121.0 0.0 1.9e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KEZ39667.1 - 1.5e-05 25.3 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ThiS family RRM_1 PF00076.17 KEZ39668.1 - 7.5e-34 115.2 0.0 6.5e-17 60.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ39668.1 - 2.4e-18 65.8 0.0 3.1e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ39668.1 - 1.2e-16 60.2 0.0 1.7e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KEZ39668.1 - 0.0093 15.4 0.3 0.95 9.0 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KEZ39668.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MIF4G_like PF09088.6 KEZ39669.1 - 5.8e-82 273.7 0.0 3.4e-81 271.2 0.0 2.0 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 KEZ39669.1 - 1.1e-47 162.4 0.0 1.9e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KEZ39669.1 - 0.00064 19.1 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain Pkinase PF00069.20 KEZ39670.1 - 2e-54 184.4 0.0 8.4e-50 169.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39670.1 - 6.5e-17 61.4 0.0 9.8e-15 54.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39670.1 - 6.8e-07 28.5 0.0 1.6e-06 27.2 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KEZ39670.1 - 0.00073 19.3 0.0 0.0038 16.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ39670.1 - 0.04 13.4 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF410 PF04190.8 KEZ39671.1 - 1.9e-54 184.9 0.0 2.2e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) tRNA-synt_1 PF00133.17 KEZ39672.1 - 4.1e-52 177.0 0.3 3e-10 38.7 0.0 6.1 3 1 3 6 6 6 6 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KEZ39672.1 - 3.1e-40 137.4 0.0 8e-40 136.1 0.0 1.7 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KEZ39672.1 - 1.5e-32 112.7 0.0 1.5e-24 86.3 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEZ39672.1 - 1.2e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KEZ39672.1 - 0.00043 19.5 0.0 0.27 10.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KEZ39672.1 - 0.0017 17.2 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 KEZ39672.1 - 0.21 10.1 0.3 13 4.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain ORC6 PF05460.8 KEZ39673.1 - 0.74 8.8 12.1 1 8.4 8.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pneumo_att_G PF05539.6 KEZ39673.1 - 4.5 6.5 12.5 5.8 6.1 8.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PQ-loop PF04193.9 KEZ39674.1 - 3.3e-19 68.1 3.7 1.3e-13 50.3 1.2 2.5 2 0 0 2 2 2 2 PQ loop repeat SMI1_KNR4 PF09346.5 KEZ39675.1 - 6e-34 116.8 0.0 1e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pkinase PF00069.20 KEZ39676.1 - 2.9e-70 236.3 0.0 4e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39676.1 - 1.7e-50 171.5 0.0 2.7e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39676.1 - 0.00023 20.2 0.0 0.0013 17.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF2336 PF10098.4 KEZ39676.1 - 0.015 14.5 4.0 0.13 11.5 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2336) Transglut_core PF01841.14 KEZ39677.1 - 5.8e-11 42.6 0.1 1.4e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KEZ39677.1 - 7.3e-09 34.9 0.3 1.9e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ39677.1 - 3.8e-06 26.1 1.4 1.7e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KEZ39677.1 - 0.0005 19.6 0.2 0.0005 19.6 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain CCDC32 PF14989.1 KEZ39677.1 - 0.052 13.3 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing 32 WD40 PF00400.27 KEZ39678.1 - 1.4e-28 97.6 13.1 9.5e-09 34.8 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 KEZ39678.1 - 1.4e-19 69.8 0.1 2.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain IKI3 PF04762.7 KEZ39678.1 - 0.092 10.5 0.1 0.74 7.5 0.0 1.9 2 0 0 2 2 2 0 IKI3 family Sec8_exocyst PF04048.9 KEZ39679.1 - 1e-49 167.8 3.2 2.7e-49 166.4 2.2 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KEZ39679.1 - 1.2e-09 37.5 3.4 2.5e-09 36.4 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 KEZ39679.1 - 0.00089 19.0 0.4 0.0024 17.6 0.3 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Occludin_ELL PF07303.8 KEZ39679.1 - 0.18 12.5 2.8 0.43 11.3 0.9 2.5 1 1 0 1 1 1 0 Occludin homology domain Phage_GP20 PF06810.6 KEZ39679.1 - 0.24 10.8 5.4 0.075 12.4 0.8 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 4HB_MCP_1 PF12729.2 KEZ39679.1 - 1.1 8.5 5.6 0.57 9.5 0.6 2.9 3 1 0 4 4 4 0 Four helix bundle sensory module for signal transduction UPF0220 PF05255.6 KEZ39680.1 - 8.4e-61 204.0 2.4 9.4e-61 203.8 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DNA_pol_A_exo1 PF01612.15 KEZ39681.1 - 1.8e-19 69.8 0.0 3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.27 KEZ39682.1 - 1.5e-27 94.4 5.3 1.9e-06 27.5 0.6 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ PF01011.16 KEZ39682.1 - 0.038 13.5 0.3 3.5 7.3 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.1 KEZ39682.1 - 1.5 9.2 8.8 3.5 8.0 0.8 4.7 4 1 1 5 5 5 0 PQQ-like domain Glyco_transf_15 PF01793.11 KEZ39683.1 - 4.4e-135 449.9 5.6 5.1e-135 449.6 3.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 KEZ39684.1 - 2.7e-68 230.6 0.3 2.7e-68 230.6 0.2 1.8 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KEZ39684.1 - 2.6e-06 25.8 0.0 6.5e-06 24.5 0.0 1.6 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 RNA_pol_L_2 PF13656.1 KEZ39685.1 - 3e-23 81.0 0.1 3.8e-23 80.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEZ39685.1 - 1.6e-07 30.3 0.0 2.7e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 KEZ39685.1 - 0.018 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal SIR2_2 PF13289.1 KEZ39685.1 - 0.073 12.9 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain Asparaginase PF00710.15 KEZ39686.1 - 8e-101 337.0 0.0 1e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KEZ39686.1 - 3.9e-13 49.5 0.1 7.5e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ39686.1 - 6.3e-13 47.8 0.2 1.6e-06 27.6 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEZ39686.1 - 1.3e-10 41.4 0.7 3.1e-05 24.3 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ39686.1 - 8.3e-09 35.4 0.3 2.3e-06 27.6 0.2 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ39686.1 - 4.1e-06 26.5 0.2 0.0049 16.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat ATP-synt_ab PF00006.20 KEZ39687.1 - 3.2e-112 373.2 0.0 4.8e-112 372.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 KEZ39687.1 - 1.2e-15 57.4 1.6 2.7e-15 56.3 1.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 KEZ39687.1 - 5.1e-15 55.9 0.1 1.1e-14 54.8 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain NB-ARC PF00931.17 KEZ39687.1 - 0.044 12.6 0.1 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Metallophos PF00149.23 KEZ39688.1 - 4.8e-14 52.2 0.3 7.2e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEZ39688.1 - 0.00011 22.0 0.5 0.00021 21.1 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TruB_N PF01509.13 KEZ39690.1 - 5e-44 150.0 0.0 1e-43 149.0 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DUF2951 PF11166.3 KEZ39690.1 - 0.042 13.7 2.8 0.078 12.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) EXOSC1 PF10447.4 KEZ39691.1 - 2.6e-25 88.1 1.2 6e-25 87.0 0.6 1.7 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KEZ39691.1 - 3.1e-10 39.1 0.6 6.1e-10 38.2 0.4 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 KEZ39691.1 - 0.0096 15.9 0.3 0.073 13.1 0.2 2.1 1 1 0 1 1 1 1 S1 RNA binding domain SBP_bac_6 PF13343.1 KEZ39691.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein ERG2_Sigma1R PF04622.7 KEZ39692.1 - 7.4e-98 326.0 0.2 8.4e-98 325.9 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Fcf1 PF04900.7 KEZ39693.1 - 3.5e-36 123.3 0.6 8.4e-36 122.1 0.0 1.9 2 1 0 2 2 2 1 Fcf1 ABC_tran PF00005.22 KEZ39694.1 - 9.8e-49 165.1 0.0 8.9e-27 94.0 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 KEZ39694.1 - 1.6e-45 155.6 38.4 5.3e-27 94.9 14.5 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_29 PF13555.1 KEZ39694.1 - 9.6e-07 28.2 0.1 0.008 15.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KEZ39694.1 - 6.7e-06 26.2 0.1 1.4 8.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain SMC_N PF02463.14 KEZ39694.1 - 6.8e-06 25.4 1.1 1.2 8.3 0.0 3.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KEZ39694.1 - 9e-06 25.6 0.6 0.18 11.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 KEZ39694.1 - 3.4e-05 23.9 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 KEZ39694.1 - 5.2e-05 23.7 1.2 0.12 12.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 KEZ39694.1 - 7.2e-05 21.9 0.1 0.039 13.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 KEZ39694.1 - 7.2e-05 22.0 0.3 0.05 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ39694.1 - 0.00016 22.4 2.3 0.084 13.6 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEZ39694.1 - 0.00033 20.1 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 KEZ39694.1 - 0.00039 20.7 0.3 0.76 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEZ39694.1 - 0.0013 18.3 0.5 1.7 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEZ39694.1 - 0.002 17.5 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KEZ39694.1 - 0.0029 17.4 4.7 0.13 12.1 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KEZ39694.1 - 0.0031 16.9 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KEZ39694.1 - 0.0034 17.5 0.1 3.3 7.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.4 KEZ39694.1 - 0.0088 14.7 0.6 0.53 8.8 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 KEZ39694.1 - 0.013 15.3 3.9 0.084 12.6 0.3 2.6 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 KEZ39694.1 - 0.024 13.4 1.6 0.99 8.1 0.2 2.4 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 KEZ39694.1 - 0.029 14.0 1.5 2.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEZ39694.1 - 0.036 14.3 0.9 2.8 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain U79_P34 PF03064.11 KEZ39694.1 - 0.071 12.6 2.3 0.2 11.1 1.6 1.7 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNA_helicase PF00910.17 KEZ39694.1 - 0.14 12.3 0.2 39 4.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase T2SE PF00437.15 KEZ39694.1 - 0.14 11.0 0.3 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 KEZ39694.1 - 0.22 11.0 1.3 11 5.4 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KEZ39694.1 - 0.24 11.3 1.5 0.77 9.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 KEZ39694.1 - 0.49 9.3 0.0 11 4.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Spc24 PF08286.6 KEZ39695.1 - 0.087 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1762 PF08574.5 KEZ39696.1 - 0.16 12.4 2.5 0.53 10.7 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1762) Elf1 PF05129.8 KEZ39696.1 - 0.49 10.1 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like GDA1_CD39 PF01150.12 KEZ39697.1 - 3.9e-99 332.0 0.0 4.8e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KEZ39697.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family AAA_3 PF07726.6 KEZ39698.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UreE_C PF05194.7 KEZ39698.1 - 0.082 13.0 4.6 0.22 11.6 3.2 1.8 1 1 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Ras PF00071.17 KEZ39699.1 - 1.7e-45 154.2 0.1 2.1e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KEZ39699.1 - 7.5e-09 35.0 0.0 8.7e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KEZ39699.1 - 2.1e-08 34.6 0.0 3.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEZ39699.1 - 1.7e-05 24.3 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEZ39699.1 - 0.0072 15.4 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region UAA PF08449.6 KEZ39700.1 - 1.9e-06 27.0 15.1 2.5e-05 23.3 9.1 2.1 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 KEZ39700.1 - 6.1e-06 26.2 5.6 6.1e-06 26.2 3.9 2.8 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 KEZ39700.1 - 0.00025 20.0 10.0 0.00053 18.9 6.9 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 KEZ39700.1 - 0.0003 20.9 4.3 0.0003 20.9 3.0 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KEZ39700.1 - 0.034 13.7 28.4 0.036 13.7 3.9 3.0 3 0 0 3 3 3 0 Triose-phosphate Transporter family Brr6_like_C_C PF10104.4 KEZ39700.1 - 0.48 9.9 2.3 0.69 9.4 0.0 2.5 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain WD40 PF00400.27 KEZ39701.1 - 3.9e-23 80.4 7.9 1.3e-05 24.9 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Spb1_C PF07780.7 KEZ39702.1 - 1.8e-79 266.2 25.7 1.8e-79 266.2 17.8 3.8 3 1 1 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 KEZ39702.1 - 3.8e-56 188.9 11.1 3.8e-56 188.9 7.7 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KEZ39702.1 - 2e-55 187.5 0.0 4.8e-55 186.3 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DHHW PF14286.1 KEZ39702.1 - 3.4 6.8 16.4 7.7 5.7 6.5 2.5 2 0 0 2 2 2 0 DHHW protein Cupin_8 PF13621.1 KEZ39703.1 - 1.7e-63 214.4 0.0 2.2e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KEZ39703.1 - 1.2e-05 24.7 0.0 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KEZ39703.1 - 0.031 14.5 0.1 0.33 11.1 0.0 2.4 3 0 0 3 3 3 0 JmjC domain, hydroxylase CaMBD PF02888.11 KEZ39704.1 - 0.037 13.8 0.7 0.087 12.6 0.5 1.5 1 0 0 1 1 1 0 Calmodulin binding domain Macoilin PF09726.4 KEZ39704.1 - 0.13 10.5 12.6 0.15 10.3 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4202 PF13875.1 KEZ39705.1 - 9.4e-59 198.1 0.6 8.4e-58 195.0 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4202) N-SET PF11764.3 KEZ39707.1 - 2.5e-41 141.3 0.0 2.5e-41 141.3 0.0 2.6 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KEZ39707.1 - 6.8e-24 84.9 0.2 6.8e-24 84.9 0.1 4.1 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.3 KEZ39707.1 - 8.9e-23 79.3 0.4 2e-22 78.2 0.3 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Tropomyosin_1 PF12718.2 KEZ39709.1 - 3.5e-49 166.3 29.8 4.1e-49 166.1 20.6 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KEZ39709.1 - 2.8e-09 36.4 29.4 5.2e-06 25.7 11.2 2.3 1 1 1 2 2 2 2 Tropomyosin Cast PF10174.4 KEZ39709.1 - 4.8e-05 21.6 24.0 5.2e-05 21.5 16.7 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Mod_r PF07200.8 KEZ39709.1 - 6.2e-05 22.9 23.1 0.0016 18.4 9.4 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 KEZ39709.1 - 0.00068 19.3 28.0 0.048 13.4 6.5 2.2 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein ADIP PF11559.3 KEZ39709.1 - 0.00094 19.1 28.6 0.011 15.6 5.0 3.0 1 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KEZ39709.1 - 0.00097 18.4 1.8 0.18 10.9 0.4 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 KEZ39709.1 - 0.0011 16.8 28.5 0.0013 16.6 19.7 1.1 1 0 0 1 1 1 1 Myosin tail APG6 PF04111.7 KEZ39709.1 - 0.0011 18.0 16.7 0.0011 18.0 11.6 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 KEZ39709.1 - 0.0012 18.5 23.7 0.0098 15.6 9.1 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding GAS PF13851.1 KEZ39709.1 - 0.0013 18.0 28.5 0.014 14.5 12.3 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 KEZ39709.1 - 0.0019 18.1 28.6 0.1 12.5 10.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) IncA PF04156.9 KEZ39709.1 - 0.002 17.7 26.6 0.043 13.4 18.4 2.1 1 1 0 1 1 1 1 IncA protein ATG16 PF08614.6 KEZ39709.1 - 0.0022 17.8 27.7 0.085 12.6 5.4 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF745 PF05335.8 KEZ39709.1 - 0.0024 17.4 17.4 0.048 13.1 3.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.4 KEZ39709.1 - 0.0025 17.6 29.4 0.003 17.4 3.8 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 KEZ39709.1 - 0.0031 17.0 32.5 0.073 12.5 11.6 2.1 1 1 0 2 2 2 2 Ezrin/radixin/moesin family LPP PF04728.8 KEZ39709.1 - 0.0033 17.1 3.9 0.049 13.4 0.7 3.0 2 1 1 3 3 3 1 Lipoprotein leucine-zipper Spc7 PF08317.6 KEZ39709.1 - 0.0064 15.2 24.3 0.059 12.0 7.7 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Atg14 PF10186.4 KEZ39709.1 - 0.0087 15.0 21.7 0.0057 15.6 9.6 2.0 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Surfac_D-trimer PF09006.6 KEZ39709.1 - 0.0091 15.7 4.5 0.042 13.5 0.0 3.5 4 0 0 4 4 3 1 Lung surfactant protein D coiled-coil trimerisation NPV_P10 PF05531.7 KEZ39709.1 - 0.012 15.8 11.0 0.13 12.5 3.2 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.16 KEZ39709.1 - 0.013 15.4 27.5 1.3 9.0 0.7 4.7 2 2 2 4 4 4 0 bZIP transcription factor EzrA PF06160.7 KEZ39709.1 - 0.014 13.6 21.5 0.12 10.4 6.1 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 KEZ39709.1 - 0.014 15.5 20.0 0.68 10.0 7.6 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 KEZ39709.1 - 0.015 15.1 29.9 0.064 13.0 7.5 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 KEZ39709.1 - 0.016 15.2 16.4 0.35 10.9 2.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4482 PF14818.1 KEZ39709.1 - 0.023 15.3 5.1 0.023 15.3 3.5 2.8 1 1 0 2 2 1 0 Domain of unknown function (DUF4482) Syntaxin-6_N PF09177.6 KEZ39709.1 - 0.029 14.7 17.0 2.9 8.3 5.3 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.7 KEZ39709.1 - 0.032 13.9 17.4 0.039 13.7 3.2 2.6 1 1 1 2 2 2 0 Laminin Domain II PilJ PF13675.1 KEZ39709.1 - 0.034 14.4 11.1 0.73 10.1 3.3 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cep57_MT_bd PF06657.8 KEZ39709.1 - 0.058 13.3 18.5 0.14 12.1 1.6 3.4 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3450 PF11932.3 KEZ39709.1 - 0.062 12.5 22.0 0.25 10.5 5.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-Q PF13094.1 KEZ39709.1 - 0.087 12.8 30.5 0.42 10.6 14.2 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Mnd1 PF03962.10 KEZ39709.1 - 0.089 12.4 27.2 0.23 11.0 5.5 2.1 1 1 1 2 2 2 0 Mnd1 family DUF4140 PF13600.1 KEZ39709.1 - 0.097 13.1 20.7 0.47 10.9 2.5 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Lebercilin PF15619.1 KEZ39709.1 - 0.1 12.0 28.8 0.81 9.0 15.0 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HOOK PF05622.7 KEZ39709.1 - 0.11 10.3 23.6 0.16 9.7 16.4 1.4 1 0 0 1 1 1 0 HOOK protein WXG100 PF06013.7 KEZ39709.1 - 0.11 12.4 13.6 2 8.4 0.1 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG TBPIP PF07106.8 KEZ39709.1 - 0.11 11.9 24.5 1.1 8.8 6.8 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 KEZ39709.1 - 0.12 11.7 24.6 0.98 8.8 8.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein Fmp27_WPPW PF10359.4 KEZ39709.1 - 0.13 10.6 21.0 0.056 11.8 5.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.1 KEZ39709.1 - 0.17 10.3 20.8 0.37 9.2 14.4 1.5 1 1 0 1 1 1 0 AAA domain Vps5 PF09325.5 KEZ39709.1 - 0.17 11.1 21.3 0.014 14.6 7.5 2.4 1 1 2 3 3 3 0 Vps5 C terminal like FlaC_arch PF05377.6 KEZ39709.1 - 0.2 11.5 17.9 0.58 10.0 0.9 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) CCDC155 PF14662.1 KEZ39709.1 - 0.22 11.0 30.2 0.13 11.8 12.3 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 KLRAQ PF10205.4 KEZ39709.1 - 0.24 11.4 18.4 0.037 14.0 3.4 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Taxilin PF09728.4 KEZ39709.1 - 0.27 10.2 26.5 0.11 11.5 4.8 2.5 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF3584 PF12128.3 KEZ39709.1 - 0.3 8.3 24.1 0.42 7.8 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF904 PF06005.7 KEZ39709.1 - 0.34 11.2 37.2 3 8.1 3.0 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF3287 PF11690.3 KEZ39709.1 - 0.34 10.9 7.7 0.18 11.8 1.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) DUF869 PF05911.6 KEZ39709.1 - 0.37 8.9 22.2 2.2 6.3 15.4 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) WEMBL PF05701.6 KEZ39709.1 - 0.4 9.1 28.1 0.16 10.3 14.4 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Seryl_tRNA_N PF02403.17 KEZ39709.1 - 0.44 10.5 25.6 2.6 8.1 2.6 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Herpes_capsid PF06112.6 KEZ39709.1 - 0.49 10.4 3.4 0.16 11.9 0.4 1.7 2 0 0 2 2 1 0 Gammaherpesvirus capsid protein Cortex-I_coil PF09304.5 KEZ39709.1 - 0.49 10.4 27.0 4.2 7.4 0.7 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF4201 PF13870.1 KEZ39709.1 - 0.59 9.5 23.2 0.53 9.6 10.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HAP1_N PF04849.8 KEZ39709.1 - 0.59 9.0 26.3 12 4.7 18.2 3.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Striatin PF08232.7 KEZ39709.1 - 0.6 10.4 20.7 77 3.6 14.4 2.1 1 1 0 1 1 1 0 Striatin family MAD PF05557.8 KEZ39709.1 - 0.62 8.0 24.6 1.7 6.6 8.8 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF972 PF06156.8 KEZ39709.1 - 0.66 10.3 23.8 0.26 11.6 4.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KEZ39709.1 - 0.78 9.5 13.8 5 6.9 0.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 KEZ39709.1 - 0.78 9.7 24.6 2.6 8.1 11.1 3.2 1 1 1 2 2 2 0 DivIVA protein Cep57_CLD_2 PF14197.1 KEZ39709.1 - 0.81 9.6 28.4 2.6 8.0 5.6 3.6 1 1 2 3 3 2 0 Centrosome localisation domain of PPC89 Uds1 PF15456.1 KEZ39709.1 - 0.91 9.5 21.5 2.7 8.0 1.9 2.4 1 1 1 2 2 2 0 Up-regulated During Septation Nup54 PF13874.1 KEZ39709.1 - 1.4 8.5 21.6 1.7 8.2 2.9 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.4 KEZ39709.1 - 1.5 8.7 25.1 0.9 9.5 10.4 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2514 PF10721.4 KEZ39709.1 - 1.6 8.3 14.1 0.22 11.1 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Transketolase_N PF00456.16 KEZ39709.1 - 2 7.1 5.9 2.6 6.7 4.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF730 PF05325.6 KEZ39709.1 - 2.2 8.1 15.0 0.79 9.5 1.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF730) Syntaxin_2 PF14523.1 KEZ39709.1 - 2.3 8.3 15.0 0.34 10.9 3.2 2.2 1 1 1 2 2 2 0 Syntaxin-like protein DUF812 PF05667.6 KEZ39709.1 - 2.3 6.6 24.0 6.7 5.0 16.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) HD_3 PF13023.1 KEZ39709.1 - 2.4 7.8 11.7 0.6 9.8 5.3 1.8 1 1 1 2 2 2 0 HD domain FliD_N PF02465.13 KEZ39709.1 - 2.7 8.4 10.7 1.3 9.3 0.3 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus BssS PF13991.1 KEZ39709.1 - 2.8 7.7 4.5 1.7 8.4 0.3 2.4 2 1 0 2 2 2 0 BssS protein family Prefoldin PF02996.12 KEZ39709.1 - 2.9 7.5 27.0 1.4 8.5 1.4 4.0 1 1 3 4 4 4 0 Prefoldin subunit MbeD_MobD PF04899.7 KEZ39709.1 - 3.1 7.7 12.6 4.1 7.3 0.3 3.1 2 2 2 4 4 3 0 MbeD/MobD like DUF724 PF05266.9 KEZ39709.1 - 3.3 7.2 25.4 3.3 7.2 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.7 KEZ39709.1 - 4.5 7.7 19.4 6.6 7.1 1.5 3.5 2 2 2 4 4 4 0 SlyX PspA_IM30 PF04012.7 KEZ39709.1 - 4.5 6.5 24.4 5.4 6.3 6.6 2.7 1 1 1 3 3 3 0 PspA/IM30 family Rootletin PF15035.1 KEZ39709.1 - 4.8 7.1 25.7 20 5.1 17.8 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1515 PF07439.6 KEZ39709.1 - 5.4 6.8 7.8 8.8 6.1 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DUF641 PF04859.7 KEZ39709.1 - 6.1 6.6 18.6 0.54 10.0 2.4 2.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 KEZ39709.1 - 6.1 6.2 27.3 4.3 6.7 9.9 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4407 PF14362.1 KEZ39709.1 - 6.2 5.6 20.3 3.9 6.3 9.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) rRNA_proc-arch PF13234.1 KEZ39709.1 - 6.3 5.8 15.1 0.1 11.7 1.6 2.7 1 1 1 2 2 2 0 rRNA-processing arch domain CDC37_N PF03234.9 KEZ39709.1 - 6.4 7.0 21.9 50 4.1 15.0 2.2 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF342 PF03961.8 KEZ39709.1 - 7.3 4.8 24.4 0.62 8.4 6.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMCO5 PF14992.1 KEZ39709.1 - 8.2 5.4 25.2 12 4.8 5.1 2.2 1 1 1 2 2 2 0 TMCO5 family Nop25 PF09805.4 KEZ39710.1 - 4.7e-34 117.3 15.6 4.7e-34 117.3 10.8 2.5 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF2229 PF09989.4 KEZ39710.1 - 0.11 11.9 1.6 0.2 11.0 1.1 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) RseA_C PF03873.8 KEZ39710.1 - 0.7 9.8 5.4 0.88 9.4 1.0 2.9 3 1 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain EIIBC-GUT_N PF03612.9 KEZ39710.1 - 1.9 8.0 11.4 3.6 7.1 0.9 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2937 PF11157.3 KEZ39710.1 - 2.4 7.4 5.8 3.6 6.8 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) ATP-synt_S1 PF05827.7 KEZ39711.1 - 4.3e-36 124.6 0.8 2.4e-35 122.2 0.5 1.9 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Trm112p PF03966.11 KEZ39712.1 - 1.4e-15 57.3 0.1 1.9e-15 56.9 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Pro_isomerase PF00160.16 KEZ39713.1 - 2e-47 161.2 0.5 2.3e-47 161.0 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1942 PF09167.6 KEZ39713.1 - 0.07 12.8 0.1 0.2 11.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1942) Ribosomal_S13 PF00416.17 KEZ39714.1 - 4e-20 72.2 0.0 4.4e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_M19 PF01244.16 KEZ39715.1 - 9.6e-100 333.6 0.0 1.2e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RhoGAP PF00620.22 KEZ39716.1 - 5.1e-16 58.6 0.3 1.6e-15 57.0 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KEZ39716.1 - 2.1e-14 53.4 0.0 1.5e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KEZ39716.1 - 3.1e-12 46.0 0.0 6.8e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MRC1 PF09444.5 KEZ39716.1 - 0.12 12.6 1.9 0.33 11.2 1.3 1.8 1 0 0 1 1 1 0 MRC1-like domain Adaptin_N PF01602.15 KEZ39717.1 - 3e-84 283.2 0.0 4.9e-84 282.5 0.0 1.3 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KEZ39717.1 - 0.00013 22.2 2.5 0.22 11.8 0.0 4.3 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 KEZ39717.1 - 0.0023 17.8 0.1 5.1 7.4 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat BLVR PF06375.6 KEZ39717.1 - 0.027 14.2 1.5 0.43 10.3 0.0 2.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Cnd1 PF12717.2 KEZ39717.1 - 0.084 12.7 0.6 19 5.0 0.0 2.5 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_14 PF13428.1 KEZ39719.1 - 1.8e-07 31.1 1.0 0.059 14.0 0.2 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ39719.1 - 2.8e-07 30.0 4.5 0.00031 20.3 0.2 4.0 3 1 1 5 5 5 2 TPR repeat TPR_19 PF14559.1 KEZ39719.1 - 2.1e-06 27.9 0.8 0.011 16.0 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ39719.1 - 5.3e-06 25.9 1.1 0.0061 16.3 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ39719.1 - 1.3e-05 24.6 0.6 0.096 12.5 0.2 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ39719.1 - 7.7e-05 23.2 6.0 0.00026 21.5 0.1 3.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ39719.1 - 0.00037 20.4 0.2 0.076 13.2 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ39719.1 - 0.00091 19.1 4.3 0.88 9.5 0.5 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ39719.1 - 0.0012 19.1 4.1 7.9 7.1 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ39719.1 - 0.022 14.3 0.1 0.4 10.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ39719.1 - 0.072 13.2 2.5 0.15 12.2 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 KEZ39719.1 - 0.1 11.3 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR_3 PF13812.1 KEZ39719.1 - 0.12 12.6 0.0 0.63 10.4 0.0 2.2 2 0 0 2 2 1 0 Pentatricopeptide repeat domain TPR_7 PF13176.1 KEZ39719.1 - 0.14 12.0 2.2 4.7 7.2 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RuvB_C PF05491.8 KEZ39721.1 - 0.16 11.5 0.6 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB C-terminus Methyltransf_12 PF08242.7 KEZ39722.1 - 7.5e-15 55.2 0.2 2.2e-14 53.7 0.0 1.9 2 1 1 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ39722.1 - 5.8e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39722.1 - 3.2e-12 46.7 0.0 7.3e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ39722.1 - 1.3e-11 44.7 0.0 2.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39722.1 - 5.9e-11 42.9 0.0 1.4e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39722.1 - 1.2e-09 37.8 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ39722.1 - 1.6e-06 28.0 0.0 3.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ39722.1 - 3.5e-06 26.2 0.0 5.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ39722.1 - 0.00016 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.3 KEZ39722.1 - 0.0023 16.7 0.0 0.0039 15.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) NNMT_PNMT_TEMT PF01234.12 KEZ39722.1 - 0.0027 16.7 0.0 0.13 11.1 0.0 2.4 1 1 2 3 3 3 1 NNMT/PNMT/TEMT family Methyltransf_16 PF10294.4 KEZ39722.1 - 0.004 16.6 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 KEZ39722.1 - 0.026 15.3 0.0 0.058 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KEZ39722.1 - 0.031 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 KEZ39722.1 - 0.078 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Y_phosphatase3 PF13350.1 KEZ39723.1 - 2.3e-27 96.2 0.6 2e-26 93.1 0.4 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KEZ39723.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KEZ39723.1 - 0.00066 19.0 0.1 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEZ39723.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3812 PF12757.2 KEZ39724.1 - 6.9e-27 93.9 6.2 6.9e-27 93.9 4.3 3.6 2 2 1 3 3 3 1 Protein of unknown function (DUF3812) Frag1 PF10277.4 KEZ39725.1 - 4.1e-45 153.8 10.9 4.8e-45 153.6 7.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF687 PF05095.7 KEZ39725.1 - 0.0022 16.4 1.2 0.0029 16.0 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF687) 7TM_GPCR_Srh PF10318.4 KEZ39725.1 - 0.047 12.4 4.5 0.079 11.7 3.1 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF3995 PF13160.1 KEZ39725.1 - 0.059 13.4 3.3 1.5 8.9 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) Cation_efflux PF01545.16 KEZ39725.1 - 0.083 11.9 7.3 0.16 11.0 5.1 1.4 1 0 0 1 1 1 0 Cation efflux family DUF3413 PF11893.3 KEZ39725.1 - 0.11 11.4 9.9 0.37 9.6 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) DUF2955 PF11168.3 KEZ39725.1 - 0.78 9.4 9.5 0.093 12.4 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2955) NfeD PF01957.13 KEZ39725.1 - 0.9 9.6 4.8 1.1 9.4 0.1 2.6 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Mid1 PF12929.2 KEZ39726.1 - 1.6e-119 399.4 1.4 2e-119 399.1 1.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KEZ39726.1 - 0.14 12.4 7.3 0.98 9.7 1.6 2.6 2 1 0 2 2 2 0 Fz domain TB2_DP1_HVA22 PF03134.14 KEZ39727.1 - 1.9e-31 107.6 6.4 2.6e-31 107.2 4.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 KEZ39727.1 - 0.03 13.2 1.0 2.5 6.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RFX_DNA_binding PF02257.10 KEZ39728.1 - 1.4e-29 102.0 0.1 6.2e-29 99.9 0.1 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain AA_kinase PF00696.23 KEZ39729.1 - 7.4e-36 123.9 0.0 2.6e-35 122.1 0.0 1.9 2 1 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 KEZ39729.1 - 1.9e-13 49.6 4.1 1.6e-10 40.3 0.2 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 KEZ39729.1 - 3.9e-12 45.3 0.6 8.3e-10 37.9 0.0 2.6 2 0 0 2 2 2 2 ACT domain Sec10 PF07393.6 KEZ39730.1 - 2.6e-166 554.8 0.0 3e-166 554.6 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KEZ39730.1 - 8.3e-09 35.0 1.0 2.3e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEZ39730.1 - 5.3e-06 25.9 0.1 1.3e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain CLPTM1 PF05602.7 KEZ39731.1 - 1.5e-144 482.0 0.0 2e-144 481.6 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1453 PF07301.6 KEZ39731.1 - 0.97 9.2 7.0 0.081 12.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) Sec16_C PF12931.2 KEZ39732.1 - 1e-90 304.3 0.0 1.4e-90 303.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KEZ39732.1 - 5.9e-29 100.4 0.0 1.1e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Aurora-A_bind PF09041.5 KEZ39732.1 - 0.043 13.5 0.5 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 Aurora-A binding ChAPs PF09295.5 KEZ39732.1 - 1.8 7.2 0.0 2.7 6.6 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TRAP_alpha PF03896.11 KEZ39733.1 - 1.7e-10 40.3 0.0 2.6e-10 39.7 0.0 1.3 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit IGPD PF00475.13 KEZ39734.1 - 3.1e-61 205.4 0.4 4.2e-61 205.0 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF372 PF04036.7 KEZ39734.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF372) ArgJ PF01960.13 KEZ39735.1 - 1e-143 478.4 0.0 1.2e-143 478.2 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Elong_Iki1 PF10483.4 KEZ39736.1 - 2.5e-78 263.2 0.0 3e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 ASXH PF13919.1 KEZ39737.1 - 6.9e-26 90.6 0.2 9.9e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Asx homology domain PSCyt2 PF07583.6 KEZ39737.1 - 0.051 13.0 0.5 0.073 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) APH PF01636.18 KEZ39738.1 - 1.6e-17 64.0 0.0 3.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEZ39738.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 KEZ39738.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Longin PF13774.1 KEZ39739.1 - 8.1e-28 95.8 0.1 1.4e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KEZ39739.1 - 1.3e-15 56.7 0.1 9.1e-15 54.0 0.0 2.0 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 KEZ39739.1 - 0.05 13.4 0.4 0.05 13.4 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4404 PF14357.1 KEZ39739.1 - 0.57 10.6 2.4 35 4.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Hus1 PF04005.7 KEZ39741.1 - 4.8e-80 268.6 0.0 5.4e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Med5 PF08689.5 KEZ39742.1 - 3e-249 829.6 0.0 4e-249 829.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF2593 PF10767.4 KEZ39742.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) TetR_C PF02909.12 KEZ39742.1 - 0.06 12.9 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain SNF2_N PF00176.18 KEZ39743.1 - 1.6e-55 188.0 1.7 2.6e-55 187.3 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KEZ39743.1 - 1.9e-08 34.0 10.5 4.7e-08 32.7 7.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEZ39743.1 - 3.8e-07 30.0 10.5 8.5e-07 28.9 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ39743.1 - 3.8e-07 29.6 9.1 8.8e-07 28.5 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ39743.1 - 1.7e-06 27.5 8.8 3.5e-06 26.5 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ39743.1 - 1.5e-05 24.6 9.4 2.6e-05 23.8 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KEZ39743.1 - 9.7e-05 22.4 4.6 0.00028 20.9 3.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KEZ39743.1 - 0.14 11.9 5.7 0.16 11.7 1.9 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEZ39743.1 - 0.19 11.6 6.0 0.61 9.9 4.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KEZ39743.1 - 0.38 10.3 6.3 0.84 9.2 4.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KEZ39743.1 - 0.43 10.1 7.6 0.54 9.8 4.0 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KEZ39743.1 - 1.1 9.0 8.0 0.97 9.3 3.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad4 PF03835.10 KEZ39744.1 - 0.0058 16.0 6.1 0.0093 15.3 4.2 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain CDC45 PF02724.9 KEZ39744.1 - 0.13 10.3 13.6 0.17 9.9 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KEZ39744.1 - 6.1 4.3 9.3 7.4 4.1 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SMAP PF15477.1 KEZ39745.1 - 1.2e-17 63.9 3.6 1.2e-17 63.9 2.5 5.2 4 2 0 4 4 4 1 Small acidic protein family DUF3138 PF11336.3 KEZ39745.1 - 1.4 6.9 6.1 2.2 6.3 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RAMP4 PF06624.7 KEZ39746.1 - 8.7e-05 21.9 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.6 KEZ39746.1 - 0.068 12.9 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) Rox3 PF08633.5 KEZ39747.1 - 3.1e-38 132.0 1.5 3.1e-38 132.0 1.1 1.6 2 0 0 2 2 2 1 Rox3 mediator complex subunit DUF3275 PF11679.3 KEZ39747.1 - 0.54 9.8 5.4 3.3 7.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) PGAP1 PF07819.8 KEZ39748.1 - 5.5e-07 29.4 0.0 1.8e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEZ39748.1 - 2.9e-06 27.1 0.0 8.2e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEZ39748.1 - 1.2e-05 24.7 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEZ39748.1 - 2e-05 24.5 1.4 3.6e-05 23.7 0.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ39748.1 - 0.0044 16.6 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KEZ39748.1 - 0.02 15.1 1.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 KEZ39748.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.7 KEZ39748.1 - 0.079 12.6 0.2 0.079 12.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF3449 PF11931.3 KEZ39748.1 - 0.13 11.7 2.3 0.28 10.6 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) She9_MDM33 PF05546.6 KEZ39748.1 - 0.15 11.6 2.5 0.31 10.5 1.7 1.5 1 0 0 1 1 1 0 She9 / Mdm33 family DUF4463 PF14703.1 KEZ39748.1 - 0.23 11.9 4.6 0.77 10.3 3.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) HAUS-augmin3 PF14932.1 KEZ39748.1 - 0.27 10.4 5.1 0.21 10.7 2.3 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Totivirus_coat PF05518.6 KEZ39748.1 - 2 6.1 5.6 3.6 5.2 3.9 1.3 1 0 0 1 1 1 0 Totivirus coat protein TIMELESS PF04821.9 KEZ39749.1 - 1.8e-85 286.4 0.0 1.8e-85 286.4 0.0 2.8 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.8 KEZ39749.1 - 7.6e-19 68.0 37.4 7.6e-19 68.0 25.9 3.8 3 1 0 3 3 3 1 Timeless protein C terminal region 3HCDH_N PF02737.13 KEZ39750.1 - 4.9e-52 176.1 1.6 6.5e-52 175.7 1.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEZ39750.1 - 3.3e-34 117.1 0.0 7.1e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KEZ39750.1 - 0.00016 21.5 0.2 0.00035 20.4 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEZ39750.1 - 0.047 13.4 2.4 0.11 12.2 1.7 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KEZ39750.1 - 0.067 12.3 0.3 0.26 10.3 0.1 1.9 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PHBC_N PF12551.3 KEZ39750.1 - 0.21 11.1 0.7 0.57 9.7 0.5 1.7 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal F420_oxidored PF03807.12 KEZ39750.1 - 0.22 11.9 2.2 1.5 9.3 1.6 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Homeobox PF00046.24 KEZ39751.1 - 1.1e-17 63.3 2.8 2.1e-17 62.4 2.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KEZ39751.1 - 0.0035 17.0 0.1 0.0081 15.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Ribosomal_60s PF00428.14 KEZ39751.1 - 0.4 11.1 3.5 0.92 9.9 2.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein HCO3_cotransp PF00955.16 KEZ39752.1 - 8.4e-69 232.5 9.7 7.8e-42 143.5 2.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family Peptidase_M41 PF01434.13 KEZ39753.1 - 3.3e-73 245.6 0.1 5.5e-73 244.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEZ39753.1 - 3.9e-42 143.5 0.0 7.8e-42 142.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KEZ39753.1 - 1.4e-08 34.8 0.1 4.9e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KEZ39753.1 - 0.00019 21.2 0.0 0.00059 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEZ39753.1 - 0.00079 19.5 0.0 0.53 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEZ39753.1 - 0.0022 17.4 0.9 0.013 14.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 KEZ39753.1 - 0.0042 15.8 0.0 0.0083 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KEZ39753.1 - 0.0097 16.7 0.0 0.035 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ39753.1 - 0.012 15.3 0.1 0.012 15.3 0.1 2.5 3 0 0 3 3 3 0 Part of AAA domain RuvB_N PF05496.7 KEZ39753.1 - 0.013 14.5 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEZ39753.1 - 0.014 15.4 0.2 0.33 10.9 0.1 2.5 1 1 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 KEZ39753.1 - 0.024 14.5 0.0 0.082 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 KEZ39753.1 - 0.027 13.5 0.2 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 KEZ39753.1 - 0.028 13.8 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KEZ39753.1 - 0.065 13.5 0.0 0.21 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEZ39753.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KEZ39754.1 - 6.1e-30 103.9 0.1 1.3e-29 102.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ39754.1 - 1.7e-10 40.6 11.0 3e-10 39.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.3 KEZ39754.1 - 0.18 10.2 0.0 0.39 9.1 0.0 1.5 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor MSA-2c PF12238.3 KEZ39754.1 - 8.9 5.9 12.0 3.5 7.2 0.4 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Adeno_E3_CR2 PF02439.10 KEZ39755.1 - 0.035 13.6 0.2 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 tRNA-synt_1e PF01406.14 KEZ39756.1 - 1.4e-110 369.1 0.0 1.9e-110 368.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KEZ39756.1 - 5.6e-05 21.9 0.2 0.36 9.4 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KEZ39756.1 - 0.00045 20.3 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 DALR domain LSM PF01423.17 KEZ39758.1 - 4.3e-15 54.9 0.3 6.1e-15 54.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain UQ_con PF00179.21 KEZ39759.1 - 1.7e-51 173.3 0.0 1.9e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ39759.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B TPR_11 PF13414.1 KEZ39760.1 - 2.1e-09 36.8 0.1 1.2e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEZ39760.1 - 2.3e-05 23.9 0.7 2.1 8.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.26 KEZ39760.1 - 4.8e-05 23.0 0.0 0.00029 20.5 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.1 KEZ39760.1 - 0.0002 21.2 0.4 0.0055 16.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ39760.1 - 0.00055 19.4 0.5 1.2 8.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DnaJ PF00226.26 KEZ39760.1 - 0.061 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain DUF1996 PF09362.5 KEZ39761.1 - 1.7e-71 240.5 0.0 2.3e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Trypan_PARP PF05887.6 KEZ39761.1 - 3.9e-09 36.4 36.9 7e-09 35.6 25.6 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF2360 PF10152.4 KEZ39761.1 - 1.6 9.0 7.0 2.6 8.2 4.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Neisseria_TspB PF05616.8 KEZ39761.1 - 4.1 5.6 22.6 5.9 5.1 15.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Voldacs PF03517.8 KEZ39762.1 - 3.7e-21 75.3 0.0 7.1e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Opi1 PF08618.5 KEZ39764.1 - 1.2e-84 284.7 3.3 6.2e-60 203.3 7.5 3.1 1 1 1 2 2 2 2 Transcription factor Opi1 Muted PF14942.1 KEZ39764.1 - 2.7 7.8 7.7 1.6 8.5 0.9 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Rubis-subs-bind PF09273.6 KEZ39765.1 - 2.7e-08 33.7 0.2 7e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KEZ39765.1 - 1.2e-06 28.9 0.0 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Adap_comp_sub PF00928.16 KEZ39767.1 - 4.6e-91 304.5 0.0 6.1e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEZ39767.1 - 1.4e-08 34.5 0.3 2.3e-08 33.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RecU PF03838.9 KEZ39767.1 - 0.054 13.0 0.5 2.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Recombination protein U muHD PF10291.4 KEZ39767.1 - 0.089 11.9 0.0 0.44 9.6 0.0 1.9 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain WSC PF01822.14 KEZ39768.1 - 4.2e-14 52.2 5.8 9.7e-14 51.0 4.0 1.7 1 0 0 1 1 1 1 WSC domain Spore_YtfJ PF09579.5 KEZ39768.1 - 3.4 7.6 8.2 9 6.2 5.7 1.8 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Mito_carr PF00153.22 KEZ39769.1 - 1.3e-15 56.8 0.1 0.008 15.8 0.0 5.3 4 1 0 4 4 4 4 Mitochondrial carrier protein DUF883 PF05957.8 KEZ39769.1 - 0.0047 17.2 0.6 0.01 16.2 0.4 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Mito_fiss_reg PF05308.6 KEZ39769.1 - 0.64 9.3 3.8 1.1 8.5 2.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Fer2 PF00111.22 KEZ39770.1 - 2.2e-13 49.7 2.0 2.9e-13 49.3 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_45 PF02015.11 KEZ39771.1 - 1.4e-47 162.3 12.8 1.6e-47 162.1 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 tRNA-synt_1c PF00749.16 KEZ39772.1 - 4e-98 327.9 0.0 5.4e-98 327.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEZ39772.1 - 1.6e-40 138.6 0.0 3.2e-40 137.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KEZ39772.1 - 0.0066 15.5 0.3 0.02 14.0 0.2 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.16 KEZ39773.1 - 1.8e-22 79.7 0.0 2.5e-22 79.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF1399 PF07173.7 KEZ39775.1 - 5e-20 72.1 3.1 7.6e-15 55.4 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) F-box PF00646.28 KEZ39775.1 - 0.072 12.7 0.3 0.23 11.1 0.2 1.9 1 0 0 1 1 1 0 F-box domain Nop14 PF04147.7 KEZ39775.1 - 0.29 9.0 8.6 0.37 8.6 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family GMC_oxred_N PF00732.14 KEZ39776.1 - 9.6e-51 172.6 0.0 1.4e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39776.1 - 9.5e-28 97.3 0.0 1.6e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ39776.1 - 0.00016 20.7 0.1 0.006 15.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ39776.1 - 0.0007 18.5 0.1 0.027 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ39776.1 - 0.001 19.0 0.1 0.0028 17.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ39776.1 - 0.0093 16.0 0.0 0.19 11.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ39776.1 - 0.0093 15.0 0.1 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ39776.1 - 0.016 15.1 0.0 1 9.2 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acyltransferase PF01553.16 KEZ39778.1 - 1.1e-17 63.6 0.0 2.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase F-box-like PF12937.2 KEZ39779.1 - 2.3e-07 30.4 0.3 5.8e-07 29.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ39779.1 - 2.9e-05 23.5 0.0 6.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 KEZ39780.1 - 3e-21 75.7 0.0 5.7e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39780.1 - 1.4e-05 24.3 0.3 0.00017 20.7 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HeLo PF14479.1 KEZ39781.1 - 3e-35 121.9 0.5 5.2e-35 121.1 0.4 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation NACHT PF05729.7 KEZ39781.1 - 2.2e-11 43.7 0.0 1e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ39781.1 - 0.0018 18.4 0.0 0.008 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ39781.1 - 0.022 14.7 0.2 0.11 12.4 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KEZ39781.1 - 0.092 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KEZ39781.1 - 0.093 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEZ39781.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ39781.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEZ39781.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 KEZ39781.1 - 0.16 10.8 0.0 0.6 8.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Alpha_GJ PF03229.8 KEZ39782.1 - 0.0026 18.0 0.1 0.0064 16.8 0.1 1.6 1 0 0 1 1 1 1 Alphavirus glycoprotein J Herpes_gE PF02480.11 KEZ39782.1 - 0.0027 16.0 0.0 0.0034 15.7 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E FixQ PF05545.6 KEZ39782.1 - 0.0089 15.6 0.2 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ DUF1049 PF06305.6 KEZ39782.1 - 0.019 14.3 0.3 0.036 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SKG6 PF08693.5 KEZ39782.1 - 0.022 14.0 0.5 0.043 13.1 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box PF00646.28 KEZ39784.1 - 0.0064 16.1 0.2 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.17 KEZ39785.1 - 1.2e-135 452.4 0.0 1.4e-135 452.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ39785.1 - 1.5e-05 23.9 0.0 5.3e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) NMD3 PF04981.8 KEZ39786.1 - 4.6e-70 235.3 0.8 6.7e-70 234.8 0.6 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 KEZ39786.1 - 0.16 11.8 3.5 2.3 8.1 1.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.3 KEZ39786.1 - 0.16 11.9 4.4 0.6 10.0 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) FYVE PF01363.16 KEZ39786.1 - 0.47 10.3 2.6 2.7 7.9 0.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF3662 PF12401.3 KEZ39787.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) DUF3112 PF11309.3 KEZ39788.1 - 2.7e-48 163.7 15.3 4e-44 150.2 2.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) BatA PF07584.6 KEZ39788.1 - 0.089 12.9 0.4 0.089 12.9 0.3 3.5 2 2 1 3 3 3 0 Aerotolerance regulator N-terminal Aminotran_1_2 PF00155.16 KEZ39789.1 - 1.1e-81 274.5 0.0 1.3e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Adaptin_N PF01602.15 KEZ39790.1 - 6.2e-133 443.8 11.6 7.7e-133 443.5 8.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KEZ39790.1 - 4e-19 69.1 0.5 4e-19 69.1 0.3 2.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEZ39790.1 - 5.6e-17 61.7 4.1 2.6e-10 40.4 0.1 4.7 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.17 KEZ39790.1 - 1.1e-11 43.7 3.6 0.00061 19.6 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KEZ39790.1 - 8.7e-07 29.2 6.6 0.031 14.7 0.0 6.2 5 1 1 6 6 6 2 HEAT-like repeat Atx10homo_assoc PF09759.4 KEZ39790.1 - 6.3e-05 22.6 0.3 0.07 12.8 0.0 3.8 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 KEZ39790.1 - 0.001 18.8 3.5 3.9 7.4 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KEZ39790.1 - 0.004 16.5 1.4 3 7.1 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal RIX1 PF08167.7 KEZ39790.1 - 0.0088 15.7 0.4 0.16 11.6 0.0 2.8 2 2 1 3 3 3 1 rRNA processing/ribosome biogenesis DUF2435 PF10363.4 KEZ39790.1 - 0.048 13.5 2.2 1.5 8.7 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) DUF1077 PF06417.7 KEZ39791.1 - 3e-32 110.6 4.3 5.5e-32 109.7 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Syntaxin-18_N PF10496.4 KEZ39791.1 - 2.5e-14 52.8 0.7 9e-14 51.0 0.1 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KEZ39791.1 - 0.023 14.3 2.1 0.08 12.6 0.5 2.6 2 0 0 2 2 2 0 SNARE domain Fib_alpha PF08702.5 KEZ39791.1 - 1.6 8.8 6.7 9.6 6.3 0.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rad60-SLD_2 PF13881.1 KEZ39792.1 - 1.5e-11 44.1 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEZ39792.1 - 0.00034 19.9 0.0 0.00065 19.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KEZ39792.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 KEZ39793.1 - 2.4e-23 82.5 0.0 2.8e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Mucin PF01456.12 KEZ39793.1 - 1.1 8.9 7.3 1.8 8.3 5.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein APH PF01636.18 KEZ39794.1 - 3.8e-10 39.9 0.0 4.8e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ39794.1 - 1.2e-08 34.8 0.0 4.8e-08 32.8 0.0 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KEZ39794.1 - 0.0063 15.1 0.1 0.025 13.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Chitin_synth_1 PF01644.12 KEZ39795.1 - 6.6e-85 282.8 0.2 1e-84 282.2 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KEZ39795.1 - 2.9e-33 113.3 0.1 6.4e-33 112.2 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KEZ39795.1 - 1.2e-23 83.3 1.1 1.3e-20 73.2 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KEZ39795.1 - 1.6e-09 37.7 7.0 1.6e-09 37.7 4.8 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ39795.1 - 6.6e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NIR_SIR PF01077.17 KEZ39796.1 - 2.8e-54 182.7 0.1 1.1e-46 158.0 0.1 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KEZ39796.1 - 5.3e-31 106.0 0.0 4.6e-15 54.9 0.0 2.9 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KEZ39796.1 - 5.4e-31 107.5 0.0 1.3e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KEZ39796.1 - 3e-06 26.9 0.1 7.7e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 KEZ39797.1 - 1.1e-44 152.4 6.7 1.5e-44 151.8 4.6 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2975 PF11188.3 KEZ39797.1 - 0.16 11.6 6.8 0.035 13.8 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Rib_5-P_isom_A PF06026.9 KEZ39798.1 - 5e-39 133.3 0.0 8e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KEZ39798.1 - 0.1 12.2 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Ras PF00071.17 KEZ39799.1 - 3.5e-22 78.5 0.1 5.1e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KEZ39799.1 - 0.00019 20.7 0.1 0.00025 20.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEZ39799.1 - 0.019 14.4 0.1 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Nop53 PF07767.6 KEZ39800.1 - 8.2e-100 334.4 29.3 1e-99 334.1 20.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PRK PF00485.13 KEZ39800.1 - 6.5e-56 188.9 0.7 9.1e-56 188.4 0.0 1.6 2 0 0 2 2 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KEZ39800.1 - 1.5e-40 138.6 0.0 2.6e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 KEZ39800.1 - 1e-08 36.0 0.0 1e-08 36.0 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KEZ39800.1 - 1.8e-06 28.2 0.0 1.8e-06 28.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain CPT PF07931.7 KEZ39800.1 - 6.8e-06 25.8 0.0 2.7e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 KEZ39800.1 - 0.00027 20.8 0.0 0.00027 20.8 0.0 3.4 3 1 0 3 3 2 1 AAA domain ABC_tran PF00005.22 KEZ39800.1 - 0.011 16.0 2.4 0.016 15.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 KEZ39800.1 - 0.017 14.6 0.8 0.042 13.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KEZ39800.1 - 0.031 13.1 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KEZ39800.1 - 0.05 13.3 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KEZ39800.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.1 3 1 0 3 3 2 0 AAA ATPase domain DUF87 PF01935.12 KEZ39800.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF4407 PF14362.1 KEZ39800.1 - 6.9 5.5 25.7 11 4.8 17.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.6 KEZ39800.1 - 8.5 4.5 20.8 16 3.6 14.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Pyr_redox_2 PF07992.9 KEZ39801.1 - 5.5e-21 75.3 0.0 1e-20 74.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ39801.1 - 3.7e-14 52.8 2.1 5.2e-11 42.7 0.0 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 KEZ39801.1 - 3.8e-07 28.9 0.4 9.1e-07 27.7 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KEZ39801.1 - 5.2e-06 25.9 0.6 2e-05 24.0 0.4 2.0 1 0 0 1 1 1 1 EF-hand domain Pyr_redox_3 PF13738.1 KEZ39801.1 - 2.1e-05 24.6 0.0 0.77 9.7 0.0 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 KEZ39801.1 - 2.9e-05 24.1 0.2 7.7e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KEZ39801.1 - 6e-05 22.2 2.0 0.00013 21.0 1.4 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KEZ39801.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Tudor-knot PF11717.3 KEZ39802.1 - 8e-19 67.1 0.0 2.1e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MOZ_SAS PF01853.13 KEZ39802.1 - 1.2e-08 34.4 0.1 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family ESX-1_EspG PF14011.1 KEZ39802.1 - 0.08 12.1 0.4 0.57 9.3 0.0 2.0 2 0 0 2 2 2 0 EspG family CLTH PF10607.4 KEZ39803.1 - 6.3e-31 107.0 0.0 2e-30 105.4 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KEZ39803.1 - 5.1e-07 29.2 0.2 9.2e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 LisH ETC_C1_NDUFA4 PF04800.7 KEZ39804.1 - 3.8e-35 119.7 1.6 6.3e-35 119.0 1.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 KEZ39805.1 - 6e-39 132.1 1.1 6.7e-39 132.0 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KEZ39805.1 - 0.023 14.7 0.2 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f MCM PF00493.18 KEZ39807.1 - 3.9e-136 453.1 3.0 7.5e-136 452.2 2.1 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEZ39807.1 - 1.3e-20 74.0 1.3 3.6e-20 72.6 0.0 2.3 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEZ39807.1 - 2.7e-07 29.9 0.2 1e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEZ39807.1 - 0.0013 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KEZ39807.1 - 0.0015 18.1 0.1 0.0042 16.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ39807.1 - 0.038 13.7 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CMAS PF02353.15 KEZ39808.1 - 6.4e-72 241.9 0.0 1.8e-71 240.3 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KEZ39808.1 - 5.2e-12 45.7 0.0 9.3e-12 44.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39808.1 - 7.8e-09 36.1 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39808.1 - 6.2e-08 33.0 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39808.1 - 1.7e-06 27.6 0.0 2.6e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39808.1 - 1.6e-05 25.2 0.0 3.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEZ39808.1 - 8.4e-05 22.1 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KEZ39808.1 - 0.00033 20.6 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEZ39808.1 - 0.0035 16.4 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.4 KEZ39808.1 - 0.055 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KEZ39808.1 - 0.085 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KEZ39808.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Snf7 PF03357.16 KEZ39809.1 - 1.6e-20 73.1 14.6 2.3e-20 72.6 10.1 1.2 1 0 0 1 1 1 1 Snf7 BLOC1_2 PF10046.4 KEZ39809.1 - 0.12 12.5 6.7 0.39 10.8 1.0 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 KEZ39809.1 - 0.13 12.1 8.0 1.7 8.5 0.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 KEZ39809.1 - 0.17 11.6 10.1 1.5 8.5 2.1 2.6 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 KEZ39809.1 - 0.18 12.0 11.6 4.5 7.5 0.2 4.1 1 1 4 5 5 5 0 Nucleopolyhedrovirus P10 protein UPF0184 PF03670.8 KEZ39809.1 - 0.28 11.3 5.1 1.5 9.0 0.4 2.9 2 1 0 3 3 2 0 Uncharacterised protein family (UPF0184) AAA_13 PF13166.1 KEZ39809.1 - 0.56 8.5 7.8 0.79 8.1 5.4 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KEZ39809.1 - 0.93 9.3 7.9 12 5.7 3.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.6 KEZ39809.1 - 1.3 8.4 12.8 2.9 7.2 3.7 2.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 KEZ39809.1 - 1.8 7.6 9.3 1.4 8.0 4.9 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Matrilin_ccoil PF10393.4 KEZ39809.1 - 1.9 7.9 4.7 21 4.5 0.1 3.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Allexi_40kDa PF05549.6 KEZ39809.1 - 4.1 6.6 6.9 5.6 6.1 3.5 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein Mnd1 PF03962.10 KEZ39809.1 - 4.9 6.7 12.3 1.4 8.5 5.2 2.1 1 1 2 3 3 3 0 Mnd1 family Hpt PF01627.18 KEZ39809.1 - 7.5 6.6 13.0 0.33 10.9 3.9 2.7 3 1 0 3 3 3 0 Hpt domain SAP PF02037.22 KEZ39810.1 - 2.5e-05 23.6 0.1 4.1e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 SAP domain Sgf11 PF08209.6 KEZ39810.1 - 0.0023 17.2 0.1 0.0045 16.2 0.0 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 KEZ39810.1 - 0.018 14.6 0.2 0.032 13.9 0.2 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Kri1 PF05178.7 KEZ39810.1 - 0.19 12.0 2.1 0.33 11.2 1.4 1.6 1 1 0 1 1 1 0 KRI1-like family CDC27 PF09507.5 KEZ39811.1 - 6.5e-61 206.8 17.8 7.7e-61 206.6 12.3 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Aminotran_1_2 PF00155.16 KEZ39811.1 - 9e-15 54.4 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Porin_O_P PF07396.6 KEZ39811.1 - 0.07 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphate-selective porin O and P RNase_Zc3h12a PF11977.3 KEZ39811.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain DUF1237 PF06824.6 KEZ39812.1 - 2.1e-162 540.5 0.0 2.5e-159 530.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1237) NTP_transf_2 PF01909.18 KEZ39814.1 - 0.0028 17.9 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pribosyltran_N PF13793.1 KEZ39815.1 - 4.4e-41 139.2 0.0 6.3e-40 135.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEZ39815.1 - 2.2e-34 118.8 0.0 9.8e-30 103.6 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEZ39815.1 - 5.4e-05 22.9 0.0 0.0071 16.0 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Polysacc_deac_1 PF01522.16 KEZ39816.1 - 2.4e-26 91.7 0.0 5.1e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Na_H_Exchanger PF00999.16 KEZ39817.1 - 1.3e-36 126.0 31.1 1.6e-36 125.7 21.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GMC_oxred_N PF00732.14 KEZ39818.1 - 1.2e-56 192.0 0.0 1.5e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39818.1 - 6.4e-25 88.1 0.0 1.3e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ39818.1 - 2.6e-08 33.1 0.4 1.2e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ39818.1 - 1.7e-06 27.2 0.3 2.5e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ39818.1 - 6.5e-06 26.1 0.0 0.00033 20.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ39818.1 - 6.7e-05 22.8 0.6 0.00018 21.4 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ39818.1 - 9.4e-05 21.4 4.7 0.0011 17.8 1.4 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KEZ39818.1 - 0.00055 19.1 0.1 0.001 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ39818.1 - 0.0024 16.4 0.6 0.0053 15.2 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KEZ39818.1 - 0.019 15.3 0.4 0.2 12.0 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ39818.1 - 0.024 13.7 1.5 0.033 13.2 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 KEZ39818.1 - 0.038 12.6 0.1 0.056 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GDI PF00996.13 KEZ39818.1 - 0.088 11.1 0.1 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.13 KEZ39818.1 - 0.14 12.1 0.2 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 KEZ39818.1 - 0.31 9.8 1.6 0.26 10.1 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF4064 PF13273.1 KEZ39819.1 - 0.013 15.5 2.4 15 5.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF4084 PF13321.1 KEZ39819.1 - 0.3 10.2 3.2 2.5 7.2 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4084) Sdh_cyt PF01127.17 KEZ39819.1 - 6.8 6.5 14.1 18 5.1 3.3 2.9 1 1 2 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sugar_tr PF00083.19 KEZ39821.1 - 1.3e-19 70.1 22.3 4.6e-09 35.3 6.7 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39821.1 - 1.9e-12 46.6 13.2 2.1e-05 23.4 2.3 3.2 2 1 2 4 4 4 4 Major Facilitator Superfamily ATG22 PF11700.3 KEZ39821.1 - 0.0014 17.2 6.4 0.0014 17.2 4.4 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like PrgI PF12666.2 KEZ39821.1 - 0.59 10.3 5.9 1.9 8.7 0.2 3.4 3 0 0 3 3 3 0 PrgI family protein Pkinase PF00069.20 KEZ39823.1 - 2.1e-24 86.0 0.0 3.4e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 KEZ39823.1 - 3.2e-21 75.9 0.0 6.6e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KEZ39824.1 - 4.1e-17 62.1 0.0 2e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39824.1 - 1.1e-06 27.8 0.0 0.0038 16.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase p450 PF00067.17 KEZ39825.1 - 1.4e-17 63.4 0.0 4.5e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 KEZ39827.1 - 1.3e-76 257.6 35.9 1.4e-39 136.1 8.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ39827.1 - 1.1e-70 236.2 0.0 3.6e-34 118.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ39827.1 - 4.3e-14 52.2 1.7 5.8e-05 22.4 0.0 4.0 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ39827.1 - 1.8e-12 47.8 0.0 0.039 13.9 0.0 4.4 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 KEZ39827.1 - 4.6e-11 41.9 0.3 0.0021 16.7 0.1 3.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KEZ39827.1 - 1e-10 41.9 0.8 5.1e-05 23.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KEZ39827.1 - 1.2e-09 37.5 0.7 8.4e-05 22.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KEZ39827.1 - 5.6e-08 33.0 0.2 0.011 15.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KEZ39827.1 - 1.2e-07 32.5 0.0 0.02 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEZ39827.1 - 1.6e-07 30.6 0.0 0.013 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEZ39827.1 - 3.2e-07 29.9 0.0 0.038 13.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KEZ39827.1 - 1.4e-05 25.5 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEZ39827.1 - 4.9e-05 23.2 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEZ39827.1 - 0.00011 22.4 0.1 0.74 10.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 KEZ39827.1 - 0.00018 21.7 0.1 5.5 7.2 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KEZ39827.1 - 0.00018 21.1 0.1 3.9 6.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.12 KEZ39827.1 - 0.00099 18.9 0.0 0.83 9.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KEZ39827.1 - 0.0013 18.5 0.2 2.7 7.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) MobB PF03205.9 KEZ39827.1 - 0.0013 18.4 0.0 0.99 9.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KEZ39827.1 - 0.0013 18.7 0.0 0.74 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEZ39827.1 - 0.0017 17.5 0.3 2.1 7.4 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_14 PF13173.1 KEZ39827.1 - 0.0028 17.5 0.0 5.1 7.0 0.0 3.6 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.18 KEZ39827.1 - 0.0046 16.8 0.1 4.2 7.3 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRP54 PF00448.17 KEZ39827.1 - 0.0055 16.1 0.0 0.31 10.4 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KEZ39827.1 - 0.0073 16.0 0.1 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 KEZ39827.1 - 0.0087 15.9 5.7 1.8 8.5 0.1 3.9 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KEZ39827.1 - 0.0093 15.0 0.0 2.5 7.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KEZ39827.1 - 0.02 14.3 1.3 1.7 7.9 0.0 3.2 4 0 0 4 4 3 0 AAA-like domain RNA_helicase PF00910.17 KEZ39827.1 - 0.02 15.0 0.1 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 KEZ39827.1 - 0.039 13.6 0.1 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.10 KEZ39827.1 - 0.062 11.9 0.0 4 6.0 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein G-alpha PF00503.15 KEZ39827.1 - 0.087 11.4 0.0 7.9 5.0 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit F1F0-ATPsyn_F PF10791.4 KEZ39827.1 - 0.094 12.9 0.0 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi NB-ARC PF00931.17 KEZ39827.1 - 0.12 11.1 0.1 8.9 5.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Fungal_trans PF04082.13 KEZ39828.1 - 1.3e-15 56.9 0.0 3.9e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KEZ39829.1 - 1.1e-23 83.9 0.1 1.3e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ39829.1 - 1.5e-09 37.7 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ39829.1 - 2.3e-09 37.3 0.0 2.9e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KEZ39829.1 - 0.033 13.0 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KEZ39829.1 - 0.054 13.2 0.2 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 KEZ39830.1 - 4e-06 26.7 0.0 1.1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 ThiF family Nab1 PF04902.7 KEZ39830.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved region in Nab1 Fungal_trans PF04082.13 KEZ39831.1 - 5.1e-27 94.3 0.1 8.8e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BatA PF07584.6 KEZ39831.1 - 0.093 12.9 1.0 26 5.1 0.0 3.4 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Sugar_tr PF00083.19 KEZ39832.1 - 9.8e-107 357.3 18.8 1.4e-106 356.8 13.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39832.1 - 7.3e-21 74.2 29.0 8e-21 74.1 15.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 KEZ39832.1 - 0.3 9.1 10.2 0.018 13.2 3.4 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector DUF4131 PF13567.1 KEZ39832.1 - 3.4 7.0 12.8 0.2 11.0 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.19 KEZ39833.1 - 1.9e-83 280.5 14.6 2.2e-83 280.3 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39833.1 - 3.2e-28 98.4 12.5 5e-28 97.8 8.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ39833.1 - 1.6e-05 23.2 0.7 1.6e-05 23.2 0.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KEZ39833.1 - 5.3e-05 21.7 3.4 5.3e-05 21.7 2.3 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein Tmemb_170 PF10190.4 KEZ39833.1 - 0.054 13.5 1.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Putative transmembrane protein 170 PalH PF08733.5 KEZ39833.1 - 0.43 9.3 6.8 0.82 8.4 4.7 1.4 1 0 0 1 1 1 0 PalH/RIM21 C2 PF00168.25 KEZ39834.1 - 1.1e-15 57.2 0.1 2.9e-11 43.0 0.3 2.5 2 0 0 2 2 2 2 C2 domain F-box-like PF12937.2 KEZ39835.1 - 0.00042 19.9 0.2 0.0015 18.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KEZ39835.1 - 0.038 13.6 0.2 22 4.8 0.1 3.4 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) FAD_binding_4 PF01565.18 KEZ39836.1 - 1.7e-25 89.1 0.9 2.9e-25 88.3 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_11 PF00457.12 KEZ39836.1 - 0.033 13.5 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 NmrA PF05368.8 KEZ39837.1 - 5.2e-10 38.9 0.0 7.9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family FAD_binding_4 PF01565.18 KEZ39838.1 - 1.7e-18 66.4 1.3 3.4e-18 65.4 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ39838.1 - 1.4e-10 40.9 0.3 1.8e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 KEZ39839.1 - 1.5e-43 148.8 27.5 9.1e-40 136.4 12.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39839.1 - 2.1e-09 36.4 9.8 2.1e-09 36.4 6.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KEZ39839.1 - 0.00024 19.4 4.7 0.00049 18.4 3.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KEZ39839.1 - 0.0019 16.4 3.1 0.0019 16.4 2.2 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.1 KEZ39839.1 - 0.0036 15.7 4.5 0.0036 15.7 3.2 3.1 3 2 0 3 3 3 1 MFS/sugar transport protein DUF3317 PF11779.3 KEZ39839.1 - 6.2 6.3 6.4 3.7 7.0 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) Meth_synt_2 PF01717.13 KEZ39840.1 - 1.3e-22 80.1 0.0 1.6e-16 60.1 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KEZ39840.1 - 1.7e-11 43.9 0.0 7.6e-05 22.1 0.0 3.1 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Archease PF01951.11 KEZ39840.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) adh_short PF00106.20 KEZ39841.1 - 1.5e-05 24.9 0.4 0.00064 19.6 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 KEZ39841.1 - 0.0067 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KEZ39841.1 - 0.098 11.5 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein GMC_oxred_N PF00732.14 KEZ39842.1 - 8.9e-38 130.1 0.0 3e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ39842.1 - 5e-24 85.2 0.0 7.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 KEZ39842.1 - 2.5e-06 27.5 0.0 0.00044 20.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ39842.1 - 0.00019 21.5 0.1 0.61 10.1 0.0 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ39842.1 - 0.0039 16.1 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ39842.1 - 0.005 16.8 0.0 0.005 16.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ39842.1 - 0.0083 15.0 0.1 0.035 12.9 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ39842.1 - 0.023 13.5 0.4 0.044 12.6 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KEZ39842.1 - 0.11 10.9 0.1 0.16 10.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KEZ39842.1 - 0.11 11.4 0.1 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain zf-TRM13_CCCH PF11722.3 KEZ39843.1 - 0.0016 17.7 0.4 0.0016 17.7 0.3 4.9 5 0 0 5 5 5 3 CCCH zinc finger in TRM13 protein Sugar_tr PF00083.19 KEZ39844.1 - 9.5e-58 195.8 14.6 1e-57 195.7 7.5 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter Flavi_NS4A PF01350.12 KEZ39844.1 - 0.49 9.9 5.9 1.1 8.7 4.0 1.7 1 1 0 1 1 1 0 Flavivirus non-structural protein NS4A Glyco_hydro_61 PF03443.9 KEZ39845.1 - 6.5e-35 120.9 0.0 1.3e-34 119.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_S15 PF02129.13 KEZ39846.1 - 2.9e-38 131.8 0.1 4.3e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KEZ39846.1 - 1.4e-20 74.1 0.0 2.2e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.16 KEZ39846.1 - 0.025 13.8 1.4 0.048 12.8 1.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 KEZ39847.1 - 1.4e-23 83.2 0.0 1.6e-11 43.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 KEZ39848.1 - 1e-23 83.3 0.0 1.5e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KEZ39848.1 - 5.6e-12 45.4 0.0 9.4e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.19 KEZ39850.1 - 1.1e-70 238.5 24.3 1.2e-70 238.3 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39850.1 - 3.6e-19 68.6 38.1 3.6e-19 68.6 26.4 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 KEZ39850.1 - 2.6e-06 25.9 1.3 5.1e-06 24.9 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YchF-GTPase_C PF06071.8 KEZ39850.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) DUF3154 PF11351.3 KEZ39850.1 - 0.29 10.9 2.7 0.3 10.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) VirB3 PF05101.8 KEZ39850.1 - 0.59 10.1 3.5 2.9 7.9 2.4 2.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Zn_clus PF00172.13 KEZ39851.1 - 1.2e-10 41.0 7.7 2.7e-10 39.9 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ39851.1 - 1.8e-06 27.0 2.5 2.7e-06 26.4 1.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 KEZ39852.1 - 5.8e-13 49.3 0.1 2.8e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KEZ39852.1 - 0.0085 16.3 0.0 0.026 14.8 0.0 1.8 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase GFO_IDH_MocA PF01408.17 KEZ39853.1 - 5.2e-20 72.1 0.1 1.6e-19 70.5 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 KEZ39853.1 - 0.0084 15.1 0.1 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA_C PF02894.12 KEZ39853.1 - 0.033 13.9 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_2 PF00703.16 KEZ39854.1 - 1.8e-14 54.0 0.4 1.8e-14 54.0 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KEZ39854.1 - 2e-05 24.2 0.2 4.8e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Phosphonate-bd PF12974.2 KEZ39855.1 - 6.9e-06 25.6 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 KEZ39855.1 - 1.5e-05 24.3 0.0 0.00013 21.3 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 KEZ39855.1 - 3.1e-05 23.6 0.0 4.8e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 NMT1/THI5 like DUF3834 PF12916.2 KEZ39855.1 - 0.032 13.2 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) NACHT PF05729.7 KEZ39856.1 - 2.7e-11 43.4 0.0 4.6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ39856.1 - 3.4e-08 33.6 0.0 8.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KEZ39856.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEZ39856.1 - 0.0027 17.8 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KEZ39856.1 - 0.0053 15.7 0.0 0.013 14.4 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 KEZ39856.1 - 0.0086 16.2 0.0 0.047 13.8 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KEZ39856.1 - 0.011 15.1 0.3 0.03 13.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEZ39856.1 - 0.034 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KEZ39856.1 - 0.051 12.2 0.0 0.15 10.6 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 KEZ39856.1 - 0.052 12.3 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 KEZ39856.1 - 0.055 12.4 0.1 0.33 9.8 0.0 2.0 1 1 0 1 1 1 0 KAP family P-loop domain COesterase PF00135.23 KEZ39857.1 - 1.1e-56 192.6 0.0 1.5e-47 162.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ39857.1 - 7.8e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ39857.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KEZ39858.1 - 1.4e-28 99.6 33.1 1.9e-28 99.1 22.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA_12 PF13087.1 KEZ39859.1 - 4.5e-37 127.3 0.0 8e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ39859.1 - 2.2e-20 73.2 0.0 7.7e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain zf-CCCH PF00642.19 KEZ39859.1 - 1.8e-07 30.6 4.4 4.8e-07 29.3 3.0 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_19 PF13245.1 KEZ39859.1 - 5.5e-07 29.2 0.4 2.1e-05 24.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 KEZ39859.1 - 1e-05 24.7 0.1 0.037 13.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KEZ39859.1 - 0.0028 17.6 0.1 0.036 14.0 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.1 KEZ39859.1 - 0.0043 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 KEZ39859.1 - 0.017 14.6 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KEZ39859.1 - 0.15 11.5 0.5 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein zf-C3HC4_3 PF13920.1 KEZ39859.1 - 2.6 7.7 8.7 5.8 6.6 0.0 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_23 PF13489.1 KEZ39862.1 - 5.4e-21 74.9 0.0 8.5e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39862.1 - 1e-10 42.1 0.0 3.3e-09 37.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39862.1 - 1.7e-10 40.6 0.0 4.1e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39862.1 - 3.6e-07 30.5 0.0 6.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39862.1 - 1.6e-06 28.5 0.0 8.9e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ39862.1 - 1.7e-06 28.3 0.0 7.2e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ39862.1 - 9.6e-05 21.8 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KEZ39862.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ39862.1 - 0.00073 19.5 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ39862.1 - 0.00076 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 KEZ39862.1 - 0.0047 16.0 0.0 0.024 13.7 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KEZ39862.1 - 0.0062 15.6 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KEZ39862.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KEZ39862.1 - 0.072 12.6 0.0 1.5 8.2 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FmrO PF07091.6 KEZ39862.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_16 PF10294.4 KEZ39862.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 KEZ39863.1 - 2.5e-16 59.7 0.0 4.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ39863.1 - 1.3e-10 41.6 0.0 2.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ39863.1 - 1.7e-08 34.2 0.0 0.0011 18.5 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ39863.1 - 1.8e-06 28.5 0.0 2e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ39863.1 - 2.2e-06 28.0 0.0 9.7e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ39863.1 - 0.00015 20.9 0.0 0.0026 16.9 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ39863.1 - 0.00035 20.9 0.0 0.0011 19.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ39863.1 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KEZ39863.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEZ39863.1 - 0.025 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KEZ39863.1 - 0.028 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.20 KEZ39864.1 - 5.1e-21 74.9 0.0 8.3e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39864.1 - 1.1e-09 37.8 0.0 6.9e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEZ39864.1 - 0.0098 15.6 0.0 0.25 11.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEZ39864.1 - 0.33 9.6 0.0 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase F-box PF00646.28 KEZ39866.1 - 0.00015 21.2 0.1 0.002 17.7 0.0 2.7 2 0 0 2 2 2 1 F-box domain CorA PF01544.13 KEZ39867.1 - 3.2e-11 42.7 6.9 7.4e-10 38.3 0.0 3.2 3 1 0 3 3 3 2 CorA-like Mg2+ transporter protein DUF717 PF05338.7 KEZ39867.1 - 0.036 14.0 0.1 1.5 8.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF717) GLTSCR1 PF15249.1 KEZ39867.1 - 0.66 10.0 5.2 1.9 8.6 0.0 3.0 2 1 1 3 3 3 0 Glioma tumor suppressor candidate region zf-CCCH PF00642.19 KEZ39868.1 - 8.2e-09 34.9 2.5 1.6e-08 34.0 1.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KEZ39868.1 - 1.4e-08 34.2 4.8 2.2e-08 33.6 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ39868.1 - 5.3e-08 32.7 9.6 9.6e-08 31.9 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ39868.1 - 1.8e-06 27.4 9.1 3.3e-06 26.6 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ39868.1 - 2.8e-06 26.9 7.7 5.1e-06 26.1 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ39868.1 - 4e-06 26.5 6.4 6.6e-06 25.8 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KEZ39868.1 - 0.001 18.7 3.4 0.001 18.7 2.4 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEZ39868.1 - 0.0011 18.8 7.6 0.0026 17.5 5.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Cript PF10235.4 KEZ39868.1 - 0.05 13.9 4.3 0.055 13.8 1.7 2.1 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.2 KEZ39868.1 - 0.052 13.6 1.0 0.13 12.4 0.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 KEZ39868.1 - 0.36 10.3 4.6 0.78 9.3 3.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Beta-lactamase PF00144.19 KEZ39871.1 - 4.5e-32 111.3 0.0 4.1e-31 108.2 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase Zn_clus PF00172.13 KEZ39871.1 - 2.6e-06 27.2 6.2 4.8e-06 26.3 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2985 PF11204.3 KEZ39872.1 - 2.6e-26 91.1 6.1 4.3e-26 90.4 3.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) ABC_tran PF00005.22 KEZ39873.1 - 3.1e-69 231.5 0.0 9.8e-34 116.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ39873.1 - 1.9e-36 125.9 10.5 2.7e-36 125.4 7.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KEZ39873.1 - 3.9e-14 53.2 0.0 0.055 13.4 0.0 4.4 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KEZ39873.1 - 1.5e-13 50.5 1.9 0.00017 20.9 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KEZ39873.1 - 3.6e-10 39.0 1.5 0.00071 18.2 0.1 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KEZ39873.1 - 4.8e-09 35.6 0.6 0.0002 20.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEZ39873.1 - 7.1e-08 31.7 0.0 0.0071 15.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ39873.1 - 1.2e-07 31.8 1.1 0.014 15.4 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KEZ39873.1 - 7.2e-07 30.0 0.1 0.066 14.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KEZ39873.1 - 1.2e-06 28.6 0.3 0.065 13.3 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KEZ39873.1 - 5.7e-06 25.8 0.0 0.077 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KEZ39873.1 - 1.7e-05 24.4 1.9 1.2 8.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KEZ39873.1 - 0.00024 21.5 0.2 0.059 13.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEZ39873.1 - 0.00033 20.5 0.4 0.67 9.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KEZ39873.1 - 0.00063 19.9 0.3 5.9 7.1 0.0 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) F-box-like PF12937.2 KEZ39873.1 - 0.0012 18.4 0.1 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like AAA_18 PF13238.1 KEZ39873.1 - 0.0013 19.0 0.2 1.4 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KEZ39873.1 - 0.0015 18.3 2.5 2.1 8.2 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 KEZ39873.1 - 0.0027 17.4 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KEZ39873.1 - 0.0034 17.0 0.1 4.1 7.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KEZ39873.1 - 0.0048 16.8 1.0 1.1 9.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KEZ39873.1 - 0.0051 16.6 0.1 12 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KEZ39873.1 - 0.0083 16.0 0.2 2.7 7.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KEZ39873.1 - 0.014 14.5 2.2 1.8 7.6 0.0 3.1 4 0 0 4 4 4 0 Zeta toxin DUF87 PF01935.12 KEZ39873.1 - 0.015 15.1 0.3 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KEZ39873.1 - 0.02 14.3 0.7 3.2 7.1 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 KEZ39873.1 - 0.026 14.6 0.1 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.15 KEZ39873.1 - 0.056 12.1 0.0 2.1 6.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit SRP54 PF00448.17 KEZ39873.1 - 0.07 12.5 0.1 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KEZ39873.1 - 0.071 12.8 0.2 1.5 8.5 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_15 PF13175.1 KEZ39873.1 - 0.071 12.1 0.0 10 5.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.10 KEZ39873.1 - 0.14 10.8 0.0 4.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 KEZ39873.1 - 0.18 11.3 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 KEZ39873.1 - 0.2 10.4 0.7 4.9 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain p450 PF00067.17 KEZ39874.1 - 2.6e-55 187.7 0.0 3.4e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KEZ39875.1 - 7.7e-09 34.8 0.1 1.3e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phosphoesterase PF04185.9 KEZ39876.1 - 9.3e-30 104.0 0.4 2.7e-25 89.3 0.1 2.0 2 0 0 2 2 2 2 Phosphoesterase family Fungal_trans PF04082.13 KEZ39878.1 - 1.1e-08 34.3 0.1 1.7e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain BT1 PF03092.11 KEZ39878.1 - 0.02 13.6 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 BT1 family FAD_binding_3 PF01494.14 KEZ39879.1 - 7.2e-19 68.0 0.1 2.8e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ39879.1 - 6.2e-07 28.6 0.6 0.00082 18.3 0.8 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ39879.1 - 0.00015 21.7 0.8 0.00038 20.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ39879.1 - 0.00052 18.9 1.0 0.001 18.0 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KEZ39879.1 - 0.0013 17.4 0.1 0.0076 14.9 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KEZ39879.1 - 0.0023 17.8 0.5 0.0045 16.9 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ39879.1 - 0.0062 15.4 0.7 0.013 14.4 0.5 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KEZ39879.1 - 0.01 16.2 0.4 0.028 14.8 0.2 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ39879.1 - 0.026 13.6 2.0 0.038 13.0 1.4 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ39879.1 - 0.034 13.0 0.1 5.8 5.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 KEZ39879.1 - 0.037 12.5 0.6 0.072 11.5 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.16 KEZ39879.1 - 0.12 11.9 0.5 0.36 10.3 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 KEZ39879.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase MFS_1 PF07690.11 KEZ39880.1 - 2.8e-25 88.8 46.7 5.2e-22 78.0 27.3 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ39880.1 - 4.1e-21 74.8 23.1 6.4e-21 74.1 16.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEZ39880.1 - 2.2e-10 39.6 3.8 2.2e-10 39.6 2.7 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.7 KEZ39880.1 - 0.027 14.4 0.3 0.2 11.6 0.0 2.6 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Caps_synth_CapC PF14102.1 KEZ39880.1 - 3.7 7.6 17.0 0.58 10.2 4.9 3.1 2 1 1 3 3 3 0 Capsule biosynthesis CapC Sugar_tr PF00083.19 KEZ39882.1 - 2.3e-85 286.8 18.7 2.9e-85 286.5 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ39882.1 - 2.2e-34 118.7 40.8 5.9e-28 97.5 15.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.2 KEZ39882.1 - 3.4 7.5 19.0 0.12 12.2 6.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) UPF0075 PF03702.9 KEZ39883.1 - 2e-86 290.1 0.0 2.3e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) BcrAD_BadFG PF01869.15 KEZ39883.1 - 0.014 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF768 PF05589.6 KEZ39883.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF768) MFS_1 PF07690.11 KEZ39884.1 - 6.9e-36 123.6 22.2 6.9e-36 123.6 15.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Patatin PF01734.17 KEZ39886.1 - 1.7e-27 96.6 0.1 4.3e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_29 PF13555.1 KEZ39886.1 - 0.00068 19.1 0.1 0.0038 16.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEZ39886.1 - 0.0018 18.5 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter zf-C3HC4_2 PF13923.1 KEZ39886.1 - 0.0052 16.7 22.4 0.11 12.5 5.9 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) MobB PF03205.9 KEZ39886.1 - 0.0056 16.3 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B zf-C3HC4_4 PF15227.1 KEZ39886.1 - 0.011 15.6 14.0 0.36 10.7 0.6 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING MMR_HSR1 PF01926.18 KEZ39886.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 KEZ39886.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 KEZ39886.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 KEZ39886.1 - 0.031 13.3 0.0 0.081 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 KEZ39886.1 - 0.033 14.5 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 KEZ39886.1 - 0.039 13.7 20.1 0.21 11.4 5.8 2.7 2 0 0 2 2 2 0 Ring finger domain DUF258 PF03193.11 KEZ39886.1 - 0.05 12.7 0.1 0.17 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KEZ39886.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEZ39886.1 - 0.11 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 KEZ39886.1 - 0.12 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein T2SE PF00437.15 KEZ39886.1 - 0.19 10.5 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-RING_5 PF14634.1 KEZ39886.1 - 0.19 11.4 17.2 0.015 15.0 4.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain AAA_15 PF13175.1 KEZ39886.1 - 0.31 10.0 0.0 0.45 9.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FYVE PF01363.16 KEZ39886.1 - 2.3 8.1 8.7 3.5 7.5 0.7 2.8 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_UBOX PF13445.1 KEZ39886.1 - 7.4 6.3 10.5 0.5 10.1 1.0 3.0 2 1 1 3 3 3 0 RING-type zinc-finger p450 PF00067.17 KEZ39888.1 - 4.6e-60 203.4 0.0 6e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cys_rich_FGFR PF00839.12 KEZ39888.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Cysteine rich repeat NDK PF00334.14 KEZ39889.1 - 2.5e-55 185.9 0.0 3.2e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 KEZ39890.1 - 4.5e-23 81.0 0.0 6.6e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA MARVEL PF01284.18 KEZ39891.1 - 0.0073 16.1 12.2 0.0073 16.1 8.4 1.5 2 0 0 2 2 2 1 Membrane-associating domain FA_hydroxylase PF04116.8 KEZ39891.1 - 0.016 15.6 3.8 0.02 15.2 2.6 1.4 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily E1-E2_ATPase PF00122.15 KEZ39891.1 - 0.026 13.5 1.8 0.048 12.7 1.2 1.4 1 0 0 1 1 1 0 E1-E2 ATPase FA_desaturase PF00487.19 KEZ39891.1 - 1.1 8.6 11.3 1.4 8.2 7.9 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Herpes_LMP1 PF05297.6 KEZ39891.1 - 1.5 7.7 7.7 1.6 7.5 5.4 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Glyco_hydro_31 PF01055.21 KEZ39892.1 - 3.6e-157 523.7 3.8 5.5e-157 523.1 2.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 RmlD_sub_bind PF04321.12 KEZ39892.1 - 4.7e-52 176.6 0.0 8.7e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Gal_mutarotas_2 PF13802.1 KEZ39892.1 - 4.6e-21 74.4 0.1 1.4e-20 72.8 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Epimerase PF01370.16 KEZ39892.1 - 1.1e-18 67.5 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEZ39892.1 - 5.1e-10 38.7 0.0 1.6e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KEZ39892.1 - 3.8e-08 32.3 0.0 6.8e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEZ39892.1 - 7.8e-05 21.7 0.1 0.0012 17.8 0.0 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KEZ39892.1 - 0.002 18.1 0.1 0.0054 16.7 0.1 1.8 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEZ39892.1 - 0.18 11.6 0.8 2.1 8.2 0.6 2.3 1 1 0 1 1 1 0 short chain dehydrogenase polyprenyl_synt PF00348.12 KEZ39894.1 - 2.4e-67 226.5 0.0 2.8e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Dak2 PF02734.12 KEZ39895.1 - 0.11 12.2 0.0 5.2 6.7 0.0 2.6 3 0 0 3 3 3 0 DAK2 domain DUF4404 PF14357.1 KEZ39895.1 - 0.14 12.5 3.3 4.7 7.7 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) BTB PF00651.26 KEZ39896.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain APC8 PF04049.8 KEZ39897.1 - 1e-47 161.4 1.1 4e-47 159.5 0.1 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KEZ39897.1 - 1.5e-23 81.3 8.1 7.1e-05 22.2 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ39897.1 - 2e-21 75.4 8.2 6.9e-09 35.2 0.2 6.6 4 1 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 KEZ39897.1 - 4e-19 66.9 5.2 0.00026 20.5 0.0 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ39897.1 - 7.5e-14 50.4 22.5 0.028 14.3 0.0 8.8 10 0 0 10 10 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ39897.1 - 2.8e-13 49.2 8.6 0.025 15.2 0.0 8.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ39897.1 - 5.2e-13 48.7 13.2 7.9e-05 22.5 0.2 6.4 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ39897.1 - 2.8e-10 40.5 9.9 1.8e-05 25.2 0.2 7.4 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ39897.1 - 3.6e-10 38.8 6.4 0.091 12.5 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KEZ39897.1 - 5.9e-07 29.5 7.4 0.045 13.8 0.0 6.1 5 1 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KEZ39897.1 - 2.5e-05 24.5 7.2 13 6.1 0.0 6.8 6 2 3 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ39897.1 - 5.1e-05 23.0 13.8 1.6 8.6 0.2 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ39897.1 - 0.0004 20.6 18.5 10 6.8 0.1 8.7 9 2 1 10 10 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ39897.1 - 0.00046 20.1 0.1 1.9 8.8 0.0 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 KEZ39897.1 - 0.0091 15.8 1.5 0.5 10.1 0.1 3.4 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_15 PF13429.1 KEZ39897.1 - 0.011 14.8 4.6 0.013 14.5 0.8 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2424 PF10340.4 KEZ39897.1 - 0.047 12.3 0.0 0.075 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Fis1_TPR_C PF14853.1 KEZ39897.1 - 0.055 13.3 1.0 14 5.6 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 KEZ39897.1 - 0.1 11.3 0.0 1 8.0 0.0 2.0 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 KEZ39897.1 - 2.1 8.4 12.2 1.2 9.2 0.1 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 KEZ39898.1 - 8e-13 48.1 0.0 3e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39898.1 - 2.2e-09 36.7 0.0 1.9e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEZ39898.1 - 0.0023 17.6 0.3 0.16 11.6 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEZ39898.1 - 0.0031 16.3 0.0 0.0058 15.5 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 KEZ39898.1 - 0.11 11.2 0.0 12 4.5 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Vps54 PF07928.7 KEZ39899.1 - 1.3e-45 154.8 0.1 4.4e-45 153.1 0.0 2.0 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KEZ39899.1 - 5.3e-07 28.8 0.1 1.1e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 KEZ39899.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.6 KEZ39899.1 - 0.13 12.1 1.2 1.1 9.1 0.5 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCM PF00493.18 KEZ39900.1 - 5.2e-142 472.5 0.9 7e-142 472.0 0.6 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEZ39900.1 - 2e-19 70.2 0.5 4.9e-19 68.9 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEZ39900.1 - 7.3e-07 28.5 0.0 0.0002 20.5 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEZ39900.1 - 2e-05 24.3 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEZ39900.1 - 0.0003 20.4 0.0 0.0012 18.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEZ39900.1 - 0.043 13.2 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 KEZ39900.1 - 0.058 13.8 1.5 0.13 12.7 0.4 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Nop16 PF09420.5 KEZ39901.1 - 6.2e-51 172.7 6.2 8.4e-51 172.3 4.3 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Spt5_N PF11942.3 KEZ39901.1 - 2.6 8.7 14.0 6.4 7.4 9.7 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal MARVEL PF01284.18 KEZ39902.1 - 1.4e-05 24.9 9.0 2.4e-05 24.1 6.3 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 KEZ39902.1 - 0.02 14.9 2.4 0.042 13.9 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) DUF202 PF02656.10 KEZ39902.1 - 0.9 9.8 3.6 15 5.8 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 KEZ39903.1 - 6.3e-40 136.9 45.9 6.3e-40 136.9 31.8 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ39903.1 - 3.4e-14 52.2 14.0 3.4e-14 52.2 9.7 3.4 2 1 1 4 4 4 2 Sugar (and other) transporter MFS_1_like PF12832.2 KEZ39903.1 - 0.0037 17.0 1.2 0.016 14.9 0.1 2.6 2 0 0 2 2 2 1 MFS_1 like family GATase_2 PF00310.16 KEZ39904.1 - 3e-18 65.6 0.0 2.4e-16 59.3 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KEZ39904.1 - 4.7e-15 55.7 0.0 1e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KEZ39904.1 - 1.8e-13 50.3 0.0 2.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KEZ39904.1 - 4.4e-13 49.0 0.0 9.4e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DAO PF01266.19 KEZ39905.1 - 9.3e-59 199.1 1.9 2.1e-58 197.9 1.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ39905.1 - 1.3e-05 25.5 0.2 0.035 14.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ39905.1 - 0.00017 21.5 0.0 0.00043 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEZ39905.1 - 0.0006 18.5 0.3 0.0093 14.6 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.14 KEZ39905.1 - 0.015 14.3 0.1 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.10 KEZ39905.1 - 0.081 11.0 0.0 2.7 6.0 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 KEZ39905.1 - 0.084 11.6 0.8 0.36 9.6 0.5 1.9 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KEZ39905.1 - 0.086 12.7 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KEZ39905.1 - 0.17 11.0 0.1 11 5.0 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase GSHPx PF00255.14 KEZ39906.1 - 4.8e-41 138.4 0.0 6e-41 138.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KEZ39906.1 - 0.00018 21.1 0.1 0.00032 20.3 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEZ39906.1 - 0.001 18.6 0.1 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF4174 PF13778.1 KEZ39906.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Fungal_trans_2 PF11951.3 KEZ39907.1 - 1.2e-51 175.5 8.3 1.6e-30 106.0 1.2 2.5 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ39907.1 - 2.7e-06 27.1 6.6 6.8e-06 25.9 4.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.12 KEZ39908.1 - 3.6e-32 107.6 14.2 0.00026 20.6 0.0 10.3 11 0 0 11 11 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KEZ39908.1 - 5.5e-30 103.3 14.5 5.3e-21 74.5 0.1 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KEZ39908.1 - 2.2e-29 99.8 5.7 2e-05 23.9 0.3 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ39908.1 - 3e-28 97.2 19.1 7e-08 32.0 0.2 8.1 5 2 4 9 9 9 9 TPR repeat TPR_19 PF14559.1 KEZ39908.1 - 7.1e-24 83.9 14.1 0.0034 17.6 0.0 8.7 6 3 3 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ39908.1 - 1.8e-22 79.0 16.9 2.3e-07 30.6 0.0 8.7 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ39908.1 - 9.3e-20 69.3 20.0 0.0017 18.8 0.2 10.5 4 2 7 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ39908.1 - 3.6e-19 68.9 22.9 4.1e-09 36.8 2.2 7.9 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ39908.1 - 2.5e-17 61.2 0.0 0.0021 17.7 0.1 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ39908.1 - 3.8e-11 41.9 11.3 0.41 10.5 0.0 8.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ39908.1 - 4.3e-11 42.3 14.1 0.071 13.0 0.5 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ39908.1 - 2.8e-10 39.9 6.3 0.47 11.0 0.1 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ39908.1 - 5.7e-08 32.4 7.2 1.3 9.6 0.1 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ39908.1 - 2.6e-07 30.3 8.9 0.0016 18.2 0.1 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ39908.1 - 6.3e-06 25.9 0.5 4.1 7.8 0.0 7.4 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ39908.1 - 6.4e-05 22.1 4.8 0.071 12.1 0.0 5.2 3 2 2 6 6 6 1 Tetratricopeptide repeat DUF1347 PF07079.6 KEZ39908.1 - 0.014 13.6 0.0 0.027 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) Sel1 PF08238.7 KEZ39908.1 - 0.014 15.9 3.7 23 5.7 0.0 4.2 3 0 0 3 3 3 0 Sel1 repeat RPN7 PF10602.4 KEZ39908.1 - 0.55 9.5 4.8 1.1 8.6 0.0 3.5 4 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 KEZ39908.1 - 0.7 9.8 12.8 9.7 6.1 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA PF00004.24 KEZ39909.1 - 1.6e-28 99.5 0.0 3.6e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ39909.1 - 4.8e-05 23.5 0.1 0.02 15.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KEZ39909.1 - 0.00033 20.5 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ39909.1 - 0.00034 21.4 0.2 0.0011 19.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KEZ39909.1 - 0.0046 16.3 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KEZ39909.1 - 0.0093 16.1 0.1 0.032 14.3 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_16 PF13191.1 KEZ39909.1 - 0.011 15.6 0.3 0.24 11.3 0.2 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 KEZ39909.1 - 0.013 15.2 0.1 0.037 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEZ39909.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEZ39909.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEZ39909.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEZ39909.1 - 0.036 13.4 0.4 0.16 11.3 0.2 2.0 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KEZ39909.1 - 0.042 13.4 0.4 0.11 12.0 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ39909.1 - 0.047 13.4 0.7 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 KEZ39909.1 - 0.07 12.1 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KEZ39909.1 - 0.084 12.0 0.2 0.2 10.7 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 KEZ39910.1 - 6.4e-30 104.0 0.0 1.6e-16 60.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEZ39910.1 - 4e-09 36.0 0.9 0.00073 19.2 0.0 3.6 3 0 0 3 3 3 2 Part of AAA domain AAA_22 PF13401.1 KEZ39910.1 - 1.3e-07 31.8 0.7 0.39 10.8 0.0 4.6 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEZ39910.1 - 1.7e-07 32.0 9.1 7.5e-05 23.5 0.0 4.0 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.9 KEZ39910.1 - 1.1e-06 28.4 0.1 0.045 13.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KEZ39910.1 - 1.6e-06 27.6 0.1 0.00073 18.9 0.0 2.8 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KEZ39910.1 - 8.3e-06 25.9 0.0 0.03 14.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 KEZ39910.1 - 8.6e-06 24.9 0.0 0.15 11.1 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KEZ39910.1 - 9.2e-06 24.9 0.0 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KEZ39910.1 - 1.8e-05 24.6 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KEZ39910.1 - 3.8e-05 23.3 0.3 0.093 12.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KEZ39910.1 - 4.9e-05 23.3 0.2 0.39 10.6 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 KEZ39910.1 - 0.0003 21.0 9.0 0.019 15.2 0.0 4.1 3 1 0 3 3 2 2 AAA domain Sigma54_activ_2 PF14532.1 KEZ39910.1 - 0.00035 20.6 0.0 0.0078 16.2 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KEZ39910.1 - 0.00035 20.7 0.0 0.27 11.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KEZ39910.1 - 0.00083 19.2 0.1 1.3 8.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KEZ39910.1 - 0.001 18.7 7.1 0.39 10.2 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 KEZ39910.1 - 0.0014 18.2 0.1 2.1 7.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 KEZ39910.1 - 0.0032 16.9 0.0 2.3 7.6 0.0 3.7 3 1 0 3 3 3 1 Sigma-54 interaction domain PEPCK_ATP PF01293.15 KEZ39910.1 - 0.013 14.0 0.0 0.098 11.1 0.0 2.3 3 0 0 3 3 3 0 Phosphoenolpyruvate carboxykinase Torsin PF06309.6 KEZ39910.1 - 0.019 14.8 0.0 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 Torsin PRK PF00485.13 KEZ39910.1 - 0.035 13.6 0.0 13 5.3 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 KEZ39910.1 - 0.11 12.0 0.1 32 4.1 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.1 KEZ39910.1 - 0.2 11.0 3.2 3.8 6.8 0.1 3.5 2 1 1 3 3 3 0 AAA domain DUF3987 PF13148.1 KEZ39910.1 - 0.23 9.9 0.0 0.23 9.9 0.0 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3987) Metallophos PF00149.23 KEZ39911.1 - 1.9e-06 27.4 1.0 3e-05 23.5 0.7 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase E1-E2_ATPase PF00122.15 KEZ39912.1 - 1.7e-16 59.9 0.0 6e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ39912.1 - 2.8e-15 57.3 0.0 1.1e-14 55.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ39912.1 - 6.1e-10 39.5 0.0 1.7e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ39912.1 - 0.00024 20.9 0.0 0.0008 19.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEZ39912.1 - 0.0016 18.0 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rep_fac_C PF08542.6 KEZ39913.1 - 2.5e-19 69.0 0.0 5.2e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 KEZ39913.1 - 1e-11 45.1 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KEZ39913.1 - 3.9e-11 42.8 0.0 3e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KEZ39913.1 - 1.9e-07 31.0 0.0 4.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ39913.1 - 4.7e-07 29.9 0.0 5.9e-06 26.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KEZ39913.1 - 3.6e-06 26.1 0.0 1.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEZ39913.1 - 4e-06 27.0 0.1 0.0015 18.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 KEZ39913.1 - 2.7e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KEZ39913.1 - 2.7e-05 23.0 0.0 0.015 14.0 0.0 2.4 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 KEZ39913.1 - 3.8e-05 23.2 0.0 7.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KEZ39913.1 - 0.00096 18.6 0.0 0.12 11.7 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 KEZ39913.1 - 0.0011 18.1 0.1 0.0077 15.4 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 KEZ39913.1 - 0.0016 17.2 0.0 0.0033 16.2 0.0 1.5 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 KEZ39913.1 - 0.0021 17.8 0.3 0.0087 15.7 0.0 2.1 2 1 1 3 3 2 1 NTPase FtsK_SpoIIIE PF01580.13 KEZ39913.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DNA_pol3_delta PF06144.8 KEZ39913.1 - 0.0028 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 KEZ39913.1 - 0.0036 17.0 0.0 0.0088 15.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEZ39913.1 - 0.0053 17.0 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KEZ39913.1 - 0.0072 15.8 0.1 0.22 10.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase KTI12 PF08433.5 KEZ39913.1 - 0.013 14.6 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 KEZ39913.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEZ39913.1 - 0.025 14.0 0.1 1.5 8.1 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 KEZ39913.1 - 0.06 13.0 0.1 1.4 8.6 0.0 2.7 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_31 PF13614.1 KEZ39913.1 - 0.071 13.0 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ39913.1 - 0.08 13.1 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KEZ39913.1 - 0.091 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 KEZ39913.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.3 KEZ39913.1 - 0.11 12.2 0.3 2 8.1 0.0 2.7 3 1 1 4 4 4 0 DNA polymerase III subunits gamma and tau domain III DER1 PF04511.10 KEZ39914.1 - 3.2e-20 72.4 4.5 3.7e-20 72.2 3.1 1.0 1 0 0 1 1 1 1 Der1-like family CN_hydrolase PF00795.17 KEZ39917.1 - 2e-14 53.3 0.0 3.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Hint_2 PF13403.1 KEZ39919.1 - 8.6e-07 28.9 0.2 1.8e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 Hint domain MFS_1 PF07690.11 KEZ39919.1 - 0.00016 20.5 0.8 0.00032 19.5 0.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TcdA_TcdB_pore PF12920.2 KEZ39919.1 - 0.35 8.7 0.4 0.56 8.0 0.3 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain SNF2_N PF00176.18 KEZ39921.1 - 3.3e-12 45.8 0.0 6.1e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ39921.1 - 8.2e-05 22.3 0.3 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ39921.1 - 0.00098 18.9 0.0 0.0046 16.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3208 PF11482.3 KEZ39921.1 - 0.064 13.3 0.3 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) DKCLD PF08068.7 KEZ39922.1 - 1.2e-28 98.7 0.1 7.1e-28 96.3 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KEZ39922.1 - 9e-25 87.5 0.1 9.7e-22 77.7 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KEZ39922.1 - 5.3e-21 74.1 0.2 1.1e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 PUA domain AAA_16 PF13191.1 KEZ39923.1 - 1.9e-07 31.2 0.5 1.7e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KEZ39923.1 - 0.00035 20.2 0.0 0.0007 19.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ39923.1 - 0.0013 18.9 0.2 0.0069 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KEZ39923.1 - 0.0064 15.4 0.0 0.018 13.9 0.0 1.7 1 1 1 2 2 2 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KEZ39923.1 - 0.0071 15.2 0.0 0.0071 15.2 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain PPV_E1_C PF00519.12 KEZ39923.1 - 0.033 12.8 0.4 0.053 12.1 0.0 1.6 2 0 0 2 2 2 0 Papillomavirus helicase TrwB_AAD_bind PF10412.4 KEZ39923.1 - 0.037 12.6 0.1 0.81 8.2 0.0 2.2 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 KEZ39923.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KEZ39924.1 - 1.3e-37 129.2 0.0 2.3e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ39924.1 - 0.0049 16.6 0.0 0.37 10.6 0.0 2.5 1 1 1 2 2 2 2 Helicase conserved C-terminal domain SKG6 PF08693.5 KEZ39925.1 - 0.043 13.1 0.9 0.1 11.8 0.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PAT1 PF09770.4 KEZ39925.1 - 5 5.2 14.8 6.7 4.8 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAC3_GANP PF03399.11 KEZ39926.1 - 4.2e-43 147.2 0.0 6.5e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEZ39926.1 - 0.0011 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 LTV PF04180.9 KEZ39927.1 - 1.7e-106 357.2 12.0 2e-106 357.0 8.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein YL1 PF05764.8 KEZ39927.1 - 2.2 7.8 8.1 4.2 6.9 5.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein MMR_HSR1 PF01926.18 KEZ39928.1 - 5.9e-17 61.7 0.2 6.3e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ39928.1 - 3e-06 26.6 0.2 2.7e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KEZ39928.1 - 0.00021 20.5 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEZ39928.1 - 0.0038 17.0 1.1 0.15 11.8 0.2 2.7 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.11 KEZ39928.1 - 0.0075 15.4 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KEZ39928.1 - 0.035 14.5 0.0 0.082 13.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Acyl-CoA_dh_1 PF00441.19 KEZ39929.1 - 3.6e-28 98.5 0.4 7e-28 97.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ39929.1 - 1.1e-16 60.0 0.0 2.5e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEZ39929.1 - 5.3e-14 52.6 1.5 9e-14 51.8 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEZ39929.1 - 5e-13 49.6 0.1 1.1e-12 48.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Spo12 PF05032.7 KEZ39930.1 - 5e-15 54.8 0.1 1.2e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Spo12 family TGS PF02824.16 KEZ39931.1 - 1e-19 70.1 0.1 1.8e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KEZ39931.1 - 2.3e-10 40.4 0.0 8.6e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ39931.1 - 0.00025 20.3 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEZ39931.1 - 0.00064 19.5 0.1 0.0014 18.4 0.0 1.5 2 0 0 2 2 2 1 Dynamin family RRM_1 PF00076.17 KEZ39932.1 - 5.4e-08 32.3 0.0 9.6e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ39932.1 - 1.1e-07 31.5 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ39932.1 - 4.2e-05 23.2 0.0 8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KEZ39932.1 - 0.00017 21.5 0.1 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KEZ39932.1 - 0.0049 16.5 0.5 0.01 15.5 0.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cut12 PF11500.3 KEZ39933.1 - 3.2e-42 143.7 16.5 3.2e-42 143.7 11.4 3.9 4 1 1 5 5 5 1 Spindle pole body formation-associated protein UreF PF01730.11 KEZ39933.1 - 9.6e-15 54.9 0.0 9.6e-15 54.9 0.0 2.3 2 1 0 2 2 2 1 UreF Spectrin PF00435.16 KEZ39933.1 - 0.0035 17.6 0.9 0.0035 17.6 0.6 3.9 2 2 1 3 3 3 2 Spectrin repeat Pkinase PF00069.20 KEZ39934.1 - 4.3e-66 222.7 0.1 1.1e-33 116.4 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39934.1 - 5.3e-48 163.3 0.0 8.3e-21 74.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 KEZ39934.1 - 5.2e-47 160.2 0.0 5.2e-47 160.2 0.0 3.0 3 1 0 3 3 3 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 KEZ39934.1 - 1.8e-15 56.7 0.4 4.2e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 KEZ39934.1 - 1.8e-12 47.1 0.1 3.8e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 RWD domain APH PF01636.18 KEZ39934.1 - 1.1e-07 31.8 3.8 0.0018 18.0 0.0 2.9 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEZ39934.1 - 0.00036 19.5 0.0 0.015 14.2 0.0 2.6 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEZ39934.1 - 0.0022 17.3 0.0 0.34 10.2 0.0 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 KEZ39934.1 - 0.12 11.1 0.1 12 4.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UQ_con PF00179.21 KEZ39935.1 - 1.2e-33 115.4 0.0 1.5e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ39935.1 - 0.0044 16.7 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEZ39935.1 - 0.034 14.0 0.4 0.066 13.1 0.3 1.9 1 1 0 1 1 1 0 RWD domain Acetyltransf_11 PF13720.1 KEZ39936.1 - 0.066 13.4 0.3 4 7.7 0.1 3.5 4 0 0 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DnaJ PF00226.26 KEZ39937.1 - 6.6e-27 93.0 1.5 1.1e-26 92.3 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEZ39937.1 - 8.5e-24 83.2 1.7 1.9e-22 78.9 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain HAD_2 PF13419.1 KEZ39938.1 - 1.7e-16 60.9 0.0 2.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ39938.1 - 2.5e-07 30.3 0.0 5.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEZ39938.1 - 3.3e-07 30.9 0.1 3.5e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KEZ39938.1 - 0.00057 19.5 0.0 0.067 12.8 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Rod_cone_degen PF15201.1 KEZ39939.1 - 0.83 9.5 0.1 0.83 9.5 0.1 2.8 3 0 0 3 3 3 0 Progressive rod-cone degeneration FH2 PF02181.18 KEZ39940.1 - 7.2e-82 275.2 5.0 7.2e-82 275.2 3.5 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KEZ39940.1 - 2.1e-64 216.3 0.2 1.1e-63 213.9 0.0 2.5 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KEZ39940.1 - 8.1e-52 175.4 3.4 5.5e-51 172.7 2.4 2.4 1 1 0 1 1 1 1 Diaphanous FH3 Domain DUF4048 PF13257.1 KEZ39941.1 - 1.7e-10 40.9 10.1 1.7e-10 40.9 7.0 3.5 2 2 0 3 3 3 1 Domain of unknown function (DUF4048) DNA_ligase_A_N PF04675.9 KEZ39942.1 - 6.3e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 KEZ39942.1 - 0.00017 20.9 0.0 0.24 10.7 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain Pkinase PF00069.20 KEZ39943.1 - 4.4e-69 232.5 0.0 9.4e-69 231.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39943.1 - 3.6e-35 121.2 0.0 1e-34 119.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ39943.1 - 0.00015 20.8 0.1 0.00032 19.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ39943.1 - 0.0024 16.9 0.1 0.0053 15.8 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 KEZ39944.1 - 6.5e-12 45.8 0.0 9.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ39944.1 - 1.7e-11 44.1 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ39944.1 - 6.6e-06 25.9 0.0 1.5e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF150 PF02576.12 KEZ39944.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 Utp11 PF03998.8 KEZ39945.1 - 0.096 12.4 16.3 0.13 12.0 11.3 1.2 1 0 0 1 1 1 0 Utp11 protein Cut8_N PF14482.1 KEZ39945.1 - 0.58 10.2 10.0 0.72 9.8 2.3 3.0 2 1 0 2 2 2 0 Cut8 proteasome-binding domain YgaB PF14182.1 KEZ39945.1 - 2.5 8.4 9.6 2.3 8.5 5.2 2.0 1 1 1 2 2 2 0 YgaB-like protein Skp1 PF01466.14 KEZ39945.1 - 2.5 8.1 5.9 4.1 7.4 3.1 2.0 1 1 1 2 2 2 0 Skp1 family, dimerisation domain RR_TM4-6 PF06459.7 KEZ39945.1 - 3.1 7.6 13.9 3.8 7.3 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IF4E PF01652.13 KEZ39946.1 - 2.7e-52 176.6 0.1 3.7e-52 176.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1917 PF08939.5 KEZ39946.1 - 0.14 11.8 3.7 0.048 13.4 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) WD40 PF00400.27 KEZ39947.1 - 4.1e-69 226.1 30.1 5e-09 35.7 0.0 12.1 11 2 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KEZ39947.1 - 1.3e-43 147.9 0.8 2.1e-43 147.3 0.6 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 KEZ39947.1 - 4.1e-09 35.6 7.4 0.0024 16.6 0.1 5.3 6 0 0 6 6 6 4 Nup133 N terminal like Nup160 PF11715.3 KEZ39947.1 - 1.5e-07 30.0 11.9 0.018 13.2 0.1 6.4 5 2 2 7 7 7 4 Nucleoporin Nup120/160 COX7a PF02238.10 KEZ39948.1 - 0.08 12.6 0.2 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Malic_M PF03949.10 KEZ39949.1 - 7.4e-87 291.1 0.0 9.8e-87 290.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KEZ39949.1 - 1.6e-69 233.1 0.0 2.6e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RNB PF00773.14 KEZ39950.1 - 3.4e-76 256.6 0.0 8.9e-76 255.2 0.0 1.8 2 0 0 2 2 2 1 RNB domain DUF4239 PF14023.1 KEZ39950.1 - 0.035 13.4 0.2 0.09 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ferritin_2 PF13668.1 KEZ39951.1 - 2e-40 137.8 1.7 2.8e-40 137.4 0.6 1.6 2 0 0 2 2 2 1 Ferritin-like domain DIOX_N PF14226.1 KEZ39952.1 - 3.2e-17 63.1 0.0 5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEZ39952.1 - 2.3e-13 50.2 0.0 7.2e-13 48.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 KEZ39953.1 - 1.8e-61 207.2 0.0 2.5e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KEZ39953.1 - 3.9e-28 97.6 0.1 8.8e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 KEZ39953.1 - 1.3e-06 28.5 0.0 1.3e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KEZ39953.1 - 0.0032 17.4 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region Pmp3 PF01679.12 KEZ39954.1 - 9.4e-09 34.8 15.6 7.3e-07 28.8 10.8 2.1 1 1 0 1 1 1 1 Proteolipid membrane potential modulator zf-RanBP PF00641.13 KEZ39955.1 - 9.4e-19 66.2 12.9 3.5e-11 42.0 1.0 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KEZ39955.1 - 9.5e-09 34.7 0.0 1.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 KEZ39955.1 - 6.2e-06 26.6 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 KEZ39955.1 - 7.2e-06 25.8 0.0 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 KEZ39955.1 - 4.1 7.3 11.1 0.79 9.5 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.27 KEZ39956.1 - 2.3e-39 131.8 3.4 8.3e-10 38.1 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KEZ39956.1 - 8.1e-30 102.5 0.2 1.9e-29 101.3 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex XRN_N PF03159.13 KEZ39957.1 - 3e-101 337.7 0.0 5e-101 337.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SPC22 PF04573.7 KEZ39958.1 - 2e-33 115.1 0.0 6.8e-25 87.3 0.0 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Cohesin_load PF10345.4 KEZ39960.1 - 8.6e-129 430.5 1.9 1.2e-128 430.0 1.3 1.2 1 0 0 1 1 1 1 Cohesin loading factor Apc3 PF12895.2 KEZ39960.1 - 0.039 14.0 0.5 0.19 11.8 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HDA2-3 PF11496.3 KEZ39961.1 - 6e-13 48.2 0.4 1.8e-12 46.7 0.3 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERM PF00769.14 KEZ39961.1 - 0.016 14.7 32.8 0.56 9.6 8.6 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3141 PF11339.3 KEZ39961.1 - 0.019 13.3 0.5 0.031 12.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Shugoshin_N PF07558.6 KEZ39961.1 - 0.035 13.8 3.6 0.99 9.1 0.1 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region BRE1 PF08647.6 KEZ39961.1 - 0.24 11.3 20.7 0.019 14.9 3.9 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2746 PF10874.3 KEZ39961.1 - 0.39 10.9 7.2 0.13 12.4 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) IncA PF04156.9 KEZ39961.1 - 0.53 9.8 32.4 0.031 13.8 3.6 2.7 3 0 0 3 3 3 0 IncA protein Myosin_tail_1 PF01576.14 KEZ39961.1 - 1.5 6.4 32.8 0.07 10.8 11.3 2.0 2 0 0 2 2 2 0 Myosin tail Reo_sigmaC PF04582.7 KEZ39961.1 - 1.7 7.7 6.1 7 5.7 0.3 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 KEZ39961.1 - 1.8 7.5 28.8 1.8 7.5 4.2 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 KEZ39961.1 - 2 8.7 18.0 2.6 8.4 3.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) MCPsignal PF00015.16 KEZ39961.1 - 3.2 7.2 12.1 0.51 9.8 1.8 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF745 PF05335.8 KEZ39961.1 - 8.4 5.8 19.3 0.5 9.8 7.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF745) COX5A PF02284.11 KEZ39962.1 - 7.4e-38 128.8 1.7 1.2e-37 128.1 1.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va THP2 PF09432.5 KEZ39962.1 - 0.059 13.2 0.4 0.15 11.8 0.2 1.7 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF1804 PF08822.6 KEZ39962.1 - 0.061 13.0 0.2 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF3007 PF11460.3 KEZ39962.1 - 0.17 11.9 0.5 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) ELO PF01151.13 KEZ39963.1 - 4.7e-64 216.0 15.5 5.5e-64 215.8 10.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.2 KEZ39964.1 - 6.6e-05 22.5 0.8 0.00028 20.5 0.6 2.1 1 0 0 1 1 1 1 F-box-like Glycogen_syn PF05693.8 KEZ39965.1 - 0 1112.7 0.0 0 1112.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KEZ39965.1 - 3.6e-06 26.4 0.0 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KEZ39965.1 - 1.4e-05 24.7 0.1 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KEZ39965.1 - 4.8e-05 23.5 0.1 0.00033 20.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Hid1 PF12722.2 KEZ39966.1 - 3.7e-245 815.7 0.0 2e-244 813.3 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KEZ39966.1 - 1.3e-72 244.9 0.0 1.9e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 KEZ39968.1 - 2e-31 108.7 0.0 3.6e-31 107.9 0.0 1.4 1 1 0 1 1 1 1 Nuclear pore complex component DUF3684 PF12449.3 KEZ39969.1 - 0 1260.5 0.0 0 1260.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KEZ39969.1 - 0.00012 21.7 0.0 0.0003 20.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MMtag PF10159.4 KEZ39970.1 - 6.6e-30 102.9 3.8 6.6e-30 102.9 2.7 1.9 2 0 0 2 2 2 1 Kinase phosphorylation protein FKBP_C PF00254.23 KEZ39971.1 - 1.3e-29 102.0 0.0 3.4e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3967 PF13152.1 KEZ39971.1 - 1.6 8.4 6.1 11 5.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3967) Glyco_trans_2_3 PF13632.1 KEZ39972.1 - 1.7e-18 67.0 0.4 3.6e-18 65.9 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 FimP PF09766.4 KEZ39973.1 - 2e-27 96.1 12.3 3.3e-27 95.4 8.5 1.3 1 0 0 1 1 1 1 Fms-interacting protein Methyltransf_21 PF05050.7 KEZ39973.1 - 0.0057 16.6 0.1 0.0069 16.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF2959 PF11172.3 KEZ39973.1 - 0.055 13.2 3.0 0.11 12.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF972 PF06156.8 KEZ39973.1 - 0.32 11.3 6.5 4.2 7.7 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) K-box PF01486.12 KEZ39973.1 - 0.37 10.6 12.3 0.73 9.6 5.2 3.1 1 1 2 3 3 3 0 K-box region ERM PF00769.14 KEZ39973.1 - 0.38 10.2 16.8 1.6 8.1 5.8 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4200 PF13863.1 KEZ39973.1 - 0.49 10.3 16.0 0.49 10.3 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF349 PF03993.7 KEZ39973.1 - 2.3 8.4 10.6 0.58 10.3 4.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) ADIP PF11559.3 KEZ39973.1 - 2.4 8.0 16.0 4.7 7.0 2.7 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 KEZ39973.1 - 4.6 6.0 10.8 2.4 7.0 5.8 1.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KEZ39973.1 - 5.2 6.6 10.1 5.8 6.4 3.1 2.4 2 0 0 2 2 2 0 Septum formation initiator HlyIII PF03006.15 KEZ39974.1 - 8.1e-58 195.4 19.2 1e-57 195.1 13.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Planc_extracel PF07595.7 KEZ39974.1 - 0.21 11.2 3.7 0.91 9.3 0.0 2.7 2 0 0 2 2 2 0 Planctomycete extracellular Pkinase PF00069.20 KEZ39976.1 - 4e-31 108.1 0.0 4.4e-30 104.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39976.1 - 1.8e-14 53.4 0.0 3.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.19 KEZ39976.1 - 0.00024 20.6 1.3 0.00066 19.2 0.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pox_ser-thr_kin PF05445.6 KEZ39976.1 - 0.017 13.9 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RabGAP-TBC PF00566.13 KEZ39977.1 - 1.4e-32 112.9 0.1 2.5e-26 92.5 0.0 3.0 3 0 0 3 3 3 2 Rab-GTPase-TBC domain TFIIA PF03153.8 KEZ39977.1 - 0.52 10.1 12.1 0.76 9.6 5.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sulfate_transp PF00916.15 KEZ39978.1 - 5.9e-74 248.5 11.8 1.2e-73 247.5 8.2 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEZ39978.1 - 4.5e-30 103.1 4.2 4.5e-30 103.1 2.9 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEZ39978.1 - 1e-06 28.1 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain 7tm_2 PF00002.19 KEZ39979.1 - 8.7e-06 24.9 13.8 1.3e-05 24.4 7.9 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KEZ39979.1 - 0.001 18.0 8.2 0.002 17.0 5.7 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor DC_STAMP PF07782.8 KEZ39979.1 - 0.0062 16.1 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 DC-STAMP-like protein Vma12 PF11712.3 KEZ39979.1 - 0.49 10.1 5.5 9.7 5.8 1.0 3.1 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Abhydrolase_6 PF12697.2 KEZ39980.1 - 3.5e-24 85.9 2.6 4.5e-24 85.5 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ39980.1 - 8e-11 41.8 0.2 1.5e-10 41.0 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ39980.1 - 2.9e-05 23.7 0.0 0.00032 20.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KEZ39980.1 - 3.8e-05 24.0 0.1 6.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 KEZ39980.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KEZ39980.1 - 0.052 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.8 KEZ39980.1 - 0.076 11.2 0.2 2.6 6.2 0.1 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II TRP PF06011.7 KEZ39981.1 - 2.2e-130 435.1 14.4 3.2e-130 434.6 10.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEZ39981.1 - 3.3e-37 127.6 1.5 5.1e-37 127.0 1.0 1.3 1 0 0 1 1 1 1 ML-like domain SieB PF14163.1 KEZ39981.1 - 0.84 9.2 6.4 0.81 9.2 0.0 3.0 3 0 0 3 3 3 0 Superinfection exclusion protein B FtsL PF04999.8 KEZ39981.1 - 6 6.6 9.3 3.4 7.4 0.0 3.3 2 1 1 3 3 3 0 Cell division protein FtsL Asn_synthase PF00733.16 KEZ39982.1 - 8.4e-51 172.9 0.0 1.2e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KEZ39982.1 - 5.1e-08 32.7 0.0 3.1e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KEZ39982.1 - 0.00015 21.7 0.0 0.00036 20.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain PAPS_reduct PF01507.14 KEZ39982.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family EcsB PF05975.7 KEZ39983.1 - 0.013 14.0 2.6 0.017 13.5 1.8 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB zf-C2H2 PF00096.21 KEZ39984.1 - 0.016 15.5 2.6 0.016 15.5 1.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ39984.1 - 0.71 10.3 21.1 0.088 13.1 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger TAP_C PF03943.8 KEZ39985.1 - 1.2e-10 40.6 0.1 2.6e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 KEZ39985.1 - 4.2e-06 27.1 0.0 2.1e-05 24.8 0.0 2.2 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.2 KEZ39985.1 - 6.3e-06 25.6 0.9 0.0026 17.3 0.1 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ39985.1 - 0.063 13.0 0.4 0.19 11.4 0.2 2.0 1 1 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.28 KEZ39985.1 - 0.22 11.6 1.4 20 5.7 0.3 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.20 KEZ39986.1 - 1.5e-16 60.3 0.0 4.5e-14 52.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ39986.1 - 1.6e-05 24.0 0.0 0.00031 19.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Peroxidase_2 PF01328.12 KEZ39987.1 - 8.9e-28 96.8 1.3 8.9e-16 57.4 0.1 2.0 2 0 0 2 2 2 2 Peroxidase, family 2 Ank_2 PF12796.2 KEZ39988.1 - 2e-41 140.1 5.6 4.9e-14 52.4 0.1 5.2 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ39988.1 - 1.3e-30 103.6 13.8 0.006 16.3 0.0 11.7 11 1 1 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 KEZ39988.1 - 6.3e-29 99.8 12.2 2.3e-08 34.2 0.1 8.6 7 2 2 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ39988.1 - 1.8e-28 95.7 12.7 0.0076 16.3 0.0 11.7 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.1 KEZ39988.1 - 4.7e-14 52.0 8.3 0.0018 18.4 0.0 6.6 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Clr5 PF14420.1 KEZ39988.1 - 3.9e-10 39.4 0.1 7.7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain HET PF06985.6 KEZ39991.1 - 6.3e-28 97.6 0.0 1.2e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SseC PF04888.7 KEZ39992.1 - 0.0012 18.2 8.3 0.0023 17.3 5.7 1.4 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family EspB PF05802.6 KEZ39992.1 - 0.002 17.1 15.5 0.002 17.1 10.7 1.8 2 0 0 2 2 2 1 Enterobacterial EspB protein DUF883 PF05957.8 KEZ39992.1 - 0.021 15.1 7.0 0.58 10.6 2.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KEZ39992.1 - 0.024 14.9 7.6 51 4.3 5.3 3.3 1 1 0 1 1 1 0 YtxH-like protein Tape_meas_lam_C PF09718.5 KEZ39992.1 - 0.03 14.2 13.9 0.72 9.8 1.4 3.3 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CsbD PF05532.7 KEZ39992.1 - 0.07 12.8 10.1 0.02 14.5 3.4 2.7 2 1 1 3 3 3 0 CsbD-like HTH_15 PF12324.3 KEZ39992.1 - 0.093 12.3 11.9 0.51 10.0 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase Phasin PF05597.6 KEZ39992.1 - 0.37 10.5 2.4 0.83 9.4 1.7 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MT0933_antitox PF14013.1 KEZ39992.1 - 1.8 8.6 32.4 44 4.2 11.7 3.3 1 1 1 2 2 2 0 MT0933-like antitoxin protein ISG65-75 PF11727.3 KEZ39992.1 - 4.3 6.3 5.8 7.1 5.5 4.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein ATP_bind_1 PF03029.12 KEZ39993.1 - 7.7e-67 225.2 0.0 1.6e-66 224.2 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KEZ39993.1 - 1.4e-05 25.9 0.0 5e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEZ39993.1 - 5e-05 23.2 0.0 0.0001 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ39993.1 - 0.0023 17.8 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KEZ39993.1 - 0.0023 17.5 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEZ39993.1 - 0.0031 16.9 0.0 0.0053 16.2 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 KEZ39993.1 - 0.0039 17.3 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 KEZ39993.1 - 0.0042 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KEZ39993.1 - 0.0072 15.7 0.0 0.019 14.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 KEZ39993.1 - 0.0074 16.5 0.2 0.082 13.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_31 PF13614.1 KEZ39993.1 - 0.018 15.0 0.0 0.061 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ39993.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 KEZ39993.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KEZ39993.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEZ39993.1 - 0.024 14.9 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 KEZ39993.1 - 0.025 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 KEZ39993.1 - 0.028 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KEZ39993.1 - 0.031 13.6 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KEZ39993.1 - 0.047 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Hpr_kinase_C PF07475.7 KEZ39993.1 - 0.057 12.7 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain SRP54 PF00448.17 KEZ39993.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 KEZ39993.1 - 0.067 12.6 0.0 1.8 7.9 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KEZ39993.1 - 0.068 12.6 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation PPV_E1_C PF00519.12 KEZ39993.1 - 0.084 11.4 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Septin PF00735.13 KEZ39993.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_5 PF07728.9 KEZ39993.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KEZ39993.1 - 0.15 12.5 0.0 3 8.3 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein Adeno_IVa2 PF02456.10 KEZ39993.1 - 0.18 10.3 0.0 0.53 8.8 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein S-AdoMet_synt_C PF02773.11 KEZ39994.1 - 3.9e-76 253.3 0.1 6.9e-76 252.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KEZ39994.1 - 2.6e-46 156.4 0.0 4.8e-46 155.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KEZ39994.1 - 3.6e-41 139.4 0.4 7.2e-41 138.4 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain THF_DHG_CYH PF00763.18 KEZ39996.1 - 1.6e-18 66.8 0.1 2.2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KEZ39996.1 - 3.6e-14 52.1 0.0 1e-08 34.4 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.17 KEZ39996.1 - 0.017 13.9 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Ank_2 PF12796.2 KEZ39997.1 - 8.6e-127 413.8 0.0 8e-18 64.5 0.0 8.6 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ39997.1 - 8.8e-92 296.6 3.3 3.8e-06 26.4 0.0 17.5 17 0 0 17 17 17 16 Ankyrin repeat Ank_4 PF13637.1 KEZ39997.1 - 8.3e-87 284.1 6.4 2.5e-11 43.7 0.0 12.1 7 5 6 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ39997.1 - 2.9e-68 218.9 2.7 0.00044 20.2 0.0 18.1 18 0 0 18 18 18 14 Ankyrin repeat Ank_5 PF13857.1 KEZ39997.1 - 1.7e-65 215.5 11.8 4e-10 39.5 0.1 14.2 3 3 11 15 15 15 15 Ankyrin repeats (many copies) GTP-bdg_N PF13167.1 KEZ39997.1 - 0.039 14.0 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal PsbJ PF01788.12 KEZ39997.1 - 0.53 9.8 3.3 9.4 5.8 0.0 3.8 4 0 0 4 4 4 0 PsbJ MMS19_N PF14500.1 KEZ39998.1 - 1.3e-45 155.7 0.0 3.1e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KEZ39998.1 - 5.9e-14 51.6 0.0 4.8e-13 48.6 0.0 2.4 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal Dpoe2NT PF12213.3 KEZ39998.1 - 0.043 13.7 0.7 0.18 11.7 0.1 2.3 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal HEAT_2 PF13646.1 KEZ39998.1 - 0.07 13.4 6.5 0.39 11.0 1.9 3.5 2 1 0 2 2 2 0 HEAT repeats SPC25 PF06703.6 KEZ39999.1 - 4.3e-50 169.4 0.0 5.4e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pox_F16 PF04708.7 KEZ39999.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F16 protein DUF106 PF01956.11 KEZ40000.1 - 4.6e-53 179.2 0.6 6.8e-53 178.6 0.4 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cytochrom_B_N PF00033.14 KEZ40000.1 - 0.062 12.6 1.5 0.13 11.5 0.0 2.0 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 KEZ40000.1 - 0.13 11.6 1.2 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 RNA_pol_Rbc25 PF08292.7 KEZ40001.1 - 5.8e-30 103.9 0.0 9.1e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KEZ40001.1 - 5.6e-09 36.0 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.4 KEZ40002.1 - 1.1e-09 37.5 4.5 4.1e-09 35.7 3.1 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KEZ40002.1 - 0.14 11.8 5.7 0.28 10.9 3.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SPT2 PF08243.6 KEZ40004.1 - 3.1e-07 30.6 25.5 6.9e-06 26.3 17.7 2.3 1 1 0 1 1 1 1 SPT2 chromatin protein Metallophos PF00149.23 KEZ40005.1 - 1.6e-09 37.4 0.6 4e-09 36.1 0.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TAP42 PF04177.7 KEZ40005.1 - 0.006 15.5 1.5 0.006 15.5 1.0 2.3 2 2 0 2 2 2 1 TAP42-like family RXT2_N PF08595.6 KEZ40005.1 - 6.2 6.5 13.5 7.8 6.2 2.1 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.7 KEZ40005.1 - 7.2 4.3 30.3 3 5.6 7.3 2.1 2 0 0 2 2 2 0 Nop14-like family Ofd1_CTDD PF10637.4 KEZ40006.1 - 5.5e-99 330.6 0.0 1.8e-91 306.0 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KEZ40006.1 - 6.3e-15 55.5 0.0 1.4e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEZ40006.1 - 0.0005 19.6 0.0 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TEX19 PF15553.1 KEZ40006.1 - 2.1 8.1 7.7 3.1 7.6 3.7 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 Paf1 PF03985.8 KEZ40006.1 - 4.2 6.0 8.4 2 7.0 3.2 1.9 2 0 0 2 2 2 0 Paf1 Aminotran_5 PF00266.14 KEZ40007.1 - 1.3e-52 178.7 0.0 2.1e-52 178.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KEZ40007.1 - 7.7e-11 41.5 0.0 1.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEZ40007.1 - 7.1e-05 21.2 0.0 0.00011 20.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEZ40007.1 - 0.0033 16.5 0.1 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribul_P_3_epim PF00834.14 KEZ40008.1 - 3.9e-64 215.4 0.0 2.3e-63 212.9 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 KEZ40008.1 - 0.013 14.9 0.1 0.025 13.9 0.0 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 KEZ40008.1 - 0.03 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF2493 PF10686.4 KEZ40008.1 - 0.052 13.0 0.1 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) QRPTase_C PF01729.14 KEZ40008.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Pkinase PF00069.20 KEZ40009.1 - 4.9e-68 229.0 0.0 8.3e-68 228.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40009.1 - 3.3e-38 131.2 0.0 5.5e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ40009.1 - 3.2e-08 32.8 0.0 6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ40009.1 - 0.00076 19.2 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEZ40009.1 - 0.014 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 AAA PF00004.24 KEZ40010.1 - 1.9e-50 170.4 0.0 2e-42 144.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ40010.1 - 7.5e-05 23.5 0.0 0.00036 21.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KEZ40010.1 - 0.00018 20.6 0.0 0.00042 19.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEZ40010.1 - 0.0002 20.8 0.0 0.00096 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ40010.1 - 0.0003 20.8 0.2 0.015 15.3 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Parvo_NS1 PF01057.12 KEZ40010.1 - 0.00067 18.6 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KEZ40010.1 - 0.00082 19.5 0.0 0.0054 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEZ40010.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KEZ40010.1 - 0.0023 17.6 0.1 0.016 14.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 KEZ40010.1 - 0.0027 17.6 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KEZ40010.1 - 0.0091 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 KEZ40010.1 - 0.0098 16.0 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 KEZ40010.1 - 0.021 14.5 0.1 0.11 12.1 0.0 2.4 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KEZ40010.1 - 0.022 13.8 0.1 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KEZ40010.1 - 0.031 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 KEZ40010.1 - 0.044 13.0 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 KEZ40010.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEZ40010.1 - 0.059 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEZ40010.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KEZ40010.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 KEZ40010.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEZ40010.1 - 0.15 11.5 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KEZ40010.1 - 0.16 11.5 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KEZ40010.1 - 0.26 11.0 0.0 0.53 10.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PPV_E1_C PF00519.12 KEZ40010.1 - 0.28 9.7 0.0 0.44 9.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Peptidase_M3 PF01432.15 KEZ40011.1 - 7.9e-81 272.4 0.2 2.3e-49 168.6 0.2 2.3 1 1 1 2 2 2 2 Peptidase family M3 Methyltransf_23 PF13489.1 KEZ40012.1 - 1.9e-11 43.9 0.0 2.8e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40012.1 - 6.5e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40012.1 - 1.2e-05 25.8 0.0 2.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ40012.1 - 0.0028 16.7 0.0 0.013 14.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 KEZ40012.1 - 0.0039 17.6 0.0 0.0081 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40012.1 - 0.011 15.3 0.0 0.049 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ40012.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KEZ40012.1 - 0.037 14.0 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KEZ40012.1 - 0.048 12.7 0.0 0.17 10.9 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ40012.1 - 0.11 12.8 0.0 0.57 10.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KEZ40013.1 - 4e-63 212.9 0.0 5.5e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40013.1 - 9.4e-37 126.4 0.0 1.2e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEZ40013.1 - 2.3e-05 23.5 0.0 3.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEZ40013.1 - 2.8e-05 23.2 0.0 6.5e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEZ40013.1 - 0.0012 18.5 0.1 0.069 12.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAN_1 PF00024.21 KEZ40013.1 - 0.0082 15.8 3.0 0.016 14.9 2.1 1.4 1 0 0 1 1 1 1 PAN domain YrbL-PhoP_reg PF10707.4 KEZ40013.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PAN_4 PF14295.1 KEZ40013.1 - 0.2 11.3 4.0 0.41 10.4 2.8 1.5 1 0 0 1 1 1 0 PAN domain OTT_1508_deam PF14441.1 KEZ40014.1 - 8.6e-09 35.3 0.0 2.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Fungal_trans PF04082.13 KEZ40015.1 - 9.2e-32 109.9 0.0 1.4e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARP PF00644.15 KEZ40016.1 - 3e-58 196.6 0.0 3e-58 196.6 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KEZ40016.1 - 3.9e-42 143.0 0.0 6.8e-42 142.3 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KEZ40016.1 - 3.2e-23 81.4 0.5 8.6e-23 80.0 0.3 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 KEZ40016.1 - 1.8e-11 44.0 0.0 3.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEZ40016.1 - 1.9e-08 33.9 0.1 3.8e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain FAD_binding_4 PF01565.18 KEZ40017.1 - 2.1e-26 92.0 0.2 3.5e-26 91.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3632 PF12311.3 KEZ40018.1 - 1.5e-41 142.2 4.1 1.8e-41 141.9 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 KEZ40019.1 - 2.8e-20 72.1 0.0 4.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 ribonuclease MFS_1 PF07690.11 KEZ40020.1 - 8.6e-30 103.6 44.3 1.5e-29 102.8 29.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 KEZ40020.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Caleosin PF05042.8 KEZ40021.1 - 2.4e-46 157.4 0.1 3.2e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 KEZ40021.1 - 8.3e-05 22.1 3.2 0.0063 16.3 0.6 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KEZ40021.1 - 0.00015 20.8 3.1 0.0089 15.2 0.2 3.2 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 KEZ40021.1 - 0.0011 19.0 0.4 0.42 10.7 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 KEZ40021.1 - 0.41 10.2 2.3 1.7 8.2 0.3 2.4 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 KEZ40021.1 - 0.99 8.8 4.5 4.3 6.8 0.3 3.0 3 0 0 3 3 3 0 EF hand p450 PF00067.17 KEZ40023.1 - 3.3e-39 134.7 0.0 1.7e-22 79.6 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 Trp_DMAT PF11991.3 KEZ40024.1 - 4.7e-47 160.9 0.0 5.6e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Ferric_reduct PF01794.14 KEZ40025.1 - 1.8e-19 70.0 16.5 3.9e-19 68.9 11.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEZ40025.1 - 5.7e-07 29.5 1.4 0.0014 18.5 0.0 2.3 1 1 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEZ40025.1 - 1.5e-06 28.0 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain XPA_N PF01286.13 KEZ40027.1 - 0.56 9.9 2.6 1.1 8.9 0.3 2.2 2 0 0 2 2 2 0 XPA protein N-terminal MFS_1 PF07690.11 KEZ40028.1 - 1.3e-36 126.0 24.6 2e-36 125.4 17.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KEZ40029.1 - 1.4e-29 102.9 60.9 5.9e-23 81.1 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ40029.1 - 6.7e-05 22.6 11.9 0.0019 17.9 1.8 3.6 4 0 0 4 4 4 2 MFS_1 like family Fungal_trans PF04082.13 KEZ40030.1 - 1.6e-08 33.7 0.0 3.9e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_C PF05199.8 KEZ40031.1 - 1.3e-31 109.8 0.0 2.3e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KEZ40031.1 - 1.7e-26 93.0 0.0 3.1e-19 69.2 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.1 KEZ40031.1 - 3.9e-05 23.5 0.3 0.00012 21.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEZ40031.1 - 0.00098 19.0 0.0 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ40031.1 - 0.0036 17.3 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ40031.1 - 0.012 14.4 0.2 0.031 13.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KEZ40031.1 - 0.036 13.1 0.3 0.055 12.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KEZ40031.1 - 0.042 12.7 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2190 PF09956.4 KEZ40031.1 - 0.048 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) HI0933_like PF03486.9 KEZ40031.1 - 0.19 10.1 0.2 0.28 9.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein RGS PF00615.14 KEZ40032.1 - 0.0028 17.7 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain NmrA PF05368.8 KEZ40033.1 - 8e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ40033.1 - 2.7e-09 37.2 0.0 5.3e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1426 PF07234.6 KEZ40034.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) AMP-binding PF00501.23 KEZ40035.1 - 1.2e-249 827.7 0.0 2.3e-88 296.4 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KEZ40035.1 - 4.3e-173 574.1 0.0 1.8e-33 115.6 0.0 6.3 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 KEZ40035.1 - 1.1e-50 169.8 15.2 3.6e-08 33.5 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEZ40035.1 - 4.2e-16 59.6 0.0 2.8e-05 24.9 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 KEZ40035.1 - 2.7e-05 23.8 1.7 0.15 11.5 0.1 4.8 5 0 0 5 5 5 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.10 KEZ40035.1 - 4e-05 22.2 0.3 1.1 7.5 0.0 4.2 4 0 0 4 4 4 2 Transferase family DUF4406 PF14359.1 KEZ40035.1 - 0.11 12.5 0.0 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4406) NifZ PF04319.8 KEZ40035.1 - 0.41 10.0 0.1 1.1 8.6 0.1 1.6 1 0 0 1 1 1 0 NifZ domain AATase PF07247.7 KEZ40035.1 - 1 7.8 0.1 48 2.3 0.0 2.9 3 0 0 3 3 3 0 Alcohol acetyltransferase K_oxygenase PF13434.1 KEZ40036.1 - 1.9e-105 352.5 0.0 2.3e-105 352.3 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KEZ40036.1 - 1.2e-10 41.7 0.0 2.8e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ40036.1 - 4.8e-08 32.9 0.0 1.2e-06 28.4 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEZ40036.1 - 4.1e-05 23.5 0.0 8.6e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2360 PF10152.4 KEZ40036.1 - 0.35 11.1 3.3 0.66 10.2 2.3 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Collagen PF01391.13 KEZ40036.1 - 1.1 8.8 8.2 0.051 13.1 1.7 1.6 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) IF-2B PF01008.12 KEZ40037.1 - 6.4e-16 58.1 0.0 1.4e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KEZ40037.1 - 8.1e-08 31.9 0.0 8e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 NUDIX domain FF PF01846.14 KEZ40038.1 - 1.4e-10 40.9 0.3 1.4e-10 40.9 0.2 3.0 3 0 0 3 3 3 1 FF domain WW PF00397.21 KEZ40038.1 - 4.3e-09 36.0 3.7 4.3e-09 36.0 2.6 2.6 2 0 0 2 2 2 1 WW domain Cytochrom_B561 PF03188.11 KEZ40038.1 - 0.0061 16.3 3.8 0.011 15.5 2.6 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KEZ40038.1 - 0.073 12.6 1.0 0.21 11.2 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Ank_2 PF12796.2 KEZ40039.1 - 1.7e-18 66.7 0.8 5.5e-09 36.2 0.3 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ40039.1 - 7.9e-14 50.6 0.6 0.00018 21.1 0.1 4.6 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KEZ40039.1 - 5.1e-12 45.6 1.1 0.00035 20.7 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40039.1 - 3.2e-10 39.2 0.4 0.19 12.0 0.0 5.0 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEZ40039.1 - 4.2e-10 39.8 0.1 0.00051 20.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NTPase_I-T PF01931.13 KEZ40039.1 - 0.00061 19.5 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF84 Ank_2 PF12796.2 KEZ40040.1 - 6e-40 135.4 0.0 1.3e-10 41.4 0.0 4.8 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ40040.1 - 1.4e-25 87.7 0.0 0.0024 17.5 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 KEZ40040.1 - 9.4e-22 76.9 0.0 8.6e-06 26.1 0.0 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ40040.1 - 2.9e-19 68.6 0.1 2e-06 27.8 0.0 6.5 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40040.1 - 1.4e-18 65.1 0.0 0.005 16.9 0.0 8.4 8 0 0 8 8 8 4 Ankyrin repeat PNP_UDP_1 PF01048.15 KEZ40040.1 - 4.4e-09 35.6 0.1 2e-08 33.5 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 KEZ40040.1 - 1.7e-05 24.5 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ40040.1 - 3.7e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ40040.1 - 0.0032 17.6 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF3753 PF12575.3 KEZ40041.1 - 0.073 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Sec8_exocyst PF04048.9 KEZ40041.1 - 0.77 9.3 12.1 0.2 11.2 0.7 3.0 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain AAA_23 PF13476.1 KEZ40041.1 - 1.7 8.8 18.8 0.11 12.8 3.1 2.3 2 0 0 2 2 2 0 AAA domain Cluap1 PF10234.4 KEZ40041.1 - 8.4 5.5 22.4 8.4 5.5 4.3 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 PAP2 PF01569.16 KEZ40042.1 - 1.8e-23 82.6 2.0 1.8e-23 82.6 1.4 1.9 2 0 0 2 2 2 1 PAP2 superfamily Proteasome PF00227.21 KEZ40043.1 - 9.7e-61 204.3 0.1 1.2e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEZ40043.1 - 2.4e-14 52.3 0.2 6.9e-14 50.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KEZ40043.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.8 KEZ40044.1 - 5.1e-18 65.6 0.0 1.1e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 KEZ40044.1 - 6.9e-16 58.3 1.0 1.5e-15 57.2 0.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KEZ40044.1 - 3.5e-09 36.2 7.9 6.7e-09 35.3 5.5 1.5 1 0 0 1 1 1 1 PHD-finger Med7 PF05983.6 KEZ40045.1 - 1e-52 178.2 0.2 1.2e-52 177.9 0.1 1.1 1 0 0 1 1 1 1 MED7 protein Lsr2 PF11774.3 KEZ40046.1 - 0.011 15.6 1.5 0.013 15.4 1.1 1.1 1 0 0 1 1 1 0 Lsr2 CHASE3 PF05227.8 KEZ40046.1 - 0.05 13.2 0.6 0.059 13.0 0.4 1.1 1 0 0 1 1 1 0 CHASE3 domain Zn_ribbon_2 PF12674.2 KEZ40046.1 - 0.093 13.0 0.9 0.14 12.5 0.7 1.4 1 1 0 1 1 1 0 Putative zinc ribbon domain DUF406 PF04175.7 KEZ40046.1 - 0.13 12.7 0.7 0.39 11.2 0.1 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF406) DUF747 PF05346.6 KEZ40047.1 - 1.7e-102 342.9 0.2 2.3e-102 342.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family LAMTOR PF15454.1 KEZ40047.1 - 9.3e-11 41.8 0.1 2.9e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator HemY_N PF07219.8 KEZ40047.1 - 0.22 11.0 0.8 0.56 9.7 0.5 1.6 1 0 0 1 1 1 0 HemY protein N-terminus EBP PF05241.7 KEZ40048.1 - 3.4e-58 195.8 6.0 4.2e-58 195.5 4.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein Acyl_transf_1 PF00698.16 KEZ40049.1 - 6.5e-63 212.9 0.2 1.1e-62 212.2 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 KEZ40049.1 - 3.6e-61 206.8 0.5 3.2e-59 200.4 0.1 3.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KEZ40049.1 - 3e-59 200.6 2.3 6.1e-59 199.5 0.4 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 KEZ40049.1 - 2.5e-56 190.2 0.8 1.4e-55 187.7 0.1 2.8 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KEZ40049.1 - 4.1e-40 137.4 3.9 6.1e-40 136.8 0.1 3.4 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEZ40049.1 - 1.7e-33 114.9 0.1 4.8e-33 113.5 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEZ40049.1 - 9e-21 73.7 0.0 2.5e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KEZ40049.1 - 5.4e-19 68.5 0.0 1.6e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KEZ40049.1 - 1.7e-13 51.5 0.0 7.7e-12 46.2 0.0 3.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEZ40049.1 - 2.5e-13 50.0 0.0 1.1e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40049.1 - 6.8e-10 39.5 0.0 1e-08 35.7 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40049.1 - 1.2e-09 37.9 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40049.1 - 1.4e-07 31.9 0.0 4.6e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KEZ40049.1 - 1.6e-05 24.6 0.0 4.8e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEZ40049.1 - 0.00042 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 KEZ40049.1 - 0.008 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.6 KEZ40049.1 - 0.01 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.1 KEZ40049.1 - 0.066 14.0 0.0 0.37 11.6 0.0 2.4 2 0 0 2 2 1 0 Methyltransferase domain PCMT PF01135.14 KEZ40049.1 - 0.085 12.3 0.1 4.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.12 KEZ40049.1 - 0.22 10.8 0.0 0.53 9.6 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 KEZ40049.1 - 0.6 8.9 0.0 1.2 7.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Aminotran_1_2 PF00155.16 KEZ40050.1 - 5.7e-32 111.0 0.0 8.6e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ40050.1 - 0.00068 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KEZ40050.1 - 0.0018 16.6 0.0 0.0029 15.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEZ40050.1 - 0.026 13.5 0.2 0.082 11.9 0.0 1.9 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 KEZ40050.1 - 0.046 12.2 0.0 0.84 8.1 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.16 KEZ40050.1 - 0.057 12.2 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DLH PF01738.13 KEZ40051.1 - 1e-27 96.8 0.0 1.2e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ40051.1 - 5e-08 32.8 0.0 6.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ40051.1 - 0.0019 18.1 0.1 0.46 10.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 KEZ40051.1 - 0.02 13.9 0.0 0.063 12.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 KEZ40051.1 - 0.065 12.7 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ40051.1 - 0.07 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family BsuPI PF12690.2 KEZ40051.1 - 0.097 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Intracellular proteinase inhibitor WD40 PF00400.27 KEZ40052.1 - 4.4e-55 181.7 12.6 3e-09 36.3 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KEZ40052.1 - 3.3e-11 42.7 0.3 7.2e-11 41.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ40052.1 - 4.3e-11 42.1 0.5 1.4e-10 40.5 0.2 2.0 1 1 1 2 2 2 1 F-box domain PQQ_2 PF13360.1 KEZ40052.1 - 0.0029 17.0 0.9 0.15 11.4 0.6 2.8 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KEZ40052.1 - 0.004 15.3 6.7 5.4 5.0 0.7 5.0 3 2 0 3 3 3 2 Nucleoporin Nup120/160 FAM176 PF14851.1 KEZ40052.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 FAM176 family PRANC PF09372.5 KEZ40052.1 - 0.035 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 PRANC domain PQQ_3 PF13570.1 KEZ40052.1 - 0.11 12.7 1.5 39 4.7 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain UMPH-1 PF05822.7 KEZ40052.1 - 0.27 10.4 0.0 0.45 9.7 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) TraQ PF09679.5 KEZ40053.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) TPR_MLP1_2 PF07926.7 KEZ40054.1 - 1.9e-32 111.7 25.0 1.9e-32 111.7 17.3 18.0 10 5 4 16 16 16 5 TPR/MLP1/MLP2-like protein HOOK PF05622.7 KEZ40054.1 - 2e-05 22.6 13.9 2e-05 22.6 9.6 11.8 4 3 4 10 10 10 2 HOOK protein GAS PF13851.1 KEZ40054.1 - 0.00085 18.5 13.0 0.00085 18.5 9.0 15.9 7 5 7 16 16 16 5 Growth-arrest specific micro-tubule binding IncA PF04156.9 KEZ40054.1 - 0.002 17.7 19.1 0.002 17.7 13.3 17.4 6 4 9 15 15 15 1 IncA protein TMF_TATA_bd PF12325.3 KEZ40054.1 - 0.0027 17.4 14.8 0.0027 17.4 10.3 21.0 7 4 12 21 21 21 5 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 KEZ40054.1 - 0.0028 17.9 5.4 0.0028 17.9 3.7 22.9 13 7 5 18 18 18 3 Protein of unknown function (DUF904) SKG6 PF08693.5 KEZ40055.1 - 0.096 12.0 0.3 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mtc PF03820.12 KEZ40055.1 - 0.29 9.7 1.9 0.89 8.1 0.4 1.9 2 0 0 2 2 2 0 Tricarboxylate carrier PIR PF00399.14 KEZ40056.1 - 0.0005 19.3 2.6 0.0013 17.9 1.8 1.8 1 0 0 1 1 1 1 Yeast PIR protein repeat Glyco_hydro_2_C PF02836.12 KEZ40057.1 - 7.1e-101 337.0 0.1 1e-100 336.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KEZ40057.1 - 2.3e-52 177.7 0.0 3.6e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KEZ40057.1 - 6.8e-52 175.3 0.0 1.1e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KEZ40057.1 - 1.6e-12 47.8 0.1 4.6e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KEZ40057.1 - 0.032 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain DUF633 PF04816.7 KEZ40059.1 - 0.041 13.2 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF633) DUF982 PF06169.7 KEZ40059.1 - 0.081 12.6 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF982) DUF2456 PF10445.4 KEZ40061.1 - 5.1e-17 61.5 0.5 5.1e-17 61.5 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) DUF2730 PF10805.3 KEZ40062.1 - 0.003 17.2 1.8 0.0067 16.1 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) DUF3086 PF11285.3 KEZ40062.1 - 0.0079 15.0 0.3 0.0079 15.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3086) DivIC PF04977.10 KEZ40062.1 - 0.23 10.9 6.4 0.095 12.1 0.7 2.7 2 0 0 2 2 2 0 Septum formation initiator TBPIP PF07106.8 KEZ40062.1 - 0.81 9.2 5.9 1.4 8.4 0.5 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4164 PF13747.1 KEZ40062.1 - 1.3 9.2 10.4 1.8 8.7 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) CtIP_N PF10482.4 KEZ40062.1 - 3.9 7.2 13.0 4.6 7.0 1.7 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF4391 PF14335.1 KEZ40062.1 - 5.8 6.2 8.9 0.47 9.8 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) GMC_oxred_N PF00732.14 KEZ40063.1 - 1.3e-26 93.4 0.0 2.9e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ40063.1 - 9.6e-24 84.3 0.3 1.7e-23 83.4 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 KEZ40063.1 - 1.8e-11 43.5 8.0 6.4e-11 41.7 5.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 KEZ40063.1 - 1.5e-08 33.9 0.1 9.9e-05 21.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ40063.1 - 7.2e-07 28.4 0.1 0.00015 20.8 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ40063.1 - 1.1e-05 25.3 0.0 3.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEZ40063.1 - 3.2e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ40063.1 - 0.0011 18.1 0.1 0.0037 16.3 0.1 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEZ40063.1 - 0.0012 17.3 0.0 0.002 16.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KEZ40063.1 - 0.016 15.5 0.0 0.083 13.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ40063.1 - 0.016 14.2 0.1 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KEZ40063.1 - 0.017 14.1 0.0 0.076 12.0 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ40063.1 - 0.026 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KEZ40063.1 - 0.027 14.5 0.1 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.24 KEZ40064.1 - 4e-41 140.3 0.1 1.2e-40 138.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ40064.1 - 3.7e-21 74.7 0.0 7.6e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEZ40064.1 - 1.2e-06 27.5 0.0 2.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 KEZ40064.1 - 0.0052 15.2 0.0 0.98 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) Hira PF07569.6 KEZ40065.1 - 1.2e-83 279.6 0.0 3.7e-83 278.0 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KEZ40065.1 - 5.6e-43 143.3 19.3 2.6e-07 30.2 0.6 8.9 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 KEZ40065.1 - 4.5e-09 35.6 0.6 1.1e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 HIRA B motif Atrophin-1 PF03154.10 KEZ40065.1 - 7.8e-05 21.0 1.9 0.00013 20.2 1.3 1.2 1 0 0 1 1 1 1 Atrophin-1 family PD40 PF07676.7 KEZ40065.1 - 0.00049 19.7 1.4 36 4.1 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KEZ40065.1 - 0.0018 18.0 0.1 0.56 9.8 0.0 3.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KEZ40065.1 - 0.03 12.1 0.2 0.15 9.8 0.0 2.1 3 0 0 3 3 3 0 IKI3 family Glyco_transf_15 PF01793.11 KEZ40066.1 - 5.2e-18 65.0 2.4 1.5e-15 56.9 1.1 3.0 2 1 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase YhjQ PF06564.7 KEZ40066.1 - 0.097 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 YhjQ protein Nuc_sug_transp PF04142.10 KEZ40067.1 - 1.1e-72 244.0 2.0 1.6e-72 243.5 1.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KEZ40067.1 - 1.1e-08 34.3 7.4 4.8e-08 32.2 4.9 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KEZ40067.1 - 9.6e-06 25.3 17.8 0.0015 18.2 0.8 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KEZ40067.1 - 6.2e-05 23.1 17.7 0.001 19.2 1.4 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 KEZ40067.1 - 6.9e-05 22.8 23.9 0.0065 16.5 4.4 2.7 2 0 0 2 2 2 2 EamA-like transporter family NTP_transferase PF00483.18 KEZ40068.1 - 2.1e-29 102.5 0.0 3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 KEZ40068.1 - 7.8e-13 47.3 5.7 3.1e-06 26.4 0.0 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KEZ40068.1 - 2.3e-07 31.0 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF459 PF04311.8 KEZ40068.1 - 0.03 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Hexapep_2 PF14602.1 KEZ40068.1 - 0.11 12.1 0.6 3.8 7.1 0.0 3.1 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Dynamin_N PF00350.18 KEZ40069.1 - 1.2e-19 70.7 0.0 1.6e-18 67.0 0.0 2.6 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEZ40069.1 - 2.8e-15 55.9 0.1 4.8e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KEZ40069.1 - 2.1e-06 27.5 2.8 0.0002 21.1 0.0 2.8 3 0 0 3 3 3 2 Dynamin GTPase effector domain ABC_tran PF00005.22 KEZ40069.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sugar_tr PF00083.19 KEZ40070.1 - 1.9e-81 273.9 19.9 2.2e-81 273.7 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ40070.1 - 1.3e-27 96.4 16.3 1.7e-27 96.0 11.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ40070.1 - 2.3e-05 22.7 2.2 2.3e-05 22.7 1.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CBM_1 PF00734.13 KEZ40071.1 - 5.1e-15 54.8 9.6 1.4e-14 53.4 6.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 KEZ40071.1 - 2.8e-12 44.4 23.0 1.2 9.2 0.0 9.5 9 0 0 9 9 9 5 BNR/Asp-box repeat Kelch_6 PF13964.1 KEZ40071.1 - 0.006 16.7 0.6 15 5.9 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KEZ40071.1 - 1.2 9.4 15.0 2.9 8.1 0.1 5.6 5 0 0 5 5 5 0 Galactose oxidase, central domain Gpi16 PF04113.9 KEZ40072.1 - 2.3e-235 781.9 0.0 2.7e-235 781.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 KEZ40073.1 - 2e-71 240.5 2.7 2.5e-71 240.1 1.9 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF1241 PF06840.6 KEZ40073.1 - 0.005 16.1 0.4 0.051 12.8 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1241) AAA_13 PF13166.1 KEZ40073.1 - 0.0068 14.9 2.1 0.0094 14.4 1.5 1.2 1 0 0 1 1 1 1 AAA domain MCPsignal PF00015.16 KEZ40073.1 - 0.049 13.1 0.1 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FliJ PF02050.11 KEZ40073.1 - 0.051 13.6 3.3 0.11 12.5 0.4 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein DASH_Duo1 PF08651.5 KEZ40073.1 - 0.066 12.8 0.1 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 DASH complex subunit Duo1 Syntaxin PF00804.20 KEZ40073.1 - 0.099 12.8 0.3 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Syntaxin DUF4200 PF13863.1 KEZ40073.1 - 4.6 7.2 8.5 3 7.8 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Glyco_hydro_3 PF00933.16 KEZ40074.1 - 3.8e-53 180.4 0.0 5.3e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ40074.1 - 0.00087 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 KEZ40074.1 - 0.0011 18.9 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ40074.1 - 0.0039 17.3 0.0 0.012 15.7 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fe_hyd_SSU PF02256.12 KEZ40074.1 - 0.025 14.5 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit Acetyltransf_6 PF13480.1 KEZ40074.1 - 0.07 13.0 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 KEZ40075.1 - 1.2e-11 45.1 0.0 1.2e-10 41.8 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEZ40075.1 - 5.1e-09 36.2 0.0 9.6e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KEZ40075.1 - 1.5e-06 27.7 0.0 2.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEZ40075.1 - 3.9e-05 23.3 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase NDT80_PhoG PF05224.7 KEZ40076.1 - 4e-32 111.7 0.0 9.2e-32 110.5 0.0 1.6 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.15 KEZ40077.1 - 8.7e-23 81.0 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_1 PF00349.16 KEZ40078.1 - 9.8e-30 103.4 0.0 1.5e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KEZ40078.1 - 8e-29 100.5 0.0 2e-21 76.2 0.0 2.2 1 1 1 2 2 2 2 Hexokinase p450 PF00067.17 KEZ40079.1 - 5e-61 206.6 0.0 7.4e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3584 PF12128.3 KEZ40080.1 - 0.00037 18.0 47.0 0.00037 18.0 32.6 4.3 1 1 3 4 4 4 3 Protein of unknown function (DUF3584) Filament PF00038.16 KEZ40080.1 - 0.00092 18.7 151.9 0.31 10.4 32.3 7.0 1 1 1 4 4 4 3 Intermediate filament protein Mannosyl_trans2 PF04188.8 KEZ40081.1 - 6.9e-62 209.8 7.1 9.3e-62 209.3 4.9 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) PMT_2 PF13231.1 KEZ40081.1 - 1.4e-05 25.0 19.9 1.7e-05 24.7 5.7 2.9 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PTPA PF03095.10 KEZ40082.1 - 7.2e-108 360.2 0.0 8.3e-108 360.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Patched PF02460.13 KEZ40084.1 - 6.1e-74 249.3 14.0 3.7e-48 164.1 1.2 2.0 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KEZ40084.1 - 3e-51 172.8 6.5 3e-51 172.8 4.5 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KEZ40084.1 - 6.7e-07 28.3 31.9 0.0001 21.1 7.3 2.6 3 0 0 3 3 3 2 MMPL family ACR_tran PF00873.14 KEZ40084.1 - 0.23 8.8 18.0 0.011 13.1 7.3 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Amidase PF01425.16 KEZ40085.1 - 1.2e-73 248.4 0.0 1.6e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Amidase TauD PF02668.11 KEZ40086.1 - 5.4e-45 154.0 0.4 6.3e-45 153.8 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KEZ40086.1 - 0.0043 17.5 0.1 0.95 10.0 0.0 2.6 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily TcpQ PF10671.4 KEZ40086.1 - 0.12 12.2 0.2 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Endonuc-FokI_C PF09254.6 KEZ40086.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Pribosyltran PF00156.22 KEZ40087.1 - 9.1e-09 35.1 0.4 8e-08 32.0 0.3 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.1 KEZ40088.1 - 1.3e-40 137.7 0.0 3.3e-40 136.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KEZ40088.1 - 3.6e-38 131.1 1.3 5.5e-32 111.0 0.4 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KEZ40088.1 - 1.4e-12 47.4 0.6 2.9e-12 46.3 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEZ40088.1 - 0.052 12.7 0.2 0.12 11.5 0.1 1.6 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase DPM3 PF08285.6 KEZ40091.1 - 2.8e-34 116.8 0.1 3.1e-34 116.6 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Zn_clus PF00172.13 KEZ40092.1 - 3.9e-08 33.0 6.3 3.9e-08 33.0 4.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KEZ40093.1 - 7.5e-16 58.5 0.0 1.7e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ40093.1 - 0.002 18.2 0.4 0.021 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ40093.1 - 0.0023 17.6 0.0 0.0071 16.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KEZ40093.1 - 0.006 16.5 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEZ40093.1 - 0.011 16.4 2.2 0.028 15.2 0.0 3.0 3 1 1 4 4 4 0 AAA domain AAA_5 PF07728.9 KEZ40093.1 - 0.029 14.1 0.0 0.084 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 KEZ40093.1 - 0.029 13.9 0.7 2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEZ40093.1 - 0.063 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KEZ40093.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Torsin ATP-synt_ab PF00006.20 KEZ40093.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain p450 PF00067.17 KEZ40095.1 - 5.3e-63 213.1 0.0 6.6e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LRR_4 PF12799.2 KEZ40096.1 - 1.1e-40 136.5 22.1 1e-07 31.3 0.5 10.0 8 2 1 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ40096.1 - 1.8e-35 120.4 24.0 2.8e-08 33.3 0.5 6.9 4 1 2 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KEZ40096.1 - 4.8e-16 56.3 30.3 0.37 11.0 0.0 15.0 16 2 2 18 18 18 5 Leucine Rich Repeat LRR_7 PF13504.1 KEZ40096.1 - 1.2e-10 39.8 21.8 0.74 10.2 0.1 12.9 14 0 0 14 14 14 2 Leucine rich repeat LRR_6 PF13516.1 KEZ40096.1 - 4.6e-06 26.1 17.8 0.83 9.9 0.0 8.8 8 1 1 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.1 KEZ40096.1 - 0.025 14.1 7.6 0.53 9.8 0.0 4.6 2 2 4 6 6 6 0 Leucine-rich repeat zf-CCCH PF00642.19 KEZ40097.1 - 2.1e-08 33.6 3.4 4.1e-08 32.7 2.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 KEZ40097.1 - 2.5e-08 33.7 9.8 4.3e-08 33.0 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ40097.1 - 3.5e-08 32.9 4.3 6e-08 32.2 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ40097.1 - 3.5e-07 29.9 7.2 5.6e-07 29.2 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEZ40097.1 - 1.7e-06 27.5 9.0 3e-06 26.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ40097.1 - 2.3e-06 27.2 8.2 3.9e-06 26.4 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEZ40097.1 - 3.4e-05 23.4 3.5 7e-05 22.4 2.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KEZ40097.1 - 0.0052 16.6 8.5 0.011 15.6 5.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KEZ40097.1 - 0.056 12.9 1.2 0.1 12.1 0.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 KEZ40097.1 - 0.24 11.5 4.9 0.67 10.1 3.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 KEZ40097.1 - 2 7.9 7.1 4.1 7.0 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cript PF10235.4 KEZ40097.1 - 3.7 7.9 7.2 0.31 11.4 1.0 2.2 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT Sec15 PF04091.7 KEZ40098.1 - 3.1e-84 282.9 5.0 3.1e-84 282.9 3.5 2.4 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like FAD_binding_4 PF01565.18 KEZ40098.1 - 1.6e-28 98.8 0.0 2.9e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF4201 PF13870.1 KEZ40098.1 - 0.26 10.7 13.3 0.086 12.2 2.3 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) TrkH PF02386.11 KEZ40099.1 - 1.3e-101 339.6 14.2 2.6e-100 335.4 6.4 2.1 2 0 0 2 2 2 2 Cation transport protein NmrA PF05368.8 KEZ40100.1 - 1.7e-15 56.9 0.1 5.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family Semialdhyde_dh PF01118.19 KEZ40100.1 - 0.0019 18.4 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KEZ40100.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 KEZ40100.1 - 0.15 12.0 0.9 0.71 9.8 0.6 2.0 1 1 0 1 1 1 0 NADH(P)-binding DUF4448 PF14610.1 KEZ40101.1 - 5e-27 94.6 0.0 6.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KEZ40101.1 - 0.0026 17.0 2.0 0.0079 15.4 1.4 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain FTSW_RODA_SPOVE PF01098.14 KEZ40101.1 - 0.043 12.5 0.0 0.063 12.0 0.0 1.1 1 0 0 1 1 1 0 Cell cycle protein TctB PF07331.6 KEZ40101.1 - 0.048 13.3 0.5 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family GSDH PF07995.6 KEZ40102.1 - 2.1e-06 27.0 0.0 4.3e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 KEZ40102.1 - 6.8e-05 22.3 0.0 0.015 14.6 0.0 2.8 3 0 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KEZ40102.1 - 0.0073 16.2 0.0 0.52 10.3 0.0 3.8 3 1 1 4 4 4 1 NHL repeat Reg_prop PF07494.6 KEZ40102.1 - 0.074 13.1 0.0 0.79 9.9 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller AMP-binding PF00501.23 KEZ40103.1 - 5.7e-71 239.0 0.0 8e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KEZ40103.1 - 1e-62 211.3 0.0 1.6e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KEZ40103.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KEZ40103.1 - 2.1e-09 37.5 0.0 6.1e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEZ40103.1 - 9.5e-09 36.0 0.0 3.8e-08 34.1 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 KEZ40103.1 - 0.00071 19.6 0.0 0.017 15.1 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ40103.1 - 0.0012 17.6 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HEAT_2 PF13646.1 KEZ40104.1 - 2.6e-06 27.5 6.5 0.0026 17.9 0.0 4.0 3 1 1 4 4 4 2 HEAT repeats Arm PF00514.18 KEZ40104.1 - 0.00054 19.6 7.1 0.005 16.6 0.2 4.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KEZ40104.1 - 0.0028 17.5 0.1 0.016 15.2 0.1 2.4 1 0 0 1 1 1 1 HEAT repeat Arm_2 PF04826.8 KEZ40104.1 - 0.02 13.9 0.1 4.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Armadillo-like KAP PF05804.7 KEZ40104.1 - 0.043 11.7 0.0 0.31 8.9 0.0 1.9 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) Mur_ligase_C PF02875.16 KEZ40104.1 - 0.085 12.9 0.0 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Adaptin_N PF01602.15 KEZ40104.1 - 0.11 10.8 0.8 0.92 7.7 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Proteasom_PSMB PF10508.4 KEZ40104.1 - 0.14 10.3 0.0 0.32 9.1 0.0 1.6 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 KEZ40104.1 - 0.77 10.3 5.4 1.5 9.4 0.1 4.2 4 1 0 4 4 4 0 HEAT-like repeat Ribosomal_L13e PF01294.13 KEZ40105.1 - 1.7e-60 203.5 2.2 2.1e-60 203.2 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e COX14 PF14880.1 KEZ40106.1 - 1.3e-16 59.9 0.4 2.1e-16 59.2 0.3 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Myb_DNA-bind_4 PF13837.1 KEZ40106.1 - 0.0025 17.8 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PilJ PF13675.1 KEZ40106.1 - 0.057 13.7 3.9 0.089 13.1 2.2 1.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CD52 PF15116.1 KEZ40106.1 - 1.2 9.0 5.0 1.6 8.5 2.7 1.9 1 1 1 2 2 2 0 CAMPATH-1 antigen DAHP_synth_1 PF00793.15 KEZ40108.1 - 9.7e-102 339.2 0.2 1.2e-101 339.0 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_L50 PF10501.4 KEZ40110.1 - 2.9e-16 59.4 0.1 2.6e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 Ribosomal subunit 39S CVNH PF08881.5 KEZ40111.1 - 3.6e-30 104.2 0.2 3.9e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 CVNH domain ABC2_membrane PF01061.19 KEZ40112.1 - 8.7e-101 335.4 56.4 7.5e-51 172.2 13.8 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KEZ40112.1 - 2.8e-38 129.7 6.0 1.3e-32 111.5 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 KEZ40112.1 - 3.4e-35 121.3 0.0 1.3e-16 61.1 0.0 3.2 3 1 1 4 4 4 2 ABC transporter ABC_trans_N PF14510.1 KEZ40112.1 - 4.8e-21 74.6 0.0 1.1e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KEZ40112.1 - 9.7e-08 32.2 1.2 1.8e-05 24.7 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KEZ40112.1 - 1.6e-07 30.9 0.2 0.00016 21.1 0.1 2.7 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEZ40112.1 - 3.1e-06 26.4 0.1 0.00087 18.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KEZ40112.1 - 3e-05 23.2 10.7 3e-05 23.2 7.4 4.1 3 2 0 3 3 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 KEZ40112.1 - 3.5e-05 23.2 0.7 0.023 14.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 KEZ40112.1 - 0.00027 20.8 0.1 0.053 13.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEZ40112.1 - 0.00079 18.9 1.1 0.062 12.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KEZ40112.1 - 0.0014 18.7 0.1 0.97 9.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 KEZ40112.1 - 0.0018 18.2 0.1 0.8 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KEZ40112.1 - 0.0029 17.2 0.9 3 7.6 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 KEZ40112.1 - 0.0079 16.5 0.0 0.85 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ40112.1 - 0.0085 16.9 0.0 2.8 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KEZ40112.1 - 0.016 14.4 0.0 4.9 6.3 0.0 3.7 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KEZ40112.1 - 0.017 14.7 0.6 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KEZ40112.1 - 0.091 12.7 0.7 2.7 7.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 KEZ40112.1 - 0.1 12.7 0.0 22 5.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KEZ40112.1 - 0.11 12.1 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KEZ40112.1 - 0.12 11.9 1.3 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEZ40112.1 - 0.16 11.4 0.1 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KEZ40112.1 - 0.18 11.2 0.1 26 4.1 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.1 KEZ40112.1 - 0.18 12.0 0.1 0.5 10.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 KEZ40112.1 - 0.26 11.2 0.0 35 4.4 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KEZ40112.1 - 0.57 9.5 2.5 10 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain PDR_assoc PF08370.6 KEZ40112.1 - 9.2 5.8 9.7 0.73 9.3 0.1 3.7 4 0 0 4 4 4 0 Plant PDR ABC transporter associated Vint PF14623.1 KEZ40113.1 - 6.5e-47 159.0 0.0 1.1e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KEZ40113.1 - 6e-22 77.5 0.0 1.1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 KEZ40113.1 - 8.8e-17 61.7 0.0 2.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEZ40113.1 - 3.1e-15 56.3 0.0 5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KEZ40113.1 - 1.6e-10 40.8 0.1 1.9e-08 34.1 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain Hint_2 PF13403.1 KEZ40113.1 - 0.046 13.6 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Hint domain Hint PF01079.15 KEZ40113.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Hint module RCC1 PF00415.13 KEZ40114.1 - 3.2e-60 200.1 0.4 7.6e-08 32.4 0.0 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEZ40114.1 - 2.2e-41 138.6 24.4 5.2e-09 35.4 0.3 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KEZ40114.1 - 0.00046 19.6 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 Putative carbohydrate binding domain TPR_7 PF13176.1 KEZ40115.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Sec34 PF04136.10 KEZ40116.1 - 1.5e-25 89.7 1.0 1.5e-25 89.7 0.7 2.2 3 0 0 3 3 3 1 Sec34-like family NAD_binding_10 PF13460.1 KEZ40117.1 - 6.5e-21 75.1 0.0 5.7e-20 72.0 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KEZ40117.1 - 4.3e-07 29.4 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.16 KEZ40117.1 - 0.00074 19.0 0.0 0.034 13.5 0.0 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KEZ40117.1 - 0.018 14.2 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KEZ40117.1 - 0.07 12.5 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KEZ40117.1 - 0.075 13.4 0.2 0.5 10.8 0.0 2.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 KEZ40117.1 - 0.083 12.5 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 KR domain zf-C3HC PF07967.8 KEZ40118.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like AMP-binding PF00501.23 KEZ40119.1 - 2.8e-89 299.3 0.0 3.3e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ40119.1 - 1.4e-10 41.9 0.0 3.3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2575 PF10837.3 KEZ40119.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) ECH PF00378.15 KEZ40120.1 - 1e-48 165.5 0.0 1.2e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Carboxyl_trans PF01039.17 KEZ40121.1 - 1e-101 340.7 0.0 7.1e-99 331.3 0.0 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain CN_hydrolase PF00795.17 KEZ40122.1 - 9e-34 116.4 0.0 1.2e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 KEZ40123.1 - 9.2e-30 103.3 0.0 1.7e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ40123.1 - 6.2e-23 81.0 40.8 6.2e-23 81.0 28.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40124.1 - 3.7e-84 282.8 23.6 4.3e-84 282.6 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ40124.1 - 6.9e-27 94.0 54.3 9e-22 77.2 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 KEZ40124.1 - 0.47 9.9 2.0 2.7 7.5 1.4 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Fungal_trans PF04082.13 KEZ40125.1 - 0.00018 20.4 0.1 0.032 13.1 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain p450 PF00067.17 KEZ40126.1 - 1.3e-40 139.3 0.0 1.6e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1386 PF07138.6 KEZ40126.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) MFS_1 PF07690.11 KEZ40127.1 - 5.3e-32 110.9 28.9 5.7e-31 107.4 20.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Gly_transf_sug PF04488.10 KEZ40127.1 - 2.7e-09 37.3 0.0 6.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KEZ40127.1 - 0.0042 15.6 0.0 0.11 10.9 0.1 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain NAD_binding_10 PF13460.1 KEZ40128.1 - 1.4e-20 74.1 0.0 2.6e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEZ40128.1 - 2.6e-10 39.9 0.0 1.8e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KEZ40128.1 - 5.2e-08 32.6 0.0 0.0056 16.1 0.0 4.0 3 1 1 4 4 4 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KEZ40128.1 - 0.05 13.5 0.5 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase PHO4 PF01384.15 KEZ40129.1 - 4.3e-100 334.5 13.7 5.1e-100 334.2 9.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family CMAS PF02353.15 KEZ40130.1 - 2.5e-61 207.1 0.1 3.1e-61 206.8 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KEZ40130.1 - 2.5e-11 43.5 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40130.1 - 0.00011 22.5 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ40130.1 - 0.00018 21.5 0.0 0.0021 18.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40130.1 - 0.00034 21.1 0.0 0.00097 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ40130.1 - 0.00095 18.5 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 KEZ40130.1 - 0.0055 16.0 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 KEZ40130.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KEZ40130.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ40130.1 - 0.021 15.1 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ40130.1 - 0.021 15.2 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.13 KEZ40130.1 - 0.067 12.6 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 DNA methylase Methyltransf_32 PF13679.1 KEZ40130.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KEZ40131.1 - 5.5e-09 36.1 0.0 8.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase FAD_binding_4 PF01565.18 KEZ40133.1 - 5.1e-20 71.3 0.0 1.4e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ40133.1 - 1.5e-10 40.8 0.1 2.7e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3429 PF11911.3 KEZ40134.1 - 0.17 11.8 7.9 0.29 11.1 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3429) VIT1 PF01988.14 KEZ40134.1 - 0.37 10.2 9.1 0.97 8.8 6.3 1.8 1 1 0 1 1 1 0 VIT family DUF3325 PF11804.3 KEZ40134.1 - 0.43 10.5 8.0 0.65 9.9 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) DUF3681 PF12442.3 KEZ40134.1 - 0.54 10.4 6.0 0.48 10.6 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) ABC_tran PF00005.22 KEZ40135.1 - 9.2e-38 129.6 0.0 2.3e-18 66.8 0.0 2.9 2 1 1 3 3 3 2 ABC transporter ABC_membrane PF00664.18 KEZ40135.1 - 2.4e-22 79.6 32.0 1.7e-17 63.7 7.1 2.4 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 KEZ40135.1 - 2.2e-09 37.7 0.2 0.0021 18.0 0.0 3.3 2 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KEZ40135.1 - 5.9e-08 32.2 0.2 0.038 13.2 0.0 3.3 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEZ40135.1 - 0.00019 20.8 0.0 0.00049 19.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KEZ40135.1 - 0.00047 20.0 0.1 1.3 8.9 0.0 2.9 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 KEZ40135.1 - 0.0037 17.1 0.1 0.0098 15.7 0.1 1.7 1 0 0 1 1 1 1 Dynamin family AAA_23 PF13476.1 KEZ40135.1 - 0.0079 16.5 0.1 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEZ40135.1 - 0.03 13.7 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEZ40135.1 - 0.044 13.9 0.2 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEZ40135.1 - 0.045 13.6 0.1 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEZ40135.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 KEZ40135.1 - 0.066 12.9 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 KEZ40135.1 - 0.13 11.7 0.2 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KEZ40135.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Beta-lactamase PF00144.19 KEZ40137.1 - 1e-46 159.4 0.2 1.3e-46 159.1 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Cyclase PF04199.8 KEZ40138.1 - 2.3e-13 50.1 0.1 3.4e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 KEZ40139.1 - 1.9e-79 267.3 16.1 2.2e-79 267.1 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ40139.1 - 3.7e-28 98.2 13.5 5.5e-28 97.6 9.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ40139.1 - 5.6e-06 24.8 0.4 5.6e-06 24.8 0.3 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KEZ40139.1 - 0.00011 20.7 2.9 0.00011 20.7 2.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Pkinase PF00069.20 KEZ40140.1 - 1.2e-15 57.4 0.0 2e-14 53.3 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEZ40140.1 - 0.011 15.4 0.2 0.035 13.8 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KEZ40140.1 - 0.036 13.1 0.0 3.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase Kdo PF06293.9 KEZ40140.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_114 PF03537.8 KEZ40141.1 - 6.2e-13 48.3 0.2 1.3e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ABC2_membrane PF01061.19 KEZ40142.1 - 1.3e-26 93.0 27.9 1.9e-26 92.5 19.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KEZ40142.1 - 3.2e-25 89.0 0.1 5.6e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEZ40142.1 - 2.2e-09 37.6 0.3 0.00039 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KEZ40142.1 - 8e-06 25.2 0.0 2.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KEZ40142.1 - 2.7e-05 23.4 0.0 0.039 13.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEZ40142.1 - 4e-05 23.1 0.1 7.6e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ40142.1 - 5.5e-05 23.2 0.1 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KEZ40142.1 - 0.0002 20.8 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KEZ40142.1 - 0.00025 21.8 0.1 0.0011 19.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 KEZ40142.1 - 0.00032 20.1 0.4 0.00065 19.1 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KEZ40142.1 - 0.00064 18.9 0.1 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ40142.1 - 0.00081 19.5 0.1 0.0021 18.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ40142.1 - 0.0009 18.9 0.1 0.0019 17.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 KEZ40142.1 - 0.0015 17.4 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 KEZ40142.1 - 0.0027 18.0 0.3 0.0099 16.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEZ40142.1 - 0.0032 16.8 0.1 0.0083 15.5 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KEZ40142.1 - 0.0034 17.2 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEZ40142.1 - 0.0037 17.2 0.1 0.0067 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KEZ40142.1 - 0.0039 17.1 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 KEZ40142.1 - 0.0042 16.6 0.5 0.0076 15.8 0.4 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KEZ40142.1 - 0.0051 16.5 0.2 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 NTPase NACHT PF05729.7 KEZ40142.1 - 0.0061 16.2 0.1 0.014 15.0 0.1 1.6 2 0 0 2 2 1 1 NACHT domain RuvB_N PF05496.7 KEZ40142.1 - 0.008 15.2 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 KEZ40142.1 - 0.012 15.0 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 KEZ40142.1 - 0.012 15.0 0.3 0.02 14.3 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEZ40142.1 - 0.016 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KEZ40142.1 - 0.016 15.5 0.3 0.032 14.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KEZ40142.1 - 0.031 13.8 0.2 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 KEZ40142.1 - 0.041 14.0 0.1 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEZ40142.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 KEZ40142.1 - 0.068 12.8 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 KEZ40142.1 - 0.09 12.6 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 KEZ40142.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 KEZ40142.1 - 0.14 11.9 0.0 0.66 9.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KEZ40142.1 - 0.16 11.3 1.0 0.27 10.6 0.3 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain CBM_5_12 PF02839.9 KEZ40143.1 - 7.7e-07 28.5 4.9 2.4e-06 27.0 3.4 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain PT-TG PF14449.1 KEZ40144.1 - 3.6e-05 23.4 0.3 0.00011 21.8 0.0 2.0 2 0 0 2 2 2 1 Pre-toxin TG Peptidase_M13_N PF05649.8 KEZ40145.1 - 5.2e-94 315.4 0.0 7.2e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KEZ40145.1 - 3.8e-57 192.8 0.1 8.6e-57 191.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_MA_2 PF13485.1 KEZ40145.1 - 0.026 14.5 0.1 0.055 13.5 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily MFS_1 PF07690.11 KEZ40146.1 - 1.8e-30 105.8 56.7 4.6e-25 88.0 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40146.1 - 1.5e-07 30.3 37.8 0.0019 16.8 9.2 3.7 1 1 2 3 3 3 3 Sugar (and other) transporter adh_short PF00106.20 KEZ40147.1 - 1e-24 87.3 0.1 1.6e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ40147.1 - 2.1e-17 63.7 0.1 2.6e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ40147.1 - 3.9e-10 39.6 0.1 8e-10 38.6 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KEZ40147.1 - 9.2e-09 35.5 0.1 1.6e-08 34.7 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KEZ40147.1 - 0.00083 18.3 0.0 0.0016 17.3 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KEZ40147.1 - 0.0023 17.4 0.1 0.0059 16.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KEZ40147.1 - 0.024 13.8 0.0 0.15 11.2 0.0 1.9 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KEZ40147.1 - 0.026 14.3 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 KEZ40148.1 - 4.4e-20 71.6 0.3 6.1e-20 71.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40148.1 - 1.9e-10 40.5 9.2 3.5e-10 39.6 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KEZ40149.1 - 3.8e-07 30.2 0.6 2.2e-06 27.7 0.1 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ40149.1 - 0.012 15.3 0.4 0.032 14.0 0.1 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family Beta-lactamase PF00144.19 KEZ40150.1 - 8.5e-42 143.3 0.8 3.8e-41 141.1 0.2 1.9 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 KEZ40150.1 - 5e-09 35.9 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Arf PF00025.16 KEZ40151.1 - 4.9e-27 94.2 0.0 8.4e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ40151.1 - 2.5e-06 26.8 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KEZ40151.1 - 3.4e-05 22.6 0.7 0.079 11.6 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.17 KEZ40151.1 - 8.1e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEZ40151.1 - 0.00079 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KEZ40151.1 - 0.0009 19.7 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEZ40151.1 - 0.039 13.3 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NAD_binding_10 PF13460.1 KEZ40152.1 - 2e-10 41.0 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEZ40152.1 - 0.00013 21.3 0.0 0.00026 20.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family TrkH PF02386.11 KEZ40153.1 - 4e-104 348.0 1.6 7e-100 334.0 0.6 2.0 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.11 KEZ40154.1 - 1.1e-33 114.7 22.6 1.4e-19 69.5 3.4 2.7 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 KEZ40154.1 - 0.0061 15.8 0.3 0.0061 15.8 0.2 3.2 2 1 1 3 3 3 1 Ion transport protein Aminotran_1_2 PF00155.16 KEZ40155.1 - 4.5e-34 117.9 0.0 5.7e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ40155.1 - 0.037 13.1 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Lactamase_B PF00753.22 KEZ40156.1 - 6.9e-23 81.3 3.1 9.2e-23 80.8 2.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEZ40156.1 - 0.00028 20.4 0.6 0.00037 20.1 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NB-ARC PF00931.17 KEZ40157.1 - 8.7e-08 31.3 0.0 1.6e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 NB-ARC domain Abhydrolase_5 PF12695.2 KEZ40157.1 - 1.3e-05 25.0 0.0 3.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ40157.1 - 0.00015 21.7 0.0 0.012 15.4 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KEZ40157.1 - 0.0012 18.8 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ40157.1 - 0.003 17.6 0.0 0.0082 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 KEZ40157.1 - 0.024 13.9 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) IstB_IS21 PF01695.12 KEZ40157.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein PGAP1 PF07819.8 KEZ40157.1 - 0.041 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MutS_III PF05192.13 KEZ40157.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 MutS domain III Peptidase_M15_2 PF05951.8 KEZ40158.1 - 0.0044 16.4 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) GFO_IDH_MocA PF01408.17 KEZ40159.1 - 1.7e-07 31.7 0.0 3.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ATP-grasp_4 PF13535.1 KEZ40160.1 - 4.8e-22 78.5 0.0 2.8e-20 72.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEZ40160.1 - 1.6e-06 27.6 0.0 4.3e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 KEZ40160.1 - 1.1e-05 24.4 0.0 0.037 12.7 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 KEZ40160.1 - 0.0012 18.7 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.11 KEZ40160.1 - 0.0049 16.0 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GARS_A PF01071.14 KEZ40160.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 KEZ40160.1 - 0.021 14.1 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ABC_membrane PF00664.18 KEZ40161.1 - 1.1e-78 264.4 32.1 3.7e-40 138.0 9.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ40161.1 - 1.2e-70 236.1 0.0 1.1e-34 119.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ40161.1 - 3.4e-16 59.1 0.2 1.6e-05 24.2 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ40161.1 - 3e-09 37.2 0.0 0.062 13.2 0.0 4.2 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KEZ40161.1 - 1.9e-08 33.6 0.5 0.0046 16.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 KEZ40161.1 - 1.2e-07 30.7 3.4 0.0022 16.6 0.1 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KEZ40161.1 - 3.8e-07 30.2 6.1 0.0036 17.2 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KEZ40161.1 - 5.3e-07 28.9 0.0 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ40161.1 - 5.3e-06 27.2 0.0 0.15 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEZ40161.1 - 5.3e-06 26.0 1.2 0.43 9.9 0.0 4.1 4 0 0 4 4 4 1 AAA-like domain AAA_22 PF13401.1 KEZ40161.1 - 7.9e-06 26.0 1.3 0.33 11.0 0.2 4.4 3 2 0 3 3 2 2 AAA domain AAA_30 PF13604.1 KEZ40161.1 - 1.5e-05 24.7 0.6 1.9 8.0 0.0 4.8 5 0 0 5 5 5 2 AAA domain DUF87 PF01935.12 KEZ40161.1 - 0.00014 21.8 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_5 PF07728.9 KEZ40161.1 - 0.00017 21.3 0.1 3.3 7.4 0.0 4.5 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEZ40161.1 - 0.00055 19.8 0.0 1 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEZ40161.1 - 0.0019 17.6 4.5 0.34 10.3 0.1 4.0 3 1 0 3 3 3 1 AAA domain Katanin_con80 PF13925.1 KEZ40161.1 - 0.004 16.8 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 1 con80 domain of Katanin MobB PF03205.9 KEZ40161.1 - 0.0057 16.3 0.0 4.5 6.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KEZ40161.1 - 0.0076 16.5 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 KEZ40161.1 - 0.014 14.1 0.0 0.54 8.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KEZ40161.1 - 0.026 14.5 0.1 13 5.8 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KEZ40161.1 - 0.032 13.3 0.5 5.5 6.0 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.1 KEZ40161.1 - 0.041 14.1 0.0 16 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KEZ40161.1 - 0.062 12.8 0.2 9.3 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KEZ40161.1 - 0.069 12.7 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.12 KEZ40161.1 - 0.09 12.2 0.0 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.1 KEZ40161.1 - 0.18 11.7 9.5 0.93 9.4 0.2 4.5 4 2 0 4 4 3 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KEZ40161.1 - 0.22 12.0 1.8 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein Aminotran_3 PF00202.16 KEZ40162.1 - 7.1e-85 284.8 0.1 8.4e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KEZ40162.1 - 2.7e-05 23.2 0.0 6.1e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II adh_short PF00106.20 KEZ40163.1 - 1.9e-09 37.6 0.6 3.7e-09 36.7 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEZ40163.1 - 0.00021 20.8 0.0 0.00035 20.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEZ40163.1 - 0.00022 21.0 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 KEZ40163.1 - 0.002 17.1 0.1 0.0078 15.1 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein p450 PF00067.17 KEZ40164.1 - 1.5e-61 208.3 0.0 1.9e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OsmC PF02566.14 KEZ40165.1 - 1.9e-17 63.2 0.0 4e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 OsmC-like protein NOA36 PF06524.7 KEZ40165.1 - 0.23 10.6 4.2 0.34 10.1 2.9 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KEZ40165.1 - 1.5 8.2 6.8 2.7 7.4 4.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Kelch_3 PF13415.1 KEZ40166.1 - 2.4e-31 107.1 6.3 3.1e-08 33.5 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KEZ40166.1 - 6.1e-27 93.1 13.7 1.4e-14 53.5 0.1 6.9 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEZ40166.1 - 1.3e-18 66.2 4.8 0.00016 21.6 0.1 6.4 4 1 2 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KEZ40166.1 - 4.4e-13 48.8 1.1 0.024 14.5 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KEZ40166.1 - 2.7e-11 42.8 5.2 0.0047 16.4 0.0 6.0 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.10 KEZ40166.1 - 6.2e-06 25.7 11.7 0.23 11.2 0.1 6.4 7 1 0 7 7 7 3 Kelch motif Abhydrolase_4 PF08386.5 KEZ40167.1 - 5.4e-24 84.0 0.0 9.2e-24 83.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEZ40167.1 - 5e-15 55.6 0.0 4e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ40167.1 - 1.1e-08 35.2 0.0 1.3e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ40167.1 - 0.048 13.4 0.0 0.7 9.6 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KEZ40168.1 - 8.6e-20 70.7 81.8 1.1e-14 53.9 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ40168.1 - 2.9e-06 25.9 13.2 2.9e-06 25.9 9.1 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 KEZ40169.1 - 3.1e-23 82.0 37.2 1.1e-11 44.0 4.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily FxsA PF04186.8 KEZ40169.1 - 0.0031 17.1 2.9 0.015 14.9 2.0 2.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein p450 PF00067.17 KEZ40170.1 - 4.7e-38 130.9 0.0 6.2e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KEZ40171.1 - 0 1338.1 4.0 8e-86 288.0 0.0 6.3 5 1 1 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 KEZ40171.1 - 1.1e-150 500.6 0.0 5.4e-37 127.2 0.0 7.0 5 2 0 5 5 5 5 Condensation domain PP-binding PF00550.20 KEZ40171.1 - 2.2e-62 207.2 3.0 3.9e-09 36.6 0.0 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEZ40171.1 - 5.2e-25 88.1 0.0 2.7e-06 28.2 0.0 5.8 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain RGS PF00615.14 KEZ40171.1 - 1.9 8.6 0.1 76 3.4 0.0 3.1 3 0 0 3 3 3 0 Regulator of G protein signaling domain CAT PF00302.13 KEZ40171.1 - 2.7 7.5 0.1 29 4.1 0.0 2.6 3 0 0 3 3 3 0 Chloramphenicol acetyltransferase DUF2052 PF09747.4 KEZ40171.1 - 5.6 6.8 0.1 12 5.7 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AATase PF07247.7 KEZ40171.1 - 9.6 4.6 0.0 32 2.9 0.0 1.7 2 0 0 2 2 2 0 Alcohol acetyltransferase Sugar_tr PF00083.19 KEZ40172.1 - 2.4e-54 184.6 24.2 3.2e-54 184.2 16.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 KEZ40172.1 - 9.3e-22 78.0 0.0 9.3e-22 78.0 0.0 2.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family MFS_1 PF07690.11 KEZ40172.1 - 1.8e-21 76.2 65.2 3.5e-20 72.0 26.9 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Abhydrolase_5 PF12695.2 KEZ40172.1 - 0.0001 22.1 0.2 0.00027 20.7 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ40172.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF4387 PF14330.1 KEZ40173.1 - 6.6e-31 106.5 0.0 1.3e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 KEZ40173.1 - 3.5e-09 35.6 0.0 2.5e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Fungal_trans PF04082.13 KEZ40174.1 - 5.2e-13 48.4 0.2 8.5e-13 47.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Matrilin_ccoil PF10393.4 KEZ40174.1 - 0.054 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Reprolysin_5 PF13688.1 KEZ40175.1 - 2.1e-14 53.9 0.1 3.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KEZ40175.1 - 4.7e-09 36.0 0.0 5.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KEZ40175.1 - 0.012 16.0 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KEZ40175.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Fungal_trans_2 PF11951.3 KEZ40176.1 - 5e-27 94.4 0.1 3.7e-14 52.1 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40176.1 - 1.9e-07 30.8 11.3 3.3e-07 30.0 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KEZ40177.1 - 1.7e-17 63.1 5.7 2.1e-12 46.3 0.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Aminotran_3 PF00202.16 KEZ40178.1 - 3.7e-55 187.1 0.1 5.3e-55 186.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-III FAD_binding_3 PF01494.14 KEZ40179.1 - 5.2e-16 58.6 2.1 6.4e-15 55.0 1.5 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEZ40179.1 - 4.5e-05 23.7 2.6 4.8e-05 23.6 0.3 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ40179.1 - 0.00035 19.5 0.2 0.0014 17.6 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyrophosphatase PF00719.14 KEZ40179.1 - 0.0013 18.2 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Inorganic pyrophosphatase NAD_binding_8 PF13450.1 KEZ40179.1 - 0.025 14.6 0.2 0.07 13.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KEZ40179.1 - 0.041 13.3 0.2 0.076 12.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_61 PF03443.9 KEZ40180.1 - 2.5e-60 203.9 1.2 3.1e-60 203.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEZ40180.1 - 9.3e-13 47.5 11.7 2.8e-12 46.0 8.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Git3 PF11710.3 KEZ40181.1 - 5.3e-08 32.6 13.2 1.1e-07 31.6 9.2 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 KEZ40181.1 - 9e-07 28.0 10.2 9e-07 28.0 7.0 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KEZ40181.1 - 9.1e-07 28.2 5.5 1.2e-06 27.8 3.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HET PF06985.6 KEZ40181.1 - 3.2e-06 27.3 2.3 0.044 13.9 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) 7TM_GPCR_Srsx PF10320.4 KEZ40181.1 - 0.001 18.2 10.1 0.0017 17.5 7.0 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx 7tm_2 PF00002.19 KEZ40181.1 - 0.033 13.2 11.7 0.063 12.3 8.1 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Zn_clus PF00172.13 KEZ40182.1 - 2.4e-07 30.5 8.6 4.8e-07 29.5 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 KEZ40183.1 - 3.1e-05 23.6 0.0 6.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GST_N_3 PF13417.1 KEZ40184.1 - 2.9e-10 40.2 0.0 5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEZ40184.1 - 1.9e-07 31.1 0.0 6.2e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEZ40184.1 - 1.2e-05 25.1 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ40184.1 - 0.00036 20.3 0.1 0.00089 19.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEZ40184.1 - 0.00084 19.2 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEZ40185.1 - 8e-11 41.6 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEZ40185.1 - 2.4e-10 40.2 0.0 3.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEZ40185.1 - 2.8e-09 37.0 0.0 4.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEZ40185.1 - 3e-09 36.9 0.0 2.1e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEZ40185.1 - 2.7e-07 30.4 0.0 5.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEZ40185.1 - 1.8e-06 28.3 0.1 3.3e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MARVEL PF01284.18 KEZ40186.1 - 0.026 14.3 3.0 0.074 12.8 2.0 1.9 1 1 0 1 1 1 0 Membrane-associating domain PMI_typeI PF01238.16 KEZ40187.1 - 1.5e-45 155.7 0.0 1.4e-31 109.8 0.0 3.0 1 1 1 2 2 2 2 Phosphomannose isomerase type I Beta-lactamase PF00144.19 KEZ40187.1 - 4.3e-45 154.1 0.0 7e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KEZ40187.1 - 1.6e-06 27.8 0.2 8.2e-06 25.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) DUF3603 PF12227.3 KEZ40187.1 - 0.0069 15.5 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3603) MFS_1 PF07690.11 KEZ40188.1 - 6.3e-38 130.3 72.3 8.4e-32 110.2 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40188.1 - 9.7e-13 47.4 35.7 1.3e-08 33.8 9.2 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.1 KEZ40188.1 - 3.3e-06 25.7 20.2 3.3e-06 25.7 14.0 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KEZ40188.1 - 0.0023 17.6 2.3 0.058 13.1 0.3 2.9 2 0 0 2 2 2 1 MFS_1 like family HNH_2 PF13391.1 KEZ40190.1 - 1.3e-12 47.2 0.1 2.7e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease PGA_cap PF09587.5 KEZ40190.1 - 0.021 14.2 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap AP_endonuc_2 PF01261.19 KEZ40191.1 - 2.7e-28 98.7 0.0 4.5e-28 97.9 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel AAA_12 PF13087.1 KEZ40192.1 - 8.7e-24 84.0 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ40192.1 - 2.7e-12 46.7 0.0 5.7e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEZ40192.1 - 7.7e-06 25.6 0.0 0.0017 17.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KEZ40192.1 - 3.2e-05 23.5 2.1 0.19 11.1 0.1 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KEZ40192.1 - 0.00041 20.0 1.7 0.028 14.1 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain PepSY_2 PF13670.1 KEZ40193.1 - 0.018 14.9 1.7 3.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Chorion_3 PF05387.6 KEZ40193.1 - 0.54 9.6 8.2 0.68 9.3 5.7 1.0 1 0 0 1 1 1 0 Chorion family 3 TauD PF02668.11 KEZ40194.1 - 6.4e-42 143.9 0.0 7.9e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.4 KEZ40194.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain Plasmod_MYXSPDY PF07981.6 KEZ40194.1 - 0.077 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY MFS_1 PF07690.11 KEZ40195.1 - 1.7e-21 76.3 16.4 2.2e-21 75.9 11.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4383 PF14325.1 KEZ40195.1 - 1.7 8.6 7.5 0.48 10.4 1.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) Glyco_hydro_1 PF00232.13 KEZ40196.1 - 1.7e-133 445.2 0.2 2.3e-133 444.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sulfatase PF00884.18 KEZ40196.1 - 1.1e-58 198.8 0.6 1.9e-58 198.0 0.4 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEZ40196.1 - 0.034 13.4 0.4 0.23 10.7 0.0 2.4 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 KEZ40197.1 - 6.1e-43 146.8 32.7 2.2e-42 145.0 22.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40197.1 - 5.9e-10 38.3 9.1 5.9e-10 38.3 6.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Aminotran_1_2 PF00155.16 KEZ40198.1 - 4.7e-33 114.6 0.0 6.6e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEZ40198.1 - 0.0077 14.5 0.0 0.013 13.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 KEZ40198.1 - 0.023 13.2 0.0 0.049 12.1 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.16 KEZ40199.1 - 3e-40 138.1 0.0 3.8e-22 78.5 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KEZ40199.1 - 4.3e-34 117.8 0.0 7.9e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain BTB PF00651.26 KEZ40200.1 - 1e-07 31.9 0.0 3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain RsmJ PF04378.8 KEZ40201.1 - 0.12 11.2 0.1 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ Glyco_hydro_61 PF03443.9 KEZ40202.1 - 1.9e-80 269.7 0.0 2.4e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.17 KEZ40202.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF4470 PF14737.1 KEZ40203.1 - 1.4e-19 69.6 0.1 4.9e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) PSI_PsaH PF03244.9 KEZ40203.1 - 0.051 12.8 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI Fungal_lectin PF07938.7 KEZ40204.1 - 3.1e-64 217.1 10.5 3.8e-64 216.9 7.3 1.1 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF676 PF05057.9 KEZ40205.1 - 0.051 12.8 0.1 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA PF00004.24 KEZ40207.1 - 3.4e-09 37.0 0.1 9.2e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3425 PF11905.3 KEZ40208.1 - 1.7e-18 66.8 3.9 2.8e-18 66.1 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KEZ40208.1 - 0.0019 18.1 10.0 0.004 17.0 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ40208.1 - 0.16 11.8 12.4 0.28 11.0 8.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper ADH_zinc_N PF00107.21 KEZ40209.1 - 2.9e-25 88.2 0.2 4.9e-25 87.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ40209.1 - 4e-24 84.4 0.0 6.9e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 KEZ40209.1 - 0.048 12.8 0.1 0.082 12.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldedh PF00171.17 KEZ40210.1 - 8.4e-146 485.9 0.0 9.5e-146 485.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ40210.1 - 0.0093 14.7 0.0 0.23 10.1 0.0 2.0 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KEZ40210.1 - 0.028 13.6 0.0 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SnoaL_2 PF12680.2 KEZ40211.1 - 2.5e-05 24.6 0.0 3.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 KEZ40211.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Pyr_redox_3 PF13738.1 KEZ40212.1 - 8.9e-21 74.8 0.0 3.7e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ40212.1 - 2.9e-13 49.6 0.0 6.4e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KEZ40212.1 - 3.6e-13 48.5 0.1 4.1e-10 38.4 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KEZ40212.1 - 4.3e-06 26.7 0.0 0.001 18.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ40212.1 - 7.7e-06 25.7 4.1 0.00093 19.0 0.0 3.9 3 2 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 KEZ40212.1 - 0.00045 19.2 0.0 0.06 12.2 0.0 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEZ40212.1 - 0.00079 18.4 0.0 0.84 8.4 0.0 3.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KEZ40212.1 - 0.00082 18.5 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KEZ40212.1 - 0.0076 14.7 0.0 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 KEZ40212.1 - 0.013 14.8 0.1 0.048 13.1 0.0 2.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA DEDD_Tnp_IS110 PF01548.12 KEZ40212.1 - 0.079 12.6 0.0 6.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Transposase Lycopene_cycl PF05834.7 KEZ40212.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KEZ40212.1 - 0.16 10.7 0.0 0.42 9.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 KEZ40213.1 - 1.6e-31 109.3 30.3 2.4e-31 108.7 21.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 KEZ40214.1 - 5.7e-63 213.0 0.0 6.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.6 KEZ40215.1 - 1.9e-22 79.9 0.0 4.9e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAA_hydrolase PF01557.13 KEZ40216.1 - 6.1e-62 208.9 0.0 7.6e-62 208.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 KEZ40216.1 - 0.064 13.6 0.1 0.26 11.7 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2437) Transferase PF02458.10 KEZ40218.1 - 0.013 13.9 0.0 0.022 13.2 0.0 1.4 1 0 0 1 1 1 0 Transferase family PLDc_2 PF13091.1 KEZ40218.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 PLD-like domain COX2 PF00116.15 KEZ40218.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain OPT PF03169.10 KEZ40220.1 - 2.5e-134 449.0 48.6 2.9e-134 448.8 33.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 KEZ40221.1 - 1.2e-31 109.7 21.7 1.2e-31 109.7 15.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ40221.1 - 0.00022 19.5 0.9 0.00036 18.8 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_3 PF13738.1 KEZ40222.1 - 6.4e-27 94.9 0.0 5.7e-25 88.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ40222.1 - 5.6e-14 52.4 0.0 9.5e-11 41.9 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ40222.1 - 3.2e-13 48.7 0.2 3.2e-12 45.4 0.2 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ40222.1 - 9.8e-13 47.7 0.5 1.4e-08 34.0 0.1 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KEZ40222.1 - 2.2e-10 40.7 0.1 0.00082 19.7 0.0 3.6 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ40222.1 - 2.4e-08 33.2 2.4 0.00049 19.1 0.2 3.6 3 1 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEZ40222.1 - 8.1e-08 31.7 1.8 1.4e-06 27.6 0.2 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ40222.1 - 4.1e-07 29.9 0.0 1.4e-05 25.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEZ40222.1 - 4.4e-06 26.5 2.1 0.66 9.7 0.1 3.4 2 1 1 3 3 3 3 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KEZ40222.1 - 1.7e-05 24.9 0.1 0.24 11.5 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 KEZ40222.1 - 9.6e-05 21.3 1.3 0.0016 17.3 0.3 2.9 1 1 3 4 4 4 1 FAD binding domain HI0933_like PF03486.9 KEZ40222.1 - 0.0022 16.5 0.1 0.033 12.6 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 KEZ40222.1 - 0.0047 16.0 0.2 0.11 11.5 0.0 2.8 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KEZ40222.1 - 0.005 15.8 0.2 0.043 12.7 0.0 2.4 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_oxidored PF12831.2 KEZ40222.1 - 0.0053 15.8 1.9 0.083 11.9 1.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KEZ40222.1 - 0.011 15.9 0.0 6.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 KEZ40222.1 - 0.045 12.6 0.0 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KEZ40222.1 - 0.07 12.2 0.2 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 KEZ40222.1 - 0.11 12.1 0.1 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sugar_tr PF00083.19 KEZ40223.1 - 3.9e-46 157.5 20.2 5.3e-46 157.1 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ40223.1 - 3.1e-21 75.4 40.6 4.6e-20 71.6 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KEZ40224.1 - 6.5e-15 54.7 61.8 1.9e-13 49.8 21.5 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 KEZ40224.1 - 0.012 13.8 24.8 0.018 13.2 17.2 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) ABC_tran PF00005.22 KEZ40225.1 - 1.7e-50 170.9 0.0 1.5e-29 103.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ40225.1 - 1.7e-26 93.2 24.0 2.3e-22 79.6 5.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KEZ40225.1 - 6e-12 45.2 3.0 8.2e-05 21.9 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ40225.1 - 1e-09 38.7 0.3 0.11 12.4 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 KEZ40225.1 - 2e-08 34.4 0.1 0.0056 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KEZ40225.1 - 6.7e-08 31.9 0.8 0.0017 17.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 KEZ40225.1 - 3.8e-07 29.8 0.4 0.0022 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 KEZ40225.1 - 4.2e-07 29.2 0.2 0.0036 16.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KEZ40225.1 - 7.5e-07 29.6 0.1 0.021 15.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 KEZ40225.1 - 2.3e-06 27.7 2.2 0.042 13.9 0.0 4.0 3 2 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KEZ40225.1 - 5.8e-06 26.2 0.2 0.18 11.7 0.0 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 KEZ40225.1 - 7.3e-06 25.9 0.0 0.041 13.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEZ40225.1 - 3.2e-05 23.4 0.0 0.082 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KEZ40225.1 - 7.8e-05 22.5 0.1 0.017 15.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 KEZ40225.1 - 0.00019 22.2 1.1 0.65 10.8 0.2 2.8 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 KEZ40225.1 - 0.00021 20.8 0.1 0.04 13.3 0.0 2.9 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KEZ40225.1 - 0.00039 20.1 0.6 0.32 10.7 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KEZ40225.1 - 0.00062 19.3 0.2 0.53 9.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family ArgK PF03308.11 KEZ40225.1 - 0.0009 18.0 0.2 0.79 8.4 0.1 2.4 2 0 0 2 2 2 2 ArgK protein NB-ARC PF00931.17 KEZ40225.1 - 0.00099 18.0 2.0 5.3 5.8 0.0 3.6 3 1 0 3 3 3 0 NB-ARC domain AAA_23 PF13476.1 KEZ40225.1 - 0.0012 19.2 1.2 0.03 14.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEZ40225.1 - 0.0016 17.5 0.8 0.59 9.1 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin T2SE PF00437.15 KEZ40225.1 - 0.0022 16.9 0.2 0.018 13.9 0.0 2.3 3 0 0 3 3 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 KEZ40225.1 - 0.0028 17.9 0.9 3.4 7.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain KaiC PF06745.8 KEZ40225.1 - 0.0029 16.7 1.0 0.14 11.2 0.1 3.0 2 1 0 2 2 2 1 KaiC AAA PF00004.24 KEZ40225.1 - 0.0032 17.6 1.7 3.6 7.7 0.1 4.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 KEZ40225.1 - 0.0039 16.2 0.4 1.8 7.5 0.0 2.3 2 0 0 2 2 2 1 Septin NACHT PF05729.7 KEZ40225.1 - 0.0042 16.7 0.1 0.7 9.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ATP_bind_1 PF03029.12 KEZ40225.1 - 0.0061 16.1 0.1 0.81 9.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 KEZ40225.1 - 0.0065 15.9 0.0 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 KEZ40225.1 - 0.0072 16.0 0.6 11 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KEZ40225.1 - 0.0077 14.8 0.3 0.19 10.2 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 KEZ40225.1 - 0.013 15.3 1.5 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 KEZ40225.1 - 0.017 15.3 0.2 12 6.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Adeno_IVa2 PF02456.10 KEZ40225.1 - 0.02 13.5 0.0 0.094 11.3 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 KEZ40225.1 - 0.03 14.0 0.8 0.45 10.1 0.0 2.7 3 0 0 3 3 3 0 Archaeal ATPase ABC_ATPase PF09818.4 KEZ40225.1 - 0.034 12.7 3.1 2.6 6.5 0.3 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class GTP_EFTU PF00009.22 KEZ40225.1 - 0.037 13.4 0.1 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEZ40225.1 - 0.042 13.6 1.7 0.74 9.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family PRK PF00485.13 KEZ40225.1 - 0.22 11.0 0.3 0.69 9.4 0.1 2.0 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 KEZ40225.1 - 0.23 11.1 1.9 9.2 5.9 0.1 2.7 3 0 0 3 3 2 0 NTPase Guanylate_kin PF00625.16 KEZ40225.1 - 0.26 10.7 0.1 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase AAA_PrkA PF08298.6 KEZ40225.1 - 0.27 9.8 0.1 13 4.3 0.0 3.0 3 0 0 3 3 3 0 PrkA AAA domain AAA_24 PF13479.1 KEZ40225.1 - 0.28 10.7 1.5 10 5.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain Aminotran_4 PF01063.14 KEZ40226.1 - 2.7e-14 53.1 0.0 3.7e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 KEZ40227.1 - 4.4e-64 216.7 0.0 6e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 KEZ40228.1 - 5.3e-43 147.0 8.2 9.6e-43 146.2 5.7 1.3 1 1 0 1 1 1 1 RTA1 like protein DUF3309 PF11752.3 KEZ40228.1 - 0.0045 16.7 1.4 0.016 14.9 1.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3309) DUF1282 PF06930.7 KEZ40228.1 - 2.9 7.5 16.4 9.4 5.8 3.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1282) Ank_2 PF12796.2 KEZ40229.1 - 1.4e-08 34.9 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ40229.1 - 2e-08 34.4 0.0 4.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ40229.1 - 1.4e-06 28.3 0.0 0.08 13.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40229.1 - 1.4e-05 24.8 0.0 0.064 13.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 KEZ40229.1 - 4.7e-05 22.9 0.1 0.25 11.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Sec2p PF06428.6 KEZ40229.1 - 0.071 12.9 0.6 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p RAP1 PF07218.6 KEZ40229.1 - 0.35 8.9 3.0 0.48 8.4 2.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) bZIP_1 PF00170.16 KEZ40229.1 - 5.1 7.1 13.8 13 5.8 9.5 1.6 1 1 0 1 1 1 0 bZIP transcription factor AMP-binding PF00501.23 KEZ40230.1 - 0 1067.7 1.4 2.2e-86 289.8 0.0 4.8 5 0 0 5 5 5 4 AMP-binding enzyme Condensation PF00668.15 KEZ40230.1 - 1.2e-240 796.0 0.0 3.5e-47 160.7 0.0 8.1 8 2 0 8 8 8 6 Condensation domain PP-binding PF00550.20 KEZ40230.1 - 1.2e-36 124.7 0.4 8e-09 35.6 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEZ40230.1 - 1.3e-23 83.6 0.1 8.9e-05 23.3 0.0 5.0 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain AATase PF07247.7 KEZ40230.1 - 0.0001 20.9 0.1 4.2 5.8 0.0 5.2 6 1 0 6 6 6 1 Alcohol acetyltransferase HxxPF_rpt PF13745.1 KEZ40230.1 - 0.0042 17.3 0.0 0.026 14.8 0.0 2.5 1 0 0 1 1 1 1 HxxPF-repeated domain Transferase PF02458.10 KEZ40230.1 - 0.11 10.9 0.0 1.6 7.0 0.0 2.6 3 0 0 3 3 3 0 Transferase family Stork_head PF10264.4 KEZ40230.1 - 0.22 11.7 0.1 6 7.1 0.0 2.8 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Pkinase PF00069.20 KEZ40231.1 - 0.041 13.0 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Dynamin_N PF00350.18 KEZ40233.1 - 8.6e-14 51.7 0.2 1.7e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEZ40233.1 - 7e-11 41.4 0.0 1.9e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KEZ40233.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase adh_short PF00106.20 KEZ40233.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DAP_C PF07932.7 KEZ40234.1 - 0.062 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain C ANF_receptor PF01094.23 KEZ40234.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region Spc7 PF08317.6 KEZ40235.1 - 0.00055 18.7 2.7 0.0011 17.7 1.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein PHTB1_C PF14728.1 KEZ40235.1 - 0.032 13.0 1.2 0.053 12.3 0.8 1.4 1 0 0 1 1 1 0 PTHB1 C-terminus DUF3538 PF12057.3 KEZ40235.1 - 0.042 13.4 0.2 0.042 13.4 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3538) Med11 PF10280.4 KEZ40235.1 - 0.046 13.7 0.8 0.22 11.5 0.0 2.1 2 1 0 2 2 2 0 Mediator complex protein DUF1116 PF06545.6 KEZ40235.1 - 0.054 12.5 0.1 0.11 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) DUF4446 PF14584.1 KEZ40235.1 - 0.31 10.8 6.2 7.7 6.3 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF972 PF06156.8 KEZ40235.1 - 0.33 11.2 9.3 0.49 10.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 KEZ40235.1 - 0.82 8.8 8.5 0.055 12.6 1.9 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding LCD1 PF09798.4 KEZ40235.1 - 1.1 7.2 4.4 1.6 6.6 3.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein MxiH PF09392.5 KEZ40235.1 - 2.7 8.5 5.2 16 6.1 1.2 2.8 2 1 0 2 2 2 0 Type III secretion needle MxiH like DUF4363 PF14276.1 KEZ40236.1 - 6 6.6 10.3 0.58 9.8 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) 2-Hacid_dh_C PF02826.14 KEZ40237.1 - 1.3e-51 174.3 0.0 5e-51 172.3 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KEZ40237.1 - 3.3e-28 98.2 0.0 5.6e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh PF00389.25 KEZ40237.1 - 8e-19 67.4 0.0 1.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Zn_clus PF00172.13 KEZ40237.1 - 2e-06 27.6 10.3 2e-06 27.6 7.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_2 PF03446.10 KEZ40237.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KEZ40237.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NB-ARC PF00931.17 KEZ40238.1 - 2.4e-08 33.1 0.0 4.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.12 KEZ40238.1 - 1.5e-06 27.7 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KEZ40238.1 - 0.0024 18.0 0.0 0.0067 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ40238.1 - 0.0079 16.2 0.3 0.072 13.0 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 KEZ40238.1 - 0.034 12.9 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Chitin_synth_1 PF01644.12 KEZ40238.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Chitin synthase AAA_25 PF13481.1 KEZ40238.1 - 0.076 12.4 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEZ40238.1 - 0.086 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEZ40238.1 - 0.17 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Nucleoplasmin PF03066.10 KEZ40238.1 - 0.32 10.5 5.1 0.65 9.4 3.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin OPT PF03169.10 KEZ40239.1 - 2.7e-84 283.7 42.0 3.1e-84 283.5 29.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NACHT PF05729.7 KEZ40240.1 - 6e-10 39.0 0.6 1.1e-08 34.9 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 KEZ40240.1 - 3.9e-05 23.7 0.2 0.00028 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ40240.1 - 0.00013 22.0 0.0 0.00065 19.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KEZ40240.1 - 0.0093 15.4 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 KEZ40240.1 - 0.013 14.3 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KEZ40240.1 - 0.016 15.5 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KEZ40240.1 - 0.019 15.2 0.2 0.43 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEZ40240.1 - 0.019 15.7 3.2 0.035 14.9 0.2 3.0 2 1 1 3 3 2 0 AAA domain AAA_18 PF13238.1 KEZ40240.1 - 0.021 15.1 0.0 0.091 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEZ40240.1 - 0.04 13.5 0.1 0.46 10.1 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 KEZ40240.1 - 0.086 12.2 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KEZ40240.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ40240.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 KEZ40240.1 - 0.16 11.5 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KEZ40240.1 - 0.17 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 KEZ40240.1 - 0.34 9.8 2.4 8.7 5.2 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain DUF87 PF01935.12 KEZ40240.1 - 0.36 10.6 2.3 5.7 6.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 LysM PF01476.15 KEZ40242.1 - 1.4e-35 120.9 12.0 7.2e-07 28.9 0.0 5.2 5 0 0 5 5 5 5 LysM domain HTH_Tnp_1 PF01527.15 KEZ40242.1 - 2.6e-05 24.0 0.1 0.65 9.9 0.0 3.5 3 0 0 3 3 3 2 Transposase Cmc1 PF08583.5 KEZ40242.1 - 0.014 15.1 0.0 11 5.8 0.0 3.6 3 0 0 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pox_A11 PF05061.8 KEZ40242.1 - 0.16 10.9 1.2 11 4.9 0.0 3.3 4 0 0 4 4 4 0 Poxvirus A11 Protein UL40 PF10682.4 KEZ40242.1 - 0.17 11.3 2.5 0.79 9.1 0.7 2.5 2 1 0 2 2 2 0 Glycoprotein of human cytomegalovirus HHV-5 UPF0203 PF05254.7 KEZ40242.1 - 0.5 10.2 11.0 12 5.7 0.0 4.3 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0203) COX6B PF02297.12 KEZ40242.1 - 0.6 10.1 4.6 16 5.5 0.1 3.5 4 0 0 4 4 4 0 Cytochrome oxidase c subunit VIb Glyco_hydro_18 PF00704.23 KEZ40243.1 - 2.7e-49 168.4 0.1 4.2e-49 167.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 KEZ40243.1 - 3.9e-28 97.2 3.1 6.8e-28 96.4 0.4 2.4 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 KEZ40243.1 - 0.00031 20.5 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KEZ40243.1 - 0.00077 19.3 2.6 0.00077 19.3 1.8 3.5 4 0 0 4 4 4 1 Chitin recognition protein DUF3142 PF11340.3 KEZ40243.1 - 0.22 11.1 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) SecE PF00584.15 KEZ40244.1 - 2.6e-12 46.1 0.0 2.8e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_S3Ae PF01015.13 KEZ40245.1 - 6e-82 273.7 4.6 7.2e-82 273.4 3.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 KEZ40245.1 - 0.053 13.6 0.9 0.6 10.2 0.0 2.6 2 1 1 3 3 3 0 Syntaxin SCO1-SenC PF02630.9 KEZ40245.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC GTP_CH_N PF12471.3 KEZ40246.1 - 5.5e-69 231.7 0.0 8.9e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KEZ40246.1 - 1.7e-09 37.1 0.0 3.5e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.8 KEZ40247.1 - 7.2e-27 92.8 0.0 9e-27 92.5 0.0 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.1 KEZ40247.1 - 0.22 11.3 1.3 0.36 10.6 0.9 1.5 1 1 0 1 1 1 0 Cysteine-rich CPXCG zf-C2H2_6 PF13912.1 KEZ40247.1 - 4.1 7.4 6.3 1.3 9.0 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger WAPL PF07814.8 KEZ40248.1 - 1.1e-12 47.3 0.2 8.1e-10 37.9 0.0 2.2 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin tRNA-synt_2b PF00587.20 KEZ40249.1 - 8.2e-35 119.9 0.0 1.4e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KEZ40249.1 - 6.9e-18 64.6 3.4 6.9e-18 64.6 2.3 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain SYCE1 PF15233.1 KEZ40249.1 - 0.031 14.1 2.0 0.07 13.0 1.4 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Ham1p_like PF01725.11 KEZ40250.1 - 4.6e-40 137.0 0.0 9.7e-40 135.9 0.0 1.5 1 1 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 KEZ40251.1 - 1.5e-28 99.6 0.2 5.9e-28 97.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ40251.1 - 7.2e-16 59.0 1.8 7.3e-15 55.8 1.3 2.0 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KEZ40251.1 - 6.4e-05 22.8 0.3 0.0069 16.2 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase SKI PF01202.17 KEZ40251.1 - 0.00014 21.7 0.1 0.00097 19.0 0.1 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_28 PF13521.1 KEZ40251.1 - 0.00016 21.6 0.0 0.00053 19.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEZ40251.1 - 0.00021 21.2 0.0 0.062 13.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KEZ40251.1 - 0.00047 20.3 0.0 0.005 17.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 KEZ40251.1 - 0.0013 18.1 0.1 1 8.6 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase NTPase_1 PF03266.10 KEZ40251.1 - 0.0013 18.4 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 NTPase KTI12 PF08433.5 KEZ40251.1 - 0.016 14.3 0.0 0.045 12.9 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 KEZ40251.1 - 0.019 14.9 0.1 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KEZ40251.1 - 0.024 14.7 0.1 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 KEZ40251.1 - 0.024 14.5 0.1 0.081 12.8 0.0 1.8 2 1 0 2 2 2 0 Cytidylate kinase-like family dNK PF01712.14 KEZ40251.1 - 0.026 14.4 0.4 0.035 14.0 0.3 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_10 PF12846.2 KEZ40251.1 - 0.027 13.8 0.0 0.076 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 KEZ40251.1 - 0.028 13.9 0.3 0.058 12.9 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 KEZ40251.1 - 0.04 13.6 0.1 0.095 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEZ40251.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KEZ40251.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ArgK PF03308.11 KEZ40251.1 - 0.11 11.1 0.2 0.29 9.8 0.0 1.7 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 KEZ40251.1 - 0.12 11.8 0.3 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KEZ40251.1 - 0.13 12.4 0.1 0.26 11.4 0.0 1.5 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.1 KEZ40251.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPP_enzyme_C PF02775.16 KEZ40253.1 - 8.3e-10 38.4 0.0 1.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ40253.1 - 0.0012 18.5 0.1 0.002 17.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_4 PF01565.18 KEZ40254.1 - 6.8e-24 83.9 0.0 1.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KEZ40255.1 - 2.5e-19 69.2 52.6 2.5e-16 59.3 19.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ40255.1 - 4.2e-14 51.6 15.7 3.3e-13 48.7 10.9 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) O-ag_pol_Wzy PF14296.1 KEZ40256.1 - 0.038 12.5 0.1 0.15 10.6 0.0 1.8 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy FAD_binding_4 PF01565.18 KEZ40257.1 - 1.2e-28 99.2 0.0 2.2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KEZ40257.1 - 8.2e-05 22.0 0.1 0.00025 20.4 0.1 1.7 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain TylF PF05711.6 KEZ40257.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DLH PF01738.13 KEZ40258.1 - 7.2e-19 67.9 0.0 2.5e-18 66.1 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ40258.1 - 9.4e-09 35.1 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ40258.1 - 3.4e-05 23.8 0.0 0.043 13.6 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ40258.1 - 0.0085 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family TrpBP PF02081.10 KEZ40258.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein Ank_2 PF12796.2 KEZ40259.1 - 1.9e-94 310.1 11.9 2.7e-14 53.2 0.0 5.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ40259.1 - 4.1e-40 133.6 10.6 2.6e-05 23.7 0.0 11.4 11 0 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.1 KEZ40259.1 - 4.1e-35 119.5 1.9 7.5e-08 32.6 0.0 7.5 2 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ40259.1 - 1.9e-33 113.7 3.0 2e-07 31.0 0.1 7.2 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40259.1 - 3.4e-32 107.2 0.0 0.0013 18.8 0.0 11.2 11 0 0 11 11 11 6 Ankyrin repeat DUF2773 PF10971.3 KEZ40259.1 - 0.12 12.3 0.9 27 4.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2773) FAD_binding_3 PF01494.14 KEZ40260.1 - 1e-88 297.8 0.0 1.3e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEZ40260.1 - 2.8e-55 186.4 0.0 4.8e-55 185.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 KEZ40260.1 - 8.8e-05 21.7 0.1 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KEZ40260.1 - 0.00021 20.2 0.2 0.00034 19.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ40260.1 - 0.00033 19.2 0.3 0.00061 18.3 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ40260.1 - 0.00049 20.0 0.8 0.0013 18.6 0.2 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ40260.1 - 0.009 14.9 0.1 0.02 13.8 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KEZ40260.1 - 0.03 13.2 0.1 0.074 11.9 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KEZ40260.1 - 0.045 12.6 0.2 0.079 11.8 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KEZ40260.1 - 0.055 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ40260.1 - 0.081 12.9 0.2 0.33 11.0 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 KEZ40260.1 - 0.096 12.0 0.1 1.9 7.8 0.1 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 KEZ40260.1 - 0.12 11.4 0.3 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Dioxygenase_C PF00775.16 KEZ40261.1 - 1.6e-57 193.7 0.0 2.1e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEZ40261.1 - 2.3e-12 46.7 0.0 3.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEZ40261.1 - 2.4e-06 27.4 0.0 0.00012 22.0 0.0 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 KEZ40261.1 - 0.0011 19.0 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) DUF2824 PF11039.3 KEZ40261.1 - 0.038 13.6 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) CoA_transf_3 PF02515.12 KEZ40262.1 - 3.7e-31 107.8 0.0 1.4e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III TRI5 PF06330.6 KEZ40263.1 - 3e-10 39.2 0.0 4.4e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) EcKinase PF02958.15 KEZ40264.1 - 1.5e-18 67.0 0.0 1.7e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 KEZ40264.1 - 3.2e-08 33.5 1.0 4.9e-08 32.9 0.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KEZ40264.1 - 9.5e-08 31.0 0.1 1.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) OTT_1508_deam PF14441.1 KEZ40266.1 - 0.00065 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase F-box PF00646.28 KEZ40266.1 - 0.0023 17.5 0.0 0.011 15.3 0.0 2.3 1 0 0 1 1 1 1 F-box domain SDA1 PF05285.7 KEZ40266.1 - 1 8.5 14.6 1.6 7.9 10.1 1.2 1 0 0 1 1 1 0 SDA1 OCD_Mu_crystall PF02423.10 KEZ40267.1 - 1.8e-15 56.5 0.5 4.1e-10 38.9 0.4 2.8 1 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KEZ40267.1 - 8.1e-06 25.9 0.0 7.4e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KEZ40267.1 - 0.0095 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 KEZ40267.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Thiolase_N PF00108.18 KEZ40268.1 - 1.7e-75 253.4 4.5 2.4e-75 252.9 3.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEZ40268.1 - 5.6e-42 142.0 0.2 1.2e-41 141.0 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KEZ40268.1 - 0.023 14.6 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 KEZ40268.1 - 0.63 9.4 6.7 0.46 9.9 1.4 2.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain PEMT PF04191.8 KEZ40269.1 - 1.2e-30 105.7 3.5 2.2e-30 104.8 2.4 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase AsnC_trans_reg PF01037.16 KEZ40272.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AsnC family Flavokinase PF01687.12 KEZ40273.1 - 3.9e-37 126.9 0.0 7.9e-37 125.9 0.0 1.5 2 0 0 2 2 2 1 Riboflavin kinase PAS PF00989.19 KEZ40274.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 KEZ40274.1 - 0.0036 17.1 8.9 0.0036 17.1 6.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 KEZ40275.1 - 1e-10 41.2 0.2 1e-10 41.2 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Synaptobrevin PF00957.16 KEZ40275.1 - 0.0023 17.4 1.5 0.0041 16.6 1.1 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1191 PF06697.7 KEZ40275.1 - 0.15 10.8 0.2 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Transket_pyr PF02779.19 KEZ40276.1 - 5.3e-44 149.8 0.1 8e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEZ40276.1 - 5.6e-32 110.2 0.0 1.7e-31 108.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain NMO PF03060.10 KEZ40277.1 - 2.1e-63 214.4 0.3 3.1e-63 213.9 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KEZ40277.1 - 4.3e-11 42.3 0.0 0.0002 20.3 0.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEZ40277.1 - 0.0034 16.2 0.3 0.0058 15.5 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KEZ40277.1 - 0.063 12.5 0.3 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NIL PF09383.5 KEZ40277.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 NIL domain DUF561 PF04481.7 KEZ40277.1 - 0.15 10.9 0.2 0.8 8.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF561) Pkinase PF00069.20 KEZ40278.1 - 2.2e-25 89.3 0.0 3.9e-18 65.5 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40278.1 - 9.9e-06 24.7 0.0 0.11 11.5 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase Ribosomal_S7 PF00177.16 KEZ40279.1 - 4.8e-26 91.1 0.0 7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Usp PF00582.21 KEZ40280.1 - 5.3e-19 68.7 6.4 4.7e-13 49.5 0.3 3.6 3 1 0 3 3 3 2 Universal stress protein family SseB_C PF14581.1 KEZ40280.1 - 0.053 13.3 0.2 13 5.6 0.0 2.6 2 0 0 2 2 2 0 SseB protein C-terminal domain Caveolin PF01146.12 KEZ40280.1 - 0.22 11.0 0.1 0.39 10.2 0.1 1.3 1 0 0 1 1 1 0 Caveolin RRM_1 PF00076.17 KEZ40282.1 - 4e-84 276.2 6.1 2.5e-23 81.4 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ40282.1 - 1e-54 182.4 0.9 5.2e-15 55.1 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ40282.1 - 2.9e-41 139.1 0.3 3e-10 39.7 0.0 5.5 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KEZ40282.1 - 6.6e-27 92.9 3.1 1.7e-26 91.6 1.2 2.4 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 KEZ40282.1 - 2.5e-05 23.9 0.6 4.6 7.0 0.0 4.9 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEZ40282.1 - 3.8e-05 23.3 1.6 0.29 10.9 0.1 3.4 3 0 0 3 3 3 2 Limkain b1 CbiG_mid PF11761.3 KEZ40282.1 - 0.0043 17.2 0.1 3.3 7.9 0.0 3.2 2 0 0 2 2 2 1 Cobalamin biosynthesis central region Nab6_mRNP_bdg PF10567.4 KEZ40282.1 - 0.026 13.5 0.0 0.074 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA-recognition motif OB_RNB PF08206.6 KEZ40282.1 - 0.078 12.4 0.8 26 4.4 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 KEZ40283.1 - 9.5e-81 271.3 0.0 1.5e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1237 PF06824.6 KEZ40284.1 - 6.3e-167 555.4 0.0 7.2e-167 555.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Glyco_hydro_92 PF07971.7 KEZ40285.1 - 9.2e-170 565.5 0.1 1.1e-169 565.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ETF_QO PF05187.8 KEZ40286.1 - 1.3e-43 147.4 0.0 2e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 KEZ40286.1 - 1.2e-09 37.5 0.0 9.1e-05 21.5 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ40286.1 - 3.7e-08 33.2 0.0 2.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ40286.1 - 2.8e-05 23.1 0.5 0.0028 16.5 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KEZ40286.1 - 3.6e-05 22.9 0.0 0.00089 18.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ40286.1 - 8.2e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ40286.1 - 9.9e-05 21.5 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ40286.1 - 0.00018 20.0 0.5 0.00028 19.5 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KEZ40286.1 - 0.00019 21.7 0.1 0.77 10.2 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ40286.1 - 0.00021 20.4 0.1 0.00035 19.7 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KEZ40286.1 - 0.0031 17.3 0.1 0.0059 16.3 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KEZ40286.1 - 0.0034 16.0 0.0 0.086 11.4 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KEZ40286.1 - 0.0037 17.3 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KEZ40286.1 - 0.0079 16.5 0.6 0.023 15.0 0.4 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 KEZ40286.1 - 0.015 14.2 0.2 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KEZ40286.1 - 0.053 12.3 0.1 0.077 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.16 KEZ40287.1 - 2.7e-70 231.7 0.1 4.3e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KEZ40287.1 - 0.00022 21.1 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 KEZ40287.1 - 0.003 17.9 0.6 0.0045 17.3 0.4 1.4 1 0 0 1 1 1 1 Ribonuclease (pollen allergen) Fungal_trans PF04082.13 KEZ40288.1 - 0.00054 18.9 0.1 0.002 17.0 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyoxalase PF00903.20 KEZ40290.1 - 9.6e-39 132.2 0.1 1.3e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEZ40290.1 - 5.6e-33 113.7 0.0 1.6e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KEZ40290.1 - 5.4e-19 68.2 0.0 5.7e-06 26.2 0.0 3.9 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KEZ40290.1 - 6.3e-05 22.9 0.0 0.72 9.7 0.0 3.2 2 1 1 3 3 3 2 Glyoxalase-like domain TRI9 PF08195.6 KEZ40290.1 - 0.066 12.8 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 TRI9 protein 2-Hacid_dh_C PF02826.14 KEZ40291.1 - 2.4e-54 183.2 0.1 3.8e-54 182.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEZ40291.1 - 2.3e-35 120.9 0.5 5.3e-35 119.7 0.3 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 KEZ40291.1 - 0.013 14.9 0.3 0.066 12.7 0.0 2.5 2 0 0 2 2 2 0 ACT domain AdoHcyase_NAD PF00670.16 KEZ40291.1 - 0.019 14.7 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KEZ40291.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain XdhC_C PF13478.1 KEZ40291.1 - 0.048 13.9 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 KEZ40291.1 - 0.067 12.7 0.8 0.17 11.4 0.6 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF21 PF01595.15 KEZ40292.1 - 1.8e-31 108.8 0.9 2.9e-31 108.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KEZ40292.1 - 3e-06 26.9 0.0 0.038 13.7 0.0 3.0 1 1 1 2 2 2 2 CBS domain DUF500 PF04366.7 KEZ40293.1 - 1.3e-44 150.7 0.2 1.9e-44 150.0 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KEZ40293.1 - 1.6e-15 56.2 0.0 3.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ40293.1 - 2.3e-13 49.5 0.0 3.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEZ40293.1 - 9.1e-13 47.4 0.0 1.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Synaptobrevin PF00957.16 KEZ40294.1 - 0.0073 15.8 0.9 0.26 10.9 0.1 2.0 1 1 1 2 2 2 2 Synaptobrevin SNARE PF05739.14 KEZ40294.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.3 1 1 0 1 1 1 0 SNARE domain LPP PF04728.8 KEZ40294.1 - 0.05 13.4 0.5 0.1 12.4 0.3 1.5 1 1 0 1 1 1 0 Lipoprotein leucine-zipper DUF2207 PF09972.4 KEZ40294.1 - 0.067 11.7 0.1 0.073 11.6 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ArfGap PF01412.13 KEZ40295.1 - 5e-42 142.3 0.9 7.6e-42 141.7 0.6 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.13 KEZ40296.1 - 1.6e-49 166.7 0.1 1.9e-49 166.4 0.1 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.9 KEZ40296.1 - 0.053 13.5 0.2 0.14 12.2 0.2 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 KEZ40296.1 - 0.061 13.1 2.8 2.8 7.8 2.4 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF2296 PF10058.4 KEZ40296.1 - 0.095 12.4 0.3 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) ARID PF01388.16 KEZ40297.1 - 1e-17 63.7 0.0 2.2e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain KH_1 PF00013.24 KEZ40298.1 - 2.7e-92 302.3 36.8 4e-13 48.7 0.5 13.2 14 1 0 14 14 14 9 KH domain KH_3 PF13014.1 KEZ40298.1 - 5.3e-63 207.8 27.5 4.7e-10 38.8 0.1 13.4 13 0 0 13 13 13 9 KH domain KH_2 PF07650.12 KEZ40298.1 - 3.7e-11 42.4 23.5 0.029 13.9 0.0 8.1 8 0 0 8 8 8 4 KH domain SLS PF14611.1 KEZ40298.1 - 1.7e-08 34.1 10.6 0.00085 18.8 0.0 6.6 5 3 2 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 KEZ40298.1 - 0.0028 17.2 0.2 0.0028 17.2 0.1 5.6 7 0 0 7 7 7 1 KH domain DDOST_48kD PF03345.9 KEZ40298.1 - 0.26 9.7 0.1 0.56 8.6 0.1 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Pkinase PF00069.20 KEZ40299.1 - 7.8e-70 234.9 0.0 1.1e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40299.1 - 7.4e-46 156.3 0.0 1.1e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ40299.1 - 1.3e-06 27.6 0.0 2.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 KEZ40299.1 - 1.2e-05 25.6 0.6 0.00011 22.5 0.4 2.7 1 1 0 1 1 1 1 P21-Rho-binding domain APH PF01636.18 KEZ40299.1 - 0.041 13.6 0.3 0.14 11.8 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 KEZ40299.1 - 0.24 10.6 0.0 0.45 9.7 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain VHS PF00790.14 KEZ40300.1 - 3.9e-41 139.9 3.2 1.8e-40 137.8 0.1 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KEZ40300.1 - 1.1e-15 57.2 4.6 1.9e-15 56.4 3.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KEZ40300.1 - 2.2e-05 23.6 15.2 0.0043 16.5 1.1 2.9 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KEZ40300.1 - 0.0071 15.7 1.7 0.0071 15.7 1.2 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase UCH PF00443.24 KEZ40301.1 - 3.9e-33 114.7 0.5 6.1e-33 114.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ40301.1 - 9.2e-23 81.1 0.0 2.5e-22 79.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KEZ40301.1 - 9.5e-07 29.1 0.0 2.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain CDK5_activator PF03261.10 KEZ40301.1 - 0.79 8.9 4.4 1.5 8.1 3.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AMP-binding PF00501.23 KEZ40302.1 - 1.1e-77 261.1 0.0 1.5e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HSP70 PF00012.15 KEZ40303.1 - 1.8e-268 891.4 11.3 2.1e-268 891.2 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ40303.1 - 2.3e-17 62.5 3.8 2.9e-16 58.9 0.8 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 KEZ40303.1 - 0.024 13.7 5.1 0.054 12.5 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KEZ40303.1 - 0.8 9.5 8.4 4.8 7.0 1.0 3.4 2 2 0 2 2 2 0 Cell division protein FtsA GTP_EFTU PF00009.22 KEZ40304.1 - 3.9e-48 163.3 0.1 9.2e-48 162.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KEZ40304.1 - 1.8e-22 79.2 1.1 3.5e-11 43.0 0.0 2.5 1 1 1 2 2 2 2 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 KEZ40304.1 - 2.1e-09 37.4 0.1 4.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KEZ40304.1 - 5.7e-08 32.7 0.0 1.8e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ40304.1 - 0.00027 21.3 0.4 0.0027 18.2 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D2 PF03144.20 KEZ40304.1 - 0.0054 16.8 2.1 0.008 16.2 0.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 SRPRB PF09439.5 KEZ40304.1 - 0.0072 15.5 0.0 0.83 8.8 0.0 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KEZ40304.1 - 0.044 13.0 0.2 0.87 8.8 0.1 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 KEZ40304.1 - 0.044 13.3 0.3 1.4 8.5 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain G-alpha PF00503.15 KEZ40304.1 - 0.063 11.9 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.18 KEZ40304.1 - 0.077 12.8 0.1 3.6 7.3 0.0 2.7 1 1 1 2 2 2 0 Dynamin family Septin PF00735.13 KEZ40304.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Septin Cpn60_TCP1 PF00118.19 KEZ40305.1 - 3.9e-148 494.0 1.6 4.8e-148 493.7 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 KEZ40305.1 - 0.12 12.3 1.2 34 4.3 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain NotI PF12183.3 KEZ40305.1 - 0.18 10.8 0.9 3.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Restriction endonuclease NotI Pkinase PF00069.20 KEZ40307.1 - 2e-13 50.1 0.0 3.7e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40307.1 - 0.0069 15.4 0.1 0.018 14.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3295 PF11702.3 KEZ40308.1 - 7.3e-109 365.0 37.1 2.3e-107 360.0 25.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KEZ40308.1 - 0.00026 20.5 1.8 0.00058 19.3 1.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CENP-B_dimeris PF09026.5 KEZ40308.1 - 0.31 11.3 7.7 0.71 10.1 5.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FGGY_C PF02782.11 KEZ40309.1 - 2.9e-72 242.4 2.8 5.1e-72 241.6 2.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEZ40309.1 - 1.5e-60 204.5 0.0 2e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NTP_transferase PF00483.18 KEZ40310.1 - 7.2e-48 163.0 0.0 1.8e-47 161.7 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KEZ40310.1 - 1.5e-15 55.8 14.6 5e-09 35.2 1.7 3.8 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KEZ40310.1 - 1.4e-11 44.7 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KEZ40310.1 - 2.6e-07 30.0 6.5 5.6e-06 25.8 1.2 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Prenyltrans PF00432.16 KEZ40311.1 - 1.8e-26 91.3 23.9 3.7e-10 39.1 0.4 5.2 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEZ40311.1 - 2e-18 66.8 0.0 7e-17 61.8 0.0 2.7 1 1 0 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEZ40311.1 - 7.8e-05 22.6 0.0 0.00047 20.1 0.0 2.0 2 0 0 2 2 2 1 Prenyltransferase-like Zn_clus PF00172.13 KEZ40312.1 - 0.0031 17.3 7.7 0.0066 16.3 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.18 KEZ40313.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 KEZ40313.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEZ40313.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KEZ40313.1 - 5.2e-22 78.2 1.4 0.00079 19.1 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KEZ40313.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEZ40313.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KEZ40313.1 - 1e-10 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 KEZ40313.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 KEZ40313.1 - 5.4e-06 25.6 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 KEZ40313.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 KEZ40313.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 KEZ40313.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 KEZ40313.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 KEZ40313.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 KEZ40313.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 KEZ40313.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 KEZ40313.1 - 0.038 13.9 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 KEZ40313.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 KEZ40313.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 KEZ40313.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 KEZ40313.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Ank_2 PF12796.2 KEZ40314.1 - 7.9e-78 256.8 0.5 2.1e-15 56.8 0.0 9.3 5 2 2 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ40314.1 - 3.8e-61 199.9 33.8 4.6e-10 38.7 0.1 17.4 18 0 0 18 18 18 9 Ankyrin repeat Ank_4 PF13637.1 KEZ40314.1 - 3.2e-55 183.5 13.7 2.8e-10 40.4 0.0 13.6 11 4 4 15 15 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40314.1 - 9e-50 161.6 23.1 9.2e-07 28.5 0.0 16.8 18 0 0 18 18 17 8 Ankyrin repeat Ank_5 PF13857.1 KEZ40314.1 - 7.2e-49 162.7 25.5 3.7e-09 36.5 0.5 12.7 9 5 3 13 13 12 8 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ40314.1 - 6.9e-09 35.5 0.0 2.1e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 KEZ40314.1 - 8.6e-07 28.0 0.0 1.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KEZ40314.1 - 3.5e-06 27.1 0.0 2e-05 24.6 0.0 2.3 3 0 0 3 3 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ40314.1 - 3.5e-05 23.9 0.1 0.00024 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEZ40314.1 - 0.00039 20.3 0.0 0.0027 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KEZ40314.1 - 0.00063 19.8 0.0 0.0033 17.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 KEZ40314.1 - 0.00096 18.9 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 KEZ40314.1 - 0.018 14.4 0.0 0.068 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 KEZ40314.1 - 0.051 13.3 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 KEZ40314.1 - 0.1 13.3 0.0 1.1 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KEZ40314.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KEZ40314.1 - 0.28 10.1 0.0 0.51 9.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 KEZ40314.1 - 0.32 10.5 0.0 0.91 9.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain zf-UBP PF02148.14 KEZ40315.1 - 7.1e-17 61.2 2.2 1.9e-16 59.9 1.5 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 KEZ40315.1 - 4.9e-13 48.6 0.0 1.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 Acyltransferase PF01553.16 KEZ40316.1 - 2.4e-11 43.2 0.0 1.4e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Sugar_tr PF00083.19 KEZ40318.1 - 1.8e-18 66.3 16.8 9.5e-11 40.9 8.2 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ40318.1 - 3.8e-08 32.4 16.1 1.3e-05 24.1 0.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Phage_tail_T PF06223.7 KEZ40318.1 - 0.15 12.4 0.4 0.7 10.3 0.0 2.2 2 0 0 2 2 2 0 Minor tail protein T Suc_Fer-like PF06999.7 KEZ40319.1 - 9e-34 117.4 0.0 2.8e-33 115.8 0.0 1.8 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer4_13 PF13370.1 KEZ40319.1 - 0.064 13.6 0.7 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain adh_short PF00106.20 KEZ40320.1 - 0.13 12.1 0.0 3 7.7 0.0 2.8 3 0 0 3 3 3 0 short chain dehydrogenase MFS_1 PF07690.11 KEZ40321.1 - 9.6e-21 73.8 33.9 1.2e-20 73.5 22.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ40321.1 - 0.02 14.6 0.7 0.06 13.1 0.5 1.9 1 0 0 1 1 1 0 MFS_1 like family UCR_hinge PF02320.11 KEZ40322.1 - 9.5e-26 89.5 6.4 9.5e-26 89.5 4.4 1.5 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein RRN3 PF05327.6 KEZ40322.1 - 0.074 11.1 5.6 0.085 10.9 3.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Merozoite_SPAM PF07133.6 KEZ40322.1 - 0.18 11.7 16.0 0.2 11.5 11.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) YqfQ PF14181.1 KEZ40322.1 - 0.22 11.5 4.3 0.25 11.3 3.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein BSP_II PF05432.6 KEZ40322.1 - 0.28 10.4 14.3 0.3 10.3 9.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Daxx PF03344.10 KEZ40322.1 - 0.4 9.1 18.6 0.41 9.0 12.9 1.0 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 KEZ40322.1 - 0.44 9.9 9.2 0.48 9.8 6.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.11 KEZ40322.1 - 0.79 8.6 13.8 0.88 8.5 9.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF740 PF05340.7 KEZ40322.1 - 0.92 7.7 9.3 1.1 7.5 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF2722 PF10846.3 KEZ40322.1 - 1.2 8.0 5.0 1.3 7.9 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TLP-20 PF06088.6 KEZ40322.1 - 1.3 8.7 5.1 1.5 8.4 3.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 KEZ40322.1 - 1.4 8.4 19.3 1.8 8.1 13.4 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 KEZ40322.1 - 1.7 8.1 10.7 1.9 7.9 7.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3530 PF12048.3 KEZ40322.1 - 1.8 7.4 8.1 2.2 7.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FAM176 PF14851.1 KEZ40322.1 - 2.1 8.0 7.1 2.5 7.7 4.9 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 KEZ40322.1 - 2.8 5.8 7.2 2.6 5.9 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 KEZ40322.1 - 3.3 6.1 9.0 3.8 6.0 6.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2890 PF11081.3 KEZ40322.1 - 3.4 7.6 13.9 3.6 7.6 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) VID27 PF08553.5 KEZ40322.1 - 3.5 5.7 11.2 3.5 5.7 7.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF3381 PF11861.3 KEZ40322.1 - 3.7 7.0 11.5 5.3 6.5 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Sporozoite_P67 PF05642.6 KEZ40322.1 - 3.9 5.2 5.6 3.9 5.2 3.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 KEZ40322.1 - 4.1 5.2 15.8 4.3 5.1 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 KEZ40322.1 - 4.1 7.7 9.1 6.3 7.1 6.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 KEZ40322.1 - 5 6.4 12.4 5.4 6.3 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Adeno_terminal PF02459.10 KEZ40322.1 - 5.4 5.0 7.7 5.7 4.9 5.3 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SDA1 PF05285.7 KEZ40322.1 - 5.9 6.0 14.7 5.9 6.0 10.2 1.1 1 0 0 1 1 1 0 SDA1 Pox_RNA_Pol_19 PF05320.7 KEZ40322.1 - 7.9 6.1 8.9 9.7 5.9 6.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ycf1 PF05758.7 KEZ40322.1 - 8.3 3.9 6.0 7.9 4.0 4.1 1.0 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 KEZ40322.1 - 8.8 4.9 12.7 9 4.9 8.8 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 KEZ40322.1 - 8.8 6.1 12.0 9.7 5.9 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WWbp PF10349.4 KEZ40323.1 - 2.5e-15 57.3 0.3 3.9e-15 56.7 0.2 1.3 1 0 0 1 1 1 1 WW-domain ligand protein Methyltransf_6 PF03737.10 KEZ40324.1 - 5.1e-19 68.6 0.1 7.1e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Drf_GBD PF06371.8 KEZ40325.1 - 9.9e-14 51.1 2.6 3.3e-12 46.1 1.8 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF192 PF02643.10 KEZ40325.1 - 0.049 13.3 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1430 Pkinase PF00069.20 KEZ40326.1 - 3.3e-09 36.2 0.0 5.9e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40326.1 - 0.11 11.5 0.0 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Nucleoplasmin PF03066.10 KEZ40326.1 - 4.1 6.9 9.0 7.1 6.1 6.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin DNA_pol_phi PF04931.8 KEZ40326.1 - 5.8 4.5 13.1 9 3.9 9.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi VirB3 PF05101.8 KEZ40327.1 - 0.031 14.2 0.2 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Pyridox_oxidase PF01243.15 KEZ40328.1 - 5.6e-09 35.9 0.0 3.8e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_9 PF08021.6 KEZ40328.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_1 PF00175.16 KEZ40328.1 - 0.03 14.8 0.0 0.055 14.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Chromo PF00385.19 KEZ40329.1 - 2.2e-13 49.6 0.3 2.2e-13 49.6 0.2 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KEZ40329.1 - 1.1e-12 47.5 0.2 8.9e-11 41.4 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Nucleo_P87 PF07267.6 KEZ40329.1 - 0.27 9.8 4.4 0.51 8.9 3.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Reo_sigmaC PF04582.7 KEZ40330.1 - 0.0067 15.6 0.1 0.0072 15.5 0.1 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein MCPsignal PF00015.16 KEZ40330.1 - 0.015 14.8 0.6 0.017 14.6 0.4 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.4 KEZ40330.1 - 0.078 12.8 0.3 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Daxx PF03344.10 KEZ40331.1 - 0.00079 18.0 30.0 0.0016 17.0 20.8 1.4 1 0 0 1 1 1 1 Daxx Family DUF4557 PF15101.1 KEZ40331.1 - 0.0012 18.7 12.3 0.0012 18.7 8.5 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4557) PAT1 PF09770.4 KEZ40331.1 - 0.19 9.9 59.9 0.32 9.1 23.1 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 KEZ40331.1 - 0.74 7.5 19.7 0.055 11.3 4.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GOLD_2 PF13897.1 KEZ40331.1 - 6.5 6.9 9.7 0.16 12.1 0.7 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking CTP_transf_2 PF01467.21 KEZ40332.1 - 1.8e-07 31.3 0.0 2.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase tRNA-synt_2 PF00152.15 KEZ40333.1 - 7.9e-86 287.8 0.4 1.1e-85 287.3 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEZ40333.1 - 2.4e-11 43.3 0.1 7.9e-11 41.6 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEZ40333.1 - 2.4e-07 30.2 0.0 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KEZ40333.1 - 0.012 15.2 0.1 0.67 9.5 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) COX15-CtaA PF02628.10 KEZ40334.1 - 8.5e-91 303.9 12.8 1.1e-90 303.6 8.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Utp14 PF04615.8 KEZ40335.1 - 1.7e-175 585.2 63.6 1.7e-175 585.2 44.1 2.3 1 1 1 2 2 2 1 Utp14 protein Na_Ca_ex PF01699.19 KEZ40336.1 - 7.7e-48 161.6 27.1 1e-24 86.7 2.6 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Glyco_hydro_81 PF03639.8 KEZ40337.1 - 8.1e-205 681.8 0.1 1.1e-204 681.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Stn1 PF10451.4 KEZ40338.1 - 2.4e-09 36.4 0.1 1.1e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-like PF12869.2 KEZ40338.1 - 0.2 11.1 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like GreA_GreB_N PF03449.10 KEZ40338.1 - 0.59 10.2 2.6 0.3 11.1 0.2 1.7 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal HMGL-like PF00682.14 KEZ40339.1 - 8.4e-72 241.6 0.2 1.7e-71 240.6 0.2 1.5 1 0 0 1 1 1 1 HMGL-like DnaJ PF00226.26 KEZ40340.1 - 1e-22 79.6 0.7 2.6e-22 78.3 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1800 PF08811.6 KEZ40340.1 - 0.041 12.8 0.4 0.086 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) V-ATPase_G PF03179.10 KEZ40340.1 - 8.7 6.6 11.4 0.092 13.0 0.8 2.7 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit GMC_oxred_N PF00732.14 KEZ40341.1 - 6.9e-53 179.7 0.0 8.7e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ40341.1 - 5.7e-32 110.9 0.0 1.1e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ40341.1 - 4.1e-07 29.2 5.6 7.9e-07 28.3 2.9 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ40341.1 - 7e-07 28.4 0.7 9.6e-05 21.3 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 KEZ40341.1 - 1.6e-05 24.8 0.2 0.006 16.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ40341.1 - 0.00029 20.7 0.2 0.0021 18.0 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ40341.1 - 0.0015 18.6 0.3 0.034 14.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ40341.1 - 0.0058 15.1 0.1 0.13 10.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KEZ40341.1 - 0.031 13.3 0.1 0.06 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KEZ40341.1 - 0.038 13.9 0.2 0.098 12.6 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 KEZ40341.1 - 0.048 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEZ40341.1 - 0.11 11.5 0.1 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KEZ40341.1 - 0.11 12.2 0.3 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding MFS_1 PF07690.11 KEZ40342.1 - 5.5e-39 133.8 57.5 2.4e-37 128.4 30.9 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ40342.1 - 7.4e-16 57.4 26.4 1.4e-15 56.5 18.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Piwi PF02171.12 KEZ40343.1 - 2.7e-74 249.8 0.0 3.7e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KEZ40343.1 - 1.3e-10 40.7 0.0 2.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KEZ40343.1 - 2.6e-08 33.1 0.0 1e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) A_deaminase PF00962.17 KEZ40344.1 - 1.9e-45 155.1 0.0 3e-44 151.3 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KEZ40344.1 - 0.033 14.2 0.5 0.33 11.0 0.4 2.5 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal zf-C3HC PF07967.8 KEZ40346.1 - 3.5e-38 130.3 0.2 1.7e-33 115.2 0.1 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KEZ40346.1 - 7.3e-26 89.8 1.2 1.7e-24 85.5 0.0 2.5 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 KEZ40346.1 - 6.9e-05 23.1 0.1 0.0013 19.1 0.0 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain HET PF06985.6 KEZ40348.1 - 2.8e-18 66.4 0.2 4.5e-16 59.2 0.0 3.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) VHS PF00790.14 KEZ40349.1 - 1.5e-23 83.0 0.0 6.8e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KEZ40349.1 - 2.5e-10 40.2 1.6 5.6e-10 39.0 1.1 1.6 1 0 0 1 1 1 1 GAT domain zf-H2C2_2 PF13465.1 KEZ40350.1 - 2.6e-22 77.9 26.1 3.4e-07 30.2 1.0 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ40350.1 - 7.1e-22 76.3 27.7 1.5e-05 25.0 0.1 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ40350.1 - 4.7e-17 60.9 23.1 7e-05 22.8 1.5 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ40350.1 - 9.1e-08 32.0 8.3 0.32 11.1 0.1 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEZ40350.1 - 2e-05 24.3 13.1 0.012 15.4 0.4 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KEZ40350.1 - 0.00017 21.1 7.6 0.031 13.9 0.3 3.8 5 0 0 5 5 4 2 zinc-finger of a C2HC-type zf-met PF12874.2 KEZ40350.1 - 0.00056 20.0 14.1 1.7 8.9 0.0 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type DUF2072 PF09845.4 KEZ40350.1 - 0.041 13.8 0.1 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) XPA_N PF01286.13 KEZ40350.1 - 0.43 10.2 5.0 2.9 7.6 0.1 3.3 4 0 0 4 4 4 0 XPA protein N-terminal zf-TRAF PF02176.13 KEZ40350.1 - 0.62 10.4 10.0 13 6.2 0.8 3.3 2 1 2 4 4 4 0 TRAF-type zinc finger HNH PF01844.18 KEZ40350.1 - 0.96 9.3 5.4 11 5.9 0.1 3.3 3 0 0 3 3 3 0 HNH endonuclease ADK_lid PF05191.9 KEZ40350.1 - 1 9.0 5.6 34 4.1 0.1 3.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 KEZ40350.1 - 1.5 8.8 11.3 30 4.6 0.1 4.0 2 1 2 4 4 4 0 Zinc ribbon domain Cyt-b5 PF00173.23 KEZ40351.1 - 8.9e-25 86.2 0.1 1.1e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-actin_cap_A PF01267.12 KEZ40352.1 - 6.3e-93 310.7 0.0 7.1e-93 310.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit CSTF2_hinge PF14327.1 KEZ40352.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 Citrate_synt PF00285.16 KEZ40352.1 - 0.15 10.7 0.1 0.22 10.2 0.1 1.1 1 0 0 1 1 1 0 Citrate synthase DUF2461 PF09365.5 KEZ40353.1 - 2.7e-52 177.2 4.5 1.4e-27 96.5 1.1 2.3 2 1 1 3 3 3 2 Conserved hypothetical protein (DUF2461) Daxx PF03344.10 KEZ40353.1 - 8.9 4.6 13.6 11 4.3 9.5 1.1 1 0 0 1 1 1 0 Daxx Family TPR_11 PF13414.1 KEZ40354.1 - 1.1e-34 117.8 9.0 1.7e-11 43.5 0.2 7.4 5 1 2 7 7 7 5 TPR repeat TPR_1 PF00515.23 KEZ40354.1 - 6.5e-30 101.5 0.4 4.6e-05 22.8 0.0 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ40354.1 - 2.4e-27 92.6 16.5 0.00045 19.9 0.1 10.7 12 1 0 12 12 11 6 Tetratricopeptide repeat Apc3 PF12895.2 KEZ40354.1 - 1.7e-25 88.9 9.0 1.2e-15 57.3 0.1 4.8 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEZ40354.1 - 2.1e-21 75.6 14.4 3e-06 27.0 0.3 6.8 4 1 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ40354.1 - 1.6e-18 66.8 26.4 3.8e-09 36.9 0.3 7.6 4 3 5 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ40354.1 - 1.2e-16 59.7 23.2 6e-05 23.3 0.0 10.1 6 2 5 11 11 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ40354.1 - 3.5e-16 59.2 6.8 1.3e-06 28.6 0.1 8.1 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ40354.1 - 1.8e-14 52.3 0.0 0.026 14.3 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ40354.1 - 5.1e-12 44.9 0.7 0.015 15.4 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ40354.1 - 1.4e-10 40.1 3.6 0.048 13.4 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ40354.1 - 5e-09 35.6 3.7 2e-05 23.7 0.9 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ40354.1 - 1.8e-07 30.9 11.6 0.061 13.1 0.2 6.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ40354.1 - 3.2e-07 30.3 12.7 0.51 10.9 0.0 7.9 9 0 0 9 9 7 2 Tetratricopeptide repeat SNAP PF14938.1 KEZ40354.1 - 0.0023 17.1 3.2 0.5 9.4 0.0 2.8 3 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP FAT PF02259.18 KEZ40354.1 - 0.007 15.3 0.3 0.68 8.8 0.2 2.6 1 1 1 2 2 2 2 FAT domain TPR_21 PF09976.4 KEZ40354.1 - 0.01 15.7 5.0 0.032 14.1 0.0 4.0 4 2 1 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.17 KEZ40354.1 - 0.013 14.8 0.1 1.4 8.3 0.0 3.3 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.1 KEZ40354.1 - 0.018 14.9 6.4 23 4.9 0.0 6.0 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 KEZ40354.1 - 0.1 12.4 0.4 2.2 8.0 0.0 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TarH PF02203.10 KEZ40354.1 - 0.14 12.0 2.3 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue TPR_10 PF13374.1 KEZ40354.1 - 0.38 10.7 7.8 14 5.8 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.12 KEZ40354.1 - 4.7 7.5 14.5 1.1 9.5 0.5 4.6 3 1 2 5 5 5 0 Bacterial transcriptional activator domain PTCB-BRCT PF12738.2 KEZ40355.1 - 6.4e-29 99.6 0.5 1.1e-18 66.8 0.1 4.5 5 0 0 5 5 5 3 twin BRCT domain BRCT PF00533.21 KEZ40355.1 - 6.7e-25 87.0 0.0 1.5e-09 37.8 0.0 6.4 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain Lactonase PF10282.4 KEZ40355.1 - 4.6e-13 48.9 0.0 7.5e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ESCRT-II PF05871.7 KEZ40356.1 - 5.1e-47 159.2 0.1 8.5e-47 158.5 0.1 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit HLH PF00010.21 KEZ40357.1 - 9.3e-18 63.6 0.8 1.7e-17 62.8 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC155 PF14662.1 KEZ40357.1 - 0.058 12.9 1.5 0.11 12.0 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 UvrD_C PF13361.1 KEZ40358.1 - 1.3e-74 251.8 0.0 2e-74 251.2 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KEZ40358.1 - 3e-59 200.8 0.1 8.7e-57 192.7 0.0 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KEZ40358.1 - 1.9e-13 50.4 0.0 5.3e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KEZ40358.1 - 3.3e-10 39.5 0.9 1.7e-09 37.2 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KEZ40358.1 - 1e-05 25.1 1.0 0.41 10.1 0.0 3.5 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KEZ40358.1 - 2.7e-05 23.8 0.2 0.00083 18.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KEZ40358.1 - 0.0018 17.6 0.0 0.0062 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Ceramidase_alk PF04734.8 KEZ40359.1 - 3.5e-268 891.0 0.0 4e-268 890.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase zf-RING_4 PF14570.1 KEZ40361.1 - 4.8e-19 67.6 12.0 7.9e-19 66.9 8.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KEZ40361.1 - 1.1e-08 34.5 0.0 4.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ40361.1 - 5.1e-06 26.3 0.0 1.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KEZ40361.1 - 5.3e-06 26.0 6.9 8.6e-06 25.3 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 KEZ40361.1 - 3.1e-05 23.7 0.0 7.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KEZ40361.1 - 3.2e-05 23.2 2.6 3.2e-05 23.2 1.8 3.7 3 1 0 3 3 1 1 Rtf2 RING-finger SET_assoc PF11767.3 KEZ40361.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.1 KEZ40361.1 - 0.057 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.6 KEZ40361.1 - 0.06 13.0 4.8 0.11 12.2 3.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.16 KEZ40361.1 - 0.071 13.0 4.3 0.16 11.8 3.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger DUF576 PF04507.7 KEZ40361.1 - 0.098 11.5 0.9 0.17 10.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF576 zf-UDP PF14569.1 KEZ40361.1 - 0.14 11.9 3.9 0.35 10.6 2.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 KEZ40361.1 - 0.32 10.7 10.2 0.54 10.0 7.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 KEZ40361.1 - 0.41 10.3 10.2 0.79 9.4 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ40361.1 - 1.4 9.0 10.8 2.5 8.1 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.14 KEZ40362.1 - 3e-36 123.7 0.0 4.3e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HECT PF00632.20 KEZ40363.1 - 1.6e-80 270.6 0.0 1.3e-79 267.6 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 KEZ40363.1 - 6.6e-05 22.5 4.3 1.7 8.6 0.0 6.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KEZ40363.1 - 0.0096 15.3 0.1 0.091 12.1 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.1 KEZ40363.1 - 0.021 15.3 0.1 5.9 7.5 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 KEZ40363.1 - 0.16 12.1 6.1 5 7.4 0.0 4.9 6 1 1 7 7 7 0 HEAT repeat E1_dh PF00676.15 KEZ40364.1 - 5.1e-87 291.3 0.0 6.1e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KEZ40364.1 - 0.00045 19.8 0.1 0.0082 15.7 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SGS PF05002.10 KEZ40364.1 - 0.025 14.3 1.0 0.17 11.6 0.2 2.3 2 1 0 2 2 2 0 SGS domain DXP_synthase_N PF13292.1 KEZ40364.1 - 0.042 12.7 0.0 0.13 11.1 0.0 1.7 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase DUF217 PF02697.9 KEZ40364.1 - 0.11 12.7 2.0 0.5 10.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 Ubie_methyltran PF01209.13 KEZ40365.1 - 2.5e-75 252.5 0.0 3e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KEZ40365.1 - 3.1e-15 56.0 0.0 4.6e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40365.1 - 2.4e-14 53.5 0.0 8.4e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ40365.1 - 1.1e-11 45.0 0.0 3e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ40365.1 - 9.8e-11 42.0 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ40365.1 - 3.3e-08 33.5 0.1 6.5e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ40365.1 - 4e-08 33.1 0.0 6.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40365.1 - 1.7e-07 31.8 0.0 3.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KEZ40365.1 - 0.0079 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase OapA_N PF08525.6 KEZ40365.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif DUF2433 PF10360.4 KEZ40366.1 - 1.5e-55 187.0 0.0 2.3e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) DUF2360 PF10152.4 KEZ40366.1 - 9e-05 22.7 11.3 0.0051 17.1 7.8 2.3 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos PF00149.23 KEZ40366.1 - 0.00017 21.0 0.0 0.00039 19.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEZ40366.1 - 0.0058 16.4 0.0 0.016 15.0 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PAT1 PF09770.4 KEZ40366.1 - 9.5 4.3 17.5 14 3.7 12.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zds_C PF08632.5 KEZ40367.1 - 7.8e-29 98.8 0.8 7.8e-29 98.8 0.6 2.0 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zn_clus PF00172.13 KEZ40369.1 - 1.7e-07 31.0 8.2 4.3e-07 29.7 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homez PF11569.3 KEZ40369.1 - 0.11 11.5 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Lipase_GDSL_2 PF13472.1 KEZ40370.1 - 2.2e-11 44.2 0.0 4.4e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ40370.1 - 2.2e-09 37.4 0.2 1e-07 32.0 0.2 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2721 PF11026.3 KEZ40372.1 - 3.6 7.2 8.3 0.15 11.6 1.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Fig1 PF12351.3 KEZ40374.1 - 1.8e-36 125.7 8.3 2.1e-36 125.5 5.8 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KEZ40374.1 - 0.00081 19.0 7.5 0.0016 18.0 5.2 1.6 1 1 0 1 1 1 1 SUR7/PalI family Peptidase_C74 PF12387.3 KEZ40374.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Oxidored_q2 PF00420.19 KEZ40374.1 - 0.045 13.3 0.0 0.045 13.3 0.0 2.7 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L UPF0239 PF06783.6 KEZ40374.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) DUF202 PF02656.10 KEZ40374.1 - 1.7 8.9 9.2 13 6.1 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4064 PF13273.1 KEZ40374.1 - 1.9 8.6 13.5 11 6.2 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) EI24 PF07264.6 KEZ40374.1 - 4.4 6.6 14.8 1.1 8.6 5.8 2.0 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.1 KEZ40374.1 - 9.5 5.5 8.1 0.56 9.5 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ank_2 PF12796.2 KEZ40375.1 - 9.6e-41 138.0 0.5 5.4e-19 68.3 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ40375.1 - 6e-39 129.9 3.0 1.7e-07 30.6 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 KEZ40375.1 - 2.4e-29 101.1 0.4 2.1e-11 44.0 0.1 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40375.1 - 1.8e-28 95.7 0.8 5.4e-07 29.2 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KEZ40375.1 - 3e-24 84.5 1.1 2.5e-08 33.8 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.13 KEZ40375.1 - 5.5e-11 42.0 1.6 1.1e-10 41.0 1.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_T7_Capsid PF05396.6 KEZ40375.1 - 0.047 13.8 0.5 1.6 8.8 0.0 3.4 3 1 1 4 4 4 0 Phage T7 capsid assembly protein PPR_3 PF13812.1 KEZ40375.1 - 0.091 13.0 0.0 34 5.0 0.1 3.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain EMP70 PF02990.11 KEZ40375.1 - 0.32 9.4 1.3 0.51 8.7 0.9 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 KGG PF10685.4 KEZ40376.1 - 2.1e-23 81.7 12.0 9e-13 47.8 1.7 3.4 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif CFEM PF05730.6 KEZ40377.1 - 1.7e-05 24.5 9.0 2.2e-05 24.1 6.2 1.3 1 0 0 1 1 1 1 CFEM domain Metallothio_Euk PF12749.2 KEZ40377.1 - 0.35 10.9 6.1 0.55 10.3 4.3 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein adh_short PF00106.20 KEZ40378.1 - 2.4e-27 95.8 0.0 3.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ40378.1 - 4.5e-24 85.5 0.0 5.5e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ40378.1 - 1.2e-08 34.8 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ40378.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2974 PF11187.3 KEZ40378.1 - 0.036 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Eno-Rase_NADH_b PF12242.3 KEZ40378.1 - 0.1 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KEZ40378.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RCC1 PF00415.13 KEZ40379.1 - 4.3e-57 190.1 23.3 1.7e-08 34.4 0.0 8.5 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEZ40379.1 - 2.4e-31 106.6 34.9 1.1e-06 28.0 0.8 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.10 KEZ40379.1 - 0.16 11.8 3.6 1.3 8.9 0.0 3.4 4 0 0 4 4 4 0 Kelch motif IER PF05760.7 KEZ40379.1 - 2 8.2 25.9 3.4 7.5 18.0 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF3129 PF11327.3 KEZ40380.1 - 6.4e-70 234.7 12.0 8.3e-70 234.3 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Methyltransf_23 PF13489.1 KEZ40381.1 - 1e-21 77.3 0.1 1.5e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40381.1 - 1.7e-10 40.6 0.0 1.8e-09 37.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40381.1 - 1.2e-09 38.5 0.0 2.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40381.1 - 2.2e-09 37.9 0.0 3e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ40381.1 - 5.3e-08 33.2 0.0 1.8e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ40381.1 - 5.8e-06 26.6 0.0 3e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KEZ40381.1 - 5.7e-05 22.3 0.0 0.00013 21.1 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KEZ40381.1 - 0.00099 18.2 0.0 0.0026 16.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ40381.1 - 0.011 15.1 0.0 0.053 12.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KEZ40381.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KEZ40381.1 - 0.038 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 KEZ40381.1 - 0.043 13.8 0.0 0.34 10.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ40381.1 - 0.14 11.5 0.0 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PsaM PF07465.8 KEZ40382.1 - 0.11 12.1 0.9 0.42 10.2 0.6 2.0 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Corona_S2 PF01601.11 KEZ40382.1 - 0.33 9.0 1.4 0.5 8.4 1.0 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Asp PF00026.18 KEZ40383.1 - 8.8e-38 130.3 0.4 1.1e-37 129.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ40383.1 - 0.0001 22.2 0.0 0.00084 19.3 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal MFS_1 PF07690.11 KEZ40385.1 - 5.3e-29 101.0 48.9 9.6e-29 100.1 33.9 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40385.1 - 1.9e-12 46.5 3.8 1.9e-12 46.5 2.6 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KEZ40385.1 - 1.1e-08 33.8 17.2 1.2e-08 33.6 3.3 2.3 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF1479 PF07350.7 KEZ40387.1 - 1.4e-116 389.3 0.1 7.1e-95 317.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 KEZ40387.1 - 0.049 13.6 0.1 11 5.9 0.0 2.5 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) AAA_10 PF12846.2 KEZ40388.1 - 2.1e-09 37.2 0.0 4.1e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 KEZ40388.1 - 0.00023 20.6 0.0 0.0056 16.1 0.0 2.5 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 KEZ40388.1 - 0.00044 20.1 0.5 0.17 11.6 0.0 3.0 4 0 0 4 4 4 2 Domain of unknown function DUF87 AAA_22 PF13401.1 KEZ40388.1 - 0.0023 18.0 0.0 0.3 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KEZ40388.1 - 0.0023 17.4 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KEZ40388.1 - 0.0061 16.5 0.4 1.1 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KEZ40388.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.4 KEZ40388.1 - 0.032 12.8 0.0 0.1 11.1 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 KEZ40388.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KEZ40389.1 - 2.3e-05 23.3 0.1 3.7e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2236 PF09995.4 KEZ40392.1 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Peptidase_C65 PF10275.4 KEZ40392.1 - 0.053 12.8 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase C65 Otubain p450 PF00067.17 KEZ40393.1 - 6.2e-48 163.4 0.0 8.1e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 KEZ40394.1 - 3.5e-23 82.7 0.0 2.8e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ40394.1 - 1.1e-11 43.6 0.5 1.4e-10 40.0 0.3 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ40394.1 - 2.6e-09 36.9 0.0 2.3e-08 33.9 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ40394.1 - 2.6e-08 33.1 0.5 4.4e-05 22.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KEZ40394.1 - 1.2e-05 24.4 0.0 0.091 11.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ40394.1 - 0.00019 21.2 0.1 0.04 13.6 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Malic_M PF03949.10 KEZ40394.1 - 0.031 13.8 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 KEZ40394.1 - 0.05 14.0 1.1 0.85 10.0 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ40394.1 - 0.3 9.5 1.6 0.5 8.7 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein adh_short PF00106.20 KEZ40395.1 - 5.1e-19 68.8 0.1 6.4e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ40395.1 - 4.1e-10 39.8 0.0 4.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ40395.1 - 8.7e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEZ40395.1 - 0.0016 18.1 0.3 0.0043 16.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KEZ40395.1 - 0.059 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HAD PF12710.2 KEZ40395.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Abhydrolase_3 PF07859.8 KEZ40396.1 - 2.7e-51 174.1 0.0 3.3e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEZ40396.1 - 7.7e-09 34.7 0.0 1.5e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEZ40396.1 - 2.2e-08 33.9 0.1 3.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ40396.1 - 4.9e-05 23.3 0.2 7.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KEZ40396.1 - 0.00058 18.6 0.0 0.00074 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KEZ40396.1 - 0.0058 16.2 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ40396.1 - 0.055 12.6 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PhoPQ_related PF10142.4 KEZ40396.1 - 0.14 10.6 0.0 0.44 8.9 0.0 1.7 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Ceramidase PF05875.7 KEZ40397.1 - 5.3e-57 192.9 0.5 6.4e-57 192.6 0.4 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 KEZ40397.1 - 0.21 11.3 2.7 0.81 9.5 1.9 2.0 1 0 0 1 1 1 0 Trp-operon Leader Peptide MFS_1 PF07690.11 KEZ40398.1 - 7e-36 123.6 39.7 1e-35 123.0 27.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Metallopep PF12044.3 KEZ40399.1 - 4.7e-132 440.4 0.0 6.2e-132 440.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.1 KEZ40399.1 - 0.044 13.7 0.2 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KEZ40399.1 - 0.12 12.9 0.5 0.33 11.4 0.3 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KEZ40399.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ZZ PF00569.12 KEZ40399.1 - 1.1 8.8 13.4 0.39 10.2 7.1 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type Cellulase PF00150.13 KEZ40400.1 - 4.1e-08 32.7 0.2 1.1e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) FeoB_C PF07664.7 KEZ40400.1 - 0.22 10.9 0.4 0.38 10.2 0.3 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus Serglycin PF04360.7 KEZ40400.1 - 0.96 9.1 9.7 0.25 11.0 4.4 1.7 2 0 0 2 2 2 0 Serglycin Herpes_capsid PF06112.6 KEZ40400.1 - 4.4 7.3 6.9 8.1 6.4 4.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fungal_trans PF04082.13 KEZ40401.1 - 1.6e-20 73.0 0.8 2.6e-20 72.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40401.1 - 0.014 15.2 2.0 0.023 14.5 1.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 KEZ40402.1 - 2.1e-84 281.9 53.3 1.3e-43 148.6 16.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEZ40402.1 - 2e-35 122.0 0.0 2.7e-17 63.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEZ40402.1 - 2.4e-33 113.8 7.8 4.9e-29 100.0 0.0 3.8 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.1 KEZ40402.1 - 2.4e-18 65.9 0.0 9.2e-18 64.1 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEZ40402.1 - 3.3e-06 26.6 0.0 0.0027 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KEZ40402.1 - 9.8e-06 24.8 44.1 0.00035 19.7 11.2 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 KEZ40402.1 - 2.7e-05 23.3 0.0 0.0009 18.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEZ40402.1 - 3.7e-05 23.1 0.3 0.006 16.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ40402.1 - 4.2e-05 23.6 0.1 0.026 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KEZ40402.1 - 0.00011 21.9 0.5 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 KEZ40402.1 - 0.00014 21.7 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEZ40402.1 - 0.00038 19.9 1.4 0.0048 16.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KEZ40402.1 - 0.00078 20.2 0.0 0.019 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KEZ40402.1 - 0.0031 17.5 0.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KEZ40402.1 - 0.0034 16.6 0.0 0.14 11.3 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 KEZ40402.1 - 0.0065 16.7 0.0 0.11 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEZ40402.1 - 0.0073 16.4 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEZ40402.1 - 0.019 14.6 3.0 1.5 8.4 0.1 3.1 4 0 0 4 4 3 0 NACHT domain PDR_assoc PF08370.6 KEZ40402.1 - 0.022 14.2 11.0 1.4 8.4 0.4 4.0 3 0 0 3 3 3 0 Plant PDR ABC transporter associated AAA_30 PF13604.1 KEZ40402.1 - 0.04 13.5 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEZ40402.1 - 0.16 11.6 0.0 20 4.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 KEZ40402.1 - 0.22 10.9 0.2 8.4 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 KEZ40402.1 - 0.25 11.8 0.0 32 5.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 KEZ40402.1 - 0.27 10.8 0.9 0.94 9.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KEZ40402.1 - 0.28 11.1 0.0 24 4.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase p450 PF00067.17 KEZ40403.1 - 3.1e-38 131.4 0.0 3.8e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PGAP1 PF07819.8 KEZ40404.1 - 0.14 11.6 0.2 0.35 10.4 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein APH PF01636.18 KEZ40405.1 - 1.4e-20 74.0 0.0 1e-09 38.5 0.0 2.8 2 0 0 2 2 2 2 Phosphotransferase enzyme family Epimerase PF01370.16 KEZ40405.1 - 2.3e-19 69.7 0.0 3.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEZ40405.1 - 3.6e-13 48.8 0.0 5.4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KEZ40405.1 - 3.8e-11 42.3 0.0 7.3e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KEZ40405.1 - 1.6e-08 34.7 0.1 3.2e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEZ40405.1 - 4.7e-08 33.1 0.0 1.2e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ40405.1 - 0.00036 20.2 0.0 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Alpha-L-AF_C PF06964.7 KEZ40406.1 - 6.3e-24 84.7 0.0 9.7e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Gtr1_RagA PF04670.7 KEZ40407.1 - 3.4e-92 307.7 0.0 4.3e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KEZ40407.1 - 2.4e-07 30.2 0.0 6e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.16 KEZ40407.1 - 5.4e-06 25.7 0.0 8.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEZ40407.1 - 4.2e-05 23.4 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ40407.1 - 0.0002 21.8 0.0 0.00044 20.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KEZ40407.1 - 0.0029 17.1 1.7 0.0088 15.5 0.4 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KEZ40407.1 - 0.004 17.4 0.1 0.009 16.3 0.1 1.6 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.8 KEZ40407.1 - 0.021 13.7 0.1 0.049 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.12 KEZ40407.1 - 0.026 14.3 0.2 0.095 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF258 PF03193.11 KEZ40407.1 - 0.069 12.3 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KEZ40407.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 KEZ40407.1 - 0.11 11.1 0.2 1 7.9 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit SEP PF08059.8 KEZ40408.1 - 4.8e-22 78.0 0.0 8.2e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 KEZ40408.1 - 2.1e-11 43.1 0.2 3.3e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KEZ40408.1 - 3.1e-08 33.5 0.0 5.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 KEZ40408.1 - 7.6e-06 25.6 0.1 1.6e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF1488 PF07369.6 KEZ40408.1 - 0.18 11.6 0.3 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) UPF0560 PF10577.4 KEZ40408.1 - 0.32 9.1 1.8 0.43 8.7 1.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TOM13 PF08219.6 KEZ40409.1 - 1.2e-29 101.8 0.0 1.6e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 KEZ40410.1 - 7.9e-30 103.9 1.6 7.9e-30 103.9 1.1 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein DUF1688 PF07958.6 KEZ40411.1 - 2.3e-168 560.0 0.0 2.7e-168 559.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF3411 PF11891.3 KEZ40412.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3411) PNTB PF02233.11 KEZ40412.1 - 0.27 9.9 2.3 0.18 10.5 0.3 1.5 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit DEAD PF00270.24 KEZ40413.1 - 1.3e-40 138.6 0.2 2.8e-40 137.5 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ40413.1 - 4.3e-29 100.1 0.1 9.2e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 KEZ40413.1 - 0.0073 15.6 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.1 KEZ40413.1 - 0.0095 15.5 0.4 0.022 14.3 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ40413.1 - 0.015 15.0 0.2 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 KEZ40413.1 - 0.035 13.9 0.1 0.07 12.9 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KEZ40413.1 - 0.051 13.3 0.3 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 KEZ40413.1 - 0.096 12.8 0.7 0.43 10.7 0.5 2.0 1 1 0 1 1 1 0 AAA domain PLU-1 PF08429.6 KEZ40414.1 - 1.1e-98 330.3 11.3 2.8e-95 319.0 8.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KEZ40414.1 - 1.4e-42 144.5 0.1 3.5e-42 143.2 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KEZ40414.1 - 4.8e-25 87.2 0.0 1.8e-24 85.4 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KEZ40414.1 - 6.8e-16 57.6 30.7 4.4e-08 32.6 5.3 3.8 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 KEZ40414.1 - 6.9e-16 57.4 1.8 1.5e-15 56.3 1.2 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 KEZ40414.1 - 1.7e-15 56.8 5.8 3.8e-15 55.6 4.0 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.1 KEZ40414.1 - 0.028 13.7 8.3 0.078 12.2 0.9 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.1 KEZ40414.1 - 0.2 11.5 20.1 0.31 10.8 4.7 2.7 2 0 0 2 2 2 0 Ring finger domain PHD_2 PF13831.1 KEZ40414.1 - 3.1 7.1 16.3 0.095 12.0 1.1 3.1 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.17 KEZ40414.1 - 8.6 6.1 27.0 0.044 13.5 2.7 3.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sdh_cyt PF01127.17 KEZ40415.1 - 8.4e-20 70.8 4.1 1.1e-19 70.4 2.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 KEZ40416.1 - 1e-22 80.0 0.0 1.9e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KEZ40416.1 - 9e-21 73.5 0.2 2e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 KEZ40416.1 - 0.00019 21.4 0.2 0.00035 20.6 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEZ40416.1 - 0.063 13.3 0.1 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DJ-1_PfpI PF01965.19 KEZ40417.1 - 7.8e-28 96.7 0.0 1.7e-27 95.7 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KEZ40417.1 - 1.1e-12 47.2 0.1 1.9e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 KEZ40417.1 - 0.0091 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 KEZ40417.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I GATase_3 PF07685.9 KEZ40417.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SRP54 PF00448.17 KEZ40418.1 - 1.7e-77 259.3 2.6 3.4e-77 258.3 0.9 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KEZ40418.1 - 1.3e-25 89.6 4.6 1.3e-25 89.6 3.2 4.2 3 1 3 6 6 4 1 Signal peptide binding domain SRP54_N PF02881.14 KEZ40418.1 - 2.8e-14 52.9 0.3 6.1e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KEZ40418.1 - 4.3e-08 32.8 0.1 1.1e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KEZ40418.1 - 2e-07 30.9 0.1 5.6e-07 29.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 KEZ40418.1 - 1.5e-06 27.9 0.0 4.2e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KEZ40418.1 - 2.4e-05 23.8 0.2 8.7e-05 22.0 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KEZ40418.1 - 6.4e-05 23.7 0.0 0.00014 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KEZ40418.1 - 0.00016 21.6 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KEZ40418.1 - 0.00061 19.4 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.12 KEZ40418.1 - 0.00076 18.9 0.4 0.0032 16.8 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase SRPRB PF09439.5 KEZ40418.1 - 0.00091 18.4 0.8 2 7.5 0.1 3.3 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit 6PF2K PF01591.13 KEZ40418.1 - 0.0019 17.3 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_22 PF13401.1 KEZ40418.1 - 0.002 18.2 0.1 0.0082 16.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KEZ40418.1 - 0.003 17.5 0.1 0.0084 16.1 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain ArgK PF03308.11 KEZ40418.1 - 0.0043 15.8 0.7 0.0043 15.8 0.5 2.6 2 1 0 2 2 2 1 ArgK protein Zeta_toxin PF06414.7 KEZ40418.1 - 0.0069 15.5 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.12 KEZ40418.1 - 0.012 15.1 0.5 0.035 13.6 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KEZ40418.1 - 0.019 14.9 0.1 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KEZ40418.1 - 0.02 14.8 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KEZ40418.1 - 0.025 14.9 0.1 0.074 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ40418.1 - 0.026 14.2 0.0 0.11 12.2 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain TrwB_AAD_bind PF10412.4 KEZ40418.1 - 0.026 13.1 0.6 0.067 11.7 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 KEZ40418.1 - 0.045 13.1 0.1 0.091 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain VirE PF05272.6 KEZ40418.1 - 0.061 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA PF00004.24 KEZ40418.1 - 0.083 13.0 0.2 0.4 10.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KEZ40418.1 - 0.14 11.9 0.4 0.79 9.5 0.1 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SGL PF08450.7 KEZ40419.1 - 5.4e-05 22.6 0.7 0.00065 19.1 0.0 2.6 3 1 0 3 3 3 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 KEZ40419.1 - 0.0015 17.7 0.1 0.99 8.4 0.0 3.0 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller PD40 PF07676.7 KEZ40419.1 - 0.013 15.1 0.1 0.97 9.1 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat B9-C2 PF07162.6 KEZ40419.1 - 0.032 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein His_Phos_2 PF00328.17 KEZ40420.1 - 1e-05 25.0 0.0 0.00015 21.2 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HCV_NS5a_1b PF08301.8 KEZ40420.1 - 0.091 13.1 0.2 4.2 7.7 0.1 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b MFS_1 PF07690.11 KEZ40422.1 - 2.5e-36 125.1 25.1 2.5e-36 125.1 17.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ40423.1 - 3e-22 78.7 0.2 7.3e-22 77.4 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KEZ40424.1 - 1.9e-51 175.0 0.0 3e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KEZ40424.1 - 1.6e-07 30.7 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40424.1 - 0.0024 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEZ40424.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEZ40424.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TFIIA_gamma_N PF02268.11 KEZ40424.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain FAD_binding_4 PF01565.18 KEZ40425.1 - 1.5e-20 73.1 0.8 2.5e-20 72.3 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ40425.1 - 3.2e-07 30.1 0.2 7.2e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KEZ40425.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.6 KEZ40426.1 - 9.7e-18 64.6 0.0 1.7e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 KEZ40428.1 - 1.4e-46 158.4 0.0 2.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEZ40428.1 - 7.2e-08 32.3 6.0 0.0017 18.5 0.9 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ40428.1 - 0.00069 19.7 1.2 0.00069 19.7 0.8 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger PAT1 PF09770.4 KEZ40428.1 - 0.0014 16.9 38.4 0.002 16.5 26.6 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 zf-H2C2_2 PF13465.1 KEZ40428.1 - 0.017 15.4 0.6 0.017 15.4 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Ank_2 PF12796.2 KEZ40429.1 - 1.1e-21 76.9 2.9 2.2e-13 50.3 0.2 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ40429.1 - 3.9e-19 68.6 0.3 1.1e-09 38.4 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KEZ40429.1 - 4.4e-16 57.8 1.6 2e-06 27.3 0.2 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KEZ40429.1 - 3.9e-12 45.1 0.3 0.00078 19.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KEZ40429.1 - 4.8e-12 45.7 2.6 2.7e-06 27.4 0.5 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Prenyltrans PF00432.16 KEZ40430.1 - 1.4e-27 94.9 15.5 2.3e-10 39.8 0.2 6.0 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KEZ40430.1 - 2.6e-26 91.7 0.2 7.8e-12 45.1 0.1 6.1 4 2 2 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 KEZ40430.1 - 7.3e-26 90.7 1.8 1.2e-16 61.0 0.1 4.8 4 2 1 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 KEZ40430.1 - 2.2e-06 27.0 0.9 0.14 11.2 0.0 4.7 4 1 1 5 5 5 2 Pectic acid lyase Chromadorea_ALT PF05535.7 KEZ40430.1 - 0.0011 18.9 0.1 0.003 17.6 0.1 1.7 1 0 0 1 1 1 1 Chromadorea ALT protein A2M_comp PF07678.9 KEZ40430.1 - 0.013 14.7 0.1 2.1 7.5 0.0 3.3 2 1 1 4 4 4 0 A-macroglobulin complement component Mago-bind PF09282.5 KEZ40430.1 - 0.074 12.6 0.0 2.4 7.7 0.0 2.7 2 0 0 2 2 2 0 Mago binding TauD PF02668.11 KEZ40431.1 - 3.2e-46 158.0 0.1 5.2e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SGS PF05002.10 KEZ40431.1 - 4.8e-27 93.5 2.5 9.7e-27 92.5 1.7 1.5 1 0 0 1 1 1 1 SGS domain TPR_11 PF13414.1 KEZ40431.1 - 3.5e-07 29.7 0.0 1.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEZ40431.1 - 0.039 13.8 0.2 0.67 10.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CS PF04969.11 KEZ40431.1 - 0.054 14.0 0.1 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 CS domain CsiD PF08943.5 KEZ40431.1 - 0.081 11.8 0.0 0.23 10.3 0.0 1.7 1 1 0 1 1 1 0 CsiD Glyco_transf_21 PF13506.1 KEZ40432.1 - 1.3e-12 47.3 0.0 1.6e-05 24.2 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KEZ40432.1 - 2.1e-12 47.3 0.0 5.1e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEZ40432.1 - 5.5e-05 22.9 0.0 0.0075 15.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 MFS_1 PF07690.11 KEZ40433.1 - 1.5e-35 122.5 24.5 1.9e-26 92.6 7.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_3 PF05977.8 KEZ40433.1 - 2.2e-06 26.1 1.9 5.2e-06 24.8 1.4 1.6 1 1 0 1 1 1 1 Transmembrane secretion effector BT1 PF03092.11 KEZ40433.1 - 2e-05 23.5 0.1 0.0093 14.7 0.0 2.7 3 1 0 3 3 3 2 BT1 family OATP PF03137.15 KEZ40433.1 - 0.017 13.1 1.9 0.28 9.1 0.0 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Dioxygenase_C PF00775.16 KEZ40434.1 - 1.6e-08 34.0 0.7 4.3e-08 32.6 0.5 1.7 1 1 0 1 1 1 1 Dioxygenase DUF3328 PF11807.3 KEZ40435.1 - 1.7e-23 83.4 0.1 2e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CBM_1 PF00734.13 KEZ40436.1 - 3.5e-08 32.9 5.4 5.6e-08 32.3 3.7 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF605 PF04652.11 KEZ40436.1 - 2.9 7.2 15.5 3.5 6.9 10.7 1.1 1 0 0 1 1 1 0 Vta1 like AMP-binding PF00501.23 KEZ40437.1 - 1.5e-56 191.6 0.0 2.1e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 KEZ40437.1 - 4.7e-10 38.5 12.5 1.7e-05 24.0 0.1 5.8 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 KEZ40437.1 - 4e-08 33.4 0.0 1.3e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.1 KEZ40437.1 - 3.5e-05 23.2 14.9 0.23 11.0 0.5 6.2 6 1 0 6 6 6 2 Hexapeptide repeat of succinyl-transferase Nop10p PF04135.7 KEZ40438.1 - 5.9e-20 70.7 0.0 7.7e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family YkuD_2 PF13645.1 KEZ40438.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain CRAL_TRIO PF00650.15 KEZ40439.1 - 2.1e-41 141.0 0.0 3.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEZ40439.1 - 1.9e-09 37.4 0.6 3.9e-09 36.5 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEZ40439.1 - 4.2e-05 23.4 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PAD_porph PF04371.10 KEZ40439.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase TRAPP PF04051.11 KEZ40440.1 - 8.2e-38 129.3 0.0 9.7e-38 129.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Apc13p PF05839.6 KEZ40441.1 - 3.1e-35 120.0 0.4 3.5e-35 119.8 0.3 1.0 1 0 0 1 1 1 1 Apc13p protein ABC_tran PF00005.22 KEZ40442.1 - 5.3e-51 172.5 0.0 3e-30 105.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ40442.1 - 8e-45 153.3 27.1 9.9e-25 87.4 5.9 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KEZ40442.1 - 2.9e-08 33.2 2.7 0.0046 16.2 0.2 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEZ40442.1 - 6.3e-08 33.1 3.4 0.00033 21.0 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_29 PF13555.1 KEZ40442.1 - 8.9e-07 28.3 0.1 0.029 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 KEZ40442.1 - 9.7e-06 25.7 0.0 0.24 11.3 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KEZ40442.1 - 5.8e-05 22.6 0.1 0.036 13.5 0.0 2.6 2 1 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KEZ40442.1 - 7.7e-05 22.1 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KEZ40442.1 - 8.6e-05 21.7 0.3 0.38 9.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 KEZ40442.1 - 0.00012 22.2 0.5 3.1 7.9 0.1 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KEZ40442.1 - 0.00015 20.8 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 KEZ40442.1 - 0.00024 21.0 0.0 0.07 13.0 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ40442.1 - 0.00036 19.7 0.0 0.46 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ40442.1 - 0.00041 20.3 0.7 0.74 9.7 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 KEZ40442.1 - 0.0042 16.9 4.9 0.03 14.1 0.0 2.9 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 KEZ40442.1 - 0.0054 17.5 0.0 6.5 7.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEZ40442.1 - 0.0071 15.9 0.5 2.4 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KEZ40442.1 - 0.0099 16.3 0.0 5.5 7.5 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein DUF815 PF05673.8 KEZ40442.1 - 0.01 14.7 0.2 0.43 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 KEZ40442.1 - 0.016 14.6 0.0 5.4 6.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 KEZ40442.1 - 0.017 13.7 0.3 2.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 KEZ40442.1 - 0.019 14.6 0.2 5 6.8 0.0 4.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KEZ40442.1 - 0.025 14.0 0.0 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.18 KEZ40442.1 - 0.028 14.2 0.5 1.9 8.2 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA PF00004.24 KEZ40442.1 - 0.073 13.2 0.2 45 4.2 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEZ40442.1 - 0.11 11.9 0.0 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain SecY PF00344.15 KEZ40443.1 - 6.2e-96 321.3 10.9 8e-96 320.9 7.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KEZ40443.1 - 1.1e-17 63.1 0.4 1.1e-16 60.0 0.2 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p Fungal_trans PF04082.13 KEZ40444.1 - 1.8e-23 82.7 0.1 2.6e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40444.1 - 5.7e-09 35.7 8.6 1e-08 34.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEZ40445.1 - 1.5e-44 152.1 49.8 1e-41 142.8 34.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ40445.1 - 2.8e-15 55.5 23.6 5.6e-15 54.5 16.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 KEZ40446.1 - 3.5e-11 42.7 0.0 5e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40446.1 - 2.2e-07 30.2 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ40446.1 - 0.038 12.9 0.0 0.079 11.9 0.0 1.4 2 0 0 2 2 2 0 Kinase-like NUDIX PF00293.23 KEZ40447.1 - 4.9e-16 58.6 0.1 6.1e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain KH_1 PF00013.24 KEZ40447.1 - 0.1 12.2 0.2 0.99 9.1 0.0 2.2 2 0 0 2 2 2 0 KH domain KH_3 PF13014.1 KEZ40447.1 - 0.13 11.9 1.4 0.23 11.1 0.0 2.1 3 0 0 3 3 3 0 KH domain Y_phosphatase3 PF13350.1 KEZ40448.1 - 1.8e-42 145.3 0.0 2.4e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEZ40448.1 - 9.7e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KEZ40448.1 - 0.0046 16.3 0.0 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KEZ40448.1 - 0.014 15.5 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region DSPc PF00782.15 KEZ40448.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 KEZ40448.1 - 0.18 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Adaptin_binding PF10199.4 KEZ40449.1 - 1.7e-14 54.2 9.3 2.4e-14 53.7 6.5 1.2 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Wbp11 PF09429.5 KEZ40449.1 - 0.055 13.4 4.4 0.13 12.2 3.1 1.6 1 0 0 1 1 1 0 WW domain binding protein 11 Axin_b-cat_bind PF08833.5 KEZ40449.1 - 1.2 8.9 4.8 11 5.7 1.0 2.6 2 0 0 2 2 2 0 Axin beta-catenin binding domain Homeobox PF00046.24 KEZ40450.1 - 7.2e-19 67.1 3.5 1.3e-18 66.2 2.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KEZ40450.1 - 2.8e-05 23.7 0.3 6.7e-05 22.5 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain E1-E2_ATPase PF00122.15 KEZ40451.1 - 8.7e-21 74.0 0.0 2.2e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ40451.1 - 1.3e-14 55.1 0.0 4.3e-10 40.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ40451.1 - 4.1e-14 53.2 0.1 7.4e-13 49.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ40451.1 - 2.8e-10 40.0 0.0 7.6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEZ40451.1 - 0.0035 16.9 0.7 0.0084 15.7 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase TrbC_Ftype PF09673.5 KEZ40451.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein HAD_2 PF13419.1 KEZ40451.1 - 0.029 14.5 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KEZ40451.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HlyIII PF03006.15 KEZ40452.1 - 6.2e-33 114.0 12.7 8.5e-33 113.6 8.8 1.0 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_M50B PF13398.1 KEZ40453.1 - 4.6e-57 192.6 18.4 5.9e-57 192.2 12.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 KEZ40453.1 - 0.0015 17.4 1.9 0.0063 15.4 0.1 2.4 1 1 1 2 2 2 1 Peptidase family M50 Peptidase_M41 PF01434.13 KEZ40453.1 - 0.074 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 TIP120 PF08623.5 KEZ40454.1 - 1.4e-62 210.2 0.3 3.7e-60 202.3 0.0 4.0 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KEZ40454.1 - 5.4e-23 81.0 30.4 0.0023 18.1 0.6 9.1 8 2 2 10 10 9 8 HEAT repeats HEAT PF02985.17 KEZ40454.1 - 2.3e-09 36.5 31.1 0.11 12.5 0.0 11.2 13 0 0 13 13 11 5 HEAT repeat Adaptin_N PF01602.15 KEZ40454.1 - 1.2e-06 27.1 7.3 0.00039 18.8 0.1 6.1 4 3 3 7 7 7 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KEZ40454.1 - 1.1e-05 25.7 0.3 4.1 7.8 0.0 6.0 6 1 1 7 7 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KEZ40454.1 - 9e-05 21.9 5.8 0.03 13.7 0.0 5.0 5 1 1 6 6 6 1 CLASP N terminal HEAT_EZ PF13513.1 KEZ40454.1 - 0.00029 21.2 44.1 6 7.5 0.1 12.9 14 3 4 18 18 15 2 HEAT-like repeat DUF2435 PF10363.4 KEZ40454.1 - 0.0017 18.1 7.3 0.94 9.4 0.0 5.3 6 0 0 6 6 6 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KEZ40454.1 - 0.014 15.2 10.1 2.5 7.8 0.4 5.7 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.3 KEZ40454.1 - 0.12 12.0 2.0 43 3.7 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) MMS19_N PF14500.1 KEZ40454.1 - 0.4 9.8 1.9 11 5.1 0.1 4.0 4 2 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Nop14 PF04147.7 KEZ40454.1 - 1 7.1 7.0 2 6.2 4.8 1.4 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 KEZ40454.1 - 1.9 8.8 12.3 4.4 7.5 8.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain COMPASS-Shg1 PF05205.7 KEZ40455.1 - 9.9e-24 83.6 0.7 2.2e-23 82.5 0.5 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF-2B PF01008.12 KEZ40457.1 - 8e-52 175.9 1.7 3e-51 174.0 1.2 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Glycos_transf_2 PF00535.21 KEZ40457.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_S26 PF10502.4 KEZ40458.1 - 4.7e-05 22.9 0.0 0.0034 16.8 0.0 2.7 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 KEZ40458.1 - 0.00082 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Arm PF00514.18 KEZ40459.1 - 2.1e-69 227.2 32.6 4.9e-12 45.2 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KEZ40459.1 - 5e-22 77.9 15.2 4.3e-07 30.1 0.2 7.4 2 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 KEZ40459.1 - 1.2e-17 62.3 16.1 0.043 13.8 0.1 9.3 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KEZ40459.1 - 4.9e-16 58.6 14.5 0.0049 17.3 0.3 8.3 5 1 4 9 9 9 6 HEAT-like repeat Adaptin_N PF01602.15 KEZ40459.1 - 1.5e-11 43.3 5.5 1.6e-06 26.7 0.1 2.8 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 KEZ40459.1 - 1e-10 41.1 5.9 0.0061 15.7 0.0 3.3 2 1 1 3 3 3 3 Armadillo-like KAP PF05804.7 KEZ40459.1 - 1.5e-07 29.7 0.2 2.4e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KEZ40459.1 - 6.1e-07 28.8 0.3 0.016 14.3 0.6 3.3 2 1 1 3 3 3 2 V-ATPase subunit H DUF2454 PF10521.4 KEZ40459.1 - 0.00013 21.1 0.4 0.017 14.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2454) DUF908 PF06012.7 KEZ40459.1 - 0.00071 18.9 1.5 0.6 9.3 0.1 3.9 4 1 1 5 5 5 1 Domain of Unknown Function (DUF908) HEAT_PBS PF03130.11 KEZ40459.1 - 0.0036 17.6 4.1 98 3.8 0.0 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat RIX1 PF08167.7 KEZ40459.1 - 0.064 12.9 0.4 1.8 8.2 0.1 2.9 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis CBS PF00571.23 KEZ40460.1 - 7.1e-30 102.5 8.4 3.2e-13 49.2 0.4 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.22 KEZ40461.1 - 5.4e-09 35.8 0.0 9.8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Rep_fac-A_3 PF08661.6 KEZ40462.1 - 2.2e-15 56.4 0.0 3.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Replication factor A protein 3 TFIIF_alpha PF05793.7 KEZ40462.1 - 0.0064 14.9 9.3 0.0079 14.6 6.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 KEZ40462.1 - 0.0095 15.0 9.6 0.012 14.6 6.6 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.8 KEZ40462.1 - 0.076 12.8 5.9 0.092 12.6 4.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KEZ40462.1 - 0.2 9.5 16.6 0.25 9.2 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KEZ40462.1 - 0.78 8.1 18.2 1.1 7.6 12.6 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KEZ40462.1 - 1.5 8.0 18.1 2 7.5 12.5 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.7 KEZ40462.1 - 3.2 6.0 19.3 4.5 5.5 13.4 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF605 PF04652.11 KEZ40462.1 - 4.3 6.6 15.6 6.3 6.0 10.8 1.3 1 0 0 1 1 1 0 Vta1 like Nucleoplasmin PF03066.10 KEZ40462.1 - 4.4 6.7 22.6 1 8.8 8.9 2.4 2 0 0 2 2 2 0 Nucleoplasmin Prp19_bind PF06991.6 KEZ40462.1 - 6.3 5.9 17.7 12 5.0 12.2 1.3 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Alb1 PF09135.6 KEZ40463.1 - 2.2e-22 79.7 12.2 3.1e-22 79.3 8.4 1.2 1 0 0 1 1 1 1 Alb1 Methyltrans_SAM PF10672.4 KEZ40463.1 - 0.049 12.4 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase F-protein PF00469.15 KEZ40463.1 - 0.093 12.0 2.1 0.12 11.6 1.4 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef bZIP_1 PF00170.16 KEZ40464.1 - 4e-12 45.9 0.2 8.2e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ40464.1 - 6.4e-08 32.2 0.2 1.5e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KEZ40464.1 - 0.00088 19.5 0.5 0.00088 19.5 0.3 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Ribosomal_L4 PF00573.17 KEZ40465.1 - 6e-45 152.9 0.0 9.1e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 KEZ40466.1 - 5.1e-09 36.1 0.0 8.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PLDc_2 PF13091.1 KEZ40467.1 - 4.6e-14 52.2 0.0 3.4e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KEZ40467.1 - 1.5e-07 31.0 0.8 0.027 14.2 0.0 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.11 KEZ40468.1 - 7.9e-24 84.1 0.1 9.4e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PNTB PF02233.11 KEZ40469.1 - 1.7e-125 419.4 33.9 7.3e-84 282.1 0.6 2.8 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KEZ40469.1 - 5.7e-55 185.4 1.2 1.1e-54 184.4 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KEZ40469.1 - 5.7e-48 162.3 1.0 1.9e-47 160.6 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KEZ40469.1 - 2.2e-30 104.6 2.2 2.2e-30 104.6 1.5 4.2 5 0 0 5 5 4 1 Domain of unknown function (DUF3814) ADH_zinc_N PF00107.21 KEZ40469.1 - 0.00033 20.1 0.1 0.0012 18.3 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ40469.1 - 0.005 16.0 0.1 0.77 8.8 0.0 3.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KEZ40469.1 - 0.0063 17.0 0.0 0.019 15.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.9 KEZ40469.1 - 0.0067 16.3 0.5 0.045 13.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.9 KEZ40469.1 - 0.019 14.0 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Methyltransf_31 PF13847.1 KEZ40469.1 - 0.032 13.8 0.0 0.19 11.3 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain FAD_binding_2 PF00890.19 KEZ40469.1 - 0.077 11.8 4.5 0.41 9.4 1.2 2.4 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 KEZ40469.1 - 3.6 7.6 7.6 0.3 11.1 0.9 2.7 3 1 0 3 3 1 0 NAD(P)-binding Rossmann-like domain Thymidylate_kin PF02223.12 KEZ40470.1 - 8.8e-45 152.3 0.0 1.3e-42 145.2 0.0 2.0 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.1 KEZ40470.1 - 6e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEZ40470.1 - 3.9e-05 22.9 0.0 8.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 KEZ40470.1 - 0.0071 15.9 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KEZ40470.1 - 0.14 12.4 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SAGA-Tad1 PF12767.2 KEZ40471.1 - 0.48 10.0 25.2 0.93 9.1 17.5 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.2 KEZ40471.1 - 3 5.4 18.5 3.8 5.0 12.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lipase_GDSL PF00657.17 KEZ40472.1 - 1.2e-16 61.2 0.1 1.7e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ40472.1 - 1.1e-06 28.9 1.4 4.6e-06 26.8 1.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_76 PF03663.9 KEZ40473.1 - 6.7e-94 315.2 4.6 8.5e-94 314.9 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KEZ40473.1 - 0.035 13.1 0.7 1.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.16 KEZ40474.1 - 1.4e-66 224.8 0.0 1.7e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEZ40474.1 - 0.0018 16.6 0.0 0.0051 15.1 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 KEZ40474.1 - 0.0099 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 1 Allinase Acyl_transf_3 PF01757.17 KEZ40476.1 - 1.1e-26 93.4 33.6 4e-26 91.6 23.3 1.8 1 1 0 1 1 1 1 Acyltransferase family Tachykinin PF02202.11 KEZ40476.1 - 0.14 11.8 1.2 0.65 9.8 0.8 2.2 1 0 0 1 1 1 0 Tachykinin family Transport_MerF PF11431.3 KEZ40476.1 - 2.3 7.9 6.2 3.7 7.2 0.1 3.1 3 0 0 3 3 3 0 Membrane transport protein MerF AAA_25 PF13481.1 KEZ40477.1 - 4.6e-08 32.7 0.1 2.7e-07 30.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 KEZ40477.1 - 8.3e-05 21.8 0.0 0.00022 20.4 0.0 1.6 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.12 KEZ40477.1 - 0.00011 21.7 0.0 0.00051 19.5 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein RecA PF00154.16 KEZ40477.1 - 0.00029 20.0 0.0 0.001 18.2 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 KEZ40477.1 - 0.0012 17.8 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain Rad51 PF08423.6 KEZ40477.1 - 0.0014 17.5 0.0 0.0088 14.9 0.0 2.0 1 1 0 1 1 1 1 Rad51 AAA PF00004.24 KEZ40477.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KEZ40477.1 - 0.021 14.3 0.0 0.37 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ40477.1 - 0.082 12.6 0.1 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 KEZ40477.1 - 0.13 11.6 0.1 0.56 9.5 0.0 1.7 1 1 0 2 2 2 0 AAA-like domain 3HCDH_N PF02737.13 KEZ40477.1 - 0.21 11.2 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-H2C2_2 PF13465.1 KEZ40478.1 - 1.4e-08 34.6 16.7 3.3e-06 27.1 2.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ40478.1 - 2.5e-07 30.6 14.9 0.0022 18.2 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ40478.1 - 9e-05 22.5 14.1 0.005 17.0 0.9 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ40478.1 - 3.4 7.9 5.5 1.5 9.0 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TIM21 PF08294.6 KEZ40479.1 - 1.5e-46 157.6 0.0 1.9e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KEZ40479.1 - 0.0048 16.3 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 KEZ40480.1 - 7.8e-36 122.4 0.1 1.4e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF566 PF04484.7 KEZ40480.1 - 0.19 11.1 3.2 0.28 10.6 2.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) NMO PF03060.10 KEZ40481.1 - 2.9e-71 240.3 1.3 3.8e-71 239.9 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KEZ40481.1 - 9.4e-08 31.3 0.0 4.9e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEZ40481.1 - 1.2e-06 27.5 1.8 2.4e-06 26.6 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KEZ40481.1 - 0.00023 20.2 0.3 0.00046 19.2 0.2 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.9 KEZ40481.1 - 0.012 14.5 0.1 0.027 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.12 KEZ40481.1 - 0.014 14.3 0.2 0.022 13.7 0.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Radial_spoke_3 PF06098.6 KEZ40481.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 Pterin_bind PF00809.17 KEZ40482.1 - 1.3e-63 214.1 0.0 2.9e-63 213.0 0.0 1.6 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 KEZ40482.1 - 3.6e-41 139.8 0.0 5.6e-41 139.2 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Pantoate_transf PF02548.10 KEZ40482.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase MR_MLE PF01188.16 KEZ40482.1 - 0.13 12.8 1.3 3 8.4 0.2 2.9 3 0 0 3 3 3 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Bromodomain PF00439.20 KEZ40483.1 - 2.3e-17 62.6 0.0 8.3e-17 60.8 0.0 1.9 2 0 0 2 2 2 1 Bromodomain BTB PF00651.26 KEZ40483.1 - 2.2e-07 30.8 0.0 4.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DNA_mis_repair PF01119.14 KEZ40484.1 - 9.9e-32 108.8 0.0 1.6e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DUF202 PF02656.10 KEZ40484.1 - 7.4e-17 61.3 1.5 1.6e-16 60.2 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) HATPase_c_3 PF13589.1 KEZ40484.1 - 2.1e-12 46.8 0.0 4.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEZ40484.1 - 3.8e-08 33.0 0.1 1e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT_2 PF13646.1 KEZ40486.1 - 0.00017 21.8 1.7 0.0066 16.7 0.1 3.7 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KEZ40486.1 - 0.016 15.2 2.2 4.2 7.7 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat SGT1 PF07093.6 KEZ40486.1 - 0.11 10.8 7.0 0.19 10.0 4.1 1.7 2 0 0 2 2 2 0 SGT1 protein Fzo_mitofusin PF04799.8 KEZ40486.1 - 0.15 11.4 1.2 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 fzo-like conserved region HEAT_EZ PF13513.1 KEZ40486.1 - 8.5 7.0 9.8 12 6.5 0.5 4.5 3 1 1 4 4 4 0 HEAT-like repeat DnaJ PF00226.26 KEZ40487.1 - 1.4e-13 50.3 1.4 3.5e-13 49.0 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain DEAD PF00270.24 KEZ40488.1 - 5.4e-45 152.9 0.0 1.3e-44 151.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ40488.1 - 1.9e-23 82.1 0.1 5.9e-22 77.3 0.1 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 KEZ40488.1 - 9.5e-22 76.5 1.4 2.8e-21 75.1 1.0 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 KEZ40488.1 - 0.02 14.6 0.0 0.082 12.7 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cation_efflux PF01545.16 KEZ40489.1 - 2.5e-69 233.5 5.2 3e-69 233.2 3.6 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KEZ40489.1 - 8.2e-07 28.3 4.9 1.7e-06 27.3 3.4 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter BPD_transp_2 PF02653.11 KEZ40489.1 - 0.0049 15.8 0.3 0.0049 15.8 0.2 1.7 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF1109 PF06532.6 KEZ40489.1 - 0.042 13.2 0.2 0.094 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) DUF3608 PF12257.3 KEZ40490.1 - 1.1e-71 240.9 0.0 2e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KEZ40490.1 - 6.6e-29 99.4 0.1 1.4e-28 98.4 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Nipped-B_C PF12830.2 KEZ40491.1 - 3.6e-47 160.4 1.9 3.6e-47 160.4 1.3 2.2 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KEZ40491.1 - 2.7e-10 39.9 2.1 4.2e-10 39.3 0.3 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KEZ40491.1 - 0.00013 21.7 4.8 0.033 14.2 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 KEZ40491.1 - 0.002 18.0 3.5 0.31 10.8 0.0 3.9 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KEZ40491.1 - 0.0031 15.8 0.6 0.02 13.2 0.0 2.4 2 1 0 2 2 2 1 Adaptin N terminal region TFIIS_C PF01096.13 KEZ40492.1 - 4.6e-15 54.9 0.6 4.6e-15 54.9 0.4 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.6 KEZ40492.1 - 5.6e-05 22.7 7.4 0.0036 16.9 0.3 2.3 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 KEZ40492.1 - 0.011 16.0 6.0 0.26 11.5 0.4 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar RNA_POL_M_15KD PF02150.11 KEZ40492.1 - 0.032 13.9 3.1 0.032 13.9 2.1 2.5 3 0 0 3 3 2 0 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 KEZ40492.1 - 0.045 13.4 1.3 0.045 13.4 0.9 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cys_rich_CPCC PF14206.1 KEZ40492.1 - 0.05 13.1 3.5 0.076 12.5 0.9 2.0 1 1 1 2 2 2 0 Cysteine-rich CPCC zf-ribbon_3 PF13248.1 KEZ40492.1 - 0.19 11.0 0.1 0.19 11.0 0.1 3.1 3 1 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KEZ40492.1 - 0.2 11.6 0.2 0.2 11.6 0.1 3.1 3 1 1 4 4 4 0 Zinc ribbon domain DUF2072 PF09845.4 KEZ40492.1 - 0.3 11.0 3.8 4.2 7.3 0.1 2.1 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) zf-C4_Topoisom PF01396.14 KEZ40492.1 - 0.45 10.0 0.1 0.45 10.0 0.1 2.9 2 1 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.1 KEZ40492.1 - 0.47 10.0 0.2 0.47 10.0 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 KEZ40492.1 - 0.7 9.5 6.5 1.6 8.4 0.1 2.5 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family Ribosomal_S27e PF01667.12 KEZ40492.1 - 0.93 9.0 9.1 10 5.7 3.4 2.8 2 1 0 2 2 2 0 Ribosomal protein S27 DZR PF12773.2 KEZ40492.1 - 7.6 6.4 12.9 74 3.2 6.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.11 KEZ40492.1 - 8.1 6.1 11.0 3.7 7.2 0.1 3.2 3 0 0 3 3 3 0 HIT zinc finger zf-LITAF-like PF10601.4 KEZ40492.1 - 8.2 6.3 9.3 13 5.7 0.5 2.6 2 2 0 2 2 2 0 LITAF-like zinc ribbon domain Zn_Tnp_IS91 PF14319.1 KEZ40492.1 - 8.4 5.9 8.0 0.24 10.9 0.2 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF2082 PF09855.4 KEZ40492.1 - 9.1 6.2 7.1 2.8 7.8 0.2 2.6 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) HEAT_2 PF13646.1 KEZ40493.1 - 4.3e-35 119.8 6.5 1.4e-16 60.4 0.0 4.1 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 KEZ40493.1 - 4.8e-23 79.2 4.9 4.1e-05 23.6 0.1 6.9 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KEZ40493.1 - 5.4e-13 49.0 5.3 0.0005 20.4 0.0 5.7 3 2 2 5 5 5 2 HEAT-like repeat HEAT PF02985.17 KEZ40493.1 - 3.6e-12 45.2 3.5 0.37 10.9 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 KEZ40493.1 - 0.012 15.3 0.9 1.4 8.9 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat GlnE PF03710.10 KEZ40493.1 - 0.047 12.9 0.2 5.3 6.2 0.0 2.5 2 1 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase HrpB1_HrpK PF09613.5 KEZ40493.1 - 0.07 12.6 0.6 0.17 11.4 0.4 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Cofilin_ADF PF00241.15 KEZ40494.1 - 1.8e-08 34.2 0.0 2.1e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 KEZ40495.1 - 2.2e-18 66.0 0.0 5.1e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 KEZ40496.1 - 8.4e-58 194.3 0.1 9.7e-58 194.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ40496.1 - 2.3e-18 66.8 0.0 3.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ40496.1 - 1.2e-07 31.1 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEZ40496.1 - 2.2e-06 27.2 0.0 1.2e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEZ40496.1 - 0.0016 18.3 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ40496.1 - 0.005 16.1 0.0 0.0095 15.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KEZ40496.1 - 0.058 12.9 1.9 0.66 9.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KEZ40496.1 - 0.067 12.3 0.1 0.12 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KEZ40496.1 - 0.07 12.5 0.6 0.69 9.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.18 KEZ40497.1 - 6.7e-32 110.6 0.2 2.3e-31 108.8 0.1 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEZ40497.1 - 7.3e-08 31.5 0.0 1.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KEZ40497.1 - 5.1e-06 26.4 0.1 4.1e-05 23.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KEZ40497.1 - 0.0031 17.3 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 KEZ40497.1 - 0.004 17.6 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KEZ40497.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Ras family MobB PF03205.9 KEZ40497.1 - 0.086 12.5 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KEZ40497.1 - 0.089 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KEZ40497.1 - 0.093 13.0 0.0 0.52 10.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KEZ40497.1 - 0.12 12.3 0.5 2.5 8.0 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain HrpB1_HrpK PF09613.5 KEZ40497.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Kelch_5 PF13854.1 KEZ40499.1 - 2.9e-12 46.2 4.2 4.2e-11 42.5 0.1 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 KEZ40499.1 - 3.8e-05 23.7 3.8 0.026 14.7 0.0 4.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KEZ40499.1 - 8.8e-05 21.9 0.3 2.1 7.9 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 KEZ40499.1 - 9.3e-05 22.1 1.6 5.7 6.7 0.0 4.4 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KEZ40499.1 - 0.017 15.2 6.2 0.22 11.7 0.2 4.2 4 1 0 4 4 4 0 Kelch motif Abhydrolase_6 PF12697.2 KEZ40500.1 - 1.3e-27 97.2 0.0 2.4e-27 96.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ40500.1 - 3.4e-13 49.7 0.0 1.1e-11 44.7 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ40500.1 - 5.5e-13 48.8 0.0 1.3e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KEZ40500.1 - 5.4e-05 22.7 0.0 9.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KEZ40500.1 - 0.00019 21.0 0.0 0.00052 19.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 KEZ40500.1 - 0.00056 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 KEZ40500.1 - 0.0066 16.7 0.1 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 KEZ40500.1 - 0.0092 15.4 0.0 4.5 6.6 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KEZ40500.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.8 KEZ40500.1 - 0.013 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DLH PF01738.13 KEZ40500.1 - 0.023 13.9 0.0 0.12 11.5 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KEZ40500.1 - 0.028 14.2 0.0 0.23 11.3 0.0 2.4 3 0 0 3 3 3 0 Putative lysophospholipase Chlorophyllase2 PF12740.2 KEZ40500.1 - 0.05 12.4 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KEZ40500.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S9 PF00326.16 KEZ40500.1 - 0.11 11.6 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.3 KEZ40500.1 - 0.14 11.4 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF2305 PF10230.4 KEZ40500.1 - 0.17 11.2 0.0 0.73 9.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PAS_9 PF13426.1 KEZ40501.1 - 3.2e-11 43.5 0.0 2.9e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain RGS PF00615.14 KEZ40501.1 - 2.7e-07 30.7 0.0 5.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.19 KEZ40501.1 - 0.022 14.5 0.0 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 PAS fold Glyoxalase PF00903.20 KEZ40502.1 - 1.6e-11 44.3 7.6 8e-09 35.5 2.8 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEZ40502.1 - 2.9e-11 43.9 3.4 1.3e-07 32.1 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KEZ40502.1 - 0.0014 18.5 0.7 0.065 13.2 0.1 2.8 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CRAL_TRIO PF00650.15 KEZ40503.1 - 3.7e-26 91.5 0.0 5.1e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEZ40503.1 - 6e-09 35.8 0.1 1.5e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DEAD PF00270.24 KEZ40504.1 - 1.3e-42 145.1 0.0 2.5e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KEZ40504.1 - 2e-25 88.0 0.1 5.3e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KEZ40504.1 - 5.5e-22 77.4 0.0 1.3e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ40504.1 - 0.013 15.3 3.4 0.019 14.8 0.0 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit PAPS_reduct PF01507.14 KEZ40505.1 - 3.3e-27 95.4 0.0 3.9e-19 69.1 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Epimerase PF01370.16 KEZ40506.1 - 6.1e-45 153.4 0.0 8.2e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KEZ40506.1 - 1.4e-23 82.6 0.0 2.4e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KEZ40506.1 - 9.6e-18 63.8 0.1 1.7e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KEZ40506.1 - 1.8e-14 53.3 0.2 1.7e-12 46.8 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEZ40506.1 - 3.8e-13 48.9 0.0 5.9e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KEZ40506.1 - 3.9e-12 46.4 0.1 6.6e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEZ40506.1 - 5.5e-09 36.2 0.0 1.4e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEZ40506.1 - 1.4e-08 34.6 0.1 2.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KEZ40506.1 - 1.6e-08 33.8 0.1 4.9e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein UDPG_MGDP_dh_N PF03721.9 KEZ40506.1 - 0.0021 17.4 0.2 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 KEZ40506.1 - 0.0061 15.5 0.0 0.0094 14.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 KEZ40506.1 - 0.015 14.2 0.2 0.028 13.3 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NmrA PF05368.8 KEZ40506.1 - 0.016 14.4 0.2 0.055 12.7 0.1 1.9 2 1 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.13 KEZ40506.1 - 0.038 13.6 0.1 0.081 12.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thrombin_light PF09396.5 KEZ40506.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Thrombin light chain ADH_zinc_N PF00107.21 KEZ40507.1 - 3.1e-32 110.8 0.1 4.5e-32 110.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ40507.1 - 4.1e-16 60.0 0.3 1.4e-15 58.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ40507.1 - 3.5e-13 49.2 0.3 1.4e-11 44.1 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KEZ40507.1 - 0.0098 15.9 1.0 0.18 11.8 0.3 2.2 2 0 0 2 2 2 1 NADH(P)-binding APH PF01636.18 KEZ40510.1 - 6.5e-05 22.7 0.2 0.00016 21.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4319 PF14203.1 KEZ40510.1 - 0.019 14.5 0.6 0.019 14.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4319) Septin PF00735.13 KEZ40511.1 - 4.1e-121 403.3 0.1 4.1e-121 403.3 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KEZ40511.1 - 2e-07 30.9 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KEZ40511.1 - 3.5e-05 24.1 1.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KEZ40511.1 - 5.7e-05 22.3 0.3 0.00039 19.6 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEZ40511.1 - 0.00011 21.6 2.1 0.00082 18.8 0.0 2.9 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KEZ40511.1 - 0.00034 20.1 0.7 0.0019 17.7 0.1 2.1 2 1 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 KEZ40511.1 - 0.0008 18.5 1.8 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 KEZ40511.1 - 0.0022 18.0 0.0 0.013 15.4 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 KEZ40511.1 - 0.0029 18.0 0.0 0.012 16.1 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KEZ40511.1 - 0.004 17.3 0.0 0.026 14.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ40511.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.17 KEZ40511.1 - 0.01 15.2 0.1 0.036 13.4 0.0 2.0 2 0 0 2 2 2 0 Ras family FtsK_SpoIIIE PF01580.13 KEZ40511.1 - 0.016 14.7 1.3 0.023 14.1 0.0 1.9 2 0 0 2 2 1 0 FtsK/SpoIIIE family MobB PF03205.9 KEZ40511.1 - 0.042 13.5 1.9 0.24 11.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEZ40511.1 - 0.042 14.0 0.8 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.1 KEZ40511.1 - 0.042 12.4 10.3 0.43 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KEZ40511.1 - 0.053 13.0 0.1 6.2 6.2 0.0 2.8 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 KEZ40511.1 - 0.082 12.0 6.3 0.14 11.3 4.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_24 PF13479.1 KEZ40511.1 - 0.11 12.0 0.5 0.2 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.18 KEZ40511.1 - 0.12 12.2 9.6 0.57 9.9 0.1 3.4 2 2 0 3 3 3 0 Dynamin family Strep_SA_rep PF06696.6 KEZ40511.1 - 0.3 10.8 1.9 0.32 10.8 0.1 1.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat YlqD PF11068.3 KEZ40511.1 - 0.34 10.9 10.6 0.68 9.9 7.3 1.5 1 0 0 1 1 1 0 YlqD protein Phage_GPO PF05929.6 KEZ40511.1 - 0.38 9.9 6.7 0.59 9.3 4.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IIGP PF05049.8 KEZ40511.1 - 0.96 8.1 5.5 0.23 10.2 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) IncA PF04156.9 KEZ40511.1 - 1.2 8.7 9.1 1.9 8.0 6.3 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 KEZ40511.1 - 1.5 6.6 7.8 2.7 5.7 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 KEZ40511.1 - 1.8 8.3 5.7 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF342 PF03961.8 KEZ40511.1 - 2.3 6.5 8.3 3.6 5.9 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) S4 PF01479.20 KEZ40512.1 - 1.4e-12 46.8 0.0 3.4e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KEZ40512.1 - 0.055 13.0 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 S4 domain rpo132 PF12415.3 KEZ40512.1 - 0.12 11.3 0.1 0.26 10.2 0.0 1.6 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase La PF05383.12 KEZ40513.1 - 3.9e-16 58.5 0.0 6.1e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KEZ40513.1 - 3e-09 36.3 0.2 6e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ40513.1 - 3.7e-08 33.2 0.0 7.6e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ40513.1 - 0.00028 20.6 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEZ40513.1 - 0.018 14.8 0.1 0.018 14.8 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif Ank_2 PF12796.2 KEZ40514.1 - 4.7e-55 183.8 17.7 1.4e-08 34.9 0.0 15.3 3 3 5 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ40514.1 - 7e-24 82.4 29.0 0.001 18.7 0.0 20.7 25 1 0 25 25 25 4 Ankyrin repeat Ank_4 PF13637.1 KEZ40514.1 - 4.8e-17 61.9 17.6 0.00028 21.3 0.0 13.9 15 2 2 17 17 17 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40514.1 - 1.4e-14 52.6 14.2 0.089 13.0 0.0 17.1 22 0 0 22 22 22 1 Ankyrin repeat Ank_5 PF13857.1 KEZ40514.1 - 6.4e-14 51.6 5.5 0.38 11.0 0.0 13.4 16 1 1 17 17 17 2 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KEZ40514.1 - 0.11 12.0 0.0 26 4.1 0.0 3.5 4 0 0 4 4 4 0 Shigella flexneri OspC protein MotB_plug PF13677.1 KEZ40515.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Sugar_tr PF00083.19 KEZ40516.1 - 5.7e-80 269.0 16.2 6.8e-80 268.8 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ40516.1 - 2.8e-30 105.2 32.4 2.2e-22 79.2 7.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ40516.1 - 6e-13 47.9 7.6 6.9e-09 34.5 0.2 3.4 4 0 0 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 KEZ40516.1 - 0.0019 16.4 3.6 0.0019 16.4 2.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KEZ40516.1 - 0.005 16.6 2.7 0.0088 15.8 0.1 2.8 3 0 0 3 3 3 1 MFS_1 like family Exo5 PF09810.4 KEZ40517.1 - 6.8e-106 354.1 0.0 8.9e-106 353.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease MARVEL PF01284.18 KEZ40518.1 - 9e-09 35.2 16.5 1.6e-08 34.4 11.5 1.4 1 0 0 1 1 1 1 Membrane-associating domain DSPc PF00782.15 KEZ40519.1 - 5.6e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEZ40519.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KEZ40519.1 - 0.012 15.8 0.1 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 KEZ40519.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) UPF0121 PF03661.8 KEZ40520.1 - 2.4e-10 40.0 0.9 3.8e-10 39.3 0.6 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Cyclin_N PF00134.18 KEZ40521.1 - 4.4e-11 42.4 0.0 8.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Palm_thioest PF02089.10 KEZ40522.1 - 5.5e-55 186.2 0.0 6.8e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 KEZ40522.1 - 2.7e-05 24.1 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L1 PF00687.16 KEZ40523.1 - 6.7e-58 195.6 2.4 6.7e-58 195.6 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF2508 PF10704.4 KEZ40523.1 - 0.0056 16.8 2.8 0.0056 16.8 1.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2508) DUF179 PF02622.10 KEZ40523.1 - 0.09 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized ACR, COG1678 LRAT PF04970.8 KEZ40523.1 - 0.1 12.5 0.0 0.33 10.8 0.0 1.9 2 1 0 2 2 2 0 Lecithin retinol acyltransferase zf-RING_2 PF13639.1 KEZ40525.1 - 6.8e-09 35.4 8.1 1.5e-08 34.3 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEZ40525.1 - 1.2e-07 31.6 2.1 2.9e-07 30.5 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KEZ40525.1 - 1.3e-06 28.2 8.8 4e-06 26.6 6.1 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KEZ40525.1 - 5.1e-05 23.0 2.7 0.00013 21.7 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KEZ40525.1 - 0.00036 20.5 8.5 0.00072 19.5 5.9 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.17 KEZ40525.1 - 0.0059 16.3 4.1 0.0059 16.3 2.9 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 KEZ40525.1 - 0.011 15.3 5.8 0.021 14.4 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ40525.1 - 0.02 14.9 8.9 0.046 13.7 6.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ40525.1 - 0.025 14.2 10.1 0.053 13.1 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KEZ40525.1 - 0.16 11.9 7.8 0.31 11.0 5.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 KEZ40525.1 - 1.1 9.1 9.0 2.1 8.1 6.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 KEZ40525.1 - 3.8 7.2 7.8 8.3 6.1 5.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KEZ40525.1 - 5.3 6.7 7.3 19 4.9 5.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 KEZ40526.1 - 1.8e-40 138.7 0.0 2.2e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40526.1 - 4.3e-15 55.4 0.0 6.6e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ40526.1 - 0.053 13.2 0.2 6.1 6.4 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KEZ40526.1 - 0.14 11.0 0.0 0.39 9.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like muHD PF10291.4 KEZ40527.1 - 3.7e-63 213.0 0.0 6.5e-63 212.3 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KEZ40527.1 - 5.8e-10 39.2 0.6 1.7e-09 37.7 0.0 2.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain IncFII_repA PF02387.10 KEZ40527.1 - 0.02 14.0 0.3 0.037 13.2 0.2 1.3 1 0 0 1 1 1 0 IncFII RepA protein family MAD PF05557.8 KEZ40528.1 - 3.2e-51 174.3 63.0 6e-51 173.4 43.7 1.4 1 1 0 1 1 1 1 Mitotic checkpoint protein Mmp37 PF09139.6 KEZ40529.1 - 1e-123 412.5 0.0 1.4e-123 412.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 CBM_1 PF00734.13 KEZ40530.1 - 7.3e-09 35.1 8.7 1.9e-08 33.8 6.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_transf_22 PF03901.12 KEZ40531.1 - 1.8e-82 277.6 14.8 2.1e-82 277.3 10.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2678 PF10856.3 KEZ40531.1 - 1.5 8.6 5.8 3.4 7.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) SH3_9 PF14604.1 KEZ40532.1 - 9.5e-11 41.1 0.0 1.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ40532.1 - 1.6e-06 27.4 0.0 2.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KEZ40532.1 - 2.2e-06 27.0 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.5 KEZ40532.1 - 0.015 14.5 0.0 0.015 14.5 0.0 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Syndecan PF01034.15 KEZ40532.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.1 KEZ40532.1 - 0.082 12.6 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family SCF PF02404.10 KEZ40532.1 - 0.096 11.8 0.1 0.14 11.2 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor DUF4448 PF14610.1 KEZ40532.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rax2 PF12768.2 KEZ40532.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity ATG22 PF11700.3 KEZ40532.1 - 0.14 10.5 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Podoplanin PF05808.6 KEZ40532.1 - 0.24 10.9 2.8 0.23 11.0 0.8 1.8 1 1 1 2 2 2 0 Podoplanin P12 PF12669.2 KEZ40532.1 - 0.56 10.4 4.0 1.1 9.4 1.4 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Mito_carr PF00153.22 KEZ40533.1 - 3.3e-60 199.8 5.3 3.2e-20 71.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.17 KEZ40534.1 - 2.6e-08 34.0 0.0 3.9e-06 27.0 0.0 3.0 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.13 KEZ40535.1 - 4e-40 137.7 0.2 5.1e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.2 KEZ40536.1 - 4.5e-12 46.0 0.0 4.3e-11 42.8 0.0 2.6 3 1 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 KEZ40536.1 - 1.6e-09 37.5 0.5 4.8e-09 36.0 0.2 1.8 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex HNOB PF07700.10 KEZ40536.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding zf-NADH-PPase PF09297.6 KEZ40536.1 - 0.18 11.3 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Cation_efflux PF01545.16 KEZ40537.1 - 6.6e-56 189.4 2.9 7.2e-55 186.0 2.2 1.9 2 0 0 2 2 2 1 Cation efflux family Glyco_trans_1_4 PF13692.1 KEZ40538.1 - 1.6e-22 80.1 0.0 3e-21 75.9 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEZ40538.1 - 0.00046 20.3 0.1 0.00089 19.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KEZ40538.1 - 0.0022 18.2 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 UQ_con PF00179.21 KEZ40539.1 - 1.6e-37 128.0 0.0 1.7e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ40539.1 - 0.0022 17.7 0.0 0.0037 16.9 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B TP_methylase PF00590.15 KEZ40540.1 - 3e-21 76.1 0.1 4.9e-21 75.4 0.1 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pyridox_oxidase PF01243.15 KEZ40541.1 - 8.4e-10 38.5 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CoA_binding_2 PF13380.1 KEZ40542.1 - 4.9e-28 97.6 0.0 6.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.7 KEZ40543.1 - 1.4e-18 67.1 0.0 2.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40543.1 - 2.5e-15 57.0 0.2 1.7e-14 54.3 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40543.1 - 2.3e-12 46.7 0.0 3.2e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ40543.1 - 7.7e-12 45.4 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ40543.1 - 3.9e-09 36.8 0.0 6.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ40543.1 - 9.6e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ40543.1 - 1.6e-07 30.6 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEZ40543.1 - 2.9e-05 24.0 0.1 8.3e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ40543.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 KEZ40543.1 - 0.0031 17.1 0.0 0.033 13.8 0.0 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase tRNA_U5-meth_tr PF05958.6 KEZ40543.1 - 0.023 13.3 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DREV PF05219.7 KEZ40543.1 - 0.038 12.8 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.7 KEZ40543.1 - 0.039 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KEZ40543.1 - 0.043 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KEZ40543.1 - 0.058 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase EF-hand_7 PF13499.1 KEZ40544.1 - 6.3e-15 55.0 0.1 4e-10 39.6 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 KEZ40544.1 - 5.5e-13 48.6 0.0 5.4e-07 29.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 KEZ40544.1 - 7.5e-12 44.0 0.1 0.0018 17.9 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KEZ40544.1 - 1.6e-10 39.5 0.2 0.012 14.8 0.0 4.3 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 KEZ40544.1 - 1.3e-07 31.1 0.2 0.00034 20.1 0.0 3.5 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 KEZ40544.1 - 0.025 13.9 0.9 2.2 7.7 0.7 3.2 3 0 0 3 3 3 0 EF hand Peptidase_M3 PF01432.15 KEZ40545.1 - 1.4e-152 508.9 0.0 1.8e-152 508.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 KEZ40545.1 - 0.045 13.8 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Effector protein BIR PF00653.16 KEZ40546.1 - 1.5e-39 134.2 2.7 2.2e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Trypan_PARP PF05887.6 KEZ40546.1 - 7e-05 22.6 26.7 7e-05 22.6 18.5 5.6 2 1 3 5 5 5 1 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.11 KEZ40547.1 - 7.3e-13 47.9 31.1 7.3e-13 47.9 21.6 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily NDUF_B12 PF08122.7 KEZ40547.1 - 0.091 12.5 2.2 0.61 9.8 0.0 3.4 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family F-box-like PF12937.2 KEZ40548.1 - 9.7e-06 25.2 1.4 1.7e-05 24.4 0.4 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEZ40548.1 - 0.00016 21.2 0.5 0.00037 20.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KEZ40548.1 - 0.0072 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like domain Glyco_hydro_61 PF03443.9 KEZ40549.1 - 1.8e-62 211.0 0.0 2.3e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KEZ40549.1 - 0.026 14.5 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SUR7 PF06687.7 KEZ40550.1 - 2.3e-10 40.4 0.0 3.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF1510 PF07423.6 KEZ40550.1 - 0.034 13.5 7.1 0.055 12.8 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Atrophin-1 PF03154.10 KEZ40550.1 - 0.076 11.1 13.0 0.12 10.4 9.0 1.2 1 0 0 1 1 1 0 Atrophin-1 family Fig1 PF12351.3 KEZ40550.1 - 0.12 12.2 0.4 0.17 11.7 0.3 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Ycf1 PF05758.7 KEZ40550.1 - 0.43 8.2 4.7 0.55 7.8 3.3 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 KEZ40550.1 - 4.7 7.2 13.8 6.8 6.6 9.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MIP-T3 PF10243.4 KEZ40550.1 - 5.6 5.3 20.8 7.5 4.8 14.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2781 PF10914.3 KEZ40551.1 - 4.5e-29 101.1 8.9 5.5e-29 100.8 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF1049 PF06305.6 KEZ40552.1 - 0.19 11.2 0.8 0.4 10.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Nucleoporin_C PF03177.9 KEZ40553.1 - 1.4e-132 443.2 2.6 1.7e-132 442.9 1.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KEZ40553.1 - 3e-87 293.0 0.2 4.5e-87 292.5 0.2 1.2 1 0 0 1 1 1 1 Nup133 N terminal like adh_short PF00106.20 KEZ40554.1 - 1.1e-25 90.5 0.1 1.5e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ40554.1 - 2.2e-13 50.5 0.0 3.1e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ40554.1 - 3.9e-08 33.1 0.1 7.3e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEZ40554.1 - 0.0025 17.8 0.1 0.0048 16.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEZ40554.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KEZ40554.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEZ40554.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF498 PF04430.9 KEZ40554.1 - 0.15 11.5 0.1 0.83 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Erg28 PF03694.8 KEZ40555.1 - 8.3e-43 144.9 0.0 1e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein Dpy19 PF10034.4 KEZ40555.1 - 0.11 10.6 0.5 0.14 10.3 0.4 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation GalP_UDP_tr_C PF02744.12 KEZ40556.1 - 7.4e-55 185.0 0.0 1.4e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 KEZ40556.1 - 5.7e-31 107.9 0.0 3.5e-29 102.1 0.0 2.3 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 KEZ40556.1 - 2.3e-06 28.0 0.0 2.2e-05 24.9 0.0 2.3 2 1 0 2 2 2 1 HIT domain SWIRM PF04433.12 KEZ40557.1 - 1.8e-12 47.2 0.0 5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KEZ40557.1 - 1.3e-11 43.8 5.6 2.3e-11 43.0 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KEZ40557.1 - 2.4e-06 27.4 0.0 9.1e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain SHOCT PF09851.4 KEZ40557.1 - 0.0096 15.3 0.7 0.053 13.0 0.5 2.3 1 0 0 1 1 1 1 Short C-terminal domain zf-C3HC4_2 PF13923.1 KEZ40557.1 - 2.2 8.3 5.6 4.7 7.3 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rhodanese PF00581.15 KEZ40558.1 - 6e-14 52.3 0.1 9.9e-13 48.4 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain ketoacyl-synt PF00109.21 KEZ40559.1 - 7.8e-56 189.3 0.8 1.4e-55 188.5 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 KEZ40559.1 - 1.8e-55 188.1 0.0 2.8e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KEZ40559.1 - 3.9e-53 179.8 0.1 1.3e-52 178.1 0.0 2.0 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.16 KEZ40559.1 - 1.3e-51 175.8 0.0 2.3e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain HD_3 PF13023.1 KEZ40559.1 - 1.5e-42 145.1 0.0 2.9e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 HD domain adh_short PF00106.20 KEZ40559.1 - 1.6e-41 141.9 0.9 6.8e-41 139.9 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEZ40559.1 - 3e-35 120.6 0.0 2.3e-34 117.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEZ40559.1 - 4.5e-20 71.5 0.5 2.2e-18 66.0 0.0 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KEZ40559.1 - 2.8e-19 69.4 0.0 7.5e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ40559.1 - 9.7e-11 41.6 0.0 3.7e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KEZ40559.1 - 1.5e-10 42.0 0.0 8.5e-10 39.6 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 KEZ40559.1 - 9.2e-10 38.3 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40559.1 - 2e-08 34.6 0.0 9.9e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40559.1 - 5.8e-08 33.3 0.0 1.7e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 KEZ40559.1 - 1e-07 31.6 0.0 3.8e-07 29.8 0.1 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEZ40559.1 - 1.7e-06 28.2 0.0 4.6e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 KEZ40559.1 - 1.4e-05 25.3 0.0 9.1e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ40559.1 - 0.0028 17.1 0.0 0.0068 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KEZ40559.1 - 0.022 13.8 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 KEZ40559.1 - 0.14 11.6 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.15 KEZ40559.1 - 0.39 9.7 0.0 0.71 8.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NOC3p PF07540.6 KEZ40561.1 - 0.014 15.6 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Nucleolar complex-associated protein DUF3433 PF11915.3 KEZ40562.1 - 6.4e-34 115.9 25.4 5.9e-19 68.0 0.5 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF3433) HAUS6_N PF14661.1 KEZ40563.1 - 6.4e-52 176.3 3.0 6.4e-52 176.3 2.1 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S21 PF01165.15 KEZ40564.1 - 2.6e-09 36.3 1.9 4e-09 35.7 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.12 KEZ40565.1 - 7.5e-11 41.9 0.4 2e-10 40.6 0.2 1.7 1 0 0 1 1 1 1 PWI domain BCL_N PF04714.8 KEZ40565.1 - 0.036 13.6 0.0 0.036 13.6 0.0 3.3 4 0 0 4 4 4 0 BCL7, N-terminal conserver region RRM_1 PF00076.17 KEZ40565.1 - 0.039 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ40565.1 - 0.06 13.3 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ADIP PF11559.3 KEZ40566.1 - 0.0026 17.6 0.7 0.0026 17.6 0.5 2.4 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding EAP30 PF04157.11 KEZ40566.1 - 0.015 14.4 2.1 0.073 12.2 0.2 2.6 2 1 0 2 2 2 0 EAP30/Vps36 family DUF2408 PF10303.4 KEZ40566.1 - 0.017 15.2 5.0 3.5 7.7 1.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Cep57_CLD_2 PF14197.1 KEZ40566.1 - 0.036 13.9 1.5 0.21 11.5 1.1 2.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DASH_Spc19 PF08287.6 KEZ40566.1 - 0.049 13.2 2.7 0.48 10.0 1.1 2.6 2 0 0 2 2 2 0 Spc19 DUF3847 PF12958.2 KEZ40566.1 - 0.17 11.6 8.6 1.4 8.7 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) HSA PF07529.8 KEZ40566.1 - 0.28 11.0 4.6 0.17 11.6 0.4 2.6 2 1 1 3 3 3 0 HSA Mnd1 PF03962.10 KEZ40566.1 - 0.34 10.5 12.4 0.73 9.4 2.9 3.0 2 1 0 3 3 3 0 Mnd1 family HrpB7 PF09486.5 KEZ40566.1 - 0.6 10.0 10.2 0.066 13.1 3.0 2.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) PspA_IM30 PF04012.7 KEZ40566.1 - 0.64 9.3 8.2 2.1 7.6 1.8 3.4 2 1 1 3 3 3 0 PspA/IM30 family APG17 PF04108.7 KEZ40566.1 - 0.69 8.6 7.4 6.5 5.4 0.0 2.6 2 1 0 2 2 2 0 Autophagy protein Apg17 Tropomyosin_1 PF12718.2 KEZ40566.1 - 0.79 9.5 8.9 0.18 11.6 1.0 2.9 3 0 0 3 3 3 0 Tropomyosin like Prefoldin PF02996.12 KEZ40566.1 - 0.81 9.3 6.2 6.6 6.4 0.3 3.2 3 2 1 4 4 4 0 Prefoldin subunit IFT57 PF10498.4 KEZ40566.1 - 0.94 8.1 6.9 0.16 10.6 0.1 2.4 2 1 1 3 3 3 0 Intra-flagellar transport protein 57 CCDC-167 PF15188.1 KEZ40566.1 - 1 9.3 5.4 2.4 8.1 0.8 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 APG6 PF04111.7 KEZ40566.1 - 1.5 7.7 9.8 0.98 8.3 2.1 2.5 2 1 0 2 2 2 0 Autophagy protein Apg6 DUF501 PF04417.7 KEZ40566.1 - 1.7 8.4 6.2 0.58 10.0 1.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF501) TBPIP PF07106.8 KEZ40566.1 - 1.8 8.0 9.5 2 7.9 1.5 3.1 3 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apt1 PF10351.4 KEZ40566.1 - 3.1 6.5 7.4 3.8 6.2 0.1 2.5 2 1 0 2 2 2 0 Golgi-body localisation protein domain IncA PF04156.9 KEZ40566.1 - 4.9 6.6 12.0 5.8 6.4 5.4 2.7 2 1 0 2 2 2 0 IncA protein ING PF12998.2 KEZ40566.1 - 6.2 7.1 8.6 8.8 6.6 0.1 3.6 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding CorA PF01544.13 KEZ40567.1 - 5.7e-13 48.5 1.0 1.4e-12 47.2 0.7 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_45 PF02015.11 KEZ40568.1 - 1.5e-23 83.9 5.4 1.9e-23 83.5 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Barwin PF00967.12 KEZ40568.1 - 0.016 14.9 0.1 0.016 14.9 0.1 1.5 2 0 0 2 2 2 0 Barwin family Keratin_B2 PF01500.12 KEZ40568.1 - 1.5 8.5 9.9 0.095 12.4 2.4 1.9 1 1 0 2 2 2 0 Keratin, high sulfur B2 protein Pkinase PF00069.20 KEZ40571.1 - 4.8e-69 232.3 0.0 6.3e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40571.1 - 2.6e-32 111.8 0.0 3.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KEZ40571.1 - 2.8e-11 43.7 2.4 7.8e-11 42.3 1.7 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KEZ40571.1 - 0.0016 17.4 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ40571.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGI PF00342.14 KEZ40572.1 - 1.3e-201 670.2 0.0 1.5e-201 670.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mannitol_dh_C PF08125.8 KEZ40573.1 - 4.5e-46 157.0 0.1 6.5e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KEZ40573.1 - 4.2e-20 72.2 0.2 5.8e-19 68.5 0.0 2.6 2 1 1 3 3 3 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 KEZ40573.1 - 0.0041 16.5 1.0 0.026 13.9 0.1 2.5 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Coatomer_WDAD PF04053.9 KEZ40574.1 - 1.4e-168 561.3 0.0 6.6e-168 559.0 0.0 2.0 3 0 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 KEZ40574.1 - 2.4e-48 160.3 7.5 7.1e-10 38.3 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KEZ40574.1 - 0.0003 20.5 0.1 1 9.1 0.0 4.1 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KEZ40574.1 - 0.00048 18.3 3.1 0.039 12.0 0.0 3.9 3 1 0 4 4 4 2 Nucleoporin Nup120/160 YmzC PF14157.1 KEZ40574.1 - 0.039 13.7 0.2 17 5.2 0.1 4.1 5 0 0 5 5 5 0 YmzC-like protein DUF917 PF06032.7 KEZ40576.1 - 7.2e-109 363.5 1.7 1.2e-108 362.8 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KEZ40576.1 - 2.1e-50 171.4 5.7 2.1e-49 168.1 1.1 3.2 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEZ40576.1 - 7.3e-28 97.2 2.4 3.5e-26 91.7 0.0 2.8 3 0 0 3 3 2 1 Hydantoinase/oxoprolinase N-terminal region Pyr_redox_3 PF13738.1 KEZ40576.1 - 3.3e-23 82.8 0.0 6.2e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ40576.1 - 1.3e-14 53.3 0.0 1.3e-12 46.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KEZ40576.1 - 1.3e-11 44.8 0.0 2.5e-10 40.5 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ40576.1 - 1.3e-09 37.4 0.1 5.6e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEZ40576.1 - 1.1e-06 28.6 0.0 4.5e-06 26.5 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ40576.1 - 2.1e-05 24.8 0.1 0.15 12.4 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ40576.1 - 0.00012 21.2 0.0 0.0032 16.5 0.0 3.0 4 0 0 4 4 4 1 FAD binding domain BcrAD_BadFG PF01869.15 KEZ40576.1 - 0.00051 19.4 3.3 0.0018 17.6 0.0 3.0 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family Shikimate_DH PF01488.15 KEZ40576.1 - 0.0012 18.9 0.1 0.72 9.9 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KEZ40576.1 - 0.0016 18.1 0.1 0.49 10.0 0.0 2.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KEZ40576.1 - 0.0017 16.8 0.4 0.0068 14.9 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 KEZ40576.1 - 0.0028 16.6 0.1 0.095 11.5 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KEZ40576.1 - 0.003 16.7 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KEZ40576.1 - 0.0038 16.1 0.4 0.1 11.4 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KEZ40576.1 - 0.004 16.7 0.1 0.011 15.3 0.0 1.7 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain MutL PF13941.1 KEZ40576.1 - 0.0043 15.4 0.4 0.068 11.4 0.0 2.2 2 0 0 2 2 2 1 MutL protein Amino_oxidase PF01593.19 KEZ40576.1 - 0.0047 16.0 0.1 0.12 11.3 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase TrkA_N PF02254.13 KEZ40576.1 - 0.0052 16.7 0.0 0.24 11.4 0.0 2.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 KEZ40576.1 - 0.0067 16.6 0.0 0.83 9.9 0.0 3.3 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 KEZ40576.1 - 0.007 16.2 0.0 6.4 6.5 0.0 3.2 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase SnoaL_2 PF12680.2 KEZ40576.1 - 0.014 15.7 0.7 0.069 13.5 0.0 2.5 2 0 0 2 2 2 0 SnoaL-like domain NAD_binding_9 PF13454.1 KEZ40576.1 - 0.031 14.0 0.2 14 5.4 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF4394 PF14339.1 KEZ40576.1 - 0.064 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) Glyco_hydro_61 PF03443.9 KEZ40577.1 - 3.5e-49 167.5 0.1 4e-49 167.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank PF00023.25 KEZ40578.1 - 0.0036 17.0 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 KEZ40578.1 - 0.027 14.9 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.19 KEZ40578.1 - 0.047 13.7 0.2 0.18 11.8 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Ank_2 PF12796.2 KEZ40578.1 - 0.049 13.9 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ40578.1 - 0.18 12.1 0.0 0.48 10.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat MFS_1 PF07690.11 KEZ40579.1 - 7.1e-19 67.7 15.9 9.9e-13 47.5 3.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40579.1 - 1.4e-06 27.2 4.7 0.00069 18.2 1.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KEZ40579.1 - 0.0035 15.5 4.8 0.046 11.9 0.1 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KEZ40579.1 - 0.011 15.4 0.5 0.024 14.3 0.3 1.6 1 0 0 1 1 1 0 MFS_1 like family Pkinase PF00069.20 KEZ40580.1 - 5.3e-63 212.6 0.0 7.3e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40580.1 - 3.6e-42 144.2 0.0 4.8e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ40580.1 - 9.1e-08 31.3 0.0 4.9e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEZ40580.1 - 0.00019 20.5 0.2 0.00032 19.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEZ40580.1 - 0.01 15.1 0.1 0.019 14.3 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KEZ40580.1 - 0.019 14.3 0.0 0.037 13.3 0.0 1.4 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KEZ40580.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 KEZ40580.1 - 0.22 11.2 2.3 1.1 8.9 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Terpene_synth_C PF03936.11 KEZ40581.1 - 0.0018 17.5 0.0 0.0023 17.2 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Phytase PF02333.10 KEZ40583.1 - 2e-65 221.0 0.4 4.9e-64 216.4 0.1 2.2 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.8 KEZ40583.1 - 5.7e-05 23.1 37.6 0.02 15.0 11.1 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 KEZ40583.1 - 1 9.6 12.1 1.9 8.7 2.2 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF DUF1996 PF09362.5 KEZ40584.1 - 3.4e-85 285.4 0.7 3.4e-85 285.4 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) CFEM PF05730.6 KEZ40585.1 - 5.1e-64 212.0 84.9 7.9e-09 35.2 1.2 9.2 9 1 1 10 10 10 8 CFEM domain DUF1219 PF06755.7 KEZ40585.1 - 0.00038 19.9 0.1 53 3.3 0.0 5.4 6 0 0 6 6 6 0 Protein of unknown function (DUF1219) DUF2148 PF09918.4 KEZ40585.1 - 0.54 10.0 6.1 1.3e+02 2.3 0.0 5.3 6 0 0 6 6 6 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) DUF1363 PF07101.6 KEZ40585.1 - 3 7.9 9.0 46 4.0 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1363) AA_permease_2 PF13520.1 KEZ40586.1 - 1.8e-34 118.9 43.8 3.2e-34 118.1 30.3 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ40586.1 - 6.9e-16 57.6 35.1 6.9e-16 57.6 24.3 2.0 1 1 1 2 2 2 2 Amino acid permease HORMA PF02301.13 KEZ40587.1 - 1.3e-44 152.2 0.0 1.7e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 HORMA domain UCH PF00443.24 KEZ40588.1 - 2e-44 151.7 0.0 3.2e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KEZ40588.1 - 1.1e-22 79.8 10.3 1.3e-18 66.8 1.2 3.1 2 1 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KEZ40588.1 - 1.4e-22 78.8 1.0 4e-11 42.4 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.1 KEZ40588.1 - 1.1e-19 71.0 0.0 6.7e-19 68.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Eapp_C PF10238.4 KEZ40588.1 - 0.026 14.4 0.4 0.026 14.4 0.3 3.1 2 2 1 3 3 3 0 E2F-associated phosphoprotein NifU_N PF01592.11 KEZ40589.1 - 1.5e-51 173.6 0.0 2.1e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain RPE65 PF03055.10 KEZ40590.1 - 1e-108 364.0 0.0 1.1e-108 363.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF221 PF02714.10 KEZ40593.1 - 7.6e-85 284.6 24.4 9.9e-66 221.8 6.3 2.3 1 1 1 2 2 2 2 Domain of unknown function DUF221 DUF3779 PF12621.3 KEZ40593.1 - 1.4e-25 88.9 0.1 2.7e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KEZ40593.1 - 0.08 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) DEAD PF00270.24 KEZ40594.1 - 2.2e-49 167.2 0.0 2e-47 160.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ40594.1 - 9.3e-29 99.1 0.0 7.2e-28 96.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KEZ40594.1 - 0.014 13.8 0.0 0.014 13.8 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1253) MIP-T3 PF10243.4 KEZ40594.1 - 0.16 10.4 49.8 0.31 9.4 34.5 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CMS1 PF14617.1 KEZ40594.1 - 0.48 9.4 0.0 0.48 9.4 0.0 4.0 2 1 2 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit Rft-1 PF04506.8 KEZ40595.1 - 5.7e-86 289.0 0.5 8.7e-86 288.4 0.3 1.2 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.1 KEZ40595.1 - 0.0077 15.7 4.0 0.0077 15.7 2.8 3.8 4 0 0 4 4 4 2 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.9 KEZ40596.1 - 3.7e-24 85.7 5.2 1.3e-23 83.9 3.6 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KEZ40596.1 - 1.7e-12 46.6 0.0 4.2e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 KEZ40596.1 - 9.7e-12 45.1 5.3 1.2e-11 44.8 0.9 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ40596.1 - 1.5e-07 31.6 0.0 0.00015 21.8 0.0 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ40596.1 - 5.5e-05 22.2 0.1 0.19 10.6 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.1 KEZ40596.1 - 6.3e-05 22.6 0.0 0.00028 20.5 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.1 KEZ40596.1 - 0.00027 21.1 0.0 0.00074 19.7 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal DAO PF01266.19 KEZ40596.1 - 0.00043 19.2 8.5 0.014 14.3 0.2 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ40596.1 - 0.0041 16.9 3.0 2.4 7.9 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KEZ40596.1 - 0.0096 16.1 0.7 0.07 13.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Malic_M PF03949.10 KEZ40596.1 - 0.03 13.8 0.2 0.061 12.8 0.0 1.6 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Tropomyosin_1 PF12718.2 KEZ40597.1 - 4.3e-05 23.3 21.9 4.3e-05 23.3 15.2 1.9 1 1 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KEZ40597.1 - 0.01 14.9 29.9 0.037 13.1 20.7 1.9 1 1 0 1 1 1 0 Tropomyosin Med9 PF07544.8 KEZ40597.1 - 0.014 15.1 3.3 0.014 15.1 2.3 3.5 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 KEZ40597.1 - 0.31 10.6 34.4 0.032 13.8 10.3 3.0 1 1 2 3 3 3 0 IncA protein AAA_13 PF13166.1 KEZ40597.1 - 0.4 9.0 10.0 0.65 8.3 7.0 1.2 1 0 0 1 1 1 0 AAA domain HR1 PF02185.11 KEZ40597.1 - 0.41 10.4 16.4 3.1 7.6 4.6 3.7 2 1 1 3 3 3 0 Hr1 repeat BLOC1_2 PF10046.4 KEZ40597.1 - 0.62 10.2 7.7 0.73 10.0 4.4 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Striatin PF08232.7 KEZ40597.1 - 0.75 10.1 21.7 0.26 11.5 8.3 3.4 1 1 1 2 2 2 0 Striatin family TMPIT PF07851.8 KEZ40597.1 - 2.2 7.2 8.4 1.6 7.6 5.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.5 KEZ40597.1 - 3.7 7.6 13.2 1.6 8.8 3.3 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 KEZ40597.1 - 4.4 5.6 6.5 4.1 5.7 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) PspB PF06667.7 KEZ40597.1 - 6.3 6.8 6.1 9.2 6.2 1.1 3.0 1 1 1 2 2 2 0 Phage shock protein B CENP-F_leu_zip PF10473.4 KEZ40597.1 - 6.5 6.6 28.4 1.9 8.3 11.9 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_trans PF04082.13 KEZ40598.1 - 1.1e-22 80.1 0.0 1.9e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40598.1 - 1.6e-08 34.3 10.0 2.7e-08 33.5 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 KEZ40599.1 - 3.7e-20 71.9 0.0 6.5e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KEZ40599.1 - 9.4e-14 51.4 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KEZ40599.1 - 1e-12 48.3 0.0 2.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Ribosomal_L22 PF00237.14 KEZ40601.1 - 5.3e-10 39.1 0.1 1.4e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e EURL PF06937.6 KEZ40601.1 - 0.06 12.7 0.8 0.092 12.1 0.5 1.2 1 0 0 1 1 1 0 EURL protein CFEM PF05730.6 KEZ40602.1 - 5.1e-08 32.6 10.4 9.3e-08 31.7 7.2 1.4 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 KEZ40602.1 - 0.0054 16.0 4.0 0.0054 16.0 2.7 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.6 KEZ40602.1 - 0.016 14.4 0.1 0.019 14.1 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.1 KEZ40602.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family UPF0560 PF10577.4 KEZ40602.1 - 0.72 8.0 7.7 1.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 FAP PF07174.6 KEZ40602.1 - 1.8 7.7 19.4 2.7 7.2 13.4 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PAT1 PF09770.4 KEZ40602.1 - 2.2 6.3 6.8 2.8 6.0 4.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 KEZ40602.1 - 7.6 4.6 9.1 9 4.4 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein GST_C PF00043.20 KEZ40603.1 - 3.5e-13 49.3 0.0 9e-13 48.0 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEZ40603.1 - 1.3e-10 41.0 0.1 3.5e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEZ40603.1 - 1.1e-06 29.0 0.0 1.8e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEZ40603.1 - 6.7e-06 26.1 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ40603.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Methyltransf_2 PF00891.13 KEZ40604.1 - 1.7e-26 92.9 0.1 1e-24 87.1 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase DUF4423 PF14394.1 KEZ40604.1 - 0.0056 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) AMP-binding PF00501.23 KEZ40605.1 - 4.5e-78 262.5 0.0 5.6e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ40605.1 - 2e-14 54.2 0.2 9.4e-14 52.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peptidase_M24 PF00557.19 KEZ40606.1 - 1.1e-40 139.4 0.0 1.4e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KEZ40606.1 - 0.00018 21.2 5.0 0.00018 21.2 3.5 1.9 2 0 0 2 2 2 1 MYND finger Pyr_redox_3 PF13738.1 KEZ40607.1 - 8.3e-29 101.0 0.0 3.4e-28 99.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_12 PF08242.7 KEZ40607.1 - 1.7e-17 63.6 0.0 6.9e-17 61.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain FMO-like PF00743.14 KEZ40607.1 - 9.1e-17 60.4 0.0 1.5e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Methyltransf_23 PF13489.1 KEZ40607.1 - 5e-14 52.3 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40607.1 - 7.9e-10 39.1 0.0 1.2e-08 35.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40607.1 - 1.3e-09 37.8 0.0 5.5e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ40607.1 - 5e-09 36.4 0.0 1.5e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain NAD_binding_8 PF13450.1 KEZ40607.1 - 7.3e-09 35.5 0.0 7.9e-07 29.0 0.0 3.7 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Ubie_methyltran PF01209.13 KEZ40607.1 - 3.7e-08 32.7 0.0 7.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KEZ40607.1 - 1.8e-07 31.7 0.0 7.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox_2 PF07992.9 KEZ40607.1 - 7.3e-07 29.2 0.0 1.5e-05 24.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ40607.1 - 1.3e-06 27.6 0.0 3.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ40607.1 - 0.00021 21.0 0.1 0.14 11.8 0.1 4.3 4 1 0 4 4 4 1 FAD-NAD(P)-binding Methyltransf_16 PF10294.4 KEZ40607.1 - 0.0021 17.5 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ40607.1 - 0.0052 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.22 KEZ40607.1 - 0.0057 17.0 0.2 7.9 6.9 0.0 3.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ40607.1 - 0.05 12.4 1.1 0.31 9.9 0.1 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase DREV PF05219.7 KEZ40607.1 - 0.051 12.4 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase 2-Hacid_dh_C PF02826.14 KEZ40607.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_28 PF02636.12 KEZ40607.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 KEZ40607.1 - 0.12 13.2 0.1 0.58 11.0 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase domain Lycopene_cycl PF05834.7 KEZ40607.1 - 0.13 11.1 0.0 0.27 10.1 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 KEZ40607.1 - 0.15 11.1 0.0 1 8.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family RrnaAD PF00398.15 KEZ40607.1 - 0.2 10.6 0.0 0.4 9.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UbiA PF01040.13 KEZ40608.1 - 3.1e-08 33.1 0.2 3.8e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2627 PF11118.3 KEZ40608.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) p450 PF00067.17 KEZ40609.1 - 6e-72 242.6 0.0 6.8e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 KEZ40610.1 - 2.7e-19 70.0 0.0 4.2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) EthD PF07110.6 KEZ40611.1 - 6.8e-15 55.7 0.2 1e-14 55.2 0.1 1.3 1 0 0 1 1 1 1 EthD domain AMP-binding PF00501.23 KEZ40612.1 - 5.7e-83 278.6 0.0 8.7e-83 278.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KEZ40612.1 - 4.4e-69 232.7 0.0 4.9e-68 229.3 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEZ40612.1 - 2.4e-54 183.7 0.3 1.1e-52 178.2 0.0 3.0 2 0 0 2 2 2 1 KR domain Condensation PF00668.15 KEZ40612.1 - 2.9e-51 174.1 0.2 5e-51 173.3 0.1 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 KEZ40612.1 - 2.1e-50 171.5 0.0 3.6e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEZ40612.1 - 1.2e-46 159.5 0.0 4e-46 157.8 0.0 1.9 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 KEZ40612.1 - 2.5e-45 154.3 1.6 2.4e-41 141.4 0.0 3.4 3 0 0 3 3 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 KEZ40612.1 - 1.8e-37 128.5 0.0 7.4e-37 126.6 0.0 2.1 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KEZ40612.1 - 4.1e-31 107.2 0.1 2e-30 105.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEZ40612.1 - 3e-18 65.8 0.2 1.1e-09 38.3 0.0 3.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 KEZ40612.1 - 5.1e-15 55.5 0.0 9.2e-11 41.6 0.0 2.8 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KEZ40612.1 - 3.5e-11 43.2 0.0 1.1e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 KEZ40612.1 - 3.4e-06 27.9 0.0 1.8e-05 25.5 0.0 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KEZ40612.1 - 2.2e-05 23.3 0.0 0.01 14.5 0.0 2.6 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.7 KEZ40612.1 - 0.00019 21.8 0.0 0.00078 19.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40612.1 - 0.00053 20.5 0.0 0.024 15.2 0.0 3.4 2 0 0 2 2 2 1 Methyltransferase domain F420_oxidored PF03807.12 KEZ40612.1 - 0.00091 19.6 0.1 0.0064 16.8 0.0 2.5 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KEZ40612.1 - 0.0058 15.5 0.1 0.39 9.5 0.0 2.6 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 KEZ40612.1 - 0.0077 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.19 KEZ40612.1 - 0.02 15.1 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KEZ40612.1 - 0.039 14.4 0.0 0.16 12.4 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.8 KEZ40612.1 - 0.21 10.7 0.0 2.9 7.0 0.0 2.6 3 0 0 3 3 3 0 NmrA-like family RmlD_sub_bind PF04321.12 KEZ40612.1 - 0.34 9.7 0.3 1.8 7.3 0.0 2.4 3 1 0 3 3 3 0 RmlD substrate binding domain Nckap1 PF09735.4 KEZ40612.1 - 0.59 7.5 0.0 0.89 6.9 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein DUF605 PF04652.11 KEZ40612.1 - 0.92 8.8 3.1 1.6 8.0 2.1 1.3 1 0 0 1 1 1 0 Vta1 like AATase PF07247.7 KEZ40612.1 - 3.5 6.0 0.3 9.8 4.5 0.0 1.7 2 0 0 2 2 2 0 Alcohol acetyltransferase RAP-1 PF03085.10 KEZ40612.1 - 6.5 6.0 0.0 13 5.0 0.0 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_23 PF13489.1 KEZ40613.1 - 2.5e-13 50.0 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ40613.1 - 0.0024 18.3 0.0 0.0057 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40613.1 - 0.0036 16.9 0.0 0.038 13.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ40613.1 - 0.039 13.9 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ribosomal_S6 PF01250.12 KEZ40613.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6 Abhydrolase_6 PF12697.2 KEZ40614.1 - 5.4e-19 68.9 0.6 7.7e-19 68.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ40614.1 - 7.9e-09 35.4 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEZ40614.1 - 7.8e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEZ40614.1 - 1.3e-05 24.8 0.2 3.7e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KEZ40614.1 - 0.0004 19.7 0.0 0.0011 18.2 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.20 KEZ40614.1 - 0.017 14.7 0.1 0.045 13.3 0.1 1.7 2 0 0 2 2 2 0 Lipase (class 3) p450 PF00067.17 KEZ40615.1 - 1.3e-27 96.5 0.0 1.5e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HA2 PF04408.18 KEZ40616.1 - 4.7e-19 68.2 0.0 1.7e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEZ40616.1 - 2.4e-12 46.5 0.0 5.5e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ40616.1 - 4.8e-10 39.1 0.1 1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KEZ40616.1 - 6.9e-07 29.0 0.0 2.5e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 KEZ40616.1 - 4.9e-06 26.7 0.3 1.5e-05 25.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEZ40616.1 - 0.0015 18.1 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KEZ40616.1 - 0.0039 17.4 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 KEZ40616.1 - 0.021 13.9 0.0 0.44 9.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 KEZ40616.1 - 0.026 14.0 0.0 0.073 12.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KEZ40616.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KEZ40616.1 - 0.042 12.6 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 KEZ40616.1 - 0.11 11.7 0.0 0.31 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KEZ40616.1 - 0.12 12.2 0.0 1.1 9.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF3554 PF12074.3 KEZ40617.1 - 1.6e-71 241.5 6.1 1e-70 238.8 0.5 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KEZ40617.1 - 8.2e-59 197.6 7.2 1.9e-58 196.4 5.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_2 PF13646.1 KEZ40617.1 - 2.4e-43 146.3 49.6 1.3e-10 41.3 0.0 15.8 9 3 5 14 14 14 10 HEAT repeats HEAT PF02985.17 KEZ40617.1 - 4.4e-37 122.8 38.8 0.0045 16.9 0.0 21.8 24 0 0 24 24 23 10 HEAT repeat HEAT_EZ PF13513.1 KEZ40617.1 - 2.3e-34 116.9 56.5 3.6e-07 30.4 0.0 22.6 17 3 8 25 25 24 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEZ40617.1 - 1.1e-13 51.3 0.0 1.7 9.0 0.0 9.4 7 3 2 9 9 9 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KEZ40617.1 - 2.4e-12 46.7 0.0 0.00071 18.9 0.0 6.0 5 2 2 7 7 7 2 CLASP N terminal ParcG PF10274.4 KEZ40617.1 - 3.6e-12 46.5 0.2 0.00051 19.9 0.0 4.8 4 0 0 4 4 4 3 Parkin co-regulated protein Adaptin_N PF01602.15 KEZ40617.1 - 5.3e-10 38.2 6.6 0.015 13.6 0.2 7.0 4 2 1 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.2 KEZ40617.1 - 3.8e-09 36.6 0.0 0.43 10.3 0.0 7.6 4 3 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 KEZ40617.1 - 7.7e-06 25.8 0.2 1.6 8.7 0.0 6.9 5 2 2 8 8 8 1 UME (NUC010) domain Ipi1_N PF12333.3 KEZ40617.1 - 5e-05 23.2 0.0 0.0047 16.8 0.0 4.5 6 0 0 6 6 5 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.3 KEZ40617.1 - 0.00061 18.6 2.3 3 6.4 0.0 4.8 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal DUF3535 PF12054.3 KEZ40617.1 - 0.0043 15.7 2.8 0.081 11.5 0.0 4.0 4 2 0 4 4 4 1 Domain of unknown function (DUF3535) Proteasom_PSMB PF10508.4 KEZ40617.1 - 0.15 10.2 7.6 2 6.6 0.3 3.9 4 1 0 4 4 4 0 Proteasome non-ATPase 26S subunit SHMT PF00464.14 KEZ40618.1 - 4.9e-200 663.9 0.0 5.8e-200 663.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KEZ40618.1 - 0.004 16.3 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KEZ40618.1 - 0.045 12.4 0.0 0.07 11.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V TAF8_C PF10406.4 KEZ40619.1 - 3.5e-12 46.1 0.1 7.4e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KEZ40619.1 - 1.2e-10 40.9 0.0 1.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Not3 PF04065.10 KEZ40619.1 - 0.031 13.5 1.8 0.066 12.4 0.6 1.8 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component WD40 PF00400.27 KEZ40620.1 - 6.1e-61 200.2 26.0 3.1e-11 42.6 0.6 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEZ40620.1 - 0.00014 20.1 5.8 0.17 9.9 0.2 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KEZ40620.1 - 0.02 13.2 0.0 2.3 6.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain BATS PF06968.8 KEZ40622.1 - 1.1e-27 95.6 0.0 3.4e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KEZ40622.1 - 8.5e-16 58.5 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_hydro_6 PF01341.12 KEZ40623.1 - 4.6e-96 321.7 1.3 5.9e-96 321.4 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.8 KEZ40624.1 - 5.1e-24 84.6 5.5 7.9e-24 84.0 3.8 1.2 1 0 0 1 1 1 1 OST3 / OST6 family CENP-F_leu_zip PF10473.4 KEZ40625.1 - 0.013 15.4 50.5 0.17 11.7 7.1 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 KEZ40625.1 - 4.8 4.3 36.3 9.9 3.3 25.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KEZ40625.1 - 6.8 6.2 49.3 0.49 9.9 7.3 3.1 1 1 1 2 2 2 0 IncA protein FtsJ PF01728.14 KEZ40626.1 - 7.5e-57 192.2 0.0 1e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KEZ40626.1 - 1.1e-05 25.2 0.1 2.2e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40626.1 - 0.015 14.9 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L18e PF00828.14 KEZ40627.1 - 6e-23 81.6 0.4 6e-23 81.6 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 KEZ40628.1 - 3.8e-74 244.4 1.3 1.7e-24 85.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KEZ40628.1 - 0.085 12.6 0.0 4.2 7.2 0.0 2.6 2 0 0 2 2 2 0 UcrQ family RRM_1 PF00076.17 KEZ40629.1 - 2.1e-08 33.6 0.0 3e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ40629.1 - 4.3e-06 26.4 0.0 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ40629.1 - 0.00016 21.5 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ40629.1 - 0.081 12.7 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MBOAT PF03062.14 KEZ40630.1 - 2.3e-26 92.6 18.9 2.3e-26 92.6 13.1 3.2 2 2 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KEZ40630.1 - 1.9e-06 27.8 3.7 6.2e-06 26.1 2.6 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Mt_ATP-synt_D PF05873.7 KEZ40630.1 - 0.0041 16.7 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CH PF00307.26 KEZ40631.1 - 1.3e-62 208.5 0.0 3.8e-17 62.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KEZ40631.1 - 9.2e-08 32.1 0.7 2e-06 27.8 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KEZ40631.1 - 2.4e-05 23.2 1.0 0.58 9.5 0.1 3.6 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.3 KEZ40631.1 - 0.011 15.3 0.0 18 5.1 0.0 3.5 3 0 0 3 3 3 0 CAMSAP CH domain EF-hand_6 PF13405.1 KEZ40631.1 - 0.015 15.1 0.4 0.41 10.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain DDHD PF02862.12 KEZ40632.1 - 2.9e-70 236.6 0.0 2.9e-70 236.6 0.0 2.6 2 1 0 2 2 2 1 DDHD domain Lipase_3 PF01764.20 KEZ40632.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RNA_pol_Rpb1_5 PF04998.12 KEZ40633.1 - 1.5e-83 280.3 0.2 2.4e-83 279.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KEZ40633.1 - 1.7e-66 223.2 0.0 3.5e-66 222.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 KEZ40633.1 - 1.1e-56 192.4 0.0 2.2e-48 165.2 0.0 2.3 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 KEZ40633.1 - 1.6e-36 125.3 0.0 4.9e-36 123.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KEZ40633.1 - 8.2e-30 102.7 0.3 2.4e-29 101.2 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF159 PF02586.9 KEZ40634.1 - 8.3e-55 185.5 0.0 1.7e-54 184.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised ACR, COG2135 GMC_oxred_N PF00732.14 KEZ40635.1 - 1.1e-28 100.3 0.2 3.7e-28 98.5 0.0 2.0 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ40635.1 - 2.2e-23 83.1 0.1 5.6e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ40635.1 - 1.3e-11 44.0 1.0 8.2e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ40635.1 - 2.5e-09 36.5 0.5 3.1e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ40635.1 - 0.00022 21.2 0.0 0.00068 19.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ40635.1 - 0.00032 20.8 0.1 0.046 13.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ40635.1 - 0.0007 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ40635.1 - 0.0018 16.8 0.0 0.003 16.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KEZ40635.1 - 0.02 13.9 0.6 1 8.3 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ40635.1 - 0.073 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KEZ40635.1 - 0.076 13.4 0.0 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ40635.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KEZ40635.1 - 0.12 11.2 0.1 0.57 8.9 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.11 KEZ40635.1 - 0.2 11.1 0.2 0.46 9.9 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_61 PF03443.9 KEZ40636.1 - 4.5e-57 193.3 0.0 5.5e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 KEZ40637.1 - 1.9e-37 129.2 0.2 2.3e-37 128.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alk_phosphatase PF00245.15 KEZ40638.1 - 3.9e-16 58.7 0.4 4.5e-16 58.5 0.3 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Alk_phosphatase PF00245.15 KEZ40639.1 - 4.5e-42 144.2 0.1 5.1e-42 144.0 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Peptidase_M28 PF04389.12 KEZ40639.1 - 0.094 12.4 0.3 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M28 RNA_pol_Rpb2_6 PF00562.23 KEZ40640.1 - 1.9e-127 425.2 0.5 6.4e-127 423.4 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEZ40640.1 - 7.1e-56 188.3 0.0 1.1e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KEZ40640.1 - 1.6e-45 154.8 0.1 3.7e-45 153.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KEZ40640.1 - 2.6e-30 104.4 0.0 6.5e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 KEZ40640.1 - 6.5e-23 80.2 0.3 2.2e-22 78.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KEZ40640.1 - 1.1e-22 79.6 0.4 3e-22 78.3 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.8 KEZ40640.1 - 1.4e-19 69.6 0.6 1.4e-19 69.6 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 V-ATPase_G PF03179.10 KEZ40642.1 - 1.4e-18 67.1 8.3 1.6e-18 66.8 5.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit NYD-SP28 PF14772.1 KEZ40642.1 - 0.0022 18.0 6.0 0.0027 17.7 4.2 1.0 1 0 0 1 1 1 1 Sperm tail LXG PF04740.7 KEZ40642.1 - 0.008 15.9 0.2 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily DUF87 PF01935.12 KEZ40642.1 - 0.026 14.3 0.2 0.029 14.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 Apolipoprotein PF01442.13 KEZ40642.1 - 0.065 12.7 4.5 0.079 12.4 3.1 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain YusW PF14039.1 KEZ40642.1 - 0.078 13.2 1.8 0.11 12.7 1.3 1.3 1 0 0 1 1 1 0 YusW-like protein Atg14 PF10186.4 KEZ40642.1 - 0.1 11.4 4.6 0.13 11.1 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DDRGK PF09756.4 KEZ40642.1 - 0.19 11.1 9.0 0.22 10.9 6.2 1.0 1 0 0 1 1 1 0 DDRGK domain OmpH PF03938.9 KEZ40642.1 - 0.25 11.2 6.7 0.31 10.9 4.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRF PF01765.14 KEZ40642.1 - 0.26 10.7 5.4 0.32 10.4 3.8 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF812 PF05667.6 KEZ40642.1 - 0.26 9.7 4.7 0.29 9.5 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KfrA_N PF11740.3 KEZ40642.1 - 0.52 10.7 7.9 0.71 10.3 5.5 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term IncA PF04156.9 KEZ40642.1 - 0.84 9.1 5.3 1.1 8.8 3.6 1.1 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 KEZ40642.1 - 0.95 7.8 6.4 1.1 7.6 4.4 1.0 1 0 0 1 1 1 0 AAA domain DUF4230 PF14014.1 KEZ40642.1 - 1.1 9.0 5.3 2.6 7.8 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) DUF2229 PF09989.4 KEZ40642.1 - 2.8 7.3 5.7 4 6.8 3.9 1.4 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF3987 PF13148.1 KEZ40642.1 - 4.9 5.6 9.5 5.7 5.3 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATP-synt_B PF00430.13 KEZ40642.1 - 8.8 6.1 12.7 20 4.9 8.8 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) CTNNBL PF08216.6 KEZ40643.1 - 4.9e-35 119.3 3.5 5.9e-35 119.1 0.1 2.7 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.6 KEZ40643.1 - 0.059 12.3 0.0 1.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Mo25-like His_Phos_1 PF00300.17 KEZ40644.1 - 8.2e-15 55.2 0.0 1.1e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LepA_C PF06421.7 KEZ40645.1 - 3.2e-37 126.7 3.1 6.1e-37 125.8 2.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 KEZ40645.1 - 4.3e-34 117.6 0.0 8e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEZ40645.1 - 1.1e-19 70.0 0.0 2.9e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus MIT PF04212.13 KEZ40645.1 - 2.4e-12 46.5 2.6 5.1e-12 45.5 1.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain EFG_II PF14492.1 KEZ40645.1 - 1.2e-06 28.2 0.0 5e-06 26.2 0.0 2.2 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KEZ40645.1 - 3.8e-05 23.7 0.1 0.00011 22.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 KEZ40645.1 - 0.00065 19.1 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Ras family UnbV_ASPIC PF07593.7 KEZ40645.1 - 0.11 12.2 0.7 6.2 6.5 0.1 2.6 2 0 0 2 2 2 0 ASPIC and UnbV Glyco_hydro_45 PF02015.11 KEZ40646.1 - 9.7e-86 286.9 18.4 1.8e-85 286.0 12.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 KEZ40646.1 - 8.5e-16 57.3 9.3 8.5e-16 57.3 6.4 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEZ40646.1 - 0.02 14.9 3.0 0.02 14.9 2.1 3.6 4 0 0 4 4 4 0 Toxin 7 UEV PF05743.8 KEZ40647.1 - 3.8e-37 126.6 0.1 6e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KEZ40647.1 - 6.6e-22 76.8 0.0 1.2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain STE2 PF02116.10 KEZ40648.1 - 4.8e-43 147.2 18.1 5.5e-43 147.0 12.6 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Sec1 PF00995.18 KEZ40649.1 - 1.1e-151 506.3 0.0 1.3e-151 506.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF1844 PF08899.6 KEZ40649.1 - 0.079 12.8 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) zf-CCCH PF00642.19 KEZ40650.1 - 8.9e-05 22.0 3.2 0.00016 21.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PK PF00224.16 KEZ40651.1 - 4.2e-166 551.8 4.6 5.2e-166 551.4 3.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KEZ40651.1 - 4.6e-29 100.3 0.0 1.2e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KEZ40651.1 - 0.002 17.0 1.0 0.0076 15.1 0.6 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family G_glu_transpept PF01019.16 KEZ40652.1 - 4.1e-143 477.5 1.2 1.5e-138 462.5 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase LytR_C PF13399.1 KEZ40652.1 - 0.089 13.1 1.2 23 5.4 0.1 3.6 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator Glutaredoxin PF00462.19 KEZ40653.1 - 6e-16 58.1 0.0 1.6e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Aldo_ket_red PF00248.16 KEZ40654.1 - 3.7e-52 176.9 0.0 4.2e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KEZ40655.1 - 4.3e-06 26.3 0.4 3.3e-05 23.5 0.0 2.7 3 1 0 3 3 3 1 F-box-like Cerato-platanin PF07249.7 KEZ40656.1 - 9e-51 170.8 0.4 1e-50 170.6 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin FMO-like PF00743.14 KEZ40657.1 - 4.4e-83 279.2 0.0 5.4e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEZ40657.1 - 1.7e-22 80.4 0.0 4.7e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ40657.1 - 7.2e-13 48.1 0.0 2.8e-09 36.3 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEZ40657.1 - 2e-09 37.5 0.0 3.7e-08 33.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ40657.1 - 9.4e-07 28.7 0.2 0.00028 20.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEZ40657.1 - 1.9e-06 27.7 0.0 4.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ40657.1 - 0.0021 18.4 0.2 2.3 8.6 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ40657.1 - 0.098 11.4 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Flavodoxin_1 PF00258.20 KEZ40657.1 - 0.19 11.7 0.0 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin Ank PF00023.25 KEZ40658.1 - 1.1e-17 62.8 0.3 1.3e-06 27.8 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KEZ40658.1 - 3.6e-14 52.8 0.2 6.5e-05 23.1 0.0 3.4 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEZ40658.1 - 2.9e-13 49.5 0.5 9.6e-06 25.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ40658.1 - 2.7e-12 46.8 0.3 9.9e-05 22.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ40658.1 - 4.1e-08 32.7 0.2 0.12 12.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KEZ40658.1 - 1e-06 28.3 0.2 6.2e-06 25.7 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Uteroglobin PF01099.12 KEZ40658.1 - 0.075 12.8 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Uteroglobin family Cu-oxidase_2 PF07731.9 KEZ40659.1 - 1.2e-22 79.8 1.0 2.6e-21 75.5 0.4 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KEZ40659.1 - 9.4e-11 41.8 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase RF-1 PF00472.15 KEZ40660.1 - 1.4e-32 111.8 1.3 2.6e-32 110.9 0.9 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KEZ40660.1 - 1.6e-24 85.8 0.0 9.2e-24 83.3 0.0 2.2 2 0 0 2 2 2 1 PCRF domain MIR PF02815.14 KEZ40660.1 - 0.011 15.3 0.4 0.024 14.1 0.2 1.6 1 1 0 1 1 1 0 MIR domain BNR_2 PF13088.1 KEZ40661.1 - 1.8e-06 27.4 0.1 8.5e-06 25.2 0.1 1.9 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KEZ40661.1 - 0.018 14.8 7.9 0.16 11.8 0.1 3.6 4 0 0 4 4 4 0 BNR/Asp-box repeat BNR_3 PF13859.1 KEZ40661.1 - 0.078 12.0 0.1 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 BNR repeat-like domain Kinesin PF00225.18 KEZ40662.1 - 1.8e-110 368.7 1.1 3.5e-110 367.8 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 KEZ40662.1 - 9.8e-37 125.7 0.1 2.8e-36 124.2 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 KEZ40662.1 - 2.4e-05 24.2 0.4 9.4e-05 22.3 0.3 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 KEZ40662.1 - 7.1e-05 22.8 0.0 0.0016 18.5 0.0 3.0 3 0 0 3 3 3 1 FHA domain PH PF00169.24 KEZ40662.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Peptidase_M1 PF01433.15 KEZ40663.1 - 2.5e-74 250.7 0.0 3.7e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KEZ40663.1 - 5.3e-43 146.0 0.0 9.3e-43 145.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KEZ40663.1 - 2.3e-19 69.6 0.1 3.7e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KEZ40663.1 - 0.12 12.3 1.4 0.51 10.3 1.0 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Uds1 PF15456.1 KEZ40664.1 - 3.6e-34 117.4 8.0 7.7e-34 116.3 5.5 1.6 1 0 0 1 1 1 1 Up-regulated During Septation SSP160 PF06933.6 KEZ40664.1 - 6.4 4.6 27.5 0.22 9.4 2.1 2.4 3 0 0 3 3 3 0 Special lobe-specific silk protein SSP160 Snf7 PF03357.16 KEZ40666.1 - 4.8e-34 117.2 22.0 4.8e-34 117.2 15.2 2.0 1 1 1 2 2 2 1 Snf7 Rhamno_transf PF11316.3 KEZ40666.1 - 0.043 13.0 0.2 0.063 12.4 0.1 1.4 1 1 0 1 1 1 0 Putative rhamnosyl transferase Bcr-Abl_Oligo PF09036.5 KEZ40666.1 - 0.076 12.9 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain ERp29 PF07749.7 KEZ40666.1 - 0.38 11.4 4.5 1 10.0 3.1 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain AAA_13 PF13166.1 KEZ40666.1 - 0.45 8.9 15.0 0.07 11.5 7.0 1.7 1 1 1 2 2 2 0 AAA domain zf-C4H2 PF10146.4 KEZ40666.1 - 0.53 10.2 17.3 0.78 9.7 12.0 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein GRA6 PF05084.8 KEZ40666.1 - 0.53 9.7 7.2 1.6 8.1 0.4 3.0 1 1 2 3 3 3 0 Granule antigen protein (GRA6) Allexi_40kDa PF05549.6 KEZ40666.1 - 0.64 9.2 6.5 0.45 9.7 3.3 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.6 KEZ40666.1 - 1.6 9.1 12.3 0.13 12.7 2.5 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HK97-gp10_like PF04883.7 KEZ40666.1 - 1.6 9.7 6.1 0.79 10.6 0.2 2.8 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component DUF3508 PF12018.3 KEZ40666.1 - 6.3 5.6 10.5 1.1 8.1 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Ten1 PF12658.2 KEZ40667.1 - 5e-31 107.0 0.0 5.7e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 KEZ40667.1 - 0.00027 20.4 0.0 0.00032 20.2 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Glyco_hydro_10 PF00331.15 KEZ40668.1 - 1.1e-62 211.9 0.1 9.2e-52 176.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 TauD PF02668.11 KEZ40669.1 - 8.6e-23 81.3 0.0 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Amidase PF01425.16 KEZ40671.1 - 5.2e-67 226.6 0.0 1.1e-34 120.0 0.0 2.1 1 1 1 2 2 2 2 Amidase Peptidase_M24 PF00557.19 KEZ40672.1 - 4e-45 153.9 0.1 5.5e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SRP-alpha_N PF04086.8 KEZ40672.1 - 0.71 9.1 9.5 3.9 6.7 7.3 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal AhpC-TSA_2 PF13911.1 KEZ40673.1 - 1.5e-16 60.3 0.0 4.2e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KEZ40673.1 - 3.5e-05 23.4 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEZ40673.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin Flavodoxin_4 PF12682.2 KEZ40674.1 - 0.021 14.1 0.0 0.046 13.0 0.0 1.6 1 1 0 1 1 1 0 Flavodoxin DUF2528 PF10800.3 KEZ40674.1 - 0.024 15.0 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Gp-FAR-1 PF05823.7 KEZ40674.1 - 0.072 13.0 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glyco_transf_8 PF01501.15 KEZ40675.1 - 1.4e-27 96.6 0.0 1.9e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KEZ40675.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative DUF243 PF03103.12 KEZ40676.1 - 0.0067 16.5 0.2 0.0084 16.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF243) WD40 PF00400.27 KEZ40677.1 - 3.4e-29 99.6 4.7 5.4e-09 35.5 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Aminotran_4 PF01063.14 KEZ40679.1 - 1.5e-19 70.3 0.0 2.2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV CTP_transf_2 PF01467.21 KEZ40680.1 - 3e-16 59.8 0.0 2.4e-14 53.6 0.0 3.4 2 1 0 2 2 2 1 Cytidylyltransferase MMR_HSR1 PF01926.18 KEZ40680.1 - 2.8e-08 33.7 0.0 1e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEZ40680.1 - 6.2e-06 25.4 0.0 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 AIG1 family DUF258 PF03193.11 KEZ40680.1 - 1.5e-05 24.2 0.0 3.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KEZ40680.1 - 0.00024 20.6 0.0 0.00086 18.8 0.0 1.9 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 KEZ40680.1 - 0.00026 19.9 0.0 0.00048 19.0 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) T2SE PF00437.15 KEZ40680.1 - 0.00061 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Dynamin_N PF00350.18 KEZ40680.1 - 0.0014 18.4 0.0 0.59 9.9 0.0 2.9 2 0 0 2 2 2 1 Dynamin family Septin PF00735.13 KEZ40680.1 - 0.0021 17.1 0.1 0.0058 15.6 0.0 1.7 1 1 0 1 1 1 1 Septin AAA_29 PF13555.1 KEZ40680.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KEZ40680.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KEZ40680.1 - 0.0063 16.5 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KEZ40680.1 - 0.012 14.5 0.0 0.038 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 KEZ40680.1 - 0.014 15.4 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KEZ40680.1 - 0.026 14.8 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 KEZ40680.1 - 0.026 14.2 0.1 0.17 11.5 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KEZ40680.1 - 0.04 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Sigma54_activat PF00158.21 KEZ40680.1 - 0.046 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4287 PF14117.1 KEZ40680.1 - 0.3 10.8 1.8 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) MFS_1 PF07690.11 KEZ40681.1 - 1.6e-28 99.4 55.9 1.2e-27 96.5 36.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 KEZ40681.1 - 0.00073 18.1 11.5 0.00073 18.1 8.0 3.2 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KEZ40682.1 - 5.3e-23 81.2 33.5 2.2e-15 56.2 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40682.1 - 1.5e-17 63.3 16.2 2.2e-17 62.8 10.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter ATG2_CAD PF13329.1 KEZ40683.1 - 8.3e-47 158.6 0.0 1.9e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 KEZ40683.1 - 2.7e-28 98.0 0.2 6.8e-28 96.7 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain Amino_oxidase PF01593.19 KEZ40684.1 - 4.2e-47 161.2 0.1 5.1e-46 157.6 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEZ40684.1 - 1.4e-14 53.8 0.1 2.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ40684.1 - 4.6e-06 25.7 0.0 0.00016 20.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ40684.1 - 7.8e-06 26.0 0.5 9.7e-05 22.5 0.1 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ40684.1 - 8.6e-06 26.0 0.4 4.3e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ40684.1 - 3.8e-05 22.3 1.3 0.0014 17.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ40684.1 - 0.00012 22.0 0.2 0.0028 17.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ40684.1 - 0.00032 19.8 0.3 0.00049 19.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KEZ40684.1 - 0.00045 19.1 0.2 0.00081 18.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEZ40684.1 - 0.0015 17.7 0.1 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 KEZ40684.1 - 0.0076 15.9 1.0 0.021 14.5 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KEZ40684.1 - 0.059 13.1 0.9 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 KEZ40684.1 - 0.12 11.1 0.3 0.21 10.4 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 KEZ40684.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KEZ40684.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Acyl-CoA_dh_1 PF00441.19 KEZ40685.1 - 5.5e-33 114.1 0.6 1.1e-32 113.2 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KEZ40685.1 - 5.4e-20 70.9 0.0 1.3e-19 69.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KEZ40685.1 - 8.7e-17 60.3 0.9 1.8e-16 59.3 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEZ40685.1 - 9.6e-07 29.3 0.9 3.1e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEZ40685.1 - 0.00029 21.0 0.0 0.00075 19.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tn916-Xis PF09035.5 KEZ40685.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Excisionase from transposon Tn916 zf-CCHC PF00098.18 KEZ40686.1 - 1.6e-51 169.9 63.2 1.8e-08 33.9 3.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KEZ40686.1 - 5.4e-12 45.1 44.3 0.053 13.1 0.2 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 KEZ40686.1 - 6.6e-07 28.9 51.1 0.23 11.2 0.3 7.1 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 KEZ40686.1 - 2.8e-05 23.5 45.8 0.026 14.0 0.7 7.1 3 2 4 7 7 7 5 Zinc knuckle zf-CCHC_6 PF15288.1 KEZ40686.1 - 0.00037 20.0 48.0 0.093 12.4 0.9 6.9 5 2 2 7 7 7 5 Zinc knuckle SAE2 PF08573.5 KEZ40687.1 - 2e-29 102.1 0.5 2e-29 102.1 0.4 3.0 4 0 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Toxin_67 PF15545.1 KEZ40687.1 - 0.025 14.4 0.0 0.41 10.5 0.0 2.8 2 0 0 2 2 2 0 Putative toxin 67 DUF1664 PF07889.7 KEZ40687.1 - 0.9 9.3 2.3 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 KEZ40687.1 - 5.2 7.4 11.3 0.29 11.4 1.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Exonuc_VII_L PF02601.10 KEZ40687.1 - 5.3 6.1 12.0 0.19 10.8 3.8 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit NYD-SP28_assoc PF14775.1 KEZ40687.1 - 6.5 6.5 9.8 1.7 8.4 2.9 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain UCH PF00443.24 KEZ40688.1 - 1.7e-46 158.4 0.0 3.9e-46 157.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ40688.1 - 9e-15 54.8 0.0 3.2e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF952 PF06108.7 KEZ40689.1 - 1.3e-22 79.4 0.0 1.6e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Nucleopor_Nup85 PF07575.8 KEZ40690.1 - 1e-13 50.4 0.0 3.2e-09 35.5 0.0 2.6 2 1 0 2 2 2 2 Nup85 Nucleoporin VWD PF00094.20 KEZ40690.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type D domain CDC45 PF02724.9 KEZ40690.1 - 2.6 5.9 17.4 4.4 5.2 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.5 KEZ40690.1 - 2.8 7.0 13.5 4 6.5 9.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.7 KEZ40690.1 - 6.7 5.8 27.5 16 4.6 18.7 1.9 2 0 0 2 2 2 0 SDA1 SpoIIIAH PF12685.2 KEZ40690.1 - 7.8 5.9 12.2 19 4.6 8.4 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein ADH_N PF08240.7 KEZ40691.1 - 1.2e-28 98.9 2.8 4.1e-28 97.3 1.9 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ40691.1 - 1.9e-19 69.5 0.3 3.6e-19 68.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KEZ40691.1 - 0.0025 17.2 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 KEZ40691.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GST_N PF02798.15 KEZ40691.1 - 0.084 13.0 0.0 17 5.6 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ThiF PF00899.16 KEZ40691.1 - 0.4 10.5 3.2 5.5 6.8 1.3 2.3 1 1 1 2 2 2 0 ThiF family APH PF01636.18 KEZ40692.1 - 0.038 13.7 0.5 0.2 11.3 0.3 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family MARVEL PF01284.18 KEZ40693.1 - 3e-13 49.8 10.8 4.3e-13 49.3 7.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.11 KEZ40693.1 - 0.035 12.8 8.2 0.22 10.2 3.6 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF308 PF03729.8 KEZ40693.1 - 0.12 12.3 12.8 0.87 9.6 0.1 3.1 2 1 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF4328 PF14219.1 KEZ40693.1 - 0.12 11.6 1.2 0.18 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Oxidored_q3 PF00499.15 KEZ40693.1 - 0.48 10.1 5.6 3.1 7.5 2.2 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 ABC2_membrane_5 PF13346.1 KEZ40693.1 - 0.5 9.6 7.7 0.93 8.7 5.4 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 KEZ40693.1 - 8 5.5 14.5 25 3.9 10.5 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein APG5 PF04106.7 KEZ40695.1 - 8.7e-43 146.0 0.0 2.2e-42 144.7 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 WSC PF01822.14 KEZ40696.1 - 4.8e-15 55.2 10.6 7.9e-15 54.5 7.4 1.4 1 0 0 1 1 1 1 WSC domain WD40 PF00400.27 KEZ40697.1 - 1.1e-33 113.8 15.3 2.6e-07 30.2 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KEZ40697.1 - 1.9e-05 23.0 1.8 0.43 8.6 0.1 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 KEZ40697.1 - 0.04 13.6 0.0 4 7.1 0.0 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KEZ40697.1 - 0.048 12.4 0.0 2.3 6.8 0.0 3.0 2 1 1 3 3 3 0 Nup133 N terminal like DUF3039 PF11238.3 KEZ40698.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Propeptide_C25 PF08126.6 KEZ40698.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Propeptide_C25 Zn_clus PF00172.13 KEZ40700.1 - 6.6e-09 35.5 14.3 1.1e-08 34.8 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3373 PF11853.3 KEZ40700.1 - 0.073 11.5 0.2 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Ribosomal_L22e PF01776.12 KEZ40701.1 - 8.9e-47 157.7 1.9 1e-46 157.5 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Ribosomal_S4 PF00163.14 KEZ40702.1 - 1.1e-13 51.3 1.7 1.5e-13 50.8 0.8 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEZ40702.1 - 5.2e-12 44.9 0.0 1.5e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 S4 domain THDPS_N_2 PF14805.1 KEZ40702.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal UPF0302 PF08864.5 KEZ40702.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 UPF0302 domain DUF3824 PF12868.2 KEZ40704.1 - 3.1e-05 24.9 27.5 0.00028 21.8 10.7 11.1 5 4 6 12 12 12 3 Domain of unknwon function (DUF3824) DUF4235 PF14019.1 KEZ40704.1 - 0.0047 16.7 7.3 1.5 8.7 0.0 4.1 3 1 0 3 3 3 2 Protein of unknown function (DUF4235) DUF4366 PF14283.1 KEZ40704.1 - 0.18 11.1 11.4 1.2 8.4 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4366) ABA_WDS PF02496.11 KEZ40704.1 - 0.43 10.7 31.6 0.037 14.1 1.3 5.3 4 2 1 5 5 5 0 ABA/WDS induced protein Gly-zipper_Omp PF13488.1 KEZ40704.1 - 1.4 8.5 17.9 0.45 10.1 0.1 3.6 4 0 0 4 4 4 0 Glycine zipper DnaJ PF00226.26 KEZ40705.1 - 1.1e-24 85.8 2.4 1.1e-24 85.8 1.7 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEZ40705.1 - 4.7e-15 55.3 13.7 7.5e-15 54.7 9.5 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KEZ40705.1 - 2.8e-11 43.1 0.0 5.3e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 KEZ40705.1 - 0.00019 21.0 4.5 0.019 14.6 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Integrase_Zn PF02022.14 KEZ40705.1 - 0.16 11.4 0.1 0.16 11.4 0.0 3.0 3 0 0 3 3 3 0 Integrase Zinc binding domain zf-TFIIB PF13453.1 KEZ40705.1 - 0.61 9.3 5.1 19 4.5 0.1 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-C3HC4_3 PF13920.1 KEZ40705.1 - 0.86 9.3 9.0 0.7 9.6 1.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Metallophos PF00149.23 KEZ40706.1 - 1.4e-09 37.6 3.4 4.9e-09 35.8 2.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEZ40706.1 - 0.00015 21.6 0.0 0.00035 20.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain OapA_N PF08525.6 KEZ40706.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif GAF_2 PF13185.1 KEZ40707.1 - 0.00014 22.3 0.0 0.00065 20.2 0.0 1.9 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 KEZ40707.1 - 0.011 15.8 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 0 GAF domain GAF PF01590.21 KEZ40707.1 - 0.023 14.8 0.0 0.029 14.5 0.0 1.3 1 1 0 1 1 1 0 GAF domain DLH PF01738.13 KEZ40708.1 - 2.4e-16 59.7 0.0 3e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ40708.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SCP2 PF02036.12 KEZ40709.1 - 2.9e-23 82.1 0.2 3.5e-23 81.8 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KEZ40709.1 - 0.00033 20.6 0.1 0.00046 20.1 0.1 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Glyco_hydro_72 PF03198.9 KEZ40710.1 - 5e-122 406.7 1.6 5.9e-122 406.5 1.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KEZ40710.1 - 3.2e-06 26.5 0.8 2.6e-05 23.5 0.5 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FCH PF00611.18 KEZ40711.1 - 1.8e-21 76.0 4.7 2.4e-21 75.7 0.0 3.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KEZ40711.1 - 6.5e-19 67.2 0.6 3.2e-11 42.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 KEZ40711.1 - 3.1e-14 52.4 5.3 4.8e-14 51.8 3.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 KEZ40711.1 - 1.4e-13 49.9 0.0 1.7e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KEZ40711.1 - 0.00021 20.7 0.1 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KEZ40711.1 - 0.00033 20.7 1.0 0.0063 16.6 0.2 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain Allexi_40kDa PF05549.6 KEZ40711.1 - 0.0013 18.0 4.7 0.0065 15.8 0.1 2.4 2 0 0 2 2 2 1 Allexivirus 40kDa protein Ax_dynein_light PF10211.4 KEZ40711.1 - 0.0091 15.8 5.6 0.0091 15.8 3.9 2.8 3 0 0 3 3 3 1 Axonemal dynein light chain DUF4482 PF14818.1 KEZ40711.1 - 0.021 15.4 3.4 0.021 15.4 2.4 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4482) C1_2 PF03107.11 KEZ40711.1 - 0.54 10.4 7.8 0.98 9.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain DEAD PF00270.24 KEZ40712.1 - 2.4e-34 118.2 0.1 5.1e-33 113.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ40712.1 - 2.4e-23 81.7 0.0 4.2e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEZ40712.1 - 0.062 13.4 1.4 0.94 9.6 0.8 2.9 3 1 0 3 3 3 0 AAA domain ResIII PF04851.10 KEZ40712.1 - 0.13 12.0 0.0 0.58 9.9 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CFEM PF05730.6 KEZ40713.1 - 0.03 14.1 7.4 0.057 13.2 5.1 1.5 1 0 0 1 1 1 0 CFEM domain DUF92 PF01940.11 KEZ40714.1 - 6e-64 215.2 2.5 8.2e-64 214.8 1.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Fungal_trans PF04082.13 KEZ40715.1 - 9.2e-10 37.8 3.2 2.7e-07 29.7 0.6 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short_C2 PF13561.1 KEZ40716.1 - 9.9e-28 97.5 0.0 1.4e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ40716.1 - 1.1e-27 96.9 0.3 1.5e-27 96.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ40716.1 - 9.4e-13 48.2 0.2 1.4e-12 47.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ40716.1 - 0.0037 16.7 0.0 0.0055 16.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 KEZ40716.1 - 0.016 15.0 0.3 0.032 14.0 0.1 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 KEZ40716.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KEZ40716.1 - 0.1 11.6 0.1 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ketoacyl-synt PF00109.21 KEZ40717.1 - 2.7e-70 236.7 0.0 4.7e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEZ40717.1 - 6.1e-50 170.3 0.0 4.2e-49 167.6 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.15 KEZ40717.1 - 2.2e-43 149.0 0.1 2.3e-42 145.8 0.0 2.5 3 0 0 3 3 3 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 KEZ40717.1 - 6.4e-36 122.8 0.7 6.4e-36 122.8 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KEZ40717.1 - 3.8e-23 81.5 4.9 2.6e-11 43.6 0.5 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KEZ40717.1 - 2.8e-14 52.9 0.0 7.1e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 KEZ40717.1 - 9.2e-06 25.6 1.1 0.0022 17.8 0.0 3.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ40717.1 - 3.1e-05 23.7 0.0 0.24 11.1 0.0 3.4 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KEZ40717.1 - 0.0011 18.0 0.2 0.0036 16.3 0.1 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cu-oxidase_3 PF07732.10 KEZ40718.1 - 6.1e-43 145.2 5.5 1.1e-39 134.8 0.1 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEZ40718.1 - 7.2e-41 138.9 12.6 2e-35 121.3 2.7 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KEZ40718.1 - 2.3e-21 76.3 0.1 2.4e-20 73.0 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 KEZ40718.1 - 0.038 13.8 0.0 3.9 7.4 0.0 3.2 3 0 0 3 3 3 0 Cupredoxin-like domain Glyco_transf_90 PF05686.7 KEZ40719.1 - 8.5e-21 74.0 0.0 1.3e-16 60.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 ArfGap PF01412.13 KEZ40720.1 - 1.8e-38 130.8 0.1 3.1e-38 130.1 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 KEZ40720.1 - 0.02 14.7 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain LETM1 PF07766.8 KEZ40721.1 - 1.1e-05 24.6 2.8 0.0097 14.9 0.9 2.1 2 0 0 2 2 2 2 LETM1-like protein Ran_BP1 PF00638.13 KEZ40722.1 - 1.1e-15 57.6 0.0 3.5e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 KEZ40722.1 - 9.1e-09 35.5 75.3 2.7e-06 27.5 25.6 10.8 2 1 5 9 9 9 6 Nucleoporin FG repeat region CaATP_NAI PF12515.3 KEZ40722.1 - 0.88 9.1 0.0 0.88 9.1 0.0 2.3 3 0 0 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain F_bP_aldolase PF01116.15 KEZ40723.1 - 1.2e-95 319.9 0.0 1.3e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CPSase_L_D2 PF02786.12 KEZ40723.1 - 0.17 11.1 0.5 0.29 10.3 0.4 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Tbf5 PF06331.7 KEZ40724.1 - 1.4e-25 88.8 1.3 1.6e-25 88.6 0.9 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 RrnaAD PF00398.15 KEZ40724.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ECH PF00378.15 KEZ40725.1 - 1.4e-40 139.0 1.1 4.3e-40 137.3 0.7 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KEZ40725.1 - 0.0032 17.6 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region HEAT_2 PF13646.1 KEZ40725.1 - 0.077 13.2 0.1 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats Aldo_ket_red PF00248.16 KEZ40726.1 - 4e-69 232.5 0.0 4.5e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.18 KEZ40727.1 - 2.6e-47 156.5 80.9 3.4e-07 29.8 1.1 9.4 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_4 PF14392.1 KEZ40727.1 - 6.4e-12 44.9 64.6 0.034 13.7 0.6 9.8 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_3 PF13917.1 KEZ40727.1 - 5.7e-06 25.9 62.2 0.016 14.9 0.4 8.7 3 3 6 9 9 9 7 Zinc knuckle zf-CCHC_2 PF13696.1 KEZ40727.1 - 0.0001 21.7 42.9 0.0056 16.1 0.2 7.6 8 1 1 9 9 9 5 Zinc knuckle PALP PF00291.20 KEZ40729.1 - 3.7e-20 72.3 0.0 4.6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sld5 PF05916.6 KEZ40733.1 - 2.6e-14 53.4 0.0 3.6e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.13 KEZ40734.1 - 1.7e-40 137.1 0.1 2.7e-40 136.4 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEZ40734.1 - 2.6e-31 107.7 1.7 4.5e-31 106.9 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 KEZ40734.1 - 0.46 9.5 2.4 0.84 8.7 0.0 2.5 3 1 0 3 3 3 0 Immunity protein 15 ASL_C2 PF14698.1 KEZ40735.1 - 1.1e-26 92.6 0.0 2.4e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal OPT PF03169.10 KEZ40736.1 - 3.4e-152 508.0 41.4 3.9e-152 507.8 28.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Abhydrolase_3 PF07859.8 KEZ40737.1 - 1.9e-32 112.5 0.0 5e-32 111.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 KEZ40737.1 - 2.4e-05 23.2 0.0 7.5e-05 21.6 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEZ40737.1 - 0.00052 19.7 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KEZ40737.1 - 0.0011 17.6 0.0 0.0015 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KEZ40737.1 - 0.004 16.3 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KEZ40737.1 - 0.0065 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 KEZ40737.1 - 0.012 14.8 0.5 0.019 14.1 0.3 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KEZ40737.1 - 0.012 15.4 1.3 0.023 14.5 0.9 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 KEZ40737.1 - 0.013 14.0 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.15 KEZ40737.1 - 0.064 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 KEZ40737.1 - 0.091 12.1 0.0 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Putative esterase SAPS PF04499.10 KEZ40738.1 - 3.9e-192 639.1 0.0 3.1e-190 632.8 0.0 3.2 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Peptidase_S8 PF00082.17 KEZ40739.1 - 7.5e-48 163.0 6.3 1.1e-47 162.5 4.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEZ40739.1 - 8.6e-13 48.6 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cyt-b5 PF00173.23 KEZ40740.1 - 3.4e-13 49.2 0.0 7.5e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 KEZ40740.1 - 3.6e-10 38.8 0.0 1.2e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.15 KEZ40740.1 - 4.9e-09 35.9 0.0 2.1e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KEZ40740.1 - 2.5e-08 34.4 0.0 7.6e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-LITAF-like PF10601.4 KEZ40741.1 - 7.7e-25 86.5 7.8 1.1e-24 86.0 5.4 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.1 KEZ40741.1 - 0.0023 17.0 2.1 1.2 8.4 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zf-TFIIB PF13453.1 KEZ40741.1 - 0.015 14.4 4.0 0.26 10.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger UPF0547 PF10571.4 KEZ40741.1 - 0.022 14.4 2.6 2.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DZR PF12773.2 KEZ40741.1 - 0.043 13.6 3.2 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 KEZ40741.1 - 0.046 13.1 0.2 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit TF_Zn_Ribbon PF08271.7 KEZ40741.1 - 0.052 12.8 0.7 6.8 6.0 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.1 KEZ40741.1 - 0.094 12.4 2.7 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KEZ40741.1 - 0.12 11.9 2.6 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KEZ40741.1 - 0.15 12.0 6.3 0.44 10.5 0.1 2.5 2 1 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.1 KEZ40741.1 - 0.16 12.0 2.7 7 6.7 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-HIT PF04438.11 KEZ40741.1 - 0.25 11.0 6.7 4.8 6.9 0.3 2.5 2 1 0 2 2 2 0 HIT zinc finger DUF329 PF03884.9 KEZ40741.1 - 0.25 10.9 1.9 13 5.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zinc_ribbon_2 PF13240.1 KEZ40741.1 - 0.37 10.3 4.4 4.1 7.0 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.6 KEZ40741.1 - 1.3 9.1 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-C3HC4_3 PF13920.1 KEZ40741.1 - 1.4 8.6 10.1 7.3 6.3 7.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEZ40741.1 - 1.5 8.7 10.1 0.4 10.5 3.9 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF2360 PF10152.4 KEZ40741.1 - 6.9 6.9 10.8 1.6 8.9 0.4 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) CLASP_N PF12348.3 KEZ40742.1 - 6.2e-06 25.7 0.0 0.00042 19.7 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal IncA PF04156.9 KEZ40742.1 - 0.00033 20.3 5.7 0.00096 18.7 4.0 1.8 1 0 0 1 1 1 1 IncA protein HEAT PF02985.17 KEZ40742.1 - 0.0012 18.7 0.3 2.4 8.4 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat HsbA PF12296.3 KEZ40742.1 - 0.019 14.8 1.6 0.26 11.1 0.1 3.2 3 0 0 3 3 3 0 Hydrophobic surface binding protein A DUF812 PF05667.6 KEZ40742.1 - 0.34 9.3 12.2 0.55 8.6 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_1 PF00170.16 KEZ40742.1 - 1.4 8.9 14.1 0.48 10.4 2.1 3.7 4 0 0 4 4 4 0 bZIP transcription factor APG6 PF04111.7 KEZ40742.1 - 2.5 7.0 12.2 4.7 6.1 8.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 KEZ40742.1 - 4.7 4.4 10.9 7.6 3.7 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.13 KEZ40742.1 - 6.1 6.6 13.5 2.5 7.8 3.0 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1162 PF06650.7 KEZ40743.1 - 2.4e-87 292.6 0.0 2.8e-85 285.8 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KEZ40743.1 - 5e-42 142.1 0.0 1.4e-41 140.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KEZ40743.1 - 3.7e-07 30.2 1.7 2.7e-06 27.4 0.0 3.0 3 0 0 3 3 3 1 ATG C terminal domain Nucleos_tra2_C PF07662.8 KEZ40744.1 - 1e-62 211.3 1.5 1e-62 211.3 1.1 2.5 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KEZ40744.1 - 1.2e-21 76.8 2.3 1.2e-21 76.8 1.6 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KEZ40744.1 - 0.031 14.1 16.7 0.047 13.5 5.9 3.4 2 1 0 2 2 2 0 Nucleoside recognition WSC PF01822.14 KEZ40745.1 - 1.3e-10 41.0 5.8 2.8e-10 39.9 4.0 1.5 1 0 0 1 1 1 1 WSC domain SBP56 PF05694.6 KEZ40746.1 - 3.2e-06 25.9 0.0 0.00023 19.8 0.0 2.5 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KEZ40746.1 - 0.073 12.1 0.0 6.2 5.8 0.0 2.4 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Nup160 PF11715.3 KEZ40746.1 - 0.12 10.4 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cupin_1 PF00190.17 KEZ40747.1 - 1.5e-29 102.2 0.0 2.5e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KEZ40747.1 - 1.1e-24 85.6 2.3 8.8e-14 50.7 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KEZ40747.1 - 4e-07 29.3 0.0 0.0019 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KEZ40747.1 - 3.6e-05 23.4 0.7 0.14 11.8 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 KEZ40747.1 - 0.00011 21.8 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_4 PF08007.7 KEZ40747.1 - 0.012 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein 2OG-FeII_Oxy_5 PF13759.1 KEZ40747.1 - 0.16 12.2 1.1 38 4.6 0.0 3.1 2 2 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase adh_short PF00106.20 KEZ40748.1 - 3e-22 79.3 0.1 4.2e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ40748.1 - 3.4e-12 46.6 0.0 4.5e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ40748.1 - 2.8e-11 43.4 0.1 7.7e-11 41.9 0.1 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KEZ40748.1 - 1.4e-05 24.1 0.5 3e-05 23.0 0.3 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEZ40748.1 - 0.00027 20.4 0.4 0.002 17.6 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KEZ40748.1 - 0.0015 18.6 0.1 0.0027 17.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KEZ40748.1 - 0.03 14.1 1.6 0.062 13.0 1.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 KEZ40748.1 - 0.033 14.6 1.7 0.089 13.2 0.6 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_1 PF00175.16 KEZ40749.1 - 3.6e-25 88.6 0.0 2.2e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEZ40749.1 - 1.5e-19 69.9 0.0 2.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEZ40749.1 - 1.1e-06 28.6 0.0 0.00061 19.7 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KEZ40749.1 - 0.0017 18.3 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Cyt-b5 PF00173.23 KEZ40750.1 - 2.5e-26 91.2 0.0 2.7e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2235 PF09994.4 KEZ40753.1 - 8.1e-44 150.0 0.0 1.7e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.18 KEZ40753.1 - 1.7e-08 34.4 0.0 3.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ40753.1 - 3.2e-05 23.1 0.0 6.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ40753.1 - 3.6e-05 23.9 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ40753.1 - 0.00046 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ40753.1 - 0.00049 20.1 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 KEZ40753.1 - 0.00077 19.1 0.0 0.0023 17.6 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KEZ40753.1 - 0.0012 19.3 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 KEZ40753.1 - 0.004 17.9 0.0 0.011 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEZ40753.1 - 0.0094 16.2 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Septin PF00735.13 KEZ40753.1 - 0.027 13.5 0.0 0.059 12.3 0.0 1.6 1 1 0 1 1 1 0 Septin AAA_33 PF13671.1 KEZ40753.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEZ40753.1 - 0.043 14.1 0.0 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEZ40753.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Dynamin_N PF00350.18 KEZ40753.1 - 0.056 13.2 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.9 KEZ40753.1 - 0.068 12.8 0.0 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KEZ40753.1 - 0.077 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AIG1 PF04548.11 KEZ40753.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_10 PF12846.2 KEZ40753.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 KEZ40753.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEZ40753.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 KEZ40753.1 - 0.17 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Gtr1_RagA PF04670.7 KEZ40753.1 - 0.23 10.5 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GST_C PF00043.20 KEZ40754.1 - 2.6e-08 33.7 0.1 4.2e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEZ40754.1 - 1.7e-06 27.9 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ40754.1 - 3.7e-06 27.0 0.0 9.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEZ40754.1 - 6.4e-05 23.0 0.0 0.0038 17.3 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ40754.1 - 0.00017 21.4 0.0 0.00038 20.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HNH_2 PF13391.1 KEZ40755.1 - 3.9e-09 36.1 0.1 7.5e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Translat_reg PF01818.12 KEZ40755.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage translational regulator DUF4360 PF14273.1 KEZ40756.1 - 1.4e-63 213.9 2.7 1.6e-63 213.7 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) NMO PF03060.10 KEZ40757.1 - 3.5e-45 154.5 1.5 1.4e-36 126.3 0.3 2.0 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KEZ40757.1 - 2.1e-08 33.4 2.1 0.0011 17.9 1.2 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEZ40757.1 - 1.6e-06 27.3 1.0 2.6e-06 26.6 0.7 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.13 KEZ40757.1 - 1.1e-05 24.4 1.6 1.6e-05 23.9 1.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KEZ40757.1 - 0.021 13.8 0.4 0.032 13.1 0.3 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase HRXXH PF13933.1 KEZ40758.1 - 3.9e-104 347.4 0.0 4.5e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.10 KEZ40758.1 - 0.0088 14.7 0.0 0.017 13.8 0.0 1.4 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Tyrosinase PF00264.15 KEZ40760.1 - 4.7e-29 102.1 0.2 7e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MIP PF00230.15 KEZ40760.1 - 1.3e-19 70.6 8.2 1.9e-19 70.0 5.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein UPRTase PF14681.1 KEZ40761.1 - 1.5e-19 70.0 0.0 2.6e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HAD PF12710.2 KEZ40761.1 - 4.5e-08 33.4 0.0 3.3e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 KEZ40761.1 - 0.00019 22.2 0.1 0.00084 20.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Hydrolase PF00702.21 KEZ40761.1 - 0.0021 18.4 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase KAP_NTPase PF07693.9 KEZ40761.1 - 0.024 13.6 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.1 KEZ40761.1 - 0.044 14.0 0.1 0.29 11.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KEZ40761.1 - 0.054 13.3 0.0 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain HET PF06985.6 KEZ40762.1 - 3.5e-13 49.8 6.0 3.5e-13 49.8 4.2 4.2 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2235 PF09994.4 KEZ40763.1 - 2e-63 214.3 0.0 2.7e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DPM3 PF08285.6 KEZ40763.1 - 1.1 9.1 6.9 0.19 11.6 0.9 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) An_peroxidase PF03098.10 KEZ40764.1 - 6.1e-67 226.1 0.0 7e-35 120.4 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.17 KEZ40764.1 - 6.9e-05 21.5 0.0 0.00069 18.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 NmrA PF05368.8 KEZ40765.1 - 1e-39 136.1 0.0 1.2e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ40765.1 - 2e-12 47.5 0.1 2.9e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEZ40765.1 - 2.2e-05 24.4 0.6 3.2e-05 23.9 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ40765.1 - 3.3e-05 23.6 0.2 4.7e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KEZ40765.1 - 7.2e-05 21.6 0.0 0.00011 20.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ40765.1 - 7.9e-05 22.1 0.1 0.00018 20.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEZ40765.1 - 0.011 14.6 0.1 0.021 13.7 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein NmrA PF05368.8 KEZ40766.1 - 1e-14 54.3 0.0 1.9e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ40766.1 - 3.4e-14 53.2 0.0 4.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEZ40766.1 - 0.00052 19.5 0.1 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KEZ40766.1 - 0.059 13.2 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KEZ40766.1 - 0.066 11.8 0.0 0.17 10.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEZ40766.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KEZ40767.1 - 2.6e-20 72.9 0.1 3.5e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ40767.1 - 2.3e-18 66.8 0.0 2.9e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ40767.1 - 0.00062 19.8 0.1 0.00095 19.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEZ40767.1 - 0.00088 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KEZ40767.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEZ40767.1 - 0.022 14.2 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PAE PF03283.8 KEZ40767.1 - 0.076 11.6 0.5 0.12 11.0 0.4 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Glyco_hydro_16 PF00722.16 KEZ40768.1 - 7.3e-34 116.6 0.5 7.3e-34 116.6 0.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.3 KEZ40768.1 - 0.0016 17.1 0.0 0.0024 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SSP160 PF06933.6 KEZ40768.1 - 1.3 6.9 14.0 1.9 6.3 9.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Metallophos PF00149.23 KEZ40769.1 - 8e-05 22.1 0.1 0.00013 21.4 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Nbs1_C PF08599.5 KEZ40769.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 COesterase PF00135.23 KEZ40770.1 - 6.6e-48 163.7 0.0 8.6e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ40770.1 - 3.7e-07 29.9 0.0 8.4e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ40770.1 - 0.0012 18.1 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ40770.1 - 0.031 14.0 0.0 0.061 13.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family AA_permease PF00324.16 KEZ40771.1 - 4.5e-99 331.9 35.4 5.4e-99 331.6 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ40771.1 - 1.6e-31 109.3 37.9 1.9e-31 109.0 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 KEZ40771.1 - 0.069 12.7 0.2 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Tbf5 PF06331.7 KEZ40772.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Galactosyl_T PF01762.16 KEZ40772.1 - 0.18 11.4 0.2 0.35 10.4 0.1 1.5 1 1 1 2 2 2 0 Galactosyltransferase FAD_binding_3 PF01494.14 KEZ40773.1 - 4.2e-19 68.8 0.0 7.1e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ40773.1 - 5.4e-05 22.2 0.0 6.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEZ40773.1 - 0.0018 17.4 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SE PF08491.5 KEZ40773.1 - 0.059 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.7 KEZ40773.1 - 0.067 12.1 0.0 0.2 10.5 0.0 1.8 2 1 0 2 2 2 0 Lycopene cyclase protein EthD PF07110.6 KEZ40774.1 - 1.2e-11 45.4 2.2 1.7e-11 44.8 1.5 1.3 1 0 0 1 1 1 1 EthD domain DUF805 PF05656.9 KEZ40774.1 - 0.032 14.0 0.7 0.032 14.0 0.5 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF805) DUF1625 PF07787.7 KEZ40775.1 - 0.034 13.4 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) SE PF08491.5 KEZ40778.1 - 2e-76 256.4 0.0 2.6e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KEZ40778.1 - 2e-13 50.0 0.0 2.6e-08 33.1 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEZ40778.1 - 8.6e-13 48.0 0.0 3.2e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ40778.1 - 5.6e-07 29.4 0.1 1.3e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ40778.1 - 1.6e-06 27.3 0.2 0.0026 16.7 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 KEZ40778.1 - 1.7e-06 27.2 0.0 5.3e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KEZ40778.1 - 8.3e-06 25.0 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ40778.1 - 2.8e-05 24.1 0.0 8e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ40778.1 - 5.5e-05 22.2 0.0 0.0056 15.5 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KEZ40778.1 - 0.0014 18.9 0.1 0.0042 17.4 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KEZ40778.1 - 0.0015 18.6 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KEZ40778.1 - 0.0028 16.7 0.6 0.0044 16.1 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GDI PF00996.13 KEZ40778.1 - 0.0036 15.6 0.0 0.0061 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor ThiF PF00899.16 KEZ40778.1 - 0.0097 15.7 0.2 0.019 14.7 0.2 1.5 1 0 0 1 1 1 1 ThiF family HI0933_like PF03486.9 KEZ40778.1 - 0.019 13.4 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.11 KEZ40778.1 - 0.019 14.3 0.2 0.04 13.3 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KEZ40778.1 - 0.037 14.4 0.1 0.09 13.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.9 KEZ40778.1 - 0.037 12.6 0.3 0.077 11.6 0.2 1.6 2 1 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 KEZ40778.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KEZ40778.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEZ40778.1 - 0.088 12.8 0.1 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.7 KEZ40779.1 - 1.8e-32 112.2 0.0 2.8e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KEZ40779.1 - 4e-15 55.1 0.0 1.5e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KEZ40779.1 - 4.6e-09 36.0 0.0 9.7e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KEZ40779.1 - 3.4e-05 23.8 0.0 0.0002 21.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 KEZ40779.1 - 4e-05 23.7 0.0 7.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 KEZ40779.1 - 0.0055 16.3 0.0 0.087 12.4 0.0 2.6 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 KEZ40779.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEZ40779.1 - 0.16 10.7 0.0 13 4.5 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Beta-lactamase PF00144.19 KEZ40780.1 - 3.5e-37 128.1 0.0 5.6e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 KEZ40781.1 - 1.9e-35 122.2 55.2 8.8e-34 116.7 35.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 KEZ40781.1 - 0.095 12.6 4.9 2.6 8.0 0.0 3.2 3 0 0 3 3 3 0 YtpI-like protein DUF3112 PF11309.3 KEZ40781.1 - 0.22 11.3 6.7 0.7 9.6 4.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) E1-E2_ATPase PF00122.15 KEZ40782.1 - 2.7e-45 154.2 5.2 5.3e-45 153.2 3.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ40782.1 - 2.2e-29 103.3 0.2 3.8e-29 102.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ40782.1 - 4.7e-13 49.7 0.0 2.1e-12 47.6 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEZ40782.1 - 4e-05 23.6 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KEZ40782.1 - 0.0058 16.2 0.0 0.038 13.5 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEZ40782.1 - 0.23 10.7 0.0 0.85 8.8 0.0 1.9 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DUF1264 PF06884.6 KEZ40783.1 - 2.9e-44 150.5 0.4 3.3e-44 150.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Methyltransf_23 PF13489.1 KEZ40784.1 - 2e-16 60.1 0.0 3e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40784.1 - 2e-10 41.2 0.0 2.2e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ40784.1 - 7.7e-05 23.1 0.0 0.00018 21.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40784.1 - 8.5e-05 22.1 0.0 0.00023 20.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40784.1 - 0.00022 21.6 0.0 0.00062 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ40784.1 - 0.00071 18.7 0.0 0.0069 15.5 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ40784.1 - 0.0011 19.2 0.0 0.0042 17.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ40784.1 - 0.0045 16.0 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 KEZ40784.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 KEZ40784.1 - 0.031 14.2 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEZ40784.1 - 0.083 12.2 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.5 KEZ40784.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_20 PF12147.3 KEZ40784.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 KEZ40785.1 - 1.9e-73 247.5 0.0 2.6e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 KEZ40786.1 - 1.8e-06 27.4 0.0 2.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Cutinase PF01083.17 KEZ40788.1 - 4.9e-34 117.6 2.8 5.8e-34 117.3 1.9 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KEZ40788.1 - 0.042 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain FAD_binding_3 PF01494.14 KEZ40789.1 - 1.7e-74 251.0 0.0 2.1e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ40789.1 - 8.3e-11 41.3 0.0 2.5e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ40789.1 - 4.9e-06 26.8 0.0 0.027 14.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ40789.1 - 6.2e-05 23.1 0.0 0.00029 20.9 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ40789.1 - 6.2e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KEZ40789.1 - 0.00025 21.0 0.0 0.0011 18.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ40789.1 - 0.00028 19.9 0.0 0.0039 16.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ40789.1 - 0.00034 20.5 0.0 0.00096 19.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ40789.1 - 0.00038 19.4 0.0 0.00079 18.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ40789.1 - 0.00081 17.9 0.0 0.011 14.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KEZ40789.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ40789.1 - 0.042 13.6 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KEZ40789.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF2251 PF10008.4 KEZ40789.1 - 0.084 13.0 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) Cupin_5 PF06172.6 KEZ40791.1 - 4e-35 120.7 0.0 4.7e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) DUF2422 PF10337.4 KEZ40792.1 - 6.7e-102 341.6 0.6 7.3e-100 334.9 0.4 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KEZ40792.1 - 7.8e-62 208.8 0.0 4.1e-61 206.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KEZ40792.1 - 8.8e-09 35.3 14.5 8.8e-09 35.3 10.1 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KEZ40792.1 - 0.007 15.0 1.8 0.01 14.4 0.3 2.0 3 0 0 3 3 3 1 Aluminium activated malate transporter Oxidored_FMN PF00724.15 KEZ40793.1 - 8.4e-52 176.2 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 KEZ40793.1 - 0.13 11.0 0.1 0.39 9.5 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TPR_11 PF13414.1 KEZ40794.1 - 3.7e-15 55.3 14.5 3.3e-05 23.4 0.2 4.7 4 0 0 4 4 4 4 TPR repeat TPR_12 PF13424.1 KEZ40794.1 - 4.4e-12 45.7 9.6 3e-10 39.9 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ40794.1 - 1.1e-11 43.7 12.3 0.00044 19.9 0.3 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ40794.1 - 3.2e-09 37.2 7.2 0.0075 16.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ40794.1 - 4.2e-08 33.1 9.5 0.00029 21.1 0.3 6.2 4 1 2 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ40794.1 - 3.5e-05 23.2 8.4 0.006 16.2 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KEZ40794.1 - 8e-05 22.7 5.3 0.18 11.9 0.0 4.5 3 1 2 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEZ40794.1 - 0.00011 21.7 4.1 0.01 15.5 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ40794.1 - 0.00029 20.2 10.1 0.67 9.6 0.3 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ40794.1 - 0.00049 20.0 5.6 0.94 9.8 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Sec34 PF04136.10 KEZ40794.1 - 0.0013 18.4 0.3 0.0089 15.7 0.0 2.6 2 0 0 2 2 2 1 Sec34-like family TPR_20 PF14561.1 KEZ40794.1 - 0.0075 16.3 1.9 0.75 9.9 0.4 4.1 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ40794.1 - 0.023 15.1 8.0 1.6 9.3 0.3 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 KEZ40794.1 - 0.028 14.4 0.6 0.39 10.6 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain TPR_19 PF14559.1 KEZ40794.1 - 0.029 14.7 15.3 0.42 10.9 1.5 5.0 3 1 2 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.1 KEZ40794.1 - 0.038 14.1 0.0 0.34 11.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF1996 PF09362.5 KEZ40795.1 - 8.4e-52 176.1 0.0 1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) 4HBT_2 PF13279.1 KEZ40796.1 - 3.2e-05 24.3 0.0 5.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Cas_Csy4 PF09618.5 KEZ40797.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Isochorismatase PF00857.15 KEZ40798.1 - 5.3e-16 59.0 0.0 8.7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Acetyltransf_3 PF13302.1 KEZ40799.1 - 5.1e-11 42.9 0.0 8.2e-11 42.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2236 PF09995.4 KEZ40799.1 - 0.035 13.4 0.6 0.15 11.3 0.3 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) Zn_clus PF00172.13 KEZ40800.1 - 5.3e-10 39.0 8.0 5.3e-10 39.0 5.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASFV_J13L PF05568.6 KEZ40801.1 - 0.0052 16.3 0.1 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 African swine fever virus J13L protein Pyr_redox_2 PF07992.9 KEZ40803.1 - 1.5e-14 54.3 0.0 2.9e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ40803.1 - 5.2e-10 39.6 2.4 6.4e-08 32.8 0.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ40803.1 - 2.4e-08 34.3 2.9 0.00056 20.0 0.1 3.2 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ40803.1 - 4.3e-08 32.4 0.1 6.1e-06 25.3 0.0 2.3 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ40803.1 - 0.00019 21.2 4.8 0.26 11.0 0.0 3.4 3 1 1 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.13 KEZ40803.1 - 0.0036 17.3 0.3 0.18 11.8 0.1 2.6 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 KEZ40803.1 - 0.014 14.3 2.1 0.032 13.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3236 PF11576.3 KEZ40803.1 - 0.02 14.3 0.1 0.36 10.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3236) Shikimate_DH PF01488.15 KEZ40803.1 - 0.055 13.5 1.9 4.5 7.3 0.0 2.7 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KEZ40803.1 - 0.18 10.7 8.9 0.84 8.4 0.1 3.4 3 1 1 4 4 4 0 FAD dependent oxidoreductase NACHT PF05729.7 KEZ40804.1 - 6.8e-07 29.0 0.1 5.3e-06 26.1 0.1 2.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ40804.1 - 7.8e-05 22.8 0.0 0.00038 20.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEZ40804.1 - 0.0019 17.7 2.4 0.0086 15.5 0.0 3.0 4 0 0 4 4 4 1 AAA-like domain AAA_17 PF13207.1 KEZ40804.1 - 0.0062 17.3 0.0 0.032 15.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEZ40804.1 - 0.022 15.0 0.1 0.34 11.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 KEZ40804.1 - 0.036 14.3 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ40804.1 - 0.04 13.4 0.7 0.09 12.3 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hpt PF01627.18 KEZ40804.1 - 0.054 13.4 0.1 0.054 13.4 0.0 3.4 4 0 0 4 4 4 0 Hpt domain RNA_helicase PF00910.17 KEZ40804.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 KEZ40804.1 - 0.19 11.2 0.1 0.62 9.5 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 KEZ40804.1 - 0.24 11.6 2.3 0.34 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KEZ40804.1 - 1.5 7.7 3.9 1.5 7.6 0.0 2.7 3 1 1 4 4 4 0 KAP family P-loop domain adh_short PF00106.20 KEZ40805.1 - 5e-26 91.5 2.3 7.1e-26 91.1 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ40805.1 - 3.8e-16 59.5 0.0 4.5e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ40805.1 - 1.4e-09 37.8 1.3 2e-09 37.3 0.9 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KEZ40805.1 - 0.0013 18.4 0.3 0.0024 17.5 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KEZ40805.1 - 0.032 13.3 0.5 0.08 12.0 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KEZ40805.1 - 0.054 13.5 1.4 0.17 11.8 0.8 2.0 1 1 1 2 2 2 0 NADH(P)-binding Methyltransf_12 PF08242.7 KEZ40805.1 - 0.1 13.0 0.1 0.57 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KEZ40805.1 - 0.13 11.6 0.4 0.23 10.8 0.1 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldedh PF00171.17 KEZ40806.1 - 3.4e-134 447.6 0.0 4.2e-134 447.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ40806.1 - 2.6e-06 26.4 0.0 8e-06 24.8 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KEZ40806.1 - 0.0083 15.3 0.0 0.063 12.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Fungal_trans_2 PF11951.3 KEZ40807.1 - 1.9e-38 132.0 1.1 2.8e-38 131.5 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40807.1 - 4.8e-08 32.7 12.8 8.2e-08 32.0 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gln-synt_C PF00120.19 KEZ40808.1 - 1.3e-49 168.7 0.0 1.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain H_lectin PF09458.5 KEZ40809.1 - 2.4e-18 65.5 0.1 1.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 H-type lectin domain Peptidase_S8 PF00082.17 KEZ40809.1 - 4.7e-06 25.9 0.0 9.9e-06 24.8 0.0 1.7 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.11 KEZ40813.1 - 1.1e-32 113.2 29.7 5.7e-32 110.8 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ40813.1 - 1.3e-05 23.7 12.0 1.3e-05 23.7 8.3 1.5 2 0 0 2 2 2 1 MFS/sugar transport protein ESSS PF10183.4 KEZ40813.1 - 0.25 11.7 1.4 0.62 10.4 0.7 1.9 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ASFV_J13L PF05568.6 KEZ40814.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4079 PF13301.1 KEZ40814.1 - 0.31 11.0 5.7 0.085 12.8 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2975 PF11188.3 KEZ40814.1 - 6.6 6.4 14.7 0.55 9.9 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) FAD_binding_3 PF01494.14 KEZ40815.1 - 1.6e-16 60.2 0.1 1e-09 37.9 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEZ40815.1 - 3.1e-05 23.9 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ40815.1 - 0.00048 19.1 0.2 0.2 10.5 0.0 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ40815.1 - 0.0093 16.3 0.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ40815.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ40815.1 - 0.12 12.1 0.1 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KEZ40815.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.20 KEZ40816.1 - 8.5e-24 84.0 0.0 1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ40816.1 - 6.8e-14 51.5 0.0 8.4e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MMR_HSR1 PF01926.18 KEZ40817.1 - 1.8e-11 43.9 0.0 2.2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEZ40817.1 - 1.4e-07 30.8 0.0 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 KEZ40817.1 - 1.4e-07 31.4 1.0 0.011 15.6 0.1 2.1 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.13 KEZ40817.1 - 3.5e-07 29.6 0.0 4.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KEZ40817.1 - 1.5e-05 24.2 0.4 4e-05 22.8 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KEZ40817.1 - 0.00033 21.1 0.0 0.00042 20.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 KEZ40817.1 - 0.0016 18.0 1.8 0.037 13.5 0.5 2.0 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.13 KEZ40817.1 - 0.0019 17.2 0.4 0.0037 16.3 0.3 1.5 1 1 0 1 1 1 1 Septin NB-ARC PF00931.17 KEZ40817.1 - 0.003 16.4 0.2 0.0045 15.8 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain SRPRB PF09439.5 KEZ40817.1 - 0.0035 16.5 0.0 0.0043 16.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KEZ40817.1 - 0.0072 16.6 0.4 0.0098 16.1 0.3 1.3 1 1 0 1 1 1 1 ABC transporter MobB PF03205.9 KEZ40817.1 - 0.01 15.5 0.3 0.014 15.0 0.2 1.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 KEZ40817.1 - 0.01 14.6 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.16 KEZ40817.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_17 PF13207.1 KEZ40817.1 - 0.017 15.9 0.2 0.025 15.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KEZ40817.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KEZ40817.1 - 0.021 14.7 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KEZ40817.1 - 0.032 13.7 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 KEZ40817.1 - 0.036 12.8 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 KEZ40817.1 - 0.04 13.4 0.4 0.064 12.8 0.2 1.3 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KEZ40817.1 - 0.06 12.7 3.5 0.31 10.4 1.2 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KEZ40817.1 - 0.072 12.7 0.2 0.084 12.5 0.1 1.4 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KEZ40817.1 - 0.082 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 KEZ40817.1 - 0.082 13.0 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KEZ40817.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Gtr1_RagA PF04670.7 KEZ40817.1 - 0.088 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEZ40817.1 - 0.097 12.1 2.2 2.4 7.5 1.5 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KEZ40817.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 KEZ40817.1 - 0.12 11.2 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.4 KEZ40817.1 - 0.14 11.5 0.7 0.31 10.5 0.5 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 KEZ40817.1 - 0.16 12.3 0.5 0.19 12.0 0.4 1.3 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.23 KEZ40819.1 - 4.2e-81 272.4 0.0 7.3e-81 271.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KEZ40819.1 - 3.2e-76 256.1 0.1 1.5e-75 253.9 0.0 2.3 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 KEZ40819.1 - 1.5e-53 181.6 0.2 4.1e-53 180.1 0.0 1.8 2 0 0 2 2 2 1 Condensation domain KR PF08659.5 KEZ40819.1 - 1.7e-51 174.4 1.2 6.4e-51 172.5 0.0 2.7 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 KEZ40819.1 - 4.2e-48 164.0 0.0 1e-47 162.7 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEZ40819.1 - 2.7e-44 151.0 3.3 3.6e-43 147.3 0.0 3.6 4 0 0 4 4 2 1 short chain dehydrogenase Acyl_transf_1 PF00698.16 KEZ40819.1 - 7.1e-38 130.7 0.5 6.6e-35 120.9 0.3 2.5 1 1 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 KEZ40819.1 - 1.3e-32 112.6 0.0 3.4e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KEZ40819.1 - 9.2e-23 80.2 0.4 8.1e-11 42.0 0.0 3.9 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEZ40819.1 - 1.9e-19 69.9 0.0 7e-19 68.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 KEZ40819.1 - 1.2e-14 54.1 0.0 1.4e-13 50.7 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 KEZ40819.1 - 1.3e-14 54.2 0.0 4e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 KEZ40819.1 - 2.9e-14 53.0 0.0 6.2e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40819.1 - 3.9e-13 49.2 0.0 1.4e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40819.1 - 3.4e-10 40.4 0.0 2e-09 38.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KEZ40819.1 - 3.7e-10 39.9 0.0 1.8e-09 37.7 0.0 2.3 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 KEZ40819.1 - 6.9e-10 39.2 0.0 2.2e-09 37.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KEZ40819.1 - 8.1e-08 31.2 0.0 4.7e-06 25.5 0.0 2.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KEZ40819.1 - 1.1e-07 31.2 0.0 8.4e-06 25.0 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KEZ40819.1 - 7.5e-05 21.8 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KEZ40819.1 - 0.00011 21.7 0.0 0.00032 20.2 0.0 1.7 2 0 0 2 2 1 1 Putative methyltransferase PCMT PF01135.14 KEZ40819.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KEZ40819.1 - 0.0027 17.0 0.0 0.0069 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 KEZ40819.1 - 0.009 15.4 0.0 0.025 13.9 0.0 1.7 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.7 KEZ40819.1 - 0.032 13.0 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase GFO_IDH_MocA PF01408.17 KEZ40820.1 - 1.1e-20 74.2 0.0 2e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KEZ40820.1 - 6.4e-06 26.4 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 KEZ40821.1 - 1e-17 63.9 5.1 3.1e-17 62.3 2.6 2.4 2 1 0 2 2 2 1 FAD binding domain Polyketide_cyc2 PF10604.4 KEZ40821.1 - 0.029 14.5 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_3 PF01494.14 KEZ40822.1 - 2.7e-22 79.3 0.1 6.7e-14 51.7 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ40822.1 - 2.2e-07 30.1 0.0 0.008 15.1 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ40822.1 - 5e-06 26.4 0.1 1.9e-05 24.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ40822.1 - 8e-06 26.1 0.0 0.0083 16.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ40822.1 - 0.0028 17.5 0.0 0.005 16.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ40822.1 - 0.0034 16.5 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KEZ40822.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KEZ40822.1 - 0.013 14.4 0.0 0.064 12.1 0.0 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 KEZ40822.1 - 0.022 13.8 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KEZ40822.1 - 0.026 13.1 0.0 18 3.8 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KEZ40822.1 - 0.039 13.7 0.1 7.9 6.2 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KEZ40822.1 - 0.12 12.4 0.0 0.35 10.8 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ40822.1 - 0.15 10.4 0.0 3.4 6.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.5 KEZ40822.1 - 0.21 10.3 0.0 0.39 9.4 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase Anoctamin PF04547.7 KEZ40823.1 - 1.5e-105 353.5 5.6 1.8e-105 353.2 3.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel FA_desaturase PF00487.19 KEZ40823.1 - 5.2 6.4 9.2 6.1 6.2 1.5 2.9 3 0 0 3 3 3 0 Fatty acid desaturase ADH_zinc_N PF00107.21 KEZ40824.1 - 3.2e-10 39.6 0.0 5.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ40824.1 - 3.3e-05 23.5 0.0 7.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KEZ40825.1 - 3.5e-81 273.0 0.0 4.5e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KEZ40825.1 - 6e-26 91.2 0.0 1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEZ40825.1 - 1.6e-14 54.1 0.0 3.4e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEZ40825.1 - 4.8e-14 52.8 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DIOX_N PF14226.1 KEZ40826.1 - 4.9e-26 91.5 0.0 8.2e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEZ40826.1 - 4e-17 62.3 0.0 6.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AhpC-TSA_2 PF13911.1 KEZ40827.1 - 6e-13 48.7 0.0 9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KEZ40827.1 - 0.0002 21.0 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KEZ40827.1 - 0.0053 16.3 0.0 0.18 11.3 0.0 2.2 1 1 0 1 1 1 1 Redoxin DUF2665 PF11654.3 KEZ40828.1 - 0.12 11.9 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DUF1517 PF07466.6 KEZ40828.1 - 0.49 9.3 5.6 0.5 9.3 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) DUF605 PF04652.11 KEZ40828.1 - 0.54 9.5 5.4 0.73 9.1 3.7 1.1 1 0 0 1 1 1 0 Vta1 like SSP160 PF06933.6 KEZ40828.1 - 1.2 7.0 11.5 1.5 6.6 8.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.6 KEZ40828.1 - 4.4 7.3 10.9 6.4 6.8 7.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FR47 PF08445.5 KEZ40829.1 - 2.8e-05 23.7 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KEZ40829.1 - 3.3e-05 23.9 0.0 8.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEZ40829.1 - 0.0061 16.5 0.0 0.02 14.8 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KEZ40829.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC2_membrane PF01061.19 KEZ40831.1 - 1e-72 243.7 53.0 2.7e-38 131.2 15.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEZ40831.1 - 6.5e-35 120.4 0.0 1.7e-17 64.0 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KEZ40831.1 - 5e-33 112.8 0.8 2.9e-27 94.3 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 KEZ40831.1 - 1.2e-14 54.1 0.0 2.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEZ40831.1 - 9.2e-08 31.7 0.0 0.00022 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KEZ40831.1 - 1.4e-07 30.8 35.9 0.00096 18.2 9.2 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 KEZ40831.1 - 2.1e-06 27.0 0.1 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ40831.1 - 0.00022 22.0 0.0 0.3 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ40831.1 - 0.00022 20.6 0.4 0.029 13.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 KEZ40831.1 - 0.00023 20.4 0.0 0.084 12.0 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KEZ40831.1 - 0.00039 20.4 0.3 0.058 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KEZ40831.1 - 0.00043 20.1 0.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEZ40831.1 - 0.0017 18.5 0.2 1.2 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KEZ40831.1 - 0.003 17.5 0.0 1.5 8.7 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 KEZ40831.1 - 0.0066 16.7 0.1 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEZ40831.1 - 0.0068 16.6 0.3 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEZ40831.1 - 0.0087 15.7 0.1 2.8 7.7 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KEZ40831.1 - 0.017 14.8 1.2 2.2 7.8 0.3 2.8 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 KEZ40831.1 - 0.017 14.5 0.3 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KEZ40831.1 - 0.036 13.6 0.1 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEZ40831.1 - 0.11 12.4 0.4 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KEZ40831.1 - 0.12 12.0 0.5 4.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KEZ40831.1 - 0.15 11.5 1.7 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 KEZ40831.1 - 0.16 12.3 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3314 PF11771.3 KEZ40832.1 - 0.0029 17.3 0.1 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3314) NACHT PF05729.7 KEZ40833.1 - 3.1e-10 39.9 0.1 9.1e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ40833.1 - 1.6e-08 34.7 0.0 1.1e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ40833.1 - 3.6e-07 30.3 0.2 6.1e-06 26.3 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KEZ40833.1 - 0.0015 18.0 0.0 0.0043 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 KEZ40833.1 - 0.005 17.6 0.2 0.018 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KEZ40833.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEZ40833.1 - 0.021 14.9 0.0 0.07 13.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.1 KEZ40833.1 - 0.024 14.9 0.0 0.085 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEZ40833.1 - 0.025 14.4 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEZ40833.1 - 0.055 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KEZ40833.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 KEZ40833.1 - 0.1 12.9 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 KEZ40833.1 - 0.13 12.2 0.0 1 9.3 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain CFEM PF05730.6 KEZ40834.1 - 0.0045 16.7 8.1 0.0054 16.5 5.6 1.2 1 0 0 1 1 1 1 CFEM domain Nckap1 PF09735.4 KEZ40834.1 - 0.031 11.7 0.8 0.036 11.5 0.5 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Gly_transf_sug PF04488.10 KEZ40835.1 - 5.3e-15 55.6 0.1 9.9e-14 51.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KEZ40835.1 - 0.017 13.6 0.1 0.033 12.6 0.1 1.4 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain SKG6 PF08693.5 KEZ40836.1 - 0.0017 17.6 3.8 0.0033 16.6 2.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 KEZ40836.1 - 0.0024 17.4 0.1 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Podoplanin VSP PF03302.8 KEZ40836.1 - 0.08 11.5 0.2 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM51 PF15345.1 KEZ40836.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Gram_pos_anchor PF00746.16 KEZ40836.1 - 0.22 11.3 4.0 0.41 10.5 2.8 1.5 1 0 0 1 1 1 0 Gram positive anchor VPEP PF07589.6 KEZ40836.1 - 2.3 8.2 4.4 4.7 7.2 3.1 1.6 1 0 0 1 1 1 0 PEP-CTERM motif GFO_IDH_MocA PF01408.17 KEZ40838.1 - 1.4e-15 57.8 0.0 2.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KEZ40838.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Pyridoxal_deC PF00282.14 KEZ40839.1 - 5.6e-27 94.1 0.0 8.9e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KEZ40839.1 - 2.1e-05 23.8 0.0 2.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase adh_short_C2 PF13561.1 KEZ40840.1 - 1.3e-32 113.4 0.1 1.5e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ40840.1 - 2.4e-29 102.4 0.2 2.9e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ40840.1 - 4.8e-16 58.9 0.1 6.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NusB PF01029.13 KEZ40840.1 - 0.029 14.3 0.1 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 NusB family Peptidase_C97 PF05903.9 KEZ40841.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KEZ40841.1 - 0.0061 16.5 0.3 0.033 14.1 0.1 2.0 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DUF1870 PF08965.5 KEZ40841.1 - 0.085 12.5 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) HET PF06985.6 KEZ40842.1 - 2.2e-34 118.6 0.1 3.3e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEZ40842.1 - 4.5e-33 114.4 52.3 8.4e-33 113.5 36.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40842.1 - 6.6e-14 51.3 12.8 6.6e-14 51.3 8.9 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Pam17 PF08566.5 KEZ40842.1 - 0.032 13.9 1.4 0.16 11.6 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Esterase_phd PF10503.4 KEZ40843.1 - 2.5e-21 75.9 0.1 3.3e-21 75.5 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEZ40843.1 - 2.3e-12 46.6 0.8 3.3e-12 46.0 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 KEZ40843.1 - 8.1e-07 28.1 0.1 1.1e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEZ40843.1 - 8.4e-05 22.3 0.1 0.00011 21.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ40843.1 - 0.00035 20.5 0.0 0.00073 19.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ40843.1 - 0.00036 20.1 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold FA_desaturase PF00487.19 KEZ40844.1 - 1.6e-24 86.7 29.0 3.9e-24 85.5 20.1 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KEZ40844.1 - 1.2e-05 25.3 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF1349 PF07081.6 KEZ40845.1 - 4.2e-14 52.3 0.0 7.6e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Aldedh PF00171.17 KEZ40846.1 - 6.7e-144 479.6 1.0 2.8e-116 388.6 0.5 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Zn_clus PF00172.13 KEZ40847.1 - 7.4e-08 32.1 10.4 1.2e-07 31.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UbiD PF01977.11 KEZ40848.1 - 2.4e-113 378.6 0.0 3.6e-113 378.0 0.0 1.2 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase TPP_enzyme_N PF02776.13 KEZ40849.1 - 2.7e-33 114.8 0.3 5.4e-32 110.6 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ40849.1 - 1.2e-19 70.4 0.0 3.2e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KEZ40849.1 - 1.5e-13 50.5 0.1 3.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.11 KEZ40850.1 - 2.6e-29 102.0 29.8 9.9e-29 100.1 20.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Cu_amine_oxid PF01179.15 KEZ40851.1 - 1.3e-117 393.0 0.0 9.9e-95 317.6 0.0 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KEZ40851.1 - 5.1e-09 36.0 0.3 5.1e-09 36.0 0.2 2.2 3 0 0 3 3 3 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KEZ40851.1 - 4e-06 26.8 0.0 1.7e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain FAD_binding_4 PF01565.18 KEZ40852.1 - 6.9e-21 74.1 0.2 1e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Frataxin_Cyay PF01491.11 KEZ40852.1 - 0.077 12.7 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Frataxin-like domain AA_permease_2 PF13520.1 KEZ40853.1 - 6.2e-54 183.1 30.8 8.3e-54 182.7 21.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ40853.1 - 2.2e-22 79.0 26.8 2.8e-22 78.7 18.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3483 PF11982.3 KEZ40853.1 - 2.7 7.2 10.6 0.053 12.8 1.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3483) FMN_dh PF01070.13 KEZ40854.1 - 3e-106 355.2 0.5 3.7e-106 354.9 0.4 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEZ40854.1 - 9e-17 60.6 0.0 1.9e-10 40.3 0.0 2.6 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KEZ40854.1 - 2.4e-06 26.7 0.1 4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEZ40854.1 - 0.0014 17.6 0.9 0.0022 16.9 0.1 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KEZ40854.1 - 0.0023 17.1 4.2 0.0043 16.2 1.1 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 KEZ40854.1 - 0.0086 15.1 1.8 0.63 9.0 0.1 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Aldedh PF00171.17 KEZ40855.1 - 1.2e-130 436.0 0.1 1.5e-130 435.6 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEZ40855.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) ATP-synt_C PF00137.16 KEZ40856.1 - 1.8e-17 62.9 12.2 3.3e-17 62.1 8.5 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DNAPolymera_Pol PF11590.3 KEZ40856.1 - 0.05 13.2 0.5 0.12 12.0 0.3 1.7 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol ketoacyl-synt PF00109.21 KEZ40857.1 - 1.6e-55 188.3 0.1 3.3e-55 187.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEZ40857.1 - 2.9e-50 170.4 0.2 8.7e-50 168.8 0.1 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KEZ40857.1 - 4.3e-38 131.4 0.0 2.3e-23 83.0 0.0 2.5 1 1 1 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 KEZ40857.1 - 5.4e-38 130.8 0.1 1e-37 129.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEZ40857.1 - 2.4e-35 121.9 0.7 1.1e-34 119.7 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEZ40857.1 - 7.9e-24 83.7 0.0 2e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEZ40857.1 - 2.3e-16 59.5 0.0 1.1e-15 57.2 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KEZ40857.1 - 8.7e-16 58.2 0.0 2.2e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ40857.1 - 7.7e-12 45.2 0.0 7.5e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40857.1 - 2.6e-10 40.0 0.0 5.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40857.1 - 3.2e-10 40.3 0.0 1.4e-09 38.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KEZ40857.1 - 7.1e-08 32.5 0.0 2.3e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KEZ40857.1 - 1.1e-07 32.4 0.0 3.4e-06 27.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ40857.1 - 0.00045 20.2 0.0 0.002 18.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.5 KEZ40857.1 - 0.00069 19.2 0.3 0.0019 17.8 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KEZ40857.1 - 0.0012 17.9 0.1 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 KEZ40857.1 - 0.0015 17.7 0.0 0.0035 16.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEZ40857.1 - 0.002 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.12 KEZ40857.1 - 0.04 13.3 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NmrA PF05368.8 KEZ40857.1 - 0.26 10.5 0.0 0.62 9.2 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family Aldedh PF00171.17 KEZ40859.1 - 1.5e-173 577.3 0.0 2.1e-173 576.9 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.3 KEZ40860.1 - 2.5e-21 75.7 0.2 4.2e-21 75.0 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40860.1 - 4.1e-10 39.4 8.7 8.7e-10 38.3 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.15 KEZ40861.1 - 7e-165 548.7 0.0 8.6e-165 548.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KEZ40861.1 - 2.9e-22 78.6 0.0 6.8e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KEZ40861.1 - 3.9e-15 55.6 0.0 8.1e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AAA PF00004.24 KEZ40862.1 - 3.6e-08 33.6 0.2 3e-07 30.7 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ40862.1 - 3.2e-05 24.0 0.1 0.00038 20.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ40862.1 - 0.00084 20.1 0.0 0.0025 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ40862.1 - 0.001 19.0 0.0 0.003 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 KEZ40862.1 - 0.0012 17.6 0.1 0.0084 14.8 0.0 2.2 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KEZ40862.1 - 0.0059 16.4 0.0 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ40862.1 - 0.015 15.0 0.0 0.05 13.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KEZ40862.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KEZ40862.1 - 0.041 12.5 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 KEZ40862.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RuvB_N PF05496.7 KEZ40862.1 - 0.092 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KEZ40862.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PTCB-BRCT PF12738.2 KEZ40865.1 - 3e-41 139.1 0.2 1.1e-20 73.1 0.0 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KEZ40865.1 - 5.5e-36 122.5 0.0 5.1e-13 48.9 0.0 4.5 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain OHCU_decarbox PF09349.5 KEZ40866.1 - 6.1e-41 140.3 0.0 7.1e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.6 KEZ40867.1 - 1.5e-27 95.0 0.6 1.5e-27 95.0 0.4 1.9 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 KEZ40867.1 - 1.2e-14 53.4 0.2 0.00016 21.4 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 KEZ40867.1 - 9.8e-06 25.4 0.0 0.00074 19.2 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A U-box PF04564.10 KEZ40867.1 - 0.005 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KEZ40867.1 - 0.0076 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CheZ PF04344.8 KEZ40867.1 - 0.051 13.2 0.3 0.076 12.6 0.2 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ VID27 PF08553.5 KEZ40867.1 - 0.066 11.4 0.1 0.16 10.1 0.0 1.6 2 0 0 2 2 2 0 VID27 cytoplasmic protein DUF3312 PF11768.3 KEZ40867.1 - 0.16 10.1 0.0 0.35 9.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) zf-RING_5 PF14634.1 KEZ40868.1 - 0.022 14.4 6.4 0.075 12.7 4.4 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEZ40868.1 - 0.026 14.3 1.7 0.056 13.3 0.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KEZ40868.1 - 0.042 13.3 0.5 0.042 13.3 0.4 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 KEZ40868.1 - 0.063 13.3 1.0 0.063 13.3 0.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ40868.1 - 0.1 12.4 2.4 0.15 11.9 0.4 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 KEZ40868.1 - 0.21 11.2 2.8 0.57 9.8 2.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RPAP2_Rtr1 PF04181.8 KEZ40868.1 - 0.79 9.8 3.2 0.85 9.7 1.2 1.7 2 0 0 2 2 2 0 Rtr1/RPAP2 family zf-UDP PF14569.1 KEZ40868.1 - 2.6 7.8 5.1 9.1 6.1 0.5 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger TraQ PF09679.5 KEZ40869.1 - 0.044 13.7 0.1 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Aldo_ket_red PF00248.16 KEZ40870.1 - 2.1e-44 151.4 0.0 2.8e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FtsH_ext PF06480.10 KEZ40870.1 - 0.038 14.1 0.0 0.14 12.3 0.0 1.8 1 1 1 2 2 2 0 FtsH Extracellular WD40 PF00400.27 KEZ40871.1 - 2e-30 103.5 7.9 2.2e-08 33.6 0.0 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat IKI3 PF04762.7 KEZ40871.1 - 0.021 12.6 0.0 0.1 10.3 0.0 1.8 1 1 1 2 2 2 0 IKI3 family Zn_Tnp_IS1595 PF12760.2 KEZ40871.1 - 0.063 13.0 1.6 0.14 12.0 1.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_S27 PF01599.14 KEZ40871.1 - 0.42 10.4 3.1 0.76 9.6 1.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S27a WD40 PF00400.27 KEZ40872.1 - 1.5e-25 88.1 10.9 5.7e-10 38.6 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KEZ40872.1 - 5.7e-19 67.7 0.0 1.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 KEZ40872.1 - 0.0022 16.8 0.6 0.2 10.3 0.2 2.3 1 1 1 2 2 2 2 Nup133 N terminal like Glyco_hydro_3 PF00933.16 KEZ40873.1 - 9e-15 54.4 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain HNH_2 PF13391.1 KEZ40877.1 - 1.4e-05 24.8 0.0 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease DUF3619 PF12279.3 KEZ40877.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) CorA PF01544.13 KEZ40878.1 - 2.4e-15 56.3 0.1 4.6e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1270 PF06900.6 KEZ40878.1 - 4.7 7.4 6.9 1.5 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Fungal_trans PF04082.13 KEZ40879.1 - 4.7e-19 68.2 0.3 8.8e-19 67.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain YqbF PF14553.1 KEZ40879.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 YqbF, hypothetical protein domain BLOC1_2 PF10046.4 KEZ40880.1 - 0.32 11.1 1.9 2.2 8.4 0.2 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3113 PF11310.3 KEZ40881.1 - 0.084 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) SpvB PF03534.8 KEZ40882.1 - 7.6e-77 258.1 0.0 1.5e-76 257.2 0.0 1.5 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.3 KEZ40882.1 - 9.2e-40 135.9 5.8 3e-33 114.7 0.0 5.9 5 1 1 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.3 KEZ40882.1 - 1e-26 93.3 0.1 2e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region RHS_repeat PF05593.9 KEZ40882.1 - 0.00069 19.7 45.6 0.031 14.4 1.1 11.3 12 0 0 12 12 12 3 RHS Repeat VCBS PF13517.1 KEZ40882.1 - 0.00082 19.6 17.9 0.0061 16.9 0.1 5.6 3 1 4 7 7 7 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEZ40882.1 - 0.82 9.4 12.5 0.7 9.6 0.0 4.5 4 0 0 4 4 4 0 FG-GAP repeat GMC_oxred_N PF00732.14 KEZ40883.1 - 1.9e-55 188.1 0.0 2.6e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ40883.1 - 2e-35 122.1 0.0 8.6e-35 120.1 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ40883.1 - 5.3e-06 25.5 0.0 0.0083 15.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ40883.1 - 1.9e-05 23.7 4.2 8.8e-05 21.5 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ40883.1 - 4.1e-05 23.5 3.0 0.00023 21.1 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ40883.1 - 0.005 16.9 0.0 0.085 12.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ40883.1 - 0.0054 16.6 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KEZ40883.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 KEZ40883.1 - 0.011 14.7 0.1 0.029 13.3 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEZ40883.1 - 0.036 13.8 0.1 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KEZ40883.1 - 0.036 12.5 0.8 0.055 11.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein CotJB PF12652.2 KEZ40884.1 - 0.19 11.8 0.3 0.19 11.8 0.2 2.2 2 1 0 2 2 2 0 CotJB protein CBF_beta PF02312.12 KEZ40884.1 - 2 8.0 8.9 6.2 6.3 0.9 2.1 2 0 0 2 2 2 0 Core binding factor beta subunit MFS_1 PF07690.11 KEZ40885.1 - 3.6e-25 88.4 32.8 4.5e-14 51.9 6.4 2.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Esterase_phd PF10503.4 KEZ40886.1 - 6.9e-13 48.3 3.6 7.3e-07 28.6 0.5 2.6 2 1 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEZ40886.1 - 9.3e-08 31.5 0.1 1.7e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ40886.1 - 0.02 14.6 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ40886.1 - 0.032 13.7 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KEZ40886.1 - 0.037 13.4 0.2 0.096 12.0 0.1 1.6 2 0 0 2 2 2 0 Putative esterase PalH PF08733.5 KEZ40887.1 - 0.14 10.9 5.8 0.16 10.7 4.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Cytochrom_B_C PF00032.12 KEZ40887.1 - 0.58 10.4 6.3 2.6 8.3 1.8 2.2 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF2708 PF10917.3 KEZ40887.1 - 8.6 6.2 7.7 1.3 8.8 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2708) DUF3176 PF11374.3 KEZ40888.1 - 6.6e-23 80.7 0.1 1.4e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MFS_1 PF07690.11 KEZ40889.1 - 2.1e-07 30.0 19.4 5.7e-07 28.5 13.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1127 PF06568.6 KEZ40889.1 - 0.018 14.4 0.3 0.096 12.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Polyketide_cyc2 PF10604.4 KEZ40890.1 - 5.7e-06 26.5 1.2 6.9e-06 26.2 0.8 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Rep_fac-A_3 PF08661.6 KEZ40890.1 - 0.054 13.4 0.1 0.11 12.4 0.0 1.6 1 1 1 2 2 2 0 Replication factor A protein 3 PAS_7 PF12860.2 KEZ40890.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 PAS fold Arylsulfotran_2 PF14269.1 KEZ40892.1 - 4.5e-72 242.7 0.9 5.8e-72 242.3 0.6 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KEZ40892.1 - 1.3e-16 60.2 0.2 7.6e-16 57.6 0.1 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 KEZ40893.1 - 1.4e-42 145.6 43.7 1.4e-42 145.6 30.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ40893.1 - 6.9e-13 47.9 28.8 2.3e-12 46.2 12.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter FA_hydroxylase PF04116.8 KEZ40894.1 - 4.1e-16 59.4 25.8 5.7e-16 58.9 16.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 KEZ40895.1 - 4.1e-33 114.5 34.0 4.1e-33 114.5 23.6 1.8 1 1 2 3 3 3 3 Major Facilitator Superfamily CopD PF05425.8 KEZ40895.1 - 4.7 7.4 16.9 15 5.8 0.1 4.2 2 1 2 4 4 4 0 Copper resistance protein D Glyco_hydro_75 PF07335.6 KEZ40896.1 - 5.4e-43 146.5 0.4 1.7e-42 144.9 0.2 1.7 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 MFS_1 PF07690.11 KEZ40897.1 - 0.00036 19.3 17.5 0.027 13.1 2.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1446 PF07287.6 KEZ40898.1 - 3.6e-107 357.9 0.2 4.7e-107 357.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) IL13 PF03487.8 KEZ40898.1 - 0.25 11.1 1.9 5 6.9 0.0 2.5 2 0 0 2 2 2 0 Interleukin-13 Carboxyl_trans PF01039.17 KEZ40899.1 - 1.3e-118 396.5 0.0 1.6e-118 396.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KEZ40900.1 - 1e-66 224.2 0.0 2e-66 223.3 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KEZ40900.1 - 8.4e-40 135.2 0.1 2e-39 134.1 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEZ40900.1 - 4.5e-32 110.2 0.0 1.2e-31 108.8 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 KEZ40900.1 - 6e-14 51.5 0.0 3.6e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KEZ40900.1 - 1.7e-11 43.5 0.7 5.4e-11 41.9 0.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KEZ40900.1 - 1.6e-10 40.9 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KEZ40900.1 - 2.2e-10 40.6 0.0 4.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEZ40900.1 - 3.4e-09 36.3 0.0 1.2e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEZ40900.1 - 3.2e-08 33.1 0.1 4e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KEZ40900.1 - 6.5e-05 22.5 0.0 0.00015 21.3 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like RimK PF08443.6 KEZ40900.1 - 0.00015 21.3 0.0 0.00037 20.0 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ECH PF00378.15 KEZ40901.1 - 4.9e-32 111.0 0.0 5.5e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 KEZ40902.1 - 4.8e-22 77.9 0.1 6.5e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ40902.1 - 3e-12 47.2 0.1 5.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.19 KEZ40903.1 - 3.2e-28 98.7 0.4 4.3e-28 98.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ40903.1 - 1.2e-20 72.7 1.2 1.9e-20 72.0 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEZ40903.1 - 1.6e-16 60.9 0.0 4.9e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEZ40903.1 - 0.0077 16.4 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SET PF00856.23 KEZ40904.1 - 4.1e-07 30.4 0.0 8.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Asparaginase_2 PF01112.13 KEZ40905.1 - 1.3e-42 145.6 0.2 2.6e-20 72.3 0.0 3.5 3 1 0 3 3 3 3 Asparaginase FAD_binding_4 PF01565.18 KEZ40907.1 - 2.8e-20 72.2 0.4 6.5e-20 71.0 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ40907.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_114 PF03537.8 KEZ40908.1 - 2.4e-23 81.7 0.1 3.3e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ETRAMP PF09716.5 KEZ40908.1 - 0.059 13.3 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_23 PF13489.1 KEZ40910.1 - 2.1e-09 37.2 0.0 3.4e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ40910.1 - 3.8e-07 30.5 0.0 1.2e-06 28.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ40910.1 - 0.00036 20.9 0.0 0.0011 19.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ40910.1 - 0.00054 19.5 0.0 0.0057 16.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ40910.1 - 0.0021 18.6 0.0 0.073 13.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ40910.1 - 0.025 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Fungal_trans PF04082.13 KEZ40911.1 - 4.6e-17 61.7 0.1 6.6e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40911.1 - 8.9e-07 28.7 11.1 2e-06 27.6 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Btz PF09405.5 KEZ40911.1 - 0.048 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Sugar_tr PF00083.19 KEZ40912.1 - 3.4e-60 203.8 11.6 4.9e-38 130.8 0.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ40912.1 - 0.008 14.9 20.6 1.1 7.9 14.5 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Herpes_gE PF02480.11 KEZ40913.1 - 0.005 15.1 0.1 0.0073 14.6 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E CD34_antigen PF06365.7 KEZ40913.1 - 0.012 15.2 0.1 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Adeno_E3_CR2 PF02439.10 KEZ40913.1 - 0.014 14.8 0.4 0.034 13.6 0.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RskA PF10099.4 KEZ40913.1 - 0.029 14.1 0.4 0.049 13.3 0.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TMEM51 PF15345.1 KEZ40913.1 - 0.044 13.4 0.1 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Protocadherin PF08374.6 KEZ40913.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protocadherin DUF1049 PF06305.6 KEZ40913.1 - 0.095 12.1 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) End_tail_spike PF12219.3 KEZ40914.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase zf-CHCC PF10276.4 KEZ40915.1 - 0.0045 16.8 4.6 0.89 9.4 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger domain zf-C2H2 PF00096.21 KEZ40915.1 - 0.0047 17.1 25.8 0.0079 16.4 0.6 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KEZ40915.1 - 0.02 15.0 2.3 0.02 15.0 1.6 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KEZ40915.1 - 0.39 11.1 22.7 0.1 12.9 0.7 4.7 3 1 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 KEZ40915.1 - 1.3 8.8 10.2 0.89 9.3 1.3 3.4 3 0 0 3 3 3 0 BED zinc finger zf-H2C2_2 PF13465.1 KEZ40915.1 - 7.5 7.0 13.2 0.19 12.1 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DSPc PF00782.15 KEZ40916.1 - 5.9e-12 45.3 0.0 6.9e-06 25.6 0.0 3.1 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Vfa1 PF08432.5 KEZ40917.1 - 5.6e-40 137.3 26.0 6.9e-40 137.0 18.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SPX PF03105.14 KEZ40917.1 - 0.016 15.0 16.0 0.017 14.9 11.1 1.1 1 0 0 1 1 1 0 SPX domain Utp14 PF04615.8 KEZ40917.1 - 0.017 13.3 28.4 0.02 13.0 19.7 1.0 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 KEZ40917.1 - 0.02 12.9 24.7 0.024 12.6 17.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 KEZ40917.1 - 0.02 12.6 16.1 0.023 12.4 11.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 KEZ40917.1 - 0.03 13.7 25.9 0.037 13.3 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rtf2 PF04641.7 KEZ40917.1 - 0.03 13.5 18.9 0.039 13.1 13.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger U79_P34 PF03064.11 KEZ40917.1 - 0.09 12.2 24.2 0.14 11.6 16.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 UPF0560 PF10577.4 KEZ40917.1 - 0.29 9.3 11.5 0.34 9.1 8.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 NARP1 PF12569.3 KEZ40917.1 - 0.41 9.3 21.2 0.45 9.2 14.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MIP-T3 PF10243.4 KEZ40917.1 - 0.41 9.0 40.0 0.53 8.6 27.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SelP_N PF04592.9 KEZ40917.1 - 0.46 9.8 7.4 0.59 9.4 5.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CobT PF06213.7 KEZ40917.1 - 0.63 9.1 21.8 0.92 8.5 15.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Raftlin PF15250.1 KEZ40917.1 - 0.91 7.9 12.4 1.1 7.7 8.6 1.1 1 0 0 1 1 1 0 Raftlin TP53IP5 PF15331.1 KEZ40917.1 - 1.2 9.0 17.7 1.5 8.7 12.3 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Paramyxo_ncap PF00973.14 KEZ40917.1 - 2.7 6.5 10.3 3.2 6.3 7.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF262 PF03235.9 KEZ40917.1 - 2.9 7.7 10.3 3.5 7.5 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 RP-C_C PF11800.3 KEZ40917.1 - 3 7.5 12.2 3.6 7.2 8.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Merozoite_SPAM PF07133.6 KEZ40917.1 - 3 7.6 32.9 4.6 7.1 22.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Pilt PF15453.1 KEZ40917.1 - 3.1 7.3 15.4 3.9 7.0 10.7 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions 60KD_IMP PF02096.15 KEZ40917.1 - 3.4 7.2 5.1 6.9 6.2 3.5 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Zip PF02535.17 KEZ40917.1 - 3.8 6.4 8.0 4.7 6.1 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2413 PF10310.4 KEZ40917.1 - 4.5 5.9 22.6 5.2 5.7 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Daxx PF03344.10 KEZ40917.1 - 6.4 5.1 24.7 7.3 4.9 17.2 1.0 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 KEZ40917.1 - 6.7 6.1 26.7 12 5.3 18.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Menin PF05053.8 KEZ40917.1 - 7.6 4.5 12.2 8.6 4.3 8.5 1.0 1 0 0 1 1 1 0 Menin RR_TM4-6 PF06459.7 KEZ40917.1 - 8 6.2 21.2 11 5.7 14.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 KEZ40917.1 - 8 5.3 15.0 10 4.9 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.2 KEZ40917.1 - 9.5 3.7 15.1 11 3.5 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rtt106 PF08512.7 KEZ40918.1 - 2.2e-24 85.2 0.0 1.3e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Nop14 PF04147.7 KEZ40918.1 - 7.7 4.3 34.6 10 3.8 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ldh_1_N PF00056.18 KEZ40919.1 - 3.7e-34 117.5 0.2 5.8e-34 116.9 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEZ40919.1 - 1.2e-24 87.0 0.0 3.1e-24 85.6 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Malic_M PF03949.10 KEZ40919.1 - 0.00018 21.1 0.0 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEZ40919.1 - 0.052 12.9 0.3 0.23 10.8 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KEZ40919.1 - 0.053 13.3 0.5 0.16 11.8 0.2 1.8 2 0 0 2 2 2 0 ThiF family OCD_Mu_crystall PF02423.10 KEZ40919.1 - 0.096 11.4 0.4 0.14 10.9 0.3 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family PT PF04886.7 KEZ40920.1 - 0.008 15.4 38.4 0.008 15.4 26.6 6.0 2 1 1 3 3 3 1 PT repeat DRMBL PF07522.9 KEZ40922.1 - 1.4e-06 28.2 0.0 3.9e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KEZ40922.1 - 3.5e-06 26.7 0.0 2.3e-05 24.0 0.0 2.0 1 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEZ40922.1 - 0.0029 17.3 0.7 0.0062 16.1 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily FAD_binding_3 PF01494.14 KEZ40923.1 - 6.3e-82 275.4 0.0 8.4e-82 275.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ40923.1 - 0.0014 17.6 0.2 0.0078 15.1 0.3 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ40923.1 - 0.0055 16.6 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ40923.1 - 0.024 14.6 1.6 0.066 13.2 1.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ40923.1 - 0.046 12.5 0.1 0.079 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KEZ40923.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KEZ40923.1 - 0.093 13.1 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ40923.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 KEZ40924.1 - 1.7e-12 47.0 1.9 6e-12 45.2 1.3 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ40924.1 - 5.4e-10 38.9 0.1 8.6e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KEZ40924.1 - 2.5e-07 30.1 0.1 5.6e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 KEZ40924.1 - 0.0046 16.1 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KEZ40924.1 - 0.021 15.3 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NYN PF01936.13 KEZ40925.1 - 3.6e-08 33.8 0.0 4.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NYN domain H_lectin PF09458.5 KEZ40925.1 - 0.14 11.8 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 H-type lectin domain DUF1903 PF08991.5 KEZ40927.1 - 0.076 13.1 0.4 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) PH_10 PF15411.1 KEZ40928.1 - 1.9e-44 150.5 0.5 3.4e-44 149.7 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KEZ40928.1 - 1.9e-33 115.8 0.8 2.8e-33 115.3 0.1 1.6 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 KEZ40928.1 - 2.3e-26 91.6 0.0 4.6e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 KEZ40928.1 - 2.2e-07 30.4 0.0 4.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 KEZ40928.1 - 0.065 13.4 0.2 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 PH domain Mob1_phocein PF03637.12 KEZ40929.1 - 1.9e-36 125.3 0.4 7.2e-20 71.3 0.1 2.1 2 0 0 2 2 2 2 Mob1/phocein family WD40 PF00400.27 KEZ40930.1 - 1.3e-37 126.3 2.8 8.4e-06 25.4 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KEZ40930.1 - 6.5e-13 48.1 2.0 1.4e-12 47.1 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ40930.1 - 1.2e-07 31.2 1.5 2.9e-07 29.9 0.6 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KEZ40930.1 - 0.018 13.2 0.1 1.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 MgtE_N PF03448.12 KEZ40930.1 - 0.025 14.9 0.0 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 MgtE intracellular N domain Beta-lactamase PF00144.19 KEZ40931.1 - 1.5e-50 172.1 0.1 1.9e-50 171.7 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF2458 PF10454.4 KEZ40931.1 - 0.015 15.2 0.1 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Beta-lactamase2 PF13354.1 KEZ40931.1 - 0.12 11.7 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase enzyme family DUF3425 PF11905.3 KEZ40932.1 - 2.2e-30 105.3 0.4 4.5e-30 104.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ADH_N PF08240.7 KEZ40933.1 - 1.3e-23 82.8 5.5 2e-23 82.2 3.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ40933.1 - 2.3e-17 62.7 0.0 3.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ40933.1 - 3.9e-06 27.7 0.0 6.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KEZ40933.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KEZ40933.1 - 0.11 11.6 0.1 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease PF00324.16 KEZ40935.1 - 4.8e-132 440.6 35.3 6e-132 440.3 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ40935.1 - 9.3e-40 136.4 38.1 1.1e-39 136.2 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease CFEM PF05730.6 KEZ40936.1 - 8.1e-10 38.3 11.5 1.2e-09 37.8 8.0 1.3 1 0 0 1 1 1 1 CFEM domain Microtub_assoc PF07989.6 KEZ40937.1 - 0.00068 19.4 6.3 0.00084 19.1 3.3 2.0 1 1 1 2 2 2 1 Microtubule associated bZIP_1 PF00170.16 KEZ40937.1 - 0.75 9.7 11.8 2.4 8.1 1.9 3.5 2 1 1 3 3 3 0 bZIP transcription factor APG6 PF04111.7 KEZ40937.1 - 2.5 7.0 7.5 4.4 6.2 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PRKCSH PF07915.8 KEZ40938.1 - 1.3e-18 67.5 2.4 2.2e-17 63.6 1.7 2.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KEZ40938.1 - 0.00055 19.4 0.0 0.059 12.8 0.0 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein Peptidase_U57 PF05582.7 KEZ40938.1 - 0.06 12.3 0.5 0.099 11.5 0.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 KH_1 PF00013.24 KEZ40940.1 - 1.8e-40 136.4 20.9 3.5e-15 55.3 3.4 3.8 4 1 0 4 4 4 3 KH domain KH_3 PF13014.1 KEZ40940.1 - 8.1e-28 95.5 31.6 1e-10 41.0 0.2 5.1 6 0 0 6 6 6 3 KH domain KH_4 PF13083.1 KEZ40940.1 - 1.5e-09 37.3 7.6 0.02 14.4 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KEZ40940.1 - 2.4e-09 36.5 7.7 0.018 14.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KEZ40940.1 - 7e-05 22.5 6.2 0.056 13.2 0.9 3.8 3 1 0 3 3 3 2 NusA-like KH domain SLS PF14611.1 KEZ40940.1 - 0.24 10.7 0.0 5.7 6.3 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator DEAD PF00270.24 KEZ40941.1 - 5.5e-45 152.8 0.0 1e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KEZ40941.1 - 5.4e-22 77.1 0.2 5.4e-22 77.1 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KEZ40941.1 - 7.4e-22 77.0 0.0 1.5e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Daxx PF03344.10 KEZ40941.1 - 0.046 12.2 24.8 0.06 11.8 17.2 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 KEZ40941.1 - 0.076 12.2 24.4 0.12 11.6 16.9 1.2 1 0 0 1 1 1 0 SDA1 ResIII PF04851.10 KEZ40941.1 - 0.097 12.4 0.0 0.097 12.4 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CDC45 PF02724.9 KEZ40941.1 - 0.17 9.8 15.9 0.25 9.3 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 KEZ40941.1 - 0.65 8.9 17.8 0.97 8.3 12.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC27 PF09507.5 KEZ40941.1 - 0.88 8.7 28.3 1.3 8.1 19.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 6PF2K PF01591.13 KEZ40942.1 - 3.7e-80 268.1 0.0 5.2e-80 267.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KEZ40942.1 - 3.1e-31 108.6 0.0 6.5e-31 107.5 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KEZ40942.1 - 1.8e-09 37.5 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEZ40942.1 - 2.8e-05 23.4 0.0 4.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEZ40942.1 - 0.00067 20.4 0.1 0.018 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Asp PF00026.18 KEZ40943.1 - 8.2e-43 146.8 0.0 1.1e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KEZ40943.1 - 0.0001 22.7 0.0 0.33 11.4 0.0 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KEZ40943.1 - 0.0002 20.9 0.2 0.0015 18.0 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF3337 PF11816.3 KEZ40944.1 - 2.8e-84 283.3 0.0 6.2e-80 269.0 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 KEZ40944.1 - 4.7e-30 102.3 5.3 4.3e-09 35.9 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ATP_bind_3 PF01171.15 KEZ40945.1 - 7e-38 129.9 0.0 1.7e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 KEZ40945.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase DUF4098 PF13345.1 KEZ40946.1 - 0.0019 18.0 19.5 0.11 12.5 0.3 5.7 6 1 1 7 7 7 4 Domain of unknown function (DUF4098) Mito_carr PF00153.22 KEZ40947.1 - 8.9e-65 214.4 8.2 2.2e-24 84.9 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KEZ40947.1 - 6.7e-20 70.9 0.6 3.2e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEZ40947.1 - 2e-18 64.2 5.8 4.9e-06 25.4 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 KEZ40947.1 - 1.1e-16 59.3 5.8 1.3e-05 24.3 0.8 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KEZ40947.1 - 3.1e-13 48.3 3.3 0.0014 18.3 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 KEZ40947.1 - 3.5e-10 39.3 2.2 0.00024 20.6 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KEZ40947.1 - 4.6e-09 36.2 0.0 2.8e-05 24.0 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pol_alpha_B_N PF08418.5 KEZ40947.1 - 0.31 10.5 9.5 0.52 9.8 6.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1675 PF07897.6 KEZ40947.1 - 0.74 9.6 8.0 1.2 8.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2217 PF10265.4 KEZ40947.1 - 0.92 8.1 6.4 1.3 7.7 4.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) TraG-D_C PF12696.2 KEZ40947.1 - 5.7 6.8 6.5 12 5.7 4.5 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Cyclin_N PF00134.18 KEZ40948.1 - 1.8e-12 46.9 2.3 3.6e-11 42.7 0.4 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KEZ40948.1 - 0.011 15.5 0.4 0.011 15.5 0.3 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat AMIN PF11741.3 KEZ40948.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 AMIN domain DUF4452 PF14618.1 KEZ40949.1 - 2e-71 239.1 13.8 2.4e-71 238.8 9.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) AAA_12 PF13087.1 KEZ40950.1 - 0.00024 20.5 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain SNARE PF05739.14 KEZ40952.1 - 2.7e-14 52.6 2.4 6.2e-14 51.4 1.7 1.7 1 0 0 1 1 1 1 SNARE domain TBCA PF02970.11 KEZ40952.1 - 0.023 14.7 2.2 0.12 12.4 0.2 2.4 2 1 0 2 2 2 0 Tubulin binding cofactor A ING PF12998.2 KEZ40952.1 - 0.12 12.6 3.0 0.24 11.6 0.2 2.2 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Med9 PF07544.8 KEZ40952.1 - 0.43 10.3 3.0 0.93 9.2 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 WD40 PF00400.27 KEZ40953.1 - 1.1e-05 25.0 8.5 0.0042 16.9 0.1 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Vps39_1 PF10366.4 KEZ40954.1 - 2.2e-35 120.9 0.5 3.2e-34 117.1 0.0 3.3 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KEZ40954.1 - 8.8e-15 54.8 0.0 3.2e-14 53.0 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KEZ40954.1 - 1.7e-14 53.9 0.0 1.8e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 CNH domain Clathrin PF00637.15 KEZ40954.1 - 0.00035 20.2 1.8 0.0064 16.0 0.1 3.1 3 0 0 3 3 3 1 Region in Clathrin and VPS Apc3 PF12895.2 KEZ40954.1 - 0.00037 20.5 1.5 0.63 10.2 0.1 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 KEZ40954.1 - 0.00041 20.9 0.2 0.23 12.1 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ40954.1 - 0.029 14.2 3.1 32 4.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ40954.1 - 0.048 13.2 8.7 0.94 9.2 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2615 PF11027.3 KEZ40954.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) TPR_11 PF13414.1 KEZ40954.1 - 4.9 6.8 9.7 10 5.8 0.0 4.5 5 1 1 6 6 6 0 TPR repeat LIM_bind PF01803.11 KEZ40955.1 - 7.2e-67 224.9 0.0 7.2e-67 224.9 0.0 4.0 4 1 1 5 5 5 1 LIM-domain binding protein Aminotran_1_2 PF00155.16 KEZ40956.1 - 3.3e-90 302.6 0.0 3.8e-90 302.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II JmjC PF02373.17 KEZ40957.1 - 2.3e-11 43.9 0.1 7.6e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 KEZ40957.1 - 0.00054 20.0 10.0 0.00054 20.0 6.9 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 KEZ40957.1 - 0.0017 17.7 0.2 0.0049 16.3 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Ribosom_S12_S23 PF00164.20 KEZ40958.1 - 5.1e-40 135.6 0.3 5.8e-40 135.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF2338 PF10100.4 KEZ40958.1 - 0.082 11.2 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Inhibitor_I9 PF05922.11 KEZ40959.1 - 0.0014 19.1 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 Reo_sigmaC PF04582.7 KEZ40960.1 - 0.0013 17.9 28.6 0.0074 15.5 0.7 4.3 3 1 1 4 4 4 3 Reovirus sigma C capsid protein ADK PF00406.17 KEZ40961.1 - 9.9e-59 197.5 0.0 1.3e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KEZ40961.1 - 2e-13 49.7 0.0 4.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KEZ40961.1 - 1.6e-06 28.9 0.0 2.9e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ40961.1 - 0.00027 20.8 0.0 0.0007 19.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEZ40961.1 - 0.0038 16.3 0.0 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KEZ40961.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 KEZ40962.1 - 1.3e-24 85.9 15.2 5.2e-12 45.5 1.7 6.4 3 2 3 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ40962.1 - 3.4e-16 58.9 0.0 5.7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 KEZ40962.1 - 3e-15 55.5 17.6 0.0081 16.0 0.1 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ40962.1 - 1.3e-11 43.9 8.2 1.2e-06 28.0 1.7 5.5 3 1 2 5 5 5 3 TPR repeat TPR_7 PF13176.1 KEZ40962.1 - 2.1e-09 36.4 4.6 0.01 15.5 0.4 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ40962.1 - 1.6e-07 30.7 14.0 0.063 13.2 1.3 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ40962.1 - 7e-07 28.5 7.1 0.00011 21.5 0.8 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ40962.1 - 2.6e-06 27.6 11.6 0.033 14.5 1.5 6.1 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ40962.1 - 4.6e-06 26.0 3.2 3 7.8 0.7 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ40962.1 - 0.00013 22.3 14.0 40 5.2 0.4 8.3 5 2 3 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ40962.1 - 0.00024 21.0 0.0 6.7 7.1 0.0 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat KaiC PF06745.8 KEZ40962.1 - 0.0018 17.4 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 KaiC PPR PF01535.15 KEZ40962.1 - 0.0091 15.9 1.8 12 6.0 0.0 5.0 5 0 0 5 5 5 0 PPR repeat ArsA_ATPase PF02374.10 KEZ40962.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase IstB_IS21 PF01695.12 KEZ40962.1 - 0.03 13.7 0.0 0.077 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.1 KEZ40962.1 - 0.042 13.9 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Apc5 PF12862.2 KEZ40962.1 - 0.048 13.4 0.2 0.55 10.1 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_16 PF13432.1 KEZ40962.1 - 0.06 14.0 11.1 2.4 8.9 0.2 5.3 3 2 3 6 6 5 0 Tetratricopeptide repeat AAA_25 PF13481.1 KEZ40962.1 - 0.07 12.5 0.1 0.21 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KEZ40962.1 - 0.14 11.6 0.2 0.35 10.2 0.1 1.7 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain TPR_6 PF13174.1 KEZ40962.1 - 0.22 12.0 6.8 14 6.3 0.0 6.1 8 0 0 8 8 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 KEZ40962.1 - 3.2 8.2 6.3 30 5.2 0.1 4.9 6 0 0 6 6 3 0 Pentatricopeptide repeat domain MitMem_reg PF13012.1 KEZ40963.1 - 2.9e-38 130.4 0.1 8e-38 129.0 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KEZ40963.1 - 1.1e-27 95.9 0.2 2.8e-27 94.7 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1682 PF07946.9 KEZ40963.1 - 0.28 9.9 7.1 0.38 9.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NARP1 PF12569.3 KEZ40963.1 - 1.1 7.8 8.6 1.9 7.1 6.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Coprogen_oxidas PF01218.13 KEZ40964.1 - 7.2e-135 448.2 0.1 8.3e-135 448.0 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 KEZ40965.1 - 8.5e-51 170.2 0.2 1e-50 170.0 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KEZ40965.1 - 6.2e-06 26.3 0.0 7.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Lustrin_cystein PF14625.1 KEZ40966.1 - 2.4 8.2 6.6 2.6 8.1 1.7 2.2 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain zf-TRM13_CCCH PF11722.3 KEZ40967.1 - 0.13 11.6 0.3 0.13 11.6 0.2 7.5 10 0 0 10 10 10 0 CCCH zinc finger in TRM13 protein TPR_2 PF07719.12 KEZ40968.1 - 2.6e-09 36.2 2.3 0.15 12.0 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ40968.1 - 2.6e-08 33.6 7.0 0.0018 18.1 0.5 4.4 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ40968.1 - 3.8e-07 29.4 0.0 1.3 8.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ40968.1 - 4.3e-06 26.2 1.2 0.0052 16.4 0.1 3.2 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KEZ40968.1 - 2.1e-05 23.9 0.1 0.27 11.1 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ40968.1 - 4e-05 23.4 1.1 0.26 11.2 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ40968.1 - 0.00012 22.4 7.3 1.7 9.4 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ40968.1 - 0.00074 19.1 2.2 3.9 7.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ40968.1 - 0.0032 18.0 5.4 0.27 11.9 0.6 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ40968.1 - 0.016 15.5 1.6 0.12 12.7 0.1 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Ank PF00023.25 KEZ40969.1 - 2.6e-05 23.7 0.6 2.5 8.0 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEZ40969.1 - 0.00028 21.1 0.0 0.11 12.8 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ40969.1 - 0.0022 18.0 0.3 13 6.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 KEZ40969.1 - 0.12 12.9 0.0 3 8.4 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ40969.1 - 0.14 12.4 1.0 14 6.1 0.1 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF619 PF04768.8 KEZ40970.1 - 2.6e-42 144.1 0.0 4.8e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) BAR_2 PF10455.4 KEZ40971.1 - 4.5e-60 203.0 0.9 6.8e-60 202.4 0.7 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KEZ40971.1 - 1e-19 70.9 1.6 9.1e-19 67.8 1.1 1.9 1 1 0 1 1 1 1 BAR domain GAS PF13851.1 KEZ40971.1 - 0.19 10.8 2.0 6.9 5.8 0.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ETC_C1_NDUFA5 PF04716.9 KEZ40972.1 - 2.3e-19 68.6 0.5 2.3e-19 68.6 0.4 2.2 2 0 0 2 2 2 1 ETC complex I subunit conserved region WD40 PF00400.27 KEZ40973.1 - 1.6e-16 59.5 17.2 7.2e-08 32.0 0.3 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat Ran_BP1 PF00638.13 KEZ40974.1 - 1.8e-05 24.7 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain MIF4G PF02854.14 KEZ40975.1 - 2.5e-58 196.9 0.0 4.1e-29 101.4 0.0 3.4 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.9 KEZ40975.1 - 1.8e-49 167.7 12.2 1.8e-49 167.7 8.4 2.1 2 0 0 2 2 2 1 Up-frameshift suppressor 2 DEAD PF00270.24 KEZ40975.1 - 4.9e-15 55.4 0.0 9.8e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ40975.1 - 2.1e-08 33.8 0.0 1.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 KEZ40975.1 - 0.0036 17.2 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 1 DNA replication factor CDT1 like HSP70 PF00012.15 KEZ40976.1 - 9.1e-170 565.4 3.1 2.1e-169 564.2 2.1 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ40976.1 - 3.3e-14 52.2 0.0 1.6e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 KEZ40976.1 - 4.7e-05 23.2 0.3 0.72 9.7 0.0 4.1 3 1 0 3 3 3 2 Cell division protein FtsA Trans_reg_C PF00486.23 KEZ40976.1 - 0.0058 16.5 0.0 0.02 14.7 0.0 2.0 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Ketoacyl-synt_C PF02801.17 KEZ40976.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain GTP_EFTU PF00009.22 KEZ40977.1 - 1.7e-32 112.4 0.0 6.5e-32 110.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEZ40977.1 - 4.9e-18 64.9 0.0 1.6e-17 63.3 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KEZ40977.1 - 1.3e-11 44.3 3.3 6.1e-07 29.4 0.2 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEZ40977.1 - 8.4e-06 25.7 0.1 3.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEZ40977.1 - 0.0019 17.7 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MAP7 PF05672.6 KEZ40977.1 - 0.0021 17.4 30.2 0.0021 17.4 20.9 4.4 4 0 0 4 4 4 3 MAP7 (E-MAP-115) family Miro PF08477.8 KEZ40977.1 - 0.015 15.7 0.9 0.046 14.2 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 KEZ40977.1 - 0.028 14.5 0.1 0.2 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMS1_N PF10433.4 KEZ40978.1 - 6.9e-80 268.5 0.0 1.1e-79 267.9 0.0 1.3 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleoporin_N PF08801.6 KEZ40978.1 - 0.076 11.7 0.0 0.95 8.1 0.0 2.3 2 1 0 3 3 3 0 Nup133 N terminal like RabGAP-TBC PF00566.13 KEZ40979.1 - 4.7e-16 58.9 0.0 4.9e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Vps52 PF04129.7 KEZ40980.1 - 7.2e-125 417.4 0.0 8.7e-125 417.1 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 KEZ40980.1 - 0.0005 18.3 0.0 0.0009 17.5 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF1664 PF07889.7 KEZ40980.1 - 0.094 12.5 0.1 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) eIF-5a PF01287.15 KEZ40981.1 - 6.5e-26 90.0 1.1 9.3e-26 89.5 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KEZ40981.1 - 2.6e-05 23.7 0.8 5.7e-05 22.6 0.6 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KEZ40981.1 - 0.0078 16.0 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.19 KEZ40981.1 - 0.01 15.8 0.1 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain ubiquitin PF00240.18 KEZ40982.1 - 5.3e-34 115.4 0.9 8e-34 114.8 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KEZ40982.1 - 3e-30 103.5 10.7 5.2e-30 102.8 7.4 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 KEZ40982.1 - 4.7e-19 67.8 0.7 7.6e-19 67.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEZ40982.1 - 1.9e-05 24.7 0.2 6.5e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KEZ40982.1 - 0.00064 19.4 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KEZ40982.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEZ40982.1 - 0.039 14.1 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Peptidase_S80 PF07230.6 KEZ40982.1 - 0.079 11.2 0.0 0.099 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Tash_PEST PF07708.6 KEZ40982.1 - 0.49 10.4 2.7 2.8 7.9 1.2 2.3 2 0 0 2 2 2 0 Tash protein PEST motif Yip1 PF04893.12 KEZ40983.1 - 2.4e-11 43.4 16.7 4.3e-11 42.6 11.6 1.5 1 1 0 1 1 1 1 Yip1 domain Rhodanese PF00581.15 KEZ40984.1 - 1.7e-12 47.6 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.17 KEZ40985.1 - 3.1e-53 180.9 0.0 5.4e-53 180.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 TGT PF01702.13 KEZ40986.1 - 3.7e-88 294.8 0.0 4.6e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Mit_ribos_Mrp51 PF11709.3 KEZ40987.1 - 9.9e-60 202.3 0.0 1.7e-59 201.6 0.0 1.3 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 KEZ40988.1 - 4.6e-58 194.2 0.3 5.5e-58 194.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KEZ40988.1 - 0.0053 17.4 0.0 0.0073 16.9 0.0 1.2 1 0 0 1 1 1 1 Blue/Ultraviolet sensing protein C terminal SH3_2 PF07653.12 KEZ40989.1 - 4.1e-11 42.1 0.0 7.7e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ40989.1 - 7.2e-11 41.3 0.2 7.2e-11 41.3 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KEZ40989.1 - 4.3e-10 39.0 0.1 1e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Spc97_Spc98 PF04130.8 KEZ40990.1 - 2.5e-62 210.9 0.0 5.7e-62 209.7 0.0 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family Senescence PF06911.7 KEZ40991.1 - 1.3e-46 158.5 5.0 2e-46 157.9 3.5 1.3 1 0 0 1 1 1 1 Senescence-associated protein Fungal_trans PF04082.13 KEZ40992.1 - 1.3e-21 76.7 0.0 2.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ40992.1 - 4.4e-07 29.6 7.3 8.5e-07 28.7 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KEZ40992.1 - 3.7 6.8 11.5 6.7 5.9 8.0 1.3 1 0 0 1 1 1 0 Vta1 like FGE-sulfatase PF03781.11 KEZ40993.1 - 4.2e-18 65.6 0.2 1.1e-16 60.9 0.2 2.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_33 PF10017.4 KEZ40993.1 - 5.3e-17 61.8 0.0 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DinB_2 PF12867.2 KEZ40993.1 - 2.5e-06 27.8 2.7 2.8e-06 27.7 0.3 2.3 2 0 0 2 2 2 1 DinB superfamily GyrI-like PF06445.10 KEZ40993.1 - 0.00038 20.5 0.0 0.00089 19.3 0.0 1.6 1 0 0 1 1 1 1 GyrI-like small molecule binding domain IF-2B PF01008.12 KEZ40994.1 - 1.2e-38 132.7 0.0 1.4e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family ChW PF07538.6 KEZ40994.1 - 0.02 14.3 0.1 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Clostridial hydrophobic W Radical_SAM PF04055.16 KEZ40995.1 - 1.2e-09 38.5 0.0 2.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KEZ40995.1 - 4.9e-06 26.7 0.0 9.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KEZ40995.1 - 0.0022 18.0 0.1 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF221 PF02714.10 KEZ40996.1 - 7.9e-105 350.2 23.1 7.9e-105 350.2 16.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEZ40996.1 - 1.5e-42 144.8 0.4 1.5e-42 144.8 0.3 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KEZ40996.1 - 1.6e-27 95.2 0.3 5.7e-27 93.4 0.1 2.0 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KEZ40996.1 - 4.4e-20 71.9 0.2 8.5e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) WSC PF01822.14 KEZ40997.1 - 1.8e-10 40.6 10.1 2.9e-10 39.9 7.0 1.4 1 0 0 1 1 1 1 WSC domain DUF4328 PF14219.1 KEZ40997.1 - 0.0074 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) Podoplanin PF05808.6 KEZ40997.1 - 0.065 12.7 0.5 0.11 12.0 0.3 1.3 1 0 0 1 1 1 0 Podoplanin P12 PF12669.2 KEZ40997.1 - 0.2 11.8 0.2 0.2 11.8 0.1 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family SKG6 PF08693.5 KEZ40997.1 - 0.64 9.3 5.1 1.4 8.3 3.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2613 PF11021.3 KEZ40997.1 - 6.9 6.4 9.1 0.073 12.7 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Solute_trans_a PF03619.11 KEZ40998.1 - 1e-78 264.4 23.1 1.2e-78 264.1 16.0 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Colicin_V PF02674.11 KEZ40998.1 - 4.6 7.0 8.9 1.3 8.8 1.2 2.7 2 1 0 2 2 2 0 Colicin V production protein Tho2 PF11262.3 KEZ40999.1 - 5.6e-84 281.6 0.1 9.8e-84 280.9 0.1 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KEZ40999.1 - 2.6e-27 94.4 0.1 9.3e-27 92.6 0.1 2.0 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.15 KEZ41000.1 - 2.1e-41 142.0 0.0 1.8e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ41000.1 - 1.7e-12 47.7 0.1 1.4e-05 25.1 0.1 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KEZ41000.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein GRAM PF02893.15 KEZ41001.1 - 1e-16 60.1 0.0 2.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain CENP-Q PF13094.1 KEZ41002.1 - 0.0035 17.3 4.2 0.0035 17.3 2.9 3.8 2 2 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Taq-exonuc PF09281.5 KEZ41002.1 - 0.023 14.8 0.2 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Taq polymerase, exonuclease BLOC1_2 PF10046.4 KEZ41002.1 - 0.15 12.2 1.8 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 KEZ41002.1 - 0.2 11.4 10.6 2.1 8.1 3.0 2.6 1 1 0 2 2 2 0 Prefoldin subunit bZIP_1 PF00170.16 KEZ41002.1 - 0.22 11.4 10.4 3.5 7.6 0.3 3.2 2 1 0 2 2 2 0 bZIP transcription factor Hemerythrin PF01814.18 KEZ41002.1 - 0.26 11.4 4.2 11 6.1 0.1 3.2 3 0 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF972 PF06156.8 KEZ41002.1 - 0.61 10.4 8.7 2.1 8.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Spc24 PF08286.6 KEZ41002.1 - 0.71 9.5 6.1 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Cep57_CLD_2 PF14197.1 KEZ41002.1 - 0.96 9.4 8.7 4.4 7.3 2.5 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4164 PF13747.1 KEZ41002.1 - 1.3 9.1 10.4 1.3 9.2 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TMF_DNA_bd PF12329.3 KEZ41002.1 - 2.7 7.8 19.6 0.75 9.6 3.5 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.16 KEZ41002.1 - 2.8 8.2 8.1 1.4 9.2 2.8 2.4 2 0 0 2 2 2 0 Spectrin repeat Snapin_Pallidin PF14712.1 KEZ41002.1 - 5.3 7.4 8.3 4.5 7.6 0.4 2.6 2 0 0 2 2 2 0 Snapin/Pallidin IncA PF04156.9 KEZ41002.1 - 7.6 6.0 15.7 5.5 6.5 2.1 3.2 3 0 0 3 3 3 0 IncA protein Fungal_trans_2 PF11951.3 KEZ41003.1 - 0.00011 20.8 0.2 0.00042 19.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41003.1 - 0.00056 19.7 1.0 0.0011 18.7 0.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2418 PF10332.4 KEZ41004.1 - 9.8e-35 118.8 0.3 1.8e-34 117.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 KEZ41005.1 - 5.2e-25 87.6 0.3 6.1e-25 87.4 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF4097 PF13349.1 KEZ41005.1 - 0.068 12.7 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) E1_DerP2_DerF2 PF02221.10 KEZ41006.1 - 1.7e-26 93.0 0.4 2e-26 92.8 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KEZ41006.1 - 0.0031 17.5 0.1 0.016 15.2 0.1 1.9 1 1 0 1 1 1 1 ML-like domain Adenylsucc_synt PF00709.16 KEZ41007.1 - 3.5e-155 516.7 0.0 4e-155 516.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1719 PF08224.6 KEZ41007.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Glycos_transf_4 PF00953.16 KEZ41008.1 - 2.3e-28 99.0 9.9 2.3e-28 99.0 6.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 F-box-like PF12937.2 KEZ41009.1 - 7.8e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Serglycin PF04360.7 KEZ41009.1 - 0.00039 20.1 1.9 0.0013 18.4 1.3 1.9 1 0 0 1 1 1 1 Serglycin F-box-like_2 PF13013.1 KEZ41009.1 - 0.0012 18.5 0.1 0.0048 16.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like domain DUF1068 PF06364.7 KEZ41009.1 - 0.0043 16.6 0.2 0.01 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1068) F-box PF00646.28 KEZ41009.1 - 0.0053 16.3 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain AA_permease PF00324.16 KEZ41011.1 - 1.4e-09 36.8 0.3 2e-09 36.3 0.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1819 PF08849.6 KEZ41011.1 - 0.15 11.4 0.3 0.27 10.6 0.2 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Aconitase PF00330.15 KEZ41012.1 - 9.1e-180 598.0 0.0 9.1e-180 598.0 0.0 1.4 2 0 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEZ41012.1 - 1.1e-45 154.9 0.0 2.1e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_16 PF10294.4 KEZ41013.1 - 3.7e-15 55.7 0.0 1.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.7 KEZ41013.1 - 0.0062 16.9 0.0 0.092 13.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41013.1 - 0.02 14.4 0.0 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KEZ41013.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KEZ41013.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain EF-hand_1 PF00036.27 KEZ41014.1 - 2.2e-25 85.9 11.9 3.8e-08 32.0 0.2 4.6 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KEZ41014.1 - 1.5e-23 80.4 4.9 3.4e-06 26.4 0.1 5.0 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 KEZ41014.1 - 6.5e-21 74.2 5.9 5.4e-13 48.8 0.6 3.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEZ41014.1 - 1.2e-17 62.3 13.4 2.5e-05 23.3 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KEZ41014.1 - 7.1e-15 54.3 11.3 5.3e-06 25.9 0.7 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KEZ41014.1 - 6.1e-09 35.5 5.6 0.0038 16.9 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KEZ41014.1 - 0.00012 21.9 0.6 0.013 15.3 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KEZ41014.1 - 0.00071 19.5 1.4 0.56 10.2 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 KEZ41014.1 - 0.0082 16.2 0.2 1.4 8.9 0.0 3.2 3 1 1 4 4 4 1 EF hand EF-hand_10 PF14788.1 KEZ41014.1 - 0.013 15.1 2.8 1.9 8.1 0.0 3.8 4 0 0 4 4 4 0 EF hand DUF1679 PF07914.6 KEZ41014.1 - 0.02 13.5 0.3 1.5 7.4 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) RMMBL PF07521.7 KEZ41014.1 - 0.1 12.4 0.1 0.98 9.2 0.0 2.5 3 0 0 3 3 3 0 RNA-metabolising metallo-beta-lactamase Fungal_trans PF04082.13 KEZ41015.1 - 4.4e-06 25.7 0.7 5.5e-06 25.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC45 PF02724.9 KEZ41016.1 - 2.7e-233 775.5 0.0 4e-233 774.9 0.0 1.5 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.7 KEZ41016.1 - 0.0085 15.8 7.8 0.0085 15.8 5.4 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.4 KEZ41016.1 - 0.24 11.4 26.4 0.027 14.5 8.8 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Daxx PF03344.10 KEZ41016.1 - 0.38 9.1 36.2 0.059 11.8 7.0 2.1 2 0 0 2 2 2 0 Daxx Family Spore_coat_CotO PF14153.1 KEZ41016.1 - 1.2 8.5 18.4 0.24 10.8 4.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO FAM60A PF15396.1 KEZ41016.1 - 2.8 7.6 7.9 0.24 11.1 0.2 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Methyltransf_23 PF13489.1 KEZ41018.1 - 5.4e-15 55.4 0.0 8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41018.1 - 8e-09 36.0 0.0 4.1e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41018.1 - 3.5e-08 33.1 0.0 2.3e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41018.1 - 5.5e-07 29.9 0.0 3.2e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41018.1 - 2.2e-06 28.0 0.0 4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ41018.1 - 0.00023 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KEZ41018.1 - 0.0011 19.0 0.0 0.0035 17.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ41018.1 - 0.0031 16.5 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ41018.1 - 0.0034 17.7 0.0 0.0088 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ41018.1 - 0.0039 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KEZ41018.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KEZ41018.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KEZ41018.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fungal_trans PF04082.13 KEZ41019.1 - 1.3e-17 63.6 0.0 2.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41019.1 - 1.7e-08 34.2 11.6 3.2e-08 33.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEZ41020.1 - 2.3e-22 79.2 43.8 7.7e-13 47.8 5.0 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ41020.1 - 9.5e-07 27.7 25.1 6.4e-05 21.7 4.3 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter NB-ARC PF00931.17 KEZ41021.1 - 5.6e-13 48.3 0.0 1.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 KEZ41021.1 - 3.5e-09 36.4 8.2 0.00026 20.8 0.2 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ41021.1 - 1.2e-07 31.2 1.5 0.001 18.6 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.1 KEZ41021.1 - 1.4e-07 31.9 13.9 3.5e-05 24.3 0.4 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ41021.1 - 2.6e-07 30.0 12.8 0.056 13.3 0.1 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat DUF676 PF05057.9 KEZ41021.1 - 4.7e-07 29.3 0.0 7.9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_19 PF14559.1 KEZ41021.1 - 8.4e-06 26.0 6.0 0.44 10.9 0.1 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ41021.1 - 3.3e-05 24.1 15.3 0.29 11.8 0.2 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ41021.1 - 7.6e-05 22.7 11.6 0.33 11.4 0.5 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ41021.1 - 0.00017 21.1 8.8 0.025 14.3 0.1 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ41021.1 - 0.00036 20.8 7.1 0.32 11.5 0.4 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.7 KEZ41021.1 - 0.00066 19.3 0.0 0.0018 17.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.1 KEZ41021.1 - 0.0012 18.4 2.3 4.1 7.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ41021.1 - 0.0017 17.8 5.0 1.5 8.5 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ41021.1 - 0.0035 17.2 7.0 0.99 9.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PGAP1 PF07819.8 KEZ41021.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PhoH PF02562.11 KEZ41021.1 - 0.013 14.7 0.1 0.035 13.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 KEZ41021.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEZ41021.1 - 0.015 15.4 0.0 0.047 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KEZ41021.1 - 0.055 13.9 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein LCAT PF02450.10 KEZ41021.1 - 0.24 10.3 0.0 0.42 9.5 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase TPR_21 PF09976.4 KEZ41021.1 - 0.37 10.7 1.5 1.2 9.1 0.2 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat CM_2 PF01817.16 KEZ41022.1 - 5e-09 36.1 1.0 2.7e-06 27.3 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 KEZ41023.1 - 2.6e-38 128.5 8.5 2e-10 40.1 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KEZ41023.1 - 0.0003 19.0 12.5 0.16 10.0 0.1 5.1 4 2 2 6 6 6 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KEZ41023.1 - 0.013 15.3 0.0 0.33 10.7 0.0 3.1 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF3984 PF13136.1 KEZ41023.1 - 0.028 13.6 0.5 0.028 13.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) APG6 PF04111.7 KEZ41023.1 - 0.046 12.7 0.3 0.074 12.0 0.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BCIP PF13862.1 KEZ41024.1 - 7.5e-58 195.2 0.0 9.2e-58 194.9 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein FKBP_C PF00254.23 KEZ41025.1 - 1.6e-27 95.3 0.0 1.9e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 KEZ41026.1 - 1.6e-48 164.0 0.1 1e-28 99.8 0.0 2.9 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 KEZ41026.1 - 1.1e-37 129.0 0.0 2.1e-37 128.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 KEZ41026.1 - 2.2e-35 120.0 5.4 2.9e-27 94.0 0.1 2.8 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEZ41026.1 - 1.3e-22 78.8 1.5 2.5e-16 58.7 0.4 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site WD40 PF00400.27 KEZ41027.1 - 1.7e-17 62.5 0.6 0.00011 21.9 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Herpes_UL42 PF02282.11 KEZ41027.1 - 0.014 15.0 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) Zip PF02535.17 KEZ41027.1 - 1.5 7.7 3.7 2.1 7.3 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vps5 PF09325.5 KEZ41028.1 - 3.9e-15 55.7 2.8 6.1e-15 55.1 2.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KEZ41028.1 - 3e-08 33.4 0.0 6.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 PX domain ADH_N PF08240.7 KEZ41029.1 - 2.2e-26 91.7 0.6 5.1e-26 90.5 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ41029.1 - 8.3e-15 54.4 0.8 1.1e-13 50.7 0.6 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DAO PF01266.19 KEZ41029.1 - 0.0098 14.8 0.4 0.019 13.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 KEZ41029.1 - 0.018 14.4 0.3 0.073 12.4 0.3 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 KEZ41029.1 - 0.028 14.5 0.1 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KEZ41029.1 - 0.038 13.6 0.3 0.065 12.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 KEZ41029.1 - 0.056 13.3 0.2 1.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 KEZ41029.1 - 0.066 13.0 1.1 0.15 11.9 0.2 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_3 PF13738.1 KEZ41029.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KEZ41029.1 - 0.1 12.3 1.1 0.2 11.4 0.7 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.1 KEZ41029.1 - 0.13 12.2 1.1 0.5 10.4 0.3 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ41029.1 - 0.14 12.6 0.9 0.36 11.2 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ41029.1 - 0.19 10.1 0.5 0.3 9.5 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein JAB PF01398.16 KEZ41030.1 - 1.3e-09 37.8 0.0 8.4e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEZ41030.1 - 4.4e-05 23.5 2.5 0.00057 19.9 0.3 2.9 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function XAP5 PF04921.9 KEZ41030.1 - 3.1 7.2 7.4 6.4 6.2 5.1 1.5 1 1 0 1 1 1 0 XAP5, circadian clock regulator Aldo_ket_red PF00248.16 KEZ41031.1 - 4.8e-77 258.5 0.0 5.4e-77 258.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.19 KEZ41031.1 - 0.017 14.4 0.2 0.034 13.4 0.1 1.8 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel HNH_2 PF13391.1 KEZ41032.1 - 3.3e-13 49.2 0.0 1.2e-11 44.2 0.0 2.5 2 0 0 2 2 2 1 HNH endonuclease tRNA-synt_1d PF00750.14 KEZ41033.1 - 1.2e-70 238.0 0.5 2.5e-70 237.0 0.4 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KEZ41033.1 - 1.1e-24 86.6 1.5 3.9e-24 84.8 0.2 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain DUF3632 PF12311.3 KEZ41034.1 - 2.6e-24 86.0 2.4 3.6e-24 85.5 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) MAS20 PF02064.10 KEZ41036.1 - 6.9e-18 64.7 0.7 7.2e-17 61.4 0.5 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor DUF533 PF04391.7 KEZ41036.1 - 0.034 13.5 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Metallophos PF00149.23 KEZ41037.1 - 4.8e-43 146.9 0.8 7.4e-43 146.2 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 KEZ41037.1 - 3e-13 49.4 0.8 3e-13 49.4 0.5 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Laminin_B PF00052.13 KEZ41037.1 - 0.043 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Laminin B (Domain IV) cwf21 PF08312.7 KEZ41037.1 - 1.4 8.8 7.1 4.9 7.0 0.0 3.4 3 0 0 3 3 3 0 cwf21 domain Chitin_synth_2 PF03142.10 KEZ41038.1 - 9.4e-256 849.2 3.2 1.3e-255 848.8 2.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KEZ41038.1 - 4.8e-170 566.9 0.0 6.2e-170 566.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 KEZ41038.1 - 2e-20 72.2 0.3 3.7e-19 68.2 0.3 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 KEZ41038.1 - 5.9e-16 58.7 5.3 5.9e-16 58.7 3.7 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 KEZ41038.1 - 7.9e-16 57.6 0.0 1.8e-10 40.4 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KEZ41038.1 - 1.7e-15 57.4 0.3 5.1e-12 46.0 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEZ41038.1 - 0.00024 20.8 0.0 0.045 13.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 KEZ41038.1 - 0.00079 19.4 0.2 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KEZ41038.1 - 0.0027 17.6 0.1 0.53 10.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ41038.1 - 0.003 16.7 0.1 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ41038.1 - 0.0043 17.1 0.4 0.041 14.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ41038.1 - 0.0051 16.2 0.1 0.021 14.3 0.1 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KEZ41038.1 - 0.0072 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain Glyco_transf_21 PF13506.1 KEZ41038.1 - 0.014 14.7 0.2 0.055 12.7 0.2 2.0 2 1 0 2 2 2 0 Glycosyl transferase family 21 ABC_tran PF00005.22 KEZ41038.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KEZ41038.1 - 0.067 12.8 0.3 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEZ41038.1 - 0.099 12.8 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Chitin_synth_2 PF03142.10 KEZ41039.1 - 3e-229 761.8 0.0 3.9e-229 761.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KEZ41039.1 - 1.1e-57 195.5 0.0 1.1e-56 192.3 0.0 2.3 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KEZ41039.1 - 1.4e-20 72.8 0.0 4.7e-14 51.9 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 KEZ41039.1 - 8.4e-17 61.5 2.5 8.4e-17 61.5 1.7 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KEZ41039.1 - 1.5e-14 53.4 3.0 1.1e-13 50.7 1.8 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KEZ41039.1 - 3.4e-14 53.2 0.0 2.3e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEZ41039.1 - 4.6e-06 26.0 0.0 1.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEZ41039.1 - 0.00036 20.2 0.3 0.034 13.8 0.0 3.0 3 0 0 3 3 3 1 Glycosyl transferase family 2 Jiv90 PF14901.1 KEZ41039.1 - 0.12 12.3 0.2 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone BCDHK_Adom3 PF10436.4 KEZ41040.1 - 1.3e-41 141.8 0.0 1.8e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEZ41040.1 - 7.1e-17 61.1 0.0 2.4e-15 56.1 0.0 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEZ41040.1 - 0.054 13.1 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 KEZ41041.1 - 2.8e-13 50.2 0.0 3.2e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF663 PF04950.7 KEZ41042.1 - 1.2e-92 310.1 0.2 1.2e-92 310.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KEZ41042.1 - 1.7e-27 94.7 0.0 1.1e-25 88.9 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 KEZ41042.1 - 1e-05 25.6 0.0 3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 KEZ41042.1 - 1.8e-05 24.2 0.0 0.0064 15.9 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KEZ41042.1 - 5.9e-05 23.2 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KEZ41042.1 - 0.0001 21.9 0.0 0.00025 20.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 KEZ41042.1 - 0.00026 21.2 0.0 0.00098 19.4 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KEZ41042.1 - 0.0003 20.4 0.1 0.00081 19.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEZ41042.1 - 0.00046 20.9 0.0 0.00046 20.9 0.0 4.9 3 1 0 4 4 2 1 AAA domain MMR_HSR1 PF01926.18 KEZ41042.1 - 0.00048 20.0 0.0 0.0017 18.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 KEZ41042.1 - 0.00073 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEZ41042.1 - 0.00074 19.8 5.8 0.0056 16.9 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEZ41042.1 - 0.00091 19.1 0.8 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KEZ41042.1 - 0.0012 19.3 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 KEZ41042.1 - 0.0013 18.4 0.2 0.0043 16.7 0.1 2.1 2 1 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KEZ41042.1 - 0.0013 18.1 0.0 0.0041 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEZ41042.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KEZ41042.1 - 0.004 16.6 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 KEZ41042.1 - 0.0051 16.2 0.0 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KEZ41042.1 - 0.0056 15.8 0.0 0.034 13.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEZ41042.1 - 0.0078 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 KEZ41042.1 - 0.0086 15.7 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.1 KEZ41042.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KEZ41042.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KEZ41042.1 - 0.026 13.4 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 KEZ41042.1 - 0.078 12.7 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF466 PF04328.8 KEZ41042.1 - 0.39 10.5 4.4 0.21 11.4 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF466) AAA_21 PF13304.1 KEZ41042.1 - 0.51 10.2 0.0 0.51 10.2 0.0 3.0 2 1 1 3 3 3 0 AAA domain GST_N_2 PF13409.1 KEZ41043.1 - 1.2e-23 82.8 0.1 4.6e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ41043.1 - 4.6e-13 48.8 0.0 1.5e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEZ41043.1 - 8.5e-06 25.9 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEZ41043.1 - 8.8e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEZ41043.1 - 0.0089 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TPR_12 PF13424.1 KEZ41044.1 - 3.8e-65 215.7 9.8 2.7e-16 59.2 0.2 5.3 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ41044.1 - 8.9e-57 187.5 4.7 2e-11 43.4 0.0 8.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ41044.1 - 4.3e-18 64.7 0.4 4.3e-08 32.6 0.1 4.6 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 KEZ41044.1 - 1.9e-16 58.8 10.0 0.0037 16.8 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ41044.1 - 1.8e-11 44.3 0.2 3.5e-05 24.3 0.0 3.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ41044.1 - 1.3e-10 40.3 11.9 0.016 15.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ41044.1 - 1.6e-10 40.3 0.2 0.038 14.4 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ41044.1 - 8.2e-10 37.7 4.5 0.0097 15.6 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ41044.1 - 8.9e-10 37.8 0.0 1.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 KEZ41044.1 - 2.2e-07 30.5 0.0 0.12 12.6 0.0 5.6 6 0 0 6 6 4 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KEZ41044.1 - 3.4e-05 22.9 0.1 0.00014 20.9 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_8 PF13181.1 KEZ41044.1 - 0.00014 21.3 14.1 0.018 14.8 0.1 6.4 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ41044.1 - 0.00015 22.0 4.0 0.2 12.0 0.5 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ41044.1 - 0.00015 22.0 6.2 6.5 7.6 0.1 5.9 3 2 2 5 5 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 KEZ41044.1 - 0.0006 19.9 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Apc3 PF12895.2 KEZ41044.1 - 0.0013 18.8 0.1 0.4 10.8 0.0 3.7 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Rab5-bind PF09311.6 KEZ41044.1 - 0.012 15.5 0.0 26 4.6 0.0 3.4 1 1 3 4 4 4 0 Rabaptin-like protein TPR_6 PF13174.1 KEZ41044.1 - 0.024 15.0 3.9 7 7.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat 4HBT_3 PF13622.1 KEZ41045.1 - 5.4 6.6 7.5 7.5 6.2 5.2 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily PAT1 PF09770.4 KEZ41045.1 - 8.6 4.4 18.1 10 4.2 12.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RhoGAP PF00620.22 KEZ41046.1 - 4.2e-46 156.3 0.0 4.2e-46 156.3 0.0 2.6 3 1 0 3 3 3 1 RhoGAP domain LIM PF00412.17 KEZ41046.1 - 4e-14 52.4 16.9 4e-09 36.4 1.2 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.7 KEZ41046.1 - 0.23 10.8 7.3 5.1 6.5 0.5 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain zinc_ribbon_2 PF13240.1 KEZ41046.1 - 0.26 10.8 8.3 0.52 9.8 0.0 4.3 4 1 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 KEZ41046.1 - 0.38 10.7 17.7 0.37 10.7 1.0 4.2 4 0 0 4 4 4 0 Zinc ribbon domain CCDC155 PF14662.1 KEZ41046.1 - 0.8 9.2 21.7 1.3 8.5 14.7 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CLASP_N PF12348.3 KEZ41047.1 - 1.3e-127 423.8 1.7 7.1e-83 277.4 0.0 2.7 3 0 0 3 3 3 2 CLASP N terminal HEAT_2 PF13646.1 KEZ41047.1 - 9.8e-07 28.9 1.0 0.42 10.9 0.0 4.7 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 KEZ41047.1 - 0.018 15.0 0.0 8 6.8 0.0 4.4 4 1 1 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.2 KEZ41047.1 - 0.071 13.5 0.0 35 4.8 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Iso_dh PF00180.15 KEZ41048.1 - 2.1e-99 332.7 0.0 2.7e-99 332.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.20 KEZ41049.1 - 1.3e-24 86.7 0.0 2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KEZ41049.1 - 5.2e-11 41.9 11.9 1.9e-06 27.5 0.2 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 KEZ41049.1 - 7.2e-07 28.7 6.7 0.34 11.1 0.1 6.8 6 0 0 6 6 6 1 HEAT repeat Pkinase_Tyr PF07714.12 KEZ41049.1 - 0.00025 20.2 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 KEZ41049.1 - 0.00054 20.1 3.9 2.3 8.5 0.1 4.1 1 1 2 4 4 4 3 HEAT repeats APH PF01636.18 KEZ41049.1 - 0.0089 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family HEAT_EZ PF13513.1 KEZ41049.1 - 0.097 13.1 3.1 0.4 11.2 0.3 3.4 2 1 0 2 2 2 0 HEAT-like repeat Kinase-like PF14531.1 KEZ41049.1 - 0.12 11.3 0.0 0.28 10.1 0.0 1.6 1 0 0 1 1 1 0 Kinase-like SH3_9 PF14604.1 KEZ41050.1 - 2.3e-07 30.2 0.1 4.7e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ41050.1 - 0.0003 20.0 0.1 0.00066 19.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain DAP10 PF07213.6 KEZ41050.1 - 0.067 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 DAP10 membrane protein Gly-zipper_OmpA PF13436.1 KEZ41050.1 - 5.7 6.6 9.7 7 6.3 0.9 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF3782 PF12644.2 KEZ41052.1 - 0.38 10.5 6.9 4.2 7.2 3.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Occludin_ELL PF07303.8 KEZ41052.1 - 0.76 10.5 4.8 0.37 11.5 1.0 2.3 2 0 0 2 2 2 0 Occludin homology domain HSP70 PF00012.15 KEZ41053.1 - 5.6e-265 879.9 13.9 6.4e-265 879.7 9.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ41053.1 - 4.7e-15 54.9 1.1 3.6e-12 45.5 0.1 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KEZ41053.1 - 0.0005 19.7 0.1 0.0016 18.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.1 KEZ41053.1 - 0.067 12.9 2.4 0.15 11.8 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF2415 PF10313.4 KEZ41054.1 - 6.3e-13 48.1 0.0 4.6e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) eIF3g PF12353.3 KEZ41055.1 - 4.7e-45 152.6 4.3 7.4e-45 151.9 3.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KEZ41055.1 - 4.6e-16 58.2 0.1 1e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41055.1 - 2.1e-13 50.0 0.2 4.6e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41055.1 - 1.6e-08 34.2 0.6 2.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.8 KEZ41056.1 - 3.8e-53 178.0 18.2 5.7e-34 116.4 0.9 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase UPF0093 PF03653.8 KEZ41056.1 - 0.043 13.7 0.2 0.043 13.7 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) Lactonase PF10282.4 KEZ41057.1 - 6.9e-80 268.7 0.0 3.9e-79 266.2 0.0 1.8 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.13 KEZ41058.1 - 4e-09 36.2 7.9 4e-09 36.2 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ41058.1 - 3.7e-07 29.2 0.1 7e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain IBR PF01485.16 KEZ41060.1 - 5e-07 29.4 14.7 9.5e-07 28.6 10.2 1.4 1 0 0 1 1 1 1 IBR domain Daxx PF03344.10 KEZ41060.1 - 0.95 7.8 29.7 0.041 12.3 13.9 2.1 2 0 0 2 2 2 0 Daxx Family Prothymosin PF03247.9 KEZ41060.1 - 3.6 7.7 38.6 2.1 8.5 19.2 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family SAPS PF04499.10 KEZ41060.1 - 5.5 5.5 5.9 7.9 4.9 4.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop25 PF09805.4 KEZ41060.1 - 8.3 6.4 23.5 6.9 6.7 12.1 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF3433 PF11915.3 KEZ41061.1 - 2.5e-31 107.6 16.4 6.3e-21 74.3 0.7 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Cpn10 PF00166.16 KEZ41062.1 - 6e-27 93.4 0.0 6.8e-27 93.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 KEZ41063.1 - 5e-57 193.0 0.0 1e-56 191.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41063.1 - 5.1e-22 78.1 0.1 2.5e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEZ41063.1 - 0.0022 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEZ41063.1 - 0.11 11.4 0.0 0.29 10.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Ribosomal_L11_N PF03946.9 KEZ41064.1 - 3.3e-26 90.4 0.0 6.2e-26 89.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KEZ41064.1 - 4.9e-25 87.4 0.1 9e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain FTA2 PF13095.1 KEZ41065.1 - 1.7e-18 67.0 0.0 3.8e-18 65.8 0.0 1.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Sulf_transp PF04143.9 KEZ41066.1 - 5.1e-15 55.2 23.9 7.9e-11 41.8 5.9 4.6 6 0 0 6 6 6 2 Sulphur transport DUF4341 PF14241.1 KEZ41066.1 - 0.012 15.3 2.1 0.012 15.3 1.4 4.2 4 2 0 4 4 4 0 Domain of unknown function (DUF4341) Ribonuc_L-PSP PF01042.16 KEZ41067.1 - 5.6e-22 77.7 0.0 6.3e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SNF2_N PF00176.18 KEZ41068.1 - 4.7e-51 173.3 0.0 1.7e-43 148.5 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ41068.1 - 2.5e-12 46.4 0.0 5.2e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KEZ41068.1 - 3.9e-06 26.4 8.2 8.9e-06 25.3 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ41068.1 - 1.3e-05 24.9 8.4 2.4e-05 24.0 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KEZ41068.1 - 0.0003 20.3 10.3 0.00039 20.0 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ41068.1 - 0.0034 17.3 11.2 0.0095 15.9 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEZ41068.1 - 0.0042 16.7 2.9 0.012 15.3 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KEZ41068.1 - 0.012 15.2 8.3 0.012 15.2 5.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HDA2-3 PF11496.3 KEZ41068.1 - 0.019 13.8 1.2 0.087 11.6 0.1 2.4 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Rtf2 PF04641.7 KEZ41068.1 - 0.072 12.2 4.3 0.064 12.4 1.8 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_6 PF14835.1 KEZ41068.1 - 0.079 12.7 1.4 0.5 10.1 1.6 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KEZ41068.1 - 0.11 12.6 3.0 0.23 11.5 2.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KEZ41068.1 - 0.11 12.3 1.3 0.24 11.2 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEZ41068.1 - 0.13 11.8 7.4 0.11 12.0 3.6 2.2 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 KEZ41068.1 - 0.46 10.3 4.9 1.4 8.7 3.4 1.8 1 0 0 1 1 1 0 zinc-ribbons zf-C3HC4_4 PF15227.1 KEZ41068.1 - 0.85 9.5 7.9 1.6 8.6 5.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CDO_I PF05995.7 KEZ41069.1 - 2.4e-37 127.7 0.0 3e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KEZ41069.1 - 0.00062 19.1 0.2 0.00087 18.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) PI3_PI4_kinase PF00454.22 KEZ41070.1 - 5.4e-27 94.7 0.0 7.8e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SRRM_C PF15230.1 KEZ41071.1 - 6 7.0 7.8 0.63 10.1 1.1 2.2 2 1 1 3 3 3 0 Serine/arginine repetitive matrix protein C-terminus SNF2_N PF00176.18 KEZ41072.1 - 7.8e-67 225.1 0.0 1.1e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ41072.1 - 1.1e-07 31.5 0.0 2.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ41072.1 - 4.5e-07 29.5 0.0 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KEZ41072.1 - 4.7e-05 23.0 3.5 9.5e-05 22.0 2.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ41072.1 - 0.059 13.2 3.0 0.12 12.1 2.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KEZ41072.1 - 0.38 10.4 3.8 0.84 9.3 2.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Spc97_Spc98 PF04130.8 KEZ41073.1 - 5.6e-131 437.5 0.3 7.8e-131 437.0 0.2 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 KEZ41074.1 - 4e-56 189.3 0.1 5.2e-56 188.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEZ41074.1 - 1.1e-13 50.1 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 KEZ41074.1 - 0.033 13.8 0.1 0.76 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 KEZ41075.1 - 3.2e-15 55.6 0.1 1.7e-11 43.3 0.0 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41075.1 - 4.4e-08 32.8 11.9 8e-08 32.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ41075.1 - 1e-05 24.5 0.1 2.7e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ldl_recept_a PF00057.13 KEZ41075.1 - 0.15 11.9 5.8 0.27 11.1 4.0 1.4 1 0 0 1 1 1 0 Low-density lipoprotein receptor domain class A Asp_protease PF09668.5 KEZ41076.1 - 3.3e-59 197.8 0.3 4.9e-59 197.3 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KEZ41076.1 - 7.5e-13 48.8 0.1 1.5e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KEZ41076.1 - 2.8e-10 39.4 0.1 3.6e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family gag-asp_proteas PF13975.1 KEZ41076.1 - 3.9e-09 36.2 0.0 9.8e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 KEZ41076.1 - 8.2e-08 31.8 0.1 2.9e-07 30.1 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 KEZ41076.1 - 9.3e-07 28.8 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 KEZ41076.1 - 1.9e-05 24.4 0.2 8e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 KEZ41076.1 - 0.0001 21.9 0.1 0.00026 20.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEZ41076.1 - 0.033 14.4 0.1 0.094 12.9 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Acetyltransf_1 PF00583.19 KEZ41077.1 - 3.5e-08 33.3 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ41077.1 - 2.1e-06 27.8 0.0 4.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEZ41077.1 - 0.0064 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEZ41077.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein CRF-BP PF05428.6 KEZ41077.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) NOGCT PF08155.6 KEZ41078.1 - 2.6e-30 103.8 2.5 5.9e-30 102.7 1.7 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KEZ41078.1 - 5.8e-26 90.1 0.4 1.7e-25 88.6 0.2 1.9 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KEZ41078.1 - 1.1e-12 47.9 0.0 2.6e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ41078.1 - 2.9e-05 23.4 0.0 7.9e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KEZ41078.1 - 0.0062 17.0 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 KEZ41078.1 - 0.024 14.4 0.1 2.4 7.9 0.0 2.9 1 1 1 2 2 2 0 Dynamin family PPV_E1_C PF00519.12 KEZ41078.1 - 0.057 12.0 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DUF4648 PF15505.1 KEZ41078.1 - 0.14 12.3 2.8 0.18 12.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4648) DNA_pol_viral_N PF00242.12 KEZ41078.1 - 1.9 7.3 5.1 4.6 6.1 3.1 1.8 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain GDI PF00996.13 KEZ41079.1 - 5.9e-182 604.8 0.0 7.2e-182 604.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor MRP-L47 PF06984.8 KEZ41080.1 - 4.3e-23 81.0 0.2 4.3e-23 81.0 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) RFXA_RFXANK_bdg PF15289.1 KEZ41080.1 - 0.18 12.0 0.9 0.38 10.9 0.6 1.5 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Fungal_trans PF04082.13 KEZ41081.1 - 5.1e-13 48.4 0.1 9.1e-13 47.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KEZ41081.1 - 1.3e-07 31.5 8.3 5.6e-06 26.3 1.0 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEZ41081.1 - 1.6e-06 28.0 14.2 0.0015 18.6 4.3 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KEZ41081.1 - 0.0035 17.4 3.1 0.0068 16.5 2.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KEZ41081.1 - 0.0046 17.2 16.8 0.051 13.9 4.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KEZ41081.1 - 0.68 10.1 5.9 8.1 6.7 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KEZ41081.1 - 0.68 9.7 8.1 0.97 9.2 1.4 2.4 1 1 1 2 2 2 0 BED zinc finger Peptidase_S64 PF08192.6 KEZ41083.1 - 0.0085 14.4 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 KEZ41083.1 - 0.021 14.7 0.1 0.14 12.1 0.1 2.1 1 1 0 1 1 1 0 Trypsin-like peptidase domain Syd PF07348.7 KEZ41083.1 - 0.094 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Syd protein (SUKH-2) DUF500 PF04366.7 KEZ41084.1 - 2e-25 88.6 0.0 3.5e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) TFIIA PF03153.8 KEZ41084.1 - 2.7 7.8 18.3 0.045 13.6 6.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Actin PF00022.14 KEZ41085.1 - 2e-16 59.4 0.1 3.6e-12 45.4 0.0 3.2 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 KEZ41085.1 - 0.001 17.7 0.0 0.64 8.5 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FA_desaturase PF00487.19 KEZ41086.1 - 7.2e-16 58.4 7.3 7.2e-16 58.4 5.0 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KEZ41086.1 - 2.3e-13 49.7 0.1 5.7e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 KEZ41087.1 - 1.1e-09 37.8 0.0 2.2e-08 33.5 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41087.1 - 4e-09 35.9 0.0 3.6e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.8 KEZ41088.1 - 1e-62 211.1 0.0 1.8e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KEZ41088.1 - 9.1e-36 123.4 0.0 2.2e-35 122.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KEZ41088.1 - 6.5e-21 74.9 0.0 1.7e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KEZ41088.1 - 9e-08 31.6 0.0 2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KEZ41088.1 - 4.5e-07 29.6 0.0 9.9e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEZ41088.1 - 1.7e-06 28.0 0.0 5.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEZ41088.1 - 2.2e-05 24.5 0.0 0.00042 20.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KEZ41088.1 - 4.4e-05 22.3 0.0 8.1e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KEZ41088.1 - 9e-05 23.2 0.3 0.00048 20.9 0.0 2.4 3 0 0 3 3 1 1 AAA domain RuvB_N PF05496.7 KEZ41088.1 - 0.00026 20.1 0.0 0.0011 18.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEZ41088.1 - 0.00074 19.5 1.8 0.0061 16.5 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.1 KEZ41088.1 - 0.0019 18.4 1.2 0.033 14.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 KEZ41088.1 - 0.017 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEZ41088.1 - 0.033 13.6 0.1 0.091 12.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KEZ41088.1 - 0.035 14.2 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 KEZ41088.1 - 0.046 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KEZ41088.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KEZ41088.1 - 0.073 12.7 0.1 1 9.0 0.0 2.6 2 1 1 3 3 3 0 NTPase AAA_25 PF13481.1 KEZ41088.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.4 KEZ41088.1 - 1.4 8.8 7.7 0.22 11.4 0.4 2.9 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein Med21 PF11221.3 KEZ41089.1 - 2.6e-42 144.2 7.0 2.8e-42 144.0 4.9 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TMCO5 PF14992.1 KEZ41089.1 - 0.0083 15.2 4.8 0.0091 15.1 3.3 1.1 1 0 0 1 1 1 1 TMCO5 family Med9 PF07544.8 KEZ41089.1 - 0.0098 15.6 1.5 0.0098 15.6 1.0 2.5 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Spore_III_AB PF09548.5 KEZ41089.1 - 0.026 14.2 1.7 0.039 13.6 1.2 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TMF_DNA_bd PF12329.3 KEZ41089.1 - 0.052 13.3 9.3 0.041 13.6 4.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 KEZ41089.1 - 0.061 12.5 5.8 1.9 7.6 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HTH_5 PF01022.15 KEZ41089.1 - 0.075 12.7 0.5 6.2 6.5 0.2 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HemX PF04375.9 KEZ41089.1 - 0.17 10.4 2.7 0.42 9.1 0.5 2.0 2 0 0 2 2 2 0 HemX DUF3802 PF12290.3 KEZ41089.1 - 0.19 12.0 1.1 0.38 11.0 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3802) APG6 PF04111.7 KEZ41089.1 - 2.6 7.0 7.1 2.8 6.9 2.9 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 M PF02370.11 KEZ41089.1 - 6.4 7.4 9.4 5.1 7.8 1.9 3.0 2 0 0 2 2 2 0 M protein repeat IncA PF04156.9 KEZ41089.1 - 8.1 5.9 11.5 10 5.6 8.0 1.4 1 1 0 1 1 1 0 IncA protein HAD_2 PF13419.1 KEZ41090.1 - 4.1e-27 95.5 0.2 6.6e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEZ41090.1 - 1.5e-05 25.5 0.0 4.5e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ41090.1 - 0.00054 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NPH3 PF03000.9 KEZ41090.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 NPH3 family KH_1 PF00013.24 KEZ41091.1 - 7e-25 86.4 1.6 1.3e-07 31.1 0.2 7.6 8 0 0 8 8 8 5 KH domain KH_3 PF13014.1 KEZ41091.1 - 1.2e-21 75.8 5.3 0.0001 21.8 0.3 6.3 6 0 0 6 6 6 5 KH domain OEP PF02321.13 KEZ41091.1 - 0.14 11.7 0.1 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein Eaf7 PF07904.8 KEZ41092.1 - 1.6e-22 79.3 0.1 1.6e-22 79.3 0.1 2.6 3 0 0 3 3 3 1 Chromatin modification-related protein EAF7 DUF2890 PF11081.3 KEZ41092.1 - 1.8 8.6 26.2 4.3 7.3 7.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Spt5_N PF11942.3 KEZ41092.1 - 2.2 8.9 27.1 1.1 9.9 4.3 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Trypan_PARP PF05887.6 KEZ41092.1 - 2.7 7.8 30.5 3.9 7.2 9.1 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4554 PF15091.1 KEZ41092.1 - 3.3 6.3 6.0 4.9 5.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Spc97_Spc98 PF04130.8 KEZ41093.1 - 1.6e-70 237.9 0.0 2.1e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Hist_deacetyl PF00850.14 KEZ41094.1 - 1.2e-62 212.0 0.2 1.7e-62 211.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PHP PF02811.14 KEZ41095.1 - 2.5e-10 40.3 0.0 3.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 PHP domain MOSC PF03473.12 KEZ41096.1 - 1.4e-14 53.6 0.0 3.2e-14 52.5 0.0 1.6 1 1 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KEZ41096.1 - 9.6e-14 51.1 0.0 1.9e-12 46.9 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MotB_plug PF13677.1 KEZ41096.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB His_Phos_2 PF00328.17 KEZ41097.1 - 4.4e-122 407.7 2.9 7.6e-122 406.9 2.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KEZ41097.1 - 3.5e-05 23.3 0.0 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 KEZ41098.1 - 4.4e-83 278.0 0.0 6.3e-83 277.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KEZ41098.1 - 9.4e-27 91.9 20.9 1.8e-07 30.7 0.1 8.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KEZ41098.1 - 3.9e-06 25.3 0.1 0.013 13.6 0.0 3.2 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KEZ41098.1 - 0.0001 20.7 0.0 0.0002 19.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KEZ41098.1 - 0.0082 14.9 0.0 3 6.4 0.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like DASH_Ask1 PF08655.5 KEZ41099.1 - 4.4e-33 112.9 0.1 7.5e-33 112.1 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 LXG PF04740.7 KEZ41099.1 - 0.019 14.7 1.2 0.042 13.6 0.8 1.6 1 1 0 1 1 1 0 LXG domain of WXG superfamily YqfQ PF14181.1 KEZ41099.1 - 0.13 12.3 1.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 YqfQ-like protein Nol1_Nop2_Fmu PF01189.12 KEZ41100.1 - 7.3e-32 110.8 0.0 3e-20 72.7 0.0 3.5 3 0 0 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KEZ41100.1 - 3.6e-05 23.7 0.0 7.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ41100.1 - 0.0087 16.0 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Mitofilin PF09731.4 KEZ41102.1 - 0.14 10.8 56.2 0.057 12.0 30.9 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Baculo_PEP_C PF04513.7 KEZ41102.1 - 3.6 7.4 10.7 10 5.9 0.6 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 KEZ41102.1 - 8.5 5.3 53.3 1.1 8.2 16.6 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 UPF0242 PF06785.6 KEZ41102.1 - 8.7 4.8 19.7 1.2 7.7 10.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) RNA_pol_Rpb5_C PF01191.14 KEZ41103.1 - 1.1e-34 117.8 0.3 2.4e-34 116.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KEZ41103.1 - 3.2e-27 94.7 0.1 5.2e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KEZ41103.1 - 0.0022 17.7 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Restriction endonuclease Epimerase PF01370.16 KEZ41105.1 - 1.1e-08 34.8 0.1 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEZ41105.1 - 2.8e-07 30.8 0.0 6.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KEZ41105.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ41105.1 - 0.0013 18.8 0.0 0.0045 17.0 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KEZ41105.1 - 0.002 17.1 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KEZ41105.1 - 0.024 13.5 0.0 0.12 11.2 0.0 2.2 2 1 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.14 KEZ41105.1 - 0.043 12.5 0.0 0.57 8.8 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KEZ41105.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TFCD_C PF12612.3 KEZ41106.1 - 4.1e-28 98.1 3.5 1.1e-27 96.7 1.2 2.5 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KEZ41106.1 - 0.0036 17.2 4.4 0.87 9.8 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat ABC_tran PF00005.22 KEZ41107.1 - 7.8e-34 116.9 1.4 7e-17 62.0 0.0 3.6 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ41107.1 - 2.9e-26 92.5 22.3 1.6e-14 54.0 7.4 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_23 PF13476.1 KEZ41107.1 - 5.7e-06 26.8 7.8 2.2e-05 24.8 0.4 3.0 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KEZ41107.1 - 2.6e-05 24.3 0.1 0.75 9.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KEZ41107.1 - 4.1e-05 23.0 1.9 0.17 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEZ41107.1 - 0.0001 21.8 0.7 0.62 9.4 0.0 3.0 3 0 0 3 3 3 2 FtsK/SpoIIIE family DUF258 PF03193.11 KEZ41107.1 - 0.0003 20.0 0.1 0.015 14.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 KEZ41107.1 - 0.00045 19.5 9.3 0.69 9.1 0.1 4.0 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KEZ41107.1 - 0.00048 19.5 0.1 0.029 13.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KEZ41107.1 - 0.002 18.0 0.0 1.3 8.9 0.0 3.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KEZ41107.1 - 0.0044 17.0 0.2 0.25 11.3 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KEZ41107.1 - 0.006 17.0 1.9 0.59 10.6 0.0 3.4 3 0 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 KEZ41107.1 - 0.0061 16.7 0.6 0.88 9.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KEZ41107.1 - 0.012 15.0 0.1 0.61 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 KEZ41107.1 - 0.021 14.5 1.3 0.28 10.9 0.1 3.2 3 0 0 3 3 3 0 Part of AAA domain T2SE PF00437.15 KEZ41107.1 - 0.041 12.7 0.0 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 KEZ41107.1 - 0.067 12.1 0.1 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KEZ41107.1 - 0.077 12.6 0.5 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KEZ41107.1 - 0.16 11.9 0.5 26 4.7 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEZ41107.1 - 0.18 11.5 3.7 0.48 10.2 0.0 2.9 3 0 0 3 3 3 0 Dynamin family AAA_15 PF13175.1 KEZ41107.1 - 0.19 10.7 0.0 0.43 9.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 KEZ41107.1 - 0.19 11.0 0.9 1.5 8.0 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_17 PF13207.1 KEZ41107.1 - 0.33 11.7 4.3 15 6.4 0.4 2.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KEZ41107.1 - 0.53 9.8 3.7 3.1 7.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KEZ41107.1 - 0.76 10.0 3.2 10 6.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 KEZ41107.1 - 2.6 7.7 7.9 0.77 9.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 Glycos_transf_2 PF00535.21 KEZ41108.1 - 1.5e-24 86.5 0.0 2.7e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEZ41108.1 - 1.4e-12 47.9 0.2 1.1e-08 35.1 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KEZ41108.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 SMK-1 PF04802.10 KEZ41110.1 - 4.6e-77 257.9 0.4 4.6e-77 257.9 0.3 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 AAA PF00004.24 KEZ41111.1 - 1.1e-49 168.0 0.0 2.3e-36 124.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEZ41111.1 - 2e-07 30.2 0.0 5e-05 22.4 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEZ41111.1 - 4.2e-07 30.1 2.5 0.0053 16.7 0.0 4.0 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.9 KEZ41111.1 - 2.5e-06 27.2 0.0 0.037 13.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEZ41111.1 - 7.8e-06 26.7 0.1 0.15 12.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KEZ41111.1 - 9.8e-06 25.6 0.0 0.062 13.4 0.0 2.9 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.1 KEZ41111.1 - 0.00022 21.1 0.0 0.49 10.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KEZ41111.1 - 0.00026 20.9 0.4 0.27 11.1 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KEZ41111.1 - 0.00034 20.0 0.1 0.12 11.7 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 KEZ41111.1 - 0.00038 20.5 0.5 0.29 11.2 0.1 3.7 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.1 KEZ41111.1 - 0.0011 18.9 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KEZ41111.1 - 0.0015 17.9 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 KEZ41111.1 - 0.0034 17.1 0.0 0.099 12.4 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KEZ41111.1 - 0.01 15.8 0.0 0.62 10.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 KEZ41111.1 - 0.025 14.1 0.0 7.8 6.1 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KEZ41111.1 - 0.036 13.6 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KEZ41111.1 - 0.055 12.1 0.0 0.087 11.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Torsin PF06309.6 KEZ41111.1 - 0.098 12.5 0.0 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Torsin KAP_NTPase PF07693.9 KEZ41111.1 - 0.22 10.4 0.2 13 4.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.7 KEZ41111.1 - 0.23 11.0 1.8 3.7 7.1 0.1 3.1 2 1 1 3 3 3 0 NACHT domain NCA2 PF08637.5 KEZ41112.1 - 5.7e-77 258.4 0.5 9.6e-77 257.7 0.3 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 KEZ41112.1 - 0.15 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Ras PF00071.17 KEZ41113.1 - 5e-65 217.8 0.0 5.9e-65 217.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ41113.1 - 8e-20 71.5 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ41113.1 - 5.7e-13 48.4 0.0 7.1e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KEZ41113.1 - 2.9e-06 26.8 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEZ41113.1 - 6.9e-06 25.3 0.0 9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEZ41113.1 - 0.0047 16.8 0.0 0.0069 16.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEZ41113.1 - 0.033 13.4 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KEZ41113.1 - 0.034 13.3 0.0 0.16 11.1 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 KEZ41113.1 - 0.045 13.0 0.0 0.23 10.7 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 KEZ41113.1 - 0.059 13.5 0.0 4.9 7.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KEZ41113.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KEZ41113.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 KEZ41113.1 - 0.15 10.7 0.5 16 4.0 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit FA_hydroxylase PF04116.8 KEZ41115.1 - 3e-14 53.4 16.7 3e-14 53.4 11.6 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily bZIP_1 PF00170.16 KEZ41116.1 - 7e-07 29.1 13.0 3.5e-06 26.8 9.0 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ41116.1 - 4.3 7.2 11.9 23 4.9 8.2 2.0 1 1 0 1 1 1 0 Basic region leucine zipper Actin PF00022.14 KEZ41117.1 - 1e-60 205.2 0.0 1.7e-59 201.2 0.0 2.1 1 1 0 1 1 1 1 Actin Got1 PF04178.7 KEZ41118.1 - 9.3e-19 67.6 12.3 1.1e-18 67.4 8.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 KEZ41118.1 - 0.71 9.5 8.3 0.069 12.8 2.0 2.1 2 1 0 2 2 2 0 YrhK-like protein Profilin PF00235.14 KEZ41119.1 - 7.9e-41 138.9 0.0 8.9e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 Profilin FIST PF08495.5 KEZ41119.1 - 0.045 12.8 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 FIST N domain Sec63 PF02889.11 KEZ41120.1 - 4.9e-154 512.1 0.0 2e-97 326.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEZ41120.1 - 9.6e-54 181.3 0.2 3.2e-28 98.3 0.2 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KEZ41120.1 - 2.6e-15 56.7 0.0 3e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEZ41120.1 - 2.9e-15 55.8 0.0 2.5e-06 27.2 0.0 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEZ41120.1 - 5e-08 33.1 0.0 0.02 15.0 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEZ41120.1 - 2.7e-06 27.0 0.9 0.019 14.6 0.0 3.6 4 0 0 4 4 4 2 Part of AAA domain SNF2_N PF00176.18 KEZ41120.1 - 6.7e-06 25.1 0.3 0.062 12.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_30 PF13604.1 KEZ41120.1 - 0.00014 21.5 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KEZ41120.1 - 0.0037 17.4 0.1 2.1 8.5 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEZ41120.1 - 0.022 14.1 0.1 16 4.8 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.11 KEZ41120.1 - 0.058 12.6 0.0 2.5 7.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 KEZ41120.1 - 0.067 12.6 0.0 16 4.8 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KEZ41120.1 - 0.069 12.6 0.0 5.8 6.3 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF1071 PF06378.6 KEZ41120.1 - 0.26 10.4 0.0 0.62 9.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Ras PF00071.17 KEZ41121.1 - 1.6e-40 138.1 0.0 3e-38 130.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KEZ41121.1 - 1.6e-18 67.3 0.0 2.4e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ41121.1 - 8.3e-11 41.4 0.0 1.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEZ41121.1 - 0.0049 16.8 0.0 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KEZ41121.1 - 0.0076 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KEZ41121.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KEZ41121.1 - 0.064 13.3 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KEZ41121.1 - 0.12 11.8 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KEZ41121.1 - 0.12 11.9 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEZ41121.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KEZ41121.1 - 0.15 12.0 0.6 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF2411 PF10304.4 KEZ41121.1 - 0.26 10.8 2.5 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2411) FMN_dh PF01070.13 KEZ41122.1 - 6.1e-121 403.6 0.1 7.8e-121 403.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEZ41122.1 - 2.3e-23 81.7 0.0 4.6e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KEZ41122.1 - 2.5e-08 33.2 0.0 4.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEZ41122.1 - 0.00068 18.6 0.4 0.0042 16.0 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KEZ41122.1 - 0.001 18.2 0.2 0.0018 17.4 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 KEZ41122.1 - 0.026 13.8 1.2 2.3 7.4 0.1 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein BRO1 PF03097.13 KEZ41123.1 - 2.6e-131 437.8 1.0 2.6e-131 437.8 0.7 1.8 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KEZ41123.1 - 5.9e-88 294.6 20.9 1.1e-87 293.8 14.5 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3012 PF11216.3 KEZ41123.1 - 0.19 11.4 2.3 1 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) DUF257 PF03192.8 KEZ41123.1 - 0.27 10.4 1.5 0.45 9.7 0.4 1.9 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 DUF948 PF06103.6 KEZ41123.1 - 1.1 9.1 3.9 3.2 7.6 0.4 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CTDII PF01556.13 KEZ41124.1 - 3.8e-28 97.2 1.1 3.5e-21 74.8 0.2 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KEZ41124.1 - 8.3e-26 89.5 2.2 1.8e-25 88.4 1.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KEZ41124.1 - 5.9e-10 39.0 20.1 1e-09 38.2 13.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEZ41124.1 - 0.99 9.1 7.5 74 3.0 5.1 2.8 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Fungal_trans PF04082.13 KEZ41125.1 - 6.7e-63 211.9 0.0 9.3e-63 211.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 KEZ41125.1 - 1.8e-05 24.7 14.0 0.0002 21.4 1.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ41125.1 - 0.00038 20.6 2.2 0.00038 20.6 1.5 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEZ41125.1 - 0.085 13.1 15.2 0.074 13.3 2.8 3.0 3 0 0 3 3 3 0 Zinc-finger double domain F-box-like PF12937.2 KEZ41126.1 - 3.3e-11 42.7 0.0 7.8e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ41126.1 - 2.4e-06 27.0 0.1 7e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain 4HBT PF03061.17 KEZ41127.1 - 7.2e-13 48.4 0.1 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KEZ41127.1 - 1.8e-05 24.6 1.1 3.7e-05 23.5 0.1 1.9 1 1 1 2 2 2 1 Thioesterase-like superfamily Glyco_hydro_16 PF00722.16 KEZ41128.1 - 7.1e-07 28.6 0.3 1.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 ABC_tran PF00005.22 KEZ41129.1 - 3.1e-43 147.3 3.9 1e-20 74.3 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 KEZ41129.1 - 1.7e-12 47.9 6.7 0.00083 19.4 0.0 4.8 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 KEZ41129.1 - 1.1e-10 41.1 0.4 0.087 12.0 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEZ41129.1 - 6.2e-09 35.2 0.4 5.7e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEZ41129.1 - 9.8e-08 31.9 0.4 0.017 15.0 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase ABC_tran_2 PF12848.2 KEZ41129.1 - 3.3e-07 30.0 3.9 1.1e-06 28.3 2.7 1.9 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 KEZ41129.1 - 3.9e-07 30.9 0.1 0.037 14.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ41129.1 - 1.5e-06 28.3 6.3 0.011 15.7 1.8 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KEZ41129.1 - 2.7e-06 27.5 0.8 0.2 11.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KEZ41129.1 - 3.2e-06 27.1 0.2 0.016 15.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KEZ41129.1 - 4.4e-06 27.1 0.0 0.03 14.8 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KEZ41129.1 - 2e-05 23.8 0.2 0.21 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 KEZ41129.1 - 5.4e-05 22.0 1.9 0.0059 15.4 0.1 2.3 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 KEZ41129.1 - 6.6e-05 22.6 0.0 0.013 15.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KEZ41129.1 - 8.8e-05 22.4 0.1 0.78 9.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KEZ41129.1 - 0.0001 21.8 0.5 0.28 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 KEZ41129.1 - 0.00015 21.7 7.3 0.091 12.5 0.0 3.1 4 0 0 4 4 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 KEZ41129.1 - 0.00019 21.7 2.7 0.46 10.7 0.0 3.3 4 0 0 4 4 2 2 AAA domain MobB PF03205.9 KEZ41129.1 - 0.00035 20.3 0.4 1.2 8.8 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KEZ41129.1 - 0.00036 20.3 0.2 0.29 10.8 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase Dynamin_N PF00350.18 KEZ41129.1 - 0.00069 19.4 0.5 0.9 9.3 0.0 2.8 3 0 0 3 3 2 2 Dynamin family AAA_14 PF13173.1 KEZ41129.1 - 0.0015 18.3 0.5 2.3 8.1 0.0 3.8 5 0 0 5 5 4 1 AAA domain AAA PF00004.24 KEZ41129.1 - 0.0027 17.9 0.0 1.2 9.2 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEZ41129.1 - 0.0027 16.6 0.3 2.2 7.1 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_23 PF13476.1 KEZ41129.1 - 0.0035 17.6 12.0 0.057 13.7 1.3 3.4 3 1 0 3 3 3 2 AAA domain Arf PF00025.16 KEZ41129.1 - 0.0035 16.5 0.6 0.19 10.9 0.1 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KEZ41129.1 - 0.004 17.3 0.1 0.88 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.13 KEZ41129.1 - 0.0042 16.6 0.0 3.8 6.9 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.12 KEZ41129.1 - 0.0055 16.1 0.1 1.6 8.0 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase AAA_15 PF13175.1 KEZ41129.1 - 0.0084 15.1 4.6 0.25 10.3 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain ATP-synt_ab PF00006.20 KEZ41129.1 - 0.0085 15.6 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KEZ41129.1 - 0.0094 15.3 0.1 0.36 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEZ41129.1 - 0.016 14.6 1.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KEZ41129.1 - 0.023 14.4 0.7 2.6 7.7 0.0 2.9 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.7 KEZ41129.1 - 0.023 13.7 0.3 5 6.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KEZ41129.1 - 0.025 14.0 3.6 0.071 12.5 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KEZ41129.1 - 0.028 14.1 0.9 0.93 9.2 0.0 3.5 4 0 0 4 4 4 0 Part of AAA domain AAA_13 PF13166.1 KEZ41129.1 - 0.036 12.5 4.7 1.4 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KEZ41129.1 - 0.066 12.6 0.2 2.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KEZ41129.1 - 0.067 12.9 0.2 2.8 7.6 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 KEZ41129.1 - 0.1 11.4 5.2 2.8 6.7 0.0 3.3 3 1 0 3 3 3 0 NB-ARC domain UPF0079 PF02367.12 KEZ41129.1 - 0.12 12.0 0.4 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF3437 PF11919.3 KEZ41130.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) adh_short PF00106.20 KEZ41131.1 - 2.6e-64 216.1 7.1 7.6e-32 110.5 0.9 2.3 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KEZ41131.1 - 4.7e-32 109.9 0.0 1.1e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KEZ41131.1 - 2.3e-31 108.8 1.7 1e-15 57.8 0.1 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 KEZ41131.1 - 1.9e-05 24.2 1.2 0.0097 15.3 0.1 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KEZ41131.1 - 0.00039 19.5 0.9 0.0041 16.2 0.2 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4397 PF14344.1 KEZ41131.1 - 0.038 14.3 0.2 4.1 7.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4397) Eno-Rase_NADH_b PF12242.3 KEZ41131.1 - 0.22 11.3 2.6 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KEZ41131.1 - 0.23 11.0 8.7 2.5 7.7 0.8 3.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glucodextran_B PF09136.5 KEZ41131.1 - 5.1 7.3 8.5 0.11 12.6 0.2 2.5 3 0 0 3 3 3 0 Glucodextranase, domain B Acetyltransf_1 PF00583.19 KEZ41132.1 - 0.0022 18.0 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Xpo1 PF08389.7 KEZ41133.1 - 1.3e-26 93.2 2.4 1.3e-25 90.0 0.1 3.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KEZ41133.1 - 6e-06 26.0 0.0 2.5e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KEZ41133.1 - 0.0042 15.4 0.4 0.57 8.4 0.1 2.6 2 0 0 2 2 2 2 Adaptin N terminal region RVT_N PF13655.1 KEZ41133.1 - 0.019 15.0 0.1 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase Prenyltrans_1 PF13243.1 KEZ41133.1 - 0.16 11.9 0.0 0.52 10.3 0.0 1.9 1 0 0 1 1 1 0 Prenyltransferase-like DUF2130 PF09903.4 KEZ41133.1 - 0.2 10.4 0.0 1 8.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) 5-FTHF_cyc-lig PF01812.15 KEZ41134.1 - 6.8e-29 100.9 0.0 8.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.10 KEZ41135.1 - 1e-203 678.2 37.7 1.2e-203 678.0 26.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein APH PF01636.18 KEZ41136.1 - 1.8e-11 44.2 0.0 2.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ41136.1 - 0.00013 21.6 0.0 0.00033 20.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KEZ41137.1 - 5.6e-39 133.4 0.0 9.1e-27 93.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 KEZ41137.1 - 1.2e-31 108.6 0.0 2.5e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KEZ41137.1 - 5.5e-06 26.2 0.1 0.0058 16.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KEZ41137.1 - 0.001 18.1 0.0 0.017 14.1 0.0 2.4 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family PC_rep PF01851.17 KEZ41138.1 - 5.3e-21 73.6 10.6 1.1e-05 25.4 0.0 9.0 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KEZ41138.1 - 8.6e-07 29.1 0.5 0.059 13.6 0.0 4.5 3 1 2 5 5 5 3 HEAT repeats Zn_clus PF00172.13 KEZ41139.1 - 3.2e-06 26.9 10.8 4.7e-06 26.3 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lon_C PF05362.8 KEZ41140.1 - 5.8e-66 221.7 0.1 1.2e-65 220.6 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KEZ41140.1 - 2.1e-23 82.9 0.0 1.7e-21 76.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KEZ41140.1 - 7e-19 68.3 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KEZ41140.1 - 1.2e-08 34.7 0.0 3.5e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KEZ41140.1 - 8.7e-08 31.7 0.0 2.1e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 KEZ41140.1 - 1.8e-05 24.8 0.0 4.8e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KEZ41140.1 - 6.7e-05 23.6 0.0 0.00024 21.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEZ41140.1 - 6.7e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 KEZ41140.1 - 9.5e-05 22.0 0.0 0.00029 20.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEZ41140.1 - 0.00023 20.2 0.1 0.00065 18.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEZ41140.1 - 0.00042 20.0 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 KEZ41140.1 - 0.00053 19.9 0.0 0.002 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEZ41140.1 - 0.0011 19.1 0.0 0.017 15.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEZ41140.1 - 0.0024 16.9 0.0 0.0045 16.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 KEZ41140.1 - 0.0047 15.6 0.5 0.031 13.0 0.1 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 KEZ41140.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KEZ41140.1 - 0.0085 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 KEZ41140.1 - 0.0087 16.2 0.0 0.07 13.3 0.0 2.6 3 0 0 3 3 1 1 RNA helicase AAA_18 PF13238.1 KEZ41140.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEZ41140.1 - 0.011 15.4 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 KEZ41140.1 - 0.018 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEZ41140.1 - 0.024 14.9 10.1 0.062 13.6 0.0 3.2 2 1 1 3 3 2 0 AAA domain AAA_25 PF13481.1 KEZ41140.1 - 0.031 13.6 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEZ41140.1 - 0.052 12.6 0.0 0.14 11.2 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KEZ41140.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KEZ41140.1 - 0.068 12.8 0.0 0.27 10.9 0.0 2.1 1 1 1 2 2 2 0 NTPase AAA_24 PF13479.1 KEZ41140.1 - 0.073 12.6 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEZ41140.1 - 0.087 12.3 0.2 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RPA_C PF08784.6 KEZ41141.1 - 4.3e-20 72.0 1.3 8.4e-20 71.0 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KEZ41141.1 - 4.6e-05 23.1 0.5 0.00014 21.6 0.2 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Acetyltransf_7 PF13508.1 KEZ41142.1 - 1.3e-12 47.7 0.0 2.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEZ41142.1 - 3.1e-08 33.5 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KEZ41142.1 - 3.8e-08 33.2 0.0 6.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEZ41142.1 - 6.4e-05 23.0 0.0 0.00017 21.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEZ41142.1 - 0.00057 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KEZ41142.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NUDIX PF00293.23 KEZ41143.1 - 2.8e-29 101.4 0.0 5.6e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.13 KEZ41144.1 - 7.1e-55 185.0 28.5 4.8e-29 101.0 5.3 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KEZ41144.1 - 2.3e-05 24.2 10.2 2.3e-05 24.2 7.1 3.8 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain LSM PF01423.17 KEZ41145.1 - 1.6e-14 53.1 0.0 2.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain GRP PF07172.6 KEZ41145.1 - 1.5 9.3 17.6 2.2 8.8 12.2 1.2 1 0 0 1 1 1 0 Glycine rich protein family RAM PF15320.1 KEZ41145.1 - 4.7 7.5 8.4 6.8 7.0 5.8 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein MFS_1 PF07690.11 KEZ41146.1 - 8.8e-25 87.1 44.6 3.1e-24 85.3 19.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily HATPase_c_3 PF13589.1 KEZ41146.1 - 0.048 13.3 0.6 13 5.4 0.0 2.2 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAM176 PF14851.1 KEZ41146.1 - 0.43 10.2 2.4 0.86 9.2 1.7 1.4 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 KEZ41146.1 - 1.9 8.0 13.2 3.2 7.2 9.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin SDA1 PF05285.7 KEZ41146.1 - 2.1 7.5 9.7 3.2 6.9 6.7 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 KEZ41146.1 - 2.2 7.8 7.8 4.5 6.8 5.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KEZ41146.1 - 2.5 8.4 16.9 6.6 7.1 11.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Homeobox_KN PF05920.6 KEZ41147.1 - 1.5e-14 53.4 1.0 1.5e-14 53.4 0.7 2.5 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.11 KEZ41147.1 - 5.9e-12 45.2 2.9 2.1e-06 27.4 0.1 3.9 3 1 0 3 3 3 2 Tc5 transposase DNA-binding domain zf-C2H2 PF00096.21 KEZ41147.1 - 8.2e-06 25.8 11.9 0.013 15.8 2.6 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type Homeobox PF00046.24 KEZ41147.1 - 2e-05 24.1 0.4 6.8e-05 22.4 0.3 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KEZ41147.1 - 0.00042 20.4 14.9 0.013 15.7 2.6 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 KEZ41147.1 - 2.3 8.5 6.6 1.2e+02 3.0 1.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type MTHFR PF02219.12 KEZ41148.1 - 2e-109 365.1 0.0 2.7e-109 364.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RRM_5 PF13893.1 KEZ41149.1 - 6.6e-10 38.7 0.1 3.6e-08 33.1 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41149.1 - 2.9e-09 36.7 0.0 7e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ41149.1 - 3.3e-08 33.0 0.2 1.6e-07 30.8 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KEZ41149.1 - 2e-06 27.8 0.2 4.2e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 KEZ41149.1 - 3.3e-05 23.5 0.0 0.0047 16.6 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 KEZ41149.1 - 4.4e-05 23.0 2.3 9e-05 22.0 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U79_P34 PF03064.11 KEZ41149.1 - 0.92 8.9 6.2 0.36 10.3 2.3 1.7 2 0 0 2 2 2 0 HSV U79 / HCMV P34 GTP_EFTU PF00009.22 KEZ41150.1 - 2.2e-61 206.5 0.2 3.2e-61 206.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEZ41150.1 - 6.5e-38 128.9 0.0 2e-37 127.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KEZ41150.1 - 6.5e-22 77.2 0.0 1.6e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEZ41150.1 - 6.2e-12 45.4 0.0 6.2e-12 45.4 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KEZ41150.1 - 1e-11 44.4 0.0 3.3e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KEZ41150.1 - 7.9e-07 29.0 0.1 1.6e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sulfatase PF00884.18 KEZ41150.1 - 0.034 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Sulfatase Solute_trans_a PF03619.11 KEZ41152.1 - 6.4e-90 301.1 10.0 4.3e-89 298.4 7.0 1.9 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_92 PF07971.7 KEZ41153.1 - 7.3e-154 513.1 0.0 9.7e-154 512.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Fungal_trans PF04082.13 KEZ41154.1 - 1.9e-17 63.0 0.0 5e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Hep_59 PF07052.6 KEZ41154.1 - 0.079 13.3 0.0 8 6.8 0.0 2.4 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 MFS_1 PF07690.11 KEZ41155.1 - 1e-44 152.7 35.5 1e-44 152.7 24.6 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ41155.1 - 3.3e-13 49.0 22.9 1e-12 47.4 15.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KEZ41155.1 - 4.2e-05 21.8 12.6 0.0078 14.3 4.7 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Zn_clus PF00172.13 KEZ41156.1 - 0.014 15.3 7.0 0.03 14.2 4.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 KEZ41156.1 - 0.12 12.2 2.4 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Sec5 PF15469.1 KEZ41157.1 - 5e-34 117.6 0.0 2.2e-33 115.5 0.0 2.2 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 KEZ41157.1 - 0.00023 20.9 1.2 0.0016 18.2 0.1 2.7 2 0 0 2 2 2 1 Vps51/Vps67 LRR_9 PF14580.1 KEZ41158.1 - 8.7e-33 113.3 0.3 8.6e-21 74.2 0.0 2.5 2 1 1 3 3 3 2 Leucine-rich repeat DUF4349 PF14257.1 KEZ41158.1 - 0.00037 19.8 0.2 0.00051 19.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_4 PF12799.2 KEZ41158.1 - 0.0071 15.9 0.1 0.15 11.7 0.0 2.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ41158.1 - 0.06 13.1 0.3 1.1 9.1 0.0 2.4 1 1 2 3 3 3 0 Leucine rich repeat PspB PF06667.7 KEZ41158.1 - 0.23 11.4 2.6 0.33 10.9 1.2 1.7 2 0 0 2 2 2 0 Phage shock protein B CBFD_NFYB_HMF PF00808.18 KEZ41159.1 - 2e-12 46.9 0.2 3.8e-12 46.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 KEZ41160.1 - 5.8e-89 298.5 28.1 5.8e-89 298.5 19.5 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KEZ41160.1 - 1.6e-13 50.1 0.1 2.2e-05 24.1 0.0 2.8 2 0 0 2 2 2 2 CBS domain ASCH PF04266.9 KEZ41160.1 - 0.044 14.1 0.1 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 ASCH domain RAMP PF04901.8 KEZ41160.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Receptor activity modifying family EamA PF00892.15 KEZ41161.1 - 0.00016 21.6 2.2 0.00075 19.5 1.7 1.8 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 KEZ41161.1 - 0.0026 17.9 0.6 0.0043 17.2 0.4 1.3 1 0 0 1 1 1 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 KEZ41161.1 - 0.037 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 DUF998 PF06197.8 KEZ41161.1 - 0.63 9.3 7.9 0.3 10.3 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF998) AAA_22 PF13401.1 KEZ41162.1 - 3.6e-08 33.6 0.0 1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ41162.1 - 5.1e-08 33.1 0.2 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KEZ41162.1 - 1.5e-07 31.1 0.0 4.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 KEZ41162.1 - 0.00066 19.2 0.1 0.036 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 KEZ41162.1 - 0.00085 19.6 0.0 0.0035 17.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 KEZ41162.1 - 0.0062 16.8 0.2 0.15 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KEZ41162.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KEZ41162.1 - 0.03 13.1 0.0 0.066 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KEZ41162.1 - 0.059 14.1 0.2 0.9 10.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 KEZ41162.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 KEZ41162.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TFIIA_gamma_C PF02751.9 KEZ41163.1 - 7.1e-26 89.7 0.7 9.6e-26 89.3 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KEZ41163.1 - 7.7e-26 89.4 0.3 1.1e-25 88.9 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 KEZ41164.1 - 7.4e-25 86.6 29.9 5.1e-17 61.5 5.0 3.0 3 0 0 3 3 3 2 ATP synthase subunit C MpPF26 PF07666.6 KEZ41164.1 - 0.088 12.7 2.0 0.29 11.0 0.2 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF2427 PF10348.4 KEZ41164.1 - 0.12 11.9 1.6 3.8 7.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) MoCF_biosynth PF00994.19 KEZ41165.1 - 2.3e-47 160.0 0.7 6.6e-31 106.6 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KEZ41165.1 - 1.8e-33 115.1 2.8 2.9e-33 114.5 1.9 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KEZ41165.1 - 2.3e-15 56.2 0.0 1.2e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) RNase_P_Rpp14 PF01900.14 KEZ41166.1 - 1.7e-20 72.9 0.3 2.1e-20 72.6 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family GspH PF12019.3 KEZ41166.1 - 0.064 13.3 0.1 0.081 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II transport protein GspH ATP_bind_1 PF03029.12 KEZ41167.1 - 5.3e-47 160.3 0.0 6.1e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KEZ41167.1 - 0.00033 19.5 0.0 0.00042 19.1 0.0 1.1 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 KEZ41167.1 - 0.0037 18.0 0.7 0.0091 16.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 KEZ41167.1 - 0.004 16.5 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 KEZ41167.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KEZ41167.1 - 0.019 14.8 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEZ41167.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain cNMP_binding PF00027.24 KEZ41168.1 - 6.1e-40 134.9 0.0 3e-18 65.4 0.0 4.1 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KEZ41168.1 - 8.3e-18 65.0 2.7 4e-13 49.7 1.5 2.6 2 0 0 2 2 2 2 Patatin-like phospholipase Pyridoxal_deC PF00282.14 KEZ41169.1 - 7e-115 383.4 0.0 8.2e-115 383.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KEZ41169.1 - 0.005 16.0 0.1 0.022 13.9 0.1 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase AIRS PF00586.19 KEZ41169.1 - 0.022 14.9 0.1 0.083 13.1 0.0 2.0 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain EMP70 PF02990.11 KEZ41170.1 - 2.9e-168 560.5 0.0 4.2e-168 560.0 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Zip PF02535.17 KEZ41171.1 - 7.5e-61 205.8 11.3 1.5e-60 204.8 7.8 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_17 PF00332.13 KEZ41172.1 - 2.8e-06 26.6 0.0 5.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Hamartin PF04388.7 KEZ41173.1 - 6.7e-44 150.6 7.4 6.7e-44 150.6 5.1 1.7 1 1 0 1 1 1 1 Hamartin protein Sec7_N PF12783.2 KEZ41173.1 - 0.034 13.5 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF447 PF04289.7 KEZ41173.1 - 0.097 12.2 3.9 0.083 12.4 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF447) DUF4066 PF13278.1 KEZ41174.1 - 1e-18 67.1 0.5 2.8e-17 62.4 0.4 2.2 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEZ41174.1 - 6.1e-05 22.5 0.1 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DUF1626 PF07788.6 KEZ41174.1 - 0.023 14.4 0.1 9.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1626) Methyltransf_2 PF00891.13 KEZ41175.1 - 8.8e-18 64.3 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase HTH_24 PF13412.1 KEZ41175.1 - 0.0099 15.2 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Methyltransf_18 PF12847.2 KEZ41175.1 - 0.011 16.3 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HTH_IclR PF09339.5 KEZ41175.1 - 0.023 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain MTS PF05175.9 KEZ41175.1 - 0.14 11.4 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KEZ41175.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 KEZ41176.1 - 9.3e-53 179.3 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4391 PF14335.1 KEZ41177.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Pkinase PF00069.20 KEZ41179.1 - 2.3e-20 72.8 0.0 3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41179.1 - 3.5e-08 32.8 0.0 5.5e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L23 PF00276.15 KEZ41180.1 - 6.4e-13 48.4 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Mito_carr PF00153.22 KEZ41181.1 - 5.1e-63 208.8 5.8 5.2e-22 77.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ORC4_C PF14629.1 KEZ41182.1 - 5.8e-54 182.5 0.0 8e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KEZ41182.1 - 1.1e-11 45.1 0.0 8.5e-11 42.1 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain PHD PF00628.24 KEZ41182.1 - 2e-10 40.2 7.6 3.3e-10 39.5 5.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KEZ41182.1 - 9.5e-08 31.2 2.7 2e-07 30.2 1.9 1.6 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.1 KEZ41182.1 - 1.1e-06 28.7 0.0 2.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEZ41182.1 - 3.7e-06 27.1 0.0 8.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KEZ41182.1 - 0.00016 20.7 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.8 KEZ41182.1 - 0.00025 20.0 0.2 0.00052 19.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 KEZ41182.1 - 0.00046 19.8 0.1 0.0029 17.2 0.1 2.1 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KEZ41182.1 - 0.002 17.0 0.1 0.0032 16.3 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KEZ41182.1 - 0.0039 16.9 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase ATP-synt_ab PF00006.20 KEZ41182.1 - 0.0074 15.8 0.1 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain C1_1 PF00130.17 KEZ41182.1 - 0.009 15.7 0.5 0.022 14.5 0.3 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ABC_tran PF00005.22 KEZ41182.1 - 0.011 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KEZ41182.1 - 0.014 14.8 0.1 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FYVE_2 PF02318.11 KEZ41182.1 - 0.029 14.2 0.9 0.059 13.2 0.6 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Bac_DnaA PF00308.13 KEZ41182.1 - 0.047 13.3 0.0 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_14 PF13173.1 KEZ41182.1 - 0.094 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Prok-RING_1 PF14446.1 KEZ41182.1 - 0.13 11.9 1.9 0.32 10.7 1.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RGS PF00615.14 KEZ41183.1 - 5.6e-37 126.4 0.6 1.6e-36 125.0 0.0 2.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 KEZ41183.1 - 2.5e-24 84.8 0.0 1.9e-18 65.9 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73 PF05179.9 KEZ41184.1 - 1.9e-45 155.3 0.0 2.8e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Methyltransf_28 PF02636.12 KEZ41184.1 - 0.056 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PfkB PF00294.19 KEZ41185.1 - 5.2e-56 189.9 0.1 6.2e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KEZ41185.1 - 0.0024 17.1 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Bystin PF05291.6 KEZ41186.1 - 2.8e-114 381.1 0.0 3.8e-114 380.7 0.0 1.1 1 0 0 1 1 1 1 Bystin Mak16 PF04874.9 KEZ41186.1 - 1.1 9.3 7.5 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 Mak16 protein C-terminal region DUF383 PF04063.9 KEZ41187.1 - 3.4e-69 232.2 0.5 1.3e-68 230.3 0.1 2.2 4 0 0 4 4 4 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KEZ41187.1 - 1.4e-20 72.5 0.5 3.8e-20 71.1 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF427 PF04248.7 KEZ41188.1 - 1.6e-30 104.5 0.3 1.8e-30 104.4 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DUF221 PF02714.10 KEZ41189.1 - 1.9e-97 326.0 22.7 1.9e-97 326.0 15.7 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEZ41189.1 - 4.6e-41 139.9 0.3 4.6e-41 139.9 0.2 3.3 2 1 2 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KEZ41189.1 - 2.3e-17 62.6 0.0 7.3e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KEZ41189.1 - 2.1e-10 40.9 15.4 4.4e-05 23.9 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) Rifin_STEVOR PF02009.11 KEZ41189.1 - 0.039 13.6 2.0 0.089 12.4 1.4 1.6 1 0 0 1 1 1 0 Rifin/stevor family Glycophorin_A PF01102.13 KEZ41189.1 - 1.8 8.3 8.6 0.047 13.4 0.7 2.3 2 0 0 2 2 2 0 Glycophorin A DUF3377 PF11857.3 KEZ41189.1 - 7.2 6.3 9.9 5.7 6.6 1.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) FAD_binding_3 PF01494.14 KEZ41190.1 - 9.2e-16 57.8 0.1 7.2e-15 54.8 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ41190.1 - 9.1e-06 25.6 0.3 1.9e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ41190.1 - 0.0004 20.4 0.0 0.00074 19.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ41190.1 - 0.00065 18.7 0.6 0.0016 17.4 0.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ41190.1 - 0.0036 17.2 0.4 0.0076 16.1 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ41190.1 - 0.0086 14.9 0.8 0.015 14.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEZ41190.1 - 0.035 14.5 0.1 0.1 13.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ41190.1 - 0.053 12.5 0.1 0.096 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 KEZ41190.1 - 0.069 12.5 0.4 0.14 11.5 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KEZ41190.1 - 0.07 12.9 0.2 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 ThiF family 120_Rick_ant PF12574.3 KEZ41190.1 - 0.084 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen 3HCDH_N PF02737.13 KEZ41190.1 - 0.59 9.7 2.7 0.47 10.0 0.5 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 KEZ41192.1 - 3.8e-40 137.7 0.0 3.1e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.21 KEZ41194.1 - 7.6e-07 28.6 1.0 1.3e-06 27.9 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1014 PF06244.7 KEZ41195.1 - 8.7e-22 77.6 5.0 1.6e-21 76.7 3.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) MFS_1 PF07690.11 KEZ41196.1 - 1e-38 133.0 17.6 2.5e-37 128.4 9.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ41196.1 - 2.2e-11 43.0 3.4 2.2e-11 43.0 2.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KEZ41196.1 - 0.00094 17.6 21.0 0.0042 15.5 2.2 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein ERK-JNK_inhib PF15002.1 KEZ41196.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Fungal_trans PF04082.13 KEZ41197.1 - 8e-34 116.6 0.0 1.2e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41197.1 - 0.11 12.4 0.5 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FxsA PF04186.8 KEZ41197.1 - 0.23 11.0 0.7 0.45 10.1 0.5 1.4 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein DUF605 PF04652.11 KEZ41197.1 - 1.2 8.4 16.1 0.33 10.2 1.6 2.5 2 0 0 2 2 2 0 Vta1 like WD40 PF00400.27 KEZ41198.1 - 2.8e-21 74.5 3.9 5.5e-05 22.8 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat FYVE PF01363.16 KEZ41199.1 - 4.8e-07 29.5 26.6 0.0046 16.8 2.8 3.3 3 0 0 3 3 3 3 FYVE zinc finger FYVE_2 PF02318.11 KEZ41199.1 - 0.0047 16.8 26.0 0.24 11.3 3.1 3.8 4 0 0 4 4 4 3 FYVE-type zinc finger Clr2 PF10383.4 KEZ41200.1 - 0.0001 22.2 0.5 0.0032 17.4 0.3 2.8 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 DUF4381 PF14316.1 KEZ41201.1 - 0.086 12.9 0.5 0.41 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2752 PF10825.3 KEZ41201.1 - 0.36 10.9 2.7 0.59 10.1 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) SPRY PF00622.23 KEZ41202.1 - 5.3e-08 32.9 0.0 1.5e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 SPRY domain Mito_carr PF00153.22 KEZ41203.1 - 6.5e-61 202.0 0.1 4.6e-20 71.1 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.18 KEZ41203.1 - 8e-05 22.2 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase S24-like EIF_2_alpha PF07541.7 KEZ41204.1 - 4.2e-39 132.7 0.0 9.8e-39 131.6 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KEZ41204.1 - 3.9e-13 49.2 0.7 9.6e-13 48.0 0.5 1.7 1 0 0 1 1 1 1 S1 RNA binding domain F-box PF00646.28 KEZ41205.1 - 1e-08 34.6 0.0 1.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEZ41205.1 - 1.2e-08 34.5 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like Met_gamma_lyase PF06838.6 KEZ41205.1 - 0.24 9.6 0.0 0.38 9.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Asp PF00026.18 KEZ41206.1 - 3.8e-07 29.6 0.0 1.4e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.10 KEZ41206.1 - 2.1e-06 27.1 2.3 4.4e-06 26.1 1.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.13 KEZ41206.1 - 0.0015 18.2 0.0 0.0048 16.6 0.0 1.8 1 0 0 1 1 1 1 Glycophorin A Herpes_gE PF02480.11 KEZ41206.1 - 0.0089 14.3 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E AJAP1_PANP_C PF15298.1 KEZ41206.1 - 0.0097 15.8 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Mid2 PF04478.7 KEZ41206.1 - 0.015 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Shisa PF13908.1 KEZ41206.1 - 0.045 13.9 1.3 0.094 12.8 0.0 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Syndecan PF01034.15 KEZ41206.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain LRR19-TM PF15176.1 KEZ41206.1 - 0.096 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EphA2_TM PF14575.1 KEZ41206.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 KEZ41206.1 - 0.16 11.3 1.2 0.3 10.4 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lamp PF01299.12 KEZ41206.1 - 2.9 6.9 4.4 0.54 9.3 0.0 2.0 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) FAD_binding_1 PF00667.15 KEZ41207.1 - 1.8e-32 112.5 0.0 2.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEZ41207.1 - 3.4e-28 98.4 0.0 5.8e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEZ41207.1 - 1.9e-07 31.6 0.0 3e-06 27.7 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KEZ41207.1 - 0.0035 17.3 0.0 0.088 12.7 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_3 PF12641.2 KEZ41207.1 - 0.09 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain RRM_1 PF00076.17 KEZ41208.1 - 3.1e-31 106.8 0.1 4e-14 51.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41208.1 - 1.2e-23 82.8 0.0 4.2e-11 42.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41208.1 - 5.7e-09 35.7 0.0 0.001 18.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 KEZ41208.1 - 0.053 13.1 0.2 6.1 6.5 0.0 2.6 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.3 KEZ41208.1 - 0.076 12.7 0.5 6.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 API5 PF05918.6 KEZ41208.1 - 0.12 10.8 1.5 0.15 10.4 1.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ArfGap PF01412.13 KEZ41209.1 - 1.1e-31 108.9 0.1 2.4e-31 107.9 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CPSase_sm_chain PF00988.17 KEZ41210.1 - 2.8e-47 159.4 0.0 4.3e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KEZ41210.1 - 4.2e-46 156.8 0.0 5.8e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEZ41210.1 - 7.5e-07 28.8 0.1 6.7e-05 22.4 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ETF PF01012.16 KEZ41211.1 - 8.3e-36 123.1 0.6 1.1e-35 122.7 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Parathyroid PF01279.12 KEZ41212.1 - 0.093 13.3 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Parathyroid hormone family Clr5 PF14420.1 KEZ41213.1 - 1.4e-13 50.5 3.0 3.6e-13 49.1 2.1 1.8 1 0 0 1 1 1 1 Clr5 domain Baculo_gp41 PF04700.7 KEZ41214.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region SH3_8 PF13457.1 KEZ41214.1 - 0.33 11.1 2.2 9.7 6.4 0.3 2.4 1 1 1 2 2 2 0 SH3-like domain Kinesin PF00225.18 KEZ41216.1 - 7.1e-110 366.8 0.6 2e-109 365.3 0.4 1.7 1 0 0 1 1 1 1 Kinesin motor domain AAA_10 PF12846.2 KEZ41216.1 - 0.065 12.6 0.0 0.065 12.6 0.0 2.8 2 1 0 2 2 2 0 AAA-like domain CENP-F_leu_zip PF10473.4 KEZ41216.1 - 0.2 11.5 73.1 1.6 8.6 17.4 5.1 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 KEZ41216.1 - 0.36 10.2 62.1 0.23 10.8 9.6 4.3 4 1 1 5 5 5 0 Intermediate filament protein UQ_con PF00179.21 KEZ41217.1 - 4.4e-52 175.2 0.1 4.9e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ41217.1 - 4.5e-07 29.6 0.0 5.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEZ41217.1 - 0.018 14.9 0.3 0.038 13.8 0.2 1.7 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 KEZ41218.1 - 9.1e-95 316.6 0.7 1.4e-94 316.0 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEZ41218.1 - 1.9e-37 127.4 0.7 5.6e-37 125.8 0.5 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KEZ41218.1 - 0.00021 20.8 0.4 0.00052 19.5 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PCI PF01399.22 KEZ41218.1 - 0.045 14.0 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 PCI domain ACP_syn_III PF08545.5 KEZ41218.1 - 3.4 7.3 5.9 21 4.8 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SUN PF03856.8 KEZ41219.1 - 4.4e-71 239.0 8.8 5.7e-71 238.7 6.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Cupin_1 PF00190.17 KEZ41220.1 - 1.4e-09 37.5 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KEZ41220.1 - 0.032 13.7 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain GTP_EFTU PF00009.22 KEZ41221.1 - 9.1e-50 168.7 0.0 1.5e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KEZ41221.1 - 2.1e-22 78.7 0.0 4.8e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KEZ41221.1 - 4.4e-16 58.5 0.1 4.2e-14 52.1 0.1 3.2 2 1 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.13 KEZ41221.1 - 0.0025 17.3 0.0 0.0074 15.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV COPI_assoc PF08507.5 KEZ41222.1 - 1.2e-37 128.6 3.8 1.3e-37 128.5 2.6 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2231 PF09990.4 KEZ41222.1 - 0.02 15.2 0.7 0.03 14.6 0.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) Sec62 PF03839.11 KEZ41222.1 - 0.68 9.2 3.8 0.81 9.0 2.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 GATA PF00320.22 KEZ41223.1 - 4.8e-31 105.7 17.5 2.1e-16 58.9 2.0 2.7 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KEZ41223.1 - 0.00052 19.2 4.1 0.043 13.1 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KEZ41223.1 - 0.015 14.4 3.9 0.45 9.8 0.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain RRN7 PF11781.3 KEZ41223.1 - 0.017 14.5 7.0 0.65 9.5 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 KEZ41223.1 - 0.032 14.1 2.6 7.5 6.6 0.1 3.0 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KEZ41223.1 - 0.039 13.6 5.9 0.11 12.1 0.9 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.7 KEZ41223.1 - 0.93 9.3 3.4 3.5 7.4 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L32p PF01783.18 KEZ41223.1 - 2.4 8.3 10.6 10 6.3 1.7 4.1 2 2 0 2 2 2 0 Ribosomal L32p protein family eIF-5_eIF-2B PF01873.12 KEZ41223.1 - 2.5 7.7 6.2 9.2 5.9 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn_Tnp_IS1595 PF12760.2 KEZ41223.1 - 3.7 7.4 6.9 2 8.2 0.8 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain LCM PF04072.9 KEZ41224.1 - 2.4e-21 76.0 0.0 1.4e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase RINT1_TIP1 PF04437.8 KEZ41224.1 - 0.13 10.7 0.1 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family TFIID-18kDa PF02269.11 KEZ41225.1 - 1.3e-27 95.4 1.6 5.3e-27 93.4 0.0 2.6 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit DUF2422 PF10337.4 KEZ41226.1 - 2e-07 30.1 0.9 2e-07 30.1 0.6 4.1 3 1 1 5 5 5 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KEZ41226.1 - 1.1e-06 28.5 15.3 1.1e-06 28.5 10.6 3.2 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KEZ41226.1 - 0.57 8.7 20.8 0.18 10.4 0.0 3.3 2 2 2 4 4 4 0 Aluminium activated malate transporter Clat_adaptor_s PF01217.15 KEZ41227.1 - 3.1e-43 146.8 1.4 3.4e-43 146.7 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.2 KEZ41228.1 - 3.7e-55 183.7 0.0 5.1e-35 119.2 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 KEZ41228.1 - 7.9e-16 57.7 0.2 1.2e-05 25.0 0.0 4.4 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 KEZ41228.1 - 9.1e-16 57.9 0.5 7.9e-14 51.6 0.0 3.3 3 1 1 4 4 4 1 Trypsin-like peptidase domain PDZ PF00595.19 KEZ41228.1 - 1.1e-09 38.3 0.0 8.1e-05 22.7 0.0 3.9 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 KEZ41228.1 - 0.0025 17.5 0.3 0.33 10.7 0.1 3.7 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.4 KEZ41228.1 - 0.01 14.2 0.0 0.02 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.11 KEZ41228.1 - 0.074 12.3 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 KEZ41228.1 - 0.077 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease MCM2_N PF12619.3 KEZ41229.1 - 0.027 14.4 1.9 0.037 14.0 1.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 DnaJ PF00226.26 KEZ41230.1 - 1.8e-18 65.9 0.2 3.5e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF964 PF06133.6 KEZ41230.1 - 0.31 11.0 5.2 6.3 6.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF964) CUE PF02845.11 KEZ41231.1 - 7.2e-12 44.5 0.0 1.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1049 PF06305.6 KEZ41231.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1510 PF07423.6 KEZ41231.1 - 0.23 10.7 3.7 3.4 6.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) NOT2_3_5 PF04153.13 KEZ41232.1 - 1e-32 112.7 0.6 1.5e-32 112.2 0.4 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.14 KEZ41233.1 - 6.6e-46 155.9 0.3 9.2e-46 155.5 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KEZ41233.1 - 6.7e-05 22.5 0.0 0.00039 20.0 0.0 2.1 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KEZ41233.1 - 0.00012 21.5 0.0 0.061 12.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KEZ41233.1 - 0.00065 20.0 0.1 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 KEZ41233.1 - 0.00083 18.9 0.6 0.0065 16.0 0.4 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KEZ41233.1 - 0.0014 17.5 0.8 1.5 7.4 0.0 2.9 3 0 0 3 3 3 2 ArgK protein AAA_22 PF13401.1 KEZ41233.1 - 0.0022 18.1 0.5 0.16 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 KEZ41233.1 - 0.0035 16.4 0.2 0.61 9.0 0.0 2.4 2 0 0 2 2 2 1 Septin AAA_30 PF13604.1 KEZ41233.1 - 0.0058 16.2 0.3 0.41 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KEZ41233.1 - 0.0099 16.3 0.2 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 KEZ41233.1 - 0.022 14.4 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 KEZ41233.1 - 0.024 14.5 0.5 0.086 12.8 0.3 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KEZ41233.1 - 0.027 14.7 0.4 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEZ41233.1 - 0.03 13.8 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KEZ41233.1 - 0.036 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 KEZ41233.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 KEZ41233.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 KEZ41233.1 - 0.077 11.8 0.7 0.27 10.1 0.0 2.1 2 1 1 3 3 3 0 Type II/IV secretion system protein ThuA PF06283.6 KEZ41233.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation Zeta_toxin PF06414.7 KEZ41233.1 - 0.097 11.7 0.1 0.46 9.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 KEZ41233.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 KEZ41233.1 - 0.1 12.2 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KEZ41233.1 - 0.11 12.4 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mob1_phocein PF03637.12 KEZ41234.1 - 2.4e-26 92.4 0.8 3.9e-26 91.7 0.5 1.2 1 0 0 1 1 1 1 Mob1/phocein family FbpA PF05833.6 KEZ41234.1 - 0.026 13.0 0.0 0.046 12.2 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Fungal_trans_2 PF11951.3 KEZ41235.1 - 8.1e-12 44.4 0.0 2e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41235.1 - 4.9e-07 29.5 10.9 9.6e-07 28.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoD PF09423.5 KEZ41235.1 - 0.14 10.6 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase DUF605 PF04652.11 KEZ41235.1 - 4.1 6.6 13.8 6.3 6.0 9.5 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KEZ41236.1 - 0.00027 20.1 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KEZ41236.1 - 0.16 11.3 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family MOSC_N PF03476.11 KEZ41237.1 - 7.8e-15 54.6 0.0 9.2e-14 51.1 0.0 2.2 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KEZ41237.1 - 3.1e-14 52.5 0.0 5.2e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain SMC_N PF02463.14 KEZ41238.1 - 1e-66 224.3 14.7 1.3e-65 220.7 10.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEZ41238.1 - 1.9e-22 79.4 0.3 1.9e-22 79.4 0.2 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEZ41238.1 - 2.7e-10 40.7 13.4 6.1e-06 26.4 0.5 3.5 4 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KEZ41238.1 - 8.6e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Pox_A21 PF05323.7 KEZ41238.1 - 0.058 13.7 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 Poxvirus A21 Protein Reo_sigmaC PF04582.7 KEZ41238.1 - 0.64 9.1 37.6 0.31 10.1 1.4 6.1 3 2 5 8 8 8 0 Reovirus sigma C capsid protein INCENP_ARK-bind PF03941.10 KEZ41239.1 - 1.1e-21 76.3 0.9 1.1e-21 76.3 0.6 2.8 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region DEAD PF00270.24 KEZ41241.1 - 3.9e-38 130.5 0.1 6.5e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ41241.1 - 1.1e-21 76.4 0.4 2.6e-21 75.2 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ41241.1 - 0.054 13.3 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.27 KEZ41242.1 - 2.2e-08 33.6 1.2 0.00017 21.3 0.3 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF3639 PF12341.3 KEZ41242.1 - 0.34 10.9 1.6 0.71 9.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3639) 2OG-FeII_Oxy_2 PF13532.1 KEZ41243.1 - 2e-34 119.1 0.0 2.7e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KEZ41243.1 - 3.8e-08 33.1 7.4 6.7e-08 32.3 5.1 1.4 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 KEZ41243.1 - 0.00051 20.2 0.0 0.00099 19.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DinI PF06183.8 KEZ41243.1 - 0.074 13.0 0.1 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 DinI-like family Toxin_65 PF15543.1 KEZ41243.1 - 0.074 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 65 GFA PF04828.9 KEZ41244.1 - 6.6e-15 54.8 2.2 1.4e-07 31.3 0.0 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme DUF1936 PF09151.5 KEZ41244.1 - 0.045 13.2 2.0 1.6 8.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) RNA_POL_M_15KD PF02150.11 KEZ41244.1 - 0.046 13.4 2.2 5.7 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit NOB1_Zn_bind PF08772.6 KEZ41244.1 - 0.057 13.2 5.6 1.5 8.6 0.1 3.0 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Lar_restr_allev PF14354.1 KEZ41244.1 - 0.75 10.1 12.4 18 5.6 1.3 4.3 2 2 1 3 3 3 0 Restriction alleviation protein Lar A2L_zn_ribbon PF08792.5 KEZ41244.1 - 0.8 9.2 0.0 0.8 9.2 0.0 4.5 5 0 0 5 5 5 0 A2L zinc ribbon domain zf-CSL PF05207.8 KEZ41244.1 - 2.6 7.6 13.6 0.51 9.8 0.4 3.3 4 0 0 4 4 4 0 CSL zinc finger Aldo_ket_red PF00248.16 KEZ41246.1 - 3.2e-47 160.7 0.0 3.5e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.6 KEZ41246.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like ACPS PF01648.15 KEZ41247.1 - 1.2e-11 44.4 0.0 1.6e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF1774 PF08611.5 KEZ41248.1 - 1.1e-28 99.1 0.9 1.1e-28 99.1 0.7 2.3 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Clr5 PF14420.1 KEZ41249.1 - 1.4e-05 24.8 0.1 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain DHC_N1 PF08385.7 KEZ41250.1 - 3.1e-189 630.1 1.2 3.1e-189 630.1 0.8 5.0 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KEZ41250.1 - 7.3e-133 443.0 3.3 7.3e-133 443.0 2.3 5.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KEZ41250.1 - 6.4e-106 355.0 0.0 1.3e-105 353.9 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KEZ41250.1 - 2.2e-76 256.3 0.0 5.4e-76 255.1 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 KEZ41250.1 - 4.2e-44 150.7 8.8 8.2e-44 149.7 6.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 KEZ41250.1 - 9.6e-43 145.6 0.2 2.6e-42 144.2 0.1 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KEZ41250.1 - 5.1e-42 143.6 0.1 8.4e-41 139.7 0.1 2.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 KEZ41250.1 - 2.2e-32 111.7 0.1 1.2e-10 41.2 0.0 6.6 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KEZ41250.1 - 3.9e-20 72.0 0.0 3e-19 69.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KEZ41250.1 - 9.2e-15 54.9 0.0 0.012 15.7 0.0 6.7 6 0 0 6 6 5 3 AAA domain AAA PF00004.24 KEZ41250.1 - 3.4e-13 49.9 0.0 0.0013 18.9 0.0 4.2 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ41250.1 - 3.5e-10 40.7 0.1 0.023 15.5 0.0 5.8 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 KEZ41250.1 - 1.4e-09 37.9 0.1 0.33 10.8 0.0 5.5 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.1 KEZ41250.1 - 5.5e-09 36.4 1.3 0.032 14.5 0.0 6.0 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.1 KEZ41250.1 - 1.6e-06 28.2 12.1 0.19 11.6 0.2 8.6 6 1 2 8 8 8 1 AAA ATPase domain T2SE PF00437.15 KEZ41250.1 - 5.2e-06 25.5 0.0 0.039 12.8 0.0 3.5 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 KEZ41250.1 - 7.8e-06 25.3 0.1 1.1 8.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_14 PF13173.1 KEZ41250.1 - 1.5e-05 24.8 0.0 0.28 11.0 0.0 4.7 5 0 0 5 5 3 1 AAA domain AAA_19 PF13245.1 KEZ41250.1 - 9.5e-05 22.0 0.1 0.89 9.3 0.0 4.0 4 0 0 4 4 3 1 Part of AAA domain Mg_chelatase PF01078.16 KEZ41250.1 - 0.00034 19.8 0.5 0.5 9.4 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KEZ41250.1 - 0.00075 19.8 0.0 5.7 7.2 0.0 4.7 3 0 0 3 3 3 0 ABC transporter DUF258 PF03193.11 KEZ41250.1 - 0.011 14.8 0.0 10 5.2 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KEZ41250.1 - 0.041 13.5 0.2 5.8 6.6 0.0 3.6 3 0 0 3 3 2 0 NTPase RNA_helicase PF00910.17 KEZ41250.1 - 0.051 13.7 0.1 2.1e+02 2.1 0.0 4.5 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 KEZ41250.1 - 0.097 12.3 0.1 11 5.7 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KEZ41250.1 - 0.24 10.8 6.3 0.39 10.0 0.0 3.8 5 0 0 5 5 4 0 AAA domain DUF1664 PF07889.7 KEZ41250.1 - 4.1 7.2 14.0 3.3 7.5 0.3 5.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) FAR1 PF03101.10 KEZ41251.1 - 3.5e-05 24.2 0.0 0.0001 22.7 0.0 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain Phosphodiest PF01663.17 KEZ41251.1 - 0.017 14.4 0.8 0.047 13.0 0.1 2.0 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4200 PF13863.1 KEZ41251.1 - 0.035 14.0 9.3 0.068 13.1 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NOA36 PF06524.7 KEZ41252.1 - 0.0033 16.7 1.2 0.005 16.1 0.8 1.2 1 0 0 1 1 1 1 NOA36 protein zf-C2H2_4 PF13894.1 KEZ41252.1 - 0.11 12.8 0.3 0.11 12.8 0.2 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger Acetyltransf_1 PF00583.19 KEZ41253.1 - 0.0027 17.7 0.1 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ41253.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Histone PF00125.19 KEZ41254.1 - 1.5e-06 28.2 0.6 2e-06 27.7 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KEZ41254.1 - 0.0028 17.5 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Svf1 PF08622.5 KEZ41255.1 - 1.1e-124 415.7 0.0 1.3e-124 415.4 0.0 1.1 1 0 0 1 1 1 1 Svf1-like GATA PF00320.22 KEZ41256.1 - 9.1e-14 50.5 2.4 1.6e-13 49.7 1.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Macoilin PF09726.4 KEZ41256.1 - 0.0048 15.2 2.6 0.0059 14.9 1.8 1.1 1 0 0 1 1 1 1 Transmembrane protein KxDL PF10241.4 KEZ41256.1 - 0.0059 16.4 3.1 0.011 15.6 2.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein GAS PF13851.1 KEZ41256.1 - 0.0064 15.6 4.5 0.0094 15.1 3.1 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.1 KEZ41256.1 - 0.024 13.8 9.8 0.033 13.3 6.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Atg14 PF10186.4 KEZ41256.1 - 0.029 13.3 7.7 0.047 12.6 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 KEZ41256.1 - 0.052 12.7 2.3 0.074 12.2 1.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein APG6 PF04111.7 KEZ41256.1 - 0.079 11.9 6.7 0.11 11.4 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ArfGap PF01412.13 KEZ41256.1 - 0.099 12.4 0.6 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.7 KEZ41256.1 - 0.12 12.7 5.3 0.54 10.5 0.6 2.4 1 1 1 2 2 2 0 Striatin family zf-RING_3 PF14369.1 KEZ41256.1 - 0.18 11.8 0.6 0.38 10.8 0.4 1.5 1 0 0 1 1 1 0 zinc-finger AAA_13 PF13166.1 KEZ41256.1 - 0.22 9.9 3.1 0.29 9.5 2.2 1.1 1 0 0 1 1 1 0 AAA domain DUF4164 PF13747.1 KEZ41256.1 - 0.42 10.7 12.0 0.86 9.7 8.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3138 PF11336.3 KEZ41256.1 - 1.7 6.7 7.6 0.056 11.6 1.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) PV-1 PF06637.6 KEZ41256.1 - 3.8 5.9 8.9 0.92 8.0 3.0 1.8 2 0 0 2 2 2 0 PV-1 protein (PLVAP) ADIP PF11559.3 KEZ41256.1 - 3.8 7.3 12.4 7.1 6.5 7.7 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mit_KHE1 PF10173.4 KEZ41257.1 - 4.1e-61 206.0 1.1 4.7e-61 205.9 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related SapB_1 PF05184.10 KEZ41257.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 Cullin PF00888.17 KEZ41259.1 - 5.2e-205 682.4 10.5 7.1e-205 681.9 7.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEZ41259.1 - 9.7e-26 89.3 5.6 9.7e-26 89.3 3.9 3.9 5 0 0 5 5 5 1 Cullin protein neddylation domain Rrf2 PF02082.15 KEZ41259.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Avl9 PF09794.4 KEZ41260.1 - 2.3e-146 487.1 0.0 2.9e-146 486.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 KEZ41260.1 - 2.2e-08 33.7 0.1 2.3e-07 30.3 0.1 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KEZ41260.1 - 9.9e-08 31.6 0.1 0.00022 20.8 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis Pkinase PF00069.20 KEZ41261.1 - 5.8e-72 241.9 0.0 7.2e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41261.1 - 5.7e-32 110.7 0.0 7.1e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEZ41261.1 - 1e-05 24.6 0.0 3.8e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEZ41261.1 - 0.0004 20.2 0.1 0.0011 18.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEZ41261.1 - 0.0005 19.1 0.0 0.026 13.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 KEZ41261.1 - 0.02 14.2 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Phosphorylase PF00343.15 KEZ41262.1 - 0 1067.9 0.0 0 1067.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.15 KEZ41263.1 - 4.7e-102 341.5 2.5 2.6e-65 220.6 0.2 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KEZ41263.1 - 7.4e-13 48.1 0.4 1.9e-07 30.5 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KEZ41263.1 - 0.036 14.5 0.2 1.1 9.8 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 KEZ41263.1 - 0.042 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KEZ41263.1 - 0.059 12.5 0.0 2.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Penicil_amidase PF01804.13 KEZ41263.1 - 0.086 11.8 0.0 3.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Penicillin amidase DUF2985 PF11204.3 KEZ41263.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) SH3_9 PF14604.1 KEZ41264.1 - 2.7e-12 46.0 0.6 1.3e-10 40.6 0.3 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KEZ41264.1 - 3.5e-05 23.1 1.0 9.9e-05 21.7 0.7 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ41264.1 - 0.04 13.3 4.8 0.082 12.3 3.3 1.6 1 0 0 1 1 1 0 SH3 domain Anoctamin PF04547.7 KEZ41265.1 - 3.3e-114 382.0 4.2 3.9e-114 381.7 2.9 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF4158 PF13700.1 KEZ41265.1 - 0.11 11.9 0.1 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) RRM_1 PF00076.17 KEZ41266.1 - 7.6e-22 76.7 0.0 1.2e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41266.1 - 3.4e-15 55.7 0.0 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41266.1 - 0.00031 20.5 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 KEZ41267.1 - 2.9e-58 196.8 0.0 4.2e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEZ41267.1 - 4.1e-34 117.6 0.3 1e-33 116.3 0.2 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEZ41267.1 - 2e-21 76.6 0.0 1.1e-20 74.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KEZ41267.1 - 0.008 16.1 0.1 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain MOR2-PAG1_N PF14222.1 KEZ41268.1 - 2.9e-217 722.7 0.0 5.3e-217 721.8 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KEZ41268.1 - 3.8e-92 308.7 0.6 3.8e-92 308.7 0.4 2.4 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KEZ41268.1 - 1.2e-40 139.0 6.6 9e-16 56.7 0.0 3.8 1 1 1 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.1 KEZ41268.1 - 0.00038 20.6 0.0 4 7.7 0.0 5.1 5 0 0 5 5 5 1 HEAT repeats CRM1_C PF08767.6 KEZ41268.1 - 0.026 13.4 0.1 0.096 11.5 0.0 1.9 1 0 0 1 1 1 0 CRM1 C terminal HEAT PF02985.17 KEZ41268.1 - 0.067 13.2 5.5 33 4.9 0.0 5.9 7 0 0 7 7 7 0 HEAT repeat Cnd1 PF12717.2 KEZ41268.1 - 0.17 11.7 2.5 1.8 8.3 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DIM1 PF02966.11 KEZ41269.1 - 3.4e-67 224.0 0.0 3.9e-67 223.8 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 KEZ41269.1 - 0.03 14.4 0.2 0.07 13.2 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 KEZ41269.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Sec62 PF03839.11 KEZ41270.1 - 3.4e-55 186.9 1.4 3.4e-55 186.9 0.9 1.6 2 0 0 2 2 2 1 Translocation protein Sec62 DSBA PF01323.15 KEZ41270.1 - 0.016 14.7 0.7 0.042 13.4 0.5 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain APC_CDC26 PF10471.4 KEZ41270.1 - 0.51 11.1 6.5 0.15 12.8 0.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PLDc_2 PF13091.1 KEZ41271.1 - 5.7e-13 48.7 0.0 7.7e-06 25.6 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KEZ41271.1 - 5e-10 38.8 0.7 0.00089 18.9 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Pox_A12 PF04651.8 KEZ41271.1 - 0.1 12.7 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Thioredoxin PF00085.15 KEZ41272.1 - 5.6e-40 135.2 0.1 1.1e-24 86.1 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KEZ41272.1 - 3.7e-15 56.2 0.0 8.5e-05 22.4 0.0 4.0 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEZ41272.1 - 6.8e-08 32.5 1.0 0.00078 19.5 0.0 5.0 4 1 0 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KEZ41272.1 - 7e-07 29.4 10.3 0.00017 21.7 0.1 4.7 5 1 0 5 5 5 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KEZ41272.1 - 0.00048 20.0 0.0 0.0024 17.8 0.0 2.2 1 0 0 1 1 1 1 Thioredoxin-like Calsequestrin PF01216.12 KEZ41272.1 - 0.0011 17.8 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 Calsequestrin HyaE PF07449.6 KEZ41272.1 - 0.0072 16.2 0.0 20 5.1 0.0 3.7 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 KEZ41272.1 - 0.017 14.8 0.1 0.57 10.0 0.0 3.5 4 0 0 4 4 4 0 Thioredoxin domain Tyr-DNA_phospho PF06087.7 KEZ41273.1 - 7e-130 433.6 0.0 8.2e-130 433.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KEZ41273.1 - 5.7e-05 22.8 0.2 0.013 15.1 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KEZ41273.1 - 0.13 12.1 0.2 3 7.7 0.2 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif ACBP PF00887.14 KEZ41274.1 - 8e-26 89.5 0.8 9.1e-26 89.3 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PrkA PF06798.7 KEZ41274.1 - 0.05 12.8 0.1 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain Pyr_redox_2 PF07992.9 KEZ41275.1 - 9.5e-21 74.5 0.2 1.6e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ41275.1 - 4.7e-09 36.5 0.1 1.5e-07 31.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ41275.1 - 3.4e-06 27.2 0.2 0.0058 16.7 0.1 3.0 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ41275.1 - 5.5e-05 22.2 2.6 0.25 10.2 0.2 3.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ41275.1 - 7.9e-05 22.4 0.2 1.3 8.8 0.0 3.6 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KEZ41275.1 - 0.023 13.6 0.0 1.9 7.3 0.0 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.1 KEZ41275.1 - 0.067 12.1 0.7 1.8 7.3 0.2 3.0 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF3786 PF12654.2 KEZ41275.1 - 0.095 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Thi4 PF01946.12 KEZ41275.1 - 0.19 10.7 1.9 0.6 9.1 0.2 2.5 3 1 0 3 3 3 0 Thi4 family End3 PF12761.2 KEZ41276.1 - 9e-74 247.3 4.5 1.2e-73 246.9 3.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KEZ41276.1 - 1.5e-49 166.0 0.0 4.9e-48 161.1 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KEZ41276.1 - 6.4e-07 28.2 0.2 1.4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KEZ41276.1 - 4.4e-06 26.1 0.1 8.4e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 KEZ41276.1 - 2.6e-05 24.2 0.0 0.00016 21.7 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEZ41276.1 - 0.00062 19.4 0.3 0.0028 17.3 0.2 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KEZ41276.1 - 0.0054 16.0 0.2 0.013 14.8 0.1 1.7 1 0 0 1 1 1 1 EF hand DUF641 PF04859.7 KEZ41276.1 - 0.019 14.7 0.4 0.019 14.7 0.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) LRS4 PF10422.4 KEZ41276.1 - 0.028 13.7 2.9 0.042 13.2 2.0 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 FlxA PF14282.1 KEZ41276.1 - 0.043 13.7 4.7 0.42 10.5 0.5 2.5 1 1 1 2 2 2 0 FlxA-like protein Vps52 PF04129.7 KEZ41276.1 - 0.066 11.7 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family DUF16 PF01519.11 KEZ41276.1 - 0.073 13.2 2.2 0.17 12.1 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 TBPIP PF07106.8 KEZ41276.1 - 0.073 12.6 5.4 1.8 8.0 1.4 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 KEZ41276.1 - 0.084 12.5 5.4 0.22 11.1 3.6 1.7 1 1 0 1 1 1 0 Mnd1 family Dynamitin PF04912.9 KEZ41276.1 - 0.09 11.5 4.9 0.1 11.3 2.2 1.8 2 1 0 2 2 2 0 Dynamitin DUF2408 PF10303.4 KEZ41276.1 - 0.11 12.5 5.8 0.053 13.6 2.1 1.9 2 1 0 3 3 1 0 Protein of unknown function (DUF2408) Bacillus_HBL PF05791.6 KEZ41276.1 - 0.14 11.5 2.2 0.9 8.8 0.2 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.7 KEZ41276.1 - 0.14 11.8 1.4 0.28 10.9 1.0 1.5 1 0 0 1 1 1 0 Laminin Domain II COG2 PF06148.6 KEZ41276.1 - 0.2 11.4 5.6 0.39 10.5 0.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 KEZ41276.1 - 0.25 11.2 3.5 11 5.9 0.3 3.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 KEZ41276.1 - 0.54 9.9 10.5 1 9.0 0.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 KEZ41276.1 - 0.64 10.1 3.2 1.8 8.7 0.0 2.6 2 1 2 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad3 PF08656.5 KEZ41276.1 - 0.68 9.6 4.6 1.6 8.4 0.3 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 Syntaxin PF00804.20 KEZ41276.1 - 2.7 8.1 6.8 13 6.0 4.8 2.0 1 1 0 1 1 1 0 Syntaxin IncA PF04156.9 KEZ41276.1 - 3.1 7.3 12.1 23 4.4 8.4 2.3 1 1 0 1 1 1 0 IncA protein DUF4164 PF13747.1 KEZ41276.1 - 4.2 7.5 11.3 6.5 6.9 2.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ketoacyl-synt PF00109.21 KEZ41277.1 - 2.9e-20 72.8 0.1 7.4e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 KEZ41277.1 - 6.1e-19 68.7 0.0 2.6e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 KEZ41277.1 - 2.4e-18 66.0 0.5 1.2e-17 63.7 0.0 2.3 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KEZ41277.1 - 9.3e-11 41.6 0.0 2.6e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KEZ41277.1 - 3.6e-05 23.7 0.0 0.00014 21.8 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41277.1 - 0.0033 17.0 0.0 0.016 14.9 0.0 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KEZ41278.1 - 5.1e-81 272.4 0.0 5.5e-78 262.5 0.0 3.3 4 0 0 4 4 4 2 Acyl transferase domain MaoC_dehydratas PF01575.14 KEZ41278.1 - 2.8e-38 130.0 0.0 6.1e-38 128.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 KEZ41278.1 - 1.4e-29 101.6 0.1 4.2e-29 100.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 KEZ41278.1 - 1.7e-20 73.1 0.2 8.1e-20 70.9 0.0 2.3 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase NMO PF03060.10 KEZ41278.1 - 1.5e-06 27.6 0.8 5.2e-05 22.5 0.6 2.7 1 1 0 1 1 1 1 Nitronate monooxygenase DREPP PF05558.7 KEZ41278.1 - 0.17 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Amidohydro_1 PF01979.15 KEZ41279.1 - 2e-39 136.1 0.0 3.4e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KEZ41279.1 - 6.1e-07 28.9 0.1 9.4e-05 21.7 0.0 2.9 2 0 0 2 2 2 2 Amidohydrolase family PPR_2 PF13041.1 KEZ41279.1 - 7.6e-05 22.6 0.0 4.8 7.2 0.0 4.5 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 KEZ41279.1 - 0.00045 20.2 2.7 7.3 7.1 0.0 6.3 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Amidohydro_5 PF13594.1 KEZ41279.1 - 0.0022 17.7 0.0 0.0072 16.1 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase PPR PF01535.15 KEZ41279.1 - 0.023 14.6 0.2 49 4.2 0.0 4.7 4 0 0 4 4 4 0 PPR repeat Zn_clus PF00172.13 KEZ41280.1 - 1e-05 25.3 10.3 1.8e-05 24.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ku PF02735.11 KEZ41281.1 - 1.6e-40 138.6 0.1 4.1e-40 137.3 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KEZ41281.1 - 7.8e-37 126.8 0.0 1.1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 KEZ41281.1 - 8.8e-17 61.4 0.2 2.8e-16 59.8 0.1 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 KEZ41281.1 - 3.8e-12 45.3 0.1 7e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain Toprim_3 PF13362.1 KEZ41281.1 - 0.0074 16.5 0.0 1.8 8.8 0.0 2.8 2 0 0 2 2 2 1 Toprim domain Ferrochelatase PF00762.14 KEZ41282.1 - 2.5e-93 312.5 0.0 3.8e-93 311.9 0.0 1.3 1 0 0 1 1 1 1 Ferrochelatase AAA PF00004.24 KEZ41282.1 - 1.2e-11 44.9 0.0 3.3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ41282.1 - 1.2e-06 28.7 0.0 2.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEZ41282.1 - 0.0001 21.4 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEZ41282.1 - 0.00016 21.3 0.0 0.00044 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KEZ41282.1 - 0.00059 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ41282.1 - 0.00096 19.0 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEZ41282.1 - 0.0011 17.7 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KEZ41282.1 - 0.0011 19.7 0.0 0.0031 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEZ41282.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEZ41282.1 - 0.0029 17.5 0.3 0.015 15.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 KEZ41282.1 - 0.0055 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KEZ41282.1 - 0.02 15.2 0.0 0.072 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KEZ41282.1 - 0.035 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KEZ41282.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 KEZ41282.1 - 0.079 12.3 0.6 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 KEZ41282.1 - 0.091 12.7 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Clp1 PF06807.9 KEZ41283.1 - 2.5e-23 82.8 0.0 3.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KEZ41283.1 - 3.3e-07 30.1 0.0 8.9e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KEZ41283.1 - 8.8e-06 25.6 0.1 6.9e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEZ41283.1 - 1.9e-05 24.3 0.1 8.7e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KEZ41283.1 - 0.00022 20.7 0.2 0.0006 19.3 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KEZ41283.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 KEZ41283.1 - 0.0035 16.5 0.0 0.0068 15.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.1 KEZ41283.1 - 0.0053 16.4 0.2 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain SRP54 PF00448.17 KEZ41283.1 - 0.0096 15.3 0.2 0.42 10.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KEZ41283.1 - 0.0097 15.3 0.1 0.024 14.0 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 KEZ41283.1 - 0.032 13.0 0.1 0.057 12.2 0.1 1.3 1 0 0 1 1 1 0 ArgK protein TrwB_AAD_bind PF10412.4 KEZ41283.1 - 0.039 12.5 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 KEZ41283.1 - 0.04 14.7 0.1 0.15 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEZ41283.1 - 0.045 13.7 1.0 0.13 12.2 0.1 2.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KEZ41283.1 - 0.049 13.9 0.2 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEZ41283.1 - 0.084 11.9 0.0 0.16 11.0 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.24 KEZ41283.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pmp3 PF01679.12 KEZ41284.1 - 1.7e-19 69.2 6.4 2.3e-19 68.8 4.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.5 KEZ41285.1 - 2.7e-48 164.8 0.0 5.3e-48 163.8 0.0 1.4 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF1131 PF06572.7 KEZ41285.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1131) DUF2967 PF11179.3 KEZ41285.1 - 0.18 11.2 7.5 0.26 10.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) IPK PF03770.11 KEZ41286.1 - 4.5e-52 176.5 0.0 6.5e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF3887 PF13026.1 KEZ41286.1 - 0.66 10.2 4.3 0.27 11.5 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) OB_NTP_bind PF07717.11 KEZ41287.1 - 5.5e-27 93.8 0.0 1.2e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEZ41287.1 - 1.1e-24 86.4 0.1 1.1e-24 86.4 0.1 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) Methyltransf_11 PF08241.7 KEZ41287.1 - 1.6e-13 50.9 0.0 4.2e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ41287.1 - 1.9e-13 50.4 0.0 5.3e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Helicase_C PF00271.26 KEZ41287.1 - 3.4e-12 46.0 0.0 8.3e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KEZ41287.1 - 2.4e-11 43.5 0.4 5e-11 42.5 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Methyltransf_12 PF08242.7 KEZ41287.1 - 8.6e-10 38.9 0.0 2.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41287.1 - 9.9e-10 38.1 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DEAD PF00270.24 KEZ41287.1 - 5.4e-07 29.2 0.2 1.1e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Methyltransf_18 PF12847.2 KEZ41287.1 - 9.7e-07 29.3 0.0 2.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AAA_22 PF13401.1 KEZ41287.1 - 4.6e-06 26.7 0.1 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KEZ41287.1 - 0.00012 21.1 0.0 0.00027 19.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NNMT_PNMT_TEMT PF01234.12 KEZ41287.1 - 0.00097 18.1 0.1 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family PRP38_assoc PF12871.2 KEZ41287.1 - 0.0011 19.4 28.5 0.0035 17.8 19.8 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA_14 PF13173.1 KEZ41287.1 - 0.0074 16.1 0.2 0.06 13.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ41287.1 - 0.0081 15.8 0.1 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 KEZ41287.1 - 0.0099 16.1 0.5 0.33 11.2 0.1 2.7 1 1 1 2 2 2 1 ABC transporter Methyltransf_9 PF08003.6 KEZ41287.1 - 0.016 13.9 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AAA_30 PF13604.1 KEZ41287.1 - 0.025 14.1 0.4 0.062 12.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain Methyltransf_26 PF13659.1 KEZ41287.1 - 0.037 14.0 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KEZ41287.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ResIII PF04851.10 KEZ41287.1 - 0.066 13.0 0.2 5.6 6.7 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KEZ41287.1 - 0.1 11.8 0.1 0.33 10.1 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein DUF1509 PF07420.6 KEZ41287.1 - 0.12 11.6 13.4 0.23 10.6 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Myosin_head PF00063.16 KEZ41287.1 - 0.12 10.3 0.1 0.19 9.6 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) SRP54 PF00448.17 KEZ41287.1 - 0.16 11.4 0.4 0.37 10.1 0.3 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 KEZ41287.1 - 0.16 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Ubie_methyltran PF01209.13 KEZ41287.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KEZ41288.1 - 1.6e-32 112.6 0.0 2.4e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KEZ41288.1 - 0.0049 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 KEZ41289.1 - 5.7e-18 65.6 0.2 7.3e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ41289.1 - 6.6e-15 55.1 0.0 2e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ41289.1 - 2.3e-07 30.2 0.2 0.0083 15.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 KEZ41289.1 - 3.8e-05 22.3 0.0 0.011 14.2 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KEZ41289.1 - 0.0098 15.6 0.0 0.17 11.6 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 KEZ41289.1 - 0.01 14.4 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) VHP PF02209.14 KEZ41289.1 - 0.015 14.9 0.4 0.18 11.5 0.1 2.4 2 0 0 2 2 2 0 Villin headpiece domain Hydrolase_4 PF12146.3 KEZ41289.1 - 0.046 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 KEZ41289.1 - 0.082 12.1 0.0 0.3 10.3 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family Mito_carr PF00153.22 KEZ41290.1 - 2.2e-40 136.2 10.1 2.2e-19 68.9 0.2 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Epiglycanin_TR PF05647.6 KEZ41290.1 - 0.043 13.6 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Abhydrolase_6 PF12697.2 KEZ41291.1 - 2.7e-17 63.4 0.1 3.2e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ41291.1 - 5.9e-17 61.7 0.0 1.1e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEZ41291.1 - 1.8e-09 37.4 0.0 2.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 KEZ41291.1 - 4.2e-07 29.4 0.0 3.1e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KEZ41291.1 - 4.3e-06 26.1 0.0 1e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 KEZ41291.1 - 2.3e-05 23.0 0.0 0.0064 15.0 0.0 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 KEZ41291.1 - 0.00025 20.8 0.0 0.00065 19.4 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 KEZ41291.1 - 0.00073 18.2 0.0 0.0028 16.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.8 KEZ41291.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEZ41291.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase ADH_zinc_N PF00107.21 KEZ41292.1 - 3.1e-09 36.4 0.0 5.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ41292.1 - 7.5e-05 22.4 0.4 7.5e-05 22.4 0.3 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 KEZ41293.1 - 1.8e-74 250.4 0.0 6e-74 248.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEZ41293.1 - 1.7e-48 165.5 0.0 3.7e-48 164.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEZ41293.1 - 7.3e-48 162.6 1.3 7.7e-47 159.2 0.0 3.0 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 KEZ41293.1 - 1.8e-43 148.3 1.4 2.5e-41 141.3 0.0 3.7 4 0 0 4 4 2 1 short chain dehydrogenase PS-DH PF14765.1 KEZ41293.1 - 1.7e-41 142.3 0.2 2.8e-41 141.6 0.2 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 KEZ41293.1 - 2.1e-32 112.0 0.0 1.4e-31 109.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KEZ41293.1 - 7.5e-31 106.4 0.0 1.9e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEZ41293.1 - 3e-18 66.0 0.0 8.2e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KEZ41293.1 - 1.8e-15 57.0 0.0 8.4e-14 51.5 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KEZ41293.1 - 1.8e-13 50.7 0.0 5.5e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ41293.1 - 4.2e-12 46.0 0.0 1.8e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41293.1 - 1.7e-10 41.4 0.0 8.3e-10 39.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41293.1 - 1.5e-08 34.3 0.0 3.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ41293.1 - 1.7e-08 34.7 0.0 6.4e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ41293.1 - 2.2e-07 30.2 0.0 4.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 KEZ41293.1 - 4.1e-06 26.9 0.0 9.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KEZ41293.1 - 5.8e-06 25.2 0.0 1.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family MTS PF05175.9 KEZ41293.1 - 7e-05 22.2 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ41293.1 - 0.00016 21.7 0.0 0.00092 19.2 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ41293.1 - 0.0019 17.6 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 KEZ41293.1 - 0.011 14.7 0.0 0.04 12.9 0.0 1.9 2 0 0 2 2 2 0 Thiolase, N-terminal domain Methyltransf_24 PF13578.1 KEZ41293.1 - 0.011 16.5 0.0 0.082 13.7 0.0 2.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KEZ41293.1 - 0.019 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KEZ41293.1 - 0.6 9.1 0.0 9.1 5.2 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 KEZ41293.1 - 1 8.9 0.0 2.1 7.9 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase MFS_1 PF07690.11 KEZ41294.1 - 3.5e-36 124.6 44.7 3.5e-36 124.6 31.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KEZ41295.1 - 1.4e-15 57.2 4.6 7.8e-12 44.9 0.2 3.1 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEZ41295.1 - 7.3e-05 21.8 1.4 0.0095 14.8 0.6 2.5 2 1 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.9 KEZ41295.1 - 0.00026 19.7 0.0 0.017 13.7 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 KEZ41295.1 - 0.0004 19.4 0.6 0.25 10.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ41295.1 - 0.0012 17.4 0.1 0.43 8.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 KEZ41295.1 - 0.011 14.6 0.4 0.017 14.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KEZ41295.1 - 0.065 13.0 0.1 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEZ41295.1 - 0.091 12.6 0.2 0.28 11.0 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ41295.1 - 0.096 11.7 0.6 3.5 6.5 0.3 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ41295.1 - 0.54 10.7 2.9 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Git3 PF11710.3 KEZ41296.1 - 8.3e-66 221.4 19.1 1e-65 221.1 11.0 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KEZ41296.1 - 3.2e-22 78.0 0.3 3.2e-22 78.0 0.2 3.1 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KEZ41296.1 - 5.8e-09 35.4 0.6 8.9e-09 34.8 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.10 KEZ41296.1 - 0.00023 20.3 15.0 0.0042 16.1 2.0 3.1 3 0 0 3 3 3 2 Pheromone A receptor DUF4381 PF14316.1 KEZ41296.1 - 0.48 10.5 3.0 0.39 10.8 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) GATase PF00117.23 KEZ41297.1 - 5.1e-13 48.9 0.0 6.7e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KEZ41297.1 - 0.001 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KEZ41297.1 - 0.0079 15.6 0.1 0.027 13.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 DHHA2 PF02833.9 KEZ41298.1 - 6.3e-27 94.2 0.0 1.2e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KEZ41298.1 - 1.3e-09 37.8 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 DHH family DUF3574 PF12098.3 KEZ41298.1 - 0.025 14.1 0.0 0.085 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) P-mevalo_kinase PF04275.9 KEZ41298.1 - 0.12 12.1 0.1 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphomevalonate kinase RNA_pol PF00940.14 KEZ41299.1 - 1.9e-162 540.3 0.0 2.7e-162 539.8 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KEZ41299.1 - 1.1e-72 244.9 0.5 5.3e-72 242.7 0.6 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal SNF2_N PF00176.18 KEZ41300.1 - 7.5e-65 218.6 0.0 4.4e-64 216.1 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ41300.1 - 6.4e-17 61.1 0.0 1.7e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ41300.1 - 8.1e-08 32.2 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Phosphodiest PF01663.17 KEZ41301.1 - 8.9e-88 295.0 0.3 1.5e-87 294.3 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.7 KEZ41301.1 - 0.00084 19.0 0.0 0.0026 17.4 0.0 1.8 2 0 0 2 2 2 1 PglZ domain Sulfatase PF00884.18 KEZ41301.1 - 0.0037 16.5 0.1 0.23 10.5 0.1 2.3 1 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 KEZ41301.1 - 0.016 14.5 0.2 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF912 PF06024.7 KEZ41301.1 - 0.046 13.7 0.2 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 KEZ41301.1 - 0.25 11.6 18.4 0.06 13.6 2.8 3.9 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 KEZ41303.1 - 9.8e-19 67.4 0.0 9.8e-09 35.4 0.0 4.4 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ41303.1 - 2.6e-15 56.4 0.3 0.038 14.5 0.0 6.1 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ41303.1 - 1.9e-14 53.3 3.9 6.2e-05 23.1 0.0 6.2 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ41303.1 - 1.6e-09 37.0 1.5 0.53 10.6 0.0 6.8 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.25 KEZ41303.1 - 2.9e-09 36.2 2.9 0.026 14.3 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat AAA_22 PF13401.1 KEZ41303.1 - 0.01 15.9 0.5 0.026 14.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1843 PF08898.5 KEZ41303.1 - 0.16 12.0 0.2 8 6.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) SNF PF00209.13 KEZ41304.1 - 1.6e-81 274.3 33.6 2.6e-80 270.3 23.3 2.1 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family adh_short_C2 PF13561.1 KEZ41305.1 - 3.5e-26 92.4 0.0 5.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ41305.1 - 5.5e-24 84.9 0.7 8.4e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41305.1 - 5.5e-12 45.7 0.2 1.1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ41305.1 - 0.00071 19.0 0.1 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CDC27 PF09507.5 KEZ41305.1 - 0.8 8.8 44.9 1.5 8.0 31.1 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 KEZ41305.1 - 3.5 5.9 45.3 7.3 4.9 31.4 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NAD_binding_10 PF13460.1 KEZ41306.1 - 4.9e-12 46.2 0.0 5.6e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KEZ41306.1 - 0.0043 16.9 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KEZ41306.1 - 0.056 13.7 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KEZ41306.1 - 0.099 12.0 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEZ41306.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SKG6 PF08693.5 KEZ41307.1 - 0.0012 18.0 4.8 0.0021 17.3 3.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Protocadherin PF08374.6 KEZ41307.1 - 0.12 12.0 0.2 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 Protocadherin Sugar_tr PF00083.19 KEZ41308.1 - 1.5e-119 399.5 22.0 1.7e-119 399.3 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41308.1 - 5.9e-22 77.8 36.9 1.7e-14 53.3 9.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_synthase PF02540.12 KEZ41309.1 - 3.7e-18 65.3 0.0 7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 KEZ41309.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase His_Phos_2 PF00328.17 KEZ41310.1 - 4.7e-19 68.9 3.2 8.4e-17 61.5 0.2 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) IncA PF04156.9 KEZ41310.1 - 0.0013 18.3 0.0 0.12 12.0 0.1 2.5 2 0 0 2 2 2 1 IncA protein O-antigen_lig PF13425.1 KEZ41310.1 - 0.049 13.6 0.7 0.46 10.4 0.1 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF1469 PF07332.6 KEZ41310.1 - 0.096 12.4 0.6 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF3592 PF12158.3 KEZ41310.1 - 1.8 8.3 4.5 16 5.2 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) Mucin PF01456.12 KEZ41311.1 - 0.0014 18.4 10.9 0.0028 17.4 7.6 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein SpoIIIAH PF12685.2 KEZ41311.1 - 0.0071 15.8 0.3 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein Shisa PF13908.1 KEZ41311.1 - 0.025 14.7 0.4 0.025 14.7 0.3 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Tad PF13400.1 KEZ41311.1 - 0.28 11.2 3.1 0.44 10.6 2.2 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like OAD_gamma PF04277.8 KEZ41311.1 - 0.37 11.1 1.7 1.5 9.2 1.2 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pol_alpha_B_N PF08418.5 KEZ41311.1 - 5.9 6.3 9.9 8.5 5.8 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 KEZ41312.1 - 1.8e-38 132.1 0.0 2.2e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41312.1 - 5.1e-14 51.9 0.0 7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ41312.1 - 1.6e-05 24.8 0.0 0.0016 18.2 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEZ41312.1 - 0.041 12.6 0.1 0.061 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro_61 PF03443.9 KEZ41313.1 - 1.9e-15 57.3 0.1 2.7e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.2 KEZ41313.1 - 1.1e-13 51.3 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41313.1 - 5.2e-13 48.0 0.1 8.2e-07 28.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 KEZ41313.1 - 1.1e-09 37.5 0.0 0.00016 21.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KEZ41313.1 - 2.6e-09 37.3 0.0 1.2e-07 32.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ41313.1 - 1.7e-07 31.2 0.0 9e-06 25.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Prok-E2_C PF14459.1 KEZ41313.1 - 0.081 13.0 0.2 0.18 11.8 0.1 1.6 1 1 1 2 2 2 0 Prokaryotic E2 family C p450 PF00067.17 KEZ41314.1 - 4.9e-19 68.2 0.0 5.3e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 KEZ41315.1 - 7.6e-97 317.8 2.4 2.8e-16 59.6 0.0 9.2 3 1 5 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41315.1 - 1.6e-70 229.5 34.1 7.8e-05 22.2 0.0 19.4 20 0 0 20 20 19 15 Ankyrin repeat Ank_3 PF13606.1 KEZ41315.1 - 8.1e-57 183.4 11.0 0.0062 16.6 0.0 18.5 18 0 0 18 18 18 12 Ankyrin repeat Ank_4 PF13637.1 KEZ41315.1 - 6e-51 169.9 8.7 2.1e-06 28.0 0.0 14.1 7 4 7 14 14 14 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ41315.1 - 6.6e-41 137.4 19.9 3.8e-05 23.7 0.0 12.7 6 4 7 14 14 14 10 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ41315.1 - 9.3e-07 28.6 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ41315.1 - 1.8e-05 24.8 0.0 8.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ41315.1 - 6.8e-05 23.0 0.0 0.00052 20.1 0.0 2.5 2 1 1 3 3 3 1 AAA domain VGCC_beta4Aa_N PF12052.3 KEZ41315.1 - 0.041 13.7 0.3 0.15 11.9 0.2 2.0 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal AAA_33 PF13671.1 KEZ41315.1 - 0.1 12.4 0.0 0.34 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 KEZ41315.1 - 0.14 11.9 0.8 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus 3Beta_HSD PF01073.14 KEZ41316.1 - 6e-54 182.6 0.0 7.7e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ41316.1 - 1.7e-30 106.2 0.2 2.5e-30 105.6 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEZ41316.1 - 2.7e-13 49.4 0.2 1.5e-10 40.4 0.1 2.4 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KEZ41316.1 - 3.4e-10 40.2 0.1 5.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEZ41316.1 - 2.1e-06 26.8 0.4 6.7e-06 25.1 0.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEZ41316.1 - 4.7e-06 25.7 0.1 6.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KEZ41316.1 - 0.0025 17.7 0.1 0.018 14.9 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41316.1 - 0.003 17.2 0.1 0.029 14.0 0.1 2.5 1 1 0 1 1 1 1 KR domain CrtC PF07143.6 KEZ41316.1 - 0.0034 16.7 0.0 0.0073 15.6 0.0 1.5 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) NmrA PF05368.8 KEZ41316.1 - 0.052 12.8 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family p450 PF00067.17 KEZ41317.1 - 1.5e-34 119.3 0.0 2.6e-34 118.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KEZ41318.1 - 2.6e-36 125.1 0.0 4.2e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41318.1 - 2.3e-20 72.7 0.0 3.3e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ41318.1 - 0.0017 17.3 0.0 0.096 11.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like FHA PF00498.21 KEZ41318.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 FHA domain Protoglobin PF11563.3 KEZ41319.1 - 2.6e-53 179.9 0.2 3.2e-53 179.6 0.1 1.1 1 0 0 1 1 1 1 Protoglobin SET PF00856.23 KEZ41320.1 - 1.5e-10 41.5 0.3 6.5e-10 39.5 0.2 2.0 1 1 0 1 1 1 1 SET domain OTT_1508_deam PF14441.1 KEZ41321.1 - 4e-17 62.3 0.0 7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-C2H2_4 PF13894.1 KEZ41322.1 - 0.0082 16.4 1.9 0.13 12.6 0.4 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ41322.1 - 0.15 12.4 1.9 1.3 9.5 0.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type SPDY PF03771.11 KEZ41323.1 - 0.18 11.3 0.4 0.23 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF317) Resistin PF06954.6 KEZ41323.1 - 0.48 10.7 6.0 0.58 10.4 4.2 1.1 1 0 0 1 1 1 0 Resistin GASA PF02704.9 KEZ41323.1 - 1.9 8.5 13.6 3.9 7.5 9.4 1.6 1 1 0 1 1 1 0 Gibberellin regulated protein Exo_endo_phos PF03372.18 KEZ41324.1 - 2.8e-15 56.9 0.7 6.6e-15 55.7 0.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 KEZ41325.1 - 8.4e-65 218.4 0.0 9.8e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41325.1 - 7.9e-31 107.0 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ41325.1 - 9.5e-06 24.7 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ41325.1 - 0.00063 19.5 0.1 0.059 13.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEZ41325.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.13 KEZ41326.1 - 1.9e-45 154.9 0.0 3e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 KEZ41326.1 - 2e-05 24.6 0.2 0.00028 20.9 0.4 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KEZ41326.1 - 2.8e-05 23.6 2.6 0.0028 17.4 0.4 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 KEZ41326.1 - 0.00014 20.8 0.5 0.029 13.6 0.4 3.3 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 KEZ41326.1 - 0.018 14.3 1.4 0.063 12.6 1.0 2.0 1 0 0 1 1 1 0 EF hand CNH PF00780.17 KEZ41327.1 - 1.2e-66 224.9 0.0 2.4e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KEZ41327.1 - 4.8e-31 108.0 0.8 8.5e-31 107.2 0.6 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KEZ41327.1 - 1.7e-11 44.1 0.0 1.2e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KEZ41327.1 - 0.00013 22.1 0.0 0.0005 20.2 0.0 2.1 1 0 0 1 1 1 1 PH domain Sod_Cu PF00080.15 KEZ41328.1 - 3.9e-46 156.7 4.4 4.5e-46 156.5 3.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 KEZ41329.1 - 1.6e-95 319.5 3.0 1.9e-95 319.3 2.1 1.0 1 0 0 1 1 1 1 Transaldolase Pet191_N PF10203.4 KEZ41330.1 - 2.5e-27 94.7 2.5 3.3e-27 94.3 1.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KEZ41330.1 - 0.6 9.9 3.2 5.1 6.9 0.6 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like FbpA PF05833.6 KEZ41331.1 - 7.4e-37 126.9 1.4 7.4e-37 126.9 1.0 2.7 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 KEZ41331.1 - 9.1e-33 112.2 0.7 2.6e-32 110.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 KEZ41331.1 - 2.8e-20 71.9 0.1 6.5e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Methyltransf_2 PF00891.13 KEZ41332.1 - 1e-32 113.2 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEZ41332.1 - 0.00062 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KEZ41332.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.17 KEZ41333.1 - 6.6e-42 143.5 0.0 8.7e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 A_deamin PF02137.13 KEZ41334.1 - 1.3e-58 198.9 0.0 1.6e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NAC PF01849.13 KEZ41335.1 - 7.9e-22 76.5 0.2 3.7e-21 74.3 0.1 2.0 2 0 0 2 2 2 1 NAC domain CBP4 PF07960.6 KEZ41336.1 - 2.4e-32 111.2 2.1 2.8e-32 111.0 1.5 1.0 1 0 0 1 1 1 1 CBP4 Sel1 PF08238.7 KEZ41337.1 - 1.7e-41 139.6 36.7 5.1e-07 30.1 0.1 8.1 8 0 0 8 8 8 7 Sel1 repeat FIST_C PF10442.4 KEZ41337.1 - 0.0078 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 FIST C domain TPR_6 PF13174.1 KEZ41337.1 - 0.049 14.1 5.5 0.54 10.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat hEGF PF12661.2 KEZ41338.1 - 0.013 15.5 2.4 0.027 14.5 1.6 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_2 PF07974.8 KEZ41338.1 - 5.2 7.3 10.8 9.4 6.5 7.5 1.4 1 0 0 1 1 1 0 EGF-like domain PTCB-BRCT PF12738.2 KEZ41339.1 - 3.1e-12 46.1 0.1 6.4e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KEZ41339.1 - 3.4e-11 43.1 0.0 6.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 KEZ41339.1 - 2.1e-05 24.5 0.0 5.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 KEZ41339.1 - 0.039 13.6 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) U79_P34 PF03064.11 KEZ41339.1 - 0.74 9.2 4.7 1.1 8.7 3.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 EAF PF09816.4 KEZ41340.1 - 5.2e-19 68.2 0.0 1.1e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CDC27 PF09507.5 KEZ41340.1 - 0.16 11.1 21.4 0.26 10.4 14.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dicty_REP PF05086.7 KEZ41340.1 - 4.4 4.9 5.2 7.6 4.1 3.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neisseria_TspB PF05616.8 KEZ41340.1 - 5 5.3 14.1 7.5 4.7 9.7 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein NT-C2 PF10358.4 KEZ41341.1 - 8.3e-22 77.2 0.0 1.6e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins HSP70 PF00012.15 KEZ41342.1 - 1.1e-78 264.7 3.5 1.4e-78 264.2 2.4 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ41342.1 - 6.2e-06 25.0 0.1 1.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 MreB/Mbl protein Nucleoplasmin PF03066.10 KEZ41342.1 - 0.0075 15.7 0.7 0.017 14.6 0.5 1.6 1 0 0 1 1 1 1 Nucleoplasmin PilM_2 PF11104.3 KEZ41342.1 - 0.028 13.3 0.9 3.7 6.3 0.0 3.1 2 1 1 3 3 3 0 Type IV pilus assembly protein PilM; BTV_NS2 PF04514.7 KEZ41342.1 - 0.055 12.3 1.3 0.59 8.9 0.2 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 FAM176 PF14851.1 KEZ41342.1 - 0.26 10.9 2.0 0.28 10.8 0.5 1.7 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.8 KEZ41342.1 - 0.51 9.9 8.8 0.23 11.0 2.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region AAA_12 PF13087.1 KEZ41344.1 - 5.2e-23 81.4 0.0 6.1e-22 77.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KEZ41344.1 - 3e-10 40.0 0.0 1.9e-09 37.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KEZ41344.1 - 2.2e-06 27.3 0.0 0.0006 19.3 0.0 2.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 KEZ41344.1 - 4.7e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 KEZ41344.1 - 0.00041 19.8 0.0 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEZ41344.1 - 0.18 11.3 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KEZ41345.1 - 3.8e-08 33.1 12.0 6.4e-08 32.3 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C_2 PF13410.1 KEZ41345.1 - 0.023 14.5 0.2 0.045 13.6 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glycos_transf_N PF04413.11 KEZ41345.1 - 0.088 11.9 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Annexin PF00191.15 KEZ41346.1 - 8.9e-19 67.1 1.9 7.2e-06 25.8 0.0 4.5 4 0 0 4 4 4 4 Annexin Oxysterol_BP PF01237.13 KEZ41348.1 - 5.7e-128 426.3 0.0 1.6e-127 424.9 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 KEZ41348.1 - 6.3e-18 64.8 0.0 9.6e-11 41.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41348.1 - 6.8e-18 63.4 0.1 4.5e-06 26.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KEZ41348.1 - 2.9e-16 57.9 0.2 4.9e-05 23.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEZ41348.1 - 3.2e-16 59.3 0.1 6.3e-09 36.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ41348.1 - 8.1e-16 57.6 2.1 7.9e-08 32.3 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.24 KEZ41348.1 - 1.4e-11 44.5 0.3 3.3e-11 43.2 0.2 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEZ41348.1 - 1.4e-08 34.9 1.1 1.4e-08 34.9 0.8 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 KEZ41348.1 - 3.2e-08 33.5 1.0 1e-07 31.9 0.7 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.1 KEZ41349.1 - 3.3e-45 154.8 2.1 3.9e-45 154.5 1.4 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KEZ41349.1 - 1e-24 86.6 0.0 1.1e-17 63.9 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase AfsA PF03756.8 KEZ41349.1 - 0.13 11.9 0.2 1 9.0 0.1 2.2 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain DUF2763 PF10961.3 KEZ41350.1 - 1.3 9.4 6.4 0.32 11.4 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) Secretin_N_2 PF07655.8 KEZ41350.1 - 4.9 7.6 10.0 0.57 10.6 3.5 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain AMP-binding PF00501.23 KEZ41351.1 - 1.8e-77 260.5 0.0 2.3e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ41351.1 - 4.4e-12 46.7 2.8 6.2e-12 46.2 0.3 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 KEZ41352.1 - 2.5e-22 79.6 0.0 3.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sialidase PF02973.11 KEZ41352.1 - 0.036 13.0 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Sialidase, N-terminal domain Asp PF00026.18 KEZ41353.1 - 5.3e-49 167.1 0.0 7e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ41353.1 - 6.7e-06 26.1 0.1 3e-05 24.0 0.1 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEZ41353.1 - 0.002 18.5 3.5 2.7 8.5 0.8 3.4 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KEZ41353.1 - 0.016 14.7 0.2 0.32 10.5 0.1 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal ATP12 PF07542.6 KEZ41354.1 - 1.5e-29 102.4 0.2 2.3e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DUF2183 PF09949.4 KEZ41354.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Abhydrolase_2 PF02230.11 KEZ41356.1 - 2.2e-59 200.5 0.0 2.7e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KEZ41356.1 - 1.1e-09 38.2 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ41356.1 - 0.00012 22.0 0.6 0.0027 17.6 0.4 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ41356.1 - 0.01 15.0 0.2 1.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family FSH1 PF03959.8 KEZ41356.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 KEZ41356.1 - 0.046 13.3 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 KEZ41356.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 KEZ41356.1 - 0.054 13.0 0.0 0.17 11.4 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Fumble PF03630.9 KEZ41357.1 - 1.5e-132 441.5 0.0 1.2e-131 438.5 0.0 1.9 1 1 0 1 1 1 1 Fumble 2OG-FeII_Oxy_3 PF13640.1 KEZ41358.1 - 1.5e-07 31.8 0.0 2.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEZ41358.1 - 0.00075 19.0 0.1 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RdRP PF05183.7 KEZ41359.1 - 2.3e-179 597.8 0.0 3e-179 597.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD-oxidase_C PF02913.14 KEZ41360.1 - 2.1e-63 213.9 0.0 3e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEZ41360.1 - 1.9e-34 118.1 0.0 4e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain YfdX PF10938.3 KEZ41360.1 - 0.022 14.4 0.3 0.94 9.1 0.2 2.2 2 0 0 2 2 2 0 YfdX protein Ribosomal_S4e PF00900.15 KEZ41361.1 - 1.2e-30 105.0 1.2 1.3e-30 104.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 KEZ41361.1 - 1.7e-16 59.7 2.0 3.7e-16 58.6 1.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KEZ41361.1 - 1.3e-06 27.7 0.1 2.3e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KEZ41361.1 - 6e-05 22.6 0.4 6e-05 22.6 0.3 3.1 4 0 0 4 4 4 1 KOW motif Septin PF00735.13 KEZ41363.1 - 2.1e-31 108.9 0.0 1.9e-11 43.5 0.0 3.1 3 0 0 3 3 3 3 Septin G-alpha PF00503.15 KEZ41363.1 - 0.0098 14.6 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 KEZ41363.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KEZ41363.1 - 0.025 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3313 PF11769.3 KEZ41363.1 - 0.033 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Miro PF08477.8 KEZ41363.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.8 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 KEZ41363.1 - 0.12 12.2 0.1 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase DGF-1_C PF11040.3 KEZ41363.1 - 0.13 12.1 1.4 0.95 9.3 0.1 2.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus ABC1 PF03109.11 KEZ41364.1 - 8.9e-17 61.1 0.0 5.7e-16 58.5 0.0 2.2 1 1 0 1 1 1 1 ABC1 family APH PF01636.18 KEZ41364.1 - 0.00076 19.2 0.8 0.0043 16.8 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEZ41364.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SUR7 PF06687.7 KEZ41365.1 - 1.7e-22 80.0 14.9 2.1e-22 79.7 10.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family CobD_Cbib PF03186.8 KEZ41365.1 - 0.12 11.4 2.4 0.19 10.7 1.6 1.3 1 0 0 1 1 1 0 CobD/Cbib protein Roughex PF06020.6 KEZ41366.1 - 0.023 13.4 0.1 0.037 12.7 0.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Smg4_UPF3 PF03467.10 KEZ41367.1 - 1.3e-20 74.1 0.0 5.8e-20 72.0 0.0 2.2 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 KEZ41367.1 - 9.5e-06 25.1 0.0 3.9e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41367.1 - 3.6e-05 23.6 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41367.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 KEZ41368.1 - 2.7e-38 131.3 0.0 1.6e-37 128.8 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.1 KEZ41369.1 - 5.9e-08 31.9 0.2 0.013 15.3 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KEZ41369.1 - 0.00013 20.9 0.6 0.0013 17.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KEZ41369.1 - 0.00034 20.7 0.4 0.00034 20.7 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KEZ41369.1 - 0.004 16.4 0.2 0.11 11.8 0.1 2.6 2 0 0 2 2 2 1 EF hand PDGF_N PF04692.8 KEZ41369.1 - 0.037 14.5 0.2 0.088 13.3 0.1 1.7 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region EF-hand_8 PF13833.1 KEZ41369.1 - 0.065 12.8 0.1 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair ORC6 PF05460.8 KEZ41370.1 - 3.6e-33 115.1 4.7 1.9e-32 112.7 1.6 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) Chitin_bind_3 PF03067.10 KEZ41371.1 - 5.8e-08 33.2 0.0 8.9e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 Chitin binding domain Integrin_alpha PF00357.15 KEZ41372.1 - 0.0049 16.5 1.8 2.1 8.3 0.1 2.9 2 0 0 2 2 2 2 Integrin alpha cytoplasmic region SKG6 PF08693.5 KEZ41372.1 - 0.0056 15.9 0.2 0.016 14.4 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4238 PF14022.1 KEZ41373.1 - 1.5e-29 103.0 0.2 2.5e-29 102.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Fungal_trans PF04082.13 KEZ41374.1 - 1.1e-29 103.1 0.0 3e-29 101.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41374.1 - 2.1e-09 37.1 7.6 3.6e-09 36.3 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 KEZ41374.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Med3 PF11593.3 KEZ41374.1 - 0.24 10.6 10.6 0.53 9.4 7.4 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans PF04082.13 KEZ41375.1 - 1e-42 145.8 0.0 1.7e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41375.1 - 1e-08 34.8 6.4 2.2e-08 33.8 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.1 KEZ41376.1 - 4.1e-15 55.3 16.5 2.7e-14 52.7 5.2 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 KEZ41376.1 - 2.8e-11 42.8 8.0 1e-09 37.8 2.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ41376.1 - 2.1e-07 30.4 14.0 8.3e-06 25.3 5.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEZ41376.1 - 9.3e-07 28.8 2.7 9.3e-07 28.8 1.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEZ41376.1 - 9.7e-07 28.7 15.0 3.8e-06 26.8 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ41376.1 - 5.4e-06 26.0 10.5 3.3e-05 23.5 3.0 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-Apc11 PF12861.2 KEZ41376.1 - 4.9e-05 23.0 4.1 0.00051 19.8 0.9 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 KEZ41376.1 - 0.0002 21.2 4.8 0.0015 18.4 1.6 2.5 2 0 0 2 2 2 1 zinc-finger Baculo_RING PF05883.6 KEZ41376.1 - 0.0067 16.2 1.3 0.0067 16.2 0.9 1.9 2 0 0 2 2 2 1 Baculovirus U-box/Ring-like domain GCC2_GCC3 PF07699.8 KEZ41376.1 - 0.28 10.7 2.3 0.31 10.6 0.2 2.0 2 0 0 2 2 2 0 GCC2 and GCC3 DZR PF12773.2 KEZ41376.1 - 0.33 10.7 4.8 0.75 9.6 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 KEZ41376.1 - 1 9.1 9.0 3.5 7.3 4.1 2.6 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 KEZ41376.1 - 2.6 7.9 11.8 4.2 7.3 0.4 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KEZ41376.1 - 2.8 7.6 13.0 2.6 7.6 2.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 KEZ41376.1 - 5.8 6.8 9.6 0.55 10.1 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 KEZ41376.1 - 7.8 6.1 9.3 0.37 10.3 2.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Fis1_TPR_C PF14853.1 KEZ41377.1 - 2.2e-25 88.2 0.8 3.6e-25 87.5 0.5 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KEZ41377.1 - 4.8e-17 60.9 0.0 7.7e-17 60.2 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 KEZ41377.1 - 0.0047 16.7 0.9 0.0081 16.0 0.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ41377.1 - 0.0061 17.2 0.4 0.012 16.2 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.6 KEZ41378.1 - 7.9e-41 138.4 1.3 1.3e-39 134.5 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 KEZ41378.1 - 0.036 13.2 0.9 0.045 12.9 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Troponin PF00992.15 KEZ41378.1 - 0.14 12.2 5.0 0.21 11.6 3.4 1.3 1 0 0 1 1 1 0 Troponin Scaffolding_pro PF11418.3 KEZ41378.1 - 0.16 12.2 1.9 0.19 12.0 0.7 1.7 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF4164 PF13747.1 KEZ41378.1 - 1.8 8.7 12.4 19 5.4 8.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Death PF00531.17 KEZ41379.1 - 0.0077 15.9 0.2 0.11 12.2 0.1 2.4 2 0 0 2 2 2 1 Death domain RSN1_TM PF13967.1 KEZ41380.1 - 0.32 10.5 0.6 0.63 9.5 0.4 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DcpS_C PF11969.3 KEZ41381.1 - 4.7e-32 110.6 0.1 7.2e-32 110.0 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KEZ41381.1 - 1.9e-27 95.8 0.0 3.1e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal GILT PF03227.11 KEZ41382.1 - 4.7e-13 48.9 0.1 6.7e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_2 PF03727.11 KEZ41383.1 - 1.3e-17 63.8 0.0 2.8e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KEZ41383.1 - 0.084 12.1 0.0 0.7 9.1 0.0 2.0 2 0 0 2 2 2 0 Hexokinase Myb_Cef PF11831.3 KEZ41384.1 - 6.4e-59 198.9 7.1 6.4e-59 198.9 4.9 3.0 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KEZ41384.1 - 9.7e-22 76.7 4.9 1.1e-10 41.4 0.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEZ41384.1 - 4e-21 74.8 9.6 1.7e-14 53.6 2.2 4.0 3 1 1 4 4 4 2 Myb-like DNA-binding domain Rap1_C PF11626.3 KEZ41384.1 - 0.025 14.4 0.6 0.71 9.7 0.0 2.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.11 KEZ41385.1 - 1.4e-29 102.9 15.0 1.2e-21 76.8 4.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ41385.1 - 1.6e-10 40.1 0.2 3e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.13 KEZ41385.1 - 1.5 7.2 5.3 0.59 8.5 0.1 2.5 2 1 1 3 3 3 0 Reduced folate carrier HIT PF01230.18 KEZ41386.1 - 9.7e-19 67.7 0.0 1.5e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEZ41386.1 - 0.0048 17.1 0.1 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding UCR_Fe-S_N PF10399.4 KEZ41387.1 - 0.039 13.1 3.7 0.093 11.9 1.8 1.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 KEZ41387.1 - 1.6 8.9 6.5 1.7 8.8 3.1 2.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence RFXA_RFXANK_bdg PF15289.1 KEZ41388.1 - 0.34 11.1 1.5 4.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain CPSase_L_D2 PF02786.12 KEZ41389.1 - 7.3e-115 381.5 1.0 1.1e-84 282.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 KEZ41389.1 - 5.6e-43 146.0 0.0 1.4e-42 144.7 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.17 KEZ41389.1 - 1.2e-42 144.5 0.0 2.6e-42 143.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 KEZ41389.1 - 3.7e-42 142.9 0.2 9e-42 141.7 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KEZ41389.1 - 5.9e-42 142.2 0.0 2.1e-20 72.8 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 KEZ41389.1 - 7.6e-42 142.9 0.0 2.4e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I ATP-grasp_4 PF13535.1 KEZ41389.1 - 8e-37 126.7 0.3 3e-22 79.2 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 KEZ41389.1 - 1.5e-33 115.8 0.0 3.3e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 KEZ41389.1 - 4e-26 91.5 0.0 3.2e-15 55.6 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KEZ41389.1 - 5.2e-23 80.7 0.0 2e-22 78.9 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.17 KEZ41389.1 - 4.1e-18 65.3 0.3 8.1e-09 35.0 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEZ41389.1 - 6.3e-17 61.6 1.7 3.9e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KEZ41389.1 - 6.1e-08 32.6 1.6 0.0011 18.9 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KEZ41389.1 - 1.2e-05 24.9 0.7 0.16 11.4 0.1 3.2 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_C26 PF07722.8 KEZ41389.1 - 0.00013 21.5 0.0 0.013 14.9 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 PNPOx_C PF10590.4 KEZ41390.1 - 4.8e-21 73.9 0.8 1.8e-20 72.1 0.8 1.8 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 KEZ41390.1 - 5.7e-17 61.5 0.0 9.7e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 KEZ41390.1 - 0.0042 17.3 0.0 0.013 15.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M28 PF04389.12 KEZ41391.1 - 6.3e-26 91.1 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEZ41391.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AFG1_ATPase PF03969.11 KEZ41392.1 - 8.9e-96 320.8 0.0 4.1e-91 305.4 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KEZ41392.1 - 9.7e-06 25.6 3.2 0.02 14.8 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain Bac_DnaA PF00308.13 KEZ41392.1 - 0.00037 20.2 0.6 0.44 10.1 0.0 2.9 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_22 PF13401.1 KEZ41392.1 - 0.012 15.7 0.0 0.072 13.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KEZ41392.1 - 0.032 14.2 0.0 0.52 10.3 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 KEZ41392.1 - 0.056 13.1 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 KEZ41392.1 - 0.082 13.1 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEZ41392.1 - 0.13 12.4 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Cu_bind_like PF02298.12 KEZ41393.1 - 0.0019 17.9 1.3 0.0058 16.3 0.3 2.1 2 1 0 2 2 2 1 Plastocyanin-like domain Copper-bind PF00127.15 KEZ41393.1 - 0.031 14.5 0.5 0.1 12.8 0.4 1.8 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Menin PF05053.8 KEZ41393.1 - 1.4 7.0 3.2 1.9 6.5 2.2 1.2 1 0 0 1 1 1 0 Menin bZIP_1 PF00170.16 KEZ41394.1 - 0.0053 16.6 4.6 0.017 15.0 3.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor Metallophos PF00149.23 KEZ41395.1 - 2.8e-36 124.7 0.4 4.1e-29 101.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Sld5 PF05916.6 KEZ41398.1 - 5e-26 91.1 0.0 7.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein PPP4R2 PF09184.6 KEZ41399.1 - 2.5 7.5 17.4 4 6.9 12.1 1.4 1 0 0 1 1 1 0 PPP4R2 PAN_1 PF00024.21 KEZ41400.1 - 2.3e-09 36.8 0.6 0.00035 20.2 0.1 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.1 KEZ41400.1 - 2e-06 27.4 5.2 0.00018 21.1 1.1 2.5 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.6 KEZ41400.1 - 0.00036 20.3 3.1 0.0036 17.1 0.3 2.3 2 0 0 2 2 2 1 PAN-like domain PQ-loop PF04193.9 KEZ41401.1 - 3.8e-13 48.7 1.5 7.9e-13 47.7 0.5 2.0 1 1 1 2 2 2 1 PQ loop repeat Peptidase_M50 PF02163.17 KEZ41401.1 - 0.029 13.3 0.7 0.042 12.7 0.5 1.4 1 0 0 1 1 1 0 Peptidase family M50 DUF3995 PF13160.1 KEZ41401.1 - 0.27 11.3 7.0 0.086 12.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF2975 PF11188.3 KEZ41401.1 - 0.98 9.1 4.5 4.3 7.0 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) MMS1_N PF10433.4 KEZ41402.1 - 4.7e-77 259.2 0.0 8.8e-77 258.3 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KEZ41402.1 - 7.8e-53 179.6 0.0 1.1e-51 175.8 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region Cuticle_1 PF08140.6 KEZ41402.1 - 0.063 13.1 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Rieske PF00355.21 KEZ41403.1 - 2e-18 65.7 0.0 3.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 KEZ41403.1 - 3.3e-18 65.6 0.2 6.1e-18 64.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region ProRS-C_1 PF09180.6 KEZ41405.1 - 8.4e-22 76.8 0.3 1.9e-21 75.7 0.2 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KEZ41405.1 - 4.6e-21 75.1 0.0 8.9e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEZ41405.1 - 1.1e-16 60.5 0.0 3.3e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain DUF919 PF06034.6 KEZ41405.1 - 0.052 13.1 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Cpn60_TCP1 PF00118.19 KEZ41406.1 - 7.1e-145 483.3 11.1 8.1e-145 483.1 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_int_SAM_1 PF02899.12 KEZ41406.1 - 0.21 11.7 0.8 2.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain SKG6 PF08693.5 KEZ41407.1 - 0.054 12.8 0.5 0.18 11.1 0.3 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AF-4 PF05110.8 KEZ41407.1 - 6.4 4.4 10.6 8.7 4.0 7.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Mucin PF01456.12 KEZ41407.1 - 7.2 6.3 24.0 0.2 11.4 11.5 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein RTA1 PF04479.8 KEZ41408.1 - 2.5e-28 99.1 1.8 3.1e-28 98.7 1.2 1.1 1 0 0 1 1 1 1 RTA1 like protein RRP14 PF15459.1 KEZ41408.1 - 4 7.5 12.1 8.3 6.5 8.4 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Ion_trans PF00520.26 KEZ41409.1 - 1.2e-05 24.6 19.9 1.4e-05 24.4 12.4 2.2 1 1 0 1 1 1 1 Ion transport protein Peptidase_S9 PF00326.16 KEZ41410.1 - 4.7e-45 153.4 0.0 6.8e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ41410.1 - 1.3e-07 31.4 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ41410.1 - 0.00035 20.2 0.0 0.0065 16.0 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KEZ41410.1 - 0.0034 17.2 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein AXE1 PF05448.7 KEZ41410.1 - 0.09 11.2 0.0 1.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KEZ41410.1 - 0.14 11.5 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 KEZ41410.1 - 0.15 10.3 0.0 0.34 9.1 0.0 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II EAP30 PF04157.11 KEZ41411.1 - 2e-56 190.6 0.0 2.6e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KEZ41411.1 - 1.2e-22 79.5 0.0 2.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 KEZ41411.1 - 0.0003 20.2 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain SAC3_GANP PF03399.11 KEZ41412.1 - 6.5e-64 215.2 0.1 9.2e-64 214.7 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEZ41412.1 - 0.00087 19.0 0.0 0.0024 17.6 0.0 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 KEZ41413.1 - 1.2e-27 95.0 0.0 3.4e-13 48.7 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KEZ41413.1 - 2.6e-17 62.1 0.1 2.1e-07 30.4 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 KEZ41413.1 - 1.4e-14 53.7 0.1 4.1e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.12 KEZ41413.1 - 3.7e-11 42.3 0.0 1.4e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 KEZ41413.1 - 2.9e-10 39.6 0.1 4.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.3 KEZ41413.1 - 0.0049 16.5 0.0 0.016 14.8 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Thymidylat_synt PF00303.14 KEZ41414.1 - 6.8e-118 392.5 0.0 7.8e-118 392.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase adh_short PF00106.20 KEZ41415.1 - 1.5e-26 93.3 0.3 1.5e-26 93.3 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ41415.1 - 3e-17 63.2 0.0 3.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ41415.1 - 1.7e-06 27.7 0.1 2.7e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEZ41415.1 - 2.4e-05 24.4 0.1 6e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KEZ41415.1 - 0.0028 16.9 0.1 0.0056 15.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 KEZ41415.1 - 0.006 16.1 0.1 0.014 14.9 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KEZ41415.1 - 0.022 14.7 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_28 PF03033.15 KEZ41415.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Epimerase PF01370.16 KEZ41415.1 - 0.096 12.1 0.1 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KEZ41415.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 KEZ41415.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF2611 PF11022.3 KEZ41416.1 - 5.4e-26 90.4 0.1 5.9e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 KEZ41417.1 - 1.5e-67 226.1 0.0 1.8e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.11 KEZ41418.1 - 2.6e-16 59.1 16.0 1.2e-09 37.8 5.1 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KEZ41418.1 - 0.68 9.8 11.3 0.11 12.3 2.7 2.3 2 0 0 2 2 2 0 IBR domain Rad4 PF03835.10 KEZ41419.1 - 5.9e-33 113.3 0.1 1.7e-32 111.8 0.1 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KEZ41419.1 - 2.1e-25 88.2 0.2 4.9e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KEZ41419.1 - 5.8e-21 73.7 0.3 1.1e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KEZ41419.1 - 2.3e-15 56.6 6.6 2.4e-14 53.3 0.1 4.4 3 1 1 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KEZ41419.1 - 0.013 15.6 0.0 0.052 13.7 0.0 2.1 1 1 0 1 1 1 0 Transglutaminase-like superfamily IBR PF01485.16 KEZ41420.1 - 0.0027 17.5 5.6 0.0027 17.5 3.9 2.6 2 0 0 2 2 2 2 IBR domain DUF2036 PF09724.4 KEZ41421.1 - 1.3e-08 34.3 0.0 1.4e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RhoGEF PF00621.15 KEZ41422.1 - 1.1e-25 90.5 0.8 3.6e-24 85.6 0.0 2.3 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 KEZ41422.1 - 0.0095 15.4 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) HORMA PF02301.13 KEZ41423.1 - 6.5e-23 81.3 0.0 8.8e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain PI31_Prot_N PF11566.3 KEZ41424.1 - 1.5e-29 102.6 0.0 1.8e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KEZ41424.1 - 6.6e-17 61.9 19.9 6.6e-17 61.9 13.8 3.1 3 1 0 3 3 3 1 PI31 proteasome regulator Myosin_TH1 PF06017.8 KEZ41424.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Myosin tail IBN_N PF03810.14 KEZ41425.1 - 1e-12 47.8 0.5 1.6e-11 43.9 0.1 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain SQS_PSY PF00494.14 KEZ41425.1 - 0.00043 19.6 0.2 0.00093 18.5 0.1 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase HEAT_2 PF13646.1 KEZ41425.1 - 0.00059 20.0 16.9 0.11 12.8 0.2 6.0 6 1 0 6 6 6 2 HEAT repeats HEAT PF02985.17 KEZ41425.1 - 0.003 17.5 3.5 2.4 8.4 0.1 5.2 5 0 0 5 5 5 1 HEAT repeat CAS_CSE1 PF03378.10 KEZ41425.1 - 0.0098 14.2 0.0 0.019 13.2 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KEZ41425.1 - 0.029 12.9 0.1 0.096 11.2 0.0 1.9 3 0 0 3 3 3 0 Cse1 Xpo1 PF08389.7 KEZ41425.1 - 0.049 13.5 0.0 1.9 8.3 0.0 3.3 3 0 0 3 3 3 0 Exportin 1-like protein DUF2742 PF10888.3 KEZ41426.1 - 0.046 13.6 0.2 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Metallophos PF00149.23 KEZ41428.1 - 3.4e-38 131.0 0.6 4.5e-38 130.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 KEZ41429.1 - 1.4e-57 194.3 0.2 1.5e-57 194.2 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.8 KEZ41430.1 - 0.003 17.1 0.7 0.01 15.4 0.0 2.2 3 1 0 3 3 3 1 KilA-N domain NAD_binding_2 PF03446.10 KEZ41431.1 - 3.8e-32 111.3 0.0 5.7e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KEZ41431.1 - 1.6e-31 108.8 0.0 2.3e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KEZ41431.1 - 4.9e-07 28.8 0.3 7.9e-07 28.1 0.2 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 3HCDH_N PF02737.13 KEZ41431.1 - 0.055 13.1 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RTA1 PF04479.8 KEZ41432.1 - 8.5e-36 123.5 0.2 1.1e-35 123.1 0.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Adaptin_N PF01602.15 KEZ41433.1 - 1.3e-102 343.8 0.0 1.6e-102 343.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KEZ41433.1 - 7.5e-10 38.9 7.9 6.2e-05 23.2 0.1 4.8 3 1 0 3 3 3 3 HEAT repeats HEAT PF02985.17 KEZ41433.1 - 1.2e-06 28.1 0.2 0.2 11.8 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KEZ41433.1 - 1.6e-06 28.4 7.9 0.0012 19.2 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KEZ41433.1 - 0.011 15.7 0.8 0.59 10.1 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DDHD PF02862.12 KEZ41433.1 - 1.2 8.8 6.1 3.2 7.4 4.2 1.6 1 0 0 1 1 1 0 DDHD domain SDA1 PF05285.7 KEZ41433.1 - 1.9 7.7 29.3 4.4 6.4 20.3 1.6 1 0 0 1 1 1 0 SDA1 Prog_receptor PF02161.10 KEZ41433.1 - 2.4 6.8 11.2 4.8 5.8 7.7 1.4 1 0 0 1 1 1 0 Progesterone receptor Polyoma_lg_T_C PF06431.6 KEZ41433.1 - 8.9 4.8 6.6 14 4.1 4.6 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Nuf2 PF03800.9 KEZ41435.1 - 1.2e-44 151.8 2.5 1.8e-44 151.3 0.1 2.4 2 0 0 2 2 2 1 Nuf2 family DUF3584 PF12128.3 KEZ41435.1 - 7.5 3.7 46.4 29 1.8 32.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4360 PF14273.1 KEZ41436.1 - 1.8e-10 40.7 0.3 2.3e-10 40.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) HAD PF12710.2 KEZ41437.1 - 3.5e-15 56.6 0.1 4.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEZ41437.1 - 3.6e-05 24.0 0.2 0.00015 21.9 0.0 2.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KEZ41437.1 - 0.0052 15.9 0.0 0.052 12.7 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase Lactamase_B_2 PF12706.2 KEZ41437.1 - 0.0091 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UMPH-1 PF05822.7 KEZ41437.1 - 0.031 13.6 0.0 0.11 11.8 0.0 1.9 2 1 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) DAO PF01266.19 KEZ41438.1 - 7.7e-24 84.2 0.3 9.8e-24 83.9 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Globin PF00042.17 KEZ41438.1 - 0.053 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Globin Sorb PF02208.11 KEZ41438.1 - 0.12 11.7 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Sorbin homologous domain Thioredoxin PF00085.15 KEZ41439.1 - 4.2e-27 93.8 0.0 4.9e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEZ41439.1 - 6.4e-09 36.0 0.1 4.3e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEZ41439.1 - 8.9e-08 32.1 0.0 0.00055 19.9 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KEZ41439.1 - 6.4e-06 26.1 0.0 9.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KEZ41439.1 - 1.4e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KEZ41439.1 - 0.00021 20.8 0.1 0.0057 16.2 0.0 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KEZ41439.1 - 0.00066 19.3 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family WH1 PF00568.18 KEZ41439.1 - 0.062 13.0 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 WH1 domain TrbC_Ftype PF09673.5 KEZ41439.1 - 0.076 12.6 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein HyaE PF07449.6 KEZ41439.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE eIF-1a PF01176.14 KEZ41440.1 - 1e-10 40.8 0.0 1.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 KEZ41441.1 - 2.6e-130 434.9 16.7 3e-130 434.7 11.6 1.0 1 0 0 1 1 1 1 ALG3 protein Pkinase PF00069.20 KEZ41442.1 - 1.4e-62 211.2 0.0 2.5e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41442.1 - 2.5e-35 121.8 0.0 4.3e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KEZ41442.1 - 1.2e-28 98.6 25.4 8.1e-17 60.7 2.4 2.8 3 0 0 3 3 3 2 Hr1 repeat Pkinase_C PF00433.19 KEZ41442.1 - 1.7e-14 54.0 2.9 4.7e-14 52.6 2.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain C1_1 PF00130.17 KEZ41442.1 - 1.1e-11 44.3 27.7 1.7e-11 43.6 7.2 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KEZ41442.1 - 0.0017 17.4 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Prok-RING_1 PF14446.1 KEZ41442.1 - 0.0034 17.0 6.9 0.0069 16.1 4.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD PF00628.24 KEZ41442.1 - 0.025 14.2 8.0 0.06 13.0 5.6 1.6 1 0 0 1 1 1 0 PHD-finger PAT1 PF09770.4 KEZ41442.1 - 3.5 5.7 51.3 0.19 9.9 30.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Acyl-CoA_dh_1 PF00441.19 KEZ41443.1 - 2.8e-42 144.3 4.2 4.4e-42 143.7 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEZ41443.1 - 3.5e-29 101.6 0.2 3.7e-28 98.3 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ41443.1 - 2.4e-16 58.9 0.0 4.8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEZ41443.1 - 7.3e-16 58.6 1.4 1.4e-15 57.7 1.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KEZ41443.1 - 0.00013 21.4 0.2 0.00051 19.5 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosom_S12_S23 PF00164.20 KEZ41444.1 - 2.3e-40 136.8 1.0 3e-40 136.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Synthase_beta PF11421.3 KEZ41444.1 - 8.2 7.1 7.7 3.1 8.5 1.1 2.9 3 0 0 3 3 3 0 ATP synthase F1 beta subunit Sin_N PF04801.8 KEZ41445.1 - 3.7e-15 55.7 0.0 7e-15 54.7 0.0 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.4 KEZ41446.1 - 1.6e-226 754.4 14.0 3.1e-226 753.4 9.7 1.4 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 GCN5L1 PF06320.8 KEZ41446.1 - 0.032 14.0 0.5 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Glyco_transf_15 PF01793.11 KEZ41447.1 - 5.3e-140 466.0 9.7 6.4e-140 465.7 6.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 KEZ41447.1 - 0.03 14.1 1.3 0.074 12.8 0.9 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor DUF3824 PF12868.2 KEZ41447.1 - 0.16 12.9 2.7 0.28 12.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) EMP70 PF02990.11 KEZ41448.1 - 7.8e-193 641.6 5.7 1.1e-192 641.1 3.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 KEZ41448.1 - 0.13 12.4 0.0 0.13 12.4 0.0 4.2 3 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding Med4 PF10018.4 KEZ41449.1 - 1.4e-43 148.4 4.9 2.3e-43 147.7 3.4 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Myc_N PF01056.13 KEZ41449.1 - 0.0016 17.6 1.9 0.0026 16.9 1.3 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Caldesmon PF02029.10 KEZ41449.1 - 0.0032 15.9 18.2 0.0032 15.9 12.6 1.7 2 0 0 2 2 2 1 Caldesmon UDPG_MGDP_dh_C PF03720.10 KEZ41449.1 - 0.074 13.2 0.3 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Baculo_PEP_C PF04513.7 KEZ41449.1 - 0.35 10.7 2.2 3.3 7.5 1.5 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med8 PF10232.4 KEZ41449.1 - 0.36 10.2 8.5 0.97 8.9 2.1 2.5 2 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PIN_4 PF13638.1 KEZ41449.1 - 2 8.5 5.2 0.91 9.6 0.3 2.1 2 0 0 2 2 2 0 PIN domain ARGLU PF15346.1 KEZ41449.1 - 6.7 6.4 31.1 0.31 10.7 16.0 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 QCR10 PF09796.4 KEZ41450.1 - 1.2e-16 60.0 0.1 1.5e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 KEZ41450.1 - 0.02 14.5 1.0 0.028 14.1 0.1 1.8 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF3386 PF11866.3 KEZ41450.1 - 0.022 13.9 0.1 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) DIE2_ALG10 PF04922.7 KEZ41451.1 - 8.2e-53 179.7 13.4 2e-32 112.6 0.9 3.2 3 0 0 3 3 3 3 DIE2/ALG10 family U-box PF04564.10 KEZ41452.1 - 1e-19 70.2 0.0 1.7e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KEZ41452.1 - 1.9e-10 40.1 4.3 1e-06 28.3 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEZ41452.1 - 3.1e-07 29.7 4.4 3.6e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ41452.1 - 2.2e-06 27.4 2.0 0.00041 20.3 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ41452.1 - 6.7e-06 25.6 3.3 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ41452.1 - 0.00022 21.1 1.0 0.00065 19.5 0.7 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEZ41452.1 - 0.023 14.5 1.0 3.4 7.6 0.3 2.7 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 KEZ41452.1 - 0.034 14.8 1.1 0.034 14.8 0.7 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Ras PF00071.17 KEZ41453.1 - 9.9e-15 54.2 0.0 5.8e-06 25.7 0.0 3.5 3 1 0 3 3 3 3 Ras family Miro PF08477.8 KEZ41453.1 - 0.0024 18.3 0.0 0.54 10.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein PTR2 PF00854.16 KEZ41454.1 - 7.7e-28 97.3 7.6 6.7e-17 61.3 3.1 2.2 1 1 0 2 2 2 2 POT family Peptidase_C14 PF00656.17 KEZ41455.1 - 6.9e-70 235.5 0.0 8.4e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Ank_2 PF12796.2 KEZ41456.1 - 3.6e-34 116.9 4.6 4.3e-11 43.0 0.1 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41456.1 - 8.1e-27 91.6 8.4 3.1e-06 26.7 0.0 7.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 KEZ41456.1 - 3.9e-21 73.0 4.3 8.4e-05 22.4 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 KEZ41456.1 - 3.7e-20 71.4 2.1 1.1e-07 31.8 0.0 5.4 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ41456.1 - 5.7e-19 68.1 4.2 2.3e-07 31.1 0.1 6.1 5 1 1 6 6 6 3 Ankyrin repeats (many copies) AAA_22 PF13401.1 KEZ41456.1 - 5.1e-06 26.6 0.0 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ41456.1 - 3.4e-05 23.9 0.1 0.00064 19.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain KAP_NTPase PF07693.9 KEZ41456.1 - 0.00034 19.7 0.4 0.00098 18.2 0.0 1.7 1 1 1 2 2 2 1 KAP family P-loop domain NACHT PF05729.7 KEZ41456.1 - 0.0013 18.4 0.2 0.0046 16.6 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 KEZ41456.1 - 0.047 14.4 0.0 0.23 12.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ41456.1 - 0.089 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FHA PF00498.21 KEZ41457.1 - 7.8e-12 45.1 0.1 1.6e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain TPR_10 PF13374.1 KEZ41458.1 - 2.7e-45 151.0 0.0 7.3e-13 47.9 0.0 4.7 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ41458.1 - 1.8e-44 149.5 0.4 1.3e-17 63.5 0.0 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ41458.1 - 3.5e-12 45.5 0.9 0.12 12.6 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ41458.1 - 1e-09 37.4 2.6 0.0013 18.4 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ41458.1 - 2.1e-07 30.6 0.0 0.67 10.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ41458.1 - 3.2e-07 29.7 0.1 0.25 11.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ41458.1 - 2.3e-06 27.1 0.3 0.26 10.9 0.0 3.8 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 KEZ41458.1 - 8.5e-06 25.1 4.2 0.17 11.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ41458.1 - 0.00026 20.5 0.1 0.85 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ41458.1 - 0.0016 18.7 0.2 3.6 8.0 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ41458.1 - 0.002 18.7 0.0 1.2 9.9 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ41458.1 - 0.0059 16.9 2.7 11 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 KEZ41458.1 - 0.0079 16.3 0.4 13 6.4 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 KEZ41458.1 - 0.0096 16.4 0.5 8.4 7.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 KEZ41458.1 - 0.053 13.5 0.0 7.9 6.7 0.0 2.8 2 0 0 2 2 2 0 PPR repeat DUF4074 PF13293.1 KEZ41458.1 - 0.078 13.2 0.0 29 4.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4074) Epimerase PF01370.16 KEZ41460.1 - 9.3e-15 54.7 0.0 1.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEZ41460.1 - 8.6e-14 51.1 0.0 1.7e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEZ41460.1 - 0.0002 20.3 0.0 0.00066 18.6 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KEZ41460.1 - 0.0011 17.7 0.1 0.0028 16.4 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEZ41460.1 - 0.0027 17.6 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Macro PF01661.16 KEZ41460.1 - 0.0072 16.2 0.1 0.049 13.5 0.0 2.4 3 1 0 3 3 3 1 Macro domain KR PF08659.5 KEZ41460.1 - 0.092 12.4 0.0 0.83 9.2 0.0 2.0 2 0 0 2 2 2 0 KR domain DnaJ-X PF14308.1 KEZ41461.1 - 1.6e-70 236.5 0.6 1.6e-70 236.5 0.4 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KEZ41461.1 - 1.6e-26 91.7 1.3 3.6e-26 90.6 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2884 PF11101.3 KEZ41461.1 - 0.04 13.3 2.3 0.078 12.3 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) SRA1 PF07304.6 KEZ41461.1 - 0.061 13.0 0.9 0.51 10.0 0.1 2.2 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) SQS_PSY PF00494.14 KEZ41462.1 - 2.5e-34 118.7 0.0 4.3e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_S8 PF00082.17 KEZ41463.1 - 2.3e-45 154.9 12.1 3.2e-45 154.4 8.4 1.2 1 0 0 1 1 1 1 Subtilase family Phage-tail_3 PF13550.1 KEZ41463.1 - 0.034 13.9 0.2 0.075 12.8 0.2 1.5 1 0 0 1 1 1 0 Putative phage tail protein F-box-like PF12937.2 KEZ41464.1 - 0.00039 20.0 0.0 0.0016 18.1 0.0 2.1 2 1 0 2 2 2 1 F-box-like PRANC PF09372.5 KEZ41464.1 - 0.16 11.9 0.0 29 4.7 0.0 2.5 2 0 0 2 2 2 0 PRANC domain Mannosyl_trans PF05007.8 KEZ41465.1 - 2.1e-75 253.7 11.2 2.9e-75 253.2 7.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KEZ41465.1 - 1.2e-13 50.7 1.0 1.2e-13 50.7 0.7 2.3 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KEZ41465.1 - 0.00017 21.1 22.2 0.00017 21.1 15.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) Translin PF01997.11 KEZ41466.1 - 2.3e-45 154.6 0.0 2.8e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Translin family adh_short PF00106.20 KEZ41467.1 - 1.5e-28 99.8 2.4 2.1e-28 99.3 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ41467.1 - 2.2e-14 53.8 0.0 2.8e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ41467.1 - 4.2e-14 52.6 0.8 6.3e-14 52.0 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ41467.1 - 0.00046 19.6 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.1 KEZ41467.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Eno-Rase_NADH_b PF12242.3 KEZ41467.1 - 0.043 13.6 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KEZ41467.1 - 0.18 10.6 0.0 0.34 9.7 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Grp1_Fun34_YaaH PF01184.14 KEZ41469.1 - 1e-82 276.5 13.7 1.3e-82 276.1 9.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 7TMR-DISM_7TM PF07695.6 KEZ41470.1 - 0.074 12.7 18.0 0.68 9.5 1.3 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF4018 PF13210.1 KEZ41470.1 - 0.48 9.7 8.8 0.77 9.1 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) PgaD PF13994.1 KEZ41470.1 - 0.78 9.2 6.0 7.4 6.0 2.7 2.3 2 0 0 2 2 2 0 PgaD-like protein UNC-50 PF05216.8 KEZ41470.1 - 0.88 8.7 9.0 1.6 7.8 6.2 1.6 1 1 0 1 1 1 0 UNC-50 family MARVEL PF01284.18 KEZ41470.1 - 2.2 8.0 20.0 3.1 7.6 13.9 1.2 1 0 0 1 1 1 0 Membrane-associating domain Herpes_LMP1 PF05297.6 KEZ41470.1 - 2.9 6.7 4.8 2.8 6.7 2.8 1.4 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4282 PF14110.1 KEZ41470.1 - 3.2 7.9 10.4 1.7 8.8 4.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) Myc_target_1 PF15179.1 KEZ41470.1 - 5.3 6.5 9.6 9.8 5.7 2.7 2.1 2 0 0 2 2 2 0 Myc target protein 1 p450 PF00067.17 KEZ41471.1 - 5e-55 186.8 0.0 6.2e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 KEZ41472.1 - 0.00018 21.6 0.0 0.0004 20.4 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 KEZ41472.1 - 0.0026 16.3 0.0 0.13 10.7 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Zn_clus PF00172.13 KEZ41473.1 - 0.013 15.3 2.2 0.039 13.8 1.5 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S15 PF02129.13 KEZ41474.1 - 5.7e-38 130.8 0.2 9.3e-33 113.7 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KEZ41474.1 - 2.4e-17 63.5 0.0 3.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Sugar_tr PF00083.19 KEZ41475.1 - 1.6e-83 280.7 27.2 1.9e-83 280.5 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41475.1 - 3.2e-30 105.0 39.9 2.3e-28 98.9 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1736 PF08409.6 KEZ41475.1 - 0.061 12.9 0.1 0.061 12.9 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1736) Pectate_lyase_3 PF12708.2 KEZ41476.1 - 4.6e-60 203.5 8.3 5.3e-52 177.1 1.1 3.2 2 2 0 2 2 2 2 Pectate lyase superfamily protein HRXXH PF13933.1 KEZ41477.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 KEZ41477.1 - 0.023 15.2 0.0 0.06 13.8 0.0 1.7 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase ABM PF03992.11 KEZ41478.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase adh_short PF00106.20 KEZ41479.1 - 7.2e-32 110.6 1.8 9.5e-32 110.2 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ41479.1 - 3.3e-21 76.1 0.0 4.1e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ41479.1 - 5.2e-13 49.0 0.9 7.9e-13 48.4 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ41479.1 - 0.02 14.3 0.1 0.038 13.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 KEZ41479.1 - 0.029 14.1 0.1 0.094 12.5 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain SnoaL_3 PF13474.1 KEZ41480.1 - 1.1e-08 35.1 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KEZ41480.1 - 0.0073 16.5 0.9 0.013 15.7 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Pyr_redox_3 PF13738.1 KEZ41481.1 - 6.8e-21 75.2 0.0 1.1e-20 74.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ41481.1 - 2.9e-11 42.2 0.0 4.2e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KEZ41481.1 - 3.6e-10 40.0 0.0 4.3e-07 30.0 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ41481.1 - 2.2e-08 33.4 0.0 3e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEZ41481.1 - 5.4e-08 32.7 0.0 6.1e-07 29.3 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEZ41481.1 - 0.00014 21.7 0.0 0.0099 15.6 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KEZ41481.1 - 0.0018 17.2 0.5 0.43 9.4 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ41481.1 - 0.0062 15.6 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 KEZ41481.1 - 0.0063 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain TetR PF13972.1 KEZ41481.1 - 0.011 15.2 0.1 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor 2-Hacid_dh_C PF02826.14 KEZ41481.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEZ41481.1 - 0.047 13.9 0.0 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KEZ41481.1 - 0.063 12.1 0.0 0.23 10.3 0.0 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEZ41481.1 - 0.17 10.8 0.0 0.45 9.4 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_6 PF12697.2 KEZ41482.1 - 4.8e-23 82.2 0.0 6.2e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ41482.1 - 2.9e-13 49.9 0.0 1.6e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ41482.1 - 4.7e-09 36.1 0.0 1.5e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KEZ41482.1 - 0.00087 19.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.11 KEZ41482.1 - 0.0094 15.4 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 KEZ41482.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain NMT_C PF02799.10 KEZ41483.1 - 2e-73 245.8 0.0 3e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KEZ41483.1 - 2e-69 232.3 0.1 4.6e-69 231.1 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KEZ41483.1 - 3.5e-07 30.1 0.4 0.00038 20.3 0.0 3.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEZ41483.1 - 0.031 14.4 0.1 0.083 13.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cnd1_N PF12922.2 KEZ41483.1 - 0.11 12.1 3.5 0.24 10.9 2.4 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term NST1 PF13945.1 KEZ41483.1 - 0.13 12.3 5.7 0.24 11.4 3.9 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Med3 PF11593.3 KEZ41483.1 - 0.16 11.1 3.0 0.22 10.6 2.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal eIF-3c_N PF05470.7 KEZ41483.1 - 0.93 7.4 8.2 1.4 6.9 5.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PGA2 PF07543.7 KEZ41483.1 - 1.6 8.5 9.1 3.2 7.5 6.3 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Abhydrolase_5 PF12695.2 KEZ41484.1 - 4.5e-16 58.9 0.0 1e-15 57.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ41484.1 - 1e-13 51.7 0.1 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ41484.1 - 6.3e-07 29.1 0.0 7.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KEZ41484.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEZ41484.1 - 0.0022 17.8 0.0 0.0059 16.4 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 KEZ41484.1 - 0.0028 16.2 0.0 0.004 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KEZ41484.1 - 0.041 13.0 0.0 0.11 11.6 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEZ41484.1 - 0.073 12.4 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 KEZ41484.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3349 PF11829.3 KEZ41485.1 - 0.072 13.5 0.4 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Bac_small_YrzI PF09501.5 KEZ41485.1 - 9.1 6.2 6.0 36 4.3 0.5 2.6 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) HIG_1_N PF04588.8 KEZ41486.1 - 1.1e-20 73.0 0.2 2e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region AAA_23 PF13476.1 KEZ41486.1 - 0.027 14.8 1.0 0.032 14.5 0.7 1.3 1 0 0 1 1 1 0 AAA domain OPA3 PF07047.7 KEZ41486.1 - 0.12 12.2 0.2 0.12 12.2 0.2 1.9 1 1 1 2 2 2 0 Optic atrophy 3 protein (OPA3) PALP PF00291.20 KEZ41487.1 - 1.2e-69 234.8 0.6 1.6e-69 234.4 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KEZ41487.1 - 8e-41 137.5 0.0 2e-21 75.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 KEZ41488.1 - 3.6e-21 74.8 14.3 6.9e-21 73.9 9.9 1.5 1 1 0 1 1 1 1 Ribosomal protein L36 Acetyltransf_1 PF00583.19 KEZ41489.1 - 7.7e-13 48.2 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ41489.1 - 2.7e-07 30.6 0.0 4.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEZ41489.1 - 8.2e-07 29.1 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEZ41489.1 - 8.9e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KEZ41489.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEZ41489.1 - 0.024 14.5 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEZ41489.1 - 0.056 13.6 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2156 PF09924.4 KEZ41489.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2156) MutS_V PF00488.16 KEZ41490.1 - 9e-81 270.7 0.0 2e-80 269.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEZ41490.1 - 1.2e-48 165.6 0.1 2.1e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KEZ41490.1 - 7.7e-33 112.9 0.0 4.9e-32 110.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 KEZ41490.1 - 5e-16 59.0 0.0 1.8e-15 57.2 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KEZ41490.1 - 5.3e-15 55.3 0.3 1.2e-14 54.2 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 KEZ41490.1 - 0.012 15.9 1.2 0.032 14.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEZ41490.1 - 0.013 15.0 0.1 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KEZ41490.1 - 0.28 11.0 1.4 0.38 10.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF3176 PF11374.3 KEZ41491.1 - 7.5e-24 83.7 2.4 2.8e-23 81.9 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Ku_C PF03730.9 KEZ41491.1 - 0.05 14.1 0.3 2.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm CTD PF12815.2 KEZ41491.1 - 0.19 12.1 13.4 2.8 8.3 9.3 2.3 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 HEAT_2 PF13646.1 KEZ41493.1 - 2.9e-50 168.4 46.5 1.1e-14 54.4 2.2 7.1 1 1 6 7 7 7 7 HEAT repeats HEAT PF02985.17 KEZ41493.1 - 5.7e-34 113.1 16.7 0.00082 19.2 0.0 12.1 12 0 0 12 12 12 8 HEAT repeat HEAT_EZ PF13513.1 KEZ41493.1 - 1.8e-28 98.2 44.5 0.0005 20.4 0.2 10.5 6 2 4 10 10 10 8 HEAT-like repeat NACHT PF05729.7 KEZ41493.1 - 2.6e-16 59.7 0.0 6.3e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Arm PF00514.18 KEZ41493.1 - 1.5e-12 46.8 31.9 0.065 13.0 0.0 10.4 8 3 3 11 11 11 4 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KEZ41493.1 - 2.1e-08 34.2 0.0 0.56 10.0 0.0 5.2 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 NB-ARC PF00931.17 KEZ41493.1 - 6.8e-08 31.7 0.0 1.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEZ41493.1 - 4.3e-07 30.1 0.0 2.2e-06 27.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain Adaptin_N PF01602.15 KEZ41493.1 - 2e-05 23.1 0.1 0.93 7.7 0.3 3.9 2 1 0 2 2 2 2 Adaptin N terminal region DUF484 PF04340.7 KEZ41493.1 - 0.00016 21.2 1.3 15 4.9 0.0 4.3 3 1 1 4 4 4 0 Protein of unknown function, DUF484 Vac14_Fab1_bd PF12755.2 KEZ41493.1 - 0.00028 21.2 0.0 48 4.4 0.0 6.0 3 3 2 6 6 6 0 Vacuolar 14 Fab1-binding region AAA_17 PF13207.1 KEZ41493.1 - 0.00044 21.0 0.0 0.0022 18.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEZ41493.1 - 0.0014 18.7 0.0 0.0047 17.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) CLASP_N PF12348.3 KEZ41493.1 - 0.0056 16.0 0.3 30 3.8 0.0 5.0 3 2 2 6 6 6 0 CLASP N terminal AAA_18 PF13238.1 KEZ41493.1 - 0.016 15.5 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF829 PF05705.9 KEZ41493.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) AAA_14 PF13173.1 KEZ41493.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4042 PF13251.1 KEZ41493.1 - 0.045 13.2 0.1 48 3.3 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function (DUF4042) DUF676 PF05057.9 KEZ41493.1 - 0.046 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NTPase_1 PF03266.10 KEZ41493.1 - 0.07 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 KEZ41493.1 - 0.2 11.3 0.1 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KEZ41493.1 - 0.27 11.4 0.0 0.61 10.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HEAT_PBS PF03130.11 KEZ41493.1 - 1.1 9.8 61.3 9 7.0 0.1 11.6 11 0 0 11 11 11 0 PBS lyase HEAT-like repeat Nipped-B_C PF12830.2 KEZ41493.1 - 3.9 7.0 4.2 95 2.5 0.0 4.8 6 2 1 7 7 6 0 Sister chromatid cohesion C-terminus DLH PF01738.13 KEZ41495.1 - 1.6e-31 109.3 0.0 1.9e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ41495.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ41495.1 - 0.00049 19.7 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ41495.1 - 0.00078 19.3 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KEZ41495.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_61 PF03443.9 KEZ41497.1 - 4.1e-47 160.8 0.5 4.8e-47 160.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldedh PF00171.17 KEZ41499.1 - 5.2e-141 470.1 3.5 6.1e-141 469.8 2.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ41499.1 - 0.003 16.3 0.0 0.0065 15.2 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Fungal_trans PF04082.13 KEZ41500.1 - 1.8e-08 33.6 0.4 3.1e-08 32.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41500.1 - 1.5e-06 27.9 10.2 3.2e-06 26.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_3 PF12776.2 KEZ41501.1 - 0.034 14.7 0.9 0.21 12.2 0.2 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain TFIIS_M PF07500.9 KEZ41502.1 - 3e-25 88.5 1.4 3e-25 88.5 0.9 1.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KEZ41502.1 - 8.9e-18 63.6 7.7 1.5e-17 62.9 5.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KEZ41502.1 - 2e-13 49.6 0.1 4.2e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.8 KEZ41502.1 - 0.028 14.0 4.3 0.079 12.6 3.0 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SPK PF04435.13 KEZ41502.1 - 0.13 12.2 0.8 15 5.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF545) ATP-synt_E PF05680.7 KEZ41502.1 - 5.5 7.0 9.2 0.24 11.3 1.1 2.6 2 2 1 3 3 3 0 ATP synthase E chain Methyltransf_28 PF02636.12 KEZ41503.1 - 1.3e-38 132.8 0.0 1.9e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KEZ41503.1 - 0.00036 19.5 0.0 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase RrnaAD PF00398.15 KEZ41503.1 - 0.01 14.8 0.0 0.053 12.5 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 KEZ41503.1 - 0.04 14.4 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_2c PF01411.14 KEZ41504.1 - 3.6e-209 695.6 0.0 3.6e-209 695.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KEZ41504.1 - 9.6e-16 57.4 0.1 2.2e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KEZ41504.1 - 0.017 14.7 0.4 0.067 12.8 0.3 2.1 1 0 0 1 1 1 0 DHHA1 domain TMEM247 PF15444.1 KEZ41506.1 - 0.038 13.7 0.2 0.038 13.7 0.2 1.5 2 0 0 2 2 2 0 Transmembrane protein 247 Mei5 PF10376.4 KEZ41506.1 - 0.37 10.2 18.1 0.94 8.9 0.3 3.4 1 1 1 2 2 2 0 Double-strand recombination repair protein Spc24 PF08286.6 KEZ41506.1 - 1.3 8.7 6.2 0.64 9.7 1.9 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 RCR PF12273.3 KEZ41507.1 - 3.2e-06 27.7 3.7 6.9e-06 26.6 2.5 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Glyco_transf_28 PF03033.15 KEZ41508.1 - 3.2e-20 72.2 0.0 1.6e-19 70.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KEZ41508.1 - 2.2e-05 23.1 0.0 3.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 KEZ41508.1 - 8.5e-05 22.6 0.0 0.00028 21.0 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 KEZ41508.1 - 0.00027 20.6 2.5 0.00083 19.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.15 KEZ41508.1 - 0.0013 18.0 37.6 0.015 14.7 0.4 8.3 8 0 0 8 8 8 5 Ubiquitin interaction motif Sec61_beta PF03911.11 KEZ41509.1 - 6.7e-21 73.8 1.5 9e-21 73.3 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family NIF PF03031.13 KEZ41510.1 - 1.2e-51 174.5 0.2 1.8e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KEZ41510.1 - 0.47 10.6 2.8 1.1 9.5 0.0 2.4 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase ABC_membrane_2 PF06472.10 KEZ41511.1 - 5e-97 324.4 1.7 1.2e-96 323.1 0.1 2.2 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEZ41511.1 - 2.6e-15 56.9 0.0 8.6e-15 55.2 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_17 PF13207.1 KEZ41511.1 - 0.0024 18.6 0.8 0.023 15.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 KEZ41511.1 - 0.0052 16.7 0.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ41511.1 - 0.022 14.7 0.4 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.16 KEZ41511.1 - 0.031 13.4 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEZ41511.1 - 0.034 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 KEZ41511.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KEZ41511.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 KEZ41511.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEZ41511.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KEZ41511.1 - 0.2 10.8 0.0 0.39 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KEZ41511.1 - 0.49 10.7 5.0 2.2 8.5 1.7 2.8 2 1 0 2 2 1 0 AAA domain Aldo_ket_red PF00248.16 KEZ41512.1 - 1.4e-50 171.7 0.0 1.5e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 KEZ41513.1 - 2.2e-42 142.0 34.6 7.1e-11 41.4 0.1 7.0 2 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ41513.1 - 1.1e-28 98.7 47.6 1.9e-07 30.7 3.0 5.2 1 1 7 8 8 8 8 Leucine rich repeat LRR_9 PF14580.1 KEZ41513.1 - 6.8e-13 48.5 10.7 6.4e-05 22.5 0.8 3.7 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 KEZ41513.1 - 3.4e-12 44.5 19.4 0.79 9.9 0.3 10.8 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 KEZ41513.1 - 6.7e-11 40.5 9.7 3.6 8.2 0.0 9.3 9 0 0 9 9 9 2 Leucine rich repeat LRR_6 PF13516.1 KEZ41513.1 - 1e-10 40.5 13.7 0.19 11.9 0.2 9.9 7 3 3 10 10 10 2 Leucine Rich repeat Sial-lect-inser PF09264.5 KEZ41513.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Vibrio cholerae sialidase, lectin insertion Abhydrolase_5 PF12695.2 KEZ41514.1 - 3e-08 33.5 0.0 4.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ41514.1 - 4.2e-07 30.0 0.0 9.2e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ41514.1 - 5.5e-05 22.8 0.0 0.00013 21.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ41514.1 - 0.0057 15.9 0.0 0.0082 15.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEZ41514.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SET PF00856.23 KEZ41516.1 - 9.4e-11 42.2 0.3 2.8e-10 40.7 0.0 2.0 2 1 0 2 2 2 1 SET domain Nop25 PF09805.4 KEZ41516.1 - 0.18 11.8 10.8 0.27 11.3 4.2 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) F-box-like PF12937.2 KEZ41517.1 - 0.0015 18.1 0.2 0.0042 16.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like Kinetochor_Ybp2 PF08568.5 KEZ41518.1 - 2.4e-109 366.4 0.0 3.2e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Endonuclease_5 PF04493.9 KEZ41518.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Endonuclease V MaoC_dehydratas PF01575.14 KEZ41519.1 - 0.00023 20.5 0.0 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain eRF1_2 PF03464.10 KEZ41520.1 - 7.6e-47 158.9 0.1 1.4e-46 158.0 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KEZ41520.1 - 6.4e-39 132.7 0.6 1.5e-38 131.5 0.4 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KEZ41520.1 - 1.5e-28 98.9 0.0 3.1e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 DUF1770 PF08589.5 KEZ41521.1 - 9.5e-19 67.8 2.3 4.7e-18 65.6 1.6 1.9 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Plasmid_stabil PF05016.9 KEZ41522.1 - 0.032 14.6 0.4 0.076 13.4 0.3 1.6 1 0 0 1 1 1 0 Plasmid stabilisation system protein Pertussis_S1 PF02917.9 KEZ41522.1 - 0.051 13.1 0.3 0.078 12.5 0.2 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 WHIM1 PF15612.1 KEZ41522.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.7 KEZ41522.1 - 3.2 5.5 12.9 4.7 5.0 8.9 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L2_C PF03947.13 KEZ41523.1 - 8.1e-39 132.3 4.3 1.4e-38 131.6 3.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KEZ41523.1 - 1.8e-16 59.8 0.1 3.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 KEZ41524.1 - 1.8e-63 214.4 0.1 2.2e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KEZ41524.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 KEZ41525.1 - 3.8e-33 114.9 0.8 5.8e-33 114.2 0.5 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KEZ41525.1 - 5.7e-17 61.9 0.2 2e-16 60.1 0.1 2.0 1 0 0 1 1 1 1 Telomerase activating protein Est1 zf-C2H2_4 PF13894.1 KEZ41526.1 - 0.53 10.7 14.9 2.4 8.7 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ41526.1 - 3.7 8.0 15.5 0.51 10.7 1.2 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type G10 PF01125.12 KEZ41527.1 - 6.6e-40 136.0 0.1 7.3e-40 135.8 0.1 1.0 1 0 0 1 1 1 1 G10 protein DUF1040 PF06288.8 KEZ41527.1 - 0.044 14.0 0.1 0.089 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) Complex1_LYR PF05347.10 KEZ41528.1 - 4.4e-07 29.5 0.3 7.4e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KEZ41528.1 - 2.4e-06 27.9 0.1 3e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KEZ41528.1 - 5e-06 26.6 0.2 9.3e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Complex1_LYR-like RNA_pol_L_2 PF13656.1 KEZ41529.1 - 2.3e-30 103.8 0.0 3.3e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KEZ41529.1 - 1.7e-09 36.6 0.0 2.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 KEZ41531.1 - 5e-64 215.9 0.0 7.6e-64 215.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41531.1 - 6.3e-28 97.5 0.0 8.7e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ41531.1 - 0.0026 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ41531.1 - 0.03 14.0 0.4 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ41531.1 - 0.03 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KEZ41531.1 - 0.04 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 KEZ41531.1 - 6.8 6.4 6.0 8.4 6.1 4.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 KEZ41532.1 - 9.6e-59 198.6 0.0 2.4e-58 197.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41532.1 - 5.7e-34 117.3 0.0 1.2e-31 109.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEZ41532.1 - 1e-07 31.2 0.0 6.8e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEZ41532.1 - 0.00015 21.6 0.0 0.00037 20.2 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEZ41532.1 - 0.051 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sybindin PF04099.7 KEZ41533.1 - 1.2e-25 89.8 0.0 1.5e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KEZ41533.1 - 0.056 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Peroxin-3 PF04882.7 KEZ41534.1 - 1.6e-142 475.2 0.1 1.9e-142 475.0 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF4124 PF13511.1 KEZ41534.1 - 1.7 8.7 7.2 0.19 11.8 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) DUF1649 PF07855.7 KEZ41535.1 - 5.7e-57 191.9 0.0 7.1e-57 191.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Sugarporin_N PF11471.3 KEZ41535.1 - 0.019 14.5 0.3 0.041 13.5 0.2 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension YlbD_coat PF14071.1 KEZ41535.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative coat protein EF-hand_4 PF12763.2 KEZ41536.1 - 5.6e-28 96.7 0.0 2.5e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KEZ41536.1 - 0.00018 20.5 0.0 0.34 10.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KEZ41536.1 - 0.00043 20.3 0.3 0.53 10.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KEZ41536.1 - 0.0011 18.6 0.1 1.3 9.0 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain DUF1720 PF08226.6 KEZ41536.1 - 0.003 17.5 26.1 0.003 17.5 18.1 7.8 5 2 3 8 8 8 2 Domain of unknown function (DUF1720) EF-hand_8 PF13833.1 KEZ41536.1 - 0.0081 15.7 0.0 1 9.0 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair NAD_binding_1 PF00175.16 KEZ41537.1 - 6.4e-28 97.4 0.0 9.5e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEZ41537.1 - 2e-26 92.0 0.0 3.1e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEZ41537.1 - 6.1e-05 22.9 0.0 0.0088 15.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain mRNA_cap_enzyme PF01331.14 KEZ41538.1 - 5e-51 173.1 0.7 6.8e-51 172.7 0.5 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KEZ41538.1 - 1e-17 64.3 0.0 2.4e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KEZ41538.1 - 4.9e-07 29.3 0.2 7.3e-05 22.2 0.1 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain TPR_2 PF07719.12 KEZ41539.1 - 2.6e-32 108.1 34.4 7.7e-05 22.3 0.3 13.9 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ41539.1 - 3.3e-30 103.5 37.2 5.4e-08 32.3 0.4 12.0 9 5 5 14 14 14 7 TPR repeat TPR_1 PF00515.23 KEZ41539.1 - 3e-27 93.0 33.8 1.4e-05 24.4 0.2 12.7 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ41539.1 - 1.5e-22 77.6 22.4 0.00019 20.9 0.0 13.2 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ41539.1 - 9.9e-20 70.2 49.8 1.5e-07 31.2 0.6 12.4 10 4 0 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ41539.1 - 5.4e-19 66.9 27.6 1.3e-05 25.4 0.1 13.2 10 3 3 13 13 12 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ41539.1 - 6.8e-19 67.9 29.6 1.1e-05 25.7 0.2 11.5 8 1 3 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ41539.1 - 6.3e-18 63.0 27.4 0.00011 21.6 0.1 11.2 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ41539.1 - 1.2e-15 57.6 37.8 0.0025 18.4 0.0 11.1 8 3 4 12 12 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ41539.1 - 1.4e-11 43.6 12.4 0.92 9.8 0.2 10.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ41539.1 - 4.3e-11 42.5 29.2 4.3e-05 23.6 0.0 9.9 11 0 0 11 11 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KEZ41539.1 - 5.4e-08 32.8 21.5 0.0099 15.9 0.9 7.3 6 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEZ41539.1 - 5.1e-06 26.2 28.6 0.1 12.5 0.1 9.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_3 PF07720.7 KEZ41539.1 - 0.00038 20.1 5.7 1.1 9.0 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR PF01535.15 KEZ41539.1 - 0.018 14.9 0.8 1.5 8.9 0.0 3.8 3 0 0 3 3 2 0 PPR repeat Ank_2 PF12796.2 KEZ41540.1 - 9.8e-56 186.0 1.7 2.9e-14 53.1 0.0 5.4 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41540.1 - 7.2e-51 167.5 5.5 2.8e-08 33.1 0.4 10.9 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 KEZ41540.1 - 1e-37 127.3 6.0 3.5e-09 36.6 0.0 7.6 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ41540.1 - 1.9e-32 108.0 3.5 0.00026 20.9 0.2 9.6 11 0 0 11 11 9 6 Ankyrin repeat Ank_4 PF13637.1 KEZ41540.1 - 3.3e-32 110.2 4.7 2.1e-08 34.4 0.2 7.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Patatin PF01734.17 KEZ41540.1 - 2.1e-28 99.6 0.0 4e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_16 PF13191.1 KEZ41540.1 - 5.6e-09 36.2 1.3 2.7e-08 34.0 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KEZ41540.1 - 1e-08 35.0 0.0 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 KEZ41540.1 - 0.0018 17.3 0.0 0.26 10.2 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain AAA PF00004.24 KEZ41540.1 - 0.0072 16.5 0.0 0.029 14.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KEZ41540.1 - 0.0092 14.8 0.0 0.024 13.5 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 KEZ41540.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 KEZ41540.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KEZ41540.1 - 0.018 15.1 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ41540.1 - 0.024 14.3 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain DUF2075 PF09848.4 KEZ41540.1 - 0.036 13.0 0.0 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KEZ41540.1 - 0.06 13.6 0.0 0.24 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEZ41540.1 - 0.061 14.1 0.0 0.4 11.5 0.0 2.5 2 0 0 2 2 1 0 AAA domain Nab2 PF11517.3 KEZ41540.1 - 0.1 12.7 0.0 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) AAA_14 PF13173.1 KEZ41540.1 - 0.11 12.3 0.0 0.55 10.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.5 KEZ41540.1 - 0.18 10.9 0.0 0.44 9.7 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 PX PF00787.19 KEZ41541.1 - 1.8e-18 66.3 0.0 6.7e-18 64.5 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KEZ41541.1 - 1.6e-15 57.0 12.5 2.2e-10 40.1 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Spore_GerAC PF05504.6 KEZ41541.1 - 0.12 12.1 1.6 22 4.8 1.7 2.3 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal RNA_polI_A14 PF08203.6 KEZ41541.1 - 0.19 11.9 2.4 0.57 10.4 0.4 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 HEAT_2 PF13646.1 KEZ41543.1 - 3.6e-06 27.1 0.5 9.5e-05 22.6 0.1 3.7 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KEZ41543.1 - 0.0003 20.6 3.4 0.48 10.6 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KEZ41543.1 - 0.0014 19.0 5.5 0.012 16.1 0.1 4.5 3 0 0 3 3 3 1 HEAT-like repeat SNF5 PF04855.7 KEZ41544.1 - 4.6e-76 255.4 0.7 4.6e-76 255.4 0.5 1.5 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 TolB_N PF04052.8 KEZ41544.1 - 0.15 12.1 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 TolB amino-terminal domain Peptidase_M24 PF00557.19 KEZ41545.1 - 2.5e-11 43.5 0.1 5.3e-11 42.4 0.1 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 BLVR PF06375.6 KEZ41545.1 - 0.051 13.3 6.0 0.1 12.4 4.2 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) PHD PF00628.24 KEZ41546.1 - 6.5e-15 54.5 23.3 1.3e-08 34.4 7.6 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 KEZ41546.1 - 0.00039 20.0 17.5 0.0016 18.1 1.4 2.5 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 KEZ41546.1 - 0.057 13.1 12.1 0.18 11.5 2.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KEZ41546.1 - 0.94 8.8 11.5 0.21 10.9 3.0 2.6 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 KEZ41546.1 - 1.7 7.9 12.0 2.4 7.4 2.6 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DZR PF12773.2 KEZ41546.1 - 4.8 7.0 13.6 1.1 9.1 0.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon Synaptobrevin PF00957.16 KEZ41547.1 - 5.9e-14 51.4 0.6 1e-13 50.6 0.4 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEZ41547.1 - 4.6e-12 45.3 0.0 9e-12 44.3 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain PUF PF00806.14 KEZ41548.1 - 2.5e-24 83.3 0.0 2.8e-05 23.3 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 KEZ41548.1 - 3e-13 49.2 0.0 5.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41548.1 - 1.9e-08 33.9 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41548.1 - 1.8e-06 27.8 0.0 5.2e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 KEZ41549.1 - 6.9e-35 120.6 0.0 1.1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KEZ41549.1 - 8.7e-19 67.0 0.0 3.1e-18 65.2 0.0 2.0 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 FliG_C PF01706.11 KEZ41549.1 - 1.3 9.0 4.5 4.5 7.3 0.4 2.4 2 0 0 2 2 2 0 FliG C-terminal domain TPR_11 PF13414.1 KEZ41550.1 - 1.1e-34 117.9 25.0 2.1e-11 43.2 2.9 7.4 3 1 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 KEZ41550.1 - 1.1e-30 103.9 18.0 6.9e-06 25.4 0.0 8.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ41550.1 - 9.1e-30 100.1 31.5 2.5e-05 23.8 0.1 10.8 11 1 1 12 12 12 7 Tetratricopeptide repeat Apc3 PF12895.2 KEZ41550.1 - 3.2e-27 94.4 15.9 2e-22 79.1 0.2 3.7 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KEZ41550.1 - 5.7e-20 71.4 17.3 9.1e-05 22.7 0.3 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ41550.1 - 1.3e-19 70.3 30.0 1.1e-09 38.7 1.2 7.9 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ41550.1 - 6.2e-19 66.2 1.1 0.00029 20.4 0.2 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ41550.1 - 3.7e-18 65.2 26.3 5.4e-06 26.2 2.3 7.6 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ41550.1 - 1.5e-17 62.5 24.5 0.053 14.1 0.0 10.4 4 2 6 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ41550.1 - 1.2e-15 56.2 11.1 0.035 14.2 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ41550.1 - 1.8e-13 49.2 14.7 0.001 18.6 0.0 8.8 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ41550.1 - 1.8e-10 40.5 15.9 0.054 13.3 1.1 6.2 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ41550.1 - 9.8e-06 25.7 11.9 15 6.3 0.4 9.0 8 1 1 9 9 9 0 Tetratricopeptide repeat NTP_transf_4 PF13562.1 KEZ41550.1 - 0.0042 16.7 0.0 0.0095 15.5 0.0 1.6 1 0 0 1 1 1 1 Sugar nucleotidyl transferase TPR_4 PF07721.9 KEZ41550.1 - 0.0046 17.2 7.9 3.8 8.2 0.1 6.2 7 0 0 7 7 5 1 Tetratricopeptide repeat MIT PF04212.13 KEZ41550.1 - 0.023 14.5 1.5 0.41 10.5 0.1 3.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain FAT PF02259.18 KEZ41550.1 - 0.028 13.4 1.7 0.13 11.2 1.2 2.0 1 1 0 1 1 1 0 FAT domain Fis1_TPR_C PF14853.1 KEZ41550.1 - 0.3 10.9 12.3 2 8.3 0.0 5.4 7 0 0 7 7 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 KEZ41550.1 - 8 6.5 15.8 0.19 11.6 0.8 5.1 6 1 1 7 7 5 0 Tetratricopeptide repeat Histone PF00125.19 KEZ41551.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KEZ41551.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KEZ41551.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEZ41551.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KEZ41551.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KEZ41551.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sedlin_N PF04628.8 KEZ41552.1 - 1.5e-40 138.1 0.0 1.8e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 KEZ41552.1 - 0.00012 21.7 0.0 0.01 15.5 0.0 2.2 2 0 0 2 2 2 2 Sybindin-like family Peptidase_C25 PF01364.13 KEZ41552.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 DUF2509 PF10713.4 KEZ41552.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) L31 PF09784.4 KEZ41553.1 - 4.7e-47 158.2 1.0 5.3e-47 158.1 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 RRM_1 PF00076.17 KEZ41554.1 - 3e-16 58.8 0.0 4.3e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41554.1 - 1.5e-11 44.1 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41554.1 - 2.1e-08 33.8 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KEZ41555.1 - 0.0052 16.6 2.3 0.0068 16.2 0.2 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat AATF-Che1 PF13339.1 KEZ41555.1 - 0.25 11.4 2.4 17 5.5 2.7 2.4 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor EBP PF05241.7 KEZ41557.1 - 4.2e-60 202.1 7.7 4.2e-60 202.1 5.3 1.4 2 0 0 2 2 2 1 Emopamil binding protein GAT PF03127.9 KEZ41557.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 GAT domain NPV_P10 PF05531.7 KEZ41557.1 - 0.22 11.7 0.5 16 5.8 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KEZ41557.1 - 2.3 7.7 5.5 0.97 8.9 0.4 2.4 2 1 1 3 3 3 0 IncA protein DSS1_SEM1 PF05160.8 KEZ41558.1 - 0.042 13.6 2.1 0.097 12.4 1.5 1.5 1 0 0 1 1 1 0 DSS1/SEM1 family F-box PF00646.28 KEZ41558.1 - 0.14 11.8 0.2 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 F-box domain 2OG-FeII_Oxy_3 PF13640.1 KEZ41559.1 - 0.017 15.6 0.1 0.073 13.5 0.1 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEZ41559.1 - 0.039 14.2 0.0 0.67 10.2 0.0 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PUF PF00806.14 KEZ41560.1 - 3.8e-64 208.7 8.7 3.1e-08 32.6 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.12 KEZ41560.1 - 0.05 13.6 1.7 4.7 7.3 0.1 3.3 3 0 0 3 3 3 0 Saposin-like type B, region 2 DUF1640 PF07798.6 KEZ41561.1 - 1.2e-11 44.9 0.7 1.9e-11 44.3 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1191 PF06697.7 KEZ41561.1 - 0.025 13.3 0.2 0.038 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) BOF PF04076.8 KEZ41561.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein LsmAD PF06741.8 KEZ41561.1 - 2 8.5 6.3 2.5 8.2 0.0 2.9 3 0 0 3 3 3 0 LsmAD domain Nnf1 PF03980.9 KEZ41562.1 - 4e-25 87.9 0.5 1.2e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Nnf1 DUF3376 PF11856.3 KEZ41562.1 - 0.0022 17.4 1.2 0.0026 17.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) GOLGA2L5 PF15070.1 KEZ41562.1 - 0.0048 15.4 1.6 0.0059 15.1 1.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 LOH1CR12 PF10158.4 KEZ41562.1 - 0.014 15.2 0.5 0.061 13.1 0.2 1.9 1 1 1 2 2 2 0 Tumour suppressor protein YqjK PF13997.1 KEZ41562.1 - 0.014 15.5 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 YqjK-like protein TPR_MLP1_2 PF07926.7 KEZ41562.1 - 0.027 14.2 1.7 0.044 13.5 1.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein COG5 PF10392.4 KEZ41562.1 - 0.048 13.6 1.2 0.079 12.9 0.3 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 CCDC144C PF14915.1 KEZ41562.1 - 0.055 12.3 2.5 0.09 11.6 1.6 1.4 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.4 KEZ41562.1 - 0.081 12.7 1.4 0.18 11.6 0.9 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 KEZ41562.1 - 0.1 12.7 7.2 0.049 13.7 2.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) HALZ PF02183.13 KEZ41562.1 - 0.1 12.2 0.2 0.91 9.2 0.2 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 KEZ41562.1 - 0.14 10.7 3.3 0.21 10.2 1.2 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.9 KEZ41562.1 - 0.16 11.9 2.3 0.27 11.1 1.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF641 PF04859.7 KEZ41562.1 - 0.21 11.3 2.1 0.31 10.8 0.8 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) bZIP_1 PF00170.16 KEZ41562.1 - 0.37 10.7 3.5 5.6 7.0 0.0 2.8 2 1 1 3 3 3 0 bZIP transcription factor DivIC PF04977.10 KEZ41562.1 - 2.7 7.5 5.7 15 5.1 4.0 2.0 1 1 0 1 1 1 0 Septum formation initiator PH PF00169.24 KEZ41563.1 - 6.8e-07 29.4 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KEZ41563.1 - 4.8e-06 26.7 0.0 8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain NTF2 PF02136.15 KEZ41564.1 - 1.7e-24 86.4 0.0 2.5e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KEZ41564.1 - 8.8e-09 34.8 0.1 1.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41564.1 - 5.8e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41564.1 - 1.7e-06 27.7 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEZ41564.1 - 0.0043 16.8 1.5 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Asp-B-Hydro_N PF05279.6 KEZ41564.1 - 1.2 8.9 19.7 2.7 7.7 13.7 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CH PF00307.26 KEZ41565.1 - 8.1e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Zn_clus PF00172.13 KEZ41566.1 - 6.9e-05 22.6 13.6 0.00016 21.4 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4179 PF13786.1 KEZ41566.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Barstar PF01337.13 KEZ41566.1 - 0.11 12.4 0.1 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Barstar (barnase inhibitor) zf-C2H2_4 PF13894.1 KEZ41567.1 - 8.7e-06 25.7 5.9 0.0019 18.3 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ41567.1 - 0.015 15.5 4.6 0.17 12.3 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type L51_S25_CI-B8 PF05047.11 KEZ41569.1 - 7e-15 54.5 0.0 1.2e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.13 KEZ41570.1 - 2.2e-87 292.2 0.0 2.4e-87 292.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase U1snRNP70_N PF12220.3 KEZ41571.1 - 9.8e-31 105.9 3.6 1.9e-30 105.0 2.5 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KEZ41571.1 - 5.6e-18 64.3 0.0 3.6e-17 61.7 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41571.1 - 2.1e-12 46.8 0.0 3.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41571.1 - 6.7e-10 38.6 0.0 1.7e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 KEZ41572.1 - 6.3e-18 64.5 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Zn_clus PF00172.13 KEZ41572.1 - 1.4e-09 37.6 6.9 2.9e-09 36.6 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ41572.1 - 2.2e-09 36.5 0.0 4.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MAPEG PF01124.13 KEZ41573.1 - 9e-14 51.1 1.2 1.1e-13 50.8 0.8 1.1 1 0 0 1 1 1 1 MAPEG family Polysacc_lyase PF14099.1 KEZ41574.1 - 0.043 13.4 4.7 0.068 12.8 3.3 1.3 1 0 0 1 1 1 0 Polysaccharide lyase Na_H_Exchanger PF00999.16 KEZ41575.1 - 1.1e-67 228.1 42.3 1.4e-67 227.9 29.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HSA PF07529.8 KEZ41576.1 - 4.2e-19 68.0 0.9 4.2e-19 68.0 0.7 3.7 4 1 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 KEZ41576.1 - 5.6e-12 45.5 0.8 5.6e-12 45.5 0.6 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEZ41576.1 - 0.00087 19.2 0.4 0.0025 17.8 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cytochrom_B561 PF03188.11 KEZ41577.1 - 3.7e-05 23.5 4.8 3.7e-05 23.5 3.3 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 AA_permease_C PF13906.1 KEZ41577.1 - 0.32 10.8 5.4 0.044 13.6 0.8 1.8 2 0 0 2 2 2 0 C-terminus of AA_permease NDUFA12 PF05071.11 KEZ41578.1 - 4.8e-13 49.4 0.3 4.8e-13 49.4 0.2 2.3 3 0 0 3 3 3 1 NADH ubiquinone oxidoreductase subunit NDUFA12 AMP-binding PF00501.23 KEZ41580.1 - 1.6e-14 53.1 0.0 1.5e-09 36.7 0.0 2.4 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ41580.1 - 2e-05 25.4 0.0 3.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1446 PF07287.6 KEZ41581.1 - 1.5e-120 401.9 0.0 2e-120 401.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Fungal_trans PF04082.13 KEZ41581.1 - 2e-13 49.8 0.4 3.2e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CoA_transf_3 PF02515.12 KEZ41582.1 - 4.2e-64 215.3 0.1 7e-64 214.5 0.1 1.4 1 0 0 1 1 1 1 CoA-transferase family III Fungal_trans PF04082.13 KEZ41583.1 - 9.9e-32 109.8 0.2 1.6e-31 109.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41583.1 - 1e-06 28.5 9.5 2.3e-06 27.4 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMGL-like PF00682.14 KEZ41584.1 - 2.7e-38 131.9 0.0 4.1e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 KEZ41584.1 - 2.4e-36 125.0 0.0 3.6e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 KEZ41585.1 - 1.2e-31 109.7 30.8 2.1e-30 105.6 22.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.17 KEZ41586.1 - 1.7e-151 504.7 0.0 1.9e-151 504.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEZ41586.1 - 0.093 11.9 0.0 4.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ADH_N PF08240.7 KEZ41587.1 - 5.9e-30 103.2 2.1 1.2e-29 102.2 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ41587.1 - 6.6e-17 61.2 0.2 1.3e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ41587.1 - 0.00021 22.1 0.0 0.00054 20.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KEZ41587.1 - 0.0012 18.4 0.2 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 KEZ41587.1 - 0.053 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ADH_N_assoc PF13823.1 KEZ41587.1 - 0.07 12.8 0.2 0.07 12.8 0.2 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Isochorismatase PF00857.15 KEZ41588.1 - 8.6e-09 35.5 0.0 1.6e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Hemerythrin PF01814.18 KEZ41589.1 - 4.6e-10 39.7 5.6 7.5e-10 39.0 3.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Photo_RC PF00124.14 KEZ41589.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre protein eIF-3c_N PF05470.7 KEZ41590.1 - 2.2e-174 580.8 17.3 2.2e-174 580.8 12.0 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KEZ41590.1 - 8.9e-13 48.4 1.7 2.3e-12 47.1 0.0 2.7 4 0 0 4 4 4 1 PCI domain DUF3713 PF12506.3 KEZ41590.1 - 0.063 13.3 2.4 0.18 11.9 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) Daxx PF03344.10 KEZ41590.1 - 0.36 9.2 26.1 0.58 8.5 18.1 1.3 1 0 0 1 1 1 0 Daxx Family Fe-S_biosyn PF01521.15 KEZ41591.1 - 4.9e-11 42.5 0.0 2.3e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 KEZ41592.1 - 2.7e-21 75.3 19.7 5e-21 74.5 13.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KEZ41592.1 - 6.3e-19 67.3 2.2 1e-18 66.6 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.6 KEZ41592.1 - 0.3 11.2 2.0 0.6 10.2 1.4 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus Ribosomal_S11 PF00411.14 KEZ41593.1 - 1.2e-40 138.0 0.6 1.5e-40 137.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 KEZ41593.1 - 0.047 12.5 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) SNF2_N PF00176.18 KEZ41594.1 - 4.7e-71 239.0 0.0 7.1e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ41594.1 - 3.6e-13 49.1 0.0 1.1e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ41594.1 - 8.1e-06 25.4 0.0 3.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KEZ41594.1 - 2.1e-05 23.4 0.0 6.4e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KEZ41594.1 - 0.00022 21.1 0.1 0.0012 18.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-bind_6 PF13921.1 KEZ41595.1 - 2.6e-14 53.0 0.1 2e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEZ41595.1 - 6.2e-12 45.3 0.2 0.00011 22.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain MEF2_binding PF09047.5 KEZ41595.1 - 0.27 10.9 1.4 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 MEF2 binding RNA_pol_I_A49 PF06870.7 KEZ41596.1 - 4.2e-59 200.0 0.2 5.1e-59 199.7 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Myelin_MBP PF01669.12 KEZ41596.1 - 0.074 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Myelin basic protein Pkinase PF00069.20 KEZ41597.1 - 7.9e-09 35.0 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KEZ41597.1 - 0.00022 20.3 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEZ41597.1 - 0.0046 16.7 0.7 0.51 10.0 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KEZ41597.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ECH PF00378.15 KEZ41598.1 - 1.1e-24 86.9 0.0 1.4e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family adh_short PF00106.20 KEZ41599.1 - 6.7e-23 81.4 0.1 1.2e-22 80.5 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ41599.1 - 1.1e-11 44.7 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ41599.1 - 4.2e-09 36.5 0.0 5.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ41599.1 - 0.0023 17.9 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KEZ41599.1 - 0.014 15.2 0.1 0.043 13.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Urb2 PF10441.4 KEZ41600.1 - 1.1e-49 169.0 0.0 5.6e-49 166.7 0.0 2.3 3 0 0 3 3 3 1 Urb2/Npa2 family FANCI_S3 PF14677.1 KEZ41600.1 - 0.029 13.7 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 FANCI solenoid 3 DUF543 PF04418.7 KEZ41601.1 - 6.4e-29 99.7 0.0 6.9e-29 99.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Pkinase PF00069.20 KEZ41602.1 - 5.4e-53 179.7 0.0 7.5e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41602.1 - 3.3e-25 88.6 0.0 5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEZ41602.1 - 3.4e-06 26.2 0.0 9.6e-06 24.7 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.21 KEZ41602.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain APH PF01636.18 KEZ41602.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3543 PF12063.3 KEZ41603.1 - 3.3e-89 298.1 0.1 5.3e-89 297.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KEZ41603.1 - 7.8e-60 202.1 0.0 1.4e-59 201.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41603.1 - 1.4e-41 142.3 0.0 2.5e-41 141.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase GCIP PF13324.1 KEZ41603.1 - 0.07 12.3 0.3 0.13 11.4 0.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Pox_ser-thr_kin PF05445.6 KEZ41603.1 - 0.077 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aminotran_3 PF00202.16 KEZ41604.1 - 2.1e-106 355.6 0.0 2.6e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KEZ41604.1 - 0.00018 20.7 0.0 0.00031 20.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KEZ41604.1 - 0.00039 19.4 0.0 0.00059 18.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_22 PF03901.12 KEZ41605.1 - 2.1e-71 241.1 15.9 2.8e-71 240.7 11.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 KEZ41605.1 - 4e-05 23.5 4.3 0.00089 19.1 3.0 2.8 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RhoGAP PF00620.22 KEZ41606.1 - 1.7e-37 128.3 0.0 2.9e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 KEZ41606.1 - 0.2 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family Nup188 PF10487.4 KEZ41607.1 - 2.4e-25 88.7 0.0 4.2e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.10 KEZ41608.1 - 1e-19 69.5 4.3 1.4e-19 69.1 3.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 KEZ41608.1 - 0.018 14.5 4.7 0.033 13.6 2.8 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) IGPS PF00218.16 KEZ41609.1 - 5.9e-97 323.7 0.2 1.1e-96 322.7 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KEZ41609.1 - 1.9e-52 177.7 0.3 2.1e-49 167.7 0.1 2.6 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KEZ41609.1 - 3.4e-50 170.1 0.1 3.3e-49 166.9 0.0 2.4 3 0 0 3 3 3 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEZ41609.1 - 0.00021 20.8 0.1 0.00076 18.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.16 KEZ41609.1 - 0.018 14.3 0.7 0.49 9.6 0.0 3.0 4 0 0 4 4 4 0 Histidine biosynthesis protein QRPTase_C PF01729.14 KEZ41609.1 - 0.037 13.5 2.6 1.3 8.5 0.1 3.4 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.13 KEZ41609.1 - 0.041 12.7 0.3 0.8 8.4 0.0 2.4 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PTCB-BRCT PF12738.2 KEZ41610.1 - 4.3e-06 26.4 0.0 9.2e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KEZ41610.1 - 3.8e-05 23.7 0.0 9.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAT PF03417.11 KEZ41610.1 - 0.032 13.6 0.1 0.071 12.5 0.1 1.5 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Use1 PF09753.4 KEZ41611.1 - 1.8e-06 27.5 0.5 8.9e-06 25.3 0.3 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF605 PF04652.11 KEZ41611.1 - 0.0011 18.4 13.3 0.0013 18.2 9.2 1.1 1 0 0 1 1 1 1 Vta1 like XRCC4 PF06632.7 KEZ41611.1 - 0.042 12.6 2.9 0.064 12.1 2.0 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 cwf21 PF08312.7 KEZ41612.1 - 1.9e-16 59.5 15.4 1.9e-16 59.5 10.7 1.9 2 0 0 2 2 2 1 cwf21 domain DUF1129 PF06570.6 KEZ41612.1 - 0.046 13.0 0.4 0.058 12.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) VIT1 PF01988.14 KEZ41612.1 - 0.45 9.9 1.5 0.57 9.6 1.0 1.2 1 0 0 1 1 1 0 VIT family TEX19 PF15553.1 KEZ41612.1 - 0.86 9.4 3.4 1.4 8.7 2.0 1.6 1 1 0 1 1 1 0 Testis-expressed protein 19 D123 PF07065.9 KEZ41613.1 - 4.5e-85 285.3 0.0 6.5e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 D123 BDV_P40 PF06407.6 KEZ41614.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.0 1 0 0 1 1 1 0 Borna disease virus P40 protein DUF3716 PF12511.3 KEZ41615.1 - 1.5e-15 56.5 10.3 2.4e-15 55.8 7.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) G-alpha PF00503.15 KEZ41616.1 - 3.5e-134 447.3 2.8 4.2e-134 447.0 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KEZ41616.1 - 2.7e-15 56.0 2.2 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 KEZ41616.1 - 0.00014 21.3 0.0 0.0006 19.3 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 KEZ41616.1 - 0.0016 18.9 0.9 3.1 8.3 0.1 3.0 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KEZ41616.1 - 0.0075 15.4 3.8 0.18 10.9 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KEZ41616.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KEZ41616.1 - 0.02 14.2 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KEZ41616.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 KEZ41616.1 - 0.11 12.5 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mog1 PF04603.7 KEZ41616.1 - 0.11 12.3 0.1 1 9.2 0.0 2.2 2 0 0 2 2 2 0 Ran-interacting Mog1 protein DUF1771 PF08590.5 KEZ41617.1 - 2.6e-23 81.7 8.6 4.6e-23 80.9 6.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KEZ41617.1 - 8.3e-16 57.9 0.4 2e-15 56.6 0.2 1.7 1 0 0 1 1 1 1 Smr domain KTI12 PF08433.5 KEZ41618.1 - 6.3e-65 219.0 0.0 9.7e-65 218.4 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEZ41618.1 - 3.3e-05 24.6 0.1 5.9e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ41618.1 - 0.0004 20.2 0.3 0.00084 19.2 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEZ41618.1 - 0.0023 18.2 0.0 0.008 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEZ41618.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 KEZ41618.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase STAT6_C PF14596.1 KEZ41618.1 - 0.2 11.6 0.2 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 STAT6 C-terminal AAA PF00004.24 KEZ41619.1 - 1.2e-98 326.4 0.0 8.3e-48 161.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KEZ41619.1 - 4.7e-20 71.3 1.0 1.4e-19 69.8 0.3 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 KEZ41619.1 - 6.3e-14 52.2 0.0 2.6e-07 30.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KEZ41619.1 - 9.8e-14 50.9 0.0 6.7e-06 25.3 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KEZ41619.1 - 4.5e-13 49.1 0.4 9.4e-07 28.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEZ41619.1 - 6.6e-13 48.7 0.0 1e-05 25.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEZ41619.1 - 4.2e-12 46.3 0.3 0.00069 19.7 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ41619.1 - 1.9e-11 44.2 0.3 0.00041 20.3 0.0 3.9 3 2 1 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 KEZ41619.1 - 2.8e-11 44.2 0.0 0.00028 21.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 KEZ41619.1 - 3.9e-09 35.7 1.4 0.00089 18.0 0.0 3.0 4 0 0 4 4 4 2 TIP49 C-terminus AAA_25 PF13481.1 KEZ41619.1 - 6.1e-09 35.5 4.5 0.0096 15.3 0.0 4.5 2 2 2 4 4 4 3 AAA domain AAA_14 PF13173.1 KEZ41619.1 - 1.7e-08 34.3 0.0 0.0012 18.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KEZ41619.1 - 3.1e-08 33.2 0.0 0.0053 16.1 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.12 KEZ41619.1 - 9.5e-08 31.5 0.5 2.9e-07 30.0 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 KEZ41619.1 - 1.5e-07 30.7 0.0 0.0081 15.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KEZ41619.1 - 1.6e-07 30.7 0.3 0.0052 15.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEZ41619.1 - 5.3e-07 29.7 0.0 0.03 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.1 KEZ41619.1 - 1e-06 28.8 0.1 0.086 12.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 KEZ41619.1 - 1.2e-06 27.8 0.7 0.23 10.5 0.0 3.6 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 KEZ41619.1 - 1.5e-06 28.5 0.0 0.087 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KEZ41619.1 - 1.7e-06 28.0 0.0 0.0023 17.7 0.0 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KEZ41619.1 - 1.9e-06 27.6 0.2 0.095 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 KEZ41619.1 - 5.5e-06 25.4 0.0 0.015 14.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_19 PF13245.1 KEZ41619.1 - 5.9e-06 25.9 9.3 0.0088 15.7 0.0 3.4 4 0 0 4 4 2 2 Part of AAA domain Parvo_NS1 PF01057.12 KEZ41619.1 - 7e-06 25.1 0.0 0.042 12.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KEZ41619.1 - 7.2e-06 25.8 0.0 4.9 6.7 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase Vps4_C PF09336.5 KEZ41619.1 - 7.7e-06 25.7 0.1 4.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 KEZ41619.1 - 1e-05 25.6 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 KEZ41619.1 - 1.5e-05 24.5 0.0 0.17 11.3 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 KEZ41619.1 - 1.6e-05 24.6 0.1 0.085 12.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.22 KEZ41619.1 - 2.9e-05 24.4 0.0 0.34 11.2 0.0 3.7 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 KEZ41619.1 - 5.4e-05 22.9 0.0 0.45 10.1 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_30 PF13604.1 KEZ41619.1 - 0.0001 21.9 0.0 0.32 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KEZ41619.1 - 0.00012 21.3 0.2 0.47 9.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KEZ41619.1 - 0.00017 21.2 0.0 0.59 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KEZ41619.1 - 0.00042 19.2 0.1 0.46 9.3 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain AAA_11 PF13086.1 KEZ41619.1 - 0.0005 19.7 0.0 0.81 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 KEZ41619.1 - 0.001 18.8 0.2 0.65 9.6 0.0 3.7 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 KEZ41619.1 - 0.0015 17.6 0.0 1.5 7.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KEZ41619.1 - 0.002 17.6 0.0 0.27 10.7 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 KEZ41619.1 - 0.0099 15.0 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase KAP_NTPase PF07693.9 KEZ41619.1 - 0.012 14.6 0.5 1.4 7.8 0.0 3.5 2 2 1 4 4 4 0 KAP family P-loop domain UPF0079 PF02367.12 KEZ41619.1 - 0.025 14.2 0.1 9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KEZ41619.1 - 0.027 13.9 0.5 1.6 8.1 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 KEZ41619.1 - 0.038 12.8 0.0 1.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.11 KEZ41619.1 - 0.059 12.1 0.0 7.7 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase UFD1 PF03152.9 KEZ41619.1 - 0.061 12.4 0.0 5.9 5.9 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zot PF05707.7 KEZ41619.1 - 0.071 12.5 0.2 16 4.8 0.1 3.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 KEZ41619.1 - 0.11 11.6 0.4 11 5.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MobB PF03205.9 KEZ41619.1 - 0.12 12.0 1.3 3.5 7.3 0.0 3.4 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 KEZ41619.1 - 0.15 12.4 1.2 4.7 7.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain EnY2 PF10163.4 KEZ41620.1 - 0.079 12.9 0.0 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 Transcription factor e(y)2 ABC_tran PF00005.22 KEZ41621.1 - 3.7e-31 108.2 0.0 7.9e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KEZ41621.1 - 5.3e-22 78.5 9.9 5.3e-22 78.5 6.9 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KEZ41621.1 - 5.4e-05 22.5 0.0 0.00054 19.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ41621.1 - 0.0023 17.9 0.0 0.77 9.6 0.0 2.7 2 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 KEZ41621.1 - 0.0063 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KEZ41621.1 - 0.025 14.4 0.1 0.23 11.4 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KEZ41621.1 - 0.032 13.7 0.1 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRAM_LAG1_CLN8 PF03798.11 KEZ41622.1 - 7.7e-34 116.9 16.0 1.3e-33 116.2 11.1 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KEZ41622.1 - 5.2e-25 86.7 0.1 1e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 TRAM1-like protein Glyco_hydro_3 PF00933.16 KEZ41623.1 - 8.1e-59 199.0 0.0 1.1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ41623.1 - 2.8e-38 131.6 0.0 4.1e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ41623.1 - 9e-07 28.7 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF716 PF04819.7 KEZ41624.1 - 0.042 13.2 1.6 0.053 12.9 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF716) Lipase_GDSL_2 PF13472.1 KEZ41625.1 - 2.7e-16 60.2 0.9 3.2e-16 59.9 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ41625.1 - 3.8e-11 43.2 0.2 9e-11 42.0 0.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase fn3 PF00041.16 KEZ41626.1 - 1.8e-12 47.2 6.1 1.4e-07 31.4 0.2 3.9 3 1 1 4 4 4 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 KEZ41626.1 - 2.1e-11 44.2 0.1 4.2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ41626.1 - 0.00067 19.5 0.0 0.0022 17.8 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KEZ41626.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.2 KEZ41627.1 - 0.00028 20.5 0.0 0.00054 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KEZ41627.1 - 0.00074 19.0 0.1 0.0019 17.8 0.1 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ41627.1 - 0.0028 17.3 0.4 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat DUF4243 PF14027.1 KEZ41628.1 - 3.6e-64 217.2 0.1 4.3e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) FAD_binding_3 PF01494.14 KEZ41629.1 - 1.6e-37 129.4 0.0 2.6e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Fungal_trans PF04082.13 KEZ41630.1 - 4.3e-13 48.7 0.0 6.7e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 KEZ41631.1 - 1.9e-72 244.7 0.1 2.1e-37 129.0 0.0 3.0 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ41631.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ41631.1 - 0.021 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family SQS_PSY PF00494.14 KEZ41632.1 - 2.4e-38 131.9 0.0 3.5e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CFEM PF05730.6 KEZ41633.1 - 5e-13 48.6 16.1 9.1e-13 47.8 11.1 1.4 1 0 0 1 1 1 1 CFEM domain NACHT PF05729.7 KEZ41634.1 - 1.9e-12 47.1 0.0 4.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ41634.1 - 2.3e-06 27.7 0.2 1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ41634.1 - 3.4e-06 27.2 0.0 2.2e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain WSC PF01822.14 KEZ41634.1 - 4.1e-05 23.4 7.2 0.0001 22.1 5.0 1.7 1 0 0 1 1 1 1 WSC domain AAA PF00004.24 KEZ41634.1 - 0.00025 21.2 0.0 0.0015 18.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KEZ41634.1 - 0.00073 19.3 0.0 0.0022 17.7 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 KEZ41634.1 - 0.012 14.8 0.0 0.039 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KEZ41634.1 - 0.012 14.9 0.0 0.08 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEZ41634.1 - 0.015 16.0 0.0 0.079 13.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEZ41634.1 - 0.016 15.4 0.0 0.063 13.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KEZ41634.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 KEZ41634.1 - 0.048 13.5 1.1 0.33 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEZ41634.1 - 0.05 13.9 0.0 0.35 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KEZ41634.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KEZ41634.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 KEZ41634.1 - 0.12 11.3 4.8 0.99 8.3 0.0 2.6 3 0 0 3 3 3 0 KAP family P-loop domain AAA_10 PF12846.2 KEZ41634.1 - 0.17 11.2 3.6 0.12 11.7 0.1 2.5 2 1 1 3 3 3 0 AAA-like domain AAA_23 PF13476.1 KEZ41634.1 - 0.18 12.1 0.0 0.85 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KEZ41634.1 - 1.3 7.3 2.1 1 7.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2236 PF09995.4 KEZ41635.1 - 4.5e-08 32.6 1.2 4.9e-08 32.5 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) adh_short_C2 PF13561.1 KEZ41636.1 - 8.2e-31 107.6 1.5 9.3e-31 107.4 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ41636.1 - 2.2e-28 99.2 2.1 3.1e-28 98.7 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41636.1 - 8.8e-12 45.0 0.8 1.3e-11 44.5 0.5 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 KEZ41636.1 - 0.018 14.6 0.6 0.032 13.8 0.1 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus Eno-Rase_NADH_b PF12242.3 KEZ41636.1 - 0.068 12.9 3.4 0.16 11.7 0.9 2.3 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PSK_trans_fac PF07704.6 KEZ41636.1 - 0.21 12.3 2.8 1.6 9.4 0.1 2.7 2 1 1 3 3 3 0 Rv0623-like transcription factor adh_short PF00106.20 KEZ41637.1 - 8.1e-05 22.6 0.3 0.00014 21.8 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEZ41637.1 - 0.0038 17.2 0.1 0.0058 16.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KEZ41637.1 - 0.0056 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KEZ41637.1 - 0.025 14.6 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ41637.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.1 KEZ41637.1 - 0.066 12.9 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KEZ41637.1 - 0.096 11.9 0.1 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.13 KEZ41637.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_2 PF00891.13 KEZ41639.1 - 1.8e-31 109.1 0.0 6.6e-31 107.3 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEZ41639.1 - 5.6e-06 26.9 0.0 9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41639.1 - 8.8e-05 22.1 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ41639.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ41639.1 - 0.023 15.0 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41639.1 - 0.029 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.6 KEZ41640.1 - 2.5e-23 82.7 0.0 4e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 KEZ41641.1 - 3.3e-12 45.8 0.8 4.8e-12 45.2 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 KEZ41642.1 - 6.3e-25 87.9 0.7 1.1e-24 87.1 0.5 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.6 KEZ41642.1 - 1.6e-21 76.9 0.0 3.3e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2424 PF10340.4 KEZ41642.1 - 1.6e-13 50.0 0.0 2.7e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KEZ41642.1 - 0.0038 16.4 0.0 0.039 13.1 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ41642.1 - 0.0048 16.6 0.1 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Con-6 PF10346.4 KEZ41643.1 - 2.1e-32 110.2 6.0 5.6e-17 60.8 0.7 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 KEZ41643.1 - 0.0022 17.5 0.2 0.62 9.5 0.1 2.1 2 0 0 2 2 2 2 SpoIIIAH-like protein Toxin_52 PF15605.1 KEZ41643.1 - 0.0096 15.7 0.2 2.8 7.8 0.0 2.1 2 0 0 2 2 2 2 Putative toxin 52 DUF4195 PF13836.1 KEZ41643.1 - 0.053 13.2 0.1 5.4 6.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4195) ATP-synt_DE PF00401.15 KEZ41643.1 - 1.8 8.5 6.8 5.8 6.8 0.5 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain NACHT PF05729.7 KEZ41644.1 - 0.019 14.6 0.0 0.073 12.7 0.0 2.1 1 1 0 1 1 1 0 NACHT domain Vac_Fusion PF02346.11 KEZ41644.1 - 0.025 13.9 0.1 0.085 12.2 0.0 1.9 1 0 0 1 1 1 0 Chordopoxvirus fusion protein Phage_GPO PF05929.6 KEZ41644.1 - 0.072 12.3 0.9 0.2 10.8 0.0 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Img2 PF05046.9 KEZ41644.1 - 0.087 13.0 1.1 6.1 7.1 0.1 3.3 2 1 1 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) CorA PF01544.13 KEZ41647.1 - 3.1e-14 52.6 0.4 1.3e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Dynamin_N PF00350.18 KEZ41649.1 - 5.2e-33 114.2 0.0 9.2e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEZ41649.1 - 2.6e-17 62.5 0.0 5e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KEZ41649.1 - 6.8e-05 22.6 0.4 0.00034 20.4 0.2 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEZ41649.1 - 0.00064 19.6 0.0 0.0026 17.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ41649.1 - 0.001 19.5 0.0 0.0039 17.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 KEZ41649.1 - 0.038 14.3 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KEZ41649.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Med3 PF11593.3 KEZ41650.1 - 2 7.5 9.3 2.3 7.3 6.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4448 PF14610.1 KEZ41651.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DAP10 PF07213.6 KEZ41651.1 - 0.02 14.6 0.2 0.042 13.5 0.2 1.5 1 0 0 1 1 1 0 DAP10 membrane protein VSP PF03302.8 KEZ41651.1 - 0.051 12.2 0.5 0.077 11.6 0.4 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Aldose_epim PF01263.15 KEZ41652.1 - 1.2e-48 165.7 0.3 1.6e-48 165.3 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase WSC PF01822.14 KEZ41653.1 - 0.0002 21.2 0.1 0.0002 21.2 0.1 3.4 1 1 3 4 4 4 1 WSC domain Collagen PF01391.13 KEZ41654.1 - 0.00047 19.6 24.5 0.00082 18.8 17.0 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF605 PF04652.11 KEZ41654.1 - 0.0041 16.5 16.4 0.0044 16.4 11.3 1.1 1 0 0 1 1 1 1 Vta1 like Trypan_PARP PF05887.6 KEZ41654.1 - 0.22 11.3 21.0 0.12 12.1 9.0 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Corona_nucleoca PF00937.13 KEZ41654.1 - 0.3 9.9 12.8 0.39 9.6 8.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PAT1 PF09770.4 KEZ41654.1 - 0.73 7.9 19.7 0.96 7.6 13.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PA26 PF04636.8 KEZ41654.1 - 2.3 6.8 5.6 2.8 6.5 3.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Suf PF05843.9 KEZ41654.1 - 2.4 7.8 14.3 3.2 7.3 9.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Raftlin PF15250.1 KEZ41654.1 - 2.7 6.3 8.1 3.7 5.9 5.6 1.1 1 0 0 1 1 1 0 Raftlin Secretin_N_2 PF07655.8 KEZ41654.1 - 3.7 8.0 16.2 8.5 6.8 11.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Hid1 PF12722.2 KEZ41654.1 - 5.6 4.5 14.8 7.2 4.1 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_23 PF13489.1 KEZ41655.1 - 5.2e-19 68.5 0.2 8.8e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41655.1 - 3.4e-09 36.4 0.0 3.3e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41655.1 - 1.6e-08 35.1 0.1 2.8e-07 31.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41655.1 - 5.1e-08 33.2 0.0 3.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ41655.1 - 3.6e-06 27.2 0.0 1.9e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41655.1 - 7.8e-05 23.0 0.0 0.00034 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ41655.1 - 0.00013 21.1 0.0 0.00013 21.1 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_2 PF00891.13 KEZ41655.1 - 0.0004 19.6 0.0 0.00061 19.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 KEZ41655.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEZ41655.1 - 0.0016 17.6 0.0 0.0048 16.0 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KEZ41655.1 - 0.0016 17.8 0.0 0.0045 16.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEZ41655.1 - 0.0026 16.9 0.0 0.023 13.7 0.0 2.2 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KEZ41655.1 - 0.0029 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase p450 PF00067.17 KEZ41656.1 - 1.1e-45 156.0 0.0 1.4e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GRDA PF04723.9 KEZ41656.1 - 0.023 14.3 0.1 0.73 9.5 0.0 2.5 3 0 0 3 3 3 0 Glycine reductase complex selenoprotein A Pro-kuma_activ PF09286.6 KEZ41658.1 - 1.6e-24 86.6 0.0 2.9e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KEZ41658.1 - 0.00016 20.9 0.5 0.00026 20.2 0.3 1.3 1 0 0 1 1 1 1 Subtilase family DUF4255 PF14065.1 KEZ41658.1 - 0.084 12.3 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) MFS_1 PF07690.11 KEZ41659.1 - 2.7e-22 78.9 42.7 1.3e-19 70.1 19.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ41659.1 - 2.1e-07 29.5 19.9 6.4e-07 27.9 13.8 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mem_trans PF03547.13 KEZ41660.1 - 1.1e-21 76.6 2.0 3.2e-21 75.0 1.4 1.6 1 1 0 1 1 1 1 Membrane transport protein DUF2929 PF11151.3 KEZ41660.1 - 3.4 7.7 8.2 0.31 11.1 1.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) zf-met PF12874.2 KEZ41661.1 - 1.9e-36 123.1 29.3 7.2e-06 26.0 0.2 7.3 7 0 0 7 7 7 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEZ41661.1 - 1.5e-33 114.1 40.4 4e-06 26.8 0.4 7.3 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KEZ41661.1 - 4.6e-22 78.0 37.1 0.004 17.2 0.2 7.0 1 1 6 7 7 7 7 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KEZ41661.1 - 3.9e-18 64.6 25.3 0.014 15.7 0.1 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 KEZ41661.1 - 5.7e-14 51.3 20.3 0.17 11.6 0.0 7.5 7 0 0 7 7 7 7 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 KEZ41661.1 - 4.8e-12 45.3 22.0 0.13 12.6 0.0 7.4 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KEZ41661.1 - 1.4e-09 37.5 36.0 0.69 9.9 0.3 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-3CxxC PF13695.1 KEZ41661.1 - 6.3e-06 26.3 25.2 1.1 9.5 1.0 6.4 1 1 4 6 6 6 2 Zinc-binding domain LIM PF00412.17 KEZ41661.1 - 1.3e-05 25.1 30.6 0.35 10.9 3.1 5.3 1 1 5 6 6 6 6 LIM domain C1_2 PF03107.11 KEZ41661.1 - 0.00023 21.2 35.1 3 8.0 0.2 7.2 7 0 0 7 7 7 4 C1 domain zf-FCS PF06467.9 KEZ41661.1 - 0.0011 18.5 13.7 5.6 6.6 0.0 6.5 7 0 0 7 7 7 1 MYM-type Zinc finger with FCS sequence motif DUF2256 PF10013.4 KEZ41661.1 - 0.0013 18.4 18.7 25 4.7 0.0 7.0 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_3 PF07649.7 KEZ41661.1 - 0.0017 18.3 18.1 42 4.2 0.0 7.0 7 0 0 7 7 7 0 C1-like domain Evr1_Alr PF04777.8 KEZ41661.1 - 0.0028 17.5 32.5 0.39 10.6 0.1 6.5 1 1 4 5 5 5 1 Erv1 / Alr family C1_4 PF07975.7 KEZ41661.1 - 0.011 15.7 29.4 1.7 8.7 2.3 4.7 1 1 5 6 6 6 0 TFIIH C1-like domain zf-DBF PF07535.7 KEZ41661.1 - 0.013 15.1 42.2 3.4 7.4 0.2 7.2 4 3 2 6 6 6 0 DBF zinc finger Sgf11 PF08209.6 KEZ41661.1 - 0.015 14.6 21.4 7.1 6.0 0.0 6.9 7 0 0 7 7 7 0 Sgf11 (transcriptional regulation protein) zf-DNA_Pol PF08996.5 KEZ41661.1 - 0.056 12.8 19.2 0.27 10.5 1.0 3.9 1 1 4 5 5 5 0 DNA Polymerase alpha zinc finger Prok-RING_1 PF14446.1 KEZ41661.1 - 0.062 13.0 19.0 7 6.4 0.0 6.7 7 0 0 7 7 7 0 Prokaryotic RING finger family 1 zf-H2C2_2 PF13465.1 KEZ41661.1 - 0.12 12.7 24.9 28 5.2 0.1 7.5 7 0 0 7 7 7 0 Zinc-finger double domain zf-AN1 PF01428.11 KEZ41661.1 - 0.13 12.2 32.3 5.7 6.8 1.3 7.4 5 1 2 7 7 7 0 AN1-like Zinc finger HypA PF01155.14 KEZ41661.1 - 0.37 10.4 25.6 6.2 6.5 1.4 4.3 1 1 3 4 4 4 0 Hydrogenase expression/synthesis hypA family Myb_DNA-bind_3 PF12776.2 KEZ41661.1 - 1 10.0 11.5 0.2 12.3 2.6 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Rad50_zn_hook PF04423.9 KEZ41661.1 - 1.7 8.2 20.8 4.8 6.7 0.2 6.4 7 0 0 7 7 7 0 Rad50 zinc hook motif PyrI_C PF02748.10 KEZ41661.1 - 1.7 8.1 19.0 11 5.5 0.0 6.2 2 2 5 7 7 7 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.5 KEZ41661.1 - 1.8 8.5 33.2 20 5.2 0.2 7.1 6 1 1 7 7 7 0 Zinc ribbon domain Ribonuc_L-PSP PF01042.16 KEZ41662.1 - 2.5e-09 36.9 0.0 4.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Zn_clus PF00172.13 KEZ41663.1 - 0.018 14.9 5.3 0.031 14.1 3.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ41663.1 - 0.047 12.5 0.2 0.15 10.9 0.1 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain KCl_Cotrans_1 PF03522.10 KEZ41663.1 - 0.62 9.6 3.2 1.8 8.1 2.2 1.8 1 0 0 1 1 1 0 K-Cl Co-transporter type 1 (KCC1) RTA1 PF04479.8 KEZ41664.1 - 6.1e-55 186.1 14.3 8.3e-55 185.7 9.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KEZ41664.1 - 0.0023 17.6 1.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Fungal_trans_2 PF11951.3 KEZ41665.1 - 0.00011 20.9 3.5 0.00015 20.5 2.4 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 KEZ41666.1 - 2.5e-27 95.2 0.0 8e-22 77.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF1080 PF06439.6 KEZ41666.1 - 0.00084 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) DUF608 PF04685.8 KEZ41666.1 - 0.052 12.2 0.9 0.083 11.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Laminin_G_2 PF02210.19 KEZ41666.1 - 0.084 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain TATR PF03430.8 KEZ41667.1 - 4.8 5.6 5.2 5.3 5.5 3.6 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator MHYT PF03707.11 KEZ41668.1 - 0.00079 19.4 3.7 0.00079 19.4 2.6 4.8 5 1 0 5 5 5 2 Bacterial signalling protein N terminal repeat MFS_1 PF07690.11 KEZ41669.1 - 2.1e-28 99.0 12.7 4.6e-28 97.9 7.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ41669.1 - 0.0037 17.0 0.8 0.0037 17.0 0.5 1.9 2 0 0 2 2 2 1 MFS_1 like family TauD PF02668.11 KEZ41670.1 - 4.5e-56 190.3 0.1 6.4e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3918 PF13056.1 KEZ41671.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Pectate_lyase_3 PF12708.2 KEZ41672.1 - 2e-54 185.1 15.2 1.1e-45 156.5 5.8 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein DNase_NucA_NucB PF14040.1 KEZ41672.1 - 0.0046 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB End_N_terminal PF12218.3 KEZ41672.1 - 0.011 15.1 0.7 0.045 13.2 0.0 2.2 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase DUF917 PF06032.7 KEZ41674.1 - 1.5e-109 365.7 0.0 2.4e-109 365.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KEZ41674.1 - 4.3e-45 154.0 7.0 4.2e-43 147.5 2.8 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEZ41674.1 - 1.4e-28 99.5 2.4 3.2e-26 91.9 0.3 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 KEZ41674.1 - 0.0001 20.8 0.5 0.19 9.9 0.0 2.7 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 KEZ41674.1 - 0.0036 16.6 1.9 0.0095 15.2 0.0 2.5 4 0 0 4 4 4 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 KEZ41674.1 - 0.025 13.5 0.1 1.9 7.3 0.0 2.9 3 0 0 3 3 3 0 StbA protein Transp_cyt_pur PF02133.10 KEZ41675.1 - 2e-92 310.0 32.1 2.4e-92 309.7 22.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Thioredoxin PF00085.15 KEZ41676.1 - 8e-16 57.6 0.0 9.6e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KEZ41676.1 - 0.00022 21.2 0.1 0.0057 16.7 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 KEZ41676.1 - 0.00026 20.5 0.1 0.0078 15.7 0.1 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KEZ41676.1 - 0.0031 17.1 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 KEZ41676.1 - 0.0033 17.5 0.3 0.042 14.0 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KEZ41676.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain APH PF01636.18 KEZ41677.1 - 0.0015 18.3 0.4 0.25 11.0 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 KEZ41677.1 - 0.051 12.7 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) C2 PF00168.25 KEZ41677.1 - 0.12 12.1 0.1 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 C2 domain WD40 PF00400.27 KEZ41678.1 - 1.7e-19 68.8 18.9 2e-09 36.9 0.1 9.9 11 0 0 11 11 11 2 WD domain, G-beta repeat NACHT PF05729.7 KEZ41678.1 - 7.3e-08 32.2 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ41678.1 - 2.3e-05 24.4 0.4 0.00014 21.8 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain Nup160 PF11715.3 KEZ41678.1 - 0.00012 20.3 5.1 0.19 9.8 0.0 4.0 1 1 2 4 4 4 1 Nucleoporin Nup120/160 AAA_22 PF13401.1 KEZ41678.1 - 0.00032 20.8 0.0 0.0008 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEZ41678.1 - 0.011 15.2 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ41678.1 - 0.025 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 KEZ41678.1 - 0.038 14.2 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEZ41678.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KEZ41678.1 - 0.15 12.9 0.0 0.46 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Coatomer_WDAD PF04053.9 KEZ41678.1 - 0.46 9.2 0.2 2.6 6.7 0.0 1.8 1 1 2 3 3 3 0 Coatomer WD associated region FeThRed_B PF02943.10 KEZ41679.1 - 0.64 9.7 6.5 0.73 9.5 4.5 1.2 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Defensin_2 PF01097.13 KEZ41680.1 - 5.3e-08 32.4 5.5 7.6e-08 31.9 3.8 1.2 1 0 0 1 1 1 1 Arthropod defensin Toxin_38 PF14866.1 KEZ41680.1 - 0.00035 20.5 3.3 0.00053 20.0 2.3 1.2 1 0 0 1 1 1 1 Potassium channel toxin Gamma-thionin PF00304.15 KEZ41680.1 - 0.038 14.0 2.5 0.056 13.4 1.7 1.2 1 0 0 1 1 1 0 Gamma-thionin family MFS_1 PF07690.11 KEZ41681.1 - 4.7e-33 114.3 29.2 6.6e-33 113.8 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ41681.1 - 6.8e-16 57.8 4.6 6.8e-16 57.8 3.2 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KEZ41681.1 - 1.5e-06 26.7 5.7 1.5e-06 26.7 4.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 KEZ41682.1 - 1.1e-24 86.7 0.4 1.8e-24 86.0 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41682.1 - 7.1e-08 32.2 9.7 1.5e-07 31.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KEZ41683.1 - 3.5e-10 39.8 0.0 5.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41683.1 - 2.2e-08 34.4 0.0 7.2e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41683.1 - 2.3e-07 31.3 0.0 1.3e-06 28.9 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41683.1 - 4.5e-07 29.5 0.0 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41683.1 - 3.3e-06 27.4 0.0 7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ41683.1 - 0.006 16.6 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ41683.1 - 0.024 15.0 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ41683.1 - 0.038 13.1 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 KEZ41683.1 - 0.047 12.6 0.0 0.092 11.7 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FAD_binding_3 PF01494.14 KEZ41684.1 - 9.2e-62 209.1 0.1 3.6e-23 82.1 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain Phe_hydrox_dim PF07976.7 KEZ41684.1 - 9.7e-57 191.2 0.0 2.1e-56 190.1 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KEZ41684.1 - 0.00024 21.4 0.1 0.022 15.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ41684.1 - 0.00033 19.8 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KEZ41684.1 - 0.0012 17.4 0.0 0.0019 16.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KEZ41684.1 - 0.0042 16.0 0.0 0.0085 15.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ41684.1 - 0.0047 15.8 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ41684.1 - 0.0088 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ41684.1 - 0.08 11.8 0.2 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KEZ41684.1 - 0.24 10.2 0.0 0.49 9.1 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.13 KEZ41685.1 - 3e-06 26.3 1.0 8.9e-06 24.7 0.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 KEZ41686.1 - 3.2e-43 147.6 0.0 4e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KEZ41686.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S49 Acyl-CoA_dh_1 PF00441.19 KEZ41687.1 - 1e-29 103.5 1.6 1.4e-29 103.1 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEZ41687.1 - 7.4e-24 84.4 0.0 1.8e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ41687.1 - 1.7e-17 62.6 1.8 3.9e-17 61.5 1.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AMP-binding PF00501.23 KEZ41688.1 - 1.6e-59 201.3 0.4 2.7e-45 154.5 0.1 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ41688.1 - 1.3e-08 35.6 0.1 5.4e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PGAP1 PF07819.8 KEZ41690.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein NYD-SP28 PF14772.1 KEZ41690.1 - 0.061 13.4 5.6 0.057 13.5 0.7 2.7 2 1 1 3 3 3 0 Sperm tail SIP1 PF04938.7 KEZ41690.1 - 0.32 10.3 5.4 0.71 9.1 3.7 1.5 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) COesterase PF00135.23 KEZ41691.1 - 1.5e-37 129.5 0.1 8.2e-26 90.8 0.5 3.1 1 1 2 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ41691.1 - 0.00092 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HgmA PF04209.8 KEZ41692.1 - 2.2e-126 421.7 0.0 2.5e-126 421.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Sugar_tr PF00083.19 KEZ41693.1 - 1.9e-69 234.3 27.2 2.2e-69 234.1 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41693.1 - 4.8e-14 51.8 42.2 6e-13 48.2 11.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_q3 PF00499.15 KEZ41693.1 - 6.3 6.5 12.3 2.5 7.8 5.5 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 AMP-binding PF00501.23 KEZ41694.1 - 1.1e-49 168.9 0.1 1.8e-30 105.6 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ41694.1 - 0.00036 21.4 0.0 0.00072 20.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 KEZ41695.1 - 4.4e-22 78.6 0.0 8.5e-22 77.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ41695.1 - 7.6e-07 28.3 5.4 0.0006 18.8 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ41695.1 - 9.7e-06 24.6 0.1 1.8e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KEZ41695.1 - 6.1e-05 22.0 1.2 0.00066 18.7 0.8 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KEZ41695.1 - 8.3e-05 21.3 1.3 0.045 12.3 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KEZ41695.1 - 0.00013 21.8 0.4 0.00038 20.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ41695.1 - 0.0018 18.3 0.2 0.014 15.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ41695.1 - 0.0029 17.9 1.0 1.1 9.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ41695.1 - 0.004 15.6 2.5 0.38 9.1 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ41695.1 - 0.045 13.6 3.2 0.75 9.6 2.2 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ41695.1 - 0.19 10.5 1.6 0.32 9.8 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HgmA PF04209.8 KEZ41696.1 - 5.4e-120 400.6 0.0 6.5e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Thiolase_N PF00108.18 KEZ41697.1 - 1e-55 188.5 0.3 2.6e-55 187.2 0.0 1.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEZ41697.1 - 2e-45 153.1 0.3 4.2e-45 152.1 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KEZ41697.1 - 3.2e-05 23.8 0.0 8.7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KEZ41697.1 - 0.00025 20.6 0.2 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KEZ41697.1 - 0.0086 15.5 0.2 0.021 14.3 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain RCR PF12273.3 KEZ41699.1 - 0.093 13.2 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF543 PF04418.7 KEZ41700.1 - 0.34 10.8 1.5 0.6 10.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Git3 PF11710.3 KEZ41702.1 - 3.8e-16 59.2 5.5 1.2e-15 57.6 3.8 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KEZ41702.1 - 4.9e-06 25.8 0.4 6.4e-06 25.4 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KEZ41702.1 - 7.9e-06 25.5 0.1 2e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Grp1_Fun34_YaaH PF01184.14 KEZ41703.1 - 3.6e-23 81.9 13.6 5.2e-23 81.4 9.4 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3961 PF13106.1 KEZ41703.1 - 0.026 14.0 2.0 0.096 12.2 1.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) GFA PF04828.9 KEZ41704.1 - 3.3e-23 81.4 0.1 4.7e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KEZ41704.1 - 0.0021 17.1 0.9 0.0057 15.8 0.1 2.0 2 0 0 2 2 2 1 zinc-ribbon domain DNA_ligase_ZBD PF03119.11 KEZ41704.1 - 0.0029 17.2 0.1 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain UPF0547 PF10571.4 KEZ41704.1 - 0.022 14.4 2.5 0.042 13.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.11 KEZ41704.1 - 0.034 13.8 1.1 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DZR PF12773.2 KEZ41704.1 - 0.051 13.3 2.7 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon A2L_zn_ribbon PF08792.5 KEZ41704.1 - 0.068 12.6 0.1 0.068 12.6 0.0 2.4 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-IS66 PF13005.2 KEZ41704.1 - 0.86 9.6 0.1 0.86 9.6 0.0 2.9 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 MFS_1 PF07690.11 KEZ41705.1 - 2.8e-26 92.0 28.3 4.3e-26 91.4 19.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KEZ41705.1 - 2e-10 39.8 6.1 1.4e-09 37.0 4.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41705.1 - 0.00011 22.0 3.6 0.0002 21.2 2.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG22 PF11700.3 KEZ41705.1 - 4.8 5.5 22.5 0.028 12.9 8.0 2.1 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like AAA PF00004.24 KEZ41706.1 - 3.7e-16 59.5 0.0 7.5e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ41706.1 - 9.1e-05 22.6 1.4 0.021 14.9 0.9 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ41706.1 - 0.00012 22.1 0.1 0.00067 19.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KEZ41706.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KEZ41706.1 - 0.0048 15.9 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KEZ41706.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 KEZ41706.1 - 0.026 14.0 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEZ41706.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEZ41706.1 - 0.15 12.9 0.1 0.15 12.9 0.1 3.4 3 2 0 3 3 3 0 AAA domain Desmo_N PF06771.6 KEZ41708.1 - 0.034 14.0 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus Pkinase PF00069.20 KEZ41709.1 - 6.1e-07 28.8 0.0 1.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Glyco_tran_28_C PF04101.11 KEZ41709.1 - 0.031 13.9 0.0 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain vWA-TerF-like PF10138.4 KEZ41709.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 vWA found in TerF C terminus Fungal_trans PF04082.13 KEZ41710.1 - 8.1e-13 47.8 0.0 1.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ligase_CoA PF00549.14 KEZ41711.1 - 1.5e-15 57.1 0.2 1.5e-15 57.1 0.1 1.9 3 0 0 3 3 3 1 CoA-ligase CoA_binding PF02629.14 KEZ41711.1 - 3.3e-15 56.3 2.7 1.6e-14 54.1 0.1 2.6 2 1 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 KEZ41711.1 - 6.4e-10 38.7 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KEZ41711.1 - 0.045 13.9 0.4 0.43 10.7 0.0 2.3 2 1 0 2 2 2 0 CoA binding domain ATP-grasp_2 PF08442.5 KEZ41712.1 - 1.9e-51 174.3 0.0 2.8e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KEZ41712.1 - 1.3e-18 67.0 0.6 2.4e-18 66.1 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KEZ41712.1 - 1.5e-05 24.3 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 KEZ41712.1 - 0.0018 17.8 0.1 0.0044 16.6 0.1 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CPSase_L_D2 PF02786.12 KEZ41712.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 KEZ41712.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.11 KEZ41713.1 - 1e-27 96.8 24.3 1.3e-27 96.4 16.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.1 KEZ41713.1 - 0.78 9.7 5.4 0.15 12.0 0.7 2.1 2 1 0 2 2 2 0 Stage V sporulation protein AB DUF4231 PF14015.1 KEZ41713.1 - 6.1 6.8 15.3 0.59 10.1 0.6 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DUF1996 PF09362.5 KEZ41714.1 - 1.4e-80 270.3 0.1 2e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_2 PF12796.2 KEZ41714.1 - 2.3e-65 216.9 1.4 2.3e-17 63.0 0.0 7.6 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41714.1 - 1.2e-45 151.1 14.5 9.3e-07 28.3 0.0 14.3 16 0 0 16 16 16 8 Ankyrin repeat Ank_4 PF13637.1 KEZ41714.1 - 2.1e-45 152.3 7.6 3.3e-12 46.5 0.0 12.0 6 3 6 12 12 12 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ41714.1 - 6.4e-44 147.0 7.3 5.8e-09 35.9 0.0 12.5 5 3 8 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ41714.1 - 1.2e-36 121.0 4.3 8.6e-05 22.4 0.0 13.7 14 0 0 14 14 14 6 Ankyrin repeat Abhydrolase_6 PF12697.2 KEZ41714.1 - 0.00013 21.9 0.1 0.0004 20.3 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ41714.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEZ41714.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEZ41714.1 - 0.015 14.6 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Recombinase PF07508.8 KEZ41714.1 - 0.28 11.4 0.0 28 5.0 0.0 3.4 3 1 1 4 4 4 0 Recombinase DUF676 PF05057.9 KEZ41716.1 - 1.9e-06 27.3 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEZ41716.1 - 6.2e-06 26.2 0.0 7.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ41716.1 - 3.8e-05 23.3 0.1 7.3e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEZ41716.1 - 6.4e-05 22.7 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KEZ41716.1 - 0.0021 17.7 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 KEZ41716.1 - 0.029 13.9 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 KEZ41716.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.20 KEZ41717.1 - 8.3e-35 120.1 0.0 1.7e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41717.1 - 9.8e-23 80.5 0.0 1.5e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.18 KEZ41717.1 - 4.9e-16 58.4 2.3 1.4e-15 57.0 1.6 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ41717.1 - 7.3e-11 41.8 0.3 2e-10 40.3 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like APH PF01636.18 KEZ41717.1 - 0.0017 18.0 4.7 0.01 15.5 0.3 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Cytokin-bind PF09265.5 KEZ41717.1 - 0.01 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Ribonuc_L-PSP PF01042.16 KEZ41718.1 - 1.7e-21 76.1 0.0 2.1e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MscS_porin PF12795.2 KEZ41719.1 - 0.0025 17.1 1.4 0.0046 16.3 0.3 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain NAD_binding_10 PF13460.1 KEZ41720.1 - 3.9e-20 72.6 0.0 4.6e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEZ41720.1 - 1.6e-08 34.2 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEZ41720.1 - 1.2e-07 31.2 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KEZ41720.1 - 0.0007 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KEZ41720.1 - 0.04 12.6 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KEZ41720.1 - 0.059 13.0 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 KR domain TPR_11 PF13414.1 KEZ41722.1 - 2.1e-09 36.8 2.6 2.1e-09 36.8 1.8 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KEZ41722.1 - 0.016 15.0 7.0 0.049 13.5 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ41722.1 - 0.064 12.8 3.5 0.98 9.1 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ41722.1 - 0.11 12.4 3.8 0.098 12.6 0.9 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ41722.1 - 3.5 8.5 6.0 4.3 8.2 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.1 KEZ41723.1 - 2e-11 44.4 0.0 6e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KEZ41723.1 - 4e-05 24.1 0.0 0.012 16.0 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ41723.1 - 6.9e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.3 KEZ41724.1 - 2.3e-10 39.6 0.0 4.9e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41724.1 - 0.031 14.1 0.4 0.031 14.1 0.3 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KEZ41725.1 - 1.5e-21 75.3 12.7 7.8e-05 22.4 0.0 7.4 6 2 0 6 6 6 5 WD domain, G-beta repeat p450 PF00067.17 KEZ41726.1 - 2.7e-77 260.2 0.0 3.4e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PLDc PF00614.17 KEZ41727.1 - 2.2e-15 55.8 1.2 1.8e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KEZ41727.1 - 1.7e-13 50.4 0.1 9.1e-07 28.6 0.0 3.7 3 0 0 3 3 3 3 PLD-like domain GLTP PF08718.6 KEZ41728.1 - 3e-43 147.3 0.0 1.2e-42 145.4 0.0 1.8 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) GrpE PF01025.14 KEZ41728.1 - 0.088 12.3 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 GrpE Glycos_transf_1 PF00534.15 KEZ41729.1 - 6.4e-17 61.4 0.0 1.2e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 KEZ41729.1 - 4.4e-11 42.8 0.0 1.1e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 KEZ41729.1 - 1.1e-06 28.8 0.0 3.7e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_114 PF03537.8 KEZ41730.1 - 3.5e-25 87.5 0.1 5.6e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.16 KEZ41731.1 - 0.044 13.4 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide deacetylase Abhydrolase_3 PF07859.8 KEZ41732.1 - 7.2e-29 100.8 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 KEZ41732.1 - 4e-13 49.1 0.1 8.2e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2424 PF10340.4 KEZ41732.1 - 4.3e-10 38.7 0.0 6.5e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Acetyltransf_10 PF13673.1 KEZ41732.1 - 7.5e-09 35.7 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEZ41732.1 - 1.6e-05 24.8 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEZ41732.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_5 PF12695.2 KEZ41732.1 - 0.0016 18.2 0.2 0.0031 17.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FR47 PF08445.5 KEZ41732.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein MAGUK_N_PEST PF10608.4 KEZ41732.1 - 0.086 13.2 0.0 0.35 11.3 0.0 2.0 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK MT-A70 PF05063.9 KEZ41732.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 MT-A70 adh_short PF00106.20 KEZ41733.1 - 6.6e-28 97.7 0.1 9.8e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41733.1 - 9.2e-09 35.2 0.1 2.1e-08 34.0 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ41733.1 - 4.6e-07 29.8 0.0 7.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.3 KEZ41733.1 - 0.00099 17.7 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.14 KEZ41733.1 - 0.0076 14.9 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEZ41734.1 - 3.5e-26 92.1 0.1 4.8e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41734.1 - 1.7e-09 37.5 0.1 2.9e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ41734.1 - 2.1e-08 34.2 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KEZ41734.1 - 0.0063 15.2 0.1 0.0086 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 KEZ41734.1 - 0.047 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 KEZ41734.1 - 0.057 12.8 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.14 KEZ41735.1 - 1.5e-05 24.2 0.2 3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Sulfotransfer_3 PF13469.1 KEZ41736.1 - 0.0044 17.9 1.7 3.3 8.6 0.1 2.3 1 1 0 2 2 2 2 Sulfotransferase family Gemini_mov PF01708.11 KEZ41736.1 - 0.053 13.0 0.7 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Geminivirus putative movement protein CENP-C_mid PF15620.1 KEZ41736.1 - 0.24 11.1 6.6 4.1 7.0 0.5 2.3 2 0 0 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region Lem_TRP PF08262.6 KEZ41736.1 - 0.34 10.7 2.1 24 5.0 0.1 2.5 2 0 0 2 2 2 0 Leucophaea maderae tachykinin-related peptide CFEM PF05730.6 KEZ41738.1 - 3.5e-17 61.9 12.5 6.6e-17 61.0 8.7 1.5 1 0 0 1 1 1 1 CFEM domain EutH PF04346.7 KEZ41738.1 - 0.0072 15.3 0.9 0.0072 15.3 0.6 1.8 1 1 1 2 2 2 1 Ethanolamine utilisation protein, EutH MARVEL PF01284.18 KEZ41740.1 - 0.0016 18.2 1.6 0.0023 17.7 1.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 KEZ41740.1 - 0.0018 17.6 4.9 0.0026 17.0 3.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1624 PF07786.7 KEZ41740.1 - 0.0038 16.5 1.5 0.0052 16.1 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) TctB PF07331.6 KEZ41740.1 - 0.017 14.7 3.1 0.039 13.5 2.0 1.5 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Ferric_reduct PF01794.14 KEZ41740.1 - 0.16 12.0 1.6 0.81 9.7 1.1 2.0 1 1 0 1 1 1 0 Ferric reductase like transmembrane component Tyrosinase PF00264.15 KEZ41742.1 - 1.3e-26 94.1 0.0 2.8e-26 93.0 0.0 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Peptidase_S9 PF00326.16 KEZ41743.1 - 4e-43 147.1 0.1 6.6e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 KEZ41743.1 - 1.1e-13 50.5 0.0 1.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Esterase_phd PF10503.4 KEZ41743.1 - 0.00063 19.0 0.2 0.0013 18.0 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KEZ41743.1 - 0.00084 19.2 1.5 0.0017 18.2 1.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEZ41743.1 - 0.001 18.5 0.1 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 KEZ41743.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KEZ41743.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SBP_bac_1 PF01547.20 KEZ41743.1 - 0.079 12.6 0.0 0.31 10.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein Glyco_hydro_1 PF00232.13 KEZ41744.1 - 1.5e-145 484.8 0.0 1.8e-145 484.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KEZ41744.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Bac_rhamnosid PF05592.6 KEZ41745.1 - 9.5e-177 588.2 0.0 1.2e-176 587.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 KEZ41745.1 - 1.8e-52 177.3 0.1 3.9e-52 176.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Cyclase PF04199.8 KEZ41746.1 - 1.7e-17 63.6 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 KEZ41747.1 - 1.2e-64 218.5 21.8 1.4e-64 218.3 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41747.1 - 3.4e-17 62.1 32.6 1.4e-10 40.4 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3272 PF11676.3 KEZ41747.1 - 0.066 13.2 0.2 0.066 13.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Fungal_trans PF04082.13 KEZ41748.1 - 2.5e-21 75.7 0.0 7.2e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41748.1 - 1.2e-06 28.2 7.7 2.1e-06 27.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KEZ41749.1 - 6.8e-50 169.4 0.0 8.4e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 KEZ41750.1 - 3.4e-44 150.6 0.0 5.2e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KEZ41750.1 - 6.6e-32 110.4 0.4 1.2e-31 109.5 0.3 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KEZ41750.1 - 1e-16 61.1 0.0 4.4e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AAA_17 PF13207.1 KEZ41750.1 - 6e-10 39.9 0.0 1.8e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain PP-binding PF00550.20 KEZ41750.1 - 1.2e-06 28.6 0.7 1e-05 25.6 0.2 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site SKI PF01202.17 KEZ41750.1 - 3.3e-05 23.7 0.0 7.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 KEZ41750.1 - 0.00011 22.4 0.0 0.00042 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ41750.1 - 0.00013 21.8 0.0 0.00069 19.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain adh_short PF00106.20 KEZ41750.1 - 0.00017 21.5 0.0 0.0016 18.4 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase AAA_PrkA PF08298.6 KEZ41750.1 - 0.00078 18.2 0.0 0.0014 17.3 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain PRK PF00485.13 KEZ41750.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ANF_receptor PF01094.23 KEZ41750.1 - 0.0029 16.4 0.3 0.23 10.1 0.0 2.3 2 0 0 2 2 2 1 Receptor family ligand binding region APS_kinase PF01583.15 KEZ41750.1 - 0.0036 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KEZ41750.1 - 0.0037 17.2 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ41750.1 - 0.0045 17.1 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KEZ41750.1 - 0.0046 16.8 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase-like family Zeta_toxin PF06414.7 KEZ41750.1 - 0.0074 15.4 0.0 0.019 14.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KEZ41750.1 - 0.0078 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEZ41750.1 - 0.013 15.6 0.0 0.044 13.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KEZ41750.1 - 0.023 13.6 0.0 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 KEZ41750.1 - 0.028 14.3 0.0 0.085 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 KEZ41750.1 - 0.046 13.2 0.1 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 KEZ41750.1 - 0.071 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 KEZ41750.1 - 0.078 12.7 0.7 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 KEZ41750.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEZ41750.1 - 0.095 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KEZ41750.1 - 0.1 12.2 0.2 0.26 10.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEZ41750.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CoaE PF01121.15 KEZ41750.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase RNA12 PF10443.4 KEZ41750.1 - 0.12 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein Arch_ATPase PF01637.13 KEZ41750.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 KEZ41750.1 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 KEZ41750.1 - 0.2 11.2 0.1 0.35 10.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KEZ41750.1 - 0.32 9.6 0.0 0.52 8.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein adh_short PF00106.20 KEZ41751.1 - 2.1e-19 70.0 0.1 8.4e-19 68.0 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41751.1 - 6.2e-05 22.7 0.1 0.00013 21.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEZ41751.1 - 0.044 13.2 0.0 0.65 9.3 0.0 2.5 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 KEZ41752.1 - 1.7e-21 76.6 0.0 2.5e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41752.1 - 7.7e-14 51.9 0.0 3.8e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41752.1 - 5.6e-11 42.7 0.0 1.2e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41752.1 - 9e-11 41.5 0.0 6.5e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41752.1 - 3e-10 40.6 0.0 3.3e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ41752.1 - 8.4e-09 35.7 0.0 3.3e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ41752.1 - 1.1e-07 31.2 0.0 7.8e-07 28.4 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEZ41752.1 - 1.5e-05 24.1 0.0 4.7e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KEZ41752.1 - 9.6e-05 22.4 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ41752.1 - 0.00048 20.1 0.0 0.0038 17.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ41752.1 - 0.002 17.5 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEZ41752.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KEZ41752.1 - 0.041 12.8 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 KEZ41752.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.7 KEZ41752.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 KEZ41752.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_15 PF09445.5 KEZ41752.1 - 0.17 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.11 KEZ41752.1 - 0.17 10.1 0.0 0.96 7.7 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NAD_binding_4 PF07993.7 KEZ41753.1 - 2.7e-64 216.4 0.0 5.6e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KEZ41753.1 - 1.4e-62 211.4 0.0 2.3e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KEZ41753.1 - 1.3e-11 44.4 0.0 2.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KEZ41753.1 - 1.1e-09 38.4 0.0 2.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KEZ41753.1 - 5.6e-08 33.6 0.0 4.1e-07 30.8 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 KEZ41753.1 - 3e-07 29.4 0.0 7.1e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEZ41753.1 - 0.00012 22.1 0.1 0.0014 18.6 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEZ41753.1 - 0.0053 16.6 0.1 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KEZ41753.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 KEZ41753.1 - 0.074 11.9 0.0 5 5.9 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Git3 PF11710.3 KEZ41754.1 - 1.2e-15 57.6 10.5 1.2e-15 57.6 7.3 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KEZ41754.1 - 1.2e-10 40.9 0.2 1.2e-10 40.9 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 KEZ41754.1 - 2.8e-08 33.2 5.9 3.6e-08 32.8 4.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SPX PF03105.14 KEZ41755.1 - 0.00012 21.9 1.4 0.076 12.7 0.0 2.2 2 0 0 2 2 2 2 SPX domain Sugar_tr PF00083.19 KEZ41756.1 - 1.8e-71 241.0 22.3 6e-69 232.7 15.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41756.1 - 8.1e-22 77.4 25.2 1.8e-21 76.2 13.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TPP_enzyme_N PF02776.13 KEZ41757.1 - 7.8e-47 158.9 0.2 5.9e-46 156.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEZ41757.1 - 1.9e-25 89.2 0.0 8.6e-25 87.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ41757.1 - 3.8e-17 62.3 0.0 6.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain adh_short PF00106.20 KEZ41758.1 - 5.9e-13 49.0 0.1 1.1e-12 48.1 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41758.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 KR domain Fungal_trans PF04082.13 KEZ41759.1 - 3.1e-05 22.9 0.2 4.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.17 KEZ41760.1 - 1.8e-34 118.7 0.0 2.6e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Con-6 PF10346.4 KEZ41761.1 - 1.3e-16 59.7 0.8 1.7e-16 59.3 0.6 1.2 1 0 0 1 1 1 1 Conidiation protein 6 AMP-binding PF00501.23 KEZ41762.1 - 2.1e-77 260.2 0.0 2.7e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ41762.1 - 5.3e-13 49.7 0.7 2.8e-12 47.3 0.1 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 KEZ41763.1 - 3.4e-18 65.3 1.3 5.9e-18 64.6 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ41763.1 - 2.1e-11 43.4 0.0 4.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ41763.1 - 1.5e-05 25.8 0.0 3.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 KEZ41763.1 - 0.022 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 KEZ41763.1 - 0.064 12.8 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.1 KEZ41764.1 - 2.9e-27 95.9 0.0 3.6e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ41764.1 - 3.7e-18 66.0 0.7 4.8e-18 65.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.8 KEZ41765.1 - 2.9e-47 160.9 0.0 3.8e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KEZ41765.1 - 1e-11 44.2 0.1 5.3e-11 41.9 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEZ41765.1 - 0.00023 20.4 0.0 0.04 13.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ41765.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ41765.1 - 0.069 13.0 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pyr_redox_3 PF13738.1 KEZ41766.1 - 9.4e-30 104.1 0.0 1.8e-29 103.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ41766.1 - 1.9e-14 52.7 0.0 2.9e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ41766.1 - 2.5e-09 36.4 0.9 6.4e-09 35.1 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEZ41766.1 - 1.2e-07 31.6 2.9 6.9e-07 29.2 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEZ41766.1 - 4.4e-07 29.9 0.0 1.5e-05 24.9 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ41766.1 - 0.0031 16.0 0.0 0.91 7.9 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.15 KEZ41766.1 - 0.0067 16.5 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KEZ41766.1 - 0.0079 15.1 0.7 0.07 12.0 0.1 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KEZ41766.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KEZ41766.1 - 0.018 13.9 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KEZ41766.1 - 0.024 13.7 0.1 1.3 7.9 0.0 2.2 1 1 1 2 2 2 0 FAD binding domain Thi4 PF01946.12 KEZ41766.1 - 0.052 12.6 0.1 0.099 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 KEZ41766.1 - 0.12 12.6 0.0 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Lactamase_B PF00753.22 KEZ41767.1 - 0.0021 17.7 4.4 0.01 15.4 3.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEZ41767.1 - 0.0063 16.0 0.1 0.0082 15.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.11 KEZ41768.1 - 1.5e-34 119.2 37.2 1.5e-34 119.2 25.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ41769.1 - 3e-19 68.9 0.2 4.7e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41769.1 - 0.00026 20.8 10.6 0.00056 19.7 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KEZ41770.1 - 8.7e-22 78.1 0.0 3.3e-21 76.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ41770.1 - 6.6e-19 67.4 0.0 1.3e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ41770.1 - 4.4e-10 39.4 0.0 1.5e-09 37.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ41770.1 - 1.7e-06 27.2 0.0 0.00053 18.9 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ41770.1 - 1.9e-05 24.4 0.3 0.012 15.3 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KEZ41770.1 - 0.0059 15.7 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase adh_short PF00106.20 KEZ41771.1 - 1.2e-17 64.3 0.0 2.1e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41771.1 - 4.7e-07 29.6 0.0 0.00034 20.3 0.0 2.1 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KEZ41771.1 - 0.00055 19.7 0.1 0.034 13.9 0.0 2.4 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_26 PF13659.1 KEZ41771.1 - 0.041 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GMP_PDE_delta PF05351.6 KEZ41771.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 GMP-PDE, delta subunit AAA_22 PF13401.1 KEZ41772.1 - 3e-05 24.1 4.9 0.0037 17.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 KEZ41772.1 - 6.7e-05 22.6 0.3 6.7e-05 22.6 0.2 2.5 3 1 0 3 3 3 1 NACHT domain Miro PF08477.8 KEZ41772.1 - 0.0011 19.4 0.0 0.0077 16.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 KEZ41772.1 - 0.006 16.0 0.9 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KEZ41772.1 - 0.0071 17.1 0.0 0.038 14.7 0.0 2.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEZ41772.1 - 0.032 14.5 0.2 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter cobW PF02492.14 KEZ41772.1 - 0.05 13.0 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KEZ41772.1 - 0.059 12.5 0.1 0.16 11.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEZ41772.1 - 0.07 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 KEZ41772.1 - 0.088 12.5 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KEZ41772.1 - 0.09 13.0 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KEZ41772.1 - 0.092 12.7 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF310 PF03750.8 KEZ41772.1 - 0.13 12.4 0.6 0.54 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF310) DUF87 PF01935.12 KEZ41772.1 - 0.49 10.1 4.1 11 5.8 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF342 PF03961.8 KEZ41772.1 - 0.61 8.4 3.4 1.1 7.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 KEZ41772.1 - 6.5 6.5 14.6 0.26 11.0 3.7 3.1 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugar_tr PF00083.19 KEZ41773.1 - 1.8e-73 247.6 15.1 2.2e-73 247.3 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41773.1 - 1.7e-28 99.3 48.5 6.6e-24 84.2 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ41774.1 - 3.9e-18 65.2 0.2 5.8e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldose_epim PF01263.15 KEZ41775.1 - 3.8e-57 193.6 0.0 4.9e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase GMC_oxred_C PF05199.8 KEZ41777.1 - 1.7e-30 106.2 0.0 2.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KEZ41777.1 - 7e-21 74.6 0.0 9.5e-18 64.3 0.1 2.7 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ41777.1 - 0.0037 16.1 0.2 0.0057 15.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ41777.1 - 0.0074 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ41777.1 - 0.0088 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ41777.1 - 0.025 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEZ41777.1 - 0.11 11.4 0.2 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KEZ41777.1 - 0.17 10.2 0.1 0.27 9.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.20 KEZ41778.1 - 6.5e-38 130.3 0.0 1.1e-37 129.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41778.1 - 1.9e-17 63.1 0.0 2.7e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KEZ41778.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA_30 PF13604.1 KEZ41779.1 - 0.0029 17.1 1.2 0.16 11.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain Sugar_tr PF00083.19 KEZ41780.1 - 3e-71 240.3 24.3 3.6e-71 240.0 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41780.1 - 7.7e-18 64.3 59.8 5.2e-17 61.5 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 KEZ41781.1 - 3.1e-154 513.7 0.0 3.5e-154 513.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEZ41781.1 - 8e-06 25.2 0.2 0.0051 16.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) PepSY PF03413.14 KEZ41781.1 - 0.058 14.0 0.4 9.6 6.9 0.0 2.8 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Fungal_trans_2 PF11951.3 KEZ41782.1 - 9e-17 60.7 0.2 5.2e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Alkyl_sulf_dimr PF14863.1 KEZ41782.1 - 0.045 13.9 0.1 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation ADH_N PF08240.7 KEZ41783.1 - 2.6e-24 85.0 2.9 3.5e-24 84.6 0.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ41783.1 - 1.9e-13 50.1 2.2 5.1e-12 45.4 0.6 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ILVD_EDD PF00920.16 KEZ41784.1 - 3.6e-197 655.9 1.9 4.2e-197 655.6 1.3 1.0 1 0 0 1 1 1 1 Dehydratase family NicO PF03824.11 KEZ41785.1 - 2.4e-53 181.2 20.0 2.7e-53 181.1 4.1 2.6 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 KEZ41785.1 - 0.11 11.3 3.7 0.047 12.5 0.6 1.8 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Methyltransf_23 PF13489.1 KEZ41786.1 - 5.9e-16 58.5 0.1 1.5e-15 57.2 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41786.1 - 3.1e-12 46.8 0.0 5.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41786.1 - 3e-09 36.6 0.0 2.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41786.1 - 5.3e-07 30.0 0.0 2.4e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41786.1 - 4.6e-06 27.1 0.0 9.3e-05 22.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ41786.1 - 0.00072 18.6 0.0 0.0085 15.1 0.0 2.3 2 1 1 3 3 3 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ41786.1 - 0.00096 19.4 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ41786.1 - 0.0066 15.5 0.0 0.042 12.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ41786.1 - 0.015 14.6 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.15 KEZ41786.1 - 0.057 12.4 0.0 0.26 10.3 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.7 KEZ41786.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.10 KEZ41786.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_16 PF10294.4 KEZ41786.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Transcrip_act PF04949.8 KEZ41787.1 - 0.042 13.4 1.1 0.069 12.7 0.8 1.3 1 0 0 1 1 1 0 Transcriptional activator Glyco_trans_4_4 PF13579.1 KEZ41788.1 - 0.045 13.8 0.7 1.7 8.7 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_hydro_6 PF01341.12 KEZ41789.1 - 5.1e-85 285.5 0.2 6e-85 285.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Aldo_ket_red PF00248.16 KEZ41790.1 - 2.5e-66 223.4 0.0 3e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SH3BGR PF04908.10 KEZ41791.1 - 8.2e-05 22.4 0.0 8.2e-05 22.4 0.0 2.7 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein CDC27 PF09507.5 KEZ41791.1 - 0.33 10.1 33.7 0.52 9.4 23.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Apt1 PF10351.4 KEZ41791.1 - 7.2 5.3 11.1 11 4.7 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Vfa1 PF08432.5 KEZ41791.1 - 7.3 6.5 23.1 0.42 10.6 11.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.8 KEZ41791.1 - 7.9 6.0 25.1 0.34 10.5 9.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region IBR PF01485.16 KEZ41792.1 - 6e-08 32.4 22.1 2.6e-05 24.0 0.7 2.9 3 0 0 3 3 3 2 IBR domain WD40 PF00400.27 KEZ41793.1 - 5.7e-96 311.3 22.7 7.6e-12 44.6 0.0 12.9 13 0 0 13 13 12 12 WD domain, G-beta repeat PD40 PF07676.7 KEZ41793.1 - 2.5e-19 68.5 6.1 4.4 7.0 0.0 11.8 12 0 0 12 12 12 5 WD40-like Beta Propeller Repeat NACHT PF05729.7 KEZ41793.1 - 1.8e-18 66.7 0.0 3.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.6 KEZ41793.1 - 5.7e-14 52.2 0.0 0.056 13.1 0.0 6.1 3 2 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KEZ41793.1 - 6.5e-14 50.9 14.7 0.12 10.5 0.0 9.8 4 2 6 11 11 11 5 Nucleoporin Nup120/160 Nbas_N PF15492.1 KEZ41793.1 - 1.8e-12 46.9 9.2 0.16 11.0 0.0 8.7 3 2 5 9 9 9 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 KEZ41793.1 - 5.8e-10 38.0 1.7 0.4 8.9 0.0 5.8 3 3 2 6 6 6 4 Cytochrome D1 heme domain PQQ_2 PF13360.1 KEZ41793.1 - 2.2e-09 37.1 15.7 0.03 13.7 0.0 5.3 4 2 0 4 4 4 3 PQQ-like domain Proteasome_A_N PF10584.4 KEZ41793.1 - 2e-07 30.2 4.3 10 5.5 0.0 8.7 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature SGL PF08450.7 KEZ41793.1 - 3.7e-07 29.7 0.9 0.2 11.0 0.0 5.6 1 1 3 5 5 5 2 SMP-30/Gluconolaconase/LRE-like region DUF1513 PF07433.6 KEZ41793.1 - 1.8e-06 27.0 8.8 0.14 11.0 0.2 6.0 3 3 1 5 5 5 2 Protein of unknown function (DUF1513) GSDH PF07995.6 KEZ41793.1 - 8.9e-06 25.0 0.1 7.1 5.6 0.0 6.4 5 2 1 6 6 6 1 Glucose / Sorbosone dehydrogenase DPPIV_N PF00930.16 KEZ41793.1 - 1.1e-05 24.2 0.0 4.6 5.7 0.0 6.4 2 2 1 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region TruB_C PF09142.6 KEZ41793.1 - 0.0061 16.1 7.7 34 4.1 0.1 8.0 9 1 1 10 10 10 0 tRNA Pseudouridine synthase II, C terminal IKI3 PF04762.7 KEZ41793.1 - 0.01 13.7 0.0 11 3.6 0.0 3.6 2 1 0 3 3 3 0 IKI3 family DUF642 PF04862.7 KEZ41793.1 - 0.012 15.2 0.1 0.57 9.8 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF642) DUF3748 PF12566.3 KEZ41793.1 - 0.058 13.3 0.0 32 4.4 0.0 4.3 3 2 1 4 4 4 0 Protein of unknown function (DUF3748) AAA_19 PF13245.1 KEZ41793.1 - 0.068 12.9 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF1258 PF06869.7 KEZ41793.1 - 0.091 11.8 0.1 2.1 7.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1258) Alg6_Alg8 PF03155.10 KEZ41794.1 - 3.1e-131 438.4 25.8 3.1e-82 276.9 7.3 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Herpes_gE PF02480.11 KEZ41795.1 - 0.012 13.9 0.0 0.017 13.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3481 PF11980.3 KEZ41795.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) SURF4 PF02077.10 KEZ41797.1 - 4.8e-95 317.9 9.3 5.5e-95 317.7 6.5 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 KEZ41797.1 - 2.1 8.5 16.5 1.8 8.7 1.2 2.8 2 1 0 2 2 2 0 Type IV leader peptidase family DUF1129 PF06570.6 KEZ41797.1 - 4.6 6.4 6.9 4.6 6.5 3.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Halogen_Hydrol PF10112.4 KEZ41797.1 - 9.6 5.5 7.8 4.7 6.5 0.7 2.7 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RRM_1 PF00076.17 KEZ41798.1 - 2.6e-14 52.6 0.1 4.3e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41798.1 - 1.6e-10 40.7 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41798.1 - 3.1e-09 36.5 0.2 4.7e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_6 PF13912.1 KEZ41799.1 - 0.076 12.9 0.5 0.45 10.5 0.4 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KEZ41799.1 - 0.13 12.6 0.0 0.13 12.6 0.0 6.7 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ41799.1 - 4.8 7.7 32.0 4.7 7.7 0.3 6.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type Choline_kinase PF01633.15 KEZ41800.1 - 7.4e-51 172.7 0.0 2.9e-50 170.8 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 KEZ41800.1 - 1.1e-09 38.3 1.1 1.6e-09 37.9 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family NPR3 PF03666.8 KEZ41801.1 - 2.2e-127 425.3 0.2 2.2e-127 425.3 0.1 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Got1 PF04178.7 KEZ41802.1 - 1.9e-31 108.6 19.2 2.4e-31 108.2 13.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KEZ41802.1 - 0.0029 16.5 0.0 0.0051 15.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M50 Claudin_2 PF13903.1 KEZ41802.1 - 0.065 12.9 12.8 0.055 13.1 6.6 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 KEZ41802.1 - 1.4 8.5 10.6 0.56 9.8 5.2 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.4 KEZ41802.1 - 4.7 5.6 6.1 14 4.0 4.2 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) La PF05383.12 KEZ41804.1 - 7.8e-15 54.4 0.0 1.4e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 La domain Prp31_C PF09785.4 KEZ41805.1 - 1.8e-43 147.9 1.6 4.5e-43 146.6 1.1 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 KEZ41805.1 - 2.9e-41 140.2 0.1 5.2e-41 139.4 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KEZ41805.1 - 2.1e-21 75.4 0.1 7.6e-21 73.6 0.0 1.9 2 0 0 2 2 2 1 NOSIC (NUC001) domain Sugar_tr PF00083.19 KEZ41807.1 - 1.2e-31 109.7 31.9 2.6e-20 72.4 5.6 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41807.1 - 2.8e-22 78.9 25.3 9.3e-16 57.4 8.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.5 KEZ41807.1 - 0.023 14.3 1.7 0.023 14.3 1.2 3.8 4 1 0 4 4 4 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4131 PF13567.1 KEZ41807.1 - 0.089 12.1 8.1 8.3 5.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Fungal_trans PF04082.13 KEZ41808.1 - 1.1e-21 76.8 0.1 2.4e-21 75.7 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41808.1 - 1.4e-08 34.4 8.6 2.8e-08 33.5 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fra10Ac1 PF09725.4 KEZ41808.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 WD40 PF00400.27 KEZ41809.1 - 4.1e-26 89.8 9.8 6.2e-07 29.0 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KEZ41809.1 - 0.0015 16.7 0.5 0.024 12.7 0.1 2.6 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KEZ41809.1 - 0.016 13.5 0.0 0.53 8.5 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.6 KEZ41809.1 - 0.054 13.1 0.2 4.7 6.8 0.0 3.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A RIC1 PF07064.8 KEZ41811.1 - 1.1e-87 293.7 1.2 2.1e-87 292.8 0.8 1.4 1 0 0 1 1 1 1 RIC1 CK_II_beta PF01214.13 KEZ41811.1 - 3.3e-54 183.2 3.5 1.8e-52 177.5 2.4 2.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit WD40 PF00400.27 KEZ41811.1 - 2.4e-05 24.0 0.1 3.6 7.6 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PAP2 PF01569.16 KEZ41812.1 - 5.9e-21 74.4 1.7 2.1e-20 72.7 0.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_L2_C PF03947.13 KEZ41813.1 - 3.7e-44 149.6 2.5 2.2e-43 147.1 1.8 2.2 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KEZ41813.1 - 9.3e-24 83.2 0.3 2.1e-23 82.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 KEZ41814.1 - 6.3e-45 151.8 0.1 1.4e-44 150.7 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEZ41814.1 - 1.4e-32 112.0 0.0 2.5e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ion_trans PF00520.26 KEZ41815.1 - 3.2e-80 268.1 91.6 3.1e-27 95.1 5.2 6.2 5 1 1 6 6 6 5 Ion transport protein MutS_V PF00488.16 KEZ41815.1 - 1.3e-49 168.7 0.0 2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V JSRP PF15312.1 KEZ41815.1 - 0.02 14.8 0.1 0.057 13.3 0.1 1.7 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein PKD_channel PF08016.7 KEZ41815.1 - 0.026 12.9 34.3 0.025 13.0 3.8 5.6 4 1 1 5 5 5 0 Polycystin cation channel AAA_22 PF13401.1 KEZ41815.1 - 0.13 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HMG_box PF00505.14 KEZ41816.1 - 1.4e-12 47.6 1.1 1.4e-12 47.6 0.8 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEZ41816.1 - 0.00058 20.1 1.7 0.00059 20.1 0.2 1.8 2 0 0 2 2 2 1 HMG-box domain MAT_Alpha1 PF04769.7 KEZ41816.1 - 0.024 13.9 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 PHD PF00628.24 KEZ41817.1 - 4.8e-09 35.7 7.7 9.7e-09 34.7 5.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KEZ41817.1 - 0.014 14.7 4.6 0.031 13.5 3.2 1.6 1 0 0 1 1 1 0 PHD-finger AAA_23 PF13476.1 KEZ41817.1 - 2.1 8.6 10.1 3.9 7.7 7.0 1.5 1 0 0 1 1 1 0 AAA domain UAA PF08449.6 KEZ41818.1 - 1.3e-90 303.4 4.0 1.7e-90 303.0 2.8 1.1 1 0 0 1 1 1 1 UAA transporter family WD40 PF00400.27 KEZ41818.1 - 8.1e-11 41.3 2.8 1.7 8.6 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nuc_sug_transp PF04142.10 KEZ41818.1 - 1.7e-05 24.0 0.1 3.7e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KEZ41818.1 - 0.012 15.7 13.6 0.14 12.3 1.3 3.0 2 1 0 2 2 2 0 Multidrug resistance efflux transporter TPT PF03151.11 KEZ41818.1 - 0.015 14.9 0.7 0.015 14.9 0.5 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family UPF0546 PF10639.4 KEZ41818.1 - 0.21 11.3 3.2 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 EamA PF00892.15 KEZ41818.1 - 0.35 10.9 16.4 0.72 9.8 2.5 2.5 2 0 0 2 2 2 0 EamA-like transporter family A_deaminase PF00962.17 KEZ41819.1 - 6.4e-112 373.7 0.1 8.1e-112 373.3 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_1 PF00018.23 KEZ41820.1 - 1.1e-36 123.8 5.1 8.4e-14 50.6 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KEZ41820.1 - 1.1e-34 117.8 0.0 2e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 KEZ41820.1 - 4.7e-33 112.5 7.1 9.7e-13 47.4 0.2 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 KEZ41820.1 - 6.2e-23 80.0 0.1 6e-08 32.0 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 KEZ41820.1 - 0.0046 17.1 4.2 1 9.5 0.2 3.7 4 0 0 4 4 4 2 Bacterial SH3 domain TRAM_LAG1_CLN8 PF03798.11 KEZ41821.1 - 2.2e-47 161.1 15.0 2.2e-47 161.1 10.4 1.5 2 0 0 2 2 2 1 TLC domain Mito_carr PF00153.22 KEZ41822.1 - 1.9e-56 187.7 0.9 9.4e-20 70.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CHAT PF12770.2 KEZ41823.1 - 0.13 11.4 2.3 0.23 10.5 1.6 1.5 1 0 0 1 1 1 0 CHAT domain Borrelia_P83 PF05262.6 KEZ41823.1 - 9.9 4.2 24.7 12 3.9 17.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Prefoldin_2 PF01920.15 KEZ41824.1 - 1.3e-16 60.2 2.1 1.7e-16 59.8 1.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.3 KEZ41824.1 - 0.00039 20.1 0.2 0.00039 20.1 0.1 2.1 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.7 KEZ41824.1 - 0.014 15.7 1.4 0.1 13.0 0.1 2.2 2 0 0 2 2 2 0 SlyX ADIP PF11559.3 KEZ41824.1 - 0.024 14.5 6.2 0.69 9.8 1.1 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PspA_IM30 PF04012.7 KEZ41824.1 - 0.033 13.5 3.6 0.08 12.2 2.5 1.5 1 1 0 1 1 1 0 PspA/IM30 family DUF4265 PF14085.1 KEZ41824.1 - 0.034 13.9 0.0 0.067 12.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4265) DUF4200 PF13863.1 KEZ41824.1 - 0.036 14.0 5.5 0.079 12.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) USP8_interact PF08941.5 KEZ41824.1 - 0.06 12.6 0.8 0.091 12.0 0.3 1.5 1 1 0 1 1 1 0 USP8 interacting Striatin PF08232.7 KEZ41824.1 - 0.063 13.5 3.6 0.32 11.2 0.2 2.1 2 0 0 2 2 2 0 Striatin family Radical_SAM PF04055.16 KEZ41824.1 - 0.091 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Radical SAM superfamily IncA PF04156.9 KEZ41824.1 - 0.12 11.9 3.8 0.26 10.8 2.7 1.5 1 1 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 KEZ41824.1 - 0.14 12.2 3.6 4 7.5 0.7 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Sec2p PF06428.6 KEZ41824.1 - 0.14 11.9 2.7 1.6 8.6 0.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CENP-Q PF13094.1 KEZ41824.1 - 0.17 11.8 6.7 3 7.8 0.0 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4618 PF15397.1 KEZ41824.1 - 0.19 11.0 2.0 7.6 5.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Tropomyosin PF00261.15 KEZ41824.1 - 0.21 10.6 3.8 3.3 6.7 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin DUF2968 PF11180.3 KEZ41824.1 - 0.27 10.6 3.0 1.6 8.0 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 KEZ41824.1 - 0.73 9.6 7.2 2.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Swi5 PF07061.6 KEZ41824.1 - 0.75 9.6 3.5 7.5 6.4 0.9 2.1 2 0 0 2 2 2 0 Swi5 ATG16 PF08614.6 KEZ41824.1 - 0.82 9.4 4.9 2.4 7.9 1.4 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF16 PF01519.11 KEZ41824.1 - 0.95 9.7 4.3 9.2 6.5 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 TMF_DNA_bd PF12329.3 KEZ41824.1 - 1 9.2 10.0 4.7 7.0 0.1 2.7 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HrpB7 PF09486.5 KEZ41824.1 - 1.5 8.7 5.7 0.71 9.7 2.0 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) OEP PF02321.13 KEZ41824.1 - 3.6 7.1 7.9 11 5.5 4.0 1.9 2 0 0 2 2 2 0 Outer membrane efflux protein TMF_TATA_bd PF12325.3 KEZ41825.1 - 2.9e-37 127.0 12.1 2.9e-37 127.0 8.4 5.5 3 1 2 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KEZ41825.1 - 4.7e-15 55.1 7.0 4.7e-15 55.1 4.8 7.4 6 3 2 8 8 8 2 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KEZ41825.1 - 0.46 9.6 22.4 0.039 13.1 2.0 3.5 3 1 1 4 4 4 0 Reovirus sigma C capsid protein GAS PF13851.1 KEZ41825.1 - 1.1 8.3 48.2 0.24 10.5 4.0 5.1 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding Tweety PF04906.8 KEZ41825.1 - 1.7 7.0 6.7 0.36 9.1 0.2 2.4 2 0 0 2 2 2 0 Tweety Phage_GP20 PF06810.6 KEZ41825.1 - 4.6 6.6 43.6 0.99 8.8 3.9 6.3 3 3 2 6 6 6 0 Phage minor structural protein GP20 DUF948 PF06103.6 KEZ41825.1 - 5.8 6.8 12.5 21 5.0 0.1 5.6 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.2 KEZ41826.1 - 1.2e-34 118.5 1.6 2.5e-13 50.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEZ41826.1 - 3.4e-33 112.9 3.2 4.6e-11 42.5 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 KEZ41826.1 - 1.4e-31 106.7 4.2 3.3e-05 23.4 0.2 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KEZ41826.1 - 2.5e-30 104.2 5.5 5.4e-11 42.6 0.1 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ41826.1 - 2.4e-26 89.1 0.5 0.00063 19.7 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat WD40 PF00400.27 KEZ41827.1 - 2.1e-53 176.3 15.5 1.7e-10 40.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEZ41827.1 - 0.00058 18.1 4.4 1.8 6.5 0.1 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KEZ41827.1 - 0.0076 15.7 0.3 3.1 7.1 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain AAA PF00004.24 KEZ41828.1 - 1.3e-14 54.5 0.0 3.6e-14 53.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ41828.1 - 1.2e-10 41.7 0.1 6.9e-10 39.2 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEZ41828.1 - 5.2e-08 33.1 0.0 1.4e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KEZ41828.1 - 7.5e-05 22.5 0.1 0.00076 19.2 0.0 2.3 2 1 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 KEZ41828.1 - 0.00032 20.4 0.1 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KEZ41828.1 - 0.0015 18.1 0.0 0.0033 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ41828.1 - 0.0033 18.2 0.0 0.014 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 KEZ41828.1 - 0.0082 15.6 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) NACHT PF05729.7 KEZ41828.1 - 0.0091 15.6 0.0 0.029 14.0 0.0 1.9 1 1 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 KEZ41828.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KEZ41828.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain End_beta_barrel PF12195.3 KEZ41828.1 - 0.03 14.0 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase RNA_helicase PF00910.17 KEZ41828.1 - 0.035 14.2 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.1 KEZ41828.1 - 0.042 12.5 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEZ41828.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEZ41828.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase ResIII PF04851.10 KEZ41828.1 - 0.069 12.9 0.1 1.3 8.7 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KEZ41828.1 - 0.085 12.1 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_3 PF07726.6 KEZ41828.1 - 0.098 12.2 0.1 1.5 8.4 0.0 2.5 2 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 KEZ41828.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ORC5_C PF14630.1 KEZ41828.1 - 0.16 11.3 0.6 16 4.8 0.4 2.2 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Baculo_11_kDa PF06143.6 KEZ41828.1 - 0.24 10.7 0.7 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Baculovirus 11 kDa family Cpn60_TCP1 PF00118.19 KEZ41829.1 - 4.3e-161 536.8 0.1 4.9e-161 536.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.17 KEZ41830.1 - 2.7e-33 115.2 0.1 5.3e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KEZ41830.1 - 2.4e-05 23.8 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.17 KEZ41831.1 - 1.6e-189 630.0 0.7 1.8e-189 629.8 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEZ41831.1 - 0.094 11.9 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TRF PF08558.5 KEZ41832.1 - 7.6e-19 68.0 0.8 1.3e-18 67.2 0.6 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 KEZ41832.1 - 5.7e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEZ41832.1 - 0.017 15.1 0.1 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain bZIP_1 PF00170.16 KEZ41834.1 - 9.4e-08 31.9 13.5 1.8e-07 30.9 9.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ41834.1 - 0.035 13.9 18.5 0.086 12.6 11.7 2.1 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 KEZ41834.1 - 0.044 14.0 14.3 0.052 13.8 9.3 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor Glutaredoxin2_C PF04399.8 KEZ41834.1 - 0.051 13.1 1.4 0.09 12.3 0.9 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF972 PF06156.8 KEZ41834.1 - 0.072 13.4 0.4 0.072 13.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) BTV_NS2 PF04514.7 KEZ41834.1 - 0.7 8.7 4.9 0.9 8.3 3.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4407 PF14362.1 KEZ41834.1 - 2.2 7.1 10.9 3.2 6.6 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Dad1 PF08649.5 KEZ41835.1 - 1.6e-24 85.3 0.9 2.1e-24 84.9 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Ras PF00071.17 KEZ41836.1 - 7.9e-46 155.3 0.0 1.1e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ41836.1 - 1.8e-10 41.3 0.0 3.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ41836.1 - 5.1e-05 22.5 0.0 0.00012 21.3 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Skp1_POZ PF03931.10 KEZ41837.1 - 9e-11 41.7 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.8 KEZ41838.1 - 6.8e-49 165.4 0.0 1.2e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KEZ41838.1 - 2.6e-07 30.2 0.6 3.9e-07 29.6 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PRMT5 PF05185.11 KEZ41839.1 - 2.4e-161 537.6 0.0 3e-161 537.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 KEZ41840.1 - 2.9e-25 88.2 0.1 2.6e-24 85.2 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEZ41840.1 - 1.3e-22 79.6 0.1 3e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEZ41840.1 - 7.5e-11 41.7 0.0 1.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ41840.1 - 2.9e-07 30.1 0.3 6.2e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEZ41840.1 - 7.1e-06 26.1 0.1 2.9e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KEZ41840.1 - 0.00011 21.7 0.1 0.00036 20.0 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 KEZ41840.1 - 0.0013 17.6 0.0 0.003 16.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 KEZ41840.1 - 0.0082 15.9 0.2 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 KEZ41840.1 - 0.012 15.4 0.1 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Response_reg PF00072.19 KEZ41840.1 - 0.15 12.0 0.8 0.8 9.7 0.2 2.2 2 0 0 2 2 2 0 Response regulator receiver domain AAA_30 PF13604.1 KEZ41840.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.23 KEZ41842.1 - 3.3e-85 286.0 0.0 3.9e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Gly_transf_sug PF04488.10 KEZ41843.1 - 1.6e-16 60.5 0.0 2.4e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Band_7 PF01145.20 KEZ41844.1 - 2.7e-26 92.5 1.3 4.3e-26 91.9 0.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family APC10 PF03256.11 KEZ41845.1 - 4.5e-43 147.0 0.0 6.8e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Ank_2 PF12796.2 KEZ41846.1 - 3.1e-44 149.2 2.2 6.9e-13 48.7 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ41846.1 - 5.5e-30 103.1 1.0 3.5e-09 36.9 0.0 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 KEZ41846.1 - 6.2e-30 101.5 4.4 5.2e-05 22.8 0.0 7.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KEZ41846.1 - 4.4e-28 96.6 2.0 1.9e-09 37.4 0.1 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ41846.1 - 1.4e-25 86.8 1.1 5e-06 26.2 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat AAA_16 PF13191.1 KEZ41846.1 - 0.024 14.6 0.0 0.2 11.6 0.0 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KEZ41846.1 - 0.059 13.5 0.0 0.54 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain PD-C2-AF1 PF09310.5 KEZ41846.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 DUF3425 PF11905.3 KEZ41847.1 - 4.5e-32 110.7 4.8 8.7e-32 109.8 3.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KEZ41847.1 - 0.09 12.7 2.1 0.27 11.2 1.3 1.8 1 1 1 2 2 2 0 bZIP transcription factor DUF1537 PF07005.6 KEZ41847.1 - 0.14 11.8 5.2 0.21 11.2 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 DUF4519 PF15012.1 KEZ41848.1 - 0.089 12.7 3.3 0.15 11.9 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) E1-E2_ATPase PF00122.15 KEZ41849.1 - 1.1e-61 207.8 7.9 2.4e-61 206.7 5.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ41849.1 - 7.5e-23 82.0 0.0 1.6e-22 81.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ41849.1 - 4.4e-13 49.8 0.0 1.2e-12 48.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ41849.1 - 9.2e-11 41.0 0.0 2.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEZ41849.1 - 0.0014 18.2 0.1 0.0028 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ41849.1 - 0.036 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Phage_fiber_C PF06820.7 KEZ41849.1 - 0.11 12.7 0.5 0.34 11.0 0.1 2.1 2 0 0 2 2 2 0 Putative prophage tail fibre C-terminus Mito_carr PF00153.22 KEZ41850.1 - 1.5e-29 101.4 6.6 1.6e-13 50.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 KEZ41851.1 - 7.7e-102 340.6 0.0 9.2e-102 340.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 KEZ41851.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone XH PF03469.9 KEZ41851.1 - 0.086 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 XH domain RRM_1 PF00076.17 KEZ41852.1 - 9.3e-07 28.3 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ41852.1 - 1.8e-06 27.6 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ41852.1 - 6.5e-05 22.8 0.1 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KEZ41852.1 - 0.00035 20.7 0.3 0.0016 18.6 0.2 2.0 1 1 0 1 1 1 1 RNA polymerase II-binding domain. WD40 PF00400.27 KEZ41853.1 - 1.2e-05 24.9 9.5 0.56 10.1 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Nop PF01798.13 KEZ41855.1 - 1.9e-51 173.3 1.9 1.1e-50 170.8 1.3 2.3 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KEZ41855.1 - 9e-24 83.0 0.0 1.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KEZ41855.1 - 8.8e-17 61.0 0.1 8.8e-17 61.0 0.0 3.2 2 1 0 2 2 2 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.11 KEZ41856.1 - 1.5e-109 366.1 0.0 1.7e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.17 KEZ41857.1 - 9.4e-18 63.7 0.6 2.5e-17 62.3 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 KEZ41858.1 - 4.2e-45 153.5 0.0 7e-24 84.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 VTC PF09359.5 KEZ41859.1 - 9.7e-92 306.9 0.0 9.7e-92 306.9 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KEZ41859.1 - 9.9e-20 71.4 16.1 7.3e-10 39.0 1.0 3.4 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 KEZ41859.1 - 2.1e-09 37.4 4.3 2.1e-09 37.4 3.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cob_adeno_trans PF01923.13 KEZ41859.1 - 0.0021 17.8 0.1 0.92 9.2 0.0 2.4 2 0 0 2 2 2 2 Cobalamin adenosyltransferase MgtE PF01769.11 KEZ41859.1 - 0.0076 16.5 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 Divalent cation transporter AAA_5 PF07728.9 KEZ41860.1 - 5.1e-12 45.7 0.0 1.3e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEZ41860.1 - 7.9e-11 42.1 0.0 3.2e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEZ41860.1 - 9.8e-07 29.0 0.0 2.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KEZ41860.1 - 0.00013 21.1 0.0 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEZ41860.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KEZ41860.1 - 0.0049 16.9 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 KEZ41860.1 - 0.006 16.5 0.0 0.2 11.6 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain Ank PF00023.25 KEZ41860.1 - 0.009 15.7 0.0 0.34 10.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Torsin PF06309.6 KEZ41860.1 - 0.04 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_17 PF13207.1 KEZ41860.1 - 0.083 13.7 0.0 0.39 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ank_4 PF13637.1 KEZ41860.1 - 0.11 13.0 0.0 0.56 10.7 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Zeta_toxin PF06414.7 KEZ41860.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Nic96 PF04097.9 KEZ41862.1 - 1.5e-203 677.3 0.0 1.9e-203 677.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 KEZ41862.1 - 3.4e-10 40.1 69.1 5.5e-06 26.5 17.4 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region FGGY_C PF02782.11 KEZ41863.1 - 4e-52 176.7 0.2 6.9e-52 175.9 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEZ41863.1 - 8.6e-21 74.3 0.4 1e-16 61.0 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain UPF0075 PF03702.9 KEZ41863.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Myb_DNA-binding PF00249.26 KEZ41864.1 - 3.9e-09 36.4 0.0 7.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEZ41864.1 - 0.011 15.7 0.3 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain DS PF01916.12 KEZ41865.1 - 5.4e-83 278.5 3.1 7.7e-40 136.8 0.6 3.2 1 1 2 3 3 3 3 Deoxyhypusine synthase APH PF01636.18 KEZ41865.1 - 1.4e-07 31.5 0.3 2.3e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ41865.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family gpW PF02831.10 KEZ41865.1 - 0.17 11.4 0.2 1.7 8.2 0.0 2.5 3 0 0 3 3 3 0 gpW HSF_DNA-bind PF00447.12 KEZ41866.1 - 1.3e-28 99.1 3.9 2e-28 98.6 0.2 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding DUF373 PF04123.8 KEZ41866.1 - 0.28 10.1 0.0 0.4 9.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) V_ATPase_I PF01496.14 KEZ41866.1 - 0.34 8.7 1.8 0.48 8.2 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Clr5 PF14420.1 KEZ41866.1 - 1.1 9.2 3.7 1.2 9.1 1.0 2.2 2 1 1 3 3 3 0 Clr5 domain APG6 PF04111.7 KEZ41866.1 - 1.2 8.1 10.1 2.8 6.9 7.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC37_N PF03234.9 KEZ41866.1 - 6.8 6.9 12.9 0.94 9.7 5.8 1.8 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Pro_isomerase PF00160.16 KEZ41867.1 - 3e-45 154.2 0.0 3.4e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 KEZ41868.1 - 1.1e-12 48.2 0.0 2e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain ATP-grasp_2 PF08442.5 KEZ41870.1 - 3.1e-77 258.5 0.4 5.1e-77 257.8 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KEZ41870.1 - 8.6e-26 90.3 0.2 2.1e-25 89.1 0.2 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KEZ41870.1 - 1.1e-09 37.8 0.1 2.3e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KEZ41870.1 - 0.00021 21.0 0.0 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KEZ41870.1 - 0.0014 18.2 0.5 0.0062 16.1 0.1 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 KEZ41870.1 - 0.037 13.4 0.0 0.36 10.2 0.0 2.4 2 1 1 3 3 3 0 RimK-like ATP-grasp domain APH PF01636.18 KEZ41871.1 - 0.011 15.4 0.9 0.011 15.4 0.6 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF2435 PF10363.4 KEZ41872.1 - 9.1e-17 60.7 4.4 1.2e-14 53.9 0.0 4.3 3 1 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KEZ41872.1 - 2.7e-11 42.6 1.3 4.9e-11 41.8 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) Thr_synth_N PF14821.1 KEZ41873.1 - 1.2e-28 98.9 0.0 2.5e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 KEZ41873.1 - 3.3e-19 69.2 0.0 9.2e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MARVEL PF01284.18 KEZ41874.1 - 6.2e-07 29.3 13.2 7.6e-07 29.0 9.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.15 KEZ41875.1 - 1.5e-150 500.7 0.0 1.7e-150 500.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEZ41875.1 - 6.4e-15 55.0 0.3 3.5e-14 52.6 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KEZ41875.1 - 1.2e-09 37.6 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEZ41875.1 - 1.7e-08 33.6 0.3 3.6e-08 32.5 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEZ41875.1 - 1.2e-07 31.2 0.0 2.3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KEZ41875.1 - 0.0052 15.1 0.0 0.007 14.7 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 KEZ41875.1 - 0.0054 15.2 0.0 0.0083 14.6 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 KEZ41875.1 - 0.03 13.0 0.0 0.057 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF2235 PF09994.4 KEZ41876.1 - 1.6e-23 83.5 0.1 3.7e-23 82.2 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Osmo_CC PF08946.5 KEZ41877.1 - 0.044 13.8 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Ank_2 PF12796.2 KEZ41879.1 - 4.4e-17 62.1 0.1 4.7e-11 42.8 0.0 3.6 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ41879.1 - 6e-13 48.9 0.3 1.1e-06 28.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KEZ41879.1 - 3.3e-11 42.4 7.9 0.00012 21.6 0.1 5.4 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KEZ41879.1 - 7.7e-07 28.7 2.2 0.0025 17.8 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 KEZ41879.1 - 0.0003 20.9 5.5 0.0029 17.8 0.1 4.4 3 2 1 4 4 4 1 Ankyrin repeats (many copies) DUF3867 PF12983.2 KEZ41879.1 - 0.0054 16.7 0.1 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3867) WD40 PF00400.27 KEZ41880.1 - 4.4e-82 267.3 10.2 2.7e-14 52.3 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KEZ41880.1 - 9e-09 34.0 8.0 0.013 13.6 0.0 5.6 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEZ41880.1 - 1.7e-06 27.0 5.6 1.6 7.3 0.0 5.4 1 1 5 6 6 6 3 Nup133 N terminal like PQQ_2 PF13360.1 KEZ41880.1 - 7.5e-05 22.3 1.6 0.0009 18.7 1.1 2.8 1 1 1 2 2 2 2 PQQ-like domain NACHT PF05729.7 KEZ41880.1 - 0.00088 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Nbas_N PF15492.1 KEZ41880.1 - 0.0017 17.5 3.3 12 4.8 0.0 4.7 1 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Pectate_lyase22 PF14583.1 KEZ41880.1 - 0.03 12.7 0.0 0.95 7.8 0.0 2.3 2 0 0 2 2 2 0 Oligogalacturonate lyase HTH_20 PF12840.2 KEZ41880.1 - 0.069 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Me-amine-dh_H PF06433.6 KEZ41880.1 - 0.087 11.4 0.0 1.2 7.7 0.0 2.8 3 1 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) Proteasome_A_N PF10584.4 KEZ41880.1 - 0.14 11.5 4.4 14 5.1 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature GSDH PF07995.6 KEZ41880.1 - 0.14 11.1 0.0 24 3.8 0.0 2.9 1 1 2 4 4 4 0 Glucose / Sorbosone dehydrogenase PD40 PF07676.7 KEZ41880.1 - 4.2 7.1 11.2 73 3.1 0.0 5.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 KEZ41881.1 - 2.1e-30 105.6 30.4 3.7e-30 104.8 20.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HgmA PF04209.8 KEZ41882.1 - 1.7e-175 583.5 0.0 2.5e-175 582.9 0.0 1.2 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.13 KEZ41882.1 - 2.7e-13 49.4 0.4 4.6e-13 48.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KEZ41883.1 - 2.9e-52 177.7 0.0 2.5e-47 161.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAA_hydrolase PF01557.13 KEZ41884.1 - 9.9e-29 100.3 0.0 1.9e-28 99.4 0.0 1.4 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KEZ41884.1 - 4.5e-27 94.1 0.1 2.1e-26 91.9 0.0 2.1 2 1 0 2 2 2 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.11 KEZ41885.1 - 8e-09 34.6 35.1 6.4e-08 31.6 24.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEZ41885.1 - 2.7e-07 30.2 6.5 6.8e-07 28.9 4.5 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 KEZ41885.1 - 0.036 12.6 19.6 0.38 9.2 8.3 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter TauD PF02668.11 KEZ41886.1 - 9.6e-33 113.9 0.0 1.3e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEZ41886.1 - 0.057 12.3 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 CsiD HpcH_HpaI PF03328.9 KEZ41888.1 - 6.1e-25 87.4 0.0 8.2e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family AA_permease_2 PF13520.1 KEZ41889.1 - 8.6e-59 199.1 28.7 1e-58 198.8 19.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ41889.1 - 2.6e-21 75.5 29.2 7.5e-21 74.0 16.2 2.2 2 0 0 2 2 2 2 Amino acid permease DUF3176 PF11374.3 KEZ41890.1 - 3.2e-07 30.2 2.0 3.2e-07 30.2 1.4 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3176) Methyltransf_23 PF13489.1 KEZ41891.1 - 2.4e-16 59.8 0.0 4.1e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41891.1 - 4.3e-08 33.5 0.0 6e-07 29.8 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ41891.1 - 0.00015 20.9 0.0 0.0012 18.0 0.0 2.2 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEZ41891.1 - 0.00055 20.3 0.0 0.0037 17.7 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41891.1 - 0.00082 18.9 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.7 KEZ41891.1 - 0.017 14.4 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KEZ41891.1 - 0.018 15.6 0.2 0.77 10.3 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain F-box PF00646.28 KEZ41892.1 - 1.9e-06 27.3 0.1 4.6e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEZ41892.1 - 8.5e-05 22.2 0.1 0.00019 21.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KEZ41892.1 - 0.0095 15.6 0.2 0.033 13.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like domain FUSC_2 PF13515.1 KEZ41893.1 - 7.2e-17 61.4 12.1 1.4e-16 60.5 8.4 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF2422 PF10337.4 KEZ41893.1 - 1.9e-15 56.6 0.0 1.9e-15 56.6 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KEZ41893.1 - 3.4e-07 30.1 0.0 2.6e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KEZ41893.1 - 1.6e-06 27.0 10.1 0.02 13.6 0.0 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF939 PF06081.6 KEZ41893.1 - 0.26 11.1 7.5 0.71 9.7 5.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) ECH PF00378.15 KEZ41894.1 - 3.9e-37 127.6 0.0 5.1e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Acyl_transf_3 PF01757.17 KEZ41895.1 - 3.1e-26 92.0 21.0 4.4e-26 91.5 14.6 1.3 1 0 0 1 1 1 1 Acyltransferase family Abhydrolase_2 PF02230.11 KEZ41896.1 - 9.3e-22 77.5 0.0 4.9e-21 75.1 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KEZ41896.1 - 6.2e-06 26.2 1.7 0.0016 18.3 0.8 2.2 1 1 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ41896.1 - 0.00011 21.4 0.3 0.0084 15.3 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ41896.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ41896.1 - 0.006 16.1 0.1 2.5 7.6 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.9 KEZ41896.1 - 0.0073 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase ADH_N PF08240.7 KEZ41897.1 - 2.1e-29 101.4 0.4 4.4e-29 100.4 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ41897.1 - 3.9e-24 84.6 0.9 6.4e-24 83.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ41897.1 - 0.0015 17.7 0.1 0.0061 15.7 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glucokinase PF02685.11 KEZ41897.1 - 0.032 13.0 0.2 0.047 12.4 0.2 1.3 1 0 0 1 1 1 0 Glucokinase Pkinase PF00069.20 KEZ41898.1 - 6.6e-16 58.2 0.0 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41898.1 - 8.3e-06 25.0 0.0 1.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NRN1 PF15056.1 KEZ41899.1 - 0.021 14.7 0.3 0.22 11.4 0.0 2.2 1 1 1 2 2 2 0 Neuritin protein family HTH_29 PF13551.1 KEZ41901.1 - 1.8e-07 31.2 0.3 7.3e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.1 KEZ41901.1 - 0.0017 17.9 1.8 0.011 15.3 0.1 2.6 3 1 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 KEZ41901.1 - 0.0083 15.6 1.6 0.11 12.0 0.1 2.5 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 KEZ41901.1 - 0.02 14.3 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.1 KEZ41901.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Bac_rhodopsin PF01036.13 KEZ41902.1 - 4.8e-29 101.2 30.7 5.9e-29 100.9 21.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4231 PF14015.1 KEZ41902.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) E1-E2_ATPase PF00122.15 KEZ41904.1 - 4.7e-54 182.8 3.3 8.1e-54 182.0 2.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ41904.1 - 2.1e-39 134.9 4.9 2.1e-39 134.9 3.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ41904.1 - 1.2e-24 87.8 0.0 5.4e-24 85.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ41904.1 - 4.2e-17 61.8 0.0 1.3e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ41904.1 - 2.6e-12 47.3 0.0 6.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ41904.1 - 1.8e-08 33.6 1.9 1.1e-07 31.2 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEZ41904.1 - 9.1e-07 28.7 0.4 5e-05 23.0 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.3 KEZ41904.1 - 0.14 11.7 3.9 3.3 7.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Viral_Beta_CD PF04530.7 KEZ41904.1 - 0.17 12.0 0.1 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family EXS PF03124.9 KEZ41904.1 - 0.62 9.0 5.6 1.4 7.8 0.1 2.8 3 0 0 3 3 3 0 EXS family MFS_1 PF07690.11 KEZ41905.1 - 1.4e-26 93.0 35.6 1.4e-26 93.0 24.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KEZ41905.1 - 1.6 8.7 12.4 0.54 10.3 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Fungal_trans_2 PF11951.3 KEZ41906.1 - 2.6e-47 161.2 0.0 3.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41906.1 - 7.6e-06 25.7 10.6 1.5e-05 24.7 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.9 KEZ41907.1 - 1.7e-174 580.9 0.0 2.3e-174 580.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KEZ41907.1 - 4.7e-95 318.0 0.1 1.8e-93 312.8 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEZ41907.1 - 1.6e-52 177.5 3.6 5e-52 175.9 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Chitin_bind_1 PF00187.14 KEZ41908.1 - 9.8e-08 31.8 48.0 4.5e-05 23.3 14.3 3.4 2 1 2 4 4 4 2 Chitin recognition protein SKG6 PF08693.5 KEZ41908.1 - 3.7e-07 29.3 0.0 7.8e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KEZ41908.1 - 0.0016 18.0 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.6 KEZ41908.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.1 KEZ41908.1 - 0.03 13.7 0.1 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1517 PF07466.6 KEZ41908.1 - 0.081 11.8 0.2 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Lamp PF01299.12 KEZ41908.1 - 0.12 11.4 1.0 0.19 10.8 0.0 1.7 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) DUF1510 PF07423.6 KEZ41908.1 - 0.43 9.9 6.0 1.5 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) FAD_binding_4 PF01565.18 KEZ41909.1 - 4.5e-19 68.3 1.8 8.4e-19 67.4 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ41909.1 - 1.6e-10 40.6 0.1 3.6e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KEZ41909.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding LysM PF01476.15 KEZ41911.1 - 6.7e-07 29.0 1.0 0.033 14.0 0.4 3.4 2 1 0 2 2 2 2 LysM domain Tyrosinase PF00264.15 KEZ41912.1 - 2.6e-37 129.1 0.1 3.3e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.14 KEZ41912.1 - 0.04 14.1 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.5 KEZ41912.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain Ribonuc_L-PSP PF01042.16 KEZ41913.1 - 6.5e-27 93.6 0.0 8.6e-27 93.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulfotransfer_3 PF13469.1 KEZ41914.1 - 0.0014 19.5 0.0 0.0031 18.4 0.0 1.7 1 0 0 1 1 1 1 Sulfotransferase family BTB PF00651.26 KEZ41914.1 - 0.0027 17.6 0.1 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Methyltransf_23 PF13489.1 KEZ41916.1 - 2e-18 66.6 0.0 3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41916.1 - 1.5e-11 44.6 0.0 3.7e-11 43.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41916.1 - 1.2e-07 31.4 0.0 2.5e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41916.1 - 7.5e-07 29.7 0.0 6.8e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41916.1 - 9.7e-07 29.1 0.0 5.7e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ41916.1 - 5.1e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ41916.1 - 7.5e-05 21.9 0.0 0.00067 18.8 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ41916.1 - 0.0008 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KEZ41916.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 KEZ41916.1 - 0.022 13.8 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KEZ41916.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 3HCDH_N PF02737.13 KEZ41917.1 - 3.2e-27 95.3 0.0 8.9e-27 93.8 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEZ41917.1 - 6.4e-12 45.7 0.0 4.2e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Fig1 PF12351.3 KEZ41918.1 - 1e-06 28.7 0.1 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KEZ41918.1 - 0.0081 15.7 2.1 0.016 14.7 1.4 1.5 1 1 0 1 1 1 1 SUR7/PalI family DUF1358 PF07096.6 KEZ41918.1 - 0.026 14.2 0.1 0.055 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1358) DUF2175 PF09943.4 KEZ41919.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3176 PF11374.3 KEZ41920.1 - 7.4e-40 135.2 0.2 1.4e-39 134.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Corona_S2 PF01601.11 KEZ41920.1 - 0.12 10.4 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein AAA_22 PF13401.1 KEZ41922.1 - 0.00078 19.5 0.0 0.0044 17.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain Ank PF00023.25 KEZ41922.1 - 0.00083 19.0 0.0 0.0083 15.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat NACHT PF05729.7 KEZ41922.1 - 0.0033 17.1 2.1 0.016 14.8 0.0 3.0 3 1 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 KEZ41922.1 - 0.0056 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ41922.1 - 0.015 16.1 0.0 0.05 14.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEZ41922.1 - 0.021 15.1 0.0 0.09 13.0 0.0 2.1 1 0 0 1 1 1 0 ABC transporter DUF1319 PF07028.6 KEZ41922.1 - 0.022 14.9 3.5 0.64 10.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) RNA_helicase PF00910.17 KEZ41922.1 - 0.032 14.3 0.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 KEZ41922.1 - 0.046 12.5 0.1 0.53 9.0 0.0 2.3 1 1 0 2 2 2 0 NB-ARC domain Glyco_hydro_18 PF00704.23 KEZ41923.1 - 7.4e-51 173.6 0.2 1.1e-40 140.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 LysM PF01476.15 KEZ41924.1 - 1.4e-10 40.9 0.1 0.0037 17.1 0.0 4.7 5 0 0 5 5 5 3 LysM domain Ank_2 PF12796.2 KEZ41925.1 - 1.6e-05 25.1 0.0 3.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41925.1 - 1.9e-05 24.2 0.0 6.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 KEZ41925.1 - 2e-05 24.9 0.2 6.9e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ41925.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat LysM PF01476.15 KEZ41927.1 - 2.3e-32 110.6 0.0 4.6e-06 26.4 0.0 5.6 5 0 0 5 5 5 5 LysM domain HTH_Tnp_1 PF01527.15 KEZ41927.1 - 0.00097 19.0 0.0 10 6.1 0.0 4.1 4 0 0 4 4 4 1 Transposase Herpes_TK_C PF08465.5 KEZ41927.1 - 0.9 9.0 6.5 9.9 5.7 0.0 3.7 4 0 0 4 4 4 0 Thymidine kinase from Herpesvirus C-terminal Peptidase_C14 PF00656.17 KEZ41928.1 - 1.2e-05 25.1 0.0 3.5e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Caspase domain ubiquitin PF00240.18 KEZ41928.1 - 0.0066 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UN_NPL4 PF11543.3 KEZ41928.1 - 0.15 12.3 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 CorA PF01544.13 KEZ41929.1 - 1.1e-08 34.5 0.0 2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HATPase_c_3 PF13589.1 KEZ41931.1 - 1.1e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEZ41931.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.20 KEZ41932.1 - 2.1e-18 66.7 0.0 7.4e-18 65.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ41932.1 - 5.4e-09 36.1 0.0 8.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ41932.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KEZ41932.1 - 0.00087 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KEZ41932.1 - 0.004 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEZ41932.1 - 0.043 13.8 0.1 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 KEZ41933.1 - 2.6e-42 144.6 0.0 3.1e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ41933.1 - 1.3e-11 44.8 0.1 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KEZ41933.1 - 2.8e-05 24.3 0.2 8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEZ41933.1 - 7.8e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 KEZ41933.1 - 0.0013 18.2 0.1 0.0026 17.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KEZ41933.1 - 0.0024 16.9 0.2 0.0038 16.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KEZ41933.1 - 0.012 14.3 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KEZ41933.1 - 0.012 15.4 0.3 0.025 14.4 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KEZ41933.1 - 0.03 14.2 0.2 0.055 13.3 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.11 KEZ41933.1 - 0.14 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Chitin_synth_1 PF01644.12 KEZ41934.1 - 5.1e-69 231.2 0.0 1e-68 230.2 0.0 1.5 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_2 PF03142.10 KEZ41934.1 - 2.2e-30 105.5 0.0 2e-25 89.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KEZ41934.1 - 6.1e-19 67.4 0.2 1.3e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KEZ41934.1 - 2.3e-11 43.7 7.2 2.1e-10 40.6 5.0 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ41934.1 - 1.1e-09 38.4 0.0 2.4e-09 37.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 MARVEL PF01284.18 KEZ41935.1 - 0.0002 21.2 19.5 0.00078 19.2 13.5 1.8 1 1 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 KEZ41935.1 - 0.046 13.3 14.3 0.06 13.0 9.9 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF2417 PF10329.4 KEZ41935.1 - 0.24 10.7 8.3 0.29 10.4 5.8 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Tetraspannin PF00335.15 KEZ41935.1 - 0.26 10.5 10.6 0.48 9.6 7.3 1.4 1 1 0 1 1 1 0 Tetraspanin family 5TM-5TMR_LYT PF07694.7 KEZ41935.1 - 0.43 9.9 7.2 0.33 10.2 3.8 1.5 1 1 1 2 2 2 0 5TMR of 5TMR-LYT LrgB PF04172.11 KEZ41935.1 - 0.53 9.4 6.8 0.56 9.3 4.3 1.4 1 1 0 1 1 1 0 LrgB-like family CTP_transf_1 PF01148.15 KEZ41935.1 - 0.56 9.8 9.4 0.72 9.4 6.5 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family PrgI PF12666.2 KEZ41935.1 - 0.8 9.8 10.7 2.7 8.2 0.8 2.1 1 1 1 2 2 2 0 PrgI family protein DUF3938 PF13074.1 KEZ41935.1 - 1.5 8.7 6.2 0.41 10.5 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) DUF4293 PF14126.1 KEZ41935.1 - 3.7 7.4 10.9 11 5.9 7.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2306 PF10067.4 KEZ41935.1 - 7.9 6.6 12.1 4.6 7.4 2.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) FA_desaturase PF00487.19 KEZ41936.1 - 3.8e-34 118.2 23.4 5.9e-34 117.6 16.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3821 PF12863.2 KEZ41936.1 - 0.024 14.3 0.1 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) GST_N_2 PF13409.1 KEZ41937.1 - 9.7e-24 83.1 0.0 1.9e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ41937.1 - 4.7e-14 52.0 0.1 2e-13 50.0 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEZ41937.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KEZ41937.1 - 2.4e-06 27.6 0.0 5.9e-05 23.2 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEZ41937.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CFEM PF05730.6 KEZ41938.1 - 0.0022 17.7 7.3 0.0022 17.7 5.0 2.1 2 1 0 2 2 2 1 CFEM domain PetM PF08041.6 KEZ41938.1 - 0.22 11.0 0.1 0.22 11.0 0.1 2.7 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 p450 PF00067.17 KEZ41939.1 - 3.3e-45 154.4 0.0 4.3e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KEZ41940.1 - 7.5e-22 77.7 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ41940.1 - 3.7e-11 43.5 0.0 3.7e-10 40.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41940.1 - 3e-10 39.8 0.0 1.6e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ41940.1 - 6e-09 36.2 0.0 1.6e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41940.1 - 2.4e-07 31.1 0.0 9.2e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ41940.1 - 4.2e-07 30.2 0.0 1.2e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ41940.1 - 2.7e-05 24.1 0.0 0.00011 22.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain D123 PF07065.9 KEZ41940.1 - 8.3e-05 21.7 0.0 0.00017 20.8 0.0 1.4 1 1 0 1 1 1 1 D123 MTS PF05175.9 KEZ41940.1 - 0.00023 20.5 0.0 0.00067 19.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 KEZ41940.1 - 0.0013 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KEZ41940.1 - 0.033 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KEZ41940.1 - 0.037 13.0 0.0 0.081 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KEZ41940.1 - 0.14 11.2 0.0 0.66 8.9 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GMC_oxred_N PF00732.14 KEZ41941.1 - 1.3e-57 195.1 0.0 1.8e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ41941.1 - 4.1e-31 108.2 0.0 8.3e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ41941.1 - 3.2e-05 22.9 0.0 0.00015 20.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ41941.1 - 0.00019 21.4 0.0 0.00051 20.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ41941.1 - 0.00097 18.2 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KEZ41941.1 - 0.0021 16.9 0.1 0.23 10.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEZ41941.1 - 0.0071 15.3 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DUF2284 PF10050.4 KEZ41942.1 - 0.0052 16.3 35.6 0.63 9.6 0.7 4.9 5 0 0 5 5 5 4 Predicted metal-binding protein (DUF2284) Pkinase_Tyr PF07714.12 KEZ41943.1 - 0.00042 19.4 0.0 0.0015 17.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PAX PF00292.13 KEZ41943.1 - 0.0018 17.9 0.1 0.032 13.9 0.0 2.7 3 0 0 3 3 3 1 'Paired box' domain Pkinase PF00069.20 KEZ41943.1 - 0.0038 16.4 0.0 0.016 14.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KEZ41944.1 - 1.5e-43 148.8 0.0 1.9e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ41944.1 - 1.2e-18 67.1 0.0 1.7e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.1 KEZ41944.1 - 9.8e-06 25.0 0.3 6.2e-05 22.5 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.23 KEZ41944.1 - 0.00061 19.1 1.2 0.0086 15.4 0.1 3.2 3 0 0 3 3 3 1 SH3 domain Kinase-like PF14531.1 KEZ41944.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KEZ41944.1 - 0.03 13.3 0.0 0.083 11.9 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3433 PF11915.3 KEZ41946.1 - 2e-17 63.1 7.6 2.2e-14 53.3 1.2 4.2 4 1 1 5 5 5 2 Protein of unknown function (DUF3433) Shikimate_dh_N PF08501.6 KEZ41947.1 - 9.7e-21 73.6 0.0 1.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KEZ41947.1 - 2.5e-15 56.7 0.0 3.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 KEZ41947.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sugar_tr PF00083.19 KEZ41948.1 - 1.4e-132 442.5 25.4 1.6e-132 442.3 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ41948.1 - 2.6e-25 88.8 26.2 2.6e-25 88.8 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ41949.1 - 8e-16 57.6 0.0 1.1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ41950.1 - 6e-39 133.7 36.9 8.1e-39 133.3 25.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 KEZ41950.1 - 0.0017 16.5 3.1 0.0026 15.9 2.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector FAD_binding_3 PF01494.14 KEZ41950.1 - 0.0058 15.7 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DHquinase_I PF01487.10 KEZ41951.1 - 1.2e-40 139.6 0.0 2.8e-40 138.3 0.0 1.6 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KEZ41951.1 - 2.8e-21 75.3 0.0 6.5e-21 74.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 KEZ41951.1 - 9.4e-16 58.0 0.0 2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 KEZ41951.1 - 5.9e-13 49.0 0.2 2.1e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KEZ41951.1 - 0.0036 17.6 0.1 0.0097 16.3 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 KEZ41951.1 - 0.014 15.2 0.1 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family AAA_17 PF13207.1 KEZ41951.1 - 0.043 14.6 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain OCD_Mu_crystall PF02423.10 KEZ41951.1 - 0.059 12.1 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family cobW PF02492.14 KEZ41952.1 - 6.4e-47 159.2 7.4 7.6e-36 123.2 0.3 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KEZ41952.1 - 5.8e-17 61.2 0.1 1.9e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 KEZ41952.1 - 7.6e-06 24.8 0.7 0.002 16.9 0.0 2.2 2 0 0 2 2 2 2 ArgK protein CbiA PF01656.18 KEZ41952.1 - 0.00014 21.3 0.5 0.00042 19.7 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KEZ41952.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KEZ41952.1 - 0.0047 16.9 0.9 0.018 15.0 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KEZ41952.1 - 0.0072 16.2 0.1 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEZ41952.1 - 0.016 14.6 0.4 0.05 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 KEZ41952.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KEZ41952.1 - 0.022 14.8 0.1 0.075 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEZ41952.1 - 0.027 14.3 0.0 0.093 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KEZ41952.1 - 0.033 13.6 1.1 3.6 6.9 0.2 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain UPF0079 PF02367.12 KEZ41952.1 - 0.033 13.8 0.0 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SHOCT PF09851.4 KEZ41952.1 - 0.034 13.6 2.9 6.7 6.3 0.1 3.8 3 0 0 3 3 3 0 Short C-terminal domain ATP_bind_1 PF03029.12 KEZ41952.1 - 0.066 12.7 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 KEZ41952.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KEZ41952.1 - 0.085 13.1 0.0 0.34 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEZ41952.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 KEZ41952.1 - 0.15 11.8 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TFR_dimer PF04253.10 KEZ41953.1 - 2.4e-15 56.1 0.0 3.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KEZ41953.1 - 1.4e-14 54.2 0.0 2.9e-14 53.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEZ41953.1 - 7.1e-06 25.6 0.3 2.8e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KEZ41953.1 - 0.0015 18.0 0.0 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Alpha-amylase PF00128.19 KEZ41954.1 - 1.9e-62 211.4 0.0 3.1e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 KEZ41954.1 - 4.2e-27 93.5 0.3 1e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 KEZ41954.1 - 6.5e-22 77.4 0.0 2e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) CBM_25 PF03423.8 KEZ41954.1 - 0.0086 16.1 0.2 0.094 12.8 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain (family 25) p450 PF00067.17 KEZ41955.1 - 1.1e-57 195.6 0.0 1.3e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KEZ41956.1 - 7.5e-26 91.0 0.5 1e-25 90.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ41956.1 - 4.5e-23 82.2 0.1 6e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ41956.1 - 1.3e-09 37.9 0.1 1.8e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 KEZ41956.1 - 0.012 15.1 0.2 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 3HCDH_N PF02737.13 KEZ41956.1 - 0.031 13.9 0.5 0.05 13.2 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KEZ41956.1 - 0.036 13.1 2.1 0.094 11.7 0.3 2.2 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 KEZ41956.1 - 0.052 13.3 1.5 0.1 12.4 1.1 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain G-alpha PF00503.15 KEZ41957.1 - 1.4e-59 201.7 0.6 2.8e-54 184.2 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 KEZ41957.1 - 4.7e-12 45.4 0.1 9.7e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ41957.1 - 0.0013 17.8 0.9 0.0046 16.1 0.0 2.2 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region Fungal_trans PF04082.13 KEZ41960.1 - 2.7e-16 59.2 0.9 4.8e-16 58.4 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CodY PF06018.9 KEZ41960.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 CodY GAF-like domain MFS_1 PF07690.11 KEZ41961.1 - 1.3e-35 122.8 28.9 2e-35 122.1 19.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Pax2_C PF12403.3 KEZ41962.1 - 0.071 12.7 0.6 0.21 11.2 0.3 1.7 1 1 1 2 2 2 0 Paired-box protein 2 C terminal Pyr_redox_3 PF13738.1 KEZ41963.1 - 9.1e-21 74.8 0.0 3.5e-19 69.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ41963.1 - 2.4e-11 42.5 0.0 1e-10 40.5 0.0 2.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ41963.1 - 2.7e-10 39.6 0.0 6.9e-09 35.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEZ41963.1 - 5.2e-10 39.5 0.0 1.2e-07 31.8 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ41963.1 - 7.7e-06 25.7 0.3 0.1 12.3 0.0 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KEZ41963.1 - 2.9e-05 23.1 0.0 0.46 9.3 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ41963.1 - 3.1e-05 23.9 0.0 0.00011 22.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ41963.1 - 0.0013 17.7 0.0 0.11 11.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KEZ41963.1 - 0.033 13.2 0.1 0.17 10.9 0.0 2.2 3 0 0 3 3 3 0 Thi4 family Amino_oxidase PF01593.19 KEZ41963.1 - 0.041 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase B_lectin PF01453.19 KEZ41964.1 - 6.4e-13 48.5 0.6 6.9e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 D-mannose binding lectin Chitin_synth_1N PF08407.6 KEZ41965.1 - 8.4e-17 60.6 0.0 2e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal CRAL_TRIO PF00650.15 KEZ41965.1 - 0.11 11.9 0.0 0.98 8.8 0.0 2.1 2 0 0 2 2 2 0 CRAL/TRIO domain TRI12 PF06609.8 KEZ41966.1 - 1.9e-23 82.5 23.2 2.8e-23 81.9 16.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KEZ41966.1 - 4.7e-22 78.1 38.2 4.7e-22 78.1 26.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 KEZ41967.1 - 1.9e-70 237.7 0.0 2.6e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cu-oxidase_2 PF07731.9 KEZ41968.1 - 5.2e-39 132.9 4.7 8.6e-38 128.9 0.1 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEZ41968.1 - 1.4e-37 128.0 2.1 1.4e-37 128.0 1.5 2.3 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KEZ41968.1 - 2.7e-34 118.3 0.2 7.4e-33 113.7 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase FliC PF12445.3 KEZ41969.1 - 0.0097 16.0 1.0 0.017 15.2 0.7 1.4 1 1 0 1 1 1 1 Flagellin protein AMP-binding PF00501.23 KEZ41970.1 - 1.2e-79 267.6 0.0 1.6e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ41970.1 - 5e-10 40.1 0.1 2e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3104 PF11302.3 KEZ41970.1 - 0.1 11.9 0.2 0.57 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) Fungal_trans PF04082.13 KEZ41971.1 - 1.4e-17 63.3 0.7 2.2e-17 62.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.19 KEZ41972.1 - 4e-32 111.3 0.8 5.6e-32 110.9 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ41972.1 - 9.5e-21 73.0 0.2 1.8e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEZ41972.1 - 2.2e-18 66.8 0.1 8.2e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KEZ41972.1 - 0.0029 17.8 0.1 0.006 16.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KEZ41972.1 - 0.39 10.0 3.7 1.1 8.5 1.5 2.2 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short PF00106.20 KEZ41973.1 - 5.8e-30 104.4 0.6 8.3e-30 103.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ41973.1 - 4.1e-16 59.1 0.7 8.2e-16 58.1 0.5 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ41973.1 - 2.1e-14 53.8 0.2 4.2e-14 52.9 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEZ41973.1 - 0.0055 16.1 0.2 0.0074 15.7 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEZ41973.1 - 0.025 14.3 0.2 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.13 KEZ41973.1 - 0.068 13.1 0.2 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Hydrolase PF00702.21 KEZ41973.1 - 0.068 13.5 0.1 0.44 10.9 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase 2-Hacid_dh_C PF02826.14 KEZ41973.1 - 0.086 11.9 0.4 0.15 11.1 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KEZ41973.1 - 0.12 11.9 1.3 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.11 KEZ41974.1 - 4e-34 117.8 25.7 6.5e-34 117.1 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 KEZ41974.1 - 0.052 12.6 0.8 0.082 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) MFS_1 PF07690.11 KEZ41975.1 - 2.7e-33 115.1 42.5 3.7e-24 85.1 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ41975.1 - 0.0056 16.4 3.7 3.6 7.4 0.3 4.2 3 1 1 4 4 4 2 MFS_1 like family EF-hand_7 PF13499.1 KEZ41975.1 - 0.04 14.0 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair MFS_1 PF07690.11 KEZ41976.1 - 3.8e-27 94.9 58.7 1.3e-21 76.7 19.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Yip1 PF04893.12 KEZ41977.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain Ank_2 PF12796.2 KEZ41978.1 - 1e-33 115.5 0.0 6.3e-17 61.6 0.1 4.9 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ41978.1 - 2.8e-22 77.3 8.9 9.5e-07 28.3 0.0 8.1 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 KEZ41978.1 - 2.6e-15 56.1 4.6 6.3e-07 29.4 0.0 5.9 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ41978.1 - 2e-13 49.1 3.0 0.005 16.9 0.0 7.3 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 KEZ41978.1 - 3.2e-12 46.6 5.7 0.0006 20.2 0.0 6.6 6 2 1 7 7 6 2 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ41978.1 - 6.8e-07 29.0 0.0 2.4e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ41978.1 - 6.1e-05 23.0 2.5 0.00041 20.3 0.0 3.6 5 0 0 5 5 5 1 AAA ATPase domain MMR_HSR1 PF01926.18 KEZ41978.1 - 0.014 15.3 0.1 0.15 12.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3683 PF12447.3 KEZ41978.1 - 0.078 12.8 0.0 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) Tex_N PF09371.5 KEZ41978.1 - 0.2 10.9 0.0 0.2 10.9 0.0 3.3 5 0 0 5 5 5 0 Tex-like protein N-terminal domain RNA_helicase PF00910.17 KEZ41978.1 - 0.23 11.6 0.0 1.9 8.7 0.0 2.5 3 0 0 3 3 3 0 RNA helicase Y_phosphatase3 PF13350.1 KEZ41979.1 - 9.7e-35 120.2 0.0 1.4e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KEZ41979.1 - 2.3e-06 27.5 0.0 9.9e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KEZ41979.1 - 0.00094 18.5 0.0 0.0013 18.1 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEZ41979.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 KEZ41979.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Sterol_MT_C PF08498.5 KEZ41980.1 - 1e-23 83.0 0.1 1.9e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KEZ41980.1 - 4.8e-23 81.4 0.0 1.1e-22 80.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ41980.1 - 5e-21 74.8 0.0 7.7e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ41980.1 - 2.3e-17 63.1 0.0 4.5e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ41980.1 - 9.1e-17 61.2 0.0 1.8e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ41980.1 - 9.6e-16 57.5 0.0 1.9e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KEZ41980.1 - 2.3e-15 56.4 0.6 4.4e-15 55.4 0.1 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KEZ41980.1 - 4.8e-14 52.8 0.0 1e-13 51.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ41980.1 - 2.7e-12 46.7 0.0 8.1e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ41980.1 - 4.1e-12 46.4 0.0 7.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ41980.1 - 1.9e-06 27.3 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 KEZ41980.1 - 2.4e-06 27.2 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 KEZ41980.1 - 5.3e-06 26.1 0.0 9.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KEZ41980.1 - 0.00021 20.5 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 KEZ41980.1 - 0.00021 20.4 0.0 0.00036 19.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 KEZ41980.1 - 0.0021 17.3 0.4 0.0037 16.4 0.2 1.7 1 1 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 KEZ41980.1 - 0.0023 17.5 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 KEZ41980.1 - 0.0031 17.1 0.0 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 KEZ41980.1 - 0.0039 16.8 0.2 0.008 15.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEZ41980.1 - 0.0088 15.1 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.7 KEZ41980.1 - 0.0089 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 KEZ41980.1 - 0.014 15.4 0.0 0.038 13.9 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Pox_MCEL PF03291.11 KEZ41980.1 - 0.03 13.2 0.0 0.064 12.1 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_24 PF13578.1 KEZ41980.1 - 0.043 14.6 0.0 0.12 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KEZ41981.1 - 2.3e-10 41.4 0.0 4.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEZ41981.1 - 5.8e-09 35.5 0.0 9.9e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ41981.1 - 7.2e-08 32.1 0.9 3.7e-06 26.6 0.5 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KEZ41981.1 - 0.0049 16.8 0.0 0.007 16.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding IBR PF01485.16 KEZ41982.1 - 5.2e-13 48.6 23.2 5.7e-13 48.5 0.5 5.7 6 1 1 7 7 7 2 IBR domain Ribosomal_S27e PF01667.12 KEZ41982.1 - 0.4 10.2 3.6 15 5.1 0.1 2.9 2 0 0 2 2 2 0 Ribosomal protein S27 Herpes_US9 PF06072.6 KEZ41983.1 - 0.16 11.8 1.5 0.24 11.2 1.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Cupin_2 PF07883.6 KEZ41984.1 - 0.0044 16.4 1.5 0.046 13.2 0.3 2.5 2 1 0 2 2 2 1 Cupin domain Hpre_diP_synt_I PF07456.6 KEZ41985.1 - 0.041 13.7 0.4 0.041 13.7 0.3 2.0 2 1 1 3 3 3 0 Heptaprenyl diphosphate synthase component I RTA1 PF04479.8 KEZ41986.1 - 8.6e-35 120.2 8.4 1.3e-34 119.6 5.8 1.2 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.11 KEZ41987.1 - 2.2e-26 92.3 26.1 2.2e-26 92.3 18.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ41987.1 - 9.1e-06 24.5 8.2 9.1e-06 24.5 5.7 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter Fungal_trans_2 PF11951.3 KEZ41988.1 - 5.3e-05 21.9 0.3 0.00052 18.7 0.1 2.0 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ41988.1 - 0.023 14.6 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KEZ41990.1 - 0.00018 21.3 11.0 0.00033 20.5 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-SNAP50_C PF12251.3 KEZ41990.1 - 0.26 10.6 2.4 0.5 9.7 1.6 1.4 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Glyoxalase PF00903.20 KEZ41991.1 - 4.2e-21 75.2 0.4 2.1e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KEZ41991.1 - 2.2e-11 43.7 0.1 0.0001 22.2 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEZ41991.1 - 5.5e-10 39.8 0.0 0.00037 21.0 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KEZ41991.1 - 8.5e-07 28.9 0.1 7.8e-05 22.6 0.0 2.6 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KEZ41991.1 - 0.019 14.9 0.1 1.3 8.9 0.0 3.3 3 1 0 3 3 3 0 Glyoxalase-like domain HgmA PF04209.8 KEZ41992.1 - 1.5e-176 586.9 0.0 2e-176 586.5 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PEP_mutase PF13714.1 KEZ41993.1 - 6.5e-55 185.9 0.1 8.4e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KEZ41993.1 - 1.8e-14 52.8 0.3 2.7e-14 52.3 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 KEZ41993.1 - 0.00011 21.4 0.1 0.087 11.9 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase MFS_1 PF07690.11 KEZ41994.1 - 4e-28 98.1 12.1 5e-28 97.8 8.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 KEZ41995.1 - 6e-13 48.3 5.9 1.1e-12 47.5 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEZ41995.1 - 6.5e-09 35.3 2.5 1.1e-08 34.6 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEZ41995.1 - 4.7e-08 32.5 4.3 7.4e-08 31.9 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEZ41995.1 - 8.9e-07 28.9 0.4 1.8e-06 27.9 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEZ41995.1 - 9.7e-07 28.3 2.0 1.7e-06 27.6 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ41995.1 - 1.1e-06 28.6 4.8 1.9e-06 27.7 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEZ41995.1 - 0.0076 16.0 2.2 0.018 14.8 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KEZ41995.1 - 0.052 13.2 3.6 0.12 12.1 2.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 KEZ41995.1 - 0.1 12.3 2.8 0.19 11.4 1.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KEZ41995.1 - 0.22 11.1 4.8 0.41 10.2 3.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GAGA PF09237.6 KEZ41995.1 - 0.36 10.4 2.0 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 GAGA factor Prok-RING_4 PF14447.1 KEZ41995.1 - 1.3 8.6 5.3 3.2 7.3 3.7 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 p450 PF00067.17 KEZ41996.1 - 9.4e-60 202.4 0.0 4.3e-57 193.6 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Amidohydro_2 PF04909.9 KEZ41997.1 - 3.8e-41 141.4 0.2 4.5e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase FMN_dh PF01070.13 KEZ41998.1 - 6.5e-119 396.9 0.0 9.5e-119 396.3 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase AMP-binding PF00501.23 KEZ41998.1 - 3e-67 226.8 0.0 4.3e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ECH PF00378.15 KEZ41998.1 - 1.9e-20 73.0 0.6 3.5e-10 39.4 0.1 3.0 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase family Glu_synthase PF01645.12 KEZ41998.1 - 3e-05 23.1 0.1 5.2e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KEZ41998.1 - 0.00024 20.3 1.4 0.00045 19.4 1.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KEZ41998.1 - 0.002 17.2 0.1 0.14 11.2 0.1 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KEZ41998.1 - 0.0024 16.8 0.8 0.0045 15.9 0.6 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KEZ41998.1 - 0.093 11.9 0.1 0.56 9.4 0.0 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein MFS_1 PF07690.11 KEZ41999.1 - 1.8e-19 69.6 34.0 3.7e-18 65.3 23.6 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 KEZ41999.1 - 0.00091 17.4 4.0 0.066 11.2 0.3 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Pox_A14 PF05767.7 KEZ41999.1 - 0.024 14.5 4.3 1.4 8.8 0.5 3.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.17 KEZ42000.1 - 1.2e-60 205.4 0.0 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RPE65 PF03055.10 KEZ42001.1 - 2.5e-113 379.2 0.0 3.3e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FAD_binding_4 PF01565.18 KEZ42001.1 - 7.9e-26 90.1 0.1 1.7e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KEZ42001.1 - 1.9e-07 30.6 0.0 3.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Ribonuc_L-PSP PF01042.16 KEZ42002.1 - 1.3e-34 118.6 0.0 1.4e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_23 PF13489.1 KEZ42004.1 - 2.5e-14 53.3 0.0 3.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42004.1 - 3.7e-10 39.5 0.0 1.6e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42004.1 - 7.2e-10 39.2 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42004.1 - 1e-06 29.1 0.0 2.9e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ42004.1 - 0.00038 20.7 0.0 0.0015 18.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42004.1 - 0.0022 18.5 0.1 0.027 15.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KEZ42004.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 KEZ42004.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_N PF08240.7 KEZ42006.1 - 5.8e-27 93.6 2.7 9.4e-27 92.9 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 KEZ42006.1 - 1.9e-13 50.4 0.0 7.8e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEZ42006.1 - 3.2e-13 49.0 0.0 4.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.21 KEZ42006.1 - 1.1e-12 47.6 0.0 3.3e-12 46.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KEZ42006.1 - 2.2e-11 44.1 0.0 9e-11 42.1 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEZ42006.1 - 2.1e-09 36.6 0.1 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KEZ42006.1 - 9e-05 21.8 0.0 0.00021 20.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KEZ42006.1 - 0.00012 22.0 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ42006.1 - 0.0013 17.9 0.1 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KEZ42006.1 - 0.0036 16.2 0.0 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KEZ42006.1 - 0.013 15.1 0.1 0.04 13.5 0.1 1.8 1 1 0 1 1 1 0 KR domain NAD_binding_2 PF03446.10 KEZ42006.1 - 0.023 14.5 0.1 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.19 KEZ42007.1 - 2.3e-101 339.6 14.1 2.7e-101 339.3 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42007.1 - 5.3e-23 81.3 23.7 2.3e-18 66.0 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KEZ42008.1 - 9.1e-10 38.2 9.6 1.9e-09 37.2 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ42008.1 - 0.0038 16.1 0.4 1.8 7.3 0.0 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain MR_MLE_C PF13378.1 KEZ42009.1 - 3.4e-15 55.9 0.0 7.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KEZ42009.1 - 2.2e-12 47.3 0.0 6.2e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KEZ42009.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KEZ42009.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DUF308 PF03729.8 KEZ42010.1 - 1.2 9.2 9.1 4.3 7.3 0.1 2.6 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Peptidase_M24 PF00557.19 KEZ42011.1 - 1.4e-39 135.8 0.0 1.8e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_23 PF13489.1 KEZ42012.1 - 6.9e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42012.1 - 2.8e-06 27.7 0.0 6.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42012.1 - 0.0019 18.6 0.0 0.01 16.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42012.1 - 0.11 12.1 0.0 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 KEZ42013.1 - 1e-05 25.4 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ42013.1 - 0.00089 18.9 0.0 0.0022 17.6 0.0 1.6 2 0 0 2 2 2 1 KR domain HET PF06985.6 KEZ42014.1 - 4.4e-22 78.7 0.0 7.5e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4096 PF13340.1 KEZ42014.1 - 0.053 13.3 0.1 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) zf-C2H2 PF00096.21 KEZ42015.1 - 1.1e-05 25.4 14.8 0.038 14.3 1.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KEZ42015.1 - 1.3e-05 25.2 5.2 0.0065 16.5 0.5 2.8 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KEZ42015.1 - 0.00014 21.9 10.3 0.21 11.9 0.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ42015.1 - 0.00021 21.4 6.3 1.2 9.5 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn-ribbon_8 PF09723.5 KEZ42015.1 - 0.00028 20.7 4.3 0.26 11.2 0.1 3.5 3 1 0 3 3 3 1 Zinc ribbon domain zf-C2H2_jaz PF12171.3 KEZ42015.1 - 0.00049 20.1 9.3 0.036 14.2 0.4 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KEZ42015.1 - 0.00057 19.4 3.7 0.19 11.4 0.1 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.2 KEZ42015.1 - 0.0042 17.2 10.8 0.24 11.6 0.5 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.9 KEZ42015.1 - 0.011 15.1 0.9 4 6.9 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.7 KEZ42015.1 - 0.027 14.5 10.2 0.35 11.0 0.3 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 KEZ42015.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.2 3 1 0 3 3 3 0 zinc-finger zf-DBF PF07535.7 KEZ42015.1 - 0.42 10.3 3.8 0.48 10.1 0.3 2.6 3 0 0 3 3 3 0 DBF zinc finger AKAP95 PF04988.7 KEZ42015.1 - 0.93 9.2 3.3 1.1 8.9 0.7 2.1 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 KEZ42015.1 - 1.1 9.3 9.6 2.5 8.1 1.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger HET PF06985.6 KEZ42016.1 - 9e-31 106.8 0.0 1.3e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC2_membrane PF01061.19 KEZ42017.1 - 1e-93 312.3 55.9 1.4e-48 164.8 11.1 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KEZ42017.1 - 1.2e-36 124.5 0.5 2.8e-33 113.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KEZ42017.1 - 2.1e-34 118.7 0.0 8.7e-16 58.4 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KEZ42017.1 - 3.6e-18 65.4 0.1 9.9e-18 64.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEZ42017.1 - 1.8e-08 33.9 0.1 5e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ42017.1 - 1.8e-07 31.3 2.4 2.4e-06 27.6 0.1 2.7 3 0 0 3 3 2 1 AAA ATPase domain cobW PF02492.14 KEZ42017.1 - 8.4e-05 22.0 1.0 0.0041 16.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KEZ42017.1 - 9.2e-05 22.3 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KEZ42017.1 - 0.00056 19.1 0.1 0.009 15.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KEZ42017.1 - 0.00092 18.9 0.2 1.3 8.8 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KEZ42017.1 - 0.0018 18.4 0.1 0.34 11.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ42017.1 - 0.0018 18.3 0.1 0.79 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ42017.1 - 0.0021 18.8 0.1 0.68 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEZ42017.1 - 0.0029 17.2 0.2 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ42017.1 - 0.0038 16.7 0.5 0.025 14.1 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KEZ42017.1 - 0.0059 16.2 0.2 0.99 9.0 0.1 2.5 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KEZ42017.1 - 0.0082 15.7 1.1 2.8 7.5 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 KEZ42017.1 - 0.019 14.9 0.0 0.8 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEZ42017.1 - 0.031 14.5 0.1 0.46 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KEZ42017.1 - 0.045 12.9 0.0 5.7 6.0 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEZ42017.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEZ42017.1 - 0.2 11.1 1.0 4 6.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEZ42017.1 - 0.24 11.9 0.0 14 6.2 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein ABC2_membrane_3 PF12698.2 KEZ42017.1 - 0.35 9.8 42.1 0.37 9.7 10.2 3.1 2 2 0 2 2 2 0 ABC-2 family transporter protein AAA_28 PF13521.1 KEZ42017.1 - 0.62 10.0 3.6 2 8.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain Peptidase_M20 PF01546.23 KEZ42019.1 - 2.4e-22 79.3 0.1 3.4e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEZ42019.1 - 1.2e-17 63.6 0.0 1.9e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEZ42019.1 - 0.00071 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 YchF-GTPase_C PF06071.8 KEZ42020.1 - 1e-37 127.7 0.2 2.5e-37 126.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KEZ42020.1 - 2.8e-06 27.2 0.0 4.8e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase p450 PF00067.17 KEZ42021.1 - 0.043 12.3 0.0 0.055 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 adh_short PF00106.20 KEZ42022.1 - 1.2e-28 100.1 0.1 2.4e-28 99.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ42022.1 - 6.3e-24 85.0 0.0 7.4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ42022.1 - 2.1e-08 34.0 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEZ42022.1 - 0.00059 18.8 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KEZ42022.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 KEZ42023.1 - 7.5e-27 94.2 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KEZ42023.1 - 1.2e-15 57.0 0.0 1.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KEZ42023.1 - 8.3e-07 28.8 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aconitase PF00330.15 KEZ42023.1 - 2.4e-05 23.0 0.0 3.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF2974 PF11187.3 KEZ42023.1 - 0.033 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KEZ42023.1 - 0.036 13.2 0.0 0.36 10.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.20 KEZ42024.1 - 3.4e-17 62.8 0.0 7.6e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ42024.1 - 2.1e-11 44.0 0.0 2.9e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ42024.1 - 1.2e-06 28.3 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 KEZ42025.1 - 6.6e-25 87.9 0.0 9.5e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ42025.1 - 2.8e-16 60.0 0.0 3.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ42025.1 - 6.4e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ42025.1 - 0.00024 20.6 0.1 0.00064 19.2 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEZ42025.1 - 0.0029 17.3 0.4 0.03 14.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_8 PF13450.1 KEZ42025.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 KEZ42026.1 - 1.6e-25 89.5 18.9 1.6e-25 89.5 13.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ42026.1 - 5.7e-10 38.3 13.2 5.7e-10 38.3 9.1 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter CBM_20 PF00686.14 KEZ42028.1 - 5e-34 115.7 1.1 9e-34 114.9 0.7 1.4 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 KEZ42028.1 - 8.1e-10 39.2 0.1 2e-07 31.4 0.0 2.5 1 1 0 1 1 1 1 Chitin binding domain DUF2854 PF11016.3 KEZ42028.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Fungal_lectin PF07938.7 KEZ42029.1 - 2.3e-07 30.4 3.0 0.0047 16.2 1.2 2.1 2 0 0 2 2 2 2 Fungal fucose-specific lectin Glyco_hydro_18 PF00704.23 KEZ42030.1 - 7.6e-102 341.2 7.2 8.8e-102 341.0 5.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HET PF06985.6 KEZ42031.1 - 5.8e-34 117.2 0.6 1.4e-33 115.9 0.4 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Epimerase PF01370.16 KEZ42032.1 - 6.9e-09 35.4 0.0 0.00055 19.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEZ42032.1 - 2.2e-05 24.7 0.0 5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KEZ42032.1 - 5.2e-05 22.6 0.0 8.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KEZ42032.1 - 0.0012 17.8 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KEZ42032.1 - 0.028 14.4 0.0 0.19 11.7 0.0 2.5 2 1 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ42032.1 - 0.13 10.9 0.0 0.34 9.5 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 KEZ42034.1 - 1.6e-48 165.4 0.0 2.1e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KEZ42035.1 - 4.6e-24 84.9 0.0 6.4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42035.1 - 4.8e-11 42.4 0.0 3.8e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42035.1 - 7.1e-11 42.6 0.0 1.1e-09 38.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42035.1 - 8.4e-10 39.0 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42035.1 - 7.6e-09 35.9 0.0 3.9e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ42035.1 - 1.6e-06 28.4 0.0 5.5e-06 26.6 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ42035.1 - 0.00024 21.1 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ42035.1 - 0.00052 20.0 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ42035.1 - 0.0015 17.6 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ42035.1 - 0.0036 16.7 0.0 0.017 14.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEZ42035.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KEZ42035.1 - 0.044 12.8 0.0 0.32 10.0 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Inhibitor_I36 PF03995.8 KEZ42036.1 - 0.051 13.9 1.4 0.077 13.3 0.9 1.3 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Ldl_recept_b PF00058.12 KEZ42036.1 - 0.062 13.6 6.9 1 9.7 0.1 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B Fungal_trans_2 PF11951.3 KEZ42037.1 - 0.0011 17.6 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_18 PF00704.23 KEZ42038.1 - 4.1e-42 144.8 6.1 7e-42 144.0 4.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KEZ42038.1 - 1.5e-10 40.7 0.3 0.00052 19.8 0.1 2.7 2 0 0 2 2 2 2 LysM domain DNase_NucA_NucB PF14040.1 KEZ42038.1 - 1.4e-05 25.2 0.2 4.5e-05 23.5 0.2 1.9 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.14 KEZ42038.1 - 0.00019 21.3 2.2 0.00019 21.3 1.5 3.8 4 0 0 4 4 4 1 Chitin recognition protein DUF4450 PF14614.1 KEZ42038.1 - 0.12 11.5 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) DUF3659 PF12396.3 KEZ42039.1 - 4.4e-118 385.0 46.4 4.3e-23 80.7 1.8 6.4 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) GCV_T_C PF08669.6 KEZ42039.1 - 0.02 14.9 0.4 17 5.5 0.0 4.3 4 0 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain 2C_adapt PF08793.5 KEZ42039.1 - 0.063 13.1 0.0 0.5 10.2 0.0 2.6 3 0 0 3 3 3 0 2-cysteine adaptor domain zf-Tim10_DDP PF02953.10 KEZ42039.1 - 0.11 11.8 0.6 0.22 10.8 0.4 1.5 1 0 0 1 1 1 0 Tim10/DDP family zinc finger HNH_2 PF13391.1 KEZ42040.1 - 1.5e-10 40.6 0.0 3.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Carb_bind PF10645.4 KEZ42041.1 - 6.4e-13 48.2 4.3 6.4e-13 48.2 3.0 1.8 2 0 0 2 2 2 1 Carbohydrate binding ETRAMP PF09716.5 KEZ42043.1 - 0.037 13.9 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sugar_tr PF00083.19 KEZ42044.1 - 3.9e-89 299.3 26.0 9.2e-50 169.5 1.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42044.1 - 7.3e-09 34.7 35.5 2.8e-06 26.3 8.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phospholip_A2_3 PF09056.6 KEZ42045.1 - 7.4e-46 154.9 0.1 9.8e-46 154.5 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Clr5 PF14420.1 KEZ42046.1 - 9.7e-14 51.0 0.9 1.9e-13 50.0 0.6 1.5 1 0 0 1 1 1 1 Clr5 domain GFA PF04828.9 KEZ42047.1 - 2.3e-08 33.8 1.2 3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KEZ42047.1 - 0.0032 16.9 0.1 0.0032 16.9 0.1 2.2 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain SnoaL_2 PF12680.2 KEZ42048.1 - 9.4e-05 22.7 0.4 0.00013 22.3 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KEZ42048.1 - 0.0002 21.5 0.1 0.00024 21.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 KEZ42048.1 - 0.0058 16.5 0.5 0.0096 15.8 0.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KEZ42048.1 - 0.034 14.1 0.2 0.048 13.7 0.2 1.4 1 1 0 1 1 1 0 SnoaL-like domain Abhydrolase_6 PF12697.2 KEZ42049.1 - 2.3e-31 109.4 0.0 2.7e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ42049.1 - 7.6e-24 84.1 0.3 4.2e-23 81.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ42049.1 - 2.7e-17 63.0 0.0 2.1e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KEZ42049.1 - 4e-10 40.3 0.0 4.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KEZ42049.1 - 4.5e-07 29.6 0.0 9.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KEZ42049.1 - 5.1e-06 25.8 0.0 0.082 12.1 0.0 2.5 2 1 0 3 3 3 2 Prolyl oligopeptidase family PGAP1 PF07819.8 KEZ42049.1 - 9.9e-06 25.2 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 KEZ42049.1 - 1.3e-05 24.5 0.1 0.077 12.2 0.0 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.8 KEZ42049.1 - 0.00011 21.8 0.0 0.063 12.8 0.0 2.2 1 1 0 2 2 2 2 Serine hydrolase DUF676 PF05057.9 KEZ42049.1 - 0.00014 21.2 0.2 0.00022 20.5 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.11 KEZ42049.1 - 0.00022 20.7 0.2 0.075 12.4 0.0 3.0 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KEZ42049.1 - 0.00022 20.8 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KEZ42049.1 - 0.00052 19.5 0.0 0.0048 16.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KEZ42049.1 - 0.00084 18.9 0.5 0.002 17.7 0.2 1.5 1 1 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 KEZ42049.1 - 0.00098 18.6 0.1 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 KEZ42049.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme BAAT_C PF08840.6 KEZ42049.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 KEZ42049.1 - 0.0032 16.9 0.1 0.039 13.4 0.0 2.4 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Esterase_phd PF10503.4 KEZ42049.1 - 0.0088 15.3 0.3 0.021 14.0 0.1 1.6 1 1 1 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.7 KEZ42049.1 - 0.016 13.6 0.0 0.24 9.8 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.8 KEZ42049.1 - 0.024 12.9 1.6 1.4 7.1 0.2 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II HTH_29 PF13551.1 KEZ42049.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Chlorophyllase PF07224.6 KEZ42049.1 - 0.044 12.5 0.1 0.064 12.0 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF1057 PF06342.7 KEZ42049.1 - 0.074 11.8 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF900 PF05990.7 KEZ42049.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) MFS_1 PF07690.11 KEZ42050.1 - 6.7e-22 77.6 52.1 3.3e-11 42.4 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KEZ42050.1 - 0.14 12.2 10.3 0.073 13.1 1.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) MFS_2 PF13347.1 KEZ42050.1 - 0.16 10.3 35.0 0.0051 15.2 8.3 3.7 2 1 1 4 4 4 0 MFS/sugar transport protein DUF4066 PF13278.1 KEZ42051.1 - 1.5e-23 82.8 0.1 2.6e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEZ42051.1 - 1.3e-12 47.4 0.0 2.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.1 KEZ42051.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KEZ42051.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Transp_cyt_pur PF02133.10 KEZ42052.1 - 4.2e-61 206.8 26.1 4.8e-61 206.6 18.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2393 PF09624.5 KEZ42053.1 - 0.0078 15.7 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2393) p450 PF00067.17 KEZ42055.1 - 2.4e-71 240.6 0.0 3.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KEZ42055.1 - 1.8e-34 119.0 0.0 3.3e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEZ42055.1 - 1.7e-24 86.4 0.0 3.6e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEZ42055.1 - 5.7e-12 46.1 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KEZ42055.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.6 KEZ42055.1 - 0.044 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like NAD_binding_6 PF08030.7 KEZ42055.1 - 0.16 11.8 0.1 11 5.9 0.3 2.8 3 0 0 3 3 3 0 Ferric reductase NAD binding domain adh_short PF00106.20 KEZ42056.1 - 2.1e-21 76.5 0.0 2.7e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ42056.1 - 1.5e-07 31.4 0.0 2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ42056.1 - 1.5e-07 31.2 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KEZ42056.1 - 0.074 12.1 0.0 0.52 9.4 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DHquinase_II PF01220.14 KEZ42056.1 - 0.09 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Dehydroquinase class II NAD_binding_10 PF13460.1 KEZ42056.1 - 0.1 12.5 0.2 0.28 11.1 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Sod_Fe_C PF02777.13 KEZ42057.1 - 1e-34 118.5 0.2 1.7e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEZ42057.1 - 4.5e-34 116.5 2.6 6.1e-34 116.1 0.6 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GATase_5 PF13507.1 KEZ42059.1 - 5.8e-97 323.6 0.0 8.9e-97 323.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KEZ42059.1 - 3.7e-44 150.3 0.5 9.5e-22 77.6 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KEZ42059.1 - 1.3e-22 79.8 1.6 3.5e-22 78.4 0.0 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Zn_clus PF00172.13 KEZ42060.1 - 5.3e-13 48.6 28.4 1.2e-06 28.3 5.3 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ42060.1 - 3.6e-06 26.0 0.8 0.00013 20.9 0.1 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain NmrA PF05368.8 KEZ42061.1 - 6.6e-31 107.3 0.0 1.6e-30 106.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ42061.1 - 6.8e-12 45.7 0.0 9.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEZ42061.1 - 0.00027 20.0 0.0 0.00041 19.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KEZ42061.1 - 0.0019 18.1 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 KEZ42061.1 - 0.0062 16.9 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KEZ42061.1 - 0.0091 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2784 PF10861.3 KEZ42061.1 - 0.049 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Methyltransf_23 PF13489.1 KEZ42062.1 - 1.4e-19 70.3 0.1 2.8e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42062.1 - 1e-11 44.6 0.0 9.4e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42062.1 - 1.5e-08 35.2 0.0 1.4e-07 32.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42062.1 - 2.2e-06 28.0 0.0 6.2e-06 26.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42062.1 - 1.2e-05 25.7 0.0 6.1e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ42062.1 - 9.3e-05 22.7 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ42062.1 - 0.0035 16.4 0.0 0.0084 15.1 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ42062.1 - 0.0077 16.2 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ42062.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KEZ42062.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KEZ42062.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KEZ42062.1 - 0.098 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF4661 PF15576.1 KEZ42062.1 - 0.12 11.9 0.4 0.46 10.0 0.8 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) Glyco_hydro_12 PF01670.11 KEZ42063.1 - 2.3e-05 24.2 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 WD40 PF00400.27 KEZ42064.1 - 2.2e-10 39.9 9.9 0.13 12.1 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat NACHT PF05729.7 KEZ42064.1 - 2.6e-09 36.9 0.1 5.5e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 KEZ42064.1 - 0.00088 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KEZ42064.1 - 0.0017 17.6 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEZ42064.1 - 0.0052 16.7 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_63 PF03200.11 KEZ42066.1 - 1.6e-119 400.0 0.0 7e-56 189.5 0.0 4.0 1 1 3 4 4 4 4 Mannosyl oligosaccharide glucosidase Ank_2 PF12796.2 KEZ42066.1 - 3.8e-05 23.9 0.0 0.00037 20.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ42066.1 - 0.0027 18.1 0.1 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KEZ42066.1 - 0.003 17.2 0.1 0.47 10.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ammonium_transp PF00909.16 KEZ42066.1 - 0.065 11.6 0.0 0.11 10.8 0.0 1.3 1 0 0 1 1 1 0 Ammonium Transporter Family MFS_1 PF07690.11 KEZ42067.1 - 1.8e-05 23.6 9.8 0.00024 19.9 6.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ42068.1 - 1.3e-18 66.8 0.0 2.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ42068.1 - 2.2e-07 30.6 9.7 4.2e-07 29.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.15 KEZ42069.1 - 1.6e-34 120.0 0.0 2.8e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KEZ42069.1 - 1.7e-17 64.3 0.0 7e-17 62.3 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 KEZ42069.1 - 5.2e-16 58.2 0.4 9.9e-16 57.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_5 PF13594.1 KEZ42069.1 - 1.1e-12 47.5 0.1 7.8e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KEZ42069.1 - 2.5e-08 33.5 0.2 2e-05 23.9 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family Zn_clus PF00172.13 KEZ42069.1 - 9.9e-07 28.5 9.9 2.3e-06 27.3 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEZ42070.1 - 8.9e-31 106.8 32.1 1.1e-30 106.5 22.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 KEZ42070.1 - 0.013 15.8 0.4 0.04 14.3 0.2 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Iso_dh PF00180.15 KEZ42071.1 - 1.9e-85 286.8 0.0 2.3e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aldedh PF00171.17 KEZ42072.1 - 1.1e-147 492.1 0.0 1.3e-147 491.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEZ42072.1 - 0.019 14.1 0.1 3 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Aminotran_3 PF00202.16 KEZ42073.1 - 8e-99 330.6 0.0 9.4e-99 330.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III AF-4 PF05110.8 KEZ42073.1 - 0.055 11.3 0.0 0.072 10.9 0.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MFS_1 PF07690.11 KEZ42075.1 - 5.6e-31 107.5 31.4 3.9e-29 101.4 21.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 KEZ42075.1 - 0.0066 16.5 0.5 0.0066 16.5 0.3 4.2 2 2 2 4 4 4 1 NfeD-like C-terminal, partner-binding Neurensin PF14927.1 KEZ42075.1 - 0.14 11.4 0.7 3 7.2 0.2 2.5 2 0 0 2 2 2 0 Neurensin Glyoxalase PF00903.20 KEZ42076.1 - 4.7e-14 52.4 1.6 4.1e-11 42.9 0.5 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEZ42076.1 - 1.5e-09 38.4 1.6 0.0001 22.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KEZ42076.1 - 0.00055 19.9 0.2 0.0023 17.9 0.1 2.1 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ADH_zinc_N PF00107.21 KEZ42077.1 - 1.2e-21 76.5 0.8 8.8e-21 73.8 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ42077.1 - 1.3e-21 76.3 0.2 1.9e-21 75.8 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Gp_dh_N PF00044.19 KEZ42077.1 - 0.013 15.4 0.1 0.076 12.9 0.0 2.0 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 KEZ42077.1 - 0.028 13.1 0.4 0.042 12.6 0.3 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Aldedh PF00171.17 KEZ42078.1 - 6.1e-139 463.3 0.0 7.6e-139 462.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ42078.1 - 0.0032 16.2 0.0 0.016 13.9 0.0 2.0 2 1 0 2 2 2 1 Acyl-CoA reductase (LuxC) Peptidase_S15 PF02129.13 KEZ42079.1 - 2.1e-43 148.7 1.2 3.5e-43 147.9 0.9 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KEZ42079.1 - 6.6e-35 120.9 0.4 6.6e-35 120.9 0.3 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 KEZ42079.1 - 0.00015 21.5 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEZ42079.1 - 0.019 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase FAD_binding_3 PF01494.14 KEZ42080.1 - 3.7e-89 299.2 0.0 5e-89 298.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ42080.1 - 0.0058 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.5 KEZ42080.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 KR domain Pyr_redox PF00070.22 KEZ42080.1 - 0.043 14.2 0.0 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ42080.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KEZ42081.1 - 2e-15 56.7 0.1 2.6e-14 53.0 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ42081.1 - 2e-10 40.1 7.0 2.2e-05 23.5 0.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KEZ42081.1 - 1.3e-06 27.3 0.0 0.028 13.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.7 KEZ42081.1 - 3.3e-06 26.2 0.5 0.0044 15.9 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ42081.1 - 3.5e-06 26.9 0.1 1.4e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEZ42081.1 - 6.8e-06 25.9 0.2 6.2e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEZ42081.1 - 2.8e-05 23.1 0.5 7.8e-05 21.6 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEZ42081.1 - 0.00013 22.2 0.3 0.0012 19.2 0.2 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ42081.1 - 0.00019 21.3 0.3 0.00044 20.1 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ42081.1 - 0.0012 17.4 0.2 0.017 13.6 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KEZ42081.1 - 0.0095 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ42081.1 - 0.023 13.8 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KEZ42081.1 - 0.039 13.0 1.2 0.085 11.9 0.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.17 KEZ42082.1 - 5.8e-57 193.2 0.0 1.3e-52 178.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.14 KEZ42083.1 - 1.8e-20 73.2 0.8 4.4e-20 72.0 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.6 KEZ42083.1 - 4.8e-12 45.7 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.9 KEZ42083.1 - 8e-07 29.1 0.2 3.2e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ42083.1 - 2.3e-06 27.5 0.1 7.1e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ42083.1 - 5.6e-06 25.4 0.2 1.1e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KEZ42083.1 - 8.7e-05 21.5 3.6 0.0002 20.4 2.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ42083.1 - 0.0031 17.5 0.1 0.0088 16.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ42083.1 - 0.0042 16.0 0.0 0.0061 15.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KEZ42083.1 - 0.0067 14.9 0.0 0.0098 14.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KEZ42083.1 - 0.0077 16.6 0.2 0.028 14.8 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ42083.1 - 0.011 14.6 0.1 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 KEZ42083.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KEZ42083.1 - 0.019 13.6 0.9 0.055 12.0 0.3 1.8 1 1 1 2 2 2 0 Tryptophan halogenase AMP-binding PF00501.23 KEZ42085.1 - 0 1448.4 0.5 1.6e-78 263.9 0.0 6.4 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 KEZ42085.1 - 7.9e-295 973.8 0.0 3.3e-59 200.1 0.0 8.3 8 0 0 8 8 8 8 Condensation domain PP-binding PF00550.20 KEZ42085.1 - 6.5e-78 256.9 1.7 6.4e-12 45.5 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KEZ42085.1 - 2.5e-42 143.0 0.5 1.6e-20 73.1 0.0 4.1 4 0 0 4 4 4 2 HxxPF-repeated domain AMP-binding_C PF13193.1 KEZ42085.1 - 8.8e-29 100.2 2.8 4.7e-10 40.2 0.0 5.4 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KEZ42085.1 - 5.8e-05 21.8 0.2 3.1 6.2 0.0 4.8 6 0 0 6 6 6 2 GH3 auxin-responsive promoter AATase PF07247.7 KEZ42085.1 - 0.00065 18.3 0.7 0.91 7.9 0.1 3.6 4 1 0 4 4 4 2 Alcohol acetyltransferase Nse5 PF08691.5 KEZ42085.1 - 0.26 9.7 0.0 0.43 9.0 0.0 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 AntA PF08346.7 KEZ42085.1 - 0.26 11.5 0.1 2 8.6 0.1 2.3 2 0 0 2 2 2 0 AntA/AntB antirepressor PID_2 PF14719.1 KEZ42085.1 - 0.9 9.1 0.1 4 7.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) VCBS PF13517.1 KEZ42086.1 - 8.6e-37 125.3 60.3 7.8e-12 45.3 0.8 7.5 2 2 5 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEZ42086.1 - 8.3e-16 57.1 27.8 0.0015 18.1 0.4 7.2 6 0 0 6 6 6 6 FG-GAP repeat Lipase_GDSL PF00657.17 KEZ42086.1 - 5.7e-14 52.5 0.2 1.2e-13 51.4 0.2 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ42086.1 - 9.1e-11 42.2 0.1 2.1e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KEZ42086.1 - 1.3e-07 31.5 0.0 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 KEZ42086.1 - 0.0043 16.5 16.4 1.3 8.4 0.0 5.8 6 1 2 8 8 8 4 Insecticide toxin TcdB middle/N-terminal region Abhydrolase_3 PF07859.8 KEZ42087.1 - 8.3e-41 139.8 0.0 1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KEZ42087.1 - 0.0012 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.23 KEZ42087.1 - 0.0022 16.8 0.0 0.0042 15.8 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KEZ42087.1 - 0.008 15.4 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family SHMT PF00464.14 KEZ42088.1 - 9.5e-200 663.0 0.0 1.1e-199 662.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KEZ42088.1 - 0.0036 16.5 0.0 0.0062 15.7 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase adh_short PF00106.20 KEZ42089.1 - 2.9e-26 92.3 0.0 4.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ42089.1 - 3.5e-09 36.5 0.0 1e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ42089.1 - 4.9e-06 26.1 0.0 1.8e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEZ42089.1 - 3.3e-05 22.7 0.0 5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.1 KEZ42089.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ42089.1 - 0.017 15.1 0.0 0.14 12.1 0.0 2.2 3 0 0 3 3 3 0 NADH(P)-binding FAD_binding_3 PF01494.14 KEZ42090.1 - 3.6e-77 259.8 0.0 4.5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEZ42090.1 - 9e-36 123.0 0.0 1.5e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 KEZ42090.1 - 4.4e-05 22.5 2.1 0.0026 16.7 0.2 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ42090.1 - 0.0002 20.3 0.3 0.0011 17.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 KEZ42090.1 - 0.0012 17.9 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KEZ42090.1 - 0.0017 17.5 0.4 0.0036 16.4 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ42090.1 - 0.0032 17.5 0.4 0.031 14.3 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KEZ42090.1 - 0.0051 15.6 0.0 0.019 13.8 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 KEZ42090.1 - 0.042 13.8 0.3 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3023 PF11224.3 KEZ42090.1 - 0.085 12.5 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3023) Arylsulfotran_2 PF14269.1 KEZ42091.1 - 5e-54 183.4 0.1 3.2e-52 177.5 0.1 2.3 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KEZ42091.1 - 3.8e-20 71.8 0.1 2.3e-19 69.2 0.1 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) AMP-binding PF00501.23 KEZ42092.1 - 1e-68 231.6 0.0 3.2e-37 127.9 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ42092.1 - 8.5e-08 33.0 0.1 2.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cytochrom_B561 PF03188.11 KEZ42092.1 - 0.03 14.1 1.3 0.072 12.9 0.9 1.7 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Sulfatase PF00884.18 KEZ42094.1 - 4.1e-74 249.5 0.0 5.2e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KEZ42094.1 - 0.0077 14.6 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 KEZ42094.1 - 0.014 14.7 0.1 0.049 12.9 0.0 2.0 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KEZ42094.1 - 0.047 13.9 0.0 0.64 10.3 0.0 2.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Alpha_E1_glycop PF01589.11 KEZ42095.1 - 0.15 10.3 0.1 0.31 9.3 0.0 1.4 2 0 0 2 2 2 0 Alphavirus E1 glycoprotein Sugar_tr PF00083.19 KEZ42096.1 - 4.4e-95 318.8 22.0 5.2e-95 318.6 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42096.1 - 1.9e-14 53.1 25.8 1.9e-14 53.1 17.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KEZ42097.1 - 2e-36 125.4 48.2 5.4e-28 97.7 18.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ42097.1 - 0.00015 20.3 21.1 0.0026 16.2 2.7 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 KEZ42097.1 - 0.0027 17.4 6.2 1.3 8.8 0.2 4.1 3 2 1 4 4 4 2 MFS_1 like family ATG22 PF11700.3 KEZ42097.1 - 0.0087 14.5 21.1 0.12 10.8 6.2 2.4 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 KEZ42097.1 - 0.36 9.3 21.7 0.053 12.1 6.2 3.3 2 2 1 3 3 3 0 Sugar (and other) transporter MR_MLE_C PF13378.1 KEZ42098.1 - 3.3e-32 110.7 0.1 6.8e-32 109.7 0.1 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KEZ42098.1 - 6.3e-23 81.0 0.0 1.3e-21 76.7 0.0 2.3 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KEZ42098.1 - 8.7e-11 42.2 0.0 2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MFS_1 PF07690.11 KEZ42099.1 - 2.7e-28 98.7 41.4 1.7e-19 69.7 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ42099.1 - 9.7e-05 20.7 2.1 0.0007 17.9 0.2 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_10 PF00331.15 KEZ42100.1 - 2.1e-80 270.1 0.1 2.3e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 KEZ42100.1 - 0.096 13.1 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like Glyco_hydro_3 PF00933.16 KEZ42101.1 - 3e-55 187.3 0.1 5.2e-43 147.1 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ42101.1 - 8.3e-19 68.0 0.1 8.9e-13 48.2 0.0 3.2 2 1 1 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Sugar_tr PF00083.19 KEZ42102.1 - 1.9e-84 283.8 19.9 2.2e-84 283.6 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42102.1 - 6.5e-23 80.9 51.5 1.4e-19 70.0 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1774 PF08611.5 KEZ42102.1 - 0.017 15.2 2.1 0.079 13.1 0.1 2.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Glyco_hydro_42 PF02449.10 KEZ42103.1 - 1.2e-09 37.7 0.1 2.6e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 KEZ42103.1 - 0.00019 20.8 0.0 0.00062 19.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 HTH_21 PF13276.1 KEZ42103.1 - 0.11 12.5 0.1 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain Glyco_hydro_1 PF00232.13 KEZ42104.1 - 7.3e-16 57.4 0.0 8.7e-08 30.7 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 RTA1 PF04479.8 KEZ42105.1 - 9.8e-34 116.7 7.8 1.8e-33 115.9 5.4 1.4 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 KEZ42105.1 - 0.0013 17.4 0.9 0.0013 17.4 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain GP41 PF00517.12 KEZ42105.1 - 0.22 11.0 0.1 0.22 11.0 0.1 2.5 2 1 1 3 3 3 0 Retroviral envelope protein CemA PF03040.9 KEZ42105.1 - 1.4 8.4 7.6 0.079 12.5 1.2 1.9 2 0 0 2 2 2 0 CemA family Abhydrolase_9_N PF15420.1 KEZ42105.1 - 4.4 7.0 9.8 0.28 10.9 2.2 2.1 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Hydrophobin PF01185.13 KEZ42106.1 - 1.2e-11 44.8 6.5 2.2e-11 44.0 4.5 1.5 1 0 0 1 1 1 1 Fungal hydrophobin Med3 PF11593.3 KEZ42106.1 - 0.076 12.2 2.7 0.089 12.0 1.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TMP-TENI PF02581.12 KEZ42106.1 - 0.079 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI p450 PF00067.17 KEZ42107.1 - 1e-51 175.9 0.0 1.5e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S13 PF02113.10 KEZ42108.1 - 7.5e-92 308.1 0.0 9.1e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Peptidase_S11 PF00768.15 KEZ42108.1 - 6.8e-05 22.2 0.0 0.00056 19.2 0.0 2.0 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Cadherin-like PF12733.2 KEZ42108.1 - 0.095 12.9 0.1 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain Fringe PF02434.11 KEZ42109.1 - 4.1e-05 22.9 0.5 0.00042 19.6 0.4 2.3 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 KEZ42109.1 - 0.011 15.3 0.4 0.034 13.8 0.3 1.8 1 0 0 1 1 1 0 PAN domain Galactosyl_T PF01762.16 KEZ42109.1 - 0.048 13.2 0.0 0.15 11.6 0.0 1.8 1 1 1 2 2 2 0 Galactosyltransferase PAN_2 PF08276.6 KEZ42109.1 - 0.061 13.1 0.5 0.19 11.6 0.4 1.8 1 0 0 1 1 1 0 PAN-like domain Glyco_hydro_61 PF03443.9 KEZ42111.1 - 6.7e-44 150.2 0.0 7.6e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 KEZ42112.1 - 6.8e-23 80.9 7.8 8.6e-23 80.6 5.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 KEZ42113.1 - 1.7e-54 185.2 0.6 2.4e-54 184.7 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 KEZ42114.1 - 1.1e-30 106.6 13.9 1.3e-30 106.3 9.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42114.1 - 3.1e-10 39.3 18.0 5e-10 38.6 12.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ42114.1 - 0.0042 15.3 2.4 0.0049 15.1 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YrvL PF14184.1 KEZ42114.1 - 0.076 12.8 2.6 1.8 8.3 0.5 2.3 2 0 0 2 2 2 0 Regulatory protein YrvL Tropomyosin PF00261.15 KEZ42115.1 - 0.077 12.0 1.1 0.13 11.3 0.8 1.2 1 0 0 1 1 1 0 Tropomyosin DUF946 PF06101.6 KEZ42116.1 - 4.1e-13 48.1 0.8 1.7e-11 42.8 0.2 2.1 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) Helicase_C PF00271.26 KEZ42117.1 - 7.4e-12 44.9 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KEZ42117.1 - 4.1e-11 42.2 0.0 1.6e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_5 PF14634.1 KEZ42117.1 - 0.00017 21.2 3.0 0.00034 20.2 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ42117.1 - 0.0021 17.8 2.9 0.0044 16.8 2.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEZ42117.1 - 0.012 15.2 2.7 0.028 14.0 1.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEZ42117.1 - 0.043 13.6 4.0 0.092 12.6 1.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KEZ42117.1 - 0.074 13.0 3.1 0.22 11.5 2.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEZ42117.1 - 0.83 9.2 4.2 1.9 8.1 2.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NACHT PF05729.7 KEZ42118.1 - 1.4e-08 34.5 0.1 3.8e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 KEZ42118.1 - 4e-08 33.5 0.0 0.0033 17.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) AAA_22 PF13401.1 KEZ42118.1 - 1.6e-07 31.5 0.1 4.9e-06 26.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.1 KEZ42118.1 - 6.8e-06 25.8 0.0 0.013 15.7 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KEZ42118.1 - 1.2e-05 24.8 0.2 0.0046 16.7 0.0 3.9 4 0 0 4 4 3 1 Ankyrin repeat Ank_5 PF13857.1 KEZ42118.1 - 1.9e-05 24.7 0.0 0.013 15.6 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) KaiC PF06745.8 KEZ42118.1 - 0.00013 21.1 0.3 0.00036 19.7 0.0 1.8 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.17 KEZ42118.1 - 0.00018 20.4 0.1 0.0021 16.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Ank_4 PF13637.1 KEZ42118.1 - 0.0016 18.8 0.1 1.1 9.9 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 KEZ42118.1 - 0.0041 17.1 0.0 0.026 14.5 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain Na_sulph_symp PF00939.14 KEZ42118.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region IstB_IS21 PF01695.12 KEZ42118.1 - 0.017 14.5 0.1 0.084 12.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KEZ42118.1 - 0.029 13.4 0.0 0.077 12.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 KEZ42118.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ42118.1 - 0.048 14.4 0.7 2.2 9.0 0.0 3.5 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 KEZ42118.1 - 0.064 12.4 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 KEZ42118.1 - 0.13 12.1 1.2 0.47 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Cu_amine_oxid PF01179.15 KEZ42120.1 - 9.9e-36 123.3 0.0 1.1e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxid PF01179.15 KEZ42121.1 - 1.4e-32 113.0 0.2 1.7e-32 112.6 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain HNH_2 PF13391.1 KEZ42121.1 - 2.8e-07 30.2 0.1 6.9e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease Clr5 PF14420.1 KEZ42122.1 - 7e-13 48.2 1.5 1e-12 47.7 1.0 1.2 1 0 0 1 1 1 1 Clr5 domain Sugar_tr PF00083.19 KEZ42123.1 - 7.2e-23 80.8 26.8 1.3e-13 50.3 7.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Amidase PF01425.16 KEZ42124.1 - 2.5e-40 138.7 0.0 2.7e-21 75.9 0.0 2.1 1 1 1 2 2 2 2 Amidase Isochorismatase PF00857.15 KEZ42124.1 - 1.4e-34 119.5 0.0 3.1e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Fructosamin_kin PF03881.9 KEZ42125.1 - 1.5e-43 148.8 0.0 1.9e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEZ42125.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3176 PF11374.3 KEZ42126.1 - 4.7e-27 94.0 1.4 8e-27 93.3 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Ank_2 PF12796.2 KEZ42127.1 - 1.4e-29 102.2 0.0 8.7e-06 25.9 0.0 5.4 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ42127.1 - 1.4e-24 84.6 7.8 3.2e-05 23.5 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KEZ42127.1 - 9.7e-23 77.9 0.4 0.023 14.9 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KEZ42127.1 - 5.1e-21 74.2 4.4 0.0035 17.5 0.1 6.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ42127.1 - 3.6e-19 68.7 3.2 0.00071 20.0 0.0 8.0 6 1 2 8 8 8 6 Ankyrin repeats (many copies) NCU-G1 PF15065.1 KEZ42128.1 - 0.043 12.5 0.7 0.07 11.8 0.5 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 HET PF06985.6 KEZ42130.1 - 7.6e-12 45.5 0.0 2.4e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1054 PF06335.7 KEZ42130.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Helicase_C PF00271.26 KEZ42131.1 - 4.2e-06 26.5 0.2 9.2e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ42132.1 - 2.8e-17 62.7 0.0 4.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEZ42132.1 - 1.4e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KEZ42132.1 - 0.033 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein FAA_hydrolase PF01557.13 KEZ42133.1 - 1.6e-59 200.9 0.0 2.7e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 KEZ42133.1 - 1.3e-42 146.2 2.7 1.9e-42 145.6 1.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ42133.1 - 8.4e-19 68.0 0.0 5.5e-18 65.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ42133.1 - 9.7e-19 67.5 0.1 2.8e-18 66.0 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KEZ42133.1 - 3.1e-11 43.1 0.4 3.6e-08 33.2 1.0 2.3 1 1 1 2 2 2 2 Serine hydrolase Hydrolase_4 PF12146.3 KEZ42133.1 - 0.0014 18.4 0.1 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 KEZ42133.1 - 0.0023 16.4 0.0 0.0032 16.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 KEZ42133.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Na_H_Exchanger PF00999.16 KEZ42134.1 - 1.8e-40 138.6 16.2 2.1e-40 138.4 11.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.3 KEZ42134.1 - 3.3 7.4 4.6 12 5.5 0.1 3.0 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TauD PF02668.11 KEZ42135.1 - 3.3e-37 128.5 0.0 4.4e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 KEZ42136.1 - 7.4e-86 288.4 22.8 8.5e-86 288.2 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42136.1 - 2.4e-29 102.1 22.3 2.4e-29 102.1 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ42136.1 - 4.2e-08 32.0 27.7 0.00035 19.0 5.1 3.4 2 2 1 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 KEZ42136.1 - 8.9e-05 20.8 1.3 8.9e-05 20.8 0.9 2.0 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF543 PF04418.7 KEZ42136.1 - 0.01 15.7 0.9 0.01 15.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) BT1 PF03092.11 KEZ42136.1 - 0.58 8.8 10.6 0.15 10.7 2.3 2.5 1 1 1 2 2 2 0 BT1 family HET PF06985.6 KEZ42137.1 - 1.3e-19 70.7 0.0 3.1e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 KEZ42138.1 - 6.8e-16 58.2 3.6 3.8e-15 55.7 0.5 2.5 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ42138.1 - 1.8e-06 27.8 0.1 4.6e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ42138.1 - 0.0001 21.3 5.0 0.00055 18.9 0.6 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ42138.1 - 0.00034 20.4 3.8 0.0011 18.7 0.9 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEZ42138.1 - 0.0023 17.8 0.4 0.0071 16.2 0.2 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ42138.1 - 0.0025 16.7 1.3 0.0025 16.7 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KEZ42138.1 - 0.0026 16.7 0.4 1.2 7.9 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.9 KEZ42138.1 - 0.0074 14.9 0.1 0.32 9.5 0.0 2.1 1 1 1 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 KEZ42138.1 - 0.011 14.2 0.2 0.02 13.3 0.2 1.5 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KEZ42138.1 - 0.011 15.7 0.2 0.026 14.5 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ42138.1 - 0.028 14.8 0.7 0.07 13.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ42138.1 - 0.28 10.2 0.9 0.82 8.7 0.1 2.0 2 1 1 3 3 3 0 Thi4 family CorA PF01544.13 KEZ42139.1 - 1.4e-07 30.8 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TBSV_P22 PF03558.8 KEZ42139.1 - 0.044 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 TBSV core protein P21/P22 Beta-lactamase PF00144.19 KEZ42140.1 - 3.2e-14 52.6 0.0 2.1e-12 46.7 0.0 2.3 2 1 0 2 2 2 2 Beta-lactamase PhzC-PhzF PF02567.11 KEZ42141.1 - 6.3e-42 143.7 0.0 7.9e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TSP_C PF05735.7 KEZ42141.1 - 0.16 11.4 0.1 0.41 10.1 0.0 1.6 2 0 0 2 2 2 0 Thrombospondin C-terminal region OTT_1508_deam PF14441.1 KEZ42142.1 - 1.6e-17 63.6 0.1 4.2e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 OTT_1508-like deaminase PLA2_B PF01735.13 KEZ42144.1 - 4.1e-169 562.8 0.0 4.8e-169 562.6 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MFS_1 PF07690.11 KEZ42145.1 - 4.1e-37 127.7 54.5 5.6e-37 127.2 37.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-MYND PF01753.13 KEZ42146.1 - 3.3e-06 26.8 2.8 7.7e-06 25.6 2.0 1.6 1 0 0 1 1 1 1 MYND finger DUF3787 PF12655.2 KEZ42147.1 - 0.019 14.6 0.6 0.034 13.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) DUF3864 PF12980.2 KEZ42147.1 - 0.065 13.4 0.3 0.76 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) TPR_12 PF13424.1 KEZ42149.1 - 3.1e-13 49.4 10.4 7.1e-06 25.8 2.5 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ42149.1 - 3.5e-12 45.8 17.9 0.0013 18.6 0.5 5.5 5 1 1 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ42149.1 - 3e-10 39.4 0.0 5.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEZ42149.1 - 2.2e-07 31.0 0.0 7.7e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Apc3 PF12895.2 KEZ42149.1 - 1.6e-05 24.9 2.5 0.0046 17.0 0.9 3.3 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Patatin PF01734.17 KEZ42149.1 - 2.3e-05 24.4 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_16 PF13432.1 KEZ42149.1 - 0.00025 21.6 8.2 2.2 9.0 0.4 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ42149.1 - 0.00061 19.3 12.2 0.55 10.1 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.1 KEZ42149.1 - 0.0027 17.6 1.4 0.011 15.7 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.12 KEZ42149.1 - 0.0038 17.0 4.2 35 4.6 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ42149.1 - 0.0052 17.1 0.0 21 5.8 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2469 PF10611.4 KEZ42149.1 - 0.011 16.1 10.3 3.3 8.1 0.1 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF2469) WD40 PF00400.27 KEZ42149.1 - 0.015 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat NACHT PF05729.7 KEZ42149.1 - 0.027 14.1 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_19 PF14559.1 KEZ42149.1 - 0.033 14.5 7.2 1 9.7 0.8 4.6 2 1 3 5 5 5 0 Tetratricopeptide repeat DUF1446 PF07287.6 KEZ42149.1 - 0.045 12.2 0.7 16 3.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1446) Paf67 PF10255.4 KEZ42149.1 - 0.048 12.5 0.1 14 4.4 0.0 3.1 1 1 1 3 3 3 0 RNA polymerase I-associated factor PAF67 TPR_20 PF14561.1 KEZ42149.1 - 0.069 13.2 7.1 14 5.8 0.6 4.2 1 1 3 4 4 4 0 Tetratricopeptide repeat NSs PF11073.3 KEZ42149.1 - 0.65 9.1 3.1 13 4.9 0.1 2.9 3 0 0 3 3 3 0 Rift valley fever virus non structural protein (NSs) like DUF2267 PF10025.4 KEZ42149.1 - 1.6 8.7 7.1 7.9 6.5 0.3 4.2 3 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) TPR_14 PF13428.1 KEZ42149.1 - 5.5 7.9 10.1 11 6.9 0.4 5.4 5 1 1 6 6 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 KEZ42151.1 - 1e-12 48.2 2.1 2e-10 40.8 0.0 3.6 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ42151.1 - 6.3e-12 44.6 0.2 6.6e-05 22.5 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEZ42151.1 - 1.3e-10 41.4 0.1 1.1e-06 28.9 0.1 3.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ42151.1 - 4.2e-08 33.1 0.2 4.6e-06 26.6 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ42151.1 - 1.1e-07 31.3 0.2 0.0027 17.8 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat PRTase_2 PF15609.1 KEZ42151.1 - 0.097 11.9 1.1 0.16 11.2 0.8 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Ank_2 PF12796.2 KEZ42152.1 - 5.9e-47 157.9 3.9 2.1e-12 47.1 0.1 6.8 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ42152.1 - 1.2e-44 149.8 7.9 4.5e-10 39.7 0.0 10.3 7 4 4 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.25 KEZ42152.1 - 1.1e-39 132.2 12.3 6.9e-09 35.0 0.0 11.5 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.1 KEZ42152.1 - 7.1e-35 118.2 14.6 5.4e-09 35.9 0.0 8.1 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Fungal_trans PF04082.13 KEZ42152.1 - 1.4e-25 89.6 0.3 2.9e-25 88.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_3 PF13606.1 KEZ42152.1 - 1.7e-22 77.1 11.2 6.4e-05 22.8 0.0 11.1 12 0 0 12 12 10 3 Ankyrin repeat GST_N PF02798.15 KEZ42152.1 - 1.1e-14 54.3 0.0 2.4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEZ42152.1 - 5.5e-14 51.9 0.0 1.9e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ42152.1 - 2.9e-12 46.6 0.0 3.4e-11 43.2 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEZ42152.1 - 1.4e-11 44.1 0.0 3.8e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NACHT PF05729.7 KEZ42152.1 - 6e-07 29.2 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain GST_C_2 PF13410.1 KEZ42152.1 - 1.7e-05 24.6 0.0 6.7e-05 22.6 0.0 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEZ42152.1 - 0.00028 21.3 0.0 0.0011 19.3 0.0 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AAA_22 PF13401.1 KEZ42152.1 - 0.00038 20.6 0.1 0.0023 18.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain adh_short_C2 PF13561.1 KEZ42153.1 - 2.1e-30 106.2 0.0 2.7e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ42153.1 - 8.7e-24 84.3 0.1 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ42153.1 - 2.5e-10 40.3 0.0 6e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEZ42153.1 - 9.6e-05 21.9 0.1 0.00027 20.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 KEZ42154.1 - 8.3e-22 78.2 0.0 2.3e-21 76.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ42154.1 - 5.4e-18 64.5 0.1 9.8e-16 57.0 0.1 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ42154.1 - 1.8e-07 31.0 0.0 5.4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ42154.1 - 1.8e-06 27.1 0.0 0.001 18.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEZ42154.1 - 0.00015 21.6 0.0 0.2 11.4 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ42154.1 - 0.0061 16.3 0.1 0.21 11.3 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KEZ42154.1 - 0.019 15.3 0.1 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KEZ42154.1 - 0.027 14.5 0.0 0.85 9.7 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 KEZ42154.1 - 0.082 12.4 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.11 KEZ42155.1 - 4.3e-36 124.3 14.7 4.3e-36 124.3 10.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ42155.1 - 1.5e-09 36.9 14.3 3.7e-09 35.6 9.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DHDPS PF00701.17 KEZ42156.1 - 9.2e-44 149.1 0.0 1.1e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 KEZ42156.1 - 0.00067 18.9 0.0 0.00095 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.11 KEZ42157.1 - 1.9e-36 125.5 18.7 3.1e-36 124.8 12.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sulf_coat_C PF12193.3 KEZ42157.1 - 0.073 12.8 0.2 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal PhyH PF05721.8 KEZ42158.1 - 2.7e-12 47.1 0.0 6.4e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.20 KEZ42159.1 - 2.3e-18 66.6 4.9 1.5e-17 63.9 3.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ42159.1 - 1.4e-15 57.7 0.1 3.6e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ42159.1 - 8.7e-08 32.0 1.9 1.3e-07 31.4 0.5 1.8 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KEZ42159.1 - 0.00055 19.9 1.5 0.001 19.0 1.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 KEZ42159.1 - 0.017 14.7 1.5 0.024 14.2 1.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KEZ42159.1 - 0.037 13.4 0.6 0.15 11.4 0.2 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family LPP PF04728.8 KEZ42159.1 - 0.037 13.8 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Trns_repr_metal PF02583.12 KEZ42159.1 - 0.13 12.5 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Ank PF00023.25 KEZ42160.1 - 4e-18 64.2 1.9 1.1e-07 31.3 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEZ42160.1 - 9.1e-18 64.3 0.0 4e-17 62.3 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEZ42160.1 - 1.2e-14 53.9 0.3 1.5e-08 34.5 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ42160.1 - 1.1e-11 43.7 0.2 4.1e-05 23.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KEZ42160.1 - 1.4e-10 41.4 0.1 6e-05 23.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TyeA PF09059.5 KEZ42160.1 - 0.0072 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 TyeA NACHT PF05729.7 KEZ42160.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MFS_1 PF07690.11 KEZ42161.1 - 2.5e-23 82.3 48.2 6.9e-23 80.9 33.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Rotamase_2 PF13145.1 KEZ42162.1 - 0.001 19.7 0.1 0.0017 18.9 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain CorA PF01544.13 KEZ42162.1 - 0.002 17.1 0.4 0.0034 16.4 0.0 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein FAD_binding_4 PF01565.18 KEZ42163.1 - 3.2e-15 55.8 2.4 6.1e-14 51.6 1.7 2.5 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ42163.1 - 7.7e-11 41.7 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KEZ42163.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF1748 PF08520.5 KEZ42164.1 - 0.019 14.6 0.0 0.034 13.7 0.0 1.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) Fungal_trans PF04082.13 KEZ42166.1 - 6e-13 48.2 3.1 8.3e-13 47.7 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.16 KEZ42167.1 - 4.5e-59 200.4 1.8 9.7e-59 199.3 1.2 1.5 1 1 0 1 1 1 1 Amidase adh_short_C2 PF13561.1 KEZ42167.1 - 4.3e-06 26.6 0.0 8.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 KEZ42168.1 - 2.2e-56 191.3 0.0 2.6e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KEZ42169.1 - 2.1e-58 197.3 0.0 3.3e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KEZ42169.1 - 4e-23 81.9 0.0 7.4e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KEZ42169.1 - 1.7e-21 76.8 0.0 6.2e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain AA_permease PF00324.16 KEZ42170.1 - 4.3e-75 252.8 33.8 5e-75 252.6 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ42170.1 - 2.2e-20 72.6 34.9 2.6e-20 72.3 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease RRM_6 PF14259.1 KEZ42173.1 - 6.6e-09 35.6 0.1 2e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ42173.1 - 8.3e-09 34.9 0.4 1.7e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ42173.1 - 0.00032 20.4 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PAP1 PF08601.5 KEZ42173.1 - 0.0087 15.7 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 HTH_45 PF14947.1 KEZ42173.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix Cadherin-like PF12733.2 KEZ42173.1 - 0.13 12.5 0.9 0.24 11.7 0.2 1.7 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain Fer2_BFD PF04324.10 KEZ42174.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain FAM220 PF15487.1 KEZ42174.1 - 1.4 8.2 8.3 2.5 7.3 5.8 1.4 1 0 0 1 1 1 0 FAM220 family AA_permease_2 PF13520.1 KEZ42175.1 - 1.1e-58 198.7 17.6 2.3e-58 197.7 12.2 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ42175.1 - 3.2e-15 55.4 8.0 3.2e-15 55.4 5.5 1.9 2 0 0 2 2 2 1 Amino acid permease SNARE_assoc PF09335.6 KEZ42175.1 - 3.8 7.7 26.1 0.28 11.3 1.1 4.5 5 1 0 5 5 5 0 SNARE associated Golgi protein NACHT PF05729.7 KEZ42176.1 - 2.5e-11 43.5 0.2 8.1e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEZ42176.1 - 7.7e-06 26.0 3.9 1.1e-05 25.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ42176.1 - 0.00017 21.7 0.2 0.0012 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEZ42176.1 - 0.0063 15.9 1.2 0.088 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain RNA_helicase PF00910.17 KEZ42176.1 - 0.02 15.0 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 KEZ42176.1 - 0.027 14.7 0.9 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 KEZ42176.1 - 0.038 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KEZ42176.1 - 0.048 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KEZ42176.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KEZ42176.1 - 0.085 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 KEZ42176.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.7 2 1 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.12 KEZ42176.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 KEZ42176.1 - 0.21 11.0 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KEZ42176.1 - 0.39 11.5 3.4 1.3 9.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain DUF4404 PF14357.1 KEZ42176.1 - 2.9 8.3 10.7 0.73 10.2 2.2 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) Zip PF02535.17 KEZ42177.1 - 1.9e-46 158.5 1.2 3e-46 157.8 0.8 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Striatin PF08232.7 KEZ42178.1 - 0.023 14.9 0.4 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Striatin family DUF2051 PF09738.4 KEZ42178.1 - 0.063 12.5 2.8 0.38 10.0 0.2 2.2 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) DUF2046 PF09755.4 KEZ42178.1 - 0.12 11.2 0.1 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Cyto_heme_lyase PF01265.12 KEZ42179.1 - 9.3e-78 261.3 0.0 3e-77 259.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase AcetylCoA_hydro PF02550.10 KEZ42181.1 - 6e-46 156.7 0.0 9.4e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KEZ42181.1 - 5.1e-39 133.4 0.0 8.2e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 KEZ42181.1 - 0.1 11.7 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 Coenzyme A transferase DUF3433 PF11915.3 KEZ42182.1 - 7.9e-15 54.8 17.5 1.1e-09 38.2 2.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Herpes_gE PF02480.11 KEZ42182.1 - 0.088 11.0 0.7 0.16 10.1 0.2 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF592 PF04574.8 KEZ42182.1 - 0.33 10.4 0.0 0.57 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF592) SET PF00856.23 KEZ42184.1 - 4.9e-11 43.2 0.2 2.3e-10 41.0 0.1 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KEZ42184.1 - 1.4e-07 31.2 16.9 4.2e-07 29.7 11.7 1.9 1 0 0 1 1 1 1 MYND finger DUF2304 PF10066.4 KEZ42186.1 - 2.2 8.1 11.1 2.8 7.8 6.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) 4HBT PF03061.17 KEZ42187.1 - 8.2e-15 54.6 0.9 1.3e-14 54.0 0.6 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KEZ42187.1 - 4e-05 23.5 0.1 4.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 KEZ42187.1 - 0.0048 16.6 0.1 0.0053 16.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Tfb2 PF03849.9 KEZ42188.1 - 5e-129 430.0 0.0 6.3e-129 429.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KEZ42188.1 - 6.6e-07 29.1 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 KEZ42188.1 - 0.021 14.2 0.2 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 Anti-repressor SinI TB2_DP1_HVA22 PF03134.14 KEZ42190.1 - 9e-31 105.4 8.7 1.3e-30 104.9 6.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.7 KEZ42191.1 - 1.7e-82 274.8 0.0 2.2e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 eIF-1a PF01176.14 KEZ42191.1 - 0.041 13.2 0.0 0.096 12.1 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 CHCH PF06747.8 KEZ42192.1 - 0.00036 20.3 3.9 0.00076 19.3 2.5 1.7 1 1 0 1 1 1 1 CHCH domain DUF3295 PF11702.3 KEZ42192.1 - 0.046 12.7 1.7 0.047 12.6 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF2169 PF09937.4 KEZ42192.1 - 0.089 11.8 0.4 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Imm33 PF15580.1 KEZ42192.1 - 0.13 11.7 1.6 0.17 11.4 1.1 1.3 1 0 0 1 1 1 0 Immunity protein 33 BPL_N PF09825.4 KEZ42193.1 - 2.4e-141 470.7 0.0 2.9e-141 470.5 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KEZ42193.1 - 6.2e-20 71.4 0.0 1.2e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KEZ42193.1 - 0.045 13.4 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Syndecan PF01034.15 KEZ42195.1 - 0.062 12.9 0.3 0.2 11.3 0.2 1.8 1 0 0 1 1 1 0 Syndecan domain Pam16 PF03656.8 KEZ42196.1 - 6e-33 113.3 0.1 7.8e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Pam16 Yip1 PF04893.12 KEZ42197.1 - 2.6e-07 30.3 12.2 0.0001 21.8 4.6 2.4 2 0 0 2 2 2 2 Yip1 domain DUF1096 PF06493.6 KEZ42198.1 - 2.4 8.2 42.5 1.9 8.5 3.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1096) Chitin_bind_3 PF03067.10 KEZ42199.1 - 2.7e-07 31.0 0.0 4.3e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Chitin binding domain OTT_1508_deam PF14441.1 KEZ42200.1 - 1.5e-08 34.5 0.1 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase PSP PF04046.11 KEZ42200.1 - 0.02 14.2 1.3 0.044 13.1 0.1 2.1 2 0 0 2 2 2 0 PSP Glyco_hydro_67M PF07488.7 KEZ42201.1 - 3.9e-149 495.9 0.0 5.3e-149 495.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KEZ42201.1 - 3e-91 304.8 2.3 4.5e-91 304.2 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KEZ42201.1 - 8.5e-28 96.8 0.0 1.5e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus PAP_assoc PF03828.14 KEZ42202.1 - 9.6e-14 51.0 0.1 2.2e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KEZ42202.1 - 2.7e-07 30.8 0.1 8.1e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain TROVE PF05731.6 KEZ42202.1 - 0.082 11.6 2.1 0.13 11.0 1.5 1.2 1 0 0 1 1 1 0 TROVE domain DUF4611 PF15387.1 KEZ42202.1 - 0.94 9.6 12.6 0.035 14.2 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Glyco_hydro_61 PF03443.9 KEZ42203.1 - 3.2e-51 174.2 0.0 3.2e-51 174.2 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KEZ42203.1 - 1.6e-09 37.2 15.7 1.6e-09 37.2 10.9 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 KEZ42204.1 - 2.7e-14 53.5 0.2 3.8e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RAP1 PF07218.6 KEZ42205.1 - 1.5 6.8 2.6 1.9 6.4 1.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 KEZ42205.1 - 2.4 6.3 7.3 4.2 5.5 5.1 1.3 1 0 0 1 1 1 0 Transmembrane protein APH PF01636.18 KEZ42206.1 - 2.1e-09 37.4 0.6 6.1e-09 35.9 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ42206.1 - 0.00097 18.7 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase CHASE PF03924.8 KEZ42206.1 - 0.084 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 CHASE domain Atg14 PF10186.4 KEZ42208.1 - 0.39 9.6 12.9 0.65 8.8 9.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 KEZ42209.1 - 3.9e-17 62.2 0.0 6.2e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42209.1 - 8e-09 34.9 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ42209.1 - 0.00053 19.8 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KEZ42209.1 - 0.25 10.1 0.0 0.38 9.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1295 PF06966.7 KEZ42210.1 - 1.3e-12 47.5 0.0 2.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Fungal_trans PF04082.13 KEZ42210.1 - 8.5e-06 24.8 0.0 1.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Steroid_dh PF02544.11 KEZ42210.1 - 0.025 14.3 0.2 0.074 12.8 0.1 1.8 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase T4SS PF07996.6 KEZ42210.1 - 0.1 12.4 0.1 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins NmrA PF05368.8 KEZ42211.1 - 5.3e-57 192.7 0.7 7.1e-57 192.3 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ42211.1 - 1.4e-14 54.4 0.4 2.9e-14 53.4 0.2 1.6 1 1 1 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ42211.1 - 3.4e-06 25.9 0.1 4.6e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RTC PF01137.16 KEZ42211.1 - 0.097 11.4 0.1 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase Acetyltransf_7 PF13508.1 KEZ42212.1 - 0.0061 16.7 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEZ42212.1 - 0.02 15.0 0.0 4.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEZ42212.1 - 0.14 12.1 4.9 0.17 11.9 2.3 2.0 3 1 0 3 3 3 0 Acetyltransferase (GNAT) family Lipase_GDSL_2 PF13472.1 KEZ42213.1 - 0.0025 17.9 2.4 5.3 7.1 0.0 3.3 1 1 2 3 3 3 3 GDSL-like Lipase/Acylhydrolase family Lipocalin_5 PF13924.1 KEZ42214.1 - 7.7e-13 48.3 0.1 9.4e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 Lipocalin-like domain NUP PF06516.6 KEZ42215.1 - 2.4e-114 381.4 0.0 2.7e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.20 KEZ42216.1 - 6.9e-44 149.9 0.0 2.5e-43 148.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42216.1 - 1.2e-30 106.4 0.0 1.9e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42216.1 - 0.0086 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ42216.1 - 0.019 14.0 0.2 0.066 12.2 0.0 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_trans_3N PF02885.12 KEZ42216.1 - 0.17 11.4 0.0 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Pyr_redox_2 PF07992.9 KEZ42217.1 - 4.4e-28 98.5 0.2 5.6e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ42217.1 - 8.1e-17 61.4 0.1 4.6e-15 55.7 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ42217.1 - 6.9e-10 39.3 0.1 6.4e-07 29.6 0.0 2.9 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ42217.1 - 1.2e-05 24.4 0.5 0.66 8.8 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 KEZ42217.1 - 6.4e-05 21.9 1.8 0.86 8.3 0.0 4.0 3 1 1 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KEZ42217.1 - 9.3e-05 22.6 0.1 0.0014 18.8 0.0 2.4 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KEZ42217.1 - 0.00025 20.9 0.1 0.1 12.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ42217.1 - 0.00088 18.2 0.0 0.0028 16.6 0.0 1.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KEZ42217.1 - 0.0076 15.3 0.1 0.58 9.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KEZ42217.1 - 0.041 12.9 0.5 11 4.9 0.0 2.9 2 1 1 3 3 3 0 FAD binding domain FAD_binding_2 PF00890.19 KEZ42217.1 - 0.047 12.5 5.3 0.75 8.5 0.1 3.6 3 1 0 4 4 4 0 FAD binding domain Thi4 PF01946.12 KEZ42217.1 - 0.074 12.1 0.1 0.5 9.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 KEZ42217.1 - 0.12 12.4 0.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Vps53_N PF04100.7 KEZ42218.1 - 2.5e-101 339.2 0.3 4.6e-101 338.3 0.2 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 KEZ42218.1 - 8.7e-06 24.8 5.3 1.7e-05 23.8 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec6 PF06046.8 KEZ42218.1 - 6.7e-05 21.1 0.4 0.00056 18.1 0.0 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec6 Spc7 PF08317.6 KEZ42218.1 - 0.0014 17.3 1.1 0.0026 16.4 0.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Zw10 PF06248.8 KEZ42218.1 - 0.017 13.3 5.2 0.011 13.9 2.3 1.5 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF2451 PF10474.4 KEZ42218.1 - 0.024 14.4 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Amidase PF01425.16 KEZ42219.1 - 1.9e-88 297.2 0.0 2.4e-88 296.9 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1776 PF08643.5 KEZ42220.1 - 2.3e-100 335.5 0.0 3e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Methyltransf_31 PF13847.1 KEZ42220.1 - 7.7e-12 45.0 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42220.1 - 9.3e-11 42.0 0.0 1.9e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42220.1 - 9.1e-08 32.6 0.0 2.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ42220.1 - 7.1e-07 29.0 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42220.1 - 7.9e-07 29.4 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEZ42220.1 - 2.6e-06 27.1 0.0 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 KEZ42220.1 - 1.2e-05 25.3 0.0 3.8e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ42220.1 - 4.2e-05 23.8 0.0 9.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ42220.1 - 4.8e-05 22.8 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.13 KEZ42220.1 - 0.004 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 KEZ42220.1 - 0.019 14.1 0.1 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KEZ42220.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 KEZ42220.1 - 0.023 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 KEZ42220.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 KEZ42220.1 - 0.044 13.6 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase Ubie_methyltran PF01209.13 KEZ42220.1 - 0.11 11.6 0.0 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family zf-CCCH PF00642.19 KEZ42221.1 - 1e-09 37.8 6.0 2.2e-05 24.0 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEZ42221.1 - 0.055 13.4 9.6 0.43 10.6 1.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Scm3 PF10384.4 KEZ42222.1 - 1.8e-23 81.8 0.1 5.2e-23 80.2 0.0 1.9 1 0 0 1 1 1 1 Centromere protein Scm3 Pkinase PF00069.20 KEZ42223.1 - 1.5e-58 197.9 0.1 1.8e-58 197.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42223.1 - 1.5e-19 70.1 0.0 2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ42223.1 - 2e-08 34.2 0.0 8.9e-06 25.6 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ42223.1 - 0.0078 15.8 0.2 0.022 14.3 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KEZ42223.1 - 0.056 12.3 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KEZ42223.1 - 0.056 12.4 0.1 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Atg14 PF10186.4 KEZ42224.1 - 8.1e-66 222.0 0.0 9.5e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7_N PF15402.1 KEZ42226.1 - 2.3e-211 704.3 69.8 9.9e-112 374.6 24.8 2.1 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KEZ42226.1 - 9e-112 372.9 4.5 2.2e-111 371.6 3.1 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KEZ42226.1 - 2e-16 59.4 0.1 3.9e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 IncA PF04156.9 KEZ42226.1 - 4.5 6.8 16.2 0.085 12.4 5.4 2.5 2 0 0 2 2 2 0 IncA protein Ribosomal_S17 PF00366.15 KEZ42227.1 - 2.3e-30 104.4 3.8 3e-30 104.0 1.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 TACC PF05010.9 KEZ42228.1 - 0.0039 16.9 0.0 0.0069 16.1 0.0 1.3 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) Cmc1 PF08583.5 KEZ42228.1 - 0.32 10.7 3.9 0.89 9.3 2.7 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like ER_lumen_recept PF00810.13 KEZ42230.1 - 2.2e-37 128.8 10.5 3.4e-37 128.1 7.3 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KEZ42230.1 - 0.00049 19.5 1.8 0.024 14.1 0.0 3.1 2 1 0 2 2 2 1 PQ loop repeat DUF4181 PF13789.1 KEZ42230.1 - 1.4 8.9 9.7 0.19 11.6 3.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) RRM_1 PF00076.17 KEZ42231.1 - 7.8e-13 47.8 0.1 1.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ42231.1 - 2.5e-10 40.0 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ42231.1 - 5.9e-10 38.9 0.0 8.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PhoD PF09423.5 KEZ42232.1 - 0.047 12.2 0.0 0.076 11.5 0.0 1.3 1 0 0 1 1 1 0 PhoD-like phosphatase Peptidase_S8 PF00082.17 KEZ42233.1 - 8.8e-54 182.5 1.1 1.3e-53 182.0 0.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KEZ42233.1 - 3.2e-27 94.1 2.1 6e-27 93.2 1.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PepSY_TM_2 PF13703.1 KEZ42233.1 - 0.053 13.7 2.3 0.55 10.4 0.1 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix SCIMP PF15050.1 KEZ42233.1 - 0.076 12.9 0.4 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 SCIMP protein PX PF00787.19 KEZ42234.1 - 1.3e-20 73.2 0.6 1e-19 70.4 0.1 2.3 2 1 0 2 2 2 1 PX domain Vps5 PF09325.5 KEZ42234.1 - 7.1e-10 38.5 14.3 1.2e-06 27.9 1.7 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KEZ42234.1 - 5.3e-06 26.1 11.4 1.6e-05 24.5 7.9 1.7 1 1 0 1 1 1 1 BAR domain IncA PF04156.9 KEZ42234.1 - 0.003 17.1 1.9 0.003 17.1 1.3 2.3 2 0 0 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 KEZ42234.1 - 0.0069 15.6 0.2 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AlkA_N PF06029.6 KEZ42234.1 - 0.06 13.4 0.2 0.25 11.3 0.0 2.1 2 1 0 2 2 2 0 AlkA N-terminal domain DUF3140 PF11338.3 KEZ42234.1 - 0.072 13.2 0.8 0.34 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) DUF479 PF04336.7 KEZ42234.1 - 0.22 11.6 5.4 0.51 10.4 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function, DUF479 DUF1664 PF07889.7 KEZ42234.1 - 0.4 10.4 4.7 2.2 8.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CCT_2 PF09425.5 KEZ42234.1 - 0.54 9.8 4.3 3.8 7.1 0.4 2.5 2 0 0 2 2 2 0 Divergent CCT motif V_ATPase_I PF01496.14 KEZ42234.1 - 2.9 5.6 6.5 2.9 5.6 1.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ADK PF00406.17 KEZ42235.1 - 5.2e-38 130.2 0.0 3.1e-20 72.5 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 KEZ42235.1 - 3.6e-13 48.9 0.0 6.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 KEZ42235.1 - 1.9e-05 24.9 0.0 0.00035 20.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ42235.1 - 0.00014 22.6 0.0 0.00036 21.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEZ42235.1 - 0.00063 19.6 0.0 0.003 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEZ42235.1 - 0.048 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KEZ42235.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin LETM1 PF07766.8 KEZ42236.1 - 3.6e-105 350.8 1.5 5.8e-105 350.1 1.0 1.3 1 0 0 1 1 1 1 LETM1-like protein CTD PF12815.2 KEZ42236.1 - 1.6e-26 93.1 54.1 7.8e-20 71.5 26.0 4.6 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KEZ42236.1 - 2.2e-22 78.5 0.0 4.6e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KEZ42236.1 - 7.7e-16 58.5 8.3 7.7e-16 58.5 5.8 5.6 3 1 2 5 5 5 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KEZ42236.1 - 9.4e-06 25.1 20.9 0.0034 17.0 2.8 4.8 5 0 0 5 5 5 2 KOW motif SAP PF02037.22 KEZ42236.1 - 0.0011 18.4 0.0 0.038 13.5 0.0 3.0 3 0 0 3 3 3 1 SAP domain ATP-synt_ab_N PF02874.18 KEZ42236.1 - 0.049 13.8 2.1 0.22 11.7 0.2 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain TIR_2 PF13676.1 KEZ42236.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 TIR domain YajC PF02699.10 KEZ42236.1 - 0.56 9.9 6.1 1.6 8.4 0.1 3.7 3 0 0 3 3 3 0 Preprotein translocase subunit WD40 PF00400.27 KEZ42237.1 - 7.9e-23 79.4 7.2 1.6e-09 37.2 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF1748 PF08520.5 KEZ42238.1 - 1.2e-32 111.3 0.0 1.5e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 KEZ42239.1 - 7.3e-160 531.2 2.2 1e-159 530.8 1.5 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KEZ42239.1 - 1.5e-26 92.2 0.0 3.2e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.20 KEZ42239.1 - 0.00076 18.4 0.0 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain HpcH_HpaI PF03328.9 KEZ42239.1 - 0.0008 18.3 1.7 0.0019 17.1 0.3 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Glyco_hydro_61 PF03443.9 KEZ42240.1 - 3.9e-52 177.2 0.1 4.6e-52 176.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1768 PF08719.6 KEZ42241.1 - 2.3e-49 167.1 0.0 2.9e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.20 KEZ42242.1 - 1.4e-47 162.0 0.0 2e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KEZ42242.1 - 1.7e-43 144.9 24.0 1.7e-10 40.3 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 KEZ42242.1 - 2.7e-24 85.6 0.0 4.1e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Nup160 PF11715.3 KEZ42242.1 - 3.9e-05 21.9 8.3 0.52 8.3 0.1 5.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Kinase-like PF14531.1 KEZ42242.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 KEZ42242.1 - 0.081 11.7 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KEZ42242.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3312 PF11768.3 KEZ42242.1 - 0.19 9.9 0.0 0.36 8.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) UQ_con PF00179.21 KEZ42243.1 - 6.1e-47 158.5 0.0 7.1e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ42243.1 - 1.9e-05 24.4 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEZ42243.1 - 0.0035 17.2 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KEZ42243.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.4 1 1 0 1 1 1 0 UEV domain BRE PF06113.7 KEZ42243.1 - 0.11 11.5 0.2 0.2 10.6 0.1 1.4 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Ribosomal_L31e PF01198.14 KEZ42244.1 - 1.2e-37 127.4 0.7 1.4e-37 127.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e RGS PF00615.14 KEZ42245.1 - 4.6e-11 42.8 0.0 5.1e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain ProSAAS PF07259.7 KEZ42245.1 - 0.01 15.3 0.2 0.017 14.6 0.1 1.3 1 0 0 1 1 1 0 ProSAAS precursor PCI PF01399.22 KEZ42246.1 - 1.5e-09 38.1 0.0 3.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain LPP PF04728.8 KEZ42246.1 - 0.048 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper FlxA PF14282.1 KEZ42246.1 - 0.061 13.2 0.6 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 FlxA-like protein E1-E2_ATPase PF00122.15 KEZ42247.1 - 2.2e-54 183.9 0.5 3.8e-54 183.1 0.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ42247.1 - 4e-49 167.9 1.0 9.6e-49 166.6 0.7 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEZ42247.1 - 1.9e-42 143.1 1.0 1.6e-10 40.9 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KEZ42247.1 - 2.6e-15 57.0 0.0 5.9e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ42247.1 - 3.1e-05 23.6 0.6 0.00018 21.2 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peroxidase_2 PF01328.12 KEZ42247.1 - 0.012 14.2 0.0 0.83 8.2 0.0 2.4 2 0 0 2 2 2 0 Peroxidase, family 2 DUF155 PF02582.9 KEZ42248.1 - 7.3e-58 195.3 0.0 1.3e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 BCL_N PF04714.8 KEZ42248.1 - 0.045 13.3 0.3 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 BCL7, N-terminal conserver region LBP_BPI_CETP_C PF02886.12 KEZ42248.1 - 0.11 11.6 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain Transferase PF02458.10 KEZ42248.1 - 0.14 10.5 0.0 0.25 9.7 0.0 1.3 1 0 0 1 1 1 0 Transferase family PAT1 PF09770.4 KEZ42248.1 - 8.4 4.4 8.1 11 4.0 5.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.19 KEZ42249.1 - 3.3e-40 138.0 14.7 4.8e-40 137.4 10.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42249.1 - 1.4e-35 122.7 25.7 2e-27 95.8 6.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1145 PF06611.7 KEZ42249.1 - 8 6.1 7.7 0.96 9.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1145) DUF1510 PF07423.6 KEZ42251.1 - 0.079 12.3 13.9 3.1 7.1 7.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 KEZ42251.1 - 0.095 11.9 16.6 0.13 11.4 11.5 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 KEZ42251.1 - 0.25 9.6 14.7 0.32 9.3 10.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.8 KEZ42251.1 - 0.6 8.2 11.8 0.79 7.8 8.1 1.1 1 0 0 1 1 1 0 Utp14 protein DUF1295 PF06966.7 KEZ42253.1 - 7e-58 195.6 0.1 9.1e-58 195.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 KEZ42253.1 - 0.00045 20.3 1.2 0.001 19.2 0.0 2.2 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 KEZ42253.1 - 0.00047 19.9 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KEZ42253.1 - 0.004 17.2 0.1 0.004 17.2 0.0 2.9 4 0 0 4 4 4 1 Phospholipid methyltransferase Med8 PF10232.4 KEZ42255.1 - 9.5e-22 77.6 9.2 3.4e-21 75.7 6.4 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 CENP-B_dimeris PF09026.5 KEZ42255.1 - 0.72 10.1 6.4 0.74 10.0 2.9 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KEZ42255.1 - 2.7 7.4 9.1 4.6 6.7 6.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sulfatase PF00884.18 KEZ42256.1 - 1.3e-55 188.7 0.0 1.7e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KEZ42256.1 - 2e-23 81.9 1.5 2.9e-23 81.4 0.4 1.8 1 1 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KEZ42256.1 - 4.1e-10 39.5 0.1 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KEZ42256.1 - 0.003 16.9 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily Tox-HDC PF15656.1 KEZ42256.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature RasGAP_C PF03836.10 KEZ42257.1 - 5.1e-48 162.3 5.2 1.6e-47 160.7 3.6 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KEZ42257.1 - 3.5e-41 141.0 0.0 9.6e-41 139.6 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KEZ42257.1 - 1.3e-13 49.2 47.9 0.017 14.7 0.5 13.1 14 0 0 14 14 14 8 IQ calmodulin-binding motif CH PF00307.26 KEZ42257.1 - 1.2e-09 38.1 0.0 3.9e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain ABC_tran PF00005.22 KEZ42258.1 - 3.7e-38 130.9 0.0 2.6e-29 102.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ42258.1 - 7.9e-24 84.5 29.0 1.3e-15 57.5 7.9 3.8 3 1 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KEZ42258.1 - 1.8e-10 40.4 0.0 5e-05 22.6 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ42258.1 - 0.0021 18.0 4.6 0.44 10.4 0.1 4.2 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KEZ42258.1 - 0.012 15.4 0.0 2.8 7.9 0.0 3.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FAM176 PF14851.1 KEZ42258.1 - 0.071 12.7 4.2 0.19 11.3 0.3 3.1 3 0 0 3 3 3 0 FAM176 family Ycf1 PF05758.7 KEZ42258.1 - 0.22 9.2 0.4 0.32 8.6 0.3 1.1 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 KEZ42258.1 - 9.4 5.3 8.7 19 4.3 6.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain WD40 PF00400.27 KEZ42259.1 - 3.3e-21 74.2 9.2 0.00017 21.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KEZ42259.1 - 0.025 14.2 0.1 0.4 10.3 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KEZ42259.1 - 0.07 12.8 2.8 16 5.3 0.1 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NAD_binding_1 PF00175.16 KEZ42260.1 - 8.1e-30 103.6 0.0 1.4e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEZ42260.1 - 1.5e-22 79.5 0.0 7.9e-22 77.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEZ42260.1 - 1e-08 35.2 0.0 0.00041 20.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KEZ42260.1 - 8.3e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Ssu72 PF04722.8 KEZ42261.1 - 3.9e-85 284.1 0.0 4.5e-85 283.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.6 KEZ42262.1 - 9.8e-21 72.8 6.1 2.3e-12 46.0 0.9 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT IncA PF04156.9 KEZ42262.1 - 0.0036 16.9 35.2 0.0048 16.5 7.5 2.4 2 0 0 2 2 2 2 IncA protein AAA_13 PF13166.1 KEZ42262.1 - 0.18 10.2 18.4 0.35 9.2 12.8 1.4 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 KEZ42262.1 - 9.5 6.0 23.0 1.5 8.6 5.8 3.5 3 0 0 3 3 3 0 Prefoldin subunit Peptidase_M28 PF04389.12 KEZ42263.1 - 1.4e-16 60.7 0.0 2.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KEZ42263.1 - 3.3e-15 55.7 0.0 6.6e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KEZ42263.1 - 3.2e-05 23.5 0.2 0.00018 21.1 0.0 2.1 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 KEZ42263.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Fructosamin_kin PF03881.9 KEZ42264.1 - 2.9e-35 121.6 0.0 3.6e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEZ42264.1 - 1.4e-07 31.5 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.27 KEZ42265.1 - 1.1e-05 25.1 3.5 0.4 10.6 0.0 4.6 3 1 0 3 3 3 2 WD domain, G-beta repeat NACHT PF05729.7 KEZ42265.1 - 0.00047 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ42265.1 - 0.021 14.9 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KEZ42265.1 - 0.07 13.1 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Type_III_YscX PF09474.5 KEZ42265.1 - 0.14 12.2 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Fungal_trans PF04082.13 KEZ42267.1 - 0.0029 16.5 0.0 0.0055 15.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fibrillarin_2 PF10113.4 KEZ42267.1 - 0.18 10.0 0.0 0.26 9.5 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein MFS_1 PF07690.11 KEZ42268.1 - 3e-22 78.8 37.4 4.4e-19 68.4 15.1 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily FPN1 PF06963.7 KEZ42268.1 - 0.0053 15.1 2.0 0.012 14.0 0.1 1.9 2 0 0 2 2 2 1 Ferroportin1 (FPN1) A_deaminase PF00962.17 KEZ42269.1 - 5.2e-37 127.4 0.0 1.2e-36 126.2 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase Transp_cyt_pur PF02133.10 KEZ42271.1 - 1.4e-95 320.4 43.4 1.6e-95 320.2 30.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 KEZ42272.1 - 1.2e-24 87.0 0.1 2.1e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEZ42272.1 - 1.1e-23 83.3 0.0 2.7e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KEZ42273.1 - 2.8e-53 181.0 0.0 1.8e-21 76.1 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 Zn_clus PF00172.13 KEZ42274.1 - 0.0044 16.8 3.3 0.0081 16.0 2.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ42275.1 - 4.8e-17 61.6 0.9 7.1e-17 61.1 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ42275.1 - 0.0011 18.8 7.4 0.0021 17.9 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 KEZ42276.1 - 9.5e-21 74.1 0.4 3.2e-19 69.1 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEZ42276.1 - 1.8e-08 34.1 0.1 5.8e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEZ42276.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF1989 PF09347.5 KEZ42277.1 - 1.9e-50 170.5 0.0 2.9e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.16 KEZ42277.1 - 3.3e-19 68.7 0.0 5.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KEZ42277.1 - 0.00058 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 KEZ42277.1 - 0.12 10.4 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Glyco_hydro_57 PF03065.10 KEZ42277.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 FAD_binding_3 PF01494.14 KEZ42278.1 - 5.8e-63 213.0 0.0 7.1e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KEZ42278.1 - 3.6e-05 22.5 0.0 5.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KEZ42278.1 - 3.9e-05 23.6 0.3 0.00097 19.0 0.1 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ42278.1 - 6.7e-05 22.1 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KEZ42278.1 - 7e-05 21.8 0.1 0.00017 20.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ42278.1 - 0.00042 19.2 0.0 0.0022 16.9 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ42278.1 - 0.0008 19.3 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Phe_hydrox_dim PF07976.7 KEZ42278.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Lycopene_cycl PF05834.7 KEZ42278.1 - 0.0023 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KEZ42278.1 - 0.003 17.9 0.1 0.0064 16.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ42278.1 - 0.0084 14.6 0.0 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 KEZ42278.1 - 0.022 14.7 0.0 0.054 13.5 0.0 1.6 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ42278.1 - 0.042 12.9 0.1 0.1 11.6 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KEZ42278.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KEZ42278.1 - 0.18 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding MFS_1 PF07690.11 KEZ42279.1 - 1.4e-34 119.3 39.2 1.7e-34 119.1 25.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma70_r4 PF04545.11 KEZ42279.1 - 0.15 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4360 PF14273.1 KEZ42281.1 - 1.8e-53 180.8 0.9 2.1e-53 180.7 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) p450 PF00067.17 KEZ42282.1 - 3.9e-49 167.4 0.0 1.2e-46 159.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 HicB PF05534.7 KEZ42282.1 - 0.053 13.1 0.1 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 HicB family MOR2-PAG1_C PF14225.1 KEZ42282.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Cell morphogenesis C-terminal HET PF06985.6 KEZ42283.1 - 5.5e-29 101.0 0.1 6.6e-22 78.1 0.2 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Tannase PF07519.6 KEZ42284.1 - 1.2e-81 274.8 0.5 1.9e-81 274.1 0.4 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase HET PF06985.6 KEZ42284.1 - 6.6e-29 100.8 0.4 1.2e-28 100.0 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FPN1 PF06963.7 KEZ42284.1 - 1.2e-27 96.4 3.5 1.6e-27 95.9 2.4 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Abhydrolase_6 PF12697.2 KEZ42284.1 - 0.00021 21.2 0.1 0.0009 19.1 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ42284.1 - 0.012 14.8 0.2 0.67 9.1 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_2 PF00891.13 KEZ42287.1 - 1.4e-29 103.0 0.0 2.2e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase VWA_3 PF13768.1 KEZ42289.1 - 4.9e-30 104.2 0.0 8.8e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KEZ42289.1 - 9.8e-17 60.7 0.0 2.7e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 KEZ42289.1 - 1.4e-10 41.5 0.0 2.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEZ42289.1 - 2.2e-10 40.5 0.0 4.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KEZ42289.1 - 1.5e-05 24.3 0.0 3.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 KEZ42289.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus Choline_kinase PF01633.15 KEZ42289.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cys_Met_Meta_PP PF01053.15 KEZ42290.1 - 3.3e-23 81.6 0.0 4.4e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KEZ42290.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ImcF-related_N PF14331.1 KEZ42290.1 - 0.013 14.4 0.0 0.028 13.3 0.0 1.5 2 0 0 2 2 2 0 ImcF-related N-terminal domain Beta_elim_lyase PF01212.16 KEZ42290.1 - 0.12 11.4 0.0 0.36 9.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.11 KEZ42291.1 - 8.4e-07 28.0 12.8 2.5e-06 26.4 8.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ42291.1 - 7.2e-05 21.5 1.4 0.00011 20.9 1.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KEZ42291.1 - 0.061 11.7 3.1 0.076 11.4 2.1 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein Lipase_3 PF01764.20 KEZ42292.1 - 9.1e-18 64.2 0.1 2.7e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) MMR_HSR1 PF01926.18 KEZ42292.1 - 8.3e-05 22.5 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KEZ42292.1 - 0.0023 17.1 0.0 0.0055 15.9 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Thioesterase PF00975.15 KEZ42292.1 - 0.0027 17.9 0.3 0.015 15.5 0.0 2.4 3 0 0 3 3 3 1 Thioesterase domain SRPRB PF09439.5 KEZ42292.1 - 0.0029 16.8 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Abhydrolase_5 PF12695.2 KEZ42292.1 - 0.0097 15.6 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ42292.1 - 0.024 14.5 0.4 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.3 KEZ42292.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Dynamin_N PF00350.18 KEZ42292.1 - 0.15 11.8 0.0 0.53 10.0 0.0 1.9 1 1 0 1 1 1 0 Dynamin family Miro PF08477.8 KEZ42292.1 - 0.17 12.3 0.0 3.2 8.2 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein Alpha-L-AF_C PF06964.7 KEZ42293.1 - 5.2e-32 111.0 0.0 1e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 KEZ42294.1 - 2.5e-95 319.6 16.2 2.9e-95 319.5 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42294.1 - 1.5e-27 96.2 30.5 8.3e-20 70.7 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ42294.1 - 0.0019 17.9 0.0 0.36 10.6 0.0 2.9 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.11 KEZ42295.1 - 1e-39 136.2 25.4 2e-24 85.9 6.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily IMPDH PF00478.20 KEZ42296.1 - 2.2e-131 437.9 3.6 2.6e-131 437.7 2.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KEZ42296.1 - 4.5e-15 55.1 0.0 2.7e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 KEZ42296.1 - 1.7e-09 36.9 0.7 1.8e-08 33.6 0.4 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 KEZ42296.1 - 3.4e-07 29.7 8.2 0.011 14.9 0.0 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 KEZ42296.1 - 0.00021 20.6 4.6 0.034 13.4 0.3 2.7 2 1 1 3 3 3 2 Histidine biosynthesis protein QRPTase_C PF01729.14 KEZ42296.1 - 0.058 12.9 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.9 KEZ42296.1 - 0.072 12.1 2.4 0.35 9.8 0.5 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_hydro_31 PF01055.21 KEZ42297.1 - 5e-161 536.4 0.7 6.4e-161 536.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4448 PF14610.1 KEZ42298.1 - 3.4e-36 124.5 0.4 4.9e-36 123.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Metallophos PF00149.23 KEZ42299.1 - 1.1e-15 57.5 0.3 2e-15 56.7 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M1 PF01433.15 KEZ42300.1 - 0.00015 20.9 0.0 2.3 7.2 0.0 3.3 3 0 0 3 3 3 3 Peptidase family M1 SAS4 PF15460.1 KEZ42301.1 - 6.6e-34 115.8 0.1 3.5e-33 113.4 0.1 2.3 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 MreB_Mbl PF06723.8 KEZ42302.1 - 0.011 14.3 0.1 0.08 11.5 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein HATPase_c_2 PF13581.1 KEZ42302.1 - 0.091 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Patatin PF01734.17 KEZ42303.1 - 4.4e-30 105.1 0.0 7.3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Mito_carr PF00153.22 KEZ42304.1 - 1.4e-45 152.8 6.6 2.7e-17 62.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Polysacc_synt_4 PF04669.8 KEZ42306.1 - 1.1e-24 86.9 1.0 5.4e-24 84.6 0.7 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF3506 PF12014.3 KEZ42307.1 - 8.2e-46 155.1 0.0 3.6e-45 153.0 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KEZ42307.1 - 6.5e-06 25.7 0.1 1.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ42307.1 - 0.0031 17.1 0.1 0.0073 15.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF1769 PF08588.5 KEZ42308.1 - 2.1e-28 98.0 0.2 4e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF3591 PF12157.3 KEZ42309.1 - 1.5e-172 574.1 0.0 1.9e-172 573.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KEZ42309.1 - 0.003 17.2 0.8 0.0066 16.0 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KEZ42309.1 - 0.015 15.2 0.9 0.025 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle D-ser_dehydrat PF14031.1 KEZ42310.1 - 1.2e-23 83.1 0.0 3.4e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KEZ42310.1 - 9.9e-10 38.3 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fasciclin PF02469.17 KEZ42310.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Fasciclin domain FAD_binding_2 PF00890.19 KEZ42311.1 - 4.3e-85 286.0 0.4 5.3e-85 285.7 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KEZ42311.1 - 1.8e-22 78.9 0.3 1.5e-20 72.7 0.0 3.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KEZ42311.1 - 5e-12 45.3 2.4 2.8e-11 42.9 1.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEZ42311.1 - 2.1e-10 40.3 0.5 8e-10 38.3 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ42311.1 - 1.1e-08 34.9 0.5 1.1e-07 31.7 0.2 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEZ42311.1 - 4.7e-08 33.1 0.0 5e-06 26.5 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ42311.1 - 1.6e-06 26.8 1.9 0.0041 15.6 0.1 3.3 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 KEZ42311.1 - 4e-05 22.8 1.5 0.0062 15.6 0.4 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KEZ42311.1 - 0.0017 17.3 3.0 0.21 10.4 0.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 KEZ42311.1 - 0.0021 17.1 0.1 1.4 7.8 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KEZ42311.1 - 0.0022 18.0 0.9 0.019 15.0 0.6 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ42311.1 - 0.0042 16.8 0.5 0.036 13.8 0.2 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KEZ42311.1 - 0.0063 15.6 2.5 0.016 14.2 1.7 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEZ42311.1 - 0.16 12.3 2.7 2.8 8.4 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 KEZ42312.1 - 2.4e-123 412.0 16.7 2.7e-123 411.8 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ42312.1 - 6.4e-22 77.7 47.9 3e-20 72.2 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1689 PF07954.6 KEZ42312.1 - 0.19 11.5 0.1 2.4 8.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1689) MFS_1 PF07690.11 KEZ42314.1 - 1.8e-41 142.0 48.2 1.3e-39 135.9 32.6 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ42314.1 - 2e-09 36.2 15.8 2.8e-09 35.7 10.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ribophorin_II PF05817.9 KEZ42315.1 - 5.4e-25 87.6 0.1 7.7e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2306 PF10067.4 KEZ42315.1 - 0.62 10.2 4.6 1.2 9.3 3.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Peptidase_M28 PF04389.12 KEZ42316.1 - 1.7e-32 112.6 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.16 KEZ42317.1 - 7e-17 61.5 7.1 7e-17 61.5 4.9 2.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase UPF0242 PF06785.6 KEZ42317.1 - 0.081 11.5 1.2 0.15 10.6 0.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) Maf PF02545.9 KEZ42318.1 - 1.8e-44 151.2 0.0 2.3e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 KEZ42319.1 - 4.2e-07 29.5 0.0 6.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Amidohydro_1 PF01979.15 KEZ42320.1 - 6.8e-63 213.3 1.6 1e-62 212.7 1.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KEZ42320.1 - 5.1e-53 178.3 1.5 5.1e-53 178.3 1.0 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KEZ42320.1 - 4.5e-42 141.9 0.7 1e-41 140.8 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 KEZ42320.1 - 7.7e-39 131.7 0.0 1.7e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KEZ42320.1 - 3.7e-07 29.8 2.9 1.9e-06 27.5 2.0 2.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEZ42320.1 - 0.00021 20.6 0.0 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Ada3 PF10198.4 KEZ42321.1 - 2.1e-45 153.6 0.0 2.1e-45 153.6 0.0 2.6 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 PepSY_TM_2 PF13703.1 KEZ42322.1 - 0.061 13.5 0.4 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix HMG_box PF00505.14 KEZ42323.1 - 8.6e-07 29.1 0.1 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEZ42323.1 - 0.00023 21.4 1.1 0.00038 20.7 0.0 1.9 2 0 0 2 2 2 1 HMG-box domain TruB_N PF01509.13 KEZ42323.1 - 0.044 13.9 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Het-C PF07217.6 KEZ42324.1 - 1.5e-256 852.3 0.0 1.5e-256 852.3 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.13 KEZ42324.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C RR_TM4-6 PF06459.7 KEZ42324.1 - 2.4 8.0 33.8 5.5 6.8 23.4 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_45 PF02015.11 KEZ42325.1 - 1.4e-89 299.5 18.1 1.6e-89 299.2 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF3419 PF11899.3 KEZ42326.1 - 3.1e-148 493.5 0.0 4.4e-148 493.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KEZ42326.1 - 1.7e-12 47.3 0.0 2.2e-11 43.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42326.1 - 1.1e-08 35.6 0.0 7.7e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42326.1 - 1.7e-08 34.1 0.0 6.3e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ42326.1 - 4.9e-07 29.8 0.0 0.00016 21.7 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ42326.1 - 8.7e-07 28.2 0.0 0.0022 17.1 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KEZ42326.1 - 9.8e-07 29.1 0.0 2.8e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42326.1 - 1.9e-05 25.0 0.0 0.0054 17.1 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 KEZ42326.1 - 0.00011 21.7 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KEZ42326.1 - 0.0023 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 KEZ42326.1 - 0.21 10.9 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Utp11 PF03998.8 KEZ42328.1 - 1e-48 166.3 22.3 8.2e-48 163.3 15.4 1.9 1 1 0 1 1 1 1 Utp11 protein EMP24_GP25L PF01105.19 KEZ42328.1 - 0.98 9.1 4.0 0.65 9.6 1.5 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DAO PF01266.19 KEZ42329.1 - 1.6e-15 56.9 0.1 2.7e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase APH PF01636.18 KEZ42329.1 - 8.4e-12 45.3 0.1 5.2e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ42329.1 - 0.07 12.4 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Cmc1 PF08583.5 KEZ42330.1 - 7.2e-18 64.1 1.4 7.2e-18 64.1 1.0 1.9 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KEZ42330.1 - 0.018 14.9 0.8 0.16 11.9 0.6 2.2 1 1 0 1 1 1 0 CHCH domain fn3 PF00041.16 KEZ42331.1 - 7e-09 35.6 0.1 2e-08 34.2 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain MNHE PF01899.11 KEZ42331.1 - 0.59 9.7 2.4 0.96 9.0 1.7 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Histidinol_dh PF00815.15 KEZ42332.1 - 1.4e-180 600.3 5.2 1.9e-180 599.9 3.6 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KEZ42332.1 - 1.8e-22 78.7 0.0 3.2e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KEZ42332.1 - 9.7e-11 41.8 2.2 1.5e-10 41.2 0.1 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Peptidase_M16 PF00675.15 KEZ42333.1 - 1.4e-55 187.1 0.4 4.7e-55 185.4 0.2 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEZ42333.1 - 2.9e-41 141.1 0.1 3.3e-40 137.7 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Raffinose_syn PF05691.7 KEZ42334.1 - 6.1e-52 176.1 0.7 9.1e-42 142.5 0.0 3.0 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Spore_coat_CotO PF14153.1 KEZ42334.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Bromodomain PF00439.20 KEZ42335.1 - 8.7e-31 105.6 0.1 8.1e-14 51.3 0.1 3.1 3 0 0 3 3 3 2 Bromodomain Nop14 PF04147.7 KEZ42335.1 - 0.021 12.7 17.5 0.03 12.2 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3313 PF11769.3 KEZ42335.1 - 0.034 13.5 0.5 7.9 5.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3313) Spore_coat_CotO PF14153.1 KEZ42335.1 - 0.3 10.4 7.9 0.75 9.2 5.4 1.6 1 0 0 1 1 1 0 Spore coat protein CotO PPP4R2 PF09184.6 KEZ42335.1 - 0.53 9.7 21.0 0.91 9.0 14.5 1.3 1 0 0 1 1 1 0 PPP4R2 Daxx PF03344.10 KEZ42335.1 - 2.4 6.5 21.7 4.7 5.5 15.0 1.4 1 0 0 1 1 1 0 Daxx Family CKS PF01111.14 KEZ42336.1 - 3.6e-36 122.8 0.8 4.8e-36 122.4 0.5 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.10 KEZ42337.1 - 2.8e-139 464.1 0.0 3.5e-139 463.7 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ACT_3 PF10000.4 KEZ42337.1 - 0.035 13.8 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 ACT domain HVSL PF09749.4 KEZ42338.1 - 2.2e-64 216.7 0.0 2.8e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 KEZ42339.1 - 5.4e-07 30.1 0.1 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein CPSF_A PF03178.10 KEZ42340.1 - 1.2e-76 257.9 0.0 4.7e-76 255.9 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region zf-HIT PF04438.11 KEZ42342.1 - 0.032 13.8 0.7 0.048 13.3 0.5 1.2 1 0 0 1 1 1 0 HIT zinc finger zf-B_box PF00643.19 KEZ42342.1 - 0.16 11.8 3.3 2.3 8.2 2.3 2.1 1 1 0 1 1 1 0 B-box zinc finger zf-C3HC4_2 PF13923.1 KEZ42342.1 - 0.52 10.3 4.5 0.86 9.6 3.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Opy2 PF09463.5 KEZ42342.1 - 0.74 9.9 8.3 1.3 9.1 5.8 1.4 1 0 0 1 1 1 0 Opy2 protein Thg1C PF14413.1 KEZ42343.1 - 2e-15 56.5 4.5 3.6e-08 33.1 0.3 2.2 1 1 0 2 2 2 2 Thg1 C terminal domain Thg1 PF04446.7 KEZ42343.1 - 0.00015 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 KEZ42344.1 - 0.00023 20.9 1.1 0.87 9.5 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KEZ42344.1 - 0.093 12.1 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain RNA_pol_Rpb1_1 PF04997.7 KEZ42345.1 - 1.4e-108 363.1 0.0 2e-108 362.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KEZ42345.1 - 2.6e-101 338.5 0.0 4.2e-101 337.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KEZ42345.1 - 1.5e-67 226.6 0.0 3e-67 225.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KEZ42345.1 - 5.8e-52 176.1 0.1 9.8e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KEZ42345.1 - 6.2e-42 143.0 0.0 2.1e-41 141.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KEZ42345.1 - 1.2e-40 138.3 7.0 4.3e-40 136.5 4.8 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KEZ42345.1 - 8.1e-37 125.2 0.1 1.7e-36 124.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KEZ42345.1 - 3e-05 23.7 167.0 0.037 14.1 6.9 12.4 7 3 6 14 14 14 11 RNA polymerase Rpb1 C-terminal repeat HycH PF07450.6 KEZ42345.1 - 0.14 12.2 0.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH HSP70 PF00012.15 KEZ42346.1 - 7.7e-235 780.4 4.1 8.6e-235 780.2 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ42346.1 - 1e-14 53.9 0.1 1e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KEZ42346.1 - 0.00025 20.7 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KEZ42346.1 - 0.0037 17.1 1.4 4.3 7.2 0.4 3.9 2 1 0 2 2 2 2 Cell division protein FtsA DUF726 PF05277.7 KEZ42347.1 - 5.1e-111 370.8 0.0 6.8e-111 370.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KEZ42347.1 - 0.00054 19.9 0.4 0.0016 18.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KEZ42347.1 - 0.0031 17.7 0.0 0.0064 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KEZ42347.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 KEZ42347.1 - 0.079 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 KEZ42347.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF1708 PF08101.6 KEZ42348.1 - 2.6e-153 510.8 0.0 3.3e-153 510.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF4319 PF14203.1 KEZ42349.1 - 0.074 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4319) UDG PF03167.14 KEZ42350.1 - 3.7e-25 88.1 0.1 5.3e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mito_carr PF00153.22 KEZ42351.1 - 1.2e-62 207.6 1.2 2.7e-23 81.4 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF3446 PF11928.3 KEZ42351.1 - 0.056 13.6 0.9 0.14 12.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Fungal_trans PF04082.13 KEZ42352.1 - 3.4e-15 55.6 0.0 5.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ42352.1 - 2.5e-06 27.2 9.6 2.5e-06 27.2 6.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 KEZ42353.1 - 0.0012 18.7 0.0 0.0042 17.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function DUF59 PNP_UDP_1 PF01048.15 KEZ42354.1 - 7.4e-10 38.1 0.0 1.6e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_11 PF13414.1 KEZ42354.1 - 0.025 14.2 0.1 0.064 12.9 0.1 1.7 1 0 0 1 1 1 0 TPR repeat Mito_carr PF00153.22 KEZ42355.1 - 7.7e-42 140.9 0.1 1.7e-22 78.8 0.0 3.4 3 0 0 3 3 3 2 Mitochondrial carrier protein GTP_EFTU PF00009.22 KEZ42355.1 - 3.8e-41 140.5 0.0 5.9e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEZ42355.1 - 1.1e-23 83.0 0.0 2.2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KEZ42355.1 - 3.3e-20 71.7 0.0 8.3e-20 70.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEZ42355.1 - 1e-06 28.7 0.0 2.8e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KEZ42355.1 - 2.3e-06 27.3 0.0 4.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KEZ42355.1 - 4.5e-05 23.3 0.1 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ42355.1 - 0.0064 16.9 0.0 0.016 15.7 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KEZ42355.1 - 0.22 10.1 0.0 0.4 9.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Thiolase_N PF00108.18 KEZ42356.1 - 5.3e-95 317.3 0.2 5.3e-95 317.3 0.1 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEZ42356.1 - 6.4e-48 161.2 1.3 1e-47 160.6 0.2 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KEZ42356.1 - 4.4e-05 23.0 0.4 0.00016 21.2 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KEZ42356.1 - 0.007 16.3 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KEZ42356.1 - 2.2 8.0 5.2 9.1 6.0 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PAH PF02671.16 KEZ42357.1 - 5.7e-41 137.8 4.0 3.3e-16 58.6 0.0 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KEZ42357.1 - 7.8e-39 131.5 0.3 5.2e-38 128.8 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor IF4E PF01652.13 KEZ42358.1 - 2.6e-60 202.7 0.2 3.3e-60 202.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 KEZ42359.1 - 3.2e-75 253.1 0.0 3.7e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ42359.1 - 2.2e-12 47.7 0.1 4.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 KEZ42360.1 - 3.3e-28 97.4 1.8 5.7e-28 96.6 1.2 1.4 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.13 KEZ42361.1 - 6e-58 195.9 0.1 1.1e-57 195.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KEZ42361.1 - 1.2e-21 76.9 0.0 2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KEZ42361.1 - 2.1e-12 46.7 11.6 4.9e-12 45.5 8.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger VPS28 PF03997.7 KEZ42362.1 - 2.1e-55 187.2 0.0 2.4e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 KEZ42362.1 - 0.12 12.2 4.9 0.28 10.9 0.2 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Cep57_MT_bd PF06657.8 KEZ42363.1 - 6.2e-30 102.9 0.9 6.2e-30 102.9 0.6 5.4 6 1 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KEZ42363.1 - 2.2e-21 75.5 70.0 9.4e-15 54.3 6.1 6.5 5 2 1 6 6 6 3 Centrosome localisation domain of PPC89 Cast PF10174.4 KEZ42363.1 - 2.6e-06 25.8 46.9 0.089 10.8 33.9 4.0 2 1 1 3 3 3 2 RIM-binding protein of the cytomatrix active zone DUF904 PF06005.7 KEZ42363.1 - 0.02 15.1 65.7 0.034 14.4 4.8 8.4 4 1 3 7 7 7 0 Protein of unknown function (DUF904) IncA PF04156.9 KEZ42363.1 - 0.37 10.3 67.2 0.099 12.2 9.1 5.2 2 1 4 6 6 6 0 IncA protein Myosin_tail_1 PF01576.14 KEZ42363.1 - 0.47 8.1 63.6 0.0053 14.5 34.4 3.1 2 1 1 3 3 3 0 Myosin tail NPV_P10 PF05531.7 KEZ42363.1 - 0.5 10.6 22.1 18 5.6 0.1 7.3 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.13 KEZ42363.1 - 3.6 7.3 52.9 1 9.1 0.2 8.5 7 1 1 8 8 8 0 Homeobox associated leucine zipper CCDC155 PF14662.1 KEZ42363.1 - 4.5 6.8 68.3 0.054 13.0 12.0 5.7 4 1 2 6 6 6 0 Coiled-coil region of CCDC155 Glyco_hydro_76 PF03663.9 KEZ42364.1 - 4e-21 75.8 6.9 2.5e-16 60.0 0.4 2.6 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 MBOAT PF03062.14 KEZ42365.1 - 3.7e-48 164.2 23.8 7e-48 163.4 16.4 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_M56 PF05569.6 KEZ42366.1 - 0.63 8.9 6.4 2 7.3 0.3 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 DctQ PF04290.7 KEZ42366.1 - 1.5 8.6 19.8 0.12 12.1 3.2 2.6 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component UDPGP PF01704.13 KEZ42367.1 - 9.4e-56 189.1 0.0 1.2e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KEZ42367.1 - 0.088 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain tRNA-synt_1g PF09334.6 KEZ42368.1 - 1.6e-140 468.1 0.0 2.1e-140 467.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KEZ42368.1 - 3.4e-09 35.2 0.0 3e-05 22.2 0.0 3.7 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEZ42368.1 - 0.0049 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA MbeD_MobD PF04899.7 KEZ42369.1 - 0.033 14.0 2.2 5.8 6.8 0.1 2.8 2 0 0 2 2 2 0 MbeD/MobD like Synaptobrevin PF00957.16 KEZ42369.1 - 0.22 11.1 2.2 0.86 9.2 0.1 2.5 3 0 0 3 3 3 0 Synaptobrevin Cast PF10174.4 KEZ42369.1 - 0.66 7.9 4.4 1.4 6.8 0.4 2.1 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone F-box-like PF12937.2 KEZ42370.1 - 1.3e-14 53.6 0.4 2.6e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ42370.1 - 2e-05 24.0 0.6 2e-05 24.0 0.4 2.4 3 0 0 3 3 3 1 F-box domain Chromate_transp PF02417.10 KEZ42371.1 - 4.6e-47 159.7 33.9 5e-28 97.8 10.4 2.6 3 0 0 3 3 3 2 Chromate transporter Thioredoxin_4 PF13462.1 KEZ42373.1 - 4.3e-09 36.5 0.0 5.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KEZ42373.1 - 0.021 14.3 0.9 0.74 9.3 0.1 2.5 2 1 0 2 2 2 0 DSBA-like thioredoxin domain 2OG-FeII_Oxy PF03171.15 KEZ42374.1 - 0.088 13.1 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 KEZ42375.1 - 1.3e-53 181.2 0.2 1.3e-53 181.2 0.1 1.4 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 KEZ42375.1 - 0.00094 19.2 0.0 0.0034 17.4 0.0 2.1 1 1 0 1 1 1 1 Fascin domain Frataxin_Cyay PF01491.11 KEZ42375.1 - 0.0059 16.3 0.0 0.12 12.1 0.0 2.5 3 0 0 3 3 3 1 Frataxin-like domain Calmodulin_bind PF07887.6 KEZ42375.1 - 0.15 11.0 2.5 0.23 10.4 1.7 1.2 1 0 0 1 1 1 0 Calmodulin binding protein-like WD40 PF00400.27 KEZ42376.1 - 8.1e-13 47.7 0.3 0.0044 16.8 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Sel1 PF08238.7 KEZ42377.1 - 1.3e-44 149.6 39.6 5.9e-06 26.7 0.0 13.7 13 0 0 13 13 13 10 Sel1 repeat TPR_11 PF13414.1 KEZ42377.1 - 1.4e-05 24.6 13.3 0.0001 21.8 0.2 5.0 4 1 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 KEZ42377.1 - 0.02 15.5 26.6 8.9 7.1 0.0 8.0 5 2 3 8 8 8 0 Tetratricopeptide repeat DUF4398 PF14346.1 KEZ42377.1 - 0.059 13.4 0.3 38 4.4 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4398) SNAP PF14938.1 KEZ42377.1 - 0.44 9.6 4.8 0.38 9.8 0.1 3.1 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_1 PF00515.23 KEZ42377.1 - 0.81 9.4 16.5 0.98 9.1 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PX PF00787.19 KEZ42378.1 - 7.5e-23 80.4 0.0 1e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 PX domain CybS PF05328.7 KEZ42379.1 - 1.3e-47 160.7 0.0 1.7e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 CybS tRNA-synt_1b PF00579.20 KEZ42380.1 - 1.1e-77 261.1 0.0 1.4e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NPR2 PF06218.6 KEZ42381.1 - 6.2e-115 384.3 0.0 5.8e-112 374.5 0.0 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 ubiquitin PF00240.18 KEZ42382.1 - 4.9e-20 70.6 0.1 8.1e-20 69.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KEZ42382.1 - 3.7e-08 32.9 0.0 6.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 KEZ42382.1 - 5.8e-06 25.9 0.1 8.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEZ42382.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KEZ42382.1 - 0.00048 19.9 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KEZ42382.1 - 0.064 13.5 0.6 0.22 11.8 0.4 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain IBN_N PF03810.14 KEZ42383.1 - 8.9e-08 31.9 0.0 4.1e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KEZ42383.1 - 0.0015 18.4 0.1 0.067 13.1 0.0 3.5 3 0 0 3 3 3 1 Exportin 1-like protein CAS_CSE1 PF03378.10 KEZ42383.1 - 0.022 13.0 0.1 3.7 5.7 0.0 3.2 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus MFS_1_like PF12832.2 KEZ42384.1 - 6.7e-18 64.2 0.1 6.7e-18 64.2 0.0 3.2 3 0 0 3 3 3 1 MFS_1 like family L27_2 PF09045.5 KEZ42384.1 - 0.15 11.5 0.1 0.6 9.7 0.0 1.9 1 1 1 2 2 2 0 L27_2 Pribosyltran PF00156.22 KEZ42385.1 - 2.9e-15 56.0 0.0 4.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEZ42385.1 - 0.0024 17.1 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 KEZ42386.1 - 5.9e-128 427.3 0.0 7.3e-128 427.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase_C PF00433.19 KEZ42386.1 - 0.0099 16.3 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain DUF1996 PF09362.5 KEZ42387.1 - 8.7e-87 290.6 0.9 1.1e-86 290.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) UPF0052 PF01933.13 KEZ42388.1 - 1.7e-50 172.0 0.0 2.6e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 GFO_IDH_MocA PF01408.17 KEZ42388.1 - 5.4e-20 72.1 0.0 1e-19 71.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KEZ42388.1 - 3.5e-05 23.5 0.0 0.00015 21.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KEZ42388.1 - 8.9e-05 22.8 0.0 0.00036 20.9 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain RGS PF00615.14 KEZ42390.1 - 1.5e-05 25.0 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain p450 PF00067.17 KEZ42391.1 - 4.7e-16 58.3 0.0 1.3e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF1517 PF07466.6 KEZ42392.1 - 0.011 14.8 0.7 0.021 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF912 PF06024.7 KEZ42392.1 - 0.14 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S41 PF03572.13 KEZ42393.1 - 3.6e-06 26.4 0.0 7.2e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 FAA_hydrolase PF01557.13 KEZ42394.1 - 2.3e-56 190.6 0.0 3.3e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GMC_oxred_N PF00732.14 KEZ42395.1 - 3e-48 164.4 0.0 8.3e-48 163.0 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ42395.1 - 1.7e-32 112.7 0.0 3.2e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ42395.1 - 4.2e-06 25.8 0.4 0.023 13.6 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ42395.1 - 6.7e-06 25.2 0.1 0.07 11.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KEZ42395.1 - 0.0011 19.1 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ42395.1 - 0.0031 17.4 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ42395.1 - 0.0075 16.2 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEZ42395.1 - 0.17 10.2 0.0 11 4.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_61 PF03443.9 KEZ42398.1 - 1.6e-59 201.3 0.1 1.9e-59 201.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAPRTase PF04095.11 KEZ42399.1 - 3.3e-54 183.7 0.0 4.5e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 KEZ42400.1 - 1.1e-09 37.7 18.9 0.019 14.8 0.0 8.0 9 0 0 9 9 9 6 WD domain, G-beta repeat Rad4 PF03835.10 KEZ42401.1 - 4.5e-15 55.3 4.2 8.2e-15 54.4 2.9 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KEZ42401.1 - 1.5e-10 41.2 2.5 3.3e-10 40.1 1.7 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Mating_C PF12737.2 KEZ42402.1 - 0.014 14.2 9.9 0.016 14.1 6.9 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Memo PF01875.12 KEZ42403.1 - 2.1e-73 246.6 0.0 2.4e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein SNARE PF05739.14 KEZ42404.1 - 9.8e-14 50.7 7.7 9.8e-14 50.7 5.3 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KEZ42404.1 - 1.4e-07 31.6 0.5 1.4e-07 31.6 0.3 2.8 2 1 0 2 2 2 1 Syntaxin Rifin_STEVOR PF02009.11 KEZ42404.1 - 0.00031 20.4 2.7 0.00031 20.4 1.9 1.7 2 0 0 2 2 2 1 Rifin/stevor family DUF805 PF05656.9 KEZ42404.1 - 0.027 14.3 0.1 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) ACC_epsilon PF13822.1 KEZ42404.1 - 0.045 14.1 0.1 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit MARVEL PF01284.18 KEZ42404.1 - 0.059 13.1 0.1 0.087 12.6 0.1 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF1993 PF09351.5 KEZ42404.1 - 1.1 9.1 5.1 0.96 9.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Synaptobrevin PF00957.16 KEZ42404.1 - 4.8 6.8 11.4 24 4.6 7.9 2.2 1 1 0 1 1 1 0 Synaptobrevin Rhodanese PF00581.15 KEZ42405.1 - 7.9e-23 80.9 0.0 2.8e-12 46.9 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain Ribosomal_S5 PF00333.15 KEZ42406.1 - 2.1e-28 97.8 2.1 2.1e-28 97.8 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KEZ42406.1 - 1e-21 75.9 0.0 2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 KEZ42406.1 - 2 8.8 16.0 0.12 12.8 7.5 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 CENP-B_dimeris PF09026.5 KEZ42408.1 - 1.9 8.7 10.7 0.39 10.9 3.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.7 KEZ42408.1 - 2.8 7.1 5.8 6 6.0 4.0 1.5 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KEZ42408.1 - 8.8 5.8 13.7 29 4.1 7.3 2.4 2 0 0 2 2 2 0 Nucleoplasmin Cyclin_N PF00134.18 KEZ42409.1 - 4e-38 129.8 0.1 8.4e-38 128.8 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KEZ42409.1 - 2.8e-11 43.3 0.1 5.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4511 PF14974.1 KEZ42409.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) DUF1713 PF08213.6 KEZ42410.1 - 1.6e-05 24.4 24.0 1.6e-05 24.4 16.6 2.5 3 0 0 3 3 3 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 KEZ42410.1 - 0.007 16.3 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial protein Pet20 SOG2 PF10428.4 KEZ42410.1 - 0.017 13.7 4.9 0.019 13.6 3.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAD_binding_8 PF08022.7 KEZ42411.1 - 5.4e-23 80.8 0.0 1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KEZ42411.1 - 2.8e-22 79.3 0.0 4.4e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KEZ42411.1 - 3.9e-18 65.7 9.0 8.4e-18 64.6 6.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KEZ42411.1 - 5.8e-05 23.1 0.0 0.00017 21.6 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEZ42411.1 - 0.11 13.0 0.0 2.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain GNAT_acetyltr_2 PF13718.1 KEZ42412.1 - 3.3e-80 268.0 0.0 6.2e-80 267.1 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KEZ42412.1 - 5.1e-66 221.6 0.0 1.5e-65 220.0 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KEZ42412.1 - 2e-40 136.3 0.1 4.9e-40 135.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KEZ42412.1 - 5.2e-31 106.7 0.6 1.5e-30 105.2 0.4 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_30 PF13604.1 KEZ42412.1 - 4.8e-05 23.0 0.1 0.076 12.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain Acetyltransf_7 PF13508.1 KEZ42412.1 - 0.11 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Myosin_head PF00063.16 KEZ42413.1 - 5.7e-232 771.6 1.6 1.2e-231 770.5 1.1 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KEZ42413.1 - 2.6e-36 124.8 0.0 7.9e-36 123.2 0.0 1.9 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 KEZ42413.1 - 2e-13 49.5 0.2 4.5e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ42413.1 - 2e-11 43.2 0.2 1.3e-10 40.6 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 KEZ42413.1 - 8.1e-10 38.0 0.0 1.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KEZ42413.1 - 0.0013 18.1 9.7 0.04 13.5 1.7 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KEZ42413.1 - 0.0057 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF552 PF04472.7 KEZ42413.1 - 0.015 15.2 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Hpr_kinase_C PF07475.7 KEZ42413.1 - 0.017 14.4 0.3 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 KEZ42413.1 - 0.019 14.0 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 KEZ42413.1 - 0.052 14.3 0.0 0.19 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEZ42413.1 - 0.092 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEZ42413.1 - 0.11 12.1 0.1 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain SLD3 PF08639.5 KEZ42414.1 - 0.55 8.7 6.6 0.76 8.3 4.5 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 HNH_2 PF13391.1 KEZ42415.1 - 0.0012 18.6 0.4 0.0012 18.6 0.2 3.3 3 1 0 3 3 3 2 HNH endonuclease Pkinase PF00069.20 KEZ42416.1 - 4.9e-11 42.2 0.0 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42416.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase BRCT PF00533.21 KEZ42416.1 - 0.24 11.5 0.0 0.54 10.4 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AT_hook PF02178.14 KEZ42416.1 - 1.8 8.5 17.4 0.56 10.0 1.8 4.1 3 0 0 3 3 3 0 AT hook motif MpPF1 PF07668.6 KEZ42417.1 - 0.11 11.6 0.6 0.15 11.1 0.4 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 1 MgtE_N PF03448.12 KEZ42417.1 - 0.17 12.2 2.5 1.5 9.1 0.2 2.1 2 0 0 2 2 2 0 MgtE intracellular N domain DAHP_synth_2 PF01474.11 KEZ42418.1 - 1.1e-189 630.3 0.0 1.3e-189 630.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Aldose_epim PF01263.15 KEZ42419.1 - 4e-36 124.6 0.0 5e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.3 KEZ42420.1 - 1e-119 399.8 0.3 3.2e-119 398.2 0.0 1.8 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Chromo PF00385.19 KEZ42421.1 - 2.7e-17 62.1 1.9 4.8e-17 61.3 1.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PQ-loop PF04193.9 KEZ42422.1 - 6.5e-24 83.2 2.2 8.1e-14 50.9 0.4 2.5 2 0 0 2 2 2 2 PQ loop repeat tRNA-synt_2 PF00152.15 KEZ42423.1 - 2.4e-90 302.6 0.0 3e-90 302.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEZ42423.1 - 0.021 14.6 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ANTH PF07651.11 KEZ42424.1 - 1.3e-69 234.0 0.2 1.9e-69 233.4 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KEZ42424.1 - 2e-07 30.8 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain KAR9 PF08580.5 KEZ42424.1 - 7.1 4.7 7.8 5.9 5.0 0.7 2.6 3 0 0 3 3 3 0 Yeast cortical protein KAR9 CS PF04969.11 KEZ42425.1 - 4.1e-16 59.3 0.0 1e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 CS domain Glyco_hydro_3 PF00933.16 KEZ42426.1 - 7.1e-77 258.3 0.0 1e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ42426.1 - 1.5e-72 243.7 0.0 3.8e-71 239.2 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ42426.1 - 1.5e-22 79.3 0.0 3.2e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KEZ42426.1 - 2.3e-20 72.7 0.0 4.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Cation_efflux PF01545.16 KEZ42427.1 - 4.9e-57 193.1 0.1 1.3e-56 191.7 0.0 1.6 1 1 0 1 1 1 1 Cation efflux family MFS_1 PF07690.11 KEZ42428.1 - 2.1e-35 122.1 78.2 2.2e-31 108.8 21.5 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ42428.1 - 4.7e-15 54.8 32.8 7.9e-15 54.0 20.5 2.1 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEZ42428.1 - 3.1e-10 39.2 18.0 3.1e-10 39.2 12.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter BTP PF05232.7 KEZ42428.1 - 0.15 11.8 5.8 0.35 10.6 2.4 3.0 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family Rad1 PF02144.11 KEZ42429.1 - 3.5e-77 258.8 0.0 4e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF3096 PF11295.3 KEZ42430.1 - 0.013 14.9 1.3 0.031 13.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) FA_desaturase PF00487.19 KEZ42430.1 - 0.021 14.2 1.3 0.023 14.1 0.9 1.0 1 0 0 1 1 1 0 Fatty acid desaturase UPF0197 PF05251.7 KEZ42430.1 - 0.21 11.9 7.1 0.32 11.3 4.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Bromodomain PF00439.20 KEZ42431.1 - 2.1e-27 94.8 0.2 4.3e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KEZ42431.1 - 2.4e-09 37.1 0.6 4.3e-09 36.4 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEZ42431.1 - 5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEZ42431.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ribosomal_L18ae PF01775.12 KEZ42433.1 - 2.3e-59 198.6 0.5 3.1e-59 198.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 KEZ42434.1 - 2.3e-13 50.3 0.0 1.8e-12 47.4 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_11 PF13414.1 KEZ42434.1 - 0.035 13.7 0.1 0.12 12.0 0.1 1.9 1 0 0 1 1 1 0 TPR repeat BTB PF00651.26 KEZ42435.1 - 4.9e-08 32.9 0.0 1.5e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Fungal_trans PF04082.13 KEZ42436.1 - 5.6e-14 51.6 1.4 8.6e-14 51.0 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Homeobox_KN PF05920.6 KEZ42437.1 - 2.5e-21 75.0 0.4 6e-21 73.8 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KEZ42437.1 - 1.8e-08 33.8 1.3 4e-08 32.7 0.9 1.6 1 0 0 1 1 1 1 Homeobox domain Rhodanese PF00581.15 KEZ42438.1 - 7.4e-09 35.9 0.0 2.1e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Homeobox PF00046.24 KEZ42438.1 - 3.9e-08 32.7 0.1 1.5e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Homeobox domain Peptidase_C14 PF00656.17 KEZ42438.1 - 0.062 12.9 0.0 0.31 10.6 0.0 1.8 1 1 1 2 2 2 0 Caspase domain PIG-X PF08320.7 KEZ42439.1 - 4e-63 212.4 0.0 5.4e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 FeoB_C PF07664.7 KEZ42439.1 - 0.029 13.8 0.7 0.062 12.7 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Cas1_AcylT PF07779.7 KEZ42440.1 - 3.7e-53 180.7 6.7 3.9e-42 144.3 1.2 2.2 2 0 0 2 2 2 2 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 KEZ42440.1 - 3.3e-20 73.0 0.0 5.4e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF4149 PF13664.1 KEZ42440.1 - 0.037 14.0 0.1 0.037 14.0 0.1 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF4149) Arf PF00025.16 KEZ42442.1 - 6e-39 133.0 0.1 1.6e-24 86.0 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 KEZ42442.1 - 7.1e-12 44.7 0.0 2.8e-08 32.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KEZ42442.1 - 6e-08 32.1 0.0 6.7e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KEZ42442.1 - 8.8e-08 31.6 0.0 0.0006 19.2 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.5 KEZ42442.1 - 6.2e-07 28.8 0.0 8.1e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Miro PF08477.8 KEZ42442.1 - 1.1e-05 25.8 0.0 7.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KEZ42442.1 - 0.0004 19.8 0.0 0.0023 17.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEZ42442.1 - 0.0031 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.16 KEZ42443.1 - 2.1e-23 83.0 0.0 2.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEZ42443.1 - 2.3e-09 37.0 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 KEZ42444.1 - 3.7e-79 265.9 24.3 4.1e-79 265.7 16.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.1 KEZ42444.1 - 0.025 14.6 15.0 0.033 14.2 10.4 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Daxx PF03344.10 KEZ42444.1 - 0.14 10.6 19.6 0.14 10.5 13.6 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 KEZ42444.1 - 5.2 4.6 11.5 6.2 4.3 8.0 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 KEZ42444.1 - 6.7 5.2 9.1 8.2 4.9 6.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FGGY_C PF02782.11 KEZ42445.1 - 1.3e-26 93.4 0.0 3.9e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KEZ42445.1 - 7.4e-17 61.4 0.0 7.2e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 KEZ42446.1 - 2.5e-51 174.4 3.4 3.2e-51 174.0 2.4 1.1 1 0 0 1 1 1 1 Cation efflux family HCV_env PF01539.12 KEZ42446.1 - 0.44 9.9 4.5 0.28 10.6 1.3 1.8 1 1 1 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 MFS_1 PF07690.11 KEZ42447.1 - 2.3e-18 66.0 34.3 2.3e-18 66.0 23.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily ATG22 PF11700.3 KEZ42447.1 - 0.003 16.0 14.5 0.007 14.8 9.9 1.6 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like DoxD PF04173.8 KEZ42447.1 - 0.032 13.9 3.3 0.086 12.5 2.3 1.7 1 0 0 1 1 1 0 TQO small subunit DoxD DUF3649 PF12365.3 KEZ42447.1 - 0.089 12.3 0.4 0.089 12.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) PQ-loop PF04193.9 KEZ42448.1 - 4.1e-40 135.1 19.1 3.2e-21 74.6 1.7 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4381 PF14316.1 KEZ42448.1 - 0.39 10.8 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TIP41 PF04176.8 KEZ42449.1 - 3.1e-70 235.1 0.2 4e-70 234.7 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family ERM PF00769.14 KEZ42450.1 - 0.00013 21.6 8.1 0.00019 21.0 5.6 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Bacillus_HBL PF05791.6 KEZ42450.1 - 0.035 13.4 2.1 0.07 12.4 1.2 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 KEZ42450.1 - 0.087 12.3 12.1 0.16 11.4 7.9 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 KEZ42450.1 - 0.1 12.4 18.5 0.35 10.7 12.8 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS6_N PF14661.1 KEZ42450.1 - 0.13 11.6 9.5 0.15 11.3 5.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 KEZ42450.1 - 0.13 11.3 16.7 0.08 11.9 8.8 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-H PF05837.7 KEZ42450.1 - 0.16 12.1 11.8 0.29 11.3 7.6 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF2968 PF11180.3 KEZ42450.1 - 0.31 10.3 12.2 0.045 13.1 5.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FliJ PF02050.11 KEZ42450.1 - 0.37 10.8 17.9 0.35 10.9 11.0 1.9 2 0 0 2 2 2 0 Flagellar FliJ protein DUF607 PF04678.8 KEZ42450.1 - 0.81 9.5 5.5 1 9.2 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF607 V_ATPase_I PF01496.14 KEZ42450.1 - 1.1 7.0 3.6 1.4 6.6 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KEZ42450.1 - 1.2 7.5 6.3 1.9 6.8 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LMBR1 PF04791.11 KEZ42450.1 - 1.4 7.4 3.1 1.9 7.0 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 KEZ42450.1 - 1.8 8.1 19.3 5.5 6.5 13.4 1.9 1 1 0 1 1 1 0 IncA protein ING PF12998.2 KEZ42450.1 - 2.7 8.3 10.4 2.7 8.3 5.7 2.1 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding TMF_DNA_bd PF12329.3 KEZ42450.1 - 4.5 7.1 19.1 6.4 6.6 9.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 KEZ42450.1 - 6.3 5.6 13.9 59 2.4 10.3 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 KEZ42451.1 - 6.1e-71 238.6 0.0 7.6e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42451.1 - 3.3e-44 150.8 0.0 4.4e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42451.1 - 1.6e-07 30.5 0.0 5.1e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEZ42451.1 - 0.00044 19.3 0.1 0.00082 18.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KEZ42451.1 - 0.0035 16.7 0.0 0.046 13.0 0.0 2.2 1 1 1 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.4 KEZ42451.1 - 0.0089 15.3 0.1 0.022 14.1 0.1 1.7 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KEZ42451.1 - 0.019 14.7 0.1 0.046 13.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Agro_virD5 PF04730.7 KEZ42451.1 - 0.25 9.3 1.5 0.36 8.8 1.1 1.1 1 0 0 1 1 1 0 Agrobacterium VirD5 protein Peptidase_M76 PF09768.4 KEZ42452.1 - 7.8e-65 217.5 0.7 9.6e-65 217.2 0.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KEZ42452.1 - 0.00023 20.8 1.5 0.00023 20.8 1.0 1.8 1 1 1 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 KEZ42452.1 - 0.054 13.5 0.6 0.099 12.6 0.0 1.7 2 0 0 2 2 2 0 Peptidase MA superfamily GCC2_GCC3 PF07699.8 KEZ42452.1 - 0.065 12.8 0.7 3 7.4 0.0 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 AA_kinase PF00696.23 KEZ42453.1 - 1.1e-38 133.1 1.6 1.6e-38 132.6 1.1 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KEZ42453.1 - 2.8e-15 55.7 0.5 1.6e-14 53.3 0.1 2.4 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.8 KEZ42454.1 - 2e-09 37.3 0.0 3.7e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KEZ42454.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 PUA domain UCH PF00443.24 KEZ42456.1 - 2.2e-45 154.8 0.1 3.7e-45 154.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 KEZ42456.1 - 4e-22 78.2 0.0 7.2e-21 74.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 KEZ42456.1 - 8.6e-15 54.9 0.0 2.7e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3848 PF12959.2 KEZ42457.1 - 0.067 13.1 0.1 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) HEAT PF02985.17 KEZ42458.1 - 0.00058 19.7 0.1 0.029 14.4 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 KEZ42458.1 - 0.0027 17.9 0.2 1.2 9.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KEZ42458.1 - 0.0092 16.4 2.3 6.8 7.3 0.2 4.2 3 0 0 3 3 3 2 HEAT-like repeat DUF908 PF06012.7 KEZ42458.1 - 0.016 14.5 0.9 74 2.4 0.0 4.9 4 1 1 6 6 6 0 Domain of Unknown Function (DUF908) rRNA_processing PF08524.6 KEZ42458.1 - 0.018 14.8 7.1 0.052 13.3 5.0 1.7 1 0 0 1 1 1 0 rRNA processing DUF1749 PF08538.5 KEZ42459.1 - 2.3e-76 256.5 0.0 2.8e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KEZ42459.1 - 1.2e-11 44.8 0.0 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ42459.1 - 5.5e-08 32.6 0.0 3.7e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ42459.1 - 0.0012 18.4 0.1 0.0027 17.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KEZ42459.1 - 0.026 13.9 0.1 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_7 PF12715.2 KEZ42459.1 - 0.03 13.2 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase family LCAT PF02450.10 KEZ42459.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase p450 PF00067.17 KEZ42460.1 - 8.4e-47 159.7 0.0 1.6e-40 139.0 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 Menin PF05053.8 KEZ42461.1 - 1.8 6.6 3.2 2.6 6.1 2.2 1.1 1 0 0 1 1 1 0 Menin SelP_N PF04592.9 KEZ42461.1 - 2.4 7.4 12.2 3.9 6.7 8.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tim17 PF02466.14 KEZ42463.1 - 6.2e-25 87.7 4.4 9e-25 87.1 2.5 1.7 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family HTH_psq PF05225.11 KEZ42463.1 - 6e-07 28.9 0.0 4.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 KEZ42463.1 - 0.031 14.2 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NUDIX PF00293.23 KEZ42464.1 - 3.2e-18 65.6 0.0 6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KEZ42464.1 - 3.5e-10 40.1 0.0 1.4e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KEZ42464.1 - 1.8e-08 33.7 1.9 3.2e-08 32.9 1.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Trypan_PARP PF05887.6 KEZ42465.1 - 0.0011 18.7 0.1 0.0016 18.3 0.1 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Muted PF14942.1 KEZ42465.1 - 0.023 14.5 0.8 0.034 14.0 0.6 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Peptidase_C50 PF03568.12 KEZ42466.1 - 1.8e-112 375.8 0.0 3e-112 375.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KEZ42466.1 - 1e-08 34.9 12.8 0.012 15.5 0.3 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat CHAT PF12770.2 KEZ42466.1 - 0.0013 17.8 1.7 0.04 13.0 0.1 3.1 2 1 0 2 2 2 1 CHAT domain SPOB_a PF14689.1 KEZ42466.1 - 0.14 11.7 0.2 8.6 6.0 0.0 3.2 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain rpo132 PF12415.3 KEZ42466.1 - 0.15 10.9 0.3 0.36 9.8 0.2 1.6 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase TPR_2 PF07719.12 KEZ42466.1 - 0.37 10.8 6.3 64 3.8 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KEZ42467.1 - 7.2e-25 87.3 0.0 1.2e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ42467.1 - 1.7e-09 37.4 10.9 2.8e-09 36.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Basic PF01586.11 KEZ42467.1 - 0.64 10.7 5.0 0.15 12.7 0.2 2.5 2 0 0 2 2 2 0 Myogenic Basic domain Kri1 PF05178.7 KEZ42468.1 - 1.7e-25 89.2 27.1 1.7e-25 89.2 18.8 6.5 5 3 2 7 7 7 1 KRI1-like family Kri1_C PF12936.2 KEZ42468.1 - 8.4e-23 80.1 0.1 8.4e-23 80.1 0.1 5.6 5 1 1 6 6 6 1 KRI1-like family C-terminal Ras PF00071.17 KEZ42469.1 - 2e-58 196.3 0.0 2.3e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ42469.1 - 6.6e-20 71.7 0.0 1e-19 71.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ42469.1 - 2.6e-15 56.0 0.0 3.2e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ42469.1 - 1e-08 34.5 0.0 1.2e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEZ42469.1 - 3.9e-07 29.7 0.0 9.5e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEZ42469.1 - 0.00016 21.5 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KEZ42469.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ42469.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain zf-RING_6 PF14835.1 KEZ42470.1 - 0.0018 17.9 7.1 0.0027 17.4 4.9 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 KEZ42470.1 - 0.047 13.3 12.4 0.077 12.6 8.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ42470.1 - 3.3 7.5 14.0 5.4 6.8 9.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 KEZ42471.1 - 1.6e-70 237.2 0.1 2.8e-70 236.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42471.1 - 1.9e-53 181.2 0.1 1.9e-53 181.2 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KEZ42471.1 - 7.4e-23 80.7 0.1 2.2e-22 79.2 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KEZ42471.1 - 1.2e-08 34.2 0.0 2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 KEZ42471.1 - 3.9e-07 30.3 0.1 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 KEZ42471.1 - 0.0008 19.2 1.1 0.011 15.4 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KEZ42471.1 - 0.04 12.7 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Lyase_1 PF00206.15 KEZ42472.1 - 1.9e-61 207.9 0.1 1.3e-49 169.0 0.0 2.1 1 1 1 2 2 2 2 Lyase ASL_C2 PF14698.1 KEZ42472.1 - 2.4e-25 88.3 0.2 4.9e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal GvpG PF05120.7 KEZ42472.1 - 0.074 12.8 0.1 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Gas vesicle protein G DUF4360 PF14273.1 KEZ42473.1 - 1.4e-39 135.6 0.0 1.6e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) zf-CCCH PF00642.19 KEZ42474.1 - 0.03 13.9 0.7 0.03 13.9 0.5 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HypA PF01155.14 KEZ42474.1 - 0.27 10.9 1.5 0.6 9.8 1.0 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family HET PF06985.6 KEZ42475.1 - 4.6e-18 65.7 12.8 3.4e-15 56.4 4.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_28 PF13521.1 KEZ42475.1 - 0.11 12.4 0.1 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KEZ42476.1 - 6.8e-18 65.0 1.5 3.3e-17 62.8 1.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEZ42476.1 - 0.00039 19.3 0.0 0.00077 18.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Daxx PF03344.10 KEZ42476.1 - 0.0092 14.5 17.0 0.015 13.8 11.8 1.2 1 0 0 1 1 1 1 Daxx Family GED PF02212.13 KEZ42476.1 - 0.021 14.7 0.0 0.074 12.9 0.0 1.9 1 0 0 1 1 1 0 Dynamin GTPase effector domain Miro PF08477.8 KEZ42476.1 - 0.033 14.6 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_15 PF13175.1 KEZ42476.1 - 0.058 12.4 0.5 0.14 11.1 0.2 1.7 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KEZ42476.1 - 0.083 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KEZ42476.1 - 0.087 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KEZ42476.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CobT PF06213.7 KEZ42476.1 - 0.27 10.3 18.8 0.48 9.5 13.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 KEZ42476.1 - 0.48 8.4 10.9 0.19 9.8 5.6 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.5 KEZ42476.1 - 0.57 10.1 9.6 1 9.3 6.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_23 PF13476.1 KEZ42476.1 - 0.59 10.4 0.0 0.59 10.4 0.0 2.4 1 1 1 2 2 1 0 AAA domain TRAP_alpha PF03896.11 KEZ42476.1 - 1.5 7.7 11.7 2.3 7.1 8.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIF_alpha PF05793.7 KEZ42476.1 - 1.9 6.7 20.2 3.6 5.8 14.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 KEZ42476.1 - 2.1 6.1 24.6 3.4 5.4 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 KEZ42476.1 - 6.3 5.9 21.6 11 5.2 15.0 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 KEZ42476.1 - 8.5 4.9 23.7 16 4.0 16.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 KEZ42476.1 - 9.8 5.4 17.3 17 4.7 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LysM PF01476.15 KEZ42477.1 - 6.9e-14 51.4 2.0 0.00032 20.5 0.0 3.8 4 0 0 4 4 4 3 LysM domain Glyoxalase_2 PF12681.2 KEZ42478.1 - 0.0011 19.5 0.0 0.016 15.8 0.0 2.5 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 KEZ42478.1 - 0.048 13.6 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ank_2 PF12796.2 KEZ42479.1 - 2.9e-173 562.7 47.9 8.2e-19 67.7 0.1 13.5 4 3 9 15 15 15 15 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ42479.1 - 9.5e-121 388.0 84.1 9.6e-07 28.3 0.0 30.6 30 1 1 31 31 31 26 Ankyrin repeat Ank_4 PF13637.1 KEZ42479.1 - 7e-112 364.0 45.6 7.6e-09 35.8 0.0 23.1 10 7 16 26 26 26 21 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ42479.1 - 5e-90 286.3 54.3 0.00073 19.5 0.0 30.6 32 0 0 32 32 32 21 Ankyrin repeat Ank_5 PF13857.1 KEZ42479.1 - 1.2e-69 228.7 58.0 9.6e-07 28.8 0.0 22.5 9 6 17 26 26 26 19 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ42479.1 - 3.1e-07 30.1 0.0 6.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RVP PF00077.15 KEZ42479.1 - 0.0011 18.8 1.9 13 5.8 0.0 6.9 5 3 3 8 8 8 1 Retroviral aspartyl protease DUF3447 PF11929.3 KEZ42479.1 - 0.0014 18.3 0.0 5.8 6.8 0.0 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF3447) Shigella_OspC PF06128.6 KEZ42479.1 - 0.0039 16.7 4.4 0.82 9.1 0.7 5.4 4 1 1 5 5 5 2 Shigella flexneri OspC protein AAA_14 PF13173.1 KEZ42479.1 - 0.023 14.5 0.1 0.57 10.0 0.1 2.5 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 KEZ42480.1 - 1.6e-25 89.9 0.0 2.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KEZ42480.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase adh_short PF00106.20 KEZ42482.1 - 6.1e-21 75.0 0.6 1.1e-20 74.1 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ42482.1 - 2.5e-08 34.0 0.0 4.4e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ42482.1 - 0.00052 19.7 0.5 0.011 15.4 0.1 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 KEZ42482.1 - 0.019 14.3 0.1 0.051 13.0 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEZ42482.1 - 0.03 14.3 0.1 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding TrkA_N PF02254.13 KEZ42482.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain PAP2 PF01569.16 KEZ42483.1 - 2.1e-18 66.2 5.3 2.1e-18 66.2 3.6 2.5 2 2 0 2 2 2 1 PAP2 superfamily Fungal_trans PF04082.13 KEZ42484.1 - 0.024 13.5 0.0 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.20 KEZ42485.1 - 4.9e-27 94.8 0.4 8.5e-27 94.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ42485.1 - 8.6e-12 45.0 0.2 1.3e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ42485.1 - 2.8e-11 43.3 0.2 5.3e-11 42.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KEZ42485.1 - 1.6e-10 41.1 0.2 9.8e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ42485.1 - 0.00045 20.2 0.3 0.0011 18.9 0.1 1.8 2 1 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 KEZ42485.1 - 0.0018 17.5 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 KEZ42485.1 - 0.01 14.7 0.2 0.021 13.7 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KEZ42485.1 - 0.032 13.1 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Tub_2 PF04525.7 KEZ42486.1 - 5.1e-26 91.2 0.1 6.3e-26 90.9 0.1 1.0 1 0 0 1 1 1 1 Tubby C 2 Vps16_N PF04841.8 KEZ42486.1 - 0.057 11.9 0.1 0.074 11.5 0.0 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region Glyco_hydro_61 PF03443.9 KEZ42487.1 - 2.7e-53 181.0 0.0 3.2e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RrnaAD PF00398.15 KEZ42488.1 - 1.9e-59 200.8 0.0 2.5e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KEZ42488.1 - 2.2e-09 37.3 0.0 3.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42488.1 - 1.9e-06 28.4 0.0 3.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ42488.1 - 0.0016 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEZ42488.1 - 0.0026 17.3 0.0 0.0068 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KEZ42488.1 - 0.0058 16.0 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KEZ42488.1 - 0.0088 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KEZ42488.1 - 0.026 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42488.1 - 0.029 14.8 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2373 PF10180.4 KEZ42488.1 - 0.036 13.5 0.2 0.96 9.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) UPF0020 PF01170.13 KEZ42488.1 - 0.12 11.9 0.0 0.31 10.5 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DREV PF05219.7 KEZ42488.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FPN1 PF06963.7 KEZ42489.1 - 7.5e-120 400.2 12.5 9e-120 399.9 8.7 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Pkinase PF00069.20 KEZ42490.1 - 9.4e-16 57.7 0.0 1.3e-14 54.0 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42490.1 - 0.00013 21.0 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42490.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KEZ42490.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ42490.1 - 0.048 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KEZ42490.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_6 PF12697.2 KEZ42491.1 - 1.2e-11 45.0 0.3 1.8e-11 44.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ42491.1 - 0.0077 15.8 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Kri1 PF05178.7 KEZ42491.1 - 0.04 14.2 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 KRI1-like family Abhydrolase_5 PF12695.2 KEZ42491.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KEZ42492.1 - 3.4e-37 127.9 14.2 4.4e-37 127.6 9.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 KEZ42492.1 - 0.016 15.1 4.0 0.016 15.1 2.8 3.8 4 1 0 4 4 4 0 Short repeat of unknown function (DUF308) Cation_ATPase_C PF00689.16 KEZ42492.1 - 0.042 13.3 5.7 0.24 10.8 0.0 3.2 3 1 0 3 3 3 0 Cation transporting ATPase, C-terminus FMO-like PF00743.14 KEZ42493.1 - 2.2e-28 98.7 0.0 2e-15 55.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEZ42493.1 - 5.9e-19 68.9 0.1 2.1e-17 63.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ42493.1 - 1.8e-09 36.9 0.6 7.2e-07 28.4 0.0 3.0 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEZ42493.1 - 7.7e-07 29.1 0.0 0.00013 21.9 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ42493.1 - 2.9e-05 23.8 0.0 0.00069 19.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEZ42493.1 - 0.00011 22.1 0.3 0.0004 20.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ42493.1 - 0.03 13.4 0.1 0.077 12.0 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KEZ42493.1 - 0.084 11.7 0.5 1.3 7.7 0.0 2.5 2 1 1 3 3 3 0 FAD dependent oxidoreductase HET PF06985.6 KEZ42494.1 - 1.5e-12 47.8 0.0 3.7e-12 46.5 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4448 PF14610.1 KEZ42495.1 - 6.8e-26 90.9 0.0 9.8e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KEZ42495.1 - 4.3e-05 22.7 2.3 8.3e-05 21.8 1.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.1 KEZ42495.1 - 0.11 12.4 0.1 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein melan-A DUF1625 PF07787.7 KEZ42495.1 - 0.18 11.0 0.1 5.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) AAA PF00004.24 KEZ42496.1 - 1e-16 61.3 0.0 1.9e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ42496.1 - 1.4e-05 25.8 0.0 5.9e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEZ42496.1 - 0.00071 19.7 0.0 0.0056 16.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEZ42496.1 - 0.0022 17.7 0.0 0.0089 15.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEZ42496.1 - 0.0022 17.9 0.1 0.0072 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KEZ42496.1 - 0.0028 17.9 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ42496.1 - 0.0083 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 KEZ42496.1 - 0.023 14.1 0.0 0.1 12.0 0.0 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_33 PF13671.1 KEZ42496.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TFIIB PF00382.14 KEZ42496.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat TPR_12 PF13424.1 KEZ42497.1 - 5.3e-13 48.7 5.3 5.4e-05 23.0 0.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ42497.1 - 4.3e-08 32.6 4.0 0.0012 18.4 0.1 5.0 4 2 1 5 5 5 3 TPR repeat TPR_1 PF00515.23 KEZ42497.1 - 6.6e-07 28.6 0.7 0.0091 15.5 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ42497.1 - 1.8e-06 27.4 8.2 0.65 10.0 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ42497.1 - 8.7e-06 25.1 0.1 0.023 14.4 0.0 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ42497.1 - 1.3e-05 25.1 0.1 0.3 11.6 0.0 3.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ42497.1 - 4.8e-05 23.6 12.0 0.85 10.4 0.0 7.2 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ42497.1 - 0.00019 21.9 8.1 0.0017 18.9 0.0 4.6 5 1 0 5 5 3 1 Tetratricopeptide repeat Ank_4 PF13637.1 KEZ42497.1 - 0.00047 20.6 0.0 0.0015 18.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KEZ42497.1 - 0.00068 19.3 0.0 0.79 9.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KEZ42497.1 - 0.0011 19.2 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TPR_7 PF13176.1 KEZ42497.1 - 0.0021 17.7 5.9 0.006 16.2 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat Ank_3 PF13606.1 KEZ42497.1 - 0.0054 16.8 0.1 7.2 7.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 KEZ42497.1 - 0.006 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TPR_10 PF13374.1 KEZ42497.1 - 0.0068 16.3 14.8 0.11 12.4 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ42497.1 - 0.012 15.9 0.0 3.8 7.9 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.6 KEZ42497.1 - 0.041 14.0 0.4 0.15 12.2 0.3 1.8 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) TPR_9 PF13371.1 KEZ42497.1 - 0.089 12.6 8.9 0.73 9.7 0.0 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ42497.1 - 0.31 11.5 4.9 1.5e+02 3.1 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Glyco_hydro_65C PF03633.10 KEZ42498.1 - 0.00079 19.4 0.6 0.019 15.0 0.0 3.2 3 0 0 3 3 3 1 Glycosyl hydrolase family 65, C-terminal domain DUF3060 PF11259.3 KEZ42498.1 - 0.017 14.7 19.4 0.12 11.9 1.0 4.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3060) Cellulase PF00150.13 KEZ42499.1 - 2.4e-22 79.4 5.2 3.2e-22 79.0 3.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 KEZ42499.1 - 1.6e-08 34.8 0.0 5.4e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KEZ42499.1 - 2.6e-07 29.8 0.0 8.4e-05 21.6 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KEZ42499.1 - 0.00056 19.1 4.2 0.0026 16.9 0.0 2.6 2 1 0 2 2 2 1 Beta-galactosidase DUF4066 PF13278.1 KEZ42503.1 - 6.7e-22 77.5 0.0 9.9e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEZ42503.1 - 3.2e-12 46.1 0.0 1.1e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family CorA PF01544.13 KEZ42504.1 - 1.4e-11 44.0 0.5 3.2e-11 42.7 0.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Tyrosinase PF00264.15 KEZ42505.1 - 2.6e-31 109.5 0.1 4e-31 108.9 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.16 KEZ42506.1 - 3.2e-14 52.5 1.4 2.3e-13 49.8 1.0 2.1 1 1 0 1 1 1 1 Dioxygenase CorA PF01544.13 KEZ42507.1 - 3.3e-05 23.0 2.0 9.7e-05 21.5 1.3 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4381 PF14316.1 KEZ42507.1 - 0.039 14.0 1.0 0.18 11.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) UbiA PF01040.13 KEZ42507.1 - 0.056 12.6 0.2 0.096 11.8 0.2 1.3 1 0 0 1 1 1 0 UbiA prenyltransferase family Chromate_transp PF02417.10 KEZ42507.1 - 0.059 12.9 0.4 0.81 9.2 0.3 2.1 1 1 1 2 2 2 0 Chromate transporter EB1 PF03271.12 KEZ42507.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 EB1-like C-terminal motif MU117 PF15474.1 KEZ42509.1 - 0.00032 21.1 1.8 0.00084 19.7 0.6 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene family B5 PF03484.10 KEZ42509.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase B5 domain Lipoprotein_Ltp PF07553.6 KEZ42510.1 - 0.021 14.7 0.9 0.055 13.3 0.0 2.0 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein MFS_1 PF07690.11 KEZ42511.1 - 1.5e-07 30.4 8.1 1.9e-07 30.1 5.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ42511.1 - 0.016 13.6 3.7 0.023 13.0 2.6 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein p450 PF00067.17 KEZ42514.1 - 1.6e-15 56.6 0.0 1.8e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.17 KEZ42515.1 - 1.3e-71 241.9 0.0 1.8e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase AAA_16 PF13191.1 KEZ42516.1 - 5.6e-07 29.7 0.0 2.9e-06 27.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KEZ42516.1 - 0.00075 19.1 0.0 0.0025 17.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain ZZ PF00569.12 KEZ42516.1 - 0.0054 16.2 5.0 0.012 15.0 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type AAA_22 PF13401.1 KEZ42516.1 - 0.0099 16.0 0.4 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain PLAC8 PF04749.12 KEZ42517.1 - 2.3e-24 86.0 10.6 2.9e-24 85.6 7.4 1.1 1 0 0 1 1 1 1 PLAC8 family AIRC PF00731.15 KEZ42519.1 - 2.1e-60 202.3 3.5 2.9e-60 201.9 1.5 2.0 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 KEZ42519.1 - 4.1e-52 176.0 0.0 7e-52 175.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KEZ42519.1 - 2e-15 57.0 0.1 4.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEZ42519.1 - 1.1e-08 34.7 0.0 2.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 KEZ42519.1 - 2.1e-07 30.4 0.9 3e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KEZ42519.1 - 3.7e-05 22.6 0.0 0.01 14.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon XdhC_C PF13478.1 KEZ42519.1 - 0.036 14.3 0.7 1.8 8.9 0.0 3.1 3 1 0 3 3 3 0 XdhC Rossmann domain FA_hydroxylase PF04116.8 KEZ42520.1 - 4e-18 65.8 12.2 4e-18 65.8 8.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4282 PF14110.1 KEZ42520.1 - 0.16 12.1 2.8 0.45 10.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) YL1 PF05764.8 KEZ42522.1 - 1.6e-58 198.1 26.4 1.6e-58 198.1 18.3 3.0 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 KEZ42522.1 - 4.5e-14 51.6 2.4 2.2e-13 49.4 0.4 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 KEZ42522.1 - 0.47 10.1 0.0 0.47 10.1 0.0 2.2 3 0 0 3 3 3 0 HIT zinc finger SNF2_N PF00176.18 KEZ42523.1 - 0.0099 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VPS9 PF02204.13 KEZ42524.1 - 3.6e-24 84.7 0.0 6.7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CH PF00307.26 KEZ42525.1 - 5.5e-38 129.3 0.3 8.8e-19 67.5 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KEZ42525.1 - 3.6e-25 87.7 5.3 1e-24 86.2 0.1 3.7 4 0 0 4 4 4 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KEZ42525.1 - 2.2e-11 43.2 0.9 3.2e-07 29.9 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 KEZ42525.1 - 0.0005 19.7 0.5 0.0085 15.9 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 KEZ42525.1 - 0.004 16.7 0.7 0.11 12.0 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain pair Spectrin PF00435.16 KEZ42525.1 - 0.0073 16.5 11.6 0.081 13.2 2.6 2.8 3 0 0 3 3 3 2 Spectrin repeat DUF1943 PF09172.6 KEZ42525.1 - 0.012 14.5 0.1 0.04 12.7 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1943) EF-hand_1 PF00036.27 KEZ42525.1 - 0.031 13.5 0.2 0.54 9.6 0.0 2.8 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 KEZ42525.1 - 0.17 12.0 2.5 0.93 9.6 1.7 2.3 1 0 0 1 1 1 0 EF-hand domain pair FAD-oxidase_C PF02913.14 KEZ42526.1 - 6.5e-62 209.0 0.0 9.1e-62 208.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEZ42526.1 - 1.2e-36 125.2 0.6 3e-36 123.9 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 KEZ42527.1 - 1.4e-07 31.3 12.1 2.5e-07 30.4 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1908 PF08926.6 KEZ42527.1 - 0.15 10.8 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Proteasome PF00227.21 KEZ42528.1 - 1.1e-54 184.6 0.1 1.6e-54 184.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEZ42528.1 - 9.7e-13 47.1 0.1 1.8e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature IL6 PF00489.12 KEZ42528.1 - 0.12 11.9 0.1 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 Interleukin-6/G-CSF/MGF family zf-CHY PF05495.7 KEZ42529.1 - 1.3e-14 54.0 19.1 1.7e-14 53.7 13.2 1.1 1 0 0 1 1 1 1 CHY zinc finger PAZ_siRNAbind PF12212.3 KEZ42529.1 - 0.091 12.3 0.1 5.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Piwi/Argonaute/Zwille siRNA-binding domain Tmemb_55A PF09788.4 KEZ42529.1 - 0.5 9.4 7.5 0.58 9.2 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A zf-RING_3 PF14369.1 KEZ42529.1 - 0.68 9.9 9.5 1.6 8.7 4.4 2.5 1 1 1 2 2 2 0 zinc-finger DUF3797 PF12677.2 KEZ42529.1 - 0.73 9.4 0.0 0.73 9.4 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF3797) Zn_Tnp_IS1595 PF12760.2 KEZ42529.1 - 1.1 9.0 11.8 16 5.4 5.6 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KEZ42529.1 - 1.8 8.6 14.5 5 7.2 4.3 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain Cytochrome_C7 PF14522.1 KEZ42529.1 - 3 7.5 14.1 4.9 6.8 9.7 1.4 1 0 0 1 1 1 0 Cytochrome c7 HypA PF01155.14 KEZ42529.1 - 3.6 7.2 11.6 0.17 11.5 2.8 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family RNA_POL_M_15KD PF02150.11 KEZ42529.1 - 8.3 6.1 10.6 17 5.2 0.1 3.3 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit TrkH PF02386.11 KEZ42530.1 - 5e-111 370.6 18.6 3.1e-108 361.4 9.5 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L19 PF01245.15 KEZ42531.1 - 5.2e-16 58.4 0.0 1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.20 KEZ42533.1 - 1.2e-60 205.3 0.3 1.4e-60 205.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.20 KEZ42534.1 - 2.7e-07 30.1 3.5 2.7e-07 30.1 2.4 5.5 5 2 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ42534.1 - 4.1e-07 29.7 4.9 4.1e-07 29.7 3.4 4.6 4 3 0 4 4 2 1 Ring finger domain zf-RING_6 PF14835.1 KEZ42534.1 - 1.7e-06 27.6 0.3 1.7e-06 27.6 0.2 3.5 3 1 0 3 3 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 KEZ42534.1 - 3.6e-06 26.8 4.1 3.6e-06 26.8 2.8 5.8 4 3 1 5 5 4 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 KEZ42534.1 - 1.3e-05 24.6 0.1 1.3e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain zf-RING_5 PF14634.1 KEZ42534.1 - 1.8e-05 24.3 2.9 1.8e-05 24.3 2.0 5.7 6 1 0 6 6 4 1 zinc-RING finger domain SH3_1 PF00018.23 KEZ42534.1 - 0.00027 20.2 0.0 0.00066 19.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain zf-C3HC4_4 PF15227.1 KEZ42534.1 - 0.00057 19.7 3.9 0.00057 19.7 2.7 5.0 5 3 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KEZ42534.1 - 0.0014 18.3 1.3 0.0014 18.3 0.9 2.1 2 0 0 2 2 1 1 RING-type zinc-finger SH3_2 PF07653.12 KEZ42534.1 - 0.0051 16.2 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Band_7 PF01145.20 KEZ42534.1 - 1.8 8.4 5.7 3.1 7.6 3.9 1.3 1 0 0 1 1 1 0 SPFH domain / Band 7 family ECH PF00378.15 KEZ42535.1 - 1.2e-69 234.1 0.1 1.5e-69 233.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KEZ42535.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 KEZ42536.1 - 1.4e-60 203.9 1.7 1.7e-60 203.6 1.2 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.8 KEZ42537.1 - 5.7e-53 180.2 0.1 1.9e-52 178.5 0.1 1.7 1 1 0 1 1 1 1 Paf1 HeLo PF14479.1 KEZ42538.1 - 4.9e-42 144.0 0.1 1.5e-41 142.4 0.0 1.9 2 0 0 2 2 2 1 Prion-inhibition and propagation TPR_11 PF13414.1 KEZ42538.1 - 2.5e-19 68.6 5.9 1.2e-14 53.7 1.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEZ42538.1 - 6.1e-10 38.2 9.3 0.00063 19.2 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ42538.1 - 1.9e-09 36.6 10.5 7.6e-05 22.3 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ42538.1 - 2.7e-05 24.4 0.4 0.0082 16.6 0.1 3.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ42538.1 - 0.00014 22.4 6.5 0.0048 17.5 2.6 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ42538.1 - 0.0013 18.5 5.3 0.032 14.1 1.4 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ42538.1 - 0.0025 17.8 0.4 2 8.8 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ42538.1 - 0.0068 16.7 4.1 0.068 13.5 1.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ42538.1 - 0.0069 16.1 0.3 5.8 6.9 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ42538.1 - 0.13 12.0 6.9 0.3 10.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ42538.1 - 4.2 8.0 7.3 0.72 10.4 0.3 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Ribosomal_S8 PF00410.14 KEZ42539.1 - 1.2e-25 89.8 0.0 1.6e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.21 KEZ42540.1 - 5.1e-29 99.6 0.7 6.8e-29 99.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rotamase_3 PF13616.1 KEZ42541.1 - 7e-18 64.9 0.4 1.4e-17 64.0 0.3 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KEZ42541.1 - 3.7e-16 59.6 0.0 3.7e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEZ42541.1 - 0.00013 22.5 0.0 0.00013 22.5 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain SAD_SRA PF02182.12 KEZ42542.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 SAD/SRA domain TruD PF01142.13 KEZ42543.1 - 7.5e-53 179.5 0.0 1.7e-49 168.5 0.0 3.3 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.20 KEZ42544.1 - 8.3e-59 198.8 0.0 1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42544.1 - 1.3e-34 119.4 0.0 1.7e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42544.1 - 1.1e-07 31.0 0.0 1.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ42545.1 - 3e-16 59.8 0.0 1.1e-15 58.0 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KEZ42545.1 - 1.7e-05 23.6 0.0 2.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 KEZ42545.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 KEZ42545.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PTPLA PF04387.9 KEZ42546.1 - 3.5e-55 185.9 8.5 6.8e-55 184.9 5.9 1.5 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA MBT PF02820.13 KEZ42546.1 - 0.19 11.6 0.5 0.67 9.9 0.0 1.9 2 0 0 2 2 2 0 mbt repeat DUF676 PF05057.9 KEZ42547.1 - 0.00015 21.1 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KEZ42547.1 - 0.0002 21.1 0.6 0.0025 17.5 0.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ42547.1 - 0.00038 20.1 0.0 0.00076 19.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEZ42547.1 - 0.017 15.0 0.9 0.068 13.0 0.6 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KEZ42547.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RIX1 PF08167.7 KEZ42548.1 - 3.9e-35 120.9 1.6 3.9e-35 120.9 1.1 2.8 3 2 0 3 3 3 1 rRNA processing/ribosome biogenesis TPR_8 PF13181.1 KEZ42549.1 - 3.4e-06 26.4 0.6 0.00036 20.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ42549.1 - 1.1e-05 25.0 5.1 0.15 11.6 0.0 5.4 5 1 1 6 6 6 2 TPR repeat TPR_14 PF13428.1 KEZ42549.1 - 9.9e-05 22.6 15.4 0.09 13.4 0.1 6.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ42549.1 - 0.00013 21.6 18.9 0.039 13.8 0.1 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ42549.1 - 0.00014 21.7 0.7 0.29 11.4 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ42549.1 - 0.00083 18.8 3.6 0.52 10.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ42549.1 - 0.00085 19.6 0.1 0.03 14.6 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ42549.1 - 0.0014 18.2 0.8 2.3 8.1 0.1 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ42549.1 - 0.0025 18.4 12.0 1.3 9.7 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ42549.1 - 4.3 7.3 11.0 41 4.2 0.0 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ42549.1 - 5.2 7.7 5.5 3.4 8.3 0.1 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat Methyltransf_PK PF05891.7 KEZ42550.1 - 4.6e-59 199.3 0.0 5.3e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KEZ42550.1 - 0.0037 17.0 0.0 0.0049 16.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42550.1 - 0.0071 16.9 0.0 0.0093 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain SGL PF08450.7 KEZ42551.1 - 5.1e-67 225.8 0.0 6.1e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KEZ42551.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Arylesterase PF01731.15 KEZ42551.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Arylesterase DUF1850 PF08905.6 KEZ42551.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) PD40 PF07676.7 KEZ42551.1 - 0.11 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Aldedh PF00171.17 KEZ42552.1 - 1.5e-173 577.4 0.1 1.8e-173 577.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEZ42552.1 - 0.09 11.9 0.1 1.6 7.9 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1487) DUF4407 PF14362.1 KEZ42555.1 - 1.9 7.4 12.3 2.8 6.8 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FLO_LFY PF01698.11 KEZ42555.1 - 2.3 6.9 21.7 3.2 6.5 15.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Borrelia_P83 PF05262.6 KEZ42555.1 - 3.5 5.7 31.5 4.3 5.5 21.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.5 KEZ42555.1 - 4.6 6.3 51.4 7.2 5.7 35.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.10 KEZ42555.1 - 4.9 5.6 22.5 6.6 5.2 15.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 KEZ42555.1 - 5.6 4.7 43.7 7.8 4.2 30.3 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M18 PF02127.10 KEZ42556.1 - 2.4e-170 566.7 0.0 2.9e-170 566.4 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KEZ42556.1 - 9.5e-07 27.8 0.0 0.00019 20.3 0.0 2.4 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase PDZ_1 PF12812.2 KEZ42556.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 PDZ-like domain Med15_fungi PF05397.7 KEZ42557.1 - 4.9e-05 23.2 4.7 0.0017 18.2 0.0 4.5 4 0 0 4 4 4 2 Mediator complex subunit 15 Whi5 PF08528.6 KEZ42558.1 - 5.5e-07 29.0 0.1 1.1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Whi5 like DUF4200 PF13863.1 KEZ42559.1 - 0.31 11.0 8.2 0.34 10.8 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 KEZ42559.1 - 0.45 10.3 4.3 13 5.6 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HR1 PF02185.11 KEZ42559.1 - 0.98 9.2 8.2 11 5.7 0.8 3.8 4 1 0 4 4 4 0 Hr1 repeat IncA PF04156.9 KEZ42559.1 - 8.2 5.9 7.4 30 4.1 3.9 2.2 2 0 0 2 2 2 0 IncA protein RTA1 PF04479.8 KEZ42560.1 - 2.7e-35 121.9 9.1 4.2e-35 121.2 6.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Xpo1 PF08389.7 KEZ42563.1 - 1.9e-35 121.9 2.5 2.7e-34 118.2 0.1 3.7 3 1 0 3 3 3 1 Exportin 1-like protein HsbA PF12296.3 KEZ42563.1 - 9.6e-08 31.9 8.7 4.8e-07 29.6 6.0 2.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A HEAT PF02985.17 KEZ42563.1 - 0.0039 17.1 0.0 11 6.3 0.0 3.8 2 0 0 2 2 2 2 HEAT repeat CorA PF01544.13 KEZ42564.1 - 7.6e-05 21.8 0.1 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein LMBR1 PF04791.11 KEZ42565.1 - 2.9e-22 78.9 16.1 1.4e-21 76.6 11.2 1.8 1 1 0 1 1 1 1 LMBR1-like membrane protein Hat1_N PF10394.4 KEZ42566.1 - 2.9e-33 115.2 0.0 4.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 KEZ42566.1 - 0.038 14.1 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEZ42566.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CTK3 PF12243.3 KEZ42567.1 - 2.9e-53 179.2 1.7 4.2e-53 178.7 1.2 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KEZ42567.1 - 2.7e-16 59.3 13.4 2.7e-16 59.3 9.3 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 KEZ42567.1 - 0.006 16.3 0.2 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein ImcF-related_N PF14331.1 KEZ42567.1 - 0.037 12.9 0.5 0.078 11.8 0.3 1.5 1 0 0 1 1 1 0 ImcF-related N-terminal domain DUF3873 PF12989.2 KEZ42567.1 - 0.081 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Ribosomal_L12 PF00542.14 KEZ42568.1 - 3.3e-20 71.8 4.6 4.1e-19 68.3 1.9 2.4 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain AAA_5 PF07728.9 KEZ42569.1 - 5.1e-127 418.2 0.1 6.2e-22 77.8 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 KEZ42569.1 - 1.1e-29 103.3 0.2 0.00015 21.9 0.0 7.8 8 0 0 8 8 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 KEZ42569.1 - 5.8e-29 100.3 0.0 1e-09 38.0 0.0 7.2 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ42569.1 - 6.7e-27 94.7 0.0 5.4e-05 24.0 0.0 7.9 6 0 0 6 6 6 5 AAA domain AAA_33 PF13671.1 KEZ42569.1 - 4.2e-25 88.2 0.0 0.00058 19.7 0.0 7.5 6 2 0 6 6 6 4 AAA domain AAA_16 PF13191.1 KEZ42569.1 - 2.6e-24 86.2 31.0 2.1e-05 24.6 0.1 9.2 9 1 0 9 9 8 5 AAA ATPase domain AAA_22 PF13401.1 KEZ42569.1 - 1.1e-23 83.8 1.7 0.011 15.9 0.0 8.8 8 1 0 8 8 7 6 AAA domain AAA_18 PF13238.1 KEZ42569.1 - 5.5e-21 75.2 0.1 0.0045 17.2 0.0 7.5 6 0 0 6 6 6 4 AAA domain AAA_14 PF13173.1 KEZ42569.1 - 2.1e-20 72.9 0.0 0.00026 20.8 0.0 7.9 8 0 0 8 8 7 3 AAA domain Sigma54_activ_2 PF14532.1 KEZ42569.1 - 3.3e-20 72.5 0.7 0.0007 19.6 0.0 7.8 8 0 0 8 8 6 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 KEZ42569.1 - 5.2e-19 68.3 0.0 0.017 14.6 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain T2SE PF00437.15 KEZ42569.1 - 2.7e-17 62.5 3.3 0.0027 16.6 0.0 6.5 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_19 PF13245.1 KEZ42569.1 - 1.1e-16 60.2 7.0 0.0069 16.1 0.0 6.7 6 0 0 6 6 6 4 Part of AAA domain Zeta_toxin PF06414.7 KEZ42569.1 - 4.1e-15 55.4 2.7 0.0031 16.6 0.0 7.3 7 0 0 7 7 7 2 Zeta toxin ABC_tran PF00005.22 KEZ42569.1 - 5.2e-15 55.9 2.0 0.0099 16.1 0.0 7.6 6 0 0 6 6 6 2 ABC transporter RNA_helicase PF00910.17 KEZ42569.1 - 2.4e-14 53.4 1.4 0.28 11.3 0.0 6.7 6 0 0 6 6 6 3 RNA helicase NACHT PF05729.7 KEZ42569.1 - 1.2e-13 51.0 7.2 0.16 11.5 0.1 7.2 7 0 0 7 7 6 4 NACHT domain UPF0079 PF02367.12 KEZ42569.1 - 1.5e-13 50.4 4.0 0.17 11.4 0.0 6.4 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 KEZ42569.1 - 2.7e-13 49.5 1.0 4.6 6.3 0.0 9.6 10 0 0 10 10 10 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEZ42569.1 - 1.6e-12 47.6 6.2 0.3 11.0 0.0 7.8 7 0 0 7 7 6 2 AAA domain AAA_25 PF13481.1 KEZ42569.1 - 2.1e-12 46.8 0.1 0.67 9.3 0.0 6.1 5 0 0 5 5 5 4 AAA domain AAA_29 PF13555.1 KEZ42569.1 - 2.5e-12 46.1 1.0 0.41 10.2 0.0 6.6 6 0 0 6 6 6 2 P-loop containing region of AAA domain RuvB_N PF05496.7 KEZ42569.1 - 7.9e-12 44.7 0.8 0.028 13.4 0.0 6.4 6 0 0 6 6 5 2 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KEZ42569.1 - 1.3e-11 43.9 5.6 0.19 10.8 0.1 6.2 6 0 0 6 6 6 4 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 KEZ42569.1 - 4.8e-10 39.1 0.0 0.072 12.5 0.0 6.4 7 0 0 7 7 6 1 IstB-like ATP binding protein SRP54 PF00448.17 KEZ42569.1 - 5.7e-10 38.9 1.6 0.33 10.3 0.0 5.7 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain MobB PF03205.9 KEZ42569.1 - 4.6e-09 36.1 5.6 1 9.0 0.1 6.5 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KEZ42569.1 - 9.2e-09 34.9 1.1 0.02 14.4 0.0 5.6 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.10 KEZ42569.1 - 9.7e-09 34.4 2.0 0.12 10.9 0.0 5.6 6 0 0 6 6 6 2 Rad17 cell cycle checkpoint protein Miro PF08477.8 KEZ42569.1 - 1.5e-08 35.1 2.9 8.1 6.9 0.1 6.8 6 0 0 6 6 6 0 Miro-like protein NTPase_1 PF03266.10 KEZ42569.1 - 1e-06 28.5 7.1 0.91 9.2 0.0 5.9 5 0 0 5 5 5 2 NTPase Viral_helicase1 PF01443.13 KEZ42569.1 - 1.6e-06 27.8 0.2 0.025 14.1 0.0 5.3 5 0 0 5 5 5 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 KEZ42569.1 - 2e-06 26.8 4.6 1 8.1 0.0 5.6 6 0 0 6 6 6 2 NB-ARC domain ResIII PF04851.10 KEZ42569.1 - 6.4e-06 26.1 0.1 1.2 8.9 0.0 5.3 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KEZ42569.1 - 1.2e-05 24.9 3.8 6.1 6.3 0.0 6.5 7 0 0 7 7 6 0 AAA domain MMR_HSR1 PF01926.18 KEZ42569.1 - 2.8e-05 24.0 2.8 60 3.6 0.0 6.9 7 0 0 7 7 6 0 50S ribosome-binding GTPase TIP49 PF06068.8 KEZ42569.1 - 2.9e-05 22.9 0.3 4.4 5.9 0.0 4.8 5 0 0 5 5 5 0 TIP49 C-terminus CbiA PF01656.18 KEZ42569.1 - 7.7e-05 22.1 2.3 0.31 10.4 0.0 5.0 6 0 0 6 6 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.12 KEZ42569.1 - 0.00017 21.2 10.8 4.5 6.7 0.1 6.6 7 0 0 7 7 7 0 Conserved hypothetical ATP binding protein cobW PF02492.14 KEZ42569.1 - 0.00038 19.9 7.7 4.2 6.7 0.0 5.8 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 KEZ42569.1 - 0.00041 19.5 0.1 1.9 7.5 0.0 4.6 5 0 0 5 5 5 1 KaiC AAA_7 PF12775.2 KEZ42569.1 - 0.00078 18.6 1.0 5.7 5.9 0.0 4.9 6 0 0 6 6 5 0 P-loop containing dynein motor region D3 AAA_6 PF12774.2 KEZ42569.1 - 0.0064 16.0 0.0 2.8 7.3 0.0 4.3 6 0 0 6 6 4 1 Hydrolytic ATP binding site of dynein motor region D1 PRK PF00485.13 KEZ42569.1 - 0.011 15.3 0.4 8.8 5.8 0.0 4.1 5 0 0 5 5 4 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 KEZ42569.1 - 0.015 14.4 8.4 0.29 10.3 0.0 5.7 7 0 0 7 7 6 0 Chromatin associated protein KTI12 tRNA_lig_kinase PF08303.6 KEZ42569.1 - 0.027 14.3 2.2 0.43 10.4 0.0 3.3 3 0 0 3 3 2 0 tRNA ligase kinase domain PhoH PF02562.11 KEZ42569.1 - 0.039 13.1 0.6 10 5.2 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein Parvo_NS1 PF01057.12 KEZ42569.1 - 0.16 10.8 0.0 19 4.0 0.0 3.0 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 DBI_PRT PF02277.12 KEZ42569.1 - 0.23 10.5 0.4 10 5.1 0.0 2.8 3 0 0 3 3 3 0 Phosphoribosyltransferase DUF4156 PF13698.1 KEZ42569.1 - 0.3 11.0 0.0 0.87 9.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) bZIP_1 PF00170.16 KEZ42570.1 - 9.2e-06 25.5 7.4 9.2e-06 25.5 5.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ42570.1 - 0.34 10.7 10.4 0.16 11.8 4.9 2.0 2 0 0 2 2 2 0 Basic region leucine zipper GRP PF07172.6 KEZ42572.1 - 0.013 15.9 14.6 0.013 15.9 10.1 1.8 2 0 0 2 2 2 0 Glycine rich protein family PBP1_TM PF14812.1 KEZ42573.1 - 1.3 9.4 6.9 2.5 8.4 4.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal E1-E2_ATPase PF00122.15 KEZ42574.1 - 7.1e-57 192.0 0.1 7.1e-57 192.0 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ42574.1 - 1.2e-45 155.3 13.2 4.7e-45 153.3 8.0 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ42574.1 - 1.7e-28 100.4 0.0 7e-28 98.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ42574.1 - 4.4e-17 61.8 0.0 9.1e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ42574.1 - 1.2e-14 54.9 0.0 3.4e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ42574.1 - 4.9e-07 29.5 0.3 0.00028 20.5 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ42574.1 - 7.9e-07 28.4 0.0 1.2e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF3325 PF11804.3 KEZ42574.1 - 0.0017 18.2 1.1 0.19 11.6 0.0 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) DUF21 PF01595.15 KEZ42574.1 - 0.0091 15.3 0.6 0.0091 15.3 0.4 3.3 3 1 0 3 3 3 1 Domain of unknown function DUF21 Med10 PF09748.4 KEZ42575.1 - 1.2e-39 135.0 0.0 1.3e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex TPR_11 PF13414.1 KEZ42576.1 - 1.4e-51 171.9 13.9 1.2e-21 76.0 2.5 6.0 4 2 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 KEZ42576.1 - 3e-40 134.2 6.4 3.9e-08 32.5 0.1 8.6 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ42576.1 - 7.6e-40 131.6 6.4 3.8e-06 26.3 0.1 8.7 8 1 1 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.26 KEZ42576.1 - 1.3e-28 98.4 4.1 1.3e-28 98.4 2.8 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.1 KEZ42576.1 - 7.1e-28 96.6 4.0 4.1e-09 36.8 0.4 6.4 3 3 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ42576.1 - 1.8e-24 85.8 7.8 6e-08 32.9 0.0 5.9 4 3 3 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ42576.1 - 5.9e-23 79.2 12.2 6.6e-05 23.1 0.2 8.7 4 3 5 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ42576.1 - 3.2e-19 67.4 6.1 0.00032 20.6 0.3 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ42576.1 - 2.2e-17 61.4 7.9 0.0007 19.2 0.0 8.2 6 2 2 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KEZ42576.1 - 3.7e-17 62.2 0.3 1.5e-08 34.6 0.0 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEZ42576.1 - 1e-16 60.6 10.0 0.00059 19.7 0.1 5.9 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ42576.1 - 7.5e-14 50.3 4.5 0.082 12.7 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ42576.1 - 2.3e-12 46.6 7.0 0.002 17.9 0.1 4.9 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ42576.1 - 3.3e-09 36.2 4.2 0.0042 16.2 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ42576.1 - 2.7e-07 30.5 12.5 9.2 6.9 0.0 8.5 10 0 0 10 10 7 0 Tetratricopeptide repeat BTAD PF03704.12 KEZ42576.1 - 5.8e-05 23.4 4.7 1.6 9.0 0.0 4.8 3 2 1 5 5 5 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 KEZ42576.1 - 0.00016 21.5 3.1 5.1 7.0 0.0 5.1 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 KEZ42576.1 - 0.00038 19.3 0.3 0.0072 15.1 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.9 KEZ42576.1 - 0.00073 18.8 0.1 0.39 9.8 0.0 2.5 2 0 0 2 2 2 2 Coatomer epsilon subunit MIT PF04212.13 KEZ42576.1 - 0.013 15.3 6.5 1.6 8.6 0.1 3.9 3 2 0 3 3 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 KEZ42576.1 - 0.015 15.2 8.0 3.1 7.8 0.3 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Cutinase PF01083.17 KEZ42577.1 - 5.9e-52 175.9 7.7 8.1e-52 175.5 5.3 1.2 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 KEZ42577.1 - 2.5e-13 49.4 20.6 2.5e-13 49.4 14.3 4.2 5 1 1 6 6 6 1 Fungal cellulose binding domain PE-PPE PF08237.6 KEZ42577.1 - 0.00017 21.1 0.1 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 KEZ42577.1 - 0.0097 15.4 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ42577.1 - 0.025 14.4 0.1 0.037 13.9 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Toxin_7 PF05980.7 KEZ42577.1 - 2.9 8.0 20.4 0.53 10.3 6.5 2.9 2 1 1 3 3 3 0 Toxin 7 EF-hand_6 PF13405.1 KEZ42578.1 - 2.8e-13 48.5 0.1 6.6e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KEZ42578.1 - 6.9e-12 43.7 0.7 2.4e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KEZ42578.1 - 4e-09 36.4 0.0 0.00094 19.2 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KEZ42578.1 - 7.3e-09 34.5 3.4 1.5e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KEZ42578.1 - 2.3e-05 23.9 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 KEZ42578.1 - 0.0066 16.3 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Afi1 PF07792.7 KEZ42580.1 - 7.4e-66 220.6 0.0 1.2e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KEZ42580.1 - 8.2e-37 125.3 0.0 1.5e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KEZ42580.1 - 7.1e-08 31.3 0.1 0.015 13.7 0.0 3.9 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 KEZ42580.1 - 0.056 12.7 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF1168 PF06658.7 KEZ42580.1 - 1.5 8.3 13.3 0.052 13.0 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Esterase PF00756.15 KEZ42581.1 - 1.6e-45 155.5 0.0 1.9e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KEZ42581.1 - 6.7e-07 29.1 0.0 8.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ42581.1 - 0.00018 20.7 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEZ42581.1 - 0.00025 21.0 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KEZ42581.1 - 0.00046 19.5 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.2 KEZ42581.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.20 KEZ42581.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 KEZ42581.1 - 0.099 12.1 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Tyrosinase PF00264.15 KEZ42582.1 - 1.4e-40 139.8 0.0 1.8e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb6 PF01192.17 KEZ42583.1 - 7.8e-25 86.3 0.4 1.3e-24 85.6 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 KEZ42584.1 - 2.5e-33 112.3 55.0 5.8e-05 23.1 0.4 10.8 10 1 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ42584.1 - 1.5e-26 90.7 51.3 0.00041 20.4 0.4 10.6 10 0 0 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ42584.1 - 1.9e-17 62.6 51.6 0.00043 20.4 1.2 10.5 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KEZ42584.1 - 3.3e-11 42.9 27.0 0.076 13.1 0.0 10.0 10 0 0 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ42584.1 - 1.3e-06 28.3 29.3 5.4 7.3 0.1 9.7 10 0 0 10 10 10 4 Zinc-finger of C2H2 type DUF4187 PF13821.1 KEZ42584.1 - 0.0033 16.9 1.2 0.0033 16.9 0.8 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4187) zf-C2HC_2 PF13913.1 KEZ42584.1 - 0.0059 16.2 0.3 0.0059 16.2 0.2 5.0 5 0 0 5 5 5 1 zinc-finger of a C2HC-type Zip PF02535.17 KEZ42585.1 - 1.2e-33 116.5 5.5 1.1e-23 83.8 0.4 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Virul_fac_BrkB PF03631.10 KEZ42585.1 - 8.4 5.6 20.9 0.76 9.0 1.6 2.2 2 0 0 2 2 2 0 Virulence factor BrkB WD40 PF00400.27 KEZ42586.1 - 4.3e-49 162.7 25.5 1e-08 34.7 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KEZ42586.1 - 0.027 14.1 0.0 0.8 9.3 0.0 2.8 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 KEZ42587.1 - 6.8e-21 74.7 19.3 1.3e-20 73.7 13.4 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KEZ42587.1 - 0.0007 19.6 2.6 0.0029 17.6 1.8 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Tmemb_170 PF10190.4 KEZ42588.1 - 0.0022 18.0 9.3 0.0029 17.6 6.4 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Hexapep PF00132.19 KEZ42589.1 - 4.7e-12 44.8 4.7 4.7e-09 35.3 1.8 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEZ42589.1 - 1.7e-11 43.4 5.9 1.3e-08 34.1 1.5 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KEZ42589.1 - 4.5e-11 42.5 0.2 7.3e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase LysM PF01476.15 KEZ42591.1 - 2.3e-08 33.7 0.0 0.00031 20.5 0.0 3.4 3 0 0 3 3 3 3 LysM domain Ubiq_cyt_C_chap PF03981.7 KEZ42592.1 - 8.2e-33 113.2 1.1 2.1e-32 111.9 0.4 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone OPT PF03169.10 KEZ42593.1 - 2.8e-181 604.1 47.6 3.4e-181 603.8 33.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ketoacyl-synt PF00109.21 KEZ42593.1 - 8.6e-56 189.2 4.1 2.2e-55 187.9 0.5 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEZ42593.1 - 3.6e-36 123.5 0.8 6.6e-36 122.7 0.5 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KEZ42593.1 - 0.00034 19.6 0.2 0.00079 18.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEZ42593.1 - 0.012 14.9 0.8 0.032 13.6 0.1 2.0 2 0 0 2 2 2 0 Thiolase, C-terminal domain Dioxygenase_C PF00775.16 KEZ42595.1 - 5.2e-57 192.0 0.0 8.4e-57 191.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEZ42595.1 - 2.8e-14 52.8 0.0 4.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEZ42595.1 - 3.7e-07 30.0 0.0 2.7e-05 24.1 0.0 3.0 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 KEZ42596.1 - 6.6e-10 38.2 0.7 1.1e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ42596.1 - 5.2e-08 32.6 12.7 9.8e-08 31.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF29 PF01724.11 KEZ42596.1 - 0.0029 17.4 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF29 LRR_4 PF12799.2 KEZ42597.1 - 3e-19 68.1 8.4 2e-06 27.2 2.2 4.4 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ42597.1 - 8.2e-14 51.1 7.2 4.8e-09 35.8 2.9 3.0 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KEZ42597.1 - 9.4e-12 43.2 9.6 0.29 11.3 0.2 6.2 5 1 1 6 6 6 5 Leucine Rich Repeat LRR_7 PF13504.1 KEZ42597.1 - 4.2e-06 26.0 10.1 2.9 8.4 0.1 6.3 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 KEZ42597.1 - 0.00025 20.8 8.7 5.7 7.3 0.2 5.7 6 0 0 6 6 6 1 Leucine Rich repeat Hom_end PF05204.9 KEZ42597.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Homing endonuclease Actin PF00022.14 KEZ42598.1 - 3.3e-91 305.6 0.0 1.8e-90 303.2 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEZ42598.1 - 0.15 10.5 0.1 0.36 9.3 0.1 1.9 1 1 0 1 1 1 0 MreB/Mbl protein zf-HC5HC2H_2 PF13832.1 KEZ42599.1 - 3.1e-34 117.2 8.4 3.1e-34 117.2 5.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KEZ42599.1 - 3.9e-26 91.0 8.1 3.9e-26 91.0 5.6 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 KEZ42599.1 - 1.1e-20 74.5 2.7 1.5e-20 74.0 0.0 2.6 3 0 0 3 3 3 1 Enhancer of polycomb-like PHD_2 PF13831.1 KEZ42599.1 - 2.9e-14 52.0 2.1 2.9e-14 52.0 1.4 2.1 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 KEZ42599.1 - 1.2e-09 37.6 22.2 3.7e-08 32.9 6.4 2.8 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 KEZ42599.1 - 1.6 8.7 22.0 0.026 14.4 3.8 2.7 2 0 0 2 2 2 0 RING-like domain Metallophos PF00149.23 KEZ42600.1 - 1.4e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rdx PF10262.4 KEZ42601.1 - 4.8e-27 93.8 0.0 7e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 KEZ42602.1 - 1.2e-26 92.2 0.0 1.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.22 KEZ42603.1 - 8e-09 35.7 0.6 9.9e-08 32.2 0.0 2.6 2 0 0 2 2 2 1 PCI domain Laminin_II PF06009.7 KEZ42604.1 - 1.4e-07 31.3 48.3 0.014 15.1 4.2 4.8 1 1 3 4 4 4 4 Laminin Domain II Fib_alpha PF08702.5 KEZ42604.1 - 3.8e-06 27.0 18.6 0.032 14.3 3.5 4.4 1 1 2 3 3 3 3 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 KEZ42604.1 - 4.8e-06 25.3 31.9 0.00051 18.6 6.1 2.1 1 1 1 2 2 2 2 AAA domain PspA_IM30 PF04012.7 KEZ42604.1 - 4.5e-05 22.9 30.7 0.12 11.7 10.9 3.8 1 1 2 3 3 3 3 PspA/IM30 family MscS_porin PF12795.2 KEZ42604.1 - 5.2e-05 22.6 0.7 0.094 12.0 0.0 3.1 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain Spc7 PF08317.6 KEZ42604.1 - 0.00017 20.3 32.6 0.015 13.9 8.0 3.4 1 1 1 2 2 2 2 Spc7 kinetochore protein Laminin_I PF06008.9 KEZ42604.1 - 0.00026 20.4 34.8 0.084 12.1 7.4 3.7 1 1 3 4 4 4 4 Laminin Domain I MCPsignal PF00015.16 KEZ42604.1 - 0.00029 20.4 54.4 0.00069 19.2 14.1 4.0 1 1 4 5 5 5 3 Methyl-accepting chemotaxis protein (MCP) signalling domain PilJ PF13675.1 KEZ42604.1 - 0.0015 18.8 7.4 3.1 8.1 0.1 3.6 1 1 2 3 3 3 3 Type IV pili methyl-accepting chemotaxis transducer N-term ATG16 PF08614.6 KEZ42604.1 - 0.002 17.9 24.0 0.017 14.9 5.1 3.2 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) SlyX PF04102.7 KEZ42604.1 - 0.0036 17.6 25.3 0.83 10.0 1.1 4.9 1 1 3 4 4 4 2 SlyX DUF4200 PF13863.1 KEZ42604.1 - 0.0079 16.1 12.2 0.022 14.6 1.3 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4200) WXG100 PF06013.7 KEZ42604.1 - 0.034 14.1 8.8 4.4 7.3 0.4 4.0 1 1 1 3 3 3 0 Proteins of 100 residues with WXG AATF-Che1 PF13339.1 KEZ42604.1 - 0.038 14.1 21.5 0.61 10.2 3.4 3.6 1 1 3 4 4 4 0 Apoptosis antagonizing transcription factor TMPIT PF07851.8 KEZ42604.1 - 0.15 11.1 21.9 0.29 10.1 4.8 3.0 1 1 2 3 3 3 0 TMPIT-like protein DUF3552 PF12072.3 KEZ42604.1 - 0.16 11.1 45.8 0.67 9.1 7.5 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF3552) DUF812 PF05667.6 KEZ42604.1 - 0.23 9.9 51.8 1.1 7.6 5.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF812) Reo_sigmaC PF04582.7 KEZ42604.1 - 0.25 10.4 51.8 0.068 12.3 13.1 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Tweety PF04906.8 KEZ42604.1 - 0.26 9.6 24.8 1.2 7.5 1.5 3.8 1 1 2 3 3 3 0 Tweety COG5 PF10392.4 KEZ42604.1 - 0.97 9.3 11.1 0.81 9.6 0.5 3.5 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Ax_dynein_light PF10211.4 KEZ42604.1 - 1.2 8.9 19.2 4.7 6.9 0.5 4.2 1 1 2 4 4 4 0 Axonemal dynein light chain PMEI PF04043.10 KEZ42604.1 - 1.6 8.6 23.7 1.5e+04 -8.7 16.4 4.2 1 1 0 1 1 0 0 Plant invertase/pectin methylesterase inhibitor TMF_DNA_bd PF12329.3 KEZ42604.1 - 1.6 8.5 33.7 4 7.3 4.6 5.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding FH2 PF02181.18 KEZ42604.1 - 1.9 7.3 30.2 11 4.8 6.0 3.1 1 1 0 2 2 2 0 Formin Homology 2 Domain Sulfatase_C PF14707.1 KEZ42604.1 - 2.2 8.5 19.5 31 4.8 1.3 4.8 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase DUF2203 PF09969.4 KEZ42604.1 - 3.1 8.0 29.9 4.3 7.5 4.1 4.1 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) Nsp1_C PF05064.8 KEZ42604.1 - 3.2 7.4 38.9 0.28 10.8 3.7 5.0 1 1 4 5 5 5 0 Nsp1-like C-terminal region DUF4201 PF13870.1 KEZ42604.1 - 8.2 5.8 10.4 5.4 6.4 0.7 3.5 1 1 1 3 3 3 0 Domain of unknown function (DUF4201) IncA PF04156.9 KEZ42604.1 - 8.7 5.8 46.0 16 5.0 6.6 4.1 1 1 2 3 3 3 0 IncA protein DUF745 PF05335.8 KEZ42604.1 - 8.8 5.7 44.3 1.7 8.1 8.6 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF745) Cauli_AT PF03233.8 KEZ42604.1 - 9 5.9 21.7 13 5.4 1.7 3.9 1 1 2 3 3 3 0 Aphid transmission protein Steroid_dh PF02544.11 KEZ42605.1 - 2.3e-13 50.1 2.1 4.3e-13 49.2 1.5 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEZ42605.1 - 0.0088 15.3 0.6 0.0088 15.3 0.4 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) 2OG-FeII_Oxy_2 PF13532.1 KEZ42606.1 - 5.3e-11 42.7 0.0 1.6e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KEZ42606.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 KEZ42607.1 - 2.4e-23 82.2 0.1 1.1e-16 60.9 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ42607.1 - 3.7e-18 64.3 3.4 5.2e-08 32.3 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 KEZ42607.1 - 2.7e-12 45.6 0.1 2.5e-05 24.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KEZ42607.1 - 3.5e-12 46.1 3.5 1.1e-07 31.8 0.2 4.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ42607.1 - 1.8e-11 44.2 0.4 4.4e-08 33.4 0.1 3.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) TGS PF02824.16 KEZ42608.1 - 7.9e-23 80.0 0.1 1.6e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KEZ42608.1 - 3.5e-18 65.6 0.1 1.4e-17 63.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ42608.1 - 4.2e-09 35.8 0.1 2.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KEZ42608.1 - 3.1e-05 23.5 0.2 0.45 9.9 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEZ42608.1 - 0.00016 21.5 0.2 0.038 13.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KEZ42608.1 - 0.0047 15.7 0.4 0.017 13.8 0.1 2.0 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KEZ42608.1 - 0.021 15.3 0.0 0.41 11.1 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein DUF211 PF02680.9 KEZ42608.1 - 0.022 14.5 0.5 0.058 13.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 AAA_28 PF13521.1 KEZ42608.1 - 0.14 12.0 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc5 PF03221.11 KEZ42609.1 - 1e-11 44.4 0.3 2.7e-11 43.1 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KEZ42609.1 - 1.2e-08 34.2 0.0 2.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 KEZ42609.1 - 0.034 13.7 0.1 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain PXA PF02194.10 KEZ42610.1 - 4.1e-41 140.5 0.3 6.5e-41 139.9 0.2 1.3 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KEZ42610.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 Sorting nexin C terminal zf-Mss51 PF13824.1 KEZ42611.1 - 2.7e-28 97.5 5.8 6.2e-28 96.4 4.0 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KEZ42611.1 - 0.018 14.9 0.4 0.035 13.9 0.3 1.5 1 0 0 1 1 1 0 MYND finger CPSF_A PF03178.10 KEZ42612.1 - 1.7e-100 336.2 0.0 7.7e-100 334.0 0.0 2.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 KEZ42612.1 - 5e-68 229.4 0.0 7.8e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 KEZ42612.1 - 0.027 14.3 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat Mtc PF03820.12 KEZ42613.1 - 2.8e-106 354.6 0.1 1.7e-105 352.0 0.0 1.9 1 1 0 1 1 1 1 Tricarboxylate carrier zf-Tim10_DDP PF02953.10 KEZ42613.1 - 1.1e-21 75.8 2.6 1.8e-21 75.2 1.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 KEZ42613.1 - 0.058 13.2 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) DUF4045 PF13254.1 KEZ42614.1 - 4.6e-55 187.6 26.9 5.4e-37 128.0 3.5 8.1 6 2 1 7 7 7 3 Domain of unknown function (DUF4045) Gelsolin PF00626.17 KEZ42614.1 - 9.7e-09 34.8 0.0 0.0054 16.3 0.0 3.7 3 1 0 3 3 3 2 Gelsolin repeat SepQ PF06622.6 KEZ42614.1 - 0.81 8.5 0.0 1.3 7.8 0.0 1.1 1 0 0 1 1 1 0 SepQ protein DUF2347 PF09804.4 KEZ42615.1 - 4.8e-88 295.0 0.0 9.5e-86 287.5 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KEZ42615.1 - 4.3e-37 127.9 0.0 8e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KEZ42615.1 - 0.00035 20.2 0.0 0.0032 17.1 0.0 2.1 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KEZ42615.1 - 0.16 10.4 0.0 9.2 4.6 0.0 2.6 3 0 0 3 3 3 0 Transport protein Avl9 Sec63 PF02889.11 KEZ42616.1 - 1.3e-46 159.3 0.0 7.7e-46 156.7 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KEZ42616.1 - 3e-18 65.3 0.8 7.4e-18 64.0 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain DUF605 PF04652.11 KEZ42617.1 - 1.7 7.9 17.8 2.1 7.6 12.4 1.1 1 0 0 1 1 1 0 Vta1 like Acyltransferase PF01553.16 KEZ42618.1 - 2.7e-34 117.4 0.0 4.1e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 KEZ42618.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP ATP-synt_DE_N PF02823.11 KEZ42619.1 - 6.5e-20 70.6 0.3 8.8e-20 70.2 0.2 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF3567 PF12091.3 KEZ42619.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Arf PF00025.16 KEZ42620.1 - 1.6e-66 222.8 0.0 1.8e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEZ42620.1 - 8.1e-11 41.2 0.1 3.8e-07 29.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KEZ42620.1 - 4.5e-08 33.6 0.0 6.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KEZ42620.1 - 1.9e-07 30.6 0.0 2.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KEZ42620.1 - 2e-07 30.4 0.0 2.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KEZ42620.1 - 2.6e-07 30.6 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KEZ42620.1 - 6.4e-06 25.4 0.0 6.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEZ42620.1 - 0.00048 19.6 0.0 0.024 14.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 KEZ42620.1 - 0.099 12.3 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KEZ42620.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF3336 PF11815.3 KEZ42621.1 - 7.4e-49 164.9 4.9 1.2e-48 164.3 3.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEZ42621.1 - 1.4e-21 77.3 0.5 3.4e-21 76.1 0.1 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase Cytochrom_C_2 PF01322.15 KEZ42621.1 - 0.13 12.8 0.4 1.2 9.7 0.2 2.1 2 0 0 2 2 2 0 Cytochrome C' Pkinase PF00069.20 KEZ42622.1 - 4.5e-71 239.0 0.0 5.5e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42622.1 - 9.8e-38 129.6 0.0 1.4e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42622.1 - 5.5e-08 32.1 0.0 8.9e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAT1 PF09770.4 KEZ42622.1 - 2.2 6.4 26.1 2.6 6.1 18.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lectin_leg-like PF03388.8 KEZ42623.1 - 6.7e-67 224.9 0.0 8.9e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KEZ42623.1 - 0.0051 16.2 0.0 2.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain Methyltransf_FA PF12248.3 KEZ42623.1 - 0.014 15.4 0.0 0.045 13.7 0.0 1.8 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase PBP1_TM PF14812.1 KEZ42623.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 KEZ42624.1 - 6e-59 199.3 0.0 8.5e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42624.1 - 2.8e-19 69.2 0.0 2.3e-18 66.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KEZ42624.1 - 0.032 13.6 0.0 0.76 9.0 0.0 2.5 2 1 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 KEZ42624.1 - 0.085 11.6 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro_3 PF00933.16 KEZ42625.1 - 3.5e-90 302.0 0.0 4.9e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ42625.1 - 7.3e-58 195.7 0.2 5.2e-57 192.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ42625.1 - 4.8e-18 64.8 0.1 9e-18 63.9 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Trypan_PARP PF05887.6 KEZ42625.1 - 0.31 10.8 16.7 0.66 9.7 11.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ERG4_ERG24 PF01222.12 KEZ42626.1 - 4.8e-160 532.8 5.3 5.9e-160 532.5 3.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KEZ42626.1 - 0.0084 15.4 0.2 0.0084 15.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 KEZ42627.1 - 4.9e-11 42.1 0.0 7.3e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 KEZ42627.1 - 7.3e-08 32.3 0.5 9.2e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KEZ42627.1 - 2.7e-07 30.1 11.8 0.0011 18.3 2.7 3.3 1 1 2 3 3 3 2 Autophagy-related protein 27 PBP1_TM PF14812.1 KEZ42627.1 - 6.8 7.0 17.4 0.16 12.2 5.0 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PDEase_II PF02112.10 KEZ42628.1 - 1.5e-52 178.5 0.0 2.8e-22 79.1 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.22 KEZ42628.1 - 0.0017 18.0 0.2 0.0047 16.5 0.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEZ42628.1 - 0.011 15.2 0.0 0.041 13.4 0.0 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Flavin_Reduct PF01613.13 KEZ42629.1 - 2.3e-20 73.0 0.5 3.7e-20 72.3 0.0 1.4 2 0 0 2 2 2 1 Flavin reductase like domain DUF447 PF04289.7 KEZ42629.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Med22 PF06179.7 KEZ42631.1 - 3.1e-07 30.3 0.2 3.5e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF11 PF01345.13 KEZ42632.1 - 0.085 12.9 2.7 0.1 12.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF11 Pkinase PF00069.20 KEZ42633.1 - 1.3e-53 181.8 0.0 1.5e-47 161.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42633.1 - 2.5e-22 79.2 0.0 4.4e-21 75.1 0.0 2.3 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42633.1 - 0.00032 19.7 0.0 0.0012 17.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like AUX_IAA PF02309.11 KEZ42633.1 - 0.0045 16.7 2.4 0.0069 16.1 1.7 1.3 1 0 0 1 1 1 1 AUX/IAA family APH PF01636.18 KEZ42633.1 - 0.011 15.4 2.0 0.057 13.1 1.3 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Lung_7-TM_R PF06814.8 KEZ42634.1 - 2.9e-70 236.5 18.8 3.7e-70 236.2 13.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 KEZ42634.1 - 0.03 14.4 23.9 0.12 12.5 3.1 3.7 1 1 1 3 3 3 0 PrgI family protein DUF1980 PF09323.5 KEZ42634.1 - 0.15 11.7 1.7 0.56 9.9 1.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4131 PF13567.1 KEZ42634.1 - 0.23 10.8 13.5 0.035 13.5 1.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_28 PF02636.12 KEZ42635.1 - 1.7e-76 256.9 0.0 2.6e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pro_isomerase PF00160.16 KEZ42636.1 - 1e-50 171.9 0.1 1.7e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KEZ42636.1 - 7.3e-06 25.8 0.0 4.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 U-box domain APH PF01636.18 KEZ42638.1 - 2.5e-08 33.9 0.4 4.2e-08 33.2 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_60s PF00428.14 KEZ42639.1 - 0.43 10.9 3.8 1 9.7 2.6 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF1762 PF08574.5 KEZ42640.1 - 1.8e-09 37.8 6.3 1.8e-09 37.8 4.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) Pneumo_att_G PF05539.6 KEZ42641.1 - 0.89 8.8 2.9 1.1 8.5 2.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G His_Phos_1 PF00300.17 KEZ42642.1 - 2.1e-23 83.1 0.0 2.9e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SIN1 PF05422.7 KEZ42643.1 - 7e-39 133.7 0.1 1.7e-18 66.4 0.0 2.9 3 0 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KEZ42643.1 - 0.0066 16.3 0.1 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG TrbC PF04956.8 KEZ42644.1 - 0.97 9.4 6.3 0.22 11.5 1.0 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family Zip PF02535.17 KEZ42645.1 - 2.2e-40 138.6 12.5 1.5e-38 132.6 8.7 3.0 1 1 0 1 1 1 1 ZIP Zinc transporter Trypan_PARP PF05887.6 KEZ42645.1 - 0.031 14.0 3.2 0.64 9.8 3.1 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF805 PF05656.9 KEZ42645.1 - 0.19 11.5 0.0 0.19 11.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF805) WD40 PF00400.27 KEZ42646.1 - 1.4e-51 170.5 17.3 5.2e-10 38.8 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KEZ42646.1 - 9.2e-13 47.7 0.9 2e-12 46.6 0.6 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KEZ42646.1 - 2.6e-08 32.4 12.8 0.0097 14.0 2.3 5.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KEZ42646.1 - 3.5e-06 26.5 2.4 7.9e-06 25.3 1.7 1.7 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 KEZ42646.1 - 0.0091 16.2 3.1 30 5.0 0.0 5.1 5 0 0 5 5 5 0 PQQ-like domain E1_dh PF00676.15 KEZ42647.1 - 3.3e-115 383.9 0.1 4e-115 383.6 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KEZ42647.1 - 0.0043 16.0 0.0 0.008 15.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.16 KEZ42648.1 - 1e-57 194.7 0.4 2e-46 157.9 0.1 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEZ42648.1 - 3.4e-52 176.8 0.1 8e-52 175.6 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEZ42648.1 - 1.1e-27 96.2 0.0 4.5e-27 94.2 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 KEZ42648.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain DNA_ligase_OB_2 PF14743.1 KEZ42648.1 - 0.12 12.0 0.2 17 5.1 0.1 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Voltage_CLC PF00654.15 KEZ42649.1 - 8.4e-90 301.3 29.1 8.4e-90 301.3 20.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel Neurochondrin PF05536.6 KEZ42650.1 - 1.1e-64 218.7 0.0 4.1e-33 114.5 0.0 2.1 1 1 1 2 2 2 2 Neurochondrin V-ATPase_H_N PF03224.9 KEZ42650.1 - 6e-05 22.3 0.0 0.00043 19.5 0.0 2.2 2 1 1 3 3 3 1 V-ATPase subunit H RIX1 PF08167.7 KEZ42650.1 - 0.0042 16.7 0.1 0.013 15.1 0.1 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Ras PF00071.17 KEZ42651.1 - 9.2e-52 174.6 0.0 1.1e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ42651.1 - 3.9e-15 56.3 0.0 7.6e-15 55.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEZ42651.1 - 9.8e-06 24.9 0.0 1.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family tRNA-synt_2 PF00152.15 KEZ42652.1 - 3.8e-71 239.5 0.0 5.6e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEZ42652.1 - 3.5e-08 33.1 0.0 6.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain His_Phos_2 PF00328.17 KEZ42653.1 - 3e-23 82.7 0.0 4.6e-22 78.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 KEZ42653.1 - 0.018 15.1 0.0 0.047 13.7 0.0 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) MreB_Mbl PF06723.8 KEZ42654.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein 7TM_GPCR_Srw PF10324.4 KEZ42655.1 - 0.021 13.9 1.6 0.034 13.2 1.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw CRPA PF05745.6 KEZ42655.1 - 0.03 14.1 1.0 0.066 13.0 0.7 1.6 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF2721 PF11026.3 KEZ42655.1 - 7.7 6.1 9.9 0.75 9.4 2.6 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Gtr1_RagA PF04670.7 KEZ42656.1 - 2.8e-66 223.0 0.1 3.3e-66 222.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEZ42656.1 - 0.00021 21.7 0.0 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEZ42656.1 - 0.015 14.5 0.1 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Apc4 PF12896.2 KEZ42657.1 - 1.9e-54 184.1 0.3 2.7e-54 183.6 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 KEZ42657.1 - 0.00031 20.5 0.0 0.0013 18.5 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat Adap_comp_sub PF00928.16 KEZ42658.1 - 2.4e-17 62.9 0.1 3.3e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEZ42658.1 - 2.5e-07 30.5 0.1 5.5e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF2420 PF10336.4 KEZ42659.1 - 0.0022 17.5 1.5 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.9 KEZ42660.1 - 1.7e-103 345.6 13.4 2.2e-103 345.3 9.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KEZ42660.1 - 2.9e-08 33.9 1.8 2.9e-08 33.9 1.2 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KEZ42660.1 - 5.1e-05 23.3 6.1 5.1e-05 23.3 4.3 3.0 3 1 0 3 3 3 2 EamA-like transporter family Ribosomal_S3_C PF00189.15 KEZ42661.1 - 4.4e-16 58.8 0.0 9.7e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KEZ42661.1 - 2.6e-12 46.1 0.1 4.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KEZ42661.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 KEZ42662.1 - 1e-126 422.4 0.0 1.3e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 KEZ42662.1 - 0.023 14.9 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KEZ42662.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase B3_4 PF03483.12 KEZ42663.1 - 4e-25 88.2 0.1 7.4e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KEZ42663.1 - 5.5e-15 54.9 0.0 1.6e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.17 KEZ42664.1 - 2.2e-42 139.3 17.6 0.0029 17.5 0.1 13.1 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 KEZ42664.1 - 1.7e-30 105.1 1.5 1.2e-07 31.8 0.0 7.4 3 3 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KEZ42664.1 - 1.2e-10 41.5 2.2 0.014 15.7 0.1 7.0 5 2 4 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KEZ42664.1 - 2.1e-09 37.5 9.9 0.054 13.9 0.0 8.6 8 1 2 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KEZ42664.1 - 2.5e-07 29.3 6.7 0.0019 16.6 0.7 5.1 4 1 2 6 6 6 3 Adaptin N terminal region DUF2435 PF10363.4 KEZ42664.1 - 6e-05 22.8 2.9 0.057 13.3 0.2 4.4 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 KEZ42664.1 - 0.00025 20.4 2.4 0.74 9.1 0.0 4.7 4 2 2 6 6 6 1 CLASP N terminal Cnd3 PF12719.2 KEZ42664.1 - 0.0043 16.0 0.2 0.03 13.2 0.1 2.3 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 KEZ42664.1 - 0.028 14.2 4.4 1.9 8.4 0.0 4.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KEZ42664.1 - 0.062 13.1 7.3 0.92 9.3 0.1 5.0 5 2 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Ecm29 PF13001.2 KEZ42664.1 - 0.093 11.1 0.4 4.8 5.5 0.0 2.7 3 0 0 3 3 3 0 Proteasome stabiliser Proteasom_PSMB PF10508.4 KEZ42664.1 - 0.1 10.8 2.5 1 7.5 0.0 2.8 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Trp_Tyr_perm PF03222.8 KEZ42664.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.4 1 1 0 1 1 1 0 Tryptophan/tyrosine permease family Methyltransf_18 PF12847.2 KEZ42665.1 - 2e-17 63.7 0.0 3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42665.1 - 1.1e-11 44.5 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ42665.1 - 7.9e-08 32.1 0.0 5.1e-07 29.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42665.1 - 3.1e-07 30.7 0.0 1.2e-06 28.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ42665.1 - 5e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42665.1 - 2.6e-05 24.6 0.0 6.2e-05 23.4 0.0 1.8 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ42665.1 - 3.3e-05 24.1 0.0 5.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KEZ42665.1 - 0.0005 20.1 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 KEZ42665.1 - 0.0047 16.3 0.0 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KEZ42665.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KEZ42665.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ42665.1 - 0.066 12.2 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase RR_TM4-6 PF06459.7 KEZ42666.1 - 2.7 7.8 21.2 0.21 11.4 7.4 2.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RCC1 PF00415.13 KEZ42667.1 - 6.3e-51 170.3 2.8 1.2e-08 35.0 0.4 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEZ42667.1 - 5e-37 124.7 15.6 2.4e-08 33.3 0.0 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.10 KEZ42667.1 - 0.00029 20.4 0.4 1.2 9.0 0.0 3.6 4 0 0 4 4 4 2 Kelch motif RCC1 PF00415.13 KEZ42668.1 - 8.3e-47 157.1 16.6 1.5e-08 34.7 0.1 8.8 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEZ42668.1 - 3.3e-26 90.2 33.9 3.1e-08 33.0 0.8 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Nop14 PF04147.7 KEZ42668.1 - 0.11 10.4 36.5 0.19 9.6 25.3 1.3 1 0 0 1 1 1 0 Nop14-like family CBM_X PF06204.6 KEZ42668.1 - 1.4 8.4 4.6 59 3.2 0.3 3.8 3 0 0 3 3 3 0 Putative carbohydrate binding domain CDC45 PF02724.9 KEZ42668.1 - 8.6 4.2 25.5 15 3.5 17.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Pro-kuma_activ PF09286.6 KEZ42669.1 - 4.7e-36 123.9 0.0 1.1e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KEZ42669.1 - 9.5e-07 28.2 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family ABC_membrane PF00664.18 KEZ42670.1 - 2e-85 286.5 25.3 4.1e-47 160.8 3.3 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ42670.1 - 4.8e-52 175.8 0.0 1.2e-30 106.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ42670.1 - 6.8e-11 41.8 1.2 0.0025 17.1 0.0 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KEZ42670.1 - 4.3e-05 23.0 0.1 0.043 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KEZ42670.1 - 6e-05 22.9 0.2 0.4 10.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KEZ42670.1 - 0.00022 21.6 0.1 1.1 9.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 KEZ42670.1 - 0.00023 21.5 0.1 0.062 13.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KEZ42670.1 - 0.0004 19.5 0.3 0.091 11.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KEZ42670.1 - 0.00048 20.1 0.4 2.3 8.0 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 KEZ42670.1 - 0.0013 18.1 0.2 1.8 8.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ42670.1 - 0.0035 17.3 0.4 1.9 8.4 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 KEZ42670.1 - 0.0051 16.6 2.2 0.46 10.2 0.1 2.6 2 0 0 2 2 2 1 Dynamin family ABC_membrane_2 PF06472.10 KEZ42670.1 - 0.0061 15.7 0.1 0.0061 15.7 0.1 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 FtsK_SpoIIIE PF01580.13 KEZ42670.1 - 0.01 15.3 0.4 3.5 7.0 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KEZ42670.1 - 0.011 15.8 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 KEZ42670.1 - 0.017 14.9 0.8 0.72 9.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 KEZ42670.1 - 0.047 13.2 4.1 2.1 7.9 0.0 3.5 3 1 0 3 3 3 0 AAA domain NACHT PF05729.7 KEZ42670.1 - 0.21 11.2 1.3 0.53 9.9 0.1 2.2 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 KEZ42670.1 - 0.24 10.8 2.4 0.68 9.3 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2841 PF11001.3 KEZ42671.1 - 4.6e-40 136.3 4.5 7.6e-40 135.6 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF155 PF02582.9 KEZ42672.1 - 4.7e-56 189.4 0.1 6.2e-56 189.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.14 KEZ42673.1 - 6.2e-12 45.6 4.7 6.2e-12 45.6 3.3 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEZ42673.1 - 3e-06 27.5 5.9 3e-06 27.5 4.1 3.0 4 0 0 4 4 4 1 HMG-box domain Atg14 PF10186.4 KEZ42673.1 - 0.83 8.5 13.7 0.084 11.8 1.8 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Saccharop_dh PF03435.13 KEZ42674.1 - 1.4e-17 63.7 0.1 3.2e-17 62.6 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KEZ42674.1 - 0.00063 20.0 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEZ42674.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 KEZ42674.1 - 0.037 14.1 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KEZ42674.1 - 0.07 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 KEZ42674.1 - 0.078 12.9 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cpn60_TCP1 PF00118.19 KEZ42675.1 - 2.2e-138 461.9 3.7 2.5e-138 461.7 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 KEZ42675.1 - 0.056 13.5 0.0 0.25 11.4 0.0 2.1 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor PHD PF00628.24 KEZ42676.1 - 1.2e-11 44.0 11.9 2.5e-10 39.8 3.4 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING_2 PF13639.1 KEZ42676.1 - 4.3e-09 36.0 16.4 1.2e-08 34.6 0.3 3.8 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KEZ42676.1 - 7.8e-08 32.3 10.0 1.6e-06 28.1 1.0 3.0 2 1 0 2 2 2 2 RING-H2 zinc finger PHD_2 PF13831.1 KEZ42676.1 - 2e-05 23.8 2.4 2e-05 23.8 1.7 2.2 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.1 KEZ42676.1 - 2.4e-05 23.9 6.1 0.00017 21.2 0.3 3.5 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEZ42676.1 - 0.00015 21.3 0.5 0.00015 21.3 0.3 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KEZ42676.1 - 0.00019 20.9 3.6 0.0014 18.1 0.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 KEZ42676.1 - 0.00043 19.8 2.7 0.00043 19.8 1.9 3.2 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEZ42676.1 - 0.00092 18.9 4.2 0.026 14.3 0.2 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KEZ42676.1 - 0.001 19.0 0.7 0.001 19.0 0.5 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-PHD-like PF15446.1 KEZ42676.1 - 0.0055 16.0 1.0 0.0055 16.0 0.7 2.4 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 KEZ42676.1 - 0.021 14.5 9.6 0.064 13.0 4.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-P11 PF03854.9 KEZ42676.1 - 0.48 9.9 3.5 0.48 9.9 0.3 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_6 PF14835.1 KEZ42676.1 - 5.3 6.9 7.7 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein AAA PF00004.24 KEZ42677.1 - 1.8e-24 86.4 0.0 3.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KEZ42677.1 - 2.6e-10 40.0 0.0 2.5e-09 36.8 0.0 2.6 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.8 KEZ42677.1 - 4.4e-07 29.0 0.0 7.5e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEZ42677.1 - 1.3e-05 25.9 0.0 5.2e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ42677.1 - 1.8e-05 24.8 0.0 0.00011 22.2 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KEZ42677.1 - 7.7e-05 22.9 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEZ42677.1 - 0.00014 21.9 0.0 0.00055 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ42677.1 - 0.00015 21.5 0.0 0.00048 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KEZ42677.1 - 0.00086 19.4 0.0 0.0027 17.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 KEZ42677.1 - 0.0012 18.2 0.1 0.019 14.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KEZ42677.1 - 0.0047 16.8 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEZ42677.1 - 0.0064 16.4 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ42677.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KEZ42677.1 - 0.01 15.5 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein RuvB_N PF05496.7 KEZ42677.1 - 0.021 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 KEZ42677.1 - 0.031 13.1 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 KEZ42677.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 KEZ42677.1 - 0.055 13.2 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 1 0 Part of AAA domain IstB_IS21 PF01695.12 KEZ42677.1 - 0.093 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KEZ42677.1 - 0.1 12.1 0.3 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEZ42677.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KEZ42677.1 - 0.13 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 KEZ42677.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus CPT PF07931.7 KEZ42677.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 KEZ42677.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MRP-L46 PF11788.3 KEZ42678.1 - 2.7e-30 105.2 0.2 4.8e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KEZ42678.1 - 0.00067 19.3 0.1 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 KEZ42679.1 - 4.7e-30 104.7 0.0 2.7e-29 102.2 0.0 1.9 1 1 0 1 1 1 1 CAF1 family ribonuclease Acetyltransf_4 PF13420.1 KEZ42679.1 - 0.0059 16.5 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lip_A_acyltrans PF03279.8 KEZ42679.1 - 0.11 11.3 0.1 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase SMC_N PF02463.14 KEZ42680.1 - 2.3e-58 197.0 30.7 2e-57 193.9 21.3 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEZ42680.1 - 1.6e-27 95.8 0.6 1.2e-26 93.0 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KEZ42680.1 - 7.8e-17 62.1 0.0 7.4e-08 32.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEZ42680.1 - 4.4e-12 46.7 26.0 4.4e-12 46.7 18.0 6.6 2 2 1 4 4 3 1 AAA domain AAA_15 PF13175.1 KEZ42680.1 - 7.4e-11 41.7 12.9 3.7e-07 29.5 2.8 3.1 3 1 0 3 3 3 2 AAA ATPase domain GAS PF13851.1 KEZ42680.1 - 0.00035 19.8 1.4 0.00035 19.8 1.0 6.8 3 2 2 6 6 6 1 Growth-arrest specific micro-tubule binding AAA_29 PF13555.1 KEZ42680.1 - 0.00044 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.4 KEZ42680.1 - 0.0011 18.7 3.3 0.0011 18.7 2.3 7.4 2 2 3 6 6 6 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 KEZ42680.1 - 0.091 11.2 76.2 0.078 11.4 7.4 5.9 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.22 KEZ42680.1 - 0.3 11.3 0.0 0.3 11.3 0.0 6.1 3 2 0 3 3 2 0 ABC transporter Reo_sigmaC PF04582.7 KEZ42680.1 - 0.59 9.2 14.1 0.081 12.0 0.5 4.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein DUF3535 PF12054.3 KEZ42681.1 - 1.9e-140 468.4 0.1 1.3e-139 465.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KEZ42681.1 - 2.4e-74 249.8 0.0 3.6e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KEZ42681.1 - 2.2e-17 61.4 9.0 0.0031 17.4 0.0 9.2 10 0 0 10 10 10 6 HEAT repeat Helicase_C PF00271.26 KEZ42681.1 - 4.2e-14 52.1 0.0 1.2e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 KEZ42681.1 - 3.2e-08 33.7 10.5 0.00078 19.6 0.0 7.6 7 2 1 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.2 KEZ42681.1 - 2.5e-05 24.5 4.0 0.74 10.2 0.0 4.1 4 0 0 4 4 4 3 Vacuolar 14 Fab1-binding region CDC37_N PF03234.9 KEZ42682.1 - 4.5e-55 186.7 5.7 4.5e-55 186.7 3.9 2.9 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KEZ42682.1 - 9e-43 145.7 3.2 1.1e-42 145.4 1.5 1.7 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KEZ42682.1 - 2.6e-24 84.9 0.6 2.6e-24 84.9 0.4 3.0 3 0 0 3 3 3 1 Cdc37 C terminal domain ING PF12998.2 KEZ42682.1 - 0.034 14.4 0.9 0.034 14.4 0.6 2.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Phage_GPO PF05929.6 KEZ42682.1 - 0.075 12.2 4.7 0.048 12.9 1.4 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4482 PF14818.1 KEZ42682.1 - 0.38 11.4 11.0 12 6.5 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) SPX PF03105.14 KEZ42682.1 - 0.39 10.4 12.2 0.45 10.2 7.9 1.5 1 1 0 1 1 1 0 SPX domain APG17 PF04108.7 KEZ42683.1 - 1.1e-96 324.1 3.4 1.3e-96 323.9 2.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 EzrA PF06160.7 KEZ42683.1 - 0.014 13.5 4.4 0.014 13.6 2.1 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA IncA PF04156.9 KEZ42683.1 - 0.038 13.6 10.7 3.1 7.3 5.7 3.4 2 1 0 2 2 2 0 IncA protein ATG19_autophagy PF12744.2 KEZ42683.1 - 0.085 12.0 0.2 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Glyco_hydro_45 PF02015.11 KEZ42684.1 - 5.2e-39 134.3 7.2 6.2e-39 134.1 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 2OG-FeII_Oxy PF03171.15 KEZ42685.1 - 0.00011 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KEZ42685.1 - 0.002 18.6 0.0 0.0031 18.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.27 KEZ42686.1 - 1.3e-61 202.4 18.3 1.1e-10 40.8 0.1 8.4 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KEZ42686.1 - 2.3e-14 52.8 0.7 4.1e-14 52.0 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ42686.1 - 4.8e-11 42.0 0.3 1.1e-10 40.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KEZ42686.1 - 9e-08 30.6 4.5 0.15 10.1 0.0 4.9 3 2 1 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KEZ42686.1 - 0.0002 21.1 0.6 1.5 8.6 0.1 3.7 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 KEZ42686.1 - 0.013 14.3 0.2 3.5 6.2 0.0 2.8 2 1 0 3 3 3 0 Nup133 N terminal like PRANC PF09372.5 KEZ42686.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 PRANC domain YmzC PF14157.1 KEZ42686.1 - 0.56 10.0 3.1 5 7.0 0.0 3.8 5 0 0 5 5 5 0 YmzC-like protein Zip PF02535.17 KEZ42686.1 - 5 6.0 9.7 1.1 8.1 3.9 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Mito_carr PF00153.22 KEZ42687.1 - 1.8e-70 232.7 2.3 1.8e-22 78.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 KEZ42688.1 - 5.7e-22 77.9 0.0 3.4e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WHIM3 PF15614.1 KEZ42688.1 - 0.038 13.7 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 RNase_T PF00929.19 KEZ42689.1 - 3.5e-08 33.8 0.0 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 2 Exonuclease RdRP PF05183.7 KEZ42690.1 - 2.7e-129 432.5 0.1 3.7e-129 432.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fungal_trans PF04082.13 KEZ42691.1 - 5.3e-07 28.7 0.0 1.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 KEZ42692.1 - 2.1e-137 442.6 50.3 1.1e-14 53.6 0.3 10.6 10 0 0 10 10 10 10 WD domain, G-beta repeat eIF2A PF08662.6 KEZ42692.1 - 5.8e-23 81.6 7.4 3e-08 33.5 0.1 4.7 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KEZ42692.1 - 1.4e-12 46.5 19.2 0.2 9.7 0.1 8.8 1 1 7 8 8 8 7 Nucleoporin Nup120/160 NACHT PF05729.7 KEZ42692.1 - 1.6e-11 44.1 0.0 3.9e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 KEZ42692.1 - 6.2e-06 24.7 1.1 0.036 12.3 0.0 3.7 1 1 2 4 4 4 2 Cytochrome D1 heme domain CDtoxinA PF03498.9 KEZ42692.1 - 1.3e-05 24.5 3.8 15 4.9 0.1 6.4 1 1 8 9 9 9 0 Cytolethal distending toxin A/C family CNH PF00780.17 KEZ42692.1 - 5.2e-05 22.7 0.8 31 3.8 0.0 6.6 3 2 5 8 8 8 0 CNH domain APS_kinase PF01583.15 KEZ42692.1 - 0.02 14.5 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 KEZ42692.1 - 0.075 12.0 2.0 0.11 11.4 0.5 1.7 1 1 1 2 2 2 0 KAP family P-loop domain AAA_22 PF13401.1 KEZ42692.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEZ42692.1 - 0.17 12.0 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C2 PF00648.16 KEZ42693.1 - 2.8e-49 167.7 5.6 1.8e-35 122.3 0.3 3.1 3 0 0 3 3 3 2 Calpain family cysteine protease NicO PF03824.11 KEZ42694.1 - 1.8e-57 194.8 9.7 2.3e-57 194.4 6.7 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein YjbE PF11106.3 KEZ42694.1 - 0.075 13.0 0.3 0.075 13.0 0.2 2.4 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Sulfotransfer_3 PF13469.1 KEZ42695.1 - 0.0009 20.2 4.9 0.002 19.0 3.3 1.7 1 1 0 1 1 1 1 Sulfotransferase family DUF2976 PF11190.3 KEZ42696.1 - 5.6 6.5 7.6 0.57 9.7 1.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) Glyco_hydro_7 PF00840.15 KEZ42697.1 - 4.7e-143 476.6 8.6 5.8e-143 476.3 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DEC-1_N PF04625.8 KEZ42697.1 - 5.8 5.4 6.4 8.9 4.8 4.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region EBP PF05241.7 KEZ42698.1 - 7.7e-08 31.5 3.7 1.1e-07 31.0 2.6 1.2 1 1 0 1 1 1 1 Emopamil binding protein DUF3439 PF11921.3 KEZ42698.1 - 4.5 7.0 9.1 7.3 6.3 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TraG_N PF07916.6 KEZ42699.1 - 0.087 11.2 0.1 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Dynactin_p62 PF05502.8 KEZ42700.1 - 5.5e-155 516.8 0.0 6.9e-155 516.4 0.0 1.2 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 KEZ42700.1 - 0.14 12.0 0.4 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_S7e PF01251.13 KEZ42701.1 - 2.9e-83 278.0 0.7 3.2e-83 277.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e RCC1 PF00415.13 KEZ42702.1 - 8.6e-51 169.9 6.5 4e-08 33.3 0.0 8.3 7 3 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEZ42702.1 - 3.3e-31 106.1 29.2 5.7e-07 28.9 0.4 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Choline_transpo PF04515.7 KEZ42703.1 - 1.8e-101 339.2 25.4 1.8e-101 339.2 17.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter OPT PF03169.10 KEZ42704.1 - 2.3e-176 587.9 48.3 2.6e-176 587.7 33.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.11 KEZ42705.1 - 4.3e-38 130.9 32.5 4.3e-38 130.9 22.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MAPEG PF01124.13 KEZ42706.1 - 2.9e-18 65.6 2.1 3.4e-18 65.4 1.4 1.0 1 0 0 1 1 1 1 MAPEG family DEAD PF00270.24 KEZ42708.1 - 2.5e-42 144.2 0.1 4.8e-42 143.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2183 PF09949.4 KEZ42708.1 - 6.4e-32 109.4 0.0 1.6e-31 108.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.26 KEZ42708.1 - 4.7e-24 84.0 0.0 1.1e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LNS2 PF08235.8 KEZ42708.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF1253 PF06862.7 KEZ42708.1 - 0.022 13.1 0.0 0.1 10.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1253) CH PF00307.26 KEZ42709.1 - 0.00024 21.0 0.1 0.0003 20.8 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain F-box-like PF12937.2 KEZ42710.1 - 1.4e-06 27.9 0.2 3.6e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Velvet PF11754.3 KEZ42711.1 - 1.2e-06 28.3 0.0 1.5e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Velvet factor Peptidase_S8 PF00082.17 KEZ42712.1 - 2.3e-54 184.4 0.0 5.6e-54 183.2 0.0 1.6 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 KEZ42712.1 - 8.7e-11 41.4 0.0 3.2e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 KEZ42712.1 - 1.7e-08 34.8 0.0 5.2e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) ACC_central PF08326.7 KEZ42713.1 - 9.1e-239 794.2 0.0 1.1e-238 793.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KEZ42713.1 - 4.8e-175 582.6 0.0 6.4e-175 582.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KEZ42713.1 - 2.9e-52 177.0 0.0 5.4e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KEZ42713.1 - 8.1e-24 83.8 0.1 1.6e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEZ42713.1 - 2.5e-22 78.8 0.0 3.5e-20 71.9 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KEZ42713.1 - 5.4e-16 58.0 0.2 1.4e-15 56.7 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KEZ42713.1 - 1.2e-09 38.2 0.0 2.9e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEZ42713.1 - 9.3e-08 31.1 0.0 0.002 16.9 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KEZ42713.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KEZ42713.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KEZ42713.1 - 0.012 15.2 0.0 0.056 13.1 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like ATP-grasp PF02222.17 KEZ42713.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain NUDE_C PF04880.8 KEZ42714.1 - 5.5e-21 75.6 9.7 5.5e-21 75.6 6.7 4.9 2 1 3 5 5 3 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 KEZ42714.1 - 0.0009 19.4 7.7 0.0009 19.4 5.3 3.8 3 1 0 3 3 2 1 Protein of unknown function (DUF904) DUF869 PF05911.6 KEZ42714.1 - 0.012 13.9 17.0 0.025 12.8 11.8 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) WEMBL PF05701.6 KEZ42714.1 - 0.028 12.8 28.1 0.044 12.2 19.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light IncA PF04156.9 KEZ42714.1 - 0.075 12.6 36.2 0.41 10.2 8.5 2.8 2 1 1 3 3 3 0 IncA protein ADIP PF11559.3 KEZ42714.1 - 0.41 10.5 31.5 1.5 8.7 6.4 4.0 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 KEZ42714.1 - 0.51 10.1 37.3 1.6 8.5 16.7 3.6 2 1 1 3 3 3 0 Tropomyosin like Filament PF00038.16 KEZ42714.1 - 0.66 9.3 30.8 3.1 7.1 5.5 2.9 2 1 1 3 3 3 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 KEZ42714.1 - 1 9.1 37.9 0.64 9.8 5.4 3.6 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Chibby PF14645.1 KEZ42714.1 - 1.5 8.6 12.1 0.02 14.7 1.8 2.6 2 1 1 3 3 3 0 Chibby family AKNA PF12443.3 KEZ42714.1 - 1.6 8.8 11.1 2.2 8.3 0.6 3.8 3 1 0 3 3 3 0 AT-hook-containing transcription factor EAP30 PF04157.11 KEZ42714.1 - 1.6 7.8 17.3 1.2 8.2 2.4 3.5 3 1 1 4 4 4 0 EAP30/Vps36 family ATG16 PF08614.6 KEZ42714.1 - 1.8 8.3 31.7 2 8.1 11.0 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KEZ42714.1 - 4.3 5.6 20.3 31 2.8 14.6 1.9 2 1 0 2 2 2 0 AAA domain Tho2 PF11262.3 KEZ42714.1 - 4.4 6.2 10.5 4.1 6.3 0.5 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Prefoldin_2 PF01920.15 KEZ42714.1 - 5.6 6.7 31.8 7 6.4 5.3 5.2 2 1 3 5 5 5 0 Prefoldin subunit DUF745 PF05335.8 KEZ42714.1 - 6 6.3 11.6 6.5 6.2 7.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) ADH_N PF08240.7 KEZ42715.1 - 4.3e-27 94.0 1.5 6.6e-27 93.4 1.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ42715.1 - 7.4e-17 61.1 0.0 2e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ42715.1 - 0.0019 17.4 0.2 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 KEZ42716.1 - 4.5e-41 137.2 10.4 3.3e-08 33.1 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KEZ42716.1 - 3.4e-10 39.4 0.8 9.3e-10 38.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KEZ42716.1 - 2.1e-07 30.3 0.0 5.4e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KEZ42716.1 - 3.7e-06 25.3 3.2 0.1 10.7 0.0 3.9 2 1 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KEZ42716.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.11 KEZ42716.1 - 0.033 12.4 0.0 0.063 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain FlaG PF03646.10 KEZ42716.1 - 0.15 12.2 0.0 7.9 6.6 0.0 3.4 4 0 0 4 4 4 0 FlaG protein Scs3p PF10261.4 KEZ42717.1 - 4.9e-61 205.7 0.6 7e-61 205.3 0.4 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.4 KEZ42717.1 - 2e-16 59.4 0.0 4.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase G6PD_bact PF10786.4 KEZ42717.1 - 0.26 10.7 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Myb_DNA-bind_4 PF13837.1 KEZ42718.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain FAD_binding_8 PF08022.7 KEZ42719.1 - 3.5e-22 78.2 0.0 6.8e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KEZ42719.1 - 6e-22 78.2 0.0 9.3e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KEZ42719.1 - 1.8e-17 63.5 8.4 1.8e-17 63.5 5.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KEZ42719.1 - 0.00016 21.7 0.0 0.00053 20.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain AAA PF00004.24 KEZ42720.1 - 1e-17 64.5 0.0 1.8e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ42720.1 - 0.038 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain CBM_21 PF03370.8 KEZ42721.1 - 7.1e-31 106.5 0.3 7.1e-31 106.5 0.2 1.7 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit HtaA PF04213.8 KEZ42721.1 - 0.025 14.8 0.1 0.064 13.4 0.0 1.6 2 0 0 2 2 2 0 Htaa CBM_25 PF03423.8 KEZ42721.1 - 0.83 9.7 2.7 2.6 8.1 1.8 1.8 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) PseudoU_synth_1 PF01416.15 KEZ42722.1 - 2e-22 79.5 0.0 1.5e-11 44.6 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 KEZ42722.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Ndc80_HEC PF03801.8 KEZ42722.1 - 0.13 11.7 0.1 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 HEC/Ndc80p family DCP2 PF05026.8 KEZ42723.1 - 1.1e-35 121.3 0.3 2.4e-35 120.2 0.2 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KEZ42723.1 - 7.5e-17 61.2 0.0 2.1e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 KEZ42724.1 - 3.6e-35 120.0 0.3 4.8e-35 119.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HycH PF07450.6 KEZ42725.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Ribonuc_red_sm PF00268.16 KEZ42726.1 - 8.7e-122 405.5 2.3 1.1e-121 405.2 1.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 KEZ42727.1 - 1.2e-28 98.6 0.5 1.5e-28 98.3 0.4 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribosomal_L24e PF01246.15 KEZ42728.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L24e Syntaxin PF00804.20 KEZ42728.1 - 0.27 11.4 1.2 0.48 10.6 0.3 1.8 2 0 0 2 2 2 0 Syntaxin WD40 PF00400.27 KEZ42729.1 - 4.2e-18 64.4 0.2 4e-09 36.0 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KEZ42729.1 - 0.0041 15.3 0.1 0.12 10.4 0.1 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Mito_carr PF00153.22 KEZ42730.1 - 2.4e-60 200.2 1.0 1.3e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2392 PF10288.4 KEZ42731.1 - 7.4e-21 74.5 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 KEZ42731.1 - 0.0089 15.5 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 2 PP-loop family WD40 PF00400.27 KEZ42734.1 - 3.3e-20 71.1 13.6 8.1e-07 28.7 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40 PF00400.27 KEZ42735.1 - 5.5e-25 86.2 11.1 1.2e-08 34.4 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF3639 PF12341.3 KEZ42735.1 - 2e-11 43.6 1.8 8e-11 41.7 1.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KEZ42735.1 - 5.9e-08 31.9 0.0 4.2e-06 25.8 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 KEZ42735.1 - 7.4e-07 29.0 0.3 8.8e-05 22.2 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KEZ42735.1 - 0.0052 16.4 0.2 41 3.9 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 KEZ42735.1 - 0.013 13.3 0.1 0.14 9.9 0.1 2.1 1 1 0 2 2 2 0 IKI3 family HSF_DNA-bind PF00447.12 KEZ42736.1 - 4.7e-09 36.3 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF605 PF04652.11 KEZ42736.1 - 0.41 9.9 14.9 0.46 9.8 10.3 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 KEZ42736.1 - 3.8 6.0 8.7 4.2 5.9 6.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HSF_DNA-bind PF00447.12 KEZ42737.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Asp PF00026.18 KEZ42738.1 - 1.8e-16 60.3 0.0 4.7e-16 58.9 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KEZ42738.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Ndc1_Nup PF09531.5 KEZ42739.1 - 4.8e-128 428.2 0.0 5.4e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 KEZ42740.1 - 1.5e-20 73.1 4.2 1.5e-20 73.1 2.9 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 KEZ42740.1 - 2.5e-16 59.0 4.0 2.5e-16 59.0 2.8 2.0 2 0 0 2 2 2 1 SNARE domain DUF3552 PF12072.3 KEZ42740.1 - 0.056 12.6 14.1 0.049 12.8 8.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) APC_CDC26 PF10471.4 KEZ42740.1 - 2 9.2 6.7 5.8 7.7 4.7 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF16 PF01519.11 KEZ42740.1 - 2.6 8.2 9.8 1.1e+02 3.0 6.7 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Presenilin PF01080.12 KEZ42740.1 - 9.6 4.9 9.1 2.1 7.0 1.7 2.0 2 0 0 2 2 2 0 Presenilin Glycos_transf_1 PF00534.15 KEZ42741.1 - 9.1e-22 77.2 0.0 1.5e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEZ42741.1 - 1.6e-10 41.2 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KEZ42741.1 - 0.00048 19.8 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 G_glu_transpept PF01019.16 KEZ42742.1 - 1e-162 542.2 0.0 1.1e-162 542.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase P22_CoatProtein PF11651.3 KEZ42742.1 - 0.0024 16.5 0.1 0.0037 15.9 0.0 1.3 1 0 0 1 1 1 1 P22 coat protein - gene protein 5 DUF1344 PF07076.6 KEZ42742.1 - 0.073 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) UNC45-central PF11701.3 KEZ42743.1 - 3.2e-48 163.3 0.5 3.4e-45 153.4 0.0 3.3 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KEZ42743.1 - 5.8e-09 36.1 13.1 0.0081 16.4 1.5 5.7 4 1 1 6 6 6 3 HEAT repeats HEAT PF02985.17 KEZ42743.1 - 1.9e-06 27.4 6.8 0.024 14.6 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KEZ42743.1 - 0.00035 20.9 12.8 3.5 8.2 0.4 6.6 7 0 0 7 7 7 2 HEAT-like repeat CLASP_N PF12348.3 KEZ42743.1 - 0.0035 16.7 0.3 0.017 14.4 0.0 2.2 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.18 KEZ42743.1 - 0.0044 16.7 17.3 4.8 7.1 0.1 7.7 7 1 0 7 7 7 2 Armadillo/beta-catenin-like repeat Asparaginase_2 PF01112.13 KEZ42744.1 - 4.2e-32 111.1 1.5 2.5e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.14 KEZ42745.1 - 2.5e-87 292.8 0.0 5.7e-87 291.7 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEZ42745.1 - 0.074 11.6 0.1 2.3 6.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein HMA PF00403.21 KEZ42746.1 - 1.2e-15 57.3 0.3 1.7e-15 56.8 0.2 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Glyco_hydro_61 PF03443.9 KEZ42747.1 - 8.3e-62 208.8 0.7 1.4e-61 208.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 DUF605 PF04652.11 KEZ42747.1 - 0.18 11.1 12.1 0.26 10.6 8.4 1.2 1 0 0 1 1 1 0 Vta1 like SART-1 PF03343.8 KEZ42747.1 - 0.28 9.4 4.2 0.37 9.0 2.9 1.0 1 0 0 1 1 1 0 SART-1 family DUF4551 PF15087.1 KEZ42747.1 - 4.6 5.4 6.2 6.1 5.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Thiolase_C PF02803.13 KEZ42749.1 - 2.3e-12 46.4 0.8 1.1e-11 44.1 0.1 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KEZ42749.1 - 3.1e-05 23.5 0.6 0.0025 17.4 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 KEZ42749.1 - 0.011 15.5 0.1 0.46 10.3 0.0 2.9 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KEZ42749.1 - 0.011 14.7 4.9 0.07 12.1 0.1 3.6 4 0 0 4 4 4 0 Thiolase, N-terminal domain Fungal_trans PF04082.13 KEZ42750.1 - 7.4e-16 57.7 0.2 1.3e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ42750.1 - 3.4e-06 26.8 18.9 7.7e-06 25.7 13.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tcf25 PF04910.9 KEZ42751.1 - 6.6e-69 232.5 2.6 1.7e-68 231.1 1.8 1.7 1 1 0 1 1 1 1 Transcriptional repressor TCF25 TEX19 PF15553.1 KEZ42751.1 - 0.34 10.7 6.1 0.95 9.3 4.2 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 Nop53 PF07767.6 KEZ42751.1 - 0.39 9.6 20.9 0.7 8.8 14.5 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Peptidase_C37 PF05416.7 KEZ42751.1 - 3.4 5.8 7.8 6.7 4.8 5.4 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Daxx PF03344.10 KEZ42751.1 - 5.1 5.4 20.2 7.8 4.8 14.0 1.2 1 0 0 1 1 1 0 Daxx Family LSM14 PF12701.2 KEZ42752.1 - 3e-33 113.4 0.1 6.2e-33 112.4 0.1 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KEZ42752.1 - 2.8e-21 75.9 3.9 2.8e-21 75.9 2.7 2.0 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KEZ42752.1 - 3.7e-06 26.7 0.1 9.7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain Pyr_redox_2 PF07992.9 KEZ42753.1 - 1.1e-37 129.8 1.7 1.9e-37 129.1 0.7 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KEZ42753.1 - 3.5e-34 117.1 0.3 1.4e-33 115.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KEZ42753.1 - 3.8e-19 68.8 4.6 2.7e-17 62.9 0.1 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ42753.1 - 3.5e-14 53.3 0.3 7.3e-11 42.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ42753.1 - 0.00019 20.0 1.7 0.68 8.3 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 KEZ42753.1 - 0.00086 18.3 0.1 0.53 9.1 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KEZ42753.1 - 0.00087 18.4 0.6 0.0045 16.1 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ42753.1 - 0.0024 17.0 0.1 0.0061 15.6 0.1 1.8 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KEZ42753.1 - 0.0054 15.6 0.2 0.033 13.0 0.1 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KEZ42753.1 - 0.052 13.1 2.5 0.053 13.1 0.0 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KEZ42753.1 - 0.08 11.7 7.7 0.61 8.8 0.6 3.0 4 0 0 4 4 4 0 FAD binding domain DUF2138 PF09909.4 KEZ42753.1 - 0.17 9.9 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) NAD_binding_8 PF13450.1 KEZ42753.1 - 1.4 9.0 4.1 0.71 9.9 0.8 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEZ42753.1 - 1.8 7.5 5.1 1.7 7.6 0.5 2.7 2 1 1 3 3 3 0 FAD binding domain DAO PF01266.19 KEZ42753.1 - 5.4 5.8 12.6 3.4 6.4 0.9 3.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase OB_NTP_bind PF07717.11 KEZ42754.1 - 1.8e-23 82.5 0.0 3.3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KEZ42754.1 - 1.7e-20 72.9 0.1 4.2e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KEZ42754.1 - 1.5e-12 47.1 0.0 3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ42754.1 - 0.00012 21.6 0.2 0.00063 19.2 0.2 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEZ42754.1 - 0.00044 20.3 0.2 0.0027 17.8 0.1 2.4 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 KEZ42754.1 - 0.011 15.5 0.7 11 5.8 0.0 3.5 4 1 1 5 5 5 0 Type III restriction enzyme, res subunit cobW PF02492.14 KEZ42754.1 - 0.017 14.5 0.2 0.27 10.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KEZ42754.1 - 0.021 13.8 0.1 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 KEZ42754.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEZ42754.1 - 0.065 12.1 0.2 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.17 KEZ42754.1 - 0.068 12.6 0.7 2 7.7 0.1 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 KEZ42754.1 - 0.078 12.8 0.1 1.2 9.0 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ42754.1 - 0.22 11.2 0.9 0.75 9.5 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain Ank_2 PF12796.2 KEZ42755.1 - 5e-55 183.8 0.0 4.4e-17 62.2 0.0 6.3 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ42755.1 - 3.2e-50 165.5 8.7 4.9e-08 32.4 0.1 11.6 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 KEZ42755.1 - 5.6e-38 128.6 2.9 1.1e-09 38.5 0.0 9.0 6 3 4 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ42755.1 - 1.3e-35 120.5 9.1 9.3e-09 35.2 0.2 9.0 8 2 1 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ42755.1 - 2.1e-31 104.8 10.9 0.00011 22.0 0.0 11.7 13 0 0 13 13 13 7 Ankyrin repeat Pkinase PF00069.20 KEZ42755.1 - 3.5e-25 88.6 0.0 5.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42755.1 - 2.5e-20 72.6 0.0 4.1e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF294 PF03445.8 KEZ42755.1 - 0.0069 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 Sel1 PF08238.7 KEZ42755.1 - 0.034 14.7 0.0 0.17 12.5 0.0 2.3 1 0 0 1 1 1 0 Sel1 repeat HeLo PF14479.1 KEZ42756.1 - 7.1e-15 55.3 0.4 1.2e-14 54.6 0.3 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 KEZ42756.1 - 7.1e-07 28.6 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42756.1 - 3e-05 23.2 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase efThoc1 PF11957.3 KEZ42756.1 - 0.054 11.9 0.0 0.1 11.0 0.0 1.4 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor SKG6 PF08693.5 KEZ42757.1 - 0.00034 19.8 0.5 0.00055 19.1 0.3 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2232 PF09991.4 KEZ42757.1 - 0.3 10.0 0.1 0.43 9.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SKG6 PF08693.5 KEZ42758.1 - 1.9e-05 23.8 4.1 3.6e-05 22.9 2.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KEZ42758.1 - 0.00029 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 KEZ42758.1 - 0.0086 15.7 0.1 0.025 14.3 0.0 1.7 1 1 0 1 1 1 1 TMEM154 protein family DUF4366 PF14283.1 KEZ42758.1 - 0.029 13.7 2.0 0.23 10.8 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3609 PF12259.3 KEZ42758.1 - 0.15 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF3377 PF11857.3 KEZ42758.1 - 0.18 11.4 0.0 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Herpes_gE PF02480.11 KEZ42758.1 - 0.43 8.8 0.0 0.43 8.8 0.0 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E COesterase PF00135.23 KEZ42759.1 - 3.1e-93 313.3 0.0 3.9e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ42759.1 - 3.1e-07 30.1 1.9 3.2e-06 26.8 1.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ42759.1 - 0.012 15.3 0.3 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3632 PF12311.3 KEZ42761.1 - 1.5e-32 112.8 0.6 2e-32 112.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DASH_Dad2 PF08654.5 KEZ42762.1 - 6.5e-29 99.9 5.0 6.5e-29 99.9 3.5 2.3 2 1 0 2 2 2 1 DASH complex subunit Dad2 NmrA PF05368.8 KEZ42763.1 - 1e-26 93.6 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ42763.1 - 1.2e-17 64.5 0.0 2.2e-17 63.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEZ42763.1 - 0.00014 20.9 0.3 0.00027 20.0 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 KEZ42763.1 - 0.0011 18.4 0.0 0.0087 15.5 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 KEZ42763.1 - 0.004 17.0 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 KEZ42763.1 - 0.014 14.0 0.1 0.11 11.2 0.0 2.2 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEZ42763.1 - 0.053 13.8 0.2 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shugoshin_N PF07558.6 KEZ42764.1 - 7.7e-12 44.7 6.8 7.7e-12 44.7 4.7 2.6 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KEZ42764.1 - 6.6e-11 41.4 6.6 6.6e-11 41.4 4.6 3.8 4 0 0 4 4 4 1 Shugoshin C terminus AKNA PF12443.3 KEZ42764.1 - 0.0057 16.6 0.9 0.016 15.2 0.6 1.7 1 0 0 1 1 1 1 AT-hook-containing transcription factor DivIC PF04977.10 KEZ42764.1 - 0.2 11.1 2.6 6.7 6.2 1.3 2.7 2 0 0 2 2 2 0 Septum formation initiator Metallophos_2 PF12850.2 KEZ42765.1 - 5.2e-13 49.1 0.0 6.6e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KEZ42765.1 - 0.015 14.7 0.0 0.13 11.6 0.0 2.0 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Aminotran_5 PF00266.14 KEZ42766.1 - 1.3e-28 99.8 0.0 1.7e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KEZ42766.1 - 0.019 13.2 0.0 0.026 12.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 KEZ42766.1 - 0.028 14.2 0.1 0.098 12.5 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain CRM1_C PF08767.6 KEZ42767.1 - 1.2e-130 435.0 1.3 1.2e-130 435.0 0.9 3.2 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 KEZ42767.1 - 2e-40 138.0 9.1 2e-40 138.0 6.3 3.5 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KEZ42767.1 - 1.4e-09 37.6 0.0 6.2e-09 35.6 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 KEZ42767.1 - 0.088 13.2 3.5 2 8.8 0.0 4.6 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.3 KEZ42767.1 - 0.14 12.0 0.1 0.14 12.0 0.0 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) C8 PF08742.6 KEZ42767.1 - 0.36 11.0 2.9 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 C8 domain RGS PF00615.14 KEZ42770.1 - 4.9e-05 23.4 0.0 0.00027 21.0 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_23 PF13489.1 KEZ42771.1 - 9.5e-13 48.1 0.0 8.1e-12 45.1 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42771.1 - 5.7e-08 33.1 0.0 1.5e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42771.1 - 0.00058 20.2 0.0 0.0021 18.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ42771.1 - 0.00082 18.5 0.0 0.0019 17.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ42771.1 - 0.0085 16.4 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42771.1 - 0.03 13.8 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain VDE PF07137.6 KEZ42771.1 - 0.081 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) Aldolase_II PF00596.16 KEZ42772.1 - 2.7e-49 167.2 0.1 3.4e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain dCMP_cyt_deam_1 PF00383.17 KEZ42773.1 - 4.6e-20 71.1 1.8 1.9e-19 69.1 0.8 2.2 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KEZ42773.1 - 0.00035 20.4 0.6 0.019 14.8 0.0 2.3 2 0 0 2 2 2 2 Bd3614-like deaminase SH3_1 PF00018.23 KEZ42774.1 - 5.9e-14 51.1 0.1 1.1e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ42774.1 - 9.6e-14 50.7 0.1 1.6e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEZ42774.1 - 7.9e-12 44.4 0.1 1.5e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.13 KEZ42774.1 - 2.2e-11 43.6 0.1 3.3e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 BAR domain HoxA13_N PF12284.3 KEZ42775.1 - 0.071 13.2 0.8 0.17 12.0 0.6 1.7 1 0 0 1 1 1 0 Hox protein A13 N terminal Bot1p PF12298.3 KEZ42776.1 - 5.7e-51 172.8 1.0 7.2e-51 172.5 0.4 1.3 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.19 KEZ42777.1 - 1.2e-19 70.4 0.0 8.3e-14 51.5 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.4 KEZ42778.1 - 6.5e-31 107.6 7.4 8.3e-31 107.3 5.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) L51_S25_CI-B8 PF05047.11 KEZ42779.1 - 4.3e-12 45.5 0.1 7.3e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 KEZ42780.1 - 6.8e-42 142.2 0.5 1.1e-41 141.5 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 KEZ42780.1 - 0.00052 19.8 0.4 0.00076 19.3 0.3 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange Ank_2 PF12796.2 KEZ42781.1 - 6e-10 39.3 0.0 1.4e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ42781.1 - 3.4e-09 36.0 0.0 0.04 13.7 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KEZ42781.1 - 5.2e-09 35.4 0.1 0.033 14.4 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEZ42781.1 - 4.5e-08 33.3 0.0 1e-05 25.8 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ42781.1 - 2.5e-07 30.7 0.1 0.22 11.8 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) HSP70 PF00012.15 KEZ42782.1 - 1.3e-11 43.1 0.2 5.7e-10 37.7 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 KEZ42782.1 - 0.0041 16.7 0.1 0.0092 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KEZ42782.1 - 0.017 13.7 0.0 0.086 11.4 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_1 PF00349.16 KEZ42783.1 - 1.9e-66 223.3 0.1 2.6e-66 222.8 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KEZ42783.1 - 1.4e-64 217.5 0.0 2.5e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DUF2732 PF10809.3 KEZ42784.1 - 0.01 15.3 0.1 0.021 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) DGCR6 PF07324.6 KEZ42784.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Sgf11 PF08209.6 KEZ42784.1 - 2.3 7.6 7.6 0.23 10.7 2.2 1.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.16 KEZ42785.1 - 8e-50 169.0 0.0 9.1e-50 168.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 KEZ42786.1 - 4.5e-48 164.2 14.3 1.8e-46 158.9 9.9 2.8 1 1 0 1 1 1 1 Signal peptide peptidase UPF0233 PF06781.7 KEZ42786.1 - 0.056 13.0 0.2 0.52 9.9 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) ACPS PF01648.15 KEZ42787.1 - 6e-12 45.4 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SRP-alpha_N PF04086.8 KEZ42788.1 - 9e-69 231.9 5.6 2.8e-68 230.3 3.9 1.7 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KEZ42788.1 - 2.7e-52 177.0 0.1 4.5e-52 176.3 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KEZ42788.1 - 5.8e-08 32.7 0.2 4e-07 30.0 0.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KEZ42788.1 - 3.3e-05 22.8 0.0 6.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KEZ42788.1 - 0.00084 18.7 0.2 0.0029 17.0 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KEZ42788.1 - 0.019 14.6 0.1 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CinA PF02464.12 KEZ42788.1 - 0.024 14.1 0.2 0.024 14.1 0.1 1.7 2 0 0 2 2 2 0 Competence-damaged protein MMR_HSR1 PF01926.18 KEZ42788.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KEZ42788.1 - 0.034 14.4 0.0 0.15 12.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KEZ42788.1 - 0.076 12.9 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KEZ42788.1 - 0.11 12.6 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain YIF1 PF03878.10 KEZ42789.1 - 2.8e-59 200.1 4.8 5.2e-42 143.6 0.2 2.0 1 1 1 2 2 2 2 YIF1 Yip1 PF04893.12 KEZ42789.1 - 0.18 11.2 7.7 0.42 10.0 5.0 1.8 1 1 0 1 1 1 0 Yip1 domain Amidase PF01425.16 KEZ42790.1 - 4.9e-50 170.6 0.0 5.7e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 KEZ42791.1 - 2.7e-46 157.8 49.4 1.2e-45 155.7 22.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ42791.1 - 5.2e-11 41.7 19.7 6.5e-10 38.1 8.8 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 KEZ42791.1 - 0.00035 18.7 8.8 0.0034 15.5 0.0 2.8 2 1 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KEZ42791.1 - 0.0012 17.0 0.4 0.0012 17.0 0.3 2.2 1 1 2 3 3 3 1 Transmembrane secretion effector zf-DHHC PF01529.15 KEZ42791.1 - 1.9 7.8 4.9 2.2 7.6 0.0 2.9 3 1 0 3 3 3 0 DHHC palmitoyltransferase AMP-binding PF00501.23 KEZ42792.1 - 5.6e-81 272.0 0.0 9.4e-81 271.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KEZ42792.1 - 7e-65 219.0 0.0 1.6e-64 217.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEZ42792.1 - 1.5e-52 177.8 0.0 9.7e-52 175.2 0.0 2.3 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 KEZ42792.1 - 6e-47 160.5 0.0 1.1e-46 159.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KEZ42792.1 - 1.3e-46 159.1 0.0 2.1e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEZ42792.1 - 8.5e-46 155.9 0.0 1e-42 145.8 0.0 3.2 3 0 0 3 3 2 1 short chain dehydrogenase Condensation PF00668.15 KEZ42792.1 - 3e-36 124.8 0.0 6.5e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 KEZ42792.1 - 4.7e-31 107.0 0.2 1.3e-30 105.6 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KEZ42792.1 - 3.9e-26 91.4 0.0 1.4e-25 89.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KEZ42792.1 - 5.4e-20 71.4 0.2 8.7e-12 45.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEZ42792.1 - 2.1e-18 66.6 0.0 5.7e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KEZ42792.1 - 3e-11 43.2 0.0 2.8e-08 33.4 0.0 3.2 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 KEZ42792.1 - 2.4e-10 39.7 0.0 4.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 KEZ42792.1 - 3.8e-10 39.7 0.0 9.9e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42792.1 - 1.1e-09 38.8 0.0 6.5e-09 36.3 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42792.1 - 2.3e-09 37.6 0.0 6.2e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42792.1 - 1.5e-08 34.3 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Zn_clus PF00172.13 KEZ42792.1 - 3.2e-08 33.3 10.5 6e-08 32.4 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HxxPF_rpt PF13745.1 KEZ42792.1 - 3.2e-07 30.5 0.0 2.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 HxxPF-repeated domain Thiolase_N PF00108.18 KEZ42792.1 - 3.1e-05 23.0 0.0 6.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KEZ42792.1 - 0.0014 17.3 0.0 0.065 11.9 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 KEZ42792.1 - 0.0021 17.2 0.0 0.0074 15.4 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Semialdhyde_dh PF01118.19 KEZ42792.1 - 0.0024 18.1 0.0 0.049 13.9 0.0 2.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KEZ42792.1 - 0.0041 16.0 0.0 0.019 13.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain RrnaAD PF00398.15 KEZ42792.1 - 0.056 12.4 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Mpv17_PMP22 PF04117.7 KEZ42793.1 - 9.6e-15 53.9 1.1 9.6e-15 53.9 0.8 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family ARPC4 PF05856.7 KEZ42794.1 - 1.4e-70 236.0 4.0 1.6e-70 235.9 2.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) CRAL_TRIO PF00650.15 KEZ42796.1 - 4e-14 52.4 0.0 5.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEZ42796.1 - 0.00069 19.7 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SET PF00856.23 KEZ42797.1 - 1.4e-19 70.9 1.3 1.4e-19 70.9 0.9 3.8 4 3 0 4 4 4 1 SET domain Tim54 PF11711.3 KEZ42797.1 - 2.5 6.5 11.2 0.016 13.8 0.9 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 zf-DHHC PF01529.15 KEZ42798.1 - 5e-28 97.6 0.2 5e-28 97.6 0.1 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Phage_holin_6 PF10746.4 KEZ42798.1 - 0.0073 16.0 1.0 0.016 14.8 0.7 1.5 1 0 0 1 1 1 1 Phage holin family 6 DUF4106 PF13388.1 KEZ42798.1 - 1.3 7.9 5.8 1.9 7.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ABC2_membrane_3 PF12698.2 KEZ42798.1 - 1.7 7.5 14.9 0.91 8.4 2.4 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein FAM75 PF14650.1 KEZ42798.1 - 1.8 7.8 9.7 2.7 7.2 6.7 1.1 1 0 0 1 1 1 0 FAM75 family IMS PF00817.15 KEZ42799.1 - 9e-41 139.1 0.0 1.4e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEZ42799.1 - 1.7e-10 40.9 0.1 3.2e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-C2H2 PF00096.21 KEZ42799.1 - 0.0047 17.1 0.2 0.014 15.7 0.2 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type IMS_HHH PF11798.3 KEZ42799.1 - 0.0061 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-met PF12874.2 KEZ42799.1 - 0.016 15.4 0.1 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type IBN_N PF03810.14 KEZ42801.1 - 1.9e-13 50.1 2.9 4.6e-11 42.4 0.0 3.7 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.5 KEZ42801.1 - 2.2e-08 33.0 0.1 6.5e-08 31.5 0.0 1.8 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 KEZ42801.1 - 3.9e-05 23.6 2.9 0.00027 20.8 0.0 3.6 4 0 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 KEZ42801.1 - 0.00012 22.3 2.4 0.67 10.2 0.1 3.9 2 1 1 3 3 3 3 HEAT repeats GRIP PF01465.15 KEZ42801.1 - 0.013 15.0 0.6 0.098 12.1 0.0 2.9 3 0 0 3 3 3 0 GRIP domain YHS PF04945.8 KEZ42801.1 - 0.025 14.4 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 YHS domain HEAT PF02985.17 KEZ42801.1 - 0.33 11.1 1.9 0.77 10.0 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 KEZ42801.1 - 5 7.7 10.8 17 6.0 0.0 5.6 7 0 0 7 7 7 0 HEAT-like repeat Pkinase PF00069.20 KEZ42803.1 - 3.1e-55 187.1 0.0 4.1e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42803.1 - 7e-26 90.8 0.0 4.2e-25 88.3 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42803.1 - 0.043 12.7 0.1 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like ISN1 PF06437.6 KEZ42804.1 - 1.8e-182 606.6 0.0 2e-182 606.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF2404 PF10296.4 KEZ42805.1 - 2.4e-32 110.9 0.0 5.5e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Autophagy_N PF03986.8 KEZ42806.1 - 5.8e-43 146.1 2.2 1.2e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KEZ42806.1 - 1.1e-22 79.9 0.2 2.6e-22 78.7 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KEZ42806.1 - 1.4e-14 52.8 0.4 2.5e-14 52.0 0.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF718 PF05336.8 KEZ42807.1 - 6.3e-36 122.4 0.2 7.5e-36 122.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Cellulase-like PF12876.2 KEZ42808.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF943 PF06092.7 KEZ42809.1 - 0.17 11.1 2.1 0.29 10.4 1.5 1.3 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) DUF605 PF04652.11 KEZ42809.1 - 2.4 7.4 28.1 0.051 12.9 8.4 2.2 2 0 0 2 2 2 0 Vta1 like DUF2348 PF09807.4 KEZ42810.1 - 0.0035 16.4 0.1 0.0079 15.3 0.0 1.6 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2348) Ribosomal_L37e PF01907.14 KEZ42811.1 - 5.4e-28 96.5 11.6 8.5e-28 95.9 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KEZ42811.1 - 0.0033 17.1 1.3 0.0054 16.5 0.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KEZ42811.1 - 0.04 13.1 1.4 0.096 11.9 1.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.14 KEZ42811.1 - 0.19 11.4 1.0 0.26 10.9 0.7 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C4pol PF14260.1 KEZ42811.1 - 0.21 11.6 2.6 0.34 10.9 1.5 1.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Ribosomal_S14 PF00253.16 KEZ42811.1 - 0.33 10.3 10.5 0.53 9.7 0.3 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 KEZ42811.1 - 7 6.3 10.7 14 5.3 3.1 2.3 1 1 1 2 2 2 0 Ribosomal L40e family UPF0016 PF01169.14 KEZ42812.1 - 1.1e-40 137.5 24.9 4.6e-22 77.9 4.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 WD40 PF00400.27 KEZ42813.1 - 8.5e-21 73.0 7.7 8.9e-08 31.7 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KEZ42813.1 - 0.094 10.9 1.1 7.6 4.7 0.0 3.1 2 1 2 4 4 4 0 Cytochrome D1 heme domain RRM_6 PF14259.1 KEZ42814.1 - 2.8e-07 30.4 0.0 4.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ42814.1 - 0.00015 21.3 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ42814.1 - 0.0037 17.0 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apc5 PF12862.2 KEZ42815.1 - 5.1e-31 106.3 3.1 5.1e-31 106.3 2.1 2.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_4 PF07721.9 KEZ42815.1 - 0.0034 17.6 6.4 0.037 14.4 0.5 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4351 PF14261.1 KEZ42815.1 - 0.0041 16.9 0.2 0.018 14.8 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4351) TPR_10 PF13374.1 KEZ42815.1 - 0.078 12.9 5.9 1.1 9.3 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L21e PF01157.13 KEZ42816.1 - 1.5e-39 133.8 3.4 2e-39 133.3 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF3865 PF12981.2 KEZ42816.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Ribosomal_S4 PF00163.14 KEZ42817.1 - 3.8e-29 100.8 1.2 7.2e-29 100.0 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KEZ42817.1 - 4.2e-13 48.4 1.2 4.2e-13 48.4 0.8 2.6 3 0 0 3 3 3 1 S4 domain EST1_DNA_bind PF10373.4 KEZ42818.1 - 4.3e-09 35.9 0.1 3.4e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain Amastin PF07344.6 KEZ42819.1 - 1.3 8.5 14.3 0.38 10.3 0.8 2.6 3 0 0 3 3 3 0 Amastin surface glycoprotein EmrE PF13536.1 KEZ42819.1 - 4.8 7.4 11.1 6 7.1 2.1 2.6 1 1 0 2 2 2 0 Multidrug resistance efflux transporter bZIP_2 PF07716.10 KEZ42820.1 - 0.0089 15.8 10.2 0.016 15.0 7.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KEZ42820.1 - 0.015 15.1 11.1 0.021 14.7 6.8 1.8 1 1 1 2 2 2 0 bZIP transcription factor RFXA_RFXANK_bdg PF15289.1 KEZ42820.1 - 0.043 13.9 1.3 0.088 13.0 0.9 1.4 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain bZIP_Maf PF03131.12 KEZ42820.1 - 2.5 8.4 9.7 4 7.7 6.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor UPF0242 PF06785.6 KEZ42821.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TPR_12 PF13424.1 KEZ42822.1 - 0.00016 21.5 0.2 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat NPV_P10 PF05531.7 KEZ42822.1 - 0.00082 19.5 1.1 0.0032 17.6 0.8 2.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein TPR_19 PF14559.1 KEZ42822.1 - 0.0032 17.7 0.2 0.37 11.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KEZ42822.1 - 0.0045 17.0 0.5 0.22 11.6 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KEZ42822.1 - 0.022 14.3 0.2 0.22 11.1 0.0 2.3 1 1 1 2 2 2 0 TPR repeat TPR_10 PF13374.1 KEZ42822.1 - 1.2 9.1 3.7 7.1 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANTH PF07651.11 KEZ42823.1 - 5e-82 274.7 0.0 5e-82 274.7 0.0 2.4 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KEZ42823.1 - 4.2e-63 211.8 7.8 4.2e-63 211.8 5.4 5.3 6 1 1 7 7 7 1 I/LWEQ domain ENTH PF01417.15 KEZ42823.1 - 6.5e-06 26.0 0.3 2.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 ENTH domain Reo_sigmaC PF04582.7 KEZ42823.1 - 0.4 9.7 8.0 0.38 9.8 2.4 2.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein MAT_Alpha1 PF04769.7 KEZ42824.1 - 1.6e-45 154.9 0.0 3.7e-45 153.7 0.0 1.5 1 1 1 2 2 2 1 Mating-type protein MAT alpha 1 NOA36 PF06524.7 KEZ42825.1 - 0.00016 21.0 3.6 0.0002 20.7 2.5 1.3 1 0 0 1 1 1 1 NOA36 protein FYDLN_acid PF09538.5 KEZ42825.1 - 0.016 15.7 15.8 0.04 14.5 9.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.7 KEZ42825.1 - 0.32 8.8 22.9 0.35 8.7 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 KEZ42825.1 - 1.1 9.1 19.2 1.7 8.5 13.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1510 PF07423.6 KEZ42825.1 - 1.8 7.8 15.8 2.7 7.3 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CobT PF06213.7 KEZ42825.1 - 2.5 7.1 22.8 3.2 6.7 15.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VID27 PF08553.5 KEZ42825.1 - 2.8 6.0 13.8 2.9 6.0 9.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pox_Ag35 PF03286.9 KEZ42825.1 - 3.8 7.0 13.5 5.6 6.4 9.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.6 KEZ42825.1 - 6 4.5 10.7 8.4 4.1 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COX6A PF02046.10 KEZ42826.1 - 1.1e-45 154.2 2.2 1.3e-45 154.0 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2984 PF11203.3 KEZ42826.1 - 0.17 11.9 1.0 0.33 11.0 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2984) dsDNA_bind PF01984.15 KEZ42827.1 - 1.2e-33 115.3 18.3 1.3e-33 115.1 12.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 KEZ42827.1 - 0.0034 17.6 1.4 0.0034 17.6 1.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4615) Fes1 PF08609.5 KEZ42827.1 - 0.027 14.9 2.8 0.037 14.5 0.6 1.9 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Imm35 PF15581.1 KEZ42827.1 - 0.056 13.4 0.4 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Immunity protein 35 Peptidase_C58 PF03543.9 KEZ42827.1 - 0.75 9.2 6.0 1 8.7 4.2 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF1266 PF06889.6 KEZ42827.1 - 1.5 8.6 4.8 2.6 7.8 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) MFS_1 PF07690.11 KEZ42828.1 - 3.1e-36 124.8 48.5 1.1e-35 122.9 33.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily WBP-1 PF11669.3 KEZ42828.1 - 0.02 14.9 0.1 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 Corona_S2 PF01601.11 KEZ42828.1 - 0.29 9.1 1.5 0.47 8.4 1.1 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein MarR_2 PF12802.2 KEZ42830.1 - 0.1 12.2 0.2 5 6.8 0.0 2.7 2 0 0 2 2 2 0 MarR family DUF4360 PF14273.1 KEZ42831.1 - 1.4e-06 28.0 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) FeoC PF09012.5 KEZ42832.1 - 2.2 8.0 4.8 0.81 9.4 0.1 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator SurE PF01975.12 KEZ42834.1 - 2.8e-27 95.3 0.1 8.1e-27 93.8 0.0 1.8 1 1 1 2 2 2 1 Survival protein SurE Cu_amine_oxid PF01179.15 KEZ42835.1 - 4.5e-166 552.6 0.0 5.6e-166 552.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KEZ42835.1 - 7.3e-11 42.0 0.2 1.5e-10 41.0 0.2 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KEZ42835.1 - 0.0025 17.8 0.1 0.0067 16.4 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Ank_2 PF12796.2 KEZ42836.1 - 8.9e-34 115.7 0.1 1.2e-18 67.2 0.0 4.5 1 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ42836.1 - 8.2e-27 91.6 8.0 6e-09 35.2 0.2 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 KEZ42836.1 - 5.6e-21 74.1 8.2 1.2e-11 44.4 0.4 6.8 5 2 3 8 8 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ42836.1 - 4.6e-17 62.0 5.2 1e-11 44.9 0.1 6.4 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ42836.1 - 3.5e-16 57.7 0.3 0.0057 16.7 0.0 8.5 8 0 0 8 8 8 3 Ankyrin repeat AAA_16 PF13191.1 KEZ42836.1 - 1.3e-10 41.5 0.3 6.3e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KEZ42836.1 - 4.1e-09 36.3 0.0 4.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ42836.1 - 5e-06 26.6 0.0 5.5e-05 23.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain FlxA PF14282.1 KEZ42836.1 - 0.012 15.4 1.2 0.03 14.2 0.8 1.6 1 0 0 1 1 1 0 FlxA-like protein Viral_helicase1 PF01443.13 KEZ42836.1 - 0.02 14.3 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KEZ42836.1 - 0.029 14.5 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Baculo_PEP_C PF04513.7 KEZ42836.1 - 0.062 13.1 3.2 0.17 11.6 0.4 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_14 PF13173.1 KEZ42836.1 - 0.065 13.1 0.0 0.5 10.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain CorA PF01544.13 KEZ42836.1 - 0.075 12.0 2.6 0.12 11.3 0.2 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Peptidase_M28 PF04389.12 KEZ42837.1 - 5.7e-35 120.6 0.0 9.6e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEZ42837.1 - 1.6e-14 53.4 0.9 2.7e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KEZ42837.1 - 0.0024 17.3 0.1 0.0078 15.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KEZ42837.1 - 0.0026 16.5 0.0 0.015 14.1 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase MFS_1 PF07690.11 KEZ42839.1 - 1.2e-13 50.5 13.4 1.2e-12 47.2 10.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIIE-A_C-term PF11521.3 KEZ42839.1 - 0.035 14.0 1.2 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha MFS_1 PF07690.11 KEZ42840.1 - 4.6e-32 111.1 69.8 6e-18 64.6 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ42840.1 - 0.0028 16.1 34.0 0.028 12.8 12.6 3.3 1 1 2 3 3 3 3 MFS/sugar transport protein FAD_binding_4 PF01565.18 KEZ42841.1 - 1.8e-19 69.5 2.6 4.9e-19 68.1 1.4 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEZ42841.1 - 0.0015 18.3 1.4 0.0035 17.1 1.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Jiraiya PF15038.1 KEZ42842.1 - 0.092 12.1 1.2 0.2 11.0 0.8 1.5 1 0 0 1 1 1 0 Jiraiya MFS_1 PF07690.11 KEZ42843.1 - 9.1e-18 64.0 19.1 1.2e-17 63.7 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_10 PF00331.15 KEZ42845.1 - 1.3e-97 326.6 0.2 1.5e-97 326.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_3 PF00933.16 KEZ42847.1 - 1.9e-81 273.3 0.0 2.7e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ42847.1 - 1.1e-61 208.2 0.1 2.7e-61 206.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ42847.1 - 1.5e-19 69.6 0.2 3.8e-19 68.3 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Lgl_C PF08596.5 KEZ42848.1 - 2.6e-120 401.5 0.0 6.6e-120 400.1 0.0 1.6 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KEZ42848.1 - 1.5e-07 30.9 3.8 0.01 15.6 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KEZ42848.1 - 0.025 12.7 0.0 4.6 5.2 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 zf-C2H2_4 PF13894.1 KEZ42850.1 - 1.3e-06 28.2 5.5 0.00014 21.9 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ42850.1 - 3.2e-06 27.1 5.0 0.00079 19.6 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 KEZ42850.1 - 0.042 14.0 0.5 0.042 14.0 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Amidohydro_2 PF04909.9 KEZ42851.1 - 8.3e-11 41.9 0.1 1.4e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KEZ42851.1 - 1.1e-06 28.9 0.5 2.1e-06 27.9 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KEZ42851.1 - 0.0015 18.2 0.1 0.0042 16.7 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 KEZ42851.1 - 0.051 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 CoA binding domain NAD_binding_6 PF08030.7 KEZ42851.1 - 0.17 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Piwi PF02171.12 KEZ42852.1 - 4.5e-82 275.3 0.1 6.2e-82 274.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KEZ42852.1 - 1.4e-13 50.3 0.0 2.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KEZ42852.1 - 3e-09 36.1 0.0 9.5e-09 34.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) UPF0175 PF03683.8 KEZ42852.1 - 0.22 11.0 0.0 0.55 9.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Suf PF05843.9 KEZ42853.1 - 1.5e-79 267.6 0.1 6.2e-78 262.3 0.0 3.1 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KEZ42853.1 - 1.4e-05 25.2 7.0 0.019 15.5 0.2 5.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ42853.1 - 0.00091 19.8 3.5 0.0044 17.6 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ42853.1 - 0.005 17.1 0.0 0.7 10.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ42853.1 - 0.014 15.0 0.1 0.55 9.9 0.0 3.0 2 0 0 2 2 2 0 TPR repeat ASF1_hist_chap PF04729.8 KEZ42854.1 - 5.6e-67 224.1 0.0 7.4e-67 223.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 KEZ42854.1 - 1.8 6.4 26.2 2.2 6.1 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family BTV_NS2 PF04514.7 KEZ42854.1 - 4.6 6.0 9.5 6.4 5.5 6.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CorA PF01544.13 KEZ42856.1 - 1.5e-12 47.1 0.1 2.7e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RasGAP PF00616.14 KEZ42857.1 - 4.8e-55 186.2 0.2 3.1e-54 183.6 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KEZ42857.1 - 3.4e-28 98.0 4.7 3.4e-28 98.0 3.2 2.4 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 KEZ42857.1 - 0.25 11.7 7.9 3.7 7.9 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 KEZ42857.1 - 7.3 6.9 12.4 2.9 8.2 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Glyco_hydro_43 PF04616.9 KEZ42858.1 - 1.8e-15 56.8 3.3 2.5e-15 56.3 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pyocin_S PF06958.7 KEZ42858.1 - 0.014 15.7 0.1 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 S-type Pyocin IBR PF01485.16 KEZ42859.1 - 1.8e-22 78.9 44.7 7.3e-12 44.9 4.5 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KEZ42859.1 - 1.2e-06 28.4 6.5 1.2e-06 28.4 4.5 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ42859.1 - 4.2e-05 23.0 4.5 4.2e-05 23.0 3.1 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ42859.1 - 5.6e-05 22.8 6.3 5.6e-05 22.8 4.4 3.8 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KEZ42859.1 - 0.0018 17.9 7.9 0.0018 17.9 5.5 4.3 2 1 1 3 3 3 1 zinc-RING finger domain UN_NPL4 PF11543.3 KEZ42859.1 - 0.0083 16.3 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_UBOX PF13445.1 KEZ42859.1 - 2 8.2 24.9 0.029 14.1 1.3 3.7 3 1 0 3 3 3 0 RING-type zinc-finger Redoxin PF08534.5 KEZ42860.1 - 3.5e-14 52.5 0.0 4.4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KEZ42860.1 - 7.2e-05 22.4 0.0 9.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family XPG_I PF00867.13 KEZ42861.1 - 9.2e-26 89.7 0.0 1.8e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEZ42861.1 - 4.6e-25 87.8 0.0 8.6e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KEZ42861.1 - 0.00036 20.1 0.0 0.00062 19.3 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 KEZ42861.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_11 PF13414.1 KEZ42861.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 TPR repeat MAM33 PF02330.11 KEZ42862.1 - 3.5e-30 105.3 6.3 2.5e-29 102.5 4.3 1.9 1 1 0 1 1 1 1 Mitochondrial glycoprotein Oxysterol_BP PF01237.13 KEZ42863.1 - 9.6e-52 175.6 0.0 5e-41 140.3 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein CP2 PF04516.10 KEZ42864.1 - 1.5e-80 269.6 0.0 2.5e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor DUF2681 PF10883.3 KEZ42864.1 - 0.047 13.9 0.1 0.092 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Phage_G PF02306.10 KEZ42864.1 - 0.063 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Major spike protein (G protein) MFS_1 PF07690.11 KEZ42865.1 - 1.3e-27 96.4 30.1 1.3e-27 96.4 20.9 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 KEZ42865.1 - 0.0039 17.1 1.5 0.0039 17.1 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Sugar_tr PF00083.19 KEZ42865.1 - 0.01 14.4 13.7 0.0029 16.2 5.1 2.9 2 1 0 2 2 2 0 Sugar (and other) transporter TRI12 PF06609.8 KEZ42865.1 - 0.4 8.8 6.4 0.14 10.3 1.6 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF167 PF02594.11 KEZ42866.1 - 4.8e-17 61.6 0.4 8.2e-17 60.9 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Ribosomal_L37ae PF01780.14 KEZ42867.1 - 1.7e-37 127.1 5.6 1.9e-37 126.9 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 KEZ42867.1 - 0.046 13.1 2.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KEZ42867.1 - 0.072 12.9 3.4 0.13 12.1 2.3 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain C1_2 PF03107.11 KEZ42867.1 - 0.1 12.7 1.7 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 C1 domain zf-H2C2_2 PF13465.1 KEZ42867.1 - 0.19 12.0 1.2 3.5 8.0 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 KEZ42867.1 - 0.2 11.6 1.4 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain CarbpepA_inh PF02977.10 KEZ42867.1 - 0.98 9.0 3.5 1.6 8.3 1.4 1.9 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-C2H2 PF00096.21 KEZ42867.1 - 2 8.9 4.5 5.1 7.6 0.4 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2410 PF10307.4 KEZ42868.1 - 4.6e-77 257.8 0.0 6.2e-77 257.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Caprin-1_C PF12287.3 KEZ42868.1 - 4.9 6.4 14.8 11 5.2 10.2 1.5 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term W2 PF02020.13 KEZ42869.1 - 5.4e-18 64.7 3.2 1.3e-17 63.4 2.2 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KEZ42869.1 - 1e-07 31.0 12.2 0.00067 19.0 1.3 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEZ42869.1 - 3.7e-05 23.1 11.8 0.00083 18.8 0.8 3.1 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 KEZ42869.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain NTP_transferase PF00483.18 KEZ42869.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase HNH_2 PF13391.1 KEZ42870.1 - 6.1e-11 41.9 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Response_reg PF00072.19 KEZ42871.1 - 5e-22 78.0 0.0 1.1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 KEZ42871.1 - 3e-05 24.1 0.0 7.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF904 PF06005.7 KEZ42871.1 - 0.019 15.2 4.4 0.041 14.1 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 KEZ42871.1 - 0.043 13.3 3.4 0.11 12.0 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator RNA_pol_Rpb4 PF03874.11 KEZ42871.1 - 0.08 12.9 0.7 0.17 11.8 0.5 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF4613 PF15390.1 KEZ42871.1 - 0.095 10.8 2.4 0.14 10.3 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) ATG16 PF08614.6 KEZ42871.1 - 0.1 12.4 9.4 0.17 11.6 6.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Allexi_40kDa PF05549.6 KEZ42871.1 - 0.13 11.5 1.8 0.22 10.7 1.2 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein CENP-H PF05837.7 KEZ42871.1 - 0.13 12.4 8.8 0.046 13.8 3.8 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) KIAA1430 PF13879.1 KEZ42871.1 - 0.44 10.9 13.4 1.4 9.3 9.3 1.8 1 1 0 1 1 1 0 KIAA1430 homologue IncA PF04156.9 KEZ42871.1 - 0.5 9.9 8.5 0.78 9.2 5.9 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KEZ42871.1 - 1.1 9.5 6.2 1 9.7 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DNA_primase_S PF01896.14 KEZ42872.1 - 1.7e-52 177.1 0.1 2.6e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Tim17 PF02466.14 KEZ42873.1 - 4.3e-11 42.9 7.6 6.3e-11 42.4 5.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TauE PF01925.14 KEZ42873.1 - 0.078 12.4 7.5 0.11 11.9 5.2 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Gly-zipper_OmpA PF13436.1 KEZ42873.1 - 2.3 7.9 10.6 6.8 6.3 4.0 2.3 1 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain UCH PF00443.24 KEZ42874.1 - 5.7e-32 110.8 0.0 1.1e-31 109.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ42874.1 - 3.4e-11 43.1 0.1 0.00024 20.6 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KEZ42874.1 - 3.7e-07 29.4 0.2 0.0098 15.2 0.0 3.1 3 0 0 3 3 3 2 A repeated domain in UCH-protein PBP1_TM PF14812.1 KEZ42875.1 - 0.92 9.8 4.0 1.8 8.8 2.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tyrosinase PF00264.15 KEZ42877.1 - 1.5e-46 159.3 0.0 2.4e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase LSM PF01423.17 KEZ42878.1 - 2.3e-19 68.7 0.0 2.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Carb_anhydrase PF00194.16 KEZ42879.1 - 1.9e-17 63.1 0.1 9.4e-10 37.8 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase DPBB_1 PF03330.13 KEZ42880.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KEZ42880.1 - 0.054 13.1 1.0 0.11 12.2 0.3 1.7 2 0 0 2 2 2 0 Barwin family Xan_ur_permease PF00860.15 KEZ42881.1 - 2.4e-20 72.4 34.9 1.4e-18 66.6 21.8 2.9 2 1 0 2 2 2 1 Permease family Xan_ur_permease PF00860.15 KEZ42883.1 - 2.4e-59 200.7 34.2 1.4e-58 198.2 22.5 2.2 2 1 0 2 2 2 1 Permease family CorA PF01544.13 KEZ42883.1 - 0.21 10.5 0.7 0.46 9.4 0.5 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DOPA_dioxygen PF08883.6 KEZ42884.1 - 3.2e-28 97.8 0.0 4.8e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family GATase PF00117.23 KEZ42885.1 - 2.3e-36 125.0 0.0 3.7e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KEZ42885.1 - 1.8e-30 104.5 0.2 3.4e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KEZ42885.1 - 2.7e-10 39.5 0.0 3.9e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KEZ42885.1 - 2.5e-06 27.1 0.0 8.7e-06 25.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 KEZ42885.1 - 0.00036 19.2 0.1 0.0011 17.6 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 KEZ42885.1 - 0.00092 18.5 0.0 0.017 14.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 KEZ42885.1 - 0.0021 17.5 0.0 0.0049 16.3 0.0 1.6 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.16 KEZ42885.1 - 0.0065 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.14 KEZ42885.1 - 0.0085 15.1 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.14 KEZ42885.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 KEZ42885.1 - 0.03 13.7 0.0 0.079 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Methyltransf_23 PF13489.1 KEZ42886.1 - 2.5e-21 76.0 0.0 5.2e-21 75.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42886.1 - 9.7e-12 45.2 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42886.1 - 2.4e-10 40.9 0.0 3.9e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42886.1 - 8.5e-10 39.0 0.0 5.9e-09 36.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42886.1 - 2.3e-07 30.5 0.0 2.6e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ42886.1 - 1.5e-05 25.2 0.0 3.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ42886.1 - 5.3e-05 22.3 0.0 0.00011 21.3 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KEZ42886.1 - 0.00016 20.8 0.0 0.49 9.4 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KEZ42886.1 - 0.00075 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KEZ42886.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KEZ42886.1 - 0.029 13.4 0.0 0.061 12.3 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FmrO PF07091.6 KEZ42886.1 - 0.039 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_26 PF13659.1 KEZ42886.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KEZ42886.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Fungal_trans_2 PF11951.3 KEZ42888.1 - 7.3e-20 70.9 0.0 9.8e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ42888.1 - 1.3e-05 25.0 9.0 2.4e-05 24.1 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COQ7 PF03232.8 KEZ42888.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 EBP PF05241.7 KEZ42889.1 - 8.9e-62 207.5 8.6 1e-61 207.3 5.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein CFEM PF05730.6 KEZ42891.1 - 1.1e-14 54.0 10.1 1.8e-14 53.3 7.0 1.3 1 0 0 1 1 1 1 CFEM domain Defensin_2 PF01097.13 KEZ42891.1 - 0.0072 16.0 1.7 0.024 14.3 1.2 1.9 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.15 KEZ42891.1 - 0.01 15.8 1.8 0.01 15.8 1.3 1.9 2 0 0 2 2 2 0 Gamma-thionin family 7tm_1 PF00001.16 KEZ42893.1 - 0.019 14.0 0.3 0.029 13.5 0.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) MpPF26 PF07666.6 KEZ42893.1 - 0.02 14.7 0.3 0.059 13.2 0.0 1.7 1 1 1 2 2 2 0 M penetrans paralogue family 26 Yip1 PF04893.12 KEZ42893.1 - 0.051 13.0 3.7 0.073 12.5 2.5 1.2 1 0 0 1 1 1 0 Yip1 domain DUF1218 PF06749.7 KEZ42893.1 - 0.13 12.7 6.1 0.9 10.0 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) 7TM_GPCR_Srz PF10325.4 KEZ42893.1 - 0.13 11.3 2.0 0.25 10.4 0.3 1.8 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz DUF3995 PF13160.1 KEZ42893.1 - 0.78 9.7 7.3 0.085 12.9 0.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3995) DUF202 PF02656.10 KEZ42893.1 - 2.7 8.2 9.0 1.4 9.1 1.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF21 PF01595.15 KEZ42893.1 - 4 6.7 7.0 2.5 7.3 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF21 Acyl_transf_3 PF01757.17 KEZ42894.1 - 7.3e-19 67.7 28.6 9.6e-18 64.1 18.8 2.6 1 1 1 2 2 2 1 Acyltransferase family Glyco_hydro_7 PF00840.15 KEZ42896.1 - 1.4e-189 630.0 16.0 1.6e-189 629.7 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 E1-E2_ATPase PF00122.15 KEZ42897.1 - 4.1e-55 186.3 8.2 4.1e-55 186.3 5.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ42897.1 - 1.4e-31 109.4 2.0 1.4e-31 109.4 1.4 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ42897.1 - 2.3e-28 100.0 0.0 2.8e-27 96.5 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ42897.1 - 2e-16 59.7 0.0 3.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEZ42897.1 - 1.4e-15 56.5 0.0 1.4e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEZ42897.1 - 7.4e-13 49.0 0.0 2e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ42897.1 - 8.3e-06 25.5 1.6 5.1e-05 22.9 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Lipoprotein_21 PF14041.1 KEZ42899.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 LppP/LprE lipoprotein Glyco_hydro_10 PF00331.15 KEZ42900.1 - 8.2e-99 330.6 0.0 9.4e-99 330.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AstA PF04958.7 KEZ42900.1 - 0.093 11.1 0.3 0.15 10.4 0.2 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Peptidase_M3 PF01432.15 KEZ42901.1 - 4.3e-88 296.3 0.0 5.7e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Pro_CA PF00484.14 KEZ42901.1 - 5.4e-21 75.2 0.0 1.4e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 Carbonic anhydrase Imm42 PF15601.1 KEZ42901.1 - 0.027 13.8 0.0 6.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 42 tRNA-synt_2b PF00587.20 KEZ42902.1 - 2.2e-66 222.6 0.1 5.3e-66 221.4 0.2 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEZ42902.1 - 9.3e-21 73.5 0.2 4.8e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain TPT PF03151.11 KEZ42903.1 - 4.6e-18 65.3 12.5 4.6e-18 65.3 8.7 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEZ42903.1 - 1.8e-07 30.3 19.7 2.3e-07 30.0 13.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEZ42903.1 - 7e-06 26.0 29.7 1.2e-05 25.3 8.5 2.7 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 KEZ42903.1 - 0.018 15.2 27.2 0.094 12.9 5.0 2.8 3 0 0 3 3 3 0 Multidrug resistance efflux transporter Epimerase PF01370.16 KEZ42904.1 - 2.7e-57 193.9 0.0 3.4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEZ42904.1 - 7.9e-24 84.0 0.0 7.6e-23 80.8 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEZ42904.1 - 3.7e-21 75.2 0.1 2.3e-20 72.5 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KEZ42904.1 - 8.5e-21 73.8 0.0 1.1e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KEZ42904.1 - 3.1e-18 65.6 0.0 4.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEZ42904.1 - 7.7e-07 29.2 0.0 1.3e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEZ42904.1 - 0.0086 15.9 0.0 0.57 10.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.1 KEZ42905.1 - 3.7e-15 55.9 0.0 6.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ42905.1 - 1.2e-09 38.5 0.0 5.3e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ42905.1 - 1.3e-07 31.2 0.0 7.1e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ42905.1 - 3.4e-07 30.6 0.0 8.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ42905.1 - 1e-06 29.3 0.1 3e-05 24.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ42905.1 - 0.00039 19.5 0.0 0.00067 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 KEZ42905.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 KEZ42905.1 - 0.012 14.7 0.0 0.043 12.9 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KEZ42905.1 - 0.029 14.3 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KEZ42905.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ42905.1 - 0.071 13.4 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KEZ42905.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pep3_Vps18 PF05131.9 KEZ42906.1 - 1.3e-45 154.4 0.3 1.3e-45 154.4 0.2 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KEZ42906.1 - 2.5e-12 46.5 10.9 4.2e-09 36.1 0.1 3.8 2 2 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 KEZ42906.1 - 0.0021 17.7 0.4 0.0021 17.7 0.3 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ42906.1 - 0.0045 16.7 0.4 0.0045 16.7 0.3 2.0 2 0 0 2 2 2 1 Ring finger domain DUF1086 PF06461.6 KEZ42906.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Apc3 PF12895.2 KEZ42906.1 - 0.052 13.6 1.2 1 9.5 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-rbx1 PF12678.2 KEZ42906.1 - 0.097 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEZ42906.1 - 0.13 12.2 0.5 0.4 10.7 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 KEZ42906.1 - 0.15 12.1 0.1 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4 PF00097.20 KEZ42906.1 - 2.5 7.8 4.1 0.78 9.4 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_C PF00137.16 KEZ42907.1 - 4.6e-25 87.2 24.1 3.8e-16 58.7 6.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 KEZ42907.1 - 0.0083 15.5 0.6 4.3 6.8 0.0 2.6 2 0 0 2 2 2 2 T-cell surface glycoprotein CD3 zeta chain DUF3816 PF12822.2 KEZ42907.1 - 0.013 15.3 9.8 0.013 15.3 6.8 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3816) MerC PF03203.9 KEZ42907.1 - 5.5 7.3 11.4 3 8.2 0.1 3.1 2 1 1 3 3 3 0 MerC mercury resistance protein Asp PF00026.18 KEZ42908.1 - 3.2e-74 250.0 0.1 3.9e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ42908.1 - 1.4e-14 54.3 1.4 3e-14 53.2 0.2 2.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEZ42908.1 - 6.9e-08 32.8 0.9 0.00048 20.5 0.1 3.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KEZ42908.1 - 1.3e-05 24.8 0.0 3.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Pkinase PF00069.20 KEZ42909.1 - 1.7e-69 233.8 0.0 2.4e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42909.1 - 1.1e-48 165.5 0.0 1.9e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KEZ42909.1 - 2.2e-30 104.6 0.1 5.4e-30 103.4 0.0 1.7 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KEZ42909.1 - 3.4e-18 65.2 0.2 2.8e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEZ42909.1 - 2.8e-15 56.2 0.1 5.1e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KEZ42909.1 - 9.8e-14 51.6 0.1 1.7e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KEZ42909.1 - 3.1e-07 29.6 0.0 0.00031 19.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Relaxase PF03432.9 KEZ42909.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Kdo PF06293.9 KEZ42909.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_PNT PF02198.11 KEZ42909.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PDT PF00800.13 KEZ42910.1 - 1.3e-67 226.9 0.0 1.9e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 KEZ42910.1 - 0.0029 17.0 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 ACT domain Sulfotransfer_3 PF13469.1 KEZ42911.1 - 0.047 14.6 0.0 0.088 13.7 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Mhr1 PF12829.2 KEZ42912.1 - 3.1e-26 91.0 1.1 3.6e-26 90.8 0.2 1.6 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Ribosomal_S13 PF00416.17 KEZ42914.1 - 4.7e-40 136.3 1.4 5.6e-40 136.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KEZ42914.1 - 0.051 12.1 0.0 0.051 12.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PDEase_I PF00233.14 KEZ42915.1 - 6e-46 157.1 0.4 8.8e-43 146.7 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.24 KEZ42916.1 - 3.4e-73 246.0 0.0 7.5e-72 241.6 0.0 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ42916.1 - 5.2e-19 68.7 0.0 5.1e-09 35.9 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KEZ42916.1 - 7.5e-07 29.4 0.0 1.7e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 DUSP domain API5 PF05918.6 KEZ42916.1 - 0.084 11.3 0.4 0.17 10.3 0.3 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_S10 PF00450.17 KEZ42917.1 - 7.5e-131 437.1 2.0 9.2e-131 436.8 1.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KEZ42917.1 - 0.00016 21.6 0.0 0.0021 18.0 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Carbpep_Y_N PF05388.6 KEZ42917.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide NUDIX_2 PF13869.1 KEZ42918.1 - 3.5e-80 267.7 0.0 4.1e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 KEZ42919.1 - 2.5e-39 133.7 0.0 3.2e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 KEZ42920.1 - 5e-15 55.0 1.2 7.3e-15 54.5 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 KEZ42920.1 - 0.0056 16.3 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-BED PF02892.10 KEZ42920.1 - 0.089 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 BED zinc finger Peptidase_M16 PF00675.15 KEZ42921.1 - 3.4e-32 111.2 0.4 1.3e-31 109.4 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEZ42921.1 - 1.9e-28 99.4 0.0 1.3e-16 60.7 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain Dabb PF07876.7 KEZ42921.1 - 4.9e-23 81.3 0.0 1.6e-22 79.7 0.0 2.0 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain zf-CCHC PF00098.18 KEZ42922.1 - 0.00069 19.4 1.8 0.0011 18.7 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.9 KEZ42922.1 - 0.0073 14.4 8.5 0.011 13.8 5.9 1.2 1 0 0 1 1 1 1 CDC45-like protein zf-CCHC_4 PF14392.1 KEZ42922.1 - 0.02 14.5 0.3 0.036 13.7 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.7 KEZ42922.1 - 0.12 10.3 12.2 0.14 10.0 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family ETRAMP PF09716.5 KEZ42922.1 - 1.3 9.0 5.7 1.1 9.2 2.6 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SURF2 PF05477.6 KEZ42922.1 - 3.3 6.7 13.9 5.7 6.0 9.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4551 PF15087.1 KEZ42922.1 - 5.7 5.1 6.1 10 4.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Nop53 PF07767.6 KEZ42922.1 - 9.8 5.0 19.0 0.74 8.7 8.9 1.9 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF2346 PF09803.4 KEZ42923.1 - 0.00033 20.4 4.8 0.0011 18.8 3.4 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Transcrip_reg PF01709.15 KEZ42924.1 - 8.3e-48 162.5 0.3 9.5e-48 162.3 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator GSDH PF07995.6 KEZ42925.1 - 2.6e-08 33.3 0.2 7.7e-06 25.2 0.1 3.4 2 1 1 3 3 3 2 Glucose / Sorbosone dehydrogenase NHL PF01436.16 KEZ42925.1 - 1e-06 28.3 0.8 0.0048 16.7 0.0 4.3 3 1 1 4 4 4 1 NHL repeat B9-C2 PF07162.6 KEZ42925.1 - 0.057 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein RCC1_2 PF13540.1 KEZ42925.1 - 5.8 6.6 10.7 1.7 8.3 0.2 4.0 4 1 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat HEAT_2 PF13646.1 KEZ42926.1 - 3e-12 46.6 9.7 0.0079 16.4 0.0 7.1 6 1 1 7 7 7 4 HEAT repeats HEAT PF02985.17 KEZ42926.1 - 1.3e-10 40.4 16.7 0.21 11.7 0.0 9.2 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 KEZ42926.1 - 3.4e-08 33.7 0.1 0.013 15.8 0.0 4.1 3 0 0 3 3 3 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KEZ42926.1 - 0.00071 18.0 1.2 1.4 7.0 0.0 4.4 4 1 0 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.3 KEZ42926.1 - 0.01 15.1 9.6 23 4.2 0.0 6.0 5 1 1 6 6 6 0 CLASP N terminal GATA PF00320.22 KEZ42926.1 - 0.16 11.3 0.2 0.4 10.0 0.1 1.7 1 0 0 1 1 1 0 GATA zinc finger RRM_1 PF00076.17 KEZ42927.1 - 9.8e-05 21.9 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ42927.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MoaC PF01967.16 KEZ42929.1 - 2.6e-53 179.3 3.9 4e-53 178.7 2.3 1.6 2 0 0 2 2 2 1 MoaC family Mob_synth_C PF06463.8 KEZ42929.1 - 3.2e-34 117.3 0.1 1.2e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KEZ42929.1 - 2.3e-20 73.4 0.1 4.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KEZ42929.1 - 0.00015 21.8 0.0 0.0004 20.5 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KEZ42929.1 - 0.00057 19.9 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain FYVE PF01363.16 KEZ42930.1 - 1.2e-15 57.0 8.0 2e-15 56.4 5.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger Innate_immun PF12782.2 KEZ42930.1 - 0.03 13.5 6.1 0.21 10.7 1.3 2.1 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family zf-AN1 PF01428.11 KEZ42930.1 - 1.1 9.2 13.2 0.87 9.5 6.2 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger CDK2AP PF09806.4 KEZ42930.1 - 2.6 8.2 15.6 4.6 7.4 6.0 2.5 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein CfAFP PF05264.6 KEZ42930.1 - 3.1 7.5 9.0 6.1 6.6 2.4 2.4 2 0 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) ELO PF01151.13 KEZ42931.1 - 4.3e-84 281.7 5.8 5.3e-84 281.4 4.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family GMC_oxred_N PF00732.14 KEZ42932.1 - 3.4e-46 157.7 0.1 5.4e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ42932.1 - 8.5e-26 90.9 0.4 2.5e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KEZ42932.1 - 1.1e-11 44.2 1.2 4e-11 42.4 0.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ42932.1 - 4.6e-07 29.0 0.1 3e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ42932.1 - 2.1e-06 27.7 0.2 4.8e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ42932.1 - 2.3e-06 27.5 0.2 6.3e-06 26.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEZ42932.1 - 1.9e-05 23.8 0.0 3.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEZ42932.1 - 3.6e-05 22.9 0.4 0.0019 17.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEZ42932.1 - 0.00032 19.2 0.1 0.00054 18.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KEZ42932.1 - 0.0046 16.0 0.3 0.0073 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ42932.1 - 0.058 12.3 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KEZ42932.1 - 0.097 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A PH PF00169.24 KEZ42933.1 - 3.8e-05 23.8 0.0 0.00015 21.9 0.0 2.1 1 1 0 1 1 1 1 PH domain GRAM PF02893.15 KEZ42933.1 - 0.0025 17.2 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF2428 PF10350.4 KEZ42934.1 - 7.1e-56 189.0 0.0 1.2e-55 188.3 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KEZ42934.1 - 2.8e-09 36.2 8.8 0.11 12.6 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KEZ42934.1 - 2.2e-06 27.8 7.0 0.27 11.5 0.1 5.3 5 0 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 KEZ42934.1 - 1.5e-05 25.3 7.7 2.9 8.4 0.0 6.2 4 1 1 5 5 5 2 HEAT-like repeat NinB PF05772.7 KEZ42934.1 - 0.12 12.0 0.0 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 NinB protein Ribosomal_L1 PF00687.16 KEZ42935.1 - 1.3e-51 175.1 0.8 1.5e-51 174.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 KEZ42935.1 - 0.072 11.5 0.1 0.099 11.0 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DEK_C PF08766.6 KEZ42935.1 - 0.5 10.1 3.8 0.52 10.1 0.0 2.6 3 0 0 3 3 3 0 DEK C terminal domain PAN_1 PF00024.21 KEZ42936.1 - 8e-07 28.7 0.0 2.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 KEZ42936.1 - 0.00012 21.6 0.3 0.00021 20.9 0.2 1.3 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 KEZ42936.1 - 0.044 13.3 0.3 0.094 12.3 0.2 1.6 1 0 0 1 1 1 0 PAN-like domain Glyco_transf_22 PF03901.12 KEZ42937.1 - 2.7e-59 201.2 23.5 3.3e-59 200.9 16.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.14 KEZ42938.1 - 3.5e-39 132.7 0.9 5.9e-39 131.9 0.6 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KEZ42938.1 - 2e-19 69.4 0.1 5e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KEZ42938.1 - 0.0061 16.5 1.2 0.0081 16.1 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) Arf PF00025.16 KEZ42939.1 - 1.1e-59 200.5 0.2 3.9e-58 195.5 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KEZ42939.1 - 3.8e-08 32.4 0.1 9e-08 31.1 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 KEZ42939.1 - 7.3e-08 31.9 0.0 9.5e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KEZ42939.1 - 4.2e-06 26.0 0.0 5.3e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEZ42939.1 - 1e-05 24.8 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KEZ42939.1 - 0.00017 22.0 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEZ42939.1 - 0.00034 20.0 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 KEZ42939.1 - 0.0038 16.0 0.2 0.0074 15.0 0.1 1.4 1 1 0 1 1 1 1 ArgK protein DUF3986 PF13143.1 KEZ42939.1 - 0.082 13.3 0.2 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) TRP PF06011.7 KEZ42940.1 - 7.2e-30 103.9 14.7 1.9e-29 102.5 10.2 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Glyco_hydro_16 PF00722.16 KEZ42942.1 - 3e-14 52.7 0.0 5.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4348 PF14254.1 KEZ42942.1 - 0.099 11.7 1.0 0.16 11.0 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) Fungal_trans PF04082.13 KEZ42943.1 - 3.6e-16 58.8 2.1 6.1e-16 58.0 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KEZ42943.1 - 2.7e-08 33.6 12.5 1.7e-05 24.8 4.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEZ42943.1 - 6.4e-05 22.9 13.0 0.0041 17.3 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ42943.1 - 0.00019 21.5 14.7 0.035 14.4 4.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type RasGEF PF00617.14 KEZ42944.1 - 3.2e-64 216.1 0.1 5.6e-64 215.3 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEZ42944.1 - 1.9e-28 98.6 0.3 4.7e-28 97.3 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KEZ42944.1 - 1.3e-16 59.7 0.1 2.6e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ42944.1 - 3.7e-14 52.0 0.2 7.5e-14 51.0 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KEZ42944.1 - 8.6e-14 50.7 0.2 1.8e-13 49.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KEZ42944.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 WW domain SCA7 PF08313.7 KEZ42945.1 - 2.5e-34 116.7 0.4 6.6e-34 115.3 0.3 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF3245 PF11595.3 KEZ42945.1 - 1.7 8.9 25.7 0.3 11.3 13.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3245) Acyltransferase PF01553.16 KEZ42946.1 - 2.1e-12 46.6 0.0 3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase zf-C3HC4_2 PF13923.1 KEZ42947.1 - 8.3e-10 38.5 19.2 9.9e-06 25.4 5.3 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ42947.1 - 5.1e-07 29.4 14.2 0.00024 20.8 4.9 2.6 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.7 KEZ42947.1 - 1.5e-06 27.6 0.8 1.5e-06 27.6 0.5 2.8 2 1 1 3 3 3 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KEZ42947.1 - 1.5e-05 24.6 2.6 1.5e-05 24.6 1.8 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KEZ42947.1 - 1.7e-05 24.3 14.3 0.00023 20.7 4.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ42947.1 - 2.2e-05 24.1 13.9 5.4e-05 22.8 3.9 2.8 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KEZ42947.1 - 0.00023 20.9 14.9 0.0054 16.5 5.0 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING Atg14 PF10186.4 KEZ42947.1 - 0.00033 19.7 0.9 0.00053 19.0 0.6 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 KEZ42947.1 - 0.27 10.1 3.3 0.39 9.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FYVE PF01363.16 KEZ42947.1 - 1 9.3 12.6 2.5 8.0 4.7 2.9 2 1 1 3 3 3 0 FYVE zinc finger Pkinase PF00069.20 KEZ42948.1 - 1.1e-76 257.4 0.0 1.3e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ42948.1 - 1.2e-37 129.3 0.0 1.7e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ42948.1 - 0.0063 15.5 0.0 0.018 13.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ42948.1 - 0.032 13.3 0.1 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEZ42948.1 - 0.063 13.0 0.9 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Septin PF00735.13 KEZ42949.1 - 2.1e-10 40.0 1.0 3.6e-07 29.4 0.0 2.9 2 1 1 3 3 3 2 Septin Miro PF08477.8 KEZ42949.1 - 0.00099 19.6 0.1 0.038 14.4 0.1 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_19 PF13245.1 KEZ42949.1 - 0.0036 17.0 2.2 0.017 14.8 0.4 2.4 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 KEZ42949.1 - 0.0046 16.9 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEZ42949.1 - 0.0051 16.2 0.0 0.057 12.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KEZ42949.1 - 0.0084 16.1 0.2 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KEZ42949.1 - 0.043 13.2 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 KEZ42949.1 - 0.052 13.7 0.1 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KEZ42949.1 - 0.058 12.3 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MobB PF03205.9 KEZ42949.1 - 0.12 12.1 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KEZ42949.1 - 0.12 11.4 0.8 3.6 6.7 0.3 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KEZ42949.1 - 0.14 12.9 0.0 0.73 10.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 KEZ42949.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.8 KEZ42949.1 - 0.16 10.6 0.6 0.23 10.1 0.4 1.1 1 0 0 1 1 1 0 TIP49 C-terminus PAP_central PF04928.12 KEZ42950.1 - 2.9e-102 340.8 0.0 3.9e-102 340.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KEZ42950.1 - 5.1e-44 149.5 0.0 1.4e-43 148.1 0.0 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KEZ42950.1 - 6.5e-06 26.3 0.0 1.6e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain Tubulin_3 PF14881.1 KEZ42951.1 - 4.3e-51 172.9 0.0 1.7e-50 171.0 0.0 1.9 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KEZ42951.1 - 4.7e-38 129.7 0.0 9.2e-38 128.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 KEZ42951.1 - 2.7e-06 27.3 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Aminotran_3 PF00202.16 KEZ42952.1 - 7.9e-79 264.9 0.0 9.5e-79 264.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KEZ42952.1 - 0.051 12.5 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Fork_head PF00250.13 KEZ42953.1 - 3e-34 116.9 0.1 5.3e-34 116.1 0.1 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KEZ42953.1 - 2.8e-09 36.9 0.0 5.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain CLU PF13236.1 KEZ42954.1 - 3.4e-78 262.0 0.0 5.6e-78 261.3 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 KEZ42954.1 - 8.7e-52 175.4 0.8 8.1e-51 172.3 0.0 2.7 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 KEZ42954.1 - 2.1e-24 85.4 0.7 4.4e-24 84.4 0.5 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 KEZ42954.1 - 7.4e-22 77.0 5.0 4.2e-11 42.6 0.0 3.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ42954.1 - 1.9e-18 65.7 3.3 5.4e-05 22.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ42954.1 - 1.1e-06 28.1 2.4 0.0077 15.8 0.1 3.7 2 1 3 5 5 5 4 TPR repeat TPR_2 PF07719.12 KEZ42954.1 - 0.00081 19.1 3.3 0.89 9.6 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ42954.1 - 0.055 13.2 0.6 6.3 6.8 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat INCENP_N PF12178.3 KEZ42954.1 - 1.9 8.1 4.5 3.1 7.4 0.0 2.9 3 0 0 3 3 3 0 Chromosome passenger complex (CPC) protein INCENP N terminal Ferric_reduct PF01794.14 KEZ42955.1 - 2.2e-21 76.2 12.2 6.4e-21 74.7 8.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEZ42955.1 - 2.1e-17 63.4 0.0 6.9e-10 39.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEZ42955.1 - 1.3e-15 57.1 0.0 6.8e-15 54.8 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain SPOUT_MTase PF02590.12 KEZ42955.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Yippee-Mis18 PF03226.9 KEZ42956.1 - 8.5e-23 80.2 0.9 9.8e-23 80.0 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 KEZ42956.1 - 0.016 15.2 2.2 0.033 14.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 KEZ42956.1 - 0.026 14.3 2.1 0.061 13.1 1.5 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 KEZ42956.1 - 0.035 14.0 1.1 2.1 8.3 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF3268 PF11672.3 KEZ42956.1 - 0.041 13.9 1.1 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) HNH_5 PF14279.1 KEZ42956.1 - 0.062 13.3 1.4 2.4 8.2 0.0 2.2 1 1 0 2 2 2 0 HNH endonuclease zf-CHY PF05495.7 KEZ42956.1 - 0.1 12.7 1.7 9 6.5 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger RNA_POL_M_15KD PF02150.11 KEZ42956.1 - 0.22 11.2 2.0 15 5.3 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Nuc_sug_transp PF04142.10 KEZ42957.1 - 5.5e-09 35.4 1.4 5.5e-09 35.4 0.9 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 KEZ42957.1 - 3.7e-06 26.9 26.8 0.00098 19.1 4.9 3.2 2 1 1 3 3 3 3 EamA-like transporter family TPT PF03151.11 KEZ42957.1 - 0.0036 16.9 21.1 0.0052 16.4 5.9 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family PDR_assoc PF08370.6 KEZ42957.1 - 0.5 9.9 5.2 13 5.4 0.3 3.2 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF423 PF04241.10 KEZ42957.1 - 1.8 8.5 6.4 23 4.9 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF2985 PF11204.3 KEZ42958.1 - 5.6e-39 131.7 2.0 5.6e-39 131.7 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) ADH_N PF08240.7 KEZ42959.1 - 1.3e-29 102.0 0.5 1.3e-29 102.0 0.4 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ42959.1 - 4.9e-19 68.1 0.0 8.1e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KEZ42959.1 - 0.0025 17.4 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KEZ42959.1 - 0.0029 18.4 0.0 0.0053 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C2H2_4 PF13894.1 KEZ42960.1 - 1.5e-05 24.9 13.2 0.006 16.8 1.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ42960.1 - 3.7e-05 23.8 11.4 0.032 14.5 0.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 KEZ42960.1 - 0.076 13.1 4.8 0.19 11.8 0.2 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KEZ42960.1 - 0.17 12.2 9.0 0.86 10.0 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Peptidase_C2 PF00648.16 KEZ42961.1 - 1.1e-18 67.3 0.0 2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 KEZ42961.1 - 4.3e-17 62.1 0.2 7e-10 38.7 0.0 3.5 3 1 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.13 KEZ42961.1 - 4.9e-05 23.1 0.4 8.2e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 KEZ42962.1 - 9e-56 185.5 0.5 1.4e-19 69.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SAM_2 PF07647.12 KEZ42963.1 - 2.1e-10 40.3 0.1 4.2e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KEZ42963.1 - 1.3e-05 25.2 0.2 3.1e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KEZ42963.1 - 0.14 12.1 0.3 0.36 10.7 0.1 1.7 2 0 0 2 2 2 0 IGR protein motif TPR_11 PF13414.1 KEZ42964.1 - 4.3e-19 67.9 16.9 9.1e-05 22.0 1.3 7.2 7 0 0 7 7 7 4 TPR repeat TPR_16 PF13432.1 KEZ42964.1 - 4.2e-15 55.9 32.2 0.0041 17.7 0.0 10.3 7 3 3 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ42964.1 - 5.5e-08 33.0 24.2 0.086 13.1 0.6 9.6 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ42964.1 - 1.9e-07 31.1 15.0 0.026 14.6 0.7 7.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ42964.1 - 3.4e-07 29.5 18.4 0.09 12.4 0.1 7.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ42964.1 - 4e-07 29.7 8.8 0.075 13.2 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ42964.1 - 5e-07 29.7 28.0 0.055 14.1 0.1 10.5 9 3 3 12 12 12 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ42964.1 - 1e-06 28.5 26.6 0.0002 21.2 0.6 8.1 8 2 1 9 9 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ42964.1 - 5.9e-06 25.6 3.8 1 9.3 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ42964.1 - 0.0004 20.0 37.9 0.14 12.1 0.1 11.4 15 0 0 15 15 12 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ42964.1 - 0.0019 17.9 11.5 0.17 11.7 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KEZ42964.1 - 0.033 14.4 1.3 2.9 8.1 0.0 3.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.1 KEZ42964.1 - 0.06 13.3 9.8 0.69 9.9 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEZ42964.1 - 0.094 12.6 0.7 4 7.3 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 KEZ42964.1 - 0.4 10.5 11.8 1.6 8.7 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ42964.1 - 9.9 6.8 14.7 20 5.9 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat ABC_tran PF00005.22 KEZ42966.1 - 1.8e-46 157.8 3.7 6.6e-23 81.5 0.0 3.4 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 KEZ42966.1 - 1.5e-20 72.8 7.5 1.5e-20 72.8 5.2 3.7 5 0 0 5 5 5 1 ABC transporter AAA_21 PF13304.1 KEZ42966.1 - 4.5e-18 66.2 0.1 3.2e-05 24.0 0.0 4.5 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 KEZ42966.1 - 3.3e-10 39.5 1.1 0.015 14.4 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEZ42966.1 - 6.4e-10 39.9 0.2 0.00071 20.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KEZ42966.1 - 1.6e-06 27.5 0.3 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KEZ42966.1 - 3.1e-06 27.6 0.0 0.012 16.0 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KEZ42966.1 - 4.6e-06 26.5 0.0 0.018 14.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ42966.1 - 8.3e-06 25.0 0.1 0.0074 15.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEZ42966.1 - 1.1e-05 25.7 3.5 0.044 14.1 0.0 3.4 5 0 0 5 5 2 2 AAA domain AAA_15 PF13175.1 KEZ42966.1 - 1.1e-05 24.6 6.2 0.24 10.4 0.0 4.6 4 2 1 5 5 5 2 AAA ATPase domain AAA_33 PF13671.1 KEZ42966.1 - 1.4e-05 25.0 0.1 0.083 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KEZ42966.1 - 2.5e-05 23.9 0.1 0.17 11.6 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KEZ42966.1 - 4.4e-05 23.5 3.9 0.0046 16.9 0.0 3.3 4 0 0 4 4 3 1 AAA ATPase domain ArgK PF03308.11 KEZ42966.1 - 0.00011 21.1 0.2 0.31 9.7 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KEZ42966.1 - 0.00012 22.1 0.2 1.3 9.1 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KEZ42966.1 - 0.00024 20.9 0.0 1.3 8.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 KEZ42966.1 - 0.00026 21.0 0.8 0.25 11.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEZ42966.1 - 0.00028 21.1 0.0 0.57 10.3 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KEZ42966.1 - 0.00054 19.5 0.4 0.28 10.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 KEZ42966.1 - 0.00096 19.5 0.1 0.037 14.3 0.0 4.8 4 1 1 5 5 4 2 AAA domain SbcCD_C PF13558.1 KEZ42966.1 - 0.002 18.0 0.2 1.9 8.4 0.1 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 KEZ42966.1 - 0.0023 17.5 0.3 3.1 7.4 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 KEZ42966.1 - 0.0031 16.9 0.0 2.5 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KEZ42966.1 - 0.0031 17.0 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 KEZ42966.1 - 0.0064 16.3 10.1 0.26 11.1 0.1 4.2 4 1 0 4 4 4 1 Dynamin family cobW PF02492.14 KEZ42966.1 - 0.0065 15.9 0.6 2.2 7.6 0.4 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KEZ42966.1 - 0.0073 16.0 0.8 1.1 8.9 0.0 3.0 3 0 0 3 3 2 1 NTPase RNA_helicase PF00910.17 KEZ42966.1 - 0.0093 16.1 0.1 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KEZ42966.1 - 0.01 15.2 1.0 4 6.8 0.1 3.5 4 0 0 4 4 3 0 AAA-like domain AAA_24 PF13479.1 KEZ42966.1 - 0.022 14.3 0.1 3.4 7.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KEZ42966.1 - 0.026 13.3 0.0 4.3 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 KEZ42966.1 - 0.034 13.8 0.5 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 KEZ42966.1 - 0.037 13.5 0.0 5.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 KEZ42966.1 - 0.043 12.9 1.5 16 4.5 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.22 KEZ42966.1 - 0.046 13.1 1.3 11 5.3 0.0 3.0 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Sigma54_activ_2 PF14532.1 KEZ42966.1 - 0.066 13.2 0.1 5.5 7.0 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain SRP54 PF00448.17 KEZ42966.1 - 0.21 11.0 3.2 3.6 6.9 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Tubulin PF00091.20 KEZ42967.1 - 6.4e-65 218.9 0.0 1.2e-64 218.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEZ42967.1 - 2e-48 163.5 0.0 3.4e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KEZ42967.1 - 0.0045 17.0 0.0 0.023 14.7 0.0 2.1 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KEZ42967.1 - 0.0049 16.3 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L6 PF00347.18 KEZ42968.1 - 7.9e-22 77.5 0.1 6.7e-11 42.5 0.0 3.3 2 2 1 3 3 3 2 Ribosomal protein L6 Aha1_N PF09229.6 KEZ42970.1 - 4.5e-37 126.9 0.4 6.8e-37 126.3 0.3 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KEZ42970.1 - 1.8e-17 63.5 0.5 3.9e-17 62.4 0.4 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein zf-DHHC PF01529.15 KEZ42971.1 - 1.4e-31 109.2 5.7 1.4e-31 109.2 4.0 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase LRV_FeS PF05484.6 KEZ42971.1 - 0.52 9.9 5.0 1.2 8.7 3.4 1.6 1 0 0 1 1 1 0 LRV protein FeS4 cluster Adeno_E1A PF02703.9 KEZ42971.1 - 1.4 8.3 5.2 2 7.8 3.6 1.1 1 0 0 1 1 1 0 Early E1A protein RRN9 PF10680.4 KEZ42971.1 - 6.1 6.6 6.1 0.52 10.0 0.4 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Rap1_C PF11626.3 KEZ42972.1 - 1.4e-23 82.5 1.7 6.2e-22 77.3 0.0 2.9 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KEZ42972.1 - 3.4e-18 65.2 5.3 1.9e-12 46.7 0.3 2.5 2 0 0 2 2 2 2 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KEZ42972.1 - 9.2e-09 35.8 7.1 0.0011 19.4 0.4 3.5 3 0 0 3 3 3 2 Rap1, DNA-binding BRCT PF00533.21 KEZ42972.1 - 0.0037 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain tRNA-synt_1c PF00749.16 KEZ42972.1 - 0.016 13.8 5.0 0.094 11.3 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain CN_hydrolase PF00795.17 KEZ42973.1 - 2.2e-26 92.3 0.0 2.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase p450 PF00067.17 KEZ42974.1 - 7e-40 136.9 0.0 4.3e-38 131.0 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 HLH PF00010.21 KEZ42975.1 - 7.7e-15 54.3 0.0 1.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.8 KEZ42975.1 - 1 9.1 28.2 0.24 11.2 16.6 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CytochromB561_N PF09786.4 KEZ42975.1 - 6.4 5.0 12.7 11 4.2 8.8 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF605 PF04652.11 KEZ42975.1 - 7.2 5.8 41.2 3.8 6.8 22.1 2.4 2 0 0 2 2 2 0 Vta1 like Peptidase_M24 PF00557.19 KEZ42976.1 - 2.1e-44 151.5 0.0 2.9e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KEZ42976.1 - 3.1e-32 110.7 0.0 2e-31 108.1 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 KEZ42977.1 - 8.8e-42 141.8 0.0 1.9e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KEZ42977.1 - 1.2e-21 76.0 0.5 2.6e-21 75.0 0.3 1.6 1 0 0 1 1 1 1 DBF zinc finger HNH PF01844.18 KEZ42977.1 - 0.097 12.5 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease BRCT PF00533.21 KEZ42977.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain bZIP_1 PF00170.16 KEZ42978.1 - 0.0007 19.5 2.7 0.0007 19.5 1.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor APG12 PF04110.8 KEZ42979.1 - 1.8e-27 95.3 0.0 2.6e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KEZ42979.1 - 0.0027 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 KEZ42980.1 - 5.2e-102 340.4 0.2 6.1e-102 340.2 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KEZ42980.1 - 9.2e-10 38.1 0.8 1.3e-09 37.6 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase UQ_con PF00179.21 KEZ42981.1 - 1.6e-33 115.0 0.0 2.7e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HNH_2 PF13391.1 KEZ42981.1 - 0.061 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease ChW PF07538.6 KEZ42981.1 - 0.075 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Clostridial hydrophobic W CorA PF01544.13 KEZ42982.1 - 3.4e-06 26.3 1.9 1.7e-05 24.0 0.4 2.4 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF791 PF05631.9 KEZ42983.1 - 2.8e-68 230.2 3.2 3.6e-68 229.8 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KEZ42983.1 - 5.2e-23 81.3 25.6 5.2e-23 81.3 17.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ42983.1 - 0.013 15.2 0.8 0.7 9.7 0.0 3.0 3 0 0 3 3 3 0 MFS_1 like family SIR2 PF02146.12 KEZ42984.1 - 2.5e-33 115.3 0.0 4.9e-33 114.3 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Peripla_BP_4 PF13407.1 KEZ42984.1 - 0.0054 16.1 0.0 0.0078 15.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain PhnA_Zn_Ribbon PF08274.7 KEZ42984.1 - 0.022 14.5 0.0 0.07 12.9 0.0 1.8 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Soyouz_module PF14313.1 KEZ42984.1 - 0.064 12.8 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Glyco_transf_4 PF13439.1 KEZ42984.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_hydro_16 PF00722.16 KEZ42985.1 - 1.9e-42 144.6 1.4 3.4e-42 143.8 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pex14_N PF04695.8 KEZ42985.1 - 0.042 13.9 2.8 0.073 13.1 2.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAGE_N PF12440.3 KEZ42985.1 - 0.32 11.3 16.9 1.1 9.6 11.7 1.9 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal MR_MLE_C PF13378.1 KEZ42986.1 - 1.6e-19 69.9 0.0 4.4e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KEZ42986.1 - 5.4e-14 52.4 0.2 4e-13 49.6 0.0 2.3 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KEZ42986.1 - 0.00091 19.2 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KEZ42986.1 - 0.0014 17.5 0.0 0.0038 16.2 0.0 1.6 1 1 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Pectate_lyase_3 PF12708.2 KEZ42987.1 - 1.1e-82 277.5 9.6 5.1e-66 223.0 2.7 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KEZ42987.1 - 3e-06 26.5 1.8 0.017 14.5 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase LysM PF01476.15 KEZ42987.1 - 0.0052 16.6 0.0 0.72 9.7 0.0 3.0 3 0 0 3 3 3 1 LysM domain Glyco_hydro_18 PF00704.23 KEZ42988.1 - 2.1e-69 234.5 0.2 3.1e-69 234.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEZ42988.1 - 2.7e-08 33.6 3.3 2.7e-08 33.6 2.3 3.9 4 0 0 4 4 4 1 Chitin recognition protein Rad10 PF03834.9 KEZ42989.1 - 4.3e-30 103.2 0.0 6.6e-30 102.6 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KEZ42989.1 - 6.6e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Glyco_transf_64 PF09258.5 KEZ42989.1 - 0.07 12.2 0.1 0.55 9.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain Glyco_hydro_47 PF01532.15 KEZ42990.1 - 3.9e-129 431.2 0.0 4.5e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 VIT1 PF01988.14 KEZ42991.1 - 1.9e-57 194.2 2.3 2.2e-57 193.9 1.6 1.1 1 0 0 1 1 1 1 VIT family Lactamase_B_2 PF12706.2 KEZ42992.1 - 3.6e-41 140.8 0.0 5.2e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KEZ42992.1 - 8.1e-12 45.1 0.0 3.2e-11 43.1 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KEZ42992.1 - 0.00021 21.0 1.6 0.0017 18.0 0.4 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Ndc80_HEC PF03801.8 KEZ42993.1 - 2.8e-63 212.1 0.2 4.6e-63 211.4 0.1 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.16 KEZ42993.1 - 2.2e-05 24.0 44.2 0.0052 16.2 11.2 3.5 3 1 1 4 4 4 2 Intermediate filament protein ATG16 PF08614.6 KEZ42993.1 - 0.003 17.4 34.0 0.43 10.3 0.9 4.1 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) ERM PF00769.14 KEZ42993.1 - 0.0043 16.6 16.1 0.0043 16.6 11.2 3.3 2 1 1 3 3 3 1 Ezrin/radixin/moesin family WASH_WAHD PF11945.3 KEZ42993.1 - 0.0048 16.2 2.1 0.0048 16.2 1.4 1.8 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF1664 PF07889.7 KEZ42993.1 - 0.0051 16.5 1.1 0.0051 16.5 0.8 5.2 3 2 2 5 5 5 1 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 KEZ42993.1 - 0.016 15.0 51.7 0.078 12.8 13.6 4.2 2 2 1 3 3 3 0 Tropomyosin like NPV_P10 PF05531.7 KEZ42993.1 - 0.053 13.7 12.7 7.3 6.9 0.6 4.8 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 KEZ42993.1 - 0.15 11.8 42.1 1.7 8.3 11.0 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF720 PF05302.6 KEZ42993.1 - 0.28 10.9 7.4 0.082 12.6 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF720) FliJ PF02050.11 KEZ42993.1 - 0.39 10.7 30.3 0.11 12.4 2.4 3.9 3 1 1 4 4 4 0 Flagellar FliJ protein Spc7 PF08317.6 KEZ42993.1 - 0.46 9.1 39.0 0.4 9.2 10.6 3.6 2 2 0 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KEZ42993.1 - 0.75 8.9 6.1 0.12 11.5 0.4 2.2 2 2 0 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 KEZ42993.1 - 1.4 8.8 33.1 1.3 8.8 2.0 4.4 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.15 KEZ42993.1 - 3 6.8 49.0 0.78 8.7 12.4 3.5 2 1 1 3 3 3 0 Tropomyosin MtrG PF04210.8 KEZ42993.1 - 4.2 7.1 9.8 3.9 7.2 0.1 3.8 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G CCDC155 PF14662.1 KEZ42993.1 - 7.4 6.1 37.3 0.34 10.4 14.9 3.2 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 Strep_SA_rep PF06696.6 KEZ42993.1 - 7.5 6.4 8.2 15 5.4 0.1 3.9 3 1 0 3 3 3 0 Streptococcal surface antigen repeat GAS PF13851.1 KEZ42993.1 - 8.4 5.5 47.9 0.011 14.9 11.3 3.5 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KEZ42993.1 - 9.1 5.2 42.3 1.7 7.6 9.5 3.3 2 1 1 3 3 3 0 Autophagy protein Apg6 Pex14_N PF04695.8 KEZ42994.1 - 5.7e-42 142.9 8.5 2e-41 141.2 0.0 2.5 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 KEZ42994.1 - 8.7e-05 22.6 1.5 8.7e-05 22.6 1.0 1.8 2 0 0 2 2 2 1 Zinc finger-containing protein ERM PF00769.14 KEZ42994.1 - 0.0015 18.1 7.6 0.0023 17.5 5.3 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF848 PF05852.6 KEZ42994.1 - 0.0064 16.3 8.7 0.012 15.4 6.1 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) HLH PF00010.21 KEZ42994.1 - 0.023 14.4 3.5 6.9 6.4 2.4 3.2 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain Syntaxin PF00804.20 KEZ42994.1 - 0.029 14.5 7.7 0.055 13.6 5.4 1.5 1 0 0 1 1 1 0 Syntaxin DUF1664 PF07889.7 KEZ42994.1 - 0.075 12.8 2.1 0.17 11.6 1.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CR6_interact PF10147.4 KEZ42994.1 - 0.081 12.2 3.4 0.073 12.3 1.5 1.5 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Prominin PF05478.6 KEZ42994.1 - 0.083 10.4 2.4 0.11 10.0 1.6 1.1 1 0 0 1 1 1 0 Prominin FUSC PF04632.7 KEZ42994.1 - 0.15 10.4 2.7 0.22 9.8 1.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.7 KEZ42994.1 - 0.24 11.2 8.4 1.6 8.5 0.6 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KEZ42994.1 - 0.27 9.8 6.9 0.41 9.2 4.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4164 PF13747.1 KEZ42994.1 - 0.28 11.3 16.9 0.29 11.2 7.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) AAA_13 PF13166.1 KEZ42994.1 - 0.29 9.5 8.0 0.38 9.1 5.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KEZ42994.1 - 0.29 8.4 11.1 0.38 8.0 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.6 KEZ42994.1 - 0.37 10.7 2.1 0.63 9.9 0.5 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) tRNA-synt_His PF13393.1 KEZ42994.1 - 0.39 9.7 4.5 2.3 7.1 0.0 2.3 1 1 1 2 2 2 0 Histidyl-tRNA synthetase IFT57 PF10498.4 KEZ42994.1 - 0.89 8.2 7.5 1.3 7.6 5.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 KEZ42994.1 - 1.1 8.7 13.8 3.6 7.1 9.8 1.5 1 1 0 1 1 1 0 IncA protein DUF148 PF02520.12 KEZ42994.1 - 1.1 9.0 5.4 2.8 7.7 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 SlyX PF04102.7 KEZ42994.1 - 1.7 9.0 8.7 4.2 7.8 2.1 2.9 1 1 2 3 3 3 0 SlyX V_ATPase_I PF01496.14 KEZ42994.1 - 3.3 5.4 5.6 4.9 4.8 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 KEZ42994.1 - 4.5 6.8 8.2 2 7.9 3.7 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tmemb_cc2 PF10267.4 KEZ42994.1 - 6.3 5.2 13.0 0.97 7.9 6.1 1.7 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Abhydrolase_3 PF07859.8 KEZ42995.1 - 5.6e-42 143.6 0.0 1.2e-41 142.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KEZ42995.1 - 3.4e-05 22.6 0.0 0.00018 20.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KEZ42995.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family HMG_CoA_synt_C PF08540.5 KEZ42996.1 - 2.1e-99 332.5 0.1 2.7e-99 332.2 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KEZ42996.1 - 4e-93 309.7 0.1 6e-93 309.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BCS1_N PF08740.6 KEZ42997.1 - 1.6e-51 174.5 2.6 1.6e-51 174.5 1.8 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KEZ42997.1 - 8.9e-18 64.7 0.0 5.6e-16 58.9 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ42997.1 - 5.6e-05 23.2 0.0 0.00013 22.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KEZ42997.1 - 0.0001 21.7 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ42997.1 - 0.00012 22.8 0.0 0.00053 20.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEZ42997.1 - 0.00083 18.4 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KEZ42997.1 - 0.0016 18.1 0.0 0.006 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KEZ42997.1 - 0.009 14.9 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 KEZ42997.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_22 PF13401.1 KEZ42997.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KEZ42997.1 - 0.026 13.6 0.0 0.068 12.2 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KEZ42997.1 - 0.033 13.9 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain AAA_18 PF13238.1 KEZ42997.1 - 0.066 13.5 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEZ42997.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KEZ42997.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 1 0 RNA helicase DUF2798 PF11391.3 KEZ42998.1 - 0.073 12.8 0.6 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) DUF1501 PF07394.7 KEZ42998.1 - 0.11 11.2 0.6 0.19 10.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Yae1_N PF09811.4 KEZ42998.1 - 0.19 11.2 0.0 3 7.4 0.0 2.2 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Homoserine_dh PF00742.14 KEZ42999.1 - 4.1e-52 176.4 0.0 5.5e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KEZ42999.1 - 1.5e-18 67.3 0.0 2.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain RRM_1 PF00076.17 KEZ43000.1 - 4.1e-20 71.1 0.1 1.9e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ43000.1 - 1.1e-16 60.5 0.0 2.6e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ43000.1 - 1.7e-16 59.8 0.0 7.9e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEX11 PF05648.9 KEZ43001.1 - 1.9e-75 252.9 0.4 2.2e-75 252.7 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3411 PF11891.3 KEZ43001.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3411) FBPase PF00316.15 KEZ43002.1 - 2e-122 408.0 0.1 2.3e-122 407.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase bZIP_1 PF00170.16 KEZ43003.1 - 1.6e-05 24.7 6.5 1.6e-05 24.7 4.5 1.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ43003.1 - 0.00032 20.4 7.2 0.00062 19.5 5.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Striatin PF08232.7 KEZ43003.1 - 0.55 10.5 4.4 0.82 9.9 3.0 1.2 1 0 0 1 1 1 0 Striatin family Rcd1 PF04078.8 KEZ43004.1 - 2.5e-131 436.3 4.7 3e-131 436.0 3.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.20 KEZ43005.1 - 2e-65 220.5 0.0 2.9e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43005.1 - 9.6e-36 123.1 0.0 2.5e-35 121.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KEZ43005.1 - 2.2e-06 26.8 0.1 3e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEZ43005.1 - 2.7e-05 23.2 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEZ43005.1 - 0.00079 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KEZ43005.1 - 0.0011 18.7 0.0 0.0057 16.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ43005.1 - 0.0063 15.8 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 KEZ43005.1 - 0.012 15.2 0.5 0.06 12.9 0.3 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase EcKinase PF02958.15 KEZ43005.1 - 0.081 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase WaaY PF06176.6 KEZ43005.1 - 0.091 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1604 PF07713.8 KEZ43006.1 - 9.5e-35 118.2 0.4 1.7e-34 117.4 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KEZ43006.1 - 4.4e-06 26.3 1.8 0.00016 21.4 0.5 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KEZ43006.1 - 0.012 15.4 0.1 0.054 13.3 0.0 2.2 2 0 0 2 2 2 0 DExH-box splicing factor binding site WD40 PF00400.27 KEZ43007.1 - 5.5e-45 149.7 13.1 5.1e-12 45.1 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KEZ43007.1 - 2.7e-08 33.7 6.1 0.015 15.0 0.2 3.7 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term bZIP_1 PF00170.16 KEZ43008.1 - 1.6e-12 47.1 10.3 8.6e-11 41.6 5.4 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KEZ43008.1 - 3.5e-05 23.5 13.1 0.0001 22.0 7.9 2.2 2 0 0 2 2 2 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 KEZ43008.1 - 0.013 14.5 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein MARVEL PF01284.18 KEZ43009.1 - 7.6e-13 48.5 19.4 1e-12 48.0 13.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF1049 PF06305.6 KEZ43009.1 - 8.9 5.8 8.6 0.72 9.3 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2306 PF10067.4 KEZ43009.1 - 9.1 6.4 12.1 2.2 8.4 3.3 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) Alkyl_sulf_dimr PF14863.1 KEZ43010.1 - 1.7e-54 183.9 0.0 2.9e-54 183.1 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 KEZ43010.1 - 7.2e-24 84.5 0.1 1.8e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PX PF00787.19 KEZ43010.1 - 7.9e-24 83.6 0.0 1.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 PX domain Alkyl_sulf_C PF14864.1 KEZ43010.1 - 1.6e-17 63.6 0.0 3.7e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.2 KEZ43010.1 - 0.00013 21.5 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Mito_carr PF00153.22 KEZ43011.1 - 2.2e-72 238.8 4.9 8.7e-25 86.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 KEZ43012.1 - 0.01 15.7 11.3 0.018 14.9 7.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 KEZ43013.1 - 1.8e-17 62.6 0.1 2.4e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KEZ43013.1 - 0.0085 16.5 7.0 0.014 15.8 4.9 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF3628 PF12300.3 KEZ43013.1 - 9.7 6.1 11.7 15 5.5 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) UCH PF00443.24 KEZ43014.1 - 3.5e-52 177.1 0.0 4.4e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ43014.1 - 6.7e-21 74.9 0.5 3e-20 72.8 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KEZ43014.1 - 2.3e-10 39.7 0.2 5.4e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Striatin PF08232.7 KEZ43015.1 - 0.19 12.0 4.4 0.24 11.6 3.0 1.1 1 0 0 1 1 1 0 Striatin family GAT PF03127.9 KEZ43016.1 - 4.2e-17 61.9 0.6 1e-16 60.7 0.4 1.6 1 0 0 1 1 1 1 GAT domain Zn_clus PF00172.13 KEZ43017.1 - 1.8e-07 30.9 7.2 2.7e-07 30.3 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 KEZ43018.1 - 3.7e-17 62.5 0.1 5e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43018.1 - 9.7e-16 57.7 0.0 1.3e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ43018.1 - 2.6e-14 53.7 0.0 4.1e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43018.1 - 6.6e-14 52.1 0.0 1.4e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ43018.1 - 1.1e-12 48.2 0.0 2.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ43018.1 - 1.7e-09 37.9 0.0 3.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ43018.1 - 1.7e-08 33.9 0.0 2.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEZ43018.1 - 2.2e-08 34.1 0.1 4.5e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ43018.1 - 0.00018 20.9 0.0 0.00051 19.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KEZ43018.1 - 0.00038 20.1 0.0 0.00092 18.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KEZ43018.1 - 0.0053 16.2 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 KEZ43018.1 - 0.021 13.9 0.0 0.044 12.8 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase His_Phos_1 PF00300.17 KEZ43019.1 - 1.1e-31 110.0 0.0 1.3e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UBX PF00789.15 KEZ43020.1 - 5.9e-07 29.4 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 KEZ43020.1 - 4.1e-05 23.0 0.0 9.4e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain CAF-1_p150 PF11600.3 KEZ43020.1 - 0.48 9.7 12.2 0.86 8.9 8.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 KEZ43021.1 - 0.0017 17.5 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 KEZ43022.1 - 1.6e-21 76.9 0.1 2.6e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sec2p PF06428.6 KEZ43023.1 - 1.5e-23 82.5 19.1 1.5e-23 82.5 13.2 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Pox_A_type_inc PF04508.7 KEZ43023.1 - 0.23 11.3 7.5 3 7.8 0.6 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FUSC PF04632.7 KEZ43023.1 - 0.31 9.4 7.2 0.43 8.9 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.5 KEZ43023.1 - 3.2 7.8 13.4 21 5.2 0.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 KEZ43023.1 - 7.8 4.8 16.1 12 4.1 11.2 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_S46 PF10459.4 KEZ43023.1 - 8.3 4.6 16.8 12 4.2 11.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Ank_2 PF12796.2 KEZ43024.1 - 1e-81 269.3 26.6 7.1e-20 71.1 0.1 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43024.1 - 1.2e-52 173.1 7.5 7.3e-07 28.6 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.1 KEZ43024.1 - 6e-43 140.5 1.7 0.00019 21.3 0.0 9.5 9 1 0 9 9 9 8 Ankyrin repeat HET PF06985.6 KEZ43024.1 - 1.7e-39 135.1 0.2 4e-39 133.9 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.1 KEZ43024.1 - 5.2e-35 119.2 5.7 4.2e-09 36.6 0.0 6.5 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ43024.1 - 2.1e-33 113.5 15.4 3.9e-09 36.4 0.1 7.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) PMT PF02366.13 KEZ43025.1 - 8e-78 261.1 16.4 1.5e-77 260.3 11.4 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KEZ43025.1 - 3.9e-55 186.3 0.1 7.6e-55 185.3 0.1 1.5 1 0 0 1 1 1 1 MIR domain zf-C2H2 PF00096.21 KEZ43026.1 - 3e-08 33.5 8.2 4.3e-05 23.5 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ43026.1 - 7.4e-06 25.9 7.7 0.002 18.3 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KEZ43026.1 - 0.011 15.8 0.9 0.027 14.5 0.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 KEZ43026.1 - 0.059 13.6 9.7 1.1 9.6 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Med31 PF05669.7 KEZ43029.1 - 1e-37 127.9 0.1 1.1e-37 127.8 0.1 1.0 1 0 0 1 1 1 1 SOH1 HisG_C PF08029.6 KEZ43030.1 - 0.044 13.7 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 HisG, C-terminal domain CFEM PF05730.6 KEZ43031.1 - 3e-08 33.3 13.9 6e-08 32.3 9.7 1.5 1 0 0 1 1 1 1 CFEM domain PRP21_like_P PF12230.3 KEZ43032.1 - 1.5e-58 198.0 12.6 1.4e-57 194.9 8.7 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KEZ43032.1 - 5.2e-39 131.6 1.2 2.4e-20 71.9 0.1 2.4 2 0 0 2 2 2 2 Surp module SNARE PF05739.14 KEZ43033.1 - 1.5e-18 66.2 0.8 1.5e-18 66.2 0.6 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KEZ43033.1 - 2.2e-14 53.4 1.3 2.2e-14 53.4 0.9 2.7 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KEZ43033.1 - 0.0013 18.2 6.5 0.076 12.5 0.3 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 KEZ43033.1 - 0.02 14.3 0.0 0.048 13.0 0.0 1.7 1 0 0 1 1 1 0 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 KEZ43033.1 - 0.026 14.3 1.0 0.26 11.1 0.1 2.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus zf-C4H2 PF10146.4 KEZ43033.1 - 0.12 12.3 1.9 5.6 6.9 0.1 2.3 1 1 0 2 2 2 0 Zinc finger-containing protein SF-assemblin PF06705.6 KEZ43033.1 - 0.17 11.0 8.7 0.59 9.2 2.0 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin Atg14 PF10186.4 KEZ43033.1 - 0.36 9.7 11.3 0.42 9.4 0.8 3.0 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Prominin PF05478.6 KEZ43033.1 - 0.38 8.2 3.2 6.7 4.1 0.0 2.1 2 0 0 2 2 2 0 Prominin BLOC1_2 PF10046.4 KEZ43033.1 - 0.41 10.8 4.1 1 9.5 0.1 2.9 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 KEZ43033.1 - 1.8 8.8 7.2 63 3.9 0.2 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 KEZ43033.1 - 5.4 5.5 9.1 0.87 8.1 2.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Aldo_ket_red PF00248.16 KEZ43034.1 - 1.7e-53 181.3 0.0 2e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 KEZ43035.1 - 2.7e-24 85.0 0.0 6.2e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ43035.1 - 6.3e-16 58.1 0.5 1.1e-15 57.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KEZ43035.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 KEZ43035.1 - 0.1 11.6 0.1 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 KEZ43036.1 - 3e-29 102.1 2.8 3.9e-29 101.7 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43036.1 - 1.7e-28 100.0 0.3 2e-28 99.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43036.1 - 2.8e-10 40.1 2.4 1.1e-09 38.2 1.7 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ43036.1 - 5e-07 29.4 0.2 8.8e-07 28.5 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NACHT PF05729.7 KEZ43037.1 - 2.4e-08 33.7 0.0 6.7e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ43037.1 - 1.9e-06 27.9 0.0 6.1e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ43037.1 - 3.6e-05 23.9 0.0 0.00018 21.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KEZ43037.1 - 0.00076 19.0 0.0 0.0029 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KEZ43037.1 - 0.014 16.2 0.0 0.064 14.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEZ43037.1 - 0.015 15.6 0.2 0.015 15.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ43037.1 - 0.03 14.4 0.2 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 KEZ43037.1 - 0.035 14.3 0.2 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 KEZ43037.1 - 0.069 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KEZ43037.1 - 0.094 13.0 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 KEZ43037.1 - 0.11 12.4 1.2 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding adh_short PF00106.20 KEZ43038.1 - 9.3e-30 103.7 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43038.1 - 3.6e-22 79.3 0.0 4.3e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43038.1 - 2.2e-11 43.7 0.1 5.8e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ43038.1 - 0.00021 20.7 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEZ43038.1 - 0.008 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KEZ43038.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Abhydrolase_6 PF12697.2 KEZ43039.1 - 2e-12 47.5 0.4 5e-12 46.1 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ43039.1 - 1.2e-10 41.2 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 KEZ43039.1 - 1.4e-10 40.3 0.0 1.8e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 KEZ43039.1 - 8.8e-07 28.3 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KEZ43039.1 - 8.5e-06 25.3 0.1 1.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 KEZ43039.1 - 0.0034 16.8 0.0 0.019 14.3 0.0 2.0 1 1 0 1 1 1 1 Putative esterase DLH PF01738.13 KEZ43039.1 - 0.013 14.8 0.0 0.07 12.4 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.4 KEZ43039.1 - 0.035 13.3 0.1 0.077 12.2 0.1 1.5 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 KEZ43039.1 - 0.064 12.8 0.0 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 KEZ43040.1 - 4.1e-10 39.5 0.1 6.2e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ43040.1 - 4.8e-10 39.4 0.1 6.7e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEZ43040.1 - 0.0032 17.6 0.0 0.0039 17.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEZ43040.1 - 0.0048 16.7 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.7 KEZ43040.1 - 0.014 13.8 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Acetyltransf_4 PF13420.1 KEZ43040.1 - 0.029 14.3 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEZ43040.1 - 0.059 13.4 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lyase_1 PF00206.15 KEZ43041.1 - 6.5e-110 367.1 0.0 8.7e-110 366.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KEZ43041.1 - 8.2e-23 80.2 0.0 1.8e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus AKNA PF12443.3 KEZ43041.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor TFIIS_C PF01096.13 KEZ43042.1 - 4.6e-20 70.9 2.4 4.6e-20 70.9 1.6 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KEZ43042.1 - 1.1e-06 28.1 0.1 8.1e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit C1_3 PF07649.7 KEZ43042.1 - 0.6 10.2 0.2 0.6 10.2 0.1 2.3 2 1 0 2 2 2 0 C1-like domain Zn_Tnp_IS1 PF03811.8 KEZ43042.1 - 2 8.0 8.0 0.97 8.9 0.2 2.8 3 0 0 3 3 3 0 InsA N-terminal domain DUF1687 PF07955.6 KEZ43043.1 - 7.6e-20 71.2 0.1 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 KEZ43043.1 - 0.02 14.9 0.0 1.1 9.3 0.0 2.3 1 1 0 1 1 1 0 ArsC family TOMM6 PF15184.1 KEZ43043.1 - 0.024 13.9 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog CGI-121 PF08617.5 KEZ43043.1 - 0.052 13.2 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Kinase binding protein CGI-121 Ribosomal_L14e PF01929.12 KEZ43044.1 - 2.5e-23 82.2 2.3 3.5e-23 81.7 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KEZ43044.1 - 0.002 17.7 0.0 0.0049 16.5 0.0 1.7 1 0 0 1 1 1 1 KOW motif BAH PF01426.13 KEZ43044.1 - 0.11 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 BAH domain NAC PF01849.13 KEZ43045.1 - 8.4e-26 89.2 0.2 1.3e-24 85.5 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KEZ43045.1 - 0.00011 21.9 0.3 0.00022 20.9 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain CENP-B_dimeris PF09026.5 KEZ43045.1 - 0.06 13.5 7.8 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SpoIIIAH PF12685.2 KEZ43045.1 - 0.7 9.3 11.7 0.23 10.9 4.8 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein EBV-NA3 PF05009.7 KEZ43045.1 - 1.2 8.2 13.6 0.22 10.7 3.3 2.4 2 1 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 KEZ43045.1 - 3.1 5.7 10.7 0.071 11.1 2.7 1.6 2 0 0 2 2 2 0 CDC45-like protein PQ-loop PF04193.9 KEZ43046.1 - 3.8e-37 125.6 14.5 1.5e-21 75.6 0.4 3.0 3 0 0 3 3 3 2 PQ loop repeat S1-P1_nuclease PF02265.11 KEZ43047.1 - 2.2e-67 227.3 0.1 2.5e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PSI_PSAK PF01241.13 KEZ43047.1 - 0.025 14.5 0.3 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK Semialdhyde_dhC PF02774.13 KEZ43050.1 - 8.9e-37 126.7 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KEZ43050.1 - 1.8e-29 102.5 0.0 3.3e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KEZ43050.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GPI2 PF06432.6 KEZ43052.1 - 2e-110 368.5 0.4 3.4e-110 367.8 0.2 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Gly-zipper_Omp PF13488.1 KEZ43052.1 - 3.4 7.3 13.1 0.95 9.1 3.2 2.3 2 0 0 2 2 2 0 Glycine zipper Macoilin PF09726.4 KEZ43052.1 - 6.7 4.8 8.2 9.3 4.3 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Ras PF00071.17 KEZ43053.1 - 9.8e-43 145.3 0.0 1.3e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ43053.1 - 1.8e-12 47.8 0.0 3.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KEZ43053.1 - 7e-06 25.5 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KEZ43053.1 - 1.1e-05 24.7 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Scytalone_dh PF02982.9 KEZ43053.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase zf-MYND PF01753.13 KEZ43054.1 - 0.044 13.6 20.7 0.027 14.3 2.9 3.5 3 1 0 3 3 3 0 MYND finger Plasmod_MYXSPDY PF07981.6 KEZ43054.1 - 0.16 11.7 0.2 0.36 10.5 0.1 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY DUF2203 PF09969.4 KEZ43054.1 - 0.19 11.9 4.1 21 5.3 0.0 3.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) zf-HIT PF04438.11 KEZ43054.1 - 0.39 10.4 10.4 0.68 9.6 0.8 3.0 2 1 0 2 2 2 0 HIT zinc finger ECM11 PF15463.1 KEZ43054.1 - 0.85 9.8 10.1 0.083 13.1 0.4 3.1 2 2 1 3 3 3 0 Extracellular mutant protein 11 Ecl1 PF12855.2 KEZ43054.1 - 1.5 8.1 10.7 3.7 6.8 1.9 2.6 2 0 0 2 2 2 0 Life-span regulatory factor Mnd1 PF03962.10 KEZ43054.1 - 3.6 7.2 9.1 12 5.4 2.7 2.6 2 1 1 3 3 3 0 Mnd1 family SF3b10 PF07189.6 KEZ43055.1 - 4.5e-39 132.1 0.0 5.5e-39 131.8 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.14 KEZ43056.1 - 7.4e-21 74.3 0.0 9.5e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 MAGE family SLS PF14611.1 KEZ43057.1 - 8.9e-27 93.8 1.3 8.9e-27 93.8 0.9 2.0 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.22 KEZ43058.1 - 2.2e-49 167.4 0.0 3.5e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEZ43058.1 - 2e-37 127.3 0.1 5.2e-37 125.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEZ43058.1 - 1.1e-18 67.1 1.1 3.8e-18 65.3 0.8 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KEZ43058.1 - 0.00014 21.4 0.2 0.00036 20.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KEZ43058.1 - 0.00037 20.4 0.1 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEZ43058.1 - 0.034 13.2 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family PDZ PF00595.19 KEZ43058.1 - 0.044 13.9 0.7 0.22 11.7 0.1 2.5 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Miro PF08477.8 KEZ43058.1 - 0.097 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 KEZ43058.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Septin Adaptin_N PF01602.15 KEZ43059.1 - 1.2e-113 380.2 1.5 1.5e-113 379.9 1.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KEZ43059.1 - 1.1e-58 197.3 2.1 2.2e-58 196.3 1.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KEZ43059.1 - 7.7e-15 54.9 1.7 4.9e-05 23.5 0.1 6.0 3 1 3 6 6 6 3 HEAT repeats Alpha_adaptin_C PF02296.11 KEZ43059.1 - 0.00038 20.3 0.1 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.11 KEZ43059.1 - 0.0033 17.7 0.4 9.2 7.0 0.0 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 KEZ43059.1 - 0.022 14.1 4.4 0.044 13.1 0.1 3.1 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.1 KEZ43059.1 - 0.18 12.3 3.6 0.61 10.6 0.5 3.5 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.17 KEZ43059.1 - 0.19 11.9 9.7 1.9 8.7 0.3 5.2 6 0 0 6 6 6 0 HEAT repeat CDP-OH_P_transf PF01066.16 KEZ43060.1 - 1.7e-17 63.5 1.2 1.7e-17 63.5 0.9 2.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HATPase_c PF02518.21 KEZ43061.1 - 1.2e-24 86.1 0.2 2.1e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KEZ43061.1 - 5.3e-21 74.3 0.1 1.6e-20 72.8 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KEZ43061.1 - 6.3e-21 74.4 0.1 2.7e-19 69.2 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.6 KEZ43061.1 - 6.7e-18 64.5 4.3 1.3e-09 38.0 0.5 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 KEZ43061.1 - 3.5e-13 49.8 0.0 2.1e-06 28.0 0.0 3.5 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 KEZ43061.1 - 5.2e-09 35.8 0.0 2.1e-05 24.2 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KEZ43061.1 - 6.2e-08 32.6 0.2 5.6e-06 26.3 0.1 2.9 3 0 0 3 3 3 1 PAS fold Cytochrom_B561 PF03188.11 KEZ43062.1 - 6.8e-17 61.5 8.4 1.2e-16 60.7 5.8 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4006 PF13179.1 KEZ43062.1 - 0.0027 17.1 1.7 2.7 7.6 0.0 3.1 3 0 0 3 3 3 2 Family of unknown function (DUF4006) PepSY_TM_1 PF13172.1 KEZ43062.1 - 0.003 17.2 0.6 0.003 17.2 0.4 3.7 4 0 0 4 4 4 2 PepSY-associated TM helix DUF4079 PF13301.1 KEZ43062.1 - 0.89 9.5 16.3 0.91 9.5 8.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Ferric_reduct PF01794.14 KEZ43062.1 - 1.5 8.8 15.1 0.25 11.4 6.5 2.3 2 1 0 2 2 2 0 Ferric reductase like transmembrane component DUF2868 PF11067.3 KEZ43062.1 - 7.9 5.5 10.3 0.61 9.1 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Allantoicase PF03561.10 KEZ43063.1 - 4.9e-108 357.2 0.3 4.6e-58 195.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.14 KEZ43064.1 - 5.2e-19 68.0 0.9 9e-12 44.8 0.1 2.5 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 KEZ43064.1 - 1.8e-18 66.6 0.1 4.4e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43064.1 - 6.9e-16 57.1 0.1 2.8e-06 26.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KEZ43064.1 - 2.1e-12 47.2 0.7 7.8e-07 29.4 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ43064.1 - 2.2e-11 43.5 0.1 1.8e-07 31.1 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43064.1 - 8.9e-10 37.8 0.1 0.011 15.9 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat APC_CDC26 PF10471.4 KEZ43064.1 - 3.7 8.3 10.1 18 6.1 5.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 RabGAP-TBC PF00566.13 KEZ43065.1 - 6.2e-32 110.7 0.0 9.8e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HATPase_c PF02518.21 KEZ43066.1 - 2.3e-28 98.1 0.0 5.6e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEZ43066.1 - 2.2e-20 72.7 0.1 6.5e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KEZ43066.1 - 2.2e-20 72.4 0.5 8.1e-20 70.5 0.3 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KEZ43066.1 - 7.2e-14 52.1 0.1 1e-12 48.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 KEZ43066.1 - 1.7e-13 51.3 0.1 7.8e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 KEZ43066.1 - 7.6e-09 35.7 0.0 2.2e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KEZ43066.1 - 2.5e-06 26.8 0.0 4.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.7 KEZ43066.1 - 0.00045 19.9 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain HATPase_c_3 PF13589.1 KEZ43066.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ArgK PF03308.11 KEZ43066.1 - 0.016 14.0 0.1 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein HisKA_3 PF07730.8 KEZ43066.1 - 0.025 14.8 3.6 0.13 12.6 0.1 3.0 2 0 0 2 2 2 0 Histidine kinase Pkinase_Tyr PF07714.12 KEZ43066.1 - 0.037 13.0 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase NB-ARC PF00931.17 KEZ43066.1 - 0.26 10.1 0.0 2.4 6.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NAD_binding_8 PF13450.1 KEZ43067.1 - 4.9e-10 39.2 0.0 1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEZ43067.1 - 5.3e-07 29.0 0.0 4.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KEZ43067.1 - 2.8e-05 24.2 0.1 8.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ43067.1 - 0.0081 16.0 0.0 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ43067.1 - 0.0081 15.2 0.1 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ43067.1 - 0.024 13.1 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 KEZ43067.1 - 0.03 14.1 0.1 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KEZ43067.1 - 0.037 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KEZ43067.1 - 0.05 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KEZ43067.1 - 0.059 12.4 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 KEZ43067.1 - 0.067 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ43067.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KEZ43067.1 - 0.13 11.1 0.5 0.31 9.9 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein TPT PF03151.11 KEZ43068.1 - 1.9e-26 92.5 14.0 1.9e-26 92.5 9.7 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KEZ43068.1 - 0.0021 18.1 31.3 0.035 14.1 7.9 2.8 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 KEZ43068.1 - 0.04 12.8 18.7 0.13 11.1 13.0 1.8 1 1 0 1 1 1 0 UAA transporter family Ribosomal_L27e PF01777.13 KEZ43069.1 - 5.2e-38 129.0 2.5 6.9e-38 128.6 1.7 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KEZ43069.1 - 0.0062 16.2 0.8 0.0062 16.2 0.6 2.2 3 0 0 3 3 3 1 KOW motif Ssl1 PF04056.9 KEZ43070.1 - 2.8e-73 245.6 0.0 3.7e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KEZ43070.1 - 3.9e-19 68.4 8.2 3.9e-19 68.4 5.7 2.8 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 KEZ43070.1 - 1.1e-10 41.8 0.0 2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Chs3p PF12271.3 KEZ43071.1 - 3e-102 341.5 4.5 3.5e-102 341.3 3.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF973 PF06157.6 KEZ43071.1 - 1.8 7.4 17.2 0.22 10.4 4.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF973) DUF202 PF02656.10 KEZ43071.1 - 2.3 8.5 0.0 2.3 8.5 0.0 4.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Sugar_tr PF00083.19 KEZ43072.1 - 1.2e-93 314.1 15.9 1.4e-93 313.9 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43072.1 - 4.8e-21 74.8 48.6 5.8e-20 71.3 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ43072.1 - 7.6e-05 21.2 5.4 7.6e-05 21.2 3.8 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein Complex1_LYR PF05347.10 KEZ43072.1 - 0.00011 21.9 0.9 0.00011 21.9 0.6 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Mito_carr PF00153.22 KEZ43073.1 - 2.6e-44 148.8 7.7 8e-17 60.7 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2293 PF10056.4 KEZ43074.1 - 1.3e-27 95.5 0.6 4e-27 93.9 0.4 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) DUF4475 PF14753.1 KEZ43074.1 - 0.22 11.0 0.0 0.45 9.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4475) CUE PF02845.11 KEZ43075.1 - 2.1e-12 46.2 0.0 3.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Ank_2 PF12796.2 KEZ43076.1 - 1.4e-36 124.7 1.4 5.5e-13 49.0 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ43076.1 - 3.5e-26 91.0 1.9 4.9e-10 39.6 0.0 4.8 4 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KEZ43076.1 - 4e-25 86.3 8.3 2.9e-06 26.7 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KEZ43076.1 - 1.9e-19 69.2 6.6 4.5e-06 26.7 0.2 5.7 2 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43076.1 - 4.7e-16 57.2 8.0 0.00011 22.0 0.0 7.1 9 0 0 9 9 9 4 Ankyrin repeat SPX PF03105.14 KEZ43076.1 - 5.6e-15 55.8 7.8 4.7e-12 46.2 0.5 2.2 1 1 1 2 2 2 2 SPX domain GDPD PF03009.12 KEZ43076.1 - 0.00012 21.6 0.0 0.00033 20.2 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Coa1 PF08695.5 KEZ43078.1 - 1.3e-40 137.5 0.0 1.8e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2505 PF10698.4 KEZ43078.1 - 0.057 12.9 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) PITH PF06201.8 KEZ43079.1 - 7.1e-45 152.4 0.1 8.3e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain NACHT PF05729.7 KEZ43080.1 - 6e-09 35.7 0.0 1.5e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ43080.1 - 0.0002 21.4 0.0 0.0023 18.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ43080.1 - 0.015 15.2 1.3 0.3 11.0 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain RFC1 PF08519.7 KEZ43080.1 - 0.024 14.3 0.3 0.071 12.8 0.2 1.8 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain UBN2_2 PF14227.1 KEZ43080.1 - 0.034 13.6 0.3 0.22 11.0 0.1 2.4 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Rrn6 PF10214.4 KEZ43081.1 - 2.6e-49 168.0 20.3 1.3e-44 152.4 0.6 2.9 2 1 1 3 3 3 2 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 KEZ43082.1 - 9.7e-22 76.7 0.1 3.1e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 APG6 PF04111.7 KEZ43082.1 - 0.21 10.6 7.4 0.34 9.9 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1014 PF06244.7 KEZ43082.1 - 0.44 10.7 9.2 0.69 10.1 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Atg14 PF10186.4 KEZ43082.1 - 1 8.2 9.1 1.8 7.4 6.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 KEZ43082.1 - 2.2 8.7 11.8 0.3 11.5 3.6 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 KEZ43082.1 - 2.7 7.5 14.2 1.3 8.6 2.5 2.4 2 1 1 3 3 3 0 Mnd1 family AAA_23 PF13476.1 KEZ43082.1 - 3.2 8.0 6.9 3.3 7.9 4.0 1.5 2 0 0 2 2 2 0 AAA domain DegS PF05384.6 KEZ43082.1 - 8.5 5.5 17.0 0.12 11.5 2.2 2.6 2 1 1 3 3 3 0 Sensor protein DegS zinc_ribbon_6 PF14599.1 KEZ43083.1 - 8.2e-26 89.5 2.5 8.2e-26 89.5 1.8 4.1 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 KEZ43083.1 - 3.8e-15 55.7 22.7 3.8e-15 55.7 15.7 4.4 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 KEZ43083.1 - 1.7e-08 34.1 5.9 1.7e-08 34.1 4.1 4.9 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEZ43083.1 - 5.2e-08 32.7 5.7 5.2e-08 32.7 4.0 5.5 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ43083.1 - 1.1e-07 31.3 7.1 1.1e-07 31.3 4.9 6.0 2 1 2 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ43083.1 - 1.6e-06 27.6 5.0 1.6e-06 27.6 3.5 5.6 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ43083.1 - 6.9e-05 22.4 11.5 6.9e-05 22.4 7.9 6.3 3 2 1 4 4 4 1 zinc-RING finger domain Rtf2 PF04641.7 KEZ43083.1 - 0.017 14.3 4.8 0.04 13.1 3.3 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger PMT PF02366.13 KEZ43084.1 - 6.7e-82 274.5 15.8 6.7e-82 274.5 10.9 2.9 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KEZ43084.1 - 4.4e-39 133.9 0.2 5.9e-39 133.5 0.1 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.3 KEZ43084.1 - 0.078 12.5 3.9 0.12 11.9 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Choline_transpo PF04515.7 KEZ43085.1 - 2.7e-16 59.2 32.8 6.1e-14 51.5 13.3 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter WW PF00397.21 KEZ43086.1 - 5.2e-08 32.6 6.2 9.4e-08 31.7 4.3 1.5 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.5 KEZ43087.1 - 1.3e-29 102.5 0.0 1.7e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 KEZ43087.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain FAD_binding_4 PF01565.18 KEZ43088.1 - 1e-07 31.5 0.1 1.2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF1097 PF06496.6 KEZ43088.1 - 0.083 12.6 1.8 0.13 12.1 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1097) PsbN PF02468.10 KEZ43088.1 - 0.14 11.7 0.3 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) CPSase_L_D2 PF02786.12 KEZ43089.1 - 4.8e-64 215.5 0.0 8.5e-64 214.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KEZ43089.1 - 1.3e-36 125.0 0.0 3.2e-36 123.7 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEZ43089.1 - 6.5e-19 67.9 0.0 1.6e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KEZ43089.1 - 9.6e-15 54.7 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEZ43089.1 - 9.3e-12 44.3 0.0 2.4e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KEZ43089.1 - 3.6e-08 33.0 0.0 1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEZ43089.1 - 2.3e-07 30.3 0.0 1e-06 28.2 0.0 2.1 1 1 1 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KEZ43089.1 - 3.8e-07 30.0 0.0 6.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEZ43089.1 - 0.0006 19.3 0.0 0.027 13.9 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.1 KEZ43089.1 - 0.019 13.7 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp Biotin_lipoyl PF00364.17 KEZ43089.1 - 0.034 13.7 0.1 0.29 10.8 0.1 2.5 1 1 0 1 1 1 0 Biotin-requiring enzyme YqfD PF06898.6 KEZ43089.1 - 0.063 11.9 0.0 0.095 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Cro PF09048.5 KEZ43089.1 - 0.08 12.5 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Cro Biotin_lipoyl_2 PF13533.1 KEZ43089.1 - 0.084 12.5 0.0 0.85 9.3 0.0 2.6 1 1 0 1 1 1 0 Biotin-lipoyl like NYD-SP12_N PF15015.1 KEZ43089.1 - 0.14 10.4 0.1 0.27 9.4 0.0 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated, N-terminal Fungal_trans PF04082.13 KEZ43090.1 - 9.5e-07 27.9 0.0 1.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3500 PF12006.3 KEZ43091.1 - 2.3e-49 168.0 0.1 3.1e-39 134.7 0.0 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3500) MFS_1 PF07690.11 KEZ43093.1 - 3.1e-22 78.7 21.0 1.3e-13 50.3 6.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily HMGL-like PF00682.14 KEZ43094.1 - 5.5e-43 147.3 0.0 9.4e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ECH PF00378.15 KEZ43094.1 - 6.5e-40 136.7 0.0 1.1e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Carboxyl_trans PF01039.17 KEZ43095.1 - 1.1e-88 297.8 0.0 1e-52 179.1 0.0 2.9 2 1 0 2 2 2 2 Carboxyl transferase domain MFS_1 PF07690.11 KEZ43096.1 - 2.9e-20 72.2 28.2 3.6e-20 71.9 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ43097.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain IBR PF01485.16 KEZ43099.1 - 0.23 11.3 1.0 0.88 9.4 0.7 1.9 1 1 0 1 1 1 0 IBR domain TauD PF02668.11 KEZ43100.1 - 4.2e-27 95.4 0.0 5.7e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fasciclin PF02469.17 KEZ43101.1 - 1.9e-43 147.5 0.2 2.3e-20 72.8 0.2 2.2 2 0 0 2 2 2 2 Fasciclin domain PBP PF01161.15 KEZ43102.1 - 1.8e-07 31.0 0.0 2.2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Aldedh PF00171.17 KEZ43103.1 - 9.2e-45 152.8 0.0 2e-24 85.7 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF3328 PF11807.3 KEZ43103.1 - 2.8e-26 92.5 0.1 8.3e-25 87.7 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 KEZ43105.1 - 5.5e-15 54.9 37.7 4.1e-11 42.1 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43105.1 - 4.6e-14 51.8 24.0 3e-13 49.1 16.6 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DAO PF01266.19 KEZ43106.1 - 2.4e-54 184.5 0.0 2.8e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ43106.1 - 6.8e-07 29.3 0.0 0.00052 19.9 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ43106.1 - 3.9e-06 25.9 0.0 0.034 12.9 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KEZ43106.1 - 3.6e-05 22.8 0.0 0.003 16.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KEZ43106.1 - 7.8e-05 22.6 0.0 0.00021 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEZ43106.1 - 0.00011 20.7 0.0 0.057 11.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 KEZ43106.1 - 0.0002 21.5 0.0 0.052 13.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ43106.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KEZ43106.1 - 0.0025 17.5 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KEZ43106.1 - 0.0031 17.8 0.0 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KEZ43106.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KEZ43106.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 KEZ43106.1 - 0.098 11.5 0.0 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.20 KEZ43108.1 - 1.9e-30 105.9 0.4 3.5e-30 105.1 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43108.1 - 7.8e-22 78.2 0.1 4.8e-21 75.6 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43108.1 - 1.6e-14 54.0 0.1 2.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ43108.1 - 2.1e-05 24.1 0.0 7.6e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KEZ43108.1 - 0.023 15.1 0.4 0.046 14.1 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KEZ43108.1 - 0.036 12.9 0.0 0.051 12.4 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DFP PF04127.10 KEZ43108.1 - 0.037 13.6 1.0 2.2 7.8 0.3 2.3 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.5 KEZ43108.1 - 0.05 12.7 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_tranf_2_3 PF13641.1 KEZ43108.1 - 0.066 13.0 0.1 0.59 9.8 0.1 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 3HCDH_N PF02737.13 KEZ43108.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupredoxin_1 PF13473.1 KEZ43109.1 - 0.076 12.9 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Glucosamine_iso PF01182.15 KEZ43110.1 - 0.013 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_S8 PF00082.17 KEZ43111.1 - 0.00076 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.11 KEZ43112.1 - 1.9e-39 135.3 16.2 1.1e-38 132.9 11.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ43112.1 - 0.00013 20.5 4.7 0.00013 20.5 3.3 2.0 3 1 0 3 3 3 1 MFS/sugar transport protein Folate_carrier PF01770.13 KEZ43112.1 - 0.25 9.8 6.0 1.6 7.1 4.1 2.0 1 1 0 1 1 1 0 Reduced folate carrier Glyco_hydro_10 PF00331.15 KEZ43113.1 - 2.9e-90 302.5 0.2 3.2e-90 302.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 ABC_membrane PF00664.18 KEZ43114.1 - 9.8e-39 133.4 11.1 1.3e-38 133.0 7.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ43114.1 - 1e-34 119.8 0.0 1.9e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEZ43114.1 - 2.4e-08 34.2 0.0 0.00048 20.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 KEZ43114.1 - 3.5e-05 23.1 0.1 0.03 13.5 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEZ43114.1 - 9.6e-05 23.1 0.0 0.00021 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEZ43114.1 - 0.00059 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ43114.1 - 0.00091 19.3 0.0 0.0065 16.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEZ43114.1 - 0.0012 18.7 0.0 0.0071 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ43114.1 - 0.0012 18.9 0.2 0.0063 16.5 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 KEZ43114.1 - 0.0014 18.1 0.0 0.0077 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 KEZ43114.1 - 0.0028 17.1 0.1 0.008 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KEZ43114.1 - 0.0054 16.1 0.0 0.028 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEZ43114.1 - 0.012 15.9 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEZ43114.1 - 0.019 15.1 0.0 0.2 11.8 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1016 PF06250.6 KEZ43114.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) AAA_28 PF13521.1 KEZ43114.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KEZ43114.1 - 0.03 14.2 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.4 KEZ43114.1 - 0.031 12.8 0.1 1.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.1 KEZ43114.1 - 0.031 14.1 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KEZ43114.1 - 0.053 13.4 0.9 0.5 10.3 0.2 2.6 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KEZ43114.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 KEZ43114.1 - 0.059 12.9 0.1 0.41 10.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KEZ43114.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 KEZ43114.1 - 0.088 11.4 0.1 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NACHT PF05729.7 KEZ43114.1 - 0.097 12.3 0.1 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 KEZ43114.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3210 PF11489.3 KEZ43114.1 - 0.35 9.5 4.9 0.5 8.9 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) MFS_1 PF07690.11 KEZ43115.1 - 9.3e-31 106.8 28.3 1.2e-30 106.4 19.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.2 KEZ43116.1 - 6e-07 29.7 0.0 0.0013 19.0 0.0 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ43116.1 - 9.4e-06 26.0 0.4 3.5 8.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 KEZ43116.1 - 1.4e-05 24.6 0.2 1.2 9.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat p450 PF00067.17 KEZ43118.1 - 2.1e-69 234.2 0.0 2.5e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3136 PF11334.3 KEZ43118.1 - 0.003 16.9 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3136) Amino_oxidase PF01593.19 KEZ43119.1 - 1e-49 169.8 0.0 8.8e-35 120.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEZ43119.1 - 1.5e-12 47.3 1.2 4.5e-12 45.8 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ43119.1 - 1.7e-10 40.3 0.0 3.3e-08 32.8 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ43119.1 - 3.9e-09 35.8 0.2 1e-07 31.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KEZ43119.1 - 1.1e-07 31.3 0.0 3e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ43119.1 - 4.5e-07 29.2 0.0 8.3e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KEZ43119.1 - 2.1e-06 27.0 0.3 0.00011 21.3 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KEZ43119.1 - 2.9e-06 27.4 0.0 0.0052 16.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ43119.1 - 3.4e-06 25.8 0.1 1e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KEZ43119.1 - 1.2e-05 24.3 0.2 4.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KEZ43119.1 - 2.7e-05 24.1 0.2 5.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ43119.1 - 0.00025 21.4 0.1 0.00072 19.9 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ43119.1 - 0.004 16.1 0.3 0.0076 15.2 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein GDI PF00996.13 KEZ43119.1 - 0.059 11.6 0.0 0.12 10.6 0.0 1.5 2 0 0 2 2 2 0 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.9 KEZ43119.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans_2 PF11951.3 KEZ43120.1 - 3.1e-23 82.0 0.1 3.7e-23 81.7 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AKNA PF12443.3 KEZ43120.1 - 0.059 13.4 0.1 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor NmrA PF05368.8 KEZ43121.1 - 2.4e-17 63.0 0.0 1e-15 57.6 0.0 2.0 1 1 1 2 2 2 2 NmrA-like family KR PF08659.5 KEZ43121.1 - 6.5e-06 25.9 0.0 4.1e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEZ43121.1 - 0.00016 21.6 0.1 0.0017 18.3 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 KEZ43121.1 - 0.0033 17.3 0.1 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 KEZ43121.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF303 PF03629.13 KEZ43121.1 - 0.026 13.7 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF303) HgmA PF04209.8 KEZ43122.1 - 6.2e-163 542.1 0.0 7.1e-163 541.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.1 KEZ43123.1 - 1.1e-47 162.5 58.8 1.4e-47 162.1 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ43123.1 - 3.9e-19 68.3 47.1 5.6e-19 67.8 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 KEZ43123.1 - 3.8 7.4 5.4 3.8 7.4 0.2 3.1 2 0 0 2 2 2 0 Gram positive anchor FAD_binding_3 PF01494.14 KEZ43124.1 - 5.1e-16 58.6 5.3 3.3e-14 52.7 3.7 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ43124.1 - 1.3e-10 40.6 1.8 6.9e-05 21.9 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ43124.1 - 2.2e-07 30.1 0.1 5e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ43124.1 - 3.3e-06 27.1 0.7 2.6e-05 24.1 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ43124.1 - 4e-05 23.5 0.1 0.00013 21.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ43124.1 - 4.1e-05 23.9 0.3 0.0045 17.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ43124.1 - 0.0003 20.0 0.2 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 KEZ43124.1 - 0.00058 19.0 0.1 0.00079 18.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ43124.1 - 0.0007 18.1 0.2 0.012 14.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KEZ43124.1 - 0.0067 16.5 0.8 0.044 13.8 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ43124.1 - 0.0096 14.8 0.2 0.12 11.1 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KEZ43124.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 KEZ43124.1 - 0.063 12.8 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KEZ43124.1 - 0.09 11.3 0.1 8.1 4.9 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase EutQ PF06249.7 KEZ43125.1 - 1.4e-05 24.7 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 KEZ43125.1 - 0.00029 20.1 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 KEZ43125.1 - 0.0027 17.1 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KEZ43125.1 - 0.04 13.5 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Pirin PF02678.11 KEZ43125.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Pirin Aldedh PF00171.17 KEZ43126.1 - 3.7e-167 556.3 0.1 4.1e-167 556.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ43126.1 - 0.00081 18.2 0.0 0.0096 14.6 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Arch_ATPase PF01637.13 KEZ43128.1 - 8.3e-06 25.6 0.1 1.4e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KEZ43128.1 - 1.8e-05 24.7 3.1 0.0015 18.5 1.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 KEZ43128.1 - 0.0074 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Miro PF08477.8 KEZ43128.1 - 0.033 14.6 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KEZ43128.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KEZ43128.1 - 0.084 13.0 0.4 0.3 11.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain Hamartin PF04388.7 KEZ43129.1 - 0.13 10.9 3.8 0.13 10.9 2.6 1.1 1 0 0 1 1 1 0 Hamartin protein CAF-1_p150 PF11600.3 KEZ43129.1 - 1.7 7.9 20.1 0.023 14.0 8.8 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 KEZ43129.1 - 9.5 6.0 11.5 15 5.3 8.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GPI-anchored PF10342.4 KEZ43130.1 - 8.4e-06 26.1 0.1 1.9e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KEZ43130.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DNA_pol_A_exo1 PF01612.15 KEZ43131.1 - 9.5e-44 148.9 0.5 1.4e-43 148.4 0.4 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KEZ43131.1 - 9.3e-21 73.9 0.0 2.6e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KEZ43131.1 - 4.2e-10 39.2 0.0 1.1e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 HRDC domain TMEM51 PF15345.1 KEZ43131.1 - 0.98 9.0 16.8 2.7 7.6 11.6 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 SRP-alpha_N PF04086.8 KEZ43131.1 - 6.4 6.0 25.4 13 5.1 17.6 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Gpi1 PF05024.10 KEZ43132.1 - 7.6e-64 214.8 9.1 7.6e-64 214.8 6.3 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) TBCC PF07986.7 KEZ43132.1 - 1.4e-08 34.1 0.1 5.9e-08 32.1 0.0 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor C 7tm_1 PF00001.16 KEZ43132.1 - 0.00015 21.0 0.4 0.00034 19.8 0.2 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Cob_adeno_trans PF01923.13 KEZ43132.1 - 0.12 12.1 0.1 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase U1snRNP70_N PF12220.3 KEZ43132.1 - 1.3 9.4 6.8 0.36 11.1 0.4 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal iPGM_N PF06415.8 KEZ43133.1 - 2.7e-72 242.7 0.0 3.6e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 KEZ43133.1 - 8.7e-67 225.1 0.0 1.1e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 KEZ43133.1 - 7e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEZ43133.1 - 7.5e-07 28.6 0.0 2.4e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 KEZ43133.1 - 0.0058 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FRQ PF09421.5 KEZ43134.1 - 1.2e-266 887.3 59.0 3.6e-164 548.1 25.9 3.0 1 1 1 2 2 2 2 Frequency clock protein Prefoldin PF02996.12 KEZ43135.1 - 1.9e-35 121.0 0.4 1.9e-35 121.0 0.3 1.6 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 KEZ43135.1 - 0.0029 17.3 4.1 0.0041 16.8 0.0 2.5 2 1 0 3 3 3 1 Prefoldin subunit Syntaxin-6_N PF09177.6 KEZ43135.1 - 0.017 15.5 0.5 5.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal HR1 PF02185.11 KEZ43135.1 - 0.037 13.7 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 Hr1 repeat CRAL_TRIO PF00650.15 KEZ43136.1 - 5.8e-37 126.6 0.0 1e-36 125.8 0.0 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEZ43136.1 - 1.3e-08 34.8 0.8 7.2e-08 32.4 0.2 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEZ43136.1 - 0.005 16.7 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 KEZ43137.1 - 4.4e-06 26.7 0.1 1.3e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like SHMT PF00464.14 KEZ43138.1 - 4.3e-210 697.0 0.0 5.1e-210 696.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KEZ43138.1 - 0.00054 19.0 0.0 0.0011 17.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEZ43138.1 - 0.0011 17.8 0.0 0.0019 17.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KEZ43138.1 - 0.034 13.2 0.0 0.056 12.5 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase AAA PF00004.24 KEZ43140.1 - 1.1e-45 155.0 0.3 5e-45 152.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ43140.1 - 8.2e-09 35.3 0.4 2.9e-08 33.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEZ43140.1 - 3.8e-08 33.4 0.0 8.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEZ43140.1 - 4.9e-07 29.9 0.0 1.5e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KEZ43140.1 - 9.4e-07 27.9 0.2 2.1e-06 26.8 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KEZ43140.1 - 2.4e-06 27.7 2.6 0.001 19.1 0.0 2.8 2 1 1 3 3 2 2 AAA domain AAA_14 PF13173.1 KEZ43140.1 - 0.00013 21.8 0.1 0.00073 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ43140.1 - 0.00025 21.8 0.0 0.0023 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEZ43140.1 - 0.00036 19.6 0.0 0.00086 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEZ43140.1 - 0.00037 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEZ43140.1 - 0.00048 18.9 0.0 0.00091 18.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 KEZ43140.1 - 0.0011 18.0 0.1 0.0038 16.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KEZ43140.1 - 0.0013 18.3 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KEZ43140.1 - 0.0017 18.4 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 KEZ43140.1 - 0.0018 17.9 1.9 0.059 13.0 0.0 3.0 2 2 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 KEZ43140.1 - 0.0034 16.9 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KEZ43140.1 - 0.0036 17.0 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_23 PF13476.1 KEZ43140.1 - 0.0038 17.5 1.4 0.83 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KEZ43140.1 - 0.0048 16.7 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ43140.1 - 0.0049 16.4 1.2 0.016 14.8 0.0 2.2 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 KEZ43140.1 - 0.0052 16.3 0.0 0.043 13.4 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KEZ43140.1 - 0.0056 16.3 0.7 0.059 13.0 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 KEZ43140.1 - 0.0063 15.9 0.8 0.069 12.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEZ43140.1 - 0.0067 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KEZ43140.1 - 0.0073 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEZ43140.1 - 0.0075 16.5 0.0 0.028 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 KEZ43140.1 - 0.0088 15.4 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Cast PF10174.4 KEZ43140.1 - 0.0092 14.0 1.7 0.018 13.1 0.6 1.7 2 0 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone AAA_24 PF13479.1 KEZ43140.1 - 0.011 15.2 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KEZ43140.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 KEZ43140.1 - 0.026 13.6 1.4 0.45 9.5 0.0 2.8 3 0 0 3 3 3 0 KaiC Viral_Hsp90 PF03225.9 KEZ43140.1 - 0.037 12.3 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Sigma54_activat PF00158.21 KEZ43140.1 - 0.048 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KEZ43140.1 - 0.058 13.4 0.1 0.35 10.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 KEZ43140.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KEZ43140.1 - 0.16 10.7 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Y_phosphatase PF00102.22 KEZ43141.1 - 1.7e-45 155.1 0.0 3.9e-45 154.0 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEZ43141.1 - 0.00016 21.7 0.0 0.00059 19.9 0.0 2.0 2 1 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 KEZ43141.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KEZ43141.1 - 0.019 15.2 0.1 0.076 13.2 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Lipase_GDSL_2 PF13472.1 KEZ43142.1 - 3e-07 30.7 0.1 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ43142.1 - 5.8e-06 26.3 0.0 7.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-MYND PF01753.13 KEZ43143.1 - 5.7e-09 35.7 14.7 5.7e-09 35.7 10.2 2.2 2 0 0 2 2 2 1 MYND finger SET PF00856.23 KEZ43143.1 - 1.3e-08 35.3 0.1 3.8e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 SET domain Reo_sigmaC PF04582.7 KEZ43144.1 - 8e-05 21.9 5.2 8e-05 21.9 3.6 2.3 1 1 1 2 2 2 1 Reovirus sigma C capsid protein IncA PF04156.9 KEZ43144.1 - 0.00025 20.6 17.3 0.0011 18.6 1.6 3.1 1 1 2 3 3 3 2 IncA protein DivIC PF04977.10 KEZ43144.1 - 0.0019 17.6 0.4 0.0019 17.6 0.3 4.2 3 1 3 6 6 6 1 Septum formation initiator Filament PF00038.16 KEZ43144.1 - 0.0023 17.4 14.2 0.0047 16.4 2.0 2.7 1 1 2 3 3 3 1 Intermediate filament protein ERM PF00769.14 KEZ43144.1 - 0.0027 17.3 15.5 0.0029 17.1 9.2 2.0 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF641 PF04859.7 KEZ43144.1 - 0.0027 17.4 10.0 0.087 12.5 0.1 3.4 2 1 1 3 3 3 2 Plant protein of unknown function (DUF641) DUF972 PF06156.8 KEZ43144.1 - 0.0048 17.2 12.0 0.82 10.0 0.9 4.0 1 1 3 4 4 4 2 Protein of unknown function (DUF972) HALZ PF02183.13 KEZ43144.1 - 0.0051 16.5 0.9 21 4.9 0.0 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper AAA_13 PF13166.1 KEZ43144.1 - 0.0085 14.6 10.2 0.0058 15.1 3.4 2.2 1 1 1 2 2 2 1 AAA domain TMF_TATA_bd PF12325.3 KEZ43144.1 - 0.019 14.7 0.8 0.019 14.7 0.5 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.6 KEZ43144.1 - 0.021 14.7 8.6 0.46 10.4 0.6 4.8 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 KEZ43144.1 - 0.022 15.1 16.0 1.7 9.0 0.3 5.2 5 0 0 5 5 5 0 SlyX NPV_P10 PF05531.7 KEZ43144.1 - 0.026 14.7 7.6 1.5 9.1 0.4 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 KEZ43144.1 - 0.033 12.8 13.0 0.12 10.9 1.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.5 KEZ43144.1 - 0.036 14.1 9.9 0.61 10.1 1.6 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Hrs_helical PF12210.3 KEZ43144.1 - 0.038 14.2 1.4 0.14 12.4 1.0 2.0 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate EzrA PF06160.7 KEZ43144.1 - 0.052 11.7 8.4 0.056 11.6 0.2 2.8 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF948 PF06103.6 KEZ43144.1 - 0.063 13.1 3.8 0.63 9.9 1.2 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.8 KEZ43144.1 - 0.089 11.8 5.0 0.029 13.4 0.8 1.8 1 1 0 2 2 2 0 TMPIT-like protein Fez1 PF06818.10 KEZ43144.1 - 0.11 12.5 13.5 0.062 13.3 7.3 2.0 1 1 0 2 2 2 0 Fez1 DUF342 PF03961.8 KEZ43144.1 - 0.12 10.7 6.3 0.55 8.5 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) USP8_interact PF08941.5 KEZ43144.1 - 0.16 11.2 6.0 0.93 8.7 0.1 2.9 1 1 1 2 2 2 0 USP8 interacting DUF4618 PF15397.1 KEZ43144.1 - 0.19 11.0 9.1 0.14 11.5 1.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) WEMBL PF05701.6 KEZ43144.1 - 0.21 10.0 16.4 0.13 10.7 9.0 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light TBPIP PF07106.8 KEZ43144.1 - 0.24 10.9 12.5 1.6 8.2 1.0 3.4 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 KEZ43144.1 - 0.3 10.9 16.9 0.019 14.8 2.4 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YlqD PF11068.3 KEZ43144.1 - 0.31 11.0 6.9 0.48 10.4 0.5 2.8 1 1 1 2 2 2 0 YlqD protein DUF1664 PF07889.7 KEZ43144.1 - 0.34 10.7 9.1 0.045 13.5 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3972 PF13118.1 KEZ43144.1 - 0.35 10.9 0.1 0.35 10.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3972) Mnd1 PF03962.10 KEZ43144.1 - 0.37 10.4 13.9 2.3 7.8 1.5 3.3 1 1 2 3 3 3 0 Mnd1 family CCDC-167 PF15188.1 KEZ43144.1 - 0.38 10.7 9.8 1.2 9.1 0.0 3.5 3 1 1 4 4 3 0 Coiled-coil domain-containing protein 167 DUF3373 PF11853.3 KEZ43144.1 - 0.47 8.9 4.7 0.19 10.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) DUF489 PF04356.7 KEZ43144.1 - 0.56 9.7 3.6 0.41 10.2 0.1 2.3 2 1 1 3 3 2 0 Protein of unknown function (DUF489) GAS PF13851.1 KEZ43144.1 - 0.67 9.1 12.4 1.6 7.8 4.1 2.9 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 KEZ43144.1 - 0.75 8.7 11.4 0.14 11.1 4.0 2.1 1 1 2 3 3 3 0 Autophagy protein Apg6 Atg14 PF10186.4 KEZ43144.1 - 0.83 8.5 14.5 0.057 12.3 4.6 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 KEZ43144.1 - 0.92 9.5 8.1 14 5.6 0.0 4.4 3 1 1 4 4 4 0 bZIP transcription factor Macoilin PF09726.4 KEZ43144.1 - 0.94 7.6 12.4 0.71 8.0 7.6 1.6 1 1 0 1 1 1 0 Transmembrane protein ADIP PF11559.3 KEZ43144.1 - 1 9.2 19.1 0.19 11.6 1.0 3.6 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KEZ43144.1 - 1.1 7.0 10.2 2.3 5.9 1.7 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PilJ PF13675.1 KEZ43144.1 - 1.8 8.9 10.1 6.5 7.1 4.6 3.2 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term zf-C4H2 PF10146.4 KEZ43144.1 - 1.8 8.5 10.3 7.2 6.5 6.3 2.4 1 1 0 1 1 1 0 Zinc finger-containing protein COG2 PF06148.6 KEZ43144.1 - 2.1 8.2 10.8 0.2 11.5 0.9 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.14 KEZ43144.1 - 2.2 7.8 13.3 6.4 6.2 0.1 3.9 1 1 3 4 4 4 0 GrpE Sas10_Utp3 PF04000.10 KEZ43144.1 - 2.5 8.3 5.5 11 6.2 0.0 4.0 3 2 2 5 5 3 0 Sas10/Utp3/C1D family Laminin_II PF06009.7 KEZ43144.1 - 3.1 7.5 9.5 0.51 10.0 1.0 2.8 1 1 2 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.4 KEZ43144.1 - 3.2 7.9 8.4 13 6.0 0.2 3.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 KEZ43144.1 - 3.4 7.5 16.0 1.5 8.6 0.7 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Syntaxin-6_N PF09177.6 KEZ43144.1 - 4.1 7.8 9.8 2.3 8.6 2.1 3.4 1 1 3 4 4 4 0 Syntaxin 6, N-terminal AATF-Che1 PF13339.1 KEZ43144.1 - 6.2 6.9 16.2 0.39 10.8 0.7 3.2 1 1 2 3 3 3 0 Apoptosis antagonizing transcription factor Seryl_tRNA_N PF02403.17 KEZ43144.1 - 7.8 6.5 13.5 1.6 8.7 0.4 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 KEZ43144.1 - 8.7 6.1 13.4 2.9e+02 1.1 9.3 3.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Bap31 PF05529.7 KEZ43144.1 - 9.6 5.6 7.8 7.5 5.9 1.2 2.7 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like Kinesin-relat_1 PF12711.2 KEZ43144.1 - 9.7 6.6 9.6 8.3 6.8 0.1 3.4 1 1 2 4 4 3 0 Kinesin motor TPR_11 PF13414.1 KEZ43145.1 - 9.4e-29 98.8 2.4 6.8e-12 44.8 0.0 4.3 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 KEZ43145.1 - 1.2e-28 97.4 0.1 5.2e-07 28.9 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ43145.1 - 4.5e-26 88.6 2.9 1.1e-05 24.9 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ43145.1 - 7.5e-20 69.6 8.5 3.9e-05 23.8 0.0 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ43145.1 - 9.9e-19 67.5 6.5 2.8e-05 24.6 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ43145.1 - 2.1e-15 56.4 0.1 6.1e-07 29.2 0.0 4.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ43145.1 - 3.1e-15 56.2 3.7 0.00034 20.8 0.8 4.7 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ43145.1 - 4.8e-15 54.4 0.6 0.0022 18.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ43145.1 - 3.2e-13 48.4 0.0 0.066 13.0 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ43145.1 - 2.4e-12 45.6 1.8 0.048 13.4 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ43145.1 - 9.3e-10 38.4 0.4 0.0053 16.8 0.2 4.1 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ43145.1 - 1e-09 38.1 2.7 0.23 12.0 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ43145.1 - 4.1e-08 32.9 1.7 0.21 11.4 0.0 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 KEZ43145.1 - 5.1e-06 26.5 0.3 0.0042 17.1 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KEZ43145.1 - 1.2e-05 24.5 0.6 0.021 13.8 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 KEZ43145.1 - 0.012 15.4 0.0 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ43145.1 - 0.056 13.3 3.3 16 5.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KEZ43145.1 - 0.095 11.8 0.1 3.3 6.7 0.0 3.0 3 1 1 4 4 4 0 Coatomer epsilon subunit DED PF01335.16 KEZ43145.1 - 0.18 11.9 0.1 22 5.2 0.0 2.4 2 0 0 2 2 2 0 Death effector domain HLH PF00010.21 KEZ43146.1 - 2.1e-13 49.7 0.7 7.6e-13 47.9 0.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CENP-Q PF13094.1 KEZ43146.1 - 0.59 10.1 9.2 4.5 7.2 1.4 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 KEZ43146.1 - 0.82 9.2 5.4 1.3 8.5 3.7 1.2 1 0 0 1 1 1 0 IncA protein Tim17 PF02466.14 KEZ43147.1 - 4.8e-07 29.8 0.0 7.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BPD_transp_2 PF02653.11 KEZ43147.1 - 0.11 11.4 0.5 0.18 10.7 0.3 1.3 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component Ribosomal_S8e PF01201.17 KEZ43148.1 - 2.2e-35 121.6 4.0 2.7e-34 118.1 2.8 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 KEZ43148.1 - 2.8 7.2 6.6 12 5.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Ribosomal_S17 PF00366.15 KEZ43148.1 - 3.7 7.6 7.2 9.1 6.4 1.1 3.0 3 0 0 3 3 3 0 Ribosomal protein S17 Pkinase PF00069.20 KEZ43149.1 - 7.2e-44 149.8 0.0 1.1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43149.1 - 8.5e-22 77.4 0.0 1.3e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ43149.1 - 0.00016 21.5 0.7 0.52 10.0 0.0 3.5 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEZ43149.1 - 0.00048 19.1 0.0 0.0018 17.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PsaA_PsaB PF00223.14 KEZ43149.1 - 0.028 12.5 0.0 0.043 11.9 0.0 1.2 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_60s PF00428.14 KEZ43150.1 - 5.7e-28 97.1 12.1 6.5e-28 96.9 8.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein OCC1 PF15506.1 KEZ43150.1 - 1.4 8.8 9.1 0.72 9.7 4.3 1.9 2 0 0 2 2 2 0 OCC1 family Fungal_trans PF04082.13 KEZ43151.1 - 2.2e-10 39.8 1.1 3.2e-10 39.3 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Scytalone_dh PF02982.9 KEZ43152.1 - 2.2e-84 280.8 0.9 2.6e-84 280.6 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 KEZ43152.1 - 1.2e-07 31.6 1.2 1.7e-07 31.2 0.9 1.1 1 0 0 1 1 1 1 SnoaL-like domain zf-C2H2_4 PF13894.1 KEZ43154.1 - 0.0016 18.6 4.8 0.11 12.9 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger CpXC PF14353.1 KEZ43154.1 - 0.0069 16.3 2.6 0.015 15.2 1.8 1.5 1 0 0 1 1 1 1 CpXC protein zf-C2H2 PF00096.21 KEZ43154.1 - 0.0083 16.4 1.5 0.0083 16.4 1.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEZ43154.1 - 1.7 9.0 7.8 12 6.3 2.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain TerY-C PF15616.1 KEZ43154.1 - 8.2 6.3 8.5 2.5 8.0 3.8 1.6 2 0 0 2 2 2 0 TerY-C metal binding domain Annexin PF00191.15 KEZ43155.1 - 5.2e-71 234.4 4.9 3.2e-20 71.7 0.2 4.2 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.3 KEZ43155.1 - 0.0049 16.4 0.5 19 4.8 0.0 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3574) DUF3954 PF13128.1 KEZ43155.1 - 7.8 6.0 6.1 29 4.1 3.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3954) MFS_1 PF07690.11 KEZ43156.1 - 3.1e-31 108.3 40.6 1.3e-26 93.2 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KEZ43156.1 - 0.00082 19.3 0.6 0.00082 19.3 0.4 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) V-ATPase_H_N PF03224.9 KEZ43157.1 - 4.6e-70 236.2 0.3 1e-69 235.0 0.2 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KEZ43157.1 - 1.6e-38 131.2 0.1 5.1e-38 129.6 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 KEZ43157.1 - 0.095 12.9 2.8 0.95 9.7 0.0 3.4 3 1 0 3 3 3 0 HEAT repeats DUF2244 PF10003.4 KEZ43158.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF4131 PF13567.1 KEZ43158.1 - 0.87 8.9 2.8 44 3.4 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ribosomal_L6 PF00347.18 KEZ43159.1 - 2.3e-28 98.4 4.0 9e-14 51.7 0.3 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.10 KEZ43160.1 - 1.6e-131 437.1 1.2 1.8e-131 436.9 0.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KEZ43160.1 - 0.00054 19.7 0.1 0.13 12.0 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KEZ43160.1 - 0.073 13.1 0.1 0.3 11.1 0.1 2.1 1 1 1 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Nup160 PF11715.3 KEZ43161.1 - 9.3e-128 426.7 0.3 1.2e-127 426.3 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 KEZ43162.1 - 7.5e-137 454.3 0.0 9.4e-137 453.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KEZ43162.1 - 1.5e-12 47.3 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEZ43162.1 - 1.1e-06 27.9 0.0 1.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.16 KEZ43162.1 - 2.3e-06 26.9 0.0 3.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 KEZ43162.1 - 2.5e-06 27.5 0.9 6.8e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.10 KEZ43162.1 - 0.046 12.5 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 KEZ43162.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 PAXNEB protein Proteasome PF00227.21 KEZ43163.1 - 8.6e-30 103.4 0.3 1.9e-29 102.3 0.2 1.5 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.22 KEZ43164.1 - 6.6e-40 137.0 0.0 2.8e-39 134.9 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KEZ43164.1 - 5.3e-27 94.1 0.2 1.3e-26 92.9 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.16 KEZ43165.1 - 1.3e-25 90.0 14.8 5.6e-25 87.9 10.2 1.9 1 1 0 1 1 1 1 Cation efflux family Nucleoplasmin PF03066.10 KEZ43166.1 - 0.62 9.5 7.0 0.14 11.6 2.5 1.6 2 0 0 2 2 2 0 Nucleoplasmin Tom37_C PF11801.3 KEZ43166.1 - 0.97 9.2 5.3 2.9 7.7 3.7 1.8 1 0 0 1 1 1 0 Tom37 C-terminal domain Peptidase_S9 PF00326.16 KEZ43167.1 - 9.4e-53 178.5 0.0 1.5e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ43167.1 - 3.3e-10 39.8 0.0 5.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ43167.1 - 2e-07 31.1 0.1 5.7e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KEZ43167.1 - 0.00041 19.9 0.0 0.002 17.7 0.0 2.2 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 KEZ43167.1 - 0.00089 17.8 0.0 0.0046 15.4 0.0 1.9 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) NuA4 PF09340.5 KEZ43168.1 - 3.3e-21 74.7 0.2 3.3e-21 74.7 0.2 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF3629 PF12302.3 KEZ43168.1 - 0.01 15.2 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF1465 PF07323.7 KEZ43168.1 - 0.03 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) PspB PF06667.7 KEZ43168.1 - 0.072 13.0 1.4 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 Phage shock protein B Calreticulin PF00262.13 KEZ43169.1 - 8.2e-163 541.2 18.3 8.2e-163 541.2 12.7 1.4 2 0 0 2 2 2 1 Calreticulin family AF-4 PF05110.8 KEZ43170.1 - 2.9 5.6 13.2 2.8 5.6 9.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dynamin_M PF01031.15 KEZ43171.1 - 1.1e-113 378.8 0.0 2.6e-113 377.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KEZ43171.1 - 6.9e-56 188.6 0.0 2.9e-55 186.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KEZ43171.1 - 1e-30 105.4 1.1 1e-30 105.4 0.8 2.2 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KEZ43171.1 - 0.00031 20.6 0.0 0.0012 18.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ43171.1 - 0.022 15.2 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 KEZ43171.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle CHCH PF06747.8 KEZ43172.1 - 0.0003 20.6 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KEZ43172.1 - 0.032 14.0 0.5 0.058 13.1 0.4 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KEZ43172.1 - 0.063 13.3 1.5 0.84 9.7 1.3 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 KEZ43172.1 - 0.17 11.7 1.5 6.8 6.6 0.1 2.2 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) LIM PF00412.17 KEZ43173.1 - 1.3e-08 34.7 6.3 1.3e-08 34.7 4.4 2.5 3 0 0 3 3 3 1 LIM domain DUF2321 PF10083.4 KEZ43173.1 - 0.042 13.3 0.6 0.042 13.3 0.4 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Nudix_N_2 PF14803.1 KEZ43173.1 - 0.21 11.3 8.2 0.81 9.4 0.6 3.3 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.2 KEZ43173.1 - 0.86 9.4 12.3 6.5 6.6 8.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon Nup84_Nup100 PF04121.8 KEZ43174.1 - 4.2e-46 156.9 0.0 4.6e-45 153.5 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Mod_r PF07200.8 KEZ43174.1 - 1.8e-05 24.6 0.5 4.5e-05 23.4 0.4 1.7 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein F-box PF00646.28 KEZ43175.1 - 4.5e-06 26.1 1.0 1e-05 25.0 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEZ43175.1 - 0.0048 16.6 0.4 0.023 14.4 0.3 2.2 1 0 0 1 1 1 1 F-box-like V-ATPase_C PF03223.10 KEZ43176.1 - 4.2e-87 292.4 0.1 7.9e-70 235.6 0.1 2.0 1 1 1 2 2 2 2 V-ATPase subunit C TFIID_20kDa PF03847.8 KEZ43176.1 - 0.12 12.6 0.1 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A E1-E2_ATPase PF00122.15 KEZ43178.1 - 7e-65 218.2 5.1 1.3e-64 217.3 3.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ43178.1 - 3.2e-31 108.2 2.0 3.2e-31 108.2 1.4 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ43178.1 - 7.3e-28 98.4 0.0 6.2e-23 82.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ43178.1 - 4.5e-20 71.4 0.0 8.6e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ43178.1 - 4.4e-12 46.5 0.0 1.2e-11 45.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ43178.1 - 5.6e-11 41.7 0.0 1.7e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEZ43178.1 - 4.9e-06 26.3 0.3 0.00017 21.2 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.27 KEZ43179.1 - 6.3e-74 241.4 22.3 7e-12 44.7 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KEZ43179.1 - 2.5e-05 22.6 2.2 0.13 10.4 0.1 4.0 2 2 1 3 3 3 2 Nucleoporin Nup120/160 F-box-like PF12937.2 KEZ43179.1 - 0.0046 16.6 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like NADH-u_ox-rdase PF10785.4 KEZ43180.1 - 5.3e-34 116.3 0.3 8.3e-34 115.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KEZ43180.1 - 2.6e-33 113.5 0.1 3.8e-33 113.0 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.7 KEZ43181.1 - 2e-27 94.6 0.2 3e-27 94.0 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 bZIP_2 PF07716.10 KEZ43182.1 - 8.8e-08 31.8 17.0 2e-07 30.6 11.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KEZ43182.1 - 0.00082 19.2 19.9 0.0021 17.9 13.8 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KEZ43182.1 - 0.0053 17.0 11.9 0.011 16.0 8.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6 PF04111.7 KEZ43182.1 - 0.2 10.6 2.6 0.27 10.2 1.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KEZ43182.1 - 0.44 10.1 4.6 0.68 9.4 3.2 1.3 1 0 0 1 1 1 0 IncA protein TMEM247 PF15444.1 KEZ43182.1 - 0.66 9.7 4.2 0.64 9.8 1.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 247 RR_TM4-6 PF06459.7 KEZ43182.1 - 6.6 6.5 7.5 11 5.8 5.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Snf7 PF03357.16 KEZ43183.1 - 2.3e-07 30.3 23.6 2.3e-07 30.3 16.4 1.5 1 1 1 2 2 2 1 Snf7 ASL_C PF08328.6 KEZ43183.1 - 0.012 15.4 5.9 0.26 11.1 2.4 2.4 1 1 0 2 2 2 0 Adenylosuccinate lyase C-terminal Ist1 PF03398.9 KEZ43183.1 - 0.017 14.5 6.5 0.039 13.3 4.5 1.7 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway SATase_N PF06426.9 KEZ43183.1 - 1.1 9.5 7.8 4.8 7.4 5.4 2.2 1 1 0 1 1 1 0 Serine acetyltransferase, N-terminal DUF1451 PF07295.6 KEZ43183.1 - 2.8 7.6 9.7 0.77 9.5 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Dynactin_p62 PF05502.8 KEZ43183.1 - 4.7 5.8 11.2 5.2 5.7 7.7 1.1 1 0 0 1 1 1 0 Dynactin p62 family DSHCT PF08148.7 KEZ43184.1 - 1.2e-61 207.1 0.7 2.2e-61 206.2 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Transket_pyr PF02779.19 KEZ43184.1 - 3.6e-45 153.6 0.0 7.8e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KEZ43184.1 - 1.1e-32 112.5 0.0 2.9e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DEAD PF00270.24 KEZ43184.1 - 1.1e-19 70.5 0.0 4.5e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ43184.1 - 6.6e-06 25.8 0.7 1.4e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Syntaxin PF00804.20 KEZ43184.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 Syntaxin Sterol_MT_C PF08498.5 KEZ43185.1 - 3.5e-30 103.7 0.1 5.7e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KEZ43185.1 - 8.7e-21 74.2 0.0 1.8e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43185.1 - 3.1e-18 65.8 0.0 4.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ43185.1 - 2.2e-14 53.4 0.0 4.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ43185.1 - 2.3e-13 50.3 0.0 4.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ43185.1 - 5.7e-12 46.2 0.0 1.6e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ43185.1 - 1.5e-11 43.9 0.0 3.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KEZ43185.1 - 1.6e-11 43.8 0.1 2.3e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KEZ43185.1 - 4.1e-11 43.2 0.4 2.1e-10 40.9 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ43185.1 - 1.5e-09 37.8 0.0 4.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KEZ43185.1 - 9.3e-06 25.2 0.1 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KEZ43185.1 - 3.4e-05 23.2 0.0 7.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KEZ43185.1 - 4.8e-05 22.9 0.0 0.00012 21.6 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 KEZ43185.1 - 0.00069 18.8 0.0 0.002 17.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 KEZ43185.1 - 0.0031 18.3 0.1 0.02 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KEZ43185.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KEZ43185.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KEZ43185.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 KEZ43185.1 - 0.046 13.2 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 KEZ43185.1 - 0.048 12.8 0.2 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase TehB PF03848.9 KEZ43185.1 - 0.056 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB RRM_5 PF13893.1 KEZ43186.1 - 1.2e-09 37.8 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ43186.1 - 4.6e-08 32.5 0.0 7.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ43186.1 - 5.6e-06 26.2 0.0 9.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ43186.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEZ43186.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Complex1_LYR PF05347.10 KEZ43187.1 - 1.3e-05 24.8 2.6 2.2e-05 24.1 0.5 1.9 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEZ43187.1 - 1.7e-05 24.9 0.6 2.8e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DnaJ PF00226.26 KEZ43188.1 - 3.6e-19 68.2 1.5 3.6e-19 68.2 1.1 2.4 2 0 0 2 2 2 1 DnaJ domain PAN_1 PF00024.21 KEZ43189.1 - 0.04 13.6 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.1 KEZ43189.1 - 0.078 12.6 2.8 0.13 11.9 1.9 1.3 1 0 0 1 1 1 0 PAN domain DUF1691 PF07950.6 KEZ43190.1 - 2e-38 130.6 5.9 5.2e-24 84.2 1.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.3 KEZ43191.1 - 2.7e-05 24.1 3.0 4.7e-05 23.4 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ43191.1 - 0.001 19.1 0.9 0.0017 18.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEZ43191.1 - 0.0057 16.8 0.2 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger HlyD_2 PF12700.2 KEZ43191.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein zf-C2H2 PF00096.21 KEZ43191.1 - 0.021 15.1 1.0 0.039 14.3 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 KEZ43191.1 - 0.085 12.9 0.7 0.13 12.3 0.5 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GRIP PF01465.15 KEZ43192.1 - 1.3e-15 56.6 0.0 2.8e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 GRIP domain AAA_13 PF13166.1 KEZ43192.1 - 0.00022 19.8 18.1 0.00022 19.8 12.5 5.4 3 1 2 5 5 5 2 AAA domain MscS_porin PF12795.2 KEZ43192.1 - 0.00063 19.1 22.4 0.00063 19.1 15.5 6.4 3 1 3 6 6 6 2 Mechanosensitive ion channel porin domain Phage_GP20 PF06810.6 KEZ43192.1 - 0.00085 18.7 6.6 0.00085 18.7 4.6 10.5 3 2 6 10 10 10 3 Phage minor structural protein GP20 ERM PF00769.14 KEZ43192.1 - 0.003 17.1 19.0 0.003 17.1 13.2 7.5 3 2 5 8 8 8 1 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 KEZ43192.1 - 0.043 12.9 57.7 0.039 13.1 2.7 7.6 4 3 1 8 8 8 0 Reovirus sigma C capsid protein IncA PF04156.9 KEZ43192.1 - 0.15 11.6 162.4 0.18 11.3 14.4 7.9 2 2 3 6 6 6 0 IncA protein GAS PF13851.1 KEZ43192.1 - 5.3 6.1 152.8 0.28 10.3 14.0 8.4 4 3 3 7 7 7 0 Growth-arrest specific micro-tubule binding DUF2296 PF10058.4 KEZ43193.1 - 6.7e-18 64.1 0.1 1.2e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF485 PF04341.7 KEZ43193.1 - 0.15 11.7 0.3 0.26 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 zf-RanBP PF00641.13 KEZ43193.1 - 0.25 10.4 2.9 0.18 10.9 0.3 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF605 PF04652.11 KEZ43193.1 - 1.3 8.3 5.4 2 7.7 3.7 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KEZ43194.1 - 1e-41 142.8 0.6 8.4e-25 87.3 0.3 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43194.1 - 1.7e-14 53.5 0.4 5.7e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.6 KEZ43195.1 - 2.2e-11 43.0 0.0 4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Brr6_like_C_C PF10104.4 KEZ43196.1 - 2.9e-26 91.5 1.1 3.8e-26 91.2 0.7 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.13 KEZ43197.1 - 4.2e-23 81.5 0.3 7.8e-23 80.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ43197.1 - 1e-07 31.7 13.1 1.8e-07 30.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex16 PF08610.5 KEZ43198.1 - 2.2e-102 342.5 0.0 2.5e-102 342.3 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF2984 PF11203.3 KEZ43198.1 - 0.014 15.4 0.2 0.11 12.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2984) zf-met PF12874.2 KEZ43199.1 - 0.035 14.3 4.6 1.1 9.5 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEZ43199.1 - 0.11 12.8 18.8 0.33 11.3 1.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ43199.1 - 2.4 8.6 15.6 0.089 13.1 0.8 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type HLH PF00010.21 KEZ43200.1 - 8.2e-20 70.2 0.2 1.4e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.4 KEZ43200.1 - 0.069 12.6 6.9 0.11 11.9 4.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DGF-1_C PF11040.3 KEZ43200.1 - 0.14 12.0 2.2 0.34 10.8 1.5 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SNF2_N PF00176.18 KEZ43201.1 - 2.5e-60 203.8 0.1 3.9e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KEZ43201.1 - 3.5e-08 33.1 0.0 7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEZ43201.1 - 1.1e-06 28.5 0.1 2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEZ43201.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain NACHT PF05729.7 KEZ43202.1 - 6.1e-12 45.5 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ43202.1 - 6.1e-08 32.8 0.0 2.5e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ43202.1 - 7.2e-07 29.3 0.0 7.2e-07 29.3 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain KAP_NTPase PF07693.9 KEZ43202.1 - 7e-05 21.9 0.2 0.058 12.3 0.1 2.6 2 0 0 2 2 2 2 KAP family P-loop domain AAA_14 PF13173.1 KEZ43202.1 - 0.0016 18.3 0.5 0.018 14.9 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA PF00004.24 KEZ43202.1 - 0.0023 18.1 3.0 0.011 15.9 0.0 3.4 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ43202.1 - 0.0028 18.4 0.3 0.022 15.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KEZ43202.1 - 0.0067 15.3 0.0 0.0067 15.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 KEZ43202.1 - 0.011 15.4 0.0 0.052 13.2 0.0 2.1 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.15 KEZ43202.1 - 0.011 15.3 0.0 0.035 13.7 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 KEZ43202.1 - 0.013 14.9 0.5 0.11 11.9 0.3 2.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEZ43202.1 - 0.014 14.8 0.1 0.074 12.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.1 KEZ43202.1 - 0.023 14.4 2.4 0.18 11.5 0.0 2.8 3 0 0 3 3 2 0 Part of AAA domain KTI12 PF08433.5 KEZ43202.1 - 0.023 13.8 0.0 0.048 12.8 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 KEZ43202.1 - 0.025 14.4 0.0 0.083 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEZ43202.1 - 0.036 14.3 0.6 0.14 12.4 0.0 2.3 3 0 0 3 3 1 0 AAA domain KaiC PF06745.8 KEZ43202.1 - 0.04 13.0 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 KEZ43202.1 - 0.047 12.7 0.1 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 KEZ43202.1 - 0.059 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEZ43202.1 - 0.075 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 KEZ43202.1 - 0.083 12.6 8.2 1.7 8.4 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function DUF87 cobW PF02492.14 KEZ43202.1 - 0.084 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.23 KEZ43203.1 - 6e-75 252.1 0.0 7.7e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ43203.1 - 7.7e-12 45.9 0.3 1.6e-11 45.0 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 KEZ43204.1 - 3.2e-05 22.9 0.8 0.16 10.8 0.0 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain APH PF01636.18 KEZ43205.1 - 3.1e-07 30.3 0.0 5.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ43205.1 - 0.008 15.7 0.2 0.015 14.8 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF3049 PF11250.3 KEZ43205.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) WD40 PF00400.27 KEZ43206.1 - 6e-28 95.6 3.5 1.9e-07 30.6 0.3 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Prim-Pol PF09250.6 KEZ43206.1 - 0.016 15.2 0.6 0.11 12.4 0.2 2.1 1 1 1 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal WD40 PF00400.27 KEZ43207.1 - 3.8e-14 51.9 6.8 0.021 14.7 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat SRR1 PF07985.7 KEZ43208.1 - 0.0055 16.6 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 SRR1 Ribosomal_60s PF00428.14 KEZ43208.1 - 0.15 12.4 8.5 0.37 11.2 5.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PFU PF09070.6 KEZ43209.1 - 2.6e-43 146.7 0.1 4.6e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KEZ43209.1 - 8.2e-43 142.7 11.0 1.6e-07 30.9 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 KEZ43209.1 - 8.9e-33 113.2 0.0 1.2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 PUL domain AAA_12 PF13087.1 KEZ43211.1 - 1.9e-33 115.5 0.0 4.2e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ43211.1 - 1.8e-23 83.3 0.0 5e-23 81.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ43211.1 - 1.4e-10 40.7 1.2 1.3e-08 34.4 0.0 3.0 2 1 1 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KEZ43211.1 - 7.8e-09 35.3 0.0 3.4e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KEZ43211.1 - 4.8e-05 22.9 0.0 0.0049 16.4 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KEZ43211.1 - 0.012 14.8 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.16 KEZ43211.1 - 0.015 14.5 0.0 8.3 5.5 0.0 3.1 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain ResIII PF04851.10 KEZ43211.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEZ43211.1 - 0.17 10.8 0.1 0.65 8.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF2457 PF10446.4 KEZ43211.1 - 2.3 6.8 7.0 4.2 5.9 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NmrA PF05368.8 KEZ43212.1 - 4.9e-15 55.4 0.0 5.6e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ43212.1 - 8.8e-15 55.1 0.0 9.9e-15 55.0 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KEZ43212.1 - 7.5e-06 25.9 0.2 9.2e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEZ43212.1 - 8.1e-06 25.4 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KEZ43212.1 - 2e-05 23.7 0.1 2.3e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KEZ43212.1 - 0.00024 20.8 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEZ43212.1 - 0.00083 18.3 0.0 0.0014 17.5 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 KEZ43212.1 - 0.002 18.5 0.1 0.0042 17.4 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 KEZ43212.1 - 0.004 17.0 0.3 0.0059 16.5 0.2 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KEZ43212.1 - 0.0062 15.4 0.0 0.081 11.8 0.0 1.9 1 1 1 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KEZ43212.1 - 0.013 14.2 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 KEZ43212.1 - 0.016 15.7 0.3 0.16 12.5 0.1 2.0 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.7 KEZ43212.1 - 0.055 12.3 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 KEZ43212.1 - 0.058 13.7 0.1 0.086 13.1 0.1 1.3 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 KEZ43212.1 - 0.097 12.6 0.1 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ank_2 PF12796.2 KEZ43213.1 - 1.9e-85 281.3 7.2 2.4e-19 69.4 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43213.1 - 1.8e-67 219.9 6.7 2.4e-08 33.3 0.0 11.4 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 KEZ43213.1 - 2e-52 174.0 3.4 2.7e-11 43.3 0.0 8.8 3 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43213.1 - 2.4e-42 138.6 2.3 0.0012 18.8 0.0 10.9 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KEZ43213.1 - 1.8e-40 136.6 6.2 1.3e-07 31.8 0.0 9.7 4 2 5 9 9 9 9 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ43213.1 - 6.9e-12 45.3 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KEZ43213.1 - 0.00032 20.6 0.1 0.013 15.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEZ43213.1 - 0.00072 19.6 0.0 0.0056 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ43213.1 - 0.0048 16.9 3.5 0.015 15.3 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 KEZ43213.1 - 0.0075 16.4 0.0 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KEZ43213.1 - 0.019 14.6 0.0 0.92 9.1 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DHQ_synthase PF01761.15 KEZ43214.1 - 5.7e-58 195.8 0.0 9e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase ADH_N PF08240.7 KEZ43215.1 - 6.7e-23 80.5 0.5 1.5e-22 79.3 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ43215.1 - 5.8e-15 54.9 0.0 9.8e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ43215.1 - 0.00029 21.7 0.0 0.00066 20.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KEZ43215.1 - 0.0036 16.3 0.1 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Ank_2 PF12796.2 KEZ43217.1 - 6.2e-38 129.0 0.9 7.7e-15 55.0 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43217.1 - 2.6e-30 102.6 1.3 4.4e-08 32.5 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KEZ43217.1 - 2.6e-22 76.6 0.3 2.4e-05 24.1 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KEZ43217.1 - 4e-22 78.1 2.0 1.3e-08 35.1 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ43217.1 - 6.3e-21 73.9 1.1 7.9e-06 25.9 0.0 4.7 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Sugar_tr PF00083.19 KEZ43218.1 - 1.8e-53 181.7 29.3 4.8e-29 101.2 9.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43218.1 - 4.5e-07 28.8 31.9 4.5e-07 28.8 22.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.18 KEZ43219.1 - 1.4e-62 211.6 0.9 2e-62 211.1 0.6 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEZ43219.1 - 0.00013 21.4 0.2 0.038 13.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Zn_clus PF00172.13 KEZ43220.1 - 9.7e-08 31.7 13.5 1.8e-07 30.9 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEZ43220.1 - 1.4e-05 23.9 0.3 1.8e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGAP1 PF07819.8 KEZ43222.1 - 7.1e-08 32.3 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein WD40 PF00400.27 KEZ43222.1 - 0.00046 19.9 0.1 8.7 6.3 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Cutinase PF01083.17 KEZ43222.1 - 0.0015 18.3 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 KEZ43222.1 - 0.0016 18.3 0.5 0.0089 15.9 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.7 KEZ43222.1 - 0.0096 15.5 0.0 0.032 13.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 KEZ43222.1 - 0.015 15.0 0.1 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 KEZ43222.1 - 0.027 13.7 0.0 0.061 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.1 KEZ43222.1 - 0.044 13.7 0.1 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain LCAT PF02450.10 KEZ43222.1 - 0.073 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Fructosamin_kin PF03881.9 KEZ43223.1 - 3.6e-17 62.2 0.0 4.4e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase Glyco_hydro_61 PF03443.9 KEZ43224.1 - 6.8e-35 120.8 0.0 1.4e-34 119.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 FAD-oxidase_C PF02913.14 KEZ43226.1 - 7.1e-59 199.1 0.1 1.1e-58 198.4 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEZ43226.1 - 3.6e-41 139.9 0.0 8.8e-41 138.6 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain ANF_receptor PF01094.23 KEZ43226.1 - 0.027 13.2 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region SLA_LP_auto_ag PF05889.8 KEZ43226.1 - 0.086 11.2 0.2 0.21 10.0 0.1 1.6 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Peptidase_S15 PF02129.13 KEZ43227.1 - 1.5e-32 113.0 0.9 6.3e-26 91.3 1.4 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KEZ43227.1 - 2.1e-22 80.0 0.0 3.1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KEZ43227.1 - 0.00018 21.4 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ43227.1 - 0.016 14.4 0.3 0.028 13.6 0.2 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ43227.1 - 0.053 13.2 0.1 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family HET PF06985.6 KEZ43228.1 - 9.1e-23 80.9 4.9 1.1e-21 77.4 3.4 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.28 KEZ43229.1 - 0.047 13.3 0.1 0.18 11.4 0.1 2.0 1 0 0 1 1 1 0 F-box domain Ank_2 PF12796.2 KEZ43230.1 - 2.3e-185 601.5 30.5 2.6e-20 72.5 0.1 14.4 2 1 8 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43230.1 - 2.6e-154 494.0 47.7 1.2e-08 34.3 0.0 28.2 29 0 0 29 29 29 25 Ankyrin repeat Ank_4 PF13637.1 KEZ43230.1 - 7.7e-120 389.4 24.9 9.1e-11 41.9 0.0 19.0 8 5 10 20 20 20 19 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43230.1 - 5.9e-117 369.7 25.6 8.6e-06 25.5 0.0 28.5 28 0 0 28 28 28 26 Ankyrin repeat Ank_5 PF13857.1 KEZ43230.1 - 2.1e-100 326.4 37.0 1.2e-09 38.0 0.1 19.2 6 4 12 20 20 20 18 Ankyrin repeats (many copies) HET PF06985.6 KEZ43230.1 - 4.5e-29 101.3 0.0 1.2e-28 100.0 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.1 KEZ43231.1 - 1e-18 67.5 0.0 1.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43231.1 - 1.8e-07 30.8 0.0 7.2e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43231.1 - 6.6e-07 29.7 0.0 1.1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ43231.1 - 4e-06 27.3 0.0 4.1e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ43231.1 - 1.1e-05 25.8 0.0 4.6e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ43231.1 - 1.3e-05 25.4 0.0 2.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ43231.1 - 0.002 17.5 0.0 0.0061 16.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 KEZ43231.1 - 0.013 14.7 0.1 0.076 12.1 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_4 PF02390.12 KEZ43231.1 - 0.032 13.2 0.0 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 KEZ43231.1 - 0.081 12.0 0.0 1 8.4 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ43231.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KEZ43231.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) E1-E2_ATPase PF00122.15 KEZ43232.1 - 6.9e-42 143.0 4.7 7.6e-42 142.9 0.1 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ43232.1 - 6.8e-19 69.1 0.0 1.6e-18 67.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ43232.1 - 1.4e-14 54.7 0.1 2.5e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ43232.1 - 1.6e-10 40.2 0.0 3.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 KEZ43232.1 - 1.4e-08 34.4 18.2 8.2e-08 31.9 6.6 3.5 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KEZ43232.1 - 2.4e-08 33.8 0.0 5.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF1129 PF06570.6 KEZ43232.1 - 0.13 11.5 0.1 0.13 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MFS_1 PF07690.11 KEZ43233.1 - 2.2e-31 108.8 48.1 5.6e-30 104.2 33.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43233.1 - 9.5e-09 34.3 16.5 9.5e-09 34.3 11.4 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter DUF676 PF05057.9 KEZ43235.1 - 0.042 13.1 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 KEZ43235.1 - 0.058 12.3 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 KEZ43235.1 - 0.069 13.0 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short_C2 PF13561.1 KEZ43236.1 - 2.1e-34 119.3 0.0 2.5e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ43236.1 - 7.2e-30 104.1 0.8 7.6e-30 104.0 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ43236.1 - 1.4e-12 47.6 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ43236.1 - 1.2e-05 24.8 0.0 7.5e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEZ43236.1 - 0.047 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KEZ43236.1 - 0.076 13.0 0.5 0.22 11.5 0.3 1.9 1 1 0 1 1 1 0 NADH(P)-binding DUF3726 PF12525.3 KEZ43236.1 - 0.079 12.7 0.1 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) zf-C2H2_4 PF13894.1 KEZ43237.1 - 2.3 8.7 9.0 1.2 9.6 0.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_S8 PF00082.17 KEZ43238.1 - 3.9e-15 55.7 0.0 6.8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Subtilase family RAP-1 PF03085.10 KEZ43238.1 - 0.053 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-RING_2 PF13639.1 KEZ43241.1 - 5.9e-06 26.0 12.5 9.4e-06 25.3 8.7 1.3 1 0 0 1 1 1 1 Ring finger domain APH PF01636.18 KEZ43241.1 - 1.6e-05 24.7 0.0 5.1e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family FANCL_C PF11793.3 KEZ43241.1 - 0.00045 20.1 9.3 0.00084 19.2 6.4 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KEZ43241.1 - 0.0068 16.2 4.7 0.013 15.3 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KEZ43241.1 - 0.084 12.9 7.9 0.15 12.2 5.5 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 KEZ43241.1 - 1.9 8.2 12.5 3.1 7.6 8.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEZ43241.1 - 3.9 7.2 9.5 6.6 6.4 6.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEZ43241.1 - 4.1 7.0 11.7 7.3 6.2 8.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Na_H_Exchanger PF00999.16 KEZ43242.1 - 1.5e-63 214.5 47.8 2.2e-63 214.0 33.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Aldo_ket_red PF00248.16 KEZ43243.1 - 1.4e-60 204.5 0.0 1.6e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RAG2 PF03089.9 KEZ43243.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Recombination activating protein 2 DUF3129 PF11327.3 KEZ43244.1 - 3.1e-10 40.1 0.0 3.5e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) MFS_1 PF07690.11 KEZ43245.1 - 3.7e-18 65.3 19.9 7.3e-17 61.1 5.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 KEZ43245.1 - 0.06 12.7 7.7 1.2 8.5 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) FAD_binding_4 PF01565.18 KEZ43246.1 - 3.7e-29 100.9 0.0 5.4e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KEZ43246.1 - 2.2e-14 53.3 0.0 3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF89 PF01937.14 KEZ43247.1 - 0.087 11.5 0.4 0.24 10.1 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF89 HNH_2 PF13391.1 KEZ43249.1 - 2.1e-06 27.3 0.0 1.9e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 HNH endonuclease CTP_synth_N PF06418.9 KEZ43250.1 - 9.7e-106 352.8 0.4 1.4e-105 352.3 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KEZ43250.1 - 3.8e-57 192.8 0.0 5.6e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KEZ43250.1 - 2e-07 30.6 0.0 6.1e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 KEZ43250.1 - 8.2e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KEZ43250.1 - 0.1 11.6 0.9 0.16 10.9 0.6 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase HET PF06985.6 KEZ43251.1 - 9.2e-39 132.7 0.1 5.6e-35 120.5 0.0 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 KEZ43252.1 - 2.2e-30 105.9 0.0 2.4e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 KEZ43252.1 - 7e-10 38.5 0.0 0.00015 20.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KEZ43252.1 - 2.2e-08 33.3 0.1 0.0022 16.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ43252.1 - 2.8e-06 27.2 0.2 1.3e-05 25.0 0.2 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ43252.1 - 3.7e-06 27.1 0.2 1.1e-05 25.6 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ43252.1 - 4.1e-05 22.2 0.5 0.0011 17.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KEZ43252.1 - 0.00013 22.3 1.1 0.0063 16.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ43252.1 - 0.00032 19.8 0.3 0.0018 17.3 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KEZ43252.1 - 0.00056 18.8 1.2 0.0011 17.9 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KEZ43252.1 - 0.00061 18.8 0.7 0.2 10.5 0.3 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ43252.1 - 0.00089 19.1 0.6 0.0019 18.1 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEZ43252.1 - 0.005 15.5 0.2 0.0078 14.8 0.1 1.4 1 1 0 1 1 1 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 KEZ43252.1 - 0.014 14.9 0.2 0.014 14.9 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 KEZ43252.1 - 0.022 14.5 2.3 2.6 7.8 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 KEZ43252.1 - 0.19 10.5 2.9 0.13 11.0 0.6 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A HeLo PF14479.1 KEZ43253.1 - 1.1e-34 120.1 2.4 1.7e-34 119.4 1.7 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation UQ_con PF00179.21 KEZ43253.1 - 0.089 12.2 0.0 0.81 9.1 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Ank_2 PF12796.2 KEZ43254.1 - 3.2e-78 258.1 5.2 5.4e-15 55.5 0.0 7.3 3 1 7 10 10 10 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43254.1 - 1.1e-43 144.9 14.9 3e-06 26.7 0.0 12.9 13 1 1 14 14 14 9 Ankyrin repeat Ank_4 PF13637.1 KEZ43254.1 - 6e-37 125.3 0.1 3.9e-06 27.2 0.0 9.6 6 3 4 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43254.1 - 2.7e-33 110.6 2.4 4.9e-05 23.1 0.0 12.4 14 1 1 15 15 15 7 Ankyrin repeat Ank_5 PF13857.1 KEZ43254.1 - 4.5e-30 102.9 4.8 0.00015 21.8 0.0 9.7 5 3 3 9 9 9 6 Ankyrin repeats (many copies) Clr5 PF14420.1 KEZ43254.1 - 1.7e-08 34.1 0.5 3.4e-08 33.2 0.3 1.5 1 0 0 1 1 1 1 Clr5 domain Shigella_OspC PF06128.6 KEZ43254.1 - 0.018 14.5 0.0 1.5 8.2 0.0 3.1 3 1 0 3 3 3 0 Shigella flexneri OspC protein Dicty_CAR PF05462.6 KEZ43255.1 - 1.4e-07 30.7 7.1 1.4e-07 30.7 4.9 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KEZ43255.1 - 0.28 10.7 10.9 0.015 14.8 3.9 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 NAD_binding_10 PF13460.1 KEZ43256.1 - 1.2e-17 64.5 0.5 1.8e-17 63.9 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEZ43256.1 - 1.2e-17 63.9 0.0 2.2e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 KEZ43256.1 - 9.8e-06 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 KEZ43256.1 - 0.00018 21.9 0.2 0.00048 20.5 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KEZ43256.1 - 0.0014 18.9 0.3 0.004 17.4 0.2 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KEZ43256.1 - 0.0055 16.3 0.9 0.019 14.6 0.6 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ43256.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KEZ43256.1 - 0.015 15.2 1.6 0.06 13.2 1.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase CoA_binding PF02629.14 KEZ43256.1 - 0.02 15.4 0.1 0.52 10.8 0.1 2.6 2 1 0 2 2 2 0 CoA binding domain DapB_N PF01113.15 KEZ43256.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.11 KEZ43256.1 - 0.11 11.9 0.3 0.26 10.7 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoA_binding_2 PF13380.1 KEZ43256.1 - 0.12 12.5 1.7 0.18 12.0 0.4 2.0 2 1 0 2 2 2 0 CoA binding domain CBM_4_9 PF02018.12 KEZ43257.1 - 1.3e-06 28.4 0.5 0.016 15.2 0.1 2.3 2 0 0 2 2 2 2 Carbohydrate binding domain adh_short PF00106.20 KEZ43258.1 - 4.8e-19 68.8 0.3 7.7e-19 68.2 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ43258.1 - 3.7e-09 36.4 0.3 6.2e-09 35.7 0.1 1.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEZ43261.1 - 4e-09 36.6 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase AAA PF00004.24 KEZ43261.1 - 3.9e-08 33.5 3.1 1.9e-05 24.8 2.1 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEZ43261.1 - 0.035 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein FMO-like PF00743.14 KEZ43262.1 - 1.3e-46 158.9 0.0 4.6e-44 150.5 0.0 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEZ43262.1 - 3.4e-19 69.7 0.0 4.1e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 KEZ43262.1 - 2.1e-13 50.0 0.0 2.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain K_oxygenase PF13434.1 KEZ43262.1 - 1.8e-08 33.6 0.0 3.3e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ43262.1 - 0.00088 19.0 0.1 0.22 11.2 0.0 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KEZ43262.1 - 0.034 14.1 0.1 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ43262.1 - 0.16 12.3 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3638 PF12340.3 KEZ43263.1 - 8e-94 312.9 0.6 1.5e-93 311.9 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KEZ43263.1 - 3.8e-15 54.7 0.2 8.6e-15 53.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) AAA_19 PF13245.1 KEZ43263.1 - 0.069 12.9 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Ank_2 PF12796.2 KEZ43264.1 - 7.4e-41 138.3 0.0 1.1e-14 54.4 0.0 6.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43264.1 - 2.5e-33 112.1 4.4 4.7e-07 29.3 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KEZ43264.1 - 1.2e-32 111.1 7.0 8.5e-10 38.5 0.0 6.7 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ43264.1 - 1.4e-27 95.5 2.4 6.4e-07 29.7 0.0 8.1 5 1 4 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43264.1 - 2.8e-25 85.8 1.9 8e-06 25.6 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ribosomal_S5_C PF03719.10 KEZ43264.1 - 0.12 11.6 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain XRCC1_N PF01834.11 KEZ43264.1 - 0.16 11.3 0.1 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 XRCC1 N terminal domain CDC37_M PF08565.6 KEZ43265.1 - 5.3e-28 97.6 0.1 1.1e-27 96.5 0.1 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KEZ43265.1 - 3.6e-19 68.4 0.4 3.6e-19 68.4 0.2 2.3 3 0 0 3 3 3 1 Cdc37 C terminal domain CDC37_N PF03234.9 KEZ43265.1 - 1.2e-16 61.5 0.1 3.8e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding CPT PF07931.7 KEZ43265.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MFS_1 PF07690.11 KEZ43266.1 - 2e-16 59.6 50.8 2e-16 59.6 35.2 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43266.1 - 0.0015 17.1 9.4 0.0015 17.1 6.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Copper-bind PF00127.15 KEZ43267.1 - 0.03 14.5 0.1 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Borrelia_P83 PF05262.6 KEZ43268.1 - 8.1 4.5 24.2 12 4.0 16.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_hydro_7 PF00840.15 KEZ43269.1 - 4.3e-183 608.5 6.7 5e-183 608.3 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CFEM PF05730.6 KEZ43270.1 - 4.2e-08 32.8 9.0 6e-08 32.3 6.2 1.2 1 0 0 1 1 1 1 CFEM domain zf-Paramyx-P PF13008.2 KEZ43270.1 - 0.013 14.6 4.0 0.029 13.5 2.8 1.5 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein Lipase_GDSL_2 PF13472.1 KEZ43272.1 - 1.4e-12 48.1 0.0 1.7e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ43272.1 - 4.2e-09 36.5 0.0 7.3e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KEZ43272.1 - 0.0027 17.4 0.0 0.0087 15.8 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FhuF_C PF11575.3 KEZ43274.1 - 3.7 7.2 9.4 1.5 8.5 0.3 3.1 2 1 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain MFS_1 PF07690.11 KEZ43275.1 - 5.6e-30 104.2 24.6 9.3e-30 103.5 17.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PIRT PF15099.1 KEZ43275.1 - 0.075 12.2 0.1 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF1065 PF06358.6 KEZ43275.1 - 0.26 11.0 3.3 0.18 11.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) MitoNEET_N PF10660.4 KEZ43275.1 - 1.1 9.1 3.8 0.41 10.5 0.3 2.1 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus MFS_1 PF07690.11 KEZ43276.1 - 2.1e-22 79.3 27.2 4.5e-14 51.9 6.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily CcmD PF04995.9 KEZ43276.1 - 0.19 11.5 2.7 0.33 10.7 0.5 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Aldolase_II PF00596.16 KEZ43277.1 - 5.9e-42 143.3 0.1 7.4e-42 143.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ank_2 PF12796.2 KEZ43278.1 - 4.3e-52 174.4 0.0 8.2e-14 51.7 0.1 6.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ43278.1 - 2e-46 155.5 0.3 9.5e-07 29.1 0.1 9.4 3 1 7 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.25 KEZ43278.1 - 5.6e-41 136.3 9.4 0.00054 19.6 0.0 12.7 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.1 KEZ43278.1 - 6.4e-39 131.1 3.8 5.1e-08 32.9 0.1 8.9 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43278.1 - 4.8e-34 112.9 5.9 0.0044 17.1 0.0 12.6 13 0 0 13 13 13 7 Ankyrin repeat A_thal_3526 PF09713.5 KEZ43278.1 - 0.053 13.6 0.0 2.2 8.4 0.0 3.1 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) DUF1296 PF06972.6 KEZ43278.1 - 0.18 11.8 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) DUF771 PF05595.6 KEZ43278.1 - 0.19 11.6 0.0 0.61 10.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF771) HSP70 PF00012.15 KEZ43279.1 - 1.3e-05 23.3 0.2 0.00017 19.6 0.0 2.4 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ43279.1 - 0.13 10.8 0.0 6.9 5.1 0.0 3.1 4 0 0 4 4 4 0 MreB/Mbl protein FliJ PF02050.11 KEZ43280.1 - 0.0028 17.7 2.7 0.058 13.4 0.3 2.5 2 0 0 2 2 2 2 Flagellar FliJ protein Aldo_ket_red PF00248.16 KEZ43281.1 - 1.6e-65 220.7 0.0 2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 KEZ43282.1 - 3.1e-22 78.7 9.8 3.1e-22 78.7 6.8 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 KEZ43284.1 - 2.3e-25 89.1 0.0 3.4e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Rrf2 PF02082.15 KEZ43284.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 KEZ43284.1 - 0.035 13.7 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.15 KEZ43284.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family FAD_binding_4 PF01565.18 KEZ43286.1 - 9.2e-22 77.0 0.2 5.7e-21 74.4 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain PDEase_II PF02112.10 KEZ43286.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II AA_permease_2 PF13520.1 KEZ43287.1 - 3.7e-83 279.4 29.7 4.4e-83 279.1 20.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ43287.1 - 5.6e-16 57.9 28.1 1.1e-15 56.9 19.5 1.7 1 1 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 KEZ43289.1 - 0.0002 20.3 0.1 0.00035 19.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PMBR PF09373.5 KEZ43289.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Pseudomurein-binding repeat Mito_carr PF00153.22 KEZ43290.1 - 2.4e-41 139.3 0.5 8.1e-20 70.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KEZ43290.1 - 1.7e-11 44.0 0.4 3.2e-08 33.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KEZ43290.1 - 1.4e-10 39.6 0.0 1.7e-06 26.9 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 KEZ43290.1 - 4.3e-10 38.5 0.0 0.0075 16.0 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KEZ43290.1 - 9.4e-08 31.5 0.1 1.3e-05 24.7 0.1 2.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KEZ43290.1 - 2.3e-07 29.8 1.6 6.9e-06 25.1 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.2 KEZ43290.1 - 0.034 13.8 0.1 11 5.7 0.0 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand HET PF06985.6 KEZ43291.1 - 1.8e-37 128.5 0.0 3.1e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEZ43292.1 - 1.5e-13 50.1 47.5 2e-07 30.0 14.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ43292.1 - 1.2e-06 27.0 14.4 1.2e-06 27.0 10.0 2.1 1 1 2 3 3 3 1 Fungal trichothecene efflux pump (TRI12) NACHT PF05729.7 KEZ43293.1 - 3.2e-07 30.1 0.3 2.2e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ43293.1 - 0.00033 20.8 0.5 0.026 14.6 0.0 3.2 3 1 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 KEZ43293.1 - 0.1 11.5 0.0 0.26 10.2 0.0 1.6 1 0 0 1 1 1 0 KAP family P-loop domain P5CR_dimer PF14748.1 KEZ43294.1 - 4.4e-37 126.3 2.0 5.8e-37 125.9 0.2 2.1 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KEZ43294.1 - 2e-16 60.1 0.4 6.8e-16 58.4 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KEZ43294.1 - 0.0023 17.7 1.7 0.036 13.7 1.2 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KEZ43294.1 - 0.018 15.1 0.1 0.046 13.8 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 KEZ43294.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 KEZ43294.1 - 0.092 13.0 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding MnhB PF04039.8 KEZ43295.1 - 0.23 11.5 5.1 0.14 12.2 1.9 1.9 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Lipase_GDSL_2 PF13472.1 KEZ43296.1 - 1e-13 51.7 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3348 PF11828.3 KEZ43296.1 - 0.27 10.6 0.0 2 7.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) Lipase_GDSL PF00657.17 KEZ43296.1 - 0.54 10.0 3.3 1.6 8.5 2.1 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Clr5 PF14420.1 KEZ43297.1 - 3.8e-06 26.7 0.9 6.3e-06 25.9 0.6 1.4 1 0 0 1 1 1 1 Clr5 domain AAA PF00004.24 KEZ43298.1 - 0.034 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ43298.1 - 0.12 12.3 0.1 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RskA PF10099.4 KEZ43301.1 - 0.045 13.4 1.0 0.052 13.2 0.1 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Cu_amine_oxid PF01179.15 KEZ43302.1 - 2.6e-107 359.0 1.4 1.8e-86 290.4 0.7 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KEZ43302.1 - 5.9e-09 35.8 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain SBP_bac_10 PF07596.6 KEZ43302.1 - 0.064 13.2 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) Orthopox_F7 PF05813.7 KEZ43303.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus F7 protein Pkinase PF00069.20 KEZ43305.1 - 1.1e-06 27.9 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KEZ43305.1 - 0.00015 21.5 1.0 0.00032 20.4 0.7 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEZ43305.1 - 0.0021 17.1 0.0 0.0096 15.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family LrgB PF04172.11 KEZ43306.1 - 2.9e-19 69.0 18.1 7.3e-19 67.7 9.4 3.0 2 1 0 2 2 2 1 LrgB-like family DUF2215 PF10225.4 KEZ43306.1 - 0.53 9.6 4.1 0.66 9.3 1.9 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) FAD_binding_3 PF01494.14 KEZ43308.1 - 6.8e-19 68.1 0.1 2.1e-18 66.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ43308.1 - 1.5e-11 43.8 1.2 2.1e-09 36.7 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ43308.1 - 5.6e-08 32.6 0.2 1.4e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ43308.1 - 6.9e-07 28.4 1.1 1.1e-06 27.8 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ43308.1 - 8.6e-07 29.0 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ43308.1 - 3.3e-05 24.1 0.5 0.0001 22.5 0.4 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ43308.1 - 0.00014 21.0 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 KEZ43308.1 - 0.00031 20.3 0.1 0.00073 19.1 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADC PF06314.6 KEZ43308.1 - 0.00049 19.5 0.0 0.00093 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) HI0933_like PF03486.9 KEZ43308.1 - 0.00075 18.0 0.3 0.0011 17.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 KEZ43308.1 - 0.0024 16.8 0.3 0.03 13.2 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KEZ43308.1 - 0.0026 17.8 0.1 0.0062 16.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEZ43308.1 - 0.0034 16.0 0.3 0.0048 15.5 0.2 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 KEZ43308.1 - 0.0095 14.8 0.3 0.013 14.3 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KEZ43308.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 KEZ43308.1 - 0.035 13.5 0.2 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Strep_67kDa_ant PF06100.6 KEZ43308.1 - 0.046 12.0 0.1 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family TrkA_N PF02254.13 KEZ43308.1 - 0.067 13.1 0.2 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KEZ43308.1 - 0.09 12.4 0.1 0.19 11.3 0.0 1.5 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VPEP PF07589.6 KEZ43308.1 - 0.12 12.2 0.6 0.28 11.1 0.4 1.6 1 0 0 1 1 1 0 PEP-CTERM motif Fungal_trans PF04082.13 KEZ43309.1 - 0.00042 19.2 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Josephin PF02099.12 KEZ43309.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Josephin gag-asp_proteas PF13975.1 KEZ43310.1 - 5.5e-07 29.3 0.0 9.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KEZ43310.1 - 1.1e-06 29.0 0.0 7.7e-05 23.1 0.0 2.3 1 1 1 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KEZ43310.1 - 0.0026 17.3 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 2 Aspartyl protease 4HBT_3 PF13622.1 KEZ43311.1 - 1e-41 143.3 0.0 1.2e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.20 KEZ43312.1 - 6.5e-32 110.6 0.0 1.4e-31 109.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43312.1 - 2.2e-11 43.3 0.0 3.5e-06 26.2 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KEZ43312.1 - 0.04 12.8 0.3 0.9 8.4 0.0 2.1 2 0 0 2 2 2 0 Kinase-like MFS_1 PF07690.11 KEZ43313.1 - 1.3e-33 116.1 39.3 2.1e-33 115.5 27.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldedh PF00171.17 KEZ43314.1 - 3.6e-15 55.2 0.0 6.5e-14 51.1 0.0 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF815 PF05673.8 KEZ43314.1 - 0.034 13.0 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sec3_C PF09763.4 KEZ43314.1 - 0.21 9.6 0.0 0.4 8.7 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF1502 PF07397.6 KEZ43315.1 - 4.7 6.9 6.9 0.29 10.7 0.9 1.9 2 0 0 2 2 2 0 Repeat of unknown function (DUF1502) FAA_hydrolase PF01557.13 KEZ43316.1 - 8e-50 169.2 0.0 1.1e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KEZ43316.1 - 7.7e-14 51.5 0.0 8.2e-13 48.2 0.0 2.2 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal ADC PF06314.6 KEZ43317.1 - 1.3e-12 47.6 0.0 5.1e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.14 KEZ43317.1 - 4.2e-12 45.7 0.0 6.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_S15 PF02129.13 KEZ43318.1 - 1.7e-41 142.4 0.4 2.5e-41 141.9 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KEZ43318.1 - 1.4e-38 132.9 0.1 2.1e-38 132.3 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KEZ43318.1 - 2.5e-05 24.2 0.2 5.3e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ43318.1 - 0.0003 20.5 0.1 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEZ43318.1 - 0.03 14.1 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase LigB PF02900.13 KEZ43319.1 - 3e-26 92.0 0.1 5.5e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase NACHT PF05729.7 KEZ43319.1 - 6e-11 42.2 0.0 1.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_12 PF13424.1 KEZ43319.1 - 2e-07 30.8 9.8 0.23 11.4 0.2 6.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ43319.1 - 0.00051 19.6 9.3 1.1 9.1 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.1 KEZ43319.1 - 0.0008 19.4 0.0 0.0008 19.4 0.0 2.9 4 0 0 4 4 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ43319.1 - 0.0028 17.8 0.0 0.012 15.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 KEZ43319.1 - 0.013 16.0 40.0 0.77 10.5 0.0 10.4 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ43319.1 - 0.021 14.4 0.1 0.021 14.4 0.1 7.5 6 1 4 10 10 9 0 TPR repeat AAA_17 PF13207.1 KEZ43319.1 - 0.043 14.6 0.0 0.3 11.9 0.0 2.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KEZ43319.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TPR_10 PF13374.1 KEZ43319.1 - 0.081 12.8 6.7 0.65 10.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ43319.1 - 0.11 12.1 0.0 0.11 12.1 0.0 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat AAA_18 PF13238.1 KEZ43319.1 - 0.12 12.7 0.0 0.53 10.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 KEZ43319.1 - 0.14 12.2 0.0 0.48 10.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.16 KEZ43319.1 - 0.15 11.2 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TPR_8 PF13181.1 KEZ43319.1 - 0.19 11.6 3.2 6.7 6.7 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ43319.1 - 0.54 10.8 11.9 12 6.5 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ43319.1 - 6 7.3 9.3 18 5.8 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Methyltransf_2 PF00891.13 KEZ43321.1 - 8.3e-30 103.7 0.0 1.3e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEZ43321.1 - 0.00018 22.0 0.0 0.00041 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KEZ43321.1 - 0.038 14.8 0.0 0.26 12.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF1664 PF07889.7 KEZ43322.1 - 0.08 12.7 5.0 0.88 9.3 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Methyltransf_23 PF13489.1 KEZ43323.1 - 7.4e-23 81.0 0.0 1.5e-22 80.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ43323.1 - 1.3e-11 45.0 0.0 4.5e-10 40.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43323.1 - 7.7e-09 35.3 0.0 4e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43323.1 - 1.5e-08 34.9 0.0 2.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ43323.1 - 1.4e-07 31.8 0.0 1e-06 29.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ43323.1 - 7e-06 26.3 0.0 2e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ43323.1 - 7e-05 22.8 0.1 0.00085 19.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ43323.1 - 0.00062 19.8 0.0 0.0016 18.4 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 KEZ43323.1 - 0.0025 17.1 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KEZ43323.1 - 0.03 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 KEZ43323.1 - 0.069 12.5 0.0 0.96 8.8 0.0 2.5 2 1 1 3 3 3 0 Putative methyltransferase GidB PF02527.10 KEZ43323.1 - 0.19 10.8 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cation_efflux PF01545.16 KEZ43324.1 - 2.7e-27 95.5 3.8 3.7e-27 95.1 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family 4HBT_2 PF13279.1 KEZ43325.1 - 4.6e-18 65.8 0.3 8e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Endonuc_subdom PF09062.5 KEZ43325.1 - 0.1 13.3 0.2 0.29 11.9 0.1 1.8 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain Lactonase PF10282.4 KEZ43326.1 - 2.9e-26 92.3 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.7 KEZ43326.1 - 0.025 14.2 1.8 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RTA1 PF04479.8 KEZ43328.1 - 1.6e-52 178.2 7.3 2.4e-52 177.6 5.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF485 PF04341.7 KEZ43328.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF485 ubiquitin PF00240.18 KEZ43329.1 - 0.0046 16.3 0.4 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family p450 PF00067.17 KEZ43330.1 - 3.9e-69 233.3 0.0 4.5e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LEAP-2 PF07359.6 KEZ43331.1 - 0.066 12.8 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) PulG PF11773.3 KEZ43331.1 - 0.38 10.5 1.8 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin GMC_oxred_N PF00732.14 KEZ43332.1 - 5.4e-47 160.3 0.0 7.1e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ43332.1 - 2.5e-33 115.3 0.0 4.9e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ43332.1 - 8.5e-06 24.8 0.0 0.025 13.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ43332.1 - 0.00071 18.5 0.1 0.0052 15.7 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ43332.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ43332.1 - 0.022 14.7 0.1 0.16 12.0 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEZ43332.1 - 0.028 13.0 0.2 0.04 12.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KEZ43332.1 - 0.053 11.9 0.0 0.082 11.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ43332.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ArsB PF02040.10 KEZ43333.1 - 1.1e-20 74.0 15.0 4.5e-15 55.5 3.1 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF3708 PF12501.3 KEZ43333.1 - 0.016 15.0 1.2 0.3 10.9 0.0 2.8 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter zf-C2H2_4 PF13894.1 KEZ43334.1 - 0.0016 18.6 7.1 2.6 8.5 0.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger Sgf11 PF08209.6 KEZ43334.1 - 3 7.2 8.4 5.6 6.3 0.3 3.1 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Cyclin_C PF02984.14 KEZ43335.1 - 0.09 12.7 0.3 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Cyclin, C-terminal domain 4HBT_2 PF13279.1 KEZ43336.1 - 1.6e-05 25.3 0.0 2.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily COesterase PF00135.23 KEZ43337.1 - 3.5e-78 263.6 0.0 4.4e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ43337.1 - 0.00021 20.9 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ43337.1 - 0.092 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Phage_GPO PF05929.6 KEZ43337.1 - 0.18 11.0 0.1 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HET PF06985.6 KEZ43338.1 - 9.9e-27 93.7 0.0 1.6e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMN_dh PF01070.13 KEZ43339.1 - 1.3e-41 142.6 0.0 1.8e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEZ43339.1 - 6.1e-24 83.6 0.0 1.3e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribonuc_L-PSP PF01042.16 KEZ43340.1 - 1.4e-28 99.0 0.0 1.7e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aminotran_1_2 PF00155.16 KEZ43341.1 - 2.5e-34 118.7 0.0 3.2e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ43341.1 - 0.061 12.4 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.16 KEZ43341.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Peptidase_S10 PF00450.17 KEZ43342.1 - 7.1e-71 239.5 0.0 2e-70 238.0 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KEZ43342.1 - 0.0052 16.6 0.2 0.04 13.8 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 KEZ43343.1 - 9.2e-74 249.0 0.0 1.1e-73 248.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KEZ43343.1 - 5.6e-08 32.9 0.6 1.4e-06 28.3 0.4 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ43343.1 - 0.00027 20.7 0.0 0.00096 18.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 KEZ43344.1 - 1.6e-09 37.5 8.4 2.7e-09 36.7 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.10 KEZ43345.1 - 5.8e-148 494.0 56.3 6.7e-148 493.8 39.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S10 PF00450.17 KEZ43345.1 - 0.063 12.4 0.1 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase DUF2937 PF11157.3 KEZ43345.1 - 4.6 6.5 8.6 0.98 8.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) Pro_racemase PF05544.6 KEZ43346.1 - 1.5e-61 208.0 0.0 1.9e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.11 KEZ43346.1 - 0.045 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein MFS_1 PF07690.11 KEZ43347.1 - 1.7e-16 59.8 20.4 1.7e-16 59.8 14.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily LrgA PF03788.9 KEZ43347.1 - 0.085 12.5 0.1 0.085 12.5 0.1 2.9 3 0 0 3 3 3 0 LrgA family ABC_tran PF00005.22 KEZ43348.1 - 5.3e-42 143.3 0.1 8.9e-25 87.5 0.0 3.3 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ43348.1 - 3.4e-25 88.9 37.2 5e-14 52.3 6.8 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 KEZ43348.1 - 2e-15 57.5 0.0 0.0013 18.7 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 KEZ43348.1 - 4.9e-07 29.2 0.0 0.21 10.7 0.5 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEZ43348.1 - 5.9e-07 28.9 0.9 0.013 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KEZ43348.1 - 3e-06 26.7 0.3 0.055 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KEZ43348.1 - 4.7e-06 27.0 0.8 0.0085 16.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ43348.1 - 8.9e-06 25.8 0.5 0.0066 16.4 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 KEZ43348.1 - 1.4e-05 24.9 0.3 0.12 12.2 0.2 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ43348.1 - 4.2e-05 22.7 0.1 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KEZ43348.1 - 6.6e-05 23.3 0.1 0.016 15.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 KEZ43348.1 - 0.00015 21.9 1.2 0.46 10.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ43348.1 - 0.00021 22.0 0.9 0.068 13.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 KEZ43348.1 - 0.00032 19.6 0.3 0.1 11.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 KEZ43348.1 - 0.00099 18.8 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KEZ43348.1 - 0.0011 18.0 0.9 0.8 8.7 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 KEZ43348.1 - 0.0013 18.2 2.0 1.3 8.3 0.0 3.4 3 1 0 3 3 3 2 AAA-like domain AAA_30 PF13604.1 KEZ43348.1 - 0.0056 16.2 0.6 1.5 8.3 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEZ43348.1 - 0.0071 16.2 0.1 0.17 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KEZ43348.1 - 0.01 15.6 0.3 0.74 9.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DUP PF00674.13 KEZ43348.1 - 0.014 15.3 0.4 0.052 13.5 0.3 2.0 1 0 0 1 1 1 0 DUP family AAA_18 PF13238.1 KEZ43348.1 - 0.017 15.3 0.2 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KEZ43348.1 - 0.034 12.9 2.0 2.5 6.7 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_14 PF13173.1 KEZ43348.1 - 0.056 13.3 0.1 0.47 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ43348.1 - 0.061 13.5 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KEZ43348.1 - 0.063 12.9 0.1 4.7 6.8 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KEZ43348.1 - 0.14 11.6 0.2 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KEZ43348.1 - 0.14 12.1 1.8 1.6 8.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 KEZ43348.1 - 0.15 11.6 1.4 2.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 KEZ43348.1 - 1.2 8.8 3.7 5.8 6.6 0.0 2.7 3 0 0 3 3 3 0 NTPase Amidohydro_4 PF13147.1 KEZ43349.1 - 1.3e-10 41.7 6.0 1.3e-07 31.9 0.2 3.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KEZ43349.1 - 4.3e-08 33.2 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KEZ43349.1 - 0.00015 21.1 0.1 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family SCP1201-deam PF14428.1 KEZ43349.1 - 0.00091 18.9 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 SCP1.201-like deaminase Peptidase_S10 PF00450.17 KEZ43350.1 - 3.1e-76 257.2 0.0 1.8e-59 201.9 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase Glyco_hydro_3 PF00933.16 KEZ43352.1 - 4.4e-83 278.7 0.1 6e-83 278.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ43352.1 - 5.3e-46 156.9 0.2 4.4e-45 153.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ43352.1 - 2.9e-19 68.7 0.0 6.1e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Zn_clus PF00172.13 KEZ43353.1 - 6e-09 35.6 6.3 1.1e-08 34.7 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ43353.1 - 1.1e-08 34.2 0.0 2.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAM217 PF15344.1 KEZ43353.1 - 0.24 10.9 2.7 2.2 7.7 0.0 2.6 3 0 0 3 3 3 0 FAM217 family Sulfatase PF00884.18 KEZ43354.1 - 5e-75 252.5 0.0 6e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 KEZ43354.1 - 2.8e-05 24.4 0.1 0.0013 19.0 0.1 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KEZ43354.1 - 0.0036 16.6 0.1 0.28 10.4 0.0 2.3 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KEZ43354.1 - 0.0077 14.6 0.0 0.017 13.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sugar_tr PF00083.19 KEZ43355.1 - 6.9e-80 268.8 21.2 7.8e-80 268.6 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43355.1 - 1.1e-15 57.2 19.8 1.1e-15 57.2 13.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KEZ43355.1 - 0.017 15.1 1.6 0.045 13.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Cupin_2 PF07883.6 KEZ43356.1 - 9.8e-21 73.0 1.1 5.3e-19 67.4 0.2 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KEZ43356.1 - 1.2e-06 28.0 0.0 0.0083 15.5 0.0 2.3 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 KEZ43356.1 - 3.1e-05 23.6 0.1 5.5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 KEZ43356.1 - 0.002 17.4 0.3 0.044 13.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF861) ARD PF03079.9 KEZ43356.1 - 0.1 12.5 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family Cupin_6 PF12852.2 KEZ43356.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Cupin Fungal_trans PF04082.13 KEZ43357.1 - 1.3e-23 83.2 0.2 2e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_3 PF01764.20 KEZ43358.1 - 4.7e-23 81.3 0.0 8.1e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Anemone_cytotox PF06369.7 KEZ43359.1 - 0.00028 20.3 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Sea anemone cytotoxic protein Kinesin PF00225.18 KEZ43360.1 - 2.3e-59 200.8 0.0 2.9e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain MFS_1 PF07690.11 KEZ43361.1 - 1e-34 119.7 38.6 1.4e-34 119.3 24.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ43361.1 - 0.0024 17.6 1.1 0.0024 17.6 0.8 2.3 2 0 0 2 2 2 1 MFS_1 like family Syndecan PF01034.15 KEZ43361.1 - 0.02 14.5 0.0 0.066 12.8 0.0 1.9 1 0 0 1 1 1 0 Syndecan domain p450 PF00067.17 KEZ43362.1 - 2e-30 105.7 0.0 2.6e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEZ43363.1 - 3.7e-42 144.3 49.0 5.3e-42 143.7 33.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ43363.1 - 1.5e-16 59.7 16.2 1.5e-16 59.7 11.2 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEZ43363.1 - 3.9e-12 45.5 11.9 3.9e-12 45.5 8.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Pox_I5 PF04713.7 KEZ43363.1 - 0.48 10.1 4.3 0.65 9.7 1.4 2.3 2 0 0 2 2 2 0 Poxvirus protein I5 adh_short PF00106.20 KEZ43364.1 - 7.7e-17 61.7 0.6 1.5e-15 57.4 0.1 2.1 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ43364.1 - 2.3e-07 30.6 0.2 4.7e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEZ43364.1 - 3.9e-07 30.0 0.0 7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ43364.1 - 6.9e-05 22.9 0.5 0.00022 21.2 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEZ43364.1 - 0.00093 18.6 0.1 0.0021 17.5 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEZ43364.1 - 0.035 13.8 0.2 0.093 12.5 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KEZ43364.1 - 0.066 12.0 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 KEZ43364.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KEZ43364.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 KEZ43364.1 - 0.15 11.1 0.2 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.20 KEZ43365.1 - 6.6e-15 55.4 0.0 8.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ43365.1 - 1.8e-06 27.7 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ43365.1 - 7.5e-06 25.8 0.0 9.7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KEZ43366.1 - 3e-78 262.8 0.0 7.4e-78 261.5 0.0 1.7 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 KEZ43366.1 - 4.8e-78 262.4 0.0 1.1e-77 261.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme PS-DH PF14765.1 KEZ43366.1 - 3.5e-51 174.1 0.0 7.3e-51 173.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEZ43366.1 - 8.7e-51 173.1 0.0 1.5e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEZ43366.1 - 1.1e-47 162.0 0.1 3.4e-47 160.4 0.0 1.9 2 0 0 2 2 1 1 KR domain Condensation PF00668.15 KEZ43366.1 - 1.5e-45 155.3 0.0 2.3e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KEZ43366.1 - 2.4e-41 141.4 0.3 7.7e-39 133.2 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KEZ43366.1 - 2.2e-38 131.5 0.0 2.2e-37 128.3 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KEZ43366.1 - 6.7e-29 100.1 0.0 1.5e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEZ43366.1 - 3.7e-19 69.0 0.0 9.6e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEZ43366.1 - 3.3e-15 56.1 3.2 4.3e-08 33.3 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KEZ43366.1 - 1.3e-14 54.0 0.0 4.1e-14 52.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 KEZ43366.1 - 9.9e-13 48.0 0.0 9.5e-11 41.5 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 KEZ43366.1 - 1.6e-12 47.7 0.0 4.5e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ43366.1 - 5.9e-12 45.6 0.0 1.8e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KEZ43366.1 - 1.4e-10 41.3 0.1 5.2e-10 39.5 0.0 2.1 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 KEZ43366.1 - 6.8e-09 36.2 0.0 8.5e-08 32.7 0.0 3.1 3 0 0 3 3 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ43366.1 - 6.5e-07 28.7 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEZ43366.1 - 1.2e-06 28.1 0.0 8.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ43366.1 - 1.3e-05 25.5 0.0 3.6e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KEZ43366.1 - 0.00049 18.9 0.0 0.0021 16.8 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 KEZ43366.1 - 0.00076 18.5 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NodS PF05401.6 KEZ43366.1 - 0.001 18.5 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 KEZ43366.1 - 0.0021 18.0 0.0 0.0071 16.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Toprim PF01751.17 KEZ43366.1 - 0.04 13.8 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Toprim domain RrnaAD PF00398.15 KEZ43366.1 - 0.047 12.7 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ACP_syn_III PF08545.5 KEZ43366.1 - 0.13 11.9 1.7 0.48 10.1 0.4 2.6 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.21 KEZ43368.1 - 0.00061 19.3 0.3 0.0033 16.9 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ43368.1 - 0.0022 17.7 0.0 0.0077 15.9 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KEZ43369.1 - 2.4e-13 49.4 0.0 3.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 KEZ43370.1 - 2.3e-05 24.1 0.0 7e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KEZ43371.1 - 1.6e-67 228.0 0.0 2.1e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 KEZ43371.1 - 1.1e-48 165.4 0.0 1.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_10 PF13460.1 KEZ43372.1 - 4.8e-13 49.5 0.3 6.5e-13 49.0 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ43372.1 - 8.1e-12 44.4 0.5 1.4e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ43372.1 - 1.4e-11 44.3 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEZ43372.1 - 1.5e-11 44.0 0.4 2.1e-11 43.5 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KEZ43372.1 - 2.3e-08 33.2 0.1 7.9e-07 28.2 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KEZ43372.1 - 0.00011 22.1 0.4 0.00021 21.2 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KEZ43372.1 - 0.012 14.5 0.1 0.022 13.6 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.18 KEZ43373.1 - 2.5e-19 69.1 0.5 3.2e-14 52.6 0.0 2.4 1 1 1 2 2 2 2 FAD binding domain BBE PF08031.7 KEZ43373.1 - 2.9e-06 27.0 0.3 7.7e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.17 KEZ43374.1 - 2.1e-34 118.8 0.0 2.7e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KEZ43375.1 - 1.2e-66 224.8 0.1 2.3e-66 223.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KEZ43375.1 - 2.2e-35 121.0 0.2 4.4e-35 120.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KEZ43375.1 - 4.6e-34 118.1 0.0 1.2e-29 103.7 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 KEZ43375.1 - 1.9e-22 79.8 0.0 4.9e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KEZ43375.1 - 1.3e-18 66.9 3.8 2.1e-08 34.3 0.9 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KEZ43375.1 - 7.6e-14 51.9 0.0 1.8e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43375.1 - 1.2e-08 34.7 0.0 2.8e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ43375.1 - 5.3e-08 32.7 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 KEZ43375.1 - 3e-07 29.8 0.0 3.9e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_18 PF12847.2 KEZ43375.1 - 3.1e-07 30.9 0.0 1.2e-06 29.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43375.1 - 3.8e-06 27.2 0.0 9.6e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ43375.1 - 2.9e-05 23.2 0.0 8e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ43375.1 - 5.8e-05 23.3 0.0 0.0002 21.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 KEZ43375.1 - 8.3e-05 22.3 0.0 0.036 13.8 0.0 3.0 3 0 0 3 3 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 KEZ43375.1 - 0.0002 20.4 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.2 KEZ43375.1 - 0.0017 18.2 0.2 0.037 13.8 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_16 PF10294.4 KEZ43375.1 - 0.0046 16.4 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_28 PF02636.12 KEZ43375.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 KEZ43375.1 - 0.18 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 KEZ43375.1 - 0.29 10.1 0.0 0.52 9.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Vps16_C PF04840.7 KEZ43375.1 - 0.31 9.9 0.1 0.52 9.2 0.1 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region ABC2_membrane PF01061.19 KEZ43377.1 - 9.3e-84 279.7 53.5 1.9e-44 151.3 19.1 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEZ43377.1 - 6.4e-41 139.8 0.1 2.9e-21 76.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEZ43377.1 - 5.9e-22 77.2 0.0 1.6e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 CDR ABC transporter AAA_25 PF13481.1 KEZ43377.1 - 8e-07 28.6 0.7 0.016 14.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEZ43377.1 - 4.3e-06 26.0 0.1 0.0004 19.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEZ43377.1 - 8e-06 26.1 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KEZ43377.1 - 3.1e-05 24.1 0.0 0.088 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ43377.1 - 3.4e-05 23.9 1.3 0.29 11.1 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KEZ43377.1 - 0.00012 22.2 0.2 0.45 10.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KEZ43377.1 - 0.00025 21.0 0.0 0.00082 19.4 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KEZ43377.1 - 0.00029 20.7 0.1 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEZ43377.1 - 0.00029 20.8 0.2 0.0085 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 KEZ43377.1 - 0.00035 20.0 0.3 0.29 10.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ43377.1 - 0.00041 21.1 0.0 0.051 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KEZ43377.1 - 0.00047 20.0 0.0 0.25 11.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KEZ43377.1 - 0.00072 19.3 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase cobW PF02492.14 KEZ43377.1 - 0.0011 18.4 0.7 0.17 11.3 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KEZ43377.1 - 0.0019 17.7 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family UPF0079 PF02367.12 KEZ43377.1 - 0.012 15.1 0.3 0.3 10.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 KEZ43377.1 - 0.016 14.7 0.3 0.25 10.8 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KEZ43377.1 - 0.019 14.5 0.2 1.6 8.3 0.2 2.4 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.1 KEZ43377.1 - 0.027 14.3 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 KEZ43377.1 - 0.034 13.8 0.1 10 5.9 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain ABC2_membrane_3 PF12698.2 KEZ43377.1 - 0.045 12.7 40.8 0.22 10.5 8.6 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein NTPase_1 PF03266.10 KEZ43377.1 - 0.045 13.4 0.2 6.7 6.4 0.1 3.3 3 1 0 3 3 3 0 NTPase Thymidylate_kin PF02223.12 KEZ43377.1 - 0.046 13.0 0.0 4.2 6.6 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Miro PF08477.8 KEZ43377.1 - 0.046 14.2 0.1 3 8.3 0.0 2.9 2 1 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KEZ43377.1 - 0.053 12.9 0.2 9.2 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 KEZ43377.1 - 0.064 12.0 0.3 1.2 7.8 0.1 2.4 2 0 0 2 2 2 0 ArgK protein T2SE PF00437.15 KEZ43377.1 - 0.075 11.9 0.2 4.2 6.1 0.1 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_15 PF13175.1 KEZ43377.1 - 0.094 11.7 0.0 3.5 6.5 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 KEZ43377.1 - 0.22 11.1 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.1 KEZ43377.1 - 0.28 10.7 0.2 3.5 7.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KEZ43377.1 - 0.3 10.0 0.0 2.1 7.2 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_30 PF13604.1 KEZ43377.1 - 0.36 10.3 1.7 5.5 6.5 0.3 2.8 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.5 KEZ43377.1 - 0.39 9.9 0.2 3.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_13 PF13166.1 KEZ43377.1 - 2.1 6.7 0.9 5.2 5.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NMT1 PF09084.6 KEZ43378.1 - 6.1e-77 258.0 0.0 8.1e-77 257.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 KEZ43378.1 - 1.5e-07 31.1 0.5 0.078 12.3 0.0 3.6 2 1 2 4 4 4 3 NMT1-like family Phosphonate-bd PF12974.2 KEZ43378.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.2 KEZ43378.1 - 0.03 13.2 0.0 0.1 11.5 0.0 1.7 2 0 0 2 2 2 0 PBP superfamily domain Beta-lactamase PF00144.19 KEZ43379.1 - 2.9e-31 108.7 0.1 5.1e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase Cyclase PF04199.8 KEZ43379.1 - 5.2e-16 58.8 0.0 9.2e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase SGL PF08450.7 KEZ43380.1 - 4.5e-13 49.1 0.7 6.5e-13 48.6 0.5 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KEZ43380.1 - 1.4e-05 24.7 0.4 0.051 13.5 0.0 4.0 3 0 0 3 3 3 2 NHL repeat Aldo_ket_red PF00248.16 KEZ43381.1 - 3.1e-22 78.7 0.0 3.6e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Transketolase_N PF00456.16 KEZ43382.1 - 6e-121 403.3 0.1 5.8e-120 400.0 0.0 2.1 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KEZ43382.1 - 5.3e-39 133.5 0.0 1.2e-38 132.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KEZ43382.1 - 8.8e-08 31.2 0.7 1.4e-07 30.5 0.5 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 KEZ43382.1 - 5.4e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KEZ43382.1 - 8.3e-07 28.1 0.0 4.7e-06 25.7 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KEZ43382.1 - 0.00054 19.5 2.8 0.016 14.7 1.5 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain F_bP_aldolase PF01116.15 KEZ43383.1 - 7.7e-74 248.3 0.0 8.6e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MFS_1 PF07690.11 KEZ43384.1 - 8e-18 64.2 32.9 8e-18 64.2 22.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEZ43384.1 - 1.1e-10 41.2 11.7 1.1e-10 41.2 6.3 2.3 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 RasGEF PF00617.14 KEZ43385.1 - 3.2e-55 186.7 0.0 5.6e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KEZ43385.1 - 5e-19 68.3 0.0 1.7e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KEZ43385.1 - 5.9e-06 25.7 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ43385.1 - 9.8e-05 21.6 0.0 0.0002 20.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF4653 PF15546.1 KEZ43385.1 - 0.93 8.7 7.0 0.75 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) DUF1992 PF09350.5 KEZ43386.1 - 5.2e-23 80.6 0.8 1.2e-22 79.5 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) SET PF00856.23 KEZ43387.1 - 0.061 13.6 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 SET domain APC10 PF03256.11 KEZ43388.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Cu2_monoox_C PF03712.10 KEZ43388.1 - 0.093 12.0 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Hydantoinase_B PF02538.9 KEZ43388.1 - 0.15 10.2 0.0 0.19 9.9 0.0 1.0 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Pkinase PF00069.20 KEZ43389.1 - 2.7e-17 62.7 0.0 1.6e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43389.1 - 0.00078 18.5 0.0 0.0051 15.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase ADH_zinc_N_2 PF13602.1 KEZ43390.1 - 9.2e-15 55.6 0.0 1.7e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEZ43390.1 - 8.7e-08 31.7 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ43390.1 - 3.2e-05 23.6 0.0 0.00078 19.1 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 KEZ43390.1 - 0.029 14.2 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ELFV_dehydrog PF00208.16 KEZ43390.1 - 0.11 12.0 0.8 0.21 11.1 0.5 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Tyrosinase PF00264.15 KEZ43391.1 - 6.4e-18 65.7 0.2 1.4e-17 64.6 0.1 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase AIRS PF00586.19 KEZ43391.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain ABC1 PF03109.11 KEZ43392.1 - 9.6e-24 83.6 0.0 7.9e-15 54.8 0.0 2.4 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.17 KEZ43392.1 - 0.0034 16.7 0.0 0.047 13.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KEZ43392.1 - 0.0041 16.8 0.1 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family CFEM PF05730.6 KEZ43393.1 - 3.5e-09 36.3 10.5 6.8e-09 35.4 7.3 1.6 1 1 0 1 1 1 1 CFEM domain DUF2237 PF09996.4 KEZ43393.1 - 0.085 12.3 0.4 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) DUF1180 PF06679.7 KEZ43393.1 - 5.5 6.8 7.2 11 5.8 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MSA-2c PF12238.3 KEZ43393.1 - 6.8 6.3 6.9 9.1 5.8 4.8 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.11 KEZ43394.1 - 4.1e-14 52.0 59.2 3.3e-13 49.1 23.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ43394.1 - 1.9e-12 46.1 19.6 2.8e-12 45.6 13.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 KEZ43394.1 - 3 7.8 8.3 0.12 12.2 0.5 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Acetyltransf_7 PF13508.1 KEZ43395.1 - 3.3e-05 23.9 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEZ43395.1 - 6.7e-05 22.8 0.2 0.00014 21.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KEZ43395.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.9 KEZ43396.1 - 7.1e-21 75.0 4.4 2.4e-09 37.3 0.0 4.4 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ43396.1 - 3.3e-14 53.0 0.4 1.3e-11 44.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ43396.1 - 4.1e-09 36.8 0.3 0.00087 19.4 0.1 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ43396.1 - 6.9e-07 28.4 1.0 0.75 8.6 0.0 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ43396.1 - 1.2e-06 27.6 0.2 0.023 13.6 0.0 3.5 3 1 1 4 4 4 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEZ43396.1 - 4e-06 26.6 0.5 0.28 10.9 0.0 4.6 5 0 0 5 5 5 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KEZ43396.1 - 2.8e-05 23.1 0.5 0.00067 18.6 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KEZ43396.1 - 3.6e-05 22.5 0.2 0.44 9.0 0.0 3.1 2 1 1 3 3 3 2 Tryptophan halogenase DUF4147 PF13660.1 KEZ43396.1 - 0.0007 18.7 0.1 0.89 8.6 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4147) HI0933_like PF03486.9 KEZ43396.1 - 0.00086 17.8 1.2 0.077 11.4 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 KEZ43396.1 - 0.0017 17.2 0.3 1.9 7.2 0.0 3.0 3 1 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 KEZ43396.1 - 0.0037 17.2 0.1 0.68 9.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 KEZ43396.1 - 0.0046 16.5 0.2 2 7.9 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KEZ43396.1 - 0.044 12.8 0.1 0.49 9.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Peptidase_S28 PF05577.7 KEZ43396.1 - 0.11 11.0 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 GIDA PF01134.17 KEZ43396.1 - 0.48 9.2 14.5 2.1 7.0 0.8 3.7 3 1 1 4 4 4 0 Glucose inhibited division protein A adh_short PF00106.20 KEZ43397.1 - 1.4e-31 109.7 4.6 1.6e-31 109.4 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43397.1 - 2.4e-17 63.4 1.0 3.3e-17 63.0 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43397.1 - 1.1e-13 51.3 3.0 1.5e-13 50.7 2.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ43397.1 - 0.0085 15.5 0.3 0.013 14.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KEZ43397.1 - 0.0085 15.8 2.7 0.015 15.0 1.7 1.6 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Alk_phosphatase PF00245.15 KEZ43397.1 - 0.13 10.9 0.7 0.17 10.5 0.5 1.1 1 0 0 1 1 1 0 Alkaline phosphatase tRNA-synt_1 PF00133.17 KEZ43398.1 - 1.2e-202 674.2 0.0 1.5e-202 673.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEZ43398.1 - 5.5e-25 87.9 0.0 1.5e-24 86.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEZ43398.1 - 7.4e-19 67.6 2.2 4.2e-08 32.2 0.3 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KEZ43398.1 - 0.038 13.1 0.0 0.21 10.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Glyco_hydro_11 PF00457.12 KEZ43399.1 - 1.6e-78 262.2 22.0 2.1e-78 261.8 15.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KEZ43399.1 - 9.8e-11 41.1 19.0 9.8e-11 41.1 13.2 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KEZ43399.1 - 0.0071 16.3 8.4 0.016 15.2 5.8 1.7 1 1 0 1 1 1 1 Toxin 7 SET PF00856.23 KEZ43400.1 - 4.6e-08 33.5 0.0 1.2e-07 32.2 0.0 1.7 1 1 0 1 1 1 1 SET domain UFD1 PF03152.9 KEZ43401.1 - 3.4e-29 101.2 0.0 5.9e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-C2H2 PF00096.21 KEZ43401.1 - 0.055 13.8 19.0 1.4 9.3 0.1 5.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type PRP21_like_P PF12230.3 KEZ43401.1 - 0.12 11.8 0.5 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-ribbon_3 PF13248.1 KEZ43401.1 - 0.6 9.3 14.6 0.064 12.4 0.5 4.2 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.4 KEZ43401.1 - 4.4 7.0 16.8 0.15 11.8 0.3 4.1 3 1 1 4 4 4 0 Uncharacterised protein family UPF0547 Actin PF00022.14 KEZ43403.1 - 7.2e-100 334.1 0.0 8.5e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Actin SGL PF08450.7 KEZ43404.1 - 0.0023 17.3 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region DOMON PF03351.12 KEZ43404.1 - 0.0061 16.4 0.1 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 DOMON domain FYVE PF01363.16 KEZ43405.1 - 0.058 13.2 3.1 0.13 12.1 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.6 KEZ43405.1 - 0.067 12.9 0.3 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.1 KEZ43405.1 - 0.13 12.0 7.4 0.24 11.2 5.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 KEZ43405.1 - 0.45 10.2 7.3 1.1 8.9 5.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ43405.1 - 0.59 9.9 7.6 1.3 8.8 5.2 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEZ43405.1 - 0.72 9.9 9.7 0.17 11.9 4.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S49_N PF08496.5 KEZ43405.1 - 1 9.1 9.7 3.1 7.5 3.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-P11 PF03854.9 KEZ43405.1 - 7 6.2 6.7 5.3 6.5 0.0 2.5 3 0 0 3 3 3 0 P-11 zinc finger RNA_pol_Rpc4 PF05132.9 KEZ43405.1 - 8.1 6.4 7.7 29 4.6 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Sugar_tr PF00083.19 KEZ43406.1 - 3.1e-75 253.4 13.1 1.4e-72 244.7 8.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43406.1 - 1.2e-30 106.4 26.1 1.7e-30 105.9 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ43406.1 - 0.031 14.0 0.6 5.6 6.8 0.1 2.7 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.11 KEZ43407.1 - 7.7e-20 70.8 33.5 7.7e-20 70.8 23.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43407.1 - 3.4e-11 42.3 0.6 3.4e-11 42.3 0.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KEZ43407.1 - 2e-06 26.5 13.5 1.4e-05 23.6 0.0 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 KEZ43407.1 - 0.094 12.5 0.0 0.094 12.5 0.0 3.0 4 0 0 4 4 4 0 MFS_1 like family MFS_3 PF05977.8 KEZ43407.1 - 1.9 6.5 18.8 0.68 7.9 0.7 2.9 2 1 1 3 3 3 0 Transmembrane secretion effector Bac_surface_Ag PF01103.18 KEZ43408.1 - 1.9e-34 119.5 0.0 2.5e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 KEZ43409.1 - 4.5e-27 94.2 0.1 8.6e-27 93.2 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme MFS_1 PF07690.11 KEZ43410.1 - 5.4e-27 94.4 33.1 5.4e-27 94.4 23.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43410.1 - 6.9e-15 54.5 9.8 6.9e-15 54.5 6.8 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter DUF412 PF04217.8 KEZ43410.1 - 0.055 13.2 6.0 0.76 9.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF412 DUF4577 PF15145.1 KEZ43412.1 - 0.022 14.6 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Ank_2 PF12796.2 KEZ43413.1 - 4.8e-22 78.1 0.2 8.2e-22 77.3 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43413.1 - 1.5e-21 75.0 3.5 1.2e-07 31.2 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KEZ43413.1 - 1.7e-21 75.7 7.2 4.3e-11 42.6 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ43413.1 - 5.3e-21 74.5 2.7 3.6e-11 43.2 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43413.1 - 4.9e-17 60.3 0.9 5.3e-05 23.0 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat DUF3328 PF11807.3 KEZ43414.1 - 5.1e-09 36.1 0.6 6.6e-09 35.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KEZ43415.1 - 7.6e-23 81.3 0.1 8.9e-23 81.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sorb PF02208.11 KEZ43416.1 - 0.00034 19.9 0.9 2.5 7.5 0.0 4.0 4 0 0 4 4 4 2 Sorbin homologous domain IPI_T4 PF11634.3 KEZ43416.1 - 0.045 13.6 5.9 1.7 8.5 0.1 3.4 1 1 3 4 4 4 0 Nuclease inhibitor from bacteriophage T4 DUF3328 PF11807.3 KEZ43417.1 - 7.8e-45 153.2 0.4 1.2e-44 152.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KEZ43418.1 - 1.4e-52 178.5 3.6 1.8e-52 178.1 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.1 KEZ43419.1 - 4.8e-21 75.1 0.0 9.7e-21 74.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43419.1 - 1.8e-08 34.1 0.0 3.4e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ43419.1 - 1.1e-07 32.4 0.0 5.3e-06 26.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ43419.1 - 9.4e-06 26.0 0.0 0.00027 21.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43419.1 - 1e-05 25.9 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ43419.1 - 0.0011 18.3 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KEZ43419.1 - 0.0015 18.0 0.0 0.0033 16.9 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ43419.1 - 0.0036 17.6 0.0 0.015 15.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ43419.1 - 0.0037 17.2 0.0 0.12 12.3 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KEZ43419.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KEZ43419.1 - 0.037 13.0 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase DUF1996 PF09362.5 KEZ43420.1 - 2.6e-75 253.0 0.6 3.3e-75 252.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Tyrosinase PF00264.15 KEZ43421.1 - 3.7e-41 141.7 0.1 4.7e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2231 PF09990.4 KEZ43422.1 - 4.9 7.5 10.2 2.9 8.2 5.1 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) TPR_1 PF00515.23 KEZ43423.1 - 2e-14 52.5 2.2 0.0003 20.2 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ43423.1 - 3e-12 46.3 3.4 0.0022 17.8 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ43423.1 - 5e-12 44.7 5.8 0.0027 17.5 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ43423.1 - 1.2e-10 40.3 3.9 0.012 15.3 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ43423.1 - 3.1e-10 39.5 2.8 5.9e-05 22.6 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 KEZ43423.1 - 9.6e-10 38.8 1.1 0.027 15.1 0.2 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ43423.1 - 1.1e-09 38.4 8.9 0.038 14.3 0.5 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 KEZ43423.1 - 3.2e-09 36.7 3.8 1.5e-05 25.0 0.8 4.8 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KEZ43423.1 - 1.7e-08 34.3 1.8 0.76 10.5 0.0 6.5 5 1 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 KEZ43423.1 - 9.9e-07 28.9 0.5 6.4e-05 23.0 0.0 3.7 3 1 1 4 4 3 1 AAA domain NACHT PF05729.7 KEZ43423.1 - 5.6e-06 26.1 0.2 2.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEZ43423.1 - 4.6e-05 23.4 0.0 0.0003 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.1 KEZ43423.1 - 6.4e-05 22.4 7.7 0.31 10.9 0.0 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ43423.1 - 9e-05 22.2 3.8 21 5.2 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 KEZ43423.1 - 0.0013 18.5 0.2 11 6.3 0.0 4.8 5 0 0 5 5 3 0 PPR repeat TPR_6 PF13174.1 KEZ43423.1 - 0.0043 17.4 14.4 0.35 11.4 0.0 6.9 7 0 0 7 7 5 1 Tetratricopeptide repeat RNA_helicase PF00910.17 KEZ43423.1 - 0.0087 16.2 0.0 0.041 14.0 0.0 2.2 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.9 KEZ43423.1 - 0.014 15.1 0.0 6.8 6.4 0.0 3.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TPR_17 PF13431.1 KEZ43423.1 - 0.035 14.2 1.2 51 4.4 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Mg_chelatase PF01078.16 KEZ43423.1 - 0.057 12.5 0.0 0.44 9.6 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 KEZ43423.1 - 0.072 13.2 0.0 1.7 8.8 0.0 3.0 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEZ43423.1 - 0.086 13.1 0.0 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KEZ43423.1 - 0.094 13.5 0.1 0.7 10.7 0.0 2.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ43423.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PPR_3 PF13812.1 KEZ43423.1 - 0.11 12.8 0.2 3.5 8.1 0.1 3.8 3 0 0 3 3 1 0 Pentatricopeptide repeat domain HET PF06985.6 KEZ43427.1 - 4.2e-22 78.8 8.2 4.2e-22 78.8 5.7 3.5 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FA_synthesis PF02504.10 KEZ43427.1 - 0.28 10.0 0.4 0.44 9.3 0.3 1.2 1 0 0 1 1 1 0 Fatty acid synthesis protein CoA_trans PF01144.18 KEZ43428.1 - 1.3e-95 318.7 0.5 2.4e-57 193.5 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KEZ43428.1 - 0.013 15.1 0.2 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF3455 PF11937.3 KEZ43429.1 - 8.9e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Glyco_hydro_15 PF00723.16 KEZ43430.1 - 1.5e-93 313.8 0.1 3.4e-93 312.6 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KEZ43430.1 - 2.9e-30 103.7 2.3 5.8e-30 102.7 0.1 2.4 2 0 0 2 2 2 1 Starch binding domain ERG4_ERG24 PF01222.12 KEZ43431.1 - 1e-149 498.7 16.4 1.3e-149 498.4 11.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Glyco_hydro_18 PF00704.23 KEZ43433.1 - 1e-19 71.2 3.2 1.6e-19 70.5 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 KEZ43433.1 - 0.008 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) CBM_14 PF01607.19 KEZ43433.1 - 0.06 13.2 0.7 0.15 12.0 0.5 1.6 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain AAA PF00004.24 KEZ43434.1 - 1.3e-16 60.9 0.0 2.3e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ43434.1 - 5e-05 24.1 0.0 0.00036 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEZ43434.1 - 0.00015 21.9 0.2 0.0024 18.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ43434.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ43434.1 - 0.0023 17.9 0.2 0.049 13.6 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 KEZ43434.1 - 0.0031 16.9 0.0 0.0079 15.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KEZ43434.1 - 0.0055 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEZ43434.1 - 0.011 15.4 0.0 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEZ43434.1 - 0.015 14.3 0.0 0.061 12.3 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KEZ43434.1 - 0.11 11.6 0.0 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Zot PF05707.7 KEZ43434.1 - 0.12 11.8 0.0 0.79 9.1 0.0 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) p450 PF00067.17 KEZ43435.1 - 1.9e-26 92.5 0.0 1.7e-18 66.4 0.0 3.1 1 1 1 2 2 2 2 Cytochrome P450 Beta-lactamase PF00144.19 KEZ43436.1 - 3.6e-24 85.4 0.3 7.1e-24 84.4 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase UDPGT PF00201.13 KEZ43437.1 - 6.9e-12 44.6 0.0 9.6e-12 44.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ABC2_membrane PF01061.19 KEZ43438.1 - 5.3e-80 267.5 61.2 1.8e-43 148.1 17.2 3.2 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KEZ43438.1 - 1.5e-36 124.1 0.9 1.7e-32 111.1 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.22 KEZ43438.1 - 2.1e-36 125.2 0.0 1.9e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KEZ43438.1 - 3.5e-16 59.0 0.0 1e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEZ43438.1 - 2.7e-08 33.4 0.0 2.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KEZ43438.1 - 1.1e-07 31.2 41.1 0.00013 21.1 13.6 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 KEZ43438.1 - 1.4e-07 31.5 0.1 0.016 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEZ43438.1 - 2.4e-05 23.6 0.1 0.0007 18.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ43438.1 - 5.7e-05 23.1 0.1 0.0027 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KEZ43438.1 - 0.00013 21.4 0.6 0.032 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 KEZ43438.1 - 0.00019 20.9 0.1 0.0052 16.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 KEZ43438.1 - 0.001 18.3 0.0 0.16 11.1 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KEZ43438.1 - 0.0024 18.6 0.0 0.61 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEZ43438.1 - 0.004 17.3 0.1 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ43438.1 - 0.0068 16.1 0.4 2.7 7.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KEZ43438.1 - 0.0084 16.4 0.0 0.35 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEZ43438.1 - 0.012 15.2 0.9 2.3 7.8 0.2 2.9 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KEZ43438.1 - 0.065 13.1 1.5 0.88 9.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 KEZ43438.1 - 0.073 13.2 0.1 22 5.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 KEZ43438.1 - 0.077 12.9 0.1 1.5 8.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KEZ43438.1 - 0.41 10.0 1.5 6.9 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain GMC_oxred_N PF00732.14 KEZ43439.1 - 9.9e-66 221.8 0.0 1.6e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ43439.1 - 3.9e-35 121.2 0.0 6.1e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ43439.1 - 1.4e-06 27.4 0.0 0.014 14.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ43439.1 - 7.3e-05 21.8 2.2 0.00045 19.2 1.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ43439.1 - 0.0019 18.1 0.1 0.0072 16.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ43439.1 - 0.009 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KEZ43439.1 - 0.011 14.2 0.2 0.061 11.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 KEZ43439.1 - 0.019 15.3 2.1 3 8.3 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KEZ43439.1 - 0.021 14.8 1.4 1.3 9.0 0.0 2.8 2 1 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.11 KEZ43442.1 - 3.2e-40 137.9 32.9 3.2e-40 137.9 22.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43442.1 - 9e-08 31.1 21.2 9e-08 31.1 14.7 3.6 2 2 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 KEZ43442.1 - 1.3e-07 30.2 2.7 1.9e-07 29.6 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cu-oxidase_2 PF07731.9 KEZ43443.1 - 2e-23 82.4 2.1 2.2e-21 75.8 1.7 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEZ43443.1 - 2.6e-22 78.7 0.0 5.8e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Myb_DNA-bind_6 PF13921.1 KEZ43445.1 - 0.00024 21.1 4.2 0.00073 19.6 2.9 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain LysM PF01476.15 KEZ43445.1 - 0.083 12.7 0.1 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 LysM domain AAA_12 PF13087.1 KEZ43447.1 - 1.4e-21 76.7 0.0 2.4e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ43447.1 - 5.1e-10 39.3 0.0 1.4e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ43447.1 - 1.9e-05 24.2 0.1 0.00012 21.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 KEZ43447.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 KEZ43447.1 - 0.0058 16.1 0.0 7.1 6.0 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KEZ43447.1 - 0.027 14.0 0.0 5.3 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KEZ43447.1 - 0.2 11.9 0.3 57 4.0 0.1 3.1 3 0 0 3 3 3 0 AAA domain F-box-like PF12937.2 KEZ43448.1 - 9.8e-06 25.2 0.1 2.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ43448.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.8 1 0 0 1 1 1 0 F-box domain FBA PF04300.8 KEZ43448.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 F-box associated region Nucleoplasmin PF03066.10 KEZ43448.1 - 0.044 13.3 1.3 0.072 12.6 0.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF1996 PF09362.5 KEZ43449.1 - 8.8e-80 267.7 0.4 1.1e-79 267.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.6 KEZ43450.1 - 1.6e-24 86.6 0.0 2.8e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMN_red PF03358.10 KEZ43452.1 - 9e-25 86.9 0.0 1.8e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase F-box-like PF12937.2 KEZ43452.1 - 0.00044 19.9 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ43452.1 - 0.001 18.6 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 F-box domain Rhodanese PF00581.15 KEZ43452.1 - 0.0016 18.7 0.0 0.0043 17.3 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain 2-Hacid_dh_C PF02826.14 KEZ43452.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SBF PF01758.11 KEZ43453.1 - 1.6e-47 161.3 10.1 1.6e-47 161.3 7.0 2.3 3 1 0 3 3 3 1 Sodium Bile acid symporter family Mid2 PF04478.7 KEZ43453.1 - 2.2 7.7 6.3 6.9 6.0 0.9 2.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2061 PF09834.4 KEZ43453.1 - 6.4 7.0 7.4 2.9 8.1 0.2 3.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2061) bZIP_1 PF00170.16 KEZ43454.1 - 0.021 14.7 7.8 0.021 14.7 5.4 1.8 1 1 1 2 2 2 0 bZIP transcription factor POX PF07526.6 KEZ43454.1 - 0.033 14.4 0.2 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Associated with HOX Sugar_tr PF00083.19 KEZ43455.1 - 1e-16 60.6 15.7 3.6e-10 39.0 3.2 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43455.1 - 7.3e-10 38.0 9.8 1.2e-06 27.5 2.5 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily RTA1 PF04479.8 KEZ43456.1 - 6.8e-40 136.9 6.7 1e-39 136.3 4.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3413 PF11893.3 KEZ43456.1 - 0.092 11.6 5.6 0.17 10.7 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) YwiC PF14256.1 KEZ43456.1 - 4.1 7.5 8.2 1.4 9.0 0.4 3.0 2 1 2 4 4 4 0 YwiC-like protein Na_H_Exchanger PF00999.16 KEZ43457.1 - 2.4e-35 121.7 16.9 3.6e-35 121.2 11.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KEZ43457.1 - 0.012 15.5 0.3 0.012 15.5 0.2 2.6 2 0 0 2 2 2 0 YrhC-like protein DUF3267 PF11667.3 KEZ43457.1 - 0.068 13.3 2.9 0.25 11.5 2.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3267) Vma12 PF11712.3 KEZ43457.1 - 4.9 6.8 5.3 9.3 5.9 0.5 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TauD PF02668.11 KEZ43458.1 - 9.4e-29 100.8 0.0 1.2e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEZ43458.1 - 0.017 14.0 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 CsiD Ras PF00071.17 KEZ43460.1 - 6.2e-24 84.2 0.0 1.3e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ43460.1 - 1.5e-09 38.3 0.0 4.1e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEZ43460.1 - 0.0023 17.8 0.0 0.0075 16.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KEZ43460.1 - 0.071 12.5 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_2 PF12679.2 KEZ43461.1 - 1.8 7.3 8.1 0.071 11.9 1.3 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein TRI12 PF06609.8 KEZ43463.1 - 1.3e-25 89.7 22.4 1.6e-25 89.3 15.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KEZ43463.1 - 1.2e-24 86.7 55.3 3.4e-23 81.9 36.6 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 KEZ43464.1 - 2.7e-20 72.9 0.0 3.7e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43464.1 - 3.1e-08 33.6 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43464.1 - 0.00025 20.7 0.0 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 KR domain MFS_1 PF07690.11 KEZ43465.1 - 3.4e-30 104.9 41.4 3.4e-30 104.9 28.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3154 PF11351.3 KEZ43465.1 - 0.64 9.7 4.8 0.16 11.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) Glycos_transf_2 PF00535.21 KEZ43466.1 - 1.5e-12 47.5 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEZ43466.1 - 2.5e-12 47.0 0.3 3.9e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEZ43466.1 - 3.6e-05 23.1 0.3 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Ocular_alb PF02101.10 KEZ43466.1 - 0.025 13.1 0.0 0.056 12.0 0.0 1.5 2 0 0 2 2 2 0 Ocular albinism type 1 protein DoxX PF07681.7 KEZ43466.1 - 0.025 14.9 0.1 0.059 13.8 0.1 1.6 1 1 0 1 1 1 0 DoxX ABC2_membrane_2 PF12679.2 KEZ43467.1 - 0.037 12.8 4.9 0.0089 14.9 1.1 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Transferase PF02458.10 KEZ43468.1 - 3e-15 55.6 0.0 1.1e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Transferase family Peptidase_S15 PF02129.13 KEZ43469.1 - 0.015 14.7 0.4 0.061 12.7 0.2 1.8 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Transferase PF02458.10 KEZ43470.1 - 4.8e-29 101.0 0.0 1.8e-28 99.2 0.0 1.7 1 1 0 1 1 1 1 Transferase family Condensation PF00668.15 KEZ43470.1 - 5.1e-05 22.2 0.0 9.9e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 Condensation domain DUF3382 PF11862.3 KEZ43470.1 - 0.025 14.4 1.0 0.1 12.4 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Pyr_redox_3 PF13738.1 KEZ43472.1 - 1e-22 81.2 0.0 2.4e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ43472.1 - 6.6e-22 77.4 0.7 6e-20 70.9 0.2 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ43472.1 - 9.8e-11 41.5 0.0 3e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ43472.1 - 8e-06 24.9 0.0 0.0016 17.4 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ43472.1 - 0.00041 20.1 0.0 0.035 13.8 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KEZ43472.1 - 0.11 11.4 0.0 4 6.2 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ43472.1 - 0.17 10.9 0.0 1.3 8.0 0.0 2.3 3 0 0 3 3 3 0 Thi4 family Abhydrolase_3 PF07859.8 KEZ43473.1 - 5.1e-26 91.5 0.0 2.4e-25 89.3 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KEZ43473.1 - 9.8e-05 21.7 0.0 0.0015 17.8 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KEZ43473.1 - 0.00025 20.3 0.0 0.061 12.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1640 PF07798.6 KEZ43474.1 - 0.11 12.4 1.4 0.18 11.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ABC_tran_2 PF12848.2 KEZ43474.1 - 0.63 9.9 5.8 1.1 9.1 4.0 1.3 1 0 0 1 1 1 0 ABC transporter bZIP_1 PF00170.16 KEZ43474.1 - 4.5 7.2 17.6 6.2 6.8 10.2 2.4 2 1 0 2 2 2 0 bZIP transcription factor p450 PF00067.17 KEZ43475.1 - 2.4e-29 102.2 0.0 3.1e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.3 KEZ43475.1 - 7e-24 84.2 0.3 1.3e-23 83.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 KEZ43476.1 - 3.9e-18 65.9 2.4 7.6e-18 64.9 1.7 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ43476.1 - 6.3e-11 42.2 0.5 8.6e-11 41.8 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ43476.1 - 4.4e-06 26.6 0.0 7.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pectate_lyase_3 PF12708.2 KEZ43479.1 - 4.9e-63 213.2 2.8 3.2e-52 177.8 0.9 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KEZ43479.1 - 0.00034 20.0 0.7 0.077 12.4 0.1 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Annexin PF00191.15 KEZ43480.1 - 7.1e-48 160.3 2.3 1.5e-13 50.4 0.0 4.3 4 0 0 4 4 4 4 Annexin Spore_III_AF PF09581.5 KEZ43480.1 - 0.048 13.5 0.5 13 5.6 0.0 2.8 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) ADH_zinc_N PF00107.21 KEZ43481.1 - 7.7e-30 103.1 0.7 1.4e-29 102.2 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ43481.1 - 1.6e-19 71.0 0.0 4.1e-19 69.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ43481.1 - 2.4e-11 43.3 0.0 5.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KEZ43481.1 - 0.00035 20.5 0.0 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KEZ43481.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease_2 PF13520.1 KEZ43483.1 - 9.5e-39 133.1 25.9 7.7e-34 116.9 9.8 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KEZ43483.1 - 1.3e-10 40.2 16.5 1.3e-10 40.2 11.5 3.0 2 1 0 2 2 2 2 Amino acid permease BatA PF07584.6 KEZ43483.1 - 0.094 12.9 0.3 0.094 12.9 0.2 3.2 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal F-box PF00646.28 KEZ43484.1 - 1.6e-09 37.1 0.3 1.6e-09 37.1 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KEZ43484.1 - 3.1e-06 26.8 0.6 8.7e-06 25.3 0.4 1.8 1 0 0 1 1 1 1 F-box-like KIF1B PF12423.3 KEZ43484.1 - 0.13 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinesin protein 1B GMC_oxred_N PF00732.14 KEZ43485.1 - 2.2e-60 204.3 0.0 2.8e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ43485.1 - 1.1e-31 110.0 0.0 1.8e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KEZ43485.1 - 5e-05 23.2 0.0 0.00041 20.3 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ43485.1 - 0.0002 20.4 0.3 0.0039 16.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ43485.1 - 0.00024 20.2 0.2 0.00056 19.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KEZ43485.1 - 0.00025 20.0 0.0 0.00045 19.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEZ43485.1 - 0.0032 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEZ43485.1 - 0.015 14.2 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 KEZ43485.1 - 0.025 14.5 0.0 0.073 13.0 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 KEZ43485.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ43485.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase G-alpha PF00503.15 KEZ43486.1 - 3.8e-08 32.4 0.0 0.00024 19.9 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ank_2 PF12796.2 KEZ43487.1 - 9.9e-43 144.4 0.0 2.8e-15 56.4 0.0 4.8 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ43487.1 - 5.1e-30 103.3 1.1 9.9e-11 41.8 0.0 7.0 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 KEZ43487.1 - 7.2e-29 98.1 3.9 7.3e-07 28.6 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEZ43487.1 - 3.4e-27 93.8 3.3 2e-07 31.0 0.0 7.0 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43487.1 - 7.3e-23 78.3 0.6 0.0023 18.0 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Zn_clus PF00172.13 KEZ43487.1 - 0.28 11.1 9.4 0.7 9.8 6.5 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KEZ43488.1 - 3.9e-47 159.9 0.0 4e-25 88.5 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEZ43489.1 - 3e-25 88.6 20.2 5.1e-25 87.9 13.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43489.1 - 8.7e-09 34.4 7.0 1.1e-06 27.5 0.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KEZ43489.1 - 3.9e-05 22.0 3.7 3.9e-05 22.0 2.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.2 KEZ43489.1 - 0.00031 20.4 0.0 0.0007 19.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Flavi_NS4A PF01350.12 KEZ43489.1 - 0.083 12.4 1.8 0.17 11.4 0.0 2.3 2 1 0 2 2 2 0 Flavivirus non-structural protein NS4A LRR_1 PF00560.28 KEZ43489.1 - 3 8.2 5.2 45 4.6 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2235 PF09994.4 KEZ43490.1 - 7.7e-74 248.5 1.4 9.6e-72 241.6 0.4 2.9 2 1 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ribosomal_S2 PF00318.15 KEZ43492.1 - 1.7e-48 164.6 0.0 3.4e-48 163.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S2 HAUS6_N PF14661.1 KEZ43492.1 - 0.18 11.0 2.3 0.32 10.3 1.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Anthrax-tox_M PF09156.5 KEZ43492.1 - 0.77 8.8 3.7 1.1 8.2 2.5 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain FliT PF05400.8 KEZ43492.1 - 0.99 9.8 5.3 1.9 8.9 2.9 2.1 2 0 0 2 2 2 0 Flagellar protein FliT CBS PF00571.23 KEZ43493.1 - 8.8e-42 140.6 8.1 6.7e-11 41.8 0.0 4.9 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KEZ43493.1 - 4.7e-08 32.5 0.0 1.5e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 PB1 domain zf-C2H2 PF00096.21 KEZ43494.1 - 5.3e-09 35.8 18.7 0.00022 21.3 3.7 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEZ43494.1 - 1.2e-08 34.8 10.7 0.00024 21.2 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEZ43494.1 - 0.048 14.0 19.2 0.77 10.2 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger DUF4470 PF14737.1 KEZ43495.1 - 5.1e-07 29.3 0.0 1.8e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 KEZ43495.1 - 0.34 10.8 6.7 0.64 9.9 4.7 1.4 1 0 0 1 1 1 0 MYND finger Cpn60_TCP1 PF00118.19 KEZ43496.1 - 4.6e-148 493.8 0.5 5.5e-148 493.5 0.4 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 KEZ43496.1 - 9.7e-52 174.8 1.3 6.3e-51 172.2 0.0 2.6 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain PCI_Csn8 PF10075.4 KEZ43497.1 - 2.7e-36 124.4 0.0 3.8e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KEZ43497.1 - 1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DNA_ligase_A_M PF01068.16 KEZ43498.1 - 3.3e-49 166.9 0.1 1.6e-46 158.2 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEZ43498.1 - 5.1e-29 101.3 0.0 1.2e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEZ43498.1 - 2.7e-18 66.1 0.0 1e-17 64.3 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 KEZ43498.1 - 0.19 11.4 0.0 0.49 10.0 0.0 1.6 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Adaptin_N PF01602.15 KEZ43499.1 - 2.9e-148 494.4 2.9 4e-148 494.0 2.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KEZ43499.1 - 9.8e-26 90.6 0.7 6.5e-25 88.0 0.0 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEZ43499.1 - 4.4e-18 65.3 0.1 4.4e-07 30.0 0.0 5.1 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KEZ43499.1 - 2.2e-11 42.8 5.5 0.0049 16.8 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KEZ43499.1 - 4e-05 23.9 0.3 1.9 9.0 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat UNC45-central PF11701.3 KEZ43499.1 - 4.1e-05 23.2 0.0 0.0035 16.9 0.0 2.6 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.18 KEZ43499.1 - 0.002 17.8 1.4 1.7 8.5 0.0 5.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KEZ43499.1 - 0.013 14.8 0.0 1.9 7.7 0.0 3.3 2 1 1 3 3 3 0 CLASP N terminal RasGEF_N_2 PF14663.1 KEZ43499.1 - 0.083 12.8 0.1 0.8 9.6 0.0 2.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain AF0941-like PF14591.1 KEZ43499.1 - 0.099 12.7 2.3 0.49 10.4 1.2 2.4 3 0 0 3 3 3 0 AF0941-like BolA PF01722.13 KEZ43500.1 - 5.8e-19 67.8 0.0 6.9e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 KEZ43501.1 - 7e-54 182.9 0.0 8.5e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.6 KEZ43502.1 - 1.3e-25 89.0 0.0 2.6e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 KEZ43502.1 - 9.6e-05 20.9 0.1 0.00013 20.5 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family TPR_11 PF13414.1 KEZ43503.1 - 1.3e-40 136.8 33.6 1.8e-05 24.2 0.0 13.0 7 4 7 14 14 14 11 TPR repeat TPR_16 PF13432.1 KEZ43503.1 - 1.6e-32 111.4 39.0 1.5e-05 25.5 0.1 13.7 11 4 3 15 15 15 8 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ43503.1 - 2.6e-28 96.4 18.3 0.0021 17.6 0.0 15.2 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ43503.1 - 4.9e-28 95.0 34.3 0.017 15.6 0.3 16.9 12 6 5 17 17 16 7 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ43503.1 - 2e-27 92.8 46.0 0.0094 15.7 0.0 17.7 20 0 0 20 20 18 8 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ43503.1 - 8.2e-26 90.1 20.0 0.061 13.6 0.0 12.4 11 1 1 12 12 12 7 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ43503.1 - 3.2e-24 83.0 18.3 0.083 13.1 0.0 16.8 19 0 0 19 19 19 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ43503.1 - 6e-22 77.3 37.6 4.5e-05 23.2 0.0 12.8 9 3 3 13 13 12 6 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ43503.1 - 7.5e-14 50.3 19.1 0.023 14.4 0.0 12.9 14 0 0 14 14 13 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ43503.1 - 2.7e-13 48.6 22.0 0.024 14.4 0.1 13.9 13 1 1 14 14 14 2 Tetratricopeptide repeat Apc3 PF12895.2 KEZ43503.1 - 8.4e-09 35.4 21.3 0.00079 19.5 0.0 8.9 7 2 1 10 10 10 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEZ43503.1 - 9.6e-05 22.5 46.0 1.6 9.3 0.0 15.7 20 0 0 20 20 17 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ43503.1 - 0.005 16.6 13.1 0.032 14.0 0.4 6.0 6 1 0 6 6 5 1 Tetratricopeptide repeat Apc5 PF12862.2 KEZ43503.1 - 0.017 14.9 2.8 6 6.7 0.0 4.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 ChAPs PF09295.5 KEZ43503.1 - 0.056 12.2 0.2 13 4.4 0.0 3.5 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 KEZ43503.1 - 0.067 13.6 34.4 0.33 11.5 0.1 10.6 12 0 0 12 12 9 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ43503.1 - 0.32 11.1 20.9 5.9 7.0 1.0 6.9 8 1 0 8 8 5 0 Tetratricopeptide repeat Cellulase PF00150.13 KEZ43504.1 - 9.1e-11 41.4 0.9 4.4e-07 29.3 0.2 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 KEZ43504.1 - 0.013 14.6 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase Pkinase PF00069.20 KEZ43505.1 - 3e-63 213.4 0.0 4.4e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43505.1 - 2.7e-48 164.2 0.0 4.5e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ43505.1 - 1.4e-07 30.7 0.0 4.6e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEZ43505.1 - 0.018 14.1 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_jaz PF12171.3 KEZ43505.1 - 0.35 11.0 1.2 0.74 10.0 0.8 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_47 PF01532.15 KEZ43506.1 - 1.3e-170 567.9 0.0 1.6e-170 567.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HR1 PF02185.11 KEZ43506.1 - 0.051 13.3 0.9 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 Hr1 repeat ING PF12998.2 KEZ43506.1 - 0.46 10.7 4.5 0.2 11.9 1.1 1.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fig1 PF12351.3 KEZ43507.1 - 1.1e-55 188.3 4.7 1.1e-55 188.3 3.3 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KEZ43507.1 - 1.7e-08 34.2 9.2 2.4e-08 33.7 6.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 KEZ43507.1 - 6.1e-05 22.0 8.2 6.1e-05 22.0 5.7 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 KEZ43507.1 - 0.24 11.6 7.8 0.32 11.2 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4064 PF13273.1 KEZ43507.1 - 7.4 6.7 15.9 0.34 11.0 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) HEAT_EZ PF13513.1 KEZ43508.1 - 0.062 13.8 1.0 7.6 7.1 0.1 2.5 2 1 0 2 2 2 0 HEAT-like repeat Pox_A12 PF04651.8 KEZ43508.1 - 0.073 13.1 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein HEAT PF02985.17 KEZ43508.1 - 0.13 12.4 0.1 3 8.1 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat Cyanate_lyase PF02560.9 KEZ43509.1 - 2.2e-33 113.6 0.0 2.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 KEZ43509.1 - 0.00011 22.2 0.1 0.0002 21.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 KEZ43509.1 - 0.084 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1744 PF08490.7 KEZ43510.1 - 2.6e-136 454.3 0.0 3.6e-136 453.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KEZ43510.1 - 3.4e-60 203.6 0.1 9.8e-60 202.1 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KEZ43510.1 - 5.6e-21 74.8 1.2 1.2e-20 73.7 0.0 2.2 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KEZ43510.1 - 1.4e-08 34.5 0.1 3.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KEZ43510.1 - 5.9e-05 22.9 0.2 0.00022 21.1 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 KEZ43511.1 - 1.7e-28 98.6 0.0 2.7e-28 98.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) Aldose_epim PF01263.15 KEZ43512.1 - 5e-53 180.1 0.0 1.5e-52 178.6 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase VID27 PF08553.5 KEZ43514.1 - 0 1133.5 0.2 0 1133.3 0.2 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Daxx PF03344.10 KEZ43514.1 - 0.24 9.8 13.4 0.35 9.2 9.3 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KEZ43514.1 - 0.37 8.7 13.9 0.56 8.1 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KEZ43514.1 - 0.46 8.3 14.4 0.66 7.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family DDRGK PF09756.4 KEZ43514.1 - 6.5 6.1 16.0 13 5.1 11.1 1.4 1 0 0 1 1 1 0 DDRGK domain Prenylcys_lyase PF07156.9 KEZ43515.1 - 1.8e-29 102.7 0.0 7.1e-29 100.8 0.0 1.8 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KEZ43515.1 - 5.6e-11 42.2 0.0 5.6e-11 42.2 0.0 2.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ43515.1 - 2.7e-05 23.2 0.1 4.6e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ43515.1 - 0.0002 21.1 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KEZ43515.1 - 0.00026 20.2 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KEZ43515.1 - 0.00044 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ43515.1 - 0.0036 17.1 0.1 0.039 13.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ43515.1 - 0.058 12.4 0.5 0.19 10.7 0.1 1.8 2 0 0 2 2 2 0 Thi4 family WSC PF01822.14 KEZ43516.1 - 4.8e-10 39.2 7.4 9e-10 38.3 5.2 1.4 1 0 0 1 1 1 1 WSC domain DUF4366 PF14283.1 KEZ43516.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) CD99L2 PF12301.3 KEZ43516.1 - 0.0088 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 SKG6 PF08693.5 KEZ43516.1 - 0.017 14.4 0.5 0.037 13.3 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KEZ43516.1 - 0.076 11.2 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Elicitin PF00964.12 KEZ43516.1 - 0.091 12.7 1.0 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 Elicitin SseC PF04888.7 KEZ43516.1 - 0.1 11.8 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ADH_zinc_N PF00107.21 KEZ43517.1 - 8.9e-24 83.4 0.0 1.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ43517.1 - 8.1e-08 33.2 0.1 2.2e-07 31.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3681 PF12442.3 KEZ43518.1 - 0.0053 16.9 1.2 0.0065 16.6 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3681) PIF PF05092.7 KEZ43520.1 - 0.21 9.9 4.7 0.27 9.5 3.2 1.1 1 0 0 1 1 1 0 Per os infectivity ECH PF00378.15 KEZ43521.1 - 1.8e-46 158.2 0.1 2.3e-42 144.8 0.1 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Glyco_trans_4_4 PF13579.1 KEZ43521.1 - 0.062 13.4 0.4 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain GMC_oxred_C PF05199.8 KEZ43525.1 - 1.3e-28 100.0 0.0 2.3e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KEZ43525.1 - 7e-28 97.6 0.0 6.2e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ43525.1 - 0.00024 20.0 0.0 0.0016 17.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ43525.1 - 0.0037 17.2 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEZ43525.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ43525.1 - 0.0062 16.6 0.0 0.72 9.8 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ43525.1 - 0.011 14.7 0.4 0.18 10.6 0.2 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ43525.1 - 0.052 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEZ43525.1 - 0.055 12.5 0.1 0.11 11.4 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 KEZ43526.1 - 1.6e-39 135.6 24.7 2.3e-39 135.1 17.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43527.1 - 1.7e-118 396.0 22.7 2.1e-118 395.7 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43527.1 - 7.3e-24 84.1 44.8 3.1e-21 75.4 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ43527.1 - 1e-08 34.0 26.8 0.00013 20.5 6.6 3.8 3 1 0 3 3 3 3 MFS/sugar transport protein DUF3154 PF11351.3 KEZ43527.1 - 0.1 12.3 0.0 6.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3154) MFS_1_like PF12832.2 KEZ43527.1 - 0.23 11.2 8.6 2.8 7.7 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family 7TM-7TMR_HD PF07698.6 KEZ43527.1 - 1.8 7.9 19.0 0.44 9.9 0.1 3.7 3 1 1 4 4 4 0 7TM receptor with intracellular HD hydrolase Cutinase PF01083.17 KEZ43528.1 - 4.4e-41 140.5 0.0 6.3e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KEZ43528.1 - 0.00017 21.1 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KEZ43528.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 KEZ43528.1 - 0.029 14.0 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 KEZ43528.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1858 PF08984.6 KEZ43528.1 - 0.073 12.7 0.0 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) Abhydrolase_5 PF12695.2 KEZ43528.1 - 0.098 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4360 PF14273.1 KEZ43529.1 - 9.2e-11 41.7 0.1 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) GvpH PF05455.6 KEZ43529.1 - 0.01 15.4 0.7 0.016 14.8 0.5 1.3 1 0 0 1 1 1 0 GvpH Pentaxin PF00354.12 KEZ43529.1 - 0.02 14.3 0.2 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 Pentaxin family zf-C2H2_2 PF12756.2 KEZ43530.1 - 1.8e-28 98.6 2.5 1.3e-23 83.0 0.1 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KEZ43530.1 - 0.0033 17.2 0.5 0.0033 17.2 0.4 2.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 KEZ43530.1 - 0.025 14.7 1.7 0.025 14.7 1.2 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEZ43530.1 - 0.038 14.1 3.5 0.46 10.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 KEZ43530.1 - 6.6 7.3 15.6 2.2 8.7 0.8 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sec7 PF01369.15 KEZ43531.1 - 2.7e-41 141.3 0.0 5e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KEZ43531.1 - 1.4e-18 67.1 0.0 5.2e-18 65.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain DUF1524 PF07510.6 KEZ43532.1 - 4.7e-15 55.6 0.0 5.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KEZ43532.1 - 0.076 12.6 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease APH PF01636.18 KEZ43533.1 - 1.1e-07 31.8 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ43533.1 - 0.0002 20.9 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KEZ43533.1 - 0.062 12.4 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Glyco_hydro_16 PF00722.16 KEZ43534.1 - 4.2e-42 143.5 0.6 9e-42 142.4 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 KAR9 PF08580.5 KEZ43534.1 - 0.28 9.4 10.0 0.36 9.0 6.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF1754 PF08555.5 KEZ43534.1 - 0.37 11.4 3.0 0.63 10.6 2.1 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Sec3_C PF09763.4 KEZ43534.1 - 0.6 8.1 1.7 0.75 7.8 1.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 KEZ43534.1 - 3 6.0 16.2 3.9 5.6 11.2 1.0 1 0 0 1 1 1 0 Transmembrane protein PAP2 PF01569.16 KEZ43535.1 - 9.7e-22 77.0 1.8 9.7e-22 77.0 1.3 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KEZ43535.1 - 0.0075 16.5 1.8 0.016 15.4 0.1 2.3 2 0 0 2 2 2 1 PAP2 superfamily C-terminal YbjM PF11045.3 KEZ43535.1 - 0.19 11.5 3.6 3.4 7.4 0.5 2.4 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae Kinesin PF00225.18 KEZ43536.1 - 3.2e-83 279.2 0.0 4.5e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 KEZ43536.1 - 0.0028 17.5 0.0 0.012 15.5 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 KEZ43536.1 - 0.022 14.4 0.0 4.2 7.2 0.1 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF2673 PF10880.3 KEZ43536.1 - 0.085 12.9 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) AIM24 PF01987.12 KEZ43537.1 - 5e-47 160.1 0.0 6.4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 FHIPEP PF00771.15 KEZ43537.1 - 0.063 11.6 0.0 0.089 11.1 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4402 PF14352.1 KEZ43537.1 - 0.068 13.6 0.7 0.16 12.4 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) MFS_1 PF07690.11 KEZ43538.1 - 7.3e-37 126.8 77.6 2.5e-29 102.1 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ43538.1 - 2.3e-11 42.7 12.2 2.3e-11 42.7 8.5 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 KEZ43538.1 - 2.8e-06 26.2 43.0 0.0033 16.0 15.7 3.7 1 1 3 4 4 4 3 Sugar (and other) transporter MFS_1_like PF12832.2 KEZ43538.1 - 0.0017 18.1 1.7 0.0017 18.1 1.2 3.3 3 0 0 3 3 3 1 MFS_1 like family Formyl_trans_N PF00551.14 KEZ43540.1 - 3.7e-33 114.5 0.0 4.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF2336 PF10098.4 KEZ43540.1 - 0.049 12.8 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) Opi1 PF08618.5 KEZ43541.1 - 0.048 12.5 0.1 0.048 12.5 0.1 1.0 1 0 0 1 1 1 0 Transcription factor Opi1 Glyco_hydro_18 PF00704.23 KEZ43542.1 - 1.7e-45 156.0 0.2 2.2e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2474 PF10617.4 KEZ43543.1 - 0.061 12.9 0.6 0.061 12.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) DUF202 PF02656.10 KEZ43543.1 - 0.09 13.0 7.5 0.51 10.5 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) IncA PF04156.9 KEZ43546.1 - 0.016 14.8 4.6 0.031 13.8 3.2 1.4 1 1 0 1 1 1 0 IncA protein DUF3481 PF11980.3 KEZ43546.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Endothelin PF00322.12 KEZ43546.1 - 0.03 13.5 0.8 0.069 12.3 0.6 1.6 1 0 0 1 1 1 0 Endothelin family DUF1514 PF07438.6 KEZ43546.1 - 0.031 14.1 0.6 0.071 13.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) DivIC PF04977.10 KEZ43546.1 - 0.081 12.4 5.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF2650 PF10853.3 KEZ43546.1 - 3.8 7.0 7.0 9.9 5.7 4.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Pyridoxal_deC PF00282.14 KEZ43547.1 - 1.6e-79 267.0 0.0 2.3e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KEZ43547.1 - 3.1e-05 23.2 0.0 4.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KEZ43547.1 - 3.4e-05 22.7 0.0 6e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GPP34 PF05719.6 KEZ43548.1 - 7.9e-66 222.0 0.3 1.1e-65 221.6 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SURF6 PF04935.7 KEZ43549.1 - 1.3e-49 168.3 46.1 1.3e-49 168.3 32.0 3.5 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 KEZ43549.1 - 6.7e-08 32.4 2.5 6.7e-08 32.4 1.7 7.2 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 HUN PF08729.5 KEZ43550.1 - 5.5e-14 51.7 0.6 1.3e-13 50.5 0.4 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain MFS_1 PF07690.11 KEZ43551.1 - 3.6e-18 65.4 40.0 4.7e-18 65.0 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF2A PF08662.6 KEZ43552.1 - 7.2e-76 254.2 1.0 3.2e-74 248.8 0.0 2.6 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A CDV3 PF15359.1 KEZ43552.1 - 0.0047 16.9 0.5 0.0047 16.9 0.4 2.7 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 Fic PF02661.13 KEZ43553.1 - 7.5e-08 32.9 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family WD40 PF00400.27 KEZ43554.1 - 5.7e-30 102.1 14.7 4.2e-11 42.2 0.2 7.9 7 0 0 7 7 7 3 WD domain, G-beta repeat RelA_SpoT PF04607.12 KEZ43554.1 - 3.8e-09 36.5 0.0 8.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins NACHT PF05729.7 KEZ43554.1 - 1.4e-07 31.3 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ43554.1 - 0.0016 18.4 1.0 0.0074 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ43554.1 - 0.0046 17.1 0.0 0.02 14.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 KEZ43554.1 - 0.005 16.4 0.7 15 5.4 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat KAP_NTPase PF07693.9 KEZ43554.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.17 KEZ43554.1 - 0.28 9.9 0.0 0.51 9.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UNC-93 PF05978.11 KEZ43555.1 - 1.6e-08 34.1 2.9 1.6e-08 34.1 2.0 1.8 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 KEZ43555.1 - 1.8e-08 33.3 10.4 2e-07 29.9 6.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43555.1 - 1.2e-05 24.1 28.2 1.2e-05 24.1 19.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 KEZ43555.1 - 0.075 11.7 9.3 0.0095 14.6 3.5 1.6 2 0 0 2 2 2 0 PUCC protein DAO PF01266.19 KEZ43556.1 - 2.8e-37 128.4 0.0 2.1e-32 112.4 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ43556.1 - 0.0092 15.8 0.0 0.061 13.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2156 PF09924.4 KEZ43556.1 - 0.051 12.3 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) GIDA PF01134.17 KEZ43556.1 - 0.069 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Aldo_ket_red PF00248.16 KEZ43557.1 - 7.6e-53 179.1 0.0 8.9e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 KEZ43559.1 - 6.7e-06 25.9 13.9 1.3e-05 25.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inhibitor_I36 PF03995.8 KEZ43560.1 - 0.037 14.3 0.8 0.065 13.6 0.6 1.4 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Pkinase PF00069.20 KEZ43561.1 - 6.8e-41 140.1 0.0 1.1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43561.1 - 2.4e-19 69.4 0.0 4.9e-19 68.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ43561.1 - 0.0039 16.2 0.0 0.0079 15.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ43561.1 - 0.011 14.8 0.1 0.023 13.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.2 KEZ43562.1 - 1.1e-48 163.5 1.8 4.5e-13 49.3 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43562.1 - 2.2e-40 134.4 0.9 4.7e-09 35.5 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KEZ43562.1 - 1.4e-35 121.0 0.1 4.6e-10 39.7 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43562.1 - 1.7e-31 105.1 0.1 1.2e-06 28.1 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEZ43562.1 - 2.4e-30 103.8 0.9 4.2e-11 42.7 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Aminotran_5 PF00266.14 KEZ43563.1 - 1.1e-32 113.2 0.0 1.3e-30 106.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V AAA_16 PF13191.1 KEZ43565.1 - 2.3e-06 27.7 0.0 1.4e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.2 KEZ43565.1 - 6.8e-06 26.1 0.3 3.7e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEZ43565.1 - 0.008 15.4 0.0 0.024 13.9 0.0 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.7 KEZ43565.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KEZ43565.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase PrgI PF12666.2 KEZ43566.1 - 0.058 13.5 1.2 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 PrgI family protein DUF4401 PF14351.1 KEZ43566.1 - 0.059 12.3 6.6 0.081 11.9 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) VLPT PF07122.6 KEZ43566.1 - 0.096 12.3 0.9 0.17 11.5 0.6 1.4 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) DUF998 PF06197.8 KEZ43566.1 - 0.36 10.1 12.4 0.023 14.0 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) VHS PF00790.14 KEZ43567.1 - 3.3e-46 156.4 0.0 1.4e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KEZ43567.1 - 2.6e-24 85.1 0.3 5.9e-24 83.9 0.2 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KEZ43567.1 - 4.3e-18 65.7 0.0 9.5e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GTP_EFTU PF00009.22 KEZ43568.1 - 4.2e-37 127.3 1.3 1.8e-36 125.3 0.9 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KEZ43568.1 - 1.9e-24 85.6 0.4 5.1e-24 84.2 0.2 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KEZ43568.1 - 4.3e-13 49.1 0.2 4.3e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEZ43568.1 - 1.6e-07 31.2 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 KEZ43568.1 - 6.1e-07 28.9 0.0 1.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 KEZ43568.1 - 7.7e-06 26.3 0.1 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KEZ43568.1 - 9.8e-06 25.1 0.1 2.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KEZ43568.1 - 0.0024 17.1 0.1 0.0056 15.9 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 KEZ43568.1 - 0.0025 17.0 0.1 0.0055 15.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KEZ43568.1 - 0.03 14.1 0.5 8.7 6.1 0.0 3.0 2 1 1 3 3 3 0 Dynamin family PP28 PF10252.4 KEZ43569.1 - 7.8e-25 86.7 17.1 7.8e-25 86.7 11.9 2.9 3 0 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CoA_trans PF01144.18 KEZ43571.1 - 1.4e-98 328.3 1.6 4.5e-59 199.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Nrap PF03813.9 KEZ43572.1 - 1e-266 887.2 0.0 1.2e-266 887.0 0.0 1.0 1 0 0 1 1 1 1 Nrap protein DUF4202 PF13875.1 KEZ43572.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) DUF1918 PF08940.6 KEZ43573.1 - 0.088 12.1 0.3 6.2 6.2 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.16 KEZ43574.1 - 1.8e-55 187.4 0.0 4.8e-55 186.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Beta-TrCP_D PF12125.3 KEZ43574.1 - 0.16 11.5 0.2 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 D domain of beta-TrCP Transglut_core2 PF13369.1 KEZ43575.1 - 4.3e-15 55.4 0.0 9e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 KEZ43575.1 - 2.1e-08 33.7 0.5 5.7e-08 32.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ43575.1 - 5.6e-06 25.8 1.6 1.3e-05 24.7 0.7 2.0 2 0 0 2 2 2 1 F-box domain YccV-like PF08755.6 KEZ43575.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Microtub_assoc PF07989.6 KEZ43576.1 - 2.9e-28 97.4 3.7 2.9e-28 97.4 2.5 14.7 10 5 8 18 18 18 1 Microtubule associated PACT_coil_coil PF10495.4 KEZ43576.1 - 9e-09 35.1 0.1 5.6e-08 32.6 0.1 2.5 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 KEZ43576.1 - 1.7e-05 24.6 5.4 1.7e-05 24.6 3.7 11.7 2 2 8 12 12 12 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 KEZ43576.1 - 6.6e-05 21.5 50.1 6.6e-05 21.5 34.8 7.4 1 1 5 6 6 3 2 Weak chloroplast movement under blue light AAA_13 PF13166.1 KEZ43576.1 - 0.00015 20.4 20.3 0.00015 20.4 14.1 5.5 1 1 4 5 5 5 3 AAA domain ADIP PF11559.3 KEZ43576.1 - 0.00018 21.4 13.0 0.00018 21.4 9.0 12.7 3 3 9 13 13 12 4 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 KEZ43576.1 - 0.00048 18.0 57.9 0.00048 18.0 40.2 7.4 1 1 3 5 5 4 3 Myosin tail Cast PF10174.4 KEZ43576.1 - 0.00052 18.2 61.6 0.00052 18.2 42.7 5.9 1 1 4 5 5 3 2 RIM-binding protein of the cytomatrix active zone TPR_MLP1_2 PF07926.7 KEZ43576.1 - 0.00068 19.3 33.4 0.0011 18.7 11.6 14.1 2 1 13 15 15 13 4 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 KEZ43576.1 - 0.00088 18.0 13.3 0.00088 18.0 9.2 10.8 1 1 12 13 13 10 7 Spc7 kinetochore protein ATG16 PF08614.6 KEZ43576.1 - 0.001 18.9 203.6 0.026 14.3 12.4 11.5 1 1 11 12 12 11 6 Autophagy protein 16 (ATG16) DUF812 PF05667.6 KEZ43576.1 - 0.001 17.6 22.1 0.001 17.6 15.3 7.4 1 1 4 6 6 5 2 Protein of unknown function (DUF812) DUF3166 PF11365.3 KEZ43576.1 - 0.0024 18.2 4.8 0.0024 18.2 3.3 11.6 5 3 8 13 13 12 1 Protein of unknown function (DUF3166) IncA PF04156.9 KEZ43576.1 - 0.0036 16.9 15.2 0.0036 16.9 10.6 11.4 1 1 9 10 10 9 4 IncA protein DUF4200 PF13863.1 KEZ43576.1 - 0.0045 16.9 9.4 0.0045 16.9 6.5 14.0 5 3 6 13 13 10 3 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 KEZ43576.1 - 0.2 10.8 72.2 0.071 12.2 1.1 8.7 1 1 8 10 10 10 0 Reovirus sigma C capsid protein Halo_GVPC PF05465.8 KEZ43576.1 - 0.2 11.6 9.8 12 5.9 0.2 5.6 4 1 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat Filament PF00038.16 KEZ43576.1 - 2.9 7.2 186.6 0.011 15.2 33.6 9.1 1 1 7 8 8 8 0 Intermediate filament protein Peptidase_C14 PF00656.17 KEZ43577.1 - 8.6e-70 235.2 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KEZ43577.1 - 0.18 11.6 0.2 0.95 9.2 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain NACHT PF05729.7 KEZ43579.1 - 1.8e-10 40.6 0.0 4.1e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 KEZ43579.1 - 6.7e-10 39.1 0.0 1.9e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43579.1 - 9.7e-10 37.7 0.3 0.00022 20.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KEZ43579.1 - 1.8e-06 28.3 0.0 5.7e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43579.1 - 7.1e-05 22.6 0.1 0.41 11.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat AAA_16 PF13191.1 KEZ43579.1 - 0.0013 18.7 0.8 0.12 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Ank_5 PF13857.1 KEZ43579.1 - 0.0029 17.8 0.4 0.082 13.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_22 PF13401.1 KEZ43579.1 - 0.036 14.2 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KEZ43579.1 - 0.066 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Whi5 PF08528.6 KEZ43580.1 - 1.7e-10 40.2 0.1 3.2e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.3 KEZ43581.1 - 4.9e-169 562.2 0.0 5.9e-169 561.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KEZ43581.1 - 4.6e-06 26.5 0.1 1.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_2 PF13574.1 KEZ43581.1 - 0.024 14.6 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KEZ43581.1 - 0.025 14.4 0.3 0.045 13.6 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KEZ43581.1 - 0.22 12.0 0.6 0.43 11.1 0.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDP-OH_P_transf PF01066.16 KEZ43582.1 - 3.4e-14 52.9 3.2 7e-14 51.9 2.2 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase tRNA-synt_2b PF00587.20 KEZ43583.1 - 6.6e-44 149.5 0.2 1.1e-43 148.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEZ43583.1 - 2.4e-18 65.8 0.1 5e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KEZ43583.1 - 2.3e-12 46.5 0.0 5.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KEZ43583.1 - 1.4e-11 44.0 0.0 2.9e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Pro-NT_NN PF07421.6 KEZ43583.1 - 0.12 11.9 0.1 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Gar1 PF04410.9 KEZ43584.1 - 2.3e-43 147.3 0.2 2.3e-43 147.3 0.2 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region PH PF00169.24 KEZ43585.1 - 5.9e-09 36.0 0.1 1.4e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 PH domain Prominin PF05478.6 KEZ43585.1 - 0.067 10.7 0.4 0.1 10.1 0.3 1.1 1 0 0 1 1 1 0 Prominin MinC_C PF03775.11 KEZ43585.1 - 0.46 10.1 2.7 0.51 9.9 0.0 2.3 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain DUF2013 PF09431.5 KEZ43586.1 - 7.9e-51 171.4 3.2 7.9e-51 171.4 2.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) IBN_N PF03810.14 KEZ43586.1 - 0.043 13.7 0.4 1.3 8.9 0.4 3.1 3 1 0 3 3 3 0 Importin-beta N-terminal domain LCAT PF02450.10 KEZ43587.1 - 1.7e-96 323.6 0.0 2.1e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 KEZ43587.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Acetyltransf_1 PF00583.19 KEZ43588.1 - 2.6e-17 62.5 0.0 4.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEZ43588.1 - 1.8e-09 37.7 0.0 2.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEZ43588.1 - 2.6e-09 37.1 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEZ43588.1 - 1.5e-08 34.2 0.0 2.2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KEZ43588.1 - 3.5e-07 30.2 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEZ43588.1 - 5.4e-07 29.8 0.0 7.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEZ43588.1 - 0.0039 17.0 0.2 0.0062 16.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEZ43588.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 KEZ43588.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1917 PF08939.5 KEZ43589.1 - 1.2e-54 185.6 0.0 1.9e-54 184.9 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Apc4_WD40 PF12894.2 KEZ43590.1 - 1.5e-05 24.3 0.4 0.15 11.6 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 KEZ43590.1 - 4.8e-05 23.0 2.2 1.8 8.5 0.0 4.8 6 1 0 6 6 6 2 WD domain, G-beta repeat Xpo1 PF08389.7 KEZ43591.1 - 5.9e-07 29.5 2.3 7.1e-05 22.7 0.0 3.4 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 KEZ43591.1 - 1.9e-05 24.4 1.5 0.00027 20.7 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 KEZ43591.1 - 3.8 7.4 6.8 1.7 8.6 0.1 3.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Zn_clus PF00172.13 KEZ43592.1 - 2.5e-06 27.3 11.8 2.5e-06 27.3 8.2 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1645 PF07816.6 KEZ43592.1 - 0.072 13.5 13.7 0.14 12.6 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Sec3_C PF09763.4 KEZ43592.1 - 0.11 10.5 1.5 4.2 5.3 0.7 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec3 Tom37_C PF11801.3 KEZ43592.1 - 0.35 10.7 1.9 9.3 6.0 0.0 2.8 3 0 0 3 3 3 0 Tom37 C-terminal domain SR-25 PF10500.4 KEZ43592.1 - 0.8 9.1 22.3 1.6 8.1 15.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KEZ43592.1 - 1.9 8.5 22.1 3.8 7.6 15.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Macoilin PF09726.4 KEZ43592.1 - 7 4.8 8.8 10 4.2 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Sec23_trunk PF04811.10 KEZ43594.1 - 2.5e-71 239.8 0.0 3.6e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEZ43594.1 - 4.9e-24 83.7 0.0 4.4e-23 80.6 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 KEZ43594.1 - 7.3e-18 63.8 6.2 1.2e-17 63.1 4.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 KEZ43594.1 - 9.5e-18 64.5 0.1 1.9e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KEZ43594.1 - 2.7e-10 39.7 0.0 5.8e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat TEX12 PF15219.1 KEZ43594.1 - 0.66 9.9 2.0 1 9.3 0.5 1.9 2 0 0 2 2 2 0 Testis-expressed 12 Pkinase PF00069.20 KEZ43595.1 - 1.5e-74 250.4 0.0 2e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43595.1 - 8.5e-32 110.2 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ43595.1 - 0.00059 18.8 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ43595.1 - 0.0021 17.1 0.1 0.0036 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEZ43595.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Gag_p6 PF08705.6 KEZ43595.1 - 0.018 15.0 0.1 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Gag protein p6 Seadorna_VP7 PF07387.6 KEZ43595.1 - 0.058 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.14 KEZ43595.1 - 0.063 12.6 0.2 0.22 10.8 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain TLD PF07534.11 KEZ43596.1 - 1.9e-22 79.7 0.1 3.3e-13 49.8 0.2 2.2 2 0 0 2 2 2 2 TLD Pex14_N PF04695.8 KEZ43596.1 - 0.36 10.8 0.1 0.36 10.8 0.0 2.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Evr1_Alr PF04777.8 KEZ43597.1 - 7.2e-30 102.7 0.6 2.5e-28 97.8 0.1 2.1 2 0 0 2 2 2 2 Erv1 / Alr family TPP_enzyme_N PF02776.13 KEZ43598.1 - 1.1e-27 96.5 0.0 1.8e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ43598.1 - 9.4e-27 93.4 0.0 2.6e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KEZ43598.1 - 2e-14 53.4 0.2 4.9e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KEZ43598.1 - 0.032 12.9 0.1 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component THUMP PF02926.12 KEZ43599.1 - 1.2e-06 28.4 0.7 4.6e-06 26.5 0.3 2.1 1 1 0 1 1 1 1 THUMP domain SGT1 PF07093.6 KEZ43600.1 - 9e-134 447.0 18.7 2.4e-132 442.3 13.0 2.0 1 1 0 1 1 1 1 SGT1 protein SMC_N PF02463.14 KEZ43601.1 - 3.1e-25 88.7 0.0 6.5e-25 87.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KEZ43601.1 - 7.8e-17 62.2 0.3 7.8e-17 62.2 0.2 5.5 3 1 1 4 4 3 2 AAA domain AAA_21 PF13304.1 KEZ43601.1 - 1.2e-06 28.7 0.0 7.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KEZ43601.1 - 0.0008 18.5 0.1 0.0022 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 KEZ43601.1 - 0.00082 19.2 0.0 0.0037 17.1 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KEZ43601.1 - 0.0023 17.4 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KEZ43601.1 - 0.0095 15.1 6.5 0.53 9.3 0.0 3.6 3 1 1 4 4 4 2 Reovirus sigma C capsid protein AAA_22 PF13401.1 KEZ43601.1 - 0.043 13.9 1.4 3.5 7.7 0.0 3.2 2 0 0 2 2 2 0 AAA domain rve_3 PF13683.1 KEZ43601.1 - 0.053 13.0 0.1 0.31 10.5 0.0 2.4 1 0 0 1 1 1 0 Integrase core domain ABC_tran PF00005.22 KEZ43601.1 - 0.11 12.7 0.1 0.11 12.7 0.1 4.3 3 2 0 3 3 2 0 ABC transporter AAA_13 PF13166.1 KEZ43601.1 - 4.4 5.6 70.8 2.2 6.6 13.9 5.8 4 2 2 6 6 6 0 AAA domain COQ9 PF08511.6 KEZ43602.1 - 8.8e-29 98.8 0.1 1.4e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 COQ9 DUF3645 PF12359.3 KEZ43602.1 - 0.015 14.3 0.1 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) RRM_1 PF00076.17 KEZ43603.1 - 2.1e-46 155.4 0.0 4.9e-16 58.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ43603.1 - 1.2e-36 124.5 0.0 1.7e-12 47.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ43603.1 - 9.1e-23 79.8 0.0 3.5e-07 29.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEZ43603.1 - 0.0001 22.0 0.1 0.27 11.0 0.0 3.4 3 1 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.3 KEZ43603.1 - 0.00063 19.4 0.0 5.3 6.8 0.0 3.5 3 1 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 KEZ43603.1 - 0.00089 18.6 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain PknH_C PF14032.1 KEZ43603.1 - 0.13 11.8 0.1 33 3.9 0.0 2.9 3 0 0 3 3 3 0 PknH-like extracellular domain SRP14 PF02290.10 KEZ43604.1 - 3e-25 87.9 0.2 5.7e-25 87.0 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF4449 PF14613.1 KEZ43604.1 - 0.038 13.9 0.5 0.049 13.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) UPF0193 PF05250.6 KEZ43604.1 - 0.087 12.3 1.2 0.12 11.8 0.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0193) Pyr_redox_dim PF02852.17 KEZ43605.1 - 3.9e-41 139.5 0.0 1.4e-40 137.7 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KEZ43605.1 - 3.8e-38 131.3 16.4 2.1e-37 128.9 10.7 3.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ43605.1 - 3.1e-23 81.9 12.4 9.3e-21 74.0 1.2 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ43605.1 - 1.3e-09 37.6 0.1 1.3e-09 37.6 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ43605.1 - 1.5e-09 37.7 4.7 1e-05 25.4 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEZ43605.1 - 9.8e-09 34.5 9.8 1.1e-07 31.0 2.9 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KEZ43605.1 - 4.2e-08 32.4 10.8 2.3e-07 30.0 2.3 3.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.1 KEZ43605.1 - 4.8e-08 33.2 3.5 0.00012 22.2 1.0 2.8 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ43605.1 - 2.1e-07 30.2 6.3 2e-05 23.8 0.2 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KEZ43605.1 - 3.5e-06 26.1 19.9 0.00015 20.7 1.5 4.0 2 2 2 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KEZ43605.1 - 4.6e-05 22.5 0.4 0.14 11.0 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KEZ43605.1 - 5.9e-05 21.7 16.0 0.00012 20.7 1.6 4.0 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.7 KEZ43605.1 - 0.001 18.1 1.4 0.0049 15.8 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KEZ43605.1 - 0.0031 17.1 4.9 0.65 9.5 0.2 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 KEZ43605.1 - 0.01 14.9 11.4 0.25 10.3 1.0 2.8 2 1 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 KEZ43605.1 - 1.6 9.0 8.1 8.9 6.6 1.0 3.1 2 2 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KEZ43605.1 - 6.1 6.4 8.6 1.2 8.8 0.5 2.6 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FA_desaturase PF00487.19 KEZ43606.1 - 9.4e-35 120.2 28.0 1.6e-34 119.5 19.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KEZ43606.1 - 3.1e-13 49.2 0.0 1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.3 KEZ43607.1 - 1.3e-82 275.3 7.2 1.3e-82 275.3 5.0 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KEZ43607.1 - 2e-46 156.3 0.0 1.9e-43 146.7 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KEZ43607.1 - 6.3e-11 41.3 0.8 2.4e-05 24.0 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 KEZ43607.1 - 1.4e-08 34.8 0.2 0.00029 21.0 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KEZ43607.1 - 1.5e-08 34.8 4.0 1.8e-05 25.0 0.0 5.3 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 KEZ43607.1 - 3.9e-05 23.5 2.2 0.14 12.0 0.0 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KEZ43607.1 - 0.002 17.8 0.0 0.22 11.4 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat TPR_11 PF13414.1 KEZ43608.1 - 7.3e-30 102.4 9.8 1.5e-09 37.3 0.0 7.1 5 2 2 7 7 7 5 TPR repeat DnaJ PF00226.26 KEZ43608.1 - 2.5e-24 84.7 2.2 2.5e-24 84.7 1.5 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 KEZ43608.1 - 4e-24 82.5 10.8 0.0017 18.1 0.1 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ43608.1 - 1.1e-23 83.3 8.5 7.7e-07 29.6 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ43608.1 - 4e-22 76.8 6.0 0.00028 20.3 0.0 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ43608.1 - 4.2e-17 61.1 8.3 0.0091 16.5 0.2 7.0 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ43608.1 - 2.9e-14 51.6 1.4 0.0081 15.8 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ43608.1 - 1.3e-13 50.5 7.9 6.5e-05 22.7 0.4 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ43608.1 - 2e-11 42.7 3.4 0.081 12.7 0.1 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ43608.1 - 6.9e-11 41.8 14.9 0.48 11.0 0.1 8.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ43608.1 - 7.9e-11 41.7 12.6 0.034 14.0 0.0 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ43608.1 - 6.9e-10 39.1 6.0 0.16 12.2 0.0 6.0 3 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ43608.1 - 1.1e-08 34.6 2.2 0.013 15.6 0.0 6.8 8 1 1 9 9 8 2 Tetratricopeptide repeat DUF3775 PF12616.3 KEZ43608.1 - 0.00093 18.9 0.2 0.028 14.2 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3775) Spore_SspJ PF09575.5 KEZ43608.1 - 0.049 13.8 0.2 3.1 8.0 0.0 3.4 3 0 0 3 3 3 0 Small spore protein J (Spore_SspJ) Cse1 PF08506.5 KEZ43608.1 - 0.08 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Cse1 TPR_4 PF07721.9 KEZ43608.1 - 0.21 12.1 4.3 71 4.2 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat APG9 PF04109.11 KEZ43610.1 - 2.9e-155 516.7 0.4 4.2e-155 516.2 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_carr PF00153.22 KEZ43610.1 - 2.3e-37 126.5 10.5 2.1e-21 75.4 0.1 4.5 3 2 1 4 4 4 3 Mitochondrial carrier protein COG6 PF06419.6 KEZ43611.1 - 3.2e-203 676.3 3.9 3.6e-203 676.1 2.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.11 KEZ43611.1 - 0.011 14.5 0.4 0.032 13.0 0.3 1.7 1 0 0 1 1 1 0 RmuC family COG2 PF06148.6 KEZ43611.1 - 0.075 12.8 3.6 0.094 12.5 0.7 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4164 PF13747.1 KEZ43611.1 - 0.2 11.8 6.1 2.2 8.5 0.2 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4164) Ribosomal_S17 PF00366.15 KEZ43612.1 - 0.04 13.9 0.1 0.095 12.7 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S17 Med15 PF09606.5 KEZ43612.1 - 0.043 12.0 75.1 0.058 11.6 52.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Daxx PF03344.10 KEZ43612.1 - 0.065 11.7 31.7 0.11 10.9 22.0 1.3 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 KEZ43612.1 - 1.1 7.4 48.3 1.7 6.7 33.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 KEZ43612.1 - 9 5.5 36.9 13 5.0 25.6 1.2 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 KEZ43612.1 - 9.8 4.1 42.8 14 3.7 29.7 1.1 1 0 0 1 1 1 0 Utp14 protein EMG1 PF03587.9 KEZ43613.1 - 1.8e-11 43.7 0.0 2.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Cys_Met_Meta_PP PF01053.15 KEZ43614.1 - 9.8e-35 119.5 0.0 1.5e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3439 PF11921.3 KEZ43614.1 - 0.033 13.9 0.8 0.066 12.9 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DnaJ PF00226.26 KEZ43615.1 - 4.1e-25 87.2 0.4 4.1e-25 87.2 0.3 2.8 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.3 KEZ43615.1 - 2.4e-10 40.2 10.3 3.7e-09 36.4 2.7 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ43615.1 - 2.2e-09 37.1 7.3 7.3e-09 35.5 0.6 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KEZ43615.1 - 9.6e-07 28.8 7.3 0.0011 19.0 1.9 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KEZ43615.1 - 8.3e-05 22.7 5.2 0.018 15.3 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ43615.1 - 0.00099 19.2 3.4 0.67 10.4 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger ELF PF03317.8 KEZ43615.1 - 0.41 9.8 5.3 4.1 6.6 0.1 2.2 2 0 0 2 2 2 0 ELF protein Peptidase_C54 PF03416.14 KEZ43616.1 - 2.9e-50 170.9 0.0 2e-28 99.3 0.0 2.2 1 1 1 2 2 2 2 Peptidase family C54 Histone PF00125.19 KEZ43617.1 - 9.1e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEZ43617.1 - 3.8e-05 23.6 0.0 9.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KEZ43617.1 - 0.00021 21.5 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KEZ43617.1 - 0.0033 16.1 2.0 0.004 15.8 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KEZ43617.1 - 0.0086 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF1018 PF06252.7 KEZ43617.1 - 0.021 15.3 0.6 0.029 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 KEZ43618.1 - 8.8e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEZ43618.1 - 1.3e-05 25.1 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2-oxoacid_dh PF00198.18 KEZ43619.1 - 1.1e-98 329.1 0.3 5.8e-60 202.4 0.1 2.2 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEZ43619.1 - 1.1e-18 66.6 3.7 2.4e-18 65.5 1.5 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme S4_2 PF13275.1 KEZ43619.1 - 0.0009 18.7 0.1 1 8.9 0.0 3.0 2 0 0 2 2 2 2 S4 domain DUF3614 PF12267.3 KEZ43619.1 - 0.011 16.0 5.1 0.22 11.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.1 KEZ43619.1 - 0.015 14.9 1.8 1.6 8.4 0.1 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like S4 PF01479.20 KEZ43619.1 - 0.049 13.0 0.6 12 5.4 0.1 2.7 2 0 0 2 2 2 0 S4 domain GCV_H PF01597.14 KEZ43619.1 - 0.066 12.9 0.3 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein CorA PF01544.13 KEZ43621.1 - 4.7e-05 22.5 0.1 6.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Caudo_TAP PF02413.12 KEZ43621.1 - 0.00084 19.5 0.2 0.0014 18.7 0.2 1.3 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein DUF4239 PF14023.1 KEZ43621.1 - 0.023 14.0 0.6 0.045 13.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Nsp1_C PF05064.8 KEZ43621.1 - 0.059 13.0 0.6 2.9 7.5 0.4 2.2 1 1 0 1 1 1 0 Nsp1-like C-terminal region FtsX PF02687.16 KEZ43621.1 - 0.067 12.9 2.1 0.1 12.3 1.5 1.3 1 0 0 1 1 1 0 FtsX-like permease family Oxidored_q2 PF00420.19 KEZ43621.1 - 0.24 11.0 1.8 0.73 9.4 1.2 1.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Methyltransf_18 PF12847.2 KEZ43622.1 - 4.1e-11 43.4 0.0 7.1e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ43622.1 - 4.7e-08 32.9 0.0 7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ43622.1 - 1.1e-05 25.7 0.0 2.7e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43622.1 - 2.8e-05 24.4 0.0 6.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KEZ43622.1 - 6.6e-05 23.6 0.0 0.00025 21.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KEZ43622.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KEZ43622.1 - 0.00038 20.8 0.0 0.0016 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43622.1 - 0.003 17.1 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ43622.1 - 0.0032 16.6 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KEZ43622.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KEZ43622.1 - 0.033 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GCD14 PF08704.5 KEZ43622.1 - 0.05 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.15 KEZ43622.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KEZ43622.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4396 PF14342.1 KEZ43623.1 - 5.1e-44 149.7 6.5 6.5e-44 149.4 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) VanZ PF04892.7 KEZ43623.1 - 0.082 12.8 0.1 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 VanZ like family ADH_N PF08240.7 KEZ43624.1 - 2.2e-21 75.6 2.3 3.3e-21 75.0 0.3 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ43624.1 - 2.2e-17 62.7 0.4 3.5e-17 62.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KEZ43624.1 - 0.00013 21.5 0.5 0.00027 20.5 0.2 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KEZ43624.1 - 0.00014 21.0 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KEZ43624.1 - 0.0028 17.2 0.2 0.0046 16.5 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 KEZ43624.1 - 0.0041 16.7 0.6 0.0065 16.1 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KEZ43624.1 - 0.014 14.8 0.4 0.021 14.2 0.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 KEZ43624.1 - 0.016 15.0 0.6 0.032 14.1 0.4 1.4 1 0 0 1 1 1 0 short chain dehydrogenase LIM PF00412.17 KEZ43624.1 - 0.018 15.0 0.4 0.039 14.0 0.3 1.5 1 0 0 1 1 1 0 LIM domain XdhC_C PF13478.1 KEZ43624.1 - 0.02 15.1 0.1 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 KEZ43624.1 - 0.042 13.8 0.6 0.087 12.8 0.4 1.5 1 0 0 1 1 1 0 TrkA-N domain Sulfatase PF00884.18 KEZ43625.1 - 3.9e-65 220.0 0.0 7.8e-65 219.0 0.0 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KEZ43625.1 - 0.0028 17.0 0.1 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KEZ43625.1 - 0.067 13.4 1.2 2.5 8.3 0.6 2.8 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF229 PF02995.12 KEZ43625.1 - 0.17 10.2 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.19 KEZ43626.1 - 3.7e-75 253.2 22.2 4.4e-75 252.9 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43626.1 - 9e-15 54.2 19.0 9e-15 54.2 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ43626.1 - 0.017 13.5 28.5 0.013 13.9 5.0 3.7 2 2 2 4 4 4 0 MFS/sugar transport protein TPP_enzyme_N PF02776.13 KEZ43627.1 - 2e-37 128.3 0.0 6e-37 126.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEZ43627.1 - 3.6e-22 78.5 0.9 1.5e-21 76.6 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ43627.1 - 3.7e-21 75.3 0.0 7.3e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Fungal_trans PF04082.13 KEZ43627.1 - 4e-07 29.1 0.1 9.1e-07 28.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_1_N PF00056.18 KEZ43628.1 - 7.3e-48 161.9 0.1 1e-47 161.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEZ43628.1 - 1.1e-31 109.9 0.0 2.7e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 KEZ43628.1 - 0.00054 19.4 1.4 0.0016 17.8 1.0 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.11 KEZ43628.1 - 0.0029 16.9 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase F420_oxidored PF03807.12 KEZ43628.1 - 0.0053 17.1 0.3 0.011 16.1 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KEZ43628.1 - 0.018 13.9 0.9 0.026 13.4 0.6 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KEZ43628.1 - 0.049 13.9 0.1 0.095 12.9 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 KEZ43628.1 - 0.058 13.3 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 KEZ43628.1 - 0.073 12.8 0.3 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 ThiF family ADH_N PF08240.7 KEZ43629.1 - 3.8e-29 100.6 0.4 6.1e-29 99.9 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ43629.1 - 4.1e-27 94.2 0.2 8e-27 93.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ43629.1 - 0.0042 16.2 0.2 0.0069 15.5 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glucokinase PF02685.11 KEZ43629.1 - 0.034 12.9 0.2 0.05 12.3 0.2 1.3 1 0 0 1 1 1 0 Glucokinase CoA_binding_2 PF13380.1 KEZ43629.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 CoA binding domain HET PF06985.6 KEZ43630.1 - 1.5e-27 96.4 0.2 2.5e-27 95.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEZ43631.1 - 8.2e-130 423.4 25.5 1.5e-16 60.4 0.1 9.6 4 4 5 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43631.1 - 2.1e-124 399.6 49.3 3.6e-10 39.1 0.0 19.4 19 0 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 KEZ43631.1 - 2e-95 311.6 29.5 1.2e-11 44.7 0.0 14.1 6 3 7 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43631.1 - 1.8e-91 290.7 29.3 5.6e-06 26.0 0.0 19.1 19 0 0 19 19 19 15 Ankyrin repeat Ank_5 PF13857.1 KEZ43631.1 - 7.1e-90 293.0 38.1 8.2e-11 41.7 0.1 13.7 5 4 8 14 14 14 13 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ43631.1 - 3e-10 40.0 0.0 8.5e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ43631.1 - 1.1e-07 31.9 0.2 4.9e-07 29.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 KEZ43631.1 - 0.039 13.6 0.2 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KEZ43631.1 - 0.11 12.7 0.9 0.68 10.1 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.1 KEZ43631.1 - 0.36 11.1 20.6 1.4 9.2 10.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 KEZ43631.1 - 2.3 6.0 10.1 5.3 4.8 7.0 1.5 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KEZ43631.1 - 2.5 7.6 13.1 0.83 9.1 5.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 KEZ43631.1 - 7.2 6.2 14.5 0.59 9.8 5.8 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_3 PF07859.8 KEZ43632.1 - 2.4e-25 89.3 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KEZ43632.1 - 3.1e-22 78.7 0.0 4.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KEZ43632.1 - 1.8e-07 31.2 0.1 3.4e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ43632.1 - 7.5e-07 29.0 0.1 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ43632.1 - 0.0032 16.7 0.0 0.014 14.6 0.0 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family Cyt-b5 PF00173.23 KEZ43632.1 - 0.1 12.4 0.5 11 5.9 0.0 2.9 3 0 0 3 3 3 0 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 KEZ43635.1 - 9.9e-35 119.9 0.0 1.4e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43635.1 - 2.9e-08 33.1 0.1 7.1e-06 25.2 0.0 3.4 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KEZ43635.1 - 1 9.0 4.6 1.3 8.7 0.1 2.7 4 0 0 4 4 4 0 Phosphotransferase enzyme family Lipase_GDSL PF00657.17 KEZ43636.1 - 6e-16 58.9 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ43636.1 - 2.9e-12 47.1 0.0 5.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Arrestin_N PF00339.24 KEZ43636.1 - 3.5e-09 36.6 0.0 6.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KEZ43636.1 - 9.2e-08 32.2 0.0 2.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 KEZ43636.1 - 0.00042 19.8 0.0 0.0017 17.9 0.0 2.0 2 1 0 2 2 2 1 Arrestin_N terminal like Lipase_GDSL_3 PF14606.1 KEZ43636.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Podoplanin PF05808.6 KEZ43636.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Podoplanin CFEM PF05730.6 KEZ43636.1 - 1.2 9.0 6.1 2.4 8.0 4.3 1.5 1 0 0 1 1 1 0 CFEM domain 7TM_GPCR_Str PF10326.4 KEZ43637.1 - 0.00045 19.4 2.3 0.00045 19.4 1.6 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Str DUF3366 PF11846.3 KEZ43637.1 - 0.79 9.5 3.6 0.92 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) HemY_N PF07219.8 KEZ43637.1 - 3.3 7.3 5.0 0.85 9.2 0.2 2.4 3 0 0 3 3 3 0 HemY protein N-terminus DnaJ PF00226.26 KEZ43638.1 - 1.3e-20 72.8 1.8 1.3e-20 72.8 1.2 2.7 3 1 0 3 3 3 1 DnaJ domain zf-B_box PF00643.19 KEZ43638.1 - 0.05 13.5 3.3 0.077 12.9 2.3 1.3 1 0 0 1 1 1 0 B-box zinc finger YvrJ PF12841.2 KEZ43638.1 - 0.37 10.1 0.9 12 5.2 0.1 2.4 2 0 0 2 2 2 0 YvrJ protein family Prominin PF05478.6 KEZ43638.1 - 0.67 7.4 3.5 1 6.7 2.4 1.2 1 0 0 1 1 1 0 Prominin HET PF06985.6 KEZ43639.1 - 4.9e-29 101.2 0.1 1.2e-28 100.0 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DLH PF01738.13 KEZ43639.1 - 2.4e-11 43.3 0.0 4.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ43639.1 - 0.0081 15.9 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1338 PF07063.8 KEZ43640.1 - 1.6e-84 283.5 0.0 2.2e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Zn_clus PF00172.13 KEZ43640.1 - 9.9e-10 38.1 6.5 1.9e-09 37.2 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KEZ43641.1 - 3.5e-26 91.2 0.0 1.8e-25 88.9 0.0 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ43641.1 - 1.7e-11 45.1 0.0 4.5e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ43641.1 - 1.4e-08 34.4 0.0 3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain COesterase PF00135.23 KEZ43642.1 - 7.2e-33 114.0 0.0 7.9e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_3 PF01494.14 KEZ43643.1 - 1.4e-07 30.9 0.0 1.9e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 KEZ43643.1 - 0.0049 15.7 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase PFU PF09070.6 KEZ43643.1 - 0.05 13.6 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Fructosamin_kin PF03881.9 KEZ43644.1 - 7.8e-35 120.2 0.0 1e-34 119.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEZ43644.1 - 2.9e-05 23.9 0.0 3.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FGGY_N PF00370.16 KEZ43645.1 - 6.6e-63 212.2 0.0 8.6e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KEZ43645.1 - 9e-54 182.0 6.1 3.8e-52 176.8 4.2 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1647 PF07801.6 KEZ43645.1 - 0.18 11.2 0.0 0.48 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Fungal_trans PF04082.13 KEZ43646.1 - 2.2e-10 39.8 0.1 3.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ43646.1 - 8.9e-08 31.9 11.1 2.1e-07 30.6 7.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KEZ43647.1 - 1e-31 109.8 0.0 1.5e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ43647.1 - 4.5e-08 33.2 0.1 4.3e-05 23.5 0.1 2.7 1 1 2 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KEZ43647.1 - 2.6e-06 27.5 0.0 0.00012 22.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEZ43647.1 - 4e-05 23.5 0.0 6.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ43647.1 - 8.3e-05 23.3 0.2 0.00025 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KEZ43647.1 - 0.0002 21.0 0.0 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 KEZ43647.1 - 0.00021 21.3 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 KEZ43647.1 - 0.00026 20.8 0.0 0.00053 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ43647.1 - 0.00028 20.5 0.1 0.0025 17.5 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 KEZ43647.1 - 0.00039 19.5 0.0 0.00084 18.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KEZ43647.1 - 0.0011 19.3 0.0 0.0025 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KEZ43647.1 - 0.002 17.1 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 KEZ43647.1 - 0.0026 17.7 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KEZ43647.1 - 0.0037 16.4 0.0 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_10 PF12846.2 KEZ43647.1 - 0.0038 16.7 0.1 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain IstB_IS21 PF01695.12 KEZ43647.1 - 0.0041 16.5 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein SF3a60_bindingd PF12108.3 KEZ43647.1 - 0.0046 16.4 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Mg_chelatase PF01078.16 KEZ43647.1 - 0.0066 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KEZ43647.1 - 0.0093 14.7 0.1 0.031 12.9 0.0 1.8 1 1 1 2 2 2 1 TIP49 C-terminus Zeta_toxin PF06414.7 KEZ43647.1 - 0.013 14.6 0.1 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 KEZ43647.1 - 0.014 14.9 0.0 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KEZ43647.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEZ43647.1 - 0.018 14.7 0.0 0.57 9.8 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 KEZ43647.1 - 0.062 12.8 0.0 0.099 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ43647.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IPT PF01745.11 KEZ43647.1 - 0.069 12.3 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase Rad17 PF03215.10 KEZ43647.1 - 0.094 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 KEZ43647.1 - 0.1 11.5 0.1 0.27 10.1 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 KEZ43647.1 - 0.13 11.1 0.0 0.29 9.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Ank PF00023.25 KEZ43648.1 - 1.8e-102 330.4 19.3 2.9e-08 33.1 0.0 13.2 13 0 0 13 13 13 13 Ankyrin repeat Ank_2 PF12796.2 KEZ43648.1 - 7.4e-102 333.8 15.4 4.6e-23 81.3 0.6 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ43648.1 - 1.8e-76 244.3 4.3 2.1e-05 24.3 0.0 13.3 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 KEZ43648.1 - 3.3e-69 228.1 4.0 1.5e-10 41.2 0.1 7.7 5 2 1 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ43648.1 - 1.2e-58 193.8 22.5 6.5e-06 26.2 0.0 12.7 1 1 12 13 13 13 12 Ankyrin repeats (many copies) Clr5 PF14420.1 KEZ43648.1 - 1e-11 44.5 0.6 1.9e-11 43.6 0.4 1.5 1 0 0 1 1 1 1 Clr5 domain Rbsn PF11464.3 KEZ43648.1 - 0.0014 18.1 0.0 24 4.5 0.0 5.2 6 0 0 6 6 6 0 Rabenosyn Rab binding domain DUF1843 PF08898.5 KEZ43648.1 - 0.0037 17.2 6.8 1.1 9.3 0.0 5.6 6 0 0 6 6 6 1 Domain of unknown function (DUF1843) CorA PF01544.13 KEZ43649.1 - 5.8e-06 25.5 1.4 1.1e-05 24.6 0.2 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein LXG PF04740.7 KEZ43650.1 - 0.016 15.0 1.2 0.016 15.0 0.8 1.7 2 0 0 2 2 2 0 LXG domain of WXG superfamily HTH_37 PF13744.1 KEZ43650.1 - 0.033 13.9 0.3 0.08 12.7 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3717 PF12512.3 KEZ43650.1 - 0.12 12.0 0.5 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) AAA_27 PF13514.1 KEZ43651.1 - 0.012 13.3 1.2 0.02 12.6 0.8 1.3 1 0 0 1 1 1 0 AAA domain PLDc_N PF13396.1 KEZ43652.1 - 8.9e-13 47.6 5.9 1.4e-12 47.0 4.1 1.3 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF2207 PF09972.4 KEZ43652.1 - 0.018 13.6 0.5 0.02 13.4 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MARVEL PF01284.18 KEZ43652.1 - 0.055 13.3 2.1 0.067 13.0 1.4 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF3951 PF13131.1 KEZ43652.1 - 0.1 12.3 0.1 0.1 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Pox_A14 PF05767.7 KEZ43652.1 - 0.88 9.5 3.9 1.2 9.1 2.5 1.4 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4064 PF13273.1 KEZ43652.1 - 0.92 9.6 7.2 15 5.7 6.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) SdpI PF13630.1 KEZ43652.1 - 1.3 8.7 5.0 2.6 7.8 3.5 1.6 1 0 0 1 1 1 0 SdpI/YhfL protein family DIM PF08194.7 KEZ43652.1 - 1.3 9.0 3.5 0.46 10.4 0.3 1.9 2 0 0 2 2 2 0 DIM protein DUF2042 PF09743.4 KEZ43653.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Fungal_trans PF04082.13 KEZ43654.1 - 1.7e-05 23.8 0.7 2.5e-05 23.3 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ43655.1 - 2e-38 132.0 54.4 2e-38 132.0 37.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily K_trans PF02705.11 KEZ43657.1 - 4.2e-182 606.2 14.2 5e-182 605.9 9.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter NACHT PF05729.7 KEZ43658.1 - 3.1e-08 33.4 0.2 1.4e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.2 KEZ43658.1 - 2e-06 28.0 0.0 0.0095 16.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) AAA_16 PF13191.1 KEZ43658.1 - 7.2e-05 22.8 0.0 0.0016 18.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ43658.1 - 0.00041 20.5 0.2 0.0026 17.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.1 KEZ43658.1 - 0.0006 19.8 0.0 0.12 12.6 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 KEZ43658.1 - 0.0015 18.2 0.0 0.027 14.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat NB-ARC PF00931.17 KEZ43658.1 - 0.0017 17.3 0.1 0.062 12.1 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.1 KEZ43658.1 - 0.016 15.9 0.0 0.086 13.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain Ank_5 PF13857.1 KEZ43658.1 - 0.03 14.5 0.1 8.9 6.7 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Mg_chelatase PF01078.16 KEZ43658.1 - 0.058 12.5 0.0 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KEZ43658.1 - 0.061 12.5 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 KEZ43658.1 - 0.074 12.4 1.1 0.25 10.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KEZ43658.1 - 0.078 13.1 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_4 PF13637.1 KEZ43658.1 - 0.12 12.9 0.1 24 5.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) SNF2_N PF00176.18 KEZ43659.1 - 8e-43 146.3 0.0 9.6e-38 129.6 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain zf-RING_5 PF14634.1 KEZ43659.1 - 0.00028 20.5 2.9 0.00028 20.5 2.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KEZ43659.1 - 0.0017 17.9 2.1 0.0017 17.9 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KEZ43659.1 - 0.0035 17.1 1.4 0.011 15.5 1.0 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KEZ43659.1 - 0.0046 16.7 3.2 0.011 15.5 2.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.1 KEZ43659.1 - 0.081 12.6 2.3 0.23 11.2 1.6 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger ResIII PF04851.10 KEZ43659.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 KEZ43659.1 - 0.34 10.9 7.6 0.028 14.4 1.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KEZ43659.1 - 2.1 7.9 10.7 0.26 10.9 4.1 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2427 PF10348.4 KEZ43660.1 - 6.2e-09 35.3 2.2 1.5e-08 34.1 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 KEZ43660.1 - 3e-08 33.5 12.0 3e-08 33.5 8.3 2.0 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.14 KEZ43660.1 - 0.0039 17.2 3.8 0.0039 17.2 2.6 2.0 1 1 0 2 2 2 1 Ferric reductase like transmembrane component SdpI PF13630.1 KEZ43660.1 - 0.013 15.1 10.4 0.058 13.1 0.2 2.9 2 1 0 2 2 2 0 SdpI/YhfL protein family DUF2627 PF11118.3 KEZ43660.1 - 4.9 7.3 7.5 0.71 10.0 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2627) APH PF01636.18 KEZ43661.1 - 2.5e-10 40.4 0.0 4.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.23 KEZ43665.1 - 1.1e-42 146.7 0.0 2.1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KEZ43665.1 - 5.2e-09 35.8 0.3 0.0019 18.0 0.0 3.5 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 KEZ43665.1 - 1.6e-05 24.7 4.6 1.6e-05 24.7 3.2 2.7 2 0 0 2 2 2 1 Chitin recognition protein DUF3142 PF11340.3 KEZ43665.1 - 0.0088 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) BNR PF02012.15 KEZ43666.1 - 0.63 10.1 2.8 6 7.1 0.2 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat F-box-like PF12937.2 KEZ43667.1 - 0.019 14.6 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like Kinesin PF00225.18 KEZ43668.1 - 1.2e-60 205.0 0.0 1.7e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Ish1 PF10281.4 KEZ43668.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Fungal_trans_2 PF11951.3 KEZ43669.1 - 2.1e-09 36.4 3.7 5.2e-09 35.1 2.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ43669.1 - 9.4e-06 25.4 9.3 9.4e-06 25.4 6.5 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEZ43670.1 - 1.7e-27 96.1 25.6 1.7e-27 96.1 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3082 PF11282.3 KEZ43671.1 - 0.088 12.8 2.6 0.15 12.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) COX14 PF14880.1 KEZ43671.1 - 0.35 10.5 4.7 8.4 6.1 1.8 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c assembly VIT1 PF01988.14 KEZ43672.1 - 1.6e-16 60.4 0.8 2.3e-16 59.9 0.5 1.3 1 0 0 1 1 1 1 VIT family Phosphoesterase PF04185.9 KEZ43673.1 - 9.1e-34 117.2 1.8 3.9e-33 115.1 1.3 1.7 1 1 0 1 1 1 1 Phosphoesterase family DUF4419 PF14388.1 KEZ43674.1 - 2e-59 201.2 0.0 3.9e-44 151.0 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) RRM_1 PF00076.17 KEZ43674.1 - 5e-21 74.1 0.0 8.3e-14 50.9 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ43674.1 - 4.1e-19 68.3 0.0 8.6e-10 38.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ43674.1 - 6.1e-14 51.6 0.0 7.5e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M20 PF01546.23 KEZ43677.1 - 1.9e-11 43.8 0.1 3.8e-11 42.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEZ43677.1 - 3e-06 26.9 0.0 7.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain NACHT PF05729.7 KEZ43678.1 - 2.5e-06 27.2 0.1 1.3e-05 24.8 0.1 2.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ43678.1 - 3.6e-05 23.8 5.0 4.3e-05 23.5 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEZ43678.1 - 0.00056 20.0 0.6 0.073 13.2 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KEZ43678.1 - 0.0023 18.7 0.0 0.022 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEZ43678.1 - 0.0029 17.9 0.0 0.013 15.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEZ43678.1 - 0.0078 16.5 0.2 0.035 14.4 0.1 2.1 1 0 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.13 KEZ43678.1 - 0.0081 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KEZ43678.1 - 0.0087 15.6 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF927 PF06048.6 KEZ43678.1 - 0.015 14.6 1.2 0.11 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF927) AAA_10 PF12846.2 KEZ43678.1 - 0.016 14.6 0.0 0.048 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 KEZ43678.1 - 0.029 13.8 0.2 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KEZ43678.1 - 0.038 12.8 0.3 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 KEZ43678.1 - 0.058 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEZ43678.1 - 0.099 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEZ43678.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 KEZ43678.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.9 2 1 0 2 2 1 0 AAA domain DUF87 PF01935.12 KEZ43678.1 - 2.3 7.9 12.9 0.96 9.2 0.6 3.7 2 1 1 3 3 3 0 Domain of unknown function DUF87 Methyltransf_2 PF00891.13 KEZ43679.1 - 2.4e-32 112.0 0.0 3.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KEZ43679.1 - 0.00039 20.9 0.0 0.00075 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ43680.1 - 4e-19 68.8 0.0 6.5e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43680.1 - 1.6e-07 31.7 0.0 2.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ43680.1 - 2.1e-06 28.2 0.0 2.6e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ43680.1 - 3.3e-06 27.4 0.0 2.4e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43680.1 - 6.1e-06 25.8 0.0 6.7e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ43680.1 - 0.00091 18.3 0.0 0.0043 16.1 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KEZ43680.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KEZ43680.1 - 0.029 13.4 0.0 0.19 10.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ43680.1 - 0.035 14.4 0.0 0.13 12.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 KEZ43680.1 - 0.051 12.6 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 KEZ43680.1 - 0.12 11.6 0.0 0.28 10.3 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase MTS PF05175.9 KEZ43680.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ43680.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain APH PF01636.18 KEZ43681.1 - 2.7e-13 50.2 0.0 6.3e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ43681.1 - 0.003 17.1 0.0 0.006 16.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase PRD_Mga PF08270.6 KEZ43681.1 - 0.052 12.8 0.4 0.16 11.2 0.1 1.8 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain Abhydrolase_6 PF12697.2 KEZ43682.1 - 0.00074 19.4 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEZ43682.1 - 0.0011 18.3 0.0 0.0027 17.0 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.7 KEZ43682.1 - 0.0045 16.6 0.1 0.19 11.4 0.1 2.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ43682.1 - 0.022 14.8 0.0 1.9 8.6 0.0 3.5 5 0 0 5 5 5 0 AAA domain AAA_17 PF13207.1 KEZ43682.1 - 0.082 13.7 1.0 2 9.2 0.6 2.9 1 1 0 1 1 1 0 AAA domain DUF1933 PF09147.5 KEZ43682.1 - 0.12 11.7 0.1 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) PGAP1 PF07819.8 KEZ43682.1 - 0.14 11.6 0.1 0.4 10.2 0.1 1.7 1 1 0 1 1 1 0 PGAP1-like protein LCAT PF02450.10 KEZ43682.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HET PF06985.6 KEZ43683.1 - 3.5e-36 124.4 1.3 6.5e-36 123.5 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEZ43683.1 - 0.00045 20.4 0.1 0.31 11.4 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEZ43683.1 - 0.0011 19.1 0.0 3.2 8.1 0.0 4.6 2 1 2 4 4 4 1 Ankyrin repeats (many copies) DAO PF01266.19 KEZ43684.1 - 1.1e-44 152.8 0.1 1.4e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ43684.1 - 6.5e-06 25.9 0.1 0.0072 16.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEZ43684.1 - 0.00019 21.3 0.1 0.67 9.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ43684.1 - 0.00036 20.6 0.0 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ43684.1 - 0.00078 18.4 0.1 0.28 10.0 0.0 2.5 2 1 1 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ43684.1 - 0.0012 18.7 0.0 0.0038 17.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEZ43684.1 - 0.0045 15.9 0.3 0.013 14.3 0.1 1.8 2 1 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 KEZ43684.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KEZ43684.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 ThiF family MFS_1 PF07690.11 KEZ43685.1 - 1.3e-32 112.9 27.5 1.3e-32 112.9 19.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.16 KEZ43686.1 - 3.4e-72 243.7 0.2 2.1e-71 241.0 0.2 2.1 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.13 KEZ43686.1 - 6.9e-16 57.9 0.0 1.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain IU_nuc_hydro PF01156.14 KEZ43687.1 - 9e-28 97.3 0.0 1.1e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Daxx PF03344.10 KEZ43689.1 - 0.00078 18.0 11.6 0.00096 17.7 8.1 1.1 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 KEZ43689.1 - 0.025 12.5 21.3 0.033 12.1 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family Adeno_E3_CR2 PF02439.10 KEZ43689.1 - 0.036 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SDA1 PF05285.7 KEZ43689.1 - 0.055 12.7 17.9 0.076 12.2 12.4 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 KEZ43689.1 - 0.1 10.9 20.6 0.14 10.5 14.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 KEZ43689.1 - 0.12 11.0 0.4 0.12 10.9 0.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF605 PF04652.11 KEZ43689.1 - 0.14 11.5 9.0 0.17 11.2 6.2 1.1 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 KEZ43689.1 - 0.21 9.5 12.0 0.27 9.2 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C4H2 PF10146.4 KEZ43689.1 - 0.37 10.7 1.9 9.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein BSP_II PF05432.6 KEZ43689.1 - 5.8 6.1 26.3 0.03 13.5 9.8 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Atrophin-1 PF03154.10 KEZ43689.1 - 6 4.8 13.8 7.6 4.5 9.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF2146 PF10220.4 KEZ43689.1 - 6.7 4.5 6.3 8.2 4.2 4.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF1510 PF07423.6 KEZ43689.1 - 9.7 5.4 15.3 15 4.8 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ank_2 PF12796.2 KEZ43690.1 - 8.4e-13 48.4 1.6 4.8e-05 23.6 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43690.1 - 7.1e-09 35.0 1.2 0.059 13.2 0.2 5.8 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 KEZ43690.1 - 2.5e-08 33.3 6.6 0.2 11.9 0.0 6.2 6 1 1 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 KEZ43690.1 - 1.1e-06 28.9 5.5 0.017 15.5 0.2 5.1 3 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ43690.1 - 6.4e-05 23.0 6.5 6.8 7.0 0.0 6.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) CorA PF01544.13 KEZ43691.1 - 3.8e-33 114.7 0.1 4.9e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 KEZ43692.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF4430 PF14478.1 KEZ43692.1 - 0.033 14.2 0.1 0.083 12.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) RdRP PF05183.7 KEZ43695.1 - 3.7e-92 309.9 0.0 3e-72 244.1 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase AAA_11 PF13086.1 KEZ43695.1 - 2.6e-44 151.5 0.8 2.1e-42 145.3 0.6 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KEZ43695.1 - 9.9e-31 106.6 0.3 2.9e-25 88.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KEZ43695.1 - 4.6e-13 48.7 0.3 1.9e-12 46.7 0.2 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KEZ43695.1 - 8.9e-13 48.2 0.0 2.5e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KEZ43695.1 - 2.6e-07 30.4 0.1 3.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KEZ43695.1 - 8.9e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Helicase ResIII PF04851.10 KEZ43695.1 - 5.3e-05 23.1 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 KEZ43695.1 - 5.7e-05 22.5 0.1 0.00032 20.1 0.1 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 KEZ43695.1 - 9.9e-05 21.8 0.2 0.00036 20.0 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 KEZ43695.1 - 0.00036 19.8 0.1 0.0037 16.5 0.1 2.2 1 1 0 1 1 1 1 PhoH-like protein BACK PF07707.10 KEZ43695.1 - 0.00046 19.9 1.0 0.001 18.8 0.2 2.0 2 0 0 2 2 1 1 BTB And C-terminal Kelch UvrD_C_2 PF13538.1 KEZ43695.1 - 0.0034 17.4 0.0 0.0087 16.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 KEZ43695.1 - 0.021 14.1 0.3 0.39 10.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 KEZ43695.1 - 0.023 14.8 0.4 0.12 12.5 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 KEZ43695.1 - 0.027 14.2 0.9 2.2 8.0 0.1 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain AAA_16 PF13191.1 KEZ43695.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KEZ43695.1 - 0.066 13.3 0.3 0.45 10.6 0.2 2.4 1 1 0 1 1 1 0 AAA domain Nucleos_tra2_C PF07662.8 KEZ43696.1 - 6.5e-67 225.0 5.6 6.5e-67 225.0 3.9 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KEZ43696.1 - 2e-18 66.4 5.1 2e-18 66.4 3.5 3.1 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KEZ43696.1 - 0.012 15.4 8.4 0.012 15.4 5.8 4.0 4 1 0 4 4 4 0 Nucleoside recognition DUF872 PF05915.7 KEZ43697.1 - 0.12 12.2 2.7 0.11 12.3 0.7 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Myco_arth_vir_N PF09610.5 KEZ43697.1 - 0.26 11.2 5.0 2.2 8.3 0.2 2.5 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) HET PF06985.6 KEZ43698.1 - 3.3e-09 37.0 0.0 5.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 KEZ43700.1 - 3e-32 110.8 2.3 2.7e-14 53.2 0.7 5.3 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 KEZ43700.1 - 1.3e-25 90.0 0.0 2.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.1 KEZ43700.1 - 2.3e-23 79.9 9.2 2.2e-05 24.2 0.0 9.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 KEZ43700.1 - 1.7e-21 76.1 7.2 2.6e-09 37.3 0.1 8.6 6 3 4 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.25 KEZ43700.1 - 6.6e-21 73.0 16.1 0.00016 21.2 0.1 8.3 8 0 0 8 8 8 5 Ankyrin repeat Pkinase_Tyr PF07714.12 KEZ43700.1 - 1.1e-19 70.5 0.0 2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.1 KEZ43700.1 - 1.3e-15 57.0 12.7 8.8e-08 32.1 0.3 7.6 4 3 3 7 7 7 4 Ankyrin repeats (many copies) APH PF01636.18 KEZ43700.1 - 0.0018 18.0 0.5 0.0053 16.5 0.3 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEZ43700.1 - 0.0042 16.1 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.1 KEZ43700.1 - 0.043 14.4 0.3 0.21 12.3 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat RIO1 PF01163.17 KEZ43700.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CorA PF01544.13 KEZ43701.1 - 2e-23 82.8 10.7 3.4e-18 65.6 6.2 3.1 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Sugar_tr PF00083.19 KEZ43702.1 - 3.3e-78 263.2 20.7 5.6e-78 262.5 14.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter SET PF00856.23 KEZ43702.1 - 1.4e-14 54.7 0.0 2.7e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 SET domain MFS_1 PF07690.11 KEZ43702.1 - 1.9e-11 43.2 25.7 1.9e-11 43.2 17.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SAF PF08666.7 KEZ43702.1 - 0.024 15.0 0.2 0.066 13.6 0.1 1.7 1 0 0 1 1 1 0 SAF domain CBM_1 PF00734.13 KEZ43703.1 - 9.3e-05 22.0 7.6 0.00019 21.0 5.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Sensor PF13796.1 KEZ43703.1 - 0.014 15.0 1.5 0.021 14.4 1.1 1.2 1 0 0 1 1 1 0 Putative sensor Mito_fiss_reg PF05308.6 KEZ43703.1 - 0.061 12.6 0.1 0.061 12.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF3180 PF11377.3 KEZ43704.1 - 0.0011 18.8 3.3 0.0025 17.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3180) Sigma_reg_N PF13800.1 KEZ43704.1 - 0.046 13.7 0.2 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ATPase_gene1 PF09527.5 KEZ43704.1 - 0.11 12.3 0.2 0.11 12.3 0.1 2.7 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) Intg_mem_TP0381 PF09529.5 KEZ43704.1 - 0.94 8.6 7.6 0.31 10.2 0.3 2.6 2 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) DUF4064 PF13273.1 KEZ43704.1 - 3.1 7.9 5.2 1.2 9.3 0.1 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) DUF485 PF04341.7 KEZ43704.1 - 6.7 6.4 9.0 0.47 10.2 1.0 2.4 1 1 1 3 3 3 0 Protein of unknown function, DUF485 Sod_Cu PF00080.15 KEZ43706.1 - 1.7e-18 67.1 0.2 2.6e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PAN_4 PF14295.1 KEZ43707.1 - 5.7e-06 25.9 0.6 5.7e-06 25.9 0.4 1.7 2 0 0 2 2 2 1 PAN domain PBP1_TM PF14812.1 KEZ43707.1 - 0.014 15.6 4.3 0.076 13.3 3.0 2.2 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDF PF00375.13 KEZ43707.1 - 0.093 11.4 0.2 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family PAT1 PF09770.4 KEZ43707.1 - 5.9 5.0 11.0 8 4.5 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IMS PF00817.15 KEZ43708.1 - 1.5e-42 144.9 0.0 2.7e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEZ43708.1 - 1.9e-13 50.4 0.0 4.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KEZ43708.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF2970 PF11174.3 KEZ43708.1 - 0.071 12.6 0.3 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) TrkH PF02386.11 KEZ43709.1 - 5.6e-73 245.5 2.6 5.4e-67 225.8 0.0 2.7 2 1 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.11 KEZ43709.1 - 0.56 9.9 7.6 0.056 13.1 1.2 2.4 2 0 0 2 2 2 0 Ion channel FKBP_C PF00254.23 KEZ43710.1 - 3.2e-33 113.6 0.0 7.4e-33 112.4 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase AJAP1_PANP_C PF15298.1 KEZ43711.1 - 0.12 12.2 4.9 0.12 12.1 3.4 1.0 1 0 0 1 1 1 0 AJAP1/PANP C-terminus RPEL PF02755.10 KEZ43712.1 - 1.8e-16 58.8 1.3 2.9e-09 35.9 0.5 2.5 2 0 0 2 2 2 2 RPEL repeat Ank_2 PF12796.2 KEZ43713.1 - 1.5e-09 38.0 0.0 2.3e-08 34.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ43713.1 - 8.9e-08 32.4 0.3 4.5e-05 23.8 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43713.1 - 1.7e-07 30.7 0.7 0.2 11.9 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KEZ43713.1 - 1.8e-07 31.1 0.4 4.5e-06 26.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 KEZ43713.1 - 1.3e-06 27.9 3.7 0.32 10.9 0.0 4.4 3 1 0 3 3 3 3 Ankyrin repeat BLOC1_2 PF10046.4 KEZ43713.1 - 0.034 14.2 0.4 0.083 13.0 0.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MARVEL PF01284.18 KEZ43714.1 - 1.6e-12 47.4 23.5 2.1e-12 47.0 16.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1422 PF07226.6 KEZ43714.1 - 1.4 8.6 6.1 2.4 7.9 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1422) DUF1761 PF08570.5 KEZ43714.1 - 1.6 8.7 12.6 7.9 6.5 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) DUF948 PF06103.6 KEZ43714.1 - 3.4 7.5 6.2 20 5.1 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2427 PF10348.4 KEZ43714.1 - 5.1 6.7 9.4 2.5 7.7 5.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF3413 PF11893.3 KEZ43714.1 - 9.3 5.0 12.3 3.7 6.3 6.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) Glyco_hydro_18 PF00704.23 KEZ43715.1 - 1.4e-44 153.0 0.0 1.7e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.27 KEZ43717.1 - 5.1e-05 22.9 3.7 0.013 15.4 0.1 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat CDC45 PF02724.9 KEZ43717.1 - 0.0011 17.1 22.2 0.0015 16.6 15.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 KEZ43717.1 - 0.004 15.1 25.7 0.0054 14.7 17.8 1.1 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.8 KEZ43717.1 - 0.005 16.7 13.4 0.0059 16.5 9.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 KEZ43717.1 - 0.0082 15.3 20.4 0.012 14.7 14.1 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT SDA1 PF05285.7 KEZ43717.1 - 0.011 15.1 25.3 0.015 14.6 17.5 1.1 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 KEZ43717.1 - 0.6 9.4 22.3 0.91 8.8 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KEZ43717.1 - 1.1 8.9 4.6 1.8 8.3 3.2 1.2 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 KEZ43717.1 - 1.7 8.6 12.3 7.8 6.5 8.5 1.9 1 1 0 1 1 1 0 YqfQ-like protein DUF2201_N PF13203.1 KEZ43717.1 - 4.5 6.3 12.5 7.1 5.7 8.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 KEZ43717.1 - 4.9 6.9 9.5 8.6 6.1 6.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.7 KEZ43717.1 - 5.3 5.3 28.8 7.6 4.7 20.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoIIIAH PF12685.2 KEZ43717.1 - 5.4 6.4 14.1 9.2 5.6 9.8 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein PC_rep PF01851.17 KEZ43719.1 - 2.5e-41 137.5 16.9 1.2e-07 31.5 0.0 9.4 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KEZ43719.1 - 8.7e-19 67.5 2.4 7.5e-12 45.3 0.0 6.0 3 2 0 6 6 6 3 HEAT repeats HEAT PF02985.17 KEZ43719.1 - 2.9e-08 33.0 1.1 1.1 9.5 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 KEZ43719.1 - 3.9e-08 33.5 1.1 8.5e-05 22.9 0.0 5.2 5 1 0 5 5 5 1 HEAT-like repeat mRNA_triPase PF02940.10 KEZ43720.1 - 9.3e-50 169.3 0.0 1.3e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain VIT1 PF01988.14 KEZ43721.1 - 6.4 6.1 3.2 14 5.1 2.2 1.5 1 0 0 1 1 1 0 VIT family Transaldolase PF00923.14 KEZ43723.1 - 7.4e-39 133.5 0.0 9.8e-39 133.1 0.0 1.2 1 1 0 1 1 1 1 Transaldolase Myb_DNA-bind_6 PF13921.1 KEZ43724.1 - 3.2e-07 30.3 3.6 3.3e-07 30.2 1.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.3 KEZ43724.1 - 0.054 13.3 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 KEZ43724.1 - 0.17 11.9 1.1 0.35 10.9 0.1 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain Sugar_tr PF00083.19 KEZ43725.1 - 8e-114 380.6 24.3 1.3e-113 379.9 16.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43725.1 - 1.1e-25 90.1 32.3 6.5e-20 71.1 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AhpC-TSA PF00578.16 KEZ43726.1 - 1.5e-31 108.6 0.0 2e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEZ43726.1 - 5.3e-13 48.7 0.0 7.2e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KEZ43726.1 - 7.3e-13 47.9 0.1 1.3e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PIG-S PF10510.4 KEZ43727.1 - 1.6e-149 498.8 1.5 1.9e-149 498.6 1.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Sensor PF13796.1 KEZ43727.1 - 0.1 12.1 5.2 0.32 10.5 0.7 2.7 2 0 0 2 2 2 0 Putative sensor Glyco_hydro_10 PF00331.15 KEZ43728.1 - 2.9e-85 286.1 0.1 3.4e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Abhydrolase_6 PF12697.2 KEZ43729.1 - 7.7e-08 32.4 2.5 0.00065 19.6 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ43729.1 - 2.9e-06 27.0 0.0 5.8e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEZ43729.1 - 0.031 13.7 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AMP-binding PF00501.23 KEZ43730.1 - 7.6e-73 245.2 0.0 9.3e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ43730.1 - 3.2e-14 53.6 0.0 6.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NGP1NT PF08153.7 KEZ43732.1 - 6.1e-49 165.2 0.2 1e-48 164.5 0.2 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KEZ43732.1 - 3.5e-18 65.6 0.0 1.2e-14 54.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ43732.1 - 2.2e-05 23.7 0.0 0.00021 20.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KEZ43732.1 - 0.00058 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KEZ43732.1 - 0.00082 18.8 0.0 0.3 10.5 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEZ43732.1 - 0.0022 17.8 0.0 2 8.1 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 KEZ43732.1 - 0.055 12.7 0.0 0.78 8.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.8 KEZ43732.1 - 0.16 10.7 0.1 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) BUD22 PF09073.5 KEZ43732.1 - 2.7 6.9 26.0 4.4 6.2 18.0 1.2 1 0 0 1 1 1 0 BUD22 ABC2_membrane PF01061.19 KEZ43733.1 - 2.2e-25 89.0 16.0 2.2e-25 89.0 11.1 2.6 2 1 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KEZ43733.1 - 3.7e-24 85.5 0.0 6.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEZ43733.1 - 1.5e-09 38.2 0.0 4.4e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KEZ43733.1 - 4.7e-08 32.4 19.8 5e-08 32.3 12.8 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 KEZ43733.1 - 3.7e-05 23.5 19.8 0.0041 17.1 1.4 4.2 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_25 PF13481.1 KEZ43733.1 - 0.00022 20.6 0.1 0.024 14.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KEZ43733.1 - 0.00037 19.6 0.0 0.79 8.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KEZ43733.1 - 0.0041 16.6 0.1 0.0092 15.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain EGF_2 PF07974.8 KEZ43733.1 - 0.02 15.0 30.6 0.079 13.1 8.5 4.1 3 0 0 3 3 3 0 EGF-like domain DUF258 PF03193.11 KEZ43733.1 - 0.023 13.9 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KEZ43733.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 KEZ43733.1 - 0.032 14.3 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEZ43733.1 - 0.034 14.9 0.0 0.072 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEZ43733.1 - 0.059 13.3 0.5 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 KEZ43733.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 KEZ43733.1 - 0.077 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KEZ43733.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KEZ43733.1 - 0.099 12.9 0.7 0.22 11.8 0.5 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KEZ43733.1 - 0.18 11.4 0.0 0.76 9.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 KEZ43733.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 KEZ43733.1 - 0.45 9.3 15.9 1.4 7.6 11.0 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF1212 PF06738.7 KEZ43733.1 - 2.8 7.3 11.9 1.7 8.0 6.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Aminotran_1_2 PF00155.16 KEZ43734.1 - 8e-41 140.1 0.0 1e-40 139.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ43734.1 - 1.6e-06 27.4 0.0 3.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KEZ43734.1 - 3.4e-06 26.0 0.0 7.5e-06 24.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEZ43734.1 - 1.3e-05 24.4 0.0 2.6e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KEZ43734.1 - 6.7e-05 21.3 0.0 0.0001 20.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 KEZ43734.1 - 0.0061 15.1 0.0 0.007 14.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.8 KEZ43734.1 - 0.018 13.6 0.1 0.038 12.6 0.1 1.5 1 1 0 1 1 1 0 Allinase Asp PF00026.18 KEZ43735.1 - 3.9e-38 131.4 0.0 9.3e-37 126.9 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 KEZ43735.1 - 1.5e-06 27.8 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 KEZ43735.1 - 0.025 14.5 0.2 1.3 8.9 0.1 2.6 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal GTP_EFTU PF00009.22 KEZ43736.1 - 5.9e-55 185.6 0.0 1.6e-54 184.2 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KEZ43736.1 - 2.8e-33 114.0 0.0 5.4e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 KEZ43736.1 - 7.7e-33 112.1 0.0 1.5e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KEZ43736.1 - 1.1e-20 73.2 0.0 2.6e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEZ43736.1 - 6.9e-12 45.3 0.0 1.7e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF3638 PF12340.3 KEZ43736.1 - 0.0096 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) MMR_HSR1 PF01926.18 KEZ43736.1 - 0.031 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Iso_dh PF00180.15 KEZ43737.1 - 1.8e-98 329.7 0.0 2.6e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF423 PF04241.10 KEZ43740.1 - 1.6e-22 79.2 1.1 3.1e-22 78.3 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF202 PF02656.10 KEZ43740.1 - 0.51 10.5 5.2 2.1 8.6 3.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF3185 PF11381.3 KEZ43740.1 - 0.72 9.6 5.2 4.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Flavodoxin_1 PF00258.20 KEZ43741.1 - 1e-10 41.8 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KEZ43741.1 - 1.9e-06 27.4 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KEZ43741.1 - 4.9e-05 22.9 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 KEZ43741.1 - 0.045 13.7 0.0 4.4 7.3 0.0 2.2 1 1 0 2 2 2 0 Flavodoxin domain FAD_binding_3 PF01494.14 KEZ43742.1 - 8.1e-15 54.7 0.0 1.4e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KEZ43742.1 - 7.6e-06 26.2 0.0 2.3e-05 24.6 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ43742.1 - 8.9e-06 25.6 0.0 3e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ43742.1 - 4.4e-05 22.5 0.0 7.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KEZ43742.1 - 0.00039 19.3 0.0 0.00084 18.3 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KEZ43742.1 - 0.00062 19.7 0.1 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ43742.1 - 0.0013 17.2 0.0 0.0018 16.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KEZ43742.1 - 0.007 15.4 0.1 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KEZ43742.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KEZ43742.1 - 0.027 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KEZ43742.1 - 0.035 12.9 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 KEZ43742.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KEZ43742.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KEZ43742.1 - 0.18 10.3 0.3 0.74 8.3 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 KEZ43742.1 - 0.19 10.8 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Peptidase_M24 PF00557.19 KEZ43743.1 - 3.8e-46 157.2 0.0 4.7e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KEZ43743.1 - 7e-05 22.6 4.5 7e-05 22.6 3.1 2.2 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.9 KEZ43744.1 - 1.1e-53 180.7 12.3 1.3e-53 180.5 8.5 1.0 1 0 0 1 1 1 1 Cornichon protein Pec_lyase_C PF00544.14 KEZ43745.1 - 6.4e-48 162.8 2.2 1e-47 162.1 1.5 1.3 1 0 0 1 1 1 1 Pectate lyase DUF600 PF04634.7 KEZ43745.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF600 DUF3336 PF11815.3 KEZ43746.1 - 1.9e-37 127.9 0.0 3.6e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEZ43746.1 - 1.1e-23 84.2 0.0 2.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase adh_short PF00106.20 KEZ43747.1 - 5.7e-27 94.6 4.0 7.3e-27 94.3 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43747.1 - 1.2e-24 87.3 0.0 1.7e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43747.1 - 6e-16 58.6 1.7 8.6e-16 58.1 1.2 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KEZ43747.1 - 0.011 14.4 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ43747.1 - 0.013 14.9 0.1 0.027 13.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 KEZ43748.1 - 4.2e-63 209.7 0.3 8.4e-14 51.6 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43748.1 - 3.5e-42 140.1 0.2 1.1e-05 25.0 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KEZ43748.1 - 8e-40 133.9 7.1 1.5e-06 28.2 0.0 9.1 1 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ43748.1 - 1.4e-36 124.2 9.0 1.1e-07 32.1 0.0 7.5 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43748.1 - 1.8e-36 120.5 0.0 0.00017 21.4 0.0 10.2 10 0 0 10 10 10 6 Ankyrin repeat NACHT PF05729.7 KEZ43748.1 - 6.7e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ43748.1 - 0.0022 18.1 0.0 0.0061 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ43748.1 - 0.015 15.2 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 KEZ43748.1 - 0.027 13.8 0.0 0.099 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KEZ43748.1 - 0.039 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 KEZ43748.1 - 0.054 13.6 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEZ43748.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Chitin_synth_1 PF01644.12 KEZ43749.1 - 5.8e-53 179.0 0.0 1e-52 178.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KEZ43749.1 - 1.7e-15 56.4 0.0 2.6e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 KEZ43749.1 - 1.3e-11 43.9 0.2 1.6e-08 34.1 0.0 3.1 2 1 1 3 3 3 2 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KEZ43749.1 - 1.7e-07 31.1 0.1 1.7e-07 31.1 0.1 2.9 5 0 0 5 5 5 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ43749.1 - 3.8e-07 30.1 0.0 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 EPSP_synthase PF00275.15 KEZ43750.1 - 1.6e-128 428.7 0.0 2.2e-128 428.2 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KEZ43750.1 - 1.3e-99 332.3 1.2 1.3e-99 332.3 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KEZ43750.1 - 3.1e-60 203.6 0.0 7.7e-60 202.3 0.0 1.7 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 KEZ43750.1 - 7e-37 126.7 0.0 1.2e-34 119.5 0.0 2.7 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.6 KEZ43750.1 - 4.5e-23 81.1 0.0 1.4e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 KEZ43750.1 - 3.6e-11 42.8 0.0 6.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 KEZ43750.1 - 4.2e-10 39.8 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 KEZ43750.1 - 0.00065 20.5 0.0 0.0018 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEZ43750.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Histone PF00125.19 KEZ43751.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KEZ43751.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KEZ43751.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEZ43751.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KEZ43751.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KEZ43751.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 KEZ43752.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KEZ43752.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEZ43752.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KEZ43752.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF1227 PF06777.6 KEZ43753.1 - 5.2e-60 201.3 0.2 1.2e-59 200.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 KEZ43753.1 - 7.2e-45 152.9 0.0 1.9e-44 151.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEZ43753.1 - 6.9e-34 116.7 2.3 6.6e-29 100.5 0.3 2.7 1 1 1 2 2 2 2 DEAD_2 DEAD PF00270.24 KEZ43753.1 - 1.1e-05 24.9 0.0 3.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KEZ43753.1 - 0.00061 18.6 0.0 0.002 16.9 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 KEZ43753.1 - 0.017 14.3 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 KEZ43753.1 - 0.025 14.3 0.1 0.17 11.6 0.1 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEZ43753.1 - 0.04 14.0 0.3 0.88 9.7 0.2 2.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ43753.1 - 0.18 10.7 0.0 0.69 8.8 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2163 PF09931.4 KEZ43755.1 - 0.058 13.1 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) FAD_binding_3 PF01494.14 KEZ43757.1 - 2.3e-72 244.0 0.0 3e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEZ43757.1 - 4.2e-41 140.3 0.0 7.9e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KEZ43757.1 - 6.1e-06 26.5 0.0 0.0007 19.9 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ43757.1 - 0.0025 17.7 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ43757.1 - 0.0046 15.9 0.0 0.0086 15.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ43757.1 - 0.0077 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEZ43757.1 - 0.011 14.2 0.0 0.02 13.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KEZ43757.1 - 0.015 14.2 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ43757.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.1 KEZ43757.1 - 0.039 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 KEZ43757.1 - 0.095 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 ThiF family SE PF08491.5 KEZ43757.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Peptidase_C48 PF02902.14 KEZ43758.1 - 4.5e-19 68.9 0.0 9.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1682 PF07946.9 KEZ43758.1 - 0.0018 17.2 5.8 0.0031 16.4 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RGS PF00615.14 KEZ43759.1 - 1.5e-11 44.4 0.0 2.3e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain LigB PF02900.13 KEZ43760.1 - 5.8e-39 133.7 0.0 6.4e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DAO PF01266.19 KEZ43761.1 - 6.7e-53 179.8 0.0 9.4e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ43761.1 - 1e-08 34.4 0.0 2.4e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KEZ43761.1 - 2.1e-07 30.3 0.1 1.1e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ43761.1 - 0.00023 21.0 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ43761.1 - 0.0023 17.8 0.1 0.0083 16.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEZ43761.1 - 0.0083 15.0 0.1 0.036 12.9 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KEZ43761.1 - 0.0084 15.0 0.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KEZ43761.1 - 0.0098 16.2 0.2 0.029 14.7 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ43761.1 - 0.012 14.1 0.2 0.018 13.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KEZ43761.1 - 0.019 14.6 0.1 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KEZ43761.1 - 0.029 13.4 0.2 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 KEZ43761.1 - 0.06 12.3 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain PTH2 PF01981.11 KEZ43762.1 - 8.6e-47 157.6 0.2 1.1e-46 157.2 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Hom_end PF05204.9 KEZ43762.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Homing endonuclease cobW PF02492.14 KEZ43763.1 - 3e-35 121.2 0.0 3.6e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KEZ43763.1 - 4.3e-05 22.4 0.9 0.00079 18.2 0.6 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 KEZ43763.1 - 0.015 15.2 0.0 0.039 13.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KEZ43763.1 - 0.016 15.5 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEZ43763.1 - 0.082 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 KEZ43763.1 - 0.095 12.0 1.0 0.19 11.1 0.7 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KEZ43763.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 KEZ43763.1 - 0.12 13.2 0.2 0.26 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain BING4CT PF08149.6 KEZ43764.1 - 1.3e-39 133.5 0.0 5.9e-37 125.0 0.0 3.1 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 KEZ43764.1 - 3.4e-06 26.7 0.0 0.0014 18.4 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KEZ43764.1 - 0.00016 20.6 0.3 0.0006 18.7 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region SNAP PF14938.1 KEZ43765.1 - 7.7e-108 359.9 12.5 1.1e-107 359.4 8.7 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KEZ43765.1 - 2.6e-07 30.4 11.7 0.004 17.0 2.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ43765.1 - 0.00018 21.0 5.6 0.047 13.5 0.2 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ43765.1 - 0.00042 20.0 15.2 1.1 9.3 0.4 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ43765.1 - 0.00051 19.6 13.3 0.046 13.3 3.2 3.5 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.1 KEZ43765.1 - 0.027 14.2 11.4 0.097 12.4 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ43765.1 - 0.031 14.7 12.1 34 5.2 0.0 5.8 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF2521 PF10730.4 KEZ43765.1 - 0.036 13.9 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) TPR_1 PF00515.23 KEZ43765.1 - 0.041 13.5 13.0 2.1 8.1 0.2 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat NSF PF02071.15 KEZ43765.1 - 7.4 7.6 17.0 27 5.9 0.1 5.4 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat DUF726 PF05277.7 KEZ43766.1 - 9.6e-77 258.1 0.0 1.4e-76 257.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PPI_Ypi1 PF07491.6 KEZ43767.1 - 6.6e-24 83.3 6.3 3.2e-23 81.1 4.4 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.4 KEZ43767.1 - 0.00044 19.7 7.2 0.00062 19.2 5.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 KEZ43767.1 - 0.1 10.6 8.5 0.12 10.3 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.9 KEZ43767.1 - 5.8 6.2 8.7 8.8 5.6 6.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 KEZ43767.1 - 7.8 5.3 8.1 9.2 5.1 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.6 KEZ43767.1 - 8.1 6.2 7.7 13 5.6 5.4 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DENN PF02141.16 KEZ43768.1 - 3e-55 186.8 0.0 5.5e-55 185.9 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 KEZ43768.1 - 6.8e-19 67.6 0.5 1.3e-18 66.7 0.3 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 KEZ43768.1 - 3e-16 59.1 0.0 6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 uDENN domain PHD PF00628.24 KEZ43768.1 - 0.18 11.5 5.7 0.2 11.3 2.3 2.2 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.17 KEZ43768.1 - 0.44 10.3 8.0 0.98 9.1 5.1 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 KEZ43768.1 - 3.2 7.9 7.9 0.67 10.1 2.6 2.0 2 0 0 2 2 2 0 C1 domain MMR_HSR1 PF01926.18 KEZ43769.1 - 2.2e-05 24.3 0.0 7.7e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1127 PF06568.6 KEZ43769.1 - 0.14 11.6 0.3 0.4 10.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) L51_S25_CI-B8 PF05047.11 KEZ43770.1 - 2.5e-13 49.5 0.1 3.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HBS1_N PF08938.5 KEZ43770.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 HBS1 N-terminus HECT PF00632.20 KEZ43771.1 - 1e-60 205.5 0.0 1.1e-34 120.0 0.0 2.2 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) OrfB_Zn_ribbon PF07282.6 KEZ43771.1 - 0.039 13.6 0.7 0.1 12.2 0.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_1 PF00130.17 KEZ43771.1 - 0.062 13.0 1.0 0.14 11.9 0.7 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_pol_Rpc82 PF05645.8 KEZ43771.1 - 0.24 10.9 2.8 0.46 9.9 1.9 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 S10_plectin PF03501.10 KEZ43772.1 - 4.7e-41 138.5 0.1 5.6e-41 138.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain COX6B PF02297.12 KEZ43773.1 - 1.6e-19 69.6 5.9 1.9e-19 69.4 4.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 KEZ43773.1 - 0.013 14.8 2.0 0.016 14.6 1.2 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain CHCH PF06747.8 KEZ43773.1 - 0.039 13.8 0.7 0.1 12.5 0.5 1.8 1 1 0 1 1 1 0 CHCH domain ketoacyl-synt PF00109.21 KEZ43773.1 - 0.064 12.7 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCR_hinge PF02320.11 KEZ43773.1 - 0.074 12.9 0.7 0.11 12.4 0.4 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein B12D PF06522.6 KEZ43774.1 - 3.5e-06 26.6 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 KEZ43775.1 - 1.2e-18 66.5 0.0 1.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ43775.1 - 3e-15 55.9 0.0 4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ43775.1 - 5.7e-11 42.1 0.0 7.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ43775.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEZ43775.1 - 0.043 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Gemini_BL1 PF00845.14 KEZ43775.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Geminivirus BL1 movement protein WD40 PF00400.27 KEZ43776.1 - 2.3e-20 71.6 1.3 4.3e-06 26.4 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat SRA1 PF07304.6 KEZ43776.1 - 2.8e-11 43.3 0.0 2.8e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KEZ43776.1 - 4.7e-07 29.8 0.1 9.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Pkinase PF00069.20 KEZ43777.1 - 4.5e-19 68.6 0.0 6.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43777.1 - 2.3e-08 33.4 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ43777.1 - 0.0089 15.7 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family PfkB PF00294.19 KEZ43778.1 - 7.1e-12 45.0 0.0 8.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TPR_2 PF07719.12 KEZ43779.1 - 3.4e-14 51.5 2.9 6e-05 22.6 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ43779.1 - 6.8e-13 47.6 0.2 4.3e-06 26.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ43779.1 - 2.9e-09 36.4 4.8 7.2e-06 25.5 0.0 2.8 1 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 KEZ43779.1 - 7.3e-09 34.7 0.9 0.022 14.5 0.4 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ43779.1 - 9.7e-08 32.4 1.4 0.037 14.7 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ43779.1 - 1.6e-07 31.1 2.4 0.029 14.3 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ43779.1 - 1.7e-07 31.2 8.1 0.00091 19.6 0.1 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ43779.1 - 8.9e-05 22.2 0.6 0.00037 20.2 0.4 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ43779.1 - 0.0053 17.0 2.8 0.057 13.7 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ43779.1 - 0.0061 16.9 4.4 6.3 7.4 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ43779.1 - 0.0071 16.4 4.4 13 6.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ43779.1 - 0.023 14.6 2.9 12 5.9 0.1 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 KEZ43779.1 - 0.044 14.4 0.4 26 5.6 0.2 3.2 3 0 0 3 3 3 0 Sel1 repeat TPR_7 PF13176.1 KEZ43779.1 - 0.045 13.5 9.1 1.3 8.9 0.1 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat SNAP PF14938.1 KEZ43779.1 - 0.073 12.2 3.4 0.11 11.5 1.6 1.8 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 KEZ43779.1 - 0.075 13.1 1.2 0.34 11.0 0.7 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 IBR PF01485.16 KEZ43779.1 - 0.099 12.5 0.3 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 IBR domain GET2 PF08690.5 KEZ43780.1 - 9.6e-12 44.7 0.4 2.6e-10 40.0 0.0 2.5 2 1 0 2 2 2 1 GET complex subunit GET2 HLH PF00010.21 KEZ43782.1 - 9.6e-07 28.4 0.0 1.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_DNAp_acc PF04929.7 KEZ43782.1 - 1 8.2 5.1 1.5 7.6 3.5 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Gp_dh_C PF02800.15 KEZ43783.1 - 2.4e-74 247.9 0.1 3.8e-74 247.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KEZ43783.1 - 3.4e-60 202.3 0.4 6.2e-60 201.5 0.3 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KEZ43783.1 - 0.0025 17.7 0.2 0.0088 15.9 0.1 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KEZ43783.1 - 0.043 12.9 0.2 0.1 11.7 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UFD1 PF03152.9 KEZ43785.1 - 4.4e-66 221.3 0.0 5.8e-66 220.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TIP49 PF06068.8 KEZ43787.1 - 3.6e-172 572.5 2.7 4.3e-172 572.3 1.9 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KEZ43787.1 - 1.2e-10 40.8 2.0 5.6e-07 28.8 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KEZ43787.1 - 7.8e-09 35.8 2.8 7.3e-06 26.2 0.0 3.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KEZ43787.1 - 1.5e-06 27.3 1.3 1.7e-06 27.1 0.2 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 KEZ43787.1 - 1.8e-06 28.0 0.0 2.3e-05 24.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ43787.1 - 4.7e-05 23.5 0.0 0.08 13.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KEZ43787.1 - 0.00029 20.0 0.9 0.0051 16.0 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEZ43787.1 - 0.00033 20.3 0.1 0.054 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEZ43787.1 - 0.00055 19.4 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEZ43787.1 - 0.0015 18.4 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEZ43787.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 KEZ43787.1 - 0.0062 16.1 0.1 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KEZ43787.1 - 0.008 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ43787.1 - 0.0091 15.8 0.0 0.039 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KEZ43787.1 - 0.011 15.1 0.0 4.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 KEZ43787.1 - 0.035 14.4 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KEZ43787.1 - 0.046 13.1 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KEZ43787.1 - 0.072 12.1 0.3 0.17 10.9 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin DNA_pol3_delta PF06144.8 KEZ43787.1 - 0.093 12.2 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Parvo_NS1 PF01057.12 KEZ43787.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Reo_sigmaC PF04582.7 KEZ43788.1 - 6.2e-08 32.1 33.0 0.001 18.2 1.2 5.2 1 1 4 5 5 5 4 Reovirus sigma C capsid protein Filament PF00038.16 KEZ43788.1 - 0.0021 17.5 5.9 0.0021 17.5 4.1 5.2 2 2 0 4 4 4 2 Intermediate filament protein HALZ PF02183.13 KEZ43788.1 - 0.0062 16.2 1.0 0.0062 16.2 0.7 5.4 5 1 1 6 6 6 1 Homeobox associated leucine zipper DUF972 PF06156.8 KEZ43788.1 - 0.0082 16.4 7.2 0.0082 16.4 5.0 6.5 4 2 2 6 6 6 1 Protein of unknown function (DUF972) Hemerythrin PF01814.18 KEZ43788.1 - 0.019 15.1 14.6 0.2 11.8 0.0 6.4 2 1 3 5 5 5 0 Hemerythrin HHE cation binding domain TPR_MLP1_2 PF07926.7 KEZ43788.1 - 0.045 13.4 0.1 0.045 13.4 0.1 5.2 4 3 0 5 5 4 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 KEZ43788.1 - 0.16 10.9 41.5 0.019 14.0 12.4 4.7 3 2 2 5 5 5 0 Autophagy protein Apg6 IncA PF04156.9 KEZ43788.1 - 0.27 10.7 43.4 1.2 8.6 1.3 5.3 2 2 4 6 6 6 0 IncA protein Syntaxin-6_N PF09177.6 KEZ43788.1 - 0.34 11.3 37.0 3.6 8.0 0.8 8.0 4 1 3 7 7 7 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KEZ43788.1 - 0.81 9.6 24.3 1 9.3 0.1 6.7 7 1 1 8 8 7 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 KEZ43788.1 - 1.4 8.4 52.5 0.83 9.1 7.4 7.6 5 2 2 8 8 8 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Seryl_tRNA_N PF02403.17 KEZ43788.1 - 2 8.4 42.5 4.1 7.4 2.4 7.7 6 2 2 8 8 8 0 Seryl-tRNA synthetase N-terminal domain CALCOCO1 PF07888.6 KEZ43788.1 - 3.2 5.9 36.5 0.49 8.6 5.2 3.7 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.1 KEZ43788.1 - 3.3 6.0 34.6 0.18 10.2 7.9 3.5 1 1 1 4 4 4 0 AAA domain Ycf1 PF05758.7 KEZ43788.1 - 3.8 5.0 10.3 0.25 8.9 3.6 1.5 2 0 0 2 2 2 0 Ycf1 Spc7 PF08317.6 KEZ43788.1 - 5.6 5.5 46.1 1.1 7.8 6.3 5.3 3 2 3 6 6 6 0 Spc7 kinetochore protein RTBV_P46 PF06216.6 KEZ43788.1 - 7.8 5.2 7.0 24 3.6 0.0 3.0 3 0 0 3 3 3 0 Rice tungro bacilliform virus P46 protein FlxA PF14282.1 KEZ43788.1 - 9.2 6.2 48.7 1.5 8.8 10.1 6.8 5 1 1 6 6 6 0 FlxA-like protein MAD PF05557.8 KEZ43788.1 - 9.3 4.1 46.7 0.59 8.1 4.2 4.5 3 1 1 4 4 4 0 Mitotic checkpoint protein LacI PF00356.16 KEZ43789.1 - 0.028 14.0 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family IER PF05760.7 KEZ43789.1 - 0.35 10.7 3.0 0.96 9.3 2.1 1.8 1 1 0 1 1 1 0 Immediate early response protein (IER) Med15 PF09606.5 KEZ43790.1 - 0.011 14.0 62.0 0.013 13.7 43.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 KEZ43790.1 - 0.13 10.4 67.7 0.16 10.1 46.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM222A PF15258.1 KEZ43790.1 - 2.3 7.3 37.3 3.1 6.9 25.8 1.1 1 0 0 1 1 1 0 Protein family of FAM222A DUF106 PF01956.11 KEZ43790.1 - 5.5 6.4 9.0 8.3 5.9 6.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 XRCC4 PF06632.7 KEZ43793.1 - 6.1e-05 22.0 25.1 0.0014 17.6 17.4 2.0 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Arc_PepC PF06819.6 KEZ43793.1 - 0.042 13.7 0.3 0.081 12.8 0.2 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain DUF3585 PF12130.3 KEZ43793.1 - 0.053 13.3 5.6 0.11 12.3 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Use1 PF09753.4 KEZ43793.1 - 0.73 9.2 8.3 1.4 8.3 5.7 1.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 CN_hydrolase PF00795.17 KEZ43795.1 - 2.5e-10 40.0 0.0 4.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cofilin_ADF PF00241.15 KEZ43796.1 - 7.1e-34 116.4 0.8 8.3e-34 116.2 0.6 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.8 KEZ43796.1 - 0.031 12.6 0.1 0.043 12.1 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein Acetyltransf_2 PF00797.12 KEZ43796.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.0 1 0 0 1 1 1 0 N-acetyltransferase Blt1 PF12754.2 KEZ43797.1 - 1.3e-31 110.3 5.3 2e-25 90.0 0.6 2.2 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 KEZ43797.1 - 0.00019 20.7 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Cpn60_TCP1 PF00118.19 KEZ43798.1 - 1.9e-119 399.4 8.5 2.2e-119 399.2 5.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 KEZ43798.1 - 0.25 11.0 1.8 0.56 9.9 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Ribonuclease_3 PF00636.21 KEZ43801.1 - 7e-10 39.3 0.1 2.9e-09 37.3 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEZ43801.1 - 4.5e-07 29.8 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KEZ43801.1 - 0.0019 18.7 0.0 0.004 17.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif TPR_12 PF13424.1 KEZ43802.1 - 2.5e-34 117.0 9.1 4.1e-11 42.6 0.3 5.4 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ43802.1 - 4.7e-25 86.7 17.7 0.00011 22.0 0.1 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ43802.1 - 6e-08 33.1 8.7 0.061 14.0 0.1 5.4 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ43802.1 - 1.5e-07 31.6 10.1 0.0024 18.1 0.1 4.8 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ43802.1 - 2.9e-07 30.0 1.2 5.1 6.8 0.2 5.3 4 1 2 6 6 6 2 TPR repeat TPR_14 PF13428.1 KEZ43802.1 - 4.8e-06 26.7 11.1 1.2 9.9 0.0 6.6 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ43802.1 - 9.9e-06 25.5 24.7 0.083 13.3 0.2 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ43802.1 - 1e-05 25.0 17.0 0.38 10.7 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KEZ43802.1 - 0.00065 19.7 0.1 5.5 7.2 0.0 4.2 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 KEZ43802.1 - 0.0013 18.8 0.0 0.041 14.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain TPR_8 PF13181.1 KEZ43802.1 - 0.0017 17.9 2.4 13 5.8 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ43802.1 - 0.0026 17.2 8.9 5.8 6.7 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 KEZ43802.1 - 0.0094 15.8 0.1 0.33 10.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ43802.1 - 0.0095 15.6 7.5 9.9 6.2 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat KaiC PF06745.8 KEZ43802.1 - 0.014 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 KEZ43802.1 - 0.079 11.8 0.0 0.8 8.5 0.0 2.2 1 1 0 1 1 1 0 NB-ARC domain TPR_17 PF13431.1 KEZ43802.1 - 0.16 12.2 6.7 15 6.1 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 KEZ43802.1 - 0.22 11.5 1.7 11 6.2 0.0 4.4 5 0 0 5 5 4 0 PPR repeat TPR_6 PF13174.1 KEZ43802.1 - 1.3 9.5 8.7 2e+02 2.7 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat p450 PF00067.17 KEZ43803.1 - 2.6e-57 194.3 0.0 4e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ACBP PF00887.14 KEZ43804.1 - 5.6e-30 102.8 0.0 1.5e-29 101.4 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2628 PF10947.3 KEZ43804.1 - 0.00057 19.6 0.5 0.00096 18.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) Opi1 PF08618.5 KEZ43804.1 - 0.014 14.3 2.8 0.017 14.0 2.0 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 Phyto_Pns9_10 PF05878.6 KEZ43804.1 - 0.014 14.4 0.7 0.019 13.9 0.5 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 NTPase_P4 PF11602.3 KEZ43804.1 - 0.035 13.1 0.2 0.052 12.5 0.2 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 DUF2347 PF09804.4 KEZ43804.1 - 0.17 11.1 0.7 0.23 10.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) RP-C_C PF11800.3 KEZ43804.1 - 0.2 11.3 4.5 0.067 12.8 1.3 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region Molybdopterin PF00384.17 KEZ43806.1 - 2.8e-67 227.3 0.0 2.6e-65 220.8 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KEZ43806.1 - 3.1e-19 68.5 0.3 9.1e-19 67.0 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KEZ43806.1 - 5.1e-19 67.2 0.1 1.3e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KEZ43806.1 - 1.5e-14 53.8 0.0 4.3e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KEZ43806.1 - 4.8e-08 32.6 0.6 4.8e-08 32.6 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KEZ43806.1 - 0.038 13.7 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Aldo_ket_red PF00248.16 KEZ43807.1 - 3.2e-44 150.8 0.0 4.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 KEZ43807.1 - 1.3e-23 83.6 0.0 2.1e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2375 PF09558.5 KEZ43807.1 - 0.098 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) MRP-S33 PF08293.6 KEZ43808.1 - 2.7e-27 94.5 0.1 3.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.14 KEZ43809.1 - 9.8e-39 128.6 0.7 3.4e-06 26.2 0.0 8.7 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat PP2C PF00481.16 KEZ43811.1 - 1.1e-39 136.3 0.0 1.9e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KEZ43811.1 - 0.0013 18.4 0.0 0.12 12.0 0.0 3.0 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) SLAC1 PF03595.12 KEZ43812.1 - 3.3e-69 233.0 45.6 3.8e-69 232.8 31.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Ribosomal_S5_C PF03719.10 KEZ43813.1 - 7.1e-18 63.6 0.2 3.9e-17 61.2 0.0 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KEZ43813.1 - 3.3e-09 36.3 0.9 7.9e-09 35.1 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 KEZ43814.1 - 3.2e-28 97.2 0.1 3.7e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 PSP1 PF04468.7 KEZ43815.1 - 1.1e-30 105.4 0.5 2.1e-30 104.5 0.4 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region HlyD PF00529.15 KEZ43815.1 - 0.0047 16.2 1.4 0.0082 15.4 1.0 1.3 1 0 0 1 1 1 1 HlyD family secretion protein Rotavirus_VP3 PF06929.6 KEZ43815.1 - 0.38 8.5 0.5 0.56 8.0 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Ribosomal_L15e PF00827.12 KEZ43818.1 - 1.2e-90 302.1 10.5 1.4e-90 302.0 7.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.14 KEZ43819.1 - 7.2e-60 195.2 10.3 1.3e-07 30.7 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 KEZ43819.1 - 0.032 13.3 0.1 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DUF445 PF04286.7 KEZ43819.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RNA_pol_Rpb2_6 PF00562.23 KEZ43820.1 - 5.4e-116 387.5 0.2 1e-115 386.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KEZ43820.1 - 5.8e-51 172.3 0.1 1e-50 171.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KEZ43820.1 - 3.4e-31 108.1 0.2 1.1e-30 106.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KEZ43820.1 - 2.1e-29 101.6 0.2 7.1e-29 99.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KEZ43820.1 - 7.3e-21 73.7 0.2 1.7e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KEZ43820.1 - 3.1e-20 71.6 0.0 6.4e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KEZ43820.1 - 3.8e-12 45.9 0.3 9.9e-12 44.6 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 KEZ43820.1 - 0.081 11.2 0.1 0.14 10.4 0.1 1.3 1 0 0 1 1 1 0 Baculovirus Y142 protein AAA PF00004.24 KEZ43821.1 - 4.1e-15 56.1 0.0 7.3e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ43821.1 - 0.012 15.5 0.6 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KEZ43821.1 - 0.022 14.8 0.2 0.081 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEZ43821.1 - 0.11 13.3 4.9 0.19 12.5 0.0 3.6 3 1 0 3 3 3 0 AAA domain DUF1191 PF06697.7 KEZ43822.1 - 0.0054 15.5 0.1 0.015 14.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 KEZ43822.1 - 0.053 13.1 0.2 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 KEZ43822.1 - 0.073 12.3 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PDGLE PF13190.1 KEZ43822.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 PDGLE domain Carn_acyltransf PF00755.15 KEZ43823.1 - 4.1e-160 533.7 0.0 8.8e-145 483.1 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase MFS_1 PF07690.11 KEZ43824.1 - 1.4e-33 116.0 52.3 3.3e-33 114.8 34.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43824.1 - 1.3e-09 37.1 13.1 1.3e-09 37.1 9.1 3.3 2 2 2 4 4 4 1 Sugar (and other) transporter MFS_2 PF13347.1 KEZ43824.1 - 3.5e-06 25.7 26.7 0.00036 19.0 3.2 3.7 1 1 1 2 2 2 2 MFS/sugar transport protein TcdA_TcdB_pore PF12920.2 KEZ43824.1 - 0.55 8.0 1.1 0.88 7.4 0.7 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF4535 PF15054.1 KEZ43824.1 - 1.3 8.5 6.3 10 5.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) PET122 PF05476.6 KEZ43826.1 - 0.0024 17.1 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 PET122 Pkinase PF00069.20 KEZ43827.1 - 1.8e-71 240.3 0.0 5.3e-71 238.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43827.1 - 4.2e-30 104.6 0.0 5.7e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEZ43827.1 - 9.1e-06 24.8 0.0 0.4 9.5 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KEZ43827.1 - 0.043 12.8 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.19 KEZ43828.1 - 4.2e-05 23.1 0.9 4.2e-05 23.1 0.6 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEZ43828.1 - 1.3 9.1 7.1 6.4 6.9 0.1 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type CS PF04969.11 KEZ43829.1 - 1.4e-10 41.6 0.5 2.3e-10 40.8 0.4 1.4 1 1 0 1 1 1 1 CS domain DUF1958 PF09211.5 KEZ43829.1 - 0.2 11.7 2.2 0.19 11.8 0.3 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1958) CorA PF01544.13 KEZ43830.1 - 0.0074 15.3 3.4 0.013 14.5 2.3 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Snf7 PF03357.16 KEZ43831.1 - 4.3e-21 75.0 5.9 4.3e-21 75.0 4.1 1.6 2 0 0 2 2 2 1 Snf7 IF-2 PF11987.3 KEZ43831.1 - 0.00074 19.3 0.7 0.44 10.4 0.1 2.5 2 0 0 2 2 2 2 Translation-initiation factor 2 Hydrolase_like PF13242.1 KEZ43832.1 - 1.9e-07 30.7 0.0 3.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KEZ43832.1 - 1.8e-05 25.0 0.0 0.14 12.3 0.1 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase NACHT PF05729.7 KEZ43833.1 - 2.5e-05 23.9 0.9 0.00014 21.5 0.6 2.2 1 1 0 1 1 1 1 NACHT domain Ank_2 PF12796.2 KEZ43833.1 - 0.0004 20.6 0.0 0.016 15.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43833.1 - 0.062 13.1 0.0 33 4.5 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat SNF2_N PF00176.18 KEZ43834.1 - 4.9e-32 110.9 0.0 8.9e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ43834.1 - 1.4e-11 44.1 0.0 2.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KEZ43834.1 - 0.0001 21.9 4.3 0.0001 21.9 3.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ43834.1 - 0.0039 17.0 5.0 0.0039 17.0 3.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KEZ43834.1 - 0.015 14.9 3.3 0.015 14.9 2.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ43834.1 - 6 6.9 11.7 0.22 11.5 3.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.17 KEZ43836.1 - 1.3e-17 63.6 0.0 1.9e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ43836.1 - 7.6e-08 32.8 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ43836.1 - 0.052 12.7 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family PduV-EutP PF10662.4 KEZ43836.1 - 0.067 12.6 0.0 0.19 11.2 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb4 PF03874.11 KEZ43837.1 - 2e-22 79.3 0.1 2.4e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 HTH_32 PF13565.1 KEZ43837.1 - 0.017 15.9 0.0 0.033 14.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain TerB PF05099.8 KEZ43837.1 - 0.064 12.9 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TerB COG6 PF06419.6 KEZ43837.1 - 0.075 11.1 0.1 0.087 10.9 0.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Pribosyl_synth PF14572.1 KEZ43838.1 - 1e-43 149.2 1.0 1.5e-38 132.4 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KEZ43838.1 - 4.1e-31 107.1 0.0 1.4e-30 105.4 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KEZ43838.1 - 1.9e-12 47.0 0.2 4.8e-12 45.6 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KEZ43838.1 - 0.0043 16.2 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_63 PF03200.11 KEZ43839.1 - 1.2e-08 33.3 5.6 3e-07 28.7 0.1 3.6 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase RasGEF PF00617.14 KEZ43840.1 - 6.9e-46 156.3 0.2 1.2e-45 155.5 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 KEZ43840.1 - 8.8e-13 48.8 0.0 9.6e-12 45.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein RasGEF_N PF00618.15 KEZ43840.1 - 1.4e-12 47.5 0.2 6.7e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.17 KEZ43840.1 - 0.0054 16.1 0.0 0.56 9.5 0.0 2.8 2 1 0 2 2 2 1 Ras family DUF815 PF05673.8 KEZ43840.1 - 0.026 13.4 0.0 0.057 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 KEZ43840.1 - 0.036 14.0 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 KEZ43840.1 - 0.19 11.6 0.0 0.72 9.8 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-HIT PF04438.11 KEZ43841.1 - 8.8e-10 38.0 10.6 1.2e-09 37.5 7.3 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KEZ43841.1 - 0.00014 21.6 5.9 0.00022 21.0 4.1 1.3 1 0 0 1 1 1 1 MYND finger zf-Apc11 PF12861.2 KEZ43841.1 - 0.15 11.9 2.0 0.23 11.3 1.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Nfu_N PF08712.6 KEZ43842.1 - 8.1e-27 92.6 0.0 2.6e-26 91.0 0.0 1.9 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KEZ43842.1 - 4.7e-22 77.5 0.0 1.1e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 NifU-like domain Glyco_hyd_65N_2 PF14498.1 KEZ43843.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain LSM PF01423.17 KEZ43844.1 - 1.1e-12 47.3 0.0 1.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain NUDIX PF00293.23 KEZ43845.1 - 1.3e-17 63.7 0.6 1.6e-17 63.3 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 KEZ43845.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase ATE_C PF04377.10 KEZ43846.1 - 1.8e-42 144.3 0.1 2.9e-42 143.7 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KEZ43846.1 - 2.7e-14 52.7 1.9 3.5e-14 52.3 0.4 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Ribosomal_60s PF00428.14 KEZ43846.1 - 0.0011 19.3 5.7 0.0021 18.4 4.0 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein OSCP PF00213.13 KEZ43847.1 - 1.8e-45 154.8 0.6 2.3e-45 154.5 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.12 KEZ43848.1 - 1.7e-69 232.9 0.0 2.1e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Peptidase_M41 PF01434.13 KEZ43850.1 - 2.2e-62 210.3 0.3 3.3e-62 209.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KEZ43850.1 - 1.1e-42 145.3 0.0 4.1e-42 143.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ43850.1 - 1e-06 28.5 0.0 3.3e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KEZ43850.1 - 3.8e-05 24.5 0.0 0.00011 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEZ43850.1 - 4.1e-05 23.7 0.2 0.0046 17.1 0.1 3.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 KEZ43850.1 - 6.8e-05 21.7 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KEZ43850.1 - 0.0002 20.5 0.0 0.00056 19.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KEZ43850.1 - 0.0004 19.8 2.1 0.081 12.3 0.3 2.9 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 KEZ43850.1 - 0.00051 20.0 3.6 0.0047 16.9 0.3 3.3 3 1 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 KEZ43850.1 - 0.0016 18.3 0.0 0.0062 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ43850.1 - 0.0031 17.2 1.6 0.016 14.9 1.1 2.2 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KEZ43850.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KEZ43850.1 - 0.0055 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEZ43850.1 - 0.0066 15.5 1.6 0.025 13.6 0.2 2.3 1 1 1 2 2 2 1 Zeta toxin DUF815 PF05673.8 KEZ43850.1 - 0.0091 14.9 0.0 0.036 12.9 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KEZ43850.1 - 0.02 14.0 0.2 0.04 13.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KEZ43850.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KEZ43850.1 - 0.07 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) KaiC PF06745.8 KEZ43850.1 - 0.094 11.8 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 KEZ43850.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEZ43850.1 - 0.14 11.3 0.2 0.31 10.2 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-H2C2_2 PF13465.1 KEZ43851.1 - 9.9e-21 72.9 25.8 7.7e-08 32.2 0.3 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ43851.1 - 1.3e-19 69.2 30.2 1.8e-05 24.8 1.3 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ43851.1 - 1.5e-09 37.5 25.9 0.00055 20.0 1.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ43851.1 - 0.00032 20.7 5.4 1.6 8.9 0.4 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KEZ43851.1 - 0.012 15.9 14.2 0.073 13.4 1.6 3.2 1 1 2 3 3 3 0 TRAF-type zinc finger zf-met PF12874.2 KEZ43851.1 - 0.022 14.9 11.8 0.025 14.7 0.7 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KEZ43851.1 - 0.75 9.5 5.1 34 4.2 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type CHORD PF04968.7 KEZ43851.1 - 6.6 7.0 15.2 9.6 6.5 0.1 4.2 1 1 3 4 4 4 0 CHORD GDPD PF03009.12 KEZ43852.1 - 2.7e-62 210.5 0.0 1.4e-61 208.2 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KEZ43852.1 - 4e-29 100.7 0.9 1.3e-12 47.8 0.1 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ43852.1 - 3.7e-27 94.2 0.3 2e-09 37.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) SPX PF03105.14 KEZ43852.1 - 1.3e-25 90.7 17.9 6.8e-16 58.8 2.5 3.9 4 1 0 4 4 4 2 SPX domain Ank PF00023.25 KEZ43852.1 - 1.2e-23 81.6 6.4 3.3e-07 29.7 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 KEZ43852.1 - 3.4e-22 77.9 0.1 2.3e-07 30.8 0.0 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43852.1 - 1.4e-16 58.8 1.7 8.2e-05 22.4 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat DUF866 PF05907.8 KEZ43853.1 - 3.9e-34 117.4 1.1 4.2e-32 110.8 0.2 2.8 2 1 1 3 3 3 1 Eukaryotic protein of unknown function (DUF866) Rpr2 PF04032.11 KEZ43853.1 - 6.7e-11 41.9 2.3 1.9e-09 37.2 0.6 2.9 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.7 KEZ43853.1 - 0.039 13.2 2.1 31 3.9 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.5 KEZ43853.1 - 0.047 13.6 1.6 21 5.1 0.0 3.5 3 0 0 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.9 KEZ43853.1 - 0.061 12.9 2.2 4.2 7.1 0.0 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid DUF951 PF06107.6 KEZ43853.1 - 0.074 12.5 0.4 2.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) Pox_P4B PF03292.9 KEZ43853.1 - 0.13 10.1 2.3 0.069 11.0 0.4 1.4 1 1 1 2 2 2 0 Poxvirus P4B major core protein FYVE PF01363.16 KEZ43853.1 - 0.14 12.0 4.6 0.69 9.8 0.8 2.8 2 1 0 2 2 2 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 KEZ43853.1 - 0.24 11.2 3.7 8.1 6.3 0.1 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 KEZ43853.1 - 1.1 8.9 7.8 0.95 9.2 0.3 3.2 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KEZ43853.1 - 1.3 8.6 7.6 1.3 8.7 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-ZPR1 PF03367.8 KEZ43854.1 - 3.1e-101 335.2 0.0 1.2e-50 170.7 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 KEZ43854.1 - 0.041 13.5 2.5 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KEZ43854.1 - 0.46 10.4 6.6 7.4 6.6 0.1 4.1 4 0 0 4 4 4 0 Zinc ribbon domain UPF0547 PF10571.4 KEZ43854.1 - 0.92 9.2 6.4 1.7 8.3 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Lar_restr_allev PF14354.1 KEZ43854.1 - 1.4 9.2 5.3 18 5.7 0.8 3.0 3 0 0 3 3 3 0 Restriction alleviation protein Lar TAF4 PF05236.9 KEZ43854.1 - 2.3 7.3 4.8 3.7 6.7 3.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Elf1 PF05129.8 KEZ43854.1 - 2.5 7.8 5.8 7.6 6.3 0.2 2.6 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like SKG6 PF08693.5 KEZ43855.1 - 0.011 15.0 0.8 0.011 15.0 0.6 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.20 KEZ43856.1 - 3.5e-38 131.2 0.0 4.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43856.1 - 1.8e-15 56.7 0.0 2.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ43856.1 - 0.0013 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ43856.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyclin_N PF00134.18 KEZ43857.1 - 0.0074 15.8 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 KEZ43857.1 - 0.044 14.1 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin Ribonuclease_3 PF00636.21 KEZ43859.1 - 9.3e-43 145.2 0.0 1.1e-21 77.4 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEZ43859.1 - 3.2e-28 98.2 0.0 5.6e-12 45.7 0.0 3.8 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KEZ43859.1 - 3.4e-16 58.7 0.1 1.7e-14 53.3 0.1 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 KEZ43859.1 - 1.1e-14 54.7 0.1 2.4e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEZ43859.1 - 2.4e-14 52.9 0.0 7.3e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ43859.1 - 7.4e-10 38.5 0.0 1.8e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KEZ43859.1 - 0.00033 19.5 0.8 0.00064 18.6 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KEZ43859.1 - 0.0067 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain dsrm PF00035.20 KEZ43859.1 - 0.072 13.6 0.3 27 5.4 0.0 3.3 3 0 0 3 3 3 0 Double-stranded RNA binding motif Peptidase_C12 PF01088.16 KEZ43861.1 - 2.8e-60 203.1 0.0 3.3e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 KEZ43861.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Synaptobrevin PF00957.16 KEZ43862.1 - 2.4e-31 107.1 0.2 3.5e-31 106.6 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KEZ43862.1 - 7.2e-23 79.9 0.0 1.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec1 PF00995.18 KEZ43863.1 - 2.8e-134 448.8 0.0 3.2e-134 448.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.7 KEZ43863.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) PRKCSH-like PF12999.2 KEZ43864.1 - 0.15 11.6 1.1 0.23 11.0 0.8 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF2007 PF09413.5 KEZ43865.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) DUF4351 PF14261.1 KEZ43865.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Npa1 PF11707.3 KEZ43867.1 - 3e-72 243.4 0.0 1.6e-71 241.0 0.0 2.0 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal His_Phos_2 PF00328.17 KEZ43869.1 - 6.4e-52 176.9 0.0 7.6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Inositol_P PF00459.20 KEZ43871.1 - 3e-63 213.6 0.0 3.4e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 KEZ43872.1 - 6.7e-34 117.1 22.1 1.1e-28 100.0 9.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43872.1 - 1.9e-09 36.6 3.4 1.9e-09 36.6 2.4 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KEZ43872.1 - 0.00038 18.9 2.1 0.00038 18.9 1.5 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 KEZ43872.1 - 0.063 11.3 4.2 0.26 9.3 2.9 1.9 1 1 0 1 1 1 0 Transmembrane secretion effector DUF3806 PF12713.2 KEZ43872.1 - 0.15 11.5 0.0 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) DUF1801 PF08818.6 KEZ43873.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DU1801) DNA_topoisoIV PF00521.15 KEZ43874.1 - 1.3e-117 393.2 0.1 6.5e-117 390.9 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KEZ43874.1 - 1.7e-32 112.0 1.7 3.4e-32 111.0 1.2 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KEZ43874.1 - 4.9e-13 48.8 0.2 3.5e-12 46.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 KEZ43874.1 - 1.6e-09 37.4 0.0 3.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 KEZ43875.1 - 5.7e-41 139.9 4.1 7.3e-41 139.5 2.8 1.1 1 0 0 1 1 1 1 Reticulon DUF1043 PF06295.7 KEZ43875.1 - 0.023 14.3 0.5 0.8 9.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DUF2547 PF10818.3 KEZ43875.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) RabGAP-TBC PF00566.13 KEZ43876.1 - 4.4e-41 140.7 0.0 1.1e-40 139.4 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Prominin PF05478.6 KEZ43876.1 - 0.31 8.5 2.5 0.48 7.8 1.7 1.2 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 KEZ43876.1 - 0.36 10.6 1.7 0.9 9.3 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cornifin PF02389.10 KEZ43877.1 - 0.058 13.1 23.7 0.041 13.6 6.8 2.8 1 1 1 2 2 2 0 Cornifin (SPRR) family GCV_H PF01597.14 KEZ43878.1 - 7.4e-33 112.8 1.3 9e-33 112.5 0.9 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KEZ43878.1 - 0.017 14.7 0.2 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF2118 PF09891.4 KEZ43878.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Ras PF00071.17 KEZ43879.1 - 9.9e-32 109.5 0.1 1.2e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ43879.1 - 4e-21 75.7 0.1 2.2e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KEZ43879.1 - 1.1e-06 28.0 0.1 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ43879.1 - 4.7e-05 22.6 0.1 6.1e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEZ43879.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 KEZ43879.1 - 0.063 11.9 0.4 0.17 10.4 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit DLIC PF05783.6 KEZ43879.1 - 0.1 11.2 0.2 3.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TPT PF03151.11 KEZ43881.1 - 3.4e-27 94.9 18.6 3.4e-27 94.9 12.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEZ43881.1 - 0.0003 19.7 24.2 0.0029 16.5 16.8 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEZ43881.1 - 0.25 11.3 37.8 0.31 11.0 6.4 3.0 3 1 0 3 3 3 0 EamA-like transporter family Glyco_transf_17 PF04724.8 KEZ43882.1 - 3.7e-43 147.9 0.7 5e-43 147.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Dak1 PF02733.12 KEZ43883.1 - 2.2e-113 378.0 3.8 3.1e-113 377.6 2.6 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KEZ43883.1 - 6.6e-43 146.3 0.0 1.2e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.17 KEZ43884.1 - 2.4e-18 65.4 0.1 3.1e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain ECH_C PF13766.1 KEZ43885.1 - 1.5e-36 125.1 0.2 5.4e-36 123.3 0.2 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KEZ43885.1 - 7.7e-25 87.4 0.0 4.8e-24 84.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family GATA PF00320.22 KEZ43886.1 - 0.001 18.3 6.2 0.038 13.3 0.5 2.6 2 0 0 2 2 2 2 GATA zinc finger Pol_alpha_B_N PF08418.5 KEZ43887.1 - 6.6e-53 179.8 0.0 8.9e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KEZ43887.1 - 8e-37 126.5 0.1 1.2e-36 125.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B An_peroxidase PF03098.10 KEZ43891.1 - 4e-94 315.8 0.0 1.2e-91 307.7 0.0 2.4 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KEZ43891.1 - 4.9e-07 28.6 0.0 2.1e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 SAM_decarbox PF01536.11 KEZ43892.1 - 7.4e-85 284.5 0.0 3.8e-65 219.7 0.0 3.7 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase ParA PF10609.4 KEZ43893.1 - 8.4e-34 115.3 0.0 1.4e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KEZ43893.1 - 1e-16 60.9 0.0 1.6e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KEZ43893.1 - 7.9e-06 25.1 0.3 0.00019 20.5 0.3 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KEZ43893.1 - 1.4e-05 24.2 0.0 0.00046 19.3 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 KEZ43893.1 - 0.00084 19.2 0.1 0.0019 18.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEZ43893.1 - 0.0012 18.2 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 KEZ43893.1 - 0.031 13.6 0.1 0.055 12.8 0.0 1.4 2 0 0 2 2 2 0 YhjQ protein ArgK PF03308.11 KEZ43893.1 - 0.034 12.9 0.2 0.056 12.2 0.1 1.2 1 0 0 1 1 1 0 ArgK protein APS_kinase PF01583.15 KEZ43893.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 KEZ43893.1 - 0.092 11.9 0.2 0.19 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ank_2 PF12796.2 KEZ43894.1 - 5.7e-50 167.6 2.6 9.4e-13 48.3 0.1 5.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ43894.1 - 6.6e-39 131.6 4.3 1.4e-09 38.2 0.0 7.3 3 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ43894.1 - 1.4e-36 123.6 7.2 8.3e-08 32.2 0.0 5.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43894.1 - 1.2e-33 111.7 0.3 0.00022 21.1 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.25 KEZ43894.1 - 5.7e-33 111.0 7.2 0.00049 19.7 0.0 9.0 10 0 0 10 10 10 7 Ankyrin repeat NACHT PF05729.7 KEZ43894.1 - 5.8e-06 26.0 0.1 3.2e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ43894.1 - 0.00017 21.7 0.0 0.00062 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Death PF00531.17 KEZ43894.1 - 0.0097 15.6 1.3 37 4.1 0.0 4.8 4 0 0 4 4 4 0 Death domain KAP_NTPase PF07693.9 KEZ43894.1 - 0.016 14.1 1.0 0.73 8.7 0.1 2.3 1 1 1 2 2 2 0 KAP family P-loop domain SchA_CurD PF04486.7 KEZ43894.1 - 0.052 13.3 0.7 98 2.8 0.0 5.1 2 2 5 7 7 7 0 SchA/CurD like domain AAA_29 PF13555.1 KEZ43894.1 - 0.07 12.6 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KEZ43894.1 - 0.13 11.1 0.0 0.35 9.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF2196 PF09962.4 KEZ43894.1 - 0.5 10.1 3.4 26 4.7 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2196) APH PF01636.18 KEZ43895.1 - 1.4e-16 60.9 0.3 5.4e-14 52.5 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ43895.1 - 2.2e-07 30.6 0.2 3.6e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KEZ43895.1 - 1.1e-05 24.9 0.9 0.031 13.6 0.3 2.1 1 1 1 2 2 2 2 RIO1 family Fructosamin_kin PF03881.9 KEZ43895.1 - 0.00035 19.6 0.0 0.0012 17.8 0.0 1.8 2 0 0 2 2 2 1 Fructosamine kinase Pkinase_Tyr PF07714.12 KEZ43895.1 - 0.099 11.6 0.2 0.85 8.6 0.1 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KEZ43895.1 - 0.11 11.6 0.3 8.5 5.4 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.18 KEZ43896.1 - 1.8e-10 40.9 0.1 1.5e-09 37.9 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ43896.1 - 0.024 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NmrA PF05368.8 KEZ43897.1 - 2.1e-15 56.6 0.0 1.4e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ43897.1 - 1.4e-06 28.4 0.0 5.6e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KEZ43897.1 - 0.0059 16.5 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ43897.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 KEZ43897.1 - 0.037 13.4 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CobT_C PF11775.3 KEZ43897.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain PGM_PMM_II PF02879.11 KEZ43897.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II p450 PF00067.17 KEZ43898.1 - 2.8e-38 131.6 0.0 3.5e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KEZ43901.1 - 6.9e-19 68.1 0.0 1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ43901.1 - 6e-16 58.7 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ43901.1 - 5.3e-15 55.3 0.0 4.1e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEZ43901.1 - 1.4e-12 47.3 0.0 9.4e-12 44.5 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KEZ43901.1 - 2.1e-12 47.3 0.0 6.6e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ43901.1 - 1.3e-11 45.0 0.0 2.7e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ43901.1 - 2e-09 37.7 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ43901.1 - 4.3e-08 33.1 0.0 9.7e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ43901.1 - 4.1e-05 22.7 0.0 0.00011 21.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.21 KEZ43901.1 - 0.00017 21.1 0.2 0.0049 16.4 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase MetW PF07021.7 KEZ43901.1 - 0.0013 18.1 0.0 0.24 10.7 0.0 2.3 1 1 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.9 KEZ43901.1 - 0.0024 17.2 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 KEZ43901.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KEZ43901.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 KEZ43901.1 - 0.045 14.5 0.0 0.085 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KEZ43901.1 - 0.08 12.9 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 KEZ43901.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CAF1A PF12253.3 KEZ43902.1 - 1.2e-21 76.6 2.5 1.2e-21 76.6 1.7 2.8 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KEZ43902.1 - 2.3e-13 50.0 40.5 2.3e-13 50.0 28.1 1.8 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIA PF03153.8 KEZ43902.1 - 3.2 7.5 37.1 0.67 9.7 19.7 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF87 PF01935.12 KEZ43902.1 - 8.9 6.0 9.1 91 2.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 WSC PF01822.14 KEZ43903.1 - 5.3e-24 83.9 21.5 1.4e-14 53.7 1.1 3.7 4 0 0 4 4 4 2 WSC domain LysM PF01476.15 KEZ43903.1 - 5e-05 23.1 0.1 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 LysM domain Glyco_hydro_18 PF00704.23 KEZ43905.1 - 9.7e-63 212.6 0.3 2.4e-62 211.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Cellulase PF00150.13 KEZ43905.1 - 4.7e-20 71.9 1.8 8e-20 71.1 1.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KEZ43905.1 - 6.1e-07 28.6 0.0 1.4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KEZ43905.1 - 0.0004 20.7 0.0 0.00093 19.5 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KEZ43905.1 - 0.0087 15.2 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase Lipase_GDSL PF00657.17 KEZ43906.1 - 3.8e-19 69.4 0.0 4.8e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ43906.1 - 1.3e-18 67.7 0.0 1.7e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KEZ43906.1 - 3.2e-05 23.7 0.0 4.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M18 PF02127.10 KEZ43907.1 - 5.1e-121 404.1 0.0 5.9e-121 403.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) EXS PF03124.9 KEZ43908.1 - 1.4e-92 310.3 29.7 1.9e-92 310.0 20.6 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KEZ43908.1 - 5.1e-54 183.8 0.3 2.9e-53 181.4 0.0 2.0 2 0 0 2 2 2 1 SPX domain DUF4603 PF15376.1 KEZ43908.1 - 0.00051 17.4 0.2 0.00075 16.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) Nucleoplasmin PF03066.10 KEZ43908.1 - 0.13 11.7 8.4 0.24 10.9 5.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF883 PF05957.8 KEZ43908.1 - 5.8 7.3 8.9 0.18 12.2 1.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Meth_synt_2 PF01717.13 KEZ43909.1 - 1.7e-13 50.2 0.0 2e-05 23.7 0.0 3.0 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KEZ43909.1 - 8.1e-05 22.0 0.0 0.0039 16.5 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Pyr_redox_3 PF13738.1 KEZ43910.1 - 6.9e-18 65.4 0.0 1.7e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ43910.1 - 5.8e-11 41.2 0.0 1.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ43910.1 - 3e-08 32.9 0.0 1.4e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEZ43910.1 - 5.8e-07 29.4 0.0 1.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ43910.1 - 0.02 13.7 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.17 KEZ43911.1 - 3.2e-44 151.2 0.0 4.4e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KEZ43911.1 - 1.5e-26 93.2 0.0 2.4e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ43911.1 - 9.1e-09 35.2 0.0 2e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ43911.1 - 0.00061 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KEZ43911.1 - 0.0042 15.8 0.0 0.0066 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ43911.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TENA_THI-4 PF03070.11 KEZ43912.1 - 0.0035 17.1 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Peptidase_M26_C PF07580.9 KEZ43912.1 - 0.0092 14.3 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 1 M26 IgA1-specific Metallo-endopeptidase C-terminal region GMC_oxred_C PF05199.8 KEZ43914.1 - 3e-08 34.0 0.0 3.3e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase MvaI_BcnI PF15515.1 KEZ43914.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family Amidohydro_2 PF04909.9 KEZ43915.1 - 2.1e-23 83.2 0.0 2.6e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase PAF-AH_p_II PF03403.8 KEZ43916.1 - 2e-37 128.4 0.0 7.8e-32 109.9 0.0 2.7 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.8 KEZ43916.1 - 1.6e-22 80.1 0.0 4.6e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 KEZ43916.1 - 2.3e-22 79.1 0.0 4.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 KEZ43916.1 - 1.6e-13 50.5 1.0 1.6e-08 34.3 0.1 3.6 2 1 0 2 2 2 2 Alpha/beta hydrolase family DUF2424 PF10340.4 KEZ43916.1 - 3.8e-11 42.2 0.0 7.5e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KEZ43916.1 - 3.8e-05 23.6 7.6 0.0031 17.4 0.9 3.3 2 1 0 2 2 2 2 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KEZ43916.1 - 0.0015 17.4 0.0 0.0067 15.3 0.0 2.0 3 0 0 3 3 3 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KEZ43916.1 - 0.0024 16.7 0.0 0.0047 15.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 KEZ43916.1 - 0.0053 16.5 0.4 0.08 12.8 0.0 2.7 3 0 0 3 3 3 1 Putative lysophospholipase DLH PF01738.13 KEZ43916.1 - 0.032 13.4 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Pheromone PF08015.6 KEZ43918.1 - 0.018 15.8 2.5 0.018 15.8 1.7 7.1 4 3 2 6 6 6 0 Fungal mating-type pheromone BRCT PF00533.21 KEZ43918.1 - 0.018 15.1 0.0 0.065 13.3 0.0 2.0 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain F-box PF00646.28 KEZ43921.1 - 0.00013 21.5 0.2 0.00036 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain Jacalin PF01419.12 KEZ43921.1 - 0.061 13.1 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Jacalin-like lectin domain Dynamin_N PF00350.18 KEZ43922.1 - 1.1e-28 100.1 0.3 1.1e-28 100.1 0.2 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEZ43922.1 - 5.4e-11 41.8 0.1 1.6e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KEZ43922.1 - 1.3e-06 28.3 0.1 6.6e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ43922.1 - 0.0024 18.3 0.0 0.0072 16.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KEZ43922.1 - 0.0029 16.8 0.1 1.4 8.1 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B RuBisCO_large PF00016.15 KEZ43922.1 - 0.0077 15.1 0.2 0.14 10.9 0.0 2.5 2 1 1 3 3 3 1 Ribulose bisphosphate carboxylase large chain, catalytic domain AAA_21 PF13304.1 KEZ43922.1 - 0.027 14.4 0.0 0.027 14.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain VirE PF05272.6 KEZ43922.1 - 0.067 12.6 0.2 4 6.8 0.0 2.6 2 0 0 2 2 2 0 Virulence-associated protein E Acetyltransf_6 PF13480.1 KEZ43922.1 - 0.075 12.9 2.2 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_29 PF13555.1 KEZ43922.1 - 0.14 11.7 0.1 0.37 10.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phage_B PF02304.10 KEZ43923.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Scaffold protein B MFS_1 PF07690.11 KEZ43924.1 - 1.2e-09 37.3 40.1 4.1e-08 32.3 8.5 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43924.1 - 1.1e-08 34.1 20.4 3.4e-06 25.9 7.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3592 PF12158.3 KEZ43924.1 - 0.041 13.6 4.6 0.093 12.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3592) Pyr_redox_3 PF13738.1 KEZ43925.1 - 3.3e-20 73.0 0.0 9.3e-17 61.7 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ43925.1 - 1.7e-10 39.7 0.0 9.3e-09 34.0 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ43925.1 - 2e-08 34.1 0.6 5.3e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ43925.1 - 8.2e-08 31.5 0.1 7.9e-07 28.2 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ43925.1 - 0.0011 18.8 0.0 0.0031 17.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KEZ43925.1 - 0.023 13.5 0.0 1.4 7.7 0.0 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ43925.1 - 0.14 11.9 0.0 0.78 9.5 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ring_hydroxyl_A PF00848.14 KEZ43926.1 - 4.9e-23 81.8 4.0 3.7e-15 56.1 2.9 2.4 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KEZ43926.1 - 3.9e-14 51.9 0.0 9.2e-14 50.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ank_2 PF12796.2 KEZ43928.1 - 1.5e-38 130.9 0.5 4.8e-14 52.4 0.0 6.3 4 2 3 7 7 7 4 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43928.1 - 4.9e-32 108.1 2.7 3.9e-08 32.7 0.0 8.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEZ43928.1 - 2.8e-23 81.4 1.1 1.6e-06 28.1 0.0 7.0 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ43928.1 - 1.1e-22 79.9 0.4 3e-09 37.1 0.0 7.8 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43928.1 - 1.5e-21 74.3 0.3 0.0001 22.2 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat AAA_16 PF13191.1 KEZ43928.1 - 0.00058 19.8 0.6 0.0042 17.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEZ43928.1 - 0.00087 19.4 0.0 0.0057 16.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 KEZ43928.1 - 0.011 15.3 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KEZ43928.1 - 0.018 15.2 0.0 0.083 13.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ScdA_N PF04405.9 KEZ43928.1 - 0.25 10.7 3.1 0.25 10.7 0.1 2.6 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) Ank_2 PF12796.2 KEZ43929.1 - 1.6e-19 70.0 0.2 2.7e-09 37.2 0.2 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ43929.1 - 7.3e-11 41.3 5.7 0.034 13.9 0.2 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KEZ43929.1 - 8.5e-11 42.0 1.1 2.6e-05 24.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ43929.1 - 5.8e-09 35.3 1.7 0.23 11.8 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KEZ43929.1 - 2.5e-07 30.7 0.8 0.0065 16.6 0.0 3.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) DUF4129 PF13559.1 KEZ43929.1 - 0.086 12.8 0.1 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) RhgB_N PF09284.5 KEZ43930.1 - 1.2e-78 263.9 0.0 1.6e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KEZ43930.1 - 2.9e-46 157.1 0.0 4.9e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KEZ43930.1 - 4.5e-15 55.5 0.4 1.3e-14 54.0 0.1 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II Abhydrolase_3 PF07859.8 KEZ43931.1 - 4e-17 62.4 0.0 6.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.20 KEZ43932.1 - 2.7e-19 69.3 0.0 4.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ43932.1 - 3.1e-07 29.7 0.0 7.4e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase GMC_oxred_N PF00732.14 KEZ43933.1 - 9.9e-61 205.4 0.0 2.1e-60 204.3 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ43933.1 - 5.5e-29 101.3 0.0 1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KEZ43933.1 - 7.8e-05 21.7 0.2 0.00017 20.6 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ43933.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ43933.1 - 0.13 11.1 0.0 0.53 9.1 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short_C2 PF13561.1 KEZ43934.1 - 8e-19 68.3 0.0 9.7e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ43934.1 - 6.8e-15 55.3 2.0 8.6e-15 55.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ43934.1 - 3.3e-07 30.1 0.2 4.9e-07 29.5 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEZ43934.1 - 3.5e-05 23.8 0.6 5.3e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KEZ43934.1 - 0.0019 17.8 0.2 0.003 17.2 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 KEZ43934.1 - 0.0037 15.9 0.0 0.0049 15.5 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NAD_binding_7 PF13241.1 KEZ43934.1 - 0.0072 16.5 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N PF00107.21 KEZ43934.1 - 0.037 13.5 1.2 0.092 12.2 0.3 2.0 1 1 1 2 2 2 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 KEZ43934.1 - 0.05 13.6 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain AdoHcyase_NAD PF00670.16 KEZ43934.1 - 0.07 12.9 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 KEZ43934.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KEZ43934.1 - 0.26 11.1 2.0 0.45 10.3 1.4 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 KEZ43936.1 - 1.1e-41 142.8 31.3 1.1e-41 142.8 21.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ43936.1 - 0.00096 17.4 4.8 0.0015 16.8 3.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Bac_luciferase PF00296.15 KEZ43938.1 - 1.2e-65 221.6 2.3 1.7e-65 221.1 1.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 KEZ43939.1 - 7e-18 64.4 30.6 1.1e-17 63.8 21.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family adh_short PF00106.20 KEZ43940.1 - 4.4e-07 29.9 0.1 6.9e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KEZ43940.1 - 0.0023 17.4 0.0 0.0036 16.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEZ43940.1 - 0.084 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 KEZ43941.1 - 3.8e-13 49.6 2.2 9.7e-13 48.3 1.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43941.1 - 2.5e-05 24.1 0.3 3.3e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43941.1 - 4.2e-05 23.2 0.1 8.4e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KEZ43941.1 - 6e-05 22.5 0.4 0.00023 20.7 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KEZ43941.1 - 0.033 14.1 0.1 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain FMO-like PF00743.14 KEZ43942.1 - 1.4e-55 188.5 0.0 2.4e-55 187.7 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEZ43942.1 - 1.3e-24 87.3 0.0 1.6e-23 83.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ43942.1 - 1.7e-12 47.6 0.0 2.2e-10 40.7 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ43942.1 - 2.4e-10 40.3 0.7 6.6e-08 32.4 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KEZ43942.1 - 1.4e-08 34.0 0.0 4.9e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KEZ43942.1 - 1.3e-05 24.2 5.0 0.021 13.7 0.2 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KEZ43942.1 - 7.3e-05 22.9 0.8 0.23 11.7 0.0 3.2 2 1 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KEZ43942.1 - 8.7e-05 22.4 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 KEZ43942.1 - 0.00021 20.7 0.2 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 KEZ43942.1 - 0.00046 20.0 0.3 0.0046 16.8 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ43942.1 - 0.0006 19.0 0.2 0.58 9.2 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 KEZ43942.1 - 0.00095 18.9 2.9 0.072 12.9 0.1 2.8 3 0 0 3 3 3 1 ThiF family ELFV_dehydrog PF00208.16 KEZ43942.1 - 0.0038 16.8 0.2 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HI0933_like PF03486.9 KEZ43942.1 - 0.013 14.0 0.1 3.3 6.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein IlvN PF07991.7 KEZ43942.1 - 0.014 14.7 0.1 0.46 9.8 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KEZ43942.1 - 0.02 14.9 0.6 0.99 9.4 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Shikimate_DH PF01488.15 KEZ43942.1 - 0.059 13.4 0.5 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KEZ43942.1 - 0.059 13.7 2.8 2.1 8.7 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ43942.1 - 0.065 12.2 0.0 0.33 9.9 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KEZ43942.1 - 0.069 12.7 1.9 0.35 10.5 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KEZ43942.1 - 0.14 11.2 0.1 0.92 8.5 0.1 2.1 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 KEZ43942.1 - 1.5 8.2 4.1 0.55 9.6 0.1 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Grp1_Fun34_YaaH PF01184.14 KEZ43943.1 - 3.5e-23 82.0 16.1 4.5e-23 81.6 11.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Abhydrolase_6 PF12697.2 KEZ43944.1 - 4.8e-11 42.9 0.1 6.1e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ43944.1 - 5.2e-05 23.0 0.0 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAP2 PF01569.16 KEZ43945.1 - 2.5e-08 33.6 0.5 5.7e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily AA_permease PF00324.16 KEZ43946.1 - 5.7e-100 334.9 35.9 9.6e-100 334.1 24.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ43946.1 - 9.7e-21 73.7 34.3 1.3e-20 73.3 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AhpC-TSA PF00578.16 KEZ43947.1 - 1.7e-37 127.8 0.0 2.3e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KEZ43947.1 - 2.3e-14 53.1 0.0 3.1e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KEZ43947.1 - 2.2e-12 46.3 0.0 3.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin HNH_2 PF13391.1 KEZ43948.1 - 1.9e-05 24.3 0.1 3.5e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_45 PF02015.11 KEZ43949.1 - 7.5e-26 91.4 5.9 8.4e-26 91.2 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 p450 PF00067.17 KEZ43950.1 - 1.5e-33 116.0 0.0 2.2e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF4404 PF14357.1 KEZ43951.1 - 0.23 11.9 2.3 0.96 9.9 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Malic_M PF03949.10 KEZ43952.1 - 1.1e-83 280.7 0.2 1.4e-83 280.4 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KEZ43952.1 - 6.7e-61 205.0 0.0 1.1e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PTR2 PF00854.16 KEZ43954.1 - 3.8e-44 150.9 10.4 3.3e-24 85.3 5.0 2.4 2 1 0 2 2 2 2 POT family MFS_1 PF07690.11 KEZ43955.1 - 2.3e-20 72.6 47.1 1.1e-18 67.1 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 KEZ43956.1 - 3.2e-49 167.6 0.0 4.5e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AzlD PF05437.7 KEZ43956.1 - 0.081 12.8 0.2 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) HCV_NS5a PF01506.14 KEZ43956.1 - 0.44 10.2 1.4 0.66 9.7 0.1 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Histidinol_dh PF00815.15 KEZ43957.1 - 8.8e-118 393.5 0.0 1.1e-117 393.2 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DnaJ-X PF14308.1 KEZ43957.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing adh_short PF00106.20 KEZ43958.1 - 6.9e-27 94.4 2.6 1.1e-26 93.6 1.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43958.1 - 4.5e-19 69.1 0.3 5.1e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43958.1 - 1.7e-13 50.6 0.7 3e-13 49.8 0.5 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KEZ43958.1 - 0.057 13.2 0.1 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thioredoxin_6 PF13848.1 KEZ43958.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Cupin_2 PF07883.6 KEZ43959.1 - 2.4e-09 36.5 0.0 4.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KEZ43959.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF4536 PF15055.1 KEZ43960.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) AAA_12 PF13087.1 KEZ43961.1 - 3.6e-22 78.7 0.0 5.7e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ43961.1 - 6e-11 42.3 0.0 2.6e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ43961.1 - 5.8e-05 22.7 0.1 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 KEZ43961.1 - 0.0026 17.8 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 KEZ43961.1 - 0.0081 15.7 0.0 0.058 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 KEZ43961.1 - 0.038 13.6 0.0 0.95 9.0 0.0 2.5 3 0 0 3 3 3 0 Helicase MFS_1 PF07690.11 KEZ43962.1 - 1.6e-35 122.4 29.5 1.6e-35 122.4 20.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43962.1 - 1e-11 44.1 13.5 1e-11 44.1 9.3 3.8 2 2 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KEZ43962.1 - 0.0011 17.2 6.2 0.0021 16.3 4.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrophobin PF01185.13 KEZ43963.1 - 4.9e-10 39.7 9.4 7.6e-10 39.1 6.5 1.4 1 0 0 1 1 1 1 Fungal hydrophobin Glyco_hydro_63 PF03200.11 KEZ43963.1 - 0.023 12.5 0.0 0.023 12.5 0.0 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase ASC PF00858.19 KEZ43963.1 - 0.029 13.0 0.1 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF3328 PF11807.3 KEZ43964.1 - 2.6e-31 108.9 0.7 2.9e-31 108.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.20 KEZ43965.1 - 1.1e-20 74.2 1.0 1.4e-20 73.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ43965.1 - 2.1e-09 37.5 0.0 2.6e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ43965.1 - 1.2e-05 25.0 0.5 1.8e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ43965.1 - 0.0063 15.9 0.1 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3335 PF11814.3 KEZ43965.1 - 0.022 13.8 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family 2-Hacid_dh_C PF02826.14 KEZ43965.1 - 0.065 12.3 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_S8 PF00082.17 KEZ43966.1 - 3e-47 161.1 16.4 4e-47 160.6 11.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEZ43966.1 - 7e-12 45.7 0.0 1.3e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 GSDH PF07995.6 KEZ43968.1 - 0.00021 20.5 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 KEZ43968.1 - 0.0011 18.3 0.1 0.0036 16.7 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 KEZ43968.1 - 0.085 12.5 0.0 0.46 10.2 0.0 2.3 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RCC1_2 PF13540.1 KEZ43968.1 - 0.12 11.9 1.1 6 6.6 0.0 3.1 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Ndc1_Nup PF09531.5 KEZ43969.1 - 0.015 13.7 0.7 0.026 12.9 0.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup p450 PF00067.17 KEZ43970.1 - 1.3e-69 234.9 0.0 1.5e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 KEZ43971.1 - 2.8e-37 128.4 0.0 3.6e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ43971.1 - 2e-33 115.7 0.0 3.1e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ43971.1 - 0.047 12.5 1.3 0.21 10.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Tyrosinase PF00264.15 KEZ43972.1 - 4.1e-30 105.5 0.1 5.6e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Catalase PF00199.14 KEZ43973.1 - 2.3e-173 576.2 0.1 2.7e-173 576.0 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KEZ43973.1 - 2.1e-09 37.1 0.0 5.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive TauD PF02668.11 KEZ43974.1 - 2.7e-35 122.3 0.1 3.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Arginase PF00491.16 KEZ43975.1 - 1.8e-88 296.4 0.0 2.1e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KEZ43975.1 - 0.051 13.7 0.1 0.1 12.7 0.0 1.5 1 1 1 2 2 2 0 UPF0489 domain MatE PF01554.13 KEZ43976.1 - 3.9e-54 182.6 16.0 6.5e-32 110.3 1.8 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KEZ43976.1 - 1e-08 35.1 7.3 1e-08 35.1 5.1 3.9 2 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Dispanin PF04505.7 KEZ43976.1 - 0.16 11.5 2.3 0.21 11.1 0.4 2.0 2 0 0 2 2 2 0 Interferon-induced transmembrane protein MFS_1 PF07690.11 KEZ43977.1 - 8.2e-45 153.0 43.7 5.1e-38 130.6 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ43977.1 - 9.2e-14 50.8 10.9 9.2e-14 50.8 7.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KEZ43977.1 - 0.00025 19.3 4.8 0.00025 19.3 3.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Lipase_GDSL_2 PF13472.1 KEZ43978.1 - 1.5e-12 47.9 0.0 3.9e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ43978.1 - 1.3e-11 44.7 0.0 2.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CHAT PF12770.2 KEZ43978.1 - 2.2e-09 36.8 0.0 4.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.7 KEZ43978.1 - 2.1e-05 24.2 0.0 4.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Lipase_GDSL_3 PF14606.1 KEZ43978.1 - 6.9e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AAA_22 PF13401.1 KEZ43978.1 - 0.0029 17.7 0.0 0.01 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KEZ43978.1 - 0.0093 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Peptidase_C25 PF01364.13 KEZ43978.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C25 MobB PF03205.9 KEZ43978.1 - 0.084 12.5 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Transferase PF02458.10 KEZ43979.1 - 1.3e-06 27.1 0.0 2.9e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Transferase family GST_C_3 PF14497.1 KEZ43980.1 - 1.3e-09 38.3 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEZ43980.1 - 5.4e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.16 KEZ43981.1 - 2.4e-48 164.5 0.6 3e-46 157.6 0.4 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF3136 PF11334.3 KEZ43981.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) PBP_like_2 PF12849.2 KEZ43982.1 - 1.5e-06 27.8 3.5 2e-06 27.4 2.4 1.1 1 0 0 1 1 1 1 PBP superfamily domain Glyco_hydro_61 PF03443.9 KEZ43983.1 - 1.3e-50 172.2 0.1 1.5e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glycogen_syn PF05693.8 KEZ43984.1 - 1.6e-229 763.3 0.0 2e-229 763.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KEZ43984.1 - 4.7e-07 29.3 0.0 7.6e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KEZ43984.1 - 2.2e-06 27.3 0.1 4.9e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KEZ43984.1 - 0.00032 20.8 0.0 0.00092 19.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 KEZ43984.1 - 0.018 15.1 0.0 0.066 13.3 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 PHO4 PF01384.15 KEZ43985.1 - 3.4e-108 361.1 14.2 3.9e-108 360.9 9.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Dioxygenase_C PF00775.16 KEZ43986.1 - 2.2e-43 147.6 0.0 2.9e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KEZ43986.1 - 2e-12 46.9 0.1 3.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KEZ43986.1 - 0.015 15.3 0.0 0.049 13.6 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 KEZ43986.1 - 0.064 13.0 0.5 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Cna protein B-type domain Exo_endo_phos PF03372.18 KEZ43987.1 - 4.4e-11 43.1 0.3 6.9e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 KEZ43988.1 - 2.2e-18 66.1 9.1 2.7e-13 49.3 2.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KEZ43988.1 - 0.0001 20.9 0.4 0.0002 19.9 0.1 1.5 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like DUF1228 PF06779.9 KEZ43988.1 - 0.0032 17.4 0.7 0.0058 16.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) Fungal_trans PF04082.13 KEZ43989.1 - 4.4e-08 32.3 0.1 9.9e-08 31.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ43989.1 - 0.00033 20.5 10.4 0.0007 19.4 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 KEZ43990.1 - 8.6e-49 166.2 0.0 7.7e-43 146.6 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III Glyco_hydro_2_N PF02837.13 KEZ43991.1 - 2e-08 34.0 0.0 4.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KEZ43991.1 - 2e-06 28.2 0.0 1.2e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Zn_clus PF00172.13 KEZ43993.1 - 0.00011 22.0 6.6 0.00023 21.0 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KEZ43994.1 - 5.2e-75 252.7 18.1 6.4e-75 252.4 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ43994.1 - 5.6e-20 71.3 41.9 8.5e-18 64.1 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ43995.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Beta-lactamase PF00144.19 KEZ43996.1 - 4.9e-30 104.6 0.1 7.8e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Bac_luciferase PF00296.15 KEZ43997.1 - 1.2e-63 215.0 0.0 1.5e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 KEZ43998.1 - 4.4e-31 107.8 24.5 4.4e-31 107.8 17.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 KEZ43999.1 - 2.1e-19 70.4 0.0 3.3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ43999.1 - 2.9e-14 52.1 0.1 3.2e-13 48.7 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ43999.1 - 2.4e-08 33.8 0.1 8.4e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ43999.1 - 4.2e-05 22.6 0.3 0.0042 16.0 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KEZ43999.1 - 0.0025 16.9 0.2 0.0078 15.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 KEZ43999.1 - 0.012 15.3 0.4 0.2 11.4 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.11 KEZ44001.1 - 5e-35 120.8 29.4 1.7e-34 119.1 19.4 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S8 PF00082.17 KEZ44002.1 - 1.8e-43 148.7 8.6 2.5e-43 148.2 6.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEZ44002.1 - 1.7e-14 54.1 0.0 3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 ADH_zinc_N PF00107.21 KEZ44003.1 - 6.7e-18 64.4 0.0 1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ44003.1 - 5.7e-06 27.2 0.0 1e-05 26.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3938 PF13074.1 KEZ44005.1 - 0.13 12.1 2.1 0.32 10.8 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3938) p450 PF00067.17 KEZ44006.1 - 2.7e-30 105.3 0.2 4.3e-18 65.0 0.7 2.1 1 1 1 2 2 2 2 Cytochrome P450 GSu_C4xC__C2xCH PF09698.5 KEZ44007.1 - 0.026 14.6 2.3 0.026 14.6 1.6 2.2 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) NAD_binding_10 PF13460.1 KEZ44008.1 - 2.8e-07 30.7 0.0 4.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Peptidase_M43 PF05572.8 KEZ44010.1 - 4.4e-18 65.3 0.1 6.8e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KEZ44010.1 - 8e-08 32.4 0.2 1.1e-07 31.9 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KEZ44010.1 - 9.6e-06 25.7 0.4 1.7e-05 24.9 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KEZ44010.1 - 1.3e-05 25.7 0.1 3e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KEZ44010.1 - 0.0029 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KEZ44010.1 - 0.0031 16.4 0.4 0.0038 16.1 0.3 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.1 KEZ44010.1 - 0.093 12.2 1.1 0.14 11.7 0.8 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SET PF00856.23 KEZ44011.1 - 8.5e-12 45.6 0.1 5e-10 39.9 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.1 KEZ44011.1 - 0.0035 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat FtsX PF02687.16 KEZ44012.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 FtsX-like permease family Romo1 PF10247.4 KEZ44012.1 - 0.14 12.3 2.3 8.9 6.5 0.1 2.7 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Ank_2 PF12796.2 KEZ44013.1 - 1.3e-19 70.2 0.1 4.6e-14 52.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ44013.1 - 2.1e-12 46.2 3.4 0.0045 16.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 KEZ44013.1 - 7.4e-10 38.0 1.0 0.077 13.2 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KEZ44013.1 - 2.2e-08 34.3 0.6 0.0003 21.2 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ44013.1 - 5.9e-07 29.5 6.4 0.18 12.1 0.0 6.1 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Stig1 PF04885.8 KEZ44013.1 - 1.4e-06 28.5 2.8 3.1e-06 27.4 1.9 1.5 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 Copper-fist PF00649.13 KEZ44014.1 - 2.2e-13 49.1 3.7 2.2e-13 49.1 2.6 1.5 2 0 0 2 2 2 1 Copper fist DNA binding domain Phospholip_A2_3 PF09056.6 KEZ44015.1 - 1.3e-46 157.3 0.3 1.7e-46 157.0 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Sugar_tr PF00083.19 KEZ44016.1 - 4.4e-84 282.6 18.5 5.1e-84 282.4 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ44016.1 - 7.2e-22 77.5 42.0 7.9e-17 60.9 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ44016.1 - 0.00031 19.0 4.1 0.00031 19.0 2.9 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 KEZ44016.1 - 0.65 10.0 8.0 2.3 8.3 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) ADH_N PF08240.7 KEZ44017.1 - 1.3e-29 102.1 3.2 2.5e-29 101.2 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ44017.1 - 9.3e-26 89.9 1.2 2e-25 88.8 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ44017.1 - 2e-07 31.9 0.0 3.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAS PF03059.11 KEZ44017.1 - 0.02 14.0 0.1 0.05 12.7 0.0 1.7 1 1 0 1 1 1 0 Nicotianamine synthase protein TrkA_N PF02254.13 KEZ44017.1 - 0.024 14.6 0.9 0.041 13.8 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain ADH_N_assoc PF13823.1 KEZ44017.1 - 0.066 12.8 0.2 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated MIP PF00230.15 KEZ44018.1 - 4.7e-07 29.5 0.1 6.1e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein MFS_1 PF07690.11 KEZ44019.1 - 1.6e-18 66.6 18.4 1.6e-18 66.6 12.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Rab5ip PF07019.7 KEZ44019.1 - 0.054 13.6 2.2 0.21 11.7 1.5 2.1 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) LigB PF02900.13 KEZ44020.1 - 1.1e-34 119.7 0.1 1.3e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3632 PF12311.3 KEZ44021.1 - 7.9e-26 90.9 1.2 1.4e-25 90.1 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) E1-E2_ATPase PF00122.15 KEZ44022.1 - 4.8e-68 228.6 0.0 4.8e-68 228.6 0.0 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ44022.1 - 5.5e-24 85.7 0.0 1e-23 84.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ44022.1 - 1.6e-12 48.0 0.0 3.9e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ44022.1 - 4.5e-11 42.0 0.0 1.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEZ44022.1 - 0.0012 18.4 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AphA_like PF14557.1 KEZ44022.1 - 0.021 14.3 0.1 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator Enolase_C PF00113.17 KEZ44023.1 - 2.1e-114 381.4 0.0 2.7e-114 381.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KEZ44023.1 - 5.5e-51 171.9 0.1 2e-50 170.1 0.0 1.9 2 0 0 2 2 2 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KEZ44023.1 - 0.024 14.5 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like Lipase_GDSL PF00657.17 KEZ44024.1 - 8.3e-17 61.7 0.1 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ44024.1 - 6e-12 46.0 0.1 1.4e-11 44.8 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KEZ44024.1 - 3.5e-07 30.1 0.0 2.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF2282 PF10048.4 KEZ44024.1 - 0.037 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) DUF2306 PF10067.4 KEZ44024.1 - 0.12 12.5 0.2 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) GMC_oxred_N PF00732.14 KEZ44025.1 - 4.4e-60 203.3 0.0 7.1e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ44025.1 - 6.5e-27 94.5 0.0 1.4e-26 93.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ44025.1 - 1.5e-06 27.3 0.7 0.023 13.5 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ44025.1 - 1.4e-05 24.1 1.5 0.00044 19.2 0.8 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ44025.1 - 0.00013 21.8 1.0 0.00034 20.5 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KEZ44025.1 - 0.00041 20.2 0.2 0.4 10.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ44025.1 - 0.00049 20.2 0.1 1.6 8.7 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ44025.1 - 0.00098 19.4 0.2 0.003 17.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KEZ44025.1 - 0.0071 14.7 0.0 0.011 14.1 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Thi4 PF01946.12 KEZ44025.1 - 0.0071 15.4 0.2 0.013 14.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KEZ44025.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 KEZ44025.1 - 0.14 10.5 0.1 0.24 9.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein HPP PF04982.8 KEZ44028.1 - 6.3e-31 106.7 5.7 7.9e-31 106.3 3.9 1.1 1 0 0 1 1 1 1 HPP family CcmD PF04995.9 KEZ44028.1 - 1.1 9.0 6.7 2.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Ank_4 PF13637.1 KEZ44030.1 - 2.2e-13 50.3 0.1 2.2e-06 28.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEZ44030.1 - 1.7e-10 41.1 0.0 5.3e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ44030.1 - 5.3e-10 38.6 0.1 1e-06 28.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEZ44030.1 - 1.7e-07 31.2 0.8 0.0018 18.4 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ44030.1 - 1.9e-06 27.5 0.0 8.2e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Med3 PF11593.3 KEZ44030.1 - 1.7 7.7 7.8 1.8 7.6 5.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Baculo_PEP_C PF04513.7 KEZ44031.1 - 0.023 14.5 12.7 0.27 11.0 5.0 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPPII_N PF12583.3 KEZ44032.1 - 0.078 13.1 0.1 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal EGF_CA PF07645.10 KEZ44032.1 - 7 6.7 8.4 0.36 10.8 1.8 1.9 1 1 1 2 2 2 0 Calcium-binding EGF domain MFS_1 PF07690.11 KEZ44033.1 - 3.3e-28 98.4 25.0 3.3e-28 98.4 17.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M74 PF03411.8 KEZ44033.1 - 0.095 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase ESSS PF10183.4 KEZ44033.1 - 6.5 7.2 8.7 1.4 9.3 0.0 3.5 3 1 1 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TauD PF02668.11 KEZ44034.1 - 1.8e-51 175.2 0.0 2.3e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TPR_12 PF13424.1 KEZ44037.1 - 7.4e-09 35.4 5.0 4.6e-07 29.6 0.3 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 KEZ44037.1 - 2e-08 34.4 0.0 5.4e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KEZ44037.1 - 5.2e-08 32.0 0.0 9.4e-08 31.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KEZ44037.1 - 0.00047 19.9 0.1 0.0025 17.5 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase TPR_11 PF13414.1 KEZ44037.1 - 0.01 15.4 8.1 0.014 15.0 0.7 3.8 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 KEZ44037.1 - 0.065 13.1 9.5 0.17 11.8 0.9 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ44037.1 - 0.19 11.4 8.0 0.6 9.8 1.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C15 PF01470.12 KEZ44039.1 - 0.00031 20.6 0.0 0.0069 16.2 0.0 2.1 2 0 0 2 2 2 2 Pyroglutamyl peptidase SNF2_N PF00176.18 KEZ44040.1 - 1.9e-65 220.6 0.1 2.6e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ44040.1 - 1.7e-12 47.0 0.0 5.1e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ44040.1 - 5.9e-10 38.8 0.1 2.7e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KEZ44040.1 - 1.2e-06 28.4 0.1 2.4e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 KEZ44040.1 - 0.0079 15.9 3.3 0.027 14.1 2.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KEZ44040.1 - 0.012 15.2 3.6 0.035 13.6 2.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 KEZ44040.1 - 0.023 14.3 9.3 0.054 13.2 6.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.10 KEZ44040.1 - 0.03 13.7 0.1 0.03 13.7 0.1 1.8 2 0 0 2 2 2 0 DEAD_2 zf-C3HC4 PF00097.20 KEZ44040.1 - 0.078 12.6 6.4 0.24 11.0 4.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ44040.1 - 0.079 12.8 8.4 0.28 11.0 5.8 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 KEZ44040.1 - 0.11 12.2 11.9 0.018 14.6 5.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ44040.1 - 1.9 8.5 13.6 0.34 10.9 6.0 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.7 KEZ44041.1 - 2.8e-13 49.8 0.0 7.1e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ44041.1 - 5.1e-09 36.3 2.4 3.4e-07 30.4 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain zf-C2H2_4 PF13894.1 KEZ44041.1 - 2e-07 30.8 35.2 0.039 14.2 4.4 7.1 7 0 0 7 7 7 3 C2H2-type zinc finger AAA_22 PF13401.1 KEZ44041.1 - 1e-05 25.6 0.0 5.1e-05 23.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEZ44041.1 - 3.2e-05 22.9 0.1 8.2e-05 21.5 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain zf-C2H2 PF00096.21 KEZ44041.1 - 6.7e-05 22.9 39.4 0.0087 16.3 5.5 6.2 7 0 0 7 7 6 3 Zinc finger, C2H2 type AAA PF00004.24 KEZ44041.1 - 0.00028 21.0 0.0 0.0026 17.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KEZ44041.1 - 0.00056 19.6 1.0 0.0011 18.7 0.1 2.0 2 0 0 2 2 2 1 Archaeal ATPase zf-C2H2_jaz PF12171.3 KEZ44041.1 - 0.0011 18.9 23.0 0.013 15.6 3.3 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding AAA_35 PF14516.1 KEZ44041.1 - 0.0022 16.7 0.1 0.0036 15.9 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain KaiC PF06745.8 KEZ44041.1 - 0.0045 16.1 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 KaiC zf-met PF12874.2 KEZ44041.1 - 0.011 15.8 18.8 0.049 13.8 3.8 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type AAA_14 PF13173.1 KEZ44041.1 - 0.015 15.2 0.0 0.45 10.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KEZ44041.1 - 0.015 14.7 0.0 0.089 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain zf-H2C2_2 PF13465.1 KEZ44041.1 - 0.023 14.9 0.1 0.023 14.9 0.1 6.0 7 1 0 7 7 6 0 Zinc-finger double domain AAA_17 PF13207.1 KEZ44041.1 - 0.029 15.1 0.9 0.27 12.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KEZ44041.1 - 0.062 13.4 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 KEZ44041.1 - 0.11 12.3 0.0 0.42 10.3 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 KEZ44041.1 - 0.25 11.3 0.0 1.5 8.8 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Aminotran_3 PF00202.16 KEZ44042.1 - 1.1e-14 54.1 0.0 1.5e-07 30.6 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-III adh_short PF00106.20 KEZ44043.1 - 1.9e-32 112.4 2.8 2.9e-32 111.9 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ44043.1 - 2.2e-32 112.7 0.3 2.5e-32 112.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ44043.1 - 5.2e-13 49.0 0.3 7.2e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ44043.1 - 0.0047 16.4 0.9 0.039 13.3 0.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 KEZ44043.1 - 0.061 13.1 1.5 0.084 12.7 0.2 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Cytochrome_CBB3 PF13442.1 KEZ44043.1 - 0.082 13.0 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Zn_clus PF00172.13 KEZ44044.1 - 0.099 12.5 4.8 0.24 11.3 3.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_4 PF08386.5 KEZ44045.1 - 1.6e-19 69.7 0.0 3.5e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEZ44045.1 - 5.8e-06 26.0 0.0 0.048 13.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ44045.1 - 7.5e-06 25.9 0.2 5.9e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ44045.1 - 0.025 14.3 0.0 0.16 11.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-Apc11 PF12861.2 KEZ44045.1 - 0.086 12.6 0.6 0.24 11.2 0.0 2.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger HCO3_cotransp PF00955.16 KEZ44046.1 - 4.9e-54 183.8 10.3 4.7e-31 108.0 1.3 2.1 2 0 0 2 2 2 2 HCO3- transporter family DUF3953 PF13129.1 KEZ44046.1 - 0.84 9.3 5.3 13 5.5 0.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) K_oxygenase PF13434.1 KEZ44047.1 - 1.4e-11 43.9 0.0 4.2e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KEZ44047.1 - 4.7e-07 30.0 0.0 0.025 14.6 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ44047.1 - 1.3e-05 25.2 0.0 0.02 14.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ44047.1 - 0.00031 20.5 0.6 0.099 12.4 0.1 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KEZ44047.1 - 0.0067 15.3 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KEZ44047.1 - 0.01 14.3 0.0 0.32 9.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 KEZ44047.1 - 0.022 13.8 1.0 0.16 10.9 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 KEZ44047.1 - 0.03 14.3 0.7 0.12 12.4 0.0 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ44047.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 KEZ44047.1 - 0.086 11.7 0.6 1.7 7.4 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KEZ44047.1 - 0.15 12.2 0.0 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_23 PF13489.1 KEZ44048.1 - 1.4e-25 89.8 0.0 2.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44048.1 - 5e-09 35.9 0.0 2.6e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44048.1 - 1.7e-08 35.0 0.0 1.7e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44048.1 - 6e-08 33.0 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44048.1 - 1.6e-05 25.2 0.0 6.6e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44048.1 - 0.00017 21.8 0.0 0.00039 20.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ44048.1 - 0.0035 16.4 0.0 0.0092 15.0 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KEZ44048.1 - 0.015 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KEZ44048.1 - 0.036 14.1 0.0 0.096 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain TrmB PF01978.14 KEZ44048.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MTS PF05175.9 KEZ44048.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 KEZ44048.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.17 KEZ44049.1 - 1.9e-56 191.5 0.0 2.5e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol3_chi PF04364.8 KEZ44049.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC Glyco_hydro_61 PF03443.9 KEZ44050.1 - 1.4e-36 126.4 0.0 1.6e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_19 PF03427.8 KEZ44051.1 - 0.019 14.7 12.9 0.049 13.3 8.9 1.7 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) LRV_FeS PF05484.6 KEZ44051.1 - 0.068 12.7 1.0 0.77 9.3 0.1 2.1 1 1 1 2 2 2 0 LRV protein FeS4 cluster DUF1180 PF06679.7 KEZ44051.1 - 0.32 10.8 2.3 0.33 10.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Methyltransf_23 PF13489.1 KEZ44052.1 - 4.4e-16 59.0 0.0 7.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44052.1 - 1.4e-08 35.0 0.0 7.4e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44052.1 - 2.3e-08 33.7 0.0 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44052.1 - 5.3e-08 33.2 0.0 1.6e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44052.1 - 2.7e-07 31.1 0.0 1.1e-05 25.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44052.1 - 2.2e-06 27.9 0.0 1.2e-05 25.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ44052.1 - 3.4e-05 23.9 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ44052.1 - 0.0086 16.1 0.0 0.041 13.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ44052.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KEZ44052.1 - 0.018 14.1 0.0 1.5 7.8 0.0 2.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ44052.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 KEZ44052.1 - 0.066 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KEZ44052.1 - 0.087 11.8 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ARGLU PF15346.1 KEZ44053.1 - 0.84 9.4 33.0 1.8 8.3 22.9 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 HlyD PF00529.15 KEZ44053.1 - 1.9 7.7 21.3 3 7.0 14.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF874 PF05917.6 KEZ44053.1 - 6.7 5.4 8.5 11 4.8 5.9 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Mnd1 PF03962.10 KEZ44053.1 - 8.8 5.9 14.3 16 5.1 9.9 1.4 1 0 0 1 1 1 0 Mnd1 family LysM PF01476.15 KEZ44055.1 - 6.5e-11 41.9 0.6 3.4e-06 26.8 0.2 2.4 2 0 0 2 2 2 2 LysM domain RbcS PF12338.3 KEZ44055.1 - 0.014 15.1 0.1 0.014 15.1 0.1 4.0 4 1 0 4 4 4 0 Ribulose-1,5-bisphosphate carboxylase small subunit Mucin PF01456.12 KEZ44055.1 - 0.1 12.3 21.4 0.014 15.2 8.9 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein adh_short PF00106.20 KEZ44056.1 - 2.9e-11 43.5 0.0 5.4e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ44056.1 - 2.5e-09 37.2 0.0 3.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEZ44056.1 - 6.7e-09 35.5 0.0 1.2e-07 31.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEZ44056.1 - 1.2e-07 31.5 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KEZ44056.1 - 7.5e-05 21.7 0.1 0.0011 17.9 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.8 KEZ44056.1 - 0.00029 20.1 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KEZ44056.1 - 0.027 13.1 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEZ44056.1 - 0.039 13.9 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEZ44056.1 - 0.086 11.7 0.1 0.33 9.7 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 KEZ44057.1 - 1.6e-06 27.1 36.6 1.6e-06 27.1 25.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEZ44057.1 - 5.9e-05 22.6 1.6 0.00017 21.1 1.1 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 NPP1 PF05630.6 KEZ44059.1 - 6.1e-82 274.3 2.4 1.1e-81 273.5 0.8 2.1 2 0 0 2 2 2 1 Necrosis inducing protein (NPP1) VCBS PF13517.1 KEZ44059.1 - 3.1e-35 120.3 76.3 8.2e-09 35.7 5.8 8.6 4 2 5 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEZ44059.1 - 1.7e-20 72.1 80.0 0.00039 20.0 2.0 10.5 10 0 0 10 10 10 8 FG-GAP repeat HeLo PF14479.1 KEZ44059.1 - 5e-16 59.0 0.0 7.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Lipase_GDSL PF00657.17 KEZ44059.1 - 4.8e-15 56.0 0.2 4.8e-15 56.0 0.1 2.6 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ44059.1 - 2e-12 47.5 1.0 2e-12 47.5 0.7 2.1 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 KEZ44059.1 - 3.9e-12 45.9 25.2 0.44 9.9 0.1 9.0 8 1 1 9 9 9 6 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.1 KEZ44059.1 - 0.00085 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cyclase PF04199.8 KEZ44060.1 - 0.037 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative cyclase Fungal_trans_2 PF11951.3 KEZ44060.1 - 0.05 12.1 0.0 0.076 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3176 PF11374.3 KEZ44061.1 - 2.5e-30 104.6 0.6 4.9e-30 103.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) ApbA_C PF08546.6 KEZ44062.1 - 1.9e-32 111.9 0.0 3.1e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KEZ44062.1 - 1.3e-28 99.3 0.0 1.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GerPB PF10803.3 KEZ44063.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Spore germination GerPB SYS1 PF09801.4 KEZ44065.1 - 6.8e-47 159.1 1.0 7.8e-47 158.9 0.7 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DctQ PF04290.7 KEZ44065.1 - 1.1 8.9 9.1 0.19 11.4 3.4 1.8 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Aspzincin_M35 PF14521.1 KEZ44067.1 - 0.014 15.9 0.0 0.043 14.3 0.0 1.8 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase PIP5K PF01504.13 KEZ44069.1 - 5.8e-87 290.9 0.2 8.4e-87 290.4 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Acyl-CoA_dh_1 PF00441.19 KEZ44070.1 - 2.6e-23 82.7 0.8 4.9e-23 81.8 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEZ44070.1 - 1.4e-22 80.4 0.6 3.7e-22 79.0 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ44070.1 - 8.2e-16 57.2 0.1 2.2e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KEZ44070.1 - 4.8e-07 30.1 0.5 9e-07 29.2 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 KEZ44070.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal UQ_con PF00179.21 KEZ44071.1 - 2.7e-51 172.6 0.0 3.1e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ44071.1 - 6.4e-05 22.7 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KEZ44071.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KEZ44071.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.7 KEZ44072.1 - 5.1e-32 110.9 0.0 9.1e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEZ44072.1 - 7.3e-21 74.0 0.0 2.4e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KEZ44072.1 - 1e-16 61.1 15.9 4.3e-16 59.1 5.1 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KEZ44072.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KEZ44072.1 - 0.089 13.3 0.0 0.83 10.2 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain CPSF100_C PF13299.1 KEZ44074.1 - 9.4e-42 142.9 0.2 1.6e-41 142.1 0.2 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KEZ44074.1 - 7.6e-26 90.5 0.0 2.2e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 KEZ44074.1 - 1.5e-05 24.6 0.0 5.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase PBP_sp32 PF07222.7 KEZ44074.1 - 1.2 8.2 4.1 2.4 7.2 2.8 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec23_trunk PF04811.10 KEZ44075.1 - 1.1e-52 178.8 0.0 7.1e-52 176.1 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEZ44075.1 - 1.1e-22 79.4 0.0 1.9e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEZ44075.1 - 5e-18 65.4 0.0 8.2e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEZ44075.1 - 5.4e-16 57.8 6.6 1.2e-15 56.8 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KEZ44075.1 - 3.7e-05 23.3 0.0 8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat tRNA-synt_2 PF00152.15 KEZ44076.1 - 1.4e-63 214.7 0.0 1.2e-62 211.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEZ44076.1 - 0.00035 20.3 0.0 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEZ44076.1 - 0.026 13.7 0.0 3.5 6.7 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) CorA PF01544.13 KEZ44077.1 - 1.1e-05 24.6 0.3 1.1e-05 24.6 0.2 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2899 PF11449.3 KEZ44077.1 - 0.028 13.6 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) HET PF06985.6 KEZ44078.1 - 9.7e-13 48.4 3.9 2.1e-12 47.3 2.7 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) XPG_N PF00752.12 KEZ44079.1 - 1.6e-32 111.7 0.0 1.6e-32 111.7 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 KEZ44079.1 - 5.1e-31 106.6 0.8 8.7e-31 105.8 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 KEZ44079.1 - 6.9e-06 26.2 0.1 4.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 KEZ44079.1 - 0.065 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Acyl-CoA_dh_1 PF00441.19 KEZ44080.1 - 1.6e-40 138.6 0.4 2.3e-40 138.1 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KEZ44080.1 - 1.2e-19 69.5 0.2 2.2e-19 68.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEZ44080.1 - 6.6e-19 68.5 0.0 1.8e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 KEZ44080.1 - 1e-18 66.8 0.1 1.8e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 KEZ44080.1 - 1.1e-07 32.1 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_60s PF00428.14 KEZ44080.1 - 0.14 12.6 10.7 0.29 11.5 7.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAP PF07174.6 KEZ44080.1 - 0.48 9.6 10.5 0.75 9.0 7.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Big_3_4 PF13754.1 KEZ44081.1 - 0.22 11.8 4.5 0.73 10.2 3.1 1.9 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Fungal_trans_2 PF11951.3 KEZ44082.1 - 1.9e-29 102.4 0.8 1.9e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ44082.1 - 1.3e-08 34.6 12.2 2.3e-08 33.8 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 KEZ44082.1 - 0.063 12.9 4.6 0.21 11.3 3.2 2.0 1 0 0 1 1 1 0 AT hook motif PDE6_gamma PF04868.7 KEZ44083.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit ABC_tran PF00005.22 KEZ44085.1 - 3.3e-53 179.6 0.0 2.7e-26 92.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KEZ44085.1 - 3.3e-32 111.3 32.9 5.9e-19 68.0 6.7 3.7 3 1 1 4 4 4 3 ABC-2 type transporter AAA_21 PF13304.1 KEZ44085.1 - 1.3e-18 67.9 1.2 0.0019 18.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_16 PF13191.1 KEZ44085.1 - 1.8e-10 41.0 0.8 0.00015 21.7 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 KEZ44085.1 - 3.9e-10 39.1 0.4 0.00016 20.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ44085.1 - 2e-09 37.6 0.1 0.0071 16.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEZ44085.1 - 4.3e-08 32.5 2.8 0.0034 16.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KEZ44085.1 - 6.3e-08 32.0 0.0 0.22 10.5 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_25 PF13481.1 KEZ44085.1 - 8.5e-08 31.8 3.8 0.003 16.9 0.0 3.7 5 0 0 5 5 3 2 AAA domain AAA_17 PF13207.1 KEZ44085.1 - 5.3e-07 30.4 2.5 0.01 16.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KEZ44085.1 - 5.6e-07 29.6 4.1 0.0011 18.9 0.2 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 KEZ44085.1 - 9.9e-07 28.5 0.0 0.022 14.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 KEZ44085.1 - 1.3e-06 27.8 7.4 0.0022 17.2 0.0 4.3 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 KEZ44085.1 - 1.3e-06 28.0 0.5 0.017 14.6 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_19 PF13245.1 KEZ44085.1 - 4.2e-06 26.4 1.1 0.008 15.9 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 KEZ44085.1 - 9e-06 26.0 0.8 0.058 13.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KEZ44085.1 - 9.6e-06 26.0 9.9 0.00096 19.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 KEZ44085.1 - 1.1e-05 25.1 0.8 0.033 13.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 KEZ44085.1 - 1.1e-05 25.0 5.0 0.026 13.9 0.1 3.7 5 0 0 5 5 3 2 AAA-like domain SbcCD_C PF13558.1 KEZ44085.1 - 1.9e-05 24.5 1.3 0.27 11.1 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit cobW PF02492.14 KEZ44085.1 - 8e-05 22.1 2.2 0.22 10.9 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KEZ44085.1 - 0.00018 21.2 3.0 0.08 12.6 0.0 2.7 3 0 0 3 3 2 2 Archaeal ATPase AAA_33 PF13671.1 KEZ44085.1 - 0.00019 21.3 0.2 0.46 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KEZ44085.1 - 0.00029 21.3 0.1 0.83 10.1 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 KEZ44085.1 - 0.00058 18.8 3.7 0.2 10.4 0.0 2.6 3 0 0 3 3 2 2 Type II/IV secretion system protein RNA_helicase PF00910.17 KEZ44085.1 - 0.00063 19.8 0.1 1.5 9.0 0.0 2.8 3 0 0 3 3 2 1 RNA helicase UPF0079 PF02367.12 KEZ44085.1 - 0.00066 19.2 0.4 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 KEZ44085.1 - 0.00085 19.0 0.2 0.65 9.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KEZ44085.1 - 0.001 18.9 1.7 0.79 9.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEZ44085.1 - 0.0019 17.7 0.2 0.85 9.1 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 KEZ44085.1 - 0.0022 17.7 0.7 3.1 7.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KEZ44085.1 - 0.0027 17.3 0.2 2.5 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEZ44085.1 - 0.0038 17.4 0.4 6.5 6.9 0.1 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KEZ44085.1 - 0.0067 15.8 0.7 1.1 8.7 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.1 KEZ44085.1 - 0.0067 16.3 0.1 6 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KEZ44085.1 - 0.0092 15.2 0.6 0.35 10.1 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein Septin PF00735.13 KEZ44085.1 - 0.0093 15.0 0.2 0.54 9.2 0.0 2.3 2 0 0 2 2 2 1 Septin ATP-synt_ab PF00006.20 KEZ44085.1 - 0.015 14.7 0.0 0.82 9.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 KEZ44085.1 - 0.015 14.7 0.2 5.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 KEZ44085.1 - 0.025 13.6 0.7 4.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 KEZ44085.1 - 0.025 14.2 0.7 4.2 7.0 0.1 3.7 4 0 0 4 4 4 0 NTPase KAP_NTPase PF07693.9 KEZ44085.1 - 0.038 12.9 0.0 3.8 6.4 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain PRK PF00485.13 KEZ44085.1 - 0.042 13.4 1.7 1.1 8.7 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.4 KEZ44085.1 - 0.044 12.3 1.6 0.61 8.5 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PhoH PF02562.11 KEZ44085.1 - 0.051 12.7 0.7 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein SRPRB PF09439.5 KEZ44085.1 - 0.063 12.4 0.6 8 5.6 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.17 KEZ44085.1 - 0.098 12.0 1.1 5.4 6.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 KEZ44085.1 - 0.1 11.5 0.0 6.3 5.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KEZ44085.1 - 0.13 11.4 0.7 20 4.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Vfa1 PF08432.5 KEZ44085.1 - 0.21 11.5 10.9 0.016 15.1 2.8 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Dynamin_N PF00350.18 KEZ44085.1 - 0.58 9.9 5.2 3.2 7.5 0.0 3.0 3 0 0 3 3 2 0 Dynamin family DUF87 PF01935.12 KEZ44085.1 - 8.7 6.0 9.4 0.65 9.7 0.3 3.3 5 0 0 5 5 3 0 Domain of unknown function DUF87 polyprenyl_synt PF00348.12 KEZ44086.1 - 2.8e-51 173.8 0.0 2.1e-48 164.4 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Vma12 PF11712.3 KEZ44087.1 - 7.6e-39 132.6 0.0 1.2e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase SCIMP PF15050.1 KEZ44087.1 - 3.1 7.7 6.1 22 4.9 0.3 2.9 2 1 0 2 2 2 0 SCIMP protein GMC_oxred_N PF00732.14 KEZ44088.1 - 2.5e-42 145.0 0.0 7.1e-42 143.5 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ44088.1 - 1.3e-22 80.6 0.0 4.9e-22 78.7 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ44088.1 - 9.4e-06 24.7 0.0 0.00019 20.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KEZ44088.1 - 0.0012 17.8 0.6 0.035 13.0 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ44088.1 - 0.0017 18.3 0.2 0.0047 16.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ44088.1 - 0.0023 17.9 0.0 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ44088.1 - 0.005 15.9 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KEZ44088.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 KEZ44088.1 - 0.051 13.5 0.2 0.37 10.8 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.9 KEZ44088.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ44088.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KEZ44088.1 - 0.31 9.4 0.0 0.45 8.9 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Zip PF02535.17 KEZ44089.1 - 2e-26 92.7 49.3 2.4e-11 43.2 5.5 4.2 2 1 2 4 4 4 3 ZIP Zinc transporter BAF1_ABF1 PF04684.8 KEZ44089.1 - 0.21 10.4 5.1 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Clp1 PF06807.9 KEZ44090.1 - 3e-10 40.1 0.0 2.2e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KEZ44090.1 - 0.0021 17.7 0.0 0.03 14.0 0.0 2.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KEZ44090.1 - 0.0036 18.1 0.0 0.0098 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ44090.1 - 0.0083 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KEZ44090.1 - 0.0086 15.9 0.0 0.076 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KEZ44090.1 - 0.0099 16.0 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KEZ44090.1 - 0.022 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KEZ44090.1 - 0.031 14.4 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KEZ44090.1 - 0.034 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ44090.1 - 0.047 13.2 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 KEZ44090.1 - 0.049 13.4 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Sigma54_activ_2 PF14532.1 KEZ44090.1 - 0.058 13.4 0.0 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 KEZ44090.1 - 0.096 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_polI_A34 PF08208.6 KEZ44091.1 - 7.8e-05 22.4 13.6 7.8e-05 22.4 9.4 5.7 2 2 2 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 PAP2 PF01569.16 KEZ44092.1 - 6e-15 55.0 5.8 6e-15 55.0 4.0 2.3 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 KEZ44092.1 - 5.3e-05 22.8 4.8 5.3e-05 22.8 3.3 2.4 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KEZ44092.1 - 0.74 10.1 5.9 1.7 8.9 0.8 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Pkinase PF00069.20 KEZ44093.1 - 7e-67 225.3 0.0 1.2e-66 224.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44093.1 - 1.4e-29 103.0 0.0 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 KEZ44093.1 - 7.3e-27 93.5 3.7 3.4e-10 40.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ44093.1 - 1.7e-18 65.3 5.3 2.5e-08 33.3 0.2 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KEZ44093.1 - 1.7e-17 63.0 1.9 3.6e-07 30.2 0.2 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ44093.1 - 7.4e-17 61.3 2.5 1.6e-07 31.6 0.0 4.2 2 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ44093.1 - 4.1e-12 45.0 0.6 0.00098 19.1 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Kinase-like PF14531.1 KEZ44093.1 - 6.2e-05 22.1 0.0 9.3e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ44093.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEZ44093.1 - 0.00063 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KEZ44093.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RRM_1 PF00076.17 KEZ44094.1 - 5e-11 42.0 0.0 8e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44094.1 - 3e-10 39.9 0.0 7.4e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44094.1 - 1.4e-08 34.4 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KEZ44094.1 - 0.1 12.3 0.1 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 APH PF01636.18 KEZ44095.1 - 7.2e-07 29.1 0.1 8.9e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEZ44095.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.3 1 1 0 1 1 1 0 Ecdysteroid kinase Glyco_hydro_18 PF00704.23 KEZ44096.1 - 3e-76 257.0 1.6 4.2e-76 256.6 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEZ44096.1 - 4.2e-09 36.2 19.1 4.2e-09 36.2 13.3 4.8 5 1 1 6 6 6 2 Chitin recognition protein LysM PF01476.15 KEZ44097.1 - 1.7e-26 91.7 0.0 4.9e-05 23.1 0.0 7.5 7 0 0 7 7 7 5 LysM domain UPF0203 PF05254.7 KEZ44097.1 - 0.04 13.7 0.1 46 3.9 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) NAD_binding_6 PF08030.7 KEZ44099.1 - 6e-16 58.7 0.0 9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KEZ44099.1 - 2.1e-12 47.2 19.4 5.2e-12 45.9 13.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEZ44099.1 - 2.4e-05 24.1 0.0 0.00052 19.8 0.0 2.8 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 KEZ44099.1 - 4.7e-05 23.9 0.0 0.0062 17.0 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain VanZ PF04892.7 KEZ44100.1 - 6.3e-15 55.2 3.2 9.4e-15 54.7 2.2 1.3 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 KEZ44100.1 - 0.0016 17.4 2.6 0.0022 17.0 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) MscS_TM PF12794.2 KEZ44100.1 - 0.0053 15.4 1.2 0.28 9.7 0.6 2.0 2 0 0 2 2 2 2 Mechanosensitive ion channel inner membrane domain 1 Asp-Al_Ex PF06826.7 KEZ44100.1 - 0.05 13.0 0.2 0.05 13.0 0.1 1.7 1 1 1 2 2 2 0 Predicted Permease Membrane Region Bromodomain PF00439.20 KEZ44101.1 - 5.4e-19 67.9 0.3 1.9e-18 66.1 0.2 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KEZ44101.1 - 1.9e-08 33.9 0.0 4.1e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Asp PF00026.18 KEZ44102.1 - 4.4e-111 371.1 0.0 5.3e-111 370.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ44102.1 - 1.2e-12 48.1 0.0 2.6e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEZ44102.1 - 6.1e-06 26.6 0.1 0.037 14.5 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KEZ44102.1 - 8.7e-06 25.3 0.0 9.9e-05 21.9 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KEZ44102.1 - 0.0032 17.2 0.0 7.2 6.5 0.0 3.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease OmpH PF03938.9 KEZ44103.1 - 0.0018 18.2 11.2 0.0092 15.9 7.4 2.3 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) TSA PF03249.8 KEZ44103.1 - 9.8 4.5 12.2 20 3.5 8.4 1.4 1 0 0 1 1 1 0 Type specific antigen Drc1-Sld2 PF11719.3 KEZ44105.1 - 2.2e-82 277.4 21.1 2.5e-82 277.2 14.6 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein Swi5 PF07061.6 KEZ44105.1 - 0.4 10.4 2.2 0.77 9.5 0.0 2.5 3 0 0 3 3 3 0 Swi5 DASH_Spc34 PF08657.5 KEZ44106.1 - 2.7e-51 174.7 0.7 2e-50 171.9 0.5 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 DASH_Spc19 PF08287.6 KEZ44106.1 - 0.037 13.6 3.9 0.056 13.0 2.7 1.2 1 0 0 1 1 1 0 Spc19 IncA PF04156.9 KEZ44106.1 - 0.086 12.4 4.8 0.24 10.9 3.4 1.6 1 1 0 1 1 1 0 IncA protein Pkinase PF00069.20 KEZ44107.1 - 3.1e-12 46.1 0.0 1.8e-11 43.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44107.1 - 2.3e-11 43.2 0.0 2.7e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase TFIID_20kDa PF03847.8 KEZ44108.1 - 4.5e-19 68.4 0.1 8e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Rpn3_C PF08375.6 KEZ44110.1 - 8e-25 87.0 1.3 2.2e-24 85.6 0.9 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KEZ44110.1 - 1.4e-21 76.7 0.9 6.9e-21 74.5 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 KEZ44110.1 - 0.031 14.1 0.1 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 KEZ44110.1 - 0.12 12.0 0.1 0.65 9.7 0.1 2.1 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 MOZ_SAS PF01853.13 KEZ44111.1 - 1.2e-47 161.6 0.0 3e-47 160.3 0.0 1.6 2 0 0 2 2 2 1 MOZ/SAS family Macoilin PF09726.4 KEZ44111.1 - 0.017 13.4 0.3 0.025 12.9 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein ATP-synt_C PF00137.16 KEZ44112.1 - 3.4e-16 58.8 10.7 6.7e-16 57.9 7.4 1.5 1 0 0 1 1 1 1 ATP synthase subunit C RINT1_TIP1 PF04437.8 KEZ44114.1 - 1.5e-92 310.7 0.0 2.3e-92 310.0 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Zwint PF15556.1 KEZ44114.1 - 0.00033 20.0 6.2 0.0054 16.0 4.9 2.3 2 0 0 2 2 2 1 ZW10 interactor DUF4164 PF13747.1 KEZ44114.1 - 0.014 15.4 8.4 0.054 13.6 4.4 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1664 PF07889.7 KEZ44114.1 - 0.024 14.4 1.2 0.1 12.4 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.6 KEZ44114.1 - 0.17 11.7 6.1 0.58 10.0 1.9 2.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mito_carr PF00153.22 KEZ44115.1 - 3.8e-63 209.2 2.6 1.7e-21 75.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_trans_2_3 PF13632.1 KEZ44116.1 - 5.8e-45 153.3 4.4 5.8e-45 153.3 3.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ44116.1 - 1.9e-09 37.7 0.1 6.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KEZ44116.1 - 1.8e-07 30.9 0.1 1.7e-05 24.5 0.0 2.9 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KEZ44116.1 - 1.2e-05 24.6 0.1 5.9e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Peptidase_C48 PF02902.14 KEZ44117.1 - 3.2e-31 108.6 0.0 7.6e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Proteasome PF00227.21 KEZ44118.1 - 2.2e-34 118.4 0.0 2.7e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit AMP-binding PF00501.23 KEZ44119.1 - 1e-17 63.6 0.0 8.3e-10 37.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Lysine_decarbox PF03641.9 KEZ44120.1 - 1.8e-27 95.7 0.0 3.4e-27 94.8 0.0 1.5 1 1 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 KEZ44121.1 - 7.3e-47 159.1 0.1 9.6e-47 158.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KEZ44121.1 - 1.8e-11 43.1 0.3 3e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 KEZ44122.1 - 9.2e-48 160.9 6.6 1e-47 160.8 4.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TRAPPC9-Trs120 PF08626.6 KEZ44123.1 - 5.4e-137 457.9 0.0 1.6e-136 456.4 0.0 1.7 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.20 KEZ44124.1 - 9.5e-09 35.3 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ44124.1 - 1.8e-08 34.4 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ44124.1 - 0.025 14.2 0.0 0.055 13.1 0.0 1.6 1 1 0 1 1 1 0 KR domain DUF904 PF06005.7 KEZ44124.1 - 0.029 14.6 0.4 0.083 13.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Sugar_tr PF00083.19 KEZ44125.1 - 3.8e-106 355.3 19.9 4.9e-106 355.0 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ44125.1 - 3e-18 65.6 24.1 3e-18 65.6 16.7 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2264 PF10022.4 KEZ44126.1 - 1.8e-127 424.9 0.1 2.2e-127 424.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) LysM PF01476.15 KEZ44126.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 LysM domain Glyco_hydro_63 PF03200.11 KEZ44127.1 - 2.9e-238 792.7 0.0 3.1e-237 789.3 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KEZ44127.1 - 1.5e-05 23.8 0.1 3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Trehalase GTPase_Cys_C PF12631.2 KEZ44128.1 - 5.3e-21 74.7 0.1 3.9e-20 72.0 0.0 2.2 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KEZ44128.1 - 7.2e-18 64.6 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ44128.1 - 5e-07 29.1 0.0 5.8e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KEZ44128.1 - 2.6e-06 27.3 0.0 1e-05 25.4 0.0 1.9 2 1 0 2 2 2 1 Dynamin family TrmE_N PF10396.4 KEZ44128.1 - 1.6e-05 24.8 0.1 4.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTP_EFTU PF00009.22 KEZ44128.1 - 0.00038 19.9 0.0 0.091 12.1 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 KEZ44128.1 - 0.0029 18.1 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KEZ44128.1 - 0.02 14.0 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KEZ44128.1 - 0.032 14.5 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Ras PF00071.17 KEZ44128.1 - 0.069 12.5 0.0 0.88 8.9 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_28 PF13521.1 KEZ44128.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KEZ44128.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L28e PF01778.12 KEZ44129.1 - 3.6e-33 114.4 2.5 3.6e-33 114.4 1.7 2.1 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KEZ44129.1 - 2.5e-25 88.4 13.0 2.5e-25 88.4 9.0 2.7 3 0 0 3 3 3 1 Mak16 protein C-terminal region TFIIF_alpha PF05793.7 KEZ44129.1 - 0.021 13.2 36.1 0.03 12.6 25.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.6 KEZ44129.1 - 0.032 12.6 14.2 0.041 12.2 9.9 1.2 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.7 KEZ44129.1 - 0.076 10.9 38.6 0.11 10.4 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 KEZ44129.1 - 0.084 12.9 19.6 0.2 11.6 13.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 KEZ44129.1 - 0.54 9.4 30.5 0.81 8.9 21.1 1.3 1 0 0 1 1 1 0 SDA1 Herpes_DNAp_acc PF04929.7 KEZ44129.1 - 1.1 8.1 5.2 1.6 7.5 3.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF1675 PF07897.6 KEZ44129.1 - 2.9 7.6 11.2 4.3 7.1 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RNase_H2-Ydr279 PF09468.5 KEZ44129.1 - 3.3 6.8 10.4 7 5.7 7.2 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 KEZ44129.1 - 5.8 4.8 25.4 9.5 4.1 17.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RabGAP-TBC PF00566.13 KEZ44130.1 - 3.4e-34 118.2 3.8 8.4e-34 116.9 2.6 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 KEZ44130.1 - 2.2e-10 40.2 0.0 0.00036 19.8 0.0 3.8 3 1 1 4 4 4 3 Domain of unknown function (DUF3548) adh_short_C2 PF13561.1 KEZ44131.1 - 2.5e-19 69.9 0.0 3.1e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ44131.1 - 8.5e-18 64.8 0.0 1.9e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ44131.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Med6 PF04934.9 KEZ44132.1 - 2.7e-41 140.4 0.0 3.3e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Pkinase PF00069.20 KEZ44134.1 - 6.2e-37 127.1 0.0 1.1e-31 109.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44134.1 - 5.8e-17 61.6 0.0 1.1e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ44134.1 - 0.0074 16.0 0.1 0.038 13.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.18 KEZ44135.1 - 2.5e-17 63.6 0.3 4.3e-17 62.8 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Luciferase_cat PF10285.4 KEZ44135.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain YbgT_YccB PF08173.6 KEZ44135.1 - 0.16 11.8 2.9 0.15 11.9 0.3 2.2 2 0 0 2 2 2 0 Membrane bound YbgT-like protein WD40 PF00400.27 KEZ44136.1 - 7.5e-63 206.3 19.7 4.8e-13 48.4 0.1 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KEZ44136.1 - 2.1e-08 32.7 1.4 0.0019 16.4 0.3 4.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KEZ44136.1 - 1.3e-06 27.4 0.3 0.0096 14.7 0.0 3.8 2 1 1 4 4 4 2 Nup133 N terminal like DUF1513 PF07433.6 KEZ44136.1 - 0.00044 19.2 0.9 4.2 6.1 0.0 3.8 2 1 2 4 4 4 2 Protein of unknown function (DUF1513) Apc4_WD40 PF12894.2 KEZ44136.1 - 0.009 15.5 0.0 2.7 7.5 0.0 3.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 KEZ44136.1 - 0.01 13.6 0.0 0.047 11.5 0.0 1.9 1 1 1 2 2 2 0 IKI3 family DUF3312 PF11768.3 KEZ44136.1 - 0.2 9.8 0.0 3.2 5.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) zf-UBR PF02207.15 KEZ44137.1 - 2.1e-17 62.6 14.7 5.3e-17 61.2 10.2 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KEZ44137.1 - 8.6e-07 28.5 0.1 2.7e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4_2 PF13923.1 KEZ44137.1 - 0.019 14.9 0.6 0.019 14.9 0.4 4.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) UCR_UQCRX_QCR9 PF05365.7 KEZ44138.1 - 1.3e-20 72.7 1.6 2.3e-20 71.9 1.1 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like EVC2_like PF12297.3 KEZ44138.1 - 0.18 10.4 0.2 0.39 9.2 0.0 1.6 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Vpu PF00558.14 KEZ44138.1 - 2.9 7.5 4.7 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Vpu protein E1-E2_ATPase PF00122.15 KEZ44139.1 - 4e-59 199.4 1.3 4e-59 199.4 0.9 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ44139.1 - 5.6e-46 156.3 5.0 9.4e-45 152.3 1.1 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ44139.1 - 4.9e-26 92.4 0.2 1.9e-25 90.5 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ44139.1 - 4.4e-21 74.6 0.0 1.1e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ44139.1 - 2.3e-14 54.0 0.0 4.5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ44139.1 - 3.1e-09 36.1 0.0 1.5e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEZ44139.1 - 2.3e-06 27.3 0.6 0.00011 21.9 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KEZ44139.1 - 0.0042 16.9 0.1 0.069 13.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) YjgP_YjgQ PF03739.9 KEZ44139.1 - 0.0068 15.1 1.0 0.013 14.2 0.3 1.7 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family RWD PF05773.17 KEZ44140.1 - 4.8e-23 81.1 0.2 8.5e-23 80.4 0.2 1.3 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 KEZ44140.1 - 0.0019 17.6 0.1 0.004 16.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UPF0564 PF10595.4 KEZ44140.1 - 0.0031 16.4 1.7 0.004 16.1 1.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 HTH_32 PF13565.1 KEZ44140.1 - 0.27 12.0 1.9 0.78 10.5 0.5 2.3 2 1 0 2 2 2 0 Homeodomain-like domain Lum_binding PF00677.12 KEZ44141.1 - 6.1e-36 122.1 0.1 1e-17 63.7 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ATP-synt_DE_N PF02823.11 KEZ44141.1 - 0.0091 15.7 0.0 0.028 14.1 0.0 1.9 1 1 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain PGM_PMM_I PF02878.11 KEZ44142.1 - 2.3e-17 62.7 0.3 8.5e-08 31.7 0.0 3.6 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KEZ44142.1 - 1.9e-12 47.4 0.0 8.8e-12 45.2 0.0 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KEZ44142.1 - 1.3e-10 41.0 0.2 3.8e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KEZ44142.1 - 0.0091 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_31 PF13847.1 KEZ44143.1 - 9.6e-12 44.7 0.2 1.9e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KEZ44143.1 - 4.6e-10 39.1 0.0 6.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KEZ44143.1 - 4e-09 37.0 0.0 9.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ44143.1 - 9.7e-09 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KEZ44143.1 - 4.8e-08 32.3 0.0 8.1e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 KEZ44143.1 - 1.1e-07 32.2 0.0 3.8e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 KEZ44143.1 - 2.5e-06 26.4 0.1 3.7e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 KEZ44143.1 - 8.3e-06 26.1 0.0 3.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44143.1 - 2.5e-05 24.6 0.0 5.7e-05 23.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ44143.1 - 0.00012 21.7 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ44143.1 - 0.00015 21.1 0.6 0.00064 19.1 0.1 1.9 1 1 1 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 KEZ44143.1 - 0.0018 17.3 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 KEZ44143.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KEZ44144.1 - 1.3e-59 201.4 0.0 9.8e-38 129.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44144.1 - 3.3e-28 98.4 0.0 2.9e-20 72.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KEZ44144.1 - 2e-13 50.3 0.0 3.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KEZ44144.1 - 1.2e-06 27.7 0.0 0.00026 20.0 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KEZ44144.1 - 1.5e-05 24.8 0.0 0.033 13.9 0.2 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 KEZ44144.1 - 0.0058 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain Seadorna_VP7 PF07387.6 KEZ44144.1 - 0.1 11.4 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KEZ44144.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 KEZ44144.1 - 0.18 11.5 0.0 0.51 10.1 0.0 1.8 1 0 0 1 1 1 0 PAS fold Pkinase_C PF00433.19 KEZ44144.1 - 1.2 9.7 6.4 0.22 12.0 0.1 3.2 3 0 0 3 3 3 0 Protein kinase C terminal domain Acyltransferase PF01553.16 KEZ44145.1 - 7.6e-13 48.0 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase PAP1 PF08601.5 KEZ44146.1 - 0.0027 17.4 5.3 0.54 9.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor PAP1 Peptidase_S21 PF00716.12 KEZ44146.1 - 0.0037 16.6 0.6 0.0052 16.1 0.4 1.1 1 0 0 1 1 1 1 Assemblin (Peptidase family S21) DUF904 PF06005.7 KEZ44146.1 - 0.0044 17.2 0.1 0.0091 16.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) TSC22 PF01166.13 KEZ44146.1 - 0.013 15.3 0.2 0.038 13.9 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.16 KEZ44146.1 - 2.4 8.1 5.6 8.3 6.4 3.9 1.8 1 1 0 1 1 1 0 bZIP transcription factor eIF-3_zeta PF05091.7 KEZ44147.1 - 2.7e-194 646.5 0.0 3.3e-194 646.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 KEZ44147.1 - 0.097 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF569) DUF2529 PF10740.4 KEZ44147.1 - 0.18 11.2 0.0 0.87 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2529) KH_1 PF00013.24 KEZ44148.1 - 3e-05 23.5 1.0 6.9e-05 22.4 0.7 1.5 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 KEZ44149.1 - 5e-133 444.2 0.0 1.5e-132 442.6 0.0 1.6 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins HET PF06985.6 KEZ44150.1 - 1.2e-23 83.8 0.4 2e-23 83.1 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.1 KEZ44152.1 - 2.7e-14 52.6 8.9 5e-08 32.8 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ44152.1 - 1.6e-12 46.9 13.5 7.7e-06 25.9 1.6 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ44152.1 - 7.2e-11 41.6 13.1 3.7e-05 23.7 1.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ44152.1 - 1.3e-07 31.5 2.6 0.029 14.5 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ44152.1 - 2.5e-05 24.3 3.8 0.013 15.6 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 KEZ44152.1 - 0.07 13.4 0.5 0.15 12.3 0.3 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain LIM PF00412.17 KEZ44152.1 - 0.81 9.7 3.7 5.7 7.0 2.6 2.1 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 KEZ44152.1 - 2.4 8.2 10.2 11 6.1 0.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger AOX PF01786.12 KEZ44153.1 - 4.9e-69 231.8 0.0 5.9e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase RhodobacterPufX PF11511.3 KEZ44154.1 - 0.098 12.0 0.2 0.098 12.0 0.1 2.4 2 0 0 2 2 2 0 Intrinsic membrane protein PufX eIF3_subunit PF08597.5 KEZ44155.1 - 4e-69 232.9 22.3 4.4e-69 232.7 15.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Per1 PF04080.8 KEZ44157.1 - 5.8e-101 337.4 9.6 7.3e-101 337.0 6.6 1.1 1 0 0 1 1 1 1 Per1-like HLH PF00010.21 KEZ44159.1 - 2.8e-13 49.3 0.4 5.6e-13 48.3 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.4 KEZ44159.1 - 7.4 5.0 16.8 11 4.5 11.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Aldedh PF00171.17 KEZ44160.1 - 1.3e-112 376.5 0.0 1.6e-112 376.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoD PF09423.5 KEZ44161.1 - 9.6e-08 31.0 0.0 3.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Ank_2 PF12796.2 KEZ44162.1 - 6.2e-51 170.6 0.4 1.9e-15 56.9 0.0 8.7 4 2 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ44162.1 - 1.2e-40 135.2 8.7 1.6e-07 30.7 0.0 13.5 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.1 KEZ44162.1 - 8.6e-35 118.5 5.0 1.6e-05 25.2 0.0 11.2 8 3 3 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ44162.1 - 1.6e-34 114.4 5.2 0.00064 19.7 0.0 13.5 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.1 KEZ44162.1 - 1e-28 98.6 8.6 7.2e-06 26.0 0.1 8.9 9 1 2 11 11 11 8 Ankyrin repeats (many copies) YqfQ PF14181.1 KEZ44162.1 - 2.5 8.1 11.7 7.7 6.5 8.1 1.8 1 0 0 1 1 1 0 YqfQ-like protein CFEM PF05730.6 KEZ44163.1 - 9.2e-13 47.8 13.7 1.4e-12 47.2 9.5 1.3 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 KEZ44163.1 - 1.5 8.9 10.1 2.7 8.1 7.0 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain MFS_1 PF07690.11 KEZ44164.1 - 4.1e-32 111.2 31.0 4.1e-32 111.2 21.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ44164.1 - 9.2e-08 31.0 14.4 9.2e-08 31.0 10.0 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter DUF4131 PF13567.1 KEZ44164.1 - 2.6 7.4 15.2 4.9 6.5 0.2 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) DUF1772 PF08592.6 KEZ44165.1 - 0.05 13.3 7.5 0.12 12.0 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Runt PF00853.14 KEZ44165.1 - 0.078 12.4 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Runt domain adh_short PF00106.20 KEZ44166.1 - 2.8e-22 79.4 1.3 3.7e-22 79.0 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ44166.1 - 3.2e-19 69.6 0.0 4.2e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ44166.1 - 6.1e-08 32.5 1.1 3.1e-07 30.2 0.7 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEZ44166.1 - 0.0034 16.3 0.1 0.0047 15.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Queuosine_synth PF02547.10 KEZ44166.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein TRP PF06011.7 KEZ44167.1 - 3.3e-86 289.5 16.4 1.5e-85 287.4 11.4 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KEZ44167.1 - 2.1e-20 73.2 0.1 3.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain PWI PF01480.12 KEZ44168.1 - 2.3e-29 101.3 0.0 6.6e-29 99.8 0.0 1.8 2 0 0 2 2 2 1 PWI domain DNA_mis_repair PF01119.14 KEZ44168.1 - 8.5e-14 51.0 0.0 1.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KEZ44168.1 - 0.04 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PDZ_2 PF13180.1 KEZ44169.1 - 1.4e-05 24.8 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KEZ44169.1 - 6.3e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 KEZ44170.1 - 8.1e-49 165.1 0.0 9.9e-49 164.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ44170.1 - 7.5e-15 55.4 0.0 1.5e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ44170.1 - 4.8e-10 38.9 0.0 6.4e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KEZ44170.1 - 0.00047 20.3 0.1 0.0038 17.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KEZ44170.1 - 0.005 16.0 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KEZ44170.1 - 0.027 13.7 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 KEZ44170.1 - 0.076 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 KEZ44170.1 - 0.079 11.6 1.8 1 7.9 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.1 KEZ44170.1 - 0.09 12.9 0.4 0.52 10.4 0.1 2.1 2 1 0 3 3 3 0 AAA domain Peptidase_S10 PF00450.17 KEZ44171.1 - 1.2e-52 179.5 0.0 1e-50 173.1 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase Homeobox PF00046.24 KEZ44172.1 - 1.7e-12 46.7 0.5 1.7e-12 46.7 0.3 1.8 2 0 0 2 2 2 1 Homeobox domain NAD_kinase PF01513.16 KEZ44173.1 - 3.5e-70 236.0 0.0 4.9e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 KEZ44174.1 - 0.00021 21.6 0.0 0.00056 20.2 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 TPR_5 PF12688.2 KEZ44174.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Tetratrico peptide repeat RNase_PH_C PF03725.10 KEZ44174.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MaoC_dehydratas PF01575.14 KEZ44175.1 - 6.1e-22 77.2 0.0 1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KEZ44175.1 - 4.2e-07 29.8 0.0 0.00014 21.6 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase dCMP_cyt_deam_1 PF00383.17 KEZ44176.1 - 1.1e-09 37.8 0.5 7.6e-08 31.9 0.3 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KEZ44176.1 - 0.00083 18.7 2.3 0.035 13.4 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sugar_tr PF00083.19 KEZ44177.1 - 1.7e-95 320.2 32.1 2.2e-95 319.8 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ44177.1 - 7.8e-20 70.8 37.0 9.9e-20 70.5 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HisG PF01634.13 KEZ44178.1 - 1.6e-47 161.1 0.2 9.8e-38 129.2 0.0 2.3 1 1 0 2 2 2 2 ATP phosphoribosyltransferase HisG_C PF08029.6 KEZ44178.1 - 2e-29 101.3 0.7 4.3e-29 100.2 0.5 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KEZ44178.1 - 0.11 12.0 0.0 4 6.9 0.0 2.5 2 1 0 2 2 2 0 NMT1/THI5 like STT3 PF02516.9 KEZ44180.1 - 1.5e-129 433.1 36.7 1.5e-124 416.6 24.2 2.3 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Herpes_gE PF02480.11 KEZ44180.1 - 0.26 9.4 0.3 0.63 8.2 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E ATP-synt_E PF05680.7 KEZ44181.1 - 4.5e-23 81.0 0.1 4.7e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 KEZ44181.1 - 0.048 13.8 0.4 0.066 13.3 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) WD40 PF00400.27 KEZ44182.1 - 2e-19 68.6 5.1 4.3e-08 32.7 0.2 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec20 PF03908.8 KEZ44182.1 - 0.29 10.8 1.8 2.5 7.8 0.9 2.2 1 1 1 2 2 2 0 Sec20 DUF3008 PF11450.3 KEZ44182.1 - 8.3 6.6 6.8 18 5.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknwon function (DUF3008) DUF726 PF05277.7 KEZ44183.1 - 2.4e-127 424.5 1.8 3.4e-127 424.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SKG6 PF08693.5 KEZ44184.1 - 0.0066 15.7 2.0 0.015 14.5 1.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain IncA PF04156.9 KEZ44184.1 - 0.02 14.5 0.7 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 IncA protein DUF1772 PF08592.6 KEZ44184.1 - 0.034 13.8 0.1 0.09 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) VSP PF03302.8 KEZ44184.1 - 0.083 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein VPEP PF07589.6 KEZ44184.1 - 1.1 9.2 5.7 3.5 7.6 4.0 2.0 1 0 0 1 1 1 0 PEP-CTERM motif DUF846 PF05832.7 KEZ44185.1 - 7.6e-41 139.1 4.4 9e-41 138.8 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Spore_III_AE PF09546.5 KEZ44185.1 - 0.0084 15.1 0.5 0.0099 14.8 0.3 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AE (spore_III_AE) DUF4173 PF13777.1 KEZ44185.1 - 0.025 13.8 2.6 0.032 13.5 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) DUF4191 PF13829.1 KEZ44185.1 - 0.044 12.8 1.0 0.061 12.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tic20 PF09685.5 KEZ44185.1 - 0.11 12.5 3.7 0.16 11.9 2.6 1.2 1 0 0 1 1 1 0 Tic20-like protein HpcH_HpaI PF03328.9 KEZ44186.1 - 6.6e-41 139.6 0.0 8.2e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KEZ44186.1 - 5.5e-16 58.3 0.0 1e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 KEZ44186.1 - 0.075 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain RRM_1 PF00076.17 KEZ44188.1 - 4.2e-24 83.9 0.0 5.4e-24 83.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44188.1 - 1.8e-16 59.8 0.0 2.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44188.1 - 7.1e-11 41.7 0.0 9.6e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1877 PF08974.5 KEZ44188.1 - 0.087 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) ChaC PF04752.7 KEZ44189.1 - 7e-36 123.8 0.0 9.2e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein EF-hand_1 PF00036.27 KEZ44190.1 - 3.2e-27 91.7 3.8 1.1e-06 27.5 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 KEZ44190.1 - 1.9e-25 88.7 1.1 5.9e-10 39.1 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 KEZ44190.1 - 1.1e-21 74.6 4.5 0.00071 19.2 0.3 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 KEZ44190.1 - 6.8e-21 73.6 7.3 1e-10 41.0 0.0 4.7 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 KEZ44190.1 - 1.4e-18 65.2 4.0 0.00045 19.4 0.0 4.6 4 0 0 4 4 4 4 EF hand Hep_59 PF07052.6 KEZ44192.1 - 1.7e-13 50.8 1.6 4.5e-13 49.4 0.0 2.5 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 SAF_2 PF13144.1 KEZ44192.1 - 0.05 13.0 0.1 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 SAF-like WD40 PF00400.27 KEZ44194.1 - 4.8e-27 92.8 8.6 5.5e-07 29.2 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KEZ44194.1 - 0.00018 20.3 0.2 0.48 9.1 0.0 3.0 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 KEZ44194.1 - 0.00045 18.4 1.5 0.0035 15.5 0.5 2.5 1 1 0 2 2 2 1 Nucleoporin Nup120/160 NST1 PF13945.1 KEZ44194.1 - 0.062 13.3 10.2 1 9.3 0.7 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Cys_Met_Meta_PP PF01053.15 KEZ44195.1 - 1.8e-59 200.9 0.0 3.8e-59 199.9 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2417 PF10329.4 KEZ44197.1 - 2.9e-75 252.6 1.5 3.8e-75 252.2 1.0 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KEZ44197.1 - 8.7e-05 22.5 3.4 0.00019 21.3 2.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family RhoGAP PF00620.22 KEZ44198.1 - 1.6e-35 121.9 0.0 4.4e-35 120.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KEZ44198.1 - 2.9e-31 107.3 39.0 7.1e-13 48.4 4.9 4.9 5 0 0 5 5 5 4 LIM domain 3Beta_HSD PF01073.14 KEZ44199.1 - 7.6e-65 218.3 0.0 9.1e-65 218.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ44199.1 - 3.8e-33 114.9 0.5 7.9e-33 113.8 0.3 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEZ44199.1 - 5.1e-19 68.2 0.1 7.5e-19 67.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KEZ44199.1 - 2.5e-13 49.5 3.3 1.1e-11 44.0 0.2 2.1 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KEZ44199.1 - 8.2e-13 48.7 0.2 1.1e-12 48.3 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KEZ44199.1 - 1e-07 31.1 2.9 3.3e-07 29.5 1.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KEZ44199.1 - 1.4e-05 25.0 1.5 7.1e-05 22.7 1.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ44199.1 - 0.0025 17.5 5.1 0.14 11.8 2.6 3.0 1 1 1 2 2 2 1 KR domain NmrA PF05368.8 KEZ44199.1 - 0.0075 15.5 1.6 0.012 14.8 0.5 1.9 2 1 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 KEZ44199.1 - 0.019 14.8 0.2 0.57 10.1 0.1 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF3798 PF12683.2 KEZ44199.1 - 0.028 13.5 0.2 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Ldh_1_N PF00056.18 KEZ44199.1 - 0.054 13.3 0.9 0.24 11.1 0.2 2.3 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain HMG_box PF00505.14 KEZ44200.1 - 8e-11 42.0 0.3 8e-11 42.0 0.2 2.8 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEZ44200.1 - 8.8e-08 32.4 0.6 8.8e-08 32.4 0.4 2.9 3 0 0 3 3 3 1 HMG-box domain Nnf1 PF03980.9 KEZ44200.1 - 0.041 13.8 0.1 0.041 13.8 0.1 1.7 2 0 0 2 2 2 0 Nnf1 Proteasome PF00227.21 KEZ44201.1 - 3.7e-26 91.5 0.0 4.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SIS PF01380.17 KEZ44202.1 - 6.3e-55 184.3 0.1 1.9e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KEZ44202.1 - 2.6e-27 95.5 0.0 3.2e-18 65.5 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KEZ44202.1 - 9.8e-20 70.8 0.0 2.2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KEZ44202.1 - 3.7e-11 42.8 0.0 7.8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KEZ44202.1 - 2.1e-06 26.6 0.0 3.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA PF00004.24 KEZ44203.1 - 4e-43 146.7 0.0 8.8e-43 145.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ44203.1 - 3.4e-08 33.6 0.4 2.4e-06 27.6 0.0 3.0 3 1 1 4 4 3 1 AAA ATPase domain AAA_5 PF07728.9 KEZ44203.1 - 1.4e-06 28.0 0.1 3.7e-05 23.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEZ44203.1 - 2.5e-06 27.6 0.0 0.001 19.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KEZ44203.1 - 3.2e-06 27.1 0.0 7.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KEZ44203.1 - 7.1e-06 25.2 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEZ44203.1 - 0.00032 20.4 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KEZ44203.1 - 0.00051 19.0 0.0 0.0011 17.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEZ44203.1 - 0.00067 20.4 1.1 0.0021 18.8 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEZ44203.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEZ44203.1 - 0.0017 17.1 0.0 0.0032 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KEZ44203.1 - 0.0017 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEZ44203.1 - 0.002 17.5 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KEZ44203.1 - 0.0025 18.1 0.1 0.0081 16.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 KEZ44203.1 - 0.0044 16.2 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEZ44203.1 - 0.0045 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 KEZ44203.1 - 0.005 16.9 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.6 KEZ44203.1 - 0.0071 15.9 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEZ44203.1 - 0.0075 15.7 0.0 0.026 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 KEZ44203.1 - 0.013 14.8 0.5 0.074 12.4 0.1 2.2 2 1 1 3 3 2 0 AAA domain Arch_ATPase PF01637.13 KEZ44203.1 - 0.018 14.7 0.1 0.098 12.3 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KEZ44203.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEZ44203.1 - 0.019 14.8 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KEZ44203.1 - 0.023 14.2 0.2 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KEZ44203.1 - 0.024 13.7 0.4 0.12 11.4 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 KEZ44203.1 - 0.025 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF4200 PF13863.1 KEZ44203.1 - 0.027 14.4 1.8 0.027 14.4 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ResIII PF04851.10 KEZ44203.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KEZ44203.1 - 0.031 13.4 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KEZ44203.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 KEZ44203.1 - 0.046 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KEZ44203.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KEZ44203.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 KEZ44203.1 - 0.18 12.1 4.9 2.5 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain KAR9 PF08580.5 KEZ44204.1 - 1.4e-136 456.5 2.7 1.4e-136 456.5 1.8 2.1 2 0 0 2 2 2 1 Yeast cortical protein KAR9 RNA_polI_A34 PF08208.6 KEZ44204.1 - 0.03 13.9 0.2 0.062 12.9 0.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NPV_P10 PF05531.7 KEZ44204.1 - 0.092 13.0 5.4 4.2 7.6 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 KEZ44204.1 - 0.13 12.6 10.8 0.59 10.5 0.7 4.3 3 1 1 4 4 4 0 Syntaxin 6, N-terminal APG17 PF04108.7 KEZ44204.1 - 0.36 9.5 1.7 0.5 9.1 0.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg17 DEAD PF00270.24 KEZ44205.1 - 3e-19 69.1 0.0 7.9e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ44205.1 - 1.5e-18 66.3 0.0 1.1e-17 63.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 KEZ44205.1 - 7.1e-11 41.7 0.3 7.1e-10 38.5 0.1 2.7 3 1 0 3 3 3 1 RQC domain HRDC PF00570.18 KEZ44205.1 - 1.5e-05 24.6 0.2 6.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 HRDC domain ResIII PF04851.10 KEZ44205.1 - 0.00096 19.0 0.0 0.0029 17.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KEZ44205.1 - 0.0011 17.8 0.1 0.0025 16.6 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Spc7 PF08317.6 KEZ44205.1 - 0.12 10.9 2.7 0.2 10.2 1.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2673 PF10880.3 KEZ44205.1 - 0.32 11.0 1.2 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) IncA PF04156.9 KEZ44205.1 - 0.8 9.2 4.5 1.8 8.1 3.1 1.6 1 0 0 1 1 1 0 IncA protein GPI-anchored PF10342.4 KEZ44206.1 - 1.2e-19 70.5 0.0 2.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KEZ44206.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ABM PF03992.11 KEZ44207.1 - 2.7e-06 27.3 0.1 0.00048 20.1 0.1 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase HCV_NS4a PF01006.15 KEZ44207.1 - 0.064 12.8 1.5 0.065 12.7 0.2 1.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a DUF4188 PF13826.1 KEZ44207.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) KH_1 PF00013.24 KEZ44208.1 - 1.2e-40 136.9 5.6 1.5e-16 59.7 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KEZ44208.1 - 5.3e-31 105.7 11.8 7.3e-12 44.6 1.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KEZ44208.1 - 2e-12 46.4 3.9 0.003 17.0 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KEZ44208.1 - 0.00012 21.6 0.8 0.62 9.7 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KEZ44208.1 - 0.001 18.8 6.2 0.45 10.3 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KEZ44209.1 - 1.9e-43 147.0 0.0 2.5e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.7 KEZ44210.1 - 2e-13 50.1 0.0 2.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KEZ44210.1 - 1.2e-10 40.9 0.4 3.2e-09 36.3 0.3 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PCNA_N PF00705.13 KEZ44211.1 - 8.4e-54 180.4 7.6 9e-54 180.3 4.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KEZ44211.1 - 6.3e-51 171.6 0.0 1.2e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KEZ44211.1 - 5.3e-12 45.3 0.1 6.2e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KEZ44211.1 - 1.5e-08 33.7 0.5 8.6e-07 27.9 0.4 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 KEZ44211.1 - 6e-06 25.4 0.4 4.3e-05 22.5 0.1 2.2 1 1 1 2 2 2 1 Hus1-like protein p450 PF00067.17 KEZ44212.1 - 6.3e-75 252.4 0.0 9.5e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CENP-K PF11802.3 KEZ44213.1 - 2.2e-08 33.6 3.4 0.0023 17.1 0.0 2.6 2 1 0 2 2 2 2 Centromere-associated protein K IncA PF04156.9 KEZ44213.1 - 0.00029 20.4 7.0 0.00029 20.4 4.8 2.6 3 0 0 3 3 3 1 IncA protein Ribosomal_S6e PF01092.14 KEZ44213.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S6e DivIC PF04977.10 KEZ44213.1 - 0.27 10.7 16.7 0.071 12.6 4.1 3.1 2 1 1 3 3 3 0 Septum formation initiator Sec8_exocyst PF04048.9 KEZ44213.1 - 0.64 9.6 6.7 1.1 8.8 1.3 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF724 PF05266.9 KEZ44213.1 - 0.96 9.0 10.9 2.9 7.4 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TBPIP PF07106.8 KEZ44213.1 - 1.4 8.4 14.8 0.26 10.8 0.4 2.9 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 KEZ44213.1 - 1.9 8.3 18.7 1 9.2 0.3 3.9 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 KEZ44213.1 - 1.9 8.1 12.7 0.36 10.4 0.4 3.4 2 1 2 4 4 4 0 Prefoldin subunit DUF342 PF03961.8 KEZ44213.1 - 2.6 6.3 9.5 1.1 7.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF342) FlxA PF14282.1 KEZ44213.1 - 6.7 6.7 14.3 0.63 10.0 0.3 2.8 2 1 0 2 2 2 0 FlxA-like protein DUF823 PF05689.6 KEZ44214.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) Ribosomal_L37 PF08561.5 KEZ44215.1 - 1.1e-30 104.9 3.6 1e-23 82.6 0.4 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 KEZ44216.1 - 0.00021 21.4 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 KEZ44216.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase RRM_1 PF00076.17 KEZ44217.1 - 9.6e-35 118.0 5.3 9.4e-18 63.6 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44217.1 - 1.3e-29 102.0 0.1 1.6e-13 50.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44217.1 - 2.8e-14 52.7 0.0 1.6e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_2 PF13347.1 KEZ44218.1 - 2.9e-10 39.1 12.2 2.9e-10 39.1 8.5 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KEZ44218.1 - 0.19 11.5 3.8 0.4 10.5 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family RhoGEF PF00621.15 KEZ44219.1 - 1.9e-32 112.5 0.0 4.6e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 KEZ44219.1 - 1.6e-12 47.4 0.7 4e-12 46.1 0.5 1.6 1 0 0 1 1 1 1 BAR domain Seryl_tRNA_N PF02403.17 KEZ44219.1 - 1.6 8.7 6.5 1.1 9.2 1.0 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Telomerase_RBD PF12009.3 KEZ44220.1 - 1.1e-43 148.4 0.4 2.3e-43 147.3 0.3 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KEZ44220.1 - 4.5e-13 49.0 0.0 1.7e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.1 KEZ44221.1 - 4e-18 65.2 2.4 1.5e-17 63.4 1.7 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CYSTM PF12734.2 KEZ44222.1 - 4.2e-06 26.7 31.8 4.2e-06 26.7 22.1 4.2 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance SH3_9 PF14604.1 KEZ44223.1 - 2.2e-31 107.1 3.4 4.6e-16 58.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KEZ44223.1 - 4.8e-25 86.6 4.7 2.8e-13 49.0 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KEZ44223.1 - 1.4e-19 69.3 0.0 1.9e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KEZ44223.1 - 1.6e-11 44.2 0.0 2.9e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Chlam_OMP6 PF03504.8 KEZ44223.1 - 0.31 11.3 1.3 2.5 8.4 0.2 2.7 3 0 0 3 3 3 0 Chlamydia cysteine-rich outer membrane protein 6 Fungal_trans PF04082.13 KEZ44224.1 - 7.9e-18 64.2 0.3 1.2e-17 63.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEZ44226.1 - 0.00098 19.3 2.6 0.35 11.3 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ44226.1 - 0.0024 18.0 3.9 0.44 11.0 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ44226.1 - 0.027 14.7 0.4 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 KEZ44226.1 - 0.038 13.2 0.3 0.082 12.1 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 KEZ44226.1 - 0.097 12.6 2.5 7.7 6.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RING_2 PF13639.1 KEZ44227.1 - 1.5e-12 47.0 3.1 2.8e-12 46.2 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEZ44227.1 - 6.2e-11 42.2 0.4 6.2e-11 42.2 0.3 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEZ44227.1 - 3.5e-06 26.7 0.3 6.8e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KEZ44227.1 - 2.1e-05 24.1 2.5 3.5e-05 23.4 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEZ44227.1 - 5.1e-05 23.2 3.8 9.7e-05 22.3 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ44227.1 - 0.00028 20.4 1.1 0.00048 19.7 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ44227.1 - 0.00047 19.7 3.0 0.00078 19.0 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KEZ44227.1 - 0.0006 19.4 1.4 0.0019 17.9 1.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 KEZ44227.1 - 0.36 10.8 4.8 5.1 7.1 3.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain p450 PF00067.17 KEZ44228.1 - 1.4e-76 257.9 0.0 1.9e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3332 PF11810.3 KEZ44229.1 - 1.9 8.1 0.1 9.1 5.8 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Reo_sigmaC PF04582.7 KEZ44229.1 - 7.1 5.7 2.3 13 4.8 1.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fungal_trans PF04082.13 KEZ44230.1 - 8.8e-15 54.2 0.1 4.6e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ44230.1 - 6.1e-09 35.6 10.7 1e-08 34.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain URO-D PF01208.12 KEZ44231.1 - 2.3e-119 398.3 0.0 2.6e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.3 KEZ44232.1 - 5.2e-16 58.7 9.9 1.6e-12 47.5 2.7 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) MARVEL PF01284.18 KEZ44233.1 - 0.16 11.7 7.1 0.27 11.0 4.8 1.7 1 1 0 1 1 1 0 Membrane-associating domain Pox_A14 PF05767.7 KEZ44233.1 - 0.29 11.1 2.5 0.65 9.9 0.7 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Velvet PF11754.3 KEZ44234.1 - 1.2e-71 240.5 0.0 1.8e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Velvet factor LRR_4 PF12799.2 KEZ44235.1 - 6.7e-15 54.3 8.0 7.1e-06 25.5 1.9 4.9 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ44235.1 - 1.4e-10 40.7 3.8 1.6e-05 24.5 1.4 3.5 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 KEZ44235.1 - 1.2e-06 27.6 7.9 8.2 6.8 0.0 6.3 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KEZ44235.1 - 1.9e-06 27.3 3.6 18 5.8 0.0 6.1 5 1 1 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 KEZ44235.1 - 0.0025 17.7 5.2 10 6.8 0.1 6.0 8 0 0 8 8 8 1 Leucine rich repeat CAP_GLY PF01302.20 KEZ44235.1 - 0.0027 17.3 0.3 0.0065 16.1 0.2 1.6 1 1 0 1 1 1 1 CAP-Gly domain Aldo_ket_red PF00248.16 KEZ44236.1 - 6e-58 195.8 0.0 6.8e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldolase_II PF00596.16 KEZ44237.1 - 6.1e-42 143.3 0.0 7.3e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Sec20 PF03908.8 KEZ44238.1 - 1.9e-11 43.4 1.5 3.8e-11 42.5 0.4 2.0 2 0 0 2 2 2 1 Sec20 PEP-utilisers_N PF05524.8 KEZ44238.1 - 0.0023 17.7 9.1 0.27 11.0 1.4 3.3 2 1 1 3 3 3 2 PEP-utilising enzyme, N-terminal DUF342 PF03961.8 KEZ44238.1 - 0.26 9.6 1.5 0.49 8.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 KEZ44238.1 - 1.7 7.7 9.3 6.8 5.7 6.4 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.9 KEZ44238.1 - 7.8 6.4 8.7 2.6 7.9 3.6 2.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) MRP_L53 PF10780.4 KEZ44239.1 - 4.6e-20 71.3 2.1 4.6e-20 71.3 0.8 1.5 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 Paramyx_P_V_C PF03210.8 KEZ44239.1 - 0.051 13.4 0.2 0.051 13.4 0.1 1.1 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF3006 PF11213.3 KEZ44239.1 - 0.057 13.1 0.0 0.093 12.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3006) DUF971 PF06155.7 KEZ44239.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Pyrophosphatase PF00719.14 KEZ44240.1 - 7.2e-53 178.2 0.2 9e-53 177.8 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase ApoO PF09769.4 KEZ44241.1 - 3.2e-48 163.4 0.1 3.2e-48 163.4 0.1 1.9 3 0 0 3 3 3 1 Apolipoprotein O Dus PF01207.12 KEZ44242.1 - 2e-43 148.3 1.4 1.6e-42 145.3 0.8 2.3 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 KEZ44242.1 - 0.06 12.4 0.5 0.25 10.4 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Glutaredoxin PF00462.19 KEZ44244.1 - 4.5e-12 45.7 0.1 1.6e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 KEZ44244.1 - 0.00031 20.8 0.0 0.00083 19.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain PcrB PF01884.12 KEZ44244.1 - 0.026 13.7 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 PcrB family Thioredoxin_9 PF14595.1 KEZ44244.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF1765 PF08578.5 KEZ44245.1 - 1.8e-42 144.3 2.9 3.5e-42 143.4 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Fungal_trans_2 PF11951.3 KEZ44247.1 - 4.2e-06 25.6 0.8 6.8e-06 24.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ44247.1 - 0.0041 16.9 2.3 0.0073 16.1 1.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.13 KEZ44248.1 - 9.8e-36 123.2 0.1 1.4e-35 122.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain Tubulin PF00091.20 KEZ44249.1 - 8.5e-64 215.3 0.0 1.1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEZ44249.1 - 3.8e-44 149.7 0.0 6.4e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KEZ44249.1 - 0.00066 19.1 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 KEZ44250.1 - 4.6e-14 51.7 0.3 1.4e-08 34.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44250.1 - 1.4e-12 47.2 0.4 3.7e-06 26.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44250.1 - 7.3e-10 38.6 0.3 1e-05 25.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 KEZ44251.1 - 5.6e-20 71.7 1.1 5.6e-20 71.7 0.8 2.9 2 1 0 2 2 2 1 Sds3-like Uteroglobin PF01099.12 KEZ44251.1 - 0.19 11.5 1.0 0.48 10.2 0.7 1.7 1 1 0 1 1 1 0 Uteroglobin family Coiled-coil_56 PF09813.4 KEZ44252.1 - 0.00016 21.5 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 PepSY_TM PF03929.11 KEZ44252.1 - 1.7 9.1 4.0 2.6 8.6 2.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DUF3453 PF11935.3 KEZ44253.1 - 9.2e-70 234.7 0.3 1.6e-69 234.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) 3Beta_HSD PF01073.14 KEZ44255.1 - 3.5e-19 68.5 0.0 7.6e-18 64.1 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ44255.1 - 1.4e-11 44.3 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KEZ44255.1 - 5e-06 26.5 0.1 2.1e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KEZ44255.1 - 7.2e-06 25.1 0.0 0.00031 19.7 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 KEZ44255.1 - 0.00049 20.1 0.4 0.0048 16.9 0.3 2.3 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEZ44255.1 - 0.0019 17.9 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEZ44255.1 - 0.0059 15.5 0.0 0.012 14.5 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Paramecium_SA PF01508.11 KEZ44256.1 - 5.6 7.2 12.1 2.5 8.3 0.5 2.3 2 0 0 2 2 2 0 Paramecium surface antigen domain PGM_PMM_I PF02878.11 KEZ44257.1 - 3.2e-33 114.1 0.0 4.6e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KEZ44257.1 - 4.4e-24 84.6 0.0 8.8e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KEZ44257.1 - 2.6e-15 56.6 0.1 5.5e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KEZ44257.1 - 1.6e-08 34.3 0.0 4.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DSPn PF14671.1 KEZ44258.1 - 3.2e-43 147.0 0.0 1.4e-39 135.3 0.0 3.0 3 0 0 3 3 3 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KEZ44258.1 - 3.9e-17 62.0 0.0 9.9e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEZ44258.1 - 1.2e-07 31.3 0.0 2.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KEZ44258.1 - 0.00063 19.8 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KEZ44258.1 - 0.014 15.6 0.8 0.038 14.2 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 KEZ44258.1 - 0.021 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF3439 PF11921.3 KEZ44258.1 - 0.048 13.4 1.1 0.15 11.8 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CDKN3 PF05706.7 KEZ44258.1 - 0.052 12.9 0.1 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) MFS_1 PF07690.11 KEZ44259.1 - 1.4e-37 129.2 46.1 3.3e-36 124.7 32.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Pcc1 PF09341.5 KEZ44259.1 - 1.2e-24 86.1 0.4 2.2e-24 85.3 0.3 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 TRI12 PF06609.8 KEZ44259.1 - 1e-10 40.4 13.2 1.8e-10 39.7 9.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HLH PF00010.21 KEZ44260.1 - 5.6e-17 61.1 0.0 1.8e-16 59.5 0.0 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tropomyosin PF00261.15 KEZ44260.1 - 0.028 13.5 0.9 0.062 12.3 0.6 1.5 1 0 0 1 1 1 0 Tropomyosin ATG11 PF10377.4 KEZ44261.1 - 8.2e-38 129.2 1.2 3e-37 127.4 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.7 KEZ44261.1 - 0.0012 17.7 6.1 0.0012 17.7 4.2 5.8 2 2 2 5 5 5 1 Autophagy protein Apg17 IncA PF04156.9 KEZ44261.1 - 0.0026 17.3 17.2 0.0026 17.3 11.9 7.5 3 1 1 5 5 5 1 IncA protein DUF2779 PF11074.3 KEZ44261.1 - 2.6 8.0 7.8 4.1 7.4 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function(DUF2779) Reo_sigmaC PF04582.7 KEZ44261.1 - 5.1 6.1 30.9 0.018 14.2 3.0 5.8 2 2 1 5 5 5 0 Reovirus sigma C capsid protein CENP-H PF05837.7 KEZ44262.1 - 7.4e-20 71.1 2.8 9e-20 70.8 1.9 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) FAD-oxidase_C PF02913.14 KEZ44262.1 - 0.0083 15.4 0.2 0.0098 15.2 0.2 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF3708 PF12501.3 KEZ44262.1 - 0.0087 15.9 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Phosphate ATP-binding cassette transporter Fez1 PF06818.10 KEZ44262.1 - 0.009 16.0 1.0 0.011 15.7 0.7 1.1 1 0 0 1 1 1 1 Fez1 DUF818 PF05677.7 KEZ44262.1 - 0.059 12.0 0.2 0.072 11.8 0.1 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) IncA PF04156.9 KEZ44262.1 - 0.78 9.2 6.4 0.41 10.2 3.1 1.4 1 1 0 1 1 1 0 IncA protein HMG_box PF00505.14 KEZ44263.1 - 8.6e-25 86.7 1.5 1.1e-24 86.4 1.0 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEZ44263.1 - 2.6e-19 69.3 1.8 3.5e-19 68.9 1.2 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KEZ44263.1 - 0.00072 19.2 0.8 0.0014 18.4 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 KEZ44263.1 - 0.023 14.9 0.2 0.059 13.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) Prp31_C PF09785.4 KEZ44263.1 - 0.048 14.0 1.9 0.057 13.8 1.3 1.2 1 0 0 1 1 1 0 Prp31 C terminal domain DUF4051 PF13260.1 KEZ44264.1 - 0.31 10.3 1.2 0.54 9.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) 5TM-5TMR_LYT PF07694.7 KEZ44264.1 - 0.66 9.2 5.3 1.4 8.2 0.4 1.9 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Sod_Cu PF00080.15 KEZ44265.1 - 6.1e-18 65.3 0.1 1.2e-17 64.4 0.1 1.5 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CVNH PF08881.5 KEZ44266.1 - 2.3e-14 53.4 0.2 3.9e-06 27.0 0.0 2.3 2 0 0 2 2 2 2 CVNH domain DUF202 PF02656.10 KEZ44268.1 - 0.0085 16.2 4.5 0.0085 16.2 3.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Glyco_hydro_47 PF01532.15 KEZ44269.1 - 6.7e-166 552.4 0.0 8.3e-166 552.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 KEZ44269.1 - 0.0017 17.7 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Matrilin_ccoil PF10393.4 KEZ44270.1 - 0.15 11.4 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Ribosomal_S19 PF00203.16 KEZ44271.1 - 7.1e-35 118.4 0.3 1.1e-34 117.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 AA_permease PF00324.16 KEZ44274.1 - 1.5e-136 455.5 34.1 1.9e-136 455.1 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ44274.1 - 6.8e-37 127.0 33.7 9.2e-37 126.5 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease SnoaL_2 PF12680.2 KEZ44275.1 - 0.0038 17.6 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like domain BNR PF02012.15 KEZ44276.1 - 1.4e-09 36.2 43.9 0.095 12.5 0.1 11.4 11 0 0 11 11 11 5 BNR/Asp-box repeat DUF2561 PF10812.3 KEZ44276.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Cytochrom_B_N PF00033.14 KEZ44276.1 - 0.0027 17.0 0.5 0.0049 16.2 0.3 1.3 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 KEZ44276.1 - 0.022 14.1 0.1 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 LAM_C PF12544.3 KEZ44278.1 - 0.00011 22.2 0.0 0.00027 20.9 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 KEZ44278.1 - 0.013 15.7 0.4 0.064 13.4 0.3 2.1 1 1 0 1 1 1 0 Radical SAM superfamily Rhomboid PF01694.17 KEZ44279.1 - 3.4e-25 88.7 11.5 3.4e-25 88.7 8.0 1.6 1 1 0 1 1 1 1 Rhomboid family Leu_zip PF15294.1 KEZ44279.1 - 1.3 8.1 4.7 0.17 10.9 0.6 1.4 2 0 0 2 2 2 0 Leucine zipper IU_nuc_hydro PF01156.14 KEZ44280.1 - 2.1e-54 184.8 0.0 1.2e-42 146.2 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase P34-Arc PF04045.9 KEZ44282.1 - 5.5e-87 291.0 1.8 3.4e-83 278.6 0.4 2.0 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc Rax2 PF12768.2 KEZ44283.1 - 2.4e-90 302.5 8.0 4.2e-79 265.6 0.1 4.3 3 1 1 4 4 4 4 Cortical protein marker for cell polarity Kelch_6 PF13964.1 KEZ44283.1 - 0.00031 20.7 11.2 3.6 7.9 0.0 7.4 7 0 0 7 7 7 2 Kelch motif PQQ_3 PF13570.1 KEZ44283.1 - 0.5 10.7 22.7 3.6 8.0 0.6 6.8 7 0 0 7 7 7 0 PQQ-like domain zf-H2C2_2 PF13465.1 KEZ44284.1 - 4.5e-12 45.6 13.3 2.6e-06 27.4 0.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ44284.1 - 1.4e-11 43.9 11.0 1.9e-05 24.7 3.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ44284.1 - 1e-08 34.9 8.4 0.00019 21.5 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KEZ44284.1 - 1.9e-05 24.6 1.5 1.9e-05 24.6 1.0 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEZ44284.1 - 6.8e-05 22.8 6.3 0.00011 22.1 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KEZ44284.1 - 0.0015 18.4 7.3 0.0038 17.0 1.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEZ44284.1 - 0.02 15.0 1.2 0.02 15.0 0.8 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KEZ44284.1 - 7.9 6.3 10.9 0.56 9.9 0.6 2.8 3 0 0 3 3 3 0 BED zinc finger SF3b1 PF08920.5 KEZ44285.1 - 1.7e-27 96.2 3.5 2.2e-26 92.6 2.4 2.6 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KEZ44285.1 - 6.9e-15 55.1 2.5 0.013 15.8 0.0 8.3 7 3 3 10 10 10 5 HEAT repeats HEAT PF02985.17 KEZ44285.1 - 2.5e-09 36.4 9.3 1.2 9.3 0.0 9.3 10 0 0 10 10 10 2 HEAT repeat HhH-GPD PF00730.20 KEZ44285.1 - 5.2e-09 36.3 0.0 1.8e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HEAT_EZ PF13513.1 KEZ44285.1 - 2.2e-08 34.3 5.3 0.98 9.9 0.0 7.4 5 2 2 7 7 7 2 HEAT-like repeat Adaptin_N PF01602.15 KEZ44285.1 - 8.5e-06 24.3 0.2 0.0016 16.8 0.0 3.1 2 2 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KEZ44285.1 - 6.7e-05 23.2 0.2 0.61 10.5 0.0 5.1 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region HHH PF00633.18 KEZ44285.1 - 0.003 17.1 0.0 0.0099 15.5 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif NUC173 PF08161.7 KEZ44285.1 - 0.019 14.3 0.4 6.1 6.1 0.0 3.5 4 0 0 4 4 4 0 NUC173 domain CLASP_N PF12348.3 KEZ44285.1 - 0.023 14.0 0.0 1.9 7.7 0.0 3.5 4 0 0 4 4 4 0 CLASP N terminal RRM_1 PF00076.17 KEZ44286.1 - 7.4e-26 89.5 0.1 6.9e-11 41.6 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44286.1 - 3.1e-16 59.1 0.0 0.00012 21.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44286.1 - 3.5e-14 52.3 0.0 8.8e-05 22.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S13_N PF08069.7 KEZ44287.1 - 4.8e-28 96.7 0.4 9.4e-28 95.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KEZ44287.1 - 2.8e-20 71.8 0.1 4.3e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KEZ44287.1 - 0.067 12.9 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain Dpy-30 PF05186.8 KEZ44288.1 - 1.4e-06 27.7 0.2 4.6e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 Dpy-30 motif Tn7_Tnp_TnsA_C PF08721.6 KEZ44288.1 - 0.099 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal APH PF01636.18 KEZ44289.1 - 1.1e-41 143.1 0.0 8.2e-41 140.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEZ44289.1 - 4.9e-06 25.8 0.0 9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KEZ44289.1 - 5.7e-05 22.7 0.0 8.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KEZ44289.1 - 0.011 14.3 0.0 0.035 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 KEZ44289.1 - 0.058 12.3 0.0 0.57 9.1 0.0 2.3 1 1 0 1 1 1 0 Fructosamine kinase Arrestin_N PF00339.24 KEZ44290.1 - 2.5e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KEZ44290.1 - 0.033 14.2 0.0 1.2 9.2 0.0 2.4 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.5 KEZ44290.1 - 0.11 11.5 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Rgp1 Cas_Csx9 PF09658.5 KEZ44291.1 - 0.056 12.2 0.1 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) LSM PF01423.17 KEZ44292.1 - 6e-17 60.9 0.0 8.1e-17 60.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEZ44292.1 - 0.00095 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.6 KEZ44292.1 - 2.4 6.5 8.6 2.8 6.3 5.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RNA_pol_Rpb2_6 PF00562.23 KEZ44293.1 - 4.3e-115 384.5 0.0 6.2e-115 384.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Tyrosinase PF00264.15 KEZ44293.1 - 5.3e-53 180.4 7.6 9.7e-53 179.5 5.2 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_1 PF04563.10 KEZ44293.1 - 1.1e-28 99.5 0.0 1.9e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KEZ44293.1 - 5e-25 87.0 0.0 1.5e-24 85.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KEZ44293.1 - 3.8e-20 71.5 0.0 1e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 KEZ44293.1 - 2e-18 66.4 0.0 4.5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KEZ44293.1 - 2.8e-13 49.9 0.0 9.7e-13 48.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 DUF3989 PF13150.1 KEZ44293.1 - 0.045 13.2 0.1 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) She9_MDM33 PF05546.6 KEZ44293.1 - 0.16 11.5 0.2 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family Arf PF00025.16 KEZ44294.1 - 2e-41 141.1 0.0 2.3e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEZ44294.1 - 1.1e-18 67.1 0.0 1.2e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ44294.1 - 8.4e-11 42.4 0.0 1.5e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KEZ44294.1 - 3.8e-06 26.2 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KEZ44294.1 - 6.9e-06 25.6 0.0 2.7e-05 23.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEZ44294.1 - 7.6e-06 25.2 0.0 9.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KEZ44294.1 - 8.2e-06 24.7 0.1 1.1e-05 24.3 0.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 KEZ44294.1 - 3.7e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KEZ44294.1 - 0.014 15.1 0.1 0.26 11.0 0.1 2.1 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 KEZ44294.1 - 0.15 11.3 0.2 0.63 9.3 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Beta_elim_lyase PF01212.16 KEZ44295.1 - 3.3e-66 223.3 0.0 4e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KEZ44295.1 - 1.5e-06 27.4 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEZ44295.1 - 0.00025 19.4 0.0 0.00038 18.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEZ44295.1 - 0.0064 15.5 0.0 0.02 13.9 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KEZ44295.1 - 0.0074 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Trehalase PF01204.13 KEZ44296.1 - 5.6e-121 404.7 0.2 7e-120 401.0 0.1 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 KEZ44296.1 - 0.007 15.1 0.1 0.016 13.9 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Proteasome PF00227.21 KEZ44297.1 - 4.6e-46 156.5 0.1 5.5e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KEZ44297.1 - 1.1e-11 43.8 0.2 2.6e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Sel1 PF08238.7 KEZ44298.1 - 1.5e-13 50.8 8.1 0.001 19.6 0.3 4.3 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.7 KEZ44299.1 - 3.3e-72 242.7 0.0 9.5e-71 237.9 0.0 2.3 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KEZ44299.1 - 2.1e-34 117.3 0.1 8.2e-34 115.4 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.1 KEZ44300.1 - 9.1e-30 102.5 1.6 2e-29 101.5 1.1 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KEZ44300.1 - 2.4e-21 75.1 0.0 3.7e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44300.1 - 1.2e-17 63.6 0.0 2.4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44300.1 - 8.8e-09 35.0 0.0 1.2e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KEZ44300.1 - 2.3e-06 26.7 7.2 3.4e-06 26.2 0.4 2.9 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal DAO PF01266.19 KEZ44300.1 - 0.2 10.4 0.9 0.29 10.0 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RRM_1 PF00076.17 KEZ44301.1 - 2.1e-16 59.2 0.2 1.4e-06 27.8 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44301.1 - 3.3e-16 59.0 0.0 5.8e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44301.1 - 1.3e-05 24.9 0.0 0.00025 20.8 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasom_Rpn13 PF04683.8 KEZ44302.1 - 1.3e-26 92.4 0.0 2.2e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 KEZ44302.1 - 0.0059 16.1 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 L27_2 EF1_GNE PF00736.14 KEZ44303.1 - 2e-32 110.7 1.3 3.6e-32 109.9 0.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KEZ44303.1 - 9.3e-15 54.4 6.9 9.3e-15 54.4 4.8 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KEZ44303.1 - 7.8e-05 23.0 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEZ44303.1 - 0.00062 19.7 0.6 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KEZ44303.1 - 0.083 12.7 0.5 0.72 9.7 0.3 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 KEZ44303.1 - 0.47 10.0 7.5 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Sld5 PF05916.6 KEZ44304.1 - 2.2e-12 47.1 0.0 2.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sulfate_transp PF00916.15 KEZ44305.1 - 1.3e-35 122.8 0.7 2.2e-35 122.0 0.1 1.7 1 1 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 KEZ44305.1 - 1.4e-12 47.2 0.0 2.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KEZ44305.1 - 4.8e-10 38.8 0.0 9.2e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain Kinesin PF00225.18 KEZ44306.1 - 3e-96 322.0 0.0 3e-96 322.0 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Spore_coat_CotO PF14153.1 KEZ44306.1 - 1.7 8.0 8.8 3.4 7.0 6.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Baculo_gp64 PF03273.8 KEZ44306.1 - 1.7 6.7 4.0 2.6 6.1 2.8 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Vezatin PF12632.2 KEZ44307.1 - 1.4e-53 181.5 0.0 2.1e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Vma12 PF11712.3 KEZ44307.1 - 0.031 13.9 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase O-antigen_lig PF13425.1 KEZ44307.1 - 0.19 11.7 1.3 0.36 10.8 0.9 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4231 PF14015.1 KEZ44307.1 - 0.82 9.6 4.0 2.4 8.1 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Rab5ip PF07019.7 KEZ44308.1 - 4.1e-20 71.6 7.6 5.2e-20 71.3 5.3 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SNARE PF05739.14 KEZ44309.1 - 5.1e-09 35.7 3.0 2.6e-08 33.4 0.2 2.6 2 0 0 2 2 2 1 SNARE domain TPR_12 PF13424.1 KEZ44310.1 - 3e-17 62.3 3.7 1.9e-07 30.9 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Patatin PF01734.17 KEZ44310.1 - 3.7e-13 49.8 0.0 1.7e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 KEZ44310.1 - 2e-06 27.5 6.2 0.0011 18.7 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ44310.1 - 4.8e-06 25.9 0.2 0.021 14.5 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ44310.1 - 7.5e-06 26.4 0.4 0.3 11.8 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ44310.1 - 9.6e-06 25.1 0.1 0.015 14.8 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_6 PF13174.1 KEZ44310.1 - 1.1e-05 25.5 1.3 0.25 11.9 0.1 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ44310.1 - 1.3e-05 25.4 1.6 0.13 12.6 0.1 3.7 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ44310.1 - 6e-05 22.4 0.2 0.0016 17.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ44310.1 - 7e-05 22.4 6.1 0.002 17.8 0.3 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ44310.1 - 0.00018 21.8 4.2 1.6 9.6 0.1 4.3 3 1 1 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KEZ44310.1 - 0.00019 21.4 0.0 1 9.5 0.0 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KEZ44310.1 - 0.0003 20.9 4.5 0.43 11.1 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ44310.1 - 0.00044 19.8 0.0 0.31 10.9 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ44310.1 - 0.051 13.6 0.7 7.3 6.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4071 PF13281.1 KEZ44310.1 - 0.052 12.3 0.1 11 4.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4071) TPR_17 PF13431.1 KEZ44310.1 - 0.061 13.5 0.1 2.9 8.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat COG4 PF08318.7 KEZ44311.1 - 9.3e-96 320.4 0.0 1.3e-95 319.9 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Clr5 PF14420.1 KEZ44312.1 - 1.6e-07 31.1 0.1 3.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Clr5 domain DUF4110 PF13422.1 KEZ44312.1 - 0.051 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) MMR_HSR1 PF01926.18 KEZ44313.1 - 4.8e-06 26.5 0.0 1.8e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ44313.1 - 0.00029 20.0 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KEZ44313.1 - 0.0036 16.4 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KEZ44313.1 - 0.0065 16.9 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 KEZ44313.1 - 0.0066 17.2 0.0 0.017 15.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain T2SE PF00437.15 KEZ44313.1 - 0.0087 14.9 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 KEZ44313.1 - 0.012 15.1 0.1 0.029 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEZ44313.1 - 0.014 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KEZ44313.1 - 0.024 14.7 0.2 0.077 13.1 0.1 1.8 2 1 0 2 2 1 0 AAA domain PIF1 PF05970.9 KEZ44313.1 - 0.043 12.7 0.1 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.7 KEZ44313.1 - 0.059 13.0 0.5 0.33 10.5 0.3 2.0 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 KEZ44313.1 - 0.067 12.0 0.3 0.099 11.4 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain FeoB_N PF02421.13 KEZ44313.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 KEZ44313.1 - 0.084 12.4 0.2 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ44313.1 - 0.1 12.5 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 KEZ44313.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein PduV-EutP PF10662.4 KEZ44313.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 KEZ44313.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family E1-E2_ATPase PF00122.15 KEZ44314.1 - 7.6e-57 191.9 0.0 1.4e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ44314.1 - 2.6e-43 147.6 0.8 4.6e-43 146.8 0.6 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ44314.1 - 1.3e-25 91.0 0.0 4.7e-25 89.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ44314.1 - 5.4e-20 70.6 0.0 1.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KEZ44314.1 - 2.7e-13 49.6 0.0 5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ44314.1 - 5.2e-12 46.3 0.0 1.1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ44314.1 - 2.7e-05 23.8 0.8 2.7e-05 23.8 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 KEZ44315.1 - 3.4e-38 130.0 0.0 6.1e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KEZ44315.1 - 5.6e-08 31.8 0.9 9.6e-08 31.1 0.0 1.8 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KEZ44315.1 - 0.0096 15.5 0.3 0.084 12.4 0.0 2.3 3 0 0 3 3 3 1 ScpA/B protein TBCA PF02970.11 KEZ44316.1 - 1.2e-16 60.5 5.9 1.5e-16 60.1 4.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Geminin PF07412.7 KEZ44316.1 - 0.0059 16.3 1.9 0.0071 16.0 1.3 1.3 1 0 0 1 1 1 1 Geminin IncA PF04156.9 KEZ44316.1 - 0.033 13.7 4.7 0.04 13.5 3.3 1.1 1 0 0 1 1 1 0 IncA protein TAN PF11640.3 KEZ44316.1 - 0.052 13.2 0.1 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair APG6 PF04111.7 KEZ44316.1 - 0.07 12.1 2.4 0.082 11.9 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Phage_lysis PF03245.8 KEZ44316.1 - 0.083 12.8 2.9 0.1 12.5 1.3 1.8 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein DALR_2 PF09190.6 KEZ44316.1 - 0.26 11.5 1.0 15 5.8 0.7 2.7 1 1 0 1 1 1 0 DALR domain Pox_A_type_inc PF04508.7 KEZ44316.1 - 0.33 10.8 2.0 1.2 9.0 0.1 2.8 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Sel1 PF08238.7 KEZ44318.1 - 2.3e-18 66.2 0.1 3e-06 27.6 0.0 3.7 3 0 0 3 3 3 3 Sel1 repeat TPR_12 PF13424.1 KEZ44318.1 - 0.25 11.2 1.4 8.8 6.3 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Mob1_phocein PF03637.12 KEZ44319.1 - 4.5e-39 133.9 2.4 3.3e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 KEZ44320.1 - 8.9e-28 97.1 0.0 8.9e-28 97.1 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein Peptidase_M55 PF04951.8 KEZ44320.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 D-aminopeptidase BUD22 PF09073.5 KEZ44320.1 - 3.6 6.5 30.7 0.084 11.9 14.9 2.1 2 0 0 2 2 2 0 BUD22 DUF3336 PF11815.3 KEZ44321.1 - 1.1e-38 132.0 0.1 2.6e-38 130.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KEZ44321.1 - 4.6e-14 52.8 0.1 1.1e-13 51.5 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Lipase_GDSL PF00657.17 KEZ44322.1 - 4.2e-18 66.0 0.2 4.7e-17 62.6 0.2 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ44322.1 - 8.8e-18 65.0 0.4 1.3e-17 64.5 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BOP1NT PF08145.7 KEZ44323.1 - 1.4e-99 333.0 10.7 1.9e-99 332.6 7.4 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KEZ44323.1 - 1.8e-17 62.4 7.5 2.1e-11 43.2 0.9 4.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Arylsulfotrans PF05935.6 KEZ44323.1 - 0.082 11.4 0.2 0.33 9.3 0.1 1.8 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) Mito_carr PF00153.22 KEZ44324.1 - 2.8e-68 225.6 0.5 5.7e-22 77.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IU_nuc_hydro PF01156.14 KEZ44325.1 - 4e-75 252.9 0.0 6.7e-75 252.2 0.0 1.3 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 KEZ44325.1 - 6.9e-07 28.7 9.1 6.9e-07 28.7 6.3 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF2924 PF11149.3 KEZ44325.1 - 0.1 12.5 3.7 1.4 8.9 2.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) Myc_N PF01056.13 KEZ44325.1 - 0.56 9.3 21.7 1 8.4 3.7 3.3 3 0 0 3 3 3 0 Myc amino-terminal region IMS PF00817.15 KEZ44326.1 - 2e-41 141.2 0.0 4.4e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEZ44326.1 - 4.7e-19 68.5 0.0 9.5e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KEZ44326.1 - 4.9e-12 45.7 8.5 3.3e-06 26.9 0.2 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) HHH_5 PF14520.1 KEZ44326.1 - 2.2e-05 24.5 0.1 7.2e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.3 KEZ44326.1 - 9.1e-05 22.2 0.5 0.00048 20.0 0.1 2.5 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.21 KEZ44326.1 - 0.0076 16.3 0.0 0.026 14.6 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KEZ44326.1 - 0.0097 15.7 0.1 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain DUF1805 PF08827.6 KEZ44326.1 - 0.087 12.6 0.0 0.3 10.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) NDUF_B4 PF07225.7 KEZ44326.1 - 5.8 6.7 6.8 1.8 8.4 0.6 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) RRM_1 PF00076.17 KEZ44328.1 - 7.4e-17 60.7 0.0 1.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44328.1 - 9.2e-10 38.3 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ44328.1 - 5.5e-08 32.5 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KEZ44328.1 - 5.6e-06 26.7 5.6 5.6e-06 26.7 3.9 3.5 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Anp1 PF03452.9 KEZ44329.1 - 2.6e-103 344.8 0.0 3.4e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Anp1 DUF2763 PF10961.3 KEZ44329.1 - 0.039 14.3 0.1 0.073 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) UQ_con PF00179.21 KEZ44330.1 - 4.5e-33 113.6 0.0 5.2e-33 113.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KEZ44330.1 - 0.15 11.9 0.3 0.2 11.5 0.2 1.4 1 1 0 1 1 1 0 RWD domain Cgr1 PF03879.9 KEZ44331.1 - 1.3e-39 134.7 28.1 1.5e-39 134.4 19.5 1.0 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 KEZ44331.1 - 0.55 10.5 11.1 0.64 10.3 7.7 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SprA-related PF12118.3 KEZ44331.1 - 0.91 8.7 11.2 1.1 8.5 7.8 1.1 1 0 0 1 1 1 0 SprA-related family Vfa1 PF08432.5 KEZ44331.1 - 2.7 7.9 13.1 3.2 7.7 9.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 KEZ44331.1 - 3.5 7.4 11.2 4.1 7.2 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med9 PF07544.8 KEZ44332.1 - 0.0043 16.7 4.1 0.017 14.8 0.5 3.0 3 0 0 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.1 KEZ44332.1 - 0.0062 15.0 1.4 0.0082 14.6 1.0 1.1 1 0 0 1 1 1 1 AAA domain DUF3357 PF11837.3 KEZ44332.1 - 0.013 15.3 0.2 0.13 12.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Fib_alpha PF08702.5 KEZ44332.1 - 0.015 15.3 7.0 0.051 13.6 4.7 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Mo25 PF08569.6 KEZ44332.1 - 0.049 12.6 1.1 0.068 12.1 0.7 1.2 1 0 0 1 1 1 0 Mo25-like Poty_PP PF08440.5 KEZ44332.1 - 0.13 11.3 1.2 0.19 10.7 0.8 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein DUF948 PF06103.6 KEZ44332.1 - 0.71 9.7 3.7 5.4 6.9 0.2 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 KEZ44332.1 - 0.89 9.3 5.1 1.4 8.6 0.6 2.2 1 1 0 2 2 2 0 Laminin Domain II Muted PF14942.1 KEZ44332.1 - 2.4 8.0 6.9 0.87 9.4 1.7 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TMF_TATA_bd PF12325.3 KEZ44332.1 - 2.6 7.8 9.5 0.7 9.6 3.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.1 KEZ44332.1 - 2.6 8.5 7.3 1 9.8 0.2 3.1 3 2 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 KEZ44332.1 - 2.9 7.9 6.0 9.5 6.2 1.6 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 KEZ44332.1 - 3.4 7.6 5.0 15 5.5 0.1 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 KEZ44332.1 - 4.3 7.8 9.0 59 4.1 2.5 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Atg14 PF10186.4 KEZ44332.1 - 6.9 5.5 9.3 1.5 7.6 2.7 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3818 PF12825.2 KEZ44333.1 - 3.8e-130 433.5 6.1 6e-130 432.8 4.2 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KEZ44333.1 - 6.4e-42 142.4 0.8 1.6e-41 141.1 0.6 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KEZ44333.1 - 1.1e-14 54.1 5.1 1.8e-14 53.4 0.2 3.5 3 1 0 3 3 3 1 PX domain FAD_binding_2 PF00890.19 KEZ44334.1 - 1.3e-123 412.9 0.8 1.7e-123 412.6 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KEZ44334.1 - 6.8e-47 158.5 0.2 1e-46 157.9 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 KEZ44334.1 - 4.4e-05 22.7 0.1 0.08 12.0 0.0 2.6 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 KEZ44334.1 - 0.00019 21.3 0.2 0.017 15.0 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ44334.1 - 0.00021 20.3 0.0 0.0022 16.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KEZ44334.1 - 0.00035 19.5 1.2 0.044 12.6 1.5 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KEZ44334.1 - 0.015 14.3 0.2 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KEZ44334.1 - 0.11 10.8 1.2 0.38 9.1 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein zf-GRF PF06839.7 KEZ44335.1 - 3.2e-06 26.9 7.4 6.3e-06 26.0 5.1 1.5 1 0 0 1 1 1 1 GRF zinc finger Flg_hook PF02120.11 KEZ44336.1 - 0.00016 21.2 0.5 0.028 14.0 0.0 2.7 2 0 0 2 2 2 2 Flagellar hook-length control protein FliK Oxysterol_BP PF01237.13 KEZ44337.1 - 2.4e-85 286.1 0.0 3.1e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.19 KEZ44338.1 - 1.7e-08 33.9 18.1 4.6e-07 29.3 1.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KEZ44338.1 - 3.9e-06 26.6 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ44338.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44338.1 - 0.019 14.9 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Tachystatin_B PF11478.3 KEZ44338.1 - 3.6 7.3 9.0 0.4 10.4 1.3 2.8 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B HET PF06985.6 KEZ44339.1 - 3.6e-28 98.4 0.1 8e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 KEZ44340.1 - 5.9e-20 71.8 0.0 1.2e-19 70.8 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HEAT PF02985.17 KEZ44341.1 - 0.023 14.7 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.1 KEZ44341.1 - 0.032 14.5 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats CAP_GLY PF01302.20 KEZ44342.1 - 3.8e-17 61.7 0.5 1.1e-16 60.2 0.1 2.0 2 0 0 2 2 2 1 CAP-Gly domain NPV_P10 PF05531.7 KEZ44342.1 - 0.13 12.5 8.7 1.7 8.9 0.7 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Glutaredoxin2_C PF04399.8 KEZ44342.1 - 0.17 11.4 4.3 1.7 8.2 0.4 3.1 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain TMF_TATA_bd PF12325.3 KEZ44342.1 - 0.22 11.2 29.3 0.099 12.3 5.3 4.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding FliD_N PF02465.13 KEZ44342.1 - 0.24 11.8 6.3 1.8 8.9 1.2 3.3 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus AAA_13 PF13166.1 KEZ44342.1 - 0.81 8.0 16.5 0.49 8.7 3.7 2.1 1 1 1 2 2 2 0 AAA domain Prominin PF05478.6 KEZ44342.1 - 1.1 6.7 2.6 1.7 6.0 1.8 1.4 1 0 0 1 1 1 0 Prominin zf-CCHC_4 PF14392.1 KEZ44342.1 - 4.1 7.1 4.9 5.4 6.7 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Phage_GP20 PF06810.6 KEZ44342.1 - 8.4 5.8 21.0 0.77 9.1 0.3 3.5 2 1 3 5 5 5 0 Phage minor structural protein GP20 Pkinase PF00069.20 KEZ44343.1 - 8e-36 123.5 0.0 5e-21 75.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44343.1 - 4.6e-14 52.1 0.0 7.7e-10 38.2 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEZ44343.1 - 0.00031 19.8 0.0 0.37 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEZ44343.1 - 0.00056 19.7 0.0 0.0065 16.2 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_38 PF01074.17 KEZ44344.1 - 2.5e-91 305.7 0.9 4.5e-91 304.9 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KEZ44344.1 - 1.1e-69 235.4 0.0 7.2e-69 232.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KEZ44344.1 - 3.1e-26 91.4 0.0 8e-26 90.0 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain SNARE_assoc PF09335.6 KEZ44345.1 - 1.1e-12 48.2 6.9 1.1e-12 48.2 4.8 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4349 PF14257.1 KEZ44345.1 - 0.29 10.3 0.0 0.29 10.3 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) IncA PF04156.9 KEZ44346.1 - 0.083 12.4 0.6 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 IncA protein Abhydrolase_6 PF12697.2 KEZ44347.1 - 2.5e-13 50.4 0.1 1.5e-12 47.9 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ44347.1 - 9.7e-10 38.3 0.0 8.4e-08 32.0 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ44347.1 - 1.4e-07 31.3 0.0 3.5e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold RtcR PF06956.6 KEZ44347.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Peptidase_S28 PF05577.7 KEZ44347.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DEAD PF00270.24 KEZ44348.1 - 1.2e-12 47.5 0.0 3.6e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ44348.1 - 2.9e-05 23.8 0.1 7.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 KEZ44348.1 - 0.00016 21.7 0.0 0.00076 19.6 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.10 KEZ44348.1 - 0.00033 20.5 0.0 0.02 14.7 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.24 KEZ44349.1 - 3.8e-15 55.2 35.6 7.1e-09 35.2 3.0 5.4 5 0 0 5 5 5 2 PHD-finger PHD_2 PF13831.1 KEZ44349.1 - 1.9e-09 36.6 2.3 1.9e-09 36.6 1.6 4.7 6 0 0 6 6 6 2 PHD-finger zf-HC5HC2H_2 PF13832.1 KEZ44349.1 - 2.3e-05 24.3 14.8 7.9e-05 22.6 0.2 4.4 3 1 1 4 4 4 2 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 KEZ44349.1 - 0.00018 21.1 20.5 0.01 15.5 4.3 3.9 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 BAH PF01426.13 KEZ44349.1 - 0.00064 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain Myb_DNA-binding PF00249.26 KEZ44349.1 - 0.0013 18.7 1.1 0.0021 18.0 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_1 PF00130.17 KEZ44349.1 - 0.0076 15.9 0.2 0.0076 15.9 0.2 5.1 4 1 1 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) TrkA_C PF02080.16 KEZ44349.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain DnaJ PF00226.26 KEZ44350.1 - 5.3e-26 90.1 2.5 1.1e-25 89.0 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEZ44350.1 - 5.7e-21 74.2 0.1 6.6e-18 64.3 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEZ44350.1 - 4.8e-14 52.1 17.9 8.5e-14 51.3 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEZ44350.1 - 0.0099 15.5 9.3 0.047 13.3 1.5 2.4 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KEZ44350.1 - 0.083 12.9 2.0 16 5.5 0.0 3.2 3 0 0 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 KEZ44350.1 - 0.17 11.6 6.2 2.6 7.9 1.2 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 KEZ44350.1 - 1.3 8.8 6.0 3.5 7.4 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) CPSF_A PF03178.10 KEZ44351.1 - 0.00035 19.7 0.0 0.0018 17.4 0.0 1.8 1 1 0 2 2 2 1 CPSF A subunit region WD40 PF00400.27 KEZ44351.1 - 0.0005 19.8 0.5 8.5 6.4 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat SEEK1 PF15357.1 KEZ44351.1 - 0.082 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 Ribosomal_L10 PF00466.15 KEZ44352.1 - 4.7e-25 87.4 0.0 9.3e-25 86.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KEZ44352.1 - 1.3e-17 63.9 8.5 1.8e-17 63.4 4.1 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.16 KEZ44353.1 - 6e-78 261.4 0.1 2.2e-77 259.6 0.0 1.9 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEZ44353.1 - 6.5e-40 137.0 4.4 1.2e-39 136.2 3.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KEZ44353.1 - 9.6e-19 67.4 0.0 2.1e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KEZ44353.1 - 2e-09 37.6 0.0 6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KEZ44353.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KEZ44353.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KEZ44353.1 - 0.09 13.0 0.3 1 9.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain Trypan_PARP PF05887.6 KEZ44353.1 - 0.38 10.5 3.8 0.38 10.5 0.7 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF1771 PF08590.5 KEZ44354.1 - 1.1e-13 51.0 10.9 2.4e-13 49.8 7.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KEZ44354.1 - 2.6e-10 40.3 0.0 7.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 KEZ44354.1 - 3.5e-08 32.9 4.0 0.00036 20.1 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 KEZ44354.1 - 0.0066 16.5 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 HBS1 N-terminus CUE PF02845.11 KEZ44354.1 - 0.17 11.3 0.0 0.51 9.8 0.0 1.8 2 0 0 2 2 2 0 CUE domain MFS_1 PF07690.11 KEZ44355.1 - 2.4e-13 49.5 22.2 2e-09 36.6 2.4 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF1212 PF06738.7 KEZ44355.1 - 0.12 11.8 0.5 0.23 10.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) TRI12 PF06609.8 KEZ44355.1 - 0.3 9.2 6.7 0.49 8.5 0.1 2.4 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) UDPGT PF00201.13 KEZ44356.1 - 2.1e-18 66.1 0.0 5.8e-18 64.7 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KEZ44356.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Cupin_8 PF13621.1 KEZ44357.1 - 7.6e-19 68.1 0.0 7.6e-18 64.9 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 KEZ44357.1 - 7.6e-10 39.0 0.0 2.1e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 KEZ44357.1 - 0.00025 20.6 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ44357.1 - 0.048 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box domain DEAD PF00270.24 KEZ44358.1 - 4.4e-44 149.9 2.8 5.4e-44 149.6 1.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ44358.1 - 1.1e-27 95.6 0.3 6.2e-27 93.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ44358.1 - 0.00018 21.3 0.1 0.0004 20.2 0.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KEZ44358.1 - 0.0011 18.5 0.2 0.003 17.1 0.1 1.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ44358.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KEZ44358.1 - 0.017 15.2 0.1 0.061 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 KEZ44358.1 - 0.038 13.0 0.0 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.9 KEZ44358.1 - 0.043 13.5 0.2 0.2 11.3 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 KEZ44358.1 - 0.057 12.5 0.2 0.3 10.1 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.16 KEZ44358.1 - 0.061 12.6 0.3 0.093 12.0 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 KEZ44358.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase Fanconi_A PF03511.9 KEZ44358.1 - 0.1 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein Clat_adaptor_s PF01217.15 KEZ44359.1 - 6.4e-18 64.8 0.2 1.8e-15 56.8 0.4 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain AAA_18 PF13238.1 KEZ44359.1 - 0.13 12.5 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 KEZ44360.1 - 7.8e-140 465.3 0.0 1.1e-139 464.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEZ44360.1 - 8.6e-25 87.5 0.0 5.7e-24 84.9 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEZ44360.1 - 1.5e-05 24.2 0.0 0.00076 18.6 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEZ44360.1 - 4.1e-05 23.3 0.2 0.00021 21.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEZ44360.1 - 0.00088 18.8 0.0 0.0055 16.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KEZ44360.1 - 0.05 12.2 0.4 0.086 11.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.15 KEZ44361.1 - 1e-19 70.1 0.0 1.5e-13 49.8 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme VTC PF09359.5 KEZ44362.1 - 1.5e-97 326.0 0.0 4e-97 324.6 0.0 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KEZ44362.1 - 7.5e-26 91.5 0.4 4.5e-13 49.5 0.2 2.9 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 KEZ44362.1 - 1.1e-10 41.6 0.8 1.1e-10 41.6 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF981 PF06168.6 KEZ44362.1 - 0.079 12.7 0.4 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Ank_2 PF12796.2 KEZ44363.1 - 5.5e-05 23.4 0.0 0.0002 21.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Hexokinase_2 PF03727.11 KEZ44364.1 - 2.3e-84 282.4 0.0 3.2e-84 281.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KEZ44364.1 - 4.8e-76 254.6 0.0 7.3e-76 254.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Ribophorin_I PF04597.9 KEZ44365.1 - 3.3e-147 490.5 0.1 3.7e-147 490.3 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.1 KEZ44367.1 - 4.5e-105 350.6 2.3 6.4e-105 350.1 1.6 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 KEZ44367.1 - 0.1 12.7 2.1 0.36 11.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) WW PF00397.21 KEZ44368.1 - 9.2e-10 38.2 0.1 3.1e-09 36.5 0.1 2.0 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 KEZ44368.1 - 0.028 12.9 0.1 0.042 12.4 0.1 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase PMM PF03332.8 KEZ44369.1 - 2.1e-100 334.8 0.0 2.4e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KEZ44369.1 - 0.0046 16.5 0.0 0.053 13.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 KEZ44369.1 - 0.013 14.5 0.1 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAD PF12710.2 KEZ44369.1 - 0.062 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 KEZ44369.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase Hydrolase PF00702.21 KEZ44369.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Gag_p24 PF00607.15 KEZ44369.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Na_Ca_ex PF01699.19 KEZ44370.1 - 1.4e-44 151.0 22.7 3.2e-26 91.6 8.0 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein FA_desaturase PF00487.19 KEZ44370.1 - 8.5 5.7 11.4 0.4 10.0 1.0 2.9 3 0 0 3 3 3 0 Fatty acid desaturase Cnd2 PF05786.9 KEZ44371.1 - 1.7e-214 714.5 0.3 2e-214 714.2 0.2 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 HMG_box PF00505.14 KEZ44372.1 - 4.9e-14 52.3 0.4 4.9e-14 52.3 0.3 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.25 KEZ44372.1 - 6e-11 42.3 2.3 3.4e-10 39.9 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 KEZ44372.1 - 2.2e-10 40.7 2.7 2.8e-10 40.3 0.2 2.1 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.12 KEZ44372.1 - 2.9e-06 27.0 0.6 4.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ScpA_ScpB PF02616.9 KEZ44372.1 - 0.16 11.4 1.9 0.22 11.0 1.3 1.1 1 0 0 1 1 1 0 ScpA/B protein Mis12 PF05859.7 KEZ44372.1 - 1.9 8.2 7.5 1.8 8.3 1.0 2.2 1 1 1 2 2 2 0 Mis12 protein DUF883 PF05957.8 KEZ44372.1 - 2.5 8.5 4.3 1.9 8.9 0.6 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2360 PF10152.4 KEZ44373.1 - 2.3 8.4 5.3 0.42 10.8 0.8 1.8 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) HAMP PF00672.20 KEZ44374.1 - 4.9e-48 161.1 16.3 2.8e-10 40.2 0.2 6.7 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 KEZ44374.1 - 9.3e-30 102.6 0.2 3e-29 100.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEZ44374.1 - 1.3e-27 95.9 1.0 1e-25 89.9 0.1 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KEZ44374.1 - 4.7e-18 64.9 0.6 4.7e-18 64.9 0.4 3.8 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Syntaphilin PF15290.1 KEZ44374.1 - 0.088 12.2 8.6 1 8.7 2.1 3.4 4 0 0 4 4 4 0 Golgi-localised syntaxin-1-binding clamp DUF2365 PF10157.4 KEZ44374.1 - 0.11 12.3 15.1 13 5.7 0.1 6.6 4 2 0 6 6 6 0 Uncharacterized conserved protein (DUF2365) NAAA-beta PF15508.1 KEZ44374.1 - 0.28 11.5 4.3 26 5.2 0.1 5.4 4 2 1 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TSC22 PF01166.13 KEZ44374.1 - 0.29 11.1 7.1 10 6.1 0.0 5.1 6 0 0 6 6 6 0 TSC-22/dip/bun family Pox_A_type_inc PF04508.7 KEZ44374.1 - 0.87 9.5 9.5 1 9.3 0.3 5.0 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Membr_traf_MHD PF10540.4 KEZ44375.1 - 4.2e-20 71.9 0.2 2.2e-19 69.5 0.1 2.1 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KEZ44375.1 - 1.2e-17 63.4 0.0 3.8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 KEZ44375.1 - 0.00071 17.9 0.4 0.0011 17.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF810) ArfGap PF01412.13 KEZ44376.1 - 9.7e-36 122.1 0.4 2.4e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 KEZ44376.1 - 2.3e-12 47.0 0.1 6.9e-12 45.4 0.1 1.9 1 0 0 1 1 1 1 PH domain EMP24_GP25L PF01105.19 KEZ44376.1 - 0.067 12.9 3.7 0.069 12.8 0.7 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 KEZ44377.1 - 1.6e-77 260.1 0.0 2.3e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44377.1 - 2.3e-39 135.0 0.0 3.2e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KEZ44377.1 - 9.1e-14 51.3 0.1 2.1e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KEZ44377.1 - 3.2e-12 46.0 0.0 8.7e-10 38.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KEZ44377.1 - 0.0073 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEZ44377.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KEZ44377.1 - 1.3 8.7 4.9 2.5 7.7 0.1 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family PCI PF01399.22 KEZ44378.1 - 1.4e-14 54.2 0.0 7.6e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain LuxC PF05893.9 KEZ44378.1 - 0.016 13.9 0.1 0.032 12.9 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cache_2 PF08269.6 KEZ44378.1 - 0.22 11.4 2.5 0.26 11.2 0.0 2.3 3 0 0 3 3 3 0 Cache domain ADK PF00406.17 KEZ44379.1 - 3.9e-45 153.4 0.0 5.1e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KEZ44379.1 - 2.7e-08 34.6 0.0 4.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEZ44379.1 - 1.5e-07 31.8 0.0 2.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ44379.1 - 1e-05 25.4 0.1 7.1e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KEZ44379.1 - 0.0041 16.5 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase PAS_7 PF12860.2 KEZ44379.1 - 0.099 12.6 0.0 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 PAS fold Zeta_toxin PF06414.7 KEZ44379.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.7 1 1 0 1 1 1 0 Zeta toxin Ninjurin PF04923.7 KEZ44380.1 - 0.0016 18.1 2.6 0.03 14.0 0.1 2.3 2 0 0 2 2 2 1 Ninjurin MARVEL PF01284.18 KEZ44380.1 - 0.005 16.6 8.5 0.005 16.6 5.9 1.8 1 1 1 2 2 2 1 Membrane-associating domain Peptidase_M56 PF05569.6 KEZ44380.1 - 0.054 12.4 4.3 0.08 11.8 3.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3054 PF11255.3 KEZ44380.1 - 0.063 13.1 0.3 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3054) DUF202 PF02656.10 KEZ44380.1 - 0.07 13.3 3.7 1.7 8.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF3329 PF11808.3 KEZ44380.1 - 0.14 12.2 3.8 0.14 12.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) TRIQK PF15168.1 KEZ44380.1 - 0.26 11.2 1.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF4064 PF13273.1 KEZ44380.1 - 1.7 8.8 5.3 2.1 8.5 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) GTP_EFTU PF00009.22 KEZ44382.1 - 4.3e-38 130.6 0.0 7.6e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KEZ44382.1 - 9.7e-36 121.7 0.2 2e-35 120.7 0.2 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KEZ44382.1 - 1.6e-10 40.9 0.3 3.3e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KEZ44382.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PGD PF00393.14 KEZ44383.1 - 6.9e-134 445.6 0.0 9e-134 445.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KEZ44383.1 - 2.6e-50 170.4 0.0 4e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Nsp1_C PF05064.8 KEZ44384.1 - 6.3e-41 138.6 3.4 1.4e-40 137.5 2.3 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KEZ44384.1 - 4.5e-19 68.7 196.1 3.3e-08 33.7 33.2 6.1 2 1 4 6 6 6 4 Nucleoporin FG repeat region DUF948 PF06103.6 KEZ44384.1 - 0.018 14.8 3.1 0.15 11.9 0.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.2 KEZ44384.1 - 0.24 10.6 13.8 0.59 9.4 1.5 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ERM PF00769.14 KEZ44384.1 - 1.1 8.7 12.0 4.5 6.7 8.3 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMCO5 PF14992.1 KEZ44384.1 - 2.9 6.9 7.8 4.3 6.4 5.4 1.2 1 0 0 1 1 1 0 TMCO5 family CENP-Q PF13094.1 KEZ44384.1 - 3.1 7.8 8.6 6.3 6.7 5.9 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 KEZ44384.1 - 5.4 6.8 5.6 2.2 8.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IATP PF04568.7 KEZ44385.1 - 7.8e-20 70.7 0.7 9.3e-20 70.5 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NPV_P10 PF05531.7 KEZ44385.1 - 0.14 12.4 0.5 0.18 12.0 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1003 PF06210.6 KEZ44385.1 - 0.17 11.7 3.2 0.24 11.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) HTH_32 PF13565.1 KEZ44385.1 - 0.68 10.7 2.6 0.99 10.2 1.8 1.4 1 1 0 1 1 1 0 Homeodomain-like domain HMG_CoA_synt_C PF08540.5 KEZ44388.1 - 1.6e-90 303.4 0.0 2.1e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KEZ44388.1 - 5.8e-81 270.1 0.0 8.6e-81 269.6 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal 14-3-3 PF00244.15 KEZ44389.1 - 1.3e-115 384.5 5.3 1.4e-115 384.3 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Mito_carr PF00153.22 KEZ44391.1 - 2.5e-62 206.6 0.1 1.6e-21 75.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 KEZ44392.1 - 2.2e-36 124.5 2.8 2.7e-36 124.2 1.9 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.3 KEZ44393.1 - 1.8e-24 85.8 1.7 1.8e-24 85.8 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 KEZ44393.1 - 1.4e-20 72.6 0.2 3.2e-20 71.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 KEZ44393.1 - 4.3e-11 43.4 0.8 1.2e-10 41.9 0.5 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DAHP_synth_1 PF00793.15 KEZ44394.1 - 2.1e-98 328.3 0.0 3.2e-98 327.7 0.0 1.2 1 0 0 1 1 1 1 DAHP synthetase I family Cytochrom_C1 PF02167.10 KEZ44394.1 - 5.9e-80 268.0 0.0 9.1e-80 267.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KEZ44394.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AAA PF00004.24 KEZ44395.1 - 2.4e-40 137.8 0.0 4.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ44395.1 - 4.6e-06 26.8 0.0 0.00061 19.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ44395.1 - 2.7e-05 23.9 0.1 0.00028 20.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEZ44395.1 - 0.00035 20.6 0.0 0.0031 17.5 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KEZ44395.1 - 0.00043 20.2 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KEZ44395.1 - 0.0018 17.2 0.0 0.0031 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KEZ44395.1 - 0.0043 17.8 0.1 0.014 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ44395.1 - 0.009 15.7 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KEZ44395.1 - 0.0096 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KEZ44395.1 - 0.014 15.4 0.1 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KEZ44395.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KEZ44395.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KEZ44395.1 - 0.036 13.6 0.1 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ44395.1 - 0.037 14.2 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase KaiC PF06745.8 KEZ44395.1 - 0.047 12.8 0.1 5.8 5.9 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_3 PF07726.6 KEZ44395.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KEZ44395.1 - 0.072 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 KEZ44395.1 - 0.088 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KEZ44395.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Cpn60_TCP1 PF00118.19 KEZ44396.1 - 1.7e-140 468.9 14.5 2.1e-140 468.5 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KEZ44396.1 - 0.021 14.3 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X Fungal_trans_2 PF11951.3 KEZ44397.1 - 1.3e-50 172.1 0.0 1.9e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.16 KEZ44398.1 - 1.9e-49 167.8 0.2 1e-48 165.4 0.1 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KEZ44398.1 - 4.2e-15 54.9 0.1 3.3e-07 29.9 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ING PF12998.2 KEZ44399.1 - 6.2 7.1 6.3 5.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Indigoidine_A PF04227.7 KEZ44400.1 - 2.1e-101 339.0 0.2 3.9e-101 338.1 0.2 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KEZ44400.1 - 1.4e-21 76.9 0.0 1.6e-20 73.4 0.0 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Sld5 PF05916.6 KEZ44400.1 - 3.7e-06 27.1 0.1 8.9e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 GINS complex protein HSP70 PF00012.15 KEZ44400.1 - 0.0093 13.9 0.4 0.045 11.6 0.1 2.0 2 0 0 2 2 2 1 Hsp70 protein HTH_DeoR PF08220.7 KEZ44400.1 - 0.12 11.9 0.1 0.42 10.1 0.1 1.9 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Tropomyosin PF00261.15 KEZ44402.1 - 0.088 11.8 5.1 0.13 11.3 3.6 1.1 1 0 0 1 1 1 0 Tropomyosin Transposase_22 PF02994.9 KEZ44402.1 - 0.099 11.1 0.3 0.15 10.5 0.2 1.2 1 0 0 1 1 1 0 L1 transposable element TBPIP PF07106.8 KEZ44402.1 - 0.27 10.7 2.2 0.42 10.1 1.5 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 KEZ44402.1 - 0.63 9.8 5.7 4.1 7.2 4.3 1.9 1 1 1 2 2 2 0 Tropomyosin like FAD_binding_3 PF01494.14 KEZ44404.1 - 7.9e-76 255.4 0.0 9.7e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEZ44404.1 - 2.1e-34 118.5 0.0 3.5e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KEZ44404.1 - 1.5e-07 31.7 0.0 0.0002 21.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ44404.1 - 1.8e-06 28.0 0.0 6.5e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ44404.1 - 1.4e-05 24.2 0.0 0.0023 16.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ44404.1 - 1.7e-05 23.5 0.2 4.7e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KEZ44404.1 - 3.9e-05 23.5 0.1 9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ44404.1 - 9.7e-05 22.5 1.0 0.00059 19.9 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ44404.1 - 0.00047 19.1 0.1 0.0013 17.7 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KEZ44404.1 - 0.0012 18.0 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KEZ44404.1 - 0.006 15.2 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.17 KEZ44404.1 - 0.0073 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 KEZ44404.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 KEZ44404.1 - 0.0085 16.4 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain FAD_binding_2 PF00890.19 KEZ44404.1 - 0.015 14.1 0.1 0.031 13.1 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KEZ44404.1 - 0.028 13.5 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KEZ44404.1 - 0.035 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KEZ44404.1 - 0.044 12.8 0.1 0.13 11.3 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.13 KEZ44404.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 KEZ44404.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 KEZ44404.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 KEZ44404.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 KEZ44404.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Aldedh PF00171.17 KEZ44405.1 - 1.1e-130 436.0 0.6 1.3e-130 435.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MgsA_C PF12002.3 KEZ44405.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal LuxC PF05893.9 KEZ44405.1 - 0.14 10.8 0.0 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Bromo_TP PF07524.8 KEZ44406.1 - 4.4e-10 39.1 0.0 7.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF1746 PF08508.5 KEZ44407.1 - 2.5e-34 117.6 0.9 3.9e-34 117.0 0.6 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) tRNA-synt_2d PF01409.15 KEZ44408.1 - 2.6e-85 285.5 0.0 3.5e-85 285.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KEZ44408.1 - 5.6e-06 25.3 0.4 0.00018 20.4 0.1 2.8 2 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KEZ44408.1 - 0.00083 18.9 0.0 0.0034 16.9 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) NPL4 PF05021.10 KEZ44409.1 - 3.3e-130 433.7 0.0 4.1e-130 433.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KEZ44409.1 - 6.1e-70 233.5 0.0 9.9e-70 232.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KEZ44409.1 - 0.00028 21.0 0.0 0.0018 18.5 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 CPSase_L_D2 PF02786.12 KEZ44410.1 - 3.4e-110 366.3 0.2 4.4e-84 281.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KEZ44410.1 - 5.3e-42 142.4 0.0 1.4e-41 141.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KEZ44410.1 - 2e-37 128.6 0.5 6.4e-20 71.6 0.1 2.6 3 0 0 3 3 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KEZ44410.1 - 9.5e-36 122.2 0.0 5.1e-17 61.9 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KEZ44410.1 - 2.1e-25 89.1 0.0 1e-08 34.3 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEZ44410.1 - 5.1e-21 74.7 0.1 2.9e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEZ44410.1 - 2.2e-16 59.8 1.0 1.4e-07 31.0 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KEZ44410.1 - 3.9e-08 33.0 0.1 6.8e-05 22.4 0.1 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KEZ44410.1 - 5.2e-06 26.4 0.3 0.06 13.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KEZ44410.1 - 6.4e-05 22.5 0.6 0.24 10.9 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KEZ44410.1 - 0.00011 21.5 0.1 0.093 11.9 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 KEZ44410.1 - 0.009 15.9 0.0 0.033 14.1 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain Peripla_BP_6 PF13458.1 KEZ44410.1 - 0.027 13.8 0.2 0.073 12.4 0.1 1.8 2 0 0 2 2 2 0 Periplasmic binding protein Epimerase PF01370.16 KEZ44410.1 - 0.042 13.2 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sec66 PF09802.4 KEZ44411.1 - 5.8e-78 260.6 0.5 6.9e-78 260.3 0.4 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 MSA-2c PF12238.3 KEZ44411.1 - 1.3 8.6 8.1 2.2 7.9 5.6 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Med3 PF11593.3 KEZ44411.1 - 4.1 6.5 12.3 5.3 6.1 8.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ORC3_N PF07034.6 KEZ44412.1 - 5.2e-30 104.5 4.6 3e-29 102.0 0.2 3.3 3 1 0 3 3 3 1 Origin recognition complex (ORC) subunit 3 N-terminus UPF0158 PF03682.8 KEZ44412.1 - 0.092 12.3 0.3 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) PWWP PF00855.12 KEZ44413.1 - 5.4e-16 58.5 0.9 4.9e-15 55.5 0.0 2.9 1 1 1 2 2 2 1 PWWP domain Sec63 PF02889.11 KEZ44414.1 - 6.4e-188 623.4 0.0 1.3e-101 339.9 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KEZ44414.1 - 1e-53 181.2 0.0 1.3e-30 106.1 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KEZ44414.1 - 7.6e-16 58.4 0.4 3e-08 33.7 0.0 3.3 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KEZ44414.1 - 5.7e-11 42.1 0.0 1.1e-09 37.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KEZ44414.1 - 7.6e-07 29.3 0.1 0.0036 17.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KEZ44414.1 - 4.2e-05 23.1 0.9 0.78 9.1 0.0 4.9 4 2 0 5 5 5 2 AAA-like domain T2SE PF00437.15 KEZ44414.1 - 5.1e-05 22.2 0.0 0.24 10.2 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 KEZ44414.1 - 0.00024 21.5 1.4 4.4 7.5 0.0 3.9 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 KEZ44414.1 - 0.005 16.1 0.0 1.1 8.5 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 KEZ44414.1 - 0.0058 16.3 0.0 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KEZ44414.1 - 0.0064 15.9 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family UvrD-helicase PF00580.16 KEZ44414.1 - 0.013 14.8 0.3 3.2 6.9 0.0 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 KEZ44415.1 - 3.7e-16 59.5 0.0 1.6e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KEZ44415.1 - 4.5e-13 49.1 0.0 1.1e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KEZ44415.1 - 5.1e-13 48.8 0.0 1.5e-12 47.3 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KEZ44415.1 - 4.3e-12 45.5 0.0 2.1e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEZ44415.1 - 1.1e-06 28.8 0.0 0.00055 20.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KEZ44415.1 - 1.2e-06 27.7 0.0 2.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KEZ44415.1 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ44415.1 - 1.9e-05 24.7 0.0 0.00057 19.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 KEZ44415.1 - 2.2e-05 24.1 0.0 5.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KEZ44415.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEZ44415.1 - 0.00014 21.1 0.1 0.0087 15.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEZ44415.1 - 0.0032 17.0 0.2 0.0065 16.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ44415.1 - 0.0037 18.0 0.0 0.0093 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KEZ44415.1 - 0.0042 16.6 0.0 0.0072 15.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF2075 PF09848.4 KEZ44415.1 - 0.0054 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 KEZ44415.1 - 0.0067 16.4 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ44415.1 - 0.007 16.1 0.1 0.076 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 KEZ44415.1 - 0.0088 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 KEZ44415.1 - 0.0097 15.3 0.1 0.032 13.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEZ44415.1 - 0.011 15.9 0.1 0.038 14.2 0.0 2.1 2 1 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KEZ44415.1 - 0.012 15.1 0.0 0.034 13.6 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family TIP49 PF06068.8 KEZ44415.1 - 0.013 14.2 0.0 0.31 9.7 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus TMP_2 PF06791.8 KEZ44415.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_33 PF13671.1 KEZ44415.1 - 0.016 15.1 0.0 0.063 13.1 0.0 2.1 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KEZ44415.1 - 0.024 14.2 0.0 0.36 10.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KEZ44415.1 - 0.043 13.4 0.0 0.22 11.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 KEZ44415.1 - 0.059 13.2 0.0 0.3 10.8 0.0 2.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 KEZ44415.1 - 0.072 12.5 0.1 1.6 8.1 0.0 2.4 2 1 0 3 3 3 0 AAA-like domain T2SE PF00437.15 KEZ44415.1 - 0.086 11.7 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KEZ44415.1 - 0.099 12.8 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.24 KEZ44415.1 - 0.11 11.9 0.0 2 7.9 0.0 2.6 3 0 0 3 3 3 0 DEAD/DEAH box helicase SNF2_N PF00176.18 KEZ44415.1 - 0.12 11.1 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain UQ_con PF00179.21 KEZ44416.1 - 4.5e-46 155.7 0.0 5.5e-30 103.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ44416.1 - 0.00039 20.1 0.0 0.016 14.9 0.0 2.4 2 1 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KEZ44416.1 - 0.004 17.0 0.0 1 9.2 0.0 2.6 1 1 1 2 2 2 2 RWD domain UEV PF05743.8 KEZ44416.1 - 0.015 14.9 0.0 0.051 13.2 0.0 1.9 1 0 0 1 1 1 0 UEV domain CHORD PF04968.7 KEZ44417.1 - 3.5e-26 91.2 6.5 1.7e-25 89.0 2.2 2.2 2 0 0 2 2 2 1 CHORD CS PF04969.11 KEZ44417.1 - 3.9e-11 43.3 0.1 7.2e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 CS domain Dicty_REP PF05086.7 KEZ44417.1 - 1.4 6.5 7.7 2.2 5.9 5.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 KEZ44417.1 - 3 6.9 12.3 4.4 6.4 8.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WH2 PF02205.15 KEZ44418.1 - 2.1e-09 36.6 0.6 2.1e-09 36.6 0.4 2.0 2 0 0 2 2 2 1 WH2 motif AAA_11 PF13086.1 KEZ44419.1 - 1.3e-57 195.1 0.0 2e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KEZ44419.1 - 3.6e-45 153.8 0.0 6.3e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ44419.1 - 5.9e-14 51.5 0.3 7.9e-13 47.9 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 KEZ44419.1 - 1.4e-09 37.8 0.0 6.9e-08 32.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 KEZ44419.1 - 7.3e-07 29.1 0.0 3.4e-06 27.0 0.0 2.0 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KEZ44419.1 - 1.3e-06 27.6 0.0 1e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KEZ44419.1 - 1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KEZ44419.1 - 6.1e-05 23.1 0.1 0.0014 18.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KEZ44419.1 - 0.00024 20.6 0.0 0.0029 17.1 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 KEZ44419.1 - 0.00047 19.7 0.0 0.78 9.2 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KEZ44419.1 - 0.00067 18.6 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.9 KEZ44419.1 - 0.00067 19.3 0.0 0.031 13.8 0.0 2.3 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 KEZ44419.1 - 0.0023 17.9 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 KEZ44419.1 - 0.003 17.0 0.0 0.041 13.3 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Flavi_DEAD PF07652.9 KEZ44419.1 - 0.0042 16.8 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.1 KEZ44419.1 - 0.0057 16.0 0.1 0.038 13.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain 4HB_MCP_1 PF12729.2 KEZ44419.1 - 0.0057 16.0 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction IstB_IS21 PF01695.12 KEZ44419.1 - 0.0078 15.6 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 KEZ44419.1 - 0.0091 14.6 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 KEZ44419.1 - 0.014 15.2 0.0 0.046 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KEZ44419.1 - 0.015 14.5 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Zot PF05707.7 KEZ44419.1 - 0.015 14.7 0.0 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_5 PF07728.9 KEZ44419.1 - 0.018 14.7 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KEZ44419.1 - 0.024 14.8 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KEZ44419.1 - 0.04 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KEZ44419.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF202 PF02656.10 KEZ44420.1 - 1.8e-24 85.7 1.7 1.8e-24 85.7 1.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cytochrom_B_N PF00033.14 KEZ44420.1 - 0.27 10.5 3.1 0.41 9.9 2.1 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB zf-C2H2 PF00096.21 KEZ44421.1 - 1.9e-12 46.7 11.4 2.3e-06 27.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ44421.1 - 2e-10 40.2 10.1 0.00012 22.1 3.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ44421.1 - 2.2e-08 33.9 12.4 5.7e-07 29.5 3.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KEZ44421.1 - 1.5e-06 28.1 5.6 0.00029 20.8 0.7 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ44421.1 - 1.7e-06 28.0 4.3 0.0001 22.3 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KEZ44421.1 - 0.00072 19.3 7.8 0.019 14.8 0.2 2.9 2 1 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 KEZ44421.1 - 1.2 8.9 6.8 1.4 8.7 2.3 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 KEZ44421.1 - 6.2 6.6 7.2 9.9 5.9 1.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type COesterase PF00135.23 KEZ44422.1 - 2.9e-78 263.9 0.0 3.4e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ44422.1 - 1.8e-05 24.4 0.0 6.2e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PKD PF00801.15 KEZ44422.1 - 0.059 13.1 1.2 0.15 11.8 0.9 1.6 1 0 0 1 1 1 0 PKD domain Abhydrolase_5 PF12695.2 KEZ44422.1 - 0.067 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 KEZ44423.1 - 3.9e-06 26.4 0.2 8.1e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ44423.1 - 0.0034 16.9 0.0 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain Fungal_trans_2 PF11951.3 KEZ44424.1 - 3e-74 249.9 0.0 3.7e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ44424.1 - 1.6e-06 27.9 9.4 2.5e-06 27.2 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.12 KEZ44425.1 - 9.9e-06 25.3 0.0 3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.24 KEZ44425.1 - 4e-05 23.7 0.0 7.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.25 KEZ44425.1 - 0.0036 17.4 0.0 0.0081 16.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 KEZ44425.1 - 0.096 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_9 PF15410.1 KEZ44425.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Sod_Fe_C PF02777.13 KEZ44426.1 - 7.1e-11 41.8 0.0 0.0003 20.5 0.0 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KEZ44426.1 - 0.00021 21.4 0.1 0.00031 20.9 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3661 PF12400.3 KEZ44427.1 - 6.7e-42 142.6 2.7 1.1e-41 141.9 1.9 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein APH PF01636.18 KEZ44428.1 - 2.3e-10 40.6 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ44428.1 - 2.2e-05 24.1 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KEZ44428.1 - 0.00059 19.0 0.0 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 KEZ44428.1 - 0.0067 15.4 0.0 0.017 14.1 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase LRR_4 PF12799.2 KEZ44429.1 - 0.024 14.2 1.1 11 5.7 0.7 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) adh_short PF00106.20 KEZ44430.1 - 1.9e-18 66.9 0.0 7.4e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ44430.1 - 2.4e-08 33.8 0.1 5.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ44430.1 - 7.3e-05 22.6 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 KEZ44430.1 - 0.00023 20.1 0.0 0.00035 19.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3HCDH_N PF02737.13 KEZ44430.1 - 0.0022 17.6 0.1 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KEZ44430.1 - 0.0028 17.1 0.1 0.004 16.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEZ44430.1 - 0.0044 17.0 0.2 0.015 15.2 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding Flavodoxin_1 PF00258.20 KEZ44430.1 - 0.0058 16.6 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin 2-Hacid_dh_C PF02826.14 KEZ44430.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KEZ44430.1 - 0.023 15.1 0.1 0.56 10.6 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KEZ44430.1 - 0.025 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 KEZ44430.1 - 0.064 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans_2 PF11951.3 KEZ44431.1 - 0.00016 20.4 1.4 0.00024 19.8 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.12 KEZ44431.1 - 0.13 11.8 0.3 0.18 11.4 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Glyco_hydro_14 PF01373.12 KEZ44431.1 - 0.16 10.6 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 RCR PF12273.3 KEZ44432.1 - 3.4e-15 56.7 17.8 6.1e-15 55.9 12.3 1.4 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF2668 PF10873.3 KEZ44432.1 - 0.0011 19.1 2.2 0.0019 18.3 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) Rhabdo_glycop PF00974.13 KEZ44432.1 - 4.1 5.5 5.5 0.33 9.1 0.7 1.3 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein FAA_hydrolase PF01557.13 KEZ44434.1 - 2.2e-52 177.6 0.0 2.8e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ctr PF04145.10 KEZ44435.1 - 1.6e-34 119.0 12.3 1.4e-33 115.9 8.5 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.15 KEZ44435.1 - 0.012 15.0 0.3 0.014 14.8 0.2 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 NUDIX PF00293.23 KEZ44436.1 - 1.7e-13 50.3 0.0 4e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain EXS PF03124.9 KEZ44437.1 - 9.6e-98 327.3 3.9 1.1e-97 327.2 2.7 1.0 1 0 0 1 1 1 1 EXS family zf-LYAR PF08790.6 KEZ44438.1 - 1.8e-13 49.9 4.2 1.8e-13 49.9 2.9 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger LacI PF00356.16 KEZ44438.1 - 0.049 13.2 0.2 0.09 12.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Abhydrolase_5 PF12695.2 KEZ44439.1 - 4.4e-23 81.6 0.0 6.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ44439.1 - 1.7e-17 64.0 0.2 9.5e-16 58.3 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ44439.1 - 7.6e-07 28.9 0.1 0.00019 21.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KEZ44439.1 - 3.5e-06 26.6 0.0 0.0032 16.9 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 KEZ44439.1 - 7.9e-05 21.2 0.0 0.16 10.4 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 KEZ44439.1 - 0.00065 19.2 0.0 0.0018 17.7 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 KEZ44439.1 - 0.00072 18.8 0.0 0.0054 15.9 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.7 KEZ44439.1 - 0.0012 17.6 0.1 0.0017 17.1 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.8 KEZ44439.1 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KEZ44439.1 - 0.0045 16.7 0.0 0.22 11.2 0.0 2.3 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KEZ44439.1 - 0.032 13.4 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 KEZ44439.1 - 0.073 12.4 0.0 5.9 6.2 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KEZ44439.1 - 0.074 12.9 0.2 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 Putative lysophospholipase R3H PF01424.17 KEZ44440.1 - 3.6e-13 49.0 0.0 8.2e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain Dehyd-heme_bind PF09098.5 KEZ44440.1 - 0.075 12.4 0.1 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding WSC PF01822.14 KEZ44442.1 - 6.4e-90 295.2 74.4 5e-20 71.2 10.3 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 KEZ44442.1 - 2.1e-29 102.3 0.0 1.9e-27 95.9 0.0 3.2 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KEZ44442.1 - 8.1e-23 80.3 0.0 1.7e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Dopey_N PF04118.9 KEZ44444.1 - 6.6e-121 402.8 0.0 3.8e-119 397.0 0.0 2.6 2 0 0 2 2 2 2 Dopey, N-terminal DUF3867 PF12983.2 KEZ44444.1 - 0.77 9.7 0.0 1.4 8.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) Methyltransf_15 PF09445.5 KEZ44445.1 - 1.6e-41 141.5 0.0 2.3e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KEZ44445.1 - 1.2e-06 28.4 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KEZ44445.1 - 4.7e-06 26.3 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 KEZ44445.1 - 5.1e-05 22.7 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 KEZ44445.1 - 0.00018 22.0 0.0 0.00026 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KEZ44445.1 - 0.00028 20.5 0.0 0.00058 19.4 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 KEZ44445.1 - 0.0048 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KEZ44445.1 - 0.027 13.1 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 KEZ44445.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DNA_methylase PF00145.12 KEZ44445.1 - 0.072 12.1 0.1 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_5 PF01795.14 KEZ44445.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family DUF2093 PF09866.4 KEZ44445.1 - 1.2 8.3 3.7 1.3 8.2 0.5 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2093) GRASP55_65 PF04495.9 KEZ44446.1 - 1.9e-48 163.9 0.0 1e-47 161.5 0.0 1.8 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain DAD PF02109.11 KEZ44447.1 - 8.1e-46 154.7 2.2 9.8e-46 154.4 1.5 1.0 1 0 0 1 1 1 1 DAD family Tmemb_14 PF03647.8 KEZ44448.1 - 9.8e-25 86.7 5.8 1.2e-24 86.5 4.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 KEZ44448.1 - 0.078 13.2 0.3 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) Cmc1 PF08583.5 KEZ44449.1 - 2.4e-14 52.8 2.2 2.9e-14 52.5 1.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Prefoldin_2 PF01920.15 KEZ44450.1 - 8.1e-23 80.2 8.0 9.3e-23 80.0 5.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KEZ44450.1 - 0.014 15.0 5.6 0.36 10.4 3.9 2.1 1 1 0 1 1 1 0 Prefoldin subunit FliJ PF02050.11 KEZ44450.1 - 0.017 15.1 6.0 0.3 11.1 1.0 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF148 PF02520.12 KEZ44450.1 - 0.024 14.4 4.5 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 UBN2 PF14223.1 KEZ44450.1 - 0.029 14.1 1.0 0.21 11.3 0.1 2.0 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Tho2 PF11262.3 KEZ44450.1 - 0.039 12.9 4.1 0.95 8.4 1.1 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 KaiC PF06745.8 KEZ44450.1 - 0.041 12.9 0.3 0.71 8.9 0.0 2.0 1 1 1 2 2 2 0 KaiC DASH_Dad3 PF08656.5 KEZ44450.1 - 0.059 13.0 2.4 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 RUN PF02759.14 KEZ44450.1 - 0.068 12.9 0.1 0.084 12.6 0.1 1.2 1 0 0 1 1 1 0 RUN domain Syntaxin PF00804.20 KEZ44450.1 - 0.072 13.2 0.9 0.12 12.5 0.7 1.4 1 1 0 1 1 1 0 Syntaxin Mnd1 PF03962.10 KEZ44450.1 - 0.073 12.7 2.4 0.13 11.9 1.6 1.4 1 1 0 1 1 1 0 Mnd1 family STAT_alpha PF01017.15 KEZ44450.1 - 0.097 12.3 3.1 0.13 11.9 2.1 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Syntaxin-6_N PF09177.6 KEZ44450.1 - 0.15 12.4 1.7 6 7.3 0.0 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.4 KEZ44450.1 - 0.2 11.8 4.2 0.23 11.6 0.4 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cytochrom_B562 PF07361.6 KEZ44450.1 - 0.32 11.4 4.9 3.2 8.2 0.7 2.1 2 0 0 2 2 2 0 Cytochrome b562 Seryl_tRNA_N PF02403.17 KEZ44450.1 - 0.36 10.8 6.4 0.49 10.4 0.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 KEZ44450.1 - 0.38 9.9 8.5 1.7 7.8 5.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2205 PF10224.4 KEZ44450.1 - 1.5 8.4 5.1 7.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CBFD_NFYB_HMF PF00808.18 KEZ44451.1 - 1.6e-21 76.1 4.0 6.8e-20 70.8 2.8 2.2 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEZ44451.1 - 0.011 15.8 0.1 0.25 11.4 0.1 2.2 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Peptidase_C1_2 PF03051.10 KEZ44451.1 - 0.035 12.6 0.0 0.044 12.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Kelch_3 PF13415.1 KEZ44452.1 - 1.9e-28 97.9 9.1 4.3e-10 39.4 0.0 6.8 8 0 0 8 8 8 4 Galactose oxidase, central domain DUF4110 PF13422.1 KEZ44452.1 - 2.6e-25 88.0 0.5 2.6e-25 88.0 0.4 3.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 KEZ44452.1 - 3.1e-23 81.2 14.7 1.7e-07 30.9 0.0 7.1 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KEZ44452.1 - 4.1e-22 77.7 0.4 4e-07 29.8 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 KEZ44452.1 - 1.6e-17 62.4 2.6 0.00065 19.3 0.0 5.9 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 KEZ44452.1 - 7.1e-15 54.4 1.6 0.014 15.5 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KEZ44452.1 - 2.4e-10 39.7 0.0 0.0028 17.1 0.0 5.2 5 0 0 5 5 5 2 Kelch motif TFIIF_alpha PF05793.7 KEZ44452.1 - 3.9 5.7 27.3 0.08 11.2 6.6 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Thioredoxin PF00085.15 KEZ44454.1 - 1e-61 205.0 4.0 3e-30 103.9 0.0 4.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KEZ44454.1 - 8.4e-53 178.9 0.2 2.2e-38 131.8 0.0 3.7 2 1 1 3 3 3 3 Thioredoxin-like domain WLM PF08325.5 KEZ44454.1 - 1.4e-50 171.8 0.0 4.4e-50 170.1 0.0 1.9 1 1 0 1 1 1 1 WLM domain Thioredoxin_7 PF13899.1 KEZ44454.1 - 1.7e-10 40.7 0.0 0.00087 19.2 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KEZ44454.1 - 3.6e-09 36.6 0.0 0.0012 18.9 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KEZ44454.1 - 1.1e-08 35.2 2.2 0.0027 17.8 0.0 3.9 3 2 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.5 KEZ44454.1 - 4e-08 32.9 2.0 0.027 13.9 0.0 3.6 3 0 0 3 3 3 3 Redoxin Calsequestrin PF01216.12 KEZ44454.1 - 4.4e-08 32.3 0.1 8.1e-08 31.4 0.1 1.4 1 0 0 1 1 1 1 Calsequestrin DUF45 PF01863.12 KEZ44454.1 - 9.3e-08 32.1 0.2 3.3e-07 30.2 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF45 AhpC-TSA PF00578.16 KEZ44454.1 - 8.3e-07 28.7 2.2 0.0035 17.0 0.0 3.3 4 0 0 4 4 4 2 AhpC/TSA family ERp29_N PF07912.8 KEZ44454.1 - 0.017 15.0 0.1 5.9 6.8 0.0 3.4 3 1 0 3 3 3 0 ERp29, N-terminal domain Herpes_pp85 PF04637.7 KEZ44454.1 - 0.11 10.7 1.9 0.18 10.0 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Thioredoxin_4 PF13462.1 KEZ44454.1 - 0.11 12.4 3.7 5.7 6.9 0.4 3.5 2 1 0 2 2 2 0 Thioredoxin Enolase_C PF00113.17 KEZ44455.1 - 5.7e-153 508.0 0.0 7.7e-153 507.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KEZ44455.1 - 2.6e-58 195.6 0.1 4.5e-58 194.8 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 KEZ44455.1 - 0.016 15.7 0.0 0.032 14.7 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 KEZ44455.1 - 0.02 13.8 0.2 0.66 8.8 0.0 2.7 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus Mad3_BUB1_I PF08311.7 KEZ44456.1 - 5.6e-41 139.2 0.5 9.3e-41 138.5 0.4 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KEZ44456.1 - 8.2e-13 48.0 0.0 1.8e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44456.1 - 0.0034 16.4 0.0 0.012 14.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 KEZ44456.1 - 0.0065 16.3 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 AP_endonuc_2 PF01261.19 KEZ44457.1 - 1.1e-31 109.7 0.3 1.7e-31 109.2 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAGAT PF03982.8 KEZ44458.1 - 3.2e-92 308.3 0.0 4.2e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase zf-H2C2_2 PF13465.1 KEZ44459.1 - 2.5e-17 62.2 22.3 7.8e-09 35.3 2.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ44459.1 - 3.8e-11 42.6 24.7 0.0021 18.2 4.8 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ44459.1 - 1.5e-08 34.4 19.0 0.0065 16.7 3.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KEZ44459.1 - 0.0023 17.7 11.9 0.6 10.0 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger GAGA PF09237.6 KEZ44459.1 - 0.0043 16.6 6.2 2.8 7.6 0.1 3.9 2 1 2 4 4 4 1 GAGA factor Rpr2 PF04032.11 KEZ44459.1 - 0.056 13.3 0.5 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_Tnp_IS1595 PF12760.2 KEZ44459.1 - 0.058 13.2 7.8 0.18 11.6 2.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF848 PF05852.6 KEZ44459.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) zf-C2H2_jaz PF12171.3 KEZ44459.1 - 0.15 12.2 10.2 0.11 12.6 1.3 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KEZ44459.1 - 0.31 11.0 8.9 2.4 8.1 3.8 3.0 2 1 0 2 2 2 0 Zinc ribbon domain zf-XS PF03470.9 KEZ44459.1 - 0.89 9.6 6.4 7.2 6.7 0.3 3.0 2 1 1 3 3 3 0 XS zinc finger domain zf-CHY PF05495.7 KEZ44459.1 - 2.1 8.5 8.5 4 7.6 5.9 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-CHCC PF10276.4 KEZ44459.1 - 2.5 8.0 6.6 11 5.9 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-met PF12874.2 KEZ44459.1 - 4.4 7.6 14.7 0.41 10.9 1.7 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type SUN PF03856.8 KEZ44460.1 - 6.1e-90 300.8 10.2 8e-90 300.4 7.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Trypan_PARP PF05887.6 KEZ44460.1 - 0.00027 20.7 12.9 0.00047 19.9 9.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 KEZ44460.1 - 9.1 5.3 22.8 15 4.6 15.8 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MFS_1 PF07690.11 KEZ44461.1 - 9.3e-08 31.1 26.5 9.3e-08 31.1 18.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ44461.1 - 5.4e-05 21.9 3.5 5.4e-05 21.9 2.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter UDPGP PF01704.13 KEZ44462.1 - 1e-183 610.6 0.2 1.2e-183 610.3 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3605 PF12239.3 KEZ44463.1 - 8.3e-54 181.7 0.0 1e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.13 KEZ44464.1 - 1.7e-20 73.2 0.0 9.6e-12 45.0 0.0 2.6 2 1 0 2 2 2 2 Dihydroneopterin aldolase SKG6 PF08693.5 KEZ44465.1 - 6.3e-05 22.2 0.3 6.3e-05 22.2 0.2 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Rax2 PF12768.2 KEZ44465.1 - 0.025 13.7 0.0 0.074 12.2 0.0 1.6 1 1 0 1 1 1 0 Cortical protein marker for cell polarity NOB1_Zn_bind PF08772.6 KEZ44465.1 - 0.13 12.1 0.5 0.33 10.8 0.3 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-IS66 PF13005.2 KEZ44465.1 - 0.35 10.8 1.9 0.43 10.5 0.2 1.9 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 PAP1 PF08601.5 KEZ44465.1 - 3.3 7.2 10.1 0.26 10.9 3.7 1.5 2 0 0 2 2 2 0 Transcription factor PAP1 SHS2_Rpb7-N PF03876.12 KEZ44466.1 - 2.1e-13 50.1 0.0 3.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KEZ44466.1 - 3.7e-12 46.1 0.0 5.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KEZ44466.1 - 0.03 14.4 0.1 0.11 12.6 0.0 1.8 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 DUF962 PF06127.6 KEZ44467.1 - 1.5e-26 92.1 0.7 1.9e-26 91.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF3852 PF12963.2 KEZ44467.1 - 0.16 12.0 1.4 0.47 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) AAA_22 PF13401.1 KEZ44469.1 - 1.2e-12 48.0 0.1 2.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ44469.1 - 2.1e-11 44.1 0.1 6.2e-10 39.3 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KEZ44469.1 - 3.5e-11 43.4 0.1 8.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KEZ44469.1 - 0.00019 21.3 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEZ44469.1 - 0.00026 19.9 0.0 0.0005 19.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Cdc6_C PF09079.6 KEZ44469.1 - 0.00039 20.0 0.0 0.0025 17.4 0.0 2.4 2 0 0 2 2 2 1 CDC6, C terminal AAA_5 PF07728.9 KEZ44469.1 - 0.00099 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KEZ44469.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase KAP_NTPase PF07693.9 KEZ44469.1 - 0.006 15.6 0.2 0.018 14.0 0.0 1.8 2 1 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 KEZ44469.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ44469.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KEZ44469.1 - 0.018 14.7 0.1 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_32 PF13654.1 KEZ44469.1 - 0.021 13.4 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KEZ44469.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Rad17 PF03215.10 KEZ44469.1 - 0.025 13.2 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 KEZ44469.1 - 0.026 14.7 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 KEZ44469.1 - 0.035 13.0 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KEZ44469.1 - 0.044 13.5 0.1 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Rrf2 PF02082.15 KEZ44469.1 - 0.057 13.5 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DEAD PF00270.24 KEZ44469.1 - 0.062 12.7 0.9 0.26 10.7 0.7 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase RNA12 PF10443.4 KEZ44469.1 - 0.093 11.2 0.1 0.21 10.0 0.0 1.6 2 0 0 2 2 2 0 RNA12 protein AAA_2 PF07724.9 KEZ44469.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Fanconi_A PF03511.9 KEZ44469.1 - 0.14 11.9 0.4 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Fanconi anaemia group A protein Arrestin_N PF00339.24 KEZ44470.1 - 2.3e-15 56.7 0.0 7.1e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ComGG PF14173.1 KEZ44470.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 ComG operon protein 7 DUF836 PF05768.9 KEZ44471.1 - 1e-15 57.7 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 KEZ44471.1 - 0.00088 19.2 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KEZ44471.1 - 0.012 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain FlbT PF07378.6 KEZ44471.1 - 0.06 13.2 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Flagellar protein FlbT Fcf1 PF04900.7 KEZ44472.1 - 3.2e-31 107.4 0.0 6.3e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Fcf1 Dsh_C PF12316.3 KEZ44472.1 - 1.1 9.3 6.6 94 3.0 0.0 2.0 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal PP2C_2 PF13672.1 KEZ44473.1 - 0.00017 21.0 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 KEZ44473.1 - 0.00082 18.8 0.0 0.79 9.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 KEZ44473.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PH PF00169.24 KEZ44474.1 - 2e-05 24.7 0.0 0.00034 20.7 0.0 2.7 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 KEZ44474.1 - 0.063 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_S9_N PF02897.10 KEZ44474.1 - 0.12 10.9 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Pkinase PF00069.20 KEZ44475.1 - 2.5e-63 213.6 0.0 3.9e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44475.1 - 1.8e-29 102.5 0.0 3.5e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KEZ44475.1 - 7e-12 45.2 0.1 1.3e-08 34.7 0.1 2.8 2 0 0 2 2 2 2 FHA domain YrbL-PhoP_reg PF10707.4 KEZ44475.1 - 0.0074 15.6 0.0 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KEZ44475.1 - 0.008 15.2 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEZ44475.1 - 0.069 12.1 0.0 0.23 10.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like CRT10 PF08728.5 KEZ44476.1 - 6.6e-15 54.1 0.0 3.8e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 CRT10 TFIIA PF03153.8 KEZ44476.1 - 0.21 11.4 17.7 0.33 10.7 12.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 KEZ44476.1 - 0.31 8.8 29.0 0.47 8.3 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KEZ44476.1 - 3.3 5.6 19.3 4.9 5.0 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 KEZ44476.1 - 8.5 5.5 20.9 19 4.3 14.5 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2201_N PF13203.1 KEZ44476.1 - 8.9 5.3 8.4 19 4.3 5.8 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Ammonium_transp PF00909.16 KEZ44477.1 - 1.2e-115 386.1 30.9 1.4e-115 385.9 21.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_2 PF00328.17 KEZ44478.1 - 8.8e-38 130.5 0.0 1.1e-37 130.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3357 PF11837.3 KEZ44478.1 - 0.068 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TauD PF02668.11 KEZ44479.1 - 4.1e-23 82.3 0.1 5.5e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEZ44479.1 - 0.0037 16.2 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 CsiD Ribul_P_3_epim PF00834.14 KEZ44479.1 - 0.13 11.3 0.1 5.4 6.0 0.0 2.1 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family EMP24_GP25L PF01105.19 KEZ44482.1 - 7.3e-44 149.6 0.0 8.5e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 KEZ44482.1 - 0.06 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Dioxygenase Arf PF00025.16 KEZ44483.1 - 2.3e-79 264.6 0.2 2.7e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEZ44483.1 - 1.5e-14 53.5 0.0 1.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KEZ44483.1 - 2.6e-13 49.6 0.0 2.9e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KEZ44483.1 - 4.5e-12 45.3 1.7 6.2e-09 35.0 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KEZ44483.1 - 2.6e-11 43.1 0.0 3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEZ44483.1 - 5.8e-09 36.4 0.0 8.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEZ44483.1 - 3.2e-06 27.0 0.0 4.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KEZ44483.1 - 0.0068 15.5 0.5 0.019 14.0 0.1 1.7 1 1 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KEZ44483.1 - 0.022 14.2 0.1 0.17 11.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEZ44483.1 - 0.057 13.2 0.2 0.12 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain WLM PF08325.5 KEZ44484.1 - 0.03 14.1 1.4 0.042 13.7 0.0 1.7 2 0 0 2 2 2 0 WLM domain zf-C2H2 PF00096.21 KEZ44485.1 - 1.8e-21 75.1 28.5 7.4e-05 22.8 0.4 7.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEZ44485.1 - 1.7e-15 56.4 38.7 2.6e-07 30.5 0.2 6.5 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 KEZ44485.1 - 2.1e-08 33.7 15.1 0.0062 16.4 0.5 5.0 3 1 1 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ44485.1 - 5.4e-08 32.7 15.7 0.0037 17.3 0.5 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KEZ44485.1 - 4.3e-07 29.8 55.5 0.0069 16.6 0.4 8.4 9 0 0 9 9 9 5 C2H2-type zinc finger zf-met PF12874.2 KEZ44485.1 - 0.0011 19.0 13.7 0.24 11.6 0.1 5.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KEZ44485.1 - 1.9 8.6 19.9 1.5 8.9 0.8 4.4 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) Ribosomal_L29 PF00831.18 KEZ44486.1 - 6.3e-18 64.2 2.4 6.3e-18 64.2 1.7 1.7 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 KEZ44486.1 - 0.054 13.7 1.3 0.073 13.3 0.9 1.3 1 1 0 1 1 1 0 Ribosomal protein S9/S16 SPATA24 PF15175.1 KEZ44486.1 - 0.077 12.6 2.5 0.09 12.4 1.8 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Phe_tRNA-synt_N PF02912.13 KEZ44486.1 - 0.085 12.5 2.2 0.12 12.1 0.3 2.1 2 1 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain AICARFT_IMPCHas PF01808.13 KEZ44487.1 - 1.2e-107 359.7 0.0 1.5e-107 359.3 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KEZ44487.1 - 4.2e-25 87.4 0.0 8.4e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain V-SNARE_C PF12352.3 KEZ44488.1 - 5.9e-14 51.8 5.3 4.9e-13 48.9 0.0 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus STAT_alpha PF01017.15 KEZ44488.1 - 0.06 13.0 4.0 0.38 10.4 1.2 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain IncA PF04156.9 KEZ44488.1 - 0.068 12.7 7.6 0.13 11.8 5.3 1.4 1 0 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.1 KEZ44488.1 - 0.16 11.9 9.5 0.19 11.7 0.5 3.0 2 1 1 3 3 3 0 Syntaxin-like protein GOLGA2L5 PF15070.1 KEZ44488.1 - 0.63 8.4 9.1 0.49 8.8 5.2 1.5 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 FTA4 PF13093.1 KEZ44488.1 - 0.63 9.4 8.3 3.2 7.1 1.6 2.3 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF342 PF03961.8 KEZ44488.1 - 3.4 5.9 4.8 3.6 5.9 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 KEZ44488.1 - 3.7 7.9 7.8 2 8.7 2.9 2.3 1 1 1 2 2 2 0 Snapin/Pallidin APG6 PF04111.7 KEZ44488.1 - 6.1 5.8 8.4 3.7 6.4 4.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ATP-synt_10 PF05176.9 KEZ44489.1 - 5e-83 278.2 0.0 6.9e-83 277.7 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.18 KEZ44490.1 - 1.1e-74 250.6 0.4 1.9e-74 249.7 0.3 1.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEZ44490.1 - 2.5e-18 65.4 0.1 5.2e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEZ44490.1 - 6.1e-13 48.1 0.0 1.9e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KEZ44490.1 - 0.033 13.8 0.0 0.66 9.6 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like AAA_17 PF13207.1 KEZ44491.1 - 1.4e-11 45.2 0.0 1.9e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KEZ44491.1 - 1e-10 41.7 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 KEZ44491.1 - 3.2e-10 40.0 0.0 5.5e-10 39.2 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KEZ44491.1 - 4.9e-09 36.5 0.0 1.1e-08 35.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KEZ44491.1 - 0.0015 17.3 0.0 0.0022 16.7 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KEZ44491.1 - 0.002 18.2 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ44491.1 - 0.0026 17.7 0.1 0.0059 16.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KEZ44491.1 - 0.0046 17.1 0.1 0.022 14.9 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ44491.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEZ44491.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KEZ44491.1 - 0.022 14.6 0.0 0.041 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ44491.1 - 0.033 14.3 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KEZ44491.1 - 0.035 13.6 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KEZ44491.1 - 0.05 13.2 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.1 KEZ44491.1 - 0.051 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KEZ44491.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KEZ44491.1 - 0.083 12.0 0.0 0.2 10.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KEZ44491.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DNA_pol3_delta2 PF13177.1 KEZ44491.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Herpes_Helicase PF02689.9 KEZ44491.1 - 0.16 9.7 0.0 0.2 9.3 0.0 1.1 1 0 0 1 1 1 0 Helicase Peptidase_M49 PF03571.10 KEZ44492.1 - 8e-228 756.9 0.0 9.5e-228 756.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.15 KEZ44492.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 2C_adapt PF08793.5 KEZ44492.1 - 0.15 11.9 0.2 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain Ribosomal_L6e PF01159.14 KEZ44493.1 - 3.5e-38 130.1 0.5 6.3e-38 129.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e HCNGP PF07818.8 KEZ44494.1 - 1.7e-25 88.8 0.0 2.5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 HCNGP-like protein DUF3712 PF12505.3 KEZ44495.1 - 5.6e-22 78.0 3.2 1.3e-21 76.8 2.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF805 PF05656.9 KEZ44495.1 - 0.059 13.2 0.1 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) FMN_dh PF01070.13 KEZ44496.1 - 5e-103 344.6 0.0 6.2e-103 344.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KEZ44496.1 - 8.6e-20 70.3 0.0 1.9e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KEZ44496.1 - 9.6e-08 31.3 0.1 1.5e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEZ44496.1 - 2.2e-07 30.1 0.1 0.00042 19.3 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 KEZ44496.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.16 KEZ44496.1 - 0.016 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 KEZ44496.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.14 KEZ44496.1 - 0.044 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family NMO PF03060.10 KEZ44496.1 - 0.073 12.2 2.0 0.2 10.8 0.1 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase Lipase_GDSL_2 PF13472.1 KEZ44497.1 - 1.1e-19 71.2 0.0 3.6e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ44497.1 - 1.2e-07 31.7 0.0 1.5e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HSCB_C PF07743.8 KEZ44497.1 - 3.2e-07 30.7 5.4 3.2e-07 30.7 3.7 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KEZ44497.1 - 9.5e-07 28.4 0.0 2.6e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain PCI PF01399.22 KEZ44498.1 - 7.7e-11 42.2 0.0 1.1e-09 38.4 0.0 2.8 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.4 KEZ44498.1 - 7.3e-05 22.2 0.1 0.00017 21.0 0.0 1.7 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_12 PF13424.1 KEZ44498.1 - 0.003 17.4 0.8 0.16 11.9 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat LRR_4 PF12799.2 KEZ44499.1 - 0.00075 19.0 7.7 0.072 12.7 1.9 3.6 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KEZ44499.1 - 0.00089 18.9 0.3 0.0023 17.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KEZ44499.1 - 0.25 11.1 13.7 0.027 14.2 1.5 3.8 3 1 0 4 4 4 0 Leucine rich repeat SNF2_N PF00176.18 KEZ44500.1 - 4.8e-32 110.9 0.0 1.7e-29 102.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ44500.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ44500.1 - 0.0059 16.4 0.0 1.5 8.6 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DUF4243 PF14027.1 KEZ44501.1 - 8.6e-80 268.6 0.2 1.8e-79 267.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Rad17 PF03215.10 KEZ44501.1 - 1.3e-49 169.3 0.0 1.8e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KEZ44501.1 - 0.00033 20.8 0.0 0.0015 18.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEZ44501.1 - 0.003 17.2 0.2 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KEZ44501.1 - 0.034 14.1 0.0 0.097 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 KEZ44501.1 - 0.039 14.7 0.0 0.13 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEZ44501.1 - 0.047 13.8 0.4 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEZ44501.1 - 0.097 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KEZ44501.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 KEZ44501.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UPF0079 PF02367.12 KEZ44501.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF3885 PF13021.1 KEZ44501.1 - 0.53 10.0 3.4 0.78 9.4 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Herpes_Helicase PF02689.9 KEZ44501.1 - 0.59 7.8 0.0 0.92 7.1 0.0 1.2 1 0 0 1 1 1 0 Helicase DUF605 PF04652.11 KEZ44503.1 - 0.055 12.8 21.1 0.083 12.2 14.6 1.2 1 0 0 1 1 1 0 Vta1 like WWbp PF10349.4 KEZ44503.1 - 0.73 10.7 8.0 1.5 9.7 5.2 1.8 2 0 0 2 2 2 0 WW-domain ligand protein Apt1 PF10351.4 KEZ44503.1 - 2.6 6.7 10.3 4.3 6.0 7.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ppx-GppA PF02541.11 KEZ44504.1 - 1.6e-26 93.2 0.0 2.9e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family O-FucT PF10250.4 KEZ44504.1 - 0.0021 17.2 0.0 0.0044 16.1 0.0 1.5 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase BTB PF00651.26 KEZ44505.1 - 0.0018 18.2 0.0 0.0055 16.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Oxidored_FMN PF00724.15 KEZ44506.1 - 6.9e-72 242.2 0.0 1.6e-71 241.1 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SUI1 PF01253.17 KEZ44507.1 - 1.1e-10 41.1 3.2 5.3e-10 38.9 0.3 2.5 2 1 0 2 2 2 1 Translation initiation factor SUI1 Dermcidin PF15291.1 KEZ44507.1 - 0.037 14.2 2.1 0.049 13.8 1.4 1.2 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide SYCE1 PF15233.1 KEZ44507.1 - 0.97 9.3 4.8 2 8.3 3.3 1.5 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF4230 PF14014.1 KEZ44507.1 - 1.5 8.6 7.4 18 5.1 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4230) Nbl1_Borealin_N PF10444.4 KEZ44508.1 - 2.4e-22 78.0 4.2 4.2e-22 77.2 2.9 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 KEZ44509.1 - 1.7e-17 64.0 0.1 2.2e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEZ44509.1 - 3.8e-08 33.2 0.3 5e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KEZ44509.1 - 4.4e-08 32.9 0.0 6.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KEZ44509.1 - 0.0015 17.9 1.0 0.005 16.2 0.7 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Anp1 PF03452.9 KEZ44509.1 - 0.082 12.0 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Anp1 U79_P34 PF03064.11 KEZ44509.1 - 5.2 6.5 11.0 36 3.7 6.1 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Sybindin PF04099.7 KEZ44510.1 - 2.7e-53 179.5 0.0 3e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KEZ44510.1 - 3.7e-08 33.2 0.0 7.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region EGL-1 PF11430.3 KEZ44510.1 - 0.095 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 RNA_pol_Rpb4 PF03874.11 KEZ44511.1 - 2.5e-27 95.2 4.6 2.9e-27 94.9 3.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 dsDNA_bind PF01984.15 KEZ44511.1 - 0.061 13.3 1.7 1 9.3 0.1 2.4 2 1 0 2 2 2 0 Double-stranded DNA-binding domain Spexin PF15171.1 KEZ44511.1 - 0.096 12.6 0.5 0.21 11.6 0.1 1.7 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin CPL PF08144.6 KEZ44512.1 - 9.3e-17 61.2 0.0 3.4e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 CPL (NUC119) domain fn3_3 PF14686.1 KEZ44514.1 - 0.079 13.0 0.0 0.24 11.5 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide lyase family 4, domain II PITH PF06201.8 KEZ44515.1 - 3.7e-37 127.4 0.0 5.8e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KEZ44515.1 - 4.4e-19 68.0 0.0 7.1e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KEZ44515.1 - 0.0003 20.9 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEZ44515.1 - 0.0026 17.8 0.0 0.035 14.2 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 KEZ44515.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE BTB PF00651.26 KEZ44516.1 - 0.0044 16.9 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RecX PF02631.11 KEZ44516.1 - 0.018 15.2 0.2 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 RecX family G-patch PF01585.18 KEZ44517.1 - 0.0024 17.5 0.0 0.0075 16.0 0.0 1.9 1 0 0 1 1 1 1 G-patch domain DUF936 PF06075.7 KEZ44517.1 - 0.23 10.3 34.3 0.3 9.9 23.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Fungal_trans PF04082.13 KEZ44519.1 - 5.2e-09 35.3 0.2 8.6e-09 34.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ44519.1 - 1.2e-05 25.0 7.7 2.6e-05 24.0 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actino_peptide PF14408.1 KEZ44520.1 - 1.9 8.4 4.7 2 8.3 2.4 1.7 1 1 1 2 2 2 0 Ribosomally synthesized peptide in actinomycetes COMPASS-Shg1 PF05205.7 KEZ44521.1 - 0.34 11.2 5.2 0.82 9.9 3.6 1.8 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF342 PF03961.8 KEZ44521.1 - 1.4 7.2 7.1 1.7 6.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PEHE PF15275.1 KEZ44521.1 - 1.8 9.0 7.0 3.4 8.1 4.9 1.5 1 1 0 1 1 1 0 PEHE domain DUF1690 PF07956.6 KEZ44521.1 - 2.1 8.3 8.4 1.1 9.2 3.6 1.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) OmpH PF03938.9 KEZ44521.1 - 2.3 8.1 9.1 2.9 7.7 6.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS6_N PF14661.1 KEZ44521.1 - 5.7 6.2 9.6 26 4.0 6.8 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus COX17 PF05051.8 KEZ44522.1 - 1.9e-19 69.4 6.5 2.4e-19 69.0 4.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DnaJ PF00226.26 KEZ44523.1 - 3e-21 74.9 0.8 4.5e-21 74.3 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 KEZ44523.1 - 0.023 14.7 1.1 0.023 14.7 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Serglycin PF04360.7 KEZ44523.1 - 0.72 9.5 2.9 1.3 8.7 2.0 1.5 1 1 0 1 1 1 0 Serglycin GPI-anchored PF10342.4 KEZ44524.1 - 5.1e-10 39.7 0.0 1.4e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_18 PF00704.23 KEZ44525.1 - 4.4e-88 296.0 1.6 5.5e-88 295.7 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 KEZ44525.1 - 0.034 13.2 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 AP_endonuc_2 PF01261.19 KEZ44525.1 - 0.13 11.5 0.1 4.2 6.5 0.0 2.5 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel LRR_6 PF13516.1 KEZ44527.1 - 7.3e-13 47.1 9.8 0.0022 17.8 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 KEZ44527.1 - 3.2e-09 36.1 9.2 0.00066 19.2 0.0 5.3 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEZ44527.1 - 7.8e-06 25.2 8.6 3.9 7.8 0.2 6.2 6 2 1 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 KEZ44527.1 - 0.0011 18.7 7.1 79 4.1 0.0 6.5 6 0 0 6 6 6 0 Leucine rich repeat UBN2 PF14223.1 KEZ44527.1 - 0.0085 15.8 2.9 0.046 13.5 0.4 3.0 2 1 0 2 2 2 1 gag-polypeptide of LTR copia-type Voldacs PF03517.8 KEZ44527.1 - 0.01 15.6 0.1 0.032 14.0 0.1 1.8 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling UBN2_2 PF14227.1 KEZ44527.1 - 0.023 14.2 4.0 0.044 13.3 0.2 3.1 3 1 0 3 3 3 0 gag-polypeptide of LTR copia-type LRR_8 PF13855.1 KEZ44527.1 - 0.035 13.8 11.9 1.2 8.9 0.3 4.3 3 2 0 3 3 3 0 Leucine rich repeat zf-H2C2_2 PF13465.1 KEZ44528.1 - 1.5e-07 31.3 9.9 3.6e-06 26.9 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ44528.1 - 0.00019 21.5 0.3 0.00019 21.5 0.2 3.8 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ44528.1 - 0.00062 19.9 0.3 0.00062 19.9 0.2 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ44528.1 - 0.54 10.4 4.6 4.3 7.5 0.3 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SUZ PF12752.2 KEZ44530.1 - 4.5e-05 23.8 5.5 4.5e-05 23.8 3.8 3.4 3 2 0 3 3 3 1 SUZ domain DUF4407 PF14362.1 KEZ44530.1 - 0.39 9.6 2.9 0.54 9.1 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP_sub_h PF10775.4 KEZ44532.1 - 3.5e-23 81.0 0.2 5.1e-23 80.5 0.1 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KEZ44532.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Pkinase PF00069.20 KEZ44533.1 - 1e-71 241.1 0.0 1.4e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44533.1 - 7.5e-31 107.1 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KEZ44533.1 - 3.1e-14 53.2 0.3 3.1e-14 53.2 0.2 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KEZ44533.1 - 3e-10 39.5 0.0 5.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 KEZ44533.1 - 4.6e-05 23.1 0.0 0.00021 21.1 0.0 2.1 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 KEZ44533.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3534 PF12053.3 KEZ44533.1 - 0.027 14.3 0.1 0.082 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) YrbL-PhoP_reg PF10707.4 KEZ44533.1 - 0.041 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 KEZ44533.1 - 0.096 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SWI-SNF_Ssr4 PF08549.5 KEZ44534.1 - 3.7e-204 679.8 10.9 4.6e-204 679.5 7.6 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) TPT PF03151.11 KEZ44535.1 - 9.2e-33 113.0 12.1 9.2e-33 113.0 8.4 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEZ44535.1 - 5.1e-06 25.6 13.3 7.7e-06 25.0 9.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEZ44535.1 - 0.00021 21.3 25.0 0.0015 18.5 1.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family NfI_DNAbd_pre-N PF10524.4 KEZ44535.1 - 0.047 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus DUF2681 PF10883.3 KEZ44535.1 - 0.17 12.1 1.1 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Zn_clus PF00172.13 KEZ44537.1 - 0.063 13.1 6.4 0.12 12.2 4.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1509 PF07420.6 KEZ44538.1 - 0.098 11.9 6.7 0.13 11.4 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PRA1 PF03208.14 KEZ44539.1 - 1.6e-35 121.6 2.7 2.6e-35 121.0 1.9 1.2 1 0 0 1 1 1 1 PRA1 family protein RXT2_N PF08595.6 KEZ44539.1 - 0.17 11.7 3.8 0.55 10.0 0.1 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal APC_CDC26 PF10471.4 KEZ44539.1 - 0.29 11.9 0.1 0.29 11.9 0.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Rhodanese PF00581.15 KEZ44540.1 - 6.5e-12 45.8 0.0 1.5e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain SMP PF04927.7 KEZ44540.1 - 0.57 10.1 2.3 1.2 9.1 1.6 1.4 1 0 0 1 1 1 0 Seed maturation protein DNA_pol_phi PF04931.8 KEZ44541.1 - 1.2e-24 86.1 15.8 5.1e-23 80.8 9.4 2.4 2 0 0 2 2 2 2 DNA polymerase phi Proteasome PF00227.21 KEZ44542.1 - 2.8e-47 160.4 0.1 3.7e-32 111.1 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KEZ44542.1 - 1.2e-11 43.7 0.9 1.4e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DnaJ PF00226.26 KEZ44543.1 - 2.9e-12 46.1 2.1 7.3e-12 44.8 1.4 1.8 1 1 0 1 1 1 1 DnaJ domain CwfJ_C_2 PF04676.9 KEZ44544.1 - 4.1e-25 88.1 0.5 8.3e-25 87.1 0.3 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 KEZ44544.1 - 2.5e-24 85.2 0.0 1.1e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 tRNA_int_endo PF01974.12 KEZ44544.1 - 0.14 11.9 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 tRNA intron endonuclease, catalytic C-terminal domain DRIM PF07539.7 KEZ44545.1 - 1.8e-39 134.3 0.5 8.3e-38 128.9 0.0 3.9 3 0 0 3 3 3 1 Down-regulated in metastasis Utp13 PF08625.6 KEZ44545.1 - 0.033 13.8 0.0 0.14 11.7 0.0 2.1 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Cullin PF00888.17 KEZ44546.1 - 6.8e-116 388.1 0.0 1e-115 387.5 0.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEZ44546.1 - 1.7e-26 91.8 1.2 3.8e-26 90.6 0.8 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain MPC PF03650.8 KEZ44547.1 - 6.6e-34 116.4 0.1 7.7e-34 116.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DND1_DSRM PF14709.1 KEZ44547.1 - 0.079 13.2 0.1 0.89 9.8 0.1 2.1 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 CPSase_L_D2 PF02786.12 KEZ44548.1 - 5.6e-80 267.5 0.2 8.8e-80 266.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KEZ44548.1 - 6.6e-66 221.4 0.0 1.1e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KEZ44548.1 - 2.9e-35 120.6 0.1 6.8e-35 119.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEZ44548.1 - 1.4e-31 108.6 0.0 4.5e-31 107.0 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KEZ44548.1 - 5.7e-26 91.6 0.0 1.3e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 KEZ44548.1 - 1.1e-18 66.5 1.4 1.1e-18 66.5 1.0 2.4 3 0 0 3 3 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KEZ44548.1 - 3.5e-18 65.9 0.1 7.7e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEZ44548.1 - 3.9e-15 55.4 0.0 4.5e-14 51.9 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KEZ44548.1 - 1.3e-10 41.0 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 KEZ44548.1 - 6.7e-10 38.4 0.7 6.1e-07 28.9 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 KEZ44548.1 - 7.3e-07 28.7 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEZ44548.1 - 1.2e-05 24.9 0.0 3.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KEZ44548.1 - 8.1e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 KEZ44548.1 - 0.00014 21.1 0.0 0.033 13.3 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 KEZ44548.1 - 0.00046 20.4 0.0 0.018 15.3 0.1 3.0 2 1 1 3 3 2 1 HlyD family secretion protein HlyD PF00529.15 KEZ44548.1 - 0.0017 17.6 1.8 0.0049 16.2 0.0 2.5 3 0 0 3 3 3 1 HlyD family secretion protein DUF2118 PF09891.4 KEZ44548.1 - 0.013 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GARS_A PF01071.14 KEZ44548.1 - 0.017 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.6 KEZ44548.1 - 0.05 12.7 0.1 0.094 11.8 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PYNP_C PF07831.8 KEZ44548.1 - 0.055 12.9 1.6 1.3 8.4 0.0 3.1 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain GCV_H PF01597.14 KEZ44548.1 - 0.16 11.6 0.2 0.66 9.6 0.1 2.0 1 0 0 1 1 1 0 Glycine cleavage H-protein Cyclin_N PF00134.18 KEZ44549.1 - 1.4e-09 37.5 0.1 2.7e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 KEZ44549.1 - 0.098 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat ABC_tran PF00005.22 KEZ44550.1 - 1.7e-36 125.5 0.0 6.1e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ44550.1 - 1.9e-28 99.6 33.1 4.4e-22 78.8 12.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KEZ44550.1 - 2.5e-08 34.2 0.0 1.2 9.0 0.0 4.2 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KEZ44550.1 - 2.8e-07 29.9 0.3 0.81 8.8 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEZ44550.1 - 2.3e-05 23.8 0.1 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KEZ44550.1 - 0.00033 19.6 0.0 0.051 12.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 KEZ44550.1 - 0.00053 19.4 0.2 0.63 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 KEZ44550.1 - 0.0011 18.5 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 KEZ44550.1 - 0.0018 18.1 0.0 0.21 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KEZ44550.1 - 0.0026 17.6 0.3 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KEZ44550.1 - 0.005 16.7 0.0 2.1 8.3 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KEZ44550.1 - 0.0067 17.2 0.2 4.8 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KEZ44550.1 - 0.0067 16.1 0.2 2.4 7.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KEZ44550.1 - 0.011 14.8 0.0 4.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ44550.1 - 0.033 14.3 0.1 16 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 KEZ44550.1 - 0.039 14.2 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KEZ44550.1 - 0.04 14.4 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KEZ44550.1 - 0.09 12.1 0.2 22 4.3 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain DUF87 PF01935.12 KEZ44550.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_18 PF13238.1 KEZ44550.1 - 0.18 12.1 0.1 45 4.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2427 PF10348.4 KEZ44551.1 - 1.8e-09 37.0 0.5 1.8e-09 37.0 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.12 KEZ44551.1 - 2.4e-07 30.7 1.4 4.8e-07 29.7 1.0 1.4 1 0 0 1 1 1 1 DOMON domain AWPM-19 PF05512.6 KEZ44551.1 - 0.047 13.6 3.1 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 AWPM-19-like family UPF0121 PF03661.8 KEZ44551.1 - 0.14 11.3 0.1 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) DUF2231 PF09990.4 KEZ44551.1 - 0.26 11.6 9.6 0.073 13.4 3.4 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) LSM PF01423.17 KEZ44552.1 - 6.1e-16 57.7 0.0 8.9e-16 57.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 KEZ44553.1 - 2.4e-22 78.4 0.0 3.4e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KEZ44553.1 - 2.6e-21 75.1 0.2 5.9e-21 74.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 ATP-synt_ab PF00006.20 KEZ44554.1 - 2.5e-70 236.3 0.0 3.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEZ44554.1 - 2.4e-26 92.4 0.1 8.6e-26 90.6 0.1 2.0 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEZ44554.1 - 2e-15 56.7 4.0 3.3e-15 56.0 2.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KEZ44554.1 - 0.0026 17.6 0.8 0.0078 16.0 0.6 1.9 1 0 0 1 1 1 1 HAS barrel domain Carb_kinase PF01256.12 KEZ44555.1 - 7.6e-53 179.2 0.1 1e-52 178.8 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KEZ44555.1 - 2.5e-05 23.6 0.0 5.7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KEZ44555.1 - 0.021 13.9 0.0 0.085 11.9 0.0 1.9 2 0 0 2 2 2 0 pfkB family carbohydrate kinase CorA PF01544.13 KEZ44556.1 - 7.6e-37 126.9 0.3 8.3e-36 123.5 0.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CBF PF03914.12 KEZ44557.1 - 5.9e-47 159.1 0.3 1.6e-46 157.7 0.0 1.9 2 0 0 2 2 2 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.9 KEZ44558.1 - 2.3e-53 179.9 5.5 2.9e-53 179.6 3.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) BON PF04972.12 KEZ44558.1 - 0.034 13.8 0.5 1.8 8.3 0.0 3.0 3 0 0 3 3 3 0 BON domain Orthopox_A5L PF06193.6 KEZ44558.1 - 0.034 14.0 1.4 0.048 13.5 0.6 1.7 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like DivIC PF04977.10 KEZ44558.1 - 7.6 6.0 8.5 0.31 10.5 0.9 2.5 3 1 0 3 3 3 0 Septum formation initiator MSC PF09402.5 KEZ44559.1 - 2.9e-101 338.5 0.0 4.4e-101 337.9 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KEZ44559.1 - 2.1e-17 62.3 0.1 4.2e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 KEZ44559.1 - 0.005 16.3 0.1 0.0095 15.4 0.1 1.5 1 0 0 1 1 1 1 Thymopoietin protein DUF3637 PF12337.3 KEZ44559.1 - 0.064 13.2 0.1 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) FAD_binding_3 PF01494.14 KEZ44560.1 - 2.5e-20 72.8 0.0 7.9e-18 64.6 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ44560.1 - 3.6e-05 22.8 0.1 0.061 12.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ44560.1 - 0.00055 18.9 0.3 0.0023 16.8 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ44560.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KEZ44560.1 - 0.0037 16.1 0.0 0.0067 15.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 KEZ44560.1 - 0.016 15.2 0.1 0.068 13.2 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ44560.1 - 0.029 13.3 0.0 0.095 11.5 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ44560.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 KEZ44560.1 - 0.1 11.6 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 KEZ44560.1 - 0.18 10.2 0.1 0.25 9.7 0.1 1.4 1 1 0 1 1 1 0 HI0933-like protein Complex1_49kDa PF00346.14 KEZ44561.1 - 1.5e-133 443.9 0.0 2e-133 443.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 KEZ44562.1 - 7.8e-27 93.6 0.0 1.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEZ44562.1 - 1.3e-14 53.0 0.0 1.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 KEZ44563.1 - 1.6e-37 128.3 1.4 3e-37 127.4 0.4 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KEZ44563.1 - 4.7e-28 96.7 0.0 9.3e-28 95.8 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KEZ44563.1 - 1e-25 89.0 1.0 2.4e-25 87.8 0.3 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KEZ44563.1 - 8.1e-16 57.1 1.8 8.1e-16 57.1 1.2 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KEZ44563.1 - 3.1e-05 23.9 0.0 0.00027 20.9 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 KEZ44563.1 - 0.00051 20.1 0.0 0.00089 19.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KEZ44563.1 - 0.02 15.1 0.1 0.049 13.9 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding MoeZ_MoeB PF05237.8 KEZ44563.1 - 0.046 13.3 0.3 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 MoeZ/MoeB domain TrkA_N PF02254.13 KEZ44563.1 - 0.099 12.6 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Telomere_reg-2 PF10193.4 KEZ44564.1 - 2.8e-39 133.8 0.0 5.7e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein NESP55 PF06390.7 KEZ44564.1 - 0.064 12.6 3.0 0.12 11.7 2.1 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pkinase PF00069.20 KEZ44565.1 - 4e-55 186.7 0.0 5.6e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44565.1 - 1.2e-40 139.1 0.0 1.9e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ44565.1 - 3.2e-06 26.3 0.0 7.8e-06 25.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEZ44565.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEZ44565.1 - 0.087 12.5 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNase PF00565.12 KEZ44567.1 - 8.1e-24 83.9 0.0 1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TFIIF_beta PF02270.10 KEZ44568.1 - 1.5e-61 208.5 0.4 1.9e-61 208.2 0.3 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Band_7 PF01145.20 KEZ44569.1 - 2.2e-23 83.0 2.0 5e-23 81.9 1.4 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.18 KEZ44569.1 - 1.8e-18 65.7 0.1 3.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEZ44569.1 - 9.3e-08 31.6 0.0 2.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like APH PF01636.18 KEZ44569.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ubiquitin_2 PF14560.1 KEZ44569.1 - 0.015 15.4 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_11 PF13086.1 KEZ44569.1 - 0.022 14.3 1.0 0.036 13.6 0.7 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KEZ44570.1 - 4.7e-67 219.6 25.3 1.5e-08 34.1 0.2 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 KEZ44570.1 - 1.4e-21 76.4 0.3 2.5e-21 75.6 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family LSM PF01423.17 KEZ44570.1 - 8e-11 41.3 1.1 8e-11 41.3 0.8 2.6 3 0 0 3 3 3 1 LSM domain eIF2A PF08662.6 KEZ44570.1 - 8.2e-05 22.3 0.0 0.0073 16.0 0.0 3.6 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KEZ44570.1 - 0.00055 18.1 9.1 0.046 11.8 0.1 4.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 KEZ44570.1 - 0.012 13.8 0.1 0.21 9.7 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) CorA PF01544.13 KEZ44571.1 - 7.7e-06 25.1 0.0 1.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.20 KEZ44572.1 - 4.1e-56 190.0 0.0 1.1e-54 185.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44572.1 - 2.4e-26 92.3 0.1 2.1e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KEZ44572.1 - 4.7e-05 23.2 2.3 0.0065 16.2 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KEZ44572.1 - 9.7e-05 21.4 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KEZ44572.1 - 0.00045 19.3 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KEZ44572.1 - 0.041 12.6 0.1 0.063 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KEZ44572.1 - 0.048 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KEZ44572.1 - 0.15 11.4 1.1 0.4 10.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.3 KEZ44573.1 - 2.8e-124 414.6 4.6 3.7e-124 414.1 3.2 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nefa_Nip30_N PF10187.4 KEZ44574.1 - 2e-24 85.7 15.5 2e-24 85.7 10.7 2.4 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 CRC_subunit PF08624.5 KEZ44575.1 - 2.6e-57 192.6 0.0 3.6e-57 192.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Trypan_PARP PF05887.6 KEZ44575.1 - 0.28 11.0 24.7 0.83 9.4 17.1 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Autophagy_act_C PF03987.10 KEZ44576.1 - 4.3e-11 42.8 0.1 8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 KEZ44577.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ44577.1 - 0.042 13.4 0.0 0.17 11.5 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KEZ44578.1 - 3.2e-20 71.1 17.5 3.1e-08 33.1 0.0 6.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 KEZ44578.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Ribonuc_L-PSP PF01042.16 KEZ44579.1 - 5.4e-39 132.6 0.0 6e-39 132.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.13 KEZ44580.1 - 1.7e-80 269.8 17.1 1.7e-80 269.8 11.9 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KEZ44580.1 - 1.1e-19 70.7 1.1 1.3e-18 67.1 0.3 2.1 1 1 1 2 2 2 2 MIR domain CAP59_mtransfer PF11735.3 KEZ44581.1 - 2.5e-72 243.0 0.0 4.2e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CoA_transf_3 PF02515.12 KEZ44582.1 - 7.5e-61 204.7 0.0 1.5e-60 203.7 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III Cytochrom_CIII PF02085.11 KEZ44582.1 - 0.02 14.9 4.6 0.042 13.9 3.2 1.5 1 0 0 1 1 1 0 Class III cytochrome C family PHD PF00628.24 KEZ44582.1 - 0.065 12.9 9.0 0.12 12.1 6.2 1.4 1 0 0 1 1 1 0 PHD-finger DUF2318 PF10080.4 KEZ44582.1 - 0.16 11.7 0.6 0.36 10.6 0.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF4355 PF14265.1 KEZ44582.1 - 0.87 9.5 4.9 11 6.0 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) YyzF PF14116.1 KEZ44582.1 - 9 6.3 6.4 9.3 6.2 0.1 3.0 3 0 0 3 3 3 0 YyzF-like protein Glyco_hydro_20 PF00728.17 KEZ44583.1 - 2.2e-91 306.6 0.0 2.7e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KEZ44583.1 - 7.8e-23 81.5 0.0 1.5e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KEZ44583.1 - 2.1e-06 28.2 0.0 0.0026 18.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 KEZ44584.1 - 3.7e-60 203.7 0.0 7.1e-60 202.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 KEZ44585.1 - 3.7e-18 65.6 0.0 6.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KEZ44585.1 - 1.8e-06 26.8 0.0 5.4e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HET PF06985.6 KEZ44586.1 - 5.1e-05 23.4 0.2 0.00027 21.0 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_16 PF00722.16 KEZ44587.1 - 1.5e-44 151.5 1.3 2.2e-44 150.9 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topoisom_I_N PF02919.10 KEZ44588.1 - 2e-95 318.1 6.6 2e-95 318.1 4.6 3.3 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KEZ44588.1 - 9e-89 296.6 6.7 3.2e-88 294.7 4.6 2.0 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KEZ44588.1 - 3.2e-29 100.4 0.2 3.2e-29 100.4 0.1 2.7 3 0 0 3 3 3 1 C-terminal topoisomerase domain DWNN PF08783.6 KEZ44588.1 - 0.042 13.7 0.3 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 DWNN domain RolB_RolC PF02027.12 KEZ44588.1 - 0.11 11.6 0.1 0.29 10.2 0.1 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family ATP-synt PF00231.14 KEZ44589.1 - 3.7e-71 239.8 1.3 4.2e-71 239.6 0.9 1.0 1 0 0 1 1 1 1 ATP synthase Amino_oxidase PF01593.19 KEZ44590.1 - 1.2e-83 281.6 0.0 1.8e-83 281.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 KEZ44590.1 - 2.4e-08 33.9 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.14 KEZ44590.1 - 4.4e-07 30.0 4.0 5.3e-07 29.8 1.3 2.3 2 1 0 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.1 KEZ44590.1 - 6.5e-06 26.0 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.5 KEZ44590.1 - 6.9e-06 26.3 1.5 1.5e-05 25.2 1.1 1.6 1 0 0 1 1 1 1 HMG-box domain DAO PF01266.19 KEZ44590.1 - 0.025 13.5 0.1 0.26 10.1 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ44590.1 - 0.027 14.5 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ44590.1 - 0.034 13.0 0.0 7 5.4 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DUF2057 PF09829.4 KEZ44590.1 - 0.083 12.5 0.0 0.26 10.9 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) FAD_binding_2 PF00890.19 KEZ44590.1 - 0.69 8.6 8.3 1.8 7.3 1.5 3.5 3 1 0 3 3 3 0 FAD binding domain Sec1 PF00995.18 KEZ44591.1 - 8e-130 434.1 0.0 9.1e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.1 KEZ44592.1 - 2.8e-40 138.3 0.0 6.8e-34 117.3 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KEZ44592.1 - 1.2e-18 67.2 0.0 1.8e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEZ44592.1 - 6.4e-12 45.2 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KEZ44592.1 - 0.00015 20.7 0.4 0.0061 15.3 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Pkinase PF00069.20 KEZ44594.1 - 1.4e-71 240.7 0.0 1.8e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44594.1 - 3.7e-33 114.6 0.0 5.6e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ44594.1 - 0.00048 19.1 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KEZ44594.1 - 0.0023 17.3 0.0 0.008 15.5 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KEZ44594.1 - 0.021 13.9 0.0 0.057 12.4 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 KEZ44595.1 - 1.5e-26 92.5 0.0 1.7e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ44595.1 - 1.9e-07 30.8 0.0 7.5e-07 28.9 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 KEZ44595.1 - 4e-05 23.4 0.1 4.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KEZ44595.1 - 0.0014 18.3 0.1 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 UEV domain MFS_1 PF07690.11 KEZ44596.1 - 7.5e-40 136.7 24.0 9.7e-40 136.3 16.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ44596.1 - 5.3e-13 48.3 7.7 5.3e-13 48.3 5.3 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KEZ44596.1 - 3.8e-10 38.5 2.8 3.8e-10 38.5 1.9 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KEZ44596.1 - 0.33 8.9 8.8 1.5 6.8 0.0 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ABC_membrane PF00664.18 KEZ44597.1 - 1.4e-71 241.1 33.0 3.7e-38 131.5 9.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ44597.1 - 3e-64 215.4 0.0 2.5e-32 112.0 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ44597.1 - 5.5e-16 58.4 2.5 2.4e-08 33.4 0.1 3.6 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ44597.1 - 8.6e-13 48.8 0.1 0.0054 16.7 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ44597.1 - 1e-10 41.8 0.7 4.3e-06 26.8 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain ABC_ATPase PF09818.4 KEZ44597.1 - 3.7e-10 38.9 0.1 0.002 16.8 0.0 3.6 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KEZ44597.1 - 1.8e-07 30.6 0.6 0.0006 19.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEZ44597.1 - 2.8e-07 29.8 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ44597.1 - 3.3e-07 31.1 0.1 0.0038 18.0 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEZ44597.1 - 9.2e-07 29.0 1.0 0.13 12.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KEZ44597.1 - 8.5e-06 25.0 0.4 0.031 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KEZ44597.1 - 5.6e-05 22.6 0.3 0.41 10.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KEZ44597.1 - 8.5e-05 22.9 6.4 0.02 15.1 1.4 2.7 2 1 1 3 3 2 2 AAA domain AAA_30 PF13604.1 KEZ44597.1 - 0.0001 21.9 6.5 0.27 10.8 0.1 4.2 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.1 KEZ44597.1 - 0.00017 21.8 0.3 0.16 12.2 0.2 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KEZ44597.1 - 0.0002 20.9 0.0 0.25 10.8 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 KEZ44597.1 - 0.00021 21.1 2.1 0.15 12.0 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.1 KEZ44597.1 - 0.00026 19.6 4.6 0.00029 19.5 1.4 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) AAA_19 PF13245.1 KEZ44597.1 - 0.0003 20.4 0.1 0.077 12.7 0.0 3.2 3 0 0 3 3 2 1 Part of AAA domain AAA PF00004.24 KEZ44597.1 - 0.00045 20.4 2.9 17 5.5 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ44597.1 - 0.00061 19.5 0.3 2.4 7.8 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KEZ44597.1 - 0.0012 18.6 0.6 3.9 7.3 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEZ44597.1 - 0.0043 16.9 0.0 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 KEZ44597.1 - 0.0043 16.6 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 KEZ44597.1 - 0.0049 16.5 0.2 0.31 10.7 0.2 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KEZ44597.1 - 0.0052 16.2 2.4 0.13 11.7 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 KEZ44597.1 - 0.0063 15.6 0.0 0.92 8.5 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin SRP54 PF00448.17 KEZ44597.1 - 0.0067 15.8 0.0 17 4.7 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 KEZ44597.1 - 0.019 14.9 0.1 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 KEZ44597.1 - 0.033 13.3 0.0 6.9 5.7 0.0 2.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 KEZ44597.1 - 0.12 12.5 0.0 28 4.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF3094 PF11293.3 KEZ44597.1 - 0.31 10.5 2.8 1.4 8.4 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) BLVR PF06375.6 KEZ44597.1 - 1.7 8.4 16.0 0.017 14.9 5.6 1.6 2 0 0 2 2 1 0 Bovine leukaemia virus receptor (BLVR) DUF2868 PF11067.3 KEZ44597.1 - 7.5 5.5 7.9 22 4.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2868) Abhydrolase_6 PF12697.2 KEZ44598.1 - 8.1e-20 71.6 8.8 1.8e-19 70.5 6.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ44598.1 - 8.6e-14 51.5 0.1 2.7e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEZ44598.1 - 1.8e-08 34.1 0.0 4.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEZ44598.1 - 2e-07 30.8 0.6 3.8e-07 29.9 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KEZ44598.1 - 0.00023 20.8 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 KEZ44598.1 - 0.0064 15.9 0.8 0.011 15.1 0.6 1.5 1 1 0 1 1 1 1 Putative esterase DLH PF01738.13 KEZ44598.1 - 0.017 14.4 0.0 0.078 12.2 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2048 PF09752.4 KEZ44598.1 - 0.042 12.7 0.1 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) FYVE PF01363.16 KEZ44599.1 - 5.4e-09 35.8 2.2 5.4e-09 35.8 1.5 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 KEZ44599.1 - 5.1e-08 32.6 6.0 5.1e-08 32.6 4.2 3.7 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 KEZ44599.1 - 0.00015 21.8 9.4 0.011 15.7 2.7 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEZ44599.1 - 0.35 10.9 18.5 0.028 14.4 4.0 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ44599.1 - 2.1 8.0 14.5 0.023 14.3 2.2 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 KEZ44599.1 - 2.2 7.8 8.0 0.1 12.0 0.4 2.4 3 0 0 3 3 3 0 Rad50 zinc hook motif CarbpepA_inh PF02977.10 KEZ44599.1 - 2.9 7.5 5.7 29 4.3 0.1 3.3 2 1 0 2 2 2 0 Carboxypeptidase A inhibitor zf-C3HC4_3 PF13920.1 KEZ44599.1 - 4.3 7.0 13.4 29 4.4 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) C2 PF00168.25 KEZ44600.1 - 1.4e-73 242.7 3.8 4.5e-25 87.3 0.0 5.6 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 KEZ44600.1 - 0.038 14.1 0.5 0.21 11.7 0.0 2.5 3 0 0 3 3 3 0 Putative integral membrane protein conserved region (DUF2404) Proteasome PF00227.21 KEZ44601.1 - 5.5e-48 162.7 0.3 6.6e-48 162.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 KEZ44601.1 - 0.0021 17.2 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF554) Glycos_transf_3 PF00591.16 KEZ44602.1 - 5.5e-62 209.4 0.0 8e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KEZ44602.1 - 1e-09 37.8 0.1 9.6e-09 34.7 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain Lip_A_acyltrans PF03279.8 KEZ44602.1 - 0.084 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Methyltransf_18 PF12847.2 KEZ44603.1 - 0.00019 21.9 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ44603.1 - 0.0017 18.0 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44603.1 - 0.0063 15.6 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ44603.1 - 0.07 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 KEZ44603.1 - 0.09 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 KEZ44604.1 - 8.9e-20 70.0 0.2 1e-19 69.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KEZ44604.1 - 0.00032 20.5 0.2 0.00036 20.3 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 KEZ44604.1 - 0.032 14.0 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain SpoA PF01052.15 KEZ44604.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Rad60-SLD PF11976.3 KEZ44605.1 - 1.3e-14 53.6 0.2 2.6e-14 52.6 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KEZ44605.1 - 5.9e-05 22.3 0.1 0.00015 21.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family PSD5 PF07637.6 KEZ44605.1 - 7.6 6.6 7.3 1.3 9.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) IncA PF04156.9 KEZ44606.1 - 0.0028 17.2 3.4 0.0028 17.2 2.3 7.1 1 1 5 6 6 6 3 IncA protein Filament PF00038.16 KEZ44606.1 - 0.0037 16.7 11.0 0.0037 16.7 7.6 7.0 3 2 2 7 7 7 3 Intermediate filament protein Reo_sigmaC PF04582.7 KEZ44606.1 - 0.02 14.0 32.4 0.2 10.7 2.8 5.4 4 1 0 5 5 5 0 Reovirus sigma C capsid protein DivIC PF04977.10 KEZ44606.1 - 5.2 6.6 0.0 5.2 6.6 0.0 10.6 7 4 5 12 12 12 0 Septum formation initiator Ammonium_transp PF00909.16 KEZ44607.1 - 2e-119 398.6 28.8 2.3e-119 398.4 19.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Sec10 PF07393.6 KEZ44608.1 - 1.6e-221 737.3 9.1 2e-221 737.0 6.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Glyco_hydro_18 PF00704.23 KEZ44610.1 - 2.2e-70 237.8 0.5 3.4e-70 237.2 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KEZ44610.1 - 3.3e-08 33.3 5.8 3.3e-08 33.3 4.0 4.1 3 1 0 3 3 3 1 Chitin recognition protein LysM PF01476.15 KEZ44611.1 - 3e-20 71.8 0.0 6.1e-06 26.0 0.0 6.5 6 0 0 6 6 6 5 LysM domain Met_10 PF02475.11 KEZ44613.1 - 3.6e-72 242.1 0.0 5.4e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Prenyltransf PF01255.14 KEZ44613.1 - 1.2e-05 24.6 0.0 2.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Methyltransf_26 PF13659.1 KEZ44613.1 - 0.034 14.1 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MethyltransfD12 PF02086.10 KEZ44613.1 - 0.094 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF1752 PF08550.5 KEZ44614.1 - 1.6e-08 33.9 5.7 3.3e-08 32.9 3.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RNB PF00773.14 KEZ44615.1 - 1.1e-48 166.2 0.0 2.1e-48 165.3 0.0 1.5 1 0 0 1 1 1 1 RNB domain Trypan_PARP PF05887.6 KEZ44616.1 - 0.099 12.4 20.5 0.034 13.9 8.2 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 KEZ44616.1 - 4.1 6.4 23.1 6.3 5.8 16.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein WD40 PF00400.27 KEZ44617.1 - 1.2e-10 40.8 0.3 3.2e-09 36.3 0.2 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 KEZ44617.1 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Chitin_synth_2 PF03142.10 KEZ44618.1 - 7.9e-294 974.9 0.1 1e-293 974.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KEZ44618.1 - 7.4e-20 71.4 0.3 1.9e-19 70.1 0.2 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ44618.1 - 3.9e-16 59.5 0.0 9.8e-15 54.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KEZ44618.1 - 2.7e-13 49.5 0.0 1.5e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KEZ44618.1 - 2.4e-05 23.7 0.0 0.00054 19.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEZ44618.1 - 0.0056 16.3 0.0 0.074 12.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1418 PF07214.7 KEZ44618.1 - 4.8 6.8 7.2 18 5.0 4.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Sel1 PF08238.7 KEZ44619.1 - 2.3e-34 117.0 31.3 5.2e-05 23.7 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat Pkinase PF00069.20 KEZ44620.1 - 7.8e-68 228.4 0.0 1.2e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44620.1 - 1.6e-41 142.0 0.0 2.4e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ44620.1 - 1.5e-07 30.7 0.1 3.3e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 KEZ44620.1 - 1.3e-06 28.2 1.8 0.00025 20.9 0.0 3.3 4 0 0 4 4 4 2 POLO box duplicated region Kdo PF06293.9 KEZ44620.1 - 0.006 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 KEZ44621.1 - 1e-37 128.8 0.8 8.3e-37 125.9 0.6 2.1 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SBDS PF01172.13 KEZ44621.1 - 2.5e-20 72.0 0.1 5.2e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.15 KEZ44623.1 - 1.3e-25 90.3 0.1 1.8e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.15 KEZ44624.1 - 2e-62 210.2 5.7 8.6e-62 208.1 4.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ44624.1 - 6.7e-46 156.1 4.2 6.7e-46 156.1 2.9 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ44624.1 - 1e-30 107.8 0.0 1e-29 104.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ44624.1 - 4.2e-23 81.1 0.0 8.4e-23 80.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEZ44624.1 - 2.9e-19 68.2 0.0 7.5e-19 66.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEZ44624.1 - 6.2e-15 55.8 0.1 2.5e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ44624.1 - 5.8e-07 29.3 1.2 1.4e-05 24.8 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEZ44624.1 - 0.086 13.0 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 KEZ44625.1 - 1.8e-39 135.0 0.0 2.1e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 KEZ44626.1 - 1.1e-21 76.5 0.3 4.2e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 KEZ44626.1 - 0.053 13.5 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 UBX domain Ribosomal_L36e PF01158.13 KEZ44627.1 - 5.5e-40 135.3 5.1 6.2e-40 135.1 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 KEZ44627.1 - 0.014 14.5 0.1 0.016 14.3 0.1 1.1 1 0 0 1 1 1 0 LemA family PRA-PH PF01503.12 KEZ44627.1 - 0.1 12.9 0.0 1.5 9.1 0.0 2.0 1 1 1 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase 14-3-3 PF00244.15 KEZ44629.1 - 3.1e-114 379.9 3.8 3.7e-114 379.6 2.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KEZ44629.1 - 0.012 15.5 0.2 5.7 6.9 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF327 PF03885.8 KEZ44629.1 - 0.17 11.7 1.4 1.6 8.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF327) HisKA PF00512.20 KEZ44629.1 - 0.51 10.3 2.0 9.3 6.3 0.0 3.2 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain Syja_N PF02383.13 KEZ44630.1 - 2.8e-82 276.0 0.0 4.7e-82 275.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KEZ44630.1 - 7.7e-23 81.7 0.1 1.3e-22 80.9 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Suf PF05843.9 KEZ44631.1 - 9e-05 22.3 4.1 0.072 12.8 0.0 3.3 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KEZ44631.1 - 0.00075 19.9 5.7 7.9 7.4 0.0 6.8 6 3 3 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ44631.1 - 0.011 16.3 3.9 0.77 10.5 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat Peptidase_S80 PF07230.6 KEZ44631.1 - 0.014 13.7 0.0 0.022 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) peroxidase PF00141.18 KEZ44632.1 - 6.4e-50 169.7 0.0 1e-49 169.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Homeobox PF00046.24 KEZ44633.1 - 8.4e-14 50.9 3.1 2.1e-13 49.6 2.2 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KEZ44633.1 - 0.0021 17.7 0.2 0.0055 16.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain OmpH PF03938.9 KEZ44633.1 - 4.7 7.1 10.4 11 5.9 7.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAD_2 PF13419.1 KEZ44634.1 - 3.4e-13 50.2 0.0 4.2e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ44634.1 - 1.9e-09 37.0 0.0 3.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEZ44634.1 - 2.1e-07 31.5 0.0 2.1e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ44634.1 - 0.0034 17.5 0.0 0.0051 16.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.1 KEZ44634.1 - 0.033 14.2 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 GN3L_Grn1 PF08701.6 KEZ44635.1 - 2.2e-26 91.5 17.8 4.1e-26 90.7 12.3 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KEZ44635.1 - 4.9e-19 68.4 0.0 4.1e-13 49.2 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEZ44635.1 - 3.8e-08 32.9 0.0 0.0046 16.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KEZ44635.1 - 8.2e-06 25.7 0.7 0.13 12.0 0.1 3.6 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KEZ44635.1 - 0.0012 18.0 0.1 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KEZ44635.1 - 0.0015 17.8 0.1 0.091 12.0 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.1 KEZ44635.1 - 0.0051 16.8 3.1 0.029 14.3 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KEZ44635.1 - 0.0097 16.3 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 KEZ44635.1 - 0.015 14.7 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KEZ44635.1 - 0.07 11.8 0.1 0.07 11.8 0.0 2.0 2 0 0 2 2 2 0 ArgK protein RNB PF00773.14 KEZ44636.1 - 9.6e-93 311.0 0.1 1.5e-92 310.3 0.1 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KEZ44636.1 - 4e-11 43.1 0.8 4e-11 43.1 0.5 2.8 3 1 0 3 3 3 1 PIN domain CRC_subunit PF08624.5 KEZ44637.1 - 9.5e-55 184.3 0.0 1.3e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.18 KEZ44638.1 - 3.8e-09 36.4 0.0 6.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEZ44638.1 - 0.00044 20.3 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KEZ44638.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF4407 PF14362.1 KEZ44638.1 - 0.54 9.1 13.8 0.67 8.8 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAM-associated PF14303.1 KEZ44638.1 - 1.4 9.2 35.2 0.05 13.9 15.8 2.4 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Paf1 PF03985.8 KEZ44638.1 - 7.2 5.2 28.0 13 4.4 19.4 1.6 1 0 0 1 1 1 0 Paf1 CRA PF06589.6 KEZ44639.1 - 0.044 13.0 0.7 0.17 11.2 0.0 2.3 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Mid2 PF04478.7 KEZ44639.1 - 0.14 11.5 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Shisa PF13908.1 KEZ44639.1 - 0.61 10.2 0.0 0.61 10.2 0.0 3.4 2 2 2 4 4 4 0 Wnt and FGF inhibitory regulator Gemini_mov PF01708.11 KEZ44639.1 - 1.6 8.3 0.0 1.6 8.3 0.0 2.9 2 0 0 2 2 2 0 Geminivirus putative movement protein G6PD_C PF02781.11 KEZ44640.1 - 8.3e-135 448.3 0.0 1.1e-134 447.8 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KEZ44640.1 - 1.2e-62 211.4 0.0 2e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain AMP-binding PF00501.23 KEZ44641.1 - 1.9e-94 316.4 0.0 2.5e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ44641.1 - 5.2e-09 36.9 0.0 1.5e-08 35.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SLD3 PF08639.5 KEZ44642.1 - 1.3e-105 353.9 0.3 2.7e-105 352.8 0.2 1.6 1 0 0 1 1 1 1 DNA replication regulator SLD3 Trs65 PF12735.2 KEZ44643.1 - 1.9e-69 234.3 0.0 3e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Ctf8 PF09696.5 KEZ44643.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ctf8 DUF11 PF01345.13 KEZ44643.1 - 0.67 10.0 3.4 0.49 10.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF11 FF PF01846.14 KEZ44644.1 - 4.2e-51 170.6 12.3 4.7e-15 55.2 0.0 7.2 6 1 0 6 6 6 6 FF domain WW PF00397.21 KEZ44644.1 - 4.1e-18 64.9 15.2 7.4e-10 38.5 2.5 2.7 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.22 KEZ44645.1 - 7.2e-33 113.7 0.0 9.7e-16 58.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 KEZ44645.1 - 1.1e-13 50.4 6.0 1.1e-13 50.4 4.1 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KEZ44645.1 - 1.7e-11 44.5 8.9 0.11 12.4 0.0 4.8 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 KEZ44645.1 - 5.3e-10 38.9 1.9 0.0017 17.5 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KEZ44645.1 - 5.7e-07 28.9 0.1 1.1 8.1 0.0 4.3 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 KEZ44645.1 - 2.9e-06 28.1 0.2 0.049 14.4 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 KEZ44645.1 - 1.2e-05 25.4 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KEZ44645.1 - 1.6e-05 25.2 0.0 0.16 12.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEZ44645.1 - 7.4e-05 22.9 0.0 0.017 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ44645.1 - 8.8e-05 21.9 0.4 0.093 12.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KEZ44645.1 - 0.00013 21.2 1.8 0.58 9.3 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ44645.1 - 0.00017 21.6 0.1 0.23 11.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Fer4 PF00037.22 KEZ44645.1 - 0.00017 21.0 4.1 0.00017 21.0 2.9 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain RNA_helicase PF00910.17 KEZ44645.1 - 0.00029 20.9 0.0 0.16 12.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase UPF0079 PF02367.12 KEZ44645.1 - 0.00054 19.5 0.1 0.0071 15.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 KEZ44645.1 - 0.00083 19.7 0.1 0.078 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KEZ44645.1 - 0.00085 19.0 0.6 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KEZ44645.1 - 0.001 18.5 1.4 0.077 12.4 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain VirE PF05272.6 KEZ44645.1 - 0.0013 18.2 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_21 PF14697.1 KEZ44645.1 - 0.0013 18.5 11.4 0.0025 17.6 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.7 KEZ44645.1 - 0.0014 18.2 1.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KEZ44645.1 - 0.0016 18.3 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEZ44645.1 - 0.0037 16.6 0.1 2 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 KEZ44645.1 - 0.0046 17.2 8.1 0.0048 17.2 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_5 PF07728.9 KEZ44645.1 - 0.0048 16.6 0.5 0.18 11.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 KEZ44645.1 - 0.0073 15.7 0.2 3.1 7.1 0.0 2.8 3 0 0 3 3 3 1 Thymidylate kinase AAA_13 PF13166.1 KEZ44645.1 - 0.011 14.2 0.0 0.011 14.2 0.0 1.9 3 0 0 3 3 2 0 AAA domain Fer4_6 PF12837.2 KEZ44645.1 - 0.015 15.1 2.7 0.015 15.1 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Rad17 PF03215.10 KEZ44645.1 - 0.017 13.8 0.0 0.19 10.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Miro PF08477.8 KEZ44645.1 - 0.02 15.3 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Fer4_9 PF13187.1 KEZ44645.1 - 0.025 14.8 1.9 0.025 14.8 1.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_28 PF13521.1 KEZ44645.1 - 0.029 14.3 0.2 2 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KEZ44645.1 - 0.033 13.0 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Fer4_16 PF13484.1 KEZ44645.1 - 0.035 14.8 0.1 0.035 14.8 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_14 PF13173.1 KEZ44645.1 - 0.073 12.9 0.4 14 5.5 0.0 3.0 2 2 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KEZ44645.1 - 0.095 11.6 0.0 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.4 KEZ44645.1 - 0.12 11.8 1.7 0.32 10.4 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 KEZ44645.1 - 0.14 12.1 0.0 12 5.8 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KEZ44645.1 - 0.14 11.7 0.2 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KEZ44645.1 - 0.23 11.0 0.9 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KEZ44645.1 - 0.25 11.0 1.5 11 5.6 0.0 2.4 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 KEZ44645.1 - 0.25 10.2 0.6 3.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein Fer4_8 PF13183.1 KEZ44645.1 - 0.58 10.2 9.5 0.34 10.9 1.2 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 KEZ44645.1 - 3.1 7.6 16.8 0.15 11.8 1.7 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KEZ44645.1 - 4.9 7.2 13.3 2.1 8.4 2.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.18 KEZ44646.1 - 1.5e-61 207.8 0.0 2.9e-61 206.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KEZ44646.1 - 1.2e-28 98.5 3.9 1.6e-16 59.7 0.3 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KEZ44646.1 - 2.7e-14 52.7 0.0 8.2e-14 51.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Med16 PF11635.3 KEZ44647.1 - 3.5e-113 379.1 0.0 4.9e-113 378.6 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 zf-CCCH_2 PF14608.1 KEZ44648.1 - 2.6e-09 36.7 48.9 4.1e-06 26.5 6.3 5.6 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KEZ44648.1 - 0.0055 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.19 KEZ44649.1 - 8.5e-23 81.1 0.0 1.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEZ44649.1 - 2.4e-12 46.6 0.1 1e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ44649.1 - 9.1e-09 34.6 0.0 2.7e-08 33.1 0.0 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ44649.1 - 0.00012 22.4 0.6 0.0027 18.0 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ44649.1 - 0.0041 17.1 0.0 0.083 12.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ44649.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KEZ44649.1 - 0.021 14.7 0.1 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ44649.1 - 0.021 14.6 0.1 0.05 13.3 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KEZ44649.1 - 0.023 13.3 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Ribul_P_3_epim PF00834.14 KEZ44649.1 - 0.23 10.5 0.0 0.38 9.8 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Med14 PF08638.6 KEZ44650.1 - 4.7e-62 208.7 0.0 9.9e-62 207.6 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 Ribosomal_L35Ae PF01247.13 KEZ44651.1 - 5.5e-42 141.4 0.4 6.2e-42 141.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KEZ44651.1 - 0.00048 19.9 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.4 KEZ44651.1 - 0.38 10.5 1.6 1.4 8.6 0.2 2.1 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) DUF2406 PF10295.4 KEZ44652.1 - 1.1e-14 54.6 0.4 2.8e-14 53.3 0.3 1.7 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 KEZ44653.1 - 2.1e-15 56.3 6.4 2.9e-15 55.9 4.4 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.18 KEZ44654.1 - 1.4e-54 184.8 0.0 2.5e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ44654.1 - 8.8e-13 47.9 0.0 2.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BSP_II PF05432.6 KEZ44654.1 - 1.3 8.2 8.2 0.029 13.6 0.7 1.8 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) DUF3602 PF12223.3 KEZ44655.1 - 2.4e-15 56.6 22.9 4.1e-12 46.3 4.5 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Glyco_hydro_10 PF00331.15 KEZ44656.1 - 3.3e-100 335.2 1.5 3.7e-100 335.0 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 zf-CCCH PF00642.19 KEZ44657.1 - 1.5e-10 40.4 8.1 3.2e-05 23.4 1.5 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KEZ44657.1 - 0.016 15.1 16.4 0.028 14.4 2.7 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type PP-binding PF00550.20 KEZ44658.1 - 1e-11 44.8 0.1 1.4e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KEZ44658.1 - 6.3e-05 22.9 0.1 9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_S30AE PF02482.14 KEZ44658.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.1 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF4232 PF14016.1 KEZ44658.1 - 0.066 12.8 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Fer4 PF00037.22 KEZ44659.1 - 3.8e-14 51.5 16.4 5.1e-08 32.1 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KEZ44659.1 - 3.5e-12 46.5 11.0 5.8e-12 45.8 7.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 KEZ44659.1 - 5e-10 39.9 8.2 0.00021 21.9 0.3 2.5 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 KEZ44659.1 - 6.5e-10 38.6 21.9 2.4e-08 33.6 8.4 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KEZ44659.1 - 8.8e-10 38.7 11.0 1.6e-09 37.8 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KEZ44659.1 - 1.6e-09 37.5 32.5 5.3e-06 26.1 8.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 KEZ44659.1 - 7e-09 35.5 31.1 6.7e-06 26.0 8.3 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KEZ44659.1 - 3.4e-08 32.9 15.0 0.00042 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KEZ44659.1 - 1e-07 31.5 17.0 0.00049 19.8 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KEZ44659.1 - 1.9e-06 28.0 9.5 0.00038 20.7 7.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 KEZ44659.1 - 3.7e-06 26.8 13.0 0.00043 20.3 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 KEZ44659.1 - 8.1e-06 26.1 9.1 0.0033 17.8 0.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KEZ44659.1 - 0.011 16.1 15.1 0.31 11.4 2.9 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 KEZ44659.1 - 0.017 15.6 13.2 0.31 11.6 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KEZ44659.1 - 0.034 14.6 17.7 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KEZ44659.1 - 0.12 12.5 4.9 0.28 11.3 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Mito_carr PF00153.22 KEZ44660.1 - 1.6e-56 187.9 3.6 5.6e-23 80.4 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.4 KEZ44662.1 - 5.5e-81 271.3 0.0 9.1e-81 270.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 KEZ44662.1 - 0.084 13.1 0.4 0.49 10.6 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) PCMT PF01135.14 KEZ44663.1 - 7.3e-59 198.8 0.0 9.6e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KEZ44663.1 - 2.1e-06 28.2 0.0 3.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44663.1 - 2.4e-06 27.1 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KEZ44663.1 - 7.3e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KEZ44663.1 - 0.00026 20.1 0.0 0.00046 19.3 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 KEZ44663.1 - 0.00099 18.8 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ44663.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44663.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DAGK_prokar PF01219.14 KEZ44663.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase Methyltransf_11 PF08241.7 KEZ44663.1 - 0.041 14.3 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KEZ44663.1 - 0.044 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 KEZ44663.1 - 0.06 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KEZ44663.1 - 0.076 12.0 0.0 0.099 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.8 KEZ44663.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 GMC_oxred_N PF00732.14 KEZ44664.1 - 4.8e-47 160.5 0.0 6.6e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ44664.1 - 3.2e-32 111.8 0.0 5.7e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ44664.1 - 0.0033 16.3 0.1 0.014 14.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ44664.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.13 KEZ44664.1 - 0.051 13.5 0.1 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.1 KEZ44664.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ44664.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GRIM-19 PF06212.7 KEZ44665.1 - 7.1e-21 74.2 0.0 8.6e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein Cnd1_N PF12922.2 KEZ44666.1 - 2.6e-57 193.2 3.5 7.7e-57 191.6 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KEZ44666.1 - 1.7e-53 181.0 5.4 1.4e-51 174.8 0.7 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KEZ44666.1 - 1.7e-09 37.8 2.5 0.00068 19.8 0.0 5.6 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KEZ44666.1 - 6.2e-07 28.9 9.3 0.071 13.2 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KEZ44666.1 - 0.0007 20.0 7.9 0.038 14.4 0.1 5.4 5 1 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.2 KEZ44666.1 - 0.0058 15.6 3.6 0.0086 15.0 0.3 3.0 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 KEZ44666.1 - 0.022 14.6 0.0 5 7.0 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2435) Pkinase PF00069.20 KEZ44667.1 - 2.7e-42 144.7 0.0 4.5e-38 130.8 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44667.1 - 5.7e-14 51.8 0.0 9.7e-08 31.3 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.18 KEZ44667.1 - 0.00021 21.1 0.1 0.034 13.8 0.0 2.9 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KEZ44667.1 - 0.00075 18.5 0.0 0.031 13.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Ribosomal_L18e PF00828.14 KEZ44668.1 - 5.2e-16 59.2 3.3 3.5e-13 50.0 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L18e/L15 Helicase_C_2 PF13307.1 KEZ44670.1 - 2.4e-57 193.5 0.0 7.3e-57 191.9 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KEZ44670.1 - 1.8e-47 161.0 0.0 3.2e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 KEZ44670.1 - 0.0027 17.5 0.1 1 9.1 0.0 2.7 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KEZ44670.1 - 0.094 11.5 1.5 0.28 9.9 1.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain DUF1136 PF06582.7 KEZ44670.1 - 0.94 9.2 3.5 2.5 7.8 2.4 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) GRAM PF02893.15 KEZ44671.1 - 1.6e-28 98.0 1.6 2.4e-16 58.9 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KEZ44671.1 - 1.2e-24 86.6 0.0 2.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KEZ44671.1 - 2e-14 53.6 0.1 5.7e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 KEZ44671.1 - 1.4e-07 31.4 0.3 6.4e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 KEZ44671.1 - 3.6e-07 30.4 0.2 9.8e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KEZ44671.1 - 2.1e-05 24.3 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 KEZ44671.1 - 8.1e-05 21.3 0.0 0.00017 20.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_6 PF15406.1 KEZ44671.1 - 0.034 14.1 0.1 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.27 KEZ44672.1 - 2.8e-15 55.4 8.4 0.00012 21.8 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat RTA1 PF04479.8 KEZ44673.1 - 5.2e-18 65.3 4.0 4.1e-17 62.4 2.8 2.0 1 1 0 1 1 1 1 RTA1 like protein DUF202 PF02656.10 KEZ44673.1 - 6.8 6.9 7.8 3.3 7.9 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Inp1 PF12634.2 KEZ44674.1 - 6.4e-36 123.2 0.0 6.7e-34 116.6 0.0 2.7 2 0 0 2 2 2 2 Inheritance of peroxisomes protein 1 Peptidase_M50 PF02163.17 KEZ44675.1 - 0.34 9.8 2.1 0.72 8.7 0.1 2.1 1 1 1 2 2 2 0 Peptidase family M50 Zn_clus PF00172.13 KEZ44676.1 - 1.7e-09 37.4 11.3 2.8e-09 36.7 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ44676.1 - 4.1e-05 22.5 0.0 7.8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.8 KEZ44676.1 - 1.1 9.1 16.9 2.2 8.1 11.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bromodomain PF00439.20 KEZ44677.1 - 8.7e-37 124.9 0.2 3.1e-19 68.6 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KEZ44677.1 - 2.4e-17 62.7 0.2 7e-17 61.2 0.1 1.9 2 0 0 2 2 2 1 BAH domain CDC45 PF02724.9 KEZ44677.1 - 3.8 5.4 26.0 0.0083 14.2 1.7 3.0 3 0 0 3 3 3 0 CDC45-like protein zf-C2H2_4 PF13894.1 KEZ44678.1 - 0.01 16.0 0.7 0.01 16.0 0.5 2.5 1 1 1 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ44678.1 - 0.067 13.5 2.6 0.38 11.1 1.8 2.2 1 1 0 1 1 1 0 Zinc finger, C2H2 type TPMT PF05724.6 KEZ44679.1 - 4.3e-27 94.9 0.0 7.9e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) adh_short PF00106.20 KEZ44679.1 - 1.2e-16 61.0 0.0 2.1e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.7 KEZ44679.1 - 9e-07 29.3 0.0 2.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ44679.1 - 1.1e-06 28.6 0.0 0.001 19.0 0.0 3.6 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ44679.1 - 1.5e-06 28.0 0.0 4.4e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44679.1 - 3.5e-06 27.5 0.0 1.9e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44679.1 - 1e-05 25.1 0.0 0.00023 20.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain KR PF08659.5 KEZ44679.1 - 1.4e-05 24.8 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_11 PF08241.7 KEZ44679.1 - 4.6e-05 23.8 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.1 KEZ44679.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_25 PF13649.1 KEZ44679.1 - 0.00012 22.4 0.0 0.014 15.7 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Metallophos PF00149.23 KEZ44679.1 - 0.039 13.3 1.3 0.1 12.0 0.9 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase TehB PF03848.9 KEZ44679.1 - 0.15 11.2 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ank_2 PF12796.2 KEZ44680.1 - 2.1e-13 50.3 0.1 4.5e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ44680.1 - 2.2e-11 42.9 0.1 6.1e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEZ44680.1 - 6.1e-11 42.2 0.3 4.9e-06 26.6 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ44680.1 - 4.9e-10 38.6 0.1 0.0022 18.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KEZ44680.1 - 4.1e-09 36.7 0.2 2.2e-07 31.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HTH_Tnp_Tc5 PF03221.11 KEZ44680.1 - 0.00045 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Nodulin_late PF07127.6 KEZ44680.1 - 0.14 12.2 6.2 0.059 13.4 0.9 2.4 2 0 0 2 2 2 0 Late nodulin protein adh_short PF00106.20 KEZ44682.1 - 2.3e-12 47.1 0.0 1.5e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase DNA_ligase_A_C PF04679.10 KEZ44682.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region KR PF08659.5 KEZ44682.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.1 2 1 0 2 2 2 0 KR domain AA_permease_2 PF13520.1 KEZ44683.1 - 1.6e-53 181.8 61.1 2e-53 181.4 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ44683.1 - 1.4e-23 83.0 55.4 1.9e-23 82.5 38.4 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 KEZ44684.1 - 3.2e-30 104.9 1.8 4.1e-30 104.6 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ44684.1 - 1.1e-07 31.6 10.7 2e-07 30.7 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 KEZ44685.1 - 2.4e-53 181.1 0.0 3.3e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ44685.1 - 1.2e-38 132.6 0.0 1.9e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KEZ44685.1 - 0.0004 20.3 0.3 0.0014 18.5 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ44685.1 - 0.00097 18.1 0.9 0.0061 15.5 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ44685.1 - 0.0016 17.4 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KEZ44685.1 - 0.024 13.5 0.3 0.67 8.7 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KEZ44685.1 - 0.042 12.4 0.0 0.06 11.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KEZ44685.1 - 0.067 13.0 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.1 KEZ44686.1 - 8.8e-30 103.5 46.4 1.8e-26 92.7 27.8 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 KEZ44686.1 - 2.2e-15 55.9 36.0 3.2e-14 52.1 20.0 2.1 2 0 0 2 2 2 2 Amino acid permease Peptidase_S8 PF00082.17 KEZ44687.1 - 1.1e-43 149.3 0.0 3.3e-43 147.8 0.0 1.8 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 KEZ44687.1 - 1.3e-17 64.2 0.3 3.1e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Amino_oxidase PF01593.19 KEZ44689.1 - 7e-36 124.2 0.0 6.4e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEZ44689.1 - 9.1e-12 44.8 0.4 2.9e-11 43.2 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ44689.1 - 1.4e-05 24.2 0.3 2.5e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ44689.1 - 0.0034 17.7 0.1 0.0081 16.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ44689.1 - 0.0041 16.2 1.3 0.007 15.4 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KEZ44689.1 - 0.0062 15.4 0.3 0.013 14.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KEZ44689.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ44689.1 - 0.0081 14.6 0.2 0.014 13.8 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ44689.1 - 0.048 13.5 0.2 0.082 12.7 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ44689.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 KEZ44689.1 - 0.068 12.2 0.2 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Methyltransf_23 PF13489.1 KEZ44690.1 - 8.4e-18 64.6 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44690.1 - 4.1e-12 46.4 0.0 8.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44690.1 - 1.5e-08 34.3 0.0 1.3e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44690.1 - 8e-08 32.8 0.0 4.7e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44690.1 - 3.1e-07 30.7 0.0 1.4e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44690.1 - 5.1e-06 26.7 0.0 1.3e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ44690.1 - 1.3e-05 24.5 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KEZ44690.1 - 1.4e-05 24.3 0.0 0.00014 21.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEZ44690.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ44690.1 - 0.032 14.2 0.0 0.21 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KEZ44690.1 - 0.036 13.6 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 KEZ44690.1 - 0.04 13.0 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KEZ44690.1 - 0.092 11.7 0.0 0.21 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KEZ44690.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Sugar_tr PF00083.19 KEZ44691.1 - 7.8e-105 351.0 25.8 9e-105 350.8 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ44691.1 - 1.3e-22 80.0 33.2 8.1e-15 54.3 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4246 PF14033.1 KEZ44692.1 - 3.4e-162 540.5 0.0 4.5e-162 540.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KEZ44692.1 - 0.0018 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-Fe_Oxy_2 PF10014.4 KEZ44692.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase S-antigen PF05756.6 KEZ44692.1 - 0.38 10.7 7.0 0.84 9.6 4.8 1.5 1 0 0 1 1 1 0 S-antigen protein tRNA-synt_1d PF00750.14 KEZ44693.1 - 4e-47 160.7 0.0 1e-46 159.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KEZ44693.1 - 2e-10 40.6 0.0 4.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain AAA PF00004.24 KEZ44694.1 - 3e-11 43.6 0.0 6.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HNH_2 PF13391.1 KEZ44696.1 - 1.5e-05 24.6 0.1 2.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease CFEM PF05730.6 KEZ44699.1 - 4.9e-07 29.4 5.9 7.1e-07 28.9 4.1 1.2 1 0 0 1 1 1 1 CFEM domain IER PF05760.7 KEZ44699.1 - 0.28 11.0 2.7 0.31 10.9 1.8 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) HNH_2 PF13391.1 KEZ44700.1 - 4e-11 42.5 0.1 9.5e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Alk_phosphatase PF00245.15 KEZ44700.1 - 0.13 10.9 0.1 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase Med18 PF09637.5 KEZ44701.1 - 1.5e-21 77.0 0.0 1.8e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.6 KEZ44702.1 - 2.4e-55 186.3 0.0 3.5e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KEZ44702.1 - 1.5e-28 99.4 0.0 6e-28 97.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KEZ44702.1 - 4e-07 29.5 0.0 0.00086 18.5 0.0 2.5 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 KEZ44702.1 - 0.00023 21.3 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ44702.1 - 0.00046 20.9 0.0 0.003 18.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEZ44702.1 - 0.00072 18.7 0.0 0.0029 16.7 0.0 1.9 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.1 KEZ44702.1 - 0.068 13.4 0.0 2.1 8.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 KEZ44702.1 - 0.098 11.8 0.0 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KEZ44702.1 - 0.11 12.6 0.0 0.84 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF3046 PF11248.3 KEZ44702.1 - 0.13 12.3 0.3 3.5 7.6 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3046) DUF2638 PF10937.3 KEZ44703.1 - 6.6e-36 123.7 0.2 8e-36 123.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DOMON PF03351.12 KEZ44704.1 - 0.0001 22.1 0.1 0.0002 21.2 0.1 1.4 1 0 0 1 1 1 1 DOMON domain FAD_binding_4 PF01565.18 KEZ44705.1 - 2.4e-08 33.5 0.1 3.4e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.9 KEZ44705.1 - 2.5e-08 33.8 0.1 3.3e-07 30.1 0.1 2.3 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase mIF3 PF14877.1 KEZ44705.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Rxt3 PF08642.5 KEZ44706.1 - 3.2e-29 101.5 0.0 7.2e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KEZ44706.1 - 0.00014 21.7 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 LCCL domain NicO PF03824.11 KEZ44706.1 - 9.6 5.4 6.6 20 4.3 4.6 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein PI3K_p85B PF02192.11 KEZ44707.1 - 0.099 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain SDF PF00375.13 KEZ44708.1 - 2.1e-92 309.8 33.8 2.6e-92 309.5 23.4 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.1 KEZ44708.1 - 0.0089 15.6 0.3 0.0089 15.6 0.2 2.6 3 1 0 3 3 3 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF4381 PF14316.1 KEZ44708.1 - 0.31 11.1 2.1 3 7.9 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) GHMP_kinases_N PF00288.21 KEZ44709.1 - 1.9e-10 40.6 0.9 5.9e-10 39.0 0.6 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain PDGLE PF13190.1 KEZ44709.1 - 0.05 13.2 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 PDGLE domain DUF647 PF04884.9 KEZ44710.1 - 1.9e-83 279.5 0.4 2.7e-83 279.0 0.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.12 KEZ44711.1 - 1.2e-82 277.3 0.0 1.7e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Acetyltransf_8 PF13523.1 KEZ44711.1 - 3.3e-24 85.4 0.0 6e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Taeniidae_ag PF05596.6 KEZ44711.1 - 0.26 11.1 0.0 0.53 10.1 0.0 1.4 1 0 0 1 1 1 0 Taeniidae antigen CTP_transf_2 PF01467.21 KEZ44712.1 - 1.2e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase PHO4 PF01384.15 KEZ44713.1 - 1.1e-107 359.5 14.4 8.6e-107 356.5 10.0 1.9 1 1 0 1 1 1 1 Phosphate transporter family SPX PF03105.14 KEZ44714.1 - 3.9e-43 148.2 1.4 4.3e-42 144.7 0.0 2.8 2 1 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 KEZ44714.1 - 1.7e-29 103.0 38.5 2.5e-29 102.4 26.7 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region PPTA PF01239.17 KEZ44714.1 - 2.1e-28 96.4 9.7 6.5e-08 31.5 0.6 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat CitMHS PF03600.11 KEZ44714.1 - 1.6e-17 63.1 27.0 2.6e-11 42.7 17.4 2.3 2 0 0 2 2 2 2 Citrate transporter ABC_membrane PF00664.18 KEZ44715.1 - 3.8e-76 256.1 27.7 6.6e-44 150.3 5.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ44715.1 - 2.3e-65 219.0 0.0 7.6e-32 110.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ44715.1 - 1.4e-14 53.8 0.4 0.00026 20.3 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ44715.1 - 4.7e-12 46.4 0.0 0.024 14.6 0.0 4.4 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 KEZ44715.1 - 8.4e-09 34.8 0.3 0.0023 17.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KEZ44715.1 - 7.6e-07 28.4 0.0 0.029 13.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ44715.1 - 7.8e-07 29.9 0.0 0.081 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KEZ44715.1 - 2.7e-06 26.2 0.1 0.00035 19.2 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 KEZ44715.1 - 5.5e-06 25.9 0.1 0.19 11.1 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 KEZ44715.1 - 9.7e-06 25.7 3.1 0.16 12.0 0.0 4.3 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ44715.1 - 1.7e-05 24.8 5.4 0.0038 17.2 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 KEZ44715.1 - 0.00014 21.6 2.7 0.33 10.9 0.1 3.8 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 KEZ44715.1 - 0.00023 21.5 0.3 0.21 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 KEZ44715.1 - 0.00034 20.5 1.0 0.02 14.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KEZ44715.1 - 0.00066 19.2 1.5 0.19 11.1 0.1 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_30 PF13604.1 KEZ44715.1 - 0.00097 18.7 1.2 0.48 9.9 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 KEZ44715.1 - 0.0028 17.8 0.8 5 7.3 0.1 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ44715.1 - 0.005 16.5 0.4 5 6.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KEZ44715.1 - 0.012 15.8 0.1 3.3 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEZ44715.1 - 0.018 14.9 0.4 9.8 6.0 0.1 3.0 3 0 0 3 3 2 0 AAA domain DUF3987 PF13148.1 KEZ44715.1 - 0.021 13.3 0.0 1.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FtsK_SpoIIIE PF01580.13 KEZ44715.1 - 0.031 13.7 0.0 0.49 9.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KEZ44715.1 - 0.12 11.8 0.5 8.3 5.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KEZ44715.1 - 0.13 12.4 0.1 26 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Pyr_redox PF00070.22 KEZ44716.1 - 2.1e-15 56.8 0.7 2e-12 47.3 0.7 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ44716.1 - 1.5e-10 41.3 0.1 0.00054 19.9 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ44716.1 - 1.9e-07 31.3 0.0 0.0045 17.0 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ44716.1 - 0.00011 21.2 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.1 KEZ44716.1 - 0.00015 20.8 0.0 0.00037 19.5 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KEZ44716.1 - 0.023 13.1 2.0 0.099 11.0 0.1 2.6 2 1 1 3 3 3 0 HI0933-like protein DAO PF01266.19 KEZ44716.1 - 0.025 13.4 0.3 0.025 13.4 0.2 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEZ44716.1 - 0.041 12.9 2.2 1.2 8.1 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 KEZ44716.1 - 0.072 11.9 0.0 1.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KEZ44716.1 - 0.18 10.3 0.1 0.87 8.1 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.1 KEZ44716.1 - 0.22 11.8 2.4 1.2 9.3 0.4 2.6 3 1 0 3 3 3 0 Putative NAD(P)-binding AMP-binding PF00501.23 KEZ44717.1 - 2.9e-94 315.8 0.0 3.4e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ44717.1 - 6.3e-12 46.2 0.0 1.3e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PAPA-1 PF04795.7 KEZ44719.1 - 2.3e-24 85.8 3.1 2.3e-24 85.8 2.1 3.0 3 1 0 3 3 3 1 PAPA-1-like conserved region LptE PF04390.7 KEZ44719.1 - 0.016 14.9 0.6 0.032 13.9 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Pex14_N PF04695.8 KEZ44720.1 - 8.8e-20 71.1 0.8 5.7e-19 68.5 0.0 2.2 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.14 KEZ44720.1 - 0.15 12.4 0.3 0.15 12.4 0.2 2.5 2 2 1 3 3 3 0 60s Acidic ribosomal protein CitF PF04223.7 KEZ44720.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Chromo PF00385.19 KEZ44721.1 - 4.7e-08 32.5 0.3 9.7e-08 31.5 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.17 KEZ44722.1 - 6.3e-62 207.7 0.0 7.5e-62 207.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ44722.1 - 1.6e-20 73.8 0.0 2.4e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ44722.1 - 8e-12 44.7 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KEZ44722.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KEZ44722.1 - 0.0002 21.4 0.1 0.00044 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KEZ44722.1 - 0.0006 19.3 0.0 0.0014 18.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KEZ44722.1 - 0.0012 18.0 0.1 0.0021 17.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 KEZ44722.1 - 0.0028 16.7 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KEZ44722.1 - 0.0046 16.1 0.1 0.01 15.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 KEZ44722.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ44722.1 - 0.0092 15.9 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 KEZ44722.1 - 0.04 13.1 0.0 0.072 12.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 KEZ44722.1 - 0.083 13.1 0.1 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Brix PF04427.13 KEZ44723.1 - 2.3e-33 115.4 0.0 3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain F-box PF00646.28 KEZ44724.1 - 9e-07 28.3 0.0 2.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KEZ44724.1 - 1.3e-05 24.8 0.3 0.00029 20.5 0.0 2.6 2 0 0 2 2 2 1 F-box-like Hist_deacetyl PF00850.14 KEZ44725.1 - 1.6e-92 310.1 0.1 2.4e-92 309.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KEZ44725.1 - 8.5e-36 123.0 0.0 1.3e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain IncA PF04156.9 KEZ44726.1 - 0.27 10.7 5.7 0.48 9.9 3.9 1.3 1 0 0 1 1 1 0 IncA protein zf-HC5HC2H PF13771.1 KEZ44727.1 - 1.9e-05 24.7 2.8 4.4e-05 23.5 1.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KEZ44727.1 - 7.2e-05 22.7 2.1 0.0002 21.3 1.5 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain VEFS-Box PF09733.4 KEZ44727.1 - 0.00024 20.7 0.1 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.24 KEZ44727.1 - 0.00047 19.8 8.3 0.0012 18.5 5.8 1.7 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 KEZ44727.1 - 0.029 14.3 7.9 0.019 14.9 3.6 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain ADK_lid PF05191.9 KEZ44727.1 - 0.12 12.0 2.3 0.39 10.4 1.3 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING-like PF08746.6 KEZ44727.1 - 0.2 11.6 7.4 0.53 10.3 5.1 1.8 1 0 0 1 1 1 0 RING-like domain zf-rbx1 PF12678.2 KEZ44727.1 - 0.26 11.4 4.0 0.97 9.5 2.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 KEZ44727.1 - 1 9.2 10.0 0.53 10.1 5.0 2.1 2 0 0 2 2 2 0 Ring finger domain TPT PF03151.11 KEZ44728.1 - 1.9e-38 131.5 1.8 1.9e-38 131.5 1.2 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KEZ44728.1 - 2.2e-10 39.9 10.2 1.2e-09 37.5 7.1 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEZ44728.1 - 3e-05 24.0 27.7 0.0017 18.3 6.1 3.1 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KEZ44728.1 - 0.0035 16.4 0.0 0.53 9.3 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter ORC5_C PF14630.1 KEZ44729.1 - 2.6e-76 256.6 0.0 3.3e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 KEZ44729.1 - 3.4e-11 43.4 0.1 1.8e-10 41.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KEZ44729.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KEZ44729.1 - 0.0093 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEZ44729.1 - 0.019 15.1 0.0 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KEZ44729.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Esterase_phd PF10503.4 KEZ44730.1 - 3.1e-20 72.3 1.3 3.4e-20 72.2 0.1 1.5 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEZ44730.1 - 4e-06 26.1 0.2 6.1e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEZ44730.1 - 4.6e-06 26.3 0.0 7.8e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 KEZ44730.1 - 0.00012 20.7 0.2 0.038 12.4 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 KEZ44730.1 - 0.00027 20.9 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ44730.1 - 0.0012 18.6 0.1 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ44730.1 - 0.0036 16.9 0.5 0.0077 15.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KEZ44730.1 - 0.0057 16.1 1.1 0.018 14.4 0.8 1.9 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KEZ44730.1 - 0.0063 15.9 0.1 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Birna_VP5 PF03042.9 KEZ44730.1 - 0.048 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP5 protein BAAT_C PF08840.6 KEZ44730.1 - 0.13 11.9 0.2 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal ATP-synt_ab PF00006.20 KEZ44731.1 - 5.4e-62 209.1 0.0 7.9e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEZ44731.1 - 9.3e-26 90.5 0.7 1.6e-25 89.7 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEZ44731.1 - 1.6e-23 82.6 0.3 1.1e-22 79.9 0.2 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 KEZ44731.1 - 0.0063 15.9 0.4 0.054 12.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KEZ44731.1 - 0.0066 16.1 0.0 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 KEZ44731.1 - 0.0079 15.9 0.2 1.1 9.0 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KEZ44731.1 - 0.016 14.4 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 KEZ44731.1 - 0.018 15.2 0.1 0.6 10.3 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KEZ44731.1 - 0.023 14.3 0.1 0.063 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 KEZ44731.1 - 0.024 13.7 0.1 0.039 13.0 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KEZ44731.1 - 0.028 14.4 0.3 0.22 11.5 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KEZ44731.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 KEZ44731.1 - 0.074 13.1 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEZ44731.1 - 0.11 11.2 0.6 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 KEZ44732.1 - 6.4e-26 90.3 0.1 2.3e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 KEZ44732.1 - 2e-19 70.1 0.1 5.3e-14 52.3 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 KEZ44732.1 - 1.6e-18 66.5 0.0 5.2e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AAA_2 PF07724.9 KEZ44733.1 - 2.2e-33 115.5 0.0 8.7e-33 113.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KEZ44733.1 - 3e-12 46.8 0.0 6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KEZ44733.1 - 2.1e-08 33.9 0.0 4.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KEZ44733.1 - 1.5e-07 31.1 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.18 KEZ44733.1 - 0.00026 19.9 1.2 0.00031 19.6 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family AAA_14 PF13173.1 KEZ44733.1 - 0.0013 18.6 0.7 0.0021 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEZ44733.1 - 0.0024 17.2 0.1 0.0061 15.9 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 KEZ44733.1 - 0.0046 17.0 0.7 0.071 13.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ44733.1 - 0.0058 17.4 0.4 0.024 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ44733.1 - 0.0091 16.0 0.2 0.1 12.5 0.0 2.3 1 1 2 3 3 3 1 AAA ATPase domain T2SE PF00437.15 KEZ44733.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 KEZ44733.1 - 0.038 13.1 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KEZ44733.1 - 0.044 14.0 0.2 0.1 12.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 KEZ44733.1 - 0.064 12.7 0.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Torsin PF06309.6 KEZ44733.1 - 0.073 12.9 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_24 PF13479.1 KEZ44733.1 - 0.15 11.6 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEZ44733.1 - 0.19 12.0 1.7 0.33 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain COX4 PF02936.9 KEZ44734.1 - 1.8e-44 150.9 0.0 2.3e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Toprim_Crpt PF13342.1 KEZ44734.1 - 0.032 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF1104 PF06518.6 KEZ44734.1 - 0.16 12.1 0.4 0.35 11.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Mus7 PF09462.5 KEZ44735.1 - 1.4e-114 384.2 0.0 1.4e-114 384.2 0.0 1.7 2 0 0 2 2 2 1 Mus7/MMS22 family Autophagy_Cterm PF10381.4 KEZ44735.1 - 0.14 11.3 0.2 0.29 10.2 0.1 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal TFIIH_BTF_p62_N PF08567.6 KEZ44736.1 - 2e-24 85.0 0.0 7.5e-24 83.1 0.0 2.1 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 KEZ44736.1 - 3.2e-16 58.8 0.8 3.2e-12 46.0 0.0 3.2 2 1 0 2 2 2 2 BSD domain Transket_pyr PF02779.19 KEZ44738.1 - 5.6e-61 205.1 0.0 9.1e-61 204.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KEZ44738.1 - 3.4e-56 190.1 0.0 5.1e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_15 PF00723.16 KEZ44739.1 - 3.6e-78 263.1 0.0 2.9e-39 134.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KEZ44739.1 - 7.5e-26 89.5 0.1 1.3e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.8 KEZ44740.1 - 2.8e-153 511.5 59.3 3.2e-153 511.3 41.1 1.0 1 0 0 1 1 1 1 SART-1 family LEA_2 PF03168.8 KEZ44742.1 - 2.4e-08 34.2 0.5 0.05 13.9 0.1 4.3 4 0 0 4 4 4 2 Late embryogenesis abundant protein DUF3712 PF12505.3 KEZ44742.1 - 2.5e-07 30.7 1.3 1.3e-06 28.4 0.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) KH_1 PF00013.24 KEZ44743.1 - 1.5e-09 37.3 0.1 4.5e-08 32.6 0.1 2.3 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KEZ44743.1 - 1.7e-06 27.4 0.1 0.00017 21.1 0.0 2.8 2 0 0 2 2 2 1 KH domain ALS_ss_C PF10369.4 KEZ44744.1 - 8.1e-19 67.1 0.0 2e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KEZ44744.1 - 6.7e-13 47.8 0.2 1.3e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KEZ44744.1 - 3.4e-11 42.7 0.0 6.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 KEZ44744.1 - 0.11 12.1 0.5 20 4.9 0.0 2.9 3 0 0 3 3 3 0 ACT domain DUF974 PF06159.8 KEZ44745.1 - 1.3e-80 270.4 0.0 2.2e-80 269.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) IMS PF00817.15 KEZ44746.1 - 5.6e-35 120.3 0.0 8.8e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KEZ44746.1 - 7.7e-11 42.0 0.1 1.6e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain KOW PF00467.24 KEZ44747.1 - 5.3e-08 32.2 3.4 6.6e-08 31.9 1.3 1.9 2 0 0 2 2 2 1 KOW motif CtaG_Cox11 PF04442.9 KEZ44748.1 - 1.8e-57 193.4 0.1 3e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 NAD_binding_8 PF13450.1 KEZ44749.1 - 3.3e-13 49.4 0.3 1.2e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KEZ44749.1 - 2.4e-11 43.3 0.0 3.8e-05 22.9 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.19 KEZ44749.1 - 3.6e-06 26.1 0.2 0.00011 21.2 0.0 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ44749.1 - 1.1e-05 25.6 0.1 0.001 19.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ44749.1 - 0.0011 18.7 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEZ44749.1 - 0.0024 16.7 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ44749.1 - 0.0025 16.3 0.1 0.037 12.4 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KEZ44749.1 - 0.0036 17.6 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ44749.1 - 0.023 14.6 0.0 0.051 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ44749.1 - 0.036 12.9 0.1 0.051 12.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KEZ44749.1 - 0.044 13.3 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KEZ44749.1 - 0.15 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase OTCace_N PF02729.16 KEZ44750.1 - 3e-40 137.1 0.4 4.4e-40 136.6 0.3 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KEZ44750.1 - 9.2e-38 129.5 0.0 1.5e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain V-SNARE PF05008.10 KEZ44751.1 - 7.6e-21 74.0 2.6 7.6e-21 74.0 1.8 2.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KEZ44751.1 - 7.3e-17 61.1 1.6 7.3e-17 61.1 1.1 2.5 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KEZ44751.1 - 0.0082 15.8 1.0 0.016 14.8 0.2 1.9 2 0 0 2 2 2 1 Sec20 Phycobilisome PF00502.14 KEZ44751.1 - 0.04 13.6 0.3 0.089 12.5 0.2 1.6 1 0 0 1 1 1 0 Phycobilisome protein Spc7 PF08317.6 KEZ44751.1 - 0.047 12.3 2.7 0.77 8.3 0.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Fusion_gly PF00523.13 KEZ44751.1 - 0.078 11.0 3.9 0.3 9.1 0.1 2.3 3 0 0 3 3 3 0 Fusion glycoprotein F0 TBCA PF02970.11 KEZ44751.1 - 0.08 13.0 3.2 5.2 7.2 0.5 2.8 2 1 0 2 2 2 0 Tubulin binding cofactor A Synaptobrevin PF00957.16 KEZ44751.1 - 0.15 11.6 2.1 0.33 10.5 0.9 2.0 1 1 1 2 2 2 0 Synaptobrevin Use1 PF09753.4 KEZ44751.1 - 0.57 9.5 5.2 10 5.4 3.6 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Ala_racemase_N PF01168.15 KEZ44754.1 - 4.5e-40 137.5 0.0 5.7e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 KEZ44755.1 - 2e-118 396.0 5.1 2.3e-118 395.7 3.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KEZ44755.1 - 1.2e-45 154.0 0.0 2.7e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KEZ44755.1 - 1.9e-18 66.8 0.0 3.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Methyltransf_23 PF13489.1 KEZ44756.1 - 8.1e-10 38.6 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44756.1 - 2.6e-09 37.4 0.0 6.7e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44756.1 - 2.6e-07 31.0 0.0 4.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44756.1 - 1.9e-05 24.3 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44756.1 - 0.0012 19.1 0.0 0.0029 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44756.1 - 0.002 17.2 0.0 0.0043 16.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KEZ44756.1 - 0.031 14.8 0.0 0.14 12.7 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain P16-Arc PF04699.9 KEZ44757.1 - 2.4e-38 131.5 0.0 3.6e-30 104.9 0.0 2.0 1 1 1 2 2 2 2 ARP2/3 complex 16 kDa subunit (p16-Arc) RunxI PF08504.6 KEZ44757.1 - 0.008 16.6 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Runx inhibition domain CN_hydrolase PF00795.17 KEZ44758.1 - 1.2e-24 86.7 0.0 2.3e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.9 KEZ44758.1 - 6.5e-13 48.5 1.4 1.6e-05 24.3 0.5 2.7 3 0 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 KEZ44759.1 - 1.4e-70 236.9 0.0 3.8e-68 229.0 0.0 2.4 3 0 0 3 3 3 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KEZ44759.1 - 2.3e-32 111.5 0.0 4.3e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KEZ44759.1 - 9.2e-15 54.7 0.2 1.9e-14 53.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KEZ44759.1 - 7.1e-14 51.7 0.6 1.4e-13 50.8 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KEZ44759.1 - 5.1e-11 42.2 0.2 1.1e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KEZ44759.1 - 4.9e-06 26.3 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Herpes_UL21 PF03252.8 KEZ44759.1 - 0.032 12.7 0.0 0.049 12.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL21 V_ATPase_I PF01496.14 KEZ44760.1 - 5.9e-291 966.8 0.2 6.9e-291 966.6 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family LRR_4 PF12799.2 KEZ44760.1 - 0.0044 16.6 4.0 3.8 7.2 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) DUF1465 PF07323.7 KEZ44760.1 - 0.0093 15.5 0.1 0.24 10.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) LRR_6 PF13516.1 KEZ44760.1 - 0.039 14.0 1.8 5.6 7.3 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich repeat IncA PF04156.9 KEZ44760.1 - 0.089 12.3 1.7 0.21 11.1 0.1 2.1 2 0 0 2 2 2 0 IncA protein LRR_7 PF13504.1 KEZ44760.1 - 0.096 12.9 3.3 6.9 7.3 0.0 5.3 6 0 0 6 6 4 0 Leucine rich repeat DUF342 PF03961.8 KEZ44760.1 - 0.14 10.5 0.1 0.28 9.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Filament PF00038.16 KEZ44760.1 - 0.3 10.4 4.2 5.1 6.4 0.3 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF2852 PF11014.3 KEZ44760.1 - 0.32 10.9 2.0 6.6 6.7 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) LRR_1 PF00560.28 KEZ44760.1 - 0.36 11.0 3.6 17 5.9 0.0 5.3 6 1 1 7 7 5 0 Leucine Rich Repeat DUF4201 PF13870.1 KEZ44760.1 - 9.1 5.6 7.0 23 4.3 0.1 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) PHD PF00628.24 KEZ44761.1 - 9.5e-10 38.0 8.5 1.7e-09 37.2 5.9 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KEZ44761.1 - 1.1e-08 35.3 0.1 1.1e-08 35.3 0.1 2.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 KEZ44761.1 - 0.036 14.2 1.3 0.091 12.9 0.9 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prenyltransf PF01255.14 KEZ44762.1 - 2.5e-88 294.9 0.1 1e-87 292.9 0.0 1.7 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF1751 PF08551.5 KEZ44763.1 - 1.3e-05 25.4 1.0 2.4e-05 24.6 0.5 1.7 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KEZ44763.1 - 3.9e-05 23.7 0.1 8.5e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 KEZ44763.1 - 0.021 14.3 2.8 0.031 13.7 1.9 1.2 1 0 0 1 1 1 0 Der1-like family TFIID-18kDa PF02269.11 KEZ44764.1 - 5.6e-18 64.5 0.0 8.5e-18 63.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 KEZ44764.1 - 4.1e-05 23.6 0.0 8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KEZ44764.1 - 0.00014 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KEZ44764.1 - 0.00076 19.4 1.3 0.006 16.6 0.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KEZ44764.1 - 0.0015 18.1 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 KEZ44764.1 - 0.044 14.0 0.1 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Uds1 PF15456.1 KEZ44765.1 - 3.9e-44 149.6 3.2 3.9e-44 149.6 2.2 8.9 5 1 3 9 9 9 2 Up-regulated During Septation MOSC PF03473.12 KEZ44765.1 - 0.0041 16.5 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 MOSC domain Img2 PF05046.9 KEZ44765.1 - 0.0066 16.6 4.1 0.033 14.4 0.3 3.4 2 1 1 3 3 3 1 Mitochondrial large subunit ribosomal protein (Img2) Filament PF00038.16 KEZ44765.1 - 0.0075 15.7 1.3 0.0075 15.7 0.9 6.0 5 1 0 6 6 6 3 Intermediate filament protein IncA PF04156.9 KEZ44765.1 - 0.25 10.9 102.2 0.48 9.9 11.0 8.7 4 2 4 8 8 8 0 IncA protein Tropomyosin_1 PF12718.2 KEZ44765.1 - 4.3 7.1 91.9 0.15 11.9 1.5 9.1 6 1 3 9 9 9 0 Tropomyosin like TRAP-gamma PF07074.7 KEZ44765.1 - 7.8 5.9 8.6 0.87 9.0 1.2 2.4 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Ric8 PF10165.4 KEZ44766.1 - 4.1e-73 246.7 0.0 5.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn TIP49 PF06068.8 KEZ44767.1 - 1.6e-186 619.8 0.1 1.9e-186 619.5 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KEZ44767.1 - 7.2e-11 42.4 0.4 6.6e-07 29.5 0.1 2.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KEZ44767.1 - 2.6e-10 39.7 0.1 1.3e-06 27.6 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEZ44767.1 - 2.7e-05 24.2 0.1 0.18 11.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEZ44767.1 - 3e-05 23.6 0.2 9.1e-05 22.1 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_16 PF13191.1 KEZ44767.1 - 0.00015 21.7 0.0 0.063 13.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 KEZ44767.1 - 0.00045 20.2 0.1 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ44767.1 - 0.0031 17.2 0.3 0.17 11.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KEZ44767.1 - 0.0057 16.0 0.1 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEZ44767.1 - 0.0086 15.1 0.3 0.024 13.7 0.2 1.7 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 KEZ44767.1 - 0.015 14.4 0.1 0.55 9.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEZ44767.1 - 0.029 13.8 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 KEZ44767.1 - 0.031 13.7 0.2 0.065 12.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KEZ44767.1 - 0.035 14.4 0.1 0.071 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ44767.1 - 0.036 13.0 0.1 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 KEZ44767.1 - 0.067 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 KEZ44767.1 - 0.096 13.5 0.1 0.2 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.14 KEZ44768.1 - 2.3e-22 79.0 1.0 4.6e-22 78.0 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KEZ44768.1 - 1.9e-06 28.1 0.5 3.9e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain ALF PF03752.8 KEZ44768.1 - 0.1 12.4 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Short repeats of unknown function Dynactin PF12455.3 KEZ44769.1 - 3.7e-87 291.7 7.2 3.7e-87 291.7 5.0 2.9 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 KEZ44769.1 - 1.8e-22 78.7 0.4 3.4e-22 77.8 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain Zn_clus PF00172.13 KEZ44770.1 - 7.5e-07 28.9 11.1 1.6e-06 27.9 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CC PF04942.9 KEZ44770.1 - 0.03 14.2 1.0 0.092 12.6 0.7 1.8 1 0 0 1 1 1 0 CC domain CDP-OH_P_transf PF01066.16 KEZ44771.1 - 1.2e-18 67.3 3.9 1.2e-18 67.3 2.7 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Het-C PF07217.6 KEZ44773.1 - 3.5e-273 907.3 0.0 4.5e-273 906.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cyt-b5 PF00173.23 KEZ44774.1 - 5.7e-17 61.2 0.7 1.5e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KEZ44774.1 - 3.6e-08 33.8 22.9 3.6e-08 33.8 15.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1453 PF07301.6 KEZ44774.1 - 0.0046 16.8 0.1 0.0073 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1453) COX14 PF14880.1 KEZ44774.1 - 0.15 11.7 0.4 0.38 10.4 0.3 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RRM_1 PF00076.17 KEZ44775.1 - 7.1e-44 147.3 1.8 8.5e-21 73.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ44775.1 - 2.4e-34 117.1 0.3 4.2e-17 61.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KEZ44775.1 - 1.6e-30 105.1 0.1 3.6e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KEZ44775.1 - 4.3e-20 71.2 0.1 2.6e-07 30.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KEZ44775.1 - 0.0055 16.5 0.6 0.062 13.1 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif DUF1866 PF08952.6 KEZ44775.1 - 0.074 12.5 0.0 6.6 6.2 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.1 KEZ44775.1 - 0.14 11.9 0.0 11 5.9 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Aminotran_1_2 PF00155.16 KEZ44777.1 - 1.3e-33 116.5 0.0 3.6e-33 114.9 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class I and II VWA_2 PF13519.1 KEZ44778.1 - 2.2e-09 37.6 0.0 3.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEZ44778.1 - 6.3e-09 35.7 0.0 1.6e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KEZ44778.1 - 7.4e-06 25.9 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus XPG_I PF00867.13 KEZ44779.1 - 4.8e-25 87.4 0.0 9.7e-25 86.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KEZ44779.1 - 7.5e-08 32.5 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Nucleo_P87 PF07267.6 KEZ44779.1 - 1.1 7.8 2.3 1.8 7.1 1.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_C12 PF01088.16 KEZ44781.1 - 2.2e-51 174.0 0.0 3.2e-50 170.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Actin PF00022.14 KEZ44782.1 - 2.5e-20 72.2 0.0 2.7e-19 68.8 0.0 2.6 2 1 0 2 2 2 1 Actin Acetyltransf_2 PF00797.12 KEZ44782.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase WW PF00397.21 KEZ44783.1 - 1.9e-06 27.6 0.2 3.7e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 WW domain Pga1 PF10333.4 KEZ44784.1 - 1.6e-05 24.6 0.1 3.7e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator His_biosynth PF00977.16 KEZ44785.1 - 2.8e-37 128.1 0.0 3.5e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 KEZ44785.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Tubulin PF00091.20 KEZ44786.1 - 3.2e-69 233.0 0.0 4.4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KEZ44786.1 - 3.7e-49 165.9 0.1 6.1e-49 165.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KEZ44786.1 - 0.0066 15.9 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain EF-hand_4 PF12763.2 KEZ44787.1 - 7.4e-34 115.6 0.0 2.1e-13 49.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KEZ44787.1 - 5.7e-07 29.5 0.0 0.0034 17.5 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KEZ44787.1 - 8.4e-05 21.6 0.3 0.39 10.1 0.0 4.6 4 0 0 4 4 4 1 EF hand Reo_sigmaC PF04582.7 KEZ44787.1 - 0.0005 19.3 11.8 0.0056 15.8 1.5 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein ATG16 PF08614.6 KEZ44787.1 - 0.002 18.0 21.2 0.002 18.0 14.7 2.8 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) UBA PF00627.26 KEZ44787.1 - 0.002 17.8 0.0 0.0058 16.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 KEZ44787.1 - 0.002 17.8 0.5 7.3 6.7 0.0 4.9 5 0 0 5 5 5 0 EF-hand domain IncA PF04156.9 KEZ44787.1 - 0.0035 16.9 28.8 0.15 11.6 6.8 2.2 1 1 1 2 2 2 2 IncA protein Spc7 PF08317.6 KEZ44787.1 - 0.0036 16.0 25.8 0.11 11.0 8.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF812 PF05667.6 KEZ44787.1 - 0.0058 15.2 16.5 0.014 13.9 11.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF812) WEMBL PF05701.6 KEZ44787.1 - 0.0066 14.9 24.8 0.011 14.2 17.2 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF3584 PF12128.3 KEZ44787.1 - 0.016 12.5 26.1 0.023 12.0 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 KEZ44787.1 - 0.017 14.9 29.9 0.036 13.9 7.5 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_8 PF13833.1 KEZ44787.1 - 0.021 14.4 0.0 6.4 6.4 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair TBPIP PF07106.8 KEZ44787.1 - 0.055 13.0 24.3 0.14 11.7 5.6 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KEZ44787.1 - 0.089 12.6 12.1 0.016 15.0 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MAD PF05557.8 KEZ44787.1 - 0.094 10.7 25.5 0.14 10.2 17.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TPR_MLP1_2 PF07926.7 KEZ44787.1 - 0.27 10.9 32.3 0.95 9.2 12.1 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 KEZ44787.1 - 0.33 10.2 40.9 0.61 9.3 9.2 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF869 PF05911.6 KEZ44787.1 - 0.35 9.0 21.8 0.59 8.2 15.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Myosin_tail_1 PF01576.14 KEZ44787.1 - 0.39 8.3 28.0 1 6.9 19.4 1.5 1 1 0 1 1 1 0 Myosin tail Fib_alpha PF08702.5 KEZ44787.1 - 0.44 10.6 22.1 0.04 14.0 7.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.1 KEZ44787.1 - 0.55 9.6 25.7 0.25 10.7 12.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Rab5-bind PF09311.6 KEZ44787.1 - 0.57 10.0 31.9 0.25 11.2 12.5 2.4 1 1 1 2 2 2 0 Rabaptin-like protein GAS PF13851.1 KEZ44787.1 - 0.66 9.1 28.6 1.2 8.2 13.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FUSC PF04632.7 KEZ44787.1 - 0.68 8.2 8.3 1.2 7.4 5.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.3 KEZ44787.1 - 2 8.3 33.3 1.3 8.9 5.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 KEZ44787.1 - 2 7.8 28.1 0.87 8.9 8.1 2.2 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 KEZ44787.1 - 2.6 6.4 22.5 0.38 9.1 6.7 2.1 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 KEZ44787.1 - 2.6 6.9 28.5 0.98 8.4 15.9 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-Q PF13094.1 KEZ44787.1 - 2.8 7.9 34.6 1.7 8.6 7.9 3.3 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit MbeD_MobD PF04899.7 KEZ44787.1 - 3.1 7.7 17.3 7.2 6.5 0.4 3.8 2 1 2 4 4 3 0 MbeD/MobD like Allexi_40kDa PF05549.6 KEZ44787.1 - 3.3 6.9 16.6 6.3 6.0 2.4 2.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4047 PF13256.1 KEZ44787.1 - 3.9 7.4 8.0 4.7 7.1 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Atg14 PF10186.4 KEZ44787.1 - 4.2 6.2 29.4 0.079 11.8 10.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KEZ44787.1 - 4.3 6.9 26.4 0.49 9.9 5.3 4.1 1 1 3 4 4 4 0 Septum formation initiator DUF4200 PF13863.1 KEZ44787.1 - 5.5 6.9 27.0 12 5.8 13.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF2968 PF11180.3 KEZ44787.1 - 7 5.9 32.6 2.5 7.4 7.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Mnd1 PF03962.10 KEZ44787.1 - 7 6.2 27.6 1.9 8.1 4.8 2.4 1 1 1 2 2 2 0 Mnd1 family LsmAD PF06741.8 KEZ44788.1 - 7e-21 74.1 2.0 7e-21 74.1 1.4 2.2 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.15 KEZ44789.1 - 9.5e-21 74.1 0.1 1.9e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KEZ44789.1 - 9e-15 54.8 0.1 2.1e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain BMC PF00936.14 KEZ44789.1 - 0.0048 16.5 2.2 0.0057 16.2 0.4 2.1 2 0 0 2 2 2 1 BMC domain LPP20 PF02169.11 KEZ44789.1 - 2.8 8.0 8.3 3.8 7.6 2.0 2.7 2 0 0 2 2 2 0 LPP20 lipoprotein RNA_pol_Rpc82 PF05645.8 KEZ44790.1 - 4.9e-40 137.6 0.0 8.6e-37 127.0 0.0 2.7 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KEZ44790.1 - 3.8e-19 68.3 0.0 7.2e-18 64.2 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KEZ44790.1 - 2.4e-07 30.2 0.1 0.0013 18.1 0.0 3.1 2 0 0 2 2 2 2 TFIIE alpha subunit HTH_IclR PF09339.5 KEZ44790.1 - 3.2e-05 23.4 1.0 0.058 12.9 0.0 3.7 3 0 0 3 3 3 2 IclR helix-turn-helix domain TrmB PF01978.14 KEZ44790.1 - 0.0045 16.6 0.1 8.6 6.1 0.0 4.0 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.2 KEZ44790.1 - 0.0077 15.8 0.3 5 6.8 0.0 3.0 3 0 0 3 3 3 2 MarR family HTH_5 PF01022.15 KEZ44790.1 - 0.012 15.2 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR PF01047.17 KEZ44790.1 - 0.025 14.2 0.0 0.22 11.2 0.0 2.6 3 0 0 3 3 3 0 MarR family HTH_20 PF12840.2 KEZ44790.1 - 0.067 13.0 0.0 15 5.4 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DASH_Spc19 PF08287.6 KEZ44790.1 - 0.091 12.3 1.4 0.42 10.2 1.1 2.0 2 0 0 2 2 2 0 Spc19 Mito_carr PF00153.22 KEZ44791.1 - 5.7e-30 102.8 0.8 1e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Fe_dep_repress PF01325.14 KEZ44792.1 - 0.022 14.6 5.4 0.1 12.5 0.5 3.6 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain IncA PF04156.9 KEZ44792.1 - 1.1 8.8 0.0 1.1 8.8 0.0 8.6 3 1 2 8 8 8 0 IncA protein SKG6 PF08693.5 KEZ44793.1 - 0.0046 16.2 0.0 0.0046 16.2 0.0 2.2 2 1 0 2 2 2 1 Transmembrane alpha-helix domain Sporozoite_P67 PF05642.6 KEZ44793.1 - 0.024 12.5 3.4 0.029 12.2 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF605 PF04652.11 KEZ44793.1 - 0.048 13.0 5.9 0.062 12.6 4.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF1517 PF07466.6 KEZ44793.1 - 0.075 12.0 1.5 0.095 11.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SSP160 PF06933.6 KEZ44793.1 - 0.45 8.4 12.1 0.61 7.9 8.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 KEZ44793.1 - 0.64 8.2 4.1 0.66 8.1 2.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Apt1 PF10351.4 KEZ44793.1 - 1.7 7.3 4.2 2.1 7.1 2.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Period_C PF12114.3 KEZ44793.1 - 2.5 7.6 11.3 3.6 7.1 7.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF515 PF04415.7 KEZ44793.1 - 5.4 5.1 10.7 7.4 4.6 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mannosyl_trans3 PF11051.3 KEZ44794.1 - 3.6e-51 174.1 0.0 5e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative NADH-G_4Fe-4S_3 PF10588.4 KEZ44794.1 - 3.8e-12 45.2 0.5 7.7e-12 44.2 0.2 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DENN PF02141.16 KEZ44795.1 - 6.2e-40 136.8 0.1 1.1e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KEZ44795.1 - 7.4e-06 25.8 0.3 3.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.6 KEZ44795.1 - 0.0021 18.4 3.9 0.0021 18.4 2.7 2.5 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF1900 PF08954.6 KEZ44796.1 - 3.4e-48 162.6 0.0 2.6e-47 159.7 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KEZ44796.1 - 8.8e-34 114.9 0.0 1.9e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KEZ44796.1 - 3.5e-27 93.2 1.2 9e-08 31.7 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat SNARE PF05739.14 KEZ44796.1 - 0.0015 18.1 1.4 0.0026 17.4 0.9 1.3 1 0 0 1 1 1 1 SNARE domain Nucleoporin_N PF08801.6 KEZ44796.1 - 0.021 13.5 0.2 0.23 10.1 0.1 2.4 1 1 2 3 3 3 0 Nup133 N terminal like Apc4_WD40 PF12894.2 KEZ44796.1 - 0.037 13.5 0.0 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KEZ44796.1 - 0.04 12.0 0.8 0.81 7.7 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Apolipoprotein PF01442.13 KEZ44797.1 - 0.024 14.1 0.9 0.065 12.7 0.1 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.6 KEZ44797.1 - 0.049 14.0 1.6 0.37 11.2 0.1 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal zf-C2H2_3 PF13878.1 KEZ44797.1 - 0.093 12.3 0.1 0.29 10.7 0.1 1.8 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Prominin PF05478.6 KEZ44797.1 - 0.12 9.8 0.6 0.18 9.3 0.4 1.2 1 0 0 1 1 1 0 Prominin SSFA2_C PF14723.1 KEZ44797.1 - 0.96 9.1 5.8 1.7 8.3 0.1 3.1 4 0 0 4 4 4 0 Sperm-specific antigen 2 C-terminus CorA PF01544.13 KEZ44797.1 - 1.1 8.2 4.1 1.5 7.7 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Anillin PF08174.6 KEZ44798.1 - 2.7e-31 108.4 0.0 7.5e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KEZ44798.1 - 2.1e-08 34.2 0.0 6.7e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 PH domain DEAD PF00270.24 KEZ44799.1 - 5.9e-45 152.8 1.2 1.1e-44 151.9 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ44799.1 - 1.2e-23 82.7 0.1 2.4e-13 49.7 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ44799.1 - 5.9e-06 26.2 0.0 1.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KEZ44799.1 - 0.032 14.3 0.1 0.093 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.1 KEZ44800.1 - 5.6e-20 71.6 0.0 9.1e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44800.1 - 1e-13 51.5 0.0 1.3e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44800.1 - 1.4e-10 41.5 0.0 2.3e-09 37.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44800.1 - 9.7e-10 38.2 0.0 8.7e-09 35.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44800.1 - 3.6e-08 33.9 0.0 1e-06 29.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44800.1 - 7.4e-05 23.0 0.0 0.00025 21.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44800.1 - 0.00012 21.2 0.0 0.005 15.9 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEZ44800.1 - 0.00075 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KEZ44800.1 - 0.00091 18.3 0.0 0.0028 16.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KEZ44800.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 KEZ44800.1 - 0.012 14.9 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 KEZ44800.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 KEZ44800.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 KEZ44800.1 - 0.09 12.8 0.0 0.41 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KEZ44800.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Catalase PF00199.14 KEZ44801.1 - 4.4e-160 532.5 0.1 5.8e-160 532.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KEZ44801.1 - 3.1e-20 71.8 0.0 5.7e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Nucleoside_tran PF01733.13 KEZ44802.1 - 2.4e-34 118.9 15.9 2.4e-34 118.9 11.0 3.2 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 KEZ44802.1 - 5.2e-09 35.2 32.6 0.0008 18.2 5.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Scs3p PF10261.4 KEZ44802.1 - 0.001 18.1 0.1 0.0056 15.7 0.0 2.1 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4191 PF13829.1 KEZ44802.1 - 0.38 9.8 6.1 1.4 7.9 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) COX14 PF14880.1 KEZ44802.1 - 3 7.5 6.9 0.41 10.3 1.4 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4231 PF14015.1 KEZ44802.1 - 7.1 6.6 7.1 4.3 7.3 1.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Ins_P5_2-kin PF06090.7 KEZ44803.1 - 2.7e-39 135.0 0.0 1.3e-38 132.7 0.0 1.9 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF2404 PF10296.4 KEZ44804.1 - 2.3e-05 24.4 0.0 0.00027 21.0 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) YEATS PF03366.11 KEZ44805.1 - 8.8e-29 99.0 0.4 1.8e-28 98.1 0.3 1.5 1 0 0 1 1 1 1 YEATS family Transglut_i_TM PF14400.1 KEZ44805.1 - 0.28 10.6 2.3 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices NAD_binding_10 PF13460.1 KEZ44806.1 - 0.0016 18.5 0.0 0.02 14.9 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEZ44806.1 - 0.027 13.3 0.0 0.048 12.5 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein Kelch_5 PF13854.1 KEZ44807.1 - 2e-13 49.9 14.2 1.8e-12 46.8 0.2 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 KEZ44807.1 - 2.8e-05 24.0 13.5 0.58 10.4 0.2 5.8 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.10 KEZ44807.1 - 0.002 17.8 1.5 15 5.5 0.0 4.7 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 KEZ44807.1 - 0.0051 16.5 17.9 0.21 11.4 0.3 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Ecl1 PF12855.2 KEZ44808.1 - 6.6e-11 41.3 5.5 1.6e-10 40.1 3.8 1.6 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 KEZ44808.1 - 0.11 11.8 6.2 0.21 10.9 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF581) zf-MYND PF01753.13 KEZ44808.1 - 0.19 11.6 2.7 0.38 10.6 1.9 1.4 1 0 0 1 1 1 0 MYND finger SUZ PF12752.2 KEZ44808.1 - 2.3 8.8 6.8 9.9 6.7 4.7 2.1 1 0 0 1 1 1 0 SUZ domain HAD PF12710.2 KEZ44809.1 - 3.4e-21 76.2 0.1 2.1e-20 73.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEZ44809.1 - 1.3e-20 73.4 0.1 2.4e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ44809.1 - 2.2e-16 60.9 0.8 1.2e-15 58.5 0.5 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ44809.1 - 1.7e-11 43.8 0.0 4.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEZ44809.1 - 0.00088 18.9 0.3 0.0091 15.5 0.1 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEZ44809.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Cript PF10235.4 KEZ44810.1 - 1.1e-10 41.7 0.5 1.1e-10 41.7 0.4 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT Pinin_SDK_memA PF04696.8 KEZ44811.1 - 6.1e-16 58.2 16.4 6.1e-16 58.2 11.4 1.8 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region RGS-like PF09128.6 KEZ44811.1 - 0.062 12.7 4.9 0.58 9.6 0.1 2.3 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain CtIP_N PF10482.4 KEZ44811.1 - 2.5 7.8 15.3 4.4 7.1 9.0 2.3 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF4613 PF15390.1 KEZ44811.1 - 2.7 6.0 6.3 3.8 5.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PHF5 PF03660.9 KEZ44812.1 - 5.6e-52 174.3 10.5 6.4e-52 174.1 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 KEZ44812.1 - 0.49 10.2 15.1 0.16 11.7 5.2 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 KEZ44812.1 - 3.5 7.4 17.3 3 7.6 0.5 3.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 KEZ44812.1 - 4.6 4.7 6.0 4.7 4.7 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 KEZ44812.1 - 7.6 6.3 15.4 0.24 11.1 4.6 2.5 1 1 1 2 2 2 0 PHD-finger Pex26 PF07163.7 KEZ44813.1 - 0.021 13.7 2.1 0.037 12.9 1.4 1.4 1 0 0 1 1 1 0 Pex26 protein COG2 PF06148.6 KEZ44813.1 - 0.032 14.1 1.0 0.059 13.2 0.7 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF572 PF04502.8 KEZ44813.1 - 0.22 10.7 14.1 0.38 9.9 9.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1451 PF07295.6 KEZ44813.1 - 0.53 10.0 8.6 0.97 9.2 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Ycf1 PF05758.7 KEZ44813.1 - 4.6 4.8 8.7 6.9 4.2 6.0 1.2 1 0 0 1 1 1 0 Ycf1 DUF2058 PF09831.4 KEZ44813.1 - 6.1 6.6 14.7 11 5.9 10.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3635 PF12330.3 KEZ44814.1 - 2.4e-05 24.2 0.0 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) DUF1682 PF07946.9 KEZ44815.1 - 4.6e-103 344.4 0.3 5.4e-103 344.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4390 PF14334.1 KEZ44815.1 - 0.076 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) DUF77 PF01910.12 KEZ44816.1 - 5.9e-33 112.3 0.0 7.3e-33 112.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 PI-PLC-X PF00388.14 KEZ44817.1 - 1.2e-62 209.6 0.0 1.8e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KEZ44817.1 - 6e-38 129.4 0.0 1e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KEZ44817.1 - 0.002 18.1 0.0 0.01 15.8 0.0 2.1 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Voltage_CLC PF00654.15 KEZ44818.1 - 2.1e-93 313.1 20.5 2.1e-93 313.1 14.2 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 KEZ44818.1 - 1.5 9.0 10.3 0.036 14.0 1.7 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence NRDE-2 PF08424.5 KEZ44819.1 - 3.1e-74 249.7 0.0 1.2e-73 247.8 0.0 2.0 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KEZ44819.1 - 0.01 16.4 0.4 5.1 8.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Aminotran_3 PF00202.16 KEZ44820.1 - 1.2e-97 326.8 0.0 1.5e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KEZ44820.1 - 0.0035 16.3 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ44820.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase SRI PF08236.6 KEZ44822.1 - 6.4e-25 86.9 6.0 1.3e-24 85.9 4.2 1.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 KEZ44822.1 - 2.1e-22 80.1 0.1 2.1e-22 80.1 0.1 2.9 3 1 0 3 3 3 1 SET domain WW PF00397.21 KEZ44822.1 - 0.00018 21.2 1.7 0.00039 20.2 1.1 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 KEZ44822.1 - 0.00022 20.6 0.2 0.00022 20.6 0.1 2.7 4 0 0 4 4 4 1 TFIIS helical bundle-like domain CAP_N PF01213.14 KEZ44822.1 - 0.016 14.4 9.4 0.46 9.7 2.7 2.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ThiF PF00899.16 KEZ44824.1 - 1.5e-13 50.7 0.2 4.4e-13 49.2 0.0 1.8 2 1 0 2 2 2 1 ThiF family Cut8_N PF14482.1 KEZ44824.1 - 0.32 11.0 2.5 10 6.1 0.3 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Nop14 PF04147.7 KEZ44825.1 - 0.0046 14.9 24.5 0.0065 14.4 17.0 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 KEZ44825.1 - 0.0078 15.5 17.3 0.012 14.8 12.0 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 KEZ44825.1 - 0.011 13.8 18.1 0.024 12.6 12.5 1.5 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KEZ44825.1 - 0.016 14.3 13.2 0.029 13.4 9.1 1.4 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 KEZ44825.1 - 0.082 11.4 2.9 0.14 10.7 2.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.8 KEZ44825.1 - 0.74 8.4 21.5 1.3 7.7 14.9 1.3 1 0 0 1 1 1 0 Paf1 RRN3 PF05327.6 KEZ44825.1 - 1.3 7.0 18.1 2 6.4 12.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 KEZ44825.1 - 1.4 7.2 27.4 0.014 13.8 13.2 1.8 2 0 0 2 2 2 0 Daxx Family Pox_Ag35 PF03286.9 KEZ44825.1 - 1.8 8.0 11.5 4.4 6.7 8.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 KEZ44825.1 - 2.2 8.1 30.1 4.1 7.2 20.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mpp10 PF04006.7 KEZ44825.1 - 6.7 4.9 24.8 11 4.2 17.2 1.3 1 0 0 1 1 1 0 Mpp10 protein eIF-6 PF01912.13 KEZ44826.1 - 8.3e-67 224.1 0.9 4.5e-59 198.8 0.1 2.2 1 1 1 2 2 2 2 eIF-6 family CAF1 PF04857.15 KEZ44827.1 - 9e-69 231.7 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 KEZ44827.1 - 0.046 13.8 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 RFX DNA-binding domain NDUF_B12 PF08122.7 KEZ44828.1 - 6.4e-15 54.6 0.4 9.1e-15 54.1 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CLTH PF10607.4 KEZ44829.1 - 5.2e-29 100.8 0.0 1.1e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain HLH PF00010.21 KEZ44830.1 - 1.4e-12 47.0 0.3 2.9e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 KEZ44830.1 - 0.026 12.8 24.3 0.031 12.5 16.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2235 PF09994.4 KEZ44832.1 - 2.3e-65 220.7 0.0 4e-64 216.6 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KEZ44832.1 - 0.0092 15.7 0.0 0.021 14.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aconitase PF00330.15 KEZ44833.1 - 4.1e-23 81.5 0.0 3.8e-21 75.1 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEZ44833.1 - 2.2e-16 60.1 0.0 3.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain AMP-binding PF00501.23 KEZ44834.1 - 5.9e-67 225.8 0.1 1.8e-66 224.2 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ44834.1 - 1.3e-13 51.6 1.6 1.4e-13 51.5 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 KEZ44834.1 - 0.063 12.3 0.1 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 LysR substrate binding domain DUF4643 PF15485.1 KEZ44836.1 - 0.038 13.4 2.4 0.043 13.2 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) CAF-1_p150 PF11600.3 KEZ44836.1 - 0.05 12.9 0.3 0.059 12.7 0.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EST1 PF10374.4 KEZ44836.1 - 0.094 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Telomerase activating protein Est1 ADH_N PF08240.7 KEZ44837.1 - 8.5e-10 38.3 0.2 3.1e-09 36.5 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEZ44837.1 - 4.3e-08 34.1 0.0 1.3e-07 32.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEZ44837.1 - 0.00064 19.2 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_1 PF00232.13 KEZ44838.1 - 1.9e-156 520.8 0.0 2.3e-156 520.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF4203 PF13886.1 KEZ44839.1 - 2.8e-34 118.4 22.0 3.7e-34 118.0 15.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Erf4 PF10256.4 KEZ44840.1 - 2.7e-28 98.1 0.0 4.5e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PALP PF00291.20 KEZ44840.1 - 0.065 12.4 0.5 4.7 6.3 0.1 2.2 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme STE3 PF02076.10 KEZ44841.1 - 4.2e-35 121.2 14.9 6.5e-35 120.5 10.3 1.3 1 0 0 1 1 1 1 Pheromone A receptor TRAP-gamma PF07074.7 KEZ44841.1 - 0.36 10.3 3.0 30 4.0 0.0 3.3 3 0 0 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SSB PF00436.20 KEZ44842.1 - 1.2e-16 60.3 0.0 1.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family GSH_synth_ATP PF03917.12 KEZ44843.1 - 1.3e-115 385.9 0.0 1.6e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KEZ44843.1 - 6.3e-33 112.9 0.0 1.2e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 KEZ44844.1 - 1.3e-41 142.3 0.0 2.4e-41 141.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ44844.1 - 1.4e-14 53.7 0.2 2.7e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ44844.1 - 0.00083 19.2 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 KEZ44844.1 - 0.34 10.2 0.0 0.68 9.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 DUF4375 PF14300.1 KEZ44844.1 - 0.49 10.3 0.1 1.4 8.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DUF4259 PF14078.1 KEZ44844.1 - 1.4 9.4 5.2 7.5 7.0 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Aminotran_1_2 PF00155.16 KEZ44845.1 - 9.1e-79 265.0 0.0 1.1e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KEZ44845.1 - 3.1e-05 22.8 0.0 6.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KEZ44845.1 - 4.3e-05 21.9 0.0 6.7e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEZ44845.1 - 0.012 14.6 0.2 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.13 KEZ44846.1 - 0.1 12.5 9.1 0.35 10.8 6.3 1.9 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydr_30_2 PF14587.1 KEZ44847.1 - 1.8e-20 73.2 0.1 1.8e-20 73.2 0.1 1.8 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.11 KEZ44847.1 - 4.7e-13 48.1 3.9 4.8e-12 44.8 2.7 2.2 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Rota_NS35 PF02509.9 KEZ44847.1 - 0.24 10.0 0.2 0.37 9.4 0.2 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 HK PF02110.10 KEZ44848.1 - 6.9e-74 248.1 2.6 9.4e-74 247.6 1.8 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KEZ44848.1 - 1.3e-53 180.8 0.3 9.9e-47 158.3 0.0 2.3 1 1 1 2 2 2 2 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KEZ44848.1 - 0.00053 19.3 0.5 0.001 18.4 0.4 1.4 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KEZ44848.1 - 0.013 14.7 0.1 0.025 13.7 0.1 1.5 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Isochorismatase PF00857.15 KEZ44849.1 - 4.7e-26 91.7 0.0 8e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 KEZ44850.1 - 1.8e-17 64.0 0.0 3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ44850.1 - 3.7e-15 56.4 0.0 5.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KEZ44850.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family BP28CT PF08146.7 KEZ44853.1 - 3.2e-37 127.6 2.4 6.4e-37 126.6 0.1 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KEZ44853.1 - 8.3e-20 70.9 5.7 4.2e-19 68.6 0.0 4.8 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KEZ44853.1 - 1.2e-07 31.2 13.1 0.0013 18.5 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 KEZ44853.1 - 9.8e-07 28.9 15.5 0.23 11.7 0.1 6.3 5 1 0 5 5 5 3 HEAT repeats RIX1 PF08167.7 KEZ44853.1 - 0.011 15.3 0.4 0.57 9.8 0.1 3.7 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 KEZ44853.1 - 0.074 13.5 13.3 0.38 11.3 0.1 7.1 6 1 1 7 7 7 0 HEAT-like repeat HABP4_PAI-RBP1 PF04774.10 KEZ44854.1 - 5.3e-06 26.8 6.9 5.3e-06 26.8 4.8 2.8 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family Lin-8 PF03353.10 KEZ44854.1 - 1.3 8.2 6.0 1.8 7.7 4.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MFS_1 PF07690.11 KEZ44855.1 - 4.6e-18 65.0 35.3 1.7e-11 43.4 5.5 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ44855.1 - 1.5e-05 23.6 15.2 0.00011 20.7 4.5 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein DUF1632 PF07857.7 KEZ44855.1 - 0.023 13.9 1.4 0.92 8.7 1.0 2.7 2 0 0 2 2 2 0 CEO family (DUF1632) MFS_1_like PF12832.2 KEZ44855.1 - 0.032 14.0 8.3 0.55 10.0 0.1 3.7 4 0 0 4 4 4 0 MFS_1 like family Actin PF00022.14 KEZ44856.1 - 3.7e-32 111.2 0.0 1.3e-20 73.1 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KEZ44856.1 - 0.0029 16.2 0.0 0.12 10.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF4451 PF14616.1 KEZ44857.1 - 4.9e-35 120.0 0.5 4.9e-35 120.0 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) Iso_dh PF00180.15 KEZ44858.1 - 4.6e-124 413.8 0.0 6.7e-124 413.3 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.24 KEZ44858.1 - 1.7e-08 34.0 6.3 2.7e-08 33.3 4.4 1.3 1 0 0 1 1 1 1 PHD-finger EVE PF01878.13 KEZ44859.1 - 1.6e-49 167.5 0.2 1.6e-49 167.5 0.1 2.0 2 0 0 2 2 2 1 EVE domain RNA_pol_Rbc25 PF08292.7 KEZ44859.1 - 0.073 13.2 0.0 0.073 13.2 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 IER PF05760.7 KEZ44859.1 - 3.3 7.5 14.7 4.4 7.1 10.2 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) SSrecog PF03531.9 KEZ44860.1 - 6e-75 251.3 0.0 1.1e-74 250.5 0.0 1.4 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KEZ44860.1 - 6.6e-25 86.9 0.1 3.6e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 KEZ44860.1 - 0.056 12.6 0.0 0.056 12.6 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain YL1 PF05764.8 KEZ44860.1 - 1.3 8.5 21.0 2.1 7.8 14.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Mg_trans_NIPA PF05653.9 KEZ44861.1 - 9.2e-61 205.4 11.1 2.6e-57 194.0 6.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KEZ44861.1 - 0.00023 21.3 0.7 0.00023 21.3 0.5 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter LRR19-TM PF15176.1 KEZ44861.1 - 0.0026 17.3 0.0 0.0095 15.6 0.0 1.9 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain EamA PF00892.15 KEZ44861.1 - 0.0062 16.5 0.8 0.0062 16.5 0.6 4.0 3 1 1 4 4 4 2 EamA-like transporter family Cytochrom_B_N PF00033.14 KEZ44861.1 - 1.4 8.2 8.0 3.4 6.9 0.0 3.1 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Shisa PF13908.1 KEZ44861.1 - 1.6 8.8 0.0 1.6 8.8 0.0 3.0 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator CD20 PF04103.10 KEZ44861.1 - 7 6.5 13.7 2.1 8.2 0.3 3.4 4 0 0 4 4 4 0 CD20-like family Cnd3 PF12719.2 KEZ44862.1 - 6.8e-94 314.1 1.2 6.8e-94 314.1 0.8 2.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KEZ44862.1 - 2.6e-11 43.6 17.3 4.1e-06 26.9 0.5 5.8 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.17 KEZ44862.1 - 1.5e-07 30.9 11.5 0.22 11.6 0.0 7.3 7 0 0 7 7 7 3 HEAT repeat MMS19_N PF14500.1 KEZ44862.1 - 0.0034 16.6 0.2 0.17 11.1 0.0 3.1 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 KEZ44862.1 - 0.041 13.9 0.5 0.68 10.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 KEZ44862.1 - 0.21 12.1 22.6 0.036 14.5 1.0 7.2 5 1 3 8 8 8 0 HEAT-like repeat Phosphodiest PF01663.17 KEZ44863.1 - 1.4e-15 57.5 0.3 6.2e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEZ44863.1 - 0.00028 20.1 0.0 0.0011 18.2 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KEZ44863.1 - 0.00067 19.1 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2423 PF10338.4 KEZ44864.1 - 6.3e-18 64.4 3.6 6.3e-18 64.4 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) BID PF06393.6 KEZ44864.1 - 0.029 13.7 0.2 0.03 13.6 0.2 1.0 1 0 0 1 1 1 0 BH3 interacting domain (BID) BNIP2 PF12496.3 KEZ44864.1 - 0.03 14.4 1.2 0.035 14.2 0.8 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 P53_C PF11619.3 KEZ44864.1 - 0.031 14.0 0.2 0.066 12.9 0.2 1.5 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain Sigma70_ner PF04546.8 KEZ44864.1 - 0.048 13.2 2.3 0.055 13.0 1.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF515 PF04415.7 KEZ44864.1 - 0.082 11.1 0.6 0.11 10.7 0.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF515) HMG14_17 PF01101.13 KEZ44864.1 - 0.38 11.4 6.0 0.35 11.5 3.3 1.6 1 1 0 1 1 1 0 HMG14 and HMG17 TRAPP PF04051.11 KEZ44865.1 - 5.2e-40 136.4 0.0 5.9e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_C PF02866.13 KEZ44866.1 - 4.2e-45 153.6 0.0 5.8e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 KEZ44866.1 - 2.4e-43 147.3 0.2 3.8e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KEZ44866.1 - 0.0023 16.6 0.0 0.0048 15.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.12 KEZ44867.1 - 3.6e-36 124.0 0.5 4.5e-36 123.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family FA_hydroxylase PF04116.8 KEZ44868.1 - 2.1e-14 53.8 24.8 9.7e-14 51.7 13.9 2.4 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.27 KEZ44869.1 - 4e-72 235.7 11.7 5.7e-11 41.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KEZ44869.1 - 6e-24 84.0 7.5 9.8e-24 83.3 5.2 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KEZ44869.1 - 0.0005 18.3 0.3 0.15 10.1 0.0 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KEZ44869.1 - 0.00058 18.2 0.3 0.07 11.4 0.1 2.9 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KEZ44869.1 - 0.0013 17.5 0.1 0.39 9.4 0.1 3.3 1 1 2 3 3 3 1 Nup133 N terminal like Filament PF00038.16 KEZ44869.1 - 0.013 14.9 1.2 0.021 14.2 0.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein LXG PF04740.7 KEZ44869.1 - 0.027 14.2 0.2 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily SART-1 PF03343.8 KEZ44870.1 - 0.0042 15.5 1.5 0.0051 15.2 1.1 1.1 1 0 0 1 1 1 1 SART-1 family Aa_trans PF01490.13 KEZ44871.1 - 8.3e-58 195.7 24.8 1.1e-57 195.4 17.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KEZ44871.1 - 1.4e-06 27.1 12.4 1.4e-06 27.1 8.6 2.1 2 0 0 2 2 2 1 Amino acid permease HAD_2 PF13419.1 KEZ44872.1 - 2.6e-29 102.6 0.0 3.1e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ44872.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF3321 PF11968.3 KEZ44873.1 - 7.1e-58 195.8 0.0 8.4e-51 172.6 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KEZ44873.1 - 0.0019 17.9 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF1590 PF07629.6 KEZ44873.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) Ribosomal_L23eN PF03939.8 KEZ44874.1 - 9.9e-19 67.1 13.9 3.5e-18 65.3 9.6 2.0 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KEZ44874.1 - 2.8e-16 59.2 1.2 6.1e-16 58.1 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 KEZ44875.1 - 1.1e-19 69.4 0.3 1.4e-19 69.1 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CorA PF01544.13 KEZ44876.1 - 2.6e-42 144.8 0.1 2.1e-41 141.8 0.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SPC12 PF06645.8 KEZ44877.1 - 3.2e-26 90.9 0.0 4e-26 90.6 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.2 KEZ44878.1 - 2.8e-34 117.0 13.4 3.4e-34 116.7 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KEZ44878.1 - 9.1e-17 60.6 9.6 1.2e-16 60.3 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KEZ44878.1 - 4.7e-07 29.5 11.8 3.1e-06 26.9 8.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEZ44878.1 - 0.0014 18.2 11.6 0.025 14.2 8.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ44878.1 - 0.0035 16.9 9.8 0.46 10.2 7.0 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ44878.1 - 0.049 13.6 12.5 0.053 13.5 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 KEZ44878.1 - 0.51 10.5 10.5 39 4.4 7.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 KEZ44878.1 - 0.54 10.0 11.8 5.3 6.8 8.2 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 KEZ44878.1 - 1.2 9.1 10.0 3.7 7.5 6.9 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 KEZ44878.1 - 1.6 8.7 10.5 4.4 7.3 6.5 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KEZ44878.1 - 1.8 8.3 7.0 4.1 7.2 2.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Tyr-DNA_phospho PF06087.7 KEZ44879.1 - 1.4e-36 126.1 0.0 2.6e-13 49.3 0.0 3.4 2 1 1 3 3 3 3 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 KEZ44879.1 - 0.00017 20.8 0.1 0.0004 19.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif CDP-OH_P_transf PF01066.16 KEZ44880.1 - 4.7e-17 62.1 4.4 4.7e-17 62.1 3.0 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 KEZ44881.1 - 3.9e-151 503.3 0.0 5.6e-151 502.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Sec1 PF00995.18 KEZ44881.1 - 3.5e-144 481.5 0.1 4.7e-144 481.1 0.1 1.1 1 0 0 1 1 1 1 Sec1 family GIDA_assoc_3 PF13932.1 KEZ44881.1 - 7.5e-18 64.3 0.1 2.7e-17 62.5 0.1 2.0 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KEZ44881.1 - 8.7e-08 32.2 0.2 3.1e-07 30.4 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ44881.1 - 2.8e-06 26.7 0.2 4.6e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KEZ44881.1 - 0.0017 17.2 1.1 0.42 9.4 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ44881.1 - 0.0088 14.9 6.7 0.021 13.7 4.0 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KEZ44881.1 - 0.058 13.8 0.4 0.2 12.0 0.2 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ44881.1 - 7.3 4.9 8.7 0.14 10.5 0.6 2.2 4 0 0 4 4 4 0 HI0933-like protein Synaptobrevin PF00957.16 KEZ44882.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Synaptobrevin MBOAT PF03062.14 KEZ44883.1 - 1.1e-47 162.7 2.2 1.1e-47 162.7 1.5 2.6 3 1 1 4 4 4 1 MBOAT, membrane-bound O-acyltransferase family UAA PF08449.6 KEZ44883.1 - 1.7e-11 43.6 15.5 3.1e-11 42.7 10.8 1.4 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KEZ44883.1 - 3.4e-09 36.5 7.8 3.4e-09 36.5 5.4 3.4 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 KEZ44883.1 - 0.00084 19.3 8.6 0.00084 19.3 6.0 4.6 4 0 0 4 4 4 2 EamA-like transporter family ARD PF03079.9 KEZ44884.1 - 7e-34 117.0 0.2 7e-34 117.0 0.1 1.6 2 0 0 2 2 2 1 ARD/ARD' family adh_short PF00106.20 KEZ44884.1 - 9.7e-20 71.1 0.0 1.7e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ44884.1 - 4.8e-11 42.6 0.0 1.2e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ44884.1 - 3e-08 33.3 0.1 8.3e-08 31.9 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Cupin_2 PF07883.6 KEZ44884.1 - 1.6e-07 30.7 0.1 3.7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KEZ44884.1 - 1.2e-05 25.0 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain RmlD_sub_bind PF04321.12 KEZ44884.1 - 0.00064 18.7 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KEZ44884.1 - 0.0014 17.3 0.1 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEZ44884.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEZ44884.1 - 0.058 12.6 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 KEZ44884.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Peptidase_M24 PF00557.19 KEZ44885.1 - 5.8e-44 150.1 0.0 8.8e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KEZ44885.1 - 3.7e-20 72.7 0.0 1.2e-17 64.5 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain tRNA-synt_1b PF00579.20 KEZ44887.1 - 2.9e-40 138.2 0.0 3.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Fcf2 PF08698.6 KEZ44888.1 - 5.9e-26 90.3 0.0 1.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Ribosomal_S10 PF00338.17 KEZ44888.1 - 4e-18 65.0 0.0 8e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CBFD_NFYB_HMF PF00808.18 KEZ44889.1 - 1.4e-19 69.9 0.6 2.1e-19 69.3 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KEZ44889.1 - 2.7e-11 43.4 0.1 4.2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KEZ44889.1 - 0.033 13.9 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 KEZ44890.1 - 2.2e-120 401.7 0.7 2.2e-120 401.7 0.5 2.6 3 1 0 3 3 3 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 KEZ44890.1 - 0.0023 17.4 4.2 0.0023 17.4 2.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) COG5 PF10392.4 KEZ44890.1 - 0.17 11.8 8.3 2.5 8.0 3.5 3.3 3 0 0 3 3 3 0 Golgi transport complex subunit 5 RRM_2 PF04059.7 KEZ44891.1 - 2.3e-18 65.9 0.6 3.1e-11 43.1 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif 2 Aldo_ket_red PF00248.16 KEZ44892.1 - 1e-55 188.5 0.0 1.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MerR_1 PF13411.1 KEZ44892.1 - 0.067 12.9 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein Lipase_GDSL_2 PF13472.1 KEZ44893.1 - 0.0015 18.6 0.7 0.15 12.2 0.0 2.1 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family DUF1345 PF07077.6 KEZ44893.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) IBV_3C PF03620.8 KEZ44893.1 - 0.033 14.0 0.3 0.061 13.2 0.0 1.7 2 0 0 2 2 2 0 IBV 3C protein Ank_2 PF12796.2 KEZ44894.1 - 6.2e-36 122.6 0.7 9.8e-17 61.0 0.1 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ44894.1 - 1.7e-31 106.4 3.4 2.7e-07 30.0 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 KEZ44894.1 - 1.9e-24 85.5 1.3 3.8e-09 36.8 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ44894.1 - 1.3e-23 80.7 1.3 2e-05 24.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KEZ44894.1 - 6.2e-23 80.2 2.6 1.8e-06 28.0 0.0 4.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) AAA_16 PF13191.1 KEZ44895.1 - 5e-06 26.6 0.0 9.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KEZ44895.1 - 5.1e-06 26.2 0.2 6.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ44895.1 - 0.00013 22.0 0.0 0.00036 20.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ44895.1 - 0.00034 20.3 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 KEZ44895.1 - 0.0012 17.7 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 KEZ44895.1 - 0.0024 18.0 0.1 0.0044 17.1 0.1 1.4 1 0 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.13 KEZ44895.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KEZ44895.1 - 0.02 15.1 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KEZ44895.1 - 0.023 15.0 0.1 0.041 14.1 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.6 KEZ44895.1 - 0.024 14.5 0.1 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 KEZ44895.1 - 0.026 14.4 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEZ44895.1 - 0.028 13.8 0.1 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KEZ44895.1 - 0.032 14.1 0.2 0.056 13.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEZ44895.1 - 0.035 13.5 0.3 0.053 12.9 0.2 1.2 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 KEZ44895.1 - 0.051 13.2 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KEZ44895.1 - 0.067 14.0 0.3 0.16 12.7 0.1 1.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEZ44895.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEZ44895.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1029 PF06269.7 KEZ44897.1 - 0.2 11.6 5.7 1 9.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1029) Claudin_2 PF13903.1 KEZ44899.1 - 0.0073 16.0 0.2 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Hint_2 PF13403.1 KEZ44899.1 - 0.025 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Hint domain DUF3040 PF11239.3 KEZ44899.1 - 3.2 7.8 4.9 1.3 9.1 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ABC2_membrane PF01061.19 KEZ44900.1 - 1.8e-89 298.4 48.4 8.9e-49 165.4 9.3 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEZ44900.1 - 9.5e-39 132.8 0.0 9.2e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEZ44900.1 - 1.8e-25 88.5 0.2 5.4e-22 77.4 0.0 3.0 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KEZ44900.1 - 6e-11 41.9 33.8 9.7e-07 28.1 7.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KEZ44900.1 - 2.2e-05 23.9 0.0 0.0035 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEZ44900.1 - 0.00022 20.4 0.1 0.016 14.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ44900.1 - 0.00026 21.1 0.0 0.16 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.1 KEZ44900.1 - 0.0015 18.5 0.0 0.0038 17.2 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 KEZ44900.1 - 0.0019 18.1 0.1 0.38 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KEZ44900.1 - 0.0024 18.6 0.0 0.73 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KEZ44900.1 - 0.0034 17.3 0.1 0.28 11.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ44900.1 - 0.0046 16.4 0.2 0.078 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 KEZ44900.1 - 0.013 14.9 0.3 0.35 10.3 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KEZ44900.1 - 0.016 15.2 0.0 3.7 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KEZ44900.1 - 0.017 15.3 0.0 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEZ44900.1 - 0.019 14.0 0.1 0.64 9.0 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEZ44900.1 - 0.023 14.4 0.1 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 KEZ44900.1 - 0.025 14.0 1.0 1.1 8.7 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KEZ44900.1 - 0.11 12.9 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 KEZ44900.1 - 0.11 12.4 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 KEZ44900.1 - 0.12 12.1 0.2 1 9.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KEZ44900.1 - 0.15 12.0 0.0 33 4.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KEZ44900.1 - 0.19 11.3 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KEZ44900.1 - 0.24 11.0 0.8 4 7.0 0.4 2.3 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 KEZ44900.1 - 0.27 10.8 0.8 2.9 7.5 0.2 2.5 2 1 1 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 KEZ44900.1 - 0.34 9.8 0.0 18 4.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 KEZ44901.1 - 1.3e-20 73.6 0.0 1.5e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44901.1 - 2.8e-15 56.1 0.0 3.6e-14 52.4 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ44901.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MaoC_dehydrat_N PF13452.1 KEZ44902.1 - 3.2e-05 23.7 0.0 0.00049 19.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.14 KEZ44902.1 - 0.005 16.2 1.2 0.0082 15.5 0.0 1.9 3 0 0 3 3 3 1 MaoC like domain Fungal_trans PF04082.13 KEZ44903.1 - 7.7e-15 54.4 0.0 4.7e-12 45.3 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 KEZ44905.1 - 1.9e-72 243.8 0.0 8.1e-72 241.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ44905.1 - 7.7e-51 172.7 0.1 3.2e-50 170.7 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ44905.1 - 2.5e-20 72.1 0.1 5.5e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Aldolase_II PF00596.16 KEZ44906.1 - 1.1e-42 145.6 0.0 1.5e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Oxidored_FMN PF00724.15 KEZ44909.1 - 3.3e-68 230.1 0.0 4e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AMP-binding PF00501.23 KEZ44912.1 - 4.1e-51 173.6 0.0 5.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 KEZ44913.1 - 8.9e-17 60.8 0.2 2.8e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 KEZ44914.1 - 2.6e-23 82.5 0.0 4.2e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44914.1 - 1.2e-13 51.2 0.0 2.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44914.1 - 1.4e-10 41.5 0.0 1.6e-09 38.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44914.1 - 2.8e-10 39.9 0.0 5.2e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44914.1 - 4.4e-08 33.6 0.0 1.4e-06 28.8 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44914.1 - 9.5e-06 25.9 0.0 4.8e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44914.1 - 1.7e-05 24.0 0.0 0.00053 19.1 0.0 2.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ44914.1 - 0.0017 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEZ44914.1 - 0.0027 16.8 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KEZ44914.1 - 0.0071 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KEZ44914.1 - 0.008 15.2 0.0 0.022 13.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ44914.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KEZ44914.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MARVEL PF01284.18 KEZ44915.1 - 0.42 10.4 8.8 1.8 8.3 6.1 2.0 1 1 0 1 1 1 0 Membrane-associating domain Methyltransf_23 PF13489.1 KEZ44916.1 - 2.6e-19 69.5 0.0 4.5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44916.1 - 5.9e-12 46.1 0.0 1.2e-10 41.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44916.1 - 1.8e-11 43.8 0.0 2e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44916.1 - 1.7e-09 37.9 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44916.1 - 1.2e-06 28.7 0.0 4e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44916.1 - 2.4e-06 27.9 0.0 1.8e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ44916.1 - 0.00078 18.5 0.0 0.002 17.2 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ44916.1 - 0.0018 17.6 0.0 0.0098 15.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KEZ44916.1 - 0.0019 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ44916.1 - 0.0071 16.3 0.0 0.026 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ44916.1 - 0.0088 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KEZ44916.1 - 0.032 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 KEZ44916.1 - 0.044 12.9 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CheR PF01739.13 KEZ44916.1 - 0.049 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 KEZ44916.1 - 0.1 11.7 0.0 0.27 10.3 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KEZ44917.1 - 2.1e-14 53.5 0.0 4.1e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44917.1 - 3.5e-13 50.0 0.0 2.8e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44917.1 - 3.7e-11 42.8 0.0 1.6e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44917.1 - 3.8e-07 30.4 0.0 7.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44917.1 - 2.2e-06 28.0 0.0 1.5e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ44917.1 - 0.0023 17.3 0.0 0.0061 15.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ44917.1 - 0.0024 17.8 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44917.1 - 0.0089 15.1 0.0 0.65 9.0 0.0 2.8 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ44917.1 - 0.0089 16.3 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ44917.1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KEZ44917.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KEZ44917.1 - 0.035 13.1 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.10 KEZ44917.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HET PF06985.6 KEZ44919.1 - 3e-35 121.3 0.1 6.6e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.8 KEZ44919.1 - 7.5e-29 100.6 0.0 1.2e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ44919.1 - 9.3e-19 68.1 0.0 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEZ44919.1 - 5.4e-05 22.7 0.0 0.00017 21.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KEZ44919.1 - 0.00011 22.2 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KEZ44919.1 - 0.1 11.2 0.0 0.22 10.2 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEZ44920.1 - 7.7e-18 64.9 0.4 1.8e-17 63.7 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ44920.1 - 5.2e-09 36.0 0.7 7.2e-09 35.5 0.1 1.4 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KEZ44920.1 - 0.00063 19.5 0.1 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KEZ44920.1 - 0.13 12.0 0.1 0.29 10.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KEZ44921.1 - 8.7e-36 123.8 0.1 1.1e-35 123.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ44921.1 - 2.2e-29 102.5 0.5 3.1e-29 102.0 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ44921.1 - 2.7e-09 36.9 0.2 4.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ44921.1 - 7.9e-05 22.1 0.2 0.00019 20.9 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEZ44921.1 - 0.0061 16.5 0.2 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KEZ44921.1 - 0.037 13.6 0.2 0.056 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 KEZ44922.1 - 1.3e-16 60.2 0.1 3.4e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KEZ44923.1 - 3.1e-77 260.0 22.6 3.6e-77 259.8 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ44923.1 - 2.5e-25 88.9 51.4 3.4e-19 68.7 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 KEZ44923.1 - 0.0027 16.6 5.4 0.0027 16.6 3.7 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein HD_4 PF13328.1 KEZ44923.1 - 0.033 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 HD domain Aldedh PF00171.17 KEZ44924.1 - 1.4e-127 425.8 0.0 4.6e-116 387.8 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family SNF2_N PF00176.18 KEZ44925.1 - 1.9e-37 128.6 0.1 2.5e-35 121.7 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ44925.1 - 3.9e-09 36.2 0.0 8.7e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ44925.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_34 PF13872.1 KEZ44925.1 - 0.17 10.6 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 NACHT PF05729.7 KEZ44926.1 - 2.8e-10 40.0 0.0 5.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 KEZ44926.1 - 3.2e-06 27.3 0.0 9.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ44926.1 - 4.4e-05 23.5 0.5 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 KEZ44926.1 - 5.1e-05 22.9 0.0 0.00015 21.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KEZ44926.1 - 0.00015 21.9 0.0 0.00044 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KEZ44926.1 - 0.00053 19.0 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KEZ44926.1 - 0.0024 17.7 0.0 0.0071 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ44926.1 - 0.0076 15.9 0.1 0.028 14.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KEZ44926.1 - 0.0096 15.3 0.6 4.8 6.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 KEZ44926.1 - 0.012 15.0 0.0 0.12 11.7 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KEZ44926.1 - 0.022 13.6 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 KEZ44926.1 - 0.031 13.3 0.0 0.11 11.5 0.0 2.0 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 KEZ44926.1 - 0.033 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cellulase PF00150.13 KEZ44927.1 - 2.5e-13 49.9 0.0 1.8e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 KEZ44927.1 - 4.4e-07 29.0 0.0 4.1e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KEZ44927.1 - 0.00015 20.9 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Cellulase-like PF12876.2 KEZ44927.1 - 0.0066 16.8 0.0 0.022 15.2 0.0 1.9 1 0 0 1 1 1 1 Sugar-binding cellulase-like Nab1 PF04902.7 KEZ44929.1 - 0.00035 20.1 3.5 0.0051 16.3 0.5 2.3 2 0 0 2 2 2 2 Conserved region in Nab1 DUF1785 PF08699.5 KEZ44929.1 - 0.02 14.2 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1785) MalF_P2 PF14785.1 KEZ44929.1 - 0.2 11.5 1.9 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain DUF842 PF05811.8 KEZ44929.1 - 0.25 10.7 12.4 2.3 7.6 3.7 3.5 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Syntaxin-6_N PF09177.6 KEZ44929.1 - 0.94 9.9 5.6 1.1 9.7 0.3 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Abhydrolase_6 PF12697.2 KEZ44930.1 - 6.1e-22 78.6 2.0 1.4e-21 77.4 1.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ44930.1 - 9.6e-13 48.1 0.0 3.2e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ44930.1 - 3.5e-11 43.0 0.0 1.4e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEZ44930.1 - 3.1e-08 33.3 0.0 8.1e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KEZ44930.1 - 0.0078 15.5 0.0 0.025 13.8 0.0 1.8 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KEZ44930.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold AATase PF07247.7 KEZ44931.1 - 0.029 12.9 0.0 0.13 10.7 0.0 1.8 1 1 0 1 1 1 0 Alcohol acetyltransferase Phage_holin_1 PF04531.8 KEZ44931.1 - 0.056 13.5 0.7 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin ImpA-rel_N PF06812.7 KEZ44931.1 - 0.057 13.1 2.4 0.086 12.6 0.4 2.2 2 0 0 2 2 2 0 ImpA-related N-terminal Fungal_trans PF04082.13 KEZ44932.1 - 6.1e-12 44.9 0.5 1e-11 44.2 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dynamin_N PF00350.18 KEZ44934.1 - 4.1e-26 91.7 0.0 1.2e-25 90.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEZ44934.1 - 1.2e-12 47.2 0.0 6.4e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KEZ44934.1 - 0.00071 19.5 0.0 0.0053 16.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ44934.1 - 0.0013 19.1 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_21 PF13304.1 KEZ44934.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEZ44934.1 - 0.041 13.8 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Methyltransf_23 PF13489.1 KEZ44935.1 - 6.6e-18 64.9 0.0 9.5e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44935.1 - 5.6e-11 42.7 0.0 1.9e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44935.1 - 2.5e-10 40.1 0.0 3.6e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44935.1 - 8e-10 39.2 0.0 2.8e-08 34.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44935.1 - 3.1e-09 37.2 0.0 1.4e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ44935.1 - 2.5e-07 30.9 0.0 7.3e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44935.1 - 4.1e-06 26.0 0.0 9.6e-05 21.5 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEZ44935.1 - 7.8e-05 21.7 0.0 0.00029 19.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ44935.1 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KEZ44935.1 - 0.00028 20.9 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ44935.1 - 0.0021 18.0 0.0 0.015 15.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ44935.1 - 0.0094 15.0 0.0 0.017 14.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KEZ44935.1 - 0.039 13.0 0.0 0.078 12.0 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 KEZ44935.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase HET PF06985.6 KEZ44936.1 - 1.6e-33 115.8 0.0 5.3e-33 114.1 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3050 PF11251.3 KEZ44937.1 - 0.063 12.5 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Glyco_hydro_7 PF00840.15 KEZ44939.1 - 1.4e-82 277.4 21.5 5e-47 160.2 7.4 5.1 1 1 2 3 3 3 3 Glycosyl hydrolase family 7 AAA_22 PF13401.1 KEZ44939.1 - 0.00024 21.2 0.0 0.00092 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ44939.1 - 0.0039 17.2 0.1 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 KEZ44939.1 - 0.0089 16.3 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 KEZ44939.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KEZ44939.1 - 0.025 14.7 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 KEZ44939.1 - 0.028 15.2 0.1 0.23 12.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 KEZ44939.1 - 0.038 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KEZ44939.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEZ44939.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Viral_helicase1 PF01443.13 KEZ44939.1 - 0.19 11.2 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Striatin PF08232.7 KEZ44940.1 - 0.00074 19.8 3.1 0.0011 19.3 2.1 1.2 1 0 0 1 1 1 1 Striatin family DUF724 PF05266.9 KEZ44940.1 - 0.0026 17.4 0.9 0.004 16.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 KEZ44940.1 - 0.0028 17.5 0.2 0.0055 16.5 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 KEZ44940.1 - 0.0056 15.8 1.9 0.0081 15.2 1.3 1.2 1 0 0 1 1 1 1 Tropomyosin bZIP_2 PF07716.10 KEZ44940.1 - 0.0061 16.3 10.2 0.013 15.3 7.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_UL25 PF01499.11 KEZ44940.1 - 0.086 11.1 1.8 0.096 10.9 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family TMF_DNA_bd PF12329.3 KEZ44940.1 - 0.093 12.5 0.8 0.17 11.7 0.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ParcG PF10274.4 KEZ44940.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Parkin co-regulated protein bZIP_1 PF00170.16 KEZ44940.1 - 0.17 11.8 8.8 1.6 8.7 6.1 2.2 1 1 0 1 1 1 0 bZIP transcription factor IncA PF04156.9 KEZ44940.1 - 0.91 9.0 4.3 1.4 8.4 3.0 1.2 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 KEZ44945.1 - 5e-20 71.5 17.7 1.2e-18 66.9 13.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ44946.1 - 4.3e-11 42.1 0.1 6.9e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ44946.1 - 8.1e-05 22.4 13.9 0.0001 22.1 6.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KEZ44947.1 - 3.6e-85 286.2 25.5 4.4e-85 285.9 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ44947.1 - 5.5e-24 84.5 29.0 5.5e-24 84.5 20.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ44947.1 - 2.8e-05 22.7 8.2 2.8e-05 22.7 5.7 3.6 2 2 2 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 KEZ44947.1 - 0.0021 17.8 0.5 0.0021 17.8 0.4 3.2 3 0 0 3 3 3 1 MFS_1 like family Glyco_hydro_3 PF00933.16 KEZ44948.1 - 1.6e-77 260.4 0.0 2.3e-77 259.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ44948.1 - 2.4e-55 187.5 0.0 8.4e-55 185.7 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ44948.1 - 1e-17 63.8 0.0 3.2e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KEZ44948.1 - 0.0063 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Diphtheria_C PF02763.9 KEZ44948.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Diphtheria toxin, C domain F-box-like PF12937.2 KEZ44949.1 - 8.9e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KEZ44949.1 - 0.0044 16.6 0.1 0.0098 15.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain HI0933_like PF03486.9 KEZ44950.1 - 0.32 9.4 0.8 0.77 8.1 0.6 1.5 2 0 0 2 2 2 0 HI0933-like protein Aa_trans PF01490.13 KEZ44951.1 - 8.6e-36 123.2 31.2 9.8e-36 123.0 21.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cation_ATPase_C PF00689.16 KEZ44951.1 - 0.51 9.8 21.3 0.02 14.4 3.3 2.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus 7tm_7 PF08395.7 KEZ44951.1 - 1 8.3 21.4 0.014 14.4 1.0 3.4 2 1 0 3 3 3 0 7tm Chemosensory receptor Aldedh PF00171.17 KEZ44952.1 - 1.5e-131 438.9 0.2 1.7e-131 438.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3879 PF12995.2 KEZ44952.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) FMN_dh PF01070.13 KEZ44953.1 - 2.5e-115 385.1 0.0 3.1e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KEZ44953.1 - 1.6e-05 23.9 0.5 2.9e-05 23.1 0.3 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KEZ44953.1 - 0.00039 19.4 0.1 0.00084 18.3 0.0 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KEZ44953.1 - 0.00051 19.3 0.1 0.011 15.0 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 KEZ44953.1 - 0.0037 16.4 0.7 0.0055 15.8 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 KEZ44953.1 - 0.01 14.7 0.1 0.023 13.6 0.1 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.12 KEZ44953.1 - 0.014 14.5 0.0 0.62 9.1 0.0 2.9 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI ThiG PF05690.9 KEZ44953.1 - 0.064 12.3 0.1 0.51 9.3 0.0 2.1 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Dus PF01207.12 KEZ44953.1 - 0.1 11.4 0.0 1.4 7.7 0.0 2.4 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) Fungal_trans_2 PF11951.3 KEZ44954.1 - 7.2e-46 156.5 0.3 9.7e-46 156.0 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 KEZ44955.1 - 4.6e-95 318.3 0.0 6.5e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Epimerase PF01370.16 KEZ44955.1 - 1.1e-05 25.0 0.0 0.13 11.6 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEZ44955.1 - 2.8e-05 23.4 0.0 6.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KEZ44955.1 - 0.0023 16.9 0.0 0.0044 15.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KEZ44955.1 - 0.057 13.7 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Aldedh PF00171.17 KEZ44956.1 - 1.2e-160 534.8 0.1 2e-160 534.1 0.1 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family APH PF01636.18 KEZ44956.1 - 1.6e-11 44.3 0.0 7.8e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family LuxC PF05893.9 KEZ44956.1 - 2.8e-06 26.2 0.0 4.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KEZ44956.1 - 0.016 14.4 0.0 0.085 12.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Choline_kinase PF01633.15 KEZ44956.1 - 0.03 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop14 PF04147.7 KEZ44958.1 - 0.0011 17.0 8.8 0.0014 16.7 6.1 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 KEZ44958.1 - 0.0018 16.8 14.7 0.0026 16.3 10.2 1.1 1 0 0 1 1 1 1 Daxx Family TFIIF_alpha PF05793.7 KEZ44958.1 - 0.0029 16.0 8.2 0.004 15.5 5.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PRP21_like_P PF12230.3 KEZ44958.1 - 0.011 15.2 9.2 0.017 14.6 6.4 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Pox_Ag35 PF03286.9 KEZ44958.1 - 0.014 14.8 5.5 0.022 14.2 3.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Dicty_REP PF05086.7 KEZ44958.1 - 0.029 12.1 3.9 0.038 11.7 2.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 KEZ44958.1 - 0.087 10.6 7.3 0.12 10.2 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSP_II PF05432.6 KEZ44958.1 - 0.094 11.9 16.6 0.15 11.3 11.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SMN PF06003.7 KEZ44958.1 - 0.1 11.6 4.3 0.15 11.1 3.0 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) FAM176 PF14851.1 KEZ44958.1 - 0.11 12.1 4.8 0.19 11.3 3.3 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 KEZ44958.1 - 0.14 11.7 11.6 0.23 11.0 8.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region VID27 PF08553.5 KEZ44958.1 - 0.23 9.6 10.2 0.31 9.2 7.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ycf1 PF05758.7 KEZ44958.1 - 0.24 9.0 3.7 0.31 8.7 2.6 1.1 1 0 0 1 1 1 0 Ycf1 TLP-20 PF06088.6 KEZ44958.1 - 0.36 10.4 5.0 0.69 9.5 3.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DDHD PF02862.12 KEZ44958.1 - 0.46 10.2 3.9 0.65 9.7 2.7 1.2 1 0 0 1 1 1 0 DDHD domain SDA1 PF05285.7 KEZ44958.1 - 0.52 9.5 14.0 0.76 8.9 9.7 1.1 1 0 0 1 1 1 0 SDA1 Prothymosin PF03247.9 KEZ44958.1 - 0.58 10.3 29.6 1 9.5 20.5 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family RNA_pol_3_Rpc31 PF11705.3 KEZ44958.1 - 0.83 9.5 13.6 1.3 8.9 9.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 KEZ44958.1 - 0.93 7.4 11.3 1.5 6.7 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 KEZ44958.1 - 1.1 9.1 10.7 1.6 8.5 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.1 KEZ44958.1 - 1.4 9.2 11.8 2.6 8.4 8.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 KEZ44958.1 - 1.5 8.1 13.6 2.2 7.5 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 KEZ44958.1 - 1.7 7.1 7.1 2.5 6.5 5.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.8 KEZ44958.1 - 1.8 7.2 18.4 3.7 6.1 12.8 1.5 1 0 0 1 1 1 0 Paf1 DUF2890 PF11081.3 KEZ44958.1 - 2 8.4 17.5 3.5 7.6 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TRAP_alpha PF03896.11 KEZ44958.1 - 2.2 7.1 9.8 3.3 6.6 6.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.7 KEZ44958.1 - 4.5 6.3 17.9 7.8 5.5 12.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 KEZ44958.1 - 5.3 6.2 10.1 11 5.2 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3381 PF11861.3 KEZ44958.1 - 6.1 6.3 16.6 9.5 5.6 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RNA_pol_Rpc4 PF05132.9 KEZ44958.1 - 6.4 6.7 9.3 12 5.9 6.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 eIF-3c_N PF05470.7 KEZ44958.1 - 6.6 4.6 11.2 12 3.8 7.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YqfQ PF14181.1 KEZ44958.1 - 7.1 6.6 11.4 27 4.7 8.1 1.8 2 0 0 2 2 1 0 YqfQ-like protein Pox_RNA_Pol_19 PF05320.7 KEZ44958.1 - 8 6.1 13.3 14 5.4 9.2 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Pkinase PF00069.20 KEZ44960.1 - 2.9e-20 72.5 0.0 4.3e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ44960.1 - 9e-14 51.1 0.0 2.8e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Methyltransf_23 PF13489.1 KEZ44961.1 - 1.1e-22 80.4 0.0 2e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44961.1 - 3e-12 46.8 0.0 8.8e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44961.1 - 2.4e-10 40.9 0.0 1.5e-09 38.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44961.1 - 2.9e-10 39.9 0.0 1.9e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44961.1 - 1.9e-09 37.9 0.0 7.3e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44961.1 - 5.3e-08 32.2 0.0 5e-06 25.8 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ44961.1 - 2.9e-07 30.7 0.0 7.6e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ44961.1 - 1.5e-05 25.0 0.0 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KEZ44961.1 - 6.6e-05 22.0 0.0 0.00018 20.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ44961.1 - 0.00032 20.1 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ44961.1 - 0.00038 20.4 0.0 0.0022 17.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEZ44961.1 - 0.00063 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FmrO PF07091.6 KEZ44961.1 - 0.0065 15.4 0.0 0.013 14.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_PK PF05891.7 KEZ44961.1 - 0.013 14.8 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 KEZ44961.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 KEZ44961.1 - 0.047 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PALP PF00291.20 KEZ44962.1 - 5.7e-55 186.6 0.1 9.5e-55 185.9 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 KEZ44962.1 - 1.3e-30 106.3 0.3 2.8e-30 105.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEZ44962.1 - 9.8e-17 60.7 0.0 2.1e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEZ44962.1 - 3.1e-05 23.7 0.1 5.8e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 KEZ44962.1 - 0.094 11.4 1.3 2.3 6.8 0.1 2.7 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase UPF0253 PF06786.7 KEZ44963.1 - 0.074 13.1 0.0 3.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) ABC_membrane PF00664.18 KEZ44964.1 - 2.4e-78 263.3 32.6 9.6e-47 159.6 5.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ44964.1 - 5.7e-63 211.2 0.0 9.5e-31 106.9 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ44964.1 - 2.3e-16 59.7 0.7 3.2e-08 33.0 0.1 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ44964.1 - 2.5e-11 44.1 0.0 0.042 13.8 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.1 KEZ44964.1 - 8.5e-10 38.9 0.0 0.0012 18.8 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KEZ44964.1 - 1.4e-09 37.3 0.1 5e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KEZ44964.1 - 1.7e-08 34.6 0.3 0.028 14.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KEZ44964.1 - 1.7e-08 35.2 0.0 0.01 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEZ44964.1 - 1.5e-07 30.7 0.0 0.019 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KEZ44964.1 - 2e-07 29.9 0.2 0.0033 16.0 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_10 PF12846.2 KEZ44964.1 - 1.9e-06 27.5 0.3 0.024 14.0 0.0 4.2 5 0 0 5 5 4 1 AAA-like domain AAA_23 PF13476.1 KEZ44964.1 - 2.5e-06 27.9 0.2 0.094 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KEZ44964.1 - 2.9e-06 27.6 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KEZ44964.1 - 5.4e-06 26.6 1.0 1.7 8.8 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEZ44964.1 - 1.7e-05 24.4 0.3 1 9.1 0.0 3.9 3 0 0 3 3 3 2 Part of AAA domain DUF3987 PF13148.1 KEZ44964.1 - 3.8e-05 22.4 0.1 0.00052 18.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Rad17 PF03215.10 KEZ44964.1 - 4.7e-05 22.2 0.0 0.11 11.1 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 KEZ44964.1 - 0.00012 21.5 1.0 0.62 9.4 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 KEZ44964.1 - 0.00012 22.0 0.0 0.73 9.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 KEZ44964.1 - 0.0002 21.2 8.7 0.029 14.2 0.2 4.1 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 KEZ44964.1 - 0.00024 20.6 2.2 1.1 8.7 0.0 3.9 5 0 0 5 5 3 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 KEZ44964.1 - 0.00044 20.1 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KEZ44964.1 - 0.00064 19.4 0.1 3.2 7.4 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KEZ44964.1 - 0.00092 18.7 0.0 0.92 8.9 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MobB PF03205.9 KEZ44964.1 - 0.00099 18.8 0.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KEZ44964.1 - 0.0013 18.3 0.1 0.32 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KEZ44964.1 - 0.0018 17.7 0.8 1.1 8.5 0.0 3.6 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_30 PF13604.1 KEZ44964.1 - 0.0022 17.6 6.7 1.7 8.1 0.0 4.4 5 0 0 5 5 4 2 AAA domain ATP_bind_1 PF03029.12 KEZ44964.1 - 0.0058 16.1 0.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 KEZ44964.1 - 0.01 15.7 0.1 9.9 6.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.1 KEZ44964.1 - 0.018 14.1 0.0 0.8 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 KEZ44964.1 - 0.019 14.6 0.3 45 3.6 0.1 3.9 4 0 0 4 4 4 0 NTPase RNA_helicase PF00910.17 KEZ44964.1 - 0.023 14.8 0.0 9.6 6.4 0.0 3.1 3 0 0 3 3 2 0 RNA helicase PRK PF00485.13 KEZ44964.1 - 0.04 13.4 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KEZ44964.1 - 0.077 12.9 0.0 11 5.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 KEZ44964.1 - 0.096 12.3 0.0 14 5.3 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase SRPRB PF09439.5 KEZ44964.1 - 0.097 11.8 0.0 36 3.5 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 KEZ44965.1 - 6.9e-08 32.3 0.0 2.5e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEZ44965.1 - 0.00014 21.9 0.0 0.0094 15.9 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ44965.1 - 0.0004 20.5 0.0 0.0016 18.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEZ44965.1 - 0.019 13.8 0.0 0.29 9.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 KEZ44965.1 - 0.022 14.9 0.1 0.14 12.3 0.0 2.4 3 0 0 3 3 3 0 RNA helicase Suf PF05843.9 KEZ44965.1 - 0.68 9.6 3.7 2 8.0 2.5 1.8 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) SNF2_N PF00176.18 KEZ44966.1 - 3.2e-68 229.7 0.0 4.8e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KEZ44966.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KEZ44966.1 - 0.00047 20.0 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AMP-binding PF00501.23 KEZ44967.1 - 2.7e-87 292.8 0.0 3.3e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ44967.1 - 2.1e-16 60.6 0.0 8e-16 58.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KEZ44968.1 - 2.3e-27 95.6 60.0 2.3e-27 95.6 41.6 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily WBP-1 PF11669.3 KEZ44968.1 - 0.41 10.7 2.2 0.98 9.5 1.6 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF4470 PF14737.1 KEZ44969.1 - 0.00089 18.9 0.1 0.67 9.7 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4470) Methyltransf_23 PF13489.1 KEZ44971.1 - 3.2e-26 91.9 0.0 5.7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ44971.1 - 7e-13 48.8 0.0 1.5e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ44971.1 - 2.1e-10 41.1 0.0 5.1e-09 36.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ44971.1 - 6.4e-10 39.4 0.0 3.8e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ44971.1 - 1.2e-09 37.9 0.0 3.1e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ44971.1 - 2.1e-07 30.2 0.0 2.7e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ44971.1 - 1.7e-05 25.1 0.0 4.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ44971.1 - 0.00075 18.9 0.0 0.0076 15.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ44971.1 - 0.0017 18.3 0.0 0.0095 15.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ44971.1 - 0.0018 17.3 0.0 0.0059 15.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 KEZ44971.1 - 0.0035 16.8 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KEZ44971.1 - 0.0038 16.3 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 KEZ44971.1 - 0.019 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 KEZ44971.1 - 0.027 14.0 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.15 KEZ44971.1 - 0.053 12.5 0.0 0.25 10.3 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 KEZ44971.1 - 0.077 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 KEZ44971.1 - 0.15 11.6 0.0 36 3.8 0.0 3.3 4 0 0 4 4 4 0 Hypothetical methyltransferase DUF3425 PF11905.3 KEZ44972.1 - 5.3e-27 94.3 0.0 9.1e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PHO4 PF01384.15 KEZ44973.1 - 2.9e-111 371.2 0.0 4.5e-111 370.6 0.0 1.3 1 1 0 1 1 1 1 Phosphate transporter family PBP1_TM PF14812.1 KEZ44973.1 - 0.0017 18.6 0.6 0.0034 17.6 0.4 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4644 PF15486.1 KEZ44973.1 - 0.048 13.6 0.3 0.078 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) CENP-B_dimeris PF09026.5 KEZ44973.1 - 0.41 10.9 10.6 0.77 10.0 7.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rho_GDI PF02115.12 KEZ44973.1 - 0.72 9.2 3.8 1.3 8.4 2.6 1.3 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Ribosomal_60s PF00428.14 KEZ44973.1 - 2 8.8 15.2 4.4 7.7 10.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM176 PF14851.1 KEZ44973.1 - 2 8.0 4.3 5.2 6.7 3.0 1.6 1 0 0 1 1 1 0 FAM176 family PI3K_1B_p101 PF10486.4 KEZ44973.1 - 3.7 4.9 3.3 5.3 4.4 2.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleoplasmin PF03066.10 KEZ44973.1 - 8.2 5.9 14.1 13 5.2 9.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KEZ44973.1 - 8.6 5.9 9.7 13 5.3 6.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region 3Beta_HSD PF01073.14 KEZ44974.1 - 4.4e-19 68.2 0.0 1.8e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ44974.1 - 1.4e-11 44.2 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KEZ44974.1 - 1e-09 37.6 0.1 3.3e-07 29.4 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein adh_short PF00106.20 KEZ44974.1 - 8.3e-07 29.0 0.1 3.5e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KEZ44974.1 - 1.1e-06 28.7 0.1 1.4e-05 25.1 0.1 2.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KEZ44974.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEZ44974.1 - 0.0023 16.8 0.0 0.0039 16.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KEZ44974.1 - 0.0049 15.8 0.0 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain F420_oxidored PF03807.12 KEZ44974.1 - 0.096 13.1 0.0 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 KEZ44975.1 - 3.2e-24 86.1 0.0 1.1e-23 84.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ44975.1 - 9.9e-11 41.5 0.1 2.9e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KEZ44975.1 - 1.2e-08 33.6 0.0 3.4e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ44975.1 - 3e-08 32.9 0.0 1.5e-05 24.0 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ44975.1 - 8.8e-06 25.5 0.2 0.00019 21.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEZ44975.1 - 2.3e-05 24.3 0.0 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ44975.1 - 0.0091 15.1 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KEZ44975.1 - 0.052 12.0 0.1 0.081 11.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 KEZ44975.1 - 0.096 11.5 0.0 0.43 9.4 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD-oxidase_C PF02913.14 KEZ44976.1 - 4e-30 104.9 0.0 6.2e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEZ44976.1 - 3e-26 91.5 0.0 4.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Defensin_2 PF01097.13 KEZ44977.1 - 2e-05 24.2 9.3 3e-05 23.6 6.4 1.3 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.15 KEZ44977.1 - 1.3 9.1 6.4 1.8 8.6 4.5 1.3 1 0 0 1 1 1 0 Gamma-thionin family BTB PF00651.26 KEZ44978.1 - 0.0003 20.7 0.1 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 KEZ44979.1 - 3.3e-34 118.1 23.9 1.2e-33 116.2 17.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KEZ44979.1 - 0.58 10.2 0.0 0.58 10.2 0.0 3.3 3 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding PRP1_N PF06424.7 KEZ44980.1 - 0.0067 16.7 1.6 0.011 16.1 1.1 1.3 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal Ras PF00071.17 KEZ44980.1 - 0.05 13.0 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Ras family ATP-synt_E PF05680.7 KEZ44980.1 - 5.3 7.0 8.9 0.52 10.2 2.1 2.0 2 0 0 2 2 2 0 ATP synthase E chain FAD_binding_3 PF01494.14 KEZ44981.1 - 3.9e-50 170.9 0.0 1.1e-38 133.2 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain DUF2693 PF10902.3 KEZ44981.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) GST_N PF02798.15 KEZ44982.1 - 1.7e-13 50.5 0.0 3.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ44982.1 - 7.9e-13 48.4 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEZ44982.1 - 2.1e-10 40.4 0.0 3.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEZ44982.1 - 7.4e-10 38.6 0.0 2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ44982.1 - 9.2e-08 31.8 0.2 1.5e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEZ44982.1 - 0.0012 19.3 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF664 PF04978.7 KEZ44982.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF664) HsbA PF12296.3 KEZ44983.1 - 0.036 13.9 0.4 0.32 10.8 0.0 2.3 2 1 0 2 2 2 0 Hydrophobic surface binding protein A NPV_P10 PF05531.7 KEZ44983.1 - 0.053 13.7 0.8 0.33 11.2 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HET PF06985.6 KEZ44986.1 - 1e-23 83.9 2.1 1.7e-23 83.2 0.2 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.3 KEZ44986.1 - 4.3e-08 32.1 1.8 8e-08 31.2 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ44987.1 - 7.5e-56 189.3 29.6 7.5e-56 189.3 20.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ44987.1 - 8.6e-09 34.4 20.3 8.6e-09 34.4 14.1 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 KEZ44987.1 - 1.7e-05 23.1 3.1 2.6e-05 22.5 2.1 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 KEZ44987.1 - 0.023 12.7 12.9 0.042 11.9 1.9 3.6 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 KEZ44988.1 - 6.9e-49 166.6 0.0 9.4e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-B_box PF00643.19 KEZ44989.1 - 0.18 11.6 7.3 0.11 12.3 2.2 2.3 2 0 0 2 2 2 0 B-box zinc finger Amidase PF01425.16 KEZ44990.1 - 4.9e-71 239.8 0.0 1.4e-40 139.5 0.0 2.2 1 1 1 2 2 2 2 Amidase S19 PF06756.6 KEZ44990.1 - 0.06 13.2 2.5 1.2 9.0 0.4 2.4 2 0 0 2 2 2 0 Chorion protein S19 C-terminal Gag_p15 PF08723.5 KEZ44990.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Gag protein p15 Aconitase PF00330.15 KEZ44991.1 - 7.8e-52 176.2 0.0 1.3e-23 83.1 0.0 3.1 1 1 2 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEZ44991.1 - 2.6e-27 95.5 0.0 4.7e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MFS_1 PF07690.11 KEZ44992.1 - 1.3e-47 162.2 45.7 2.1e-47 161.5 31.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ44992.1 - 8.6e-20 70.7 32.9 1.5e-18 66.6 3.7 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KEZ44992.1 - 2.1e-05 22.9 27.0 0.00012 20.4 18.8 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KEZ44992.1 - 0.0066 14.8 29.8 0.032 12.6 12.4 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein CPSase_L_D2 PF02786.12 KEZ44993.1 - 2.2e-68 229.6 0.1 4.6e-68 228.6 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KEZ44993.1 - 7.6e-58 195.1 0.0 1.3e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KEZ44993.1 - 7.2e-34 116.2 0.1 1.5e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KEZ44993.1 - 8.6e-30 102.8 0.0 2.1e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KEZ44993.1 - 9.5e-22 77.8 0.2 2e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 KEZ44993.1 - 1.9e-16 59.4 0.7 1.2e-15 56.8 0.2 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KEZ44993.1 - 4.1e-13 48.7 0.0 1.7e-12 46.7 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KEZ44993.1 - 4.1e-11 42.9 0.1 1.8e-10 40.8 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KEZ44993.1 - 4.8e-07 29.3 0.0 0.046 13.4 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KEZ44993.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KEZ44993.1 - 0.00015 21.1 0.0 0.00041 19.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KEZ44993.1 - 0.00067 19.1 0.0 0.0017 17.8 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KEZ44993.1 - 0.0069 16.2 0.1 0.24 11.2 0.0 2.5 1 1 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KEZ44993.1 - 0.073 13.4 0.0 3.9 7.8 0.0 3.2 2 1 1 3 3 3 0 HlyD family secretion protein DUF2484 PF10658.4 KEZ44994.1 - 5.2 7.2 8.2 0.77 9.9 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2484) NAD_binding_6 PF08030.7 KEZ44995.1 - 5.4e-17 62.1 0.0 8.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KEZ44995.1 - 1.2e-12 47.5 0.0 5.7e-06 26.1 0.0 2.8 3 0 0 3 3 3 2 FAD-binding domain Ferric_reduct PF01794.14 KEZ44995.1 - 7.1e-10 39.0 3.6 7.1e-10 39.0 2.5 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KEZ44995.1 - 0.00011 22.7 0.0 0.048 14.2 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain MFS_1 PF07690.11 KEZ44996.1 - 1.1e-29 103.2 43.6 1.6e-27 96.1 22.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HNH_2 PF13391.1 KEZ44996.1 - 8.6e-12 44.6 0.0 7.2e-11 41.7 0.0 2.4 2 0 0 2 2 2 1 HNH endonuclease DUF3377 PF11857.3 KEZ44996.1 - 0.67 9.6 2.1 12 5.6 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) WSC PF01822.14 KEZ44997.1 - 5.5e-38 128.7 46.7 6.6e-16 58.0 5.4 8.5 7 2 1 8 8 8 4 WSC domain Peptidase_S8 PF00082.17 KEZ44997.1 - 6.2e-21 74.7 0.0 6.2e-21 74.7 0.0 2.1 3 0 0 3 3 3 1 Subtilase family Lipase_GDSL_2 PF13472.1 KEZ44997.1 - 4e-13 49.8 0.5 1.7e-12 47.8 0.0 2.4 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family RTA1 PF04479.8 KEZ44999.1 - 8.2e-48 162.8 6.6 1.2e-47 162.3 4.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 KEZ45000.1 - 0.092 11.3 0.1 0.29 9.6 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain DUF998 PF06197.8 KEZ45001.1 - 0.046 13.0 0.3 0.057 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Bac_luciferase PF00296.15 KEZ45002.1 - 1.5e-60 204.9 0.9 2.1e-60 204.4 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 KEZ45003.1 - 3.7e-11 42.3 32.0 3.7e-11 42.3 22.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEZ45003.1 - 8.1e-06 25.4 2.8 8.1e-06 25.4 2.0 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Ank_2 PF12796.2 KEZ45004.1 - 2e-24 85.7 0.4 8.2e-09 35.6 0.0 4.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ45004.1 - 1.2e-19 70.3 7.3 3.5e-07 30.5 0.1 5.8 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ45004.1 - 2.5e-18 65.6 4.7 5.5e-06 26.4 0.1 6.1 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45004.1 - 3.7e-15 54.8 12.8 0.0021 17.7 0.0 7.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 KEZ45004.1 - 1.1e-14 53.0 3.0 0.0069 16.5 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Cation_ATPase_C PF00689.16 KEZ45004.1 - 0.36 10.3 2.2 14 5.1 0.0 2.7 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus DUF1399 PF07173.7 KEZ45005.1 - 1.8e-17 63.9 2.4 7.9e-15 55.3 0.0 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF1399) Lipase_GDSL_2 PF13472.1 KEZ45007.1 - 4.3e-08 33.5 0.4 1.5e-07 31.7 0.3 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AA_permease PF00324.16 KEZ45009.1 - 5.1e-125 417.5 34.3 6.2e-125 417.2 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ45009.1 - 1.4e-45 155.6 37.7 1.7e-45 155.3 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.12 KEZ45009.1 - 0.011 14.2 8.4 0.075 11.5 1.2 2.4 2 0 0 2 2 2 0 Sodium:alanine symporter family OmdA PF13376.1 KEZ45011.1 - 1.2e-15 56.8 0.4 2.2e-15 56.0 0.2 1.4 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated TPR_12 PF13424.1 KEZ45012.1 - 3.3e-71 235.2 26.3 1.8e-18 66.2 0.7 4.9 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ45012.1 - 2.3e-67 221.1 20.2 9e-14 50.8 0.4 8.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ45012.1 - 6e-27 91.2 23.0 4.3e-06 26.1 0.2 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ45012.1 - 2.3e-25 88.0 16.5 2e-09 36.9 0.7 5.4 2 1 4 6 6 6 6 TPR repeat Patatin PF01734.17 KEZ45012.1 - 5.6e-25 88.4 0.3 3.8e-24 85.7 0.0 2.6 3 1 0 3 3 2 1 Patatin-like phospholipase TPR_2 PF07719.12 KEZ45012.1 - 6.4e-24 81.9 17.9 0.0011 18.7 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ45012.1 - 3e-22 77.2 22.3 0.00032 20.1 0.3 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ45012.1 - 1.1e-20 73.7 14.3 1.3e-07 32.0 1.0 5.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_3 PF07720.7 KEZ45012.1 - 8.1e-17 60.6 5.8 0.047 13.4 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ45012.1 - 3e-15 55.3 18.1 0.092 13.4 0.0 8.2 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ45012.1 - 9.2e-14 50.4 0.1 0.9 10.1 0.0 7.5 8 0 0 8 8 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ45012.1 - 4.5e-13 48.7 0.0 7.4e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KEZ45012.1 - 1.9e-12 47.1 10.1 2.7e-05 24.1 0.6 4.3 1 1 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KEZ45012.1 - 3.2e-12 46.5 23.8 2.5e-05 24.5 1.2 5.5 6 1 1 7 7 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ45012.1 - 8.6e-10 38.0 15.1 1.7 9.0 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat PPR PF01535.15 KEZ45012.1 - 4.6e-08 32.5 0.1 1.3 9.2 0.0 6.4 6 0 0 6 6 6 1 PPR repeat TPR_8 PF13181.1 KEZ45012.1 - 1e-07 31.2 15.7 2.9 7.8 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.1 KEZ45012.1 - 9.5e-07 28.9 0.4 3.8e-06 27.0 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain PPR_2 PF13041.1 KEZ45012.1 - 3e-06 27.1 1.3 4.1 7.4 0.0 5.3 5 0 0 5 5 5 1 PPR repeat family Fis1_TPR_C PF14853.1 KEZ45012.1 - 0.001 18.8 12.1 0.053 13.4 0.1 5.7 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KEZ45012.1 - 0.0034 17.7 15.1 41 4.9 0.1 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Cas_Cmr5 PF09701.5 KEZ45012.1 - 0.0057 16.8 0.1 0.088 12.9 0.0 2.6 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Cmr5) PPR_1 PF12854.2 KEZ45012.1 - 0.021 14.3 0.0 5.3 6.6 0.0 4.4 6 0 0 6 6 5 0 PPR repeat DUF4404 PF14357.1 KEZ45012.1 - 0.051 13.9 6.8 26 5.2 0.1 5.5 3 1 1 5 5 4 0 Domain of unknown function (DUF4404) PPR_3 PF13812.1 KEZ45012.1 - 0.058 13.7 1.3 27 5.3 0.0 5.0 6 0 0 6 6 4 0 Pentatricopeptide repeat domain SHNi-TPR PF10516.4 KEZ45012.1 - 0.1 11.8 10.1 0.42 9.8 0.0 4.8 6 0 0 6 6 6 0 SHNi-TPR Tcf25 PF04910.9 KEZ45012.1 - 1.1 8.1 6.2 6.1 5.6 0.0 3.5 1 1 4 5 5 5 0 Transcriptional repressor TCF25 Sugar_tr PF00083.19 KEZ45013.1 - 1.3e-17 63.5 6.8 2.8e-11 42.6 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45013.1 - 0.0041 15.8 4.8 0.0064 15.2 3.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 KEZ45014.1 - 2.9e-14 53.3 0.0 3.4e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ45014.1 - 6.8e-07 29.3 0.0 8e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ45014.1 - 1.5e-05 24.7 0.3 1.7e-05 24.5 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF3701 PF12482.3 KEZ45014.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 1 0 1 1 1 0 Phage integrase protein Fungal_trans PF04082.13 KEZ45015.1 - 5.9e-09 35.1 0.0 1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ45016.1 - 6.3e-34 117.2 28.3 6.3e-34 117.2 19.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SLAC1 PF03595.12 KEZ45017.1 - 3.6e-92 308.5 45.5 4.3e-92 308.2 31.5 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Acetyltransf_3 PF13302.1 KEZ45017.1 - 1.2e-10 41.6 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ilar_coat PF01787.11 KEZ45017.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein Glyco_hydro_61 PF03443.9 KEZ45018.1 - 2.3e-42 145.3 0.6 1.3e-39 136.2 0.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Ribonuclease_T2 PF00445.13 KEZ45020.1 - 1.9e-47 161.3 2.7 3.1e-47 160.6 1.9 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family DUF538 PF04398.7 KEZ45020.1 - 0.025 14.8 0.6 0.3 11.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF538 Ank_5 PF13857.1 KEZ45021.1 - 1.1e-30 104.9 3.0 6.4e-08 32.6 0.0 6.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEZ45021.1 - 2e-30 104.9 0.0 2.5e-15 56.5 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ45021.1 - 3.2e-28 97.5 0.5 2.2e-10 40.7 0.0 6.8 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45021.1 - 3.3e-26 89.7 0.2 3.8e-05 23.2 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KEZ45021.1 - 6.6e-21 72.3 0.0 0.0029 17.6 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Amidase PF01425.16 KEZ45023.1 - 2.7e-105 352.7 0.0 3.5e-105 352.4 0.0 1.0 1 0 0 1 1 1 1 Amidase APH PF01636.18 KEZ45024.1 - 7e-14 52.1 0.1 1.9e-13 50.7 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ45024.1 - 0.034 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_N PF00732.14 KEZ45025.1 - 3.1e-44 151.3 0.0 4.5e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ45025.1 - 3e-30 105.4 0.0 5.3e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ45025.1 - 0.064 12.1 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ45025.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain BBE PF08031.7 KEZ45026.1 - 1.1e-11 44.4 0.5 2.4e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.18 KEZ45026.1 - 1.5e-05 24.5 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAR1 PF03101.10 KEZ45027.1 - 7.4e-07 29.6 0.4 2.3e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain Sugar_tr PF00083.19 KEZ45028.1 - 3.1e-104 349.0 22.3 1.1e-103 347.2 15.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45028.1 - 1.7e-18 66.4 32.4 1.6e-16 60.0 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3 PF00933.16 KEZ45029.1 - 1.4e-54 185.1 0.0 1.9e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ45029.1 - 2.3e-40 138.5 0.0 3.3e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ45029.1 - 1.9e-15 56.5 0.1 3.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 KEZ45030.1 - 8e-30 103.7 32.3 1.3e-29 103.0 22.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45030.1 - 1.1e-09 37.4 22.8 1.7e-09 36.7 15.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MRP-S26 PF14943.1 KEZ45030.1 - 0.14 11.6 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Fungal_trans PF04082.13 KEZ45031.1 - 1.7e-21 76.2 0.0 2.3e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45031.1 - 3.3e-08 33.2 9.3 7.2e-08 32.2 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KEZ45032.1 - 8.6e-58 195.9 0.0 1.1e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL_4 PF13577.1 KEZ45033.1 - 1.3e-07 31.5 0.9 2e-07 30.9 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KEZ45033.1 - 0.0045 17.0 0.8 0.0061 16.5 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain HIPIP PF01355.12 KEZ45033.1 - 0.06 13.4 0.2 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 High potential iron-sulfur protein ESSS PF10183.4 KEZ45033.1 - 0.078 13.3 0.1 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) p450 PF00067.17 KEZ45034.1 - 2.9e-53 181.0 0.0 3.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 STb_secrete PF09075.5 KEZ45034.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory AMP-binding PF00501.23 KEZ45035.1 - 1.8e-15 56.2 0.0 9.8e-15 53.8 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Form_Nir_trans PF01226.12 KEZ45036.1 - 4.9e-75 251.6 16.5 5.6e-75 251.4 11.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Sdh_cyt PF01127.17 KEZ45036.1 - 3.9 7.3 11.6 0.14 11.9 3.6 1.9 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF713 PF05218.9 KEZ45037.1 - 0.21 11.3 1.6 2.9 7.5 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF713) Ribonuc_L-PSP PF01042.16 KEZ45038.1 - 3.6e-06 26.7 0.0 5.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP ATP-synt_D PF01813.12 KEZ45038.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase subunit D Glyco_hydro_3 PF00933.16 KEZ45039.1 - 1.3e-76 257.4 0.0 1.9e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ45039.1 - 1.2e-58 198.3 0.0 3.2e-58 196.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ45039.1 - 1.2e-16 60.4 0.0 2.6e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KEZ45039.1 - 1.8e-06 27.6 0.0 3.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.19 KEZ45040.1 - 3e-41 141.4 16.6 1.1e-30 106.6 7.5 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45040.1 - 5.3e-12 45.1 15.6 6e-09 35.0 5.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Brr6_like_C_C PF10104.4 KEZ45040.1 - 0.46 9.9 1.9 1.2 8.7 1.3 1.6 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Zn_clus PF00172.13 KEZ45041.1 - 1.5e-07 31.1 5.7 2.7e-07 30.3 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain gpW PF02831.10 KEZ45041.1 - 0.025 14.1 0.1 11 5.6 0.0 2.7 3 0 0 3 3 3 0 gpW Sugar_tr PF00083.19 KEZ45042.1 - 3.1e-56 190.8 28.1 3.5e-26 91.7 8.0 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45042.1 - 3.1e-18 65.6 35.6 1.3e-11 43.7 9.8 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Brr6_like_C_C PF10104.4 KEZ45042.1 - 0.38 10.2 7.5 0.032 13.7 1.2 2.1 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain MFS_1 PF07690.11 KEZ45043.1 - 1.8e-33 115.6 15.4 1.8e-33 115.6 10.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily FtsH_ext PF06480.10 KEZ45043.1 - 0.072 13.2 0.6 0.34 11.0 0.0 2.4 2 0 0 2 2 2 0 FtsH Extracellular DUF1228 PF06779.9 KEZ45043.1 - 3.5 7.7 6.4 2.2 8.3 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1228) CAP59_mtransfer PF11735.3 KEZ45044.1 - 7e-64 215.3 0.0 9.5e-64 214.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MFS_1 PF07690.11 KEZ45045.1 - 8.8e-32 110.1 20.0 8.8e-32 110.1 13.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 KEZ45046.1 - 4.8e-58 196.8 0.0 8.2e-46 156.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF655 PF04919.7 KEZ45046.1 - 0.033 13.9 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF655) Glyoxalase_2 PF12681.2 KEZ45047.1 - 3.2e-11 43.7 0.0 1.6e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KEZ45047.1 - 4.9e-11 42.7 0.0 1.1e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KEZ45047.1 - 4e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CHORD PF04968.7 KEZ45049.1 - 0.009 16.2 2.4 0.016 15.4 0.1 2.2 2 0 0 2 2 2 1 CHORD Ank_2 PF12796.2 KEZ45050.1 - 1.5e-10 41.2 0.1 3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ45050.1 - 2.3e-10 40.6 0.1 1.3e-09 38.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45050.1 - 2.9e-10 39.4 0.6 2e-07 30.4 0.2 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEZ45050.1 - 9.9e-10 38.3 0.8 8.9e-09 35.3 0.3 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ45050.1 - 1.1e-07 31.3 0.1 6.9e-05 22.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat PLDc_2 PF13091.1 KEZ45050.1 - 1.4e-07 31.2 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain SSF PF00474.12 KEZ45051.1 - 2.9e-24 85.4 24.9 2.9e-24 85.4 17.2 1.9 2 0 0 2 2 2 1 Sodium:solute symporter family NmrA PF05368.8 KEZ45052.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ45052.1 - 6.4e-13 49.1 0.4 6.5e-12 45.8 0.2 2.4 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ45052.1 - 0.016 13.9 0.0 0.031 13.0 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KEZ45052.1 - 0.053 13.1 0.2 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 KR domain SET PF00856.23 KEZ45053.1 - 0.0036 17.6 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Transferase PF02458.10 KEZ45054.1 - 8.2e-08 31.1 0.0 1.7e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Transferase family Methyltransf_23 PF13489.1 KEZ45055.1 - 2.8e-19 69.3 0.0 4.5e-19 68.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45055.1 - 9.2e-12 45.2 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45055.1 - 4.3e-11 43.1 0.0 1.1e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45055.1 - 5.7e-10 38.9 0.0 9.1e-09 35.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45055.1 - 1.1e-09 38.8 0.0 1.4e-08 35.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ45055.1 - 2.3e-07 31.0 0.0 5.3e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45055.1 - 2.5e-07 30.0 0.0 2.3e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEZ45055.1 - 1e-05 24.7 0.0 8.7e-05 21.6 0.0 2.3 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.9 KEZ45055.1 - 0.00059 19.2 0.0 0.0046 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ45055.1 - 0.0045 17.0 0.0 0.13 12.3 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain FtsJ PF01728.14 KEZ45055.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 KEZ45055.1 - 0.07 12.6 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 KEZ45055.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.11 KEZ45056.1 - 5.7e-22 77.9 54.4 2.2e-16 59.5 19.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KEZ45056.1 - 4.7e-11 41.5 20.6 5.7e-11 41.3 13.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Chromo PF00385.19 KEZ45060.1 - 3.2e-06 26.7 5.8 0.0029 17.2 0.4 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_31 PF01055.21 KEZ45062.1 - 2.9e-46 158.2 4.0 2e-27 96.1 0.0 3.2 2 1 1 3 3 3 3 Glycosyl hydrolases family 31 HET PF06985.6 KEZ45062.1 - 5.9e-32 110.7 0.5 5.9e-32 110.7 0.4 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Gal_mutarotas_2 PF13802.1 KEZ45062.1 - 3e-13 49.3 0.0 9.5e-13 47.8 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like HSD3 PF15244.1 KEZ45062.1 - 0.062 12.5 0.4 0.097 11.8 0.3 1.2 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase Tyrosinase PF00264.15 KEZ45063.1 - 4.4e-32 112.0 0.0 6.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.11 KEZ45064.1 - 4e-23 81.6 55.7 1.5e-20 73.2 31.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.14 KEZ45065.1 - 3.5e-24 84.9 0.0 6.2e-15 54.3 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KEZ45065.1 - 0.00019 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KEZ45065.1 - 0.049 12.5 0.0 0.4 9.5 0.0 2.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) 2OG-FeII_Oxy PF03171.15 KEZ45067.1 - 1.8e-14 53.7 0.1 3e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KEZ45067.1 - 5.2e-09 36.6 0.0 8.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Polysacc_deac_2 PF04748.8 KEZ45067.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Amidohydro_4 PF13147.1 KEZ45068.1 - 1.1e-10 42.0 5.9 1.1e-10 42.0 4.1 3.7 3 1 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 KEZ45068.1 - 3.2e-05 23.7 2.6 0.00029 20.6 1.8 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEZ45068.1 - 0.00023 20.9 0.5 0.00023 20.9 0.3 3.6 4 0 0 4 4 4 1 Amidohydrolase Amidohydro_3 PF07969.6 KEZ45068.1 - 0.0011 18.3 1.7 0.0012 18.1 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family GMC_oxred_N PF00732.14 KEZ45069.1 - 7e-78 261.7 0.0 9.6e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ45069.1 - 9.9e-36 123.1 0.0 4e-35 121.2 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KEZ45069.1 - 1.2e-06 27.6 0.0 0.0042 16.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ45069.1 - 0.00028 19.8 0.1 0.39 9.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KEZ45069.1 - 0.0016 17.4 0.1 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KEZ45069.1 - 0.0046 16.0 0.0 0.032 13.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ45069.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1706 PF08020.6 KEZ45070.1 - 0.033 13.6 0.2 0.062 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) OTT_1508_deam PF14441.1 KEZ45071.1 - 9.4e-15 54.6 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Fungal_trans PF04082.13 KEZ45072.1 - 1.3e-13 50.4 0.3 2.1e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEZ45072.1 - 0.084 13.2 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type adh_short_C2 PF13561.1 KEZ45073.1 - 6.1e-27 94.9 0.1 7e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ45073.1 - 1.6e-24 86.7 2.1 2.4e-24 86.1 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ45073.1 - 3.1e-10 40.0 0.8 3.1e-10 40.0 0.5 1.6 2 0 0 2 2 2 1 KR domain ThiF PF00899.16 KEZ45073.1 - 0.16 11.7 1.7 0.75 9.6 0.4 2.2 1 1 1 2 2 2 0 ThiF family Amidase PF01425.16 KEZ45074.1 - 8.4e-92 308.3 0.1 1.2e-91 307.8 0.1 1.2 1 0 0 1 1 1 1 Amidase ADH_N PF08240.7 KEZ45075.1 - 4.5e-23 81.0 1.0 1.1e-22 79.7 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ45075.1 - 1.5e-14 53.6 0.1 2.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ45075.1 - 0.0037 16.4 0.1 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 KEZ45075.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain 3HCDH_N PF02737.13 KEZ45075.1 - 0.12 12.0 0.2 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_deac_1 PF01522.16 KEZ45076.1 - 2.1e-22 79.0 0.0 4.5e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 KEZ45076.1 - 0.054 12.9 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 KEZ45076.1 - 0.14 10.1 0.0 0.21 9.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Aa_trans PF01490.13 KEZ45077.1 - 9.7e-29 100.0 33.4 1.2e-28 99.7 23.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 KEZ45077.1 - 2.9e-05 22.8 39.2 6.3e-05 21.6 22.1 2.9 1 1 1 2 2 2 1 Amino acid permease GWT1 PF06423.7 KEZ45077.1 - 4.1 7.5 12.7 1.8 8.6 2.2 3.3 3 1 0 3 3 3 0 GWT1 Abhydrolase_6 PF12697.2 KEZ45078.1 - 2.8e-15 56.8 1.2 3.7e-15 56.4 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ45078.1 - 2.7e-07 30.4 0.1 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DegV PF02645.11 KEZ45078.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein, DegV family COG1307 PGAP1 PF07819.8 KEZ45078.1 - 0.05 13.1 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Tubulin PF00091.20 KEZ45078.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain adh_short PF00106.20 KEZ45079.1 - 2.8e-18 66.4 0.2 3.7e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ45079.1 - 6.9e-14 52.1 0.0 9.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KEZ45079.1 - 2.2e-05 24.5 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding ACR_tran PF00873.14 KEZ45080.1 - 0.17 9.2 1.3 0.23 8.8 0.9 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family APH PF01636.18 KEZ45081.1 - 0.00027 20.7 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1985 PF09331.6 KEZ45081.1 - 0.0051 16.6 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1985) Fructosamin_kin PF03881.9 KEZ45081.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase AAA PF00004.24 KEZ45082.1 - 5.9e-08 32.9 0.0 3.9e-07 30.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KEZ45082.1 - 5.1e-07 30.5 0.0 2.3e-06 28.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ45082.1 - 6.5e-05 23.0 0.0 0.00017 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KEZ45082.1 - 7.2e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ45082.1 - 0.00012 21.7 0.0 0.00029 20.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEZ45082.1 - 0.0002 21.6 0.5 0.0026 18.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KEZ45082.1 - 0.0023 17.6 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KEZ45082.1 - 0.0032 17.6 0.0 0.0089 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEZ45082.1 - 0.004 17.1 0.0 0.027 14.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KEZ45082.1 - 0.0067 16.3 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KEZ45082.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KEZ45082.1 - 0.0085 15.2 0.2 0.027 13.6 0.0 1.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEZ45082.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.7 KEZ45082.1 - 0.02 13.9 0.0 0.05 12.6 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KEZ45082.1 - 0.035 13.7 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain KTI12 PF08433.5 KEZ45082.1 - 0.05 12.8 0.0 0.15 11.2 0.0 1.8 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 KEZ45082.1 - 0.052 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KEZ45082.1 - 0.059 12.0 0.0 0.095 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KEZ45082.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KEZ45082.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CPT PF07931.7 KEZ45082.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sulfatase PF00884.18 KEZ45083.1 - 6.6e-71 239.0 0.0 9.8e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Ank_2 PF12796.2 KEZ45083.1 - 2.3e-49 165.6 6.5 7.4e-11 42.2 0.2 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ45083.1 - 2.1e-34 114.0 11.9 2e-05 24.3 0.0 12.1 11 1 0 11 11 11 4 Ankyrin repeat Ank_4 PF13637.1 KEZ45083.1 - 9.4e-33 112.0 11.3 1.4e-05 25.4 0.1 8.3 4 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ45083.1 - 1.7e-32 110.6 12.6 1.2e-08 34.9 0.0 9.2 7 3 3 10 10 9 5 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45083.1 - 7.8e-32 107.4 19.4 7.9e-08 31.7 0.0 10.6 10 1 0 10 10 10 6 Ankyrin repeat AAA_16 PF13191.1 KEZ45083.1 - 6.8e-10 39.2 0.1 1.3e-08 35.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KEZ45083.1 - 5.8e-07 29.3 0.0 1e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ45083.1 - 4.6e-05 23.5 0.0 0.0002 21.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ45083.1 - 0.0031 18.3 0.0 0.016 16.0 0.0 2.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KEZ45083.1 - 0.0037 16.2 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KEZ45083.1 - 0.0048 16.6 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KEZ45083.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 KEZ45083.1 - 0.0054 16.2 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain Sulfatase_C PF14707.1 KEZ45083.1 - 0.0079 16.4 0.2 0.056 13.7 0.1 2.3 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 KEZ45083.1 - 0.015 14.6 0.0 4 6.6 0.0 2.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KEZ45083.1 - 0.018 13.4 0.0 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) AAA_18 PF13238.1 KEZ45083.1 - 0.022 15.0 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEZ45083.1 - 0.028 14.6 0.0 1.2 9.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEZ45083.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KEZ45083.1 - 0.044 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 KEZ45083.1 - 0.069 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.18 KEZ45083.1 - 0.083 12.8 0.0 0.43 10.5 0.0 2.4 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KEZ45083.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KEZ45083.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 KEZ45083.1 - 0.14 11.0 0.0 0.93 8.4 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain ArgK PF03308.11 KEZ45083.1 - 0.15 10.7 0.0 0.45 9.2 0.0 1.8 1 0 0 1 1 1 0 ArgK protein Sugar_tr PF00083.19 KEZ45084.1 - 2.8e-79 266.8 12.9 5.3e-79 265.8 8.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45084.1 - 7.6e-17 61.0 15.0 7.6e-17 61.0 10.4 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ45084.1 - 0.23 9.5 6.3 0.61 8.2 0.2 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Romo1 PF10247.4 KEZ45084.1 - 0.85 9.8 7.2 11 6.2 0.0 3.5 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Acyl_transf_3 PF01757.17 KEZ45086.1 - 0.079 11.7 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Acyltransferase family Shisa PF13908.1 KEZ45087.1 - 0.0049 17.0 0.0 0.0097 16.0 0.0 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KEZ45087.1 - 0.042 12.1 0.0 0.06 11.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E GMC_oxred_N PF00732.14 KEZ45088.1 - 3.4e-50 170.8 0.0 4.5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ45088.1 - 1.1e-31 110.0 0.0 1.9e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ45088.1 - 1.8e-05 23.8 0.0 0.058 12.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ45088.1 - 0.0012 18.8 0.1 0.0067 16.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ45088.1 - 0.0042 16.0 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEZ45088.1 - 0.016 15.0 0.1 0.12 12.1 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KEZ45088.1 - 0.043 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hormone_recep PF00104.25 KEZ45088.1 - 0.063 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor GIDA PF01134.17 KEZ45088.1 - 0.086 11.6 0.0 6.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KEZ45088.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Dioxygenase_C PF00775.16 KEZ45089.1 - 1.5e-11 43.9 3.0 1.9e-10 40.3 2.1 2.2 1 1 0 1 1 1 1 Dioxygenase MFS_1 PF07690.11 KEZ45090.1 - 3e-40 138.0 45.4 3e-40 138.0 31.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ45091.1 - 3.1e-09 36.0 0.0 2e-08 33.4 0.0 2.1 1 1 1 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KEZ45092.1 - 8.5e-14 51.0 1.0 8.5e-14 51.0 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Spherulin4 PF12138.3 KEZ45093.1 - 6.2e-25 88.0 0.3 2.7e-24 85.9 0.2 2.0 1 1 0 1 1 1 1 Spherulation-specific family 4 fn3 PF00041.16 KEZ45093.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain TM_helix PF05552.7 KEZ45095.1 - 0.048 13.3 0.3 0.048 13.3 0.2 2.9 3 1 0 3 3 3 0 Conserved TM helix MARVEL PF01284.18 KEZ45095.1 - 0.66 9.7 10.9 1.1 9.1 7.6 1.4 1 0 0 1 1 1 0 Membrane-associating domain Fungal_trans PF04082.13 KEZ45096.1 - 4e-16 58.6 1.9 7.1e-16 57.8 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45096.1 - 2e-09 37.1 11.9 3.9e-09 36.2 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 KEZ45096.1 - 6 6.6 7.9 10 5.8 5.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Carboxyl_trans PF01039.17 KEZ45097.1 - 4.4e-36 124.2 0.0 6.9e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_M PF02770.14 KEZ45097.1 - 1.3e-20 72.6 1.2 2.6e-20 71.6 0.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KEZ45097.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain CMD PF02627.15 KEZ45098.1 - 0.023 14.5 0.2 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DUF3500 PF12006.3 KEZ45099.1 - 3.5e-88 295.5 0.0 4.2e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Fungal_trans PF04082.13 KEZ45100.1 - 3.3e-10 39.2 1.0 1.4e-05 24.0 0.2 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF4470 PF14737.1 KEZ45101.1 - 3.7e-23 81.1 0.0 1.1e-22 79.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) E1-E2_ATPase PF00122.15 KEZ45102.1 - 1.3e-60 204.2 8.7 1.3e-60 204.2 6.0 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ45102.1 - 5.8e-29 102.0 0.1 4.1e-23 82.9 0.0 2.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KEZ45102.1 - 5.9e-25 87.8 5.7 5.9e-25 87.8 3.9 2.9 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KEZ45102.1 - 6.7e-18 64.4 0.0 2e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KEZ45102.1 - 1.8e-16 59.3 0.1 9.2e-16 57.0 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KEZ45102.1 - 1.4e-13 51.4 0.0 3.4e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ45102.1 - 0.00012 21.8 0.2 0.00023 20.8 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Spore_IV_A PF09547.5 KEZ45102.1 - 0.042 12.5 0.0 0.073 11.7 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) PI3K_C2 PF00792.19 KEZ45102.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 DUF1980 PF09323.5 KEZ45102.1 - 0.69 9.6 2.5 40 3.8 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) AAA PF00004.24 KEZ45103.1 - 1.1e-18 67.7 0.0 2.9e-18 66.3 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ45103.1 - 0.00017 21.7 0.0 0.00067 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ45103.1 - 0.00032 21.5 0.0 0.0016 19.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KEZ45103.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEZ45103.1 - 0.002 18.1 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 KEZ45103.1 - 0.0031 16.9 0.2 0.058 12.8 0.1 2.6 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.1 KEZ45103.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KEZ45103.1 - 0.015 15.1 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEZ45103.1 - 0.018 14.1 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KEZ45103.1 - 0.024 14.0 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 KEZ45103.1 - 0.027 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 KEZ45103.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 KEZ45103.1 - 0.048 12.7 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 KEZ45103.1 - 0.053 13.4 0.0 1.1 9.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 KEZ45103.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ45103.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase His_Phos_1 PF00300.17 KEZ45106.1 - 2.9e-08 33.9 0.0 3.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AOX PF01786.12 KEZ45107.1 - 1.9e-87 292.0 0.0 2.3e-87 291.7 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Zn_clus PF00172.13 KEZ45108.1 - 2.9e-08 33.4 8.8 7.7e-08 32.1 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ45108.1 - 0.0014 17.5 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KEZ45109.1 - 4.1e-84 282.7 26.0 4.7e-84 282.5 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45109.1 - 2.6e-21 75.7 31.0 2.6e-21 75.7 21.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ45109.1 - 5.5e-05 21.7 23.6 0.00064 18.2 2.6 4.0 2 2 2 4 4 4 3 MFS/sugar transport protein TauD PF02668.11 KEZ45110.1 - 8.2e-49 166.5 0.7 9.5e-49 166.3 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.1 KEZ45110.1 - 0.024 15.1 0.0 0.48 10.9 0.0 2.3 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal MotCF PF09158.5 KEZ45111.1 - 0.14 11.8 0.1 7.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage T4 MotA, C-terminal Pkinase PF00069.20 KEZ45113.1 - 8e-21 74.3 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45113.1 - 1.5e-11 43.8 0.0 4.6e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FG-GAP PF01839.18 KEZ45113.1 - 1.5e-08 34.0 17.4 0.011 15.4 0.1 4.3 5 0 0 5 5 5 3 FG-GAP repeat VCBS PF13517.1 KEZ45113.1 - 5.1e-08 33.1 19.5 1.1e-06 28.9 2.4 3.8 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KEZ45113.1 - 0.52 9.7 5.6 8.8 5.7 0.1 3.5 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region CorA PF01544.13 KEZ45114.1 - 0.00012 21.2 2.0 0.00046 19.3 0.1 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Not3 PF04065.10 KEZ45114.1 - 0.0077 15.5 0.5 0.019 14.2 0.1 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component MFS_2 PF13347.1 KEZ45114.1 - 0.011 14.1 1.3 0.015 13.7 0.9 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Herpes_BLRF2 PF05812.7 KEZ45114.1 - 0.011 15.5 0.6 0.029 14.1 0.3 1.8 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein LYTB PF02401.13 KEZ45114.1 - 0.029 13.2 0.4 0.048 12.5 0.3 1.2 1 0 0 1 1 1 0 LytB protein FtsX PF02687.16 KEZ45114.1 - 0.04 13.6 1.0 0.066 12.9 0.7 1.3 1 0 0 1 1 1 0 FtsX-like permease family CCDC-167 PF15188.1 KEZ45114.1 - 0.052 13.4 0.8 0.88 9.5 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.20 KEZ45115.1 - 2.9e-17 62.6 0.0 5.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45115.1 - 1.5e-06 27.5 0.0 5.3e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3632 PF12311.3 KEZ45116.1 - 5.3e-18 65.4 1.2 4.1e-09 36.5 0.1 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3632) NACHT PF05729.7 KEZ45119.1 - 0.00073 19.2 0.1 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain CitT PF12431.3 KEZ45119.1 - 0.14 12.2 0.1 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator AA_permease PF00324.16 KEZ45120.1 - 3.7e-102 342.1 43.0 3.1e-101 339.0 29.8 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ45120.1 - 5.9e-32 110.7 36.0 8.4e-32 110.2 24.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4436 PF14494.1 KEZ45120.1 - 0.1 11.8 0.5 0.23 10.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF788 PF05620.6 KEZ45120.1 - 0.34 10.7 4.8 4.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Aminotran_1_2 PF00155.16 KEZ45121.1 - 7.2e-40 137.0 0.0 8.5e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ45121.1 - 0.033 13.3 0.0 0.085 11.9 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase Tannase PF07519.6 KEZ45122.1 - 8.7e-76 255.5 0.0 1e-37 129.9 0.0 2.0 1 1 1 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEZ45122.1 - 9.9e-07 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ45122.1 - 4.7e-06 25.9 0.0 0.093 11.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ45122.1 - 0.0045 16.7 0.0 0.018 14.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ45122.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chromo PF00385.19 KEZ45123.1 - 2.7e-12 46.1 2.0 4.2e-05 23.1 0.3 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Nop14 PF04147.7 KEZ45123.1 - 0.024 12.5 15.5 0.033 12.1 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KEZ45123.1 - 0.24 9.4 8.1 0.32 8.9 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein GOLD_2 PF13897.1 KEZ45123.1 - 1 9.6 3.9 3 8.0 2.7 1.8 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Thi4 PF01946.12 KEZ45124.1 - 2.3e-103 344.2 0.1 2.7e-103 344.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KEZ45124.1 - 4.4e-08 32.4 0.9 8.4e-06 24.9 0.9 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ45124.1 - 0.00014 20.9 1.0 0.00054 19.0 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KEZ45124.1 - 0.0002 20.3 2.3 0.0062 15.4 0.6 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ45124.1 - 0.0003 20.7 0.6 0.00075 19.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ45124.1 - 0.00049 20.2 0.1 0.00078 19.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ45124.1 - 0.00051 19.9 0.2 0.00077 19.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ45124.1 - 0.00087 19.0 1.3 0.0019 17.9 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KEZ45124.1 - 0.0028 16.8 0.2 0.0057 15.7 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ45124.1 - 0.069 11.6 0.7 0.11 10.9 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein GMC_oxred_N PF00732.14 KEZ45126.1 - 5.3e-55 186.6 0.0 6.8e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ45126.1 - 1.5e-36 125.8 0.0 2.6e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ45126.1 - 4.1e-06 25.9 0.1 0.0014 17.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ45126.1 - 6.7e-05 21.9 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KEZ45126.1 - 0.0032 17.5 0.1 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ45126.1 - 0.0037 17.2 0.8 0.012 15.6 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HHH PF00633.18 KEZ45126.1 - 0.018 14.7 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HI0933_like PF03486.9 KEZ45126.1 - 0.1 11.0 0.7 0.33 9.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 KEZ45126.1 - 0.55 9.0 1.8 6.8 5.4 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NDUF_B7 PF05676.8 KEZ45127.1 - 8.6e-32 108.3 4.3 1e-31 108.1 3.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KEZ45127.1 - 0.0094 15.7 2.2 0.012 15.3 1.4 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GTP_cyclohydro2 PF00925.15 KEZ45129.1 - 9.1e-57 190.9 0.0 7.3e-52 175.0 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II PTR2 PF00854.16 KEZ45130.1 - 5.4e-44 150.4 10.5 9.6e-43 146.3 4.5 3.1 1 1 1 2 2 2 1 POT family MFS_1 PF07690.11 KEZ45130.1 - 2.3e-09 36.4 14.5 2.3e-09 36.4 10.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0126 PF03458.8 KEZ45130.1 - 0.051 13.2 6.2 0.071 12.7 0.1 3.6 2 1 1 3 3 3 0 UPF0126 domain GFO_IDH_MocA PF01408.17 KEZ45132.1 - 5.5e-15 55.9 0.0 9.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SGL PF08450.7 KEZ45133.1 - 3.8e-26 91.9 0.1 3.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KEZ45133.1 - 0.00038 20.3 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 Arylesterase Str_synth PF03088.11 KEZ45133.1 - 0.0024 17.8 0.0 0.011 15.7 0.0 2.2 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.16 KEZ45133.1 - 0.24 11.4 4.8 5.5 7.1 0.0 4.1 5 0 0 5 5 5 0 NHL repeat Mito_fiss_reg PF05308.6 KEZ45133.1 - 0.52 9.6 1.5 0.73 9.1 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Methyltransf_23 PF13489.1 KEZ45134.1 - 6.9e-11 42.1 0.0 2.8e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45134.1 - 0.00077 19.0 0.0 0.0042 16.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45134.1 - 0.0028 18.0 0.0 0.0054 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ABC2_membrane PF01061.19 KEZ45135.1 - 6.6e-51 172.4 56.8 5.8e-35 120.3 8.1 4.8 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEZ45135.1 - 3.9e-26 91.9 0.0 6.4e-14 52.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KEZ45135.1 - 2.2e-19 69.0 1.8 4.6e-17 61.5 0.0 3.0 2 0 0 2 2 2 1 CDR ABC transporter AAA_25 PF13481.1 KEZ45135.1 - 1.9e-06 27.4 0.1 0.016 14.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KEZ45135.1 - 4.6e-05 23.5 0.2 0.035 14.2 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEZ45135.1 - 0.00013 21.8 0.2 0.054 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ45135.1 - 0.00014 21.9 0.8 0.7 9.8 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KEZ45135.1 - 0.0012 19.6 0.0 0.33 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEZ45135.1 - 0.0014 17.8 0.0 0.007 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEZ45135.1 - 0.0017 17.8 0.2 0.77 9.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KEZ45135.1 - 0.0029 16.7 5.9 0.0029 16.7 4.1 3.4 3 0 0 3 3 3 1 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.13 KEZ45135.1 - 0.0065 15.9 0.1 1.6 8.1 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_21 PF13304.1 KEZ45135.1 - 0.0081 16.1 0.3 0.31 10.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KEZ45135.1 - 0.013 15.1 0.2 0.18 11.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KEZ45135.1 - 0.018 15.3 0.0 0.75 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEZ45135.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KEZ45135.1 - 0.065 12.6 1.0 0.21 11.0 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 KEZ45135.1 - 0.077 13.4 0.0 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF4423 PF14394.1 KEZ45135.1 - 0.092 12.2 0.1 17 4.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) NACHT PF05729.7 KEZ45135.1 - 0.11 12.1 1.4 0.74 9.4 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 KEZ45135.1 - 0.24 10.4 0.0 0.76 8.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 KEZ45135.1 - 0.24 11.3 0.0 17 5.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DAHP_synth_2 PF01474.11 KEZ45136.1 - 9.4e-114 380.1 0.0 1.4e-73 247.7 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family DAHP_synth_1 PF00793.15 KEZ45136.1 - 0.069 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 DAHP synthetase I family AMP-binding PF00501.23 KEZ45137.1 - 5.2e-46 156.8 0.0 4.3e-45 153.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ45137.1 - 8.4e-09 36.2 0.0 2.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glutaredoxin2_C PF04399.8 KEZ45137.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DNA_pol_E_B PF04042.11 KEZ45138.1 - 7.5e-54 182.1 0.0 1.1e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dmrt1 PF12374.3 KEZ45139.1 - 0.31 11.4 1.4 0.87 9.9 0.4 2.0 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 Methyltransf_16 PF10294.4 KEZ45140.1 - 6.8e-18 64.7 0.0 1.1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEZ45140.1 - 1.6e-08 35.0 0.0 3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEZ45140.1 - 7.8e-05 22.3 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KEZ45140.1 - 9.5e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ45140.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEZ45140.1 - 0.00046 19.4 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 KEZ45140.1 - 0.00064 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KEZ45140.1 - 0.00066 19.2 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ45140.1 - 0.0072 16.3 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KEZ45140.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.7 KEZ45140.1 - 0.026 14.9 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45140.1 - 0.054 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KEZ45140.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_S24e PF01282.14 KEZ45141.1 - 2.4e-35 120.1 0.0 4e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e MerE PF05052.7 KEZ45142.1 - 0.023 14.6 0.7 0.048 13.6 0.5 1.6 1 0 0 1 1 1 0 MerE protein SH2_2 PF14633.1 KEZ45143.1 - 3.3e-80 268.2 0.1 3.3e-80 268.2 0.0 2.3 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KEZ45143.1 - 5.3e-35 119.9 4.2 5.3e-35 119.9 2.9 4.2 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 KEZ45143.1 - 5.2e-31 106.8 0.0 1.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KEZ45143.1 - 5.9e-29 100.5 0.0 2.9e-28 98.3 0.0 2.3 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KEZ45143.1 - 8e-21 74.0 31.7 8e-21 74.0 22.0 6.2 4 1 2 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KEZ45143.1 - 2.9e-19 69.2 2.8 3e-18 65.9 1.9 2.5 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 KEZ45143.1 - 1e-05 25.5 0.7 1e-05 25.5 0.5 2.0 2 0 0 2 2 2 1 S1 RNA binding domain SH2 PF00017.19 KEZ45143.1 - 0.00047 19.8 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 KEZ45143.1 - 0.015 15.1 0.0 0.042 13.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HAD_2 PF13419.1 KEZ45144.1 - 5.8e-08 33.1 0.0 2e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ45144.1 - 3.9e-07 29.6 0.1 8.6e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEZ45144.1 - 4.1e-06 27.3 0.0 0.068 13.5 0.0 2.4 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ45144.1 - 0.003 17.7 0.1 0.012 15.7 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 KEZ45144.1 - 0.14 11.4 0.0 0.66 9.3 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Pkinase PF00069.20 KEZ45145.1 - 1.2e-60 204.8 0.0 2e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45145.1 - 9.9e-40 136.2 0.0 1.4e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ45145.1 - 8e-06 25.0 0.0 1.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DHquinase_I PF01487.10 KEZ45145.1 - 0.043 13.4 0.1 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Type I 3-dehydroquinase Choline_kinase PF01633.15 KEZ45145.1 - 0.15 11.5 0.2 0.3 10.6 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase FUSC_2 PF13515.1 KEZ45146.1 - 1.9e-22 79.5 6.5 1.9e-22 79.5 4.5 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KEZ45146.1 - 4.9e-07 28.5 20.4 6.7e-06 24.8 3.7 3.3 3 1 0 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 KEZ45146.1 - 5.6e-05 22.8 0.1 0.0085 15.7 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KEZ45146.1 - 0.032 12.9 17.9 0.3 9.7 1.9 4.2 4 0 0 4 4 4 0 Aluminium activated malate transporter DUF936 PF06075.7 KEZ45147.1 - 0.54 9.1 25.2 0.72 8.7 17.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FAM196 PF15265.1 KEZ45147.1 - 1.2 8.3 21.7 1.8 7.6 15.1 1.4 1 0 0 1 1 1 0 FAM196 family Formyl_trans_N PF00551.14 KEZ45148.1 - 1.3e-21 77.0 0.0 2.1e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KEZ45148.1 - 0.058 13.4 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Cytochrom_B561 PF03188.11 KEZ45150.1 - 2.3e-08 33.9 11.6 2.3e-08 33.9 8.1 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KEZ45150.1 - 1.7e-05 24.3 0.6 1.7e-05 24.3 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) L_HGMIC_fpl PF10242.4 KEZ45150.1 - 0.13 12.2 0.7 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein DUF2306 PF10067.4 KEZ45150.1 - 0.58 10.2 14.1 0.025 14.6 3.1 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) Cu-oxidase_3 PF07732.10 KEZ45152.1 - 4.9e-41 139.1 4.7 4.9e-41 139.1 3.2 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEZ45152.1 - 9.4e-39 132.0 2.3 9.4e-39 132.0 1.6 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KEZ45152.1 - 6.6e-34 117.1 0.1 1.4e-33 116.0 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Pkinase PF00069.20 KEZ45153.1 - 1e-26 93.6 0.0 2.2e-21 76.1 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45153.1 - 1.1e-07 31.2 0.0 0.022 13.8 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 KEZ45153.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KEZ45153.1 - 0.2 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CorA PF01544.13 KEZ45154.1 - 1.5e-05 24.1 0.2 5.1e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SNF2_N PF00176.18 KEZ45155.1 - 6.5e-11 41.5 0.1 9.5e-08 31.1 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KEZ45155.1 - 9.9e-11 41.3 0.0 7.8e-08 31.8 0.0 2.5 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 KEZ45155.1 - 2.9e-05 23.7 4.1 2.9e-05 23.7 2.9 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEZ45155.1 - 0.0025 17.7 5.2 0.0025 17.7 3.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KEZ45155.1 - 0.026 14.3 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_L44 PF00935.14 KEZ45157.1 - 1.9e-34 117.5 11.8 2.5e-34 117.0 8.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Rho_N PF07498.7 KEZ45158.1 - 0.01 15.6 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain p450 PF00067.17 KEZ45159.1 - 1.4e-48 165.6 0.0 2.9e-36 124.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 KEZ45160.1 - 1.4e-11 43.7 44.1 3.8e-11 42.3 10.3 4.3 3 1 1 4 4 4 3 Major Facilitator Superfamily Glyoxalase_2 PF12681.2 KEZ45162.1 - 3.4e-11 43.7 0.0 4.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KEZ45162.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pkinase PF00069.20 KEZ45163.1 - 1.8e-09 37.1 0.0 3.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Fungal_trans PF04082.13 KEZ45164.1 - 3.5e-24 85.0 0.0 5e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45164.1 - 0.0049 16.7 5.2 0.0082 16.0 3.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytidylate_kin PF02224.13 KEZ45165.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase Asp_protease_2 PF13650.1 KEZ45166.1 - 3.4e-05 24.2 0.0 6.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KEZ45166.1 - 0.00093 18.9 0.1 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DLIC PF05783.6 KEZ45166.1 - 0.032 12.8 0.1 0.054 12.1 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Band_7 PF01145.20 KEZ45166.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family MFS_1 PF07690.11 KEZ45167.1 - 1.2e-31 109.7 50.3 2.6e-31 108.6 34.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KEZ45168.1 - 1.4e-06 28.1 10.0 0.0082 16.4 1.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ45168.1 - 1.5e-06 28.1 12.7 0.0049 17.1 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type CTP_transf_2 PF01467.21 KEZ45169.1 - 1.7e-22 80.1 0.0 3.4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase TauD PF02668.11 KEZ45170.1 - 2.4e-21 76.5 0.0 3.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEZ45170.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 CsiD Lin-8 PF03353.10 KEZ45171.1 - 3.1 6.9 4.0 4.9 6.3 2.8 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Acetyltransf_1 PF00583.19 KEZ45172.1 - 0.00015 21.7 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ45172.1 - 0.009 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RRM_1 PF00076.17 KEZ45173.1 - 1.1e-38 130.7 0.9 3.7e-18 64.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ45173.1 - 5.9e-30 103.0 0.2 7.4e-15 54.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ45173.1 - 1.4e-12 47.2 0.3 3.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ45173.1 - 0.001 18.7 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KEZ45173.1 - 0.11 12.3 0.2 18 5.2 0.0 2.7 2 1 1 3 3 3 0 RNA binding motif RabGAP-TBC PF00566.13 KEZ45175.1 - 7.6e-47 159.5 0.0 1.7e-46 158.4 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 KEZ45176.1 - 9.4e-52 173.3 11.0 7.7e-19 67.8 0.3 4.1 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45176.1 - 9.1e-51 167.2 13.6 2e-08 33.6 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KEZ45176.1 - 4.3e-40 135.3 5.2 2.2e-10 40.7 0.1 6.8 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ45176.1 - 1.2e-37 124.1 8.8 3.6e-06 26.6 0.0 8.0 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KEZ45176.1 - 8.1e-24 83.1 4.9 9.3e-06 25.7 0.1 6.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ45176.1 - 8.4e-10 38.5 0.1 2.3e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEZ45176.1 - 0.0018 18.3 5.0 0.018 14.9 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ45176.1 - 0.0031 17.6 0.2 0.3 11.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KEZ45176.1 - 0.0096 15.6 0.0 0.046 13.4 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 KEZ45176.1 - 0.088 11.6 0.0 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain Oxysterol_BP PF01237.13 KEZ45177.1 - 6.5e-112 373.5 0.0 1.5e-111 372.3 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 KEZ45177.1 - 5.4e-37 125.7 0.6 1.3e-36 124.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KEZ45177.1 - 2.4e-05 24.4 0.0 7.8e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KEZ45177.1 - 0.00052 20.2 1.9 0.054 13.7 1.2 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain ThiF PF00899.16 KEZ45178.1 - 9.1e-29 100.0 0.0 1.5e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KEZ45178.1 - 0.043 13.9 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase dCMP_cyt_deam_1 PF00383.17 KEZ45179.1 - 4.6e-26 90.4 2.0 7.3e-26 89.7 1.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KEZ45179.1 - 0.00015 22.5 0.1 0.00042 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain CoaE PF01121.15 KEZ45179.1 - 0.0035 16.7 0.1 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 KEZ45179.1 - 0.0063 16.8 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain MRC1 PF09444.5 KEZ45180.1 - 4.5e-37 127.5 20.2 4.5e-37 127.5 14.0 7.3 6 2 1 7 7 7 1 MRC1-like domain Gln-synt_C PF00120.19 KEZ45181.1 - 4.8e-61 206.1 0.0 6e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KEZ45181.1 - 8.8e-19 66.8 0.0 1.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain APH PF01636.18 KEZ45182.1 - 2e-06 27.6 0.0 6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ45182.1 - 7.1e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 KEZ45182.1 - 0.0091 15.1 0.0 4.3 6.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain SHNi-TPR PF10516.4 KEZ45183.1 - 2.6e-16 58.5 1.1 9.2e-16 56.8 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 KEZ45183.1 - 3.7e-07 29.6 6.3 0.0001 21.9 0.4 3.0 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 KEZ45183.1 - 7.5e-07 29.0 7.7 0.0013 18.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ45183.1 - 5e-05 23.8 2.1 0.00029 21.4 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ45183.1 - 0.021 14.4 2.3 0.11 12.2 1.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEZ45183.1 - 0.022 14.9 1.2 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KEZ45183.1 - 0.048 13.5 11.8 0.11 12.4 1.7 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ45183.1 - 0.099 12.8 0.1 1.8 8.9 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ45183.1 - 3.2 7.7 7.3 9.3 6.3 0.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.7 KEZ45185.1 - 0.066 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Abhydrolase_6 PF12697.2 KEZ45187.1 - 7.8e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DnaJ PF00226.26 KEZ45188.1 - 3e-13 49.2 0.0 4.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 KEZ45189.1 - 6e-30 104.1 34.2 1.1e-29 103.3 23.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45189.1 - 1.7e-20 73.0 19.9 6.1e-18 64.6 7.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.20 KEZ45191.1 - 1.4e-11 44.0 0.0 1.3e-05 24.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45191.1 - 4.3e-05 22.7 0.0 0.0051 15.9 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pro_isomerase PF00160.16 KEZ45192.1 - 9.8e-46 155.7 0.1 1.4e-45 155.2 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KEZ45192.1 - 7.4e-15 54.3 5.4 6.9e-09 35.2 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KEZ45192.1 - 2.6e-10 39.3 4.4 3.7e-05 23.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ45192.1 - 3.6e-10 38.9 2.6 2.4e-05 23.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ45192.1 - 7.3e-08 32.2 0.5 0.00014 21.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ45192.1 - 0.00015 21.3 1.7 0.0095 15.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ45192.1 - 0.0011 19.2 1.6 0.095 13.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ45192.1 - 0.0019 18.6 8.5 0.017 15.7 0.4 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat BTAD PF03704.12 KEZ45192.1 - 0.098 12.9 3.6 0.29 11.4 0.0 2.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_16 PF13432.1 KEZ45192.1 - 0.29 11.8 16.4 0.33 11.6 0.5 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ45192.1 - 0.93 9.8 5.1 31 5.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 KEZ45193.1 - 5.4e-47 159.4 0.2 6.1e-47 159.2 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 KEZ45194.1 - 1.7e-97 325.3 29.0 2.8e-97 324.5 20.1 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KEZ45194.1 - 1.7e-41 141.2 9.8 3.7e-41 140.1 6.3 2.0 1 1 1 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.6 KEZ45194.1 - 0.0033 17.2 3.2 0.0041 16.8 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Syntaxin PF00804.20 KEZ45194.1 - 0.0059 16.7 15.7 0.047 13.8 5.3 2.6 2 0 0 2 2 2 2 Syntaxin DUF2373 PF10180.4 KEZ45194.1 - 0.0073 15.8 3.2 0.015 14.8 2.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Poty_PP PF08440.5 KEZ45194.1 - 0.0085 15.1 3.4 0.017 14.2 2.3 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein Snapin_Pallidin PF14712.1 KEZ45194.1 - 0.0089 16.3 12.2 0.41 11.0 0.4 2.6 2 0 0 2 2 2 2 Snapin/Pallidin DUF904 PF06005.7 KEZ45194.1 - 0.034 14.4 1.6 0.034 14.4 1.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Cep57_MT_bd PF06657.8 KEZ45194.1 - 0.44 10.5 11.3 0.12 12.3 1.4 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Syntaxin_2 PF14523.1 KEZ45194.1 - 0.79 9.7 11.5 0.12 12.4 2.7 2.7 1 1 2 3 3 3 0 Syntaxin-like protein CorA PF01544.13 KEZ45194.1 - 4.4 6.2 6.7 0.98 8.3 1.6 2.0 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein HypA PF01155.14 KEZ45195.1 - 0.014 15.0 1.1 0.024 14.3 0.7 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_4 PF13894.1 KEZ45195.1 - 0.045 14.1 0.5 0.045 14.1 0.3 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Iso_dh PF00180.15 KEZ45196.1 - 7.4e-72 242.1 0.0 8.7e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 KEZ45196.1 - 0.042 13.8 0.4 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) Ino80_Iec3 PF14612.1 KEZ45197.1 - 2.2e-45 155.5 5.1 2.6e-26 93.1 0.1 2.7 2 1 1 3 3 3 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling KIAA1430 PF13879.1 KEZ45197.1 - 0.18 12.2 2.5 2.5 8.5 0.0 2.6 2 0 0 2 2 2 0 KIAA1430 homologue Macoilin PF09726.4 KEZ45197.1 - 2 6.5 7.5 3.3 5.8 5.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Endosulfine PF04667.12 KEZ45198.1 - 9.7e-21 73.5 0.0 1.6e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HET PF06985.6 KEZ45199.1 - 1.9e-38 131.7 0.0 3.7e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.1 KEZ45199.1 - 7.6e-16 57.8 3.6 1.9e-08 34.1 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ45199.1 - 2.3e-10 40.0 2.7 4.9e-07 29.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF676 PF05057.9 KEZ45199.1 - 1.1e-05 24.9 0.0 2.8e-05 23.5 0.0 1.6 1 1 1 2 2 2 1 Putative serine esterase (DUF676) TPR_14 PF13428.1 KEZ45199.1 - 0.02 15.4 1.7 0.25 12.0 0.4 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat PGAP1 PF07819.8 KEZ45199.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 KEZ45199.1 - 0.049 13.3 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family TPR_19 PF14559.1 KEZ45199.1 - 0.11 12.8 2.7 0.23 11.8 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF829 PF05705.9 KEZ45199.1 - 0.14 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Lipase_3 PF01764.20 KEZ45199.1 - 0.19 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 KEZ45199.1 - 0.2 10.7 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain TPR_6 PF13174.1 KEZ45199.1 - 0.37 11.3 1.8 1 9.9 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ45199.1 - 5.3 7.0 6.3 3.8 7.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SPX PF03105.14 KEZ45201.1 - 1.4e-21 77.5 3.2 2.2e-14 53.9 0.7 3.4 2 1 1 3 3 3 2 SPX domain Chromate_transp PF02417.10 KEZ45201.1 - 0.034 13.7 2.9 0.05 13.2 2.0 1.2 1 0 0 1 1 1 0 Chromate transporter BioY PF02632.9 KEZ45201.1 - 0.24 11.0 5.1 0.21 11.2 0.8 1.9 1 1 1 2 2 2 0 BioY family Fungal_trans PF04082.13 KEZ45202.1 - 3.9e-08 32.4 0.0 6.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45202.1 - 6.4e-07 29.1 10.6 1.3e-06 28.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_Me_trans PF04252.8 KEZ45204.1 - 1.5e-46 158.2 0.0 1.7e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF2007 PF09413.5 KEZ45205.1 - 0.069 12.9 0.1 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) DUF1814 PF08843.6 KEZ45206.1 - 0.00024 20.9 0.0 0.00046 20.0 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) Fe_dep_repr_C PF02742.10 KEZ45206.1 - 0.052 13.2 0.1 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Peptidase_S10 PF00450.17 KEZ45207.1 - 2.2e-113 379.5 0.1 2.9e-113 379.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KEZ45207.1 - 0.00021 21.2 0.0 0.00069 19.5 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family CIAPIN1 PF05093.8 KEZ45208.1 - 2.1e-34 117.5 1.8 3.2e-34 117.0 1.2 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Ceramidase_alk PF04734.8 KEZ45209.1 - 2.3e-271 901.5 0.0 2.7e-271 901.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Tctex-1 PF03645.8 KEZ45210.1 - 3.6e-35 119.8 0.0 4.2e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 KEZ45211.1 - 8.8e-14 51.4 2.9 8.8e-14 51.4 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Cyt_c_ox_IV PF12270.3 KEZ45211.1 - 0.036 13.8 0.5 0.067 12.9 0.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Bax1-I PF01027.15 KEZ45211.1 - 0.054 13.0 4.2 0.075 12.6 2.9 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MARVEL PF01284.18 KEZ45211.1 - 0.5 10.1 5.9 0.97 9.2 4.1 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF2189 PF09955.4 KEZ45211.1 - 1.1 9.2 6.3 0.43 10.5 1.5 1.9 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) CFEM PF05730.6 KEZ45212.1 - 0.037 13.8 12.3 0.082 12.7 8.5 1.7 1 1 0 1 1 1 0 CFEM domain zinc-ribbons_6 PF07191.7 KEZ45212.1 - 0.92 9.3 11.0 0.33 10.7 3.6 2.2 1 1 1 2 2 2 0 zinc-ribbons RRM_1 PF00076.17 KEZ45213.1 - 4.2e-17 61.5 0.0 6.9e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ45213.1 - 2.3e-15 56.3 0.0 4.8e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ45213.1 - 6.3e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF972 PF06156.8 KEZ45213.1 - 0.011 16.1 1.3 0.015 15.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KEZ45213.1 - 0.024 12.4 1.0 0.026 12.4 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.4 KEZ45213.1 - 0.053 11.9 1.0 0.066 11.6 0.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Packaging_FI PF14000.1 KEZ45213.1 - 0.056 13.6 5.0 0.062 13.4 3.1 1.5 1 1 0 1 1 1 0 DNA packaging protein FI IncA PF04156.9 KEZ45213.1 - 0.099 12.2 1.2 0.12 12.0 0.8 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KEZ45213.1 - 0.23 10.4 2.3 0.26 10.3 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4337 PF14235.1 KEZ45213.1 - 1.1 9.0 4.7 1.6 8.5 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HECT PF00632.20 KEZ45214.1 - 3.1e-93 312.4 0.0 4.1e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KEZ45214.1 - 2.7e-32 110.2 16.6 7.9e-12 44.8 2.4 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KEZ45214.1 - 1.5e-17 63.1 0.2 5.2e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 C2 domain PurS PF02700.9 KEZ45214.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Oxidored_q6 PF01058.17 KEZ45215.1 - 3e-22 78.6 0.0 5.1e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PMI_typeI PF01238.16 KEZ45217.1 - 4.1e-135 450.5 0.0 4.7e-135 450.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I PUL PF08324.6 KEZ45217.1 - 0.05 12.3 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 PUL domain DUF1325 PF07039.6 KEZ45218.1 - 3.3e-28 97.9 0.0 5e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF1777 PF08648.7 KEZ45218.1 - 0.00029 20.6 12.1 0.00029 20.6 8.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Arf PF00025.16 KEZ45219.1 - 6.8e-76 253.3 0.1 7.8e-76 253.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KEZ45219.1 - 4.2e-13 49.0 0.0 4.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KEZ45219.1 - 1.5e-12 46.9 1.7 3.7e-09 35.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KEZ45219.1 - 9.1e-12 44.5 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KEZ45219.1 - 5.3e-11 42.1 0.0 6.2e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KEZ45219.1 - 1.5e-08 35.1 0.0 2.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEZ45219.1 - 0.00015 21.7 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEZ45219.1 - 0.00063 19.2 0.0 0.0038 16.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KEZ45219.1 - 0.0085 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DegQ PF08181.6 KEZ45219.1 - 0.025 14.3 0.2 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 DegQ (SacQ) family Pkinase PF00069.20 KEZ45220.1 - 4.5e-61 206.2 0.1 1.4e-60 204.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45220.1 - 5.5e-31 107.5 0.0 3e-30 105.1 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Zip PF02535.17 KEZ45220.1 - 0.00055 19.0 0.6 0.00066 18.7 0.4 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Kinase-like PF14531.1 KEZ45220.1 - 0.014 14.4 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Innate_immun PF12782.2 KEZ45220.1 - 9.4 5.3 12.9 15 4.6 9.0 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Actin PF00022.14 KEZ45221.1 - 1.6e-117 392.2 0.0 1.8e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEZ45221.1 - 0.015 13.9 0.0 0.095 11.2 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein LMWPc PF01451.16 KEZ45222.1 - 4.3e-36 124.2 0.0 4.9e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase PF00069.20 KEZ45223.1 - 2.3e-72 243.2 0.0 2.7e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45223.1 - 2.8e-31 108.5 0.0 3.9e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ45223.1 - 0.017 14.8 0.1 0.062 13.0 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KEZ45223.1 - 0.082 11.9 0.1 0.22 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3455 PF11937.3 KEZ45224.1 - 3.2e-20 72.8 0.1 8.2e-20 71.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3455) NmrA PF05368.8 KEZ45225.1 - 8.2e-37 126.6 0.0 1.3e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ45225.1 - 9.3e-14 51.8 0.2 1.5e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ45225.1 - 0.00015 20.6 0.0 0.00023 19.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KEZ45225.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KEZ45225.1 - 0.058 13.0 0.2 0.058 13.0 0.1 2.0 3 0 0 3 3 3 0 KR domain DXP_reductoisom PF02670.11 KEZ45225.1 - 0.069 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF1199 PF06712.6 KEZ45225.1 - 0.085 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Hexapep PF00132.19 KEZ45226.1 - 3.6e-08 32.5 5.1 2.4e-05 23.6 2.3 4.0 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KEZ45226.1 - 6e-06 25.7 4.6 0.0022 17.5 0.3 2.8 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF1279 PF06916.8 KEZ45227.1 - 6.1e-27 93.7 0.1 1e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) TFR_dimer PF04253.10 KEZ45228.1 - 0.031 13.8 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain eIF-5_eIF-2B PF01873.12 KEZ45229.1 - 8.1e-46 154.7 0.5 1.3e-45 154.0 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 MYT1 PF08474.6 KEZ45229.1 - 0.044 13.2 2.0 4.1 6.8 0.1 2.3 1 1 1 2 2 2 0 Myelin transcription factor 1 Lar_restr_allev PF14354.1 KEZ45229.1 - 0.048 13.9 0.2 0.15 12.3 0.1 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar Med19 PF10278.4 KEZ45229.1 - 0.09 12.4 6.3 0.2 11.3 4.4 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Arc_trans_TRASH PF08394.5 KEZ45229.1 - 0.98 9.6 6.9 1.7 8.8 0.1 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain DAO PF01266.19 KEZ45230.1 - 3.7e-51 174.1 2.6 4.5e-51 173.8 1.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ45230.1 - 9.5e-05 22.3 0.5 0.00025 20.9 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ45230.1 - 0.00033 19.6 1.6 0.00061 18.7 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEZ45230.1 - 0.016 14.3 0.4 0.046 12.7 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 KEZ45230.1 - 0.017 15.0 0.1 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ45230.1 - 0.017 14.2 0.2 0.024 13.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ45230.1 - 0.13 10.6 1.5 0.3 9.5 1.1 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KEZ45230.1 - 0.17 10.8 1.6 0.3 10.0 1.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.20 KEZ45231.1 - 1.4e-75 253.7 0.0 1.9e-75 253.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45231.1 - 1.4e-36 125.8 0.0 2.6e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KEZ45231.1 - 9.1e-17 60.9 0.5 1.9e-16 59.9 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KEZ45231.1 - 1.2e-06 27.7 0.0 2.7e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KEZ45231.1 - 0.00015 21.1 0.3 0.00042 19.7 0.2 1.7 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KEZ45231.1 - 0.0017 16.9 0.0 0.0026 16.3 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 KEZ45231.1 - 0.018 14.7 1.3 0.34 10.6 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family NmrA PF05368.8 KEZ45232.1 - 1.2e-26 93.3 0.1 1.5e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ45232.1 - 9.1e-09 35.5 0.1 4.8e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KEZ45232.1 - 8.8e-07 28.5 0.1 0.00026 20.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEZ45232.1 - 1.4e-05 23.9 0.0 1.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KEZ45232.1 - 0.00023 20.8 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KEZ45232.1 - 0.00024 21.0 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KEZ45232.1 - 0.00065 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KEZ45232.1 - 0.0083 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 KEZ45232.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_33 PF10017.4 KEZ45232.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DapB_N PF01113.15 KEZ45232.1 - 0.087 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cas_Cas02710 PF09670.5 KEZ45232.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Sugar_tr PF00083.19 KEZ45233.1 - 8.7e-81 271.7 25.8 1e-79 268.2 17.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45233.1 - 5.2e-25 87.9 25.9 5.2e-25 87.9 17.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ45233.1 - 2.2e-09 36.0 1.6 2.2e-09 36.0 1.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Trehalase PF01204.13 KEZ45235.1 - 1.2e-178 594.8 0.1 1.6e-178 594.5 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KEZ45235.1 - 8.2e-09 34.6 0.4 1.4e-08 33.9 0.3 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 KEZ45236.1 - 1e-282 938.0 2.9 1.1e-282 937.8 2.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KEZ45236.1 - 2.5e-12 46.5 0.8 2.1e-11 43.5 0.2 2.3 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF1712 PF08217.6 KEZ45237.1 - 4.9e-13 48.2 0.0 3.3e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) ApoLp-III PF07464.6 KEZ45238.1 - 0.027 14.5 5.4 0.053 13.5 3.7 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.8 KEZ45238.1 - 5 7.6 14.2 2.9 8.3 1.5 3.2 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.13 KEZ45238.1 - 7.4 6.3 14.6 0.18 11.5 4.9 2.1 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) Ribosomal_L17 PF01196.14 KEZ45239.1 - 3.2e-29 101.3 1.4 3.8e-29 101.1 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 BBP1_C PF15272.1 KEZ45239.1 - 0.056 12.9 0.1 0.077 12.5 0.1 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF1253 PF06862.7 KEZ45240.1 - 1.2e-161 538.0 0.0 1.5e-161 537.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) SUZ PF12752.2 KEZ45241.1 - 3.6e-14 53.0 5.1 3.6e-14 53.0 3.5 2.8 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 KEZ45241.1 - 2.4e-08 33.5 0.0 5.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain LRS4 PF10422.4 KEZ45242.1 - 0.39 10.0 3.3 0.33 10.2 1.2 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 TGF_beta_GS PF08515.7 KEZ45242.1 - 1.1 8.6 9.6 4.2 6.7 0.2 2.7 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif NAD_binding_5 PF07994.7 KEZ45243.1 - 1.2e-114 382.7 0.2 1.6e-114 382.3 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KEZ45243.1 - 1.2e-45 153.8 0.4 2.7e-45 152.7 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.17 KEZ45244.1 - 5.8e-23 80.7 18.1 8e-12 45.0 3.2 3.0 3 0 0 3 3 3 2 LIM domain YhfH PF14149.1 KEZ45244.1 - 4.7 7.0 10.2 14 5.5 0.0 4.1 4 0 0 4 4 4 0 YhfH-like protein PC4 PF02229.11 KEZ45245.1 - 4.2e-22 77.1 0.2 1.2e-21 75.7 0.2 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) MFS_1 PF07690.11 KEZ45246.1 - 1.7e-20 73.0 18.4 8.1e-13 47.8 5.4 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45246.1 - 2.4e-11 42.9 6.0 2.4e-11 42.9 4.1 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter 4HBT_2 PF13279.1 KEZ45247.1 - 8.8e-05 22.9 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Hydantoinase_B PF02538.9 KEZ45248.1 - 2.7e-198 659.5 0.0 3.4e-198 659.1 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KEZ45248.1 - 7.7e-72 241.8 0.0 1.7e-53 181.6 0.0 2.6 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEZ45248.1 - 1.4e-57 194.0 0.0 2.5e-57 193.1 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region GCS PF03074.11 KEZ45250.1 - 1.4e-150 501.4 0.0 9.5e-150 498.7 0.0 1.9 1 1 0 1 1 1 1 Glutamate-cysteine ligase HET PF06985.6 KEZ45251.1 - 7.5e-22 77.9 0.0 1.9e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyclin PF08613.6 KEZ45252.1 - 1.2e-13 51.7 0.1 2.1e-13 50.9 0.1 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEZ45252.1 - 0.0024 17.4 0.2 0.0038 16.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs3p PF12271.3 KEZ45253.1 - 2e-139 463.5 17.2 2.3e-139 463.3 11.9 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KEZ45253.1 - 1.4 8.8 10.6 0.031 14.1 1.2 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) DUF3716 PF12511.3 KEZ45254.1 - 4.6e-12 45.3 4.0 8.7e-12 44.4 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3138 PF11336.3 KEZ45254.1 - 0.14 10.3 0.4 0.21 9.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LTXXQ PF07813.7 KEZ45254.1 - 3.3 8.2 12.8 0.61 10.5 3.4 2.6 2 0 0 2 2 2 0 LTXXQ motif family protein Glyco_hydro_47 PF01532.15 KEZ45255.1 - 4.6e-160 533.1 0.0 5.5e-160 532.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 KEZ45255.1 - 0.046 12.7 1.0 5.9 5.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 PX PF00787.19 KEZ45258.1 - 1.1e-18 67.0 0.2 2e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 PX domain Ribosomal_L18e PF00828.14 KEZ45259.1 - 7e-19 68.4 0.1 1.2e-18 67.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Lactonase PF10282.4 KEZ45260.1 - 2.5e-52 178.1 0.0 3.2e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 KEZ45260.1 - 0.014 13.7 0.0 2.9 6.0 0.0 2.4 2 1 1 3 3 3 0 Cytochrome D1 heme domain Glyco_hydro_16 PF00722.16 KEZ45261.1 - 1.4e-42 145.0 9.4 2.2e-42 144.4 6.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KEZ45261.1 - 0.027 14.4 12.0 0.069 13.1 8.3 1.6 1 0 0 1 1 1 0 Chitin recognition protein PET PF06297.9 KEZ45261.1 - 0.099 12.3 0.0 0.31 10.6 0.0 1.9 1 0 0 1 1 1 0 PET Domain Myb_DNA-binding PF00249.26 KEZ45262.1 - 8.1e-13 48.2 2.5 7.3e-07 29.1 0.6 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEZ45262.1 - 5.7e-11 42.3 1.4 3.7e-05 23.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 KEZ45262.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_2 PF08914.6 KEZ45262.1 - 0.079 12.7 0.4 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_6 PF13921.1 KEZ45263.1 - 3.6e-05 23.7 0.1 0.0011 19.0 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KEZ45263.1 - 0.017 15.1 1.5 0.035 14.1 0.5 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain ILVD_EDD PF00920.16 KEZ45264.1 - 2.6e-198 659.7 0.3 3e-198 659.5 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.11 KEZ45265.1 - 3.3e-128 427.2 0.9 4.2e-128 426.9 0.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5B PF01215.14 KEZ45266.1 - 1e-43 148.3 0.0 1.3e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.5 KEZ45266.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc ribbon domain 4HBT_3 PF13622.1 KEZ45267.1 - 7.5e-37 127.4 3.1 8.6e-37 127.2 2.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Cullin_binding PF03556.10 KEZ45268.1 - 4.5e-33 113.8 1.6 6.6e-33 113.3 1.1 1.2 1 0 0 1 1 1 1 Cullin binding Ribosomal_S6 PF01250.12 KEZ45269.1 - 7.7e-09 35.2 0.0 9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 SQS_PSY PF00494.14 KEZ45270.1 - 4.6e-50 170.3 0.3 5.8e-50 170.0 0.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 KEZ45271.1 - 2e-72 243.5 0.0 3.3e-72 242.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KEZ45271.1 - 4.3e-25 87.7 0.0 7.7e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KEZ45271.1 - 2.9e-14 52.6 0.0 6.4e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KEZ45271.1 - 3.8e-06 26.8 10.7 8.2e-06 25.7 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ45271.1 - 2e-05 24.1 11.2 3.9e-05 23.2 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KEZ45271.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 KEZ45271.1 - 0.00056 19.5 9.2 0.0011 18.6 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.1 KEZ45271.1 - 0.005 16.3 0.1 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain zf-RING_2 PF13639.1 KEZ45271.1 - 0.0094 15.7 9.9 0.02 14.7 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KEZ45271.1 - 0.024 14.3 9.1 0.055 13.1 6.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PAT1 PF09770.4 KEZ45273.1 - 3.8 5.6 4.9 4.4 5.4 3.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_capsid PF06112.6 KEZ45273.1 - 4.8 7.2 11.8 6.9 6.7 8.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Retinal PF15449.1 KEZ45273.1 - 4.8 4.6 16.1 6.1 4.3 11.2 1.1 1 0 0 1 1 1 0 Retinal protein Asp PF00026.18 KEZ45274.1 - 4.4e-51 174.0 0.0 5.5e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ45274.1 - 6.8e-08 32.6 0.0 2.4e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Fungal_trans PF04082.13 KEZ45275.1 - 1.2e-18 66.9 0.1 2.3e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEZ45275.1 - 5.8e-09 35.7 13.2 0.00027 21.1 1.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEZ45275.1 - 3e-05 24.0 6.6 3e-05 24.0 4.6 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEZ45275.1 - 0.00037 20.6 14.3 0.054 13.8 2.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KEZ45275.1 - 1.1 9.5 5.3 0.23 11.6 0.9 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GTP_EFTU PF00009.22 KEZ45276.1 - 8.2e-21 74.2 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KEZ45276.1 - 2e-15 56.7 0.1 4e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KEZ45276.1 - 4.2e-10 39.5 2.2 1.3e-09 38.0 1.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KEZ45276.1 - 0.001 18.6 0.7 0.0029 17.2 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 KEZ45276.1 - 0.0011 18.4 0.2 0.67 9.4 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KEZ45276.1 - 0.0052 17.2 0.4 0.046 14.2 0.3 2.3 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KEZ45276.1 - 0.0055 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ45276.1 - 0.018 14.2 0.1 0.04 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEZ45276.1 - 0.049 13.4 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Dynamin family Arrestin_C PF02752.17 KEZ45277.1 - 2.2e-18 66.6 0.2 6.9e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KEZ45277.1 - 1.3e-07 31.5 0.2 0.00027 20.7 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain TFIIA PF03153.8 KEZ45277.1 - 0.08 12.8 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 KEZ45277.1 - 0.45 9.7 2.9 0.67 9.1 2.0 1.1 1 0 0 1 1 1 0 NOA36 protein LSM PF01423.17 KEZ45278.1 - 5.9e-17 60.9 0.1 8.3e-17 60.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain PIG-L PF02585.12 KEZ45279.1 - 3.1e-25 89.1 0.0 4.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SlyX PF04102.7 KEZ45281.1 - 0.041 14.2 2.6 0.051 13.9 0.4 2.2 2 0 0 2 2 2 0 SlyX Sigma70_ner PF04546.8 KEZ45282.1 - 0.0044 16.6 1.7 0.006 16.2 1.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region ApoO PF09769.4 KEZ45282.1 - 0.078 12.6 1.4 0.48 10.1 0.9 2.0 1 1 0 1 1 1 0 Apolipoprotein O MIF4G_like_2 PF09090.6 KEZ45282.1 - 0.09 11.9 0.4 0.099 11.8 0.2 1.2 1 0 0 1 1 1 0 MIF4G like Prefoldin_2 PF01920.15 KEZ45282.1 - 0.12 12.1 1.7 0.2 11.4 0.1 2.0 2 1 0 2 2 2 0 Prefoldin subunit Inhibitor_I53 PF11714.3 KEZ45282.1 - 0.13 12.2 0.8 7.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor Madanin COG2 PF06148.6 KEZ45282.1 - 0.15 11.9 2.4 0.16 11.8 0.6 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3292 PF11696.3 KEZ45282.1 - 0.17 9.6 1.4 0.66 7.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) DUF3391 PF11871.3 KEZ45282.1 - 1.3 9.1 6.7 9.3 6.4 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) DUF3549 PF12069.3 KEZ45283.1 - 0.014 14.1 0.4 0.015 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) ARGLU PF15346.1 KEZ45283.1 - 0.018 14.7 2.8 0.028 14.1 1.9 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Pro-rich_19 PF15455.1 KEZ45283.1 - 0.021 13.8 1.4 0.029 13.4 1.0 1.2 1 0 0 1 1 1 0 Proline-rich 19 DUF3287 PF11690.3 KEZ45283.1 - 0.032 14.3 0.1 0.037 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF2863 PF11062.3 KEZ45283.1 - 0.044 11.8 0.4 0.055 11.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) TT_ORF2 PF02957.10 KEZ45283.1 - 0.054 14.1 0.0 0.067 13.9 0.0 1.1 1 0 0 1 1 1 0 TT viral ORF2 Resolvase PF00239.16 KEZ45283.1 - 0.094 12.5 1.9 0.25 11.2 1.3 1.8 1 1 0 1 1 1 0 Resolvase, N terminal domain DUF2094 PF09867.4 KEZ45284.1 - 0.077 12.8 0.2 3.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2094) Nha1_C PF08619.5 KEZ45285.1 - 1.2e-70 239.0 22.0 1.4e-70 238.7 15.3 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 KEZ45285.1 - 2.4e-70 236.9 21.3 2.9e-70 236.7 14.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KEZ45285.1 - 0.033 14.1 3.0 0.06 13.3 0.2 2.5 2 0 0 2 2 2 0 YrhC-like protein FlgD_ig PF13860.1 KEZ45285.1 - 0.1 12.3 0.1 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 FlgD Ig-like domain Serglycin PF04360.7 KEZ45286.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 Serglycin FAD_binding_4 PF01565.18 KEZ45288.1 - 2.1e-20 72.6 0.5 3.7e-20 71.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ45288.1 - 2.5e-07 30.4 0.8 5e-07 29.5 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like Tom22 PF04281.8 KEZ45290.1 - 1.5e-41 141.1 0.1 2.4e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CPSF_A PF03178.10 KEZ45292.1 - 4.4e-101 338.1 0.0 1.5e-100 336.4 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KEZ45292.1 - 1.7e-63 214.5 0.0 2.5e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lactonase PF10282.4 KEZ45292.1 - 0.017 14.2 0.0 2.5 7.0 0.0 3.3 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 KEZ45292.1 - 0.04 13.8 0.1 0.15 11.9 0.1 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat PP2C PF00481.16 KEZ45293.1 - 3.4e-66 223.2 0.0 1.6e-52 178.4 0.1 2.4 1 1 1 2 2 2 2 Protein phosphatase 2C Macoilin PF09726.4 KEZ45293.1 - 1.6 6.8 10.6 2.6 6.2 7.4 1.5 1 0 0 1 1 1 0 Transmembrane protein Snf7 PF03357.16 KEZ45294.1 - 5.8e-36 123.4 17.0 5.8e-36 123.4 11.8 1.4 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 KEZ45294.1 - 0.0089 13.9 1.9 0.01 13.7 1.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HSCB_C PF07743.8 KEZ45294.1 - 0.03 14.7 1.6 0.03 14.7 1.1 3.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain CaMBD PF02888.11 KEZ45294.1 - 0.93 9.3 6.9 0.18 11.6 1.6 2.0 1 1 1 2 2 2 0 Calmodulin binding domain Ist1 PF03398.9 KEZ45294.1 - 1.4 8.3 7.2 2.9 7.2 5.0 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF4407 PF14362.1 KEZ45294.1 - 1.9 7.3 7.0 3.5 6.4 2.7 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 KEZ45294.1 - 2 6.7 7.9 2.1 6.6 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Cep57_CLD_2 PF14197.1 KEZ45294.1 - 3 7.8 7.9 3.3 7.7 1.2 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Dynamin_N PF00350.18 KEZ45295.1 - 1.1e-17 64.3 0.0 3.3e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KEZ45295.1 - 5.5e-09 35.9 0.0 2.5e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEZ45295.1 - 5.4e-06 25.9 1.1 4.8e-05 22.8 0.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 KEZ45295.1 - 0.019 13.7 0.0 0.039 12.7 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 KEZ45295.1 - 0.035 14.4 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FlgN PF05130.7 KEZ45295.1 - 0.062 13.5 1.8 0.18 12.0 1.2 1.8 1 0 0 1 1 1 0 FlgN protein Miro PF08477.8 KEZ45295.1 - 0.067 13.6 0.0 0.68 10.4 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KEZ45295.1 - 0.069 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ45295.1 - 0.089 13.6 0.0 0.31 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KEZ45296.1 - 1.3e-47 157.9 25.6 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KEZ45296.1 - 3e-05 23.8 0.0 0.025 14.2 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 KEZ45296.1 - 0.081 12.1 0.9 0.12 11.5 0.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 GrpE PF01025.14 KEZ45296.1 - 0.11 12.0 1.4 0.16 11.4 1.0 1.2 1 0 0 1 1 1 0 GrpE Phosducin PF02114.11 KEZ45297.1 - 9.5e-10 37.6 0.0 8.8e-09 34.4 0.0 2.2 1 1 0 1 1 1 1 Phosducin Ran_BP1 PF00638.13 KEZ45298.1 - 1.3e-49 167.2 2.5 2.5e-49 166.3 1.7 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KEZ45298.1 - 0.0026 17.4 0.3 0.01 15.5 0.2 1.8 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 KEZ45298.1 - 0.015 14.8 1.5 0.016 14.7 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1681) PS-DH PF14765.1 KEZ45298.1 - 0.052 12.6 0.3 0.09 11.9 0.2 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase YEATS PF03366.11 KEZ45299.1 - 8.6e-24 83.0 0.4 1.9e-23 81.9 0.1 1.8 2 0 0 2 2 2 1 YEATS family Zn_clus PF00172.13 KEZ45300.1 - 3e-07 30.2 11.9 4.6e-07 29.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ETAA1 PF15350.1 KEZ45300.1 - 1.7 6.5 1.9 2.5 6.0 1.3 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue AMP-binding PF00501.23 KEZ45301.1 - 1.2e-47 162.2 0.0 1.6e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ45301.1 - 2e-06 28.6 0.0 6.6e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAM_2 PF07647.12 KEZ45302.1 - 5.1e-16 58.2 0.0 1.1e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KEZ45302.1 - 3.3e-14 53.1 0.0 7.1e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 KEZ45302.1 - 3.3e-13 49.5 0.0 6.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Syndecan PF01034.15 KEZ45303.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Pyr_redox_2 PF07992.9 KEZ45304.1 - 7.1e-27 94.6 0.0 1.3e-25 90.4 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ45304.1 - 8.9e-16 58.0 0.0 3.4e-13 49.7 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ45304.1 - 0.0038 17.2 0.8 1.7 8.6 0.1 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SH3_1 PF00018.23 KEZ45305.1 - 0.00025 20.3 0.0 0.00063 19.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ45305.1 - 0.0064 16.0 0.0 0.019 14.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain ELFV_dehydrog PF00208.16 KEZ45307.1 - 1.2e-58 198.6 0.0 1.9e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KEZ45307.1 - 1.4e-20 72.4 0.0 2.2e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KEZ45307.1 - 1.3e-05 24.7 0.0 5.8e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.14 KEZ45308.1 - 2.9e-07 29.5 0.0 7.3e-06 24.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KEZ45308.1 - 0.0017 16.7 0.0 0.0025 16.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KEZ45308.1 - 0.0052 15.8 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.14 KEZ45308.1 - 0.17 10.2 0.0 0.35 9.1 0.0 1.4 2 0 0 2 2 2 0 Serine hydroxymethyltransferase Bac_rhamnosid PF05592.6 KEZ45309.1 - 1.5e-41 142.2 0.0 5e-40 137.1 0.0 2.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KEZ45309.1 - 1e-06 27.7 0.3 1.8e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KEZ45309.1 - 4.9e-06 25.5 0.0 7.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Ribosomal_L32e PF01655.13 KEZ45310.1 - 3.6e-49 165.3 1.1 7.6e-49 164.3 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.26 KEZ45310.1 - 3.1e-25 87.6 3.9 6.1e-25 86.7 2.7 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KEZ45310.1 - 9e-18 63.9 0.7 3.9e-16 58.7 0.0 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KEZ45310.1 - 3.2e-14 52.7 16.2 5.4e-14 51.9 11.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KEZ45310.1 - 0.0019 17.8 7.3 0.23 11.1 0.7 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 KEZ45310.1 - 3.3 8.1 10.4 12 6.3 7.2 2.0 1 1 0 1 1 1 0 Cytochrome c3 tRNA-synt_1c PF00749.16 KEZ45311.1 - 4.6e-62 209.4 0.0 8.8e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HET PF06985.6 KEZ45311.1 - 2.3e-32 112.0 0.5 5.7e-32 110.7 0.4 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_11 PF13414.1 KEZ45312.1 - 2.2e-21 75.2 10.3 1.9e-11 43.4 0.1 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KEZ45312.1 - 1.4e-16 59.3 8.5 1.3e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ45312.1 - 1.5e-15 55.7 8.7 1.7e-06 27.4 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ45312.1 - 1.2e-11 43.5 3.5 3e-05 23.4 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ45312.1 - 1.4e-09 37.7 7.0 4e-06 26.6 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ45312.1 - 5.9e-09 35.0 0.4 4.8e-07 29.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ45312.1 - 7.6e-09 35.4 0.9 0.13 12.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 KEZ45312.1 - 1.7e-07 30.7 0.2 3.1e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 KEZ45312.1 - 1.9e-07 30.7 0.5 0.0045 17.0 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ45312.1 - 2.5e-05 24.0 0.4 0.28 11.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ45312.1 - 5e-05 23.8 0.9 0.0013 19.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ45312.1 - 0.00044 20.6 0.2 0.021 15.4 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KEZ45312.1 - 0.023 14.8 3.0 0.071 13.2 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KEZ45312.1 - 0.024 14.5 1.5 5.4 7.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ45312.1 - 0.024 14.9 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 KEZ45312.1 - 0.036 12.6 0.1 0.066 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_4 PF07721.9 KEZ45312.1 - 0.073 13.5 0.1 35 5.2 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat HMA PF00403.21 KEZ45313.1 - 2.4e-12 46.8 0.0 4.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 KEZ45313.1 - 5.3e-12 46.0 0.0 8.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.13 KEZ45314.1 - 2.2e-36 124.7 0.0 3.1e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 KEZ45315.1 - 3.1e-81 270.2 1.1 5.4e-44 149.6 0.2 2.0 2 0 0 2 2 2 2 Uricase HET PF06985.6 KEZ45316.1 - 8.3e-18 64.8 0.0 1.4e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PDH PF02153.12 KEZ45317.1 - 3.6e-12 45.7 0.0 5.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KEZ45317.1 - 9e-07 28.8 0.1 2e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEZ45317.1 - 2.6e-06 27.7 0.1 5.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KEZ45317.1 - 0.00017 20.7 0.0 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KEZ45317.1 - 0.002 17.6 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KEZ45317.1 - 0.0059 16.6 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 KEZ45317.1 - 0.0083 15.8 0.0 0.02 14.5 0.0 1.6 1 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KEZ45317.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.4 KEZ45317.1 - 0.085 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain Mpv17_PMP22 PF04117.7 KEZ45318.1 - 4.9e-13 48.5 3.0 1.9e-12 46.5 1.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Phos_pyr_kin PF08543.7 KEZ45319.1 - 2.6e-73 246.2 0.9 3.6e-73 245.8 0.6 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KEZ45319.1 - 3.6e-48 164.0 0.1 5.5e-48 163.4 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KEZ45319.1 - 5.1e-09 35.6 0.1 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 KEZ45319.1 - 0.0034 16.5 0.6 0.22 10.6 0.0 2.2 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 KEZ45319.1 - 0.0054 16.0 0.7 0.077 12.2 0.1 2.3 2 0 0 2 2 2 1 Carbohydrate kinase CbiK PF06180.6 KEZ45319.1 - 0.028 13.5 0.1 0.08 12.0 0.1 1.7 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DEAD PF00270.24 KEZ45320.1 - 2.4e-45 154.0 0.0 1.4e-43 148.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ45320.1 - 6.2e-22 77.2 0.1 2.8e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ45320.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GRP PF07172.6 KEZ45320.1 - 0.017 15.5 1.7 0.017 15.5 1.2 3.4 2 1 1 3 3 3 0 Glycine rich protein family Glyoxalase_3 PF13468.1 KEZ45320.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain Helicase_C_2 PF13307.1 KEZ45320.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Catalase-rel PF06628.7 KEZ45320.1 - 0.13 12.0 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive DUF1253 PF06862.7 KEZ45320.1 - 0.22 9.9 0.0 11 4.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) APC_CDC26 PF10471.4 KEZ45321.1 - 3.3 8.4 10.7 0.88 10.3 3.2 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 FAM165 PF14981.1 KEZ45321.1 - 6.8 6.2 8.9 11 5.5 6.2 1.3 1 0 0 1 1 1 0 FAM165 family DUF1682 PF07946.9 KEZ45321.1 - 6.9 5.4 7.2 9 5.0 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ribosomal_S9 PF00380.14 KEZ45322.1 - 2e-32 111.9 0.5 1.3e-31 109.3 0.4 1.9 1 1 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 KEZ45322.1 - 0.063 10.7 0.0 0.078 10.4 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein RICTOR_N PF14664.1 KEZ45323.1 - 3.6e-98 328.5 0.1 3.2e-94 315.5 0.0 2.8 2 1 1 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KEZ45323.1 - 2.8e-87 291.4 0.0 3.9e-86 287.7 0.0 2.6 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KEZ45323.1 - 1e-41 141.4 0.0 1.1e-40 138.2 0.0 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KEZ45323.1 - 1e-27 95.8 0.5 2.5e-25 88.1 0.0 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KEZ45323.1 - 5.6e-15 54.8 9.9 1.3e-14 53.6 6.9 1.7 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.4 KEZ45323.1 - 8.8e-06 24.2 0.7 0.018 13.3 0.0 3.7 4 0 0 4 4 4 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 KEZ45323.1 - 7.8e-05 22.8 1.8 2.9 8.2 0.4 5.3 4 1 0 4 4 4 1 HEAT repeats Uds1 PF15456.1 KEZ45323.1 - 0.00046 20.1 7.0 0.0012 18.8 4.9 1.6 1 0 0 1 1 1 1 Up-regulated During Septation IncA PF04156.9 KEZ45323.1 - 0.046 13.3 4.0 0.084 12.4 2.8 1.4 1 0 0 1 1 1 0 IncA protein Rad9 PF04139.8 KEZ45324.1 - 1.9e-37 128.7 0.0 2.5e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Rad9 Alk_phosphatase PF00245.15 KEZ45325.1 - 1.2e-106 356.9 0.0 1.6e-106 356.5 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KEZ45325.1 - 0.00018 20.9 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Spore_GerAC PF05504.6 KEZ45325.1 - 0.041 13.6 0.0 0.66 9.7 0.0 2.1 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Abhydrolase_6 PF12697.2 KEZ45326.1 - 2.3e-23 83.2 0.0 4.2e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ45326.1 - 3.6e-15 55.9 0.0 1.9e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ45326.1 - 7.6e-14 51.8 0.0 4e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 KEZ45326.1 - 9.4e-10 38.1 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PGAP1 PF07819.8 KEZ45326.1 - 2.3e-05 24.1 0.2 0.00017 21.2 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein PTPlike_phytase PF14566.1 KEZ45326.1 - 0.00024 21.1 0.6 0.00071 19.6 0.0 2.0 3 0 0 3 3 2 1 Inositol hexakisphosphate Thioesterase PF00975.15 KEZ45326.1 - 0.00025 21.3 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Y_phosphatase PF00102.22 KEZ45326.1 - 0.0022 17.3 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LCAT PF02450.10 KEZ45326.1 - 0.0047 15.9 0.0 0.0072 15.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 KEZ45326.1 - 0.0058 15.9 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PAF-AH_p_II PF03403.8 KEZ45326.1 - 0.013 13.8 0.1 2.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF2305 PF10230.4 KEZ45326.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 KEZ45326.1 - 0.036 13.6 0.1 0.1 12.2 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.8 KEZ45326.1 - 0.047 13.3 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase DUF676 PF05057.9 KEZ45326.1 - 0.056 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF1749 PF08538.5 KEZ45326.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 KEZ45326.1 - 0.087 12.2 0.0 2.6 7.4 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase VirJ PF06057.6 KEZ45326.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Hydrolase_4 PF12146.3 KEZ45326.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Ribosomal_L34e PF01199.13 KEZ45327.1 - 5e-32 109.9 1.8 1.1e-31 108.8 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L34e Zn_ribbon_recom PF13408.1 KEZ45327.1 - 0.078 13.2 0.5 0.24 11.6 0.2 1.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF1428 PF07237.6 KEZ45327.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Ricin_B_lectin PF00652.17 KEZ45328.1 - 2.7e-16 59.7 0.8 3.1e-07 30.4 0.1 4.3 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain DYW_deaminase PF14432.1 KEZ45329.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Ribosomal_S19e PF01090.14 KEZ45330.1 - 1.4e-58 196.2 0.3 1.6e-58 196.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_45 PF14947.1 KEZ45330.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DUF3722 PF12519.3 KEZ45331.1 - 1.1e-82 277.1 0.0 1.8e-82 276.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 KEZ45331.1 - 0.015 14.6 0.1 0.027 13.7 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic porin PAP2_3 PF14378.1 KEZ45332.1 - 2.9e-23 82.3 13.5 3.7e-18 65.7 3.1 3.0 3 1 0 3 3 3 2 PAP2 superfamily Mid2 PF04478.7 KEZ45332.1 - 0.18 11.1 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor PAP2 PF01569.16 KEZ45332.1 - 5.1 6.7 14.6 0.51 10.0 5.4 2.4 2 1 1 3 3 3 0 PAP2 superfamily LDB19 PF13002.2 KEZ45333.1 - 9.5e-35 119.8 0.1 1.3e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 KEZ45333.1 - 0.038 13.8 0.1 0.22 11.3 0.0 2.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DUF4449 PF14613.1 KEZ45334.1 - 4.1e-47 160.1 0.9 4.1e-47 160.1 0.6 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) UPRTase PF14681.1 KEZ45335.1 - 4.6e-70 235.0 0.0 5.2e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KEZ45335.1 - 2.5e-06 27.2 0.0 6e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 KEZ45335.1 - 0.0021 17.2 0.3 0.052 12.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI PRTase_2 PF15609.1 KEZ45335.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase DNA_ligase_A_M PF01068.16 KEZ45336.1 - 1.9e-41 141.6 0.0 3.8e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KEZ45336.1 - 1.2e-36 126.1 0.0 2.4e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KEZ45336.1 - 9.9e-17 61.1 0.5 2.8e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KEZ45336.1 - 1.3e-09 38.0 0.0 7.5e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 KEZ45336.1 - 0.0019 17.9 0.0 0.06 13.0 0.0 2.3 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.3 KEZ45336.1 - 0.0086 15.7 0.4 0.04 13.6 0.0 2.3 3 0 0 3 3 3 1 DNA ligase IV LigB PF02900.13 KEZ45337.1 - 1.3e-43 149.0 0.1 3.9e-43 147.4 0.0 1.9 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Amidohydro_5 PF13594.1 KEZ45337.1 - 1.5e-10 40.6 0.4 3.8e-06 26.6 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_4 PF13147.1 KEZ45337.1 - 3.3e-10 40.4 8.3 4.6e-09 36.7 1.3 3.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KEZ45337.1 - 1.1e-07 31.8 0.1 1.7e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 KEZ45337.1 - 0.00026 20.3 0.3 0.00055 19.2 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family GST_C_3 PF14497.1 KEZ45338.1 - 3.4e-11 43.5 0.0 4.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEZ45338.1 - 8.8e-07 28.8 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEZ45338.1 - 5.8e-05 23.1 0.0 0.0004 20.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ45338.1 - 0.0096 16.1 0.0 0.025 14.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ45338.1 - 0.011 15.5 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MAP65_ASE1 PF03999.7 KEZ45339.1 - 7.3e-81 272.6 7.2 8.1e-81 272.4 1.3 2.0 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) AAA_13 PF13166.1 KEZ45339.1 - 0.058 11.8 6.1 0.012 14.1 0.7 1.9 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.4 KEZ45339.1 - 0.22 11.7 6.4 2.2 8.4 0.0 3.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 KEZ45339.1 - 0.81 9.5 2.6 9.8 6.1 0.3 3.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Peptidase_M28 PF04389.12 KEZ45340.1 - 1.9e-37 128.6 0.0 2.9e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEZ45340.1 - 1.3e-15 56.8 0.1 3.7e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 KEZ45340.1 - 6.3e-05 22.5 0.0 9.4e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GMC_oxred_N PF00732.14 KEZ45341.1 - 1.1e-47 162.6 0.0 1.6e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ45341.1 - 5.8e-25 88.2 0.0 1.9e-24 86.6 0.0 1.9 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ45341.1 - 0.0011 17.9 0.0 0.0035 16.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ45341.1 - 0.0078 16.2 0.1 0.12 12.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KEZ45341.1 - 0.014 15.4 0.5 0.055 13.4 0.2 2.1 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.1 KEZ45341.1 - 0.023 14.6 0.1 0.071 13.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KEZ45341.1 - 0.043 12.9 0.1 0.073 12.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KEZ45341.1 - 0.043 12.6 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KEZ45341.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DOT1 PF08123.8 KEZ45342.1 - 7.2e-76 254.0 0.0 1.1e-75 253.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KEZ45342.1 - 9e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45342.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45342.1 - 0.0064 17.0 0.1 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ45342.1 - 0.052 12.9 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DUF2464 PF10240.4 KEZ45342.1 - 2.1 7.6 6.0 3.4 6.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) ATG16 PF08614.6 KEZ45343.1 - 1.6e-42 145.5 9.7 1.9e-42 145.2 6.7 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) BBS2_C PF14782.1 KEZ45343.1 - 0.002 16.7 4.7 0.002 16.7 3.2 1.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, C-terminal CCDC144C PF14915.1 KEZ45343.1 - 0.0021 17.0 12.2 0.042 12.7 6.1 2.0 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region Myosin_tail_1 PF01576.14 KEZ45343.1 - 0.065 10.9 19.1 0.0059 14.4 10.3 1.3 2 0 0 2 2 2 0 Myosin tail DUF1664 PF07889.7 KEZ45343.1 - 0.71 9.6 6.3 0.59 9.9 3.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KEZ45343.1 - 0.94 9.5 5.7 1.5 8.9 3.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 KEZ45343.1 - 1.2 6.8 7.5 1.7 6.4 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 KEZ45343.1 - 1.3 8.0 15.7 0.22 10.5 8.0 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1068 PF06364.7 KEZ45343.1 - 1.4 8.5 7.0 2.4 7.7 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF3355 PF11835.3 KEZ45343.1 - 1.5 8.6 11.8 0.035 13.9 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3355) Vps16_N PF04841.8 KEZ45344.1 - 4.4e-89 298.8 0.0 8.2e-89 297.9 0.0 1.4 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 KEZ45344.1 - 6.1e-76 255.4 0.0 9.2e-76 254.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region FHA PF00498.21 KEZ45345.1 - 6.1e-17 61.4 0.0 1.3e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KEZ45345.1 - 3.5e-07 29.9 9.1 5.8e-07 29.2 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEZ45345.1 - 9.5e-06 25.6 3.5 1.8e-05 24.7 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEZ45345.1 - 0.0044 16.6 9.4 0.0075 15.9 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KEZ45345.1 - 0.0083 15.7 4.9 0.016 14.9 3.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 KEZ45345.1 - 0.013 15.1 7.1 0.022 14.4 4.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 KEZ45345.1 - 0.047 13.7 4.6 0.076 13.0 3.2 1.3 1 0 0 1 1 1 0 RING-like domain zf-Apc11 PF12861.2 KEZ45345.1 - 0.099 12.4 2.3 0.19 11.5 1.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 KEZ45345.1 - 0.14 12.1 10.6 0.25 11.4 7.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIIC PF12660.2 KEZ45345.1 - 0.21 11.5 2.6 0.4 10.6 1.8 1.4 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4_4 PF15227.1 KEZ45345.1 - 0.83 9.5 6.8 1.9 8.4 4.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING OrfB_Zn_ribbon PF07282.6 KEZ45345.1 - 1.1 8.9 4.2 12 5.6 1.1 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Peptidase_M16_C PF05193.16 KEZ45347.1 - 1.2e-47 161.9 0.0 3.5e-47 160.4 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KEZ45347.1 - 3.5e-41 140.4 0.0 1.5e-40 138.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) SpoIIP PF07454.6 KEZ45348.1 - 6.5 5.8 9.7 0.17 11.0 1.7 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) S1 PF00575.18 KEZ45349.1 - 3.3e-94 309.0 32.0 5.8e-18 64.7 0.1 12.6 12 0 0 12 12 12 12 S1 RNA binding domain TPR_14 PF13428.1 KEZ45349.1 - 1.2e-06 28.6 1.7 0.14 12.8 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ45349.1 - 4.9e-05 23.8 0.0 0.047 14.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ45349.1 - 9e-05 22.7 0.2 2.8 8.3 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat EF-hand_4 PF12763.2 KEZ45349.1 - 0.00025 20.7 0.0 0.00068 19.3 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand S1_2 PF13509.1 KEZ45349.1 - 0.00029 20.6 0.6 2.4 8.1 0.0 4.9 6 0 0 6 6 6 1 S1 domain PPR PF01535.15 KEZ45349.1 - 0.004 17.0 0.3 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 PPR repeat DUF3169 PF11368.3 KEZ45349.1 - 0.028 13.6 0.0 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PPR_2 PF13041.1 KEZ45349.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family MAP65_ASE1 PF03999.7 KEZ45349.1 - 2.8 6.4 15.9 13 4.2 11.0 2.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Amastin PF07344.6 KEZ45350.1 - 0.045 13.3 0.1 0.045 13.3 0.1 2.1 2 1 1 3 3 3 0 Amastin surface glycoprotein NapE PF06796.6 KEZ45350.1 - 4.1 6.8 5.8 5.5 6.3 0.2 2.8 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Methyltransf_31 PF13847.1 KEZ45351.1 - 4.9e-23 81.4 0.0 7.4e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45351.1 - 5.7e-13 49.1 0.0 1.1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ45351.1 - 3e-11 43.3 0.0 4.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45351.1 - 2.6e-10 39.8 0.0 4.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ45351.1 - 1.3e-08 35.1 0.0 3.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45351.1 - 2.6e-06 27.9 0.1 8.2e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ45351.1 - 0.00016 21.6 0.0 0.00037 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEZ45351.1 - 0.0012 18.4 0.1 0.0059 16.1 0.1 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KEZ45351.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ45351.1 - 0.0021 17.2 0.7 0.004 16.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 KEZ45351.1 - 0.0044 16.6 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 KEZ45351.1 - 0.017 14.5 0.3 0.034 13.5 0.2 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 KEZ45351.1 - 0.033 13.5 0.6 0.34 10.1 0.4 2.2 1 1 0 1 1 1 0 Histone methylation protein DOT1 CMAS PF02353.15 KEZ45351.1 - 0.055 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase bZIP_1 PF00170.16 KEZ45352.1 - 1.9e-05 24.5 3.7 3.7e-05 23.5 2.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ45352.1 - 3.5e-05 23.5 4.7 5.9e-05 22.8 3.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF3584 PF12128.3 KEZ45352.1 - 0.0012 16.3 3.5 0.0017 15.8 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DivIC PF04977.10 KEZ45352.1 - 0.01 15.2 0.6 0.022 14.2 0.4 1.5 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 KEZ45352.1 - 0.011 15.3 0.4 0.075 12.6 0.3 2.0 2 0 0 2 2 2 0 IncA protein DUF2360 PF10152.4 KEZ45352.1 - 0.023 14.9 3.1 0.056 13.7 2.1 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) TMF_DNA_bd PF12329.3 KEZ45352.1 - 0.032 14.0 0.3 0.06 13.1 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 KEZ45352.1 - 0.043 12.2 0.2 0.35 9.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF904 PF06005.7 KEZ45352.1 - 0.048 13.9 0.2 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HSBP1 PF06825.7 KEZ45352.1 - 0.089 12.3 0.2 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF812 PF05667.6 KEZ45352.1 - 0.21 10.0 2.8 0.3 9.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4094 PF13334.1 KEZ45352.1 - 0.23 11.8 1.6 0.64 10.4 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Nop25 PF09805.4 KEZ45352.1 - 0.42 10.6 4.5 0.7 9.9 3.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Herpes_UL25 PF01499.11 KEZ45352.1 - 2.2 6.5 4.3 3.1 5.9 3.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Syntaxin PF00804.20 KEZ45352.1 - 4.3 7.5 8.5 0.29 11.3 2.1 1.8 2 0 0 2 2 2 0 Syntaxin Tim17 PF02466.14 KEZ45353.1 - 0.76 9.8 8.8 0.068 13.2 1.4 2.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RRM_1 PF00076.17 KEZ45354.1 - 7.6e-16 57.5 0.0 1.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ45354.1 - 7.7e-15 54.6 0.0 1.8e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ45354.1 - 3.3e-05 23.6 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 KEZ45354.1 - 2.7 7.7 15.9 4.8 6.9 11.0 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC37_N PF03234.9 KEZ45354.1 - 7 6.9 9.4 12 6.2 6.5 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Usp PF00582.21 KEZ45355.1 - 1.3e-11 44.8 0.0 3.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Universal stress protein family Paf67 PF10255.4 KEZ45356.1 - 2e-152 507.7 1.3 2.4e-152 507.5 0.9 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KEZ45356.1 - 0.033 14.1 0.6 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ45356.1 - 1.6 8.8 4.8 12 6.0 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 KEZ45357.1 - 4.6e-55 185.9 0.0 1.1e-54 184.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KEZ45357.1 - 3e-15 55.8 0.0 9.2e-15 54.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KEZ45357.1 - 2e-11 43.7 0.0 5.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KEZ45357.1 - 1.1e-09 37.9 0.0 2.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KEZ45357.1 - 7.8e-07 28.6 0.0 7.9e-06 25.4 0.0 2.7 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KEZ45357.1 - 0.0075 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-MYND PF01753.13 KEZ45358.1 - 8.4e-05 22.3 10.7 8.4e-05 22.3 7.4 2.4 2 0 0 2 2 2 1 MYND finger JAB PF01398.16 KEZ45359.1 - 2.7e-30 104.4 0.0 3.9e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KEZ45359.1 - 2.1e-07 30.4 0.0 4.6e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NodS PF05401.6 KEZ45359.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) His_Phos_1 PF00300.17 KEZ45360.1 - 1.2e-17 64.3 0.1 2.2e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cullin PF00888.17 KEZ45361.1 - 3.5e-118 395.6 0.2 4.8e-118 395.2 0.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KEZ45361.1 - 3e-25 87.8 1.3 7.5e-25 86.5 0.9 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain PI3_PI4_kinase PF00454.22 KEZ45362.1 - 9.6e-44 149.6 0.0 2.5e-43 148.2 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KEZ45362.1 - 2.7e-31 108.3 0.0 2.8e-30 105.1 0.0 2.7 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 KEZ45362.1 - 1.1e-22 80.5 7.6 2.1e-22 79.5 5.3 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.15 KEZ45362.1 - 3.2e-12 45.6 0.0 8.9e-12 44.2 0.0 1.8 1 0 0 1 1 1 1 FATC domain DUF3414 PF11894.3 KEZ45363.1 - 0 1290.5 0.0 0 1290.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Dicty_CAD PF05720.7 KEZ45363.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Cell-cell adhesion domain DNA_pol_A PF00476.15 KEZ45364.1 - 5.6e-100 334.6 0.0 7.2e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A COesterase PF00135.23 KEZ45365.1 - 9.5e-84 282.0 0.0 1.7e-83 281.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ45365.1 - 3.3e-12 46.4 0.1 1.2e-11 44.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hce2 PF14856.1 KEZ45365.1 - 2.3e-06 27.4 0.0 5.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Peptidase_S9 PF00326.16 KEZ45365.1 - 0.011 14.9 0.3 0.019 14.1 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ45365.1 - 0.014 15.1 0.1 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PIF1 PF05970.9 KEZ45366.1 - 1.3e-58 198.6 0.3 1.6e-55 188.5 0.2 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KEZ45366.1 - 4.7e-17 62.2 0.0 9.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.1 KEZ45366.1 - 1.7e-06 27.8 0.8 4.2e-05 23.4 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 KEZ45366.1 - 4.7e-06 26.7 0.1 2.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ45366.1 - 8e-06 25.5 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KEZ45366.1 - 8.5e-05 22.6 0.0 0.00035 20.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 KEZ45366.1 - 0.00024 21.2 0.0 0.001 19.1 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 KEZ45366.1 - 0.00084 18.6 0.0 0.0026 17.0 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein Herpes_Helicase PF02689.9 KEZ45366.1 - 0.00092 17.0 0.0 0.0021 15.9 0.0 1.5 2 0 0 2 2 2 1 Helicase AAA PF00004.24 KEZ45366.1 - 0.0011 19.1 0.0 0.0034 17.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KEZ45366.1 - 0.0022 16.9 0.0 0.0047 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KEZ45366.1 - 0.011 14.7 0.1 0.21 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KEZ45366.1 - 0.012 15.8 0.0 0.052 13.8 0.0 2.1 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 KEZ45366.1 - 0.017 15.1 0.0 0.053 13.5 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KEZ45366.1 - 0.018 15.1 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KEZ45366.1 - 0.026 14.1 0.0 0.077 12.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 KEZ45366.1 - 0.028 14.0 0.6 0.088 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KEZ45366.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 KEZ45366.1 - 0.033 13.7 0.0 0.099 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KEZ45366.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KEZ45366.1 - 0.065 12.6 0.1 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 KEZ45366.1 - 0.073 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KEZ45366.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KEZ45366.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KEZ45366.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.2 KEZ45366.1 - 0.22 10.5 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 YjeF_N PF03853.10 KEZ45367.1 - 4.6e-38 130.4 0.0 6.9e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 KEZ45367.1 - 2.9e-10 40.6 0.5 8e-10 39.1 0.3 1.8 1 0 0 1 1 1 1 FDF domain Peptidase_C15 PF01470.12 KEZ45370.1 - 7.7e-13 48.7 0.0 1.8e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Pyroglutamyl peptidase PhoD PF09423.5 KEZ45371.1 - 5e-150 500.0 2.2 6.2e-150 499.7 1.6 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Aldo_ket_red PF00248.16 KEZ45373.1 - 7.4e-28 97.1 0.0 9.7e-16 57.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF1996 PF09362.5 KEZ45374.1 - 8.3e-90 300.5 0.6 1e-89 300.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FAD_binding_3 PF01494.14 KEZ45376.1 - 4.7e-13 48.9 0.1 7.8e-07 28.4 0.0 2.7 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.19 KEZ45376.1 - 1.2e-10 40.8 0.1 1.8e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ45376.1 - 6.8e-05 21.9 0.0 0.00014 20.9 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ45376.1 - 0.00036 20.4 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ45376.1 - 0.0015 18.5 0.2 0.0047 16.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KEZ45376.1 - 0.0027 16.4 0.1 1.5 7.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.19 KEZ45376.1 - 0.0032 16.3 0.0 0.01 14.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KEZ45376.1 - 0.0049 16.9 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KEZ45376.1 - 0.02 13.7 0.0 0.1 11.4 0.0 1.9 1 1 1 2 2 2 0 Squalene epoxidase GIDA PF01134.17 KEZ45376.1 - 0.074 11.9 0.0 0.15 10.9 0.0 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KEZ45376.1 - 0.078 13.3 0.0 8.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 KEZ45377.1 - 1.7e-23 82.6 0.2 2.4e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.8 KEZ45378.1 - 1.1e-10 41.1 0.0 1.9e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ45378.1 - 4.7e-06 26.7 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KEZ45378.1 - 6.4e-05 22.0 0.0 0.00011 21.3 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase p450 PF00067.17 KEZ45379.1 - 2.9e-78 263.4 0.0 1.1e-76 258.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEZ45380.1 - 1.9e-62 211.2 0.0 2.5e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 KEZ45381.1 - 6.6e-130 433.5 0.4 8.8e-130 433.1 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KEZ45381.1 - 0.00021 20.5 0.1 0.00039 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.9 KEZ45381.1 - 0.0016 17.2 0.1 0.0061 15.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DLH PF01738.13 KEZ45382.1 - 4.8e-10 39.0 0.0 5.7e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ45382.1 - 7.9e-06 25.6 0.0 3.6e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ45382.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_4 PF01565.18 KEZ45383.1 - 7.3e-27 93.5 0.0 1.4e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KEZ45383.1 - 4.5e-10 39.2 0.0 6.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain 2OG-FeII_Oxy_3 PF13640.1 KEZ45384.1 - 2e-06 28.2 0.0 5.1e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KEZ45384.1 - 0.00042 19.8 0.3 0.0014 18.1 0.2 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Beta-lactamase PF00144.19 KEZ45385.1 - 2.6e-45 154.9 0.1 1.8e-44 152.0 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase Pyr_redox_3 PF13738.1 KEZ45386.1 - 1.2e-22 80.9 0.0 4e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ45386.1 - 1.1e-16 60.1 0.4 1.7e-13 49.6 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ45386.1 - 2.4e-09 36.5 0.0 7.3e-09 34.9 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEZ45386.1 - 1.8e-08 34.5 0.0 3.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ45386.1 - 7.8e-07 29.0 0.0 7e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ45386.1 - 5e-05 22.3 0.0 0.29 9.9 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ45386.1 - 0.0066 16.2 1.8 12 5.6 0.0 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KEZ45386.1 - 0.01 14.8 0.0 0.032 13.1 0.0 1.9 3 0 0 3 3 3 1 Lycopene cyclase protein Zn_clus PF00172.13 KEZ45386.1 - 0.055 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Thi4 PF01946.12 KEZ45386.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PAN_4 PF14295.1 KEZ45387.1 - 0.096 12.4 1.1 0.69 9.6 0.7 2.2 1 1 0 1 1 1 0 PAN domain FAD_binding_3 PF01494.14 KEZ45388.1 - 3.1e-14 52.8 0.0 1.1e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ45388.1 - 4.4e-05 22.5 0.0 0.0022 16.9 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ45388.1 - 0.0018 18.6 0.4 0.01 16.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ45388.1 - 0.0022 17.9 0.1 0.007 16.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TPR_10 PF13374.1 KEZ45389.1 - 6.6e-63 207.0 11.3 2.1e-08 33.7 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ45389.1 - 7.7e-55 182.7 1.7 2.1e-13 50.0 0.3 7.5 4 2 4 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ45389.1 - 2.7e-14 52.5 0.1 0.00023 20.7 0.0 4.7 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.1 KEZ45389.1 - 1.1e-13 50.4 5.8 0.048 14.3 0.0 7.6 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ45389.1 - 1.8e-13 50.7 0.1 0.0014 19.2 0.1 4.5 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ45389.1 - 2.6e-11 42.5 2.6 0.037 13.9 0.1 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ45389.1 - 9.7e-11 40.6 3.6 0.12 12.2 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat Clr5 PF14420.1 KEZ45389.1 - 3.3e-10 39.6 0.2 9.1e-10 38.2 0.2 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_1 PF00515.23 KEZ45389.1 - 3.2e-09 36.0 1.8 0.1 12.2 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ45389.1 - 7.7e-07 28.9 10.1 0.7 10.4 0.1 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KEZ45389.1 - 3e-06 27.2 0.0 0.04 14.0 0.0 3.8 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 KEZ45389.1 - 4e-06 26.2 2.6 2 8.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ45389.1 - 4.9e-06 26.7 6.8 0.024 14.9 0.2 4.7 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_5 PF12688.2 KEZ45389.1 - 4.9e-06 26.5 7.4 0.14 12.1 0.0 4.1 4 2 0 4 4 3 2 Tetratrico peptide repeat TPR_17 PF13431.1 KEZ45389.1 - 0.00016 21.6 1.4 3.6 8.0 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat DUF4477 PF14780.1 KEZ45389.1 - 0.013 14.8 0.6 0.12 11.7 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4477) TPR_21 PF09976.4 KEZ45389.1 - 0.024 14.5 2.9 3.1 7.7 0.1 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF4404 PF14357.1 KEZ45389.1 - 0.05 14.0 4.7 0.21 12.0 0.2 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) TPR_6 PF13174.1 KEZ45389.1 - 0.11 12.9 11.1 6.7 7.4 0.1 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TBCA PF02970.11 KEZ45389.1 - 1.2 9.2 6.2 3.7 7.7 0.1 3.8 4 1 0 4 4 4 0 Tubulin binding cofactor A Patched PF02460.13 KEZ45391.1 - 0.041 11.7 0.9 0.77 7.5 0.1 2.0 2 0 0 2 2 2 0 Patched family FMN_dh PF01070.13 KEZ45392.1 - 3.1e-73 246.6 0.2 7.3e-72 242.1 0.1 2.1 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KEZ45392.1 - 1.7e-05 23.9 0.2 0.065 12.1 0.0 2.3 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.10 KEZ45392.1 - 0.027 13.6 0.1 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Glu_synthase PF01645.12 KEZ45392.1 - 0.051 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase IMPDH PF00478.20 KEZ45392.1 - 0.053 12.3 0.1 0.16 10.8 0.0 1.7 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KEZ45392.1 - 0.089 12.0 0.4 16 4.6 0.0 3.0 2 1 1 3 3 3 0 Histidine biosynthesis protein GDPD_2 PF13653.1 KEZ45392.1 - 0.12 12.6 0.4 3.2 8.0 0.3 2.8 2 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family ADH_N PF08240.7 KEZ45393.1 - 8.8e-08 31.8 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TCTP PF00838.12 KEZ45394.1 - 3.4e-64 215.7 2.1 3.8e-64 215.6 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.5 KEZ45394.1 - 0.082 11.7 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family NDUF_B4 PF07225.7 KEZ45396.1 - 0.1 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Prp18 PF02840.10 KEZ45397.1 - 1.3e-51 174.2 0.0 1.3e-51 174.2 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KEZ45397.1 - 2e-09 36.5 1.5 2e-09 36.5 1.0 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Ycf1 PF05758.7 KEZ45397.1 - 0.27 8.8 8.7 0.32 8.6 6.0 1.2 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 KEZ45397.1 - 0.56 9.6 15.3 0.98 8.8 10.6 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.9 KEZ45397.1 - 0.67 7.9 11.6 0.75 7.7 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein GST_N_3 PF13417.1 KEZ45398.1 - 3.1e-07 30.5 0.0 6.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KEZ45398.1 - 9.1e-07 28.7 0.1 2.3e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ45398.1 - 1.1e-06 28.4 0.1 2.1e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEZ45398.1 - 2.5e-05 24.3 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEZ45398.1 - 0.00016 21.5 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KEZ45398.1 - 0.00017 21.9 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WAC_Acf1_DNA_bd PF10537.4 KEZ45399.1 - 5.1e-39 132.5 0.0 1.8e-38 130.7 0.0 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KEZ45399.1 - 7.5e-17 60.8 0.9 1.2e-16 60.1 0.6 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KEZ45399.1 - 1.3e-14 53.4 0.5 2.6e-14 52.4 0.4 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KEZ45399.1 - 0.00023 20.9 0.1 0.00091 19.0 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Fijivirus_P9-2 PF06837.6 KEZ45399.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF1703 PF08011.6 KEZ45400.1 - 8.2e-05 22.2 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1703) HSDR_N_2 PF13588.1 KEZ45400.1 - 0.0036 17.0 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) CorA PF01544.13 KEZ45401.1 - 4.9e-13 48.7 1.0 1.1e-12 47.6 0.7 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EntA_Immun PF08951.5 KEZ45401.1 - 0.13 12.4 0.2 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Enterocin A Immunity Alg6_Alg8 PF03155.10 KEZ45404.1 - 8.1e-124 414.0 31.2 1.2e-122 410.0 21.6 1.9 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 KEZ45405.1 - 3.3e-23 81.9 0.0 6.2e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Legume-like lectin family Lectin_N PF03954.9 KEZ45405.1 - 0.0061 15.9 1.1 0.29 10.5 0.1 2.3 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain Translin PF01997.11 KEZ45405.1 - 0.0098 15.5 0.5 0.016 14.7 0.3 1.3 1 0 0 1 1 1 1 Translin family Baculo_PEP_C PF04513.7 KEZ45405.1 - 0.024 14.4 2.5 0.17 11.6 0.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KEZ45405.1 - 0.04 13.5 0.9 6.3 6.3 0.1 2.3 1 1 1 2 2 2 0 IncA protein Hemerythrin PF01814.18 KEZ45405.1 - 0.064 13.4 0.2 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain V_ATPase_I PF01496.14 KEZ45405.1 - 0.092 10.5 1.2 0.13 10.0 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 KEZ45405.1 - 0.21 10.0 0.6 0.29 9.4 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Striatin PF08232.7 KEZ45405.1 - 0.3 11.3 3.0 0.61 10.3 0.0 2.4 3 0 0 3 3 3 0 Striatin family DUF1664 PF07889.7 KEZ45405.1 - 0.31 10.8 2.2 1.7 8.4 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 KEZ45405.1 - 0.52 9.1 3.8 1 8.2 2.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_M24 PF00557.19 KEZ45406.1 - 1.4e-63 214.2 0.2 2.3e-63 213.5 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KEZ45406.1 - 5e-25 87.4 0.0 9.4e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.13 KEZ45406.1 - 4e-08 33.0 10.3 8.4e-08 32.0 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.18 KEZ45407.1 - 2.3e-91 306.0 37.0 2.3e-46 158.4 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KEZ45407.1 - 6.6e-68 227.2 0.0 1.3e-33 116.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ45407.1 - 1.7e-13 50.3 0.0 0.00015 21.0 0.0 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ45407.1 - 4.2e-09 36.7 0.5 0.045 13.7 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEZ45407.1 - 4.2e-09 35.7 1.3 0.00034 20.0 0.4 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ45407.1 - 9.2e-09 35.5 1.8 0.00011 22.2 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KEZ45407.1 - 7e-08 31.4 3.9 0.0049 15.5 0.1 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 KEZ45407.1 - 1.2e-06 29.2 0.0 0.071 13.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KEZ45407.1 - 2.8e-06 26.6 0.1 0.18 11.0 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KEZ45407.1 - 0.00021 21.1 1.8 0.41 10.5 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KEZ45407.1 - 0.00058 20.0 3.0 1.8 8.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEZ45407.1 - 0.0011 18.3 8.3 0.21 10.9 0.1 3.6 6 0 0 6 6 3 2 AAA domain AAA PF00004.24 KEZ45407.1 - 0.0016 18.6 2.9 11 6.2 0.0 4.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KEZ45407.1 - 0.0017 18.2 0.3 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_33 PF13671.1 KEZ45407.1 - 0.0032 17.3 0.0 3.7 7.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ45407.1 - 0.0052 16.5 0.2 3.4 7.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KEZ45407.1 - 0.0059 16.2 2.5 7.1 6.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 KEZ45407.1 - 0.0064 16.7 0.0 6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEZ45407.1 - 0.0088 16.0 1.0 0.79 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEZ45407.1 - 0.0094 15.8 0.1 3.6 7.4 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 KEZ45407.1 - 0.013 15.7 0.7 2.8 8.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 KEZ45407.1 - 0.014 14.1 0.0 2.4 6.7 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.7 KEZ45407.1 - 0.022 13.8 0.0 4.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 KEZ45407.1 - 0.03 13.2 0.0 3.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 KEZ45407.1 - 0.031 13.7 3.9 12 5.1 0.0 3.7 4 0 0 4 4 4 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KEZ45407.1 - 0.051 13.0 0.1 3.8 6.9 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KEZ45407.1 - 0.17 12.1 0.1 9 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Sporozoite_P67 PF05642.6 KEZ45408.1 - 0.0037 15.2 2.1 0.0048 14.8 1.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Fungal_trans PF04082.13 KEZ45409.1 - 9.1e-30 103.3 0.2 1.4e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPN7 PF10602.4 KEZ45410.1 - 1.6e-42 144.9 0.3 3.5e-42 143.7 0.0 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 KEZ45410.1 - 2.2e-14 53.6 0.1 3.2e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain DUF3227 PF11537.3 KEZ45410.1 - 0.042 13.9 0.1 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) DUF1299 PF06975.6 KEZ45410.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) Apc3 PF12895.2 KEZ45410.1 - 0.25 11.5 7.5 3.3 7.9 0.7 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KEZ45410.1 - 1.6 8.8 4.6 11 6.1 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BRE1 PF08647.6 KEZ45411.1 - 4.1e-24 84.3 9.2 4.1e-24 84.3 6.4 6.3 3 2 4 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KEZ45411.1 - 1.7e-09 37.5 10.9 2.8e-09 36.8 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ45411.1 - 5.2e-09 35.6 12.3 8.9e-09 34.8 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ45411.1 - 1.2e-08 34.4 9.3 1.9e-08 33.8 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ45411.1 - 6.4e-07 29.0 11.3 1e-06 28.3 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KEZ45411.1 - 7e-06 25.7 8.1 1.2e-05 25.0 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KEZ45411.1 - 0.00016 21.3 7.2 0.00041 20.0 5.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger CCDC155 PF14662.1 KEZ45411.1 - 0.00069 19.2 10.0 0.00069 19.2 7.0 4.9 2 1 3 5 5 4 1 Coiled-coil region of CCDC155 Prok-RING_4 PF14447.1 KEZ45411.1 - 0.0015 17.9 2.5 0.0032 16.9 1.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 KEZ45411.1 - 0.0025 17.5 3.1 0.0051 16.5 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF904 PF06005.7 KEZ45411.1 - 0.012 15.8 1.1 0.012 15.8 0.8 8.0 5 2 2 7 7 5 0 Protein of unknown function (DUF904) zf-C3HC4_4 PF15227.1 KEZ45411.1 - 0.015 15.1 8.3 0.029 14.2 5.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2HC_2 PF13913.1 KEZ45411.1 - 0.03 13.9 0.2 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DivIC PF04977.10 KEZ45411.1 - 0.042 13.3 55.5 0.016 14.6 3.0 8.0 5 2 4 9 9 9 0 Septum formation initiator DUF1192 PF06698.6 KEZ45411.1 - 0.11 12.3 0.2 0.11 12.3 0.1 4.2 4 0 0 4 4 3 0 Protein of unknown function (DUF1192) zf-RING_4 PF14570.1 KEZ45411.1 - 0.29 10.7 7.6 0.57 9.8 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 KEZ45411.1 - 0.35 10.7 11.9 2.4 8.1 8.0 2.3 1 1 1 2 2 2 0 FYVE zinc finger Reo_sigmaC PF04582.7 KEZ45411.1 - 0.73 8.9 27.5 0.49 9.5 3.0 3.6 2 1 1 4 4 4 0 Reovirus sigma C capsid protein APG6 PF04111.7 KEZ45411.1 - 2.5 7.0 68.3 0.45 9.5 5.3 4.3 2 1 0 4 4 4 0 Autophagy protein Apg6 bZIP_2 PF07716.10 KEZ45411.1 - 3.4 7.5 50.0 0.026 14.3 2.6 8.1 7 2 2 9 9 9 0 Basic region leucine zipper GAS PF13851.1 KEZ45411.1 - 5.1 6.2 73.1 0.03 13.4 10.8 5.7 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding zf-C2H2 PF00096.21 KEZ45411.1 - 7.8 7.0 9.3 22 5.6 0.2 3.8 4 0 0 4 4 3 0 Zinc finger, C2H2 type XPC-binding PF09280.6 KEZ45412.1 - 8.4e-25 85.9 8.6 1.4e-24 85.3 6.0 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 KEZ45412.1 - 7.6e-20 70.0 1.0 1.1e-19 69.5 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KEZ45412.1 - 6.1e-16 57.7 5.0 1.1e-07 31.5 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 KEZ45412.1 - 2.9e-10 39.6 0.8 5.1e-10 38.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEZ45412.1 - 0.00088 19.4 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KEZ45412.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 KEZ45412.1 - 0.021 15.3 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain UBA_3 PF09288.5 KEZ45412.1 - 0.1 12.1 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.1 KEZ45412.1 - 0.11 12.7 0.2 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Rap1_C PF11626.3 KEZ45412.1 - 0.16 11.8 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nol1_Nop2_Fmu PF01189.12 KEZ45413.1 - 3e-17 62.9 0.0 3.7e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Nop14 PF04147.7 KEZ45413.1 - 2 6.2 11.0 2.8 5.7 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family Hepatitis_core PF00906.15 KEZ45414.1 - 0.2 11.2 9.1 0.22 11.1 5.8 1.4 1 1 0 1 1 1 0 Hepatitis core antigen HAUS-augmin3 PF14932.1 KEZ45415.1 - 0.0015 17.7 2.0 0.0015 17.7 1.4 2.4 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 HrpB7 PF09486.5 KEZ45415.1 - 0.18 11.7 8.1 0.66 9.8 0.3 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) SlyX PF04102.7 KEZ45415.1 - 2.3 8.6 6.5 17 5.8 0.4 3.8 3 1 1 4 4 4 0 SlyX Flagellar_rod PF05149.7 KEZ45415.1 - 6.4 5.8 13.1 2 7.5 2.3 2.2 2 0 0 2 2 2 0 Paraflagellar rod protein Atg14 PF10186.4 KEZ45415.1 - 6.8 5.5 11.3 1.6 7.5 3.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PALP PF00291.20 KEZ45416.1 - 3.4e-60 203.8 0.1 4.2e-60 203.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KEZ45416.1 - 2.4e-08 33.6 0.0 2.2e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 CBS domain Ank_2 PF12796.2 KEZ45417.1 - 4.6e-58 193.5 0.0 2.3e-17 63.0 0.0 3.8 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45417.1 - 5.8e-36 120.5 0.1 5.7e-09 35.3 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KEZ45417.1 - 6.2e-27 93.0 4.6 4e-07 30.0 0.0 5.5 3 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ45417.1 - 1.7e-25 88.8 4.3 2.5e-10 40.5 0.1 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ45417.1 - 3.4e-24 82.5 0.5 1.2e-07 31.2 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat zf-DHHC PF01529.15 KEZ45417.1 - 3.6e-13 49.2 16.1 3.6e-13 49.2 11.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase TPP_enzyme_N PF02776.13 KEZ45418.1 - 1.9e-38 131.6 0.0 2.8e-37 127.8 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEZ45418.1 - 5.5e-23 81.2 0.1 9.6e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ45418.1 - 1.7e-20 73.1 0.0 1.7e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain FAD_binding_4 PF01565.18 KEZ45419.1 - 3.4e-25 88.1 4.5 5.7e-25 87.3 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ45419.1 - 7.4e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PH_10 PF15411.1 KEZ45420.1 - 4.3e-27 94.5 0.7 6.9e-27 93.9 0.5 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KEZ45420.1 - 9.3e-11 41.6 0.3 6.2e-10 38.9 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KEZ45420.1 - 6.1e-08 32.3 5.5 1.1e-07 31.5 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 KEZ45420.1 - 1.4e-07 31.4 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 KEZ45420.1 - 0.0001 21.9 5.0 0.00018 21.1 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEZ45420.1 - 0.00022 20.8 2.5 0.00038 20.0 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEZ45420.1 - 0.0011 18.9 1.8 0.0023 18.0 1.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KEZ45420.1 - 0.0032 17.4 5.0 0.0057 16.6 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ45420.1 - 0.02 14.5 5.0 0.037 13.7 3.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEZ45420.1 - 0.055 13.3 0.8 0.097 12.5 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1147 PF06615.6 KEZ45420.1 - 0.13 12.0 0.5 0.32 10.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 KEZ45420.1 - 2.4 8.2 3.9 4.6 7.3 2.7 1.5 1 0 0 1 1 1 0 RING-like domain U3_snoRNA_assoc PF08297.6 KEZ45421.1 - 2e-08 34.3 2.6 2e-08 34.3 1.8 4.0 3 2 0 3 3 3 1 U3 snoRNA associated Beta-lactamase PF00144.19 KEZ45422.1 - 3.1e-29 102.0 0.2 6e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase Dynamin_N PF00350.18 KEZ45423.1 - 3.1e-30 105.2 0.0 6.7e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KEZ45423.1 - 2.8e-17 62.4 0.0 1.2e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KEZ45423.1 - 4.5e-05 23.3 0.0 0.00017 21.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KEZ45423.1 - 9.9e-05 22.1 0.4 0.00025 20.8 0.3 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain FeoB_N PF02421.13 KEZ45423.1 - 0.022 14.0 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 KEZ45423.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KEZ45423.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KEZ45423.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KEZ45423.1 - 0.11 11.9 0.1 2.6 7.4 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KEZ45423.1 - 0.38 11.0 3.0 0.2 11.9 0.2 2.1 2 1 0 2 2 2 0 AAA domain DUF1996 PF09362.5 KEZ45424.1 - 2.9e-63 213.6 0.0 4e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) tRNA-synt_1d PF00750.14 KEZ45425.1 - 1.4e-78 264.2 6.4 7.6e-78 261.7 4.4 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KEZ45425.1 - 1.6e-28 99.0 0.0 4.2e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KEZ45425.1 - 3e-07 30.8 0.0 1.3e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Ank_2 PF12796.2 KEZ45426.1 - 3.1e-56 187.6 1.0 2.7e-22 78.8 0.0 3.7 2 1 2 4 4 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45426.1 - 1.1e-50 166.9 0.1 2.6e-09 36.4 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KEZ45426.1 - 2.7e-34 113.7 0.5 1.2e-05 25.1 0.0 8.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 KEZ45426.1 - 1.6e-33 113.9 3.1 5.7e-10 39.1 0.0 5.6 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ45426.1 - 1.3e-32 111.6 4.6 5.5e-10 39.4 0.0 7.2 1 1 6 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ45426.1 - 1.9e-07 30.9 0.0 5.8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ45426.1 - 1.3e-05 25.3 0.0 5.3e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ45426.1 - 0.00016 21.6 0.0 0.00045 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain EPSP_synthase PF00275.15 KEZ45426.1 - 0.0083 14.5 0.1 3 6.1 0.0 3.5 1 1 3 4 4 4 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) AAA_17 PF13207.1 KEZ45426.1 - 0.076 13.8 0.0 0.69 10.7 0.0 2.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KEZ45426.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain HTH_11 PF08279.7 KEZ45426.1 - 1.7 8.3 6.0 2e+02 1.7 0.0 5.5 7 0 0 7 7 7 0 HTH domain Ferric_reduct PF01794.14 KEZ45427.1 - 1.1e-16 60.9 12.1 1.1e-16 60.9 8.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KEZ45427.1 - 3.6e-13 49.2 0.0 7.7e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KEZ45427.1 - 1.1e-10 41.6 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KEZ45427.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF3746 PF12562.3 KEZ45427.1 - 0.079 12.8 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) Zona_pellucida PF00100.18 KEZ45427.1 - 0.095 12.1 0.4 0.89 8.9 0.0 2.0 1 1 1 2 2 2 0 Zona pellucida-like domain Secretin_N_2 PF07655.8 KEZ45428.1 - 3.9 7.9 10.9 7.2 7.0 7.6 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain RINGv PF12906.2 KEZ45429.1 - 1.2e-16 60.4 9.5 2.1e-16 59.7 6.6 1.4 1 0 0 1 1 1 1 RING-variant domain CBP4 PF07960.6 KEZ45429.1 - 0.08 12.5 1.1 0.21 11.2 0.8 1.6 1 0 0 1 1 1 0 CBP4 zf-RING_2 PF13639.1 KEZ45429.1 - 0.13 12.0 8.8 0.24 11.2 6.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 KEZ45429.1 - 0.4 10.5 2.5 0.92 9.3 1.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger YL1 PF05764.8 KEZ45431.1 - 0.0014 18.2 10.2 0.0014 18.2 7.0 2.7 3 0 0 3 3 3 1 YL1 nuclear protein HeLo PF14479.1 KEZ45431.1 - 0.0018 18.0 6.8 0.0084 15.8 0.1 3.2 2 1 0 2 2 2 1 Prion-inhibition and propagation Nop14 PF04147.7 KEZ45431.1 - 9.1 4.0 25.1 0.4 8.5 4.4 2.3 2 0 0 2 2 2 0 Nop14-like family DUF814 PF05670.8 KEZ45432.1 - 2.9e-23 81.5 0.1 6e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) BSMAP PF12280.3 KEZ45432.1 - 0.3 10.9 3.8 0.42 10.4 2.7 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein BTB PF00651.26 KEZ45433.1 - 1.6e-06 28.0 0.0 9.2e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain DUF948 PF06103.6 KEZ45434.1 - 0.00083 19.1 0.9 1.4 8.7 0.1 4.0 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF948) MbeD_MobD PF04899.7 KEZ45434.1 - 0.083 12.8 2.9 25 4.8 0.5 4.2 4 0 0 4 4 4 0 MbeD/MobD like DUF2365 PF10157.4 KEZ45434.1 - 1.2 9.0 9.1 0.78 9.6 0.7 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2365) V_ATPase_I PF01496.14 KEZ45434.1 - 1.3 6.7 6.6 2.5 5.8 4.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.1 KEZ45434.1 - 1.3 8.9 13.0 13 5.7 1.3 4.4 4 0 0 4 4 4 0 FlxA-like protein DUF148 PF02520.12 KEZ45434.1 - 2.6 7.8 9.5 1.6 8.5 1.5 3.2 2 1 1 3 3 3 0 Domain of unknown function DUF148 ALMT PF11744.3 KEZ45434.1 - 3.9 6.0 6.3 7.7 5.0 4.4 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter TT_ORF1 PF02956.9 KEZ45434.1 - 4.4 5.6 6.2 6.8 5.0 4.3 1.2 1 0 0 1 1 1 0 TT viral orf 1 LrgB PF04172.11 KEZ45435.1 - 7.2e-15 54.7 3.6 1.9e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 LrgB-like family Rotamase PF00639.16 KEZ45436.1 - 7.2e-23 81.1 0.0 9.6e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KEZ45436.1 - 9.8e-18 64.5 0.0 1.3e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KEZ45436.1 - 4.5e-07 30.5 0.0 1e-06 29.3 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KEZ45436.1 - 6.7e-06 25.8 1.5 6.7e-06 25.8 1.0 2.0 3 0 0 3 3 3 1 WW domain Terminase_6 PF03237.10 KEZ45436.1 - 0.08 11.6 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family SUN PF03856.8 KEZ45436.1 - 0.13 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) Ribosomal_L14 PF00238.14 KEZ45437.1 - 5.1e-44 148.9 2.9 5.6e-44 148.8 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 KEZ45438.1 - 4.8e-09 36.7 0.0 2.1e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 SET domain Peptidase_M24 PF00557.19 KEZ45439.1 - 2.2e-54 184.1 0.0 3.2e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KEZ45439.1 - 2.4e-24 85.2 0.0 7.2e-24 83.6 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain p450 PF00067.17 KEZ45440.1 - 2.7e-49 167.9 0.0 3.6e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 KEZ45441.1 - 2.3e-49 167.5 4.2 5.3e-49 166.3 2.9 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ45441.1 - 1.3e-17 64.9 3.1 1.8e-15 57.9 2.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ45441.1 - 3.7e-08 33.7 0.0 1.1e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KEZ45441.1 - 9.4e-08 32.0 0.0 3.6e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2929 PF11151.3 KEZ45441.1 - 1.1 9.3 10.7 0.38 10.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) SAD_SRA PF02182.12 KEZ45442.1 - 4e-25 87.9 0.3 5.7e-25 87.4 0.2 1.2 1 0 0 1 1 1 1 SAD/SRA domain Amidohydro_1 PF01979.15 KEZ45443.1 - 2.3e-06 27.5 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KEZ45443.1 - 1e-05 25.2 0.1 2.7e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KEZ45443.1 - 4.5e-05 22.8 0.4 0.00066 19.0 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase family DUF2288 PF10052.4 KEZ45444.1 - 0.031 14.0 0.1 0.087 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) Auxin_canalis PF05703.6 KEZ45444.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Auxin canalisation Fe-S_biosyn PF01521.15 KEZ45445.1 - 5.8e-16 58.4 0.0 7.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF605 PF04652.11 KEZ45445.1 - 3.6 6.8 12.2 4.6 6.5 8.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF1741 PF08427.5 KEZ45446.1 - 1.7e-86 289.5 0.0 3e-86 288.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) tRNA-synt_1c PF00749.16 KEZ45447.1 - 3.1e-98 328.3 0.0 4.3e-98 327.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEZ45447.1 - 5e-28 97.9 0.0 1.4e-27 96.4 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Bromodomain PF00439.20 KEZ45448.1 - 8.4e-31 105.7 0.0 6.7e-20 70.8 0.0 2.8 2 0 0 2 2 2 2 Bromodomain Methyltransf_23 PF13489.1 KEZ45449.1 - 5.1e-17 62.0 0.0 8.2e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45449.1 - 3.4e-09 37.2 0.0 6.3e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45449.1 - 5.1e-09 36.5 0.0 1.8e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45449.1 - 4.6e-08 32.7 0.0 2.2e-06 27.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45449.1 - 5.7e-07 29.9 0.0 7.1e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ45449.1 - 0.00093 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KEZ45449.1 - 0.0013 18.7 0.0 0.052 13.5 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ45449.1 - 0.005 16.3 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KEZ45449.1 - 0.0095 15.3 0.0 0.046 13.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KEZ45449.1 - 0.011 16.0 0.0 0.048 14.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45449.1 - 0.014 14.5 0.0 0.25 10.4 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEZ45449.1 - 0.04 12.9 0.0 0.092 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KEZ45449.1 - 0.048 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase U1snRNP70_N PF12220.3 KEZ45450.1 - 0.063 13.6 0.4 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Peptidase_M3 PF01432.15 KEZ45451.1 - 5.1e-120 401.5 0.0 6.3e-120 401.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Phage_DsbA PF11126.3 KEZ45451.1 - 0.19 11.8 0.2 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator DsbA Peptidase_M50B PF13398.1 KEZ45451.1 - 0.32 10.3 0.7 1 8.6 0.2 1.8 2 0 0 2 2 2 0 Peptidase M50B-like CFEM PF05730.6 KEZ45452.1 - 3.4e-09 36.3 6.3 4.5e-09 35.9 4.4 1.2 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 KEZ45452.1 - 0.37 10.8 4.0 0.86 9.6 2.8 1.5 1 0 0 1 1 1 0 Gamma-thionin family RR_TM4-6 PF06459.7 KEZ45452.1 - 2.7 7.8 16.5 3.2 7.5 11.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 KEZ45452.1 - 9.8 5.6 7.6 13 5.2 5.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Glyco_hydro_67N PF03648.9 KEZ45453.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus CLN3 PF02487.12 KEZ45454.1 - 3.6e-103 345.4 19.0 3.3e-95 319.2 7.1 2.4 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 KEZ45454.1 - 0.0015 17.3 10.6 0.0015 17.3 7.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4536 PF15055.1 KEZ45454.1 - 0.89 9.6 6.5 2.8 8.0 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) DUF2183 PF09949.4 KEZ45455.1 - 3.5e-30 103.8 0.0 7e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2434 PF10361.4 KEZ45456.1 - 2.4e-112 374.8 13.5 3e-112 374.5 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.4 KEZ45457.1 - 6e-32 110.3 0.9 6e-32 110.3 0.6 2.7 2 1 1 3 3 3 1 Golgi transport complex subunit 5 SPX PF03105.14 KEZ45457.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 SPX domain IncA PF04156.9 KEZ45457.1 - 0.32 10.5 2.8 0.25 10.9 0.7 1.7 2 0 0 2 2 2 0 IncA protein Polysacc_deac_1 PF01522.16 KEZ45458.1 - 2.4e-27 95.0 0.0 3.4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KEZ45458.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Glyco_hydro_18 PF00704.23 KEZ45460.1 - 3.1e-44 151.8 0.1 4.9e-44 151.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KEZ45460.1 - 5.5e-05 22.9 0.1 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 LysM domain Chitin_bind_1 PF00187.14 KEZ45460.1 - 0.0017 18.3 2.2 0.0017 18.3 1.5 3.5 3 0 0 3 3 3 1 Chitin recognition protein ETRAMP PF09716.5 KEZ45460.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-BED PF02892.10 KEZ45460.1 - 0.15 11.8 4.8 0.46 10.2 3.3 1.9 1 0 0 1 1 1 0 BED zinc finger Fungal_trans PF04082.13 KEZ45461.1 - 2.1e-18 66.1 0.0 3.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ45463.1 - 5.7e-24 84.4 64.8 3.1e-23 82.0 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3638 PF12340.3 KEZ45464.1 - 1.9e-95 318.1 0.3 2.4e-73 245.9 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 KEZ45464.1 - 2.6e-15 55.2 1.4 4.4e-15 54.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) Mito_carr PF00153.22 KEZ45465.1 - 3.5e-34 116.3 5.2 7.6e-16 57.6 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_23 PF13489.1 KEZ45465.1 - 1.2e-12 47.8 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45465.1 - 1.3e-11 44.3 0.0 2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45465.1 - 3.9e-11 43.2 0.0 1e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45465.1 - 2.3e-10 40.8 0.0 5.9e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45465.1 - 3.2e-08 34.1 0.0 5.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ45465.1 - 4.3e-05 23.5 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45465.1 - 8.5e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Zip PF02535.17 KEZ45465.1 - 0.00057 19.0 0.5 0.00075 18.5 0.3 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Coatomer_WDAD PF04053.9 KEZ45466.1 - 8.5e-148 492.8 0.0 1.4e-147 492.0 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KEZ45466.1 - 1.8e-86 290.3 0.0 2.9e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus SNF2_N PF00176.18 KEZ45466.1 - 8.9e-69 231.5 0.0 1.4e-68 230.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain WD40 PF00400.27 KEZ45466.1 - 9.8e-51 167.9 12.4 4.5e-09 35.8 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Rad54_N PF08658.5 KEZ45466.1 - 1.7e-46 158.5 0.7 1.1e-45 155.7 0.5 2.3 2 0 0 2 2 2 1 Rad54 N terminal Pkinase PF00069.20 KEZ45466.1 - 8.8e-22 77.4 0.0 2.2e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Helicase_C PF00271.26 KEZ45466.1 - 1.4e-12 47.2 0.0 4.3e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KEZ45466.1 - 3.5e-05 22.7 0.0 9.8e-05 21.3 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KEZ45466.1 - 9.1e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase_Tyr PF07714.12 KEZ45466.1 - 0.0019 17.3 0.3 0.043 12.8 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Nup160 PF11715.3 KEZ45466.1 - 0.025 12.7 6.3 0.54 8.3 0.0 3.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.15 KEZ45466.1 - 0.071 12.7 0.3 0.76 9.3 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS SAC3_GANP PF03399.11 KEZ45467.1 - 1e-24 87.2 0.0 1.6e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEZ45467.1 - 3.5e-20 72.2 0.0 5.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Sel1 PF08238.7 KEZ45468.1 - 2.5e-13 50.1 28.7 4.4e-06 27.1 0.3 7.5 6 1 1 7 7 7 4 Sel1 repeat TPR_1 PF00515.23 KEZ45468.1 - 0.0027 17.2 0.4 0.01 15.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ45468.1 - 0.0042 16.6 1.9 0.031 13.9 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 KEZ45468.1 - 0.071 12.9 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ45468.1 - 0.1 12.5 0.8 3.2 7.8 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ45468.1 - 2.2 9.1 4.9 3.5 8.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat UDP-g_GGTase PF06427.6 KEZ45469.1 - 5.2e-62 208.8 0.0 2.8e-61 206.5 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KEZ45469.1 - 7.8e-06 25.3 0.4 1.9e-05 24.1 0.3 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 PAS_9 PF13426.1 KEZ45470.1 - 4e-32 110.6 0.0 4.8e-19 68.6 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 KEZ45470.1 - 3.5e-18 65.4 0.0 5.4e-10 39.2 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 KEZ45470.1 - 2.3e-16 59.5 0.0 2.8e-05 23.8 0.0 3.8 3 1 0 3 3 3 3 PAS fold GATA PF00320.22 KEZ45470.1 - 2.4e-15 55.5 8.1 5.6e-15 54.4 5.6 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 KEZ45470.1 - 6.4e-12 45.4 0.0 0.00014 21.8 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 KEZ45470.1 - 1.3e-06 28.3 0.0 0.08 12.8 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.1 KEZ45470.1 - 0.014 15.2 0.0 0.94 9.4 0.0 2.6 2 0 0 2 2 2 0 PAS domain HEAT_2 PF13646.1 KEZ45471.1 - 5.5e-23 81.0 8.4 3.3e-10 40.1 0.0 8.9 5 3 5 10 10 9 7 HEAT repeats HEAT PF02985.17 KEZ45471.1 - 1.6e-21 74.3 8.3 0.0012 18.7 0.0 9.8 9 0 0 9 9 8 5 HEAT repeat HEAT_EZ PF13513.1 KEZ45471.1 - 1.2e-20 73.3 16.0 1.1e-08 35.2 0.1 9.8 9 2 4 13 13 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KEZ45471.1 - 1.4e-11 44.6 0.0 0.01 16.1 0.0 7.0 5 2 3 8 8 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KEZ45471.1 - 9.4e-09 34.9 0.0 0.0025 17.1 0.2 5.1 4 1 0 5 5 5 1 CLASP N terminal RIX1 PF08167.7 KEZ45471.1 - 1.8e-06 27.7 0.0 0.019 14.6 0.0 4.4 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 KEZ45471.1 - 5.1e-06 25.4 0.1 5.1e-06 25.4 0.1 3.4 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 KEZ45471.1 - 1.1e-05 24.0 1.5 0.0027 16.1 0.1 3.8 3 1 2 5 5 5 1 Adaptin N terminal region TAN PF11640.3 KEZ45471.1 - 0.00075 19.2 1.3 0.25 11.0 0.1 3.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair Proteasom_PSMB PF10508.4 KEZ45471.1 - 0.0013 17.1 0.7 0.0065 14.7 0.0 2.6 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KEZ45471.1 - 0.0016 18.2 0.5 0.46 10.3 0.0 4.2 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KEZ45471.1 - 0.0046 16.8 2.1 0.017 14.9 0.2 3.0 3 0 0 3 3 2 1 Importin-beta N-terminal domain Arm PF00514.18 KEZ45471.1 - 0.005 16.6 9.4 1.4 8.8 0.0 5.4 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 KEZ45471.1 - 0.0059 16.5 1.3 5.9 6.7 0.0 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) V-ATPase_H_N PF03224.9 KEZ45471.1 - 0.007 15.5 2.5 0.33 10.0 0.0 3.2 3 0 0 3 3 3 1 V-ATPase subunit H CAS_CSE1 PF03378.10 KEZ45471.1 - 0.0095 14.2 0.7 1.4 7.0 0.0 3.3 4 0 0 4 4 4 1 CAS/CSE protein, C-terminus SEN1_N PF12726.2 KEZ45471.1 - 0.01 13.9 0.2 0.87 7.5 0.0 2.4 2 0 0 2 2 2 0 SEN1 N terminal DRIM PF07539.7 KEZ45471.1 - 0.032 13.6 0.5 0.14 11.6 0.3 2.1 1 0 0 1 1 1 0 Down-regulated in metastasis Cohesin_HEAT PF12765.2 KEZ45471.1 - 0.033 14.1 0.0 15 5.6 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.1 KEZ45471.1 - 0.076 12.4 0.2 8.6 5.7 0.0 4.1 5 1 0 5 5 5 0 Domain of unknown function (DUF4042) CBS PF00571.23 KEZ45472.1 - 3.4e-19 68.3 2.5 0.00044 19.9 0.1 5.3 5 0 0 5 5 5 5 CBS domain Ytp1 PF10355.4 KEZ45473.1 - 8.7e-92 307.1 3.0 1.4e-91 306.4 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KEZ45473.1 - 6e-31 106.1 6.5 6e-31 106.1 4.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Rsa3 PF14615.1 KEZ45473.1 - 1.4e-13 49.9 0.0 2.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF3481 PF11980.3 KEZ45473.1 - 0.15 11.8 0.0 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) UCH PF00443.24 KEZ45474.1 - 8.7e-39 133.2 1.0 1.3e-38 132.6 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ45474.1 - 1.9e-24 86.6 0.5 2.6e-24 86.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KEZ45474.1 - 0.00028 20.9 0.4 0.00028 20.9 0.3 2.8 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein NAD_binding_10 PF13460.1 KEZ45475.1 - 6.3e-11 42.6 0.0 8.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEZ45475.1 - 5.9e-07 29.1 0.1 2e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEZ45475.1 - 1.2e-05 24.7 0.0 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KEZ45475.1 - 1.3e-05 24.1 0.0 3e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KEZ45475.1 - 0.0059 15.5 0.0 0.016 14.1 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain PCI PF01399.22 KEZ45476.1 - 1e-12 48.2 0.0 2.5e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain Spo0A_C PF08769.6 KEZ45476.1 - 0.007 16.2 0.0 0.063 13.1 0.0 2.2 1 1 1 2 2 2 1 Sporulation initiation factor Spo0A C terminal Aconitase PF00330.15 KEZ45477.1 - 3.9e-174 579.4 0.0 1.2e-173 577.8 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEZ45477.1 - 9.8e-46 155.1 0.0 1.7e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 KEZ45478.1 - 4.6e-09 36.1 0.8 1e-08 35.0 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ45478.1 - 0.00089 19.3 0.7 0.0019 18.3 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEZ45478.1 - 0.046 14.0 1.0 0.046 14.0 0.7 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEZ45478.1 - 0.079 13.0 0.4 0.12 12.5 0.3 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Prim_Zn_Ribbon PF08273.7 KEZ45478.1 - 0.11 12.5 0.2 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DUF3279 PF11682.3 KEZ45478.1 - 0.16 11.5 1.0 0.37 10.3 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) CRAL_TRIO PF00650.15 KEZ45479.1 - 2.5e-43 147.2 0.0 5.8e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KEZ45479.1 - 2.5e-15 56.3 0.0 7.4e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KEZ45479.1 - 1.9e-10 40.7 0.0 4.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 KEZ45480.1 - 8.2e-22 77.5 0.2 1.1e-21 77.1 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KEZ45480.1 - 2.5e-15 56.6 0.1 3.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KEZ45480.1 - 8.9e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mog1 PF04603.7 KEZ45481.1 - 3.9e-19 68.9 0.0 5.1e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Glucan_synthase PF02364.10 KEZ45482.1 - 0 1446.0 0.0 0 1445.2 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KEZ45482.1 - 1.5e-39 134.5 0.5 3.9e-39 133.1 0.3 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 KEZ45483.1 - 5.1e-30 104.6 0.0 7e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KEZ45483.1 - 0.0082 14.4 0.0 0.013 13.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme APH PF01636.18 KEZ45484.1 - 0.012 15.3 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ45484.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HET PF06985.6 KEZ45486.1 - 1.6e-29 102.8 0.0 2.8e-29 102.0 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEZ45488.1 - 8.4e-34 116.8 31.5 1.3e-33 116.1 21.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1180 PF06679.7 KEZ45488.1 - 0.11 12.3 0.1 0.28 11.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Peptidase_M20 PF01546.23 KEZ45489.1 - 1.3e-08 34.5 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEZ45489.1 - 9.5e-07 28.5 0.1 7.4e-06 25.6 0.0 2.4 2 1 0 2 2 2 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 KEZ45490.1 - 8.1e-10 37.8 0.1 1e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NACHT PF05729.7 KEZ45491.1 - 5.9e-12 45.5 0.1 2.9e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ45491.1 - 0.0002 21.5 0.0 0.0065 16.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KEZ45491.1 - 0.0097 16.2 0.5 0.51 10.6 0.0 3.1 3 1 0 3 3 3 1 ABC transporter NB-ARC PF00931.17 KEZ45491.1 - 0.019 13.8 0.1 0.51 9.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Phasin PF05597.6 KEZ45491.1 - 0.019 14.7 2.6 0.1 12.3 1.8 2.2 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AAA_18 PF13238.1 KEZ45491.1 - 0.035 14.4 0.0 0.22 11.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ45491.1 - 0.038 12.9 0.0 5.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RPN7 PF10602.4 KEZ45491.1 - 0.039 13.3 0.1 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Ank PF00023.25 KEZ45491.1 - 0.041 13.6 0.1 1.9 8.4 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat PRK PF00485.13 KEZ45491.1 - 0.049 13.1 0.2 0.68 9.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family HsbA PF12296.3 KEZ45491.1 - 0.062 13.1 0.8 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF4239 PF14023.1 KEZ45491.1 - 0.091 12.1 1.8 0.37 10.1 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4239) AAA_17 PF13207.1 KEZ45491.1 - 0.1 13.4 1.3 0.41 11.4 0.1 2.7 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KEZ45491.1 - 0.14 11.6 0.5 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KEZ45491.1 - 0.16 11.3 0.7 1.1 8.6 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 KEZ45491.1 - 0.18 11.9 0.4 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 KEZ45491.1 - 0.22 11.0 1.0 0.42 10.1 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 KEZ45491.1 - 0.66 10.2 2.9 8.7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain MCPsignal PF00015.16 KEZ45491.1 - 1.3 8.5 6.4 4.7 6.6 2.9 2.5 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Phage_GP20 PF06810.6 KEZ45491.1 - 1.8 7.9 4.8 0.94 8.9 0.8 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 HET PF06985.6 KEZ45493.1 - 5.2e-19 68.7 0.0 1.1e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTG PF07742.7 KEZ45493.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 BTG family AAA PF00004.24 KEZ45494.1 - 1.3e-17 64.2 0.0 2.3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ45494.1 - 2e-05 24.7 0.2 0.00069 19.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ45494.1 - 0.00021 22.0 2.5 0.00029 21.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEZ45494.1 - 0.00041 20.6 0.0 0.00094 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ45494.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KEZ45494.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 KEZ45494.1 - 0.004 16.2 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KEZ45494.1 - 0.018 14.8 0.1 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KEZ45494.1 - 0.019 14.9 0.4 0.075 13.0 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_2 PF07724.9 KEZ45494.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 KEZ45494.1 - 0.072 12.2 0.2 0.22 10.6 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEZ45494.1 - 0.077 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KEZ45494.1 - 0.09 12.7 0.3 0.2 11.6 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 KEZ45494.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KEZ45494.1 - 0.18 10.9 0.0 0.42 9.7 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Glyco_hydro_61 PF03443.9 KEZ45495.1 - 3.4e-44 151.2 0.2 2.8e-43 148.2 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 KEZ45495.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.5 1 1 0 1 1 1 0 Wzt C-terminal domain Copper-bind PF00127.15 KEZ45496.1 - 0.025 14.8 0.4 0.043 14.0 0.3 1.4 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 KEZ45496.1 - 0.048 13.4 0.6 0.15 11.9 0.4 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain DUF1116 PF06545.6 KEZ45497.1 - 0.0029 16.7 0.3 0.0047 16.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1116) ketoacyl-synt PF00109.21 KEZ45498.1 - 2.5e-68 230.3 0.1 2.5e-68 230.3 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEZ45498.1 - 1.3e-55 187.8 0.9 6.3e-55 185.6 0.0 2.6 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 KEZ45498.1 - 5.2e-55 186.6 0.0 8.9e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KEZ45498.1 - 9.1e-46 155.8 0.1 2.7e-45 154.2 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEZ45498.1 - 8.9e-41 138.4 0.1 1.9e-40 137.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KEZ45498.1 - 2.6e-35 122.3 0.1 5.8e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.7 KEZ45498.1 - 3.4e-18 65.9 0.0 4.2e-17 62.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KEZ45498.1 - 1.5e-11 45.2 0.0 2.3e-10 41.4 0.0 3.1 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KEZ45498.1 - 4.8e-11 42.3 0.0 6.7e-10 38.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEZ45498.1 - 1e-09 38.2 0.0 2.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KEZ45498.1 - 2.7e-08 33.9 0.2 6.8e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 KEZ45498.1 - 7.8e-08 32.0 0.0 2.4e-07 30.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45498.1 - 1.1e-07 32.1 0.0 8e-07 29.4 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45498.1 - 1.6e-07 31.9 0.1 2.3e-06 28.1 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45498.1 - 2.2e-06 26.9 0.0 4.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ45498.1 - 0.0036 17.6 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KEZ45498.1 - 0.0082 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KEZ45498.1 - 0.0083 14.8 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 KEZ45498.1 - 0.0083 15.1 2.0 0.12 11.3 0.0 2.9 4 0 0 4 4 4 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 KEZ45498.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 KEZ45498.1 - 0.033 14.1 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain MBOAT_2 PF13813.1 KEZ45499.1 - 1.4e-16 60.3 0.8 3.6e-16 59.0 0.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 KEZ45500.1 - 5.3e-47 160.3 0.0 9.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KEZ45501.1 - 2.9e-11 43.3 0.0 8.8e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45501.1 - 5.4e-07 29.3 0.0 0.00043 19.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45501.1 - 7.8e-07 29.6 0.0 2.8e-05 24.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45501.1 - 1.2e-05 25.6 0.0 0.00018 21.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45501.1 - 0.00013 22.3 0.0 0.00099 19.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45501.1 - 0.00065 18.8 0.0 0.0083 15.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.6 KEZ45501.1 - 0.0042 15.8 0.0 0.0069 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Antibiotic_NAT PF02522.9 KEZ45501.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Zn_clus PF00172.13 KEZ45502.1 - 0.12 12.2 2.9 0.23 11.3 2.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KEZ45503.1 - 1.6e-33 115.9 0.0 2.3e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AIG2_2 PF13772.1 KEZ45504.1 - 5.1e-05 23.3 0.0 0.0061 16.6 0.0 2.3 2 0 0 2 2 2 2 AIG2-like family AIG2 PF06094.7 KEZ45504.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family AMP-binding PF00501.23 KEZ45505.1 - 3.8e-73 246.2 0.0 5.8e-73 245.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KEZ45505.1 - 4.4e-47 160.3 0.0 1.7e-22 79.6 0.0 3.1 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 KEZ45505.1 - 3.8e-13 49.4 0.1 2.2e-07 31.0 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KEZ45505.1 - 0.00021 21.5 0.0 0.00053 20.2 0.0 1.7 1 0 0 1 1 1 1 HxxPF-repeated domain AMP-binding_C PF13193.1 KEZ45505.1 - 0.0005 20.9 0.1 0.0015 19.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 KEZ45506.1 - 1.8e-28 99.5 0.0 1.8e-21 76.5 0.0 3.0 2 1 1 3 3 3 3 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ45506.1 - 0.00092 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Scm3 PF10384.4 KEZ45506.1 - 0.13 11.7 0.1 6.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Centromere protein Scm3 Pyr_redox_2 PF07992.9 KEZ45507.1 - 6.6e-20 71.8 0.0 8.6e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ45507.1 - 1e-06 28.6 0.6 0.038 13.7 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KEZ45507.1 - 6e-06 25.3 0.0 1.4e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KEZ45507.1 - 1.5e-05 23.6 0.0 0.013 13.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 KEZ45507.1 - 0.00014 22.0 1.8 0.05 13.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ45507.1 - 0.00043 19.2 2.2 0.00074 18.5 1.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ45507.1 - 0.0019 18.1 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KEZ45507.1 - 0.0032 16.5 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KEZ45507.1 - 0.0045 15.9 0.5 0.012 14.4 0.4 1.7 1 1 1 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KEZ45507.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KEZ45507.1 - 0.014 14.3 0.4 0.044 12.6 0.1 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.1 KEZ45507.1 - 0.062 12.2 0.1 0.98 8.2 0.0 2.3 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KEZ45507.1 - 0.077 11.6 0.6 0.14 10.7 0.4 1.4 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 KEZ45507.1 - 3.9 6.4 6.3 1.9 7.4 2.5 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.13 KEZ45508.1 - 1.2e-38 132.7 0.0 1.7e-38 132.1 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KEZ45508.1 - 0.023 14.4 0.0 0.072 12.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45508.1 - 0.04 14.5 0.1 0.29 11.7 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain GST_N_2 PF13409.1 KEZ45509.1 - 1.2e-06 28.3 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KEZ45509.1 - 2.1e-06 27.8 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KEZ45509.1 - 2.5e-06 27.3 0.0 4.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KEZ45509.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ45509.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Prenyltrans_1 PF13243.1 KEZ45509.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Prenyltransferase-like adh_short PF00106.20 KEZ45510.1 - 1.1e-16 61.2 0.2 2.1e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ45510.1 - 1.9e-08 34.1 0.1 3.9e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ45510.1 - 8.3e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KEZ45510.1 - 0.019 14.3 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEZ45510.1 - 0.029 14.3 0.2 0.072 13.0 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding DUF1857 PF08982.6 KEZ45511.1 - 2.1e-23 82.5 0.1 7.8e-23 80.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1857) CorA PF01544.13 KEZ45511.1 - 1.2e-09 37.6 1.6 6.3e-08 32.0 0.1 2.6 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein FlaC_arch PF05377.6 KEZ45511.1 - 0.0053 16.6 3.7 0.0077 16.1 0.2 2.9 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) IncA PF04156.9 KEZ45511.1 - 8.9 5.8 7.8 58 3.1 5.0 2.3 1 1 1 2 2 2 0 IncA protein TPR_12 PF13424.1 KEZ45512.1 - 1.7e-13 50.3 3.9 4.9e-05 23.1 0.4 4.9 3 1 2 5 5 5 4 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ45512.1 - 3.6e-11 42.4 0.0 7.3e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KEZ45512.1 - 6e-06 26.3 0.1 5.2e-05 23.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain TPR_11 PF13414.1 KEZ45512.1 - 2e-05 24.1 3.2 0.019 14.5 0.0 3.9 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 KEZ45512.1 - 2.6e-05 23.6 1.0 0.45 10.2 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 KEZ45512.1 - 0.0001 22.4 0.0 0.00047 20.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain Apc3 PF12895.2 KEZ45512.1 - 0.0019 18.2 0.3 1.6 8.9 0.0 3.1 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 Arch_ATPase PF01637.13 KEZ45512.1 - 0.017 14.7 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF87 PF01935.12 KEZ45512.1 - 0.034 13.9 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 TPR_10 PF13374.1 KEZ45512.1 - 0.047 13.6 0.2 39 4.3 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ45512.1 - 0.063 13.2 7.4 1.7 8.7 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_30 PF13604.1 KEZ45512.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M49 PF03571.10 KEZ45515.1 - 2e-178 593.9 0.0 2.3e-178 593.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Aa_trans PF01490.13 KEZ45517.1 - 1.3e-25 89.7 37.8 1.6e-25 89.4 26.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3671 PF12420.3 KEZ45517.1 - 0.024 14.5 0.9 0.024 14.5 0.6 3.2 4 0 0 4 4 4 0 Protein of unknown function Glyco_hydro_31 PF01055.21 KEZ45518.1 - 3.9e-166 553.2 1.5 4.8e-166 552.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KEZ45518.1 - 1.3e-10 41.0 1.8 4.7e-10 39.1 1.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Epimerase PF01370.16 KEZ45519.1 - 3.4e-19 69.2 0.0 4.4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEZ45519.1 - 4e-10 38.8 0.0 6.8e-10 38.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEZ45519.1 - 3.1e-09 37.0 0.5 5.4e-09 36.3 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEZ45519.1 - 1.3e-06 27.5 0.1 2.4e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KEZ45519.1 - 2e-05 24.5 3.6 4.3e-05 23.4 1.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ45519.1 - 0.0018 17.9 2.5 0.013 15.2 1.7 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 KEZ45519.1 - 0.0047 16.2 0.1 0.0077 15.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Ada_Zn_binding PF02805.11 KEZ45520.1 - 1.2e-28 98.5 2.7 2e-28 97.7 1.9 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KEZ45520.1 - 9.6e-09 34.8 0.0 3.3e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KEZ45520.1 - 2.3e-06 27.6 0.0 2.9e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HNH_2 PF13391.1 KEZ45521.1 - 3.8e-05 23.3 0.1 7.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease Tyrosinase PF00264.15 KEZ45522.1 - 1.3e-21 77.7 2.4 1.4e-21 77.7 0.1 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase CsbD PF05532.7 KEZ45523.1 - 9.6e-07 28.3 0.2 9.6e-07 28.3 0.1 3.2 2 1 1 3 3 3 1 CsbD-like CBM_4_9 PF02018.12 KEZ45524.1 - 4.5e-09 36.4 0.2 2.4e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate binding domain ADH_N PF08240.7 KEZ45525.1 - 3.5e-24 84.6 1.6 3.5e-24 84.6 1.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ45525.1 - 4.5e-14 52.1 2.5 2.7e-13 49.5 0.8 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase tRNA-synt_1e PF01406.14 KEZ45526.1 - 2.1e-108 361.9 0.0 3.4e-108 361.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KEZ45526.1 - 0.011 14.3 0.4 0.4 9.2 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (M) Methyltransf_23 PF13489.1 KEZ45527.1 - 6.2e-20 71.5 0.0 8.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45527.1 - 2.9e-10 40.4 0.0 6.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45527.1 - 3e-10 40.6 0.0 3.1e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45527.1 - 3.8e-10 39.5 0.0 3e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45527.1 - 1.2e-09 38.5 0.0 2.9e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ45527.1 - 2.2e-08 34.3 0.0 8.3e-08 32.5 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45527.1 - 1.6e-06 27.4 0.0 1.4e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KEZ45527.1 - 9.8e-06 24.7 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ45527.1 - 0.0001 22.3 0.0 0.00071 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ45527.1 - 0.00028 20.9 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KEZ45527.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KEZ45527.1 - 0.0095 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 KEZ45527.1 - 0.0098 15.0 0.0 0.02 13.9 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KEZ45527.1 - 0.023 13.8 0.0 0.049 12.7 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KEZ45527.1 - 0.052 13.0 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FmrO PF07091.6 KEZ45527.1 - 0.15 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MFS_1 PF07690.11 KEZ45528.1 - 1.4e-37 129.2 55.7 6.8e-36 123.6 37.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4066 PF13278.1 KEZ45528.1 - 2.1e-27 95.4 0.0 3.8e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEZ45528.1 - 4.5e-11 42.4 0.0 1.1e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family DUF899 PF05988.7 KEZ45529.1 - 3e-78 262.0 0.0 3.3e-78 261.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 KEZ45529.1 - 0.0078 15.8 0.0 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family TcpQ PF10671.4 KEZ45529.1 - 0.091 12.6 0.2 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q AAA PF00004.24 KEZ45530.1 - 0.0029 17.8 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ45530.1 - 0.0046 16.9 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.6 KEZ45530.1 - 0.018 14.9 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_10 PF12846.2 KEZ45530.1 - 0.038 13.4 0.1 0.085 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KEZ45530.1 - 0.047 13.1 0.0 0.27 10.6 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 KEZ45530.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 IL1_propep PF02394.11 KEZ45530.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Interleukin-1 propeptide AAA_14 PF13173.1 KEZ45530.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KEZ45531.1 - 1.1e-28 98.0 20.0 4.4e-10 39.0 0.1 7.8 9 0 0 9 9 9 4 WD domain, G-beta repeat NACHT PF05729.7 KEZ45531.1 - 1.6e-14 53.8 0.1 3.4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Abhydrolase_5 PF12695.2 KEZ45531.1 - 8.4e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 KEZ45531.1 - 0.0001 21.8 0.7 5 6.8 0.1 4.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 KEZ45531.1 - 0.00018 21.4 0.0 0.00058 19.7 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ45531.1 - 0.0002 21.0 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Nup160 PF11715.3 KEZ45531.1 - 0.00022 19.4 1.7 0.048 11.7 0.0 3.9 4 0 0 4 4 4 1 Nucleoporin Nup120/160 DUF676 PF05057.9 KEZ45531.1 - 0.00093 18.5 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_19 PF13245.1 KEZ45531.1 - 0.0025 17.5 0.0 0.0069 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain PQQ_2 PF13360.1 KEZ45531.1 - 0.0029 17.1 1.7 0.3 10.5 0.1 3.5 1 1 0 2 2 2 1 PQQ-like domain AAA_16 PF13191.1 KEZ45531.1 - 0.023 14.6 0.1 0.093 12.7 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain Cutinase PF01083.17 KEZ45531.1 - 0.048 13.3 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Cutinase Spt4 PF06093.8 KEZ45531.1 - 0.055 13.3 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger KxDL PF10241.4 KEZ45531.1 - 0.083 12.8 0.2 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein eIF2A PF08662.6 KEZ45531.1 - 0.11 12.1 0.1 1.1 8.9 0.0 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 KEZ45531.1 - 0.28 10.5 1.1 15 5.0 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature adh_short PF00106.20 KEZ45532.1 - 1.4e-13 51.1 0.4 2.7e-13 50.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ45532.1 - 1.5e-05 24.7 0.1 2.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEZ45532.1 - 0.0034 16.3 0.1 0.0047 15.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KEZ45532.1 - 0.036 14.1 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 KEZ45532.1 - 0.085 12.6 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KEZ45533.1 - 3.5e-12 46.0 0.8 1.4e-08 34.2 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEZ45533.1 - 6.5e-07 29.2 0.1 2.3e-06 27.5 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ45533.1 - 1.2e-06 27.6 0.1 2.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ45533.1 - 2e-05 24.5 0.2 0.00026 20.9 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KEZ45533.1 - 4.8e-05 22.4 0.0 0.0018 17.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ45533.1 - 6e-05 21.6 0.0 0.00063 18.3 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KEZ45533.1 - 0.00011 21.1 0.1 0.00043 19.2 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KEZ45533.1 - 0.00049 19.2 0.0 0.00088 18.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ45533.1 - 0.00092 19.5 0.1 0.013 15.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ45533.1 - 0.0014 18.7 0.0 0.0042 17.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ45533.1 - 0.006 15.7 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KEZ45533.1 - 0.019 13.9 0.0 2 7.2 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KEZ45533.1 - 0.073 11.6 0.1 6.8 5.1 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 KEZ45533.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 KEZ45533.1 - 0.28 10.7 1.6 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.17 KEZ45534.1 - 1.5e-160 534.5 0.3 1.7e-160 534.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ45534.1 - 0.00012 20.8 0.0 0.00026 19.8 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KEZ45534.1 - 0.011 15.0 0.1 0.38 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF4157 PF13699.1 KEZ45534.1 - 0.045 13.8 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Fungal_trans PF04082.13 KEZ45535.1 - 4.1e-09 35.6 0.5 7.5e-09 34.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45535.1 - 8e-05 22.4 8.0 0.00019 21.3 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF479 PF04336.7 KEZ45535.1 - 0.066 13.3 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF479 MFS_1 PF07690.11 KEZ45536.1 - 6.8e-23 80.9 24.5 5.2e-16 58.3 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_24 PF13578.1 KEZ45537.1 - 1.4e-06 29.1 0.1 3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45537.1 - 2.6e-06 27.9 0.0 4.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KEZ45537.1 - 0.002 17.4 0.1 0.0028 16.9 0.1 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_12 PF08242.7 KEZ45537.1 - 0.033 14.6 0.0 0.094 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF1383 PF07134.6 KEZ45537.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) DUF791 PF05631.9 KEZ45538.1 - 1.7e-11 43.4 3.8 2.6e-11 42.8 2.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KEZ45538.1 - 1.2e-05 24.1 7.7 1.8e-05 23.6 5.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4293 PF14126.1 KEZ45538.1 - 0.012 15.5 2.8 0.012 15.5 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF454 PF04304.8 KEZ45538.1 - 1.6 8.8 8.6 7 6.7 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF454) DUF4131 PF13567.1 KEZ45538.1 - 6 6.2 5.5 2.4 7.5 2.0 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) FTA2 PF13095.1 KEZ45539.1 - 1.2e-15 57.6 0.0 6.7e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Amidohydro_2 PF04909.9 KEZ45540.1 - 1.7e-39 136.0 0.1 2.2e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase SnoaL_4 PF13577.1 KEZ45541.1 - 2.9e-24 85.4 0.0 3.6e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain RPE65 PF03055.10 KEZ45542.1 - 3e-126 421.8 0.0 3.4e-126 421.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3341 PF11821.3 KEZ45542.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) OpcA_G6PD_assem PF10128.4 KEZ45542.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit Sugar_tr PF00083.19 KEZ45543.1 - 6e-80 269.0 21.5 7e-80 268.7 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45543.1 - 6e-20 71.2 36.9 5.2e-17 61.5 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ45543.1 - 3.8e-05 22.2 34.0 0.0012 17.2 4.1 3.7 2 2 1 4 4 4 3 MFS/sugar transport protein TRI12 PF06609.8 KEZ45543.1 - 0.00041 18.6 5.6 0.00042 18.6 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 KEZ45543.1 - 5.2 6.9 6.6 20 5.0 0.5 3.0 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Arylesterase PF01731.15 KEZ45544.1 - 0.0041 17.0 0.0 0.029 14.3 0.0 2.4 1 1 0 1 1 1 1 Arylesterase HET PF06985.6 KEZ45545.1 - 2.2e-33 115.3 0.0 3.6e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rabaptin PF03528.10 KEZ45546.1 - 0.034 14.0 1.0 0.064 13.1 0.1 1.8 2 1 0 2 2 2 0 Rabaptin DUF1843 PF08898.5 KEZ45546.1 - 1.1 9.3 3.7 22 5.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Aminotran_3 PF00202.16 KEZ45547.1 - 1.1e-58 198.6 0.0 1.4e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HET PF06985.6 KEZ45548.1 - 3.3e-22 79.1 0.0 6.1e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lactonase PF10282.4 KEZ45549.1 - 0.0071 15.4 0.0 0.039 13.0 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Amidase PF01425.16 KEZ45550.1 - 3.6e-74 250.2 2.7 2.5e-71 240.8 0.4 2.5 2 0 0 2 2 2 2 Amidase DUF4094 PF13334.1 KEZ45550.1 - 0.19 12.1 0.6 1.9 8.9 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) bZIP_1 PF00170.16 KEZ45550.1 - 0.23 11.4 11.2 1 9.3 7.8 2.0 1 1 0 1 1 1 0 bZIP transcription factor MFS_1 PF07690.11 KEZ45551.1 - 1.1e-23 83.6 52.6 1.3e-13 50.4 30.8 4.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Tmemb_14 PF03647.8 KEZ45551.1 - 0.015 15.6 0.0 0.015 15.6 0.0 3.6 4 0 0 4 4 4 0 Transmembrane proteins 14C Tropomyosin_1 PF12718.2 KEZ45552.1 - 9.9e-05 22.2 11.6 9.9e-05 22.2 8.1 2.3 2 0 0 2 2 2 1 Tropomyosin like Laminin_I PF06008.9 KEZ45552.1 - 0.0025 17.1 6.6 0.0025 17.1 4.5 1.6 2 0 0 2 2 2 1 Laminin Domain I zf-C4H2 PF10146.4 KEZ45552.1 - 0.0068 16.4 1.6 0.011 15.7 1.1 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein DUF3450 PF11932.3 KEZ45552.1 - 0.062 12.5 9.9 0.54 9.4 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Mod_r PF07200.8 KEZ45552.1 - 0.075 12.9 9.6 0.21 11.4 6.7 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Acetyltransf_6 PF13480.1 KEZ45552.1 - 0.1 12.5 0.2 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DivIVA PF05103.8 KEZ45552.1 - 0.24 11.4 9.1 0.89 9.6 3.0 2.5 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 KEZ45552.1 - 0.34 10.4 11.1 0.68 9.5 7.7 1.4 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 KEZ45552.1 - 0.45 10.2 13.5 1.1 9.0 9.4 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MalF_P2 PF14785.1 KEZ45552.1 - 1.1 9.1 5.3 2 8.2 1.6 2.2 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain APG6 PF04111.7 KEZ45552.1 - 2.4 7.0 13.6 7.8 5.4 8.9 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin PF00261.15 KEZ45552.1 - 2.7 7.0 20.1 0.012 14.6 6.8 2.3 3 0 0 3 3 3 0 Tropomyosin V_ATPase_I PF01496.14 KEZ45552.1 - 4.1 5.1 6.6 5.7 4.6 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.7 KEZ45552.1 - 4.7 7.6 6.5 0.69 10.3 0.8 2.4 2 1 0 2 2 2 0 SlyX FliJ PF02050.11 KEZ45552.1 - 7.7 6.5 15.4 0.12 12.3 0.5 3.1 2 1 1 3 3 3 0 Flagellar FliJ protein NACHT PF05729.7 KEZ45553.1 - 5.9e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain CCDC-167 PF15188.1 KEZ45553.1 - 0.0038 17.1 1.9 0.0038 17.1 1.3 2.4 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 KAP_NTPase PF07693.9 KEZ45553.1 - 0.014 14.4 0.0 0.031 13.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain INTS5_C PF14838.1 KEZ45553.1 - 0.066 11.5 2.0 0.066 11.4 0.2 1.9 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus AAA PF00004.24 KEZ45553.1 - 0.077 13.1 0.2 3.6 7.7 0.0 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Metal_resist PF13801.1 KEZ45553.1 - 1.5 8.8 4.5 3.6 7.6 0.2 3.4 5 0 0 5 5 5 0 Heavy-metal resistance Esterase_phd PF10503.4 KEZ45555.1 - 1.7e-16 60.1 0.0 2.3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEZ45555.1 - 5.7e-10 38.7 0.1 1e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ45555.1 - 0.0079 15.9 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ45555.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_10 PF00331.15 KEZ45556.1 - 7.2e-77 258.5 0.0 1.5e-76 257.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_1 PF00232.13 KEZ45556.1 - 0.006 14.8 0.1 0.0096 14.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3759 PF12585.3 KEZ45558.1 - 1.6e-36 124.1 2.6 1.9e-36 123.8 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) ABC2_membrane PF01061.19 KEZ45559.1 - 1.1e-80 269.7 52.6 2.5e-45 154.2 14.7 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KEZ45559.1 - 2.6e-38 131.4 0.1 2.2e-19 70.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KEZ45559.1 - 3.1e-23 81.3 0.1 9.7e-21 73.3 0.0 2.9 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KEZ45559.1 - 1.6e-08 33.9 30.4 3.9e-07 29.4 8.1 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 KEZ45559.1 - 2.1e-08 34.4 0.0 0.061 13.2 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KEZ45559.1 - 6.2e-07 29.5 0.2 0.00025 21.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KEZ45559.1 - 2.2e-06 26.9 0.2 0.00066 18.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ45559.1 - 8.4e-05 22.7 0.0 0.012 15.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KEZ45559.1 - 0.00099 18.7 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ45559.1 - 0.0026 17.2 0.1 0.016 14.7 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KEZ45559.1 - 0.0027 17.6 0.1 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEZ45559.1 - 0.0045 17.2 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEZ45559.1 - 0.0059 16.0 0.2 0.13 11.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KEZ45559.1 - 0.0079 15.9 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 KEZ45559.1 - 0.0097 15.5 0.2 0.039 13.5 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 KEZ45559.1 - 0.011 15.1 0.0 0.035 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KEZ45559.1 - 0.011 15.3 0.0 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 KEZ45559.1 - 0.012 15.0 0.0 0.73 9.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KEZ45559.1 - 0.018 15.5 0.0 0.99 9.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 KEZ45559.1 - 0.027 14.3 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KEZ45559.1 - 0.038 14.8 0.0 0.25 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KEZ45559.1 - 0.04 13.7 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KEZ45559.1 - 0.061 12.9 0.0 0.4 10.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ArgK PF03308.11 KEZ45559.1 - 0.085 11.6 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein MMR_HSR1 PF01926.18 KEZ45559.1 - 0.1 12.5 0.0 9.1 6.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 KEZ45559.1 - 0.15 12.2 0.0 14 5.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rootletin PF15035.1 KEZ45560.1 - 0.0042 17.0 0.0 0.0058 16.6 0.0 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Peptidase_S8 PF00082.17 KEZ45561.1 - 2.1e-47 161.6 1.9 3.5e-47 160.8 1.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KEZ45561.1 - 6.3e-20 71.5 0.2 2.2e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 Peptidase_M28 PF04389.12 KEZ45562.1 - 4.2e-30 104.8 0.1 6.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEZ45562.1 - 1.4e-20 72.8 1.2 2.7e-20 71.9 0.8 1.5 1 0 0 1 1 1 1 PA domain Glyco_hydro_114 PF03537.8 KEZ45563.1 - 1.9e-14 53.2 0.1 3.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 NACHT PF05729.7 KEZ45564.1 - 3.4e-05 23.5 0.0 8.6e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 KEZ45564.1 - 0.034 13.5 0.3 0.077 12.4 0.2 1.9 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 KEZ45564.1 - 0.14 12.3 0.3 0.59 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Alk_phosphatase PF00245.15 KEZ45565.1 - 9e-67 225.5 0.0 1.4e-66 224.9 0.0 1.3 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 KEZ45565.1 - 2.8e-07 30.0 0.1 4.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEZ45565.1 - 1.2e-06 28.0 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KEZ45565.1 - 0.0024 16.3 0.6 0.0065 14.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KEZ45565.1 - 0.067 12.0 0.2 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FTA4 PF13093.1 KEZ45565.1 - 0.26 10.6 0.0 0.41 10.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1795 PF08786.6 KEZ45566.1 - 0.04 13.7 0.3 0.093 12.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) DUF2562 PF10814.3 KEZ45566.1 - 0.24 11.3 4.7 0.19 11.6 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Prominin PF05478.6 KEZ45566.1 - 0.35 8.3 3.1 0.49 7.8 2.1 1.1 1 0 0 1 1 1 0 Prominin CENP-F_leu_zip PF10473.4 KEZ45566.1 - 0.69 9.7 20.3 8.6 6.2 5.0 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.6 KEZ45566.1 - 0.85 8.2 5.7 0.18 10.4 1.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF2422 PF10337.4 KEZ45566.1 - 1.6 7.4 5.5 2.4 6.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) APG6 PF04111.7 KEZ45566.1 - 1.6 7.7 15.0 0.6 9.1 6.9 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 5_nucleotid PF05761.9 KEZ45566.1 - 2.1 6.7 5.1 2.1 6.7 2.6 1.5 1 1 0 1 1 1 0 5' nucleotidase family Striatin PF08232.7 KEZ45566.1 - 3.7 7.8 12.9 13 6.1 7.9 2.4 2 1 0 2 2 2 0 Striatin family HlyD PF00529.15 KEZ45566.1 - 5.5 6.2 11.9 8.7 5.5 8.2 1.2 1 0 0 1 1 1 0 HlyD family secretion protein HSP70 PF00012.15 KEZ45567.1 - 3.3e-10 38.5 1.9 3.2e-06 25.3 0.1 3.0 3 0 0 3 3 3 3 Hsp70 protein YlaH PF14036.1 KEZ45569.1 - 1.1 9.4 4.9 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 YlaH-like protein UDPGT PF00201.13 KEZ45570.1 - 5.2e-08 31.8 0.0 2.9e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KEZ45570.1 - 0.042 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_hydro_3 PF00933.16 KEZ45572.1 - 2.5e-85 286.1 0.0 3.8e-85 285.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ45572.1 - 1.7e-61 207.6 0.8 1.4e-60 204.6 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ45572.1 - 1.7e-18 66.3 0.2 2.6e-17 62.4 0.1 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KEZ45572.1 - 1.9e-05 24.3 0.0 4.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain hemP PF10636.4 KEZ45572.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Hemin uptake protein hemP Sugar_tr PF00083.19 KEZ45573.1 - 2.8e-68 230.5 17.9 8.2e-68 229.0 9.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45573.1 - 5.9e-19 67.9 27.0 2.3e-13 49.5 9.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 KEZ45573.1 - 0.056 12.2 13.1 0.12 11.2 9.1 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Ni_hydr_CYTB PF01292.15 KEZ45573.1 - 1.4 8.2 7.2 0.37 10.1 1.9 2.2 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 GFO_IDH_MocA PF01408.17 KEZ45574.1 - 4.4e-21 75.6 0.1 3.9e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.17 KEZ45575.1 - 4.8e-19 69.0 0.0 9.9e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KEZ45575.1 - 0.041 14.2 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KEZ45577.1 - 8.5e-33 113.5 0.0 1.5e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEZ45577.1 - 8.9e-13 48.4 0.0 2.4e-12 47.1 0.0 1.7 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldl_recept_b PF00058.12 KEZ45577.1 - 1.1e-05 25.6 0.0 0.055 13.7 0.0 4.3 4 0 0 4 4 4 1 Low-density lipoprotein receptor repeat class B SGL PF08450.7 KEZ45577.1 - 2.5e-05 23.7 0.3 0.1 11.9 0.1 3.2 1 1 2 3 3 3 3 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KEZ45577.1 - 3e-05 23.7 0.1 0.034 14.0 0.0 4.5 4 0 0 4 4 4 1 NHL repeat Str_synth PF03088.11 KEZ45577.1 - 8.1e-05 22.5 0.0 0.23 11.4 0.0 3.8 4 0 0 4 4 3 1 Strictosidine synthase NAD_Gly3P_dh_N PF01210.18 KEZ45577.1 - 0.001 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KEZ45577.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KEZ45577.1 - 0.0014 18.0 0.0 0.0044 16.4 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KEZ45577.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 KEZ45577.1 - 0.019 15.3 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PQQ_3 PF13570.1 KEZ45577.1 - 0.034 14.4 3.5 0.063 13.5 0.1 3.3 4 0 0 4 4 4 0 PQQ-like domain NAD_binding_7 PF13241.1 KEZ45577.1 - 0.052 13.8 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KEZ45577.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PQQ PF01011.16 KEZ45577.1 - 0.27 10.8 0.1 0.27 10.8 0.0 3.5 5 0 0 5 5 5 0 PQQ enzyme repeat APH PF01636.18 KEZ45578.1 - 0.0015 18.3 0.3 0.0028 17.4 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family NAD_binding_1 PF00175.16 KEZ45579.1 - 2.6e-30 105.1 0.0 6.3e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEZ45579.1 - 2.7e-28 98.0 0.0 5.5e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KEZ45579.1 - 2.3e-21 75.3 0.0 4.1e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KEZ45579.1 - 4.4e-06 26.6 0.0 0.00048 20.0 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KEZ45579.1 - 0.0078 16.1 0.0 0.023 14.6 0.0 1.8 1 1 0 1 1 1 1 Siderophore-interacting FAD-binding domain p450 PF00067.17 KEZ45580.1 - 7.2e-65 219.2 0.0 8.9e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KEZ45581.1 - 2.5e-06 27.2 9.7 4.8e-06 26.3 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ45581.1 - 0.049 12.5 0.1 3.2 6.5 0.1 2.4 1 1 1 2 2 2 0 Fungal specific transcription factor domain His_Phos_1 PF00300.17 KEZ45582.1 - 1.2e-14 54.7 0.0 1.9e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.2 KEZ45583.1 - 9.5e-45 150.8 0.4 5.7e-18 65.0 0.1 4.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45583.1 - 4.9e-43 142.8 6.0 6.1e-09 35.2 0.0 7.8 7 1 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 KEZ45583.1 - 6.2e-30 100.2 4.2 2.1e-06 27.4 0.0 8.1 8 0 0 8 8 7 4 Ankyrin repeat Ank_5 PF13857.1 KEZ45583.1 - 8.3e-29 98.9 4.4 6.1e-09 35.8 0.2 6.1 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ45583.1 - 6.7e-24 83.8 0.5 2.2e-07 31.1 0.1 5.0 2 2 3 5 5 5 3 Ankyrin repeats (many copies) HET PF06985.6 KEZ45583.1 - 2e-21 76.6 8.9 5.3e-19 68.7 6.2 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 KEZ45583.1 - 9.2e-14 51.4 0.0 2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ45583.1 - 3.3e-09 36.9 2.1 7.3e-09 35.8 0.0 2.7 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ45583.1 - 1.6e-05 25.0 0.0 7.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KEZ45583.1 - 0.00097 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KEZ45583.1 - 0.0065 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 KEZ45583.1 - 0.007 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KEZ45583.1 - 0.0075 16.0 0.0 0.049 13.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain KAP_NTPase PF07693.9 KEZ45583.1 - 0.021 13.8 0.0 0.23 10.4 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.1 KEZ45583.1 - 0.021 15.6 0.0 0.18 12.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 KEZ45583.1 - 0.024 14.0 0.0 0.062 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KEZ45583.1 - 0.03 14.6 0.0 0.12 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ45583.1 - 0.031 13.8 0.1 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KEZ45583.1 - 0.041 13.5 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 KEZ45583.1 - 0.041 13.7 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ45583.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KEZ45583.1 - 0.058 13.1 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KEZ45583.1 - 0.071 13.3 0.0 0.26 11.5 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KEZ45583.1 - 0.081 12.0 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 KaiC Herpes_gE PF02480.11 KEZ45584.1 - 0.0011 17.3 0.0 0.0017 16.7 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KEZ45584.1 - 0.018 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Fic PF02661.13 KEZ45585.1 - 1.1e-16 61.2 0.0 3.3e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family Sugar_tr PF00083.19 KEZ45586.1 - 4.4e-58 196.9 12.1 1.2e-32 113.1 0.3 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45586.1 - 2.9e-07 29.5 8.7 2.9e-07 29.5 6.0 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ45587.1 - 1.1e-19 70.2 1.5 2.3e-19 69.3 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 KEZ45588.1 - 6.8e-34 117.0 0.0 1.1e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 KEZ45589.1 - 1.8e-18 66.7 0.0 4.6e-17 62.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ45589.1 - 6e-10 38.5 1.7 0.00098 18.1 1.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ45589.1 - 2.7e-06 27.2 3.1 9.3e-06 25.5 0.5 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEZ45589.1 - 3.4e-06 25.8 0.3 0.00019 20.0 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KEZ45589.1 - 3.5e-06 26.1 2.3 5.5e-06 25.4 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEZ45589.1 - 1.6e-05 24.0 0.1 3.1e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ45589.1 - 0.00017 21.5 0.9 0.00077 19.3 0.6 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEZ45589.1 - 0.00069 18.3 0.1 0.046 12.3 0.0 2.3 2 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 KEZ45589.1 - 0.0017 18.7 0.3 0.058 13.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ45589.1 - 0.004 16.1 0.2 0.82 8.5 0.4 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 KEZ45589.1 - 0.0044 16.1 1.2 0.0074 15.4 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 KEZ45589.1 - 0.011 14.6 0.0 0.028 13.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.17 KEZ45589.1 - 0.038 12.8 2.2 0.061 12.1 1.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KEZ45589.1 - 0.11 12.5 0.1 0.23 11.4 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-oxoacid_dh PF00198.18 KEZ45590.1 - 7.1e-30 103.9 0.0 1.2e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEZ45590.1 - 3.5e-15 55.4 1.7 6.2e-15 54.5 1.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Pkinase PF00069.20 KEZ45590.1 - 4.8e-12 45.5 0.0 8.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain VWA PF00092.23 KEZ45590.1 - 0.0023 17.6 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 KEZ45590.1 - 0.044 13.4 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain CorA PF01544.13 KEZ45591.1 - 1.8e-05 23.9 0.1 3.1e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein 60KD_IMP PF02096.15 KEZ45591.1 - 0.025 14.2 0.2 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein BTP PF05232.7 KEZ45591.1 - 3.8 7.3 6.6 0.56 9.9 0.6 2.1 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family dCMP_cyt_deam_1 PF00383.17 KEZ45592.1 - 1.4e-09 37.5 0.0 2.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Acetyltransf_1 PF00583.19 KEZ45593.1 - 3.5e-15 55.7 0.0 5.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEZ45593.1 - 1.7e-06 28.1 0.0 2.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEZ45593.1 - 4.4e-06 26.7 0.0 7.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEZ45593.1 - 2.2e-05 24.0 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KEZ45593.1 - 8.2e-05 22.7 0.0 0.00011 22.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KEZ45593.1 - 0.00031 20.5 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KEZ45593.1 - 0.00096 19.0 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain VCBS PF13517.1 KEZ45594.1 - 1.1e-29 102.5 51.0 1.3e-08 35.0 1.1 8.0 4 2 4 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEZ45594.1 - 1.4e-15 56.4 51.0 0.0032 17.1 2.2 9.1 9 0 0 9 9 9 8 FG-GAP repeat TcdB_toxin_midN PF12256.3 KEZ45594.1 - 1.1e-10 41.2 21.7 0.057 12.8 0.0 7.9 4 3 4 8 8 8 6 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.17 KEZ45594.1 - 2.3e-10 40.6 0.2 4e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KEZ45594.1 - 2.6e-10 40.7 0.0 5.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KEZ45594.1 - 1.9e-05 24.4 0.0 3.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SUKH-4 PF14435.1 KEZ45594.1 - 0.14 11.9 2.2 11 5.6 0.0 3.8 4 0 0 4 4 4 0 SUKH-4 immunity protein EF-hand_5 PF13202.1 KEZ45594.1 - 7.7 6.0 33.2 0.44 9.9 1.0 7.4 7 0 0 7 7 7 0 EF hand VCBS PF13517.1 KEZ45595.1 - 4e-59 196.8 93.9 1.2e-11 44.8 5.2 9.5 3 1 7 10 10 10 9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KEZ45595.1 - 3.3e-34 115.7 64.6 0.00032 20.2 0.6 10.7 10 0 0 10 10 10 10 FG-GAP repeat TcdB_toxin_midN PF12256.3 KEZ45595.1 - 2.8e-19 69.2 23.2 0.21 11.0 0.0 10.9 8 3 3 11 11 11 9 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 KEZ45595.1 - 1.2e-08 35.2 0.0 3.9e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ45595.1 - 1.9e-08 34.4 0.3 3.8e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BBS2_Mid PF14783.1 KEZ45595.1 - 0.0022 17.7 3.1 14 5.5 0.0 5.8 4 2 2 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Ank_2 PF12796.2 KEZ45597.1 - 2.1e-60 201.0 0.6 7.4e-19 67.8 0.2 7.2 2 1 7 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45597.1 - 1.4e-59 195.0 10.7 2.6e-08 33.2 0.0 12.0 10 1 1 11 11 11 7 Ankyrin repeat Ank_4 PF13637.1 KEZ45597.1 - 4.6e-44 148.0 6.2 5.2e-11 42.7 0.0 9.4 4 3 6 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ45597.1 - 3.6e-43 141.2 9.1 4.7e-06 26.3 0.0 12.3 13 1 1 14 14 14 7 Ankyrin repeat Ank_5 PF13857.1 KEZ45597.1 - 4e-39 131.7 15.0 1.1e-07 31.8 0.0 9.5 8 1 2 10 10 10 6 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ45597.1 - 4.6e-05 23.1 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ZZ PF00569.12 KEZ45597.1 - 0.0059 16.1 8.6 0.013 15.0 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type AAA_16 PF13191.1 KEZ45597.1 - 0.013 15.4 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain BLOC1_2 PF10046.4 KEZ45597.1 - 0.037 14.1 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Paramyx_P_V_C PF03210.8 KEZ45597.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Peptidase_C1_2 PF03051.10 KEZ45598.1 - 5.5e-151 503.0 0.0 6.4e-151 502.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KEZ45598.1 - 9.9e-10 38.6 0.2 3.1e-05 23.9 0.1 2.7 2 1 0 2 2 2 2 Papain family cysteine protease Glyco_hydro_76 PF03663.9 KEZ45599.1 - 2.7e-142 474.5 3.9 3.4e-142 474.2 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 AAA PF00004.24 KEZ45600.1 - 2.4e-20 73.0 0.0 4.5e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ45600.1 - 0.0059 16.7 0.2 0.17 12.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ45600.1 - 0.01 16.6 0.1 0.066 14.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KEZ45600.1 - 0.017 15.1 1.6 0.065 13.2 0.1 2.5 3 1 0 4 4 4 0 AAA ATPase domain Zot PF05707.7 KEZ45600.1 - 0.022 14.2 0.3 0.28 10.6 0.2 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) COesterase PF00135.23 KEZ45601.1 - 3.6e-88 296.5 0.0 5.4e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ45601.1 - 3.2e-09 36.6 0.0 1.3e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ45601.1 - 0.051 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ45601.1 - 0.052 12.7 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KEZ45601.1 - 0.11 11.1 0.0 0.49 8.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) MFS_1 PF07690.11 KEZ45602.1 - 1.1e-19 70.3 19.1 1.1e-19 70.3 13.3 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45602.1 - 4e-06 25.6 20.7 7.4e-05 21.5 13.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter FAA_hydrolase PF01557.13 KEZ45603.1 - 1.1e-43 149.3 0.0 1.2e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_S8 PF00082.17 KEZ45604.1 - 8e-47 159.7 0.3 8e-47 159.7 0.2 1.6 2 0 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 KEZ45604.1 - 6.1e-10 39.4 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) zf-C2HC PF01530.13 KEZ45605.1 - 0.92 9.2 7.8 32 4.3 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2HC type GCIP PF13324.1 KEZ45605.1 - 4.4 6.4 7.1 9.2 5.3 0.5 2.2 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting IIGP PF05049.8 KEZ45606.1 - 1.2e-23 83.6 0.0 1.6e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 KEZ45606.1 - 7.7e-05 22.6 0.0 0.00011 22.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KEZ45606.1 - 0.0022 17.5 0.2 0.23 10.9 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 KEZ45606.1 - 0.0028 17.6 0.1 0.0093 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KEZ45606.1 - 0.0044 17.4 0.0 0.0087 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KEZ45606.1 - 0.0046 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEZ45606.1 - 0.0058 15.8 0.0 0.0097 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KEZ45606.1 - 0.021 15.1 0.1 0.037 14.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KEZ45606.1 - 0.023 14.9 3.0 0.17 12.1 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 KEZ45606.1 - 0.026 15.3 0.6 0.064 14.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 KEZ45606.1 - 0.036 13.8 0.3 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KEZ45606.1 - 0.042 13.3 0.1 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.13 KEZ45606.1 - 0.079 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 KEZ45606.1 - 0.11 11.9 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 KEZ45606.1 - 0.15 11.8 0.2 0.15 11.8 0.1 2.0 2 1 1 3 3 2 0 Dynamin family Cu_amine_oxid PF01179.15 KEZ45607.1 - 3.9e-167 556.1 0.0 4.7e-167 555.9 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KEZ45607.1 - 4.6e-23 81.2 0.2 1e-22 80.0 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KEZ45607.1 - 1e-14 54.3 0.0 1.9e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Homeobox_KN PF05920.6 KEZ45608.1 - 4.3e-14 51.9 0.7 1.1e-13 50.5 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KEZ45608.1 - 1.9e-07 30.6 0.1 4.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KEZ45608.1 - 0.0022 18.2 7.9 0.9 10.0 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger HTH_Tnp_Tc5 PF03221.11 KEZ45608.1 - 0.034 13.9 0.4 2.3 8.0 0.0 3.6 3 1 0 3 3 3 0 Tc5 transposase DNA-binding domain HA PF03457.9 KEZ45608.1 - 0.054 13.6 0.1 0.22 11.6 0.1 2.1 1 0 0 1 1 1 0 Helicase associated domain zf-C2H2 PF00096.21 KEZ45608.1 - 0.38 11.1 14.3 1.1 9.6 0.4 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.7 KEZ45608.1 - 0.92 8.8 4.8 1.6 8.1 0.9 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding COesterase PF00135.23 KEZ45609.1 - 1.6e-88 297.7 0.0 7.7e-88 295.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ45609.1 - 2.2e-07 30.7 0.0 7.1e-06 25.7 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 KEZ45610.1 - 4e-54 183.8 8.2 9.7e-54 182.6 3.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45610.1 - 2.5e-18 65.9 10.2 3.9e-18 65.2 6.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ45610.1 - 0.00037 19.0 3.6 0.00037 19.0 2.5 2.1 2 1 0 3 3 3 1 MFS/sugar transport protein DUF1680 PF07944.7 KEZ45611.1 - 2.1e-111 372.7 0.0 3.2e-111 372.1 0.0 1.2 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) adh_short_C2 PF13561.1 KEZ45613.1 - 0.079 12.7 0.0 0.19 11.4 0.0 1.7 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase TPR_10 PF13374.1 KEZ45614.1 - 4.3e-53 175.8 5.2 4.7e-12 45.4 0.0 6.8 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ45614.1 - 7.2e-50 166.8 1.6 2.1e-17 62.7 0.0 5.5 2 1 3 5 5 5 4 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 KEZ45614.1 - 1.3e-26 93.4 0.0 1.2e-24 86.9 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II TPR_7 PF13176.1 KEZ45614.1 - 2e-12 45.9 4.6 0.0029 17.2 0.1 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ45614.1 - 3.4e-12 45.5 1.0 0.025 14.7 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ45614.1 - 5.2e-11 41.5 0.9 0.16 11.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ45614.1 - 1.2e-09 37.3 0.7 0.14 11.7 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ45614.1 - 2.1e-09 36.8 8.2 0.2 12.1 0.0 5.8 6 0 0 6 6 4 4 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KEZ45614.1 - 2.3e-09 36.5 0.3 8.3e-09 34.7 0.2 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_11 PF13414.1 KEZ45614.1 - 3.4e-09 36.2 1.2 0.0068 16.0 0.3 4.4 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 KEZ45614.1 - 3.9e-07 30.5 0.6 0.43 11.3 0.0 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ45614.1 - 5.4e-05 23.4 1.2 8.9 6.7 0.0 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ45614.1 - 7.5e-05 22.2 0.1 2.5 8.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ45614.1 - 0.00013 22.1 3.4 8.3 7.1 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ45614.1 - 0.00017 21.9 1.1 30 5.6 0.0 5.9 5 0 0 5 5 4 0 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ45614.1 - 0.0012 17.7 0.0 0.0029 16.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain PhdYeFM_antitox PF02604.14 KEZ45614.1 - 0.19 11.3 1.8 21 4.7 0.1 3.9 4 0 0 4 4 4 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Amidohydro_2 PF04909.9 KEZ45615.1 - 5.1e-43 147.5 0.1 6.5e-43 147.2 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase ADH_zinc_N PF00107.21 KEZ45616.1 - 5.2e-10 38.9 0.0 8.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ45616.1 - 2.6e-09 36.8 0.1 5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KEZ45616.1 - 0.052 14.4 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NACHT PF05729.7 KEZ45617.1 - 6.1e-12 45.5 0.0 1.8e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ45617.1 - 3e-06 27.3 1.7 8.9e-06 25.8 0.4 2.4 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KEZ45617.1 - 0.0015 17.9 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KEZ45617.1 - 0.0026 17.4 0.0 0.0063 16.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEZ45617.1 - 0.0045 17.1 0.2 0.028 14.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 KEZ45617.1 - 0.0045 17.1 0.1 0.14 12.3 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KEZ45617.1 - 0.0056 15.5 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PSDC PF12588.3 KEZ45617.1 - 0.012 15.1 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Phophatidylserine decarboxylase AAA_30 PF13604.1 KEZ45617.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEZ45617.1 - 0.043 13.7 0.1 7 6.5 0.0 3.4 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEZ45617.1 - 0.068 12.1 0.1 4.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MutS_III PF05192.13 KEZ45617.1 - 0.17 11.6 1.9 0.24 11.1 0.4 1.9 2 0 0 2 2 2 0 MutS domain III Methyltransf_23 PF13489.1 KEZ45618.1 - 1.5e-17 63.7 0.0 2.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45618.1 - 1.9e-12 47.4 0.0 3.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45618.1 - 1.8e-10 40.6 0.0 9.5e-10 38.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45618.1 - 2.3e-09 37.8 0.0 2.1e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45618.1 - 4.4e-09 36.7 0.0 2.1e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45618.1 - 9e-08 31.5 0.0 9e-07 28.2 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ45618.1 - 8e-06 26.1 0.0 1.9e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ45618.1 - 0.00029 19.9 0.0 0.0017 17.4 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KEZ45618.1 - 0.00035 19.9 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KEZ45618.1 - 0.026 13.7 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 KEZ45618.1 - 0.036 14.1 0.0 0.15 12.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KEZ45618.1 - 0.054 12.5 0.0 0.095 11.7 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 KEZ45618.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_PK PF05891.7 KEZ45618.1 - 0.13 11.4 0.1 0.23 10.7 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase FAD_binding_3 PF01494.14 KEZ45619.1 - 1e-20 74.1 0.0 5e-12 45.5 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KEZ45619.1 - 6.6e-10 38.4 2.7 0.00034 19.6 0.4 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ45619.1 - 1.3e-07 31.5 0.3 4.2e-07 29.9 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KEZ45619.1 - 1.8e-06 27.1 0.0 4.3e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KEZ45619.1 - 9e-06 24.7 2.1 1.8e-05 23.7 1.2 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KEZ45619.1 - 1.1e-05 24.2 0.2 0.0029 16.2 0.0 2.9 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KEZ45619.1 - 1.6e-05 25.0 0.1 5.4e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ45619.1 - 2e-05 23.2 0.5 0.019 13.4 0.7 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 KEZ45619.1 - 2.3e-05 24.6 0.1 0.0077 16.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ45619.1 - 5.9e-05 22.3 0.6 0.0099 14.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KEZ45619.1 - 0.00012 22.0 1.0 0.00075 19.4 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ45619.1 - 0.0082 15.2 0.4 0.02 13.9 0.3 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KEZ45619.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 120_Rick_ant PF12574.3 KEZ45619.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen GIDA PF01134.17 KEZ45619.1 - 0.021 13.7 0.5 0.064 12.1 0.1 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A MFS_1 PF07690.11 KEZ45620.1 - 1.9e-39 135.3 23.5 2.9e-39 134.7 16.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Bcl-2_3 PF15286.1 KEZ45620.1 - 0.027 14.9 0.6 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like DUF2649 PF10854.3 KEZ45620.1 - 1.6 8.9 6.4 0.52 10.4 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2649) Fungal_trans PF04082.13 KEZ45621.1 - 1.3e-27 96.3 0.1 2.9e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45621.1 - 4.6e-05 23.2 13.5 9e-05 22.3 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.13 KEZ45622.1 - 4.8e-119 397.3 0.1 3.7e-118 394.4 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase TPP_enzyme_N PF02776.13 KEZ45622.1 - 1.5e-25 89.6 0.5 1e-23 83.7 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEZ45622.1 - 7.3e-18 64.6 0.0 1.4e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ45622.1 - 6.2e-13 48.6 0.0 1.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain NMO PF03060.10 KEZ45622.1 - 3.1e-06 26.5 0.1 6.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 KEZ45622.1 - 4.8e-05 22.4 0.0 8.5e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KEZ45622.1 - 5.3e-05 22.2 0.0 0.00025 20.0 0.0 2.1 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KEZ45622.1 - 6.8e-05 22.0 0.0 0.33 9.9 0.0 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KEZ45622.1 - 0.00038 19.8 0.0 0.0017 17.6 0.0 2.0 2 1 1 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.16 KEZ45622.1 - 0.0072 15.3 0.0 0.025 13.5 0.0 1.6 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Aldedh PF00171.17 KEZ45623.1 - 7.7e-132 439.8 0.0 9.2e-132 439.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SPW PF03779.9 KEZ45623.1 - 0.027 13.8 0.2 0.067 12.5 0.1 1.6 1 0 0 1 1 1 0 SPW repeat APH PF01636.18 KEZ45624.1 - 8e-11 42.1 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ45624.1 - 2.9e-05 23.7 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KEZ45624.1 - 0.043 12.9 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 KEZ45624.1 - 0.063 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.2 KEZ45625.1 - 2e-35 120.9 0.0 1.2e-08 35.1 0.0 6.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ45625.1 - 1.3e-24 86.0 0.0 3.7e-07 30.4 0.0 6.4 6 1 2 8 8 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45625.1 - 5e-23 79.7 0.1 0.069 12.9 0.0 8.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 KEZ45625.1 - 2.5e-18 64.3 0.0 0.31 11.4 0.0 8.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KEZ45625.1 - 6.7e-13 48.4 2.3 0.0018 18.4 0.0 7.1 6 3 2 8 8 6 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 KEZ45625.1 - 2.7e-07 30.7 0.1 1.6e-06 28.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KEZ45625.1 - 4.9e-06 26.2 0.0 9.8e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ45625.1 - 0.00013 22.0 0.0 0.00065 19.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.2 KEZ45625.1 - 0.00015 21.7 2.7 0.0015 18.4 1.8 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KEZ45625.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF676 PF05057.9 KEZ45625.1 - 0.014 14.7 0.0 0.07 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) AAA PF00004.24 KEZ45625.1 - 0.018 15.2 0.0 0.13 12.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KEZ45625.1 - 0.046 12.7 0.8 1.4 7.8 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 KEZ45625.1 - 0.098 12.8 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 KEZ45625.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain FSH1 PF03959.8 KEZ45626.1 - 1.3e-34 119.4 0.0 1.5e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KEZ45626.1 - 0.0024 17.7 0.0 1.3 8.8 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ45626.1 - 0.0043 16.8 0.0 0.0063 16.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 KEZ45627.1 - 9.1e-81 271.0 0.0 2e-80 269.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KEZ45627.1 - 1.6e-64 216.9 0.2 3.4e-64 215.8 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 KEZ45627.1 - 3.4e-56 190.5 0.1 7.9e-56 189.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KEZ45627.1 - 4e-53 180.8 0.4 9.5e-53 179.5 0.3 1.7 1 1 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KEZ45627.1 - 3.2e-49 167.0 1.2 7.1e-49 165.9 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KEZ45627.1 - 8.9e-37 125.5 0.0 2.7e-36 124.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KEZ45627.1 - 5.9e-19 68.3 0.0 1.5e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KEZ45627.1 - 2.2e-17 62.8 0.1 6.3e-17 61.3 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ45627.1 - 3.2e-13 50.6 0.0 1.9e-12 48.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KEZ45627.1 - 2.7e-10 40.2 0.0 6.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45627.1 - 2.2e-09 37.0 0.0 6.4e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45627.1 - 2.2e-09 37.6 0.0 1e-08 35.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 KEZ45627.1 - 5.8e-08 32.4 0.1 1.3e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEZ45627.1 - 1.4e-07 31.6 0.0 5.4e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KEZ45627.1 - 1.7e-07 31.7 0.1 2e-06 28.3 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ45627.1 - 2.3e-05 24.6 0.0 0.00063 20.0 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45627.1 - 4e-05 22.8 0.0 9.9e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 KEZ45627.1 - 9.5e-05 21.4 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 KEZ45627.1 - 0.011 14.4 0.0 0.028 13.1 0.0 1.7 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 KEZ45627.1 - 0.18 11.2 0.0 0.43 9.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Transferase PF02458.10 KEZ45628.1 - 1e-10 40.6 0.0 4.7e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 Transferase family Aldo_ket_red PF00248.16 KEZ45629.1 - 4.4e-50 170.0 0.0 4.9e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GPAT_N PF14829.1 KEZ45629.1 - 0.11 12.1 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal LEA_5 PF00477.12 KEZ45631.1 - 0.037 14.2 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 Small hydrophilic plant seed protein Cytochrom_C_2 PF01322.15 KEZ45631.1 - 0.69 10.4 5.6 0.7 10.4 2.5 1.8 1 1 1 2 2 2 0 Cytochrome C' MFS_1 PF07690.11 KEZ45632.1 - 8.5e-29 100.3 36.8 8.5e-29 100.3 25.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 KEZ45633.1 - 1.2e-17 64.5 0.1 2.3e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEZ45633.1 - 1.1e-12 48.0 0.2 2.9e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AA_permease PF00324.16 KEZ45634.1 - 3.5e-127 424.6 37.1 3.9e-127 424.4 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KEZ45634.1 - 3.6e-32 111.4 45.2 4.8e-32 111.0 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KEZ45635.1 - 1.4e-25 89.7 59.4 2.8e-19 69.0 25.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45635.1 - 3.9e-10 38.9 8.1 3.9e-10 38.9 5.6 3.4 2 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 KEZ45635.1 - 0.0017 16.5 0.6 0.0039 15.3 0.4 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Cytomega_TRL10 PF06084.6 KEZ45635.1 - 1.2 8.9 5.4 15 5.3 0.1 2.6 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein Fungal_trans_2 PF11951.3 KEZ45637.1 - 0.00012 20.8 0.1 0.00016 20.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 KEZ45638.1 - 7.6e-35 120.4 2.1 1.2e-34 119.8 1.5 1.2 1 0 0 1 1 1 1 RTA1 like protein MMPL PF03176.10 KEZ45638.1 - 0.24 10.0 3.3 0.35 9.5 2.3 1.2 1 0 0 1 1 1 0 MMPL family DUF1223 PF06764.6 KEZ45639.1 - 1.9e-05 24.6 0.0 1.9e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Abhydrolase_6 PF12697.2 KEZ45640.1 - 8.3e-14 52.0 0.0 1.4e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ45640.1 - 5.3e-11 42.4 0.0 8.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ45640.1 - 0.00029 20.1 0.1 0.095 11.9 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KEZ45640.1 - 0.0018 18.0 0.1 0.0062 16.3 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KEZ45640.1 - 0.069 12.7 0.1 0.31 10.5 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KEZ45640.1 - 0.25 10.7 1.2 10 5.4 0.1 2.2 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BBE PF08031.7 KEZ45641.1 - 2.3e-11 43.4 0.2 4.1e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KEZ45641.1 - 7e-11 41.7 0.6 1.5e-10 40.7 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Cytokin-bind PF09265.5 KEZ45641.1 - 0.016 14.3 0.1 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Chromate_transp PF02417.10 KEZ45642.1 - 8.1e-49 165.4 36.0 1.4e-28 99.6 10.9 2.4 3 0 0 3 3 3 2 Chromate transporter Aconitase PF00330.15 KEZ45643.1 - 5.2e-62 209.8 0.0 3.3e-39 134.6 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KEZ45643.1 - 3.1e-06 27.3 0.0 6.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 KEZ45643.1 - 0.039 13.3 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus PEP_mutase PF13714.1 KEZ45644.1 - 1.6e-38 132.2 0.3 1.9e-38 132.0 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KEZ45644.1 - 8.7e-20 70.4 0.2 1.2e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Sua5_yciO_yrdC PF01300.13 KEZ45645.1 - 2.7e-12 46.2 0.0 3.5e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination MFS_1 PF07690.11 KEZ45646.1 - 1.6e-17 63.2 43.4 9.6e-12 44.2 8.1 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3754 PF12576.3 KEZ45646.1 - 0.73 9.4 5.9 0.2 11.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) MFS_1 PF07690.11 KEZ45647.1 - 1.2e-47 162.3 23.0 1e-42 146.1 8.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Aldo_ket_red PF00248.16 KEZ45648.1 - 2.8e-54 183.8 0.0 3.1e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRL PF13146.1 KEZ45648.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 TRL-like protein family AP_endonuc_2 PF01261.19 KEZ45648.1 - 0.081 12.1 0.0 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel ADH_zinc_N PF00107.21 KEZ45649.1 - 2.4e-31 107.9 0.6 3.8e-31 107.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ45649.1 - 2e-14 54.5 0.0 9.3e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ45649.1 - 8.9e-11 41.5 0.1 2.5e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KEZ45649.1 - 0.00029 20.8 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KEZ45649.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KEZ45649.1 - 0.038 13.5 0.2 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase p450 PF00067.17 KEZ45650.1 - 7e-71 239.1 0.0 8.5e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KEZ45651.1 - 2.3e-05 24.1 12.3 2.3e-05 24.1 8.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEZ45652.1 - 1.2e-38 132.7 21.6 1.2e-38 132.7 14.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 KEZ45652.1 - 0.066 13.3 0.0 0.066 13.3 0.0 3.6 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF308 PF03729.8 KEZ45652.1 - 0.56 10.2 11.7 0.31 11.0 2.7 3.4 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Piwi PF02171.12 KEZ45653.1 - 5.4e-78 262.0 0.0 1.2e-77 260.8 0.0 1.6 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 KEZ45653.1 - 1.4e-15 56.7 0.0 2.6e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KEZ45653.1 - 7.3e-15 54.0 0.5 1.5e-14 53.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Zip PF02535.17 KEZ45654.1 - 1.3e-54 185.3 9.9 1.6e-54 185.0 6.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter YniB PF14002.1 KEZ45654.1 - 0.71 9.3 3.7 0.31 10.4 0.6 1.8 2 0 0 2 2 2 0 YniB-like protein Tub_2 PF04525.7 KEZ45656.1 - 4.4e-23 81.6 0.1 5.2e-23 81.4 0.1 1.0 1 0 0 1 1 1 1 Tubby C 2 MFS_1 PF07690.11 KEZ45657.1 - 4e-16 58.6 79.1 4.6e-15 55.1 34.2 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ45657.1 - 2.7 6.3 32.8 3.4 5.9 12.5 2.6 1 1 1 2 2 2 0 MFS/sugar transport protein 7tm_4 PF13853.1 KEZ45658.1 - 0.0076 16.0 1.6 0.022 14.5 1.1 1.8 1 0 0 1 1 1 1 Olfactory receptor Dioxygenase_C PF00775.16 KEZ45659.1 - 7.5e-10 38.3 0.0 1.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Hemerythrin PF01814.18 KEZ45661.1 - 6.9e-10 39.2 0.0 9.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF953 PF06110.6 KEZ45662.1 - 1.8e-13 49.9 0.0 2.1e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 KEZ45662.1 - 0.00081 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF1446 PF07287.6 KEZ45663.1 - 4.7e-125 416.8 0.0 5.7e-125 416.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) GFA PF04828.9 KEZ45663.1 - 6.1e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CoA_transf_3 PF02515.12 KEZ45664.1 - 0.0015 17.8 0.0 0.64 9.2 0.0 3.1 2 1 1 3 3 3 2 CoA-transferase family III polyprenyl_synt PF00348.12 KEZ45665.1 - 7.5e-15 54.4 0.1 1.3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase HTH_psq PF05225.11 KEZ45665.1 - 0.032 13.7 0.2 12 5.5 0.1 3.1 3 0 0 3 3 3 0 helix-turn-helix, Psq domain DNA_pol3_a_NII PF11490.3 KEZ45665.1 - 0.13 11.9 0.5 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II p450 PF00067.17 KEZ45666.1 - 9e-38 129.9 0.2 1.5e-37 129.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KEZ45666.1 - 1.5e-20 73.5 4.0 1.8e-12 47.0 1.5 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KEZ45666.1 - 0.00034 20.5 0.3 0.00094 19.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ45666.1 - 0.0054 17.1 2.2 0.019 15.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ45666.1 - 0.0056 15.6 0.4 1.2 7.9 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 KEZ45666.1 - 0.022 13.6 1.3 0.7 8.7 0.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEZ45666.1 - 0.17 10.9 0.9 1.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase p450 PF00067.17 KEZ45667.1 - 2.4e-33 115.3 0.0 2.8e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3308 PF11751.3 KEZ45667.1 - 0.097 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3308) UnbV_ASPIC PF07593.7 KEZ45667.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 ASPIC and UnbV Trp_DMAT PF11991.3 KEZ45668.1 - 1.6e-86 290.7 0.0 1.8e-86 290.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.17 KEZ45669.1 - 4.9e-30 104.4 0.0 5.8e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.15 KEZ45671.1 - 1.2e-52 178.8 0.1 1.4e-52 178.6 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DHHW PF14286.1 KEZ45671.1 - 5.4 6.2 6.5 9.8 5.3 4.5 1.4 1 0 0 1 1 1 0 DHHW protein Methyltransf_2 PF00891.13 KEZ45672.1 - 4.6e-28 98.0 0.0 6.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_PK PF05891.7 KEZ45672.1 - 0.13 11.5 0.0 9.5 5.4 0.0 2.3 1 1 1 2 2 2 0 AdoMet dependent proline di-methyltransferase Alpha_kinase PF02816.13 KEZ45674.1 - 5e-31 107.8 0.2 1.5e-25 90.0 0.0 2.3 1 1 1 2 2 2 2 Alpha-kinase family VWA_2 PF13519.1 KEZ45674.1 - 1.6e-09 38.1 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KEZ45674.1 - 6.7e-05 22.6 0.1 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_43 PF04616.9 KEZ45675.1 - 4.7e-08 32.4 8.8 5.6e-06 25.6 2.2 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KEZ45675.1 - 7.8e-05 22.1 0.2 0.0007 19.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Transglut_core PF01841.14 KEZ45675.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily AAA_12 PF13087.1 KEZ45677.1 - 3.8e-22 78.6 0.0 6.1e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ45677.1 - 3.5e-14 52.9 0.0 8.5e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEZ45677.1 - 7e-05 22.4 0.0 0.0072 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ45677.1 - 9.3e-05 22.1 0.2 0.00099 18.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KEZ45677.1 - 0.0001 21.8 0.0 1.7 8.0 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KEZ45677.1 - 0.04 14.0 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEZ45677.1 - 0.13 12.6 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.24 KEZ45677.1 - 0.18 11.2 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Hemerythrin PF01814.18 KEZ45678.1 - 7.7e-12 45.5 11.7 7.7e-12 45.5 8.1 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain FlgN PF05130.7 KEZ45678.1 - 0.0049 17.1 2.3 0.0049 17.1 1.6 1.8 2 0 0 2 2 2 1 FlgN protein DUF1722 PF08349.6 KEZ45678.1 - 0.015 15.1 0.1 0.078 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) AAA_12 PF13087.1 KEZ45680.1 - 0.062 12.6 0.0 0.7 9.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Gemini_mov PF01708.11 KEZ45681.1 - 3.6 7.1 0.0 3.6 7.1 0.0 3.5 3 2 2 5 5 5 0 Geminivirus putative movement protein Tannase PF07519.6 KEZ45682.1 - 6.8e-61 206.4 0.0 1.2e-60 205.5 0.0 1.4 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEZ45682.1 - 0.018 14.9 0.3 0.079 12.8 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 KEZ45683.1 - 1.4e-22 79.8 37.4 4.2e-18 65.1 6.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KEZ45683.1 - 0.0099 13.9 0.5 0.0099 13.9 0.3 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF3487 PF11990.3 KEZ45683.1 - 0.39 10.1 0.0 0.39 10.1 0.0 4.2 4 2 2 6 6 6 0 Protein of unknown function (DUF3487) ABC_tran PF00005.22 KEZ45684.1 - 2.4e-39 134.7 0.1 1.1e-19 71.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KEZ45684.1 - 1.1e-13 51.2 10.4 1.1e-13 51.2 7.2 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 KEZ45684.1 - 2.9e-09 36.4 1.8 0.012 14.8 0.2 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KEZ45684.1 - 8.1e-08 31.8 0.0 0.012 15.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KEZ45684.1 - 3.8e-07 29.7 0.2 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 KEZ45684.1 - 4.4e-07 30.0 1.1 0.023 14.6 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 KEZ45684.1 - 2.3e-06 27.6 0.2 0.033 13.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_21 PF13304.1 KEZ45684.1 - 2.9e-06 27.4 0.0 1.1 9.2 0.0 4.1 3 1 1 4 4 4 1 AAA domain AAA_22 PF13401.1 KEZ45684.1 - 9.8e-06 25.7 2.0 0.11 12.5 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KEZ45684.1 - 1.9e-05 24.1 0.1 0.014 14.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ45684.1 - 2.6e-05 25.0 0.0 0.021 15.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEZ45684.1 - 7e-05 22.0 0.3 0.12 11.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 KEZ45684.1 - 7.4e-05 22.9 0.0 0.2 11.8 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 KEZ45684.1 - 8.8e-05 22.4 0.0 0.54 10.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 KEZ45684.1 - 0.0004 19.9 0.6 0.81 9.0 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 KEZ45684.1 - 0.00056 20.4 0.3 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 KEZ45684.1 - 0.00073 19.1 0.3 0.63 9.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KEZ45684.1 - 0.00079 19.1 0.4 0.4 10.3 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KEZ45684.1 - 0.0013 18.6 0.2 0.25 11.2 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.4 KEZ45684.1 - 0.002 16.7 1.0 0.81 8.2 0.1 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 KEZ45684.1 - 0.0032 16.4 1.2 0.29 9.9 0.0 2.6 3 0 0 3 3 2 1 Type II/IV secretion system protein NACHT PF05729.7 KEZ45684.1 - 0.0037 16.9 0.2 0.37 10.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.8 KEZ45684.1 - 0.006 15.5 0.2 0.83 8.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 KEZ45684.1 - 0.0073 15.1 1.9 0.86 8.4 0.3 3.0 2 1 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 KEZ45684.1 - 0.011 16.0 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ45684.1 - 0.015 15.4 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 KEZ45684.1 - 0.034 13.6 0.0 4.6 6.6 0.1 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.20 KEZ45684.1 - 0.041 13.3 0.4 0.48 9.8 0.1 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 KEZ45684.1 - 0.044 13.5 1.9 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 KEZ45684.1 - 0.057 13.7 0.1 3.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 KEZ45684.1 - 0.058 12.8 1.0 4 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 KEZ45684.1 - 0.11 11.5 0.2 13 4.7 0.0 2.3 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.10 KEZ45684.1 - 0.19 11.4 0.3 8.9 5.9 0.0 2.3 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.7 KEZ45684.1 - 0.2 10.9 0.2 8 5.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein ArgK PF03308.11 KEZ45684.1 - 0.21 10.3 2.2 4.5 5.9 0.1 2.3 2 0 0 2 2 2 0 ArgK protein DAP3 PF10236.4 KEZ45684.1 - 0.34 9.7 1.3 7.3 5.4 0.0 2.4 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Abhydrolase_6 PF12697.2 KEZ45685.1 - 1.2e-07 31.9 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 KEZ45686.1 - 8.4e-20 71.1 0.0 1.4e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45686.1 - 7e-10 38.6 0.0 4.1e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45686.1 - 1.4e-09 38.2 0.0 3.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45686.1 - 7.4e-09 36.1 0.1 1.8e-07 31.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45686.1 - 1.3e-08 35.2 0.0 6.1e-08 33.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ45686.1 - 0.0003 19.9 0.1 0.0019 17.2 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ45686.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ45686.1 - 0.0015 17.7 0.0 0.003 16.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KEZ45686.1 - 0.0023 17.9 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ45686.1 - 0.0025 17.1 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 KEZ45686.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KEZ45686.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 KEZ45686.1 - 0.045 12.8 0.0 0.53 9.3 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KEZ45687.1 - 1.5e-32 112.6 0.1 2.9e-32 111.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase ACC_epsilon PF13822.1 KEZ45687.1 - 0.027 14.8 0.4 0.055 13.8 0.3 1.5 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit MFS_1 PF07690.11 KEZ45688.1 - 1.5e-19 69.9 20.6 3.1e-19 68.9 14.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45688.1 - 4.6e-06 25.4 8.9 6e-05 21.7 6.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter PEMT PF04191.8 KEZ45688.1 - 1.6 8.9 7.1 0.13 12.4 0.5 2.4 3 1 0 3 3 3 0 Phospholipid methyltransferase Pkinase PF00069.20 KEZ45689.1 - 6.2e-36 123.8 0.0 1.2e-35 122.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45689.1 - 1.2e-21 76.9 0.0 1.8e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ45689.1 - 2.6e-05 23.3 0.0 0.0083 15.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.4 KEZ45689.1 - 0.025 13.9 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KEZ45689.1 - 0.11 12.2 0.8 0.36 10.5 0.5 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family PHO4 PF01384.15 KEZ45691.1 - 4.9e-112 373.7 13.9 5.8e-112 373.5 9.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family Chitin_bind_1 PF00187.14 KEZ45693.1 - 2.3e-12 46.6 81.8 1.6e-06 27.9 15.3 4.7 3 2 2 5 5 5 3 Chitin recognition protein NACHT PF05729.7 KEZ45694.1 - 0.0015 18.1 0.1 0.004 16.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Tropomyosin_1 PF12718.2 KEZ45694.1 - 0.11 12.3 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF3129 PF11327.3 KEZ45695.1 - 1.5e-45 155.3 6.6 1.5e-45 155.3 4.6 2.1 2 2 0 2 2 2 1 Protein of unknown function (DUF3129) Period_C PF12114.3 KEZ45695.1 - 1.4 8.4 4.1 2.2 7.8 2.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF3632 PF12311.3 KEZ45698.1 - 5.4e-22 78.4 0.0 7.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.6 KEZ45699.1 - 1.8e-23 83.2 0.0 7.1e-23 81.3 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Daxx PF03344.10 KEZ45699.1 - 3.6 5.9 20.3 5.2 5.4 14.1 1.1 1 0 0 1 1 1 0 Daxx Family Ank_2 PF12796.2 KEZ45700.1 - 3.1e-22 78.6 0.0 9.7e-11 41.8 0.0 3.9 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ45700.1 - 7.7e-16 56.6 3.4 0.0029 17.6 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.25 KEZ45700.1 - 3.7e-15 54.8 6.9 0.0019 17.9 0.0 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KEZ45700.1 - 7.6e-13 48.5 3.2 0.00013 22.4 0.0 6.0 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ45700.1 - 5.7e-09 35.9 0.4 2.3 8.5 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) WWE PF02825.15 KEZ45700.1 - 0.11 11.8 0.4 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 WWE domain Ferric_reduct PF01794.14 KEZ45701.1 - 7.7e-18 64.7 8.2 7.7e-18 64.7 5.7 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KEZ45701.1 - 8.4e-08 32.2 0.1 0.005 16.7 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 KEZ45701.1 - 3.9e-06 27.3 0.0 1.4e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 KEZ45701.1 - 1.8e-05 24.5 0.0 0.0037 17.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain Methyltransf_11 PF08241.7 KEZ45703.1 - 0.00026 21.4 0.0 0.00044 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45703.1 - 0.026 14.9 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ45703.1 - 0.036 13.7 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 KEZ45703.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.13 KEZ45703.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KEZ45703.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNA_bind_2 PF10133.4 KEZ45703.1 - 0.16 12.0 0.0 13 5.9 0.0 2.8 3 0 0 3 3 3 0 Predicted RNA-binding protein UDPG_MGDP_dh_N PF03721.9 KEZ45706.1 - 1.7e-49 167.6 0.0 3.5e-32 111.2 0.1 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 KEZ45706.1 - 2.9e-32 110.7 0.0 6.5e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 KEZ45706.1 - 2.6e-23 82.1 0.0 1.8e-18 66.6 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Atrophin-1 PF03154.10 KEZ45706.1 - 0.049 11.7 0.4 0.081 11.0 0.3 1.3 1 0 0 1 1 1 0 Atrophin-1 family Dioxygenase_C PF00775.16 KEZ45708.1 - 5.6e-10 38.7 0.1 1.2e-09 37.6 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase DUF4360 PF14273.1 KEZ45710.1 - 9.2e-13 48.2 0.0 1.2e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Acetyltransf_1 PF00583.19 KEZ45711.1 - 1.1e-12 47.7 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KEZ45711.1 - 3.9e-07 29.7 0.0 8.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KEZ45711.1 - 5.2e-05 23.3 0.0 8.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEZ45711.1 - 0.0021 18.1 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEZ45711.1 - 0.0057 16.8 0.0 0.007 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEZ45711.1 - 0.09 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_4 PF13637.1 KEZ45712.1 - 2.7e-15 56.3 0.9 2.2e-08 34.4 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEZ45712.1 - 8.2e-13 48.5 0.8 3.3e-05 24.1 0.2 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEZ45712.1 - 1.6e-12 47.2 3.1 4.7e-05 23.4 0.3 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45712.1 - 1.9e-09 36.8 5.2 0.00023 20.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KEZ45712.1 - 2.2e-09 36.6 3.8 0.0015 18.6 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 KEZ45712.1 - 6.8e-05 22.4 1.2 0.00048 19.7 0.3 2.6 2 1 0 2 2 2 1 KilA-N domain Fer2_BFD PF04324.10 KEZ45712.1 - 0.015 15.3 0.1 0.036 14.1 0.1 1.7 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Phage_mat-A PF03863.8 KEZ45712.1 - 0.024 13.6 0.1 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage maturation protein CENP-Q PF13094.1 KEZ45712.1 - 0.035 14.1 3.3 0.045 13.7 1.2 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fez1 PF06818.10 KEZ45712.1 - 0.082 12.9 3.2 0.16 11.9 2.2 1.4 1 0 0 1 1 1 0 Fez1 FYVE PF01363.16 KEZ45713.1 - 6.8e-22 77.1 23.0 5.5e-16 58.2 4.0 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 KEZ45713.1 - 0.00014 21.3 1.6 0.00056 19.4 1.1 2.0 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.7 KEZ45713.1 - 0.00025 21.0 7.5 0.022 14.8 0.1 3.0 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KEZ45713.1 - 0.00049 19.9 3.0 0.00049 19.9 2.1 3.4 3 0 0 3 3 3 2 AN1-like Zinc finger zf-C2H2_2 PF12756.2 KEZ45713.1 - 0.2 11.8 0.1 0.2 11.8 0.0 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) V_ATPase_I PF01496.14 KEZ45713.1 - 0.4 8.4 1.9 0.51 8.1 0.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CK_II_beta PF01214.13 KEZ45713.1 - 0.55 9.7 5.3 0.45 9.9 0.1 2.8 3 0 0 3 3 3 0 Casein kinase II regulatory subunit Sugar_tr PF00083.19 KEZ45714.1 - 3.7e-75 253.2 14.6 4.6e-75 252.9 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45714.1 - 2.6e-16 59.2 32.6 1e-15 57.3 16.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.4 KEZ45714.1 - 0.86 9.5 4.4 1.3 9.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Ldh_2 PF02615.9 KEZ45715.1 - 1.7e-97 326.1 0.0 1.9e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NAD_binding_7 PF13241.1 KEZ45716.1 - 4.1e-31 107.2 0.0 6.5e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KEZ45716.1 - 3.1e-26 90.4 0.0 4.6e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KEZ45716.1 - 4.1e-15 54.4 0.4 6.2e-15 53.8 0.3 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 KEZ45716.1 - 0.11 12.3 0.9 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 ThiF family Mito_fiss_reg PF05308.6 KEZ45717.1 - 0.0037 16.6 5.3 0.0037 16.6 3.7 2.5 3 0 0 3 3 3 1 Mitochondrial fission regulator DUF4139 PF13598.1 KEZ45718.1 - 5e-57 193.6 7.6 6.6e-42 143.9 0.0 2.9 2 1 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KEZ45718.1 - 2.2e-16 60.1 0.1 2.2e-16 60.1 0.0 3.9 3 1 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) Peptidase_S49_N PF08496.5 KEZ45718.1 - 0.79 9.5 7.7 2.2 8.0 5.3 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Methyltransf_10 PF05971.7 KEZ45719.1 - 7e-62 209.2 0.0 1.1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 KEZ45719.1 - 9e-05 23.0 0.0 0.00031 21.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KEZ45719.1 - 0.00033 20.0 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ45719.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ45719.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KEZ45719.1 - 0.028 14.0 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45719.1 - 0.054 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Sec20 PF03908.8 KEZ45719.1 - 0.081 12.6 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Sec20 Met_10 PF02475.11 KEZ45719.1 - 0.2 11.2 0.0 0.74 9.3 0.0 1.8 2 0 0 2 2 2 0 Met-10+ like-protein p450 PF00067.17 KEZ45720.1 - 9.6e-10 37.5 1.2 0.00024 19.7 0.1 3.0 3 0 0 3 3 3 3 Cytochrome P450 Ank PF00023.25 KEZ45721.1 - 1.4e-70 229.7 0.2 1e-11 44.0 0.0 9.2 8 1 0 8 8 8 7 Ankyrin repeat Ank_2 PF12796.2 KEZ45721.1 - 3.8e-63 209.8 0.0 1.1e-22 80.0 0.0 5.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ45721.1 - 1.8e-49 160.7 0.0 9.9e-07 28.4 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KEZ45721.1 - 3.2e-47 158.0 2.5 1e-08 35.4 0.0 8.5 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ45721.1 - 9.2e-42 140.1 9.9 3.4e-11 42.9 0.2 8.1 2 2 5 8 8 8 7 Ankyrin repeats (many copies) HET PF06985.6 KEZ45721.1 - 3.6e-23 82.2 4.0 8.5e-23 81.0 2.8 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.13 KEZ45722.1 - 3.4e-11 42.5 0.0 7.2e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45722.1 - 8.8e-08 31.9 8.8 1.4e-07 31.2 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-oxoacid_dh PF00198.18 KEZ45723.1 - 1.1e-76 257.1 0.1 1.4e-76 256.8 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KEZ45723.1 - 1.7e-18 66.0 0.5 3.6e-18 64.9 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KEZ45723.1 - 1.9e-12 46.5 0.3 1.9e-12 46.5 0.2 2.3 2 0 0 2 2 2 1 e3 binding domain DUF3614 PF12267.3 KEZ45723.1 - 0.0041 17.4 0.2 0.012 15.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3614) Sec7 PF01369.15 KEZ45724.1 - 2.2e-67 226.4 3.3 4.5e-67 225.4 0.6 2.6 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 KEZ45724.1 - 3.2e-49 166.5 0.7 3.2e-49 166.5 0.5 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KEZ45724.1 - 8.5e-31 105.3 5.1 4.6e-30 102.9 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Fip1 PF05182.8 KEZ45725.1 - 1.9e-20 71.8 1.2 3.8e-20 70.8 0.8 1.5 1 0 0 1 1 1 1 Fip1 motif Cytomega_UL20A PF05984.7 KEZ45725.1 - 0.05 13.7 3.9 0.12 12.6 2.7 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Nucleoporin_FG PF13634.1 KEZ45726.1 - 1e-31 109.4 138.0 1.6e-14 54.1 30.8 4.0 2 1 2 4 4 4 3 Nucleoporin FG repeat region Spc7 PF08317.6 KEZ45726.1 - 0.016 13.8 0.8 1.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KEZ45726.1 - 0.064 13.0 1.6 0.31 10.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 KEZ45726.1 - 0.087 12.4 0.0 0.087 12.4 0.0 2.5 2 1 0 2 2 2 0 IncA protein DUF972 PF06156.8 KEZ45726.1 - 3.4 8.0 5.7 3.3 8.0 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) RNA_pol_3_Rpc31 PF11705.3 KEZ45727.1 - 2e-36 126.0 5.7 2.4e-36 125.8 3.9 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2076 PF09849.4 KEZ45727.1 - 3.3 7.7 9.4 5.7 6.9 6.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Sulfate_transp PF00916.15 KEZ45728.1 - 2.9e-64 216.7 8.9 8.1e-64 215.3 6.2 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEZ45728.1 - 1.1e-26 92.3 0.3 1.1e-26 92.3 0.2 3.3 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEZ45728.1 - 3.8e-08 32.7 0.0 6.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain DUF2570 PF10828.3 KEZ45729.1 - 0.36 10.4 5.0 0.52 9.9 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) AbiH PF14253.1 KEZ45729.1 - 0.99 8.9 4.5 2.3 7.7 3.1 1.5 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH Dynamin_N PF00350.18 KEZ45729.1 - 1.2 8.9 5.9 3.9 7.2 0.0 2.2 1 1 0 2 2 2 0 Dynamin family DUF4404 PF14357.1 KEZ45729.1 - 1.4 9.3 4.7 22 5.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Borrelia_P83 PF05262.6 KEZ45729.1 - 2.6 6.2 7.7 3.2 5.9 5.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein N2227 PF07942.7 KEZ45732.1 - 1.1e-64 218.0 0.0 1.5e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.7 KEZ45732.1 - 5.2e-06 26.8 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45732.1 - 0.002 18.5 0.0 0.0093 16.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ45732.1 - 0.015 15.0 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ImcF-related_N PF14331.1 KEZ45732.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.4 1 1 0 1 1 1 0 ImcF-related N-terminal domain Methyltransf_31 PF13847.1 KEZ45732.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2284 PF10050.4 KEZ45733.1 - 2.4e-05 23.9 133.6 1.4 8.4 0.9 15.4 15 0 0 15 15 15 15 Predicted metal-binding protein (DUF2284) DUF433 PF04255.9 KEZ45733.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Cyt-b5 PF00173.23 KEZ45734.1 - 6.9e-17 61.0 0.4 5.9e-10 38.8 0.1 4.0 4 0 0 4 4 4 3 Cytochrome b5-like Heme/Steroid binding domain DUF2802 PF10975.3 KEZ45735.1 - 0.06 13.1 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) RWP-RK PF02042.10 KEZ45735.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 RWP-RK domain TPR_16 PF13432.1 KEZ45736.1 - 1.4e-11 44.6 3.2 8.2e-10 39.0 1.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ45736.1 - 4.1e-10 39.1 6.6 4.5e-08 32.6 0.2 5.4 5 1 1 6 6 6 2 TPR repeat TPR_2 PF07719.12 KEZ45736.1 - 1e-09 37.5 3.2 0.002 17.8 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ45736.1 - 2.1e-08 33.4 0.1 0.018 14.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ45736.1 - 2.1e-05 24.3 8.0 0.0034 17.3 1.1 3.9 3 1 2 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ45736.1 - 2.8e-05 24.3 3.2 0.0039 17.6 0.5 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ45736.1 - 0.00095 18.7 7.6 0.0098 15.6 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ45736.1 - 0.0041 16.9 0.6 0.016 15.0 0.4 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ45736.1 - 0.036 14.4 0.1 0.036 14.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ45736.1 - 0.04 13.7 1.1 1.3 9.0 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Sigma70_ner PF04546.8 KEZ45736.1 - 0.056 13.0 2.4 6 6.4 1.1 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_6 PF13174.1 KEZ45736.1 - 0.25 11.8 2.1 24 5.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HSP70 PF00012.15 KEZ45737.1 - 1e-06 26.9 0.0 1.9e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ45737.1 - 0.021 13.4 0.4 0.039 12.5 0.1 1.5 2 0 0 2 2 2 0 MreB/Mbl protein XAP5 PF04921.9 KEZ45738.1 - 1.8e-80 269.9 0.3 2.9e-80 269.2 0.2 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator GYF PF02213.11 KEZ45739.1 - 1.5e-19 69.2 2.0 2.4e-19 68.6 0.0 2.3 2 0 0 2 2 2 1 GYF domain ABC_tran PF00005.22 KEZ45741.1 - 4.4e-48 163.0 0.3 5.7e-25 88.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KEZ45741.1 - 2.4e-18 66.2 0.2 2.8e-07 30.0 0.0 3.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ45741.1 - 1.7e-17 64.3 0.1 0.00092 19.2 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KEZ45741.1 - 6.7e-10 38.3 0.1 0.0015 18.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ45741.1 - 1.8e-08 35.2 0.0 0.0021 18.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEZ45741.1 - 2.3e-08 34.2 0.0 0.00022 21.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KEZ45741.1 - 9.6e-08 32.5 10.4 0.00018 21.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 KEZ45741.1 - 1.3e-07 30.9 0.0 0.0009 18.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 KEZ45741.1 - 3e-07 30.5 0.0 0.0073 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KEZ45741.1 - 4.9e-07 29.7 0.0 0.0049 16.8 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 KEZ45741.1 - 1.4e-06 27.9 0.2 0.26 10.7 0.0 3.9 4 1 0 4 4 4 2 AAA-like domain AAA_15 PF13175.1 KEZ45741.1 - 1.7e-06 27.3 3.1 0.16 10.9 0.0 4.3 3 2 1 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 KEZ45741.1 - 2e-06 27.7 0.1 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KEZ45741.1 - 3.9e-06 27.2 0.3 0.13 12.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 KEZ45741.1 - 5.4e-06 26.3 0.0 0.001 18.8 0.0 2.8 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KEZ45741.1 - 6e-06 26.7 0.1 0.058 13.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 KEZ45741.1 - 1.1e-05 25.1 0.0 0.022 14.6 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KEZ45741.1 - 2.2e-05 24.6 0.0 0.46 10.6 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KEZ45741.1 - 3.4e-05 23.5 0.1 0.43 10.2 0.0 3.1 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KEZ45741.1 - 6.1e-05 21.9 0.3 0.24 10.1 0.0 2.4 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 KEZ45741.1 - 6.5e-05 23.0 0.0 0.54 10.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase PduV-EutP PF10662.4 KEZ45741.1 - 0.0001 21.8 1.0 0.11 12.0 0.0 3.2 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KEZ45741.1 - 0.00013 21.6 0.0 0.069 12.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 KEZ45741.1 - 0.00015 21.6 0.0 1.5 8.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KEZ45741.1 - 0.00035 20.3 0.0 1.3 8.7 0.0 3.0 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 KEZ45741.1 - 0.00049 20.1 4.2 0.82 9.6 0.0 4.6 5 0 0 5 5 5 1 AAA ATPase domain cobW PF02492.14 KEZ45741.1 - 0.00097 18.6 0.9 2.4 7.5 0.0 3.7 5 0 0 5 5 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 KEZ45741.1 - 0.001 17.6 5.9 1.3 7.4 0.0 4.3 4 1 0 4 4 4 2 AAA domain DUF87 PF01935.12 KEZ45741.1 - 0.0015 18.3 2.9 0.85 9.3 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KEZ45741.1 - 0.0025 17.3 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KEZ45741.1 - 0.0053 16.3 0.1 7 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KEZ45741.1 - 0.0059 16.0 0.0 4.9 6.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain Septin PF00735.13 KEZ45741.1 - 0.0059 15.6 0.0 0.8 8.6 0.0 2.6 2 0 0 2 2 2 1 Septin FtsK_SpoIIIE PF01580.13 KEZ45741.1 - 0.011 15.2 0.4 4.9 6.5 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KEZ45741.1 - 0.013 15.0 0.0 6.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MutS_V PF00488.16 KEZ45741.1 - 0.019 14.3 0.1 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 MutS domain V T2SE PF00437.15 KEZ45741.1 - 0.027 13.3 0.1 3 6.6 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 KEZ45741.1 - 0.033 13.3 0.1 2.4 7.2 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 KEZ45741.1 - 0.038 13.5 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family 2OG-FeII_Oxy_4 PF13661.1 KEZ45741.1 - 0.041 13.5 0.1 0.09 12.4 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Rad17 PF03215.10 KEZ45741.1 - 0.048 12.3 0.0 3.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Vitellogenin_N PF01347.17 KEZ45741.1 - 0.059 11.5 1.9 0.083 11.1 1.3 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region AAA_19 PF13245.1 KEZ45741.1 - 0.16 11.7 1.7 6.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain DAP3 PF10236.4 KEZ45741.1 - 0.66 8.8 6.6 4.7 6.0 0.5 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Glyco_hydro_61 PF03443.9 KEZ45742.1 - 6e-60 202.7 0.2 7.4e-60 202.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PKD_channel PF08016.7 KEZ45743.1 - 2.3e-08 32.8 19.0 6.2e-06 24.9 6.1 2.3 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.26 KEZ45743.1 - 0.053 12.7 26.9 3.2 6.9 18.6 2.4 1 1 0 1 1 1 0 Ion transport protein AAA PF00004.24 KEZ45744.1 - 2.9e-15 56.6 0.0 9.4e-15 54.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KEZ45744.1 - 0.00015 21.4 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEZ45744.1 - 0.0037 17.3 1.0 0.09 12.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ45744.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Macro PF01661.16 KEZ45745.1 - 5.4e-41 139.2 0.0 7e-41 138.8 0.0 1.1 1 0 0 1 1 1 1 Macro domain Peptidase_S46 PF10459.4 KEZ45746.1 - 0.088 11.2 4.3 0.13 10.6 3.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Fungal_trans PF04082.13 KEZ45747.1 - 1.3e-09 37.3 0.0 2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45747.1 - 1.1e-05 25.2 8.0 1.8e-05 24.5 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KEZ45748.1 - 9e-76 255.2 16.4 1e-75 255.0 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45748.1 - 2.8e-13 49.3 26.1 3.6e-11 42.3 13.5 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 KEZ45749.1 - 1.3e-09 37.9 0.0 5.7e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ45749.1 - 3.6e-06 26.8 0.0 5.8e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ45749.1 - 9e-05 22.4 0.4 0.00022 21.1 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ45749.1 - 0.00016 20.9 0.0 0.056 12.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase_phd PF10503.4 KEZ45749.1 - 0.013 14.7 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Sulfate_transp PF00916.15 KEZ45750.1 - 2.2e-50 171.2 7.7 2.2e-50 171.2 5.3 1.9 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KEZ45750.1 - 2.4e-29 100.8 2.6 9.3e-29 98.9 1.8 2.1 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KEZ45750.1 - 3.1e-17 62.0 0.0 6.8e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KEZ45750.1 - 0.0096 15.9 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 STAS domain Thiolase_N PF00108.18 KEZ45751.1 - 1.3e-69 234.1 0.3 3.2e-69 232.8 0.1 1.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KEZ45751.1 - 6.9e-41 138.5 1.1 1.7e-40 137.2 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 KEZ45751.1 - 0.062 13.3 0.1 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_cc PF11790.3 KEZ45752.1 - 7.3e-65 218.7 0.0 8.9e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SIR2 PF02146.12 KEZ45755.1 - 4.4e-20 72.1 0.0 1.7e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 Sir2 family CHCH PF06747.8 KEZ45756.1 - 3.5e-06 26.7 4.9 5.9e-06 26.0 3.4 1.4 1 0 0 1 1 1 1 CHCH domain Rtf2 PF04641.7 KEZ45756.1 - 8.6 5.4 9.9 0.59 9.2 2.1 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger TPK_B1_binding PF04265.9 KEZ45757.1 - 5.1e-21 74.1 0.0 1.1e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.11 KEZ45757.1 - 8.2e-19 67.3 0.0 7.7e-18 64.2 0.0 2.3 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, catalytic domain NACHT PF05729.7 KEZ45757.1 - 1.4e-08 34.5 0.0 3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ45757.1 - 0.00035 20.6 0.4 0.016 15.1 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEZ45757.1 - 0.0005 20.2 0.1 0.0026 17.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KEZ45757.1 - 0.0044 17.3 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 KEZ45757.1 - 0.012 14.4 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 KEZ45757.1 - 0.029 15.1 0.0 0.16 12.7 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEZ45757.1 - 0.037 13.4 0.1 0.22 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 KEZ45757.1 - 0.054 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KEZ45757.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KEZ45757.1 - 0.1 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 KEZ45757.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KEZ45757.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 KEZ45757.1 - 0.21 11.0 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 3HCDH_N PF02737.13 KEZ45758.1 - 3.4e-29 101.7 0.0 6.9e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KEZ45758.1 - 6.8e-19 68.0 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.19 KEZ45758.1 - 0.00028 19.9 0.4 0.00071 18.5 0.2 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 KEZ45758.1 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KEZ45758.1 - 0.00038 20.2 0.1 0.00077 19.2 0.1 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 KEZ45758.1 - 0.00059 19.7 0.0 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 KEZ45758.1 - 0.00077 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ45758.1 - 0.004 17.1 0.1 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Herpes_ICP4_C PF03585.9 KEZ45758.1 - 0.0048 15.6 0.0 0.0083 14.8 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus ICP4-like protein C-terminal region Lycopene_cycl PF05834.7 KEZ45758.1 - 0.0083 15.0 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KEZ45758.1 - 0.0087 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain XdhC_C PF13478.1 KEZ45758.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.12 KEZ45758.1 - 0.021 15.2 0.0 0.068 13.6 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KEZ45758.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Rossmann-like PF10727.4 KEZ45758.1 - 0.096 12.4 0.1 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Rossmann-like domain Pyr_redox_2 PF07992.9 KEZ45758.1 - 0.097 12.5 0.1 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 KEZ45760.1 - 3.3e-38 131.2 25.9 3.3e-38 131.2 18.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45760.1 - 2.4e-12 46.1 20.1 3.6e-12 45.6 13.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 KEZ45760.1 - 0.0096 15.7 1.0 0.0096 15.7 0.7 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF4231 PF14015.1 KEZ45760.1 - 8.3 6.4 10.2 0.43 10.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) AAA PF00004.24 KEZ45761.1 - 6.4e-19 68.4 0.0 1.2e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ45761.1 - 0.00096 19.2 0.3 0.075 13.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ45761.1 - 0.0029 18.4 0.1 0.017 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ45761.1 - 0.0045 16.9 0.3 0.016 15.2 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KEZ45761.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain CENP-W PF15510.1 KEZ45761.1 - 0.04 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Centromere kinetochore component W AAA_5 PF07728.9 KEZ45761.1 - 0.061 13.0 0.0 0.44 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) tRNA-synt_1b PF00579.20 KEZ45763.1 - 2.8e-32 112.0 0.0 3.7e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) 2OG-FeII_Oxy PF03171.15 KEZ45764.1 - 3e-06 27.4 0.0 4.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KEZ45764.1 - 5.7e-06 26.8 0.0 9.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 KEZ45765.1 - 4.7e-43 147.2 41.6 8.5e-43 146.4 28.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ45765.1 - 2.5e-18 65.8 13.2 2.5e-18 65.8 9.2 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KEZ45765.1 - 6.2e-06 24.6 9.1 6.2e-06 24.6 6.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KEZ45766.1 - 2.7e-43 148.0 51.7 2.7e-43 148.0 35.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ45766.1 - 3.9e-15 55.0 16.4 7.2e-15 54.2 11.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KEZ45766.1 - 6.9e-12 44.6 13.4 6.9e-12 44.6 9.3 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter QCR10 PF09796.4 KEZ45766.1 - 0.11 12.1 4.6 0.8 9.4 0.1 3.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) NACHT PF05729.7 KEZ45768.1 - 2.4e-07 30.5 0.0 1.2e-06 28.2 0.0 2.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ45768.1 - 9.8e-06 25.7 0.0 0.00011 22.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEZ45768.1 - 0.00043 19.8 0.2 0.0066 15.9 0.0 2.7 2 1 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 KEZ45768.1 - 0.00067 19.7 4.2 0.0038 17.2 0.2 3.4 2 2 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 KEZ45768.1 - 0.0041 16.6 0.0 0.16 11.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KEZ45768.1 - 0.011 16.0 0.0 0.06 13.6 0.0 2.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ45768.1 - 0.011 15.9 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KEZ45768.1 - 0.011 16.0 2.4 0.09 13.0 0.0 3.1 3 1 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 KEZ45768.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ45768.1 - 0.032 15.0 1.3 0.23 12.2 0.3 3.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KEZ45768.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.8 1 1 1 2 2 1 0 AAA domain p450 PF00067.17 KEZ45769.1 - 0.00097 17.7 0.1 0.0019 16.7 0.1 1.6 1 1 0 1 1 1 1 Cytochrome P450 Asp_protease PF09668.5 KEZ45769.1 - 0.045 13.3 0.1 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease PHO4 PF01384.15 KEZ45770.1 - 1.4e-99 332.8 16.9 1.6e-99 332.6 11.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family Ank_2 PF12796.2 KEZ45771.1 - 2.6e-42 143.0 2.9 5.7e-15 55.4 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45771.1 - 1.3e-37 125.7 20.2 5.8e-08 32.1 0.1 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KEZ45771.1 - 1.3e-31 107.8 9.2 4e-07 30.0 0.4 7.6 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ45771.1 - 1.1e-28 96.4 9.3 0.0014 18.6 0.0 8.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 KEZ45771.1 - 1.4e-24 85.9 2.7 9.2e-08 32.4 0.0 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ45771.1 - 1.4e-07 31.3 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ45771.1 - 0.012 15.5 0.4 0.06 13.3 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 KEZ45771.1 - 0.47 9.3 0.4 2.3 7.1 0.0 2.0 1 1 0 2 2 2 0 KAP family P-loop domain DUF676 PF05057.9 KEZ45772.1 - 1.5e-07 30.9 0.0 2.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KEZ45772.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KEZ45772.1 - 0.0053 16.6 0.3 0.016 15.1 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.9 KEZ45772.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_8 PF06259.7 KEZ45772.1 - 0.043 13.3 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_5 PF12695.2 KEZ45772.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Whi5 PF08528.6 KEZ45773.1 - 1.3e-09 37.4 0.0 2.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like HET PF06985.6 KEZ45774.1 - 1.1e-13 51.4 0.0 2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_3 PF00933.16 KEZ45775.1 - 6.7e-89 297.8 0.1 1e-88 297.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ45775.1 - 6.3e-61 205.7 0.3 1.7e-60 204.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ45775.1 - 1e-25 89.4 0.3 2e-25 88.4 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Cuticle_1 PF08140.6 KEZ45775.1 - 0.032 14.0 0.1 0.097 12.5 0.0 1.9 1 0 0 1 1 1 0 Crustacean cuticle protein repeat DUF3531 PF12049.3 KEZ45775.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) Myb_DNA-bind_3 PF12776.2 KEZ45776.1 - 2.3e-22 79.4 0.2 4.1e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Zip PF02535.17 KEZ45777.1 - 0.094 11.7 2.2 0.11 11.4 1.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 KEZ45777.1 - 3.7 5.6 5.6 4.5 5.4 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_18 PF00704.23 KEZ45778.1 - 2.1e-65 221.4 0.0 3.3e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.13 KEZ45779.1 - 3.3e-21 75.3 0.8 1.5e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45779.1 - 1.2e-08 34.7 9.9 2.7e-08 33.6 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KEZ45781.1 - 4e-25 88.6 0.0 6.3e-25 87.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ45781.1 - 5.4e-12 45.2 0.1 5.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ45781.1 - 1.3e-06 28.6 0.1 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ45781.1 - 4.6e-06 25.7 2.8 6.7e-06 25.1 1.4 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KEZ45781.1 - 8.8e-06 24.4 0.7 0.00057 18.4 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KEZ45781.1 - 1.2e-05 25.2 0.1 5.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEZ45781.1 - 7.2e-05 21.8 0.1 0.00023 20.1 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KEZ45781.1 - 9.5e-05 22.3 0.3 0.0003 20.7 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ45781.1 - 0.00026 20.1 0.1 0.00045 19.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 KEZ45781.1 - 0.00035 19.3 0.3 0.0077 14.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase SE PF08491.5 KEZ45781.1 - 0.0022 16.8 0.1 0.01 14.7 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 KEZ45781.1 - 0.0025 16.8 0.1 1.3 7.8 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KEZ45781.1 - 0.0097 15.9 0.0 0.026 14.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ45781.1 - 0.011 14.8 0.7 0.016 14.3 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEZ45781.1 - 0.02 13.9 1.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Rossmann-like PF10727.4 KEZ45781.1 - 0.042 13.5 0.1 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 Rossmann-like domain DUF1965 PF09248.5 KEZ45781.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) 3HCDH_N PF02737.13 KEZ45781.1 - 0.096 12.3 0.2 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KEZ45781.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cupin_2 PF07883.6 KEZ45782.1 - 9.6e-12 44.2 0.1 8.1e-08 31.6 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KEZ45782.1 - 0.01 15.2 0.0 3.3 7.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_4 PF08007.7 KEZ45782.1 - 0.053 12.7 0.2 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Abhydrolase_3 PF07859.8 KEZ45783.1 - 1.7e-14 53.9 0.0 2.8e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ45783.1 - 2e-10 40.2 0.0 1.4e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KEZ45783.1 - 7.5e-10 39.0 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ45783.1 - 3.5e-09 36.5 0.0 6.1e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KEZ45783.1 - 1.4e-05 24.6 0.1 0.00013 21.4 0.1 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KEZ45783.1 - 2.9e-05 23.6 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.23 KEZ45783.1 - 0.00041 19.1 0.0 0.0035 16.1 0.0 2.4 3 0 0 3 3 3 1 Carboxylesterase family Peptidase_S15 PF02129.13 KEZ45783.1 - 0.0085 15.5 0.0 0.11 11.9 0.0 2.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 KEZ45783.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.15 KEZ45783.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 KEZ45783.1 - 0.07 12.3 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.9 KEZ45783.1 - 0.18 10.9 0.0 0.79 8.8 0.0 1.9 2 1 0 2 2 2 0 Secretory lipase Ldh_1_N PF00056.18 KEZ45784.1 - 1e-43 148.5 0.0 1.5e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEZ45784.1 - 8.3e-41 139.5 0.0 1.2e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KEZ45784.1 - 6.5e-06 25.0 0.0 8.8e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KEZ45784.1 - 0.011 16.0 0.2 0.044 14.0 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KEZ45784.1 - 0.087 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Hydrolase PF00702.21 KEZ45785.1 - 4e-22 79.6 0.0 2.2e-21 77.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ45785.1 - 1.3e-21 77.6 0.4 2.8e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KEZ45785.1 - 1.3e-21 76.6 0.0 2.9e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KEZ45785.1 - 0.0005 19.9 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEZ45785.1 - 0.007 15.9 0.1 0.072 12.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KEZ45785.1 - 0.2 10.9 0.7 8.5 5.5 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DUF3636 PF12331.3 KEZ45787.1 - 3.9e-23 81.6 0.2 1.2e-22 80.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) CTP_transf_1 PF01148.15 KEZ45788.1 - 2.1e-78 263.5 31.5 2.6e-78 263.2 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family adh_short PF00106.20 KEZ45789.1 - 2.6e-15 56.7 0.0 8.9e-15 55.0 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ45789.1 - 2.6e-06 27.1 0.0 4.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KEZ45789.1 - 0.0068 16.2 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 5_nucleotid_C PF02872.13 KEZ45790.1 - 5.7e-32 110.8 0.0 1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KEZ45790.1 - 7.8e-09 35.2 0.1 1.2e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEZ45790.1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Esterase_phd PF10503.4 KEZ45791.1 - 9e-22 77.4 0.2 1.3e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KEZ45791.1 - 3.6e-11 42.6 0.4 5.5e-11 42.0 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ45791.1 - 8.5e-08 32.0 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ45791.1 - 8e-07 29.1 0.0 1.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KEZ45791.1 - 0.0012 17.6 0.1 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ45791.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KEZ45791.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KEZ45791.1 - 0.073 12.4 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 KEZ45791.1 - 0.12 11.8 0.0 0.83 9.0 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LSM PF01423.17 KEZ45793.1 - 7.8e-14 50.9 0.3 1.1e-13 50.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain HNH_2 PF13391.1 KEZ45794.1 - 0.0001 22.0 0.1 0.00028 20.6 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease HMGL-like PF00682.14 KEZ45795.1 - 2.8e-61 207.2 0.0 4.3e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KEZ45795.1 - 1e-22 80.3 0.0 4.4e-22 78.2 0.0 2.0 2 1 0 2 2 2 1 LeuA allosteric (dimerisation) domain Ank_2 PF12796.2 KEZ45796.1 - 9.5e-70 230.9 2.5 2.8e-19 69.2 0.0 8.5 6 2 2 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45796.1 - 1.1e-55 182.7 11.5 3.5e-06 26.5 0.0 14.8 14 1 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.1 KEZ45796.1 - 1.1e-44 145.9 5.6 0.00029 20.7 0.0 15.2 16 0 0 16 16 16 8 Ankyrin repeat Ank_4 PF13637.1 KEZ45796.1 - 1.8e-43 146.1 8.0 9.3e-08 32.3 0.0 11.4 9 2 4 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ45796.1 - 3e-29 100.3 10.2 0.0078 16.4 0.0 11.8 7 4 6 13 13 13 9 Ankyrin repeats (many copies) DUF249 PF03158.8 KEZ45796.1 - 0.18 11.3 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 Multigene family 530 protein MFS_1 PF07690.11 KEZ45797.1 - 2.2e-34 118.7 59.4 2.6e-29 102.0 31.3 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 KEZ45797.1 - 9.7e-05 21.0 0.1 9.7e-05 21.0 0.1 3.0 3 1 0 3 3 3 1 LacY proton/sugar symporter DUF1673 PF07895.6 KEZ45797.1 - 1.6 8.2 5.3 3.2 7.2 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Sugar_tr PF00083.19 KEZ45798.1 - 5.1e-76 256.0 24.9 6.1e-76 255.8 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45798.1 - 8.9e-19 67.4 24.9 8.9e-19 67.4 17.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 KEZ45799.1 - 1.3e-11 44.1 23.7 4.2e-06 26.5 5.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ45799.1 - 1.5e-11 43.6 0.0 2.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.18 KEZ45800.1 - 9e-47 159.7 0.5 1.3e-46 159.2 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KEZ45800.1 - 0.013 14.7 0.6 0.038 13.3 0.4 1.8 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase ATP-synt_S1 PF05827.7 KEZ45800.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF2330 PF10092.4 KEZ45800.1 - 0.14 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Ytp1 PF10355.4 KEZ45801.1 - 5.8e-93 311.0 8.7 8.2e-93 310.5 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KEZ45801.1 - 4e-10 39.2 0.2 4e-10 39.2 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) TMEM107 PF14995.1 KEZ45801.1 - 0.01 15.9 5.3 0.79 9.8 0.2 3.3 3 0 0 3 3 3 0 Transmembrane protein NADH-u_ox-rdase PF10785.4 KEZ45801.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Zn_clus PF00172.13 KEZ45802.1 - 0.0059 16.4 14.5 0.012 15.5 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 KEZ45803.1 - 6.2e-20 71.3 0.0 1.3e-12 47.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEZ45803.1 - 4.1e-15 55.4 0.5 6.2e-05 23.0 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45803.1 - 3.7e-12 45.3 0.0 0.21 11.4 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KEZ45803.1 - 5.2e-12 45.9 0.8 0.0012 19.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ45803.1 - 1.1e-11 43.7 0.0 0.018 15.2 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat KAP_NTPase PF07693.9 KEZ45803.1 - 7.2e-05 21.9 0.0 0.00015 20.8 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 KEZ45803.1 - 0.00028 21.0 0.0 0.0021 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KEZ45803.1 - 0.003 17.2 0.0 0.0079 15.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Methyltransf_2 PF00891.13 KEZ45804.1 - 4.6e-23 81.6 0.0 6.8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KEZ45804.1 - 9e-05 22.2 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MarR PF01047.17 KEZ45804.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.2 KEZ45804.1 - 0.033 14.0 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.7 KEZ45804.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.2 KEZ45804.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 MarR family Methyltransf_23 PF13489.1 KEZ45805.1 - 1.8e-24 86.3 0.1 4.1e-24 85.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45805.1 - 1.5e-13 51.2 0.1 1.7e-12 47.9 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45805.1 - 3.8e-13 49.3 0.1 3.9e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45805.1 - 1.1e-12 48.2 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45805.1 - 6.9e-11 42.4 0.0 4.3e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ45805.1 - 3e-07 30.7 0.0 6.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ45805.1 - 3.6e-05 23.7 0.0 0.00034 20.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ45805.1 - 0.00013 21.3 0.0 0.00032 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KEZ45805.1 - 0.0002 20.4 0.0 0.00044 19.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KEZ45805.1 - 0.00021 20.5 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KEZ45805.1 - 0.00044 19.4 0.0 0.001 18.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 KEZ45805.1 - 0.00062 19.8 0.2 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KEZ45805.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 KEZ45805.1 - 0.03 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ubie_methyltran PF01209.13 KEZ45805.1 - 0.082 12.0 0.0 0.41 9.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family NACHT PF05729.7 KEZ45806.1 - 4.6e-05 23.1 0.0 0.00022 20.8 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KEZ45806.1 - 0.00054 20.0 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ45806.1 - 0.0021 18.0 0.0 0.0067 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TMF_DNA_bd PF12329.3 KEZ45806.1 - 0.016 14.9 0.1 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AAA_17 PF13207.1 KEZ45806.1 - 0.053 14.3 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKG6 PF08693.5 KEZ45806.1 - 0.062 12.6 0.8 0.17 11.2 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AAA_10 PF12846.2 KEZ45806.1 - 0.23 10.8 0.0 0.53 9.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain IncA PF04156.9 KEZ45806.1 - 2.5 7.6 4.1 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 IncA protein Aa_trans PF01490.13 KEZ45809.1 - 7.7e-45 153.0 35.1 8.8e-45 152.8 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GFO_IDH_MocA PF01408.17 KEZ45810.1 - 9.3e-17 61.6 0.0 2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 KEZ45810.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA_C PF02894.12 KEZ45810.1 - 0.033 13.9 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain HET PF06985.6 KEZ45811.1 - 1.8e-30 105.8 0.2 3e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KEZ45812.1 - 2.2e-12 46.7 0.0 3.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain VWA_2 PF13519.1 KEZ45812.1 - 0.0038 17.3 0.0 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain SPOR PF05036.8 KEZ45812.1 - 0.043 13.9 0.0 0.56 10.3 0.0 2.4 2 0 0 2 2 2 0 Sporulation related domain PP2C PF00481.16 KEZ45812.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C Pox_ser-thr_kin PF05445.6 KEZ45812.1 - 0.7 8.6 0.0 1.1 7.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2316 PF10078.4 KEZ45813.1 - 0.0052 16.7 0.1 0.24 11.4 0.0 2.2 1 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2316) YjgP_YjgQ PF03739.9 KEZ45814.1 - 0.019 13.6 0.1 0.024 13.4 0.1 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family MFS_1 PF07690.11 KEZ45815.1 - 4.7e-33 114.3 23.6 6.5e-33 113.8 16.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEZ45815.1 - 4.5e-05 22.9 3.0 0.00011 21.7 2.0 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Neurensin PF14927.1 KEZ45815.1 - 0.16 11.3 0.6 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Neurensin NACHT PF05729.7 KEZ45816.1 - 0.00012 21.7 0.1 0.0015 18.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KEZ45816.1 - 0.00053 20.1 0.2 0.0071 16.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KEZ45816.1 - 0.0073 15.7 0.6 0.2 11.0 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 KEZ45816.1 - 0.014 15.4 0.7 0.066 13.1 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 KEZ45816.1 - 0.018 13.9 0.0 0.096 11.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 KEZ45816.1 - 0.028 14.7 1.8 0.38 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KEZ45816.1 - 0.028 13.9 0.2 0.1 12.1 0.0 2.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 KEZ45816.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KEZ45816.1 - 0.057 12.9 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KEZ45816.1 - 0.099 13.4 3.0 0.14 13.0 0.0 2.9 3 1 0 3 3 2 0 AAA domain Lge1 PF11488.3 KEZ45816.1 - 0.1 12.8 0.3 0.4 10.9 0.2 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 ATP_bind_1 PF03029.12 KEZ45816.1 - 0.13 11.8 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Gene66 PF02053.10 KEZ45816.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Gene 66 (IR5) protein Vpu PF00558.14 KEZ45816.1 - 0.18 11.4 1.6 0.58 9.7 1.1 1.8 1 0 0 1 1 1 0 Vpu protein DUF4246 PF14033.1 KEZ45817.1 - 9.7e-99 331.2 0.0 8.7e-80 268.7 0.0 2.2 2 1 0 2 2 2 2 Protein of unknown function (DUF4246) Fungal_trans PF04082.13 KEZ45818.1 - 3.9e-16 58.7 0.1 9.6e-16 57.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45818.1 - 1.1e-13 50.7 27.4 2.3e-08 33.8 4.8 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KEZ45819.1 - 3.1e-70 236.9 17.9 4.8e-69 233.0 8.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter HET PF06985.6 KEZ45821.1 - 5.4e-21 75.2 0.2 1.3e-20 73.9 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.13 KEZ45823.1 - 0.41 10.5 2.4 0.32 10.9 0.4 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KEZ45824.1 - 1.2e-34 119.6 28.9 1.7e-34 119.0 20.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ammonium_transp PF00909.16 KEZ45825.1 - 4.3e-99 331.6 15.8 5.3e-99 331.3 11.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SepZ PF06066.6 KEZ45825.1 - 0.16 12.0 1.0 0.49 10.4 0.7 1.8 1 0 0 1 1 1 0 SepZ Ank_2 PF12796.2 KEZ45826.1 - 1.2e-58 195.4 3.0 1.6e-12 47.5 0.0 8.8 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KEZ45826.1 - 6.7e-46 153.2 22.5 2.9e-05 24.1 1.0 12.0 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ45826.1 - 1.9e-45 152.4 10.5 2.1e-07 31.2 0.0 10.0 5 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.25 KEZ45826.1 - 1.5e-44 147.6 16.2 2.8e-05 23.6 0.9 14.3 14 1 0 14 14 14 9 Ankyrin repeat Ank_3 PF13606.1 KEZ45826.1 - 3.4e-35 116.5 7.1 0.0094 16.1 0.0 14.5 15 1 0 15 15 15 8 Ankyrin repeat SBP_bac_11 PF13531.1 KEZ45826.1 - 0.035 13.7 0.1 0.098 12.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Transferase PF02458.10 KEZ45829.1 - 1.3e-26 93.0 0.0 3.9e-26 91.4 0.0 1.6 1 1 0 1 1 1 1 Transferase family TMF_DNA_bd PF12329.3 KEZ45831.1 - 0.0072 16.1 2.6 0.0086 15.8 0.2 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Prominin PF05478.6 KEZ45831.1 - 0.11 10.0 1.0 0.15 9.5 0.7 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 KEZ45831.1 - 0.11 12.3 1.1 0.24 11.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.1 KEZ45831.1 - 0.33 10.0 5.6 0.53 9.4 3.9 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Glyco_hydro_1 PF00232.13 KEZ45832.1 - 1.1e-134 449.0 0.0 1.7e-134 448.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HET PF06985.6 KEZ45832.1 - 5e-51 172.5 0.4 1.9e-26 92.8 0.0 3.3 3 0 0 3 3 3 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_cc PF11790.3 KEZ45832.1 - 0.025 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Sugar_tr PF00083.19 KEZ45833.1 - 1e-73 248.4 25.0 1.3e-73 248.1 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45833.1 - 1.7e-20 73.0 44.8 6.3e-18 64.6 11.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KEZ45834.1 - 1.8e-14 53.2 0.8 4.3e-14 52.0 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45834.1 - 0.00036 20.3 12.7 0.00071 19.4 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3237 PF11578.3 KEZ45836.1 - 2.3e-20 72.4 0.1 2.6e-20 72.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Acyl-CoA_dh_2 PF08028.6 KEZ45838.1 - 1.5e-17 64.1 0.1 2.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 KEZ45838.1 - 0.00015 21.9 0.0 0.00039 20.5 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KEZ45838.1 - 0.00015 22.3 0.0 0.00029 21.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Olfactory_mark PF06554.7 KEZ45838.1 - 0.15 11.5 0.1 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Olfactory marker protein ADH_zinc_N PF00107.21 KEZ45839.1 - 3.2e-08 33.1 0.3 6.3e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ45839.1 - 2.2e-05 24.1 0.0 5.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KEZ45841.1 - 3.9e-60 203.6 0.0 5.4e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KEZ45842.1 - 5.1e-09 35.6 0.0 0.00073 18.7 0.0 2.5 2 2 0 2 2 2 2 Protein kinase domain APH PF01636.18 KEZ45843.1 - 2.6e-21 76.4 0.0 3.5e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KEZ45843.1 - 7.2e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KEZ45843.1 - 2.6e-05 23.6 0.0 0.058 12.7 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.9 KEZ45843.1 - 0.0014 17.7 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3352 PF11832.3 KEZ45843.1 - 0.093 11.0 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) Cep57_MT_bd PF06657.8 KEZ45843.1 - 0.13 12.1 0.1 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Defensin_2 PF01097.13 KEZ45844.1 - 2e-08 33.8 9.5 2.9e-08 33.2 6.6 1.3 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.15 KEZ45844.1 - 0.048 13.6 6.1 0.068 13.1 4.2 1.2 1 0 0 1 1 1 0 Gamma-thionin family FAP PF07174.6 KEZ45844.1 - 0.087 12.1 1.4 0.098 11.9 1.0 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Toxin_38 PF14866.1 KEZ45844.1 - 0.22 11.6 11.8 0.37 10.9 8.2 1.4 1 1 0 1 1 1 0 Potassium channel toxin DUF4066 PF13278.1 KEZ45845.1 - 2e-15 56.4 0.0 2.4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KEZ45845.1 - 5.4e-08 32.4 0.0 7.7e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3275 PF11679.3 KEZ45847.1 - 0.0053 16.4 0.2 0.011 15.3 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3275) Mitofilin PF09731.4 KEZ45848.1 - 1.3e-12 47.2 0.0 1.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4254 PF14063.1 KEZ45849.1 - 0.011 15.3 0.2 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Dus PF01207.12 KEZ45849.1 - 0.1 11.3 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Glycogen_syn PF05693.8 KEZ45850.1 - 3.7e-207 689.5 0.0 4.4e-207 689.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KEZ45850.1 - 1.6e-07 30.8 0.0 9.2e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEZ45850.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 KEZ45850.1 - 0.0012 18.4 0.1 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Hemerythrin PF01814.18 KEZ45851.1 - 1.4e-13 51.1 2.1 2e-13 50.6 1.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Elongin_A PF06881.6 KEZ45851.1 - 0.036 14.4 1.1 0.073 13.4 0.8 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Gp-FAR-1 PF05823.7 KEZ45851.1 - 0.15 12.0 1.2 0.76 9.7 0.9 2.0 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) adh_short PF00106.20 KEZ45852.1 - 2.4e-23 82.8 0.3 3.7e-22 79.0 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ45852.1 - 6.3e-20 71.9 0.1 4.9e-19 69.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ45852.1 - 4.2e-06 26.5 0.1 1.1e-05 25.1 0.0 1.7 1 1 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KEZ45852.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KEZ45852.1 - 0.0066 16.4 0.1 0.53 10.2 0.1 2.5 2 1 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 KEZ45852.1 - 0.043 13.4 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KEZ45852.1 - 0.069 12.0 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CHZ PF09649.5 KEZ45853.1 - 0.035 13.3 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ Amino_oxidase PF01593.19 KEZ45854.1 - 2.3e-48 165.3 0.1 3.7e-48 164.7 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KEZ45854.1 - 5.8e-13 48.6 0.2 1.4e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ45854.1 - 4.1e-09 35.8 0.7 1.5e-07 30.6 0.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ45854.1 - 8.3e-06 24.9 0.3 1.5e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ45854.1 - 8.9e-05 21.1 0.0 0.00014 20.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KEZ45854.1 - 0.00016 20.8 0.1 0.00028 20.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ45854.1 - 0.00027 20.8 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ45854.1 - 0.00052 19.1 0.0 0.00099 18.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ45854.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KEZ45854.1 - 0.0015 17.6 0.4 0.0068 15.4 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KEZ45854.1 - 0.0032 17.5 0.1 0.0076 16.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KEZ45854.1 - 0.0034 16.2 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KEZ45854.1 - 0.011 14.6 0.2 0.018 14.0 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4082 PF13313.1 KEZ45854.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Fungal_trans PF04082.13 KEZ45855.1 - 2e-14 53.1 0.0 3.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45855.1 - 7.9e-08 32.0 8.0 1.6e-07 31.0 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KEZ45856.1 - 1.8e-37 128.9 0.0 1.8e-33 115.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3936 PF13072.1 KEZ45856.1 - 0.017 14.5 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) HgmA PF04209.8 KEZ45857.1 - 3.9e-156 519.7 0.1 4.6e-103 344.8 0.1 2.3 1 1 1 2 2 2 2 homogentisate 1,2-dioxygenase Beta-lactamase PF00144.19 KEZ45858.1 - 3.9e-45 154.3 0.4 5.1e-45 153.9 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase zf-H2C2_2 PF13465.1 KEZ45859.1 - 0.28 11.5 0.5 0.28 11.5 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger double domain MFS_1 PF07690.11 KEZ45860.1 - 7.7e-31 107.0 47.4 7.7e-31 107.0 32.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ45860.1 - 1.3e-13 50.0 11.9 1.9e-13 49.5 8.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4440 PF14534.1 KEZ45861.1 - 0.016 15.3 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Phage_T4_Gp30_7 PF06919.6 KEZ45861.1 - 0.03 14.3 0.0 0.08 12.9 0.0 1.7 2 0 0 2 2 2 0 Phage Gp30.7 protein adh_short PF00106.20 KEZ45862.1 - 1.7e-13 50.8 0.1 9e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ45862.1 - 8.2e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ45862.1 - 0.00012 21.5 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEZ45862.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 KEZ45862.1 - 0.045 13.5 0.0 0.34 10.7 0.0 2.2 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_11 PF00457.12 KEZ45863.1 - 4.1e-62 208.7 11.9 4.8e-62 208.5 8.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Fungal_trans PF04082.13 KEZ45864.1 - 1.1e-16 60.5 0.2 1.6e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KEZ45864.1 - 4.3e-06 26.7 15.1 0.0051 17.0 3.6 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ45864.1 - 8.1e-05 22.6 5.9 8.1e-05 22.6 4.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 KEZ45864.1 - 0.00025 20.8 11.7 0.00025 20.8 8.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 KEZ45864.1 - 0.0086 16.2 1.8 0.037 14.2 1.3 2.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KEZ45864.1 - 0.14 12.3 6.0 0.13 12.4 1.3 2.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KEZ45864.1 - 0.14 12.4 12.0 1.6 9.1 0.3 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KEZ45864.1 - 0.31 10.9 6.4 0.76 9.7 0.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger ADH_N PF08240.7 KEZ45865.1 - 2.1e-23 82.1 0.1 4.2e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ45865.1 - 1.1e-19 70.3 0.1 2.1e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KEZ45865.1 - 0.056 12.5 2.0 5.2 6.1 0.0 2.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 KEZ45865.1 - 0.075 13.6 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KEZ45866.1 - 2.7e-70 237.1 0.0 3.2e-69 233.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 KEZ45867.1 - 2e-23 83.3 0.0 3.4e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ45867.1 - 1.5e-09 38.1 0.0 2.8e-08 34.0 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ45867.1 - 0.0098 15.9 0.0 0.19 11.7 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.19 KEZ45868.1 - 4.8e-08 32.9 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KEZ45868.1 - 1.5e-06 28.3 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEZ45868.1 - 0.0002 21.4 0.1 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KEZ45868.1 - 0.0015 18.3 0.0 0.0084 15.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEZ45868.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein MFS_1 PF07690.11 KEZ45869.1 - 1.9e-30 105.7 31.1 1.9e-30 105.7 21.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 KEZ45869.1 - 0.0018 17.4 0.8 0.0018 17.4 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1616) Epimerase PF01370.16 KEZ45870.1 - 6.9e-13 48.5 0.0 9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KEZ45870.1 - 1.9e-10 39.8 0.0 3.1e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KEZ45870.1 - 1.1e-08 35.3 0.1 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KEZ45870.1 - 4.4e-07 29.0 0.0 9e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 KEZ45870.1 - 1.7e-05 24.1 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KEZ45870.1 - 0.052 13.4 0.6 0.47 10.3 0.4 2.3 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 KEZ45871.1 - 1.2e-54 185.0 0.0 1.5e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ45871.1 - 1.6e-13 51.0 0.0 2.1e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ45871.1 - 6.5e-07 28.3 0.0 8.7e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KEZ45871.1 - 9.1e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KEZ45871.1 - 0.0015 17.5 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KEZ45871.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KEZ45871.1 - 0.036 14.3 0.1 0.083 13.2 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_61 PF03443.9 KEZ45872.1 - 5e-66 222.6 0.0 7.4e-66 222.0 0.0 1.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 KEZ45873.1 - 3.4e-54 183.9 0.0 4.6e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_4 PF08386.5 KEZ45874.1 - 5e-20 71.3 0.0 9.3e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEZ45874.1 - 1.1e-11 44.7 0.0 2.4e-09 37.1 0.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ45874.1 - 2.4e-09 37.4 0.0 1.4e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transferase PF02458.10 KEZ45875.1 - 7.3e-11 41.1 0.0 8.1e-10 37.7 0.0 2.1 1 1 0 1 1 1 1 Transferase family Glyco_hydro_16 PF00722.16 KEZ45876.1 - 1.9e-22 79.4 0.8 1.2e-21 76.7 0.3 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 KEZ45877.1 - 7.7e-47 159.4 3.3 7.7e-47 159.4 2.3 3.2 3 1 1 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KEZ45877.1 - 8.6e-08 32.2 0.1 4.2e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEZ45877.1 - 0.00075 18.8 0.1 0.0023 17.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEZ45877.1 - 0.0089 15.7 0.0 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 RTA1 PF04479.8 KEZ45878.1 - 2.4e-44 151.5 2.9 3.2e-44 151.0 2.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF1180 PF06679.7 KEZ45878.1 - 0.23 11.3 0.5 12 5.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) zf-DHHC PF01529.15 KEZ45878.1 - 0.5 9.7 2.4 1.9 7.8 1.2 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase NfeD PF01957.13 KEZ45878.1 - 0.78 9.8 7.9 0.31 11.1 0.6 2.9 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF454 PF04304.8 KEZ45878.1 - 0.85 9.6 0.1 0.85 9.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF454) Glyco_hydro_43 PF04616.9 KEZ45879.1 - 1e-19 70.7 0.8 1.3e-19 70.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cu_bind_like PF02298.12 KEZ45880.1 - 0.12 12.2 0.2 0.6 9.9 0.2 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Methyltransf_23 PF13489.1 KEZ45881.1 - 3.4e-17 62.6 0.0 4.9e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ45881.1 - 1e-11 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ45881.1 - 9.2e-10 38.8 0.0 7.1e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ45881.1 - 3.5e-08 34.0 0.0 4.3e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ45881.1 - 6.8e-07 28.9 0.0 0.0039 16.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ45881.1 - 3.4e-05 23.0 0.0 0.046 12.8 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KEZ45881.1 - 0.0011 19.3 0.0 0.0044 17.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ45881.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KEZ45881.1 - 0.02 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KEZ45881.1 - 0.048 13.1 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KEZ45881.1 - 0.058 12.5 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 KEZ45881.1 - 0.083 12.8 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Peptidase_M3 PF01432.15 KEZ45882.1 - 1e-95 321.4 0.0 1.5e-95 320.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF455 PF04305.9 KEZ45882.1 - 0.05 12.8 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) CorA PF01544.13 KEZ45884.1 - 4.2e-07 29.3 0.0 7.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Tricorn_C1 PF14684.1 KEZ45884.1 - 0.29 11.0 3.8 0.39 10.6 0.3 2.9 3 0 0 3 3 3 0 Tricorn protease C1 domain KIF1B PF12423.3 KEZ45884.1 - 4.3 7.4 5.1 7.4 6.6 0.2 2.6 2 0 0 2 2 2 0 Kinesin protein 1B DUF4191 PF13829.1 KEZ45885.1 - 3 6.8 5.2 0.45 9.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF1700 PF08006.6 KEZ45885.1 - 3.8 6.7 13.6 5.4 6.2 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) MFS_1 PF07690.11 KEZ45886.1 - 2.8e-21 75.6 56.3 1.8e-16 59.7 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1290 PF06947.7 KEZ45886.1 - 0.063 13.1 4.3 1.7 8.6 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1290) Kinesin PF00225.18 KEZ45887.1 - 1.1e-114 382.6 0.0 1.7e-114 382.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_23 PF13476.1 KEZ45887.1 - 0.14 12.4 5.0 0.04 14.2 0.6 2.1 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 KEZ45887.1 - 0.16 9.2 15.3 0.22 8.8 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zn_clus PF00172.13 KEZ45888.1 - 1.3e-07 31.3 7.1 2e-07 30.8 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NACHT PF05729.7 KEZ45889.1 - 5.9e-07 29.2 0.3 1.5e-05 24.7 0.2 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ45889.1 - 4.9e-05 23.4 0.1 0.00038 20.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KEZ45889.1 - 0.0062 16.6 0.0 0.052 13.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KEZ45889.1 - 0.01 16.1 0.1 0.1 12.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 KEZ45889.1 - 0.04 14.7 0.0 0.25 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KEZ45889.1 - 0.096 12.9 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain CGI-121 PF08617.5 KEZ45890.1 - 1e-48 165.0 0.0 1.1e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Eaf7 PF07904.8 KEZ45890.1 - 0.035 14.0 0.1 2.4 8.2 0.0 2.3 1 1 1 2 2 2 0 Chromatin modification-related protein EAF7 Pro_dh PF01619.13 KEZ45891.1 - 2.4e-37 128.6 0.0 3.2e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase NIF PF03031.13 KEZ45892.1 - 3.8e-36 124.1 0.0 5.6e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2077 PF09850.4 KEZ45892.1 - 0.22 10.8 0.7 19 4.6 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF106 PF01956.11 KEZ45892.1 - 1.4 8.4 4.6 3.1 7.3 3.2 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 RNase_PH PF01138.16 KEZ45893.1 - 1.8e-36 125.4 0.6 5e-36 123.9 0.1 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.15 KEZ45894.1 - 5.8e-33 112.6 0.2 1.9e-27 94.9 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KEZ45894.1 - 1.9e-08 34.4 0.6 1.3e-05 25.3 0.4 2.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 KEZ45894.1 - 2.1e-08 34.2 0.0 6.2e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KEZ45894.1 - 9.7e-07 28.8 0.0 0.0027 17.7 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.16 KEZ45894.1 - 0.003 17.2 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 KEZ45894.1 - 0.014 15.4 0.1 0.059 13.3 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.1 KEZ45894.1 - 0.072 12.9 0.4 0.7 9.7 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin domain ERp29_N PF07912.8 KEZ45894.1 - 0.098 12.5 0.0 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 ERp29, N-terminal domain HTH_6 PF01418.12 KEZ45894.1 - 0.1 12.3 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DUF605 PF04652.11 KEZ45895.1 - 3.6e-70 237.2 17.6 4.5e-70 236.9 12.2 1.1 1 0 0 1 1 1 1 Vta1 like DUF1996 PF09362.5 KEZ45896.1 - 2.2e-89 299.1 0.1 2.7e-89 298.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Bax1-I PF01027.15 KEZ45897.1 - 7.1e-33 113.9 8.7 9.9e-33 113.4 6.0 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.16 KEZ45898.1 - 2e-57 193.4 0.0 2.4e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase LEA_6 PF10714.4 KEZ45898.1 - 0.11 12.3 0.1 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Sugar_tr PF00083.19 KEZ45899.1 - 6.9e-80 268.8 16.1 8e-80 268.6 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ45899.1 - 8.5e-30 103.6 23.0 8.5e-30 103.6 16.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KEZ45899.1 - 3e-05 22.4 0.9 3e-05 22.4 0.6 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) AA_permease_C PF13906.1 KEZ45899.1 - 0.045 13.6 1.3 0.15 11.9 0.9 1.9 1 0 0 1 1 1 0 C-terminus of AA_permease MIP PF00230.15 KEZ45900.1 - 4.1e-49 167.0 20.6 5.2e-49 166.7 14.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3328 PF11807.3 KEZ45901.1 - 1.7e-50 171.6 1.4 2.2e-50 171.3 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.13 KEZ45902.1 - 3.3e-18 65.4 0.0 6.2e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ45902.1 - 2e-09 37.1 12.4 3.4e-09 36.4 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 KEZ45903.1 - 3.3e-14 52.6 0.0 3.7e-13 49.2 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain Ribosomal_S21e PF01249.13 KEZ45904.1 - 1.1e-40 137.4 0.1 1.2e-40 137.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Fork_head PF00250.13 KEZ45905.1 - 3.3e-12 46.2 0.5 1.4e-11 44.2 0.3 1.9 1 1 0 1 1 1 1 Fork head domain CactinC_cactus PF09732.4 KEZ45906.1 - 1.4e-55 186.1 4.6 2.5e-55 185.4 3.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 KEZ45906.1 - 1e-54 184.6 10.1 1.4e-54 184.2 7.0 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin dNK PF01712.14 KEZ45906.1 - 0.017 15.0 0.5 0.046 13.6 0.2 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF1087 PF06465.8 KEZ45906.1 - 1.8 8.5 6.4 0.3 11.0 0.2 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) Glyco_hydro_3 PF00933.16 KEZ45907.1 - 4e-55 186.9 0.0 6.1e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KEZ45907.1 - 1e-44 152.7 0.7 2e-44 151.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KEZ45907.1 - 5.9e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain gag-asp_proteas PF13975.1 KEZ45908.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Mannosyl_trans3 PF11051.3 KEZ45909.1 - 3.1e-42 144.8 0.0 3.2e-40 138.2 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Syja_N PF02383.13 KEZ45910.1 - 2.8e-86 289.1 0.0 3.5e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 KEZ45911.1 - 2.7e-58 195.9 0.1 3.2e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ45911.1 - 5.7e-19 68.7 0.0 9.1e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ45911.1 - 1.4e-14 53.7 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ45911.1 - 8.4e-08 31.6 0.0 9.9e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KEZ45911.1 - 4.2e-07 29.5 0.0 6.1e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KEZ45911.1 - 1.7e-05 24.7 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ45911.1 - 0.038 13.1 0.1 0.14 11.3 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ45911.1 - 0.14 12.1 0.5 0.48 10.3 0.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KEZ45911.1 - 0.15 12.1 0.1 3 7.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain Mitofilin PF09731.4 KEZ45912.1 - 4.6e-143 477.9 19.6 5.8e-143 477.6 13.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein WXG100 PF06013.7 KEZ45912.1 - 0.0086 16.0 4.3 0.086 12.8 0.5 3.2 1 1 1 2 2 2 1 Proteins of 100 residues with WXG Pex14_N PF04695.8 KEZ45912.1 - 0.046 13.7 1.2 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1848 PF08902.6 KEZ45912.1 - 0.063 12.8 2.1 1.8 7.9 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) AAA_13 PF13166.1 KEZ45912.1 - 0.29 9.5 10.0 0.53 8.6 6.9 1.5 1 0 0 1 1 1 0 AAA domain MGC-24 PF05283.6 KEZ45912.1 - 4 7.1 6.8 7.3 6.3 4.7 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF3373 PF11853.3 KEZ45912.1 - 7.9 4.8 7.0 11 4.3 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Mur_ligase_M PF08245.7 KEZ45913.1 - 1.3e-07 31.8 0.2 0.00013 22.1 0.0 2.6 2 1 0 2 2 2 2 Mur ligase middle domain adh_short PF00106.20 KEZ45914.1 - 4.6e-21 75.4 0.4 6.5e-21 74.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ45914.1 - 1.3e-09 37.9 0.2 2.6e-09 36.9 0.1 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KEZ45914.1 - 0.0002 20.1 0.1 0.0016 17.2 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ45914.1 - 0.015 14.6 0.0 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KEZ45914.1 - 0.028 14.4 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_23 PF13489.1 KEZ45914.1 - 0.085 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain gag-asp_proteas PF13975.1 KEZ45915.1 - 1.7e-12 46.9 0.2 2.3e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KEZ45915.1 - 4.1e-08 33.5 0.0 0.00015 22.1 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease Asp_protease PF09668.5 KEZ45915.1 - 0.00017 21.1 0.2 0.12 11.9 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease zf-C2H2_4 PF13894.1 KEZ45915.1 - 0.0049 17.1 12.5 2.4 8.6 0.3 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ45915.1 - 0.013 15.7 4.1 1.4 9.3 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ45915.1 - 5.3 7.6 16.1 0.42 11.0 0.2 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3623 PF12291.3 KEZ45916.1 - 0.012 14.6 2.1 0.017 14.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) DUF3429 PF11911.3 KEZ45916.1 - 0.13 12.2 4.0 0.068 13.1 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3429) Ras PF00071.17 KEZ45917.1 - 1.6e-42 144.6 0.0 4.1e-42 143.3 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KEZ45917.1 - 4.2e-15 56.2 0.0 6.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ45917.1 - 6.9e-11 41.7 0.0 2e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ45917.1 - 5.2e-05 22.5 0.0 7e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KEZ45917.1 - 0.00076 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 KEZ45917.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KEZ45917.1 - 0.0021 17.5 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KEZ45917.1 - 0.0048 16.3 0.0 0.022 14.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KEZ45917.1 - 0.0086 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KEZ45917.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KEZ45917.1 - 0.028 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KEZ45917.1 - 0.028 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KEZ45917.1 - 0.029 13.8 0.0 0.085 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KEZ45917.1 - 0.035 14.1 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KEZ45917.1 - 0.058 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KEZ45917.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 KEZ45917.1 - 0.21 11.0 0.3 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_2 PF00703.16 KEZ45918.1 - 3.8e-12 46.6 0.9 1.3e-11 44.8 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KEZ45918.1 - 8.6e-12 44.9 0.2 2.5e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KEZ45918.1 - 4e-05 22.6 0.1 7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cadherin-like PF12733.2 KEZ45918.1 - 0.062 13.5 4.5 0.26 11.5 0.8 3.0 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain Ribosomal_L14 PF00238.14 KEZ45919.1 - 4.8e-32 110.2 0.0 5.4e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF2413 PF10310.4 KEZ45921.1 - 1.1e-132 443.0 0.1 1.3e-132 442.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Pex14_N PF04695.8 KEZ45921.1 - 3.5 7.6 8.6 1.6 8.7 3.4 2.2 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_11 PF13414.1 KEZ45922.1 - 7.8e-55 182.4 27.3 4.6e-17 61.4 1.6 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 KEZ45922.1 - 5.6e-41 136.5 20.8 1.7e-05 24.2 0.1 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ45922.1 - 1.7e-35 118.0 22.9 0.00012 21.7 0.2 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ45922.1 - 7.3e-21 74.3 14.0 6e-06 26.7 0.4 6.8 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ45922.1 - 2.3e-20 72.3 9.2 2e-10 40.4 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ45922.1 - 8e-17 60.2 10.6 0.087 13.5 0.0 9.5 6 3 3 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ45922.1 - 8e-13 47.5 15.0 0.02 15.0 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ45922.1 - 8.3e-13 47.9 3.7 0.00088 19.0 0.0 6.4 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ45922.1 - 4e-12 45.0 13.9 0.0088 15.7 0.0 7.7 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ45922.1 - 4e-12 44.9 8.5 0.16 11.8 0.1 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ45922.1 - 6.1e-11 42.5 10.5 0.0046 17.2 0.0 6.1 6 1 1 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KEZ45922.1 - 1.2e-05 25.2 10.7 0.00013 21.9 0.4 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEZ45922.1 - 4.4e-05 23.6 13.4 9.2 6.9 0.0 7.7 8 1 0 8 8 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEZ45922.1 - 0.001 18.8 1.5 3.9 7.4 0.0 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.3 KEZ45922.1 - 0.0016 17.2 0.2 0.0016 17.2 0.1 3.6 3 1 0 4 4 4 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.1 KEZ45922.1 - 0.0064 16.3 6.3 0.23 11.4 0.0 4.7 6 0 0 6 6 4 1 Tetratricopeptide repeat Chol_subst-bind PF09129.6 KEZ45922.1 - 0.066 12.3 0.2 0.27 10.3 0.1 1.9 2 0 0 2 2 2 0 Cholesterol oxidase, substrate-binding TPR_20 PF14561.1 KEZ45922.1 - 0.42 10.7 11.0 0.55 10.3 0.2 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat EMP24_GP25L PF01105.19 KEZ45922.1 - 1.3 8.7 3.7 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RNA_pol_Rpc34 PF05158.7 KEZ45924.1 - 1.7e-89 300.2 0.0 2.3e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 KEZ45924.1 - 6.2e-05 23.3 0.1 0.27 11.6 0.0 2.9 3 0 0 3 3 3 2 Replication protein A C terminal B-block_TFIIIC PF04182.7 KEZ45924.1 - 0.019 14.8 0.1 0.061 13.1 0.0 1.8 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Rhodanese PF00581.15 KEZ45925.1 - 4.9e-09 36.5 0.1 8.5e-09 35.7 0.1 1.4 1 1 0 1 1 1 1 Rhodanese-like domain LSM PF01423.17 KEZ45926.1 - 2.2e-18 65.5 0.7 2.6e-18 65.3 0.5 1.0 1 0 0 1 1 1 1 LSM domain NTR2 PF15458.1 KEZ45927.1 - 7.5e-65 218.6 23.4 7.5e-65 218.6 16.2 1.9 2 1 0 2 2 2 1 Nineteen complex-related protein 2 GAS PF13851.1 KEZ45927.1 - 0.47 9.6 8.1 0.13 11.4 0.2 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3844 PF12955.2 KEZ45928.1 - 2.9e-33 114.0 0.8 5.7e-33 113.1 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 KEZ45928.1 - 2.8 8.2 9.1 2.3 8.4 1.4 2.6 2 0 0 2 2 2 0 EGF-like domain Pkinase PF00069.20 KEZ45929.1 - 3.7e-25 88.5 0.0 6.5e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45929.1 - 4.5e-14 52.1 0.0 2.9e-13 49.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase E1-E2_ATPase PF00122.15 KEZ45931.1 - 3.2e-60 203.0 0.7 8.1e-60 201.7 0.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ45931.1 - 1.9e-43 148.1 10.9 1.9e-43 148.1 7.5 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ45931.1 - 1.2e-27 97.7 0.0 5.3e-27 95.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ45931.1 - 1.9e-19 69.4 0.1 4.5e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ45931.1 - 2.3e-13 50.7 0.0 5.1e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ45931.1 - 8.3e-09 34.7 0.2 7.3e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KEZ45931.1 - 0.00024 20.7 0.1 0.00043 19.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 KEZ45931.1 - 0.32 10.9 0.0 0.32 10.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) ADH_N PF08240.7 KEZ45933.1 - 7.2e-31 106.1 1.5 1.5e-30 105.1 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ45933.1 - 1.1e-25 89.6 0.2 1.8e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ45933.1 - 7.9e-05 23.5 0.0 0.0002 22.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KEZ45933.1 - 0.00064 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 KEZ45933.1 - 0.0044 16.6 0.6 0.0082 15.7 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_31 PF13847.1 KEZ45933.1 - 0.006 16.1 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KEZ45933.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEZ45933.1 - 0.06 12.7 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 KEZ45933.1 - 0.079 11.4 0.7 0.11 10.9 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KEZ45933.1 - 0.12 12.7 1.0 0.24 11.8 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Met_10 PF02475.11 KEZ45933.1 - 0.19 11.2 0.3 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 Met-10+ like-protein Atg14 PF10186.4 KEZ45935.1 - 2.2e-17 62.9 0.0 4.5e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KEZ45935.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Filament PF00038.16 KEZ45935.1 - 0.03 13.8 4.0 0.046 13.1 2.8 1.2 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 KEZ45935.1 - 0.87 8.1 5.0 1.3 7.6 3.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.7 KEZ45935.1 - 4.3 7.1 5.7 1.2 8.9 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 KEZ45936.1 - 1.3e-17 62.9 12.5 8.9e-07 28.5 1.3 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 KEZ45936.1 - 3.7e-14 53.2 0.6 1.2e-13 51.6 0.4 2.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KEZ45936.1 - 5.6e-11 42.7 4.1 5.3e-10 39.5 2.9 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase eIF2A PF08662.6 KEZ45936.1 - 0.075 12.7 0.0 0.95 9.1 0.0 2.2 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.20 KEZ45937.1 - 4.2e-63 212.9 0.0 7.1e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45937.1 - 6.7e-35 120.4 0.0 2e-29 102.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEZ45937.1 - 5.8e-06 25.4 0.0 0.0062 15.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KEZ45937.1 - 0.0097 15.6 0.2 0.026 14.2 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KEZ45937.1 - 0.09 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apolipoprotein PF01442.13 KEZ45938.1 - 0.1 12.1 0.1 8.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CorA PF01544.13 KEZ45938.1 - 0.19 10.7 1.8 0.38 9.7 1.2 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 KEZ45939.1 - 3.9e-24 85.2 0.0 1.1e-23 83.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45939.1 - 2.1e-10 40.1 1.5 0.0025 16.9 0.0 3.8 3 1 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 KEZ45939.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Na_Ca_ex PF01699.19 KEZ45940.1 - 1.4e-33 115.4 19.6 2e-17 63.1 0.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Zip PF02535.17 KEZ45940.1 - 0.00033 19.7 0.3 0.00033 19.7 0.2 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter SelP_N PF04592.9 KEZ45940.1 - 0.79 9.0 7.9 1.6 8.0 5.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1180 PF06679.7 KEZ45940.1 - 5 6.9 6.6 0.87 9.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) FAD-oxidase_C PF02913.14 KEZ45941.1 - 8.3e-57 192.3 0.1 1.6e-56 191.3 0.1 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEZ45941.1 - 2e-37 127.7 0.0 5e-37 126.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pkinase PF00069.20 KEZ45942.1 - 1e-72 244.4 0.0 1.7e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ45942.1 - 4.1e-38 130.9 0.0 8.6e-38 129.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ45942.1 - 0.00025 20.1 0.1 0.35 9.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KEZ45942.1 - 0.0016 17.5 0.3 0.0054 15.8 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEZ45942.1 - 0.0083 15.8 0.0 0.17 11.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-C2H2 PF00096.21 KEZ45943.1 - 8.1e-07 29.0 2.5 0.0064 16.7 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KEZ45943.1 - 0.00011 22.2 1.6 0.1 12.8 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KEZ45943.1 - 0.00057 20.0 1.6 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 KEZ45943.1 - 0.057 13.5 0.8 0.12 12.4 0.5 1.6 1 1 0 1 1 1 0 LIM domain zf-Di19 PF05605.7 KEZ45943.1 - 0.16 12.1 2.0 4.1 7.6 0.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_60s PF00428.14 KEZ45943.1 - 7.9 6.9 12.6 7.7 6.9 1.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein LepA_C PF06421.7 KEZ45944.1 - 0.38 10.6 0.0 0.72 9.7 0.0 1.4 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus tRNA-synt_1 PF00133.17 KEZ45945.1 - 1e-151 505.9 0.0 1.4e-151 505.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEZ45945.1 - 2.9e-20 72.2 0.0 4.1e-11 42.1 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEZ45945.1 - 1.1e-15 57.6 0.0 2.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KEZ45945.1 - 0.0034 16.5 0.0 0.84 8.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 KEZ45945.1 - 0.16 11.6 1.1 0.32 10.6 0.8 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF945 PF06097.6 KEZ45945.1 - 0.26 10.0 0.0 0.43 9.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) HET PF06985.6 KEZ45947.1 - 7e-25 87.8 0.2 1.1e-24 87.1 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fasciclin PF02469.17 KEZ45948.1 - 4.8e-21 75.1 0.1 3.1e-18 66.0 0.0 3.1 3 0 0 3 3 3 2 Fasciclin domain Tom37_C PF11801.3 KEZ45949.1 - 5.1e-22 78.5 0.0 7.9e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 KEZ45949.1 - 4.4e-19 68.5 0.2 1.4e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein UPF0183 PF03676.9 KEZ45950.1 - 1.7e-36 125.6 0.0 4.5e-22 78.1 0.0 4.3 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) tRNA-synt_1 PF00133.17 KEZ45951.1 - 1.1e-226 753.5 0.5 6.1e-226 751.0 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KEZ45951.1 - 2.1e-33 115.2 0.0 4.9e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KEZ45951.1 - 1.7e-15 56.6 0.2 0.00013 20.8 0.0 4.8 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KEZ45951.1 - 8.4e-11 41.5 3.8 2.6e-08 33.3 0.0 3.0 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 KEZ45951.1 - 0.0064 15.6 0.0 0.048 12.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Kinesin PF00225.18 KEZ45952.1 - 2.8e-107 358.2 0.2 5.6e-107 357.3 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 KEZ45952.1 - 1.5e-08 34.9 2.2 1.5e-08 34.9 1.5 4.5 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding RRN9 PF10680.4 KEZ45953.1 - 1.1e-18 66.7 0.1 4.3e-18 64.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.21 KEZ45953.1 - 0.013 15.7 0.5 0.058 13.7 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ45953.1 - 0.016 15.4 0.5 0.016 15.4 0.3 2.2 3 0 0 3 3 3 0 C2H2-type zinc finger PIG-U PF06728.8 KEZ45954.1 - 1.2e-118 396.3 29.3 1.3e-118 396.1 20.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U HMG-CoA_red PF00368.13 KEZ45955.1 - 1.4e-154 514.2 5.5 1.8e-154 513.9 3.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KEZ45955.1 - 2.2e-45 154.0 0.3 4.7e-45 152.9 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KEZ45955.1 - 3.6e-12 46.0 5.9 4.3e-11 42.4 4.1 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KEZ45955.1 - 6.3e-07 27.7 1.9 9.8e-07 27.0 1.3 1.2 1 0 0 1 1 1 1 Patched family Isochorismatase PF00857.15 KEZ45956.1 - 1.6e-25 89.9 0.0 6.1e-25 88.1 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family Dabb PF07876.7 KEZ45957.1 - 1.2e-25 89.7 0.0 1.5e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe_hyd_SSU PF02256.12 KEZ45957.1 - 0.13 12.2 0.1 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Iron hydrogenase small subunit Strep_67kDa_ant PF06100.6 KEZ45958.1 - 1.4e-113 379.9 0.0 3.5e-98 329.1 0.0 3.0 2 1 0 2 2 2 2 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 KEZ45958.1 - 8.7e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ45958.1 - 0.0052 15.7 0.0 0.49 9.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ45958.1 - 0.0069 16.1 0.1 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trypan_PARP PF05887.6 KEZ45958.1 - 3 7.6 17.2 0.15 11.8 7.8 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) GWT1 PF06423.7 KEZ45959.1 - 1.3e-44 151.6 3.0 1.3e-44 151.6 2.1 2.4 2 0 0 2 2 2 1 GWT1 Glyco_tranf_2_3 PF13641.1 KEZ45961.1 - 3.5e-15 56.4 0.0 7e-15 55.4 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEZ45961.1 - 7.8e-08 31.8 0.0 1.7e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KEZ45961.1 - 3.8e-05 23.4 0.0 0.0001 22.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF4140 PF13600.1 KEZ45962.1 - 0.33 11.4 7.3 0.77 10.2 4.9 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SPATIAL PF15256.1 KEZ45962.1 - 5.8 6.9 7.2 1.2 9.1 2.5 1.6 2 0 0 2 2 2 0 SPATIAL DUF2897 PF11446.3 KEZ45963.1 - 0.019 14.7 0.1 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Claudin_3 PF06653.6 KEZ45963.1 - 8 6.1 16.5 2.5 7.7 4.7 2.9 1 1 0 2 2 2 0 Tight junction protein, Claudin-like CLTH PF10607.4 KEZ45964.1 - 2.1e-32 111.8 0.2 5e-32 110.5 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KEZ45964.1 - 1.3e-18 66.4 5.4 1.5e-18 66.2 2.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 KEZ45964.1 - 3.1e-06 26.8 2.0 5.4e-06 26.1 1.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KEZ45964.1 - 3.5e-06 26.9 3.2 6.4e-06 26.0 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ45964.1 - 1e-05 25.1 1.8 1.9e-05 24.2 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEZ45964.1 - 3.3e-05 23.4 2.2 6e-05 22.6 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ45964.1 - 3.6e-05 23.3 3.7 7.1e-05 22.3 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KEZ45964.1 - 0.00014 21.1 0.2 0.00014 21.1 0.2 1.6 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 KEZ45964.1 - 0.0007 19.4 1.5 0.0015 18.3 1.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Zn_Tnp_IS1595 PF12760.2 KEZ45964.1 - 0.018 14.8 0.1 0.061 13.1 0.1 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-MIZ PF02891.15 KEZ45964.1 - 0.023 14.1 2.3 0.051 13.0 1.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 KEZ45964.1 - 0.032 13.8 1.8 0.057 13.0 1.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AA_synth PF06684.6 KEZ45964.1 - 0.04 13.2 0.0 0.62 9.3 0.0 2.2 2 0 0 2 2 2 0 Amino acid synthesis Prok-RING_4 PF14447.1 KEZ45964.1 - 0.12 11.9 0.6 0.26 10.8 0.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 KEZ45964.1 - 0.18 11.3 6.1 1.4 8.4 3.2 2.7 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Tim10_DDP PF02953.10 KEZ45965.1 - 8.9e-18 63.3 1.8 1.1e-17 63.0 1.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.4 KEZ45965.1 - 0.15 11.8 1.0 0.67 9.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NUDIX PF00293.23 KEZ45966.1 - 1.3e-09 37.7 1.3 1.7e-09 37.4 0.9 1.1 1 0 0 1 1 1 1 NUDIX domain Pro_isomerase PF00160.16 KEZ45969.1 - 2.4e-41 141.5 0.5 2.7e-41 141.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 KEZ45970.1 - 2.5e-47 159.8 0.4 3.6e-47 159.3 0.3 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KEZ45970.1 - 0.00018 20.3 0.1 0.00025 19.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Ctr PF04145.10 KEZ45971.1 - 2.5e-43 147.5 1.7 3.1e-43 147.2 1.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 KEZ45971.1 - 0.043 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) YfhO PF09586.5 KEZ45971.1 - 0.43 8.5 5.5 0.65 7.9 3.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Hemerythrin PF01814.18 KEZ45972.1 - 1.5e-06 28.4 0.2 1.8e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Chlorophyllase2 PF12740.2 KEZ45973.1 - 0.018 13.9 0.1 0.094 11.5 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KEZ45973.1 - 0.043 12.6 0.1 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Zip PF02535.17 KEZ45974.1 - 2.9e-48 164.5 0.0 4e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4095 PF13338.1 KEZ45975.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) NPR PF07391.6 KEZ45975.1 - 0.97 9.9 6.1 2.5 8.6 4.2 1.7 1 0 0 1 1 1 0 NPR nonapeptide repeat (2 copies) JAB PF01398.16 KEZ45976.1 - 1.3e-34 118.3 0.0 2.2e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KEZ45976.1 - 1.8e-26 92.4 1.3 3.7e-26 91.4 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KEZ45976.1 - 4.1e-09 35.9 0.0 6.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 KEZ45977.1 - 1.9e-72 244.2 0.2 7.6e-72 242.2 0.1 2.0 2 1 0 2 2 2 1 Histone deacetylase domain NACHT PF05729.7 KEZ45978.1 - 1.5e-06 28.0 0.0 3.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ45978.1 - 7.7e-06 26.0 2.2 2.1e-05 24.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.17 KEZ45978.1 - 0.00044 19.1 0.0 0.0011 17.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KEZ45978.1 - 0.001 19.1 0.5 0.018 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KEZ45978.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ArgK PF03308.11 KEZ45978.1 - 0.015 14.0 0.0 4.3 6.0 0.0 2.2 2 0 0 2 2 2 0 ArgK protein DUF2075 PF09848.4 KEZ45978.1 - 0.071 12.0 0.0 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.4 KEZ45978.1 - 0.1 11.5 0.1 0.31 9.9 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 zf-C2H2_4 PF13894.1 KEZ45978.1 - 2.5 8.6 9.1 0.25 11.7 1.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger SNF2_N PF00176.18 KEZ45979.1 - 1.1e-28 99.8 0.0 3.5e-16 58.8 0.1 2.1 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KEZ45979.1 - 8.5e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ45979.1 - 0.068 12.6 0.0 0.22 10.9 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase PPP4R2 PF09184.6 KEZ45981.1 - 5.8e-11 42.4 0.0 5.8e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 PPP4R2 PAT1 PF09770.4 KEZ45981.1 - 5 5.2 6.9 6.7 4.8 4.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 KEZ45982.1 - 6.4e-29 101.7 0.2 6.4e-29 101.7 0.1 7.5 2 1 3 5 5 2 1 AAA domain SbcCD_C PF13558.1 KEZ45982.1 - 3.9e-11 42.7 0.0 1.4e-10 40.8 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KEZ45982.1 - 2.3e-08 33.5 0.1 2.3e-08 33.5 0.1 2.6 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ45982.1 - 2.3e-07 31.1 16.4 8.2e-05 22.7 2.6 4.1 3 2 0 4 4 4 2 AAA domain AAA_13 PF13166.1 KEZ45982.1 - 3.5e-06 25.7 16.9 0.00024 19.7 0.1 6.6 3 2 3 6 6 6 3 AAA domain AAA_15 PF13175.1 KEZ45982.1 - 3.6e-06 26.2 10.6 3.6e-06 26.2 7.4 4.6 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.1 KEZ45982.1 - 0.0009 18.7 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 KEZ45982.1 - 0.028 14.1 1.1 0.092 12.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KEZ45982.1 - 0.068 13.4 0.0 0.068 13.4 0.0 6.6 4 2 0 5 5 3 0 ABC transporter AAA_19 PF13245.1 KEZ45982.1 - 0.12 12.1 0.1 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Strep_SA_rep PF06696.6 KEZ45982.1 - 2.4 8.0 13.6 17 5.3 0.1 5.2 4 0 0 4 4 4 0 Streptococcal surface antigen repeat PAS_3 PF08447.6 KEZ45983.1 - 4.2e-16 58.8 0.0 8.4e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold GATA PF00320.22 KEZ45983.1 - 7.3e-16 57.2 6.3 1.3e-15 56.4 4.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 KEZ45983.1 - 2.5e-08 34.1 0.1 6.7e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 KEZ45983.1 - 8.1e-07 28.9 0.0 2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 KEZ45983.1 - 2.3e-06 27.6 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KEZ45983.1 - 8.3e-06 25.5 0.0 2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold DMAP_binding PF06464.6 KEZ45983.1 - 0.013 16.1 3.9 0.046 14.3 1.2 2.3 2 0 0 2 2 2 0 DMAP1-binding Domain tRNA-synt_1c PF00749.16 KEZ45984.1 - 4.6e-34 117.4 0.2 5.6e-27 94.2 0.1 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KEZ45984.1 - 1.5e-19 70.3 0.0 5.9e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Rb_C PF08934.5 KEZ45985.1 - 0.07 12.7 1.2 0.14 11.7 0.8 1.5 1 0 0 1 1 1 0 Rb C-terminal domain TraG_N PF07916.6 KEZ45985.1 - 0.64 8.3 3.9 0.83 8.0 2.7 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Amidase PF01425.16 KEZ45986.1 - 3.5e-61 207.3 0.4 4.4e-61 207.0 0.3 1.1 1 0 0 1 1 1 1 Amidase Ank_2 PF12796.2 KEZ45987.1 - 1.1e-19 70.5 0.0 7.6e-10 38.9 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ45987.1 - 1.3e-18 65.7 0.0 4.4e-06 26.2 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KEZ45987.1 - 8.8e-13 48.3 0.1 0.00023 21.5 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ45987.1 - 1.3e-12 46.6 0.0 2.4e-05 24.1 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KEZ45987.1 - 3.7e-12 46.0 0.0 2.7e-06 27.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) vWA-TerF-like PF10138.4 KEZ45987.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Reo_sigmaC PF04582.7 KEZ45990.1 - 6.6e-07 28.8 42.0 0.00092 18.4 4.1 5.7 1 1 3 5 5 5 4 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 KEZ45990.1 - 0.00014 21.5 108.3 0.25 11.0 9.4 8.5 1 1 4 6 6 6 3 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 KEZ45990.1 - 0.0045 17.3 6.7 0.0045 17.3 4.7 9.2 1 1 7 10 10 10 3 Protein of unknown function (DUF972) ADIP PF11559.3 KEZ45990.1 - 0.0048 16.8 24.2 0.0085 16.0 5.2 9.9 1 1 8 10 10 10 5 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 KEZ45990.1 - 0.072 10.4 110.1 0.037 11.3 10.8 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KEZ45990.1 - 0.077 10.7 125.1 0.0044 14.8 48.5 3.8 1 1 1 3 3 3 0 Myosin tail Filament PF00038.16 KEZ45990.1 - 0.6 9.5 107.9 0.11 11.9 7.5 5.2 1 1 2 4 4 4 0 Intermediate filament protein HeLo PF14479.1 KEZ45991.1 - 7.2e-26 91.2 0.0 1.7e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation Vps8 PF12816.2 KEZ45992.1 - 5.8e-70 234.5 0.0 1.1e-69 233.6 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.1 KEZ45992.1 - 0.0012 18.6 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 Ring finger domain Clathrin PF00637.15 KEZ45992.1 - 0.0028 17.2 0.3 2.5 7.6 0.0 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 KEZ45992.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEZ45992.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ45993.1 - 5.3e-13 48.5 7.0 8.3e-13 47.9 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEZ45993.1 - 6.6e-08 32.0 3.8 1.1e-07 31.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEZ45993.1 - 2.9e-07 30.4 5.0 6.2e-07 29.4 3.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KEZ45993.1 - 1.5e-05 24.5 4.0 2.5e-05 23.9 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEZ45993.1 - 3e-05 23.9 5.6 4.8e-05 23.2 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KEZ45993.1 - 5.2e-05 22.8 2.7 7.9e-05 22.2 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEZ45993.1 - 0.0025 17.6 3.4 0.0053 16.5 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEZ45993.1 - 0.01 15.4 6.3 0.018 14.6 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Neur_chan_memb PF02932.11 KEZ45993.1 - 0.098 12.5 2.0 0.44 10.3 1.4 2.0 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PHD PF00628.24 KEZ45993.1 - 0.15 11.7 5.8 0.28 10.9 4.0 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 KEZ45993.1 - 0.34 10.8 3.0 0.87 9.5 2.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 KEZ45993.1 - 0.58 10.0 4.7 1.1 9.1 3.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KEZ45993.1 - 2.2 8.4 5.5 4.1 7.5 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain PPP4R2 PF09184.6 KEZ45993.1 - 2.9 7.3 11.2 5.4 6.4 7.8 1.3 1 0 0 1 1 1 0 PPP4R2 Prok-RING_1 PF14446.1 KEZ45993.1 - 3.1 7.6 8.9 14 5.5 5.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Senescence_reg PF04520.8 KEZ45993.1 - 5.8 7.3 17.8 1.7 9.0 8.1 2.4 2 0 0 2 2 2 0 Senescence regulator Cwf_Cwc_15 PF04889.7 KEZ45993.1 - 8.9 5.9 12.7 15 5.1 8.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pro_isomerase PF00160.16 KEZ45994.1 - 1.4e-49 168.2 0.7 1.6e-49 168.0 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TEA PF01285.13 KEZ45995.1 - 4.6e-13 49.1 0.0 7.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family RRM_1 PF00076.17 KEZ45996.1 - 4.1e-74 244.1 0.3 5.1e-18 64.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ45996.1 - 1.2e-71 236.5 0.3 1.8e-16 59.8 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ45996.1 - 1.1e-33 114.7 0.0 8.5e-08 31.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ45996.1 - 2e-05 24.2 0.0 7.3 6.4 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KEZ45996.1 - 5.1e-05 22.9 0.1 2.8 7.7 0.0 4.8 4 0 0 4 4 4 2 Limkain b1 RRM_3 PF08777.6 KEZ45996.1 - 7.5e-05 22.5 1.1 0.19 11.5 0.0 4.7 5 1 0 5 5 5 1 RNA binding motif Dynein_light PF01221.13 KEZ45997.1 - 1.2e-29 102.0 6.4 4.8e-29 100.1 4.5 1.7 1 1 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 KEZ45997.1 - 0.02 14.4 0.1 0.042 13.4 0.0 1.4 1 1 0 1 1 1 0 Immunity protein 28 DUF1852 PF08908.6 KEZ45997.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) DASH_Dad3 PF08656.5 KEZ45998.1 - 0.17 11.6 0.0 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 Methyltransf_16 PF10294.4 KEZ45999.1 - 9.3e-19 67.5 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEZ45999.1 - 0.0019 18.7 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ45999.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ45999.1 - 0.087 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ45999.1 - 0.1 12.2 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_N PF01194.12 KEZ46001.1 - 6e-30 103.0 1.0 7e-30 102.8 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 KEZ46002.1 - 6.9e-10 38.4 1.0 0.00083 19.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KEZ46002.1 - 0.024 14.9 0.2 0.63 10.4 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain PQQ PF01011.16 KEZ46002.1 - 0.055 13.0 0.6 0.73 9.4 0.1 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat DIOX_N PF14226.1 KEZ46003.1 - 5.4e-31 107.5 0.0 7.1e-30 103.9 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KEZ46003.1 - 1.4e-15 57.3 0.0 2.5e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PsbP PF01789.11 KEZ46003.1 - 0.18 11.2 0.0 0.44 9.9 0.0 1.6 2 0 0 2 2 2 0 PsbP zf-met2 PF12907.2 KEZ46004.1 - 6.6e-15 54.7 3.6 9.8e-15 54.2 2.5 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KEZ46004.1 - 5.7e-06 26.9 8.9 1e-05 26.1 6.1 1.4 1 0 0 1 1 1 1 4F5 protein family HECT_2 PF09814.4 KEZ46004.1 - 0.018 13.8 1.1 0.019 13.6 0.8 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HHH PF00633.18 KEZ46005.1 - 0.00051 19.5 0.3 0.0016 18.0 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KEZ46005.1 - 0.011 15.9 0.1 0.087 13.0 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain Bap31 PF05529.7 KEZ46006.1 - 1.9e-63 213.4 6.8 2.4e-63 213.1 4.7 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TBPIP PF07106.8 KEZ46006.1 - 0.0084 15.6 2.1 0.012 15.1 1.4 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF192 PF02643.10 KEZ46006.1 - 0.0085 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Spc7 PF08317.6 KEZ46006.1 - 0.015 14.0 1.7 0.02 13.5 1.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.3 KEZ46006.1 - 0.028 14.3 1.3 0.041 13.7 0.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.4 KEZ46006.1 - 0.035 12.5 1.3 0.043 12.2 0.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4446 PF14584.1 KEZ46006.1 - 0.051 13.3 0.9 0.092 12.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Uds1 PF15456.1 KEZ46006.1 - 0.072 13.0 0.6 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Prefoldin_2 PF01920.15 KEZ46006.1 - 0.079 12.7 3.6 0.11 12.2 2.1 1.5 1 1 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 KEZ46006.1 - 0.079 12.5 1.9 0.13 11.8 1.3 1.3 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 KEZ46006.1 - 0.081 12.6 3.3 0.085 12.5 1.6 1.6 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 HALZ PF02183.13 KEZ46006.1 - 0.097 12.3 4.3 0.099 12.3 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Phage_GP20 PF06810.6 KEZ46006.1 - 0.13 11.6 4.4 0.14 11.5 2.5 1.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Lge1 PF11488.3 KEZ46006.1 - 0.21 11.8 1.5 0.38 10.9 1.0 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DivIC PF04977.10 KEZ46006.1 - 0.4 10.2 6.8 0.19 11.2 1.6 2.7 2 1 1 3 3 3 0 Septum formation initiator CCDC-167 PF15188.1 KEZ46006.1 - 0.82 9.6 4.6 0.68 9.9 1.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SET PF00856.23 KEZ46007.1 - 1.1e-22 81.0 0.6 5.2e-22 78.8 0.1 2.5 2 1 0 2 2 2 1 SET domain Pil1 PF13805.1 KEZ46008.1 - 1.1e-149 496.9 0.6 1.4e-149 496.6 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KEZ46008.1 - 0.01 15.1 1.1 0.03 13.6 0.8 1.8 2 1 0 2 2 2 0 FAM92 protein Laminin_II PF06009.7 KEZ46008.1 - 0.018 14.8 0.3 0.098 12.4 0.0 2.2 1 1 1 2 2 2 0 Laminin Domain II FlgN PF05130.7 KEZ46008.1 - 2.2 8.5 7.0 1.3 9.3 0.5 3.0 2 2 1 3 3 3 0 FlgN protein UPF0167 PF03691.9 KEZ46009.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0167) zf-C2H2_jaz PF12171.3 KEZ46009.1 - 0.045 13.9 0.4 0.095 12.8 0.1 1.7 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ46009.1 - 0.072 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEZ46009.1 - 0.15 12.4 7.7 2 8.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Peroxin-13_N PF04088.8 KEZ46010.1 - 3.5e-58 196.0 0.0 5.2e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KEZ46010.1 - 5.9e-07 28.8 0.0 9.6e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KEZ46010.1 - 5.3e-06 25.7 0.0 1.1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 SH3 domain ADH_N PF08240.7 KEZ46011.1 - 1.1e-28 99.1 0.9 2.2e-28 98.1 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ46011.1 - 3e-17 62.4 0.0 4.8e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 KEZ46011.1 - 0.0084 15.8 0.1 0.4 10.4 0.0 2.8 3 0 0 3 3 3 1 S1-like ATP-synt_G PF04718.10 KEZ46012.1 - 6.4e-25 87.7 0.6 2.3e-24 85.9 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Methyltransf_23 PF13489.1 KEZ46013.1 - 2.2e-14 53.4 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46013.1 - 0.00024 21.6 0.0 0.00049 20.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46013.1 - 0.00036 20.9 0.0 0.0022 18.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ46013.1 - 0.00068 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 KEZ46013.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ46013.1 - 0.0036 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KEZ46013.1 - 0.027 14.9 0.0 0.26 11.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KEZ46013.1 - 0.047 13.6 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KEZ46013.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KEZ46013.1 - 0.074 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CaM_binding PF07839.6 KEZ46013.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Plant calmodulin-binding domain TFIIA PF03153.8 KEZ46014.1 - 4.8e-77 260.4 5.5 9e-77 259.4 3.8 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 KEZ46014.1 - 0.17 11.5 2.5 0.24 11.0 1.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.27 KEZ46015.1 - 1.7e-24 84.7 19.3 1.6e-06 27.7 0.1 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 KEZ46015.1 - 2.9e-06 27.1 0.2 0.00017 21.3 0.1 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 KEZ46015.1 - 0.024 14.1 0.0 0.53 9.8 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Kelch_4 PF13418.1 KEZ46016.1 - 4.8e-28 96.6 4.3 5.3e-08 32.4 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KEZ46016.1 - 2.2e-25 87.7 5.8 3e-06 27.1 0.1 6.7 6 1 1 7 7 7 4 Kelch motif Kelch_5 PF13854.1 KEZ46016.1 - 5.6e-25 86.8 0.3 4e-07 29.8 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 KEZ46016.1 - 1.2e-23 82.6 2.7 7.9e-08 32.2 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 KEZ46016.1 - 3.3e-22 77.7 0.1 3e-07 29.8 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 KEZ46016.1 - 1.4e-20 72.2 0.6 6.6e-06 25.6 0.0 4.8 4 0 0 4 4 4 3 Kelch motif BTB PF00651.26 KEZ46016.1 - 2e-08 34.2 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KEZ46017.1 - 7.9e-06 25.8 12.8 0.1 12.9 0.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ46017.1 - 0.00039 20.6 14.8 0.17 12.2 1.3 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KEZ46017.1 - 0.00045 20.2 7.0 0.0097 16.0 0.3 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KEZ46017.1 - 0.032 14.5 12.4 0.033 14.5 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 KEZ46017.1 - 1 9.6 11.4 0.27 11.4 1.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HIG_1_N PF04588.8 KEZ46018.1 - 6.5e-06 25.7 2.4 6.5e-06 25.7 1.7 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Romo1 PF10247.4 KEZ46018.1 - 0.04 14.1 1.2 0.081 13.1 0.8 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Polysacc_synt_3 PF13440.1 KEZ46018.1 - 0.29 10.5 4.9 5 6.5 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Dus PF01207.12 KEZ46019.1 - 6.9e-39 133.5 0.0 8e-27 93.8 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Metallophos PF00149.23 KEZ46020.1 - 2.3e-39 134.9 0.1 3.2e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_5 PF13857.1 KEZ46021.1 - 8.6e-11 41.7 0.2 0.0013 18.9 0.0 5.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEZ46021.1 - 2.6e-09 37.2 0.0 1.8e-05 24.9 0.0 4.0 1 1 3 4 4 4 2 Ankyrin repeats (3 copies) NACHT PF05729.7 KEZ46021.1 - 2.4e-08 33.7 0.1 5.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ46021.1 - 6.4e-07 29.5 0.4 3.5e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Ank_4 PF13637.1 KEZ46021.1 - 1.1e-06 28.9 0.1 0.00077 19.9 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 KEZ46021.1 - 1.1e-06 28.7 0.0 3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ank PF00023.25 KEZ46021.1 - 1.7e-05 24.3 0.2 4.2 7.3 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat KAP_NTPase PF07693.9 KEZ46021.1 - 0.0019 17.2 0.0 0.017 14.1 0.0 2.0 1 1 0 2 2 2 1 KAP family P-loop domain Ank_3 PF13606.1 KEZ46021.1 - 0.0065 16.6 0.1 11 6.6 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat TrwB_AAD_bind PF10412.4 KEZ46021.1 - 0.11 11.1 0.0 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RRF PF01765.14 KEZ46022.1 - 3.8e-22 78.5 0.4 7.3e-22 77.5 0.3 1.5 1 0 0 1 1 1 1 Ribosome recycling factor WD40 PF00400.27 KEZ46022.1 - 2.7e-21 74.6 14.4 1.1e-08 34.6 0.1 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat Nup160 PF11715.3 KEZ46022.1 - 0.0076 14.4 0.0 2.7 6.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 XH PF03469.9 KEZ46022.1 - 0.12 12.0 1.6 0.23 11.1 1.1 1.3 1 0 0 1 1 1 0 XH domain Aldedh PF00171.17 KEZ46023.1 - 7.4e-161 535.5 0.5 8.7e-161 535.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HATPase_c PF02518.21 KEZ46024.1 - 1.7e-24 85.6 0.4 7.4e-24 83.6 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KEZ46024.1 - 2.2e-20 72.7 0.0 5e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KEZ46024.1 - 1.4e-12 47.9 0.0 2e-07 31.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KEZ46024.1 - 1.2e-09 38.1 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 2 PAS fold HisKA PF00512.20 KEZ46024.1 - 1.1e-06 28.5 0.0 4.6e-06 26.5 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KEZ46024.1 - 4e-06 26.5 0.0 7.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.6 KEZ46024.1 - 0.00034 20.6 1.3 0.0013 18.7 0.2 2.5 2 0 0 2 2 2 1 PAS fold PH_6 PF15406.1 KEZ46025.1 - 1.8e-37 127.8 4.5 1.8e-37 127.8 3.1 3.8 4 1 1 5 5 5 1 Pleckstrin homology domain PH PF00169.24 KEZ46025.1 - 0.1 12.8 0.1 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 PH domain tRNA-synt_2 PF00152.15 KEZ46026.1 - 1.6e-68 230.9 0.0 1.1e-51 175.5 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KEZ46026.1 - 6.5e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KEZ46026.1 - 0.00011 21.4 0.0 0.031 13.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Actin PF00022.14 KEZ46027.1 - 1.1e-141 471.7 0.0 1.3e-141 471.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KEZ46027.1 - 6.1e-06 25.0 0.0 0.0027 16.3 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 KEZ46027.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase SRF-TF PF00319.13 KEZ46028.1 - 4.8e-23 80.1 0.1 8.4e-23 79.3 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Fungal_trans PF04082.13 KEZ46029.1 - 3.7e-19 68.6 0.1 5.4e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46029.1 - 3e-08 33.4 9.4 4.9e-08 32.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CK2S PF15011.1 KEZ46029.1 - 0.043 13.6 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate Fungal_trans PF04082.13 KEZ46030.1 - 2.5e-14 52.8 0.0 3.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VPS9 PF02204.13 KEZ46031.1 - 8.6e-20 70.7 0.0 1.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KEZ46031.1 - 5e-09 35.4 0.1 5.6e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 CUE domain E1-E2_ATPase PF00122.15 KEZ46032.1 - 6e-17 61.4 0.0 1.1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KEZ46032.1 - 1.1e-15 58.6 0.4 8.5e-12 45.9 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KEZ46032.1 - 1.1e-13 51.8 0.1 1.7e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ46032.1 - 2.8e-11 43.1 0.0 9.9e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KEZ46032.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4254 PF14063.1 KEZ46032.1 - 0.02 14.5 0.6 0.042 13.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) MFS_1 PF07690.11 KEZ46033.1 - 1.3e-40 139.1 59.6 1.4e-40 139.1 36.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Dispanin PF04505.7 KEZ46033.1 - 0.38 10.3 0.0 0.38 10.3 0.0 3.6 3 0 0 3 3 3 0 Interferon-induced transmembrane protein Tmemb_18A PF09771.4 KEZ46033.1 - 0.73 9.8 6.4 0.38 10.7 1.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 188 AAA PF00004.24 KEZ46034.1 - 1.6e-17 63.9 0.0 2.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ46034.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ46034.1 - 0.00017 21.7 0.0 0.00067 19.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ46034.1 - 0.00022 20.9 0.0 0.00055 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KEZ46034.1 - 0.00029 20.5 0.2 0.00059 19.5 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KEZ46034.1 - 0.00059 20.6 0.4 0.012 16.4 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KEZ46034.1 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KEZ46034.1 - 0.017 14.6 0.1 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KEZ46034.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KEZ46034.1 - 0.021 15.1 0.1 0.17 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KEZ46034.1 - 0.028 13.8 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 KEZ46034.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 KEZ46034.1 - 0.051 13.1 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KEZ46034.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEZ46034.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KEZ46034.1 - 0.12 12.3 0.1 0.39 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KEZ46034.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_2 PF07724.9 KEZ46034.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) SNF5 PF04855.7 KEZ46035.1 - 5.5e-83 278.1 0.0 8.5e-83 277.5 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 TPR_11 PF13414.1 KEZ46036.1 - 6.2e-12 44.9 0.0 2.2e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_21 PF09976.4 KEZ46036.1 - 1.5e-05 24.9 0.2 2.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46036.1 - 2.1e-05 23.9 0.0 0.0046 16.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.3 KEZ46036.1 - 2.1e-05 23.5 0.1 3.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 KEZ46036.1 - 2.3e-05 24.1 0.0 6.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46036.1 - 4.5e-05 22.8 0.0 0.015 14.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46036.1 - 5.5e-05 22.7 0.0 0.041 13.7 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46036.1 - 0.0002 21.9 1.6 0.25 12.0 0.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46036.1 - 0.0017 18.6 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ46036.1 - 0.017 15.7 1.2 2.1 9.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KEZ46036.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KEZ46036.1 - 0.059 13.3 0.3 2.5 8.0 0.0 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_7 PF00840.15 KEZ46037.1 - 4.5e-215 713.9 26.7 5.5e-215 713.6 18.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KEZ46037.1 - 1.7e-15 56.3 10.6 1.7e-15 56.3 7.3 5.0 6 1 0 6 6 6 1 Fungal cellulose binding domain UBA PF00627.26 KEZ46038.1 - 0.00068 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 KEZ46038.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain Glyco_hydro_7 PF00840.15 KEZ46039.1 - 2.1e-192 639.2 9.7 2.5e-192 639.0 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Hexapep PF00132.19 KEZ46040.1 - 7e-09 34.8 1.0 1.6e-05 24.2 0.4 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KEZ46040.1 - 7.4e-05 22.8 0.0 0.00028 21.0 0.0 1.9 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KEZ46040.1 - 0.00086 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase YxiJ PF14176.1 KEZ46040.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 YxiJ-like protein Fucokinase PF07959.7 KEZ46040.1 - 0.11 11.0 0.5 0.17 10.4 0.3 1.2 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 KEZ46040.1 - 0.27 10.8 7.4 2.8 7.5 3.7 2.9 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-C2H2 PF00096.21 KEZ46041.1 - 5.4e-06 26.4 13.3 0.0022 18.2 2.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ46041.1 - 0.0002 21.4 11.2 0.023 15.0 2.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger LRR_4 PF12799.2 KEZ46042.1 - 8.8e-05 22.0 0.1 3 7.5 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KEZ46042.1 - 0.00023 20.8 0.3 0.98 9.6 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeat F-box-like PF12937.2 KEZ46042.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 KEZ46042.1 - 0.077 12.7 0.1 3.6 7.4 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 KEZ46042.1 - 0.36 11.1 6.0 24 5.7 0.1 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KEZ46042.1 - 0.38 10.9 4.3 15 6.1 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat Ribosomal_S8e PF01201.17 KEZ46043.1 - 3.1e-48 163.2 1.3 3.7e-48 163.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e HECT PF00632.20 KEZ46044.1 - 1.4e-99 333.2 0.1 2.3e-99 332.5 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 KEZ46044.1 - 6e-96 321.4 0.0 6e-96 321.4 0.0 3.7 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KEZ46044.1 - 2e-76 257.3 0.0 2e-76 257.3 0.0 3.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KEZ46044.1 - 1.1e-31 108.9 8.6 1.1e-31 108.9 6.0 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) RabGAP-TBC PF00566.13 KEZ46045.1 - 1.9e-46 158.2 9.3 2.6e-46 157.8 0.0 3.3 4 0 0 4 4 4 2 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 KEZ46045.1 - 1.8 8.4 22.5 0.063 13.1 3.5 3.9 3 0 0 3 3 3 0 Microtubule associated DUF1640 PF07798.6 KEZ46045.1 - 7.5 6.5 21.2 22 5.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Fungal_trans PF04082.13 KEZ46046.1 - 4.8e-12 45.2 0.3 9.6e-12 44.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46046.1 - 2.7e-05 23.9 9.1 4.3e-05 23.3 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rotavirus_VP3 PF06929.6 KEZ46046.1 - 0.069 11.0 0.1 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein DUF1814 PF08843.6 KEZ46047.1 - 1.9e-07 31.1 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NTP_transf_5 PF14907.1 KEZ46047.1 - 0.046 13.0 0.3 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase DOCK-C2 PF14429.1 KEZ46048.1 - 5.3e-20 71.8 0.0 9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KEZ46048.1 - 2e-11 43.5 0.1 5.7e-11 42.0 0.1 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KEZ46048.1 - 1.2e-05 24.5 0.0 2.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KEZ46048.1 - 0.0022 17.5 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 KEZ46048.1 - 0.073 12.5 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain DUF4360 PF14273.1 KEZ46049.1 - 1.3e-16 60.7 0.0 4e-16 59.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) DUF2407_C PF13373.1 KEZ46051.1 - 1.8e-32 112.1 0.3 4.1e-32 111.0 0.2 1.6 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 KEZ46051.1 - 3.9e-23 81.4 0.0 1.6e-22 79.5 0.0 2.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ras PF00071.17 KEZ46051.1 - 2.4e-08 33.5 0.0 3.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Ras family ubiquitin PF00240.18 KEZ46051.1 - 0.059 12.7 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family rRNA_proc-arch PF13234.1 KEZ46052.1 - 2.5e-89 299.0 0.0 3.9e-89 298.3 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KEZ46052.1 - 3.6e-59 199.0 3.3 5.1e-59 198.5 1.4 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KEZ46052.1 - 1.3e-20 73.6 0.0 6e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ46052.1 - 1.9e-06 27.6 0.0 4.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ46052.1 - 0.0081 16.0 0.0 0.087 12.6 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KEZ46052.1 - 0.072 12.7 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase Cyt-b5 PF00173.23 KEZ46054.1 - 1.5e-08 34.3 0.0 2.9e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GPP34 PF05719.6 KEZ46054.1 - 0.28 11.2 2.7 0.46 10.5 1.9 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) CENP-X PF09415.5 KEZ46056.1 - 2.6e-22 78.3 0.2 3.6e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 KEZ46056.1 - 0.085 12.9 0.1 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AurF PF11583.3 KEZ46056.1 - 0.1 11.5 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Mito_carr PF00153.22 KEZ46057.1 - 6.4e-68 224.5 3.5 9.9e-25 86.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 KEZ46058.1 - 4.1e-40 136.0 4.3 4.5e-40 135.9 3.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 KEZ46058.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 MarR family TrmB PF01978.14 KEZ46058.1 - 0.0087 15.7 0.3 0.012 15.3 0.2 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 KEZ46058.1 - 0.01 15.1 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RNA_pol_Rpc34 PF05158.7 KEZ46058.1 - 0.011 14.9 0.1 0.019 14.1 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 KEZ46058.1 - 0.012 15.7 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Fe_dep_repress PF01325.14 KEZ46058.1 - 0.043 13.7 0.1 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.1 KEZ46058.1 - 0.093 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Ribosomal_S7 PF00177.16 KEZ46059.1 - 3.9e-41 140.0 1.6 4.8e-41 139.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NPP1 PF05630.6 KEZ46060.1 - 6.9e-60 202.3 0.0 8e-60 202.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) BTB_2 PF02214.17 KEZ46061.1 - 6.3e-07 29.5 0.1 0.00058 20.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Pyridoxal_deC PF00282.14 KEZ46062.1 - 4.2e-73 245.9 0.0 5.6e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KEZ46062.1 - 2.8e-07 29.6 0.0 4.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEZ46062.1 - 0.0064 15.5 0.4 0.12 11.4 0.1 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 KEZ46062.1 - 0.067 11.7 0.0 0.28 9.6 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Abhydrolase_3 PF07859.8 KEZ46063.1 - 8.7e-36 123.4 0.0 3.6e-25 88.7 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KEZ46063.1 - 0.19 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Aminotran_3 PF00202.16 KEZ46064.1 - 4.3e-92 308.5 0.0 5.2e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KEZ46064.1 - 0.0047 15.9 0.0 0.0071 15.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Ufd2P_core PF10408.4 KEZ46065.1 - 3.7e-190 633.3 0.2 4.6e-190 633.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KEZ46065.1 - 1.1e-24 86.1 0.8 4.1e-24 84.3 0.6 2.0 1 0 0 1 1 1 1 U-box domain Peptidase_C2 PF00648.16 KEZ46066.1 - 1.8e-57 194.6 6.2 6.4e-38 130.4 1.5 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease Corona_nucleoca PF00937.13 KEZ46066.1 - 0.0045 16.0 4.5 0.0045 16.0 3.1 3.3 3 0 0 3 3 3 1 Coronavirus nucleocapsid protein SPO22 PF08631.5 KEZ46067.1 - 4.3e-52 176.9 3.8 1e-49 169.0 0.1 3.4 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 KEZ46067.1 - 1.9e-08 34.1 2.3 4.5e-05 23.2 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46067.1 - 5 7.2 12.4 0.75 9.8 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PAS PF00989.19 KEZ46068.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Ald_Xan_dh_C2 PF02738.13 KEZ46069.1 - 1.7e-193 643.9 0.2 2.3e-193 643.4 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KEZ46069.1 - 1.7e-49 167.5 0.0 3.3e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 KEZ46069.1 - 1.2e-31 109.0 0.0 2.8e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 KEZ46069.1 - 2.3e-29 101.3 0.8 1e-28 99.2 0.1 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 KEZ46069.1 - 2e-28 98.1 0.3 5.1e-28 96.7 0.0 1.9 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.22 KEZ46069.1 - 1.7e-08 34.0 1.2 3.6e-08 33.0 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 KEZ46069.1 - 0.04 13.4 0.2 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 DUF218 domain DUF3598 PF12204.3 KEZ46069.1 - 0.29 10.3 0.0 0.52 9.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) APH PF01636.18 KEZ46070.1 - 1.5e-07 31.4 0.1 7.5e-07 29.1 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Aldedh PF00171.17 KEZ46071.1 - 3.3e-135 451.0 0.0 4e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nucleo_LEF-12 PF06256.6 KEZ46071.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus LEF-12 protein LuxC PF05893.9 KEZ46071.1 - 0.012 14.3 0.1 0.29 9.7 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Big_1 PF02369.11 KEZ46071.1 - 0.067 13.1 0.1 0.28 11.1 0.1 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Aminotran_1_2 PF00155.16 KEZ46072.1 - 2.1e-68 230.9 0.0 2.4e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEZ46072.1 - 4.1e-05 22.7 0.0 7.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KEZ46072.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KEZ46072.1 - 0.0011 17.3 0.0 0.0019 16.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KEZ46072.1 - 0.0094 14.7 0.0 0.019 13.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Steroid_dh PF02544.11 KEZ46073.1 - 4.2e-20 72.0 2.3 7e-19 68.0 1.6 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEZ46073.1 - 3.5e-05 23.1 1.2 5.8e-05 22.5 0.4 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) DUF544 PF04424.8 KEZ46074.1 - 8.6e-15 54.6 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DnaJ PF00226.26 KEZ46075.1 - 8.8e-22 76.6 0.2 1.5e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KEZ46075.1 - 1.6e-20 73.2 0.1 7.7e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DUF2416 PF10315.4 KEZ46076.1 - 1.1e-05 25.5 0.2 7.7e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) DUF4536 PF15055.1 KEZ46076.1 - 0.014 15.4 0.4 0.063 13.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4536) Y_phosphatase2 PF03162.8 KEZ46077.1 - 1.1e-41 142.0 0.0 1.5e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KEZ46077.1 - 3e-10 40.6 0.3 8.4e-10 39.1 0.0 1.9 2 1 1 3 3 3 1 Tyrosine phosphatase family DSPc PF00782.15 KEZ46077.1 - 2e-05 24.1 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KEZ46077.1 - 7e-05 22.2 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 KEZ46077.1 - 0.056 12.2 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Ima1_N PF09779.4 KEZ46078.1 - 4.8e-25 88.5 2.8 4.8e-25 88.5 1.9 1.7 2 0 0 2 2 2 1 Ima1 N-terminal domain MRP-S25 PF13741.1 KEZ46079.1 - 1.2e-68 231.0 11.0 2.6e-66 223.4 7.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 ACTH_domain PF00976.13 KEZ46079.1 - 0.34 10.8 1.8 7 6.5 0.0 2.5 2 0 0 2 2 2 0 Corticotropin ACTH domain COX7C PF02935.11 KEZ46080.1 - 4.6e-15 55.1 0.7 4.9e-15 55.0 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Frataxin_Cyay PF01491.11 KEZ46081.1 - 1.9e-18 66.2 1.6 5.9e-12 45.3 0.0 2.1 1 1 1 2 2 2 2 Frataxin-like domain Beta-lactamase PF00144.19 KEZ46081.1 - 0.063 12.2 0.1 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase MMR_HSR1 PF01926.18 KEZ46082.1 - 6.1e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEZ46082.1 - 1.9e-05 23.9 0.0 3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KEZ46082.1 - 0.0062 15.7 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ46082.1 - 0.009 16.0 0.3 0.032 14.2 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 KEZ46082.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KEZ46082.1 - 0.013 15.8 0.2 0.032 14.5 0.1 1.7 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KEZ46082.1 - 0.034 14.9 0.0 0.081 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KEZ46082.1 - 0.042 12.7 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FeoB_N PF02421.13 KEZ46082.1 - 0.048 12.9 0.0 0.71 9.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.1 KEZ46082.1 - 0.076 12.5 0.2 0.076 12.5 0.2 2.3 2 1 1 3 3 3 0 AAA domain ArgK PF03308.11 KEZ46082.1 - 0.087 11.5 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 KEZ46082.1 - 0.1 12.9 0.1 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KEZ46082.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KEZ46082.1 - 0.3 10.6 2.9 0.19 11.2 0.3 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Methyltrans_RNA PF04452.9 KEZ46083.1 - 0.066 12.3 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Clat_adaptor_s PF01217.15 KEZ46084.1 - 1.8e-31 108.7 0.0 3.3e-31 107.9 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_1 PF00133.17 KEZ46085.1 - 8.1e-42 143.0 0.0 4.2e-34 117.5 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KEZ46085.1 - 2e-17 62.9 0.4 8.3e-10 37.8 0.0 4.0 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KEZ46085.1 - 6.9e-13 48.6 0.2 1.7e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KEZ46085.1 - 1.4e-06 27.6 0.0 2.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain zf-CSL PF05207.8 KEZ46086.1 - 3e-25 87.4 1.0 3.8e-25 87.1 0.7 1.1 1 0 0 1 1 1 1 CSL zinc finger Terminase_GpA PF05876.7 KEZ46086.1 - 0.0039 15.6 0.2 0.0046 15.3 0.1 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) DUF4109 PF13397.1 KEZ46086.1 - 0.14 12.5 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) Zn-ribbon_8 PF09723.5 KEZ46086.1 - 0.23 11.4 3.1 0.53 10.2 2.1 1.6 1 1 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 KEZ46086.1 - 0.42 9.9 3.0 0.22 10.8 0.5 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding ABC_membrane_2 PF06472.10 KEZ46087.1 - 2.4e-108 361.5 2.0 4.3e-108 360.7 1.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KEZ46087.1 - 1.1e-18 67.8 0.0 2.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KEZ46087.1 - 0.00077 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ46087.1 - 0.013 15.5 0.8 0.047 13.6 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KEZ46087.1 - 0.037 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KEZ46087.1 - 0.074 13.3 0.2 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KEZ46087.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 KEZ46087.1 - 0.091 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 KEZ46087.1 - 0.1 11.7 0.1 0.42 9.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IBR PF01485.16 KEZ46088.1 - 3.2e-18 65.3 22.9 5.1e-11 42.2 3.1 3.6 3 1 0 3 3 3 2 IBR domain Stc1 PF12898.2 KEZ46088.1 - 0.032 14.2 1.0 0.032 14.2 0.7 3.7 3 1 0 3 3 3 0 Stc1 domain K_channel_TID PF07941.6 KEZ46088.1 - 3.9 7.7 8.6 7.8 6.7 0.0 3.6 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain YhfH PF14149.1 KEZ46088.1 - 4 7.3 14.4 1.6 8.5 2.5 3.5 3 0 0 3 3 3 0 YhfH-like protein DNA_ligase_ZBD PF03119.11 KEZ46088.1 - 7.9 6.2 9.1 0.44 10.2 0.2 3.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain HSP70 PF00012.15 KEZ46089.1 - 0.0013 16.7 2.0 0.017 13.0 0.0 2.8 3 1 0 3 3 3 2 Hsp70 protein JmjC PF02373.17 KEZ46090.1 - 2.2e-37 127.7 0.3 5.4e-37 126.5 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 KEZ46090.1 - 4.6e-18 65.1 3.1 9.6e-18 64.1 2.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KEZ46090.1 - 6e-18 64.8 3.8 1.1e-17 64.0 2.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 KEZ46090.1 - 2.6e-14 52.4 1.4 2.6e-14 52.4 1.0 2.3 2 0 0 2 2 2 1 jmjN domain PAP2 PF01569.16 KEZ46091.1 - 1.7e-18 66.5 1.4 5e-18 65.0 1.0 1.8 1 0 0 1 1 1 1 PAP2 superfamily adh_short PF00106.20 KEZ46092.1 - 2.7e-21 76.2 0.7 7.4e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ46092.1 - 7.1e-12 45.6 0.0 1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ46092.1 - 2.3e-08 33.9 2.9 1.5e-07 31.2 2.0 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KEZ46092.1 - 6.7e-06 26.2 1.9 9.4e-06 25.7 1.3 1.3 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KEZ46092.1 - 8.4e-06 25.5 0.5 1.4e-05 24.8 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KEZ46092.1 - 0.00013 21.4 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KEZ46092.1 - 0.0011 19.2 0.1 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.16 KEZ46092.1 - 0.0052 16.2 0.6 0.021 14.2 0.2 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KEZ46092.1 - 0.01 15.1 0.2 0.014 14.6 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family RHH_2 PF03693.9 KEZ46092.1 - 0.015 15.4 0.4 1.9 8.7 0.0 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0156) DFP PF04127.10 KEZ46092.1 - 0.017 14.7 0.2 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 KEZ46092.1 - 0.021 15.2 0.5 0.049 14.0 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 KEZ46092.1 - 0.024 13.7 0.1 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.19 KEZ46092.1 - 0.026 13.4 1.7 0.13 11.1 0.4 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 KEZ46092.1 - 0.064 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 KEZ46092.1 - 0.07 12.0 0.2 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 KEZ46092.1 - 0.072 12.8 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_4 PF07993.7 KEZ46092.1 - 0.084 11.7 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein ThiF PF00899.16 KEZ46093.1 - 1.8e-40 137.9 0.1 4.1e-40 136.7 0.1 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KEZ46093.1 - 3.3e-29 100.2 0.3 7.9e-29 99.0 0.2 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KEZ46093.1 - 9.8e-20 70.4 1.6 9.8e-20 70.4 1.1 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KEZ46093.1 - 1.5e-19 69.1 0.5 3.5e-19 67.8 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KEZ46093.1 - 0.00044 20.3 0.0 0.00094 19.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KEZ46093.1 - 0.0023 18.1 0.0 0.0084 16.3 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding MoeZ_MoeB PF05237.8 KEZ46093.1 - 0.11 12.1 0.9 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 MoeZ/MoeB domain DUF2419 PF10343.4 KEZ46094.1 - 8.4e-130 432.1 0.0 1e-129 431.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DNA_pol_delta_4 PF04081.8 KEZ46095.1 - 3.8e-27 95.0 8.8 3.5e-26 91.9 6.1 2.2 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 WD40 PF00400.27 KEZ46095.1 - 8.9e-25 85.6 14.6 4.6e-10 38.9 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 KEZ46095.1 - 3.9e-12 46.1 6.4 1e-11 44.7 4.4 1.7 1 0 0 1 1 1 1 Ribosomal L32p protein family eIF2A PF08662.6 KEZ46095.1 - 0.013 15.2 0.1 0.081 12.6 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KEZ46095.1 - 0.041 12.1 0.1 0.14 10.3 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain Pox_Ag35 PF03286.9 KEZ46095.1 - 0.17 11.3 5.2 0.53 9.7 3.5 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SMI1_KNR4 PF09346.5 KEZ46095.1 - 0.19 11.7 0.3 2.5 8.1 0.0 2.4 1 1 1 2 2 2 0 SMI1 / KNR4 family (SUKH-1) Septin PF00735.13 KEZ46096.1 - 3.6e-113 377.2 0.7 4.3e-113 377.0 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KEZ46096.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KEZ46096.1 - 3.1e-05 23.1 0.0 5.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 KEZ46096.1 - 3.7e-05 23.2 0.3 0.0055 16.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KEZ46096.1 - 7.3e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KEZ46096.1 - 0.001 18.9 0.2 1.3 8.7 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 KEZ46096.1 - 0.0027 17.1 0.1 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KEZ46096.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KEZ46096.1 - 0.013 15.8 0.3 0.02 15.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KEZ46096.1 - 0.017 14.5 0.1 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KEZ46096.1 - 0.041 13.8 0.2 0.083 12.8 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KEZ46096.1 - 0.051 12.4 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 KEZ46096.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 KEZ46096.1 - 0.097 11.7 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 KEZ46096.1 - 0.11 12.0 0.0 0.55 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 KEZ46096.1 - 0.12 11.7 0.0 0.41 10.0 0.0 1.9 2 1 0 2 2 2 0 Ras family Guanylate_kin PF00625.16 KEZ46097.1 - 1.9e-61 206.6 0.0 2.3e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KEZ46097.1 - 1.2e-05 25.6 0.0 2.5e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KEZ46097.1 - 1.2e-05 24.5 0.1 0.00013 21.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KEZ46097.1 - 4.3e-05 23.4 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KEZ46097.1 - 0.0004 20.4 0.1 0.0015 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KEZ46097.1 - 0.00071 19.4 0.2 0.0076 16.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KEZ46097.1 - 0.0012 18.9 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ46097.1 - 0.0017 19.1 0.1 0.0031 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEZ46097.1 - 0.0053 16.7 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KEZ46097.1 - 0.0081 15.8 0.3 0.19 11.4 0.2 2.1 1 1 0 1 1 1 1 Archaeal ATPase Thymidylate_kin PF02223.12 KEZ46097.1 - 0.014 14.7 0.0 0.2 11.0 0.0 2.0 1 1 1 2 2 2 0 Thymidylate kinase AAA_14 PF13173.1 KEZ46097.1 - 0.059 13.2 0.0 0.096 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ46097.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain UDPG_MGDP_dh_N PF03721.9 KEZ46097.1 - 0.092 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NACHT PF05729.7 KEZ46097.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_72 PF03198.9 KEZ46098.1 - 1.7e-116 388.6 0.0 2e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KEZ46098.1 - 0.00043 19.5 0.0 0.0099 15.1 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ATP-grasp_2 PF08442.5 KEZ46099.1 - 2.3e-09 36.9 0.0 3.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 KEZ46100.1 - 3.8e-19 68.6 0.0 1.6e-16 60.0 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 KEZ46100.1 - 1.4e-18 67.1 0.1 4.2e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KEZ46100.1 - 2.2e-15 56.5 0.1 4.2e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KEZ46100.1 - 9.1e-06 25.3 0.0 0.00022 20.8 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain MRG PF05712.8 KEZ46101.1 - 1.7e-51 173.9 0.1 2.7e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KEZ46101.1 - 2.4e-08 33.5 0.2 5.1e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KEZ46101.1 - 0.0028 17.2 0.1 0.0063 16.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribonuc_2-5A PF06479.7 KEZ46101.1 - 0.044 13.6 0.1 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease 2-5A DUF3209 PF11483.3 KEZ46101.1 - 0.1 12.9 0.4 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) Methyltransf_23 PF13489.1 KEZ46102.1 - 6.8e-18 64.8 0.0 1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46102.1 - 8.8e-12 45.5 0.0 2e-10 41.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46102.1 - 5.1e-10 39.7 0.0 1.9e-09 37.8 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46102.1 - 7.9e-10 39.1 0.0 1.5e-08 34.9 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46102.1 - 4e-09 36.2 0.0 3.6e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ46102.1 - 4.8e-05 23.6 0.0 0.00031 21.0 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ46102.1 - 0.00014 21.0 0.0 0.0048 16.0 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KEZ46102.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ46102.1 - 0.0023 17.9 0.0 0.018 15.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ46102.1 - 0.0041 16.1 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KEZ46102.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.5 KEZ46102.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.9 KEZ46102.1 - 0.02 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KEZ46102.1 - 0.031 13.3 0.0 0.074 12.1 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KEZ46102.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cnl2_NKP2 PF09447.5 KEZ46103.1 - 1.1e-22 79.4 0.3 1.8e-22 78.7 0.2 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Prefoldin_2 PF01920.15 KEZ46103.1 - 0.0023 17.6 2.0 0.0024 17.6 0.1 1.9 2 1 0 2 2 2 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 KEZ46103.1 - 0.0043 16.9 5.5 0.022 14.6 3.2 2.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2365 PF10157.4 KEZ46103.1 - 0.013 15.4 0.1 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Senescence PF06911.7 KEZ46103.1 - 0.019 14.6 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Senescence-associated protein DUF3829 PF12889.2 KEZ46103.1 - 0.038 13.1 0.9 0.055 12.6 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Sipho_Gp157 PF05565.6 KEZ46103.1 - 0.038 13.5 5.9 0.051 13.1 2.5 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 BRX_N PF13713.1 KEZ46103.1 - 0.085 12.3 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DASH_Dad3 PF08656.5 KEZ46103.1 - 0.14 11.9 0.3 4 7.1 0.0 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad3 Mnd1 PF03962.10 KEZ46103.1 - 0.29 10.7 3.0 0.41 10.2 2.0 1.3 1 0 0 1 1 1 0 Mnd1 family TMCO5 PF14992.1 KEZ46103.1 - 2.2 7.3 7.3 2.2 7.3 0.8 1.8 1 1 1 2 2 2 0 TMCO5 family Ribosomal_60s PF00428.14 KEZ46104.1 - 3.7 8.0 13.0 7.5 7.0 1.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-Q PF13094.1 KEZ46105.1 - 6.7e-18 65.2 0.1 6.7e-18 65.2 0.0 2.8 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Meth_synt_2 PF01717.13 KEZ46106.1 - 1.1e-145 484.7 0.0 1.8e-138 460.9 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KEZ46106.1 - 2.1e-123 411.5 0.3 2.9e-110 368.3 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KEZ46106.1 - 0.0053 15.7 0.0 0.058 12.3 0.0 2.2 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) Prefoldin_2 PF01920.15 KEZ46108.1 - 1.1e-26 92.6 11.1 1.5e-26 92.1 7.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KEZ46108.1 - 0.0085 15.7 2.3 0.0085 15.7 1.6 2.2 1 1 1 2 2 2 1 Prefoldin subunit DUF2019 PF09450.5 KEZ46108.1 - 0.056 13.3 1.8 1.7 8.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) AnfO_nitrog PF09582.5 KEZ46108.1 - 0.057 12.5 0.9 0.099 11.7 0.6 1.4 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) PP_kinase_N PF13089.1 KEZ46108.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Nup54 PF13874.1 KEZ46108.1 - 0.17 11.5 3.3 2.4 7.8 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IFT57 PF10498.4 KEZ46108.1 - 0.31 9.7 11.8 0.74 8.4 8.2 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Vac_Fusion PF02346.11 KEZ46108.1 - 0.94 8.9 3.7 0.44 10.0 0.2 2.0 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Nsp1_C PF05064.8 KEZ46108.1 - 1.4 8.6 8.8 0.66 9.6 0.4 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 KEZ46108.1 - 1.4 8.8 7.6 0.29 11.0 0.6 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_23 PF13476.1 KEZ46108.1 - 2.6 8.3 8.9 3.3 7.9 6.1 1.2 1 0 0 1 1 1 0 AAA domain ACCA PF03255.9 KEZ46108.1 - 2.7 7.5 6.0 2.3 7.7 0.2 2.1 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit NPV_P10 PF05531.7 KEZ46108.1 - 2.8 8.2 6.7 8.4 6.7 0.3 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Adeno_PIX PF03955.9 KEZ46108.1 - 3.8 8.0 5.5 3 8.4 0.1 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Fib_alpha PF08702.5 KEZ46108.1 - 4 7.5 8.0 11 6.1 5.5 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PhoU PF01895.14 KEZ46108.1 - 8 6.9 8.2 8.3 6.9 0.1 2.2 2 0 0 2 2 2 0 PhoU domain DUF148 PF02520.12 KEZ46108.1 - 9.9 5.9 10.4 1.6 8.5 0.6 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF148 CBFD_NFYB_HMF PF00808.18 KEZ46109.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 KEZ46109.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.6 1 1 0 1 1 1 0 Centromere kinetochore component W SseB_C PF14581.1 KEZ46110.1 - 0.15 11.9 2.9 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 SseB protein C-terminal domain DUF1690 PF07956.6 KEZ46110.1 - 0.64 9.9 13.4 1.5 8.8 9.3 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) V_ATPase_I PF01496.14 KEZ46110.1 - 4 5.1 7.2 5.4 4.7 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PDCD9 PF07147.7 KEZ46110.1 - 4.3 6.0 7.7 7.7 5.1 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) Mnd1 PF03962.10 KEZ46110.1 - 8.9 5.9 19.0 0.56 9.8 6.0 2.9 2 1 1 3 3 3 0 Mnd1 family DEAD PF00270.24 KEZ46111.1 - 1.3e-30 106.1 0.0 3.2e-30 104.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KEZ46111.1 - 3.9e-20 71.1 0.0 9e-20 69.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KEZ46111.1 - 7.9e-18 64.0 0.0 1.8e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ46111.1 - 0.046 13.5 1.8 0.088 12.6 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KxDL PF10241.4 KEZ46112.1 - 2.7e-32 110.5 2.1 3.6e-32 110.1 1.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.6 KEZ46112.1 - 0.089 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism Malate_synthase PF01274.17 KEZ46112.1 - 0.12 10.4 1.0 0.14 10.1 0.7 1.0 1 0 0 1 1 1 0 Malate synthase RasGEF PF00617.14 KEZ46113.1 - 9e-52 175.5 0.2 9e-52 175.5 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KEZ46113.1 - 2.5e-12 46.8 0.2 6.6e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Abhydrolase_6 PF12697.2 KEZ46114.1 - 8.2e-07 29.1 0.1 3.7e-06 26.9 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family NACHT PF05729.7 KEZ46114.1 - 1.1e-05 25.1 0.0 3.9e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain WD40 PF00400.27 KEZ46114.1 - 1.2e-05 25.0 0.8 0.0066 16.3 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat AAA_22 PF13401.1 KEZ46114.1 - 0.00024 21.2 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.8 KEZ46114.1 - 0.00096 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEZ46114.1 - 0.0025 17.5 0.0 0.0071 16.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KEZ46114.1 - 0.017 14.3 0.0 0.039 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_19 PF13245.1 KEZ46114.1 - 0.044 13.5 0.0 0.22 11.3 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KEZ46114.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ46114.1 - 0.11 12.6 0.0 1.4 9.1 0.0 2.4 1 1 0 1 1 1 0 RNA helicase AAA PF00004.24 KEZ46115.1 - 5.1e-47 159.3 0.0 2.8e-37 127.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ46115.1 - 1.5e-06 28.3 0.7 0.0027 17.8 0.1 3.9 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KEZ46115.1 - 1.7e-06 28.8 0.0 0.0026 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain CDC48_2 PF02933.12 KEZ46115.1 - 2.4e-06 27.0 0.5 3.7e-05 23.2 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.1 KEZ46115.1 - 1.3e-05 25.4 0.0 0.039 14.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 KEZ46115.1 - 2.7e-05 23.0 0.0 0.003 16.3 0.0 2.5 2 1 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 KEZ46115.1 - 4.7e-05 23.2 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ46115.1 - 0.00011 22.2 0.2 0.0016 18.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KEZ46115.1 - 0.00014 21.8 0.6 0.00035 20.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEZ46115.1 - 0.00055 19.6 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KEZ46115.1 - 0.0007 19.3 1.2 2.5 7.7 0.0 3.5 2 2 1 4 4 4 1 Archaeal ATPase AAA_19 PF13245.1 KEZ46115.1 - 0.0008 19.1 0.4 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KEZ46115.1 - 0.0011 18.8 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain CDC48_N PF02359.13 KEZ46115.1 - 0.0015 18.4 0.0 0.0045 16.9 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KEZ46115.1 - 0.0015 17.5 0.1 0.031 13.3 0.1 2.7 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KEZ46115.1 - 0.0018 17.4 0.0 0.0037 16.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KEZ46115.1 - 0.0032 17.6 0.0 0.037 14.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 KEZ46115.1 - 0.0043 17.3 0.6 0.03 14.6 0.1 2.4 2 0 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.12 KEZ46115.1 - 0.011 15.1 1.4 0.034 13.5 0.0 2.5 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_24 PF13479.1 KEZ46115.1 - 0.017 14.7 0.7 0.056 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 KEZ46115.1 - 0.04 13.5 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 KEZ46115.1 - 0.04 12.8 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.1 KEZ46115.1 - 0.043 13.2 1.5 0.64 9.3 0.0 3.0 2 2 1 3 3 3 0 AAA domain AAA_28 PF13521.1 KEZ46115.1 - 0.048 13.6 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KEZ46115.1 - 0.073 12.7 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 KEZ46115.1 - 0.073 12.0 0.0 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KEZ46115.1 - 0.087 11.9 0.1 0.6 9.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin KaiC PF06745.8 KEZ46115.1 - 0.087 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 KaiC SKI PF01202.17 KEZ46115.1 - 0.11 12.3 0.1 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 KEZ46115.1 - 0.16 11.1 0.0 0.4 9.8 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 KEZ46115.1 - 0.18 10.6 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KEZ46115.1 - 0.31 10.6 5.6 7.6 6.1 0.0 3.9 5 0 0 5 5 4 0 NACHT domain RNase_PH PF01138.16 KEZ46116.1 - 5.1e-16 59.1 0.0 1.1e-15 58.0 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KEZ46116.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Cir_N PF10197.4 KEZ46117.1 - 0.00038 20.4 1.8 0.00038 20.4 1.2 4.4 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2796 PF10986.3 KEZ46117.1 - 5.3 6.9 9.3 0.35 10.8 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2796) Cytochrom_C PF00034.16 KEZ46118.1 - 1.2e-10 42.0 0.0 1.9e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KEZ46118.1 - 7.5e-09 35.6 3.4 4.3e-08 33.1 2.3 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KEZ46118.1 - 0.0034 16.8 2.3 0.018 14.5 1.6 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 KEZ46118.1 - 0.064 12.9 0.1 0.08 12.5 0.1 1.4 1 1 0 1 1 1 0 Cytochrome C1 family CCP_MauG PF03150.9 KEZ46118.1 - 0.081 13.2 0.1 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.4 KEZ46118.1 - 0.15 11.3 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Snf7 PF03357.16 KEZ46120.1 - 2.4e-33 114.9 7.2 2.8e-33 114.6 5.0 1.0 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 KEZ46120.1 - 0.0037 16.7 0.2 0.0079 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) DUF2138 PF09909.4 KEZ46120.1 - 0.052 11.6 0.2 0.095 10.8 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) PMSR PF01625.16 KEZ46120.1 - 0.13 12.1 0.4 6.1 6.6 0.0 2.3 1 1 1 2 2 2 0 Peptide methionine sulfoxide reductase Fructosamin_kin PF03881.9 KEZ46121.1 - 3.1e-64 216.7 0.0 3.2e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KEZ46121.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glu_synthase PF01645.12 KEZ46122.1 - 2.3e-158 526.9 0.0 3.3e-158 526.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KEZ46122.1 - 3.4e-140 466.8 0.0 4.6e-140 466.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KEZ46122.1 - 1.3e-116 388.8 0.0 2.1e-116 388.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KEZ46122.1 - 5.5e-66 221.4 0.7 1.1e-65 220.4 0.5 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KEZ46122.1 - 3.2e-22 78.2 0.0 7.5e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KEZ46122.1 - 4.5e-14 52.8 0.0 1.7e-13 50.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ46122.1 - 6.9e-10 39.3 0.0 0.00065 19.8 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ46122.1 - 2.4e-09 37.0 0.1 9.9e-09 35.1 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ46122.1 - 2.1e-07 31.2 0.0 5.3e-05 23.5 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ46122.1 - 2.4e-07 30.1 0.0 4.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KEZ46122.1 - 4.3e-06 25.8 0.0 1.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KEZ46122.1 - 3.6e-05 22.4 0.6 5.7e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein FMO-like PF00743.14 KEZ46122.1 - 9.9e-05 20.7 0.1 0.29 9.2 0.0 2.5 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.1 KEZ46122.1 - 0.00028 21.0 0.0 1.8 8.8 0.0 3.2 3 0 0 3 3 3 2 Putative NAD(P)-binding Thi4 PF01946.12 KEZ46122.1 - 0.0009 18.3 0.0 0.0023 17.0 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KEZ46122.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ46122.1 - 0.0015 17.4 0.4 0.0059 15.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KEZ46122.1 - 0.0039 16.2 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KEZ46122.1 - 0.0099 15.6 0.0 0.029 14.0 0.0 1.8 2 0 0 2 2 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 KEZ46122.1 - 0.011 15.6 0.6 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_9 PF13454.1 KEZ46122.1 - 0.032 14.0 0.0 0.13 11.9 0.0 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding GATase_6 PF13522.1 KEZ46122.1 - 0.072 13.0 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 Glutamine amidotransferase domain F420_oxidored PF03807.12 KEZ46122.1 - 0.11 12.9 0.0 0.86 10.0 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 KEZ46122.1 - 0.14 11.6 0.1 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Relaxase PF03432.9 KEZ46122.1 - 0.17 11.2 2.8 0.34 10.2 1.9 1.4 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Shikimate_DH PF01488.15 KEZ46122.1 - 0.21 11.6 0.4 14 5.8 0.1 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 KEZ46122.1 - 0.33 9.8 0.0 22 3.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Apc15p PF05841.6 KEZ46123.1 - 3.6e-21 76.1 2.9 3.6e-21 76.1 2.0 2.1 2 0 0 2 2 2 1 Apc15p protein Raftlin PF15250.1 KEZ46123.1 - 0.33 9.4 2.0 0.48 8.8 1.4 1.2 1 0 0 1 1 1 0 Raftlin SNARE PF05739.14 KEZ46124.1 - 4.8e-09 35.7 1.8 6.6e-09 35.3 1.2 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KEZ46124.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 CHZ PF09649.5 KEZ46125.1 - 1.2e-17 62.8 5.5 1.2e-17 62.8 3.8 3.0 3 2 0 3 3 3 1 Histone chaperone domain CHZ NCKAP5 PF15246.1 KEZ46125.1 - 0.079 12.3 0.9 0.11 11.9 0.6 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein YtxH PF12732.2 KEZ46125.1 - 0.91 9.9 0.0 0.91 9.9 0.0 2.3 2 1 0 2 2 2 0 YtxH-like protein DUF2072 PF09845.4 KEZ46125.1 - 1.3 8.9 6.2 2 8.3 4.3 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) TFIIA PF03153.8 KEZ46125.1 - 4.4 7.0 24.1 6 6.6 16.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRTase_1 PF11202.3 KEZ46126.1 - 0.16 10.9 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) Cyclin PF08613.6 KEZ46127.1 - 4.8e-29 101.6 0.0 9e-29 100.8 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KEZ46127.1 - 0.00025 20.6 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 KEZ46128.1 - 3.6e-13 48.8 11.3 8.8e-05 22.1 0.0 9.7 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KEZ46128.1 - 1.7e-09 37.8 6.4 0.02 15.3 0.0 7.3 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.1 KEZ46128.1 - 1.8e-07 31.2 13.4 0.033 14.4 0.0 6.1 7 1 0 7 7 7 2 HEAT repeats HEAT PF02985.17 KEZ46128.1 - 2.2e-07 30.3 17.0 0.22 11.6 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat V-ATPase_H_N PF03224.9 KEZ46128.1 - 2.2e-06 27.0 0.0 0.0012 18.0 0.0 3.6 3 1 0 3 3 3 1 V-ATPase subunit H Cnd1 PF12717.2 KEZ46128.1 - 0.38 10.5 2.7 10 5.9 0.0 3.8 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Velvet PF11754.3 KEZ46129.1 - 1.2e-64 217.7 0.0 1.9e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Velvet factor TIG PF01833.19 KEZ46130.1 - 8.7e-13 48.0 0.4 8.7e-13 48.0 0.3 2.0 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.25 KEZ46130.1 - 1.3e-12 46.8 0.3 1.5e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KEZ46130.1 - 1.8e-12 47.0 0.1 1.8e-11 43.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEZ46130.1 - 1.2e-11 44.7 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ46130.1 - 2.2e-07 30.4 0.2 0.00051 20.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KEZ46130.1 - 1.2e-06 28.7 0.1 7.8e-06 26.2 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF4118 PF13493.1 KEZ46130.1 - 6.7e-05 23.0 0.2 0.00012 22.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) zf-C4_ClpX PF06689.8 KEZ46130.1 - 0.3 10.6 0.1 0.61 9.6 0.1 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger Cauli_VI PF01693.11 KEZ46131.1 - 8.7e-33 112.0 8.6 2.4e-18 65.8 0.1 2.8 3 0 0 3 3 3 2 Caulimovirus viroplasmin RNase_H PF00075.19 KEZ46131.1 - 4.1e-27 95.1 0.4 6.5e-27 94.4 0.3 1.3 1 0 0 1 1 1 1 RNase H dCMP_cyt_deam_1 PF00383.17 KEZ46132.1 - 1.8e-09 37.1 0.0 3.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 6PF2K PF01591.13 KEZ46133.1 - 1.3e-66 223.8 0.0 2.2e-47 161.0 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KEZ46133.1 - 1.2e-25 90.4 0.1 8e-25 87.7 0.0 2.3 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KEZ46133.1 - 1.7e-07 31.1 0.0 7.3e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEZ46133.1 - 0.0021 17.1 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin KTI12 PF08433.5 KEZ46133.1 - 0.052 12.7 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 KEZ46133.1 - 0.058 14.2 0.3 0.42 11.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KEZ46134.1 - 3.9e-08 33.0 9.5 6.1e-08 32.4 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEZ46134.1 - 0.00014 20.6 0.5 0.00022 19.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MDFI PF15316.1 KEZ46134.1 - 0.0064 16.4 0.8 0.011 15.7 0.6 1.3 1 0 0 1 1 1 1 MyoD family inhibitor zf-RING_2 PF13639.1 KEZ46135.1 - 9.2e-15 54.1 3.9 1.5e-14 53.5 2.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEZ46135.1 - 5.7e-08 32.7 1.9 1e-07 31.9 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KEZ46135.1 - 1.5e-07 30.9 2.6 2.5e-07 30.2 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ46135.1 - 2.9e-06 27.1 4.4 5e-06 26.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ46135.1 - 1.1e-05 25.0 1.6 1.7e-05 24.4 1.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KEZ46135.1 - 5.5e-05 22.7 2.0 9.6e-05 21.9 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KEZ46135.1 - 0.0018 18.0 1.2 0.0034 17.1 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KEZ46135.1 - 0.053 13.1 2.4 0.093 12.3 1.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 KEZ46135.1 - 0.073 13.2 0.1 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KEZ46135.1 - 0.085 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 KEZ46135.1 - 0.18 11.8 2.5 0.3 11.1 1.7 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 KEZ46135.1 - 0.54 10.2 3.7 2.7 8.0 2.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 KEZ46135.1 - 0.98 9.1 3.0 2.1 8.0 2.0 1.6 1 1 0 1 1 1 0 PHD-finger Lyase_1 PF00206.15 KEZ46136.1 - 1.3e-16 60.7 0.4 2.3e-16 59.9 0.1 1.5 1 1 1 2 2 2 1 Lyase ADSL_C PF10397.4 KEZ46136.1 - 4.5e-13 49.0 0.0 1.2e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus CAP_GLY PF01302.20 KEZ46137.1 - 5e-22 77.3 1.8 7.2e-22 76.8 1.2 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KEZ46137.1 - 2.6e-19 69.2 0.0 4.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KEZ46137.1 - 3.1e-06 26.4 0.0 6.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family MFS_1 PF07690.11 KEZ46138.1 - 3.2e-18 65.5 16.9 3.2e-18 65.5 11.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily VHS PF00790.14 KEZ46139.1 - 3.3e-07 30.0 0.0 7.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain zf-C2HC_2 PF13913.1 KEZ46139.1 - 0.1 12.2 3.9 1 9.1 0.5 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 KEZ46139.1 - 0.17 12.2 0.9 19 5.8 0.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger GFO_IDH_MocA PF01408.17 KEZ46140.1 - 3.1e-16 59.9 0.1 5.6e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Myb_DNA-binding PF00249.26 KEZ46141.1 - 6.9e-10 38.8 0.2 2.2e-09 37.2 0.1 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEZ46141.1 - 3.5e-06 27.0 0.6 7.6e-06 25.9 0.3 1.7 1 1 1 2 2 2 1 Myb-like DNA-binding domain MCPVI PF02993.9 KEZ46141.1 - 0.21 11.6 6.4 0.32 11.1 4.4 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Totivirus_coat PF05518.6 KEZ46141.1 - 4.2 5.0 13.8 5.6 4.6 9.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein ABC2_membrane PF01061.19 KEZ46142.1 - 5.6e-90 300.1 64.8 3.6e-46 156.9 13.8 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KEZ46142.1 - 7.2e-39 131.6 1.0 2.6e-30 104.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KEZ46142.1 - 4.1e-38 130.7 0.0 2e-18 67.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KEZ46142.1 - 3.2e-16 59.1 0.0 8.1e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KEZ46142.1 - 2e-07 30.5 0.0 0.0012 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KEZ46142.1 - 9.8e-06 25.5 0.1 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KEZ46142.1 - 3.2e-05 23.1 0.1 0.0043 16.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ46142.1 - 8.9e-05 23.2 0.0 0.009 16.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KEZ46142.1 - 0.00032 20.1 0.5 0.0078 15.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KEZ46142.1 - 0.00037 20.5 0.4 0.0053 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KEZ46142.1 - 0.0018 18.5 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KEZ46142.1 - 0.0019 17.6 0.8 0.039 13.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KEZ46142.1 - 0.004 16.8 0.8 1.3 8.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 KEZ46142.1 - 0.004 16.4 0.0 1.5 8.0 0.0 3.3 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KEZ46142.1 - 0.0091 16.1 0.0 0.69 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ46142.1 - 0.013 15.2 0.2 6.3 6.6 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KEZ46142.1 - 0.051 13.7 0.0 9.4 6.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEZ46142.1 - 0.061 13.4 0.1 11 6.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 KEZ46142.1 - 0.071 12.5 1.1 4.1 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_21 PF13304.1 KEZ46142.1 - 0.072 13.0 0.0 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 KEZ46142.1 - 0.088 13.3 0.1 24 5.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 KEZ46142.1 - 0.12 11.8 0.1 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 KEZ46142.1 - 0.15 11.0 61.3 0.31 10.0 21.5 4.1 2 2 1 3 3 3 0 ABC-2 family transporter protein MMR_HSR1 PF01926.18 KEZ46142.1 - 0.17 11.8 0.0 18 5.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3043 PF11241.3 KEZ46142.1 - 1.6 8.2 5.3 1.9 8.0 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) UPF0079 PF02367.12 KEZ46142.1 - 1.8 8.2 6.7 1.6 8.3 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 PCI PF01399.22 KEZ46143.1 - 2.3e-19 69.6 1.6 7.4e-19 68.0 0.1 2.5 3 1 0 3 3 2 1 PCI domain TPR_7 PF13176.1 KEZ46143.1 - 8.8e-06 25.1 2.9 0.39 10.6 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46143.1 - 2.6e-05 23.6 1.4 7.7 6.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46143.1 - 0.00011 22.7 13.4 0.22 12.2 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46143.1 - 0.0016 18.2 6.7 24 5.1 0.0 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat DDRGK PF09756.4 KEZ46143.1 - 0.003 16.9 0.2 0.003 16.9 0.1 1.9 2 0 0 2 2 2 1 DDRGK domain TPR_14 PF13428.1 KEZ46143.1 - 0.0056 17.1 10.8 1 10.2 0.0 5.9 5 2 1 6 6 6 1 Tetratricopeptide repeat Med2 PF11214.3 KEZ46143.1 - 0.042 13.8 0.2 0.042 13.8 0.1 2.8 3 1 0 3 3 3 0 Mediator complex subunit 2 TPR_11 PF13414.1 KEZ46143.1 - 0.045 13.4 8.3 0.49 10.0 0.0 3.9 3 1 0 4 4 4 0 TPR repeat TPR_19 PF14559.1 KEZ46143.1 - 0.047 14.0 0.2 0.047 14.0 0.1 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ46143.1 - 0.18 12.3 2.2 0.94 10.0 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46143.1 - 0.23 11.1 7.8 8.5 6.1 0.0 5.6 6 1 1 7 7 7 0 Tetratricopeptide repeat YfdX PF10938.3 KEZ46143.1 - 0.67 9.6 7.3 0.31 10.6 0.1 3.3 3 1 0 3 3 3 0 YfdX protein Mito_carr PF00153.22 KEZ46144.1 - 3e-54 180.6 5.4 3.8e-18 64.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 KEZ46144.1 - 0.0016 18.1 0.2 0.0068 16.1 0.2 2.1 2 0 0 2 2 2 1 UcrQ family HMD PF03201.11 KEZ46144.1 - 0.039 13.8 0.0 18 5.3 0.0 3.0 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Mak10 PF04112.8 KEZ46145.1 - 1.2e-23 83.1 0.2 1.1e-20 73.5 0.0 3.3 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 KEZ46146.1 - 1.9e-22 78.5 3.2 1.9e-22 78.5 2.2 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain DUF2184 PF09950.4 KEZ46146.1 - 0.038 13.0 0.3 0.039 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) RGS PF00615.14 KEZ46147.1 - 0.099 12.7 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Regulator of G protein signaling domain tRNA-synt_2b PF00587.20 KEZ46148.1 - 1.3e-63 213.6 0.0 1.9e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KEZ46148.1 - 3.8e-21 74.8 0.0 1e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain RRS1 PF04939.7 KEZ46148.1 - 0.085 12.3 0.4 0.18 11.2 0.3 1.5 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) Glyco_hydro_72 PF03198.9 KEZ46149.1 - 5.5e-76 255.5 0.6 2e-62 211.0 0.2 2.2 1 1 1 2 2 2 2 Glucanosyltransferase adh_short PF00106.20 KEZ46151.1 - 7.4e-28 97.5 2.4 1.1e-27 97.0 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ46151.1 - 3e-12 46.8 0.0 4.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ46151.1 - 2.8e-11 43.3 4.7 1.7e-10 40.8 3.3 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KEZ46151.1 - 0.0012 18.3 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KEZ46151.1 - 0.0027 17.7 0.3 0.0091 16.0 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding HI0933_like PF03486.9 KEZ46151.1 - 0.063 11.7 0.1 0.086 11.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein WD40 PF00400.27 KEZ46152.1 - 8.9e-36 120.4 19.8 1e-08 34.7 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KEZ46152.1 - 5.9e-30 103.1 13.1 1.1e-29 102.3 9.1 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 KEZ46152.1 - 0.0012 18.6 0.1 0.016 14.8 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RNA_pol_A_bac PF01000.21 KEZ46153.1 - 2.2e-32 111.4 0.0 4.6e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KEZ46153.1 - 6.2e-13 47.6 0.0 8e-13 47.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HET PF06985.6 KEZ46154.1 - 1.2e-17 64.4 0.0 6.1e-17 62.0 0.0 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HeLo PF14479.1 KEZ46154.1 - 4.4e-16 59.2 0.0 7.2e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Cyt-b5 PF00173.23 KEZ46154.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain 4F5 PF04419.9 KEZ46155.1 - 2.9e-07 31.0 7.3 2.9e-07 31.0 5.1 3.3 3 1 1 4 4 4 1 4F5 protein family SMN PF06003.7 KEZ46157.1 - 0.11 11.5 6.3 0.21 10.6 0.7 2.5 1 1 0 2 2 2 0 Survival motor neuron protein (SMN) RRM_1 PF00076.17 KEZ46158.1 - 1.6e-15 56.5 0.0 1.6e-15 56.5 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ46158.1 - 3.7e-11 42.8 0.0 1.2e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ46158.1 - 4.3e-09 36.0 0.3 1.3e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ46158.1 - 0.091 12.5 0.1 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GRAB PF10375.4 KEZ46159.1 - 2.1e-08 33.4 0.1 4.2e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain IncA PF04156.9 KEZ46159.1 - 2.8e-05 23.8 59.1 0.037 13.6 10.7 3.2 1 1 1 3 3 3 3 IncA protein Myosin_tail_1 PF01576.14 KEZ46159.1 - 4.1e-05 21.5 58.1 5.4e-05 21.1 40.3 1.1 1 0 0 1 1 1 1 Myosin tail DUF3584 PF12128.3 KEZ46159.1 - 0.00036 18.0 45.3 0.00049 17.5 31.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Mitofilin PF09731.4 KEZ46159.1 - 0.0012 17.5 34.9 0.0012 17.5 24.2 2.1 1 1 1 2 2 2 1 Mitochondrial inner membrane protein Rootletin PF15035.1 KEZ46159.1 - 0.0046 16.9 49.7 0.086 12.8 9.1 3.2 2 1 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 KEZ46159.1 - 0.005 16.6 63.4 0.1 12.4 21.9 3.8 2 2 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 KEZ46159.1 - 0.0062 16.3 1.9 0.0062 16.3 1.3 3.5 1 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KEZ46159.1 - 0.016 15.4 26.4 0.019 15.2 1.3 4.7 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 KEZ46159.1 - 0.021 14.3 53.4 0.093 12.1 12.3 3.1 1 1 1 3 3 3 0 Intermediate filament protein DUF1664 PF07889.7 KEZ46159.1 - 0.024 14.4 28.8 0.22 11.3 3.5 4.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) FH2 PF02181.18 KEZ46159.1 - 0.031 13.1 36.8 0.03 13.2 4.4 3.3 1 1 2 3 3 3 0 Formin Homology 2 Domain Spc7 PF08317.6 KEZ46159.1 - 0.1 11.2 49.2 1.3 7.5 12.7 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2580 PF10824.3 KEZ46159.1 - 0.1 12.9 12.2 0.13 12.6 2.4 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2580) Phage_GP20 PF06810.6 KEZ46159.1 - 0.11 11.9 46.0 0.16 11.3 6.9 3.5 1 1 2 3 3 3 0 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 KEZ46159.1 - 0.13 11.4 17.2 1.1 8.3 2.9 2.9 1 1 3 4 4 4 0 Reovirus sigma C capsid protein APG6 PF04111.7 KEZ46159.1 - 0.13 11.2 55.6 0.2 10.6 10.5 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 BicD PF09730.4 KEZ46159.1 - 0.17 10.1 50.8 0.15 10.3 14.7 3.0 1 1 2 3 3 3 0 Microtubule-associated protein Bicaudal-D BLOC1_2 PF10046.4 KEZ46159.1 - 0.38 10.9 34.7 2.4 8.3 1.4 4.5 1 1 5 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 KEZ46159.1 - 0.43 10.3 59.8 0.15 11.7 19.7 3.5 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 KEZ46159.1 - 0.56 9.6 19.2 0.61 9.4 1.4 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain TBPIP PF07106.8 KEZ46159.1 - 0.66 9.4 46.8 0.89 9.0 8.3 4.4 1 1 3 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ERM PF00769.14 KEZ46159.1 - 0.69 9.4 66.3 0.046 13.2 20.1 3.8 1 1 2 3 3 3 0 Ezrin/radixin/moesin family EzrA PF06160.7 KEZ46159.1 - 0.72 7.9 45.9 0.57 8.2 14.0 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF812 PF05667.6 KEZ46159.1 - 0.8 8.1 49.9 1.1 7.7 5.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) AAA_27 PF13514.1 KEZ46159.1 - 1 6.9 51.7 2.2 5.8 35.9 1.5 1 1 0 1 1 1 0 AAA domain TMPIT PF07851.8 KEZ46159.1 - 1.3 8.0 32.4 0.49 9.4 7.4 2.9 1 1 1 3 3 3 0 TMPIT-like protein Fib_alpha PF08702.5 KEZ46159.1 - 2.5 8.2 29.9 4.6 7.3 7.6 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family NYD-SP28_assoc PF14775.1 KEZ46159.1 - 2.8 7.7 17.2 0.22 11.2 2.8 3.4 3 0 0 3 3 2 0 Sperm tail C-terminal domain GAS PF13851.1 KEZ46159.1 - 3 7.0 54.7 2 7.5 9.8 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding FUSC PF04632.7 KEZ46159.1 - 4.7 5.5 25.2 0.37 9.1 6.6 2.2 1 1 0 2 2 2 0 Fusaric acid resistance protein family FlaC_arch PF05377.6 KEZ46159.1 - 7.2 6.5 36.1 15 5.5 0.1 7.2 2 2 4 7 7 7 0 Flagella accessory protein C (FlaC) Hemagglutinin PF00509.13 KEZ46159.1 - 7.4 4.5 12.7 0.64 8.0 1.0 2.4 2 1 0 2 2 2 0 Haemagglutinin DUF4618 PF15397.1 KEZ46159.1 - 9.2 5.5 43.0 1.1 8.5 6.1 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) CotH PF08757.6 KEZ46160.1 - 0.09 11.9 0.5 0.12 11.5 0.3 1.1 1 0 0 1 1 1 0 CotH protein CHD5 PF04420.9 KEZ46161.1 - 1e-54 184.5 1.6 1.2e-54 184.2 1.1 1.1 1 0 0 1 1 1 1 CHD5-like protein Rab5-bind PF09311.6 KEZ46161.1 - 0.014 15.3 1.7 0.019 14.8 1.2 1.1 1 0 0 1 1 1 0 Rabaptin-like protein FbpA PF05833.6 KEZ46161.1 - 0.02 13.4 1.1 0.025 13.1 0.7 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PcfJ PF14284.1 KEZ46161.1 - 0.09 12.2 0.5 0.13 11.7 0.4 1.1 1 0 0 1 1 1 0 PcfJ-like protein FtsL PF04999.8 KEZ46161.1 - 0.14 11.9 1.7 0.27 10.9 0.7 2.0 1 1 0 1 1 1 0 Cell division protein FtsL TMEM247 PF15444.1 KEZ46161.1 - 0.15 11.8 0.4 0.21 11.3 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DUF2681 PF10883.3 KEZ46161.1 - 6.2 7.1 6.8 33 4.7 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Asp PF00026.18 KEZ46162.1 - 3.1e-69 233.6 1.6 3.9e-69 233.3 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ46162.1 - 2.5e-10 40.5 0.2 5.3e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KEZ46162.1 - 6.1e-06 26.6 0.1 0.0068 16.8 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KEZ46162.1 - 0.041 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Aa_trans PF01490.13 KEZ46163.1 - 2.9e-73 246.7 26.1 3.5e-73 246.4 18.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HlyIII PF03006.15 KEZ46163.1 - 8 5.8 17.1 0.044 13.1 1.7 2.5 1 1 1 2 2 2 0 Haemolysin-III related Ras PF00071.17 KEZ46164.1 - 4.8e-55 185.3 0.0 5.5e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ46164.1 - 1e-15 58.2 0.0 1.5e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ46164.1 - 1.5e-07 30.7 0.0 2.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KEZ46164.1 - 0.0014 17.8 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KEZ46164.1 - 0.044 12.9 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Syntaxin-6_N PF09177.6 KEZ46165.1 - 0.015 15.7 5.1 0.056 13.8 0.1 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal KOW PF00467.24 KEZ46165.1 - 0.094 12.4 0.5 0.19 11.4 0.3 1.6 1 0 0 1 1 1 0 KOW motif IKI3 PF04762.7 KEZ46166.1 - 0 1017.2 0.0 0 1015.9 0.0 1.6 1 1 0 1 1 1 1 IKI3 family TPR_8 PF13181.1 KEZ46166.1 - 0.086 12.6 2.6 0.19 11.6 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46166.1 - 0.086 12.4 1.4 0.56 9.9 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HIRA_B PF09453.5 KEZ46166.1 - 1 8.9 3.3 11 5.7 0.1 2.5 2 0 0 2 2 2 0 HIRA B motif TPR_12 PF13424.1 KEZ46166.1 - 2.4 8.1 7.4 4.5 7.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Hpt PF01627.18 KEZ46167.1 - 9.7e-12 44.7 0.0 4.1e-11 42.7 0.0 2.1 1 1 1 2 2 2 1 Hpt domain DUF4564 PF15169.1 KEZ46167.1 - 0.14 11.9 5.5 0.13 12.0 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) RNase_H2-Ydr279 PF09468.5 KEZ46167.1 - 0.16 11.1 3.3 0.19 10.8 2.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Sporozoite_P67 PF05642.6 KEZ46167.1 - 0.46 8.2 8.9 0.57 7.9 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RP-C_C PF11800.3 KEZ46167.1 - 0.61 9.7 6.6 0.66 9.6 3.8 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region CDC45 PF02724.9 KEZ46167.1 - 1.3 7.0 15.4 1.7 6.6 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KEZ46167.1 - 1.9 6.2 18.6 2 6.2 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 KEZ46167.1 - 2.1 8.1 7.8 4.6 7.0 5.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Hid1 PF12722.2 KEZ46167.1 - 3.5 5.1 4.5 4.8 4.7 3.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.7 KEZ46167.1 - 4.2 6.5 10.0 5.6 6.1 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein eIF-3c_N PF05470.7 KEZ46167.1 - 6.7 4.6 11.7 11 3.9 8.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Paf1 PF03985.8 KEZ46167.1 - 9.1 4.8 17.4 3.8 6.1 10.2 1.6 2 0 0 2 2 2 0 Paf1 DUF2201_N PF13203.1 KEZ46167.1 - 9.2 5.3 10.8 11 5.0 7.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain MscS_porin PF12795.2 KEZ46168.1 - 0.0041 16.4 4.5 0.0041 16.4 3.1 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Spc7 PF08317.6 KEZ46168.1 - 0.014 14.0 4.3 0.026 13.1 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Sec2p PF06428.6 KEZ46168.1 - 0.075 12.8 5.9 0.34 10.7 0.0 3.3 2 1 0 3 3 3 0 GDP/GTP exchange factor Sec2p Prominin PF05478.6 KEZ46168.1 - 0.14 9.6 0.7 0.21 9.0 0.5 1.2 1 0 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.3 KEZ46168.1 - 0.18 11.6 10.0 3.8 7.3 0.1 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.1 KEZ46168.1 - 0.39 10.1 9.2 3.9 6.8 1.5 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.4 KEZ46168.1 - 3.4 6.5 8.4 0.4 9.5 2.7 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 KEZ46168.1 - 5.3 5.3 7.8 6.9 4.9 0.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family IncA PF04156.9 KEZ46168.1 - 6.3 6.3 10.2 36 3.8 7.1 2.0 1 1 0 1 1 1 0 IncA protein HSP70 PF00012.15 KEZ46169.1 - 3.7e-09 35.0 0.1 3.1e-08 32.0 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein Pkinase PF00069.20 KEZ46170.1 - 1.7e-60 204.3 0.0 2.4e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46170.1 - 8.1e-32 110.2 0.0 2.7e-30 105.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KEZ46170.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.2 KEZ46171.1 - 7.9e-16 57.8 2.0 8.8e-16 57.7 0.2 1.9 2 0 0 2 2 2 1 Stc1 domain BCDHK_Adom3 PF10436.4 KEZ46172.1 - 3.3e-67 225.1 0.0 5e-67 224.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KEZ46172.1 - 3.4e-17 62.1 0.0 9.8e-17 60.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KEZ46172.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Apolipoprotein PF01442.13 KEZ46173.1 - 0.049 13.1 6.0 0.1 12.1 4.2 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.4 KEZ46173.1 - 0.1 12.4 6.4 0.048 13.5 2.5 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 KEZ46173.1 - 0.79 8.3 7.8 3.8 6.0 3.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 KEZ46173.1 - 0.81 9.9 3.8 44 4.4 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Sugar_tr PF00083.19 KEZ46174.1 - 1.9e-80 270.6 19.4 2.8e-80 270.1 13.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ46174.1 - 8.6e-12 44.4 26.1 8.6e-12 44.4 18.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyridoxal_deC PF00282.14 KEZ46176.1 - 2.1e-17 62.6 0.0 3.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KEZ46176.1 - 9.9e-05 21.2 0.0 0.00017 20.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KEZ46176.1 - 0.0039 16.2 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Resolvase PF00239.16 KEZ46176.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain Glyco_transf_34 PF05637.7 KEZ46177.1 - 4.8e-68 229.2 0.0 5.8e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KEZ46177.1 - 0.029 13.6 0.3 1.9 7.7 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function, DUF273 Proteasome PF00227.21 KEZ46178.1 - 2.6e-57 193.1 0.0 1.7e-33 115.5 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KEZ46178.1 - 2.4e-11 42.7 0.2 5.7e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 KEZ46178.1 - 0.1 11.0 0.3 7 5.0 0.0 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RCC1_2 PF13540.1 KEZ46179.1 - 3.2e-16 58.4 5.1 1.3e-05 24.7 0.2 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 KEZ46179.1 - 1.6e-05 25.0 4.9 0.007 16.5 0.1 5.0 5 2 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ribonuclease_3 PF00636.21 KEZ46180.1 - 4.3e-38 130.2 0.0 6e-18 65.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KEZ46180.1 - 1.6e-20 73.3 0.0 9e-08 32.1 0.0 3.8 3 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 KEZ46180.1 - 1.6e-15 56.7 0.0 5.1e-15 55.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KEZ46180.1 - 1.8e-15 56.4 0.0 4.9e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 KEZ46180.1 - 1.3e-10 40.9 0.1 5.1e-06 26.0 0.0 2.7 1 1 1 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KEZ46180.1 - 9.4e-07 28.8 0.0 0.00053 19.8 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 KEZ46180.1 - 0.0013 18.1 0.1 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 dsrm PF00035.20 KEZ46180.1 - 0.025 15.1 0.0 2.2 8.9 0.0 2.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF2075 PF09848.4 KEZ46180.1 - 0.026 13.4 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zot PF05707.7 KEZ46180.1 - 0.059 12.8 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SecA_DEAD PF07517.9 KEZ46180.1 - 0.067 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Rgp1 PF08737.5 KEZ46181.1 - 5.5e-117 391.3 0.0 3.1e-116 388.8 0.0 2.0 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 KEZ46181.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain tRNA-synt_2d PF01409.15 KEZ46182.1 - 1.4e-48 165.2 0.3 4.4e-25 88.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KEZ46182.1 - 2.2e-26 91.8 0.0 6.8e-26 90.2 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 KEZ46182.1 - 0.015 14.0 0.2 0.043 12.5 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) AAA_21 PF13304.1 KEZ46182.1 - 0.14 12.1 0.0 0.95 9.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.22 KEZ46183.1 - 2.3e-45 152.2 9.2 5e-17 61.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Clathrin PF00637.15 KEZ46184.1 - 1.8e-23 82.7 4.1 7e-22 77.5 1.8 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 KEZ46184.1 - 1.2e-20 73.1 0.1 3e-20 71.8 0.1 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 KEZ46184.1 - 0.00018 21.1 3.6 0.00037 20.1 2.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_19 PF14559.1 KEZ46184.1 - 0.00075 19.7 4.9 0.8 10.0 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-RING_2 PF13639.1 KEZ46184.1 - 0.0016 18.2 4.7 0.0041 16.9 3.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KEZ46184.1 - 0.03 13.9 2.4 0.085 12.5 1.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KEZ46184.1 - 0.039 14.0 1.7 0.088 12.9 1.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_11 PF13414.1 KEZ46184.1 - 0.042 13.4 0.2 0.88 9.2 0.0 2.9 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 KEZ46184.1 - 0.11 13.1 2.1 28 5.7 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 KEZ46184.1 - 0.12 12.1 1.2 0.29 10.9 0.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_8 PF13181.1 KEZ46184.1 - 0.2 11.4 1.8 12 5.9 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 KEZ46184.1 - 0.21 11.6 8.0 0.2 11.7 2.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Curto_V2 PF07325.6 KEZ46184.1 - 0.31 10.6 1.5 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Curtovirus V2 protein zf-Apc11 PF12861.2 KEZ46184.1 - 0.32 10.8 1.4 0.86 9.4 1.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_16 PF13432.1 KEZ46184.1 - 5.6 7.7 9.4 3.7 8.3 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Na_Ca_ex PF01699.19 KEZ46185.1 - 2.7e-30 104.7 29.8 4.4e-18 65.2 3.1 3.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KEZ46185.1 - 5.1e-15 55.6 14.0 5.1e-15 55.6 9.7 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF307) AAA PF00004.24 KEZ46186.1 - 5.1e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ46186.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KEZ46186.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KEZ46186.1 - 3.4e-06 27.1 0.0 1.1e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KEZ46186.1 - 4.7e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ46186.1 - 5.9e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEZ46186.1 - 7.7e-05 21.8 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KEZ46186.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KEZ46186.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KEZ46186.1 - 0.00091 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KEZ46186.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KEZ46186.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KEZ46186.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 KEZ46186.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KEZ46186.1 - 0.0038 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KEZ46186.1 - 0.0062 16.8 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEZ46186.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KEZ46186.1 - 0.0089 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 KaiC DUF815 PF05673.8 KEZ46186.1 - 0.017 14.0 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KEZ46186.1 - 0.017 14.5 0.1 0.085 12.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 KEZ46186.1 - 0.018 14.2 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 KEZ46186.1 - 0.019 14.4 0.0 0.086 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KEZ46186.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ46186.1 - 0.029 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 KEZ46186.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 KEZ46186.1 - 0.048 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KEZ46186.1 - 0.05 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KEZ46186.1 - 0.079 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 KEZ46186.1 - 0.1 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF2072 PF09845.4 KEZ46186.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Y_phosphatase PF00102.22 KEZ46187.1 - 3.6e-58 196.6 0.0 1.7e-31 109.3 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 KEZ46187.1 - 4.5e-12 46.3 0.0 2.7e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 KEZ46187.1 - 0.029 13.9 0.3 0.068 12.7 0.2 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KEZ46187.1 - 0.037 14.2 0.2 0.098 12.9 0.2 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_M1 PF01433.15 KEZ46188.1 - 7.1e-133 443.4 1.7 9.5e-133 443.0 1.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KEZ46188.1 - 5e-72 242.8 0.0 8.7e-72 242.0 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KEZ46188.1 - 5.9e-21 74.8 4.1 8.1e-21 74.3 0.4 2.4 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 KEZ46188.1 - 0.074 12.8 0.4 0.46 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF45 PIGA PF08288.7 KEZ46189.1 - 1.5e-46 156.6 2.4 4.2e-46 155.2 0.4 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KEZ46189.1 - 4.4e-30 104.3 0.0 6.6e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEZ46189.1 - 5.1e-16 59.0 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KEZ46189.1 - 1.9e-13 50.5 0.3 3.7e-13 49.5 0.2 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KEZ46189.1 - 4.8e-11 43.0 0.0 8.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KEZ46189.1 - 2.4e-05 24.1 0.2 4.1e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KEZ46189.1 - 0.00048 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KEZ46189.1 - 0.1 12.0 0.2 0.29 10.5 0.1 1.9 1 1 0 1 1 1 0 Starch synthase catalytic domain Asp PF00026.18 KEZ46190.1 - 4.2e-39 134.6 0.0 9.5e-39 133.4 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ46190.1 - 1.6e-05 24.8 0.1 0.00018 21.5 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Cluap1 PF10234.4 KEZ46191.1 - 0.0032 16.6 0.1 0.0045 16.2 0.1 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Transposase_22 PF02994.9 KEZ46191.1 - 0.0052 15.3 0.9 0.008 14.7 0.6 1.2 1 0 0 1 1 1 1 L1 transposable element Tropomyosin PF00261.15 KEZ46191.1 - 0.008 15.2 2.0 0.013 14.5 1.4 1.3 1 0 0 1 1 1 1 Tropomyosin PspA_IM30 PF04012.7 KEZ46191.1 - 0.01 15.2 0.9 0.017 14.5 0.6 1.2 1 0 0 1 1 1 1 PspA/IM30 family DUF16 PF01519.11 KEZ46191.1 - 0.01 16.0 0.3 0.02 15.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF241 PF03087.9 KEZ46191.1 - 0.025 14.0 1.3 0.037 13.5 0.9 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function SlyX PF04102.7 KEZ46191.1 - 0.025 14.9 0.5 0.025 14.9 0.3 1.9 2 0 0 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 KEZ46191.1 - 0.042 13.6 2.0 0.073 12.8 1.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rho_Binding PF08912.6 KEZ46191.1 - 0.057 13.7 1.2 0.24 11.7 0.2 2.2 2 0 0 2 2 2 0 Rho Binding Sugarporin_N PF11471.3 KEZ46191.1 - 0.2 11.2 1.4 0.38 10.4 1.0 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension XhlA PF10779.4 KEZ46191.1 - 0.2 11.5 3.1 0.34 10.8 2.1 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF4140 PF13600.1 KEZ46191.1 - 0.43 11.0 3.7 0.57 10.6 1.7 1.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) RIC3 PF15361.1 KEZ46191.1 - 4.3 7.5 7.6 0.42 10.8 0.6 2.1 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 PHO4 PF01384.15 KEZ46192.1 - 1.2e-110 369.2 15.7 1.4e-110 369.0 10.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glyco_hydro_31 PF01055.21 KEZ46193.1 - 2.9e-67 227.4 0.3 4.3e-67 226.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Trypan_PARP PF05887.6 KEZ46193.1 - 4e-05 23.4 428.9 0.41 10.4 51.0 8.1 1 1 5 6 6 6 3 Procyclic acidic repetitive protein (PARP) WD40 PF00400.27 KEZ46195.1 - 4.5e-32 108.7 20.7 5.5e-08 32.4 0.0 8.1 6 1 0 6 6 6 5 WD domain, G-beta repeat Striatin PF08232.7 KEZ46195.1 - 1.3e-31 109.7 2.0 2.9e-31 108.5 1.4 1.6 1 0 0 1 1 1 1 Striatin family Cytochrom_D1 PF02239.11 KEZ46195.1 - 0.068 11.4 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain XPA_C PF05181.7 KEZ46196.1 - 2.3e-28 97.5 4.8 5e-28 96.4 3.3 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 KEZ46196.1 - 0.24 11.1 10.0 0.055 13.1 3.4 2.2 2 0 0 2 2 2 0 XPA protein N-terminal FYVE PF01363.16 KEZ46196.1 - 1.4 8.8 7.2 7 6.6 5.0 2.1 1 1 0 1 1 1 0 FYVE zinc finger Pho88 PF10032.4 KEZ46197.1 - 3.5e-76 254.7 0.0 3.9e-76 254.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ribosomal_L3 PF00297.17 KEZ46198.1 - 6.3e-115 383.0 7.1 7.6e-115 382.8 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 KEZ46199.1 - 1.6e-54 179.3 26.2 5.9e-08 32.0 0.0 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ46199.1 - 1.8e-52 174.8 47.6 1.7e-13 49.9 1.3 6.6 2 2 7 9 9 9 9 TPR repeat TPR_2 PF07719.12 KEZ46199.1 - 3.9e-47 154.4 18.8 1.9e-05 24.1 0.7 10.6 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46199.1 - 1.6e-36 121.3 17.1 8.2e-06 25.2 0.6 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46199.1 - 3e-32 110.5 11.9 5.4e-07 30.1 0.0 7.0 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ46199.1 - 6.8e-32 107.0 20.1 0.0017 18.3 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ46199.1 - 3.8e-28 95.3 9.4 0.00023 21.4 0.0 9.1 4 3 4 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ46199.1 - 4.4e-28 97.0 21.0 7.3e-07 29.0 0.8 6.8 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ46199.1 - 6.5e-23 79.5 16.3 0.00057 20.1 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46199.1 - 1.5e-22 79.7 17.3 0.00028 21.1 0.3 6.7 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46199.1 - 2.5e-20 70.6 12.1 0.0016 18.0 0.0 9.0 9 1 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 KEZ46199.1 - 3e-15 56.1 10.9 2.2e-08 34.0 1.5 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEZ46199.1 - 3.7e-14 52.3 9.2 0.0016 18.2 0.1 6.3 1 1 8 9 9 9 7 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ46199.1 - 1.6e-10 40.5 9.7 0.0011 18.1 1.1 4.6 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 KEZ46199.1 - 3.3e-07 30.3 0.3 0.11 12.5 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEZ46199.1 - 0.0031 17.3 0.7 1.2 9.0 0.0 4.2 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 KEZ46199.1 - 0.011 14.5 2.4 2.2 6.9 0.0 3.1 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.4 KEZ46199.1 - 0.012 15.0 3.1 1.1 8.7 0.0 3.3 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 KEZ46199.1 - 0.013 15.4 0.0 0.013 15.4 0.0 4.6 4 2 1 6 6 5 0 Tetratricopeptide repeat SNAP PF14938.1 KEZ46199.1 - 0.1 11.7 15.2 3.3 6.7 0.5 4.4 1 1 4 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 KEZ46199.1 - 0.15 12.0 19.5 2.1 8.4 0.0 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat GAS PF13851.1 KEZ46199.1 - 0.38 9.9 2.1 0.41 9.8 0.2 1.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding MIT PF04212.13 KEZ46199.1 - 0.74 9.7 17.9 2.3 8.1 0.1 6.3 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain DUF1751 PF08551.5 KEZ46200.1 - 1.7e-27 95.6 5.5 1.7e-27 95.6 3.8 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KEZ46200.1 - 0.0038 17.2 11.3 0.0075 16.2 7.8 1.5 1 0 0 1 1 1 1 Rhomboid family RseC_MucC PF04246.7 KEZ46200.1 - 0.7 9.4 4.9 0.86 9.1 0.1 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC WD40 PF00400.27 KEZ46201.1 - 7e-14 51.0 4.1 2.9e-05 23.7 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat LisH PF08513.6 KEZ46201.1 - 1.2e-06 28.0 0.1 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 LisH IKI3 PF04762.7 KEZ46201.1 - 0.091 10.5 0.0 0.29 8.9 0.0 1.7 2 0 0 2 2 2 0 IKI3 family NuiA PF07924.6 KEZ46202.1 - 0.059 13.2 0.1 0.7 9.7 0.1 2.0 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Chorismate_bind PF00425.13 KEZ46203.1 - 1.1e-88 296.9 0.0 7.5e-88 294.1 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KEZ46203.1 - 3.7e-28 98.2 0.1 4.9e-24 84.9 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region MFS_1 PF07690.11 KEZ46204.1 - 6.1e-40 137.0 38.5 6.1e-40 137.0 26.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ46204.1 - 4.1e-12 45.4 10.5 4.1e-12 45.4 7.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1072 PF06380.6 KEZ46204.1 - 0.66 9.6 3.5 0.43 10.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Sugar_tr PF00083.19 KEZ46205.1 - 1.5e-106 356.6 21.7 2.1e-106 356.1 15.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ46205.1 - 1.2e-24 86.7 27.2 1.2e-24 86.7 18.8 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 KEZ46205.1 - 0.013 14.0 8.3 0.012 14.2 0.9 2.4 2 0 0 2 2 2 0 LacY proton/sugar symporter AIP3 PF03915.8 KEZ46206.1 - 4.1e-159 530.0 4.1 6.5e-159 529.3 2.9 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 FliL PF03748.9 KEZ46206.1 - 0.007 16.3 0.1 0.037 14.0 0.1 2.3 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL DivIC PF04977.10 KEZ46206.1 - 0.023 14.1 7.9 0.17 11.4 0.3 3.4 2 1 1 3 3 3 0 Septum formation initiator DUF1664 PF07889.7 KEZ46206.1 - 0.15 11.8 7.8 0.16 11.7 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 KEZ46206.1 - 0.21 10.0 0.8 0.56 8.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Syntaxin_2 PF14523.1 KEZ46206.1 - 0.49 10.4 5.4 4.5 7.3 0.0 4.0 5 0 0 5 5 5 0 Syntaxin-like protein NPV_P10 PF05531.7 KEZ46206.1 - 1.2 9.4 7.9 1.8 8.8 0.2 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FAD_binding_3 PF01494.14 KEZ46207.1 - 5.7e-23 81.5 0.1 1.1e-22 80.5 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ46207.1 - 5.8e-05 22.1 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ46207.1 - 6.7e-05 22.8 0.2 0.00024 21.0 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ46207.1 - 0.0017 18.7 0.1 0.0045 17.3 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KEZ46207.1 - 0.0017 17.2 0.0 0.0038 16.0 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 KEZ46207.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KEZ46207.1 - 0.0059 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KEZ46207.1 - 0.0063 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 KEZ46207.1 - 0.0071 16.6 0.1 0.034 14.4 0.0 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain 3HCDH_N PF02737.13 KEZ46207.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 KEZ46207.1 - 0.015 14.3 0.1 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KEZ46207.1 - 0.035 14.0 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KEZ46207.1 - 0.042 14.2 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.1 KEZ46207.1 - 0.11 12.2 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Cellulase PF00150.13 KEZ46208.1 - 3e-48 164.4 0.3 3.9e-48 164.0 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 KEZ46208.1 - 0.018 14.3 0.2 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Ribosomal_S19 PF00203.16 KEZ46209.1 - 3.3e-23 81.0 0.1 4.4e-23 80.6 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 KEZ46210.1 - 6e-25 86.8 0.4 6e-25 86.8 0.2 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit ER_lumen_recept PF00810.13 KEZ46211.1 - 2e-53 180.8 10.8 3.1e-53 180.2 7.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KEZ46211.1 - 0.063 12.8 0.5 0.063 12.8 0.3 3.7 4 1 1 5 5 5 0 PQ loop repeat LicD PF04991.8 KEZ46212.1 - 3.3e-35 122.0 9.4 3.3e-35 122.0 6.5 3.9 2 2 0 2 2 2 1 LicD family CDC45 PF02724.9 KEZ46212.1 - 1.7 6.5 37.9 2.5 6.0 26.2 1.2 1 0 0 1 1 1 0 CDC45-like protein BC10 PF06726.7 KEZ46213.1 - 4.2e-14 52.3 12.0 6.9e-14 51.6 8.3 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 PRRSV_Env PF02340.10 KEZ46213.1 - 0.11 11.6 2.4 0.16 11.0 1.7 1.3 1 0 0 1 1 1 0 PRRSV putative envelope protein Rep_fac_C PF08542.6 KEZ46215.1 - 1.8e-25 88.7 0.1 9.2e-25 86.4 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEZ46215.1 - 1.2e-10 41.3 0.0 2.6e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KEZ46215.1 - 6.5e-06 26.3 0.1 1.6e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ46215.1 - 1.5e-05 25.1 0.7 0.00018 21.6 0.2 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ46215.1 - 8.4e-05 22.6 1.8 0.026 14.4 0.8 3.1 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KEZ46215.1 - 0.0032 17.5 0.2 0.17 11.9 0.1 2.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 KEZ46215.1 - 0.01 15.7 0.1 0.023 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 KEZ46215.1 - 0.014 14.9 0.1 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_10 PF12846.2 KEZ46215.1 - 0.051 12.9 0.2 2 7.7 0.0 2.5 2 1 0 3 3 3 0 AAA-like domain ABC_tran PF00005.22 KEZ46215.1 - 0.056 13.7 0.1 0.15 12.3 0.0 1.8 2 1 0 2 2 2 0 ABC transporter SNF2_N PF00176.18 KEZ46215.1 - 0.057 12.2 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 KEZ46215.1 - 0.071 11.6 0.0 0.14 10.6 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.10 KEZ46215.1 - 0.098 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 KEZ46215.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AMP-binding PF00501.23 KEZ46216.1 - 8.6e-92 307.6 0.3 1.2e-91 307.1 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ46216.1 - 3.7e-21 75.8 7.3 2.5e-19 69.9 1.1 3.6 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.1 KEZ46217.1 - 5.1e-60 202.7 6.0 5.1e-60 202.7 4.2 2.5 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KEZ46217.1 - 3.2e-45 154.2 1.3 6.5e-45 153.2 0.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KEZ46217.1 - 5.5e-44 150.2 3.0 5.5e-44 150.2 2.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KEZ46217.1 - 2.6e-21 76.4 0.7 2.6e-21 76.4 0.5 2.8 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KEZ46217.1 - 1.1e-17 63.9 31.9 1.1e-17 63.9 22.1 4.4 3 1 0 3 3 3 1 Disintegrin Pep_M12B_propep PF01562.14 KEZ46217.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide Ribosomal_L16 PF00252.13 KEZ46221.1 - 3.6e-29 101.1 0.2 5e-29 100.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 KEZ46222.1 - 5.5e-53 178.8 0.0 3.2e-52 176.3 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KEZ46222.1 - 6.5e-14 51.8 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KEZ46222.1 - 2.3e-10 40.7 0.0 6.9e-10 39.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KEZ46222.1 - 8.4e-07 28.0 0.0 2.2e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 KEZ46222.1 - 2.3e-06 27.2 0.0 4.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 KEZ46222.1 - 2.7e-06 27.5 0.0 9.3e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ46222.1 - 3.1e-06 28.0 0.3 2.3e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KEZ46222.1 - 0.00017 21.3 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEZ46222.1 - 0.00077 19.7 2.5 0.00082 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEZ46222.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ46222.1 - 0.0029 17.6 0.0 0.05 13.5 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain KTI12 PF08433.5 KEZ46222.1 - 0.019 14.1 0.0 0.049 12.8 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KEZ46222.1 - 0.02 14.6 0.6 0.11 12.1 0.5 2.0 1 1 1 2 2 2 0 NTPase AAA_33 PF13671.1 KEZ46222.1 - 0.031 14.1 0.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KEZ46222.1 - 0.056 13.4 2.7 0.13 12.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KEZ46222.1 - 0.067 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus GrpE PF01025.14 KEZ46224.1 - 1.9e-45 154.3 5.7 2.7e-45 153.8 3.9 1.2 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.7 KEZ46224.1 - 0.0091 15.3 2.4 0.013 14.9 1.7 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) TPD52 PF04201.10 KEZ46224.1 - 0.04 13.6 3.0 0.062 13.0 2.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family Bap31 PF05529.7 KEZ46224.1 - 0.17 11.3 2.2 0.24 10.8 1.5 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like IncA PF04156.9 KEZ46224.1 - 0.42 10.1 2.9 0.67 9.5 2.0 1.3 1 0 0 1 1 1 0 IncA protein Mito_carr PF00153.22 KEZ46225.1 - 9.9e-57 188.6 1.0 6.9e-20 70.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chorismate_synt PF01264.16 KEZ46226.1 - 4.9e-128 426.4 0.0 6e-128 426.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Chorion_2 PF03964.10 KEZ46226.1 - 0.022 15.2 2.6 0.83 10.2 0.2 2.4 2 0 0 2 2 2 0 Chorion family 2 BPL_LplA_LipB PF03099.14 KEZ46227.1 - 2.5e-12 46.9 0.0 4.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Pkinase PF00069.20 KEZ46228.1 - 1.5e-52 178.3 0.1 1.6e-36 125.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46228.1 - 3.5e-22 78.7 0.2 1.3e-20 73.6 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46228.1 - 1.5e-05 24.0 0.0 3.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ46228.1 - 0.0021 17.8 0.1 0.0021 17.8 0.1 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Glycos_transf_1 PF00534.15 KEZ46229.1 - 1.3e-33 115.8 0.0 1.6e-32 112.2 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KEZ46229.1 - 1.6e-12 47.7 0.2 2.9e-09 37.1 0.0 3.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KEZ46229.1 - 1.1e-08 35.4 0.4 1.1e-08 35.4 0.3 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 KEZ46229.1 - 5.7e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KEZ46229.1 - 6.3e-06 26.0 0.0 3.6e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 NACHT PF05729.7 KEZ46230.1 - 0.00022 20.9 0.1 0.00077 19.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KEZ46230.1 - 0.0082 16.1 0.0 0.03 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ank_4 PF13637.1 KEZ46230.1 - 0.016 15.7 0.0 0.059 13.9 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ46230.1 - 0.036 14.3 0.1 0.26 11.6 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_10 PF12846.2 KEZ46230.1 - 0.038 13.4 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KEZ46230.1 - 0.091 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KEZ46230.1 - 0.13 12.2 0.0 3.1 7.7 0.0 3.0 3 1 0 3 3 3 0 50S ribosome-binding GTPase IPK PF03770.11 KEZ46232.1 - 2.1e-55 187.4 0.0 6.2e-55 185.8 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase DAO PF01266.19 KEZ46233.1 - 1.8e-32 112.6 0.1 4e-32 111.5 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Oest_recep PF02159.10 KEZ46233.1 - 0.25 11.4 2.2 0.62 10.1 1.5 1.6 1 0 0 1 1 1 0 Oestrogen receptor CN_hydrolase PF00795.17 KEZ46234.1 - 1.7e-19 69.9 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HATPase_c_3 PF13589.1 KEZ46235.1 - 5.8e-11 42.2 0.0 1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KEZ46235.1 - 2.6e-08 33.5 0.0 4.8e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 KEZ46235.1 - 2.4e-05 24.0 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fungal_trans_2 PF11951.3 KEZ46236.1 - 6e-49 166.6 0.0 9.4e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46236.1 - 9.4e-07 28.6 14.1 1.6e-06 27.8 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.7 KEZ46238.1 - 3.1e-87 292.8 45.6 4.4e-87 292.3 26.2 2.4 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 KEZ46238.1 - 2e-21 76.0 0.8 4e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 NUC130/3NT domain Mito_carr PF00153.22 KEZ46238.1 - 0.019 14.6 0.0 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial carrier protein Tetraspannin PF00335.15 KEZ46239.1 - 0.00053 19.3 2.3 0.0028 16.9 0.0 2.1 2 0 0 2 2 2 1 Tetraspanin family FtsX PF02687.16 KEZ46239.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.9 2 1 1 3 3 3 0 FtsX-like permease family SNO PF01174.14 KEZ46240.1 - 1.5e-54 184.5 0.0 2.4e-53 180.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KEZ46240.1 - 9.6e-08 31.7 0.0 6e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KEZ46240.1 - 7e-05 22.3 0.0 0.0098 15.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KEZ46240.1 - 0.00011 21.7 0.1 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KEZ46240.1 - 0.00016 20.9 0.1 0.00038 19.7 0.0 1.6 2 0 0 2 2 2 1 Putative amidotransferase Peptidase_S51 PF03575.12 KEZ46240.1 - 0.023 14.4 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 DUF4154 PF13689.1 KEZ46240.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) HMGL-like PF00682.14 KEZ46241.1 - 4.4e-39 134.5 0.0 1.1e-38 133.2 0.0 1.6 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.20 KEZ46242.1 - 1.5e-61 207.6 0.0 2.1e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KEZ46242.1 - 8.7e-13 48.7 0.4 1.9e-12 47.6 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KEZ46242.1 - 7.3e-10 38.9 0.6 1.3e-09 38.0 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KEZ46242.1 - 0.065 13.1 0.4 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 HAS barrel domain DUF561 PF04481.7 KEZ46242.1 - 0.094 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) bZIP_1 PF00170.16 KEZ46243.1 - 4.9e-11 42.4 10.8 1e-10 41.3 7.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KEZ46243.1 - 0.00013 21.7 10.3 0.00013 21.7 7.2 2.2 2 0 0 2 2 2 1 Basic region leucine zipper MFS_1 PF07690.11 KEZ46244.1 - 1.9e-28 99.1 67.1 8e-15 54.3 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM176 PF14851.1 KEZ46244.1 - 0.18 11.4 0.2 0.4 10.3 0.1 1.5 1 0 0 1 1 1 0 FAM176 family AAA PF00004.24 KEZ46245.1 - 9.7e-18 64.6 0.0 2.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ46245.1 - 0.00063 19.8 0.1 0.003 17.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ46245.1 - 0.0016 18.4 0.1 0.0092 15.9 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KEZ46245.1 - 0.044 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEZ46245.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain TPR_12 PF13424.1 KEZ46246.1 - 1.8e-20 72.6 0.1 2.4e-12 46.6 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ46246.1 - 1.1e-18 67.0 0.0 1.8e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 KEZ46246.1 - 6.3e-12 44.5 0.0 0.00068 19.1 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ46246.1 - 5e-09 35.6 0.3 0.0014 18.1 0.0 3.3 3 1 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 KEZ46246.1 - 2.7e-08 33.1 0.0 0.017 14.9 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ46246.1 - 1e-07 31.6 0.0 0.0015 18.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 KEZ46246.1 - 2.4e-06 27.6 0.0 4.7e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain TPR_14 PF13428.1 KEZ46246.1 - 6.5e-06 26.3 0.0 0.29 11.8 0.0 3.9 2 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46246.1 - 8.2e-05 22.1 0.3 0.071 12.9 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46246.1 - 0.00016 21.2 0.1 0.14 12.0 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46246.1 - 0.00021 21.5 0.0 1.8 8.9 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_22 PF13401.1 KEZ46246.1 - 0.00065 19.8 0.0 0.0022 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KEZ46246.1 - 0.0026 18.5 0.0 0.013 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEZ46246.1 - 0.0062 16.7 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KEZ46246.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 KEZ46246.1 - 0.021 14.5 0.0 0.079 12.6 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KEZ46246.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KEZ46246.1 - 0.041 13.6 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.10 KEZ46246.1 - 0.045 12.6 0.0 0.34 9.7 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 KEZ46246.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin EmrE PF13536.1 KEZ46247.1 - 0.0064 16.6 1.0 0.013 15.6 0.7 1.4 1 0 0 1 1 1 1 Multidrug resistance efflux transporter TB2_DP1_HVA22 PF03134.14 KEZ46247.1 - 0.073 12.8 0.2 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Amidase PF01425.16 KEZ46248.1 - 8.6e-24 84.1 0.1 1.3e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 Amidase APH PF01636.18 KEZ46250.1 - 2e-19 70.2 0.0 6e-19 68.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ46250.1 - 0.00084 18.7 0.1 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 KEZ46250.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAD_binding_8 PF13450.1 KEZ46251.1 - 2.3e-11 43.5 0.4 4.4e-11 42.6 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KEZ46251.1 - 1.7e-08 33.7 2.3 2.7e-08 33.1 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ46251.1 - 1.5e-07 30.6 2.0 6.6e-07 28.5 1.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KEZ46251.1 - 1e-06 28.1 1.0 1.4e-06 27.6 0.3 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ46251.1 - 1.3e-05 25.3 0.1 0.00047 20.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ46251.1 - 1.6e-05 23.5 0.9 2.8e-05 22.7 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KEZ46251.1 - 4.2e-05 23.8 0.9 0.00013 22.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ46251.1 - 0.00014 21.0 0.9 0.00043 19.4 0.3 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KEZ46251.1 - 0.00038 19.6 1.1 0.0007 18.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ46251.1 - 0.00045 20.1 0.2 0.0031 17.4 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ46251.1 - 0.0053 15.7 0.7 0.0079 15.1 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.1 KEZ46251.1 - 0.033 13.1 0.1 4.2 6.1 0.2 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KEZ46251.1 - 0.096 11.5 2.6 0.18 10.6 1.9 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KEZ46252.1 - 3.3e-16 59.2 0.4 2.1e-15 56.6 0.3 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KEZ46252.1 - 0.00012 22.0 0.1 0.00033 20.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEZ46252.1 - 0.00068 19.4 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KEZ46252.1 - 0.00099 18.1 0.3 0.0076 15.1 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KEZ46252.1 - 0.0098 14.8 0.1 0.041 12.7 0.0 2.0 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ46252.1 - 0.022 14.6 0.5 0.038 13.8 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ46252.1 - 0.027 14.8 0.1 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ46252.1 - 0.04 12.7 0.0 0.07 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 KEZ46252.1 - 0.043 12.6 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Gcd10p PF04189.8 KEZ46253.1 - 8.3e-69 231.9 0.0 1.3e-67 228.1 0.0 2.1 1 1 0 1 1 1 1 Gcd10p family SAPS PF04499.10 KEZ46253.1 - 1.9 7.0 6.0 3.1 6.3 4.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein P21-Arc PF04062.9 KEZ46254.1 - 1.1e-77 259.7 0.0 1.2e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit AAA PF00004.24 KEZ46255.1 - 1.2e-15 57.8 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KEZ46255.1 - 1.5e-14 53.7 0.0 4.2e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KEZ46255.1 - 2.3e-12 46.9 0.0 2.7e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KEZ46255.1 - 9.9e-10 37.6 0.0 1e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KEZ46255.1 - 9.5e-07 28.4 0.0 3.2e-06 26.7 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 KEZ46255.1 - 1e-06 27.9 0.1 2.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KEZ46255.1 - 1.5e-06 28.3 0.1 3.2e-05 24.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KEZ46255.1 - 3e-06 27.3 0.1 0.0001 22.3 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KEZ46255.1 - 2.8e-05 23.7 0.0 5.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 KEZ46255.1 - 3.5e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KEZ46255.1 - 4.8e-05 22.2 0.0 0.19 10.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_11 PF13086.1 KEZ46255.1 - 9.1e-05 22.1 0.1 0.00053 19.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 KEZ46255.1 - 9.1e-05 22.1 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KEZ46255.1 - 0.00016 21.2 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 KEZ46255.1 - 0.00016 20.6 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KEZ46255.1 - 0.00019 21.1 0.3 0.002 17.8 0.1 2.7 2 1 1 3 3 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEZ46255.1 - 0.00035 20.1 0.0 0.0049 16.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEZ46255.1 - 0.0017 17.6 0.1 0.71 9.0 0.0 2.4 1 1 1 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 KEZ46255.1 - 0.0032 16.8 0.0 0.0079 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEZ46255.1 - 0.0037 17.5 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KEZ46255.1 - 0.0073 15.4 0.1 0.046 12.8 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEZ46255.1 - 0.0079 15.7 0.3 0.016 14.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KEZ46255.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ46255.1 - 0.017 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KEZ46255.1 - 0.022 14.1 0.0 1.8 7.9 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_17 PF13207.1 KEZ46255.1 - 0.027 15.3 0.0 0.067 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KEZ46255.1 - 0.028 13.9 0.0 1.8 8.0 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase SNF2_N PF00176.18 KEZ46255.1 - 0.035 12.8 0.0 4.2 6.0 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain IstB_IS21 PF01695.12 KEZ46255.1 - 0.041 13.2 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 KEZ46255.1 - 0.044 13.4 0.0 0.075 12.7 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase TAFII28 PF04719.9 KEZ46255.1 - 0.055 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region RNA_helicase PF00910.17 KEZ46255.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 KEZ46255.1 - 0.11 11.9 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 KEZ46255.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Fringe PF02434.11 KEZ46256.1 - 9.8e-07 28.2 2.8 2.6e-05 23.5 0.7 2.9 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 KEZ46256.1 - 0.0014 18.3 0.8 0.0034 17.0 0.6 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 KEZ46256.1 - 0.042 13.4 0.2 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 PAN-like domain Galactosyl_T PF01762.16 KEZ46256.1 - 0.11 12.0 0.5 0.68 9.5 0.1 1.9 1 1 1 2 2 2 0 Galactosyltransferase Asp PF00026.18 KEZ46257.1 - 1.1e-53 182.6 1.0 1.5e-53 182.1 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ46257.1 - 0.0001 22.3 0.0 0.00054 19.9 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KEZ46257.1 - 0.00058 19.4 0.1 0.24 10.9 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KEZ46257.1 - 0.0044 17.4 0.0 0.09 13.2 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease 2OG-FeII_Oxy PF03171.15 KEZ46258.1 - 0.0016 18.6 0.0 0.003 17.8 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KEZ46258.1 - 0.004 17.6 0.1 0.0069 16.8 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-U PF06728.8 KEZ46258.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Thioredoxin_6 PF13848.1 KEZ46259.1 - 3.8e-14 52.8 0.0 1.4e-12 47.7 0.0 2.4 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 KEZ46259.1 - 1.3e-09 37.6 0.0 1.1e-07 31.4 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Pro-kuma_activ PF09286.6 KEZ46260.1 - 1.7e-34 118.8 0.0 3.4e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Glyco_transf_25 PF01755.12 KEZ46260.1 - 1.6e-09 37.6 0.0 7.4e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Peptidase_S8 PF00082.17 KEZ46260.1 - 9e-09 34.8 0.0 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 KEZ46261.1 - 2.8e-16 59.6 2.2 5.3e-12 45.9 0.0 3.9 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ46261.1 - 4.7e-15 54.5 0.2 8.2e-07 28.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KEZ46261.1 - 2.3e-14 53.4 3.4 1.7e-09 37.9 0.0 5.2 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ46261.1 - 5.8e-11 42.2 7.6 1.4e-09 37.8 0.3 4.8 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ46261.1 - 2.4e-08 33.4 4.6 0.00092 19.2 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat DUF1442 PF07279.6 KEZ46261.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) RdRP PF05183.7 KEZ46263.1 - 6.5e-161 536.9 0.1 8.2e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase CDC45 PF02724.9 KEZ46264.1 - 0.043 11.8 6.2 0.073 11.0 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 KEZ46264.1 - 0.086 12.8 1.3 0.13 12.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BUD22 PF09073.5 KEZ46264.1 - 0.43 9.5 10.4 0.58 9.1 7.2 1.1 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.3 KEZ46264.1 - 0.58 9.1 2.8 0.81 8.6 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.7 KEZ46264.1 - 0.91 7.3 9.0 1.2 6.9 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.1 KEZ46264.1 - 1.6 8.2 4.7 4 7.0 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SDA1 PF05285.7 KEZ46264.1 - 6.8 5.8 12.5 20 4.3 8.6 1.6 1 1 0 1 1 1 0 SDA1 RRN3 PF05327.6 KEZ46264.1 - 10 4.1 5.4 14 3.6 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Histone PF00125.19 KEZ46265.1 - 2.1e-22 78.9 0.1 2.8e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KEZ46265.1 - 4.1e-05 23.5 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 KEZ46266.1 - 1.9e-10 40.3 0.1 4.2e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KEZ46266.1 - 1e-07 31.8 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ46266.1 - 2.3e-05 23.9 0.0 5e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ46266.1 - 4.4e-05 23.2 0.0 7.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mre11_DNA_bind PF04152.9 KEZ46267.1 - 1.1e-53 181.6 0.4 3.7e-53 179.9 0.0 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KEZ46267.1 - 2.8e-22 79.0 3.3 4.1e-22 78.5 2.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEZ46267.1 - 2.7e-06 27.2 0.0 6.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_binding_1 PF01035.15 KEZ46268.1 - 1.5e-08 34.2 0.3 7.9e-08 31.9 0.1 2.0 1 1 1 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain His_Phos_1 PF00300.17 KEZ46268.1 - 0.0015 18.6 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRN3 PF05327.6 KEZ46268.1 - 0.012 13.7 0.9 0.014 13.5 0.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.7 KEZ46268.1 - 0.041 13.6 9.8 0.056 13.1 6.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 KEZ46268.1 - 0.043 13.0 11.3 0.06 12.5 7.8 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 KEZ46268.1 - 0.087 11.9 3.3 0.12 11.4 2.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KEZ46268.1 - 0.19 11.9 13.6 0.43 10.8 9.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 KEZ46268.1 - 0.2 9.5 10.2 0.24 9.2 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KEZ46268.1 - 0.22 10.2 21.4 0.31 9.7 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 KEZ46268.1 - 0.23 10.6 8.2 0.3 10.3 5.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.3 KEZ46268.1 - 0.36 9.7 3.0 0.46 9.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sigma70_ner PF04546.8 KEZ46268.1 - 0.37 10.3 11.4 0.62 9.6 7.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleo_P87 PF07267.6 KEZ46268.1 - 0.55 8.8 4.1 0.73 8.4 2.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Daxx PF03344.10 KEZ46268.1 - 0.57 8.6 8.4 0.78 8.1 5.8 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KEZ46268.1 - 0.66 7.9 8.7 0.89 7.5 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 KEZ46268.1 - 1.4 9.2 15.8 3.2 8.1 10.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 KEZ46268.1 - 1.9 6.2 8.1 2.7 5.7 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_LMP1 PF05297.6 KEZ46268.1 - 2.2 7.1 6.9 2.9 6.7 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) GCIP PF13324.1 KEZ46268.1 - 3.8 6.6 8.3 5.9 6.0 5.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2076 PF09849.4 KEZ46268.1 - 4 7.4 11.1 2.8 7.9 6.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM176 PF14851.1 KEZ46268.1 - 4.4 6.9 6.4 7.8 6.1 4.4 1.4 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 KEZ46268.1 - 5.3 6.5 17.0 9.3 5.7 11.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 KEZ46268.1 - 7.1 6.8 14.6 15 5.8 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TRAP_alpha PF03896.11 KEZ46268.1 - 9.8 5.0 9.7 16 4.4 6.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Kinesin PF00225.18 KEZ46269.1 - 8.8e-90 300.7 0.0 8.8e-90 300.7 0.0 2.6 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 KEZ46269.1 - 8.8 5.3 59.3 0.008 15.3 6.5 8.0 5 3 1 7 7 7 0 Reovirus sigma C capsid protein NACHT PF05729.7 KEZ46270.1 - 4.5e-11 42.6 0.0 1.4e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.1 KEZ46270.1 - 0.0096 16.2 2.3 0.031 14.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KEZ46270.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEZ46270.1 - 0.018 15.8 0.0 0.073 13.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KEZ46270.1 - 0.023 14.6 2.7 2.6 7.9 0.0 3.5 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 KEZ46270.1 - 0.03 14.4 0.0 0.16 12.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KEZ46270.1 - 0.032 13.6 2.6 0.076 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain AAA_29 PF13555.1 KEZ46270.1 - 0.034 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KEZ46270.1 - 0.042 14.0 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase TSC22 PF01166.13 KEZ46270.1 - 0.059 13.3 0.3 0.19 11.6 0.2 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family AAA_18 PF13238.1 KEZ46270.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ank PF00023.25 KEZ46270.1 - 0.14 12.0 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat ABC_tran PF00005.22 KEZ46270.1 - 0.16 12.2 0.2 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter BRO1 PF03097.13 KEZ46271.1 - 7.4e-111 370.5 0.0 1.2e-110 369.8 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KEZ46271.1 - 4.3e-80 268.8 0.7 4.3e-80 268.8 0.5 2.1 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Cas_APE2256 PF09651.5 KEZ46271.1 - 0.072 12.8 1.6 0.32 10.7 0.0 2.7 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_APE2256) DUF500 PF04366.7 KEZ46272.1 - 2.7e-40 136.7 0.0 4.9e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Band_7 PF01145.20 KEZ46273.1 - 1.3e-16 61.0 0.0 1.3e-16 61.0 0.0 3.2 1 1 2 3 3 3 1 SPFH domain / Band 7 family FTA2 PF13095.1 KEZ46274.1 - 5.2e-11 42.5 0.0 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Isochorismatase PF00857.15 KEZ46278.1 - 9.3e-41 139.6 0.1 1e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF87 PF01935.12 KEZ46278.1 - 0.071 12.9 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Abhydrolase_6 PF12697.2 KEZ46279.1 - 1.8e-28 99.9 0.3 2.1e-28 99.7 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ46279.1 - 4.9e-15 55.5 0.1 2.4e-13 50.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ46279.1 - 4.6e-10 39.4 0.1 1.5e-09 37.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KEZ46279.1 - 6.6e-07 29.0 0.0 1.9e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 KEZ46279.1 - 0.004 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 KEZ46279.1 - 0.01 15.0 0.0 0.022 13.9 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KEZ46279.1 - 0.029 13.8 0.1 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 KEZ46279.1 - 0.03 13.5 0.1 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family EHN PF06441.7 KEZ46279.1 - 0.044 13.6 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Epoxide hydrolase N terminus MFS_1 PF07690.11 KEZ46280.1 - 3.5e-17 62.1 30.5 3.5e-17 62.1 21.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 KEZ46280.1 - 0.0019 16.4 4.1 0.0041 15.2 2.8 1.7 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2371 PF10177.4 KEZ46280.1 - 7 6.5 6.5 5.3 6.9 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Glyco_hydro_28 PF00295.12 KEZ46282.1 - 3.1e-38 131.5 9.6 3.1e-38 131.5 6.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Peptidase_M14 PF00246.19 KEZ46283.1 - 9.7e-77 258.2 0.1 1.3e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_16 PF00722.16 KEZ46283.1 - 3.6e-15 55.7 0.1 8.6e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1996 PF09362.5 KEZ46284.1 - 7.7e-90 300.6 1.0 9.1e-90 300.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) p450 PF00067.17 KEZ46285.1 - 2.9e-67 227.1 0.1 4e-66 223.4 0.0 1.9 1 1 1 2 2 2 2 Cytochrome P450 DUF3500 PF12006.3 KEZ46286.1 - 3.6e-99 331.6 0.0 4.3e-99 331.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Methyltransf_2 PF00891.13 KEZ46288.1 - 1e-30 106.6 0.0 1.9e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KEZ46288.1 - 0.00041 20.1 0.0 0.0065 16.2 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain Fungal_trans PF04082.13 KEZ46289.1 - 4.6e-18 65.0 0.5 8.2e-18 64.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3369 PF11849.3 KEZ46289.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) Cons_hypoth698 PF03601.9 KEZ46289.1 - 0.078 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MFS_1 PF07690.11 KEZ46290.1 - 9.8e-32 110.0 24.6 5.9e-28 97.5 14.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ46290.1 - 8.9e-12 44.3 15.9 1.4e-11 43.6 11.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4231 PF14015.1 KEZ46290.1 - 8.6 6.3 6.7 23 5.0 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.11 KEZ46291.1 - 3.2e-09 35.9 6.0 0.0012 17.6 1.2 3.2 2 2 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ46291.1 - 0.029 12.7 0.0 0.044 12.1 0.0 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein ADC PF06314.6 KEZ46292.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Acetyltransf_1 PF00583.19 KEZ46293.1 - 1.9e-14 53.4 0.0 3.3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEZ46293.1 - 2.8e-08 33.8 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEZ46293.1 - 3.8e-07 30.1 0.0 6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KEZ46293.1 - 5.7e-07 29.2 0.0 2.6e-06 27.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 KEZ46293.1 - 6.2e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KEZ46293.1 - 8e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KEZ46293.1 - 0.00018 21.6 0.0 0.00024 21.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KEZ46293.1 - 0.0065 16.4 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEZ46293.1 - 0.0093 15.8 0.1 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 KEZ46293.1 - 0.025 14.4 0.0 0.047 13.6 0.0 1.5 1 1 0 1 1 1 0 Touch receptor neuron protein Mec-17 NmrA PF05368.8 KEZ46294.1 - 3.4e-40 137.7 0.0 4.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ46294.1 - 2.2e-16 60.4 0.0 3.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KEZ46294.1 - 1.5e-08 33.7 0.0 2.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KEZ46294.1 - 1.9e-06 27.9 0.1 5e-06 26.5 0.1 1.6 1 1 1 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KEZ46294.1 - 4.3e-06 26.3 0.0 1.6e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KEZ46294.1 - 1.4e-05 24.8 0.1 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KEZ46294.1 - 0.00071 18.5 0.0 0.0048 15.8 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KEZ46294.1 - 0.001 18.0 0.0 0.003 16.5 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 KEZ46294.1 - 0.027 14.7 0.0 0.093 13.0 0.0 1.8 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KEZ46294.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus p450 PF00067.17 KEZ46295.1 - 5.3e-89 298.8 0.0 6.1e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhoQ_Sensor PF08918.5 KEZ46295.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 PhoQ Sensor Pyr_redox_3 PF13738.1 KEZ46296.1 - 2.5e-21 76.6 0.0 8.4e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ46296.1 - 1.7e-13 49.6 0.0 4.3e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ46296.1 - 1.4e-08 34.6 0.0 3.6e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ46296.1 - 1.2e-06 27.7 0.0 7.7e-05 21.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KEZ46296.1 - 0.00069 18.6 0.0 0.083 11.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KEZ46296.1 - 0.0017 18.1 0.0 0.0067 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KEZ46298.1 - 2.1e-91 306.6 0.0 2.8e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KEZ46298.1 - 8.4e-58 194.7 0.0 1.3e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 KEZ46298.1 - 1.4e-05 23.7 0.3 2.2e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KEZ46298.1 - 5.7e-05 22.1 0.2 9.4e-05 21.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KEZ46298.1 - 0.00038 19.6 0.0 0.0008 18.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ46298.1 - 0.00047 20.0 1.1 0.0014 18.5 0.2 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ46298.1 - 0.00099 19.0 0.1 0.013 15.4 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KEZ46298.1 - 0.0079 15.0 0.3 0.014 14.2 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 KEZ46298.1 - 0.021 13.9 0.2 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 KEZ46298.1 - 0.029 13.2 0.1 0.12 11.2 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ46298.1 - 0.036 14.4 0.0 0.082 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ46298.1 - 0.076 11.9 0.2 0.17 10.7 0.2 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 KEZ46298.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 KEZ46298.1 - 0.18 10.3 0.5 0.53 8.8 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.20 KEZ46299.1 - 8.5e-14 51.8 0.8 1.5e-13 51.0 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KEZ46299.1 - 2.4e-05 24.0 0.1 4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 KR domain CoA_binding PF02629.14 KEZ46300.1 - 7e-21 74.5 0.6 7e-21 74.5 0.4 2.4 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KEZ46300.1 - 5.9e-18 64.9 0.1 1e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KEZ46300.1 - 9.3e-09 35.0 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KEZ46300.1 - 0.0035 17.4 0.2 0.016 15.3 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 KEZ46301.1 - 2.8e-65 219.4 0.0 3.9e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KEZ46301.1 - 2.8e-18 65.9 0.4 5e-18 65.1 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KEZ46301.1 - 1.4e-12 47.3 0.0 2.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KEZ46301.1 - 2.2e-05 24.2 0.0 5.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 KEZ46301.1 - 0.0088 15.4 0.0 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KEZ46301.1 - 0.016 14.5 0.4 0.051 12.8 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 KEZ46301.1 - 0.064 12.7 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 RimK-like ATP-grasp domain adh_short_C2 PF13561.1 KEZ46302.1 - 2.1e-18 66.9 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KEZ46302.1 - 0.00016 21.6 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase HpcH_HpaI PF03328.9 KEZ46302.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Amidase PF01425.16 KEZ46303.1 - 4.7e-13 48.8 0.0 6.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Amidase FAD_binding_4 PF01565.18 KEZ46304.1 - 1.2e-31 109.0 0.1 1.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 KEZ46304.1 - 2.2e-08 33.7 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain MFS_1 PF07690.11 KEZ46306.1 - 3e-35 121.5 22.1 3e-35 121.5 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ46306.1 - 1.9e-05 23.4 36.9 0.0021 16.7 25.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter RPE65 PF03055.10 KEZ46307.1 - 2.1e-135 452.0 0.0 2.3e-135 451.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Cupin_2 PF07883.6 KEZ46308.1 - 9.7e-22 76.2 0.9 3.7e-14 51.9 0.3 2.8 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.17 KEZ46308.1 - 0.00032 20.1 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 KEZ46308.1 - 0.00063 19.4 1.1 1.2 8.8 0.2 2.6 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_3 PF05899.7 KEZ46308.1 - 0.00097 18.4 0.0 0.46 9.9 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF861) CENP-C_C PF11699.3 KEZ46308.1 - 0.005 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like FAD_binding_3 PF01494.14 KEZ46309.1 - 2.1e-17 63.2 0.0 5.2e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ46309.1 - 1.9e-16 59.9 2.1 1.9e-07 30.3 1.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ46309.1 - 1.1e-08 34.9 1.3 2.8e-08 33.6 0.4 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KEZ46309.1 - 1.9e-07 31.4 0.4 0.00015 22.0 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KEZ46309.1 - 6.8e-07 28.2 3.0 0.065 11.8 0.0 3.1 2 1 1 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.19 KEZ46309.1 - 2.1e-06 26.8 2.7 3.7e-06 26.0 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KEZ46309.1 - 2.5e-06 26.2 1.0 0.0032 16.0 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ46309.1 - 5.2e-06 26.4 2.0 9.2e-05 22.4 1.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ46309.1 - 6.1e-06 26.4 0.7 2.6e-05 24.3 0.5 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ46309.1 - 7.4e-05 21.8 2.6 0.078 11.8 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 KEZ46309.1 - 0.00015 20.9 4.1 0.00025 20.2 2.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KEZ46309.1 - 0.00018 20.7 1.6 0.067 12.2 0.4 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.17 KEZ46309.1 - 0.00039 19.3 1.8 0.0067 15.3 0.9 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KEZ46309.1 - 0.0023 17.7 0.6 0.014 15.1 0.4 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 KEZ46309.1 - 0.0024 17.0 0.8 0.0077 15.3 0.2 1.9 2 0 0 2 2 2 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 KEZ46309.1 - 0.015 14.6 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Strep_67kDa_ant PF06100.6 KEZ46309.1 - 0.032 12.5 0.2 0.065 11.5 0.1 1.4 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family 3HCDH_N PF02737.13 KEZ46309.1 - 0.038 13.6 1.5 0.061 12.9 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KEZ46309.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SE PF08491.5 KEZ46309.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase FAA_hydrolase PF01557.13 KEZ46310.1 - 2.4e-51 174.2 0.0 4e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ADH_zinc_N PF00107.21 KEZ46311.1 - 3.6e-34 117.1 0.6 5.7e-34 116.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ46311.1 - 4.7e-12 46.9 0.5 9.2e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ46311.1 - 1.6e-06 27.8 0.0 1.5e-05 24.7 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KEZ46311.1 - 0.023 14.7 0.1 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 KEZ46311.1 - 0.026 14.0 0.2 0.041 13.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HupF_HypC PF01455.13 KEZ46311.1 - 0.065 13.2 0.2 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 HupF/HypC family DUF676 PF05057.9 KEZ46312.1 - 0.0021 17.3 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF4032 PF13224.1 KEZ46312.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4032) Abhydrolase_6 PF12697.2 KEZ46312.1 - 0.096 12.5 1.3 0.64 9.8 1.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 KEZ46313.1 - 7.5e-12 45.6 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KEZ46313.1 - 4.8e-06 25.9 0.0 6.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DUF4246 PF14033.1 KEZ46316.1 - 3.6e-46 157.8 0.0 8.8e-30 103.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4246) p450 PF00067.17 KEZ46316.1 - 1.3e-30 106.3 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 KEZ46316.1 - 0.00047 20.1 0.1 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Alpha_GJ PF03229.8 KEZ46317.1 - 0.28 11.5 8.5 0.093 13.0 3.7 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J MFS_1 PF07690.11 KEZ46318.1 - 1.4e-36 125.9 28.8 1.4e-36 125.9 20.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEZ46318.1 - 0.0015 18.0 2.0 0.0015 18.0 1.4 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 ABM PF03992.11 KEZ46320.1 - 4.7e-08 32.9 2.0 0.00055 19.9 1.1 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Cyclase PF04199.8 KEZ46321.1 - 1.4e-14 54.1 0.2 3.9e-14 52.6 0.1 1.7 1 1 1 2 2 2 1 Putative cyclase Fungal_trans PF04082.13 KEZ46322.1 - 2.1e-16 59.5 0.0 4.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46322.1 - 1.6e-07 31.0 8.8 3e-07 30.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KEZ46323.1 - 1e-20 74.6 0.0 2e-16 60.6 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ46323.1 - 1.6e-17 62.9 0.5 1.9e-14 52.8 0.1 2.7 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KEZ46323.1 - 1.4e-06 27.5 0.1 9.7e-05 21.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KEZ46323.1 - 0.00022 21.1 0.0 0.00075 19.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ46323.1 - 0.00057 18.8 0.0 0.92 8.3 0.0 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ46323.1 - 0.0026 17.6 0.0 0.04 13.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ46323.1 - 0.0067 16.2 0.0 4.8 6.9 0.0 3.1 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 KEZ46323.1 - 0.0069 16.7 0.0 0.31 11.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KEZ46323.1 - 0.091 11.8 0.0 12 4.9 0.0 2.5 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 KEZ46323.1 - 0.097 12.0 0.1 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Clr5 PF14420.1 KEZ46324.1 - 0.00023 21.0 2.9 0.00044 20.0 2.0 1.5 1 0 0 1 1 1 1 Clr5 domain DUF4611 PF15387.1 KEZ46324.1 - 0.088 12.9 1.1 0.17 12.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 KEZ46324.1 - 0.14 11.7 1.1 0.29 10.7 0.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3129 PF11327.3 KEZ46325.1 - 1.4e-21 77.1 7.8 3.8e-21 75.7 5.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) DUF3129 PF11327.3 KEZ46326.1 - 4.3e-41 140.7 5.0 5.1e-41 140.5 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) I-set PF07679.11 KEZ46326.1 - 0.023 14.5 0.5 0.035 13.9 0.1 1.7 2 0 0 2 2 2 0 Immunoglobulin I-set domain V-set PF07686.12 KEZ46326.1 - 0.098 12.5 0.3 0.16 11.8 0.2 1.6 1 1 0 1 1 1 0 Immunoglobulin V-set domain Dynamin_N PF00350.18 KEZ46327.1 - 4.3e-08 33.1 0.0 1.8e-07 31.0 0.0 2.1 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KEZ46327.1 - 2.6e-06 27.3 0.0 0.0015 18.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KEZ46327.1 - 0.00017 20.8 0.0 0.00071 18.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KEZ46327.1 - 0.001 19.0 1.2 0.0039 17.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 KEZ46327.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF3420 PF11900.3 KEZ46327.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Miro PF08477.8 KEZ46327.1 - 0.063 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 KEZ46327.1 - 0.085 11.9 0.1 0.2 10.7 0.1 1.7 1 0 0 1 1 1 0 AIG1 family EHN PF06441.7 KEZ46328.1 - 1e-33 115.5 0.0 1.5e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KEZ46328.1 - 4.1e-10 39.9 0.0 5.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ46328.1 - 6.1e-07 29.2 0.0 8.1e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ank_2 PF12796.2 KEZ46329.1 - 5.2e-55 183.7 1.6 3.9e-12 46.3 0.1 7.1 3 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ46329.1 - 8.8e-38 126.2 25.9 2.6e-06 26.9 0.1 13.3 13 1 0 13 13 13 9 Ankyrin repeat Ank_4 PF13637.1 KEZ46329.1 - 6.4e-37 125.2 9.1 1.5e-08 34.9 0.1 8.4 6 1 4 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ46329.1 - 3e-36 119.8 9.0 3.4e-05 23.6 0.0 11.9 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.1 KEZ46329.1 - 1.4e-28 98.2 11.3 1.8e-05 24.8 0.0 9.1 5 1 4 9 9 9 7 Ankyrin repeats (many copies) F-box-like PF12937.2 KEZ46329.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Zn_clus PF00172.13 KEZ46330.1 - 1e-07 31.7 9.3 1.7e-07 31.0 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 KEZ46331.1 - 3.7e-60 203.2 4.5 3.7e-60 203.2 3.1 1.4 2 0 0 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.16 KEZ46331.1 - 0.059 12.9 13.8 0.1 12.0 1.9 2.6 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus COX15-CtaA PF02628.10 KEZ46331.1 - 0.08 11.7 5.2 0.18 10.5 3.6 1.7 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein Glyco_transf_28 PF03033.15 KEZ46332.1 - 8e-24 83.9 0.0 1.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KEZ46332.1 - 0.003 16.1 0.0 0.0046 15.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase COX2-transmemb PF09125.5 KEZ46334.1 - 0.051 13.1 0.6 0.051 13.1 0.4 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Metallophos PF00149.23 KEZ46335.1 - 6.8e-21 74.5 0.0 1.8e-20 73.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.2 KEZ46335.1 - 7.1e-12 45.5 0.1 1.8e-11 44.1 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ46335.1 - 8.9e-10 38.8 0.8 1.4e-05 25.4 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.7 KEZ46335.1 - 1.5e-09 37.6 0.1 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Ank PF00023.25 KEZ46335.1 - 1.8e-07 30.6 2.4 0.0037 17.0 0.2 4.1 3 0 0 3 3 3 1 Ankyrin repeat AAA_16 PF13191.1 KEZ46335.1 - 3.7e-07 30.3 1.5 7e-06 26.1 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain Abhydrolase_6 PF12697.2 KEZ46335.1 - 1.7e-06 28.0 0.1 3.8e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_5 PF13857.1 KEZ46335.1 - 0.00015 21.9 1.7 0.00038 20.6 0.3 2.5 2 1 1 3 3 2 1 Ankyrin repeats (many copies) AAA_18 PF13238.1 KEZ46335.1 - 0.00049 20.4 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ank_3 PF13606.1 KEZ46335.1 - 0.00065 19.6 0.4 0.22 11.8 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Abhydrolase_5 PF12695.2 KEZ46335.1 - 0.00093 18.9 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_17 PF13207.1 KEZ46335.1 - 0.0014 19.4 0.1 0.0062 17.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 KEZ46335.1 - 0.0018 18.4 0.0 0.0073 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ46335.1 - 0.0048 16.7 0.0 0.052 13.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KEZ46335.1 - 0.0064 16.2 0.1 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA PF00004.24 KEZ46335.1 - 0.0099 16.0 0.0 0.041 14.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.9 KEZ46335.1 - 0.01 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_14 PF13173.1 KEZ46335.1 - 0.031 14.1 0.0 0.099 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KEZ46335.1 - 0.059 12.2 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KEZ46335.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain EF1_GNE PF00736.14 KEZ46336.1 - 4.1e-28 96.8 0.8 6e-28 96.3 0.6 1.2 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KEZ46336.1 - 1e-10 41.5 6.9 2.4e-10 40.3 4.8 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region RabGAP-TBC PF00566.13 KEZ46337.1 - 1.8e-32 112.5 0.0 2.9e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cpn60_TCP1 PF00118.19 KEZ46338.1 - 9.5e-134 446.6 6.6 1.1e-133 446.3 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 KEZ46338.1 - 0.11 12.6 0.5 0.74 10.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain eIF2A PF08662.6 KEZ46339.1 - 7.6e-41 139.9 3.7 5.5e-38 130.6 0.2 4.1 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 KEZ46339.1 - 3.2e-06 26.9 0.0 6.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ46339.1 - 2.8e-05 24.0 0.0 6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KEZ46339.1 - 4.7e-05 22.9 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KEZ46339.1 - 7e-05 22.5 0.1 1.7 8.6 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat FA_desaturase PF00487.19 KEZ46340.1 - 2.5e-27 95.9 16.6 3.9e-27 95.3 11.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KEZ46340.1 - 2.2e-05 24.4 0.0 4.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) zf-C3HC4_3 PF13920.1 KEZ46341.1 - 2.7e-05 23.7 10.2 2.7e-05 23.7 7.1 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) SWIB PF02201.13 KEZ46342.1 - 4.4e-28 96.7 2.7 8.6e-28 95.8 0.8 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 KEZ46342.1 - 1e-15 57.2 2.7 1.5e-15 56.6 0.7 2.1 2 0 0 2 2 2 1 DEK C terminal domain Orexin_rec2 PF03827.8 KEZ46342.1 - 0.012 15.6 0.3 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Orexin receptor type 2 DUF572 PF04502.8 KEZ46342.1 - 0.096 11.8 5.7 0.13 11.5 4.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.8 KEZ46342.1 - 0.36 10.1 10.4 0.64 9.3 7.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ank_2 PF12796.2 KEZ46343.1 - 3e-104 341.5 0.2 5.5e-18 65.1 0.0 9.6 3 3 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ46343.1 - 3.3e-100 323.2 0.0 9.5e-08 31.4 0.0 17.9 18 1 0 18 18 18 14 Ankyrin repeat Ank_4 PF13637.1 KEZ46343.1 - 2.6e-84 276.2 15.1 1.2e-09 38.4 0.0 16.1 5 4 12 17 17 17 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 KEZ46343.1 - 3.7e-73 239.9 15.2 6.1e-13 48.5 0.0 14.7 7 3 6 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ46343.1 - 4.3e-68 218.4 1.2 2e-05 24.3 0.0 18.2 19 0 0 19 19 19 12 Ankyrin repeat CorA PF01544.13 KEZ46343.1 - 1.1e-06 27.8 0.0 2.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1903 PF08991.5 KEZ46344.1 - 4.3e-06 26.7 2.5 6e-06 26.3 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KEZ46344.1 - 1.8e-05 24.5 2.2 4e-05 23.4 1.5 1.6 1 0 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 KEZ46344.1 - 0.08 12.8 3.6 0.25 11.2 2.4 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 KEZ46344.1 - 0.13 12.2 2.7 0.23 11.5 1.9 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NatB_MDM20 PF09797.4 KEZ46345.1 - 4.2e-39 134.3 0.0 8.3e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit SapB_1 PF05184.10 KEZ46345.1 - 0.061 13.1 0.4 0.86 9.5 0.0 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 Ilm1 PF10311.4 KEZ46346.1 - 9.7e-61 204.0 0.4 1.1e-60 203.8 0.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 KEZ46347.1 - 3.6e-32 109.6 9.4 3.7e-07 29.5 0.0 5.9 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEZ46347.1 - 1.1e-16 61.2 0.0 2.4e-09 37.6 0.0 4.2 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEZ46347.1 - 0.0002 21.3 0.0 0.0054 16.7 0.0 2.8 2 1 1 3 3 3 1 Prenyltransferase-like Pkinase PF00069.20 KEZ46348.1 - 7e-68 228.5 0.2 1.1e-67 227.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46348.1 - 5.6e-40 137.0 0.0 8.2e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46348.1 - 2.6e-09 36.4 0.0 6.4e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KEZ46348.1 - 2.5e-06 27.4 4.5 0.038 13.7 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KEZ46348.1 - 0.015 14.3 1.5 0.084 11.9 0.0 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KEZ46348.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TRAPPC10 PF12584.3 KEZ46349.1 - 8.8e-18 64.2 0.0 1.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 KEZ46349.1 - 0.00041 19.9 0.2 0.00071 19.1 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 IF-2B PF01008.12 KEZ46350.1 - 4.1e-80 268.7 0.7 4.9e-80 268.5 0.5 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.23 KEZ46351.1 - 5.7e-23 81.4 0.1 9.4e-23 80.6 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KEZ46351.1 - 2e-18 66.1 0.0 3.4e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KEZ46351.1 - 0.00033 20.4 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 NDUF_B8 PF05821.6 KEZ46353.1 - 5.6e-06 26.1 1.8 1.3e-05 24.9 1.2 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF2205 PF10224.4 KEZ46354.1 - 2.4e-32 110.3 0.5 3.2e-32 109.9 0.3 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) AAA_32 PF13654.1 KEZ46354.1 - 0.02 13.5 0.1 0.022 13.4 0.1 1.0 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 KEZ46355.1 - 1.8e-24 86.1 25.7 1.5e-16 60.0 6.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily 7tm_2 PF00002.19 KEZ46356.1 - 2.3e-12 46.5 9.6 2.3e-12 46.5 6.6 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 KEZ46356.1 - 4.3e-09 35.6 10.7 4.3e-09 35.6 7.4 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 KEZ46356.1 - 3.6e-08 33.2 11.8 6.4e-08 32.3 8.2 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Peptidase_M56 PF05569.6 KEZ46356.1 - 0.29 10.0 1.8 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 zf-C2H2 PF00096.21 KEZ46358.1 - 0.0043 17.3 1.3 0.013 15.8 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ46358.1 - 0.034 14.4 1.1 0.034 14.4 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Evr1_Alr PF04777.8 KEZ46359.1 - 2.5e-25 88.1 0.0 3.7e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family DUF2448 PF10476.4 KEZ46359.1 - 0.035 13.6 0.0 0.78 9.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Proteasome PF00227.21 KEZ46360.1 - 6e-48 162.6 0.3 7.1e-48 162.4 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Dot_icm_IcmQ PF09475.5 KEZ46361.1 - 0.039 13.1 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Cyclin PF08613.6 KEZ46362.1 - 3.3e-39 134.6 3.6 7e-23 81.6 0.1 2.6 3 0 0 3 3 3 2 Cyclin BUD22 PF09073.5 KEZ46362.1 - 0.042 12.9 3.4 0.06 12.4 2.3 1.3 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.5 KEZ46362.1 - 0.067 13.7 8.9 0.17 12.4 6.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.9 KEZ46362.1 - 0.085 10.8 9.6 0.045 11.7 4.8 1.7 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.1 KEZ46362.1 - 1 9.6 10.3 3.1 8.1 7.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KEZ46362.1 - 1.2 8.6 7.1 2.3 7.8 4.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 KEZ46362.1 - 1.6 8.1 8.8 3.1 7.3 6.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin BTV_NS2 PF04514.7 KEZ46362.1 - 8.9 5.0 7.6 15 4.3 5.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Acetyltransf_2 PF00797.12 KEZ46363.1 - 5e-34 117.9 0.1 2.3e-32 112.4 0.0 2.9 1 1 1 2 2 2 1 N-acetyltransferase YbjQ_1 PF01906.12 KEZ46364.1 - 9.7e-28 96.6 0.1 1.2e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding DPPIV_N PF00930.16 KEZ46365.1 - 7.9e-96 320.7 0.2 1.1e-95 320.2 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KEZ46365.1 - 2.5e-54 183.7 0.7 4.4e-54 182.9 0.3 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KEZ46365.1 - 3e-09 36.7 0.1 7.2e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEZ46365.1 - 0.00069 19.1 0.6 0.0042 16.5 0.2 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 KEZ46365.1 - 0.026 13.8 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Clathrin PF00637.15 KEZ46366.1 - 1.6e-199 653.5 26.9 9.8e-33 112.7 2.2 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KEZ46366.1 - 3.4e-31 106.9 0.1 1.5e-30 104.9 0.1 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 KEZ46366.1 - 3.9e-22 76.9 3.5 0.0022 18.1 0.0 6.8 7 0 0 7 7 7 5 Clathrin propeller repeat TPR_12 PF13424.1 KEZ46366.1 - 2.9e-05 23.9 3.6 1.1 9.1 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46366.1 - 9.4e-05 21.9 3.4 35 4.5 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46366.1 - 0.041 14.2 5.0 8.6 6.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Ank_3 PF13606.1 KEZ46366.1 - 0.075 13.3 0.1 1.8 9.0 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat TPR_14 PF13428.1 KEZ46366.1 - 0.26 12.0 10.9 79 4.3 0.0 8.1 8 1 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46366.1 - 0.4 10.3 5.1 11 5.8 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46366.1 - 3.6 7.7 10.2 4.4 7.4 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat SET PF00856.23 KEZ46367.1 - 3.7e-12 46.8 0.6 7.5e-10 39.3 0.1 2.7 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 KEZ46367.1 - 2.9e-07 30.0 14.1 0.00012 21.6 0.0 3.8 5 0 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 KEZ46367.1 - 0.00011 21.8 0.4 0.00011 21.8 0.3 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46367.1 - 0.00064 20.3 0.8 0.00064 20.3 0.6 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46367.1 - 0.001 18.5 5.9 0.089 12.4 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46367.1 - 0.0013 18.3 7.4 0.015 15.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46367.1 - 0.0029 17.9 0.3 0.0075 16.5 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ46367.1 - 0.0043 17.5 5.5 0.068 13.8 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ46367.1 - 0.015 15.2 5.1 0.094 12.6 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEZ46367.1 - 1.5 8.7 4.1 0.55 10.1 0.3 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Hum_adeno_E3A PF05393.6 KEZ46368.1 - 0.0046 16.6 0.1 0.0088 15.6 0.1 1.5 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein DUF1049 PF06305.6 KEZ46368.1 - 0.03 13.7 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) YtpI PF14007.1 KEZ46368.1 - 0.04 13.8 0.2 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 YtpI-like protein MSC PF09402.5 KEZ46368.1 - 0.042 12.5 0.0 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Shisa PF13908.1 KEZ46368.1 - 0.054 13.6 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator GP41 PF00517.12 KEZ46368.1 - 0.1 12.1 0.4 0.17 11.3 0.3 1.3 1 1 0 1 1 1 0 Retroviral envelope protein P12 PF12669.2 KEZ46368.1 - 0.17 12.1 1.8 0.54 10.5 1.2 1.8 1 0 0 1 1 1 0 Virus attachment protein p12 family TMEM154 PF15102.1 KEZ46368.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family DUF2910 PF11139.3 KEZ46368.1 - 0.19 10.8 2.8 0.29 10.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Synaptobrevin PF00957.16 KEZ46368.1 - 7.1 6.3 5.7 11 5.7 3.9 1.2 1 0 0 1 1 1 0 Synaptobrevin hDGE_amylase PF14701.1 KEZ46369.1 - 8.6e-154 512.4 0.0 1.1e-153 512.1 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KEZ46369.1 - 3.5e-117 391.2 0.0 5.3e-117 390.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KEZ46369.1 - 2.8e-83 279.0 0.0 4.1e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KEZ46369.1 - 4.7e-26 90.4 0.0 1.3e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KEZ46369.1 - 0.044 13.1 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 KEZ46370.1 - 4.4e-43 146.7 0.0 1e-42 145.5 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KEZ46370.1 - 5.3e-39 133.3 0.1 8.4e-39 132.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF2365 PF10157.4 KEZ46371.1 - 0.015 15.1 1.0 0.06 13.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Pam17 PF08566.5 KEZ46372.1 - 3.9e-63 212.2 0.0 6.1e-63 211.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 MoeZ_MoeB PF05237.8 KEZ46373.1 - 1.3e-21 75.9 0.9 4.9e-20 70.9 0.7 2.3 1 1 0 1 1 1 1 MoeZ/MoeB domain ThiF PF00899.16 KEZ46373.1 - 2.2e-15 56.6 4.0 7.6e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 ThiF family Rhodanese PF00581.15 KEZ46373.1 - 8.3e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox PF00070.22 KEZ46373.1 - 0.0048 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KEZ46373.1 - 0.023 14.7 0.4 0.078 13.0 0.3 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KEZ46373.1 - 0.034 13.1 0.6 0.053 12.5 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain IFP_35_N PF07334.8 KEZ46373.1 - 0.056 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SLX9 PF15341.1 KEZ46374.1 - 4.3e-34 117.5 0.1 7.1e-34 116.8 0.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Peptidase_C48 PF02902.14 KEZ46375.1 - 9.3e-17 61.3 0.0 3.8e-16 59.3 0.0 2.0 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.13 KEZ46375.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Adenovirus endoprotease NAAA-beta PF15508.1 KEZ46376.1 - 1e-20 73.8 0.0 2.9e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase PepSY_TM_2 PF13703.1 KEZ46376.1 - 0.2 11.8 1.3 0.41 10.8 0.2 1.9 2 0 0 2 2 2 0 PepSY-associated TM helix MFS_1 PF07690.11 KEZ46377.1 - 6.4e-35 120.5 62.3 3.3e-33 114.8 40.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3611 PF12263.3 KEZ46377.1 - 0.24 10.7 5.7 0.51 9.7 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Fungal_trans_2 PF11951.3 KEZ46378.1 - 2.6e-26 92.1 0.0 6.2e-26 90.8 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46378.1 - 2.2e-06 27.4 10.8 4.1e-06 26.5 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNR PF02012.15 KEZ46379.1 - 8.6 6.6 6.9 0.42 10.6 0.1 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat SKG6 PF08693.5 KEZ46380.1 - 0.0041 16.3 2.5 0.0084 15.4 1.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1517 PF07466.6 KEZ46380.1 - 0.046 12.7 0.7 0.074 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) MFS_1 PF07690.11 KEZ46382.1 - 2.7e-15 55.9 17.6 2.7e-15 55.9 12.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 KEZ46383.1 - 2.5e-57 194.4 0.5 3.1e-57 194.1 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.17 KEZ46384.1 - 2.5e-72 243.9 0.0 3.7e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KEZ46385.1 - 4.7e-57 193.5 0.0 6e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KEZ46387.1 - 5.7e-59 199.5 0.0 7.9e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KEZ46387.1 - 3.8e-05 24.5 0.0 8.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 KEZ46388.1 - 6.7e-15 54.6 0.3 9.8e-15 54.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ46389.1 - 1.2e-30 106.4 22.4 3.6e-28 98.3 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KEZ46389.1 - 7.6e-06 24.5 7.6 0.073 11.4 2.7 3.3 1 1 0 3 3 3 3 MFS/sugar transport protein UPF0697 PF15117.1 KEZ46390.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 HMGL-like PF00682.14 KEZ46392.1 - 2.1e-31 109.4 0.0 4.2e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Fungal_trans PF04082.13 KEZ46392.1 - 5.9e-18 64.6 0.1 1.3e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 KEZ46392.1 - 1.9e-11 43.5 0.0 1.9e-10 40.3 0.0 2.2 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family Zn_clus PF00172.13 KEZ46392.1 - 2.7e-07 30.3 10.2 5.3e-07 29.4 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSase_L_chain PF00289.17 KEZ46393.1 - 3.1e-33 114.1 0.2 7.3e-33 112.9 0.0 1.7 2 1 1 3 3 3 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D2 PF02786.12 KEZ46393.1 - 1.4e-18 67.0 0.1 2.2e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 KEZ46393.1 - 2e-06 27.6 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KEZ46393.1 - 9.4e-06 24.5 0.0 1.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KEZ46393.1 - 0.0027 17.0 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KEZ46393.1 - 0.0054 16.1 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KEZ46393.1 - 0.0094 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Aldedh PF00171.17 KEZ46395.1 - 4.9e-141 470.2 0.0 8.8e-141 469.3 0.0 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ46395.1 - 0.066 11.9 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) ADH_zinc_N PF00107.21 KEZ46396.1 - 2.2e-24 85.4 0.3 5e-24 84.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ46396.1 - 2.9e-09 36.6 0.1 7.1e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 KEZ46396.1 - 0.00019 21.0 0.4 0.00034 20.2 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KEZ46396.1 - 0.024 14.6 0.5 0.057 13.4 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KEZ46396.1 - 0.044 12.9 0.2 0.083 12.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KEZ46396.1 - 0.056 12.8 0.2 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 KEZ46396.1 - 0.16 12.5 0.7 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_61 PF03443.9 KEZ46397.1 - 4.2e-62 209.7 0.1 5.2e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Nitrate_red_gam PF02665.9 KEZ46398.1 - 0.11 11.8 0.1 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SKG6 PF08693.5 KEZ46398.1 - 0.12 11.6 0.3 0.22 10.8 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.16 KEZ46398.1 - 0.71 9.7 2.5 1.6 8.6 1.7 1.6 1 0 0 1 1 1 0 Gram positive anchor ABC_tran PF00005.22 KEZ46399.1 - 8.9e-36 123.2 0.1 1.3e-17 64.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 KEZ46399.1 - 3.3e-10 39.8 22.1 0.0066 15.8 0.5 4.1 2 2 2 4 4 4 4 ABC transporter transmembrane region AAA_21 PF13304.1 KEZ46399.1 - 1.5e-08 34.9 1.0 0.00045 20.2 0.5 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 KEZ46399.1 - 2.8e-08 33.2 0.3 0.00045 19.5 0.2 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KEZ46399.1 - 3.2e-08 33.7 0.6 0.012 15.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KEZ46399.1 - 1.5e-06 27.7 0.2 0.012 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ46399.1 - 2.4e-06 27.6 0.6 0.047 13.6 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KEZ46399.1 - 3.2e-06 26.2 2.2 0.0071 15.2 0.2 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein SbcCD_C PF13558.1 KEZ46399.1 - 1.3e-05 24.9 0.2 0.12 12.2 0.0 3.6 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KEZ46399.1 - 3.4e-05 23.0 1.5 0.01 15.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KEZ46399.1 - 0.00018 21.0 0.7 0.00097 18.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 KEZ46399.1 - 0.00041 20.0 0.6 1.1 8.8 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_29 PF13555.1 KEZ46399.1 - 0.00051 19.5 2.5 0.0018 17.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 KEZ46399.1 - 0.00058 18.5 2.8 0.48 8.9 0.1 3.2 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 KEZ46399.1 - 0.0021 17.6 1.0 0.27 10.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KEZ46399.1 - 0.0032 17.3 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KEZ46399.1 - 0.004 17.3 0.3 0.37 10.9 0.0 3.5 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KEZ46399.1 - 0.0049 16.3 4.2 0.47 9.8 0.0 2.9 3 0 0 3 3 2 1 AAA-like domain Mg_chelatase PF01078.16 KEZ46399.1 - 0.0052 15.9 0.4 1.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KEZ46399.1 - 0.0054 16.1 0.0 12 5.3 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.14 KEZ46399.1 - 0.006 16.0 2.4 0.96 8.8 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 KEZ46399.1 - 0.0094 15.0 1.2 1.2 8.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.24 KEZ46399.1 - 0.02 14.3 0.3 3.1 7.2 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_18 PF13238.1 KEZ46399.1 - 0.022 15.0 0.2 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KEZ46399.1 - 0.031 14.4 0.5 8.1 6.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_15 PF13175.1 KEZ46399.1 - 0.036 13.1 0.1 0.41 9.6 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.7 KEZ46399.1 - 0.041 13.1 1.2 0.69 9.1 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_17 PF13207.1 KEZ46399.1 - 0.041 14.6 0.4 3.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KEZ46399.1 - 0.042 13.3 0.0 5.5 6.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Miro PF08477.8 KEZ46399.1 - 0.044 14.2 0.6 0.78 10.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 KEZ46399.1 - 0.045 13.6 0.2 5.7 6.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KEZ46399.1 - 0.072 12.7 0.4 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.1 KEZ46399.1 - 0.095 13.0 0.7 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KEZ46399.1 - 0.11 11.3 0.3 8.6 5.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KEZ46399.1 - 0.12 12.1 2.6 0.63 9.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 CbiA PF01656.18 KEZ46399.1 - 0.22 10.9 3.0 8.8 5.6 0.1 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KEZ46399.1 - 0.22 11.1 2.9 1.5 8.5 0.1 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2207 PF09972.4 KEZ46399.1 - 0.24 9.9 5.1 1.1 7.7 0.2 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 KEZ46400.1 - 8.5e-12 44.4 3.9 8.9e-11 41.0 0.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ46400.1 - 9.7e-07 27.7 1.4 1.9e-06 26.7 1.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KEZ46400.1 - 0.0012 17.3 0.2 0.0048 15.3 0.0 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 KEZ46400.1 - 0.007 16.1 0.2 0.031 14.0 0.0 2.2 2 0 0 2 2 2 1 MFS_1 like family Acyl_transf_3 PF01757.17 KEZ46400.1 - 1.9 7.2 8.3 0.052 12.3 0.8 1.9 3 0 0 3 3 3 0 Acyltransferase family DegT_DnrJ_EryC1 PF01041.12 KEZ46402.1 - 1.9e-22 79.8 0.0 4.9e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family ABC_membrane PF00664.18 KEZ46403.1 - 9.4e-12 44.9 0.4 1.3e-11 44.4 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Cas_Cmr5 PF09701.5 KEZ46403.1 - 0.027 14.6 0.0 0.07 13.3 0.0 1.7 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Pectate_lyase_3 PF12708.2 KEZ46404.1 - 3.1e-33 115.7 1.2 3.6e-20 73.0 0.0 2.8 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KEZ46404.1 - 0.0001 21.7 1.6 0.16 11.4 0.2 3.2 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Ecm33 PF12454.3 KEZ46405.1 - 0.024 14.4 1.2 0.053 13.4 0.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein LysM PF01476.15 KEZ46406.1 - 6e-42 141.2 14.7 2.8e-08 33.5 0.1 5.2 5 0 0 5 5 5 5 LysM domain HTH_28 PF13518.1 KEZ46406.1 - 1.6e-05 24.8 0.6 3.1 7.8 0.0 4.1 4 0 0 4 4 4 2 Helix-turn-helix domain HTH_23 PF13384.1 KEZ46406.1 - 0.0067 16.0 0.1 43 3.9 0.0 4.1 4 0 0 4 4 4 0 Homeodomain-like domain SurA_N PF09312.6 KEZ46406.1 - 0.0086 15.9 0.3 30 4.5 0.0 3.8 4 0 0 4 4 4 0 SurA N-terminal domain HTH_Tnp_1 PF01527.15 KEZ46406.1 - 0.013 15.4 0.0 2.7 8.0 0.0 3.7 4 0 0 4 4 4 0 Transposase DUF3071 PF11268.3 KEZ46406.1 - 0.02 14.6 0.0 31 4.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3071) Aldo_ket_red PF00248.16 KEZ46407.1 - 5e-54 183.0 0.0 6.6e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NACHT PF05729.7 KEZ46408.1 - 4.9e-10 39.3 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KEZ46408.1 - 2e-05 24.6 0.0 9.2e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KEZ46408.1 - 0.00016 21.3 0.0 0.00043 19.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KEZ46408.1 - 0.00076 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ46408.1 - 0.00099 19.9 0.0 0.0048 17.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEZ46408.1 - 0.0018 17.7 0.0 0.0064 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain WD40 PF00400.27 KEZ46408.1 - 0.0021 17.8 10.9 9.2 6.3 0.1 6.6 6 0 0 6 6 6 0 WD domain, G-beta repeat NB-ARC PF00931.17 KEZ46408.1 - 0.0049 15.7 0.0 0.0093 14.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 KEZ46408.1 - 0.0081 15.8 0.0 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_33 PF13671.1 KEZ46408.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KEZ46408.1 - 0.022 14.9 0.1 0.077 13.1 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.1 KEZ46408.1 - 0.022 15.0 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KEZ46408.1 - 0.022 14.2 0.0 0.074 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 KEZ46408.1 - 0.025 13.3 0.0 0.066 11.9 0.0 1.6 2 0 0 2 2 2 0 ArgK protein APS_kinase PF01583.15 KEZ46408.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 KEZ46408.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KEZ46408.1 - 0.14 12.3 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KEZ46408.1 - 0.17 12.1 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KEZ46408.1 - 0.19 10.7 0.1 0.44 9.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RdRP PF05183.7 KEZ46410.1 - 2e-111 373.4 0.0 2.5e-111 373.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Fungal_trans PF04082.13 KEZ46412.1 - 2.6e-17 62.5 0.6 1.5e-16 60.1 0.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46412.1 - 1e-08 34.9 12.0 2.2e-08 33.8 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1180 PF06679.7 KEZ46412.1 - 0.21 11.4 1.9 0.52 10.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_1 PF00232.13 KEZ46413.1 - 4.4e-99 331.7 0.5 1.2e-63 214.8 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 Sugar_tr PF00083.19 KEZ46414.1 - 8.9e-76 255.2 19.0 1e-75 255.0 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ46414.1 - 2.5e-21 75.8 20.4 2.5e-21 75.8 14.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily EMP70 PF02990.11 KEZ46414.1 - 0.45 8.9 6.4 0.44 8.9 3.7 1.4 1 1 0 1 1 1 0 Endomembrane protein 70 IU_nuc_hydro PF01156.14 KEZ46415.1 - 3.1e-72 243.4 0.1 3.8e-72 243.1 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Abhydrolase_4 PF08386.5 KEZ46416.1 - 1.1e-21 76.6 0.0 1.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KEZ46416.1 - 4.8e-11 42.6 0.0 2.3e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KEZ46416.1 - 2.9e-08 33.8 0.0 7.1e-07 29.3 0.0 2.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1237 PF06824.6 KEZ46417.1 - 3.1e-146 487.2 0.0 8.2e-144 479.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1237) AAA PF00004.24 KEZ46418.1 - 1.6e-54 183.6 0.0 2.1e-43 147.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KEZ46418.1 - 5.6e-26 90.3 0.2 1.3e-25 89.2 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KEZ46418.1 - 1.5e-08 34.8 6.9 0.0023 17.9 0.0 4.6 3 2 2 5 5 4 2 AAA ATPase domain NACHT PF05729.7 KEZ46418.1 - 2.5e-07 30.5 0.2 0.00056 19.6 0.0 3.5 3 1 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 KEZ46418.1 - 2.8e-07 31.3 0.4 0.023 15.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KEZ46418.1 - 1e-06 28.6 0.0 0.0089 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KEZ46418.1 - 5.6e-06 26.5 0.2 0.13 12.3 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KEZ46418.1 - 1.3e-05 25.1 0.0 0.24 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KEZ46418.1 - 1.4e-05 25.3 0.0 0.009 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ46418.1 - 2.4e-05 24.1 0.2 0.12 12.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEZ46418.1 - 3.3e-05 23.7 0.0 0.4 10.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KEZ46418.1 - 3.5e-05 23.4 0.0 2 8.2 0.0 4.2 3 0 0 3 3 3 2 Part of AAA domain Zeta_toxin PF06414.7 KEZ46418.1 - 4.2e-05 22.7 0.0 0.099 11.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KEZ46418.1 - 6.2e-05 22.4 4.9 1.9 7.8 0.1 4.3 2 2 0 4 4 4 2 AAA domain UPF0079 PF02367.12 KEZ46418.1 - 9.2e-05 22.0 0.0 0.0024 17.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 KEZ46418.1 - 0.00012 21.2 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 KEZ46418.1 - 0.00033 19.6 0.0 0.0098 14.8 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 KEZ46418.1 - 0.0013 19.0 0.0 0.67 10.2 0.0 2.9 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 KEZ46418.1 - 0.0013 18.6 0.0 0.58 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KEZ46418.1 - 0.0017 18.4 0.0 0.52 10.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 KEZ46418.1 - 0.0027 17.4 0.1 0.35 10.5 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 KEZ46418.1 - 0.0033 17.5 0.0 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 KEZ46418.1 - 0.0043 16.4 0.2 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KEZ46418.1 - 0.01 15.3 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 1 0 FtsK/SpoIIIE family TIP49 PF06068.8 KEZ46418.1 - 0.011 14.4 0.0 0.88 8.2 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus Mg_chelatase PF01078.16 KEZ46418.1 - 0.014 14.5 0.1 0.68 9.0 0.0 2.5 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI SKI PF01202.17 KEZ46418.1 - 0.017 14.9 0.1 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase KaiC PF06745.8 KEZ46418.1 - 0.021 13.9 0.0 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.1 KEZ46418.1 - 0.044 13.3 0.1 0.29 10.7 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KEZ46418.1 - 0.056 12.9 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 KEZ46418.1 - 0.073 12.6 0.8 6.7 6.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KEZ46418.1 - 0.073 12.5 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KEZ46418.1 - 0.08 12.3 0.8 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 KEZ46418.1 - 0.085 11.8 0.1 1.8 7.4 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain KTI12 PF08433.5 KEZ46418.1 - 0.097 11.8 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_3 PF07726.6 KEZ46418.1 - 0.15 11.6 0.0 6.6 6.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KEZ46418.1 - 0.28 10.3 0.0 0.72 9.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 KEZ46418.1 - 0.35 9.6 0.0 6.5 5.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MCM PF00493.18 KEZ46419.1 - 3.9e-134 446.6 0.0 5.5e-134 446.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEZ46419.1 - 9.2e-23 81.0 0.8 2.5e-22 79.6 0.6 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEZ46419.1 - 1.4e-07 30.8 0.0 1.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KEZ46419.1 - 3.5e-06 26.7 0.0 1.2e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KEZ46419.1 - 0.034 13.7 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KEZ46419.1 - 0.047 14.0 2.6 0.053 13.9 0.2 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEZ46419.1 - 0.11 11.9 0.0 0.7 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 KEZ46420.1 - 8.4e-81 271.2 0.0 1.1e-80 270.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 KEZ46420.1 - 0.022 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RhoGAP PF00620.22 KEZ46423.1 - 9.3e-30 103.2 0.0 1.7e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain GVQW PF13900.1 KEZ46423.1 - 0.011 15.7 3.7 0.051 13.5 2.6 2.2 1 0 0 1 1 1 0 Putative binding domain Prenyltrans PF00432.16 KEZ46424.1 - 1.8e-59 196.8 8.7 6.1e-13 48.0 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KEZ46424.1 - 8.5e-37 126.0 0.0 4.2e-14 52.8 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KEZ46424.1 - 1.2e-11 44.5 0.0 9.1e-06 25.6 0.0 3.1 1 1 2 3 3 3 2 Prenyltransferase-like DUF2014 PF09427.5 KEZ46425.1 - 0.04 13.0 0.1 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) MutS_V PF00488.16 KEZ46426.1 - 5.7e-78 261.5 0.0 1.6e-77 260.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KEZ46426.1 - 2.4e-37 128.7 1.2 4.1e-37 127.9 0.8 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KEZ46426.1 - 5e-27 94.1 0.0 1e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KEZ46426.1 - 1e-09 38.5 0.0 1.1e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 KEZ46426.1 - 2.1e-08 34.1 0.0 5.6e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 KEZ46426.1 - 0.14 11.7 0.1 0.39 10.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAR1 PF03101.10 KEZ46427.1 - 0.00064 20.1 0.8 0.00064 20.1 0.6 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.6 KEZ46427.1 - 0.032 14.3 3.9 0.056 13.6 0.3 2.4 2 0 0 2 2 2 0 Transcription factor AFT MCM2_N PF12619.3 KEZ46427.1 - 0.11 12.4 8.8 0.22 11.4 6.1 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 TPPK_C PF12555.3 KEZ46427.1 - 0.11 12.2 0.1 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Pyr_redox_3 PF13738.1 KEZ46428.1 - 5.5e-14 52.7 0.0 1.2e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ46428.1 - 8.5e-13 48.3 0.0 1.1e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FMO-like PF00743.14 KEZ46428.1 - 2.2e-07 29.4 0.0 0.0017 16.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ46428.1 - 1.5e-06 28.1 0.2 1.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ46428.1 - 1.8e-05 23.8 0.0 0.025 13.4 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KEZ46428.1 - 5.3e-05 23.5 0.1 2.4 8.6 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KEZ46428.1 - 9.4e-05 22.3 0.0 0.00083 19.2 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KEZ46428.1 - 0.0004 19.5 0.0 0.58 9.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 KEZ46428.1 - 0.00087 18.2 0.1 0.012 14.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KEZ46428.1 - 0.0058 15.1 0.0 0.13 10.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KEZ46428.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KEZ46428.1 - 0.031 13.1 0.2 0.38 9.5 0.0 2.5 2 1 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KEZ46428.1 - 0.2 10.7 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Arginosuc_synth PF00764.14 KEZ46429.1 - 1.7e-140 468.4 0.0 2e-140 468.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KEZ46429.1 - 0.0016 17.7 0.0 0.0064 15.7 0.0 1.8 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KEZ46429.1 - 0.0065 15.9 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KEZ46429.1 - 0.11 11.0 0.0 0.23 9.9 0.0 1.5 2 0 0 2 2 2 0 tRNA methyl transferase DUF221 PF02714.10 KEZ46431.1 - 1.8e-90 303.1 17.0 1.8e-90 303.1 11.8 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEZ46431.1 - 1.8e-39 134.8 0.9 1.8e-39 134.8 0.6 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KEZ46431.1 - 1.9e-18 66.7 0.1 3.9e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) WD40 PF00400.27 KEZ46432.1 - 3e-82 267.8 29.2 5e-16 57.8 0.5 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KEZ46432.1 - 2e-05 24.4 0.0 0.023 14.3 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KEZ46432.1 - 0.00046 19.7 0.1 0.86 9.3 0.0 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat NLE PF08154.7 KEZ46432.1 - 0.00069 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KEZ46432.1 - 0.00078 17.6 7.2 0.1 10.6 0.1 4.5 2 2 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KEZ46432.1 - 0.0048 16.0 0.1 3.2 6.7 0.0 3.3 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 KEZ46432.1 - 0.053 12.8 0.1 19 4.6 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature 7TMR-DISM_7TM PF07695.6 KEZ46432.1 - 0.31 10.6 3.4 0.48 10.0 2.3 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Ank_2 PF12796.2 KEZ46433.1 - 9.8e-32 109.1 0.1 5e-18 65.2 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ46433.1 - 3.3e-21 73.2 2.4 0.0018 18.3 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.25 KEZ46433.1 - 5.2e-19 67.0 6.2 0.0019 17.9 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 KEZ46433.1 - 8.1e-18 64.0 1.1 0.011 15.9 0.0 6.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 KEZ46433.1 - 1.9e-16 60.0 0.0 7.5e-06 26.3 0.0 4.3 3 1 0 3 3 3 3 Ankyrin repeats (many copies) MutS_V PF00488.16 KEZ46435.1 - 5e-75 251.9 0.0 8.2e-75 251.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.13 KEZ46435.1 - 3.8e-07 30.1 1.0 5.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 MutS family domain IV MutS_III PF05192.13 KEZ46435.1 - 0.00084 19.1 0.4 0.0088 15.8 0.0 2.2 2 0 0 2 2 2 1 MutS domain III AAA_29 PF13555.1 KEZ46435.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GMC_oxred_N PF00732.14 KEZ46436.1 - 1.2e-29 103.4 0.0 1.1e-28 100.3 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ46436.1 - 9.3e-28 97.3 0.0 2e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KEZ46436.1 - 0.00035 20.5 0.0 0.00087 19.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ46436.1 - 0.00039 19.4 1.2 0.00092 18.2 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KEZ46436.1 - 0.0022 18.1 0.1 0.019 15.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KEZ46436.1 - 0.0051 15.7 1.2 0.0082 15.0 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KEZ46436.1 - 0.0054 15.6 0.0 0.0077 15.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KEZ46436.1 - 0.0079 16.0 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ46436.1 - 0.07 11.5 0.2 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KEZ46436.1 - 0.079 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 KEZ46436.1 - 0.14 11.1 0.4 0.22 10.5 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Tyrosinase PF00264.15 KEZ46437.1 - 7.4e-56 189.7 2.0 3.1e-55 187.7 0.1 2.2 2 0 0 2 2 2 1 Common central domain of tyrosinase WBS_methylT PF12589.3 KEZ46438.1 - 1.8e-17 63.6 4.7 3.4e-17 62.7 3.3 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KEZ46438.1 - 6.2e-11 42.6 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ46438.1 - 7.1e-07 29.5 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46438.1 - 6.6e-06 25.7 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46438.1 - 8.3e-05 23.1 0.0 0.00015 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KEZ46438.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KEZ46438.1 - 0.00027 20.7 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46438.1 - 0.00029 21.2 0.0 0.00088 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KEZ46438.1 - 0.003 17.5 0.0 0.0058 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KEZ46438.1 - 0.0074 15.4 0.0 0.071 12.1 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KEZ46438.1 - 0.0093 15.0 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 KEZ46438.1 - 0.04 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Erv26 PF04148.8 KEZ46439.1 - 8.5e-82 273.6 3.8 1.1e-81 273.2 2.6 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Dynamin_N PF00350.18 KEZ46440.1 - 3.3e-31 108.3 1.1 3.4e-29 101.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KEZ46440.1 - 1.5e-08 33.7 0.0 3.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KEZ46440.1 - 3.7e-05 23.6 0.0 0.00012 21.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KEZ46440.1 - 0.00092 19.6 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KEZ46440.1 - 0.025 14.8 1.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PAT1 PF09770.4 KEZ46440.1 - 0.52 8.5 33.0 0.73 8.0 22.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 KEZ46440.1 - 0.68 9.1 15.7 1.2 8.3 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) AUX_IAA PF02309.11 KEZ46440.1 - 2.2 7.9 8.2 5.7 6.6 5.7 1.7 1 0 0 1 1 1 0 AUX/IAA family AAA_23 PF13476.1 KEZ46440.1 - 4.9 7.4 0.0 4.9 7.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain Aminotran_4 PF01063.14 KEZ46441.1 - 1.5e-23 83.4 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Thioredoxin_7 PF13899.1 KEZ46442.1 - 1.2e-14 54.0 0.0 3.5e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 KEZ46442.1 - 2.1e-14 52.7 0.3 5.3e-14 51.4 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KEZ46442.1 - 3.5e-07 30.1 0.0 8.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 KEZ46442.1 - 0.014 15.0 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF255 RCSD PF05177.7 KEZ46442.1 - 0.37 11.3 5.6 0.47 10.9 1.7 2.3 2 0 0 2 2 2 0 RCSD region Pkinase PF00069.20 KEZ46443.1 - 1.5e-63 214.3 0.0 8e-33 113.6 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46443.1 - 2.1e-44 151.5 0.0 3.3e-24 85.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46443.1 - 0.08 11.8 0.0 0.77 8.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Ecm29 PF13001.2 KEZ46444.1 - 6.5e-113 377.8 0.0 1.6e-112 376.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 KEZ46444.1 - 4.6e-05 23.1 3.6 42 4.6 0.0 7.6 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.1 KEZ46444.1 - 0.0002 21.7 6.4 6 7.4 0.0 7.2 7 1 1 8 8 8 2 HEAT-like repeat MMS19_C PF12460.3 KEZ46444.1 - 0.97 8.0 1.4 6.2 5.4 0.0 3.0 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal adh_short PF00106.20 KEZ46445.1 - 1.7e-16 60.5 0.0 5.3e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KEZ46445.1 - 9.3e-06 25.4 0.1 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.14 KEZ46446.1 - 9e-13 47.9 1.0 4.1e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 KEZ46446.1 - 2.1e-06 26.8 0.1 3.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KEZ46446.1 - 4.7e-06 25.7 0.2 0.00052 19.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KEZ46446.1 - 5.9e-06 26.2 0.1 3e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ46446.1 - 3.4e-05 23.9 0.0 7.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KEZ46446.1 - 6.1e-05 23.3 0.4 0.015 15.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ46446.1 - 7.6e-05 21.3 0.1 0.0037 15.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KEZ46446.1 - 8.2e-05 22.5 1.0 0.00045 20.1 0.4 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KEZ46446.1 - 0.00055 19.1 0.1 0.0011 18.1 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KEZ46446.1 - 0.0012 17.7 0.2 0.0032 16.3 0.1 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KEZ46446.1 - 0.028 13.3 0.2 3.4 6.4 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Amino_oxidase PF01593.19 KEZ46446.1 - 0.043 12.8 0.1 8.6 5.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase p450 PF00067.17 KEZ46447.1 - 4.3e-61 206.8 0.0 5.8e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Iso_dh PF00180.15 KEZ46448.1 - 2e-81 273.6 0.0 2.3e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1157 PF06636.6 KEZ46448.1 - 0.097 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) CBS PF00571.23 KEZ46450.1 - 0.0024 17.6 0.0 0.095 12.5 0.0 2.5 2 1 0 2 2 2 2 CBS domain Mito_carr PF00153.22 KEZ46451.1 - 5e-51 170.3 5.5 7.1e-19 67.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Patatin PF01734.17 KEZ46452.1 - 5.7e-21 75.3 0.5 1.1e-20 74.3 0.3 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase zf-RING_5 PF14634.1 KEZ46452.1 - 0.0012 18.5 1.8 0.0026 17.4 1.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KEZ46452.1 - 0.0026 17.7 3.5 0.0075 16.2 2.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KEZ46452.1 - 0.015 15.1 3.5 0.042 13.6 2.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 KEZ46452.1 - 0.097 12.3 2.5 0.23 11.1 1.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 KEZ46453.1 - 1.1e-49 169.0 0.0 1.1e-49 169.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KEZ46453.1 - 1.5e-23 83.7 0.0 2.8e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2229 PF09989.4 KEZ46453.1 - 0.085 12.3 0.6 0.17 11.2 0.4 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) hDGE_amylase PF14701.1 KEZ46453.1 - 0.12 11.2 2.2 0.22 10.3 1.5 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF106 PF01956.11 KEZ46453.1 - 0.26 10.7 4.2 0.51 9.8 2.9 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Borrelia_P83 PF05262.6 KEZ46453.1 - 1.8 6.7 12.2 2.7 6.1 8.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_transf_22 PF03901.12 KEZ46454.1 - 5.7e-42 144.1 15.6 7.2e-42 143.8 10.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 KEZ46454.1 - 0.00035 20.5 13.7 0.00035 20.5 9.5 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PP2C PF00481.16 KEZ46455.1 - 3.5e-53 180.6 0.0 5.4e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KEZ46455.1 - 1.1e-49 165.3 58.2 2.8e-07 29.9 0.1 12.6 9 3 2 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ46455.1 - 1.2e-36 124.2 61.0 9.9e-10 38.0 0.2 9.9 4 3 9 13 13 13 11 Leucine rich repeat Guanylate_cyc PF00211.15 KEZ46455.1 - 2.6e-31 108.3 0.1 7.5e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KEZ46455.1 - 8e-20 67.8 61.7 0.27 11.4 0.0 19.8 17 2 3 20 20 20 6 Leucine Rich Repeat LRR_7 PF13504.1 KEZ46455.1 - 5.9e-12 43.7 46.1 0.46 10.8 0.1 17.1 18 0 0 18 18 17 2 Leucine rich repeat Ad_cyc_g-alpha PF08509.6 KEZ46455.1 - 7.6e-11 41.1 0.4 2.2e-10 39.7 0.3 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 KEZ46455.1 - 7.3e-08 32.8 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.1 KEZ46455.1 - 0.00013 21.6 18.3 0.44 10.0 0.8 4.4 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 KEZ46455.1 - 0.017 15.0 54.9 1.9 8.7 0.0 15.9 17 1 1 18 18 18 0 Leucine Rich repeat LRR_5 PF13306.1 KEZ46455.1 - 0.15 11.7 1.8 1.3 8.6 0.1 2.9 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) LRR_3 PF07725.7 KEZ46455.1 - 3.4 7.6 6.0 39 4.2 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.20 KEZ46456.1 - 2.1e-23 82.7 0.0 5e-23 81.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46456.1 - 0.00015 20.9 0.0 0.012 14.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RTC4 PF14474.1 KEZ46457.1 - 3.1e-30 104.6 0.0 5.9e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.9 KEZ46458.1 - 8.6e-30 103.8 12.8 4.1e-15 55.4 0.2 3.3 1 1 1 2 2 2 2 Dynamitin FH2 PF02181.18 KEZ46458.1 - 0.001 18.0 3.0 0.55 9.0 0.0 2.9 3 0 0 3 3 3 2 Formin Homology 2 Domain Baculo_PEP_C PF04513.7 KEZ46458.1 - 0.0034 17.2 4.5 0.031 14.1 0.2 3.1 3 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.9 KEZ46458.1 - 0.013 15.1 6.0 0.41 10.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 KEZ46458.1 - 0.024 14.2 12.0 0.082 12.4 0.3 3.3 2 1 1 3 3 3 0 IncA protein DUF2408 PF10303.4 KEZ46458.1 - 0.031 14.3 4.2 0.68 10.0 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Phage_int_SAM_2 PF12834.2 KEZ46458.1 - 0.053 13.9 0.3 0.15 12.4 0.2 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal TMF_DNA_bd PF12329.3 KEZ46458.1 - 0.26 11.1 10.9 2.4 8.0 1.7 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 KEZ46458.1 - 0.41 10.3 9.3 0.6 9.8 0.3 3.7 2 1 2 4 4 4 0 Laminin Domain II IFT57 PF10498.4 KEZ46458.1 - 0.52 8.9 5.8 0.19 10.4 0.1 2.5 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.4 KEZ46458.1 - 0.58 10.3 8.2 4.4 7.5 0.2 4.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.6 KEZ46458.1 - 0.77 9.1 8.0 0.48 9.8 0.1 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 DivIC PF04977.10 KEZ46458.1 - 1.2 8.6 16.8 0.21 11.0 0.4 3.6 3 1 1 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.7 KEZ46458.1 - 1.7 8.3 16.6 0.65 9.7 1.6 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein GrpE PF01025.14 KEZ46458.1 - 2.6 7.5 11.7 0.28 10.7 1.0 3.2 2 1 0 3 3 3 0 GrpE Hep_59 PF07052.6 KEZ46458.1 - 3.4 8.0 10.4 1.7 9.0 2.7 2.9 2 1 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 APG6 PF04111.7 KEZ46458.1 - 4.7 6.1 12.2 3.1 6.7 0.7 2.5 2 1 0 2 2 2 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 KEZ46458.1 - 8.2 6.2 14.2 4.1 7.2 0.8 3.5 3 1 1 4 4 4 0 Prefoldin subunit DUF972 PF06156.8 KEZ46458.1 - 8.3 6.8 10.5 5.7 7.3 0.3 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF972) Ribosomal_S28e PF01200.13 KEZ46459.1 - 6.6e-19 67.4 0.8 9.9e-19 66.8 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S28e ThiS PF02597.15 KEZ46459.1 - 1.9e-08 34.5 0.0 3.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 ThiS family Complex1_LYR PF05347.10 KEZ46460.1 - 3.4e-16 58.7 0.7 4.2e-16 58.4 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KEZ46460.1 - 9.6e-13 48.1 0.5 1.1e-12 47.8 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Glyco_transf_34 PF05637.7 KEZ46462.1 - 1.6e-65 220.9 0.4 2e-65 220.6 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pyr_redox_3 PF13738.1 KEZ46463.1 - 1.9e-21 77.0 0.0 1.7e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ46463.1 - 6.1e-11 41.2 0.0 4.4e-09 35.0 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ46463.1 - 9.6e-09 35.1 0.0 2.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KEZ46463.1 - 0.00017 21.3 0.1 0.37 10.5 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KEZ46463.1 - 0.00032 19.7 0.0 0.13 11.1 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KEZ46463.1 - 0.016 15.0 0.0 5.3 6.8 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AP2 PF00847.15 KEZ46463.1 - 0.047 13.8 0.7 0.047 13.8 0.5 1.8 2 0 0 2 2 2 0 AP2 domain Methyltransf_16 PF10294.4 KEZ46464.1 - 0.0043 16.5 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase GPI-anchored PF10342.4 KEZ46465.1 - 6.7e-18 64.9 0.4 6.7e-18 64.9 0.3 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1517 PF07466.6 KEZ46465.1 - 0.0065 15.4 1.5 0.0097 14.9 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) RAP1 PF07218.6 KEZ46465.1 - 0.039 12.0 13.6 0.043 11.9 9.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pex14_N PF04695.8 KEZ46465.1 - 0.11 12.5 4.4 0.22 11.5 3.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 KEZ46465.1 - 1.1 7.0 13.9 1.1 7.0 9.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 KEZ46465.1 - 2.3 6.4 7.4 2.7 6.1 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Fer2_3 PF13085.1 KEZ46466.1 - 1.1e-31 108.9 0.0 1.7e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KEZ46466.1 - 2.6e-09 37.2 6.7 2.6e-09 37.2 4.6 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KEZ46466.1 - 4.5e-09 36.2 4.9 4.5e-09 36.2 3.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KEZ46466.1 - 6.6e-06 26.4 7.7 2.6e-05 24.5 1.6 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KEZ46466.1 - 8.6e-05 22.2 4.7 8.6e-05 22.2 3.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KEZ46466.1 - 0.0013 18.4 0.4 0.0013 18.4 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 KEZ46466.1 - 0.0035 17.5 9.4 0.089 13.0 0.5 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 KEZ46466.1 - 3.4 8.1 17.0 2 8.8 7.9 2.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Epimerase PF01370.16 KEZ46467.1 - 3.1e-19 69.3 0.0 4.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KEZ46467.1 - 1.2e-08 34.1 0.0 2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KEZ46467.1 - 0.00076 19.5 0.1 0.0075 16.2 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KEZ46467.1 - 0.012 15.5 0.0 0.035 14.0 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KEZ46467.1 - 0.013 14.1 0.0 0.032 12.9 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KEZ46467.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 KEZ46467.1 - 0.17 11.7 0.1 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain F_actin_cap_B PF01115.12 KEZ46468.1 - 1.5e-107 358.2 0.0 1.8e-107 358.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit P3A PF08727.6 KEZ46468.1 - 0.036 13.3 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like BAH PF01426.13 KEZ46469.1 - 7e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KEZ46469.1 - 0.0026 17.4 3.8 0.006 16.2 2.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 KEZ46469.1 - 0.0061 16.5 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 RING-like domain FANCL_C PF11793.3 KEZ46469.1 - 0.051 13.5 1.1 0.12 12.3 0.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain ATG22 PF11700.3 KEZ46470.1 - 7.6e-194 644.6 10.4 8.6e-194 644.4 7.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Cg6151-P PF10233.4 KEZ46471.1 - 2.9e-34 117.4 13.8 3.5e-34 117.1 9.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF1430 PF07242.6 KEZ46471.1 - 1.5 8.9 9.1 0.7 9.9 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Cytochrom_B558a PF05038.8 KEZ46471.1 - 9.6 5.7 8.0 29 4.2 5.3 1.9 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF3210 PF11489.3 KEZ46472.1 - 2.8e-82 277.5 111.6 5e-82 276.7 60.9 3.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3210) Ribosomal_S17e PF00833.13 KEZ46472.1 - 0.024 14.3 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal S17 Dna2 PF08696.6 KEZ46473.1 - 3.4e-72 242.1 0.0 7.3e-72 241.0 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KEZ46473.1 - 1.6e-52 177.7 0.0 2.6e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ46473.1 - 1.4e-40 139.3 0.2 7e-20 71.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KEZ46473.1 - 4.1e-13 49.3 0.0 1.8e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ46473.1 - 2.8e-11 43.0 0.3 8.5e-11 41.4 0.1 1.9 2 0 0 2 2 1 1 Part of AAA domain Cas_Cas4 PF01930.12 KEZ46473.1 - 2e-09 37.5 0.0 1.5e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 KEZ46473.1 - 7.2e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KEZ46473.1 - 1.2e-06 28.2 0.6 0.58 9.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KEZ46473.1 - 0.00052 20.0 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 KEZ46473.1 - 0.00057 19.5 0.0 0.0016 18.1 0.0 1.8 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KEZ46473.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 KEZ46473.1 - 0.0021 17.5 0.2 0.0048 16.3 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.9 KEZ46473.1 - 0.0028 16.6 0.0 0.087 11.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase MobB PF03205.9 KEZ46473.1 - 0.0029 17.3 0.1 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KEZ46473.1 - 0.0038 16.6 0.0 0.0097 15.3 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KEZ46473.1 - 0.035 13.5 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KEZ46473.1 - 0.066 13.0 0.2 0.23 11.2 0.1 1.9 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_22 PF13401.1 KEZ46473.1 - 0.072 13.2 0.1 0.42 10.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KEZ46473.1 - 0.12 11.7 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase PEPCK_ATP PF01293.15 KEZ46473.1 - 0.15 10.5 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF2422 PF10337.4 KEZ46474.1 - 1.6e-11 43.7 11.7 6.5e-09 35.0 0.5 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KEZ46474.1 - 0.03 13.9 0.0 0.22 11.1 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2421) ESSS PF10183.4 KEZ46475.1 - 2.3e-23 82.6 0.0 2.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.14 KEZ46476.1 - 1.9e-33 115.8 0.0 2.7e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV CVNH PF08881.5 KEZ46477.1 - 3.5e-10 40.0 0.0 5.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 CVNH domain Pkinase PF00069.20 KEZ46478.1 - 8.7e-17 61.1 0.0 2.2e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46478.1 - 9.4e-10 37.9 0.0 4.7e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1515 PF07439.6 KEZ46478.1 - 0.031 14.0 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Tyrosinase PF00264.15 KEZ46479.1 - 5.9e-34 118.1 0.0 1.2e-33 117.1 0.0 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.13 KEZ46480.1 - 8.5e-26 90.3 0.0 1.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46480.1 - 0.00034 20.4 6.8 0.00059 19.7 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-primase PF09329.6 KEZ46481.1 - 6.3e-18 64.1 1.3 1.1e-17 63.2 0.9 1.5 1 0 0 1 1 1 1 Primase zinc finger IRK PF01007.15 KEZ46481.1 - 0.28 9.9 0.1 0.46 9.2 0.1 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel DASH_Duo1 PF08651.5 KEZ46482.1 - 1.6e-29 101.2 0.1 2.2e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.9 KEZ46482.1 - 0.094 11.5 1.7 0.12 11.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Radial_spoke_3 PF06098.6 KEZ46482.1 - 2.4 7.0 8.7 4.2 6.3 6.0 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 TTL PF03133.10 KEZ46484.1 - 4.3e-55 186.7 0.0 7.2e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 KEZ46484.1 - 6.2e-45 152.9 0.0 1e-44 152.1 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 KEZ46484.1 - 0.0016 18.2 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 KEZ46484.1 - 0.0025 16.6 0.0 0.019 13.7 0.0 2.2 3 0 0 3 3 3 1 YheC/D like ATP-grasp E1-E2_ATPase PF00122.15 KEZ46485.1 - 3.6e-57 193.0 1.4 3.6e-57 193.0 1.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KEZ46485.1 - 1.5e-39 135.3 4.8 1.5e-39 135.3 3.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KEZ46485.1 - 7.8e-29 101.6 0.0 5.7e-28 98.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KEZ46485.1 - 3.7e-18 65.2 0.0 7.5e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KEZ46485.1 - 6e-17 62.4 0.0 1.4e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KEZ46485.1 - 3.4e-05 23.5 1.1 8.7e-05 22.2 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KEZ46485.1 - 0.00033 20.0 0.2 0.0019 17.5 0.0 2.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Sulfate_tra_GLY PF13792.1 KEZ46485.1 - 0.034 13.7 1.2 0.42 10.3 0.0 3.1 3 0 0 3 3 3 0 Sulfate transporter N-terminal domain with GLY motif SIR2 PF02146.12 KEZ46486.1 - 7.2e-57 191.9 0.0 1.1e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KEZ46486.1 - 0.037 13.5 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) SR-25 PF10500.4 KEZ46486.1 - 2.4 7.5 26.7 0.029 13.8 11.8 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FAM220 PF15487.1 KEZ46486.1 - 6.1 6.1 13.0 9.8 5.4 9.0 1.3 1 0 0 1 1 1 0 FAM220 family NARP1 PF12569.3 KEZ46486.1 - 6.4 5.3 5.7 9.2 4.8 4.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TT_ORF2 PF02957.10 KEZ46486.1 - 7.3 7.3 8.5 1.4 9.6 2.3 2.2 2 0 0 2 2 2 0 TT viral ORF2 CytochromB561_N PF09786.4 KEZ46486.1 - 8 4.7 11.8 11 4.2 8.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Spermine_synth PF01564.12 KEZ46488.1 - 8.3e-09 34.7 0.0 1.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KEZ46488.1 - 3.4e-06 27.0 0.0 7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ46488.1 - 0.00014 21.5 0.0 0.0016 18.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46488.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46488.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46488.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RCC1 PF00415.13 KEZ46490.1 - 7.3e-48 160.5 19.6 6e-09 35.9 0.3 8.1 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KEZ46490.1 - 5e-32 108.8 32.7 9.5e-10 37.8 0.7 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KEZ46490.1 - 0.046 13.1 1.5 14 5.2 0.0 4.1 4 0 0 4 4 4 0 Putative carbohydrate binding domain Stm1_N PF09598.5 KEZ46490.1 - 0.82 10.4 5.6 2.2 9.0 3.9 1.7 1 0 0 1 1 1 0 Stm1 NAD_binding_2 PF03446.10 KEZ46491.1 - 1.2e-30 106.4 0.1 2e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KEZ46491.1 - 1.6e-11 44.4 0.3 1e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KEZ46491.1 - 5e-09 36.2 0.1 1.1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KEZ46491.1 - 9e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KEZ46491.1 - 0.00023 21.1 0.1 0.00064 19.6 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KEZ46491.1 - 0.0059 15.6 0.1 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 KEZ46491.1 - 0.014 15.9 0.2 0.064 13.7 0.0 2.1 2 1 1 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KEZ46491.1 - 0.046 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_dim PF02852.17 KEZ46491.1 - 0.18 11.8 1.5 10 6.1 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain ATP_synt_H PF05493.8 KEZ46492.1 - 1.8e-22 79.1 3.6 2e-22 78.9 2.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 KEZ46492.1 - 0.058 13.2 0.5 0.09 12.6 0.1 1.5 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix YndJ PF14158.1 KEZ46492.1 - 0.12 11.4 3.3 0.13 11.2 2.3 1.0 1 0 0 1 1 1 0 YndJ-like protein OppC_N PF12911.2 KEZ46492.1 - 0.15 11.4 0.4 6.9 6.1 0.2 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3112 PF11309.3 KEZ46492.1 - 0.24 11.1 2.1 0.25 11.1 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Rab5ip PF07019.7 KEZ46492.1 - 0.29 11.2 2.4 0.33 11.0 1.7 1.1 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Fig1 PF12351.3 KEZ46492.1 - 0.39 10.5 4.6 0.42 10.4 3.2 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.8 KEZ46492.1 - 0.6 8.9 3.2 0.64 8.8 2.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4131 PF13567.1 KEZ46492.1 - 1 8.7 4.4 1.1 8.6 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ABC2_membrane_4 PF12730.2 KEZ46492.1 - 1.3 8.1 4.6 1.7 7.7 3.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1049 PF06305.6 KEZ46492.1 - 1.4 8.4 4.1 4.2 6.9 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Arv1 PF04161.8 KEZ46493.1 - 3.7e-47 160.9 0.0 4.8e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family Fungal_trans PF04082.13 KEZ46494.1 - 9.2e-37 126.3 0.0 1.5e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PigN PF04987.9 KEZ46495.1 - 7.8e-158 525.7 29.0 1.1e-157 525.2 20.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KEZ46495.1 - 1.1e-11 44.7 0.6 6.9e-10 38.7 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KEZ46495.1 - 9.1e-08 31.6 0.1 1.4e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KEZ46495.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Csm1 PF12539.3 KEZ46496.1 - 1.6e-27 95.8 0.0 2.9e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TMF_DNA_bd PF12329.3 KEZ46496.1 - 1.1e-05 25.1 4.5 1.1e-05 25.1 3.1 2.6 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding Filament PF00038.16 KEZ46496.1 - 0.0007 19.1 5.0 0.0012 18.4 3.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein Phlebovirus_NSM PF07246.6 KEZ46496.1 - 0.01 15.0 4.8 0.014 14.5 3.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M UPF0242 PF06785.6 KEZ46496.1 - 0.022 13.4 1.4 0.033 12.8 1.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Reo_sigmaC PF04582.7 KEZ46496.1 - 0.025 13.7 5.6 0.054 12.6 3.4 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KEZ46496.1 - 0.04 12.3 6.1 0.056 11.9 4.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KEZ46496.1 - 0.2 8.9 11.0 0.27 8.4 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KEZ46496.1 - 0.21 11.1 10.5 0.39 10.2 6.6 1.7 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 KEZ46496.1 - 0.3 10.9 10.5 0.82 9.5 7.0 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 KEZ46496.1 - 0.57 8.5 2.5 0.81 8.0 1.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.8 KEZ46496.1 - 0.84 9.6 9.9 1 9.4 2.2 2.4 2 0 0 2 2 2 0 DivIVA protein Fib_alpha PF08702.5 KEZ46496.1 - 1.1 9.3 4.4 3.1 7.9 3.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 KEZ46496.1 - 1.2 9.0 4.9 5.2 7.0 2.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 KEZ46496.1 - 2.3 7.1 9.4 3.7 6.5 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC37_N PF03234.9 KEZ46496.1 - 2.7 8.2 8.5 4.3 7.6 4.2 2.1 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Fmp27_WPPW PF10359.4 KEZ46496.1 - 3.3 6.0 8.6 4 5.7 5.2 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 KEZ46496.1 - 3.5 8.0 8.1 0.94 9.8 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 KEZ46496.1 - 9.8 5.0 10.9 23 3.7 7.6 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA PF00004.24 KEZ46497.1 - 8e-38 129.6 0.0 1.2e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ46497.1 - 8.6e-07 29.1 0.8 0.00019 21.4 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KEZ46497.1 - 2e-06 28.0 0.1 0.00038 20.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KEZ46497.1 - 2.3e-06 26.8 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KEZ46497.1 - 2.3e-06 28.4 0.0 7.8e-06 26.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KEZ46497.1 - 4e-06 26.7 0.0 7.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KEZ46497.1 - 7.3e-06 26.0 0.0 1.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KEZ46497.1 - 7.5e-06 25.7 0.2 4.9e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KEZ46497.1 - 0.00012 22.0 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEZ46497.1 - 0.00013 21.4 1.2 0.038 13.3 0.1 2.6 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KEZ46497.1 - 0.00016 21.1 0.3 0.00033 20.1 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KEZ46497.1 - 0.00058 20.1 0.1 0.0025 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KEZ46497.1 - 0.00069 18.8 0.1 0.0017 17.5 0.1 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KEZ46497.1 - 0.00072 18.7 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 KEZ46497.1 - 0.00086 19.0 0.0 0.0086 15.7 0.0 2.2 1 1 1 2 2 2 1 NACHT domain RNA_helicase PF00910.17 KEZ46497.1 - 0.0011 19.0 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 KEZ46497.1 - 0.0018 18.2 0.2 0.0052 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KEZ46497.1 - 0.0035 17.4 0.0 0.0084 16.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 KEZ46497.1 - 0.0052 16.3 0.1 0.014 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ46497.1 - 0.0057 16.3 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 KEZ46497.1 - 0.012 14.3 0.0 0.02 13.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 KEZ46497.1 - 0.012 15.0 0.1 0.052 13.0 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KEZ46497.1 - 0.022 14.4 0.1 0.2 11.3 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 KEZ46497.1 - 0.023 14.9 0.0 0.043 14.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter SKI PF01202.17 KEZ46497.1 - 0.025 14.4 0.1 0.098 12.5 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase DUF815 PF05673.8 KEZ46497.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 KEZ46497.1 - 0.043 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KEZ46497.1 - 0.05 13.0 0.5 1.4 8.2 0.0 3.0 2 1 0 3 3 3 0 AAA-like domain TIP49 PF06068.8 KEZ46497.1 - 0.05 12.3 0.0 0.082 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus NB-ARC PF00931.17 KEZ46497.1 - 0.058 12.2 0.0 0.34 9.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 KEZ46497.1 - 0.075 12.1 0.0 0.48 9.4 0.0 2.0 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 KEZ46497.1 - 0.081 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Guanylate_kin PF00625.16 KEZ46497.1 - 0.085 12.2 0.0 3.5 7.0 0.0 2.9 2 1 1 3 3 3 0 Guanylate kinase AAA_3 PF07726.6 KEZ46497.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KEZ46497.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.9 KEZ46497.1 - 0.17 10.8 0.1 2 7.3 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Cys_Met_Meta_PP PF01053.15 KEZ46498.1 - 3.9e-140 466.5 0.0 4.5e-140 466.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KEZ46498.1 - 5.3e-07 28.7 0.0 1.6e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KEZ46498.1 - 1.2e-06 27.7 0.0 1.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KEZ46498.1 - 5.2e-06 25.7 0.4 8.9e-06 24.9 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 KEZ46498.1 - 0.00035 18.9 0.1 0.0011 17.4 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 KEZ46498.1 - 0.00071 18.8 0.3 0.0017 17.5 0.2 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 KEZ46498.1 - 0.00074 18.3 0.0 0.0024 16.6 0.0 1.8 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase POTRA_2 PF08479.6 KEZ46498.1 - 0.064 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type MFS_1 PF07690.11 KEZ46499.1 - 3e-16 59.0 12.6 3e-16 59.0 8.8 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KEZ46499.1 - 6.9e-14 51.7 2.8 6.9e-14 51.7 2.0 1.7 2 0 0 2 2 2 1 Nodulin-like PGAP1 PF07819.8 KEZ46500.1 - 1.9e-89 299.1 0.0 2.7e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEZ46500.1 - 4.2e-06 26.5 0.0 1.2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ46500.1 - 7e-05 22.8 0.1 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ46500.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 KEZ46500.1 - 0.032 13.5 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 KEZ46500.1 - 0.072 11.7 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family LCAT PF02450.10 KEZ46500.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MutL_C PF08676.6 KEZ46501.1 - 5.6e-22 77.8 0.0 1.5e-21 76.5 0.0 1.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KEZ46501.1 - 6.8e-18 64.2 0.0 1.7e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KEZ46501.1 - 1.1e-11 44.5 0.1 2.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEZ46501.1 - 3.6e-11 42.7 0.0 8.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.9 KEZ46503.1 - 8.3e-05 22.5 0.0 0.00064 19.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ46503.1 - 0.0036 17.3 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KEZ46503.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding ETF PF01012.16 KEZ46504.1 - 6.6e-41 139.7 0.6 1.2e-40 138.9 0.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KEZ46504.1 - 2.8e-36 122.9 0.3 2.8e-36 122.9 0.2 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.12 KEZ46505.1 - 1.1e-35 121.6 0.1 2.2e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KEZ46505.1 - 2.2e-09 37.2 0.2 9e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KEZ46505.1 - 2.5e-08 33.8 0.1 1.6e-07 31.2 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF3439 PF11921.3 KEZ46505.1 - 0.23 11.2 9.6 0.23 11.1 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ZZ PF00569.12 KEZ46505.1 - 1.2 8.6 6.2 2.8 7.5 4.3 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type Carn_acyltransf PF00755.15 KEZ46506.1 - 2.6e-170 567.4 0.0 3e-170 567.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.14 KEZ46507.1 - 3.8e-95 318.7 2.1 5.2e-95 318.3 1.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KEZ46507.1 - 2.3e-53 179.8 1.6 3.1e-53 179.3 1.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DUF2774 PF11242.3 KEZ46507.1 - 0.039 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) PfkB PF00294.19 KEZ46508.1 - 6.6e-14 51.7 0.0 1.9e-08 33.8 0.0 2.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.18 KEZ46509.1 - 3.6e-129 430.2 0.1 5.7e-129 429.6 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KEZ46509.1 - 2.3e-07 31.3 0.0 2.7e-06 27.8 0.0 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KEZ46509.1 - 2.5e-07 30.0 0.0 3e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KEZ46509.1 - 0.002 17.7 0.0 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KEZ46509.1 - 0.0068 15.8 0.0 0.026 14.0 0.0 1.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_5 PF07728.9 KEZ46509.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIIF_alpha PF05793.7 KEZ46509.1 - 0.075 11.3 7.5 0.11 10.8 5.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Exo70 PF03081.10 KEZ46510.1 - 8.2e-70 235.4 0.0 1.5e-69 234.6 0.0 1.4 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Apolipoprotein PF01442.13 KEZ46510.1 - 0.17 11.3 2.9 0.37 10.2 0.2 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Syja_N PF02383.13 KEZ46511.1 - 1.2e-74 251.0 0.0 4.8e-40 137.2 0.0 2.5 2 1 1 3 3 3 2 SacI homology domain Tox-ODYAM1 PF15642.1 KEZ46511.1 - 0.048 12.3 0.0 0.082 11.5 0.0 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus PolyA_pol PF01743.15 KEZ46512.1 - 2.7e-26 92.2 0.0 6.4e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KEZ46512.1 - 1.5e-06 27.6 0.0 3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KEZ46512.1 - 0.00086 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Suf PF05843.9 KEZ46513.1 - 3e-10 40.2 5.1 0.1 12.3 0.0 5.9 4 1 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_12 PF13424.1 KEZ46513.1 - 2e-09 37.2 0.8 0.28 11.1 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ46513.1 - 1.4e-05 24.2 6.4 0.00025 20.1 0.6 3.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ46513.1 - 2.2e-05 24.6 19.6 29 5.6 0.0 11.2 11 5 4 15 15 14 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KEZ46513.1 - 3.1e-05 23.0 10.2 0.016 14.0 0.0 6.0 2 2 3 6 6 6 2 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 KEZ46513.1 - 6.6e-05 22.4 1.5 1.8 8.2 0.0 6.0 7 0 0 7 7 7 1 TPR repeat Mad3_BUB1_I PF08311.7 KEZ46513.1 - 0.00018 21.3 5.9 0.84 9.4 0.1 5.8 6 1 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.1 KEZ46513.1 - 0.0002 21.9 9.1 0.41 11.3 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46513.1 - 0.00053 20.2 0.0 2.6 8.4 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.4 KEZ46513.1 - 0.0086 15.4 0.0 0.27 10.6 0.0 2.5 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 KEZ46513.1 - 0.01 15.5 2.1 5.5 7.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ46513.1 - 0.019 15.1 1.0 2.1 8.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46513.1 - 0.52 10.3 17.2 37 4.5 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat HAT PF02184.11 KEZ46513.1 - 1.9 8.2 15.1 2.3 8.0 0.0 6.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.1 KEZ46513.1 - 2.1 8.9 5.9 25 5.6 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 KEZ46514.1 - 1.1e-22 80.5 4.1 4.2e-17 62.3 0.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit D Viral_P18 PF04521.8 KEZ46514.1 - 0.13 11.6 2.9 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein RRM_1 PF00076.17 KEZ46515.1 - 1.7e-24 85.2 0.5 2e-11 43.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ46515.1 - 3.8e-17 62.0 0.1 1.5e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ46515.1 - 9.8e-13 47.7 0.0 2.3e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3227 PF11537.3 KEZ46515.1 - 0.022 14.8 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Sec7 PF01369.15 KEZ46516.1 - 2.5e-62 209.9 0.0 4.2e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KEZ46516.1 - 1e-16 60.8 1.8 8e-10 38.4 0.2 3.3 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 KEZ46517.1 - 1.3e-119 398.3 2.1 2.5e-119 397.3 0.0 2.0 2 0 0 2 2 2 1 Anp1 RNA_pol_Rpb8 PF03870.10 KEZ46519.1 - 1.5e-34 119.1 0.0 1.7e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 GDA1_CD39 PF01150.12 KEZ46520.1 - 5.7e-101 338.1 0.0 7.1e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RNase_H2_suC PF08615.6 KEZ46521.1 - 0.037 13.8 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LVIVD PF08309.6 KEZ46522.1 - 1.4e-11 43.2 0.0 0.0028 16.6 0.0 4.8 4 0 0 4 4 4 4 LVIVD repeat DLH PF01738.13 KEZ46523.1 - 7.4e-19 67.8 0.0 7.2e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ46523.1 - 2.9e-05 23.8 0.0 3.5e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ46523.1 - 0.0096 15.8 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family SGL PF08450.7 KEZ46524.1 - 6e-32 110.9 0.1 9.1e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 KEZ46524.1 - 0.0032 17.3 1.1 11 6.1 0.0 4.0 4 0 0 4 4 4 2 NHL repeat Str_synth PF03088.11 KEZ46524.1 - 0.028 14.4 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Reg_prop PF07494.6 KEZ46524.1 - 0.1 12.6 0.7 52 4.3 0.0 4.3 6 0 0 6 6 6 0 Two component regulator propeller Ribosomal_L19e PF01280.15 KEZ46525.1 - 0.81 9.4 9.0 1.4 8.6 6.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L19e Methyltransf_23 PF13489.1 KEZ46526.1 - 1.7e-19 70.1 0.0 2.5e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46526.1 - 3.7e-10 39.5 0.0 2.3e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46526.1 - 4.6e-10 39.8 0.0 9.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46526.1 - 1e-09 38.9 0.1 1.3e-08 35.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46526.1 - 4.4e-09 36.7 0.0 3.9e-08 33.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KEZ46526.1 - 1.5e-06 27.4 0.0 3.4e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ46526.1 - 2.2e-05 24.7 0.0 4.9e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ46526.1 - 0.00018 21.5 0.1 0.0005 20.1 0.0 1.5 1 1 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KEZ46526.1 - 0.00034 19.8 0.0 0.0031 16.6 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KEZ46526.1 - 0.00045 19.6 0.0 0.00091 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ46526.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 KEZ46526.1 - 0.0092 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 KEZ46526.1 - 0.039 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0146 PF03686.8 KEZ46526.1 - 0.043 13.6 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0146) CMAS PF02353.15 KEZ46526.1 - 0.051 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 KEZ46526.1 - 0.14 10.8 0.0 0.24 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.8 KEZ46526.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 KEZ46526.1 - 0.17 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cu-oxidase_2 PF07731.9 KEZ46527.1 - 3.6e-43 146.3 9.0 3.1e-39 133.6 2.7 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KEZ46527.1 - 7.1e-43 145.0 2.3 7.8e-38 128.8 0.1 3.4 2 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KEZ46527.1 - 7.5e-40 136.4 0.7 1.3e-34 119.4 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KEZ46527.1 - 0.00024 20.9 0.0 6.1 6.7 0.0 3.8 3 1 0 3 3 3 2 Cupredoxin-like domain FTR1 PF03239.9 KEZ46528.1 - 1e-58 198.6 7.1 4.4e-32 111.2 0.1 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF3169 PF11368.3 KEZ46528.1 - 0.001 18.3 1.3 0.0031 16.7 0.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3169) zf-DHHC PF01529.15 KEZ46528.1 - 4.1 6.7 4.8 9.8 5.5 0.3 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase Hydrophobin PF01185.13 KEZ46529.1 - 2.8e-10 40.4 8.6 5.4e-10 39.5 5.9 1.5 1 1 0 1 1 1 1 Fungal hydrophobin GMC_oxred_N PF00732.14 KEZ46530.1 - 6.9e-61 205.9 0.0 8.7e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ46530.1 - 1.2e-33 116.3 0.0 2.3e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KEZ46530.1 - 0.0039 17.1 1.6 0.011 15.7 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KEZ46530.1 - 0.0073 15.2 0.1 0.037 12.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KEZ46530.1 - 0.011 14.6 0.0 0.095 11.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KEZ46530.1 - 0.044 12.6 0.1 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4484 PF14831.1 KEZ46530.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Transp_cyt_pur PF02133.10 KEZ46531.1 - 4.5e-147 490.1 35.2 5.2e-147 489.9 24.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.14 KEZ46532.1 - 4.2e-50 169.3 0.0 7.2e-50 168.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEZ46532.1 - 5.5e-15 54.9 0.0 7.1e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEZ46532.1 - 0.00016 21.5 0.0 0.00047 20.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KEZ46532.1 - 0.037 13.4 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 KEZ46532.1 - 0.071 13.2 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KEZ46532.1 - 0.091 13.2 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold FTR1 PF03239.9 KEZ46533.1 - 7e-48 163.1 4.2 7.9e-48 162.9 2.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 KEZ46533.1 - 0.00093 19.1 0.3 0.00093 19.1 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4231) DUF401 PF04165.7 KEZ46533.1 - 0.075 12.0 3.8 0.02 13.9 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF401) DUF202 PF02656.10 KEZ46533.1 - 0.083 13.1 1.9 0.37 11.0 0.0 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Vma12 PF11712.3 KEZ46533.1 - 2.5 7.8 4.9 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cu-oxidase_3 PF07732.10 KEZ46534.1 - 4e-46 155.5 6.0 4.3e-42 142.5 1.4 4.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEZ46534.1 - 7e-40 135.7 9.7 8.8e-37 125.6 0.1 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KEZ46534.1 - 1.5e-38 132.1 0.1 1.2e-34 119.5 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KEZ46534.1 - 0.0012 18.7 0.0 5.8 6.8 0.0 4.0 4 0 0 4 4 4 1 Cupredoxin-like domain TauD PF02668.11 KEZ46535.1 - 1.8e-49 168.7 0.1 2.4e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ketoacyl-synt PF00109.21 KEZ46536.1 - 4.3e-74 249.1 0.0 8.8e-74 248.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KEZ46536.1 - 3e-64 217.3 0.0 4.9e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 KEZ46536.1 - 2.7e-62 209.6 1.5 8.8e-62 207.9 0.6 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KEZ46536.1 - 5.3e-51 172.8 1.7 1.2e-50 171.6 0.1 2.6 3 0 0 3 3 1 1 short chain dehydrogenase PS-DH PF14765.1 KEZ46536.1 - 2.5e-41 141.8 0.0 4.9e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KEZ46536.1 - 8.1e-40 135.3 0.5 4.2e-39 133.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 KEZ46536.1 - 2e-18 66.1 0.2 7.3e-18 64.3 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KEZ46536.1 - 4.5e-11 43.7 0.0 1.9e-10 41.7 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KEZ46536.1 - 1.4e-09 37.6 0.1 6.6e-09 35.5 0.1 2.2 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KEZ46536.1 - 1.9e-05 24.8 0.2 7.4e-05 22.9 0.2 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KEZ46536.1 - 2.7e-05 23.0 0.5 4.4e-05 22.3 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KEZ46536.1 - 0.00021 20.7 0.1 0.00042 19.8 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KEZ46536.1 - 0.0003 19.7 0.1 0.00049 19.0 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 KEZ46536.1 - 0.00075 18.5 0.0 0.0018 17.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Shikimate_DH PF01488.15 KEZ46536.1 - 0.0037 17.3 0.1 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KEZ46536.1 - 0.011 16.0 0.3 5.6 7.4 0.0 3.2 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KEZ46536.1 - 0.017 15.5 0.6 0.069 13.5 0.0 2.4 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KEZ46536.1 - 0.16 11.9 3.5 0.16 11.9 0.2 2.7 3 1 0 3 3 3 0 NADH(P)-binding NmrA PF05368.8 KEZ46536.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family An_peroxidase PF03098.10 KEZ46537.1 - 1e-84 284.8 0.0 2e-82 277.3 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KEZ46537.1 - 1.2e-13 50.4 0.0 1.9e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 DUF2235 PF09994.4 KEZ46538.1 - 9.6e-74 248.2 4.1 4.9e-72 242.6 1.3 2.9 2 1 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Transferase PF02458.10 KEZ46539.1 - 3e-12 45.7 0.0 2.8e-11 42.5 0.0 2.2 2 1 0 2 2 2 1 Transferase family SBF PF01758.11 KEZ46540.1 - 2.9e-23 82.2 1.7 2.9e-23 82.2 1.2 2.3 2 1 1 3 3 3 1 Sodium Bile acid symporter family DUF3488 PF11992.3 KEZ46541.1 - 2.1 6.9 6.7 2.9 6.4 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) MFS_1 PF07690.11 KEZ46542.1 - 6.3e-25 87.6 21.7 8.1e-25 87.2 15.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATPase_gene1 PF09527.5 KEZ46542.1 - 0.054 13.3 0.2 0.054 13.3 0.1 3.1 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) COesterase PF00135.23 KEZ46543.1 - 1.1e-85 288.4 0.0 1.4e-85 288.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KEZ46543.1 - 2.8e-06 27.0 0.0 0.018 14.6 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Aminotran_1_2 PF00155.16 KEZ46544.1 - 9.7e-12 44.5 0.0 1.9e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KEZ46544.1 - 0.18 10.3 0.0 0.72 8.3 0.0 1.9 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Aldo_ket_red PF00248.16 KEZ46545.1 - 1.2e-38 132.5 0.0 1.6e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HpcH_HpaI PF03328.9 KEZ46546.1 - 4.8e-29 100.8 0.1 1.7e-23 82.6 0.0 2.1 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.13 KEZ46547.1 - 7.9e-18 64.2 0.0 1.2e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KEZ46549.1 - 6e-16 58.0 9.5 6.6e-16 57.9 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ46549.1 - 2.3e-05 23.2 14.3 2.6e-05 23.1 9.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KEZ46550.1 - 0.044 12.5 0.1 0.049 12.3 0.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.11 KEZ46551.1 - 2e-16 59.6 8.6 2.7e-16 59.2 5.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF998 PF06197.8 KEZ46551.1 - 0.79 8.9 13.2 0.28 10.4 3.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF998) Afaf PF15339.1 KEZ46552.1 - 0.096 12.2 0.7 0.11 12.0 0.5 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor Asp PF00026.18 KEZ46552.1 - 0.13 11.5 0.9 0.15 11.2 0.6 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Period_C PF12114.3 KEZ46552.1 - 0.27 10.7 5.3 0.31 10.6 3.6 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CFEM PF05730.6 KEZ46553.1 - 3.6e-16 58.7 14.1 6.2e-16 57.9 9.7 1.4 1 0 0 1 1 1 1 CFEM domain DUF543 PF04418.7 KEZ46553.1 - 0.072 13.0 0.4 0.34 10.8 0.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF543) p450 PF00067.17 KEZ46554.1 - 1.8e-65 221.3 0.0 2.4e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 KEZ46555.1 - 2.1e-93 313.3 19.6 2.4e-93 313.1 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ46555.1 - 2.5e-33 115.2 39.9 5.3e-30 104.3 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1011 PF06237.7 KEZ46555.1 - 0.034 14.0 1.2 0.11 12.4 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) TRI12 PF06609.8 KEZ46555.1 - 0.14 10.2 8.2 0.018 13.2 0.9 2.4 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 KEZ46555.1 - 0.2 11.7 5.2 0.44 10.6 0.9 3.0 2 1 0 3 3 3 0 Phage holin family 2 FAD_binding_4 PF01565.18 KEZ46556.1 - 4.9e-17 61.6 0.6 8.8e-17 60.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ46556.1 - 8.1e-12 44.8 0.0 8.1e-12 44.8 0.0 2.1 3 0 0 3 3 3 1 Berberine and berberine like MFS_1 PF07690.11 KEZ46557.1 - 5.1e-23 81.3 21.3 7e-23 80.8 14.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KEZ46557.1 - 9.7e-06 25.1 3.7 2.3e-05 23.9 2.6 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Aminotran_1_2 PF00155.16 KEZ46558.1 - 2.1e-41 142.0 0.0 2.6e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KEZ46558.1 - 0.0028 16.8 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Ribonuc_L-PSP PF01042.16 KEZ46559.1 - 4.3e-26 91.0 0.0 5.4e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Beta-lactamase PF00144.19 KEZ46560.1 - 1.5e-25 89.9 0.0 2.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.11 KEZ46561.1 - 5.3e-40 137.2 34.6 5.3e-40 137.2 24.0 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_61 PF03443.9 KEZ46562.1 - 1.9e-54 184.8 0.0 2.1e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4337 PF14235.1 KEZ46562.1 - 0.041 13.7 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) p450 PF00067.17 KEZ46564.1 - 2.5e-37 128.5 0.0 4.1e-36 124.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KEZ46565.1 - 4.5e-16 58.4 9.9 5e-16 58.3 6.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2198 PF09964.4 KEZ46565.1 - 5.8 6.7 7.3 1.4 8.7 1.8 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Zn_clus PF00172.13 KEZ46566.1 - 1.1e-17 63.6 28.0 1.5e-09 37.5 6.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ46566.1 - 3.8e-05 22.6 0.0 8.8e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.7 KEZ46566.1 - 4.7 7.4 26.8 5 7.3 6.3 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Cellulase PF00150.13 KEZ46567.1 - 1.7e-49 168.5 10.4 2.8e-49 167.8 7.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NMO PF03060.10 KEZ46567.1 - 3.8e-39 134.7 1.9 3.3e-31 108.6 0.9 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase CBM_1 PF00734.13 KEZ46567.1 - 3.7e-14 52.0 12.2 3.7e-14 52.0 8.5 2.2 3 0 0 3 3 3 1 Fungal cellulose binding domain IMPDH PF00478.20 KEZ46567.1 - 7.4e-10 38.2 0.2 6.5e-05 21.9 0.7 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KEZ46567.1 - 8.2e-07 28.1 3.1 1.3e-06 27.5 2.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KEZ46567.1 - 4.7e-06 25.7 0.3 8e-06 24.9 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Toxin_7 PF05980.7 KEZ46567.1 - 0.082 12.9 3.0 0.15 12.0 2.1 1.5 1 0 0 1 1 1 0 Toxin 7 DHO_dh PF01180.16 KEZ46567.1 - 0.095 11.6 0.8 0.18 10.7 0.5 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FAD_binding_4 PF01565.18 KEZ46569.1 - 1.9e-19 69.5 1.3 1.9e-19 69.5 0.9 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 KEZ46569.1 - 2.2e-08 33.8 0.0 5.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.14 KEZ46571.1 - 1.9e-82 277.1 0.0 2.4e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KEZ46571.1 - 0.001 18.9 0.3 0.0024 17.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ46571.1 - 0.055 12.3 0.2 0.09 11.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glyoxalase PF00903.20 KEZ46572.1 - 2.8e-08 33.7 7.6 4.5e-07 29.8 0.9 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KEZ46572.1 - 4.1e-06 27.3 1.6 0.001 19.6 0.2 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KEZ46572.1 - 0.01 15.8 0.1 1.6 8.7 0.0 3.2 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GFO_IDH_MocA PF01408.17 KEZ46573.1 - 3e-16 60.0 0.0 4.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Alkyl_sulf_dimr PF14863.1 KEZ46574.1 - 3e-54 183.0 0.0 4.8e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 KEZ46574.1 - 1.9e-19 70.0 0.0 3.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 KEZ46574.1 - 7.4e-19 67.9 0.1 1.8e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.2 KEZ46574.1 - 0.0024 17.4 0.0 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SCP2 PF02036.12 KEZ46574.1 - 0.029 14.6 0.1 0.062 13.5 0.1 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family MFS_1 PF07690.11 KEZ46575.1 - 8.4e-39 133.2 49.9 1.5e-36 125.8 23.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KEZ46575.1 - 0.0035 17.0 0.7 0.014 15.2 0.5 2.1 1 0 0 1 1 1 1 MFS_1 like family FokI_C PF02980.11 KEZ46576.1 - 0.086 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain HSP70 PF00012.15 KEZ46577.1 - 0.0018 16.2 0.0 0.075 10.9 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.15 KEZ46577.1 - 0.12 11.6 0.0 0.47 9.7 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Sugar_tr PF00083.19 KEZ46578.1 - 1.5e-86 290.8 22.6 1.8e-86 290.5 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KEZ46578.1 - 8.6e-09 34.5 45.3 2.9e-07 29.5 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 KEZ46578.1 - 0.00065 18.7 0.7 0.0016 17.4 0.5 1.6 1 0 0 1 1 1 1 UAA transporter family NmrA PF05368.8 KEZ46579.1 - 5.1e-16 58.6 0.0 2.9e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KEZ46579.1 - 1.8e-10 41.0 0.1 3.5e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEZ46579.1 - 1.3e-05 24.7 0.6 0.00029 20.3 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KEZ46579.1 - 0.0065 16.3 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase OST-HTH PF12872.2 KEZ46579.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain RAI16-like PF10257.4 KEZ46581.1 - 9.9e-79 264.8 3.9 1.4e-78 264.3 2.7 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Carb_bind PF10645.4 KEZ46582.1 - 4.1e-21 74.5 11.8 4.1e-21 74.5 8.2 1.8 2 0 0 2 2 2 1 Carbohydrate binding Zn_clus PF00172.13 KEZ46585.1 - 6.2e-11 42.0 10.0 1e-10 41.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KEZ46585.1 - 1.4e-10 40.4 4.4 2.2e-10 39.8 3.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF605 PF04652.11 KEZ46586.1 - 0.012 15.0 20.0 0.015 14.7 13.9 1.2 1 0 0 1 1 1 0 Vta1 like PRCC PF10253.4 KEZ46586.1 - 0.02 15.5 2.0 0.02 15.5 1.4 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Suf PF05843.9 KEZ46586.1 - 0.13 12.0 5.1 0.16 11.6 3.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Baculo_PP31 PF05311.6 KEZ46586.1 - 0.21 10.8 5.6 0.33 10.1 3.9 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Ndc1_Nup PF09531.5 KEZ46586.1 - 0.78 8.0 4.8 0.93 7.8 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Amidase PF01425.16 KEZ46587.1 - 2.8e-69 234.1 0.0 8.7e-64 215.9 0.0 2.1 1 1 1 2 2 2 2 Amidase DUF2305 PF10230.4 KEZ46588.1 - 1.7e-59 201.3 0.0 2e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KEZ46588.1 - 1.8e-06 27.9 0.2 2.6e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KEZ46588.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KEZ46588.1 - 0.052 13.2 0.0 0.078 12.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF89 PF01937.14 KEZ46589.1 - 3.5e-133 443.7 0.0 4e-133 443.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Exo_endo_phos PF03372.18 KEZ46590.1 - 1e-19 71.4 0.2 1.5e-19 70.9 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KEZ46590.1 - 1e-13 50.5 5.5 1.1e-07 31.3 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ46590.1 - 5.8e-08 32.3 6.2 3.1e-07 30.0 0.1 2.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KEZ46590.1 - 2.2e-07 29.9 6.7 0.35 11.0 0.0 5.0 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 KEZ46590.1 - 0.0011 18.7 9.1 3.8 8.1 0.0 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 KEZ46590.1 - 1.7 8.9 3.8 8.9 6.7 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Complex1_LYR_2 PF13233.1 KEZ46591.1 - 0.00088 19.7 0.0 0.00095 19.6 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 KEZ46591.1 - 0.014 15.5 0.2 0.026 14.7 0.1 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.10 KEZ46591.1 - 0.032 14.0 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) ProQ PF04352.8 KEZ46592.1 - 0.23 11.0 4.4 2.4 7.8 0.4 2.8 3 0 0 3 3 3 0 ProQ/FINO family ADIP PF11559.3 KEZ46593.1 - 0.0043 16.9 2.1 0.0079 16.1 1.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CLP_protease PF00574.18 KEZ46594.1 - 1.1e-63 214.2 0.0 1.4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Clp protease AAA_12 PF13087.1 KEZ46595.1 - 2.8e-09 36.6 0.0 4.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zn_clus PF00172.13 KEZ46596.1 - 0.00022 21.0 9.7 0.00022 21.0 6.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.7 KEZ46596.1 - 0.04 14.0 0.3 0.04 14.0 0.2 3.6 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KEZ46596.1 - 0.95 9.9 7.8 5.9 7.4 0.4 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Glyco_hydro_6 PF01341.12 KEZ46597.1 - 1.6e-101 339.6 0.3 2e-101 339.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KEZ46597.1 - 1.1e-14 53.7 14.2 2.4e-14 52.6 9.8 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Yeast-kill-tox PF09207.6 KEZ46597.1 - 0.061 13.7 7.0 0.08 13.3 3.1 2.3 2 0 0 2 2 2 0 Yeast killer toxin BAR PF03114.13 KEZ46599.1 - 1.7e-48 165.1 7.1 2.3e-48 164.7 4.9 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KEZ46599.1 - 8.4e-07 28.1 3.3 1.1e-06 27.8 2.3 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Myosin_tail_1 PF01576.14 KEZ46599.1 - 0.00023 19.0 10.6 0.00034 18.5 7.3 1.1 1 0 0 1 1 1 1 Myosin tail F-box-like PF12937.2 KEZ46600.1 - 3.4e-13 49.0 1.8 5.2e-13 48.4 0.6 1.9 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 KEZ46600.1 - 3.8e-12 44.9 11.6 7.1 7.0 0.0 12.0 13 0 0 13 13 13 1 Leucine Rich repeat LRR_4 PF12799.2 KEZ46600.1 - 3.2e-07 29.8 9.8 0.79 9.4 0.0 6.7 5 2 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KEZ46600.1 - 8.7e-06 25.0 18.9 17 5.9 0.0 10.2 10 2 1 11 11 11 1 Leucine Rich Repeat LRR_8 PF13855.1 KEZ46600.1 - 4.4e-05 23.1 15.5 1 9.1 0.0 6.2 3 2 3 7 7 7 4 Leucine rich repeat F-box PF00646.28 KEZ46600.1 - 0.00026 20.5 0.0 0.00087 18.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KEZ46600.1 - 0.077 12.7 0.7 0.31 10.7 0.4 2.2 1 1 0 1 1 1 0 F-box-like domain Peptidase_C37 PF05416.7 KEZ46600.1 - 0.21 9.8 0.0 0.33 9.2 0.0 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Glutaredoxin PF00462.19 KEZ46601.1 - 1.2e-20 73.2 0.0 1.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.15 KEZ46601.1 - 0.0011 18.5 0.1 0.028 13.9 0.0 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 KEZ46601.1 - 0.0047 17.1 0.1 0.0062 16.7 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain adh_short PF00106.20 KEZ46601.1 - 0.0049 16.8 0.0 0.0055 16.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF836 PF05768.9 KEZ46601.1 - 0.0083 16.3 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.1 KEZ46601.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 KEZ46601.1 - 0.025 14.5 0.2 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin GST_N_3 PF13417.1 KEZ46601.1 - 0.038 14.2 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KEZ46601.1 - 0.043 13.3 0.0 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 KEZ46601.1 - 0.056 13.2 0.1 0.15 11.8 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin PF00085.15 KEZ46601.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin ArsC PF03960.10 KEZ46601.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 ArsC family CAP59_mtransfer PF11735.3 KEZ46604.1 - 8.5e-68 228.1 0.0 1.1e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Swi5 PF07061.6 KEZ46605.1 - 2.1e-17 62.6 0.3 2.4e-16 59.2 0.0 2.3 2 0 0 2 2 2 1 Swi5 RRF PF01765.14 KEZ46605.1 - 0.0051 16.2 0.5 0.0091 15.4 0.3 1.4 1 0 0 1 1 1 1 Ribosome recycling factor CCDC-167 PF15188.1 KEZ46605.1 - 0.042 13.8 2.7 3.4 7.6 0.0 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4363 PF14276.1 KEZ46605.1 - 0.13 11.9 2.4 6.7 6.4 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) SKG6 PF08693.5 KEZ46606.1 - 0.0068 15.7 0.9 0.016 14.5 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ribosomal_L13 PF00572.13 KEZ46607.1 - 1.2e-27 96.4 0.0 2.3e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 BAR PF03114.13 KEZ46608.1 - 3.4e-64 216.5 4.8 4.4e-64 216.1 3.3 1.1 1 0 0 1 1 1 1 BAR domain Ammonium_transp PF00909.16 KEZ46609.1 - 2.4e-121 404.9 25.6 2.7e-121 404.8 17.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tweety PF04906.8 KEZ46609.1 - 0.12 10.8 1.7 0.18 10.1 0.6 1.6 2 0 0 2 2 2 0 Tweety WSC PF01822.14 KEZ46610.1 - 2.8e-15 55.9 8.0 2.8e-15 55.9 5.5 1.8 2 0 0 2 2 2 1 WSC domain Herpes_gE PF02480.11 KEZ46610.1 - 0.0014 16.9 0.2 0.0031 15.8 0.0 1.6 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 KEZ46610.1 - 0.0023 17.8 1.1 0.0023 17.8 0.7 3.0 2 1 1 3 3 2 1 Protein of unknown function (DUF1180) DUF912 PF06024.7 KEZ46610.1 - 0.024 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1517 PF07466.6 KEZ46610.1 - 0.038 12.9 3.2 0.065 12.2 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Rifin_STEVOR PF02009.11 KEZ46610.1 - 0.038 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family SKG6 PF08693.5 KEZ46610.1 - 0.045 13.0 3.5 0.095 12.0 2.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RskA PF10099.4 KEZ46610.1 - 0.051 13.3 4.9 0.15 11.8 0.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4448 PF14610.1 KEZ46610.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Mid2 PF04478.7 KEZ46610.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 KEZ46610.1 - 0.14 11.8 0.7 0.3 10.7 0.5 1.5 1 0 0 1 1 1 0 Syndecan domain S1FA PF04689.8 KEZ46610.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA VSP PF03302.8 KEZ46610.1 - 0.61 8.6 17.3 0.88 8.1 10.8 1.8 1 1 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.6 KEZ46610.1 - 1.2 8.7 9.4 0.28 10.7 3.8 1.9 2 1 0 2 2 2 0 Podoplanin Bestrophin PF01062.16 KEZ46611.1 - 2.3e-46 158.0 1.8 2.3e-44 151.5 1.2 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FTSW_RODA_SPOVE PF01098.14 KEZ46614.1 - 0.00081 18.2 2.5 0.001 17.9 1.8 1.1 1 0 0 1 1 1 1 Cell cycle protein DUF2207 PF09972.4 KEZ46614.1 - 0.45 9.0 4.0 0.51 8.8 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 KEZ46614.1 - 1.9 7.8 6.8 2.5 7.4 4.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Glyco_hydro_10 PF00331.15 KEZ46615.1 - 2.9e-99 332.1 0.2 3.6e-99 331.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KEZ46615.1 - 1.7e-15 56.3 11.8 4.3e-15 55.0 8.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Dot_icm_IcmQ PF09475.5 KEZ46615.1 - 0.18 11.0 0.0 0.79 8.9 0.0 1.9 1 1 1 2 2 2 0 Dot/Icm secretion system protein (dot_icm_IcmQ) HC2 PF07382.6 KEZ46616.1 - 7.6e-06 25.9 22.9 0.00015 21.6 5.3 2.0 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 AAA PF00004.24 KEZ46617.1 - 0.00016 21.8 0.0 0.00044 20.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.2 KEZ46617.1 - 0.0004 20.6 0.1 0.0017 18.6 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NACHT PF05729.7 KEZ46617.1 - 0.00079 19.1 2.2 0.0083 15.8 0.2 2.8 2 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 KEZ46617.1 - 0.016 15.2 3.0 0.27 11.1 0.0 3.3 3 1 1 4 4 4 0 AAA ATPase domain Glyco_hydro_72 PF03198.9 KEZ46619.1 - 1.7e-120 401.7 1.1 2.2e-120 401.3 0.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KEZ46619.1 - 4.7e-25 87.8 4.9 1.3e-24 86.5 3.4 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 KEZ46619.1 - 4.3e-05 22.5 0.0 0.00012 21.1 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain OPT PF03169.10 KEZ46620.1 - 2.1e-71 241.2 40.3 5.4e-56 190.3 20.7 2.5 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Cut8_N PF14482.1 KEZ46621.1 - 0.0025 17.7 6.8 0.0054 16.7 4.7 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Radical_SAM PF04055.16 KEZ46622.1 - 8.5e-16 58.5 0.0 2.7e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KEZ46622.1 - 8.1e-12 45.0 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KEZ46622.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 KEZ46623.1 - 7.6e-27 93.6 2.7 5.1e-26 91.0 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KEZ46623.1 - 5.2e-24 84.5 0.2 8.5e-24 83.8 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KEZ46623.1 - 9.3e-09 35.0 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KEZ46623.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 KEZ46623.1 - 0.025 15.0 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UQ_con PF00179.21 KEZ46624.1 - 5.4e-39 132.8 0.0 6.9e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ46624.1 - 4.7e-06 26.3 0.0 6.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_3 PF09288.5 KEZ46624.1 - 5e-05 22.8 0.1 9.1e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UEV PF05743.8 KEZ46624.1 - 0.0028 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 KEZ46624.1 - 0.01 15.7 0.1 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 RWD domain AAA PF00004.24 KEZ46625.1 - 3.4e-41 140.5 0.0 5.9e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KEZ46625.1 - 5.1e-07 29.9 0.1 0.00018 21.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KEZ46625.1 - 1.5e-06 28.2 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KEZ46625.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KEZ46625.1 - 4.2e-05 23.2 0.1 0.00014 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEZ46625.1 - 0.00025 20.1 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEZ46625.1 - 0.00028 20.9 0.6 0.0011 18.9 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_28 PF13521.1 KEZ46625.1 - 0.0011 19.0 0.6 0.0039 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KEZ46625.1 - 0.0022 17.8 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KEZ46625.1 - 0.0039 16.8 0.1 0.34 10.5 0.1 2.5 1 1 1 2 2 2 1 NACHT domain AAA_17 PF13207.1 KEZ46625.1 - 0.0045 17.8 0.5 0.011 16.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 KEZ46625.1 - 0.0063 16.2 0.3 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KEZ46625.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 KEZ46625.1 - 0.0082 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KEZ46625.1 - 0.0085 16.3 0.0 0.021 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KEZ46625.1 - 0.009 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KEZ46625.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KEZ46625.1 - 0.014 14.6 1.4 0.2 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.8 KEZ46625.1 - 0.021 13.5 0.1 0.044 12.4 0.1 1.5 1 1 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 KEZ46625.1 - 0.029 13.4 0.2 0.42 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC NB-ARC PF00931.17 KEZ46625.1 - 0.039 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KEZ46625.1 - 0.043 13.9 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 KEZ46625.1 - 0.052 12.7 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KEZ46625.1 - 0.06 12.9 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KEZ46625.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KEZ46625.1 - 0.24 10.7 5.5 0.23 10.8 0.3 2.7 2 1 1 3 3 3 0 AAA domain Lipase_3 PF01764.20 KEZ46626.1 - 6.4e-19 67.9 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KEZ46626.1 - 0.04 13.2 0.0 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KEZ46626.1 - 0.043 13.5 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ46626.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein CFEM PF05730.6 KEZ46627.1 - 1.5e-06 27.8 10.7 2.2e-06 27.3 7.4 1.3 1 0 0 1 1 1 1 CFEM domain Menin PF05053.8 KEZ46627.1 - 5.2 5.1 6.3 4.7 5.2 4.3 1.1 1 0 0 1 1 1 0 Menin zf-C2H2 PF00096.21 KEZ46628.1 - 0.00083 19.5 2.5 0.0018 18.5 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 KEZ46628.1 - 0.11 12.7 0.5 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 KEZ46628.1 - 0.14 12.5 0.3 0.38 11.2 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Kinocilin PF15033.1 KEZ46629.1 - 0.14 11.7 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 Kinocilin protein Ytp1 PF10355.4 KEZ46630.1 - 3.9e-83 278.7 13.7 3.9e-83 278.7 9.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KEZ46630.1 - 1.3e-22 79.3 3.6 1.3e-22 79.3 2.5 2.9 5 0 0 5 5 5 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 KEZ46630.1 - 0.0003 20.6 4.3 0.0003 20.6 3.0 3.2 4 0 0 4 4 4 1 Eukaryotic cytochrome b561 DUF373 PF04123.8 KEZ46630.1 - 0.051 12.5 4.1 0.96 8.4 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) SUR7 PF06687.7 KEZ46630.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 SUR7/PalI family DUF4225 PF13988.1 KEZ46630.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) DUF3675 PF12428.3 KEZ46630.1 - 0.14 12.4 0.9 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) FAD_binding_4 PF01565.18 KEZ46631.1 - 1.9e-25 88.9 1.3 7.9e-25 86.9 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KEZ46631.1 - 1.8e-13 50.1 0.1 3.5e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.4 KEZ46632.1 - 1.1e-83 281.2 0.0 1.4e-83 280.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FliC PF12445.3 KEZ46632.1 - 0.14 12.3 1.9 0.14 12.3 0.3 1.8 2 0 0 2 2 2 0 Flagellin protein He_PIG PF05345.7 KEZ46632.1 - 0.41 10.6 7.2 0.11 12.4 1.5 2.8 2 1 0 2 2 2 0 Putative Ig domain Acyltransferase PF01553.16 KEZ46633.1 - 1.6e-24 85.8 0.0 2.4e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase GFO_IDH_MocA PF01408.17 KEZ46634.1 - 9e-24 84.2 0.0 1.4e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KEZ46634.1 - 1.5e-12 47.2 0.0 2.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Methyltransf_23 PF13489.1 KEZ46635.1 - 9.9e-18 64.3 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46635.1 - 2.3e-06 27.2 0.0 2.1e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46635.1 - 2.2e-05 24.8 0.0 4.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46635.1 - 2.5e-05 24.7 0.0 7e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46635.1 - 0.00035 21.0 0.0 0.0042 17.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEZ46635.1 - 0.00064 18.9 0.0 0.0029 16.8 0.0 2.0 3 0 0 3 3 3 1 O-methyltransferase Methyltransf_25 PF13649.1 KEZ46635.1 - 0.0013 19.0 0.0 0.0041 17.4 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 KEZ46635.1 - 0.0019 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ46635.1 - 0.046 13.7 0.0 0.054 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 KEZ46635.1 - 0.071 12.1 0.0 0.14 11.1 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 KEZ46635.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 KEZ46635.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Git3 PF11710.3 KEZ46636.1 - 1.7e-16 60.4 2.5 2.8e-16 59.7 1.7 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KEZ46636.1 - 3.4e-06 26.3 3.1 3.4e-06 26.3 2.1 1.6 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 KEZ46636.1 - 0.0029 17.3 0.1 0.0029 17.3 0.1 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term FixP_N PF14715.1 KEZ46636.1 - 4.3 6.8 9.5 5.6 6.4 0.7 2.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP 5_nucleotid_C PF02872.13 KEZ46637.1 - 7.9e-36 123.3 0.1 1.6e-35 122.3 0.1 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KEZ46637.1 - 3.7e-14 52.5 0.1 8.1e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.1 KEZ46637.1 - 4.9e-05 22.4 0.0 0.00079 18.5 0.0 2.5 3 0 0 3 3 3 1 YmdB-like protein PGA_cap PF09587.5 KEZ46637.1 - 0.00089 18.6 0.0 0.002 17.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Ribosomal_S27 PF01599.14 KEZ46637.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S27a NAD_binding_10 PF13460.1 KEZ46639.1 - 1.7e-19 70.5 0.0 4.3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KEZ46639.1 - 7.4e-06 25.5 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KEZ46639.1 - 0.0006 19.3 0.2 0.0021 17.5 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_4 PF07993.7 KEZ46639.1 - 0.00071 18.5 0.0 0.0036 16.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KEZ46639.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 KEZ46639.1 - 0.099 11.8 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family SprT-like PF10263.4 KEZ46639.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 SprT-like family HPP PF04982.8 KEZ46640.1 - 4.5e-35 120.0 8.4 4.5e-35 120.0 5.8 1.6 2 0 0 2 2 2 1 HPP family Mem_trans PF03547.13 KEZ46640.1 - 7.2 4.7 9.8 12 4.0 5.0 1.9 1 1 1 2 2 2 0 Membrane transport protein Cu-oxidase_3 PF07732.10 KEZ46641.1 - 7.1e-44 148.3 4.8 4.3e-41 139.3 0.3 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KEZ46641.1 - 1.1e-40 138.3 9.6 1.4e-36 125.0 0.3 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KEZ46641.1 - 4.9e-37 127.2 0.1 2.3e-31 108.8 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KEZ46641.1 - 0.0039 17.0 0.0 16 5.4 0.0 3.9 4 0 0 4 4 4 2 Cupredoxin-like domain TauD PF02668.11 KEZ46642.1 - 3.2e-27 95.8 0.0 4.1e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KEZ46642.1 - 6.3e-05 22.0 0.0 9.7e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 CsiD Zn_clus PF00172.13 KEZ46643.1 - 0.2 11.5 9.9 0.41 10.5 6.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ufd2P_core PF10408.4 KEZ46645.1 - 0.069 11.3 0.1 0.078 11.2 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core Adap_comp_sub PF00928.16 KEZ46646.1 - 1.7e-84 283.0 0.0 2.3e-84 282.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KEZ46646.1 - 2.7e-05 23.9 0.2 4.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 KEZ46646.1 - 0.02 14.8 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) ABC_tran PF00005.22 KEZ46647.1 - 2.3e-47 160.7 0.0 4.8e-22 78.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KEZ46647.1 - 7.6e-21 73.7 1.6 7.6e-21 73.7 1.1 2.7 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 KEZ46647.1 - 7.6e-20 72.0 0.2 0.00084 19.3 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KEZ46647.1 - 1.2e-10 40.9 0.1 0.35 10.0 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KEZ46647.1 - 1.9e-09 36.9 0.0 0.00083 18.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KEZ46647.1 - 9.6e-08 32.5 5.9 0.03 14.6 0.1 3.6 4 0 0 4 4 3 2 AAA domain DUF258 PF03193.11 KEZ46647.1 - 9.6e-07 28.1 0.0 0.0012 18.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KEZ46647.1 - 4.8e-06 26.7 0.0 0.15 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KEZ46647.1 - 1.1e-05 25.4 0.1 0.058 13.3 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KEZ46647.1 - 2e-05 25.3 0.1 0.25 12.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 KEZ46647.1 - 2.5e-05 24.0 0.2 0.24 11.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 KEZ46647.1 - 4.2e-05 23.8 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KEZ46647.1 - 4.8e-05 23.4 1.5 0.11 12.4 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain Miro PF08477.8 KEZ46647.1 - 8.3e-05 23.0 0.0 0.26 11.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 KEZ46647.1 - 0.00037 20.4 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KEZ46647.1 - 0.0004 20.1 0.1 0.83 9.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.24 KEZ46647.1 - 0.00046 20.3 0.5 1.1 9.4 0.0 3.2 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KEZ46647.1 - 0.00046 20.3 1.3 2.4 8.3 0.0 3.5 3 0 0 3 3 3 2 RNA helicase AAA_15 PF13175.1 KEZ46647.1 - 0.00052 19.1 0.1 0.17 10.8 0.0 2.9 4 0 0 4 4 2 1 AAA ATPase domain AAA_10 PF12846.2 KEZ46647.1 - 0.00057 19.4 0.5 0.77 9.1 0.1 3.0 4 0 0 4 4 2 2 AAA-like domain AAA_33 PF13671.1 KEZ46647.1 - 0.0008 19.3 0.0 0.61 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KEZ46647.1 - 0.00082 19.1 0.1 0.64 9.6 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 KEZ46647.1 - 0.00097 18.5 0.0 0.67 9.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KEZ46647.1 - 0.0018 17.9 0.1 0.045 13.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KEZ46647.1 - 0.003 17.4 0.0 1.9 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF2813 PF11398.3 KEZ46647.1 - 0.0039 16.3 0.2 0.89 8.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NB-ARC PF00931.17 KEZ46647.1 - 0.0045 15.8 0.0 1.1 8.0 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.18 KEZ46647.1 - 0.0078 16.0 0.1 8.2 6.2 0.0 3.4 3 1 1 4 4 4 0 Dynamin family SbcCD_C PF13558.1 KEZ46647.1 - 0.0079 16.0 0.7 0.95 9.4 0.0 3.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit DAP3 PF10236.4 KEZ46647.1 - 0.016 14.1 0.9 3.2 6.5 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 KEZ46647.1 - 0.038 13.4 0.0 0.39 10.1 0.0 2.4 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 KEZ46647.1 - 0.04 12.4 0.0 14 4.1 0.0 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DUF815 PF05673.8 KEZ46647.1 - 0.058 12.3 0.0 3.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KEZ46647.1 - 0.067 12.9 0.1 6.1 6.5 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KEZ46647.1 - 0.085 12.3 0.5 7 6.1 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 KEZ46647.1 - 0.089 11.5 1.2 9.1 4.9 0.0 2.5 3 0 0 3 3 3 0 MCM2/3/5 family ArgK PF03308.11 KEZ46647.1 - 0.13 11.0 0.3 8.8 5.0 0.0 2.5 3 0 0 3 3 3 0 ArgK protein SNF2_N PF00176.18 KEZ46648.1 - 9.6e-72 241.2 2.0 1.8e-71 240.3 1.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KEZ46648.1 - 2.1e-50 170.4 22.2 2.1e-50 170.4 15.4 5.0 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 KEZ46648.1 - 4.6e-16 58.4 0.0 1.1e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Zip PF02535.17 KEZ46649.1 - 2.1e-22 79.5 42.2 3.1e-10 39.5 4.0 3.9 2 1 1 4 4 4 3 ZIP Zinc transporter DNA_primase_lrg PF04104.9 KEZ46650.1 - 2.8e-81 272.6 0.0 5.3e-81 271.7 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Ank PF00023.25 KEZ46651.1 - 4.4e-05 23.0 0.0 0.36 10.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 KEZ46651.1 - 5.2e-05 23.5 0.0 0.002 18.4 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KEZ46651.1 - 0.0096 16.0 0.0 8.8 6.9 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 KEZ46651.1 - 0.055 14.0 0.0 1.8 9.1 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Pkinase PF00069.20 KEZ46652.1 - 1.8e-46 158.3 0.0 7.1e-46 156.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46652.1 - 1.2e-26 93.3 0.0 2.3e-26 92.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46652.1 - 0.1 11.5 0.0 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Clr5 PF14420.1 KEZ46653.1 - 2.3e-19 69.0 0.3 6.6e-19 67.5 0.2 1.8 1 0 0 1 1 1 1 Clr5 domain DUF3433 PF11915.3 KEZ46654.1 - 4.4e-05 23.5 1.9 4.4e-05 23.5 1.3 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3433) GST_N_3 PF13417.1 KEZ46655.1 - 1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KEZ46655.1 - 2.6e-11 43.2 0.1 5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KEZ46655.1 - 2.7e-11 43.3 0.0 5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KEZ46655.1 - 2.7e-11 43.2 0.0 5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KEZ46655.1 - 3.3e-10 39.9 0.0 5.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KEZ46655.1 - 1.7e-08 34.8 0.2 2.8e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MutH PF02976.10 KEZ46655.1 - 0.062 13.1 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH BLOC1_2 PF10046.4 KEZ46656.1 - 0.015 15.4 14.6 0.041 14.0 3.6 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 KEZ46656.1 - 0.24 11.2 4.1 0.27 11.0 0.7 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF641 PF04859.7 KEZ46656.1 - 0.35 10.6 18.3 0.42 10.3 4.4 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) zf-CCHC PF00098.18 KEZ46657.1 - 1.4e-10 40.5 9.9 1.9e-05 24.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KEZ46657.1 - 5.5e-09 35.5 0.2 1e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 KEZ46657.1 - 9.8e-07 28.4 3.6 0.00049 19.7 0.7 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 KEZ46657.1 - 4.5e-06 26.1 0.2 1.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 KEZ46657.1 - 9.1e-05 22.0 6.4 0.018 14.6 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 KEZ46657.1 - 0.0036 16.9 8.9 0.33 10.6 0.6 2.8 1 1 1 2 2 2 2 Zinc knuckle Peptidase_M28 PF04389.12 KEZ46658.1 - 1.3e-29 103.2 0.0 2.1e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KEZ46658.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Med11 PF10280.4 KEZ46659.1 - 1.5e-30 105.6 0.3 1.8e-30 105.3 0.2 1.1 1 0 0 1 1 1 1 Mediator complex protein DUF1539 PF07560.6 KEZ46659.1 - 0.1 12.4 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) WD40 PF00400.27 KEZ46660.1 - 1.8e-50 167.0 28.0 1.4e-10 40.6 1.2 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KEZ46660.1 - 8.5e-39 132.8 0.1 1.3e-38 132.3 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 KEZ46660.1 - 5.2e-05 23.0 0.1 0.0049 16.6 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 KEZ46660.1 - 0.00016 21.3 0.0 0.00037 20.1 0.0 1.7 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 KEZ46660.1 - 0.0017 17.1 0.0 1.8 7.1 0.0 3.7 3 2 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 KEZ46660.1 - 0.034 12.3 0.6 3.8 5.5 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Vps5 PF09325.5 KEZ46661.1 - 1e-87 293.3 7.2 1.6e-87 292.6 5.0 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KEZ46661.1 - 3e-25 88.2 0.5 8.8e-25 86.7 0.0 2.0 2 0 0 2 2 2 1 PX domain BAR PF03114.13 KEZ46661.1 - 0.024 14.1 6.6 0.051 13.0 4.6 1.5 1 0 0 1 1 1 0 BAR domain BAR_3_WASP_bdg PF10456.4 KEZ46661.1 - 0.024 13.8 0.7 0.16 11.2 0.1 2.1 1 1 1 2 2 2 0 WASP-binding domain of Sorting nexin protein PEP-utilisers_N PF05524.8 KEZ46661.1 - 0.031 14.0 0.7 0.031 14.0 0.5 2.8 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Flavin_Reduct PF01613.13 KEZ46662.1 - 6.1e-30 104.1 0.0 1.4e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 Flavin reductase like domain Kinesin PF00225.18 KEZ46663.1 - 2.2e-104 348.7 0.1 4e-104 347.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain WEMBL PF05701.6 KEZ46663.1 - 3.7e-09 35.5 27.6 7e-09 34.6 19.1 1.4 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 KEZ46663.1 - 3.7e-07 28.3 31.4 7.5e-07 27.2 21.7 1.4 1 0 0 1 1 1 1 Myosin tail Reo_sigmaC PF04582.7 KEZ46663.1 - 1e-05 24.9 7.1 0.021 14.0 2.8 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Apolipoprotein PF01442.13 KEZ46663.1 - 0.00084 18.8 16.7 0.00084 18.8 11.6 2.4 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Filament PF00038.16 KEZ46663.1 - 0.016 14.6 33.0 0.51 9.7 22.9 2.7 1 1 0 1 1 1 0 Intermediate filament protein FlaC_arch PF05377.6 KEZ46663.1 - 0.069 13.0 5.6 5.2 7.0 0.0 4.7 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.9 KEZ46663.1 - 0.17 11.2 8.4 1.4 8.2 0.5 3.3 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain IncA PF04156.9 KEZ46663.1 - 0.18 11.4 37.0 0.078 12.5 9.5 3.3 1 1 2 3 3 3 0 IncA protein Prominin PF05478.6 KEZ46663.1 - 0.31 8.5 7.4 0.55 7.6 5.1 1.4 1 0 0 1 1 1 0 Prominin DUF4618 PF15397.1 KEZ46663.1 - 0.79 9.0 20.5 2.8 7.1 9.5 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Baculo_PEP_C PF04513.7 KEZ46663.1 - 0.96 9.2 6.6 1.1 9.1 1.2 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Striatin PF08232.7 KEZ46663.1 - 7.5 6.8 28.4 0.56 10.5 5.5 3.0 1 1 0 2 2 2 0 Striatin family TPR_12 PF13424.1 KEZ46664.1 - 1.9e-07 30.8 3.0 8.7e-05 22.3 0.0 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ46664.1 - 1.7e-06 27.7 5.2 0.096 12.6 0.3 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 KEZ46664.1 - 5.8e-06 26.3 1.3 1.6e-05 24.9 0.9 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 KEZ46664.1 - 7e-05 22.8 2.5 0.00026 21.0 0.0 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 KEZ46664.1 - 0.0058 16.5 0.0 0.057 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Abhydrolase_5 PF12695.2 KEZ46664.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family MobB PF03205.9 KEZ46664.1 - 0.079 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF676 PF05057.9 KEZ46664.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Metallophos PF00149.23 KEZ46665.1 - 7e-17 61.4 0.1 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KEZ46665.1 - 5.3e-08 32.8 0.0 8.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SAP PF02037.22 KEZ46666.1 - 6.2e-15 54.2 0.0 1.4e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KEZ46666.1 - 0.0079 15.7 0.1 0.021 14.3 0.1 1.7 1 1 0 1 1 1 1 HeH/LEM domain Armet PF10208.4 KEZ46666.1 - 0.066 12.8 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding p450 PF00067.17 KEZ46667.1 - 2e-28 99.1 0.0 2.6e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HSP90 PF00183.13 KEZ46669.1 - 2e-255 848.2 35.9 2.4e-255 847.9 24.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 KEZ46669.1 - 2.4e-12 46.6 0.1 2.4e-12 46.6 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KEZ46669.1 - 2.3e-11 43.4 0.1 4.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KEZ46669.1 - 0.02 15.1 0.2 0.02 15.1 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1676) LOH1CR12 PF10158.4 KEZ46669.1 - 0.093 12.5 1.9 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Tumour suppressor protein PVL_ORF50 PF07768.6 KEZ46669.1 - 0.31 11.0 16.2 0.11 12.5 4.7 2.8 2 0 0 2 2 2 0 PVL ORF-50-like family Acyltransferase PF01553.16 KEZ46670.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 1 1 0 1 1 1 0 Acyltransferase ILVD_EDD PF00920.16 KEZ46671.1 - 2e-206 686.4 1.0 2.5e-206 686.1 0.7 1.1 1 0 0 1 1 1 1 Dehydratase family GTP_EFTU_D4 PF14578.1 KEZ46671.1 - 0.02 14.5 3.2 0.3 10.7 0.0 3.5 4 0 0 4 4 4 0 Elongation factor Tu domain 4 5_nucleotid_C PF02872.13 KEZ46671.1 - 0.031 14.2 0.1 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain DOG1 PF14144.1 KEZ46673.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Seed dormancy control Metallophos PF00149.23 KEZ46674.1 - 0.0016 17.8 0.1 0.082 12.2 0.1 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase MBOAT PF03062.14 KEZ46675.1 - 4.5e-35 121.3 20.3 2.2e-34 119.0 14.1 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Saccharop_dh PF03435.13 KEZ46676.1 - 6.1e-132 440.2 0.0 6.9e-132 440.0 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KEZ46676.1 - 9e-07 29.0 0.1 1.5e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KEZ46676.1 - 9.3e-06 25.7 0.3 1.6e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 KEZ46676.1 - 0.00016 21.1 0.6 0.00074 18.9 0.1 2.3 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 KEZ46676.1 - 0.00086 19.5 0.2 0.0024 18.0 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.12 KEZ46676.1 - 0.0012 19.2 0.1 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KEZ46676.1 - 0.0076 16.7 0.6 0.014 15.9 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KEZ46676.1 - 0.016 15.5 0.2 0.037 14.4 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2325 PF10087.4 KEZ46676.1 - 0.072 12.9 0.4 0.2 11.5 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Glyco_transf_8 PF01501.15 KEZ46677.1 - 2e-39 135.4 0.0 3.9e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KEZ46677.1 - 0.0056 16.0 0.0 0.0056 16.0 0.0 1.9 2 0 0 2 2 2 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 KEZ46677.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase zf-RING_2 PF13639.1 KEZ46678.1 - 1.4e-11 44.0 4.9 2.5e-11 43.2 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KEZ46678.1 - 1.9e-11 43.9 1.3 3.5e-11 43.0 0.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KEZ46678.1 - 3.6e-07 29.7 4.4 2.1e-06 27.2 3.3 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KEZ46678.1 - 3.9e-06 26.4 3.0 7.5e-06 25.5 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KEZ46678.1 - 5e-06 26.4 1.8 1.4e-05 24.9 1.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KEZ46678.1 - 5.9e-06 25.9 1.9 1.1e-05 25.0 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KEZ46678.1 - 0.001 18.7 3.1 0.0024 17.5 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KEZ46678.1 - 0.014 15.2 2.9 0.035 13.9 2.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KEZ46678.1 - 0.093 12.6 1.1 0.21 11.5 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Nucleoplasmin PF03066.10 KEZ46678.1 - 0.41 10.1 11.6 0.82 9.1 8.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 KEZ46678.1 - 2.4 8.6 30.2 0.84 10.0 3.6 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ycf1 PF05758.7 KEZ46678.1 - 6.2 4.4 6.4 4.8 4.7 2.7 1.8 2 0 0 2 2 2 0 Ycf1 Ax_dynein_light PF10211.4 KEZ46678.1 - 6.7 6.5 16.2 0.88 9.3 0.3 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain CMD PF02627.15 KEZ46679.1 - 0.0019 18.0 0.0 0.089 12.6 0.0 2.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Allexi_40kDa PF05549.6 KEZ46679.1 - 0.0067 15.7 0.5 0.0099 15.1 0.3 1.4 1 0 0 1 1 1 1 Allexivirus 40kDa protein MscS_porin PF12795.2 KEZ46679.1 - 0.011 15.0 4.4 0.016 14.5 3.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.7 KEZ46679.1 - 0.028 14.6 0.5 1.1 9.5 0.1 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Med15_fungi PF05397.7 KEZ46679.1 - 0.097 12.6 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 15 Uds1 PF15456.1 KEZ46679.1 - 0.11 12.5 1.0 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 Up-regulated During Septation COG2 PF06148.6 KEZ46679.1 - 0.13 12.1 0.4 0.35 10.7 0.3 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 KEZ46679.1 - 0.14 12.0 5.4 0.38 10.5 3.5 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C2H2_4 PF13894.1 KEZ46680.1 - 3.4e-05 23.8 15.5 0.13 12.6 0.0 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ46680.1 - 0.00011 22.2 19.5 1 9.8 0.6 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KEZ46680.1 - 0.014 15.2 1.2 0.15 12.0 0.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 KEZ46680.1 - 0.17 10.4 0.1 2.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 KEZ46680.1 - 1.3 9.3 17.0 0.32 11.3 0.4 4.4 4 1 0 4 4 4 0 Zinc-finger double domain IBR PF01485.16 KEZ46680.1 - 2.9 7.8 10.4 1.2e+03 -0.6 7.2 2.8 1 1 0 1 1 1 0 IBR domain Methyltransf_16 PF10294.4 KEZ46681.1 - 2e-13 50.1 0.0 3.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KEZ46681.1 - 0.0011 19.4 0.0 0.002 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KEZ46681.1 - 0.003 16.7 0.1 0.0041 16.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KEZ46681.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Vps39_2 PF10367.4 KEZ46682.1 - 4.2e-06 26.9 0.0 1.5e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KEZ46682.1 - 0.0068 16.4 0.0 0.096 12.7 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 DUF605 PF04652.11 KEZ46682.1 - 0.35 10.2 6.2 0.69 9.2 4.3 1.5 1 0 0 1 1 1 0 Vta1 like CASP_C PF08172.7 KEZ46683.1 - 2.8e-91 304.9 0.1 2.8e-91 304.9 0.1 3.9 2 1 2 4 4 4 1 CASP C terminal GAS PF13851.1 KEZ46683.1 - 0.074 12.2 58.8 1.2 8.2 3.6 5.4 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 KEZ46683.1 - 2.4 5.3 55.5 0.94 6.7 2.7 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) IncA PF04156.9 KEZ46683.1 - 2.4 7.6 65.4 0.14 11.7 3.1 5.3 3 1 2 5 5 5 0 IncA protein Shugoshin_N PF07558.6 KEZ46683.1 - 3.7 7.3 13.3 0.36 10.5 0.7 3.9 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.6 KEZ46683.1 - 8 6.2 63.5 0.77 9.5 0.1 5.2 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 KEZ46683.1 - 9.2 6.6 46.6 5 7.5 0.0 6.5 4 2 1 6 6 6 0 Protein of unknown function (DUF972) DUF3455 PF11937.3 KEZ46684.1 - 1.1e-40 139.4 0.0 1.5e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) tRNA-synt_1b PF00579.20 KEZ46686.1 - 2.3e-26 92.5 0.0 3.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3716 PF12511.3 KEZ46687.1 - 7.2e-06 25.5 0.2 1.1e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SPRY PF00622.23 KEZ46688.1 - 9.1e-17 61.3 0.0 1.5e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Zn_clus PF00172.13 KEZ46689.1 - 3.5e-08 33.2 10.9 5.5e-08 32.5 7.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KEZ46689.1 - 3.4e-07 29.2 0.2 5.9e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.1 KEZ46690.1 - 6e-29 99.7 9.5 7.2e-13 48.6 0.0 11.0 9 3 3 12 12 12 5 HEAT-like repeat HEAT_2 PF13646.1 KEZ46690.1 - 3.2e-23 81.8 0.6 1.1e-06 28.7 0.0 7.9 3 3 7 10 10 10 8 HEAT repeats HEAT PF02985.17 KEZ46690.1 - 7.6e-23 78.5 16.1 9.9e-06 25.2 0.0 8.9 9 0 0 9 9 8 6 HEAT repeat Vac14_Fab1_bd PF12755.2 KEZ46690.1 - 1.4e-07 31.7 0.3 0.0092 16.3 0.0 5.9 5 3 4 9 9 8 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KEZ46690.1 - 1.4e-07 30.5 0.2 0.0088 14.8 0.1 4.0 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal Arm PF00514.18 KEZ46690.1 - 2.2e-07 30.4 0.7 0.14 12.0 0.0 5.8 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 KEZ46690.1 - 9.1e-07 28.8 0.7 0.57 10.0 0.0 6.0 5 2 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 KEZ46690.1 - 2.1e-05 24.3 0.1 0.00025 20.9 0.1 2.8 1 1 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 KEZ46690.1 - 3.9e-05 22.1 0.0 0.032 12.5 0.0 2.5 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.11 KEZ46690.1 - 0.012 16.0 0.7 22 5.8 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Nipped-B_C PF12830.2 KEZ46690.1 - 0.1 12.2 0.0 15 5.1 0.0 2.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Sua5_yciO_yrdC PF01300.13 KEZ46691.1 - 0.038 13.2 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Telomere recombination N2227 PF07942.7 KEZ46692.1 - 3.8e-96 321.2 0.0 4.9e-96 320.8 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KEZ46692.1 - 9.4e-09 35.1 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46692.1 - 0.0062 16.9 0.0 0.043 14.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46692.1 - 0.11 12.9 0.0 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.20 KEZ46693.1 - 1e-28 100.3 6.0 1.6e-28 99.6 4.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KEZ46693.1 - 2.2e-26 93.0 0.1 3.1e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KEZ46693.1 - 1.3e-15 57.5 3.0 1.9e-15 56.9 2.1 1.2 1 0 0 1 1 1 1 KR domain malic PF00390.14 KEZ46693.1 - 0.067 12.7 0.0 0.83 9.1 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Mem_trans PF03547.13 KEZ46694.1 - 0.12 10.6 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein MIP-T3 PF10243.4 KEZ46694.1 - 0.3 9.5 28.8 0.39 9.1 19.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SRP-alpha_N PF04086.8 KEZ46694.1 - 3.4 6.9 22.0 4.9 6.4 15.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal p450 PF00067.17 KEZ46695.1 - 6.6e-42 143.5 0.1 9.5e-42 143.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FeoB_C PF07664.7 KEZ46695.1 - 0.56 9.6 2.8 0.67 9.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Nitroreductase PF00881.19 KEZ46696.1 - 4.8e-12 46.0 0.0 5.8e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Inh PF02974.9 KEZ46696.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Protease inhibitor Inh Pkinase PF00069.20 KEZ46697.1 - 3.4e-31 108.3 0.0 8.6e-31 107.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46697.1 - 2.4e-07 30.0 0.1 0.031 13.3 0.0 3.2 2 1 1 3 3 3 2 Protein tyrosine kinase HTH_31 PF13560.1 KEZ46697.1 - 0.073 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PS_Dcarbxylase PF02666.10 KEZ46699.1 - 1.5e-80 269.2 0.0 2.7e-80 268.4 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2407 PF10302.4 KEZ46700.1 - 6e-07 29.5 0.1 1.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KEZ46700.1 - 0.0029 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C12 PF01088.16 KEZ46701.1 - 1.7e-70 236.5 0.0 2.2e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF4414 PF14377.1 KEZ46701.1 - 0.11 12.3 0.1 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) MVP_shoulder PF11978.3 KEZ46701.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Shoulder domain PQ-loop PF04193.9 KEZ46702.1 - 1.6e-24 85.2 4.8 1.1e-17 63.2 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF1049 PF06305.6 KEZ46702.1 - 0.21 11.0 7.3 0.59 9.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Dicty_CAR PF05462.6 KEZ46704.1 - 9.7e-14 50.9 6.2 9.7e-14 50.9 4.3 1.6 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KEZ46704.1 - 1.5e-08 34.4 8.5 2.8e-08 33.5 5.9 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KEZ46704.1 - 4.4e-06 26.0 5.1 7.2e-06 25.3 3.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MIP-T3 PF10243.4 KEZ46705.1 - 0.14 10.6 17.3 0.17 10.3 12.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 KEZ46705.1 - 0.14 11.5 18.3 0.15 11.3 12.7 1.1 1 0 0 1 1 1 0 Vta1 like Glycogen_syn PF05693.8 KEZ46705.1 - 0.27 9.4 0.1 0.27 9.4 0.0 2.1 2 0 0 2 2 2 0 Glycogen synthase Macoilin PF09726.4 KEZ46705.1 - 9.6 4.3 11.7 10 4.2 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Fibrillarin PF01269.12 KEZ46706.1 - 2.2e-97 324.5 0.0 2.5e-97 324.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KEZ46706.1 - 4.3e-08 32.9 0.0 5.9e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KEZ46706.1 - 0.0042 16.6 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KEZ46706.1 - 0.0058 16.2 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KEZ46706.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ribosomal_L22 PF00237.14 KEZ46707.1 - 3.9e-35 119.9 0.0 5.6e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Abhydrolase_6 PF12697.2 KEZ46709.1 - 2.3e-19 70.2 0.7 3.8e-19 69.4 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KEZ46709.1 - 1.3e-17 63.3 0.0 3.1e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KEZ46709.1 - 1.8e-15 56.9 0.1 2.4e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ46709.1 - 0.00035 20.2 0.5 0.0054 16.3 0.0 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ46709.1 - 0.00037 19.7 0.2 0.13 11.4 0.1 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.13 KEZ46709.1 - 0.023 13.9 0.2 0.71 9.1 0.1 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KEZ46709.1 - 0.07 12.5 0.1 2.7 7.3 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase CTD_bind PF04818.8 KEZ46710.1 - 2e-21 75.9 0.0 4.5e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.3 KEZ46710.1 - 0.015 14.9 0.2 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 GKAP PF03359.8 KEZ46710.1 - 0.075 12.6 1.3 0.09 12.3 0.3 1.5 1 1 1 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein Clathrin_lg_ch PF01086.12 KEZ46711.1 - 6e-68 229.1 3.6 7.8e-68 228.7 2.5 1.1 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 KEZ46711.1 - 0.014 14.9 0.5 0.03 13.8 0.4 1.6 1 0 0 1 1 1 0 Integrase core domain Synaphin PF05835.7 KEZ46711.1 - 0.018 15.2 2.9 0.033 14.3 2.0 1.5 1 0 0 1 1 1 0 Synaphin protein NfrA_C PF13283.1 KEZ46712.1 - 0.012 15.0 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term EF-hand_1 PF00036.27 KEZ46713.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KEZ46713.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KEZ46713.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KEZ46713.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KEZ46713.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KEZ46713.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KEZ46713.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KEZ46713.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KEZ46713.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KEZ46713.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KEZ46713.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KEZ46713.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 KEZ46713.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KEZ46713.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 KEZ46713.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 KEZ46713.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KEZ46713.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 KEZ46713.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 KEZ46713.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain Adaptin_N PF01602.15 KEZ46714.1 - 8.1e-146 486.4 1.3 9.5e-146 486.1 0.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KEZ46714.1 - 1.3e-16 60.8 0.0 3.2e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KEZ46714.1 - 5.4e-09 36.2 0.1 0.03 14.5 0.0 4.8 3 3 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KEZ46714.1 - 9.1e-05 22.8 0.7 5 7.7 0.0 5.4 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 KEZ46714.1 - 0.00022 21.0 2.3 8.1 6.8 0.0 5.6 5 1 1 6 6 6 1 HEAT repeat Cnd1 PF12717.2 KEZ46714.1 - 0.005 16.7 4.8 0.019 14.8 0.3 3.3 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 KEZ46714.1 - 0.012 15.2 0.6 0.1 12.2 0.0 2.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 KEZ46714.1 - 0.014 15.1 0.1 61 3.6 0.1 5.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat G-patch_2 PF12656.2 KEZ46714.1 - 0.097 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site Sec39 PF08314.6 KEZ46715.1 - 7.7e-164 546.4 0.0 4e-146 487.8 0.0 2.0 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Ndufs5 PF10200.4 KEZ46716.1 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KEZ46716.1 - 0.024 14.7 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.12 KEZ46716.1 - 0.052 13.5 0.1 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb RRM_1 PF00076.17 KEZ46717.1 - 2.6e-20 71.8 0.0 3.9e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ46717.1 - 3.6e-15 55.6 0.0 5.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ46717.1 - 4.4e-12 45.6 0.0 6.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MarR_2 PF12802.2 KEZ46718.1 - 0.042 13.5 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 MarR family SMC_N PF02463.14 KEZ46719.1 - 4.9e-60 202.4 0.0 2.4e-59 200.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KEZ46719.1 - 3.7e-26 91.4 0.3 3.7e-25 88.2 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KEZ46719.1 - 3.5e-11 43.7 14.9 3.5e-11 43.7 10.3 6.0 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KEZ46719.1 - 1.2e-10 41.9 11.0 1.9e-05 24.8 0.9 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KEZ46719.1 - 2.2e-08 33.5 0.0 4.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 KEZ46719.1 - 0.008 16.0 1.3 0.023 14.5 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 KEZ46719.1 - 0.016 14.4 22.2 0.35 9.9 0.6 4.8 4 1 2 6 6 6 0 Reovirus sigma C capsid protein DUF948 PF06103.6 KEZ46719.1 - 6.7 6.6 28.6 0.28 11.0 0.4 5.5 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) TFIIE_alpha PF02002.12 KEZ46720.1 - 1.2e-14 53.7 0.4 2.3e-14 52.7 0.3 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit Nudix_N_2 PF14803.1 KEZ46720.1 - 0.039 13.6 1.3 0.34 10.6 1.4 2.1 1 1 1 2 2 2 0 Nudix N-terminal GFA PF04828.9 KEZ46720.1 - 0.14 12.0 1.8 2.7 8.0 0.1 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 KEZ46720.1 - 0.28 11.0 1.3 1.3 8.9 0.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Nop14 PF04147.7 KEZ46720.1 - 0.38 8.6 8.2 0.62 7.9 5.7 1.3 1 0 0 1 1 1 0 Nop14-like family zinc_ribbon_2 PF13240.1 KEZ46720.1 - 0.45 10.0 3.2 3.4 7.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain FAM176 PF14851.1 KEZ46720.1 - 4 7.0 13.1 4.7 6.8 0.0 2.9 3 0 0 3 3 3 0 FAM176 family DUF3944 PF13099.1 KEZ46720.1 - 7.4 6.1 7.7 1.8 8.1 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3944) DNA_pol_B_thumb PF14791.1 KEZ46721.1 - 1.2e-19 69.6 0.0 2.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KEZ46721.1 - 1.2e-17 63.9 0.0 2.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KEZ46721.1 - 3.8e-11 43.0 0.0 6.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Sec7 PF01369.15 KEZ46722.1 - 2.6e-38 131.5 0.0 4.2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KEZ46722.1 - 5.8e-05 23.2 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KEZ46722.1 - 8.5e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF2414 PF10309.4 KEZ46723.1 - 3.5e-21 74.6 0.1 8.5e-21 73.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KEZ46723.1 - 0.14 12.1 0.1 0.78 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA binding domain DUF4592 PF15262.1 KEZ46723.1 - 1.5 9.3 6.3 0.24 11.9 0.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) Glyco_transf_41 PF13844.1 KEZ46724.1 - 1.8e-67 227.3 0.0 2.2e-36 124.8 0.0 3.1 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KEZ46724.1 - 1.3e-17 63.1 2.8 1.5e-05 24.4 0.1 4.6 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.23 KEZ46724.1 - 7e-14 50.7 0.8 0.0042 16.6 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46724.1 - 2.4e-10 39.5 0.6 0.71 9.9 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46724.1 - 8.2e-10 37.7 0.1 0.0056 16.3 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ46724.1 - 2.6e-09 36.5 0.0 0.028 14.5 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46724.1 - 2.8e-09 37.3 2.4 0.2 12.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ46724.1 - 2.6e-08 33.6 1.5 8.6e-06 25.6 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ46724.1 - 8e-08 32.2 6.3 0.038 14.6 0.0 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ46724.1 - 5.2e-06 26.2 8.2 0.27 11.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46724.1 - 0.00049 19.7 0.6 0.52 10.2 0.0 4.0 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46724.1 - 0.0028 17.9 0.2 5.7 7.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ46724.1 - 0.052 13.3 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.10 KEZ46725.1 - 3.8e-79 265.4 0.0 5.4e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KEZ46725.1 - 1.9e-34 117.1 0.7 5.6e-34 115.6 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KEZ46725.1 - 4.7e-31 107.1 0.2 1.1e-30 106.0 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KEZ46725.1 - 7.8e-17 60.5 6.6 1.5e-16 59.6 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Ribosomal_L11_N PF03946.9 KEZ46725.1 - 7.3e-16 57.3 0.0 1.8e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Gelsolin PF00626.17 KEZ46725.1 - 3e-13 49.2 0.0 7.8e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11 PF00298.14 KEZ46725.1 - 2.6e-10 40.2 0.2 5.5e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cpn60_TCP1 PF00118.19 KEZ46726.1 - 4.5e-124 414.7 6.8 5.3e-124 414.4 4.7 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3359 PF11839.3 KEZ46726.1 - 3.5 8.0 9.7 0.66 10.3 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) HET PF06985.6 KEZ46727.1 - 6.9e-30 104.0 0.2 1.1e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 KEZ46729.1 - 3.8e-35 121.2 64.4 1.2e-32 113.0 38.0 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ46729.1 - 4.8e-07 28.7 16.4 4.8e-07 28.7 11.4 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter Cation_efflux PF01545.16 KEZ46729.1 - 0.73 8.8 22.7 0.11 11.5 9.5 2.5 2 0 0 2 2 2 0 Cation efflux family AA_permease_2 PF13520.1 KEZ46730.1 - 1.4e-36 125.9 49.9 1.7e-36 125.6 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ46730.1 - 2.4e-11 42.6 43.5 3.3e-11 42.2 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.3 KEZ46731.1 - 2.3e-15 56.1 0.0 3.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46731.1 - 1.3e-09 37.8 8.3 2.4e-09 36.9 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 KEZ46732.1 - 3.4e-25 89.3 0.0 5.6e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.8 KEZ46733.1 - 1.6e-08 34.8 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NAD_binding_1 PF00175.16 KEZ46734.1 - 8.9e-24 84.1 0.0 2.1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KEZ46734.1 - 7.3e-18 64.5 0.0 1.9e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KEZ46734.1 - 8.3e-06 25.7 0.1 0.0006 19.7 0.0 2.4 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KEZ46734.1 - 0.0058 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Glyco_hydro_11 PF00457.12 KEZ46735.1 - 7.2e-70 234.0 17.3 8.5e-70 233.8 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Peptidase_C14 PF00656.17 KEZ46737.1 - 6.7e-67 225.7 0.0 8.4e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KEZ46737.1 - 0.08 12.7 0.1 0.35 10.7 0.0 2.0 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain WW PF00397.21 KEZ46738.1 - 7.7e-10 38.4 3.3 1.8e-09 37.2 2.3 1.7 1 0 0 1 1 1 1 WW domain TPR_2 PF07719.12 KEZ46738.1 - 0.00075 19.2 4.3 0.14 12.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4398 PF14346.1 KEZ46738.1 - 0.0097 15.9 6.4 0.019 15.0 4.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) DUF2853 PF11015.3 KEZ46738.1 - 0.1 13.0 4.8 2.1 8.8 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2853) DUF2076 PF09849.4 KEZ46738.1 - 0.33 10.9 26.6 87 3.0 18.5 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TPR_1 PF00515.23 KEZ46738.1 - 0.95 9.1 7.2 0.13 11.8 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Gly-zipper_OmpA PF13436.1 KEZ46738.1 - 4.9 6.8 7.9 0.86 9.2 2.5 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Na_trans_assoc PF06512.8 KEZ46738.1 - 6.6 6.6 7.9 2.4 8.0 3.3 1.7 2 0 0 2 2 2 0 Sodium ion transport-associated TPR_12 PF13424.1 KEZ46738.1 - 6.7 6.7 7.7 3.7e+02 1.1 5.3 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat Ish1 PF10281.4 KEZ46739.1 - 1.2e-60 201.0 29.2 2.9e-10 40.0 0.0 9.2 8 1 0 8 8 8 8 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KEZ46739.1 - 2.6e-11 42.8 0.0 1.2 8.7 0.0 6.7 7 0 0 7 7 7 4 HeH/LEM domain SAP PF02037.22 KEZ46739.1 - 3.7e-11 42.2 0.0 1.3 8.5 0.0 7.4 7 0 0 7 7 7 3 SAP domain Slx4 PF09494.5 KEZ46739.1 - 3.5e-07 29.8 7.4 2.2 8.0 0.0 6.6 7 0 0 7 7 7 3 Slx4 endonuclease APC2 PF08672.6 KEZ46739.1 - 2.6e-05 24.3 4.6 14 5.9 0.0 7.0 8 0 0 8 8 8 1 Anaphase promoting complex (APC) subunit 2 DUF445 PF04286.7 KEZ46739.1 - 0.0031 17.1 3.2 0.0059 16.1 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF445) CPSase_sm_chain PF00988.17 KEZ46739.1 - 0.065 12.7 0.0 7.8 6.0 0.0 3.6 4 0 0 4 4 4 0 Carbamoyl-phosphate synthase small chain, CPSase domain DUF3231 PF11553.3 KEZ46739.1 - 0.12 11.8 0.1 39 3.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3231) SAM_2 PF07647.12 KEZ46739.1 - 1.9 8.4 6.3 6 6.8 0.1 4.6 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) DUF883 PF05957.8 KEZ46739.1 - 2.6 8.4 13.7 20 5.6 0.1 5.1 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF883) Tic20 PF09685.5 KEZ46740.1 - 1.5e-06 28.1 1.3 2e-06 27.7 0.9 1.1 1 0 0 1 1 1 1 Tic20-like protein Reticulon PF02453.12 KEZ46740.1 - 0.013 15.1 1.0 0.019 14.5 0.7 1.2 1 0 0 1 1 1 0 Reticulon Vac_ImportDeg PF09783.4 KEZ46741.1 - 7.5e-64 214.4 0.8 1.1e-63 213.8 0.5 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0020 PF01170.13 KEZ46742.1 - 1.1e-10 41.4 0.0 1.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KEZ46742.1 - 1.2e-06 28.5 0.0 2.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ribonuc_P_40 PF08584.6 KEZ46743.1 - 6.1e-28 97.6 0.2 3.5e-18 65.6 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit RNA_lig_T4_1 PF09511.5 KEZ46744.1 - 1.1e-80 270.2 0.0 2.2e-80 269.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KEZ46744.1 - 7.3e-77 258.0 0.1 1e-76 257.5 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KEZ46744.1 - 4e-51 173.2 0.0 9.1e-51 172.0 0.0 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 KEZ46744.1 - 0.00034 21.4 0.6 0.0048 17.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KEZ46744.1 - 0.0028 17.5 0.6 0.014 15.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KEZ46744.1 - 0.031 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KEZ46744.1 - 0.036 14.3 0.0 0.18 12.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEZ46744.1 - 0.11 12.5 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KEZ46745.1 - 3.5e-40 137.2 0.0 8.7e-40 135.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KEZ46745.1 - 0.00022 20.9 0.6 0.00089 18.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KEZ46745.1 - 0.00025 20.1 0.0 0.00055 19.0 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KEZ46745.1 - 0.00028 20.9 0.6 0.016 15.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 KEZ46745.1 - 0.0014 18.5 0.0 0.0096 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KEZ46745.1 - 0.0036 16.5 0.4 0.038 13.2 0.1 2.4 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 KEZ46745.1 - 0.0068 16.5 4.4 0.018 15.1 0.0 3.0 3 1 1 4 4 3 1 AAA domain Mg_chelatase PF01078.16 KEZ46745.1 - 0.0097 15.0 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KEZ46745.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ46745.1 - 0.015 15.0 0.5 0.035 13.8 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KEZ46745.1 - 0.022 14.1 0.1 0.048 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 KEZ46745.1 - 0.026 13.4 0.0 0.055 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 KEZ46745.1 - 0.039 13.3 1.2 0.34 10.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KEZ46745.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KEZ46745.1 - 0.073 12.9 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KEZ46745.1 - 0.097 13.4 0.1 0.097 13.4 0.1 2.8 2 2 0 2 2 2 0 AAA domain Herpes_UL25 PF01499.11 KEZ46745.1 - 0.14 10.4 0.3 0.2 9.9 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family AAA_11 PF13086.1 KEZ46745.1 - 0.17 11.4 0.9 0.64 9.5 0.0 2.3 2 2 0 2 2 2 0 AAA domain Adaptin_N PF01602.15 KEZ46746.1 - 1.4e-95 320.6 3.8 2.4e-95 319.8 2.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KEZ46746.1 - 2.2e-62 208.5 0.1 6.1e-62 207.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KEZ46746.1 - 1.6e-61 206.1 0.6 3.1e-61 205.1 0.4 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KEZ46746.1 - 1.9e-11 44.0 8.7 3.5e-07 30.4 0.0 4.3 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.2 KEZ46746.1 - 5.5e-06 26.3 3.5 0.0018 18.1 0.0 4.0 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KEZ46746.1 - 0.0003 20.6 0.7 0.6 10.3 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat DUF2603 PF10788.4 KEZ46746.1 - 0.014 15.1 1.7 0.047 13.4 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) HEAT_EZ PF13513.1 KEZ46746.1 - 0.023 15.1 5.2 2.9 8.4 0.0 4.4 3 1 1 4 4 4 0 HEAT-like repeat RE_Alw26IDE PF09665.5 KEZ46746.1 - 0.35 9.5 2.1 2 7.0 0.1 2.7 2 1 1 3 3 3 0 Type II restriction endonuclease (RE_Alw26IDE) Mago_nashi PF02792.9 KEZ46747.1 - 1.5e-75 251.7 0.3 1.7e-75 251.4 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein ubiquitin PF00240.18 KEZ46748.1 - 3.6e-05 23.0 0.0 6.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KEZ46748.1 - 7.2e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KEZ46748.1 - 0.045 13.9 0.2 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF4141 PF13605.1 KEZ46748.1 - 0.81 8.9 2.6 2.9 7.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4141) EF-1_beta_acid PF10587.4 KEZ46748.1 - 9.5 6.4 8.4 1.2 9.3 2.8 1.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Nop52 PF05997.7 KEZ46749.1 - 7.3e-46 156.3 0.0 8.6e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF3808 PF10300.4 KEZ46750.1 - 5.4e-124 414.3 0.0 7.5e-124 413.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DSS1_SEM1 PF05160.8 KEZ46751.1 - 8.6e-22 76.6 14.8 1.1e-21 76.3 10.2 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.3 KEZ46751.1 - 0.17 11.4 2.9 0.2 11.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) ETAA1 PF15350.1 KEZ46751.1 - 0.4 8.6 3.6 0.38 8.7 2.5 1.0 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue PGK PF00162.14 KEZ46752.1 - 1.1e-151 504.7 0.3 1.3e-151 504.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.17 KEZ46752.1 - 0.0041 16.7 0.3 0.062 12.9 0.0 2.6 2 0 0 2 2 2 1 PA domain Brix PF04427.13 KEZ46753.1 - 1.4e-55 187.9 0.0 1.8e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF4455 PF14643.1 KEZ46753.1 - 0.0017 17.0 7.5 0.0026 16.4 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) RNase_H2-Ydr279 PF09468.5 KEZ46753.1 - 5.8 6.0 8.0 7.9 5.5 5.6 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DEAD PF00270.24 KEZ46754.1 - 1.8e-47 160.9 0.0 3e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KEZ46754.1 - 1.1e-27 95.6 0.8 1.8e-25 88.5 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KEZ46754.1 - 0.0024 17.7 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Kinesin PF00225.18 KEZ46755.1 - 5.6e-56 189.6 0.0 1.1e-55 188.7 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 KEZ46755.1 - 0.05 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 KEZ46755.1 - 0.68 9.8 8.9 1.2 9.0 2.3 3.2 3 0 0 3 3 3 0 Basic region leucine zipper SET PF00856.23 KEZ46757.1 - 6.6e-12 46.0 0.1 4.3e-11 43.3 0.0 2.5 2 1 0 2 2 2 1 SET domain Pol_alpha_B_N PF08418.5 KEZ46758.1 - 0.0021 17.6 1.3 0.0051 16.3 0.9 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Ras PF00071.17 KEZ46759.1 - 6.4e-50 168.6 0.0 7.8e-50 168.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KEZ46759.1 - 2.4e-15 57.0 0.0 3.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KEZ46759.1 - 2.3e-05 23.7 0.0 4e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KEZ46759.1 - 0.0095 15.0 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KEZ46759.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KEZ46759.1 - 0.097 12.1 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KEZ46759.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NST1 PF13945.1 KEZ46760.1 - 1.3e-43 149.2 15.9 1.3e-43 149.2 11.0 6.0 3 2 2 6 6 6 1 Salt tolerance down-regulator TFIIA PF03153.8 KEZ46760.1 - 0.0016 18.4 13.4 0.0016 18.4 9.3 5.7 3 1 1 5 5 5 1 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.13 KEZ46760.1 - 0.006 14.9 0.0 0.17 10.1 0.0 2.4 1 1 0 1 1 1 1 Membrane transport protein PUA PF01472.15 KEZ46761.1 - 7.5e-14 51.2 0.4 6.1e-13 48.3 0.3 2.1 1 1 0 1 1 1 1 PUA domain Inhibitor_I78 PF11720.3 KEZ46761.1 - 1.3e-10 40.8 0.0 2.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KEZ46761.1 - 0.0049 16.9 0.1 0.012 15.7 0.1 1.7 1 0 0 1 1 1 1 Potato inhibitor I family ChAPs PF09295.5 KEZ46763.1 - 1.3e-154 514.7 0.0 1.7e-154 514.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 KEZ46763.1 - 5.2e-06 26.6 4.1 0.42 11.3 0.0 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46763.1 - 3.3e-05 24.1 0.2 0.92 9.8 0.0 3.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46763.1 - 0.00018 21.1 0.3 0.48 10.4 0.1 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ46763.1 - 0.00043 19.8 0.6 1.3 8.7 0.0 3.2 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.1 KEZ46763.1 - 0.0028 17.3 0.1 3.1 7.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46763.1 - 0.0081 15.8 0.3 8.3 6.4 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46763.1 - 0.018 15.6 3.4 11 6.8 0.2 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KEZ46763.1 - 0.018 15.1 0.2 7.7 6.7 0.1 3.0 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KEZ46763.1 - 0.022 14.6 2.0 0.27 11.1 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46763.1 - 0.033 13.8 0.1 8 6.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FTCD PF02971.9 KEZ46763.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase domain TPR_12 PF13424.1 KEZ46763.1 - 0.22 11.5 3.8 5.3 7.0 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat AdoHcyase PF05221.12 KEZ46764.1 - 1.6e-137 456.7 0.2 1.9e-137 456.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KEZ46764.1 - 4.3e-85 283.5 2.7 6.6e-85 282.9 1.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KEZ46764.1 - 5.3e-08 32.2 0.2 1.1e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KEZ46764.1 - 0.004 16.5 0.3 0.0071 15.7 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 KEZ46764.1 - 0.011 15.3 0.1 0.021 14.3 0.1 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 KEZ46764.1 - 0.027 14.4 0.1 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain TMEM107 PF14995.1 KEZ46764.1 - 0.032 14.3 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 3HCDH_N PF02737.13 KEZ46764.1 - 0.039 13.6 0.7 0.074 12.7 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain JAB PF01398.16 KEZ46765.1 - 9.7e-08 31.7 0.1 6.3e-07 29.1 0.1 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PA_decarbox PF05870.6 KEZ46765.1 - 0.086 12.3 0.5 0.35 10.3 0.2 2.1 2 1 1 3 3 3 0 Phenolic acid decarboxylase (PAD) ABM PF03992.11 KEZ46766.1 - 0.1 12.6 0.0 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase 2-Hacid_dh_C PF02826.14 KEZ46767.1 - 5.6e-54 181.9 0.0 8e-54 181.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KEZ46767.1 - 5.3e-20 71.2 0.0 1.4e-19 69.9 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KEZ46767.1 - 1.2e-05 25.2 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 KEZ46768.1 - 4.8e-08 32.7 11.1 7.2e-08 32.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cid2 PF09774.4 KEZ46769.1 - 9.8e-48 162.0 0.0 1.1e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 KEZ46770.1 - 4.5e-201 669.1 26.1 6.3e-200 665.3 11.2 2.9 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 KEZ46770.1 - 6.1e-27 93.7 27.6 7.1e-06 26.2 0.1 8.6 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ46770.1 - 2.2e-22 78.4 24.7 9.2e-06 25.2 0.1 8.4 6 2 4 10 10 10 8 TPR repeat TPR_16 PF13432.1 KEZ46770.1 - 1.5e-21 76.5 31.7 0.00018 22.0 3.1 8.7 8 2 2 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46770.1 - 1.2e-20 71.7 25.4 0.00011 21.8 0.0 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ46770.1 - 2.9e-18 64.7 30.4 0.0044 17.5 0.0 11.8 8 4 4 12 12 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46770.1 - 5.9e-14 50.9 19.8 1.3e-06 27.7 0.1 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ46770.1 - 1.1e-11 44.4 21.0 0.22 11.5 0.1 7.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ46770.1 - 8.9e-11 41.4 10.7 0.00066 19.4 0.1 5.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ46770.1 - 2.3e-09 36.7 13.2 0.26 11.5 0.0 9.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46770.1 - 3.2e-09 35.9 9.4 0.00043 19.8 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 KEZ46770.1 - 1e-06 28.0 15.7 0.00086 18.4 0.5 4.3 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ46770.1 - 6.2e-06 26.1 13.5 0.024 15.0 1.9 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46770.1 - 0.0014 18.2 18.6 0.31 10.9 0.0 7.6 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_3 PF07720.7 KEZ46770.1 - 0.0035 17.1 0.3 0.043 13.6 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ46770.1 - 0.01 16.2 25.9 0.63 10.6 0.1 9.9 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_10 PF13374.1 KEZ46770.1 - 0.12 12.3 14.3 4.7 7.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KEZ46770.1 - 4.9 7.1 14.2 0.66 9.9 0.1 5.7 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat DAGK_cat PF00781.19 KEZ46771.1 - 5.9e-26 90.4 1.2 1.5e-25 89.1 0.0 2.2 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain NPCBM_assoc PF10633.4 KEZ46771.1 - 0.062 13.3 0.1 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF676 PF05057.9 KEZ46772.1 - 2.9e-08 33.2 0.0 4.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KEZ46772.1 - 7.3e-06 25.7 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ46772.1 - 1.9e-05 24.6 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ46772.1 - 0.00024 20.7 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.17 KEZ46772.1 - 0.00074 19.2 0.0 0.00093 18.9 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF829 PF05705.9 KEZ46772.1 - 0.0044 16.7 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_9 PF10081.4 KEZ46772.1 - 0.015 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Lipase_3 PF01764.20 KEZ46772.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 KEZ46772.1 - 0.032 13.3 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_8 PF06259.7 KEZ46772.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Disulph_isomer PF06491.6 KEZ46772.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase DUF676 PF05057.9 KEZ46773.1 - 1.2e-06 28.0 0.0 2.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KEZ46773.1 - 0.0053 16.6 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KEZ46773.1 - 0.0065 16.0 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KEZ46773.1 - 0.024 14.3 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1237 PF06824.6 KEZ46773.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) Abhydrolase_6 PF12697.2 KEZ46774.1 - 0.01 15.7 0.2 0.031 14.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_16 PF13191.1 KEZ46774.1 - 0.018 15.0 1.1 0.061 13.3 0.8 1.8 1 1 1 2 2 2 0 AAA ATPase domain Abhydrolase_5 PF12695.2 KEZ46774.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KEZ46774.1 - 0.23 10.7 0.0 0.48 9.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF605 PF04652.11 KEZ46774.1 - 1.7 7.9 15.4 3 7.1 10.7 1.3 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_18 PF00704.23 KEZ46775.1 - 2.3e-37 129.2 1.9 2.3e-37 129.2 1.3 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.15 KEZ46775.1 - 6e-16 58.0 5.6 2.3e-07 30.5 0.0 3.4 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.14 KEZ46775.1 - 3.6e-05 23.6 1.8 3.6e-05 23.6 1.3 3.7 3 0 0 3 3 3 1 Chitin recognition protein DUF1349 PF07081.6 KEZ46776.1 - 1e-14 54.2 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Abhydrolase_6 PF12697.2 KEZ46777.1 - 1.1e-20 74.4 0.5 7.8e-20 71.7 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ46777.1 - 1.4e-09 37.8 0.0 0.0015 18.3 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KEZ46777.1 - 5.1e-07 29.4 0.0 1.5e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KEZ46777.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S24 PF00717.18 KEZ46779.1 - 8.4e-08 31.7 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Oxidored_q2 PF00420.19 KEZ46779.1 - 0.05 13.1 0.4 0.05 13.1 0.3 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Mpv17_PMP22 PF04117.7 KEZ46780.1 - 1.3e-21 75.9 0.3 1.3e-21 75.9 0.2 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family tRNA-synt_1b PF00579.20 KEZ46781.1 - 4.8e-56 190.0 0.0 6e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ATP_bind_1 PF03029.12 KEZ46782.1 - 1.3e-74 250.7 0.0 2.7e-74 249.7 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KEZ46782.1 - 9.4e-06 24.5 0.2 0.01 14.6 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KEZ46782.1 - 7.7e-05 22.8 0.0 0.00032 20.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KEZ46782.1 - 0.0001 21.4 0.1 0.00035 19.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 KEZ46782.1 - 0.00011 21.8 0.3 0.00038 19.9 0.2 1.9 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 KEZ46782.1 - 0.00035 20.5 0.0 0.00096 19.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KEZ46782.1 - 0.00045 19.7 0.2 0.027 13.9 0.2 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KEZ46782.1 - 0.00073 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KEZ46782.1 - 0.00078 20.2 0.3 0.0046 17.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 KEZ46782.1 - 0.0009 19.7 0.0 0.51 10.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KEZ46782.1 - 0.00097 19.1 0.0 0.0033 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KEZ46782.1 - 0.0014 18.3 0.1 0.0038 16.9 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 KEZ46782.1 - 0.002 17.5 0.0 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 KEZ46782.1 - 0.0023 17.5 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KEZ46782.1 - 0.0024 16.7 0.0 0.0052 15.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KEZ46782.1 - 0.0027 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 KEZ46782.1 - 0.0027 17.4 0.1 0.18 11.4 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase DUF4455 PF14643.1 KEZ46782.1 - 0.0032 16.1 0.3 0.0047 15.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) FeoB_N PF02421.13 KEZ46782.1 - 0.0054 16.0 0.0 0.089 12.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B UPF0079 PF02367.12 KEZ46782.1 - 0.0058 16.2 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Arf PF00025.16 KEZ46782.1 - 0.0071 15.5 0.1 1.8 7.8 0.0 2.7 3 1 0 3 3 2 1 ADP-ribosylation factor family PRK PF00485.13 KEZ46782.1 - 0.0073 15.8 0.0 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 KEZ46782.1 - 0.008 15.6 0.0 0.22 10.9 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KEZ46782.1 - 0.01 16.1 0.0 0.059 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KEZ46782.1 - 0.018 14.0 0.0 0.035 13.0 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain G-alpha PF00503.15 KEZ46782.1 - 0.04 12.5 1.7 0.77 8.3 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 KEZ46782.1 - 0.042 13.1 0.0 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein U1snRNP70_N PF12220.3 KEZ46782.1 - 0.049 13.9 1.1 0.1 12.9 0.7 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal APS_kinase PF01583.15 KEZ46782.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 KEZ46782.1 - 0.077 12.3 0.6 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase DUF258 PF03193.11 KEZ46782.1 - 0.097 11.8 0.0 0.7 9.0 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 KEZ46782.1 - 0.12 11.6 0.2 6.8 5.8 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DNA_RNApol_7kD PF03604.8 KEZ46783.1 - 4e-10 38.9 5.2 5.8e-10 38.4 3.6 1.3 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-C4_ClpX PF06689.8 KEZ46783.1 - 0.13 11.7 2.7 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 ClpX C4-type zinc finger TF_Zn_Ribbon PF08271.7 KEZ46783.1 - 0.44 9.9 7.2 0.49 9.7 0.2 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding zf-BED PF02892.10 KEZ46783.1 - 2 8.2 4.5 1.5 8.6 2.1 1.6 1 1 1 2 2 2 0 BED zinc finger Aldo_ket_red PF00248.16 KEZ46784.1 - 2.7e-51 174.0 0.0 3.2e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.13 KEZ46784.1 - 0.17 10.3 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase HLH PF00010.21 KEZ46785.1 - 4.2e-10 39.1 0.0 4.2e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain UQ_con PF00179.21 KEZ46787.1 - 3.2e-38 130.3 0.0 5.1e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KEZ46787.1 - 0.0042 16.8 0.0 0.0096 15.6 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic E2 family B TPR_11 PF13414.1 KEZ46788.1 - 0.0014 18.2 4.0 3.7 7.2 0.1 5.0 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 KEZ46788.1 - 0.016 15.3 0.3 16 5.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Troponin-I_N PF11636.3 KEZ46788.1 - 0.74 9.5 3.3 3.8 7.3 2.3 2.3 1 0 0 1 1 1 0 Troponin I residues 1-32 Pkinase PF00069.20 KEZ46789.1 - 1.9e-58 197.6 0.0 2.6e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46789.1 - 2.4e-32 112.0 0.0 3.1e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46789.1 - 2.1e-05 23.6 0.0 0.00015 20.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KEZ46789.1 - 0.00054 19.0 0.1 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KEZ46789.1 - 0.0013 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family UL11 PF11094.3 KEZ46789.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein Pox_ser-thr_kin PF05445.6 KEZ46789.1 - 0.023 13.4 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 KEZ46789.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 KEZ46790.1 - 3e-53 180.6 0.0 4e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46790.1 - 5.3e-24 84.6 0.0 1.1e-23 83.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46790.1 - 0.00095 18.2 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KEZ46790.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KEZ46790.1 - 0.074 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family TMA7 PF09072.5 KEZ46791.1 - 4.2e-25 87.9 18.6 4.7e-25 87.8 12.9 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF3486 PF11985.3 KEZ46791.1 - 0.068 13.2 0.5 0.066 13.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) LptE PF04390.7 KEZ46791.1 - 0.084 12.6 0.1 0.099 12.3 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Amidase PF01425.16 KEZ46792.1 - 6.2e-91 305.4 0.0 7.1e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.3 KEZ46793.1 - 1.6e-13 50.0 5.1 1.1e-12 47.3 3.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KEZ46793.1 - 5.8e-08 31.8 34.2 1e-05 24.4 6.6 3.6 2 1 2 4 4 4 3 Major Facilitator Superfamily CENP-B_N PF04218.8 KEZ46793.1 - 0.0063 15.9 0.3 0.016 14.5 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HlyIII PF03006.15 KEZ46794.1 - 1.6e-62 210.8 14.2 2.1e-62 210.4 9.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related WD40 PF00400.27 KEZ46795.1 - 0.038 13.8 0.2 6.9 6.7 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat TPR_19 PF14559.1 KEZ46796.1 - 0.00048 20.4 2.4 0.022 15.1 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ46796.1 - 0.019 14.6 1.0 1.7 8.3 0.1 3.1 3 1 1 4 4 4 0 TPR repeat Rep_fac_C PF08542.6 KEZ46796.1 - 0.021 14.8 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain Apc3 PF12895.2 KEZ46796.1 - 0.043 13.9 0.0 0.2 11.8 0.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KEZ46796.1 - 0.046 14.1 0.5 2 9.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat YwpF PF14183.1 KEZ46796.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 YwpF-like protein ArgJ PF01960.13 KEZ46798.1 - 3.1e-11 42.2 0.0 5e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 ArgJ family CtIP_N PF10482.4 KEZ46798.1 - 0.059 13.1 8.9 0.02 14.6 3.8 1.9 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain TnpV PF14198.1 KEZ46798.1 - 0.069 13.0 1.1 0.17 11.7 0.8 1.7 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF2746 PF10874.3 KEZ46798.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2746) IncA PF04156.9 KEZ46798.1 - 0.25 10.9 5.3 0.31 10.6 2.4 2.0 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 KEZ46798.1 - 1.1 8.0 6.0 2.1 7.1 4.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CorA PF01544.13 KEZ46798.1 - 1.2 8.1 3.3 2.9 6.8 2.3 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HSP70 PF00012.15 KEZ46799.1 - 7e-09 34.1 0.0 3.9e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ46799.1 - 0.005 15.4 0.0 0.018 13.6 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Fringe PF02434.11 KEZ46800.1 - 5.3e-07 29.1 0.1 6.2e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 KEZ46800.1 - 0.0014 18.3 0.7 0.0024 17.5 0.5 1.3 1 0 0 1 1 1 1 PAN domain Oxysterol_BP PF01237.13 KEZ46801.1 - 5e-83 278.5 0.0 6.1e-83 278.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein GMC_oxred_N PF00732.14 KEZ46802.1 - 2.8e-45 154.7 0.0 4.9e-45 153.9 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ46802.1 - 5.8e-28 97.9 0.0 1e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KEZ46802.1 - 4.9e-06 25.6 0.0 0.00019 20.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KEZ46802.1 - 6.1e-05 23.1 0.0 0.00088 19.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KEZ46802.1 - 0.00025 20.9 0.0 0.00074 19.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KEZ46802.1 - 0.00027 19.5 0.0 0.0011 17.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KEZ46802.1 - 0.0022 16.9 0.5 0.017 14.0 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KEZ46802.1 - 0.0023 17.0 0.4 0.0045 16.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 KEZ46802.1 - 0.013 15.3 0.2 0.031 14.1 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KEZ46802.1 - 0.032 14.2 0.2 0.067 13.1 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 KEZ46802.1 - 0.039 12.8 0.1 0.056 12.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 KEZ46802.1 - 0.078 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KEZ46802.1 - 0.087 11.8 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Tim44 PF04280.10 KEZ46803.1 - 2.3e-34 118.4 0.3 8.9e-34 116.5 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain Peptidase_C97 PF05903.9 KEZ46804.1 - 3.6e-32 111.2 0.0 4.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KEZ46804.1 - 0.014 15.3 0.1 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.8 KEZ46805.1 - 1.4e-33 114.5 0.3 3.2e-33 113.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KEZ46805.1 - 2.3e-13 50.1 0.0 7.8e-13 48.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KEZ46805.1 - 0.00021 20.5 0.0 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 KEZ46805.1 - 0.00034 20.3 0.1 0.00086 19.0 0.1 1.7 1 0 0 1 1 1 1 TGS domain BetaGal_dom3 PF13363.1 KEZ46805.1 - 0.0077 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 AAA_14 PF13173.1 KEZ46805.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KEZ46805.1 - 0.032 13.9 0.5 3.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KEZ46805.1 - 0.038 13.8 0.1 2.2 8.0 0.0 2.7 2 1 1 3 3 3 0 Dynamin family VPS9 PF02204.13 KEZ46806.1 - 1.5e-17 63.5 0.0 3.5e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 KEZ46806.1 - 5.1e-15 55.1 0.6 7.8e-11 41.8 0.0 4.7 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KEZ46806.1 - 2.1e-14 53.6 0.0 3.6e-06 27.2 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KEZ46806.1 - 2.4e-13 50.1 0.4 3e-05 24.4 0.0 5.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ46806.1 - 2.2e-08 33.5 0.2 0.14 12.4 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 KEZ46806.1 - 7.9e-07 28.5 0.5 0.00085 19.0 0.0 4.8 4 1 0 4 4 4 1 Ankyrin repeat PX PF00787.19 KEZ46806.1 - 0.016 14.9 0.1 0.07 12.9 0.0 2.1 2 0 0 2 2 2 0 PX domain FliD_N PF02465.13 KEZ46806.1 - 0.19 12.1 7.2 0.28 11.5 1.0 3.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SET PF00856.23 KEZ46807.1 - 3e-10 40.6 0.0 5.5e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 SET domain DUF770 PF05591.7 KEZ46807.1 - 0.074 12.6 0.5 3 7.3 0.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF770) Ldh_1_N PF00056.18 KEZ46808.1 - 8.3e-46 155.3 0.2 1.2e-45 154.7 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KEZ46808.1 - 7.2e-31 107.2 0.0 1.3e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 KEZ46808.1 - 0.00041 19.7 0.3 0.00088 18.6 0.2 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 KEZ46808.1 - 0.0009 19.6 0.2 0.0027 18.1 0.1 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.19 KEZ46808.1 - 0.0011 17.8 1.7 0.002 17.1 0.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KEZ46808.1 - 0.0019 17.9 0.1 0.0034 17.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 KEZ46808.1 - 0.0091 15.9 0.2 0.028 14.3 0.1 1.9 1 1 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KEZ46808.1 - 0.011 15.2 0.8 0.033 13.7 0.5 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 KEZ46808.1 - 0.012 15.3 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 KEZ46808.1 - 0.013 15.6 1.1 0.049 13.7 0.3 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KEZ46808.1 - 0.027 14.7 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_4 PF02056.11 KEZ46808.1 - 0.048 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase GFO_IDH_MocA PF01408.17 KEZ46808.1 - 0.075 13.5 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox PF00070.22 KEZ46808.1 - 0.093 13.1 0.4 0.21 11.9 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KEZ46808.1 - 0.1 12.6 0.6 0.29 11.1 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_3 PF13302.1 KEZ46809.1 - 1.5e-15 57.5 0.0 2.2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KEZ46809.1 - 2.7e-07 30.5 0.0 4.4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KEZ46809.1 - 6.5e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KEZ46809.1 - 7.3e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KEZ46809.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KEZ46809.1 - 0.073 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sulfotransfer_3 PF13469.1 KEZ46810.1 - 2.4e-07 31.7 1.6 4.2e-07 31.0 0.9 1.4 1 1 0 1 1 1 1 Sulfotransferase family CFEM PF05730.6 KEZ46811.1 - 2.2e-07 30.5 9.2 3.1e-07 30.0 6.4 1.2 1 0 0 1 1 1 1 CFEM domain FAD_binding_4 PF01565.18 KEZ46813.1 - 2.8e-25 88.4 3.3 4.9e-25 87.6 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KEZ46813.1 - 4.2e-12 45.7 0.0 7.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cyt-b5 PF00173.23 KEZ46814.1 - 6.5e-11 41.8 0.0 9.2e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M43 PF05572.8 KEZ46815.1 - 4.4e-18 65.3 0.1 7.7e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KEZ46815.1 - 5.1e-07 29.8 0.0 1.3e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KEZ46815.1 - 3.8e-05 24.2 0.0 0.00012 22.5 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KEZ46815.1 - 0.00011 22.2 1.4 0.00017 21.7 0.8 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 KEZ46815.1 - 0.0082 15.8 0.1 0.017 14.8 0.1 1.6 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.19 KEZ46815.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 KEZ46815.1 - 0.047 13.2 3.7 0.24 10.8 2.6 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TPP_enzyme_N PF02776.13 KEZ46816.1 - 1e-56 191.1 0.1 3.3e-56 189.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KEZ46816.1 - 3.4e-50 169.5 0.1 1e-48 164.8 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KEZ46816.1 - 7.9e-38 129.3 1.6 1.6e-37 128.3 0.3 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain zf-C2H2_4 PF13894.1 KEZ46817.1 - 0.7 10.3 9.6 4 7.9 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KEZ46817.1 - 7.7 7.0 11.0 2.4 8.6 0.3 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type GalKase_gal_bdg PF10509.4 KEZ46818.1 - 9e-21 72.8 0.0 1.7e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KEZ46818.1 - 1.3e-13 50.9 0.0 3.9e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KEZ46818.1 - 4.4e-13 49.0 1.8 4.4e-13 49.0 1.2 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1998 PF09369.5 KEZ46818.1 - 0.039 14.5 0.5 0.12 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1998) Sigma70_r4_2 PF08281.7 KEZ46818.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 RINGv PF12906.2 KEZ46819.1 - 4e-05 23.5 9.5 6.8e-05 22.8 6.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KEZ46819.1 - 0.00014 21.5 9.9 0.00022 20.9 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain DUF2890 PF11081.3 KEZ46819.1 - 0.0095 16.0 13.2 0.0095 16.0 9.1 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF2890) Rad50_zn_hook PF04423.9 KEZ46819.1 - 0.011 15.1 0.1 0.03 13.7 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif FANCL_C PF11793.3 KEZ46819.1 - 0.011 15.6 4.1 0.011 15.6 2.8 1.6 2 0 0 2 2 1 0 FANCL C-terminal domain Pex14_N PF04695.8 KEZ46819.1 - 0.05 13.6 1.1 0.086 12.8 0.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 KEZ46819.1 - 0.067 11.2 8.6 0.088 10.8 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein zf-rbx1 PF12678.2 KEZ46819.1 - 0.93 9.6 5.7 1.8 8.7 4.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Lin-8 PF03353.10 KEZ46819.1 - 1.1 8.5 12.0 1.7 7.8 8.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-C3HC4_3 PF13920.1 KEZ46819.1 - 1.4 8.6 6.6 2.4 7.8 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF605 PF04652.11 KEZ46819.1 - 2.6 7.3 12.1 3.7 6.8 8.4 1.1 1 0 0 1 1 1 0 Vta1 like zf-C3HC4 PF00097.20 KEZ46819.1 - 3 7.5 8.2 5 6.8 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Suf PF05843.9 KEZ46819.1 - 3.1 7.4 5.1 4.4 6.9 3.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.7 KEZ46819.1 - 3.5 5.4 15.0 4.6 5.0 10.4 1.1 1 0 0 1 1 1 0 Nop14-like family zf-RING_4 PF14570.1 KEZ46819.1 - 4.3 6.9 8.3 8.1 6.1 5.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SDA1 PF05285.7 KEZ46819.1 - 7.4 5.7 14.8 9.8 5.3 10.3 1.1 1 0 0 1 1 1 0 SDA1 Trypan_PARP PF05887.6 KEZ46819.1 - 7.5 6.3 27.7 13 5.5 19.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TPR_11 PF13414.1 KEZ46820.1 - 5.5e-21 73.9 5.0 7.3e-17 60.7 2.5 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KEZ46820.1 - 2.3e-18 64.9 2.1 4.8e-07 29.1 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KEZ46820.1 - 1.2e-16 59.1 5.2 1.3e-06 27.9 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ46820.1 - 1.6e-10 40.2 1.7 4.5e-05 23.3 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46820.1 - 2.4e-10 40.7 15.6 3e-07 30.9 4.9 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KEZ46820.1 - 1e-09 38.1 6.1 0.00047 20.5 0.6 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ46820.1 - 1.2e-07 31.5 6.8 4.9e-05 23.1 2.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46820.1 - 1.1e-06 28.8 2.0 2.4e-05 24.5 1.2 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46820.1 - 1.9e-06 27.2 0.6 0.027 14.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46820.1 - 0.00014 21.4 0.8 0.17 11.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KEZ46820.1 - 0.0003 21.0 3.4 0.86 10.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KEZ46820.1 - 0.00068 19.4 6.3 0.0038 17.0 1.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 KEZ46820.1 - 0.0046 17.2 1.9 1 9.6 0.1 2.2 1 1 1 2 2 2 2 Bacterial transcriptional activator domain XPC-binding PF09280.6 KEZ46820.1 - 0.025 14.0 4.2 0.026 13.9 1.8 1.9 2 0 0 2 2 2 0 XPC-binding domain TPR_10 PF13374.1 KEZ46820.1 - 0.1 12.5 6.0 3.8 7.5 0.3 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat FAT PF02259.18 KEZ46820.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.5 1 1 0 1 1 1 0 FAT domain MIT PF04212.13 KEZ46820.1 - 2 8.3 5.5 0.79 9.6 0.2 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ABC_tran PF00005.22 KEZ46821.1 - 2.3e-34 118.6 0.0 4.7e-34 117.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KEZ46821.1 - 1.3e-13 51.0 2.0 2.8e-13 49.8 1.4 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF258 PF03193.11 KEZ46821.1 - 8.5e-05 21.7 0.1 0.0005 19.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KEZ46821.1 - 0.00016 22.4 0.0 0.0006 20.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.14 KEZ46821.1 - 0.00049 19.3 0.0 0.0055 15.9 0.0 1.8 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KEZ46821.1 - 0.0007 19.6 0.1 0.0037 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KEZ46821.1 - 0.006 16.0 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain PAM2 PF07145.10 KEZ46821.1 - 0.011 15.2 0.2 0.024 14.1 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region AAA_18 PF13238.1 KEZ46821.1 - 0.017 15.4 0.0 0.062 13.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 KEZ46821.1 - 0.018 14.5 0.1 0.045 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KEZ46821.1 - 0.026 14.1 0.1 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KEZ46821.1 - 0.03 13.4 0.0 0.068 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 KEZ46821.1 - 0.037 14.3 0.1 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KEZ46821.1 - 0.046 13.8 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KEZ46821.1 - 0.071 13.0 0.2 0.43 10.5 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KEZ46821.1 - 0.087 12.8 0.7 0.37 10.7 0.5 2.1 1 1 0 1 1 1 0 AAA ATPase domain PBP PF01161.15 KEZ46822.1 - 4.8e-12 45.9 0.1 7.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Whi5 PF08528.6 KEZ46822.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Whi5 like Vps35 PF03635.12 KEZ46823.1 - 0 1014.9 0.0 0 1014.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TFR_dimer PF04253.10 KEZ46824.1 - 9.6e-25 86.5 0.0 1.7e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KEZ46824.1 - 8.6e-13 48.4 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KEZ46824.1 - 3.3e-06 26.7 0.1 6.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 PA domain TPR_10 PF13374.1 KEZ46825.1 - 2.3e-74 243.4 13.2 8e-11 41.4 0.0 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.1 KEZ46825.1 - 1.6e-55 184.9 20.7 4.1e-16 58.6 0.1 5.2 4 1 2 6 6 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 KEZ46825.1 - 9.1e-20 68.8 17.3 0.0014 18.2 0.1 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 KEZ46825.1 - 2.4e-14 52.6 10.0 8.2e-06 25.3 0.3 5.2 2 1 2 5 5 5 4 TPR repeat TPR_2 PF07719.12 KEZ46825.1 - 4.4e-13 48.0 20.4 0.0032 17.2 0.5 8.0 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 KEZ46825.1 - 1e-12 47.1 4.7 0.2 11.9 0.0 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 KEZ46825.1 - 1.7e-12 46.4 11.2 0.099 13.1 0.1 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KEZ46825.1 - 1.8e-12 46.3 11.0 0.022 14.3 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KEZ46825.1 - 8.4e-08 32.4 11.6 0.15 12.4 0.0 6.6 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KEZ46825.1 - 1.2e-07 32.1 16.0 0.0068 17.0 0.7 6.2 4 2 3 7 7 6 4 Tetratricopeptide repeat NB-ARC PF00931.17 KEZ46825.1 - 1.2e-07 30.8 0.0 2.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 KEZ46825.1 - 4.5e-07 29.9 21.3 0.058 14.0 0.0 8.9 8 2 2 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 KEZ46825.1 - 7.4e-07 28.5 11.8 0.21 11.4 0.1 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KEZ46825.1 - 1.6e-06 28.1 5.6 0.043 13.9 0.0 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 KEZ46825.1 - 2.2e-06 27.8 0.0 3.5e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain PGAP1 PF07819.8 KEZ46825.1 - 0.00012 21.7 0.0 0.00052 19.6 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein TPR_6 PF13174.1 KEZ46825.1 - 0.00092 19.5 16.4 0.38 11.3 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat PPR PF01535.15 KEZ46825.1 - 0.0026 17.6 1.7 17 5.6 0.0 5.5 7 0 0 7 7 6 0 PPR repeat DUF676 PF05057.9 KEZ46825.1 - 0.0046 16.2 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) SNAP PF14938.1 KEZ46825.1 - 0.0054 15.9 0.4 1.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP DUF1615 PF07759.7 KEZ46825.1 - 0.0097 14.7 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1615) Cutinase PF01083.17 KEZ46825.1 - 0.027 14.1 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Cutinase TPR_3 PF07720.7 KEZ46825.1 - 0.066 13.0 0.0 2.4 8.0 0.0 3.5 5 0 0 5 5 4 0 Tetratricopeptide repeat AATase PF07247.7 KEZ46826.1 - 9.9e-21 73.8 0.0 2.3e-20 72.6 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.11 KEZ46826.1 - 1.2e-07 31.6 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.15 KEZ46826.1 - 1.4e-07 30.7 0.0 2.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Condensation domain Glyco_transf_54 PF04666.8 KEZ46827.1 - 8.6e-07 27.9 0.0 1.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF4131 PF13567.1 KEZ46827.1 - 0.41 10.0 6.4 3.6 6.9 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF221 PF02714.10 KEZ46828.1 - 1.8e-94 316.2 15.3 3e-94 315.5 10.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KEZ46828.1 - 3e-40 137.3 0.9 7.7e-40 136.0 0.6 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KEZ46828.1 - 1.3e-16 60.8 0.4 2.7e-16 59.8 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Glycos_transf_2 PF00535.21 KEZ46830.1 - 1.1e-33 116.3 0.0 1.3e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KEZ46830.1 - 4.7e-14 52.7 0.0 7.3e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KEZ46830.1 - 1.3e-08 34.3 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KEZ46830.1 - 2e-05 23.9 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 KEZ46830.1 - 0.041 14.2 0.0 0.072 13.4 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 SAC3_GANP PF03399.11 KEZ46831.1 - 0.00013 21.6 0.1 0.0002 21.0 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KEZ46831.1 - 0.0077 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PPR_1 PF12854.2 KEZ46831.1 - 0.11 12.0 0.1 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 PPR repeat DUF1814 PF08843.6 KEZ46832.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) IBR PF01485.16 KEZ46834.1 - 7.4e-07 28.9 37.5 9.2e-07 28.6 9.4 3.8 2 1 1 3 3 3 2 IBR domain Spt20 PF12090.3 KEZ46835.1 - 1.9e-42 144.6 0.0 1.9e-42 144.6 0.0 6.4 3 2 0 3 3 3 1 Spt20 family ATG27 PF09451.5 KEZ46836.1 - 4.3e-71 239.3 0.0 6.7e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Diphthamide_syn PF01866.12 KEZ46837.1 - 6.4e-115 383.6 0.0 7.6e-115 383.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Ribosomal_S6e PF01092.14 KEZ46838.1 - 9e-60 199.9 0.1 1.8e-59 198.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.4 KEZ46838.1 - 3.9 6.3 8.4 4.9 6.0 5.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OHCU_decarbox PF09349.5 KEZ46839.1 - 0.034 14.4 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 OHCU decarboxylase Steroid_dh PF02544.11 KEZ46840.1 - 6e-33 113.7 0.2 9.9e-33 113.0 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KEZ46840.1 - 5.7e-06 25.7 1.9 8.2e-06 25.2 0.4 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KEZ46840.1 - 0.0015 18.6 1.1 0.0019 18.2 0.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase SOG2 PF10428.4 KEZ46841.1 - 6.2e-93 311.8 0.0 6.2e-93 311.8 0.0 3.1 4 0 0 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 KEZ46841.1 - 1.7e-17 62.6 11.3 5.2e-08 32.3 0.3 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KEZ46841.1 - 4.2e-15 55.2 4.0 2.5e-08 33.5 0.2 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KEZ46841.1 - 1.2e-10 39.8 9.7 0.42 10.8 0.0 6.0 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 KEZ46841.1 - 5.4e-08 31.7 5.4 2.9 8.4 0.1 5.5 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KEZ46841.1 - 0.00074 19.3 6.2 1.2 9.4 0.1 5.3 6 0 0 6 6 6 1 Leucine Rich repeat Helicase_C PF00271.26 KEZ46842.1 - 2e-19 69.2 0.0 1.6e-16 59.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 KEZ46842.1 - 5.4e-18 65.0 0.0 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSP70 PF00012.15 KEZ46843.1 - 2.1e-270 897.8 6.2 2.4e-270 897.6 4.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KEZ46843.1 - 4.9e-17 61.5 0.0 7.2e-16 57.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KEZ46843.1 - 0.004 16.8 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KEZ46843.1 - 0.011 14.8 0.0 0.042 12.9 0.0 1.9 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KEZ46843.1 - 0.074 12.9 3.5 6.5 6.6 0.4 3.3 2 2 0 2 2 2 0 Cell division protein FtsA DUF1843 PF08898.5 KEZ46843.1 - 1.6 8.7 4.5 0.97 9.5 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) AAA_23 PF13476.1 KEZ46843.1 - 2.3 8.5 7.9 5.7 7.2 2.5 2.5 2 1 0 2 2 2 0 AAA domain DUF4404 PF14357.1 KEZ46843.1 - 8.2 6.9 7.6 4.9 7.6 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RNA12 PF10443.4 KEZ46844.1 - 3e-130 434.5 0.0 3.9e-130 434.2 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 KEZ46844.1 - 2.1e-06 27.2 0.0 0.00015 21.2 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ46844.1 - 0.004 16.9 0.0 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 KEZ46844.1 - 0.01 15.5 0.2 0.032 13.9 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2487 PF10673.4 KEZ46844.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) COPI_C PF06957.6 KEZ46844.1 - 0.042 12.3 0.0 0.086 11.3 0.0 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CENP-C_C PF11699.3 KEZ46845.1 - 1.5e-34 117.8 0.4 2.3e-34 117.2 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 KEZ46845.1 - 3.9e-30 105.2 1.4 3.9e-30 105.2 1.0 3.7 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 KEZ46845.1 - 2.5e-07 30.1 0.0 5.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Cupin domain RHD3 PF05879.7 KEZ46846.1 - 0 1035.3 0.0 0 1035.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KEZ46846.1 - 2.9e-07 29.8 0.2 4.7e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KEZ46846.1 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KEZ46846.1 - 6.3e-05 22.9 0.1 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KEZ46846.1 - 0.00083 19.3 0.1 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KEZ46846.1 - 0.0012 19.2 0.1 0.0024 18.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 KEZ46846.1 - 0.081 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Septin DLH PF01738.13 KEZ46847.1 - 1.6e-22 79.8 0.0 2.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KEZ46847.1 - 2.1e-06 27.5 0.0 2.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KEZ46847.1 - 6.5e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KEZ46847.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.6 KEZ46847.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase MS_channel PF00924.13 KEZ46848.1 - 1.6e-18 66.7 1.1 3.2e-18 65.8 0.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KEZ46848.1 - 0.0065 15.6 0.1 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 KEZ46848.1 - 0.032 13.5 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 KEZ46848.1 - 0.15 12.2 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Abp2 PF09441.5 KEZ46849.1 - 4.4e-73 244.9 0.0 6.9e-73 244.2 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Spc42p PF11544.3 KEZ46849.1 - 0.045 13.6 0.3 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Spindle pole body component Spc42p ARID PF01388.16 KEZ46849.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain TENA_THI-4 PF03070.11 KEZ46849.1 - 0.22 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Methyltransf_23 PF13489.1 KEZ46850.1 - 9.7e-11 41.6 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46850.1 - 8.4e-09 35.8 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46850.1 - 2.8e-06 27.7 0.0 5.8e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46850.1 - 0.00096 18.7 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ46850.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KEZ46850.1 - 0.033 14.7 0.0 0.099 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Sds3 PF08598.6 KEZ46851.1 - 8.6e-48 162.5 1.3 2e-47 161.4 0.9 1.6 1 1 0 1 1 1 1 Sds3-like DUF743 PF05332.6 KEZ46851.1 - 0.74 9.7 5.7 3.3 7.6 0.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF743) Btz PF09405.5 KEZ46852.1 - 0.0033 17.4 0.7 0.0054 16.7 0.1 1.7 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_5 PF13893.1 KEZ46852.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KEZ46853.1 - 6.6e-53 179.4 0.6 1.1e-52 178.7 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46853.1 - 4.4e-23 81.6 0.0 1.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KEZ46853.1 - 0.0008 19.2 0.1 0.0008 19.2 0.1 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ46853.1 - 0.0098 15.2 0.2 0.0098 15.2 0.2 2.1 2 1 0 2 2 2 1 RIO1 family DUF4430 PF14478.1 KEZ46853.1 - 0.099 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Choline_kinase PF01633.15 KEZ46853.1 - 8.5 5.8 9.5 0.7 9.4 0.1 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.17 KEZ46854.1 - 2.7e-59 196.6 0.0 1.9e-21 75.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KEZ46854.1 - 1.7e-44 149.6 0.0 1.5e-14 53.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KEZ46854.1 - 2.9e-30 103.8 0.0 2.2e-10 40.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KEZ46854.1 - 1e-07 31.6 0.1 0.088 12.5 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 KEZ46854.1 - 7.2e-05 22.6 0.0 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 KEZ46854.1 - 0.013 15.2 0.1 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif ApbA PF02558.11 KEZ46854.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_N PF05222.10 KEZ46855.1 - 1.8e-22 79.7 0.0 2.5e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KEZ46855.1 - 3.4e-05 23.4 0.0 0.0015 18.1 0.0 2.1 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain APH PF01636.18 KEZ46857.1 - 4.5e-05 23.2 0.0 7.8e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KEZ46857.1 - 0.00025 20.2 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KEZ46857.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KEZ46857.1 - 0.03 13.2 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase V_ATPase_I PF01496.14 KEZ46857.1 - 0.047 11.5 0.0 0.074 10.9 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_12 PF13087.1 KEZ46858.1 - 2.9e-27 95.3 0.0 4.6e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KEZ46858.1 - 4.2e-20 72.3 0.0 9.2e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KEZ46858.1 - 1.4e-08 34.3 0.0 1.3e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KEZ46858.1 - 7.1e-06 25.7 0.0 0.003 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KEZ46858.1 - 0.00037 20.3 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 KEZ46858.1 - 0.0011 18.3 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KEZ46858.1 - 0.0014 18.8 0.0 0.0046 17.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KEZ46858.1 - 0.0024 17.3 0.1 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KEZ46858.1 - 0.0082 16.2 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KEZ46858.1 - 0.019 14.5 0.1 1 8.8 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KEZ46858.1 - 0.019 14.9 0.0 0.11 12.5 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KEZ46858.1 - 0.019 14.0 0.0 0.054 12.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 KEZ46858.1 - 0.029 13.3 0.0 0.061 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KEZ46858.1 - 0.034 14.9 0.1 0.55 11.0 0.1 3.2 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KEZ46858.1 - 0.053 12.3 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DnaB_C PF03796.10 KEZ46858.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.17 KEZ46858.1 - 0.1 12.7 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 1 0 RNA helicase NB-ARC PF00931.17 KEZ46858.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain UvrD-helicase PF00580.16 KEZ46858.1 - 0.12 11.6 0.1 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain MIF4G PF02854.14 KEZ46859.1 - 8.3e-52 175.6 0.0 1.3e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KEZ46859.1 - 5.9e-14 51.7 0.1 2.5e-13 49.6 0.1 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Eno-Rase_FAD_bd PF07055.7 KEZ46859.1 - 0.059 13.3 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain efThoc1 PF11957.3 KEZ46860.1 - 8.7e-155 515.9 0.1 1.1e-154 515.5 0.0 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KEZ46860.1 - 9.2e-24 83.8 0.0 1.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KEZ46860.1 - 0.00013 21.8 0.1 0.00056 19.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KEZ46860.1 - 0.0083 16.4 0.0 0.027 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KEZ46860.1 - 0.019 14.9 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 KEZ46860.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KEZ46860.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KEZ46860.1 - 0.14 12.3 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KEZ46860.1 - 0.23 12.2 2.0 0.77 10.5 0.0 2.9 3 1 0 3 3 3 0 AAA domain DNA_pol_B PF00136.16 KEZ46861.1 - 7.5e-111 371.1 0.3 1.2e-110 370.4 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KEZ46861.1 - 3.4e-64 215.6 0.3 9.2e-64 214.2 0.0 1.9 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KEZ46861.1 - 6.6e-38 130.3 0.0 1.3e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KEZ46861.1 - 3.8e-24 84.2 7.7 3.8e-24 84.2 5.3 3.2 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Asp PF00026.18 KEZ46862.1 - 3.9e-13 49.3 0.0 4.1e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KEZ46862.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.6 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal DUF3686 PF12458.3 KEZ46862.1 - 0.028 12.7 0.0 0.033 12.4 0.0 1.0 1 0 0 1 1 1 0 ATPase involved in DNA repair Ank_2 PF12796.2 KEZ46863.1 - 3.8e-55 184.1 1.2 4e-20 71.9 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KEZ46863.1 - 4e-47 155.7 8.3 1.2e-07 31.1 0.0 11.6 12 1 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 KEZ46863.1 - 3.6e-45 151.5 8.9 1.7e-09 37.8 0.1 9.8 5 2 6 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KEZ46863.1 - 1.9e-38 126.6 9.6 4.9e-06 26.2 0.0 11.6 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.1 KEZ46863.1 - 1.1e-29 101.7 12.1 0.0016 18.6 0.0 10.1 5 4 6 11 11 11 8 Ankyrin repeats (many copies) DUF4440 PF14534.1 KEZ46863.1 - 0.015 15.5 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF1843 PF08898.5 KEZ46863.1 - 0.11 12.5 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) RVP PF00077.15 KEZ46863.1 - 0.12 12.3 1.7 24 4.9 0.0 4.5 3 2 0 5 5 5 0 Retroviral aspartyl protease Spore_coat_CotO PF14153.1 KEZ46865.1 - 0.014 14.8 6.6 0.084 12.3 3.3 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Daxx PF03344.10 KEZ46865.1 - 0.46 8.9 15.4 0.89 7.9 10.7 1.4 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 KEZ46865.1 - 5.1 6.4 14.2 11 5.3 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 KEZ46865.1 - 7.3 4.3 14.9 14 3.4 10.4 1.4 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 KEZ46866.1 - 1.6e-38 132.3 0.0 2.4e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46866.1 - 3.6e-28 98.3 0.0 5.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46866.1 - 0.00066 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ46866.1 - 0.0026 17.5 0.0 3.3 7.3 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KEZ46866.1 - 0.0057 15.7 0.0 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KEZ46867.1 - 1.5e-60 204.5 0.0 2.1e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46867.1 - 5.9e-20 71.4 0.0 9.1e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KEZ46867.1 - 2.2e-09 36.6 0.0 3.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KEZ46867.1 - 0.00052 19.8 0.3 0.0022 17.7 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KEZ46867.1 - 0.00083 18.7 0.1 0.0015 17.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 KEZ46867.1 - 0.11 12.9 0.0 3.5 8.0 0.0 2.8 2 0 0 2 2 2 0 PAS domain Seadorna_VP7 PF07387.6 KEZ46867.1 - 0.23 10.2 0.1 0.36 9.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2387 PF09526.5 KEZ46868.1 - 4.2 7.3 5.7 18 5.3 0.4 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF2361 PF10153.4 KEZ46869.1 - 2.5e-34 117.8 12.6 2.5e-34 117.8 8.7 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) dsrm PF00035.20 KEZ46870.1 - 0.039 14.5 0.0 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KEZ46870.1 - 0.11 12.7 0.2 28 5.0 0.0 3.1 2 2 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 PTS_2-RNA PF01885.11 KEZ46871.1 - 1.1e-68 230.2 0.0 1.3e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family UAA PF08449.6 KEZ46873.1 - 2.5e-71 240.0 2.9 5.6e-71 238.9 2.0 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KEZ46873.1 - 2.2e-08 34.1 23.5 2.4e-07 30.8 3.1 3.4 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KEZ46873.1 - 1e-06 28.0 1.7 0.003 16.6 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 KEZ46873.1 - 0.0037 17.4 7.3 0.0037 17.4 5.1 3.1 3 1 0 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 KEZ46873.1 - 0.0059 16.2 7.9 0.0059 16.2 5.5 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family DUF2892 PF11127.3 KEZ46873.1 - 0.63 9.9 0.1 0.63 9.9 0.0 3.8 5 1 0 5 5 5 0 Protein of unknown function (DUF2892) KH_1 PF00013.24 KEZ46874.1 - 5.7e-38 128.3 12.2 2.5e-14 52.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KEZ46874.1 - 9.1e-30 101.7 13.1 5.7e-11 41.8 0.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KEZ46874.1 - 9.3e-10 37.9 9.4 0.0098 15.4 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KEZ46874.1 - 1.9e-08 33.8 4.3 0.031 13.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KEZ46874.1 - 0.00027 20.6 5.0 0.55 10.0 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KEZ46874.1 - 0.0042 16.5 0.3 0.5 9.8 0.0 3.1 3 0 0 3 3 3 1 dUTPase RabGAP-TBC PF00566.13 KEZ46875.1 - 2.7e-16 59.6 0.0 4.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.11 KEZ46876.1 - 5.2e-46 156.9 39.8 5.2e-46 156.9 27.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KEZ46876.1 - 1.6e-12 46.7 7.4 1.6e-12 46.7 5.1 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter D-ser_dehydrat PF14031.1 KEZ46877.1 - 3e-26 91.4 0.0 5.5e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KEZ46877.1 - 9.1e-12 44.9 0.0 5.2e-11 42.5 0.0 1.9 1 1 1 2 2 2 1 Alanine racemase, N-terminal domain Tubulin PF00091.20 KEZ46877.1 - 0.13 12.0 0.0 6.3 6.5 0.0 2.3 2 1 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain NPCBM_assoc PF10633.4 KEZ46878.1 - 0.064 13.3 0.1 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase A2M_N PF01835.14 KEZ46878.1 - 0.14 12.4 0.0 12 6.2 0.0 2.5 2 0 0 2 2 2 0 MG2 domain zf-C2H2 PF00096.21 KEZ46879.1 - 3.6e-06 26.9 18.2 9.6e-06 25.6 2.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KEZ46879.1 - 7.5e-05 22.8 4.4 7.5e-05 22.8 3.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KEZ46879.1 - 0.00043 20.4 1.1 0.00043 20.4 0.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ46879.1 - 0.00098 19.1 1.0 0.00098 19.1 0.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KEZ46879.1 - 0.25 11.5 6.0 0.14 12.4 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 KEZ46879.1 - 0.65 10.4 8.2 0.13 12.6 2.5 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_6 PF13912.1 KEZ46879.1 - 0.7 9.8 4.4 3.1 7.8 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KEZ46879.1 - 1.5 8.9 9.2 1.1 9.4 4.2 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF1295 PF06966.7 KEZ46880.1 - 8.7e-36 123.3 7.4 1.1e-35 123.1 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Hydrolase_6 PF13344.1 KEZ46881.1 - 2.2e-26 91.6 0.0 3.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KEZ46881.1 - 5.5e-11 42.0 0.0 9.6e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KEZ46881.1 - 1.1e-10 42.2 0.0 1.9e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KEZ46881.1 - 0.0019 18.4 0.1 5.7 7.1 0.0 3.3 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF4149 PF13664.1 KEZ46882.1 - 1.1e-25 89.6 3.5 1.1e-25 89.6 2.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ni_hydr_CYTB PF01292.15 KEZ46882.1 - 0.018 14.4 1.2 0.05 12.9 0.8 1.7 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 KEZ46882.1 - 0.038 13.3 2.0 0.063 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DnaJ PF00226.26 KEZ46883.1 - 1.6e-07 30.9 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KEZ46883.1 - 0.0001 22.1 0.0 0.00012 21.8 0.0 1.3 1 1 0 1 1 1 1 Pam16 Ku PF02735.11 KEZ46885.1 - 5.4e-23 81.4 0.0 9.5e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KEZ46885.1 - 1.3e-19 70.4 0.0 2.2e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KEZ46885.1 - 7e-13 48.5 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 KEZ46885.1 - 0.00091 19.3 0.3 0.0055 16.8 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain Ribosomal_L24e PF01246.15 KEZ46886.1 - 3.9e-29 100.3 2.6 3.9e-29 100.3 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF3602 PF12223.3 KEZ46887.1 - 4.3e-15 55.8 10.1 2.3e-06 27.9 1.3 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Statherin PF03875.8 KEZ46887.1 - 0.69 9.8 2.7 6.6 6.6 0.3 2.6 2 0 0 2 2 2 0 Statherin zf-C2H2 PF00096.21 KEZ46888.1 - 0.013 15.8 3.4 0.037 14.3 2.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ46888.1 - 0.027 14.8 2.8 0.076 13.3 1.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KEZ46888.1 - 0.17 12.2 1.2 23 5.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 KEZ46888.1 - 0.3 10.8 6.4 0.065 12.9 1.6 2.0 2 0 0 2 2 2 0 BED zinc finger DUF342 PF03961.8 KEZ46890.1 - 5.5e-09 34.9 0.7 2.1e-05 23.1 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF342) Bactofilin PF04519.8 KEZ46890.1 - 1e-06 28.6 0.4 7e-05 22.7 0.1 2.2 1 1 1 2 2 2 2 Polymer-forming cytoskeletal MinC_C PF03775.11 KEZ46890.1 - 2e-05 24.1 3.1 0.0013 18.3 0.7 2.4 1 1 1 2 2 2 2 Septum formation inhibitor MinC, C-terminal domain DUF748 PF05359.6 KEZ46890.1 - 0.00059 19.8 0.0 0.26 11.2 0.0 2.5 1 1 0 2 2 2 2 Domain of Unknown Function (DUF748) PHD PF00628.24 KEZ46891.1 - 7.3e-09 35.1 6.8 1.2e-08 34.4 4.7 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KEZ46891.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.7 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-MIZ PF02891.15 KEZ46891.1 - 0.24 10.9 1.8 0.49 9.9 1.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DPM2 PF07297.7 KEZ46893.1 - 2.7e-36 123.6 3.4 3.2e-36 123.4 2.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KEZ46893.1 - 2.7e-06 27.0 1.1 3e-06 26.8 0.8 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KEZ46893.1 - 0.00037 20.3 0.4 0.00037 20.3 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 KEZ46893.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) DUF1469 PF07332.6 KEZ46893.1 - 0.0027 17.4 2.6 0.0035 17.0 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) LMF1 PF06762.9 KEZ46893.1 - 0.13 11.0 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Lipase maturation factor DUF3169 PF11368.3 KEZ46893.1 - 0.72 9.0 4.3 0.93 8.6 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) PspC PF04024.7 KEZ46893.1 - 0.95 8.9 6.6 4.6 6.7 1.0 2.1 2 0 0 2 2 2 0 PspC domain DUF1049 PF06305.6 KEZ46893.1 - 4.2 6.9 8.2 0.12 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TPPK_C PF12555.3 KEZ46893.1 - 6.2 6.6 9.5 2.6 7.8 0.5 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Dus PF01207.12 KEZ46894.1 - 1.1e-59 201.8 0.0 1.8e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF849 PF05853.7 KEZ46894.1 - 0.084 11.7 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) DUF2188 PF09954.4 KEZ46894.1 - 0.16 11.9 1.9 14 5.7 0.1 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF4231 PF14015.1 KEZ46896.1 - 0.18 11.8 1.1 10 6.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2077 PF09850.4 KEZ46896.1 - 0.2 11.0 1.2 0.67 9.3 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) Carb_anhydrase PF00194.16 KEZ46898.1 - 5.1e-23 81.3 0.0 1.7e-22 79.6 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AAA PF00004.24 KEZ46899.1 - 1.4e-47 161.2 0.0 5.5e-42 143.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KEZ46899.1 - 9.1e-09 35.5 0.6 1.8e-05 24.8 0.0 4.1 3 1 0 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 KEZ46899.1 - 1.1e-06 28.1 0.0 7.9e-06 25.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 KEZ46899.1 - 3.4e-06 27.0 0.0 9.7e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KEZ46899.1 - 2.1e-05 24.6 0.0 0.00071 19.7 0.0 3.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KEZ46899.1 - 0.00035 20.4 0.5 0.017 15.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KEZ46899.1 - 0.00058 19.6 0.0 0.003 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KEZ46899.1 - 0.00074 19.6 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 KEZ46899.1 - 0.0018 19.1 0.1 0.024 15.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KEZ46899.1 - 0.0022 17.8 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 KEZ46899.1 - 0.0044 17.0 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 KEZ46899.1 - 0.0053 16.4 0.0 0.023 14.4 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KEZ46899.1 - 0.0061 16.8 0.1 0.04 14.2 0.0 2.6 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 KEZ46899.1 - 0.0071 16.6 0.8 0.049 13.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter TIP49 PF06068.8 KEZ46899.1 - 0.0099 14.6 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 KEZ46899.1 - 0.012 15.0 0.0 0.037 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KEZ46899.1 - 0.016 14.2 0.0 0.039 12.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KEZ46899.1 - 0.026 14.1 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 KEZ46899.1 - 0.033 14.0 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.16 KEZ46899.1 - 0.035 13.2 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KEZ46899.1 - 0.037 13.4 0.0 0.93 8.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.7 KEZ46899.1 - 0.062 12.9 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.11 KEZ46899.1 - 0.089 12.0 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Cellulase PF00150.13 KEZ46900.1 - 0.077 12.1 0.0 0.089 11.9 0.0 1.0 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 KEZ46901.1 - 9.1e-29 100.3 0.0 1.2e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46901.1 - 1.1e-08 34.4 0.0 9.1e-08 31.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DSBA PF01323.15 KEZ46902.1 - 6.1e-21 74.8 0.0 4.1e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain BCNT PF07572.7 KEZ46903.1 - 8e-27 93.0 0.8 1.8e-26 91.8 0.6 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development SNF2_N PF00176.18 KEZ46904.1 - 5.2e-84 281.5 0.6 5.2e-84 281.5 0.4 2.6 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KEZ46904.1 - 4.6e-20 71.3 0.0 1.6e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KEZ46904.1 - 4.6e-18 64.8 2.3 4.1e-16 58.6 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 KEZ46904.1 - 8.8e-18 64.2 0.8 8.8e-18 64.2 0.6 4.2 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 KEZ46904.1 - 1.9e-13 50.0 11.6 1.9e-13 50.0 8.0 4.3 4 0 0 4 4 4 1 HSA QLQ PF08880.6 KEZ46904.1 - 5.9e-09 35.1 2.9 5.9e-09 35.1 2.0 2.1 2 0 0 2 2 2 1 QLQ DUF4602 PF15375.1 KEZ46905.1 - 3.9 7.5 8.7 0.93 9.5 1.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4602) STE PF02200.11 KEZ46906.1 - 1.2e-61 205.6 0.2 2.4e-61 204.6 0.1 1.5 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 KEZ46906.1 - 0.0003 20.9 3.8 0.00074 19.7 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ46906.1 - 0.00086 19.4 2.3 0.0021 18.2 1.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger Perilipin PF03036.11 KEZ46907.1 - 0.00063 18.6 0.0 0.00074 18.4 0.0 1.1 1 0 0 1 1 1 1 Perilipin family Pirin PF02678.11 KEZ46908.1 - 1.4e-31 108.5 0.0 2.6e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KEZ46908.1 - 1.1e-26 92.9 0.0 1.9e-25 88.9 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KEZ46908.1 - 2.8e-07 29.9 2.9 5e-05 22.7 0.3 2.5 2 0 0 2 2 2 2 Cupin domain CFEM PF05730.6 KEZ46909.1 - 1e-13 50.8 4.3 2e-13 49.9 3.0 1.4 1 0 0 1 1 1 1 CFEM domain Ribonuc_red_lgC PF02867.10 KEZ46910.1 - 2.8e-224 745.6 0.0 3.6e-224 745.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KEZ46910.1 - 4.3e-24 84.1 0.0 1e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KEZ46910.1 - 2.9e-17 62.8 0.0 2.5e-16 59.8 0.0 2.5 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 KEZ46910.1 - 0.0088 14.1 0.0 0.016 13.3 0.0 1.3 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase MMR_HSR1_C PF08438.5 KEZ46910.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 GTPase of unknown function C-terminal TatD_DNase PF01026.16 KEZ46911.1 - 6.3e-46 156.6 0.0 9.2e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 KEZ46911.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase bZIP_2 PF07716.10 KEZ46912.1 - 1.1e-12 47.5 11.4 2.4e-12 46.4 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KEZ46912.1 - 0.00015 21.6 13.0 0.00057 19.7 9.0 1.9 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 KEZ46912.1 - 0.027 14.3 3.5 0.057 13.3 2.4 1.6 1 0 0 1 1 1 0 Haemolysin XhlA IncA PF04156.9 KEZ46912.1 - 0.038 13.5 12.5 0.051 13.1 8.7 1.1 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 KEZ46912.1 - 1.3 7.1 12.5 1.7 6.8 8.6 1.0 1 0 0 1 1 1 0 Transmembrane protein MCC-bdg_PDZ PF10506.4 KEZ46912.1 - 3.6 7.4 7.3 12 5.8 0.1 2.3 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Pkinase PF00069.20 KEZ46913.1 - 7.7e-66 221.8 0.0 1.2e-65 221.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KEZ46913.1 - 6.6e-30 104.0 0.0 1.8e-29 102.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase SWIB PF02201.13 KEZ46913.1 - 2.7e-11 42.9 0.0 6.3e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Kdo PF06293.9 KEZ46913.1 - 0.0015 17.6 0.0 0.0035 16.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KEZ46913.1 - 0.0029 16.6 0.3 0.24 10.3 0.0 2.9 2 1 0 2 2 2 1 Kinase-like Mo25 PF08569.6 KEZ46914.1 - 9.9e-121 402.8 0.0 1.1e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 KEZ46914.1 - 0.065 13.0 0.2 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus DUF544 PF04424.8 KEZ46914.1 - 0.088 12.6 0.1 0.33 10.7 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF544) Sfi1 PF08457.5 KEZ46915.1 - 2.5e-31 108.7 56.2 6.2e-20 71.1 20.9 2.9 1 1 2 3 3 3 2 Sfi1 spindle body protein DUF1765 PF08578.5 KEZ46915.1 - 0.71 9.9 4.4 5.3 7.1 0.0 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1765) Rav1p_C PF12234.3 KEZ46916.1 - 1.6e-246 819.4 0.0 2e-246 819.1 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 KEZ46916.1 - 0.011 15.6 5.3 5 7.1 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat OPT PF03169.10 KEZ46917.1 - 4.1e-128 428.5 21.5 5.4e-128 428.1 14.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Transgly_assoc PF04226.8 KEZ46917.1 - 0.029 14.4 1.4 0.029 14.4 0.9 4.4 5 0 0 5 5 5 0 Transglycosylase associated protein Uso1_p115_head PF04869.9 KEZ46918.1 - 8.1e-102 340.1 0.0 1.5e-101 339.2 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KEZ46918.1 - 2.5e-09 37.1 20.9 2.5e-09 37.1 14.5 4.1 2 1 2 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_11 PF08241.7 KEZ46918.1 - 4.7e-05 23.7 0.0 0.00016 22.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KEZ46918.1 - 0.002 17.1 0.0 0.0044 15.9 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 KEZ46918.1 - 0.002 17.2 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 KEZ46918.1 - 0.054 13.0 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Filament PF00038.16 KEZ46918.1 - 1.1 8.6 43.1 0.11 11.9 13.5 3.1 2 1 1 3 3 3 0 Intermediate filament protein LCD1 PF09798.4 KEZ46918.1 - 4.4 5.1 12.1 8 4.3 8.4 1.4 1 0 0 1 1 1 0 DNA damage checkpoint protein XRN_N PF03159.13 KEZ46919.1 - 8.6e-108 359.1 0.2 4.9e-107 356.7 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_3 PF13917.1 KEZ46919.1 - 0.022 14.5 4.4 0.047 13.4 3.1 1.5 1 0 0 1 1 1 0 Zinc knuckle RasGAP PF00616.14 KEZ46920.1 - 3.4e-29 101.9 0.0 8.4e-29 100.6 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Aldedh PF00171.17 KEZ46921.1 - 2.7e-130 434.7 0.2 3.2e-114 381.8 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 KEZ46921.1 - 2.3e-06 26.5 0.0 3.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Fungal_trans PF04082.13 KEZ46922.1 - 5e-06 25.5 0.1 9.8e-06 24.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.7 KEZ46923.1 - 7.1e-23 80.4 2.1 1.2e-22 79.6 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KEZ46923.1 - 6.9e-22 77.3 0.3 1.1e-21 76.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD-oxidase_C PF02913.14 KEZ46924.1 - 3.4e-34 118.2 0.0 4.5e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KEZ46924.1 - 1.3e-28 99.2 0.0 2.3e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Tannase PF07519.6 KEZ46925.1 - 4.3e-96 322.4 1.0 5e-96 322.2 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KEZ46925.1 - 4e-07 30.1 2.8 2.2e-06 27.6 2.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KEZ46925.1 - 1.5e-05 24.7 1.2 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KEZ46925.1 - 4.9e-05 22.6 0.2 0.0095 15.1 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KEZ46925.1 - 0.0088 15.6 0.7 0.024 14.2 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 KEZ46926.1 - 2.1e-17 63.4 0.3 1.1e-16 61.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46926.1 - 3.2e-16 59.2 0.0 9.5e-16 57.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ46926.1 - 3e-12 46.5 0.0 6.2e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46926.1 - 8.8e-12 45.6 0.0 2.5e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46926.1 - 1.4e-10 41.4 0.0 4.1e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ46926.1 - 1.1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ46926.1 - 7.6e-05 21.9 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KEZ46926.1 - 0.003 16.9 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_N PF08240.7 KEZ46926.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain RrnaAD PF00398.15 KEZ46926.1 - 0.031 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 KEZ46926.1 - 0.061 12.7 0.1 0.4 10.1 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase DREV PF05219.7 KEZ46926.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.6 KEZ46926.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 KEZ46926.1 - 0.081 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 KEZ46926.1 - 0.12 13.2 0.1 0.47 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Hydantoinase_B PF02538.9 KEZ46927.1 - 5.6e-177 589.1 0.0 7.8e-177 588.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KEZ46927.1 - 1.2e-94 316.6 0.2 5.8e-94 314.4 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KEZ46927.1 - 5.6e-45 152.9 0.0 2.1e-42 144.6 0.0 3.6 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 KEZ46928.1 - 4.3e-33 114.5 21.8 6.3e-33 113.9 15.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 KEZ46928.1 - 3.3e-06 26.9 6.8 5.4e-06 26.2 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 KEZ46928.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper PepSY_TM PF03929.11 KEZ46928.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.6 2 0 0 2 2 2 0 PepSY-associated TM helix Methyltransf_18 PF12847.2 KEZ46929.1 - 3.8e-09 37.1 0.0 2.1e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KEZ46929.1 - 1.4e-08 34.6 0.0 4.1e-08 33.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46929.1 - 8.7e-07 28.6 0.0 2.2e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KEZ46929.1 - 2.5e-06 27.5 0.0 4.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KEZ46929.1 - 3.7e-05 22.8 0.0 5.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KEZ46929.1 - 4.2e-05 23.8 0.0 7.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46929.1 - 9.9e-05 22.7 0.0 0.0002 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46929.1 - 0.00032 21.1 0.0 0.00063 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ46929.1 - 0.00039 19.8 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KEZ46929.1 - 0.00076 19.5 0.0 0.00098 19.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KEZ46929.1 - 0.0032 16.6 0.0 0.0044 16.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 KEZ46929.1 - 0.0041 16.2 0.0 0.19 10.7 0.0 2.1 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KEZ46929.1 - 0.0058 15.7 0.0 0.027 13.5 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FmrO PF07091.6 KEZ46929.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_16 PF10294.4 KEZ46929.1 - 0.08 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 KEZ46929.1 - 0.098 12.1 0.0 0.34 10.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF938) Glyoxalase_2 PF12681.2 KEZ46930.1 - 7e-05 23.3 0.0 0.00026 21.5 0.0 2.0 1 0 0 1 1 1 1 Glyoxalase-like domain F-box PF00646.28 KEZ46930.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.4 3 0 0 3 3 3 0 F-box domain Bac_Ubq_Cox PF01654.12 KEZ46931.1 - 0.067 11.5 0.1 0.1 10.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase DUF1449 PF07290.6 KEZ46931.1 - 0.079 12.2 2.2 0.12 11.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Ank_4 PF13637.1 KEZ46932.1 - 0.027 14.9 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Zn_clus PF00172.13 KEZ46933.1 - 1.6e-08 34.2 8.1 3e-08 33.4 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase_2 PF12681.2 KEZ46934.1 - 1e-08 35.7 0.1 1.3e-08 35.4 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KEZ46934.1 - 3e-05 23.9 0.1 0.00043 20.2 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SLAC1 PF03595.12 KEZ46935.1 - 6.7e-37 126.8 22.8 8.4e-37 126.5 15.8 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel TGS PF02824.16 KEZ46935.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 TGS domain CcmH PF03918.9 KEZ46935.1 - 1.4 7.8 3.3 16 4.4 0.2 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Methyltransf_23 PF13489.1 KEZ46936.1 - 5.1e-19 68.5 0.0 9.9e-19 67.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46936.1 - 4.9e-12 46.1 0.0 9.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KEZ46936.1 - 8e-11 41.7 0.0 5.5e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KEZ46936.1 - 1.5e-10 41.6 0.0 2.1e-09 37.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KEZ46936.1 - 1.9e-09 37.8 0.0 6.5e-09 36.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KEZ46936.1 - 3.2e-09 37.1 0.0 1.1e-08 35.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ46936.1 - 1.3e-06 27.7 0.0 3.4e-05 23.0 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 KEZ46936.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KEZ46936.1 - 1.5e-05 24.1 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KEZ46936.1 - 0.00016 21.7 0.0 0.0011 18.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KEZ46936.1 - 0.00079 18.8 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KEZ46936.1 - 0.0085 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KEZ46936.1 - 0.086 11.9 0.0 0.2 10.6 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FmrO PF07091.6 KEZ46936.1 - 0.094 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 KEZ46936.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase TauD PF02668.11 KEZ46937.1 - 3.1e-29 102.4 0.0 3.9e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease_2 PF13520.1 KEZ46938.1 - 1.1e-72 244.9 35.6 1.3e-72 244.6 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KEZ46938.1 - 1.9e-18 66.0 34.2 4.3e-18 64.9 23.7 1.6 1 1 0 1 1 1 1 Amino acid permease DUF605 PF04652.11 KEZ46939.1 - 8.1 5.7 12.8 11 5.3 8.9 1.1 1 0 0 1 1 1 0 Vta1 like Polysacc_deac_1 PF01522.16 KEZ46940.1 - 4.8e-34 116.6 0.0 7.1e-34 116.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KEZ46940.1 - 0.00015 20.8 0.0 0.0002 20.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Chitin_bind_1 PF00187.14 KEZ46940.1 - 0.012 15.5 19.2 0.027 14.4 12.9 1.9 1 1 0 1 1 1 0 Chitin recognition protein FlbD PF06289.6 KEZ46940.1 - 0.16 11.3 0.0 0.45 9.9 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein (FlbD) zf-H2C2_2 PF13465.1 KEZ46942.1 - 2e-16 59.3 19.1 2.1e-09 37.1 0.5 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KEZ46942.1 - 1.7e-15 56.3 15.0 5e-05 23.3 0.1 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KEZ46942.1 - 3.1e-10 39.6 17.4 0.00047 20.2 0.1 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 KEZ46942.1 - 0.073 13.3 0.1 0.073 13.3 0.1 4.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KEZ46942.1 - 0.23 11.4 0.1 0.23 11.4 0.1 4.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KEZ46942.1 - 0.77 9.9 4.7 3.8 7.7 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 KEZ46942.1 - 1.2 9.1 5.2 12 5.9 0.1 3.5 4 0 0 4 4 4 0 Zinc ribbon domain CHORD PF04968.7 KEZ46942.1 - 7.8 6.8 13.9 13 6.1 0.8 4.3 3 1 2 5 5 5 0 CHORD GFO_IDH_MocA PF01408.17 KEZ46943.1 - 2.1e-23 83.0 0.3 3.5e-23 82.3 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KEZ46943.1 - 0.0058 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 KEZ46944.1 - 2.5e-55 187.7 0.1 3.1e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KEZ46944.1 - 7.3e-38 130.0 0.1 1.3e-37 129.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KEZ46944.1 - 2.2e-07 30.1 0.2 0.0035 16.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KEZ46944.1 - 1e-06 28.8 0.2 0.024 14.5 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KEZ46944.1 - 0.00029 19.8 0.5 0.0013 17.6 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KEZ46944.1 - 0.0026 17.7 0.1 0.0067 16.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KEZ46944.1 - 0.01 15.8 0.6 4.4 7.2 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KEZ46944.1 - 0.11 10.9 0.5 0.2 10.0 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_3 PF07859.8 KEZ46945.1 - 1.7e-48 165.0 0.7 2.1e-48 164.6 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 KEZ46945.1 - 1.3e-08 34.0 0.0 1.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KEZ46945.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KEZ46945.1 - 6.3e-05 22.9 0.1 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 KEZ46946.1 - 4.3e-14 52.0 1.3 4.3e-14 52.0 0.9 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KEZ46946.1 - 1.8e-05 24.5 11.0 3.8e-05 23.5 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 KEZ46947.1 - 1.9e-21 77.0 0.0 3.2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KEZ46947.1 - 9.3e-21 73.6 0.5 1.2e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KEZ46947.1 - 1.6e-11 44.0 0.0 4.1e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KEZ46947.1 - 2.2e-07 30.1 0.0 3.7e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KEZ46947.1 - 0.0008 19.2 0.0 0.0024 17.6 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KEZ46947.1 - 0.15 12.4 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Defensin_2 PF01097.13 KEZ46948.1 - 3e-05 23.6 8.9 4.2e-05 23.1 6.2 1.3 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.15 KEZ46948.1 - 0.73 9.8 5.9 1 9.4 4.1 1.2 1 0 0 1 1 1 0 Gamma-thionin family Toxin_3 PF00537.13 KEZ46948.1 - 2 8.3 7.8 2.7 7.9 5.4 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain PIG-L PF02585.12 KEZ46950.1 - 3.4e-24 85.7 0.0 4.9e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HNH_2 PF13391.1 KEZ46951.1 - 0.00033 20.3 0.2 0.00095 18.8 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease LysM PF01476.15 KEZ46952.1 - 3.8e-10 39.4 0.0 9.8e-10 38.1 0.0 1.7 2 0 0 2 2 2 1 LysM domain Methyltransf_23 PF13489.1 KEZ46953.1 - 0.0027 17.4 0.0 0.0046 16.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KEZ46953.1 - 0.018 15.5 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KEZ46953.1 - 0.024 13.7 0.0 0.57 9.2 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family